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Sample records for igpro20 csl bern

  1. Peripatetic Highlights in Bern

    Science.gov (United States)

    Hentschel, Ann M.

    The capital city of the Swiss Canton of Bern and of the Swiss Confederation is nestled in a narrow loop of the Aare river, at the foot of the Alps. The old town, founded around 1191, is well preserved despite a devastating fire in 1405.** Major industries of the region developed under the constraints of modest domestic markets, high transportation costs, and protectionist legislation across national borders. Switzerland thus found its niche in higher-end markets, such as chocolate making, engine building, instruments, fine textiles, and chemicals or pharmaceuticals. My tour past historically significant scientific sites in Bern will use the local legacy of its most illustrious residents, Albert Einstein (1879-1955), who lived there from 1902-1909, and Fritz Houtermans (1903-1966), who lived there from 1952-1966, as its guiding thread through the old town and the university district. Place names in italics mark stops along the tour.

  2. Dissipative Continuous Spontaneous Localization (CSL) model.

    Science.gov (United States)

    Smirne, Andrea; Bassi, Angelo

    2015-08-05

    Collapse models explain the absence of quantum superpositions at the macroscopic scale, while giving practically the same predictions as quantum mechanics for microscopic systems. The Continuous Spontaneous Localization (CSL) model is the most refined and studied among collapse models. A well-known problem of this model, and of similar ones, is the steady and unlimited increase of the energy induced by the collapse noise. Here we present the dissipative version of the CSL model, which guarantees a finite energy during the entire system's evolution, thus making a crucial step toward a realistic energy-conserving collapse model. This is achieved by introducing a non-linear stochastic modification of the Schrödinger equation, which represents the action of a dissipative finite-temperature collapse noise. The possibility to introduce dissipation within collapse models in a consistent way will have relevant impact on the experimental investigations of the CSL model, and therefore also on the testability of the quantum superposition principle.

  3. Automata-Based CSL Model Checking

    DEFF Research Database (Denmark)

    Zhang, Lijun; Jansen, David N.; Nielson, Flemming

    2011-01-01

    For continuous-time Markov chains, the model-checking problem with respect to continuous-time stochastic logic (CSL) has been introduced and shown to be decidable by Aziz, Sanwal, Singhal and Brayton in 1996. The presented decision procedure, however, has exponential complexity. In this paper, we...

  4. Furniture firms shuns CSL for EMS program expansion

    Energy Technology Data Exchange (ETDEWEB)

    Deans, B

    1982-05-31

    The R.B. Furniture Company's disappointment in its 10 CSL Industries Inc. energy-management systems is responsible for a decision to install Trimax Controls in the remaining 67 stores. At issue are CSL's service policy of using independent installers and service contractors as well as technical problems with the equipment, although R.B. Furniture concedes it had a 2.5-year payback, a 20% drop in electricity consumption, and generally reliable performance of the CSL system. A CSL official claims its higher equipment costs are the real reason. Interviews with CSL and R.B. Furniture Co. representatives explore the attitudes and problems of both firms. The Trimex system includes a three-year warranty. (DCK)

  5. Emergence of inflationary perturbations in the CSL model

    International Nuclear Information System (INIS)

    Leon, Gabriel; Bengochea, Gabriel R.

    2016-01-01

    The inflationary paradigm is the most successful model that explains the observed spectrum of primordial perturbations. However, the precise emergence of such inhomogeneities and the quantum-to-classical transition of the perturbations has not yet reached a consensus among the community. The continuous spontaneous localization model (CSL), in the cosmological context, might be used to provide a solution to the mentioned issues by considering a dynamical reduction of the wave function. The CSL model has been applied to the inflationary universe before and different conclusions have been obtained. In this letter, we use a different approach to implement the CSL model during inflation. In particular, in addition to accounting for the quantum-to-classical transition, we use the CSL model to generate the primordial perturbations, that is, the dynamical evolution provided by the CSL model is responsible for the transition from a homogeneous and isotropic initial state to a final one lacking such symmetries. Our approach leads to results that can be clearly distinguished from preceding works. Specifically, the scalar and tensor power spectra are not time-dependent, and one retains the amplification mechanism of the CSL model. Moreover, our framework depends only on one parameter (the CSL parameter) and its value is consistent with cosmological and laboratory observations. (orig.)

  6. Emergence of inflationary perturbations in the CSL model

    Energy Technology Data Exchange (ETDEWEB)

    Leon, Gabriel [Universidad de Buenos Aires, Ciudad Universitaria-PabI, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Bengochea, Gabriel R. [Instituto de Astronomia y Fisica del Espacio (IAFE), UBA-CONICET, Buenos Aires (Argentina)

    2016-01-15

    The inflationary paradigm is the most successful model that explains the observed spectrum of primordial perturbations. However, the precise emergence of such inhomogeneities and the quantum-to-classical transition of the perturbations has not yet reached a consensus among the community. The continuous spontaneous localization model (CSL), in the cosmological context, might be used to provide a solution to the mentioned issues by considering a dynamical reduction of the wave function. The CSL model has been applied to the inflationary universe before and different conclusions have been obtained. In this letter, we use a different approach to implement the CSL model during inflation. In particular, in addition to accounting for the quantum-to-classical transition, we use the CSL model to generate the primordial perturbations, that is, the dynamical evolution provided by the CSL model is responsible for the transition from a homogeneous and isotropic initial state to a final one lacking such symmetries. Our approach leads to results that can be clearly distinguished from preceding works. Specifically, the scalar and tensor power spectra are not time-dependent, and one retains the amplification mechanism of the CSL model. Moreover, our framework depends only on one parameter (the CSL parameter) and its value is consistent with cosmological and laboratory observations. (orig.)

  7. The Berne Model and Advertising Messages: A Psychographic Study.

    Science.gov (United States)

    Martin, Charles H.

    This study relates Eric Berne's theory of Transactional Analysis to the effectiveness of advertising messages. A 30 item Personality Mode Test was constructed in order to assess subject agreement with statements reflecting Berne's three personality states: parent (social evaluative), adult (controlled rationality), and child (emotiveness). After…

  8. Developing International Attack Strategy: the Case of Smartcard Expansion at PT CSL

    OpenAIRE

    Hidayah, Taufiqul; Toha, Mohamad

    2013-01-01

    PT CSL is the biggest smartcard manufacturer in Indonesia which has occupied more than 50% of domestic market share. CSL should expand its market abroad to avoid from KPPU regulation related with monopolistic. For competing with global competitors, CSL should position its products and solutions among global manufacturers. CSL should have appropriate attack strategy while entering certain market/segment to fight with existing competitors. Both strategies must be supported International corpora...

  9. Verwaltungsorganisation und politische Partizipation in einer fusionierten Grossstadt Bern

    OpenAIRE

    Sager, Fritz; Frey, Anna Barbara; Kaufmann, David; Wittwer, Stefan

    2017-01-01

    Der vorliegende Bericht wurde im Auftrag des Vereins „Bern NEU Gründen“ durch das Kompetenzzentrum für Public Management der Universität Bern erstellt. Der Bericht zeigt Möglichkeiten auf, wie zentrale Aspekte des politisch-administrativen Systems im Falle eines Zusammenschlusses von zwölf Gemeinden der Stadtregion Bern ausgestaltet werden könnten. Der Bericht ist in zwei Teile aufgeteilt. Im ersten Teil des Berichts wird analysiert, wie eine effektive und effiziente Umsetzung der Verwaltu...

  10. The Effects of 3D Immersion on CSL Students' Listening Comprehension

    Science.gov (United States)

    Lan, Yu-Ju; Liao, Chia-Ying

    2018-01-01

    The study aimed at enhancing Chinese as a second language (CSL) students' listening comprehension by using authentic contexts in Second Life (SL). Twenty-seven CSL students from 4 countries participated in the 6-week study. A within-subject design was adopted to confirm the effects of 3D immersive experiences on CSL students' listening…

  11. Using CSL with Special Education and Reading Resource Students.

    Science.gov (United States)

    Ellis, Barbara Carter

    1993-01-01

    Describes the experiences of an elementary school resource room teacher in Staten Island (New York) in using community service learning (CSL) with special education and reading resource students. Students planned and carried out a cupcake sale to benefit UNICEF. Parent participation was an important part of the process. (SLD)

  12. Technology evaluation: HPV vaccine (quadrivalent), Aventis Pasteur MSD/CSL.

    Science.gov (United States)

    Reinis, Milan

    2004-04-01

    CSL, licensee of UniQuest's HPV technology, and Aventis Pasteur MSD (a joint venture between Merck & Co and Aventis) are jointly developing a vaccine for the potential prophylaxis of genital warts and cervical cancer caused by human papilloma virus infection. Enrollment for a phase III trial has been completed.

  13. Bern-Kosower rule for scalar QED

    International Nuclear Information System (INIS)

    Daikouji, K.; Shino, M.; Sumino, Y.

    1996-01-01

    We derive a full Bern-Kosower-type rule for scalar QED starting from quantum field theory: we derive a set of rules for calculating S-matrix elements for any processes at any order of the coupling constant. A gauge-invariant set of diagrams in general is first written in the world line path-integral expression. Then we integrate over x(τ), and the resulting expression is given in terms of a correlation function on the world line left-angle x(τ)x(τ ' )right-angle. Simple rules to decompose the correlation function into basic elements are obtained. A gauge transformation known as the integration by parts technique can be used to reduce the number of independent terms before integration over proper-time variables. The surface terms can be omitted provided the external scalars are on shell. Also, we clarify correspondence to the conventional Feynman rule, which enabled us to avoid any ambiguity coming from the infinite dimensionality of the path-integral approach. copyright 1996 The American Physical Society

  14. Dissecting and circumventing the requirement for RAM in CSL-dependent Notch signaling.

    Directory of Open Access Journals (Sweden)

    Scott E Johnson

    Full Text Available The Notch signaling pathway is an intercellular communication network vital to metazoan development. Notch activation leads to the nuclear localization of the intracellular portion (NICD of the Notch receptor. Once in the nucleus, NICD binds the transcription factor CSL through a bivalent interaction involving the high-affinity RAM region and the lower affinity ANK domain, converting CSL from a transcriptionally-repressed to an active state. This interaction is believed to directly displace co-repressor proteins from CSL and recruit co-activator proteins. Here we investigate the consequences of this bivalent organization in converting CSL from the repressed to active form. One proposed function of RAM is to promote the weak ANK:CSL interaction; thus, fusion of CSL-ANK should bypass this function of RAM. We find that a CSL-ANK fusion protein is transcriptionally active in reporter assays, but that the addition of RAM in trans further increases transcriptional activity, suggesting another role of RAM in activation. A single F235L point substitution, which disrupts co-repressor binding to CSL, renders the CSL-ANK fusion fully active and refractory to further stimulation by RAM in trans. These results suggest that in the context of a mammalian CSL-ANK fusion protein, the main role of RAM is to displace co-repressor proteins from CSL.

  15. Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells

    Directory of Open Access Journals (Sweden)

    Eike-Benjamin Braune

    2016-05-01

    Full Text Available Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL, and hyperactivated Notch signaling is associated with tumor development; thus it may be anticipated that CSL deficiency should reduce tumor growth. In contrast, we report that genetic removal of CSL in breast tumor cells caused accelerated growth of xenografted tumors. Loss of CSL unleashed a hypoxic response during normoxic conditions, manifested by stabilization of the HIF1α protein and acquisition of a polyploid giant-cell, cancer stem cell-like, phenotype. At the transcriptome level, loss of CSL upregulated more than 1,750 genes and less than 3% of those genes were part of the Notch transcriptional signature. Collectively, this suggests that CSL exerts functions beyond serving as the central node in the Notch signaling cascade and reveals a role for CSL in tumorigenesis and regulation of the cellular hypoxic response.

  16. The Role of Morphological Awareness in the Incidental Learning of Chinese Characters among CSL Learners

    Science.gov (United States)

    Zhang, Yanhui; Li, Ruyu

    2016-01-01

    This study investigates the role of morphological awareness in the incidental learning of Mandarin Chinese characters among Chinese as second language (CSL) learners. Participants of the study were 20 college-level international students, uniformly Thai in language background, enrolled to study CSL at Southwest University, Chongqing, China. The…

  17. Quasi-matter bounce and inflation in the light of the CSL model

    International Nuclear Information System (INIS)

    Leon, Gabriel; Bengochea, Gabriel R.; Landau, Susana J.

    2016-01-01

    The continuous spontaneous localization (CSL) model has been proposed as a possible solution to the quantum measurement problem by modifying the Schroedinger equation. In this work, we apply the CSL model to two cosmological models of the early Universe: the matter bounce scenario and slow roll inflation. In particular, we focus on the generation of the classical primordial inhomogeneities and anisotropies that arise from the dynamical evolution, provided by the CSL mechanism, of the quantum state associated to the quantum fields. In each case, we obtained a prediction for the shape and the parameters characterizing the primordial spectra (scalar and tensor), i.e. the amplitude, the spectral index and the tensor-to-scalar ratio. We found that there exist CSL parameter values, allowed by other non-cosmological experiments, for which our predictions for the angular power spectrum of the CMB temperature anisotropy are consistent with the best fit canonical model to the latest data released by the Planck Collaboration. (orig.)

  18. Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis.

    Science.gov (United States)

    Zeng, Chong; Xing, Rui; Liu, Jing; Xing, Feiyue

    2016-01-01

    Apoptosis is a normally biological phenomenon in various organisms, involving complexly molecular mechanisms with a series of signaling processes. Notch signaling is found evolutionarily conserved in many species, playing a critical role in embryonic development, normal tissue homeostasis, angiogenesis and immunoregulation. The focus of this review is on currently novel advances about roles of CSL-dependent and independent Notch signaling pathways in cell apoptosis. The CSL can bind Notch intracellular domain (NIC) to act as a switch in mediating transcriptional activation or inactivation of the Notch signaling pathway downstream genes in the nucleus. It shows that CSL-dependent signaling regulates the cell apoptosis through Hes-1-PTEN-AKT-mTOR signaling, but rather the CSL-independent signaling mediates the cell apoptosis possibly via NIC-mTORC2-AKT-mTOR signaling, providing a new insight into apoptotic mechanisms.

  19. Role of Culture in the Acquisition of CSL – From the Perspective of Intercultural Communication Competence

    OpenAIRE

    Ip, Wei Hing

    2015-01-01

    In the past few decades, the demands for coping with the rapid development of information communication technology, internationalization and globalization worldwide have shifted the focus of Chinese as a second language (CSL) towards intercultural communication competence in which the role of culture in the acquisition of CSL and in the pragmatic use of the language is emphasized and promoted. However, most of the present research in this academic area still remains only on a theoretical leve...

  20. Frontiers in Medicinal Chemistry 2017 in Bern, Switzerland.

    Science.gov (United States)

    Probst, Daniel; Heitz, Marc; Poirier, Marion; Gan, Bee Ha; Delalande, Clémence; Reymond, Jean-Louis

    2017-10-09

    Sharing capital ideas: The 2017 Frontiers in Medicinal Chemistry (FiMC) conference, organized jointly by the German Chemical Society, the German Pharmaceutical Society, and the Swiss Chemical Society, was held at the Department of Chemistry and Biochemistry of the University of Bern in February 2017. Herein we summarize the many conference highlights, and look forward to the next FiMC meeting, to be held in Jena (Germany) in March 2018. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. The cyclotron laboratory and the RFQ accelerator in Bern

    Science.gov (United States)

    Braccini, S.; Ereditato, A.; Kreslo, I.; Nirkko, M.; Scampoli, P.; von Bremen, K.; Weber, M.

    2013-07-01

    Two proton accelerators have been recently put in operation in Bern: an 18 MeV cyclotron and a 2 MeV RFQ linac. The commercial IBA 18/18 cyclotron, equipped with a specifically conceived 6 m long external beam line ending in a separate bunker, will provide beams for routine 18-F and other PET radioisotope production as well as for novel detector, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. The accelerator is embedded into a complex building hosting two physics laboratories and four Good Manufacturing Practice (GMP) laboratories. This project is the result of a successful collaboration between the Inselspital, the University of Bern and private investors, aiming at the constitution of a combined medical and research centre able to provide the most cutting-edge technologies in medical imaging and cancer radiation therapy. The cyclotron is complemented by the RFQ with the primary goals of elemental analysis via Particle Induced Gamma Emission (PIGE), and the detection of potentially dangerous materials with high nitrogen content using the Gamma-Resonant Nuclear Absorption (GRNA) technique. In this context, beam instrumentation devices have been developed, in particular an innovative beam profile monitor based on doped silica fibres and a setup for emittance measurements using the pepper-pot technique. On this basis, the establishment of a proton therapy centre on the campus of the Inselspital is in the phase of advanced study.

  2. The cyclotron laboratory and the RFQ accelerator in Bern

    International Nuclear Information System (INIS)

    Braccini, S.; Ereditato, A.; Kreslo, I.; Nirkko, M.; Weber, M.; Scampoli, P.; Bremen, K. von

    2013-01-01

    Two proton accelerators have been recently put in operation in Bern: an 18 MeV cyclotron and a 2 MeV RFQ linac. The commercial IBA 18/18 cyclotron, equipped with a specifically conceived 6 m long external beam line ending in a separate bunker, will provide beams for routine 18-F and other PET radioisotope production as well as for novel detector, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. The accelerator is embedded into a complex building hosting two physics laboratories and four Good Manufacturing Practice (GMP) laboratories. This project is the result of a successful collaboration between the Inselspital, the University of Bern and private investors, aiming at the constitution of a combined medical and research centre able to provide the most cutting-edge technologies in medical imaging and cancer radiation therapy. The cyclotron is complemented by the RFQ with the primary goals of elemental analysis via Particle Induced Gamma Emission (PIGE), and the detection of potentially dangerous materials with high nitrogen content using the Gamma-Resonant Nuclear Absorption (GRNA) technique. In this context, beam instrumentation devices have been developed, in particular an innovative beam profile monitor based on doped silica fibres and a setup for emittance measurements using the pepper-pot technique. On this basis, the establishment of a proton therapy centre on the campus of the Inselspital is in the phase of advanced study

  3. Shear viscosity of binary mixtures: The Gay–Berne potential

    International Nuclear Information System (INIS)

    Khordad, R.

    2012-01-01

    Highlights: ► Most useful potential model to study the real systems is the Gay–Berne (GB) potential. ► We use GB model to examine thermodynamical properties of some anisotropic binary mixtures in two different phases. ► The integral equation methods are applied to solve numerically the Percus–Yevick (PY) equation. ► We obtain expansion coefficients of correlation functions needed to calculate the properties of studied mixtures. ► The results are compared with the available experimental data [e.g., HFC-125 + propane, R-125/143a, methanol + toluene, etc.] - Abstract: The Gay–Berne (GB) potential model is an interesting and useful model to study the real systems. Using the potential model, we intend to examine the thermodynamical properties of some anisotropic binary mixtures in two different phases, liquid and gas. For this purpose, we apply the integral equation method and solve numerically the Percus–Yevick (PY) integral equation. Then, we obtain the expansion coefficients of correlation functions to calculate the thermodynamical properties. Finally, we compare our results with the available experimental data [e.g., HFC-125 + propane, R-125/143a, methanol + toluene, benzene + methanol, cyclohexane + ethanol, benzene + ethanol, carbon tetrachloride + ethyl acetate, and methanol + ethanol]. The results show that the GB potential model is capable for predicting the thermodynamical properties of binary mixtures with acceptable accuracy.

  4. The cyclotron laboratory and the RFQ accelerator in Bern

    Energy Technology Data Exchange (ETDEWEB)

    Braccini, S.; Ereditato, A.; Kreslo, I.; Nirkko, M.; Weber, M. [Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern (Switzerland); Scampoli, P. [Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland and Department of Physical Sciences, University Federico II, Via Cintia, I-60126 Napoli (Italy); Bremen, K. von [SWAN Isotopen AG, Inselspital, CH-3010 Bern (Switzerland)

    2013-07-18

    Two proton accelerators have been recently put in operation in Bern: an 18 MeV cyclotron and a 2 MeV RFQ linac. The commercial IBA 18/18 cyclotron, equipped with a specifically conceived 6 m long external beam line ending in a separate bunker, will provide beams for routine 18-F and other PET radioisotope production as well as for novel detector, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. The accelerator is embedded into a complex building hosting two physics laboratories and four Good Manufacturing Practice (GMP) laboratories. This project is the result of a successful collaboration between the Inselspital, the University of Bern and private investors, aiming at the constitution of a combined medical and research centre able to provide the most cutting-edge technologies in medical imaging and cancer radiation therapy. The cyclotron is complemented by the RFQ with the primary goals of elemental analysis via Particle Induced Gamma Emission (PIGE), and the detection of potentially dangerous materials with high nitrogen content using the Gamma-Resonant Nuclear Absorption (GRNA) technique. In this context, beam instrumentation devices have been developed, in particular an innovative beam profile monitor based on doped silica fibres and a setup for emittance measurements using the pepper-pot technique. On this basis, the establishment of a proton therapy centre on the campus of the Inselspital is in the phase of advanced study.

  5. Expression profiling and integrative analysis of the CESA/CSL superfamily in rice

    Directory of Open Access Journals (Sweden)

    Tu Yuanyuan

    2010-12-01

    Full Text Available Abstract Background The cellulose synthase and cellulose synthase-like gene superfamily (CESA/CSL is proposed to encode enzymes for cellulose and non-cellulosic matrix polysaccharide synthesis in plants. Although the rice (Oryza sativa L. genome has been sequenced for a few years, the global expression profiling patterns and functions of the OsCESA/CSL superfamily remain largely unknown. Results A total of 45 identified members of OsCESA/CSL were classified into two clusters based on phylogeny and motif constitution. Duplication events contributed largely to the expansion of this superfamily, with Cluster I and II mainly attributed to tandem and segmental duplication, respectively. With microarray data of 33 tissue samples covering the entire life cycle of rice, fairly high OsCESA gene expression and rather variable OsCSL expression were observed. While some members from each CSL family (A1, C9, D2, E1, F6 and H1 were expressed in all tissues examined, many of OsCSL genes were expressed in specific tissues (stamen and radicles. The expression pattern of OsCESA/CSL and OsBC1L which extensively co-expressed with OsCESA/CSL can be divided into three major groups with ten subgroups, each showing a distinct co-expression in tissues representing typically distinct cell wall constitutions. In particular, OsCESA1, -3 & -8 and OsCESA4, -7 & -9 were strongly co-expressed in tissues typical of primary and secondary cell walls, suggesting that they form as a cellulose synthase complex; these results are similar to the findings in Arabidopsis. OsCESA5/OsCESA6 is likely partially redundant with OsCESA3 for OsCESA complex organization in the specific tissues (plumule and radicle. Moreover, the phylogenetic comparison in rice, Arabidopsis and other species can provide clues for the prediction of orthologous gene expression patterns. Conclusions The study characterized the CESA/CSL of rice using an integrated approach comprised of phylogeny, transcriptional

  6. BFKL Pomeron, Reggeized gluons and Bern-Dixon-Smirnov amplitudes

    CERN Document Server

    Bartels, J; Sabio Vera, Agustin

    2009-01-01

    After a brief review of the BFKL approach to Regge processes in QCD and in supersymmetric (SUSY) gauge theories we propose a strategy for calculating the next-to-next-to-leading order corrections to the BFKL kernel. They can be obtained in terms of various cross-sections for Reggeized gluon interactions. The corresponding amplitudes can be calculated in the framework of the effective action for high energy scattering. In the case of N=4 SUSY it is also possible to use the Bern-Dixon-Smirnov (BDS) ansatz. For this purpose the analytic properties of the BDS amplitudes at high energies are investigated, in order to verify their self-consistency. It is found that, for the number of external particles being larger than five, these amplitudes, beyond one loop, are not in agreement with the BFKL approach which predicts the existence of Regge cuts in some physical channels.

  7. New bern biomass to energy project Phase I: Feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Parson, F.; Bain, R.

    1995-10-01

    Weyerhaeuser, together with Amoco and Carolina Power & Light, performed a detailed evaluation of biomass gasification and enzymatic processing of biomass to ethanol. This evaluation assesses the potential of these technologies for commercial application to determine which technology offers the best opportunity at this time to increase economic productivity of forest resources in an environmentally sustainable manner. The work performed included preparation of site-specific plant designs that integrate with the Weyerhaeuser New Bern, North Carolina pulp mill to meet overall plant energy requirements, cost estimates, resource and product market assessments, and technology evaluations. The Weyerhaeuser team was assisted by Stone & Webster Engineering Corporation and technology vendors in developing the necessary data, designs, and cost information used in this comparative study. Based on the information developed in this study and parallel evaluations performed by Weyerhaeuser and others, biomass gasification for use in power production appears to be technically and economically viable. Options exist at the New Bern mill which would allow commercial scale demonstration of the technology in a manner that would serve the practical energy requirements of the mill. A staged project development plan has been prepared for review. The plan would provide for a low-risk and cost demonstration of a biomass gasifier as an element of a boiler modification program and then allow for timely expansion of power production by the addition of a combined cycle cogeneration plant. Although ethanol technology is at an earlier stage of development, there appears to be a set of realizable site and market conditions which could provide for an economically attractive woody-biomass-based ethanol facility. The market price of ethanol and the cost of both feedstock and enzyme have a dramatic impact on the projected profitability of such a plant.

  8. ??? - Bern 1935 - Tartu 1995 : [Protokolõ sionskihh mudretsov] / Kristiina Ross ; ter.: Majana Abramson

    Index Scriptorium Estoniae

    Ross, Kristiina, 1955-

    1996-01-01

    Sisu: Tartu 1995; 'Protokolõ' kak takovõje; Original 'Protokolov'; Predõstorija sozdanija mifa o pokorenii mira jevrejami - volnõmi kamenshtshikami; 'Protokolõ' v ideologitsheskom hodu; 'Protokolõ' i natsism; Bern 1935-1937

  9. In Bern high-energy physics shares proton beams with the hospital

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    A joint venture bringing together public institutions and private companies is building a new facility on the campus of Inselspital, Bern’s university hospital. The facility will host a cyclotron for the production of radiopharmaceuticals for use in PET as well as in multidisciplinary research laboratories for the development of new products for medical imaging. The Laboratory for High Energy Physics (LHEP) of Bern University, which is deeply involved in the project, will have access to a dedicated beam line and specialized labs.     Construction of the new facility is ongoing at Bern's University Hospital, where the cyclotron will be installed.   The first Bern Cyclotron symposium will take place on 6 and 7 June this year. The event is being organised by LHEP in collaboration with Bern’s Inselspital and will bring together experts – including several from CERN – to promote research activities at the new Bern Cyclotron Laboratory. &ld...

  10. Evaluating CSL/CFL Website Usability: A User-Centered Design Approach

    Science.gov (United States)

    Huang, Chung-Kai; Hsin, Ching-O; Chiu, Chiung-Hui

    2010-01-01

    With the widespread availability of Internet and computer technology, on-line web-based learning has become prevalent in the field of teaching Chinese as a second/foreign language (CSL/CFL). This study examined the concepts of usability and types of design elements that help construct an effective web-based learning environment, as well as their…

  11. CSL protein regulates transcription of genes required to prevent catastrophic mitosis in fission yeast.

    Science.gov (United States)

    Převorovský, Martin; Oravcová, Martina; Zach, Róbert; Jordáková, Anna; Bähler, Jürg; Půta, František; Folk, Petr

    2016-11-16

    For every eukaryotic cell to grow and divide, intricately coordinated action of numerous proteins is required to ensure proper cell-cycle progression. The fission yeast Schizosaccharomyces pombe has been instrumental in elucidating the fundamental principles of cell-cycle control. Mutations in S. pombe 'cut' (cell untimely torn) genes cause failed coordination between cell and nuclear division, resulting in catastrophic mitosis. Deletion of cbf11, a fission yeast CSL transcription factor gene, triggers a 'cut' phenotype, but the precise role of Cbf11 in promoting mitotic fidelity is not known. We report that Cbf11 directly activates the transcription of the acetyl-coenzyme A carboxylase gene cut6, and the biotin uptake/biosynthesis genes vht1 and bio2, with the former 2 implicated in mitotic fidelity. Cbf11 binds to a canonical, metazoan-like CSL response element (GTGGGAA) in the cut6 promoter. Expression of Cbf11 target genes shows apparent oscillations during the cell cycle using temperature-sensitive cdc25-22 and cdc10-M17 block-release experiments, but not with other synchronization methods. The penetrance of catastrophic mitosis in cbf11 and cut6 mutants is nutrient-dependent. We also show that drastic decrease in biotin availability arrests cell proliferation but does not cause mitotic defects. Taken together, our results raise the possibility that CSL proteins play conserved roles in regulating cell-cycle progression, and they could guide experiments into mitotic CSL functions in mammals.

  12. The Graduate School of Climate Sciences, University of Bern

    Science.gov (United States)

    Martin, L.

    2012-04-01

    The Graduate School of Climate Sciences, University of Bern, offers a specialised M.Sc. and a Ph.D. study programme in climate sciences. The graduate school has a highly interdisciplinary profile involving not only natural sciences, but also humanities/history, economics and law. The ten participating institutes with a total of 45 academics provide expertise in long-term climate variability, climate modelling, climate reconstruction, predictability of the future climate and extreme events, the impact of climate change on ecosystems and climate risks for society and economy. The graduate school is fully compliant with the Bologna Accords and collaborates closely with the sister institution C2SM at ETH Zurich by, e.g., jointly organised lectures. There are currently 23 master and 37 doctoral students in the programme. These originate from the University of Bern (28 %), from other Swiss universities (30 %) and from foreign universities (42 %). Comprehensive information about the Graduate School of Climate Sciences is available at http://www.climatestudies.unibe.ch . The M.Sc. in Climate Sciences programme (120 ECTS credits) is designed to attract students from all disciplines in natural sciences and offers them a tailor-made curriculum to reach their career aspirations. The students make their own course selection according to their profile envisaged (specialised versus broad education) and ideally already guided by a job perspective. Selecting the courses and the topic of the master thesis they specialise in one of five fields: climate and earth system science; atmospheric science; economics; economic, social and environmental history; statistics. Several courses are organised jointly with public authorities and the private industry, e.g. from experts working in the insurance business, in weather forecasting or in environmental pollution control. This provides the students hands-on experience and contacts to future employers. The master thesis (60 ECTS) involves the

  13. Genome-wide analysis of the cellulose synthase-like (Csl) gene family in bread wheat (Triticum aestivum L.).

    Science.gov (United States)

    Kaur, Simerjeet; Dhugga, Kanwarpal S; Beech, Robin; Singh, Jaswinder

    2017-11-03

    Hemicelluloses are a diverse group of complex, non-cellulosic polysaccharides, which constitute approximately one-third of the plant cell wall and find use as dietary fibres, food additives and raw materials for biofuels. Genes involved in hemicellulose synthesis have not been extensively studied in small grain cereals. In efforts to isolate the sequences for the cellulose synthase-like (Csl) gene family from wheat, we identified 108 genes (hereafter referred to as TaCsl). Each gene was represented by two to three homeoalleles, which are named as TaCslXY_ZA, TaCslXY_ZB, or TaCslXY_ZD, where X denotes the Csl subfamily, Y the gene number and Z the wheat chromosome where it is located. A quarter of these genes were predicted to have 2 to 3 splice variants, resulting in a total of 137 putative translated products. Approximately 45% of TaCsl genes were located on chromosomes 2 and 3. Sequences from the subfamilies C and D were interspersed between the dicots and grasses but those from subfamily A clustered within each group of plants. Proximity of the dicot-specific subfamilies B and G, to the grass-specific subfamilies H and J, respectively, points to their common origin. In silico expression analysis in different tissues revealed that most of the genes were expressed ubiquitously and some were tissue-specific. More than half of the genes had introns in phase 0, one-third in phase 2, and a few in phase 1. Detailed characterization of the wheat Csl genes has enhanced the understanding of their structural, functional, and evolutionary features. This information will be helpful in designing experiments for genetic manipulation of hemicellulose synthesis with the goal of developing improved cultivars for biofuel production and increased tolerance against various stresses.

  14. N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast.

    Directory of Open Access Journals (Sweden)

    Martin Převorovský

    Full Text Available CSL (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1 transcription factors are the effector components of the Notch receptor signalling pathway, which is critical for metazoan development. The metazoan CSL proteins (class M can also function in a Notch-independent manner. Recently, two novel classes of CSL proteins, designated F1 and F2, have been identified in fungi. The role of the fungal CSL proteins is unclear, because the Notch pathway is not present in fungi. In fission yeast, the Cbf11 and Cbf12 CSL paralogs play antagonistic roles in cell adhesion and the coordination of cell and nuclear division. Unusually long N-terminal extensions are typical for fungal and invertebrate CSL family members. In this study, we investigate the functional significance of these extended N-termini of CSL proteins.We identify 15 novel CSL family members from 7 fungal species and conduct bioinformatic analyses of a combined dataset containing 34 fungal and 11 metazoan CSL protein sequences. We show that the long, non-conserved N-terminal tails of fungal CSL proteins are likely disordered and enriched in phosphorylation sites and PEST motifs. In a case study of Cbf12 (class F2, we provide experimental evidence that the protein is proteolytically processed and that the N-terminus inhibits the Cbf12-dependent DNA binding activity in an electrophoretic mobility shift assay.This study provides insight into the characteristics of the long N-terminal tails of fungal CSL proteins that may be crucial for controlling DNA-binding and CSL function. We propose that the regulation of DNA binding by Cbf12 via its N-terminal region represents an important means by which fission yeast strikes a balance between the class F1 and class F2 paralog activities. This mode of regulation might be shared with other CSL-positive fungi, some of which are relevant to human disease and biotechnology.

  15. Effects of Lactobacillus acidophilus D2/CSL on laying hen performance

    Directory of Open Access Journals (Sweden)

    Luigi Guidobono Cavalchini

    2010-01-01

    Full Text Available In order to evaluate the effects of dietary addition of probiotic strain Lactobacillus acidophilus D2/CSL on hen performance and egg quality, 160 commercial Hy-Line Brown pullets, 17 weeks old, were divided in control group (C (N=80 and treated group (T (N=80, with 4 alternate replicates of 20 animals each per group. C was fed with a “standard diet”, whereas the T group received the same diet with an inclusion of 1x109 CFU kg-1 of Lactobacillus acidophilus D2/CSL (freeze dried cells. The experimental trial lasted 39 weeks after one week of acclimatization. Hen performance and egg quality (egg production, FCR, egg specific gravity, shell thickness, Haugh Units were recorded. The results show a higher overall egg production (P<0.01 and better FCR (Kg feed intake/Kg saleable eggs (P<0.05 in the T birds, but no statistically significant differences were observed in egg weight. The eggs from the T birds were characterized by a higher specific gravity (ESG (P<0.01 and albumen viscosity (Haugh Units (P<0.05. No significant differences in egg shell thickness were recorded. In conclusion, Lactobacillus acidophilus D2/CSL improved some important parameters in laying hen performance and egg quality.

  16. Investigation into the temperature dependence of isotropic- nematic phase transition of Gay- Berne liquid crystals

    Directory of Open Access Journals (Sweden)

    A Avazpour

    2014-12-01

    Full Text Available Density functional approach was used to study the isotropic- nematic (I-N transition and calculate the values of freezing parameters of the Gay- Berne liquid crystal model. New direct and pair correlation functions of a molecular fluid with Gay- Berne pair potential were used. These new functions were used in density functional theory as input to calculate the isotropic- nematic transition densities for elongation at various reduced temperatures. It was observed that the isotropic- nematic transition densities increase as the temperature increases. It was found that the new direct correlation function is suitable to study the isotropic- nematic transition of Gay- Berne liquids. Comparison to other works showed qualitative agreement

  17. Influence of pore shape on the structure of a nanoconfined Gay-Berne liquid crystal

    Science.gov (United States)

    Ji, Qing; Lefort, Ronan; Morineau, Denis

    2009-08-01

    We present results from molecular dynamics simulations of a Gay-Berne mesogenic system GB(4.4,20,1,1) under short scale spatial confinement in a slab, a cylinder and a sphere geometry. The structure adopted by the confined phases is characterized by the density profile and the orientational order parameter as a function of temperature, and compared to the bulk. Though confinement always induces a strong surface ordering, the topological constrain introduced by the different pore shapes results in different molecular arrangements. This first study on pore shape effect on the structure of a nanoconfined Gay-Berne system is relevant to numerous experimental studies performed with different mesoporous matrices.

  18. Technology transfer in the energy domain in the Canton of Berne. Evaluation 1996. Final Report; Technologievermittlung im Energiebereich des Kantons Bern. Begleitende Evaluation 1996. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Meier, R.; Schaerer, H.U.; Jakob, E.; Kriesi, R.; Spahr, I.; Schaefer, H.; Kuster, J.

    1996-12-01

    The Canton of Bern has promoted the transfer of technology since 1993. Together with the Department of Energy Economy, it began a pilot project in this field in 1995. An energy expert from the private sector was given the task of building up contacts between the energy research and industry. In this report, an independent expert evaluates this pilot project as positive and recommends its continuation. (author) figs., tabs., 10 refs.

  19. Prediction of filamentous process performance attributes by CSL quality assessment using mid-infrared spectroscopy and chemometrics.

    Science.gov (United States)

    Hofer, Alexandra; Kamravamanesh, Donya; Bona-Lovasz, Judit; Limbeck, Andreas; Lendl, Bernhard; Herwig, Christoph; Fricke, Jens

    2018-01-10

    Every biopharmaceutical production process aims for control strategies to achieve process robustness in order to ensure consistent product quality. Process variability can origin from process parameters, the biological nature as well as from high lot-to-lot variability of raw materials. In filamentous processes raw materials with very complex matrices, such as corn steep liquor (CSL), are used, which are especially challenging to characterize. In this study, CSL was characterized in detail for its ingredients presenting an overall composition of its matrix of 50 analyzed components (19 amino acids, 5 organic acids, 8 reducing sugars, 7 water-soluble vitamins and 11 trace elements/minerals) in order to facilitate analytical reduction to fingerprinting methods FT-MIR was evaluated as fast and non-destructive spectroscopic fingerprinting method for adequate assessment of CSL quality. Feasibility of this method was shown by the correlation of certain bands in the spectra to substance groups present in CSL, such as the Amide I and II band and amino acids, respectively. Additionally, applicability of FT-MIR could be shown for classification of different CSL lots differing in provider and corn quality as well as for predictability of process performance attributes. The latter was demonstrated on a fed-batch filamentous fungi process for the production of antibiotics. By multivariate data analysis, it could be shown that CSL quality assessment via FT-MIR can be used for the prediction of maximal biomass generated in the process, with a correlation coefficient R 2 of 0.964, as well as for the prediction of an unwanted impurity. The combination of a fast and easy method for CSL quality assessment and correlations of this quality with process performance attributes may facilitate the establishment of a risk-based acceptance criteria for raw material quality release of CSL. As CSL is a frequent used raw material, we believe that this method will also be useful for other

  20. Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division

    Energy Technology Data Exchange (ETDEWEB)

    Prevorovsky, Martin; Grousl, Tomas; Stanurova, Jana; Rynes, Jan [Department of Cell Biology, Faculty of Science, Charles University in Prague, Vinicna 7, 128 43, Prague 2 (Czech Republic); Nellen, Wolfgang [Department of Genetics, Kassel University, Heinrich Plett Strasse 40, 34132 Kassel (Germany); Puta, Frantisek [Department of Cell Biology, Faculty of Science, Charles University in Prague, Vinicna 7, 128 43, Prague 2 (Czech Republic); Folk, Petr, E-mail: folk@natur.cuni.cz [Department of Cell Biology, Faculty of Science, Charles University in Prague, Vinicna 7, 128 43, Prague 2 (Czech Republic)

    2009-05-01

    The CSL (CBF1/RBP-J{kappa}/Suppressor of Hairless/LAG-1) family is comprised of transcription factors essential for metazoan development, mostly due to their involvement in the Notch receptor signaling pathway. Recently, we identified two novel classes of CSL genes in the genomes of several fungal species, organisms lacking the Notch pathway. In this study, we characterized experimentally cbf11{sup +} and cbf12{sup +}, the two CSL genes of Schizosaccharomyces pombe, in order to elucidate the CSL function in fungi. We provide evidence supporting their identity as genuine CSL genes. Both cbf11{sup +} and cbf12{sup +} are non-essential; they have distinct expression profiles and code for nuclear proteins with transcription activation potential. Significantly, we demonstrated that Cbf11 recognizes specifically the canonical CSL response element GTG{sup A}/{sub G}GAA in vitro. The deletion of cbf11{sup +} is associated with growth phenotypes and altered colony morphology. Furthermore, we found that Cbf11 and Cbf12 play opposite roles in cell adhesion, nuclear and cell division and their coordination. Disturbed balance of the two CSL proteins leads to cell separation defects (sep phenotype), cut phenotype, and high-frequency diploidization in heterothallic strains. Our data show that CSL proteins operate in an organism predating the Notch pathway, which should be of relevance to the understanding of (Notch-independent) CSL functions in metazoans.

  1. Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division

    International Nuclear Information System (INIS)

    Prevorovsky, Martin; Grousl, Tomas; Stanurova, Jana; Rynes, Jan; Nellen, Wolfgang; Puta, Frantisek; Folk, Petr

    2009-01-01

    The CSL (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) family is comprised of transcription factors essential for metazoan development, mostly due to their involvement in the Notch receptor signaling pathway. Recently, we identified two novel classes of CSL genes in the genomes of several fungal species, organisms lacking the Notch pathway. In this study, we characterized experimentally cbf11 + and cbf12 + , the two CSL genes of Schizosaccharomyces pombe, in order to elucidate the CSL function in fungi. We provide evidence supporting their identity as genuine CSL genes. Both cbf11 + and cbf12 + are non-essential; they have distinct expression profiles and code for nuclear proteins with transcription activation potential. Significantly, we demonstrated that Cbf11 recognizes specifically the canonical CSL response element GTG A / G GAA in vitro. The deletion of cbf11 + is associated with growth phenotypes and altered colony morphology. Furthermore, we found that Cbf11 and Cbf12 play opposite roles in cell adhesion, nuclear and cell division and their coordination. Disturbed balance of the two CSL proteins leads to cell separation defects (sep phenotype), cut phenotype, and high-frequency diploidization in heterothallic strains. Our data show that CSL proteins operate in an organism predating the Notch pathway, which should be of relevance to the understanding of (Notch-independent) CSL functions in metazoans.

  2. 76 FR 72309 - Drawbridge Operation Regulation; Neuse River, New Bern, NC

    Science.gov (United States)

    2011-11-23

    ... bridge across Neuse River, mile 33.7 at New Bern, NC. The drawbridge was replaced with a fixed bridge in... http://www.regulations.gov , inserting USCG-2011-0974 in the ``Keyword'' box, and then clicking... operating regulation at 33 CFR 117.824(a), was removed and replaced with a fixed bridge in 1999. The bridge...

  3. 77 FR 18105 - Drawbridge Operation Regulation; Trent River, New Bern, NC

    Science.gov (United States)

    2012-03-27

    ... Cunningham Bascule Bridge across the Trent River, mile 0.0, at New Bern, NC. The route of the cycle ride... routes to the Neuse River from the Trent River. In accordance with 33 CFR 117.35(e), the drawbridge must...

  4. Randomized trial to compare the safety and immunogenicity of CSL Limited's 2009 trivalent inactivated influenza vaccine to an established vaccine in United States children.

    Science.gov (United States)

    Brady, Rebecca C; Hu, Wilson; Houchin, Vonda G; Eder, Frank S; Jackson, Kenneth C; Hartel, Gunter F; Sawlwin, Daphne C; Albano, Frank R; Greenberg, Michael

    2014-12-12

    A trivalent inactivated influenza vaccine (CSL's TIV, CSL Limited) was licensed under USA accelerated approval regulations for use in persons≥18 years. We performed a randomized, observer-blind study to assess the safety and immunogenicity of CSL's TIV versus an established US-licensed vaccine in a population≥6 months to vaccination history determined the dosing regimen (one or two vaccinations). Subjects received CSL's TIV (n=739) or the established vaccine (n=735) in the autumn of 2009. Serum hemagglutination-inhibition titers were determined pre-vaccination and 30 days after the last vaccination. No febrile seizures or other vaccine-related SAEs were reported. After the first vaccination for Cohorts A and B, respectively, the relative risks of fever were 2.73 and 2.32 times higher for CSL's TIV compared to the established vaccine. Irritability and loss of appetite (for Cohort A) and malaise (for Cohort B) were also significantly higher for CSL's TIV compared to the established vaccine. Post-vaccination geometric mean titers (GMTs) for CSL's TIV versus the established vaccine were 385.49 vs. 382.45 for H1N1; 669.13 vs. 705.61 for H3N2; and 100.65 vs. 93.72 for B. CSL's TIV demonstrated immunological non-inferiority to the established vaccine in all cohorts. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of a health claim related to a combination of Lactobacillus delbrueckii subsp. bulgaricus AY/CSL (LMG P-17224) and Streptococcus thermophilus 9Y/CSL (LMG P-17225) and “beneficial modulation

    DEFF Research Database (Denmark)

    Tetens, Inge

    of a health claim related to a combination of Lactobacillus delbrueckii subsp. bulgaricus AY/CSL (LMG P-17224) and Streptococcus thermophilus 9Y/CSL (LMG P-17225) and “beneficial modulation of intestinal microflora”. The scope of the application was proposed to fall under a health claim referring to children......’s development and health. The food constituent that is the subject of the health claim, a combination of L. delbrueckii subsp. bulgaricus AY/CSL (LMG P-17224) and S. thermophilus 9Y/CSL (LMG P-17225), has not been sufficiently characterised. The claimed effect is “beneficial modulation of the intestinal...... that a cause and effect relationship has not been established between the consumption of the food constituent, the combination of L. delbrueckii subsp. bulgaricus AY/CSL (LMG P-17224) and S. thermophilus 9Y/CSL (LMG P-17225), and a beneficial physiological effect related to “beneficial modulation...

  6. Bacterial infections in horses: a retrospective study at the University Equine Clinic of Bern.

    Science.gov (United States)

    Panchaud, Y; Gerber, V; Rossano, A; Perreten, V

    2010-04-01

    Bacterial infections present a major challenge in equine medicine. Therapy should be based on bacteriological diagnosis to successfully minimize the increasing number of infections caused by multidrug-resistant bacteria. The present study is a retrospective analysis of bacteriological results from purulent infections in horses admitted at the University Equine Clinic of Bern from 2004 to 2008. From 378 samples analyzed, 557 isolates were identified, of which Staphylococcus aureus, Streptococcus equi subsp. zooepidemicus and coliforms were the most common. Special attention was paid to infections with methicillin-resistant S. aureus (MRSA) ST398 and a non-MRSA, multidrug-resistant S. aureus clone ST1 (BERN100). Screening of newly-admitted horses showed that 2.2 % were carriers of MRSA. Consequent hygiene measures taken at the Clinic helped to overcome a MRSA outbreak and decrease the number of MRSA infections.

  7. Forum Engelberg 2004 to be launched in Bern on 13 November

    CERN Multimedia

    2003-01-01

    "Former French science minister Hubert Curien will be among major figures from European politics and science meeting in Bern on 13 November to launch the Forum Engelberg 2004.... Forum Engelberg provides a valuable platform for science and a forum for scientists and politicians to meet. The topic of its 2004 conference, to be held in Lucerne from 1 to 4 March 2004, is "Science on the Agenda of European Politics" (1 page).

  8. Soundscape research put into practice: The exploration of soundwalks in the city of Bern

    Directory of Open Access Journals (Sweden)

    Sweers Britta

    2017-01-01

    Full Text Available This article discusses the possibilities and broader communal impact of applied ethnomusicological work related to soundscape research in a university-based context. Focusing on a seminar in which the findings of urban soundscape research in the city of Bern (Switzerland were transformed into six different sound tours, the article analyses the different strategies and layers of impact within the broader community.

  9. Structure of rhamnose-binding lectin CSL3: unique pseudo-tetrameric architecture of a pattern recognition protein.

    Science.gov (United States)

    Shirai, Tsuyoshi; Watanabe, Yasuharu; Lee, Min-sub; Ogawa, Tomohisa; Muramoto, Koji

    2009-08-14

    The crystal structure of the L-rhamnose-binding lectin CSL3 was determined to 1.8 A resolution. This protein is a component of the germline-encoded pattern recognition proteins in innate immunity. CSL3 is a homodimer of two 20 kDa subunits with a dumbbell-like shape overall, in which the N- and C-terminal domains of different subunits form lobe structures connected with flexible linker peptides. The complex structures of the protein with specific carbohydrates demonstrated the importance of the most variable loop region among homologues for the specificity toward oligosaccharides. CSL3 and Shiga-like toxin both use Gb(3) as a cellular receptor to evoke apoptosis. They have very different overall architecture but share the separation distance between carbohydrate-binding sites. An inspection of the structure database suggested that the pseudo-tetrameric structure of CSL3 was unique among the known lectins. This architecture implies this protein might provide a unique tool for further investigations into the relationships between architecture and function of pattern recognition proteins.

  10. Molecular dynamics simulations of Gay-Berne nematic liquid crystal: Elastic properties from direct correlation functions

    International Nuclear Information System (INIS)

    Stelzer, J.; Trebin, H.R.; Longa, L.

    1994-08-01

    We report NVT and NPT molecular dynamics simulations of a Gay-Berne nematic liquid crystal using generalization of recently proposed algorithm by Toxvaerd [Phys. Rev. E47, 343, 1993]. On the basis of these simulations the Oseen-Zoher-Frank elastic constants K 11 , K 22 and K 33 as well as the surface constants K 13 and K 24 have been calculated within the framework of the direct correlation function approach of Lipkin et al. [J. Chem. Phys. 82, 472 (1985)]. The angular coefficients of the direct pair correlation function, which enter the final formulas, have been determined from the computer simulation data for the pair correlation function of the nematic by combining the Ornstein-Zernike relation and the Wienier-Hopf factorization scheme. The unoriented nematic approximation has been assumed when constructing the reference, isotropic state of Lipkin et al. By an extensive study of the model over a wide range of temperatures, densities and pressures a very detailed information has been provided about elastic behaviour of the Gay-Berne nematic. Interestingly, it is found that the results for the surface elastic constants are qualitatively different than those obtained with the help of analytical approximations for the isotropic, direct pair correlation function. For example, the values of the surface elastic constants are negative and an order of magnitude smaller than the bulk elasticity. (author). 30 refs, 9 figs

  11. Factor structure of the Bern Psychopathology Scale in a sample of patients with schizophrenia spectrum disorders.

    Science.gov (United States)

    Lang, Fabian U; Stierlin, Annabel S; Stegmayer, Katharina; Walther, Sebastian; Becker, Thomas; Jäger, Markus

    2015-10-01

    The Bern Psychopathology Scale (BPS) is based on a system-specific approach to classifying the psychopathological symptom pattern of schizophrenia. It consists of subscales for three domains (language, affect and motor behaviour) that are hypothesized to be related to specific brain circuits. The aim of the study was to examine the factor structure of the BPS in patients with schizophrenia spectrum disorders. One hundred and forty-nine inpatients with schizophrenia spectrum disorders were recruited at the Department of Psychiatry II, Ulm University, Germany (n=100) and at the University Hospital of Psychiatry, Bern, Switzerland (n=49). Psychopathology was assessed with the BPS. The VARCLUS procedure of SAS(®) (a type of oblique component analysis) was used for statistical analysis. Six clusters were identified (inhibited language, inhibited motor behaviour, inhibited affect, disinhibited affect, disinhibited language/motor behaviour, inhibited language/motor behaviour) which explained 40.13% of the total variance of the data. A binary division of attributes into an inhibited and disinhibited cluster was appropriate, although an overlap was found between the language and motor behaviour domains. There was a clear distinction between qualitative and quantitative symptoms. The results argue for the validity of the BPS in identifying subsyndromes of schizophrenia spectrum disorders according to a dimensional approach. Future research should address the longitudinal assessment of dimensional psychopathological symptoms and elucidate the underlying neurobiological processes. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  12. Die Entwicklung des Innovationsmanagements an der Universitätsbibliothek Bern

    Directory of Open Access Journals (Sweden)

    Petra Redmond

    2015-11-01

    Full Text Available Das Innovationsmanagement dient der aktiven Gestaltung von Wandlungsprozessen, welche es der Bibliothek ermöglichen, rasch auf das sich schnell verändernde Bibliotheksumfeld zu reagieren. Innovativ sein heisst folglich auch, sich ständig zu verändern. Somit sollen sich auch im Innovationsmanagement Prozesse, Strukturen und Schwerpunkte stetig wandeln können und daher sollten sie laufend evaluiert werden. Aus diesem Grund wurde zu Beginn des Innovationsmanagements an der Universitätsbibliothek Bern beschlossen, nach zwei Jahren eine erste Evaluation durchzuführen, um die Prozesse und Kernaufgaben der aktuellen Situation anpassen zu können. Die Ergebnisse zeigten, dass eine stärkere Fokussierung auf strategische Handlungsschwerpunkte und die Förderung der internen Innovationskultur notwendig sind. Als neuen Schwerpunkt setzt die UB Bern nun auf die Implementierung einer systematischen Kundenforschung. Mögliche weitere Erfolgsfaktoren für ein gelingendes Innovationsmanagement sind die enge Verknüpfung zum Projektmanagement und die Einführung eines Produktmanagements. Innovation Management is actively shaping processes which will enable libraries to respond to rapidly changing environments. Being innovative means, therefore, being able to adapt to change and disruption. Processes, structures and focuses in innovation management are also subjected to change and, as a consequence, should be constantly evaluated. For this reason, at the beginning of the implementation of innovation management at University Library Bern the decision had been taken to perform an evaluation after 2 years in order to adjust the processes and core functions to the current situation. The results highlighted that both a stronger focus on strategic priorities and the promotion of internal culture of innovation are necessary. For this purpose, UB Bern focuses on the implementation of a systematic customer research. Other possible factors for successful innovation

  13. L’affaire de Berne. Immaculée conception et apparitions de la Vierge

    Directory of Open Access Journals (Sweden)

    Sylvie Barnay

    2012-04-01

    Full Text Available En janvier 1507, les « apparitions de la Vierge » dans le couvent dominicain de Berne commencent à défrayer la chronique. L’affaire des visions de Jean Jetzer se déroule sur fond de querelle immaculiste entre dominicains et franciscains. Les dominicains du couvent de Berne ont eu l’idée de créer des apparitions de la Vierge de toutes pièces au moyen de déguisement et de machineries de théâtre pour faire croire à la conception maculée de Marie contre leurs détracteurs franciscains. Leur chef de file est le prieur du couvent, Johannes Vatter, assisté de trois autres accolytes, le sous-prieur, Franz Ueltschi, le maître en théologie et lecteur Stephan Boltzhurst, l’administrateur Heirich Steinegger. La machination qu’ils orchestrent érige de la sorte en visionnaire patenté un novice à la crédulité éprouvée, Jean Jetzer, victime de leur complot. L’affaire défie la chronique et provoque la rumeur. La ville de Berne où elle se déroule est toute proche de la Bâle du Concile (1431-1449 qui a déclaré l’Immaculée Conception « doctrine pieuse et conforme au culte de l’Église » (session du 17 septembre 1439 comme de la Bâle du Formicarius – somme démonologique de répression de la sorcellerie – composée en 1435-1437 par le prieur des dominicains, Jean Nider, sur la base des conclusions de l'inquisiteur Pierre de Berne. La « fiction » de Berne témoigne des stratégies théologiques à l’égard des révélations et des miracles dans la controverse de l’Immaculée Conception. Si elle relève ici de l’affabulation volontaire, elle montre aussi l’usage qui pouvait être fait du discours visionnaire et de son nécessaire discernement à la toute fin du Moyen Âge. L’ensemble de ce dossier exceptionnel permet dès lors de saisir l’instrumentalisation des révélations qui ont pris une importance nouvelle dans les querelles théologiques de l’Immaculée Conception à la fin du Moyen Âge.

  14. U(1) decoupling, Kleiss-Kuijf and Bern-Carrasco-Johansson relations in N=4 super Yang-Mills

    International Nuclear Information System (INIS)

    Jia Yin; Huang Rijun; Liu Changyong

    2010-01-01

    By using the Britto-Cachazo-Feng-Witten recursion relation of N=4 super Yang-Mills theory, we proved the color reflection, U(1) decoupling, Kleiss-Kuijf and Bern-Carrasco-Johansson relations for color-ordered amplitudes of N=4 super Yang-Mills theory. This proof verified the conjectured Bern-Carrasco-Johansson relations of matter fields. The proof depended only on general properties of superamplitudes. We showed also that the color reflection relation and U(1)-decoupling relation are special cases of Kleiss-Kuijf relations.

  15. The cooling facility of the Central Railway Station of Berne, Switzerland - A network operated by the city's public utilities including absorption cooling units; Kaelteverbund Bahnhof Bern, Energiecontracting mit Absorptionskaeltemaschinen

    Energy Technology Data Exchange (ETDEWEB)

    Bretscher, M.

    2004-07-01

    The energy policy of the municipality of Berne aims to create innovative technical solutions which contribute to the reduction of air pollution. This led to the idea to utilise part of the free waste heat of the city's waste incineration plant for the production of cold water. The subject of cold water production was already raised by Energie Wasser Bern in 1998. A pilot study examined the feasibility of a cold energy production unit, and consultations with land owners revealed interest in a joint solution. Project development was initiated by the Swiss Federal Railways (SBB), the Canton of Berne and the City of Berne. On the basis of the documentation produced by the engineering company KIWI AG in Duebendorf, the three constructors decided to implement central cold energy production using an absorption-type refrigerating installation in a contracting solution. The new cold energy production centre is ideally located in the basement of the SBB station main building where it was possible to integrate the existing refrigerating installation of the computer centre in the combined system. Initial operating experiences demonstrate that the incorporation of absorption-type refrigerating units in interconnected cold water systems is not quite so easy. Parallel operation of two units and precise adherence to the constant cold water temperature with a fluctuating return temperature places extreme demands on the control engineering of the installation. Approximately CHF 5.2 million have been invested in the combined cold energy installation up to autumn 2003. Energie Wasser Bern is responsible for financing, operating, maintenance and repair for a period of 20 years. The cold energy price calculated by the contractor is made up of the two components: base and operating rates. The base rate represents the fixed cost parts, i.e. the annual interest on capital and the fixed operating costs. The operating rate comprises the variable costs (mainly for primary energy

  16. EU Regulation 1143/2014 and the Bern Convention : Allied forces in the war on invasive alien species

    NARCIS (Netherlands)

    Trouwborst, Arie

    This article identifies and analyzes current and potential synergies between the new EU Regulation 1143/2014 on the prevention and management of the introduction and spread of invasive alien species on the one hand, and the Bern Convention on the Conservation of European Wildlife and Natural

  17. Methods for determination of revitalization potential of built heritage: Lessons learned on the city of Bern

    Directory of Open Access Journals (Sweden)

    Stanišić Goran

    2015-01-01

    Full Text Available Serbian conservationists could learn a lot from the revitalization example of the Old city of Bern. Analyses of this example show that the method of revitalization and protection of listed, but abandoned and inhabited, buildings depends on its future use. Alone analyses of future purpose of built heritage cannot be used as a method for its revitalization. The use of new ideas based on historical importance of the protected building generates the building's structures. The approach of revitalization through the process of building structuring and adaptation to new purpose has been tested through different analyses. It was found that the future purpose of building cannot be determined only by defining the revitalization method, set by public body, but in this process the future owner of building should actively participate. The recommendations for transferring this methodology in solving Serbian built heritage problems are given.

  18. Small hydro project in Wohlen, Bern - Preliminary study; Programm Kleinwasserkraftwerke. KWKW Hofenmuehle, Wohlen BE - Vorstudie

    Energy Technology Data Exchange (ETDEWEB)

    Fritschi, M.; Spescha, P.

    2008-11-15

    This report for the Swiss Federal Office of Energy (SFOE) presents the preliminary project study for the refurbishment of an existing small hydropower installation in Wohlen, Bern, Switzerland. The installation is in the Hofenmuehle, a listed mill complex dating from the first half of the nineteenth century. The headrace channel has already been refurbished by a community service group. The high level of financial effort and the idealism of the owner families are noted. The existing installations are described in detail. The refurbishment of the technical equipment and the associated work such as water-flow measurements are discussed. Cost estimates and environmental aspects are presented and discussed as are the financing of the refurbishment work and the cost-covering remuneration for the power produced. A possible increase in the power produced and the associated water-usage concession are discussed.

  19. Perception of Medical Students about Communication Skills Laboratory (CSL) in a Rural Medical College of Central India.

    Science.gov (United States)

    Jagzape, Tushar Bharat; Jagzape, Arunita Tushar; Vagha, Jayant Dattatray; Chalak, Anita; Meshram, Revatdhamma Jagdish

    2015-12-01

    "The art of medicine is intricately tied to the art of communication." In traditional medical curriculum, communication is not taught formally and this leads to a gap in reliability and consistency of the teaching. Few studies have shown that much litigation against doctors is due to lack of communication and not because of lack of clinical expertise. Considering the importance of training in communication skills, it was included in the curriculum of students of DMIMS (DU), which has got probably the first communication skills lab in a medical college in India. To study the perception of medical students about usefulness of communication skills lab. This observational study was carried out at Communication Skills Lab (CSL) of Jawaharlal Nehru Medical College, Sawangi (M), Wardha, Maharasthra. Feedback was obtained with the help of a prevalidated questionnaire from 65 final MBBS students about their perception about utility of the module taught in the CSL including factors which helped and which hindered in learning. Descriptive statistics was used for the quantitative data and categorization for qualitative data. A total of 78.46% students were of the idea that CSL posting is must for all medical undergraduates. A 93.83% perceive that the module taught was very relevant and useful and were satisfied with the duration of posting (81.47%). A 78.46% students experienced improvement in their communication skills. They opined that more emphasis should be given on communication between doctor and patient (61.53%). The students found communication skills lab very useful. They desired more emphasis on communication between doctor and patient and sought more interactivity, video demonstrations to be part of the module.

  20. Membrane pore architecture of the CslF6 protein controls (1-3,1-4)-β-glucan structure.

    Science.gov (United States)

    Jobling, Stephen A

    2015-06-01

    The cereal cell wall polysaccharide (1-3,1-4)-β-glucan is a linear polymer of glucose containing both β1-3 and β1-4 bonds. The structure of (1-3,1-4)-β-glucan varies between different cereals and during plant growth and development, but little is known about how this is controlled. The cellulose synthase-like CslF6 protein is an integral membrane protein and a major component of the (1-3,1-4)-β-glucan synthase. I show that a single amino acid within the predicted transmembrane pore domain of CslF6 controls (1-3,1-4)-β-glucan structure. A new mechanism for the control of the polysaccharide structure is proposed where membrane pore architecture and the translocation of the growing polysaccharide across the membrane control how the acceptor glucan is coordinated at the active site and thus the proportion of β1-3 and β1-4 bonds within the polysaccharide.

  1. Safety study of the Bio-10-SAD Bern strain of the rabies virus on the rhesus macaque monkey species

    Directory of Open Access Journals (Sweden)

    Vladimír Vrzal

    2013-01-01

    Full Text Available Based on a WHO recommendation, residual pathogenicity of the Bio-10-SAD Bern rabies virus strain (component of the Lysvulpen por. ad us. vet. vaccine was tested on rhesus macaque monkeys. Each of the ten monkeys, females, two years old, was administered orally 2 ml × 109 TCID50 of the Bio-10-SAD Bern rabies strain. The animals were monitored for 90 days. Subsequently, the animals were sacrificed and their brains were examined for presence of the vaccination rabies virus by the immunofluorescence and PCR methods. The occurrence of anti-rabies antibodies prior to and following administration of the vaccination rabies virus was also evaluated. No clinical signs of rabies were observed nor did any of the animals die of rabies following application of the virus. No rabies was detected in the study animals by post mortem examination. All of the 10 animals developed anti-rabies antibodies during the 90 days following administration of the rabies virus. It can be concluded, that Bio-10-SAD Bern virus administered at a dose equal to the tenfold maximum dose specified for field uses is safe to monkeys of the rhesus macaque species. This study is the first of its type performed in rhesus macaque monkey species.

  2. Isolated blunt severe traumatic brain injury in Bern, Switzerland, and the United States: A matched cohort study.

    Science.gov (United States)

    Haltmeier, Tobias; Schnüriger, Beat; Benjamin, Elizabeth; Brodmann Maeder, Monika; Künzler, Michael; Siboni, Stefano; Inaba, Kenji; Demetriades, Demetrios

    2016-02-01

    The ideal prehospital management of patients with severe traumatic brain injury (TBI) including the impact of endotracheal intubation (ETI) and physicians on scene is unclear. Prehospital management differs substantially in Switzerland and the United States: in Switzerland, there is usually a physician on scene who may provide ETI and other advanced life support procedures, whereas in the United States, prehospital management (including ETI) is performed by paramedics. This is a retrospective cohort-matched study of patients with isolated blunt severe TBI (head Abbreviated Injury Scale [AIS] score, 4-5) and no major extracranial injuries, using Bern University Hospital data from the Swiss PEBITA [Patient-relevant Endpoints after Brain Injury from Traumatic Accidents] (TBI-specific) database and the US National Trauma Data Bank from 2009 to 2010. A 1:4 cohort matching of Bern and US patients was performed. Matching criteria were sex, age (±10 years), exact field Glasgow Coma Scale (GCS) score, exact head AIS score, and injury type (subdural hematoma, epidural hematoma, intraparenchymal hemorrhage, intraventricular hemorrhage, brain edema/swelling, brain stem injury). The matched cohorts were compared with univariable analysis (Fisher's exact test and Mann-Whitney U-test). Matching of the Bern (n = 128) and US (n = 86,375) cohort resulted in 355 matched cases (71 Bern and 284 US patients). Bern patients had significantly longer scene times (median, 23.0 minutes vs. 9.0 minutes, p < 0.001) and more frequent prehospital ETI (31.0% vs. 18.7%, p = 0.034) and air transportation (39.4% vs. 19.4%, p < 0.001). No significant difference in procedures (craniotomy/craniectomy, intracranial pressure monitoring, tracheotomy), intensive care unit and total hospital lengths of stay, ventilator days, and in-hospital mortality (14.1% vs. 15.8%, p = 0.855) was found between the two cohorts. When taking into account the limitation that patient- and injury-related factors, but not in

  3. Effect of Corn Steep Liquor (CSL and Cassava Wastewater (CW on Chitin and Chitosan Production by Cunninghamella elegans and Their Physicochemical Characteristics and Cytotoxicity

    Directory of Open Access Journals (Sweden)

    Lúcia Raquel Ramos Berger

    2014-02-01

    Full Text Available Microbiological processes were used for chitin and chitosan production with Cunninghamella elegans UCP/WFCC 0542 grown in different concentrations of two agro-industrial wastes, corn steep liquor (CSL and cassava wastewater (CW established using a 22 full factorial design. The polysaccharides were extracted by alkali-acid treatment and characterized by infrared spectroscopy, viscosity, thermal analysis, elemental analysis, scanning electron microscopy and X-ray diffraction. The cytotoxicity of chitosan was evaluated for signs of vascular change on the chorioallantoic membrane of chicken eggs. The highest biomass (9.93 g/L was obtained in trial 3 (5% CW, 8% CSL, the greatest chitin and chitosan yields were 89.39 mg/g and 57.82 mg/g, respectively, and both were obtained in trial 2 (10% CW, 4% CSL. Chitin and chitosan showed a degree of deacetylation of 40.98% and 88.24%, and a crystalline index of 35.80% and 23.82%, respectively, and chitosan showed low molecular weight (LMW 5.2 × 103 Da. Chitin and chitosan can be considered non-irritating, due to the fact they do not promote vascular change. It was demonstrated that CSL and CW are effective renewable agroindustrial alternative substrates for the production of chitin and chitosan.

  4. Attitude towards and Readiness for Interprofessional Education in Medical and Nursing Students of Bern.

    Science.gov (United States)

    Woermann, Ulrich; Weltsch, Lena; Kunz, Alexandra; Stricker, Daniel; Guttormsen, Sissel

    2016-01-01

    Objectives: Interprofessional collaboration is becoming increasingly important in health care for various reasons. Interprofessional Education (IPE) can provide a basis for this. The aim of our study was to find out how medical (MS) and nursing students (NS) think about their own and other professions, what they know about each other, how strong their willingness to embrace IPE is, and what forms of IPE they deem useful. Methodology: Seven IPE experts rated the two measuring instruments, Readiness for Interprofessional Learning Scale RIPLS, and Interdisciplinary Education Perception Scale IEPS in terms of relevance of the items, and the quality of translation into German. Nine RIPLS items and 13 IEPS items were considered content-valid. All MS of the University of Bern and NS of the two Bernese educational institutions for nursing were invited to the online survey in the fall of 2014 by email. Results: 498 (254 MS, 244 NS) of the 2374 invited students completely filled in the questionnaire (21%). The results of the reduced RIPLS allowed no conclusive statements. When assessing their own occupational group in the IEPS, the MS attributed "competence and autonomy" to themselves significantly more frequently, while to the NS, the same was true for the item, "actual cooperation". MS know significantly less about the training of other health professionals. NS show a significantly higher willingness to embrace IPE. Teaching ethics, communication, team training, and clinical skills are deemed suitable for IPE by both groups. From the comments it appears that in both groups a majority welcomes IPE; however, the various arguments had different prevalence in both groups. Both groups fear that IPE leads to heightened stress during the study. A subgroup of MS fears a lowering of academic level. Conclusion: The results of this survey of Bernese MS and NS concerning IPE provide important information for the planning and implementation of IPE. Important steps in the introduction

  5. Trend analysis of the 20 years time series of stratospheric ozone profiles observed by the GROMOS microwave radiometer at Bern

    Science.gov (United States)

    Moreira, L.; Hocke, K.; Eckert, E.; von Clarmann, T.; Kämpfer, N.

    2015-06-01

    The ozone radiometer GROMOS (GROund-based Millimeterwave Ozone Spectrometer) performs continuous observations of stratospheric ozone profiles since 1994 above Bern, Switzerland. GROMOS is part of the Network for the Detection of Atmospheric Composition Change (NDACC). From November 1994 to October 2011, the ozone line spectra were measured by a filter bench (FB). In July 2009, a Fast-Fourier-Transform spectrometer (FFTS) has been added as backend to GROMOS. The new FFTS and the original FB measured in parallel for over two years. The ozone profiles retrieved separately from the ozone line spectra of FB and FFTS agree within 5 % at pressure levels from 30 to 0.5 hPa, from October 2009 to August 2011. A careful harmonisation of both time series has been carried out by taking the FFTS as the reference instrument for the FB. This enables us to assess the long-term trend derived from more than 20 years of stratospheric ozone observations at Bern. The trend analysis has been performed by using a robust multilinear parametric trend model which includes a linear term, the solar variability, the El Niño-Southern Oscillation (ENSO) index, the quasi-biennial oscillation (QBO), the annual and semi-annual oscillation and several harmonics with period lengths between 3 and 24 months. Over the last years, some experimental and modelling trend studies have shown that the stratospheric ozone trend is levelling off or even turning positive. With our observed ozone profiles, we are able to support this statement by reporting a statistically significant trend of +3.14 % decade-1 at 4.36 hPa, covering the period from January 1997 to January 2015, above Bern. Additionally, we have estimated a negative trend over this period of -3.94 % decade-1 at 0.2 hPa.

  6. Trend analysis of the 20-year time series of stratospheric ozone profiles observed by the GROMOS microwave radiometer at Bern

    Science.gov (United States)

    Moreira, L.; Hocke, K.; Eckert, E.; von Clarmann, T.; Kämpfer, N.

    2015-10-01

    The ozone radiometer GROMOS (GROund-based Millimeter-wave Ozone Spectrometer) has been performing continuous observations of stratospheric ozone profiles since 1994 above Bern, Switzerland (46.95° N, 7.44° E, 577 m). GROMOS is part of the Network for the Detection of Atmospheric Composition Change (NDACC). From November 1994 to October 2011, the ozone line spectra were measured by a filter bench (FB). In July 2009, a fast Fourier transform spectrometer (FFTS) was added as a back end to GROMOS. The new FFTS and the original FB measured in parallel for over 2 years. The ozone profiles retrieved separately from the ozone line spectra of FB and FFTS agree within 5 % at pressure levels from 30 to 0.5 hPa, from October 2009 to August 2011. A careful harmonisation of both time series has been carried out by taking the FFTS as the reference instrument for the FB. This enables us to assess the long-term trend derived from stratospheric ozone observations at Bern. The trend analysis was performed by using a robust multilinear parametric trend model which includes a linear term, the solar variability, the El Niño-Southern Oscillation (ENSO) index, the quasi-biennial oscillation (QBO), the annual and semi-annual oscillation and several harmonics with period lengths between 3 and 24 months. Over the last years, some experimental and modelling trend studies have shown that the stratospheric ozone trend is levelling off or even turning positive. With our observed ozone profiles, we are able to support this statement by reporting a statistically significant trend of +3.14 % decade-1 at 4.36 hPa (37.76 km), covering the period from January 1997 to January 2015, above Bern. Additionally, we have estimated a negative trend over this period of -3.94 % decade-1 at 0.2 hPa (59 km).

  7. Measurements of CO2, its stable isotopes, O2/N2, and 222Rn at Bern, Switzerland

    OpenAIRE

    Sturm, P.; Leuenberger, M.; Valentino, F. L.; Lehmann, B.; Ihly, B.

    2006-01-01

    A one-year time series of atmospheric CO2 measurements from Bern, Switzerland, is presented. O2/N2 and Ar/N2 ratios as well as stable carbon and oxygen isotopes of CO2 and δ29N2, δ34O2 and δ36Ar were measured periodically during a one year period. Additionally, the 222Rn activity was measured during three months in the winter 2004. Using the correlation from short-term fluctuations of CO2 and 222Rn we estimated a mean CO2 flux density between February...

  8. Standortbasierte Online-Informationen vermitteln: cUBe, ein Projekt der Universitätsbibliothek Bern

    Directory of Open Access Journals (Sweden)

    Reto List

    2017-12-01

    Full Text Available Die Transformation der Bibliotheksangebote schreitet immer weiter voran. In vielen Bibliotheken wird der sichtbare Buchbestand mehr und mehr von Arbeitsplätzen und Gruppenräumen verdrängt, Bibliotheken unterliegen zunehmend Neudefinitionen unter dem Label von Lern- und Begegnungsorten. Daneben nimmt die Bedeutung von elektronischen Medienangeboten und webbasierten Dienstleistungen laufend zu. Gleichzeitig ist das umfangreiche elektronische Angebot, welches Bibliotheken teuer lizensieren oder kaufen, oft nicht in aller Breite und zielgruppenbezogen bekannt und erfährt keine adäquate Nutzung. Mit dem Projekt cUBe wurde in der im Frühsommer 2016 nach umfangreicher Sanierung neu eröffneten Bibliothek Münstergasse der Universitätsbibliothek Bern der Versuch unternommen, die reichhaltigen digitalen Nachweise und Bestände für das Bibliothekspublikum sichtbarer, besser zugänglich und damit bekannter zu machen. Dabei wurde auf Basis der neuen Technologien des physischen Webs die standortbasierte Verbindung von OnlineInformationen (Katalog, E-Medien, sonstige digitale Angebote mit den entsprechenden Räumen der Bibliothek und den vor Ort noch verfügbaren Beständen realisiert. The transformation of library services is constantly proceeding. In many libraries, print collections are replaced by space designated to learning. Increasingly, our libraries are defined by labels like learning or meeting space. In addition, the importance of electronic collections and web-based services is constantly growing. However, this extensive and expensive electronic material licenced or bought by libraries is often neither known in detail and to all target groups nor used appropriately. The project cUBe was launched in late spring 2016 after an extensive renovation of the newly opened Münstergasse Library. cUBe aims at improving visibility, access and publicity of the library’s comprehensive digital references and collections for its users. On the basis of

  9. Measurements of CO2, its stable isotopes, O2/N2, and 222Rn at Bern, Switzerland

    Directory of Open Access Journals (Sweden)

    P. Sturm

    2006-01-01

    Full Text Available A one-year time series of atmospheric CO2 measurements from Bern, Switzerland, is presented. O2/N2 and Ar/N2 ratios as well as stable carbon and oxygen isotopes of CO2 and δ29N2, δ34O2 and δ36Ar were measured periodically during a one year period. Additionally, the 222Rn activity was measured during three months in the winter 2004. Using the correlation from short-term fluctuations of CO2 and 222Rn we estimated a mean CO2 flux density between February 2004 and April 2004 in the region of Bern of 95±39 tC km–2month–1. The continuous observations of carbon dioxide and associated tracers shed light on diurnal and seasonal patterns of the carbon cycle in an urban atmosphere. There is considerable variance in nighttime δ13C and δ18O of source CO2 throughout the year, however, with generally lower values in winter compared to summertime. The O2:CO2 oxidation ratio during the nighttime build-up of CO2 varies between –0.96 and –1.69 mol O2/mol CO2. Furthermore, Ar/N2 measurements showed that artifacts like thermal fractionation at the air intake are relevant for high precision measurements of atmospheric O2.

  10. [{sup 11}C]S.L.(25.1188), a new radioligand to study the monoamine oxidase type B with PET: preclinical characterisation

    Energy Technology Data Exchange (ETDEWEB)

    Saba, W.; Valette, H.; Peyronneau, M.A.; Bramoulle, Y.; Coulon, C.; Dolle, F.; Bottlaender, M. [Service Hospitalier Frederic Joliot, IIBM/DSV, 91 - Orsay (France); Curet, O.; George, P. [Sanofi-Aventis, 92 - Bagneux (France)

    2008-02-15

    Introduction. - Monoamine oxidase (M.A.O.) is a flavin containing enzyme, that catalyzes the oxidative deamination of various amines and neurotransmitters. Two isoforms exist, M.A.O.-A and M.A.O.-B. Variations in M.A.O. activity may be associated to human disease such as Parkinson and Alzheimer disease. Few radiotracers have been developed for M.A.O. PET studies such as [{sup 11}C]deprenyl, an irreversible M.A.O.-B inhibitor. Recently an oxazolidinone derivative, S.L.- 25.1188 ((S)-5-methoxy-methyl-3-[6-(4,4,4-tri-fluoro butoxy)- benzo[d]isoxazol-3-yl]-oxazolidin-2-one), belonging to a new generation of selective and reversible M.A.O.-B inhibitors was developed and showed in vitro a high selectivity for M.A.O.B. [1]. The aim of this study was to characterize [{sup 11}C]S.L.- 25.1188 as radioligand for in vivo PET examination of M.A.O.-B. Materials and methods. - PET studies of the brain distribution were carried out in male Papio anubis baboons. Selectivity and reversibility of [{sup 11}C]S.L.-25.1188 binding for M.A.O.-B was assessed by pre-treatment or displacement experiments (30 min before and after tracer injection, respectively) using reference ligands for M.A.O.-B (deprenyl: 2 mg/kg i.v. and lazabemide: 0.5 mg/kg i.v.) or by displacement experiments using unlabelled S.L.-25.1188 (1 mg/kg, i.v., 30 min after tracer injection). Distribution volume (D.V.) was calculated using 2-tissue-compartment model. The saturable binding following pre-treatment with deprenyl was considered as the specific binding. Results. - After injection, [1{sup 1C}]S.L.-25.1188 presents a rapid phase of distribution in blood (about 5 min), followed by a elimination with T1/2 of 75 min. The Blood to plasma concentration ratio was constant during the experimentation (0.9 {+-} .04) consistent with a similar kinetic of [{sup 11}C]S.L.- 25.1188 in both blood and plasma. Metabolism analysis showed that [{sup 11}C]S.L.-25.1188 is stable in vivo. In the brain, uptake in different areas was

  11. Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division

    Czech Academy of Sciences Publication Activity Database

    Převorovský, M.; Groušl, Tomáš; Staňurová, J.; Ryneš, J.; Nellen, W.; Půta, F.; Folk, P.

    2009-01-01

    Roč. 315, č. 8 (2009), s. 1533-1547 ISSN 0014-4827 R&D Projects: GA ČR(CZ) GD204/03/H066 Grant - others:UK(CZ) 157/2005/B-BIO/PrF Institutional research plan: CEZ:AV0Z50200510 Keywords : csl family * fission yeast * adhesion Subject RIV: EE - Microbiology, Virology Impact factor: 3.589, year: 2009

  12. The natural oscillations in stratospheric ozone observed by the GROMOS microwave radiometer at the NDACC station Bern

    Directory of Open Access Journals (Sweden)

    L. Moreira

    2016-08-01

    Full Text Available A multilinear parametric regression analysis was performed to assess the seasonal and interannual variations of stratospheric ozone profiles from the GROMOS (GROund-based Millimeter-wave Ozone Spectrometer microwave radiometer at Bern, Switzerland (46.95° N, 7.44° E; 577 m. GROMOS takes part in the Network for the Detection of Atmospheric Composition Change (NDACC. The study covers the stratosphere from 50 to 0.5 hPa (from 21 to 53 km and extends over the period from January 1997 to January 2015. The natural variability was fitted during the regression analysis through the annual and semi-annual oscillations (AO, SAO, the quasi-biennial oscillation (QBO, the El Niño–Southern Oscillation (ENSO and the solar activity cycle. Seasonal ozone variations mainly appear as an annual cycle in the middle and upper stratosphere and a semi-annual cycle in the upper stratosphere. Regarding the interannual variations, they are primarily present in the lower and middle stratosphere. In the lower and middle stratosphere, ozone variations are controlled predominantly by transport processes, due to the long lifetime of ozone, whereas in the upper stratosphere its lifetime is relatively short and ozone is controlled mainly by photochemistry. The present study shows agreement in the observed naturally induced ozone signatures with other studies. Further, we present an overview of the possible causes of the effects observed in stratospheric ozone due to natural oscillations at a northern midlatitude station. For instance regarding the SAO, we find that polar winter stratopause warmings contribute to the strength of this oscillation since these temperature enhancements lead to a reduction in upper stratospheric ozone. We have detected a strong peak amplitude of about 5 % for the solar cycle in lower stratospheric ozone for our 1.5 cycles of solar activity. Though the 11-year ozone oscillation above Bern is in phase with the solar cycle, we suppose

  13. The natural oscillations in stratospheric ozone observed by the GROMOS microwave radiometer at the NDACC station Bern

    Science.gov (United States)

    Moreira, Lorena; Hocke, Klemens; Navas-Guzmán, Francisco; Eckert, Ellen; von Clarmann, Thomas; Kämpfer, Niklaus

    2016-08-01

    A multilinear parametric regression analysis was performed to assess the seasonal and interannual variations of stratospheric ozone profiles from the GROMOS (GROund-based Millimeter-wave Ozone Spectrometer) microwave radiometer at Bern, Switzerland (46.95° N, 7.44° E; 577 m). GROMOS takes part in the Network for the Detection of Atmospheric Composition Change (NDACC). The study covers the stratosphere from 50 to 0.5 hPa (from 21 to 53 km) and extends over the period from January 1997 to January 2015. The natural variability was fitted during the regression analysis through the annual and semi-annual oscillations (AO, SAO), the quasi-biennial oscillation (QBO), the El Niño-Southern Oscillation (ENSO) and the solar activity cycle. Seasonal ozone variations mainly appear as an annual cycle in the middle and upper stratosphere and a semi-annual cycle in the upper stratosphere. Regarding the interannual variations, they are primarily present in the lower and middle stratosphere. In the lower and middle stratosphere, ozone variations are controlled predominantly by transport processes, due to the long lifetime of ozone, whereas in the upper stratosphere its lifetime is relatively short and ozone is controlled mainly by photochemistry. The present study shows agreement in the observed naturally induced ozone signatures with other studies. Further, we present an overview of the possible causes of the effects observed in stratospheric ozone due to natural oscillations at a northern midlatitude station. For instance regarding the SAO, we find that polar winter stratopause warmings contribute to the strength of this oscillation since these temperature enhancements lead to a reduction in upper stratospheric ozone. We have detected a strong peak amplitude of about 5 % for the solar cycle in lower stratospheric ozone for our 1.5 cycles of solar activity. Though the 11-year ozone oscillation above Bern is in phase with the solar cycle, we suppose that the strong amplitude is

  14. 2016 Consensus statement on return to sport from the First World Congress in Sports Physical Therapy, Bern

    DEFF Research Database (Denmark)

    Ardern, Clare L; Glasgow, Philip; Schneiders, Anthony

    2016-01-01

    Deciding when to return to sport after injury is complex and multifactorial-an exercise in risk management. Return to sport decisions are made every day by clinicians, athletes and coaches, ideally in a collaborative way. The purpose of this consensus statement was to present and synthesise current...... evidence to make recommendations for return to sport decision-making, clinical practice and future research directions related to returning athletes to sport. A half day meeting was held in Bern, Switzerland, after the First World Congress in Sports Physical Therapy. 17 expert clinicians participated. 4...... consensus on the content of the 4 sections. Return to sport is not a decision taken in isolation at the end of the recovery and rehabilitation process. Instead, return to sport should be viewed as a continuum, paralleled with recovery and rehabilitation. Biopsychosocial models may help the clinician make...

  15. Energetic and Entropic Contributions to the Landau–de Gennes Potential for Gay–Berne Models of Liquid Crystals

    Directory of Open Access Journals (Sweden)

    Bhaskar Gupta

    2013-03-01

    Full Text Available The Landau–de Gennes theory provides a successful macroscopic description of nematics. Cornerstone of this theory is a phenomenological expression for the effective free energy as a function of the orientational order parameter. Here, we show how such a macroscopic Landau–de Gennes free energy can systematically be constructed for a microscopic model of liquid crystals formed by interacting mesogens. For the specific example of the Gay–Berne model, we obtain an enhanced free energy that reduces to the familiar Landau–de Gennes expression in the limit of weak ordering. By carefully separating energetic and entropic contributions to the free energy, our approach reconciles the two traditional views on the isotropic–nematic transition of Maier–Saupe and Onsager, attributing the driving mechanism to attractive interactions and entropic effects, respectively.

  16. Effect of Olive Branch Aging and Extracts on the Attraction of Olive Neiroun Beetles Phloeotribus Scarabeioides (Bern

    Directory of Open Access Journals (Sweden)

    T. M. Mustafa

    1997-01-01

    Full Text Available The response of the olive neiroun beetle Phloeorribus scarabeiuides (Bern to the aging of detached olive branches at different periods of time was investigated in the laboratory using an olfactometer and in the field. Results showed that ten-day aged branches were the most attractive to the olive neiroun, indicating that semi-dried branches were more preferred than dry or fresh ones. Furthermore,  the efficiency of certain chemical solvents including n-hexane. Chloroform, acetone, methanol and distilled water in extracting the attractive substances in olive branches was studied using an olfactometer. Acetone extract was found to be the most efficient in attracting adults P. Scarabeioides. The study indicates that the olive neiroun may locate the stressed host trees or detached branches by olfactory perception of volatile compounds resulting from the stressed host tissues.

  17. The introduction of gas-powered busses in Berne; Die Einfuehrung von Gasbussen bei Bernmobil - Ein Erfahrungsbericht

    Energy Technology Data Exchange (ETDEWEB)

    Finger, D.; Kljun, N.; Keller, M.

    2008-07-01

    This report for the Swiss Federal Office of Energy (SFOE) discusses the experience gained from the operation of biogas-powered buses in Berne, Switzerland. The fleet conversion from diesel-engined buses to new vehicles powered by biogas from the city's wastewater treatment plant is discussed. Six operational aspects involved in the use of gas-powered buses in comparison with traditional diesel buses are examined and discussed. These include infrastructure adaptations, fuel and energy consumption, emissions and air-hygiene, operational changes, financial aspects and acceptance of the new vehicles both by operating personnel and the general public. Operational difficulties encountered after fire-damage to the gas filling equipment in the bus depot are noted. Fuel consumption is commented on and measurements made on emissions are discussed. The advantages and disadvantages of biogas busses in comparison with diesel busses are discussed.

  18. Quasi 18 h wave activity in ground-based observed mesospheric H2O over Bern, Switzerland

    Science.gov (United States)

    Lainer, Martin; Hocke, Klemens; Rüfenacht, Rolf; Kämpfer, Niklaus

    2017-12-01

    Observations of oscillations in the abundance of middle-atmospheric trace gases can provide insight into the dynamics of the middle atmosphere. Long-term, high-temporal-resolution and continuous measurements of dynamical tracers within the strato- and mesosphere are rare but would facilitate better understanding of the impact of atmospheric waves on the middle atmosphere. Here we report on water vapor measurements from the ground-based microwave radiometer MIAWARA (MIddle Atmospheric WAter vapor RAdiometer) located close to Bern during two winter periods of 6 months from October to March. Oscillations with periods between 6 and 30 h are analyzed in the pressure range 0.02-2 hPa. Seven out of 12 months have the highest wave amplitudes between 15 and 21 h periods in the mesosphere above 0.1 hPa. The quasi 18 h wave signature in the water vapor tracer is studied in more detail by analyzing its temporal evolution in the mesosphere up to an altitude of 75 km. Eighteen-hour oscillations in midlatitude zonal wind observations from the microwave Doppler wind radiometer WIRA (WInd RAdiometer) could be identified within the pressure range 0.1-1 hPa during an ARISE (Atmospheric dynamics Research InfraStructure in Europe)-affiliated measurement campaign at the Observatoire de Haute-Provence (355 km from Bern) in France in 2013. The origin of the observed upper-mesospheric quasi 18 h oscillations is uncertain and could not be determined with our available data sets. Possible drivers could be low-frequency inertia-gravity waves or a nonlinear wave-wave interaction between the quasi 2-day wave and the diurnal tide.

  19. Ambassadors of the Latin American and Carribean Countries accredited in Bern at ALICE experiment with Collaboration Spokesperson J. Schukraft and Non Member States Relations J. Ellis and J. Salicio Diez on 10 October 2006.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Ambassadors of the Latin American and Carribean Countries accredited in Bern at ALICE experiment with Collaboration Spokesperson J. Schukraft and Non Member States Relations J. Ellis and J. Salicio Diez on 10 October 2006.

  20. [The assessment of work-related stress in micro and small enterprises: a validation study of the instrument "CSL" (checklist on job-related stress)].

    Science.gov (United States)

    Nardella, Christian; Deitinger, Patrizia; Aiello, Antonio

    2011-01-01

    Many studies investigated the importance of a correct assessment of work-related stress because of its large effects on work planning and work management. The aim of the present study is to demonstrate the psychometric validity of the CSL Checklist questionnaire for the assessment of work related stress regarding micro and small enterprises. This tool has been conceived to investigate the perception of stress in the workplace by workers. The questionnaire has been submitted to 1033 workers belonging to 136 firms differentiated by production sectors and sizes. In order to conduct these analysis, objective data were considered too. The Principal Component Analysis (PCA) and the Confirmatory Factor Analysis (CFA), present three factors with a good internal consistency and reliability: "Organizational Culture" (alpha = .84), "Workload" (alpha = .76), and "Quality of relations and support" (alpha = .79). The Structural Equation Modelling confirms the goodness of the factorial solution (NNFI = 0,98; CFI = 0,99; RMSEA = 0,076). Good relations between the CSL dimensions and the organizational indicators have been observed (p micro and small enterprises.

  1. A 3'-coterminal nested set of independently transcribed mRNAs is generated during Berne virus replication

    International Nuclear Information System (INIS)

    Snijder, E.J.; Horzinek, M.C.; Spaan, W.J.

    1990-01-01

    By using poly(A)-selected RNA from Berne virus (BEV)-infected embryonic mule skin cells as a template, cDNA was prepared and cloned in plasmid pUC9. Recombinants covering a contiguous sequence of about 10 kilobases were identified. Northern (RNA) blot hybridizations with various restriction fragments from these clones showed that the five BEV mRNAs formed a 3'-coterminal nested set. Sequence analysis revealed the presence of four complete open reading frames of 4743, 699, 426, and 480 nucleotides, with initiation codons coinciding with the 5' ends of BEV RNAs 2 through 5, respectively. By using primer extension analysis and oligonucleotide hybridizations, RNA 5 was found to be contiguous on the consensus sequence. The transcription of BEV mRNAs was studied by means of UV mapping. BEV RNAs 1, 2, and 3 were shown to be transcribed independently, which is also likely--although not rigorously proven--for RNAs 4 and 5. Upstream of the AUG codon of each open reading frame a conserved sequence pattern was observed which is postulated to function as a core promoter sequence in subgenomic RNA transcription. In the area surrounding the core promoter region of the two most abundant subgenomic BEV RNAs, a number of homologous sequence motifs were identified

  2. Probabilistic Estimates of Global Marine N2O Emissions within the Bern3D Earth System Model of Intermediate Complexity

    Science.gov (United States)

    Keller, K. M.; Battaglia, G.; Joos, F.

    2016-02-01

    Nitrous oxide (N2O) is a radiatively active atmospheric trace gas (currently 325 ppb, increasing by 0.25% yr-1) and is emitted to the atmosphere from poorly constrained microbial processes on land and in the oceans. The latest estimates given by the IPCC for marine N2O sources range from 1.8-9.4 TgN yr-1. Marine N2O production is commonly parameterized as a function of organic matter remineralization, oxygen concentrations, or temperature to account for (chemo-autotrophic) nitrification and (chemo-heterotrophic) denitrification processes. We implemented different production schemes in the cost-efficient Bern3D Earth-System Model of Intermediate Complexity which features a 3-D frictional-geostrophic ocean and an OCMIP2-type marine carbon cycle. We optimize the parameters governing N2O production in a probabilistic, Monte-Carlo-type, Bayesian framework by applying observed dissolved N2O data, compiled in the MEMENTO database, as constraints. N2O emissions of the observation-constrained model ensemble will then be determined for both future and past (e.g. Younger-Dryas) environmental conditions.

  3. When is it acceptable to kill a strictly protected carnivore? Exploring the legal constraints on wildlife management within Europe’s Bern Convention

    Directory of Open Access Journals (Sweden)

    John D. C. Linnell

    2017-09-01

    Full Text Available As wolf populations expand across Europe, many countries face challenges in finding ways to address the concerns of some elements among the rural stakeholders who are being asked to share their landscapes with wolves for the first time in several generations. In these recovery landscapes, wolves are associated with a wide range of conflicts that include economic, psychological, perceptional, social, cultural and political dimensions. A recurring demand concerns the desire to introduce the use of carefully regulated lethal control of wolves, through either culling by state employees or hunting conducted by rural hunters. Introducing such measures can be very controversial, and many critics challenge their legality under the international wildlife conservation instruments that have nurtured wolf recovery. We evaluate this issue for the case of wolves in Norway, which are strictly protected under the Bern Convention. Drawing on the latest results of social science research, we present the multiple lines of argumentation that are often used to justify killing wolves and relate these to the criteria for exceptions that exist under the Bern Convention. We conclude that while the Convention provides apparent scope for allowing the killing of wolves as a means to address conflicts, this must be clearly justified and proportional to the conservation status of wolves so as to not endanger their recovery.

  4. Modelling and mapping of spatial differentiated impacts of nitrogen input to ecosystems within the framework of the UNECE-Convention of Air Pollution Prevention. Part II. The model BERN - assessment of vegetation change and biodiversity; Modellierung und Kartierung raeumlich differenzierter Wirkungen von Stickstoffeintraegen in Oekosysteme im Rahmen der UNECE-Luftreinhaltekonvention. Teilbericht II. Das BERN-Modell - ein Bewertungsmodell fuer die oberirdische Biodiversitaet

    Energy Technology Data Exchange (ETDEWEB)

    Nagel, Hans-Dieter; Schlutow, Angela; Kraft, Philipp; Scheuschner, Thomas; Weigelt-Kirchner, Regine [OEKO-DATA - Ecosystem Analysis and Environmental Data Management, Strausberg (Germany)

    2010-03-15

    Semi-natural ecosystems are exposed to high atmospheric deposition for decades. In contrary to sulphur deposition which could be significantly reduced due to international conventions on air pollution prevention during the last decades, deposition of both, reduced and oxidized nitrogen is still on a very high level in average 40 kg N ha{sup -1} yr{sup -1} in forest ecosystems in Germany. The FuE-Project ''Modelling and mapping of spatial differentiated impacts of nitrogen input to ecosystems within the framework of the UNECE - Convention of Air Pollution Prevention'' was jointly conducted by 4 partner institutions and studied impacts of atmospheric nitrogen deposition and climate change on physicochemical properties of forest soils, nutrient storage and nutrient export (Karlsruhe Research Centre, IMK-IFU) as well as biodiversity of vegetation (OEKO-DATA and Waldkundeinstitut Eberswalde) and soil organisms (Giessen University). Work carried out at OEKO-DATA initially concentrated on the development of the BERN-model. About 14 585 vegetation inventories from all over Germany and other 2 914 relevant inventories evaluated from neighboring countries were integrated in BERN database. With this model, the vegetation changes as a function of variations in the location conditions could be identified due to the implementation of the corresponding time series of geochemical and climate parameters from MoBiLE. A validation of the MoBiLE-BERN-coupling was carried out at Level II sites. From the dynamics of the vegetation development in the context of location changes could be derived critical loads and limits. Also the current regeneration potential as well as a harmonious natural balance of location factors could be determined. Likewise, the potential of danger to biodiversity and the livelihood opportunities of plant species or societies could be demonstrated. The most distinct dependence of biodiversity change could be detected on the alterations of

  5. Professor Darleane C. Hoffman, Senior Advisor & Charter Director Seaborg Institute for Transactinium Science Livermore, California and Dr Marvin Hoffman accompanied by Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institut Villigen.

    CERN Multimedia

    Maximilien Brice

    2001-01-01

    Photo 02 : Visit of Professor Darleane C. Hoffman, Senior Advisor & Charter Director, Seaborg Institute for Transactinium Science, Livermore, California with (from left to right) Dr Mats Lindroos, ISOLDE Technical Coordinator; Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institute Villigen, and Dr Marvin Hoffman.

  6. [A million football fans in a city of 120,000 inhabitants--a nightmare for emergency medicine and disaster management? Euro 2008 and the "Orange wonder of Berne"].

    Science.gov (United States)

    Martinolli, L; Tanyeli, E; Hasler, R M; Burkhardt, P; Bähler, H; Neff, F; Rupp, P; Zimmermann, H; Exadaktylos, A K

    2011-01-01

    The 2008 European Football Championship 2008 (Euro 08) is the largest sporting event ever organized in Switzerland. One million visitors came to the city of Berne during the event and the local airport in Bern/Belp registered 261 extra flights. For each football game there were 33,000 fans in the stadium and 100,000 fans in the public viewing zones.The ambulance corps and the Department of Emergency Medicine (ED) at Inselspital, University Hospital Berne, were responsible for basic medical care and emergency medical management. Injuries and illnesses were analyzed by a standardized score (NACA score). The preparation strategy as well as costs and patient numbers are presented in detail.A total of 30 additional ambulance vehicles were used, 4,723 additional working days (one-third medical professionals) were accumulated, 662 ambulance calls were registered and 240 persons needed medical care (62% Swiss, 28% Dutch and 10% other nationalities). Among those needing treatment 51 were treated in 1 of the 4 city hospitals. No injuries with NACA grades VI and VII occurred (NACA I: 4, NACA II: 17, NACA III: 16, NACA IV: 10 and NACA V: 4 patients). The city of Berne compensated the Inselspital Bern with a total of 112,603 Euros for extra medical care costs. The largest amount was spent on security measures (50,300 Euros) and medical staff (medical doctors 22,600 Euros, nurses 29,000 Euros). Because of the poor weather and the exemplary behavior of the fans, the course of events was rather peaceful.

  7. 20th century changes in carbon isotopes and water-use efficiency: tree-ring-based evaluation of the CLM4.5 and LPX-Bern models

    Science.gov (United States)

    Keller, Kathrin M.; Lienert, Sebastian; Bozbiyik, Anil; Stocker, Thomas F.; Churakova (Sidorova), Olga V.; Frank, David C.; Klesse, Stefan; Koven, Charles D.; Leuenberger, Markus; Riley, William J.; Saurer, Matthias; Siegwolf, Rolf; Weigt, Rosemarie B.; Joos, Fortunat

    2017-05-01

    Measurements of the stable carbon isotope ratio (δ13C) on annual tree rings offer new opportunities to evaluate mechanisms of variations in photosynthesis and stomatal conductance under changing CO2 and climate conditions, especially in conjunction with process-based biogeochemical model simulations. The isotopic discrimination is indicative of the ratio between the CO2 partial pressure in the intercellular cavities and the atmosphere (ci/ca) and of the ratio of assimilation to stomatal conductance, termed intrinsic water-use efficiency (iWUE). We performed isotope-enabled simulations over the industrial period with the land biosphere module (CLM4.5) of the Community Earth System Model and the Land Surface Processes and Exchanges (LPX-Bern) dynamic global vegetation model. Results for C3 tree species show good agreement with a global compilation of δ13C measurements on leaves, though modeled 13C discrimination by C3 trees is smaller in arid regions than measured. A compilation of 76 tree-ring records, mainly from Europe, boreal Asia, and western North America, suggests on average small 20th century changes in isotopic discrimination and in ci/ca and an increase in iWUE of about 27 % since 1900. LPX-Bern results match these century-scale reconstructions, supporting the idea that the physiology of stomata has evolved to optimize trade-offs between carbon gain by assimilation and water loss by transpiration. In contrast, CLM4.5 simulates an increase in discrimination and in turn a change in iWUE that is almost twice as large as that revealed by the tree-ring data. Factorial simulations show that these changes are mainly in response to rising atmospheric CO2. The results suggest that the downregulation of ci/ca and of photosynthesis by nitrogen limitation is possibly too strong in the standard setup of CLM4.5 or that there may be problems associated with the implementation of conductance, assimilation, and related adjustment processes on long-term environmental

  8. District Heating using a gas-motor-driven heat pump - result checking; Erfolgskontrolle. Heizzentrale mit indirekter Gasmotor-Waermepumpe. Berufsschulen Bern-Lorraine

    Energy Technology Data Exchange (ETDEWEB)

    Eggen, B.; Lanz, S.

    2003-07-01

    This final report for the Swiss Federal Office of Energy presents the results of a project that evaluated the operation of a district heating scheme that supplies various school and college buildings, residential buildings and Berne's Botanical Gardens with heat. This pilot and demonstration system comprises an indirect gas motor heat pump with co-generation unit and an electrically-driven heat pump. In order to achieve a high performance ratio the co-generation unit was additionally equipped with a heat-recovery heat pump which condenses the waste gas and recovers radiation heat losses. The implementation of the district heating project was done in stages to meet annual heat demands of around 6'500 MWh. About 50% of these demands are met by the indirect gas motor heat pump. Figures are presented on the optimisation of heat utilisation from ground water which permitted an improvement in the total efficiency of the plant of around 30% compared with a conventional installation. The authors state that, with this installation, it could be demonstrated in an exemplary fashion that heat pumps can also be installed in existing, non-renovated buildings. In the planning of such heat pump systems they recommend that special attention be paid to the overall performance ratio, and that the rate of flow of the heat source and system temperatures be taken into account.

  9. BERNE-COPENHAGUE-MADRID-PARÍS-SANTIAGO: INTERPOLACIONES RELATIVISTAS, VARIACIONES CUÁNTICAS E IMPACTOS CÓSMICOS EN ALTAZOR (1919-1931

    Directory of Open Access Journals (Sweden)

    Scott Weintraub

    2010-04-01

    Full Text Available En este artículo para el número especial de Revista Chilena de Literatura que conmemora el bicentenario chileno, exploro múltiples conexiones literarias, científicas, y geográficas entre el poema Altazor de Vicente Huidobro y los contextos filosófico-científicos globales de las primeras décadas del siglo XX. Evalúo el impacto de una serie de caídas lingüísticas, críticas, alegóricas y gravitacionales en la trayectoria del "viaje en paracaídas" de Altazor, para volver a considerar, desde varias perspectivas críticas que tratan la "ilegible" y ambigua conclusión del poema, el impacto de un evento lingüístico en el campo de gravedad del poema. De esta manera, el artículo examina el imaginario científico que Altazor comparte con ciertos descubrimientos clave en la física teórica y experimental durante la primera parte del siglo XX, vinculando la escena poética vanguardista chilena y europea (Madrid-Paris-Santiago con los avances científicos de la época (Berne-Copenhague. Dicha indagación histórico-contextual con el cambio de paradigma involucrado en el universo cuántico-relativista -contemporáneo a la fecha de composición del poema- exige una exploración de las maneras en que Altazor qua texto poético marca el paso discursivo entre las cosmovisiones newtonianas y cuánticas. El campo semántico de Altazor, examinado con respecto a estas cuestiones cosmológicas, demuestra cómo el poema largo de Huidobro marca un evento lingüístico y cósmico que, no obstante, es sin horizonte de expectativa y así radicalmente heterogéneo en su naturaleza -faceta del poema que subraya el tipo de variaciones y flujos cuánticos cuyos "senderos" no se pueden predecir con certidumbre.In this article for the special issue of Revista Chilena de Literatura devoted to Chile 's bicentennial, I explore multiple literary, scientific, and geographic connections between Vicente Huidobro s poem Altazor and the global philosophical

  10. GPU-Accelerated Molecular Dynamics Simulation to Study Liquid Crystal Phase Transition Using Coarse-Grained Gay-Berne Anisotropic Potential.

    Science.gov (United States)

    Chen, Wenduo; Zhu, Youliang; Cui, Fengchao; Liu, Lunyang; Sun, Zhaoyan; Chen, Jizhong; Li, Yunqi

    2016-01-01

    Gay-Berne (GB) potential is regarded as an accurate model in the simulation of anisotropic particles, especially for liquid crystal (LC) mesogens. However, its computational complexity leads to an extremely time-consuming process for large systems. Here, we developed a GPU-accelerated molecular dynamics (MD) simulation with coarse-grained GB potential implemented in GALAMOST package to investigate the LC phase transitions for mesogens in small molecules, main-chain or side-chain polymers. For identical mesogens in three different molecules, on cooling from fully isotropic melts, the small molecules form a single-domain smectic-B phase, while the main-chain LC polymers prefer a single-domain nematic phase as a result of connective restraints in neighboring mesogens. The phase transition of side-chain LC polymers undergoes a two-step process: nucleation of nematic islands and formation of multi-domain nematic texture. The particular behavior originates in the fact that the rotational orientation of the mesogenes is hindered by the polymer backbones. Both the global distribution and the local orientation of mesogens are critical for the phase transition of anisotropic particles. Furthermore, compared with the MD simulation in LAMMPS, our GPU-accelerated code is about 4 times faster than the GPU version of LAMMPS and at least 200 times faster than the CPU version of LAMMPS. This study clearly shows that GPU-accelerated MD simulation with GB potential in GALAMOST can efficiently handle systems with anisotropic particles and interactions, and accurately explore phase differences originated from molecular structures.

  11. ¿Qué hacer con el ángel? J. L. Borges y F. L. Bernárdez, dos formas de escribir la experiencia mística

    Directory of Open Access Journals (Sweden)

    Lucas Adur

    2015-06-01

    Full Text Available Este trabajo propone una lectura de dos textos de escritores argentinos, publicados casi contemporáneamente, El buque (1935 de Francisco Luis Bernárdez y “El acercamiento a Almotásim” (1936 de Jorge Luis Borges, que pueden considerarse como dos modos, diametralmente opuestos, de dar cuenta de una experiencia mística. Una “positiva”, que apuesta por un discurso conceptual y una “negativa” que opta por la alusión, la paradoja y el silencio. El poema de Bernárdez tiene en su centro una revelación mística, experimentada por el yo lírico, que es transmisible en términos discursivos y que implica una propuesta moral. En este sentido, puede pensarse que El buque es representativo de la estética sostenida por un grupo de poetas católicos que, apoyados en la teología escolástica, proponían que la literatura debía estar al servicio de la difusión del mensaje cristiano y del renacimiento espiritual del pueblo. Borges escribe una reseña de este poema y, meses después, “El acercamiento a Almotásim”, relato que puede leerse como una respuesta polémica a la forma de presentar la experiencia mística que propone el texto de Bernárdez. Frente al “decir excesivo” que atribuye al poeta católico, Borges subraya en su escritura la dimensión inefable, intransmisible que caracteriza para él a toda experiencia directa de lo trascendente.

  12. Measurements of CO2, its stable isotopes, O2/N2, and 222Rn at Bern, Switzerland

    OpenAIRE

    Sturm, P.; Leuenberger, M.; Valentino, F. L.; Lehmann, B.; Ihly, B.

    2006-01-01

    A one-year time series of atmospheric CO2 measurements from Bern, Switzerland, is presented. O2/N2 and Ar/N2 ratios as well as stable carbon and oxygen isotopes of CO2 and δ29N2, δ34O2 and δ36Ar were measured periodically during a one year period. Additionally, the 222Rn activity was measured during three months in the winter 2004. Using the correlation from short-term fluctuations of CO2 and 222Rn we estimated a mean CO2 flux density between February 2004 and April 2004 in ...

  13. Rationale and design of Apo-I Event Reduction in Ischemic Syndromes I (AEGIS-I): A phase 2b, randomized, placebo-controlled, dose-ranging trial to investigate the safety and tolerability of CSL112, a reconstituted, infusible, human apoA-I, after acute myocardial infarction.

    Science.gov (United States)

    Gibson, C Michael; Korjian, Serge; Tricoci, Pierluigi; Daaboul, Yazan; Alexander, John H; Steg, Philippe G; Lincoff, A Michael; Kastelein, John J P; Mehran, Roxana; D'Andrea, Denise; Merkely, Bela; Zarebinski, Maciej; Ophius, Ton Oude; Harrington, Robert A

    2016-10-01

    Despite aggressive pharmacotherapy and stenting, there is a residual risk of major adverse cardiovascular events among patients with acute coronary syndrome. High-density lipoprotein (HDL) has been a major target for secondary acute coronary syndrome prevention; however, a better understanding of the physiologic function of HDL has demonstrated that a high cholesterol efflux capacity, rather than high HDL concentrations alone, may be critical to improving outcomes. CSL112, a reconstituted, infusible human apolipoprotein A-I, has been demonstrated to increase cholesterol efflux capacity and to have a protective effect in experimental models of atherosclerotic cardiovascular disease. The AEGIS-I trial (ClinicalTrials.govNCT02108262) is a phase 2b, multicenter, randomized, placebo-controlled, dose-ranging clinical trial to evaluate the hepatic and renal safety of multiple administrations of 2 doses of CSL112 among subjects with acute myocardial infarction (AMI). Approximately 1,200 subjects (400 per treatment group) with either normal renal function or mild renal impairment will be enrolled up to 7 days after an AMI and will be stratified by renal function and randomized in a 1:1:1 ratio to either 1 of 2 doses of CSL112 (either 2 g or 6 g) or placebo as a weekly 2-hour infusion over the course of 4 consecutive weeks. The coprimary safety endpoints will be the incidence of hepatic and renal toxicity, defined as either confirmed ALT >3 × ULN, total bilirubin >2 × ULN, serum creatinine ≥1.5×baseline value, or a new requirement for renal replacement therapy through the end of the active treatment period. The AEGIS-I trial will characterize the safety profile of CSL112, a reconstituted formulation of apolipoprotein A-I, and will assess if administration to patients with a recent AMI is associated with a clinically significant alteration in either liver or kidney function when compared with placebo. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Kaposi's sarcoma-associated herpesvirus Rta tetramers make high-affinity interactions with repetitive DNA elements in the Mta promoter to stimulate DNA binding of RBP-Jk/CSL.

    Science.gov (United States)

    Palmeri, Diana; Carroll, Kyla Driscoll; Gonzalez-Lopez, Olga; Lukac, David M

    2011-11-01

    Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 [HHV-8]) is the etiologic agent of Kaposi's sarcoma (KS) and lymphoproliferative diseases. We previously demonstrated that the KSHV lytic switch protein Rta stimulates DNA binding of the cellular RBP-Jk/CSL protein, the nuclear component of the Notch pathway, on Rta target promoters. In the current study, we define the promoter requirements for formation of transcriptionally productive Rta/RBP-Jk/DNA complexes. We show that highly pure Rta footprints 7 copies of a previously undescribed repetitive element in the promoter of the essential KSHV Mta gene. We have termed this element the "CANT repeat." CANT repeats are found on both strands of DNA and have a consensus sequence of ANTGTAACANT(A/T)(A/T)T. We demonstrate that Rta tetramers make high-affinity interactions (i.e., nM) with 64 bp of the Mta promoter but not single CANT units. The number of CANT repeats, their presence in palindromes, and their positions relative to the RBP-Jk binding site determine the optimal target for Rta stimulation of RBP-Jk DNA binding and formation of ternary Rta/RBP-Jk/DNA complexes. DNA binding and tetramerization mutants of Rta fail to stimulate RBP-Jk DNA binding. Our chromatin immunoprecipitation assays show that RBP-Jk DNA binding is broadly, but selectively, stimulated across the entire KSHV genome during reactivation. We propose a model in which tetramerization of Rta allows it to straddle RBP-Jk and contact repeat units on both sides of RBP-Jk. Our study integrates high-affinity Rta DNA binding with the requirement for a cellular transcription factor in Rta transactivation.

  15. Kaposi's Sarcoma-Associated Herpesvirus Rta Tetramers Make High-Affinity Interactions with Repetitive DNA Elements in the Mta Promoter To Stimulate DNA Binding of RBP-Jk/CSL ▿ †

    Science.gov (United States)

    Palmeri, Diana; Carroll, Kyla Driscoll; Gonzalez-Lopez, Olga; Lukac, David M.

    2011-01-01

    Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 [HHV-8]) is the etiologic agent of Kaposi's sarcoma (KS) and lymphoproliferative diseases. We previously demonstrated that the KSHV lytic switch protein Rta stimulates DNA binding of the cellular RBP-Jk/CSL protein, the nuclear component of the Notch pathway, on Rta target promoters. In the current study, we define the promoter requirements for formation of transcriptionally productive Rta/RBP-Jk/DNA complexes. We show that highly pure Rta footprints 7 copies of a previously undescribed repetitive element in the promoter of the essential KSHV Mta gene. We have termed this element the “CANT repeat.” CANT repeats are found on both strands of DNA and have a consensus sequence of ANTGTAACANT(A/T)(A/T)T. We demonstrate that Rta tetramers make high-affinity interactions (i.e., nM) with 64 bp of the Mta promoter but not single CANT units. The number of CANT repeats, their presence in palindromes, and their positions relative to the RBP-Jk binding site determine the optimal target for Rta stimulation of RBP-Jk DNA binding and formation of ternary Rta/RBP-Jk/DNA complexes. DNA binding and tetramerization mutants of Rta fail to stimulate RBP-Jk DNA binding. Our chromatin immunoprecipitation assays show that RBP-Jk DNA binding is broadly, but selectively, stimulated across the entire KSHV genome during reactivation. We propose a model in which tetramerization of Rta allows it to straddle RBP-Jk and contact repeat units on both sides of RBP-Jk. Our study integrates high-affinity Rta DNA binding with the requirement for a cellular transcription factor in Rta transactivation. PMID:21880753

  16. MASCOT: a new mass-spectrometer facility dedicated to the analysis of cosmogenic noble gases (3He and 21Ne) from terrestrial samples (Institute of Geological Sciences - University of Bern, Switzerland).

    Science.gov (United States)

    Delunel, Romain; Enderli, Patrick; Jenni, Hans-Erich; Leya, Ingo; Schlunegger, Fritz

    2017-04-01

    In the past years, terrestrial cosmogenic nuclides have been successfully used for dating exposure history of landforms and measuring erosional processes on Earth's surface. In this context, quantifications of landscape change have mainly been accomplished through the use of radioactive cosmogenic nuclides such as 10Be and 26Al, but their application has generally been restricted to Quaternary time scales because of their relatively short half-lives. The results are 10Be and 26Al concentrations that are below the detection limit of available accelerator mass spectrometers if the samples have a Late Miocene or even a Pliocene age. Contrariwise, cosmogenic noble gases such as 3He and 21Ne do not experience any radioactive decay through time, which places these isotopes in an unbeatable position for measuring paleo-denudation rates preserved in detrital material even if the ages of these deposits are up to 10 Ma and even older. These isotopes are thus keys for assessing the interplays between tectonic, climate and surface processes involved in the long-term evolution of mountain belts. Here we report the technical specifications of a noble gas analytical system that we have developed and set up at the Institute of Geological Sciences of the University of Bern, Switzerland, with the motivations to get dates and rates of erosion processes from the measurement of cosmogenic noble gases (3He and 21Ne) concentrations from terrestrial samples. This new facility, hosted at the Institute of Geological Sciences of the University of Bern, combines a MAP215-50 mass spectrometer fitted with a new high-sensitivity channel electron multiplier with an all-metal extraction and purification line. This later system thus comprises: (i) a double vacuum resistance furnace loaded by a 22-samples carrousel, (ii) three in-vacuo crushers (iii) an ultra high vacuum pumping system (ion-getter pumps and backed by a scroll pump, (iv) the line itself made up of a series of valves, connectors, a

  17. The Marquis de Condorcet goes to Bern

    DEFF Research Database (Denmark)

    Bochsler, Daniel

    2010-01-01

    JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about...

  18. The Bern Infinitesimal Bubble Chamber (BIBC)

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    The chamber body was machined from a block of aluminium. The visible volume was cylindrical with 65 mm diameter and 35 mm depth. It was filled with propane or freon. It was meant as vertex detector in the search of short-lived particles. It was also used with in-line holography resulting in 8 µm bubble size and 9 cm depth of the field. See E. Ramseyer, B. Hahn and E. Hugentobler, Nucl. Instrum. Methods 201 (1982) 335.

  19. Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial.

    Science.gov (United States)

    van Schaik, Ivo N; Bril, Vera; van Geloven, Nan; Hartung, Hans-Peter; Lewis, Richard A; Sobue, Gen; Lawo, John-Philip; Praus, Michaela; Mielke, Orell; Durn, Billie L; Cornblath, David R; Merkies, Ingemar S J

    2018-01-01

    ). Causally related adverse events occurred in 47 (27%) patients (ten [18%] in the placebo group, 17 [30%] in the low-dose group, and 20 [34%] in the high-dose group). Six (3%) patients had 11 serious adverse events: one (2%) patient in the placebo group, three (5%) in the low-dose group, and two (3%) in the high-dose group; only one (an acute allergic skin reaction in the low-dose group) was assessed to be causally related. This study, which is to our knowledge, the largest trial of CIDP to date and the first to study two administrations of immunoglobulins and two doses, showed that both doses of SCIg IgPro20 were efficacious and well tolerated, suggesting that SCIg can be used as a maintenance treatment for CIDP. CSL Behring. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Center on Survivability and Lethality (CSL) Research Faculty

    OpenAIRE

    2013-01-01

    NPS has a strong history in teaching and research in aircraft survivability and air defense lethality. On Jan. 30, the Naval Postgraduate School (NPS) announced the creation of the Center for Survivability and Lethality. The new center builds upon the pioneering work of Distinguished Professor Emeritus Robert Ball, who founded the first and only course on all aspects of aircraft combat survivability at NPS in the 1970s and wrote the field’s ‘bible,’ The Fundamentals of Aircraft Comba...

  1. Right Hemisphere and Left Hemisphere: Pedagogical Implications for CSL Reading.

    Science.gov (United States)

    Mickel, Stanley L.

    Students can be taught to read Chinese more efficiently and accurately by using the specific capabilities of the right and left hemispheres of the brain. The right hemisphere is the site of image and pattern recognition, and students can be taught to use those capacities to process individual characters efficiently by watching for the element of…

  2. Model checking conditional CSL for continuous-time Markov chains

    DEFF Research Database (Denmark)

    Gao, Yang; Xu, Ming; Zhan, Naijun

    2013-01-01

    In this paper, we consider the model-checking problem of continuous-time Markov chains (CTMCs) with respect to conditional logic. To the end, we extend Continuous Stochastic Logic introduced in Aziz et al. (2000) [1] to Conditional Continuous Stochastic Logic (CCSL) by introducing a conditional p...

  3. Loss functions for structural flood mitigation measures | Berning ...

    African Journals Online (AJOL)

    The paper aims at discussing the methodology used to develop loss functions for flood mitigation measures, using historic data of flood damage to infrastructure. The main determinants of the extent of damage are the size of the flood and the length of the infrastructure within the boundaries of the flood-line. In regression ...

  4. Urban hybrid : Bern-Ausserhollingen, Sveits / Inga Raukas, Toomas Tammis

    Index Scriptorium Estoniae

    Raukas, Inga, 1967-

    1999-01-01

    Arhitektuuriagentuuri (Inga Raukas, Toomas Tammis, Tarmo Teedumäe, Eero Endjärv) tööst noorte arhitektide konkursil Europan 5 "Uued elamismaastikud, liikumine ja lähedus". 26.-29. IX 1999 Genfis toimunud rahvusvahelisest foorumist, millel Eestist osalesid Tõnu Laigu ja Inga Raukas. 5 ill

  5. LRN, ERN:, & BERN @ Wireless Integrating the Sciences (WITS) Theatre

    Science.gov (United States)

    Hilliard, L.; Campbell, B.; Foody, M.; Klitsner, D.

    2010-01-01

    In order to develop a call to action for a learning tool that would work to best teach Science Technology Engineering and Math (STEM), the NASA Goddard team will partner with the inventor of Bop It!, an interactive game of verbs and following instructions; and Global Imagination, the developers of Magic Planet. In this paper Decision-making Orbital Health! (DOH!) will be described as a game derived from the basic functions necessary for Bop lt!, a familiar game. that will ask the educational audience to respond to changing commands to Bop It!, Twist It!, and Squeeze It! The success of the new version of the game, will be that the Earth will be making these commands from Dynamic Planet, and the crowd assembled can play wirelessly. Wireless Integrating The Sciences (WITS) Theatre : A balanced approach will describe how the communities local to Goddard and perhaps San Francisco will develop curriculum that helps kids teach kids with an engaging game and a STEM message. The performing arts will be employed to make it entertaining and appropriate to the size of the gathering, and the students educational level.

  6. Food Security (CSL Issue Paper, Volume 14-09, September 2009)

    Science.gov (United States)

    2009-09-01

    since 2007 erratic rainfall in southern Africa has exacerbated the regional food shortage problem as droughts destroyed maize crops (a staple of the...and improving responses to food emergency crises.” 31 The AU also recommended, “Member states and RECs promote and protect rice, legumes, maize ...cotton, oil palm, beef, dairy, poultry and fisheries products as strategic commodities at the continental level.”32 Sustainability of these cash

  7. A computer simulation of a potential derived from the gay-berne ...

    African Journals Online (AJOL)

    The results are compared against predictions of molecular field theory, experimental results and that of other related simulations wherever possible. It is shown that for more elongated molecules the nematic-isotropic transition becomes stronger first order transition. For a given molecular elongation as the intermolecular ...

  8. 75 FR 37720 - Safety Zone; New Bern Air Show, Neuse River, NC

    Science.gov (United States)

    2010-06-30

    ... Carolina. In recent years, there have been unfortunate instances of aircraft crashes during performances at air shows. Typical of plane crashes, there is a wide area of scattered debris that damages property...; test methods; sampling procedures; and related management systems practices) that are developed or...

  9. Part[h]enope. Naples et les arts / Napoli e le arti, Bern, Peter Lang ...

    African Journals Online (AJOL)

    User

    Ripensare la cultura sviluppatasi nelle grandi città del Mediterraneo in termini storici, ma senza tacere i colpi di scena ... quel «creuset de contradictions multiculturelles» (per usare l'espressione di Faverzani) che Napoli è .... in Italia, e uno del nostro Mario. Martone, Teatro di guerra (1998): la Napoli barocca, tra la tirannica ...

  10. Communication Sciences Laboratory Quarterly Progress Report, Volume 9, Number 3: Research Programs of Some of the Newer Members of CSL.

    Science.gov (United States)

    Feinstein, Stephen H.; And Others

    The research reported in these papers covers a variety of communication problems. The first paper covers research on sound navigation by the blind and involves echo perception research and relevant aspects of underwater sound localization. The second paper describes a research program in acoustic phonetics and concerns such related issues as…

  11. CSL Issue Paper. March 2008, Volume 3-08. New Media and the Warfighter. Workshop Initial Impressions

    National Research Council Canada - National Science Library

    Murphy, Dennis

    2008-01-01

    .... Anyone armed with mobile technologies such as a camera cell phone and access to the internet is capable of affecting strategic outcomes at very low cost, using a minimal information infrastructure. The U.S...

  12. China’s Pursuit of Africa’s Natural Resources, (CSL Issue Paper, Volume 1-09, June 2009)

    Science.gov (United States)

    2009-06-01

    was $1.25 billion, and some sources, such as The People’s Daily, believe that it exceeded $6 billion in 2007 (Amosu, 2007; Broadman , 2008). Trade with... Broadman , Harry G. 2008. “New Trade Directions for Africa on Asia’s Silk Road.” The World Bank. http://web.worldbank.org/ WBSITE/EXTERNAL/COUNTRIES

  13. The International Conference of Military Engineers and the Environment (CSL Issue Paper, Volume 4-10, July 2010)

    Science.gov (United States)

    2010-07-01

    previous speakers addressed diverse topics such as the efforts to mitigate the effects of an off-shore oil spill, reforestation projects in the Andes...the effects of climate change CURRENT HOT ENVIRONMENTAL ISSUES Growing Environmental Security Issues • Resource conflict: Water resources...problems: Air, water, pandemics Regional Climate Change Effects Adaptation to climate change is a powerful environmental security issue as it threatens

  14. Is Brazil Actually Ready to be a World Economic Power? (CSL Issue Paper, Volume 13-11, July 2011)

    Science.gov (United States)

    2011-07-01

    Brazil, Porto Brasil : Economic Sectors, http://www.brasil.gov.br/sobre/economy/economy-sectors/agriculture-and-cattle- raising-agropecuaria (accessed...April 15, 2011); Federal Government of Brazil, “Porto Brasil : Federal Government Budget,” http://www.brasil.gov.br/sobre/ brazil/government/federal...http://www.reuters.com/assets/print? aid =USN0516532720110405 (accessed April 16, 2011). 23. Ibid. 24 Brian Winters, “Special Report.”

  15. CSL Issue Paper. March 2008, Volume 3-08. New Media and the Warfighter. Workshop Initial Impressions

    National Research Council Canada - National Science Library

    Murphy, Dennis

    2008-01-01

    .... The global information revolution and rapid spread of the internet and other digital media have leveled the playing field between nation-states, non-state actors, multinational corporations and individuals...

  16. Bird Strike Committee Europe (BSCE) , 13th Meeting, Bern, Switzerland 29th May to 2nd June 1978

    National Research Council Canada - National Science Library

    1979-01-01

    ...: Identification of Bird Remains as Part of the Bird Strike Reporting Procedure Birdstrikes - Helicopter in GAF Collisions with Birds of Prey in the Alps The Bird Strike Reporting System in Swiss Air...

  17. Pediatric patients at risk for fever in chemotherapy-induced neutropenia in Bern, Switzerland, 1993-2012

    Science.gov (United States)

    von Allmen, Annina N.; Zermatten, Maxime G.; Leibundgut, Kurt; Agyeman, Philipp; Ammann, Roland A.

    2018-03-01

    Fever in neutropenia (FN) is the most frequent potentially life threatening complication of chemotherapy for cancer. Prediction of the risk to develop FN during chemotherapy would allow for targeted prophylaxis. This retrospective, single centre cohort study in pediatric patients diagnosed with cancer before 17 years covered two decades, 1993 to 2012. The 583 (73%) of 800 patients diagnosed with cancer who had received chemotherapy were studied here. Data on 2113 observation periods was collected, defined by stable combinations of 11 predefined characteristics potentially associated with FN. They covered 692 years of cumulative chemotherapy exposure time, during which 712 FN episodes were diagnosed, 154 (22%) of them with bacteremia. The risk to develop FN and FN with bacteremia remained stable over time. These data can mainly be used to study FN risks over time and between centers, and to derive or externally validate FN risk prediction rules.

  18. "De Genes y Gentes". Libro del Académico Jaime Eduardo Bernál Villegas

    Directory of Open Access Journals (Sweden)

    Francisco Núñez

    2002-08-01

    Full Text Available

    La amistad con Jaime Eduardo Bernal es, además de un permanente disfrute de sus ocurrencias y de su fino humor, un activo ejercicio intelectual. Todavía me asombra su inagotable capacidad de sorprender.

    Es hombre emprendedor, que con tesón ha culminado exitosamente cada uno de los numerosos proyectos que se ha impuesto.

    Así como lo vemos gozar con cada nueva idea, he sido testigo del entusiasmo con que las desarrolla y de su satisfacción cuando las hace realidad.

    Es un médico profundamente compasivo que busca transmitir la armonía que debe existir entre la aplicación del conocimiento, los hallazgos de la ciencia y un ejercicio médico con hondo sentido humanitario.

    Desde que lo conozco (y ello data de los claustros universitarios, ha trabajado infatigablemente por la humanización de la medicina: no es el investigador frío, que se yergue sobre la neutralidad moral de la ciencia o la invoca para apartarse de su compromiso hipocrático. Tiene muy claros los límites que le impone la moral natural y por consiguiente la ética médica Iniciando el año de 1980, recién llegado de Newcastle, Inglaterra, donde acababa de recibir su PhD en Genética Humana después de largos años de especialización, ingresó a la sala de profesores del departamento de Pediatría de la Universidad Javeriana, donde solíamos reunirnos a debatir los casos clínicos de nuestros pacientes. Jaime Eduardo entró calmadamente, en su mano un maletín y en él una libreta que llamaba “el libro de las Ideas” y así estaba rotulada; se hallaban consignados allí muchos de los que habrían de convertirse en proyectos de investigación y más tarde en exitosas investigaciones y publicaciones.

    Ocupó un escritorio y me dijo “vamos a ver qué se puede hacer, vengo a pensar…“. No había transcurrido mucho tiempo cuando sus ideas y alrededor de ellas un pequeño grupo de investigadores ya nos habían desalojado de nuestra sala de profesores; meses después ocupó un área aledaña al laboratorio clínico del hospital de San Ignacio que, al poco tiempo, fue también insuficiente para albergarlo, con todas sus ideas y proyectos en vigoroso desarrollo; se percibía allí una actividad permanente, llena del entusiasmo que caracteriza cada sueño que Bernal quiere hacer real...

  19. Mont Terri Project - Heater experiment, engineered barriers emplacement and ventilations tests. No 1 - Swiss Geological Survey, Bern, 2007

    International Nuclear Information System (INIS)

    Bossart, P.; Nussbaum, C.

    2007-01-01

    The international Mont Terri project started in January 1996. Research is carried out in the Mont Terri rock laboratory, an underground facility near the security gallery of the Mont Terri motorway tunnel (vicinity of St-Ursanne, Canton of Jura, Switzerland). The aim of the project is the geological, hydrogeological, geochemical and geotechnical characterisation of a clay formation, specifically of the Opalinus Clay. Twelve Partners from European countries and Japan participate in the project. These are ANDRA, BGR, CRIEPI, ENRESA, GRS, HSK, IRSN, JAEA, NAGRA, OBAYASHI, SCK.CEN and swisstopo. Since 2006, swisstopo acts as operator of the rock laboratory and is responsible for the implementation of the research programme decided by the partners. The three following reports are milestones in the research history of the Mont Terri project. It was the first time that an in-situ heating test with about 20 observation boreholes over a time span of several years was carried out in a clay formation. The engineered barrier emplacement experiment has been extended due to very encouraging measurement results and is still going on. The ventilation test was and is a challenge, especially in the very narrow microtunnel. All three projects were financially supported by the European Commission and the Swiss State Secretariat for Education and Research. The three important scientific and technical reports, which are presented in the following, have been provided by a number of scientists, engineers and technicians from the Partners, but also from national research organisations and private contractors. Many fruitful meetings where held, at the rock laboratory and at other facilities, not to forget the weeks and months of installation and testing work carried out by the technicians and engineers. The corresponding names and organisations are listed in detail in the reports. Special thanks are going to the co-ordinators of the three projects for their motivation of the team during planning, instrumentation, testing and interpretation. These are Juan Carlos Mayor and Fernando Huertas from ENRESA, and lngeborg Goebel from BGR. We would also like to warmly thank Christopher Davies from the European Commission for his endurable support of the three projects. Finally, we would like to express our thanks to all Mont Terri Partners for their excellent collaboration and the federal and cantonal authorities for their support in the project. The authors accept sole responsibility for the content of the reports. Further information on the Mont Terri project can be found on the web site www.mont-terri.ch. (author)

  20. Strategic Minerals: Is China’s Consumption a Threat to United States Security? (CSL Issue Paper, Volume 7-11, July 2011)

    Science.gov (United States)

    2011-07-01

    approximately $50 billion in energy agreements with Brazil , Russia, Venezuela and Kazakhstan (Jiang 2009). Because Southern Africa contains major reserves of...building football stadiums for governments, China has moved aggressively to tie up mineral concessions in Africa. In 2008 China signed a long-term

  1. When is it acceptable to kill a strictly protected carnivore : Exploring the legal constraints on wildlife management within Europe's Bern Convention

    NARCIS (Netherlands)

    Linnell, John; Trouwborst, Arie; Fleurke, Floor

    2017-01-01

    As wolf populations expand across Europe, many countries face challenges in finding ways to address the concerns of some elements among the rural stakeholders who are being asked to share their landscapes with wolves for the first time in several generations. In these recovery landscapes, wolves are

  2. Water nuisance and road safety : paper presented to Session II of 1978 OECD Symposium on Road Drainage, Berne, Switzerland, 22-24 May, 1978.

    NARCIS (Netherlands)

    Welleman, A.G.

    1978-01-01

    Factors that may contribute to accidents on wet road surfaces (reduced general visibility, glare, invisibility of markings and reduction of tyre/road surface forces) are discussed in particular the latter. Measures for counteracting water nuisance (cutting grooves, small transverse discharge

  3. Measuring oral health-related quality-of-life using OHQoL-GE in periodontal patients presenting at the University of Berne, Switzerland.

    Science.gov (United States)

    Aslund, Madeleine; Pjetursson, Bjarni E; Lang, Niklaus P

    2008-01-01

    To assess the impact of oral health related quality-of-life (OHQoL) on patients presenting at the Department of Periodontology and Fixed Prosthodontics using a German version (the OHQoL-GE) of the oral health-related quality-of-life in the UK (OHQoL-UK) questionnaire. A total of 251 patients were invited to fill out the OHQoL-GE. In addition, patients were given a checklist of dental-related items over the past year including 'tooth ache', 'dental treatment', 'bleeding gums', 'swollen gums' and 'problems with dental prosthesis'. Prior to being seen by a dental professional, the patients completed the questionnaires. During the new patient clinic visit, medical and dental history, age, gender, number of teeth present and presence or absence and type of dental prosthesis were recorded. In addition, a basic periodontal examination (BPE) was performed. Two hundred and fifteen OHQoL-GE questionnaires were completed. OHQoL-GE scores were significantly associated with patients' self-reported symptoms and problems in the past year: experiences of 'tooth ache' (P periodontal and prosthetic status, number of teeth present and age impact on quality-of-life. This has implications in understanding the consequences of dental health and in the use of patient-centred outcomes in dental research. The OHQoL-GE demonstrates discriminative validity in a population seeking dental advice and/or treatment.

  4. A survey of plant and algal genomes and transcriptomes reveals new insights into the evolution and function of the cellulose synthase superfamily

    Science.gov (United States)

    2014-01-01

    Background Enzymes of the cellulose synthase (CesA) family and CesA-like (Csl) families are responsible for the synthesis of celluloses and hemicelluloses, and thus are of great interest to bioenergy research. We studied the occurrences and phylogenies of CesA/Csl families in diverse plants and algae by comprehensive data mining of 82 genomes and transcriptomes. Results We found that 1) charophytic green algae (CGA) have orthologous genes in CesA, CslC and CslD families; 2) liverwort genes are found in the CesA, CslA, CslC and CslD families; 3) The fern Pteridium aquilinum not only has orthologs in these conserved families but also in the CslB, CslH and CslE families; 4) basal angiosperms, e.g. Aristolochia fimbriata, have orthologs in these families too; 5) gymnosperms have genes forming clusters ancestral to CslB/H and to CslE/J/G respectively; 6) CslG is found in switchgrass and basal angiosperms; 7) CslJ is widely present in dicots and monocots; 8) CesA subfamilies have already diversified in ferns. Conclusions We speculate that: (i) ferns and horsetails might both have CslH enzymes, responsible for the synthesis of mixed-linkage glucans and (ii) CslD and similar genes might be responsible for the synthesis of mannans in CGA. Our findings led to a more detailed model of cell wall evolution and suggested that gene loss played an important role in the evolution of Csl families. We also demonstrated the usefulness of transcriptome data in the study of plant cell wall evolution and diversity. PMID:24708035

  5. Assessing the effect of leachate of copper slag from the ISASMELT process on cell growth and proximate components in microalgae, Chlorella vulgaris (Beijerinck)

    Digital Repository Service at National Institute of Oceanography (India)

    Harish, V.; Sreepada, R.A.; Suryavanshi, U.; Shanmuganathan, P.; Sumathy, A.

    vulgaris (Beijerinck), were assessed under laboratory conditions. An inhibitory effect of CSL on cell growth (14.3%) was well below the defined criteria of 50% using algal growth inhibition test. Cellular concentrations of the total protein (TP) in CSL...

  6. Model Checking Algorithms for CTMDPs

    DEFF Research Database (Denmark)

    Buchholz, Peter; Hahn, Ernst Moritz; Hermanns, Holger

    2011-01-01

    Continuous Stochastic Logic (CSL) can be interpreted over continuoustime Markov decision processes (CTMDPs) to specify quantitative properties of stochastic systems that allow some external control. Model checking CSL formulae over CTMDPs requires then the computation of optimal control strategie...

  7. The barley (Hordeum vulgare) cellulose synthase-like D2 gene (HvCslD2) mediates penetration resistance to host-adapted and nonhost isolates of the powdery mildew fungus

    NARCIS (Netherlands)

    Douchkov, Dimitar; Lueck, Stefanie; Hensel, Goetz; Kumlehn, Jochen; Rajaraman, Jeyaraman; Johrde, Annika; Doblin, Monika S.; Beahan, Cherie T.; Kopischke, Michaela; Fuchs, René; Lipka, Volker; Niks, Rients E.; Bulone, Vincent; Chowdhury, Jamil; Little, Alan; Burton, Rachel A.; Bacic, Antony; Fincher, Geoffrey B.; Schweizer, Patrick

    2016-01-01

    Cell walls and cellular turgor pressure shape and suspend the bodies of all vascular plants. In response to attack by fungal and oomycete pathogens, which usually breach their host's cell walls by mechanical force or by secreting lytic enzymes, plants often form local cell wall appositions

  8. contribution to study the glycoprotein ligands of the cerebellar ...

    African Journals Online (AJOL)

    H. Rechreche and J.P. Zanetta

    2016-09-01

    Sep 1, 2016 ... SDS-PAGE and revelation with CBB or silver nitrate. Finally, the Bio-CSL activity was ... vacuum centrifuge, the pellets thus obtained were included in 20 µl H2O and aliquots (1 µl) were deposited onto a .... SDS-PAGE (silver staining); B: Western blot (CSL ligands revealed with Bio-CSL and avidin-AKP). a) ...

  9. Institutional Logics and Community Service-Learning in Higher Education

    Science.gov (United States)

    Taylor, Alison; Kahlke, Renate

    2017-01-01

    This paper explores how community service-learning (CSL) participants negotiate competing institutional logics in Canadian higher education. Drawing theoretically from new institutionalism and work on institutional logics, we consider how CSL has developed in Canadian universities and how participants discuss CSL in relation to other dominant…

  10. Measures to increase traffic law acceptance : some strategic considerations. Paper presented at the 5th European workshop `New developments in traffic safety research', Bern, May 2-3, 1996.

    NARCIS (Netherlands)

    Goldenbeld, C.

    1997-01-01

    The set of traffic laws and rules intends to maximise the possibilities for free movement in the traffic system, while at the same time safeguarding road safety. Acceptance of traffic laws depends in part on properties of the laws and rules themselves that determine how they will be perceived or

  11. Critical service learning in community health nursing: enhancing access to cardiac health screening.

    Science.gov (United States)

    Gillis, Angela; Mac Lellan, Marian A

    2013-04-23

    Critical service learning (CSL) offers promise for preparing community health nursing students to be advocates for social justice and social change. The purpose of this article is to describe a community based CSL project designed to provide cardiac health screening to an underserviced population, wherein nursing's role in social justice is integrated into nursing practice. First, the relationship between social justice and CSL is explored. Then, the CSL approach is examined and differentiated from the traditional service learning models frequently observed in the nursing curriculum. The CSL project is described and the learning requisites, objectives, requirements, and project outcomes are outlined. While not a panacea for system reform, CSL offers nursing students avenues for learning about social justice and understanding the social conditions that underlie health inequalities. Nurse educators may benefit from the new strategies for incorporating social justice into nursing curriculum; this paper suggests that CSL offers one possibility.

  12. Enhanced laccase production by Trametes versicolor using corn steep liquor as both nitrogen source and inducer.

    Science.gov (United States)

    Wang, Feng; Hu, Jian-Hua; Guo, Chen; Liu, Chun-Zhao

    2014-08-01

    A highly efficient strategy for laccase production by Trametes versicolor was developed using corn steep liquor (CSL) as both a nitrogen source and a laccase inducer. At the optimal CSL concentration of 20 gL(-1), an extracellular laccase activity of 633.3 UL(-1) was produced after a culture period of only 5 days. This represented a 1.96-fold increase relative to control medium lacking CSL. The addition of crude phenolic extracts from CSL improved laccase production to 91.8% greater than the control. Sinapinic acid, present in CSL, caused a reduction in laccase production, vanillic acid and ferulic acid (also present in CSL) synergistically induced laccase production by more than 100% greater than the control medium. Vanillic acid and ferulic acid provided the main contribution to the enhancement of laccase production. This study provides a basis for understanding the induction mechanism of CSL for laccase production. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Chickpea (Cicer arietinum steep liquor as a leavening agent: Effect on dough rheology and sensory properties of bread

    Directory of Open Access Journals (Sweden)

    Saad Ahmed M.

    2015-01-01

    Full Text Available Dough fermentation is one of the oldest process in food technologies. It has been recently intensively studied for its impact on the sensory, structural, nutritional and shelf life properties of leavened baked products. The goals of this work were to investigate chickpea steep liquor (CSL as a dough-leavening agent and to study the effect of CSL on the dough rheology and sensory properties of leavened bread. CSL was prepared by submerging chickpea seeds in boiled distilled water (1:2, w/v for 24 h at 37оC, and then obtained liquor was filtered and freeze-dried to obtain CSL. The addition of CSL to wheat flour (WF brought changes in the dough mixing behavior as measured by the farinograph. An increase in the farinograph water absorption of WF dough was observed when 4.5% CSL and 1.5% yeast was added, while arrival time was not affected. Addition of CSL to the dough at a content of 4.5, 9.0 and 13.5 g CSL/300 g WF caused an increase in dough stability. The CSL addition also increased mechanical tolerance index, dough weakening and mixing time. Dough development time for all blends was higher than the control (1.2-1.5 min, while between the CSL samples no significant difference was observed. The loaf weight slightly increased from 146.2 g for control to 152.2 g for CSL fermented bread, whereas the loaf volume and specific volume of CSL-fermented bread were lower than the control. The combination of yeast and CSL increased the acceptability of bread with the increasing level of both leavening agents’. The results show that CSL could be used as an alternative to yeast for syngas fermentation. On the other hand, CLS is rich in nutrients and lower in cost compared to yeast.

  14. Chlamydia control in Europe - a survey of Member States

    DEFF Research Database (Denmark)

    Andersen, Berit; van Bergen, J; Ward, H

    ), contributed to the design and interpretation of the survey, commented on the draft report and approved the final report. Shelagh Redmond (Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland) provided technical support. Nicola Low (University of Bern) led the Chlamydia Control...

  15. The cellulose synthase superfamily in fully sequenced plants and algae

    Directory of Open Access Journals (Sweden)

    Xu Ying

    2009-07-01

    Full Text Available Abstract Background The cellulose synthase superfamily has been classified into nine cellulose synthase-like (Csl families and one cellulose synthase (CesA family. The Csl families have been proposed to be involved in the synthesis of the backbones of hemicelluloses of plant cell walls. With 17 plant and algal genomes fully sequenced, we sought to conduct a genome-wide and systematic investigation of this superfamily through in-depth phylogenetic analyses. Results A single-copy gene is found in the six chlorophyte green algae, which is most closely related to the CslA and CslC families that are present in the seven land plants investigated in our analyses. Six proteins from poplar, grape and sorghum form a distinct family (CslJ, providing further support for the conclusions from two recent studies. CslB/E/G/H/J families have evolved significantly more rapidly than their widely distributed relatives, and tend to have intragenomic duplications, in particular in the grape genome. Conclusion Our data suggest that the CslA and CslC families originated through an ancient gene duplication event in land plants. We speculate that the single-copy Csl gene in green algae may encode a mannan synthase. We confirm that the rest of the Csl families have a different evolutionary origin than CslA and CslC, and have proposed a model for the divergence order among them. Our study provides new insights about the evolution of this important gene family in plants.

  16. Community Service Learning as Critical Curriculum: Promoting International Students' Second Language Practices

    Science.gov (United States)

    Chao, Xia

    2016-01-01

    Grounded in the whole person perspective of language learners and the concepts of investment and L2 socialization, this qualitative study explores how community service learning (CSL) contributes to international students' L2 practices and identity development. This study finds that CSL creates "a pedagogical contact zone" outside the…

  17. Bisimulation and Logical Preservation for Continuous-Time Markov Decision Processes

    NARCIS (Netherlands)

    Neuhausser, M.; Katoen, Joost P.

    This paper introduces strong bisimulation for continuous-time Markov decision processes (CTMDPs), a stochastic model which allows for a nondeterministic choice between exponential distributions, and shows that bisimulation preserves the validity of CSL. To that end, we interpret the semantics of CSL

  18. Production of thermophilic and acidophilic endoglucanases by ...

    African Journals Online (AJOL)

    The effect of the carbon (sugarcane bagasse: SCB) and nitrogen (corn steep liquor: CSL) sources on endoglucanase production by the mutants 102C1 and 104C2 was studied using submerged cultivations at 28°C. Different concentrations of SCB and CSL were used and nine different media were generated. Mutant 102C1 ...

  19. U.S. Veteran Health Care Utilization Increases after Caregivers' Use of National Caregiver Telephone Support Line.

    Science.gov (United States)

    Griffin, Joan M; Malcolm, Cari; Wright, Pamela; Hagel Campbell, Emily; Kabat, Margaret; Bangerter, Ann K; Sayer, Nina A

    2017-05-01

    The U.S. Department of Veterans Affairs (VA) established the national Caregiver Support Line (CSL) in February 2011. The CSL is operated by licensed master's degree social workers who provide caregivers of veterans with information about caregiver benefits and services, counseling, and referrals to a caregiver support coordinator at the nearest VA medical center. The authors compared differences in veteran health care utilization patterns in the six months before and after a caregiver call to the CSL, hypothesizing that veterans with caregivers using the CSL had improved access to health care services and improved access increased utilization of health care. A pre- and posttest design was used. CSL calls that resulted in referrals to VA health care services or to local VA caregiver support coordinators were included in the sample. Data were extracted from the CSL database and matched to veteran care utilization data using veteran medical record data. Veteran inpatient stays for general medicine, hospice, respite, and long-term care significantly increased after the CSL call, but other inpatient stays (surgery, neurology) did not. Outpatient services for home health, respite, and mental health all significantly increased. Caregivers' use of the national CSL may help facilitate access for veterans to needed care services. © 2017 National Association of Social Workers.

  20. Optimization of liquid-liquid extraction of biosurfactants from corn steep liquor.

    Science.gov (United States)

    Vecino, X; Barbosa-Pereira, L; Devesa-Rey, R; Cruz, J M; Moldes, A B

    2015-09-01

    In this work, the optimization of the operational conditions for the chloroform-based extraction of surface-active compounds from corn steep liquor (CSL) was carried out and the nutritional properties of the remnant aqueous phase (CSL-less biosurfactant) was evaluated as microbial fermentation medium. The optimal conditions to obtain biosurfactants from CSL were as follows: chloroform/CSL ratio 2 (v/v), 56 °C at extraction times >30 min. At the optima conditions, 100 % of biosurfactant extract can be obtained from CSL, obtaining 12.0 ± 0.5 g of biosurfactant extract/Kg of CSL. The critical micelle concentration (CMC) of the biosurfactant extract was 399.4 mg L(-1). This value is similar to the CMC of cetrimonium bromide (CTAB), a cationic surfactant used in the formulation of nanoparticles. The extraction of biosurfactant can be also carried out at room temperature although in this case, the extraction yield decreased about 15 %. The extraction of surface-active compounds from agroindustrial streams can suppose important advances for the bio-based surfactants industry. Biosurfactants obtained in this work are not only more eco-friendly than chemical detergents but also can be cost competitive with its chemical counterparts. Furthermore, after the extraction of surface-active compounds, CSL-less biosurfactant was found to be suitable as nutritional supplement for lactic acid bacteria, maintaining its nutritional properties in comparison with regular CSL.

  1. Journalism that Matters: Views from Central and Eastern Europe. By Michał Głowacki, Epp Lauk and Auksė Balčytienė. Bern: Peter Lang, 2014, 214 pp.; ISBN: 978-3-631-65421-7 hb.

    Directory of Open Access Journals (Sweden)

    Elena Rodina

    2015-12-01

    Full Text Available This book is a much-needed contribution to journalistic studies that allows us to have a closer and more nuanced look at media systems and press cultures in the countries of Central and Eastern Europe (CEE from a non-Western perspective. The volume is of high value to anyone who is interested in the diversity that underlies the unifying term of “post-communist media.” Most of its authors rely on rich data collected throughout lengthy periods of time on the territory of Central and Eastern Europe, which allows us to see not only the current state of “Eastern” media, but its development throughout time.

  2. Berní zatížení českého venkova v první polovině 19. století a úskalí jeho studia // The tax burden on the Czech countryside in the first half of the 19th century and some pitfalls in its studies

    Directory of Open Access Journals (Sweden)

    Jan Lhoták

    2017-08-01

    Full Text Available The paper summarises the possibilities of studying the tax burden on the Czech countryside in 1780–1850. For its analysis it proposes to use the archival collection ‘Contribution Funds’, consisting of individual schedules for the planned contributions (so-called sub-repartitions, and contributory accounts recording all receipts and outlays. Due to the limited ‘sub-repartition’ for land tax only, it recommends to use the sums in the contributory accounts and to work with values for the whole estate. The most suitable comparative figures are grain prices, preserved from commodity prices that are important for the rural environment in the most comprehensive price ranges. Both series of numbers need to be subjected to source criticism (the most important for the period under review is the variability of the currencies used and then compared with each other.

  3. Current spreading in GaN-based light-emitting diodes

    International Nuclear Information System (INIS)

    Li Qiang; Li Yufeng; Ding Wen; Yun Feng; Zhang Minyan

    2016-01-01

    We have investigated the factors affecting the current spreading length (CSL) in GaN-based light-emitting diodes (LEDs) by deriving theoretical expressions and performing simulations with APSYS. For mesa-structure LEDs, the effects of both indium tin oxide (ITO) and n-GaN are taken into account for the first time, and a new Q factor is introduced to explain the effects of different current flow paths on the CSL. The calculations and simulations show that the CSL can be enhanced by increasing the thickness of the ITO layer and resistivity of the n-GaN layer, or by reducing the resistivity of the ITO layer and thickness of the n-GaN layer. The results provide theoretical support for calculating the CSL clearly and directly. For vertical-structure LEDs, the effects of resistivity and thickness of the CSL on the internal quantum efficiency (IQE) have been analyzed. The theoretical expression relating current density and the parameters (resistivity and thickness) of the CSL is obtained, and the results are then verified by simulation. The IQE under different current injection conditions is discussed. The effects of CSL resistivity play a key role at high current injection, and there is an optimal thickness for the largest IQE only at a low current injection. (paper)

  4. Profiling Perceptual Learning Styles of Chinese as a Second Language Learners in University Settings.

    Science.gov (United States)

    Sun, Peijian Paul; Teng, Lin Sophie

    2017-12-01

    This study revisited Reid's (1987) perceptual learning style preference questionnaire (PLSPQ) in an attempt to answer whether the PLSPQ fits in the Chinese-as-a-second-language (CSL) context. If not, what are CSL learners' learning styles drawing on the PLSPQ? The PLSPQ was first re-examined through reliability analysis and confirmatory factor analysis (CFA) with 224 CSL learners. The results showed that Reid's six-factor PLSPQ could not satisfactorily explain the CSL learners' learning styles. Exploratory factor analyses were, therefore, performed to explore the dimensionality of the PLSPQ in the CSL context. A four-factor PLSPQ was successfully constructed including auditory/visual, kinaesthetic/tactile, group, and individual styles. Such a measurement model was cross-validated through CFAs with 118 CSL learners. The study not only lends evidence to the literature that Reid's PLSPQ lacks construct validity, but also provides CSL teachers and learners with insightful and practical guidance concerning learning styles. Implications and limitations of the present study are discussed.

  5. Effect of corn steep liquor on lettuce root rot (Fusarium oxysporum f.sp. lactucae) in hydroponic cultures.

    Science.gov (United States)

    Chinta, Yufita D; Kano, Kazuki; Widiastuti, Ani; Fukahori, Masaru; Kawasaki, Shizuka; Eguchi, Yumi; Misu, Hideyuki; Odani, Hiromitsu; Zhou, Songying; Narisawa, Kazuhiko; Fujiwara, Kazuki; Shinohara, Makoto; Sato, Tatsuo

    2014-08-01

    Recent reports indicate that organic fertilisers have a suppressive effect on the pathogens of plants grown under hydroponic systems. Furthermore, microorganisms exhibiting antagonistic activity to diseases have been observed in organic hydroponic systems. This study evaluated the effect of corn steep liquor (CSL) on controlling lettuce root rot disease [Fusarium oxysporum f.sp. lactucae (FOL)] in a hydroponic system. The effect of CSL and Otsuka A (a chemical fertiliser) on the inhibition of FOL in terms of mycelial growth inhibition was tested in vivo. Addition of CSL suppressed FOL infection rates. CSL inhibited FOL infection by 26.3-42.5% from 2 days after starting incubation. In comparison, Otsuka A inhibited FOL growth by 5.5-19.4%. In addition, four of 10 bacteria isolated from the nutrient media containing CSL exhibited inhibition zones preventing FOL mycelial growth. We found that CSL suppressed FOL in lettuce via its antifungal and biostimulatory effects. We suggest that activation of beneficial microorganisms present in CSL may be used to decrease lettuce root rot disease and contribute to lettuce root growth. © 2014 Society of Chemical Industry.

  6. Natural and anthropogenic influences on depositional architecture of the Ural Delta, Kazakhstan, northern Caspian Sea, during the past 70 years

    Science.gov (United States)

    Scarelli, Frederico M.; Cantelli, Luigi; Barboza, Eduardo G.; Gabbianelli, Giovanni

    2017-05-01

    This paper focuses on the Ural Delta in the northern zone of the Caspian Sea, an area with particular characteristics, where intense influence from anthropogenic and natural factors exists, which acts on the fragile delta system. We built a database to integrate the data from the published sources, bathymetric survey, and recent images in the geographical information system (GIS) environment. The results were linked to the Caspian Sea level (CSL) curve, which had many variations, changing the Ural Delta system's dynamics and in its architecture. In addition, the anthropogenic changes contribute to shaping the actual Ural Delta architecture. Through the link between the results and CSL, we reconstructed an evolution model for the Ural Delta system for the last century and identified three different architectures for the Ural Delta, determined by the energy that acted on the system in the last century and by the anthropogenic changes. This work identifies six different delta phases, which are shaped by CSL changes during the last 70 years and by anthropogenic changes. The delta phases recognized are: i) a Lobate Delta phase, shaped during high CSL before 1935; ii) Natural Elongate Delta 1935-1950 formed during rapid CSL fall; iii) Anthropogenic Elongate Delta 1950-1966, formed during rapid CSL fall and after the Ural-Caspian Sea canal construction, which modified the sedimentary deposition on the delta; iv) Anthropogenic Elongate Delta 1966-1982 shaped during low CSL phase; v) Anthropogenic Elongate Delta 1982-1996 formed during a rapid CSL rise phase; and vi) Anthropogenic Elongate Delta 1996-2009 shaped during high CSL that represent the last phase and actual Ural Delta architecture.

  7. Design and Effectiveness of a Required Pre-Clinical Simulation-based Curriculum for Fundamental Clinical Skills and Procedures

    Directory of Open Access Journals (Sweden)

    Daryl P. Lofaso

    2011-12-01

    Full Text Available For more than 20 years, medical literature has increasingly documented the need for students to learn, practice and demonstrate competence in basic clinical knowledge and skills. In 2001, the Louisiana State University Health Science Centers (LSUHSC School of Medicine – New Orleans replaced its traditional Introduction in to Clinical Medicine (ICM course with the Science and Practice of Medicine (SPM course. The main component within the SPM course is the Clinical Skills Lab (CSL. The CSL teaches 30 plus skills to all pre-clinical medical students (Years 1 and 2. Since 2002, an annual longitudinal evaluation questionnaire was distributed to all medical students targeting the skills taught in the CSL. Students were asked to rate their self- confidence (Dreyfus and Likert-type and estimate the number of times each clinical skill was performed (clinically/non-clinically. Of the 30 plus skills taught, 8 were selected for further evaluation. An analysis was performed on the eight skills selected to determine the effectiveness of the CSL. All students that participated in the CSL reported a significant improvement in self-confidence and in number performed in the clinically/non-clinically setting when compared to students that did not experience the CSL. For example, without CSL training, the percentage of students reported at the end of their second year self-perceived expertise as “novice” ranged from 21.4% (CPR to 84.7% (GU catheterization. Students who completed the two-years CSL, only 7.8% rated their self-perceived expertise at the end of the second year as “novice” and 18.8% for GU catheterization. The CSL design is not to replace real clinical patient experiences. It's to provide early exposure, medial knowledge, professionalism and opportunity to practice skills in a patient free environment.

  8. The Effects of Cassia Siamea Lam. Root Extract on the Corrosion and Kinetics of Corrosion Process of Copper in Alkaline Solutions

    OpenAIRE

    Onen, A. I; Nwufo, B. T.; Ebenso, E. E.

    2011-01-01

    The effect of Cassia siamea lam. (CSL) root extract as a corrosion inhibitor of copper in 0.50 M NaOH solutions was investigated using absorbance difference technique at 30 °C and 40 °C. CSL root extract inhibited the corrosion of copper in 0.50 M NaOH solutions and the inhibition efficiency (% IE) increased to a maximum of 78.3±2.3% with increasing concentration of the extract but decreased with increasing temperature. The adsorption of CSL root extract on copper surface followed the Langmui...

  9. Chiral soliton lattice and charged pion condensation in strong magnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Brauner, Tomáš [Faculty of Science and Technology, University of Stavanger,N-4036 Stavanger (Norway); Yamamoto, Naoki [Department of Physics, Keio University,Yokohama 223-8522 (Japan)

    2017-04-21

    The Chiral Soliton Lattice (CSL) is a state with a periodic array of topological solitons that spontaneously breaks parity and translational symmetries. Such a state is known to appear in chiral magnets. We show that CSL also appears as a ground state of quantum chromodynamics at nonzero chemical potential in a magnetic field. By analyzing the fluctuations of the CSL, we furthermore demonstrate that in strong but achievable magnetic fields, charged pions undergo Bose-Einstein condensation. Our results, based on a systematic low-energy effective theory, are model-independent and fully analytic.

  10. Simulations to save time, money, and lives

    Energy Technology Data Exchange (ETDEWEB)

    Sackett, D.E. [Lawrence Livermore National Lab., CA (United States)

    1996-11-01

    The Laboratory`s Conflict Simulation Laboratory (CSL) has been developing computerized programs to simulate combat and other conflicts since 1974. All branches of the military use these systems for training purposes and to prepare for operations as diverse as the 1989 invasion of Panama and peacekeeping in Somalia. The CSL is presently continuing development of the Joint Tactical Simulation (JTS) and recently began work on the Joint Conflict and Tactical Simulation (JCATS) program for the Joint Chiefs of Staff. The Army is still using the CSL`s first model, Janus.

  11. Functional genomic analysis supports conservation of function among cellulose synthase-like a gene family members and suggests diverse roles of mannans in plants

    DEFF Research Database (Denmark)

    Liepman, Aaron H; Nairn, C Joseph; Willats, William G T

    2007-01-01

    in insect cells, and each CslA protein catalyzed mannan and glucomannan synthase reactions in vitro. Microarray mining and quantitative real-time reverse transcription-polymerase chain reaction analysis demonstrated that transcripts of Arabidopsis and loblolly pine (Pinus taeda) CslA genes display tissue...... they are prevalent at cell junctions and in buds. Taken together, these results demonstrate that members of the CslA gene family from diverse plant species encode glucomannan synthases and support the hypothesis that mannans function in metabolic networks devoted to other cellular processes in addition to cell wall...

  12. semi-dwarf tef lines for high seed yield and lodging tolerance in ...

    African Journals Online (AJOL)

    ACSS

    4Center for Development and Environment (CDE), University of Bern, 3012 Bern, Switzerland. Corresponding author: Zerihun.tadele@ips.unibe.ch. (Received 2 July, 2016; accepted 4 October, 2017). ABSTRACT. Tef [Eragrostis tef (Zucc.) Trotter] is the major cereal crop in the Horn of Africa, especially in Ethiopia where it.

  13. Effect of Fertilization on Growth and Wood Properties of Thinned and Un-thinned Mid-rotation Loblolly Pine (Pinus taeda L.) Stands

    Science.gov (United States)

    Finto Antony; Laurence R. Schimleck; Richard F. Daniels; Alexander Clark

    2011-01-01

    Growth and wood properties were measured on breast height cores collected from two stands, New Bern and Bertie, located in the lower Coastal Plain of North Carolina. The New Bern site was thinned before fertilizer application, and the Bertie site was not. The study was laid out in a randomized complete block design with each treatment replicated in four blocks at New...

  14. Einstein and the Special Theory of Relativity

    Indian Academy of Sciences (India)

    ANew Point of View. Einstein formulated the special theory of relativity during his tenure at the Swiss Patent Office at Berne. In the words of. Martin Klein: "In his spare time during those years at Berne, the young patent examiner wrought a series of scientific miracles; no weaker word is adequate. He did nothing less than to ...

  15. Séminaire de physique corpusculaire | 27 February

    CERN Multimedia

    2013-01-01

      The new Bern cyclotron laboratory for PET radioisotope production and its beam line for multi-disciplinary research, by Dr Saverio Braccini, Albert Einstein Center for Fundamental Physics, University of Bern. Wednesday 27 February 2013 at 11:15 Science III, Auditoire 1S081 30, quai Ernest-Ansermet, 1211 Genève 4 Abstract: The new Bern cyclotron laboratory is based on a 18 MeV proton cyclotron equipped with a specifically conceived 6 m long research beam line, terminated in a separate bunker. This particular configuration is designed for industrial Positron Emission Tomography (PET) radioisotope production as well as for novel detector, radiation biophysics, radiation protection, materials science, radiochemistry and radiopharmacy scientific activities. This project is the result of the successful collaboration among the University Hospital in Bern (Inselspital), the University of Bern, private investors and industrial partners. This new facility is now operational and open to nation...

  16. Primary User Localization Algorithm Based on Compressive Sensing in Cognitive Radio Networks

    Directory of Open Access Journals (Sweden)

    Fang Ye

    2016-04-01

    Full Text Available In order to locate source signal more accurately in authorized frequency bands, a novel primary user localization algorithm based on compressive sensing (PU-CSL in cognitive radio networks (CRNs is proposed in this paper. In comparison to existing centroid locating algorithms, PU-CSL shows higher locating accuracy for integrally exploring correlation between source signal and secondary users (SUs. Energy detection is first adopted for collecting the energy fingerprint of source signal at each SU, then degree of correlation between source signal and SUs is reconstructed based on compressive sensing (CS, which determines weights of centroid coordinates. A weighted centroid scheme is finally utilized to estimate source position. Simulation results show that PU-CSL has smaller maximum error of positioning and root-mean-square error. Moreover, the proposed PU-CSL algorithm possess excellent location accuracy and strong anti-noise performance.

  17. Quality assurance plan for the Close Support Laboratory for the remedial investigation at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1993-08-01

    The primary purpose of the Close Support Laboratory (CSL) is to provide rapid radiological screening of investigation-derived samples before they are shipped to off-site laboratories for more detailed analyses. Analyses for volatile organic compounds and miscellaneous water quality parameters are also performed at the CSL. CSL data are also used to select samples for off-site laboratory analysis, for rapid qualitative and quantitative determinations, and for other processes when off-site analysis is not needed and/or is impractical. This plan specifies methods of implementing analytical and radiological protocols and procedures for the documentation, handling, control, and analysis of samples and describes the levels of authority and responsibility for laboratory operation. Specific quality control methods used by the CSL for individual analyses are described in project procedures

  18. Arabidopsis CDS blastp result: AK242585 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK242585 J090010M20 At3g03050.1 68416.m00301 cellulose synthase family protein (CslD3) similar to cellulose... synthase catalytic subunit gi:2827143 from [Arabidopsis thaliana], cellulose syntha

  19. Arabidopsis CDS blastp result: AK242601 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK242601 J090014G03 At3g03050.1 68416.m00301 cellulose synthase family protein (CslD3) similar to cellulose... synthase catalytic subunit gi:2827143 from [Arabidopsis thaliana], cellulose syntha

  20. Arabidopsis CDS blastp result: AK110467 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK110467 002-166-G08 At3g03050.1 cellulose synthase family protein (CslD3) similar to cellulose... synthase catalytic subunit gi:2827143 from [Arabidopsis thaliana], cellulose synthase-7 (gi:962

  1. Arabidopsis CDS blastp result: AK242890 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK242890 J090079L19 At3g03050.1 68416.m00301 cellulose synthase family protein (CslD3) similar to cellulose... synthase catalytic subunit gi:2827143 from [Arabidopsis thaliana], cellulose syntha

  2. The Collins Center Update. Volume 1, Issue 3, December 1999

    National Research Council Canada - National Science Library

    Harvey, Kevin; Wasiak, Joe; Kievit, James; Griffard, B. F; Blotzer, Larry

    1999-01-01

    ...: Kentucky Governor Patton Kicks Off the Center for Strategic Leadership's (CSL) Senior Executive Program, Global Guardian Exercise '99, Global Wargame '99, Democratization Initiatives Support Simulation, Deterrence in the 21st Century Symposium...

  3. A calsequestrin-like protein in the endoplasmic reticulum of the sea urchin: localization and dynamics in the egg and first cell cycle embryo

    OpenAIRE

    1989-01-01

    Using an antiserum produced against a purified calsequestrin-like (CSL) protein from a microsomal fraction of sea urchin eggs, we performed light and electron microscopic immunocytochemical localizations on sea urchin eggs and embryos in the first cell cycle. The sea urchin CSL protein has been found to bind Ca++ similarly to calsequestrin, the well-characterized Ca++ storage protein in the sarcoplasmic reticulum of muscle cells. In semi-thin frozen sections of unfertilized eggs, immunofluore...

  4. Misorientation characteristics of penetrating morphologies at the growth front of abnormally growing grains in aluminum alloy

    Science.gov (United States)

    Park, Chang-Soo; Na, Tae-Wook; Park, Hyung-Ki; Kim, Dong-Kyun; Han, Chan-Hee; Hwang, Nong-Moon

    2012-07-01

    The initial stage of abnormal grain growth of the aluminum alloy 5052 has been investigated using electron back-scattered diffraction to analyze the characteristic of misorientations of the penetrating morphology at the growth front. Among the 84 penetrating morphologies examined, none of the penetrated grain boundaries has low angles or coincidence site lattice (CSL) relations, whereas 66 penetrating grain boundaries have low angles or CSL relations. These results strongly suggest that the penetrating morphologies should result from triple-junction wetting.

  5. Reversal of memory deficits by Coriandrum sativum leaves in mice.

    Science.gov (United States)

    Mani, Vasudevan; Parle, Milind; Ramasamy, Kalavathy; Abdul Majeed, Abu Bakar

    2011-01-15

    Coriandrum sativum L., commonly known as coriander and belonging to the family Apiaceae (Umbelliferae), is cultivated throughout the world for its nutritional value. The present study was undertaken to investigate the effects of fresh Coriandrum sativum leaves (CSL) on cognitive functions, total serum cholesterol levels and brain cholinesterase activity in mice. In this study, CSL (5, 10 and 15% w/w of diet) was fed orally with a specially prepared diet for 45 days consecutively to experimental animals. Elevated plus-maze and passive avoidance apparatus served as the exteroceptive behavioral models for testing memory. Diazepam, scopolamine and ageing-induced amnesia served as the interoceptive behavioral models. CSL (5, 10 and 15% w/w of diet) produced a dose-dependent improvement in memory scores of young as well as aged mice. CSL also reversed successfully the memory deficits induced by scopolamine (0.4 mg kg(-1), i.p.) and diazepam (1 mg kg(-1), i.p.). Interestingly, brain cholinesterase activity and serum total cholesterol levels were considerably reduced by CSL administration in daily diets concomitantly for 45 days. CSL may be a useful remedy in the management of Alzheimer's disease on account of its multifarious effects such as, memory-improving property, cholesterol-lowering property and anticholinesterase activity. Copyright © 2010 Society of Chemical Industry.

  6. What are driving the long-term Caspian Sea level change?

    Science.gov (United States)

    Chen, J.

    2017-12-01

    Caspian Sea level (CSL) has undergone substantial fluctuations during the past several hundred years. The causes over the entire historical period are uncertain, but we investigate here large changes seen in the past several decades. We use climate model predicted precipitation (P), evaporation (E), and observed river runoff (R) to reconstruct long-term CSL changes for 1979-2015, and show that PER (P-E+R) flux predictions agree very well with observed CSL changes. The observed rapid CSL increase (about 12.74 cm/yr) and significant drop ( -6.72 cm/yr) during the periods 1979-1995 and 1996-2015 are well accounted for by integrated PER flux predictions of +12.38 and -6.79 cm/yr, respectively. We show that increased evaporation rates over the Caspian Sea play a dominant role in reversing the increasing trend in CSL during the past 37 years. The current long-term decline in CSL is expected to continue into the foreseeable future, under global warming scenarios.

  7. Hybrid Cross-Linked Lipase Aggregates with Magnetic Nanoparticles: A Robust and Recyclable Biocatalysis for the Epoxidation of Oleic Acid.

    Science.gov (United States)

    Cui, Jiandong; Cui, Lili; Jia, Shiru; Su, Zhiguo; Zhang, Songping

    2016-09-28

    Highly stable and easily recyclable hybrid magnetic cross-linked lipase aggregates (HM-CSL-CLEAs) were prepared by coaggregation of lipase aggregates with nonfunctionalized magnetic nanoparticles and subsequent chemical cross-linking with glutaraldehyde. Analysis by SEM and CLSM indicated that the CLEAs were embedded in nanoparticle aggregates instead of covalently immobilized. The resulting HM-CSL-CLEAs exhibited higher thermostability, storage stability, and reusability than standard CLEAs. For example, HM-CSL-CLEAs maintained >60% of their initial activity after 40 min of incubation at 60 °C, whereas standard CLEAs lost most of their activities. The HM-CSL-CLEAs can be easily recovered from the reaction mixture by an external magnetic field. Moreover, the H2O2 tolerance of the lipase in HM-CSL-CLEAs was also enhanced, which could relieve the inhibitory effect on lipase activity. A high conversion yield (55%) for the epoxidation of oleic acid using H2O2 as oxidizing agent was achieved by HM-CSL-CLEAs.

  8. Study of the surfactant properties of aqueous stream from the corn milling industry.

    Science.gov (United States)

    Vecino, X; Barbosa-Pereira, L; Devesa-Rey, R; Cruz, J M; Moldes, A B

    2014-06-18

    Corn steep liquor (CSL) is a liquid byproduct generated by the corn wet-milling industry. This agroindustrial residue is obtained when corn is digested with warm water and SO2 in the presence of different spontaneously growing microorganisms. The microbial population of CSL includes lactic acid bacteria, which are widely known to produce biosurfactants. However, there is no information available about the possible existence of surface-active compounds in CSL. In this work the surface tension activity of CSL was evaluated and the biosurfactant contained in this residue was extracted with different organic solvents and characterized. The biosurfactant obtained from CSL was analyzed by Fourier transform infrared spectroscopy, and the composition in fatty acid was analyzed by gas chromatography-mass spectrometry. The hydrophobic chain of the biosurfactant contained in CSL comprised 50-55.2% linolelaidic acid, 15.7-22.2% oleic and/or elaidic acid, 5.9-14.6% stearic acid, and 14.9-19.6% palmitic acid.

  9. Nurturing social responsibility through community service-learning: Lessons learned from a pilot project.

    Science.gov (United States)

    Dharamsi, Shafik; Espinoza, Nancy; Cramer, Carl; Amin, Maryam; Bainbridge, Lesley; Poole, Gary

    2010-01-01

    Community service-learning (CSL) has been proposed as one way to enrich medical and dental students' sense of social responsibility toward people who are marginalized in society. We developed and implemented a new CSL option in the integrated medical/dental curriculum and assessed its educational impact. Focus groups, individual open-ended interviews, and a survey were used to assess dental students', faculty tutors' and community partners' experiences with CSL. CSL enabled a deeper appreciation for the vulnerabilities that people who are marginalized experience; students gained a greater insight into the social determinants of health and the related importance of community engagement; and they developed useful skills in health promotion project planning, implementation and evaluation. Community partners and faculty tutors indicated that equal partnership, greater collaboration, and a participatory approach to course development are essential to sustainability in CSL. CSL can play an important role in nurturing a purposeful sense of social responsibility among future practitioners. Our study enabled the implementation of an innovative longitudinal course (professionalism and community service) in all 4 years of the dental curriculum.

  10. Hardness prediction of HAZ in temper bead welding by non-consistent layer technique

    International Nuclear Information System (INIS)

    Yu, Lina; Saida, Kazuyoshi; Mochizuki, Masahito; Kameyama, Masashi; Chigusa, Naoki; Nishimoto, Kazutoshi

    2014-01-01

    Based on the experimentally obtained hardness database, the neural network-based hardness prediction system of heat affect zone (HAZ) in temper bead welding by Consistent Layer (CSL) technique has been constructed by the authors. However in practical operation, CSL technique is sometimes difficult to perform because of difficulty of the precise heat input controlling, and in such case non-CSL techniques are mainly used in the actual repair process. Therefore in the present study, the neural network-based hardness prediction system of HAZ in temper bead welding by non-CSL techniques has been constructed through thermal cycle simplification, from the view of engineering. The hardness distribution in HAZ with non-CSL techniques was calculated based on the thermal cycles numerically obtained by finite element method. The experimental result has shown that the predicted hardness is in good accordance with the measured ones. It follows that the currently proposed method is effective for estimating the tempering effect during temper bead welding by non-CSL techniques. (author)

  11. Cricket Club

    CERN Multimedia

    Cricket Club

    2012-01-01

    Bern CC V CERN CC in Bern on Sunday 6th May 2012 The storm clouds gathered over Switzerland this weekend as a CERN XI travelled more in hope than expectation to Bern for our first league game of the season. Despite the gloomy weather forecast the sun shone and Captain Elvin won the toss and put Bern into bat on a damp, soft and tricky wicket. Early success came as D'Mello had the Bern captain caught by D. Ahmed in his second over. This was to prove the only success in the first 20 overs as BERN made light of the pitch and the CERN attack to go into the drinks break on 108-1. CERN came storming out after the break with Elvin making the breakthrough to dismiss the Bern number 2 for 74. D'Mello then came back into the attack and ended up with 4-34 as CERN held their catches and fielded well. Chauduri was in fine form and stormed in to take 3-27. Elvin was tight and economical until he went for 23 in his final over but D. Ahmed mopped up the tail with 2-16 in a fine 4 over spell. CERN...

  12. Complex sclerosing lesions and radial sclerosing lesions on core needle biopsy: Low risk of carcinoma on excision in cases with clinical and imaging concordance.

    Science.gov (United States)

    Nakhlis, Faina; Lester, Susan; Denison, Christine; Wong, Stephanie M; Mongiu, Anne; Golshan, Mehra

    2018-03-01

    Complex or radial sclerosing lesions (CSL/RSL) are uncommon diagnoses on core needle biopsy with a reported upgrade rate ranging between 0% and 23%. As a result, their management remains controversial. In this study, we sought to determine the rate of malignancy on excision for patients with pure CSL/RSL on core biopsy, and to evaluate future breast cancer risk when CSL/RSL is managed without excision. We retrospectively reviewed 118 cases of CSL/RSL diagnosed on image-guided breast biopsies between 2005 and 2014 at our institution. Of 98 analyzed patients, 34 (35%) underwent excision and 64 (65%) were observed. Demographic and clinical variables between excision and observation groups were compared. In excised specimens, factors associated with upgrade to malignancy were evaluated. The median age at diagnosis was 49 years (range, 27-88 years). In the excision group, 3/34 cases were associated with malignancy, an overall upgrade rate of 9%. All malignant cases had core needle biopsies interpreted as discordant and were BIRADS 4B or more on imaging. In the observation group, at a median follow-up of 2.2 years, 3/64 (5%) patients developed ipsilateral cancers, all of which were distant from the index CSL/RSL. In our series, we report a 9% malignancy rate on excision of BIRADS >4C lesions characterized as CSL/RSL on core biopsy. In patients with concordant biopsies and BIRADS 4A or lower lesions who underwent observation, we found a low rate of subsequent ipsilateral cancers. Further studies are needed to confirm that for CSL/RSL in concordant core biopsies and BIRADS 4A or lower, nonpalpable lesions, observation may be a reasonable alternative to excision. © 2017 Wiley Periodicals, Inc.

  13. Nova libro pri interlingvistiko

    Index Scriptorium Estoniae

    2006-01-01

    Rets rmt.: Blanke, Detlev. Interlinguistische Beiträge : zum Wesen und zur Plansprachen / herausgegeben von Sabine Fiedler. Frankfurt/Main, Berlin ; Bern ; Bruxelles ; New York ; Oxford ; Wien : Europäischer Verlag der Wissenschaften Peter Lang

  14. Kunstikriitik Ants Juske sai doktoriks / Neeme Korv

    Index Scriptorium Estoniae

    Korv, Neeme, 1974-

    2003-01-01

    Tartu Kõrgema Kunstikooli rektor Ants Juske kaitses 7. veebruaril Tallinnas Kunstiakadeemias edukalt doktoriväitekirja, juhendajaks oli professor Boris Bernštein ning oponeerisid doktor Altti Kuusamo Soomest ja professor Peeter Tulviste

  15. Energy efficient housing in South Africa. A Research Alliance, CSIR/SUPSI project proposal for energy efficient building (housing) in South Africa

    CSIR Research Space (South Africa)

    Kuchena, J

    2010-02-01

    Full Text Available /SUPSI Project Proposal For Energy Efficient Building (Housing) in South Africa PROJECT TITLE: “Energy Efficient Housing in SA” Presentation: Energy Efficient Housing in SA Background SDC HQ Meeting, Bern, Switzerland 11 February, 2010 Presenter: Dr...

  16. 77 FR 36984 - International Standard-Setting Activities

    Science.gov (United States)

    2012-06-20

    ... stakeholders. The Update is communicated via Listserv, a free electronic mail subscription service for industry... for governmental use. The Committee held its 6th session in Berne, Switzerland, on February 20-24...

  17. 78 FR 9831 - Final Flood Elevation Determinations

    Science.gov (United States)

    2013-02-12

    ... are available for inspection at the Craven County GIS/Mapping Department, 226 Pollock Street, New Bern... County Maps are available for inspection at the Jones County Government Office, 418 Highway 58 North... State Highway 56. [[Page 9837

  18. [Karin Hallas. Das Tallinner Mietshaus. Vom Historismus bis zum Jugendstil] / Paul Kaegbein

    Index Scriptorium Estoniae

    Kaegbein, Paul

    2006-01-01

    Arvustus: Karin Hallas. Das Tallinner Mietshaus. Vom Historismus bis zum Jugendstil. In: Architektur und bildende Kunst im Baltikum um 1900. Frankfurt am Main, Berlin, Bern, Bruxelles, New York, Wien: Lang 1999. S. 173-192.

  19. mycobacterium tuberculosis genetic diversity and drug resistance ...

    African Journals Online (AJOL)

    East African Medical Journal Vol. 88 No. 12 December 2011. MYCOBACTERIUM TUBERCULOSIS GENETIC DIVERSITY AND DRUG RESISTANCE CONFERRING MUTATIONS. IN THE DEMOCRATIC REPUBLIC OF THE CONGO. L. Fenner, Institute of Social and Preventive Medicine, University of Bern, Switzerland, S.

  20. A majority in favour of the construction of further nuclear power stations

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    The results of an opinion poll of 5000 German-speaking persons in Bern Canton, Switzerland are summarised and commented on. 54% of those questioned expressed approval of further nuclear power station construction in Switzerland. (F.Q.)

  1. Genetics Home Reference: 15q13.3 microdeletion

    Science.gov (United States)

    ... GW, Spence JE, Amato S, Rousseau JA, Moghaddam B, Skinner C, Skinner SA, Bernes S, Armstrong N, Shinawi M, Stankiewicz P, ... Sharp AJ, Mefford HC, Li K, Baker C, Skinner C, Stevenson RE, Schroer RJ, Novara F, De ...

  2. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2003-01-01

    Heliplaatide "Higha Collection 3", "My Big Fat Greek Wedding", Apocalyptica "Reflections", The Raveonettes "Whip It On", Kaunimate Vennaskond "Kaunimad astad su elus", Led Zeppelin "Early Days& Latter Days", "The Heart And SAoul Of Bert Berns", Groove Armanda "Love Box" tutvustus

  3. 7TH International Workshop on Laser Physics (LPHYS󈨦) Berlin, Germany July 6-10, 1998 Program and Book of Abstracts: Volume 2.

    Science.gov (United States)

    1998-07-01

    Jang, L. Shah, G.M.Luntz, and M. Richardson CREOL , UCF., Orlando, Florida, USA Abstract: Yttrium calcium oxyborate (YCa4(B03)3) or YCOB) is a newly...observed the decrease in blood oxygen saturation during laser irradiation as a result of enhanced oxygen consumption during PDT and vessel...Berne, Murtenstr. 31, CH-3010 Bern Short- and long-term tissue effects, pressure and ablation efficiency of pig myocardium was evaluated after Er:YAG

  4. The presentation of energy topics at exhibitions

    International Nuclear Information System (INIS)

    Moergeli, H.P.

    1984-01-01

    The author examines the problems confronting an electricity supply company when trying to communicate its energy policy to the general public at exhibitions and fairs. The company has to convey a message of reliable power supplies, increasing demand, the advantages of nuclear energy, the safe storage of radioactive waste and the need for new generating plants. The author describes some of the displays being used to attract the public to the Bern Power Stations stand at the Bern Exhibition 1984. (R.S.)

  5. CODE rapid product series for the IGS

    OpenAIRE

    Dach, Rolf; Schaer, Stefan; Arnold, Daniel; Prange, Lars; Sidorov, Dmitry; Susnik, Andreja; Villiger, Arturo; Jäggi, Adrian

    2016-01-01

    CODE, the Center for Orbit Determination in Europe, is a joint venture of the following four institutions: Astronomical Institute, University of Bern (AIUB), Bern, Switzerland;Federal Office of Topography swisstopo, Wabern, Switzerland; Federal Agency of Cartography and Geodesy (BKG), Frankfurt a. M., Germany; Institut für Astronomische und Physikalische Geodäsie, Technische Universität München (IAPG, TUM), Munich, Germany. It acts as a global analysis center of the International GNSS Serv...

  6. Interprofessional team management in pediatric critical care: some challenges and possible solutions

    OpenAIRE

    Stocker, Martin; Pilgrim, Sina B; Burmester, Margarita; Allen, Meredith L; Gijselaers, Wim H

    2016-01-01

    Martin Stocker,1 Sina B Pilgrim,2 Margarita Burmester,3 Meredith L Allen,4 Wim H Gijselaers5 1Neonatal and Pediatric Intensive Care Unit, Children's Hospital Lucerne, Lucerne, 2Pediatric Intensive Care, University Children's Hospital Berne, Berne, Switzerland; 3Pediatric Intensive Care Unit, Royal Brompton Hospital, London, UK; 4Department of Pediatrics, The Royal Children's Hospital, Victoria, Australia; 5Educational Research and Development, School of Business and Ec...

  7. Effect of chum salmon egg lectin on tight junctions in Caco-2 cell monolayers.

    Science.gov (United States)

    Nemoto, Ryo; Yamamoto, Shintaro; Ogawa, Tomohisa; Naude, Ryno; Muramoto, Koji

    2015-05-05

    The effect of a chum salmon egg lectin (CSL3) on tight junction (TJ) of Caco-2 cell monolayers was investigated. The lectin opened TJ as indicated by the decrease of the transepithelial electrical resistance (TER) value and the increase of the permeation of lucifer yellow, which is transported via the TJ-mediated paracellular pathway. The effects of CSL3 were inhibited by the addition of 10 mM L-rhamnose or D-galactose which were specific sugars for CSL3. The lectin increased the intracellular Ca2+ of Caco-2 cell monolayers, that could be inhibited by the addition of L-rhamnose. The fluorescence immunostaining of β-actin in Caco-2 cell monolayers revealed that the cytoskeleton was changed by the CSL3 treatment, suggesting that CSL3 depolymerized β-actin to cause reversible TJ structural and functional disruption. Although Japanese jack bean lectin and wheat germ lectin showed similar effects in the decrease of the TER values and the increase of the intracellular Ca2+, they could not be inhibited by the same concentrations of simple sugars, such as D-glucose and N-acetyl-D-glucosamine.

  8. Effect of Chum Salmon Egg Lectin on Tight Junctions in Caco-2 Cell Monolayers

    Directory of Open Access Journals (Sweden)

    Ryo Nemoto

    2015-05-01

    Full Text Available The effect of a chum salmon egg lectin (CSL3 on tight junction (TJ of Caco-2 cell monolayers was investigated. The lectin opened TJ as indicated by the decrease of the transepithelial electrical resistance (TER value and the increase of the permeation of lucifer yellow, which is transported via the TJ-mediated paracellular pathway. The effects of CSL3 were inhibited by the addition of 10 mM L-rhamnose or D-galactose which were specific sugars for CSL3. The lectin increased the intracellular Ca2+ of Caco-2 cell monolayers, that could be inhibited by the addition of L-rhamnose. The fluorescence immunostaining of β-actin in Caco-2 cell monolayers revealed that the cytoskeleton was changed by the CSL3 treatment, suggesting that CSL3 depolymerized β-actin to cause reversible TJ structural and functional disruption. Although Japanese jack bean lectin and wheat germ lectin showed similar effects in the decrease of the TER values and the increase of the intracellular Ca2+, they could not be inhibited by the same concentrations of simple sugars, such as D-glucose and N-acetyl-D-glucosamine.

  9. Does childhood schooling affect old age memory or mental status? Using state schooling laws as natural experiments.

    Science.gov (United States)

    Glymour, M M; Kawachi, I; Jencks, C S; Berkman, L F

    2008-06-01

    The association between schooling and old age cognitive outcomes such as memory disorders is well documented but, because of the threat of reverse causation, controversy persists over whether education affects old age cognition. Changes in state compulsory schooling laws (CSL) are treated as natural experiments (instruments) for estimating the effect of education on memory and mental status among the elderly. Changes in CSL predict changes in average years of schooling completed by children who are affected by the new laws. These educational differences are presumably independent of innate individual characteristics such as IQ. CSL-induced changes in education were used to obtain instrumental variable (IV) estimates of education's effect on memory (n = 10,694) and mental status (n = 9751) for white, non-Hispanic US-born Health and Retirement Survey participants born between 1900 and 1947 who did not attend college. After adjustment for sex, birth year, state of birth and state characteristics, IV estimates of education's effect on memory were large and statistically significant. IV estimates for mental status had very wide confidence intervals, so it was not possible to draw meaningful conclusions about the effect of education on this outcome. Increases in mandatory schooling lead to improvements in performance on memory tests many decades after school completion. These analyses condition on individual states, so differences in memory outcomes associated with CSL changes cannot be attributed to differences between states. Although unmeasured state characteristics that changed contemporaneously with CSL might account for these results, unobserved genetic variation is unlikely to do so.

  10. Evolution of grain boundary character distributions in alloy 825 tubes during high temperature annealing: Is grain boundary engineering achieved through recrystallization or grain growth?

    International Nuclear Information System (INIS)

    Bai, Qin; Zhao, Qing; Xia, Shuang; Wang, Baoshun; Zhou, Bangxin; Su, Cheng

    2017-01-01

    Grain boundary engineering (GBE) of nickel-based alloy 825 tubes was carried out with different cold drawing deformations by using a draw-bench on a factory production line and subsequent annealing at various temperatures. The microstructure evolution of alloy 825 during thermal-mechanical processing (TMP) was characterized by means of the electron backscatter diffraction (EBSD) technique to study the TMP effects on the grain boundary network and the evolution of grain boundary character distributions during high temperature annealing. The results showed that the proportion of ∑ 3 n coincidence site lattice (CSL) boundaries of alloy 825 tubes could be increased to > 75% by the TMP of 5% cold drawing and subsequent annealing at 1050 °C for 10 min. The microstructures of the partially recrystallized samples and the fully recrystallized samples suggested that the proportion of low ∑ CSL grain boundaries depended on the annealing time. The frequency of low ∑ CSL grain boundaries increases rapidly with increasing annealing time associating with the formation of large-size highly-twinned grains-cluster microstructure during recrystallization. However, upon further increasing annealing time, the frequency of low ∑ CSL grain boundaries decreased markedly during grain growth. So it is concluded that grain boundary engineering is achieved through recrystallization rather than grain growth. - Highlights: •The grain boundary engineering (GBE) is applicable to 825 tubes. •GBE is achieved through recrystallization rather than grain growth. •The low ∑ CSL grain boundaries in 825 tubes can be increased to > 75%.

  11. Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody

    Directory of Open Access Journals (Sweden)

    Sophie E. Broughton

    2014-07-01

    Full Text Available Interleukin-3 (IL-3 is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Here, we report the crystal structure of the IL-3 receptor α chain (IL3Rα in complex with the anti-leukemia antibody CSL362 that reveals the N-terminal domain (NTD, a domain also present in the granulocyte-macrophage colony-stimulating factor (GM-CSF, IL-5, and IL-13 receptors, adopting unique “open” and classical “closed” conformations. Although extensive mutational analyses of the NTD epitope of CSL362 show minor overlap with the IL-3 binding site, CSL362 only inhibits IL-3 binding to the closed conformation, indicating alternative mechanisms for blocking IL-3 signaling. Significantly, whereas “open-like” IL3Rα mutants can simultaneously bind IL-3 and CSL362, CSL362 still prevents the assembly of a higher-order IL-3 receptor-signaling complex. The discovery of open forms of cytokine receptors provides the framework for development of potent antibodies that can achieve a “double hit” cytokine receptor blockade.

  12. On-site laboratory support of Oak Ridge National Laboratory environmental restoration field activities

    International Nuclear Information System (INIS)

    Burn, J.L.E.

    1995-07-01

    A remedial investigation/feasibility study has been undertaken at Oak Ridge National Laboratory (ORNL). Bechtel National, Inc. and partners CH2M Hill, Ogden Environmental and Energy Services, and PEER Consultants are contracted to Lockheed Martin Energy Systems, performing this work for ORNL's Environmental Restoration (ER) Program. An on-site Close Support Laboratory (CSL) established at the ER Field Operations Facility has evolved into a laboratory where quality analytical screening results can be provided rapidly (e.g., within 24 hours of sampling). CSL capabilities include three basic areas: radiochemistry, chromatography, and wet chemistry. Radiochemical analyses include gamma spectroscopy, tritium and carbon-14 screens using liquid scintillation analysis, and gross alpha and beta counting. Cerenkov counting and crown-ether-based separation are the two rapid methods used for radiostrontium determination in water samples. By extending count times where appropriate, method detection limits can match those achieved by off-site contract laboratories. Volatile organic compounds are detected by means of gas chromatography using either headspace or purge and trap sample introduction (based on EPA 601/602). Ionic content of water samples is determined using ion chromatography and alkalinity measurement. Ion chromatography is used to quantify both anions (based on EPA 300) and cations. Wet chemistry procedures performed at the CSL include alkalinity, pH (water and soil), soil resistivity, and dissolved/suspended solids. Besides environmental samples, the CSL routinely screens health and safety and waste management samples. The cost savings of the CSL are both direct and indirect

  13. On-site laboratory support of the Oak Ridge National Laboratory remedial investigation/feasibility study

    International Nuclear Information System (INIS)

    Burn, J.L.E.; Brooksbank, R.D.; Dillener, J.L.; Jeskie, T.R.

    1992-10-01

    In 1987, a remedial investigation/feasibility study (RI/FS) was begun at Oak Ridge National Laboratory (ORNL). ORNL had established a number of waste area groupings (WAGs), each of which was to be studied and characterized separately. Although the nature and extent of contamination at the WAGs vary widely, samples from each WAG might be radiologically and/or chemically contaminated. To comply with Department of Transportation (DOT) regulations regarding the shipment of hazardous and radioactive materials, all samples are screened for radioactivity before shipment to independent laboratories for further analysis. In 1989 a Close Support Laboratory (CSL) was established at the RI/FS Field Operations Facility at ORNL. The CSL began as a screening facility and has evolved into a laboratory where high-quality analytical results on a number of different parameters are usually available within 24 hours of sampling. CSL capabilities include three basic areas: radiochemistry, volatile organic analysis (VOA), and wet chemistry

  14. The Effects of Cassia Siamea Lam. Root Extract on the Corrosion and Kinetics of Corrosion Process of Copper in Alkaline Solutions

    Directory of Open Access Journals (Sweden)

    A. I Onen

    2011-01-01

    Full Text Available The effect of Cassia siamea lam. (CSL root extract as a corrosion inhibitor of copper in 0.50 M NaOH solutions was investigated using absorbance difference technique at 30 °C and 40 °C. CSL root extract inhibited the corrosion of copper in 0.50 M NaOH solutions and the inhibition efficiency (% IE increased to a maximum of 78.3±2.3% with increasing concentration of the extract but decreased with increasing temperature. The adsorption of CSL root extract on copper surface followed the Langmuir adsorption model with the average heat of adsorption, Qads and free energy of adsorption, ΔGads of -8.98 kJmol-1 and -8.70 kJmol-1 respectively. A kinetic treatment of the data revealed a first order kinetics with respect to copper in the presence and absence of the extract.

  15. Cost effective production of pullulan from agri-industrial residues using response surface methodology.

    Science.gov (United States)

    Mehta, Ananya; Prasad, G S; Choudhury, Anirban Roy

    2014-03-01

    Response surface methodology was used to develop an economically feasible process for the fermentative production of pullulan using agri-industrial residues, jaggery, de-oiled jatropha seed cake (DOJSC) and corn steep liquor (CSL), as sole media components. A second order polynomial model was obtained using central composite design to understand the effects of interactions among these substrates on pullulan biosynthesis. Results indicated that, lower concentrations of CSL and DOJSC and higher concentrations of jaggery favoured pullulan production. The optimal nutrient composition (18% jaggery, 3% DOJSC and 0.97% CSL) as suggested by the model resulted in production of 66.25 g/L pullulan with a productivity of 0.92 g/Lh. Analysis of raw material cost component for pullulan production suggested that sole utilization of agri-residues may lead to development of cost effective process for pullulan production. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. CsI electromagnetic calorimeter development for a low or medium energy e+e- collider

    International Nuclear Information System (INIS)

    King, M.E.

    1993-10-01

    Design considerations for an electromagnetic Csl calorimeter suitable for use at low and medium energy, high-luminosity e + e - storage rings are presented, together with results of a test of an array of Csl(Tl) crystals in an e - /π - beam (120 to 400 MeV) at TRIUMF. The crystal array used in the test was designed to explore longitudinal and transverse crystal segmentation, and a redundant wavelength-shifter and photodiode readout system. Energy resolution of (1.69 ± 0.08)%/√E and (1.83 ± 0.05)%/√E was obtained for two different crystal tower configurations. Position resolution of 6.5 (9.0) mm was obtained at 300 (120)MeV for four 4x4 cm 2 , 4 rl. Csl crystals

  17. Detecting continuous spontaneous localization with charged bodies in a Paul trap

    Science.gov (United States)

    Li, Ying; Steane, Andrew M.; Bedingham, Daniel; Briggs, G. Andrew D.

    2017-03-01

    Continuous spontaneous localization (CSL) is a model that captures the effects of a class of extensions to quantum theory which are expected to result from quantum gravity and is such that wave-function collapse is a physical process. The rate of such a process could be very much lower than the upper bounds set by searches to date and yet still modify greatly the interpretation of quantum mechanics and solve the quantum measurement problem. Consequently experiments are sought to explore this. We describe an experiment that has the potential to extend sensitivity to CSL by many orders of magnitude. The method is to detect heating of the motion of charged macroscopic objects confined in a Paul trap. We discuss the detection and the chief noise sources. We find that CSL with standard parameters could be observed using a vibration-isolated ion trap of size 1 cm at ultralow pressure with optical interferometric detection.

  18. A Materials Life Cycle Assessment of a Net-Zero Energy Building

    Directory of Open Access Journals (Sweden)

    Laura A. Schaefer

    2013-02-01

    Full Text Available This study analyzed the environmental impacts of the materials phase of a net-zero energy building. The Center for Sustainable Landscapes (CSL is a three-story, 24,350 square foot educational, research, and administrative office in Pittsburgh, PA, USA. This net-zero energy building is designed to meet Living Building Challenge criteria. The largest environmental impacts from the production of building materials is from concrete, structural steel, photovoltaic (PV panels, inverters, and gravel. Comparing the LCA results of the CSL to standard commercial structures reveals a 10% larger global warming potential and a nearly equal embodied energy per square feet, largely due to the CSL’s PV system. As a net-zero energy building, the environmental impacts associated with the use phase are expected to be very low relative to standard structures. Future studies will incorporate the construction and use phases of the CSL for a more comprehensive life cycle perspective.

  19. Latitudinal range influences the seasonal variation in the foraging behavior of marine top predators.

    Directory of Open Access Journals (Sweden)

    Stella Villegas-Amtmann

    Full Text Available Non-migratory resident species should be capable of modifying their foraging behavior to accommodate changes in prey abundance and availability associated with a changing environment. Populations that are better adapted to change will have higher foraging success and greater potential for survival in the face of climate change. We studied two species of resident central place foragers from temperate and equatorial regions with differing population trends and prey availability associated to season, the California sea lion (Zalophus californianus (CSL whose population is increasing and the endangered Galapagos sea lion (Zalophus wollebaeki (GSL whose population is declining. To determine their response to environmental change, we studied and compared their diving behavior using time-depth recorders and satellite location tags and their diet by measuring C and N isotope ratios during a warm and a cold season. Based on latitudinal differences in oceanographic productivity, we hypothesized that the seasonal variation in foraging behavior would differ for these two species. CSL exhibited greater seasonal variability in their foraging behavior as seen in changes to their diving behavior, foraging areas and diet between seasons. Conversely, GSL did not change their diving behavior between seasons, presenting three foraging strategies (shallow, deep and bottom divers during both. GSL exhibited greater dive and foraging effort than CSL. We suggest that during the warm and less productive season a greater range of foraging behaviors in CSL was associated with greater competition for prey, which relaxed during the cold season when resource availability was greater. GSL foraging specialization suggests that resources are limited throughout the year due to lower primary production and lower seasonal variation in productivity compared to CSL. These latitudinal differences influence their foraging success, pup survival and population growth reflected in

  20. Beneficial Effects of Reconstituted High-Density Lipoprotein (rHDL on Circulating CD34+ Cells in Patients after an Acute Coronary Syndrome.

    Directory of Open Access Journals (Sweden)

    Catherine Gebhard

    Full Text Available High-density lipoproteins (HDL favorably affect endothelial progenitor cells (EPC. Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS. This study investigates the short-term effects of reconstituted HDL (rHDL on circulating progenitor cells in patients with ACS.The study population consisted of 33 patients with recent ACS: 20 patients from the ERASE trial (randomized to receive 4 weekly intravenous infusions of CSL-111 40 mg/kg or placebo and 13 additional patients recruited as controls using the same enrolment criteria. Blood was collected from 16 rHDL (CSL-111-treated patients and 17 controls at baseline and at 6-7 weeks (i.e. 2-3 weeks after the fourth infusion of CSL-111 in ERASE. CD34+ and CD34+/kinase insert domain receptor (KDR+ progenitor cell counts were analyzed by flow cytometry. We found preserved CD34+ cell counts in CSL-111-treated subjects at follow-up (change of 1.6%, while the number of CD34+ cells was reduced (-32.9% in controls (p = 0.017 between groups. The level of circulating SDF-1 (stromal cell-derived factor-1, a chemokine involved in progenitor cell recruitment, increased significantly (change of 21.5% in controls, while it remained unchanged in CSL-111-treated patients (p = 0.031 between groups. In vitro exposure to CSL-111 of early EPC isolated from healthy volunteers significantly increased CD34+ cells, reduced early EPC apoptosis and enhanced their migration capacity towards SDF-1.The relative increase in circulating CD34+ cells and the low SDF-1 levels observed following rHDL infusions in ACS patients point towards a role of rHDL in cardiovascular repair mechanisms.

  1. Effect of different levels of corn steep liquor addition on fermentation characteristics and aerobic stability of fresh rice straw silage

    Directory of Open Access Journals (Sweden)

    Xinxin Li

    2016-12-01

    Full Text Available The object of this study was to determine the proper mixing ratio of fresh rice straw to corn steep liquor (CSL to obtain a high protein content silage feed. The following experimental silages were generated: the control (C1, composed of fresh rice straw without CSL additive, mixed with CSL in the ratios of 4:1 (C4, 3:1 (C3 and 2:1 (C2. Lactic acid bacteria (LAB inoculant was applied at the rate of 50 mL/kg (fresh basis of forage to achieve a final application rate of 1 × 106 cfu/g of fresh matter (FM. Duplicate silos for each treatment were opened after 0, 3, 7, 10, 20, 30, 45 and 60 d for microbiological and chemical analysis. The results showed that the addition of CSL significantly increased crude protein (CP contents, and decreased neutral detergent fiber (NDF and acid detergent fiber (ADF contents of treatments after 60 d of ensiling (P < 0.05. The lactic acid contents in C4 and C3 were significantly higher than that in C1 (P < 0.05. In summary, mixing fresh rice straw with CSL at addition levels of 4:1 (C4 and 3:1 (C3 can improve the fermentation quality and nutrient composition of fresh rice straw silage. However, a large proportion of CSL (C3 had a negative impact on the aerobic stability of fresh rice straw.

  2. Behaviour of radionuclides in biological and non-biological processes at very low concentrations

    International Nuclear Information System (INIS)

    Sinnaeve, J.; Frissel, M.J.; Klugt, N. van der; Geijn, S.C. van de.

    1980-01-01

    Four experiments using a 'biological exchange column', i.e. a cut papyrus stem were carried out. Prior to the passage of the labelled solution containing 250 μCi 137 Cs.l -1 , and 1 μCi 134 Cs.l -1 , the exchange sites of the stem were protonated. Two treatments were carried out, the first with 10 -4 M stable caesium in the labelled solution and the second with 10 -4 M potassium. After detection of the front of activity half way up the stem, 5 cm segments of the stem were cut and counted. (Auth.)

  3. Program scheme using common source lines in channel stacked NAND flash memory with layer selection by multilevel operation

    Science.gov (United States)

    Kim, Do-Bin; Kwon, Dae Woong; Kim, Seunghyun; Lee, Sang-Ho; Park, Byung-Gook

    2018-02-01

    To obtain high channel boosting potential and reduce a program disturbance in channel stacked NAND flash memory with layer selection by multilevel (LSM) operation, a new program scheme using boosted common source line (CSL) is proposed. The proposed scheme can be achieved by applying proper bias to each layer through its own CSL. Technology computer-aided design (TCAD) simulations are performed to verify the validity of the new method in LSM. Through TCAD simulation, it is revealed that the program disturbance characteristics is effectively improved by the proposed scheme.

  4. Impact of the European Russia drought in 2010 on the Caspian Sea level

    Directory of Open Access Journals (Sweden)

    K. Arpe

    2012-01-01

    Full Text Available The hydrological budgets of the Volga basin (VB and the Caspian Sea (CS have been analysed. The components of the water balance for the CS were calculated for the period 1993 to 2010 with emphasis on summer 2010 when a severe drought developed over European Russia.

    A drop in precipitation over the VB in July 2010 occurs simultaneously with a decrease in evaporation for the same area, an increase of evaporation over the CS itself and a drop of the Caspian Sea level (CSL. The drop in the precipitation over the VB cannot lead to an instantaneous drop of the CSL because the precipitated water needs some months to reach the CS. The delay is estimated here to be 1 to 3 months for excessive precipitation in summer, longer for deficient precipitation and for winter cases. However, the evaporation over the CS itself is considered to be responsible for a simultaneous drop of the CSL from July to September 2010. The impact on the CSL from the precipitation deficit over the VB occurs in the months following the drought. The water deficit from July to September 2010 calculated from the anomalous precipitation minus evaporation over the VB would decrease the CSL by 22 cm, of which only 2 cm had been observed until the end of September (observed Volga River discharge anomaly. So the remaining drop of 20 cm can be expected in the months to follow if no other anomalies happen. In previous studies the precipitation over the VB has been identified as the main cause for CSL changes, but here from a 10 cm drop from beginning of July to end of September, 6 cm can be directly assigned to the enhanced evaporation over the CS itself and 2 cm due to reduced precipitation over the CS.

    Further periods with strong changes of the CSL are also investigated, which provide some estimates concerning the accuracy of the analysis data. The investigation was possible due to the new ECMWF interim reanalysis data which are used to provide data also for sensitive

  5. The Bernese Emigration to the United States, 1870–1930: A Quantitative Analysis of Economic Factors

    Directory of Open Access Journals (Sweden)

    Simon Geissbühler

    1999-10-01

    Full Text Available The United States was the most important destination for emigrants from the Swiss canton of Bern during the period of mass emigration in the late 19th and the early 20th century. The present article looks at the economic factors leading to this mass emigration. Using bivariate correlations, this study demonstrates that quantitative analysis is a powerful tool in historical emigration research. The data underlines the two following theses. First, the better the economy in Bern, the lower the rate of emigration to the United States. Secondly, the better the economy in the United States, the higher the rate of emigration from Bern. Hence, both pull and push factors played an important role determining emigration from Bern to the United States. The most closely related to the rate of emigration were the independent variables emigration to the USA in year t-1, the investments in structural engineering in Bern, railroad construction in the USA and the number of Bernese on welfare. The results clearly show that Bernese emigration was primarily a socio-economic mass movement.

  6. Privilege, power, and public health programs: a student perspective on deconstructing institutional racism in community service learning.

    Science.gov (United States)

    Taboada, Arianna

    2011-01-01

    The Association of Schools of Public Health has identified "diversity and culture" as 1 of 7 crosscutting competencies that public health students are expected to achieve. This competency is traditionally incorporated into the curriculum through a community service-learning (CSL) component that aims to expose students to racial/ethnic health disparities. However, this model of CSL is problematic because although students are directly engaging with community members, it does not ensure long-term sustainable changes or benefits for the host community. Moreover, academic institutions have developed significant critiques of traditional CSL models where white middle-class students engage with low-income clients and communities of color, potentially reinforcing Eurocentric power and privilege. As such, public health programs require a shift in both pedagogy and curricula that more directly addresses underlying institutional racism in health disparities. Consistent with the principles of public health, a social justice framework is imperative in teaching cultural competency and should facilitate discussion of racial injustice and privilege in the students' own lives. This brief presents an autobiographical personal narrative of my experiences with CSL as a racial/ethnic minority student in a California graduate school of public health. Although autoethnography is inherently limited, this brief highlights my observations of the limitations of the service-learning model to adequately educate students on the intersection of racism and health outcomes. In addition, the brief includes suggestions for creating inclusive curricula that critically examine issues of privilege, oppression, and power dynamics related to race/ethnicity.

  7. Exploring the Reading-Writing Relationship in Young Chinese Language Learners' Sentence Writing

    Science.gov (United States)

    Wong, Yu Ka

    2018-01-01

    This study explored the concurrent and longitudinal relationships between reading and writing in young Chinese-as-a-second-language (CSL) learners' sentence writing, using structural equation modeling. The participants comprised 126 Hong Kong senior primary ethnic minority students, whose literacy skills were assessed at two time points over the…

  8. Annealing twins in a multifunctional beta Ti–Nb–Ta–Zr–O alloy

    Indian Academy of Sciences (India)

    The grain boundary character distribution and annealing twins in a multifunctional -type Ti–23Nb–0.7Ta–2Zr–O alloy having a stable bcc phase structure are investigated by electron backscattering diffraction (EBSD). The results show that the coincident site lattice (CSL) boundaries, including 3 and 11 twin boundaries ...

  9. Fulltext PDF

    Indian Academy of Sciences (India)

    in the nest algebras. Hopenwasser [4,5] generalized some of the above results to arbitrary. CSL algebras. On the other hand, Katsoulis, Moore and Trent [6] generalized Lance's theorem to multi-vectors and Anoussis [1] arrived at the same result independently. In this paper, we mainly consider the compact interpolation ...

  10. Jordan (α,β-Derivations on Operator Algebras

    Directory of Open Access Journals (Sweden)

    Quanyuan Chen

    2017-01-01

    Full Text Available Let A be a CSL subalgebra of a von Neumann algebra acting on a Hilbert space H. It is shown that any Jordan (α,β-derivation on A is an (α,β-derivation, where α,β are any automorphisms on A. Moreover, the nth power (α,β-maps on A are investigated.

  11. The United States Army Logistics Center Historical Summary (RCS-HIS-6 (R2)), 1 October 1978 to 30 September 1979.

    Science.gov (United States)

    1980-09-18

    instrumentation. A second meeting was held at CSL specifically on Hybrid Collective Protection Equipment ( HCPE ). Three systems--XMi Tank, ROLAND and Forward...HAAPS High Altitude Airdrop Resupply System HCPE Hybrid Collective Protection Equipment HET Heavy Equipment Transporter HEMTT Heavy Expanded Mobility

  12. Opinions of Pre-Service Teachers towards Community Service ...

    African Journals Online (AJOL)

    This study examines the opinions of 41 teacher candidates taking a community service learning (CSL) course. The implementation of this course and its contributions to participants' personal, social and academic development were examined using qualitative methods. Data was collected using semi-structured interview ...

  13. Students‟ reflections on the attainment of competencies in a ...

    African Journals Online (AJOL)

    Community service-learning (CSL) is advocated as a pedagogical tool to impart knowledge, attitudes and skills to students. This study aimed at determining whether community service-learning was a suitable method of instruction for recreation students to acquire the competencies needed in the field. Competencies ...

  14. Social aspects of conservation in the Eastern Arc Mountain forests ...

    African Journals Online (AJOL)

    Social aspects of conservation in the Eastern Arc Mountain forests. CSL Chachage. Abstract. Journal of East African Natural History Vol. 87 (1&2) 1998: 253-263. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  15. Relationships between Reading Comprehension and Its Components in Young Chinese-as-a-Second-Language Learners

    Science.gov (United States)

    Wong, Yu Ka

    2017-01-01

    Based on the Simple View of Reading model, this study examines the relationships among Chinese reading comprehension and its two componential processes, Chinese character reading and listening comprehension, in young learners of Chinese as a second language (CSL) using a longitudinal design. Using relevant measures, a sample of 142 senior primary…

  16. Anomalous electrodynamics of neutral pion matter in strong magnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Brauner, Tomáš [Department of Mathematics and Natural Sciences, University of Stavanger,N-4036 Stavanger (Norway); Kadam, Saurabh V. [Indian Institute of Science Education and Research (IISER),Pune 411008 (India)

    2017-03-03

    The ground state of quantum chromodynamics in sufficiently strong external magnetic fields and at moderate baryon chemical potential is a chiral soliton lattice (CSL) of neutral pions https://arxiv.org/abs/1609.05213. We investigate the interplay between the CSL structure and dynamical electromagnetic fields. Our main result is that in presence of the CSL background, the two physical photon polarizations and the neutral pion mix, giving rise to two gapped excitations and one gapless mode with a nonrelativistic dispersion relation. The nature of this mode depends on the direction of its propagation, interpolating between a circularly polarized electromagnetic wave https://www.doi.org/10.1103/PhysRevD.93.085036 and a neutral pion surface wave, which in turn arises from the spontaneously broken translation invariance. Quite remarkably, there is a neutral-pion-like mode that remains gapped even in the chiral limit, in seeming contradiction to the Goldstone theorem. Finally, we have a first look at the effect of thermal fluctuations of the CSL, showing that even the soft nonrelativistic excitation does not lead to the Landau-Peierls instability. However, it leads to an anomalous contribution to pressure that scales with temperature and magnetic field as T{sup 5/2}(B/f{sub π}){sup 3/2}.

  17. Understanding Learning and Learning Design in MOOCs: A Measurement-Based Interpretation

    Science.gov (United States)

    Milligan, Sandra; Griffin, Patrick

    2016-01-01

    The paper describes empirical investigations of how participants in a MOOC learn, and the implications for MOOC design. A learner capability to generate higher order learning in MOOCs--called crowd-sourced learning (C-SL) capability--was defined from learning science literature. The capability comprised a complex yet interrelated array of…

  18. Model Checking Structured Infinite Markov Chains

    NARCIS (Netherlands)

    Remke, Anne Katharina Ingrid

    2008-01-01

    In the past probabilistic model checking hast mostly been restricted to finite state models. This thesis explores the possibilities of model checking with continuous stochastic logic (CSL) on infinite-state Markov chains. We present an in-depth treatment of model checking algorithms for two special

  19. Chinese Sign Language Recognition Based on an Optimized Tree-Structure Framework.

    Science.gov (United States)

    Yang, Xidong; Chen, Xiang; Cao, Xiang; Wei, Shengjing; Zhang, Xu

    2017-07-01

    Chinese Sign Language (CSL) subword recognition based on surface electromyography (sEMG), accelerometer (ACC), and gyroscope (GYRO) sensors was explored in this paper. In order to fuse effectively the information of these three kinds of sensors, the classification abilities of sEMG, ACC, GYRO, and their combinations in three common sign components (one or two handed, hand orientation, and hand amplitude) were evaluated first and then an optimized tree-structure classification framework was proposed for CSL subword recognition. Eight subjects participated in this study and recognition experiments under different testing conditions were implemented on a target set consisting of 150 CSL subwords. The proposed optimized tree-structure classification framework based on sEMG, ACC, and GYRO obtained the best performance among seven different testing conditions with single sensor, paired-sensor fusion, and three-sensor fusion, and the overall recognition accuracies of 94.31% and 87.02% were obtained for 150 CSL subwords in a user-specific test and user-independent test, respectively. Our study could lay a basis for the implementation of large-vocabulary sign language recognition system based on sEMG, ACC, and GYRO sensors.

  20. The Influence of Anode Inner Contour on Atmospheric DC Plasma Spraying Process

    Directory of Open Access Journals (Sweden)

    Kui Wen

    2017-01-01

    Full Text Available In thermal plasma spraying process, anode nozzle is one of the most important components of plasma torch. Its inner contour controls the characteristics of plasma arc/jet, determining the motion and heating behaviors of the in-flight particles and hence influencing the coating quality. In this study, the effects of anode inner contour, standard cylindrical nozzle, and cone-shaped Laval nozzle with conical shape diverging exit (CSL nozzle on the arc voltage, net power, thermal efficiency, plasma jet characteristics, in-flight particle behaviors, and coating properties have been systematically investigated under atmospheric plasma spraying conditions. The results show that the cylindrical nozzle has a higher arc voltage, net power, and thermal efficiency, as well as the higher plasma temperature and velocity at the torch exit, while the CSL nozzle has a higher measured temperature of plasma jet. The variation trends of the plasma jet characteristics for the two nozzles are comparable under various spraying parameters. The in-flight particle with smaller velocity of CSL nozzle has a higher measured temperature and melting fraction. As a result, the coating density and adhesive strength of CSL nozzle are lower than those of cylindrical nozzle, but the deposition efficiency is greatly improved.

  1. Corn steep liquor as a nutrition adjunct for the production of Aspergillus niger lipase and hydrolysis of oils thereof.

    Science.gov (United States)

    Edwinoliver, N G; Thirunavukarasu, K; Purushothaman, S; Rose, C; Gowthaman, M K; Kamini, N R

    2009-11-25

    Corn steep liquor (CSL) has been used as a nutrition adjunct for the production of an extracellular lipase from Aspergillus niger, which has immense importance as an additive in laundry detergent formulations. A five-level four-factorial central composite design was chosen to determine the optimal medium components with four critical variables, namely, CSL, NH4H2PO4, Na2HPO4, and sesame oil, that were found to be influential for lipase production by the classical one-factor-at-a-time method. The model suggested that all of the factors chosen had a significant impact on lipase production, and the optimum values of the influential parameters were CSL, 2.0%, w/v; NH4H2PO4, 0.05%, w/v; Na2HPO4, 0.75%, w/v; and sesame oil, 2.0%, w/v, with an activity of 26.7 U/mL at 48 h and 30 degrees C, which was 2.16-fold higher than the initial activity (12 U/mL) obtained by the conventional one-factor-at-a-time method. Furthermore, the enzyme has good potential for the hydrolysis of vegetable oils and fish oils, and a hydrolytic ratio of 88.73% was obtained with palm oil at 48 h. The utilization of CSL and sesame oil for lipase production from A. niger makes the process green, because both are renewable substrates and economically viable at an industrial scale.

  2. The manufacturing, assembly and acceptance testing of the breadboard Cryogenic Optical Delay Line for DARWIN

    NARCIS (Netherlands)

    Dool, T.C. van den; Kamphues, F.G.; Gielesen, W.L.M.; Dorrepaal, M.; Doelman, N.J.; Loix, N.; Verschueren, J.P.; Kooijman, P.P.; Visser, M.; Velsink, G.; Fleury, K.

    2005-01-01

    TNO, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has developed a compact breadboard cryogenic Optical Delay Line for use in future space interferometry missions. The work is performed under ESA contract in preparation for the DARWIN mission. The breadboard delay line is

  3. Polysaccharide of caper (Capparis spinosa L.) Leaf: Extraction optimization, antioxidant potential and antimicrobial activity.

    Science.gov (United States)

    Mazarei, Farzad; Jooyandeh, Hossein; Noshad, Mohammad; Hojjati, Mohammad

    2017-02-01

    Three-variable-three-level Box-Behnken design-response surface methodology (BBD-RSM) based on the single-factor experiments was used to optimize the extracting parameters of crude polysaccharides (CPSs) from the Capparis spinosa leaves (CSL) including extraction time (ETi, 60-120min), extraction temperature (ETe, 60-80°C), and the water/solid ratio (W/S, 6-16). The optimal process conditions in order to the highest yield (6.73%) of CSL-CPSs were 119.8min ETi, 72.84°C ETe, and 15.97:1W/S.Structure of polysaccharide extracted at the optimal operating point were identified by Fourier transform-infrared spectroscopy (FT-IR). CSL-CPSs (50-300μg/L) revealed significantly scavenging activities against 2,2-diphenyl-1-picrylhydrazyl (DPPH)and OH free-radicals in vitro. A much more antimicrobial activity using this polysaccharide against Gram-negative bacteria (Escherichia coli, Shigella dysenteriaeandSalmonella typhi) was found than Gram-positive bacteria (Bacillus panis and Staphylococcus aureus). CSL-CPSs can thus be used as anexcellent antioxidant and antimicrobial ingredient in food and medicinal preparations. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Strategies for reducing supplemental medium cost in bioethanol production from waste house wood hydrolysate by ethanologenic Escherichia coli: inoculum size increase and coculture with Saccharomyces cerevisiae.

    Science.gov (United States)

    Okuda, Naoyuki; Ninomiya, Kazuaki; Katakura, Yoshio; Shioya, Suteaki

    2008-02-01

    In this paper, we report a simultaneous realization of both efficient ethanol production and saving medium nutrient (corn steep liquor [CSL]) during bioethanol fermentation of overliming-treated hydrolysate of waste house wood (WHW) using ethanologenic Escherichia coli KO11. In cultivation using WHW hydrolysate supplemented with 4% (v/v) CSL and 0.2 g-dry cell weight (DCW)/l E. coli KO11 cells, the overall ethanol yield reached 84% of the theoretical value at 61 h. When we conducted the cultivation with 1% CSL to reduce the supplemental medium cost, the overall ethanol yield remained in the range of 66-72% even at 90 h. We proposed two alternative methods for increasing the overall yield even with 1% CSL. The first method involved increasing the inoculum size of E. coli KO11 up to 0.8 g-DCW/l, where 83% of the overall yield was attained at 60 h of cultivation. The second method involved the coculture of 0.2 g-DCW/l E. coli KO11 together with 0.02 g-DCW/l of Saccharomyces cerevisiae TJ1, and the overall yield reached 81% at 47 h of cultivation.

  5. Third-year medical students' and clinical teachers' perceptions of ...

    African Journals Online (AJOL)

    Background. Clinical skills training in the clinical skills laboratory (CSL) environment forms an important part of the undergraduate medical curriculum. These skills are better demonstrated than described. A lack of direct observation and feedback given to medical students performing these skills has been reported. Without ...

  6. Studies on the antimicrobial effect of corn steep liquor on some ...

    African Journals Online (AJOL)

    ROFIAT

    2014-01-08

    Jan 8, 2014 ... The antimicrobial effect of Corn Steep Liquor (CSL) was investigated over a five day period. The pH and titrable acidity of the liquor were determined, while the antimicrobial effect on some diarrhoea causing organisms such as Escherichia coli, Salmonella enteriditis, Staphylococcus aureus and Vibrio.

  7. D-glucose:oxygen-1-oxidoreductase by using Aspergillus niger UV ...

    African Journals Online (AJOL)

    Jane

    2011-10-24

    Oct 24, 2011 ... type Aspergillus niger was subjected to ultraviolet radiation for enhanced production of glucose oxidase. It was found that ... Optimum production of glucose oxidase from A. niger UV-180-C was carried out by using CSL. (2%), fermentation period .... using Whatman filter paper No. 1 and centrifuged for 15 ...

  8. Reduction in Rotavirus-associated Acute Gastroenteritis Following Introduction of Rotavirus Vaccine Into Australia's National Childhood Vaccine Schedule

    NARCIS (Netherlands)

    Buttery, Jim P.; Lambert, Stephen B.; Grimwood, Keith; Nissen, Michael D.; Field, Emma J.; Macartney, Kristine K.; Akikusa, Jonathan D.; Kelly, Julian J.; Kirkwood, Carl D.

    Introduction: Rotavirus vaccines were introduced into the funded Australian National Immunization Program (NIP) in July 2007. Due to purchasing arrangements, individual states and territories chose either a 2-dose RV1 (Rotarix, GSK) regimen or 3-dose RV5 (Rotateq, Merck/CSL) regimen. This allowed

  9. The Effects of an Alternative Spring Break Program on Student Development

    Science.gov (United States)

    Beatty, Stephanie Hayne; Meadows, Ken N.; SwamiNathan, Richard; Mulvihill, Catherine

    2016-01-01

    This study examined the potential impact of a week-long cocurricular community service-learning (CSL) program on undergraduate students' psychosocial development. Participants in the Alternative Spring Break program and a matched control group completed surveys assessing a number of psychosocial variables immediately before and after the program,…

  10. Statistical optimization of medium composition for bacterial cellulose production by Gluconacetobacter hansenii UAC09 using coffee cherry husk extract--an agro-industry waste.

    Science.gov (United States)

    Rani, Mahadevaswamy Usha; Rastogi, Navin K; Appaiah, K A Anu

    2011-07-01

    During the production of grape wine, the formation of thick leathery pellicle/bacterial cellulose (BC) at the airliquid interface was due to the bacterium, which was isolated and identified as Gluconacetobacter hansenii UAC09. Cultural conditions for bacterial cellulose production from G. hansenii UAC09 were optimized by central composite rotatable experimental design. To economize the BC production, coffee cherry husk (CCH) extract and corn steep liquor (CSL) were used as less expensive sources of carbon and nitrogen, respectively. CCH and CSL are byproducts from the coffee processing and starch processing industry, respectively. The interactions between pH (4.5- 8.5), CSL (2-10%), alcohol (0.5-2%), acetic acid (0.5- 2%), and water dilution rate to CCH ratio (1:1 to 1:5) were studied using response surface methodology. The optimum conditions for maximum BC production were pH (6.64), CSL (10%), alcohol (0.5%), acetic acid (1.13%), and water to CCH ratio (1:1). After 2 weeks of fermentation, the amount of BC produced was 6.24 g/l. This yield was comparable to the predicted value of 6.09 g/l. This is the first report on the optimization of the fermentation medium by RSM using CCH extract as the carbon source for BC production by G. hansenii UAC09.

  11. Investigating Mobile-Assisted Oral Feedback in Teaching Chinese as a Second Language

    Science.gov (United States)

    Xu, Qi; Peng, Hongying

    2017-01-01

    This article reports on an exploratory study investigating mobile-assisted oral feedback in teaching Chinese as a second language (CSL). It is aimed at exploring the characteristics of mobile-assisted feedback on oral production with the smartphone social communication app WeChat as a case in point and examining learners' perceptions of…

  12. A trace-based model for multiparty contracts

    DEFF Research Database (Denmark)

    Hvitved, Tom; Klaedtke, Felix; Zălinescu, Eugen

    2012-01-01

    the operational semantics we derive a run-time monitor. CSL overcomes limitations of previously proposed formalisms for specifying contracts by supporting: (history sensitive and conditional) commitments, parametrised contract templates, relative and absolute temporal constraints, potentially in¿nite contracts...

  13. The development of a cryogenic optical delay line for DARWIN

    NARCIS (Netherlands)

    Dool, T.C. van den; Kamphues, F.G.

    2005-01-01

    TNO, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line for use in future space interferometry missions. The work is performed under ESA contract in preparation for the DARWIN mission. The breadboard (BB) delay line is

  14. A low-cost Lactobacillus salivarius L29 growth medium containing ...

    African Journals Online (AJOL)

    akpobome uruemuesiri

    2013-04-17

    Apr 17, 2013 ... The aim of the present work was to formulate a Lactobacillus salivarius L29 industrial fermentation medium. High cell numbers and good levels of lactic acid by a L. salivarius L29 were obtained after shake flask fermentation using molasses as the sole carbon source and corn steep liquor (CSL. (industrial ...

  15. Is the breakthrough of light electric-powered vehicles imminent?; Leicht-Elektromobile vor dem Durchbruch?

    Energy Technology Data Exchange (ETDEWEB)

    Stricker, B.

    1995-09-01

    Light electric-powered vehicles still exist in the shadow beside gasoline-operated automobiles. One reason for this lies in the economic recession, another in the marketing strategy for the Swatch vehicle due to be put on the market shortly. The report gives an overview of the light vehicles shown this year at Berne`s solar vehicle exhibition. TWIKE, an innovative, energy-efficient tricycle, is particularly pointed out. (BWI) [Deutsch] Leicht-Elektromobile fristen leider immer noch ein Schattendasein neben den benzinbetriebenen Automobilen. Der Grund dafuer ist neben der rezessiven Wirtschaftstendenz auch in der Marketing-Strategie fuer das zu erwartende Swatch-Mobil zu sehen. Der vorliegende Beitrag gibt einen Ueberblick ueber die auf dem diesjaehrigen Solarsalon in Bern gezeigten Leichtmobile. Besonders hervorgehoben wird dabei TWIKE, ein innovatives, energieeffizientes Dreirad. (BWI)

  16. Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.

    Science.gov (United States)

    Tabaja, Nassif; Yuan, Zhenyu; Oswald, Franz; Kovall, Rhett A

    2017-06-23

    The Notch pathway is a cell-to-cell signaling mechanism that is essential for tissue development and maintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects, and cardiovascular diseases. Notch signaling activates the expression of target genes, which are regulated by the transcription factor CSL (CBF1/RBP-J, Su(H), Lag-1). CSL interacts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor and activator, respectively. Although Notch activation complexes are relatively well understood at the structural level, less is known about how CSL interacts with corepressors. Recently, a new RBP-J (mammalian CSL ortholog)-interacting protein termed RITA has been identified and shown to export RBP-J out of the nucleus, thereby leading to the down-regulation of Notch target gene expression. However, the molecular details of RBP-J/RITA interactions are unclear. Here, using a combination of biochemical/cellular, structural, and biophysical techniques, we demonstrate that endogenous RBP-J and RITA proteins interact in cells, map the binding regions necessary for RBP-J·RITA complex formation, and determine the X-ray structure of the RBP-J·RITA complex bound to DNA. To validate the structure and glean more insights into function, we tested structure-based RBP-J and RITA mutants with biochemical/cellular assays and isothermal titration calorimetry. Whereas our structural and biophysical studies demonstrate that RITA binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch, our biochemical and cellular assays suggest that RITA interacts with additional regions in RBP-J. Taken together, these results provide molecular insights into the mechanism of RITA-mediated regulation of Notch signaling, contributing to our understanding of how CSL functions as a transcriptional repressor of Notch target genes. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  17. Towards building a prototype spin-logic device

    Science.gov (United States)

    Penumatcha, Ashish Verma

    Since the late 1980s, several key discoveries, such as Giant and Tunneling Magne- toresistance, and advances in magnetic materials have paved the way for exponentially higher bit-densities in magnetic storage. In particular, the discovery of Spin-Transfer Torque (STT) has allowed information to be written to individual magnets using spin-currents. This has replaced the more traditional Oersted-field control used in field-MRAMs and allowed further scaling of magnetic-memories. A less obvious con- sequence of STT is that it has made possible a logic-technology based on magnets controlled by spin-polarized currents. Charge-coupled Spin Logic (CSL) is one such device proposal that couples a giant spin Hall effect(GSHE) write-unit with a Mag- netic Tunnel Junction read-unit. Several theoretical reports have demonstrated that a CSL-style device can function as a fundamental building block for neuromorphic computing by harnessing the intrinsic properties of magnets. This thesis describes the working of a CSL device. Experimental progress towards building the individual components of CSL and also our efforts to integrate these components into a CSL prototype will be presented. In addition to the integration effort, this work also explores spin-injection from a GSHE metal to a nanoscale magnet through an intermediate non-magnetic metal. Our results indicate that with the right choice of intermediate layers, the spin-angular mo- mentum absorbed by the magnet can be increased without engineering the intrinsic spin Hall angle of the GSHE metal. Finally, this work also proposes a Schottky-barrier model to describe the current flow through low-dimensional semiconductors and uses it to extract the band gap of black-phosphorus thin-films in an attempt to characterize novel 2D-materials.

  18. Long-term oxygen therapy in COPD patients: population-based cohort study on mortality

    Directory of Open Access Journals (Sweden)

    Pavlov N

    2018-03-01

    Full Text Available Nikolay Pavlov,1 Alan Gary Haynes,2,3 Armin Stucki,4 Peter Jüni,5 Sebastian Robert Ott1 1Department of Pulmonary Medicine, University Hospital (Inselspital, University of Bern, Bern, Switzerland; 2CTU Bern, University of Bern, Bern, Switzerland; 3Institute of Social and Preventive Medicine (ISPM, University of Bern, Bern, Switzerland; 4Department of Internal Medicine, Spital Thun, Thun, Switzerland; 5Applied Health Research Centre, Li Ka Shing Knowledge Institute of St Michael’s Hospital, Department of Medicine, University of Toronto, Toronto, ON, Canada Purpose: Chronic obstructive pulmonary disease (COPD is the fourth leading cause of death worldwide and is associated with a growing and substantial socioeconomic burden. Long-term oxygen therapy (LTOT, recommended by current treatment guidelines for COPD patients with severe chronic hypoxemia, has shown to reduce mortality in this population. The aim of our study was to assess the standardized mortality ratios of incident and prevalent LTOT users and to identify predictors of mortality. Patients and methods: We conducted a 2-year follow-up population-based cohort study comprising all COPD patients receiving LTOT in the canton of Bern, Switzerland. Comparing age- and sex-adjusted standardized mortality ratios, we examined associations between all-cause mortality and patient characteristics at baseline. To avoid immortal time bias, data for incident (receiving LTOT <6 months and prevalent users were analyzed separately. Results: At baseline, 475 patients (20% incident users, n=93 were receiving LTOT because of COPD (48/100,000 inhabitants. Mortality of incident and prevalent LTOT users was 41% versus 27%, respectively, p<0.007, and standardized mortality ratios were 8.02 (95% CI: 5.64–11.41 versus 5.90 (95% CI: 4.79–7.25, respectively. Type 2 respiratory failure was associated with higher standardized mortality ratios among incident LTOT users (60.57, 95% CI: 11.82–310.45, p=0

  19. The Swiss national network for isotopes in the hydrological cycle

    International Nuclear Information System (INIS)

    Schotterer, U.

    1998-01-01

    The network is based on the long-term stations of the Climate and Environmental Physics Group and includes 11 precipitation, 6 river and 3 ground water stations. For the isotope measurements the Universities of Bern (Climate and Environmental Physics Group, tritium and oxygen-18) and Lausanne (Institute for Mineralogy and Petrography, deuterium) are contracted on a year to year basis. Sampling instructions, collection and shipment of samples are within the responsibility of the Bern group. The sampling apart from monthly composites of precipitation includes also samples from surface and ground water. The isotope data are available by contacting the Swiss Hydrological and Geological Survey directly

  20. FEPSAC newsletter (May 2016)

    OpenAIRE

    Sanchez, Xavier; Fritsch, Julian

    2016-01-01

    Welcome to this issue of the FEPSAC Newsletter – Fédération Européenne de Psychologie des Sport et des Activités Corporelles (European Federation of Sport Psychology).\\ud \\ud FEPSAC 2015 Awards\\ud During the 14th European Congress of Sport Psychology held in Bern, Switzerland (14–19 July 2015), Professor Roland Seiler, University of Bern, was bestowed the statutory Honorary Membership during the General Assembly. The Honorary Membership is a major honor, awarded for life and aimed at acknowle...

  1. Determination of the accumulator plants in Kucukcekmece Lake ...

    African Journals Online (AJOL)

    Yomi

    2010-09-27

    Sep 27, 2010 ... to increase the amount and quality of agricultural production, discharge of soil and liquid wastes, performing wastewater sludge .... The industry and residence activities around the lake grow very rapidly, especially the ..... CH-3048, Worblaufen-Bern Switzerland. Moauro A, Triola L, Avino P, Ferrandi L ...

  2. Download this PDF file

    African Journals Online (AJOL)

    NWUuser

    Property Law, University of Pretoria; Former Deputy President of the Supreme Court of Appeal of .... concentrate on them. The Berne Convention for the Protection of Literary and Artistic Works of 1886, which applies to literary and artistic works in the literary, .... Com Plc v Rodney Fitch & Company Ltd,23 a judgment of.

  3. Engineering a wild fast-growing Mycoplasma bacterium to generate ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-01-12

    Jan 12, 2018 ... This project is a collaboration between The University of Bern in Switzerland and the Institut national de la recherche agronomique (INRA)-University of Bordeaux. The team will also collaborate with scientists from the J. Craig Venter Institute in the USA. Duration: 24 months; Budget: CA$1.4 million ...

  4. Competition between Public Supervision and Professional Management: An Ethnographic Study of School Governance Reforms in Switzerland

    Science.gov (United States)

    Hangartner, Judith; Svaton, Carla Jana

    2014-01-01

    This article discusses insights from an ethnographic study of local governance practices in the Canton of Bern, Switzerland, under changing policy conditions. Recent reforms introduced and strengthened the position of head teachers, enhanced the responsibility of the municipalities and introduced new quality management procedures in local…

  5. Development of a novel vaccine for contagious caprine ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This project will use cutting-edge synthetic biology tools to construct a vaccine for CCPP that will grow efficiently, express protective Mccp antigens, and be used either as a live or inactivated vaccine. This 24-month project is a collaboration between the University of Bern in Switzerland, the Institut national de la recherche ...

  6. 76 FR 71308 - Codex Alimentarius Commission: Meeting of the Ad Hoc Intergovernmental Codex Task Force on Animal...

    Science.gov (United States)

    2011-11-17

    ... Alimentarius Commission (Codex), which will be held in Berne Switzerland, February 20-24, 2012. The Under... meat, milk and eggs). The AFTF is hosted by Switzerland. Issues to be Discussed at the Public Meeting... communicated via Listserv, a free electronic mail subscription service for industry, trade groups, consumer...

  7. 78 FR 1196 - Codex Alimentarius Commission: Meeting of the Ad Hoc Codex Intergovernmental Task Force on Animal...

    Science.gov (United States)

    2013-01-08

    ... Berne, Switzerland, February 4-8, 2013. The Under Secretary for Food Safety and the Center for... hosted by Switzerland. Issues to be Discussed at the Public Meeting The following items on the agenda for... subscription service for industry, trade groups, consumer interest groups, health professionals, and other...

  8. Comparison of continuous in situ CO2 observations at Jungfraujoch using two different measurement techniques

    NARCIS (Netherlands)

    Schibig, M.F.; Steinbacher, M.; Buchmann, B.; Laan-Luijkx, van der I.T.; Laan, van der S.; Ranjan, S.; Leuenberger, M.C.

    2015-01-01

    Since 2004, atmospheric carbon dioxide (CO2) is being measured at the High Altitude Research Station Jungfraujoch by the division of Climate and Environmental Physics at the University of Bern (KUP) using a nondispersive infrared gas analyzer (NDIR) in combination with a paramagnetic O2 analyzer. In

  9. Development of a novel vaccine for contagious caprine ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... grow efficiently, express protective Mccp antigens, and be used either as a live or inactivated vaccine. This 24-month project is a collaboration between the University of Bern in Switzerland, the Institut national de la recherche agronomique at the University of Bordeaux, France, and the J. Craig Venter Institute in the USA.

  10. Clipboard

    Indian Academy of Sciences (India)

    SEARCHU

    the limits of animal psychology. Rutte and Taborsky were least likely to have been influenced by any such. “superiority complex”. Along with Martin Brinkhof of the Department of Social and Preventive Medicine in the University of Berne, Rutte and Taborsky have been thinking deeply about another remarkable phenomenon ...

  11. From Autonomy to Quality Management: NPM Impacts on School Governance in Switzerland

    Science.gov (United States)

    Hangartner, Judith; Svaton, Carla Jana

    2013-01-01

    This article reviews the impact of discourses on "New Public Management" (NPM) on compulsory schooling in Switzerland during the last two decades and traces its implementation in the Canton of Bern. The analysis suggests that while NPM reformers initially promoted increased school autonomy, the introduction of market elements and school…

  12. Untitled

    Indian Academy of Sciences (India)

    Rev. 135A 1691. Berne B J and Pecora R 1976 Dynamic light scattering (New York : John Wiley). Celasco M, Fiorillo F and Mazzetti P 1976 Phys. Rey. Lett. 36 38. Harrison W A 1966 Pseudopotentials in the theory of metals (Reading, Mass.: Benjamin). Van Hove L. 1954 Phys. Rev. 95 249. Vineyard G H 1958 Phys. Rev.

  13. compounds: Structure–antitumor activity considerations

    Indian Academy of Sciences (India)

    Administrator

    human colon, gastric and prostate carcinomas. New strategies in ligand design, coordination chemistry with coinage metals (Au and Ag) and structure-biological activity considerations are presented. References. 1. Katti K V, Gali H, Smith C J and Berning D E 1999 Acc. Chem. Res. 32 9. 2. Gali H, Karra S R, Reddy V S and ...

  14. Characterizations of Nanofluid Heat Transfer Enhancements

    Science.gov (United States)

    2013-09-06

    characterization methodologies in environmental risk assessment of engineered nanoparticles. Ecotoxicology , 2008. 17(5): p. 344-361. 40 33. Berne, B.J. and R...74. Am Ende, D.J. Chemical Engineering in the Pharmaceutical Industry R & D to Manufacturing. 2011; Available from: http://public.eblib.com

  15. An Interpretative Phenomenological Analysis of Schema Modes in a ...

    African Journals Online (AJOL)

    cognitive behavioural therapy (CBT) and existential therapy (Yalom, 1989). However, unlike the “Adult” in. Transactional Analysis (TA), which Berne (1961) defined as a rational problem-solver, the HA is conceptualized as what Carl Rogers (1967) called a “fully functioning person”, with the capacity not only for rationality but.

  16. Perché è necessario capire il web

    CERN Multimedia

    Rosenthal, Edward C

    2007-01-01

    The birth of the cobweb of contents, the web 2.0, Wikipedia, the global collaboration, i blog, the net neutrality, the digital liberty and the future of the net: interview with Robert Cailliau, inventor of the WWW with Tim Bernes-Lee. (2 pages)

  17. Download this PDF file

    African Journals Online (AJOL)

    Carlo siriiulations of molecules placed at the site of a simple cubic lattice and interacting via the modified Gay-Berne ... Crystalline state has been made by simulating a range of simplified potential models such as lattice models [7-11]. hard .... where e' and ey are given by equations (7) and (9), respectively. The GB potential ...

  18. Academic Training: Climate change and challenges for the environment / POSTPONED!!!

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 20, 21, 22 June 20, 21, 22 June, from 11:00 to 12:00 – Main Auditorium, bldg. 500 Climate change and challenges for the environment C. SCHLUECHTER / Univ. Bern, CH The Academic Training is postponed.

  19. Diccionario de lingüística

    Directory of Open Access Journals (Sweden)

    Eduardo Miranda Nelson

    Full Text Available THEODOR LEWANDOWSKI, DICCIONARIO DE LINGUISTICA, Madrid, Ediciones Cátedra, S.A., 1982, XIV, 447 págs. Traducción del alemán por María Luz García-Denche y Enrique Bernárdez.

  20. Mälestusi jalgpallist / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2005-01-01

    Isiklike mälestustega jalgpallihuvilisest noorusest seob autor sakslase Sönke Wortmanni mängufilmi "Berni ime" ("Das Wunder von Bern" ; 2003), mis kajastab sakslaste jalgpalli eufooriat, kui 1954.a. MM-l Saksamaa LV meeskond tuleb maailmameistriks

  1. Improving the Security and Resilience of U.S. Postal Service Mail Products and Services Using the CERT (registered trademark) Resilience Management Model

    Science.gov (United States)

    2014-01-01

    federal statutes addressing electronic crimes, mail fraud, mail theft, identity theft, child exploitation, and prohibited mailings such as bombs and...headquartered in Berne , Switzerland, is a unit of the United Nations that regulates the postal services of 192 member countries. These postal

  2. Prevention of Infections Associated with Combat-Related Burn Injuries

    Science.gov (United States)

    2011-08-01

    that resulted from the bombing of Hiroshima would characterize future conflicts.7 Once estab- lished, the US Army Burn Center focused research efforts...et al. Burn infections. In: Holzheimer RG, Mannick JA, eds. Surgical Treatment-Evidence Based and Problem Oriented. Bern -Weun, New York: W

  3. Leadership in the Shenandoah Valley and North Africa: Historical Studies in Mission Command

    Science.gov (United States)

    2013-06-13

    Confederate defeats at Shiloh, Roanoke Island, and New Bern , it was decided that the most prudent strategy was to attempt to deal with McClellan both......also saw an increase in the Allied bombing offensive with the introduction of the four engine bomber, radio navigation aids, and incendiary bombs

  4. Library science talks : eleventh season 2005

    CERN Document Server

    2005-01-01

    The Swiss National Library in Berne, the Association of International Librarians and Information Specialists AILIS and the CERN Scientific Information Service are pleased to announce their 2005 series of Library Science Talks. The series offers library and archive staff the possibility of learning from and communicating with personalities in library services and organizations. The talks cover important and topical issues for librarians.

  5. Characterization of nine new microsatellite loci for the marbled newt ...

    Indian Academy of Sciences (India)

    Triturus marmoratus is distributed throughout central, west- ern and southern France as well as in a large portion of north- ern Iberia. Despite being categorized as of least concern by the IUCN, it is protected by the Annex IV of the EU Habitats. Directive and the Annex III of the Bern Convention (Arntzen et al. 2009). As most ...

  6. Armillaria ectypa, a rare fungus of mire in Poland

    Directory of Open Access Journals (Sweden)

    Małgorzata Stasińska

    2015-08-01

    Full Text Available Armillaria ectypa is a saprotroph that occurs on active raised bogs and alkaline fens, as well as Aapa mires and transitional bogs. It is a very rare and threatened Eurasian species and one of the 33 fungal species proposed for inclusion into the Bern Convention. Its distribution in Poland, ecological notes and morphology of basidiocarp based on Polish specimens are presented.

  7. How Einstein Discovered "E[subscript 0] = mc[squared]"

    Science.gov (United States)

    Hecht, Eugene

    2012-01-01

    This paper traces Einstein's discovery of "the equivalence of mass [m] and energy ["E[subscript 0]"]." He came to that splendid insight in 1905 while employed by the Bern Patent Office, at which time he was not an especially ardent reader of physics journals. How then did the young savant, working outside of academia in semi-isolation, realize…

  8. Anti-hepatocarcinoma effects of berberine nanosuspension against human HepG2 and Huh7 cells as well as H22 tumor bearing mice

    Science.gov (United States)

    Wang, Zhi-ping; Wu, Jun-biao; Zhou, Qun; Wang, Yi-fei; Chen, Tongsheng

    2014-09-01

    Hepatocarcinoma, a malignant cancer, threaten human life badly. It is a current issue to seek the effective natural remedy from plant to treat cancer due to the resistance of the advanced hepatocarcinoma to chemotherapy. Berberine (Ber), an isoquinoline derivative alkaloid, has a wide range of pharmacological properties and is considered to have anti-hepatocarcinoma effects. However its low oral bioavailability restricts its wide application. In this report, Ber nanosuspension (Ber-NS) composed of Ber and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) was prepared by high pressure homogenization technique. Both in vitro and in vivo anti-hepatocarcinoma effects of Ber-NS relative to effcacy of bulk Ber were evaluated. The particle size and zeta potential of Ber-NS were 73.1 +/- 3.7 nm and 6.99 +/- 0.17 mV, respectively. Ber-NS exhibited significant inhibitory effects against human HepG2 and Huh7 cells, and the corresponding IC50 values were 8.1 and 4.7 μg/ml (18.3 and 6.5 μg/ml of Ber solution). In vivo studies also showed higher antitumor efficacy, and inhibition rates was 63.7% (41.4 % of Ber solution) at 100 mg/kg intragastric administration in the H22 solid tumor bearing mice. These results suggest that the delivery of Ber as a nanosuspension is a promising approach for treating hepatocarcinoma.

  9. Errata Resonance, Vol.20, No.12, 2015. Rajaram Nityananda, Sun ...

    Indian Academy of Sciences (India)

    IAS Admin

    Resonance, Vol.20, No.12, 2015. Rajaram Nityananda, Sun, Sky and Clouds: Where Light and Matter Meet. Page 1121: The correct Figure 5 is reproduced below: Resonance, Vol.20, No.11, 2015. Anil Kumar, Felix Bloch (1905–1983). Page 956: Para 1, Line 5, 'also from Zürich' should be read as 'from nearby Bern'.

  10. Linking Up the Alps: How Networks of Local Political Actors Build the Pan-Alpine Region

    Directory of Open Access Journals (Sweden)

    Clive H. Church

    2017-05-01

    Full Text Available Reviewed: Linking Up the Alps: How Networks of Local Political Actors Build the Pan-Alpine Region By Cristina Del Biaggio. Bern, Switzerland: Peter Lang, 2016. 370 pp. €52.50. ISBN 978-3-0343-1630-9.

  11. Author Details

    African Journals Online (AJOL)

    A computer simulation of a potential derived from the gay-berne potential for lattice model. Abstract PDF · Vol 4, No 2 (1990) - Articles An efficient algorithm for chemical potential computation of anisotropic systems. Abstract PDF · Vol 3, No 2 (1989) - Articles Meanfield theory of the nematic liquid crystal free surface

  12. 100eme anniversaire de la théorie de la relativité Une BD romande : Mélanges Einstein (Albert) et l'histoire de la physique

    CERN Multimedia

    Tesnier, Grégory

    2005-01-01

    2005 has been delcared "Year of Physics" by UNESCO and ONU to celebrate the 100th anniversary of the theory of relativity, elaborated by Einstein (who lived in Bern). To hon. Einstein, an historical comic strip has been published (1 page)

  13. Linear genetic programming for time-series modelling of daily flow rate

    Indian Academy of Sciences (India)

    two versions of Neural Networks (NNs) are used in predicting time-series of daily flow rates at a station on Schuylkill River at Berne, PA, .... function estimate directly from the training data. (Cigizoglu and Alp 2006). ..... Note: Qmean – mean observed discharge, Sx – standard deviation, Qmin – mini- mum observed discharge ...

  14. Drama in Life: The Uses of Communication in Society.

    Science.gov (United States)

    Combs, James E.; Mansfield, Michael W.

    Bringing together 35 of the most notable contributions of authors such as Kenneth Burke, Erving Goffman, and Eric Berne, this book provides an introduction to the dramaturgical perspective of social actions. Selections stem from the conception that many "real-life" actions and events can most adequately be understood in terms of drama. Included…

  15. Compacting coastal plain soils changes midrotation loblolly pine allometry by reducing root biomass

    Science.gov (United States)

    Kim H. Ludovici

    2008-01-01

    Factorial combinations of soil compaction and organic matter removal were replicated at the Long Term Site Productivity study in the Croatan National Forest, near New Bern, North Carolina, USA. Ten years after planting, 18 preselected loblolly pine (Pinus taeda L.) trees were destructively harvested to quantify treatment effects on total above- and...

  16. Reviving Patrika... Inside...

    Indian Academy of Sciences (India)

    (19)Open archives and search engines. Alan Gilchrist/Steven Harnad, UK. 20 September 2000. (20)The strong interactions. Henrich Leutwyler, University of. Bern, Switzerland. 30 August 2000. (21)The influence of Indian mathematics and astronomy in. Iran. Mohammad Bagheri, Encyclopedia. Islamic Foundation Teheran ...

  17. Tõlkeloo arvukad dimensioonid / Hannu K. Riikonen

    Index Scriptorium Estoniae

    Riikonen, Hannu K.

    2012-01-01

    Arvustus: Antonie Chalvin, Anne Lange, Daniele Monticelli (Eds.) Between cultures and texts : itineraries in translation history = Entre les cultures et les textes : itinéraires en histoire de la traduction. Frankfurt am Main-Berlin-Bern-Bruxelles-New York-Oxford-Wien 2011

  18. [Olaf Asendorf. Das Veto des Deutschen Ordens gegen die Erhöhung des Nikolaikirchturmes in Reval] / Paul Kaegbein

    Index Scriptorium Estoniae

    Kaegbein, Paul

    2006-01-01

    Arvustus: Olaf Asendorf. Das Veto des Deutschen Ordens gegen die Erhöhung des Nikolaikirchturmes in Reval. In: Asendorf: Mittelalterliche Türme im deutschordensland Preussen. Frankfurt am Main, Berlin, Bern, New York, Paris, Wien: Lang 1998. S. 105-109. Niguliste kiriku torni ehitusloost

  19. Computer simulation study of water using a fluctuating charge model

    Indian Academy of Sciences (India)

    Unknown

    Abstract. Hydrogen bonding in small water clusters is studied through computer simulation methods using a sophisticated, empirical model of interaction developed by Rick et al (S W Rick, S J Stuart and B J Berne 1994 J. Chem. Phys. 101 6141) and others. The model allows for the charges on the interacting sites to ...

  20. Book Review The politics of language and nation building in ...

    African Journals Online (AJOL)

    Abstract. Peter Lang AG, International Academic Publishers, Bern, Switzerland Africa in Development Volume 2. ISSN 1662-1212. ISBN 978-3-03911-942-4 127 pages. Southern African Linguistics and Applied Language Studies 2012, 30(1): 125–129 ...

  1. Progress Report of the New Solar Submm-Wave Telescope (SST) Installation

    Science.gov (United States)

    Kaufman, P.; Magun, A.; Levato, H.; Rovira, M.; Arzner, K.; Correia, E.; Costa, J. E. R.; Giménez de Castro, C. G.; Kämpfer, N.; Raulin, J.-P.; Rolli, E.; Silva, A. V. R.

    1999-12-01

    The Solar Sub-Millimeter wave Telescope (SST) is now in its final stage of construction and a definite schedule has been established. The 1.5 m diameter reflector has been completed and presents an excellent surface with a deviation of 18 microns (r.m.s.). The reflector construction employed the new "slumping" technique (Martin et al. 1998). The SST building, including one 3.4 m gore-tex radome and a room for optical imaging spectrographs (from IAP, Bern and OV, UFRJ, Brasil), has been completed now at El Leoncito, San Juan, Argentina. Numerous electrical, electronical, mechanical tests, as well as software tests, have been performed at the IAP, Bern, Switzerland, and at Itapetinga, Brasil. The SST was assembled in Bern, consisting of the 1.5 m reflector, four 210 and two 405 GHz radiometers, the positioner, the interface box between the reflector and the radiometers, and the counter-weights. Part of the tests and integration of the SST is beeing done at Bern, with a co-participation of researchers and technicians of CRAAE and CASLEO. The shipment of the SST to El Leoncito will be in February 1999, and the final installation is scheduled for the period March-May 1999. The SST project received main financial support from the Brazilian Agency FAPESP (Proc. 93/3321-7), complemented by funds from the IAFE and CASLEO/CONICET, Argentina, and the IAP, Switzerland.

  2. Atmospheric CO2, d(O2/N2) and d13CO2 measurements at Jungfraujoch, Switzerland: results from a flask sampling intercomparison program

    NARCIS (Netherlands)

    Laan-Luijkx, van der I.T.; Laan, van der S.; Uglietti, C.; Schibig, M.F.; Neubert, R.E.M.; Meijer, H.A.J.; Brand, W.A.; Jordan, A.; Richter, J.M.; Rothe, M.; Leuenberger, M.C.

    2013-01-01

    We present results from an intercomparison program of CO2, d(O2/N2) and d13CO2 measurements from atmospheric flask samples. Flask samples are collected on a bi-weekly basis at the High Altitude Research Station Jungfraujoch in Switzerland for three European laboratories: the University of Bern,

  3. People, Plants, and Patents: The Impact of Intellectual Property on ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The Crucible Group met in June 1993, in Uppsala, Sweden, and in September 1993, in Bern, Switzerland, to hammer out ideas and recommendations on intellectual property. Rather than seeking consensus, The Crucible Group identified trends, concerns, and opportunities in intellectual property issues related to plant ...

  4. 78 FR 8683 - Advisory Committee on International Postal and Delivery Services

    Science.gov (United States)

    2013-02-06

    ... a meeting of the Advisory Committee on International Postal and Delivery Services. This Committee... meeting in Bern, Switzerland, and other subjects related to international postal and delivery services of... DEPARTMENT OF STATE [Public Notice 8178] Advisory Committee on International Postal and Delivery...

  5. Latitudinal variation in the occurrence of GPS L-band scintillations ...

    Indian Academy of Sciences (India)

    TEC (ROT) and the rate of change of TEC index. (ROTI) have been studied by several researchers to ... is also of interest to study the spatial and tempo- ral variabilities of the GPS L-band scintillations in ...... tional GPS Service for Geodynamics, Berne, Switzerland,. March 25–26, 351p. Weber E J, Basu S, Bullett T W, ...

  6. Bam Earthquake in Iran

    CERN Document Server

    2004-01-01

    Following their request for help from members of international organisations, the permanent Mission of the Islamic Republic of Iran has given the following bank account number, where you can donate money to help the victims of the Bam earthquake. Re: Bam earthquake 235 - UBS 311264.35L Bubenberg Platz 3001 BERN

  7. o

    African Journals Online (AJOL)

    , clinical material and overall results. In: Gschwend N, Debrunner G, eds. Total Hip. Prosthesis, Bern: Hans Huber, 1976: 36-48. 5. Zaousis AL, Patikas AF. Experience \\\\~th THA in Greece; the first. 20 years. Clin Orthop 1989; 246: 39-47. . 6.

  8. Nieuwe vondsten van zeldzame planten in 1999 en 2000

    NARCIS (Netherlands)

    Meijden, van der Ruud; Holverda, Wout J.; Slikke, van der Wout J.

    2001-01-01

    The best news is the discovery of a new inland locality of Apium repens, an endangered species included in both the Habitat Directive and the Berne Convention. The List has a striking number of new records of rare ferns: Asplenium adiantum-nigrum, A. septentrionalis, Botrychium lunaria, Ceterach

  9. Grain-boundary engineering applied to grain growth in a high temperature material

    International Nuclear Information System (INIS)

    Huda, Z.

    1993-01-01

    Crystallography of grain boundaries are determined for a high temperature material, before and after grain growth processes, so as to study the induction of special properties useful for application in components of a gas-turbine engine. The philosophy of grain-boundary engineering is applied to grain growth in APK-6, a powder formed nickel-base superalloy so as to establish the possible structure/property relationships. The alloy in the as received condition is shown to possess a strong texture and contained coincident site lattices (CSL) boundaries with most boundaries having sigma values in the range of 3 > sigma > 25. A normal grain-growth heat treatment result in a good population of low angle grain boundaries, and drastically reduces the proportion of CSL boundaries. A strong [011] annealing texture is observed after an intermediate grain growth; most grain boundaries, here, tend to be high angle indicating a possibility of possessing special properties. (author)

  10. Improved memory characteristics by NH3-nitrided GdO as charge storage layer for nonvolatile memory applications

    International Nuclear Information System (INIS)

    Liu, L.; Xu, J. P.; Ji, F.; Chen, J. X.; Lai, P. T.

    2012-01-01

    Charge-trapping memory capacitor with nitrided gadolinium oxide (GdO) as charge storage layer (CSL) is fabricated, and the influence of post-deposition annealing in NH 3 on its memory characteristics is investigated. Transmission electron microscopy, x-ray photoelectron spectroscopy, and x-ray diffraction are used to analyze the cross-section and interface quality, composition, and crystallinity of the stack gate dielectric, respectively. It is found that nitrogen incorporation can improve the memory window and achieve a good trade-off among the memory properties due to NH 3 -annealing-induced reasonable distribution profile of a large quantity of deep-level bulk traps created in the nitrided GdO film and reduction of shallow traps near the CSL/SiO 2 interface.

  11. Production of ethanol from cellulosic biomass by Clostridium thermocellum SS19 in submerged fermentation: screening of nutrients using Plackett-Burman design.

    Science.gov (United States)

    Balusu, Ramesh; Paduru, Rama Mohan R; Seenayya, G; Reddy, G

    2004-06-01

    Plackett-Burman design, a statistical methodology, was used to screen 23 nutrients belonging to three categories--carbon, nitrogen, and salt/mineral sources--for the production of ethanol from cellulosic biomass by Clostridium thermocellum SS19 in anaerobic submerged fermentation. In this design, just n number of experiments is required for screening n-1 variables. The experimental data were subjected to statistical analysis for calculating the regression coefficients and t-values. Filter paper, Solka Floc, corn steep liquor (CSL), cysteine HCl, magnesium chloride, and ferrous sulfate showed relatively higher regression coefficients on ethanol production and growth. Among the 23 nutrients screened, based on their performance in terms of product-promoting ability, availability, and cost, filter paper, CSL, cysteine HCl, magnesium chloride, and ferrous sulfate were identified as the most effective and, therefore, selected for inclusion in further optimization studies. Copryright 2004 Humana Press Inc.

  12. Production of lactic acid from cheese whey by batch and repeated batch cultures of Lactobacillus sp. RKY2.

    Science.gov (United States)

    Kim, Hyang-Ok; Wee, Young-Jung; Kim, Jin-Nam; Yun, Jong-Sun; Ryu, Hwa-Won

    2006-01-01

    The fermentative production of lactic acid from cheese whey and corn steep liquor (CSL) as cheap raw materials was investigated by using Lactobacillus sp. RKY2 in order to develop a cost-effective fermentation medium. Lactic acid yields based on consumed lactose were obtained at more than 0.98 g/g from the medium containing whey lactose. Lactic acid productivities and yields obtained from whey lactose medium were slightly higher than those obtained from pure lactose medium. The lactic acid productivity gradually decreased with increase in substrate concentration owing to substrate and product inhibitions. The fermentation efficiencies were improved by the addition of more CSL to the medium. Moreover, through the cell-recycle repeated batch fermentation, lactic acid productivity was maximized to 6.34 g/L/h, which was 6.2 times higher than that of the batch fermentation.

  13. d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

    DEFF Research Database (Denmark)

    Ruckthong, Leela; Peacock, Anna F.A.; Pascoe, Cherilyn E.

    2017-01-01

    Although metal ion binding to naturally occurring l-amino acid proteins is well documented, understanding the impact of the opposite chirality (d-)amino acids on the structure and stereochemistry of metals is in its infancy. We examine the effect of a d-configuration cysteine within a designed l...... by comparison of the structure of ZnIICl(CSL16DC)3 2- to the published structure of ZnII(H2O)(GRAND-CSL12AL16LC)3 -. Moreover, spectroscopic analysis indicates that the CdII geometry observed by using l-Cys ligands (a mixture of three- and four-coordinate CdII) is altered to a single four-coordinate species...

  14. Effects of GBCD on cold work embrittlement of high strength interstitial free steels

    International Nuclear Information System (INIS)

    Cao, S.Q.; Zhang, J.X.; Wu, J.S.; Chen, J.G.

    2006-01-01

    The effects of grain boundary character distribution (GBCD) on cold work embrittlement (CWE) of P-added high strength interstitial-free (IF) steels have been evaluated using an electron backscatter diffraction (EBSD) technique. It has been found that cracks propagation along the high-energy continuous random boundaries resulted in the CWE, and that low-angle or low-Σ CSL boundaries can offer obstacles to the propagation of cracks. The results indicate that the CWE of high strength IF steels can be improved by an optimum GBCD which is described as a high frequency of low-angle or low-Σ CSL boundaries, and a more discontinuous random boundary network

  15. Improved memory characteristics by NH{sub 3}-nitrided GdO as charge storage layer for nonvolatile memory applications

    Energy Technology Data Exchange (ETDEWEB)

    Liu, L.; Xu, J. P.; Ji, F.; Chen, J. X. [Department of Electronic Science and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); Lai, P. T. [Department of Electrical and Electronic Engineering, University of Hong Kong, Pokfulam Road (Hong Kong)

    2012-07-16

    Charge-trapping memory capacitor with nitrided gadolinium oxide (GdO) as charge storage layer (CSL) is fabricated, and the influence of post-deposition annealing in NH{sub 3} on its memory characteristics is investigated. Transmission electron microscopy, x-ray photoelectron spectroscopy, and x-ray diffraction are used to analyze the cross-section and interface quality, composition, and crystallinity of the stack gate dielectric, respectively. It is found that nitrogen incorporation can improve the memory window and achieve a good trade-off among the memory properties due to NH{sub 3}-annealing-induced reasonable distribution profile of a large quantity of deep-level bulk traps created in the nitrided GdO film and reduction of shallow traps near the CSL/SiO{sub 2} interface.

  16. Chiral spin liquids at finite temperature in a three-dimensional Kitaev model

    Science.gov (United States)

    Kato, Yasuyuki; Kamiya, Yoshitomo; Nasu, Joji; Motome, Yukitoshi

    2017-11-01

    Chiral spin liquids (CSLs) in three dimensions and thermal phase transitions to paramagnet are studied by unbiased Monte Carlo simulations. For an extension of the Kitaev model to a three-dimensional tricoordinate network dubbed the hypernonagon lattice, we derive low-energy effective models in two different anisotropic limits. We show that the effective interactions between the emergent Z2 degrees of freedom called fluxes are unfrustrated in one limit, while highly frustrated in the other. In both cases, we find a first-order phase transition to the CSL, where both time-reversal and parity symmetries are spontaneously broken. In the frustrated case, however, the CSL state is highly exotic—the flux configuration is subextensively degenerate while showing a directional order with broken C3 rotational symmetry. Our results provide two contrasting archetypes of CSLs in three dimensions, both of which allow approximation-free simulation for investigating the thermodynamics.

  17. EBSD characterization of carbide-carbide boundaries in WC-Co composites.

    Science.gov (United States)

    Farooq, M U; Klement, U

    2004-03-01

    A sample of WC-6wt%Co was investigated for grain boundary character distribution and occurrence of coincidence site lattice (CSL) boundaries on a statistical basis. For this purpose orientation measurements of the grains were carried out using electron back-scattered diffraction (EBSD). The dominant misorientation relationships were determined by complementary EBSD data representation tools such as orientation maps, misorientation angle distribution histograms and the sectioned three-dimensional misorientation space. It was found that the grain boundary character distribution of the material is nearly random and the CSL boundaries are not present in statistically significant amounts. It was also found that the amount of binder phase does not play a role in the formation of special boundaries. The paper focuses on the methodology of characterizing grain boundaries in a hexagonal material using EBSD.

  18. IL COACHING STRATEGICO-LINGUISTICO : VERSO UNA SCIENZA DEL CAMBIAMENTO ?

    OpenAIRE

    Lureau, Maxence

    2014-01-01

    We make the most of two concrete experiences of coaching, the first with a linguistic dominance, the second with a psychological dominance, and we try to develop a model of CSL ( Coaching Strategico -Linguistic Programming) .After a brief introduction where we emphasize that this research is not exhaustive but is constantly evolving , we present an overview of psychological approaches : ancient approaches , psychoanalytic , cognitive-behavioral , humanistic , neurolinguistic , transactional a...

  19. Galápagos and Californian sea lions are separate species: Genetic analysis of the genus Zalophus and its implications for conservation management

    OpenAIRE

    Wolf, Jochen BW; Tautz, Diethard; Trillmich, Fritz

    2007-01-01

    Abstract Background Accurate formal taxonomic designations are thought to be of critical importance for the conservation of endangered taxa. The Galápagos sea lion (GSL), being appreciated as a key element of the Galápagos marine ecosystem, has lately been listed as 'vulnerable' by the IUCN. To date there is, however, hardly any scientific evidence, whether it constitutes a separate entity from its abundant Californian neighbour (CSL). In this paper, we delineate the taxonomic relationships w...

  20. Nursing students' perceptions of factors influencing their learning environment in a clinical skills laboratory: A qualitative study.

    Science.gov (United States)

    Haraldseid, Cecilie; Friberg, Febe; Aase, Karina

    2015-09-01

    The mastery of clinical skills learning is required to become a trained nurse. Due to limited opportunities for clinical skills training in clinical practice, undergraduate training at clinical skills laboratories (CSLs) is an essential part of nursing education. In a sociocultural learning perspective learning is situated in an environment. Growing student cohorts, rapid introduction of technology-based teaching methods and a shift from a teaching- to a learning-centered education all influence the environment of the students. These changes also affect CSLs and therefore compel nursing faculties to adapt to the changing learning environment. This study aimed to explore students' perceptions of their learning environment in a clinical skills laboratory, and to increase the knowledge base for improving CSL learning conditions identifying the most important environmental factors according to the students. An exploratory qualitative methodology was used. Nineteen second-year students enrolled in an undergraduate nursing program in Norway participated in the study. They took the same clinical skills course. Eight were part-time students (group A) and 11 were full-time students (group B). Focus group interviews and content analysis were conducted to capture the students' perception of the CSL learning environment. The study documents students' experience of the physical (facilities, material equipment, learning tools, standard procedures), psychosocial (expectations, feedback, relations) and organizational (faculty resources, course structure) factors that affect the CSL learning environment. Creating an authentic environment, facilitating motivation, and providing resources for multiple methods and repetitions within clinical skills training are all important for improving CSL learning environments from the student perspective. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Spectrogram Analysis of Complete Dentures with Different Thickness and Palatal Rugae Materials on Speech Production

    OpenAIRE

    Hamada Zaki Mahross; Kusai Baroudi

    2015-01-01

    Objective. To investigate the influence of reproduction of different thickness and palatal rugae materials on complete dentures speech using Computerized Speech Lab (CSL) (spectrogram). Materials and Methods. Three completely edentulous male patients (aged 50?60 years) were selected for reading a paragraph. Twelve upper dentures were constructed, four for each patient. The patients' speech groups were divided into five groups, Group I: patients without dentures; Group II: patients rehabilitat...

  2. Cherenkov Radiation Detector | Obinabo | Nigerian Journal of ...

    African Journals Online (AJOL)

    ... the radiator is 41.60. It is known that 1.17 MeV Csl37 emits a cone of Cherenkov angle of 450 while the radiator measured 43024' angle. The determined angle for 1.71 MeV beta from p32 is 46014' as against the theoretical value of 470. The simple inexpensive radiator compares favourably with the very expensive heavy ...

  3. Comparing the fermentation performance of Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST and Zymomonas mobilis AX101 for cellulosic ethanol production

    Directory of Open Access Journals (Sweden)

    Dale Bruce E

    2010-05-01

    Full Text Available Abstract Background Fermentations using Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST, and Zymomonas mobilis AX101 are compared side-by-side on corn steep liquor (CSL media and the water extract and enzymatic hydrolysate from ammonia fiber expansion (AFEX-pretreated corn stover. Results The three ethanologens are able produce ethanol from a CSL-supplemented co-fermentation at a metabolic yield, final concentration and rate greater than 0.42 g/g consumed sugars, 40 g/L and 0.7 g/L/h (0-48 h, respectively. Xylose-only fermentation of the tested ethanologenic bacteria are five to eight times faster than 424A(LNH-ST in the CSL fermentation. All tested strains grow and co-ferment sugars at 15% w/v solids loading equivalent of ammonia fiber explosion (AFEX-pretreated corn stover water extract. However, both KO11 and 424A(LNH-ST exhibit higher growth robustness than AX101. In 18% w/w solids loading lignocellulosic hydrolysate from AFEX pretreatment, complete glucose fermentations can be achieved at a rate greater than 0.77 g/L/h. In contrast to results from fermentation in CSL, S. cerevisiae 424A(LNH-ST consumed xylose at the greatest extent and rate in the hydrolysate compared to the bacteria tested. Conclusions Our results confirm that glucose fermentations among the tested strains are effective even at high solids loading (18% by weight. However, xylose consumption in the lignocellulosic hydrolysate is the major bottleneck affecting overall yield, titer or rate of the process. In comparison, Saccharomyces cerevisiae 424A(LNH-ST is the most relevant strains for industrial production for its ability to ferment both glucose and xylose from undetoxified and unsupplemented hydrolysate from AFEX-pretreated corn stover at high yield.

  4. Extracorporeal shock-wave therapy effectively reduces calcaneal spur length and spur-related pain in overweight and obese patients.

    Science.gov (United States)

    Hayta, Emrullah; Salk, Ismail; Gumus, Cesur; Tuncay, Mehmet Siddik; Cetin, Ali

    2016-05-20

    We aimed to evaluate the effects of extra corporeal shock-wave therapy (ESWT) on the calcaneal spur length and pain severity in overweight and obese patients with symptomatic calcaneal spur. In eighty patients with symptomatic calcaneal spur, ESWT was administered on days 0 and 7, and visual analog scale (VAS) scores and calcaneal spur lengths (CSLs) before and 3 months later after treatment were recorded. A lateral heel radiograph was used for computer-aided linear measurements of CSL. Of 80 patients, 59 (73.7%) were female and 21 were male (26.3%); age was 45.9 ± 8.3 years; BMI was 31.6 ± 4.4 kg/m2; and symptom duration was 2.3 ± 2.4 years. The CSL and VAS score after treatment were significantly lower than those before treatment (CSL before vs. after: 5.7 ± 1.0 vs. 4.4 ± 0.9, p = 0.001; VAS score before vs. after: 8.3 ± 1.4 vs. 4.6 ± 2.2; p = 0.03). The CSLs before and after treatment had a significant strong correlation (r = 0.832, p = 0.001). The VAS scores before and after treatment presented a significant mild correlation (r = 0.242, p = 0.03). In overweight and obese patients with symptomatic calcaneal spur, ESWT reduces the CSL and pain severity during a follow-up of three-month duration.

  5. Al Qaeda as a Charismatic Phenomenon

    Science.gov (United States)

    2009-06-01

    79 3. Social Entrepreneurship : Creating an Alternate Ideology 81 B. MEANS TO REDUCE THE LEVEL OF CONTROL IN AL QAEDA... 85 1. Direct...Ocalan: Turkey’s no. 1 Enemy. 77 Rochlin, Vanguard Revolutionaries in Latin America: Peru, Colombia , Mexico, 300. 78 Scheuer, The Plotters Against...Rochlin, Vanguard Revolutionaries in Latin America: Peru, Colombia , Mexico, 300. 31 36.8 percent (7 out of 19) of the conflicts involving a CSL only were

  6. Lysine and Glutamic Acids as the End Products of Multi-response of Optimized Fermented Medium by Mucor mucedo KP736529.

    Science.gov (United States)

    El-Hersh, Mohammed S; Saber, WesamEldin I A; El-Fadaly, Husain A; Mahmoud, Mohammed K

    Amino acids are important for living organisms, they acting as crucial for metabolic activities and energy generation, wherein the deficiency in these amino acids cause various physiological defects. The aim of this study is to investigate the effect of some nutritional factors on the amino acids production by Mucor mucedo KP736529 during fermentation intervals. Mucor mucedo KP736529 was selected according to proteolytic activity. Corn steep liquor and olive cake were used in the fermented medium during Placket-Burman and central composite design to maximize the production of lysine and glutamic acids. During the screening by Plackett-Burman design, olive cake and Corn Steep Liquor (CSL) had potential importance for the higher production of amino acids. The individual fractionation of total amino acids showed both lysine and glutamic as the major amino acids associated with the fermentation process. Moreover, the Central Composite Design (CCD) has been adopted to explain the interaction between olive cake and CSL on the production of lysine and glutamic acids. The model recorded significant F-value, with high values of R 2, adjusted R 2 and predicted R 2 for both lysine and glutamic, indicating the validity of the data. Solving equation for maximum production of lysine recorded theoretical levels of olive cake and CSL, being 2.58 and 1.83 g L -1, respectively, with predicting value of lysine at 1.470 μg mL -1, whereas the predicting value of glutamic acid reached 0.805 mg mL -1 at levels of 2.49 and 1.93 g L -1 from olive cake and CSL, respectively. The desirability function (D) showed the actual responses being 1.473±0.009 and 0.801±0.004 μg mL -1 for lysine and glutamic acids, respectively. The model showed adequate validity to be applied in a large-scale production of both lysine and glutamic acids.

  7. Artificial Intelligence Research at GTE Laboratories (Research in Progress)

    OpenAIRE

    Frawley, William; Goyal, Shri

    1984-01-01

    GTE Laboratories is the central corporate research and development facility for the sixty subsidiaries of the worldwide GTE corporation. Located in the Massachusetts Route 128 high technology area, the five laboratories that comprise GTE Laboratories generate the ideas, products, systems, and services that provide technical leadership for GTE. The two laboratories which conduct artificial intelligence research are the Computer Science Laboratory (CSL) and the Fundamental Research Laboratory (...

  8. Studies on the antimicrobial effect of corn steep liquor on some ...

    African Journals Online (AJOL)

    Using well diffusion method, 0.1 ml (100 μl) of the liquor effectively inhibited the growth of the test organisms with zones of inhibition ranging from 4.00 ± 0.28 to 20.20 ± 0.14 mm. The zones of inhibition increased with increasing number of days of fermentation of the filtrate on which is the CSL. However, there was no ...

  9. Dicty_cDB: CHF523 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available lis cDNA clone TVTD023 5' end, mRNA sequence. 52 2e-13 3 BW529286 |BW529286.1 Ciona savignyi cDNA, clone:csl...v010m05, 5'end, single read. 46 5e-10 6 BW559326 |BW559326.1 Ciona savignyi cDNA, clone:cslv010m05, 3'end, s

  10. Nanophotonic Devices in Silicon for Nonlinear Optics

    Science.gov (United States)

    2010-10-15

    arm length imbalance . A balanced MZI could maximize the optical bandwidth and make the device athermal, however an unbalanced device makes it possible...that the capacitive loading itself could become a limitation; at 1 GHz, the absolute value of the impedance of the two Csl capacitors is around 44Ω, and...metal-oxide- semiconductor capacitor ," Nature, vol. 427, pp. 615-618, 2004. [2] L. Liao, A. Liu, D. Rubin, J. Basak, Y. Chetrit, H. Nguyen, R. Cohen, N

  11. A Cross Structured Light Sensor and Stripe Segmentation Method for Visual Tracking of a Wall Climbing Robot

    Science.gov (United States)

    Zhang, Liguo; Sun, Jianguo; Yin, Guisheng; Zhao, Jing; Han, Qilong

    2015-01-01

    In non-destructive testing (NDT) of metal welds, weld line tracking is usually performed outdoors, where the structured light sources are always disturbed by various noises, such as sunlight, shadows, and reflections from the weld line surface. In this paper, we design a cross structured light (CSL) to detect the weld line and propose a robust laser stripe segmentation algorithm to overcome the noises in structured light images. An adaptive monochromatic space is applied to preprocess the image with ambient noises. In the monochromatic image, the laser stripe obtained is recovered as a multichannel signal by minimum entropy deconvolution. Lastly, the stripe centre points are extracted from the image. In experiments, the CSL sensor and the proposed algorithm are applied to guide a wall climbing robot inspecting the weld line of a wind power tower. The experimental results show that the CSL sensor can capture the 3D information of the welds with high accuracy, and the proposed algorithm contributes to the weld line inspection and the robot navigation. PMID:26110403

  12. Comparative Shear-Bond Strength of Six Dental Self-Adhesive Resin Cements to Zirconia

    Directory of Open Access Journals (Sweden)

    Si-Eun Lee

    2015-06-01

    Full Text Available This study compared shear bond strength (SBS of six self-adhesive resin cements (SARC and one resin-modified glass ionomer cement (RMGIC to zirconia before and after thermocycling. The cylinder shape (Φ 2.35 mm × 3 mm of six SARCs (G-CEM LinkAce (GLA, Maxcem Elite (MAX, Clearfil SA Luting (CSL, PermaCem 2.0 (PM2, Rely-X U200 (RXU, Smartcem 2 (SC2 were bonded to the top surface of the zirconia specimens with light-curing. RMGIC (Fujicem (FJC was bonded to the specimens with self-curing. The shear bond strength of all cemented specimens was measured with universal testing machine. Half of the specimens were thermocycled 5000 times before shear bonding strength testing. Fractured surfaces were examined with a field-emission SEM (10,000× and analyzed by energy dispersive x-ray analysis. MAX, PM2, SC2 group without thermocycling and GLA, MAX, PM2 group with thermocycling showed adhesive failure, but GLA, CSL, RXU, FJC group without thermocycling and SLC, RXU, SC2, FJC group with thermocycling indicated cohesive failure. Within the limitation of this study, All of SARCs except MAX demonstrated higher bond strength than that of RMGIC regardless of thermocycling. Also, SARC containing MDP monomers (CSL retained better bonds than other cements.

  13. Evidence for an association between nonsyndromic cleft lip with or without cleft palate and a gene located on the long arm of chromosome 4

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, L.E.; Healey, S.C.; Chenevix-Trench, G. [St. Louis Univ. Health Sciences Center, MO (United States)]|[Queensland Institute of Medical Research, Brisbane (Australia)

    1995-11-01

    Recent studies suggest that the familial aggregation of nonsyndromic cleft lip with or without cleft palate (CL{+-}P) is likely to be attributable to the effects of several susceptibility loci, acting in a multiplicative fashion. Two potential CL{+-}P susceptibility loci (CSL), transforming growth factor alpha (TGFA) and retinoic acid receptor (RARA), have been identified through association studies. In addition, recent evidence of linkage between CL{+-}P and two markers (D4S175 and D4S192) in the region 4q25-4q31.3 raised the possibility that a CSL, with a larger effect than either TGFA or RARA, may reside within this region of the human genome. The present analyses were undertaken to determine whether D4S175 or D4S192 is significantly associated with CL{+-}P in a sample of unrelated patients that have previously provided evidence of associations between CL{+-}P and both TGFA and RARA. The results of these analyses provide further, tentative, evidence for the presence of a CSL locus on the long arm of chromosome 4 and help to refine the location of this locus in the region of D4S175 and D4S192. 28 refs., 4 tabs.

  14. Economic Optimized Medium for Tensio-Active Agent Production by Candida sphaerica UCP0995 and Application in the Removal of Hydrophobic Contaminant from Sand

    Directory of Open Access Journals (Sweden)

    Galba M. Campos-Takaki

    2011-04-01

    Full Text Available Statistical experimental designs and response surface methodology were employed to optimize the concentrations of agroindustrial residues as soybean oil (SORR from refinery, and corn steep liquor (CSL from corn industry, for tensio-active agent produced by Candida sphaerica UCP 0995. Three 22 full factorial design were applied sequentially to investigate the effects of the concentrations and interactions of soybean oil refinery residue and corn steep liquor on the surface tension of free-cell culture broth for 144 h. Two 22 central composite designs and response surface methodology were adopted to derive a statistical model to measure the effect of SORR and CSL on the surface tension of the free-cell culture broth for 144 h. The regression equation obtained from the experimental data using a central composite design was solved, and by analyzing the response surface contour plots, the optimal concentrations of the constituents of the medium were determined: 8.63% v/v (≈9% v/v of SORR and 8.80% v/v (≈9% v/v CSL. The minimum surface tension predicted and experimentally confirmed was 25.25 mN/m. The new biosurfactant, denominated Lunasan, recovered 95% of motor oil adsorbed in a sand sample, thus showing great potential for use in bioremediation processes, especially in the petroleum industry.

  15. Real-time, resource-constrained object classification on a micro-air vehicle

    Science.gov (United States)

    Buck, Louis; Ray, Laura

    2013-12-01

    A real-time embedded object classification algorithm is developed through the novel combination of binary feature descriptors, a bag-of-visual-words object model and the cortico-striatal loop (CSL) learning algorithm. The BRIEF, ORB and FREAK binary descriptors are tested and compared to SIFT descriptors with regard to their respective classification accuracies, execution times, and memory requirements when used with CSL on a 12.6 g ARM Cortex embedded processor running at 800 MHz. Additionally, the effect of x2 feature mapping and opponent-color representations used with these descriptors is examined. These tests are performed on four data sets of varying sizes and difficulty, and the BRIEF descriptor is found to yield the best combination of speed and classification accuracy. Its use with CSL achieves accuracies between 67% and 95% of those achieved with SIFT descriptors and allows for the embedded classification of a 128x192 pixel image in 0.15 seconds, 60 times faster than classification with SIFT. X2 mapping is found to provide substantial improvements in classification accuracy for all of the descriptors at little cost, while opponent-color descriptors are offer accuracy improvements only on colorful datasets.

  16. Changes in labor patterns over 50 years

    Science.gov (United States)

    Laughon, S. Katherine; Branch, D. Ware; Beaver, Julie; Zhang, Jun

    2013-01-01

    Objective The objective of the study was to examine differences in labor patterns in a modern cohort compared with the 1960s in the United States. Study Design Data from pregnancies at term, in spontaneous labor, with cephalic, singleton fetuses were compared between the Collaborative Perinatal Project (CPP, n = 39,491 delivering 1959-1966) and the Consortium on Safe Labor (CSL; n = 98,359 delivering 2002-2008). Results Compared with the CPP, women in the CSL were older (26.8 ± 6.0 vs 24.1 ± 6.0 years), heavier (body mass index 29.9 ± 5.0 vs 26.3 ±4.1 kg/m2), had higher epidural (55% vs 4%) and oxytocin use (31% vs 12%), and cesarean delivery (12% vs 3%). First stage of labor in the CSL was longer by a median of 2.6 hours in nulliparas and 2.0 hours in multiparas, even after adjusting for maternal and pregnancy characteristics, suggesting that the prolonged labor is mostly due to changes in practice patterns. Conclusion Labor is longer in the modern obstetrical cohort. The benefit of extensive interventions needs further evaluation. PMID:22542117

  17. High-cell-density fed-batch culture of Saccharomyces cerevisiae KV-25 using molasses and corn steep liquor.

    Science.gov (United States)

    Vu, Van Hanh; Kim, Keun

    2009-12-01

    High-cell-density cultivation of yeast was investigated using the agricultural waste products corn steep liquor (CSL) and molasses. The Saccharomyces cerevisiae KV-25 cell mass was significantly dependent on the ratio between C and N sources. The concentrations of molasses and CSL in the culture medium were statistically optimized at 10.25% (v/v) and 16.87% (v/v), respectively, by response surface methodology (RSM). Batch culture in a 5-l stirred tank reactor using the optimized medium resulted in a cell mass production of 36.5 g/l. In the fed-batch culture, the feed phase was preceded by a batch phase using the optimized medium, and a very high dried-cell-mass yield of 187.63 g/l was successfully attained by feeding a mixture of 20% (v/v) molasses and 80% (v/v) CSL at a rate of 22 ml/h. In this system, the production of cell mass depended mainly on the agitation speed, the composition of the feed medium, and the glucose level in the medium, but only slightly on the aeration rate.

  18. Immunostimulatory and anti-metastatic activity of polysaccharides isolated from byproducts of the corn starch industry.

    Science.gov (United States)

    Lee, Sue Jung; Lee, Ho Sung; Kim, Sun Young; Shin, Kwang-Soon

    2018-02-01

    Corn steep liquor (CSL) is a major by-product of the corn steeping process that is utilized in the wet milling industry. To develop new physiologically active polysaccharides from CSL, polysaccharides were isolated and their innate immunostimulatory and anti-metastatic activities were investigated. Corn byproduct polysaccharides (CBP) were preferentially isolated from CSL and further separated into supernatant (CBP1S) and precipitate (CBP1P) fractions. The anti-complementary activity of CBP1S was more potent than CBP1P and CBP. In addition, CBP1S enhanced production of macrophage-stimulating cytokines (e.g., IL-6 and IL-12) and natural killer (NK) cell-activating substances (e.g., granzyme and interferon-γ). Further, CBP1S significantly inhibited lung metastasis at a dose of 1000μg per mouse in an experimental lung metastasis model. These results suggest that CBP1S seems to promote the inhibition of lung metastasis through a mechanism leading to stimulation of the innate immune system, and CBP1S could be used as immunostimulating agents and for industrial applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Modelling the Caspian Sea and its catchment area using a coupled regional atmosphere-ocean model (RegCM4-ROMS: model design and preliminary results

    Directory of Open Access Journals (Sweden)

    U. U. Turuncoglu

    2013-03-01

    Full Text Available We describe the development of a coupled regional atmosphere-ocean model (RegCM4-ROMS and its implementation over the Caspian Sea basin. The coupled model is run for the period 1999–2008 (after a spin up of 4 yr and it is compared to corresponding stand alone model simulations and a simulation in which a distributed 1d lake model is run for the Caspian Sea. All model versions show a good performance in reproducing the climatology of the Caspian Sea basin, with relatively minor differences across them. The coupled ROMS produces realistic, although somewhat overestimated, Caspian Sea Surface Temperature (SST, with a considerable improvement compared to the use of the simpler coupled lake model. Simulated near surface salinity and sea currents are also realistic, although the upwelling over the eastern coastal regions is underestimated. The sea ice extent over the shallow northern shelf of the Caspian Sea and its seasonal evolution are well reproduced, however, a significant negative bias in sea-ice fraction exists due to the relatively poor representation of the bathymetry. ROMS also calculates the Caspian Sea Level (CSL, showing that for the present experiment excessive evaporation over the lake area leads to a drift in estimated CSL. Despite this problem, which requires further analysis due to many uncertainties in the estimation of CSL, overall the coupled RegCM4-ROMS system shows encouraging results in reproducing both the climatology of the region and the basic characteristics of the Caspian Sea.

  20. Bounds on quantum collapse models from matter-wave interferometry: calculational details

    Science.gov (United States)

    Toroš, Marko; Bassi, Angelo

    2018-03-01

    We present a simple derivation of the interference pattern in matter-wave interferometry predicted by a class of quantum master equations. We apply the obtained formulae to the following collapse models: the Ghirardi–Rimini–Weber (GRW) model, the continuous spontaneous localization (CSL) model together with its dissipative (dCSL) and non-Markovian generalizations (cCSL), the quantum mechanics with universal position localization (QMUPL), and the Diósi–Penrose (DP) model. We discuss the separability of the dynamics of the collapse models along the three spatial directions, the validity of the paraxial approximation, and the amplification mechanism. We obtain analytical expressions both in the far field and near field limits. These results agree with those already derived in the Wigner function formalism. We compare the theoretical predictions with the experimental data from two recent matter-wave experiments: the 2012 far-field experiment of Juffmann T et al (2012 Nat. Nanotechnol. 7 297–300) and the 2013 Kapitza–Dirac–Talbot–Lau (KDTL) near-field experiment of Eibenberger et al (2013 Phys. Chem. Chem. Phys. 15 14696–700). We show the region of the parameter space for each collapse model that is excluded by these experiments. We show that matter-wave experiments provide model-insensitive bounds that are valid for a wide family of dissipative and non-Markovian generalizations.

  1. Implementing peer tutoring in a graduate medical education programme.

    Science.gov (United States)

    Salerno-Kennedy, Rossana; Henn, Pat; O'Flynn, Siun

    2010-06-01

    In modern times, peer tutoring methods have been explored in health care education for over 30 years. In this paper, we report our experience of implementing a peer-tutoring approach to Clinical Skills Laboratory (CSL) training in the Graduate Entry in Medicine Programme (GEM) at University College Cork. Eighteen fourth-year medical students were recruited as peer tutors for CSL sessions on physical examination. In order to standardise the process, we developed a training course for peer tutors that comprised two stages. They then ran the practical sessions with junior students, under the watchful eye of medical educators. At the end of the last CSL session, the students were given 10 minutes to reflect individually on the experience, and were asked to complete a feedback form. Twenty-four of the 42 GEM students and six of the seven Senior Tutors (STs) completed and returned their feedback forms. With the caveats of small sample sizes and low response rates, both groups reported that they had both positive and negative experiences of peer tutoring, but that the positive experiences predominated. The overall experience was positive. In terms of the primary thesis of this study, the STs thought that they were well prepared by the teaching staff to take part in these teaching sessions. © Blackwell Publishing Ltd 2010.

  2. Protective effects ofBacillus subtilisagainstSalmonellainfection in the microbiome of Hy-Line Brown layers.

    Science.gov (United States)

    Oh, Ju Kyoung; Pajarillo, Edward Alain B; Chae, Jong Pyo; Kim, In Ho; Kang, Dae-Kyung

    2017-09-01

    This study investigated the effects of Bacillus subtilis CSL2 ( B. subtilis CSL2) administration before Salmonella challenge on the fecal microbiota and microbial functionality of Hy-line Brown (HLB) laying hens. Fecal samples were collected from control (CON), Salmonella -infected (SAL) and Salmonella -infected, probiotic-treated (PRO) groups before and after Salmonella challenge for microbiome analysis using 16S rRNA gene pyrosequencing. Infection with Salmonella led to decreased microbial diversity in hen feces; diversity was recovered with Bacillus administration. In addition, Salmonella infection triggered significant alterations in the composition of the fecal microbiota. The abundance of the phylum Firmicutes decreased while that of Proteobacteria, which includes a wide variety of pathogens, increased significantly. Bacillus administration resulted in normal levels of abundance of Firmicutes and Proteobacteria. Analysis of bacterial genera showed that Salmonella challenge decreased the population of Lactobacillus , the most abundant genus, and increased populations of Pseudomonas and Flavobacterium genera by a factor of 3 to 5. On the other hand, Bacillus administration caused the abundance of the Lactobacillus genus to recover to control levels and decreased the population of Pseudomonas significantly. Further analysis of operational taxonomic units revealed a high abundance of genes associated with two-component systems and secretion systems in the SAL group, whereas the PRO group had more genes associated with ribosomes. The results of this study indicate that B. subtilis CSL2 administration can modulate the microbiota in HLB laying hens, potentially acting as a probiotic to protect against Salmonella Gallinarum infection.

  3. The role of peer assisted learning to improve the effectivity of clinical skill laboratory learning in dental education

    Directory of Open Access Journals (Sweden)

    Agus Ardinansyah

    2016-06-01

    Full Text Available Nowadays, the clinical skill learning in dental education has begun in pre-clinic, known as Clinical Skill Laboratory (CSL which needs human resources, many and expensive tools and manikins, and enough times for practise. One of the method used in CSL in dental education is PeerAssisted Learning (PAL defined as “the development of knowledge and skill through active help and support among status equals or match companions”. This paper aims is to explain the role of PAL method to improve the effectivity of CSL learning in dental education in preclinical stage. Reviewing on the relevant literatures regarding peer assisted learning on the implementation of the clinical skill laboratory in dental education. The effectivity of CSL learning needs close supervision and individual feedback, so enough tutors is important through the process. This PAL method considered to be helpfull with the increasing numbers of dental students and the limitation of staff faculty. This method is found feasible, well accepted by peer-tutors and students, and can be as effective as conventional learning method. This is also useful for peer-teacher because they more intrinsically motivated, have higher conceptual learning scores, and perceive themselves to be more actively engaged with the environment than students who learn in order to be tested.  However, there are several limitation of this method. The contact time between students and medical doctors may decrease significantlyand it does not seem to be generally qualified to transfer such complex procedures.It also needs peer-teachers training and a detailed manual. Questions concerning the cost-effectiveness and profitability of student tutor-guided technical skills training may thus arise. But one institution that implemented this method states that the majority of their tutors decided to continue their teaching activity in the skills lab and that these experienced tutors, in addition to established faculty staff

  4. Frequência populacional de Dermatobia hominis (Linnaeus Jr., 1781 (Diptera: Cuterebridae e sua correlação com variáveis climáticas, no Sudeste do Brasil

    Directory of Open Access Journals (Sweden)

    William Soares Medeiros

    2015-12-01

    Full Text Available Foi avaliada a frequência de infestação por larvas de Dermatobia hominis em bovinos leiteiros, investigando-se a existência de correlação entre a incidência do berne e os fatores climáticos (temperatura, umidade relativa e precipitação pluviométrica com a sua distribuição na superfície corporal dos animais. Foram selecionadas duas áreas localizadas na região Sudeste do Brasil: Área 1: clima subtropical/tropical de altitude (Cwa; Área 2: clima tropical (Aw. As observações foram realizadas no período de maio a dezembro de 2013. Em cada propriedade foram examinados dez animais em coletas de campo quinzenais para o levantamento do número de nódulos de berne. Foram registrados nódulos durante todos os meses de coleta. A Área 1 apresentou média de 12,94 bernes/mês, e a Área 2, 7,58 bernes/mês. Na Área 2, não foi constatada a existência de correlação entre o número de bernes e as variáveis climáticas (p > 0,05. Na Área 1, houve correlação entre o número médio de bernes com a temperatura (p = 0,011 e a precipitação (p = 0,034. Esses fatores climáticos, relacionados às características edáficas, influenciam a penetração das larvas L3 e o período pupal. O maior número de nódulos foi encontrado na região anterior inferior, seguida pela região anterior superior do corpo dos animais, regiões nobres que compõe a parte industrializável da pele do animal e que representam a maior causa de prejuízo econômico.

  5. Putovanja Alberta Fortisa u Ljubljanu

    Directory of Open Access Journals (Sweden)

    Žarko Muljačić

    1975-11-01

    Full Text Available Sredinom rujna 1781. talijanski poligraf i veliki prijatelj naših naroda Alberto Fortis (1741.-1803. i mladi dubrovački vlastelin Tomo Basiljević-Bassegli (1756.-1806. nalazili su se na najtežoj dionici krivudava puta koji je iz Brescie, dolinom Valtellina, preko Poschiava, Chura i Luzerna trebalo da ih dovede u Bern. Fortis je sina svojih dubrovačkih prijatelja pratio u Bern, gdje je trebalo da Basiljević po Fortisovoj zamisli studira kako hi u novoj, za Dubrovčane dotad nepoznatoj protestantskoj sredini upoznao ideje vodilje, metode i težnje prosvjetiteljstva na području društvenih i prirodnih znanosti i tako se osposobio da kasnije postane reformator u svojoj zemlji.

  6. 24 weeks of Pilates-aerobic and educative training to improve body fat mass in elderly Serbian women

    Directory of Open Access Journals (Sweden)

    Rutjes AWS

    2014-04-01

    Full Text Available Anne WS Rutjes,1 Marcello Di Nisio2,31Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; 2Department of Medical, Oral, and Biotechnological Sciences, University G D'Annunzio of Chieti-Pescara, Chieti, Italy; 3Department of Vascular Medicine, Academic Medical Center, Amsterdam, the NetherlandsWe read with interest the article by Ruiz-Montero et al, in which the authors used a before-and-after study design to examine changes in body composition (fat mass and lean body mass related to an aerobic-Pilates program in elderly Serbian women.1 The authors concluded that "a combined program of aerobic and Pilates, carried out under the supervision of an instructor, at least twice a week, produces health benefits in functionally independent women over the age of 60". This conclusion is overly optimistic and not supported by the evidence provided. View original paper by Ruiz-Montero and colleagues.

  7. Particle physics in your pocket!

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    CERN physicists, take out your smartphones! Two new particle physics applications for Android phones have been developed by a physicist from the University of Bern: “Particle Properties” and “Particle Physics Booklet 2010”.   “When I'm on shift, I enjoy looking at the online event displays,” says Igor Kreslo from the Laboratory for High Energy Physics at the University of Bern, the physicist who has developed the two particle physics applications for Android. “Sometimes very beautiful events appear, with many different particles. I like to discuss these displays with my students, just to develop their ability to identify particles. We try to find out which particle is which and how it might decay… I think that's the best way to teach students the phenomenology of particle physics.” When scientists study particle physics, they require some vital information, such as the decay branching ...

  8. Implementation of the person-oriented approach in training in the University of Civil Engineering as a way of forming of the successful professional

    Directory of Open Access Journals (Sweden)

    Portnyagina Elena

    2017-01-01

    Full Text Available The creation of an independent, active, self-fulfilling and thinking professional is an important problem of modern education. In the article we consider the issue of implementation of the person-oriented approach in the psychological and other humanitarian courses in the University of Civil Engineering. Much attention is given to the self-determination theory ofE. Desi and R. Ryan, and transactional analysis of E. Berne. The article includes the research of dominative ego states of bachelor degree students of the Institute of Construction and Architecture (ICA of the Moscow University of Civil Engineering (MGSU. These ego states are considered as the prerequisites of readiness of adoption of independent decisions, acceptances on responsibility for the training. Based on the works of E. Desi, E. Berne, andM.Boekaerts the author has made the practical recommendations for the creation of an independent personality and the establishing of a student as a subject of study.

  9. No limits. eccplus - key to handle flexibility the total processing for power trade; Grenzen ueberwinden. eccplus - Schluessel zur flexiblen Abwicklung der Gesamtprozesse

    Energy Technology Data Exchange (ETDEWEB)

    Wucher, A. [BKW FMB Energie AG, Bern (Switzerland). Abteilung International Marketing and Sales

    2002-07-01

    Power as an export article: The trade with this product is getting over limits of Switzerland. To manage the power supply the Bern BKW FMB Energie AG uses an energy management from Germany. A further advantage is this solution in combination with an EDM- (energy data management) and a complete CRM (Customer relation ship). (GL) [German] Die Grenzen der Schweiz hat die BKW FMB Energie AG in Bern schon laengst ueberschritten. Erfolgreich haben Niederlassungen in Deutschland, Italien und Frankreich Grosskunden akquiriert. 2001 erreichten Handelstaetigkeit und die internationalen Aktivitaeten ein Volumen, das mit den vorhandenen Softwaremitteln nicht mehr zu managen war - es war Zeit fuer ein Energiedatenmanagement, das diese Grenze ueberwindet: eccplus von der deutschen eccplus AG. Als zusaetzliches Plus bringt die Loesung - in Kombination mit dem EDM - auch noch ein vollstaendiges CRM-System mit. (orig.)

  10. Open Access for Social Simulation

    OpenAIRE

    J. Gary Polhill; Bruce Edmonds

    2007-01-01

    We consider here issues of open access to social simulations, with a particular focus on software licences, though also briefly discussing documentation and archiving. Without any specific software licence, the default arrangements are stipulated by the Berne Convention (for those countries adopting it), and are unsuitable for software to be used as part of the scientific process (i.e. simulation software used to generate conclusions that are to be considered part of the scientific domain of ...

  11. Draft Environmental Impact Statement. Maintenance Dredging and Dredged Material Disposal Facility at Harbor Beach, Huron County, Michigan. The Detroit Edison Company Permit Application (Process Number 792253C).

    Science.gov (United States)

    1981-01-01

    House of Representatives Winsor Township Washington, D.C. 20515 204 Berne St. Pigeon, MI 48755 Coast Guard Marine Inspection Of. Mr. Herman Rathke...4 B~~24L& NNL Clif 46 W - ~~ %~* - -~RASO ROAn~-* $ 0 0G l SLAIF, TEIA %ST ALITN C O N IN D R1k.:.CI I THE EMKOIT EDISON COMPANY BIASI WnP S minACS C

  12. Long-term Outcome of Arterial Stroke in Children

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2015-05-01

    Full Text Available Investigators at University Children’s Hospital, Inselspital, and Universities of Bern, Geneva, Basel, and Zurich, Switzerland compared long-term outcome of children (1 month-16 years and young adults (16.1-45 years with arterial ischemic stroke (AIS using prospective data from the Swiss Neuropediatric Stroke Registry and the Adult Bernese stroke registry, between Jan 2000 and Dec 2008.

  13. 77 FR 48550 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-08-14

    ... (Union). 81850 Brunswick/Hatteras New Bern, NC 08/03/12 07/26/12 Yachts (CA50) (Workers). 81851 Thermo Fisher Two Rivers, WI 08/03/12 08/01/12 Scientific (Lab Works Division) (Union). 81852 Microsemi Lawrence... 08/01/12 07/20/12 One-Stop). 81839 Swisher International Jacksonville, FL 08/01/12 07/31/12 (Union...

  14. Worldline Green functions for multiloop diagrams

    International Nuclear Information System (INIS)

    Schmidt, M.G.; Heidelberg Univ.; Schubert, C.

    1994-03-01

    We propose a multiloop generalization of the Bern-Kosower formalism, based on Strassler's approach of evaluating worldline path integrals by worldline Green functions. Those Green functions are explicitly constructed for the basic two-loop graph, and for a loop with an arbitrary number of propagator insertions. For scalar and abelian gauge theories, the resulting integral representations allow to combine whole classes of Feynman diagrams into compact expressions. (orig.)

  15. Armenia, Azerbaijan, and Georgia: Political Developments and Implications for U.S. Interests

    Science.gov (United States)

    2011-04-15

    barrage against its capital, Tskhinvali, while Georgia reported intense bombing of some Georgian villages in the conflict zone by South Ossetian forces...Russian warplanes bombed the outskirts of the capital, Tbilisi, as well as other sites. Russian ships landed troops in Georgia’s breakaway Abkhazia...met in Bern , Switzerland, in Swiss-mediated talks over Georgia’s concerns about Russia’s accession to the WTO. According to Georgian officials

  16. A Primer on Applying Monte Carlo Simulation, Real Options Analysis, Knowledge Value Added, Forecasting, and Portfolio Optimization

    Science.gov (United States)

    2010-02-08

    Certified Risk Analyst (CRA) programs. His books and software are being used at top universities around the world (including the Bern Institute in...astounding accuracy or the escape velocity required to shoot a man from the Earth to the Moon, or drop a smart bomb within a few feet of its target...Enrico Fermi (sometimes referred to as the father of the atomic bomb ) in 1930, when he used a random method to calculate the properties of the newly

  17. Impediments to the effectiveness of the United Nations-African Union Mission in Darfur (UNAMID)

    Science.gov (United States)

    2010-12-01

    rebel movements. 28 These attacks on villages would often start with bombing , followed with attack helicopters, after which the Janjaweed would raid...The Successes and Shortcomings of the African Union in Darfur (Brookings Institution – University of Bern , 2005), 18. 30 Collins, History of Modern...267 S/2010/382 14 July, para. 77. 59 breaches of international human rights and humanitarian law such as bombing of civilians or rape and

  18. A Proven Method for Identifying Security Gaps in International Postal and Transportation Critical Infrastructure

    Science.gov (United States)

    2014-01-01

    services. 1 CERT® is a registered mark of Carnegie Mellon University. CMU/SEI-2013-TN-033 | 2 2 Background The UPU, headquartered in Berne ...the publication date of this document. [CNN 2010] CNN Wire Staff. “Yemen-Based al Qaeda Group Claims Responsibility for Parcel Bomb Plot.” CNN...story.php?storyId=130935022 [Perez 2010] Perez, E.; Entous, A.; & Coker, M. “Yemeni Bombs Target U.S.” Wall Street Journal, October 29, 2010. http

  19. Brijuni Conference (10th), Imaging in Space and Time. Held in Brijuni, Croatia on 28 August-1 September 2006

    Science.gov (United States)

    2006-09-01

    LAWS IN BIOLOGICAL EVOLUTION Sydney Leach LERMA, Observatoire de Paris -Meudon, France My talk will first of all deal with power laws in present day...Observatoire de Paris (France) The description of the shape of our physical space at various scales (length scales or energy scales) involves a rich...University of Split University of Zagreb Split, Croatia Zagreb, Croatia angel @ irb.hr Christine Bollinger Damir Aumiler University of Bern Institute of

  20. Walking In The Footsteps of Einstein: Why History of Physics Aids Physics Education

    Science.gov (United States)

    Kortemeyer, Gerd

    2014-03-01

    We twice organized and led a European Study Abroad course to explore the early history of relativity and quantum theory. The course led us to Munich, Bern, Berlin, Zurich, Copenhagen, and Göttingen. The talk describes the sites, impressions, experiences, academics, logistics, and learning outcomes of our courses. It also addresses how some of the aspects of the history of physics can and should be used in teaching regular physics courses.

  1. Die Ehe spaziert nicht auf der Strasse

    Directory of Open Access Journals (Sweden)

    Sigrid Nieberle

    2005-07-01

    Full Text Available Caroline Arni rekonstruiert die Ehe und die Erfahrungen in der Ehe von ihrem Ende her, indem sie Scheidungsakten aus Bern um 1900 untersucht und auswertet. Aus diesen Analysen des „offenkundigen Unglücks“ wird hervorragend nachvollziehbar, wie eine soziokulturelle Institution in die Krise geriet, die im Laufe des 20. Jahrhunderts von Lebensformen wie Lebenspartnerschaften und patchwork families Konkurrenz bekam. Arni gelingt es, aus staubigen Aktenbergen eine kurzweilige und überaus forschungsinnovative Studie zu gewinnen.

  2. First runs with the ORPHEUS dark matter detector

    CERN Document Server

    Czapek, G; Hauser, M; Janos, S; Loaiza, P; Moser, U; Pretzl, K; Brandt, B V D; Konter, J A; Mango, S; Ebert, T; Kainer, K U; Knoop, K M

    2002-01-01

    The ORPHEUS dark matter experiment is completed at our shallow depth laboratory in Bern (70 m.w.e.). The detector relies on measuring the magnetic flux variation produced by weakly interacting massive particles (WIMPs) as they heat 30 mu m diameter superheated superconducting tin granules (SSG) and induce superconducting-to-normal phase transitions. In an initial phase, 0.45 kg of tin granules in a segmented detector volume have been used. Preliminary results of the experiment will be reported.

  3. Using transactional analysis to understand the supervisory process.

    Science.gov (United States)

    Holyoake, D D

    Most literature on supervision praises its ability to create space for reflection, but seldom explores the disabling effects. Using the experiences of four nurses, this article makes use of Berne's Transactional Analysis model as a method for illuminating patterns within supervision. The article concludes that the confessional nature of clinical supervision reflects contemporary practice and the implications of supervision really appear to be an undercover policing or enforcement of cultural/management objectives.

  4. DNA fingerprinting in botany: past, present, future

    OpenAIRE

    Nybom, Hilde; Weising, Kurt; Rotter, Björn

    2014-01-01

    Almost three decades ago Alec Jeffreys published his seminal Nature papers on the use of minisatellite probes for DNA fingerprinting of humans (Jeffreys and colleagues Nature 1985, 314:67–73 and Nature 1985, 316:76–79). The new technology was soon adopted for many other organisms including plants, and when Hilde Nybom, Kurt Weising and Alec Jeffreys first met at the very First International Conference on DNA Fingerprinting in Berne, Switzerland, in 1990, everybody was enthusiastic about the n...

  5. [Sketches of Swiss psychiatry in the generation after Eugen Bleuler and Sigmund Freud. With personal recollections].

    Science.gov (United States)

    Weber, Kaspar

    2009-01-01

    Focussing on the leading staff of the psychiatric universitiy clinic of Waldau/Bern, the author sketches the reception of psychoanalysis in Switzerland around 1940. It ranged from outright rejection (Ernst Grünthal) via various forms of skepticism based on superficial (Jakob Klaesi) or thorough familiarity with Freud's writings (Jakob Wyrsch, Arnold Weber) to the discipleship of an analysand of Freud (Ernst Blum).

  6. BOOK REVIEWS

    OpenAIRE

    Urška Strle; Deianira Ganga,

    2008-01-01

    Reviews of; Historical and Cultural Perspectives on Slovenian Migration by Drnovšek Marjan (ed.) (2007) Ljubljana: Institute for Slovenian Emigration Studies, 204 pp. (ISBN 978-961-254-043-2); Migration, Gender and National Identity: Spanish Migrant Women in London Ana Bravo Moreno (2006) Peter Lang, Oxford, Bern, Berlin, Bruxelles, Frankfurt am Main, New York Wien (ISBN 3-03910-156-0). Key words Slovenian migration; Cultural Perspectives; Migration Policy; Migration and Gender; Identity; Spa...

  7. Assessment of residency program outcomes via alumni surveys

    Directory of Open Access Journals (Sweden)

    Lüer S

    2017-04-01

    Full Text Available Sonja Lüer, Christoph Aebi Department of Pediatrics, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland Background: One trend in medical education is outcomes-oriented training. Outcomes usually refer to individuals’ acquisition of competencies, for example, during training in residency programs. However, little is known about outcomes of these programs. In order to fill this gap, human resource (HR data were analyzed and alumni of a pediatric residency program were surveyed at the Department of Pediatrics, Bern University Hospital, Switzerland.Methods: Residency program outcomes (demographics, career choices, part-time or full-time work status, competencies, feedback were assessed through in-house HR databases, publicly available data on the Internet (physician directory and practice homepages, and 2 alumni surveys (S1, S2. Results: In all, 109 alumni met the inclusion criteria. Retention rate at the hospital was low (14%. Forty-six alumni (42% in private practice were eligible for alumni surveys. Response rates were 87% (S1 and 61% (S2. Time intervals between 2 career decisions (selecting specialty of pediatrics vs selecting setting of private practice varied widely (late-training decision to enter private practice. Mean employment level in private practice was 60% (range 20%–100%. Most valued rotation was emergency medicine; most desired competencies in future colleagues were the ability to work in a team, proficiency in pediatrics, and working economically.Conclusion: A broadened view on outcomes – beyond individuals’ competency acquisition – provides informative insights into a training program, can allow for informed program updates, and guide future program development. Keywords: medical education, career choice, pediatrics, private practice

  8. Computer assisted functional analysis. Computer gestuetzte funktionelle Analyse

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, H.A.E.; Roesler, H.

    1982-01-01

    The latest developments in computer-assisted functional analysis (CFA) in nuclear medicine are presented in about 250 papers of the 19th international annual meeting of the Society of Nuclear Medicine (Bern, September 1981). Apart from the mathematical and instrumental aspects of CFA, computerized emission tomography is given particular attention. Advances in nuclear medical diagnosis in the fields of radiopharmaceuticals, cardiology, angiology, neurology, ophthalmology, pulmonology, gastroenterology, nephrology, endocrinology, oncology and osteology are discussed.

  9. For information - Geneva University: The search for the QCD phase transition / SEMINAIRE ANNULE ! ! !

    CERN Multimedia

    Université de Genève

    2005-01-01

    Ecole de physique Département de physique nucléaire et corspusculaire 24, Quai Ernest-Ansermet 1211 GENEVE 4 TéL: (022) 379 62 73 Fax: (022) 379 69 92 Wednesday 1st June 2005 PARTICLE PHYSICS SEMINAR at 17.00 hrs - Stückelberg Auditorium The search for the QCD phase transition by Prof. Sonja Kabana, Université de Berne SEMINAIRE ANNULE ! ! ! Information : http://dpnc.unige.ch/seminaire/annonce.html Organizer : A. Cervera Villanueva

  10. Cyber Infrastructure Protection. Volume 2

    Science.gov (United States)

    2013-05-01

    programs designed to either conceal or encrypt malicious code so it could be sent and activated un- detected by antivirus programs. These tools were...Classification of Com- puter Viruses, Bern, Switzerland: Metropolitan Network BBS Inc., 2003, available from www.avp.ch/avpve/ classes /classes.stm; P. Szor, The...ticlass taxonomy of hackers. His hacker class taxono- my includes classes of hackers such as petty thieves, old guard hackers, professional

  11. Technologies for Highly Manoeuvrable Aircraft (Les Technologies pour les Aeronefs a Haute Manoeuvrabilite)

    Science.gov (United States)

    1994-03-01

    increasing their sientific and technical potential: - Rendering scientific and technical assistance, as rcquested. to other NATO bodies and to member...todinologloe In sewsrsJ hls of a commo3n Today. i American Aerospace Industry is facing JTAGG Tech Demo. monfewy sues of maio proPoton. Slgtwat prollt...bern built by the main contra-tots RI (Rockwell DA is used for further dama conversion and signal International Corporation’s North American Air

  12. Achievements and Challenges in the Science of Space Weather

    Science.gov (United States)

    Koskinen, Hannu E. J.; Baker, Daniel N.; Balogh, André; Gombosi, Tamas; Veronig, Astrid; von Steiger, Rudolf

    2017-11-01

    In June 2016 a group of 40 space weather scientists attended the workshop on Scientific Foundations of Space Weather at the International Space Science Institute in Bern. In this lead article to the volume based on the talks and discussions during the workshop we review some of main past achievements in the field and outline some of the challenges that the science of space weather is facing today and in the future.

  13. Buchbesprechungen

    OpenAIRE

    1996-01-01

    Holler-Nowitzki, B. (1994): Psychosomatische Beschwerden im Jugendalter. Schulische Belastungen, Zukunftsangst und Streß-Reaktionen. Weinheim. Harnach-Beck, V. (1995)- Psychosoziale Diagnostik in der Jugendhilfe. Weinheim. Ermert, C. (1995): Spielverhalten im Scenotest. Entwicklung und Erprobung von Beobachtungssystemen bei Kindern im Vorschulalter. Bern. Holtstiege, H. (1994): Montessori-Pädagogik und soziale Humanität. Freiburg. Mogel, H. (1994): Psychologie des Kinderspiels...

  14. Majetková práva a licenční smlouva

    OpenAIRE

    Pevný, Jan

    2011-01-01

    Property rights and the licensing agreement Nowadays copyright is more important than it ever used to be. Cause of this importance is the development of society and mainly new technologies of communication which emerged not long ago, particularly Internet. Copyright in the Czech republic is based on dualistic conception, thereby we distinguish moral rights of author from property rights of author (that is in accordance with Berne convention article 6 bis). In the Czech law only property right...

  15. Narrative Journalism in the Age of the Internet. New Ways to Create Authenticity in Online Literary Reportages

    Directory of Open Access Journals (Sweden)

    Nora Berning

    2011-11-01

    Full Text Available Online literary reportages represent an imperative counterweight to conventional journalism that is essential both for our emotional and intellectual survival. Using Paula Delgado-Kling’s online literary reportage Child Soldiers: Homero and Mark Bowden’s multimedia text The Desert One Debacle as examples, Nora Berning explores issues of multimediality and authenticity in online narrative journalism. Berning’s case studies open up discussions, both theoretical and practical, about the future of digital media literacy.

  16. Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma

    Czech Academy of Sciences Publication Activity Database

    Pomeisl, Karel; Votruba, Ivan; Holý, Antonín; Pohl, Radek

    2007-01-01

    Roč. 26, 8/9 (2007), s. 1025-1028 ISSN 1525-7770. [International Roundtable /17./. Bern, 03.09.2006-07.09.2006] R&D Projects: GA MŠk 1M0508 Grant - others:Descartes Prize(XE) HPAW-CT-2002-9001 Institutional research plan: CEZ:AV0Z40550506 Keywords : acyclic nucleoside phosphonates * thymidine phosphorylase * pyrimidines * FPMP derivatives * fluor ination Subject RIV: CC - Organic Chemistry Impact factor: 0.723, year: 2007

  17. Buchbesprechungen

    OpenAIRE

    1984-01-01

    Rezensionen folgender Werke: Minuchin, Fishman, H.Cb. (1983): Praxis der strukturellen Familientherapie, Strategien und Techniken. Freiburg im Breisgau. Rett, A. (1983) Mongolismus. Biologische, erzieherische und soziale Aspekte 2. , ergänzte und überarbeitete Auflage. Erschienen als Band 9 der Reihe "Arbeiten zur Theorie und Praxis der Rehabilitation in Medizin, Psychologie und Sonderpädagogik" Bern. Flackenberg, W. (1983): Die psycho-soziale Situation von Geschwistern behinderte...

  18. Evaluation of a multiprofessional, nonsurgical obesity treatment program: which parameters indicated life style changes and weight loss?

    Science.gov (United States)

    Pjanic; Müller, Roland; Laimer, Markus; Hagenbuch, Niels; Laederach, Kurt; Stanga, Zeno

    2017-01-01

    According to the current evidence, behavior modifications are an effective part of a non-surgical multiprofessional obesity treatment program (MOTP). The purpose of the present study was to report changes in weight as well in psychological variables during a one year MOTP. We aimed to identify the associations of emotional state and patients' emotion regulation skills with weight change. Prospective interventional study. Data of participants attending the one year obesity treatment in either a group or individual structured MOTP were analyzed. Weight, BMI (Body Mass Index) and measures on psychosomatic variables, emotion regulation skills, affective state, shame and guilt were collected at baseline, after three months and after one year. Mixed-effects models were used for the statistical analysis of BMI. We included 238 patients at baseline (t1), 234 after three months (t2) and 179 after one year (t3). A drop in BMI measurements of at least 5% was observed in 20.6% of participants at t2 and 41.4% of participants at t3. After three months, participants showed significant improvements in the following psychosomatic variables: somatisation ( p  psychological aspects like depression, emotion regulation skills, body awareness, and acceptance should be a vital part of an interdisciplinary MOPT. Ethical approval for the present study was obtained from the Bern Kantonal Ethics Committee (KEK-Bern-Study Nr 258/14), Bern, Switzerland.

  19. Genetic strain modification of a live rabies virus vaccine widely used in Europe for wildlife oral vaccination.

    Science.gov (United States)

    Cliquet, Florence; Robardet, Emmanuelle; Picard Meyer, Evelyne

    2013-10-01

    In Europe, the main reservoir and vector of rabies has been the red fox (Vulpes vulpes). Oral immunization of foxes with live vaccines, using attenuated rabies strains (SAD B19, SAD Bern), apathogenic mutants of an attenuated strain (SAG2) and the vaccinia-rabies glycoprotein recombinant virus vaccine (V-RG), has been shown to be the most effective method for the control and elimination of rabies. Among all vaccines currently used for wildlife oral vaccination, one vaccine (marketed as SAD Bern strain) has been widely used in Europe since 1992 with the distribution of 17million of baits in 2011. Because of the potential environmental safety risk of a live virus which could revert to virulence, the full genome sequencing of this vaccine was undertaken and the sequence was characterized and compared with those of referenced rabies viruses. The vaccine showed higher similarity to the strains belonging to the SAD B19 vaccine virus strains than to the SAD Bern vaccines. This study is the first one reporting on virus strain identity changes in this attenuated vaccine. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Games people play the psychology of human relationships

    CERN Document Server

    Berne, Eric

    2010-01-01

    The bestselling Games People Play is the book that has helped millions of people understand the dynamics of relationships, by psychiatrist Eric Berne.We all play games. In every encounter with other people we are doing so. The nature of these games depends both on the situation and on who we meet.Eric Berne's classic Games People Play is the most accessible and insightful book ever written about the games we play: those patterns of behaviour that reveal hidden feelings and emotions. Wise and witty, it shows the underlying motivations behind our relationships and explores the roles that we try to play - and are forced to play.Games People Play gives you the keys to unlock the psychology of others - and yourself. You'll become more honest, more effective, and a true team player.'A brilliant, amusing, and clear catalogue of the psychological theatricals that human beings play over and over again' Kurt VonnegutEric Berne was a prominent psychiatrist and bestselling author.After inventing his groundbreaking Transa...

  1. Protective effects of against infection in the microbiome of Hy-Line Brown layers

    Directory of Open Access Journals (Sweden)

    Ju Kyoung Oh

    2017-09-01

    Full Text Available Objective This study investigated the effects of Bacillus subtilis CSL2 (B. subtilis CSL2 administration before Salmonella challenge on the fecal microbiota and microbial functionality of Hy-line Brown (HLB laying hens. Methods Fecal samples were collected from control (CON, Salmonella-infected (SAL and Salmonella-infected, probiotic-treated (PRO groups before and after Salmonella challenge for microbiome analysis using 16S rRNA gene pyrosequencing. Results Infection with Salmonella led to decreased microbial diversity in hen feces; diversity was recovered with Bacillus administration. In addition, Salmonella infection triggered significant alterations in the composition of the fecal microbiota. The abundance of the phylum Firmicutes decreased while that of Proteobacteria, which includes a wide variety of pathogens, increased significantly. Bacillus administration resulted in normal levels of abundance of Firmicutes and Proteobacteria. Analysis of bacterial genera showed that Salmonella challenge decreased the population of Lactobacillus, the most abundant genus, and increased populations of Pseudomonas and Flavobacterium genera by a factor of 3 to 5. On the other hand, Bacillus administration caused the abundance of the Lactobacillus genus to recover to control levels and decreased the population of Pseudomonas significantly. Further analysis of operational taxonomic units revealed a high abundance of genes associated with two-component systems and secretion systems in the SAL group, whereas the PRO group had more genes associated with ribosomes. Conclusion The results of this study indicate that B. subtilis CSL2 administration can modulate the microbiota in HLB laying hens, potentially acting as a probiotic to protect against Salmonella Gallinarum infection.

  2. Biomimetic fiber assembled gradient hydrogel to engineer glycosaminoglycan enriched and mineralized cartilage: An in vitro study.

    Science.gov (United States)

    Mohan, Neethu; Wilson, Jijo; Joseph, Dexy; Vaikkath, Dhanesh; Nair, Prabha D

    2015-12-01

    The study investigated the potential of electrospun fiber assembled hydrogel, with physical gradients of chondroitin sulfate (CS) and sol-gel-derived bioactive glass (BG), to engineer hyaline and mineralized cartilage in a single 3D system. Electrospun poly(caprolactone) (PCL) fibers incorporated with 0.1% w/w of CS (CSL) and 0.5% w/w of CS (CSH), 2.4% w/w of BG (BGL) and 12.5% w/w of BG (BGH) were fabricated. The CS showed a sustained release up to 3 days from CSL and 14 days from CSH fibers. Chondrocytes secreted hyaline like matrix with higher sulfated glycosaminoglycans (sGAG), collagen type II and aggrecan on CSL and CSH fibers. Mineralization was observed on BGL and BGH fibers when incubated in simulated body fluid for 14 days. Chondrocytes cultured on these fibers secreted a mineralized matrix that consisted of sGAG, hypertrophic proteins, collagen type X, and osteocalcin. The CS and BG incorporated PCL fiber mats were assembled in an agarose-gelatin hydrogel to generate a 3D hybrid scaffold. The signals in the fibers diffused and generated continuous opposing gradients of CS (chondrogenic signal) and BG (mineralization) in the hydrogel. The chondrocytes were encapsulated in hybrid scaffolds; live dead assay at 48 h showed viable cells. Cells maintained their phenotype and secreted specific extracellular matrix (ECM) in response to signals within the hydrogel. Continuous opposing gradients of sGAG enriched and mineralized ECM were observed surrounding each cell clusters on gradient hydrogel after 14 days of culture in response to the physical gradients of raw materials CS and BG. A construct with gradient mineralization might accelerate integration to subchondral bone during in vivo regeneration. © 2015 Wiley Periodicals, Inc.

  3. Proteasas alcalinas de una cepa nativa de Bacillus sp Alcalofílico Proteasas alcalinas de una cepa nativa de Bacillus sp Alcalofílico

    Directory of Open Access Journals (Sweden)

    A. Sáez Vega

    2006-06-01

    Full Text Available Se evaluó el efecto de cuatro fuentes de nitrógeno sobre la actividad enzimática de proteasas alcalinas, secretadas por una cepa nativa de Bacillus sp Alcalofílico, cultivada a diferentes concentraciones de LMF (Licor de Maíz Fermentado. El crecimiento de la cepa no es afectado por los pH de inoculación de 7,0; 8,5 y 9,5; en contraste con la actividad enzimática y producción de proteína verdadera, que tuvieron sus mejores resultados a pH inicial de 8,5. A este pH se evaluaron dos fuentes de nitrógeno orgánico (extracto de levadura y peptona y dos inorgánicos (NH4Cl y NaNO3The effect of four nitrogen sources on the enzymatic activity of alkaline proteases from a wild strain of Alkalophilic Bacillus sp cultivated to different concentrations from CSL (Corn Steep Liquor. was evaluated. The growth of the strain is not affected by pH of inoculation of 7,0, 8,5 and 9,5, in contrast to the enzymatic activity and true protein production, that had their better results to initial pH of 8,5. To this initial pH of 8,5; two organic nitrogen sources (yeast extract and peptone and two inorganic ones were evaluated (NH4Cl and NaNO3. With peptone the best enzymatic activity to a relation appeared to molar C/N between 1 and 2 was found. For the studied interval of % CSL (0,5 to 2% p/v the concentration of the CSL does not affect the enzymatic activity.

  4. The effect of 2% niacinamide on facial sebum production.

    Science.gov (United States)

    Draelos, Zoe Diana; Matsubara, Akira; Smiles, Kenneth

    2006-06-01

    The presence of sebum on the face is responsible for both facial shine and the formation of comedonal and inflammatory acne lesions. Sebum control is a goal of many OTC skin care products; however, most currently available products function by absorbing sebum from the face rather than modulating its production. To demonstrate the effect of topical 2% niacinamide on sebum excretion rates and casual sebum production in Oriental and Caucasian populations. Separate clinical trials were conducted in both Japan and the USA to evaluate the effect of topical 2% niacinamide in different ethnic groups. A total of 100 Japanese subjects were enrolled in a double-blind, placebo-controlled comparison between two independent balanced groups. Fifty subjects applied the 2% niacinamide moisturizer to the face for 4 weeks and 50 subjects used a placebo moisturizer for 4 weeks, with sebum excretion rate (SER) measurements taken at baseline, week 2, and week 4. In addition, 30 Caucasian subjects were enrolled in a randomized split-face study for 6 weeks with SER and casual sebum levels (CSL) measured at baseline, week 3, and week 6. The results of the Japanese study demonstrated that the SER of the two groups was not significantly different at baseline, but the 2% niacinamide treated group demonstrated significantly lowered SER after 2 and 4 weeks of application. The results were somewhat different in the Caucasian study. After 6 weeks of treatment, the CSL was significantly reduced, but the SER was not significantly reduced. Topical 2% niacinamide may be effective in lowering the SER in Japanese individuals and CSL in Caucasian individuals.

  5. Cloning and characterization of pyruvate carboxylase gene responsible for calcium malate overproduction in Penicillium viticola 152 and its expression analysis.

    Science.gov (United States)

    Khan, Ibrar; Qayyum, Sadia; Ahmed, Shehzad; Maqbool, Farhana; Tauseef, Isfahan; Haleem, Kashif Syed; Chi, Zhen-Ming

    2017-03-20

    In this study, a pyruvate carboxylase gene (PYC) from a marine fungus Penicillium viticola 152 isolated from marine algae was cloned and characterized by using Genome Walking method. An open reading frame (ORF) of The PYC gene (accession number: KM593097) had 3582bp encoding 1193 amino acid protein (isoelectric point: 5.01) with a calculated molecular weight of 131.2757kDa. A putative promoter (intronless) of the gene was located at -666bp and contained a TATA box, several CAAT boxes, the 5'-SYGGRG-3' and a 5'-HGATAR-3' sequences. A consensus polyadenylation site (AATAAA) was also observed at +10bp downstream of the ORF. The protein deduced from the PYC gene had no signal peptide, was a homotetramer (4), and had the four functional domains. Furthermore, PYC protein also had three potential N-linked glycosylation sites, among them, -N-S-T-I- at 36 amino acid, -N-G-T-V- at 237 amino acid, and -N-G-S-S- at 517 amino acid were the most possible N-glycosylation sites. After expression of the PYC gene of P. viticola 152 in medium supplemented with CSL and biotin, it was found that the specific pyruvate carboxylase activity in MA production medium supplemented with CSL was much higher (0.5U/mg) than in MA medium supplemented with biotin (0.3U/mg), suggesting that optimal concentration of CSL is required for increased expression of the PYC gene, which is responsible for high level production of malic acid in P. viticola 152 strain. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Functional changes in people with different hearing status and experiences of using Chinese sign language: an fMRI study.

    Science.gov (United States)

    Li, Qiang; Xia, Shuang; Zhao, Fei; Qi, Ji

    2014-01-01

    The purpose of this study was to assess functional changes in the cerebral cortex in people with different sign language experience and hearing status whilst observing and imitating Chinese Sign Language (CSL) using functional magnetic resonance imaging (fMRI). 50 participants took part in the study, and were divided into four groups according to their hearing status and experience of using sign language: prelingual deafness signer group (PDS), normal hearing non-signer group (HnS), native signer group with normal hearing (HNS), and acquired signer group with normal hearing (HLS). fMRI images were scanned from all subjects when they performed block-designed tasks that involved observing and imitating sign language stimuli. Nine activation areas were found in response to undertaking either observation or imitation CSL tasks and three activated areas were found only when undertaking the imitation task. Of those, the PDS group had significantly greater activation areas in terms of the cluster size of the activated voxels in the bilateral superior parietal lobule, cuneate lobe and lingual gyrus in response to undertaking either the observation or the imitation CSL task than the HnS, HNS and HLS groups. The PDS group also showed significantly greater activation in the bilateral inferior frontal gyrus which was also found in the HNS or the HLS groups but not in the HnS group. This indicates that deaf signers have better sign language proficiency, because they engage more actively with the phonetic and semantic elements. In addition, the activations of the bilateral superior temporal gyrus and inferior parietal lobule were only found in the PDS group and HNS group, and not in the other two groups, which indicates that the area for sign language processing appears to be sensitive to the age of language acquisition. After reading this article, readers will be able to: discuss the relationship between sign language and its neural mechanisms. Copyright © 2014 Elsevier Inc

  7. CBR-D Tactical Decision Aid (DECAID) Identification and Analysis of Predictive Human Performance Models and Data Bases for Use in a Commander’s CBR-D Decision Aid (DECAID)

    Science.gov (United States)

    1988-10-15

    CHEMICAL AGENTS, CROC-TR-84053 AUTHOR: R.F. MCHUGH, R.J. MIODUSZEWSKI, A.P. MICKIEWICZ , J.H. THOMPSON, J.W. JAMESON, P.A. BROOME, E.G. DAVIS ORIGINATING...PRECISION MISSION SCENARIO, ARCSL-TR-81083 AUTHOR: V.R. CLARE, A.P. MICKIEWICZ ORIGINATING ORG: CHEMICAL SYSTEMS LABORATORY(CSL), ABERDEEN PROVING GRO...AGENTS, CRDC-TR-84053 B - 26 AUTHOR: R.F. MCHUGH, R.J. MIODUSZEWSKI, A.P. MICKIEWICZ , J.H. m THOMPSON, J.W. JAMESON, P.A. BROOME, E.G. DAVIS ORIGINATING

  8. The Collins Center Update. Volume 1, Issue 3, December 1999

    Science.gov (United States)

    1999-12-01

    CDN), devel oped and executed the FORO DE ESTRATEGIA NACIONAL 2005 Hon­ du ras en el Siglo XXI (FEN 2005) {Na tional Strategy Forum 2005 Hon du­ ras...that partici pated included the Air Force Space Command, Air Combat Com mand, U. S . Atlan tic Fleet, and U.S. Pa cific Fleet. The CSL team provided...tools and processes used to make strate gic leaders. Im­ pressed with this program, Gover nor Pat ton requested a return visit with his en tire

  9. “Citation Style Language” Uygulaması: APA Kaynak Gösterme Biçiminin Türkçeye Adaptasyonu=“Citation Style Language” Application: The Adaptation of APA Style to Turkish Language

    Directory of Open Access Journals (Sweden)

    Kasım Binici

    2013-10-01

    Full Text Available Bibliyografya yönetim programları, araştırma metinlerin yazımında yazarlara büyük avantajlar sağlamaktadır.Akademik çevrede EndNote, RefWorks, Zotero, Mendeley en popüler yazılımlardır. Türkçe kaynak gösterme kurallarının tanımlı olduğu biçim dosyalarının olmaması nedeniyle araştırma metni yazımında bu programlar işlevsiz kalmaktadır. Bu çalışmada, APA kaynak gösterme biçiminin Türkçeye adaptasyonu sağlanarak CSL uygulaması ile biçim dosyasında kodlar yazılmıştır. Yeni biçim dosyası Zotero ve Mendeley programlarında çalışabilirliği test edilerek kişilerin kullanımına sunulmuştur. Çalışma neticesinde oluşturulan APA-TR dosyası sayesinde Türkçe araştırma metinlerinin yazımında CSL uygulamasını tercih eden bibli- yografya yönetim yazılımların kullanımı mümkün olmuştur./Bibliography managment tools provide great advantage for researchers with writing their articles or research papers. In academic environment, EndNote, RefWorks, Zotero, Mendeley are the most popular software programms. Due to the lack of style files in which citation rules in Turkish language are described,these softwares stay functionless. In this study by providing turkish adaptation of APA citation style, new codes were written into the style file via CSL application. New style file is presented to users after testing its workability in Zotero and Mendeley programms. Thanks to APA-TR style file created as a result of the study,it is possibble to use bibliography managment tools which prefer CSL application in writing research papers Turkish language.

  10. Impacts and adaptation of the cropping systems to climate change in the Northeast Farming Region of China

    DEFF Research Database (Denmark)

    Yin, Xiaogang; Olesen, Jørgen Eivind; Wang, M.

    2016-01-01

    The Northeast Farming Region of China (NFR) is a very important crop growing area, comprising seven sub-regions: Xing’anling (XA), Sanjiang (SJ), Northwest Songliao (NSL), Central Songliao (CSL), Southwest Songliao (SSL), Changbaishan (CB) and Liaodong (LD), which has been severely affected...... to become more severe for crop production under climate change. Adaptation measures that have already been implemented in recent decades to cope with current climatic limitations include changes in timing of cultivation, variety choice, soil tillage practices, crop protection, irrigation and use of plastic...

  11. Thermoregulation in peripheral nerve injury-induced cold-intolerant rats.

    Science.gov (United States)

    Duraku, L S; Smits, E S; Niehof, S P; Hovius, S E R; Walbeehm, E T; Selles, R W

    2012-06-01

    Cold intolerance is defined as pain after exposure to non-painful cold. It is suggested that cold intolerance may be related to dysfunctional thermoregulation in upper extremity nerve injury patients. The purpose of this study was to examine if the re-warming of a rat hind paw is altered in different peripheral nerve injury models and if these patterns are related to severity of cold intolerance. In the spared nerve injury (SNI) and complete sciatic lesion (CSL) model, the re-warming patterns after cold stress exposure were investigated preoperatively and at 3, 6 and 9 weeks postoperatively with a device to induce cooling of the hind paws. Thermocouples were attached on the dorsal side of the hind paw to monitor re-warming patterns. The Von Frey test and cold plate test indicated a significantly lower paw-withdrawal threshold and latency in the SNI compared to the Sham model. The CSL group, however, had only significantly lower paw-withdrawal latency on the cold plate test compared to the Sham group. While we found no significantly different re-warming patterns in the SNI and CSL group compared to Sham group, we did find a tendency in temperature increase in the CSL group 3 weeks postoperatively. Overall, our findings indicate that re-warming patterns are not altered after peripheral nerve injury in these rat models despite the fact that these animals did develop cold intolerance. This suggests that disturbed thermoregulation may not be the prime mechanism for cold intolerance and that, other, most likely, neurological mechanisms may play a more important role. There is no direct correlation between cold intolerance and re-warming patterns in different peripheral nerve injury rat models. This is an important finding for future developing treatments for this common problem, since treatment focussing on vaso-regulation may not help diminish symptoms of cold-intolerant patients. Copyright © 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons

  12. Brewer's spent grain and corn steep liquor as alternative culture medium substrates for proteinase production by Streptomyces malaysiensis AMT-3.

    Science.gov (United States)

    do Nascimento, Rodrigo Pires; Junior, Nelson Alves; Coelho, Rosalie Reed Rodrigues

    2011-10-01

    Brewer's spent grain and corn steep liquor or yeast extract were used as the sole organic forms for proteinase production by Streptomyces malaysiensis in submerged fermentation. The influence of the C and N concentrations, as well as the incubation periods, were assessed. Eight proteolytic bands were detected through gelatin-gel-electrophoresis in the various extracts obtained from the different media and after different incubation periods, with apparent molecular masses of 20, 35, 43, 50, 70, 100, 116 and 212 kDa. The results obtained suggest an opportunity for exploring this alternative strategy for proteinases production by actinomycetes, using BSG and CSL as economically feasible substrates.

  13. Brewer's spent grain and corn steep liquor as alternative culture medium substrates for proteinase production by Streptomyces malaysiensis AMT-3

    Directory of Open Access Journals (Sweden)

    Rodrigo Pires do Nascimento

    2011-12-01

    Full Text Available Brewer's spent grain and corn steep liquor or yeast extract were used as the sole organic forms for proteinase production by Streptomyces malaysiensis in submerged fermentation. The influence of the C and N concentrations, as well as the incubation periods, were assessed. Eight proteolytic bands were detected through gelatin-gel-electrophoresis in the various extracts obtained from the different media and after different incubation periods, with apparent molecular masses of 20, 35, 43, 50, 70, 100, 116 and 212 kDa. The results obtained suggest an opportunity for exploring this alternative strategy for proteinases production by actinomycetes, using BSG and CSL as economically feasible substrates.

  14. Daddy’s Car: Artificial Intelligence as a Creative Tool for Copyright

    Directory of Open Access Journals (Sweden)

    Jaime Alberto Díaz Limón

    2016-12-01

    Full Text Available This year on September 19th, Sony CSL, a software developer company, announced to the world, the creation of the first musical work whose ownership belongs to Artificial Intelligence. This paper analyzes the legal consequences of such a statement, and it’s conceptual and legal limits within the Copyright Universe (with fundament on International Treaties; in order to assess whether we are in presence of new legal-authorial figure that invite us to think over the subjects of protection in our laws or whether the applicable normativity may resolve these hypotheses in favor Artificial Intelligence, instead of juridical persons.

  15. Enhanced production and characterization of a novel β- D-glucose ...

    African Journals Online (AJOL)

    Optimum production of glucose oxidase from A. niger UV-180-C was carried out by using CSL (2%), fermentation period (36 h), pH (5.5 and 4.5 for wild and mutant respectively), temperature (30°C), MgSO4.7H2O (0.0%), CaCO3 (0.1%), KH2PO4 (0.8 and 1.0% for wild and mutant strains), Urea (0.3%). Crude enzyme was ...

  16. State vector reduction - 1: Dynamical reduction theories; changing quantum theory so the statevector represents reality

    International Nuclear Information System (INIS)

    Ghirardi, G.C.; Pearle, P.

    1991-02-01

    The propositions, that what we see around us is real and that reality should be represented by the statevector, conflict with quantum theory. In quantum theory, the statevector can readily become a sum of states of comparable norm, each state representing a different reality. In this paper we present the Continuous Spontaneous Localization (CSL) theory, in which a modified Schroedinger equation, while scarcely affecting the dynamics of a microscopic system, rapidly ''reduces'' the statevector of a macroscopic system to a state appropriate for representing individual reality. (author). Refs

  17. State vector reduction - 2: Elements of physical reality, nonlocality and stochasticity in relativistic dynamical reduction models

    International Nuclear Information System (INIS)

    Ghirardi, G.C.; Pearle, P.

    1991-02-01

    The problem of getting a relativistic generalization of the CSL dynamical reduction model, which has been presented in part I, is discussed. In so doing we have the opportunity to introduce the idea of a stochastically invariant theory. The theoretical model we present, that satisfies this kind of invariance requirement, offers us the possibility to reconsider, from a new point of view, some conceptually relevant issues such as nonlocality, the legitimacy of attributing elements of physical reality to physical systems and the problem of establishing causal relations between physical events. (author). Refs, 3 figs

  18. Streptomyces misionensis PESB-25 Produces a Thermoacidophilic Endoglucanase Using Sugarcane Bagasse and Corn Steep Liquor as the Sole Organic Substrates

    Science.gov (United States)

    Rezende, Raquel de Carvalho; Gravina-Oliveira, Mônica Pires; Pereira, Pedro Henrique Freitas; do Nascimento, Rodrigo Pires; Bon, Elba Pinto da Silva; Macrae, Andrew; Coelho, Rosalie Reed Rodrigues

    2013-01-01

    Streptomyces misionensis strain PESB-25 was screened and selected for its ability to secrete cellulases. Cells were grown in a liquid medium containing sugarcane bagasse (SCB) as carbon source and corn steep liquor (CSL) as nitrogen source, whose concentrations were optimized using response surface methodology (RSM). A peak of endoglucanase accumulation (1.01 U·mL−1) was observed in a medium with SCB 1.0% (w/v) and CSL 1.2% (w/v) within three days of cultivation. S. misionensis PESB-25 endoglucanase activity was thermoacidophilic with optimum pH and temperature range of 3.0 to 3.6 and 62° to 70°C, respectively. In these conditions, values of 1.54 U mL−1 of endoglucanase activity were observed. Moreover, Mn2+ was demonstrated to have a hyperactivating effect on the enzyme. In the presence of MnSO4 (8 mM), the enzyme activity increased threefold, up to 4.34 U·mL−1. Mn2+ also improved endoglucanase stability as the catalyst retained almost full activity upon incubation at 50°C for 4 h, while in the absence of Mn2+, enzyme activity decreased by 50% in this same period. Three protein bands with endoglucanase activity and apparent molecular masses of 12, 48.5 and 119.5 kDa were detected by zymogram. PMID:23586048

  19. Cesium-137 as a radiation source

    International Nuclear Information System (INIS)

    McMullen, W.H.; Sloan, D.P.

    1985-01-01

    The U.S. Department of Energy (DOE) Byproducts Utilization Program (BUP) seeks to develop and encourage widespread commercial use of defense byproducts that are produced by DOE. Cesium-l37 is one such byproduct that is radioactive and decays with emission of gamma rays. The beneficial use of this radiation to disinfect sewage sludge or disinfest food commodities is actively being pursued by the program. The radiation produced by cesium-l37(Cs-l37) is identical in form to that produced by cobalt-60(Co-60), an isotope that is widely used in commercial applications such as medical product sterilization. The choice of isotope to use depends on several factors ranging from inherent properties of the isotopes to availability and cost. The BUP, although centrally concerned with the beneficial use of Cs-l37, by investigating and assessing the feasibility of various uses hopes to define appropriate circumstances where cesium or cobalt might best be used to accomplish specific objectives. This paper discusses some of the factors that should be considered when evaluating potential uses for isotopic sources

  20. Correlation of the crystal orientation and electrical properties of silicon thin films on glass crystallized by line focus diode laser

    Energy Technology Data Exchange (ETDEWEB)

    Yun, J., E-mail: j.yun@unsw.edu.au [School of Photovoltaic and Renewable Energy Engineering, University of New South Wales, Sydney, NSW 2052 (Australia); Huang, J.; Teal, A. [School of Photovoltaic and Renewable Energy Engineering, University of New South Wales, Sydney, NSW 2052 (Australia); Kim, K. [School of Photovoltaic and Renewable Energy Engineering, University of New South Wales, Sydney, NSW 2052 (Australia); Suntech R& D Australia, Botany, NSW 2019 (Australia); Varlamov, S.; Green, M.A. [School of Photovoltaic and Renewable Energy Engineering, University of New South Wales, Sydney, NSW 2052 (Australia)

    2016-06-30

    In this work, crystallographic orientation of polycrystalline silicon films on glass formed by continuous wave diode laser crystallization was studied. Most of the grain boundaries were coincidence lattice Σ3 twin boundaries and other types of boundaries such as, Σ6, Σ9, and Σ21 were also frequently observed. The highest photoluminescence signal and mobility were observed for a grain with (100) orientation in the normal direction. X-ray diffraction results showed the highest occupancies between 41 and 70% along the (110) orientation. However, the highest occupancies changed to (100) orientation when a 100 nm thick SiO{sub x} capping layer was applied. Suns-Voc measurement and photoluminescence showed that higher solar cell performance is obtained from the cell crystallized with the capping layer, which is suspected from increased occupancies of (100) orientation. - Highlights: • Linear grains parallel to the scan direction formed with high density. • Σ3 coincidence lattice (CSL) boundaries found inside a grain • Grain boundaries exhibit various CSL boundaries such as Σ9, Σ18, and Σ27. • Grain with < 100 > orientation in normal direction showed highest electrical properties. • Improved voltage observed when percentage of < 100 > normal orientation is increased.

  1. Model prediction of frost tolerance as related to winter survival of wheat in Finnish field trials

    Directory of Open Access Journals (Sweden)

    A.K. BERGJORD

    2008-12-01

    Full Text Available The model FROSTOL simulates course of frost tolerance in winter wheat on a daily basis from sowing on as affected by soil temperature (2 cm, snow cover, phenological development, and a genotypic maximum level of frost tolerance (LT50. A series of cultivar trials in Finland was used to evaluate the model's ability to estimate plant survival in natural field environments during winters with differing weather conditions. Recorded survival was compared with number of intersections between the curves of simulated LT50 and the soil temperature curve for each field. A cumulative stress level (CSL was calculated based both on number of intersections and FROSTOL simulated stress levels. The correlation between CSL and field recordings was quite low. While the field trials characterize a general ability to stand various types of winter stress, FROSTOL estimates damage caused by the soil temperature regime only. However, FROSTOL simulations seemed to correspond reasonably well to field observations when low temperature was the eventual cause of damage.

  2. Vector magnetometer based on synchronous manipulation of nitrogen-vacancy centers in all crystal directions

    Science.gov (United States)

    Zhang, Chen; Yuan, Heng; Zhang, Ning; Xu, Lixia; Zhang, Jixing; Li, Bo; Fang, Jiancheng

    2018-04-01

    Negatively charged nitrogen vacancy (NV‑) centers in diamond have been extensively studied as high-sensitivity magnetometers, showcasing a wide range of applications. This study experimentally demonstrates a vector magnetometry scheme based on synchronous manipulation of NV‑ center ensembles in all crystal directions using double frequency microwaves (MWs) and multi-coupled-strip-lines (mCSL) waveguide. The application of the mCSL waveguide ensures a high degree of synchrony (99%) for manipulating NV‑ centers in multiple orientations in a large volume. Manipulation with double frequency MWs makes NV‑ centers of all four crystal directions involved, and additionally leads to an enhancement of the manipulation field. In this work, by monitoring the changes in the slope of the resonance line consisting of multi-axes NV‑ centers, measurement of the direction of the external field vector was demonstrated with a sensitivity of {{10}\\prime}/\\sqrt{Hz} . Based on the scheme, the fluorescence signal contrast was improved by four times higher and the sensitivity to the magnetic field strength was improved by two times. The method provides a more practical way of achieving vector sensors based on NV‑ center ensembles in diamond.

  3. Key team physical and technical performance indicators indicative of team quality in the soccer Chinese super league.

    Science.gov (United States)

    Yang, Gai; Leicht, Anthony S; Lago, Carlos; Gómez, Miguel-Ángel

    2018-01-01

    The aim of this study was to identify the key physical and technical performance variables related to team quality in the Chinese Super League (CSL). Teams' performance variables were collected from 240 matches and analysed via analysis of variance between end-of-season-ranked groups and multinomial logistic regression. Significant physical performance differences between groups were identified for sprinting (top-ranked group vs. upper-middle-ranked group) and total distance covered without possession (upper and upper-middle-ranked groups and lower-ranked group). For technical performance, teams in the top-ranked group exhibited a significantly greater amount of possession in opponent's half, number of entry passes in the final 1/3 of the field and the Penalty Area, and 50-50 challenges than lower-ranked teams. Finally, time of possession increased the probability of a win compared with a draw. The current study identified key performance indicators that differentiated end-season team quality within the CSL.

  4. Crystal interface and high-resolution electron microscopy—the best partner

    Directory of Open Access Journals (Sweden)

    H Ichinose

    2000-01-01

    Full Text Available Several contributions of HRTEM on the interface science are reviewed in chronological order. The first contribution of HRTEM is the observation of gold (113Σ°11 boundary, giving experimental proof of the CSL model. An observation of the asymmetric (112Σ°3 boundary follows. A SiC grain boundary is effectively assessed not by the density of CSL point but the number of dangling bonds in the boundary. A ZnO/Pd interface provides an example that a misfit dislocation does not necessarily accommodate the lattice mismatch. Segregated interface shows characteristic HRTEM image contrast, suggesting change in atomic bonding. An atomic height step in the semiconductor hetero interface is observed by the Chemical Lattice Image technique. In the diamond grain boundary a dangling bond may not elevate the boundary energy, being contradictory of the least dangling bond rule. Super-high resolution of the HVHRTEM enable us to determine atomic species in the grain boundary. Combined use of HRTEM and EELSE allows us to discuss the correlation between atomic structure and nature of the corresponding interface. It is not exaggeration to say that modern interface science does not exist witout HRTEM. On the other hand, many complicated interfaces found by HRTEM remained as unaswered questions. An innovative structural model is requested to appear on the scene.

  5. Improved ethanol tolerance and ethanol production from glycerol in a streptomycin-resistant Klebsiella variicola mutant obtained by ribosome engineering.

    Science.gov (United States)

    Suzuki, Toshihiro; Seta, Kohei; Nishikawa, Chiaki; Hara, Eri; Shigeno, Toshiya; Nakajima-Kambe, Toshiaki

    2015-01-01

    To improve the ethanol tolerance of the Klebsiella variicola strain TB-83, we obtained the streptomycin-resistant, ethanol-tolerant mutant strain TB-83D by a ribosome engineering approach. Strain TB-83D was able to grow in the presence of 7% (v/v) ethanol and it showed higher ethanol production than strain TB-83. Examination of various culture conditions revealed that yeast extract was essential for ethanol production and bacterial growth. In addition, ethanol production was elevated to 32g/L by the addition of yeast extract; however, ethanol production was inhibited by formate accumulation. With regard to cost reduction, the use of corn steep liquor (CSL) markedly decreased the formate concentration, and 34g/L ethanol was produced by combining yeast extract with CSL. Our study is the first to improve ethanol tolerance and productivity by a ribosome engineering approach, and we found that strain TB-83D is effective for ethanol production from glycerol. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Production of chlorothalonil hydrolytic dehalogenase from agro-industrial wastewater and its application in raw food cleaning.

    Science.gov (United States)

    He, Qin; Xu, Xi-Hui; Zhang, Fan; Tai, Yu-Kai; Luo, Yan-Fei; He, Jian; Hong, Qing; Jiang, Jian-Dong; Yan, Xin

    2017-06-01

    To reduce the fermentation cost for industrialization of chlorothalonil hydrolytic dehalogenase (Chd), agro-industrial wastewaters including molasses, corn steep liquor (CSL) and fermentation wastewater were used to substitute for expensive carbon and nitrogen sources and fresh water for lab preparation. The results showed that molasses and CSL could replace 5% carbon source and 100% organic nitrogen source respectively to maintain the same fermentation level. Re-fermentation from raffinate of ultra-filtered fermentation wastewater could achieve 61.03% of initial Chd activity and reach 96.39% activity when cultured in a mixture of raffinate and 50% of original medium constituent. Typical raw foods were chosen to evaluate the chlorothalonil removal ability of Chd. After Chd treatment for 2 h at room temperature, 97.40 and 75.55% of 30 mg kg -1 chlorothalonil on cherry tomato and strawberry respectively and 60.29% of 50 mg kg -1 chlorothalonil on Chinese cabbage were removed. Furthermore, the residual activity of the enzyme remained at 78-82% after treatment, suggesting its potential for reuse. This study proved the cost-feasibility of large-scale production of Chd from agro-industrial wastewater and demonstrated the potential of Chd in raw food cleaning. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  7. Comparing three experiential learning methods and their effect on medical students' attitudes to learning communication skills.

    Science.gov (United States)

    Koponen, Jonna; Pyörälä, Eeva; Isotalus, Pekka

    2012-01-01

    Despite numerous studies exploring medical students' attitudes to communication skills learning (CSL), there are apparently no studies comparing different experiential learning methods and their influence on students' attitudes. We compared medical students' attitudes to learning communication skills before and after a communication course in the data as a whole, by gender and when divided into three groups using different methods. Second-year medical students (n = 129) were randomly assigned to three groups. In group A (n = 42) the theatre in education method, in group B (n = 44) simulated patients and in group C (n = 43) role-play were used. The data were gathered before and after the course using Communication Skills Attitude Scale. Students' positive attitudes to learning communication skills (PAS; positive attitude scale) increased significantly and their negative attitudes (NAS; negative attitude scale) decreased significantly between the beginning and end of the course. Female students had more positive attitudes than the male students. There were no significant differences in the three groups in the mean scores for PAS or NAS measured before or after the course. The use of experiential methods and integrating communication skills training with visits to health centres may help medical students to appreciate the importance of CSL.

  8. [Effects of combined application of culture supernatant of human umbilical cord mesenchymal stem cells and ciprofloxacin onStaphylococcus aureusin vitro].

    Science.gov (United States)

    Zhou, B; Tu, H L; Ba, T; Wang, L F; Wang, S J; Nie, S Y

    2017-06-20

    Objective: To explore the effects of combined application of culture supernatant of human umbilical cord mesenchymal stem cells (hUCMSCs) and ciprofloxacin on Staphylococcus aureus (SA) in vitro. Methods: hUCMSCs were isolated from umbilical cord tissue of full-term healthy fetus after cesarean section and cultured. Cells in the third passage were used in the experiments after identification. SA strains isolated from wounds of burn patients in our burn wards were used in the experiments. Cells were divided into 0, 10, 100, and 1 000 ng/mL lipopolysaccharide (LPS) groups according to the random number table (the same dividing method below). Cells were cultured with culture medium of mesenchymal stem cells (MSCs) after being treated with medium containing the corresponding mass concentrations of LPS for 12 h. At post culture hour (PCH) 6, 12, and 24, 6 wells of culture supernatant of cells in each group were obtained to measure the content of LL-37 with enzyme-linked immunosorbent assay. Ninety blood agar plates were divided into ciprofloxacin control group (CC), ciprofloxacin+ supernatant group (CS), and ciprofloxacin+ supernatant+ LL-37 antibody group (CSL), with 30 blood agar plates in each group. Blood agar plates in group CC were coated with 1.5×10(8) colony forming unit (CFU)/mL bacteria solution prepared with normal saline. Blood agar plates in group CS were coated with 1.5×10(8) CFU/mL bacteria solution prepared with normal saline and culture supernatant of hUCMSCs (cultured by culture medium of MSCs, the same below) in double volume of normal saline. Blood agar plates in group CSL were coated with 1.5×10(8) CFU/mL bacteria solution prepared with normal saline, culture supernatant of hUCMSCs in double volume of normal saline, and 2.6 μL LL-37 antibody in the concentration of 2 μg/mL. At PCH 12, 24, and 48, 10 blood agar plates of each group were harvested to observe the distribution of SA colony on blood agar plate and to measure the diameter of

  9. Shell occupation by the hermit crab Dardanus insignis (Decapoda, Diogenidae from the north Coast of São Paulo state, Brazil

    Directory of Open Access Journals (Sweden)

    I. F. Frameschi

    Full Text Available Abstract The pattern of shell occupation by the hermit crab Dardanus insignis (Saussure, 1858 from the subtropical region of southeastern coast of Brazil was investigated in the present study. The percentage of shell types that were occupied and the morphometric relationships between hermit crabs and occupied shells were analyzed from monthly collections conducted during two years (from January 1998 to December 1999. Individuals were categorized according to sex and gonadal maturation, weighed and measured with respect to their cephalothoracic shield length (CSL and wet weight (CWW. Shells were measured regarding their aperture width (SAW, dry weight (SDW and internal volume (SIV. A total of 1086 hermit crabs was collected, occupying shells of 11 gastropod species. Olivancillaria urceus (Roding, 1798 was most commonly used by the hermit crab D. insignis, followed by Buccinanops cochlidium (Dillwyn, 1817, and Stramonita haemastoma (Linnaeus, 1767. The highest determination coefficients (r2 > 0.50, p < 0.01 were recorded particularly in the morphometric relationships between CSL vs. CWW and SAW vs. SIV, which are important indication that in this D. insignis population the great majority the animals occupied adequate shells during the two years analysed. The high number of used shell species and relative plasticity in pattern of shell utilization by smaller individuals of D. insignis indicated that occupation is influenced by the shell availability, while larger individuals demonstrated more specialized occupation in Tonna galea (Linnaeus, 1758 shell.

  10. Grain-boundary type and distribution in silicon carbide coatings and wafers

    Science.gov (United States)

    Cancino-Trejo, Felix; López-Honorato, Eddie; Walker, Ross C.; Ferrer, Romelia Salomon

    2018-03-01

    Silicon carbide is the main diffusion barrier against metallic fission products in TRISO (tristructural isotropic) coated fuel particles. The explanation of the accelerated diffusion of silver through SiC has remained a challenge for more than four decades. Although, it is now well accepted that silver diffuse through SiC by grain boundary diffusion, little is known about the characteristics of the grain boundaries in SiC and how these change depending on the type of sample. In this work five different types (coatings and wafers) of SiC produced by chemical vapor deposition were characterized by electron backscatter diffraction (EBSD). The SiC in TRISO particles had a higher concentration of high angle grain boundaries (aprox. 70%) compared to SiC wafers, which ranged between 30 and 60%. Similarly, SiC wafers had a higher concentration of low angle grain boundaries ranging between 15 and 30%, whereas TRISO particles only reached values of around 7%. The same trend remained when comparing the content of coincidence site lattice (CSL) boundaries, since SiC wafers showed a concentration of more than 30%, whilst TRISO particles had contents of around 20%. In all samples the largest fractions of CSL boundaries (3 ≤ Σ ≤ 17) were the Σ3 boundaries. We show that there are important differences between the SiC in TRISO particles and SiC wafers which could explain some of the differences observed in diffusion experiments in the literature.

  11. Comparative studies of the venom of a new Taipan species, Oxyuranus temporalis, with other members of its genus.

    Science.gov (United States)

    Barber, Carmel M; Madaras, Frank; Turnbull, Richard K; Morley, Terry; Dunstan, Nathan; Allen, Luke; Kuchel, Tim; Mirtschin, Peter; Hodgson, Wayne C

    2014-07-02

    Taipans are highly venomous Australo-Papuan elapids. A new species of taipan, the Western Desert Taipan (Oxyuranus temporalis), has been discovered with two specimens housed in captivity at the Adelaide Zoo. This study is the first investigation of O. temporalis venom and seeks to characterise and compare the neurotoxicity, lethality and biochemical properties of O. temporalis venom with other taipan venoms. Analysis of O. temporalis venom using size-exclusion and reverse-phase HPLC indicated a markedly simplified "profile" compared to other taipan venoms. SDS-PAGE and agarose gel electrophoresis analysis also indicated a relatively simple composition. Murine LD50 studies showed that O. temporalis venom is less lethal than O. microlepidotus venom. Venoms were tested in vitro, using the chick biventer cervicis nerve-muscle preparation. Based on t90 values, O. temporalis venom is highly neurotoxic abolishing indirect twitches far more rapidly than other taipan venoms. O. temporalis venom also abolished responses to exogenous acetylcholine and carbachol, indicating the presence of postsynaptic neurotoxins. Prior administration of CSL Taipan antivenom (CSL Limited) neutralised the inhibitory effects of all taipan venoms. The results of this study suggest that the venom of the O. temporalis is highly neurotoxic in vitro and may contain procoagulant toxins, making this snake potentially dangerous to humans.

  12. Nonparadoxical loss of information in black hole evaporation in a quantum collapse model

    Science.gov (United States)

    Modak, Sujoy K.; Ortíz, Leonardo; Peña, Igor; Sudarsky, Daniel

    2015-06-01

    We consider a novel approach to address the black hole information paradox. The idea is based on adapting, to the situation at hand, the modified versions of quantum theory involving spontaneous stochastic dynamical collapse of quantum states, which have been considered in attempts to deal with shortcomings of the standard Copenhagen interpretation of quantum mechanics, in particular, the issue known as "the measurement problem." The new basic hypothesis is that the modified quantum behavior is enhanced in the region of high curvature so that the information encoded in the initial quantum state of the matter fields is rapidly erased as the black hole singularity is approached. We show that in this manner the complete evaporation of the black hole via Hawking radiation can be understood as involving no paradox. Calculations are performed using a modified version of quantum theory known as "continuous spontaneous localization" (CSL), which was originally developed in the context of many-particle nonrelativistic quantum mechanics. We use a version of CSL tailored to quantum field theory and applied in the context of the two -dimensional Callan-Giddings-Harvey-Strominger model. Although the role of quantum gravity in this picture is restricted to the resolution of the singularity, related studies suggest that there might be further connections.

  13. Use of Hot Rolling for Generating Low Deviation Twins and a Disconnected Random Boundary Network in Inconel 600 Alloy

    Science.gov (United States)

    Sahu, Sandeep; Yadav, Prabhat Chand; Shekhar, Shashank

    2018-02-01

    In this investigation, Inconel 600 alloy was thermomechanically processed to different strains via hot rolling followed by a short-time annealing treatment to determine an appropriate thermomechanical process to achieve a high fraction of low-Σ CSL boundaries. Experimental results demonstrate that a certain level of deformation is necessary to obtain effective "grain boundary engineering"; i.e., the deformation must be sufficiently high to provide the required driving force for postdeformation static recrystallization, yet it should be low enough to retain a large fraction of original twin boundaries. Samples processed in such a fashion exhibited 77 pct length fraction of low-Σ CSL boundaries, a dominant fraction of which was from Σ3 ( 64 pct), the latter with very low deviation from its theoretical misorientation. The application of hot rolling also resulted in a very low fraction of Σ1 ( 1 pct) boundaries, as desired. The process also leads to so-called "triple junction engineering" with the generation of special triple junctions, which are very effective in disrupting the connectivity of the random grain boundary network.

  14. Random Forest-Based Recognition of Isolated Sign Language Subwords Using Data from Accelerometers and Surface Electromyographic Sensors.

    Science.gov (United States)

    Su, Ruiliang; Chen, Xiang; Cao, Shuai; Zhang, Xu

    2016-01-14

    Sign language recognition (SLR) has been widely used for communication amongst the hearing-impaired and non-verbal community. This paper proposes an accurate and robust SLR framework using an improved decision tree as the base classifier of random forests. This framework was used to recognize Chinese sign language subwords using recordings from a pair of portable devices worn on both arms consisting of accelerometers (ACC) and surface electromyography (sEMG) sensors. The experimental results demonstrated the validity of the proposed random forest-based method for recognition of Chinese sign language (CSL) subwords. With the proposed method, 98.25% average accuracy was obtained for the classification of a list of 121 frequently used CSL subwords. Moreover, the random forests method demonstrated a superior performance in resisting the impact of bad training samples. When the proportion of bad samples in the training set reached 50%, the recognition error rate of the random forest-based method was only 10.67%, while that of a single decision tree adopted in our previous work was almost 27.5%. Our study offers a practical way of realizing a robust and wearable EMG-ACC-based SLR systems.

  15. Spectrogram analysis of complete dentures with different thickness and palatal rugae materials on speech production.

    Science.gov (United States)

    Zaki Mahross, Hamada; Baroudi, Kusai

    2015-01-01

    Objective. To investigate the influence of reproduction of different thickness and palatal rugae materials on complete dentures speech using Computerized Speech Lab (CSL) (spectrogram). Materials and Methods. Three completely edentulous male patients (aged 50-60 years) were selected for reading a paragraph. Twelve upper dentures were constructed, four for each patient. The patients' speech groups were divided into five groups, Group I: patients without dentures; Group II: patients rehabilitated with conventional acrylic dentures; Group III: patients with conventional acrylic dentures with rugae reproduction; Group IV: patients with dentures with metallic framework of minimal thickness and direct ragged metallic palatal surface at rugae area; Group V: patients with dentures with palatal rugae constructed from resilient acrylic resin material with thickness less than conventional denture. Speech samples were recorded after insertion of each denture for groups using Computerized Speech Lab (CSL) (spectrogram). The sounds selected were lingopalatal /s/z/sh/t/d/ and /l/. Results. Group III produced high mean significant difference with /sh/t/ sound. For Group IV, the difference was noticed with /s/z/sh/t/ and /d/ sounds, while for Group V the difference was shown with /z/l/ sound (P rugae area in complete denture because the phonetic quality of complete denture with rugae is superior to the conventional denture.

  16. Spectrogram Analysis of Complete Dentures with Different Thickness and Palatal Rugae Materials on Speech Production

    Directory of Open Access Journals (Sweden)

    Hamada Zaki Mahross

    2015-01-01

    Full Text Available Objective. To investigate the influence of reproduction of different thickness and palatal rugae materials on complete dentures speech using Computerized Speech Lab (CSL (spectrogram. Materials and Methods. Three completely edentulous male patients (aged 50–60 years were selected for reading a paragraph. Twelve upper dentures were constructed, four for each patient. The patients’ speech groups were divided into five groups, Group I: patients without dentures; Group II: patients rehabilitated with conventional acrylic dentures; Group III: patients with conventional acrylic dentures with rugae reproduction; Group IV: patients with dentures with metallic framework of minimal thickness and direct ragged metallic palatal surface at rugae area; Group V: patients with dentures with palatal rugae constructed from resilient acrylic resin material with thickness less than conventional denture. Speech samples were recorded after insertion of each denture for groups using Computerized Speech Lab (CSL (spectrogram. The sounds selected were lingopalatal /s/z/sh/t/d/ and /l/. Results. Group III produced high mean significant difference with /sh/t/ sound. For Group IV, the difference was noticed with /s/z/sh/t/ and /d/ sounds, while for Group V the difference was shown with /z/l/ sound (P<0.05. Conclusion. It is recommended to reproduce the rugae area in complete denture because the phonetic quality of complete denture with rugae is superior to the conventional denture.

  17. Implementation of a biotechnological process for vat dyeing with woad.

    Science.gov (United States)

    Osimani, Andrea; Aquilanti, Lucia; Baldini, Gessica; Silvestri, Gloria; Butta, Alessandro; Clementi, Francesca

    2012-09-01

    The traditional process for vat dyeing with woad (Isatis tinctoria L.) basically relies on microbial reduction of indigo to its soluble form, leucoindigo, through a complex fermentative process. In the 19th century, cultivation of woad went into decline and use of synthetic indigo dye and chemical reduction agents was established, with a consequent negative impact on the environment due to the release of polluting wastewaters by the synthetic dyeing industry. Recently, the ever-growing demand for environmentally friendly dyeing technologies has led to renewed interest in ecological textile traditions. In this context, this study aims at developing an environmentally friendly biotechnological process for vat dyeing with woad to replace use of polluting chemical reduction agents. Two simple broth media, containing yeast extract or corn steep liquor (CSL), were comparatively evaluated for their capacity to sustain the growth and reducing activity of the strain Clostridium isatidis DSM 15098(T). Subsequently, the dyeing capacity of the CSL medium added with 140 g L⁻¹ of woad powder, providing 2.4 g L⁻¹ of indigo dye, was evaluated after fermentation in laboratory bioreactors under anaerobic or microaerophilic conditions. In all fermentations, a sufficiently negative oxidation/reduction potential for reduction of indigo was reached as early as 24 h and maintained up to the end of the monitoring period. However, clearly faster indigo dye reduction was seen in the broth cultures fermented under strict anaerobiosis, thus suggesting the suitability of the N₂ flushing strategy for enhancement of bacterial-driven indigo reduction.

  18. Dynamical Time-Reversal Symmetry Breaking and Photo-Induced Chiral Spin Liquid in Frustrated Mott Insulators

    Science.gov (United States)

    Claassen, Martin; Jiang, Hong-Chen; Moritz, Brian; Devereaux, Thomas

    Spurred by recent progress in melting, enhancement and induction of electronic order out of equilibrium, a tantalizing prospect concerns instead accessing transient Floquet steady states via broad pump pulses, to manipulate band topology and affect electronic transport. Here, we extend these ideas to strongly-correlated systems and show that pumping frustrated Mott insulators with circularly-polarized light can drive the effective spin system across a phase transition to a chiral spin liquid (CSL). Starting from a Kagome Hubbard model deep in the Mott phase, circular polarization promotes a scalar spin chirality Si . (Sj ×Sk) term directly to the Hamiltonian level, dynamically breaking time-reversal while preserving SU(2) spin symmetry. We find that the transient physics is well-captured by an effective Floquet spin model, fingerprint its phase diagram, and find a stable photo-induced CSL in close proximity to the equilibrium state. The results presented suggest a new avenue of employing dynamical symmetry breaking to engineer quantum spin liquids and access elusive phase transitions that are not readily accessible in equilibrium.

  19. Statistical evaluation and modeling of cheap substrate-based cultivation medium of Chlorella vulgaris to enhance microalgae lipid as new potential feedstock for biolubricant.

    Science.gov (United States)

    Mohammad Mirzaie, M A; Kalbasi, M; Mousavi, S M; Ghobadian, B

    2016-05-18

    Chlorella vulgaris (C. vulgaris) microalga was investigated as a new potential feedstock for the production of biodegradable lubricant. In order to enhance microalgae lipid for biolubricant production, mixotrophic growth of C. vulgaris was optimized using statistical analysis of Plackett-Burman (P-B) and response surface methodology (RSM). A cheap substrate-based medium of molasses and corn steep liquor (CSL) was used instead of expensive mineral salts to reduce the total cost of microalgae production. The effects of molasses and CSL concentration (cheap substrates) and light intensity on the growth of microalgae and their lipid content were analyzed and modeled. Designed models by RSM showed good compatibility with a 95% confidence level when compared to the cultivation system. According to the models, optimal cultivation conditions were obtained with biomass productivity of 0.123 g L(-1) day(-1) and lipid dry weight of 0.64 g L(-1) as 35% of dry weight of C. vulgaris. The extracted microalgae lipid presented useful fatty acid for biolubricant production with viscosities of 42.00 cSt at 40°C and 8.500 cSt at 100°C, viscosity index of 185, flash point of 185°C, and pour point of -6°C. These properties showed that microalgae lipid could be used as potential feedstock for biolubricant production.

  20. Comparative Studies of the Venom of a New Taipan Species, Oxyuranus temporalis, with Other Members of Its Genus

    Directory of Open Access Journals (Sweden)

    Carmel M. Barber

    2014-07-01

    Full Text Available Taipans are highly venomous Australo-Papuan elapids. A new species of taipan, the Western Desert Taipan (Oxyuranus temporalis, has been discovered with two specimens housed in captivity at the Adelaide Zoo. This study is the first investigation of O. temporalis venom and seeks to characterise and compare the neurotoxicity, lethality and biochemical properties of O. temporalis venom with other taipan venoms. Analysis of O. temporalis venom using size-exclusion and reverse-phase HPLC indicated a markedly simplified “profile” compared to other taipan venoms. SDS-PAGE and agarose gel electrophoresis analysis also indicated a relatively simple composition. Murine LD50 studies showed that O. temporalis venom is less lethal than O. microlepidotus venom. Venoms were tested in vitro, using the chick biventer cervicis nerve-muscle preparation. Based on t90 values, O. temporalis venom is highly neurotoxic abolishing indirect twitches far more rapidly than other taipan venoms. O. temporalis venom also abolished responses to exogenous acetylcholine and carbachol, indicating the presence of postsynaptic neurotoxins. Prior administration of CSL Taipan antivenom (CSL Limited neutralised the inhibitory effects of all taipan venoms. The results of this study suggest that the venom of the O. temporalis is highly neurotoxic in vitro and may contain procoagulant toxins, making this snake potentially dangerous to humans.

  1. (1,3;1,4)-β-Glucan Biosynthesis by the CSLF6 Enzyme: Position and Flexibility of Catalytic Residues Influence Product Fine Structure.

    Science.gov (United States)

    Dimitroff, George; Little, Alan; Lahnstein, Jelle; Schwerdt, Julian G; Srivastava, Vaibhav; Bulone, Vincent; Burton, Rachel A; Fincher, Geoffrey B

    2016-04-05

    Cellulose synthase-like F6 (CslF6) genes encode polysaccharide synthases responsible for (1,3;1,4)-β-glucan biosynthesis in cereal grains. However, it is not clear how both (1,3)- and (1,4)-linkages are incorporated into a single polysaccharide chain and how the frequency and arrangement of the two linkage types that define the fine structure of the polysaccharide are controlled. Through transient expression in Nicotiana benthamiana leaves, two CSLF6 orthologs from different cereal species were shown to mediate the synthesis of (1,3;1,4)-β-glucans with very different fine structures. Chimeric cDNA constructs with interchanged sections of the barley and sorghum CslF6 genes were developed to identify regions of the synthase enzyme responsible for these differences. A single amino acid residue upstream of the TED motif in the catalytic region was shown to dramatically change the fine structure of the polysaccharide produced. The structural basis of this effect can be rationalized by reference to a homology model of the enzyme and appears to be related to the position and flexibility of the TED motif in the active site of the enzyme. The region and amino acid residue identified provide opportunities to manipulate the solubility of (1,3;1,4)-β-glucan in grains and vegetative tissues of the grasses and, in particular, to enhance the solubility of dietary fibers that are beneficial to human health.

  2. Continuous syngas fermentation for the production of ethanol, n-propanol and n-butanol.

    Science.gov (United States)

    Liu, Kan; Atiyeh, Hasan K; Stevenson, Bradley S; Tanner, Ralph S; Wilkins, Mark R; Huhnke, Raymond L

    2014-01-01

    Syngas fermentation to fuels is a technology on the verge of commercialization. Low cost of fermentation medium is important for process feasibility. The use of corn steep liquor (CSL) instead of yeast extract (YE) in Alkalibaculum bacchi strain CP15 bottle fermentations reduced the medium cost by 27% and produced 78% more ethanol. When continuous fermentation was performed in a 7-L fermentor, 6g/L ethanol was obtained in the YE and YE-free media. When CSL medium was used in continuous fermentation, the maximum produced concentrations of ethanol, n-propanol and n-butanol were 8 g/L, 6 g/L and 1 g/L, respectively. n-Propanol and n-butanol were not typical products of strain CP15. A 16S rRNA gene-based survey revealed a mixed culture in the fermentor dominated by A. bacchi strain CP15 (56%) and Clostridium propionicum (34%). The mixed culture presents an opportunity for higher alcohols production from syngas. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. SILICON CARBIDE GRAIN BOUNDARY DISTRIBUTIONS, IRRADIATION CONDITIONS, AND SILVER RETENTION IN IRRADIATED AGR-1 TRISO FUEL PARTICLES

    Energy Technology Data Exchange (ETDEWEB)

    Lillo, T. M.; Rooyen, I. J.; Aguiar, J. A.

    2016-11-01

    Precession electron diffraction in the transmission electron microscope was used to map grain orientation and ultimately determine grain boundary misorientation angle distributions, relative fractions of grain boundary types (random high angle, low angle or coincident site lattice (CSL)-related boundaries) and the distributions of CSL-related grain boundaries in the SiC layer of irradiated TRISO-coated fuel particles. Two particles from the AGR-1 experiment exhibiting high Ag-110m retention (>80%) were compared to a particle exhibiting low Ag-110m retention (<19%). Irradiated particles with high Ag-110m retention exhibited a lower fraction of random, high angle grain boundaries compared to the low Ag-110m retention particle. An inverse relationship between the random, high angle grain boundary fraction and Ag-110m retention is found and is consistent with grain boundary percolation theory. Also, comparison of the grain boundary distributions with previously reported unirradiated grain boundary distributions, based on SEM-based EBSD for similarly fabricated particles, showed only small differences, i.e. a greater low angle grain boundary fraction in unirradiated SiC. It was, thus, concluded that SiC layers with grain boundary distributions susceptible to Ag-110m release were present prior to irradiation. Finally, irradiation parameters were found to have little effect on the association of fission product precipitates with specific grain boundary types.

  4. Assessment of treatment efficacy and sebosuppressive effect of fractional radiofrequency microneedle on acne vulgaris.

    Science.gov (United States)

    Lee, Kyung Real; Lee, Eo Gin; Lee, Hee Jung; Yoon, Moon Soo

    2013-12-01

    A minimally invasive fractional radiofrequency microneedle (FRM) device has been used in skin rejuvenation and acne scars, and a recent pilot study demonstrated the positive therapeutic effect on acne. We evaluated the efficacy of FRM device for acne vulgaris in Asians and conducted objective measurement to assess its effect on sebum production. Twenty Korean patients with acne vulgaris received a single full-face FRM treatment. Outcome assessments included standardized photography, physician's global assessment, patient's satisfaction scores, acne lesion count, and objective measurements of casual sebum level (CSL) and sebum excretion rate (SER). They were evaluated at baseline and 2, 4, 8 weeks after the treatment. After a single FRM treatment, the CSL and the SER showed 30-60% and 70-80% reduction, respectively, at week 2 (P acne severity and acne lesion count also revealed clinical improvement with maximum efficacy at week 2, but returned to the baseline in most patients by week 8. Patients' satisfaction scores (0-4) were above 2 on average, and adverse effects were minimal. This prospective study demonstrated the sebosuppressive effect from a single FRM treatment, but its therapeutic efficacy in acne requires further evaluation. © 2013 Wiley Periodicals, Inc.

  5. Grain boundary character distributions of coincidence site lattice boundaries in WC-Co composites with different WC grain sizes

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Xiaokun, E-mail: yuanxiaokun@bjut.edu.cn

    2013-12-05

    Highlights: •GBCDs of two kinds of CSL boundaries in cemented carbides are examined. •Carbide mean grain size is determinant in controlling the populations of CSL boundaries. •Rapid decrease of sigma2 boundaries occurs at higher speed than the coarsening of carbide grains. -- Abstract: The grain boundary character distributions of sigma2 and sigma13 boundaries were investigated in cemented carbide samples with different carbide grain sizes. Samples were prepared with average carbide grain sizes of about 0.5 μm, 1 μm and 2 μm, respectively. The electron backscattered diffraction measurements show that with the increase of the carbide grain size, populations of both sigma2 and sigma13 boundaries decrease; in the meantime, the sigma2 twist and sigma13 twist boundaries keep as the most common boundary types. The results suggest that the carbide grain size could be determinant in controlling the populations of coincidence site lattice boundaries in WC-Co composites.

  6. Utilizacao de residuos agroindustriais em processo biotecnologico para producao de ƒÒ-galactosidase de Kluyveromyces marxianus CCT 7082 = Use of agroindustrial residues in biotechnological process by betagalactosidase production from Kluyveromyces marxianus CCT 7082

    Directory of Open Access Journals (Sweden)

    Ana Paula Manera

    2011-04-01

    Full Text Available O objetivo deste trabalho foi avaliar a composicao do meio de cultura para a producao da enzima ƒÒ-galactosidase de Kluyveromyces marxianus CCT 7082 utilizando a tecnica de delineamento experimental. A producao da enzima foi realizada em meio composto por soro de queijo, agua de maceracao de milho (AMM e hidrolisado de levedura Prodex-lacR e sais. Foi realizado um planejamento experimental fracionario (25-1 para determinar as variaveis significativas na producao da enzima. Foram testadas diferentes concentracoes de lactose presente no soro de queijo (10 a 70 g L-1, AMM (10 a 100 g L-1, Prodex-lac (4 a 20 g L-1, (NH42SO4 (0 a 10 g L-1 e o pH (5 a 7. As variaveis concentracao de lactose, AMM e o pH apresentaram efeito estatisticamente significativo na atividade enzimatica dentro das faixas estudadas, sendo estas variaveis empregadas num delineamento composto central rotacional para otimizar a producao da enzima. As faixas testadas foram: concentracao de lactose de 40 a 100 g L-1, AMM de 10 a 120 g L-1 e pH de 3,5 a 6,5. As condicoes que resultaram em maior atividade enzimatica (1400 U g-1 foram 70 g L-1 de lactose, 65 g L-1 de AMM, 4 g L-1 de Prodex-lac e pH 5, obtendo uma produtividade de 61 U L-1 h-1. The objective of this work was to evaluate the composition of the culture medium for the production of the enzyme ƒÒ-galactosidase from Kluyveromyces marxianus CCT 7082 using an experimental design. Enzyme production was carried out in a medium consisting of cheese whey, cornsteep liquor (CSL and Prodex-lacR yeast hydrolyzate. A factorial fractional design (25-1 was performed to determine the significant variables in the production of the enzyme. Different concentrations of lactose present in whey (10-70 g L-1, CSL (10-100 g L-1, Prodex-lac (40- 20 g L-1, (NH42SO4 (0-10 g L-1 and pH (5-7 were tested. Lactose concentration, CSL and pH were the variables that showed a statistically significant effect on enzyme activity withinthe ranges studied

  7. Bimolecular encounters and re-encounters (cage effect) of a spin-labeled analogue of cholestane in a series of n-alkanes: effect of anisotropic exchange integral.

    Science.gov (United States)

    Vandenberg, Andrew D; Bales, Barney L; Salikhov, K M; Peric, Miroslav

    2012-12-27

    Electron paramagnetic resonance (EPR) spectra of the nitroxide spin probe 3β-doxyl-5α-cholestane (CSL) are studied as functions of the molar concentration, c, and the temperature, T, in a series of n-alkanes. The results are compared with a similar study of a much smaller spin probe, perdeuterated 2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl (pDT). The Heisenberg spin exchange (HSE) rate constants, K(ex), of CSL are similar in hexane, octane, and decane and are about one-half of those for pDT in the same solvents. They are also about one-half of the Stokes-Einstein-Perrin prediction. This reduction in HSE efficiency is attributed to an effective steric factor, f(eff), which was evaluated by comparing the results with the Stokes-Einstein-Perrin prediction or with pDT, and it is equal to 0.49 ± 0.03, independent of temperature. The unpaired spin density in CSL is localized near one end of the long molecule, so the exchange integral, J, leading to HSE, is expected to be large in some collisions and small in others; thus, J is modeled by an ideal distribution of values of J = J(0) with probability f and J = 0 with probability (1 - f). Because of rotational and translation diffusion during contact and between re-encounters of the probe, the effective steric factor is predicted to be f(eff) = f(1/2). Estimating the fraction of the surface of CSL with rich spin density yields a theoretical estimate of f(eff) = 0.59 ± 0.08, in satisfactory agreement with experiment. HSE is well described by simple hydrodynamic theory, with only a small dependence on solvent-probe relative sizes at the same value of T/η, where η is the viscosity of the solvent. This result is probably due to a fortuitous interplay between long- and short-range effects that describe diffusion processes over relatively large distances. In contrast, dipole-dipole interactions (DD) as measured by the line broadening, B(dip), and the mean time between re-encounters within the cage, τ(RE), vary significantly

  8. Data management of clinical trials during an outbreak of Ebola virus disease.

    Science.gov (United States)

    Hossmann, Stefanie; Haynes, Alan G; Spoerri, Adrian; Diatta, Ibrahima Dina; Aboubacar, Barry; Egger, Matthias; Rintelen, Felix; Trelle, Sven

    2017-10-23

    Clinical trial data management (DM) conducted during outbreaks like that of Ebola virus disease (EVD) in West Africa, 2014-2016, has to adapt to specific, unique circumstances. CTU Bern was asked to set up a safe data capture/management system that could be launched within a few weeks and cover two different vaccine trials. This article describes some of the challenges we faced and our solutions during the two different trials. Setting up a DM system was split into four phases/tasks: (1) quick set-up of the (electronic) data capture system (EDC) and mobile infrastructure in Bern, (2) moving the EDC and infrastructure to Conakry, Guinea and implementation of a local data management centre (DMC), (3) running the DMC, and (4) data cleaning. The DMC had to meet the following criteria: (1) quick implementation, (2) efficient maintenance and handling of data, and (3) procedures to guarantee data quality. The EDC (REDCap) was setup as a local area network. In order to ensure high data quality, double data entry, and then review of inconsistencies and offline plausibility checks were implemented. From the start of CTU Bern's involvement to the productive EDC took 11 weeks. It was necessary to adapt processes for dealing with data continuously throughout the trial conduct phase. The data management team processed 171,794 case report form pages from a total of 14,203 participants in the period between March and December 2015. Data management is a key task supporting trial conduct. For trials in emergency situations, many of our approaches are suitable, but we also provide a list of aspects that might be done differently. Copyright © 2017. Published by Elsevier Ltd.

  9. The Conversion of a Peer Teaching Course in the Puncture of Peripheral Veins for Medical Students into an Interprofessional Course

    Directory of Open Access Journals (Sweden)

    Brem, Beate Gabriele

    2016-04-01

    Full Text Available Objective: There is a great interest on both a national and international level in promoting cooperation between different occupational groups within the healthcare professions through interprofessional education (IPE , , . Within this project, a peer teaching course on the puncture of peripheral veins was therefore converted from a course for medical students into an IPE learning unit. Students from different occupational groups were to learn within the context of this course, according to the definition from the World Health Organisation (WHO, with and from each other . Project description: This course constituted a small group class in the peer teaching format. The didactic principle was based on the idea that the students were to practice the respective practical skills in pairs and give each other reciprocal feedback. Together with the Department for Health at the Bern University of Applied Sciences (BUAS and the Bern Center of Higher Education of Nusing (BCHEN, the course, which was conducted by the Institute of Medical Education at the University of Bern (IME, was converted into a voluntary IPE pilot project. Students from all three institutions were represented in terms of participants as well as tutors. Results: The course was evaluated very positively by participants, peer tutors and the participating institutions. By means of an OSCE, it could be proven that the course content had been successfully imparted. On the basis of these results, it was determined that the course should be compulsory in the future for students at all three institutions. Discussion: The evaluation results show the successful conversion of the course into an IPE format within the context of the pilot project. The interactive format of the course created the prerequisite that the students from different professional groups learned with and from each other in actuality, and did not just study the same objectives at the same time as with multiprofessional learning

  10. Flutuação sazonal de Dermatobia hominis em peles bovinas oriundas de matadouro

    Directory of Open Access Journals (Sweden)

    Brito Luciana Gatto

    2000-01-01

    Full Text Available Realizou-se o estudo do efeito da temperatura, precipitação pluviométrica e da umidade relativa sobre a flutuação sazonal de larvas de Dermatobia hominis em 5.142 peles de bovinos. As peles foram obtidas junto a um matadouro localizado no município de Piraí, estado do Rio de Janeiro, Brasil, durante o período de novembro de 1995 a outubro de 1997. Os maiores picos de peles parasitadas por berne foram observados em novembro de 1995 e dezembro de 1996. Picos menores de infestação foram observados nos meses de março e maio de 1996 e março de 1997, quando também foram observadas altas porcentagens de peles infestadas. O aumento na porcentagem de peles parasitadas acompanhou o aumento da temperatura média mensal, sendo que temperaturas iguais ou maiores que 25ºC se mostraram benéficas ao aumento na porcentagem de peles parasitadas, assim como a precipitação pluviométrica, onde observou-se que períodos de chuvas mensais acima de 200 mm³ favoreceram ao aumento da porcentagem de peles parasitadas. As menores porcentagens de peles parasitadas por berne foram observadas durante o período de junho a outubro de 1996 e de 1997, quando verificou-se temperaturas médias mensais variando entre 21ºC e 22,5ºC, sendo que estas não se mostraram favoráveis ao aumento na porcentagem de peles parasitadas, assim como, precipitações pluviométricas mensais menores que 50 mm³. Das 5.142 peles examinadas, 2.710 (52,7% encontravam-se parasitadas pelo berne.

  11. Advantages and limits to the fermentation of easily-degradable industrial and food wastes in sewage treatment works; Vorteile und Grenzen der Vergaerung von leicht abbaubaren Industrie- und Lebensmittelabfaellen in Abwasserreinigungsanlagen. Vergleich zu landwirtschaftlichen Anlagen - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, N.; Wellinger, A. [Nova Energie GmbH, Aadorf (Switzerland); Bachmann, N. [EREP SA, Aclens (Switzerland)

    2009-12-15

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at the advantages and limits that apply to the fermentation of industrial and food wastes in sewage treatment facilities in comparison to agricultural installations. For this ecological review, a material-flow analysis was made which permitted the nutrient loss to be quantified. The report presents data on the energy and carbon dioxide balances for the method and also looks at the method from an economical point of view. Co-fermentation in the wastewater treatment plant in Berne, Switzerland, and in agricultural plant are examined.

  12. A Critical Analysis of Globalilzation in the Context of Africa Underdevelopment

    Directory of Open Access Journals (Sweden)

    Mohammed O. Lawal

    2013-07-01

    While globalization is considered as a pride to the West and Europe, Africa is still being regarded as localized. The paper goes filrther to address the imbalance and disparity that have existed bern.'een the developed and underdeveloped countries in the areas of electronic, commerce, Information Communication Technology (ICT among others. Also, the opportunities and challenges posed by globalization are critically focused. The paper identifies the Aji-ican problems of underdevelopment and proposes strategies by which these problems could be solved so that Africa would be able to 'catch up' in the globalization process.

  13. Extracellular Adenosine Triphosphate Associated with Amphibian Erythrocytes: Inhibition of ATP Release by Anion Channel Blockers.

    Science.gov (United States)

    1986-01-01

    cells is diminished (406,432), a finding consistent with the decreased deformability and increased fragility of erythrocytes in Duchenne patients (170...Berne, T.W. Rall and R. Rubio, eds. The Hague: Martinus Nijhoff. pp. 179-201, 1983. - 347. Plagemann, P.G.W., Wohlhueter, R.M. and Erbe , J. Nucleoside...in Duchenne and myotonic muscular dystrophy. Nature 268:55-56, 1977. I5 . e. -. 𔃺 6 246 407. Sparks, Jr., H.V., and Belloni, F.L. The peripheral

  14. Molecular dynamics algorithms for quantum Monte Carlo methods

    Science.gov (United States)

    Miura, Shinichi

    2009-11-01

    In the present Letter, novel molecular dynamics methods compatible with corresponding quantum Monte Carlo methods are developed. One is a variational molecular dynamics method that is a molecular dynamics analog of quantum variational Monte Carlo method. The other is a variational path integral molecular dynamics method, which is based on the path integral molecular dynamics method for finite temperature systems by Tuckerman et al. [M. Tuckerman, B.J. Berne, G.J. Martyna, M.L. Klein, J. Chem. Phys. 99 (1993) 2796]. These methods are applied to model systems including the liquid helium-4, demonstrated to work satisfactorily for the tested ground state calculations.

  15. The 2016 Frontiers in Medicinal Chemistry Conference in Bonn.

    Science.gov (United States)

    Müller, Christa E; Thimm, Dominik; Baringhaus, Karl-Heinz

    2017-01-05

    Pushing the frontiers of medicinal chemistry: Christa Müller, Dominik Thimm, and Karl-Heinz Baringhaus look back at the events of the 2016 Frontiers in Medicinal Chemistry (FiMC) Conference held in Bonn, Germany. The report highlights the themes & talks in the annual conference hosted by the Joint Division of Medicinal Chemistry of the German Pharmaceutical Society (DPhG) and German Chemical Society (GDCh). It is also an invitation to the 2017 conference in Bern, Switzerland this February 12-15. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Method for the appraisal and classification of the suitability for use of watercourses - Appendices; Methodik zur Bewertung und Klassierung der Nutzungseignung von Fliessgewaesserstrecken. Grundlagen fuer die raeumliche Prioritaetensetzung bei der Wasserkraftnutzung und dem Schutz von Gewaessern - Annex 2: Beruecksichtigung der Schutz- und Nutzungsinteressen bei der Wasserkraftnutzung (ohne Karten)

    Energy Technology Data Exchange (ETDEWEB)

    Wehse, H.

    2009-10-15

    These appendices to final report for the Swiss Federal Office of Energy (SFOE) that discusses the fundamentals for setting priorities for the use of hydropower and the protection of streams and rivers present a rich bibliography on the subject and a documentation on current projects. Also a comprehensive list of criteria and a selection of particularly relevant criteria is presented. Also, the 'Master-plan river ecology' for the Canton of Berne, Switzerland, is included. A further appendix discusses the methodology used for the definition of potential for improvement as far as river morphology is concerned.

  17. Teatrimaailm / Mari Kolle, Katrin Talts

    Index Scriptorium Estoniae

    Kolle, Mari

    2005-01-01

    23. märtsil avatakse unikaalne interneti-projekt "Cultu.Ru!" ; Londoni Criterion Theatre'is etendub "Amajuba. Me tõuseme lendu nagu tuvid", mida esitavad Lõuna-Aafrika viis näitlejat, kes räägivad oma elust ; ITI on tänavu ülemaailmse teatripäeva pühendanud naistele, korraldades rahvusvahelise kübernäituse "Naised teatris", mis esitleb eri maade teatripraktikuid : naislavastajaid, näitekirjanikke ja näitlejannasid XX sajandi II poolel ; Pariisis tegutsevast Päikeseteatrist ning teatri asutajast ja juhist A. Mnouchkine'ist

  18. The Necessity to collectivize copyright - and dangers thereof

    DEFF Research Database (Denmark)

    Schovsbo, Jens Hemmingsen

    This article describes and discusses the effects of collective rights administration of (individual) copyright. It points out that collectivization is driven either by en economic argument relating to the reduction of transaction costs or a cultural one relating to the protection of authors....... It then claims that collectivization has the potential to affect copyright as it is perceived in the Berne Convention and in traditional copyright legislation fundamentally. The effects include a basic shift in copyright from a system based on property rules to a system based also on liability rules. The article...

  19. Introduction: Information and Musings

    Science.gov (United States)

    Shifman, M.

    The following sections are included: * Victor Frenkel * Background * The Accused * Alexander Leipunsky * Alexander Weissberg * Holodomor * The beginning of the Great Purge * Other foreigners at UPTI * The Ruhemanns * Tisza * Lange * Weisselberg * A detective story * Stalin's order * Yuri Raniuk * Giovanna Fjelstad * Giovanna's story * First time in the USSR * Fisl's humor * Houtermans and Pomeranchuk * Choices to make * Closing gaps * Houtermans and the Communist Party of Germany * Houtermans and von Ardenne * Houtermans' trip to Russia in 1941 * Why Houtermans had to flee from Berlin in 1945 * Houtermans in Göttingen in the 1940's * Denazification * Moving to Bern * Yuri Golfand, the discoverer of supersymmetry * Bolotovsky's and Eskin's essays * Moisei Koretz * FIAN * Additional recommended literature * References

  20. Project Inner Brick - Colorful Plastic Bricks in Psychotherapy - An Introduction to Methodology

    Directory of Open Access Journals (Sweden)

    Neidert László

    2015-06-01

    Full Text Available PIB is a research project pertaining to the psychotherapeutic potential of Lego bricks. This is based on Lego Group’s own method called Lego Seriousplay and Eric Berne's transactional analysis as a theoretical background. If we see it from the Lego’s aspect, our plan is a training like LSP. It is only alike because of the special application. We made a lot of modifications according to the original methodology. In this document we would like to present details of our research we have been working on for almost two years. The characteristics of our methodology will be illustrated, too.

  1. European School of High-Energy Physics, Beatenberg, Switzerland, 26 August - 8 September 2001

    CERN Multimedia

    2000-01-01

    The 2001 European School of High-Energy Physics (formerly the CERN-JINR School of Physics) will be organized jointly by the European Organization for Nuclear Research (CERN), Geneva, Switzerland and the Joint Institute for Nuclear Research (JINR), Dubna, Russia, together with the University of Bern. The basic aim of the School is to teach various aspects of high-energy physics, but especially theoretical physics, to young experimental physicists, mainly from the Member States of CERN and of JINR. The Schools of Physics are designed to give a survey of up-to-date information, rather than to be a training course.

  2. Gluon scattering amplitudes at strong coupling

    Energy Technology Data Exchange (ETDEWEB)

    Alday, Luis F. [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, 3508 TD Utrecht (Netherlands); Maldacena, Juan [School of Natural Sciences, Institute for Advanced Study, Princeton, NJ 08540 (United States)

    2007-06-15

    We describe how to compute planar gluon scattering amplitudes at strong coupling in N = 4 super Yang Mills by using the gauge/string duality. The computation boils down to finding a certain classical string configuration whose boundary conditions are determined by the gluon momenta. The results are infrared divergent. We introduce the gravity version of dimensional regularization to define finite quantities. The leading and subleading IR divergencies are characterized by two functions of the coupling that we compute at strong coupling. We compute also the full finite form for the four point amplitude and we find agreement with a recent ansatz by Bern, Dixon and Smirnov.

  3. Influência da posição das sementes no fruto do cacaueiro sôbre a germinação e desenvolvimento das mudas Influence of seed location in the cocoa fruit on germination and seedling growth

    Directory of Open Access Journals (Sweden)

    Mário Cardoso

    1963-01-01

    Full Text Available Foram plantadas separadamente, para comparação, amostras de sementes oriundas da ponta, do centro e da base de frutos de cacaueiro. Não foram notadas diferenças, quer na germinação das sementes, quer no desenvolvimento das mudas, em duas variedades estudadas.Seed samples from the top, center, and bottom of the cocoa fruit (Theobroma leiocarpa Bern. were planted separately for comparison. No difference in germination of the seeds or growth of the seedlings for the three types of samples was noticed.

  4. The IPBES conceptual framework — connecting nature and people

    CSIR Research Space (South Africa)

    Diaz, S

    2015-06-01

    Full Text Available of the Convention on Biological Diversity (CBD), 413 Saint- Jacques Street, Montreal, QC H2Y 1N9, Canada 17Mahatma Gandhi Institute of Education on Peace and Sustainable Development, New Delhi, India 18 Institute of Plant Sciences, University of Bern, Switzerland 19... nature and people in IPBES Dı´az et al. 5Figure 1anthropocentric instrumental and relational values (see Values section below). 2. ‘Anthropogenic assets’ refers to built infrastructure, health facilities, knowledge (including ILK and technical...

  5. A lira assassina de Orfeu (Bernardo Santareno e os intertextos de \\'O Inferno\\')

    OpenAIRE

    Fernanda Verdasca Botton

    2008-01-01

    Para compor o canto de morte do serial-killer Orfeu wilson, o dramaturgo português Bernardo Santareno traz à peça teatral O inferno uma discussão intertextual a tratar da origem dos indivíduos criminosos. Essa tese tem como objetivo desvendar os intertextos realizados por Santareno e estudar o pensamento de um psiquiatra dramaturgo que tenta compreender a mente criminosa In order to compose the death song intoned by the serial killer Orfeu Wilson, the portuguese play-wright Bern...

  6. A Molecular View of Liquid Crystalline Elastomers and Gels

    Science.gov (United States)

    de Pablo, Juan

    2011-03-01

    A combination of Monte Carlo and molecular dynamics simulations is used to examine the order-disorder transitions that arise in model liquid crystalline elastomers and colloidal gels as a function of concentration and strain, respectively. Two models are considered. In the first, a lattice model is used to represent a colloidal gel of nematogens and nanoparticles. In the second, a cross-linked elastomer of Gay-Berne mesogens is adopted to examine the order-disroder transition that arises as a function of strain. The results of simulations are compared to those of recent experiments for these two classes of systems.

  7. The Lazarus effect

    CERN Multimedia

    Laurent Guiraud

    1998-01-01

    Members of the RD39 collaboration stage a demonstration of the Lazarus effect in the CERN cryolab. At the LHC experiments, the front-line inner detectors - trackers - will be traversed by a mammoth thousand million million passing particles per square centimetre over the lifetimes of the experiments. After long exposure to passing particles, defects appear in the silicon and the signal is destroyed. A group of physicists at Bern University have found that at temperatures below 100 K, dead detectors apparently come back to life. They're calling their discovery the Lazarus effect after the Biblical character raised from the dead by Jesus after he had been entombed for four days.

  8. Management recommendations and performances for more effective conservation of the Spanish imperial eagles (Aquila adalberti Brehm, 1861) habitat and population.

    OpenAIRE

    Grande Vega, María; Velázquez Saornil, Javier; Hernando Gallego, Ana

    2008-01-01

    The Spanish imperial eagle (Aquila Adalberti BREHM, 1861) is nowadays the predatory bird most threatened in the Iberian Peninsula, as well as one of the most threatened in the world. It is listed in several International agreements of protection (IUCN, Bern, Cites, Bonn) as well as in the annexe I of Birds Directive (79/409/CEE) which makes up the Natura 2000 network. Regarding the Spanish framework, some measures have been taking to protect the Spanish imperial eagle. It is included in the N...

  9. A common objective, a variety of paths

    International Nuclear Information System (INIS)

    2009-01-01

    High-level political, governmental and regulatory decision makers, as well as representatives of economic and social groups and implementing organisations met in Berne, Switzerland to present and to reflect on their collective experience towards meeting the challenge of implementing national disposal projects for placing radioactive waste in deep geological formations. This summary highlights the main lessons to be learnt and final recommendations to assist future developments in national radioactive waste management programmes seeking to meet both technical and social imperatives of modern society. (authors)

  10. Substrate-induced bulk alignment of liquid crystals

    DEFF Research Database (Denmark)

    Zhang, Zhengping; Chakrabarti, A.; Mouritsen, Ole G.

    1996-01-01

    The Gay-Berne model for liquid crystals in the presence of a substrate surface is studied using the hybrid Monte Carlo method. A simple non-mean-field substrate-molecule potential is proposed to describe the effects of rubbed polymer-coated substrates on the liquid crystals. Effects...... of the substrate surface on the bulk alignment of the liquid crystals are studied. It is found that the bulk pretilt angle is controlled by the surface through the orientation of the adsorbed liquid crystal monolayer. This is consistent with the results of recent experimental studies....

  11. CFD Modeling in Development of Renewable Energy Applications

    OpenAIRE

    Maher A.R. Sadiq Al-Baghdadi

    2013-01-01

    Chapter 1: A Multi-fluid Model to Simulate Heat and Mass Transfer in a PEM Fuel Cell. Torsten Berning, Madeleine Odgaard, Søren K. Kær Chapter 2: CFD Modeling of a Planar Solid Oxide Fuel Cell (SOFC) for Clean Power Generation. Meng Ni Chapter 3: Hydrodynamics and Hydropower in the New Paradigm for a Sustainable Engineering. Helena M. Ramos, Petra A. López-Jiménez Chapter 4: Opportunities for CFD in Ejector Solar Cooling. M. Dennis Chapter 5: Three Dimensional Modelling of Flow Field Around a...

  12. Visit of Her Royal Highness Princess Maha Chakri Sirindhorn, Thailand

    CERN Multimedia

    Patrice Loïez

    2000-01-01

    Her Royal Highness Princess Maha Chakri Sirindhorn of Thailand (left) visiting DELPHI with Spokesman, Tiziano Camporesi, and Prapol Assavavirulhakarn, Pattaratorn Chirapravati, Claude Détraz, CERN Director for Fixed Target andFuture Programmes and Richard Breedon, University of California. No. 05: Princess Maha Chakri Sirindhorn and Daniel Treille, former spokesman of Delphi. No. 31: in Delphi experiment. No. 35: H.E. Mr. Virasakdi Futrakul, Ambassador, Permanent Representative ofThailand, Geneva with H.E. Dr. Ronarong Nopakun, Ambassador of the Thai Embassy in Bern

  13. Precession electron diffraction for SiC grain boundary characterization in unirradiated TRISO fuel

    International Nuclear Information System (INIS)

    Lillo, T.M.; Rooyen, I.J. van; Wu, Y.Q.

    2016-01-01

    Highlights: • SiC grain orientation determined by TEM-based precession electron diffraction. • Orientation data improved with increasing TEM sample thickness. • Fraction of low angle grain boundaries lower from PED data than EBSD data. • Fractions of high angle and CSL-related boundaries similar to EBSD data. - Abstract: Precession electron diffraction (PED), a transmission electron microscopy-based technique, has been evaluated for the suitability for evaluating grain boundary character in the SiC layer of tristructural isotropic (TRISO) fuel. This work reports the effect of transmission electron microscope (TEM) lamella thickness on the quality of data and establishes a baseline comparison to SiC grain boundary characteristics, in an unirradiated TRISO particle, determined previously using a conventional electron backscatter diffraction (EBSD) scanning electron microscope (SEM)-based technique. In general, it was determined that the lamella thickness produced using the standard focused ion beam (FIB) fabrication process (∼80 nm), is sufficient to provide reliable PED measurements, although thicker lamellae (∼120 nm) were found to produce higher quality orientation data. Also, analysis of SiC grain boundary character from the TEM-based PED data showed a much lower fraction of low-angle grain boundaries compared to SEM-based EBSD data from the SiC layer of a TRISO-coated particle made using the same fabrication parameters and a SiC layer deposited at a slightly lower temperature from a surrogate TRISO particle. However, the fractions of high-angle and coincident site lattice (CSL)-related grain boundaries determined by PED are similar to those found using SEM-based EBSD. Since the grain size of the SiC layer of TRSIO fuel can be as small as 250 nm (Kirchhofer et al., 2013), depending on the fabrication parameters, and since grain boundary fission product precipitates in irradiated TRISO fuel can be nano-sized, the TEM-based PED orientation data

  14. Evidence for an association between non-syndromic cleft lip with or without cleft palate and a gene located on the long arm of chromosome 4

    Energy Technology Data Exchange (ETDEWEB)

    Healey, S.C.; Chenevix-Trench, G. [Queensland Institute of Medical Research, Brisbane (Australia); Mitchell, L.E. [Saint Louis Univ., MO (United States)

    1994-09-01

    Evidence of linkage has been reported for non-syndromic cleft lip with or without cleft palate (CL{+-}P) and two markers (D4S175 and D4S192) in the region 4q25-4q31.3. The linkage evidence comes from a single Caucasian pedigree with multiple cases of CL{+-}P in five generations. High-density pedigrees are, however, atypical of CL{+-}P and linkage evidence obtained from such a family may not be relevant to the majority of CL{+-}P families. We have, therefore, examined the association of CL{+-}P with both D4S175 and D4S192 in 95 unrelated CL{+-}P patients and 161 unselected controls. There was no evidence for an association between D4S175 and CL{+-}P in these data. There was, however, a significant association between D4S192 and CL{+-}P ({chi}{sup 2}{sub 4}=15.5,P=0.006), and the genotypic distribution was significantly heterogeneous between CL{+-}P patients and controls (P=0.025). Comparison of each of the four most common alleles (i.e A87, A89, A91 and A95), to all other alleles combined, indicated that A87 was significantly less common (OR=0.56,95% C.I. 0.34-0.90), and A95 was significantly more common (OR=1.88,95% C.I. 1.03-3.43) among the CL{+-}P patients than the controls. Although of only borderline significance, A89 also appeared to be more common among patients than controls (OR=1.43,95% C.I. 0.99-2.60). Hence, it appears that genetic variation at a CL{+-}P susceptibility locus (CSL) linked to D4S192 may be associated with both increased and decreased risk of CL{+-}P. In combination, A89 and A95 are significantly more common in CL{+-}P patients than in controls (OR=1.80;95% C.I. 1.24-2.60) and account for a risk ratio of 1.08 in the first degree relatives of CL{+-}P patients. These results provide further evidence for the presence of a CSL in the region 4q25-4q31.1, and indicate that the putative CSL is located closer to D4S192 than to D4S175.

  15. Revisiting Notechis scutatus venom: on shotgun proteomics and neutralization by the "bivalent" Sea Snake Antivenom.

    Science.gov (United States)

    Tan, Choo Hock; Tan, Kae Yi; Tan, Nget Hong

    2016-07-20

    Recent advances in proteomics enable deep profiling of the compositional details of snake venoms for improved understanding on envenomation pathophysiology and immunological neutralization. In this study, the venom of Australian tiger snake (Notechis scutatus) was trypsin-digested in solution and subjected to nano-ESI-LCMS/MS. Applying a relative quantitative proteomic approach, the findings revealed a proteome comprising 42 toxin subtypes clustered into 12 protein families. Phospholipases A2 constitute the most abundant toxins (74.5% of total venom proteins) followed by Kunitz serine protease inhibitors (6.9%), snake venom serine proteases (5.9%), alpha-neurotoxins (5.6%) and several toxins of lower abundance. The proteome correlates with N. scutatus envenoming effects including pre-synaptic and post-synaptic neurotoxicity and consumptive coagulopathy. The venom is highly lethal in mice (intravenous median lethal dose=0.09μg/g). BioCSL Sea Snake Antivenom, raised against the venoms of beaked sea snake (Hydrophis schistosus) and N. scutatus (added for enhanced immunogenicity), neutralized the lethal effect of N. scutatus venom (potency=2.95mg/ml) much more effectively than the targeted H.schistosus venom (potency=0.48mg/ml). The combined venom immunogen may have improved the neutralization against phospholipases A2 which are abundant in both venoms, but not short-neurotoxins which are predominant only in H. schistosus venom. A shotgun proteomic approach adopted in this study revealed the compositional details of the venom of common tiger snake from Australia, Notechis scutatus. The proteomic findings provided additional information on the relative abundances of toxins and the detection of proteins of minor expression unreported previously. The potent lethal effect of the venom was neutralized by bioCSL Sea Snake Antivenom, an anticipated finding due to the fact that the Sea Snake Antivenom is actually bivalent in nature, being raised against a mix of venoms of the

  16. Production of Bacterial Cellulose by Gluconacetobacter hansenii Using Corn Steep Liquor As Nutrient Sources

    Directory of Open Access Journals (Sweden)

    Andrea F. S. Costa

    2017-10-01

    Full Text Available Cellulose is mainly produced by plants, although many bacteria, especially those belonging to the genus Gluconacetobacter, produce a very peculiar form of cellulose with mechanical and structural properties that can be exploited in numerous applications. However, the production cost of bacterial cellulose (BC is very high to the use of expensive culture media, poor yields, downstream processing, and operating costs. Thus, the purpose of this work was to evaluate the use of industrial residues as nutrients for the production of BC by Gluconacetobacter hansenii UCP1619. BC pellicles were synthesized using the Hestrin–Schramm (HS medium and alternative media formulated with different carbon (sugarcane molasses and acetylated glucose and nitrogen sources [yeast extract, peptone, and corn steep liquor (CSL]. A jeans laundry was also tested. None of the tested sources (beside CSL worked as carbon and nutrient substitute. The alternative medium formulated with 1.5% glucose and 2.5% CSL led to the highest yield in terms of dry and hydrated mass. The BC mass produced in the alternative culture medium corresponded to 73% of that achieved with the HS culture medium. The BC pellicles demonstrated a high concentration of microfibrils and nanofibrils forming a homogenous, compact, and three-dimensional structure. The biopolymer produced in the alternative medium had greater thermal stability, as degradation began at 240°C, while degradation of the biopolymer produced in the HS medium began at 195°C. Both biopolymers exhibited high crystallinity. The mechanical tensile test revealed the maximum breaking strength and the elongation of the break of hydrated and dry pellicles. The dry BC film supported up to 48 MPa of the breaking strength and exhibited greater than 96.98% stiffness in comparison with the hydrated film. The dry film supported up to 48 MPa of the breaking strength and exhibited greater than 96.98% stiffness in comparison with the hydrated film

  17. Production of Bacterial Cellulose by Gluconacetobacter hansenii Using Corn Steep Liquor As Nutrient Sources

    Science.gov (United States)

    Costa, Andrea F. S.; Almeida, Fabíola C. G.; Vinhas, Glória M.; Sarubbo, Leonie A.

    2017-01-01

    Cellulose is mainly produced by plants, although many bacteria, especially those belonging to the genus Gluconacetobacter, produce a very peculiar form of cellulose with mechanical and structural properties that can be exploited in numerous applications. However, the production cost of bacterial cellulose (BC) is very high to the use of expensive culture media, poor yields, downstream processing, and operating costs. Thus, the purpose of this work was to evaluate the use of industrial residues as nutrients for the production of BC by Gluconacetobacter hansenii UCP1619. BC pellicles were synthesized using the Hestrin–Schramm (HS) medium and alternative media formulated with different carbon (sugarcane molasses and acetylated glucose) and nitrogen sources [yeast extract, peptone, and corn steep liquor (CSL)]. A jeans laundry was also tested. None of the tested sources (beside CSL) worked as carbon and nutrient substitute. The alternative medium formulated with 1.5% glucose and 2.5% CSL led to the highest yield in terms of dry and hydrated mass. The BC mass produced in the alternative culture medium corresponded to 73% of that achieved with the HS culture medium. The BC pellicles demonstrated a high concentration of microfibrils and nanofibrils forming a homogenous, compact, and three-dimensional structure. The biopolymer produced in the alternative medium had greater thermal stability, as degradation began at 240°C, while degradation of the biopolymer produced in the HS medium began at 195°C. Both biopolymers exhibited high crystallinity. The mechanical tensile test revealed the maximum breaking strength and the elongation of the break of hydrated and dry pellicles. The dry BC film supported up to 48 MPa of the breaking strength and exhibited greater than 96.98% stiffness in comparison with the hydrated film. The dry film supported up to 48 MPa of the breaking strength and exhibited greater than 96.98% stiffness in comparison with the hydrated film. The values

  18. Traumatization and chronic pain: a further model of interaction

    Directory of Open Access Journals (Sweden)

    Egloff N

    2013-11-01

    Full Text Available Niklaus Egloff,1 Anna Hirschi,2 Roland von Känel1 1Department of General Internal Medicine, Division of Psychosomatic Medicine, Inselspital, University Hospital, Bern, Switzerland; 2Outpatient Clinic for Victims of Torture and War, Swiss Red Cross, Bern-Wabern, Switzerland Abstract: Up to 80% of patients with severe posttraumatic stress disorder are suffering from “unexplained” chronic pain. Theories about the links between traumatization and chronic pain have become the subject of increased interest over the last several years. We will give a short summary about the existing interaction models that emphasize particularly psychological and behavioral aspects of this interaction. After a synopsis of the most important psychoneurobiological mechanisms of pain in the context of traumatization, we introduce the hypermnesia–hyperarousal model, which focuses on two psychoneurobiological aspects of the physiology of learning. This hypothesis provides an answer to the hitherto open question about the origin of pain persistence and pain sensitization following a traumatic event and also provides a straightforward explanatory model for educational purposes. Keywords: posttraumatic stress disorder, chronic pain, hypermnesia, hypersensitivity, traumatization

  19. Mobile platform for fish migration upstream from the discharge sill situated near Dacia bridge on Crișul Repede River

    Directory of Open Access Journals (Sweden)

    Răzvan VOICU

    2016-06-01

    Full Text Available Longitudinal connectivity represent the way in which organisms move the energy and material exchanges located throughout the water. Fragmentation the longitudinal connectivity of watercourses caused by dams or other hydrotechnical constructions represent a major impact on sediment transport, hydrological regime, downstream moving and biota migration. The hydromorphological elements (river continuity, as well as chemical, biological, physicochemical elements characterize the ecological status of rivers. Migratory fish species: nase (Chondrostoma nasus - protected by Bern Convention - Appendix III, barbel (Barbus barbus - rare species, protected Habitats Directive (Annex V, annex 4A of Low nr.462 and Red List of RBDD and Freshwater bream (Abramis brama - protected by Bern Convention (Appendix III are blocked by the hydrotechnical constructions (discharge sills, dams located across the watercourse Crișul Repede River. One of the important think of this system is the gravitational fall of water. This solution will lead to the restoration of the longitudinal connection of the Crișul Repede River in the Oradea City, near Dacia Bridge. Romania is part of the European Union and it has the obligation to implement the provisions of the Water Framework Directive 2000/60/EC, transposed into Romanian legislation by the Water Law 107/1996 as supplemented and amended (Act 310/2004.

  20. National implementation of the UNECE convention on long-range transboundary air pollution (effects). Pt. 2. Impacts and risk estimation, critical loads, biodiversity, dynamic modelling, critical level violation, material corrosion; Nationale Umsetzung UNECE-Luftreinhaltekonvention (Wirkungen). T. 2. Wirkungen und Risikoabschaetzungen Critical Loads, Biodiversitaet, Dynamische Modellierung, Critical Levels Ueberschreitungen, Materialkorrosion

    Energy Technology Data Exchange (ETDEWEB)

    Gauger, Thomas [Bundesforschungsanstalt fuer Landwirtschaft, Braunschweig (DE). Inst. fuer Agraroekologie (FAL-AOE); Stuttgart Univ. (Germany). Inst. fuer Navigation; Haenel, Hans-Dieter; Roesemann, Claus [Bundesforschungsanstalt fuer Landwirtschaft, Braunschweig (DE). Inst. fuer Agraroekologie (FAL-AOE); Nagel, Hans-Dieter; Becker, Rolf; Kraft, Philipp; Schlutow, Angela; Schuetze, Gudrun; Weigelt-Kirchner, Regine [OeKO-DATA Gesellschaft fuer Oekosystemanalyse und Umweltdatenmanagement mbH, Strausberg (Germany); Anshelm, Frank [Geotechnik Suedwest Frey Marx GbR, Bietigheim-Bissingen (Germany)

    2008-09-15

    The report on the implementation of the UNECE convention on long-range transboundary air pollution Pt.2 covers the following issues: The tasks of the NFC (National Focal Center) Germany including the ICP (international cooperative program) modeling and mapping and the expert panel for heavy metals. Results of the work for the multi-component protocol cover the initial data for the calculation of the critical loads following the mass balance method, critical loads for acid deposition, critical loads for nitrogen input, critical load violations (sulfur, nitrogen). The results of work for the heavy metal protocol cover methodology development and recommendations for ICO modeling and mapping in accordance with international development, contributions of the expert group/ task force on heavy metals (WGSR), data sets on the critical loads for lead, cadmium and mercury, and critical load violations (Pb, Cd, Hg). The results of work on the inclusion of biodiversity (BERN) cover data compilation, acquisition and integration concerning ecosystems, model validation and verification and the possible interpretation frame following the coupling with dynamic modeling. The future development and utilization of dynamic modeling covers model comparison, applicability, the preparation of a national data set and preparations concerning the interface to the BERN model.

  1. The science of exoplanets and their systems.

    Science.gov (United States)

    Lammer, Helmut; Blanc, Michel; Benz, Willy; Fridlund, Malcolm; Foresto, Vincent Coudé du; Güdel, Manuel; Rauer, Heike; Udry, Stephane; Bonnet, Roger-Maurice; Falanga, Maurizio; Charbonneau, David; Helled, Ravit; Kley, Willy; Linsky, Jeffrey; Elkins-Tanton, Linda T; Alibert, Yann; Chassefière, Eric; Encrenaz, Therese; Hatzes, Artie P; Lin, Douglas; Liseau, Rene; Lorenzen, Winfried; Raymond, Sean N

    2013-09-01

    A scientific forum on "The Future Science of Exoplanets and Their Systems," sponsored by Europlanet and the International Space Science Institute (ISSI) and co-organized by the Center for Space and Habitability (CSH) of the University of Bern, was held during December 5 and 6, 2012, in Bern, Switzerland. It gathered 24 well-known specialists in exoplanetary, Solar System, and stellar science to discuss the future of the fast-expanding field of exoplanetary research, which now has nearly 1000 objects to analyze and compare and will develop even more quickly over the coming years. The forum discussions included a review of current observational knowledge, efforts for exoplanetary atmosphere characterization and their formation, water formation, atmospheric evolution, habitability aspects, and our understanding of how exoplanets interact with their stellar and galactic environment throughout their history. Several important and timely research areas of focus for further research efforts in the field were identified by the forum participants. These scientific topics are related to the origin and formation of water and its delivery to planetary bodies and the role of the disk in relation to planet formation, including constraints from observations as well as star-planet interaction processes and their consequences for atmosphere-magnetosphere environments, evolution, and habitability. The relevance of these research areas is outlined in this report, and possible themes for future ISSI workshops are identified that may be proposed by the international research community over the coming 2-3 years.

  2. Die Ehe spaziert nicht auf der Strasse Book cover Marriage Doesn’t Grow on Trees

    Directory of Open Access Journals (Sweden)

    Sigrid Nieberle

    2005-07-01

    Full Text Available Caroline Arni rekonstruiert die Ehe und die Erfahrungen in der Ehe von ihrem Ende her, indem sie Scheidungsakten aus Bern um 1900 untersucht und auswertet. Aus diesen Analysen des „offenkundigen Unglücks“ wird hervorragend nachvollziehbar, wie eine soziokulturelle Institution in die Krise geriet, die im Laufe des 20. Jahrhunderts von Lebensformen wie Lebenspartnerschaften und patchwork families Konkurrenz bekam. Arni gelingt es, aus staubigen Aktenbergen eine kurzweilige und überaus forschungsinnovative Studie zu gewinnen.Caroline Arni reconstructs marriage and experiences in marriage from the point of its demise by examining and evaluating divorce records from Bern, Switzerland around 1900. From these analyses of “obvious catastrophe,” it becomes splendidly understandable how a sociocultural institution, which during the course of the 20th Century received competition from living arrangements such as civil unions and patchwork families, slipped into a crisis. Anri succeeds in extracting from the dusty mounds of records a study that is entertaining and exceedingly innovative in terms of research.

  3. Climatic trends and anomalies in Europe 1675-1715. High resolution spatio-temporal reconstructions from direct meteorological observations and proxy data: Methods and results

    International Nuclear Information System (INIS)

    Frenzel, B.; Pfister, C.; Glaeser, B.

    1994-01-01

    This volume contains the proceedings of a conference held at the University of Bern in Switzerland on 2-4 September 1992 by a group of historical geographers, historians, palaeobotanists and meteorologists originating from fifteen European nations as well as from China and Japan. It was the first international symposium of this kind for which the participants had previously submitted various kinds of palaeoclimatic data - early instrumental series, documentary data, dendroclimatic data - in a standardized form to a common data base in order to have this evidence ready to include in a pan-European multi-proxy mapping scheme at the time of the meeting. A team of meteorological experts worked on interpreting some of these data in terms of rough monthly synoptic weather situations in order to test the suitability of the evidence for this purpose. This volume includes both the regional contributions of the individual partners presented at the Bern workshop, as well as the two hundred monthly synoptic weather maps which resulted from the common effort of the group of meteorologists at the Copenhagen meeting. (orig.)

  4. Exploration of Icy Moons in the Outer Solar System: Updated Planetary Protection Requirements for Missions to Enceladus and Europa

    Science.gov (United States)

    Rummel, J. D.; Race, M. S.

    2016-12-01

    Enceladus and Europa are bodies with icy/watery environments and potential habitable conditions for life, making both of great interest in astrobiological studies of chemical evolution and /or origin of life. They are also of significant planetary protection concern for spacecraft missions because of the potential for harmful contamination during exploration. At a 2015 COSPAR colloquium in Bern Switzerland, international scientists identified an urgent need to establish planetary protection requirements for missions proposing to return samples to Earth from Saturn's moon Enceladus. Deliberations at the meeting resulted in recommended policy updates for both forward and back contamination requirements for missions to Europa and Enceladus, including missions sampling plumes originating from those bodies. These recently recommended COSPAR policy revisions and biological contamination requirements will be applied to future missions to Europa and Encealadus, particularly noticeable in those with plans for in situ life detection and sample return capabilities. Included in the COSPAR policy are requirementsto `break the chain of contact' with Europa or Enceladus, to keep pristine returned materials contained, and to complete required biohazard analyses, testing and/or sterilization upon return to Earth. Subsequent to the Bern meeting, additional discussions of Planetary Protection of Outer Solar System bodies (PPOSS) are underway in a 3-year study coordinated by the European Science Foundation and involving multiple international partners, including Japan, China and Russia, along with a US observer. This presentation will provide science and policy updates for those whose research or activities will involve icy moon missions and exploration.

  5. Decoding the Pantheon Columns

    Directory of Open Access Journals (Sweden)

    Gerd Grasshoff

    2014-06-01

    Full Text Available The goal of this study has been to reconstruct the design principles underlying the construction of the Pantheon’s portico columns as well as to demonstrate how digital investigation methods and models can be used to improve our understanding of ancient architectural knowledge. Thanks to the data of the Bern Digital Pantheon Model, a synthesis of all the scanned surface points obtained during a digitization campaign of the Karman Center for Advanced Studies in the Humanities of the University of Bern in 2005, we have been able to determine empirically the column profiles of the portico with unprecedented precision. A second stage of our investigation involved explaining the profile of the column shafts by a construction model that takes into account the parameters recommended by Vitruvius and design methods such as those that can be found in the construction drawings discovered at Didyma. Our analysis shows that the design principles of the portico’s columns can be successfully reconstructed, and has led to the surprising result that at least two different variants of a simple circle construction were used. Finally, we have been able to deduce from the distribution of the different profile types among the columns that the final profiles were designed and executed in Rome.

  6. Pelvic lymph node dissection in the context of radical cystectomy: a thorough insight into the connection between patient, surgeon, pathologist and treating institution

    Directory of Open Access Journals (Sweden)

    Seiler R

    2013-08-01

    Full Text Available Roland Seiler, George N Thalmann, Pascal ZehnderDepartment of Urology, University of Bern, Bern, SwitzerlandAbstract: Pelvic lymph node dissection (PLND in patients with bladder cancer varies widely in extent, technique employed, and pathological workup of specimens. The present paper provides an overview of the existing evidence regarding the effectiveness of PLND and elucidates the interactions between patient, surgeon, pathologist, and treating institution as well as their cumulative impact on the final postoperative lymph node (LN staging. Bladder cancer patients undergoing radical cystectomy with extended PLND appear to have better oncologic outcomes compared to patients undergoing radical cystectomy and limited PLND. Attempts have been made to define and assess the quality of PLND according to the number of lymph nodes identified. However, lymph node counts depend on multiple factors such as patient characteristics, surgical template, pathological workup, and institutional policies; hence, meticulous PLND within a defined and uniformly applied extended template appears to be a better assurance of quality than absolute lymph node counts. Nevertheless, the prognosis of the patients can be partially predicted with findings from the histopathological evaluation of the PLND specimen, such as the number of positive lymph nodes, extracapsular extension, and size of the largest LN metastases. Therefore, particular prognostic parameters should be addressed within the pathological report to guide the urologist in terms of patient counseling.Keywords: bladder cancer, outcome, pathological workup, postoperative staging

  7. Small hydropower plants in Switzerland: definition of spatial priorities, taking into account the conflicting interests of power production and protection of the environment

    International Nuclear Information System (INIS)

    Wehse, Heiko; Pazhepurackel, Vinitha

    2012-01-01

    Due to the promotion of small hydropower plants in Switzerland, a lot of new projects have been planned. This leads to conflicts of interests, especially between ecology and power production. Where should new power plants be built, and which rivers should be protected from any further impact ? In this paper a methodology is developed in order to find answers to those questions. It confronts the oppositional interests for the use and protection of rivers in a transparent way. By doing so, it is hoped to rationalize conflicts. The methodology should help the authorities to evaluate new projects, and it is a basis for regional strategies of river use and protection. The method was tested in collaboration with the cantonal authority of Bern to classify all the rivers of the canton (12'000 km) [Conseil-executif du canton de Berne 2009]. For each river section, the different interests were identified. It has been adapted for the canton of Fribourg to classify the river reaches where new plants are planned [Wehse 2010]. In 2011 the swiss confederation has published a recommendation for the cantonal and communal authorities, concerning the elaboration of cantonal strategies for the use and protection of the rivers [Wehse 2011], which is based on the same method. (authors)

  8. Myiasis in the imagination of a rural population in Formosa (Goiás, Brazil

    Directory of Open Access Journals (Sweden)

    Edison Rogerio Cansi

    2012-11-01

    Full Text Available Myiases are common parasitic diseases found in livestock. In Brazil, these parasitosis are popularly known as bicheira and berne according to their clinical symptoms and etiological agents. The goal of this study was to record what is known by a rural population, in Formosa (Goiás State, about myiasis in humans and domestic animals, especially cattle. Between 2009 and 2010, semi-structured interviews were conducted with 50 farmers, who answered questions about the diseases and their etiological agents, the life cycle of the parasitic species and the treatment methods used according to local traditions. The interviewees recognized the bicheiras, providing a rich repertoire of names for their etiological agents, and they knew many of the steps of their biological cycle. However, this kind of comprehensive knowledge was not known for berne; in some cases even the parasite was unknown. This research also highlights the influence of religious syncretism and popular knowledge in the treatment and management of myiasis in animals and humans.

  9. Erradicação ou manejo integrado das miíases neotropicais das Américas?

    Directory of Open Access Journals (Sweden)

    Moya Borja Gonzalo E.

    2003-01-01

    Full Text Available A erradicação da bicheira, Cochliomyia hominivorax dos EUA, da América Central e do Norte da África tornou-se uma realidade criando e liberando machos estéreis. Por que nos não decidimos também erradicar este inseto da América do Sul? Antes de tomar uma atitude corajosa, nós discutiremos neste trabalho as razões científicas, ecológicas e econômicas. O berne, Dermatobia hominis não tem sido erradicado de nenhum pais, devido a que não dispomos de técnicas para sua criação massal em dietas artificiais. Estão faltando também estudos sobre a dispersão, comportamento sexual e sítios de agregação dos adultos no campo. Devido a que as miíases continuarão sendo controladas basicamente com inseticidas, recomendações para manejar a resistência aos inseticidas e estudos sobre métodos alternativos são discutidos visando um Manejo Integrado do berne e da bicheira com fundamentos ecológicos.

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Tilman Seebass et al.

    1979-10-01

    Full Text Available - David T. Hill, Ajip Rosidi, Laut biru langit biru. Pustaka Jaya (PJ 330, Jakarta, 1977. - J.E. van Lohuizen-De Leeuw, Mildred Archer, Indian popular painting in the India Office Library, Her Majesty’s Stationery Office, London 1977, 196 pp., 92 black-and-white and 6 coloured illus. - J.M. Pluvier, R.C. Kwantes, De ontwikkeling van de nationalistische beweging in Nederlandsch-Indië; bronnenpublikatie. Tweede stuk, medio 1923-1928. Groningen, Wolters-Noordhoff, 1978. xxxviii + 783 blz. Afkortingen, woordenlijst, registers. - J.J. Ras, Niels Mulder, Mysticism and everyday life in contemporary Java, Cultural persistence and change, issued under the auspices of the Institute of Southeast Asian Studies, Singapore University Press, 1978, XIX and 150 pages. - Danker H. Schaareman, Tilman Seebass et al., The Music of Lombok. A first survey, Forum Ethnomusicologicum, Series I: Basler Studien zur Ethnomusikologie 2, Francke-Verlag Bern, 1976. 71 blz., 8 platen, 1 kaart. - Danker H. Schaareman, Ernst Schlager, Rituelle Siebenton-Musik auf Bali, Herausgegeben von Hans Oesch. Forum Ethnomusicologicum, Series I: Basler Studien zur Ethnomusikologie I, Francke-Verlag Bern, 1976. Vol I: 222 pp., Vol II: 82 musical examples. - A. Teeuw, Rainer Carle, Rendras Gedichtsammlungen (1957-1972. Ein beitrag zur kenntnis der zeitgenössischen indonesischen Literatur. Veröffentlichungen des seminars für Indonesische und Südseesprachen der Universität Hamburg. Band 11 Hamburg 1977. Verlag von Dietrich Reimer in Berlin. IV und 385 Seiten.

  11. Influenza Pandemics and Tuberculosis Mortality in 1889 and 1918: Analysis of Historical Data from Switzerland.

    Science.gov (United States)

    Zürcher, Kathrin; Zwahlen, Marcel; Ballif, Marie; Rieder, Hans L; Egger, Matthias; Fenner, Lukas

    2016-01-01

    Tuberculosis (TB) mortality declined in the northern hemisphere over the last 200 years, but peaked during the Russian (1889) and the Spanish (1918) influenza pandemics. We studied the impact of these two pandemics on TB mortality. We retrieved historic data from mortality registers for the city of Bern and countrywide for Switzerland. We used Poisson regression models to quantify the excess pulmonary TB (PTB) mortality attributable to influenza. Yearly PTB mortality rates increased during both influenza pandemics. Monthly influenza and PTB mortality rates peaked during winter and early spring. In Bern, for an increase of 100 influenza deaths (per 100,000 population) monthly PTB mortality rates increased by a factor of 1.5 (95%Cl 1.4-1.6, ppandemic. Nationally, the factor was 2.0 (95%Cl 1.8-2.2, ppandemics. We demonstrate excess PTB mortality during historic influenza pandemics in Switzerland, which supports a role for influenza vaccination in PTB patients in high TB incidence countries.

  12. Influenza Pandemics and Tuberculosis Mortality in 1889 and 1918: Analysis of Historical Data from Switzerland.

    Directory of Open Access Journals (Sweden)

    Kathrin Zürcher

    Full Text Available Tuberculosis (TB mortality declined in the northern hemisphere over the last 200 years, but peaked during the Russian (1889 and the Spanish (1918 influenza pandemics. We studied the impact of these two pandemics on TB mortality.We retrieved historic data from mortality registers for the city of Bern and countrywide for Switzerland. We used Poisson regression models to quantify the excess pulmonary TB (PTB mortality attributable to influenza.Yearly PTB mortality rates increased during both influenza pandemics. Monthly influenza and PTB mortality rates peaked during winter and early spring. In Bern, for an increase of 100 influenza deaths (per 100,000 population monthly PTB mortality rates increased by a factor of 1.5 (95%Cl 1.4-1.6, p<0.001 during the Russian, and 3.6 (95%Cl 0.7-18.0, p = 0.13 during the Spanish pandemic. Nationally, the factor was 2.0 (95%Cl 1.8-2.2, p<0.001 and 1.5 (95%Cl 1.1-1.9, p = 0.004, respectively. We did not observe any excess cancer or extrapulmonary TB mortality (as a negative control during the influenza pandemics.We demonstrate excess PTB mortality during historic influenza pandemics in Switzerland, which supports a role for influenza vaccination in PTB patients in high TB incidence countries.

  13. Predicting stability limits for pure and doped dicationic noble gas clusters undergoing coulomb explosion: A parallel tempering based study.

    Science.gov (United States)

    Ghorai, Sankar; Chaudhury, Pinaki

    2017-12-28

    We have used a replica exchange Monte-Carlo procedure, popularly known as Parallel Tempering, to study the problem of Coulomb explosion in homogeneous Ar and Xe dicationic clusters as well as mixed Ar-Xe dicationic clusters of varying sizes with different degrees of relative composition. All the clusters studied have two units of positive charges. The simulations reveal that in all the cases there is a cutoff size below which the clusters fragment. It is seen that for the case of pure Ar, the value is around 95 while that for Xe it is 55. For the mixed clusters with increasing Xe content, the cutoff limit for suppression of Coulomb explosion gradually decreases from 95 for a pure Ar to 55 for a pure Xe cluster. The hallmark of this study is this smooth progression. All the clusters are simulated using the reliable potential energy surface developed by Gay and Berne (Gay and Berne, Phys. Rev. Lett. 1982, 49, 194). For the hetero clusters, we have also discussed two different ways of charge distribution, that is one in which both positive charges are on two Xe atoms and the other where the two charges are at a Xe atom and at an Ar atom. The fragmentation patterns observed by us are such that single ionic ejections are the favored dissociating pattern. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  14. EUROPE: Swiss role

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    On its continual round of CERN Member States, the European Committee for Future Accelerators (ECFA) met in Bern, Switzerland, in March. With CERN based in Geneva, and with a national research centre at the Paul Scherrer Institute (PSI), Villigen, Switzerland figures prominently in European particle physics. The Bern ECFA meeting provided a full picture of Swiss particle physics activities, project by project, and was prefaced by an overview by Claude Joseph of Lausanne. The number of experimental particle physicists in the country is about 200, with an academic staff of about 170. These are distributed among seven universities - Basel, Bern, Fribourg, Geneva, Lausanne, Neuchâtel and Zurich. In addition there are substantial research groups at ETH-Zurich and at PSI. Probably reflecting the proximity of CERN, the size of the national research community, when scaled to the population, is above the CERN Member State average. At CERN, there is a strong Swiss participation in research at the LEP electron-positron collider (concentrated on L3), with 44 physicists. There are also 33 physicists working at the LEAR low energy antiproton ring, in particular the Crystal Barrel and CP-LEAR studies. In addition there is interest in heavy ion research and in neutrino physics (NOMAD) as well as substantial participation in research and development work for experiments at the LHC. Away from CERN, there are 6 Swiss physicists working at the HERA electron-proton collider at DESY, Hamburg, with the national PSI programme involving about 40 physicists. (The PSI programme was covered at the Bern ECFA meeting by H.C. Walter.) Following the illustrious tradition of Fritz Zwicky, Switzerland also counts many astrophysicists. Theoretical physics, with a community of some 80 researchers, has a great tradition. Throughout the 20th century, leading Swiss research centres have been beacons of brilliance. Zurich, in particular, played a leading role, with Einstein, Schrödinger and Pauli among

  15. Effects of annealing on grain-boundary character distribution and texture evolution in hot-rolled Fe-6.5 wt% Si steel

    Science.gov (United States)

    Zhang, Yang; Gokhman, Aleksandr; Wang, Wenhai; Zhang, Zhongwu

    2018-04-01

    In this paper, the effects of annealing on grain-boundary character distribution and texture evolution were investigated in hot-rolled Fe-6.5 wt% Si steel. An annealing treatment performed at different temperatures affected the recrystallization behavior and changed the volume fraction of low-angle and coincidence site lattice (CSL) boundaries. High frequencies of coincidence boundaries Σ3, Σ9, Σ13, and Σ27 were observed in all annealed samples, while the annealing temperature can lead to a large difference in frequencies for Σ13. The effect of crystallographic texture on the directional dependence of the specific magnetic energy in the rolling plane of investigated sheets was calculated and discussed. These results demonstrate the possibility of optimizing grain-boundary character distribution (GBCD) and texture to improve the magnetic and mechanical properties of Fe-6.5 wt% Si steel by controlling annealing temperature.

  16. [Evaluation of music department students who passed the entrance exam with phonetogram (Voice Range Profile)].

    Science.gov (United States)

    Gökdoğan, Çağıl; Gökdoğan, Ozan; Şahin, Esra; Yılmaz, Metin

    2014-01-01

    This study aims to evaluate phonetogram data of the students in the department of music who passed the entrance exam. The phonetogram data of 44 individuals with a good voice quality in the department of music and age-matched individuals who were not trained in the field of music or not involved in music amateurish as the control group were compared. The voice of both groups were recorded using the voice range profile within the scope of Kay Elemetrics CSL (Model 4300 B) programmed. There was a significant difference in the voice range profile parameters including max Fo, Fo range, Fo range (St), min dB SPL, and max dB sound pressure level (pmusic is higher than the control group and that plays a major role in their acceptance to the department of music.

  17. 3D Microstructural Characterization of Uranium Oxide as a Surrogate Nuclear Fuel: Effect of Oxygen Stoichiometry on Grain Boundary Distributions

    Energy Technology Data Exchange (ETDEWEB)

    Rudman, K. [Arizona State Univ., Tempe, AZ (United States); Dickerson, P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Byler, Darrin David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Peralta, P. [Arizona State Univ., Tempe, AZ (United States); Lim, H. [Arizona State Univ., Tempe, AZ (United States); McDonald, R. [Arizona State Univ., Tempe, AZ (United States); Dickerson, R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mcclellan, Kenneth James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-06

    The initial microstructure of an oxide fuel can play a key role in its performance. At low burn-ups, the diffusion of fission products can depend strongly on grain size and grain boundary (GB) characteristics, which in turn depend on processing conditions and oxygen stoichiometry. Serial sectioning techniques using Focused Ion Beam were developed to obtain Electron Backscatter Diffraction (EBSD) data for depleted UO2 pellets that were processed to obtain 3 different oxygen stoichiometries. The EBSD data were used to create 3D microstructure reconstructions and to gather statistical information on the grain and GB crystallography, with emphasis on identifying the character (twist, tilt, mixed) for GBs that meet the Coincident Site Lattice (CSL) criterion as well as GBs with the most common misorientation angles. Data on dihedral angles at triple points were also collected. The results were compared across different samples to understand effects of oxygen content on microstructure evolution.

  18. The DARWIN breadboard cryogenic optical delay line

    Science.gov (United States)

    van den Dool, T. C.; Gielesen, W.; Kamphues, F.; Loix, N.; Kooijman, P. P.; de Vries, C.; van Weers, H.; Fleury, K.; Stockman, Y.; Velsink, G.; Benoit, J.; Poupinet, A.; Sève, F.

    2017-11-01

    TNO, in cooperation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line (figure 1) for use in future space interferometry missions. The work is performed under ESA contract 17.747/03 in preparation for the DARWIN mission. The breadboard (BB) delay line is representative of a flight mechanism. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD) control, driving a twomirror cat's eye. Magnetic bearings provide frictionless and wear free operation with zero-hysteresis. The design of the BB delay line has been completed. The development test program, including operation at 100 K has been completed. The verification test programme is currently being carried out and will include functional testing at 40 K.

  19. Interferometry of light particles with a CsI(Tl) multi-detector in the collision: 16O(93.6 MeV/A) + 197Au

    International Nuclear Information System (INIS)

    Goujdami, D.

    1987-01-01

    Back angle emissions of light particles have been studied by interferometry in the 16 0 + 197 Au reaction. The experiment was performed at GANIL at 93,6 MeV/A. To achieve the correlation functions in the average backward direction we built entirely a compact multi-detector of Csl scintillators which was set up at 115 degrees to the beam direction. This work describes the relevant tests of the detector, data taking and data processing. The p-p, α-α, d-d, α-d, α-t correlations that we studied exhibit a complete damping of two body resonant nuclear effects. The most surprising result concerns the p-p correlation which, by its new shape, could be the signature of a de-excitation process in two steps. The ordering time of the 2 proton cascade would be of the order of 1.5*10 -21 s. (author) [fr

  20. Installation restoration program site investigation. Gulfport Field Training Site, Mississippi Air National Guard Gulfport-Biloxi Regional Airport Gulfport, Mississippi. Volume 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-12-01

    Site Investigation Report, Volume: 2. A Site Investigation was performed at 3 sites at the Combat Readiness Training Center, Gulfport-Bolixi. The 3 sites investigated are the: Former Fire Training Area (Site 1), the Former JP-4 Bulk Storage Area, Mill Road (Site 2), and the Motor Pool Above-Ground Diesel Fuel Storage Tank Area (Site 3). The findings of this investigation recommended further investigation at the Fire Training Area and the JP-4 Bulk Storage Tank. At Site 3 the levels of contamination did not represent a risk to human health or the environment; therefore, no further action was recommended. Volume two of this report consisted of the following Appendixes: Site Photographs (A), Well Inventory (B), Boring Logs (C), CSL Technical Memorandum (D), Data Review and Validation (E), GPS Memorandum (F), Level C Analytical Data Summary Tables (G), Slug Test (H), Special-Status Species (I), and Representative Species of Less Mobile Fish and Wildlife (J).

  1. Improvement of corrosion resistance in austenitic stainless steel by grain boundary character distribution control

    International Nuclear Information System (INIS)

    Wang, Yun; Kaneda, Junya; Kasahara, Shigeki; Shigenaka, Naoto

    2012-01-01

    Strauss test, Coriou test and Huey test were conducted on a Type 316L austenitic stainless steel. Improvement in grain boundary corrosion resistance was verified after raising low Σ coincidence site lattice (CSL) grain boundary (GB) frequency by controlling grain boundary character distribution (GBCD). During crevice corrosion test under gamma-ray irradiation, initiation frequency of GB corrosion after GBCD controlled specimens decreased to 1/10 of GBCD uncontrolled counterpart along with lower depth of corrosion. Stress corrosion cracking (SCC) propagation rate of GBCD controlled specimen decreased to less than 1/2 of GBCD uncontrolled specimen in high temperature and high pressure water. Based on these results, we expect that GBCD control will improve corrosion resistance of austenitic material in a wide range of application and environment. (author)

  2. Renewing UPEI’s Institutional Repository: New Features for an Islandora-based Environment

    Directory of Open Access Journals (Sweden)

    Donald Moses

    2013-07-01

    Full Text Available In October of 2012, the University of Prince Edward Island (UPEI launched an updated version of IslandScholar, UPEI’s Institutional repository. The repository, available from http://www.islandscholar.ca, is built on Islandora 6 (http://islandora.ca. The repository includes a number of new features, including: CSL integration for ingest, site display, and export of user-specific bibliographies; MADS-based Authority integration for Departments and Authors (with authorities created automatically using LDAP; batch ingest from Refworks (crosswalked to MODS for storage in the repository; embargo and statistics functions. Features from the first version of IslandScholar were also migrated to the new site, including Sherpa/Romeo integration (which provides just-in-time information about open access policies.

  3. Mutagenesis Strategies for the Enhancement of Glucose Oxidase Production from Corn Steep Liquor

    International Nuclear Information System (INIS)

    Khalaf, M.A.

    2007-01-01

    During screening of the twenty eight Aspergillus and Penicillium species for GOD production, only A. niger (84) was observed to release high extra (3.15 U ml -1 ) and intracellular (9.30 U mg -l ) GOD activity. Conidia of A. niger S4 were subjected to mutagenesis with UV radiation, nitrous acid, and sodium azide, as a single or combined treatments, and GOD activity was detected with the diffusion plate method. Out of 27 over producing mutants tested in shaken flasks, UVNA54 mutant strain showed the highest level of GOD activity (171 %, higher than the wild type). Using CSL at concentration 25 ml rl as the sol nutrient source, the enzyme activity was increased to 5.16 U ml -1 and 22.40 U mg -1 for extra and intracellular, respectively. Viable cell numbers of Pseudomonas and Salmonella spp. decreased as the concentration of the produced enzyme increased from 1 to 3 U ml -1

  4. Grain boundary engineering for control of tellurium diffusion in GH3535 alloy

    Science.gov (United States)

    Fu, Cai-Tao; Yinling, Wang; Chu, Xiang-Wei; Jiang, Li; Zhang, Wen-Zhu; Bai, Qin; Xia, Shuang; Leng, Bin; Li, Zhi-Jun; Ye, Xiang-Xi; Liu, Fang

    2017-12-01

    The effect of grain boundary engineering (GBE) on the Te diffusion along the surface grain boundaries was investigated in GH3535 alloy. It can be found that GBE treatment increases obviously the fraction of low-Σ coincidence site lattice (CSL) boundaries, especially the Σ3 ones, and introduces the large-size grain clusters. When the as-received (AR) and GBE-treated (GBET) specimens were exposed to Te vapor, only Σ3 boundaries were found to be resistant to Te diffusion. From the cross section and the surface, the fewer Te-attacked grain boundaries and the thinner corrosion layer can be observed in the GBET sample. The improvement of resistance to Te diffusion in the GBET sample can be attributed to the large size grain-clusters associated with high proportion of the Σ3n boundaries.

  5. Emergence of chiral spin liquids via quantum melting of noncoplanar magnetic orders

    Science.gov (United States)

    Hickey, Ciarán; Cincio, Lukasz; Papić, Zlatko; Paramekanti, Arun

    2017-09-01

    Quantum spin liquids (QSLs) are highly entangled states of quantum magnets which lie beyond the Landau paradigm of classifying phases of matter via broken symmetries. A physical route to arriving at QSLs is via frustration-induced quantum melting of ordered states such as valence bond crystals or magnetic orders. Here we show, using extensive exact diagonalization (ED) and density-matrix renormalization group (DMRG) studies of concrete S U (2 ) invariant spin models on honeycomb, triangular, and square lattices, that chiral spin liquids (CSLs) emerge as descendants of triple-Q spin crystals with tetrahedral magnetic order and a large scalar spin chirality. Such ordered-to-CSL melting transitions may yield lattice realizations of effective Chern-Simons-Higgs field theories. Our work provides a distinct unifying perspective on the emergence of CSLs and suggests that materials with certain noncoplanar magnetic orders might provide a good starting point to search for CSLs.

  6. Grain Boundary Evolution of Cold-Rolled FePd Alloy during Recrystallization at Disordering Temperature

    Science.gov (United States)

    Lin, Hung-Pin; Chen, Delphic; Kuo, Jui-Chao

    2015-01-01

    In this study, the grain boundary character and texture of 50% and 90% cold-rolled FePd alloy was investigated during recrystallization at 700 °C. Electron backscatter diffraction (EBSD) measurements were performed on the rolling direction to normal direction section. Kernel average misorientation (KAM) calculated from EBSD measurements was employed to determine the recrystallization fraction. The Avrami exponent n of recrystallization is 1.9 and 4.9 for 50% and 90% cold rolling, respectively. The new formation of texture reveals random texture during the recrystallization process. As annealing time increased, the number of high angle boundary (HAGB) and coincidence site lattice (CSL) increased with consumption of low angle boundary (LAGB). In addition, possible transformations between different grain boundaries are observed here.

  7. Grain Boundary Engineering the Mechanical Properties of Allvac 718Plus(Trademark) Superalloy

    Science.gov (United States)

    Gabb, Timothy P.; Telesman, Jack; Garg, Anita; Lin, Peter; Provenzano, virgil; Heard, Robert; Miller, Herbert M.

    2010-01-01

    Grain Boundary Engineering can enhance the population of structurally-ordered "low S" Coincidence Site Lattice (CSL) grain boundaries in the microstructure. In some alloys, these "special" grain boundaries have been reported to improve overall resistance to corrosion, oxidation, and creep resistance. Such improvements could be quite beneficial for superalloys, especially in conditions which encourage damage and cracking at grain boundaries. Therefore, the effects of GBE processing on high-temperature mechanical properties of the cast and wrought superalloy Allvac 718Plus (Allvac ATI) were screened. Bar sections were subjected to varied GBE processing, and then consistently heat treated, machined, and tested at 650 C. Creep, tensile stress relaxation, and dwell fatigue crack growth tests were performed. The influences of GBE processing on microstructure, mechanical properties, and associated failure modes are discussed.

  8. The CSLA and CSLC Families: Recent Advances and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Aaron Howard Liepman

    2012-05-01

    Full Text Available The CELLULOSE SYNTHASE (CESA superfamily of proteins contains several sub-families of closely related CELLULOSE SYNTHASE-LIKE (CSL sequences, Among these, the CSLA and CSLC families are closely related to each other and are the most evolutionarily divergent from the CESA family. Significant progress has been made with the functional characterization of CSLA and CSLC genes, which have been shown to encode enzymes with 1,4-B-glycan synthase activities involved in the biosynthesis of mannan and possibly xyloglucan backbones, respectively. This review examines recent work on the CSLA and CSLC families from evolutionary, molecular, and biochemical perspectives. We pose a series of questions, whose answers likely will provide further insight about the specific functions of members of the CSLA and CSLC families and about plant polysaccharide biosynthesis is general.

  9. PVeStA: A Parallel Statistical Model Checking and Quantitative Analysis Tool

    KAUST Repository

    AlTurki, Musab

    2011-01-01

    Statistical model checking is an attractive formal analysis method for probabilistic systems such as, for example, cyber-physical systems which are often probabilistic in nature. This paper is about drastically increasing the scalability of statistical model checking, and making such scalability of analysis available to tools like Maude, where probabilistic systems can be specified at a high level as probabilistic rewrite theories. It presents PVeStA, an extension and parallelization of the VeStA statistical model checking tool [10]. PVeStA supports statistical model checking of probabilistic real-time systems specified as either: (i) discrete or continuous Markov Chains; or (ii) probabilistic rewrite theories in Maude. Furthermore, the properties that it can model check can be expressed in either: (i) PCTL/CSL, or (ii) the QuaTEx quantitative temporal logic. As our experiments show, the performance gains obtained from parallelization can be very high. © 2011 Springer-Verlag.

  10. Monte Carlo Simulations of Background Spectra in Integral Imager Detectors

    Science.gov (United States)

    Armstrong, T. W.; Colborn, B. L.; Dietz, K. L.; Ramsey, B. D.; Weisskopf, M. C.

    1998-01-01

    Predictions of the expected gamma-ray backgrounds in the ISGRI (CdTe) and PiCsIT (Csl) detectors on INTEGRAL due to cosmic-ray interactions and the diffuse gamma-ray background have been made using a coupled set of Monte Carlo radiation transport codes (HETC, FLUKA, EGS4, and MORSE) and a detailed, 3-D mass model of the spacecraft and detector assemblies. The simulations include both the prompt background component from induced hadronic and electromagnetic cascades and the delayed component due to emissions from induced radioactivity. Background spectra have been obtained with and without the use of active (BGO) shielding and charged particle rejection to evaluate the effectiveness of anticoincidence counting on background rejection.

  11. Conductive sub-layer of twisted-tape-induced swirl-flow heat transfer in vertical circular tubes with various twisted-tape inserts

    Science.gov (United States)

    Hata, K.; Fukuda, K.; Masuzaki, S.

    2018-04-01

    conductive sub-layer δ CSL and the nondimensional thickness of the conductive sub-layer y + CSL on the circular tubes with various twisted-tape inserts were determined on the basis of numerical solutions for the swirl velocities u sw ranging from 5.23 to 21.18 m/s. Correlations between the conductive sub-layer thickness δ CSL and the nondimensional thickness of the conductive sub-layer y + CSL for twisted-tape-induced swirl-flow heat transfer in a vertical circular tube were derived.

  12. Ultrathin HfON/SiO2 dual tunneling layer for improving the electrical properties of metal–oxide–nitride–oxide–silicon memory

    International Nuclear Information System (INIS)

    Liu, L.; Xu, J.P.; Chen, J.X.; Ji, F.; Huang, X.D.; Lai, P.T.

    2012-01-01

    A high-k gate stack structure with ultrathin HfON/SiO 2 as dual tunneling layer (DTL), AlN as charge storage layer (CSL) and HfAlO as blocking layer (BL) is proposed to make a charge-trapping-type metal–oxide–nitride–oxide–silicon non-volatile memory device by employing in-situ sputtering method. The validity of the structure is examined and confirmed by transmission electron microscopy. The memory window, program/erase, endurance and retention properties are investigated and compared with similar gate stack structure with Si 3 N 4 /SiO 2 as DTL, HfO 2 as CSL and Al 2 O 3 as BL. Results show that a large memory window of 3.55 V at a program/erase (P/E) voltage of + 8 V/− 15 V, high P/E speed, and good endurance and retention characteristic can be achieved using the Au/ HfAlO/AlN/(HfON/SiO 2 )/Si gate stack structure. The main mechanisms lie in the enhanced electron injection through the ultrathin high-k HfON/SiO 2 DTL with suitable band offset, high trapping efficiency of the high-k AlN material, and effective blocking role of the high-k HfAlO BL. - Highlights: ► An Au/HfAlO/AlN/(HfON/SiO 2 )/Si high-k gate stack structure is proposed. ► A band-engineered dual tunneling layer (HfON/SiO 2 ) is proposed and prepared. ► A good trade-off among the memory characteristics is obtained. ► In-situ sputtering method is employed to fabricate the gate stack structure.

  13. Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines

    Directory of Open Access Journals (Sweden)

    Chen Lei

    2011-06-01

    Full Text Available Abstract Background Cancer stem cells (CSCs are regarded as the cause of tumor formation and recurrence. The isolation and identification of CSCs could help to develop novel therapeutic strategies specifically targeting CSCs. Methods Human hepatoma cell lines were plated in stem cell conditioned culture system allowed for sphere forming. To evaluate the stemness characteristics of spheres, the self-renewal, proliferation, chemoresistance, tumorigenicity of the PLC/PRF/5 sphere-forming cells, and the expression levels of stem cell related proteins in the PLC/PRF/5 sphere-forming cells were assessed, comparing with the parental cells. The stem cell RT-PCR array was performed to further explore the biological properties of liver CSCs. Results The PLC/PRF/5, MHCC97H and HepG2 cells could form clonal nonadherent 3-D spheres and be serially passaged. The PLC/PRF/5 sphere-forming cells possessed a key criteria that define CSCs: persistent self-renewal, extensive proliferation, drug resistance, overexpression of liver CSCs related proteins (Oct3/4, OV6, EpCAM, CD133 and CD44. Even 500 sphere-forming cells were able to form tumors in NOD/SCID mice, and the tumor initiating capability was not decreased when spheres were passaged. Besides, downstream proteins DTX1 and Ep300 of the CSL (CBF1 in humans, Suppressor of hairless in Drosophila and LAG1 in C. elegans -independent Notch signaling pathway were highly expressed in the spheres, and a gamma-secretase inhibitor MRK003 could significantly inhibit the sphere formation ability. Conclusions Nonadherent tumor spheres from hepatoma cell lines cultured in stem cell conditioned medium possess liver CSC properties, and the CSL-independent Notch signaling pathway may play a role in liver CSCs.

  14. Optimization of low-cost biosurfactant production from agricultural residues through response surface methodology.

    Science.gov (United States)

    Ebadipour, N; Lotfabad, T Bagheri; Yaghmaei, S; RoostaAzad, R

    2016-01-01

    Biosurfactants are surface-active compounds capable of reducing surface tension and interfacial tension. Biosurfactants are produced by various microorganisms. They are promising replacements for chemical surfactants because of biodegradability, nontoxicity, and their ability to be produced from renewable sources. However, a major obstacle in producing biosurfactants at the industrial level is the lack of cost-effectiveness. In the present study, by using corn steep liquor (CSL) as a low-cost agricultural waste, not only is the production cost reduced but a higher production yield is also achieved. Moreover, a response surface methodology (RSM) approach through the Box-Behnken method was applied to optimize the biosurfactant production level. The results found that biosurfactant production was improved around 2.3 times at optimum condition when the CSL was at a concentration of 1.88 mL/L and yeast extract was reduced to 25 times less than what was used in a basic soybean oil medium (SOM). The predicted and experimental values of responses were in reasonable agreement with each other (Pred-R(2) = 0.86 and adj-R(2) = 0.94). Optimization led to a drop in raw material price per unit of biosurfactant from $47 to $12/kg. Moreover, the biosurfactant product at a concentration of 84 mg/L could lower the surface tension of twice-distilled water from 72 mN/m to less than 28 mN/m and emulsify an equal volume of kerosene by an emulsification index of (E24) 68% in a two-phase mixture. These capabilities made these biosurfactants applicable in microbial enhanced oil recovery (MEOR), hydrocarbon remediation, and all other petroleum industry surfactant applications.

  15. Use of Potato Nitrogen Concentrate in the Production of α-Amylase by Aspergillus oryzae

    Directory of Open Access Journals (Sweden)

    Eric Thaller

    2007-01-01

    Full Text Available The influence of various nitrogen sources and media supplements on α-amylase (EC 3.2.1.1 formation by Aspergillus oryzae ATCC 1011 was investigated in shake flask experiments and batch fermentations. Both inorganic and organic nitrogen-containing supplements have been applied, while corn starch and ammonium sulphate were used as the major source of carbon and nitrogen, respectively. Shake flask experiments revealed that potato nitrogen concentrate (PNC is almost equivalent to corn steep liquor (CSL in supporting amylase formation. A pretreatment step consisting of clarification of the turbid material did not show any significant effect. The replacement of the inorganic nitrogen source by sodium nitrate led to lower enzyme yields. Other complex supplements may reduce the enzyme level formed, e.g. casein hydrolysate, or increase the amylase titre slightly, e.g. yeast extract or malt extract. Cultivations in instrumented bench top reactors on media supplemented with PNC led to higher cell growth rates and yields of α-amylase in comparison with the medium without any supplement. Replacement of PNC by CSL revealed a slightly increased enzyme level, which is in the range of 9–17 % after 100 h of cultivation. Only minor differences were revealed in the growth kinetics and enzyme formation when PNC was used as the sole nitrogen source, replacing a mixture of soybean meal, yeast extract, malt extract and casein hydrolysate in bioreactor cultivations with lactose as the carbon source. However, metabolic differences as seen from the course of dissolved oxygen tension (DOT, α-amino nitrogen concentration and the amount of acid needed to maintain a constant pH were observed.

  16. Integrative analysis and expression profiling of secondary cell wall genes in C4 biofuel model Setaria italica reveals targets for lignocellulose bioengineering

    Directory of Open Access Journals (Sweden)

    Mehanathan eMuthamilarasan

    2015-11-01

    Full Text Available Several underutilized grasses have excellent potential for use as bioenergy feedstock due to their lignocellulosic biomass. Genomic tools have enabled identification of lignocellulose biosynthesis genes in several sequenced plants. However, the non-availability of whole genome sequence of bioenergy grasses hinders the study on bioenergy genomics and their genomics-assisted crop improvement. Foxtail millet (Setaria italica L.; Si is a model crop for studying systems biology of bioenergy grasses. In the present study, a systematic approach has been used for identification of gene families involved in cellulose (CesA/Csl, callose (Gsl and monolignol biosynthesis (PAL, C4H, 4CL, HCT, C3H, CCoAOMT, F5H, COMT, CCR, CAD and construction of physical map of foxtail millet. Sequence alignment and phylogenetic analysis of identified proteins showed that monolignol biosynthesis proteins were highly diverse, whereas CesA/Csl and Gsl proteins were homologous to rice and Arabidopsis. Comparative mapping of foxtail millet lignocellulose biosynthesis genes with other C4 panicoid genomes revealed maximum homology with switchgrass, followed by sorghum and maize. Expression profiling of candidate lignocellulose genes in response to different abiotic stresses and hormone treatments showed their differential expression pattern, with significant higher expression of SiGsl12, SiPAL2, SiHCT1, SiF5H2 and SiCAD6 genes. Further, due to the evolutionary conservation of grass genomes, the insights gained from the present study could be extrapolated for identifying genes involved in lignocellulose biosynthesis in other biofuel species for further characterization.

  17. Relativistic model for statevector reduction

    International Nuclear Information System (INIS)

    Pearle, P.

    1991-04-01

    A relativistic quantum field model describing statevector reduction for fermion states is presented. The time evolution of the states is governed by a Schroedinger equation with a Hamiltonian that has a Hermitian and a non-Hermitian part. In addition to the fermions, the Hermitian part describes positive and negative energy mesons of equal mass, analogous to the longitudinal and timelike photons of electromagnetism. The meson-field-sum is coupled to the fermion field. This ''dresses'' each fermion so that, in the extreme nonrelativistic limit (non-moving fermions), a fermion in a position eigenstate is also in an eigenstate of the meson-field-difference with the Yukawa-potential as eigenvalue. However, the fermions do not interact: this is a theory of free dressed fermions. It is possible to obtain a stationary normalized ''vacuum'' state which satisfies two conditions analogous to the gauge conditions of electromagnetism (i.e., that the meson-field-difference, as well as its time derivative, give zero when applied to the vacuum state), to any desired degree of accuracy. The non-Hermitian part of the Hamiltonian contains the coupling of the meson-field-difference to an externally imposed c-number fluctuating white noise field, of the CSL (Continuous Spontaneous Localization) form. This causes statevector reduction, as is shown in the extreme nonrelativistic limit. For example, a superposition of spatially separated wavepackets of a fermion will eventually be reduced to a single wavepacket: the meson-field-difference discriminates among the Yukawa-potential ''handles'' attached to each wavepacket, thereby selecting one wavepacket to survive by the CSL mechanism. Analysis beyond that given in this paper is required to see what happens when the fermions are allowed to move. (It is possible that the ''vacuum'' state becomes involved in the dynamics so that the ''gauge'' conditions can no longer be maintained.) It is shown how to incorporate these ideas into quantum

  18. Prospecting for Energy-Rich Renewable Raw Materials: Sorghum Stem Case Study.

    Directory of Open Access Journals (Sweden)

    Caitlin S Byrt

    Full Text Available Sorghum vegetative tissues are becoming increasingly important for biofuel production. The composition of sorghum stem tissues is influenced by genotype, environment and photoperiod sensitivity, and varies widely between varieties and also between different stem tissues (outer rind vs inner pith. Here, the amount of cellulose, (1,3;1,4-β-glucan, arabinose and xylose in the stems of twelve diverse sorghum varieties, including four photoperiod-sensitive varieties, was measured. At maturity, most photoperiod-insensitive lines had 1% w/w (1,3;1,4-β-glucan in stem pith tissue whilst photoperiod-sensitive varieties remained in a vegetative stage and accumulated up to 6% w/w (1,3;1,4-β-glucan in the same tissue. Three sorghum lines were chosen for further study: a cultivated grain variety (Sorghum bicolor BTx623, a sweet variety (S. bicolor Rio and a photoperiod-sensitive wild line (S. bicolor ssp. verticilliflorum Arun. The Arun line accumulated 5.5% w/w (1,3;1,4-β-glucan and had higher SbCslF6 and SbCslH3 transcript levels in pith tissues than did photoperiod-insensitive varieties Rio and BTx623 (<1% w/w pith (1,3;1,4-β-glucan. To assess the digestibility of the three varieties, stem tissue was treated with either hydrolytic enzymes or dilute acid and the release of fermentable glucose was determined. Despite having the highest lignin content, Arun yielded significantly more glucose than the other varieties, and theoretical calculation of ethanol yields was 10 344 L ha-1 from this sorghum stem tissue. These data indicate that sorghum stem (1,3;1,4-β-glucan content may have a significant effect on digestibility and bioethanol yields. This information opens new avenues of research to generate sorghum lines optimised for biofuel production.

  19. Automated Light- and Dark-Adapted Perimetry for Evaluating Retinitis Pigmentosa: Filling a Need to Accommodate Multicenter Clinical Trials.

    Science.gov (United States)

    McGuigan, David B; Roman, Alejandro J; Cideciyan, Artur V; Matsui, Rodrigo; Gruzensky, Michaela L; Sheplock, Rebecca; Jacobson, Samuel G

    2016-06-01

    The purpose of this study was to develop a convenient means to measure rod (and cone) function by automated perimetry in patients with inherited retinal degenerations (IRDs). A currently available automated perimeter was used to determine sensitivity (in decibels) to a blue target in the dark-adapted (DA) state and a white target in the light-adapted (LA) state. Normal subjects and IRD patients were evaluated with a full-threshold 71-locus strategy (the retinitis pigmentosa [RP] test) and a size III target. Comparisons were made with results from the more commonly used methods of two-color DA perimetry and middle/long-wavelength LA perimetry in the same patients. Rod function using the blue target and the RP test was determined for normal subjects by measuring DA sensitivities. If patients detected the blue stimulus in the DA state, it was determined whether the value was rod mediated by using normal data acquired during the cone plateau phase of dark adaptation. If rod mediated, rod sensitivity loss (RSL) was calculated and mapped across the visual field. Light-adapted sensitivities in normal subjects were also measured, permitting cone sensitivity losses (CSL) to be calculated for the patients. Multiple methods were used to compare RSL and CSL results with those from two-color DA perimetry and chromatic LA perimetry, and there was close correspondence between the methods. The unmodified automated static perimeter used in the DA and LA states presents a practical approach to accomplish current goals of treatment trials in IRDs. This proof-of-principle study is an initial step toward establishing a clinical method to gather reproducible data on photoreceptor-mediated sensitivity.

  20. Impact of the 2015 El Niño-Southern Oscillation on the Abundance and Foraging Habits of Guadalupe Fur Seals and California Sea Lions from the San Benito Archipelago, Mexico

    Science.gov (United States)

    Elorriaga-Verplancken, Fernando R.; Sierra-Rodríguez, Gema E.; Rosales-Nanduca, Hiram; Acevedo-Whitehouse, Karina; Sandoval-Sierra, Julieta

    2016-01-01

    The abundance of California sea lions (Zalophus californianus) (CSLs) and Guadalupe fur seals (Arctocephalus philippii townsendi) (GFSs) from the San Benito Archipelago (SBA) was determined through nine monthly surveys in 2014–2015. Assessment of their foraging habits was examined based on the isotopic analysis of pups (maternal indicators) (SIAR/SIBER-R). Environmental variability between 2014 and 2015 was also analyzed, in terms of sea surface temperature (SST) and chlorophyll (Chl-a) concentration. Both otariids reached their highest abundance in July of both years; however, relative to 2014, the 2015 survey showed a 59.7% decline in the total GFS abundance and a 42.9% decrease of GFS pups, while total CSL abundance decreased 52.0% and CSL pup presence decreased in 61.7%. All monthly surveys for both otariids showed a similar trend (>50% decrease in 2015). Compared to 2014, the 2015 GFSs isotopic niche was three times larger (2.0 in 2015, 0.6 in 2014) and the δ13C was significantly lower. CSLs also showed significantly lower δ13C and higher δ15N in 2015. Interannual segregation was greater for CSLs, and their pup body mass was also significantly lower during the 2015 breeding season (mean = 8.7 kg) than in the same season of 2014 (mean = 9.9 kg). The decrease in δ13C for both otariids reflected a more oceanic foraging; most likely associated with the decline in primary productivity in surrounding areas to the SBA, related to a higher SST caused by the 2015 ENSO, with a subsequent increase in foraging effort. These would explain the fewer observed individuals on land, especially pups, which showed diminished body condition (CSLs). This study highlights the importance of marine mammals as sentinel species that respond dynamically to changes in environment, providing valuable information on the effect of ENSO on pinnipeds in Mexican waters. PMID:27171473

  1. Rapid Separation of Three Proanthocyanidin Dimers from Iris lactea Pall. var. Chinensis (Fisch.) Koidz by High-Speed Counter-Current Chromatography With Continuous Sample Load and Double-Pump Balancing Mode.

    Science.gov (United States)

    Lv, Huanhuan; Yuan, Zhenzhen; Wang, Xiaoyan; Wang, Zhenhua; Suo, Yourui; Wang, Honglun

    2015-01-01

    The dried seeds of Iris lactea have been used in traditional Chinese medicine. Previous studies have been focused on irisquinones while other chemical components are rarely reported. To establish an efficient high-speed counter-current chromatography (HSCCC) separation method with continuous sample load (CSL) and double-pump balancing (DPB) mode to isolate proanthocyanidins from I. lactea. Firstly, an ethyl acetate extract of I. lactea was pre-fractionated by silica column chromatography for the enrichment of proanthocyanidins. Secondly, the enriched proanthocyanidins sample (EPS) was further fractionated by HSCCC with a two-phase solvent system ethyl acetate:n-butanol:water (9:1:10, v/v/v) using DPB mode. The flow rate of the two phases was 2.2 mL/min, the revolution speed was 900 rpm, the separation temperature was 30 °C and the detection wavelength was 280 nm. Finally, the structures of the three isolated proanthocyanidins were elucidated by spectroscopic methods and compared with published data. Under the optimized conditions, 600 mg of the EPS with six continuous injections (100 mg/time) was fractionated, yielding 57 mg of prodelphinidin B3, 198 mg of procyanidin B3, and 162 mg of procyanidin B1, at purities of 97.2%, 98.1% and 97.3%, respectively. The HSCCC separation method with CSL and DPB proved to be rapid, convenient and economical, constituting an efficient strategy for the isolation of proanthocyanidins. Copyright © 2015 John Wiley & Sons, Ltd.

  2. Multi-scale modeling and analysis of convective boiling: towards the prediction of CHF in rod bundles

    International Nuclear Information System (INIS)

    Niceno, B.; Sato, Y.; Badillo, A.; Andreani, M.

    2010-01-01

    In this paper we describe current activities on the project Multi-Scale Modeling and Analysis of convective boiling (MSMA), conducted jointly by the Paul Scherrer Institute (PSI) and the Swiss Nuclear Utilities (Swissnuclear). The long-term aim of the MSMA project is to formulate improved closure laws for Computational Fluid Dynamics (CFD) simulations for prediction of convective boiling and eventually of the Critical Heat Flux (CHF). As boiling is controlled by the competition of numerous phenomena at various length and time scales, a multi-scale approach is employed to tackle the problem at different scales. In the MSMA project, the scales on which we focus range from the CFD scale (macro-scale), bubble size scale (meso-scale), liquid micro-layer and triple interline scale (micro-scale), and molecular scale (nano-scale). The current focus of the project is on micro- and meso- scales modeling. The numerical framework comprises a highly efficient, parallel DNS solver, the PSI-BOIL code. The code has incorporated an Immersed Boundary Method (IBM) to tackle complex geometries. For simulation of meso-scales (bubbles), we use the Constrained Interpolation Profile method: Conservative Semi-Lagrangian 2nd order (CIP-CSL2). The phase change is described either by applying conventional jump conditions at the interface, or by using the Phase Field (PF) approach. In this work, we present selected results for flows in complex geometry using the IBM, selected bubbly flow simulations using the CIP-CSL2 method and results for phase change using the PF approach. In the subsequent stage of the project, the importance of effects of nano-scale processes on the global boiling heat transfer will be evaluated. To validate the models, more experimental information will be needed in the future, so it is expected that the MSMA project will become the seed for a long-term, combined theoretical and experimental program

  3. Characterization of microstructure and texture across dissimilar super duplex/austenitic stainless steel weldment joint by austenitic filler metal

    International Nuclear Information System (INIS)

    Eghlimi, Abbas; Shamanian, Morteza; Eskandarian, Masoomeh; Zabolian, Azam; Szpunar, Jerzy A.

    2015-01-01

    The evolution of microstructure and texture across an as-welded dissimilar UNS S32750 super duplex/UNS S30403 austenitic stainless steel joint welded by UNS S30986 (AWS A5.9 ER309LMo) austenitic stainless steel filler metal using gas tungsten arc welding process was evaluated by optical micrography and EBSD techniques. Due to their fabrication through rolling process, both parent metals had texture components resulted from deformation and recrystallization. The weld metal showed the highest amount of residual strain and had large austenite grain colonies of similar orientations with little amounts of skeletal ferrite, both oriented preferentially in the < 001 > direction with cub-on-cube orientation relationship. While the super duplex stainless steel's heat affected zone contained higher ferrite than its parent metal, an excessive grain growth was observed at the austenitic stainless steel's counterpart. At both heat affected zones, austenite underwent some recrystallization and formed twin boundaries which led to an increase in the fraction of high angle boundaries as compared with the respective base metals. These regions showed the least amount of residual strain and highest amount of recrystallized austenite grains. Due to the static recrystallization, the fraction of low degree of fit (Σ) coincident site lattice boundaries, especially Σ3 boundaries, was increased in the austenitic stainless steel heat affected zone, while the formation of subgrains in the ferrite phase increased the content of < 5° low angle boundaries at that of the super duplex stainless steel. - Graphical abstract: Display Omitted - Highlights: • Extensive grain growth in the HAZ of austenitic stainless steel was observed. • Intensification of < 100 > orientated grains was observed adjacent to both fusion lines. • Annealing twins with Σ3 CSL boundaries were formed in the austenite of both HAZ. • Cub-on-cube OR was observed between austenite and ferrite in the weld

  4. Characterization of microstructure and texture across dissimilar super duplex/austenitic stainless steel weldment joint by austenitic filler metal

    Energy Technology Data Exchange (ETDEWEB)

    Eghlimi, Abbas, E-mail: a.eghlimi@ma.iut.ac.ir [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Shamanian, Morteza [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Eskandarian, Masoomeh [Department of Materials Engineering, Shiraz University, Shiraz 71348-51154 (Iran, Islamic Republic of); Zabolian, Azam [Department of Natural Resources, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Szpunar, Jerzy A. [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9 (Canada)

    2015-08-15

    The evolution of microstructure and texture across an as-welded dissimilar UNS S32750 super duplex/UNS S30403 austenitic stainless steel joint welded by UNS S30986 (AWS A5.9 ER309LMo) austenitic stainless steel filler metal using gas tungsten arc welding process was evaluated by optical micrography and EBSD techniques. Due to their fabrication through rolling process, both parent metals had texture components resulted from deformation and recrystallization. The weld metal showed the highest amount of residual strain and had large austenite grain colonies of similar orientations with little amounts of skeletal ferrite, both oriented preferentially in the < 001 > direction with cub-on-cube orientation relationship. While the super duplex stainless steel's heat affected zone contained higher ferrite than its parent metal, an excessive grain growth was observed at the austenitic stainless steel's counterpart. At both heat affected zones, austenite underwent some recrystallization and formed twin boundaries which led to an increase in the fraction of high angle boundaries as compared with the respective base metals. These regions showed the least amount of residual strain and highest amount of recrystallized austenite grains. Due to the static recrystallization, the fraction of low degree of fit (Σ) coincident site lattice boundaries, especially Σ3 boundaries, was increased in the austenitic stainless steel heat affected zone, while the formation of subgrains in the ferrite phase increased the content of < 5° low angle boundaries at that of the super duplex stainless steel. - Graphical abstract: Display Omitted - Highlights: • Extensive grain growth in the HAZ of austenitic stainless steel was observed. • Intensification of < 100 > orientated grains was observed adjacent to both fusion lines. • Annealing twins with Σ3 CSL boundaries were formed in the austenite of both HAZ. • Cub-on-cube OR was observed between austenite and ferrite in the weld

  5. Spontaneous and indicated preterm delivery risk is increased among overweight and obese women without prepregnancy chronic disease.

    Science.gov (United States)

    Kim, S S; Mendola, P; Zhu, Y; Hwang, B S; Grantz, K L

    2017-10-01

    To investigate the independent impact of prepregnancy obesity on preterm delivery among women without chronic diseases by gestational age, preterm category and parity. A retrospective cohort study. Data from the Consortium on Safe Labor (CSL) in the USA (2002-08). Singleton deliveries at ≥23 weeks of gestation in the CSL (43 200 nulliparas and 63 129 multiparas) with a prepregnancy body mass index (BMI) ≥18.5 kg/m 2 and without chronic diseases. Association of prepregnancy BMI and the risk of preterm delivery was examined using Poisson regression with normal weight as reference. Preterm deliveries were categorised by gestational age (extremely, very, moderate to late) and category (spontaneous, indicated, no recorded indication). Relative risk of spontaneous preterm delivery was increased for extremely preterm among obese nulliparas (1.26, 95% CI: 0.94-1.70 for overweight; 1.88, 95% CI: 1.30-2.71 for obese class I; 1.99, 95% CI: 1.32-3.01 for obese class II/III) and decreased for moderate to late preterm delivery among overweight and obese multiparas (0.90, 95% CI: 0.83-0.97 for overweight; 0.87, 95% CI: 0.78-0.97 for obese class I; 0.79, 95% CI: 0.69-0.90 for obese class II/III). Indicated preterm delivery risk was increased with prepregnancy BMI in a dose-response manner for extremely preterm and moderate to late preterm among nulliparas, as it was for moderate to late preterm delivery among multiparas. Prepregnancy BMI was associated with increased risk of preterm delivery even in the absence of chronic diseases, but the association was heterogeneous by preterm categories, gestational age and parity. Obese nulliparas without chronic disease had higher risk for spontaneous delivery <28 weeks of gestation. © 2017 Royal College of Obstetricians and Gynaecologists.

  6. An electron backscattered diffraction study on the dynamic recrystallization behavior of a nickel–chromium alloy (800H) during hot deformation

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Yu, E-mail: vieri32825@126.com [State Key Laboratory of Rolling and Automation, Northeastern University, Shenyang 110819 (China); Di, Hongshuang; Zhang, Jingqi; Zhang, Jiecen; Ma, Tianjun [State Key Laboratory of Rolling and Automation, Northeastern University, Shenyang 110819 (China); Misra, R.D.K. [Center for Structural and Functional Materials, University of Louisiana at Lafayette, P.O. Box 44130, LA 70503 (United States)

    2013-11-15

    The objective of the study described here is to evaluate the effect of temperature, strain rate, and strain on the microstructure of dynamically recrystallized nickel–chromium alloy (800H) subjected to hot compression over a wide range of strain rates. The microstructural evolution was studied by electron backscattered diffraction (EBSD) and the effect of adiabatic heating on hot deformation was analyzed to correct the flow curves at high strains. The grain orientation spread (GOS) approach was used to distinguish the dynamic recrystallization (DRX) grains from the deformed matrix. The nucleation mechanism of DRX and the role of Σ3{sup n} CSL boundaries during DRX were explored. Additionally, the influence of carbides on the DRX behavior was studied within the temperature of 850–950 °C. The results indicated that the DRX can be stimulated by adiabatic heating and strong dislocation–dislocation interaction occurring with increase in the strain rate in the range of 1–30 s{sup −1}. The threshold value of GOS (1.2°) separated the DRX grains from the deformed matrix. The recrystallized grains nucleated at pre-existing grain boundaries by extensive bulging associated with grain fragmentation. The Σ3{sup n} CSL boundaries play an important role in DRX and they can be generated through interaction among them after the initiation of DRX. The precipitation of Cr{sub 23}C{sub 6} and Ti(C, N) at the parent grain boundary could restrain or even inhibit the occurrence of DRX in the temperature range of 850–950 °C.

  7. Estimating the prevalence of comorbid conditions and their effect on health care costs in patients with diabetes mellitus in Switzerland

    Directory of Open Access Journals (Sweden)

    Huber CA

    2014-10-01

    Full Text Available Carola A Huber,1 Peter Diem,2 Matthias Schwenkglenks,3 Roland Rapold,1 Oliver Reich1 1Department of Health Sciences, Helsana Group, Zürich, Switzerland; 2Department of Endocrinology, Diabetes and Clinical Nutrition, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland; 3Institute of Social and Preventive Medicine, University of Zürich, Zürich, Switzerland Background: Estimating the prevalence of comorbidities and their associated costs in patients with diabetes is fundamental to optimizing health care management. This study assesses the prevalence and health care costs of comorbid conditions among patients with diabetes compared with patients without diabetes. Distinguishing potentially diabetes- and nondiabetes-related comorbidities in patients with diabetes, we also determined the most frequent chronic conditions and estimated their effect on costs across different health care settings in Switzerland. Methods: Using health care claims data from 2011, we calculated the prevalence and average health care costs of comorbidities among patients with and without diabetes in inpatient and outpatient settings. Patients with diabetes and comorbid conditions were identified using pharmacy-based cost groups. Generalized linear models with negative binomial distribution were used to analyze the effect of comorbidities on health care costs. Results: A total of 932,612 persons, including 50,751 patients with diabetes, were enrolled. The most frequent potentially diabetes- and nondiabetes-related comorbidities in patients older than 64 years were cardiovascular diseases (91%, rheumatologic conditions (55%, and hyperlipidemia (53%. The mean total health care costs for diabetes patients varied substantially by comorbidity status (US$3,203–$14,223. Patients with diabetes and more than two comorbidities incurred US$10,584 higher total costs than patients without comorbidity. Costs were significantly higher in patients with

  8. Computation of Estonian CORS data using Bernese 5.2 and Gipsy 6.4 softwares

    Science.gov (United States)

    Kollo, Karin; Kall, Tarmo; Liibusk, Aive

    2017-04-01

    GNSS permanent station network in Estonia (ESTREF) was established already in 2007. In 2014-15 extensive reconstruction of ESTREF was carried out, including the establishment of 18 new stations, change of the hardware in CORS stations as well as establishing GNSS-RTK service for the whole Estonia. For GNSS-RTK service one needs precise coordinates in well-defined reference frame, i.e., ETRS89. For long time stability of stations and time-series analysis the re-processing of Estonian CORS data is ongoing. We re-process data from 2007 until 2015 with program Bernese GNSS 5.2 (Dach, 2015). For the set of ESTREF stations established in 2007, we perform as well computations with GIPSY 6.4 software (Ries et al., 2015). In the computations daily GPS-only solution was used. For precise orbits, final products from CODE (CODE analysis centre at the Astronomical Institute of the University of Bern) and JPL (Jet Propulsion Laboratory) for Bernese and GIPSY solutions were used, respectively. The cut-off angle was set to 10 degrees in order to avoid near-field multipath influence. In GIPSY, precise point positioning method with fixing ambiguities was used. Bernese calculations were performed based on double difference processing. Antenna phase centers were modelled based on igs08.atx and epnc_08.atx files. Vienna mapping function was used for mapping tropospheric delays. For the GIPSY solution, the higher order ionospheric term was modelled based on IRI-2012b model. For the Bernese solution higher order ionospheric term was neglected. FES2004 ocean tide loading model was used for the both computation strategies. As a result, two solutions using different scientific GNSS computation programs were obtained. The results from Bernese and GIPSY solutions were compared, using station repeatability values, RMS and coordinate differences. KEYWORDS: GNSS reference station network, Bernese GNSS 5.2, Gipsy 6.4, Estonia. References: Dach, R., S. Lutz, P. Walser, P. Fridez (Eds); 2015

  9. Quantification of the cumulative effects of river training works on the basin scale with 2D flood modelling

    Science.gov (United States)

    Zischg, Andreas Paul; Felder, Guido; WWeingartner, Rolf

    2015-04-01

    The catchment of the river Aare upstream of Bern, Switzerland, with an area of approx. 3000 km2 is a complex network of sub-catchments with different runoff characteristics; it also includes two larger lakes. Most of the rivers were regulated in the 18th century. An important regulation, however, was realised as early as in the 17th century. For this catchment, the worst case flood event was identified and its consequences were analysed. Beside the hydro-meteorological characteristics, an important basis to model the worst case flood is to understand the non-linear effects of flood retention in the valley bottom and in the lakes. The aim of this study was to compare these effects based on both the current river network and the historic one prior to the main river training works. This allows to quantify the human impacts. Methodologically, we set up a coupled 2D flood model representing the floodplains of the river Aare as well as of the tributaries Lombach, Lütschine, Zulg, Rotache, Chise and Guerbe. The flood simulation was made in 2D with the software BASEMENT-ETH (Vetsch et al. 2014). The model was calibrated by means of reproducing the large floods in August 2005 and the bankfull discharge for all river reaches. The model computes the discharge at the outlet of the Aare catchment at Bern by routing all discharges from the sub-catchments through the river reaches and their floodplains. With this, the modulation of the input hydrographs by widespread floodings in the floodplains can be quantified. The same configuration was applied on the basis of reconstructed digital terrain models representing the landscape and the river network before the first significant river training works had been realised. This terrain model was reconstructed by georeferencing and digitalizing historic maps and cross-sections combined with the mapping of the geomorphologic evidences of former river structures in non-modified areas. The latter mapping procedure was facilitated by the

  10. [Jakob Klaesi on his 120th birthday].

    Science.gov (United States)

    Haenel, T

    2003-05-01

    Jakob Klaesi was born on the 29th May 1883 in Glarus Canton (Switzerland) and was assistant and later head physician at the Psychiatric University Hospital in Zurich, directed by Eugen Bleuler. Klaesi directed the new Psychiatric Outpatient Department in Basel from 1923 to 1926 and later founded the Schloss Kronau private clinic in the Zurich Canton. In 1933 he became director of the Psychiatric University Hospital in Bern. His attitude toward somatic treatment methods was skeptical, although about 1920 he founded a psychiatric sleep cure with Somnifen. Klaesi was primarily a psychotherapist and interested in the psychodynamics of his patients. With his great empathy, he was able to understand especially well their expressive behaviour. This capacity for empathy and his philosophic orientation enabled him to develop a phenomenological analysis of expression. He died on the 17th August 1980. Differences and parallels to the thinking of Alfred Adler and Karl Jaspers are discussed.

  11. [Albert-Jean-Louis Brun, pharmacist of Geneva and vulcanologist].

    Science.gov (United States)

    Chaigneau, M

    1996-01-01

    Albert-Jean-Louis Brun (1851-1929), was chemist of the University of Bern (Switzerland) and "licencié ès sciences" of the University of Sorbonne (France). In Paris he was a faithful follower of Charles Friedel. In Coutance (Genève), where he was working in his own chemistry, he realised all his researchs. After a trip to Stromboli in 1901, he studied the volcanic phenomena as a chemist, as a mineralogist and as a geophysicist. His researchs brought him till the mediterranean volcanos--Vesuve, Etna, Santorin--, till Java and Krakatoa, then Canarian islands, and the lava lake of Kilauea, etc. The results of his works are collected in a big book called "Recherches sur l'exhalaison volcanique": he presents a theory which was the subject of a polemic with the professor Henri Gautier of the professor Henri Gautier of the Faculty of Pharmacy of Paris.

  12. NATO Advanced Study Institute on Advances in the Computer Simulations of Liquid Crystals

    CERN Document Server

    Zannoni, Claudio

    2000-01-01

    Computer simulations provide an essential set of tools for understanding the macroscopic properties of liquid crystals and of their phase transitions in terms of molecular models. While simulations of liquid crystals are based on the same general Monte Carlo and molecular dynamics techniques as are used for other fluids, they present a number of specific problems and peculiarities connected to the intrinsic properties of these mesophases. The field of computer simulations of anisotropic fluids is interdisciplinary and is evolving very rapidly. The present volume covers a variety of techniques and model systems, from lattices to hard particle and Gay-Berne to atomistic, for thermotropics, lyotropics, and some biologically interesting liquid crystals. Contributions are written by an excellent panel of international lecturers and provides a timely account of the techniques and problems in the field.

  13. Genetic characterisation of the rabies virus vaccine strains used for oral immunization of foxes in Poland to estimate the effectiveness of vaccination.

    Science.gov (United States)

    Orłowska, Anna; Żmudziński, Jan Franciszek

    2015-02-01

    The main reservoir of rabies virus in Poland has been the red fox. To control rabies in wildlife, oral immunization of foxes was introduced in 1993. The vaccine is effective when it confers immunity against the virus circulating in the environment. To assess the above issue, a study of the molecular characteristics of 570-bp fragments of the N and G genes of vaccine strains SAD B19 and SAD Bern against street virus strains was performed. The results confirmed the similarity of the vaccine strains and rabies virus strains circulating in the environment and also demonstrate the genetic stability of vaccine strains that have been distributed in Poland for 20 years.

  14. The adventurous life of Friedrich Georg Houtermans, physicist (1903-1966)

    CERN Document Server

    Braccini, Saverio; Ereditato, Antonio; Scampoli, Paola

    2012-01-01

    The physicist Friedrich Houtermans (1903-1966) was an essential promoter and proponent of the development of physics in Berne. He introduced a number of activities in the field of elementary particles, with a special focus on the physics of cosmic rays, and important contributions in applied physics. This biography of Houtermans was written by Edoardo Amaldi and was almost finished just before his unexpected death in 1989. The editors have only corrected typographical errors and have introduced only minimal text changes in order to preserve the original content. Additionally they have collected and included unpublished pictures and memories from Houtermans’ students and collaborators. The text is the result of a thorough and intensive study on Houtermans’ life and character carried out by Edoardo Amaldi. It is more than a biography, since the figure of Houtermans is set in a historical perspective of Europe between the two world wars. This book will be of great interest to historians and historians of sci...

  15. Geology and Habitability of Terrestrial Planets

    CERN Document Server

    Fishbaugh, Kathryn E; Raulin, François; Marais, David J; Korablev, Oleg

    2007-01-01

    Given the fundamental importance of and universal interest in whether extraterrestrial life has developed or could eventually develop in our solar system and beyond, it is vital that an examination of planetary habitability goes beyond simple assumptions such as, "Where there is water, there is life." This book has resulted from a workshop at the International Space Science Institute (ISSI) in Bern, Switzerland (5-9 September 2005) that brought together planetary geologists, geophysicists, atmospheric scientists, and biologists to discuss the multi-faceted problem of how the habitability of a planet co-evolves with the geology of the surface and interior, the atmosphere, and the magnetosphere. Each of the six chapters has been written by authors with a range of expertise so that each chapter is itself multi-disciplinary, comprehensive, and accessible to scientists in all disciplines. These chapters delve into what life needs to exist and ultimately to thrive, the early environments of the young terrestrial pl...

  16. CERN Library | Edoardo Amaldi presents "The adventurous life of Friedrich Georg Houtermans, physicist (1903-1966)" | 11 November

    CERN Multimedia

    2014-01-01

    The physicist Friedrich Houtermans (1903-1966) was an important promoter and proponent of the development of physics in Berne. He introduced a number of activities in the field of elementary particles, with a special focus on the physics of cosmic rays, and made important contributions in applied physics.   This biography of Houtermans was written by Edoardo Amaldi and was almost finished just before his unexpected death in 1989. The editors have only corrected typographical errors and introduced minimal text changes in order to preserve the original content. Additionally they have collected and included previously unpublished pictures and memories from Houtermans’ students and collaborators.  The text is the result of a thorough and intensive study of Houtermans’ life and character carried out by Edoardo Amaldi. It is more than a biography, since the figure of Houtermans is set in a historical period in Europe between the two world wars. This book will be of great i...

  17. Bæredygtig transport

    DEFF Research Database (Denmark)

    Haas, Henning de; Søndergaard, Mads

    2009-01-01

    I denne artikel sættes fokus på bæredygtighed og transport. Baggrunden for artiklen er en undersøgelse af status for bæredygtig transport i et antal danske virksomheder i samarbejde med DHL. Indledningen giver en baggrund for fokus på bæredygtighed, efterfølgende sættes der fokus på "Green SCM......" for at afklare hvad det indeholder, definitioner mv. Dette er udgangspunktet for en præsentation af resultaterne fra undersøgelsen af bæredygtig transport. Undersøgelsen opsummeres og leder frem til en række implikationer for henholdsvis kunder (transportkøberne) og transportleverandørerne....

  18. Preliminary Information on the Vertebrate Fauna (Animalia: Vertebrata of the NATURA2000 Site “Rice Fields Tsalapitsa” (Bulgaria

    Directory of Open Access Journals (Sweden)

    Ivayla L. Klimentova

    2011-12-01

    Full Text Available The study was carried out by tree visits in different areas of the Natura 2000 site “Rice Fields Tsalapitsa” BG 0002086 (West of Plovdiv city, near village of Tsalapitsa. Our preliminary research showed that in the area vertebrates with high conservation status occurred included in the Bulgarian Bidiversity Act, Appendix II and III, Appendix II of the Bern convention, Natura 2000 species list, the Bonn convention, Appendix II, the Convention of the International Trade of Endangered Species, and the list of the International Union for Conservation of the Nature. This information will help in future preparation of the management plan of the Natura 2000 site and showed the need of studies focused on such areas which will help undertaking adequate measures for their proper way of conservation.

  19. Solar Variability and Planetary Climates

    CERN Document Server

    Calisesi, Y; Gray, L; Langen, J; Lockwood, M

    2007-01-01

    Variations in solar activity, as revealed by variations in the number of sunspots, have been observed since ancient times. To what extent changes in the solar output may affect planetary climates, though, remains today more than ever a subject of controversy. In 2000, the SSSI volume on Solar Variability and Climate reviewed the to-date understanding of the physics of solar variability and of the associated climate response. The present volume on Solar Variability and Planetary Climates provides an overview of recent advances in this field, with particular focus at the Earth's middle and lower atmosphere. The book structure mirrors that of the ISSI workshop held in Bern in June 2005, the collection of invited workshop contributions and of complementary introductory papers synthesizing the current understanding in key research areas such as middle atmospheric processes, stratosphere-troposphere dynamical coupling, tropospheric aerosols chemistry, solar storm influences, solar variability physics, and terrestri...

  20. Une grève sur la Toile.

    Directory of Open Access Journals (Sweden)

    Patrick Rérat

    2007-03-01

    Full Text Available La Suisse est un pays réputé pour sa paix du travail. Les rapports peu conflictuels entre les partenaires sociaux sont considérés comme faisant partie intégrante de ses avantages comparatifs. Dès lors, toute grève y fait figure de phénomène inhabituel. C’est le cas des événements qui se sont déroulés à l’usine Swissmetal Boillat (appelée familièrement « la Boillat » du nom de son fondateur, située à Reconvilier dans la partie francophone du canton de Berne. Ce ...