Characterization of Size, Composition and Origins of Dust in Fusion Devices. Summary Report of the Second Research Coordination Meeting

International Nuclear Information System (INIS)

Braams, B.J.; Skinner, C.H.

2010-11-01

Eleven experts on processes of dust in fusion experiments met for the 2nd Research Coordination Meeting (RCM) of the Coordinated Research Project (CRP) on 'Characterization of size, composition and origins of dust in fusion devices' held at IAEA Headquarters 21-23 June 2010. Participants summarized their studies on dust in fusion experiments and reviewed progress made since the first RCM. Gaps in knowledge were identified and a plan of work for the remainder of the CRP was developed. Presentations, discussions and recommendations of the RCM are summarized in this report. Eleven experts on processes of dust in fusion experiments met for the 2nd Research Coordination Meeting (RCM) of the Coordinated Research Project (CRP) on 'Characterization of size, composition and origins of dust in fusion devices' held at IAEA Headquarters 21-23 June 2010. Participants summarized their studies on dust in fusion experiments and reviewed progress made since the first RCM. Gaps in knowledge were identified and a plan of work for the remainder of the CRP was developed. Presentations, discussions and recommendations of the RCM are summarized in this report. (author)

Water resources management in Tanzania: identifying research ...

African Journals Online (AJOL)

This paper aims at identifying research gaps and needs and recommendations for a research agenda on water resources management in Tanzania. We reviewed published literature on water resources management in Tanzania in order to highlight what is currently known, and to identify knowledge gaps, and suggest ...

What does originality in research mean? A student's perspective.

Science.gov (United States)

Edwards, Mandy

2014-07-01

To provide a student's perspective of what it means to be original when undertaking a PhD. A review of the literature related to the concept of originality in doctoral research highlights the subjective nature of the concept in academia. Although there is much literature that explores the issues concerning examiners' views of originality, there is little on students' perspectives. A snowballing technique was used, where a recent article was read, and the references cited were then explored. Given the time constraints, the author recognises that the literature review was not as extensive as a systematic literature review. It is important for students to be clear about what is required to achieve a PhD. However, the vagaries associated with the formal assessment of the doctoral thesis and subsequent performance at viva can cause considerable uncertainty and anxiety for students. Originality in the PhD is a subjective concept and is not the only consideration for examiners. Of comparable importance is the assessment of the student's ability to demonstrate independence of thought and increasing maturity so they can become independent researchers. This article expresses a different perspective on what is meant when undertaking a PhD in terms of originality in the doctoral thesis. It is intended to help guide and reassure current and potential PhD students.

Original Research Original Research

African Journals Online (AJOL)

RAGHAVENDRA

research is to determine the level of interference ... perceived in the foreign language production (Aber. 2013). ... Accordingly, it is important to help learners reduce th ... Official International Journal of Wollega University, Ethiopia .... e learning process, learners .... them to self-evaluate errors and improve their English writing ...

Original Research Original Research

African Journals Online (AJOL)

User

This research pape of mobile advertising in the mind of customers espec. Delhi, India. Further it also tries to find out the go product / services due to mobile advertising. INTRODUCTION. Mobile advertising is a brand new phenomenon. Yunos et al. (2003) defined mobile advertising as marketing and advertising activities.

Original Research

African Journals Online (AJOL)

A facility based comparative cross-sectional study ... Health care delivery should consider the desire for children by men and .... Socio-Demographic Characteristics of the .... For substitution, children are an important part of marriage, current child needs sibling, original desires .... does not, the only way to avoid the risk of.

Original Research Original Research

African Journals Online (AJOL)

User

2013-06-19

Jun 19, 2013 ... After collecting knowledge, attitude and behavior inventory questionnaire, the researcher conducted. FGDs that contain 1 male and 1 female student from grade 9, 10, 11 and 12 for 2 hours in two sessions (1 hour for each session) which are selected with the support of room teachers. Due to limited time to ...

Peer Mentoring to Facilitate Original Scientific Research by Students With Special Needs

Science.gov (United States)

Danch, J. M.

2007-12-01

Developed to allow high school students with special needs to participate in original scientific research, the Peer Mentoring Program was a supplement to existing science instruction for students in a self-contained classroom. Peer mentors were high school seniors at the end of a three-year advanced science research course who used their experience to create and develop inquiry-based research activities appropriate for students in the self- contained classroom. Peer mentors then assisted cooperative learning groups of special education students to facilitate the implementation of the research activities. Students with special needs successfully carried out an original research project and developed critical thinking and laboratory skills. Prior to embarking on their undergraduate course of study in the sciences, peer mentors developed an appreciation for the need to bring original scientific research to students of all levels. The program will be expanded and continued during the 2007-2008 school year.

Original Research Clinical characteristics and outcomes of patients ...

African Journals Online (AJOL)

Epidemiological data on stroke in Zimbabwe are scarce and few clinical studies have been performed to date. ... Original Research ... of the patients were in the economically active group with ..... in Sub-Saharan Africa: what we know now; International Journal of ... University of Medicine and Dentistry OF New Jersey.

Original Research Article Prevalence of Neonatal Jaundice on

African Journals Online (AJOL)

HP

The journal welcomes original research papers, reviews and case reports on current topics of special interest and relevance. All manuscripts will be .... also been reported to be the commonest cause of neonatal admission to the Children's ... as a result of the neurologic effect of neonatal jaundice. Methods. This study was ...

Quantitative phase-digital holographic microscopy: a new imaging modality to identify original cellular biomarkers of diseases

KAUST Repository

Marquet, P.; Rothenfusser, K.; Rappaz, B.; Depeursinge, Christian; Jourdain, P.; Magistretti, Pierre J.

2016-01-01

parallelization and automation processes, represents an appealing imaging modality to both identify original cellular biomarkers of diseases as well to explore the underlying pathophysiological processes.

Using molecular tools to identify the geographical origin of a case of human brucellosis.

Science.gov (United States)

Muchowski, J K; Koylass, M S; Dainty, A C; Stack, J A; Perrett, L; Whatmore, A M; Perrier, C; Chircop, S; Demicoli, N; Gatt, A B; Caruana, P A; Gopaul, K K

2015-10-01

Although Malta is historically linked with the zoonosis brucellosis, there had not been a case of the disease in either the human or livestock population for several years. However, in July 2013 a case of human brucellosis was identified on the island. To determine whether this recent case originated in Malta, four isolates from this case were subjected to molecular analysis. Molecular profiles generated using multilocus sequence analysis and multilocus variable number tandem repeat for the recent human case isolates and 11 Brucella melitensis strains of known Maltese origin were compared with others held on in-house and global databases. While the 11 isolates of Maltese origin formed a distinct cluster, the recent human isolation was not associated with these strains but instead clustered with isolates originating from the Horn of Africa. These data was congruent with epidemiological trace-back showed that the individual had travelled to Malta from Eritrea. This work highlights the potential of using molecular typing data to aid in epidemiological trace-back of Brucella isolations and assist in monitoring of the effectiveness of brucellosis control schemes.

Identifying Galactic Cosmic Ray Origins With Super-TIGER

Science.gov (United States)

deNolfo, Georgia; Binns, W. R.; Israel, M. H.; Christian, E. R.; Mitchell, J. W.; Hams, T.; Link, J. T.; Sasaki, M.; Labrador, A. W.; Mewaldt, R. A.;

[Herbal textual research on origins of Chonglou].

Science.gov (United States)

Jiang, Lu; Kang, Li-Ping; Liu, Da-Hui; Peng, Hua-Sheng; Xie, Jin; Chen, Min

2017-09-01

Based on the field investigation, this paper researched the germplasms and geoherbs habitat of Chonglou in ancient herbal books systematically. The results showed that, Chonglou in ancient herbal books sometimes referred to certain specific germplasm, while sometimes it referred to many species derived from genus Paris except Sect. Paris. The medicinal material Chonglou in Chinese Materia Medica Bencaotujing and Bencaomengquan was verified as P. polyphylla var. chinensis, which could be P. polyphylla in Xinxiubencao, and it should include P. polyphylla or P. polyphylla var. stenophylla in Bencaogangmu. However, it proved to be a variety of species from Paris that can used as Chonglou in Diannanbencao and Zhiwumingshitukao. Moreover, the origins of Chonglou were correspondingly more diverse, with its producing areas changed from North to South. Therefore, with the resources increasing endangered, the botanical origin of Chonglou should be further studied. Copyright© by the Chinese Pharmaceutical Association.

Original Research Factors associated with hospital arrival time after ...

African Journals Online (AJOL)

Original Research. Factors associated with hospital arrival time after the onset of stroke symptoms: A cross-sectional study at two teaching hospitals in Harare, Zimbabwe .... hypertension causing small vessel disease which outweigh the causes of ..... Stroke Mechanism in Atherosclerotic Middle Cerebral Artery Disease:.

Original Researc Original Research

African Journals Online (AJOL)

RAGHAVENDRA

Abstract. The aim of the present research is to develop the f effect of ... Science, Technology and Arts Research J. Sci. Technol. ..... “Science, Technology and Innovation for National ... Latin American Journal of Pharmacy 3: 1135-1141. Vemula ...

Study of a methodology of identifying important research problems by the PIRT process

International Nuclear Information System (INIS)

Aoki, Takayuki; Takagi, Toshiyuki; Urayama, Ryoichi; Komura, Ichiro; Furukawa, Takashi; Yusa, Noritaka

2013-01-01

In this paper, we propose a new methodology of identifying important research problems to be solved to improve the performance of some specific scientific technologies by the phenomena identification and ranking table (PIRT) process, which has been used as a methodology for demonstrating the validity of the best estimate simulation codes in USNRC licensing of nuclear power plants. It keeps the fundamental concepts of the original PIRT process but makes it possible to identify important factors affecting the performance of the technologies from the viewpoint of the figure of merit and problems associated with them, which need to be solved to improve the performance. Also in this paper, we demonstrate the effectiveness of the developed method by showing a specific example of the application to physical events or phenomena in objects having fatigue or SCC crack(s) under ultrasonic testing and eddy current testing. (author)

Measuring originality: common patterns of invention in research and technology organizations

Energy Technology Data Exchange (ETDEWEB)

Tang, D.L.; Wiseman, E.; Keating, T.; Archambeault, J.

2016-07-01

The National Research Council of Canada (NRC) co-chairs an international working group on performance benchmarking and impact assessment of Research and Technology Organizations (RTO). The Knowledge Management branch of the NRC conducted the patent analysis portion of the benchmarking study. In this paper, we present a Weighted Originality index that can more accurately measure the spread of technological combinations in terms of hierarchical patent classifications. Using this patent indicator, we revealed a common pattern of distribution of invention originality in RTOs. Our work contributes to the methodological advancement of patent measures for the scientometric community. (Author)

A spectroscopic tool for identifying sources of origin for materials of military interest

Science.gov (United States)

Miziolek, Andrzej W.; De Lucia, Frank C.

2014-05-01

There is a need to identify the source of origin for many items of military interest, including ammunition and weapons that may be circulated and traded in illicit markets. Both fieldable systems (man-portable or handheld) as well as benchtop systems in field and home base laboratories are desired for screening and attribution purposes. Laser Induced Breakdown Spectroscopy (LIBS) continues to show significant capability as a promising new tool for materials identification, matching, and provenance. With the use of the broadband, high resolution spectrometer systems, the LIBS devices can not only determine the elemental inventory of the sample, but they are also capable of elemental fingerprinting to signify sources of origin of various materials. We present the results of an initial study to differentiate and match spent cartridges from different manufacturers and countries. We have found that using Partial Least Squares Discriminant Analysis (PLS-DA) we are able to achieve on average 93.3% True Positives and 5.3% False Positives. These results add to the large body of publications that have demonstrated that LIBS is a particularly suitable tool for source of origin determinations.

What do medical students understand by research and research skills? Identifying research opportunities within undergraduate projects.

Science.gov (United States)

Murdoch-Eaton, Deborah; Drewery, Sarah; Elton, Sarah; Emmerson, Catherine; Marshall, Michelle; Smith, John A; Stark, Patsy; Whittle, Sue

2010-01-01

Undergraduate research exposure leads to increased recruitment into academic medicine, enhanced employability and improved postgraduate research productivity. Uptake of undergraduate research opportunities is reported to be disappointing, and little is known about how students perceive research. To investigate opportunities for undergraduate participation in research, recognition of such opportunities, and associated skills development. A mixed method approach, incorporating student focus and study groups, and documentary analysis at five UK medical schools. Undergraduates recognised the benefits of acquiring research skills, but identified practical difficulties and disadvantages of participating. Analysis of 905 projects in four main research skill areas - (1) research methods; (2) information gathering; (3) critical analysis and review; (4) data processing - indicated 52% of projects provided opportunities for students to develop one or more skills, only 13% offered development in all areas. In 17%, project descriptions provided insufficient information to determine opportunities. Supplied with information from a representative sample of projects (n = 80), there was little consensus in identifying skills among students or between students and researchers. Consensus improved dramatically following guidance on how to identify skills. Undergraduates recognise the benefits of research experience but need a realistic understanding of the research process. Opportunities for research skill development may not be obvious. Undergraduates require training to recognise the skills required for research and enhanced transparency in potential project outcomes.

Presentation of Original Research at the European Congress of Radiology 2010: Frequency of Publication in Medline-Indexed Journals Within 5 Years After Presentation.

Science.gov (United States)

Dollinger, Marco; Zeman, Florian; Müller-Wille, René; Beyer, Lukas Philipp; Stroszczynski, Christian; Bley, Thorsten Alexander; Wiggermann, Philipp

2018-04-01

 To determine the rate at which original studies presented orally at the European Congress of Radiology (ECR) 2010 were published in Medline-indexed journals and to identify factors predictive of publication.  A total of 869 abstracts were included in the study. A Medline search of articles published between March 2010 and February 2015 was conducted to identify articles written by the first, second, and/or last authors of all abstracts published in the Scientific Program of ECR 2010. The publication year, journal, country of origin, subspecialty and nature of the research (i. e., human, animal or technical) were recorded.  Between March 2010 and February 2015 a total of 450 abstracts (publication rate, 51.8 %) were subsequently published in 125 Medline-indexed journals, chiefly in European Radiology (11.1 %). 443/450 (98.4 %) articles were published in English language. The subspecialties of molecular imaging and cardiac imaging had the highest publication rates (75.0 % and 62.0 %, respectively), while computer application studies had the lowest (27.6 %). The nature of research, origin of the abstract and subspecialty significantly influenced the subsequent publication rate.  More than half of the original studies presented orally at ECR 2010 were subsequently published in Medline-indexed journals. More articles were published in the journal European Radiology than in any other identified journal.   · ECR 2010 had a high subsequent publication rate. · Most subsequently published articles were published in radiology journals. · Nearly all articles were published in the English language. · Dollinger M, Zeman F, Müller-Wille R et al. Presentation of Original Research at the European Congress of Radiology 2010: Frequency of Publication in Medline-Indexed Journals Within 5 Years After Presentation. Fortschr Röntgenstr 2017; 190: 327 - 333. © Georg Thieme Verlag KG Stuttgart · New York.

Identifying sites of replication initiation in yeast chromosomes: looking for origins in all the right places.

Science.gov (United States)

van Brabant, A J; Hunt, S Y; Fangman, W L; Brewer, B J

1998-06-01

DNA fragments that contain an active origin of replication generate bubble-shaped replication intermediates with diverging forks. We describe two methods that use two-dimensional (2-D) agarose gel electrophoresis along with DNA sequence information to identify replication origins in natural and artificial Saccharomyces cerevisiae chromosomes. The first method uses 2-D gels of overlapping DNA fragments to locate an active chromosomal replication origin within a region known to confer autonomous replication on a plasmid. A variant form of 2-D gels can be used to determine the direction of fork movement, and the second method uses this technique to find restriction fragments that are replicated by diverging forks, indicating that a bidirectional replication origin is located between the two fragments. Either of these two methods can be applied to the analysis of any genomic region for which there is DNA sequence information or an adequate restriction map.

Original Researc Original Research

African Journals Online (AJOL)

RAGHAVENDRA

communication skills were identified as peer mediat respectively. ... allows students to work together in small peer whereby .... and achievement in academic performance are worth ..... cognitive development influence each other, in such a.

Conscientiousness: Origins in Childhood?

Science.gov (United States)

Eisenberg, Nancy; Duckworth, Angela L.; Spinrad, Tracy L.; Valiente, Carlos

2014-01-01

In this review, we evaluate developmental and personality research with the aim of determining whether the personality trait of conscientiousness can be identified in children and adolescents. After concluding that conscientiousness does emerge in childhood, we discuss the developmental origins of conscientiousness with a specific focus on…

Experience of shipping Russian-origin research reactor spent fuel to the Russian Federation

International Nuclear Information System (INIS)

2009-11-01

The primary goal of the Russian Research Reactor Fuel Return (RRRFR) programme is to advance nuclear non-proliferation objectives by eliminating stockpiles of Russian-origin highly enriched uranium (HEU). The RRRFR programme was first conceived during trilateral discussions among the USA, the Russian Federation and the IAEA, initiated in 1999, when participants identified more than 20 research reactors in 17 countries having Russian/Soviet supplied fuel. In 2000, the Director General of the IAEA sent a letter to 15 countries asking for their willingness to return HEU spent fuel to the Russian Federation. Fourteen countries responded positively to the Director General's letter. In 2004, the Russian Federation and the USA signed a Government-to-Government Agreement concerning cooperation to return the Russian produced research reactor nuclear fuel to the Russian Federation. This agreement established the legal framework necessary for the cooperation between the Russian Federation and the USA for the return of Russian supplied research reactor fuel from eligible countries. Under the Bratislava agreements concluded by Presidents George W. Bush and Vladimir Putin in February 2005, both countries committed to completing all shipments of Russian-origin HEU spent fuel currently stored outside research reactors by the end of 2010. Up to the time of writing (May 2009) the programme has completed 19 shipments totalling over 838 kg of Russian-origin HEU spent and fresh fuel which has been returned from Bulgaria, the Czech Republic, Germany, Kazakhstan, Latvia, the Libyan Arab Jamahiriya, Poland, Romania, Serbia, Uzbekistan and Vietnam. During this time, the programme successfully removed all HEU from two countries, Latvia and Bulgaria. HEU spent fuel shipments have been the most complex shipments under the RRRFR programme, which will be the focus of this publication. The first shipment of HEU spent fuel from Uzbekistan was completed in January 2006, followed by HEU spent fuel

A Framework for Rigorously Identifying Research Gaps in Qualitative Literature Reviews

DEFF Research Database (Denmark)

Müller-Bloch, Christoph; Kranz, Johann

2015-01-01

Identifying research gaps is a fundamental goal of literature reviewing. While it is widely acknowledged that literature reviews should identify research gaps, there are no methodological guidelines for how to identify research gaps in qualitative literature reviews ensuring rigor and replicability....... Our study addresses this gap and proposes a framework that should help scholars in this endeavor without stifling creativity. To develop the framework we thoroughly analyze the state-of-the-art procedure of identifying research gaps in 40 recent literature reviews using a grounded theory approach....... Based on the data, we subsequently derive a framework for identifying research gaps in qualitative literature reviews and demonstrate its application with an example. Our results provide a modus operandi for identifying research gaps, thus enabling scholars to conduct literature reviews more rigorously...

Identifying research priorities for public health research to address health inequalities: use of Delphi-like survey methods.

Science.gov (United States)

Turner, S; Ollerhead, E; Cook, A

2017-10-09

In the funding of health research and public health research it is vital that research questions posed are important and that funded research meets a research need or a gap in evidence. Many methods are used in the identification of research priorities, however, these can be resource intensive, costly and logistically challenging. Identifying such research priorities can be particularly challenging for complex public health problems as there is a need to consult a number of experts across disciplines and with a range of expertise. This study investigated the use of Delphi-like survey methods in identifying important research priorities relating to health inequalities and framing tractable research questions for topic areas identified. The study was conducted in two phases, both using Delphi-like survey methods. Firstly, public health professionals with an interest in health inequalities were asked to identify research priorities. Secondly academic researchers were asked to frame tractable research questions relating to the priorities identified. These research priorities identified using Delphi-like survey methods were subsequently compared to those identified using different methods. A total of 52 public health professionals and 21 academics across the United Kingdom agreed to take part. The response rates were high, from public health professionals across three survey rounds (69%, 50% and 40%) and from academics across one round (52%), indicating that participants were receptive to the method and motivated to respond. The themes identified as encompassing the most important research priorities were mental health, healthy environment and health behaviours. Within these themes, the topic areas that emerged most strongly included community interventions for prevention of mental health problems and the food and alcohol environment. Some responses received from academic researchers were (as requested) in the form of tractable research questions, whereas others

Stable isotope fingerprinting: a novel method for identifying plant, fungal, or bacterial origins of amino acids

Science.gov (United States)

Thomas Larsen; D. Lee Taylor; Mary Beth Leigh; Diane M. O' Brien

2009-01-01

Amino acids play an important role in ecology as essential nutrients for animals and as currencies in symbiotic associations. Here we present a new approach to tracing the origins of amino acids by identifying unique patterns of carbon isotope signatures generated by amino acid synthesis in plants, fungi, and bacteria ("13C fingerprints...

Original Research By Young Twinkle Students(ORBYTS): When can students start performingoriginal research?

Science.gov (United States)

Sousa-Silva, Clara; ORBYTS, Twinkle Space Mission, ExoMol

2018-01-01

Involving students in state-of-the-art research from an early age eliminates the idea that science is only for the scientists and empowers young people to explore STEM (Science, Technology, Engineering and Maths) subjects. It is also a great opportunity to dispel harmful stereotypes about who is suitable for STEM careers, while leaving students feeling engaged in modern science and the scientific method. As part of the Twinkle Space Mission’s educational programme, EduTwinkle, students between the ages of 15 and 18 have been performing original research associated with the exploration of space since January 2016. The student groups have each been led by junior researchers - PhD student and post-doctoral scientists - who themselves benefit substantially from the opportunity to supervise and manage a research project. This research aims to meet a standard for publication in peer-reviewed journals. At present the research of one ORBYTS team has been published in the Astrophysical Journal Supplement Series and another submitted to JQSRT; we expect more papers to follow. Here we outline the necessary steps for a productive scientific collaboration with school children, generalising from the successes and downfalls of the pilot ORBYTS projects.

Originality and the PhD: what is it and how can it be demonstrated?

Science.gov (United States)

Gill, Paul; Dolan, Gina

2015-07-01

To explore the concept of originality in doctoral research and outline ways in which doctoral candidates can begin to identify, formulate and articulate their individual contributions to knowledge. Originality is a major feature of doctoral research but considerable confusion exists regarding what can and cannot constitute originality in the PhD and how the contribution to knowledge can be demonstrated clearly. This is a discussion paper. A review of relevant, published literature relating to originality in the PhD. Many doctoral candidates merely outline why they believe their work to be original, instead of demonstrating critically how and in what way their research makes a meaningful contribution to the body of knowledge. The concept of originality in the PhD is complex and multi-faceted. Identifying and conveying originality in doctoral research takes considerable time, contemplation and effort. This process is, however, integral to the PhD itself, and the skills acquired are essential for post-doctoral development. A good doctoral thesis should clearly outline the different ways in which the work is original. A succinct, focused, critical appraisal of the specific contribution to knowledge is preferable to an exhaustive list.

[Research on the original plants of Xian Zhao Zi (Senshosi)].

Science.gov (United States)

Kotaka, Shuji

2008-01-01

Since the Heian period, Xian Zhao Zi (Senshosi) has been used as part of the ceremony believed to help in a healthy pregnancy and safe birth. The purpose of this report is to consider which plants are original Xian Zhao Zi plants. Past research lists certain plants as Xian Zhao Zi, but it was difficult to draw any conclusions.

Dynamic pricing and learning: Historical origins, current research, and new directions

NARCIS (Netherlands)

den Boer, A.V.

The topic of dynamic pricing and learning has received a considerable amount of attention in recent years, from different scientific communities. We survey these literature streams: we provide a brief introduction to the historical origins of quantitative research on pricing and demand estimation,

Origins of management accounting according to different research approaches

Directory of Open Access Journals (Sweden)

Anna Szychta

2016-07-01

Full Text Available The aim of the article is to specify the causes, places and periods of origin of the application of manage-ment accounting in accordance with the views of the foreign supporters of the four main approaches to research on the development of management accounting. The article highlights the various possibilities of interpretation by historians of past events and processes in the practice of management accounting dependingon the types of sources included in research and conceptual basis for discussion and interpretation of the past. The author uses the review, analysis and synthesis of thoughts and opinions of the authors of select-ed publications from the extensive English-language literature of the subject. This article constitutes an input to the discussion about the need to extend the research in Poland in the area of accounting history, including management accounting history.

Original Research

African Journals Online (AJOL)

home

2014-02-18

Feb 18, 2014 ... Blue method and standard MTT colorimetric method). The Euphorbia ... MATERIALS AND METHODS .... were identified as Oximes, alkenes, aminoacids and aromatic .... and vincristine), which were both obtained from the.

[Origin of the scientific arguments underlying qualitative research].

Science.gov (United States)

Minayo, Maria Cecília de Souza

2017-01-01

This article analyzes the origin of the primary arguments that underpin the qualitative approach, covering the birthplace of comprehensive and dialectical thought in Germany, its expansion into other countries such as France and the United States, and its spread into Latin America. The historical journey of the text starts with the development of modern science, examining the first empirical works in the Chicago School and the subsequent period of ostracism of qualitative research. The text also evidences a revival of comprehensive theoretical and empirical perspectives from the 1960s onwards, accompanying the cultural movement that came to question the great theoretical narratives and give rise to reflections on subjectivity. Theoretically, qualitative approaches are now considered a promising form of knowledge construction within the social and human sciences, with consolidated theories and a process of permanent internal critique. Such consolidation is ensured by the researchers' formation of conferences and university departments, the existence of books for the training of new researchers, and the increased presence of relevant spaces in scientific journals.

Customer Satisfaction Research: A Case Study of Original Sokos Hotel Olympia Garden

OpenAIRE

Truong, Thuan

2016-01-01

This thesis research was carried out at Original Sokos Hotel Olympia Garden in summer 2016. The case company is one of three Sokos Hotels located in St. Petersburg, Russia. The hotel aims to deliver a “Cosy living, smart working” environment to all the guests. The thesis project examines customer satisfaction with different service aspects provided at Original Sokos Hotel Olympia Garden and the customers’ willingness to recommend the hotel to others. The thesis also analyzes the factors h...

Original Researc Original Research

African Journals Online (AJOL)

RAGHAVENDRA

2015-03-23

Mar 23, 2015 ... Maize insect pest. *Corresponding Author: Ahmed Ibrahim. E-mail: ibrahimyuya02@gmail.com e methods of storage pest control good for the control of stored sorghum t they were not proved for efficacy. hould be supported by research, as could be very high and for wider of locally available plant products ...

Genetic analysis identifies the region of origin of smuggled peach palm seeds.

Science.gov (United States)

Cristo-Araújo, Michelly; Molles, David Bronze; Rodrigues, Doriane Picanço; Clement, Charles R

2017-04-01

Seeds of a plant, supposedly a palm tree known popularly as peach palm (Bactris gasipaes), were seized by the Federal Police in the state of Pará, Brazil, without documentation of legal origin to authorize transportation and marketing in Brazil. They were alleged to be from the western part of Amazonas, Brazil, near the frontier with Peru and Colombia, justifying the lack of documentation. The species was confirmed to be peach palm. To determine the likely place of origin, a genetic analysis was performed to determine the relationship between the seized seeds and representative populations of peach palm from all of Amazonia, maintained in the Peach palm Core Collection, at the National Research Institute for Amazonia, using nine microsatellite loci. Reynolds' coancestry analysis showed a strong relationship between the seeds and the Pampa Hermosa landrace, around Yurimaguas, Peru. The Structure program, used to infer the probability of an individual belonging to a given population, showed that most seeds grouped with populations close to Yurimaguas, Peru, corroborating the coancestry analysis. The Pampa Hermosa landrace is the main source of spineless peach palm seeds used in the Brazilian heart-of-palm agribusiness, which motivated the smugglers to attempt this biopiracy. Copyright © 2017 Elsevier B.V. All rights reserved.

Identifying the material of original and restored parts of a 14^{th} century alabaster annunciation group through stable isotopes

Science.gov (United States)

Kloppmann, Wolfram; Leroux, Lise; Le Pogam, Pierre-Yves; Bromblet, Philippe

2017-04-01

The origin of raw materials for sculpture is often obscure before the 17th century due to the scarcity of written sources. Identifying this origin provides hints to economic exchanges but also, potentially, allows for attributing sculptures to a specific context of creation (regional workshops, artists). Another challenge for art historians is the identification of restorations and their potential chronology. We present an example of a 14th century group of two statues, made of gypsum alabaster, representing an annunciation group, with the Virgin Mary and the angel Gabriel. Their original position was a near Troyes in the eastern Paris Basin, they are now separated being conserved at the Louvre Museum (Virgin Mary) and the Cleveland Museum of Art (Gabriel). Our multi-isotope study revealed the common origin of the material used for both sculptures, their isotope fingerprints being identical within the analytical error. These fingerprints are highly specific and point to an origin in a historical gypsum and alabaster quarry in the northern part of Provence, France, first mentioned at the end of the 13th century. We were also able to identify an unknown restoration of lower part of the Virgin Mary statue with an optically undistinguishable material, using Tuscan alabaster, most likely in the 19th century. This underlines the potential and usefulness of independent geochemical evidence to underpin stylistic hypotheses on grouping of individual artworks, historical economic relationships between regions and on past restoration activities.

Original Researc Original Research

African Journals Online (AJOL)

RAGHAVENDRA

(VSM) measurements. The XRD of Mn-doped ZnO. The crystal size from the XRD was observed to absorption peaks between 200 - 600 cm-1. TM doped ZnO nanocrystals shows weak ferromagn well known that, ZnO has large band gap energy abo region. TM doped ZnO nanocrystals have further research work, we plan to ...

EZID: Long term identifiers made easy (Invited)

Science.gov (United States)

Starr, J.

2013-12-01

Scholarly research is producing ever increasing amounts of digital research data, and this data should be managed throughout the research life cycle both as part of good scientific practice, but also to comply with funder mandates, such as the 2013 OSTP Public Access Memo (http://www.whitehouse.gov/sites/default/files/microsites/ostp/ostp_public_access_memo_2013.pdf). By assigning unique and persistent identifiers to data objects, data managers can gain control and flexibility over what can be a daunting task. This is due to the fact that the objects can be moved to new locations without disruption to links, as long as the identifier target is maintained. EZID is a tool that makes assigning and maintaining unique, persistent identifiers easy. It was designed and built by California Digital Library (CDL) and has both a user interface and a RESTful API. EZID currently offers services for two globally unique, persistent identifier schemes: Digital Object Identifiers (DOIs) and Archival Resource Keys (ARKs). DOIs are identifiers originating from the publishing world and are in widespread use for journal articles. CDL is able to offer DOIs because of being a founding member of DataCite (http://www.datacite.org/), an international consortium established to provide easier access to scientific research data on the Internet. ARKs are identifiers originating from the library, archive and museum community. Like DOIs, they become persistent when the objects and identifier forwarding information is maintained. DOIs and ARKs have a key role in data management and, therefore, in data management plans. DOIs are the recommended identifier for use in data citation, and ARKs provide the maximum flexibility needed for data documentation and management throughout the early phases of a project. The two identifier schemes are able to be used together, and EZID is made to work with both. EZID clients, coming from education, research, government, and the private sector, are utilizing the

Original Research

African Journals Online (AJOL)

2013-09-27

Sep 27, 2013 ... DNA sequences were masked using CENSOR. The multiple sequence analysis revealed nine highly conserved regions of similarities in the 5'- flanking region of butyrophilin genes across species. Consensus putative transcription factor binding sites were identified using MatInspector and compared with ...

[Research and investigation on original plants of medicinal Moutan].

Science.gov (United States)

Peng, Hua-Sheng; Wang, De-Qun; Peng, Dai-Yin; Huang, Lu-Qi

2017-05-01

As a kind of famous ornamental flowers, Moutan, known as "the king of flower", mainly originates from various cultivars of Paeonia suffruticosa. Moutan Cortex, a common traditional Chinese medicine, has a long medicinal history for more than 2 000 years. At present, "Fengdanpi", which is the root bark of P. ostii mainly growing in Tongling, Anhui, is a sort of Dao-di herbs in traditional Chinese medicine. However,various editions of Chinese pharmacopoeia has been stipulating that Moutan Cortex originates from the bark root of P. suffruticosa. Textual researches on germplasm of ornamental and medicinal Moutan provided that, Xi'an, Luoyang, Pengcheng, Bozhou, Heze and some other famous cultivation centers had been formed throughout the history. In addition, medicinal practitioners in Song Dynasty had been fully aware of the medicinal differences between ornamental and wild Moutan, and preferred wild single flowers as medicinal Moutan. Moreover, none of cultivation centers of ornamental Moutan were recorded in producing areas of medicinal Moutan. So far, Fengdan and Dianjiang Moutan in Chongqing are single flowers, which is consistent with the ancient herbal books. Therefore, this paper believes that the medicinal and ornamental Moutan are two different germplasm since ancient times. And we proposethat Chinese pharmacopoeia should record P. ostii and the single-flower varieties of P. suffruticosa as the original plants of Moutan Cortex. Copyright© by the Chinese Pharmaceutical Association.

Importance of the Country of Origin from the Consumers’ Perspective in the Research Context of Bosnia and Herzegovina

Directory of Open Access Journals (Sweden)

Marija Čutura

2016-06-01

Full Text Available Purpose – The purpose of this paper is to establish the level of importance of the country of origin (COO in the purchasing process of different categories of consumer goods in the research context of Bosnia and Herzegovina (B&H. Design/Methodology/Approach – The study is based on primary data collected through a survey questionnaire on a consumer sample in B&H. The analysis consists of several levels: establishing a level of COO importance for consumers; establishing a level of consumer familiarity with a COO; identifying the influence of consumer ethnocentrism on the level of COO importance. Findings and implications – ANOVA and T-paired tests highlighted the importance of COO to vary across product categories. The results of regression analysis showed that consumer ethnocentrism significantly influences the level of COO importance in the purchasing process. The results contribute to the thesis that COO has a diagnostic value for the consumers in the purchasing process and can therefore be used as a marketing tool in providing better market acceptance and positioning of products. Limitations – This research has a limited scope considering that it is a single-market study, but also because of the small range of researched product categories. Further research studies should consider a wider range of product categories, as well as a cross-cultural research approach to explore the importance of COO on the overall purchasing process. Originality – This study represents an integrative approach to the phenomenon of COO, consisting of consumer ethnocentrism, product characteristics, and consumer perspective regarding COO importance and familiarity.

H-index in medicine is driven by original research.

Science.gov (United States)

Nowak, Jan K; Lubarski, Karol; Kowalik, Lukasz M; Walkowiak, Jaroslaw

2018-02-28

To investigate the contribution of selected types of articles to h-indices of medical researchers. We used the Web of Science to export the publication records of various members from 26 scientific medical societies (13 European, 13 North American) associated with 13 medical specialties. Those included were presidents (n=26), heads of randomly chosen committees (n=52), and randomly selected members of those committees (n=52). Publications contributing to h-index were categorized as research articles, reviews, guidelines, meta-analyses, or other published work. Overall, 3259 items authored by 129 scholars were analyzed. The median h-index was 19.5. The median contribution of research articles to h-index was 84.4%. Researchers in the upper h-index tercile (≥28.5) had a larger share of research articles that contributed to h-index in comparison with those in the lower h-index tercile (≤12.5) (median 87.3% [1st-3rd quartile: 80.0%-93.1%] vs 80.0% [50.0%-88.9%], P=0.015). We observed an analogous difference with regard to guidelines (1.1% [0%-3.7%] vs 0% [0%-0%], P=0.007). Original research drives h-indices in medicine. Although guidelines contribute to h-indices in medicine, their influence is low. The specific role of randomized controlled trials in building h-index in medicine remains to be assessed.

Original Research

African Journals Online (AJOL)

2012-12-15

Dec 15, 2012 ... Science, Technology and Arts Research Journal. Oct-Dec 2012 ... Teachers' Perceptions and Practices of Active Learning in Haramaya ..... Third, data gathering tools ... from the numerical values assigned to the degree.

Original Research

African Journals Online (AJOL)

2013-09-24

Sep 24, 2013 ... the observers' lacks of visual research skills, they pay an equal attention to physical and social ... fewer comments' of observers on visual irregularities and diffusions in managing signboards, urban graffiti ..... narrative. Visual ...

Identifying subgroups of CERME affect research papers

OpenAIRE

Hannula, Markku S.; Garcia Moreno-Esteva, Enrique

2017-01-01

Research in mathematics related affect uses a variety of theoretical frameworks. Three different dimensions have been suggested as significant to characterize concepts in this area: (1) emotional, motivational, and cognitive aspects of affect, (2) state and trait aspects of affect, and (3) physiological, psychological, and sociological level of theorizing affect. In this study, we used the information in reference lists and graph theory to identify Graph Communities (coherent clusters) of res...

Original Research

African Journals Online (AJOL)

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2014-12-19

Dec 19, 2014 ... Science, Technology and Arts Research Journal ... The Relationship between Students' Perceived EFL Classroom Climate and ... classroom climate and their achievement in English language. .... learning. Furthermore, the finding may give teacher ..... effects on mathematics achievement of fourth-grade.

Original Research

African Journals Online (AJOL)

2012-12-29

Dec 29, 2012 ... and Anna C. Treydte1. 1 Agroecology in the Tropics ... Post Box No: 05, Ethiopia. 3 Adami Tulu Agricultural Research Centre, Ziway, Post Box No: 35, Ethiopia .... meat as food resource, oxen for draught power and equines for ...

Toward sustainable environmental quality: Identifying priority research questions for Latin America

Science.gov (United States)

Furley, Tatiana Heid; Brodeur, Julie; Silva de Assis, Helena C; Carriquiriborde, Pedro; Chagas, Katia R; Corrales, Jone; Denadai, Marina; Fuchs, Julio; Mascarenhas, Renata; Miglioranza, Karina SB; Miguez Caramés, Diana Margarita; Navas, José Maria; Nugegoda, Dayanthi; Planes, Estela; Rodriguez‐Jorquera, Ignacio Alejandro; Orozco‐Medina, Martha; Boxall, Alistair BA; Rudd, Murray A

2018-01-01

ABSTRACT The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research questions that would represent priority needs to address in the region. One hundred questions were received, then partitioned among categories, examined, and some rearranged during a workshop in Buenos Aires, Argentina. Twenty priority research questions were subsequently identified. These research questions included developing, improving, and harmonizing across LA countries methods for 1) identifying contaminants and degradation products in complex matrices (including biota); 2) advancing prediction of contaminant risks and effects in ecosystems, addressing lab‐to‐field extrapolation challenges, and understanding complexities of multiple stressors (including chemicals and climate change); and 3) improving management and regulatory tools toward achieving sustainable development. Whereas environmental contaminants frequently identified in these key questions were pesticides, pharmaceuticals, endocrine disruptors or modulators, plastics, and nanomaterials, commonly identified environmental challenges were related to agriculture, urban effluents, solid wastes, pulp and paper mills, and natural extraction activities. Several interesting research topics included assessing and preventing pollution impacts on conservation protected areas, integrating environment and health assessments, and developing strategies for identification, substitution, and design of less hazardous chemicals (e.g., green chemistry). Finally, a recurrent research need included developing an understanding of differential sensitivity of regional species and ecosystems to environmental contaminants and other stressors. Addressing these critical

Toward sustainable environmental quality: Identifying priority research questions for Latin America.

Science.gov (United States)

Furley, Tatiana Heid; Brodeur, Julie; Silva de Assis, Helena C; Carriquiriborde, Pedro; Chagas, Katia R; Corrales, Jone; Denadai, Marina; Fuchs, Julio; Mascarenhas, Renata; Miglioranza, Karina Sb; Miguez Caramés, Diana Margarita; Navas, José Maria; Nugegoda, Dayanthi; Planes, Estela; Rodriguez-Jorquera, Ignacio Alejandro; Orozco-Medina, Martha; Boxall, Alistair Ba; Rudd, Murray A; Brooks, Bryan W

2018-05-01

The Global Horizon Scanning Project (GHSP) is an innovative initiative that aims to identify important global environmental quality research needs. Here we report 20 key research questions from Latin America (LA). Members of the Society of Environmental Toxicology and Chemistry (SETAC) LA and other scientists from LA were asked to submit research questions that would represent priority needs to address in the region. One hundred questions were received, then partitioned among categories, examined, and some rearranged during a workshop in Buenos Aires, Argentina. Twenty priority research questions were subsequently identified. These research questions included developing, improving, and harmonizing across LA countries methods for 1) identifying contaminants and degradation products in complex matrices (including biota); 2) advancing prediction of contaminant risks and effects in ecosystems, addressing lab-to-field extrapolation challenges, and understanding complexities of multiple stressors (including chemicals and climate change); and 3) improving management and regulatory tools toward achieving sustainable development. Whereas environmental contaminants frequently identified in these key questions were pesticides, pharmaceuticals, endocrine disruptors or modulators, plastics, and nanomaterials, commonly identified environmental challenges were related to agriculture, urban effluents, solid wastes, pulp and paper mills, and natural extraction activities. Several interesting research topics included assessing and preventing pollution impacts on conservation protected areas, integrating environment and health assessments, and developing strategies for identification, substitution, and design of less hazardous chemicals (e.g., green chemistry). Finally, a recurrent research need included developing an understanding of differential sensitivity of regional species and ecosystems to environmental contaminants and other stressors. Addressing these critical questions will

Original Research

African Journals Online (AJOL)

2012-02-18

Feb 18, 2012 ... Science, Technology and Arts Research Journal. Jan-March 2012, 1(1): ... simultaneously, this paper presents a novel iris recognition method based on the natural-open eyes. ... information, length information, width information of texture, the neighbouring ... Non-contacting biometrics is the inevitable trend.

Original Research

African Journals Online (AJOL)

2013-09-20

Sep 20, 2013 ... Science, Technology and Arts Research Journal ... water quality parameters were analyzed using the membrane filtration method. Water ... is the first line of defense against water borne .... MATERIALS AND METHODS .... acid and distilled water. ... supply and sanitation laboratory for microbiological water ...

The origins of biopolitics as a new direction of research within the national political science

Directory of Open Access Journals (Sweden)

Anastasiya Y. Kravets

2016-02-01

Full Text Available The origins of biopolitics as a new scientific discipline is the main aim of the article. There is no clear vision of biopolitics origins among scientific community: some biopolitics see them in the evolution of biological knowledge, others – in the political concepts. The article represents comprehensive approach to this scientific problem and includes philosophical, biological, political and psychological origins of biopolitics, which helps clarify the scientific knowledge about the subject and scientific interest of this discipline. Biopolitics isinterdisciplinary branch of knowledge, which combines multitude of researching trends. In case we’re going to use biopolitical researching for political analysis: background and evolution of human political behaviour, psycho-physiological aspects of such behaviour, function of upbringing and social norms in transformation of social behaviour and later on the political one, influence of the political behaviour to political process and so on. Thus biopolitics could be defined in context of political discourse as related discipline researching «homo politicus» as biological species with emphasis to psycho-physiological mechanisms of political behaviour and theirs influence to political process.

Original Research

African Journals Online (AJOL)

2013-12-27

Dec 27, 2013 ... performance of the synthesizer was evaluated using accuracy as ... further research in the area, especially with the aim of developing a full- ... information and knowledge on a long term-basis and ... morphological processing systems such as morphological .... can combine to form variants of words.

Original Research

African Journals Online (AJOL)

Science, Technology and Arts Research Journal. July-Sep 2012, 1(3): 08-16 ... Revised :25-09-2012. Accepted :28-09- ..... vegetables, leaves, nuts, seeds, barks, roots and in other parts. ... antioxidant capacities of human plasma and natural compounds ... membrane lipid peroxidation and as peroxyl radical scavengers.

Life support decision making in critical care: Identifying and appraising the qualitative research evidence.

Science.gov (United States)

Giacomini, Mita; Cook, Deborah; DeJean, Deirdre

2009-04-01

The objective of this study is to identify and appraise qualitative research evidence on the experience of making life-support decisions in critical care. In six databases and supplementary sources, we sought original research published from January 1990 through June 2008 reporting qualitative empirical studies of the experience of life-support decision making in critical care settings. Fifty-three journal articles and monographs were included. Of these, 25 reported prospective studies and 28 reported retrospective studies. We abstracted methodologic characteristics relevant to the basic critical appraisal of qualitative research (prospective data collection, ethics approval, purposive sampling, iterative data collection and analysis, and any method to corroborate findings). Qualitative research traditions represented include grounded theory (n = 15, 28%), ethnography or naturalistic methods (n = 15, 28%), phenomenology (n = 9, 17%), and other or unspecified approaches (n = 14, 26%). All 53 documents describe the research setting; 97% indicate purposive sampling of participants. Studies vary in their capture of multidisciplinary clinician and family perspectives. Thirty-one (58%) report research ethics board review. Only 49% report iterative data collection and analysis, and eight documents (15%) describe an analytically driven stopping point for data collection. Thirty-two documents (60%) indicated a method for corroborating findings. Qualitative evidence often appears outside of clinical journals, with most research from the United States. Prospective, observation-based studies follow life-support decision making directly. These involve a variety of participants and yield important insights into interactions, communication, and dynamics. Retrospective, interview-based studies lack this direct engagement, but focus on the recollections of fewer types of participants (particularly patients and physicians), and typically address specific issues (communication and

Using Latent Semantic Analysis to Identify Research Trends in OpenStreetMap

Directory of Open Access Journals (Sweden)

Sukhjit Singh Sehra

2017-07-01

Full Text Available OpenStreetMap (OSM, based on collaborative mapping, has become a subject of great interest to the academic community, resulting in a considerable body of literature produced by many researchers. In this paper, we use Latent Semantic Analysis (LSA to help identify the emerging research trends in OSM. An extensive corpus of 485 academic abstracts of papers published during the period 2007–2016 was used. Five core research areas and fifty research trends were identified in this study. In addition, potential future research directions have been provided to aid geospatial information scientists, technologists and researchers in undertaking future OSM research.

Original Research

African Journals Online (AJOL)

home

2014-08-21

Aug 21, 2014 ... Science, Technology and Arts Research Journal. Sci. Technol. ..... from poor to wealthier, in which 7(5.8%) farmers were poor ... type/cultivar of mango grown by small holder farmers was ... mango farm land witnessed, for first time this insect pest ..... Ethiopia to East Wollega, Guto Gida district, Loko village.

Original Research

African Journals Online (AJOL)

2013-09-24

Sep 24, 2013 ... the observers' lacks of visual research skills, they pay an equal attention to physical and social environment even in the absence of social activity facts in the photos. I argued that students used their mental image and memories of the urban space in commentaries about each photos. Besides, they used ...

Quantitative phase-digital holographic microscopy: a new imaging modality to identify original cellular biomarkers of diseases

KAUST Repository

Marquet, P.

2016-05-03

Quantitative phase microscopy (QPM) has recently emerged as a powerful label-free technique in the field of living cell imaging allowing to non-invasively measure with a nanometric axial sensitivity cell structure and dynamics. Since the phase retardation of a light wave when transmitted through the observed cells, namely the quantitative phase signal (QPS), is sensitive to both cellular thickness and intracellular refractive index related to the cellular content, its accurate analysis allows to derive various cell parameters and monitor specific cell processes, which are very likely to identify new cell biomarkers. Specifically, quantitative phase-digital holographic microscopy (QP-DHM), thanks to its numerical flexibility facilitating parallelization and automation processes, represents an appealing imaging modality to both identify original cellular biomarkers of diseases as well to explore the underlying pathophysiological processes.

Identifying future research directions for biodiversity, ecosystem services and sustainability : perspectives from early-career researchers

NARCIS (Netherlands)

Hossain, S.; Pogue, S.J.; Trenchard, L.; Oudenhoven, van A.P.E.; Washbourne, C-L.; Muiruri, E.W.; Tomczyk, A.M.; García-Llorente, M.; Hale, R.; Hevia, V.; Adams, T.; Tavallali, L.; De, Bell S.; Pye, M.; Resende, F.

2017-01-01

We aimed to identify priority research questions in the field of biodiversity, ecosystem services and sustainability (BESS), based on a workshop held during the NRG BESS Conference for Early Career Researchers on BESS, and to compare these to existing horizon scanning exercises. This work highlights

2011 Origins of Solar Systems Gordon Research Conference %A Ryan Gray, Nancy

Science.gov (United States)

This proposal requests funding of $30,000 from NASA to support registration and/or travel costs of participants, such as but not limited to world-renown experts and/or young scientists (postdocs, graduate students, etc.) new to the field, who would not otherwise we able to participate in the Gordon Research Conference (GRC) on the Origins of Solar Systems. The past ten GRCs on this topic have fueled the rapid progress of discovery and ignited new areas of inquiry within this theme. The “Origins” GRC is the only forum that brings together the required expertise, at the correct frequency, on a consistent basis in the field today. The goals of this meeting are directly aligned with the strategic goals of NASA (by historical design). The opportunity for professional development for graduate students and young researchers in this interdisciplinary area are unique. We believe NASA Origins support is vital to the long-term success of this meeting series and the role it plays in the success of the “Origins” program overall.

Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs.

Directory of Open Access Journals (Sweden)

Delphine Fradin

2010-09-01

Full Text Available Autism is a common heritable neurodevelopmental disorder with complex etiology. Several genome-wide linkage and association scans have been carried out to identify regions harboring genes related to autism or autism spectrum disorders, with mixed results. Given the overlap in autism features with genetic abnormalities known to be associated with imprinting, one possible reason for lack of consistency would be the influence of parent-of-origin effects that may mask the ability to detect linkage and association.We have performed a genome-wide linkage scan that accounts for potential parent-of-origin effects using 16,311 SNPs among families from the Autism Genetic Resource Exchange (AGRE and the National Institute of Mental Health (NIMH autism repository. We report parametric (GH, Genehunter and allele-sharing linkage (Aspex results using a broad spectrum disorder case definition. Paternal-origin genome-wide statistically significant linkage was observed on chromosomes 4 (LOD(GH = 3.79, empirical p<0.005 and LOD(Aspex = 2.96, p = 0.008, 15 (LOD(GH = 3.09, empirical p<0.005 and LOD(Aspex = 3.62, empirical p = 0.003 and 20 (LOD(GH = 3.36, empirical p<0.005 and LOD(Aspex = 3.38, empirical p = 0.006.These regions may harbor imprinted sites associated with the development of autism and offer fruitful domains for molecular investigation into the role of epigenetic mechanisms in autism.

Gene expression profiles help identify the Tissue of Origin for metastatic brain cancers

Directory of Open Access Journals (Sweden)

VandenBerg Scott R

2010-04-01

Full Text Available Abstract Background Metastatic brain cancers are the most common intracranial tumor and occur in about 15% of all cancer patients. In up to 10% of these patients, the primary tumor tissue remains unknown, even after a time consuming and costly workup. The Pathwork® Tissue of Origin Test (Pathwork Diagnostics, Redwood City, CA, USA is a gene expression test to aid in the diagnosis of metastatic, poorly differentiated and undifferentiated tumors. It measures the expression pattern of 1,550 genes in these tumors and compares it to the expression pattern of a panel of 15 known tumor types. The purpose of this study was to evaluate the performance of the Tissue of Origin Test in the diagnosis of primary sites for metastatic brain cancer patients. Methods Fifteen fresh-frozen metastatic brain tumor specimens of known origins met specimen requirements. These specimens were entered into the study and processed using the Tissue of Origin Test. Results were compared to the known primary site and the agreement between the two results was assessed. Results Fourteen of the fifteen specimens produced microarray data files that passed all quality metrics. One originated from a tissue type that was off-panel. Among the remaining 13 cases, the Tissue of Origin Test accurately predicted the available diagnosis in 12/13 (92.3% cases. Discussion This study demonstrates the accuracy of the Tissue of Origin Test when applied to predict the tissue of origin of metastatic brain tumors. This test could be a very useful tool for pathologists as they classify metastatic brain cancers.

Identifying and Researching Market Opportunities for New High Technology Products.

Science.gov (United States)

Dunstan, Peter

Using a product called the synchro-pulse welder as a case study example, this paper discusses the activities of CSIRO (Commonwealth Scientific and Industrial Research Organisation) in identifying and marketing new high-technology products. A general discussion of CSIRO's market research plans includes two goals to be attained within the next 5…

Conducting Original, Hands-On Astronomical Research in the Classroom

Science.gov (United States)

Corneau, M. J.

2009-12-01

teachers to convey moderately complex computer science, optical, geographic, mathematical, informational and physical principles through hands-on telescope operations. In addition to the general studies aspects of classroom internet-based astronomy, Tzec Maun supports real science by enabling operators precisely point telescopes and acquire extremely faint, magnitude 19+ CCD images. Thanks to the creative Team of Photometrica (photometrica.org), my teams now have the ability to process and analyze images online and produce results in short order. Normally, astronomical data analysis packages cost greater than thousands of dollars for single license operations. Free to my team members, Photometrica allows students to upload their data to a cloud computing server and read precise photometric and/or astrometric results. I’m indebted to Michael and Geir for their support. The efficacy of student-based research is well documented. The Council on Undergraduate Research defines student research as, "an inquiry or investigation conducted by an undergraduate that makes an original intellectual or creative contribution to the discipline." (http://serc.carleton.edu/introgeo/studentresearch/What. Teaching from Tzec Maun in the classroom is the most original teaching research I can imagine. I very much look forward to presenting this program to the convened body.

Research Priorities for Fertility and Conception Research as Identified by Multidisciplinary Health Care Practitioners and Researchers

Directory of Open Access Journals (Sweden)

Lisa J. Moran

2016-01-01

Full Text Available The Robinson Research Institute of the University of Adelaide convened a multidisciplinary group of n = 33 clinicians, researchers and representatives of government organisations on the 2 October 2014 for a workshop entitled “Promoting fertility and healthy conception. How do we generate greater reproductive health awareness?” The key aim of the workshop was to assess the body of knowledge that informs clinical practice and government policy, and to identify questions and additional information needed by health practitioners and government representatives working in the field of reproductive health and to frame future research and policy. The workshop identified topics that fell mostly into three categories: lifestyle-related, societal and biological factors. The lifestyle topics included nutrition and diet, exercise, obesity, shift work and other factors deemed to be modifiable at the level of the individual. The societal topics included discussions of matters that are structural, and resistant to change by individuals, including specific ethical issues, social disadvantage, government and educational policies. The biological factors are intrinsic physical states of the individual, and included many factors where there is a dense body of scientific knowledge which may not be readily accessible in less academic language. This workshop thus provided an opportunity to identify further actions that could be undertaken to meet the needs of diverse organisations and groups of professionals with an interest in human fertility. Since so many factors in our social and biological environment can impact fertility and preconception health, it is imperative to involve many disciplines or levels of government or societal organisations that have not traditionally been involved in this area.

Using a research framework to identify knowledge gaps in research on food marketing to children in Australia.

Science.gov (United States)

Chapman, Kathy; Kelly, Bridget; King, Lesley

2009-06-01

Research in the field of food marketing to children requires a better understanding of the research gaps in order to inform policy development. The purpose of this paper was to propose a framework for classifying food marketing research, using Australian research on food marketing to children to demonstrate how this framework can be used to determine knowledge gaps. A literature review of research databases and 'grey' material was conducted to identify research from the previous 10 years. Studies were classified according to their research focus, and media type, as either: exposure, including content analyses; effects of exposure, including opinions, attitudes and actions resulting from food marketing exposure; regulations, including the type and level of regulation that applies to food marketing; or breaches of regulations, including instances where marketing regulations have been violated. The majority of Australian research on food marketing to children has focused on television advertising and exposure research. Research has consistently shown that the content of food marketing directed at children is predominately for unhealthy foods. There is a lack of research on the effects of food marketing, which would be valuable to inform policy. The development of a logical framework for food marketing research allows for the identification of research gaps and enables research priorities to be identified.

Recruitment strategies and costs associated with community-based research in a Mexican-origin population.

Science.gov (United States)

Mendez-Luck, Carolyn A; Trejo, Laura; Miranda, Jeanne; Jimenez, Elizabeth; Quiter, Elaine S; Mangione, Carol M

2011-06-01

We describe the recruitment strategies and personnel and materials costs associated with two community-based research studies in a Mexican-origin population. We also highlight the role that academic-community partnerships played in the outreach and recruitment process for our studies. We reviewed study documents using case study methodology to categorize recruitment methods, examine community partnerships, and calculate study costs. We employed several recruitment methods to identify and solicit 154 female caregivers for participation in qualitative interviews and quantitative surveys. Recruitment approaches included using flyers and word of mouth, attending health fairs, and partnering with nonprofit community-based organizations (CBOs) to sponsor targeted recruitment events. Face-to-face contact with community residents and partnerships with CBOs were most effective in enrolling caregivers into the studies. Almost 70% of participants attended a recruitment event sponsored or supported by CBOs. The least effective recruitment strategy was the use of flyers, which resulted in only 7 completed interviews or questionnaires. Time and costs related to carrying out the research varied by study, where personal interviews cost more on a per-participant basis ($1,081) than the questionnaires ($298). However, almost the same amount of time was spent in the community for both studies. Partnerships with CBOs were critical for reaching the target enrollment for our studies. The relationship between the University of California-Los Angeles (UCLA) Resource Center for Minority Aging Research/Center for Health Improvement for Minority Elderly and the Department of Aging provided the infrastructure for maintaining connections with academic-community partnerships. Nevertheless, building partnerships required time, effort, and resources for both researchers and local organizations.

Recruitment Strategies and Costs Associated With Community-Based Research in a Mexican-Origin Population

Science.gov (United States)

Mendez-Luck, Carolyn A.; Trejo, Laura; Miranda, Jeanne; Jimenez, Elizabeth; Quiter, Elaine S.; Mangione, Carol M.

2011-01-01

Purpose: We describe the recruitment strategies and personnel and materials costs associated with two community-based research studies in a Mexican-origin population. We also highlight the role that academic–community partnerships played in the outreach and recruitment process for our studies. We reviewed study documents using case study methodology to categorize recruitment methods, examine community partnerships, and calculate study costs. Results: We employed several recruitment methods to identify and solicit 154 female caregivers for participation in qualitative interviews and quantitative surveys. Recruitment approaches included using flyers and word of mouth, attending health fairs, and partnering with nonprofit community-based organizations (CBOs) to sponsor targeted recruitment events. Face-to-face contact with community residents and partnerships with CBOs were most effective in enrolling caregivers into the studies. Almost 70% of participants attended a recruitment event sponsored or supported by CBOs. The least effective recruitment strategy was the use of flyers, which resulted in only 7 completed interviews or questionnaires. Time and costs related to carrying out the research varied by study, where personal interviews cost more on a per-participant basis ($1,081) than the questionnaires ($298). However, almost the same amount of time was spent in the community for both studies. Implications: Partnerships with CBOs were critical for reaching the target enrollment for our studies. The relationship between the University of California–Los Angeles (UCLA) Resource Center for Minority Aging Research/Center for Health Improvement for Minority Elderly and the Department of Aging provided the infrastructure for maintaining connections with academic–community partnerships. Nevertheless, building partnerships required time, effort, and resources for both researchers and local organizations. PMID:21565824

Foreign research reactor spent nuclear fuel inventories containing HEU and LEU of US-origin

International Nuclear Information System (INIS)

Matos, J.E.

1995-01-01

This paper provides estimates of the quantities and types of foreign research reactor spent nuclear fuel containing HEU and LEU of US-origin that are anticipated during the period beginning in January 1996 and extending for 10-15 years

Developing a matrix to identify and prioritise research recommendations in HIV Prevention

Directory of Open Access Journals (Sweden)

Coates Bob

2011-05-01

Full Text Available Abstract Background HIV prevention continues to be problematic in the UK, as it does globally. The UK Department of Health has a strategic direction with greater focus on prevention as part of its World Class Commissioning Programme. There is a need for targeted evidence-based prevention initiatives. This is an exploratory study to develop an evidence mapping tool in the form of a matrix: this will be used to identify important gaps in contemporary HIV prevention evidence relevant to the UK. It has the potential to aid prioritisation in future research. Methods Categories for prevention and risk groups were developed for HIV prevention in consultation with external experts. These were used as axes on a matrix tool to map evidence. Systematic searches for publications on HIV prevention were undertaken using electronic databases for primary and secondary research undertaken mainly in UK, USA, Canada, Australia and New Zealand, 2006-9. Each publication was screened for inclusion then coded. The risk groups and prevention areas in each paper were counted: several publications addressed multiple risk groups. The counts were exported to the matrix and clearly illustrate the concentrations and gaps of literature in HIV prevention. Results 716 systematic reviews, randomised control trials and other primary research met the inclusion criteria for HIV prevention. The matrix identified several under researched areas in HIV prevention. Conclusions This is the first categorisation system for HIV prevention and the matrix is a novel tool for evidence mapping. Some important yet under-researched areas have been identified in HIV prevention evidence: identifying the undiagnosed population; international adaptation; education; intervention combinations; transgender; sex-workers; heterosexuals and older age groups. Other research recommendations: develop the classification system further and investigate transferability of the matrix to other prevention areas

IDENTIFYING FRACTURE ORIGIN IN CERAMICS BY COMBINATION OF NONDESTRUCTIVE TESTING AND DISCRETE ELEMENT ANALYSIS

International Nuclear Information System (INIS)

Senapati, Rajeev; Zhang Jianmei

2010-01-01

Advanced ceramic materials have been extensively applied in aerospace, automobile and other industries. However, the reliability of the advanced ceramics is a major concern because of the brittle nature of the materials. In this paper, combination of nondestructive testing and numerical modeling Discrete Element Method is proposed to identify the fracture origin in ceramics. The nondestructive testing--laser scattering technology is first performed on the ceramic components to reveal the machining-induced damage such as cracks and the material-inherent flaws such as voids, then followed by the four point bending test. Discrete Element software package PFC 2D is used to simulate the four point bending test and try to identify where the fractures start. The numerical representation of the ceramic materials is done by generating a densely packed particle system using the specimen genesis procedure and then applying the suitable microparameters to the particle system. Simulation of four point bending test is performed on materials having no defects, materials having manufacturing-induced defects like cracks, and materials having material-inherent flaws like voids. The initiation and propagation of defects is modeled and the mean contact force on the loading ball is also plotted. The simulation prediction results are well in accordance with the nondestructive testing results.

Identifying the origin of underground water in the Andean Cordillera

International Nuclear Information System (INIS)

Rodriguez, C.O.

1979-01-01

Two problems associated with groundwater flow were fully identified by the application of geochemical techniques. The first was related to the Palacio tunnel, where infiltration of 400 litres/min caused caving-in and other problems which held up construction for several months. To anticipate further problems and to plan the requisite engineering work, a study was carried out to locate the origin of the groundwater responsible for these difficulties. Water samples were taken from the four possible sources: a pool, a series of large fissures, superficial fluvioglacial deposits and the Guadalupe sandstone which crops out one kilometre from the cave-in site. After correlation of the results of chemical analyses with geological and hydrological information about the area, the conclusion was reached that the groundwater in question flows from the Guadalupe sandstone through fractures and secondary openings. The second problem studied was that of the immense Quebradablanca landslide caused by infiltration of water into and percolation through alluvial deposits. A drainage system had already been designed to intercept and collect direct infiltration water above the alluvium, thereby preventing the latter from becoming saturated. The present study was carried out to determine whether there was groundwater flow from the rocks adjacent to the alluvium. The results of the geochemical analysis indicate that most of the water does in fact come from the adjacent hard rock rather than from direct infiltration of rain-water above the alluvium. This shows that the drainage system designed is insufficient for preventing saturation of the rock and that a more extensive and costly system would be needed to control the groundwater flow. (author)

Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq).

Science.gov (United States)

Langley, Alexander R; Gräf, Stefan; Smith, James C; Krude, Torsten

2016-12-01

Next-generation sequencing has enabled the genome-wide identification of human DNA replication origins. However, different approaches to mapping replication origins, namely (i) sequencing isolated small nascent DNA strands (SNS-seq); (ii) sequencing replication bubbles (bubble-seq) and (iii) sequencing Okazaki fragments (OK-seq), show only limited concordance. To address this controversy, we describe here an independent high-resolution origin mapping technique that we call initiation site sequencing (ini-seq). In this approach, newly replicated DNA is directly labelled with digoxigenin-dUTP near the sites of its initiation in a cell-free system. The labelled DNA is then immunoprecipitated and genomic locations are determined by DNA sequencing. Using this technique we identify >25,000 discrete origin sites at sub-kilobase resolution on the human genome, with high concordance between biological replicates. Most activated origins identified by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4) motifs. They tend to cluster in early-replicating domains, providing a correlation between early replication timing and local density of activated origins. Origins identified by ini-seq show highest concordance with sites identified by SNS-seq, followed by OK-seq and bubble-seq. Furthermore, germline origins identified by positive nucleotide distribution skew jumps overlap with origins identified by ini-seq and OK-seq more frequently and more specifically than do sites identified by either SNS-seq or bubble-seq. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Steroid compounds of phytogenic origin: scientometric research data of scientific and practical literature

Directory of Open Access Journals (Sweden)

Sukhanov А.Е.

2017-03-01

Full Text Available Steroid compounds of phytogenic origin are important in clinical medicine rendering anti-inflammatory, anti-prolifer-ative and antithrombotic actions. However, steroid compounds of phytogenic origin, in particular, steroid saponins are insufficiently studied from an identification position in tissues of vegetable organisms and methods of their physical and chemical analysis. The scientometric analysis of research data (abstract documents containing an analytical array of scientific publications concerning isolation, selection, cleaning, identification and the quantitative definition of steroid saponins in tissues of the higher vascular plants in the abstract bibliographic database SciVerse Scopus (Elsevier publishing house with use of criteria "key word" and "the key phrase" is provided in the article.

Songs composed for use in music therapy: a survey of original songwriting practices of music therapists.

Science.gov (United States)

Jones, Jennifer D

2006-01-01

While researchers have documented the efficacy of clinical songwriting in music therapy, limited research has been conducted on songs composed by music therapists that address clinical goals. The purpose of this research was to examine the original songwriting practices of music therapists. Professional music therapists (N = 1,364) received a 14-question survey via email asking each to identify client populations and clinical goals addressed by original songs, their length of time in clinical practice, and specifics about their acquisition of songwriting skills. The data collected from 302 completed surveys revealed that respondents who used original songs were most likely to work with children and adolescents in schools or the developmental disability field and wrote songs in order to individualize treatment. Music therapists working with persons over 65 years of age in long term care or assisted living programs were the least likely to use original songs in clinical practice, opting for interventions utilizing the client's familiar music. Most music therapists found songwriting generally easy, but only 37% indicated that they acquired this skill during their undergraduate degree. Additional research on the clinical efficacy of original songs and therapist's compositional processes is needed to identify best practices models for strategic songwriting.

Planetary Environments and Origins of Life

Directory of Open Access Journals (Sweden)

Ollivier Marc

2014-02-01

Full Text Available The present strategies proposed for the search for the origins of life and for extra-terrestrial life are mainly based on Earth-life and its adaptation along geological eras to the Earth environment. These strategies should however face the difficulty that one cannot as yet accurately date the appearance of life on Earth, and consequently one cannot identify a chronology of phenomena related to the transition from the non-living to the living and the dependence of these phenomena on the Earth environment. In this paper, we present new approaches to search for the origins of life on the Earth and next, for life on exoplanets. This study is based on our experience gained at the head of the CNRSc interdisciplinary research initiative "Environnements Planétaires et Origines de la Vie (EPOVd, and on the analysis of the projects the initiative funded.

TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

DEFF Research Database (Denmark)

Marquard, Andrea Marion; Birkbak, Nicolai Juul; Thomas, Cecilia Engel

2015-01-01

A substantial proportion of cancer cases present with a metastatic tumor and require further testing to determine the primary site; many of these are never fully diagnosed and remain cancer of unknown primary origin (CUP). It has been previously demonstrated that the somatic point mutations......-copy-number classifier on three independent data sets: 1669 newly available public tumors of various types, a cohort of 91 breast metastases, and a set of 24 specimens from 9 lung cancer patients subjected to multiregion sequencing. The cross-validation accuracy was highest when all three types of information were used...... detected in a tumor can be used to identify its site of origin with limited accuracy. We hypothesized that higher accuracy could be achieved by a classification algorithm based on the following feature sets: 1) the number of nonsynonymous point mutations in a set of 232 specific cancer-associated genes, 2...

In silico reversal of repeat-induced point mutation (RIP identifies the origins of repeat families and uncovers obscured duplicated genes

Directory of Open Access Journals (Sweden)

Hane James K

2010-11-01

Full Text Available Abstract Background Repeat-induced point mutation (RIP is a fungal genome defence mechanism guarding against transposon invasion. RIP mutates the sequence of repeated DNA and over time renders the affected regions unrecognisable by similarity search tools such as BLAST. Results DeRIP is a new software tool developed to predict the original sequence of a RIP-mutated region prior to the occurrence of RIP. In this study, we apply deRIP to the genome of the wheat pathogen Stagonospora nodorum SN15 and predict the origin of several previously uncharacterised classes of repetitive DNA. Conclusions Five new classes of transposon repeats and four classes of endogenous gene repeats were identified after deRIP. The deRIP process is a new tool for fungal genomics that facilitates the identification and understanding of the role and origin of fungal repetitive DNA. DeRIP is open-source and is available as part of the RIPCAL suite at http://www.sourceforge.net/projects/ripcal.

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains

KAUST Repository

Preston, Mark D.

2014-06-13

Malaria is a major public health problem that is actively being addressed in a global eradication campaign. Increased population mobility through international air travel has elevated the risk of re-introducing parasites to elimination areas and dispersing drug-resistant parasites to new regions. A simple genetic marker that quickly and accurately identifies the geographic origin of infections would be a valuable public health tool for locating the source of imported outbreaks. Here we analyse the mitochondrion and apicoplast genomes of 711 Plasmodium falciparum isolates from 14 countries, and find evidence that they are non-recombining and co-inherited. The high degree of linkage produces a panel of relatively few single-nucleotide polymorphisms (SNPs) that is geographically informative. We design a 23-SNP barcode that is highly predictive (?92%) and easily adapted to aid case management in the field and survey parasite migration worldwide. 2014 Macmillan Publishers Limited. All rights reserved.

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains

KAUST Repository

Preston, Mark D.; Campino, Susana; Assefa, Samuel A.; Echeverry, Diego F.; Ocholla, Harold; Amambua-Ngwa, Alfred; Stewart, Lindsay B.; Conway, David J.; Borrmann, Steffen; Michon, Pascal; Zongo, Issaka; Oué draogo, Jean-Bosco; Djimde, Abdoulaye A.; Doumbo, Ogobara K.; Nosten, Francois; Pain, Arnab; Bousema, Teun; Drakeley, Chris J.; Fairhurst, Rick M.; Sutherland, Colin J.; Roper, Cally; Clark, Taane G.

2014-01-01

Malaria is a major public health problem that is actively being addressed in a global eradication campaign. Increased population mobility through international air travel has elevated the risk of re-introducing parasites to elimination areas and dispersing drug-resistant parasites to new regions. A simple genetic marker that quickly and accurately identifies the geographic origin of infections would be a valuable public health tool for locating the source of imported outbreaks. Here we analyse the mitochondrion and apicoplast genomes of 711 Plasmodium falciparum isolates from 14 countries, and find evidence that they are non-recombining and co-inherited. The high degree of linkage produces a panel of relatively few single-nucleotide polymorphisms (SNPs) that is geographically informative. We design a 23-SNP barcode that is highly predictive (?92%) and easily adapted to aid case management in the field and survey parasite migration worldwide. 2014 Macmillan Publishers Limited. All rights reserved.

Development of a framework to identify research gaps from systematic reviews.

Science.gov (United States)

Robinson, Karen A; Saldanha, Ian J; McKoy, Naomi A

2011-12-01

Our objective was to develop a framework to identify research gaps from systematic reviews. We reviewed the practices of (1) evidence-based practice centers (EPCs), and (2) other organizations that conduct evidence syntheses. We developed and pilot tested a framework for identifying research gaps. Four (33%) EPCs and three (8%) other organizations reported using an explicit framework to determine research gaps. Variations of the PICO (population, intervention, comparison, outcomes) framework were most common. We developed a framework incorporating both the characterization of the gap using PICOS elements (also including setting) and the identification of the reason(s) why the gap exists as (1) insufficient or imprecise information, (2) biased information, (3) inconsistency or unknown consistency, and (4) not the right information. We mapped each of these reasons to concepts from three common evidence-grading systems. Our framework determines from systematic reviews where the current evidence falls short and why or how the evidence falls short. This explicit identification of research gaps will allow systematic reviews to maximally inform the types of questions that need to be addressed and the types of studies needed to address the research gaps. Copyright © 2011 Elsevier Inc. All rights reserved.

Identifying future research directions for biodiversity, ecosystem services and sustainability: perspectives from early-career researchers

OpenAIRE

Hossain, S.; Pogue, S.J.; Trenchard, L.; Oudenhoven, van, A.P.E.; Washbourne, C-L.; Muiruri, E.W.; Tomczyk, A.M.; García-Llorente, M.; Hale, R.; Hevia, V.; Adams, T.; Tavallali, L.; De, Bell S.; Pye, M.; Resende, F.

2017-01-01

We aimed to identify priority research questions in the field of biodiversity, ecosystem services and sustainability (BESS), based on a workshop held during the NRG BESS Conference for Early Career Researchers on BESS, and to compare these to existing horizon scanning exercises. This work highlights the need for improved data availability through collaboration and knowledge exchange, which, in turn, can support the integrated valuation and sustainable management of ecosystems in response to g...

Recruitment Strategies and Costs Associated with Community-Based Research in a Mexican-Origin Population

Science.gov (United States)

Mendez-Luck, Carolyn A.; Trejo, Laura; Miranda, Jeanne; Jimenez, Elizabeth; Quiter, Elaine S.; Mangione, Carol M.

2011-01-01

Purpose: We describe the recruitment strategies and personnel and materials costs associated with two community-based research studies in a Mexican-origin population. We also highlight the role that academic-community partnerships played in the outreach and recruitment process for our studies. We reviewed study documents using case study…

Original Research Article

African Journals Online (AJOL)

Erah

Complement system and immunoglobulin classes (IgG, IgA and IgM) ... Immunology Research and. Training Unit, College ... and possible autoimmune disorder in HIV patients ... circulating immune complexes [2, 6, 7], which ... abnormal liver functions, pathogenic infections .... Basic Immunology for Students of Medicine and.

Setting Priorities for Diabetic Retinopathy Clinical Research and Identifying Evidence Gaps.

Science.gov (United States)

Le, Jimmy T; Hutfless, Susan; Li, Tianjing; Bressler, Neil M; Heyward, James; Bittner, Ava K; Glassman, Adam; Dickersin, Kay

2017-01-01

Prioritizing comparative effectiveness research may contribute to obtaining answers that clinicians perceive they need and may minimize research that could be considered wasteful. Our objective was to identify evidence gaps and set priorities for new systematic reviews and randomized controlled trials for managing diabetic retinopathy (DR), including diabetic macular edema (DME). Cross-sectional study. Diabetic Retinopathy Clinical Research Network (DRCR.net) investigators. We provided recommendations from the American Academy of Ophthalmology's 2012 Preferred Practice Patterns for Diabetic Retinopathy as 91 answerable clinical research questions about intervention effectiveness to 410 DRCR.net investigators to rate each question's importance from 0 (not important) to 10 (very important) using a 2-round Delphi survey and to suggest additional questions. We considered questions as high priority if at least 75% of respondents to both rounds assigned an importance rating of 5 or more in round 2. We also extracted outcome measures relevant to DR and asked respondents to identify those that must be measured in all studies. We mapped Cochrane reviews published up to March 2016 to high-priority clinical research questions. Ranking of importance of each clinical question. Thirty-two individuals completed rounds 1 and 2 and suggested 15 questions. Among the final list of 106 clinical research questions, 22 questions met our definition of high priority: 9 of 22 concerned the effectiveness of anti-VEGF therapy, and 13 of 22 focused on how often patients should be followed up (re-examination) and treatment effectiveness in patients with specific characteristics (e.g., DME). Outcomes that 75% or more of respondents marked as "must be measured in all studies" included visual acuity and visual loss, death of participants, and intraocular pressure. Only 1 prioritized question was associated with conclusive evidence from a Cochrane systematic review. A limited response rate among

Adventist Education: origin, development and expasion

Directory of Open Access Journals (Sweden)

Patrick Vieira Ferreira

2018-03-01

Full Text Available This article aimed to present a brief historical report of the origin, development and consolidation of the Adventist Education Network. Thus, it will be possible to know about its emergence, philosophy of education and the genesis of this confessional network operating in the Brazilian educational scenario for more than a century. The research method includes bibliographical analysis of the main theoreticians of the Brazilian history of education and rescues facts cited by Adventist historians. The research situated the Adventist Education Network in the Brazilian historical context and identified the Seventh-day Adventists as a religious group and as agents in the field of school education.

Development and pilot test of a process to identify research needs from a systematic review.

Science.gov (United States)

Saldanha, Ian J; Wilson, Lisa M; Bennett, Wendy L; Nicholson, Wanda K; Robinson, Karen A

2013-05-01

To ensure appropriate allocation of research funds, we need methods for identifying high-priority research needs. We developed and pilot tested a process to identify needs for primary clinical research using a systematic review in gestational diabetes mellitus. We conducted eight steps: abstract research gaps from a systematic review using the Population, Intervention, Comparison, Outcomes, and Settings (PICOS) framework; solicit feedback from the review authors; translate gaps into researchable questions using the PICOS framework; solicit feedback from multidisciplinary stakeholders at our institution; establish consensus among multidisciplinary external stakeholders on the importance of the research questions using the Delphi method; prioritize outcomes; develop conceptual models to highlight research needs; and evaluate the process. We identified 19 research questions. During the Delphi method, external stakeholders established consensus for 16 of these 19 questions (15 with "high" and 1 with "medium" clinical benefit/importance). We pilot tested an eight-step process to identify clinically important research needs. Before wider application of this process, it should be tested using systematic reviews of other diseases. Further evaluation should include assessment of the usefulness of the research needs generated using this process for primary researchers and funders. Copyright © 2013 Elsevier Inc. All rights reserved.

An analysis of trends in globalisation of origin of research published in major general medical journals.

Science.gov (United States)

Falagas, M E; Alexiou, V G

2008-01-01

There is an ongoing discussion in the scientific community that even the leading scientific journals publish mainly research that is produced in the countries where these journals are based. We analysed data regarding the origin of publications in 11 leading general medical journals during the last 35 years: The Lancet, British Medical Journal, Journal of the American Medical Association, New England Journal of Medicine, Annals of Internal Medicine, Archives of Internal Medicine, American Journal of Medicine, Mayo Clinic Proceedings, Canadian Medical Association Journal, Medical Journal of Australia and Journal of Internal Medicine (previously called Acta Medica Scandinavica). Among the examined journals, The Lancet has been the most diverse regarding the origin of publications; in the period 1971-1975, 62.6% of its publications originated from the UK while the relevant figure dropped to 43.2% in the period 2001-2005 (19.4% decrease). During the period 2000-2005, the proportion of publications that originated from the country in which each one of the rest of the examined journals has been based ranged from 71.7% to 95.1%. This figure decreased by a proportion ranging from 10.9% to 19.4% for some major US- and UK-based medical journals during the 35-year study period. Our own interpretation of the findings of this study is that scientific journals will better serve the global scientific community as well as the public by adopting policies that increase the mixture of the origin of research that they publish, including work from scientists in developing countries, especially during the era we live.

A bibliometric model for identifying emerging research topics

DEFF Research Database (Denmark)

Wang, Qi

2018-01-01

–1843, 2015), the most serious problems are the lack of an acknowledged definition of emergence and incomplete elaboration of the linkages between the definitions that are used and the indicators that are created. With these issues in mind, this study first adjusts the definition of an emerging technology...... that Rotolo et al. (2015) have proposed to accommodate the analysis. Next, a set of criteria for the identification of emerging topics is proposed according to the adjusted definition and attributes of emergence. Using two sets of parameter values, several emerging research topics are identified. Finally...

DNA replication origins-where do we begin?

Science.gov (United States)

Prioleau, Marie-Noëlle; MacAlpine, David M

2016-08-01

For more than three decades, investigators have sought to identify the precise locations where DNA replication initiates in mammalian genomes. The development of molecular and biochemical approaches to identify start sites of DNA replication (origins) based on the presence of defining and characteristic replication intermediates at specific loci led to the identification of only a handful of mammalian replication origins. The limited number of identified origins prevented a comprehensive and exhaustive search for conserved genomic features that were capable of specifying origins of DNA replication. More recently, the adaptation of origin-mapping assays to genome-wide approaches has led to the identification of tens of thousands of replication origins throughout mammalian genomes, providing an unprecedented opportunity to identify both genetic and epigenetic features that define and regulate their distribution and utilization. Here we summarize recent advances in our understanding of how primary sequence, chromatin environment, and nuclear architecture contribute to the dynamic selection and activation of replication origins across diverse cell types and developmental stages. © 2016 Prioleau and MacAlpine; Published by Cold Spring Harbor Laboratory Press.

Identifying the Research Process to Analyse the Adoption of the International Baccalaureate's Diploma Programme in England

Science.gov (United States)

Outhwaite, Deborah

2018-01-01

This article analyses the flow-line around the methodology used inside an educational research process that was originally established to examine the expansion of the International Baccalaureate's Diploma Programme (IBDP) in England. This article analyses the research question, then assesses the research focus, aims and objectives. The article…

Gender Differences in the Authorship of Original Research in Pediatric Journals, 2001-2016.

Science.gov (United States)

Fishman, Michael; Williams, Wadsworth A; Goodman, Denise M; Ross, Lainie Friedman

2017-12-01

To examine the gender of authors of original research in 3 high-impact pediatric journals between 2001 and 2016, given the importance of publishing on academic promotion, and to compare authorship gender with the percentage of women on editorial boards and with academic faculty composition. We assessed the prevalence of female first and senior (last-listed) authorship of original research articles published in 3 pediatric-focused journals Pediatrics, JAMA Pediatrics (entitled Archives of Pediatric and Adolescent Medicine until 2013), and The Journal of Pediatrics. We also examined the gender breakdown of the main editors and the broader editorial boards of these journals. In addition, we examined whether junior female faculty co-authored with male or female senior faculty. Of 3895 original articles, 22 were excluded because the gender of either the first or senior author could not be determined from the name. An analysis of authorship by year showed increasing female representation across the selected journals in both first (39.8% in 2001, 57.7% in 2016) and senior (28.6% in 2001, 38.1% in 2016) authors, respectively. Editorial boards also showed increasing female representation (17.8% in 2001 to 39.8% in 2016). Junior female faculty were more likely to co-author with senior female women (female first and last author); the gap remained unchanged despite the increasing number of women entering pediatrics. Women are underrepresented as authors and editors, although the gap is closing. Junior women are less likely to co-author with senior men, which may be a disservice given current gender disparities in promotion and leadership. Copyright © 2017 Elsevier Inc. All rights reserved.

Strategies to design clinical studies to identify predictive biomarkers in cancer research.

Science.gov (United States)

Perez-Gracia, Jose Luis; Sanmamed, Miguel F; Bosch, Ana; Patiño-Garcia, Ana; Schalper, Kurt A; Segura, Victor; Bellmunt, Joaquim; Tabernero, Josep; Sweeney, Christopher J; Choueiri, Toni K; Martín, Miguel; Fusco, Juan Pablo; Rodriguez-Ruiz, Maria Esperanza; Calvo, Alfonso; Prior, Celia; Paz-Ares, Luis; Pio, Ruben; Gonzalez-Billalabeitia, Enrique; Gonzalez Hernandez, Alvaro; Páez, David; Piulats, Jose María; Gurpide, Alfonso; Andueza, Mapi; de Velasco, Guillermo; Pazo, Roberto; Grande, Enrique; Nicolas, Pilar; Abad-Santos, Francisco; Garcia-Donas, Jesus; Castellano, Daniel; Pajares, María J; Suarez, Cristina; Colomer, Ramon; Montuenga, Luis M; Melero, Ignacio

2017-02-01

The discovery of reliable biomarkers to predict efficacy and toxicity of anticancer drugs remains one of the key challenges in cancer research. Despite its relevance, no efficient study designs to identify promising candidate biomarkers have been established. This has led to the proliferation of a myriad of exploratory studies using dissimilar strategies, most of which fail to identify any promising targets and are seldom validated. The lack of a proper methodology also determines that many anti-cancer drugs are developed below their potential, due to failure to identify predictive biomarkers. While some drugs will be systematically administered to many patients who will not benefit from them, leading to unnecessary toxicities and costs, others will never reach registration due to our inability to identify the specific patient population in which they are active. Despite these drawbacks, a limited number of outstanding predictive biomarkers have been successfully identified and validated, and have changed the standard practice of oncology. In this manuscript, a multidisciplinary panel reviews how those key biomarkers were identified and, based on those experiences, proposes a methodological framework-the DESIGN guidelines-to standardize the clinical design of biomarker identification studies and to develop future research in this pivotal field. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Multimodal shipments under program on Russian-origin research reactor SFA return to Russian Federation

International Nuclear Information System (INIS)

Dorofeev, A.N.; Ivashchenko, A.A.; Kanashov, B.A.; Komarov, S.V.; Komarov, S.N.; Barinkov, O.P.

2010-01-01

The paper describes experience in preparation and organization of research reactor nuclear material import under the Program on Russian-Origin Highly Enriched Uranium Return to the Russian Federation. It also summarizes evolution of transport equipment, conveyances and routes and describes types of packages, their adaptation and certification, safety issues, peculiarities and prospective use of the packagings and conveyances. (author)

Original Misunderstanding

Science.gov (United States)

Holtzman, Alexander

2009-01-01

Humorist Josh Billings quipped, "About the most originality that any writer can hope to achieve honestly is to steal with good judgment." Billings was harsh in his view of originality, but his critique reveals a tension faced by students every time they write a history paper. Research is the essence of any history paper. Especially in high school,…

A Model for Data Citation in Astronomical Research Using Digital Object Identifiers (DOIs)

Science.gov (United States)

Novacescu, Jenny; Peek, Joshua E. G.; Weissman, Sarah; Fleming, Scott W.; Levay, Karen; Fraser, Elizabeth

2018-05-01

Standardizing and incentivizing the use of digital object identifiers (DOIs) to aggregate and identify both data analyzed and data generated by a research project will advance the field of astronomy to match best practices in other research fields like geoscience and medicine. An increase in the use of DOIs will prepare the discipline for changing expectations among funding agencies and publishers, who increasingly expect accurate and thorough data citation to accompany scientific outputs. The use of DOIs ensures a robust, sustainable, and interoperable approach to data citation in which due credit is given to the researchers and institutions who produce and maintain the primary data. We describe in this work the advantages of DOIs for data citation and best practices for integrating a DOI service in an astronomical archive. We report on a pilot project carried out in collaboration with AAS journals. During the course of the 1.5-year long pilot, over 75% of submitting authors opted to use the integrated DOI service to clearly identify data analyzed during their research project when prompted at the time of paper submission.

Original Research Rotavirus antigen, cytokine, and neutralising ...

African Journals Online (AJOL)

Department of Clinical Infection, Microbiology and Immunology; University of Liverpool, Liverpool, United Kingdom. 3. .... onset of illness.10 However, we were unable to find original records and thus ..... position paper, 2013:p. 49–64. 12.

Research Note Identifying key grazing indicators to monitor trends in ...

African Journals Online (AJOL)

Research Note Identifying key grazing indicators to monitor trends in the veld condition of Lambert's Bay Strandveld, South Africa. ... from which a minimum number of species necessary to monitor trends in the condition of the veld were determined, making it user-friendly for land-users, extension officers and others. The key ...

Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication.

Science.gov (United States)

Feng, Wenyi; Collingwood, David; Boeck, Max E; Fox, Lindsay A; Alvino, Gina M; Fangman, Walton L; Raghuraman, Mosur K; Brewer, Bonita J

2006-02-01

During DNA replication one or both strands transiently become single stranded: first at the sites where initiation of DNA synthesis occurs (known as origins of replication) and subsequently on the lagging strands of replication forks as discontinuous Okazaki fragments are generated. We report a genome-wide analysis of single-stranded DNA (ssDNA) formation in the presence of hydroxyurea during DNA replication in wild-type and checkpoint-deficient rad53 Saccharomyces cerevisiae cells. In wild-type cells, ssDNA was first observed at a subset of replication origins and later 'migrated' bi-directionally, suggesting that ssDNA formation is associated with continuously moving replication forks. In rad53 cells, ssDNA was observed at virtually every known origin, but remained there over time, suggesting that replication forks stall. Telomeric regions seemed to be particularly sensitive to the loss of Rad53 checkpoint function. Replication origins in Schizosaccharomyces pombe were also mapped using our method.

Study on the meat isotopic composition for origin identification

Directory of Open Access Journals (Sweden)

Irina Chernukha

2018-03-01

Full Text Available Russian consumer and governmental authorities are equally concerned to know where food products come from. This requires more accurate and specialized methods for the evaluation of geographical location. The following methods are used: chemometrics, histological and histochemical, genomic and proteomic, microbiological, immunochemical and mass spectrometric. Method of stable isotope analysis is becoming increasingly promising nowadays for the identification of meat and meat products' place of origin. The isotope ratios of the four elements - carbon, nitrogen, oxygen and hydrogen, are mainly determined. The method is successfully used to identify a country of origin of wines, juices and water. The aim of the research was to study the stable isotope ratios for pork and beef samples purchased in Moscow supermarkets (Russian Federation. The country of production of meat samples was determined according to specifications and/or labels. The geography of countries of meat samples origin includes Europe, both America continents and Australia. Databases collected by the All-Russian Scientific Research Institute of the Brewing, Non-Alcoholic and Wine Industrywere used for the analysis and interpretation of the results. Values of 13С/12С, δ13С, 18О/16О, δ18О, 2Н/1Н, δ2Н for 30 pork and beef samples from 13 countries were obtained. Differences in stable isotope ratios were found depending on place of origin. The data correlated with the oxygen isotope characteristics for wine, which were in the range from 2.5 to 4.5 ppm. According to the 13С/12С, δ13С results, the assumption was made about a false indication of the region for the beef sample. Despite the fact that beef was labeled as a product of Lithuania, the region of origin was most probably defined as Germany. The studies carried out showed the possibility to identify the region of raw meat origin by the stable isotope ratio.

32 CFR 2001.21 - Original classification.

Science.gov (United States)

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Original classification. 2001.21 Section 2001.21... Markings § 2001.21 Original classification. (a) Primary markings. At the time of original classification... authority. The name and position, or personal identifier, of the original classification authority shall...

Digital identifiers as permanent unique registers for researchers in the university context

Directory of Open Access Journals (Sweden)

Luisa F. Acosta-Ortega

2016-09-01

Full Text Available The increase in the use of Internet and the web allows a wide access to a greater warehouse of information sources in thousand of journals and publications, nets of almost unlimited number of people, computers and opportunities for learning and research without precedents. That makes the correct identification and recovery of scientific production of researchers very difficult. For that reason, during the last years different attemps of different organizations have been made to create a permanent unique register for authors, which permits to identify their articles wherever they are placed and without taking into account the specificity in the author’s name, publishing and  processing practices In data base,  and different bibliographic description styles as well. ORCID (Openn Researcher and Contribution ID is an identifier with the greatest posibilities of becoming universal to achieve visibility and positioning of Latin-American universities in the present international context.

Persistent Identifiers for Field Expeditions: A Next Step for the US Oceanographic Research Fleet

Science.gov (United States)

Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

2016-04-01

Oceanographic research cruises are complex affairs, typically requiring an extensive effort to secure the funding, plan the experiment, and mobilize the field party. Yet cruises are not typically published online as first-class digital objects with persistent, citable identifiers linked to the scientific literature. The Rolling Deck to Repository (R2R; info@rvdata.us) program maintains a master catalog of oceanographic cruises for the United States research fleet, currently documenting over 6,000 expeditions on 37 active and retired vessels. In 2015, R2R started routinely publishing a Digital Object Identifier (DOI) for each completed cruise. Cruise DOIs, in turn, are linked to related persistent identifiers where available including the Open Researcher and Contributor ID (ORCID) for members of the science party, the International Geo Sample Number (IGSN) for physical specimens collected during the cruise, the Open Funder Registry (FundRef) codes that supported the experiment, and additional DOIs for datasets, journal articles, and other products resulting from the cruise. Publishing a persistent identifier for each field expedition will facilitate interoperability between the many different repositories that hold research products from cruises; will provide credit to the investigators who secured the funding and carried out the experiment; and will facilitate the gathering of fleet-wide altmetrics that demonstrate the broad impact of oceanographic research.

Researchers Develop Method to Identify Sparticles in Big Bang Conditions

CERN Multimedia

2008-01-01

Three Northeastern University researchers have proposed a new approach for the highly anticipated discovery of supersymmetric particles, often called sparticles. The methodology, which was published in the December 21 issue of the Physical Review Letters, is based on identifying the hierarchical mass patterns of sparticles, which are assumed to exist in a new class of particle physics theories beyond the Standard Model.

Your name is not good enough: introducing the ORCID researcher identifier at Imperial College London

Directory of Open Access Journals (Sweden)

Torsten Reimer

2015-11-01

Full Text Available The ORCID researcher identifier ensures that research outputs can always reliably be traced back to their authors. ORCID also makes it possible to automate the sharing of research information, thereby increasing data quality, reducing duplication of effort for academics and saving institutions money. In 2014, Imperial College London created ORCID identifiers (iDs for academic and research staff. This article discusses the implementation project in the context of the role of ORCID in the global scholarly communications system. It shows how ORCID can be used to automate reporting, help with research data publication and support open access (OA.

Radiology research in mainland China in the past 10 years: a survey of original articles published in Radiology and European Radiology

International Nuclear Information System (INIS)

Zhang, Long Jiang; Wang, Yun Fei; Yang, Zhen Lu; Lu, Guang Ming; Schoepf, U.J.; Xu, Jiaqian; Li, Enzhong

2017-01-01

To evaluate the features and trends of Radiology research in Mainland China through bibliometric analysis of the original articles published in Radiology and European Radiology (ER) between 2006 and 2015. We reviewed the original articles published in Radiology and ER between 2006 and 2015. The following information was abstracted: imaging subspecialty, imaging technique(s) used, research type, sample size, study design, statistical analysis, study results, funding declarations, international collaborations, number of authors, department and province of the first author. All variables were examined longitudinally over time. Radiology research in Mainland China saw a substantial increase in original research articles published, especially in the last 5 years (P < 0.001). Within Mainland China's Radiology research, neuroradiology, vascular/interventional Radiology, and abdominal Radiology were the most productive fields; MR imaging was the most used modality, and a distinct geographic provenience was observed for articles published in Radiology and ER. Radiology research in Mainland China has seen substantial growth in the past 5 years with neuroradiology, vascular/interventional Radiology, and abdominal Radiology as the most productive fields. MR imaging is the most used modality. Article provenience shows a distinct geographical pattern. (orig.)

Radiology research in mainland China in the past 10 years: a survey of original articles published in Radiology and European Radiology

Energy Technology Data Exchange (ETDEWEB)

Zhang, Long Jiang; Wang, Yun Fei; Yang, Zhen Lu; Lu, Guang Ming [Medical School of Nanjing University, Department of Medical Imaging, Jinling Hospital, Nanjing, Jiangsu (China); Schoepf, U.J. [Medical School of Nanjing University, Department of Medical Imaging, Jinling Hospital, Nanjing, Jiangsu (China); Medical University of South Carolina, Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Charleston, SC (United States); Xu, Jiaqian [Medical University of South Carolina, Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Charleston, SC (United States); Li, Enzhong [National Natural Science Foundation of China, Department of Medical Science, Beijing (China)

2017-10-15

To evaluate the features and trends of Radiology research in Mainland China through bibliometric analysis of the original articles published in Radiology and European Radiology (ER) between 2006 and 2015. We reviewed the original articles published in Radiology and ER between 2006 and 2015. The following information was abstracted: imaging subspecialty, imaging technique(s) used, research type, sample size, study design, statistical analysis, study results, funding declarations, international collaborations, number of authors, department and province of the first author. All variables were examined longitudinally over time. Radiology research in Mainland China saw a substantial increase in original research articles published, especially in the last 5 years (P < 0.001). Within Mainland China's Radiology research, neuroradiology, vascular/interventional Radiology, and abdominal Radiology were the most productive fields; MR imaging was the most used modality, and a distinct geographic provenience was observed for articles published in Radiology and ER. Radiology research in Mainland China has seen substantial growth in the past 5 years with neuroradiology, vascular/interventional Radiology, and abdominal Radiology as the most productive fields. MR imaging is the most used modality. Article provenience shows a distinct geographical pattern. (orig.)

Identifying research priorities for effective retention strategies in clinical trials.

Science.gov (United States)

Kearney, Anna; Daykin, Anne; Shaw, Alison R G; Lane, Athene J; Blazeby, Jane M; Clarke, Mike; Williamson, Paula; Gamble, Carrol

2017-08-31

The failure to retain patients or collect primary-outcome data is a common challenge for trials and reduces the statistical power and potentially introduces bias into the analysis. Identifying strategies to minimise missing data was the second highest methodological research priority in a Delphi survey of the Directors of UK Clinical Trial Units (CTUs) and is important to minimise waste in research. Our aim was to assess the current retention practices within the UK and priorities for future research to evaluate the effectiveness of strategies to reduce attrition. Seventy-five chief investigators of NIHR Health Technology Assessment (HTA)-funded trials starting between 2009 and 2012 were surveyed to elicit their awareness about causes of missing data within their trial and recommended practices for improving retention. Forty-seven CTUs registered within the UKCRC network were surveyed separately to identify approaches and strategies being used to mitigate missing data across trials. Responses from the current practice surveys were used to inform a subsequent two-round Delphi survey with registered CTUs. A consensus list of retention research strategies was produced and ranked by priority. Fifty out of seventy-five (67%) chief investigators and 33/47 (70%) registered CTUs completed the current practice surveys. Seventy-eight percent of trialists were aware of retention challenges and implemented strategies at trial design. Patient-initiated withdrawal was the most common cause of missing data. Registered CTUs routinely used newsletters, timeline of participant visits, and telephone reminders to mitigate missing data. Whilst 36 out of 59 strategies presented had been formally or informally evaluated, some frequently used strategies, such as site initiation training, have had no research to inform practice. Thirty-five registered CTUs (74%) participated in the Delphi survey. Research into the effectiveness of site initiation training, frequency of patient contact

Economic Education within the BME Research Community: Rejoinder to "Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory"

Science.gov (United States)

Asarta, Carlos J.

2016-01-01

Carlos Asarta comments here that Arbaugh, Fornaciari, and Hwang (2016) are to be commended for their work ("Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory" "Journal of Management Education," Dec 2016, see EJ1118407). Asarta says that they make several…

The risk of re-identification versus the need to identify individuals in rare disease research.

Science.gov (United States)

Hansson, Mats G; Lochmüller, Hanns; Riess, Olaf; Schaefer, Franz; Orth, Michael; Rubinstein, Yaffa; Molster, Caron; Dawkins, Hugh; Taruscio, Domenica; Posada, Manuel; Woods, Simon

2016-11-01

There is a growing concern in the ethics literature and among policy makers that de-identification or coding of personal data and biospecimens is not sufficient for protecting research subjects from privacy invasions and possible breaches of confidentiality due to the possibility of unauthorized re-identification. At the same time, there is a need in medical science to be able to identify individual patients. In particular for rare disease research there is a special and well-documented need for research collaboration so that data and biosamples from multiple independent studies can be shared across borders. In this article, we identify the needs and arguments related to de-identification and re-identification of patients and research subjects and suggest how the different needs may be balanced within a framework of using unique encrypted identifiers.

40 CFR 52.2386 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan... from the original approval of Regulation 5-231(3)(b) into the Vermont SIP identified at subparagraph (c...

Top IS research on quality of transaction standards: a structured literature review to identify a research gap

OpenAIRE

Folmer, E.J.A.; Berends, W.; Oude Luttighuis, P.; Hillegersberg, J. van

2009-01-01

This paper contains the results of a systematic literature review executed to determine the coverage of transaction standards in top information systems (IS) and management journals. Specifically, it aims to identify a research gap with respect to this topic. The top 25 journals are thoroughly searched and the selected publications are classified in order to make grounded statements. A moderate amount of literature found specifically aims at transaction standards. Hardly any research is found...

Identifying multiple submissions in Internet research: preserving data integrity.

Science.gov (United States)

Bowen, Anne M; Daniel, Candice M; Williams, Mark L; Baird, Grayson L

2008-11-01

Internet-based sexuality research with hidden populations has become increasingly popular. Respondent anonymity may encourage participation and lower social desirability, but associated disinhibition may promote multiple submissions, especially when incentives are offered. The goal of this study was to identify the usefulness of different variables for detecting multiple submissions from repeat responders and to explore incentive effects. The data included 1,900 submissions from a three-session Internet intervention with a pretest and three post-test questionnaires. Participants were men who have sex with men and incentives were offered to rural participants for completing each questionnaire. The final number of submissions included 1,273 "unique", 132 first submissions by "repeat responders" and 495 additional submissions by the "repeat responders" (N = 1,900). Four categories of repeat responders were identified: "infrequent" (2-5 submissions), "persistent" (6-10 submissions), "very persistent" (11-30 submissions), and "hackers" (more than 30 submissions). Internet Provider (IP) addresses, user names, and passwords were the most useful for identifying "infrequent" repeat responders. "Hackers" often varied their IP address and identifying information to prevent easy identification, but investigating the data for small variations in IP, using reverse telephone look up, and patterns across usernames and passwords were helpful. Incentives appeared to play a role in stimulating multiple submissions, especially from the more sophisticated "hackers". Finally, the web is ever evolving and it will be necessary to have good programmers and staff who evolve as fast as "hackers".

FACEBOOK for CoP of Researchers: Identifying the Needs and Evaluating the Compatibility

Directory of Open Access Journals (Sweden)

Sami Miniaoui

2011-11-01

Full Text Available Communities of practice (CoPs are increasingly capturing the interest of many fields such as business companies, education and organizations. Many CoPs were developed for people who have common interest in healthcare, agriculture and environment, and teaching. However, there is lack of COPs dedicated for researchers. This research aims to explore the appropriateness of Facebook (FB as a platform for serving a CoP of researchers. To achieve this goal, first we identify the needs of CoPs for researchers within UAE context. Consequently, we adopted qualitative research approach to elicit the needs. We applied the grounded theory method to analyze the data. The results of the analysis showed seven main needs: collaboration, debating, awareness/ notification, reference management, cross search, customization, tracking, and user orientation. Secondly, we evaluated the compatibility of FB features to the identified needs. Although we found that FB covers most of CoPs needs, there are few needs which are not met successfully so this raised some technical and practical issues, which have been highlighted in the paper.

Strategic field No.5 'the origin of matter and the universe'. Toward interdisciplinary researches in particle, nuclear and astrophysics

International Nuclear Information System (INIS)

Aoki, Shinya

2011-01-01

Four main research subjects in the strategic field No. 5 'The origin of matter and the universe', planned to be investigated on 'Kei' super computer, are explained in detail, by focusing on interdisciplinary aspect of researches among particle, nuclear and astrophysics. (author)

Radiology research in mainland China in the past 10 years: a survey of original articles published in Radiology and European Radiology.

Science.gov (United States)

Zhang, Long Jiang; Wang, Yun Fei; Yang, Zhen Lu; Schoepf, U Joseph; Xu, Jiaqian; Lu, Guang Ming; Li, Enzhong

2017-10-01

To evaluate the features and trends of Radiology research in Mainland China through bibliometric analysis of the original articles published in Radiology and European Radiology (ER) between 2006 and 2015. We reviewed the original articles published in Radiology and ER between 2006 and 2015. The following information was abstracted: imaging subspecialty, imaging technique(s) used, research type, sample size, study design, statistical analysis, study results, funding declarations, international collaborations, number of authors, department and province of the first author. All variables were examined longitudinally over time. Radiology research in Mainland China saw a substantial increase in original research articles published, especially in the last 5 years (P Radiology research, neuroradiology, vascular/interventional Radiology, and abdominal Radiology were the most productive fields; MR imaging was the most used modality, and a distinct geographic provenience was observed for articles published in Radiology and ER. Radiology research in Mainland China has seen substantial growth in the past 5 years with neuroradiology, vascular/interventional Radiology, and abdominal Radiology as the most productive fields. MR imaging is the most used modality. Article provenience shows a distinct geographical pattern. • Radiology research in Mainland China saw a substantial increase. • Neuroradiology, vascular/interventional Radiology, and abdominal Radiology are the most productive fields. • MRI is the most used modality in Mainland China's Radiology research. • Guangdong, Shanghai, and Beijing are the most productive provinces.

The Halo Model of Origin Images

DEFF Research Database (Denmark)

Josiassen, Alexander; Lukas, Bryan A.; Whitwell, Gregory J.

2013-01-01

National origin has gained importance as a marketing tool for practitioners to sell their goods and services. However, because origin-image research has been troubled by several fundamental limitations, academia has become sceptical of the current status and strategic implications of the concept....... The aim of this paper was threefold, namely, to provide a state-of-the-art review of origin-image research in marketing, develop and empirically test a new origin-image model and, present the implications of the study....

Arts-Based Research: Trojan Horses and Shibboleths. The Liabilities of a Hybrid Research Approach. "What Hath Eisner Wrought?"

Science.gov (United States)

Pariser, David

2009-01-01

The term "arts-based research" has been debated for some time now. In an article strongly in favor of this approach Bean (2007) identifies three species: "Research on the arts (italics in the original) (art history, visual and cultural studies, media studies etc.)...Research for the arts, refers to research into applied techniques, materials and…

Ethical issues in identifying and recruiting participants for familial genetic research.

Science.gov (United States)

Beskow, Laura M; Botkin, Jeffrey R; Daly, Mary; Juengst, Eric T; Lehmann, Lisa Soleymani; Merz, Jon F; Pentz, Rebecca; Press, Nancy A; Ross, Lainie Friedman; Sugarman, Jeremy; Susswein, Lisa R; Terry, Sharon F; Austin, Melissa A; Burke, Wylie

2004-11-01

Family-based research is essential to understanding the genetic and environmental etiology of human disease. The success of family-based research often depends on investigators' ability to identify, recruit, and achieve a high participation rate among eligible family members. However, recruitment of family members raises ethical concerns due to the tension between protecting participants' privacy and promoting research quality, and guidelines for these activities are not well established. The Cancer Genetics Network Bioethics Committee assembled a multidisciplinary group to explore the scientific and ethical issues that arise in the process of family-based recruitment. The group used a literature review as well as expert opinion to develop recommendations about appropriate approaches to identifying, contacting, and recruiting family members. We conclude that there is no single correct approach, but recommend a balanced approach that takes into account the nature of the particular study as well as its recruitment goals. Recruitment of family members should be viewed as part of the research protocol and should require appropriate informed consent of the already-enrolled participant. Investigators should inform prospective participants why they are being contacted, how information about them was obtained, and what will happen to that information if they decide not to participate. The recruitment process should also be sensitive to the fact that some individuals from families at increased genetic risk will have no prior knowledge of their risk status. These recommendations are put forward to promote further discussion about the advantages and disadvantages of various approaches to family-based recruitment. They suggest a framework for considering alternative recruitment strategies and their implications, as well as highlight areas in need of further empirical research. (c) 2004 Wiley-Liss, Inc.

There Is a Significant Discrepancy Between "Big Data" Database and Original Research Publications on Hip Arthroscopy Outcomes: A Systematic Review.

Science.gov (United States)

Sochacki, Kyle R; Jack, Robert A; Safran, Marc R; Nho, Shane J; Harris, Joshua D

2018-06-01

The purpose of this study was to compare (1) major complication, (2) revision, and (3) conversion to arthroplasty rates following hip arthroscopy between database studies and original research peer-reviewed publications. A systematic review was performed using PRISMA guidelines. PubMed, SCOPUS, SportDiscus, and Cochrane Central Register of Controlled Trials were searched for studies that investigated major complication (dislocation, femoral neck fracture, avascular necrosis, fluid extravasation, septic arthritis, death), revision, and hip arthroplasty conversion rates following hip arthroscopy. Major complication, revision, and conversion to hip arthroplasty rates were compared between original research (single- or multicenter therapeutic studies) and database (insurance database using ICD-9/10 and/or current procedural terminology coding terminology) publishing studies. Two hundred seven studies (201 original research publications [15,780 subjects; 54% female] and 6 database studies [20,825 subjects; 60% female]) were analyzed (mean age, 38.2 ± 11.6 years old; mean follow-up, 2.7 ± 2.9 years). The database studies had a significantly higher age (40.6 + 2.8 vs 35.4 ± 11.6), body mass index (27.4 ± 5.6 vs 24.9 ± 3.1), percentage of females (60.1% vs 53.8%), and longer follow-up (3.1 ± 1.6 vs 2.7 ± 3.0) compared with original research (P database studies (P = .029; relative risk [RR], 1.3). There was a significantly higher rate of femoral neck fracture (0.24% vs 0.03%; P database studies. Reoperations occurred at a significantly higher rate in the database studies (11.1% vs 7.3%; P database studies (8.0% vs 3.7%; P Database studies report significantly increased major complication, revision, and conversion to hip arthroplasty rates compared with original research investigations of hip arthroscopy outcomes. Level IV, systematic review of Level I-IV studies. Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights

[The original German scholarly literature of medieval falconry and the history of its scientific research].

Science.gov (United States)

Giese, Martina

2007-01-01

German scholarly literature (Fachliteratur) of the middle ages devoted to falconry falls into two main categories: Translations, mostly of latin works, and original treatises. After a short survey of falconry in the past, this article will discuss the original treatises and the history of their analysis since the 19th century. In this context it will deal with the research of the following scholars: Joseph von Hammer-Purgstall, Anton von Perger, Ernst von Dombrowski, Hermann Werth, Christoph von Biedermann and--most importantly--Kurt Lindner. The appendix contains the editio princeps of the German Münchener Rezeptar I from the codex unicus, München, Universitätsbibliothek, 80 Cod. ms. 354, fol. 31r-33r (dating from the 15th century).

Using mixed methods to identify and answer clinically relevant research questions.

Science.gov (United States)

Shneerson, Catherine L; Gale, Nicola K

2015-06-01

The need for mixed methods research in answering health care questions is becoming increasingly recognized because of the complexity of factors that affect health outcomes. In this article, we argue for the value of using a qualitatively driven mixed method approach for identifying and answering clinically relevant research questions. This argument is illustrated by findings from a study on the self-management practices of cancer survivors and the exploration of one particular clinically relevant finding about higher uptake of self-management in cancer survivors who had received chemotherapy treatment compared with those who have not. A cross-sectional study generated findings that formed the basis for the qualitative study, by informing the purposive sampling strategy and generating new qualitative research questions. Using a quantitative research component to supplement a qualitative study can enhance the generalizability and clinical relevance of the findings and produce detailed, contextualized, and rich answers to research questions that would be unachievable through quantitative or qualitative methods alone. © The Author(s) 2015.

Identifying future research needs in landscape genetics: Where to from here?

Science.gov (United States)

Niko Balkenhol; Felix Gugerli; Sam A. Cushman; Lisette P. Waits; Aurelie Coulon; J. W. Arntzen; Rolf Holderegger; Helene H. Wagner

2009-01-01

Landscape genetics is an emerging interdisciplinary field that combines methods and concepts from population genetics, landscape ecology, and spatial statistics. The interest in landscape genetics is steadily increasing, and the field is evolving rapidly. We here outline four major challenges for future landscape genetic research that were identified during an...

Identifying the barriers to conducting outcomes research in integrative health care clinic settings - a qualitative study

Directory of Open Access Journals (Sweden)

Findlay-Reece Barbara

2010-01-01

Full Text Available Abstract Background Integrative health care (IHC is an interdisciplinary blending of conventional medicine and complementary and alternative medicine (CAM with the purpose of enhancing patients' health. In 2006, we designed a study to assess outcomes that are relevant to people using such care. However, we faced major challenges in conducting this study and hypothesized that this might be due to the lack of a research climate in these clinics. To investigate these challenges, we initiated a further study in 2008, to explore the reasons why IHC clinics are not conducting outcomes research and to identify strategies for conducting successful in-house outcomes research programs. The results of the latter study are reported here. Methods A total of 25 qualitative interviews were conducted with key participants from 19 IHC clinics across Canada. Basic content analysis was used to identify key themes from the transcribed interviews. Results Barriers identified by participants fell into four categories: organizational culture, organizational resources, organizational environment and logistical challenges. Cultural challenges relate to the philosophy of IHC, organizational leadership and practitioner attitudes and beliefs. Participants also identified significant issues relating to their organization's lack of resources such as funding, compensation, infrastructure and partnerships/linkages. Environmental challenges such as the nature of a clinic's patient population and logistical issues such as the actual implementation of a research program and the applicability of research data also posed challenges to the conduct of research. Embedded research leadership, integration of personal and professional values about research, alignment of research activities and clinical workflow processes are some of the factors identified by participants that support IHC clinics' ability to conduct outcomes research. Conclusions Assessing and enhancing the broader

Identifying research priorities for patient safety in mental health: an international expert Delphi study

Science.gov (United States)

Murray, Kevin; Thibaut, Bethan; Ramtale, Sonny Christian; Adam, Sheila; Darzi, Ara; Archer, Stephanie

2018-01-01

Objective Physical healthcare has dominated the patient safety field; research in mental healthcare is not as extensive but findings from physical healthcare cannot be applied to mental healthcare because it delivers specialised care that faces unique challenges. Therefore, a clearer focus and recognition of patient safety in mental health as a distinct research area is still needed. The study aim is to identify future research priorities in the field of patient safety in mental health. Design Semistructured interviews were conducted with the experts to ascertain their views on research priorities in patient safety in mental health. A three-round online Delphi study was used to ascertain consensus on 117 research priority statements. Setting and participants Academic and service user experts from the USA, UK, Switzerland, Netherlands, Ireland, Denmark, Finland, Germany, Sweden, Australia, New Zealand and Singapore were included. Main outcome measures Agreement in research priorities on a five-point scale. Results Seventy-nine statements achieved consensus (>70%). Three out of the top six research priorities were patient driven; experts agreed that understanding the patient perspective on safety planning, on self-harm and on medication was important. Conclusions This is the first international Delphi study to identify research priorities in safety in the mental field as determined by expert academic and service user perspectives. A reasonable consensus was obtained from international perspectives on future research priorities in patient safety in mental health; however, the patient perspective on their mental healthcare is a priority. The research agenda for patient safety in mental health identified here should be informed by patient safety science more broadly and used to further establish this area as a priority in its own right. The safety of mental health patients must have parity with that of physical health patients to achieve this. PMID:29502096

Original Research Original Research

African Journals Online (AJOL)

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2013-06-23

Jun 23, 2013 ... conomics, College of Business and Economics, Wollega University, ost Box No: ... The Logit model is used to investigate .... providing subsidies, relief, and reducing taxes. The ... the minimum calorie requirement for survival.

Original Research Original Research

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2013-03-24

Mar 24, 2013 ... A major goal in microbial ecology is to link s environmental processes. Solid waste degradatio environmental processes mediated by microorganism the current study an attempt has been made to isol which can degrade the hazardous xenobiotic compou baygon from solid waste by both in vitro and.

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2013-06-26

Jun 26, 2013 ... design problems and the optimization techniques, l used were introduced in this ... nnual system-wide costs and improve service level ase market share. .... losing its sale because the customer may cancel the order or shift to ...

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biotechnologically versatile prokaryotes and produce a number of extracellular ... significantly to the turnover of complex biopolymers such as cellulose, lignin ... microorganisms from the growth of actinomycete isolates. (Gautham, 2012).

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E-mail: andualemtonamo@gm. TAR Journal, Wollega University. All Rights Reserved. ... tropical countries .... agro-ecological zone making totally six kebeles were ... random sampling technique for interview. ... quantitative data between study sites were compared by ...... food and feed production in Wolaita Soddo, Ethiopia.

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gen. The aim of the study was to determine effect of phorus, and sulphur fertilizers on growth, yield, yield of the garlic crop on the two soil types in the study area tments consisted of three .... Soil samples were analyzed at Debre Z. Agricultural .... valued at an average open market price of 10 birr kg-1, cost of Triple Super ...

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Abstract. There is a crucial need for managing the parking spa places, apartments and etc. This is due to an increase i entire world, which actually leads to the rapid increase. However, the availability of parking space is getting lim multi-purpose buildings. Therefore, the aim of this pa microcontroller based automated car ...

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2013-06-20

Jun 20, 2013 ... and knowledge, and gender empowering, changing many ways of acquiring ..... MSEs are the one that hire more labor force, which was about 30% of ...... Empowerment and Income Division Workshop on. Small Enterprises ...

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2013-06-20

Jun 20, 2013 ... cluster analysis were used to assess the patterns of m genotypes into distinct ... Abstract. Article d to evaluate soil acidity tolerance of 25 common bean ..... descriptors and found that the first three components were responsible for 37% of the total variation and that 23 of the 34 descriptors were disposable.

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2013-06-25

Jun 25, 2013 ... Treatments were supplementation of 300 g DM /day o. 100, 75, 50, 25, 0% PJP and ... cass weight (HCW) and rib- eye muscle area (REA) were n the biological ... dry season and the pod can be processed and fed to animals.

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2013-06-26

Jun 26, 2013 ... ost all the organizations in performing their business. The ... ital role in a company's wad and ..... perceived risk of failure, complexity, security, and .... model of technology-based selfservice: moderating ... strategic distribution channel decisions, International ... Managerial Auditing Journal 14(7): 329-338.

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conducted to assess the causes of turnover among the. The study .... reasons the one given most frequently was salary, ... preference of teaching and gender were found to be the ... bored with extra load to cover the gap created by turnover.

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Language and Art Studies, Institute of Language Studies and Journalism,. Wollega University, Post Box No: 395, Nekemte, Ethiopia ... tudies and Journalism,. Article Information. Article History: Received : 11-04-2015 ..... Teaching by principles: An interactive approach to language pedagogy. New York, NY: Addison.

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flexibility in the timing and pressure control of fuel inje obtain significant ... An increasing demand for diesel engines is growing ... gaining more and more attention during re times. ... Fuel tank. Capacity 15 lit. with glass fuel metering column. 9.

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checklists, and Focus Group Discussion were used .... teacher's scaffolding backed-up by reading strategies can ... participation and interaction of learners. ..... measure the students' reading comprehension. A short reading text (a paragraph) ...

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Article Information s of an English teacher's scaffolding on students' .... Repeated word, phrase, short paragraph reading ... that oral reading fluency can help students group words within a ... measure the overall reading competence (Fuchs et al,. 2001). Hence ... effectively through the ZPD in social interaction with others.

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of plants lies in chemical components cal ... ical screening, content of total phenolics, antifungal and ... provide lead compounds for developing new drugs ..... from extracts and to determine their biological activities. ... Authors also thank Prof.

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glish Language and Literature, University of Gondar, Gondar, Ethiopia ... use. The findings suggest that scaffolding reading enhancing students' oral reading ... children's learning is improving their reading skill s .... passage-reading rate based on books or passages the ... students in constructing knowledge, the teacher.

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to learn in which the members of group work cooperate together to find solution .... Questionnaire is considered to be the most flexible of tools and possesses a ..... that the cooperative arrangements during EFL classroom were grouped based ...

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2013-06-23

Jun 23, 2013 ... 1Department of Botany, DRM Science College, Da. 2Gulbarga University,. 3Department of Biotechnology, G.M. Institute. 4Department of Zoology, Sahyadri Scien. 5Department of Botany, Sahyadri Science Colleg. Abstract. This study was ... They form bulk of food for zooplankton, fishes an other aquatic ...

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, nucleic acids a .... effect of M. umbellatum in normal & alloxan diabetic mice. ..... Proteins contain amino acids which are utilized by ... coagulation, milk clotting and regulation of cell ... normal glucose tolerance and in the release of insulin.

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wholesale trades, 591 retailers, 356 service providers, 100 small ... policy issues should not worry about links is benign .... Such a chain of supply of inputs raised the cost .... symbiotic relationship between vendors ... rs were their customers or.

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2013-06-20

Jun 20, 2013 ... ng in employment creation, saving and income generation, and knowledge, and ... poverty. According to a nationwide survey in 1997 by the Central ...... where living situations of majority people is weak and the number of ...

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2013-03-25

Mar 25, 2013 ... Under drought, F1 generation produced higher seed y indicating the presence hetrosis under the stress condit and 4077, F1 and P1 were found to be the most drough. SER-16 and Melka-Dima X SAB-623 crosses, respec drought stress of these generations was associated stomatal conductance, leaf area ...

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M. stenopetala is a deciduous tree 6-12m tall having more or less 60cm ... elongate, reddish with grayish bloom having grooved .... eastern lowland sites are characterized by hot to wa ..... more valuable than fruit trees due to the higher income.

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antioxidant activity of the stem bark extract was studied assay. Extract was shown to display a dose dependent f diffusion ... thousands of years and plant-based systems continue ... m of the present study was to evaluate in vitro antibacterial.

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local market, Mysore and was authenticated by Dr. Nagamani ... Limit test was carried out in accordance to the OECD guideline ... by Tukey's multiple comparison test. p<0.05 was ..... acid B on an Aβ25–35 peptide-induced mouse model of.

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Practices: Universities in. Faculty of Education and Behavioral Sci ... adequate experience concerning problem-solving teach shows that teachers possess the theories and their a organizing ... Behavioral Science, Bahir Dar University, Bahir Dar, Ethiopia. Abstract ...... Educational Leadership 42(7): 57-60. Haney, J.J. ...

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the global biodiversity hotspots. Western Ghats h number and a variety of plants, anima microorganisms. Many species are endemic to W. Ghats. Microbiological studies have been carr using soils of Western Ghats of Karnataka and the obtained were promising in terms of ability of iso produce bioactive metabolites such as ...

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Eastern Afromontane Hotspot Biodiversity area designated by Conservation International (Williams et al.,. 2004). At the heart of these mountains is the Bale. Mountains National Park (BMNP), which is located at about 400 Km southeast of the capital, Addis Ababa. (OBARD, 2007). The national park covers an area of 2200.

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2013-03-22

Mar 22, 2013 ... with less post deployment defects. Moreover if the de ... cost and time compare to defect recognition and rem focus on finding .... Metrology Agency Automation. System in ... brainstorming session by the working team. Once.

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English well; graduates who join the world of wo to write their own CV ..... chosen for the study purposively because they were new to the schools and ..... Ababa, Semien Hotel. Evans, H. M. (1998). ... the Brink of Collapse. Elanders Gotab AB: ...

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for synthesis of drugs to control infectious diseases. ... new drugs to meet the need for the overgrow population of the world (Abad ... more effective, safer and less toxic alternate options of .... medicines as antimalarial, antihypertensive, against.

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employee retention as well as pulling and pushing factors. ... problems, marriage and inadequate preparation in the .... male and 9 female) First Degree, 9 (7 male and 2 female). MD/MV ... remaining instructors, in both cases, were unmarried.

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real information from others (Fawkner and. 2004). In academic contexts, dishonesty is more th cheating at exam, assignments and papers. It includ cheating, fraud and plagiarism, the theft of ideas a other forms of intellectual properties whether they published or not (Jones, 2011). These dishone behaviors can be committed ...

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2013-03-24

Mar 24, 2013 ... which can degrade the hazardous xenobiotic compou baygon from solid waste by .... found in solid waste are bacteria and fungi. These microorganisms ... collected in a clean plastic and air tight container of 500gm capacity.

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A Peer-reviewed Official Internation. Science, T. Sci. Technol. Feed Resources and Livestock Pro and Mid Altitude Areas of Ho. Oromia Regional Sta. Kassahun Gurmessa1*, Taye Tolema. 1College of Agriculture and Veterinary Medicin. 2School of Animal and Range Sciences, Colle. 3Department of Food Science and ...

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A Peer-reviewed Official Internation. Science, T. Sci. Technol. A Low Cost Microcontroller for Two Ethiopian C. Yenenesh Alemu1, Tsegaye Mamo. Jemal Endris. 1Department of Computer Engineering,. 2Department of Computer Science,. Abstract. Maintaining soil water level is a necessary and pre. Water is the essential ...

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A total of uited for the study from Ethiopian meat and dairy industry. 2014 data records on 4 upgraded genetic groups of ... economic role by generating additional cash inco religious and cultural value. Due to this effect, al .... all the property and resources of the Station were transferred to ILRI which continued to operate with ...

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ic antiretroviral treatments, World Health Organization r all exposed infants to ... eir cell differentiation 4 plus ts. ... service provision was not uniformly initiated at all health facilities. ... or variance inflation rates (VIF) of greater than 10 as indicator ...

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In this rega educational theory has proposed a teaching approa which is called ..... that they serve as major factors in guiding and influencing teachers' thoughts ... cognitive development and language are shaped by a student's interaction with ...

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models over predicted the path losses, while Ericsson. However, Hata, Davidson ... planning tools, required by the radio network designer ... variability in VHF and UHF frequency band ...... Electronics and Computer Science (SCEECS), 2014.

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Argon, G.T. (1986). Estudo geoquimico de metais pesados em sediments da planicie de mare da Enseada das. Garcas. Baia de Sepetiba. RJ.T.Mest., Inst. Quimica,. Univ.fed. Fluminense. 135. Berrow, M.L. and Stein, W.M. (1983). Extraction of metals from soils and sewage by refluxing with aqua regia. Analyst 108: 277-285 ...

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eradicating gender inequalities (Bandura al., 2011; Hoff, 2012). ... norms influence the way men interact with their female partners .... weighted scores were trichotomized into three separate ... the principal investigator for use in the case of someone arriving at ..... As to the limitation of this study, First, being a cross- sectional ...

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n, storage of watermelon, market price of watermelon and ... with marketing of melon include low price and u market ... made use of the traditional tools which limit thei ... -3372 (Online) ..... Note: VS-very serious, SE-serious, LS-less serious.

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Therefore, detailed study is necessary for the d the existing water sources, future water sources select water demand and management options .To achieve. Pressure map, population growth rate, Water quality s on purposive sampling method. The pressure result s distributed equally at higher locations of the supply rese.

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continent for the treatment of different diseases a complaints. In certain .... use of a rotator vapor (Buchi, model R-144, Switzerland) at temperature between ..... indicated that infectious skin disorders are very common in Ethiopia. Thus, the fact ...

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traditional approaches. Writing is a ... ted in English classrooms of the targeted grade level to ... process approach to teach writing in six Hon ... alternative solutions and arriving at supported ... According to this approach, the writing lesson should be.

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This study focused on assessing the perceptions, prac instruction by ... Social Science de teachers teach diversified learners in the same classr ... nd Social Science department teachers. However, most ..... Biology, Physics and Mathematics departments were selected ... Humanities faculty, English and Amharic departments.

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... of the brand or important strategy to select the right medium of adver ... about mobile phones as the latest tools for brand pr grows bigger ... for marketing communication (Barwise. Strong ..... able to view high quality images and videos on.

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probability of wheat yield tends to be relatively low, med influencing ... it is one of the long heat food problems and ..... function, plus random error, is within the range of the cutpoints .... hypothesis that each coefficient is different from zero has.

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2013-06-10

Jun 10, 2013 ... incomplete since only a third of the new smear positive cases are detected annually and thus cannot be relied upon for assessment of TB problem. Moreover ... and foreign-born immigrants from countries with high prevalence of TB. .... generations and TB deaths will rise further, also because of higher ...

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organizing mathematics lessons, classroom managemen. Teachers have also ... method at an average level, their obstruction effect was implied that there are ..... non-significant difference between the expected (12) and the observed (12.35) ...

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Many researc has carried lots of experiment by incorporating GGBS ... ive strength at 15 % GGBS content for M35 and M40 grade eferral mix. ..... Table 9: Compressive Strength of M40 Grade. Grade of. Concrete. Replacement of. Cement by ...

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ground with large lobed leaves, and long twisting tend. (Horsfall ... nation of Some Mechanical Properties of Ugu Seed in Relation to .... based on the shape of the pods which were NHTo-1. (pointed at ... Figure 2: Seeds before drying. Figure 3: ...

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Abstract. Article Informat with graded levels of concentrate mix on feed intake, live ... Barley straw is among the dominant farm animal feeds in the highlands of ..... treatment group. In agreement with the present result, sheep fed faba bean.

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... (fungus) and photobi partners (algae/cyanobacteria) which together form ... Lichens occur in various growth forms such as crusto foliose and .... The control and poisoned (0.5mg extract/ml of medium) Potato ..... International Journal of Pest.

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land use type on soil productivity, the study also involve filled with soil ... l management practices became a great challenge to an production to meet the .... amount of rainfall during autumn season and long rain ... oroughly homogenized before r samples of ... (Data in the same column followed by the same letter are not.

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2013-06-20

Jun 20, 2013 ... Multivariate Analysis of Vegetation Data. Classification by means of hierarchical cluster analysis is the most common multivariate technique to analyze community data. Cluster analysis helps to group a set of observations (here plots or vegetation samples) together based on their attributes or floristic ...

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perception toward the role execution of stakeholders in teachers and .... student teachers face between the in-field and on-campus ... secondary teacher education of Ethiopia, prospective teachers of Bahir Dar ... MATERIALS AND METHODS.

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2013-06-20

Jun 20, 2013 ... Intimate partner violence against women undermine the well-being of women. Thus ...... Dares Salaam, Tanzania (Washington, DC: Horizons. Project/ICRW: 2000): ... GCWA_BG_Violence_en.pdf> [Accessed 11 march. 2008].

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Organics must form an indispensable component o any crop. The present study was designed to stud. (BD) compost on biochemical parameters of soya be and 75th day after sowing. The protein content was m of BD compost) on 30th, 45th, 60th and 75 found to be maximum in T1 (3.5 kg of BD compost) day.

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used for selecting breeding village chicken were plumag comp type (23.3%), breed ... protein, amino acids and energy. In Ethiopia chickens the most widespread and almost every rural family ow chickens, which provide a valuable source of fam protein and income ..... Present Price of Eggs and Laying Hens. The average ...

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Data on canopy characteristics such as plan branch length .... cultivation or greenhouse technology, home gard front door cultivation are a ... gy (automation and gh cultivar ..... farmyard manure, etc. may lose large amounts of nitrogen through ...

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The work aims at developing a strategy for the ide target by analyzing signaling pathways. The strateg and tested in concern with Toll Like Receptor. TLR4 pathway is a major pathway which ge polysaccheride (LPS) stimulus. The work describe potent drug targets by understanding the flow of pathways by representing them ...

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2013-06-07

Jun 7, 2013 ... Hence, this study presents economic performance. Hararghe zone of .... countries where purchasing agricultural land hardly exists but ... rural labor measured in market wage paid of peak seasons can be .... seed quality.

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Abstract. Sukhasarak churna, an ayurvedic formulation, traditiona purifier and liver disorder. The main aim of the study amylase activities aqueous extract of Sukhasarak churn churna was screening for antioxidant activity b scavenging assay, nitric oxide scavenging assay an amylase activity by dinitrosalicylic acid method ...

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management in Bule Hora Woreda so as to enhance th increase the advantages ..... threats to the wetlands and evaluate the impact of wetland changes on local .... (1998), the water, soils, plants, hydrological and ecological characteristics of.

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2012-08-12

Aug 12, 2012 ... The hydrogeological study revea sediment .... literature review, field investigation, and data analysis using ... hydrogeological information, i.e., locating of water points ... models, the geophysical survey was conducted with the ...

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broken cut hock as well as from the act of cutting the practice in .... time to reach slaughter weight and age, hence meat production .... Cut the leg at hock & knee. 5. Flying. 6. ... especially for recovering from bone fracture, and from weakness ...

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2015-09-22

Sep 22, 2015 ... variation in local climate, soil type, and a range of socio the main determinants of the physical ability of crops t ... However, grain yields of both the legumes we time of planting and planting pattern. ..... sorghum, and soybean and cowpea component crops by multiplying the yields with their respective unit ...

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milk, the standard for adequate nutrition value (Upadhyay et al., 2009). QPM varieties have yielded positive results in China, Mexico, and Central America for yield and reduction of wet malnutrition. In Africa, 17(South Africa,. Burkina Faso, Cameroon, Ivory Coast, Ethiopia, Ghana,. Guinea, Kenya, Malawi, Mali, Mozambique, ...

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In view of limited information, in this paper the .... security. Such action also reduces the problem of pesticide residues of health risks, since the frequency ..... Thesis,. Haramaya University, Haramaya, Ethiopia. CSA (Central Statistical Agency).

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expression for propagation of path loss in land and mobile radio services. ... work reviewed; show that empirical path loss models ...... Communications 5(1): 44-51. Ayeni, A.A. ... Journal of Wireless and Mobile Computing 7(6):11. Faruk, N.

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the students and the parents to learning; teachers' tend lack of teachers' ... rtunities and Challenges of Student Centered Approach in ifferent Field Of ... Behavioral Science, Bahir Dar University, Post Box No: 79, Bahir Dar, Ethi. Abstract.

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Items 1 - 6 ... types, entertainments (e.g., music and movies), a business promotion and ... to study students' classroom interaction in EFL speaking ..... Methods of Data Analysis ..... highlight of it and jump over to other content of the daily lesson.

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The chemical ecology of many of the green alg ... tetra hydroxyl octadecane isolated from the green alg. Ulva faciata collected off ... two methods have been used as a primary screen ..... Antimicrobial activity and surface bacterial film in marine.

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2013-03-22

Mar 22, 2013 ... qadirforu@gmail.com group task. ... Then they review these data to determ what caused the ... consequences, and they have the data neede avoid making ... 3327 (Online) esearch .... Continuously in touch with client for exact.

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to write their own CV and application letters for jo. On the same line of ..... multiple choice items. Questionnaire on Teacher Interaction (QTI). Students spend a vast amount of time in school classrooms. Moreover, their perceptions are often based on a large number of ..... better picture of the real interpersonal behavior of the.

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Evaluation of Different Strains of Eri for their Adaptability ... performance compared to other strains in all the locati. Therefore, it is ... significant contribution to the economy of many countr ... green and Eri-marked) eri silkworm strains were ... ope of hope at village level for ..... Proceeding of Regional Seminar on Prospects and.

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recommends early HIV testing for all exposed infants t utilization of and ... enrolled in ART and/or PMTCT clinics in studied he previous ... in Western Ethiopia: Cross-sectional Study ... onducted a cross-sectional study from March 01to April.

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ley, 1997). Mechanisms may involve mechanical, barriers to germination embryo may involve the els of certain plant growth regulators, the activity of important respiratory pa or the mobilization and utilization of food reserves et al., 2002). It is well documented that certain and sub-tropical grass species have positive resp.

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Abstract. This study focused on the evaluation of supply variability. Nigeria. The field work of the study involved the use installation of water meters to obtain data on household within the metropolis. The findings of the study revealed water use was 86.22 liters/capita/day which liters/capita/day for developing nations.

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African and Asian Termitomyces samples suggeste incorporating more .... and South-West part of the country (Teferi ..... tylerianus in fruit body dimensions, but it differs in exhibiting .... small size elder people do not prefer it since it takes much.

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Abstract. This study was conducted with the hypothesis that the against the practice of animal euthanasia. Participatory interview were used to gather the required data. There respondents which working equines suffer protracted dea the interviewed equine owners revealed that they had eq the last one year. About 36% of ...

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like Ethiopia, bananas in most markets are ripen traditional techniques. Local methods, such as the fruits in .... 1 is unusable, 3 is unsalable, 5 is fair, 7 is good, and 9 is excellent, was used to evaluate the fruit quality. ... changes in color, firmness and TSS value of bananas. (Dadzie and Orchard, 1997). Ripening period for ...

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Malaysia where it is commonly cultivated and might ha been carried at an early date ... substitute for coffee (Seiyaboh et al., 2013). Red. (based on 100 g dry ... product to local or international markets, pharmaceuticals and beverage industries.

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components and a primary cause of global environmen changes ... cause significant variations in soil prop reduction of .... to selective removal of clay from the surface by erosion. ..... should be given special attention to increase the essential.

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camel market and used in a 120 days fattening study. Th where the camels were ... libitum and a supplement of concentrate mix of ... l of camel hides as a product. Ethiopia .... the Ethiopian Leather and Leather Products Technology. Institute ...

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systems, and constitute an important livestock compon ... ricultural systems in the the human population ..... Farta sheep supplemented with noug seed cake, wheat bran and ..... live stock and livestock characteristics (private peasant holdings).

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DPPH radicals (Kekuda et al., 2015). ABTS Radical Scavenging Assay. The ABTS (2,2-azinobis 3-ethylbenzothiazoline 6- sulfonate) radical was generated by reacting ABTS stock solution (7mM) with potassium persulfate (2.45mM). The reaction mixture was left in the dark for 16 hours at room temperature and the resulting ...

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2013-06-13

Jun 13, 2013 ... Such cases encourage th use of high yielding forage crops like Napier gras ... fodder crop per unit area of land as compared other grass .... wheat bran. All bags were consistently incubated 1 h after the sheep were offered feed and withdrawn after 4, 8, 16, 24, 48, 72 and 96 h of incubation. Immediately after ...

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interactions network by pathway engineering. (Rowinsky, 2003). ... modeling of such molecular, signal proces pathways is very ... stochastic simulation and model checking (Re et al., 2001). ... of enzymes by protein kinases or regulation of.

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selected from parent population and relevant data w questionnaires and ... little loans to street enterprise owners. ... 3327 (Online) esearch .... linkages exist between these small business ... selected as it is expected to hold a large number.

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... and the persons. Official International Journal of Wollega University, Ethiopia .... need of active learning methods in all education levels which is .... This tool was also used to collect qualitative data .... based on numerical value. The analysis ...

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implementation or non- implementation of what they expected to. ..... respectively. Surprisingly, the teachers made non ..... declarative and interrogative sentence patterns. Teachers ... communication if his/her working memory is saturated by.

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The results of the analysis of variance (ANOVA) revealed all of the characters, except ... Thousand seed weight, tiller number per plant, grain yield, mber of kernel per spike ... thatching) for many in the Ethiopian highlands. H ..... the environment component and the contributions of ..... Assessment of stability and character.

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collectors for their versatile habitats, marvelous colorat and sculpture as ... species and diversity of habits in Indian sub ..... Five pla were marked at random in each orchard/farm in all ...... An assessment of common and rare bird species of the.

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Asrat Dagnew* d Behavioral Science, Bahir dar University, P.O. Box: 79, Bahir Dar ... s recommended that, at the school level parent education .... school. On the other hand, the ..... Elementary and Junior High School Students. Journal of.

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building materials; firewood, income generating activities, energy resources; wildlife .... management practices and threats to the wetlands and evaluate the impact of wetland .... macrostachyus, Erythrina brucei, and Cordia africana are under ...

The potential for research-based information in public health: Identifying unrecognised information needs

Directory of Open Access Journals (Sweden)

Forsetlund Louise

2001-01-01

Full Text Available Abstract Objective To explore whether there is a potential for greater use of research-based information in public health practice in a local setting. Secondly, if research-based information is relevant, to explore the extent to which this generates questioning behaviour. Design Qualitative study using focus group discussions, observation and interviews. Setting Public health practices in Norway. Participants 52 public health practitioners. Results In general, the public health practitioners had a positive attitude towards research-based information, but believed that they had few cases requiring this type of information. They did say, however, that there might be a potential for greater use. During five focus groups and six observation days we identified 28 questions/cases where it would have been appropriate to seek out research evidence according to our definition. Three of the public health practitioners identified three of these 28 cases as questions for which research-based information could have been relevant. This gap is interpreted as representing unrecognised information needs. Conclusions There is an unrealised potential in public health practice for more frequent and extensive use of research-based information. The practitioners did not appear to reflect on the need for scientific information when faced with new cases and few questions of this type were generated.

Top IS research on quality of transaction standards: a structured literature review to identify a research gap

NARCIS (Netherlands)

Folmer, E.J.A.; Berends, W.; Oude Luttighuis, P.; Hillegersberg, J. van

2009-01-01

This paper contains the results of a systematic literature review executed to determine the coverage of transaction standards in top information systems (IS) and management journals. Specifically, it aims to identify a research gap with respect to this topic. The top 25 journals are thoroughly

Definition of chronic kidney disease and measurement of kidney function in original research papers: a review of the literature.

Science.gov (United States)

Anderson, Jocelyn; Glynn, Liam G

2011-09-01

Over the past decade, chronic kidney disease (CKD) has become an area of intensive clinical and epidemiological research. Despite the clarity provided by the Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines, there appears to be within the CKD research literature significant disagreement on how to define CKD and measure kidney function. The objectives of this study were to investigate the variety of methods used to define CKD and to measure kidney function in original research papers as well as to investigate whether the quality of the journal had any effect on the quality of the methodology used. This was a descriptive review and not a meta-analysis. Information was extracted from each article including publication details (including the journal's impact factor), definition of CKD, method used to estimate kidney function and quantity of serum creatinine readings used to define CKD. An electronic search of MEDLINE through OVID was completed using the search term CKD. The search was limited to articles in English published in 2009. Studies were included in the review only if they were original research articles including patients with CKD. Articles were excluded if they reported data from a paediatric population, a population solely on dialysis or if there was no full-text access through OVID. Each article was assessed for quality with respect to using KDOQI CKD definition criteria. A description of the pooled data was completed and chi-square tests were used to investigate the relation between article quality and journal quality. Analysis was carried out using SPSS (15.0) and a P-value of definitions are being used in original research articles to define CKD and measure kidney function which calls into question the validity and reliability of such research findings and associated clinical guidelines. International consensus is urgently required to improve validity and generalizability of CKD research findings.

TERMES D’EMPRUNT D’ORIGINE FRANÇAISE DANS LA TERMINOLOGIE ARMENIENNE: ÉTUDE DIACHRONIQUE

Directory of Open Access Journals (Sweden)

Karine DOIMADJIAN-GRIGORYAN

2016-12-01

Full Text Available Les mots d'origine française font une partie indissociable du patrimoine linguistique de la langue arménienne. Nos recherches démontrent que le tiers des mots empruntés au français sont des termes.  Ils figurent dans divers domaines: science et technique, art et littérature, politique et sciences humaines, architecture et construction, industrie et agriculture etc. Dans cette recherche nous nous proposons d’identifier les périodes d’emprunt lexical au français sur le corpus des termes d'origine française afin de montrer le rôle et la place de ces témoins fidèles qui illustrent les relations multiples et diverses que les peuples arménien et français ont entretenues et entretiennent.BORROWED TERMS OF ORIGIN FRENCH IN ARMENIAN TERMINOLOGY: DIACHRONIC STUDY The words of origin French are an inseparable part of the linguistic heritage of the Armenian language. Our research shows that one third of words borrowed from French are terms. They appear in various areas: science and technology, art and literature, politics and human sciences, architecture and construction, industry and agriculture etc. In this research we propose to identify periods of loanword in French on the corpus of words of French origin to show the role and place of these faithful witnesses that illustrate the multiple and diverse relationships as the Armenian and French peoples have maintained and maintain.

Identifying the conditions needed for integrated knowledge translation (IKT) in health care organizations: qualitative interviews with researchers and research users.

Science.gov (United States)

Gagliardi, Anna R; Dobrow, Mark J

2016-07-12

Collaboration among researchers and research users, or integrated knowledge translation (IKT), enhances the relevance and uptake of evidence into policy and practice. However, it is not widely practiced and, even when well-resourced, desired impacts may not be achieved. Given that large-scale investment is not the norm, further research is needed to identify how IKT can be optimized. Interviews were conducted with researchers and research users (clinicians, managers) in a health care delivery (HCDO) and health care monitoring (HCMO) organization that differed in size and infrastructure, and were IKT-naïve. Basic qualitative description was used. Participants were asked about IKT activities and challenges, and recommendations for optimizing IKT. Data were analysed inductively using constant comparative technique. Forty-three interviews were conducted (28 HCDO, 15 HCMO) with 13 researchers, 8 clinicians, and 22 managers. Little to no IKT took place. Participants articulated similar challenges and recommendations revealing that a considerable number of changes were needed at the organizational, professional and individual levels. Given the IKT-absent state of participating organizations, this research identified a core set of conditions which must be addressed to prepare an environment conducive to IKT. These conditions were compiled into a framework by which organizations can plan for, or evaluate their capacity for IKT. The IKT capacity framework is relevant for organizations in which there is no current IKT activity. Use of the IKT framework may result in more organizations that are ready to initiate and establish IKT, perhaps ultimately leading to more, and higher-quality collaboration for health system innovation. Further research is needed to confirm these findings in other organizations not yet resourced for, or undertaking IKT, and to explore the resource implications and mechanisms for establishing the conditions identified here as essential to preparing for

Priority setting partnership to identify the top 10 research priorities for the management of Parkinson's disease.

Science.gov (United States)

Deane, Katherine H O; Flaherty, Helen; Daley, David J; Pascoe, Roland; Penhale, Bridget; Clarke, Carl E; Sackley, Catherine; Storey, Stacey

2014-12-14

This priority setting partnership was commissioned by Parkinson's UK to encourage people with direct and personal experience of the condition to work together to identify and prioritise the top 10 evidential uncertainties that impact on everyday clinical practice for the management of Parkinson's disease (PD). The UK. Anyone with experience of PD including: people with Parkinson's (PwP), carers, family and friends, healthcare and social care professionals. Non-clinical researchers and employees of pharmaceutical or medical devices companies were excluded. 1000 participants (60% PwP) provided ideas on research uncertainties, 475 (72% PwP) initially prioritised them and 27 (37% PwP) stakeholders agreed a final top 10. Using a modified nominal group technique, participants were surveyed to identify what issues for the management of PD needed research. Unique research questions unanswered by current evidence were identified and participants were asked to identify their top 10 research priorities from this list. The top 26 uncertainties were presented to a consensus meeting with key stakeholders to agree the top 10 research priorities. 1000 participants provided 4100 responses, which contained 94 unique unanswered research questions that were initially prioritised by 475 participants. A consensus meeting with 27 stakeholders agreed the top 10 research priorities. The overarching research aspiration was an effective cure for PD. The top 10 research priorities for PD management included the need to address motor symptoms (balance and falls, and fine motor control), non-motor symptoms (sleep and urinary dysfunction), mental health issues (stress and anxiety, dementia and mild cognitive impairments), side effects of medications (dyskinesia) and the need to develop interventions specific to the phenotypes of PD and better monitoring methods. These research priorities identify crucial gaps in the existing evidence to address everyday practicalities in the management of the

Identifying and Prioritizing Information Needs and Research Priorities of Public Health Emergency Preparedness and Response Practitioners.

Science.gov (United States)

Siegfried, Alexa L; Carbone, Eric G; Meit, Michael B; Kennedy, Mallory J; Yusuf, Hussain; Kahn, Emily B

2017-10-01

This study describes findings from an assessment conducted to identify perceived knowledge gaps, information needs, and research priorities among state, territorial, and local public health preparedness directors and coordinators related to public health emergency preparedness and response (PHPR). The goal of the study was to gather information that would be useful for ensuring that future funding for research and evaluation targets areas most critical for advancing public health practice. We implemented a mixed-methods approach to identify and prioritize PHPR research questions. A web survey was sent to all state, city, and territorial health agencies funded through the Public Health Emergency Preparedness (PHEP) Cooperative Agreement program and a sample of local health departments (LHDs). Three focus groups of state and local practitioners and subject matter experts from the Centers for Disease Control and Prevention (CDC) were subsequently conducted, followed by 3 meetings of an expert panel of PHPR practitioners and CDC experts to prioritize and refine the research questions. We identified a final list of 44 research questions that were deemed by study participants as priority topics where future research can inform PHPR programs and practice. We identified differences in perceived research priorities between PHEP awardees and LHD survey respondents; the number of research questions rated as important was greater among LHDs than among PHEP awardees (75%, n=33, compared to 24%, n=15). The research questions identified provide insight into public health practitioners' perceived knowledge gaps and the types of information that would be most useful for informing and advancing PHPR practice. The study also points to a higher level of information need among LHDs than among PHEP awardees. These findings are important for CDC and the PHPR research community to ensure that future research studies are responsive to practitioners' needs and provide the information

Protocol for a thematic synthesis to identify key themes and messages from a palliative care research network.

LENUS (Irish Health Repository)

Nicholson, Emma

2016-10-21

Research networks that facilitate collaborative research are increasing both regionally and globally and such collaborations contribute greatly to knowledge transfer particularly in health research. The Palliative Care Research Network is an Irish-based network that seeks to create opportunities and engender a collaborative environment to encourage innovative research that is relevant for policy and practice. The current review outlines a methodology to identify cross-cutting messages to identify how dissemination outputs can be optimized to ensure that key messages from this research reaches all knowledge users.

The use of citation indicators to identify and support high-quality research in Poland.

Science.gov (United States)

Pilc, Andrzej

2008-01-01

In large, mostly English-speaking countries, where the "critical mass" of scientists working in different subfields of science is achieved, the peer review system may be sufficient to assess the quality of scientific research. However, in smaller countries, outside the Anglo-American circle, it is important to introduce different systems to identify research of high quality. In Poland, a parametric system for assessing the quality of research has been introduced. It was largely based on the impact factor of scientific journals. While the use of this indicator to assess research quality is highly questionable, the implementation of the system in the Polish reality is even worse. Therefore it is important to change and improve the system currently used by the Ministry of Science and Higher Education to both evaluate and, more importantly, finance science in Poland. Here, a system based on three factors, i.e. the impact factor, the institutional h-index, and the institutional number of citations, is proposed. The scientific quality of institutions in Division VI: Medical Sciences of the Polish Academy of Sciences were evaluated and the results were compared with the existing system. Moreover, a method to identify high-quality researchers and institutions at the national level based on the quantity of highly cited papers is shown. Additionally, an attempt to identify the highest quality Polish research on an international level is proposed. This is based on the number of individual citations, the individual h-index, the number of publications, and the priority of the discovery.

Qualitative Research in Counseling Psychology: Conceptual Foundations

Science.gov (United States)

Morrow, Susan L.

2007-01-01

Beginning with calls for methodological diversity in counseling psychology, this article addresses the history and current state of qualitative research in counseling psychology. It identifies the historical and disciplinary origins as well as basic assumptions and underpinnings of qualitative research in general, as well as within counseling…

Critical research needs for identifying future changes in Gulf coral reef ecosystems

KAUST Repository

Feary, David A.

2013-07-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/Persian Gulf (thereafter \\'Gulf\\') coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. © 2013 Elsevier Ltd.

Critical research needs for identifying future changes in Gulf coral reef ecosystems

Science.gov (United States)

Feary, David A.; Burt, John A.; Bauman, Andrew G.; Al Hazeem, Shaker; Abdel-Moati, Mohamed A.; Al-Khalifa, Khalifa A.; Anderson, Donald M.; Amos, Carl; Baker, Andrew; Bartholomew, Aaron; Bento, Rita; Cavalcante, Geórgenes H.; Chen, Chaolun Allen; Coles, Steve L.; Dab, Koosha; Fowler, Ashley M.; George, David; Grandcourt, Edwin; Hill, Ross; John, David M.; Jones, David A.; Keshavmurthy, Shashank; Mahmoud, Huda; Moradi Och Tapeh, Mahdi; Mostafavi, Pargol Ghavam; Naser, Humood; Pichon, Michel; Purkis, Sam; Riegl, Bernhard; Samimi-Namin, Kaveh; Sheppard, Charles; Vajed Samiei, Jahangir; Voolstra, Christian R.; Wiedenmann, Joerg

2014-01-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/ Persian Gulf (thereafter ‘Gulf’) coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. PMID:23643407

Critical research needs for identifying future changes in Gulf coral reef ecosystems

KAUST Repository

Feary, David A.; Burt, John A.; Bauman, Andrew G.; Al Hazeem, Shaker; Abdel-Moati, Mohamed A R; Al-Khalifa, Khalifa A.; Anderson, Donald M.; Amos, Carl L.; Baker, Andrew C.; Bartholomew, Aaron; Bento, Rita; Cavalcante, Geó rgenes H.; Chen, Chaolun Allen; Coles, Steve L.; Dab, Koosha; Fowler, Ashley M.; George, David Glen; Grandcourt, Edwin Mark; Hill, Ross; John, David Michael; Jones, David Alan; Keshavmurthy, Shashank; Mahmoud, Huda M A; Moradi Och Tapeh, Mahdi; Mostafavi, Pargol Ghavam; Naser, Humood A.; Pichon, Michel; Purkis, Sam J.; Riegl, Bernhard M.; Samimi-Namin, Kaveh; Sheppard, Charles R C; Vajed Samiei, Jahangir; Voolstra, Christian R.; Wiedenmann, Jö rg

2013-01-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/Persian Gulf (thereafter 'Gulf') coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. © 2013 Elsevier Ltd.

Diverse origins of Arctic and Subarctic methane point source emissions identified with multiply-substituted isotopologues

Science.gov (United States)

Douglas, P. M. J.; Stolper, D. A.; Smith, D. A.; Walter Anthony, K. M.; Paull, C. K.; Dallimore, S.; Wik, M.; Crill, P. M.; Winterdahl, M.; Eiler, J. M.; Sessions, A. L.

2016-09-01

Methane is a potent greenhouse gas, and there are concerns that its natural emissions from the Arctic could act as a substantial positive feedback to anthropogenic global warming. Determining the sources of methane emissions and the biogeochemical processes controlling them is important for understanding present and future Arctic contributions to atmospheric methane budgets. Here we apply measurements of multiply-substituted isotopologues, or clumped isotopes, of methane as a new tool to identify the origins of ebullitive fluxes in Alaska, Sweden and the Arctic Ocean. When methane forms in isotopic equilibrium, clumped isotope measurements indicate the formation temperature. In some microbial methane, however, non-equilibrium isotope effects, probably related to the kinetics of methanogenesis, lead to low clumped isotope values. We identify four categories of emissions in the studied samples: thermogenic methane, deep subsurface or marine microbial methane formed in isotopic equilibrium, freshwater microbial methane with non-equilibrium clumped isotope values, and mixtures of deep and shallow methane (i.e., combinations of the first three end members). Mixing between deep and shallow methane sources produces a non-linear variation in clumped isotope values with mixing proportion that provides new constraints for the formation environment of the mixing end-members. Analyses of microbial methane emitted from lakes, as well as a methanol-consuming methanogen pure culture, support the hypothesis that non-equilibrium clumped isotope values are controlled, in part, by kinetic isotope effects induced during enzymatic reactions involved in methanogenesis. Our results indicate that these kinetic isotope effects vary widely in microbial methane produced in Arctic lake sediments, with non-equilibrium Δ18 values spanning a range of more than 5‰.

Historical Origins of Information Behavior Research by Reference Publication Year Spectroscopy

Directory of Open Access Journals (Sweden)

Faramarz Soheili

2015-12-01

Full Text Available Background: Using a quantitative method named reference publication year spectroscopy (RPYS, this research tried to determine the historical roots of information behavior research. RPYS pave the way for determining the significant years and works in information behavior. Methodology: Using scientometric method, the initial data of this study, have been extracted from the Web of Science. Using RPYS software, the revised data were analyzed and visualized in Excel. Finding: The distribution of cited references in information behavior revealed three peaks within 19th century. Moreover, our analysis identified 6 peaks between 1900 to 1969 in the field of information behavior, respectively in 1948, 1954, 1957, 1960, 1965, and 1967 has occurred. Results: Based on the study findings, it seems that information behavior research has been shaped intellectually by fields such as Psychology, quantitative and qualitative methodologies, etc. Additionally, it has been influenced by some theories and theoretical works.

Publication of Original Research in Urologic Journals ? A Neglected Orphan?

OpenAIRE

Mani, Jens; Makarevi?, Jasmina; Juengel, Eva; Ackermann, Hanns; Nelson, Karen; Haferkamp, Axel; Blaheta, Roman A.

2012-01-01

The pathophysiologic mechanisms behind urologic disease are increasingly being elucidated. The object of this investigation was to evaluate the publication policies of urologic journals during a period of progressively better understanding and management of urologic disease. Based on the ISI Web of Knowledge Journal Citation Reports and the PubMed database, the number and percentage of original experimental, original clinical, review or commentarial articles published between 2002–2010 in six...

Foreign research reactor irradiated nuclear fuel inventories containing HEU and LEU of United States origin

International Nuclear Information System (INIS)

Matos, J.E.

1994-12-01

This report provides estimates of foreign research reactor inventories of aluminum-based and TRIGA irradiated nuclear fuel elements containing highly enriched and low enriched uranium of United States origin that are anticipated in January 1996, January 2001, and January 2006. These fuels from 104 research reactors in 41 countries are the same aluminum-based and TRIGA fuels that were eligible for receipt under the Department of Energy's Offsite Fuels Policy that was in effect in 1988. All fuel inventory and reactor data that were available as of December 1, 1994, have been included in the estimates of approximately 14,300 irradiated fuel elements in January 1996, 18,800 in January 2001, and 22,700 in January 2006

What is the Value Proposition of Persistent Identifiers?

Science.gov (United States)

Klump, Jens; Huber, Robert

2017-04-01

Persistent identifiers (PID) are widely used today in scientific communication and documentation. Global unique identification plus persistent resolution of links to referenced digital research objects have been strong selling points for PID Systems as enabling technical infrastructures. Novel applications of PID Systems in research now go beyond the identification of file based objects such as literature or data sets and include the identification of dynamically changing datasets accessed through web services, physical objects, persons and organisations. But not only do we see more use cases but also a proliferation of identifier systems. An analysis of PID Systems used by 1381 repositories listed in the Registry of Research Data Repositories (re3data.org, status of 14 Dec 2015) showed that many disciplinary data repositories make use of PID that are not among the systems promoted by the libraries and publishers (DOI, PURL, ARK). This indicates that a number of communities have developed their own PID Systems. This begs the question, do we need more identifier systems? What makes their value proposition more appealing than those of already existing systems? On the other hand, some of these new use cases deal with entities outside the digital domain, the original scope of application for PIDs. It is therefore necessary to critically appraise the value propositions of available PID Systems and compare these against the requirements of new use cases for PID. Undoubtedly, DOI are the most used persistent identifier in scholarly communication. It was originally designed "to link customers with publishers, facilitate electronic commerce, and enable copyright management systems." Today, the DOI system is described as providing "a technical and social infrastructure for the registration and use of persistent interoperable identifiers for use on digital networks". This example shows how value propositions can change over time. Additional value can be gained by cross

Mineral Surface-Templated Self-Assembling Systems: Case Studies from Nanoscience and Surface Science towards Origins of Life Research.

Science.gov (United States)

Gillams, Richard J; Jia, Tony Z

2018-05-08

An increasing body of evidence relates the wide range of benefits mineral surfaces offer for the development of early living systems, including adsorption of small molecules from the aqueous phase, formation of monomeric subunits and their subsequent polymerization, and supramolecular assembly of biopolymers and other biomolecules. Each of these processes was likely a necessary stage in the emergence of life on Earth. Here, we compile evidence that templating and enhancement of prebiotically-relevant self-assembling systems by mineral surfaces offers a route to increased structural, functional, and/or chemical complexity. This increase in complexity could have been achieved by early living systems before the advent of evolvable systems and would not have required the generally energetically unfavorable formation of covalent bonds such as phosphodiester or peptide bonds. In this review we will focus on various case studies of prebiotically-relevant mineral-templated self-assembling systems, including supramolecular assemblies of peptides and nucleic acids, from nanoscience and surface science. These fields contain valuable information that is not yet fully being utilized by the origins of life and astrobiology research communities. Some of the self-assemblies that we present can promote the formation of new mineral surfaces, similar to biomineralization, which can then catalyze more essential prebiotic reactions; this could have resulted in a symbiotic feedback loop by which geology and primitive pre-living systems were closely linked to one another even before life’s origin. We hope that the ideas presented herein will seed some interesting discussions and new collaborations between nanoscience/surface science researchers and origins of life/astrobiology researchers.

Mineral Surface-Templated Self-Assembling Systems: Case Studies from Nanoscience and Surface Science towards Origins of Life Research

Directory of Open Access Journals (Sweden)

Richard J. Gillams

2018-05-01

Full Text Available An increasing body of evidence relates the wide range of benefits mineral surfaces offer for the development of early living systems, including adsorption of small molecules from the aqueous phase, formation of monomeric subunits and their subsequent polymerization, and supramolecular assembly of biopolymers and other biomolecules. Each of these processes was likely a necessary stage in the emergence of life on Earth. Here, we compile evidence that templating and enhancement of prebiotically-relevant self-assembling systems by mineral surfaces offers a route to increased structural, functional, and/or chemical complexity. This increase in complexity could have been achieved by early living systems before the advent of evolvable systems and would not have required the generally energetically unfavorable formation of covalent bonds such as phosphodiester or peptide bonds. In this review we will focus on various case studies of prebiotically-relevant mineral-templated self-assembling systems, including supramolecular assemblies of peptides and nucleic acids, from nanoscience and surface science. These fields contain valuable information that is not yet fully being utilized by the origins of life and astrobiology research communities. Some of the self-assemblies that we present can promote the formation of new mineral surfaces, similar to biomineralization, which can then catalyze more essential prebiotic reactions; this could have resulted in a symbiotic feedback loop by which geology and primitive pre-living systems were closely linked to one another even before life’s origin. We hope that the ideas presented herein will seed some interesting discussions and new collaborations between nanoscience/surface science researchers and origins of life/astrobiology researchers.

Gamma-rays attenuation of zircons from Cambodia and South Africa at different energies: A new technique for identifying the origin of gemstone

International Nuclear Information System (INIS)

Limkitjaroenporn, P.; Kaewkhao, J.

2014-01-01

In this work, the gamma-rays interaction properties of zircons from Cambodia and South Africa have been studied. The densities of Cambodian and South African’s zircons are 4.6716±0.0040 g/cm 3 and 4.5505±0.0018 g/cm 3 , respectively. The mass attenuation coefficient and the effective atomic number of gemstones were measured with the gamma-ray in energies range 223–662 keV using the Compton scattering technique. The mass attenuation coefficients of both zircons decreased with the increasing of gamma-rays energies. The different mass attenuation coefficients between the two zircons observed at gamma-ray energies below 400 keV are attributed to the differences in the photoelectric interaction. The effective atomic number of zircons was decreased with the increasing of gamma-ray energies and showed totally different values between the Cambodia and South Africa sources. The origins of the two zircons could be successfully identified by the method based on gamma-rays interaction with matter with advantage of being a non-destructive testing. - Highlights: • Gamma-rays interaction of zircons from Cambodia and South Africa studied. • Measured energy is during 223–662 keV. • Different μ m between the two zircons observed at gamma-ray energies below 400 keV. • The origins the two zircons could be successfully identified

Progress in the Legitimacy of Business and Management Education Research: Rejoinder to "Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory"

Science.gov (United States)

Bacon, Donald R.

2016-01-01

In this rejoinder to "Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory," published in the "Journal of Management Education," Dec 2016 (see EJ1118407), Donald R. Bacon discusses the similarities between Arbaugh et al.'s (2016) findings and the scholarship…

NHash: Randomized N-Gram Hashing for Distributed Generation of Validatable Unique Study Identifiers in Multicenter Research.

Science.gov (United States)

Zhang, Guo-Qiang; Tao, Shiqiang; Xing, Guangming; Mozes, Jeno; Zonjy, Bilal; Lhatoo, Samden D; Cui, Licong

2015-11-10

A unique study identifier serves as a key for linking research data about a study subject without revealing protected health information in the identifier. While sufficient for single-site and limited-scale studies, the use of common unique study identifiers has several drawbacks for large multicenter studies, where thousands of research participants may be recruited from multiple sites. An important property of study identifiers is error tolerance (or validatable), in that inadvertent editing mistakes during their transmission and use will most likely result in invalid study identifiers. This paper introduces a novel method called "Randomized N-gram Hashing (NHash)," for generating unique study identifiers in a distributed and validatable fashion, in multicenter research. NHash has a unique set of properties: (1) it is a pseudonym serving the purpose of linking research data about a study participant for research purposes; (2) it can be generated automatically in a completely distributed fashion with virtually no risk for identifier collision; (3) it incorporates a set of cryptographic hash functions based on N-grams, with a combination of additional encryption techniques such as a shift cipher; (d) it is validatable (error tolerant) in the sense that inadvertent edit errors will mostly result in invalid identifiers. NHash consists of 2 phases. First, an intermediate string using randomized N-gram hashing is generated. This string consists of a collection of N-gram hashes f1, f2, ..., fk. The input for each function fi has 3 components: a random number r, an integer n, and input data m. The result, fi(r, n, m), is an n-gram of m with a starting position s, which is computed as (r mod |m|), where |m| represents the length of m. The output for Step 1 is the concatenation of the sequence f1(r1, n1, m1), f2(r2, n2, m2), ..., fk(rk, nk, mk). In the second phase, the intermediate string generated in Phase 1 is encrypted using techniques such as shift cipher. The result

Consumer ethnocentrism and Country of origin effect

DEFF Research Database (Denmark)

Iacob, Andrea Ioana

The research on consumer ethnocentrism and country of origin effect is quite substantial in the area of consumer research, but there are competing views as to how low involvement products influence and interact with consumer ethnocentrism and country of origin in a transitional market setting...

75 FR 57768 - Access to Confidential Business Information by Eastern Research Group and Its Identified...

Science.gov (United States)

2010-09-22

... Business Information by Eastern Research Group and Its Identified Subcontractor AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: EPA has authorized its contractor, Eastern Research Group... the information may be claimed or determined to be Confidential Business Information (CBI). DATES...

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.

Directory of Open Access Journals (Sweden)

Clive J Hoggart

2014-07-01

Full Text Available The phenotypic effect of some single nucleotide polymorphisms (SNPs depends on their parental origin. We present a novel approach to detect parent-of-origin effects (POEs in genome-wide genotype data of unrelated individuals. The method exploits increased phenotypic variance in the heterozygous genotype group relative to the homozygous groups. We applied the method to >56,000 unrelated individuals to search for POEs influencing body mass index (BMI. Six lead SNPs were carried forward for replication in five family-based studies (of ∼4,000 trios. Two SNPs replicated: the paternal rs2471083-C allele (located near the imprinted KCNK9 gene and the paternal rs3091869-T allele (located near the SLC2A10 gene increased BMI equally (beta = 0.11 (SD, P<0.0027 compared to the respective maternal alleles. Real-time PCR experiments of lymphoblastoid cell lines from the CEPH families showed that expression of both genes was dependent on parental origin of the SNPs alleles (P<0.01. Our scheme opens new opportunities to exploit GWAS data of unrelated individuals to identify POEs and demonstrates that they play an important role in adult obesity.

Original Research Risk factors for Anopheles mosquitoes in rural ...

African Journals Online (AJOL)

have suggested that the strongest risk factor for malaria. Original ..... mosquitoes are adapted to urban environments characterised .... Reduction of childhood malaria by social marketing of insecticide-treated ... and ICF Macro; 2011. 22.

Assessing elements of an extended evolutionary synthesis for plant domestication and agricultural origin research

Science.gov (United States)

Piperno, Dolores R.

2017-01-01

The development of agricultural societies, one of the most transformative events in human and ecological history, was made possible by plant and animal domestication. Plant domestication began 12,000–10,000 y ago in a number of major world areas, including the New World tropics, Southwest Asia, and China, during a period of profound global environmental perturbations as the Pleistocene epoch ended and transitioned into the Holocene. Domestication is at its heart an evolutionary process, and for many prehistorians evolutionary theory has been foundational in investigating agricultural origins. Similarly, geneticists working largely with modern crops and their living wild progenitors have documented some of the mechanisms that underwrote phenotypic transformations from wild to domesticated species. Ever-improving analytic methods for retrieval of empirical data from archaeological sites, together with advances in genetic, genomic, epigenetic, and experimental research on living crop plants and wild progenitors, suggest that three fields of study currently little applied to plant domestication processes may be necessary to understand these transformations across a range of species important in early prehistoric agriculture. These fields are phenotypic (developmental) plasticity, niche construction theory, and epigenetics with transgenerational epigenetic inheritance. All are central in a controversy about whether an Extended Evolutionary Synthesis is needed to reconceptualize how evolutionary change occurs. An exploration of their present and potential utility in domestication study shows that all three fields have considerable promise in elucidating important issues in plant domestication and in agricultural origin and dispersal research and should be increasingly applied to these issues. PMID:28576881

78 FR 67139 - Access to Confidential Business Information by Eastern Research Group and Its Identified...

Science.gov (United States)

2013-11-08

... Business Information by Eastern Research Group and Its Identified Subcontractor, Energy Services, Inc..., Eastern Research Group (ERG) of Chantilly, VA, and subcontractor Energy Services, Inc., of Tallahassee, FL... Control Act (TSCA). Some of the information may be claimed or determined to be Confidential Business...

Geographic origin of publications in radiological journals as a function of GDP and percentage of GDP spent on research.

Science.gov (United States)

Halpenny, Darragh; Burke, John; McNeill, Graeme; Snow, Aisling; Torreggiani, William C

2010-06-01

The aim of this study was to examine the geographic origin of publications in the highest impacting radiology journals and to examine the link between the percentage of gross domestic product (GDP) spent on research by a country and the output of radiology publications. The five highest impacting general radiology journals (according to the ISI Web of Knowledge database) were selected over a 6-year period from January 2002 to December 2007. Publications were totaled according to the country of the corresponding author. Publications (total and corrected for population size) were assessed according to the GDP of a given country and the percentage of GDP spent on research in that country. Correlation was determined using Spearman's rank. In total, 10,925 papers were identified. The top 10 nations produced 83.9% of the total number of papers. The United States was the most prolific country, with 41.7% of the total. The second-ranked and third-ranked countries were Germany (11.6%) and Japan (6.7%). Corrected for GDP, smaller European countries outperformed larger nations. Switzerland (0.925 publications per billion of GDP), Austria (0.694 publications per billion of GDP), and Belgium (0.648 publications per billion of GDP) produced the most papers per billion of GDP. When corrected for percentage of GDP spent on research, European countries again ranked highest, with Greece, Turkey, and Belgium having the best ratios. The percentage of GDP spent on research was positively correlated with the number of publications in high-ranking radiology journals (r = 0.603, P GDP and the percentage of GDP spent on research may give more meaningful results. When GDP is taken into consideration, smaller European countries are more productive. The importance of investment in radiologic research is emphasized by the association between increased funding of research and the number of publications in high-impacting radiology journals. Copyright (c) 2010 AUR. Published by Elsevier Inc. All

Geographic and Research Center Origins of Rice Resistance to Asian Planthoppers and Leafhoppers: Implications for Rice Breeding and Gene Deployment

Directory of Open Access Journals (Sweden)

Finbarr G. Horgan

2017-09-01

Full Text Available This study examines aspects of virulence to resistant rice varieties among planthoppers and leafhoppers. Using a series of resistant varieties, brown planthopper, Nilaparvata lugens, virulence was assessed in seedlings and early-tillering plants at seven research centers in South and East Asia. Virulence of the whitebacked planthopper, Sogatella furcifera, in Taiwan and the Philippines was also assessed. Phylogenetic analysis of the varieties using single-nucleotide polymorphisms (SNPs indicated a clade of highly resistant varieties from South Asia with two further South Asian clades of moderate resistance. Greenhouse bioassays indicated that planthoppers can develop virulence against multiple resistance genes including genes introgressed from wild rice species. Nilaparvata lugens populations from Punjab (India and the Mekong Delta (Vietnam were highly virulent to a range of key resistance donors irrespective of variety origin. Sogatella furcifera populations were less virulent to donors than N. lugens; however, several genes for resistance to S. furcifera are now ineffective in East Asia. A clade of International Rice Research Institute (IRRI-bred varieties and breeding lines, without identified leafhopper-resistance genes, were highly resistant to the green leafhopper, Nephotettix virescens. Routine phenotyping during breeding programs likely maintains high levels of quantitative resistance to leafhoppers. We discuss these results in the light of breeding and deploying resistant rice in Asia.

40 CFR 52.2087 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan.... (B) Original consent agreement between the Rhode Island Department of Environmental Management and...

40 CFR 52.2921 - Original identification of plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan. 52.2921 Section 52.2921 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Mariana Islands § 52.2921 Original identification of plan. (a) This section identified the original...

Country of origin effect on brand perception

DEFF Research Database (Denmark)

Iacob, Andreea

2016-01-01

During the past two decades there has been a substantial amount of empirical evidence on the country of origin phenomenon. However, marketing scholars have different perspectives and views on how the country of origin effect has impacted the brand perceptions of consumers. This paper presents...... an extensive review of the literature on the COO effect and traces the conceptual development of the country-of-origin construct in order to provide scholars and practitioners with a critical appraisal of the existing research on this topic. By following the grounds of the systematic literature, this study...... seeks to establish a solid base for country-of-origin research review....

Original Research by Young Twinkle Students (ORBYTS): When Can Students Start Performing Original Research?

Science.gov (United States)

Sousa-Silva, Clara; McKemmish, Laura K.; Chubb, Katy L.; Gorman, Marie N.; Baker, Jack S.; Barton, Emma J.; Rivlin, Tom; Tennyson, Jonathan

2018-01-01

Involving students in state-of-the-art research from an early age eliminates the idea that science is only for the scientists and empowers young people to explore STEM (Science, Technology, Engineering and Maths) subjects. It is also a great opportunity to dispel harmful stereotypes about who is suitable for STEM careers, while leaving students…

40 CFR 52.2635 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan... implementation plan (SIP) for Sheridan, Wyoming. In addition to the original August 28 submittal, eight...

40 CFR 52.2134 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... Original identification of plan section. (a) This section identifies the original “South Carolina Air... Charleston; for these two sources, the plan's original emission limits continue to apply.) (10) Permit...

40 CFR 52.2823 - Original identification of plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) American Samoa § 52.2823 Original identification of plan. (a) This section identified the original “Implementation Plan for Compliance With the...

40 CFR 52.2673 - Original identification of plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Guam § 52.2673 Original identification of plan. (a) This section identified the original “Implementation Plan for Compliance With the...

A note on the possible origin of comets in an interstellar gas cloud

International Nuclear Information System (INIS)

Yabushita, S.; Hasegawa, I.

1978-01-01

A possible origin of comets in an interstellar gas cloud is discussed in relation to the two recent results on cometary research. First, among 200 long-period comets whose original incoming orbits were recently calculated, seven have definitely and 14 have probably negative values of 1/a, where 1/a is twice the binding energy (positive a corresponds to an elliptic orbit) with respect to the solar system barycentre. Second, it has been shown how an aggregate of dust grains embedded in an icy matrix of gaseous compounds could form in an interstellar gas cloud, which could be identified with the icy nucleus of a comet. Again, of about 20 comets whose original 1/a values are negative, seven are transformed into future elliptic orbits by planetary perturbation. Thus, a comet which originated in an interstellar cloud could be captured by the solar system

Conspiracy beliefs and knowledge about HIV origins among adolescents in Soweto, South Africa.

Science.gov (United States)

Hogg, Robert; Nkala, Busisiwe; Dietrich, Janan; Collins, Alexandra; Closson, Kalysha; Cui, Zishan; Kanters, Steve; Chia, Jason; Barhafuma, Bernard; Palmer, Alexis; Kaida, Angela; Gray, Glenda; Miller, Cari

2017-01-01

We examined adolescents' knowledge regarding the origin of HIV/AIDS and correlates of beliefs surrounding conspiracy theories in Soweto, South Africa. Now, a decade post-AIDS denialism, South Africa has the largest antiretroviral therapy roll-out worldwide. However, conspiracy theories stemming from past AIDS denialism may impact HIV prevention and treatment efforts. Study participants were recruited through the Kganya Motsha Adolescent Health Centre and the Perinatal HIV Research Unit's Botsha Bophelo Adolescent Health Study (BBAHS). Adolescents were eligible to participate if aged 14-19 years and living in Soweto. We calculated the proportion of adolescents who correctly believed that HIV originated from non-human primates, and used contingency table analysis and logistic regression modeling to describe correlates associated with accurate knowledge and beliefs in conspiracy theories. Of 830 adolescents, 168 (20.2%) participants correctly identified HIV as originating from chimpanzees and one third (n = 71, 8.6%) believed in a conspiracy theory about the origins of HIV, including that it originated from the US government (2.3%), the pharmaceutical industry (2.2%), a vaccine (2.1%), space (1.5%), and a scientist (0.6%). Participants who were more likely to correctly identify the origin of HIV were older, men, and unemployed. Participants who were men, unemployed or students, and who had a parent or close relative who had died of HIV, were more likely to believe in a conspiracy theory regarding the origins of HIV. Adolescents living in Soweto did not have high levels of accurate knowledge regarding the origins of HIV/AIDS and conspiracy beliefs were present among a small minority of participants. Accurate knowledge of the origins of HIV and debunking myths are important for improving uptake of HIV prevention tools in this population.

Conspiracy beliefs and knowledge about HIV origins among adolescents in Soweto, South Africa.

Directory of Open Access Journals (Sweden)

Robert Hogg

Full Text Available We examined adolescents' knowledge regarding the origin of HIV/AIDS and correlates of beliefs surrounding conspiracy theories in Soweto, South Africa. Now, a decade post-AIDS denialism, South Africa has the largest antiretroviral therapy roll-out worldwide. However, conspiracy theories stemming from past AIDS denialism may impact HIV prevention and treatment efforts.Study participants were recruited through the Kganya Motsha Adolescent Health Centre and the Perinatal HIV Research Unit's Botsha Bophelo Adolescent Health Study (BBAHS. Adolescents were eligible to participate if aged 14-19 years and living in Soweto. We calculated the proportion of adolescents who correctly believed that HIV originated from non-human primates, and used contingency table analysis and logistic regression modeling to describe correlates associated with accurate knowledge and beliefs in conspiracy theories.Of 830 adolescents, 168 (20.2% participants correctly identified HIV as originating from chimpanzees and one third (n = 71, 8.6% believed in a conspiracy theory about the origins of HIV, including that it originated from the US government (2.3%, the pharmaceutical industry (2.2%, a vaccine (2.1%, space (1.5%, and a scientist (0.6%. Participants who were more likely to correctly identify the origin of HIV were older, men, and unemployed. Participants who were men, unemployed or students, and who had a parent or close relative who had died of HIV, were more likely to believe in a conspiracy theory regarding the origins of HIV.Adolescents living in Soweto did not have high levels of accurate knowledge regarding the origins of HIV/AIDS and conspiracy beliefs were present among a small minority of participants. Accurate knowledge of the origins of HIV and debunking myths are important for improving uptake of HIV prevention tools in this population.

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

DEFF Research Database (Denmark)

Blein, Sophie; Bardel, Claire; Danjean, Vincent

2015-01-01

of Investigators of Modifiers of BRCA1/2 for 129 mitochondrial polymorphisms using the iCOGS array. Haplogroup inference and association detection were performed using a phylogenetic approach. ALTree was applied to explore the reference mitochondrial evolutionary tree and detect subclades enriched in affected......, H and T clades), the T1a1 haplogroup has a HR of 0.62 (95% CI, 0.40 to 0.95; P = 0.03). We also identified three potential susceptibility loci, including G13708A/rs28359178, which has demonstrated an inverse association with familial breast cancer risk. CONCLUSIONS: This study illustrates how...... original approaches such as the phylogeny-based method we used can empower classical molecular epidemiological studies aimed at identifying association or risk modification effects....

40 CFR 52.2565 - Original identification of plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) West Virginia § 52.2565 Original identification of plan. (a) This section identifies the original “Air Implementation Plan for the State of West...

40 CFR 52.622 - Original identification of plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan. 52.622... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Hawaii § 52.622 Original identification of plan. (a) This section identified the original “State of Hawaii Air Pollution Control Implementation Plan...

Initiation preference at a yeast origin of replication.

Science.gov (United States)

Brewer, B J; Fangman, W L

1994-04-12

Replication origins in the yeast Saccharomyces cerevisiae are identified as autonomous replication sequence (ARS) elements. To examine the effect of origin density on replication initiation, we have analyzed the replication of a plasmid that contains two copies of the same origin, ARS1. The activation of origins and the direction that replication forks move through flanking sequences can be physically determined by analyzing replication intermediates on two-dimensional agarose gels. We find that only one of the two identical ARSs on the plasmid initiates replication on any given plasmid molecule; that is, this close spacing of ARSs results in an apparent interference between the potential origins. Moreover, in the particular plasmid that we constructed, one of the two identical copies of ARS1 is used four times more frequently than the other one. These results show that the plasmid context is critical for determining the preferred origin. This origin preference is also exhibited when the tandem copies of ARS1 are introduced into a yeast chromosome. The sequences responsible for establishing the origin preference have been identified by deletion analysis and are found to reside in a portion of the yeast URA3 gene.

Identifying future directions for subsurface hydrocarbon migration research

Science.gov (United States)

Leifer, I.; Clark, J. F.; Luyendyk, B.; Valentine, D.

Subsurface hydrocarbon migration is important for understanding the input and impacts of natural hydrocarbon seepage on the environment. Great uncertainties remain in most aspects of hydrocarbon migration, including some basic mechanisms of this four-phase flow of tar, oil, water, and gas through the complex fracture-network geometry particularly since the phases span a wide range of properties. Academic, government, and industry representatives recently attended a workshop to identify the areas of greatest need for future research in shallow hydrocarbon migration.Novel approaches such as studying temporal and spatial seepage variations and analogous geofluid systems (e.g., geysers and trickle beds) allow deductions of subsurface processes and structures that remain largely unclear. Unique complexities exist in hydrocarbon migration due to its multiphase flow and complex geometry, including in-situ biological weathering. Furthermore, many aspects of the role of hydrocarbons (positive and negative) in the environment are poorly understood, including how they enter the food chain (respiration, consumption, etc.) and “percolate” to higher trophic levels. But understanding these ecological impacts requires knowledge of the emissions' temporal and spatial variability and trajectories.

Geographic origin of publications in radiological journals as a function of GDP and percentage of GDP spent on research.

LENUS (Irish Health Repository)

Halpenny, Darragh

2010-06-01

The aim of this study was to examine the geographic origin of publications in the highest impacting radiology journals and to examine the link between the percentage of gross domestic product (GDP) spent on research by a country and the output of radiology publications.

Open access publishing: A review of publications originating from a medical college in Nigeria

Directory of Open Access Journals (Sweden)

Wasiu Lanre Adeyemo

2014-01-01

Full Text Available Background: Open Access (OA publishing has gained tremendous acceptance in academic publishing over the last decade. This paper reviews the number and trend of OA publishing of research papers originating from College of Medicine University of Lagos (CMUL, Nigeria. Materials and Methods: A computerized literature search of PubMed for all published articles originating from CMUL between 1976 and 2013 was conducted. The search phrase used was "College of Medicine University of Lagos". The search was conducted on March 30, 2013. All articles tagged "Free article" or "Free PubMed article" were selected. Results: A total of 1255 articles appeared in PubMed between 1976 and 2013 (37 years. At the first level of screening, 162 articles were identified as "Open Access". Second level of screening to eliminate articles not originating from CMUL identified 124 articles. Only 15 OA articles were published between 1976 and 2000 (24 years, 11 articles appeared as "Open Access" journals between 2001 and 2005 (5 years, 44 between 2006 and 2010 (5 years, and 54 articles were published between 2011 and 2013. Twenty-four of these articles were published in Nigerian OA Journals, and the remaining articles (100 in foreign journals. Conclusions: OA publishing is becoming popular among researchers at CMUL. This trend has been observed worldwide. Nigerian researchers are advised that while going along with the worldwide trend, they should however, be aware of predatory OA journals and publishers. The criteria for determining predatory OA publishers can be accessed via: www.scholarlyoa.com/publishers.

40 CFR 52.1960 - Original Identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original Identification of plan section... Original Identification of plan section. (a) This section identifies the original “State of Oklahoma Air... § 856.1(C) of the Oklahoma statutes to mean “original equipment manufacturer (OEM) or equivalent”. (40...

40 CFR 52.1837 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...) Explanation of why sources could not comply by the original attainment date submitted April 23, 1975, by the...

Identifying and Investigating Difficult Concepts in Engineering Mechanics and Electric Circuits. Research Brief

Science.gov (United States)

Streveler, Ruth; Geist, Monica; Ammerman, Ravel; Sulzbach, Candace; Miller, Ronald; Olds, Barbara; Nelson, Mary

2007-01-01

This study extends ongoing work to identify difficult concepts in thermal and transport science and measure students' understanding of those concepts via a concept inventory. Two research questions provided the focal point: "What important concepts in electric circuits and engineering mechanics do students find difficult to learn?" and…

Sierra Leone Journal of Biomedical Research 28 Original Article

African Journals Online (AJOL)

9 No. 2 http://www.sljbr.org/index.php. 28. Original Article. INHERITANCE ... single group) were tabulated and their possible combination outcome (by crosses) in their ... fashion (dominant-recessive) rather, lip prints exhibit polygenic inheritance ... Keywords: Inheritance pattern, Mendelian fashion, Polygenetic, Incomplete ...

Origins, transformations and key foci in instrumental genesis

DEFF Research Database (Denmark)

Tamborg, Andreas Lindenskov

This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what the...... and instrumental orchestrations have potential shortcomings since the technologies that currently exist in school contexts are rather different from the technologies instrumental genesis was originally developed to study.......This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what...

Revealing Originality of Song Works: An Analysis to the Copyright Law

Directory of Open Access Journals (Sweden)

Derezka Gunti Larasati

2014-12-01

Full Text Available The topic of this paper is to describe the defining criteria of originality of song works. The aspect of originality is important to make such work be protected by Copyright Law. In this research, the criteria to define originality are based on certain doctrines and/or theories of originality that may vary case by case. The use of such doctrines and/or theories are necessary, since the stipulations regarding originality in the Indonesian Copyright Act has not been considered suffice. With regard to the song works, the criteria of originality may be different from other works. Therefore, a comprehensive research on the characteristics of song as a work is also important. This research is a qualitative research with prescriptive design. The research depicts the use of certain doctrines and/or theories as supplementary provisions to the Copyright Law in defining the originality of songs, which have specific characteristics resulted from their author’s creations and intellectuals.

Interdisciplinary research framework for identifying research needs. Case: bioenergy-biodiversity interlinkages

Energy Technology Data Exchange (ETDEWEB)

Furman, E.; Peltola, T.; Varjopuro, R. (eds.)

2009-05-15

A loss of biological diversity continues in spite of the existing, and in some respects, rather elaborate and heavy attempts at management and protection. It has been argued that one of the reasons for the lack of success is the unmet and challenging knowledge needs. Meeting the needs requires integration of various sciences and expertise, since attempts to manage biodiversity gives rise also to many emerging, complex and political questions. Integration of the disciplines needs practices that are able to overcome practical, institutional and cultural obstacles. ALTER-Net, a European network for research on biological diversity under the 6th framework programme, has aimed to undertake further interdisciplinary research that will feed into the addressing of societal needs. This report describes how the integration of research progressed and succeeded during the five year life span of ALTER-Net. Initially the integration between disciplines was given as an overall goal, which did result in determining concrete practices of integration between the sciences, teams and partner organisations. The analysis shows that in spite of complications an interdisciplinary research approach can evolve in large research networks, but this can happen also through unanticipated channels. A large network allows room for several parallel processes of integration. The report depicts the development of and choices leading to the development of an interdisciplinary research framework for ALTER-Net, the IDR framework. The framework presents a method to enhance interdisciplinary syntheses of emerging policy-relevant issues and to further develop the identification of relevant topics as interdisciplinary research projects. The IDR framework was tested by focusing on the interlinkages between the bioenergy question and biodiversity. The report consists of a synthesis of pressing research needs pertaining to that topic. The report presents how the IDR framework was constructed using a method

40 CFR 52.1190 - Original Identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original Identification of plan section... Original Identification of plan section. (a) This section identifies the original “Air Implementation Plan... Stipulation for Entry of Consent Order and Final Order, No. 8-1982. The original Consent Order No. 8-1982 was...

Opportunities for Suborbital Space and Atmospheric Research Facilities on Blue Origin's New Shepard Crew Capsule

Science.gov (United States)

Wagner, E.; DeForest, C. E.

2016-12-01

With the emergence of the commercial space industry, researchers now have more options than ever for conducting research aboard space-going platforms. Blue Origin's New Shepard spacecraft offers a large-format crew capsule, capable of carrying a wide range of high-altitude and microgravity payloads above the Karman Line (100 km). With high flight rates and short approval timelines, investigators are able to use data from one flight to refine research objectives and quickly fly again, closing the loop on the scientific method and rapidly advancing technology development. Young investigators have ready access to real-world experiences in building flight hardware, and more involved missions are using this low-barrier environment to raise Technology Readiness Level of components or subsystems. This talk will introduce the standard interfaces and operations for payloads already flying within the New Shepard capsule. We will also explore opportunities for custom facilities that would allow researchers access to the space environment at altitudes between 60 and 100 km. We will discuss the unique science that can be conducted in this region, above where balloons can dwell, but below satellite orbits, including investigations in heliophysics, planetary science, and aeronomy.

How do authors of systematic reviews deal with research malpractice and misconduct in original studies? A cross-sectional analysis of systematic reviews and survey of their authors.

Science.gov (United States)

Elia, Nadia; von Elm, Erik; Chatagner, Alexandra; Pöpping, Daniel M; Tramèr, Martin R

2016-03-02

To study whether systematic reviewers apply procedures to counter-balance some common forms of research malpractice such as not publishing completed research, duplicate publications, or selective reporting of outcomes, and to see whether they identify and report misconduct. Cross-sectional analysis of systematic reviews and survey of their authors. 118 systematic reviews published in four journals (Ann Int Med, BMJ, JAMA, Lancet), and the Cochrane Library, in 2013. Number (%) of reviews that applied procedures to reduce the impact of: (1) publication bias (through searching of unpublished trials), (2) selective outcome reporting (by contacting the authors of the original studies), (3) duplicate publications, (4) sponsors' and (5) authors' conflicts of interest, on the conclusions of the review, and (6) looked for ethical approval of the studies. Number (%) of reviewers who suspected misconduct are reported. The procedures applied were compared across journals. 80 (68%) reviewers confirmed their data. 59 (50%) reviews applied three or more procedures; 11 (9%) applied none. Unpublished trials were searched in 79 (66%) reviews. Authors of original studies were contacted in 73 (62%). Duplicate publications were searched in 81 (69%). 27 reviews (23%) reported sponsors of the included studies; 6 (5%) analysed their impact on the conclusions of the review. Five reviews (4%) looked at conflicts of interest of study authors; none of them analysed their impact. Three reviews (2.5%) looked at ethical approval of the studies. Seven reviews (6%) suspected misconduct; only 2 (2%) reported it explicitly. Procedures applied differed across the journals. Only half of the systematic reviews applied three or more of the six procedures examined. Sponsors, conflicts of interest of authors and ethical approval remain overlooked. Research misconduct is sometimes identified, but rarely reported. Guidance on when, and how, to report suspected misconduct is needed. Published by the BMJ

Identifying Effective Methods of Instruction for Adult Emergent Readers through Community-Based Research

Science.gov (United States)

Blackmer, Rachel; Hayes-Harb, Rachel

2016-01-01

We present a community-based research project aimed at identifying effective methods and materials for teaching English literacy skills to adult English as a second language emergent readers. We conducted a quasi-experimental study whereby we evaluated the efficacy of two approaches, one based on current practices at the English Skills Learning…

Recent advances in the genome-wide study of DNA replication origins in yeast

Directory of Open Access Journals (Sweden)

Chong ePeng

2015-02-01

Full Text Available DNA replication, one of the central events in the cell cycle, is the basis of biological inheritance. In order to be duplicated, a DNA double helix must be opened at defined sites, which are called DNA replication origins (ORIs. Unlike in bacteria, where replication initiates from a single replication origin, multiple origins are utilized in the eukaryotic genome. Among them, the ORIs in budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe have been best characterized. In recent years, advances in DNA microarray and next-generation sequencing technologies have increased the number of yeast species involved in ORIs research dramatically. The ORIs in some nonconventional yeast species such as Kluyveromyces lactis and Pichia pastoris have also been genome-widely identified. Relevant databases of replication origins in yeast were constructed, then the comparative genomic analysis can be carried out. Here, we review several experimental approaches that have been used to map replication origins in yeast and some of the available web resources related to yeast ORIs. We also discuss the sequence characteristics and chromosome structures of ORIs in the four yeast species, which can be utilized to improve the replication origins prediction.

Recent advances in the genome-wide study of DNA replication origins in yeast

Science.gov (United States)

Peng, Chong; Luo, Hao; Zhang, Xi; Gao, Feng

2015-01-01

DNA replication, one of the central events in the cell cycle, is the basis of biological inheritance. In order to be duplicated, a DNA double helix must be opened at defined sites, which are called DNA replication origins (ORIs). Unlike in bacteria, where replication initiates from a single replication origin, multiple origins are utilized in the eukaryotic genomes. Among them, the ORIs in budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe have been best characterized. In recent years, advances in DNA microarray and next-generation sequencing technologies have increased the number of yeast species involved in ORIs research dramatically. The ORIs in some non-conventional yeast species such as Kluyveromyces lactis and Pichia pastoris have also been genome-widely identified. Relevant databases of replication origins in yeast were constructed, then the comparative genomic analysis can be carried out. Here, we review several experimental approaches that have been used to map replication origins in yeast and some of the available web resources related to yeast ORIs. We also discuss the sequence characteristics and chromosome structures of ORIs in the four yeast species, which can be utilized to improve yeast replication origins prediction. PMID:25745419

Human Trafficking in Ethiopia: A Scoping Review to Identify Gaps in Service Delivery, Research, and Policy.

Science.gov (United States)

Beck, Dana C; Choi, Kristen R; Munro-Kramer, Michelle L; Lori, Jody R

2017-12-01

The purpose of this review is to integrate evidence on human trafficking in Ethiopia and identify gaps and recommendations for service delivery, research and training, and policy. A scoping literature review approach was used to systematically search nursing, medical, psychological, law, and international databases and synthesize information on a complex, understudied topic. The search yielded 826 articles, and 39 met the predetermined criteria for inclusion in the review. Trafficking in Ethiopia has occurred internally and externally in the form of adult and child labor and sex trafficking. There were also some reports of organ trafficking and other closely related human rights violations, such as child marriage, child soldiering, and exploitative intercountry adoption. Risk factors for trafficking included push factors (poverty, political instability, economic problems, and gender discrimination) and pull factors (demand for cheap labor). Trafficking was associated with poor health and economic outcomes for victims. Key recommendations for service delivery, research and training, and policy are identified, including establishing comprehensive services for survivor rehabilitation and reintegration, conducting quantitative health outcomes research, and reforming policy around migration and trafficking. Implementing the recommendations identified by this review will allow policy makers, researchers, and practitioners to take meaningful steps toward confronting human trafficking in Ethiopia.

Evolutionary origins of Brassicaceae specific genes in Arabidopsis thaliana

Science.gov (United States)

2011-01-01

Background All sequenced genomes contain a proportion of lineage-specific genes, which exhibit no sequence similarity to any genes outside the lineage. Despite their prevalence, the origins and functions of most lineage-specific genes remain largely unknown. As more genomes are sequenced opportunities for understanding evolutionary origins and functions of lineage-specific genes are increasing. Results This study provides a comprehensive analysis of the origins of lineage-specific genes (LSGs) in Arabidopsis thaliana that are restricted to the Brassicaceae family. In this study, lineage-specific genes within the nuclear (1761 genes) and mitochondrial (28 genes) genomes are identified. The evolutionary origins of two thirds of the lineage-specific genes within the Arabidopsis thaliana genome are also identified. Almost a quarter of lineage-specific genes originate from non-lineage-specific paralogs, while the origins of ~10% of lineage-specific genes are partly derived from DNA exapted from transposable elements (twice the proportion observed for non-lineage-specific genes). Lineage-specific genes are also enriched in genes that have overlapping CDS, which is consistent with such novel genes arising from overprinting. Over half of the subset of the 958 lineage-specific genes found only in Arabidopsis thaliana have alignments to intergenic regions in Arabidopsis lyrata, consistent with either de novo origination or differential gene loss and retention, with both evolutionary scenarios explaining the lineage-specific status of these genes. A smaller number of lineage-specific genes with an incomplete open reading frame across different Arabidopsis thaliana accessions are further identified as accession-specific genes, most likely of recent origin in Arabidopsis thaliana. Putative de novo origination for two of the Arabidopsis thaliana-only genes is identified via additional sequencing across accessions of Arabidopsis thaliana and closely related sister species

Exploring the dimensionality of the Originality subscale of the Kirton Adaption-Innovation Inventory.

Science.gov (United States)

Im, Subin; Hu, Michael Y; Toh, Rex S

2003-12-01

The Kirton Adaption-Innovation Inventory, which is a widely used measure of innovative (as opposed to adaptive) cognitive individual style, is believed to have three dimensions: Sufficiency of Originality, Efficiency, and Rule/Group Conformity. Several studies have raised concerns regarding its construct validity, specifically with respect to the Sufficiency of Originality subscale. Within this subscale, exploratory factor analysis identified two distinct subdimensions, Idea Generation and Preference for Change. In this study, we used a sample of 356 household participants (with an average age of 56 yr., average income of 39,700 dollars, and average of 15 yr. of education) from the Arkansas Household Research Panel. We then employed Bollen and Grandjean's approach based on confirmatory factor analysis to assess whether there are actually two distinct subdimensions instead of one. Our study shows that within the Sufficiency of Originality subscale, there are indeed two distinct subdimensions, Idea Generation and Preference for Change. Further analyses indicate that dropping double-loaded items identified through exploratory factor analysis significantly improves the fit statistics. Also, allowing correlated errors for the measurement items that belong to the same subdimension can also significantly improve the overall fit of the model based on chi-square statistics.

40 CFR 52.2465 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.2465 Section 52.2465 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.2186 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.2186 Section 52.2186 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.1100 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1100 Section 52.1100 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.1281 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1281 Section 52.1281 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.1426 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1426 Section 52.1426 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Nebraska Air Quality...

40 CFR 52.1535 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1535 Section 52.1535 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.1783 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1783 Section 52.1783 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “Air Implementation Plan...

40 CFR 52.2239 - Original Identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original Identification of plan section. 52.2239 Section 52.2239 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original Identification of plan section. (a) This section identifies the original “Tennessee Air Pollution...

Survived so what? Identifying priorities for research with children and families post-paediatric intensive care unit.

Science.gov (United States)

Manning, Joseph C; Hemingway, Pippa; Redsell, Sarah A

2018-03-01

The involvement of patients and the public in the development, implementation and evaluation of health care services and research is recognized to have tangible benefits in relation to effectiveness and credibility. However, despite >96% of children and young people surviving critical illness or injury, there is a paucity of published reports demonstrating their contribution to informing the priorities for aftercare services and outcomes research. We aimed to identify the service and research priorities for Paediatric Intensive Care Unit survivors with children and young people, their families and other stakeholders. We conducted a face-to-face, multiple-stakeholder consultation event, held in the Midlands (UK), to provide opportunities for experiences, views and priorities to be elicited. Data were gathered using write/draw and tell and focus group approaches. An inductive content analytical approach was used to categorize and conceptualize feedback. A total of 26 individuals attended the consultation exercise, including children and young people who were critical care survivors; their siblings; parents and carers; health professionals; academics; commissioners; and service managers. Consultation findings indicated that future services, interventions and research must be holistic and family-centred. Children and young people advisors reported priorities that focused on longer-term outcomes, whereas adult advisors identified priorities that mapped against the pathways of care. Specific priorities included developing and testing interventions that address unmet communication and information needs. Furthermore, initiatives to optimize the lives and longer-term functional and psycho-social outcomes of Paediatric Intensive Care Unit survivors were identified. This consultation exercise provides further evidence of the value of meaningful patient and public involvement in identifying the priorities for research and services for Paediatric Intensive Care Unit survivors

Mapping yeast origins of replication via single-stranded DNA detection.

Science.gov (United States)

Feng, Wenyi; Raghuraman, M K; Brewer, Bonita J

2007-02-01

Studies in th Saccharomyces cerevisiae have provided a framework for understanding how eukaryotic cells replicate their chromosomal DNA to ensure faithful transmission of genetic information to their daughter cells. In particular, S. cerevisiae is the first eukaryote to have its origins of replication mapped on a genomic scale, by three independent groups using three different microarray-based approaches. Here we describe a new technique of origin mapping via detection of single-stranded DNA in yeast. This method not only identified the majority of previously discovered origins, but also detected new ones. We have also shown that this technique can identify origins in Schizosaccharomyces pombe, illustrating the utility of this method for origin mapping in other eukaryotes.

Causes and prevention of in-stent restenosis of vertebral artery origin after stenting

International Nuclear Information System (INIS)

Zhao Huipin; Li Shenmao; Zhang Guangping

2010-01-01

Vertebral artery stenosis is an important cause of posterior circulation stroke. Vertebral artery stenosis most commonly occurs at its origin site. In recent years, balloon angioplasty and stent implantation have been widely employed in the treatment of vertebral artery origin stenosis. However, the long term outcome of stent implantation is affected by in-stent restenosis. Multiple contributory factors have been identified, but clear understanding of the overall underlying mechanism remains an enigma. With the development of pathophysiology, prevention and treatment methods of in-stent restenosis have been improved. In recent years, drug-eluting stents, radioactive stents and magnetic stents have been widely applied. To some extent, these stents and drug therapy can solve the problem of restenosis. This article aims to review the clinical application and the up-to-date research progresses in preventing and managing vertebral artery origin restenosis. (authors)

COUNTRY-OF-ORIGIN EFFECTS ON PURCHASING DOMESTIC PRODUCTS: THE CASE OF ROMANIA

Directory of Open Access Journals (Sweden)

Roxana-Denisa STOENESCU

2015-06-01

Full Text Available Previous studies revealed that ethnocentric consumers are more willing to purchase a domestic product. Furthermore, country-of-origin has a direct impact on consumers’ decision to buy a product in such a manner that a positive country image can substitute other missing qualities of the product. On the other hand, a strong brand is not expected to compensate for a negative country-of-origin perception. Many brands rely on their home country as a warranty for quality and prestige, in order to gain consumers’ interest and attention. This paper examines the moderating role of variables such as perceived quality, ethnocentrism and familiarity in determining a consumer to buy a domestic product. Through exploratory research, this study aims to investigate to what extent Romania, as country-of-origin for its local products, influences consumers’ decision making process. The major contributions of the study consist of identifying the elements that play a role in consumers’ product evaluation based on the country-of-origin and to improve the understanding of country image effects on the buying intention.

20 Years of persistent identifiers - Which systems are here to stay?

Science.gov (United States)

Klump, Jens; Huber, Robert; Lehnert, Kerstin

2016-04-01

Web-based persistent identifiers have been around for more than 20 years, a period long enough to start observing patterns of success and failure. Persistent identifiers were invented to address challenges arising from the distributed and disorganised nature of the internet, which not only allowed new technologies to emerge, it also made it difficult to maintain a persistent record of science. Persistent identifiers now allow unambiguous identification of resources on the net. The expectations were that persistent identifiers would lead to greater accessibility, transparency and reproducibility of research results. Over the past two decades a number of persistent identifier systems have been built, one of them being Digital Object Identifiers (DOI). While DOI were originally invented by the publishing industry, they quickly became an established way for the identification of research resources. At first, these resources referred to scholarly literature and related resources. Other identifier systems, some of them using DOI as an example, were developed as grass-roots efforts by the scientific community. The concept of using persistent identifiers has since been expanded to other, non-textual resources, like datasets (DOI, EPIC) and geological specimens (IGSN), and more recently to authors and contributors of scholarly works (ORCID), and to software and instruments. A common witticism states that "a great thing about standards is that there are so many to choose from." Setting up identifier systems is technically trivial. The real challenge lies in creating a governance system for the respective identifiers. Which systems will stand the test of time? Drawing on data from the Registry of Research Data Repositories (re3data.org) and our own experience in the field, this presentation looks at the history and adoption of existing identifier systems and how this gives us some indications towards factors influencing sustainability of these systems.

Photochirogenesis: Photochemical Models on the Origin of Biomolecular Homochirality

Directory of Open Access Journals (Sweden)

Cornelia Meinert

2010-05-01

Full Text Available Current research focuses on a better understanding of the origin of biomolecular asymmetry by the identification and detection of the possibly first chiral molecules that were involved in the appearance and evolution of life on Earth. We have reasons to assume that these molecules were specific chiral amino acids. Chiral amino acids have been identified in both chondritic meteorites and simulated interstellar ices. Present research reasons that circularly polarized electromagnetic radiation was identified in interstellar environments and an asymmetric interstellar photon-molecule interaction might have triggered biomolecular symmetry breaking. We review on the possible prebiotic interaction of ‘chiral photons’ in the form of circularly polarized light, with early chiral organic molecules. We will highlight recent studies on enantioselective photolysis of racemic amino acids by circularly polarized light and experiments on the asymmetric photochemical synthesis of amino acids from only one C and one N containing molecules by simulating interstellar environments. Both approaches are based on circular dichroic transitions of amino acids that will be presented as well.

Identifying primary care patient safety research priorities in the UK: a James Lind Alliance Priority Setting Partnership.

Science.gov (United States)

Morris, Rebecca Lauren; Stocks, Susan Jill; Alam, Rahul; Taylor, Sian; Rolfe, Carly; Glover, Steven William; Whitcombe, Joanne; Campbell, Stephen M

2018-02-28

To identify the top 10 unanswered research questions for primary care patient safety research. A modified nominal group technique. UK. Anyone with experience of primary care including: patients, carers and healthcare professionals. 341 patients and 86 healthcare professionals submitted questions. A top 10, and top 30, future research questions for primary care patient safety. 443 research questions were submitted by 341 patients and 86 healthcare professionals, through a national survey. After checking for relevance and rephrasing, a total of 173 questions were collated into themes. The themes were largely focused on communication, team and system working, interfaces across primary and secondary care, medication, self-management support and technology. The questions were then prioritised through a national survey, the top 30 questions were taken forward to the final prioritisation workshop. The top 10 research questions focused on the most vulnerable in society, holistic whole-person care, safer communication and coordination between care providers, work intensity, continuity of care, suicide risk, complex care at home and confidentiality. This study was the first national prioritisation exercise to identify patient and healthcare professional priorities for primary care patient safety research. The research priorities identified a range of important gaps in the existing evidence to inform everyday practice to address primary care patient safety. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

40 CFR 52.465 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Delaware § 52.465 Original identification of plan section. (a) This section identifies the original “Air Implementation Plan for the State...

40 CFR 52.69 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.69 Original identification of plan section. (a) This section identifies the original “Air Implementation Plan for the State...

40 CFR 52.536 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Florida § 52.536 Original identification of plan section. (a) This section identifies the original “State of Florida Air Implementation...

40 CFR 52.939 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.939 Original identification of plan section. (a) This section identifies the original “Air Implementation Plan for the...

40 CFR 52.677 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Idaho § 52.677 Original identification of plan section. (a) This section identifies the original “Idaho Air Quality Implementation Plan...

40 CFR 52.1640 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section. 52.1640 Section 52.1640 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Original identification of plan section. (a) This section identifies the original “State of New Mexico...

40 CFR 52.824 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Iowa § 52.824 Original identification of plan section. (a) This section identifies the original “Air Implementation Plan for the State...

40 CFR 52.875 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.875 Original identification of plan section. (a) This section identifies the original “Air Quality Implementation Plan for the...

40 CFR 52.590 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia> § 52.590 Original identification of plan section. (a) This section identifies the original “Air Implementation Plan for the State...

40 CFR 52.200 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.200 Original identification of plan section. (a) This section identifies the original “Arkansas Plan for Implementation for...

40 CFR 52.999 - Original identification of plan section.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Original identification of plan section... PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.999 Original identification of plan section. (a) This section identifies the original “The Louisiana Air Control Commission...

A Framework for Identifying and Understanding Enterprise Systems Benefits

DEFF Research Database (Denmark)

Schubert, Petra; Williams, Susan P.

2011-01-01

Purpose – Identifying the benefits arising from implementations of enterprise systems and realizing business value remains a significant challenge for both research and industry. This paper aims to consolidate previous work. It presents a framework for investigating enterprise systems benefits...... into aspects and criteria plus an attributed appraisal value. The resulting scheme for the “three-level benefit codes” provides a greater level of detail about the nature of expected and realized benefits. Practical implications – The high level of detail and the code scheme comprising 60 different codes...... and the method for deriving the codes allows companies to identify and define benefits as well as to assess the outcome of enterprise systems implementation projects. Originality/value – The paper empirically develops an applicable benefits framework, which addresses the lack of detail of previous frameworks....

Characterization of Size, Composition and Origins of Dust in Fusion Devices. Summary Report of the Third Research Coordination Meeting

International Nuclear Information System (INIS)

Braams, B.J.

2013-02-01

Twelve experts on processes of dust in fusion experiments met at IAEA Headquarters 30 November - 02 December 2011 for the 3rd Research Coordination Meeting (RCM) of the Coordinated Research Project (CRP) on ''Characterization of size, composition and origins of dust in fusion devices.'' Participants reviewed their work done in the course of the CRP and the current state of knowledge, and they made plans for a dust database and a final CRP report. Presentations, discussions and recommendations of the RCM are summarized here. (author)

The kidney cancer research priority-setting partnership: Identifying the top 10 research priorities as defined by patients, caregivers, and expert clinicians.

Science.gov (United States)

Jones, Jennifer; Bhatt, Jaimin; Avery, Jonathan; Laupacis, Andreas; Cowan, Katherine; Basappa, Naveen; Basiuk, Joan; Canil, Christina; Al-Asaaed, Sohaib; Heng, Daniel; Wood, Lori; Stacey, Dawn; Kollmannsberger, Christian; Jewett, Michael A S

2017-12-01

It is critically important to define disease-specific research priorities to better allocate limited resources. There is growing recognition of the value of involving patients and caregivers, as well as expert clinicians in this process. To our knowledge, this has not been done this way for kidney cancer. Using the transparent and inclusive process established by the James Lind Alliance, the Kidney Cancer Research Network of Canada (KCRNC) sponsored a collaborative consensus-based priority-setting partnership (PSP) to identify research priorities in the management of kidney cancer. The final result was identification of 10 research priorities for kidney cancer, which are discussed in the context of current initiatives and gaps in knowledge. This process provided a systematic and effective way to collaboratively establish research priorities with patients, caregivers, and clinicians, and provides a valuable resource for researchers and funding agencies.

Stem cells and the origin of gliomas: A historical reappraisal with molecular advancements

Directory of Open Access Journals (Sweden)

Michael L Levy

2009-01-01

Full Text Available Michael L Levy1, Allen L Ho1,2, Samuel Hughes3, Jayant Menon1, Rahul Jandial41Division of Neurosurgery, University of California, San Diego, La Jolla, California, USA; 2Del E Webb Neurosciences, Aging and Stem Cell Research Center, The Burnham Institute for Medical Research, La Jolla, California, USA; 3Department of Neurological Surgery, Oregon Health and Science University, Portland, OR, USA; 4Division of Neurosurgery, Department of Surgery, City of Hope Cancer Center, Duarte, CA, USAAbstract: The biology of both normal and tumor development clearly possesses overlapping and parallel features. Oncogenes and tumor suppressors are relevant not only in tumor biology, but also in physiological developmental regulators of growth and differentiation. Conversely, genes identified as regulators of developmental biology are relevant to tumor biology. This is particularly relevant in the context of brain tumors, where recent evidence is mounting that the origin of brain tumors, specifically gliomas, may represent dysfunctional developmental neurobiology. Neural stem cells are increasingly being investigated as the cell type that originally undergoes malignant transformation – the cell of origin – and the evidence for this is discussed.Keywords: stem cells, gliomas, neural stem cells, brain tumors, cancer stem cells

Identifying indigenous peoples for health research in a global context: a review of perspectives and challenges.

Science.gov (United States)

Bartlett, Judith G; Madariaga-Vignudo, Lucia; O'Neil, John D; Kuhnlein, Harriet V

2007-09-01

Identifying Indigenous Peoples globally is complex and contested despite there being an estimated 370 million living in 70 countries. The specific context and use of locally relevant and clear definitions or characterizations of Indigenous Peoples is important for recognizing unique health risks Indigenous Peoples face, for understanding local Indigenous health aspirations and for reflecting on the need for culturally disaggregated data to plan meaningful research and health improvement programs. This paper explores perspectives on defining Indigenous Peoples and reflects on challenges in identifying Indigenous Peoples. Literature reviews and Internet searches were conducted, and some key experts were consulted. Pragmatic and political definitions by international institutions, including the United Nations, are presented as well as characterizations of Indigenous Peoples by governments and academic researchers. Assertions that Indigenous Peoples have about definitions of indigeneity are often related to maintenance of cultural integrity and sustainability of lifestyles. Described here are existing definitions and interests served by defining (or leaving undefined) such definitions, why there is no unified definition and implications of "too restrictive" a definition. Selected indigenous identities and dynamics are presented for North America, the Arctic, Australia and New Zealand, Latin America and the Caribbean, Asia and Africa. While health researchers need to understand the Indigenous Peoples with whom they work, ultimately, indigenous groups themselves best define how they wish to be viewed and identified for research purposes.

The Origin of Black Smock and White Collar

Science.gov (United States)

Hesapcioglu, Muhsin; Meseci Giorgetti, Filiz

2009-01-01

Although there are many empirical studies on the functions of school uniform, studies which focus on the origins of school uniform are neglected. Purpose of this study is to reveal historical origins of black smock and white collar. To achieve this purpose, a qualitative research method was adopted. As a result of the research, it was determined…

What do reviewers look for in an original research article?

Science.gov (United States)

Shankar, P R

2012-01-01

In this article common errors committed by authors especially those, whose first language is not English, while writing an original research articleis described. Avoiding common errors and improving chances of publication has also been covered. This article may resemble instruction to the author. However, tips from reviewer's eyes has been given. The abstract is the section of the paper most commonly read and care should be taken while writing this section. Keywordsare usedto retrieve articles following searches and use of words from the MeSH database is recommended.The introduction describes work already conducted in the particular area and briefly mentions how the manuscript will add to the existing knowledge.The methods section describes how the study was conducted, is written in the past tense and is often the first part of the paper to be written. The results describe what was found in the study and is usually written after the methods section.The discussion compares the study with the literature and helps to put the study findings in context. The conclusions should be based on the results of the study. The references should be written strictly according to the journal format. Language should be simple, active voice should be used and jargon avoided. Avoid directly quoting from reference articles and paraphrase these in your own words to avoid plagiarism.

Reproducibility of clinical research in critical care: a scoping review.

Science.gov (United States)

Niven, Daniel J; McCormick, T Jared; Straus, Sharon E; Hemmelgarn, Brenda R; Jeffs, Lianne; Barnes, Tavish R M; Stelfox, Henry T

2018-02-21

The ability to reproduce experiments is a defining principle of science. Reproducibility of clinical research has received relatively little scientific attention. However, it is important as it may inform clinical practice, research agendas, and the design of future studies. We used scoping review methods to examine reproducibility within a cohort of randomized trials examining clinical critical care research and published in the top general medical and critical care journals. To identify relevant clinical practices, we searched the New England Journal of Medicine, The Lancet, and JAMA for randomized trials published up to April 2016. To identify a comprehensive set of studies for these practices, included articles informed secondary searches within other high-impact medical and specialty journals. We included late-phase randomized controlled trials examining therapeutic clinical practices in adults admitted to general medical-surgical or specialty intensive care units (ICUs). Included articles were classified using a reproducibility framework. An original study was the first to evaluate a clinical practice. A reproduction attempt re-evaluated that practice in a new set of participants. Overall, 158 practices were examined in 275 included articles. A reproduction attempt was identified for 66 practices (42%, 95% CI 33-50%). Original studies reported larger effects than reproduction attempts (primary endpoint, risk difference 16.0%, 95% CI 11.6-20.5% vs. 8.4%, 95% CI 6.0-10.8%, P = 0.003). More than half of clinical practices with a reproduction attempt demonstrated effects that were inconsistent with the original study (56%, 95% CI 42-68%), among which a large number were reported to be efficacious in the original study and to lack efficacy in the reproduction attempt (34%, 95% CI 19-52%). Two practices reported to be efficacious in the original study were found to be harmful in the reproduction attempt. A minority of critical care practices with research published

Health Research and Millennium Development Goals: Identifying the Gap From Public Health Perspective.

Science.gov (United States)

El Lawindi, Mona I; Galal, Yasmine S; Khairy, Walaa A

2015-08-23

Assessing the research output within the universities could provide an effective means for tracking the Millennium Development Goals (MDGs) progress. This analytical database study was designed to assess the trend of research theses conducted by the Public Health Department (PHD), Faculty of Medicine, Cairo University during the period 1990 to 2014 as related to the: MDGS, Faculty and department research priority plans and to identify the discrepancies between researchers' priorities versus national and international research priorities. A manual search of the theses was done at the Postgraduate Library using a specially designed checklist to chart adherence of each thesis to: MDGs, Faculty and department research plans (RPs). The theses' profile showed that the highest research output was for addressing the MDGS followed by the PHD and Faculty RPs. Compliance to MDGs 5 and 6 was obvious, whereas; MDGs 2, 3, and 7 were not represented at all after year 2000. No significant difference was found between PH theses addressing the Faculty RPs and those which were not before and after 2010. A significantly lower percent of PH theses was fulfilling the PHD research priorities compared to those which were not after 2010. This study showed a definite decline in research output tackling the MDGS and PHD research priorities, with a non-significant increase in the production of theses addressing the Faculty RPs. The present study is a practical model for policy makers within the universities to develop and implement a reliable monitoring and evaluation system for assessment of research output.

Top-100 Highest-Cited Original Articles in Ischemic Stroke: A Bibliometric Analysis.

Science.gov (United States)

Malhotra, Konark; Saeed, Omar; Goyal, Nitin; Katsanos, Aristeidis H; Tsivgoulis, Georgios

2018-03-01

The total number of citations of a research article can be used to determine its impact on the scientific community. We aimed to identify the top-100 articles published on ischemic stroke and evaluate their characteristics. Based on the database of Journal Citation Reports, 934 journals were selected that published original ischemic stroke articles. We used Web of Science citation search tool to identify top-100 citation classics, i.e., articles with more than 400 citations, in the field of ischemic stroke. All original articles were evaluated for publication year, journal category, journal and its impact factor, number of total and annual citations, research topic, publishing country, and institutional affiliation. The top-100 citation classics in ischemic stroke were published from 1970 to 2015, with the decade of 1990-1999 contributing 47 articles of historical significance. Median of total citations and annual citations in our analysis were 625.0 (interquartile range [IQR] 851.3-494.5) and 35.7 (IQR 79.9-25.9), respectively. The majority of the articles originated from the United States (n = 57), focused over the medical management (n = 26), and were published in the New England Journal of Medicine or Stroke (n = 25 each) journals. The median impact factor for the journals that published top-100 ischemic stroke citation classics was 9.11 (IQR 21.49-6.11). Our list of top-100 citation classics specific to ischemic stroke provide a detailed insight into academic achievements, historical perspective and serves as a guide for the scientific progress in stroke. Copyright © 2017 Elsevier Inc. All rights reserved.

White paper on geothermal sustainability; Grundlagenpapier 'Geothermal sustainability - A review with identified research needs'

Energy Technology Data Exchange (ETDEWEB)

Rybach, L.; Megel, T.

2006-12-15

This comprehensive appendix contained in a comprehensive annual report 2006 for the Swiss Federal Office of Energy (SFOE) reviews research needs identified in connection with the topic of geothermal sustainability. It is noted that excessive production often pursued - mostly for economical reasons - can lead to the depletion of heat reservoirs. Sustainable production can be achieved with lower production rates and still provide similar total energy yields. The regeneration of geothermal resources following exploitation is discussed. The need for further research into geothermal production sustainability is noted. A doublet system realised in Riehen, Switzerland, is discussed, as is an Enhanced Geothermal System EGS using circulation in fractured rock layers. Research still needed is noted.

The 2012 dengue outbreak in Madeira: exploring the origins.

Science.gov (United States)

Wilder-Smith, A; Quam, M; Sessions, O; Rocklov, J; Liu-Helmersson, J; Franco, L; Khan, K

2014-02-27

In 2012, Madeira reported its first major outbreak of dengue. To identify the origin of the imported dengue virus, we investigated the interconnectivity via air travel between dengue-endemic countries and Madeira, and compared available sequences against GenBank. There were 22,948 air travellers to Madeira in 2012, originating from twenty-nine dengue-endemic countries; 89.6% of these international travellers originated from Venezuela and Brazil. We developed an importation index that takes into account both travel volume and the extent of dengue incidence in the country of origin. Venezuela and Brazil had by far the highest importation indices compared with all other dengue-endemic countries. The importation index for Venezuela was twice as high as that for Brazil. When taking into account seasonality in the months preceding the onset of the Madeira outbreak, this index was even seven times higher for Venezuela than for Brazil during this time. Dengue sequencing shows that the virus responsible for the Madeira outbreak was most closely related to viruses circulating in Venezuela, Brazil and Columbia. Applying the importation index, Venezuela was identified as the most likely origin of importation of dengue virus via travellers to Madeira. We propose that the importation index is a new additional tool that can help to identify and anticipate the most probable country of origin for importation of dengue into currently non-endemic countries.

Identifying optimal postmarket surveillance strategies for medical and surgical devices: implications for policy, practice and research.

Science.gov (United States)

Gagliardi, Anna R; Umoquit, Muriah; Lehoux, Pascale; Ross, Sue; Ducey, Ariel; Urbach, David R

2013-03-01

Non-drug technologies offer many benefits, but have been associated with adverse events, prompting calls for improved postmarket surveillance. There is little empirical research to guide the development of such a system. The purpose of this study was to identify optimal postmarket surveillance strategies for medical and surgical devices. Qualitative methods were used for sampling, data collection and analysis. Stakeholders from Canada and the USA representing different roles and perspectives were first interviewed to identify examples and characteristics of different surveillance strategies. These stakeholders and others they recommended were then assembled at a 1-day nominal group meeting to discuss and prioritise the components of a postmarket device surveillance system, and research needed to achieve such a system. Consultations were held with 37 participants, and 47 participants attended the 1-day meeting. They recommended a multicomponent system including reporting by facilities, clinicians and patients, supported with some external surveillance for validation and real-time trials for high-risk devices. Many considerations were identified that constitute desirable characteristics of, and means by which to implement such a system. An overarching network was envisioned to broker linkages, establish a shared minimum dataset, and support communication and decision making. Numerous research questions were identified, which could be pursued in tandem with phased implementation of the system. These findings provide unique guidance for establishing a device safety network that is based on existing initiatives, and could be expanded and evaluated in a prospective, phased fashion as it was developed.

Original Research: How to Create a Poster That Attracts an Audience.

Science.gov (United States)

Siedlecki, Sandra L

2017-03-01

: Background: Nurses developing a poster presentation for the first time who look for guidance in the literature will find many articles offering recommendations on format and style, but these are based on opinion rather than evidence. The purpose of this study was to identify the attributes of a poster that improved the chance that nursing conference attendees would read it. A mixed-methods descriptive study employing survey methodology was used to assess the perceptions of nurses attending poster sessions at a two-day nursing conference. The survey consisted of basic demographic questions, 25 items asking respondents to identify and rate the importance of variables that influenced their decision to read a poster, and several open-ended questions. Both a qualitative and quantitative analysis of the responses was performed. The two major themes that emerged from the qualitative analysis were that poster-viewing decisions were based first on aesthetics and then on relevance. The quantitative analysis identified aesthetic characteristics that were most important to nurse viewers, including overall visual appeal, color, organization, and layout; viewers determined the relevance of a poster primarily by reading its title. To develop a poster that will attract an audience, nurse researchers should keep in mind the attributes that are important to their peers and colleagues. Conference attendees are more likely to read a poster if it's on a topic that interests them, is pleasing to the eye, and has a title that's easy to read.

The Development of a Novel qPCR Assay-Set for Identifying Fecal Contamination Originating from Domestic Fowls and Waterfowl in Israel

Directory of Open Access Journals (Sweden)

Shoshanit eOhad

2016-02-01

Full Text Available The emerging Microbial Source Tracking (MST methodologies aim to identify fecal contamination originating from domestic and wild animals, and from humans. Avian MST is especially challenging, primarily because the Aves class includes both domesticated and wild species with highly diverse habitats and dietary characteristics. The quest for specific fecal bacterial MST markers can be difficult with respect to attaining sufficient assay sensitivity and specificity. The present study utilizes High Throughput Sequencing (HTS to screen bacterial 16S rRNA genes from fecal samples collected from both domestic and wild avian species. Operational taxonomic unit (OTU analysis was then performed, from which sequences were retained for downstream qPCR marker development. Identification of unique avian host DNA sequences, absent in non-avian hosts, was then carried out using a dedicated database of bacterial 16S rRNA gene taken from the Ribosomal Database Project. Six qPCR assays were developed targeting the 16S rRNA gene of Lactobacillus, Gallibacterium, Firmicutes, Fusobacteriaceae and other bacteria. Two assays (Av4143 and Av163 identified most of the avian fecal samples and demonstrated sensitivity values of 91% and 70%, respectively. The Av43 assay only identified droppings from battery hens and poultry, whereas each of the other three assays (Av24, Av13, and Av216 identified waterfowl species with lower sensitivities values. The development of an MST assay-panel, which includes both domestic and wild avian species, expands the currently known MST analysis capabilities for decoding fecal contamination.

Research Methods Identifying Correlation Between Physical Environment of Schools and Educational Paradigms

Directory of Open Access Journals (Sweden)

Grėtė Brukštutė

2016-04-01

Full Text Available The article is analysing the research that was already carried out in order to determine correlation between a physical environment of schools and educational paradigms. While selecting materials for the analysis, the attention was focused on studies conducted in the USA and European countries. Based on these studies the methodological attitudes towards coherence of the education and spatial structures were tried to identify. Homogeneity and conformity of an educational character and a physical learning environment became especially important during changes of educational conceptions. The issue how educational paradigms affect the architecture of school buildings is not yet analysed in Lithuania, therefore the results of this research could actualize a theme on correlation between educational paradigms and the architecture of school buildings and form initial guidelines for the development of the modern physical learning environment.

Compound facial expressions of emotion: from basic research to clinical applications

Science.gov (United States)

Du, Shichuan; Martinez, Aleix M.

2015-01-01

Emotions are sometimes revealed through facial expressions. When these natural facial articulations involve the contraction of the same muscle groups in people of distinct cultural upbringings, this is taken as evidence of a biological origin of these emotions. While past research had identified facial expressions associated with a single internally felt category (eg, the facial expression of happiness when we feel joyful), we have recently studied facial expressions observed when people experience compound emotions (eg, the facial expression of happy surprise when we feel joyful in a surprised way, as, for example, at a surprise birthday party). Our research has identified 17 compound expressions consistently produced across cultures, suggesting that the number of facial expressions of emotion of biological origin is much larger than previously believed. The present paper provides an overview of these findings and shows evidence supporting the view that spontaneous expressions are produced using the same facial articulations previously identified in laboratory experiments. We also discuss the implications of our results in the study of psychopathologies, and consider several open research questions. PMID:26869845

Compound facial expressions of emotion: from basic research to clinical applications.

Science.gov (United States)

Du, Shichuan; Martinez, Aleix M

2015-12-01

Emotions are sometimes revealed through facial expressions. When these natural facial articulations involve the contraction of the same muscle groups in people of distinct cultural upbringings, this is taken as evidence of a biological origin of these emotions. While past research had identified facial expressions associated with a single internally felt category (eg, the facial expression of happiness when we feel joyful), we have recently studied facial expressions observed when people experience compound emotions (eg, the facial expression of happy surprise when we feel joyful in a surprised way, as, for example, at a surprise birthday party). Our research has identified 17 compound expressions consistently produced across cultures, suggesting that the number of facial expressions of emotion of biological origin is much larger than previously believed. The present paper provides an overview of these findings and shows evidence supporting the view that spontaneous expressions are produced using the same facial articulations previously identified in laboratory experiments. We also discuss the implications of our results in the study of psychopathologies, and consider several open research questions.

The ICF Core Sets for hearing loss--researcher perspective. Part I: Systematic review of outcome measures identified in audiological research.

Science.gov (United States)

Granberg, Sarah; Dahlström, Jennie; Möller, Claes; Kähäri, Kim; Danermark, Berth

2014-02-01

To review the literature in order to identify outcome measures used in research on adults with hearing loss (HL) as part of the ICF Core Sets development project, and to describe study and population characteristics of the reviewed studies. A systematic review methodology was applied using multiple databases. A comprehensive search was conducted and two search pools were created, pool I and pool II. The study population included adults (≥ 18 years of age) with HL and oral language as the primary mode of communication. 122 studies were included. Outcome measures were distinguished by 'instrument type', and 10 types were identified. In total, 246 (pool I) and 122 (pool II) different measures were identified, and only approximately 20% were extracted twice or more. Most measures were related to speech recognition. Fifty-one different questionnaires were identified. Many studies used small sample sizes, and the sex of participants was not revealed in several studies. The low prevalence of identified measures reflects a lack of consensus regarding the optimal outcome measures to use in audiology. Reflections and discussions are made in relation to small sample sizes and the lack of sex differentiation/descriptions within the included articles.

Identification of High Confidence Nuclear Forensics Signatures. Results of a Coordinated Research Project and Related Research

International Nuclear Information System (INIS)

2017-08-01

The results of a Coordinated Research Project and related research on the identification of high confidence nuclear forensic isotopic, chemical and physical data characteristics, or signatures, provides information on signatures that can help identify the origin and history of nuclear and other radioactive material encountered out of regulatory control. This research report compiles findings from investigations of materials obtained from throughout the nuclear fuel cycle to include radioactive sources. The report further provides recent results used to identify, analyse in the laboratory, predict and interpret these signatures relative to the requirements of a nuclear forensics examination. The report describes some of the controls on the incorporation and persistence of these signatures in these materials as well as their potential use in a national system of identification to include a national nuclear forensics library.

Scientometric methods for identifying emerging technologies

Science.gov (United States)

Abercrombie, Robert K; Schlicher, Bob G; Sheldon, Frederick T

2015-11-03

Provided is a method of generating a scientometric model that tracks the emergence of an identified technology from initial discovery (via original scientific and conference literature), through critical discoveries (via original scientific, conference literature and patents), transitioning through Technology Readiness Levels (TRLs) and ultimately on to commercial application. During the period of innovation and technology transfer, the impact of scholarly works, patents and on-line web news sources are identified. As trends develop, currency of citations, collaboration indicators, and on-line news patterns are identified. The combinations of four distinct and separate searchable on-line networked sources (i.e., scholarly publications and citation, worldwide patents, news archives, and on-line mapping networks) are assembled to become one collective network (a dataset for analysis of relations). This established network becomes the basis from which to quickly analyze the temporal flow of activity (searchable events) for the example subject domain.

Loneliness, immigration background and self-identified ethnicity

DEFF Research Database (Denmark)

Madsen, Katrine Rich; Damsgaard, Mogens Trab; Jervelund, Signe Smith

2016-01-01

an increased risk of loneliness compared to adolescents with a Danish origin. The results also suggest that adolescents’ self-identified ethnicity plays an essential role but differently for immigrants and descendants: identifying with the Danish majority was protective against loneliness among immigrants...

The origins of options.

Science.gov (United States)

Smaldino, Paul E; Richerson, Peter J

2012-01-01

Most research on decision making has focused on how human or animal decision makers choose between two or more options, posed in advance by the researchers. The mechanisms by which options are generated for most decisions, however, are not well understood. Models of sequential search have examined the trade-off between continued exploration and choosing one's current best option, but still cannot explain the processes by which new options are generated. We argue that understanding the origins of options is a crucial but untapped area for decision making research. We explore a number of factors which influence the generation of options, which fall broadly into two categories: psycho-biological and socio-cultural. The former category includes factors such as perceptual biases and associative memory networks. The latter category relies on the incredible human capacity for culture and social learning, which doubtless shape not only our choices but the options available for choice. Our intention is to start a discussion that brings us closer toward understanding the origins of options.

The origin of the universe and nuclear synthesis

Directory of Open Access Journals (Sweden)

J. P. F. Sellschop

1988-03-01

Full Text Available The origin of the universe and nuclear synthesis are discussed in this paper. The concept of the “Big Bang” is introduced in cosmology from observational evidence that the universe is expanding. The language of elementary particle physics is used to describe the evolution of the universe starting at a very small fraction of a second after the "Big Bang”. Various “Eras” are identified during which certain nuclear processes predominate. At a later stage the remarkable nuclear synthesis of carbon takes place, leading to the evolution of other elements. Neutrino measurements are important to validate physical theories in this field and some results of such measurements by the WITS-CSIR Schonland Research Centre are presented.

Towards a community effort to identify ethical principles for research in hydrology

Science.gov (United States)

Montanari, Alberto

2010-05-01

The hydrological community in Europe is growing rapidly in both size and, more importantly, scientific relevance and integrity. The Hydrological Sciences (HS) Division of EGU actively is promoting the above development by identifying research targets, stimulating the involvement of young scientists and managing a scientific open access journal based on a public peer review process. The management of the Division itself and the organisation of the General Assembly are carried out transparently, with the aim to seek an improved involvement of top and young scientists, with a bottom up approach. I believe the HS community is animated by a strong enthusiasm which, however, is not adequately supported by economical funding. In my opinion this is a major problem which HS should consider and discuss. The relevance of the societal and environmental problems dealt with by hydrologists, in a professional way and with exceptional scientific skills, is without doubt and therefore the limited amount of funding is not justified in practice. In my opinion, in order to refine the structure of the HS community, and promote its visibility, we should formally identify HS ethical principles for research in environmental science. The principles should highlight the role of hydrology as well as the ethical and scientific solidity of the HS community. Establishing ethical principles is even more important in view of the transparent approach HS is adopting for reviewing and publishing contributions and in view of the increasing need to transparently prove how public funding for research is administered. Establishing ethical principles for hydrology is not a trivial task. Hydrology is characterised by a relevant uncertainty in data, models and parameters. Hydrology is also relying on a large variety of approaches, ranging from statistical to physically based. The purpose of this poster is to present a collection of ethical principles for scientific research presented by the literature and

One Health approach to identify research needs in bovine and human babesioses: workshop report

Directory of Open Access Journals (Sweden)

McElwain Terry F

2010-04-01

Full Text Available Abstract Background Babesia are emerging health threats to humans and animals in the United States. A collaborative effort of multiple disciplines to attain optimal health for people, animals and our environment, otherwise known as the One Health concept, was taken during a research workshop held in April 2009 to identify gaps in scientific knowledge regarding babesioses. The impetus for this analysis was the increased risk for outbreaks of bovine babesiosis, also known as Texas cattle fever, associated with the re-infestation of the U.S. by cattle fever ticks. Results The involvement of wildlife in the ecology of cattle fever ticks jeopardizes the ability of state and federal agencies to keep the national herd free of Texas cattle fever. Similarly, there has been a progressive increase in the number of cases of human babesiosis over the past 25 years due to an increase in the white-tailed deer population. Human babesiosis due to cattle-associated Babesia divergens and Babesia divergens-like organisms have begun to appear in residents of the United States. Research needs for human and bovine babesioses were identified and are presented herein. Conclusions The translation of this research is expected to provide veterinary and public health systems with the tools to mitigate the impact of bovine and human babesioses. However, economic, political, and social commitments are urgently required, including increased national funding for animal and human Babesia research, to prevent the re-establishment of cattle fever ticks and the increasing problem of human babesiosis in the United States.

On the biosynthetic origin of carminic acid

DEFF Research Database (Denmark)

Rasmussen, Silas A.; Kongstad, Kenneth T; Khorsand-Jamal, Paiman

2018-01-01

provides solid evidence of a polyketide, rather than a shikimate, origin of coccid pigments. Based on the newly identified compounds, we present a detailed biosynthetic scheme that accounts for the formation of carminic acid (CA) in D. coccus and all described coccid pigments which share a flavokermesic...... distribution suggests a common evolutionary origin for the trait in all coccid dye producing insect species....

Uncited Research Articles in Popular United States General Radiology Journals.

Science.gov (United States)

Rosenkrantz, Andrew B; Chung, Ryan; Duszak, Richard

2018-05-03

This study aimed to characterize articles in popular general radiology journals that go uncited for a decade after publication. Using the Web of Science database, we identified annual citation counts for 13,459 articles published in Radiology, American Journal of Roentgenology, and Academic Radiology between 1997 and 2006. From this article cohort, we then identified all original research articles that accrued zero citations within a decade of publication. A concurrent equal-sized cohort of most cited articles was created. Numerous characteristics of the uncited and most cited articles were identified and compared. Only 47 uncited articles went uncited for a decade after publication. When compared to the 47 most cited articles over that same window, the uncited articles were significantly (P articles, uncited articles also had significantly (P articles published in popular general radiology journals, only a very small number of original research investigations remained uncited a decade after publication. Given that citations reflect the impact of radiology research, this observation suggests that journals are appropriately selecting meaningful work. Investigators seeking to avoid futile publication might consider their research initiatives in light of these characteristics. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

Collaborative Researchers or Cold Warriors? The Origins, Activities, and Legacy of the Smithsonian’s Institute of Social Anthropology

Directory of Open Access Journals (Sweden)

A. Peter Castro

2010-11-01

Full Text Available International research collaboration is increasingly popular, providing many scholarly and practical benefits. These collaborative endeavors also encounter obstacles and costs, including ones involving issues of power and professional ethics. My study seeks to widen our understanding of international collaborative social science research by examining the complex origins, diverse activities, and clouded legacy of the Smithsonian Institution’s Institute of Social Anthropology (ISA. The ISA was an innovative collaborative teaching and research program founded by Julian Steward during World War II to meet many goals, including increasing social science capacity in Latin America, expanding knowledge about contemporary cultural change, strengthening area expertise among U.S. scholars, and promoting closer relations among the peoples of the Americas. The ISA provided career-enhancing opportunities for U.S. and Latin American scholars, while helping to pioneer applied medical anthropology. I take issue with recent analysts who portray the ISA as promoting, including through covert research, U.S. hegemonic interests seeking to control rural Latin America.

The Telescoping Phenomenon: Origins in Gender Bias and Implications for Contemporary Scientific Inquiry.

Science.gov (United States)

Marks, Katherine R; Clark, Claire D

2018-05-12

In an article published in International Journal of the Addictions in 1989, Nick Piazza and his coauthors described "telescoping," an accelerated progression through "landmark symptoms" of alcoholism, among a sample of recovering women. The aim of this critical analysis is to apply a feminist philosophy of science to examine the origins of the framework of telescoping research and its implications for contemporary scientific inquiry. A feminist philosophy of science framework is outlined and applied to key source publications of telescoping literature drawn from international and United States-based peer-reviewed journals published beginning in 1952. A feminist philosophy of science framework identifies gender bias in telescoping research in three ways. First, gender bias was present in the early conventions that laid the groundwork for telescoping research. Second, a "masculine" framework was present in the methodology guiding telescoping research. Third, gender bias was present in the interpretation of results as evidenced by biased comparative language. Telescoping research contributed to early evidence of critical sex and gender differences helping to usher in women's substance abuse research more broadly. However, it also utilized a "masculine" framework that perpetuated gender bias and limited generative, novel research that can arise from women-focused research and practice. A feminist philosophy of science identifies gender bias in telescoping research and provides an alternative, more productive approach for substance abuse researchers and clinicians.

Characteristics and trends of radiology research: a survey of original articles published in AJR and Radiology between 2001 and 2010.

Science.gov (United States)

Lim, Kyoung Ja; Yoon, Dae Young; Yun, Eun Joo; Seo, Young Lan; Baek, Sora; Gu, Dong Hyeon; Yoon, Soo Jeong; Han, Ari; Ku, You Jin; Kim, Sam Soo

2012-09-01

To determine the characteristics and trends of the original articles published in two major American radiology journals, AJR American Journal of Roentgenology (AJR) and Radiology, between 2001 and 2010. This was a retrospective bibliometric analysis that did not involve human subjects and was exempt from institutional review board approval. All 6542 original articles published in AJR and Radiology between 2001 and 2010 were evaluated. The following information was abstracted from each article: radiologic subspecialty, radiologic technique used, type of research, sample size, study design, statistical analysis, study outcome, declared funding, number of authors, affiliation of the first author, and country of the first author. In addition, all the variables examined were presented along with the trend over time. The most common subspecialty of study was abdominal (1219 of 6542, 18.6%), followed by vascular/interventional (804 of 6542, 12.3%). A total of 3744 (57.2%) original articles used magnetic resonance (MR) imaging or computed tomography (CT), 5495 (84.1%) were clinical research articles, 3060 (46.8%) had sample size of more than 50, 4087 (62.5%) were retrospective, 4714 (72.1%) performed statistical analysis, 6225 (95.2%) showed positive study outcome, 4784 (73.1%) were not funded, 3942 (60.3%) had four to seven authors, and 5731 (87.6%) were written by the primary author who was from a department of radiology or radiology-related specialties. The United States published 45.5% (2975 of 6542) of the articles, followed by Japan (n = 525, 8.0%), Germany (n = 485, 7.4%), and South Korea (n = 455, 7.0%). In the time trend analysis, the following variables showed a significantly positive trend: cardiac subspecialty, CT and MR imaging as the radiologic techniques, type of research as other (nonbasic, nonclinical), sample size of more than 50, four to seven as the number of authors, medicine-related department of the first author, and South Korea and Italy as

Early Origins of Child Obesity: Bridging Disciplines and Phases of Development - September 30–October 1, 2010

Science.gov (United States)

Christoffel, Katherine Kaufer; Wang, Xiaobin; Binns, Helen J.

2012-01-01

This report summarizes a conference: “Early Origins of Child Obesity: Bridging Disciplines and Phases of Development”, held in Chicago on September 30–October 1, 2010. The conference was funded in part by the National Institutes of Health and the Williams Heart Foundation, to achieve the conference objective: forging a next-step research agenda related to the early origins of childhood obesity. This research agenda was to include working with an array of factors (from genetic determinants to societal ones) along a continuum from prenatal life to age 7, with an emphasis on how the developing child deals with the challenges presented by his/her environment (prenatal, parental, nutritional, etc.). The conference offered a unique opportunity to facilitate communication and planning of future work among a variety of researchers whose work separately addresses different periods in early life. Over the span of two days, speakers addressed existing, critical research topics within each of the most-studied age ranges. On the final day, workshops fostered the discussion needed to identify the highest priority research topics related to linking varied early factor domains. These are presented for use in planning future research and research funding. PMID:23443002

Identifying research priorities in anaesthesia and perioperative care: final report of the joint National Institute of Academic Anaesthesia/James Lind Alliance Research Priority Setting Partnership

OpenAIRE

Boney, O.; Bell, M.; Bell, N.; Conquest, A.; Cumbers, M.; Drake, S.; Galsworthy, M.; Gath, J.; Grocott, M. P.; Harris, E.; Howell, S.; Ingold, A.; Nathanson, M. H.; Pinkney, T.; Metcalf, L.

2015-01-01

Objective To identify research priorities for Anaesthesia and Perioperative Medicine. Design Prospective surveys and consensus meetings guided by an independent adviser. Setting UK. Participants 45 stakeholder organisations (25 professional, 20 patient/carer) affiliated as James Lind Alliance partners. Outcomes First ?ideas-gathering? survey: Free text research ideas and suggestions. Second ?prioritisation? survey: Shortlist of ?summary? research questions (derived from the first survey) rank...

Original Research Article Pharmaceutical Care Implementation

African Journals Online (AJOL)

Erah

International Journal of Health Research, June 2011; 4(2): 91-97. © Poracom ..... Pharmacy School. Journals. Post-Graduate level. Internet. Others. 64. 34. 48. 22. 2. 61.0. 52.5 .... empathy, privacy and good communication skill are paramount.

Marketing Suggestions for Home Original Chicken, Hefei China

OpenAIRE

Cheng, Ran

2014-01-01

The research “Marketing Suggestions for Home Original Chicken, Hefei China” was commissioned by Home Original Chicken Co. Ltd, which is the biggest Chinese fast-food restaurant chain in Anhui Province. The theory needed in the research was marketing mix strategies. Marketing mix consists of product, price, place and promotion. The marketing strategies contain product decisions (including individual products decisions, product line decisions, product mix decisions), price decisions (contai...

37 CFR 1.804 - Time of making an original deposit.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Time of making an original... of Biological Material § 1.804 Time of making an original deposit. (a) Whenever a biological material is specifically identified in an application for patent as filed, an original deposit thereof may be...

Terra Cognita: Graduate Students in the Archives. A Retrospective on the CLIR Mellon Fellowships for Dissertation Research in Original Sources. CLIR Publication No. 170

Science.gov (United States)

Council on Library and Information Resources, 2016

2016-01-01

"Terra Cognita" surveys the current landscape of archival research and the experiences of emerging scholars seeking to navigate it. Drawing on data from the Council on Library and Information Resources' (CLIR's) Mellon Fellowships for Dissertation Research in Original Sources, the report takes an in-depth look at how the conditions and…

How well does climate change and human health research match the demands of policymakers? A scoping review.

Science.gov (United States)

Hosking, Jamie; Campbell-Lendrum, Diarmid

2012-08-01

In 2008, the World Health Organization (WHO) Member States passed a World Health Assembly resolution that identified the following five priority areas for research and pilot projects on climate change and human health: health vulnerability, health protection, health impacts of mitigation and adaptation policies, decision-support and other tools, and costs of health protection from climate change. To assess the extent to which recently published research corresponds to these priorities, we undertook a scoping review of original research on climate change and human health. Scoping reviews address topics that are too broad for a systematic review and commonly aim to identify research gaps in existing literature. We also assessed recent publication trends for climate change and health research. We searched for original quantitative research published from 2008 onward. We included disease burden studies that were specific to climate change and health and included intervention studies that focused on climate change and measured health outcomes. We used MEDLINE, Embase, and Web of Science databases and extracted data on research priority areas, geographic regions, health fields, and equity (systematic differences between advantaged and disadvantaged social groups). We identified 40 eligible studies. Compared with other health topics, the number of climate change publications has grown rapidly, with a larger proportion of reviews or editorials. Recent original research addressed four of the five priority areas identified by the WHO Member States, but we found no eligible studies of health adaptation interventions, and most of the studies focused on high-income countries. Climate change and health is a rapidly growing area of research, but quantitative studies remain rare. Among recently published studies, we found gaps in adaptation research and a deficit of studies in most developing regions. Funders and researchers should monitor and respond to research gaps to help

The use of sterol distributions combined with compound specific isotope analyses as a tool to identify the origin of fecal contamination in rivers.

Science.gov (United States)

Biache, Coralie; Philp, R Paul

2013-03-01

The sterol distributions of 9 sediment samples from the Illinois River Basin (OK and AR, USA) were examined in order to identify the source of fecal contamination. The samples were extracted with organic solvent using sonication and the fractions containing the sterols were isolated and analyzed by gas chromatography-mass spectrometry. The sterol distributions of the Illinois River samples were dominated by phytosterols. They were compared to those of different animal feces and manures using a principal component analysis and correspondence appeared between the sediments and one group of chicken feces samples. Gas chromatography-isotope ratio mass spectrometry analyses were also performed to determine the δ(13)C values for the phytosterols and to get an indication of their origin based on the C(3)/C(4) plant signatures. The δ(13)C values obtained ranged from -30.6 ‰ to -17.4 ‰ (VPDB) corresponding to a mixed signature between C(3) and C(4) plants, indicating a C(4) plant contribution to the C(3) plant natural background. These observations indicate that a proportion of the phytosterols originated from chicken feces. Copyright © 2012 Elsevier Ltd. All rights reserved.

The origin of SEP events: New research collaboration and network on space weather

Science.gov (United States)

Miteva, Rositsa; Kashapova, Larisa; Myagkova, Irina; Meshalkina, Nataliia; Petrov, Nikola; Bogomolov, Andrey; Myshyakov, Ivan; Tsvetkov, Tsvetan; Danov, Dimitar; Zdanov, Dmitriy

2017-11-01

A new project on the solar energetic particles (SEPs) and their solar origins (flares and coronal mass ejections) is described here. The main aim of this project is to answer the question - whether the SEPs observed in situ are driven by flares, by CMEs or both accelerators contribute to an extent which varies from event to event - by deducing a quantitative measure of the flare vs. CME contribution, duration and efficiency. New observations (SONG/Koronas-F, Relec/Vernov) and new approaches of analysis will be utilized (e.g., magnetic topology of active regions using 3D extrapolation techniques of detailed case studies together with statistical analysis of the phenomena). In addition, the identification of the uncertainty limits of SEP injection, onset time and testing the validity of assumptions often taken for granted (association procedures, solar activity longitudinal effects, correlation analysis, etc.) are planned. The project outcomes have the capacity to contribute to other research fields for improvement of modeling schemes and forecasting methods of space weather events.

Identification of geographical origin of sesame seeds by near infrared spectroscopy

International Nuclear Information System (INIS)

Kwon, Y.K.; Cho, R.K.

1998-01-01

Geographical origin of the Korean, Chinese and Japanese sesame seeds were identified very high accuracy by NIR spectroscopy. The NIR instrument of filter type showed the same accuracy of the monochromator scanning type to identify the geographical origin of the sesame seeds. in case of adulteration between the Korean and Chinese sesame seeds, the ratio of addition could be determined about 10% error level. The reason of identification of geographical origin by NIR spectroscopy, it was supposed to the difference of oil cake substance

Patterns of symptom control and palliative care-focused original research articles in the International Journal of Radiation Oncology *Biology* Physics and the Radiotherapy and Oncology Journal, 2005-2014.

Science.gov (United States)

Shi, Diana D; DiGiovanni, Julia; Skamene, Sonia; Noveroske Philbrick, Sarah; Wang, Yanbing; Barnes, Elizabeth A; Chow, Edward; Sullivan, Adam; Balboni, Tracy A

2018-04-01

A significant portion of radiation treatment (30-40%) is delivered with palliative intent. Given the frequency of palliative care (PC) in radiation oncology, we determined the patterns of research focusing on symptom control and palliative care (SCPC) in two prominent radiation oncology journals from 2005-2014. Original research manuscripts published from 2005-2014 in the International Journal of Radiation Oncology *Biology* Physics (Red Journal) and the Radiotherapy and Oncology Journal (Green Journal) were reviewed to categorize articles as PC and/or SCPC. Articles were categorized as PC if it pertained to any aspect of treatment of metastatic cancer, and as SCPC if symptom control in the metastatic cancer setting was the goal of the research inquiry and/or any domain of palliative clinical practice guidelines was the goal of research inquiry. From 2005-2014, 4.9% (312/6,386) of original research articles published in the Red Journal and 3.5% (84/2,406) published in the Green Journal pertained to metastatic cancer, and were categorized as PC. In the Red Journal, 1.3% (84/6,386) of original research articles were categorized as SCPC; 1.3% (32/2,406) of articles in the Green Journal were categorized as SCPC. There was no trend observed in the proportion of SCPC articles published over time in the Red Journal (P=0.76), the Green Journal (P=0.48), or both journals in aggregate (P=0.38). Despite the fact that palliative radiotherapy is a critical part of radiation oncology practice, PC and SCPC-focused original research is poorly represented in the Red Journal and the Green Journal.

New research on the origin of mottled clay in Quaternary basins in the coastal area of south China

Science.gov (United States)

Wang, Jing; Chen, Zhen; Gao, Quanzhou; Chen, Guoneng

2018-06-01

Last Glacial Maximum (LGM) mottled clay occurs widely in Late Quaternary basins in south China coastal areas. Current research attributes its origin to exposure weathering of Late Pleistocene marine/fluvial deposits during the LGM. However, field data suggest that this is not the case as there is no gradual transition in lithology, grain size, structure and material composition among these layers. Instead, the mottled clay possesses sedimentary characteristics of exotic dust. In this study, three typical drill cores in the Pearl River Delta were studied using grain size analysis, diffuse reflection spectroscopy (DRS) and geochemical analysis to ascertain the clay's sedimentary characteristics and origin. Grain size distribution patterns and parameters of the mottled clay were similar to those of a typical loess, indicating aeolian origin. In DRS curves, the peak height of hematite > goethite, indicating that the mottled clay had not experienced strong hydration and constitutes a continental product. This conforms to a typical loess but differs from the underlying marine/fluvial deposits. The chemical composition of the mottled clay was homogeneous in the vertical and planar directions. Upper continental crust (UCC) normalized curves of major and trace elements of the mottled clay were close to the average UCC and were consistent with typical aeolian deposits. The spatial and temporal distribution characteristics and relationship with the underlying layer suggest that the mottled clay was a loess-like deposit during the LGM and its mottled structure originated from strong modification of oxidation during the postglacial period after homogeneous dust had accumulated.

Closing the gap between research and management

Science.gov (United States)

Deborah M. Finch; Marcia Patton-Mallory

1993-01-01

In this paper, we evaluate the reasons for gaps in communication between researchers and natural resource managers and identify methods to close these gaps. Gaps originate from differing patterns of language use, disparities in organizational culture and values, generation of knowledge that is too narrowly-focused to solve complex problems, failure by managers to relay...

Identifying the Transgender Population in the Medicare Program

Science.gov (United States)

Proctor, Kimberly; Haffer, Samuel C.; Ewald, Erin; Hodge, Carla; James, Cara V.

2016-01-01

Abstract Purpose: To identify and describe the transgender population in the Medicare program using administrative data. Methods: Using a combination of International Classification of Diseases ninth edition (ICD-9) codes relating to transsexualism and gender identity disorder, we analyzed 100% of the 2013 Centers for Medicare & Medicaid Services (CMS) Medicare Fee-For-Service (FFS) “final action” claims from both institutional and noninstitutional providers (∼1 billion claims) to identify individuals who may be transgender Medicare beneficiaries. To confirm, we developed and applied a multistage validation process. Results: Four thousand ninety-eight transgender beneficiaries were identified, of which ∼90% had confirmatory diagnoses, billing codes, or evidence of a hormone prescription. In general, the racial, ethnic, and geographic distribution of the Medicare transgender population tends to reflect the broader Medicare population. However, age, original entitlement status, and disease burden of the transgender population appear substantially different. Conclusions: Using a variety of claims information, ranging from claims history to additional diagnoses, billing modifiers, and hormone prescriptions, we demonstrate that administrative data provide a valuable resource for identifying a lower bound of the Medicare transgender population. In addition, we provide a baseline description of the diversity and disease burden of the population and a framework for future research. PMID:28861539

Research Progresses of Halo Streams in the Solar Neighborhood

Science.gov (United States)

Xi-long, Liang; Jing-kun, Zhao; Yu-qin, Chen; Gang, Zhao

2018-01-01

The stellar streams originated from the Galactic halo may be detected when they pass by the solar neighborhood, and they still keep some information at their birth times. Thus, the investigation of halo streams in the solar neighborhood is very important for understanding the formation and evolution of our Galaxy. In this paper, the researches of halo streams in the solar neighborhood are briefly reviewed. We have introduced the methods how to detect the halo streams and identify their member stars, summarized the progresses in the observation of member stars of halo streams and in the study of their origins, introduced in detail how to analyze the origins of halo streams in the solar neighborhood by means of numerical simulation and chemical abundance, and finally discussed the prospects of the LAMOST and GAIA in the research of halo streams in the solar neighborhood.

Rediscovering Paideia and the Meaning of a Scholarly Career: Rejoinder to "Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory"

Science.gov (United States)

Antonacopoulou, Elena P.

2016-01-01

In "Identifying Research Topic Development in Business and Management Education Research Using Legitimation Code Theory," authors J.B. Arbaugh, Charles J. Fornaciari, and Alvin Hwang ("Journal of Management Education," December 2016 vol. 40 no. 6 p654-691, see EJ1118407) used citation analysis to track the development of…

Group-effort Applied Research: Expanding Opportunities for Undergraduate Research through Original, Class-Based Research Projects

Science.gov (United States)

Moore, Sean D.; Teter, Ken

2014-01-01

Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with…

Identifying nurse staffing research in Medline: development and testing of empirically derived search strategies with the PubMed interface.

Science.gov (United States)

Simon, Michael; Hausner, Elke; Klaus, Susan F; Dunton, Nancy E

2010-08-23

The identification of health services research in databases such as PubMed/Medline is a cumbersome task. This task becomes even more difficult if the field of interest involves the use of diverse methods and data sources, as is the case with nurse staffing research. This type of research investigates the association between nurse staffing parameters and nursing and patient outcomes. A comprehensively developed search strategy may help identify nurse staffing research in PubMed/Medline. A set of relevant references in PubMed/Medline was identified by means of three systematic reviews. This development set was used to detect candidate free-text and MeSH terms. The frequency of these terms was compared to a random sample from PubMed/Medline in order to identify terms specific to nurse staffing research, which were then used to develop a sensitive, precise and balanced search strategy. To determine their precision, the newly developed search strategies were tested against a) the pool of relevant references extracted from the systematic reviews, b) a reference set identified from an electronic journal screening, and c) a sample from PubMed/Medline. Finally, all newly developed strategies were compared to PubMed's Health Services Research Queries (PubMed's HSR Queries). The sensitivities of the newly developed search strategies were almost 100% in all of the three test sets applied; precision ranged from 6.1% to 32.0%. PubMed's HSR queries were less sensitive (83.3% to 88.2%) than the new search strategies. Only minor differences in precision were found (5.0% to 32.0%). As with other literature on health services research, nurse staffing studies are difficult to identify in PubMed/Medline. Depending on the purpose of the search, researchers can choose between high sensitivity and retrieval of a large number of references or high precision, i.e. and an increased risk of missing relevant references, respectively. More standardized terminology (e.g. by consistent use of the

The RNA-world and co-evolution hypothesis and the origin of life: Implications, research strategies and perspectives

Science.gov (United States)

Lahav, Noam

1993-01-01

The applicability of the RNA-world and co-evolution hypothesis to the study of the very first stages of the origin of life is discussed. The discussion focuses on the basic differences between the two hypotheses and their implications, with regard to the reconstruction methodology, ribosome emergence, balance between ribozymes and protein enzymes, and their major difficultites. Additional complexities of the two hypotheses, such as membranes and the energy source of the first reactions, are not treated in the present work. A central element in the proposed experimental strategies is the study of the catalytic activites of very small peptides and RNA-like oligomers, according to existing, as well as to yet-to-be-invented scenarios of the two hypothesis under consideration. It is suggested that the novel directed molecular evolution technology, and molecular computational modeling, can be applied to this research. This strategy is assumed to be essential for the suggested goal of future studies of the origin of life, namely, the establishment of a `Primordial Darwinian entity'.

The RNA-world and co-evolution hypotheses and the origin of life: Implications, research strategies and perspectives

Science.gov (United States)

Lahav, Noam

1993-12-01

The applicability of the RNA-world and co-evolution hypotheses to the study of the very first stages of the origin of life is discussed. The discussion focuses on the basic differences between the two hypotheses and their implications, with regard to the reconstruction methodology, ribosome emergence, balance between ribozymes and protein enzymes, and their major difficulties. Additional complexities of the two hypotheses, such as membranes and the energy source of the first reactions, are not treated in the present work. A central element in the proposed experimental strategies is the study of the catalytic activities of very small peptides and RNA-like oligomers, according to existing, as well as to yet-to-be-invented scenarios of the two hypotheses under consideration. It is suggested that the noveldirected molecular evolution technology, andmolecular computational modeling, can be applied to this research. This strategy is assumed to be essential for the suggested goal of future studies of the origin of life, namely, the establishment of a ‘Primordial Darwinian entity’.

Ages of origin and destination for a difference in life expectancy

Directory of Open Access Journals (Sweden)

Elwood Carlson

2006-03-01

Full Text Available Decomposition of a difference in life expectancies may identify ages at which the difference originates in mortality differences, or may identify age at which the difference results in different values of person-years lived (life table population. This study shows that the two approaches are orthogonally related to each other, and derives an origin-destination decomposition matrix in which summing in one direction produces Andreev's origin-decomposition results, while summing in the other direction produces destination-decomposition corresponding to directly-observed differences in nLx values.

Original Research Prevalence and distribution of Schistosoma ...

African Journals Online (AJOL)

control. As prevalence falls, diagnostics can identify high transmission areas, monitor disease trends, and guide evidence-based control strategies. Introduction ..... Fever. 255. 0.50. Abdominal pain. 295. 0.015. Blurred vision. 26. 0.44. Blood in ...

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review.

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Nicholls, Stuart G; Hayes, Tavis P; Brehaut, Jamie C; McDonald, Michael; Weijer, Charles; Saginur, Raphael; Fergusson, Dean

2015-01-01

To date there is no established consensus of assessment criteria for evaluating research ethics review. We conducted a scoping review of empirical research assessing ethics review processes in order to identify common elements assessed, research foci, and research gaps to aid in the development of assessment criteria. Electronic searches of Ovid Medline, PsychInfo, and the Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED, were conducted. After de-duplication, 4234 titles and abstracts were reviewed. Altogether 4036 articles were excluded following screening of titles, abstracts and full text. A total of 198 articles included for final data extraction. Few studies originated from outside North America and Europe. No study reported using an underlying theory or framework of quality/effectiveness to guide study design or analyses. We did not identify any studies that had involved a controlled trial--randomised or otherwise--of ethics review procedures or processes. Studies varied substantially with respect to outcomes assessed, although tended to focus on structure and timeliness of ethics review. Our findings indicate a lack of consensus on appropriate assessment criteria, exemplified by the varied study outcomes identified, but also a fragmented body of research. To date research has been largely quantitative, with little attention given to stakeholder experiences, and is largely cross sectional. A lack of longitudinal research to date precludes analyses of change or assessment of quality improvement in ethics review.

Group-Effort Applied Research (GEAR): Expanding Opportunities for Undergraduate Research Through Original, Class-Based Research Projects

Science.gov (United States)

Moore, Sean D.; Teter, Ken

2014-01-01

Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student - one mentor model for undergraduate research. Group-Effort Applied Research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's lab. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student - one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this paper, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. PMID:24898007

Identifying diffusion patterns of research articles on Twitter: A case study of online engagement with open access articles.

Science.gov (United States)

Alperin, Juan Pablo; Gomez, Charles J; Haustein, Stefanie

2018-03-01

The growing presence of research shared on social media, coupled with the increase in freely available research, invites us to ask whether scientific articles shared on platforms like Twitter diffuse beyond the academic community. We explore a new method for answering this question by identifying 11 articles from two open access biology journals that were shared on Twitter at least 50 times and by analyzing the follower network of users who tweeted each article. We find that diffusion patterns of scientific articles can take very different forms, even when the number of times they are tweeted is similar. Our small case study suggests that most articles are shared within single-connected communities with limited diffusion to the public. The proposed approach and indicators can serve those interested in the public understanding of science, science communication, or research evaluation to identify when research diffuses beyond insular communities.

Identification of Differentially Expressed Genes between Original Breast Cancer and Xenograft Using Machine Learning Algorithms

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Deling Wang

2018-03-01

Full Text Available Breast cancer is one of the most common malignancies in women. Patient-derived tumor xenograft (PDX model is a cutting-edge approach for drug research on breast cancer. However, PDX still exhibits differences from original human tumors, thereby challenging the molecular understanding of tumorigenesis. In particular, gene expression changes after tissues are transplanted from human to mouse model. In this study, we propose a novel computational method by incorporating several machine learning algorithms, including Monte Carlo feature selection (MCFS, random forest (RF, and rough set-based rule learning, to identify genes with significant expression differences between PDX and original human tumors. First, 831 breast tumors, including 657 PDX and 174 human tumors, were collected. Based on MCFS and RF, 32 genes were then identified to be informative for the prediction of PDX and human tumors and can be used to construct a prediction model. The prediction model exhibits a Matthews coefficient correlation value of 0.777. Seven interpretable interactions within the informative gene were detected based on the rough set-based rule learning. Furthermore, the seven interpretable interactions can be well supported by previous experimental studies. Our study not only presents a method for identifying informative genes with differential expression but also provides insights into the mechanism through which gene expression changes after being transplanted from human tumor into mouse model. This work would be helpful for research and drug development for breast cancer.

Identification of Differentially Expressed Genes between Original Breast Cancer and Xenograft Using Machine Learning Algorithms.

Science.gov (United States)

Wang, Deling; Li, Jia-Rui; Zhang, Yu-Hang; Chen, Lei; Huang, Tao; Cai, Yu-Dong

2018-03-12

Breast cancer is one of the most common malignancies in women. Patient-derived tumor xenograft (PDX) model is a cutting-edge approach for drug research on breast cancer. However, PDX still exhibits differences from original human tumors, thereby challenging the molecular understanding of tumorigenesis. In particular, gene expression changes after tissues are transplanted from human to mouse model. In this study, we propose a novel computational method by incorporating several machine learning algorithms, including Monte Carlo feature selection (MCFS), random forest (RF), and rough set-based rule learning, to identify genes with significant expression differences between PDX and original human tumors. First, 831 breast tumors, including 657 PDX and 174 human tumors, were collected. Based on MCFS and RF, 32 genes were then identified to be informative for the prediction of PDX and human tumors and can be used to construct a prediction model. The prediction model exhibits a Matthews coefficient correlation value of 0.777. Seven interpretable interactions within the informative gene were detected based on the rough set-based rule learning. Furthermore, the seven interpretable interactions can be well supported by previous experimental studies. Our study not only presents a method for identifying informative genes with differential expression but also provides insights into the mechanism through which gene expression changes after being transplanted from human tumor into mouse model. This work would be helpful for research and drug development for breast cancer.

Particulate matter and atherosclerosis: a bibliometric analysis of original research articles published in 1973–2014

Directory of Open Access Journals (Sweden)

Feifei Wang

2016-04-01

Full Text Available Abstract Background Epidemiological and experimental studies have suggested that exposure to particulate air pollution may promote progression of atherosclerosis. Methods In the present study, the characteristics and trends of the research field of particulate matter (PM and atherosclerosis were analyzed using bibliometric indicators. Bibliometric analysis was based on original papers obtained from PubMed/MEDLINE search results (from 1973 to 2014 using Medical Subject Headings (MeSH terms. A fully-detailed search strategy was employed, and articles were imported into the Thomson Data Analyzer (TDA software. Results The visualizing network of the collaborative researchers was analyzed by Ucinet 6 software. Main research topics and future focuses were explored by co-word and cluster analysis. The characteristics of these research articles were summarized. The number of published articles has increased from five for the period 1973–1978 to 89 for the period 2009–2014. Tobacco smoke pollution, smoke and air PM were the most studied targets in this research field. Coronary disease was the top health outcome posed by PM exposure. The aorta and endothelium vascular were the principal locations of atherosclerotic lesions, which were enhanced by PM exposure. Oxidative stress and inflammation were of special concern in the current mechanistic research system. The top high-frequency MeSH terms were clustered, and four popular topics were further presented. Conclusion Based on the quantitative analysis of bibliographic information and MeSH terms, we were able to define the study characteristics and popular topics in the field of PM and atherosclerosis. Our analysis would provide a comprehensive background reference for researchers in this field of study.

Latina girls of Puerto Rican origin who are successful in science and mathematics high school courses

Science.gov (United States)

Oquendo-Rodriguez, Aida L.

Professions and careers related to science and mathematics lack representation of minorities. Within these underrepresented minority populations there is no other group more affected than Latina women and girls. Women in general, are still underrepresented in many areas of our society. While women's roles are changing in today's society, most changes encourage the participation of more White/Anglo women in traditionally male roles. Latina women are still more disadvantaged than White women. There is no doubt that education is significant in increasing the participation of minorities in the fields of science and mathematics, especially for minority girls (Oakes, 1990; Rodriguez, 1993). This study explored the interests, life experiences, characteristics and motivations of Latina girls of Puerto Rican origin who are successful in science and mathematics high school courses. The study identifies factors that can influence the interest of Latina girls of Puerto Rican origin in science and mathematics career choices. This research is significant and relevant to educators and policy makers, especially to science and mathematics educators. The research is primarily descriptive and exploratory. It explores the social characteristics of Latina girls and professional women who have been successful in science and mathematics high school courses. The research offers the reader a visit to the participants' homes with descriptions and the opportunity to explore the thoughts and life experiences of Latina girls, their mothers and young Latina professionals of Puerto Rican origin. This research reveals the common characteristics of successful students found in the Latina girls of Puerto Rican origin who where interviewed. Creating a portrait of Latina girls of Puerto Rican origin who are successful in science and mathematics high school courses in one of the school districts of western Massachusetts. The research findings reveal that teacher relationships, family expectations

The next step for stress research in primates: To identify relationships between glucocorticoid secretion and fitness.

Science.gov (United States)

Beehner, Jacinta C; Bergman, Thore J

2017-05-01

Glucocorticoids are hormones that mediate the energetic demands that accompany environmental challenges. It is therefore not surprising that these metabolic hormones have come to dominate endocrine research on the health and fitness of wild populations. Yet, several problems have been identified in the vertebrate research that also apply to the non-human primate research. First, glucocorticoids should not be used as a proxy for fitness (unless a link has previously been established between glucocorticoids and fitness for a particular population). Second, stress research in behavioral ecology has been overly focused on "chronic stress" despite little evidence that chronic stress hampers fitness in wild animals. Third, research effort has been disproportionately focused on the causes of glucocorticoid variation rather than the fitness consequences. With these problems in mind, we have three objectives for this review. We describe the conceptual framework behind the "stress concept", emphasizing that high glucocorticoids do not necessarily indicate a stress response, and that a stress response does not necessarily indicate an animal is in poor health. Then, we conduct a comprehensive review of all studies on "stress" in wild primates, including any study that examined environmental factors, the stress response, and/or fitness (or proxies for fitness). Remarkably, not a single primate study establishes a connection between all three. Finally, we provide several recommendations for future research in the field of primate behavioral endocrinology, primarily the need to move beyond identifying the factors that cause glucocorticoid secretion to additionally focus on the relationship between glucocorticoids and fitness. We believe that this is an important next step for research on stress physiology in primates. Copyright © 2017 Elsevier Inc. All rights reserved.

Generational Variations in Mexican-Origin Intermarriage

OpenAIRE

Cedillo, Rosalio

2015-01-01

This dissertation examines intermarriage across generations of the Mexican-origin population in order to better understand how this population is incorporating in U.S. society, and looks at parental migration status and parental nativity as factors that may impede or facilitate intermarriage incorporation. Using data from the Immigration and Intergenerational Mobility in Metropolitan Los Angeles (IIMMLA) survey the research shows that: the majority of intermarriages among the Mexican-origin ...

Does a research article's country of origin affect perception of its quality and relevance? A national trial of US public health researchers.

Science.gov (United States)

Harris, M; Macinko, J; Jimenez, G; Mahfoud, M; Anderson, C

2015-12-30

The source of research may influence one's interpretation of it in either negative or positive ways, however, there are no robust experiments to determine how source impacts on one's judgment of the research article. We determine the impact of source on respondents' assessment of the quality and relevance of selected research abstracts. Web-based survey design using four healthcare research abstracts previously published and included in Cochrane Reviews. All Council on the Education of Public Health-accredited Schools and Programmes of Public Health in the USA. 899 core faculty members (full, associate and assistant professors) Each of the four abstracts appeared with a high-income source half of the time, and low-income source half of the time. Participants each reviewed the same four abstracts, but were randomly allocated to receive two abstracts with high-income source, and two abstracts with low-income source, allowing for within-abstract comparison of quality and relevance Within-abstract comparison of participants' rating scores on two measures--strength of the evidence, and likelihood of referral to a peer (1-10 rating scale). OR was calculated using a generalised ordered logit model adjusting for sociodemographic covariates. Participants who received high income country source abstracts were equal in all known characteristics to the participants who received the abstracts with low income country sources. For one of the four abstracts (a randomised, controlled trial of a pharmaceutical intervention), likelihood of referral to a peer was greater if the source was a high income country (OR 1.28, 1.02 to 1.62, pincome source in their rating of research abstracts. More research may be needed to explore how the origin of a research article may lead to stereotype activation and application in research evaluation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

An integrated approach to identify the origin of PM10 exceedances.

Science.gov (United States)

Amodio, M; Andriani, E; de Gennaro, G; Demarinis Loiotile, A; Di Gilio, A; Placentino, M C

2012-09-01

This study was aimed to the development of an integrated approach for the characterization of particulate matter (PM) pollution events in the South of Italy. PM(10) and PM(2.5) daily samples were collected from June to November 2008 at an urban background site located in Bari (Puglia Region, South of Italy). Meteorological data, particle size distributions and atmospheric dispersion conditions were also monitored in order to provide information concerning the different features of PM sources. The collected data allowed suggesting four indicators to characterize different PM(10) exceedances. PM(2.5)/PM(10) ratio, natural radioactivity, aerosol maps and back-trajectory analysis and particle distributions were considered in order to evaluate the contribution of local anthropogenic sources and to determine the different origins of intrusive air mass coming from long-range transport, such as African dust outbreaks and aerosol particles from Central and Eastern Europe. The obtained results were confirmed by applying principal component analysis to the number particle concentration dataset and by the chemical characterization of the samples (PM(10) and PM(2.5)). The integrated approach for PM study suggested in this paper can be useful to support the air quality managers for the development of cost-effective control strategies and the application of more suitable risk management approaches.

Identifying the Gifted Child Humorist.

Science.gov (United States)

Fern, Tami L.

1991-01-01

This study attempted to identify gifted child humorists among 1,204 children in grades 3-6. Final identification of 13 gifted child humorists was determined through application of such criteria as funniness, originality, and exemplary performance or product. The influence of intelligence, development, social factors, sex differences, family…

Identifying the Gender Dimension in Research Content

Energy Technology Data Exchange (ETDEWEB)

Campbell, D.; Lalonde, B.St.L.; Tippett, C.; Archambault, E.; Callaert, J.; Mantouvalou, K.; Arora, L.

2016-07-01

Globally, there is an increasing interest in integrating the gender dimension in research content (GDRC). As a first step towards monitoring progress in this area, a new indicator measuring the proportion of a country’s scientific publications integrating a gender dimension in their subject matter was developed for the European Commission’s She Figures 2015 publication. This indicator is based on a keyword-based query covering both sex-related terms (biological characteristics of both women and men) and gender-related terms (social/cultural factors of both women and men). The final GDRC dataset consisted of some 212,600 distinct publications including a gender dimension in their research content. Findings suggest that integrating a gender dimension into research content is relatively rare. Unsurprisingly, it was less common for scientific articles in the fields of agricultural sciences, engineering and technology, and natural sciences to do so, and more common in the social sciences. (Author)

Identifying Discrimination at Work: The Use of Field Experiments.

Science.gov (United States)

Pager, Devah; Western, Bruce

2012-06-01

Antidiscrimination law offers protection to workers who have been treated unfairly on the basis of their race, gender, religion, or national origin. In order for these protections to be invoked, however, potential plaintiffs must be aware of and able to document discriminatory treatment. Given the subtlety of contemporary forms of discrimination, it is often difficult to identify discrimination when it has taken place. The methodology of field experiments offers one approach to measuring and detecting hiring discrimination, providing direct observation of discrimination in real-world settings. In this article, we discuss the findings of two recent field experiments measuring racial discrimination in low wage labor markets. This research provides several relevant findings for researchers and those interested in civil rights enforcement: (1) it produces estimates of the rate of discrimination at the point of hire; (2) it yields evidence about the interactions associated with discrimination (many of which reveal the subtlety with which contemporary discrimination is practiced); and (3) it provides a vehicle for both research on and enforcement of antidiscrimination law.

Identifying knowledge gaps for gene drive research to control invasive animal species: The next CRISPR step

Directory of Open Access Journals (Sweden)

Dorian Moro

2018-01-01

Full Text Available Invasive animals have been linked to the extinctions of native wildlife, and to significant agricultural financial losses or impacts. Current approaches to control invasive species require ongoing resources and management over large geographic scales, and often result in the short-term suppression of populations. New and innovative approaches are warranted. Recently, the RNA guided gene drive system based on CRISPR/Cas9 is being proposed as a potential gene editing tool that could be used by wildlife managers as a non-lethal addition or alternative to help reduce pest animal populations. While regulatory control and social acceptance are crucial issues that must be addressed, there is an opportunity now to identify the knowledge and research gaps that exist for some important invasive species. Here we systematically determine the knowledge gaps for pest species for which gene drives could potentially be applied. We apply a conceptual ecological risk framework within the gene drive context within an Australian environment to identify key requirements for undertaking work on seven exemplar invasive species in Australia. This framework allows an evaluation of the potential research on an invasive species of interest and within a gene drive and risk context. We consider the currently available biological, genetic and ecological information for the house mouse, European red fox, feral cat, European rabbit, cane toad, black rat and European starling to evaluate knowledge gaps and identify candidate species for future research. We discuss these findings in the context of future thematic areas of research worth pursuing in preparation for a more formal assessment of the use of gene drives as a novel strategy for the control of these and other invasive species. Keywords: Invasive species, Gene drive, CRISPR, Pest management, Islands

Persistent Identifiers for Field Deployments: A Missing Link in the Provenance Chain

Science.gov (United States)

Arko, R. A.; Ji, P.; Fils, D.; Shepherd, A.; Chandler, C. L.; Lehnert, K.

2016-12-01

Research in the geosciences is characterized by a wide range of complex and costly field deployments including oceanographic cruises, submersible dives, drilling expeditions, seismic networks, geodetic campaigns, moored arrays, aircraft flights, and satellite missions. Each deployment typically produces a mix of sensor and sample data, spanning a period from hours to decades, that ultimately yields a long tail of post-field products and publications. Publishing persistent, citable identifiers for field deployments will facilitate 1) preservation and reuse of the original field data, 2) reproducibility of the resulting publications, and 3) recognition for both the facilities that operate the platforms and the investigators who secure funding for the experiments. In the ocean domain, sharing unique identifiers for field deployments is a familiar practice. For example, the Biological and Chemical Oceanography Data Management Office (BCO-DMO) routinely links datasets to cruise identifiers published by the Rolling Deck to Repository (R2R) program. In recent years, facilities have started to publish formal/persistent identifiers, typically Digital Object Identifiers (DOIs), for field deployments including seismic networks, oceanographic cruises, and moored arrays. For example, the EarthChem Library (ECL) publishes a DOI for each dataset which, if it derived from an oceanographic research cruise on a US vessel, is linked to a DOI for the cruise published by R2R. Work is underway to create similar links for the IODP JOIDES Resolution Science Operator (JRSO) and the Continental Scientific Drilling Coordination Office (CSDCO). We present results and lessons learned including a draft schema for publishing field deployments as DataCite DOI records; current practice for linking these DOIs with related identifiers such as Open Researcher and Contributor IDs (ORCIDs), Open Funder Registry (OFR) codes, and International Geo Sample Numbers (IGSNs); and consideration of other

Algerian medical teachers' research output and its determinants during the 2000-2009 decade.

Science.gov (United States)

Bezzaoucha, A; Atif, M L; Bouamra, A; El Kebboub, A; Benzerga, M; Ben Abdelaziz, A; Soulimane, A; Ladner, J; Borgès Da Silva, G; Meguenni, K; Quessar, A; Heroual, N; Bouguizi, A; Boussouf, N; Makhlouf, F; Lamdjadani, N; Tibiche, A; Abbassene, S; Regagba, D; Benameur, M

2014-02-01

Publications are the primary output of scientific research. We conducted a national study to quantify Algerian medical teachers' research output and identify its determinants during the 2000-2009 decade. The American Medline database and the French Pascal database were used. A publication was eligible only if the lead author was an Algerian medical teacher (in medicine, pharmacy, or dentistry) working in Algeria. The same questionnaire was completed by cases (teachers who were first authors of an original article during the study period) and randomly selected controls. Logistic regression analysis was used to identify factors related to research output. A total of 79 original articles (42.2% of publications) were retrieved, a quarter of which were listed in Pascal alone. The publication rate was 2.6 original articles per 1000 teachers per year. The journals that published these original articles had a median impact factor of 0.83. The ability to publish an original article was 4.3 times higher if the teacher had undergone training in biostatistics and/or epidemiology (adjusted odds ratio [aOR]=4.31, 95% confidence interval [CI]: 1.79-10.38). A promotion evaluation grid that did not encourage writing (aOR=3.44, 95% CI: 1.42-8.33), a doctoral thesis, seniority, foreign collaboration, and English language proficiency were found to be associated with publication output. Algerian medical teachers' research output was particularly low. Replacing the current promotion grid with a grid that promotes writing, developing abilities to read and write articles and developing English language proficiency are likely to improve this situation. Copyright © 2014. Published by Elsevier Masson SAS.

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Abstract. The present study was performed to screen antiba scavenging efficacy of leaf and flower extract. Antibacterial and antifungal activity was evaluated poisoned food technique respectively. Radical scave by DPPH free radical scavenging assay. Overall, L displayed stronger antibacterial and antifungal activity.

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2015-03-17

Mar 17, 2015 ... absence of carotenoids pigments (Eriksson et al., 2008). Yellow skin color is the result of the expression of carotenoid pigments in the skins of birds (Smyth, 1990) and according to Eriksson et al. (2008), it is generally considered to be associated with the individual's adaptive fitness reflecting its nutritional ...

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2009-09-17

Sep 17, 2009 ... agriculture systems in Edo state, Nigeria and char ... were inferred as different varieties of the species of th ... tate, Nigeria and characterize them using molecular marker ... Article Information ... The development of Polymerase Chain Reaction (PCR) ... Quarters, University of Benin Teaching Hospital.

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assland, wetland and bare land) using remote sensing-GIS ... the land and the environment r and Turner, 1998). .... According to the agro-climatic classification of Ethiopia ... The image of the 1986 TM has found with cloud ..... agriculture over steep slopes results in a disastrous effect ..... Transition Potential Modeling for.

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said that teacher's support and commitment, peer lea as peer ... Bahir Dar University (BDU) English majoring students' ... f English major students at BDU in the 2013/14 Academic Year ... continues his/her leadership ... teachers, to share experiences both in aca ... philosophies (theories), PLL maintains the principle that.

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Abrasive jet machining (AJM) is a micromachining p the work piece by the erosion effect of a high speed ... INTRODUCTION. Abrasive water jets, namely water jets con abrasive particles, have a considerable niche .... cleaning, such as removal of smudges from antique documents, is also possible with AJM. Circular Nozzle.

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2015-03-08

Mar 8, 2015 ... variables using ordinary least squares or tobit regression. This approach has ... The Stochastic Frontier Analysis (SFA) is an analytical approach that .... discussing about parameter estimates of the models, tests of hypotheses ...

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activation energy (kJ/mol), R is the ideal gas constant. (8.314 J/mol. K), T is the actual temperature (K), and t is the time (min). Kinetic parameters for ascorbic acid degradation were estimated by a common two-step linear regression method (Esteve et al. 1998, 1999). In the first regression, the logarithm of the values of ...

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s to find out how teachers of EFL monitor their students' group ... Group management ... activity into the classroom that best suits the learners' ... that learning under stress and negative attitude is often ... relationships means a learner knows he/she can turn to ..... give the group tasks in the assignment form than dealing.

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2015-03-15

Mar 15, 2015 ... powder were evaluated against the maize weevil in n laid out in a randomized complete ..... diatomaceous earth with plant extracts, insecticides and ... commercial neem product Azal-T/S (1 gm kg-1) resulted in higher mortality ...

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financial, emotional, personal and social costs fo families and twins themselves. It accounts for a. 10% of perinatal mortality (Dera et al., 2007; Gess. 2007 and Abasiattai et al., 2010). A number of unique complications develop i pregnancies. They include conjoined twinning, t twin transfusion syndrome (TTTS), growth discor.

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51.5 abcdefg 85.35 bcd. 3.25. 9.0 d. 20. ETBW 7161 79.0 fghijk. 132.0 bcde 48.5 bcdefg. 84.20 bcdef. 2.8. 10.0 c. 21. ETBW 7191 75.5 kl. 128.5 def. 52.5 abcdef. 81.70 defghij 2.85. 10.0 c. 22. ETBW 7199 83.5 cdefg. 131.5 bcdef 48.0 bcdefg. 83.30 cdefg. 3.10. 11.0 a. 23. ETBW 7182 78.0 ghijkl. 128.5 def. 50.5 abcdefg ...

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Official International Journal of Wollega University, Ethiopia ..... to combat drug resistance. It has bee extracts and purified components from promising ..... American. Journal of Plant Sciences 2: 841-846. Upreti, D.K., Nayaka, S. (2008).

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estimations. Malt extract broth inoculated with pure cultures was incubated up to 14 days. Out of 30 fungi tested for lignolytic activity eighteen showed positive and .... DNA was diluted in 50 µl TE buffer. The genomic DNA of the macro fungi were then subjected to PCR to amplify the ITS regions of the nuclear ribosomal DNA ...

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Sesame (Sesamum indicum L.) is an important production and it ranks first in total production fro determine the extent of genetic variability, heritability populations from Ethiopia. The populations were gro. Arjo District, East Wollega Zone, Ethiopia during 20 agronomic traits and analyzed using SAS software v were highly ...

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thermal stability, high permeability, high electrical res ... Structural and Magnetic Properties of Nanostructured Co .... means of an interfacial reaction. ... n Figure 3 as E = 11.6 kJ/mol. the grain grows primarily by tion. It also shows that growth.

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social networks, bonding similar people and b between diverse ... Abstract e of social capital in rice production in Kwara State, Nigeria. ... bind the members of human networks and ..... extension officers to promote social capital in Japanese.

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Adoption of wheat row planting is one of the farming practices ld in the country. .... Wheat is a major crop and it accounts for 42% of the total cereal area ... the first stage of probability sampling, a list of major wheat producing .... Variables. Measurement ..... company. Krejcie, R.V. and Morgan, D.W. (1970). Determing sample.

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In tropical climate, castor leaves loss considerable ... are parts of tropical climate and castor leaf moisture evapo-transformation is very high and changes the leaf to unpalatable ..... leaf in water also removes the dust and dirt present on the.

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2015-03-15

Mar 15, 2015 ... heating), inert dusts (wood ash, sand and Silic varietal tolerance, mixing with small cereal grains s ... ptions such as physical (solar ash, sand and SilicoSec), th small cereal grains such as ..... agreement with numerous works on combinations of different materials against storage pests. For example,.

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1270.04cm-1 are attributed to an olefinic system and C-O stretching vibration of an ester moiety, respectively. Furthermore, the IR absorptions at 2922.92cm-1 and. 3010cm-1 suggest sp3. C-H stretching and sp2. C-H stretching vibrations, respectively. The UV spectrum showed characteristic absorption bands for ester ...

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uces important fluctuations in crop yields, uncertainties, and food e study has focused to ... e main market, distance to access agricultural extension, access cess to new cultivars .... Clearly, in Ethiopia, rice is among the target commodities that ...

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MATERIALS AND METHODS. Study Area and ... establish replicated planting materials at each home .... content (Sankaram, 1996), organic carbon content, available ..... and measure most of the elements essential to plant nutrition as .... manipulate cocoyam canopy architecture, leaf production, planting .... Application of.

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(NO) and cause anxious behavior in rodents (Sevg. 2006). .... sial results for the effects of ants on NOS activity but the actions .... Behavioral testing was performed carefully in a stepwise manner i.e. mice in each group were subjected to three tests (Dunn et al., 2005): (a) Tail Suspension Test; then a 6 min rest in home cage ...

Identifying Obstacles and Research Gaps of Telemedicine Projects: Approach for a State-of-the-Art Analysis.

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Harst, Lorenz; Timpel, Patrick; Otto, Lena; Wollschlaeger, Bastian; Richter, Peggy; Schlieter, Hannes

2018-01-01

This paper presents an approach for an evaluation of finished telemedicine projects using qualitative methods. Telemedicine applications are said to improve the performance of health care systems. While there are countless telemedicine projects, the vast majority never makes the threshold from testing to implementation and diffusion. Projects were collected from German project databases in the area of telemedicine following systematically developed criteria. In a testing phase, ten projects were subject to a qualitative content analysis to identify limitations, need for further research, and lessons learned. Using Mayring's method of inductive category development, six categories of possible future research were derived. Thus, the proposed method is an important contribution to diffusion and translation research regarding telemedicine, as it is applicable to a systematic research of databases.

Analytical Chemistry Section Chemistry Research Group, Winfrith. Report for 1982 and 1983

International Nuclear Information System (INIS)

Amey, M.D.H.; Capp, P.D.; James, H.

1984-01-01

This report reviews the principal activities of the Analytical Chemistry Section of Chemistry Research Group, Winfrith, during 1982 and 1983. The objectives of the report are to outline the range of chemical analysis support services available at Winfrith, indicate the research areas from which samples currently originate, and identify instrumental techniques where significant updating has occurred. (author)

40 CFR 52.1037 - Original identification of plan section.

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2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Original identification of plan section... identification of plan section. (a) This section identifies the original “Air Implementation Plan for the State...), and conditions 12(A), 12(C), (13), (14) and (15) for Tree Free Fiber Company, LLC, (formerly Statler...

Characterization of size, composition and origins of dust in fusion devices. Summary report of the 1. research coordination meeting

International Nuclear Information System (INIS)

Clark, R.E.H.

2009-03-01

Nine experts on dust formation and their physical and behavioural characteristics attended the first Research Coordination Meeting (RCM) on Characterization of Size, Composition and Origins of Dust in Fusion Devices held at IAEA Headquarters on 10-12 December 2008. Participants summarized recent relevant developments related to dust in fusion devices. The specific objectives of the CRP and a detailed work plan were formulated. Discussions, conclusions and recommendations of the RCM are briefly described in this report. (author)

Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.

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Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J; Strickland, Judy; Bell, Shannon; Bhhatarai, Barun; Blaauboer, Bas; Casey, Warren; Dorman, David; Forsby, Anna; Garcia-Reyero, Natàlia; Gehen, Sean; Graepel, Rabea; Hotchkiss, Jon; Lowit, Anna; Matheson, Joanna; Reaves, Elissa; Scarano, Louis; Sprankle, Catherine; Tunkel, Jay; Wilson, Dan; Xia, Menghang; Zhu, Hao; Allen, David

2017-06-01

Acute systemic toxicity testing provides the basis for hazard labeling and risk management of chemicals. A number of international efforts have been directed at identifying non-animal alternatives for in vivo acute systemic toxicity tests. A September 2015 workshop, Alternative Approaches for Identifying Acute Systemic Toxicity: Moving from Research to Regulatory Testing, reviewed the state-of-the-science of non-animal alternatives for this testing and explored ways to facilitate implementation of alternatives. Workshop attendees included representatives from international regulatory agencies, academia, nongovernmental organizations, and industry. Resources identified as necessary for meaningful progress in implementing alternatives included compiling and making available high-quality reference data, training on use and interpretation of in vitro and in silico approaches, and global harmonization of testing requirements. Attendees particularly noted the need to characterize variability in reference data to evaluate new approaches. They also noted the importance of understanding the mechanisms of acute toxicity, which could be facilitated by the development of adverse outcome pathways. Workshop breakout groups explored different approaches to reducing or replacing animal use for acute toxicity testing, with each group crafting a roadmap and strategy to accomplish near-term progress. The workshop steering committee has organized efforts to implement the recommendations of the workshop participants. Copyright © 2017 Elsevier Ltd. All rights reserved.

Promoting Original Scientific Research and Teacher Training Through a High School Science Research Program: A Five Year Retrospective and Analysis of the Impact on Mentored 8th Grade Geoscience Students and the Mentors Themselves

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Danch, J. M.

2015-12-01

In 2010 a group of 8th grade geoscience students participated in an extracurricular activity allowing them to conduct original scientific research while being mentored by students enrolled in a 3 - year high school Science Research program. Upon entering high school the mentored students themselves enrolled in the Science Research program and continued for 4 years, culminating with their participation in Science Research 4. This allowed them to continue conducting original scientific research, act as mentors to 8th grade geoscience students and to provide teacher training for both middle and high school teachers conducting inquiry-based science lessons. Of the 7 Science Research 4 students participating since 2010, 100% plan on majoring or minoring in a STEM - related field in college and their individual research projects have been been granted over 70 different awards and honors in science fair and symposia including a 3rd and 4th place category awards at two different international science fairs - the International Sustainable Energy Engineering and Environment Project (iSWEEP) and the International Science and Engineering Fair (ISEF). Science Research 4 students developed and conducted a Society for Science and the Public affiliated science fair for middle school students enrolled in an 8th grade honors geoscience program allowing over 100 students from 5 middle schools to present their research and be judged by STEM professionals. Students with research judged in the top 10% were nominated for participation in the National Broadcom MASTERS program which they successfully entered upon further mentoring from the Science Research 4 students. 8th grade enrollment in the Science Research program for 2015 increased by almost 50% with feedback from students, parents and teachers indicating that the mentorship and participation in the 8th grade science fair were factors in increasing interest in continuing authentic scientific research in high school.

Mechanisms of change in psychotherapy for depression: An empirical update and evaluation of research aimed at identifying psychological mediators.

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Lemmens, Lotte H J M; Müller, Viola N L S; Arntz, Arnoud; Huibers, Marcus J H

2016-12-01

We present a systematic empirical update and critical evaluation of the current status of research aimed at identifying a variety of psychological mediators in various forms of psychotherapy for depression. We summarize study characteristics and results of 35 relevant studies, and discuss the extent to which these studies meet several important requirements for mechanism research. Our review indicates that in spite of increased attention for the topic, advances in theoretical consensus about necessities for mechanism research, and sophistication of study designs, research in this field is still heterogeneous and unsatisfactory in methodological respect. Probably the biggest challenge in the field is demonstrating the causal relation between change in the mediator and change in depressive symptoms. The field would benefit from a further refinement of research methods to identify processes of therapeutic change. Recommendations for future research are discussed. However, even in the most optimal research designs, explaining psychotherapeutic change remains a challenge. Psychotherapy is a multi-dimensional phenomenon that might work through interplay of multiple mechanisms at several levels. As a result, it might be too complex to be explained in relatively simple causal models of psychological change. Copyright © 2016 Elsevier Ltd. All rights reserved.

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review.

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Stuart G Nicholls

Full Text Available To date there is no established consensus of assessment criteria for evaluating research ethics review.We conducted a scoping review of empirical research assessing ethics review processes in order to identify common elements assessed, research foci, and research gaps to aid in the development of assessment criteria. Electronic searches of Ovid Medline, PsychInfo, and the Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED, were conducted. After de-duplication, 4234 titles and abstracts were reviewed. Altogether 4036 articles were excluded following screening of titles, abstracts and full text. A total of 198 articles included for final data extraction.Few studies originated from outside North America and Europe. No study reported using an underlying theory or framework of quality/effectiveness to guide study design or analyses. We did not identify any studies that had involved a controlled trial--randomised or otherwise--of ethics review procedures or processes. Studies varied substantially with respect to outcomes assessed, although tended to focus on structure and timeliness of ethics review.Our findings indicate a lack of consensus on appropriate assessment criteria, exemplified by the varied study outcomes identified, but also a fragmented body of research. To date research has been largely quantitative, with little attention given to stakeholder experiences, and is largely cross sectional. A lack of longitudinal research to date precludes analyses of change or assessment of quality improvement in ethics review.

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review

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Nicholls, Stuart G.; Hayes, Tavis P.; Brehaut, Jamie C.; McDonald, Michael; Weijer, Charles; Saginur, Raphael; Fergusson, Dean

2015-01-01

Background To date there is no established consensus of assessment criteria for evaluating research ethics review. Methods We conducted a scoping review of empirical research assessing ethics review processes in order to identify common elements assessed, research foci, and research gaps to aid in the development of assessment criteria. Electronic searches of Ovid Medline, PsychInfo, and the Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED, were conducted. After de-duplication, 4234 titles and abstracts were reviewed. Altogether 4036 articles were excluded following screening of titles, abstracts and full text. A total of 198 articles included for final data extraction. Results Few studies originated from outside North America and Europe. No study reported using an underlying theory or framework of quality/effectiveness to guide study design or analyses. We did not identify any studies that had involved a controlled trial - randomised or otherwise – of ethics review procedures or processes. Studies varied substantially with respect to outcomes assessed, although tended to focus on structure and timeliness of ethics review. Discussion Our findings indicate a lack of consensus on appropriate assessment criteria, exemplified by the varied study outcomes identified, but also a fragmented body of research. To date research has been largely quantitative, with little attention given to stakeholder experiences, and is largely cross sectional. A lack of longitudinal research to date precludes analyses of change or assessment of quality improvement in ethics review. PMID:26225553

Computed Tomography Image Origin Identification Based on Original Sensor Pattern Noise and 3-D Image Reconstruction Algorithm Footprints.

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Duan, Yuping; Bouslimi, Dalel; Yang, Guanyu; Shu, Huazhong; Coatrieux, Gouenou

2017-07-01

In this paper, we focus on the "blind" identification of the computed tomography (CT) scanner that has produced a CT image. To do so, we propose a set of noise features derived from the image chain acquisition and which can be used as CT-scanner footprint. Basically, we propose two approaches. The first one aims at identifying a CT scanner based on an original sensor pattern noise (OSPN) that is intrinsic to the X-ray detectors. The second one identifies an acquisition system based on the way this noise is modified by its three-dimensional (3-D) image reconstruction algorithm. As these reconstruction algorithms are manufacturer dependent and kept secret, our features are used as input to train a support vector machine (SVM) based classifier to discriminate acquisition systems. Experiments conducted on images issued from 15 different CT-scanner models of 4 distinct manufacturers demonstrate that our system identifies the origin of one CT image with a detection rate of at least 94% and that it achieves better performance than sensor pattern noise (SPN) based strategy proposed for general public camera devices.

Original geochemical types and epigenetic alteration of rocks in prospecting target stratum for uranium deposit in the southeast of Songliao basin

International Nuclear Information System (INIS)

Lin Jinrong; Tian Hua; Dong Wenming; Xia Yuliang; Qi Daneng; Yao Shancong; Zheng Jiwei

2009-01-01

By comprehensive analysis on informations of regional geology and evaluating drillhole works of uranium resources in the southeast of Songliao basin, lithofacies-palaeogeography features, lithologies and sandbody characteristics of target layes in Quantou formation, Yaojia formation and Sifangtai formation have been basically found out. By research on geochemical environment of rocks in target layez, types of original geochemistry and epigenetic alteration have been identified and classified. The types of original geochemistry have been divided into types of original oxidation and original reduction, and the types of epigenetic alteration have been divided into types of reduction by oil-gas and coalbed gas and epigenetic oxidation. By comparative study on mineral and chemical characteristics of original geochemistry and epigenetic oxidation, identification marks for oil-gas and coalbed gas reduced epigenetic oxidation have been proposed. It is proposed that uranium was strongly pre-concentrated in original sandstone that bearing carboniferous matter, and reduction by oil-gas and coalbed gas made uranium superimpose and concentrate in alterated rocks. (authors)

Trends in Type of Original Psoriasis Publications by Decade, 1960 to 2010.

Science.gov (United States)

Sako, Eric; Famenini, Shannon; Wu, Jashin J

2016-01-01

Research investigating psoriasis has spanned decades, and as our understanding of the disease has evolved, the focus of publications has changed. We sought to characterize the trends in original psoriasis-related research from 1960 to 2010 chronologically by decade. A literature review was performed using the keyword psoriasis in the MEDLINE database. All original psoriasis-related articles published at the beginning of each decade were searched and categorized by study type and topic. Number of articles per topic. A total of 869 original psoriasis-related articles were found. The number of publications increased 18 fold over 5 decades. The immunology and pathogenesis of psoriasis was the most frequently researched topic (36%), and retrospective studies were the most common study type (37%). Recent highly published topics included biologic therapy, genetics, and psoriasis-associated cardiovascular disease. Original psoriasis-related publications have grown substantially since 1960. Basic science research into the immunology and pathogenesis has been and continues to be the mainstay of psoriasis research. Recent research trends suggest the focus has expanded to topics such as psoriasis-associated cardiovascular disease, genetics, and biologic therapy.

The origins of originality: the neural bases of creative thinking and originality.

Science.gov (United States)

Shamay-Tsoory, S G; Adler, N; Aharon-Peretz, J; Perry, D; Mayseless, N

2011-01-01

Although creativity has been related to prefrontal activity, recent neurological case studies postulate that patients who have left frontal and temporal degeneration involving deterioration of language abilities may actually develop de novo artistic abilities. In this study, we propose a neural and cognitive model according to which a balance between the two hemispheres affects a major aspect of creative cognition, namely, originality. In order to examine the neural basis of originality, that is, the ability to produce statistically infrequent ideas, patients with localized lesions in the medial prefrontal cortex (mPFC), inferior frontal gyrus (IFG), and posterior parietal and temporal cortex (PC), were assessed by two tasks involving divergent thinking and originality. Results indicate that lesions in the mPFC involved the most profound impairment in originality. Furthermore, precise anatomical mapping of lesions indicated that while the extent of lesion in the right mPFC was associated with impaired originality, lesions in the left PC were associated with somewhat elevated levels of originality. A positive correlation between creativity scores and left PC lesions indicated that the larger the lesion is in this area the greater the originality. On the other hand, a negative correlation was observed between originality scores and lesions in the right mPFC. It is concluded that the right mPFC is part of a right fronto-parietal network which is responsible for producing original ideas. It is possible that more linear cognitive processing such as language, mediated by left hemisphere structures interferes with creative cognition. Therefore, lesions in the left hemisphere may be associated with elevated levels of originality. Copyright © 2010 Elsevier Ltd. All rights reserved.

Monochromatic and identifiable photons used in photonuclear research

International Nuclear Information System (INIS)

Beil, Hans; Bergere, Roland.

1980-07-01

A general overview is given of the most common experimental procedures for the production and utilisation of monochromatic and (or) identifiable photon probes actually operational in 1979. Their basic characteristics, merits and drawbacks, together with their respective major domains of experimental physics to which they are usually applied, are also investigated. Methods for producing such monochromatic and (or) identifiable photon probes, with a continuously variable energy from a few MeV up till about 180 GeV, are treated in some detail. Some of the most promising future trends in the ulterior development of such electromagnetic probes are also mentioned

ORIGIN: metal creation and evolution from the cosmic dawn

NARCIS (Netherlands)

den Herder, J.W.; Piro, L.; Ohashi, T.; Kouveliotou, C.; Hartmann, D.H.; Kaastra, J.S.; Amati, L.; Andersen, M.I.; Arnaud, M.; Atteia, J.-L.; Bandler, S.; Barbera, M.; Barcons, X.; Barthelmy, S.; Basa, S.; Basso, S.; de Boer, M.; Branchini, E.; Branduardi-Raymont, G.; Borgani, S.; Boyarsky, A.; Brunetti, G.; Budtz-Jorgensen, C.; Burrows, D.; Butler, N.; Campana, S.; Caroli, E.; Ceballos, M.; Christensen, F.; Churazov, E.; Comastri, A.; Colasanti, L.; Cole, R.; Content, R.; Corsi, A.; Costantini, E.; Conconi, P.; Cusumano, G.; de Plaa, J.; De Rosa, A.; Del Santo, M.; Di Cosimo, S.; De Pasquale, M.; Doriese, R.; Ettori, S.; Evans, P.; Ezoe, Y.; Ferrari, L.; Finger, H.; Figueroa-Feliciano, T.; Friedrich, P.; Fujimoto, R.; Furuzawa, A.; Fynbo, J.; Gatti, F.; Galeazzi, M.; Gehrels, N.; Gendre, B.; Ghirlanda, G.; Ghisellini, G.; Gilfanov, M.; Giommi, P.; Girardi, M.; Grindlay, J.; Cocchi, M.; Godet, O.; Guedel, M.; Haardt, F.; Hartog, R.; Hepburn, I.; Hermsen, W.; Hjorth, J.; Hoekstra, H.; Holland, A.; Hornstrup, A.; van der Horst, A.; Hoshino, A.; in 't Zand, J.; Irwin, K.; Ishisaki, Y.; Jonker, P.; Kitayama, T.; Kawahara, H.; Kawai, N.; Kelley, R.; Kilbourne, C.; de Korte, P.; Kusenko, A.; Kuvvetli, I.; Labanti, M.; Macculi, C.; Maiolino, R.; Mas Hesse, M.; Matsushita, K.; Mazzotta, P.; McCammon, D.; Méndez, M.; Mignani, R.; Mineo, T.; Mitsuda, K.; Mushotzky, R.; Molendi, S.; Moscardini, L.; Natalucci, L.; Nicastro, F.; O'Brien, P.; Osborne, J.; Paerels, F.; Page, M.; Paltani, S.; Pedersen, K.; Perinati, E.; Ponman, T.; Pointecouteau, E.; Predehl, P.; Porter, S.; Rasmussen, A.; Rauw, G.; Röttgering, H.; Roncarelli, M.; Rosati, P.; Quadrini, E.; Ruchayskiy, O.; Salvaterra, R.; Sasaki, S.; Sato, K.; Savaglio, S.; Schaye, J.; Sciortino, S.; Shaposhnikov, M.; Sharples, R.; Shinozaki, K.; Spiga, D.; Sunyaev, R.; Suto, Y.; Takei, Y.; Tanvir, N.; Tashiro, M.; Tamura, T.; Tawara, Y.; Troja, E.; Tsujimoto, M.; Tsuru, T.; Ubertini, P.; Ullom, J.; Ursino, E.; Verbunt, F.; van de Voort, F.; Viel, M.; Wachter, S.; Watson, D.; Weisskopf, M.; Werner, N.; White, N.; Willingale, R.; Wijers, R.; Yamasaki, N.; Yoshikawa, K.; Zane, S.

2012-01-01

ORIGIN is a proposal for the M3 mission call of ESA aimed at the study of metal creation from the epoch of cosmic dawn. Using high-spectral resolution in the soft X-ray band, ORIGIN will be able to identify the physical conditions of all abundant elements between C and Ni to red-shifts of z = 10,

ORIGIN : Metal creation and evolution from the cosmic dawn

NARCIS (Netherlands)

den Herder, Jan-Willem; Piro, Luigi; Ohashi, Takaya; Kouveliotou, Chryssa; Hartmann, Dieter H.; Kaastra, Jelle S.; Amati, L.; Andersen, M. I.; Arnaud, M.; Attéia, J.-L.; Bandler, S.; Barbera, M.; Barcons, X.; Barthelmy, S.; Basa, S.; Basso, S.; Boer, M.; Branchini, E.; Branduardi-Raymont, G.; Borgani, S.; Boyarsky, A.; Brunetti, G.; Budtz-Jorgensen, C.; Burrows, D.; Butler, N.; Campana, S.; Caroli, E.; Ceballos, M.; Christensen, F.; Churazov, E.; Comastri, A.; Colasanti, L.; Cole, R.; Content, R.; Corsi, A.; Costantini, E.; Conconi, P.; Cusumano, G.; de Plaa, J.; De Rosa, A.; Del Santo, M.; Di Cosimo, S.; De Pasquale, M.; Doriese, R.; Ettori, S.; Evans, P.; Ezoe, Y.; Ferrari, L.; Finger, H.; Figueroa-Feliciano, T.; Friedrich, P.; Fujimoto, R.; Furuzawa, A.; Fynbo, J.; Gatti, F.; Galeazzi, M.; Gehrels, N.; Gendre, B.; Ghirlanda, G.; Ghisellini, G.; Gilfanov, M.; Giommi, P.; Girardi, M.; Grindlay, J.; Cocchi, M.; Godet, O.; Guedel, M.; Haardt, F.; den Hartog, R.; Hepburn, I.; Hermsen, W.; Hjorth, J.; Hoekstra, H.; Holland, A.; Hornstrup, A.; van der Horst, A.; Hoshino, A.; in't Zand, J.; Irwin, K.; Ishisaki, Y.; Jonker, P.; Kitayama, T.; Kawahara, H.; Kawai, N.; Kelley, R.; Kilbourne, C.; de Korte, P.; Kusenko, A.; Kuvvetli, I.; Labanti, M.; Macculi, C.; Maiolino, R.; Hesse, M. Mas; Matsushita, K.; Mazzotta, P.; McCammon, D.; Méndez, M.; Mignani, R.; Mineo, T.; Mitsuda, K.; Mushotzky, R.; Molendi, S.; Moscardini, L.; Natalucci, L.; Nicastro, F.; O'Brien, P.; Osborne, J.; Paerels, F.; Page, M.; Paltani, S.; Pedersen, K.; Perinati, E.; Ponman, T.; Pointecouteau, E.; Predehl, P.; Porter, S.; Rasmussen, A.; Rauw, G.; Röttgering, H.; Roncarelli, M.; Rosati, P.; Quadrini, E.; Ruchayskiy, O.; Salvaterra, R.; Sasaki, S.; Sato, K.; Savaglio, S.; Schaye, J.; Sciortino, S.; Shaposhnikov, M.; Sharples, R.; Shinozaki, K.; Spiga, D.; Sunyaev, R.; Suto, Y.; Takei, Y.; Tanvir, N.; Tashiro, M.; Tamura, T.; Tawara, Y.; Troja, E.; Tsujimoto, M.; Tsuru, T.; Ubertini, P.; Ullom, J.; Ursino, E.; Verbunt, F.; van de Voort, F.; Viel, M.; Wachter, S.; Watson, D.; Weisskopf, M.; Werner, N.; White, N.; Willingale, R.; Wijers, R.; Yamasaki, N.; Yoshikawa, K.; Zane, S.

2012-01-01

ORIGIN is a proposal for the M3 mission call of ESA aimed at the study of metal creation from the epoch of cosmic dawn. Using high-spectral resolution in the soft X-ray band, ORIGIN will be able to identify the physical conditions of all abundant elements between C and Ni to red-shifts of z = 10,

Consumers’ Knowledge about Product’s Country-of-Origin and Its Impact upon Sensorical Product Evaluation

OpenAIRE

Tina Vukasovic

2015-01-01

The aim of the research was to determine consumer perceptions of food products regarding the knowledge about the product’s origin and the potential impact on the sensorical evaluation of other product properties. The research results represent a deeper investigation of the impact of origin on consumer perceptions. An integrated approach to the research of impacts of product origin was chosen in order to form interlinks between knowledge about product origin and its other sen...

Identifying and Managing Engineering Design Requirements for Emerging Markets

DEFF Research Database (Denmark)

Li, Xuemeng

, especially for those companies originally from developed markets, to acquire an in-depth understanding of particular design requirements in emerging markets in order to adapt both company products and approaches in such contexts. Prior studies on the identification and management of design requirements have...... predominantly been conducted in the context of developed countries and relatively affluent markets. Emerging markets are distinct from developed markets in terms of numerous contextual factors, e.g., regulatory environments and competitive landscapes. These factors influence the requirement identification...... attention. There is a need for an overview of different perspectives in requirement identification for manufacturing companies and their corresponding assessments in the context of emerging markets. Therefore, this research project is motivated to 1) investigate the process of identifying and managing...

Secondary uses and the governance of de-identified data: Lessons from the human genome diversity panel

Directory of Open Access Journals (Sweden)

Lee Sandra S-J

2011-09-01

Full Text Available Abstract Background Recent changes to regulatory guidance in the US and Europe have complicated oversight of secondary research by rendering most uses of de-identified data exempt from human subjects oversight. To identify the implications of such guidelines for harms to participants and communities, this paper explores the secondary uses of one de-identified DNA sample collection with limited oversight: the Human Genome Diversity Project (HGDP-Centre d'Etude du Polymorphisme Humain, Fondation Jean Dausset (CEPH Human Genome Diversity Panel. Methods Using a combination of keyword and cited reference search, we identified English-language scientific articles published between 2002 and 2009 that reported analysis of HGDP Diversity Panel samples and/or data. We then reviewed each article to identify the specific research use to which the samples and/or data was applied. Secondary uses were categorized according to the type and kind of research supported by the collection. Results A wide variety of secondary uses were identified from 148 peer-reviewed articles. While the vast majority of these uses were consistent with the original intent of the collection, a minority of published reports described research whose primary findings could be regarded as controversial, objectionable, or potentially stigmatizing in their interpretation. Conclusions We conclude that potential risks to participants and communities cannot be wholly eliminated by anonymization of individual data and suggest that explicit review of proposed secondary uses, by a Data Access Committee or similar internal oversight body with suitable stakeholder representation, should be a required component of the trustworthy governance of any repository of data or specimens.

Country-of-origin effect and consumer brand perception

DEFF Research Database (Denmark)

Iacob, Andreea

This dissertation investigates the impact of country of origin on the brand perception of consumers from developed and emerging countries. Particularly, the aim is to explore the impact of the country of origin on the Western consumers’ brand perception of high involvement products with multiple...... countries of origin and the Central Eastern European consumers’ brand perception of low involvement products from developed countries. It comprises a summary report, consisting of an introduction, a methodology chapter, a conclusions chapter and four research papers....

Archaeal origin of tubulin

Directory of Open Access Journals (Sweden)

Yutin Natalya

2012-03-01

Full Text Available Abstract Tubulins are a family of GTPases that are key components of the cytoskeleton in all eukaryotes and are distantly related to the FtsZ GTPase that is involved in cell division in most bacteria and many archaea. Among prokaryotes, bona fide tubulins have been identified only in bacteria of the genus Prosthecobacter. These bacterial tubulin genes appear to have been horizontally transferred from eukaryotes. Here we describe tubulins encoded in the genomes of thaumarchaeota of the genus Nitrosoarchaeum that we denote artubulins Phylogenetic analysis results are compatible with the origin of eukaryotic tubulins from artubulins. These findings expand the emerging picture of the origin of key components of eukaryotic functional systems from ancestral forms that are scattered among the extant archaea. Reviewers This article was reviewed by Gáspár Jékely and J. Peter Gogarten.