WorldWideScience

Sample records for identify major themes

  1. Unity in Major Themes

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm; Davis, Philip J.

    We describe and explain the desire, common among mathematicians, both for unity and independence in its major themes. In the dialogue that follows, we express our spontaneous and considered judgment and reservations; by contrasting the development of mathematics as a goal-driven process as opposed...

  2. Identifying and Addressing Themes of Job Dissatisfaction for Secondary Principals

    Science.gov (United States)

    De Jong, David; Grundmeyer, Trent; Yankey, Julie

    2017-01-01

    Secondary principals serve in important roles that are complex, high-stress, and include demanding job responsibilities. Key stakeholders such as superintendents, school board members, and legislators must understand the challenges facing secondary principals in order to address the current themes of job dissatisfaction. Using new survey data…

  3. Normative study of theme identifiability: Instructions with and without explanation of the false memory effect.

    Science.gov (United States)

    Beato, Maria Soledad; Cadavid, Sara

    2016-12-01

    False-memory illusions have been widely studied using the Deese/Roediger-McDermott paradigm (DRM). In this paradigm, words semantically related to a single nonpresented critical word are studied. In a later memory test, critical words are often falsely recalled and recognized. The present normative study was conducted to measure the theme identifiability of 60 associative word lists in Spanish that include six words (e.g., stove, coat, blanket, scarf, chill, and bonnet) that are simultaneously associated with three critical words (e.g., HEAT, COLD, and WINTER; Beato & Díez, Psicothema, 26, 457-463, 2011). Different levels of backward associative strength were used in the construction of the DRM lists. In addition, we used two types of instructions to obtain theme identifiability. In the without-explanation condition, traditional instructions were used, requesting participants to write the theme list. In the with-explanation condition, the false-memory effect and how the lists were built were explained, and an example of a DRM list and critical words was shown. Participants then had to discover the critical words. The results showed that all lists produced theme identifiability. Moreover, some lists had a higher theme identifiability rate (e.g., 61 % for the critical words LOVE, BOYFRIEND, COUPLE) than others (e.g., 24 % for CITY, PLACE, VILLAGE). After comparing the theme identifiabilities in the different conditions, the results indicated higher theme identifiability when the false-memory effect was explained than without such an explanation. Overall, these new normative data provide a useful tool for those experiments that, for example, aim to analyze the wide differences observed in false memory with DRM lists and the role of theme identifiability.

  4. Effective use of forensic science in volume crime investigations: identifying recurring themes in the literature.

    Science.gov (United States)

    Ludwig, Anika; Fraser, Jim

    2014-01-01

    New scientific, technological and legal developments, particularly the introduction of national databases for DNA and fingerprints, have led to increased use of forensic science in the investigation of crime. There is an assumption, and in some instances specific assertions, that such developments bring improvements either in broad criminal justice terms or more narrowly in terms of economic or practical efficiencies. The underlying presumption is that the new technological opportunities will be understood and effectively implemented. This research investigates whether such increases in activity have also been accompanied by improvements in the effective use of forensic science. A systematic review of thirty-six reports published (predominantly in England and Wales) since the 1980s, which have considered the use of forensic science in the investigation of volume crimes, was carried out. These reports have identified a number of recurrent themes that influenced how effectively forensic science was used in investigations. The themes identified included forensic knowledge and training of investigators, communication and information exchange between specialists and investigators, timeliness of forensic results, interagency relationships and deployment of crime scene examiner resources. The research findings suggest that these factors continue to hinder the effective use of forensic science despite technological advances and this paper considers their potential causes. © 2013.

  5. Ask an anatomist: Identifying global trends, topics and themes of academic anatomists using twitter.

    Science.gov (United States)

    Marsland, Madeleine J; Lazarus, Michelle D

    2018-05-06

    Social media (SoMe) is increasingly used in higher education (HE) to access knowledge and enable global communication. The SoMe platform Twitter ® is particularly beneficial in these contexts because it is readily accessible, easily searchable (via hashtags) and global. Given these advantages, the twitter platform @AskAnatomist was created to foster a global weekly tweet chat, where students and academics can ask and address anatomy-related questions. The aim of this study was to identify themes arising in the early stages of the @AskAnatomy Twitter community to gain insights into current needs/key areas for academic anatomists, students, and other followers. A qualitative analysis of tweets including the hashtag #AnatQ, (the associated @AskAnatomist hashtag), was undertaken to achieve this aim. Thematic analysis revealed three core themes arising in the formative stages of the @AskAnatomist Twitter site: (1) anatomical education modalities, (2) specific anatomy content, and (3) research motivations. These themes reveal controversies within the field of anatomical sciences, areas for potential education resource improvement and research, as well as the humor of anatomists. Though the original intent of the @AskAnatomist site was to engage the general public in anatomy content and knowledge, tweet analysis suggests that academic anatomists were the primary active "tweeters". Interestingly, this analysis reveals that the @AskAnatomist site progressed into a web-based community of practice (CoP), suggesting an additional benefit of SoMe communities in the field of anatomy. Anat Sci Educ 11: 270-281. © 2017 American Association of Anatomists. © 2017 American Association of Anatomists.

  6. Vocational Interest Themes and Personality Traits in Relation to College Major Satisfaction of Business Students

    Science.gov (United States)

    Logue, Christen T.; Lounsbury, John W.; Gupta, Arpana; Leong, Frederick T. L.

    2007-01-01

    Based on 164 undergraduate business majors, we examined the relationship between satisfaction with major and Holland's vocational interests and with the Big Five and narrow personality traits. Contrary to our hypothesis, enterprising scores were unrelated to major satisfaction. As hypothesized, using ipsative and normative scores, investigative,…

  7. Theme Enrichment Analysis: A Statistical Test for Identifying Significantly Enriched Themes in a List of Stories with an Application to the Star Trek Television Franchise

    OpenAIRE

    Onsjö, Mikael; Sheridan, Paul

    2017-01-01

    In this paper, we describe how the hypergeometric test can be used to determine whether a given theme of interest occurs in a storyset at a frequency more than would be expected by chance. By a storyset we mean simply a list of stories defined according to a common attribute (e.g. author, movement, period). The test works roughly as follows: Given a background storyset (e.g. 19th century adventure novels), and a sub-storyset of interest (e.g. Jules Verne novels), the test determines whether a...

  8. Literature overview highlights lack of paediatric donation protocols but identifies common themes that could guide their development.

    Science.gov (United States)

    Vileito, A; Siebelink, M J; Verhagen, Aae

    2018-05-01

    Paediatric donation is a unique and extremely sensitive process that requires specific knowledge and competencies. Most countries use protocols for organ and tissue donation to ensure optimal care for the donor and family, but these mainly focus on adults. However, the donation process for children differs from adults in many ways. An overview of the literature was performed to identify protocols for the paediatric population. PubMed, Web of Science, EMBASE and the Internet were searched up to March 2016 for papers or other sources in English related to specific organ and tissue donation protocols for children and neonates. This comprised title, abstract and then full-text screening of relevant data. We included 12 papers and two electronic sources that were mainly from North America and Europe. Most discussed donations after cardiac death. The recurring themes included identifying potential donors, approaching parents, palliative care and collaboration with organ procurement organisations. Most papers called for paediatric donation policies to be standardised. Scientific publications in English on paediatric donation protocols are very scarce. No comprehensive paediatric donation protocol was found. We identified several recurring themes in the literature that could be used to develop such protocols. ©2018 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.

  9. Theming Asia

    NARCIS (Netherlands)

    Erb, Maribeth; Ong, Chin Ee

    2017-01-01

    This paper introduces a special issue on Theme Parks in Asia with reflections on how the various theoretical ideas on theming and theme parks that are found in the social science literature can help us to understand the proliferation of theming and theme parks in contemporary Asia. How does theming

  10. Genes2WordCloud: a quick way to identify biological themes from gene lists and free text.

    Science.gov (United States)

    Baroukh, Caroline; Jenkins, Sherry L; Dannenfelser, Ruth; Ma'ayan, Avi

    2011-10-13

    Word-clouds recently emerged on the web as a solution for quickly summarizing text by maximizing the display of most relevant terms about a specific topic in the minimum amount of space. As biologists are faced with the daunting amount of new research data commonly presented in textual formats, word-clouds can be used to summarize and represent biological and/or biomedical content for various applications. Genes2WordCloud is a web application that enables users to quickly identify biological themes from gene lists and research relevant text by constructing and displaying word-clouds. It provides users with several different options and ideas for the sources that can be used to generate a word-cloud. Different options for rendering and coloring the word-clouds give users the flexibility to quickly generate customized word-clouds of their choice. Genes2WordCloud is a word-cloud generator and a word-cloud viewer that is based on WordCram implemented using Java, Processing, AJAX, mySQL, and PHP. Text is fetched from several sources and then processed to extract the most relevant terms with their computed weights based on word frequencies. Genes2WordCloud is freely available for use online; it is open source software and is available for installation on any web-site along with supporting documentation at http://www.maayanlab.net/G2W. Genes2WordCloud provides a useful way to summarize and visualize large amounts of textual biological data or to find biological themes from several different sources. The open source availability of the software enables users to implement customized word-clouds on their own web-sites and desktop applications.

  11. Genes2WordCloud: a quick way to identify biological themes from gene lists and free text

    Directory of Open Access Journals (Sweden)

    Ma'ayan Avi

    2011-10-01

    Full Text Available Abstract Background Word-clouds recently emerged on the web as a solution for quickly summarizing text by maximizing the display of most relevant terms about a specific topic in the minimum amount of space. As biologists are faced with the daunting amount of new research data commonly presented in textual formats, word-clouds can be used to summarize and represent biological and/or biomedical content for various applications. Results Genes2WordCloud is a web application that enables users to quickly identify biological themes from gene lists and research relevant text by constructing and displaying word-clouds. It provides users with several different options and ideas for the sources that can be used to generate a word-cloud. Different options for rendering and coloring the word-clouds give users the flexibility to quickly generate customized word-clouds of their choice. Methods Genes2WordCloud is a word-cloud generator and a word-cloud viewer that is based on WordCram implemented using Java, Processing, AJAX, mySQL, and PHP. Text is fetched from several sources and then processed to extract the most relevant terms with their computed weights based on word frequencies. Genes2WordCloud is freely available for use online; it is open source software and is available for installation on any web-site along with supporting documentation at http://www.maayanlab.net/G2W. Conclusions Genes2WordCloud provides a useful way to summarize and visualize large amounts of textual biological data or to find biological themes from several different sources. The open source availability of the software enables users to implement customized word-clouds on their own web-sites and desktop applications.

  12. A tripartite approach identifies the major sunflower seed albumins.

    Science.gov (United States)

    Jayasena, Achala S; Franke, Bastian; Rosengren, Johan; Mylne, Joshua S

    2016-03-01

    We have used a combination of genomic, transcriptomic, and proteomic approaches to identify the napin-type albumin genes in sunflower and define their contributions to the seed albumin pool. Seed protein content is determined by the expression of what are typically large gene families. A major class of seed storage proteins is the napin-type, water soluble albumins. In this work we provide a comprehensive analysis of the napin-type albumin content of the common sunflower (Helianthus annuus) by analyzing a draft genome, a transcriptome and performing a proteomic analysis of the seed albumin fraction. We show that although sunflower contains at least 26 genes for napin-type albumins, only 15 of these are present at the mRNA level. We found protein evidence for 11 of these but the albumin content of mature seeds is dominated by the encoded products of just three genes. So despite high genetic redundancy for albumins, only a small sub-set of this gene family contributes to total seed albumin content. The three genes identified as producing the majority of sunflower seed albumin are potential future candidates for manipulation through genetics and breeding.

  13. First Workshop on Design and Construction of Deep Repositories - Theme: Excavation through water-conducting major fracture zones

    International Nuclear Information System (INIS)

    Baeckblom, G.; Svemar, C.

    1994-01-01

    Final disposal of high-level nuclear waste has not yet been carried out in any country today. The concepts under development are all based on geological repositories, i.e., disposal at a sufficient depth below the surface to provide stable mechanical, hydrological and chemical conditions during the period the waste needs to be isolated from man. In the cases where crystalline bedrock is considered the proposed repository depths vary between 300-1000 m. The construction, operation and sealing of a deep geological repository must meet various criteria that in many respects are more detailed and more demanding than usual in underground construction projects today. The work shall be done so that occupational safety is ensured. The work also shall conform to whatever restrictions are necessary for ensuring pre-closure operational safety and post-closure long-term safety. March 1993 SKB arranged a two-day international workshop to discuss design and construction of repositories. Close to 40 participants from eight countries shared experiences regarding passage of major water-conducting fracture zones and other matters. This report summarizes the contributions to the workshop

  14. Using the Theme of Mass Extinctions to Teach Science to Non-Science Major College and University Students

    Science.gov (United States)

    Boness, D. A.

    2013-12-01

    The general public is heavily exposed to "news" and commentary---and arts and entertainment---that either inadvertently misrepresents science or even acts to undermine it. Climate change denial and evolution denial is well funded and pervasive. Even university-educated people get little exposure to the aims, methods, debates, and results of scientific inquiry because unless they earn degrees in science they typically only take one or two introductory science courses at the university level. This presentation reports the development of a new, non-science major Seattle University course on mass extinctions throughout earth history. Seattle University is an urban, Jesuit Catholic university. The topic of mass extinctions was chosen for several reasons: (1) To expose the students to a part of current science that has rich historical roots yet by necessity uses methods and reasoning from geology, geophysics, oceanography, physics, chemistry, biology, and astronomy. This multidisciplinary course provides some coverage of sciences that the student would not typically ever see beyond secondary school. (2) To enable the students to learn enough to follow some of the recent and current debates within science (e.g., mass extinctions by asteroid impact versus massive volcanism, ocean anoxia, and ocean acidification), with the students reading some of the actual literature, such as articles in Science, Nature, or Nature Geoscience. (3) To emphasize the importance of "deep time" as evolutionary biological processes interact with massive environmental change over time scales from hundreds of millions of years down to the seconds and hours of an asteroid or comet strike. (4) To show the effects of climate change in the past, present, and future, due to both natural and anthropogenic causes. (5) To help the student critically evaluate the extent to which their future involves a human-caused mass extinction.

  15. Protocol for a thematic synthesis to identify key themes and messages from a palliative care research network.

    LENUS (Irish Health Repository)

    Nicholson, Emma

    2016-10-21

    Research networks that facilitate collaborative research are increasing both regionally and globally and such collaborations contribute greatly to knowledge transfer particularly in health research. The Palliative Care Research Network is an Irish-based network that seeks to create opportunities and engender a collaborative environment to encourage innovative research that is relevant for policy and practice. The current review outlines a methodology to identify cross-cutting messages to identify how dissemination outputs can be optimized to ensure that key messages from this research reaches all knowledge users.

  16. Integrating themes, evidence gaps, and research needs identified by workshop on iron screening and supplementation in iron-replete pregnant women and young children.

    Science.gov (United States)

    Brannon, Patsy M; Stover, Patrick J; Taylor, Christine L

    2017-12-01

    This report addresses the evidence and the uncertainties, knowledge gaps, and research needs identified by participants at the NIH workshop related to iron screening and routine iron supplementation of largely iron-replete pregnant women and young children (6-24 mo) in developed countries. The workshop presentations and panel discussions focused on current understanding and knowledge gaps related to iron homeostasis, measurement of and evidence for iron status, and emerging concerns about supplementing iron-replete members of these vulnerable populations. Four integrating themes emerged across workshop presentations and discussion and centered on 1 ) physiologic or developmental adaptations of iron homeostasis to pregnancy and early infancy, respectively, and their implications, 2 ) improvement of the assessment of iron status across the full continuum from iron deficiency anemia to iron deficiency to iron replete to iron excess, 3 ) the linkage of iron status with health outcomes beyond hematologic outcomes, and 4 ) the balance of benefit and harm of iron supplementation of iron-replete pregnant women and young children. Research that addresses these themes in the context of the full continuum of iron status is needed to inform approaches to the balancing of benefits and harms of screening and routine supplementation. © 2017 American Society for Nutrition.

  17. The Tourism Experience Offered by Religious Theme Parks: Taman Tamadun Islam (TTI) in Malaysia

    OpenAIRE

    Moal - Ulvoas, Gaëlle M

    2016-01-01

    Theme parks are major drivers of tourism development and experience is a central concept in tourism research. This study investigates the experience potential associated with religious theme parks which offer a combination of religious and secular activities. The experiences of visitors to Taman Tamadun Islam (TTI), a Muslim theme park based in Malaysia, are identified through the analysis of visitors’ feedback on Tripadvisor.

  18. Identifying Major Dietary Patterns Among the Elderly in Tehran Health Homes

    Directory of Open Access Journals (Sweden)

    Abdollahi

    2015-10-01

    Full Text Available Background Previous studies on diet have primarily focused on individual nutrients or foods. Recently, the analysis of dietary patterns has emerged as a possible approach for examining food consumption. A literature review revealed no studies of dietary patterns in elderly Iranians. Objectives Our objective was to identify the major dietary intake patterns among the elderly in the health homes located in Zone 5 of Tehran city, Iran. Patients and Methods In this cross-sectional study (descriptive, 368 elderly people (≥ 60 years old were randomly selected. Their usual dietary intake during the past year was assessed using a 168-item semiquantitative food frequency questionnaire. Major food patterns were derived using factor analysis after the classification of food items into 26 groups. Results Four major dietary patterns were identified in the studied population: 1 healthy pattern, characterized by a higher intake of vegetables, tomato and tomato sauce, vegetable oil, olive, and fruits; 2 unhealthy pattern, characterized by a higher intake of red meat, fast food, snacks, sugar, honey and jam, soft drinks, and high-fat dairy products; 3. traditional pattern characterized by intake of whole grains, hydrogenated oil and animal fat, beans, salt, and pickles; and 4 protein-rich pattern, characterized by intake of chicken and poultry, fish, grains, and organ meats. These four major dietary patterns explained 16.3%, 7.5%, 6.7%, and 5.7% of the total variance, respectively. Conclusions Four major dietary patterns were identified in the present studied population that can be used to provide tangible dietary advice for the elderly.

  19. Can subsyndromal manifestations of major depression be identified in children at risk?

    Science.gov (United States)

    Uchida, M; Fitzgerald, M; Lin, K; Carrellas, N; Woodworth, H; Biederman, J

    2017-02-01

    Children of parents with major depression are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop major depressive disorder (MDD). We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/Depression scale in identifying children at the highest risk for pediatric MDD from among the pool of children of parents with MDD or bipolar disorder. The sample was derived from two previously conducted longitudinal case-control family studies of psychiatrically and pediatrically referred youth and their families. For this study, probands were stratified based on the presence or absence of a parental mood disorder. Subsyndromal scores on the CBCL Anxiety/Depression scale significantly separated the children at high risk for pediatric MDD from those at low risk in a variety of functional areas, including social and academic functioning. Additionally, children at genetic risk without elevated CBCL Anxiety/Depression scale scores were largely indistinguishable from controls. These results suggest that the CBCL Anxiety/Depression scale can help identify children at highest risk for pediatric MDD. If implemented clinically, this scale would cost-effectively screen children and identify those most in need of early intervention resources to impede the progression of depression. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Japanese situations to emerging themes

    International Nuclear Information System (INIS)

    Kubota, Ryuji

    2011-01-01

    Japanese regulatory body has audited more than ten cases of licensee's RCA since December 2007. We approve of opinions to emerging themes in 'CSNI Activity Plan', and based on achievements of these audits, Japanese situations to emerging themes are explained. As our conclusion, the more experience to identify HOF licensees have, the more problems may be solved. But as CA is difficult to measure for effectiveness, we propose to develop the outcome indicators such as the frequency of events. (author)

  1. A general method for identifying major hybrid male sterility genes in Drosophila.

    Science.gov (United States)

    Zeng, L W; Singh, R S

    1995-10-01

    The genes responsible for hybrid male sterility in species crosses are usually identified by introgressing chromosome segments, monitored by visible markers, between closely related species by continuous backcrosses. This commonly used method, however, suffers from two problems. First, it relies on the availability of markers to monitor the introgressed regions and so the portion of the genome examined is limited to the marked regions. Secondly, the introgressed regions are usually large and it is impossible to tell if the effects of the introgressed regions are the result of single (or few) major genes or many minor genes (polygenes). Here we introduce a simple and general method for identifying putative major hybrid male sterility genes which is free of these problems. In this method, the actual hybrid male sterility genes (rather than markers), or tightly linked gene complexes with large effects, are selectively introgressed from one species into the background of another species by repeated backcrosses. This is performed by selectively backcrossing heterozygous (for hybrid male sterility gene or genes) females producing fertile and sterile sons in roughly equal proportions to males of either parental species. As no marker gene is required for this procedure, this method can be used with any species pairs that produce unisexual sterility. With the application of this method, a small X chromosome region of Drosophila mauritiana which produces complete hybrid male sterility (aspermic testes) in the background of D. simulans was identified. Recombination analysis reveals that this region contains a second major hybrid male sterility gene linked to the forked locus located at either 62.7 +/- 0.66 map units or at the centromere region of the X chromosome of D. mauritiana.

  2. Education and Development. Major Themes in Education

    Science.gov (United States)

    McMahon, Walter, Ed.

    2011-01-01

    This series addresses the relation of education to knowledge-based growth and broader measures of development beyond growth, central features of the modern world in which education has a central role. This role includes the effects of education on pure economic growth including its effects on the creation, adaptation, and dissemination of new…

  3. Identifying predictors, moderators, and mediators of antidepressant response in major depressive disorder: neuroimaging approaches.

    Science.gov (United States)

    Phillips, Mary L; Chase, Henry W; Sheline, Yvette I; Etkin, Amit; Almeida, Jorge R C; Deckersbach, Thilo; Trivedi, Madhukar H

    2015-02-01

    Despite significant advances in neuroscience and treatment development, no widely accepted biomarkers are available to inform diagnostics or identify preferred treatments for individuals with major depressive disorder. In this critical review, the authors examine the extent to which multimodal neuroimaging techniques can identify biomarkers reflecting key pathophysiologic processes in depression and whether such biomarkers may act as predictors, moderators, and mediators of treatment response that might facilitate development of personalized treatments based on a better understanding of these processes. The authors first highlight the most consistent findings from neuroimaging studies using different techniques in depression, including structural and functional abnormalities in two parallel neural circuits: serotonergically modulated implicit emotion regulation circuitry, centered on the amygdala and different regions in the medial prefrontal cortex; and dopaminergically modulated reward neural circuitry, centered on the ventral striatum and medial prefrontal cortex. They then describe key findings from the relatively small number of studies indicating that specific measures of regional function and, to a lesser extent, structure in these neural circuits predict treatment response in depression. Limitations of existing studies include small sample sizes, use of only one neuroimaging modality, and a focus on identifying predictors rather than moderators and mediators of differential treatment response. By addressing these limitations and, most importantly, capitalizing on the benefits of multimodal neuroimaging, future studies can yield moderators and mediators of treatment response in depression to facilitate significant improvements in shorter- and longer-term clinical and functional outcomes.

  4. Identifying Predictors, Moderators, and Mediators of Antidepressant Response in Major Depressive Disorder: Neuroimaging Approaches

    Science.gov (United States)

    Phillips, Mary L.; Chase, Henry W.; Sheline, Yvette I.; Etkin, Amit; Almeida, Jorge R.C.; Deckersbach, Thilo; Trivedi, Madhukar H.

    2015-01-01

    Objective Despite significant advances in neuroscience and treatment development, no widely accepted biomarkers are available to inform diagnostics or identify preferred treatments for individuals with major depressive disorder. Method In this critical review, the authors examine the extent to which multimodal neuroimaging techniques can identify biomarkers reflecting key pathophysiologic processes in depression and whether such biomarkers may act as predictors, moderators, and mediators of treatment response that might facilitate development of personalized treatments based on a better understanding of these processes. Results The authors first highlight the most consistent findings from neuroimaging studies using different techniques in depression, including structural and functional abnormalities in two parallel neural circuits: serotonergically modulated implicit emotion regulation circuitry, centered on the amygdala and different regions in the medial prefrontal cortex; and dopaminergically modulated reward neural circuitry, centered on the ventral striatum and medial prefrontal cortex. They then describe key findings from the relatively small number of studies indicating that specific measures of regional function and, to a lesser extent, structure in these neural circuits predict treatment response in depression. Conclusions Limitations of existing studies include small sample sizes, use of only one neuroimaging modality, and a focus on identifying predictors rather than moderators and mediators of differential treatment response. By addressing these limitations and, most importantly, capitalizing on the benefits of multimodal neuroimaging, future studies can yield moderators and mediators of treatment response in depression to facilitate significant improvements in shorter- and longer-term clinical and functional outcomes. PMID:25640931

  5. Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

    Science.gov (United States)

    Knight, Jo; Spain, Sarah L; Capon, Francesca; Hayday, Adrian; Nestle, Frank O; Clop, Alex; Barker, Jonathan N; Weale, Michael E; Trembath, Richard C

    2012-12-01

    Psoriasis is a common, chronic, inflammatory skin disorder. A number of genetic loci have been shown to confer risk for psoriasis. Collectively, these offer an integrated model for the inherited basis for susceptibility to psoriasis that combines altered skin barrier function together with the dysregulation of innate immune pathogen sensing and adap-tive immunity. The major histocompatibility complex (MHC) harbours the psoriasis susceptibility region which exhibits the largest effect size, driven in part by variation contained on the HLA-Cw*0602 allele. However, the resolution of the number and genomic location of potential independent risk loci are hampered by extensive linkage disequilibrium across the region. We leveraged the power of large psoriasis case and control data sets and the statistical approach of conditional analysis to identify potential further association signals distributed across the MHC. In addition to the major loci at HLA-C (P = 2.20 × 10(-236)), we observed and replicated four additional independent signals for disease association, three of which are novel. We detected evidence for association at SNPs rs2507971 (P = 6.73 × 10(-14)), rs9260313 (P = 7.93 × 10(-09)), rs66609536 (P = 3.54 × 10(-07)) and rs380924 (P = 6.24 × 10(-06)), located within the class I region of the MHC, with each observation replicated in an independent sample (P ≤ 0.01). The previously identified locus is close to MICA, the other three lie near MICB, HLA-A and HCG9 (a non-coding RNA gene). The identification of disease associations with both MICA and MICB is particularly intriguing, since each encodes an MHC class I-related protein with potent immunological function.

  6. Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease.

    Science.gov (United States)

    Eriksson, D; Bianchi, M; Landegren, N; Nordin, J; Dalin, F; Mathioudaki, A; Eriksson, G N; Hultin-Rosenberg, L; Dahlqvist, J; Zetterqvist, H; Karlsson, Å; Hallgren, Å; Farias, F H G; Murén, E; Ahlgren, K M; Lobell, A; Andersson, G; Tandre, K; Dahlqvist, S R; Söderkvist, P; Rönnblom, L; Hulting, A-L; Wahlberg, J; Ekwall, O; Dahlqvist, P; Meadows, J R S; Bensing, S; Lindblad-Toh, K; Kämpe, O; Pielberg, G R

    2016-12-01

    Autoimmune disease is one of the leading causes of morbidity and mortality worldwide. In Addison's disease, the adrenal glands are targeted by destructive autoimmunity. Despite being the most common cause of primary adrenal failure, little is known about its aetiology. To understand the genetic background of Addison's disease, we utilized the extensively characterized patients of the Swedish Addison Registry. We developed an extended exome capture array comprising a selected set of 1853 genes and their potential regulatory elements, for the purpose of sequencing 479 patients with Addison's disease and 1394 controls. We identified BACH2 (rs62408233-A, OR = 2.01 (1.71-2.37), P = 1.66 × 10 -15 , MAF 0.46/0.29 in cases/controls) as a novel gene associated with Addison's disease development. We also confirmed the previously known associations with the HLA complex. Whilst BACH2 has been previously reported to associate with organ-specific autoimmune diseases co-inherited with Addison's disease, we have identified BACH2 as a major risk locus in Addison's disease, independent of concomitant autoimmune diseases. Our results may enable future research towards preventive disease treatment. © 2016 The Authors. Journal of Internal Medicine published by John Wiley & Sons Ltd on behalf of Association for Publication of The Journal of Internal Medicine.

  7. Enriched pathways for major depressive disorder identified from a genome-wide association study.

    Science.gov (United States)

    Kao, Chung-Feng; Jia, Peilin; Zhao, Zhongming; Kuo, Po-Hsiu

    2012-11-01

    Major depressive disorder (MDD) has caused a substantial burden of disease worldwide with moderate heritability. Despite efforts through conducting numerous association studies and now, genome-wide association (GWA) studies, the success of identifying susceptibility loci for MDD has been limited, which is partially attributed to the complex nature of depression pathogenesis. A pathway-based analytic strategy to investigate the joint effects of various genes within specific biological pathways has emerged as a powerful tool for complex traits. The present study aimed to identify enriched pathways for depression using a GWA dataset for MDD. For each gene, we estimated its gene-wise p value using combined and minimum p value, separately. Canonical pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) and BioCarta were used. We employed four pathway-based analytic approaches (gene set enrichment analysis, hypergeometric test, sum-square statistic, sum-statistic). We adjusted for multiple testing using Benjamini & Hochberg's method to report significant pathways. We found 17 significantly enriched pathways for depression, which presented low-to-intermediate crosstalk. The top four pathways were long-term depression (p⩽1×10-5), calcium signalling (p⩽6×10-5), arrhythmogenic right ventricular cardiomyopathy (p⩽1.6×10-4) and cell adhesion molecules (p⩽2.2×10-4). In conclusion, our comprehensive pathway analyses identified promising pathways for depression that are related to neurotransmitter and neuronal systems, immune system and inflammatory response, which may be involved in the pathophysiological mechanisms underlying depression. We demonstrated that pathway enrichment analysis is promising to facilitate our understanding of complex traits through a deeper interpretation of GWA data. Application of this comprehensive analytic strategy in upcoming GWA data for depression could validate the findings reported in this study.

  8. Themes and challenges in making supply chains socially sustainable

    DEFF Research Database (Denmark)

    Abbasi, Maisam

    2014-01-01

    Purpose Purpose of this paper is to explore and classify pattern of the currently discussed themes and challenges in making supply chains socially sustainable. Design/methodology/approach The methodology was based on a systematic review of the existing literature in order to explore what major...... themes and challenges have been discussed as well as the significant gaps where opportunities for further research can be found. Findings In total five categories of themes were identified, namely goods/service-centric, human-centric, organization-centric, corporate-centric, and management...... holistic view of the pattern of currently discussed themes and challenges may be beneficial in increasing the absorptive capacity of industrial and business practitioners when they design and operationalize innovative strategies in developing sustainable supply chains. Originality/value This paper may...

  9. Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

    Directory of Open Access Journals (Sweden)

    David Lindgren

    Full Text Available Similar to other malignancies, urothelial carcinoma (UC is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of regions harboring recurrent focal genomic amplifications and deletions. Several potential oncogenes were included in the amplified regions, including known oncogenes like E2F3, CCND1, and CCNE1, as well as new candidate genes, such as SETDB1 (1q21, and BCL2L1 (20q11. We next combined genome profiling with global gene expression, gene mutation, and protein expression data and identified two major genomic circuits operating in urothelial carcinoma. The first circuit was characterized by FGFR3 alterations, overexpression of CCND1, and 9q and CDKN2A deletions. The second circuit was defined by E3F3 amplifications and RB1 deletions, as well as gains of 5p, deletions at PTEN and 2q36, 16q, 20q, and elevated CDKN2A levels. TP53/MDM2 alterations were common for advanced tumors within the two circuits. Our data also suggest a possible RAS/RAF circuit. The tumors with worst prognosis showed a gene expression profile that indicated a keratinized phenotype. Taken together, our integrative approach revealed at least two separate networks of genomic alterations linked to the molecular diversity seen in UC, and that these circuits may reflect distinct pathways of tumor development.

  10. Beyond BLASTing: Tertiary and Quaternary Structure Analysis Helps Identify Major Vault Proteins

    Science.gov (United States)

    Daly, Toni K.; Sutherland-Smith, Andrew J.; Penny, David

    2013-01-01

    We examine the advantages of going beyond sequence similarity and use both protein three-dimensional (3D) structure prediction and then quaternary structure (docking) of inferred 3D structures to help evaluate whether comparable sequences can fold into homologous structures with sufficient lateral associations for quaternary structure formation. Our test case is the major vault protein (MVP) that oligomerizes in multiple copies to form barrel-like vault particles and is relatively widespread among eukaryotes. We used the iterative threading assembly refinement server (I-TASSER) to predict whether putative MVP sequences identified by BLASTp and PSI Basic Local Alignment Search Tool are structurally similar to the experimentally determined rodent MVP tertiary structures. Then two identical predicted quaternary structures from I-TASSER are analyzed by RosettaDock to test whether a pair-wise association occurs, and hence whether the oligomeric vault complex is likely to form for a given MVP sequence. Positive controls for the method are the experimentally determined rat (Rattus norvegicus) vault X-ray crystal structure and the purple sea urchin (Strongylocentrotus purpuratus) MVP sequence that forms experimentally observed vaults. These and two kinetoplast MVP structural homologs were predicted with high confidence value, and RosettaDock predicted that these MVP sequences would dock laterally and therefore could form oligomeric vaults. As the negative control, I-TASSER did not predict an MVP-like structure from a randomized rat MVP sequence, even when constrained to the rat MVP crystal structure (PDB:2ZUO), thus further validating the method. The protocol identified six putative homologous MVP sequences in the heterobolosean Naegleria gruberi within the excavate kingdom. Two of these sequences are predicted to be structurally similar to rat MVP, despite being in excess of 300 residues shorter. The method can be used generally to help test predictions of homology via

  11. Byzantine Theme of Chios

    Directory of Open Access Journals (Sweden)

    Anton S. Mokhov

    2016-11-01

    Full Text Available The article is devoted to the study of the Byzantine theme system in the 10th - 11th centuries. The author believes that the reign of Basil II (976-1025 was marked by the mikra themata in Balkans and on Aegean Sea islands. They were in need of effective border defense. Theme of Chios was one of the mikra militaryadministrative districts, which were created in this period. The author detected five leaders of the theme in accordance with the historical sources: protospatharios and strategos Theodoros Beriboes; protospatharios, tagmatophylax and strategos Leon Karikes; protospatharios, tagmatophylax and strategos Bardas Mersiniotes; vestarches and strategos Ioannes Aristenos; vestes and strategos Michael Maurikas. The analysis of the sigillographic data led to the conclusion that the regular tagmata were the base of the military force of theme of Chios. Moreover, the fortress of Volissos was located in the northwest of Chios. The area around the fortress was inhabited by representatives of one ethnic group. They were under the leadership of doux, which was subordinate to the strategos of the theme. The famous officials of the civil administration of Chios included fiscal clerks – dioiketes, horreiarios and judicial clerks – krites of the velon. Theme of Chios had existed for about one hundred years. It was liquidated during the war between Byzantine and Tzachas, Turkish amir of Smyrna.

  12. Tissue plasminogen activator; identifying major barriers related to intravenous injection in ischemic acute cerebral infraction

    Directory of Open Access Journals (Sweden)

    Fariborz Khorvash

    2017-01-01

    Full Text Available Background: According to previous publications, in patients with acute ischemic cerebral infarction, thrombolytic therapy using intravenous tissue plasminogen activator (IV-tPA necessitates precise documentation of symptoms' onset. The aim of this study was to identify major barriers related to the IV-tPA injection in such patients. Materials and Methods: Between the year 2014-2015, patients with definitive diagnosis of acute cerebral infarction (n = 180 who attended the neurology ward located at the Isfahan Alzahra Hospital were studied. To investigate barriers related to door to IV-tPA needle time, personal reasons, and criteria for inclusion or exclusion of patients, three questionnaire forms were designed based on the Food and Drug Administration-approved indications or contraindications. Results: The mean age of males versus females was 60 versus 77.5 years (ranged 23–93 vs. 29–70 years, respectively. Out of total population, only 10.7% transferred to hospital in <4.5 h after the onset of symptoms. Regarding to eligibility for IV-tPA, 68.9% of total population have had criteria for such treatment. Concerning to both items such as transferring to hospital in <4.5 h after the onset of symptoms and eligibility for IV-tPA, only 6.6% of total population met the criteria for such management. There was ignorance or inattention to symptoms in 75% of population studied. There was a mean of 195.92 ± 6.65 min (182.8–209.04 min for door to IV-tPA needle time. Conclusion: Despite the international guidelines for IV-tPA injection within 3–4.5 h of ischemic stroke symptoms' onset, the results of this study revealed that falling time due to ignorance of symptoms, literacy, and living alone might need further attention. As a result, to decrease death and disability, educational programs related to the symptoms' onset by consultant neurologist in Isfahan/Iran seem to be advantageous.

  13. Research in auditing: main themes

    Directory of Open Access Journals (Sweden)

    Marcelo Porte

    Full Text Available ABSTRACT The passage of the Sarbanes-Oxley Act (SOX was a turning point in auditing and in auditors practice for the academic world. Research concerning the characterization of academic production related to auditing is in its third decade. Its analysis is accomplished by means of definition of keywords, abstracts or title, and information on thematic association within the academic production itself in auditing is undisclosed. In order to revise this gap in auditing literature, this study identified the main themes in auditing and their association in post-SOX era by analyzing the content of objectives and hypothesis of 1,650 publications in Web of Science (2002-2014. The findings in this study extended those from the study by Lesage and Wechtler (2012 from 16 auditing thematic typologies to 22. The results demonstrate that the themes audit report & financial statement users, corporate governance, audit market, external audit, socio-economic data of the company, international regulation, and fraud risk & audit risk were the most addressed in the publications about auditing. Corporate governance has a broader association with the other themes in the area. Future researches may use these themes and relate them to the methodologies applied to audit studies.

  14. Theme: Urban Agriculture.

    Science.gov (United States)

    Ellibee, Margaret; And Others

    1990-01-01

    On the theme of secondary agricultural education in urban areas, this issue includes articles on opportunities, future directions, and implications for the profession; creative supervised experiences for horticulture students; floral marketing, multicultural education; and cultural diversity in urban agricultural education. (JOW)

  15. Theme: Parents and Reading.

    Science.gov (United States)

    Jund, Suzanne, Ed.

    1977-01-01

    This journal issue concentrates on the theme "Parents and Reading." It presents articles on sharing books with young children, using public relations in a reading program, guiding preschool learning, assessing language readiness, working with reading problems, and teaching reading readiness in Wisconsin kindergartens. Resources and a review of…

  16. 49 CFR 520.5 - Guidelines for identifying major actions significantly affecting the environment.

    Science.gov (United States)

    2010-10-01

    ... significantly affecting the environment. 520.5 Section 520.5 Transportation Other Regulations Relating to... significantly affecting the environment. (a) General guidelines. The phrase, “major Federal actions significantly affecting the quality of the human environment,” as used in this part, shall be construed with a...

  17. Galleria mellonella model identifies highly virulent strains among all major molecular types of Cryptococcus gattii.

    Directory of Open Access Journals (Sweden)

    Carolina Firacative

    Full Text Available Cryptococcosis is mainly caused by Cryptococcus neoformans. However, the number of cases due to C. gattii is increasing, affecting mainly immunocompetent hosts. C. gattii is divided into four major molecular types, VGI to VGIV, which differ in their host range, epidemiology, antifungal susceptibility and geographic distribution. Besides studies on the Vancouver Island outbreak strains, which showed that the subtype VGIIa is highly virulent compared to the subtype VGIIb, little is known about the virulence of the other major molecular types. To elucidate the virulence potential of the major molecular types of C. gattii, Galleria mellonella larvae were inoculated with ten globally selected strains per molecular type. Survival rates were recorded and known virulence factors were studied. One VGII, one VGIII and one VGIV strain were more virulent (p 0.05, 21 (five VGI, five VGII, four VGIII and seven VGIV were less virulent (p <0.05 while one strain of each molecular type were avirulent. Cell and capsule size of all strains increased markedly during larvae infection (p <0.001. No differences in growth rate at 37°C were observed. Melanin synthesis was directly related with the level of virulence: more virulent strains produced more melanin than less virulent strains (p <0.05. The results indicate that all C. gattii major molecular types exhibit a range of virulence, with some strains having the potential to be more virulent. The study highlights the necessity to further investigate the genetic background of more and less virulent strains in order to recognize critical features, other than the known virulence factors (capsule, melanin and growth at mammalian body temperature, that maybe crucial for the development and progression of cryptococcosis.

  18. FY17 Strategic Themes.

    Energy Technology Data Exchange (ETDEWEB)

    Leland, Robert W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    I am pleased to present this summary of the FY17 Division 1000 Science and Technology Strategic Plan. As this plan represents a continuation of the work we started last year, the four strategic themes (Mission Engagement, Bold Outcomes, Collaborative Environment, and Safety Imperative) remain the same, along with many of the goals. You will see most of the changes in the actions listed for each goal: We completed some actions, modified others, and added a few new ones. As I’ve stated previously, this is not a strategy to be pursued in tension with the Laboratory strategic plan. The Division 1000 strategic plan is intended to chart our course as we strive to contribute our very best in service of the greater Laboratory strategy. I welcome your feedback and look forward to our dialogue about these strategic themes. Please join me as we move forward to implement the plan in the coming months.

  19. FY16 Strategic Themes.

    Energy Technology Data Exchange (ETDEWEB)

    Leland, Robert W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    I am pleased to present this summary of the Division 1000 Science and Technology Strategic Plan. This plan was created with considerable participation from all levels of management in Division 1000, and is intended to chart our course as we strive to contribute our very best in service of the greater Laboratory strategy. The plan is characterized by four strategic themes: Mission Engagement, Bold Outcomes, Collaborative Environment, and the Safety Imperative. Each theme is accompanied by a brief vision statement, several goals, and planned actions to support those goals throughout FY16. I want to be clear that this is not a strategy to be pursued in tension with the Laboratory strategic plan. Rather, it is intended to describe “how” we intend to show up for the “what” described in Sandia’s Strategic Plan. I welcome your feedback and look forward to our dialogue about these strategic themes. Please join me as we move forward to implement the plan in the coming year.

  20. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

    Science.gov (United States)

    Wray, Naomi R; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M; Abdellaoui, Abdel; Adams, Mark J; Agerbo, Esben; Air, Tracy M; Andlauer, Till M F; Bacanu, Silviu-Alin; Bækvad-Hansen, Marie; Beekman, Aartjan F T; Bigdeli, Tim B; Binder, Elisabeth B; Blackwood, Douglas R H; Bryois, Julien; Buttenschøn, Henriette N; Bybjerg-Grauholm, Jonas; Cai, Na; Castelao, Enrique; Christensen, Jane Hvarregaard; Clarke, Toni-Kim; Coleman, Jonathan I R; Colodro-Conde, Lucía; Couvy-Duchesne, Baptiste; Craddock, Nick; Crawford, Gregory E; Crowley, Cheynna A; Dashti, Hassan S; Davies, Gail; Deary, Ian J; Degenhardt, Franziska; Derks, Eske M; Direk, Nese; Dolan, Conor V; Dunn, Erin C; Eley, Thalia C; Eriksson, Nicholas; Escott-Price, Valentina; Kiadeh, Farnush Hassan Farhadi; Finucane, Hilary K; Forstner, Andreas J; Frank, Josef; Gaspar, Héléna A; Gill, Michael; Giusti-Rodríguez, Paola; Goes, Fernando S; Gordon, Scott D; Grove, Jakob; Hall, Lynsey S; Hannon, Eilis; Hansen, Christine Søholm; Hansen, Thomas F; Herms, Stefan; Hickie, Ian B; Hoffmann, Per; Homuth, Georg; Horn, Carsten; Hottenga, Jouke-Jan; Hougaard, David M; Hu, Ming; Hyde, Craig L; Ising, Marcus; Jansen, Rick; Jin, Fulai; Jorgenson, Eric; Knowles, James A; Kohane, Isaac S; Kraft, Julia; Kretzschmar, Warren W; Krogh, Jesper; Kutalik, Zoltán; Lane, Jacqueline M; Li, Yihan; Li, Yun; Lind, Penelope A; Liu, Xiaoxiao; Lu, Leina; MacIntyre, Donald J; MacKinnon, Dean F; Maier, Robert M; Maier, Wolfgang; Marchini, Jonathan; Mbarek, Hamdi; McGrath, Patrick; McGuffin, Peter; Medland, Sarah E; Mehta, Divya; Middeldorp, Christel M; Mihailov, Evelin; Milaneschi, Yuri; Milani, Lili; Mill, Jonathan; Mondimore, Francis M; Montgomery, Grant W; Mostafavi, Sara; Mullins, Niamh; Nauck, Matthias; Ng, Bernard; Nivard, Michel G; Nyholt, Dale R; O'Reilly, Paul F; Oskarsson, Hogni; Owen, Michael J; Painter, Jodie N; Pedersen, Carsten Bøcker; Pedersen, Marianne Giørtz; Peterson, Roseann E; Pettersson, Erik; Peyrot, Wouter J; Pistis, Giorgio; Posthuma, Danielle; Purcell, Shaun M; Quiroz, Jorge A; Qvist, Per; Rice, John P; Riley, Brien P; Rivera, Margarita; Saeed Mirza, Saira; Saxena, Richa; Schoevers, Robert; Schulte, Eva C; Shen, Ling; Shi, Jianxin; Shyn, Stanley I; Sigurdsson, Engilbert; Sinnamon, Grant B C; Smit, Johannes H; Smith, Daniel J; Stefansson, Hreinn; Steinberg, Stacy; Stockmeier, Craig A; Streit, Fabian; Strohmaier, Jana; Tansey, Katherine E; Teismann, Henning; Teumer, Alexander; Thompson, Wesley; Thomson, Pippa A; Thorgeirsson, Thorgeir E; Tian, Chao; Traylor, Matthew; Treutlein, Jens; Trubetskoy, Vassily; Uitterlinden, André G; Umbricht, Daniel; Van der Auwera, Sandra; van Hemert, Albert M; Viktorin, Alexander; Visscher, Peter M; Wang, Yunpeng; Webb, Bradley T; Weinsheimer, Shantel Marie; Wellmann, Jürgen; Willemsen, Gonneke; Witt, Stephanie H; Wu, Yang; Xi, Hualin S; Yang, Jian; Zhang, Futao; Arolt, Volker; Baune, Bernhard T; Berger, Klaus; Boomsma, Dorret I; Cichon, Sven; Dannlowski, Udo; de Geus, E C J; DePaulo, J Raymond; Domenici, Enrico; Domschke, Katharina; Esko, Tõnu; Grabe, Hans J; Hamilton, Steven P; Hayward, Caroline; Heath, Andrew C; Hinds, David A; Kendler, Kenneth S; Kloiber, Stefan; Lewis, Glyn; Li, Qingqin S; Lucae, Susanne; Madden, Pamela F A; Magnusson, Patrik K; Martin, Nicholas G; McIntosh, Andrew M; Metspalu, Andres; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Nordentoft, Merete; Nöthen, Markus M; O'Donovan, Michael C; Paciga, Sara A; Pedersen, Nancy L; Penninx, Brenda W J H; Perlis, Roy H; Porteous, David J; Potash, James B; Preisig, Martin; Rietschel, Marcella; Schaefer, Catherine; Schulze, Thomas G; Smoller, Jordan W; Stefansson, Kari; Tiemeier, Henning; Uher, Rudolf; Völzke, Henry; Weissman, Myrna M; Werge, Thomas; Winslow, Ashley R; Lewis, Cathryn M; Levinson, Douglas F; Breen, Gerome; Børglum, Anders D; Sullivan, Patrick F

    2018-05-01

    Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide association meta-analysis based in 135,458 cases and 344,901 controls and identified 44 independent and significant loci. The genetic findings were associated with clinical features of major depression and implicated brain regions exhibiting anatomical differences in cases. Targets of antidepressant medications and genes involved in gene splicing were enriched for smaller association signal. We found important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia: lower educational attainment and higher body mass were putatively causal, whereas major depression and schizophrenia reflected a partly shared biological etiology. All humans carry lesser or greater numbers of genetic risk factors for major depression. These findings help refine the basis of major depression and imply that a continuous measure of risk underlies the clinical phenotype.

  1. Effects of Major Sudden Stratospheric Warmings Identified in Midlatitude Mesospheric Rayleigh-Scatter Lidar Temperatures

    Science.gov (United States)

    Sox, L.; Wickwar, V. B.; Fish, C. S.; Herron, J. P.

    2014-12-01

    Mesospheric temperature anomalies associated with Sudden Stratospheric Warmings (SSWs) have been observed extensively in the polar regions. However, observations of these anomalies at midlatitudes are sparse. The very dense 11-year data set, collected between 1993-2004, with the Rayleigh-scatter lidar at the Atmospheric Lidar Observatory (ALO; 41.7°N, 111.8°W) at the Center for Atmospheric and Space Sciences (CASS) on the campus of Utah State University (USU), has been carefully examined for such anomalies. The temperatures derived from these data extend over the mesosphere, from 45 to 90 km. During this period extensive data were acquired during seven major SSW events. In this work we aim to determine the characteristics of the midlatitude mesospheric temperatures during these seven major SSWs. To do this, comparisons were made between the temperature profiles on individual nights before, during, and after the SSW events and the corresponding derived climatological temperature profiles (31-day by 11-year average) for those nights. A consistent disturbance pattern was observed in the mesospheric temperatures during these SSWs. A distinct shift from the nominal winter temperature pattern to a pattern more characteristic of summer temperatures was seen in the midlatitude mesosphere close to when the zonal winds in the polar stratosphere (at 10 hPa, 60° N) reversed from eastward to westward. This shift lasted for several days. This change in pattern included coolings in the upper mesosphere, comparable to those seen in the polar regions, and warmings in the lower mesosphere.

  2. Whole genome population genetics analysis of Sudanese goats identifies regions harboring genes associated with major traits.

    Science.gov (United States)

    Rahmatalla, Siham A; Arends, Danny; Reissmann, Monika; Said Ahmed, Ammar; Wimmers, Klaus; Reyer, Henry; Brockmann, Gudrun A

    2017-10-23

    Sudan is endowed with a variety of indigenous goat breeds which are used for meat and milk production and which are well adapted to the local environment. The aim of the present study was to determine the genetic diversity and relationship within and between the four main Sudanese breeds of Nubian, Desert, Taggar and Nilotic goats. Using the 50 K SNP chip, 24 animals of each breed were genotyped. More than 96% of high quality SNPs were polymorphic with an average minor allele frequency of 0.3. In all breeds, no significant difference between observed (0.4) and expected (0.4) heterozygosity was found and the inbreeding coefficients (F IS ) did not differ from zero. F st coefficients for the genetic distance between breeds also did not significantly deviate from zero. In addition, the analysis of molecular variance revealed that 93% of the total variance in the examined population can be explained by differences among individuals, while only 7% result from differences between the breeds. These findings provide evidence for high genetic diversity and little inbreeding within breeds on one hand, and low diversity between breeds on the other hand. Further examinations using Nei's genetic distance and STRUCTURE analysis clustered Taggar goats distinct from the other breeds. In a principal component (PC) analysis, PC1 could separate Taggar, Nilotic and a mix of Nubian and Desert goats into three groups. The SNPs that contributed strongly to PC1 showed high F st values in Taggar goat versus the other goat breeds. PCA allowed us to identify target genomic regions which contain genes known to influence growth, development, bone formation and the immune system. The information on the genetic variability and diversity in this study confirmed that Taggar goat is genetically different from the other goat breeds in Sudan. The SNPs identified by the first principal components show high F st values in Taggar goat and allowed to identify candidate genes which can be used in the

  3. Shakespearean tragedies dynamics: identifying a generic structure in Shakespeare's four major tragedies

    Science.gov (United States)

    Domínguez-Rué, Emma; Mrotzek, Maximilian

    2012-10-01

    Many interpretations of Shakespearean tragedy have been conducted, mostly following the principles of interpretation in literary study. In our paper, four tragedies by William Shakespeare - Hamlet, King Lear, Othello, and Macbeth - were analysed systemically to find out whether they inhabit a common structure. Using the plot structure as the basis for our analysis, we identified the most important system elements, their connections, and interactive behaviour using causal loop diagrams (CLDs). Our results revealed that all four tragedies basically conform to Senge's archetypal structure 'shifting the burden', adding the action of the heroine or villain and the characters' boundaries of perception. The results suggest that, even though characters and settings vary highly, these tragedies have similar structures and archetypal solutions exist to overcome the problem. Furthermore, we propose that CLDs and systems archetypes are a reasonable hermeneutic tool to analyse not only Shakespearean tragedies but also other literary works.

  4. Google Earth Grand Tour Themes

    Science.gov (United States)

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  5. Instant premium Drupal themes

    CERN Document Server

    Sharma, Pankaj

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. A step-by-step guide filled with recipes that will show you how to create your very own Drupal themes using HTML.This book is great for developers who are new to Drupal. It is assumed that you have some experience in HTML, PHP, and CSS. You'll need a PHP (LAMP/WAMP) environment to install Drupal. It is also assumed that you know how to install Drupal. Some familiarity with CMS will be useful but is not essential.

  6. Drupal 7 Theming Cookbook

    CERN Document Server

    Kumar, Karthik

    2012-01-01

    Part of Packt's Cookbook series, this book offers solutions to common theme design problems in the form of recipes. Each recipe contains step-by-step instructions and screenshots. The book is designed so that you can read it chapter by chapter, or you can refer to each recipe in no particular order. This book is for Drupal developers and administrators who want to refresh the look and feel of their site. We assume that readers are familiar with basic PHP, CSS, and XHTML as well as the general use of Drupal.

  7. Identifying Major Transitions in the Evolution of Lithic Cutting Edge Production Rates.

    Directory of Open Access Journals (Sweden)

    Antoine Muller

    Full Text Available The notion that the evolution of core reduction strategies involved increasing efficiency in cutting edge production is prevalent in narratives of hominin technological evolution. Yet a number of studies comparing two different knapping technologies have found no significant differences in edge production. Using digital analysis methods we present an investigation of raw material efficiency in eight core technologies broadly representative of the long-term evolution of lithic technology. These are bipolar, multiplatform, discoidal, biface, Levallois, prismatic blade, punch blade and pressure blade production. Raw material efficiency is assessed by the ratio of cutting edge length to original core mass. We also examine which flake attributes contribute to maximising raw material efficiency, as well as compare the difference between expert and intermediate knappers in terms of cutting edge produced per gram of core. We identify a gradual increase in raw material efficiency over the broad sweep of lithic technological evolution. The results indicate that the most significant transition in efficiency likely took place with the introduction of small foliate biface, Levallois and prismatic blade knapping, all introduced in the Middle Stone Age / Middle Palaeolithic among early Homo sapiens and Neanderthals. This suggests that no difference in raw material efficiency existed between these species. With prismatic blade technology securely dated to the Middle Palaeolithic, by including the more recent punch and pressure blade technology our results dispel the notion that the transition to the Upper Palaeolithic was accompanied by an increase in efficiency. However, further increases in cutting edge efficiency are evident, with pressure blades possessing the highest efficiency in this study, indicating that late/epi-Palaeolithic and Neolithic blade technologies further increased efficiency.

  8. The Theme of Risk Management

    Directory of Open Access Journals (Sweden)

    Chua, D. K. H.

    2014-07-01

    Full Text Available The papers in this issue of the Journal come from different industry sectors, yet there can be a common theme that ties them together. Two of the papers address explicitly the issue of risk management, while the other three may be related to it in different degrees. One of the critical factors for project success is risk identification, as determined by Chua et al. (1999. The importance of risk management cannot be overemphasized. Failure to identify crucial risk elements in a project can lead to significant project failures in terms of cost and schedule.

  9. Identifying and characterizing major emission point sources as a basis for geospatial distribution of mercury emissions inventories

    NARCIS (Netherlands)

    Steenhuisen, Frits; Wilson, Simon J.

    Mercury is a global pollutant that poses threats to ecosystem and human health. Due to its global transport, mercury contamination is found in regions of the Earth that are remote from major emissions areas, including the Polar regions. Global anthropogenic emission inventories identify important

  10. In or Out When Out & About?: Identifying the Professional Support Needs of LGBT Preservice Social Work & Education Majors

    Science.gov (United States)

    Palladino, John M.; Giesler, Mark A.

    2014-01-01

    The purpose of this phenomenological qualitative study was to explore how preservice social work and teacher education majors navigate field practicums (e.g., student teaching) as self-identified gay, lesbian, bisexual, or transgender (LGBT) individuals. In-depth interviews with 26 preservice candidates, representative of two public, comprehensive…

  11. Suicide note themes and suicide prevention.

    Science.gov (United States)

    Foster, Tom

    2003-01-01

    The aim was to determine if suicide note themes might inform suicide prevention strategies. The themes of 42 suicide notes from the Northern Ireland Suicide Study (major psychological autopsy study) were examined. The commonest themes were "apology/shame" (74%), "love for those left behind" (60%), "life too much to bear" (48%), "instructions regarding practical affairs post-mortem" (36%), "hopelessness/nothing to live for" (21%) and "advice for those left behind" (21%). Notes of suicides with major unipolar depression were more likely than notes of suicides without major unipolar depression to contain the themes "instructions regarding practical affairs post-mortem" (67% versus 19%, p = 0.005) and "hopelessness/nothing to live for" (40% versus 11%, p = 0.049). Notes of suicides with a previous history of deliberate self-harm were less likely than notes of suicides without a history of deliberate self-harm to contain the theme "apology/shame" (58% versus 87%, p = 0.04). Notes of elderly suicides were more likely than non-elderly notes to contain the theme "burden to others" (40% versus 3%, p = 0.03). The fact that three quarters of suicide notes contained the theme "apology/shame" suggests that the deceased may have welcomed alternative solutions for their predicaments. Scrutiny of suicide note themes in the light of previous research findings suggests that cognitive therapy techniques, especially problem solving, may have an important role to play in suicide prevention and that potential major unipolar depressive (possibly less impulsive) suicides, in particular, may provide fertile ground for therapeutic intervention (physical and psychological). Ideally all primary care doctors and mental health professionals working with (potentially) suicidal people should be familiar with basic cognitive therapy techniques, especially problem solving skills training.

  12. Particle physics: Themes and challenges

    International Nuclear Information System (INIS)

    Quigg, C.

    1995-11-01

    I will devote this lecture to seven themes that express the essence of our understanding and our possibilities. These themes are: elementarity, symmetry, consistency, unity, identity, opportunity, and relevance

  13. Particle physics: Themes and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Quigg, C.

    1995-11-01

    I will devote this lecture to seven themes that express the essence of our understanding and our possibilities. These themes are: elementarity, symmetry, consistency, unity, identity, opportunity, and relevance.

  14. RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord.

    Directory of Open Access Journals (Sweden)

    David G Brohawn

    Full Text Available ALS is a rapidly progressive, devastating neurodegenerative illness of adults that produces disabling weakness and spasticity arising from death of lower and upper motor neurons. No meaningful therapies exist to slow ALS progression, and molecular insights into pathogenesis and progression are sorely needed. In that context, we used high-depth, next generation RNA sequencing (RNAseq, Illumina to define gene network abnormalities in RNA samples depleted of rRNA and isolated from cervical spinal cord sections of 7 ALS and 8 CTL samples. We aligned >50 million 2X150 bp paired-end sequences/sample to the hg19 human genome and applied three different algorithms (Cuffdiff2, DEseq2, EdgeR for identification of differentially expressed genes (DEG's. Ingenuity Pathways Analysis (IPA and Weighted Gene Co-expression Network Analysis (WGCNA identified inflammatory processes as significantly elevated in our ALS samples, with tumor necrosis factor (TNF found to be a major pathway regulator (IPA and TNFα-induced protein 2 (TNFAIP2 as a major network "hub" gene (WGCNA. Using the oPOSSUM algorithm, we analyzed transcription factors (TF controlling expression of the nine DEG/hub genes in the ALS samples and identified TF's involved in inflammation (NFkB, REL, NFkB1 and macrophage function (NR1H2::RXRA heterodimer. Transient expression in human iPSC-derived motor neurons of TNFAIP2 (also a DEG identified by all three algorithms reduced cell viability and induced caspase 3/7 activation. Using high-density RNAseq, multiple algorithms for DEG identification, and an unsupervised gene co-expression network approach, we identified significant elevation of inflammatory processes in ALS spinal cord with TNF as a major regulatory molecule. Overexpression of the DEG TNFAIP2 in human motor neurons, the population most vulnerable to die in ALS, increased cell death and caspase 3/7 activation. We propose that therapies targeted to reduce inflammatory TNFα signaling may be

  15. Identifying and characterizing major emission point sources as a basis for geospatial distribution of mercury emissions inventories

    Science.gov (United States)

    Steenhuisen, Frits; Wilson, Simon J.

    2015-07-01

    Mercury is a global pollutant that poses threats to ecosystem and human health. Due to its global transport, mercury contamination is found in regions of the Earth that are remote from major emissions areas, including the Polar regions. Global anthropogenic emission inventories identify important sectors and industries responsible for emissions at a national level; however, to be useful for air transport modelling, more precise information on the locations of emission is required. This paper describes the methodology applied, and the results of work that was conducted to assign anthropogenic mercury emissions to point sources as part of geospatial mapping of the 2010 global anthropogenic mercury emissions inventory prepared by AMAP/UNEP. Major point-source emission sectors addressed in this work account for about 850 tonnes of the emissions included in the 2010 inventory. This work allocated more than 90% of these emissions to some 4600 identified point source locations, including significantly more point source locations in Africa, Asia, Australia and South America than had been identified during previous work to geospatially-distribute the 2005 global inventory. The results demonstrate the utility and the limitations of using existing, mainly public domain resources to accomplish this work. Assumptions necessary to make use of selected online resources are discussed, as are artefacts that can arise when these assumptions are applied to assign (national-sector) emissions estimates to point sources in various countries and regions. Notwithstanding the limitations of the available information, the value of this procedure over alternative methods commonly used to geo-spatially distribute emissions, such as use of 'proxy' datasets to represent emissions patterns, is illustrated. Improvements in information that would facilitate greater use of these methods in future work to assign emissions to point-sources are discussed. These include improvements to both national

  16. Methodological themes and variations

    International Nuclear Information System (INIS)

    Tetlock, P.E.

    1989-01-01

    This paper reports on the tangible progress that has been made in clarifying the underlying processes that affect both the likelihood of war in general and of nuclear war in particular. It also illustrates how difficult it is to make progress in this area. Nonetheless, what has been achieved should not be minimized. We have learned a good deal on both the theoretical and the methodological fronts and, perhaps, most important, we have learned a good deal about the limits of our knowledge. Knowledge of our ignorance---especially in a policy domain where confident, even glib, causal assertions are so common---can be a major contribution in itself. The most important service the behavioral and social sciences can currently provide to the policy making community may well be to make thoughtful skepticism respectable: to sensitize those who make key decisions to the uncertainty surrounding our understanding of international conflict and to the numerous qualifications that now need to be attached to simple causal theories concerning the origins of war

  17. Activities Using a Restaurant Theme.

    Science.gov (United States)

    Modlin, Ruth

    Designed for use with elementary students, 44 activities using a restaurant theme integrate creative thinking and decision-making skills with language arts, mathematics, and art. The activities, which can be used independently by the students, deal with types of restaurants, names and themes, floor plans, interior and exterior design, house…

  18. Genome-wide association study identifies major loci for carcass weight on BTA14 in Hanwoo (Korean cattle.

    Directory of Open Access Journals (Sweden)

    Seung Hwan Lee

    Full Text Available This genome-wide association study (GWAS was conducted to identify major loci that are significantly associated with carcass weight, and their effects, in order to provide increased understanding of the genetic architecture of carcass weight in Hanwoo. This genome-wide association study identified one major chromosome region ranging from 23 Mb to 25 Mb on chromosome 14 as being associated with carcass weight in Hanwoo. Significant Bonferroni-corrected genome-wide associations (P<1.52×10(-6 were detected for 6 Single Nucleotide Polymorphic (SNP loci for carcass weight on chromosome 14. The most significant SNP was BTB-01280026 (P = 4.02×10(-11, located in the 25 Mb region on Bos taurus autosome 14 (BTA14. The other 5 significant SNPs were Hapmap27934-BTC-065223 (P = 4.04×10(-11 in 25.2 Mb, BTB-01143580 (P = 6.35×10(-11 in 24.3 Mb, Hapmap30932-BTC-011225 (P = 5.92×10(-10 in 24.8 Mb, Hapmap27112-BTC-063342 (P = 5.18×10(-9 in 25.4 Mb, and Hapmap24414-BTC-073009 (P = 7.38×10(-8 in 25.4 Mb, all on BTA 14. One SNP (BTB-01143580; P = 6.35×10(-11 lies independently from the other 5 SNPs. The 5 SNPs that lie together showed a large Linkage disequilibrium (LD block (block size of 553 kb with LD coefficients ranging from 0.53 to 0.89 within the block. The most significant SNPs accounted for 6.73% to 10.55% of additive genetic variance, which is quite a large proportion of the total additive genetic variance. The most significant SNP (BTB-01280026; P = 4.02×10(-11 had 16.96 kg of allele substitution effect, and the second most significant SNP (Hapmap27934-BTC-065223; P = 4.04×10(-11 had 18.06 kg of effect on carcass weight, which correspond to 44% and 47%, respectively, of the phenotypic standard deviation for carcass weight in Hanwoo cattle. Our results demonstrated that carcass weight was affected by a major Quantitative Trait Locus (QTL with a large effect and by many SNPs with small effects that are normally

  19. Optimal anthropometric measures and thresholds to identify undiagnosed type 2 diabetes in three major Asian ethnic groups.

    Science.gov (United States)

    Alperet, Derrick Johnston; Lim, Wei-Yen; Mok-Kwee Heng, Derrick; Ma, Stefan; van Dam, Rob M

    2016-10-01

    To identify optimal anthropometric measures and cutoffs to identify undiagnosed diabetes mellitus (UDM) in three major Asian ethnic groups (Chinese, Malays, and Asian-Indians). Cross-sectional data were analyzed from 14,815 ethnic Chinese, Malay, and Asian-Indian participants of the Singapore National Health Surveys, which included anthropometric measures and an oral glucose tolerance test. Receiver operating characteristic curve analyses were used with calculation of the area under the curve (AUC) to evaluate the performance of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHTR) for the identification of UDM. BMI performed significantly worse (AUCMEN  = 0.70; AUCWOMEN  = 0.75) than abdominal measures, whereas WHTR (AUCMEN  = 0.76; AUCWOMEN  = 0.79) was among the best performing measures in both sexes and all ethnic groups. Anthropometric measures performed better in Chinese than in Asian-Indian participants for the identification of UDM. A WHTR cutoff of 0.52 appeared optimal with a sensitivity of 76% in men and 73% in women and a specificity of 63% in men and 70% in women. Although ethnic differences were observed in the performance of anthropometric measures for the identification of UDM, abdominal adiposity measures generally performed better than BMI, and WHTR performed best in all Asian ethnic groups. © 2016 The Obesity Society.

  20. Particle physics. Themes and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Quigg, C. [Fermi National Accelerator Laboratory, Batavia, IL (United States)

    1996-12-31

    It is an introductory talk to the Second Rencontres du Vietnam. This lecture is devoted to seven themes that express the essence of our understanding - and our possibilities on particle physics. (K.A.) 19 refs.

  1. [Theme: Achieving Quality Laboratory Projects.[.

    Science.gov (United States)

    Shinn, Glen C.; And Others

    1983-01-01

    The theme articles present strategies for achieving quality laboratory projects in vocational agriculture. They describe fundamentals of the construction of quality projects and stress the importance of quality instruction. (JOW)

  2. Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver.

    Science.gov (United States)

    Papageorgiou, Ioannis; Freytsis, Marina; Court, Michael H

    2016-10-01

    Acetaminophen is the leading cause of acute liver failure (ALF) in many countries including the United States. Hepatic glucuronidation by UDP-glucuronosyltransferase (UGT) 1A subfamily enzymes is the major route of acetaminophen elimination. Reduced glucuronidation may predispose some individuals to acetaminophen-induced ALF, but mechanisms underlying reduced glucuronidation are poorly understood. We hypothesized that specific microRNAs (miRNAs) may reduce UGT1A activity by direct effects on the UGT1A 3'-UTR shared by all UGT1A enzyme transcripts, or by indirect effects on transcription factors regulating UGT1A expression. We performed an unbiased miRNA whole transcriptome association analysis using a bank of human livers with known acetaminophen glucuronidation activities. Of 754 miRNAs evaluated, 9 miRNAs were identified that were significantly overexpressed (p2-fold) in livers with low acetaminophen glucuronidation activities compared with those with high activities. miR-375 showed the highest difference (>10-fold), and was chosen for further mechanistic validation. We demonstrated using in silico analysis and luciferase reporter assays that miR-375 has a unique functional binding site in the 3'-UTR of the aryl hydrocarbon receptor (AhR) gene. Furthermore overexpression of miR-375 in LS180 cells demonstrated significant repression of endogenous AhR protein (by 40%) and mRNA (by 10%), as well as enzyme activity and/or mRNA of AhR regulated enzymes including UGT1A1, UGT1A6, and CYP1A2, without affecting UGT2B7, which is not regulated by AhR. Thus miR-375 is identified as a novel repressor of UGT1A-mediated hepatic acetaminophen glucuronidation through reduced AhR expression, which could predispose some individuals to increased risk for acetaminophen-induced ALF. Published by Elsevier Inc.

  3. Architectural heritage or theme park

    Directory of Open Access Journals (Sweden)

    Ignasi Solà-Morales

    1998-04-01

    Full Text Available The growing parallelism between the perception and the consumer use of theme parks and architectural heritage gives rise to a reflection about the fact that the architectural object has been turned into a museum piece, stripped  of its original value and its initial cultural substance to become images exposed to multiple gazes, thus producing what the author calis the "Theme Park effect", with consequences on protected architecture.

  4. Content Themes of Alcohol Advertising in U.S. Television-Latent Class Analysis.

    Science.gov (United States)

    Morgenstern, Matthis; Schoeppe, Franziska; Campbell, Julie; Braam, Marloes W G; Stoolmiller, Michael; Sargent, James D

    2015-09-01

    There is little alcohol research that reports on the thematic contents of contemporary alcohol advertisements in U.S. television. Studies of alcohol ads from 2 decades ago did not identify "Partying" as a social theme. Aim of this study was to describe and classify alcohol advertisements aired in national television in terms of contents, airing times, and channel placements and to identify different marketing strategies of alcohol brands. Content analysis of all ads from the top 20 U.S. beer and spirit brands aired between July 2009 and June 2011. These were 581 unique alcohol ads accounting for 272,828 (78%) national television airings. Ads were coded according to predefined definitions of 13 content areas. A latent class analysis (LCA) was conducted to define content cluster themes and determine alcoholic brands that were more likely to exploit these themes. About half of the advertisements (46%) were aired between 3 am and 8 pm, and the majority were placed either in Entertainment (40%) and Sports (38%) channels. Beer ads comprised 64% of the sample, with significant variation in airing times and channels between types of products and brands. LCA revealed 5 content classes that exploited the "Partying," "Quality," "Sports," "Manly," and "Relax" themes. The partying class, indicative of ad messages surrounding partying, love, and sex, was the dominant theme comprising 42% of all advertisements. Ads for alcopops, flavored spirits, and liqueur were more likely to belong to the party class, but there were also some beer brands (Corona, Heineken) where more than 67% of ads exploited this theme. This is the first analysis to identify a partying theme to contemporary alcohol advertising. Future analyses can now determine whether exposure to that or other themes predicts alcohol misuse among youth audiences. Copyright © 2015 by the Research Society on Alcoholism.

  5. Content Themes of Alcohol Advertising in US Television — Latent Class Analysis

    Science.gov (United States)

    Morgenstern, Matthis; Schoeppe, Franziska; Campbell, Julie; Braam, Marloes W.G.; Stoolmiller, Michael; Sargent, James D.

    2015-01-01

    Background There is little alcohol research that reports on the thematic contents of contemporary alcohol advertisements in US television. Studies of alcohol ads from two decades ago did not identify “partying” as a social theme. Aim of the present study was to describe and classify alcohol advertisements aired in national television in terms of contents, airing times, and channel placements and to identify different marketing strategies of alcohol brands. Methods Content analysis of all ads from the top 20 US beer and spirit brands aired between July 2009 and June 2011. These were 581 unique alcohol ads accounting for 272,828 (78%) national television airings. Ads were coded according to predefined definitions of 13 content areas. A latent class analysis (LCA) was conducted to define content cluster themes and determine alcoholic brands that were more likely to exploit these themes. Results About half of the advertisements (46%) were aired between 3am and 8pm, and the majority were placed either in Entertainment (40%) and Sports (38%) channels. Beer ads comprised 64% of the sample, with significant variation in airing times and channels between types of products and brands. LCA revealed five content classes that exploited the “Partying”, “Quality”, “Sports”, “Manly”, and “Relax” themes. The partying class, indicative of ad messages surrounding partying, love and sex, was the dominant theme, comprising 42% of all advertisements. Ads for alcopops, flavored spirits, and liqueur were more likely to belong to the party class, but there were also some beer brands (Corona, Heineken) where more than 67% of ads exploited this theme. Conclusions This is the first analysis to identify a partying theme to contemporary alcohol advertising. Future analyses can now determine whether exposure to that or other themes predicts alcohol misuse among youth audiences. PMID:26207317

  6. Functional genomic analysis identifies indoxyl sulfate as a major, poorly dialyzable uremic toxin in end-stage renal disease.

    Directory of Open Access Journals (Sweden)

    Sachin Jhawar

    Full Text Available Chronic renal failure is characterized by progressive renal scarring and accelerated arteriosclerotic cardiovascular disease despite what is considered to be adequate hemodialysis or peritoneal dialysis. In rodents with reduced renal mass, renal scarring has been attributed to poorly filtered, small protein-bound molecules. The best studied of these is indoxyl sulfate (IS.We have attempted to establish whether there are uremic toxins that are not effectively removed by hemodialysis. We examined plasma from patients undergoing hemodialysis, employing global gene expression in normal human renal cortical cells incubated in pre- and post- dialysis plasma as a reporter system. Responses in cells incubated with pre- and post-dialysis uremic plasma (n = 10 were compared with responses elicited by plasma from control subjects (n = 5. The effects of adding IS to control plasma and of adding probenecid to uremic plasma were examined. Plasma concentrations of IS were measured by HPLC (high pressure liquid chromatography.Gene expression in our reporter system revealed dysregulation of 1912 genes in cells incubated with pre-dialysis uremic plasma. In cells incubated in post-dialysis plasma, the expression of 537 of those genes returned to baseline but the majority of them (1375 remained dysregulated. IS concentration was markedly elevated in pre- and post-dialysis plasma. Addition of IS to control plasma simulated more than 80% of the effects of uremic plasma on gene expression; the addition of probenecid, an organic anion transport (OAT inhibitor, to uremic plasma reversed the changes in gene expression.These findings provide evidence that hemodialysis fails to effectively clear one or more solutes that effect gene expression, in our reporter system, from the plasma of patients with uremia. The finding that gene dysregulation was simulated by the addition of IS to control plasma and inhibited by addition of an OAT inhibitor to uremic plasma identifies IS

  7. Genome-wide association study identifies novel locus for neuroticism and shows polygenic association with Major Depressive Disorder

    Science.gov (United States)

    de Moor, Marleen H.M.; van den Berg, Stéphanie M.; Verweij, Karin J.H.; Krueger, Robert F.; Luciano, Michelle; Vasquez, Alejandro Arias; Matteson, Lindsay K.; Derringer, Jaime; Esko, Tõnu; Amin, Najaf; Gordon, Scott D.; Hansell, Narelle K.; Hart, Amy B.; Seppälä, Ilkka; Huffman, Jennifer E.; Konte, Bettina; Lahti, Jari; Lee, Minyoung; Miller, Mike; Nutile, Teresa; Tanaka, Toshiko; Teumer, Alexander; Viktorin, Alexander; Wedenoja, Juho; Abecasis, Goncalo R.; Adkins, Daniel E.; Agrawal, Arpana; Allik, Jüri; Appel, Katja; Bigdeli, Timothy B.; Busonero, Fabio; Campbell, Harry; Costa, Paul T.; Smith, George Davey; Davies, Gail; de Wit, Harriet; Ding, Jun; Engelhardt, Barbara E.; Eriksson, Johan G.; Fedko, Iryna O.; Ferrucci, Luigi; Franke, Barbara; Giegling, Ina; Grucza, Richard; Hartmann, Annette M.; Heath, Andrew C.; Heinonen, Kati; Henders, Anjali K.; Homuth, Georg; Hottenga, Jouke-Jan; Janzing, Joost; Jokela, Markus; Karlsson, Robert; Kemp, John P.; Kirkpatrick, Matthew G.; Latvala, Antti; Lehtimäki, Terho; Liewald, David C.; Madden, Pamela A.F.; Magri, Chiara; Magnusson, Patrik K.E.; Marten, Jonathan; Maschio, Andrea; Medland, Sarah E.; Mihailov, Evelin; Milaneschi, Yuri; Montgomery, Grant W.; Nauck, Matthias; Ouwens, Klaasjan G.; Palotie, Aarno; Pettersson, Erik; Polasek, Ozren; Qian, Yong; Pulkki-Råback, Laura; Raitakari, Olli T.; Realo, Anu; Rose, Richard J.; Ruggiero, Daniela; Schmidt, Carsten O.; Slutske, Wendy S.; Sorice, Rossella; Starr, John M.; Pourcain, Beate St; Sutin, Angelina R.; Timpson, Nicholas J.; Trochet, Holly; Vermeulen, Sita; Vuoksimaa, Eero; Widen, Elisabeth; Wouda, Jasper; Wright, Margaret J.; Zgaga, Lina; Scotland, Generation; Porteous, David; Minelli, Alessandra; Palmer, Abraham A.; Rujescu, Dan; Ciullo, Marina; Hayward, Caroline; Rudan, Igor; Metspalu, Andres; Kaprio, Jaakko; Deary, Ian J.; Räikkönen, Katri; Wilson, James F.; Keltikangas-Järvinen, Liisa; Bierut, Laura J.; Hettema, John M.; Grabe, Hans J.; van Duijn, Cornelia M.; Evans, David M.; Schlessinger, David; Pedersen, Nancy L.; Terracciano, Antonio; McGue, Matt; Penninx, Brenda W.J.H.; Martin, Nicholas G.; Boomsma, Dorret I.

    2015-01-01

    Importance Neuroticism is a personality trait that is briefly defined by emotional instability. It is a robust genetic risk factor for Major Depressive Disorder (MDD) and other psychiatric disorders. Hence, neuroticism is an important phenotype for psychiatric genetics. The Genetics of Personality Consortium (GPC) has created a resource for genome-wide association analyses of personality traits in over 63,000 participants (including MDD cases). Objective To identify genetic variants associated with neuroticism by performing a meta-analysis of genome-wide association (GWA) results based on 1000Genomes imputation, to evaluate if common genetic variants as assessed by Single Nucleotide Polymorphisms (SNPs) explain variation in neuroticism by estimating SNP-based heritability, and to examine whether SNPs that predict neuroticism also predict MDD. Setting 30 cohorts with genome-wide genotype, personality and MDD data from the GPC. Participants The study included 63,661 participants from 29 discovery cohorts and 9,786 participants from a replication cohort. Participants came from Europe, the United States or Australia. Main outcome measure(s) Neuroticism scores harmonized across all cohorts by Item Response Theory (IRT) analysis, and clinically assessed MDD case-control status. Results A genome-wide significant SNP was found in the MAGI1 gene (rs35855737; P=9.26 × 10−9 in the discovery meta-analysis, and P=2.38 × 10−8 in the meta-analysis of all 30 cohorts). Common genetic variants explain 15% of the variance in neuroticism. Polygenic scores based on the meta-analysis of neuroticism in 27 of the discovery cohorts significantly predicted neuroticism in 2 independent cohorts. Importantly, polygenic scores also predicted MDD in these cohorts. Conclusions and relevance This study identifies a novel locus for neuroticism. The variant is located in a known gene that has been associated with bipolar disorder and schizophrenia in previous studies. In addition, the study

  8. Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A.

    Science.gov (United States)

    Beckers, Cora M L; Simpson, Kingsley R; Griffin, Kathryn J; Brown, Jane M; Cheah, Lih T; Smith, Kerrie A; Vacher, Jean; Cordell, Paul A; Kearney, Mark T; Grant, Peter J; Pease, Richard J

    2017-08-01

    To establish the cellular source of plasma factor (F)XIII-A. A novel mouse floxed for the F13a1 gene, FXIII-A flox/flox (Flox), was crossed with myeloid- and platelet-cre-expressing mice, and cellular FXIII-A mRNA expression and plasma and platelet FXIII-A levels were measured. The platelet factor 4-cre.Flox cross abolished platelet FXIII-A and reduced plasma FXIII-A to 23±3% ( P cre on plasma FXIII-A was exerted outside of the megakaryocyte lineage because plasma FXIII-A was not reduced in the Mpl -/- mouse, despite marked thrombocytopenia. In support of this, platelet factor 4-cre depleted FXIII-A mRNA in brain, aorta, and heart of floxed mice, where FXIII-A pos cells were identified as macrophages as they costained with CD163. In the integrin αM-cre.Flox and the double copy lysozyme 2-cre.cre.Flox crosses, plasma FXIII-A was reduced to, respectively, 75±5% ( P =0.003) and 30±7% ( P <0.001), with no change in FXIII-A content per platelet, further consistent with a macrophage origin of plasma FXIII-A. The change in plasma FXIII-A levels across the various mouse genotypes mirrored the change in FXIII-A mRNA expression in aorta. Bone marrow transplantation of FXIII-A +/+ bone marrow into FXIII-A -/- mice both restored plasma FXIII-A to normal levels and replaced aortic and cardiac FXIII-A mRNA, while its transplantation into FXIII-A +/+ mice did not increase plasma FXIII-A levels, suggesting that a limited population of niches exists that support FXIII-A-releasing cells. This work suggests that resident macrophages maintain plasma FXIII-A and exclude the platelet lineage as a major contributor. © 2017 The Authors.

  9. Utility of the PHQ-9 to identify major depressive disorder in adult patients in Spanish primary care centres.

    Science.gov (United States)

    Muñoz-Navarro, Roger; Cano-Vindel, Antonio; Medrano, Leonardo Adrián; Schmitz, Florian; Ruiz-Rodríguez, Paloma; Abellán-Maeso, Carmen; Font-Payeras, Maria Antonia; Hermosilla-Pasamar, Ana María

    2017-08-09

    The prevalence of major depressive disorder (MDD) in Spanish primary care (PC) centres is high. However, MDD is frequently underdiagnosed and consequently only some patients receive the appropriate treatment. The present study aims to determine the utility of the Patient Health Questionnaire-9 (PHQ-9) to identify MDD in a subset of PC patients participating in the large PsicAP study. A total of 178 patients completed the full PHQ test, including the depression module (PHQ-9). Also, a Spanish version of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) was implemented by clinical psychologists that were blinded to the PHQ-9 results. We evaluated the psychometric properties of the PHQ-9 as a screening tool as compared to the SCID-I as a reference standard. The psychometric properties of the PHQ-9 for a cut-off value of 10 points were as follows: sensitivity, 0.95; specificity, 0.67. Using a cut-off of 12 points, the values were: sensitivity, 0.84; specificity, 0.78. Finally, using the diagnostic algorithm for depression (DSM-IV criteria), the sensitivity was 0.88 and the specificity 0.80. As a screening instrument, the PHQ-9 performed better with a cut-off value of 12 versus the standard cut-off of 10. However, the best psychometric properties were obtained with the DSM-IV diagnostic algorithm for depression. These findings indicate that the PHQ-9 is a highly satisfactory tool that can be used for screening MDD in the PC setting. Current Controlled Trials ISRCTN58437086 . Registered 20 May 2013.

  10. Interaction Themes in Music Therapy

    DEFF Research Database (Denmark)

    Holck, Ulla

    2006-01-01

    Based on a doctoral study, the author presents a type of music therapy interaction called ‘Interaction Themes.’ These are developed from session to session and often appear in music therapy interventions with children with severe functional limitations, especially children with autism. Although...... whose expressions are often difficult to understand. The presented article describes the characteristics and functions of Interaction Themes, compares the phenomenon with music therapy case literature and delimits it in regard to other types of music therapy interaction with this client group....... the Interaction Themes are characterised by a relatively simple and self-generated content, they have an essential function because they contain the child’s and music therapist’s joint interaction history. They make up the context within which it is possible to create meaningful interaction with a client group...

  11. Interaction themes in music therapy

    DEFF Research Database (Denmark)

    Holck, Ulla

    2004-01-01

    Based on a doctoral study, the author presents a type of music therapyinteraction called ?Interaction Themes.? These are developed fromsession to session and often appear in music therapy interventions withchildren with severe functional limitations, especially children withautism. Although...... whoseexpressions are often difficult to understand. The article describes thecharacteristics and functions of Interaction Themes, compares thephenomenon with music therapy case literature and delimits it in regardto other types of music therapy interaction with this client group. Theresults are described through...... the Interaction Themes are characterised by arelatively simple and self-generated content, they have an essentialfunction because they contain the child?s and music therapist?s jointinteraction history. They make up the context within which it ispossible to create meaningful interaction with a client group...

  12. Identifying the Barriers upon Development of Virtual Education in Engineering Majors (Case Study: The University of Isfahan)

    Science.gov (United States)

    Nikoonezhad, Sepideh; Nili, Mohammadreza; Esfahani, Ahmadreza Nasr

    2015-01-01

    The present study aims at investigating barriers upon development of virtual education in engineering majors at the University of Isfahan. The study has applied a mixed method (qualitative and quantitative) and its population consists all of the department members of the technical and engineering majors at the University of Isfahan including 125…

  13. Recent Themes in Social Networking Service Research.

    Directory of Open Access Journals (Sweden)

    John S Liu

    Full Text Available The body of literature addressing the phenomenon related to social networking services (SNSs has grown rather fast recently. Through a systematic and quantitative approach, this study identifies the recent SNS research themes, which are the issues discussed by a coherent and growing subset of this literature. A set of academic articles retrieved from the Web of Science database is used as the basis for uncovering the recent themes. We begin the analysis by constructing a citation network which is further separated into groups after applying a widely used clustering method. The resulting clusters all consist of articles coherent in citation relationships. This study suggests eight fast growing recent themes. They span widely encompassing politics, romantic relationships, public relations, journalism, and health. Among them, four focus their issues largely on Twitter, three on Facebook, and one generally on both. While discussions on traditional issues in SNSs such as personality, motivations, self-disclosure, narcissism, etc. continue to lead the pack, the proliferation of the highlighted recent themes in the near future is very likely to happen.

  14. Recent Themes in Social Networking Service Research.

    Science.gov (United States)

    Liu, John S; Ho, Mei Hsiu-Ching; Lu, Louis Y Y

    2017-01-01

    The body of literature addressing the phenomenon related to social networking services (SNSs) has grown rather fast recently. Through a systematic and quantitative approach, this study identifies the recent SNS research themes, which are the issues discussed by a coherent and growing subset of this literature. A set of academic articles retrieved from the Web of Science database is used as the basis for uncovering the recent themes. We begin the analysis by constructing a citation network which is further separated into groups after applying a widely used clustering method. The resulting clusters all consist of articles coherent in citation relationships. This study suggests eight fast growing recent themes. They span widely encompassing politics, romantic relationships, public relations, journalism, and health. Among them, four focus their issues largely on Twitter, three on Facebook, and one generally on both. While discussions on traditional issues in SNSs such as personality, motivations, self-disclosure, narcissism, etc. continue to lead the pack, the proliferation of the highlighted recent themes in the near future is very likely to happen.

  15. Theme: Staying Current--Horticulture.

    Science.gov (United States)

    Shry, Carroll L., Jr.; And Others

    1986-01-01

    This theme issue on staying current in horticulture includes articles on sex equity in horticulture, Future Farmers of America, career opportunities in horticulture, staying current with your school district's needs, staying current in horticulture instruction, staying current with landscape trade associations, emphasizing the basics in vocational…

  16. BuddyPress theme development

    CERN Document Server

    Lister, Tammie

    2013-01-01

    This book is a hands-on tutorial guide to using BuddyPress.This book is great for designers and developers who are looking to learn how to develop BuddyPress themes. It's assumed that the reader has some understanding of Wordpress and is familiar with CSS and HTML.

  17. Accessing Transgenerational Themes Through Dreamwork.

    Science.gov (United States)

    Andrews, Jennifer; And Others

    1988-01-01

    Proposes use of dreamwork to evoke historical patterns or transgenerational themes. Describes new variant of dreamwork which combines aspects of both gestalt and family systems therapies. Implications of therapeutic dramatization for couple therapy are suggested. Examples are included. (Author/NB)

  18. A Framework for Mobile User Experiences in Theme Parks

    DEFF Research Database (Denmark)

    Østergaard, Claus Møller

    2013-01-01

    This paper proposes a framework, which contributes to a better theoretical understanding of mobile user experience in theme parks that is not limited to (a) personal smartphones, (b) a specific theme park, or (c) specific mobile content. Thus, the paper contributes to the field of mobile user...... experience in theme parks within HCI. The identified aspects constituting the mobile user experience in theme parks are the environmental context, the social context, the functional context, the mobile interface, and of course the mobile content. The framework is developed based on five diverse case studies...

  19. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

    DEFF Research Database (Denmark)

    Deelen, Joris; Beekman, Marian; Uh, Hae-Won

    2011-01-01

    By studying the loci which contribute to human longevity, we aim to identify mechanisms that contribute to healthy aging. To identify such loci, we performed a genome-wide association study (GWAS) comparing 403 unrelated nonagenarians from long-living families included in the Leiden Longevity Stu...

  20. Proteomic analysis identifies mitochondrial metabolic enzymes as major discriminators between different stages of the failing human myocardium

    DEFF Research Database (Denmark)

    Urbonavicius, Sigitas; Wiggers, Henrik; Bøtker, Hans Erik

    2009-01-01

    Our aim was to identify patterns in differentially regulated proteins associated with the progression of chronic heart failure. We specifically studied proteomics in chronic reversibly (RDM) and irreversibly dysfunctional myocardium (IRDM), as well as end-stage failing myocardium (ESFM).......Our aim was to identify patterns in differentially regulated proteins associated with the progression of chronic heart failure. We specifically studied proteomics in chronic reversibly (RDM) and irreversibly dysfunctional myocardium (IRDM), as well as end-stage failing myocardium (ESFM)....

  1. Spring Framework 5: Themes & Trends

    CERN Document Server

    CERN. Geneva

    2017-01-01

    Spring Framework 5.0/5.1, scheduled for release in early/late 2017, focuses on several key themes: reactive web applications based on Reactive Streams, comprehensive support for JDK 9 and HTTP/2, as well as the latest API generations in the Enterprise Java ecosystem. This talk presents the overall story in the context of wider industry trends, highlighting Spring’s unique programming model strategy.

  2. Essential themes in Personnel economics

    OpenAIRE

    Josheski, Dushko

    2014-01-01

    In this paper are presented essential themes in the subject of personnel economics. In the first part analysis has been conducted on the impact of peer pressure on workplace behaviour. Then again models for compensation structures within firms, and their influence on the utility of work by employees. In the final section of the paper the productivity spillover effect has been analyzed, and the causes of existence of spillovers and their impact on workers’ productivity

  3. Thirty years of artificial intelligence in medicine (AIME) conferences: A review of research themes.

    Science.gov (United States)

    Peek, Niels; Combi, Carlo; Marin, Roque; Bellazzi, Riccardo

    2015-09-01

    Over the past 30 years, the international conference on Artificial Intelligence in MEdicine (AIME) has been organized at different venues across Europe every 2 years, establishing a forum for scientific exchange and creating an active research community. The Artificial Intelligence in Medicine journal has published theme issues with extended versions of selected AIME papers since 1998. To review the history of AIME conferences, investigate its impact on the wider research field, and identify challenges for its future. We analyzed a total of 122 session titles to create a taxonomy of research themes and topics. We classified all 734 AIME conference papers published between 1985 and 2013 with this taxonomy. We also analyzed the citations to these conference papers and to 55 special issue papers. We identified 30 research topics across 12 themes. AIME was dominated by knowledge engineering research in its first decade, while machine learning and data mining prevailed thereafter. Together these two themes have contributed about 51% of all papers. There have been eight AIME papers that were cited at least 10 times per year since their publication. There has been a major shift from knowledge-based to data-driven methods while the interest for other research themes such as uncertainty management, image and signal processing, and natural language processing has been stable since the early 1990s. AIME papers relating to guidelines and protocols are among the most highly cited. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Violence and family bounds in Phaedra's theme

    OpenAIRE

    Soares, Filipe

    2016-01-01

    UID/HIS/04666/2013 In World Culture love is presented as one the major topics explored by its intervenients. Concerning our study, it presents love and sexuality in terms of its disruptiveness: they are characterized as a force that destabilizes the status quo of human communities, leading to situations of Love/ Violence and Love/ Death. From this point of view, the Theme of Phaedra (after Thompson‟s Motif-Index) can be analysed in this perspective. Its variations allow him to adapt to dif...

  5. Using Statistical Process Control Charts to Identify the Steroids Era in Major League Baseball: An Educational Exercise

    Science.gov (United States)

    Hill, Stephen E.; Schvaneveldt, Shane J.

    2011-01-01

    This article presents an educational exercise in which statistical process control charts are constructed and used to identify the Steroids Era in American professional baseball. During this period (roughly 1993 until the present), numerous baseball players were alleged or proven to have used banned, performance-enhancing drugs. Also observed…

  6. Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes

    NARCIS (Netherlands)

    Pillai, S. G.; Tang, Y.; van den Oord, E.; Klotsman, M.; Barnes, K.; Carlsen, K.; Gerritsen, J.; Lenney, W.; Silverman, M.; Sly, P.; Sundy, J.; Tsanakas, J.; von Berg, A.; Whyte, M.; Ortega, H. G.; Anderson, W. H.; Helms, P. J.

    Background Asthma is a clinically heterogeneous disease caused by a complex interaction between genetic susceptibility and diverse environmental factors. In common with other complex diseases the lack of a standardized scheme to evaluate the phenotypic variability poses challenges in identifying the

  7. Neuroleadership: Themes and limitations of an emerging interdisciplinary field.

    Science.gov (United States)

    Kuhlmann, Naila; Kadgien, Chelsie A

    2018-05-01

    The relationship between brain and behaviour has perplexed philosophers and scientists since the time of the ancient Greeks. Recent technological advances have allowed neuroscience to flourish, alongside growing romanticism that reductionist studies will allow us to understand complex interpersonal behaviours. Organizational cognitive neuroscience and neuroleadership are newly established interdisciplinary fields that use neuroscientific techniques to answer questions about behaviours within organizations. Neuroleadership aims to discover screening tools for good leaders, to improve leadership skills, and to identify unconscious factors affecting behaviour in hopes of improving management and leadership practices. Although proponents of neuroleadership are optimistic, if we know anything about the functions of the human brain and our interpersonal behaviours, it is that they are exquisitely complex and context dependant. Here, we briefly discuss the major themes emerging in the new field of neuroleadership and the limitations and potential consequences of applying findings from the field prematurely and with blind optimism.

  8. Next Generation Sequencing Identifies Five Major Classes of Potentially Therapeutic Enzymes Secreted by Lucilia sericata Medical Maggots.

    Science.gov (United States)

    Franta, Zdeněk; Vogel, Heiko; Lehmann, Rüdiger; Rupp, Oliver; Goesmann, Alexander; Vilcinskas, Andreas

    2016-01-01

    Lucilia sericata larvae are used as an alternative treatment for recalcitrant and chronic wounds. Their excretions/secretions contain molecules that facilitate tissue debridement, disinfect, or accelerate wound healing and have therefore been recognized as a potential source of novel therapeutic compounds. Among the substances present in excretions/secretions various peptidase activities promoting the wound healing processes have been detected but the peptidases responsible for these activities remain mostly unidentified. To explore these enzymes we applied next generation sequencing to analyze the transcriptomes of different maggot tissues (salivary glands, gut, and crop) associated with the production of excretions/secretions and/or with digestion as well as the rest of the larval body. As a result we obtained more than 123.8 million paired-end reads, which were assembled de novo using Trinity and Oases assemblers, yielding 41,421 contigs with an N50 contig length of 2.22 kb and a total length of 67.79 Mb. BLASTp analysis against the MEROPS database identified 1729 contigs in 577 clusters encoding five peptidase classes (serine, cysteine, aspartic, threonine, and metallopeptidases), which were assigned to 26 clans, 48 families, and 185 peptidase species. The individual enzymes were differentially expressed among maggot tissues and included peptidase activities related to the therapeutic effects of maggot excretions/secretions.

  9. The role of tobacco advertising and promotion: themes employed in litigation by tobacco industry witnesses.

    Science.gov (United States)

    Goldberg, Marvin E; Davis, Ronald M; O'Keefe, Anne Marie

    2006-12-01

    To identify key themes related to tobacco advertising and promotion in testimony provided by tobacco industry-affiliated witnesses in tobacco litigation, and to present countervailing evidence and arguments. Themes in industry testimony were identified by review of transcripts of testimony in the Tobacco Deposition and Trial Testimony Archive (http://tobaccodocuments.org/datta) from a sample of defence witnesses, including three academic expert witnesses, six senior executives of tobacco companies, and one industry advertising consultant. Counterarguments to the themes embodied in defence testimony were based on information from peer-reviewed literature, advertising trade publications, government reports, tobacco industry documents, and testimony provided by expert witnesses testifying for plaintiffs. Five major themes employed by defence witnesses were identified: (1) tobacco advertising has a relatively weak "share of voice" in the marketing environment and is a weak force in affecting smoking behaviour; (2) tobacco advertising and promotion do not create new smokers, expand markets, or increase total tobacco consumption; (3) the tobacco industry does not target, study, or track youth smoking; (4) tobacco advertising and promotion do not cause smoking initiation by youth; and (5) tobacco companies and the industry adhere closely to relevant laws, regulations, and industry voluntary codes. Substantial evidence exists in rebuttal to these arguments. Tobacco industry-affiliated witnesses have marshalled many arguments to deny the adverse effects of tobacco marketing activities and to portray tobacco companies as responsible corporate citizens. Effective rebuttals to these arguments exist, and plaintiffs' attorneys have, with varying degrees of success, presented them to judges and juries.

  10. Tropomyosin and Actin Identified as Major Allergens of the Carpet Clam (Paphia textile and the Effect of Cooking on Their Allergenicity

    Directory of Open Access Journals (Sweden)

    Zailatul Hani Mohamad Yadzir

    2015-01-01

    Full Text Available Objectives. To identify the major allergenic proteins of clam (Paphia textile and to investigate the effect of different cooking methods on the allergenicity of these identified proteins. Methods. Clam protein extracts were separated by denaturing polyacrylamide gel electrophoresis. IgE reactive proteins were then analyzed by immunoblotting with sera from patients with positive skin prick tests (SPT to the raw clam extract. Mass spectrometry was used to identify the major allergenic proteins of this clam. Results. Raw extract showed 12 protein bands (18–150 kDa. In contrast, fewer protein bands were seen in the boiled extract; those ranging from 40 to 150 kDa were denatured. The protein profiles were similarly altered by frying or roasting. The immunoblots of raw and boiled extracts yielded 10 and 2 IgE-binding proteins, respectively. The fried and roasted extracts showed only a single IgE-binding protein at 37 kDa. Mass spectrometry analysis of the 37 and 42 kDa major allergens indicated that these spots were tropomyosin and actin, respectively. Conclusion. The two major allergens of Paphia textile were identified as the thermostable tropomyosin and a new thermolabile allergen actin.

  11. Changes in themes over time from medical student journaling.

    Science.gov (United States)

    Cayley, William; Schilling, Rae; Suechting, Ralph

    2007-12-01

    There has been little exploration of journaling in medical student education. To document the themes on which medical students reflect during training. We evaluated journals kept by primary care medical students to identify prominent themes and determine change or constancy in themes over time. We looked at third-year medical students participating in a required primary care clerkship in a university-affiliated, community-based family medicine residency program with a rural catchment area. During 1994-1996 and 2001-2003, students were asked to keep weekly journals reflecting on their thoughts and feelings regarding "topical content, course processes and methods, and personal reflections on becoming a doctor." Faculty evaluated journals to identify change or constancy in themes over time. Prominent themes included gender issues, professional identity emergence, career choice, and rural practice, the experience of learning, the experience of relating to patients, and the nature of medical practice. We found both constancy and change in student journal themes over time. Changes in journal themes appeared to correlate with outside events and educational trends, including increased attention to reflective practice, changing demographics in medicine and the increasing acceptance of female physicians, and personal life events.

  12. Mercosur's regional health agenda: architecture and themes

    Directory of Open Access Journals (Sweden)

    Luisa Guimaraes Queiroz

    Full Text Available This article describes the shaping of institutional health spaces in the Mercosur, with analysis of themes and results and considerations on the construction of the regional agenda and on the effects of regional economic integration processes on health policies and systems. We discuss the organization, operation, focus topics, and results achieved in specific health forums (Meeting of Ministers of Health and Sub-Working Group 11, seeking to analyze the architecture and issues addressed by the regional agenda and drawing parallels with the European experience. The aim of this reflection is to identify how the work done by Mercosur structures contributes to building a regional agenda, with the expectation that the integration can contribute to reducing inequalities in access to health care in the region.

  13. Chameleon Changes: An Exploration of Racial Identity Themes of Multiracial People

    Science.gov (United States)

    Miville, Marie L.; Constantine, Madonna G.; Baysden, Matthew F.; So-Lloyd, Gloria

    2005-01-01

    The current study explored essential themes of racial identity development among 10 self-identified multiracial adults from a variety of racial backgrounds. Participants were interviewed using a semistructured protocol, and the interviews were recorded, transcribed, and then coded for themes by research team members. Four primary themes were…

  14. Societal acceptance of wind farms: Analysis of four common themes across Australian case studies

    International Nuclear Information System (INIS)

    Hall, N.; Ashworth, P.; Devine-Wright, P.

    2013-01-01

    Australia's renewable energy target (RET) seeks to provide 20 per cent of Australia's electricity generation from renewable energy sources by 2020. As wind power is relatively advanced, it was anticipated that wind power will contribute a major component of the early target. However, high levels of societal resistance to wind farms, combined with new regulatory policies, indicate the RET may not be dominated by wind power. This research involved an examination of seven case studies around wind farm deployment. Qualitative interviews were the primary data for the case studies and analysed using methods informed by grounded theory. Despite the diversity of stakeholder views, the qualitative analysis identified strong community support for wind farms but four common themes emerged that influence this societal acceptance of wind farms in Australia: trust, distributional justice, procedural justice and place attachment. Without addressing these factors through integration into policy development and engagement approaches, wind energy is unlikely to provide the early and majority of new renewable energy. Similar international experiences are incorporated in the discussion of the Australian wind industry's societal acceptance. - Highlights: ► Seven case studies of wind farms in Australia are described. ► Acceptance affects whether wind significantly contributes to the Aust. RE target. ► Four themes were identified regarding societal acceptance of Australian wind farms. ► Four themes are trust, distributional and procedural justice, and place attachment. ► International similarities to the Australian experience are provided

  15. Integrated pathway clusters with coherent biological themes for target prioritisation.

    Directory of Open Access Journals (Sweden)

    Yi-An Chen

    Full Text Available Prioritising candidate genes for further experimental characterisation is an essential, yet challenging task in biomedical research. One way of achieving this goal is to identify specific biological themes that are enriched within the gene set of interest to obtain insights into the biological phenomena under study. Biological pathway data have been particularly useful in identifying functional associations of genes and/or gene sets. However, biological pathway information as compiled in varied repositories often differs in scope and content, preventing a more effective and comprehensive characterisation of gene sets. Here we describe a new approach to constructing biologically coherent gene sets from pathway data in major public repositories and employing them for functional analysis of large gene sets. We first revealed significant overlaps in gene content between different pathways and then defined a clustering method based on the shared gene content and the similarity of gene overlap patterns. We established the biological relevance of the constructed pathway clusters using independent quantitative measures and we finally demonstrated the effectiveness of the constructed pathway clusters in comparative functional enrichment analysis of gene sets associated with diverse human diseases gathered from the literature. The pathway clusters and gene mappings have been integrated into the TargetMine data warehouse and are likely to provide a concise, manageable and biologically relevant means of functional analysis of gene sets and to facilitate candidate gene prioritisation.

  16. Genome-wide transcriptome study in wheat identified candidate genes related to processing quality, majority of them showing interaction (quality x development) and having temporal and spatial distributions.

    Science.gov (United States)

    Singh, Anuradha; Mantri, Shrikant; Sharma, Monica; Chaudhury, Ashok; Tuli, Rakesh; Roy, Joy

    2014-01-16

    The cultivated bread wheat (Triticum aestivum L.) possesses unique flour quality, which can be processed into many end-use food products such as bread, pasta, chapatti (unleavened flat bread), biscuit, etc. The present wheat varieties require improvement in processing quality to meet the increasing demand of better quality food products. However, processing quality is very complex and controlled by many genes, which have not been completely explored. To identify the candidate genes whose expressions changed due to variation in processing quality and interaction (quality x development), genome-wide transcriptome studies were performed in two sets of diverse Indian wheat varieties differing for chapatti quality. It is also important to understand the temporal and spatial distributions of their expressions for designing tissue and growth specific functional genomics experiments. Gene-specific two-way ANOVA analysis of expression of about 55 K transcripts in two diverse sets of Indian wheat varieties for chapatti quality at three seed developmental stages identified 236 differentially expressed probe sets (10-fold). Out of 236, 110 probe sets were identified for chapatti quality. Many processing quality related key genes such as glutenin and gliadins, puroindolines, grain softness protein, alpha and beta amylases, proteases, were identified, and many other candidate genes related to cellular and molecular functions were also identified. The ANOVA analysis revealed that the expression of 56 of 110 probe sets was involved in interaction (quality x development). Majority of the probe sets showed differential expression at early stage of seed development i.e. temporal expression. Meta-analysis revealed that the majority of the genes expressed in one or a few growth stages indicating spatial distribution of their expressions. The differential expressions of a few candidate genes such as pre-alpha/beta-gliadin and gamma gliadin were validated by RT-PCR. Therefore, this study

  17. Genome-wide transcriptome study in wheat identified candidate genes related to processing quality, majority of them showing interaction (quality x development) and having temporal and spatial distributions

    Science.gov (United States)

    2014-01-01

    Background The cultivated bread wheat (Triticum aestivum L.) possesses unique flour quality, which can be processed into many end-use food products such as bread, pasta, chapatti (unleavened flat bread), biscuit, etc. The present wheat varieties require improvement in processing quality to meet the increasing demand of better quality food products. However, processing quality is very complex and controlled by many genes, which have not been completely explored. To identify the candidate genes whose expressions changed due to variation in processing quality and interaction (quality x development), genome-wide transcriptome studies were performed in two sets of diverse Indian wheat varieties differing for chapatti quality. It is also important to understand the temporal and spatial distributions of their expressions for designing tissue and growth specific functional genomics experiments. Results Gene-specific two-way ANOVA analysis of expression of about 55 K transcripts in two diverse sets of Indian wheat varieties for chapatti quality at three seed developmental stages identified 236 differentially expressed probe sets (10-fold). Out of 236, 110 probe sets were identified for chapatti quality. Many processing quality related key genes such as glutenin and gliadins, puroindolines, grain softness protein, alpha and beta amylases, proteases, were identified, and many other candidate genes related to cellular and molecular functions were also identified. The ANOVA analysis revealed that the expression of 56 of 110 probe sets was involved in interaction (quality x development). Majority of the probe sets showed differential expression at early stage of seed development i.e. temporal expression. Meta-analysis revealed that the majority of the genes expressed in one or a few growth stages indicating spatial distribution of their expressions. The differential expressions of a few candidate genes such as pre-alpha/beta-gliadin and gamma gliadin were validated by RT

  18. Transcriptional Profiling of Hypoxic Neural Stem Cells Identifies Calcineurin-NFATc4 Signaling as a Major Regulator of Neural Stem Cell Biology

    Science.gov (United States)

    Moreno, Marta; Fernández, Virginia; Monllau, Josep M.; Borrell, Víctor; Lerin, Carles; de la Iglesia, Núria

    2015-01-01

    Summary Neural stem cells (NSCs) reside in a hypoxic microenvironment within the brain. However, the crucial transcription factors (TFs) that regulate NSC biology under physiologic hypoxia are poorly understood. Here we have performed gene set enrichment analysis (GSEA) of microarray datasets from hypoxic versus normoxic NSCs with the aim of identifying pathways and TFs that are activated under oxygen concentrations mimicking normal brain tissue microenvironment. Integration of TF target (TFT) and pathway enrichment analysis identified the calcium-regulated TF NFATc4 as a major candidate to regulate hypoxic NSC functions. Nfatc4 expression was coordinately upregulated by top hypoxia-activated TFs, while NFATc4 target genes were enriched in hypoxic NSCs. Loss-of-function analyses further revealed that the calcineurin-NFATc4 signaling axis acts as a major regulator of NSC self-renewal and proliferation in vitro and in vivo by promoting the expression of TFs, including Id2, that contribute to the maintenance of the NSC state. PMID:26235896

  19. Exploring Multicultural Themes through Picture Books.

    Science.gov (United States)

    Farris, Pamela J.

    1995-01-01

    Advocates inclusion of multicultural picture books in social studies instruction to offer different outlooks and visions in a short format. Describes selection of picture books with multicultural themes and those that represent various cultures, gender equity, and religious themes. Suggests that picture books may help students develop better…

  20. Themes and Interplay of Beliefs in Mathematical Reasoning

    Science.gov (United States)

    Sumpter, Lovisa

    2013-01-01

    Upper secondary students' task solving reasoning was analysed with a focus on arguments for strategy choices and conclusions. Passages in their arguments for reasoning that indicated the students' beliefs were identified and, by using a thematic analysis, categorized. The results stress three themes of beliefs used as arguments for…

  1. Picking up the Pieces: Themes in Macedonian Midcareer Transitions

    Science.gov (United States)

    Sudnik, Paul

    2012-01-01

    Addressing midcareer transition in post-socialist Macedonia, this work sought to provide practical help to participants through a range of techniques. Four themes are identified as important options for transitioners. Enthusiasm for "entrepreneurship" is tempered by a lack of funds and "portfolio careers" are also viewed with…

  2. Trends in Literacy Software Publication and Marketing: Multicultural Themes.

    Science.gov (United States)

    Balajthy, Ernest

    This article provides data and discussion of multicultural theme-related issues arising from analysis of a detailed database of commercial software products targeted to reading and literacy education. The database consisted of 1152 titles, representing the offerings of 104 publishers and distributors. Of the titles, 62 were identified as having…

  3. Themes addressed by couples with advanced cancer during a communication skills training intervention.

    Science.gov (United States)

    Porter, Laura S; Fish, Laura; Steinhauser, Karen

    2018-04-25

    Couple-based communication interventions have beneficial effects for patients with cancer and their partners. However, few studies have targeted patients with advanced stages of disease and little is known about how best to assist couples in discussing issues related to life-limiting illness. The purpose of the present study was to identify themes couples addressed during a couple communication skills intervention, and the frequency with which they discussed issues related to end-of-life. Content analyses were conducted on recordings of 72 sessions from 12 couples facing advanced gastrointestinal (GI) cancer. Coding was based six themes identified a priori from the framework for understanding what patients and family value at end of life. The percent of couples addressing each theme was calculated to gauge level of importance and acceptability of these topics. The majority of couples addressed topics previously identified as salient at end-of-life, including clear decision making, affirmation of the whole person, pain and symptom management, contributing to others, and preparation for death. In addition, novel aspects to these themes emerged in the context of couples' conversations, illustrating the importance of the couple relationship in adjusting to life with a life-limiting illness and anticipating the transition to end-of-life. Findings suggest that couples likely would be receptive to an intervention that combines training in communication skills with guidance in focusing on issues related to life completion to assist with transitions at end of life. Such interventions might enhance both individuals' abilities to cope with illness-related symptoms and demands, enjoy the time they have together, and derive meaning from the experience. Copyright © 2018. Published by Elsevier Inc.

  4. Isolation of cDNA encoding a newly identified major allergenic protein of rye-grass pollen: intracellular targeting to the amyloplast.

    Science.gov (United States)

    Singh, M B; Hough, T; Theerakulpisut, P; Avjioglu, A; Davies, S; Smith, P M; Taylor, P; Simpson, R J; Ward, L D; McCluskey, J

    1991-01-01

    We have identified a major allergenic protein from rye-grass pollen, tentatively designated Lol pIb of 31kDa and with pI 9.0. A cDNA clone encoding Lol pIb has been isolated, sequenced, and characterized. Lol pIb is located mainly in the starch granules. This is a distinct allergen from Lol pI, which is located in the cytosol. Lol pIb is synthesized in pollen as a pre-allergen with a transit peptide targeting the allergen to amyloplasts. Epitope mapping of the fusion protein localized the IgE binding determinant in the C-terminal domain. Images PMID:1671715

  5. Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

    Science.gov (United States)

    Miller, F W; Chen, W; O'Hanlon, T P; Cooper, R G; Vencovsky, J; Rider, L G; Danko, K; Wedderburn, L R; Lundberg, I E; Pachman, L M; Reed, A M; Ytterberg, S R; Padyukov, L; Selva-O'Callaghan, A; Radstake, T R; Isenberg, D A; Chinoy, H; Ollier, W E R; Scheet, P; Peng, B; Lee, A; Byun, J; Lamb, J A; Gregersen, P K; Amos, C I

    2015-10-01

    Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic and environmental factors. To identify genetic risk factors in patients of European ancestry, we conducted a genome-wide association study (GWAS) of the major myositis phenotypes in a total of 1710 cases, which included 705 adult dermatomyositis, 473 juvenile dermatomyositis, 532 polymyositis and 202 adult dermatomyositis, juvenile dermatomyositis or polymyositis patients with anti-histidyl-tRNA synthetase (anti-Jo-1) autoantibodies, and compared them with 4724 controls. Single-nucleotide polymorphisms showing strong associations (Pmyositis phenotypes together, as well as for the four clinical and autoantibody phenotypes studied separately. Imputation and regression analyses found that alleles comprising the human leukocyte antigen (HLA) 8.1 ancestral haplotype (AH8.1) defined essentially all the genetic risk in the phenotypes studied. Although the HLA DRB1*03:01 allele showed slightly stronger associations with adult and juvenile dermatomyositis, and HLA B*08:01 with polymyositis and anti-Jo-1 autoantibody-positive myositis, multiple alleles of AH8.1 were required for the full risk effects. Our findings establish that alleles of the AH8.1 comprise the primary genetic risk factors associated with the major myositis phenotypes in geographically diverse Caucasian populations.

  6. Prokaryotic Argonautes - variations on the RNA interference theme

    Science.gov (United States)

    van der Oost, John; Swarts, Daan C.; Jore, Matthijs M.

    2014-01-01

    The discovery of RNA interference (RNAi) has been a major scientific breakthrough. This RNA-guided RNA interference system plays a crucial role in a wide range of regulatory and defense mechanisms in eukaryotes. The key enzyme of the RNAi system is Argonaute (Ago), an endo-ribonuclease that uses a small RNA guide molecule to specifically target a complementary RNA transcript. Two functional classes of eukaryotic Ago have been described: catalytically active Ago that cleaves RNA targets complementary to its guide, and inactive Ago that uses its guide to bind target RNA to down-regulate translation efficiency. A recent comparative genomics study has revealed that Argonaute-like proteins are also encoded by prokaryotic genomes. Interestingly, there is a lot of variation among these prokaryotic Argonaute (pAgo) proteins with respect to domain architecture: some resemble the eukaryotic Ago (long pAgo) containing a complete or disrupted catalytic site, while others are truncated versions (short pAgo) that generally contain an incomplete catalytic site. Prokaryotic Agos with an incomplete catalytic site often co-occur with (predicted) nucleases. Based on this diversity, and on the fact that homologs of other RNAi-related protein components (such as Dicer nucleases) have never been identified in prokaryotes, it has been predicted that variations on the eukaryotic RNAi theme may occur in prokaryotes. PMID:28357239

  7. A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.

    Directory of Open Access Journals (Sweden)

    Matteo Bianchi

    Full Text Available Hypothyroidism is a complex clinical condition found in both humans and dogs, thought to be caused by a combination of genetic and environmental factors. In this study we present a multi-breed analysis of predisposing genetic risk factors for hypothyroidism in dogs using three high-risk breeds--the Gordon Setter, Hovawart and the Rhodesian Ridgeback. Using a genome-wide association approach and meta-analysis, we identified a major hypothyroidism risk locus shared by these breeds on chromosome 12 (p = 2.1x10(-11. Further characterisation of the candidate region revealed a shared ~167 kb risk haplotype (4,915,018-5,081,823 bp, tagged by two SNPs in almost complete linkage disequilibrium. This breed-shared risk haplotype includes three genes (LHFPL5, SRPK1 and SLC26A8 and does not extend to the dog leukocyte antigen (DLA class II gene cluster located in the vicinity. These three genes have not been identified as candidate genes for hypothyroid disease previously, but have functions that could potentially contribute to the development of the disease. Our results implicate the potential involvement of novel genes and pathways for the development of canine hypothyroidism, raising new possibilities for screening, breeding programmes and treatments in dogs. This study may also contribute to our understanding of the genetic etiology of human hypothyroid disease, which is one of the most common endocrine disorders in humans.

  8. Deep sequencing of Salmonella RNA associated with heterologous Hfq proteins in vivo reveals small RNAs as a major target class and identifies RNA processing phenotypes.

    Science.gov (United States)

    Sittka, Alexandra; Sharma, Cynthia M; Rolle, Katarzyna; Vogel, Jörg

    2009-01-01

    The bacterial Sm-like protein, Hfq, is a key factor for the stability and function of small non-coding RNAs (sRNAs) in Escherichia coli. Homologues of this protein have been predicted in many distantly related organisms yet their functional conservation as sRNA-binding proteins has not entirely been clear. To address this, we expressed in Salmonella the Hfq proteins of two eubacteria (Neisseria meningitides, Aquifex aeolicus) and an archaeon (Methanocaldococcus jannaschii), and analyzed the associated RNA by deep sequencing. This in vivo approach identified endogenous Salmonella sRNAs as a major target of the foreign Hfq proteins. New Salmonella sRNA species were also identified, and some of these accumulated specifically in the presence of a foreign Hfq protein. In addition, we observed specific RNA processing defects, e.g., suppression of precursor processing of SraH sRNA by Methanocaldococcus Hfq, or aberrant accumulation of extracytoplasmic target mRNAs of the Salmonella GcvB, MicA or RybB sRNAs. Taken together, our study provides evidence of a conserved inherent sRNA-binding property of Hfq, which may facilitate the lateral transmission of regulatory sRNAs among distantly related species. It also suggests that the expression of heterologous RNA-binding proteins combined with deep sequencing analysis of RNA ligands can be used as a molecular tool to dissect individual steps of RNA metabolism in vivo.

  9. An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

    Directory of Open Access Journals (Sweden)

    Alex Clop

    Full Text Available Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS have identified 36 disease susceptibility regions, more than 50% of the genetic variance can be attributed to a single Major Histocompatibility Complex (MHC locus, known as PSORS1. Genetic studies indicate that HLA-C is the strongest PSORS1 candidate gene, since markers tagging HLA-Cw*0602 consistently generate the most significant association signals in GWAS. However, it is unclear whether HLA-Cw*0602 is itself the causal PSORS1 allele, especially as the role of SNPs that may affect its expression has not been investigated. Here, we have undertaken an in-depth molecular characterization of the PSORS1 interval, with a view to identifying regulatory variants that may contribute to disease susceptibility. By analysing high-density SNP data, we refined PSORS1 to a 179 kb region encompassing HLA-C and the neighbouring HCG27 pseudogene. We compared multiple MHC sequences spanning this refined locus and identified 144 candidate susceptibility variants, which are unique to chromosomes bearing HLA-Cw*0602. In parallel, we investigated the epigenetic profile of the critical PSORS1 interval and uncovered three enhancer elements likely to be active in T lymphocytes. Finally we showed that nine candidate susceptibility SNPs map within a HLA-C enhancer and that three of these variants co-localise with binding sites for immune-related transcription factors. These data indicate that SNPs affecting HLA-Cw*0602 expression are likely to contribute to psoriasis susceptibility and highlight the importance of integrating multiple experimental approaches in the investigation of complex genomic regions such as the MHC.

  10. On the emergence theme of physics

    CERN Document Server

    Carroll, Robert

    2010-01-01

    The book surveys mathematical relations between classical and quantum mechanics, gravity, time and thermodynamics from various points of view and many sources (with appropriate attribution). The emergence theme is developed with an emphasis on the meaning via mathematics. A background theme of Bohemian mechanics and connections to the quantum equivalence principle of Matone et al. is also developed in great detail. Some original work relating the quantum potential and Ricci flow is also included.

  11. Future Research Themes in Supply Chain Management

    DEFF Research Database (Denmark)

    Wieland, Andreas

    2016-01-01

    Guest post on research results published in the article "Mapping the Landscape of Future Research Themes in Supply Chain Management" by Andreas Wieland, Robert Handfield and Christian Durach ( Journal of Business Logistics (2016). Vol. 37, no. 3, pp. 205-212).......Guest post on research results published in the article "Mapping the Landscape of Future Research Themes in Supply Chain Management" by Andreas Wieland, Robert Handfield and Christian Durach ( Journal of Business Logistics (2016). Vol. 37, no. 3, pp. 205-212)....

  12. Child injury control: trends, themes, and controversies.

    Science.gov (United States)

    Johnston, Brian D; Ebel, Beth E

    2013-01-01

    Injury is a major cause of morbidity and mortality among US children, and an important driver of health status globally. Despite its enormous burden, injury is preventable. Over the last 10 years, significant progress has been made in the reduction of unintentional injury among US children. However, aggregate trends mask important disparities by age group, region, and injury mechanism. Basic and translation research is needed to develop and test prevention strategies to address these new or recalcitrant problems. Motor vehicle occupant injury has fallen to historic lows, but challenges remain in protecting novice drivers and managing the distraction of new technologies. Injury to pedestrians has also declined, but likely as a result of decreased exposure as fewer children walk. This calls for a broader public health perspective to promote activity while enhancing safety. Deaths due to drowning are common and illustrate the difficulty in measuring and promoting appropriate supervision. Environmental modification and use of protective products may be a more appropriate response. Concussion in sport is another challenging issue: public health laws promote identification and appropriate management of concussed athletes, but less progress has been made on primary prevention of these injuries. Unintentional poisoning is on the rise, attributable to misuse of, and overdose with, prescription opioids. Injury deaths to infants are also increasing. This trend is driven in part by better death investigation that classifies more sleep-related deaths as suffocation events. Finally, we examine a sample of cross-cutting themes and controversies in injury control that might be amenable to empiric evaluation. Copyright © 2013 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  13. Bibliography of Papers Published in the Journal Migration Themes / Migration and Ethnic Themes (1985 – 2014

    Directory of Open Access Journals (Sweden)

    Sanja Klempić Bogadi

    2015-04-01

    shifted toward new phenomena and processes throughout the world such as globalization, increasing spatial mobility of people, and delocalisation and relocalisation of culture. In line with these topics, we have decided to classify the published papers into the following major thematic groups: 1. Migration, 2. Ethnicity, 3. Population, 4. Bibliographies, and 5. Other, whereby the first three groups are divided into subgroups. Taking into consideration the fact that the papers deal with various aspects of migration, ethnicity and identity, and part of them belong to two or even three basic groups at the same time, it has been impossible to assign them to only one of them. The papers whose themes are somewhat different and cannot be included in any of the mentioned groups, are classified in the group Other. The bibliography was compiled by the de visu method, that is, by checking the physical copies of the journal. Within the specific groups, the papers are listed in alphabetical order by the authors’ last names. In the case of several papers pertaining to the same author within the same subgroup, they are arranged chronologically, starting with the earliest. Each bibliographical entry contains the following information: last name, first name, title, volume, year, number and range of pages. The bibliography has an author’s index. The authors’ names in the index are linked with the number of the bibliographical entry, and are listed as they are cited in the journal so that the versions of the names or last names of the same author are placed one after the other. The papers that are classified into two or three basic groups are marked both bold and plain, with the numbers in bold denoting bibliographical records in which such papers appear for the first time and, at the same time, show the number of papers of a particular author.

  14. Age-Graded Themes in White American Middle-Class Slang: A Hypothesis.

    Science.gov (United States)

    Donahue, Thomas S.

    It is proposed that middle- and upper-middle-class slang used among white young people in modern America shows age-related themes. For youngsters between the ages of eight and early adolescence, the major theme in slang use is to establish in-group and out-group membership, with standards of judgment based on clothes, manners, and physical appeal.…

  15. Universal design characteristic on themed streets

    Science.gov (United States)

    Harsritanto, Bangun IR; Indriastjario; Wijayanti

    2017-12-01

    People around the world can access the streets to fulfil their daily activities regardless of their gender, age, and abilities. The streetscape is an urban public space which is built to facilitate the basic needs of people as social being. The themed street is an urban streetscape designed and built in detail with a theme or special purpose in an of urban development process. Universal design facilitates the full range of human diversity as physical appearance, perception, cognitive abilities, sizes, and shapes. By designing for the diversity, the specialized streets become more functional and user-friendly. The purpose of this study is to examine several design characteristics of themed streets in several countries from three different continents using universal design principles for giving proper directions to develop more user-friendly streets. Literature review and case study were used as research methods. The literature review was extracted and compiled from manuscripts, streetscape design books, and from universal design principles. Furthermore, the constructed theory were used to examine the case studies of themed streets. The findings indicated that themed streets’ character design were strongly influenced by local cultural aspect even though the basic guidelines were universal design principles; the resumed design direction can be suggested universal along with the richness of local aspects.

  16. Model-Driven Theme/UML

    Science.gov (United States)

    Carton, Andrew; Driver, Cormac; Jackson, Andrew; Clarke, Siobhán

    Theme/UML is an existing approach to aspect-oriented modelling that supports the modularisation and composition of concerns, including crosscutting ones, in design. To date, its lack of integration with model-driven engineering (MDE) techniques has limited its benefits across the development lifecycle. Here, we describe our work on facilitating the use of Theme/UML as part of an MDE process. We have developed a transformation tool that adopts model-driven architecture (MDA) standards. It defines a concern composition mechanism, implemented as a model transformation, to support the enhanced modularisation features of Theme/UML. We evaluate our approach by applying it to the development of mobile, context-aware applications-an application area characterised by many non-functional requirements that manifest themselves as crosscutting concerns.

  17. The PAGES 2k Network, Phase 3: Themes and Call for Participation

    Science.gov (United States)

    von Gunten, L.; Mcgregor, H. V.; Martrat, B.; St George, S.; Neukom, R.; Bothe, O.; Linderholm, H. W.; Phipps, S. J.; Abram, N.

    2017-12-01

    The past 2000 years (the "2k" interval) provides critical context for understanding recent anthropogenic forcing of the climate and provides baseline information about the characteristics of natural climate variability. It also presents opportunities to improve the interpretation of proxy observations and to evaluate the climate models used to make future projections. Phases 1 and 2 of the PAGES 2k Network focussed on building regional and global surface temperature reconstructions for terrestrial regions and the oceans, and comparing these with model simulations to identify mechanisms of climate variation on interannual to bicentennial time scales. Phase 3 was launched in May 2017 and aims to address major questions around past hydroclimate, climate processes and proxy uncertainties. Its scientific themes are: Theme 1: "Climate Variability, Modes and Mechanisms"Further understand the mechanisms driving regional climate variability and change on interannual to centennial time scales; Theme 2: "Methods and Uncertainties"Reduce uncertainties in the interpretation of observations imprinted in paleoclimatic archives by environmental sensors; Theme 3: "Proxy and Model Understanding"Identify and analyse the extent of agreement between reconstructions and climate model simulations. Research is organized as a linked network of well-defined projects, identified and led by 2k community members. The 2k projects focus on specific scientific questions aligned with Phase 3 themes, rather than being defined along regional boundaries. New 2k projects can be proposed at any time at http://www.pastglobalchanges.org/ini/wg/2k-network/projects An enduring element of PAGES 2k is a culture of collegiality, transparency, and reciprocity. Phase 3 seeks to stimulate community based projects and facilitate collaboration between researchers from different regions and career stages, drawing on the breadth and depth of the global PAGES 2k community. All PAGES 2k projects also promote best

  18. Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia.

    Science.gov (United States)

    Ward, Joey; Strawbridge, Rona J; Bailey, Mark E S; Graham, Nicholas; Ferguson, Amy; Lyall, Donald M; Cullen, Breda; Pidgeon, Laura M; Cavanagh, Jonathan; Mackay, Daniel F; Pell, Jill P; O'Donovan, Michael; Escott-Price, Valentina; Smith, Daniel J

    2017-11-30

    Mood instability is a core clinical feature of affective and psychotic disorders. In keeping with the Research Domain Criteria approach, it may be a useful construct for identifying biology that cuts across psychiatric categories. We aimed to investigate the biological validity of a simple measure of mood instability and evaluate its genetic relationship with several psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD), schizophrenia, attention deficit hyperactivity disorder (ADHD), anxiety disorder and post-traumatic stress disorder (PTSD). We conducted a genome-wide association study (GWAS) of mood instability in 53,525 cases and 60,443 controls from UK Biobank, identifying four independently associated loci (on chromosomes 8, 9, 14 and 18), and a common single-nucleotide polymorphism (SNP)-based heritability estimate of ~8%. We found a strong genetic correlation between mood instability and MDD (r g  = 0.60, SE = 0.07, p = 8.95 × 10 -17 ) and a small but significant genetic correlation with both schizophrenia (r g  = 0.11, SE = 0.04, p = 0.01) and anxiety disorders (r g  = 0.28, SE = 0.14, p = 0.04), although no genetic correlation with BD, ADHD or PTSD was observed. Several genes at the associated loci may have a role in mood instability, including the DCC netrin 1 receptor (DCC) gene, eukaryotic translation initiation factor 2B subunit beta (eIF2B2), placental growth factor (PGF) and protein tyrosine phosphatase, receptor type D (PTPRD). Strengths of this study include the very large sample size, but our measure of mood instability may be limited by the use of a single question. Overall, this work suggests a polygenic basis for mood instability. This simple measure can be obtained in very large samples; our findings suggest that doing so may offer the opportunity to illuminate the fundamental biology of mood regulation.

  19. Light in Architecture as an Inspired Theme

    Science.gov (United States)

    Dębowska, Danuta

    2017-10-01

    The theme of the article is to highlight the important role of natural light in architecture. Natural light, or solar radiation absorbed by our sense of sight was a strong inspiration from ancient times. Originally constituted as a link between heaven and earth. It played a major role in shaping the places of worship, such as even Stonehenge. In the church architecture it was and still is the guiding element, the main matrix around builds an architecture narrative. Over the centuries, the study of the role of light in architecture, and in fact chiaroscuro, led to the culmination of solutions full of fantasy and “quirks” in the Baroque era (Baroque with Italian barocco: strange, exaggerated). Enamored of carved body and the use of multipurpose ornament topped was the discovery of a concave-convex façade parete ondulata created by Francesca Borrromini. Conscious manipulation of light developed, at the time, to a maximum of the art illusion and optical illusions in architectural buildings. Changing the perception of privilege in detail and introduce the principle of “beauty comes from functionality” in times of modernism meant that architects started to look for the most extreme simplicity. Sincerity of forms, and thus the lack of ornamentation, however, did not result in a lack of interest in light. On the contrary, the light became detail, eye-catching element against a smooth surface of the wall. The continuation of this concept of creating a strong password exposing Mies van der Rohe’s „less is more” took over the architecture created in the current minimalism. To minimize the detail with the introduction of large glazing resulted in strengthening the effect of opening the flow of light and penetrating the interior to the exterior. The principle of deep reflection on the light is certainly used in the design of monumental buildings, such as galleries, museums. It could be used more widely in the common architecture, noting the heritage and

  20. Themes of Suicide in the Kalevala.

    Science.gov (United States)

    Achte, Kalle; And Others

    1988-01-01

    The Kalevala, Finland's national epic, is a crucial element of Finnish cultural identity and important to Finnish culture. Violence, death, and suicide are often repeated themes in Finnish folklore. The Kalevala provides insight into past attitudes toward death. Traditions passed through generations have influenced people's attitudes toward…

  1. FY16 Strategic Themes White Paper.

    Energy Technology Data Exchange (ETDEWEB)

    Leland, Robert W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    The Science and Technology (S&T) Division 1000 Strategic Plan includes the Themes, Goals, and Actions for FY16. S&T will continue to support the Labs Strategic plan, Mission Areas and Program Management Units by focusing on four strategic themes that align with the targeted needs of the Labs. The themes presented in this plan are Mission Engagement, Bold Outcomes, Collaborative Environment, and the Safety Imperative. Collectively they emphasize diverse, collaborative teams and a self-reliant culture of safety that will deliver on our promise of exceptional service in the national interest like never before. Mission Engagement focuses on increasing collaboration at all levels but with emphasis at the strategic level with mission efforts across the labs. Bold Outcomes seeks to increase the ability to take thoughtful risks with the goal of achieving transformative breakthroughs more frequently. Collaborative environment strives for a self-aware, collaborative working environment that bridges the many cultures of Sandia. Finally, Safety Imperative aims to minimize the risk of serious injury and to continuously strengthen the safety culture. Each of these themes is accompanied by a brief vision statement, several goals, and planned actions to support those goals throughout FY16 and leading into FY17.

  2. Endangered Species & Biodiversity: A Classroom Project & Theme

    Science.gov (United States)

    Lauro, Brook

    2012-01-01

    Students discover the factors contributing to species losses worldwide by conducting a project about endangered species as a component of a larger classroom theme of biodiversity. Groups conduct research using online endangered- species databases and present results to the class using PowerPoint. Students will improve computer research abilities…

  3. Ten themes of viscous liquid dynamics

    DEFF Research Database (Denmark)

    Dyre, J. C.

    2007-01-01

    Ten ‘themes' of viscous liquid physics are discussed with a focus on how they point to a general description of equilibrium viscous liquid dynamics (i.e., fluctuations) at a given temperature. This description is based on standard time-dependent Ginzburg-Landau equations for the density fields...

  4. MLVA-16 typing of 295 marine mammal Brucella isolates from different animal and geographic origins identifies 7 major groups within Brucella ceti and Brucella pinnipedialis

    Directory of Open Access Journals (Sweden)

    Jacques Isabelle

    2009-07-01

    Full Text Available Abstract Background Since 1994, Brucella strains have been isolated from a wide range of marine mammals. They are currently recognized as two new Brucella species, B. pinnipedialis for the pinniped isolates and B. ceti for the cetacean isolates in agreement with host preference and specific phenotypic and molecular markers. In order to investigate the genetic relationships within the marine mammal Brucella isolates and with reference to terrestrial mammal Brucella isolates, we applied in this study the Multiple Loci VNTR (Variable Number of Tandem Repeats Analysis (MLVA approach. A previously published assay comprising 16 loci (MLVA-16 that has been shown to be highly relevant and efficient for typing and clustering Brucella strains from animal and human origin was used. Results 294 marine mammal Brucella strains collected in European waters from 173 animals and a human isolate from New Zealand presumably from marine origin were investigated by MLVA-16. Marine mammal Brucella isolates were shown to be different from the recognized terrestrial mammal Brucella species and biovars and corresponded to 3 major related groups, one specific of the B. ceti strains, one of the B. pinnipedialis strains and the last composed of the human isolate. In the B. ceti group, 3 subclusters were identified, distinguishing a cluster of dolphin, minke whale and porpoise isolates and two clusters mostly composed of dolphin isolates. These results were in accordance with published analyses using other phenotypic or molecular approaches, or different panels of VNTR loci. The B. pinnipedialis group could be similarly subdivided in 3 subclusters, one composed exclusively of isolates from hooded seals (Cystophora cristata and the two others comprising other seal species isolates. Conclusion The clustering analysis of a large collection of marine mammal Brucella isolates from European waters significantly strengthens the current view of the population structure of these two

  5. Hispanic Graduate Students' Mentoring Themes: Gender Roles in a Bicultural Context

    Science.gov (United States)

    Rudolph, Bonnie A.; Castillo, Carlos P.; Garcia, Vanessa G.; Martinez, Alina; Navarro, Fernando

    2015-01-01

    Male and female focus groups at a Hispanic Serving Institution (HSI) discussed mentoring of Hispanic graduate students. Using Thematic Analysis, investigators identified three main themes: Relationship Initiation and Development, Valued Relationship Qualities, and Context and Barriers. Relationship themes included mentor openness, trust,…

  6. Improvement of Theme Park Marketing Mode:A Case Study of Theme Parks in Chengdu

    Institute of Scientific and Technical Information of China (English)

    Min; LI; Gaoli; XIONG

    2013-01-01

    Construction of theme park has been launched since the early 1990s in Chengdu City,but ended up as a losing proposition after its short-term prosperity because of similar scale and similarity with those in other cities.As more international well-known theme parks entering the market,theme parks in Chengdu have been faced with the transition,and novel concepts are also introduced into the operation of these parks.To adapt to the market,it is imperative to make marketing strategies and combine marketing elements.Through analyzing current development of local theme parks and introducing successful marketing modes of domestic and overseas theme parks,a favorable marketing mode for theme parks in Chengdu was defined on the basis of fully exploring Ba-Shu culture(Ba and Shu are two ancient kingdoms in the history of Sichuan).By defining a favorable theme,focusing more on visitors’experience,devoting more in developing new products,adopting flexible price strategies,and integrating advertisement marketing,internet marketing,and other marketing methods,outstanding brands will be formed,and tourism cultures with distinguished features of Chengdu will be created.

  7. Meaning and Theme in Indian Style

    Directory of Open Access Journals (Sweden)

    Mojahed Gholami

    2016-12-01

    With a glimpse on what was said and a pause on the poems of Saeb Tabrizi, as one of the most seasoned poets in Indian style, it demonstrates part of his art and also illuminates the relation among word, meaning and theme in his poetry and viewpoint. He established multiple proportions among the concepts in his poem: sometimes he expressed a semantic unit as a content with diversities in word, or in some occasions, he expressed a semantic unit by different contents, with similar or dissimilar content maker elements, or even sometimes he use content maker elements for expressing multiple meanings and so on. Also it is necessary to be noted that when Saeb and the other poets of Indian style, measure the meaning by words, their meant is subjective matter and if the meaning comes with adjectives such as unfamiliar, narrow, distant, and so on, these words have used mainly in order to replace theme.

  8. Emerging themes in international business research

    OpenAIRE

    David A Griffith; Salih Tamer Cavusgil; Shichun Xu

    2008-01-01

    This study is motivated by two research questions: (1) Which recent contributions have been driving the research agenda in international business? (2) Which emerging themes in the literature are likely to set the stage for future work? To examine these questions, the study examined scholarly work in international business over the time period 1996–2006 in six leading international business journals (Journal of International Business Studies, Management International Review, Journal of World B...

  9. Objectives and Design of BLEEDS: A Cohort Study to Identify New Risk Factors and Predictors for Major Bleeding during Treatment with Vitamin K Antagonists.

    Science.gov (United States)

    van Rein, Nienke; Lijfering, Willem M; Bos, Mettine H A; Herruer, Martien H; Vermaas, Helga W; van der Meer, Felix J M; Reitsma, Pieter H

    2016-01-01

    Risk scores for patients who are at high risk for major bleeding complications during treatment with vitamin K antagonists (VKAs) do not perform that well. BLEEDS was initiated to search for new biomarkers that predict bleeding in these patients. To describe the outline and objectives of BLEEDS and to examine whether the study population is generalizable to other VKA treated populations. A cohort was created consisting of all patients starting VKA treatment at three Dutch anticoagulation clinics between January-2012 and July-2014. We stored leftover plasma and DNA following analysis of the INR. Of 16,706 eligible patients, 16,570 (99%) were included in BLEEDS and plasma was stored from 13,779 patients (83%). Patients had a mean age of 70 years (SD 14), 8713 were male (53%). The most common VKA indications were atrial fibrillation (10,876 patients, 66%) and venous thrombosis (3920 patients, 24%). 326 Major bleeds occurred during 17,613 years of follow-up (incidence rate 1.85/100 person years, 95%CI 1.66-2.06). The risk for major bleeding was highest in the initial three months of VKA treatment and increased when the international normalized ratio increased. These results and characteristics are in concordance with results from other VKA treated populations. BLEEDS is generalizable to other VKA treated populations and will permit innovative and unbiased research of biomarkers that may predict major bleeding during VKA treatment.

  10. Development and application of the Safe Performance Index as a risk-based methodology for identifying major hazard-related safety issues in underground coal mines

    Science.gov (United States)

    Kinilakodi, Harisha

    The underground coal mining industry has been under constant watch due to the high risk involved in its activities, and scrutiny increased because of the disasters that occurred in 2006-07. In the aftermath of the incidents, the U.S. Congress passed the Mine Improvement and New Emergency Response Act of 2006 (MINER Act), which strengthened the existing regulations and mandated new laws to address the various issues related to a safe working environment in the mines. Risk analysis in any form should be done on a regular basis to tackle the possibility of unwanted major hazard-related events such as explosions, outbursts, airbursts, inundations, spontaneous combustion, and roof fall instabilities. One of the responses by the Mine Safety and Health Administration (MSHA) in 2007 involved a new pattern of violations (POV) process to target mines with a poor safety performance, specifically to improve their safety. However, the 2010 disaster (worst in 40 years) gave an impression that the collective effort of the industry, federal/state agencies, and researchers to achieve the goal of zero fatalities and serious injuries has gone awry. The Safe Performance Index (SPI) methodology developed in this research is a straight-forward, effective, transparent, and reproducible approach that can help in identifying and addressing some of the existing issues while targeting (poor safety performance) mines which need help. It combines three injury and three citation measures that are scaled to have an equal mean (5.0) in a balanced way with proportionate weighting factors (0.05, 0.15, 0.30) and overall normalizing factor (15) into a mine safety performance evaluation tool. It can be used to assess the relative safety-related risk of mines, including by mine-size category. Using 2008 and 2009 data, comparisons were made of SPI-associated, normalized safety performance measures across mine-size categories, with emphasis on small-mine safety performance as compared to large- and

  11. Themes in human work interaction design

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Mark Pejtersen, Annelise; Clemmensen, Torkil

    2008-01-01

    Design (name HWID) through the last two and half years since the commencement of this Working Group. The paper thus provides an introduction to the theory and empirical evidence that lie behind the combination of empirical work studies and interaction design. It also recommends key topics for future......Abstract. This paper raises themes that are seen as some of the challenges facing the emerging practice and research field of Human Work Interaction Design. The paper has its offset in the discussions and writings that have been dominant within the IFIP Working Group on Human Work Interaction...

  12. The Underlying Theme of Shakespeare's Tragedy Tempest

    Institute of Scientific and Technical Information of China (English)

    谢倩

    2014-01-01

    The Tempest is one of William Shakespeare's famous play, which mainly focused on the magic and the Postcolonial oppression. The work exposed the crucial harm and inhumanity in those years. In order to demonstrate the deep meaning of this great work and everlasting influence it has made, this essay picks out two parts of its significant themes and gives them a detailed explanation. By demonstrate those profound meanings,the real value of The Tempest may be clearer and the readers can have a better understanding of it.

  13. Sex differences in the prediction of the effectiveness of paroxetine for patients with major depressive disorder identified using a receiver operating characteristic curve analysis for early response.

    Science.gov (United States)

    Tomita, Tetsu; Yasui-Furukori, Norio; Norio, Yasui-Furukori; Sato, Yasushi; Nakagami, Taku; Tsuchimine, Shoko; Kaneda, Ayako; Kaneko, Sunao

    2014-01-01

    We investigated cutoff values for the early response of patients with major depressive disorder to paroxetine and their sex differences by using a receiver operating characteristic (ROC) curve analysis to predict the effectiveness of paroxetine. In total, 120 patients with major depressive disorder were enrolled and treated with 10-40 mg/day paroxetine for 6 weeks; 89 patients completed the protocol. A clinical evaluation using the Montgomery-Asberg Depression Rating Scale (MADRS) was performed at weeks 0, 1, 2, 4, and 6. In male subjects, the cutoff values for MADRS improvement rating in week 1, week 2, and week 4 were 20.9%, 34.9%, and 33.3%, respectively. The sensitivities and the specificities were 83.3% and 80.0%, 83.3% and 80.0%, and 100% and 90%, respectively. The areas under the curve (AUC) were 0.908, 0.821, and 0.979, respectively. In female subjects, the cutoff values for the MADRS improvement rating in week 1, week 2, and week 4 were 21.4%, 35.7%, and 32.3%, respectively. The sensitivities and the specificities were 71.4% and 84.6%, 73.8% and 76.9%, and 90.5% and 76.9%, respectively. The AUCs were 0.781, 0.735, and 0.904, respectively. Early improvement with paroxetine may predict the long-term response. The accuracy of the prediction for the response is higher in male subjects.

  14. Genome-Wide Linkage and Association Analysis Identifies Major Gene Loci for Guttural Pouch Tympany in Arabian and German Warmblood Horses

    Science.gov (United States)

    Metzger, Julia; Ohnesorge, Bernhard; Distl, Ottmar

    2012-01-01

    Equine guttural pouch tympany (GPT) is a hereditary condition affecting foals in their first months of life. Complex segregation analyses in Arabian and German warmblood horses showed the involvement of a major gene as very likely. Genome-wide linkage and association analyses including a high density marker set of single nucleotide polymorphisms (SNPs) were performed to map the genomic region harbouring the potential major gene for GPT. A total of 85 Arabian and 373 German warmblood horses were genotyped on the Illumina equine SNP50 beadchip. Non-parametric multipoint linkage analyses showed genome-wide significance on horse chromosomes (ECA) 3 for German warmblood at 16–26 Mb and 34–55 Mb and for Arabian on ECA15 at 64–65 Mb. Genome-wide association analyses confirmed the linked regions for both breeds. In Arabian, genome-wide association was detected at 64 Mb within the region with the highest linkage peak on ECA15. For German warmblood, signals for genome-wide association were close to the peak region of linkage at 52 Mb on ECA3. The odds ratio for the SNP with the highest genome-wide association was 0.12 for the Arabian. In conclusion, the refinement of the regions with the Illumina equine SNP50 beadchip is an important step to unravel the responsible mutations for GPT. PMID:22848553

  15. Higher 5-HT1A autoreceptor binding as an endophenotype for major depressive disorder identified in high risk offspring - A pilot study.

    Science.gov (United States)

    Milak, Matthew S; Pantazatos, Spiro; Rashid, Rain; Zanderigo, Francesca; DeLorenzo, Christine; Hesselgrave, Natalie; Ogden, R Todd; Oquendo, Maria A; Mulhern, Stephanie T; Miller, Jeffrey M; Burke, Ainsley K; Parsey, Ramin V; Mann, J John

    2018-04-13

    Higher serotonin-1A (5-HT 1A ) receptor binding potential (BP F ) has been found in major depressive disorder (MDD) during and between major depressive episodes. We investigated whether higher 5-HT 1A binding is a biologic trait transmitted to healthy high risk (HR) offspring of MDD probands. Data were collected contemporaneously from: nine HR, 30 depressed not-recently medicated (NRM) MDD, 18 remitted NRM MDD, 51 healthy volunteer (HV) subjects. Subjects underwent positron emission tomography (PET) using [ 11 C]WAY100635 to quantify 5-HT 1A BP F , estimated using metabolite, free fraction-corrected arterial input function and cerebellar white matter as reference region. Multivoxel pattern analyses (MVPA) of PET data evaluated group status classification of individuals. When tested across 13 regions of interest, an effect of diagnosis is found on BP F which remains significant after correction for sex, age, injected mass and dose: HR have higher BP F than HV (84.3% higher in midbrain raphe, 40.8% higher in hippocampus, mean BP F across all 13 brain regions is 49.9% ± 11.8% higher). Voxel-level BP F maps distinguish HR vs. HV. Elevated 5-HT 1A BP F appears to be a familially transmitted trait abnormality. Future studies are needed to replicate this finding in a larger cohort and demonstrate the link to the familial transmission of mood disorders. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Converging cellular themes for the hereditary spastic paraplegias.

    Science.gov (United States)

    Blackstone, Craig

    2018-05-10

    Hereditary spastic paraplegias (HSPs) are neurologic disorders characterized by prominent lower-extremity spasticity, resulting from a length-dependent axonopathy of corticospinal upper motor neurons. They are among the most genetically-diverse neurologic disorders, with >80 distinct genetic loci and over 60 identified genes. Studies investigating the molecular pathogenesis underlying HSPs have emphasized the importance of converging cellular pathogenic themes in the most common forms of HSP, providing compelling targets for therapy. Most notably, these include organelle shaping and biogenesis as well as membrane and cargo trafficking. Published by Elsevier Ltd.

  17. Identifying the major bacteria causing intramammary infections in individual milk samples of sheep and goats using traditional bacteria culturing and real-time polymerase chain reaction.

    Science.gov (United States)

    Rovai, M; Caja, G; Salama, A A K; Jubert, A; Lázaro, B; Lázaro, M; Leitner, G

    2014-09-01

    Use of DNA-based methods, such as real-time PCR, has increased the sensitivity and shortened the time for bacterial identification, compared with traditional bacteriology; however, results should be interpreted carefully because a positive PCR result does not necessarily mean that an infection exists. One hundred eight lactating dairy ewes (56 Manchega and 52 Lacaune) and 24 Murciano-Granadina dairy goats were used for identifying the main bacteria causing intramammary infections (IMI) using traditional bacterial culturing and real-time PCR and their effects on milk performance. Udder-half milk samples were taken for bacterial culturing and somatic cell count (SCC) 3 times throughout lactation. Intramammary infections were assessed based on bacteria isolated in ≥2 samplings accompanied by increased SCC. Prevalence of subclinical IMI was 42.9% in Manchega and 50.0% in Lacaune ewes and 41.7% in goats, with the estimated milk yield loss being 13.1, 17.9, and 18.0%, respectively. According to bacteriology results, 87% of the identified single bacteria species (with more than 3 colonies/plate) or culture-negative growth were identical throughout samplings, which agreed 98.9% with the PCR results. Nevertheless, the study emphasized that 1 sampling may not be sufficient to determine IMI and, therefore, other inflammatory responses such as increased SCC should be monitored to identify true infections. Moreover, when PCR methodology is used, aseptic and precise milk sampling procedures are key for avoiding false-positive amplifications. In conclusion, both PCR and bacterial culture methods proved to have similar accuracy for identifying infective bacteria in sheep and goats. The final choice will depend on their response time and cost analysis, according to the requirements and farm management strategy. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  18. Types of centredness in health care: themes and concepts.

    Science.gov (United States)

    Hughes, Julian C; Bamford, Claire; May, Carl

    2008-12-01

    For a variety of sociological reasons, different types of centredness have become important in health and social care. In trying to characterize one type of centredness, we were led to consider, at a conceptual level, the importance of the notion of centredness in general and the reasons for there being different types of centeredness. We searched the literature for papers on client-, family-, patient-, person- and relationship- centred care. We identified reviews or papers that defined or discussed the notions at a conceptual level. The reviews and papers were analyzed as text transcripts. We identified 10 themes that were common to all the types of centredness. At a conceptual level we could not identify thematic differences between the types of centredness. These findings were subjected to a philosophical critique using ideas derived from Wittgenstein. Different types of centredness are required in different contexts. The differences are justified by their practical utility. The unifying themes of centredness, however, reflect a movement in favour of increasing the social, psychological, cultural and ethical sensitivity of our human encounters.

  19. What is shared, what is different? Core relational themes and expressive displays of eight positive emotions.

    Science.gov (United States)

    Campos, Belinda; Shiota, Michelle N; Keltner, Dacher; Gonzaga, Gian C; Goetz, Jennifer L

    2013-01-01

    Understanding positive emotions' shared and differentiating features can yield valuable insight into the structure of positive emotion space and identify emotion states, or aspects of emotion states, that are most relevant for particular psychological processes and outcomes. We report two studies that examined core relational themes (Study 1) and expressive displays (Study 2) for eight positive emotion constructs--amusement, awe, contentment, gratitude, interest, joy, love, and pride. Across studies, all eight emotions shared one quality: high positive valence. Distinctive core relational theme and expressive display patterns were found for four emotions--amusement, awe, interest, and pride. Gratitude was associated with a distinct core relational theme but not an expressive display. Joy and love were each associated with a distinct expressive display but their core relational themes also characterised pride and gratitude, respectively. Contentment was associated with a distinct expressive display but not a core relational theme. The implications of this work for the study of positive emotion are discussed.

  20. An abbreviated MLVA identifies Escherichia coli ST131 as the major extended-spectrum β-lactamase-producing lineage in the Copenhagen area

    DEFF Research Database (Denmark)

    Nielsen, J B; Albayati, A; Jørgensen, Rikke Lind

    2013-01-01

    with multilocus sequence typing (MLST) for typing cefpodoxime-resistant Escherichia coli (E. coli). Further, we identified the causative resistance mechanisms and epidemiological type of infection for isolates producing extended-spectrum β-lactamases (ESBLs). A collection of E. coli resistant to cefpodoxime...... community-onset infections (COI), regardless of the ST. Patients with COI were significantly more often of female gender and younger age compared to healthcare-associated infections (HCAI) and hospital-onset infections (HOI). In conclusion, the modified MLVA is a useful tool for the rapid typing of E. coli...

  1. Using the Sustainability Monitoring and Assessment Routine (SMART for the Systematic Analysis of Trade-Offs and Synergies between Sustainability Dimensions and Themes at Farm Level

    Directory of Open Access Journals (Sweden)

    Christian Schader

    2016-03-01

    Full Text Available When trying to optimize the sustainability performance of farms and farming systems, a consideration of trade-offs and synergies between different themes and dimensions is required. The aim of this paper is to perform a systematic analysis of trade-offs and synergies across all dimensions and themes. To achieve this aim we used the Sustainability Monitoring and Assessment Routine (SMART-Farm Tool which operationalizes the Sustainability Assessment of Food and Agriculture Systems (SAFA Guidelines by defining science-based indicator sets and assessment procedures. It identifies the degree of goal achievement with respect to the 58 themes defined in the SAFA Guidelines using an impact matrix that defines 327 indicators and 1769 relations between sustainability themes and indicators. We illustrate how the SMART-Farm Tool can be successfully applied to assess the sustainability performance of farms of different types and in different geographic regions. Our analysis revealed important synergies between themes within a sustainability dimension and across dimensions. We found major trade-offs within the environmental dimension and between the environmental and economic dimension. The trade-offs within the environmental dimension were even larger than the trade-offs with other dimensions. The study also underlines the importance of the governance dimension with regard to achieving a good level of performance in the other dimensions.

  2. Integrated network analysis identifies fight-club nodes as a class of hubs encompassing key putative switch genes that induce major transcriptome reprogramming during grapevine development.

    Science.gov (United States)

    Palumbo, Maria Concetta; Zenoni, Sara; Fasoli, Marianna; Massonnet, Mélanie; Farina, Lorenzo; Castiglione, Filippo; Pezzotti, Mario; Paci, Paola

    2014-12-01

    We developed an approach that integrates different network-based methods to analyze the correlation network arising from large-scale gene expression data. By studying grapevine (Vitis vinifera) and tomato (Solanum lycopersicum) gene expression atlases and a grapevine berry transcriptomic data set during the transition from immature to mature growth, we identified a category named "fight-club hubs" characterized by a marked negative correlation with the expression profiles of neighboring genes in the network. A special subset named "switch genes" was identified, with the additional property of many significant negative correlations outside their own group in the network. Switch genes are involved in multiple processes and include transcription factors that may be considered master regulators of the previously reported transcriptome remodeling that marks the developmental shift from immature to mature growth. All switch genes, expressed at low levels in vegetative/green tissues, showed a significant increase in mature/woody organs, suggesting a potential regulatory role during the developmental transition. Finally, our analysis of tomato gene expression data sets showed that wild-type switch genes are downregulated in ripening-deficient mutants. The identification of known master regulators of tomato fruit maturation suggests our method is suitable for the detection of key regulators of organ development in different fleshy fruit crops. © 2014 American Society of Plant Biologists. All rights reserved.

  3. Identifying latent profiles of posttraumatic stress and major depression symptoms in Canadian veterans: Exploring differences across profiles in health related functioning.

    Science.gov (United States)

    Armour, Cherie; Contractor, Ateka; Elhai, Jon D; Stringer, Maurice; Lyle, Gary; Forbes, David; Richardson, J Don

    2015-07-30

    Posttraumatic stress disorder (PTSD) has been consistently reported as being highly comorbid with major depressive disorder (MDD) and as being associated with health related functional impairment (HRF). We used archival data from 283 previously war-zone deployed Canadian veterans. Latent profile analysis (LPA) was used to uncover patterns of PTSD and MDD comorbidity as measured via the PTSD Checklist-Military version (PCL-M) and the Patient Health Questionnaire-9 (PHQ-9). Individual membership of latent classes was used in a series of one-way ANOVAs to ascertain group differences related to HRF as measured via the Short-Form-36 Health Survey (SF-36). LPA resulted in three discrete patterns of PTSD and MDD comorbidity which were characterized by high symptoms of PTSD and MDD, moderate symptoms, and low symptoms. All ANOVAs comparing class membership on the SF-36 subscales were statistically significant demonstrating group differences across levels of HRF. The group with the highest symptoms reported the worst HRF followed by the medium and low symptom groups. These findings are clinically relevant as they demonstrate the need for continual assessment and targeted treatment of co-occurring PTSD and MDD. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  4. Symptoms of major depressive disorder subsequent to child maltreatment: Examining change across multiple levels of analysis to identify transdiagnostic risk pathways.

    Science.gov (United States)

    Shenk, Chad E; Griffin, Amanda M; O'Donnell, Kieran J

    2015-11-01

    Major depressive disorder (MDD) is a prevalent psychiatric condition in the child maltreatment population. However, not all children who have been maltreated will develop MDD or MDD symptoms, suggesting the presence of unique risk pathways that explain how certain children develop MDD symptoms when others do not. The current study tested several candidate risk pathways to MDD symptoms following child maltreatment: neuroendocrine, autonomic, affective, and emotion regulation. Female adolescents (N = 110; age range = 14-19) were recruited into a substantiated child maltreatment or comparison condition and completed a laboratory stressor, saliva samples, and measures of emotion regulation, negative affect, and MDD symptoms. MDD symptoms were reassessed 18 months later. Mediational modeling revealed that emotion regulation was the only significant indirect effect of the relationship between child maltreatment and subsequent MDD symptoms, demonstrating that children exposed to maltreatment had greater difficulties managing affective states that in turn led to more severe MDD symptoms. These results highlight the importance of emotion dysregulation as a central risk pathway to MDD following child maltreatment. Areas of future research and implications for optimizing prevention and clinical intervention through the direct targeting of transdiagnostic risk pathways are discussed.

  5. Symptoms of Major Depressive Disorder Subsequent to Child Maltreatment: Examining Change across Multiple Levels of Analysis to Identify Transdiagnostic Risk Pathways

    Science.gov (United States)

    Shenk, Chad E.; Griffin, Amanda M.; O’Donnell, Kieran J.

    2016-01-01

    Major depressive disorder (MDD) is a prevalent psychiatric condition in the child maltreatment population. However, not all children who have been maltreated will develop MDD or MDD symptoms, suggesting the presence of unique risk pathways that explain how certain children develop MDD symptoms when others do not. The current study tested several candidate risk pathways to MDD symptoms following child maltreatment: 1) neuroendocrine, 2) autonomic, 3) affective, and 4) emotion regulation. Female adolescents (N=110; Age range: 14–19) were recruited into a substantiated child maltreatment or comparison condition and completed a laboratory stressor, saliva samples, and measures of emotion regulation, negative affect, and MDD symptoms. MDD symptoms were reassessed eighteen months later. Mediational modeling revealed that emotion regulation was the only significant indirect effect of the relationship between child maltreatment and subsequent MDD symptoms, demonstrating that children exposed to maltreatment had greater difficulties managing affective states that in turn led to more severe MDD symptoms. These results highlight the importance of emotion dysregulation as a central risk pathway to MDD following child maltreatment. Areas of future research and implications for optimizing prevention and clinical intervention through the direct targeting of transdiagnostic risk pathways are discussed. PMID:26535940

  6. Creation of meanings on the theme

    Directory of Open Access Journals (Sweden)

    Eveline Borges

    2011-12-01

    Full Text Available Investments in policies for science teachers, as well as their adaptation to new realities and technologies are essential, since the teacher is the key to changing mindsets and attitudes of their students. Thus, conceptual discussions are proposed between chemistry teachers in a virtual environment on the Moodle platform on topics previously chosen by the education teacher. The objective is to analyze the process of creating meanings of participants of the forum on the theme "nature of science." It was noticed that new media can help building students' knowledge and motivate them to expand their research and scientific readings; however, rules must be preestablished so that a real interaction and mediation could occur. Initiatives like these are useful for the understanding of scientific and technical fields, and may also facilitate communication and interaction between teachers and students.

  7. Rotating swings—a theme with variations

    Science.gov (United States)

    Pendrill, Ann-Marie

    2016-01-01

    Rotating swing rides can be found in many amusement parks, in many different versions. The ‘wave swinger’ ride, which introduces a wave motion by tilting the roof, is among the classical amusement rides that are found in many different parks, in different sizes, from a number of different makes and names, and varying thematization. The ‘StarFlyer’ is a more recent version, adding the thrill of lifting the riders 60 m or more over the ground. These rotating swing rides involve beautiful physics, often surprising, but easily observed, when brought to attention. The rides can be used for student worksheet tasks and assignments of different degrees of difficulty, across many math and physics topics. This paper presents a number of variations of student tasks relating to the theme of rotating swing rides.

  8. I. L. Caragiale. Theme and Variations

    Directory of Open Access Journals (Sweden)

    Adela Drăucean

    2010-11-01

    Full Text Available Analyzing Caragiale’s work, a so called “unity in variety” can be noticed and his entire creation may be named after one of his sketches, Plot and variations. Since the fire on Dealul Spirii, a real story, had been given five different interpretations by the local media, so must we understand Caragiale’s literary pieces: they have a “plot”, i.e. the society, and several “variants” (forms, i.e. the events or happenings of all kinds. As an urban writer, Caragiale was preoccupied with the town and its very life, but also with folk themes and motifs. He also described the countryside with its scenery, inns and innkeepers, the places where people used to meet and talk. Trades and their professions were presented in his sketches and stories, too

  9. The Internet Marketing of Disney Theme Parks

    Directory of Open Access Journals (Sweden)

    Carol J. Auster

    2013-03-01

    Full Text Available The purpose of this study was to analyze the portrayal of gender and race in the images on the official Disney websites used to market five theme parks: the Disneyland Parks in California, Paris, Tokyo, and Hong Kong, and the Magic Kingdom in Florida. This is important because of the growth of e-commerce, Disney’s global influence, and the potential impact on those who view the images. The 452 images that had Disney human characters, human-like characters, animals, cast members, or guests were coded for gender. The main gender hypothesis, that the percentage of male-dominated images would exceed the percentage of female-dominated images, was tested using gender disparity values, which measured the gap between the percentage of male-dominated and female-dominated images. The hypothesis tended to be supported overall, and for most of the resorts (e.g., Florida, lands (e.g., Adventureland, and activities (attractions, entertainment, dining for human characters, human-like characters, animals, and cast members, but not for guests. Furthermore, the hypotheses that gender disparity values would be highest for images of animals and lowest for images of guests was supported for all five resorts, six of eight lands, and all three activities. Additional analysis also revealed the preponderance of same-sex pairings in parent–child combinations in the images. With regard to race, while the images of some theme parks displayed more racial diversity among their guests than others, in some images, individuals of different races were shown interacting whereas in others they were not. Explanations for these findings and suggestions for future research are discussed.

  10. Exome sequencing identifies DYNC2H1 mutations as a common cause of asphyxiating thoracic dystrophy (Jeune syndrome) without major polydactyly, renal or retinal involvement

    Science.gov (United States)

    Schmidts, Miriam; Arts, Heleen H; Bongers, Ernie M H F; Yap, Zhimin; Oud, Machteld M; Antony, Dinu; Duijkers, Lonneke; Emes, Richard D; Stalker, Jim; Yntema, Jan-Bart L; Plagnol, Vincent; Hoischen, Alexander; Gilissen, Christian; Forsythe, Elisabeth; Lausch, Ekkehart; Veltman, Joris A; Roeleveld, Nel; Superti-Furga, Andrea; Kutkowska-Kazmierczak, Anna; Kamsteeg, Erik-Jan; Elçioğlu, Nursel; van Maarle, Merel C; Graul-Neumann, Luitgard M; Devriendt, Koenraad; Smithson, Sarah F; Wellesley, Diana; Verbeek, Nienke E; Hennekam, Raoul C M; Kayserili, Hulya; Scambler, Peter J; Beales, Philip L; Knoers, Nine VAM; Roepman, Ronald; Mitchison, Hannah M

    2013-01-01

    Background Jeune asphyxiating thoracic dystrophy (JATD) is a rare, often lethal, recessively inherited chondrodysplasia characterised by shortened ribs and long bones, sometimes accompanied by polydactyly, and renal, liver and retinal disease. Mutations in intraflagellar transport (IFT) genes cause JATD, including the IFT dynein-2 motor subunit gene DYNC2H1. Genetic heterogeneity and the large DYNC2H1 gene size have hindered JATD genetic diagnosis. Aims and methods To determine the contribution to JATD we screened DYNC2H1 in 71 JATD patients JATD patients combining SNP mapping, Sanger sequencing and exome sequencing. Results and conclusions We detected 34 DYNC2H1 mutations in 29/71 (41%) patients from 19/57 families (33%), showing it as a major cause of JATD especially in Northern European patients. This included 13 early protein termination mutations (nonsense/frameshift, deletion, splice site) but no patients carried these in combination, suggesting the human phenotype is at least partly hypomorphic. In addition, 21 missense mutations were distributed across DYNC2H1 and these showed some clustering to functional domains, especially the ATP motor domain. DYNC2H1 patients largely lacked significant extra-skeletal involvement, demonstrating an important genotype–phenotype correlation in JATD. Significant variability exists in the course and severity of the thoracic phenotype, both between affected siblings with identical DYNC2H1 alleles and among individuals with different alleles, which suggests the DYNC2H1 phenotype might be subject to modifier alleles, non-genetic or epigenetic factors. Assessment of fibroblasts from patients showed accumulation of anterograde IFT proteins in the ciliary tips, confirming defects similar to patients with other retrograde IFT machinery mutations, which may be of undervalued potential for diagnostic purposes. PMID:23456818

  11. Mapping the Landscape of Future Research Themes in Supply Chain Management

    DEFF Research Database (Denmark)

    Wieland, Andreas; Handfield, Robert; Durach, Christian F.

    2016-01-01

    Supply chain researchers are confronted with a dizzying array of research questions, many of which are not mutually independent. This research was motivated by the need to map the landscape of research themes, identify potential overlapping areas and interactions, and provide guidelines on areas...... of focus for researchers to pursue. We conducted a three-phase research study, beginning with an open-ended collection of opinions on research themes collected from 102 supply chain management (SCM) researchers, followed by an evaluation of a consolidated list of themes by 141 SCM researchers...

  12. Enhancing Students’ Local Knowledge Through Themed Garden Project

    Directory of Open Access Journals (Sweden)

    Esa Norizan

    2015-01-01

    Full Text Available Traditional or local knowledge is a major issue to be focused on, particularly since the implementation of the Strategic Plan for Biodiversity 2011–2020 and the Aichi Targets “Living in Harmony with Nature”. According to the strategic goals, by 2020, conservation of biodiversity and its sustainable use incorporate what local and indigenous communities have within their traditional knowledge, innovation and practice and their customary use of biological resources are respected at all relevant levels. The older generation among the local people usually use medicinal herbs for various ailments, health care and other cultural purposes. However, encroaching industrialization and the changes in today’s life styles are responsible for the decreasing practice in the local use of herbs especially for healing purposes. It is, therefore, felt worthwhile to encourage young generations such as school children to gain knowledge about these local herbs and record the native uses of these herbs before the information is lost. One biodiversity education program was conducted to facilitate secondary school students to set up a themed garden and find out the local knowledge of the plants they grew in their garden from their family members or communities. The findings revealed that students’ local knowledge on healing improved after they joined the program. Therefore, it is proposed that the themed garden project can enhance students’ local knowledge.

  13. On Themes of the Eagle by Alfred Tennyson

    Institute of Scientific and Technical Information of China (English)

    陈晓庆

    2009-01-01

    Theme is significant to poetry.Not only music but also theme is related to poetry since its birth.Usually great poems have more than one theme.Nowadays different approaches of literary analysis are on stage.The different approaches are employed to expound the rich themes of The Eagle-in memorial of Hallam,in praise of Britain's colonial expansion and in eulogy of nature.

  14. Taoism themes in modern chinese cinematography

    OpenAIRE

    Andreev, D. I.; Андреев, Д. И.

    2014-01-01

    The paper demonstrates some peculiarities of Taoism, a Chinese national religion, in its intersection with Chinese cinematography. The paper analyses how Taoism themes influence modern Chinese films and how they are interpreted in plots, characters and symbolism of these films. В работе рассматриваются некоторые особенности Даосизма, национальной религии Китая, в его корреляции с китайским кинематографом. В работе анализируется, каким образом Даосские мотивы влияют на современный китайский...

  15. THE THEME OF THE CRUCIFIXION OF CHRIST IN VISUAL ARTS

    Directory of Open Access Journals (Sweden)

    Adrian STOLERIU

    2015-06-01

    Full Text Available The Crucifixion of Christ is one of the major Biblical events in the context of the four Gospels, also marking one of the most frequently met themes in the iconography of Christian art. The focus of the paper is to underline the main aspects of the visual representation of this tense moment in the history of Christianity, referring to representative works of the artistic heritage inspired by the event of Christ’s death on the cross. Thus, a number of famous works of art history are analyzed in relation to the described composition, the represented characters and their importance. They belong both to traditional artistic fields, such as painting, to modern ones, thus taking into account some of the most popular film representations on this topic.

  16. Effects of Instructions on Theme Grading: Grammatical vs. Holistic

    Science.gov (United States)

    Follman, John; And Others

    1971-01-01

    Twelve college seniors in an English methods course were assigned to three treatment groups, Grammatical, Holistic, and Both. Each group received different instructions but graded the same 10 themes. Themes graded for grammatical errors received lower grades than the same themes graded holistically. (NH)

  17. Theme 10: greenhouse effect transport policies and urban organization

    International Nuclear Information System (INIS)

    2002-07-01

    This document describes the reference framework of the theme 10 ''greenhouse effect, transport policies and urban organization'' which is a part of the urban transports interface. It presents the specific actions realized by the theme 10 for a future integration in theme 1, 5 and 8. (A.L.B.)

  18. The themes, institutions, and people of medical education research 1988-2010: content analysis of abstracts from six journals.

    Science.gov (United States)

    Rotgans, Jerome I

    2012-10-01

    The present study aimed at providing an overview of the most common themes of research into medical education. Changes in frequency of occurrence of these themes over time and differences between US and European journals were studied. The most productive institutions and researchers in the field were examined. A content analysis was carried out on 10,168 abstracts extracted from the six most influential journals in medical education published since 1988. Twenty-nine major themes were identified, of which student assessment, clinical and communication skills, clinical clerkships, and problem-based learning were the most prominent ones. Some of these themes, such as multiple-choice examinations or computer-assisted instruction seemed to have had their day, whereas other topics, such as the study of clinical clerkships, clinical reasoning, and scholarship in education were on their way up. Medical education research turned out to be a thoroughly international affair to which both US and European research centers contribute. The medical education literature shows an overwhelming emphasis on the preparation of medical students for professional practice. Moreover, the emphasis is very much on the individual student; most research seems to have been conducted with a psychological perspective in mind. It is argued that medical education research would profit from broadening its scope, including sociological, economical, ecological, and system perspectives. These perspectives might bring answers to new questions relevant to the quality of medical education. It is suggested that medical education is in need of moving beyond the conventional effectiveness-driven research approach to a more theory- and discovery-driven approach.

  19. Theme 10: greenhouse effect transport policies and urban organization; Theme 10: effet de serre politiques de deplacements et organisation urbaine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This document describes the reference framework of the theme 10 ''greenhouse effect, transport policies and urban organization'' which is a part of the urban transports interface. It presents the specific actions realized by the theme 10 for a future integration in theme 1, 5 and 8. (A.L.B.)

  20. METHODOLOGY FOR CROSS-CURRICULAR THEME OF THE ENVIRONMENTAL AXIS

    Directory of Open Access Journals (Sweden)

    José Luis Aparicio López

    2015-04-01

    Full Text Available This article introduces a methodology to identify the presence of the environmental axis in educational programs in Bachelors in the Universidad Autónoma de Guerrero, Mexico. It is sustained on competency-based education and constructionism, due to they appeal to humanism to deal current problems. It is composed of four phases: committee conformation, theoretical and conceptual concerning analysis, construction and application of instruments on a PE, and identification of the cross-curricular theme level. Even though the proposed methodology is applied to the environment, it is feasible to adapt to other axes, such as human rights, multiculturalism, and poverty, relevant to the educational context of the state of Guerrero.

  1. A New Twist on an Old Theme.

    Science.gov (United States)

    Marchetti, Honey

    A work-study student assistant was employed at the Carnegie Mellon University Engineering and Science Library to help prepare documentation for a new library program. The student, a junior professional writing major, used the Apple Macintosh microcomputer to design a brochure, billing worksheet, and spreadsheet for the new program. On completion…

  2. Using Philosophical Liberalism and Philosophical Conservatism as an Organizing Theme in the First Half of the American History Survey

    Science.gov (United States)

    Morris, Richard J.

    2009-01-01

    Since approximately 1970, many historians have been seeking a unifying theme for the American History Survey. Early in the twentieth century, Progressive historians identified class conflict as the main theme in American History, but during the 1950s and 1960s, this view was challenged by the Consensus Schools' assertion that Americans have always…

  3. Foster Youth Who Have Succeeded in Higher Education: Common Themes. Information Brief. Volume 7, Issue 1

    Science.gov (United States)

    Lovitt, Thomas; Emerson, John

    2008-01-01

    The publication is based on interviews conducted by Casey Family Programs with eight foster youth who graduated from college to learn their perspectives on going to college and obtaining a degree despite numerous barriers. This report presents fifteen major themes concerning college success and their general outlook on life. Their accomplishments…

  4. Discourse Analysis and the teaching of Biochemistry: contextualized learning based on "alcoholic beverages" as generative theme

    Directory of Open Access Journals (Sweden)

    R. M.; A. S. Lima; Conceição

    2017-07-01

    Full Text Available The World Health Organization classifies alcohol as a psychoactive substance capable of producing addiction, associated to various diseases and social problems. However, it is largely consumed in the various social strata by youngster which ultimately leads to its common practice. These individuals know little about the harms posed by excessive consumption of alcoholic beverages. In this scenario, education is a major promoter of change in this longstanding social behavior. This study aimed at promoting the consolidation of the teaching of Biology by using alcohol as generative themes for the development of contents in Biochemistry, as well as elaborating a methodology that will stimulate learning about ethanol metabolism. A research was carried out with 316 individuals in the age group 13-19, enrolled in four public High Schools in the Municipality of Campos dos Goytacazes/RJ. Prevalence of alcoholic beverages was identified among 72%, and beginning of such habit was found in the 13-15 age group motivated by curiosity or peer influence. Considering these data, an educational methodology was developed based on the concept of generative themes by Paulo Freire and structured by Delizoicov (2007. To verify the value of such methodology in Biochemistry classroom, data was collected by applying a questionnaire and images with texts produced by students. Several didactic resources designed by the authors were used, such as slide presentation and a roulette game named “Bioquimicados”. Critical analysis of texts written by students were carried out before and after the class using DTA. Students developed more grounded scientific concepts, making use of terms common in scientific language. This suggests that the use of the Generating Issue in a lesson based on problematization, and supported by a ludic activity, provided a meaningful contribution to improve the students' understanding of the scientific content. A non-traditional class promotes

  5. Themes of nanoscience for the introductory physics course

    International Nuclear Information System (INIS)

    Planinsic, Gorazd; Lindell, Anssi; Remskar, Maja

    2009-01-01

    We present three experimental themes and one discussion theme that proved to be suitable for introducing nanoscience through topics that can be integrated into the existing introductory physics or teacher training courses. The experimental themes include two teaching models of an atomic force microscope (AFM) and an experiment with an elastic optical grating. They are all based on simple experiments that give also quantitative results and can be explained using basic physics theory.

  6. Themes of nanoscience for the introductory physics course

    Energy Technology Data Exchange (ETDEWEB)

    Planinsic, Gorazd [Faculty for Mathematics and Physics, University of Ljubljana (Slovenia); Lindell, Anssi [Department of Teacher Education, University of Jyvaskyla (Finland); Remskar, Maja [Josef Stefan Institute, Ljubljana (Slovenia)

    2009-07-15

    We present three experimental themes and one discussion theme that proved to be suitable for introducing nanoscience through topics that can be integrated into the existing introductory physics or teacher training courses. The experimental themes include two teaching models of an atomic force microscope (AFM) and an experiment with an elastic optical grating. They are all based on simple experiments that give also quantitative results and can be explained using basic physics theory.

  7. New Themes in Physics Teaching: A personal retrospective

    OpenAIRE

    Dykstra, Dewey

    2012-01-01

    For a little over 40 years, what we label now, physics education research, has been conducted.  As a result, new themes in the research in physics learning and in physics education have emerged.  Some of these themes are cognitivism, qualitative research, learning as construction of knowledge, epistemological underpinnings that are not realist, student understanding-driven pedagogies, and scholarship in fields outside physics.  These themes have arisen in minds of our colleagues, who focus th...

  8. Globalisation of commercial theme parks: the walt Disney Company

    OpenAIRE

    DE GROOTE, Patrick

    2009-01-01

    The Economics Research Associates (ERA) defines a theme park as ‘A gated attraction that contains rides and/or shows in a themed environment, offers a pay-one-price ticket for its guests and attracts at least 500,000 annual visits’ (ERA, 2007). A more detailed description for theme parks is given by Philip L. Pearce (in Jafar Jafari, 2000, 124-5): ‘Theme parks are capital intensive, highly developed, self-contained recreational spaces which invariably charge admission. The entertainment, ride...

  9. Theme-Based Bidisciplinary Chemistry Laboratory Modules

    Science.gov (United States)

    Leber, Phyllis A.; Szczerbicki, Sandra K.

    1996-12-01

    A thematic approach to each of the two introductory chemistry laboratory sequences, general and organic chemistry, not only provides an element of cohesion but also stresses the role that chemistry plays as the "central science" and emphasizes the intimate link between chemistry and other science disciplines. Thus, in general chemistry the rubric "Environmental Chemistry" affords connections to the geosciences, whereas experiments on the topic of "Plant Assays" bridge organic chemistry and biology. By establishing links with other science departments, the theme-based laboratory experiments will satisfy the following multidisciplinary criteria: (i) to demonstrate the general applicability of core methodologies to the sciences, (ii) to help students relate concepts to a broader multidisciplinary context, (iii) to foster an attitude of both independence and cooperation that can transcend the teaching laboratory to the research arena, and (iv) to promote greater cooperation and interaction between the science departments. Fundamentally, this approach has the potential to impact the chemistry curriculum significantly by including student decision-making in the experimental process. Furthermore, the incorporation of GC-MS, a powerful tool for separation and identification as well as a state-of-the-art analytical technique, in the modules will enhance the introductory general and organic chemistry laboratory sequences by making them more instrument-intensive and by providing a reliable and reproducible means of obtaining quantitative analyses. Each multifaceted module has been designed to meet the following criteria: (i) a synthetic protocol including full spectral characterization of products, (ii) quantitative and statistical analyses of data, and (iii) construction of a database of results. The database will provide several concrete functions. It will foster the idea that science is a continuous incremental process building on the results of earlier experimentalists

  10. A Qualitative Analysis of Stress and Relaxation Themes Contributing to Burnout in First-Year Psychiatry and Medicine Residents.

    Science.gov (United States)

    Benson, Nicole M; Chaukos, Deanna; Vestal, Heather; Chad-Friedman, Emma F; Denninger, John W; Borba, Christina P C

    2018-05-14

    Qualitative research on trainee well-being can add nuance to the understanding of propagators of burnout, and the role for interventions aimed at supporting well-being. This qualitative study was conducted to identify (i) situations and environments that cause stress for trainees, (ii) stress-reducing activities that trainees utilize, and (iii) whether trainees who report distress (high burnout and depression scores) describe different stressors and relaxation factors than those who do not. The study was conducted with a convenience sample of first-year medicine and psychiatry residents at a large urban teaching hospital. Participants were asked to complete electronic stress and relaxation diaries daily for 1 week. Diary entries were coded for recurrent themes. Participants were screened for burnout and depression. Codes were compared by subgroup based on baseline burnout and depression status to elucidate if specific themes emerged in these subgroups. Study sample included 51 interns. Sixteen (16/50, 32%) screened positive for burnout and three (3/50, 14%) had a positive depression screen. The most common stressors related to aspects of the learning environment, compounded by feeling under-equipped, overwhelmed, or out of time. The majority of relaxation activities involved social connection, food, other comforts, and occurred outside of the hospital environment. This study reveals that interns (regardless of burnout or depression screen) identify stressors that derive primarily from organizational, interpersonal, and cultural experiences of the learning environment; whereas relaxation themes are diversely represented across realms (home, leisure, social, health), though emphasize activities that occur outside of the work place.

  11. Celestial-themed Cartoons Captivate Children

    Science.gov (United States)

    Cappelli, V.; di Benedetto, C.

    2010-12-01

    Attivamente: Big discoveries with Galileo and Phineas & Ferb, an educational entertainment project for children, was a collaboration between Disney Television Italy and the Education and Public Outreach office of the INAF Astronomical Observatory of Padua, Italy. The project started during the International Year of Astronomy 2009 and came to an end in June 2010. It consisted of a cartoon series, several articles in a Disney magazine and an educational kit focused on Galileo Galilei and the Moon. The kit, called the First Astronomical Kit, was distributed to 30 000 children in Italy, and included a board game about the Moon, an observation diary and a lunar fact card. The aim of the kit was to give children some basic astronomical knowledge and to demonstrate the essential role that observation plays in understanding the heavens. This article discusses how a research institute and a major entertainment company -- each with very different working practices -- were able to work together to form a successful partnership.

  12. Strategic Themes in the Haulier Business

    DEFF Research Database (Denmark)

    Borgström, Benedikte; Gammelgaard, Britta; Wieland, Andreas

    2017-01-01

    Purpose: This article provides a comprehensive review of the strategic management of transport and logistics services and to identify promising avenues for future research in the field. Design/methodology/approach: A systematic literature review is conducted based on articles published between 2011......: In highly ranked transport journals, only two per cent of the published articles concern haulier strategizing, thus, knowledge development concerning the socio-economic and managerial problems of practitioners and policy makers is delimited. Original/value: The study contributes to a strategic perspective...

  13. Electronic Commerce: Themes, Concepts and Relationships

    Directory of Open Access Journals (Sweden)

    Kuo-Hsun Yu

    2008-12-01

    Full Text Available In this paper, bibliometric (co-citation analysis and social network analysis techniques are used to investigate the intellectual pillars of the electronic commerce literature as reported in SSCI and SCI journals between 2002 and 2006. By analyzing 22,760 citations of 840 articles, this study maps an invisible network of knowledge of electronic commerce studies. The results of the mapping can help identify the research direction of electronic commerce research and provide a valuable tool for researchers to access the literature in this area.

  14. Extreme Cost Growth: Themes from Six U.S. Air Force Major Defense Acquisition Programs

    Science.gov (United States)

    2015-01-01

    See for example Linda D. Koontz , Polar Orbiting Environmental Satellites: Status, Plans, and Future Data Management Challenges, testimony before the...University Press, 2015. Koontz , Linda D., Polar-Orbiting Environmental Satellites: Status, Plans, and Future Data Management Challenges, testimony

  15. Understanding electronic social customer relationship management: foundations and current major themes

    NARCIS (Netherlands)

    Constantinides, Efthymios; Yousif, Arsham; de Vries, Sjoerd A.

    2014-01-01

    Empowered customers, global competition and a persistent financial crisis are important reasons driving businesses to new approaches for building and maintaining competitive advantages. Breaking away from the past focus on internal sources of competitive advantage strategists are switching attention

  16. Exploring themes and challenges in developing sustainable supply chains – A complexity theory perspective

    DEFF Research Database (Denmark)

    Abbasi, Maisam

    identify, classify, and tackle the challenges that can hinder the execution of such strategies. To develop innovative strategies, the patterns of current trends and themes need to be learned and the missing ones need to be identified. The purpose of this research was to explore themes and challenges......To develop sustainable supply chains in a way that their negative environmental and social effects are minimized, shortand long-term targets should be set. The transformation of supply chains towards these targets calls for the development of innovative strategies and the need to continuously...... in developing sustainable supply chain activities from theoretical and empirical perspectives. Six research studies (RS) were designed and carried out. Two explored the patterns of the themes and challenges in making supply chains environmentally and socially sustainable in general (RS1, RS2). One explored...

  17. Scenario Archetypes: Converging Rather than Diverging Themes

    Directory of Open Access Journals (Sweden)

    Jon P. Sadler

    2012-04-01

    Full Text Available Future scenarios provide challenging, plausible and relevant stories about how the future could unfold. Urban Futures (UF research has identified a substantial set (>450 of seemingly disparate scenarios published over the period 1997–2011 and within this research, a sub-set of >160 scenarios has been identified (and categorized based on their narratives according to the structure first proposed by the Global Scenario Group (GSG in 1997; three world types (Business as Usual, Barbarization, and Great Transitions and six scenarios, two for each world type (Policy Reform—PR, Market Forces—MF, Breakdown—B, Fortress World—FW, Eco-Communalism—EC and New Sustainability Paradigm—NSP. It is suggested that four of these scenario archetypes (MF, PR, NSP and FW are sufficiently distinct to facilitate active stakeholder engagement in futures thinking. Moreover they are accompanied by a well-established, internally consistent set of narratives that provide a deeper understanding of the key fundamental drivers (e.g., STEEP—Social, Technological, Economic, Environmental and Political that could bring about realistic world changes through a push or a pull effect. This is testament to the original concept of the GSG scenarios and their development and refinement over a 16 year period.

  18. THE CRUCIAL THEMES OF EU ENLARGEMENT

    Directory of Open Access Journals (Sweden)

    Jacques Pelkmans

    2001-12-01

    Full Text Available This article provides a critical review of the “terms” of the ongoing EU enlargement, in the light of the European public interest. The European public interest ought to include the prospective (Central European members, within a perspective of an enlarged Union in 2010, or so. The following forms a personalised summary of a major report published (in Dutch in September 2001 by the WRR in The Hague (a think-tank, formally under the Dutch Prime Minister, but by statute fully independent. The author was one of the lead-writers of this report. The present article merely focuses on the policy recommendations of the report. It is hoped that these kinds of critical analyses will help to stimulate solid policy debate on the EU in Romania, on the road to EU membership. The article discusses why the notion of a “core-acquis” would improve the enlargement strategy; the application of the core acquis to the internal market, environment and justice and home affairs; judicial and administrative capacity; accession to “euro-land”; the rapid reform of the CAP; a reform of “cohesion” approaches; and a note on the EU budgetary implications.

  19. Generativity and Themes of Agency and Communion in Adult Autobiography.

    Science.gov (United States)

    Mansfield, Elizabeth D.; McAdams, Dan P.

    1996-01-01

    Examines differences between 70 more- and less-generative adults through a new coding system for analyzing themes of agency and communion in significant life-story scenes. The study revealed that highly generative adults express greater levels of the communion themes of dialog and care/help and greater levels of agency/communion integration. (LSR)

  20. Death Related Themes in Anorexia Nervosa: A Practical Exploration.

    Science.gov (United States)

    Russell, Janice; And Others

    1990-01-01

    Explored death-related themes in psychodynamic etiology of anorexia nervosa by comparing anorexic adolescent patients (n=28) to age-matched controls (n=238). Results suggest that death-related themes are of significance in the understanding and management of anorexia nervosa. (Author/ABL)

  1. Reinventing spatial planning in a borderless Europe : Emergent themes

    NARCIS (Netherlands)

    Waterhout, B.; Faludi, A.K.F.; Stead, D.; Zonneveld, W.; Milder, J.; Nadin, V.

    2009-01-01

    This paper is a follow-up to the Chicago Round Table ‘Emergent Research Themes on European Territorial Governance’ in 2008 questioning the view of EU territory as the sum of mutually exclusive territories under nation-state control and pointing out the existence of overlapping jurisdictions. Themes

  2. Teaching Public Administration: Key Themes 1996-2016

    Science.gov (United States)

    Fenwick, John

    2018-01-01

    In this article, the aim is to explore some of the key themes to emerge in the journal during the past two decades. Each selected theme will be reviewed in the light of issues raised in particular papers. The aim of this approach is, first, to facilitate reflection upon the contribution of the journal as its subject matter has moved from a concern…

  3. Supernatural Themes in Selected Children's Stories of Isaac Bashevis Singer.

    Science.gov (United States)

    Schlessinger, June H.; Vanderryst, June D.

    1989-01-01

    Discusses the impact of the traditional folklore theme of good versus evil on children's development and analyzes the development of this theme using magical and supernatural situations in the work of Isaac Bashevis Singer. A selected bibliography of work by and literary criticisms of Singer's writings is provided. (five references) (CLB)

  4. The New Nuffield Combined Science Themes for the Middle Years

    Science.gov (United States)

    Bingham, C. D.

    1976-01-01

    Described are the development, materials, and use of English developed science activities for junior high schools, the Nuffield Combined Science Themes for the Middle Years. The program, when completed will present 24 themes including: color, water, air, plastics, metals, insects, food, light, and electricity. (SL)

  5. Complex, Dynamic Systems: A New Transdisciplinary Theme for Applied Linguistics?

    Science.gov (United States)

    Larsen-Freeman, Diane

    2012-01-01

    In this plenary address, I suggest that Complexity Theory has the potential to contribute a transdisciplinary theme to applied linguistics. Transdisciplinary themes supersede disciplines and spur new kinds of creative activity (Halliday 2001 [1990]). Investigating complex systems requires researchers to pay attention to system dynamics. Since…

  6. New Themes in Physics Teaching: A Personal Retrospective

    Science.gov (United States)

    Dykstra, Dewey I., Jr.

    2012-01-01

    For a little over 40 years, what we label now physics education research has been conducted. As a result, a new type of theme in the research and in physics education has emerged. Some of these themes are cognitivism, research as qualitative, learning as construction of knowledge, theoretical underpinnings that are not realist, student-centered…

  7. Major depression

    Science.gov (United States)

    Depression - major; Depression - clinical; Clinical depression; Unipolar depression; Major depressive disorder ... providers do not know the exact causes of depression. It is believed that chemical changes in the ...

  8. Examining Kindergarteners' Drawings for Their Perspectives on Picture Books' Themes and Characters

    Science.gov (United States)

    Hsiao, Ching-Yuan; Chen, Chi-Mei

    2015-01-01

    The aim of this study was to identify and characterize children's perspectives on a picture book's themes and characters by examining their drawings. The study was conducted over a five-month period in a public kindergarten in southern Taiwan, with six children aged 5-6 years. Picture book appreciation activities focused on eight picture books.…

  9. [Evaluation standards and application for photography of schistosomiasis control theme].

    Science.gov (United States)

    Chun-Li, Cao; Qing-Biao, Hong; Jing-Ping, Guo; Fang, Liu; Tian-Ping, Wang; Jian-Bin, Liu; Lin, Chen; Hao, Wang; You-Sheng, Liang; Jia-Gang, Guo

    2018-02-26

    To set up and apply the evaluation standards for photography of schistosomiasis control theme, so as to offer the scientific advice for enriching the health information carrier of schistosomiasis control. Through the literature review and expert consultation, the evaluation standard for photography of schistosomiasis control theme was formulated. The themes were divided into 4 projects, such as new construction, natural scenery, working scene, and control achievements. The evaluation criteria of the theme photography were divided into the theme (60%), photographic composition (15%), focus exposure (15%), and color saturation (10%) . A total of 495 pictures (sets) from 59 units with 77 authors were collected from schistosomiasis epidemic areas national wide. After the first-step screening and second-step evaluation, the prizes of 3 themes of control achievements and new construction, working scene, and natural scenery were selected, such as 6 pictures of first prize, 12 pictures of second prize, 18 pictures of third prize, and 20 pictures of honorable prize. The evaluation standards of theme photography should be taken into the consideration of the technical elements of photography and the work specification of schistosomiasis prevention and control. In order to improve the ability of records for propaganda purpose of schistosomiasis control and better play a role of guiding correct propaganda, the training and guidance of photography of professionals should be carried out.

  10. The use of negative themes in television food advertising.

    Science.gov (United States)

    Pettigrew, Simone; Roberts, Michele; Chapman, Kathy; Quester, Pascale; Miller, Caroline

    2012-04-01

    The ability of food advertising to trigger food consumption and influence social norms relating to food consumption has resulted in increasing attention being given to the prevalence and nature of food advertising. The present study investigated the use of negative themes in food advertisements aired on Australian television to determine the prevalence of depictions of violence/aggression, mocking, nagging, boredom, loneliness, food craving, mood enhancement, and the emotional use of food across 61 days of programming time. The results suggest that advertisers are using negative themes to capture attention and invoke an emotional response in the target audience. Sixteen percent (14,611) of the 93,284 food advertisements contained negative themes, with mood enhancement and food craving being the most commonly depicted negative themes. Advertisements with negative themes were more likely to be for non-core foods and to be aired during children's popular viewing times than at other times. The potential for negative themes in food advertising to promote unhealthy food consumption behaviors among children is likely to be of concern to policy makers. Building on this exploratory study, further research is needed to investigate how nutrition-related decision making is affected by exposure to food advertisements employing negative emotional themes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Detecting Themed Streets Using a Location Based Service Application

    Directory of Open Access Journals (Sweden)

    Byeongsuk Ji

    2016-07-01

    Full Text Available Various themed streets have recently been developed by local governments in order to stimulate local economies and to establish the identity of the corresponding places. However, the motivations behind the development of some of these themed street projects has been based on profit, without full considerations of people’s perceptions of their local areas, resulting in marginal effects on the local economies concerned. In response to this issue, this study proposed a themed street clustering method to detect the themed streets of a specific region, focusing on the commercial themed street, which is more prevalent than other types of themed streets using location based service data. This study especially uses “the street segment” as a basic unit for analysis. The Sillim and Gangnam areas of Seoul, South Korea were chosen for the evaluation of the adequacy of the proposed method. By comparing trade areas that were sourced from a market analysis report by a reliable agent with the themed streets detected in this study, the experiment results showed high proficiency of the proposed method.

  12. Identifying Themes for Research-Based Development of Pedagogy and Guidance in Higher Education

    Science.gov (United States)

    Jääskelä, Päivikki; Nissilä, Pia

    2015-01-01

    The high value accorded to the research-based development of education in higher education communities means that researchers in the field have an important role in determining the foci of such efforts. However, it is important to ask whether higher education research is providing answers that satisfy practical educational needs. In this study,…

  13. Ask an Anatomist: Identifying Global Trends, Topics and Themes of Academic Anatomists Using Twitter

    Science.gov (United States)

    Marsland, Madeleine J.; Lazarus, Michelle D.

    2018-01-01

    Social media (SoMe) is increasingly used in higher education (HE) to access knowledge and enable global communication. The SoMe platform Twitter® is particularly beneficial in these contexts because it is readily accessible, easily searchable (via hashtags) and global. Given these advantages, the twitter platform @AskAnatomist was created to…

  14. Major Development Communication Paradigms and Practices ...

    African Journals Online (AJOL)

    info

    major paradigms of development and communication practices on graphic ... mobilize, educate and persuade target audience to support human development ... facilitates the understanding of the themes, issues and facts of a campaign.

  15. Measuring the operational efficiency of individual theme park attractions.

    Science.gov (United States)

    Kim, Changhee; Kim, Soowook

    2016-01-01

    This study assesses the operation efficiency of theme park attractions using the data envelopment analysis, utilizing actual data on 15 attractions at Samsung Everland located in Yongin-si, Republic of Korea. In particular, this study identifies crowding and waiting time as one of the main causes of visitor's satisfaction, and analyzes the efficiency of individual attractions in terms of waiting time. The installation area, installation cost, and annual repair cost are set as input factors and the number of annual users and customer satisfaction as output factors. The results show that the roller coaster-type attractions were less efficient than other types of attractions while rotating-type attractions were relatively more efficient. However, an importance performance analysis on individual attraction's efficiency and satisfaction showed that operational efficiency should not be the sole consideration in attraction installation. In addition, the projection points for input factors for efficient use of attractions and the appropriate reference set for benchmarking are provided as guideline for attraction efficiency management.

  16. The Future of Organization Design: An Interpretative Synthesis in Three Themes

    Directory of Open Access Journals (Sweden)

    Richard M. Burton

    2013-04-01

    Full Text Available In the inaugural issue of the Journal of Organization Design (Vol. 1, #1, 2012, noted scholars and experienced practitioners presented their views on the future of organization design. The seven wise and provocative statements were subsequently discussed by members of the Organizational Design Community at a conference held at Harvard University on August 3, 2012. I was asked by JOD to monitor the discussion and identify the broad organization design themes that emerged. Although the discussion was wide ranging, three themes were noticeable. The first theme is that there are fundamentals of organization design, and all agreed that design involves creating a cohesive socio-technical system from a number of constituent elements. The second theme is that the boundaries of many newer organizational forms extend beyond that of the single firm, so the scope of organization design needs to expand to include ecosystems, collaborative communities, industries, and other supra-firm architectures. The third theme involves time and change, requiring a shift in focus from how organizations become stable and predictable to how they can become more agile.

  17. A Foundation for Mobile User Experiences in Theme Parks

    DEFF Research Database (Denmark)

    Østergaard, Claus Møller

    2013-01-01

    Based on case studies, this paper proposes a theoretical understanding of three essential aspects, which affect mobile user experiences in theme parks. The aspect are (a) the controllability of the mobile content, (b) the balance in the hybrid space of proximate physical place and remote digital...... space, and (c) the social space. Furthermore, the social space is exceptionally important in understanding mobile user experiences in theme parks. Thus, this paper proposes to extract the social space from the physical place. This means, that mobile user experiences in theme parks can be understood...

  18. Traffic Accident Investigation: A Suitable Theme for Teaching Mechanics.

    Science.gov (United States)

    Tao, P. K.

    1987-01-01

    Suggests the development of curriculum materials on the applications of physics to traffic accident investigations as a theme for teaching mechanics. Describes several standard investigation techniques and the physics principles involved, along with some sample exercises. (TW)

  19. Theme: The Role of Science in the Agricultural Education Curriculum.

    Science.gov (United States)

    Agricultural Education Magazine, 2002

    2002-01-01

    Thirteen theme articles discuss integration of science and agriculture, the role of science in agricultural education, biotechnology, agriscience in Tennessee and West Virginia, agriscience and program survival, modernization of agricultural education curriculum, agriscience and service learning, and biotechnology websites. (SK)

  20. Introducing the JMBE Themed Issue on Scientific Citizenship

    Directory of Open Access Journals (Sweden)

    Jack A. Gilbert

    2016-01-01

    Full Text Available In this Editorial, the three Guest Editors for JMBE's first standalone themed issue introduce the topic of scientific citizenship and provide an overview of the current ideas and best practices contained within the issue. 

  1. The historical theme in the poetry of Esenin

    Directory of Open Access Journals (Sweden)

    Hunarikova P. H.

    2016-03-01

    Full Text Available the article examines the historical theme in the poetry of Esenin. The author explores in his work historical problems in poetry Esenin, shows the role of the poet in contemporary Russia.

  2. Franchising Theme Parks : Disneyland Paris inFocus

    OpenAIRE

    Kocsis, Kinga

    2014-01-01

    The report consisted of the analysis of theoretical frameworks of franchise and using franchising as a promotional method of theme parks. The definition of franchise and the use, right and regulations of it are essential knowledge to understand the base of franchise based theme parks. Also it was analyzed how franchising affects tourism in specific fields of existing franchises. The role of a franchise in our society and its values was also taken into consideration. The values and the role of...

  3. Underdeveloped Themes in Qualitative Research: Relationship With Interviews and Analysis.

    Science.gov (United States)

    Connelly, Lynne M; Peltzer, Jill N

    2016-01-01

    In this methodological article, the authors address the problem of underdeveloped themes in qualitative studies they have reviewed. Various possible reasons for underdeveloped themes are examined, and suggestions offered. Each problem area is explored, and literature support is provided. The suggestions that are offered are supported by the literature as well. The problem with underdeveloped themes in certain articles is related to 3 interconnected issues: (a) lack of clear relationship to the underlying research method, (b) an apparent lack of depth in interviewing techniques, and (c) lack of depth in the analysis. Underdeveloped themes in a qualitative study can lead to a lack of substantive findings that have meaningful implications for practice, research, and the nursing profession, as well as the rejection of articles for publication. Fully developed themes require knowledge about the paradigm of qualitative research, the methodology that is proposed, the effective techniques of interviewing that can produce rich data with examples and experiences, and analysis that goes beyond superficial reporting of what the participants have said. Analytic problem areas include premature closure, anxiety about how to analyze, and confusion about categories and themes. Effective qualitative research takes time and effort and is not as easy as is sometimes presumed. The usefulness of findings depends on researchers improving their research skills and practices. Increasingly researchers are using qualitative research to explore clinically important issues. As consumers of research or members of a research team, clinical nurse specialists need to understand the nature of this research that can provide in-depth insight and meaning.

  4. Promising Themes for Antismoking Campaigns Targeting Youth and Young Adults.

    Science.gov (United States)

    Brennan, Emily; Gibson, Laura A; Kybert-Momjian, Ani; Liu, Jiaying; Hornik, Robert C

    2017-01-01

    Behavior change campaigns typically try to change beliefs that influence behaviors, with targeted beliefs comprising the campaign theme. We present an empirical approach for choosing among a large number of potential themes, and results from the implementation of this approach for campaigns aimed at 4 behavioral targets: (1) preventing smoking initiation among youth, and (2) preventing initiation, (3) stopping progression to daily smoking and (4) encouraging cessation among young adults. An online survey of 13- to 17-year-olds and 18- to 25-year-olds in the United States (US), in which 20 potential campaign themes were represented by 154 beliefs. For each behavioral target, themes were ranked based on the strength of belief-intention and belief-behavior associations and size of the population not already endorsing the beliefs. The most promising themes varied across behavioral targets but 3 were consistently promising: consequences of smoking for mood, social acceptance and social popularity. Using a robust and systematic approach, this study provides campaign developers with empirical data to inform their selection of promising themes. Findings related to the campaign to prevent initiation among youth informed the development of the US Food and Drug Administration's "The Real Cost" campaign.

  5. Success stories and emerging themes in conservation physiology

    Science.gov (United States)

    Madliger, Christine L.; Cooke, Steven J.; Crespi, Erica J.; Funk, Jennifer L.; Hultine, Kevin R.; Hunt, Kathleen E.; Rohr, Jason R.; Sinclair, Brent J.; Suski, Cory D.; Willis, Craig K. R.; Love, Oliver P.

    2016-01-01

    The potential benefits of physiology for conservation are well established and include greater specificity of management techniques, determination of cause–effect relationships, increased sensitivity of health and disturbance monitoring and greater capacity for predicting future change. While descriptions of the specific avenues in which conservation and physiology can be integrated are readily available and important to the continuing expansion of the discipline of ‘conservation physiology’, to date there has been no assessment of how the field has specifically contributed to conservation success. However, the goal of conservation physiology is to foster conservation solutions and it is therefore important to assess whether physiological approaches contribute to downstream conservation outcomes and management decisions. Here, we present eight areas of conservation concern, ranging from chemical contamination to invasive species to ecotourism, where physiological approaches have led to beneficial changes in human behaviour, management or policy. We also discuss the shared characteristics of these successes, identifying emerging themes in the discipline. Specifically, we conclude that conservation physiology: (i) goes beyond documenting change to provide solutions; (ii) offers a diversity of physiological metrics beyond glucocorticoids (stress hormones); (iii) includes approaches that are transferable among species, locations and times; (iv) simultaneously allows for human use and benefits to wildlife; and (v) is characterized by successes that can be difficult to find in the primary literature. Overall, we submit that the field of conservation physiology has a strong foundation of achievements characterized by a diversity of conservation issues, taxa, physiological traits, ecosystem types and spatial scales. We hope that these concrete successes will encourage the continued evolution and use of physiological tools within conservation-based research and

  6. Success stories and emerging themes in conservation physiology.

    Science.gov (United States)

    Madliger, Christine L; Cooke, Steven J; Crespi, Erica J; Funk, Jennifer L; Hultine, Kevin R; Hunt, Kathleen E; Rohr, Jason R; Sinclair, Brent J; Suski, Cory D; Willis, Craig K R; Love, Oliver P

    2016-01-01

    The potential benefits of physiology for conservation are well established and include greater specificity of management techniques, determination of cause-effect relationships, increased sensitivity of health and disturbance monitoring and greater capacity for predicting future change. While descriptions of the specific avenues in which conservation and physiology can be integrated are readily available and important to the continuing expansion of the discipline of 'conservation physiology', to date there has been no assessment of how the field has specifically contributed to conservation success. However, the goal of conservation physiology is to foster conservation solutions and it is therefore important to assess whether physiological approaches contribute to downstream conservation outcomes and management decisions. Here, we present eight areas of conservation concern, ranging from chemical contamination to invasive species to ecotourism, where physiological approaches have led to beneficial changes in human behaviour, management or policy. We also discuss the shared characteristics of these successes, identifying emerging themes in the discipline. Specifically, we conclude that conservation physiology: (i) goes beyond documenting change to provide solutions; (ii) offers a diversity of physiological metrics beyond glucocorticoids (stress hormones); (iii) includes approaches that are transferable among species, locations and times; (iv) simultaneously allows for human use and benefits to wildlife; and (v) is characterized by successes that can be difficult to find in the primary literature. Overall, we submit that the field of conservation physiology has a strong foundation of achievements characterized by a diversity of conservation issues, taxa, physiological traits, ecosystem types and spatial scales. We hope that these concrete successes will encourage the continued evolution and use of physiological tools within conservation-based research and management

  7. Composing the theme of city to be diverse and sustainable

    Science.gov (United States)

    Wiranegara, H. W.

    2018-01-01

    To give a path for developing a city needs a theme. City’s goal stated in a document of a spatial plan were too broad and insufficient detail in giving a direction. To make more detail and precise, every city has to compose a city theme. It is developed based on the potential, the uniqueness, the excellence, and the sustainability of its human resources, natural resources, and man-made resources. An integration among the three of resources which have the highest score become a theme of the city. The aim of this research was to formulate the conceptual framework to compose a city theme. The research design was the interview survey in Banda Aceh, Banjarmasin, and Kupang. Informants were the government officials, academics, figures, the private sector and public who considered related to the intended information being collected. Having set the conceptual framework, the interview directed to check the implementation in realities. The result was that the conceptual framework could accommodate the phenomenon of composing the theme of the city. Yet, it was a preliminary in nature and needed more research to get a complete result.

  8. Environmental Protection Theme at Discourses of Corporative Social Responsibility

    Directory of Open Access Journals (Sweden)

    Alfredo Rodrigues Leite da Silva

    2009-01-01

    Full Text Available This paper views and discusses discourses on social responsibility in organizations and their use of the environmental theme. We suppose that strategies are used to disseminate some discourses concerning these matters. The ambiguities of themes within organizations point to a fragmented discourse (Fineman, 1996, revealing practices of openness and dissimulation. The theoretical discussion starts with the theme of social responsibility, confronting it with an environmental theme and discusses discourses with ambiguities of organizational practice stemming from two themes. At the end, a case study of Antena completes the discussion. Data was collected with documental research and semi-structured interviews. We made use of Discourse Analysis methodology (Fiorin, 1989. In conclusion, the concern with social responsibility and its environmental thematic lie within the organization. It is found in the discourse and actions at a high administration level including managers and a high number of technical workers. The silence about the limits of this responsibility is fulfilled by a technical workers group that reveals dissimulation when openness menaces some objectives.

  9. Exploratory Analysis of Marketing and Non-marketing E-cigarette Themes on Twitter.

    Science.gov (United States)

    Han, Sifei; Kavuluru, Ramakanth

    2016-11-01

    Electronic cigarettes (e-cigs) have been gaining popularity and have emerged as a controversial tobacco product since their introduction in 2007 in the U.S. The smoke-free aspect of e-cigs renders them less harmful than conventional cigarettes and is one of the main reasons for their use by people who plan to quit smoking. The US food and drug administration (FDA) has introduced new regulations early May 2016 that went into effect on August 8, 2016. Given this important context, in this paper, we report results of a project to identify current themes in e-cig tweets in terms of semantic interpretations of topics generated with topic modeling. Given marketing/advertising tweets constitute almost half of all e-cig tweets, we first build a classifier that identifies marketing and non-marketing tweets based on a hand-built dataset of 1000 tweets. After applying the classifier to a dataset of over a million tweets (collected during 4/2015 - 6/2016), we conduct a preliminary content analysis and run topic models on the two sets of tweets separately after identifying the appropriate numbers of topics using topic coherence. We interpret the results of the topic modeling process by relating topics generated to specific e-cig themes. We also report on themes identified from e-cig tweets generated at particular places (such as schools and churches) for geo-tagged tweets found in our dataset using the GeoNames API. To our knowledge, this is the first effort that employs topic modeling to identify e-cig themes in general and in the context of geo-tagged tweets tied to specific places of interest.

  10. How to Mitigate Theme Park Crowding? A Prospective Coordination Approach

    Directory of Open Access Journals (Sweden)

    Yuguo Yuan

    2018-01-01

    Full Text Available Crowding is a key factor in tourists’ experience in theme parks, and mitigating crowding makes parks more competitive. This study examines how to effectively mitigate crowding in theme parks. First, a Markov-based method is developed to predict the spatial-temporal distribution of tourists in the park. Then, a prospective coordination approach based on the tourist distribution prediction is proposed. To evaluate the performance of this approach, an experiment is constructed using an agent-based simulation platform. The results indicate that the proposed method significantly outperforms existing methods. Furthermore, we conduct two experiments and, based on the results, offer several recommendations for crowd management.

  11. A Literature Analysis of Themes in Paediatric Cochlear Implant Research

    DEFF Research Database (Denmark)

    Hendar, Nils Ola Ebbe; Dammeyer, Jesper Herup

    2015-01-01

    with typical hearing and children with hearing impairment without CI. Published research in the period 1990-2013 on language development was analysed with respect to frequency of selected search terms reflecting different language acquisition themes among children with typical hearing, children with hearing...... impairment without CI, and children with CI, respectively. Results showed a relatively lower number of articles which included themes such as pre-verbal language (imitation, joint attention and gestures), extra lingual abilities (social interaction), and later language skills (semantic, syntactic, grammar...

  12. Editorial for themed issue on ‘Managing the business of cycling’

    OpenAIRE

    Parkin, J.

    2015-01-01

    Cycling is receiving increased attention as a means of addressing urban transport problems. The integration of cycling as a more frequently used mode for all types of trip purpose requires skills in a range of disciplines, including engineering for infrastructure design, as well as planning, ethics, the law, psychology, sociology and health. This editorial sets these papers in the broader context of the subject matter concerned with managing cycling. Four themes are identified as follows: gov...

  13. Exploring Themes and Challenges in Developing Sustainable Supply Chains - A Complexity Theory Perspective

    OpenAIRE

    Abbasi, Maisam

    2014-01-01

    To develop sustainable supply chains in a way that their negative environmental and social effects are minimized, shortand long-term targets should be set. The transformation of supply chains towards these targets calls for the development of innovative strategies and the need to continuously identify, classify, and tackle the challenges that can hinder the execution of such strategies. To develop innovative strategies, the patterns of current trends and themes need to be learned and th...

  14. Delusional Themes Across Affective and Non-Affective Psychoses

    Directory of Open Access Journals (Sweden)

    Angelo Picardi

    2018-04-01

    Full Text Available The current debate about the diagnostic significance of delusion revolves around two positions. The neurocognitive position conceives delusion as a non-specific, though polymorphic, symptom. The psychopathological position views features of delusion such as content and structure as having meaningful connections with diagnostic entities. This study aims at contributing to this debate by examining the association between delusional themes and diagnosis in a sample of 830 adult psychotic patients. All diagnoses were made by experienced psychiatrists according to DSM-IV or ICD-10 criteria, and in 348 patients were established with the SCID-I. All patients were administered the Brief Psychiatric Rating Scale (BPRS. In each patient, the presence of somatic delusions and delusions of guilt, grandiosity, and persecution was determined by examining the scores on relevant BPRS items. Delusions of guilt were almost pathognomonic for a psychotic depressive condition (psychotic major depression 40%; psychotic bipolar depression 30%; depressed schizoaffective disorder 8%; bipolar and schizoaffective mixed states 6 and 7%, respectively. Only 1% of patients with schizophrenia and no patient with delusional disorder or bipolar or schizoaffective manic state showed such delusions. The difference between unipolar and bipolar depression and the other diagnostic groups was highly significant. Delusions of grandiosity characterized mostly patients with manic symptoms (bipolar mania 20%; bipolar mixed states 19%; manic schizoaffective disorder 10%. They were observed significantly more often in bipolar mania than in schizophrenia (7%. Persecutory delusions were broadly distributed across diagnostic categories. However, they were significantly more frequent among patients with schizophrenia and delusional disorder compared with depressed and manic patients. Somatic delusions were also observed in all diagnostic groups, with no group standing out as distinct from the

  15. Major Links.

    Science.gov (United States)

    Henderson, Tona

    1995-01-01

    Provides electronic mail addresses for resources and discussion groups related to the following academic majors: art, biology, business, chemistry, computer science, economics, health sciences, history, literature, math, music, philosophy, political science, psychology, sociology, and theater. (AEF)

  16. Major Roads

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set contains roadway centerlines for major roads (interstates and trunk highways) found on the USGS 1:24,000 mapping series. These roadways are current...

  17. Themes and situations that cause embarrassment among participants in research in which questionnaires or interviews are used

    Directory of Open Access Journals (Sweden)

    Juliana Dias Reis Pessalacia

    2013-03-01

    Full Text Available Objective. To recognize the themes and situations that could make research participants feel embarrassed when questionnaires or interviews are used. Methodology. Quantitative and descriptive study, developed in 2008, involving a stratified sample of 1,1149 subjects who qualified the degree of shame in view of potentially embarrassing themes and situations. Results. For the research participants, it is embarrassing to answer questions related to the following themes: betrayal (50%, physical violence (42%, sexual harassment (42%, psychological violence (40% and death of loved ones (38%. The situations that most frequently causes embarrassment were: start of the survey or interview without requesting informed consent (83%; lack of information about the type of questions that would be addressed (79%, lack of guaranteed anonymity (78%, or use of images (66% or a recorder (58%. Conclusion. Themes and situations were identified that caused embarrassment among participants in research in which questionnaires or interviews were used, which should be considered in the ethical evaluation of studies.

  18. Fine mapping of a dominantly inherited powdery mildew resistance major-effect QTL, Pm1.1, in cucumber identifies a 41.1 kb region containing two tandemly arrayed cysteine-rich receptor-like protein kinase genes.

    Science.gov (United States)

    Xu, Xuewen; Yu, Ting; Xu, Ruixue; Shi, Yang; Lin, Xiaojian; Xu, Qiang; Qi, Xiaohua; Weng, Yiqun; Chen, Xuehao

    2016-03-01

    A dominantly inherited major-effect QTL for powdery mildew resistance in cucumber was fine mapped. Two tandemly arrayed cysteine-rich receptor-like protein kinase genes were identified as the most possible candidates. Powdery mildew (PM) is one of the most severe fungal diseases of cucumber (Cucumis sativus L.) and other cucurbit crops, but the molecular genetic mechanisms of powdery mildew resistance in cucurbits are still poorly understood. In this study, through marker-assisted backcrossing with an elite cucumber inbred line, D8 (PM susceptible), we developed a single-segment substitution line, SSSL0.7, carrying 95 kb fragment from PM resistance donor, Jin5-508, that was defined by two microsatellite markers, SSR16472 and SSR16881. A segregating population with 3600 F2 plants was developed from the SSSL0.7 × D8 mating; segregation analysis confirmed a dominantly inherited major-effect QTL, Pm1.1 in cucumber chromosome 1 underlying PM resistance in SSSL0.7. New molecular markers were developed through exploring the next generation resequenced genomes of Jin5-508 and D8. Linkage analysis and QTL mapping in a subset of the F2 plants delimited the Pm1.1 locus into a 41.1 kb region, in which eight genes were predicted. Comparative gene expression analysis revealed that two concatenated genes, Csa1M064780 and Csa1M064790 encoding the same function of a cysteine-rich receptor-like protein kinase, were the most likely candidate genes. GFP fusion protein-aided subcellular localization indicated that both candidate genes were located in the plasma membrane, but Csa1M064780 was also found in the nucleus. This is the first report of dominantly inherited PM resistance in cucumber. Results of this study will provide new insights into understanding the phenotypic and genetic mechanisms of PM resistance in cucumber. This work should also facilitate marker-assisted selection in cucumber breeding for PM resistance.

  19. Celebrating Love in All Shades: YA Books with LGBTQ Themes

    Science.gov (United States)

    Letcher, Mark, Ed.

    2009-01-01

    In this article, the author highlights outstanding literature written for young adults that contains LGBTQ (lesbian, gay, bisexual, transgender, queer/questioning) themes, or contains LGBTQ characters. One of the most critically hailed books with LGBTQ characters from 2007 was Perry Moore's debut novel, "Hero" (Hyperion). This book won the Lambda…

  20. Rendezvous with the World: Missouri Southern State University's Themed Semesters

    Science.gov (United States)

    Stebbins, Chad

    2011-01-01

    Although most universities emphasize study abroad as the primary vehicle to internationalize the campus, in reality only a small percentage of students actually participate in this endeavor. The internationally themed semesters at Missouri Southern State University (MSSU) reach virtually every student, and provide a global perspective and cultural…

  1. "Community" as a Guiding Theme for the Public Speaking Course

    Science.gov (United States)

    Swenson-Lepper, Tammy

    2012-01-01

    First-year students at many universities find themselves in new communities, with little understanding of how their new university, city, academic, or career communities function. Developing a student's sense of community can have long-term benefits. Using the theme of "Community" in the basic public speaking course provides students with…

  2. Language and Theme Symbiosis: A Stylistic Analysis of use of ...

    African Journals Online (AJOL)

    ... parallelism, balanced construction, figures of speech, idioms, and proverbs to reinforce the themes. The enormous use of titles and aliases and the undue emphasis on their use before people's name not only speak volumes about vainglory but also give the work a touch of humour. The language is etched with meticulous ...

  3. Themes of Idealism and Nostalgia in Negritude Poetry | Okune ...

    African Journals Online (AJOL)

    The central thrust of this paper is on the themes of idealism and nostalgia in Negritude poetry. Some critics regard negritude poetry as being sentimental and idealistic. Though true, this observation may be explained by the fact that the historical antecedence that gave rise to this literacy art form, in the first place, ...

  4. Themes of Death and Violence in Lullabies of Different Countries.

    Science.gov (United States)

    Achte, Kalle; And Others

    1990-01-01

    Lullabies are often divided into songs describing death or funeral of child and songs which threaten child with violence if he/she does not sleep. Survey of lullabies from 26 countries and various ethnic groups revealed that threat songs were more common than lullabies with death themes. Latter were frequent in Finno-Ugris and Slavic cultures, not…

  5. Themes in Spirit Possession in Ugandan Christianity | James ...

    African Journals Online (AJOL)

    . This paper discerns a number of common themes that run through many of these experiences. In particular, sex as a motif for deviance and evil is noted as a common feature of many of the possession stories and all contact with spirits is seen ...

  6. Museums as Theme Parks - A Possible Marketing Approach?

    Directory of Open Access Journals (Sweden)

    Alexandra ZBUCHEA

    2015-09-01

    Full Text Available Museums compete increasingly more with very diverse entertainment providers, such as theme parks, despite the fact that their offer is mainly cultural. Museums have had to be more active and they have had to diversify their offer, in order to be more popular, therefore to better achieve their complex cultural missions. They should be more “market oriented” and aim to develop their programs according with their visitors’ needs and desires, as well as with the evolutions in the contemporary society.  One answer to this challenge would be the controversial theme parkisation of museums. The paper discusses in what extent the market approach of theme parks could be a viable marketing strategy for museums. It underlines several differences and similarities between the marketing approaches of museums and theme parks, in order to better understand how a museum could preserve its cultural functions, while obtaining economic success. Only the latter would allow it to better develop its cultural activity and thus to better serve its visitors and the community.

  7. New Themes and Approaches in Second Language Motivation Research.

    Science.gov (United States)

    Dornyei, Zoltan

    2001-01-01

    Provides an overview of the current themes and research directions in second language motivation research. Argues that the initial research inspiration and standard-setting empirical work on second language motivation originating from Canada has borne fruit by educating a new generation of international scholars who have created a colorful mixture…

  8. Further themes in Christian drama in Nigeria | Agoro | EJOTMAS ...

    African Journals Online (AJOL)

    We have used the following plays to illustrate the themes we are going to discuss in this paper: Cold Wings of Darkness and The Living Dead by A.E Anigala, Trial of the Beautiful Ones by Catherine Acholonu,The Secrets of the Devil, The beginning of the End and The Last Generation by Mike Bamiloye,The Church is the ...

  9. The Great Pyramid Builders: An Integrated Theme on Ancient Egypt

    Science.gov (United States)

    Stone, Brian

    2008-01-01

    This article describes a themed classroom project designed to teach about the culture and civilization of ancient Egypt. In preparing the project, it is noted that teachers should remember that different learning styles, including activities that provide meaningful experiences, are appropriate in accommodating the various ways children learn.…

  10. Reading LGBT-Themed Literature with Young People: What's Possible?

    Science.gov (United States)

    Clark, Caroline T.; Blackburn, Mollie V.

    2009-01-01

    The authors' belief that using LGBT (lesbian, gay, bisexual and transgender)-themed literature in schools is possible and necessary, coupled with students' sense that either it cannot or is not being done, prompted them to write this article. While the authors are sympathetic with students' perspectives, and agree that examples are limited, such…

  11. Using Sustainability Themes and Multidisciplinary Approaches to Enhance STEM Education

    Science.gov (United States)

    Rogers, Michael; Pfaff, Thomas; Hamilton, Jason; Erkan, Ali

    2015-01-01

    Purpose: The purpose of this paper is to report on the Multidisciplinary Sustainability Education Project (MSEP) as a framework using sustainability-themed education modules to introduce students to the need for multidisciplinary approaches to solving twenty-first-century problems while retaining traditional course strengths and content.…

  12. Tourism and Water: Themes of the Alpine Convention

    Science.gov (United States)

    Imhof, R.

    2012-04-01

    environment. This needs to be accomplished by balancing the local population's interests with environmental needs. Water is considered as a crucial element for different uses such as hydroelectricity production, irrigation or drinking water as well as in biotopes, especially forests, environmental regeneration and diversity and in natural and cultural landscapes features. Aspects of water protection can be found in the protocols on Energy, Nature Conservation and Landscape Protection, Soil Protection, Tourism, Spatial Planning and Sustainable Development, Mountain Agriculture, Mountain Forests and Transport. However a specific protocol on water is not in place. The Reports on the state of the Alps are published regularly by the Alpine Conference. In November 2006 water was chosen as the topic for the second Report on the State of the Alps. The report compiles information from the Alpine Countries on monitoring programmes, chemical quality of water (point sources, diffuse sources and the chemical status of surface and groundwater in the Alps), water abstraction, residual water and hydro-peaking, droughts and water scarcity, reservoirs and regulated lakes as well on river morphology and continuity. Finally, it summarizes information on property rights and provisions for access to water in the different countries, charges regarding the use of water, different management systems for water supply (public or private), hydro power generation in the Alps and water use management conflicts. The Report was adopted by the Ministers during the Xth Alpine Conference in Evian (France) in 2009. This Conference additionally set up a platform on Water management in the Alpine area in order to deal continually with the theme of water in the Alps. Within this platform, objectives that were identified in the second Report on the State of the Alps should be pursued and examples of good practices exchanged. The platform developed inter alia common guidelines for the use of small hydropower in the

  13. Green Logistic Practices: A Theoretical Approach of the Theme

    Directory of Open Access Journals (Sweden)

    Emanuele Engelage

    2016-12-01

    Full Text Available This study aims to identify the main practices of green logistic considered in national and international academic literature. Using standard techniques for selection of previous studies, this study firts presents the definition of green logistic term in order to differentiate it from other concepts commonly treated similarly, as circular economy, the green chain management (GSCM, the reverse logistics and the environmental certifications (ISO 14001, to obtain clarity about their delimitations, scopes and depth. The study also organizes a taxonomy that involves different functional areas of the company, giving direction to the sustainable conduct, resulting in nine components of green logistic that serve as subsidy for the classification of the identified practices. Based on this conceptual definition and taxonomy, lists 112 practices of green logistic, among which 85 are enterprise ambit, 24 governmental and 3 towards consumers. Regarding the quantity of identified practices and the number of citations, both in business sphere as well as in governmental, the most representative part is related to green  Among the most cited practices are the search by more efficient deliveries, using intermodal and multimodal transport that are less polluting and the programming and optimization of flows deliveries. The survey also revealed that although the concept of green logistics is consolidated in the literature, the majority of studies, especially the empirical, concentrates on some of its components, in particular transport and reverse logistic.

  14. THE FIVE-COLOR THEME IN DONGBA SCRIPTURES

    Directory of Open Access Journals (Sweden)

    Xu Duoduo 许多多

    2018-05-01

    Full Text Available I compared the two translated versions of The Advent of Dragons collected during fieldwork with a Ruke Dongba priest and found many inconsistencies in the same scripture and even within single verses. These inconsistencies may derive from oral composition mechanisms, for example, the aim to adapt the content to metric patterns. These complexities are mainly attested in verses related to the five-color theme, in which the five colors correspond to the mythical creatures and landscape in the five spatial directions. In the formulaic tradition of Dongba Culture, this color-related theme is delivered as a whole message produced by mentioning several keywords. However, the various details involving the keywords do not affect the meaning of the message. Consequently, the flexibilities of the content, highlighted as inconsistencies in the word-by-word translation, leave space for variants in the development of the oral culture and become formularized in various branches of Dongbaism.

  15. Smashing WordPress Themes Making WordPress Beautiful

    CERN Document Server

    Hedengren, Thord Daniel

    2011-01-01

    The ultimate guide to WordPress Themes - one of the hottest topics on the web today WordPress is so much more than a blogging platform, and Smashing WordPress Themes teaches readers how to make it look any way they like - from a corporate site, to a photography gallery and moreWordPress is one of the hottest tools on the web today and is used by sites including The New York Times, Rolling Stone, flickr, CNN, NASA and of course Smashing MagazineBeautiful full colour throughout - web designers expect nothing lessSmashing Magazine will fully support this book by by promoting it through their webs

  16. From themes to hypotheses: following up with quantitative methods.

    Science.gov (United States)

    Morgan, David L

    2015-06-01

    One important category of mixed-methods research designs consists of quantitative studies that follow up on qualitative research. In this case, the themes that serve as the results from the qualitative methods generate hypotheses for testing through the quantitative methods. That process requires operationalization to translate the concepts from the qualitative themes into quantitative variables. This article illustrates these procedures with examples that range from simple operationalization to the evaluation of complex models. It concludes with an argument for not only following up qualitative work with quantitative studies but also the reverse, and doing so by going beyond integrating methods within single projects to include broader mutual attention from qualitative and quantitative researchers who work in the same field. © The Author(s) 2015.

  17. The moral theme in Zulu literature: a progression

    Directory of Open Access Journals (Sweden)

    M. Marggraff

    1998-04-01

    Full Text Available A moral theme in literature is not only unique to Zulu literature. Despite the relative youth of the modern branch of Zulu literature, any observer can make the interesting and important discovery that the moral theme is predominantly conveyed by the following three literary types: the folktale, the moral story, the detective story. The folktale, belonging to traditional literature, is a very well-developed form, that formed the principal means of teaching both children and adults about good and evil. The birth of modern Zulu literature in 1930 brought with it the emergence of the moral story, a literary type in which good triumphs over evil and in which justice prevails. Further development and changes have led to the appearance of the detective story in which crimes are solved and bad people are punished. This progression has developed due to ever-changing circumstances and a need for relevance.

  18. ‘Feeling of despair’ as the leading cluster theme of conceptual descriptive analyses in participatory assessment: Russia Oxfam GB case study

    Directory of Open Access Journals (Sweden)

    Venera Zakirova

    2016-12-01

    Full Text Available This article provides a case study on participatory assessment based on experience gained from an EU–Oxfam GB project entitled “Empowering Municipalities to Effectively Address Poverty” conducted in five small towns in Russia. Participatory assessment through focus group discussions (FGDs was the main approach used in the implementation of the project. A participatory assessment was performed through 25 FGDs in five remote areas in central Russia. More than 200 participants representing people living in poverty, such as single mothers, people with disabilities, families with many children, families with disabled children, and pensioners, voluntarily participated in the meetings. Most of the participants were women (75% aged between 25 and 70 years. We consider that the participants’ representation is relevant in accordance with the official poverty studies. Through identification of patterns of recurrent ideas and opinions, a qualitative method helps us understand social phenomena from the views of and on the basis of the opinions of the participants. The FGDs’ narratives underwent pattern analysis, resulting in the framing of the cluster themes and narrative conceptualization. Cluster analysis of the FGDs’ narratives led to the framing of 10 cluster themes of importance, followed by conceptual descriptions and related narratives. The conceptual description of the leading theme, feeling of despair (theme 1, was described by respondents’ expressions/narratives, such as “Nobody needs us and there is no future for us and our children in this town,” the narrative idea that crosscuts the subsequent themes. The following nine themes are of equal importance, are interlinked, and for the major part constitute the leading theme, feeling of despair (theme 1: state social and family support (theme 2; health care (theme 3; who are those living in poverty? (theme 4; housing (theme 5; living costs (theme 6; employment (theme 7; children

  19. Terror Park: A future theme park in 2100

    OpenAIRE

    Wright, Daniel

    2017-01-01

    In the future, tourism and entertainment could be displayed as spectacles of horror, where consumers are offered and opportunity to revisit the tragedies of the past. Current displays of death where the past is exhibited and consumed as fun, scary and as entertainment productions are widespread. The movie industry provides horror to all ages, children can be exposed to the goulash past in various forms, such as the popular book series ‘Horrible Histories’. Theme parks, rides and roller-coaste...

  20. Ecological Economics: Themes, Approaches, and Differences with Environmental Economics

    OpenAIRE

    Jeroen C.J.M. van den Bergh

    2000-01-01

    This provides a short overview of the main themes of ecological economics (EE). It isargued that EE provides a platform that fosters multidisciplinary environmental research bybringing together the core contributing disciplines economics and ecology. In addition, EE isregarded as a pluralistic approach to environmental research that can be set opposite to, and hasindeed developed as a response to, traditional environmental and resource economics. Acomparison of the two fields is presented to ...

  1. Museums as Theme Parks - A Possible Marketing Approach?

    OpenAIRE

    Alexandra ZBUCHEA

    2015-01-01

    Museums compete increasingly more with very diverse entertainment providers, such as theme parks, despite the fact that their offer is mainly cultural. Museums have had to be more active and they have had to diversify their offer, in order to be more popular, therefore to better achieve their complex cultural missions. They should be more “market oriented” and aim to develop their programs according with their visitors’ needs and desires, as well as with the evolutions in the contemporary soc...

  2. Interpreting hegemonic themes in the electronic forró

    Directory of Open Access Journals (Sweden)

    Jean Henrique Costa

    2014-03-01

    Full Text Available Current investigation analyzes hegemonic themes in the music of electronic forró (Brazilian dance. The critical theory of Theodor W. Adorno and Cultural Studies revealed: a the main thematic patterns and clichés of the genre; b the meanings of these thematic patterns; c and some hypothetical implications for the consumer. The above implies certain relations of domination reinforced in and by the consumption of the electronic forró.

  3. Providing long-acting reversible contraception services in Seattle school-based health centers: key themes for facilitating implementation.

    Science.gov (United States)

    Gilmore, Kelly; Hoopes, Andrea J; Cady, Janet; Amies Oelschlager, Anne-Marie; Prager, Sarah; Vander Stoep, Ann

    2015-06-01

    The purpose of this study was to describe the implementation of a program that provides long-acting reversible contraception (LARC) services within school-based health centers (SBHCs) and to identify barriers and facilitators to implementation as reported by SBHC clinicians and administrators, public health officials, and community partners. We conducted 14 semistructured interviews with key informants involved in the implementation of LARC services. Key informants included SBHC clinicians and administrators, public health officials, and community partners. We used a content analysis approach to analyze interview transcripts for themes. We explored barriers to and facilitators of LARC service delivery across and within key informant groups. The most cited barriers across key informant groups were as follows: perceived lack of provider procedural skills and bias and negative attitudes about LARC methods. The most common facilitators identified across groups were as follows: clear communication strategies, contraceptive counseling practice changes, provider trainings, and stakeholder engagement. Two additional barriers emerged in specific key informant groups. Technical and logistical barriers to LARC service delivery were cited heavily by SBHC administrative staff, community partners, and public health officials. Expense and billing was a major barrier to SBHC administrative staff. LARC counseling and procedural services can be implemented in an SBHC setting to promote access to effective contraceptive options for adolescent women. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  4. Integrating Environmental and Human Health Databases in the Great Lakes Basin: Themes, Challenges and Future Directions

    Directory of Open Access Journals (Sweden)

    Kate L. Bassil

    2015-03-01

    Full Text Available Many government, academic and research institutions collect environmental data that are relevant to understanding the relationship between environmental exposures and human health. Integrating these data with health outcome data presents new challenges that are important to consider to improve our effective use of environmental health information. Our objective was to identify the common themes related to the integration of environmental and health data, and suggest ways to address the challenges and make progress toward more effective use of data already collected, to further our understanding of environmental health associations in the Great Lakes region. Environmental and human health databases were identified and reviewed using literature searches and a series of one-on-one and group expert consultations. Databases identified were predominantly environmental stressors databases, with fewer found for health outcomes and human exposure. Nine themes or factors that impact integration were identified: data availability, accessibility, harmonization, stakeholder collaboration, policy and strategic alignment, resource adequacy, environmental health indicators, and data exchange networks. The use and cost effectiveness of data currently collected could be improved by strategic changes to data collection and access systems to provide better opportunities to identify and study environmental exposures that may impact human health.

  5. Mind the Gap. A systematic review to identify usability and safety challenges and practices during electronic health record implementation.

    Science.gov (United States)

    Ratwani, Raj; Fairbanks, Terry; Savage, Erica; Adams, Katie; Wittie, Michael; Boone, Edna; Hayden, Andrew; Barnes, Janey; Hettinger, Zach; Gettinger, Andrew

    2016-11-16

    Decisions made during electronic health record (EHR) implementations profoundly affect usability and safety. This study aims to identify gaps between the current literature and key stakeholders' perceptions of usability and safety practices and the challenges encountered during the implementation of EHRs. Two approaches were used: a literature review and interviews with key stakeholders. We performed a systematic review of the literature to identify usability and safety challenges and best practices during implementation. A total of 55 articles were reviewed through searches of PubMed, Web of Science and Scopus. We used a qualitative approach to identify key stakeholders' perceptions; semi-structured interviews were conducted with a diverse set of health IT stakeholders to understand their current practices and challenges related to usability during implementation. We used a grounded theory approach: data were coded, sorted, and emerging themes were identified. Conclusions from both sources of data were compared to identify areas of misalignment. We identified six emerging themes from the literature and stakeholder interviews: cost and resources, risk assessment, governance and consensus building, customization, clinical workflow and usability testing, and training. Across these themes, there were misalignments between the literature and stakeholder perspectives, indicating major gaps. Major gaps identified from each of six emerging themes are discussed as critical areas for future research, opportunities for new stakeholder initiatives, and opportunities to better disseminate resources to improve the implementation of EHRs. Our analysis identified practices and challenges across six different emerging themes, illustrated important gaps, and results suggest critical areas for future research and dissemination to improve EHR implementation.

  6. An open dialogue on the draft focus and themes for the next ITS strategic research plan : engaging stakeholders in their discussion and development.

    Science.gov (United States)

    2012-12-01

    The : purpose : of : this : document : is : to : identify : the : focus : and : themes : for : the : next : installment : of : the : ITS : Strategic : Research : Plan : and : to : invite : stakeholders : to : participate : in : their : discussion. : ...

  7. The place of the clock in pediatric advice: rationales, cultural themes, and impediments to breastfeeding.

    Science.gov (United States)

    Millard, A V

    1990-01-01

    This analysis treats the U.S. medical literature as evidence concerning the formal system of knowledge in allopathic medicine. An examination of pediatric advice on breastfeeding reveals the logic of medical reasoning, the use of scientific rationales, and the intrusion of specific cultural themes. The corpus of data includes works of 18 authors published in 36 volumes from 1897 to 1987, 27 volumes being editions of two major pediatric textbooks. All sources advocate breastfeeding but the detailed advice on how to carry out the process actually tends to undermine it. Moreover, the clock has provided the main frame of reference, creating regimentation reminiscent of factory work, segmenting breastfeeding into a series of steps, and emphasizing efficiency in time and motion. Feeding schedules were advocated in former decades as a matter of discipline for the infant, but nowadays they are viewed as biologically innate to normal infants and to breast milk production. The literature manifests responses over the century to behavioral, biochemical and physiological studies; however, except possibly for one textbook, no thorough rethinking has occurred. Sources of the 1980s continue to focus on the tempo of feeding as a major concern. Cultural themes besides the factory model of breastfeeding include the extension of professional advice to family matters, the subordination of lay women to professional expertise, mistrust of women's bodily signals including the let-down reflex in determining the timing of feedings, mistrust of signals from infants as well, and a professional ideal of flexible advice coupled with rigid limits concerning schedules. The literature interweaves the cultural themes with rationales based on physiological studies in support of specific regimens in breastfeeding, and the relegation of control in breastfeeding to medical experts denies the validity of mutual bodily and emotional responses within the mother-infant dyad. Pediatric authorities thus

  8. Mapping of Themes Pertaining to Operations Management: a Refined Analysis Based on the Perceptions of Researchers, Lecturers and Practitioners

    Directory of Open Access Journals (Sweden)

    Jurandir Peinado

    2016-01-01

    Full Text Available An article published at Revista de Gestão (REGE, an academic journal by the University of Sao Paulo, in 2013, proposed the mapping of Operations Management themes based on the editorial space provided in major journals and conf erence proceedings in the area. Based on such proposal, the current study conducted a survey to capture the importance assigned to those themes by researchers, lecturers and practitioners and how they categorized the themes into broader groupings. A factor analysis was performed with the data collected by means of the survey and several statistical tests were also carried out in order to assess the strength of the constructs and to confirm the dimensions proposed in the referred mapping of Operations Manage ment themes, allowing for its refinement. The factor analysis resulted in nine factors, seven of which very closely resemble the constructs presented in the previous paper. Thus, the results obtained herein confirm most of the previously obtained mapping, providing a further step in the discussion of the themes that are relevant to the area of Operations Management

  9. The theme revenge in the cinema: a literary philosophical approach

    Directory of Open Access Journals (Sweden)

    Fábio José de Queiroz

    2016-04-01

    Full Text Available In this article, the focus is revenge, taking as a starting point two cinematographic works –Once upon a time in this article is revenge, taking as a starting point two cinematographic works­ once upon a time in West, by Sergio Leone, and also colors: White by Krzysztof Kieslowsk. Without the direct influence of a purely artistic appreciation of both movies, this is about a study of literary­ philosophical lineage by relying on classical seeks to provide an theoretical analyze of the theme, avoiding falling into an empiricist interpretation, trivial and shallow of the object.

  10. The beauty of simple models: Themes in recognition heuristic research

    Directory of Open Access Journals (Sweden)

    Daniel G. Goldstein

    2011-07-01

    Full Text Available The advantage of models that do not use flexible parameters is that one can precisely show to what degree they predict behavior, and in what situations. In three issues of this journal, the recognition heuristic has been examined carefully from many points of view. We comment here on four themes, the use of optimization models to understand the rationality of heuristics, the generalization of the recognition input beyond a binary judgment, new conditions for less-is-more effects, and the importance of specifying boundary conditions for cognitive heuristics.

  11. Assessment of the quality seen in a restaurant typical theme

    Directory of Open Access Journals (Sweden)

    Francisco Alves Pinheiro

    2009-03-01

    Full Text Available To ensure the satisfaction of external customers it is necessary to know their needs. In this perspective, these work objectives assess the perception of quality by the customer outside of a restaurant located in the a restaurant typical theme located in the square of food “Bodódromo” the city of Petrolina/Pe. For both this was a case study, using the model servqual, Parasuraman et al (1985, for removal of information. The results indicated a need for improvement in the services provided by the restaurant.

  12. [Suicide -- an essay trying to reveal the theme].

    Science.gov (United States)

    Sampaio, M A; Boemer, M R

    2000-12-01

    This essay proposes to reveal facets of the suicide through the discourse of different authors treating this theme as well as through contacts that I was able to have in my nursing training, through my academic trajectory. This trajectory includes an incursion by phenomenological ideas, mainly by the ideas of Heidegger and his existential analysis of the man as being-there. In this way, the understanding of a person who decides to finalize his/her existence, can be, by the existential analysis perspective, a way to reconstruct and redimension his/her existential perspectives.

  13. Emergent Themes from Recent Research Syntheses in Science Education and Their Implications for Research Design, Replication, and Reporting Practices

    Science.gov (United States)

    Taylor, Joseph; Furtak, Erin; Kowalski, Susan; Martinez, Alina; Slavin, Robert; Stuhlsatz, Molly; Wilson, Christopher

    2016-01-01

    This article draws upon the experiences of four recent efforts to synthesize the findings of quantitative studies in science education research. After establishing the need for research syntheses in advancing generalizable knowledge and causal effects research in our field, we identify a set themes that emerged in the process of conducting these…

  14. Chaotic Careers: A Narrative Analysis of Career Transition Themes and Outcomes Using Chaos Theory as a Guiding Metaphor

    Science.gov (United States)

    Peake, Sharon; McDowall, Almuth

    2012-01-01

    In a rapidly changing world of work, little research exists on mid-career transitions. We investigated these using the open-systems approach of chaos theory as a guiding metaphor and conducted interviews with seven mid-career individuals chosen for their experience of a significant mid-career transition. Four common themes were identified through…

  15. African-American students' perceptions of their majors, future professions, and the dietetics major and profession: a qualitative analysis.

    Science.gov (United States)

    Felton, Teena M; Nickols-Richardson, Sharon M; Serrano, Elena; Hosig, Kathy W

    2008-07-01

    African-American professionals are underrepresented in the profession of dietetics. This preliminary qualitative study identified African-American students' perceptions of their majors, future professions, and the dietetics major/profession to understand why they did or did not enter dietetics. It was hypothesized that dietetics students chose dietetics primarily for altruistic reasons, whereas students in other fields of study did not choose dietetics due to lack of awareness of dietetics. To learn students' views, African-American college students engaged in elicitation interviews or focus group discussions. Twenty-eight women and 12 men participated. Phenomenologic analysis identified common themes and meanings: African-American students selected their majors for a variety of reasons, including desire to help people, interest in the field, recommendation from an adult, and family influence. African-American students in fields of study other than dietetics believed that the dietetics major was not selected due to lack of awareness about dietetics. Both dietetics students and students in other fields of study perceived versatility, ability to work with/help people, and to have an influence as positive qualities about their future professions. Advanced degree and training requirements, lack of diversity, and low salary were identified as negative qualities about future professions. African-American students in fields of study other than dietetics had not been exposed to the dietetics major, careers, and profession. Recruitment efforts should begin early to increase the number of African-American students in dietetics.

  16. Living in imaginary places: on the creation and consumption of themed residential architecture

    OpenAIRE

    Meier, S.O.

    2013-01-01

    This study deals with theming of residential space and architecture. In theoretical terms, theming is defined as the application of a narrative to places and the built environment to make them more appealing than they otherwise would be. In a broader sense it is argued that theming is related to an intensified commodification of places through which, in turn, the number of hyperspaces has been increased. While theming primarily has been applied to restaurants, shopping malls or theme parks, t...

  17. Quality of life themes in Canadian adults and street youth who are homeless or hard-to-house: a multi-site focus group study.

    Science.gov (United States)

    Palepu, Anita; Hubley, Anita M; Russell, Lara B; Gadermann, Anne M; Chinni, Mary

    2012-08-15

    The aim of this study was to identify what is most important to the quality of life (QoL) of those who experience homelessness by directly soliciting the views of homeless and hard-to-house Canadians themselves. These individuals live within a unique social context that differs considerably from that of the general population. To understand the life areas that are most important to them, it is critical to have direct input from target populations of homeless and hard-to-house persons. Focus groups were conducted with 140 individuals aged 15 to 73 years who were homeless or hard-to-house to explore the circumstances in which they were living and to capture what they find to be important and relevant domains of QoL. Participants were recruited in Toronto, Ottawa, Montreal, and Vancouver. Content analysis was used to analyze the data. Six major content themes emerged: Health/health care; Living conditions; Financial situation; Employment situation; Relationships; and Recreational and leisure activities. These themes were linked to broader concepts that included having choices, stability, respect, and the same rights as other members of society. These findings not only aid our understanding of QoL in this group, but may be used to develop measures that capture QoL in this population and help programs and policies become more effective in improving the life situation for persons who are homeless and hard-to-house. Quality of life themes in Canadian adults and street youth who are homeless or hard-to-house: A multi-site focus group study.

  18. Quality of life themes in Canadian adults and street youth who are homeless or hard-to-house: A multi-site focus group study

    Directory of Open Access Journals (Sweden)

    Palepu Anita

    2012-08-01

    Full Text Available Abstract Background The aim of this study was to identify what is most important to the quality of life (QoL of those who experience homelessness by directly soliciting the views of homeless and hard-to-house Canadians themselves. These individuals live within a unique social context that differs considerably from that of the general population. To understand the life areas that are most important to them, it is critical to have direct input from target populations of homeless and hard-to-house persons. Methods Focus groups were conducted with 140 individuals aged 15 to 73 years who were homeless or hard-to-house to explore the circumstances in which they were living and to capture what they find to be important and relevant domains of QoL. Participants were recruited in Toronto, Ottawa, Montreal, and Vancouver. Content analysis was used to analyze the data. Results Six major content themes emerged: Health/health care; Living conditions; Financial situation; Employment situation; Relationships; and Recreational and leisure activities. These themes were linked to broader concepts that included having choices, stability, respect, and the same rights as other members of society. Conclusions These findings not only aid our understanding of QoL in this group, but may be used to develop measures that capture QoL in this population and help programs and policies become more effective in improving the life situation for persons who are homeless and hard-to-house. Quality of life themes in Canadian adults and street youth who are homeless or hard-to-house: A multi-site focus group study.

  19. Introduction to the Theme "New Methods and Novel Therapeutic Approaches in Pharmacology and Toxicology".

    Science.gov (United States)

    Insel, Paul A; Amara, Susan G; Blaschke, Terrence F; Meyer, Urs A

    2017-01-06

    Major advances in scientific discovery and insights can result from the development and use of new techniques, as exemplified by the work of Solomon Snyder, who writes a prefatory article in this volume. The Editors have chosen "New Methods and Novel Therapeutic Approaches in Pharmacology and Toxicology" as the Theme for a number of articles in this volume. These include ones that review the development and use of new experimental tools and approaches (e.g., nanobodies and techniques to explore protein-protein interactions), new types of therapeutics (e.g., aptamers and antisense oligonucleotides), and systems pharmacology, which assembles (big) data derived from omics studies together with information regarding drugs and patients. The application of these new methods and therapeutic approaches has the potential to have a major impact on basic and clinical research in pharmacology and toxicology as well as on patient care.

  20. The expression of depression among Javanese patients with major depressive disorder: a concept mapping study.

    Science.gov (United States)

    Brintnell, E Sharon; Sommer, Ryan W; Kuncoro, Bambang; Setiawan, G Pandu; Bailey, Patricia

    2013-08-01

    In this study, we explored the presentation of clinical depression in Java, Indonesia. Interviews were conducted with 20 Javanese patients (male and female) with major depressive disorder from both lower and higher socioeconomic levels. The recruited participants came from provincial and private mental health hospitals in the cities of Solo, Yogykarta (Jogja), Jakarta, and Malang on the island of Java, Indonesia. Concept mapping methodology using multidimensional scaling and hierarchical cluster analysis was used to identify underlying themes in the expression of depressive phenomena in this Indonesian population. The results identified themes that grouped into six clusters: interpersonal relationships, hopelessness, physical/somatic, poverty of thought, discourage, and defeat. Findings give support to the view that culture influences the expression of Indonesian depressive phenomenology, which nevertheless has some common roots with Western clinical pictures of the disorder. Cultural influences may mask symptoms of the disorder to clinicians. Diagnostic and assessment tools must be carefully selected to ensure they address culturally specific expressions of depression.

  1. A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “ARE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance*

    Science.gov (United States)

    Ruggles, Kelly V.; Garbarino, Jeanne; Liu, Ying; Moon, James; Schneider, Kerry; Henneberry, Annette; Billheimer, Jeff; Millar, John S.; Marchadier, Dawn; Valasek, Mark A.; Joblin-Mills, Aidan; Gulati, Sonia; Munkacsi, Andrew B.; Repa, Joyce J.; Rader, Dan; Sturley, Stephen L.

    2014-01-01

    The toxic subcellular accumulation of lipids predisposes several human metabolic syndromes, including obesity, type 2 diabetes, and some forms of neurodegeneration. To identify pathways that prevent lipid-induced cell death, we performed a genome-wide fatty acid sensitivity screen in Saccharomyces cerevisiae. We identified 167 yeast mutants as sensitive to 0.5 mm palmitoleate, 45% of which define pathways that were conserved in humans. 63 lesions also impacted the status of the lipid droplet; however, this was not correlated to the degree of fatty acid sensitivity. The most liposensitive yeast strain arose due to deletion of the “ARE2 required for viability” (ARV1) gene, encoding an evolutionarily conserved, potential lipid transporter that localizes to the endoplasmic reticulum membrane. Down-regulation of mammalian ARV1 in MIN6 pancreatic β-cells or HEK293 cells resulted in decreased neutral lipid synthesis, increased fatty acid sensitivity, and lipoapoptosis. Conversely, elevated expression of human ARV1 in HEK293 cells or mouse liver significantly increased triglyceride mass and lipid droplet number. The ARV1-induced hepatic triglyceride accumulation was accompanied by up-regulation of DGAT1, a triglyceride synthesis gene, and the fatty acid transporter, CD36. Furthermore, ARV1 was identified as a transcriptional of the protein peroxisome proliferator-activated receptor α (PPARα), a key regulator of lipid homeostasis whose transcriptional targets include DGAT1 and CD36. These results implicate ARV1 as a protective factor in lipotoxic diseases due to modulation of fatty acid metabolism. In conclusion, a lipotoxicity-based genetic screen in a model microorganism has identified 75 human genes that may play key roles in neutral lipid metabolism and disease. PMID:24273168

  2. A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance.

    Science.gov (United States)

    Ruggles, Kelly V; Garbarino, Jeanne; Liu, Ying; Moon, James; Schneider, Kerry; Henneberry, Annette; Billheimer, Jeff; Millar, John S; Marchadier, Dawn; Valasek, Mark A; Joblin-Mills, Aidan; Gulati, Sonia; Munkacsi, Andrew B; Repa, Joyce J; Rader, Dan; Sturley, Stephen L

    2014-02-14

    The toxic subcellular accumulation of lipids predisposes several human metabolic syndromes, including obesity, type 2 diabetes, and some forms of neurodegeneration. To identify pathways that prevent lipid-induced cell death, we performed a genome-wide fatty acid sensitivity screen in Saccharomyces cerevisiae. We identified 167 yeast mutants as sensitive to 0.5 mm palmitoleate, 45% of which define pathways that were conserved in humans. 63 lesions also impacted the status of the lipid droplet; however, this was not correlated to the degree of fatty acid sensitivity. The most liposensitive yeast strain arose due to deletion of the "ARE2 required for viability" (ARV1) gene, encoding an evolutionarily conserved, potential lipid transporter that localizes to the endoplasmic reticulum membrane. Down-regulation of mammalian ARV1 in MIN6 pancreatic β-cells or HEK293 cells resulted in decreased neutral lipid synthesis, increased fatty acid sensitivity, and lipoapoptosis. Conversely, elevated expression of human ARV1 in HEK293 cells or mouse liver significantly increased triglyceride mass and lipid droplet number. The ARV1-induced hepatic triglyceride accumulation was accompanied by up-regulation of DGAT1, a triglyceride synthesis gene, and the fatty acid transporter, CD36. Furthermore, ARV1 was identified as a transcriptional of the protein peroxisome proliferator-activated receptor α (PPARα), a key regulator of lipid homeostasis whose transcriptional targets include DGAT1 and CD36. These results implicate ARV1 as a protective factor in lipotoxic diseases due to modulation of fatty acid metabolism. In conclusion, a lipotoxicity-based genetic screen in a model microorganism has identified 75 human genes that may play key roles in neutral lipid metabolism and disease.

  3. Some Themes in the Discussion of the Quality of Life

    DEFF Research Database (Denmark)

    Røpke, Inge

    1999-01-01

    Abstract This paper is motivated by the need to discuss the quality of life as a part of the background for devising environmental strategies. When environmental strategies are devised, it is often more or less tacitly assumed that we should try to avoid measures that imply a decrease in the level....... The critical perspective is developed by dealing with welfare or the quality of life: what does it mean to have a good life? On the basis of this discussion, the relationship between consumption and welfare can then be assessed. The approach to the discussion of the quality of life in this paper is first...... with the different themes in the discussion of the quality of life. The point of departure is taken in some critical considerations related to the traditional conceptualization of welfare. After that, some inspiration from the debate on basic needs is outlined and supplemented with some reflections on the dual...

  4. Communication and Health - themes, issues and Latin American perspectives

    OpenAIRE

    Araujo, Inesita Soares de; Cabrera, Jesús Arroyave

    2012-01-01

    Editorial Reciis Vol 6, No. 4 -. Communication and Health - themes, issues and Latin American perspectives Editorial Vol Reciis 6, No. 4 -. De Comunicación y Salud - temas, problemas y perspectivas de América Latina A Comunicação e Saúde vem conhecendo nas duas últimas décadas uma grande expansão. Formada na interface de dois campos solidamente constituídos – o da Comunicação e o da Saúde – e frequentemente articulada com os da Ciência &Tecnologia e da Educação, a Comunicação e Saúd...

  5. Discussing agrochemical themes: an approach through socio-scientific controversies

    Directory of Open Access Journals (Sweden)

    Eril Medeiros da Fonseca

    2017-12-01

    Full Text Available The theme of "agro-toxicology" in the Rural Education pervades key issues to be problematized, such as the care of rural workers, from the concept of health as something broad, involving access to cultural goods, leisure and communication and still, the collective physical, mental and social well-being. The use of pesticides, in addition to compromising the health of those who work in the field and those who feed on what is produced in the field, brings with it a conception of health that, in addition to suffering and individualizing, affects our biological diversity. The objective of this study is to discuss pesticides and their implications for health, through the approach of Socio-Scientific Controversies (CSC in Science Teaching and Rural Education.

  6. Biblical and liturgical themes in Krzysztof Penderecki’s activity

    Directory of Open Access Journals (Sweden)

    Janusz Drewniak

    2007-06-01

    Full Text Available Krzysztof Penderecki (born 1933 is considered to be one of the most outstanding contemporary composers. The religious theme is often taken to be an inspiration for his vocal-instrumental output. Penderecki presents in his compositions the religious and moral problems related to the human nature and existence. The principal issues in his activity are a trial to find a reason of evil and misfortune and also the vision of ordeal. The composer makes use of not only biblical and liturgical texts but also religious poetry mainly in latin language. His religious output has a concert character thanks to the musician language and composing techniques. His own commentaries concerning his compositions prove that his religious activity is an artistic confession of his faith.

  7. THE EGIPTIAN THEME IN THE WORK OF A. P. CHEKHOV

    Directory of Open Access Journals (Sweden)

    Elena L. Suzryukova

    2017-06-01

    Full Text Available The present article deals with the biblical themes of the escape to Egypt and the exodus from Egypt as depicted in the narrative and the epistolary fiction of the writer. In the letters of A. P. Chekhov Egypt is associated with favorable living conditions for those who suffer from lung diseases. Besides, the author was taken with the idea of visiting this country, but his dream did not come true. In the early Anton Chekhov’s short story “Holiday” [“Prazdnichnye”] the motif of the escape to Egypt is put in a humorous context. The same motif along with the motif of the Exodus from Egypt was used by the author in the story “Men” [“Muzhiki”]. Both in the letters and in the stories and novels of the writer, the motif of the escape to Egypt keeps the Christian semantics of Salvation. In the short story “Misery” [“Toska”] Egypt is implicitly present — it is linked with the epigraph to the text, the basis for which is a spiritual verse “Weeping of Joseph, when his brothers sold him in Egypt”. The motif of being in Egyptian slavery — another aspect of the theme in question — translates into a number of works and letters of A. P. Chekhov. This motif is associated with the meanings of freedom and grief. The article reveals and analyses the antinomic images of St. Mary of Egypt and Cleopatra of Egypt. Besides, it explores semantic realization of the set expression “plague of Egypt”.

  8. Primary mental health prevention themes in published research and academic programs in Israel.

    Science.gov (United States)

    Nakash, Ora; Razon, Liat; Levav, Itzhak

    2015-01-01

    The World Health Organization Comprehensive Mental Health Action Plan (CMHAP) 2013-2020 proposes the implementation of primary prevention strategies to reduce the mental health burden of disease. The extent to which Israeli academic programs and published research adhere to the principles spelled out by the CMHAP is unknown. To investigate the presence of mental health primary prevention themes in published research and academic programs in Israel. We searched for mental health primary prevention themes in: (1) three major journals of psychiatry and social sciences during the years 2001-2012; (2) university graduate programs in psychology, social work and medicine in leading universities for the academic year of 2011-2012; and (3) doctoral and master's theses approved in psychology and social work departments in five universities between the years 2007-2012. We used a liberal definition of primary prevention to guide the above identification of themes, including those related to theory, methods or research information of direct or indirect application in practice. Of the 934 articles published in the three journals, 7.2%, n = 67, addressed primary prevention. Of the 899 courses in the 19 graduate programs 5.2%, n = 47, elective courses addressed primary prevention. Of the 1960 approved doctoral and master's theses 6.2%, n = 123, addressed primary prevention. Only 11 (4.7%) articles, 5 (0.6%) courses, and 5 (0.3%) doctoral and master's theses addressed primary prevention directly. The psychiatric reform currently implemented in Israel and WHO CMHAP call for novel policies and course of action in all levels of prevention, including primary prevention. Yet, the latter is rarely a component of mental health education and research activities. The baseline we drew could serve to evaluate future progress in the field.

  9. A review of obesity-themed policy briefs.

    Science.gov (United States)

    Dodson, Elizabeth A; Eyler, Amy A; Chalifour, Stephanie; Wintrode, Christopher G

    2012-09-01

    Policy approaches are one of the most promising population-based means of addressing the epidemic of obesity in the U.S., especially as they create supportive environments for healthy living. Policy briefs can be an effective means of disseminating research information to inform obesity prevention efforts; however, they are often ineffective because of length, density, and inaccessibility. The purposes of this project were to identify a collection of obesity-related policy briefs, analyze the content, and make recommendations for model policy briefs. In 2010, online searching strategies were developed with criteria that included a primary topical focus on obesity, written between 2000 and 2010, targeting any population age group, including a policy-change message, and being readily available online. The research team developed a coding tool and used it to analyze briefs. A subsample of the briefs was used for further analysis on dissemination. Analyses were conducted on 100 briefs. Most (72%) were developed between 2005 and 2010; the average length was five pages. The majority had no tables, few figures, and only 36% included photos. The average reading level was high. A lack of monitoring or evaluating dissemination efforts prevailed. Policy briefs represent an effective, often-preferred, potent tool for public health practitioners and researchers to communicate information to policymakers. Recommendations include presenting information clearly, using a concise format, including design elements, noting reference and contact information, employing active and targeted dissemination efforts, and conducting evaluation. Copyright © 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Adults Contemplating University Study at a Distance: Issues, themes and concerns

    Directory of Open Access Journals (Sweden)

    Chris Morgan

    2003-04-01

    Full Text Available This study identifies and explores a range of themes, issues and questions that commonly confront adults contemplating enrolment in university, and why they persist. The study focuses particularly on issues facing prospective adult distance education learners. From a range of interviews, six themes were identified including fears, motivation, support from home, academic preparedness, suitability of programs, and identity change.It is argued that the more effective we become at information provision, guidance and preparation of adult pre-entry open and distance learners, the more likely students will experience a smooth transition to study, thus improving both student satisfaction and retention rates. Successful intervention with prospective distance education learners at this early point should aim to assist the process of informed decision making, which could result equally in an individual deciding not to pursue university study. The findings in this study should be particularly useful for those academics, course advisors, student counsellors, teachers in preparatory programs, and university information and support officers, and others who provide adult distance students, with pre-enrolment information and advice.

  11. EMSL Geochemistry, Biogeochemistry and Subsurface Science-Science Theme Advisory Panel Meeting

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Gordon E.; Chaka, Anne; Shuh, David K.; Roden, Eric E.; Werth, Charles J.; Hess, Nancy J.; Felmy, Andrew R.; Rosso, Kevin M.; Baer, Donald R.; Bailey, Vanessa L.; Bowden, Mark E.; Grate, Jay W.; Hoyt, David W.; Kuprat, Laura R.; Lea, Alan S.; Mueller, Karl T.; Oostrom, Martinus; Orr, Galya; Pasa-Tolic, Ljiljana; Plata, Charity; Robinson, E. W.; Teller, Raymond G.; Thevuthasan, Suntharampillai; Wang, Hongfei; Wiley, H. S.; Wilkins, Michael J.

    2011-08-01

    This report covers the topics of discussion and the recommendations of the panel members. On December 8 and 9, 2010, the Geochemistry, Biogeochemistry, and Subsurface Science (GBSS) Science Theme Advisory Panel (STAP) convened for a more in-depth exploration of the five Science Theme focus areas developed at a similar meeting held in 2009. The goal for the fiscal year (FY) 2011 meeting was to identify potential topical areas for science campaigns, necessary experimental development needs, and scientific members for potential research teams. After a review of the current science in each of the five focus areas, the 2010 STAP discussions successfully led to the identification of one well focused campaign idea in pore-scale modeling and five longer-term potential research campaign ideas that would likely require additional workshops to identify specific research thrusts. These five campaign areas can be grouped into two categories: (1) the application of advanced high-resolution, high mass accuracy experimental techniques to elucidate the interplay between geochemistry and microbial communities in terrestrial ecosystems and (2) coupled computation/experimental investigations of the electron transfer reactions either between mineral surfaces and outer membranes of microbial cells or between the outer and inner membranes of microbial cells.

  12. Network methods to support user involvement in qualitative data analyses: an introduction to Participatory Theme Elicitation.

    Science.gov (United States)

    Best, Paul; Badham, Jennifer; Corepal, Rekesh; O'Neill, Roisin F; Tully, Mark A; Kee, Frank; Hunter, Ruth F

    2017-11-23

    While Patient and Public Involvement (PPI) is encouraged throughout the research process, engagement is typically limited to intervention design and post-analysis stages. There are few approaches to participatory data analyses within complex health interventions. Using qualitative data from a feasibility randomised controlled trial (RCT), this proof-of-concept study tests the value of a new approach to participatory data analysis called Participatory Theme Elicitation (PTE). Forty excerpts were given to eight members of a youth advisory PPI panel to sort into piles based on their perception of related thematic content. Using algorithms to detect communities in networks, excerpts were then assigned to a thematic cluster that combined the panel members' perspectives. Network analysis techniques were also used to identify key excerpts in each grouping that were then further explored qualitatively. While PTE analysis was, for the most part, consistent with the researcher-led analysis, young people also identified new emerging thematic content. PTE appears promising for encouraging user led identification of themes arising from qualitative data collected during complex interventions. Further work is required to validate and extend this method. ClinicalTrials.gov, ID: NCT02455986 . Retrospectively Registered on 21 May 2015.

  13. Integrated Network Analysis Identifies Fight-Club Nodes as a Class of Hubs Encompassing Key Putative Switch Genes That Induce Major Transcriptome Reprogramming during Grapevine Development[W][OPEN

    Science.gov (United States)

    Palumbo, Maria Concetta; Zenoni, Sara; Fasoli, Marianna; Massonnet, Mélanie; Farina, Lorenzo; Castiglione, Filippo; Pezzotti, Mario; Paci, Paola

    2014-01-01

    We developed an approach that integrates different network-based methods to analyze the correlation network arising from large-scale gene expression data. By studying grapevine (Vitis vinifera) and tomato (Solanum lycopersicum) gene expression atlases and a grapevine berry transcriptomic data set during the transition from immature to mature growth, we identified a category named “fight-club hubs” characterized by a marked negative correlation with the expression profiles of neighboring genes in the network. A special subset named “switch genes” was identified, with the additional property of many significant negative correlations outside their own group in the network. Switch genes are involved in multiple processes and include transcription factors that may be considered master regulators of the previously reported transcriptome remodeling that marks the developmental shift from immature to mature growth. All switch genes, expressed at low levels in vegetative/green tissues, showed a significant increase in mature/woody organs, suggesting a potential regulatory role during the developmental transition. Finally, our analysis of tomato gene expression data sets showed that wild-type switch genes are downregulated in ripening-deficient mutants. The identification of known master regulators of tomato fruit maturation suggests our method is suitable for the detection of key regulators of organ development in different fleshy fruit crops. PMID:25490918

  14. Emotional hyper-reactivity in borderline personality disorder is related to trauma and interpersonal themes.

    Science.gov (United States)

    Sauer, Christina; Arens, Elisabeth A; Stopsack, Malte; Spitzer, Carsten; Barnow, Sven

    2014-12-15

    Heightened emotional reactivity is one of the core features of borderline personality disorder (BPD). However, recent findings could not provide evidence for a general emotional hyper-reactivity in BPD. The present study examines the emotional responding to self-relevant pictures in dependency of the thematic category (e.g., trauma, interpersonal interaction) in patients with BPD. Therefore, women with BPD (n=31), women with major depression disorder (n=29) and female healthy controls (n=33) rated pictures allocated to thematically different categories (violence, sexual abuse, interaction, non-suicidal self-injury, and suicide) regarding self-relevance, arousal, valence and the urge of non-suicidal self-injury. Compared to both control groups, patients with BPD reported higher self-relevance regarding all categories, but significantly higher emotional ratings only for pictures showing sexual abuse and interpersonal themes. In addition, patients with BPD and comorbid posttraumatic stress disorder showed higher emotional reactivity in violence pictures. Our data provide clear evidence that patients with BPD show a specific emotional hyper-reactivity with respect to schema-related triggers like trauma and interpersonal situations. Future studies are needed to investigate physiological responses to these self-relevant themes in patients with BPD. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  15. Four themes that underlie the high-level nuclear waste management program

    International Nuclear Information System (INIS)

    Sprecher, W.M.

    1989-01-01

    In 1982, after years of deliberation and in response to mounting pressures from environmental, industrial, and other groups, the US Congress enacted the Nuclear Waste Policy Act (NWPA) of 1982, which was signed into law by the President in January 1983. That legislation signified a major milestone in the nation's management of high-level nuclear waste, since it represented a consensus among the nation's lawmakers to tackle a problem that had evaded solution for decades. Implementation of the NWPA has proven to be exceedingly difficult, as attested by the discord generated by the US Department of Energy's (DOE's) geologic repository and monitored retrievable storage (MRS) facility siting activities. The vision that motivated the crafters of the 1982 act became blurred as opposition to the law increased. After many hearings that underscored the public's concern with the waste management program, the Congress enacted the Nuclear Waste Policy Amendments Act of 1987 (Amendments Act), which steamlined and focused the program, while establishing three independent bodies: the MRS Review Commission, the Nuclear Waste Technical Review Board, and the Office of the Nuclear Waste Negotiator. Yet, even as the program evolves, several themes characterizing the nation's effort to solve the waste management problem continue to prevail. The first of these themes has to do with social consciousness, and the others that follow deal with technical leadership, public involvement and risk perceptions, and program conservatism

  16. Modelling the migration and accumulation of radionuclides in forest ecosystems. Report of the Forest Working Group of BIOMASS Theme 3

    International Nuclear Information System (INIS)

    2002-08-01

    The IAEA Programme on BIOsphere Modelling and ASSessment (BIOMASS) was launched in Vienna in October 1996. The programme was concerned with developing and improving capabilities to predict the transfer of radionuclides in the environment. The programme had three themes: Theme 1: Radioactive Waste Disposal. The objective was to develop the concept of a standard or reference biosphere for application to the assessment of the long-term safety of repositories for radioactive waste. Under the general heading of 'Reference Biospheres', six Task Groups were established: Task Group 1: Principles for the Definition of Critical and Other Exposure Groups. Task Group 2: Principles for the Application of Data to Assessment Models. Task Group 3: Consideration of Alternative Assessment Contexts. Task Group 4: Biosphere System Identification and Justification. Task Group 5: Biosphere System Descriptions. Task Group 6: Model Development. Theme 2: Environmental Releases. BIOMASS provided an international forum for activities aimed at increasing the confidence in methods and models for the assessment of radiation exposure related to environmental releases. Two Working Groups addressed issues concerned with the reconstruction of radiation doses received by people from past releases of radionuclides to the environment and the evaluation of the efficacy of remedial measures. Theme 3: Biosphere Processes. The aim of this Theme was to improve capabilities for modelling the transfer of radionuclides in particular parts of the biosphere identified as being of potential radiological significance and where there were gaps in modelling approaches. This topic was explored using a range of methods including reviews of the literature, model inter-comparison exercises and, where possible, model testing against independent sources of data. Three Working Groups were established to examine the modelling of: (1) long-term tritium dispersion in the environment; (2) radionuclide uptake by fruits; and (3

  17. Exploring the practical themes for medical education social accountability in Iran.

    Science.gov (United States)

    Ahmady, Soleiman; Akbari Lakeh, Maryam

    2015-01-01

    The purpose of this paper is to explore themes for enhancing socially accountability in medical education. Medical education in Iran experience new challenges due to the enormous influence of changes in technology, development of new methods of teaching and learning, student requirements, patient management, financial credit constraints, and social and economic developments. For responding to these, use of strategic thinking in order to make appropriate decisions is the only solution. Strategic plans need to formulate practical guides which can help accountable to people's reasonable expectations. For this qualitative study, along with the 14(th)national conference on Medical Education in Iran, the opinions of experts were obtained during seven expert panels' group discussions, each lasting four hours and including 10 participants. Data were collected by audiotapes, which were then transcribed. Data analyzed using a thematic content analysis approach. Peer and member checking during analysis and data triangulation from other recent studies were used to increase the findings' trustworthiness. Among more than hundred meaning units groups identified the following eight main themes as affecting the social accountable medical education in Iran: organization of responsive education councils; development of community based courses; development in field training; organization of educational processes; homogeneity in educational rules and regulations; budget management, educational outcomes; educational programs in departments and groups. This study have found the main themes that might affecting social accountable medical education in Iran, where Iranian policymakers should consider those when plan to make changes in medical education and could potentially adopt the proven useful policies and strategies of other countries.

  18. Workforce Skills and Innovation: An Overview of Major Themes in the Literature. OECD Education Working Papers, No. 55

    Science.gov (United States)

    Toner, Phillip

    2011-01-01

    This paper provides an account of the main approaches, debates and evidence in the literature on the role of workforce skills in the innovation process in developed economies. It draws on multiple sources including the innovation studies discipline, neoclassical Human Capital theory, institutionalist labour market studies and the work organisation…

  19. Aberrant Free Radical Biology Is a Unifying Theme in the Etiology and Pathogenesis of Major Human Diseases

    Directory of Open Access Journals (Sweden)

    Frederick E. Domann

    2013-04-01

    Full Text Available The seemingly disparate areas of oxygen toxicity, radiation exposure, and aging are now recognized to share a common feature—the aberrant production and/or removal of biologically derived free radicals and other reactive oxygen and nitrogen species (ROS/RNS. Advances in our understanding of the effects of free radicals in biology and medicine have been, and continue to be, actively translated into clinically tractable diagnostic and therapeutic applications. This issue is dedicated to recent advances, both basic discoveries and clinical applications, in the field of free radicals in biology and medicine. As more is understood about the proximal biological targets of aberrantly produced or removed reactive species, their sensors, and effectors of compensatory response, a great deal more will be learned about the commonalities in mechanisms underlying seemingly disparate disease states. Together with this deeper understanding, opportunities will arise to devise rational therapeutic interventions to decrease the incidence and severity of these diseases and positively impact the human healthspan.

  20. Foreword to the theme issue on geospatial computer vision

    Science.gov (United States)

    Wegner, Jan Dirk; Tuia, Devis; Yang, Michael; Mallet, Clement

    2018-06-01

    Geospatial Computer Vision has become one of the most prevalent emerging fields of investigation in Earth Observation in the last few years. In this theme issue, we aim at showcasing a number of works at the interface between remote sensing, photogrammetry, image processing, computer vision and machine learning. In light of recent sensor developments - both from the ground as from above - an unprecedented (and ever growing) quantity of geospatial data is available for tackling challenging and urgent tasks such as environmental monitoring (deforestation, carbon sequestration, climate change mitigation), disaster management, autonomous driving or the monitoring of conflicts. The new bottleneck for serving these applications is the extraction of relevant information from such large amounts of multimodal data. This includes sources, stemming from multiple sensors, that exhibit distinct physical nature of heterogeneous quality, spatial, spectral and temporal resolutions. They are as diverse as multi-/hyperspectral satellite sensors, color cameras on drones, laser scanning devices, existing open land-cover geodatabases and social media. Such core data processing is mandatory so as to generate semantic land-cover maps, accurate detection and trajectories of objects of interest, as well as by-products of superior added-value: georeferenced data, images with enhanced geometric and radiometric qualities, or Digital Surface and Elevation Models.

  1. Theme day: corrosion and surface treatments in nuclear facilities. Proceedings

    International Nuclear Information System (INIS)

    2012-02-01

    This document brings together the available presentations given at the theme day organized by the Bourgogne Nuclear Pole on the topic of corrosion and surface treatments in nuclear facilities. Eleven presentations (slides) are compiled in this document: 1 - Introduction - PNB centre of competitiveness and R and D activities (A. Mantovan, PNB); 2 - Corrosion damage (M. Foucault, Areva NP - Centre Technique Le Creusot); 3 - Corrosion mechanisms (R. Oltra, UB-ICB); 4 - Examples of expertise management (C. Duret-Thual, Institut de la corrosion/Corrosion Institute); 5 - General framework of surface treatments (C. Nouveau, ENSAM Cluny Paris Tech); 6 - Surfaces et interfaces characterisation - Part A (C. Langlade, Y. Gachon, UTBM and HEF); 7 - Surfaces et interfaces characterisation - Part B (C. Langlade, Y. Gachon, UTBM and HEF); 8 - Ion beam surface treatment (Y. Le Guellec, Quertech Ingenierie); 9 - Impact surface treatment (G. Saout, Sonats); 10 - Metal oxides Characterisation by US laser (R. Oltra, UB-ICB); 11 - Detection and Characterisation of intergranular corrosion (Y. Kernin, Stephane Bourgois, Areva Intercontrole)

  2. Recreating Jane: “Austenland” and the Regency Theme Park

    Directory of Open Access Journals (Sweden)

    Maddalena Pennacchia

    2017-12-01

    Full Text Available In the maze of Austen’s ever-expanding textuality – with its prequels, sequels, rewritings and adaptations – it may be worth paying attention to an unpretentious little book by Shannon Hale titled Austenland (2007. The story is about the adventures of a New Yorker thirty-something with a name that says it all: Jane. Being obsessed with Mr Darcy as played by Colin Firth, she decides to be healed by her excessive Austenian fantasies (or rather to indulge in them for the last time by spending all her savings on a English Regency Theme park that promises to offer Janeites a real full immersive Austen experience. What interests me in this post-Austenian story is the embedded discourse of leisure and tourism in the age of participatory culture, when an everywoman like Jane brings to the fore the need to be more involved in re-creative activities that are triggered by reading Austen’s novels.

  3. Radioactivity And Nuclear Themes In Croatian Popular Culture

    International Nuclear Information System (INIS)

    Franic, Z.; Franic, S.

    2015-01-01

    Popular culture refers to the entirety of ideas, perspectives, attitudes, behaviours, ways of communication, cultural and artistic products, (visual, auditory, written, etc.) as well as other phenomena in the real or virtual world within mainstream culture. Heavily influenced by mass media, this collection of ideas permeates the everyday lives of society. In the so-called atomic age, which corresponds to the cold war period, stylistic coloration and application of the concepts of radiation that have persisted in everyday life to this day can be classified into four main groups of radiological-nuclear themes: monsters and mutants associated with radiation, nuclear accidents, nuclear terrorism and nuclear optimism. This paper discusses some examples relating to radioactivity, radiation and nuclear topics in Croatian popular culture, with special reference to the mass media, including some Internet portals. In Croatian mass media, like in other cultures, radiation and nuclear metaphors symbolize something scary and completely incomprehensible. However, further systematic research would be needed to analyse and explain all of the stereotypes in more detail. Results would be useful in creating a more effective way for informing the general public about the effects and use of radiation and nuclear technology, which is expected to play a far greater role in solving numerous problems dealing with energy supply, medicine, etc. in the near future. It should be noted that nowadays the collective public fears shift from radiation to other global threats such as climate change, genetically modified organisms, global terrorism and others. (author).

  4. Themes of rural health and aging from a program of research.

    Science.gov (United States)

    Congdon, J G; Magilvy, J K

    2001-01-01

    The culture and diversity of rural life and limitations of rural health systems to meet the changing health needs of an aging population lead to problems of obtaining appropriate care in rural America. In a program of nursing research involving three ethnographic studies in rural Colorado, transitions of older adults across differing levels of heath care were explored. The sample totaled 425 participants, of whom 25% were Hispanic. Five major themes emerged: circles of formal and informal care; integration of faith, spirituality, and family with health status; crisis nature of health care transitions; nursing homes as a housing option; and changing spirit of traditional rural nursing. Recommendations for providers included making their practices congruent with rural culture, being fully informed of available resources, facilitating acceptable health care decisions, and integrating physical, mental, and spiritual health care for elders and their families.

  5. Sport as the Pragmatic Determiner, Motif and Theme of Pindaric Odes

    Directory of Open Access Journals (Sweden)

    Brane Senegačnik

    2015-07-01

    Full Text Available The vast majority of Pindar’s integrally preserved poetry is linked to sport: his epinicia, collected in four volumes, are dedicated to victors in various sporting disciplines at the four pan-Hellenic games. This is more than an external pragmatic circumstance: an obligatory constituent of the epinicium is the victor’s genealogy, often accompanied by a detailed account of the victor’s feat and career as well as the sporting achievements of his ancestors. Sporting success is a peak of human life, worth any exertion or cost, but even so it cannot lead to transcendence: it is a single moment blending into the shadow of transience. The sporting victory motif thus expands into the theme of human identity, which is in Pindar’s religious world crucially determined by man’s closeness or semblance to the gods on the one hand and the insurmountable difference on the other.

  6. 77 FR 43117 - Meeting of the Cold War Advisory Committee for the Cold War Theme Study

    Science.gov (United States)

    2012-07-23

    ... the Cold War Advisory Committee for the Cold War Theme Study AGENCY: National Park Service, Interior... Committee Act, 5 U.S.C. Appendix, that the Cold War Advisory Committee for the Cold War Theme Study will... National Park Service (NPS) concerning the Cold War Theme Study. DATES: The teleconference meeting will be...

  7. Teachers Working Cooperatively with Parents and Caregivers when Implementing LGBT Themes in the Elementary Classroom

    Science.gov (United States)

    Flores, Gabriel

    2014-01-01

    Many teachers are interested in having a more inclusive multicultural education that includes lesbian, gay, bisexual, and transgender (LGBT) themes and gay-themed children's literature; unfortunately, research has found that many teachers do not implement gay themes in their multicultural education curriculum because of fear of criticism from…

  8. Living in imaginary places: on the creation and consumption of themed residential architecture

    NARCIS (Netherlands)

    Meier, S.O.

    2013-01-01

    This study deals with theming of residential space and architecture. In theoretical terms, theming is defined as the application of a narrative to places and the built environment to make them more appealing than they otherwise would be. In a broader sense it is argued that theming is related to an

  9. Professional development themes in strength and conditioning coaches.

    Science.gov (United States)

    Tod, David A; Bond, Kath A; Lavallee, David

    2012-03-01

    The purpose of this study was to explore professional development themes in experienced strength and conditioning coaches. Strength and conditioning coaches (N = 15, mean age = 34.3 years, SD = 5.2 years) with 11.4 (SD = 4.9) years experience working with elite, professional, or talented athletes were interviewed about their professional development. The interviews were transcribed verbatim and content analyzed. Over time, subjects' service-delivery practices became more flexible and client driven. Their role understanding also broadened to include various dimensions, such as the need to consider various stakeholders and the value of good relationships with athletes. The subjects shifted from relying on external justification for professional decision making to their experience-based knowledge. The subjects believed athlete work experience, interactions with senior strength and conditioning coaches and other colleagues, the professional literature, and nonprofessional experiences, such as their own athletic experience and sales or managerial training, were the primary influences on their professional development. Typically, the subjects experienced anxiety about their competence, both early in their careers and when working in new contexts or with new athlete groups, but over time, they developed increased confidence. In addition, the subjects experienced reduced narcissism over time about the control they had over athletes and their competitive results. The current results provide information about the characteristics of effective strength and conditioning coaches, the ways they develop their competencies to help athletes, and the emotions they experience throughout their careers. These results may help strength and conditioning practitioners in planning and optimizing their professional development and effectiveness with athletes.

  10. From gametogenesis and stem cells to cancer: common metabolic themes.

    Science.gov (United States)

    Pereira, Sandro L; Rodrigues, Ana Sofia; Sousa, Maria Inês; Correia, Marcelo; Perestrelo, Tânia; Ramalho-Santos, João

    2014-01-01

    Both pluripotent stem cells (PSCs) and cancer cells have been described as having similar metabolic pathways, most notably a penchant for favoring glycolysis even under aerobiosis, suggesting common themes that might be explored for both stem cell differentiation and anti-oncogenic purposes. A search of the scientific literature available in the PubMed/Medline was conducted for studies on metabolism and mitochondrial function related to gametogenesis, early development, stem cells and cancers in the reproductive system, notably breast, prostate, ovarian and testicular cancers. Both PSCs and some types of cancer cells, particularly reproductive cancers, were found to obtain energy mostly by glycolysis, often reducing mitochondrial activity and oxidative phosphorylation. This strategy links proliferating cells, allowing for the biosynthesis reactions necessary for cell division. Interventions that affect metabolic pathways, and force cells to change their preferences, can lead to shifts in cell status, increasing either pluripotency or differentiation of stem cells, and causing cancer cells to become more or less aggressive. Interestingly metabolic changes in many cases seemed to lead to cell transformation, not necessarily follow it, suggesting a direct role of metabolic choices in influencing the (epi)genetic program of different cell types. There are uncanny similarities between PSCs and cancer cells at the metabolic level. Furthermore, metabolism may also play a direct role in cell status and targeting metabolic pathways could therefore be a promising strategy for both the control of cancer cell proliferation and the regulation of stem cell physiology, in terms of manipulating stem cells toward relevant phenotypes that may be important for tissue engineering, or making cancer cells become less tumorigenic. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For

  11. The effects of similarity of theme and instantiation in analogical reasoning.

    Science.gov (United States)

    Yanowitz, K L

    2001-01-01

    The influence of 2 types of structural similarity on analogical reasoning was examined. The theme of a story is a structural component that constrains other relationships in the story. Another structural component is the way in which the theme is implemented. Participants received pairs of stories that varied in the similarity of these two components. Participants in Experiment 1 judged stories containing similar themes as more analogous than stories with dissimilar themes. Likewise, stories with similar implementations were judged as more analogous than stories with dissimilar implementations. Experiment 2 revealed a similar pattern when participants had the opportunity to transfer information from source to target stories. Greater transfer was seen for stories with similar themes than for stories with dissimilar themes. Greater transfer was also seen for stories with similar implementations of different themes than for stories with different implementations.

  12. Belowground Carbon Cycling Processes at the Molecular Scale: An EMSL Science Theme Advisory Panel Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Hess, Nancy J.; Brown, Gordon E.; Plata, Charity

    2014-02-21

    As part of the Belowground Carbon Cycling Processes at the Molecular Scale workshop, an EMSL Science Theme Advisory Panel meeting held in February 2013, attendees discussed critical biogeochemical processes that regulate carbon cycling in soil. The meeting attendees determined that as a national scientific user facility, EMSL can provide the tools and expertise needed to elucidate the molecular foundation that underlies mechanistic descriptions of biogeochemical processes that control carbon allocation and fluxes at the terrestrial/atmospheric interface in landscape and regional climate models. Consequently, the workshop's goal was to identify the science gaps that hinder either development of mechanistic description of critical processes or their accurate representation in climate models. In part, this report offers recommendations for future EMSL activities in this research area. The workshop was co-chaired by Dr. Nancy Hess (EMSL) and Dr. Gordon Brown (Stanford University).

  13. The Theme of Beauty in Leopold Sedar Senghor's Poetry ...

    African Journals Online (AJOL)

    In his long and immensely successful career,1 Leopold Sedar Senghor celebrates the beauty of three major places or landmarks, namely, the African geographical landscape; the spirit and essence of womanhood, especially black womanhood; and the ethos of the dead ancestors. This essay is organized into three ...

  14. Substance Abuse and Prison Recidivism: Themes from Qualitative Interviews

    Science.gov (United States)

    Phillips, Lindsay A.

    2010-01-01

    This qualitative analysis explores the role of substance abuse in reentry from prison to society. Participants who recidivated (N = 20) in an urban prison system identified substance abuse as their primary reason for recidivism. Treatment implications are discussed.

  15. Literature overview highlights lack of paediatric donation protocols but identifies common themes that could guide their development

    NARCIS (Netherlands)

    Vileito, A; Siebelink, M J; Verhagen, A A E

    Aim: Paediatric donation is a unique and extremely sensitive process that requires specific knowledge and competencies. Most countries use protocols for organ and tissue donation to ensure optimal care for the donor and family, but these mainly focus on adults. However, the donation process for

  16. Analyzing Learner Characteristics, Undergraduate Experience and Individual Teamwork Knowledge, Skills and Abilities: Toward Identifying Themes to Promote Higher Workforce Readiness

    Science.gov (United States)

    Frederick, Consuelo V.

    2009-01-01

    With the world amidst globalization and economic flux affecting business, industry, and communities the need to work together becomes increasingly important. Higher education serves an important role in developing the individual teaming capabilities of the workforce. This environment is the time and place--opportunity for student personnel to…

  17. Future e-government research : 13 research themes identified in the eGovRTD2020 project

    NARCIS (Netherlands)

    Wimmer, M.; Codagnone, C.; Janssen, M.F.W.H.A.

    2008-01-01

    E-government research has become a recognized research domain and many policies and strategies are formulated for e-government implementations. Most of these target the next few years and limited attention has been giving to the long term. The eGovRTD2020, a European Commission co-funded project,

  18. The Balkan Theme in The Secret of Chimneys

    Directory of Open Access Journals (Sweden)

    Graham St. John Stott

    2016-06-01

    Full Text Available In The Secret of Chimneys (1925 Agatha Christie uses the all too familiar Balkan stereotypes of backwardness and brigandage, but not – as was usually the case at the time – as an Other to illustrate British virtue, but as a mirror to British vice. It is Britain, not the fictional Herzoslovakia, that is a nation of brigands. Herzoslovakia remains relatively unknown, as none of the novel’s scenes take place there, but it is described by disinterested observers as democratic and prosperous. In London, however, the Foreign Office plans to overthrow its government to secure oil rights promised by a royal heir-in-exile to a London-based financial consortium. Keywords: Christie, Balkans, Romania, oil, brigandsAgatha Christie’s The Secret of Chimneys (1925 has been faulted for being on the one hand a frothy mix of Anthony Hope and P. G. Wodehouse (Thompson 143 and on the other a mishmash of popular ethnic, national and regional stereotypes – including those of the Balkans (Todorova 122. It is, however, a far more subtle work than such accounts suggest. Though the influence of Hope and Wodehouse can certainly be seen in the novel’s story of princes in disguise (reminiscent of The Prisoner of Zenda and a country house setting that would have reminded readers of Blandings, its main plot addresses an important theme –and in exploring it Christie takes the Balkans very seriously. Oil has been found in the Republic of Herzoslovakia and the Foreign Office, represented by George Lomax, has secured the pledge of the exiled Prince Michael Obolovitch “to grant certain oil concessions” to a consortium led by Herman Isaacstein if the Obolovitchs are restored to power. In other words: to secure those concessions the British Government has committed itself to the overthrow of Herzoslovakia’s government. The Foreign Office’s interest in the Balkans might not have surprised Christie’s readers. The Anglo-Iranian Oil Company had held a monopoly on

  19. Life Themes and Interpersonal Motivational Systems in the Narrative Self-construction

    Science.gov (United States)

    Veglia, Fabio; Di Fini, Giulia

    2017-01-01

    What makes unique and unrepeatable individuals is their ability to write their own story attributing meaning, sharing it through narration, giving coherence to the information related to the interpersonal motivational systems, and creating alternative hierarchies to those biologically provided by the genetic code. Through clinical narratives and narrative literature, we can observe the recurrence of specific topics, across time and different cultures. Hence, we wondered whether there are some evolutionary suggestions that guide us in the construction of the narrative-autobiographical contents. In this article we proposed a theoretical-clinical hypothesis about the existence of a biological disposition to identify as fundamental six Life Themes (LTs) that contribute to defining the image of the self and the world: Love, Personal Value, Power, Justice, Truth, and Freedom. Besides the innumerable narratives dependent upon context, there may be many ways of telling stories that, instead, would be reported to these few essential themes. A narrative review of the literature about these concepts follows the systematic explanation of the perspective about the LTs as attractors of meaning. The manuscript considers also the process of co-construction of meanings within the interpersonal relationships and the influences of these on the narratives. In particular, we focused on the importance of episodic and autobiographical memory related to the attachment and significant figures, in the construction of the personal story and the LTs. We also explained the possible clinical implications of the theoretical hypothesis of LTs. Within clinical conversations, the LTs could be expressed rigidly or, otherwise, in a confused way. The lack of narrative integration may lead to the dominance of chaos or rigidity that generates suffering. A better comprehension of the LTs in patients’ narrations could be useful to identify a narrative profile about the areas of greatest suffering

  20. Genomewide association study identifies no major founder variant in ...

    Indian Academy of Sciences (India)

    2013-12-10

    Dec 10, 2013 ... variant in Caucasian moyamoya disease ... 1Department of Health and Environmental Sciences, Kyoto University Graduate ... a low prevalence in European countries (Goto and Yonekawa. 1992; Kuroda and Houkin 2008). We have found that the p.R4810K variant in the ring finger protein 213 (RNF213).

  1. Genomewide association study identifies no major founder variant in ...

    Indian Academy of Sciences (India)

    Young onset (<15 year). 14. –. Adult onset (≤15 year). 24. –. Clinical symptoms. Cerebral infarction. 18. –. TIAb. 6. –. Stroke. 3. –. Headache. 4. –. Hemorrhage. 1. –. Epilepsy. 2. –. Asymptomatic. 1. –. Otherc. 3. –. Clinical status. Bilateral. 35. –. Unilateral. 3. –. aSD, standard deviation; bTIA, transient ischemic attack; cother, ...

  2. Major roles for minor bacterial lipids identified by mass spectrometry.

    Science.gov (United States)

    Garrett, Teresa A

    2017-11-01

    Mass spectrometry of lipids, especially those isolated from bacteria, has ballooned over the past two decades, affirming in the process the complexity of the lipidome. With this has come the identification of new and interesting lipid structures. Here is an overview of several novel lipids, from both Gram-negative and Gram-positive bacteria with roles in health and disease, whose structural identification was facilitated using mass spectrometry. This article is part of a Special Issue entitled: Bacterial Lipids edited by Russell E. Bishop. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. The effects of gender, ethnicity, and a close relationship theme on perceptions of persons introducing a condom.

    Science.gov (United States)

    Castaneda, D M; Collins, B E

    1998-09-01

    Perceptions of persons who introduce condoms in an ongoing sexual interaction, and the effects of gender and ethnicity on these perceptions, were explored in a study involving 243 students at a large, urban university in the western US. 133 of these students identified themselves as Mexican American; the remaining students indicated they were White. A vignette methodology was used to elicit perceptions of condom introducers on six scales (Nice, Exciting, Sexually Attractive, Promiscuous, Good Relationship Partner, Unpersonable/Personable). Data were analyzed in a 2 (gender of participant) x 2 (gender of condom introducer) x 3 (low acculturated Mexican American, high acculturated Mexican American, White) x 2 (presence/absence of close relationship theme) analysis of variance and covariance. In terms of the Nice Scale, women rated condom introducers significantly higher than men, female condom introducers were rated significantly higher than male introducers, and condom introducers who expressed a care and responsibility theme while introducing a condom were rated significantly higher than those who expressed no theme. On the Exciting Scale, women condom introducers were rated significantly higher than men. Condom introducers who expressed a care and responsibility theme were rated significantly higher than those who expressed no theme on the Good Relationship Partner scale. Men rated the female condom introducer significantly higher than women on the Promiscuous scale. Low acculturated Mexicans rated the female condom introducer significantly higher than the male introducer on the Promiscuous scale and rated the condom introducer significantly higher than Whites on the Sexually Attractive scale. These findings attest that many often contradictory interpersonal gender- and ethnicity-related perceptions operate in sexual encounters.

  4. "The Voyage of the Dawn Treader": The World at the Dawn of 2006-2011. Understanding societal themes

    Directory of Open Access Journals (Sweden)

    Sanchen Henning

    2014-01-01

    Full Text Available This article offers a snapshot of the societal dynamics of individual countries around the world, integrated into a global view to provide the tourism and hospitality industry insight into potential customer needs and perceptions. The OPUS Reports on the Global Dynamics at the Dawn of 20...are published annually since 2006 in the Journal of Organisational and Social Dynamics in London. The researchers were interested in a metaphoric tour of the world's social dynamics over time as perceived from both the Systems psychodynamics and Positive psychology theoretical paradigms. The research methodology was qualitative using a case study approach where each of the six (2006- 2011 years' integrated hypotheses was studied as a separate case study. The six cases were integrated into new hypotheses reflecting how global social dynamics changed over the years. The findings were presented as hypotheses per individual country followed by an integrated global hypothesis. The three main emerging themes were framed as Identity, Hope and Love. Identity contains the sub-theme of Facelessness, described as the fragmentation of cultures, a loss of cultural identity and a search for shared social meaning. Hope embodies the theme Knight/s in shining armour which describes youth as saviours and Obama as saviour. The loss of Hope is illustrated by the sub-themes of the impotence of the older generation, pessimism, fear and the death of a way of life. Love consists of human connection described as affiliation, support and trust. The lack of Love consists of human alienation described as loneliness, aggression and violence. The findings of the study identify societal themes that can be operationalized in the tourism and hospitality industry through targeted offerings to provide in the unmet needs of society. In addition, training interventions to improve customer service and return on investment can be based on the findings of this research.

  5. Life-style themes of unwed pregnant adolescents who chose to keep their babies.

    Science.gov (United States)

    Jorgensen, J A; Newlon, B J

    1988-12-01

    The authors point out that the largest increase in birthrate is accounted for by girls under age 15; the rise in teenage baby keeping is also a major source of alarm in America. The subjects interviewed for this study were currently enrolled in a Teenage Parent Program for girls aged 14-18 in a large southwestern city. All participants in the study were Anglos from middle to lower-middle income families. Participants included 2 15-year-olds, 2 16-year-olds, 3 17-year-olds, and 3 18-year-olds. All were unwed and kept their babies after birth. Each subject participated in a tape-recorded interview which lasted from 30 minutes to 1 hour and included early recollections and birth order information. Transcripts were analyzed and interpreted by 3 expert Adlerian therapists. Examination of these transcripts revealed themes common to the group as a whole. These themes centered around the desire for a close, idealized relationship with someone, the goal of excitement, and the expectation of being confused, unknowing, or afraid. The group also demonstrated a lack of themes centering on their own anger or victimization. They did, however, perceive themselves as being isolated from their parents. Those subjects who shared the same birth order position tended to have specific traits in common. The youngest in terms of birth order tended to use their confusion to keep others involved with them. The only and 1st borough tended to use their confusion and fear to deflect the burden of responsibility which was a strong component of their life-style. Lack of self-esteem was 1 commonly held characteristic. If society wishes to change the current increase in teenage pregnancies, a greater understanding of the importance of belonging and self-worth is needed by the significant adults in young people's lives. Increased understanding could lead to changes within the family and the educational institution. Self-esteem in young people would be encouraged and a sense of belonging developed

  6. Incredible Years Parent and Teacher Programmes: Emerging Themes and Issues

    Science.gov (United States)

    Wetherall, Michelle

    2014-01-01

    This paper examines the Incredible Years Parent and Teacher Programmes that have originated from the work of Webster-Stratton. It provides a brief background on the programmes and a critical analysis of the issues as identified in current literature. The issues can be grouped into four main categories, the first being government decision-making…

  7. Research for food and health in Europe: themes, needs and proposals

    LENUS (Irish Health Repository)

    McCarthy, Mark

    2011-09-29

    Abstract Background Diet, in addition to tobacco, alcohol and physical exercise, is a major factor contributing to chronic diseases in Europe. There is a pressing need for multidisciplinary research to promote healthier food choices and better diets. Food and Health Research in Europe (FAHRE) is a collaborative project commissioned by the European Union. Among its tasks is the description of national research systems for food and health and, in work reported here, the identification of strengths and gaps in the European research base. Methods A typology of nine research themes was developed, spanning food, society, health and research structures. Experts were selected through the FAHRE partners, with balance for individual characteristics, and reported using a standardised template. Results Countries usually commission research on food, and on health, separately: few countries have combined research strategies or programmes. Food and health are also strongly independent fields within the European Commission\\'s research programmes. Research programmes have supported food and bio-technology, food safety, epidemiological research, and nutritional surveillance; but there has been less research into personal behaviour and very little on environmental influences on food choices - in the retail and marketing industries, policy, and regulation. The research is mainly sited within universities and research institutes: there is relatively little published research contribution from industry. Discussion National food policies, based on epidemiological evidence and endorsed by the World Health Organisation, recommend major changes in food intake to meet the challenge of chronic diseases. Biomedical and biotechnology research, in areas such as \\'nutrio-genomics\\

  8. Mathematical Communication Ability by Grade VII Students Using a Themed Problem Based Learning with Scaffolding on Rectangle Materials

    OpenAIRE

    Didik Adi Saputro; Masrukan Masrukan; Arief Agoestanto

    2017-01-01

    The aim of research to test students' mathematical communication used themed of PBL with scaffolding, themed of PBL and PBL achieve mastery learning;to test students' mathematical communication that used the themed of PBL with scaffolding, themed of PBL and PBL; and to test students' mathematical communication for the low, medium group, and a high-group themed of PBL with scaffolding, themed of PBL and PBL. This type of research is quantitative research. The Population is seventh grade studen...

  9. Wearout Effects of Different Advertising Themes: A Dynamic Bayesian Model of the Advertising-Sales Relationship

    OpenAIRE

    Frank M. Bass; Norris Bruce; Sumit Majumdar; B. P. S. Murthi

    2007-01-01

    Models of advertising response implicitly assume that the entire advertising budget is spent on disseminating one message. In practice, managers use different themes of advertising (for example, price advertisements versus product advertisements) and within each theme they employ different versions of an advertisement. In this study, we evaluate the dynamic effects of different themes of advertising that have been employed in a campaign. We develop a model that jointly considers the effects o...

  10. Green Logistic Practices: A Theoretical Approach of the Theme

    OpenAIRE

    Emanuele Engelage; Altair Borgert; Marcos Antonio De Souza

    2016-01-01

    This study aims to identify the main practices of green logistic considered in national and international academic literature. Using standard techniques for selection of previous studies, this study firts presents the definition of green logistic term in order to differentiate it from other concepts commonly treated similarly, as circular economy, the green chain management (GSCM), the reverse logistics and the environmental certifications (ISO 14001), to obtain clarity about their delimitati...

  11. [Predictive value of the VMS theme 'Frail elderly': delirium, falling and mortality in elderly hospital patients].

    Science.gov (United States)

    Oud, Frederike M M; de Rooij, Sophia E J A; Schuurman, Truus; Duijvelaar, Karlijn M; van Munster, Barbara C

    2015-01-01

    To determine the predictive value of safety management system (VMS) screening questions for falling, delirium, and mortality, as punt down in the VMS theme 'Frail elderly'. Retrospective observational study. We selected all patients ≥ 70 years who were admitted to non-ICU wards at the Deventer Hospital, the Netherlands, for at least 24 hours between 28 March 2011 and 10 June 2011. On admission, patients were screened with the VMS instrument by a researcher. Delirium and falls were recorded during hospitalisation. Six months after hospitalisation, data on mortality were collected. We included 688 patients with a median age of 78.7 (range: 70.0-97.1); 50.7% was male. The sensitivity of the screening for delirium risk was 82%, the specificity 62%. The sensitivity of the screening for risk of falling was 63%, the specificity 65%. Independent predictors for mortality within 6 months were delirium risk (odds ratio (OR): 2.3; 95% CI 1.1-3.2), malnutrition (OR: 2.1; 95% CI 1.3-3.5), admission to a non-surgical ward (OR: 3.0; 95% CI 1.8-5.1), and older age (OR: 1.1; 95%CI 1.0-1.1). Patients classified by the VMS theme 'Frail elderly' as having more risk factors had a higher risk of dying (p instrument for identifying those elderly people with a high risk of developing this condition; the VMS sensitivity for fall risk is moderate. The number of positive VMS risk factors correlates with mortality and may therefore be regarded as a measure of frailty.

  12. Rethinking Social Justice and Adult Education for Welcoming, Inclusive Communities: Synthesis of Themes

    Science.gov (United States)

    Lange, Elizabeth; Baillie Abidi, Catherine

    2015-01-01

    This chapter summarizes the key themes across the articles on transnational migration, social inclusion, and adult education, using Nancy Fraser's framework of redistributive, recognitive, and representational justice.

  13. Themes of Lust and Love in Popular Music Lyrics From 1971 to 2011

    Directory of Open Access Journals (Sweden)

    Yasaman Madanikia

    2014-08-01

    Full Text Available We explored themes related to sexual desire (lust and romantic desire (love in the lyrics of popular music over the past 40 years. We examined whether there have been changes in the prevalence of lust and love themes and changes in how these themes inter-relate in music lyrics over time. The study sample consisted of the top 40 songs of Billboard Year End Hot 100 single songs for every 5 years from 1971 to 2011 (N = 360. There was a linear decrease over time in the proportion of songs with a love theme and in the proportion of songs with a combination of lust and love themes. In contrast, there was a significant increase in the proportion of songs with a theme focusing on lust in the absence of love. Themes of lust in the absence of love were especially prevalent in hip-hop/rap music, although music genre did not account for the changing themes over time. These shifts in themes found in popular music may both influence cultural norms and reflect a cultural shift toward acceptance of sexuality outside of love relationships.

  14. Chemical Variations on the p53 Reactivation Theme

    Directory of Open Access Journals (Sweden)

    Carlos J. A. Ribeiro

    2016-05-01

    Full Text Available Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the “guardian of the genome”, playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors that retain wild-type p53 status, its function is usually inactivated by overexpression of negative regulators (e.g., MDM2 and MDMX. Hence, restoring p53 function in cancer cells represents a valuable anticancer approach. In this review, we will present an updated overview of the most relevant small molecules developed to restore p53 function in cancer cells through inhibition of the p53-MDMs interaction, or direct targeting of wild-type p53 or mutated p53. In addition, optimization approaches used for the development of small molecules that have entered clinical trials will be presented.

  15. Lines of resistance: evoking and configuring the theme of resistance in museum displays in Britain around the bicentenary of 1807

    Directory of Open Access Journals (Sweden)

    Geoffrey Cubitt

    2010-11-01

    Full Text Available On the basis of an extensive survey of museum displays and exhibitions dealing with slavery and abolition, put on at the time of the 2007 Bicentenary of the Act of Abolition, this article explores, and suggests ways of analysing, the ways in which museums in Britain presented, evoked and interpreted the theme of resistance or rebellion by the enslaved. By recognising the importance of resistance, museums aimed to affirm the agency of the enslaved and to counterbalance the celebratory tendencies of abolitionist historiography; they were also, in some cases, seeking to position themselves less as authoritative purveyors of knowledge than as arenas for the articulation of competing narratives and the negotiation of social and cultural identities. Yet museums’ efforts to foreground the theme of resistance were often limited in character: the importance of the theme was announced, but treatments of it were brief and schematic, dependent on a limited range of materials, and not always convincingly woven into the larger narratives of the exhibition. The article explores some of the reasons for this, before analysing in more detail the presentational strategies of a number of exhibitions which did develop a larger or more complex handling of the theme of resistance. Here the analysis uses a distinction between ‘gestural’ and ‘expository’ presentational emphases to map similarities and differences between these displays, and in particular between the strategies two new and major permanent exhibits opened in 2007: the International Slavery Museum in Liverpool and the re-designed Wilberforce House Museum in Hull.

  16. Audition and exhibition to toluene - a contribution for the theme

    Directory of Open Access Journals (Sweden)

    Kulay, Luiz Alexandre

    2012-01-01

    Full Text Available Introduction: With the technological advances and the changes in the productive processes, the workers are displayed the different physical and chemical agents in its labor environment. The toluene is solvent an organic gift in glues, inks, oils, amongst others. Objective: To compare solvent the literary findings that evidence that diligent displayed simultaneously the noise and they have greater probability to develop an auditory loss of peripheral origin. Method: Revision of literature regarding the occupational auditory loss in displayed workers the noise and toluene. Results: The isolated exposition to the toluene also can unchain an alteration of the auditory thresholds. These audiometric findings, for ototoxicity the exposition to the toluene, present similar audiograms to the one for exposition to the noise, what it becomes difficult to differentiate a audiometric result of agreed exposition - noise and toluene - and exposition only to the noise. Conclusion: The majority of the studies was projected to generate hypotheses and would have to be considered as preliminary steps of an additional research. Until today the agents in the environment of work and its effect they have been studied in isolated way and the limits of tolerance of these, do not consider the agreed expositions. Considering that the workers are displayed the multiples agent and that the auditory loss is irreversible, the implemented tests must be more complete and all the workers must be part of the program of auditory prevention exactly displayed the low doses of the recommended limit of exposition.

  17. Global Climate Change and Society: Scientific, Policy, and Philosophic Themes

    Science.gov (United States)

    Frodeman, R.; Bullock, M. A.

    2001-12-01

    The summer of 2001 saw the inauguration of the Global Climate Change and Society Program (GCCS), an eight week, NSF-funded experiment in undergraduate pedagogy held at the University of Colorado and the National Center for Atmospheric Research. Acknowledging from the start that climate change is more than a scientific problem, GCCS began with the simultaneous study of basic atmospheric physics, classical and environmental philosophy, and public policy. In addition to lectures and discussions on these subjects, our twelve undergraduates (majoring in the physical sciences, social sciences, and humanities) also participated in internships with scholars and researchers at NCAR, University of Colorado's Center of the American West, and the Colorado School of Mines, on specific issues in atmospheric science, science policy, and ethics and values. This talk will discuss the outcomes of GCCS: specifically, new insights into interdisciplinary pedagogy and the student creation of an extraordinary "deliverable," a group summary assessment of the global climate change debate. The student assessment called for an integrated discussion of both the science of climate change and the human values related to how we inhabit the world. The problems facing society today cannot be addressed through the single-minded adherence to science and technology; instead, society must develop new means of integrating the humanities and science in a meaningful dialogue about our common future.

  18. Analysis of the theme bullying in feminine magazines for teens

    Directory of Open Access Journals (Sweden)

    Ana Cláudia Bortolozzi Maia

    2014-04-01

    Full Text Available Practices of violence such as physical and verbal aggression, provocations, humiliations and exclusion that occur mainly among young people in schools are named as bullying and the aim of this qualitative-descriptive study was to investigate how this phenomenon is represented by magazines directed to teenage girls. The analysis was conducted in fifteen articles of four Brazilian magazines: Capricho, Todateen, Atrevida and Yes Teen through thematic categories: 1 Definitions and explanations about bullying; 2 Magazines’ proposals to the confrontation against bullying (2.1 Campaigns and orientations against bullying; 2.2 Advices about how to act in the presence of bullying; 2.3 Examples of “overcoming” to people who suffered bullying and 2.4 Advices given to people who practice bullying. It was identified the presence of hierarchies, stereotypes and the incentive to competition. There is the predominance of normative and excluding patterns, advices that individualize the issue and lack of critical reflection.

  19. Artificial soils and waste products. Theme report 2

    Energy Technology Data Exchange (ETDEWEB)

    O`Riordan, N.J. [Ove Arup and Partners, London (United Kingdom); Tammirinne, M. [Technical Research Centre of Finland (Finland); Skarzynska, K. [University of Agriculture, Krakow, (Poland)

    1995-05-01

    Increasing pressure to minimise waste, recycle and manage finite aggregate resources has lead to the use of waste materials for engineered fills. Techniques to deal with materials such as colliery waste and power station ashes are maturing. Other materials such as lime stabilised soils, tyre/soil and polystyrene soil mixtures are being investigated. As efforts to reduce waste continue, so greater demands will be placed upon engineered land filling. This report summarises current practice and applications in this important area of geotechnical activity. Increasing economic and political pressure to reduce waste will lead to the development of many hybrid soils and the reuse of waste materials in innovative ways: thereby extending the chain of utility. Major advances in the understanding of real soils and pore fluids will enable additives such as cements, shredded tyres, expanded polystyrene, etc, to be incorporated with confidence to produce useful and durable engineering materials with predictable behaviour. Large stockpiles of mineral wastes provide a potential source of secondary aggregates. A flexible approach to the specification of engineering materials is needed so that such waste can be reused. Evidence from the reuse of colliery and other waste materials suggests that tunneling spoil can be treated to produce potentially useful secondary aggregates. Material delivered to materials suggests that tunneling spoil can be trated to produce potentially useful secondary aggregates. Material delivered to landfill sites will become progressively higher in contamination content which will place greater demands upon containment systems. Formalised risk assessment of landfill containment systems will grow, and further research in definition of failure scenarios and probability of occurrence is necessary. (AB) 71 refs.

  20. Teaching Spiritual Themes to African American Children: A Picture Book Approach

    Science.gov (United States)

    Harris, Demetrius B.

    2017-01-01

    "Teaching Spiritual Themes to African American Children: A Picture Book Approach" is a research project that used picture books to teach the four spiritual themes, 1.) love, 2.) forgiveness, 3.) kindness, and 4.) perseverance. This project was conducted in an after school program at Fifth Baptist Church, on Cary St. in Richmond, VA. The…

  1. Treatment of the Theme Islam in German Geographical Education: Case Study of Bavarian Geographical Curriculum

    Science.gov (United States)

    Zecha, Stefanie; Popp, Stephan

    2014-01-01

    Several previous studies have looked at the treatment of Islam and Muslim culture in western curricula. However in Germany, especially in Bavaria where Muslim immigration has been growing since the 1990s, no recent research has covered this theme. As a first step, an exploratory study of Islamic themes in the curricula of Bavarian secondary…

  2. Theme issue on e-mental health: a growing field in internet research.

    Science.gov (United States)

    Riper, Heleen; Andersson, Gerhard; Christensen, Helen; Cuijpers, Pim; Lange, Alfred; Eysenbach, Gunther

    2010-12-19

    This theme issue on e-mental health presents 16 articles from leading researchers working on systems and theories related to supporting and improving mental health conditions and mental health care using information and communication technologies. In this editorial, we present the background of this theme issue, and highlight the content of this issue.

  3. Aligning Theme and Information Structure to Improve the Readability of Technical Writing

    Science.gov (United States)

    Moore, N. A. J.

    2006-01-01

    The readability of technical writing, and technical manuals in particular, especially for second language readers, can be noticeably improved by pairing Theme with Given and Rheme with New. This allows for faster processing of text and easier access to the "method of development" of the text. Typical Theme-Rheme patterns are described, and the…

  4. Using the Five Themes of Geography To Teach about Venezuela and Mexico.

    Science.gov (United States)

    Sunal, Cynthia Szymanski; Christensen, Lois

    Activities that employ the five themes of geography--location, place, relationships within places, movement, and regions--to teach about Venezuela and Mexico are described in this document. Each theme has objectives, a list of materials, and three types of activities--exploration, invention, and expansion. Background information on Venezuela and…

  5. Simulacra and simulation: double simulation at a North Song Dynasty theme park

    NARCIS (Netherlands)

    Ong, C.E.; Jin, Ge

    2017-01-01

    This paper examines an unusual type of ‘cultural theme park’, one that is not based on simulating existing cultural diversity or historical places, but based in some senses on a ‘double simulation’. The theme park is based on an historical painting assumed to represent the North Song Dynasty period

  6. Sex Differences and/in the Self: Classic Themes, Feminist Variations, Postmodern Challenges

    Science.gov (United States)

    Bohan, Janis S.

    2002-01-01

    This article examines perspectives on and intersections between two recurrent themes in the history of American psychology: sex differences and theories of self. These themes and certain connections between them are considered in three eras: early American psychology, feminist psychology coincident with the second wave of feminism, and the recent…

  7. Purine biosynthesis in archaea: variations on a theme

    Directory of Open Access Journals (Sweden)

    Brown Anne M

    2011-12-01

    Full Text Available Abstract Background The ability to perform de novo biosynthesis of purines is present in organisms in all three domains of life, reflecting the essentiality of these molecules to life. Although the pathway is quite similar in eukaryotes and bacteria, the archaeal pathway is more variable. A careful manual curation of genes in this pathway demonstrates the value of manual curation in archaea, even in pathways that have been well-studied in other domains. Results We searched the Integrated Microbial Genome system (IMG for the 17 distinct genes involved in the 11 steps of de novo purine biosynthesis in 65 sequenced archaea, finding 738 predicted proteins with sequence similarity to known purine biosynthesis enzymes. Each sequence was manually inspected for the presence of active site residues and other residues known or suspected to be required for function. Many apparently purine-biosynthesizing archaea lack evidence for a single enzyme, either glycinamide ribonucleotide formyltransferase or inosine monophosphate cyclohydrolase, suggesting that there are at least two more gene variants in the purine biosynthetic pathway to discover. Variations in domain arrangement of formylglycinamidine ribonucleotide synthetase and substantial problems in aminoimidazole carboxamide ribonucleotide formyltransferase and inosine monophosphate cyclohydrolase assignments were also identified. Manual curation revealed some overly specific annotations in the IMG gene product name, with predicted proteins without essential active site residues assigned product names implying enzymatic activity (21 proteins, 2.8% of proteins inspected or Enzyme Commission (E. C. numbers (57 proteins, 7.7%. There were also 57 proteins (7.7% assigned overly generic names and 78 proteins (10.6% without E.C. numbers as part of the assigned name when a specific enzyme name and E. C. number were well-justified. Conclusions The patchy distribution of purine biosynthetic genes in archaea is

  8. Comparative phenomena about phraseology in the animal theme field

    Directory of Open Access Journals (Sweden)

    Lindita Çifçi

    2016-07-01

    Full Text Available Every language has its own history and structure of development and it is in a gradual and continuous process of change moving in an unconscious way from one kind to another, so in different languages we distinguish analogical development. Saphir (1912 was one of the first linguistics and anthropologists who developed the linguistic discipline and in an interlingual comparison he identified that languages differ from one another, but some differ more than others. Phraseological units deriving from a certain language do not remain isolated within the same language. They travel from one language to another due to relationships between people and languages. This happens because during these centennial relationships, people have exchanged not only goods, but even cultural values. As a result in our first steps of research there is a need to know and decide on phraseological types in each language, as well as comparison with other languages, to find out what is common and what is special among them. One of the main reasons of analogies in phraseology stays on similar or approximate concepts of objects and features of everyday life. Having into consideration the fact that the main source of phraseological units is the material world with a great variety and a wide range of clothes, tools, domestic animals, parts of human body, food and cooking, weapons and hunting objects, tribal relationships, job processes etc. we are going to analyse in this manuscript this phraseological phenomena.

  9. The role of play themes in non-directive play therapy.

    Science.gov (United States)

    Ryan, Virginia; Edge, Andrew

    2012-07-01

    Describing the processes underlying play therapy is important for evidence based practice in child therapy. Employing play themes to describe children's play session contents is in widespread use by practitioners, but an adequate classification of these themes for non-directive play therapy practice has not yet been established. This article sets out to fill this gap by first describing how themes can be distinguished and distilled from the contents of play therapy contents. Second, a classification of main themes and sub-themes with exemplars to illustrate these concepts which is compatible with non-directive play therapy practice is set out. Finally a pilot project with experienced play therapists to test this classification in practice is suggested, along with the research questions that will need to be investigated in the shorter and longer terms.

  10. Creative choices and fan practices in the transformation of theme park space

    Directory of Open Access Journals (Sweden)

    Carissa Ann Baker

    2016-09-01

    Full Text Available This article describes and interprets fan activities within the theme park space related to a particular fan object. It examines an evolving paradigm wherein the role of theme park visitors is changed. Rather than being perceived as observers of spectacles, they can participate and interact with the environment in new ways. An example of this is Sorcerers of the Magic Kingdom (2012, an interactive role-playing quest and collector card game at Disney's Magic Kingdom Park in Florida. Fans participate in a variety of practices that have dynamically redefined theme park activities. Together, management, designers, and fans have cocreated and reconstructed the theme park experience as one of exploration and participation. Despite multiple levels of control, fans will likewise persist in engagement with activities (in park and online that help shape and interrogate the theme park space.

  11. Big data - smart health strategies. Findings from the yearbook 2014 special theme.

    Science.gov (United States)

    Koutkias, V; Thiessard, F

    2014-08-15

    To select best papers published in 2013 in the field of big data and smart health strategies, and summarize outstanding research efforts. A systematic search was performed using two major bibliographic databases for relevant journal papers. The references obtained were reviewed in a two-stage process, starting with a blinded review performed by the two section editors, and followed by a peer review process operated by external reviewers recognized as experts in the field. The complete review process selected four best papers, illustrating various aspects of the special theme, among them: (a) using large volumes of unstructured data and, specifically, clinical notes from Electronic Health Records (EHRs) for pharmacovigilance; (b) knowledge discovery via querying large volumes of complex (both structured and unstructured) biological data using big data technologies and relevant tools; (c) methodologies for applying cloud computing and big data technologies in the field of genomics, and (d) system architectures enabling high-performance access to and processing of large datasets extracted from EHRs. The potential of big data in biomedicine has been pinpointed in various viewpoint papers and editorials. The review of current scientific literature illustrated a variety of interesting methods and applications in the field, but still the promises exceed the current outcomes. As we are getting closer towards a solid foundation with respect to common understanding of relevant concepts and technical aspects, and the use of standardized technologies and tools, we can anticipate to reach the potential that big data offer for personalized medicine and smart health strategies in the near future.

  12. The Power of a Creative Theme: A Large-scale Study of the Implications of Working with a “Forced” Creative Theme in Strategic Partnerships

    DEFF Research Database (Denmark)

    Schmeltz, Line; Kjeldsen, Anna Karina

    the process of applying for and becoming Capital of Culture, to the subsequent processes of establishing strategic partnerships between the Aarhus 2017 Foundation (the commercial foundation in charge of planning and running the mega event) and the wide range of partners (e.g. public organizations, cultural......In 2017, Denmark’s second largest city, Aarhus, holds the title as European Capital of Culture. From the initial project proposal, a significant part of the strategy for the mega event has been centered around the chosen theme; “Rethink”. The theme has thus been a continuous, common thread from......, a predetermined theme in strategic partnerships, vis-à-vis co-branding. Most often, the choice to enter into a co-branding process would be established by partners supporting one another in reaching a shared goal on the basis of shared values. But here, the value-base is already decided upon by the Aarhus 2017...

  13. Seeking Help in Domestic Violence Among Muslim Women in Muslim-Majority and Non-Muslim-Majority Countries: A Literature Review.

    Science.gov (United States)

    Afrouz, Rojan; Crisp, Beth R; Taket, Ann

    2018-01-01

    Women from different backgrounds and cultures are at risk of domestic violence. Disclosing the abusive experience and seeking help is not straightforward and easy and might be a complicated and long-term process. Muslim women, like other groups of women, may face various barriers to disclose abusive relationships and for seeking help. Some of the barriers may be common for the majority of Muslim women in different contexts, while others might be related to women's situations and the wider society they live. To identify these barriers and make recommendations for future studies, this article reviews related papers conducted in both Muslim-majority and non-Muslim-majority countries. A critical systematic review of the literature was conducted for identifying Muslim women's barriers in disclosing abuse and seeking help. Twenty-one studies met the inclusion criteria. The main identified barriers are discussed into under four themes: social context, family context, individual factors, and expectations of service providers. Although the researchers tried to investigate various barriers in seeking help, many of them have not focused on structural obstacles. Besides, in many Muslim-majority countries, the issue has not been explored. Therefore, the results of the current article will not apply to those countries. Recommendation for future research comprises more qualitative research compatible with the women's cultures and backgrounds in different societies, focusing more on structural and cultural factors to explore and find women's barriers to seek help.

  14. Barriers and facilitators of adherence to antidepressants among outpatients with major depressive disorder: A qualitative study.

    Science.gov (United States)

    Ho, Siew Ching; Jacob, Sabrina Anne; Tangiisuran, Balamurugan

    2017-01-01

    One of the major challenges in treating major depressive disorder (MDD) is patients' non-adherence to medication. This study aimed to explore the barriers and facilitators of patients' adherence to antidepressants among outpatients with MDD. Semi-structured and individual in-depth interviews were conducted among patients with MDD who were taking antidepressants, in the psychiatric clinic of a government-run hospital in Malaysia. Participants were purposively sampled from different genders and ethnicities. Interviews were conducted using a validated topic guide, and responses were audio-recorded, transcribed verbatim, checked, and analyzed using the grounded theory approach. A total of 30 patients were interviewed. Forty different themes and sub-themes were identified which were conceptually divided into two distinct categories related to barriers and facilitators to adherence. The barriers were: patient-specific, medication-specific, healthcare provision and system, social-cultural, and logistics. The facilitators were: having insight, perceived health benefits, regular activities, patient-provider relationship, reminders, and social support networks. Patient-specific barriers and medication side effects were the major challenges for adhering to treatment. Perceived health benefits and having insight on the need for treatment were the most frequently cited facilitators. Targeted interventions should be developed to address the key barriers, and promote measures to facilitate adherence in this group of patients.

  15. Some mechanistic requirements for major transitions.

    Science.gov (United States)

    Schuster, Peter

    2016-08-19

    Major transitions in nature and human society are accompanied by a substantial change towards higher complexity in the core of the evolving system. New features are established, novel hierarchies emerge, new regulatory mechanisms are required and so on. An obvious way to achieve higher complexity is integration of autonomous elements into new organized systems whereby the previously independent units give up their autonomy at least in part. In this contribution, we reconsider the more than 40 years old hypercycle model and analyse it by the tools of stochastic chemical kinetics. An open system is implemented in the form of a flow reactor. The formation of new dynamically organized units through integration of competitors is identified with transcritical bifurcations. In the stochastic model, the fully organized state is quasi-stationary whereas the unorganized state corresponds to a population with natural selection. The stability of the organized state depends strongly on the number of individual subspecies, n, that have to be integrated: two and three classes of individuals, [Formula: see text] and [Formula: see text], readily form quasi-stationary states. The four-membered deterministic dynamical system, [Formula: see text], is stable but in the stochastic approach self-enhancing fluctuations drive it into extinction. In systems with five and more classes of individuals, [Formula: see text], the state of cooperation is unstable and the solutions of the deterministic ODEs exhibit large amplitude oscillations. In the stochastic system self-enhancing fluctuations lead to extinction as observed with [Formula: see text] Interestingly, cooperative systems in nature are commonly two-membered as shown by numerous examples of binary symbiosis. A few cases of symbiosis of three partners, called three-way symbiosis, have been found and were analysed within the past decade. Four-way symbiosis is rather rare but was reported to occur in fungus-growing ants. The model

  16. Space weather in the EU’s FP7 Space Theme

    Directory of Open Access Journals (Sweden)

    Chiarini Paola

    2013-11-01

    Full Text Available Technological infrastructures in space and on ground provide services on which modern society and economies rely. Space weather related research is funded under the 7th Framework Programme for Research and Innovation (FP7 of the European Union in response to the need of protecting such critical infrastructures from the damage which could be caused by extreme space weather events. The calls for proposals published under the topic “Security of space assets from space weather events” of the FP7 Space Theme aimed to improve forecasts and predictions of disruptive space weather events as well as identify best practices to limit the impacts on space- and ground-based infrastructures and their data provision. Space weather related work was also funded under the topic “Exploitation of space science and exploration data”, which aims to add value to space missions and Earth-based observations by contributing to the effective scientific exploitation of collected data. Since 2007 a total of 20 collaborative projects have been funded, covering a variety of physical phenomena associated with space weather, from ionospheric disturbances and scintillation, to geomagnetically induced currents at Earth’s surface, to coronal mass ejections and solar energetic particles. This article provides an overview of the funded projects, touching upon some results and referring to specific websites for a more exhaustive description of the projects’ outcomes.

  17. Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme.

    Science.gov (United States)

    Chinopoulos, Christos; Adam-Vizi, Vera

    2006-02-01

    The interplay among reactive oxygen species (ROS) formation, elevated intracellular calcium concentration and mitochondrial demise is a recurring theme in research focusing on brain pathology, both for acute and chronic neurodegenerative states. However, causality, extent of contribution or the sequence of these events prior to cell death is not yet firmly established. Here we review the role of the alpha-ketoglutarate dehydrogenase complex as a newly identified source of mitochondrial ROS production. Furthermore, based on contemporary reports we examine novel concepts as potential mediators of neuronal injury connecting mitochondria, increased [Ca2+]c and ROS/reactive nitrogen species (RNS) formation; specifically: (a) the possibility that plasmalemmal nonselective cationic channels contribute to the latent [Ca2+]c rise in the context of glutamate-induced delayed calcium deregulation; (b) the likelihood of the involvement of the channels in the phenomenon of 'Ca2+ paradox' that might be implicated in ischemia/reperfusion injury; and (c) how ROS/RNS and mitochondrial status could influence the activity of these channels leading to loss of ionic homeostasis and cell death.

  18. OSCAAR calculations for the Hanford dose reconstruction scenario of BIOMASS Theme 2

    International Nuclear Information System (INIS)

    Homma, Toshimitsu; Tomita, Kenichi

    2000-10-01

    This report presents the results obtained from the application of the accident consequence assessment code, called OSCAAR, developed in Japan Atomic Energy Research Institute to the Hanford dose reconstruction scenario of BIOMASS Theme 2 organized by International Atomic Energy Agency. The scenario relates to an inadvertent release of 131 I to atmosphere from the Hanford Purex Chemical Separations Plant on 2-5 September 1963. This exercise was used to test the atmospheric dispersion and deposition models and food chain transport models for 131 I in OSCAAR with actual measurements and to identify the most important sources of uncertainty with respect both to the part of the assessment and to the overall assessment. The OSCAAR food chain model performed relatively well, while the atmospheric dispersion and deposition calculations made using wind data at the release height and wind fields by simple interpolation of the surrounding surface wind data indicated limited capabilities. The Monte Carlo based uncertainty and sensitivity method linked with OSCAAR successfully demonstrated its usefulness in the scenario. The method presented here also allowed the determination of the parameters that have the most important impact in accident consequence assessments. (author)

  19. OSCAAR calculations for the Iput dose reconstruction scenario of BIOMASS theme 2

    International Nuclear Information System (INIS)

    Homma, Toshimitsu; Matsunaga, Takeshi

    2001-01-01

    This report presents the results obtained from the application of the accident consequence assessment code, called OSCAAR, developed in Japan Atomic Energy Research Institute to the Iput dose reconstruction scenario of BIOMASS Theme 2 organized by International Atomic Energy Agency. The Iput Scenario deals with 137 Cs contamination of the catchment basin and agricultural area in the Bryansk Region of Russia, which was heavily contaminated after the Chernobyl accident. This exercise was used to test the chronic exposure pathway models in OSCAAR with actual measurements and to identify the most important sources of uncertainly with respect to each part of the assessment. The OSCAAR chronic exposure pathway models almost successfully reconstructed the whole 10-year time course of 137 Cs activity concentrations in most requested types of agricultural products and natural foodstuffs. Modeling of 137 Cs downward migration in soils is, however, still incomplete and more detail modeling of the changes of cesium bioavailability with time is needed for long term predictions of the contamination of food. (author)

  20. OSCAAR calculations for the Iput dose reconstruction scenario of BIOMASS theme 2

    Energy Technology Data Exchange (ETDEWEB)

    Homma, Toshimitsu; Matsunaga, Takeshi [Department of Reactor Safety Research, Nuclear Safety Research Center, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan)

    2001-01-01

    This report presents the results obtained from the application of the accident consequence assessment code, called OSCAAR, developed in Japan Atomic Energy Research Institute to the Iput dose reconstruction scenario of BIOMASS Theme 2 organized by International Atomic Energy Agency. The Iput Scenario deals with {sup 137}Cs contamination of the catchment basin and agricultural area in the Bryansk Region of Russia, which was heavily contaminated after the Chernobyl accident. This exercise was used to test the chronic exposure pathway models in OSCAAR with actual measurements and to identify the most important sources of uncertainly with respect to each part of the assessment. The OSCAAR chronic exposure pathway models almost successfully reconstructed the whole 10-year time course of {sup 137}Cs activity concentrations in most requested types of agricultural products and natural foodstuffs. Modeling of {sup 137}Cs downward migration in soils is, however, still incomplete and more detail modeling of the changes of cesium bioavailability with time is needed for long term predictions of the contamination of food. (author)

  1. A Network of Themes: A Qualitative Approach to Gerhard Richter's Text

    Directory of Open Access Journals (Sweden)

    Narvika Bovcon

    2017-07-01

    Full Text Available Gerhard Richter's books Text – a collection of painter's verbal statements about his artistic method – and Atlas – 783 sheets with images, mainly photographs and visual notations – are two archives that complement the understanding of his diverse artistic practice. The paper presents a textual model that experimentally simulates a possible ordering principle for archives. Richter's statements in the book Text are cut up and used as short quotations. Those that relate to multiple aspects of the painter's oeuvre are identified as hubs in the semantic network. The hubs are organized paratactically, as an array of different themes. The paper presents a methodological hypothesis and an experimental model that aim to connect the research of real networks with the paradigms of humanistic interpretation. We have to bear in mind that the network is a result of the researcher's interpretative approach, which is added to the initial archive included in the book Text. The breaking up of Richter's poetics into atoms of quotations is an experimental proposal of a new textuality in art history and humanities, which has its own history. In comparison to digital archives with complex interfaces that often tend to obscure the content, the elements in our experiment appear as specific configurations of the semantic network and are presented in a limited number of linear texts. The method of listing of quotations gathers the fragments into a potential “whole”, i.e. a narrativized gateway to an archive according to the researcher's interpretation.

  2. OSCAAR calculations for the Hanford dose reconstruction scenario of BIOMASS Theme 2

    Energy Technology Data Exchange (ETDEWEB)

    Homma, Toshimitsu; Tomita, Kenichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Inoue, Yoshihisa [Visible Information Center Inc., Tokai, Ibaraki (Japan)

    2000-10-01

    This report presents the results obtained from the application of the accident consequence assessment code, called OSCAAR, developed in Japan Atomic Energy Research Institute to the Hanford dose reconstruction scenario of BIOMASS Theme 2 organized by International Atomic Energy Agency. The scenario relates to an inadvertent release of {sup 131}I to atmosphere from the Hanford Purex Chemical Separations Plant on 2-5 September 1963. This exercise was used to test the atmospheric dispersion and deposition models and food chain transport models for {sup 131}I in OSCAAR with actual measurements and to identify the most important sources of uncertainty with respect both to the part of the assessment and to the overall assessment. The OSCAAR food chain model performed relatively well, while the atmospheric dispersion and deposition calculations made using wind data at the release height and wind fields by simple interpolation of the surrounding surface wind data indicated limited capabilities. The Monte Carlo based uncertainty and sensitivity method linked with OSCAAR successfully demonstrated its usefulness in the scenario. The method presented here also allowed the determination of the parameters that have the most important impact in accident consequence assessments. (author)

  3. Assessment report on NRP sub-theme 'National instruments for climate change policy'

    International Nuclear Information System (INIS)

    Verbruggen, H.; Nentjes, A.; Backhaus, J.G.; Jansen, H.M.A.

    1995-01-01

    Economic instruments for environmental protection feature in textbooks for their superior performance in terms of effectiveness and both static and dynamic efficiency, especially in cases characterized by a large number of polluters with large differences in abatement cost. These instruments are thus pre-eminently suited to be included in climate change policies. However, this proves to be very difficult as yet. The projects under this research sub-theme share a common interest in the complexities of implementing various types of economic instruments. The first project deals with the design of a European system of tradable emission rights. The second project is on the feasibility of ecological tax reform, with special reference to The Netherlands. The Climate Fund project, the third project, aims at investigating whether an international fund for side payments is an effective and efficient tool to reduce CO2 emissions. To that purpose, the world is divided into 9 regions. Finally, the fourth project uses an applied general equilibrium model to analyze the effectiveness and especially the income distributional effects of differently designed CO2 charges. The projects yield interesting results from which policy makers can benefit. There still are, however, blind spots. These and further research questions are identified. 4 refs

  4. [The theme of disaster in health care: profile of technical and scientific production in the specialized database on disasters of the Virtual Health Library - VHL].

    Science.gov (United States)

    Rocha, Vania; Ximenes, Elisa Francioli; Carvalho, Mauren Lopes de; Alpino, Tais de Moura Ariza; Freitas, Carlos Machado de

    2014-09-01

    In the specialized database of the Virtual Health Library (VHL), the DISASTER database highlights the importance of the theme for the health sector. The scope of this article is to identify the profiles of technical and scientific publications in the specialized database. Based on systematic searches and the analysis of results it is possible to determine: the type of publication; the main topics addressed; the most common type of disasters mentioned in published materials, countries and regions as subjects, historic periods with the most publications and the current trend of publications. When examining the specialized data in detail, it soon becomes clear that the number of major topics is very high, making a specific search process in this database a challenging exercise. On the other hand, it is encouraging that the disaster topic is discussed and assessed in a broad and diversified manner, associated with different aspects of the natural and social sciences. The disaster issue requires the production of interdisciplinary knowledge development to reduce the impacts of disasters and for risk management. In this way, since the health sector is a interdisciplinary area, it can contribute to knowledge production.

  5. Using Multiple Sources of Data to Gauge Outcome Differences between Academic-Themed and Transition-Themed First-Year Seminars

    Science.gov (United States)

    Zerr, Ryan J.; Bjerke, Elizabeth

    2016-01-01

    Students in two different types of first-year experience seminar courses at a moderately sized public university were compared using a large variety of measures--both direct and indirect. One of these first-year experience types was a three-credit academic-themed course offered in sections with variable content; the other was a two-credit…

  6. SPARQL-enabled identifier conversion with Identifiers.org

    Science.gov (United States)

    Wimalaratne, Sarala M.; Bolleman, Jerven; Juty, Nick; Katayama, Toshiaki; Dumontier, Michel; Redaschi, Nicole; Le Novère, Nicolas; Hermjakob, Henning; Laibe, Camille

    2015-01-01

    Motivation: On the semantic web, in life sciences in particular, data is often distributed via multiple resources. Each of these sources is likely to use their own International Resource Identifier for conceptually the same resource or database record. The lack of correspondence between identifiers introduces a barrier when executing federated SPARQL queries across life science data. Results: We introduce a novel SPARQL-based service to enable on-the-fly integration of life science data. This service uses the identifier patterns defined in the Identifiers.org Registry to generate a plurality of identifier variants, which can then be used to match source identifiers with target identifiers. We demonstrate the utility of this identifier integration approach by answering queries across major producers of life science Linked Data. Availability and implementation: The SPARQL-based identifier conversion service is available without restriction at http://identifiers.org/services/sparql. Contact: sarala@ebi.ac.uk PMID:25638809

  7. SPARQL-enabled identifier conversion with Identifiers.org.

    Science.gov (United States)

    Wimalaratne, Sarala M; Bolleman, Jerven; Juty, Nick; Katayama, Toshiaki; Dumontier, Michel; Redaschi, Nicole; Le Novère, Nicolas; Hermjakob, Henning; Laibe, Camille

    2015-06-01

    On the semantic web, in life sciences in particular, data is often distributed via multiple resources. Each of these sources is likely to use their own International Resource Identifier for conceptually the same resource or database record. The lack of correspondence between identifiers introduces a barrier when executing federated SPARQL queries across life science data. We introduce a novel SPARQL-based service to enable on-the-fly integration of life science data. This service uses the identifier patterns defined in the Identifiers.org Registry to generate a plurality of identifier variants, which can then be used to match source identifiers with target identifiers. We demonstrate the utility of this identifier integration approach by answering queries across major producers of life science Linked Data. The SPARQL-based identifier conversion service is available without restriction at http://identifiers.org/services/sparql. © The Author 2015. Published by Oxford University Press.

  8. Characterization of Fashion Themes Using Fuzzy Techniques for Designing New Human Centered Products

    Directory of Open Access Journals (Sweden)

    Y. Zhu

    2010-10-01

    Full Text Available Fabric selection plays an important role in fashion garment design. Designers often use both physical and normalized linguistic criteria for fabric selection. Perception and preference of consumers in their specific sociocultural context, expressed by fashion themes or emotional linguistic criteria, affect greatly new fashion product design. Modeling the relationship between linguistic design criteria and fashion themes of a brand image perceived by consumers becomes thus significant. For setting up this model, we first use fuzzy relations and correlation techniques to select the most relevant linguistic design criteria of fabric hand for each specific fashion theme. The selected criteria can then effectively reduce the complexity of the model and interpret consumer perception of fabrics. Finally, we use a weighted aggregation operator to predict the similarity degree between any new product and fashion themes. Compared with other models, the proposed method is more robust and easier to be interpreted with real data collected for design of senior T-shirt fabrics.

  9. A Critical Analysis of Global Competition in Higher Education: Synthesizing Themes

    Science.gov (United States)

    Portnoi, Laura M.; Bagley, Sylvia S.

    2014-01-01

    In this final chapter of the volume, the editors synthesize key themes that emerge from the preceding chapters. They also highlight the contributions the authors make through emphasizing critical perspectives and the tension between global and local forces.

  10. Hindemith: Symphonic Metamorphosis on Themes of Carl Maria von Weber / Jonathan Swain

    Index Scriptorium Estoniae

    Swain, Jonathan

    1990-01-01

    Uuest heliplaadist "Hindemith: Symphonic Metamorphosis on Themes of Carl Maria von Weber, Mathis der Maler - Symphony, Nobilissima visione - suite. Atlanta Symphony Orchestra, Yoel Levi" Telarc/ Conifer CD 80 195

  11. Migrations of theory, method and practice: a reflection on themes in migration studies (Review article)

    OpenAIRE

    Palmary, Ingrid

    2009-01-01

    In this review article, I offer some reflection on three themes in migration research, namely, the categorisation and quantification of migration, the role of trauma and distress in such categorisation, and the feminisation of migration. I was prompted to explore these three themes after reading a recent publication on migration in southern Africa (edited by Kok, Gelderblom, Oucho and Van Zyl, 2006). In this paper I raise these as three areas that appear to be determining the boundaries of th...

  12. A Political Campaign Strategy and Campaign Theme : How to Win a Political Campaign

    OpenAIRE

    河村, 直幸; Kawamura, Naoyuki

    2004-01-01

    The aim of this research paper is to introduce a political campaign strategy. A political campaign should do on a scientific system and needs effective strategy. Before political campaign begin, a candidate and its campaigner needs to analyze election district and sample voter opinion. An election campaign needs campaign theme. The creation of campaign theme needs careful and elaborate planning. A style of campaign varies according to incumbent or challenger. The developing of an effective po...

  13. Pedagogical workshops as a teaching and learning strategy: the hydrographic basic as a theme

    OpenAIRE

    Valéria Brumato Regina Fornazari; Ana Tiyomi Obara

    2017-01-01

    Current research investigates the ideas and practices of a team of teachers of the Natural Sciences working in schools in the state of Paraná, Brazil, with regard to pedagogical workshops as teaching and learning strategies on Hydrographic Basin as theme. A continuous formation course was conducted on the theme, with data retrieved by a questionnaire applied prior to the course and after the development of workshops by the teachers. Films, recordings and descriptive memorials were analyzed ac...

  14. THE EVOLUTION OF THE KREBS CYCLE: A PROMISING THEME FOR MEANINGFUL BIOCHEMISTRY LEARNING IN BIOLOGY

    Directory of Open Access Journals (Sweden)

    C. Costa

    2015-08-01

    Full Text Available INTRODUCTION: Evolution has been recognized as a key concept for biologists. In order to motivate biology undergraduates for contents of central energetic metabolism, we addressed the Krebs cycle structure and functions to an evolutionary view. To this end, we created a study guide which contextualizes the emergence of the cyclic pathway, in light of the prokaryotic influence since early Earth anaerobic condition to oxygen rise in atmosphere. OBJECTIVES: The main goal is to highlight the educational potential of the material whose subject is scarcely covered in biochemistry textbooks. MATERIALS AND METHODS: The study guide is composed by three interrelated sections, the problem (Section 1, designed to arouse curiosity, inform and motivate students; an introductory text (Section 2 about life evolution, including early micro-organisms and Krebs cycle emergence, and questions (Section 3 for debate. The activity consisted on a peer discussion session, with instructors tutoring. The questions were designed to foster exchange of ideas in an ever-increasing level of complexity, and cover subjects from early atmospheric conditions to organization of the metabolism along the subsequent geological ages. RESULTS AND DISCUSSION: We noticed that students were engaged and motivated by the task, especially during group discussion. Based on students’ feedbacks and class observations, we learned that the material raised curiosity and stimulated discussion among peers. It brought a historical and purposeful way of dealing with difficult biochemical concepts. CONCLUSIONS: The whole experience suggests that the study guide was a stimulus for broadening comprehension of the Krebs cycle, reinforcing the evolutionary stance as an important theme for biology and biochemistry understanding. On the other hand, we do not underestimate the fact that approaching Krebs cycle from an evolutionary standpoint is a quite complex discussion for the majority of students

  15. No such thing as mental illness? Critical reflections on the major ideas and legacy of Thomas Szasz.

    Science.gov (United States)

    Benning, Tony B

    2016-12-01

    Enfant terrible of psychiatry and widely known as one of its most indefatigable as well as iconoclastic critics, Thomas Szasz (1961-2012) had a prolific writing career that extended some 51 years beyond the publication of his first book, The Myth of Mental Illness , in 1961. This editorial identifies and critically discusses three major themes in Szasz's writings: his contention that there is no such thing as mental illness, his contention that individual responsibility is never compromised in those suffering from what is generally considered as mental illness, and his perennial interest in calling attention to the political nature of psychiatric diagnosis.

  16. Internally readable identifying tag

    International Nuclear Information System (INIS)

    Jefferts, K.B.; Jefferts, E.R.

    1980-01-01

    A method of identifying non-metallic objects by means of X-ray equipment is described in detail. A small metal pin with a number of grooves cut in a pre-determined equi-spaced pattern is implanted into the non-metallic object and by decoding the groove patterns using X-ray equipment, the object is uniquely identified. A specific example of such an application is in studying the migratory habits of fish. The pin inserted into the snout of the fish is 0.010 inch in diameter, 0.040 inch in length with 8 possible positions for grooves if spaced 0.005 inch apart. With 6 of the groove positions available for data, the capacity is 2 6 or 64 combinations; clearly longer pins would increase the data capacity. This method of identification is a major advance over previous techniques which necessitated destruction of the fish in order to recover the identification tag. (UK)

  17. Research for food and health in Europe: themes, needs and proposals

    Directory of Open Access Journals (Sweden)

    McKenna Brian

    2011-09-01

    Full Text Available Abstract Background Diet, in addition to tobacco, alcohol and physical exercise, is a major factor contributing to chronic diseases in Europe. There is a pressing need for multidisciplinary research to promote healthier food choices and better diets. Food and Health Research in Europe (FAHRE is a collaborative project commissioned by the European Union. Among its tasks is the description of national research systems for food and health and, in work reported here, the identification of strengths and gaps in the European research base. Methods A typology of nine research themes was developed, spanning food, society, health and research structures. Experts were selected through the FAHRE partners, with balance for individual characteristics, and reported using a standardised template. Results Countries usually commission research on food, and on health, separately: few countries have combined research strategies or programmes. Food and health are also strongly independent fields within the European Commission's research programmes. Research programmes have supported food and bio-technology, food safety, epidemiological research, and nutritional surveillance; but there has been less research into personal behaviour and very little on environmental influences on food choices - in the retail and marketing industries, policy, and regulation. The research is mainly sited within universities and research institutes: there is relatively little published research contribution from industry. Discussion National food policies, based on epidemiological evidence and endorsed by the World Health Organisation, recommend major changes in food intake to meet the challenge of chronic diseases. Biomedical and biotechnology research, in areas such as 'nutrio-genomics', 'individualised' diets, 'functional' foods and 'nutri-pharmaceuticals' appear likely to yield less health benefit, and less return on public investment, than research on population-level interventions

  18. Research for food and health in Europe: themes, needs and proposals.

    Science.gov (United States)

    McCarthy, Mark; Aitsi-Selmi, Amina; Bánáti, Diána; Frewer, Lynn; Hirani, Vasant; Lobstein, Tim; McKenna, Brian; Mulla, Zenab; Rabozzi, Giulia; Sfetcu, Raluca; Newton, Rachel

    2011-09-29

    Diet, in addition to tobacco, alcohol and physical exercise, is a major factor contributing to chronic diseases in Europe. There is a pressing need for multidisciplinary research to promote healthier food choices and better diets. Food and Health Research in Europe (FAHRE) is a collaborative project commissioned by the European Union. Among its tasks is the description of national research systems for food and health and, in work reported here, the identification of strengths and gaps in the European research base. A typology of nine research themes was developed, spanning food, society, health and research structures. Experts were selected through the FAHRE partners, with balance for individual characteristics, and reported using a standardised template. Countries usually commission research on food, and on health, separately: few countries have combined research strategies or programmes. Food and health are also strongly independent fields within the European Commission's research programmes. Research programmes have supported food and bio-technology, food safety, epidemiological research, and nutritional surveillance; but there has been less research into personal behaviour and very little on environmental influences on food choices - in the retail and marketing industries, policy, and regulation. The research is mainly sited within universities and research institutes: there is relatively little published research contribution from industry. National food policies, based on epidemiological evidence and endorsed by the World Health Organisation, recommend major changes in food intake to meet the challenge of chronic diseases. Biomedical and biotechnology research, in areas such as 'nutrio-genomics', 'individualised' diets, 'functional' foods and 'nutri-pharmaceuticals' appear likely to yield less health benefit, and less return on public investment, than research on population-level interventions to influence dietary patterns: for example policies to reduce

  19. Research for food and health in Europe: themes, needs and proposals

    Science.gov (United States)

    2011-01-01

    Background Diet, in addition to tobacco, alcohol and physical exercise, is a major factor contributing to chronic diseases in Europe. There is a pressing need for multidisciplinary research to promote healthier food choices and better diets. Food and Health Research in Europe (FAHRE) is a collaborative project commissioned by the European Union. Among its tasks is the description of national research systems for food and health and, in work reported here, the identification of strengths and gaps in the European research base. Methods A typology of nine research themes was developed, spanning food, society, health and research structures. Experts were selected through the FAHRE partners, with balance for individual characteristics, and reported using a standardised template. Results Countries usually commission research on food, and on health, separately: few countries have combined research strategies or programmes. Food and health are also strongly independent fields within the European Commission's research programmes. Research programmes have supported food and bio-technology, food safety, epidemiological research, and nutritional surveillance; but there has been less research into personal behaviour and very little on environmental influences on food choices - in the retail and marketing industries, policy, and regulation. The research is mainly sited within universities and research institutes: there is relatively little published research contribution from industry. Discussion National food policies, based on epidemiological evidence and endorsed by the World Health Organisation, recommend major changes in food intake to meet the challenge of chronic diseases. Biomedical and biotechnology research, in areas such as 'nutrio-genomics', 'individualised' diets, 'functional' foods and 'nutri-pharmaceuticals' appear likely to yield less health benefit, and less return on public investment, than research on population-level interventions to influence dietary

  20. Attitudes toward Tobacco, Alcohol, and Non-Alcoholic Beverage Advertisement Themes among Adolescent Boys.

    Science.gov (United States)

    Friedman, Katherine L; Roberts, Megan E; Keller-Hamilton, Brittney; Yates, Katherine A; Paskett, Electra D; Berman, Micah L; Slater, Michael D; Lu, Bo; Ferketich, Amy K

    2018-02-13

    Previous studies have examined what adolescents find appealing in tobacco and alcohol advertisements and how different themes in advertisements are used to manipulate consumer behaviors. Yet, we know little about the relationship between the themes portrayed in advertisements and youth attitudes towards those themes. This study compared attitudes towards advertisements for different consumer products in a sample of urban and rural adolescent boys in order to examine how key marketing themes impact adolescent attitudes towards those advertisements. Participants were 11- to 16-year-old boys (N = 1220) residing in either urban or rural Ohio Appalachian counties. Each participant viewed five print advertisements (one each for cigarettes, electronic cigarettes (e-cigarettes), smokeless tobacco (SLT), non-alcoholic beverages, and alcohol), presented in a random order, for eight seconds each. All advertisements had appeared in magazines that adolescent males commonly read. Attitudes towards each of the five advertisements were assessed. The advertisements were then coded for the presence of various themes, including social acceptance and masculinity. Analyses were conducted to determine associations between advertisement type and the attitude measure, and between the presence of a theme and the attitude measure. Overall, participants preferred non-tobacco advertisements to tobacco advertisements, rural participants had less positive attitudes and participants who had peers who used tobacco had more positive attitudes. Social acceptance and entertainment themes increased the appeal of SLT advertisements, and sex appeal increased the appeal of e-cigarette advertisements. Conclusions/Importance: Findings suggest that advertisements that promote the social nature of use in SLT advertisements may be of particular concern for their influence on adolescent boys.

  1. Nanomedicine-emerging or re-emerging ethical issues? A discussion of four ethical themes.

    Science.gov (United States)

    Lenk, Christian; Biller-Andorno, Nikola

    2007-06-01

    Nanomedicine plays a prominent role among emerging technologies. The spectrum of potential applications is as broad as it is promising. It includes the use of nanoparticles and nanodevices for diagnostics, targeted drug delivery in the human body, the production of new therapeutic materials as well as nanorobots or nanoprotheses. Funding agencies are investing large sums in the development of this area, among them the European Commission, which has launched a large network for life-sciences related nanotechnology. At the same time government agencies as well as the private sector are putting forward reports of working groups that have looked into the promises and risks of these developments. This paper will begin with an introduction to the central ethical themes as identified by selected reports from Europe and beyond. In a next step, it will analyse the most frequently invoked ethical concerns-risk assessment and management, the issues of human identity and enhancement, possible implications for civil liberties (e.g. nanodevices that might be used for covert surveillance), and concerns about equity and fair access. Although it seems that the main ethical issues are not unique to nanotechnologies, the conclusion will argue against shrugging them off as non-specific items that have been considered before in the context of other biomedical technologies, such as gene therapy or xenotransplantation. Rather, the paper will call on ethicists to help foster a rational, fair and participatory discourse on the different potential applications of nanotechnologies in medicine, which can form the basis for informed and responsible societal and political decisions.

  2. Effects of marital conflict on children: recent advances and emerging themes in process-oriented research.

    Science.gov (United States)

    Cummings, E Mark; Davies, Patrick T

    2002-01-01

    The effects of marital conflict on children's adjustment are well documented. For the past decade research has increasingly focused on advancing a process-level understanding of these effects, that is, accounting for the particular responses and patterns embedded within specific contexts, histories, and developmental periods that account for children's outcomes over time. As a vehicle for presenting an update, this review follows the framework for process-oriented research initially proposed by Cummings and Cummings (1988), concentrating on recent research developments, and also considering new and emerging themes in this area of research. In this regard, areas of advancement include (a) greater articulation of the effects of specific context/stimulus characteristics of marital conflict, (b) progress in identifying the psychological response processes in children (e.g., cognitive, emotional, social, physiological) that are affected and their possible role in accounting for relations between marital conflict and child outcomes, (c) greater understanding of the role of child characteristics, family history, and other contextual factors, including effects on children due to interrelations between marital conflict and parenting, and (d) advances in the conceptualization of children's outcomes, including that effects may be more productively viewed as dynamic processes of functioning rather than simply clinical diagnoses. Understanding of the impact of marital conflict on children as a function of time-related processes remains a gap in a process-oriented conceptualization of effects. Based on this review, a revised model for a process-oriented approach on the effects of marital discord on children is proposed and suggestions are made for future research directions.

  3. Major Sport Venues

    Data.gov (United States)

    Department of Homeland Security — The Major Public Venues dataset is composed of facilities that host events for the National Association for Stock Car Auto Racing, Indy Racing League, Major League...

  4. Major Depression Among Adults

    Science.gov (United States)

    ... Depressive Episode Among Adolescents Data Sources Share Major Depression Definitions Major depression is one of the most ... Bethesda, MD 20892-9663 Follow Us Facebook Twitter YouTube Google Plus NIMH Newsletter NIMH RSS Feed NIMH ...

  5. Tourism-themed internet portals – are new media creating a new tourist? A case study of Polish students

    Directory of Open Access Journals (Sweden)

    Jażdżewska Iwona

    2017-03-01

    Full Text Available Internet media have an influence on many tourism-related issues. This article presents the results of research into the role of tourism-themed portals in the trips taken by Polish university students between 2010 and 2012. The research sought to answer the following questions: whether tourism-related internet media have an influence on the students’ behaviour before, during the trip and when they arrive at their destination; how often they are used by the respondents during their trips; and whether Polish students actively participate in internet media by voicing their opinions. As it appears, internet media serve as one of the “travel companions” for young people. They are used when preparing the trip, the vast majority “take them” with them and check them during the trip, while almost half of them check them on vacation, e.g. to share their experience over the internet.

  6. Mathematical Communication Ability by Grade VII Students Using a Themed Problem Based Learning with Scaffolding on Rectangle Materials

    Directory of Open Access Journals (Sweden)

    Didik Adi Saputro

    2017-08-01

    Full Text Available The aim of research to test students' mathematical communication used themed of PBL with scaffolding, themed of PBL and PBL achieve mastery learning;to test students' mathematical communication that used the themed of PBL with scaffolding, themed of PBL and PBL; and to test students' mathematical communication for the low, medium group, and a high-group themed of PBL with scaffolding, themed of PBL and PBL. This type of research is quantitative research. The Population is seventh grade students of SMPN 22 Semarang and the sample class VII E, F and VII VII G. Used normality test, homogenity test, equality test on average, the proportion of one-party test, one way anova test, and scheffe test. The results showed that (1 Student’s mathematical communication ability using themed of PBLwith Scaffolding strategy,themed of PBL, and PBL achieve the completeness of learning, (2 there is a difference in the classroom using the themed of PBL with scaffolding, themed of PBL, as well as PBL, (3 For the low, medium, high and there is a difference in the classroom using the themed of PBL with scaffolding, themed of PBL and PBL.

  7. Assessment report on NRP sub-theme 'International instruments for climate change policy'

    International Nuclear Information System (INIS)

    Bruggink, J.J.C.; Van Beek, P.; Folmer, H.; Zhang, Z.X.; Blok, K.; Phylipsen, D.; Worrell, E.; Gupta, J.; Junne, G.; Van der Wurff, R.

    1995-01-01

    The projects implemented in the Dutch National Research Programme on Global Air Pollution and Climate Change are organised in several themes and sub-themes. Within the theme on Sustainable Solutions five projects are grouped under the heading International Instruments for Climate Change Policy. These five projects deal primarily with issues concerning the position of developing countries in the debate on limiting global CO2-emissions. They cover a broad spectrum of topics: international negotiation strategies, tropical deforestation, industrial energy conservation, national energy scenarios, emission guidelines. This contribution presents an overview of the objectives, methodologies and results of the projects and includes a critical evaluation of the potential relevance of the work for policy makers. 1 tab., 36 refs

  8. Making Sense of the Brutality of the Holocaust: Critical Themes and New Perspectives.

    Science.gov (United States)

    Miller, Eric D

    2017-01-02

    This article offers an analytic, integrative review of select themes associated with one of history's greatest atrocities: the Holocaust. Much of this review considers general and Holocaust-specific themes as they pertain to the nature of senseless violence and evil. The importance of having a greater understanding of the sheer brutality of violence perpetuated in the Holocaust is emphasized. As part of this discussion, considerable attention is given to how Internet-based photographs and videos from the Holocaust era can provide greater insight into understanding the evil associated with this genocide. Some consideration of the larger meaning of the Holocaust, particularly for Jews, is also examined.

  9. Major depressive disorder: a qualitative study on the experiences of Iranian patients.

    Science.gov (United States)

    Amini, Kourosh; Negarandeh, Reza; Cheraghi, Mohammad Ali; Eftekhar, Mehrdad

    2013-09-01

    Major depressive disorder (MDD) is one the most common mental disorders; it affects about 5-10% of the world population. This study explores the experiences of people with major depressive disorder in Zanjan, Iran. In order to identify recurring themes and patterns in individuals' experiences of major depressive disorder, semi-structured interviews with 18 patients were recorded and transcribed verbatim. The transcripts were then analyzed based on conventional qualitative content analysis. Five main categories emerged. The first category was called emotional paralysis and included the subcategories feeling severely depressed; feeling anxious; feeling impatient and irritable; and having dyshedonia. The second category was disturbance of thinking and was comprised of the subcategories of preoccupation, instable spiritual beliefs, and guilt. Cognitive decline was the third identified category and was further divided into subcategories of frustration, unawareness of the disorder, negative evaluation, indecisiveness, and loss of focus and loss of memory. Another major category was physical illnesses with the subcategories of physical discomfort, sleep problems, appetite disturbance, facial changes, sexual dysfunction, and medical conditions. The final category was failure in life, which had failure in personal affairs, jeopardized interpersonal relations, and unstable work life as subcategories. These findings provide a base for further research in this area. They also have clinical relevance for health care providers working with patients with MDD. Related cultural issues also are discussed.

  10. 75 FR 31383 - Major Capital Investment Projects

    Science.gov (United States)

    2010-06-03

    ...-0009] RIN 2132-AB02 Major Capital Investment Projects AGENCIES: Federal Transit Administration (FTA... current approach to evaluating and rating major capital investment projects (``New Starts'' and ``Small...'' to address identified transportation needs in the corridor without a major capital investment in new...

  11. Current Themes in Understanding Children’s Emotion Regulation as Developing from within the Parent-Child Relationship

    Science.gov (United States)

    Kiel, Elizabeth J.; Kalomiris, Anne E.

    2015-01-01

    A large existing literature has established that children’s emotion regulation (ER) behaviors and capacities emerge from within the parent-child relationship. This review identified very recently published studies that exemplify contemporary themes in this area of research. Specifically, new research suggests that the influence of fathers, above and beyond that of mothers, becomes more pronounced across development. Further, culture influences how parents socialize emotion and how specific parenting behaviors relate to children’s developing ER. Lastly, studies find child-elicited effects, such that children’s ER predicts parents’ emotion socialization and other relevant behaviors. We suggest several future directions, including understanding the nature of situations that elicit ER patterns, as well as both expanding upon and integrating the areas highlighted in the review. PMID:25745639

  12. Elementary School Teachers' Perceptions Regarding the Inclusion of LGBTQ Themed Literature

    Science.gov (United States)

    Grasso, Dominic

    2016-01-01

    This critical explanatory mixed methods study examined elementary teachers' perceptions regarding the inclusion of LGBTQ-themed literature in the curriculum. An electronic survey questionnaire and focus group sessions were used to collect both quantitative and qualitative data that described the perceived benefits and barriers of LGBTQ-themed…

  13. the theme of democracy in the drama of ola rotimi and wole soyinka

    African Journals Online (AJOL)

    The preoccupation of this study is to critically examine the theme of democracy in Ola Rotimi's Our Husband has Gone Mad Again: a comedy and Wole Soyinka's Kongi's Harvest. Our choice of Rotimi and Soyinka is based on the fact that both of them rank toweringly among the most accomplished playwrights and theatre ...

  14. Food as a Theme in Social Studies Classes: Connecting Daily Life to Technology, Economy, and Culture

    Science.gov (United States)

    Resor, Cynthia Williams

    2010-01-01

    Connecting wider economic, technological, or cultural trends to the everyday life of students can be a challenge. Food can serve as a course-long theme that helps students comprehend the essential connection between personal actions and national or international trends and develop skills of critical analysis. The author describes four activities…

  15. Theme-Based Courses Foster Student Learning and Promote Comfort with Learning New Material

    Science.gov (United States)

    Tessier, Lisa; Tessier, Jack

    2015-01-01

    In this article, we review the literature about theme-based teaching, then report quantitative and qualitative results from surveys from three different courses: one section of a 100-level in-person art course; five sections of 300-level on-line art courses; and one section of a 100-level in-person biology course at SUNY Delhi with applied themes…

  16. Themes, scenes, and taste in the history of Japanese garden art

    NARCIS (Netherlands)

    Kuitert, W.

    1988-01-01

    The present study deals - in its three parts - with three fragments of the garden history of Japan. It reveals how the meaning a garden had to the people of its time was significantly different in all of these periods.

    Part one, titled "Themes", deals with the later Heian period,

  17. Interviewing to assess credibility in the Swedish asylum procedure: analyzing question style, type and theme

    NARCIS (Netherlands)

    van Veldhuizen, T.S.; Horselenberg, R.; Landström, S.; Granhag, P.A.; van Koppen, P.J.

    2017-01-01

    The aim of the current vignette study is to map the style, type, and themes of questions that are asked when assessing the credibility of asylum seekers' claims. Sixty-five officials from the Swedish Migration Agency (Migrationsverket), were asked to respond to one out of four different vignettes

  18. Simulations, Imaging, and Modeling: A Unique Theme for an Undergraduate Research Program in Biomechanics.

    Science.gov (United States)

    George, Stephanie M; Domire, Zachary J

    2017-07-01

    As the reliance on computational models to inform experiments and evaluate medical devices grows, the demand for students with modeling experience will grow. In this paper, we report on the 3-yr experience of a National Science Foundation (NSF) funded Research Experiences for Undergraduates (REU) based on the theme simulations, imaging, and modeling in biomechanics. While directly applicable to REU sites, our findings also apply to those creating other types of summer undergraduate research programs. The objective of the paper is to examine if a theme of simulations, imaging, and modeling will improve students' understanding of the important topic of modeling, provide an overall positive research experience, and provide an interdisciplinary experience. The structure of the program and the evaluation plan are described. We report on the results from 25 students over three summers from 2014 to 2016. Overall, students reported significant gains in the knowledge of modeling, research process, and graduate school based on self-reported mastery levels and open-ended qualitative responses. This theme provides students with a skill set that is adaptable to other applications illustrating the interdisciplinary nature of modeling in biomechanics. Another advantage is that students may also be able to continue working on their project following the summer experience through network connections. In conclusion, we have described the successful implementation of the theme simulation, imaging, and modeling for an REU site and the overall positive response of the student participants.

  19. Being in Community: A Food Security Themed Approach to Public Scholarship

    Science.gov (United States)

    Harrison, Barbara; Nelson, Connie; Stroink, Mirella

    2013-01-01

    For six years the Food Security Research Network at Lakehead University, Canada, has been engaged in an interdisciplinary theme-based service-learning initiative focusing on food security. Informed by complexity theory, the contextual fluidity partnership model brings community partners, students, and faculty into a nexus through which new…

  20. Conservation of Life as a Unifying Theme for Process Safety in Chemical Engineering Education

    Science.gov (United States)

    Klein, James A.; Davis, Richard A.

    2011-01-01

    This paper explores the use of "conservation of life" as a concept and unifying theme for increasing awareness, application, and integration of process safety in chemical engineering education. Students need to think of conservation of mass, conservation of energy, and conservation of life as equally important in engineering design and analysis.…

  1. Children's Violently Themed Play and Adult Imaginaries of Childhood: A Bakhtinian Analysis

    Science.gov (United States)

    Rosen, Rachel

    2015-01-01

    Children's violently themed play has long been contentious within educational policy, parenting literature, and the academe, with conflicting views as to its immediate and long-term consequences. Yet, little attention has been given to the way in which the meanings and values attributed to childhood influence these debates. Drawing on an…

  2. The Relationship between Kolb's Learning Styles and StrengthsFinder's Talent Themes

    Science.gov (United States)

    Caldwell, Adonna B.

    2009-01-01

    The purpose of this study was to investigate if there were relationships between college students' talent themes as defined by the Clifton StrengthsFinder(TM) Instrument and their learning style as defined by Kolb Learning Styles Inventory. Logistical regression methodology was utilized to assess the relationship between learning styles and talent…

  3. A wavelet-based approach to the discovery of themes and sections in monophonic melodies

    DEFF Research Database (Denmark)

    Velarde, Gissel; Meredith, David

    We present the computational method submitted to the MIREX 2014 Discovery of Repeated Themes & Sections task, and the results on the monophonic version of the JKU Patterns Development Database. In the context of pattern discovery in monophonic music, the idea behind our method is that, with a good...

  4. Dumb Dorky Girls and Wimpy Boys: Gendered Themes in Diary Cartoon Novels

    Science.gov (United States)

    Taber, Nancy; Woloshyn, Vera

    2011-01-01

    In this paper, we focus on gendered themes promulgated in three books written in diary cartoon form. Although written for different audiences, each of these books constructs gender norms in similar ways. They promote heteronormative gender roles for boys and girls by endorsing traditional femininities and hegemonic masculinities through the…

  5. Refugee-Themed Picture Books for Ethical Understanding in Curriculum English

    Science.gov (United States)

    Dooley, Karen; Tait, Gordon; Zabarjadi Sar, Hora

    2016-01-01

    This study looked at the curricular resource potential of refugee-themed picture books for embedding an ethics of responsibility for linguistic diversity into the subject of English studied by all students in English-dominant western societies. Selected picture books were analysed in terms of a Levinasean ethics of responsibility for alterity in…

  6. Looking to the Future: Themes from the Third National Conference for Counseling Psychology.

    Science.gov (United States)

    Rude, Stephanie S.; And Others

    1988-01-01

    Presents summary of common themes from the Third National Conference for Counseling Psychology including strategies to enhance visibility and political strength, and ways to improve training of counseling psychologists by enhancing rigor, scientific thinking, professional identity, and ability to work in diverse and emerging settings. Discusses…

  7. Simple webs of natural environment theme as a result of sharing in science teacher training

    Science.gov (United States)

    Tapilouw, M. C.; Firman, H.; Redjeki, S.; Chandra, D. T.

    2018-03-01

    Thematic learning is one type of integrated science (Biology, Physics, Chemistry and Earth Science) in Science Education. This study is concerning about simple webs of natural environment theme in science learning, as one of training material in science teacher training program. Making simple web is a goal of first step in teacher training program. Every group explain their web illustration to other group. Twenty Junior High School science teacher above one education foundation participate in science teacher training program. In order to gather simple webs, sharing method was used in this first step of science teacher training. The result of this study is five different simple web of natural environment themes. These webs represent science learning in class VII/Semester I, class VII/Semester II, Class VIII, Class IX/Semester I, Class IX/Semester II based on basic competency in National Curriculum 2013. Each group discussed web of natural environment theme based on their learning experience in real class which basic competency and subject matters are linked with natural environment theme. As a conclusion, simple webs are potential to develop in the next step of science teacher training program and to be implemented in real class.

  8. Theme issue on e-Mental health: a growing field in internet research: Editorial.

    NARCIS (Netherlands)

    Riper, H.; Andersson, G.; Christensen, H.; Cuijpers, P.; Lange, A.; Eysenbach, G.

    2010-01-01

    This theme issue on e-mental health presents 16 articles from leading researchers working on systems and theories related to supporting and improving mental health conditions and mental health care using information and communication technologies. In this editorial, we present the background of this

  9. Theme issue on e-mental health: a growing field in internet research

    NARCIS (Netherlands)

    Riper, H.; Andersson, G.; Christensen, H.; Cuijpers, P.; Lange, A; Eysenbach, G

    2010-01-01

    This theme issue on e-mental health presents 16 articles from leading researchers working on systems and theories related to supporting and improving mental health conditions and mental health care using information and communication technologies. In this editorial, we present the background of this

  10. The Hot and Energetic Universe: A White Paper presenting the science theme motivating the Athena+ mission

    NARCIS (Netherlands)

    Nandra, Kirpal; Barret, Didier; Barcons, Xavier; Fabian, Andy; den Herder, Jan-Willem; Piro, Luigi; Watson, Mike; Adami, Christophe; Aird, James; Afonso, Jose Manuel; Alexander, Dave; Argiroffi, Costanza; Amati, Lorenzo; Arnaud, Monique; Atteia, Jean-Luc; Audard, Marc; Badenes, Carles; Ballet, Jean; Ballo, Lucia; Bamba, Aya; Bhardwaj, Anil; Stefano Battistelli, Elia; Becker, Werner; De Becker, Michaël; Behar, Ehud; Bianchi, Stefano; Biffi, Veronica; Bîrzan, Laura; Bocchino, Fabrizio; Bogdanov, Slavko; Boirin, Laurence; Boller, Thomas; Borgani, Stefano; Borm, Katharina; Bouché, Nicolas; Bourdin, Hervé; Bower, Richard; Braito, Valentina; Branchini, Enzo; Branduardi-Raymont, Graziella; Bregman, Joel; Brenneman, Laura; Brightman, Murray; Brüggen, Marcus; Buchner, Johannes; Bulbul, Esra; Brusa, Marcella; Bursa, Michal; Caccianiga, Alessandro; Cackett, Ed; Campana, Sergio; Cappelluti, Nico; Cappi, Massimo; Carrera, Francisco; Ceballos, Maite; Christensen, Finn; Chu, You-Hua; Churazov, Eugene; Clerc, Nicolas; Corbel, Stephane; Corral, Amalia; Comastri, Andrea; Costantini, Elisa; Croston, Judith; Dadina, Mauro; D'Ai, Antonino; Decourchelle, Anne; Della Ceca, Roberto; Dennerl, Konrad; Dolag, Klaus; Done, Chris; Dovciak, Michal; Drake, Jeremy; Eckert, Dominique; Edge, Alastair; Ettori, Stefano; Ezoe, Yuichiro; Feigelson, Eric; Fender, Rob; Feruglio, Chiara; Finoguenov, Alexis; Fiore, Fabrizio; Galeazzi, Massimiliano; Gallagher, Sarah; Gandhi, Poshak; Gaspari, Massimo; Gastaldello, Fabio; Georgakakis, Antonis; Georgantopoulos, Ioannis; Gilfanov, Marat; Gitti, Myriam; Gladstone, Randy; Goosmann, Rene; Gosset, Eric; Grosso, Nicolas; Guedel, Manuel; Guerrero, Martin; Haberl, Frank; Hardcastle, Martin; Heinz, Sebastian; Alonso Herrero, Almudena; Hervé, Anthony; Holmstrom, Mats; Iwasawa, Kazushi; Jonker, Peter; Kaastra, Jelle; Kara, Erin; Karas, Vladimir; Kastner, Joel; King, Andrew; Kosenko, Daria; Koutroumpa, Dimita; Kraft, Ralph; Kreykenbohm, Ingo; Lallement, Rosine; Lanzuisi, Giorgio; Lee, J.; Lemoine-Goumard, Marianne; Lobban, Andrew; Lodato, Giuseppe; Lovisari, Lorenzo; Lotti, Simone; McCharthy, Ian; McNamara, Brian; Maggio, Antonio; Maiolino, Roberto; De Marco, Barbara; de Martino, Domitilla; Mateos, Silvia; Matt, Giorgio; Maughan, Ben; Mazzotta, Pasquale; Mendez, Mariano; Merloni, Andrea; Micela, Giuseppina; Miceli, Marco; Mignani, Robert; Miller, Jon; Miniutti, Giovanni; Molendi, Silvano; Montez, Rodolfo; Moretti, Alberto; Motch, Christian; Nazé, Yaël; Nevalainen, Jukka; Nicastro, Fabrizio; Nulsen, Paul; Ohashi, Takaya; O'Brien, Paul; Osborne, Julian; Oskinova, Lida; Pacaud, Florian; Paerels, Frederik; Page, Mat; Papadakis, Iossif; Pareschi, Giovanni; Petre, Robert; Petrucci, Pierre-Olivier; Piconcelli, Enrico; Pillitteri, Ignazio; Pinto, C.; de Plaa, Jelle; Pointecouteau, Etienne; Ponman, Trevor; Ponti, Gabriele; Porquet, Delphine; Pounds, Ken; Pratt, Gabriel; Predehl, Peter; Proga, Daniel; Psaltis, Dimitrios; Rafferty, David; Ramos-Ceja, Miriam; Ranalli, Piero; Rasia, Elena; Rau, Arne; Rauw, Gregor; Rea, Nanda; Read, Andy; Reeves, James; Reiprich, Thomas; Renaud, Matthieu; Reynolds, Chris; Risaliti, Guido; Rodriguez, Jerome; Rodriguez Hidalgo, Paola; Roncarelli, Mauro; Rosario, David; Rossetti, Mariachiara; Rozanska, Agata; Rovilos, Emmanouil; Salvaterra, Ruben; Salvato, Mara; Di Salvo, Tiziana; Sanders, Jeremy; Sanz-Forcada, Jorge; Schawinski, Kevin; Schaye, Joop; Schwope, Axel; Sciortino, Salvatore; Severgnini, Paola; Shankar, Francesco; Sijacki, Debora; Sim, Stuart; Schmid, Christian; Smith, Randall; Steiner, Andrew; Stelzer, Beate; Stewart, Gordon; Strohmayer, Tod; Strüder, Lothar; Sun, Ming; Takei, Yoh; Tatischeff, V.; Tiengo, Andreas; Tombesi, Francesco; Trinchieri, Ginevra; Tsuru, T. G.; Ud-Doula, Asif; Ursino, Eugenio; Valencic, Lynne; Vanzella, Eros; Vaughan, Simon; Vignali, Cristian; Vink, Jacco; Vito, Fabio; Volonteri, Marta; Wang, Daniel; Webb, Natalie; Willingale, Richard; Wilms, Joern; Wise, Michael; Worrall, Diana; Young, Andrew; Zampieri, Luca; In't Zand, Jean; Zane, Silvia; Zezas, Andreas; Zhang, Yuying; Zhuravleva, Irina

    2013-01-01

    This White Paper, submitted to the recent ESA call for science themes to define its future large missions, advocates the need for a transformational leap in our understanding of two key questions in astrophysics: 1) How does ordinary matter assemble into the large scale structures that we see today?

  11. Waiting as Part of the Fun: Interactive Gaming in Theme Park Queues

    NARCIS (Netherlands)

    Heger, Chris; Offermans, S.A.M.; Frens, J.W.; Wouters, I.H.C.; Kimman, F.P.F.; Tieben, R.; Offermans, S.A.M.; Nagtzaam, H.A.H.

    2009-01-01

    People visiting theme parks intend to have a day of fun. Yet a larger part of the time is spent queuing for rides rather than in the actual rides, which does not contribute to the intended fun experience. Current efforts therefore either make the queue as bearable as possible or try to get rid of it

  12. M-Learning Challenges in Teaching Crosscutting Themes in the Education of Young People and Adults

    Science.gov (United States)

    Ota, Marcos Andrei; de Araujo, Carlos Fernando, Jr.

    2016-01-01

    The challenges faced in using new technologies in the classroom are numerous, but contributions generated with their resolution can proportionately provide original and efficient teaching practices more in tune to students' eager learning needs. This article presents some strategies developed to help teachers in transversal themes classes using…

  13. An Exploration of Adlerian Lifestyle Themes and Alcohol-Related Behaviors among College Students

    Science.gov (United States)

    Lewis, Todd F.; Osborn, Cynthia J.

    2004-01-01

    The aim of this study was to investigate college student drinking through the lens of Adlerian theory. In a sample of 273 participants, multiple regression analyses confirmed that certain lifestyle themes were associated with alcohol-related behaviors and that men and women who engage in drinking differ in their convictions and goals as defined by…

  14. Theme 2 Overview: Making a Living, Training, Trade and Investment in the Circumpolar North.

    Science.gov (United States)

    McLeod, Bob

    1998-01-01

    An intergovernmental council on sustainable development in the Arctic discussed fisheries, wildlife, forestry, mining, oil and gas, tourism, finance and marketing, communication and education, and youth initiatives. Emerging themes included community involvement in decision making, acknowledging indigenous peoples' rights and knowledge,…

  15. e-Business challenges and directions: important themes from the first ICE-B workshop

    NARCIS (Netherlands)

    Marca, David; Bulander, Rebecca; Kruslin, Cornelia; Shishkov, Boris; van Sinderen, Marten J.; Obaidat, Mohammad S.; Tsihrintzis, George A.; Filipe, Joaquim

    2012-01-01

    A three-day asynchronous, interactive workshop was held at ICE-B’10 in Piraeus, Greece in July of 2010. This event captured conference themes for e-Business challenges and directions across four subject areas: a) e-Business applications and models, b) enterprise engineering, c) mobility, d) business

  16. Regional Themes and Global Means in Supra-National Higher Education Policy

    Science.gov (United States)

    Watson, Pam

    2009-01-01

    The supra-national level has become increasingly important in educational policy formulation. This paper describes and compares two settings in which growth in these supra-national policies is evident--in Europe and in Africa. Key themes arising in policy documents in each context are examined. A distinction is drawn in analysis between themes…

  17. (Text) Mining the LANDscape: Themes and Trends over 40 years of Landscape and Urban Planning

    Science.gov (United States)

    Paul H. Gobster

    2014-01-01

    In commemoration of the journal's 40th anniversary, the co-editor explores themes and trends covered by Landscape and Urban Planning and its parent journals through a qualitative comparison of co-occurrence term maps generated from the text corpora of its abstracts across the four decadal periods of publication.Cluster maps generated from the...

  18. "Teachosaurus" and "Learnoceratops": Dinosaurs as a Motivating Cross-Curricular Theme

    Science.gov (United States)

    Duggan, Denis

    2011-01-01

    The author takes a look into the benefits that dinosaurs may bring to the classroom. He discusses how he used dinosaurs as a cross-curricular theme to improve children's understanding and knowledge of science concepts. To investigate what a child might learn from dinosaurs, he started by comparing the many non-fiction dinosaur books using the…

  19. Mission 2 Solution: Requirements Engineering Education as a Central Theme in the BIT Programme

    NARCIS (Netherlands)

    Huijs, C.; Sikkel, Nicolaas; Wieringa, Roelf J.

    Design of integrated business-IT solutions is the main theme in the Business Information Technology programme (BIT) at the University of Twente. Our mission is to teach students to design solutions that are needed instead of solutions that are asked for. This makes requirements engineering an

  20. Theme-Based Project Learning: Design and Application of Convergent Science Experiments

    Science.gov (United States)

    Chun, Man-Seog; Kang, Kwang Il; Kim, Young H.; Kim, Young Mee

    2015-01-01

    This case study aims to verify the benefits of theme-based project learning for convergent science experiments. The study explores the possibilities of enhancing creative, integrated and collaborative teaching and learning abilities in science-gifted education. A convergent project-based science experiment program of physics, chemistry and biology…

  1. A Theme-Based Course: Hydrogen as the Fuel of the Future

    Science.gov (United States)

    Shultz, Mary Jane; Kelly, Matthew; Paritsky, Leonid; Wagner, Julia

    2009-01-01

    A theme-based course focusing on the potential role of hydrogen as a future fuel is described. Numerous topics included in typical introductory courses can be directly related to the issue of hydrogen energy. Beginning topics include Avogadro's number, the mole, atomic mass, gas laws, and the role of electrons in chemical transformations. Reaction…

  2. Hopping into Economics: First Graders Learn about Economics through an Easter Theme.

    Science.gov (United States)

    Davis, Gaylene

    A 3-month study unit introducing first grade students to economics through an Easter theme is outlined in five sections. Sections 1 and 2 describe rationale, goals, and learning objectives. Section 3 provides learning activities. A wide range of instructional strategies is used to teach the basic economic concepts of want, need, scarcity,…

  3. Opening Doors: Teaching LGBTQ-Themed Young Adult Literature for an Inclusive Curriculum

    Science.gov (United States)

    Batchelor, Katherine E.; Ramos, Maria; Neiswander, Samantha

    2018-01-01

    LGBTQ themes are often neglected in many schools' curriculum. Currently, an LGBTQ-inclusive curriculum framework is not required in most school districts across the county. Therefore, it is important to understand how teachers regard LGBTQ issues; how they address the needs of students in the middle school and high school English classroom who…

  4. Complexity: Outline of the NWO strategic theme Dynamics of complex systems

    NARCIS (Netherlands)

    Burgers, G.; Doelman, A.; Frenken, K.; Hogeweg, P.; Hommes, C.; van der Maas, H.; Mulder, B.; Stam, K.; van Steen, M.; Zandee, L.

    2008-01-01

    Dynamics of complex systems is one of the program 5 themes in the NWO (Netherlands Organisation for Scientific Research) strategy for the years 2007-2011. The ambition of the current proposal is to initiate integrated activities in the field of complex systems within the Netherlands, to provide

  5. Complexity : outline of the NWO strategic theme dynamics of complex systems

    NARCIS (Netherlands)

    Burgers, G.; Doelman, A.; Frenken, K.; Hogeweg, P.; Hommes, C.; Maas, van der H.; Mulder, B.; Stam, K.; Steen, van M.; Zandee, L.

    2008-01-01

    Dynamics of complex systems is one of the program 5 themes in the NWO (Netherlands Organisation for Scientific Research) strategy for the years 2007-2011. The ambition of the current proposal is to initiate integrated activities in the field of complex systems within the Netherlands, to provide

  6. Emerging synthesis themes from the study of social-ecological systems of a tropical city

    Science.gov (United States)

    Tischa A. Munoz; A.E. Lugo; B. Quintero

    2014-01-01

    The synthesis of the contributions in this special issue about the tropical city of San Juan has resulted in five themes. First, the city is subject to multiple vulnerabilities, but socioeconomic factors and education level affect the perception of citizens to those vulnerabilities, even in the face of imminent threat. Second, in light of the social-ecological...

  7. 'So Far, So Good...?' : Reflections on the Theme of 2017's Annual Workshop

    NARCIS (Netherlands)

    Joyce, F.; de Dijn, A.; Gribaldo, A.; Loader, I.; Lobina, E.; Moeller, N.; Overeem, P.; Pratt, M.; Rainsborough, J.; Stewart, C.; Wiggan, J.; Stroschein, S.; Symonds, J.; Ziemer, H.

    2017-01-01

    Why is the future a topic for social science? Why was it one for the ISRF’s 2017 Annual Workshop? The theme answers to the focus of the ISRF on ‘real-life’ problems; the ones we have now, and the ones we might encounter in the future having all too often brought them upon ourselves. As we tell our

  8. Identifying the Components of Effective Learning Environments Based on Health Students\\' Perception

    Directory of Open Access Journals (Sweden)

    Yousefi Afrashteh M

    2015-08-01

    Full Text Available Aims: Effective learning environment can lead to establish and strengthen the appropriate conditions of learning in higher education. This study aimed to identify and define the factors associated with effective learning environment in the field of health education. Participants & Methods: This qualitative study with content analysis approach was conducted in 2013. Participants were 9 graduate and 7 undergraduate students of health majors that were selected using purposive sampling method. Data were recorded by interview and were analyzed using qualitative content analysis. Findings: Analysis of the data revealed 4 themes and 13 classes active and interactive teaching (participating viewpoints of students in educational planning, engaging students in class discussions, providing practical examples to understand the content, relaxing about expressed thoughts, the possibility of constructive criticism master plan of activities and according to the conditions and individual differences between students, Joyful atmosphere (academic motivation, the joy of learning and attendance, a sense of acceptance and respect from teachers and classroom dynamics and vitality and fatigue, relation of courses with professional needs (knowledge of the needs of the job in training course content and related training to the needs of job opportunities and professors’ scientific and power and expert (expertise and scientific capabilities in the field of teaching. Conclusion: 4 major themes and their characteristics can help to organize the learning environment in medical education.

  9. A qualitative study of tobacco interventions for LGBTQ+ youth and young adults: overarching themes and key learnings.

    Science.gov (United States)

    Bruce Baskerville, N; Wong, Katy; Shuh, Alanna; Abramowicz, Aneta; Dash, Darly; Esmail, Aamer; Kennedy, Ryan

    2018-01-18

    Smoking prevalence is very high among lesbian, gay, bisexual, transgendered and queer (LGBTQ+) youth and young adults (YYA) compared to non-LGBTQ+ YYA. A knowledge gap exists on culturally appropriate and effective prevention and cessation efforts for members of this diverse community, as limited interventions have been developed with and for this population, and there are very few studies determining the impact of these interventions. This study identifies the most salient elements of LGBTQ+ cessation and prevention interventions from the perspective of LGBTQ+ YYA. Three descriptions of interventions tailored for LGBTQ+ YYA (group cessation counselling, social marketing, and a mobile phone app with social media incorporated), were shared with LGBTQ+ YYA via 24 focus groups with 204 participants in Toronto and Ottawa, Canada. Open-ended questions focused on their feelings, likes and dislikes, and concerns about the culturally modified intervention descriptions. Framework analysis was used to identify overarching themes across all three intervention descriptions. The data revealed eight overarching themes across all three intervention descriptions. Smoking cessation and prevention interventions should have the following key attributes: 1) be LGBTQ+ - specific; 2) be accessible in terms of location, time, availability, and cost; 3) be inclusive, relatable, and highlight diversity; 4) incorporate LGBTQ+ peer support and counselling services; 5) integrate other activities beyond smoking; 6) be positive, motivational, uplifting, and empowering; 7) provide concrete coping mechanisms; and 8) integrate rewards and incentives. LGBTQ+ YYA focus group participants expressed a desire for an intervention that can incorporate these key elements. The mobile phone app and social media campaign were noted as potential interventions that could include all the essential elements.

  10. Prospects after Major Trauma

    NARCIS (Netherlands)

    Holtslag, H.R.

    2007-01-01

    Introduction. After patients survived major trauma, their prospects, in terms of the consequences for functioning, are uncertain, which may impact severely on patient, family and society. The studies in this thesis describes the long-term outcomes of severe injured patients after major trauma. In

  11. Exploring the undergraduate experience of Latina students in Science, Technology, Engineering, and Mathematics (STEM) majors: Motivators and strategies for achieving baccalaureate attainment

    Science.gov (United States)

    Carbajal, Sandy C.

    Drawing from Latino/a Critical Race Theory and the related Community Cultural Wealth (CCW) model, I concentrate on three forms of CCW---aspirational, navigational, and resistance capital---for this qualitative study on the undergraduate experience of Latina students in Science, Technology, Engineering, and Mathematics (STEM) majors, focusing on strategies and achieving baccalaureate attainment. I interviewed ten Latina students and asked them questions regarding their educational experiences in STEM majors, what contributed to their degree completion, and the strategies they employed for achieving baccalaureate attainment. I identified and described six themes within the study (the underrepresentation of Latinas in STEM majors, the lack of preparation by academic programs for upper division courses, motivators, involvement, time management, and support networks) that, when combined, contributed to participants' degree attainment. This study concludes with implications for policy and practice that would allow universities to better assist Latinas in STEM majors to achieve baccalaureate attainment.

  12. Community Engagement for Identifying Cancer Education Needs in Puerto Rico.

    Science.gov (United States)

    Jiménez, Julio; Ramos, Axel; Ramos-Rivera, Francisco E; Gwede, Clement; Quinn, Gwendolyn P; Vadaparampil, Susan; Brandon, Thomas; Simmons, Vani; Castro, Eida

    2018-02-01

    Cancer is the leading cause of death in Puerto Rico, suggesting a need for improved strategies, programs, and resources devoted to cancer prevention. Enhanced prevention needs in Puerto Rico were initially identified in pilot studies conducted by the Ponce School of Medicine (PSM) in collaboration with the H. Lee Moffitt Cancer Center (MCC). In the current study, we used community engagement to identify specific needs in cancer prevention and education and strategies to create culturally attuned, effective cancer prevention education programs. A total of 37 participants attended a community forum and were assigned to one of three discussion groups: patients/survivors (n = 14); family/caregivers (n = 11); or healthcare providers (n = 12). Most participants were women (73 %), over 35 years of age, and a majority were married (58 %) and had a university education (81 %). The sessions were recorded and transcribed and analyzed for key themes. Participants wanted improved awareness of cancer prevention in Puerto Rico and believed cancer prevention education should start early, ideally in elementary school. Participants also stressed the importance of creating partnerships with private and government agencies to coordinate educational efforts. Suggested strategies included outreach to communities with limited resources, incorporating the testimony of cancer survivors, and utilizing social media to disseminate cancer prevention information.

  13. Major operations and activities

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the major operations and activities on the site. These operations and activities include site management, waste management, environmental restoration and corrective actions, and research and technology development.

  14. A major safety overhaul

    CERN Multimedia

    2003-01-01

    A redefined policy, a revamped safety course, an environmental project... the TIS (Technical Inspection and Safety) Division has begun a major safety overhaul. Its new head, Wolfgang Weingarten, explains to the Bulletin why and how this is happening.

  15. Allegheny County Major Rivers

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains locations of major rivers that flow through Allegheny County. These shapes have been taken from the Hydrology dataset. The Ohio River,...

  16. Major operations and activities

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the major operations and activities on the site. These operations and activities include site management, waste management, environmental restoration and corrective actions, and research and technology development

  17. Influence of memory theme and posttraumatic stress disorder on memory specificity in British and Iranian trauma survivors.

    Science.gov (United States)

    Jobson, Laura; Cheraghi, Sepideh

    2016-09-01

    This study investigated the influence of culture, memory theme and posttraumatic stress disorder (PTSD) on autobiographical memory specificity in Iranian and British trauma survivors. Participants completed the Autobiographical Memory Test and PTSD Diagnostic Scale. The results indicated that the British group provided significantly more personal-themed memories than the Iranian group, while the Iranian group provided significantly more social-themed memories than the British group. The British group also provided a significantly greater proportion of specific personal-themed and social-themed memories than the Iranian group. Overall, in both cultural groups memory specificity was found to be significantly correlated with PTSD symptoms. These findings provide further evidence that regardless of memory theme, specificity of autobiographical memories function to differentiate the self from others and reaffirm the independent self. They also further highlight that pan-culturally an overgeneral retrieval style may be employed by those with PTSD symptoms.

  18. Testing of environmental transfer models using data from the atmospheric release of Iodine-131 from the Hanford site, USA, in 1963. Report of the Dose Reconstruction Working Group of the Biosphere Modelling and Assessment (BIOMASS) Programme, Theme 2

    International Nuclear Information System (INIS)

    2003-03-01

    The IAEA Programme on BIOsphere Modelling and ASSessment (BIOMASS) was launched in Vienna in October 1996. The programme was concerned with developing and improving capabilities to predict the transfer of radionuclides in the environment. The programme had three themes: Theme 1: Radioactive Waste Disposal. The objective was to develop the concept of a standard or reference biosphere for application to the assessment of the long term safety of repositories for radioactive waste. Theme 2: Environmental Releases. BIOMASS provided an international forum for activities aimed at increasing the confidence in methods and models for the assessment of radiation exposure related to environmental releases. Two Working Groups addressed issues concerned with the reconstruction of radiation doses received by people from past releases of radionuclides to the environment and the evaluation of the efficacy of remedial measures. Theme 3: Biosphere Processes. The aim of this Theme was to improve capabilities for modelling the transfer of radionuclides in particular parts of the biosphere identified as being of potential radiological significance and where there were gaps in modelling approaches. This topic was explored using a range of methods including reviews of the literature, model inter-comparison exercises and, where possible, model testing against independent sources of data. Three Working Groups were established to examine the modelling of: (1) long term tritium dispersion in the environment; (2) radionuclide uptake by fruits; and (3) radionuclide migration and accumulation in forest ecosystems. This report describes results of the studies undertaken by the Dose Reconstruction Working Group under Theme 2

  19. Colonialism’s Past and Present: Performing History at a Gold Rush Theme Park

    Directory of Open Access Journals (Sweden)

    Virginia Watson

    2014-02-01

    Full Text Available The urge to seize, to claim the past in order to experience the truth of history is a powerful impulse - one full of desire for a time apart from the here and now. Conceiving and sustaining an experience of the past is today very big business. The ongoing development of the heritage, tourism and re-enactment industries inter-link with popular historical perception in ways that raise multiple questions about the relationship between popular and academic accounts of the past and the many other ways of performing history (Dening 1996. This paper takes as its starting point a gold rush theme park, Old Mogo Town in NSW Australia, and in particular, its erasure of all evidence of the Indigenous past. From here, it is my aim to develop a revised performance of that past- one that interrogates the catastrophe of colonialism and the fate of history currently expunged from the gold rush theme park of Old Mogo Town.

  20. The re-production of homosexually-themed discourse in educationally-based organised sport.

    Science.gov (United States)

    McCormack, Mark; Anderson, Eric

    2010-11-01

    In this study, we draw on findings from one year of participant observation and 12 in-depth interviews with men in a highly-ranked English university rugby team in order to nuance theoretical understandings concerning the re-production of homosexually-themed discourse in organised sport. We use ethnographic data to theorise the complex relationship between language, homosocial masculine relationships and organised sport. In examining the political, intentional and inadvertent effects of these men's discourses, we define and discuss the notion of gay discourse as a form of heteronormativity that is dissimilar to the traditional use of homophobic discourse. Highlighting that homosexually-themed discourse is best understood as a continuum, we stress the importance of context in interpreting the meaning and explicating the effects of this kind of discourse.

  1. Realistic teenage fiction with a sexrelated theme: Readers’ responses to Slinger-slinger by Francois Bloemhof

    Directory of Open Access Journals (Sweden)

    M.N. Wiggill

    2004-07-01

    Full Text Available Francois Bloemhof submitted his novel for teenagers, “Slinger-slinger” for the Sanlam competition for youth fiction in 1996. Eventually this prizewinner in the beginners’ category was published in 1997. The main theme of “Slinger-slinger” is the sexual awakening and identity of teenagers. A study was undertaken to obtain the opinions of teenage readers about the success of “Slinger-slinger” as a whole, as well as to gauge the success of integrating sexual aspects in this novel. The study also served to obtain information about the reading needs of teenage readers with regard to realistic teenage fiction and teenage fiction with a sex-related theme. The findings of the study underlying this article indicated that the participating teenage readers regarded “Slinger-slinger” as successful and interesting, and that they would like to read more realistic Afrikaans teenage fiction such as “Slinger-slinger”.

  2. Issues with data and analyses: Errors, underlying themes, and potential solutions.

    Science.gov (United States)

    Brown, Andrew W; Kaiser, Kathryn A; Allison, David B

    2018-03-13

    Some aspects of science, taken at the broadest level, are universal in empirical research. These include collecting, analyzing, and reporting data. In each of these aspects, errors can and do occur. In this work, we first discuss the importance of focusing on statistical and data errors to continually improve the practice of science. We then describe underlying themes of the types of errors and postulate contributing factors. To do so, we describe a case series of relatively severe data and statistical errors coupled with surveys of some types of errors to better characterize the magnitude, frequency, and trends. Having examined these errors, we then discuss the consequences of specific errors or classes of errors. Finally, given the extracted themes, we discuss methodological, cultural, and system-level approaches to reducing the frequency of commonly observed errors. These approaches will plausibly contribute to the self-critical, self-correcting, ever-evolving practice of science, and ultimately to furthering knowledge.

  3. Reviews of Theme 3: Human impact on erosion and sediment yield in steeplands

    Science.gov (United States)

    R. M. Rice

    1981-01-01

    In this commentary I will be discussing the acquisition and transfer of scientific information. As I perceive it, those tasks are the principal business of all of us attending this symposium. I have come to the conclusion based on my review of Theme 3 papers, that many of us are not fulfilling our obligations as scientists as adequately as we ought to when we set...

  4. Energy efficient and solar construction. Themes 2008; Energieeffizientes und solares Bauen. Themen 2008

    Energy Technology Data Exchange (ETDEWEB)

    Stadermann, Gerd (ed.)

    2009-04-15

    Within the annual meeting of the Renewable Energy Research Association (Berlin, Federal Republic of Germany) at 29th to 30th September, 2008, the lectures were held to the following themes: (a) Energy efficient and solar construction - a change of paradigm; (b) Revolution in construction technology; (c) Energetic sanitation of old buildings; (d) Innovative technologies of energy supply; (e) Integrated facility management; (f) Demonstration and practice of new technologies; (g) Market, politics, and sustainability.

  5. Theme of the Workshop on Itinerant-Electron Magnetism, and Spin Fluctuations

    Science.gov (United States)

    Yoshimura, Kazuyoshi

    2017-06-01

    The international workshop on itinerant-electron magnetism was held during September 25-27, 2015 in the seminar house of Graduate School of Science, Kyoto University, Kyoto, Japan. Here, I explain the theme of this workshop, and stress the development of itinerant-electron magnetism in several decades. The workshop was also organized in commemoration of Professor Yoshinori Takahashi’s retirement from University of Hyogo, Japan. Here, I also explain some of his works contributing to the development of itinerant magnetism.

  6. Cultural themes in elementary EFL textbooks in use in Turkey: a content analysis of pictorial representations

    OpenAIRE

    Bayrakcıl, Ferda, 1967-

    1990-01-01

    Ankara : The Faculty of Letters and the Institute of Economics and Social Sciences of Bilkent Univ., 1990. Thesis (Master's) -- Bilkent University, 1990. Includes bibliographical references leaves 75-79. The topic of this study is ”A content analysis of the cultural themes presented in pictorial form in elementary level EFL textbooks”. The literature review (see Chapter IT) concerns itself first with the general definitions of culture, as derived from anthropological, ...

  7. Utilizing Mind Mapping to Summarize English Text with the Theme "American Culture"

    OpenAIRE

    Vivi Aulia

    2017-01-01

    This research aims at knowing and describing on the utilization of mind mapping strategy in summarizing English text under the theme American Culture. It is conducted to the third semester of English Department students at STKIP PGRI Banjarmasin batch 2016 who take Reading III course. The instruments used in this research are observation sheet and documentation of students’ mind map products. The observation sheet is analyzed qualitatively by describing the important result of observation pro...

  8. Theme Park Investments: How to Beat the Average - A Case Study from the Netherlands

    OpenAIRE

    Pieter C. M. Cornelis

    2014-01-01

    (European) theme parks invest approximately 10 percent of their yearly turnover into new rides and park improvements. Without these investments these parks assume not to be a very competitive and appealing daytrip for their target audiences. However, the impact of investments in attracting new visitors is not well-known and seems to differ dramatically between parks. This paper presents a case study from the Netherlands in which a small amusement park applied a suggested, not yet proven, inve...

  9. Analyzing Primary Social Studies Curriculum of Turkey in Terms of UNESCO Educational for Sustainable Development Theme

    OpenAIRE

    Elvan YALÇINKAYA

    2013-01-01

    These three terms have been used at website of UNESCO: Sustainable development(SD), education for sustainable development (ESD) and the United Nations Decade ofEducation for Sustainable Development (DESD). In this website, it is mentioned that thethree terms have the same goal; creating abetter world for this generation and futuregenerations of all living things on planet Earth. The aim of this study is to analyzePrimary Social Studies Curriculum of Turkeyin terms of UNESCO ESD Theme. Datawas...

  10. Primary mental health prevention themes in published research and academic programs in Israel

    OpenAIRE

    Nakash, Ora; Razon, Liat; Levav, Itzhak

    2015-01-01

    Background The World Health Organization Comprehensive Mental Health Action Plan (CMHAP) 2013?2020 proposes the implementation of primary prevention strategies to reduce the mental health burden of disease. The extent to which Israeli academic programs and published research adhere to the principles spelled out by the CMHAP is unknown. Objective To investigate the presence of mental health primary prevention themes in published research and academic programs in Israel. Methods We searched for...

  11. Children's Violently Themed Play and Adult Imaginaries of Childhood: A Bakhtinian Analysis

    OpenAIRE

    Rosen, R.

    2015-01-01

    © 2015, Springer Science+Business Media Dordrecht. Children’s violently themed play has long been contentious within educational policy, parenting literature, and the academe, with conflicting views as to its immediate and long-term consequences. Yet, little attention has been given to the way in which the meanings and values attributed to childhood influence these debates. Drawing on an ethnographic study of a Nursery in London, England, this article explores the different ideas about childh...

  12. Psychologists' study on how to communicate on the theme of nuclear waste

    International Nuclear Information System (INIS)

    Guilloux, Christine

    2000-01-01

    In 1998, EDF organized a study on how to communicate on the theme of nuclear waste to help understand why communication on this theme seems to be stuck. This study has involved many psychotherapists, psychologists and physicians from different schools of thought. Afterwards a team of internal and external consultants continued the work in 1999 and explored 'the hidden aspects' of the communication that is made on nuclear waste. What are those aspects? What has to be taken into account in such a communication on a theme that is 'absorbing', 'strong', 'invisible'? How to build a more efficient and relevant communication towards the public and the ecologists? How to build a communication which opens up a dialogue and mutual understanding? The first part of this qualitative study has been devoted to interviewing the psychotherapists in a non directive way on what are the representations and beliefs about waste in general, then about nuclear waste. The second part was centered on their reactions to a pamphlet 'Nuclear waste in questions' and a video document (of a presentation of a paper given on the subject). This presentation describes the findings of this study

  13. Qualitative data analysis for health services research: developing taxonomy, themes, and theory.

    Science.gov (United States)

    Bradley, Elizabeth H; Curry, Leslie A; Devers, Kelly J

    2007-08-01

    To provide practical strategies for conducting and evaluating analyses of qualitative data applicable for health services researchers. DATA SOURCES AND DESIGN: We draw on extant qualitative methodological literature to describe practical approaches to qualitative data analysis. Approaches to data analysis vary by discipline and analytic tradition; however, we focus on qualitative data analysis that has as a goal the generation of taxonomy, themes, and theory germane to health services research. We describe an approach to qualitative data analysis that applies the principles of inductive reasoning while also employing predetermined code types to guide data analysis and interpretation. These code types (conceptual, relationship, perspective, participant characteristics, and setting codes) define a structure that is appropriate for generation of taxonomy, themes, and theory. Conceptual codes and subcodes facilitate the development of taxonomies. Relationship and perspective codes facilitate the development of themes and theory. Intersectional analyses with data coded for participant characteristics and setting codes can facilitate comparative analyses. Qualitative inquiry can improve the description and explanation of complex, real-world phenomena pertinent to health services research. Greater understanding of the processes of qualitative data analysis can be helpful for health services researchers as they use these methods themselves or collaborate with qualitative researchers from a wide range of disciplines.

  14. Suffering Daughters and Wives. Sentimental Themes in Finnish and Nordic Realism

    Directory of Open Access Journals (Sweden)

    Saija Isomaa

    2010-10-01

    Full Text Available This article examines sentimental themes and scenarios in Nordic nineteenthcentury literature, focusing on Finnish realism. The main claim of the article is that the treatment of the Woman Question in Nordic literature is thematically connected to French sentimentalism that depicted upper-class women caught in the conflict between personal freedom and familial duties. Typical scenarios were family barrier to marriage and love triangle, in which an unhappily married woman fell in love with another man. French sentimental social novels took a stance on the position of women. Similar themes and scenarios can be found in Nordic nineteenth-century novels and plays. The ‘daughter novel’ tradition from Fredrika Bremer’s The President’s Daughters (1834 to Minna Canth’s Hanna (1886 depict the sufferings of upper-class girls in patriarchal family and society. A Doll’s House (1879 by Henrik Ibsen centers on the theme of conflicting duties, depicting the moral awakening of a doll-like wife, and Papin rouva (1893, ‘The Wife of a Clergyman’ by Juhani Aho concentrates on the sufferings and moral considerations of the unhappily married Elli. The article suggests that the sentimentalist legacy informs the Nordic nineteenth-century literature and should be taken into account in the scholarship.

  15. Analysis and Comparison of Naturalistic Themes in Iranian and Britain Modern Children's Poems

    Directory of Open Access Journals (Sweden)

    Shayesteh Ebrahimi

    2016-08-01

    Full Text Available Today, children's literature given the concept of childhood, has gained a special status in the studies of humanities. Children's poetry is one of the branches of this type of literature. Naturalistic themes have the highest frequency among the themes of children poems in two countries. The population of this research consists of collections that have been published from 1921 to 2011. Children's literature was born in England in the eighteenth century and before that the first didactic books for children had come into existence in England. In addition, due to industrial growth, the emergence of the new middle class and expansion of formal education the UK was pioneering among Europe and the world countries. Therefore, to find the roots of the formation of children's literature should be referred to the UK. Therefore, in this paper Britain children’s poem has been selected to be compared with Iranian children’s poem so that by revealing the similarities and differences one can deal with the pathology of poems for children in Iran and to detect shortcomings and strengths and present some guidelines that be helpful for children and young poets as well as critics and researchers in this field. Keywords: Naturalistic themes, children literature, Iranian children's poems, Britain children's poems, comparative literature

  16. Psychologists' study on how to communicate on the theme of nuclear waste

    Energy Technology Data Exchange (ETDEWEB)

    Guilloux, Christine

    2000-07-01

    In 1998, EDF organized a study on how to communicate on the theme of nuclear waste to help understand why communication on this theme seems to be stuck. This study has involved many psychotherapists, psychologists and physicians from different schools of thought. Afterwards a team of internal and external consultants continued the work in 1999 and explored 'the hidden aspects' of the communication that is made on nuclear waste. What are those aspects? What has to be taken into account in such a communication on a theme that is 'absorbing', 'strong', 'invisible'? How to build a more efficient and relevant communication towards the public and the ecologists? How to build a communication which opens up a dialogue and mutual understanding? The first part of this qualitative study has been devoted to interviewing the psychotherapists in a non directive way on what are the representations and beliefs about waste in general, then about nuclear waste. The second part was centered on their reactions to a pamphlet 'Nuclear waste in questions' and a video document (of a presentation of a paper given on the subject). This presentation describes the findings of this study.

  17. Identifi cation of Sectarianism

    Directory of Open Access Journals (Sweden)

    Martinovich Vladimir

    2016-03-01

    Full Text Available «New religious movements and society» is traditionally one of the most sophisticated topics in the area of new religions studies. Its problem field is so huge that up to now by far not all important research themes where even touched by scientists from all over the world. The problem of the process of the identification of sectarianism by diff erent societal institutions is one of such untouched themes that is taken as the main subject of this article. This process by itself is an inseparable part of the every societal deliberate reaction to the very existence of unconventional religiosity, its unstructured and mainly structured types. The focal point of the article is step-by-step analysis of the general structure elements of the process of the identification of sectarianism without any reference to the specific time and place of its flow. Special attention is paid to the analysis of the subjects of the identification of sectarianism, to the criteria for religious groups to be qualified as new religious movements, and to the specific features of the process of documents filtration. The causes of selective perception of sectarianism are disclosed. Some main consequences and unpredictable outcomes of the process of the identification of sectarianism are described.

  18. Major international sport profiles.

    Science.gov (United States)

    Patel, Dilip R; Stier, Bernhard; Luckstead, Eugene F

    2002-08-01

    Sports are part of the sociocultural fabric of all countries. Although different sports have their origins in different countries, many sports are now played worldwide. International sporting events bring athletes of many cultures together and provide the opportunity not only for athletic competition but also for sociocultural exchange and understanding among people. This article reviews five major sports with international appeal and participation: cricket, martial arts, field hockey, soccer, and tennis. For each sport, the major aspects of physiological and biomechanical demands, injuries, and prevention strategies are reviewed.

  19. Itinerant vending of medicines inside buses in Nigeria: vending strategies, dominant themes and medicine-related information provided.

    Science.gov (United States)

    Yusuff, Kazeem B; Wassi Sanni, Abd'

    2011-07-01

    To determine vending strategies and marketing themes employed by itinerant bus vendors, and assess the accuracy and completeness of information provided on medicines being sold in an urban setting in Nigeria. Cross-sectional study and content analysis of itinerant vending of medicines inside buses recorded with a mobile telephone on purposively selected routes in a mega city with an estimated 18 million residents in southwestern Nigeria over a 2-month period. Two coders independently assessed 192 vending episodes by 56 vendors for 147 OTC and prescription medicines. Inter-rater reliability (Gwet AC1 =0.924; p<0.0001). Fourteen thousands and four hundred potential consumers encountered 192 recorded episodes of vending of medicines inside 192 buses within the study periods. Forty-four (78•5%) of the 56 vendors were females in the 30-45 years age bracket, were mostly (75%) attired in the local 'Iro and Buba' Ankara fabric and showed laminated identity cards (97.5%) issued by the local association for 'marketers' of medicines inside buses, markets, and motor parks. Of the 14400 consumers encountered inside buses during the study period, between 6.7% and 48.3% purchased the medicines promoted. Prayers against death from road traffic accidents and diseases of physical and / or meta-physical origins were the most frequently used (76•8%) ice-breaking opening statement / strategy to gain consumers' attention. Hematinics, multi-vitamins, simple analgesic, NSAIDs and corticosteroids were the most frequently vended medicines. Consumers' enquiries were related to dosing for children (51.8%), elderly (28.6%), and pregnancy (52.7%); and contra-indications during pregnancy (8.9%). Factual medicines information such as dose, frequency, potential side effects and contra-indications were not provided in majority of vending episodes. Itinerant vending of medicines and the use of misleading and melodramatic themes to secure high consumer patronage appear considerable in Nigeria

  20. Detecting themes of public concern: a text mining analysis of the Centers for Disease Control and Prevention's Ebola live Twitter chat.

    Science.gov (United States)

    Lazard, Allison J; Scheinfeld, Emily; Bernhardt, Jay M; Wilcox, Gary B; Suran, Melissa

    2015-10-01

    A diagnosis of Ebola on US soil triggered widespread panic. In response, the Centers for Disease Control and Prevention held a live Twitter chat to address public concerns. This study applied a textual analytics method to reveal insights from these tweets that can inform communication strategies. User-generated tweets were collected, sorted, and analyzed to reveal major themes. The public was concerned with symptoms and lifespan of the virus, disease transfer and contraction, safe travel, and protection of one's body. Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  1. Major New Initiatives

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Major New Initiatives. Multi-party multi-rate video conferencing OOPS. Live Lecture OOPS. Rural ATM Machine Vortex. Finger print detection HP-IITM. Medical Diagnostic kit NeuroSynaptic. LCD projection system TeNeT. Web Terminal MeTeL Midas. Entertainment ...

  2. Major planning enquiries

    Energy Technology Data Exchange (ETDEWEB)

    Shore, P

    1978-11-01

    This is a speech delivered by the U.K. Secretary of State for the Environment in Manchester (UK) on September 13th 1978. It outlines the Minister's views on the role and significance of major planning inquiries - such as that proposed to be held on the Commercial Demonstration Fast Reactor. (CDFR) (author).

  3. Major Biomass Conference

    Science.gov (United States)

    Top Scientists, Industry and Government Leaders to Gather for Major Biomass Conference America, South America and Europe will focus on building a sustainable, profitable biomass business at the Third Biomass Conference of the Americas in Montreal. Scheduled presentations will cover all biomass

  4. Therapeutic affordances of social media: emergent themes from a global online survey of people with chronic pain.

    Science.gov (United States)

    Merolli, Mark; Gray, Kathleen; Martin-Sanchez, Fernando

    2014-12-22

    Research continues to present tenuous suggestions that social media is well suited to enhance management of chronic disease and improve health outcomes. Various studies have presented qualitative reports of health outcomes from social media use and have examined discourse and communication themes occurring through different social media. However, there is an absence of published studies examining and unpacking the underlying therapeutic mechanisms driving social media's effects. This paper presents a qualitative analysis thoroughly describing what social media therapeutically affords people living with chronic pain who are self-managing their condition. From this therapeutic affordance perspective, we aim to formulate a preliminary conceptual model aimed at better understanding "how" social media can influence patient outcomes. In total, 218 people with chronic pain (PWCP) completed an online survey, investigating patient-reported outcomes (PROs) from social media use. Supplementary to quantitative data collected, participants were also given the opportunity to provide further open commentary regarding their use of social media as part of chronic pain management; 68/218 unique users (31.2%) chose to provide these free-text responses. Through thematic content analysis, 117 free-text responses regarding 10 types of social media were coded. Quotes were extracted and tabulated based on therapeutic affordances that we had previously identified. Inductive analysis was then performed to code defining language and emergent themes central to describing each affordance. Three investigators examined the responses, developed the coding scheme, and applied the coding to the data. We extracted 155 quotes from 117 free-text responses. The largest source of quotes came from social network site users (78/155, 50.3%). Analysis of component language used to describe the aforementioned affordances and emergent themes resulted in a final revision and renaming of therapeutic affordances

  5. Therapeutic Affordances of Social Media: Emergent Themes From a Global Online Survey of People With Chronic Pain

    Science.gov (United States)

    Gray, Kathleen; Martin-Sanchez, Fernando

    2014-01-01

    Background Research continues to present tenuous suggestions that social media is well suited to enhance management of chronic disease and improve health outcomes. Various studies have presented qualitative reports of health outcomes from social media use and have examined discourse and communication themes occurring through different social media. However, there is an absence of published studies examining and unpacking the underlying therapeutic mechanisms driving social media’s effects. Objective This paper presents a qualitative analysis thoroughly describing what social media therapeutically affords people living with chronic pain who are self-managing their condition. From this therapeutic affordance perspective, we aim to formulate a preliminary conceptual model aimed at better understanding "how" social media can influence patient outcomes. Methods In total, 218 people with chronic pain (PWCP) completed an online survey, investigating patient-reported outcomes (PROs) from social media use. Supplementary to quantitative data collected, participants were also given the opportunity to provide further open commentary regarding their use of social media as part of chronic pain management; 68/218 unique users (31.2%) chose to provide these free-text responses. Through thematic content analysis, 117 free-text responses regarding 10 types of social media were coded. Quotes were extracted and tabulated based on therapeutic affordances that we had previously identified. Inductive analysis was then performed to code defining language and emergent themes central to describing each affordance. Three investigators examined the responses, developed the coding scheme, and applied the coding to the data. Results We extracted 155 quotes from 117 free-text responses. The largest source of quotes came from social network site users (78/155, 50.3%). Analysis of component language used to describe the aforementioned affordances and emergent themes resulted in a final revision

  6. Epidemiology of major depressive disorder

    OpenAIRE

    Stegenga, B.T.

    2011-01-01

    Major depressive disorder (MDD) is a serious health problem and will be the second leading cause of burden of disease worldwide by 2030. To be able to prevent MDD, insight into risk factors for the onset of MDD is of clear importance. On the other hand, if onset of MDD has occurred, one may argue that different course patterns of MDD can be identified and that it is essential to examine their relationship to symptoms and function over time. Insight into these course patterns could assist in p...

  7. Lesbian, Gay, Bisexual, Transgender, and Questioning (LGBTQ)-Themed Literature for Teens: Are School Libraries Providing Adequate Collections?

    Science.gov (United States)

    Hughes-Hassell, Sandra; Overberg, Elizabeth; Harris, Shannon

    2013-01-01

    The purpose of this study was to determine if young adults have access through school libraries to LGBTQ-themed literature. The library collections in 125 high schools in one Southern U.S. state were examined for the inclusion of LGBTQ-themed fiction, nonfiction, and biographies, including a core collection of 21 recommended titles. Results showed…

  8. A semiparametric hazard model of activity timing and sequencing decisions during visits to theme parks using experimental design data

    NARCIS (Netherlands)

    Kemperman, A.D.A.M.; Borgers, A.W.J.; Timmermans, H.J.P.

    2002-01-01

    In this study we introduce a semi parametric hazard-based duration model to predict the timing and sequence of theme park visitors' activity choice behavior. The model is estimated on the basis of observations of consumer choices in various hypothetical theme parks. These parks are constructed by

  9. Global History. A Curriculum Guide. Second Semester. Theme V: The Industrial Revolution Had Global Impact. Teacher Strategies. Experimental Edition.

    Science.gov (United States)

    New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.

    Designed to assist teachers and supervisors in the implementation of the global history course, this bulletin presents learning activities which include the rationale, performance objectives, and teaching strategies related to Theme V entitled, "The Industrial Revolution Had Global Impact." This theme has seven subthemes: (1)…

  10. Reflections on the Journal of Applied Psychology for 1989 to 1994: Changes in major research themes and practices over 25 years.

    Science.gov (United States)

    Schmitt, Neal

    2017-03-01

    Informal observations concerning journal content indicates that research investigating organizational behavior topics, including work on the structure of groups and determinants and consequences of group process along with the role of leadership in groups, has increased. Some topics have disappeared (e.g., job analysis, human factors, union-related work, consumer behavior) and others are declining (e.g., research methods, psychometrics). Perhaps the biggest change is in the length of articles, which is mostly a function of the inclusion of greater numbers of references and appendix material. Publishing some of this material in supplementary online materials is now current practice in the Journal of Applied Psychology. Concerns about use of journal space may also be entirely moot, if electronic publishing as opposed to print publishing becomes the norm. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Symbols of menarche identified by African American females.

    Science.gov (United States)

    Hawthorne, Dorothy J

    2002-08-01

    This study was conducted to identify and describe symbolic themes of menarche. The qualitative case study design was used with a purposive sample of 30 participants (15 mothers and their 15 daughters) in answering 2 questions: (a) How do 9- and 10-year-old African American girls view the meaning of their menarcheal flow?, and (b) How do African American mothers view the meaning of menarche? Data were collected through interviews 2 to 5 days after completion of menarche. A cross-case comparison analysis of the interviews revealed 4 themes: (a) vaginal bleeding, (b) sexual maturation, (c) premenarcheal sexual activity, and (d) sexual payback to fathers. With the exception of the latter all themes were supported in earlier studies of Euro-American girls. These findings indicate the need for further research addressing self-concept at menarche, impact of menarche on family relationships, and views of fathers about sexual payback as a symbol of menarche.

  12. Spiritual and religious components of patient care in the neonatal intensive care unit: sacred themes in a secular setting.

    Science.gov (United States)

    Catlin, E A; Guillemin, J H; Thiel, M M; Hammond, S; Wang, M L; O'Donnell, J

    2001-01-01

    We hypothesized that spiritual distress was a common, unrecognized theme for neonatal intensive care unit (NICU) care providers. An anonymous questionnaire form assigned to a data table in a relational database was designed. Surveys were completed by 66% of NICU staff. All respondents viewed a family's spiritual and religious concerns as having a place in patient care. Eighty-three percent reported praying for babies privately. Asked what theological sense they made of suffering of NICU babies, 2% replied that children do not suffer in the NICU. Regarding psychological suffering of families, the majority felt God could prevent this, with parents differing (p = 0.039) from nonparents. There exists a strong undercurrent of spirituality and religiosity in the study NICU. These data document actual religious and spiritual attitudes and practices and support a need for pastoral resources for both families and care providers. NICU care providers approach difficulties of their work potentially within a religious and spiritual rather than a uniquely secular framework.

  13. Interprofessional collaboration and family member involvement in intensive care units: emerging themes from a multi-sited ethnography.

    Science.gov (United States)

    Reeves, Scott; McMillan, Sarah E; Kachan, Natasha; Paradis, Elise; Leslie, Myles; Kitto, Simon

    2015-05-01

    This article presents emerging findings from the first year of a two-year study, which employed ethnographic methods to explore the culture of interprofessional collaboration (IPC) and family member involvement in eight North American intensive care units (ICUs). The study utilized a comparative ethnographic approach - gathering observation, interview and documentary data relating to the behaviors and attitudes of healthcare providers and family members across several sites. In total, 504 hours of ICU-based observational data were gathered over a 12-month period in four ICUs based in two US cities. In addition, 56 semi-structured interviews were undertaken with a range of ICU staff (e.g. nurses, doctors and pharmacists) and family members. Documentary data (e.g. clinical guidelines and unit policies) were also collected to help develop an insight into how the different sites engaged organizationally with IPC and family member involvement. Directed content analysis enabled the identification and categorization of major themes within the data. An interprofessional conceptual framework was utilized to help frame the coding for the analysis. The preliminary findings presented in this paper illuminate a number of issues related to the nature of IPC and family member involvement within an ICU context. These findings are discussed in relation to the wider interprofessional and health services literature.

  14. Variations in dream recall frequency and dream theme diversity by age and sex

    Directory of Open Access Journals (Sweden)

    Tore eNielsen

    2012-07-01

    Full Text Available We assessed dream recall frequency and dream theme diversity with an internet questionnaire among a cohort of 28,888 male and female participants aged 10 to 79 years in a cross-sectional design. Dream recall frequency increased from adolescence (ages 10-19 to early adulthood (20-29 and then decreased again for the next 20 years. The nature of this decrease differed for males and females. For males, it began earlier (30-39, proceeded more gradually, and reached a nadir earlier (40-49 than it did for females. For females, it began later (40-49, dropped more abruptly, and reached nadir later (50-59. Marked sex differences were observed for age strata 10-19 through 40-49 and year-by-year analyses estimated the window for these differences to be more precisely from 14-44 yrs. Dream theme diversity decreased linearly with age for both sexes up to 50-59 and then dropped even more sharply for 60-79. There was a sex difference favouring males on this measure but only for ages 10-19. Findings replicate, in a single sample, those from several previous studies showing an increase in dream recall frequency from adolescence to early adulthood, a subsequent decrease in dream recall frequency—primarily in early and middle adulthood, and different patterns of age-related decrease in the two sexes. Age-related changes in sleep structure, such as decreasing %REM sleep, parallel the observed dream recall changes but are much smaller and more gradual in nature. Changes in the phase and amplitude of circadian rhythms of REM propensity and generational differences in life experiences may also account for some part of the findings. However, that decreases in dream theme diversity parallel known age-related decreases in episodic and autobiographical memory may signify that the diversity measure indexes an aspect of autobiographical memory that is specific to dream recall.

  15. Recruitment Strategies for Geoscience Majors: Conceptual Framework and Practical Suggestions

    Science.gov (United States)

    Richardson, R. M.; Eyles, C.; Ormand, C. J.

    2009-12-01

    One characteristic of strong geoscience departments is that they recruit and retain quality students. In a survey to over 900 geoscience departments in the US and Canada several years ago nearly 90% of respondents indicated that recruiting and retaining students was important. Two years ago we offered a pre-GSA workshop on recruiting and retaining students that attracted over 30 participants from over 20 different institutions, from liberal arts colleges to state universities to research intensive universities. Since then we have sought additional feedback from a presentation to the AGU Heads & Chairs at a Fall AGU meeting, and most recently from a workshop on strengthening geoscience programs in June 2009. In all of these settings, a number of themes and concrete strategies have emerged. Key themes included strategies internal to the department/institution; strategies that reach beyond the department/institution; determining how scalable/transferable strategies that work in one setting are to your own setting; identifying measures of success; and developing or improving on an existing action plan specific to your departmental/institutional setting. The full results of all of these efforts to distill best practices in recruiting students will be shared at the Fall AGU meeting, but some of the best practices for strategies local to the department/institution include: 1) focusing on introductory classes (having the faculty who are most successful in that setting teach them, having one faculty member make a common presentation to all classes about what one can do with a geoscience major, offering topical seminars, etc.); 2) informing students of career opportunities (inviting alumni back to talk to students, using AGI resources, etc.,); 3) creating common space for students to work, study, and be a community; 4) inviting all students earning an ‘A’ (or ‘B’) in introductory classes to a departmental event just for them; and 5) creating a field trip for incoming

  16. Examining emergency department communication through a staff-based participatory research method: identifying barriers and solutions to meaningful change.

    Science.gov (United States)

    Cameron, Kenzie A; Engel, Kirsten G; McCarthy, Danielle M; Buckley, Barbara A; Mercer Kollar, Laura Min; Donlan, Sarah M; Pang, Peter S; Makoul, Gregory; Tanabe, Paula; Gisondi, Michael A; Adams, James G

    2010-12-01

    We test an initiative with the staff-based participatory research (SBPR) method to elicit communication barriers and engage staff in identifying strategies to improve communication within our emergency department (ED). ED staff at an urban hospital with 85,000 ED visits per year participated in a 3.5-hour multidisciplinary workshop. The workshop was offered 6 times and involved: (1) large group discussion to review the importance of communication within the ED and discuss findings from a recent survey of patient perceptions of ED-team communication; (2) small group discussions eliciting staff perceptions of communication barriers and best practices/strategies to address these challenges; and (3) large group discussions sharing and refining emergent themes and suggested strategies. Three coders analyzed summaries from group discussions by using latent content and constant comparative analysis to identify focal themes. A total of 127 staff members, including attending physicians, residents, nurses, ED assistants, and secretaries, participated in the workshop (overall participation rate 59.6%; range 46.7% to 73.3% by staff type). Coders identified a framework of 4 themes describing barriers and proposed interventions: (1) greeting and initial interaction, (2) setting realistic expectations, (3) team communication and respect, and (4) information provision and delivery. The majority of participants (81.4%) reported that their participation would cause them to make changes in their clinical practice. Involving staff in discussing barriers and facilitators to communication within the ED can result in a meaningful process of empowerment, as well as the identification of feasible strategies and solutions at both the individual and system levels. Copyright © 2010 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

  17. Spatial data on energy, environmental, and socioeconomic themes at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R. J.; Watts, J. A.; Shonka, D. B.; Leobe, A. S.; Johnson, M. L.; Ogle, M. C.; Malthouse, N. S.; Madewell, D. G.; Hull, J. F.

    1977-02-01

    Spatial data files covering energy, environmental, and socioeconomic themes at Oak Ridge National Laboratory (ORNL) are described. The textual descriptions are maintained by the Regional and Urban Studies Information Center (RUSTIC) within the Data Management and Analysis Group, Energy Division, as part of the Oak Ridge Computerized Hierarchical Information System (ORCHIS) and are available for online retrieval using the ORLOOK program. Descriptions provide abstracts, geographic coverage, original data source, availability limitations, and contact person. Most of the files described in this document are available on a cost-recovery basis.

  18. Themes, scenes, and taste in the history of Japanese garden art

    OpenAIRE

    Kuitert, W.

    1988-01-01

    The present study deals - in its three parts - with three fragments of the garden history of Japan. It reveals how the meaning a garden had to the people of its time was significantly different in all of these periods.

    Part one, titled "Themes", deals with the later Heian period, from the tenth until the late twelfth century. The foundations of a native, Japanese tradition of garden art were laid. The first chapters introduce the palace gardens of the courtly aristocracy in t...

  19. Short Notes on the Prosopography of the Byzantine Theme of Koloneia (Part I

    Directory of Open Access Journals (Sweden)

    Pantelis CHARALAMPAKIS

    2016-12-01

    Full Text Available This study, the first part of two, presents short notes and comments on the officials of the Byzantine theme of Koloneia. Two Byzantine lead seals are published here for the first time. One belongs to Leon, krites of Koloneia, the other to Michael, anagrapheus and krites of Koloneia and Sebasteia. The lost inscription of Ioannes, droungarios of Koloneia is also presented here, together with a previously unnoticed reference to another droungarios in the Passio of the 42 Martyrs of Amorion. The lists of the kritai and strategoi of Koloneia are completed on the basis of recently discovered and published, but also unpublished evidence.

  20. Panel Discussion: Common Themes Across ``Bringing Newcomers Into The Physics Community''

    Science.gov (United States)

    Little, Angela

    2014-03-01

    I will be facilitating a discussion between the audience and the four speakers in this session: Dimitri Dounas-Frazer, Catherine Good, Casey Miller, and Katie Hinko. They will all be speaking on the same general topic of supporting newcomers to the physics community at critical transition points but come from a set of diverse contexts and perspectives. Their work spans a wide age range of STEM students and they approach their work through many different lenses: as physics faculty, program directors, education and psychology researchers, and combinations thereof. Broad themes across these contexts and perspectives will be explored such as the role of growth mindset, community, and professional development.

  1. Necessary text genres and themes to act in professional and academic contexts in Biotechonology

    Directory of Open Access Journals (Sweden)

    Sara Fernandes Lima

    2012-10-01

    Full Text Available Considering the existing gap in the Brazilian context of researches in the area of specific purpose course planning based on text genres (RAMOS, 2004 and trying to contribute to its development, we present the text genres and themes evaluated as necessary to act in professional and academic contexts of the Biotechnology area. To map these necessities, we applied a questionnaire to students and teachers, in a federal institution, and analyzed the results based on the sociodiscoursive interactionism principles, theory which has Bronckart, Schneuwly and Dolz (MACHADO, 2005 as precursors.

  2. [Discipline construction is the theme of the development of burn surgery].

    Science.gov (United States)

    Jia, C Y

    2018-03-20

    Discipline construction is the core element of department development, including discipline structure setting, scale, equipment, medical workers structure, clinical feature and advantage, talent training, teaching level, scientific research level, management system, and cultural construction of department. As leader and engine of discipline construction, directors' ability is an important factor for discipline construction. Clinical characteristic is the basis of discipline construction; innovation actuation is the essence of discipline construction; talents training is the guarantee of discipline construction; scientific research is the wing of discipline construction; cultural construction is the hot spring of discipline construction. Discipline construction is the theme of the development of burn surgery.

  3. Extracellular vesicles, tissue factor, cancer and thrombosis – discussion themes of the ISEV 2014 Educational Day

    Directory of Open Access Journals (Sweden)

    Chris Gardiner

    2015-03-01

    Full Text Available Although the association between cancer and venous thromboembolism (VTE has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV and International Society on Thrombosis and Haemostasis (ISTH held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.

  4. The Electro-Federation holds its annual conference under the theme of convergence

    International Nuclear Information System (INIS)

    Anon.

    1998-01-01

    An outline of the program for the 1998 annual meeting of the Canadian Electro-Federation was presented. The meeting was held in Quebec City in June 1998 under the theme C onverging competencies: The channel of choice . The meeting was designed to provide relevant information to the participants on the topics of deregulation. The federation invited the participation of delegates from the Canadian Association of Electrical Manufacturers. One of the highlights of the conference was a panel discussion by industry experts on the topic of converging competencies. The conference also included the usual private meetings between manufacturers and distributors of electrical equipment

  5. Exploring patient experiences with prescription medicines to identify unmet patient needs: implications for research and practice.

    Science.gov (United States)

    Kucukarslan, Suzan N; Lewis, Nancy J W; Shimp, Leslie A; Gaither, Caroline A; Lane, Daniel C; Baumer, Andrea L

    2012-01-01

    Pharmacy services are offered to patients, and often, they decline participation. Research is needed to better understand patients' unmet needs when taking prescribed medications. To identify and characterize patients' unmet needs related to using prescribed medication for chronic conditions. Focus groups of patients using prescription medication for chronic conditions discussed their experiences with medications, starting from initial diagnosis to ongoing management. Sessions involved 40 patients from 1 Midwestern U.S. state. Major themes were identified using content analysis. Three major themes emerged. First, patients seek information to understand their health condition and treatment rationale. Patients form an illness perception (its consequence, controllability, cause, and duration) that dictates their actions. Second, patients desire to be involved in treatment decisions, and they often feel that decisions are made for them without their understanding of the risk-to-benefit trade-off. Third, patients monitor the impact of treatment decisions to determine if anticipated outcomes are achieved. The results were consistent with Dowell's therapeutic alliance model (TAM) and Leventhal's common sense model (CSM). The TAM can be used to model the consultative services between pharmacists and patients. The impact of the new services (or interventions) can be evaluated using the CSM. Patients expressed a strong desire to be involved in their treatment decisions. The effectiveness of medication therapy management services may be enhanced if pharmacists build on patients' desire to be involved in their treatment decisions and assist them to understand the role of medications and their risks and expected outcomes within the context of the patients' perceptions of illness and desired coping strategies. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Characterization of a novel theme C glycoside hydrolase family 9 cellulase and its CBM-chimeric enzymes.

    Science.gov (United States)

    Duan, Cheng-Jie; Huang, Ming-Yue; Pang, Hao; Zhao, Jing; Wu, Chao-Xing; Feng, Jia-Xun

    2017-07-01

    In bacterial cellulase systems, glycoside hydrolase family 9 (GH9) cellulases are generally regarded as the major cellulose-degrading factors besides GH48 exoglucanase. In this study, umcel9A, which was cloned from uncultured microorganisms from compost, with the encoded protein being theme C GH9 cellulase, was heterologously expressed in Escherichia coli, and the biochemical properties of the purified enzyme were characterized. Hydrolysis of carboxylmethylcellulose (CMC) by Umcel9A led to the decreased viscosity of CMC solution and production of reducing sugars. Interestingly, cellobiose was the major product when cellulosic materials were hydrolyzed by Umcel9A. Six representative carbohydrate-binding modules (CBMs) from different CBM families (CBM1, CBM2, CBM3, CBM4, CBM10, and CBM72) were fused with Umcel9A at the natural terminal position, resulting in significant enhancement of the binding capacity of the chimeric enzymes toward four different insoluble celluloses as compared with that of Umcel9A. Catalytic activity of the chimeric enzymes against insoluble celluloses, including phosphoric acid-swollen cellulose (PASC), alkali-pretreated sugarcane bagasse (ASB), filter paper powder (FPP), and Avicel, was higher than that of Umcel9A, except for Umcel9A-CBM3. In these chimeric enzymes, CBM4-Umcel9A exhibited the highest activity toward the four tested insoluble celluloses and displayed 4.2-, 3.0-, 2.4-, and 6.6-fold enhanced activity toward PASC, ASB, FPP, and Avicel, respectively, when compared with that of Umcel9A. CBM4-Umcel9A also showed highest V max and catalytic efficiency (k cat /K M ) against PASC. Construction of chimeric enzymes may have potential applications in biocatalytic processes and provides insight into the evolution of the molecular architecture of catalytic module and CBM in GH9 cellulases.

  7. The Ursa Major supercluster

    International Nuclear Information System (INIS)

    Schuch, N.J.

    1983-01-01

    An optical and a radio survey have been carried out. The optical observations consist of a spectroscopic survey in which redshift data for cluster galaxies and optical identifications of radio sources were obtained with the 98-inch Isaac Newton telescope at the Royal Greenwich Observatory, and the 200-inch Hale telescope; the photographic survey in B, V and R colors was made with the 48-inch Schmidt telescope at Palomar. Some results on the galaxy distribution in the Ursa Major supercluster are briefly discussed. (Auth.)

  8. Securing Major Events

    International Nuclear Information System (INIS)

    Loeoef, Susanna

    2013-01-01

    When asked why the IAEA should provide nuclear security support to countries that organize large public events, Nuclear Security Officer Sophia Miaw answers quickly and without hesitation. ''Imagine any major public event such as the Olympics, a football championship, or an Expo. If a dirty bomb were to be exploded at a site where tens of thousands of people congregate, the radioactive contamination would worsen the effects of the bomb, increase the number of casualties, impede a rapid emergency response, and cause long term disruption in the vicinity,'' she said. Avoiding such nightmarish scenarios is the driving purpose behind the assistance the IAEA offers States that host major sporting or other public events. The support can range from a single training course to a comprehensive programme that includes threat assessment, training, loaned equipment and exercises. The type and scope of assistance depends on the host country's needs. ''We incorporate nuclear security measures into their security plan. We don't create anything new,'' Miaw said

  9. Common themes and cell type specific variations of higher order chromatin arrangements in the mouse

    Directory of Open Access Journals (Sweden)

    Cremer Thomas

    2005-12-01

    Full Text Available Abstract Background Similarities as well as differences in higher order chromatin arrangements of human cell types were previously reported. For an evolutionary comparison, we now studied the arrangements of chromosome territories and centromere regions in six mouse cell types (lymphocytes, embryonic stem cells, macrophages, fibroblasts, myoblasts and myotubes with fluorescence in situ hybridization and confocal laser scanning microscopy. Both species evolved pronounced differences in karyotypes after their last common ancestors lived about 87 million years ago and thus seem particularly suited to elucidate common and cell type specific themes of higher order chromatin arrangements in mammals. Results All mouse cell types showed non-random correlations of radial chromosome territory positions with gene density as well as with chromosome size. The distribution of chromosome territories and pericentromeric heterochromatin changed during differentiation, leading to distinct cell type specific distribution patterns. We exclude a strict dependence of these differences on nuclear shape. Positional differences in mouse cell nuclei were less pronounced compared to human cell nuclei in agreement with smaller differences in chromosome size and gene density. Notably, the position of chromosome territories relative to each other was very variable. Conclusion Chromosome territory arrangements according to chromosome size and gene density provide common, evolutionary conserved themes in both, human and mouse cell types. Our findings are incompatible with a previously reported model of parental genome separation.

  10. Providing Geospatial Education and Real World Applications of Data across the Climate Initiative Themes

    Science.gov (United States)

    Weigel, A. M.; Griffin, R.; Bugbee, K.

    2015-12-01

    Various organizations such as the Group on Earth Observations (GEO) have developed a structure for general thematic areas in Earth science research, however the Climate Data Initiative (CDI) is addressing the challenging goal of organizing such datasets around core themes specifically related to climate change impacts. These thematic areas, which currently include coastal flooding, food resilience, ecosystem vulnerability, water, transportation, energy infrastructure, and human health, form the core of a new college course at the University of Alabama in Huntsville developed around real-world applications in the Earth sciences. The goal of this course is to educate students on the data available and scope of GIS applications in Earth science across the CDI climate themes. Real world applications and datasets serve as a pedagogical tool that provide a useful medium for instruction in scientific geospatial analysis and GIS software. With a wide range of potential research areas that fall under the rubric of "Earth science", thematic foci can help to structure a student's understanding of the potential uses of GIS across sub-disciplines, while communicating core data processing concepts. The learning modules and use-case scenarios for this course demonstrate the potential applications of CDI data to undergraduate and graduate Earth science students.

  11. Discontinuous Residue and Theme in Higher-Order Semiotic: A Case for Interlocking Systems

    Directory of Open Access Journals (Sweden)

    Ali Akbar Farahani

    2008-11-01

    Full Text Available The fallacy persists in discourse analysis research to explore lexicogrammatical phenomena detached from any adjacent plane of the meaning potential. In an attempt to dispel this and toss out some preconceived notions about what a modern SFG vantage point should involve, this study homes in on one aspect of SFG within prose fiction in particular, which is very revealing in terms of how separate system networks are actually in synergistic simultaneity, and how SFG allows one , phenomenally well, to bring such synergies out, getting to the heart of the fact that language pervasively operates on multiple planes of textuality simultaneously. Thus, building upon Halliday’s 2004 work, the quest is if it is interpersonally significant when the Residue is split into two parts; more importantly, if it is also laced with some lexicogrammatical quality on the textual plane, in light of the fairly well-entrenched assumption that there is always Theme at work when the Residue is split. Halliday is the only scholar to touch upon the topic of Discontinuous Residue and its relationship to Marked Theme in the culmination of his groundbreaking career, i.e. his 2004 work. Having driven home the proposal to make into a watchword the ubiquity of interlocking macro-semantic system networks, some pedagogical and research implications and suggestions flowing from this are brought up.

  12. Pedagogical workshops as a teaching and learning strategy: the hydrographic basic as a theme

    Directory of Open Access Journals (Sweden)

    Valéria Brumato Regina Fornazari

    2017-08-01

    Full Text Available Current research investigates the ideas and practices of a team of teachers of the Natural Sciences working in schools in the state of Paraná, Brazil, with regard to pedagogical workshops as teaching and learning strategies on Hydrographic Basin as theme. A continuous formation course was conducted on the theme, with data retrieved by a questionnaire applied prior to the course and after the development of workshops by the teachers. Films, recordings and descriptive memorials were analyzed according to content analysis. Results showed that teachers endeavored to problematize in the pedagogical workshops, coupled to teachers´ mediation to go beyond common sense. Students´ participation was the great progress mediated by workshops. On the other hand, interdisciplinarity and the problematization of teaching were the limiting presuppositions for their execution. The undertaking enhanced a better understanding of pedagogical workshops in the teaching of the sciences, with the need for greater investments in teachers´ continuous formation to enhance the development of teaching practices that attend to current demands in science teaching.

  13. The use of biblical themes in the debate concerning the xenophobic attacks in South Africa

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    Zorodzai Dube

    2015-03-01

    Full Text Available The study draws from the ideas of J�rgen Habermas, Daniel Trotter and Christian Fuchs, Zizi Papacharissis, Yochai Benkler and Christian Fuchs to investigate the use of social media as a platform to express ideas against xenophobic-related attacks in South Africa (April 2015�May 2015. The data was collected from twitter, YouTube and Facebook. Most views came from the Facebook platform called �Stop xenophobia�. Using ATLAS.ti, software for qualitative research, the data was coded into interpretive variables or categories. The results show that themes such as hospitality, morality, creation and ethics received highest frequency as reasons to condemn xenophobia. The research further reveals that the social media data is much candid in comparison to state controlled media, where views and ideas were censored to protect the economic and public image of the country. Unlike the controlled government outlets which focus on the possible correlation between xenophobic attacks to economic outlook, the social media focuses on moral and ethical issues � issues that define our collective as human beings and tackles xenophobia from the perspective of ethics and shared human values.Intradisciplinary and/or interdisciplinary implications: This study is interdisciplinary in nature due to the use of theories in media studies and social sciences to investigate the use of biblical themes in the fight against xenophobia.

  14. Ethical concerns as a methodological proposal to approach cross-cutting themes.

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    Sansao Albino Timbane

    2015-12-01

    Full Text Available The present study highlight how the investment in ethical concerns can contribute as a learning shuttle in a virtual ambient directed to the learning, more than to the teaching. Face-to-face meetings, in a classroom, and distance meetings, on Forchat online space were made. The students proactively participated on the discussions with freedom to decide about the paper’s assumption and thematic propositions according to the personal interest on the studies topics, sometimes as a moderator, other times as contributor, without the teacher interference.  The reality problematization through the ethical concerns presented as relevant effect the proactively engagement on the discussions about the proposed topics, with gains to the conceptual construction and to the methodological positions in the research.  Instigated by the challenge of cross-cutting themes discussed, on a virtual learning ambient, themes related with: docent practice, learning, professional formation, evaluation, theory- practice relation, refreshing debates and reflections about ethical concerns, making a collective text which at same time respected the individual contributions heterogeneity and the produced senses.

  15. Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

    Science.gov (United States)

    Barwell, James; Gingell, Joseph J; Watkins, Harriet A; Archbold, Julia K; Poyner, David R; Hay, Debbie L

    2012-05-01

    The calcitonin receptor (CTR) and calcitonin receptor-like receptor (CLR) are two of the 15 human family B (or Secretin-like) GPCRs. CTR and CLR are of considerable biological interest as their pharmacology is moulded by interactions with receptor activity-modifying proteins. They also have therapeutic relevance for many conditions, such as osteoporosis, diabetes, obesity, lymphatic insufficiency, migraine and cardiovascular disease. In light of recent advances in understanding ligand docking and receptor activation in both the family as a whole and in CLR and CTR specifically, this review reflects how applicable general family B GPCR themes are to these two idiosyncratic receptors. We review the main functional domains of the receptors; the N-terminal extracellular domain, the juxtamembrane domain and ligand interface, the transmembrane domain and the intracellular C-terminal domain. Structural and functional findings from the CLR and CTR along with other family B GPCRs are critically appraised to gain insight into how these domains may function. The ability for CTR and CLR to interact with receptor activity-modifying proteins adds another level of sophistication to these receptor systems but means careful consideration is needed when trying to apply generic GPCR principles. This review encapsulates current thinking in the realm of family B GPCR research by highlighting both conflicting and recurring themes and how such findings relate to two unusual but important receptors, CTR and CLR. © 2011 The Authors. British Journal of Pharmacology © 2011 The British Pharmacological Society.

  16. Trends in the investigation of social determinants of health: selected themes and methods

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    Roger Keller Celeste

    2011-01-01

    Full Text Available We analyze bibliometric trends of topics relevant to the epidemiologic research of social determinants of health. A search of the PubMed database, covering the period 1985-2007, was performed for the topics: socioeconomic factors, sex, race/ethnicity, discrimination/prejudice, social capital/support, lifecourse, income inequality, stress, behavioral research, contextual effects, residential segregation, multilevel modeling, regression based indices to measure inequalities, and structural equation modeling/causal diagrams/path analysis. The absolute, but not the relative, frequency of publications increased for all themes. Total publications in PubMed increased 2.3 times, while the subsets of epidemiology/public health and social epidemiologic themes/methods increased by factors of 5.3 and 5.2, respectively. Only multilevel and contextual analyses had a growth over and above that observed for epidemiology/public health. We conclude that there is clearly room for wider use of established techniques, and for new methods to emerge when they satisfy theoretical needs.

  17. A hydrogen economy: an answer to future energy problems. [Overview of 1974 THEME Conference

    Energy Technology Data Exchange (ETDEWEB)

    Seifritz, W [Eidgenoessisches Inst. fuer Reaktorforschung, Wuerenlingen (Switzerland)

    1975-06-01

    ''The Theme was THEME''. This was the headline of The Hydrogen Economy Miami Energy Conference which was the first international conference of this type and which took place in Miami, March 18-20, 1974. For the first time, about 700 participants from all over the western world discussed all the ramifications and aspects of a hydrogen based economy. Non-fossil hydrogen, produced from water by either electrolysis or by direct use of process heat from a nuclear source is a clean, all-synthetic, automatically recyclable, and inexhaustible fuel. It may support the World's future energy requirements beyond the present self limited fossil-fuel era. A large number of papers and news were presented on this conference reflecting this effort. The following article is intended to report on the highlights of the conference and to give a survey on the present state of the art in the hydrogen field. Furthermore, the author includes his own ideas and conclusions predominantly by taking into account the trends in the development of future nuclear reactor systems and symbiotic high-temperature-reactor/breeder strategies being the primary energy input of a hydrogen economy and providing a most promising avenue for solving both the World's energy and environmental (entropy) problems.

  18. Representations of Self and Parents, and Relationship Themes, in Adolescents with Post Traumatic Stress Disorder (PTSD).

    Science.gov (United States)

    Shafran, Naama; Shahar, Golan; Berant, Ety; Gilboa-Schechtman, Eva

    2016-07-01

    Negative perceptions of self and others have lately become one of the criteria for Posttraumatic Stress Disorder (PTSD) among adults and adolescents. Drawing from theories of mental representations in psychopathology, this study examined self-reported negative cognitions, self and parental representations, and relationship themes among adolescents with and without PTSD. Thirty one adolescents with PTSD (11 boys, mean age = 14.06, SD = 2.24) were matched with 29 adolescents who had no psychiatric diagnosis (11 boys, mean age = 14.96, SD = 1.78). Adolescents completed self-report measures, wrote a description of self, mother and father, and were interviewed about positive and negative relationship episodes with mother, father, and peers. Adolescents with PTSD reported more self-criticism and performance evaluation than did controls. Their self-representation exhibited a lower sense of agency, which was related to structural variables (i.e., less integrative description). Although parental representations of adolescents with PTSD were not generally less benevolent or more punitive than those of controls, their relationship themes revealed a higher proportion of the wish to be distant from others. Adolescents with PTSD exhibited more passive responses and perceived more dominant or controlling responses from their parents. Findings point out to a serious impairment in representations of self and relationship patterns in adolescent PTSD.

  19. "Old Oxen Cannot Plow": Stereotype Themes of Older Adults in Turkish Folklore.

    Science.gov (United States)

    Marcus, Justin; Sabuncu, Neslihan

    2016-12-01

    Although much research has established the nature of attitudes and stereotypes toward older adults, there are conflicting explanations for the root cause of ageism, including the sociocultural view and interpersonal views, that age bias against older adults is uniquely a product of modernity and occurs through social interactions, and the evolutionary view and intraindividual views, that age bias against older adults is rooted in our naturally occurring and individually held fear of death. We make initial investigations into resolving this conflict, by analyzing literature from a society predating the Industrial Revolution, the society of Ottoman Turks. Using Grounded Theory, we analyzed 1,555 Turkish fairy tales of the most well-known older adult in Turkish folklore, Nasreddin Hoca, for stereotype themes of older adults. Using the same method, we then analyzed 22,000+ Turkish sayings and proverbs for the same themes. Results indicated older adults to be viewed both positively and negatively. Positive stereotypes included wisdom, warmth, deserving of respect, and retirement. Negative stereotypes included incompetence, inadaptability, and frailty/nearing of death. Older females were viewed more negatively relative to older males. Results indicated views of older adults to parallel those found in contemporary research. Results have implications for the design of interventions to reduce ageism and on the cross-cultural generalizability of age-based stereotypes. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. PRESENTATION OF VIOLENCE IN L OVE THEMED TV SERIES IN TURKE Y

    Directory of Open Access Journals (Sweden)

    Çiğdem TAŞ ALİCENAP

    2013-06-01

    Full Text Available Violence is an inseparable part of our lives. Mass media is the public domain in which the violence is widely presented. Among all the mass media mediums which have numerous functions in our daily lives such as informing, entertaining, educating, etc.; television, without a doubt, takes the highest amount of time. In recent years, the number of television series on channels has increased and the fact of violence has been presented in these programs. Here in this research it has been questioned whether physical, psychological and verbal violence are used in love-themed TV series or not; and if yes, it has been questioned who is inflicting violence towards whom. In this context four love-themed TV series which were broadcasted in four Turkish channels with the highest rating record between the years of 2006 and 2010 were studied by using content analysis method in accordance with the violence categories. The data gathered by the analysis has shown that not only the series based on action; but also the series based on human affairs such as family, friendship, love, etc. include violence.

  1. Core Themes in Music Therapy Clinical Improvisation: An Arts-Informed Qualitative Research Synthesis.

    Science.gov (United States)

    Meadows, Anthony; Wimpenny, Katherine

    2017-07-01

    Although clinical improvisation continues to be an important focus of music therapy research and practice, less attention has been given to integrating qualitative research in this area. As a result, this knowledge base tends to be contained within specific areas of practice rather than integrated across practices and approaches. This qualitative research synthesis profiles, integrates, and re-presents qualitative research focused on the ways music therapists and clients engage in, and make meaning from, clinical improvisation. Further, as a conduit for broadening dialogues, opening up this landscape fully, and sharing our response to the analysis and interpretation process, we present an arts-informed re-presentation of this synthesis. Following an eight-step methodological sequence, 13 qualitative studies were synthesized. This included reciprocal and refutational processes associated with synthesizing the primary studies, and additional steps associated with an arts-informed representation. Three themes, professional artistry, performing self, and meaning-making, are presented. Each theme is explored and exemplified through the selected articles, and discussed within a larger theoretical framework. An artistic re-presentation of the data is also presented. Music therapists use complex frameworks through which to engage clients in, and make meaning from, improvisational experiences. Artistic representation of the findings offers an added dimension to the synthesis process, challenging our understanding of representation, and thereby advancing synthesis methodology. © the American Music Therapy Association 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  2. The Most Common Feedback Themes in Communication Skills Training in an Internal Medicine Residency Program: Lessons from the Resident Audio-Recording Project.

    Science.gov (United States)

    Han, Heeyoung; Papireddy, Muralidhar Reddy; Hingle, Susan T; Ferguson, Jacqueline Anne; Koschmann, Timothy; Sandstrom, Steve

    2018-07-01

    Individualized structured feedback is an integral part of a resident's learning in communication skills. However, it is not clear what feedback residents receive for their communication skills development in real patient care. We will identify the most common feedback topics given to residents regarding communication skills during Internal Medicine residency training. We analyzed Resident Audio-recording Project feedback data from 2008 to 2013 by using a content analysis approach. Using open coding and an iterative categorization process, we identified 15 emerging themes for both positive and negative feedback. The most recurrent feedback topics were Patient education, Thoroughness, Organization, Questioning strategy, and Management. The residents were guided to improve their communication skills regarding Patient education, Thoroughness, Management, and Holistic exploration of patient's problem. Thoroughness and Communication intelligibility were newly identified themes that were rarely discussed in existing frameworks. Assessment rubrics serve as a lens through which we assess the adequacy of the residents' communication skills. Rather than sticking to a specific rubric, we chose to let the rubric evolve through our experience.

  3. Culture and alcohol use: historical and sociocultural themes from 75 years of alcohol research.

    Science.gov (United States)

    Castro, Felipe Gonzalez; Barrera, Manuel; Mena, Laura A; Aguirre, Katherine M

    2014-01-01

    For the period of almost 75 years, we examined the literature for studies regarding the influences of culture on alcohol use and misuse. This review is a chronology of research articles published from 1940 to 2013. From a structured literature search with select criteria, 38 articles were identified and 34 reviewed. This analysis revealed a progression across this period of research from studies that began as descriptive ethnographic evaluations of one or more indigenous societies or cultural groups, evolving to studies using complex multivariate models to test cross-cultural effects in two or more cultural groups. Major findings across this period include the assertions that (a) a function of alcohol use may be to reduce anxiety, (b) certain cultural groups possess features of alcohol use that are not associated with negative consequences, (c) the disruptive effects of acculturative change and the stressors of new demands are associated with an increase in alcohol consumption, (d) cultural groups shape expectations about the effects of alcohol use and their definition of drunkenness, and (e) the hypothesized relationships of culture with alcohol use and misuse have been demonstrated in multivariate model analyses. Across this 75-year period, the early proposition that culture is an important and prominent correlate of alcohol use and misuse has persisted. Within the current era of alcohol studies, this proposition has been supported by multivariate model analyses. Thus, the proposition that culture might affect alcohol use remains prominent and is as relevant today as it was when it was first proposed nearly 75 years ago.

  4. Profile of Students’ Critical Thinking Skill Measured by Science Virtual Test on Living Things and Environmental Sustainability Theme

    Science.gov (United States)

    Maulida, N. I.; Firman, H.; Rusyati, L.

    2017-02-01

    The aims of this study are: (1) to investigate the level of students’ critical thinking skill on living things and environmental sustainability theme for each Inch’ critical thinking elements and overall, (2) to investigate the level of students’ critical thinking skill on living things characteristic, biodiversity, energy resources, ecosystem, environmental pollution, and global warming topics. The research was conducted due to the important of critical thinking measurement to get the current skill description as the basic consideration for further critical thinking skill improvement in lower secondary science. The research method used was descriptive. 331 seventh grade students taken from five lower secondary schools in Cirebon were tested to get the critical thinking skill data by using Science Virtual Test as the instrument. Generally, the mean scores on eight Inch’ critical thinking elements and overall score from descriptive statistic reveals a moderate attainments level. Students’ critical thinking skill on biodiversity, energy resources, ecosystem, environmental pollution, and global warming topics are in moderate level. While students’ critical thinking skill on living things characteristic is identified as high level. Students’ experience in thinking critically during science learning process and the characteristic of the topic are emerged as the reason behind the students’ critical thinking skill level on certain science topic.

  5. Technological integration in Brazilian public basic education: an analysis of the temporal evolution and the interdisciplinarity of the theme

    Directory of Open Access Journals (Sweden)

    Priscila Cadorin Nicolete

    2016-12-01

    Full Text Available The complexity inherent to technological integration in the context of basic education in the current reality of the students and the digital culture that permeates society today features a transformation in the dynamics of knowledge construction. It is difficult to connect students, fully involving them in this process when using traditional teaching and learning methods. This new context requires interdisciplinary research for better understanding, involving experts in the field of sciences and more technical areas such as engineering and computer science. To answer the question of how to handle the evolution of interdisciplinary theoretical and empirical studies related to the subject, it was developed a survey in order to understand the evolution, interdisciplinarity and the theoretical and empirical variables related to the integration of technologies in the Brazilian basic education. This article presents the results of the exploratory survey of systematic review procedures of literature in electronic databases, then bibliometric and descriptive analyzes. Among the obtained results, were identified as strategies for the integration of technologies in Brazilian public basic education: Remote Experimentation for Physics, Mobile Learning and Software teaching for practices in Mathematics classes. The studies are divided into six large areas of knowledge: Social Sciences, Decision Science, Computer Science, Engineering, Business and Mathematics, demonstrating the interdisciplinarity of the theme.

  6. Major Depressive Disorder

    Directory of Open Access Journals (Sweden)

    G Grobler

    2013-08-01

    Full Text Available The treatment guideline draws on several international guidelines: (iPractice Guidelines of the American Psychiatric Association (APAfor the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii Clinical Guidelines for the Treatment of DepressiveDisorders by the Canadian Psychiatric Association and the CanadianNetwork for Mood and Anxiety Treatments (CANMAT;[2](iiiNational Institute for Clinical Excellence (NICE guidelines;[3](iv RoyalAustralian and New Zealand College of Psychiatrists Clinical PracticeGuidelines Team for Depression (RANZCAP;[4](v Texas MedicationAlgorithm Project (TMAP Guidelines;[5](vi World Federation ofSocieties of Biological Psychiatry (WFSBP Treatment Guideline forUnipolar Depressive Disorder;[6]and (vii British Association forPsychopharmacology Guidelines.[7

  7. [The most cited themes in the research in the field of Mental Health: analyses of six international nursing and medical journals].

    Science.gov (United States)

    Cunico, Laura; Fredo, Susanna; Bernini, Massimo

    2017-01-01

    The review aimed to identify and analyse the future development on the topic by analysing the main themes discussed in number of scientific journal focused on Mental Health both by nurses and physicians.. 4 international journals focused on Mental health and psychiatry International Journal of Mental Health Nursing, Archives of Psychiatric Nursing, American Journal of Psychiatry, Australian and New Zeland Journal of Psychiatry as well as two journal focused generically on health, Journal of Advanced Nursing and Lancet were scrutinized. We have analysed the papers of 2012-2015 for the specialised journals and last and first 6 months of 2012 and 2013 and 2014-2015 for the generic. Editorials, comments and contributions regarding theoretical models were exluded. From the analysis we identified 9 themes and for each theme the pertinent category. For the diagnostic grouping we used the International Statistical Classification of Diseases and Related Health Problems 10th Revision. A trend in research about mood disorders, schizophrenia and addictions and comorbidity emerged according to the 2099 abstracts analysed. Within medical research antidepressants were the most studied psychotropic medication and cognitive behaviour therapy was the most studied psychotherapy. Within nursing research: the nurse-patient relationship, adherence and monitoring of pharmacological therapy, the treatment planning and the working environment, the nursing training and its efficacy. The clinical research trials were twice as frequent in the medical versus nursing research where qualitative research prevails. The research challenge will be to find a new paradigm fit for the future psychiatry having at its disposition the patient's genoma, and needing to routinely use biomarkers for a personalised therapy. A further challenge might be the promotion of interprofessional research between doctors and nurses and the acquisition of new competences of health professionals needed to tackle the

  8. Proceedings of the DAE-BRNS theme meeting on advanced chemical sensors and their applications: book of abstracts

    International Nuclear Information System (INIS)

    2012-01-01

    DAE-BRNS theme meeting on advanced chemical sensors and their applications was focussed on chemical sensors for nuclear applications, sensors for environmental and biological systems applications, materials development for sensors applications. Papers relevant to INIS are indexed separately

  9. Perspectives of Employees with Intellectual Disabilities on Themes Relevant to Their Job Satisfaction. An Explorative Study using Photovoice

    NARCIS (Netherlands)

    Akkerman, A.; Janssen, C.G.C.; Kef, S.; Meininger, H.P.

    2014-01-01

    Background: This study explored the perspectives of people with intellectual disabilities on themes relevant to their job satisfaction in integrated and sheltered employment. Method: The photovoice method was used. Nine participants with moderate to mild intellectual disabilities, working in

  10. Theme--Achieving 2020. Goal 3: All Students Are Conversationally Literate in Agriculture, Food, Fiber, and Natural Resource Systems.

    Science.gov (United States)

    Trexler, Cary, Ed.

    2000-01-01

    Nine theme articles focus on the need for students to be conversationally literate about agriculture, food, fiber, and natural resources systems. Discusses the definition of conversational literacy, the human and institutional resources needed, and exemplary models for promoting literacy. (JOW)

  11. Generation of Variations on Theme Music Based on Impressions of Story Scenes Considering Human's Feeling of Music and Stories

    Directory of Open Access Journals (Sweden)

    Kenkichi Ishizuka

    2008-01-01

    Full Text Available This paper describes a system which generates variations on theme music fitting to story scenes represented by texts and/or pictures. Inputs to the present system are original theme music and numerical information on given story scenes. The present system varies melodies, tempos, tones, tonalities, and accompaniments of given theme music based on impressions of story scenes. Genetic algorithms (GAs using modular neural network (MNN models as fitness functions are applied to music generation in order to reflect user's feeling of music and stories. The present system adjusts MNN models for each user on line. This paper also describes the evaluation experiments to confirm whether the generated variations on theme music reflect impressions of story scenes appropriately or not.

  12. Evaluation of a webquest on the theme "management of material resources in nursing" by undergraduate students.

    Science.gov (United States)

    Pereira, Marta Cristiane Alves; Melo, Márcia Regina Antonietto da Costa; Silva, Adriana Serafim Bispo E; Evora, Yolanda Dora Martinez

    2010-01-01

    The learning process mediated by information and communication technology has considerable importance in the current context. This study describes the evaluation of a WebQuest on the theme "Management of Material Resources in Nursing". It was developed in three stages: Stage 1 consisted of its pedagogical aspect, that is, elaboration and definition of content; Stage 2 involved the organization of content, inclusion of images and completion; Stage 3 corresponded to its availability to students. Results confirm the importance of information technology and information as instruments for a mediating teaching practice in the integration between valid knowledge and the complex and dynamic reality of health services. As a result of the students' favorable evaluation of the approximation with the reality of nursing work and satisfaction for performing the activity successfully, the WebQuest method was considered valid and innovating for the teaching-learning process.

  13. The theme of love in Henrik Pontoppidan's Nattevagt (Night Watch) and other short novels

    DEFF Research Database (Denmark)

    Gammelgård, Judy

    2007-01-01

    The subject of love may not seem an appropriate topic of scientific discourse, for we prefer turning to poetry to learn something meaningsful about love. Nontheless, we find three texts on the subject in Freud´s work, all of which underline an internal division in love. He discussed the contrast...... of the 19th century. He is well-known for his novels and short novels. One of these, Nattevagt, from 1894, has been read by critics as a marital conflict between the painter Jørgen Hallager and his fragile wife Ursula Branth, who succumbs to the brutality of her husband. The author supplements this simple...... version of the story with aspects made visible through the idea of an internal division in sexuality, which Freud elaborated into his theory of the death drive around 1920. By way of introduction, a few words are said about Pontoppidan, focusing on the theme of love in his short novels. Following...

  14. City and labyrinth: Theme and variation in Calvino and Duranti’s cityscapes

    Directory of Open Access Journals (Sweden)

    R. Wilson

    1992-05-01

    Full Text Available For a number of Italian writers the modem city has come to mean as much a style, a fractured syntax, a paratactic sign-system, as a physical construct with certain demonstrable boundaries. In the works of such authors as halo Calvino and Francesca Duranti the crisis of reason is symbolized by indeterminate aleatory structures - such as the labyrinth or the chessboard - all of which can be considered variations on the theme of the modem city. Calvino and Duranti’s invisible or labyrinthine cities serve as an infinitely malleable poetic dramatization of the mind. The cities are both projections of their respective narrators and images that shape the reader's experience. By analysing the spatial structures of the narratives and by examining the use of space as a locus of fantasy this article shows how these novels chart cityscapes of the mind.

  15. From The Human-Environment Theme Towards Sustainability – Danish Geography and Education for Sustainable Development

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou

    2013-01-01

    Research on geography in relation to education for sustainable development (ESD), has only recently climbed the research agenda. The geopolitics of intended learning outcomes in the ESD debate, carries policy that produce dilemmas and challenges confronted with disciplinary traditions....... In this article it is examined dialectically how the changing climate and the paradigm of sustainability have been dealt with in Danish geographical university education. It is shown how curriculum programs in higher geographical education have taken different approaches to address issues of sustainability...... and climate change and how geographers articulate their role and function as knowledge on human-environment interactions changes. The analysis of the geographical education reveal that geographers’ find their discipline contribute considerably to ESD, and thus the human environment theme seems...

  16. The Consensus of Strategic Consensus: A Study of the State of the Art about the Theme

    Directory of Open Access Journals (Sweden)

    Marcelo Curth

    2018-04-01

    Full Text Available This paper aims to present the state of the art regarding the strategic consensus, emphasizing the approaches and the nature of the research methods used, the results obtained and the future agenda for this theme studies. Analyzing beyond the last four decades of publications, it was understood that relating the strategic consensus only with the performance and strategic levels can be seen as something limited, suggesting the need to bring to the researching field new aspects and backgrounds as innovation, the methods for generating new ideas, the occurrence beyond the Top Management Team level (TMT, among others. Moreover, concludes that the predominant approach the strategic consensus is a process and the methodology used is based on quantitative techniques. As a suggestion for future studies, this study indicates the investigation of situations in which the strategic consensus is not positive.

  17. Fernando Arrabal's "Ars Amandi": The Theme of Love in Selected Plays

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    Peter L. Podol

    1977-09-01

    Full Text Available The evolution in Arrabal's treatment of the theme of love reflects both the development and enrichment of his dramatic techniques and the resolution of his own deep-seated psychological conflicts. Arrabal's theater utilizes his concept of dramatic ceremony to project his intense desire for personal, political and artistic liberation. Psychological and social forces combine to frustrate the fulfillment of love in his early theater ( Fando and Lis , 1956 but ultimately love functions to obviate both internal and external constraints. Sexual union, which receives its most rapturous affirmation in Arrabal's plays written during the late 1960's ( The Law of Barabbas , Ars Amandi , and Erotic Bestiality , reflects the reconciliation of dialectical forces present in man's psyche. Women come to serve as intermediaries between man and the world. And in the broadest sense, the dramatic structure of Arrabal's mature plays can be depicted as the movement from psychic fragmentation to psychic unity, effected by the force of love.

  18. The Concept Maps as a Didactic Resource Tool of Meaningful Learning in Astronomy Themes

    Science.gov (United States)

    Silveira, Felipa Pacífico Ribeiro de Assis; Mendonça, Conceição Aparecida Soares

    2015-07-01

    This article presents the results of an investigation that sought to understand the performance of the conceptual map (MC) as a teaching resource facilitator of meaningful learning of scientific concepts on astronomical themes, developed with elementary school students. The methodology employed to obtain and process the data was based on a quantitative and qualitative approach. On the quantitative level we designed a quasi-experimental research with a control group that did not use the MC and an experimental group that used the MC, both being evaluated in the beginning and end of the process. In this case, the performance of both groups is displayed in a descriptive and analytical study. In the qualitative approach, the MCs were interpreted using the structuring and assigned meanings shared by the student during his/her presentation. The results demonstrated through the improvement of qualifications that the MC made a difference in conceptual learning and in certain skills revealed by learning indicators.

  19. Attitudinal effects of degrading themes and sexual explicitness in video materials.

    Science.gov (United States)

    Golde, J A; Strassberg, D S; Turner, C M; Lowe, K

    2000-07-01

    This study examined the independent and interactive effects of sexual explicitness and degrading themes toward women on mens' attitudes following exposure to video presentations of male-female interactions. Subjects were 83 male college students who viewed video vignettes under one of four stimulus conditions: (a) sexually explicit/degrading, (b) sexually explicit/nondegrading, (c) nonexplicit/degrading, and (d) nonexplicit/nondegrading. Results revealed that men exposed to degrading material, regardless of explicitness, were significantly more likely to express attitudes supportive of rape, while explicitness had no significant main or interactive effect on these attitudes. Further, the interaction of explicitness with degradation was found to impact scores on a measure of sexual callousness. Theoretical and clinical implications of these findings are discussed.

  20. More than Just a Game? Combat-Themed Gaming Among Recent Veterans with Posttraumatic Stress Disorder.

    Science.gov (United States)

    Elliott, Luther; Golub, Andrew; Price, Matthew; Bennett, Alexander

    2015-08-01

    This article examines recent combat veterans' experiences of "first-person shooter" (FPS) gaming and its relationship to posttraumatic stress disorder (PTSD). Current PTSD treatment approaches increasingly use virtual reality (VR) technologies, which have many similarities with FPS games. To explore these similarities, this article presents six case studies from recently separated veterans in New York City who reported both current PTSD symptoms and regular use of combat-themed FPS games. In open-ended interviews, participants discussed a range of benefits as well as the importance of regulating use and avoiding particular contextual dimensions of gaming to maintain healthy gaming habits. Findings demonstrate the need for more comprehensive study and dissemination of best-practices information about FPS gaming in the context of combat-related PTSD symptomatology.