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  1. Wits Post Graduate Symposium Poster - iGEM

    CSIR Research Space (South Africa)

    Millroy, L

    2010-08-01

    Full Text Available This document is a poster providing details of the 2010 International Genetically Engineered Machines (iGEM) competition. The origins of the competition, as well as criteria, judging, sponsors, topic and team, are briefly described....

  2. International Genetically Engineered Machine (iGEM) Competition

    CSIR Research Space (South Africa)

    Sparrow, RW

    2010-07-01

    Full Text Available . At this meeting it was requested that the CSIR act as the administrative co-ordinating arm of the team. Following from this meeting a brochure was produced advertising the iGEM competition inside Wits and for Honours student nominations to be team members.... The academic year in South Africa commences in February. By late February 2010 student nominations had been received from which the supervisors selected the team members. The first team meeting was held on 5th March 2010. After which the team...

  3. The MCU-RFFI Monte Carlo code for reactor design applications

    International Nuclear Information System (INIS)

    Gomin, E.A.; Maiorov, L.V.

    1995-01-01

    MCU-RFFI is a general-purpose, continuous-energy, general geometry Monte Carlo code for solving external source or criticality problems for neutron transport in the energy range of 20 MeV to 10 -5 eV. The main fields of MCU-RFFI applications are as follows: (a) nuclear data validation; (b) design calculations (space reactors and other); (c) verification of design codes. MCU-RFFI is also supplied with tools to check the accuracy of design codes. These tools permit the user to calculate: the few group parameters of reactor cells, including the diffusion coefficients defined in a variety of ways, reaction rates for various nuclei, energy and space bins, and the kinetic parameters of systems, taking into account delayed neutrons. Boundary conditions include vacuum, white and specular reflection, and the condition of translational symmetry. The criticals with the neutron leakage given by the buckling vector may be calculated by solving Benoist's problem. The curve of criticality coefficient dependence on buckling may be determined during the single code run and critical buckling may be determined. Double heterogeneous systems with fuel elements containing many thousands of spherical microcells can be solved

  4. Promoting microbiology education through the iGEM synthetic biology competition.

    Science.gov (United States)

    Kelwick, Richard; Bowater, Laura; Yeoman, Kay H; Bowater, Richard P

    2015-08-01

    Synthetic biology has developed rapidly in the 21st century. It covers a range of scientific disciplines that incorporate principles from engineering to take advantage of and improve biological systems, often applied to specific problems. Methods important in this subject area include the systematic design and testing of biological systems and, here, we describe how synthetic biology projects frequently develop microbiology skills and education. Synthetic biology research has huge potential in biotechnology and medicine, which brings important ethical and moral issues to address, offering learning opportunities about the wider impact of microbiological research. Synthetic biology projects have developed into wide-ranging training and educational experiences through iGEM, the International Genetically Engineered Machines competition. Elements of the competition are judged against specific criteria and teams can win medals and prizes across several categories. Collaboration is an important element of iGEM, and all DNA constructs synthesized by iGEM teams are made available to all researchers through the Registry for Standard Biological Parts. An overview of microbiological developments in the iGEM competition is provided. This review is targeted at educators that focus on microbiology and synthetic biology, but will also be of value to undergraduate and postgraduate students with an interest in this exciting subject area. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

    DEFF Research Database (Denmark)

    Pedersen, Nancy L; Christensen, Kaare; Dahl, Anna K

    2013-01-01

    The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from ove...

  6. Impacts of Groundwater on the Atmospheric Convection in Amazon using Multi-GCM Simulations from I-GEM project

    Science.gov (United States)

    Lo, M. H.; Chien, R. Y.; Ducharne, A.; Decharme, B.; Lan, C. W.; Wang, F.; Cheruy, F.; Colin, J.

    2017-12-01

    Previous research indicated that groundwater plays an important role in hydrological cycle and is a major source of water vapor in climate models, which may result in modifications of atmospheric convection. For instance, our previous study showed that when considering the groundwater dynamics in a GCM, the wet soil induced surface cooling effect can further reduce the Amazon dry season convection and precipitation. However, the main mechanisms of the interaction among groundwater, soil moisture, and precipitation are still unclear, and they need to be examined in several climate models. In this study, we further examine the influence of the surface cooling effects due to the groundwater on the convection over the Amazon. To this end, we use idealized simulations of the IGEM (Impact of Groundwater in Earth system Models) project, with 3 GCMs (CESM, CNRM, and IPSL): in each of them, we prescribed a water table at a constant depth throughout all land areas, to create globally wet conditions. Preliminary analysis shows a contradict result of the tendency of precipitation in the three models with wet condition which indicates a great uncertainty of the groundwater's impacts in coupled GCMs.

  7. Mapping fields of 137Cs contamination in soils in the context of their stability and hierarchical spatial structure

    Science.gov (United States)

    Korobova, E.; Romanov, S.

    2009-04-01

    measurement of the specimen for radioecological monitoring. UkrNIISKHR, Kiev. 2. Korobova, E.M., Romanov, S.L., Samsonov, V.L., Kirov, S.S., 2006. Experimental study of spatial 137Cs redistribution in paragenetic elementary landscapes, in: Kasimov, N.S. et al (Eds.), Geochemistry of biosphere (devoted to 90-th anniversary of A.I. Perelman), MSU, IGEM, RFFI, Moscow-Smolensk, pp.157-159. 3. Linnik, V.G., Saveliev, A.A., Govorun, A.P., Ivanitsky, O.M., Sokolov, A.V., 2006. Analysis of the Cs-137 contamination field on micro-landscape scale within the virgin meadows in the western part of the Bryansk region, in: Kasimov, N.S. et al (Eds.), Geochemistry of biosphere (devoted to 90-th anniversary of A.I. Perelman), MSU, IGEM, RFFI, Moscow-Smolensk, pp. 201-204. 4. Samsonova V.P. Spatial variability of the soil parameters. On example of soddy-podozolic soils. Moscow, LKI, 2008, 156 p. 5.Shcheglov, A.I., Tsvetnova, O.B., Klyashtorin, A.I., 2001. Biogeochemical migration of technogenic radionuclides in forest ecosystems. Nauka, Moscow.

  8. Accuracy of WWR-M criticality calculations with code MCU-RFFI

    International Nuclear Information System (INIS)

    Petrov, Yu.V.; Erykalov, A.N.; Onegin, M.S.

    1999-01-01

    The scattering and deviation of fuel element parameters by manufacturing, approximations of the reactor structure in the computer model, the partly inadequate neutron cross sections in the computer codes etc. lead to a discrepancy between the reactivity computations and data. We have compared reactivity calculations using the MCU-RRFI Monte Carlo code of critical assemblies containing WWR-M2 (36 enriched) an WWR-M5 (90%) fuel elements with benchmark experiments. The agreement was about Δρ≅±0.3%. A strong influence of the water ratio on reactivity was shown and a significant heterogeneous effect was found. We have also investigated, by full scale reactor calculations for the RETR program, the contribution to the reactivity of the main reactor structure elements: beryllium reflector, experimental channels irradiation devices inside the core, etc. Calculations show the importance of a more thorough study of the contributions of products of the (n, α) reaction in the Be reflector to the reactivity. Ways of improving the accuracy of the calculations are discussed. (author)

  9. Accuracy of WWR-M criticality calculations with code MCU-RFFI

    Energy Technology Data Exchange (ETDEWEB)

    Petrov, Yu V [Petersburg Nuclear Physics Institute RAS, 188350 Gatchina, St. Petersburg (Russian Federation); Erykalov, A N; Onegin, M S [Petersburg Nuclear Physics Institute RAS, 188350 Gatchina, St. Petersburg (Russian Federation)

    1999-10-01

    The scattering and deviation of fuel element parameters by manufacturing, approximations of the reactor structure in the computer model, the partly inadequate neutron cross sections in the computer codes etc. lead to a discrepancy between the reactivity computations and data. We have compared reactivity calculations using the MCU-RRFI Monte Carlo code of critical assemblies containing WWR-M2 (36 enriched) an WWR-M5 (90%) fuel elements with benchmark experiments. The agreement was about {delta}{rho}{approx_equal}{+-}0.3%. A strong influence of the water ratio on reactivity was shown and a significant heterogeneous effect was found. We have also investigated, by full scale reactor calculations for the RETR program, the contribution to the reactivity of the main reactor structure elements: beryllium reflector, experimental channels irradiation devices inside the core, etc. Calculations show the importance of a more thorough study of the contributions of products of the (n, {alpha}) reaction in the Be reflector to the reactivity. Ways of improving the accuracy of the calculations are discussed. (author)

  10. 76 FR 42706 - Amendment of Inspector General Operations & Reporting System Audit, Assignment, and Timesheet...

    Science.gov (United States)

    2011-07-19

    ... Operations & Reporting System Audit, Assignment, and Timesheet Files (EPA-42) AGENCY: Environmental... (IGOR) System Audit, Assignment, and Timesheet Files (EPA-42) to the Inspector General Enterprise Management System (IGEMS) Audit, Assignment, and Timesheet Modules. DATES: Effective Dates: Persons wishing...

  11. On Beyond Star Trek, the Role of Synthetic Biology in Nasa's Missions

    Science.gov (United States)

    Rothschild, Lynn J.

    2016-01-01

    The time has come to for NASA to exploit the nascent field of synthetic biology in pursuit of its mission, including aeronautics, earth science, astrobiology and notably, human exploration. Conversely, NASA advances the fundamental technology of synthetic biology as no one else can because of its unique expertise in the origin of life and life in extreme environments, including the potential for alternate life forms. This enables unique, creative "game changing" advances. NASA's requirement for minimizing upmass in flight will also drive the field toward miniaturization and automation. These drivers will greatly increase the utility of synthetic biology solutions for military, health in remote areas and commercial purposes. To this end, we have begun a program at NASA to explore the use of synthetic biology in NASA's missions, particularly space exploration. As part of this program, we began hosting an iGEM team of undergraduates drawn from Brown and Stanford Universities to conduct synthetic biology research at NASA Ames Research Center. The 2011 team (http://2011.igem.org/Team:Brown-Stanford) produced an award-winning project on using synthetic biology as a basis for a human Mars settlement and the 2012 team has expanded the use of synthetic biology to estimate the potential for life in the clouds of other planets (http://2012.igem.org/Team:Stanford-Brown; http://www.calacademy.org/sciencetoday/igem-competition/). More recent projects from the Stanford-Brown team have expanded our ideas of how synthetic biology can aid NASA's missions from "Synthetic BioCommunication" (http://2013.igem.org/Team:Stanford-Brown) to a "Biodegradable UAS (drone)" in collaboration with Spelman College (http://2014.igem.org/Team:StanfordBrownSpelman#SBS%20iGEM) and most recently, "Self-Folding Origami" (http://2015.igem.org/Team:Stanford-Brown), the winner of the 2015 award for Manufacturing.

  12. Pedogennyje i litogennyje osobennosti mineralogičeskogo sostava černozema na krasnocvetnych porodach

    Czech Academy of Sciences Publication Activity Database

    Lesovaja, S. N.; Kapička, Aleš; Petrovský, Eduard; Aparin, B. F.

    2003-01-01

    Roč. 36, č. 12 (2003), s. 1482-1490 ISSN 0032-180X Grant - others:RFFI(RU) 01-04-48815 Institutional research plan: CEZ:AV0Z3012916 Keywords : mineralogical composition * chernozem * magnetic minerals Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  13. Pedogenic and lithogenic features in the mineralogical composition of chernozem developed from red-earth deposits

    Czech Academy of Sciences Publication Activity Database

    Lesovaya, S. N.; Kapička, Aleš; Petrovský, Eduard; Aparin, B. F.

    2003-01-01

    Roč. 36, č. 12 (2003), s. 1325-1333 ISSN 1064-2293 Grant - others:RFFI(RU) 01-04-48815 Institutional research plan: CEZ:AV0Z3012916 Keywords : mineralogical composition * chernozem * magnetic minerals Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 0.136, year: 2003

  14. Dvizhenie aerozoľnoi kapli v termodiffuzionnoi kamere

    Czech Academy of Sciences Publication Activity Database

    Bakanov, S. P.; Ždímal, Vladimír; Zaripov, Sh. KH.; Smolík, Jiří

    2002-01-01

    Roč. 66, č. 1 (2002), s. 95-101 R&D Projects: GA ČR GA104/97/1198 Grant - others:RFFI(RU) 99-01-00169 Keywords : aerosol particle * thermal diffusion * cloud chamber Subject RIV: CI - Industrial Chemistry, Chemical Engineering

  15. Gender Differences in Marital Status Moderation of Genetic and Environmental Influences on Subjective Health

    DEFF Research Database (Denmark)

    Finkel, Deborah; Franz, Carol E; Horwitz, Briana

    2016-01-01

    From the IGEMS Consortium, data were available from 26,579 individuals aged 23 to 102 years on 3 subjective health items: self-rated health (SRH), health compared to others (COMP), and impact of health on activities (ACT). Marital status was a marker of environmental resources that may moderate...

  16. Experiential Engineering through iGEM--An Undergraduate Summer Competition in Synthetic Biology

    Science.gov (United States)

    Mitchell, Rudolph; Dori, Yehudit Judy; Kuldell, Natalie H.

    2011-01-01

    Unlike students in other engineering disciplines, undergraduates in biological engineering typically have limited opportunity to develop design competencies, and even fewer chances to implement their designed projects. The international Genetically Engineered Machines (iGEM) competition is a student Synthetic Biology competition that, in 2009,…

  17. Engineering a Biological Revolution.

    Science.gov (United States)

    Matheson, Susan

    2017-01-26

    The new field of synthetic biology promises to change health care, computer technology, the production of biofuels, and more. Students participating in the International Genetically Engineered Machine (iGEM) competition are on the front lines of this revolution. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. A molecular computer to classify cells

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    If only we had a small molecular computer to leverage this disparity, programmable to optimally recognize different classes of cells and, once inside a target cell, to execute an action. Like what a student team researched for this year's synthetic biology iGEM competition.

  19. The structural effects of cap and trade climate policy

    International Nuclear Information System (INIS)

    Goettle, Richard J.; Fawcett, Allen A.

    2009-01-01

    The Inter-temporal General Equilibrium Model (IGEM) explores the cost to the U.S. economy of increasingly more stringent cap and trade regimes. The economy-wide losses are small with energy, agriculture, chemicals, high tech manufacturing and trade being most affected. The availability of lower cost offsets substantially reduces these economic losses. The economy becomes less capital but more labor intensive. Household welfare losses are smaller for full consumption (goods, services and leisure). A more inelastic trade-off between consumption and leisure dramatically reduces policy costs as do more favorable revenue recycling options. Induced technical change yields a small, measurable reduction in policy costs. (author)

  20. Plug ‘n’ Play with DNA

    DEFF Research Database (Denmark)

    Lund, Anne Mathilde; Andreasen, Elisa W.; Korgaard, Jaide V.

    Synthetic biology has evolved dramatically within the past decade, which calls for a revolution of the Standard Assembly method that makes the foundation of BioBricks. We believe that iGEM should be about fast assembly of BioBricks, where any thinkable part, device or existing BioBrick can be com...... be combined for any type of organism within one day. Therefore, we have designed a new BioBrick Kit based on a novel assembly standard; called “Plug 'n' Play with DNA”....

  1. The Role of Synthetic Biology in NASA's Missions

    Science.gov (United States)

    Rothschild, Lynn J.

    2016-01-01

    The time has come to for NASA to exploit synthetic biology in pursuit of its missions, including aeronautics, earth science, astrobiology and most notably, human exploration. Conversely, NASA advances the fundamental technology of synthetic biology as no one else can because of its unique expertise in the origin of life and life in extreme environments, including the potential for alternate life forms. This enables unique, creative "game changing" advances. NASA's requirement for minimizing upmass in flight will also drive the field toward miniaturization and automation. These drivers will greatly increase the utility of synthetic biology solutions for military, health in remote areas and commercial purposes. To this end, we have begun a program at NASA to explore the use of synthetic biology in NASA's missions, particular space exploration. As part of this program, we began hosting an iGEM team of undergraduates drawn from Brown and Stanford Universities to conduct synthetic biology research at NASA Ames Research Center. The 2011 team (http://2011.igem.org/Team:Brown-Stanford) produced an award-winning project on using synthetic biology as a basis for a human Mars settlement.

  2. The use of the codes from MCU family for calculations of WWER type reactors

    International Nuclear Information System (INIS)

    Abagijan, L.P.; Alexeyev, N.I.; Bryzgalov, V.I.; Gomin, E.A.; Glushkov, A.E.; Gorodkov, S.S.; Gurevich, M.I.; Kalugin, M.A.; Marin, S.V.; Shkarovsky, D.A.; Yudkevich, M.S.

    2000-01-01

    The MCU-RFFI/A and MCU-REA codes developed within the framework of the long term MCU project are widely used for calculations of neutron physic characteristics of WWER type reactors. Complete descriptions of the codes are available in both Russian and English. The codes are verified and validated by means of the comparison of calculated results with experimental data and mathematical benchmarks. The codes are licensed by Russian Nuclear and Criticality Safety Regulatory Body (Gosatomnadzor RF) (Code Passports: N 61 of 17.10.1966 and N 115 of 02.03.2000 accordingly)). The report gives examples of WWER reactor physic tasks important for practice solved using the codes from the MCU family. Some calculational results are given too. (Authors)

  3. The EOS studies on Luch facility

    International Nuclear Information System (INIS)

    Bel'kov, S.A.; Voronich, I.N.; Garanin, S.G.; Derkach, V.N.; Kochemasov, G.G.; Litvin, D.N.; Sukharev, S.A.

    2010-01-01

    Complete text of publication follows. The results of the investigations in the shock compressibility of materials on the 'Luch' facility are presented. The experiments have been performed with impedance mismatch technique applying. The output non-uniformity of the shocks achieved < 10 ps and inaccuracy of their velocity measuring < 3%. The pressures to 30 Mbars were developed in lead and till 50 Mbars with applying of the special-constructed targets for hydrodynamic pressure increasing. Results on the materials shock compressibility have been obtained that accord well with the test results shown on hydrodynamic stands. The work was performed in part under the sponsorship of the RFFI (grants No. 09-02-12157-ofi-m and No. 09-02-97089-r povolzh'ye-a), and grant of the President of the RF to leading scientific schools No. 65192.2010.2.

  4. Gender Differences in Marital Status Moderation of Genetic and Environmental Influences on Subjective Health.

    Science.gov (United States)

    Finkel, Deborah; Franz, Carol E; Horwitz, Briana; Christensen, Kaare; Gatz, Margaret; Johnson, Wendy; Kaprio, Jaako; Korhonen, Tellervo; Niederheiser, Jenae; Petersen, Inge; Rose, Richard J; Silventoinen, Karri

    2015-10-14

    From the IGEMS Consortium, data were available from 26,579 individuals aged 23 to 102 years on 3 subjective health items: self-rated health (SRH), health compared to others (COMP), and impact of health on activities (ACT). Marital status was a marker of environmental resources that may moderate genetic and environmental influences on subjective health. Results differed for the 3 subjective health items, indicating that they do not tap the same construct. Although there was little impact of marital status on variance components for women, marital status was a significant modifier of variance in all 3 subjective health measures for men. For both SRH and ACT, single men demonstrated greater shared and nonshared environmental variance than married men. For the COMP variable, genetic variance was greater for single men vs. married men. Results suggest gender differences in the role of marriage as a source of resources that are associated with subjective health.

  5. Synthetic biology: Emerging bioengineering in Indonesia

    Science.gov (United States)

    Suhandono, Sony

    2017-05-01

    The development of synthetic biology will shape the new era of science and technology. It is an emerging bioengineering technique involving genetic engineering which can alter the phenotype and behavior of the cell or the new product. Synthetic biology may produce biomaterials, drugs, vaccines, biosensors, and even a recombinant secondary metabolite used in herbal and complementary medicine, such as artemisinin, a malaria drug which is usually extracted from the plant Artemisia annua. The power of synthetic biology has encouraged scientists in Indonesia, and is still in early development. This paper also covers some research from an Indonesian research institute in synthetic biology such as observing the production of bio surfactants and the enhanced production of artemisinin using a transient expression system. Synthetic biology development in Indonesia may also be related to the iGEM competition, a large synthetic biology research competition which was attended by several universities in Indonesia. The application of synthetic biology for drug discovery will be discussed.

  6. Gene-environment interplay in depressive symptoms

    DEFF Research Database (Denmark)

    Petkus, A. J.; Beam, C. R.; Johnson, W.

    2017-01-01

    that genetic factors play a larger part in the association between depressive symptoms and physical illness for men than for women. For both sexes, across all ages, physical illness may similarly trigger social and health limitations that contribute to depressive symptoms.......Background Numerous factors influence late-life depressive symptoms in adults, many not thoroughly characterized. We addressed whether genetic and environmental influences on depressive symptoms differed by age, sex, and physical illness. Method The analysis sample included 24 436 twins aged 40......-90 years drawn from the Interplay of Genes and Environment across Multiple Studies (IGEMS) Consortium. Biometric analyses tested age, sex, and physical illness moderation of genetic and environmental variance in depressive symptoms. Results Women reported greater depressive symptoms than men. After age 60...

  7. Engineering control of bacterial cellulose production using a genetic toolkit and a new cellulose-producing strain

    Science.gov (United States)

    Florea, Michael; Hagemann, Henrik; Santosa, Gabriella; Micklem, Chris N.; Spencer-Milnes, Xenia; de Arroyo Garcia, Laura; Paschou, Despoina; Lazenbatt, Christopher; Kong, Deze; Chughtai, Haroon; Jensen, Kirsten; Freemont, Paul S.; Kitney, Richard; Reeve, Benjamin; Ellis, Tom

    2016-01-01

    Bacterial cellulose is a strong and ultrapure form of cellulose produced naturally by several species of the Acetobacteraceae. Its high strength, purity, and biocompatibility make it of great interest to materials science; however, precise control of its biosynthesis has remained a challenge for biotechnology. Here we isolate a strain of Komagataeibacter rhaeticus (K. rhaeticus iGEM) that can produce cellulose at high yields, grow in low-nitrogen conditions, and is highly resistant to toxic chemicals. We achieved external control over its bacterial cellulose production through development of a modular genetic toolkit that enables rational reprogramming of the cell. To further its use as an organism for biotechnology, we sequenced its genome and demonstrate genetic circuits that enable functionalization and patterning of heterologous gene expression within the cellulose matrix. This work lays the foundations for using genetic engineering to produce cellulose-based materials, with numerous applications in basic science, materials engineering, and biotechnology. PMID:27247386

  8. Synthetic biology: engineering molecular computers

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Complicated systems cannot survive the rigors of a chaotic environment, without balancing mechanisms that sense, decide upon and counteract the exerted disturbances. Especially so with living organisms, forced by competition to incredible complexities, escalating also their self-controlling plight. Therefore, they compute. Can we harness biological mechanisms to create artificial computing systems? Biology offers several levels of design abstraction: molecular machines, cells, organisms... ranging from the more easily-defined to the more inherently complex. At the bottom of this stack we find the nucleic acids, RNA and DNA, with their digital structure and relatively precise interactions. They are central enablers of designing artificial biological systems, in the confluence of engineering and biology, that we call Synthetic biology. In the first part, let us follow their trail towards an overview of building computing machines with molecules -- and in the second part, take the case study of iGEM Greece 201...

  9. NDA (Non Destructive Assay) measurements for isotopic homogeneity of UO2 powder form mechanical blending and results comparison between gamma and mass spectrometry

    International Nuclear Information System (INIS)

    Rojas, Carlos A.; Rojo, Marcelo

    2005-01-01

    Eight batches of 0.95% UO2 powder, obtained by mechanical blending of 3.5% and 0.711 % UO2 powders, were sampled. From each batch, samples at the top and the bottom from four drums were taken. Each sample was analysed using different measurement systems, two with NaI(Tl) detectors and another two with HPGe detectors. The Mini Multichannel Analyser (MMCA), model GBS 166, and the calculation codes NaIGEM and MEGAU-EM for peak area analysis and enrichment determination were used. For all cases the WinSPEC acquisition code was used. From the statistical analysis of the measurement results it arises that it is possible to determine the homogeneity grade of UO2 powder samples with a lower error than 0.5% for both types of detectors. The performance of the HPGe measurement system is only slightly more precise than the NaI system. (author)

  10. A neutronic feasibility study for LEU conversion of the WWR-M reactor at Gatchina

    International Nuclear Information System (INIS)

    Petrov, Yu. V.; Erykalov, A.N.; Onegin, M.S.

    2000-01-01

    In this report we present the results of computations of the full scale reactor core with HEU (90%), MEU (36%) and LEU (19.75%) fuel. The reactor computer model for the MCU RFFI Monte Carlo code includes all peculiarities of the core. Calculations show that a uranium density of 3.3gU/cm 3 of MEU (36%) fuel and 8/25gU/cm 3 of LEU (19.75%) in WWR-M5 fuel assembly (FA) geometry is required to match the fuel cycle length of the HEU (90%) case with the same end of cycle (EOEC) excess reactivity. For the equilibrium fuel cycle the fuel burnup and poisoning, the fast and thermal neutron fluxes, the reactivity worth of control rods were calculated for the reference case with HEU (90%) FA and for the MEU and LEU FA. The relative accuracy of this neutronic feasibility study of fuel enrichment reduction of the WWR-M reactor in Gatchina is sufficient to start the fabrication feasibility study of MEU (36%) WWR-M5 fuel assemblies. At the present stage of technology it seems hardly possible to manufacture LEU (19.75%) fuel elements in WWR-M5 geometry due to too high uranium density. Only a future R and D can solve the problem. (author)

  11. Otolith mass asymmetry: natural, and after weightlessness and hypergravity

    Science.gov (United States)

    Lychakov, Dmitri

    It is believed that otolith mass asymmetry (OA) can play an essential role in genesis of vestibular space disturbances in human subjects and fish. This review poster presents data on values and characters of OA in animals of various species and classes and on the effect of weightlessness and hypergravity on OA; the issue of the effect of OA on vestibular and auditory functions also is considered (Lychakov, Rebane, 2004, 2005; Lychakov et al., 2006, 2008). In symmetric vertebrates, OA was shown to be fluctuating, its coefficient chiχ ranges from - 0.2 to + 0.2 (±± 20%). It should be stressed that in the overwhelming majority of individuals absolute values of chiχ selection. Unlike symmetric vertebrates, labyrinths of many Pleuronectiformes have pronounced OA. Otoliths in the lower labyrinth, on average, are significantly heavier than those in the upper labyrinth. The organs of flatfish represent the only example when OA, being directional, seem to play an essential role in lateralized behavior and are suggested to be used in the spatial localization of the source of sound. The short-term weightlessness and relatively weak hypergravity (> 3g as well as some diseases and age-related changes can indirectly enhance OA and cause some functional disturbances. This work was partly supported by Russian grant RFFI 14-04-00601.

  12. Development of the systems for uniform target irradiation

    International Nuclear Information System (INIS)

    Voronin, A.Yu.; Garanin, S.G.; Derkach, V.N.; Zhidkov, N.V.; Kravchenko, A.G.; Petrazhitskaya, N.A.; Starodubtsev, K.V.; Sukharev, S.A.; Shnyagin, R.A.

    2010-01-01

    Complete text of publication follows. The new devices have been developed for laser beams homogenizing in the focal spot - multi-component lens raster and raster with the edges smoothing phase mask. The envelope non-uniformity of -4 radians. Investigation into the temporary-spatial smoothing with the use of low-density foams with the density less than the critical one is still in progress. Experiments on the foams with the density of 1-2.3 mg/cm 3 , thickness of 100-200 μm, and the cells' sizes up to the tens of micrometers were carried out with the radiation wavelength of 0.657 μm. The RMS non-uniformity < 5% has been found for the beam passed through the foam. The non-uniformity is evenly distributed over the spatial frequency spectrum. The induced divergence of radiation is measured to be 0.35 radian. The frequency of the rearranged speckled field of about 2 THz was obtained. The beam smoothing was recorded from the start of pulse of radiation, had the duration up to 1 ns, and the width of the radiation spectrum was about 30 A. The work was performed in part under the sponsorship of the RFFI (grants No. 09-02-12157-ofi-m and No. 09-02-97095-r-povolzh'ye-a) and grant of the President of the RF to leading scientific schools No. 65192.2010.2.

  13. Mathematical model of rhamnolipid production using E.coli bacteria

    Science.gov (United States)

    Adham, Muhammad Fariduddin; Apri, Mochamad; Moeis, Maelita Ramdani

    2018-03-01

    Rhamnolipid is one of biosurfactants that is widely used in many industries. Despite its wide use, production of rhamnolipid usually involves a pathogen that may endanger our health. To tackle this issue, in iGEM (International Genetically Engineered Machine) competition 2015, our team engineered Escherichia coli (E.coli) to produce rhamnolipid. The bacteria were then put into medium containing glucose and lactose. It turned out that bacteria E. coli produced lower rhamnolipid than that by pseudomonas, therefore a good strategy is required to improve their productivity. We present a mathematical model to describe the production of rhamnolipid by the engineered E coli. Using bifurcation analysis, the equilibrium points of the model and their stabilities were analyzed as the amount of lactose was varied. We show that the system produces bistability behavior for some interval values of lactose. From this analysis we found that to guarantee a high production of rhamnolipid, a high level of lactose is required. To maintain the productivity, however, it is sufficient to maintain the lactose level above a certain threshold value.

  14. Gene-environment interplay in depressive symptoms: moderation by age, sex, and physical illness.

    Science.gov (United States)

    Petkus, A J; Beam, C R; Johnson, W; Kaprio, J; Korhonen, T; McGue, M; Neiderhiser, J M; Pedersen, N L; Reynolds, C A; Gatz, M

    2017-07-01

    Numerous factors influence late-life depressive symptoms in adults, many not thoroughly characterized. We addressed whether genetic and environmental influences on depressive symptoms differed by age, sex, and physical illness. The analysis sample included 24 436 twins aged 40-90 years drawn from the Interplay of Genes and Environment across Multiple Studies (IGEMS) Consortium. Biometric analyses tested age, sex, and physical illness moderation of genetic and environmental variance in depressive symptoms. Women reported greater depressive symptoms than men. After age 60, there was an accelerating increase in depressive symptom scores with age, but this did not appreciably affect genetic and environmental variances. Overlap in genetic influences between physical illness and depressive symptoms was greater in men than in women. Additionally, in men extent of overlap was greater with worse physical illness (the genetic correlation ranged from near 0.00 for the least physical illness to nearly 0.60 with physical illness 2 s.d. above the mean). For men and women, the same environmental factors that influenced depressive symptoms also influenced physical illness. Findings suggested that genetic factors play a larger part in the association between depressive symptoms and physical illness for men than for women. For both sexes, across all ages, physical illness may similarly trigger social and health limitations that contribute to depressive symptoms.

  15. Immobilization of uranium and plutonium into boro-basalt, pyroxene and andradite mineral-like compositions

    International Nuclear Information System (INIS)

    Matyunin, Y.I.; Smelova, T.V.

    2000-01-01

    The immobilization of plutonium-containing wastes with the manufacturing of stable solid compositions is one of the problems that should be solved in the disposal of radioactive wastes. The works on the choice, preparation with the use of the cold crucible induction melter (CCIM) technology, and investigation of materials that are most suitable for immobilizing plutonium-containing wastes of different origin have been carried out at the All-Russian Scientific Research Institute of Inorganic Materials (VNIINM) and the Institute of the Geology of Ore Deposits, Petrography, Mineralogy, and Geochemistry (IGEM), Russian Academy of Sciences in the framework of the agreements with Lawrence Livermore National Laboratory (LLNL, USA) on the material and technical support. This paper presents the data on the synthesis of cerium-, uranium-, and plutonium-containing materials based on boro-basalt, pyroxene, and andradite compositions in the muffle furnace and by using the CCIM method. The compositions containing up to 15 - 18 wt % cerium oxide, 8 - 11 wt % uranium oxide, and 4.6 - 5.7 wt % plutonium oxide were obtained in laboratory facilities installed in glove boxes. Comparison studies of the materials synthesized in the muffle furnace and CCIM demonstrate the advantages of using the CCIM method. The distribution of components in the materials synthesized are investigated, and their certain physicochemical properties are determined. (authors)

  16. A multi-platform flow device for microbial (co- cultivation and microscopic analysis.

    Directory of Open Access Journals (Sweden)

    Matthijn C Hesselman

    Full Text Available Novel microbial cultivation platforms are of increasing interest to researchers in academia and industry. The development of materials with specialized chemical and geometric properties has opened up new possibilities in the study of previously unculturable microorganisms and has facilitated the design of elegant, high-throughput experimental set-ups. Within the context of the international Genetically Engineered Machine (iGEM competition, we set out to design, manufacture, and implement a flow device that can accommodate multiple growth platforms, that is, a silicon nitride based microsieve and a porous aluminium oxide based microdish. It provides control over (co-culturing conditions similar to a chemostat, while allowing organisms to be observed microscopically. The device was designed to be affordable, reusable, and above all, versatile. To test its functionality and general utility, we performed multiple experiments with Escherichia coli cells harboring synthetic gene circuits and were able to quantitatively study emerging expression dynamics in real-time via fluorescence microscopy. Furthermore, we demonstrated that the device provides a unique environment for the cultivation of nematodes, suggesting that the device could also prove useful in microscopy studies of multicellular microorganisms.

  17. African Plate Seismicity and Gravity Field Anomalies

    Science.gov (United States)

    Ryzhii, B. P.; Nachapkin, N. I.; Milanovsky, Svet

    The analysis of connection plate of earthquakes of the African continent with Bouguer gravity anomalies is carried out. As input dataSs were used the catalog of earthquakes and numeral map of Bouguer gravity field. The catalog contains geographical coor- dinates of epicenters and magnitudes of 8027 earthquakes recorded on continent and adjacent oceanic areas for the period from 1904 to 1988 years. The values of a gravity field preset in knots of a grid with a step 1 grade. For the analysis of plate seismicity from the catalog the parameters of 6408 earthquakes were chosen, which one have taken place in the field of restricted shore line. The earthquakes fixed in a band of a concatenation of continent with the Arabian plate were excluded from the analysis. On the basis of a numeral gravity map for everyone epicenter the value of Bouguer anomaly was calculated. The allocation of epicenters of earthquakes with magnitude M is obtained depending on value of a gravity Bouguer field. The outcomes of a sta- tistical analysis testify that practically all earthquakes are associated with the areas with negative values of Bouguer gravity field. Thus in areas with values of a field -160 mgal to -100 mgal there was 80 % of all earthquakes. It is necessary to note, that the mean value of the field for the African continent is -70 mgal. Obtained result gives us the possibility to make a conclusion about connection of plate earthquakes of Africa predominantly with structural complexes of earth crust with lower density. These out- comes are in the consent with a hypothesis of one of the authors (Ryzhii B.P.) about connection of plate earthquakes hypocenters on the territory of Russia with negative values of a gravity field and heightened silica content in the Earth crust. This work was supported with RFFI grant N 00-05-65067

  18. Development of user interface and of the data base "Earth, Moon and Planets" in the VBA environment for teaching students in the Kazan state universities

    Science.gov (United States)

    Petrova, N.; Tatarinov, P.; Akutina, M.

    2009-04-01

    In the frame of bachelor and master's degree diploma work the students accumulate and do structure distribution of necessary information about the spin-orbital, dynamical and geophysical characteristics of a planet. The information about the every planet is written into Excel WorkBook, the spreadsheets of which are the data base. The names of sheets reflect their content: "General Data", "Dynamics", "Geophysics", "Engineering", "References", Slides" etc. These data are taken from the last scientific articles dedicated to the modern problems of the planetary investigations. Especial interest is connected to the Lunar sciences - last data about surface mineral distribution, crust thickness and gravity field, slides with photographies received by Video Camera and various instruments situated on the board of Lunar SELENE mission (Japan, 2007-2009 yrs). The work with the data base is executed, using elements of the object-oriented programming. The students study to include into the UserForms standard means of Windows - Dialog Windows, TextBox, CommandButton, ComboBox, ScrollBar etc., and to support these elements by the macros written in programming language VBA. The main attention in the software support of the data base is done onto opportunity to investigate the two-three layer structure of a planet via modeling of its free nutation periods - Chandler-like Wobbles, Free Core Nutation, Inner Core Wobbles and Free Inner Core Nitation and their engineering estimation for space mission observations. The results are presented in the form of tables in Sheets and of diagrams constructed by special buttons of the UserForms on the basis of the calculated tables. The research was supported by the Russian-Japanese grant RFFI-JSPS N 07-02-91212, (2007 - 2009).

  19. Investigation of the middle atmosphere of Venus as a key to understand its dynamics

    Science.gov (United States)

    Zasova, L. V.; Khatountsev, I. V.; Ignatiev, N. I.; Moroz, V. I.; Formisano, V.; Bellucci, G.

    2001-11-01

    Middle atmosphere of Venus (50 - 100km) is a very important part of the atmosphere. More than 70 % of the absorbed solar energy deposits there, providing an important source of energy to support thermal structure and dynamics. We investigate the thermal tides distribution, which is possibly responsible for the support of the superrotation. Temperature and aerosol vertical profiles were retrieved in a self consistent way from Venera-15 IR spectrometry data with vertical resolution of several kilometers. The temperature variation at the isobaric levels vs. solar longitude was presented as a superposition of the cosines with periods of 1, 1/2, 1/3 and 1/4 Venusian days with amplitude and phase depending on latitude and altitude. In particular, in the upper clouds, where most of the solar energy absorbs, all four tidal components have significant amplitudes. For the midlatitude jet the solar related periods were also found with maximal amplitude of 1/2 days period. It was also discovered that the jet changes its position in such a way that the laws of the conservation of momentum and flux are satisfied. The Fourier spectrometer on Venera-15 may be considered as a precursor of the instrument of this kind for the future missions. A functioning of the Planetary Fourier Spectrometer, with spectral range 1-50 mkm, proposed for Venus Express mission together with UV (0.2-0.5 mm) mapping spectrometer, will be enable to get answers to the fundamental questions of the middle atmosphere: clouds formation, nature of the ``unknown" UV-absorber and the mechanism of support of the superrotation. This work was supported by the grant RFFI - 02-01-17841.

  20. Synthetic biology and biosecurity: challenging the "myths".

    Science.gov (United States)

    Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

    2014-01-01

    Synthetic biology, a field that aims to "make biology easier to engineer," is routinely described as leading to an increase in the "dual-use" threat, i.e., the potential for the same scientific research to be "used" for peaceful purposes or "misused" for warfare or terrorism. Fears have been expressed that the "de-skilling" of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five "myths" that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these "myths" play an important role in defining synthetic biology as a "promissory" field of research and as an "emerging technology" in need of governance.

  1. Synthetic biology and biosecurity: challenging the ‘myths’

    Directory of Open Access Journals (Sweden)

    Catherine eJefferson

    2014-08-01

    Full Text Available Synthetic biology, a field that aims to ‘make biology easier to engineer’, is routinely described as leading to an increase in the ‘dual use’ threat, i.e. the potential for the same piece of scientific research to be ‘used’ for peaceful purposes or ‘misused’ for warfare or terrorism. Fears have been expressed that the ‘de-skilling’ of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of DIY biology communities and of the student iGEM competition has come to epitomize this supposed trend towards greater ease of access and the associated potential threat from rogue actors. In this article, we identify 5 ‘myths’ that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these ‘myths’ play an important role in defining synthetic biology as a ‘promissory’ field of research and as an ‘emerging technology’ in need of governance.

  2. Synthetic Biology and Biosecurity: Challenging the “Myths”

    Science.gov (United States)

    Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

    2014-01-01

    Synthetic biology, a field that aims to “make biology easier to engineer,” is routinely described as leading to an increase in the “dual-use” threat, i.e., the potential for the same scientific research to be “used” for peaceful purposes or “misused” for warfare or terrorism. Fears have been expressed that the “de-skilling” of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five “myths” that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these “myths” play an important role in defining synthetic biology as a “promissory” field of research and as an “emerging technology” in need of governance. PMID:25191649

  3. Do lower vertebrates suffer from motion sickness?

    Science.gov (United States)

    Lychakov, Dmitri

    , there is absent the hypothetical center of subjective «nauseating» sensations; therefore, they are immune to the motion sickness. This work was partly supported by Russian grant RFFI 14-04-00601.

  4. Pioneering a Biobased UAS

    Science.gov (United States)

    Block, Eli; Byemerwa, Jovita; Dispenza, Ross; Doughty, Benjamin; Gillyard, KaNesha; Godbole, Poorwa; Gonzales-Wright, Jeanette; Hull, Ian; Kannappan, Jotthe; Levine, Alexander; hide

    2015-01-01

    With the exponential growth of interest in unmanned aerial vehicles (UAVs) and their vast array of applications in both space exploration and terrestrial uses such as the delivery of medicine and monitoring the environment, the 2014 Stanford-Brown-Spelman iGEM team is pioneering the development of a fully biological UAV for scientific and humanitarian missions. The prospect of a biologically-produced UAV presents numerous advantages over the current manufacturing paradigm. First, a foundational architecture built by cells allows for construction or repair in locations where it would be difficult to bring traditional tools of production. Second, a major limitation of current research with UAVs is the size and high power consumption of analytical instruments, which require bulky electrical components and large fuselages to support their weight. By moving these functions into cells with biosensing capabilities – for example, a series of cells engineered to report GFP, green fluorescent protein, when conditions exceed a certain threshold concentration of a compound of interest, enabling their detection post-flight – these problems of scale can be avoided. To this end, we are working to engineer cells to synthesize cellulose acetate as a novel bioplastic, characterize biological methods of waterproofing the material, and program this material’s systemic biodegradation. In addition, we aim to use an “amberless” system to prevent horizontal gene transfer from live cells on the material to microorganisms in the flight environment. So far, we have: successfully transformed Gluconacetobacter hansenii, a cellulose-producing bacterium, with a series of promoters to test transformation efficiency before adding the acetylation genes; isolated protein bands present in the wasp nest material; transformed the cellulose-degrading genes into Escherichia coli; and we have confirmed that the amberless construct prevents protein expression in wild-type cells. In addition, as

  5. Zur Durchführbarkeit eines regelmäßigen Trainings mit der Nintendo Wii Fit Plus bei Frauen nach der Schwangerschaft

    Directory of Open Access Journals (Sweden)

    Nitzsche N

    2011-01-01

    Full Text Available Sport im Sinne eines regelmäßigen körperlichen Trainings sollte aus gesundheitlichen Gründen nach einer Schwangerschaft empfohlen werden. Jedoch müssen an diese Aktivitäten besondere Ansprüche gestellt werden. Die Beanspruchung sollte moderat und mit geringem Risiko sein. Weiters muss die körperliche Aktivität in den Tagesablauf einer jungen Mutter integrierbar sein. Hierzu könnten digitale Spiele mit Ganzkörperaktivitäten sinnvoll eingesetzt werden. Ziel dieser Trainingsstudie war es, möglichen Einsatz und mögliche Wirkung ausgewählter Übungen der Nintendo Wii Fit Plus bei postnatalen Frauen zu überprüfen. Dabei wurden subjektive Eindrücke wie das Spielerleben und wahrgenommene Beanspruchung erhoben. Die Wirkung auf die aerobe Ausdauerleistungsfähigkeit wurde durch eine 6-wöchige Intervention überprüft. An der Studie nahmen 8 Probandinnen (Alter 29,0 ± 4,6 Jahre, Größe 1,7 ± 0,1 m, Body-Mass-Index [BMI] 25,1 ± 3,1 kg/m², postnatal 6,3 ± 1,9 Wochen teil. Ergebnisse: Die Probandinnen zeigten nach einmaligem Spielen eine hohe bis sehr hohe Motivation, dieses Spiel noch mal zu spielen. Es wurde als nicht stressig mit mittlerer Spielgeschwindigkeit bei einfacher und übersichtlicher Bedienung bewertet. Über den Beobachtungszeitraum nahmen die Frauen eine moderate (etwas anstrengende Beanspruchung mit hohem Spaßempfinden wahr. Signifikante Gewichtsreduktionen sowie eine Verbesserung der aeroben Leistungsfähigkeit konnten nicht festgestellt werden. Schlussfolgernd bleibt festzuhalten, dass trotz nicht-signifikanter metabolischer und morphologischer Adaptionen eine hohe Motivation zu erwarten ist, was unter gegebenen Übungsvariationen der Nindento Wii Fit Plus zu regelmäßigem Training führen kann. Da diese Studie nur Pilotcharakter hatte, wäre unter randomisierten kontrollierten Bedingungen eine Untersuchung mit größerem Probandenumfang durchzuführen.

  6. Zur Durchführbarkeit eines regelmäßigen Trainings mit der Nintendo Wii Fit Plus bei Frauen in der Schwangerschaft

    Directory of Open Access Journals (Sweden)

    Nitzsche N

    2010-01-01

    Full Text Available Sport im Sinne eines regelmäßigen körperlichen Trainings sollte aus gesundheitlichen Gründen nach einer Schwangerschaft empfohlen werden. Jedoch müssen an diese Aktivitäten besondere Ansprüche gestellt werden. Die Beanspruchung sollte moderat und mit geringem Risiko sein. Weiters muss die körperliche Aktivität in den Tagesablauf einer jungen Mutter integrierbar sein. Hierzu könnten digitale Spiele mit Ganzkörperaktivitäten sinnvoll eingesetzt werden. Ziel dieser Trainingsstudie war es, möglichen Einsatz und mögliche Wirkung ausgewählter Übungen der Nintendo Wii Fit Plus bei postnatalen Frauen zu überprüfen. Dabei wurden subjektive Eindrücke wie das Spielerleben und wahrgenommene Beanspruchung erhoben. Die Wirkung auf die aerobe Ausdauerleistungsfähigkeit wurde durch eine 6-wöchige Intervention überprüft. An der Studie nahmen 8 Probandinnen (Alter 29,0 ± 4,6 Jahre, Größe 1,7 ± 0,1 m, Body-Mass-Index [BMI] 25,1 ± 3,1 kg/m², postnatal 6,3 ± 1,9 Wochen teil. Ergebnisse: Die Probandinnen zeigten nach einmaligem Spielen eine hohe bis sehr hohe Motivation, dieses Spiel noch mal zu spielen. Es wurde als nicht stressig mit mittlerer Spielgeschwindigkeit bei einfacher und übersichtlicher Bedienung bewertet. Über den Beobachtungszeitraum nahmen die Frauen eine moderate (etwas anstrengende Beanspruchung mit hohem Spaßempfinden wahr. Signifikante Gewichtsreduktionen sowie eine Verbesserung der aeroben Leistungsfähigkeit konnten nicht festgestellt werden. Schlussfolgernd bleibt festzuhalten, dass trotz nicht-signifikanter metabolischer und morphologischer Adaptionen eine hohe Motivation zu erwarten ist, was unter gegebenen Übungsvariationen der Nintendo Wii Fit Plus zu regelmäßigem Training führen kann. Da diese Studie nur Pilotcharakter hatte, wäre unter randomisierten kontrollierten Bedingungen eine Untersuchung mit größerem Probandenumfang durchzuführen.

  7. Life in the Clouds of Venus? An Experimental Synthetic Biology Approach

    Science.gov (United States)

    Rothschild, L. J.; Paulino-Lima, I. G.; Amatya, D.; Bajar, B.; Geilich, B.; Hu, J.; Jackson, C. J.

    2015-01-01

    replication and is cell-cycle dependent [4]. These promoters were fused to a GFP reporter, transformed into E. coli. The constructs were deposited in the iGEM registry as K847210: Escherichia coli DNA-replication dependent polA promoter K847211: Escherichia coli cell-division dependent nrd promoter Results: Our constructs displayed fluorescence when transformed into NEB-5alpha competent cells. While nrdP-E0840 displayed sufficient fluorescence as verified by fluorescent microscopy, the original polAP-E0840 construct (which uses mut3b GFP) exhibited low expression; while fluorescence was visible under the microscope, the signal was too weak for the camera to recognize. The polA promoter was therefore digest-ed with EcoRI and SpeI then ligated into plasmid pNCS containing a RBS, Clover, and a terminator. Clover is a highly engineered green fluorescent protein that exhibits extreme brightness [5] Fluoresence time course data demonsrated that the genes were induced in a cell cycle dependant manner [6]. Our assays via microscopy and the bulk assay shows that our promoters are functional as cell cycle reporters.Conclusions: The application of such tools are widespread and not limited to astrobiology; nrdP could be used to determine doubling times empirically and could possibly extrapolate DNA content from intensity of signals expressed by polAP. However, we are pri-marily interested in its use in astrobiology.

  8. Computer simulating observations of the Lunar physical libration for the Japanese Lunar project ILOM

    Science.gov (United States)

    Petrova, Natalia; Hanada, Hideo

    2010-05-01

    are calculated using the analytical theory of physical libration Petrova et al. (2008; 2009). We cannot use Newton's method for solution of the equation, because the Jacobian | | || δδfx11 δδfx12 δδf1x3-|| || δδfx2 δδfx2 δδf2x-|| J(X ) = || δf13 δf23 δ3f3-|| = 0. || δx1 δx2 δx3 || We transformed equations to the iteration form xi = φi(X). Used iteration methods have unsatisfactory convergence: inaccuracy in polar distance of 1 milliseconds of arc causes inaccuracy of 0.01arcsec in ρ and in Iσ, and 0.1 arcsec in ?. Results of our computer simulating showed It's necessary to carry out measuring of polar distances of stars in several meridians simultaneously to increase sample of stars. It's necessary to find additional links (relations) between observed parameters and libration angles to have stable mathematical methods to receive solutions for lunar rotation with high accuracy. The research was supported by the Russian-Japanese grant RFFI-JSPS 09-02-92113, (2009-2010) References: Hanada H., Noda H., Kikuchi F. et al., 2009. Different kind of observations of lunar rotation and gravity for SELENE-2. Proc of conf. Astrokazan-2009, August 19 - 26, Kazan, Russia. p. 172-175 Petrova N., Gusev A., Kawano N., Hanada H., 2008. Free librations of the two-layer Moon and the possibilities of their detection. Advances in Space Res., v 42, p. 1398-1404 Petrova N., Gusev A., Hanada H., Ivanova T., Akutina V., 2009. Application of the analytical theory of Lunar physical libration for simulating observations of stars for the future Japanese project ILOM. Proc of conf. Astrokazan-2009, August 19 - 26, Kazan, Russia. p.197 - 201.

  9. Climate and N-Mineral Fertilization Changes on Triticale (XTriticosecale W.) Yield

    Science.gov (United States)

    László, Márton, ,, Dr.

    2010-05-01

    -600 mm growth period rainfall. References Harnos, Zs. 1993. Időjárás és időjárás-termés összefüggéseinek idősoros elemzése. In: Aszály 1983 (Szerk.: Baráth, Cs-né., Győrffy, B., és Harnos, Zs.). KÉE. Budapest Johnston, A. E. 2000. Some aspects of nitrogen use efficiency in arable agriculture. K. Scogs-o. Lantbr. Akad. Tidskr. 139: 8. José, A. B., Estáquio, M. J., and Márton, L. 2001. Results of Crotalaria ssp. effects on soil conservation. In: Congress on Conservation Agriculture, (Eds Armando, M. V.), ECAF., Madrid, 5, pp 1-4. Márton, L. 2001a. Climate change and N, P, K, Mg fertilization effect analysis at Tisza-river basin in a long term field experiment. Szent István University, Gödöllő, p. 9. Márton, L. 2001b. Climate change, N-fertilisation effect on rye (Secale cereale L.) yield in a long term field experiment. In: Rural development-Ecologically farming-Agriculture, (Eds Palkovics, M.), University Veszprém, Keszthely, pp 924-929. Márton, L. 2002a. Climate-Rainfall Change (CRC) and mineral fertilisation (MF) effects on different crop production. In: Challenges of the new millennium our joint responsibility. (Eds A. Borhidi). MTA ÖBKI. Budapest. 1, pp 110-111. Márton, L. 2002b. Relationships between rainfall, nutrient supplies and the yield of winter wheat (Triticum aestivum L.). Plant Production 51: 529-542. Márton, L. 2003. Relationships between rainfall, nutrient supplies and the yield of triticale. Plant Production. In press Márton, L., and Pekli, J. 2003. Plant production under sub-arctical and temperate climate conditions. SZIU. Gödöllő Acknowledgement This research was supported by Hungarian Academy of Sciences, H-Budapest Adderss of the author Dr. Márton László Ph.D Research Institute for Soil Science and Agricultural Chemistry of the Hungarian Academy of Sciences, 1022 H-Budapest, Herman O. u. 15. E-mail:marton@rissac.hu

  10. Environmental Change: Precipitation and N, P, K, mg Fertilization Influences on Crop Yield Under Temperate Climate Conditions

    Science.gov (United States)

    László Phd, Dd. M.

    2009-04-01

    (Eds Armando MV), ECAF., Madrid, 2001. 5, 1-4. [5] Kádár I., Márton L. and Horváth S.: Mineral fertilisation of potato (Solanum tuberosum L.) on calcareous chernozem soil. Plant Production, 2000, 49, 291-306. [6] Harnos, Zs.: Időjárás és időjárás-termés összefüggéseinek idősoros elemzése, [in:] Aszály 1983 (Szerk.: Baráth Cs-né, Győrffy B., Harnos Zs.). KÉE. Budapest 1993. [7] Márton L.: Climate-Rainfall Change (CRC) and mineral fertilisation (MF) effects on different crop production. [in:] Challenges of the new millennium our joint responsibility. (Eds A. Borhidi). MTA ÖBKI, Budapest 2002, 1, 110-111. [8] Márton L.: Rainfall, mineral fertilisation and winter wheat (Triticum aestivum L.) yield relations. Plant Production, 2002, 51, 529-542.

  11. Liming and Fertilization Effects on Triticale (XTriticosecale W.) Yield Between 1999 and 2006

    Science.gov (United States)

    László Phd, M., ,, Dr.

    2009-04-01

    Hungarian Academy of Sciences, H-Budapest and the Hungarian and Spanish Intergovernmental S & T Cooperation Project of E-2/04-OMFB-00112/2005 and Hungarian and Indian Intergovernmental S & T Cooperation Project of IND-3/03/2006. References Adams, R. M., Fleming, R. A., Chang, C. C., McCarl, B. A. and Rosenzweig, C. 1995. A reassessment of the economic effects of global climate change on U.S. agriculture. Climatic Change, Vol. 30, pp. 147-167. Asbjorn, T., Michelle, T. and Bárd, R. 2004. Climate Change Impacts on Agricultural Productivity in Norway. CICERO. Oslo Cynthia, R. & Ana, I. 2006. Potential impact of climate change on world food supply. Data sets from a major crop modeling study. Socioeconomic Data and Applications Center. Columbia University. New York Eric La F. 2006. Adapting crops for climate change. UBC Botanical Garden and Centre for Plant Researches. EU (European Union). 2003. Drought costs EU farmers euro of 11 billion. European Report, Brussels Harnos, Zs. 1993. Weather and weather-yield interaction analysis. (In Hungarian) In: Aszály 1983 (Szerk.: Baráth Cs-né., Győrffy B., Harnos Zs.). KÉE. Budapest Johnston, A. E. 2000. Some aspects of nitrogen use efficiency in arable agriculture. K. Scogs-o. Lantbr. Akad. Tidskr. 139:8. Jolánkai M. 2005. Effect of climate change on plant cultivation. (In Hungarian) In: „AGRO-21" Füzetek. 41. 47-58. Kádár I. - Németh T. - Szemes I. (1999): Triticale trágyareakciója a nyírlugosi tartamkísérletben. Növénytermelés. 48:647-661. Kádár I. - Szemes I. (1994): A nyírlugosi tartamkísérlet 30 éve. MTA Talajtani és Agrokémiai Kutató Intézete. Budapest. Láng I. (1973): Műtrágyázási tartamkísérletek homoktalajokon. Akad. Doktori Disszertáció. Kézirat. MTA. Budapest. Láng I., 2005. Weather and climate change: change-effect-response. (In Hungarian) In: „AGRO-21" Füzetek. 43. 3-10. Márton L. (2002): A csapadék és tápanyagellátottság hatásának vizsgálata a tritikale term

  12. Climate Change: Natural Water and Fertilization Effects on Winter Rye (Secale cereale L.) Yield in Monoculture

    Science.gov (United States)

    László Phd, M., ,, Dr.

    2009-04-01

    biculture on acidic sandy soil (Nyírlugos) under the similar fertilization and rainfall conditions. These results show rye production is totally (66.9%) dependent on rainfall and fertilization changes. Acknowledgement: We are grateful to Hungarian Academy of Sciences who supplied experiment, data and Internet URLs, as well as helping on other ways with this paper. Most of all, I would like to thank National Office for Research and Technology, Hungary and Hungarian Science and Technology Foundation, Hungary (Project No.: OMFB-00112/2005-E-2/04) for their support during the course of this research and my presentation. References Barrow, E. M., Hulme, M., Semenov, M. A. & Brooks, R. J., 2000. Climate change scenarios. In: Climate Change, Climatic Variability and Agriculture in Europe (ed's.: Downing, T. E., Harrison, P. A., Butterfield, R. E. and Londsdale, K. G.). European Commision, Brussel Easterling, D. R., Evans, J. L., Groisman, YA. P., Karl, T. R., Kunkel, K. E. & Ambenje, P., 1999. Observed variability and trends in extreme climate events. A brief review. Bulletin of the American Meteorological Society, 81:417-425. EM., 2004. International Disaster Database. Washington EU., 2003. Drought costs EU farmers euro of 11 billion. European Report, Brussels Harnos, Zs., 1993. Időjárás és időjárás-termés összefüggéseinek idősoros elemzése. Weather and weather-yield interaction analysis In: Aszály 1983 (Szerk.: Baráth Cs-né., Győrffy B., Harnos Zs.). KÉE. Budapest Harnos, Zs., 2005. A klímaváltozás és lehetséges hatásai a világ mezőgazdaságára. Magyar Tudomány. 7. 826-832. Hulme, M., Jenkins, G., J. LU., X. Turnpenny., J. R. Mitchell., T. D. Jones., R. G. Lowe., J. Murphy., J. M. Hassell., D. Boorman., P. Mcdonald R. & Hill, S., 2002. Climate change scenarios for the 21st century for the UK (UKCIP02-Technical Report). University of Oxford. Oxford Johnston, A. E., 2000. Some aspects of nitrogen use efficiency in arable agriculture. K. Scogs-o. Lantbr