WorldWideScience

Sample records for identify key issues

  1. Key Research Issues in Clostridium difficile

    Directory of Open Access Journals (Sweden)

    George Zhanel

    2005-01-01

    Full Text Available Clostridium difficile is an emerging pathogen that causes C difficile-associated diarrhea, an important nosocomial infection. Control of this infection remains a challenge, and much needs to be determined about the antimicrobial resistance of the organism, antibiotic stewardship, contamination of the patient environment, and various host factors that determine susceptibility or resistance to infection. A national symposium focusing on C difficile infections, the Clostridium difficile Symposium on Emerging Issues and Research, was hosted on November 23, 2004, by the Department of Medical Microbiology and Infectious Diseases at the University of Manitoba, Winnipeg, Manitoba, in partnership with the Canadian Institutes of Health Research. This symposium, which aimed to summarize key research issues regarding C difficile infections in Canada, had the following objectives: to provide a forum for learning and discussion about C difficile and its impact on the health of Canadians; to identify the key research issues that should be addressed; and to explore potential research funding opportunities and collaboration. The present report summarizes key research issues identified for C difficile infections in Canada by addressing four major themes: diagnosis and surveillance, infection prevention and control, antibiotic stewardship, and clinical management.

  2. An approach to identify issues affecting ERP implementation in Indian SMEs

    Directory of Open Access Journals (Sweden)

    Rana Basu

    2012-06-01

    Full Text Available Purpose: The purpose of this paper is to present the findings of a study which is based on the results of a comprehensive compilation of literature and subsequent analysis of ERP implementation success issues in context to Indian Small and Medium scale Enterprises (SME’s. This paper attempts to explore the existing literature and highlight those issues on ERP implementation and further to this the researchers applied TOPSIS (Technique for order preference by similarity to ideal solution method to prioritize issues affecting successful implementation of ERP. Design/methodology/approach: Based on the literature review certain issues leading to successful ERP implementation have been identified and to identify key issues Pareto Analysis (80-20 Rule have been applied. Further to extraction of key issues a survey based on TOPSIS was carried out in Indian small and medium scale enterprises. Findings: Based on review of literature 25 issues have been identified and further Pareto analysis has been done to extract key issues which is further prioritized by applying Topsis method. Research limitations/implications: Beside those identified issues there may be other issues that need to be explored. There is scope to enhance this study by taking into consideration different type of industries and by extending number of respondents. Practical implications: By identifying key issues for SMEs, managers can better prioritize issues to make implementation process smooth without disruption. ERP vendors can take inputs from this study to change their implementation approach while targeting small scale enterprises. Originality/value: There is no published literature available which followed a similar approach in identification of the critical issues affecting ERP in small and mid-sized companies in India or in any developing economy.

  3. Key Issues in Empirically Identifying Chronically Low-Performing and Turnaround Schools

    Science.gov (United States)

    Hansen, Michael

    2012-01-01

    One of the US Department of Education's key priorities is turning around the nation's persistently low-achieving schools, yet exactly how to identify low-performing schools is a task left to state policy makers, and a myriad of definitions have been utilized. In addition, exactly how to recognize when a school begins to turn around is not well…

  4. Low carbon development. Key issues

    Energy Technology Data Exchange (ETDEWEB)

    Urban, Frauke; Nordensvaard, Johan (eds.)

    2013-03-07

    This comprehensive textbook addresses the interface between international development and climate change in a carbon constrained world. It discusses the key conceptual, empirical and policy-related issues of low carbon development and takes an international and interdisciplinary approach to the subject by drawing on insights from across the natural sciences and social sciences whilst embedding the discussion in a global context. The first part explores the concept of low carbon development and explains the need for low carbon development in a carbon constrained world. The book then discusses the key issues of socio-economic, political and technological nature for low carbon development, exploring topics such as the political economy, social justice, financing and carbon markets, and technologies and innovation for low carbon development. This is followed by key issues for low carbon development in policy and practice, which is presented based on cross-cutting issues such as low carbon energy, forestry, agriculture and transportation. Afterwards, practical case studies are discussed from low carbon development in low income countries in Africa, middle income countries in Asia and Latin America and high income countries in Europe and North America.

  5. Identifying tier one key suppliers.

    Science.gov (United States)

    Wicks, Steve

    2013-01-01

    In today's global marketplace, businesses are becoming increasingly reliant on suppliers for the provision of key processes, activities, products and services in support of their strategic business goals. The result is that now, more than ever, the failure of a key supplier has potential to damage reputation, productivity, compliance and financial performance seriously. Yet despite this, there is no recognised standard or guidance for identifying a tier one key supplier base and, up to now, there has been little or no research on how to do so effectively. This paper outlines the key findings of a BCI-sponsored research project to investigate good practice in identifying tier one key suppliers, and suggests a scalable framework process model and risk matrix tool to help businesses effectively identify their tier one key supplier base.

  6. Key issues

    International Nuclear Information System (INIS)

    Cook, N.G.W.

    1980-01-01

    Successful modeling of the thermo-mechanical and hydrochemical behavior of radioactive waste repositories in hard rock is possible in principle. Because such predictions lie outside the realm of experience, their adequacy depends entirely upon a thorough understanding of three fundamental questions: an understanding of the chemical and physical processess that determine the behavior of rock and all its complexities; accurate and realistic numerical models of the geologic media within which a repository may be built; and sufficient in-situ data covering the entire geologic region affected by, or effecting the behavior of a repository. At present sufficient is known to be able to identify most of those areas which require further attention. These areas extend all the way from a complete understanding of the chemical and physical processes determining the behavior of rock through to the exploration mapping and testing that must be done during the development of any potential repository. Many of the techniques, laboratory equipment, field instrumentation, and numerical methods needed to accomplish this do not exist at present. Therefore it is necessary to accept that a major investment in scientific research is required to generate this information over the next few years. The spectrum of scientific and engineering activities is wide extending from laboratory measurements through the development of numerical models to the measurement of data in-situ, but there is every prospect that sufficient can be done to resolve these key issues. However, to do so requires overt recognition of the many gaps which exist in our knowledge and abilities today, and of the need to bridge these gaps and of the significant costs involved in doing so

  7. Decommissioning: Regulatory activities and identification of key organizational and human factors safety issues

    International Nuclear Information System (INIS)

    Durbin, N.E.; Melber, B.D.; Lekberg, A.

    2001-12-01

    In the late 1990's the Swedish government decided to shut down Unit 1 of the Barsebaeck nuclear power plant. This report documents some of the efforts made by the Swedish Nuclear Power Inspectorate (SKI) to address human factors and organizational issues in nuclear safety during decommissioning of a nuclear facility. This report gives a brief review of the background to the decommissioning of Barsebaeck 1 and points out key safety issues that can arise during decommissioning. The main regulatory activities that were undertaken were requirements that the plant provide special safety reports on decommissioning focusing on first, the operation of both units until closure of Unit 1 and second, the operation of Unit 2 when Unit 1 was closed. In addition, SKI identified areas that might be affected by decommissioning and called these areas out for special attention. With regard to these areas of special attention, SKI required that the plant provide monthly reports on changing and emerging issues as well as self-assessments of the areas to be addressed in the special safety reports. Ten key safety issues were identified and evaluated with regard to different stages of decommissioning and with regard to the actions taken by Barsebaeck. Some key conclusions from SKI's experience in regulating a decommissioning nuclear power plant conclude the report

  8. Key Health Information Technologies and Related Issues for Iran: A Qualitative Study.

    Science.gov (United States)

    Hemmat, Morteza; Ayatollahi, Haleh; Maleki, Mohammadreza; Saghafi, Fatemeh

    2018-01-01

    Planning for the future of Health Information Technology (HIT) requires applying a systematic approach when conducting foresight studies. The aim of this study was to identify key health information technologies and related issues for Iran until 2025. This was a qualitative study and the participants included experts and policy makers in the field of health information technology. In-depth semi-structured interviews were conducted and data were analyzed by using framework analysis and MAXQDA software. The findings revealed that the development of national health information network, electronic health records, patient health records, a cloud-based service center, interoperability standards, patient monitoring technologies, telehealth, mhealth, clinical decision support systems, health information technology and mhealth infrastructure were found to be the key technologies for the future. These technologies could influence the economic, organizational and individual levels. To achieve them, the economic and organizational obstacles need to be overcome. In this study, a number of key technologies and related issues were identified. This approach can help to focus on the most important technologies in the future and to priorities these technologies for better resource allocation and policy making.

  9. Identification and Characterization of Key Human Performance Issues and Research in the Next Generation Air Transportation System (NextGen)

    Science.gov (United States)

    Lee, Paul U.; Sheridan, Tom; Poage, james L.; Martin, Lynne Hazel; Jobe, Kimberly K.

    2010-01-01

    This report identifies key human-performance-related issues associated with Next Generation Air Transportation System (NextGen) research in the NASA NextGen-Airspace Project. Four Research Focus Areas (RFAs) in the NextGen-Airspace Project - namely Separation Assurance (SA), Airspace Super Density Operations (ASDO), Traffic Flow Management (TFM), and Dynamic Airspace Configuration (DAC) - were examined closely. In the course of the research, it was determined that the identified human performance issues needed to be analyzed in the context of NextGen operations rather than through basic human factors research. The main gaps in human factors research in NextGen were found in the need for accurate identification of key human-systems related issues within the context of specific NextGen concepts and better design of the operational requirements for those concepts. By focusing on human-system related issues for individual concepts, key human performance issues for the four RFAs were identified and described in this report. In addition, mixed equipage airspace with components of two RFAs were characterized to illustrate potential human performance issues that arise from the integration of multiple concepts.

  10. Emergency management in health: key issues and challenges in the UK.

    Science.gov (United States)

    Lee, Andrew C K; Phillips, Wendy; Challen, Kirsty; Goodacre, Steve

    2012-10-19

    Emergency planning in the UK has grown considerably in recent years, galvanised by the threat of terrorism. However, deficiencies in NHS emergency planning were identified and the evidence-base that underpins it is questionable. Inconsistencies in terminologies and concepts also exist. Different models of emergency management exist internationally but the optimal system is unknown. This study examines the evidence-base and evidence requirements for emergency planning in the UK health context. The study involved semi-structured interviews with key stakeholders and opinion leaders. Purposive sampling was used to obtain a breadth of views from various agencies involved in emergency planning and response. Interviews were then analysed using a grounded approach using standard framework analysis techniques. We conducted 17 key informant interviews. Interviewees identified greater gaps in operational than technical aspects of emergency planning. Social and behavioural knowledge gaps were highlighted with regards to how individuals and organisations deal with risk and behave in emergencies. Evidence-based approaches to public engagement and for developing community resilience to disasters are lacking. Other gaps included how knowledge was developed and used. Conflicting views with regards to the optimal configuration and operation of the emergency management system were voiced. Four thematic categories for future research emerged:(i) Knowledge-base for emergency management: Further exploration is needed of how knowledge is acquired, valued, disseminated, adopted and retained.(ii) Social and behavioural issues: Greater understanding of how individuals approach risk and behave in emergencies is required.(iii) Organisational issues in emergencies: Several conflicting organisational issues were identified; value of planning versus plans, flexible versus standardized procedures, top-down versus bottom-up engagement, generic versus specific planning, and reactive versus

  11. Key issues for passive safety

    International Nuclear Information System (INIS)

    Hayns, M.R.

    1996-01-01

    The paper represents a summary of the introductory presentation made at this Advisory Group Meeting on the Technical Feasibility and Reliability of Passive Safety Systems. It was intended as an overview of our views on what are the key issues and what are the technical problems which might dominate any future developments of passive safety systems. It is, therefore, not a ''review paper'' as such and only record the highlights. (author)

  12. Key issues for passive safety

    Energy Technology Data Exchange (ETDEWEB)

    Hayns, M R [AEA Technology, Harwell, Didcot (United Kingdom). European Institutions; Hicken, E F [Forschungszentrum Juelich GmbH (Germany)

    1996-12-01

    The paper represents a summary of the introductory presentation made at this Advisory Group Meeting on the Technical Feasibility and Reliability of Passive Safety Systems. It was intended as an overview of our views on what are the key issues and what are the technical problems which might dominate any future developments of passive safety systems. It is, therefore, not a ``review paper`` as such and only record the highlights. (author).

  13. Information Systems Management: an Australian view of the key issues

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1994-05-01

    Full Text Available Studies investigating the key issues in IS management serve to better understand the concerns of IS managers and help to guide IS researchers in choosing IS management problems worthy of investigation. This paper presents results from a study of the key issues facing the IS managers of Australia's largest 300 organisations which is part of a three-yearly longitudinal study. In order to gain consensus on the relative importance of the key issues, a three-round Delphi method was applied. The results reveal that IS strategic planning continues to be the paramount issue in our industry, as are many issues associated with IS strategic planning, including responsiveness of the IT infrastructure, effective use of the data resource, IS for competitive advantage, and a comprehensive information architecture. A greater emphasis on quality is also revealed in highly rated issues such as effective use of the data resource, data integrity and quality assurance, and the quality of software development

  14. Dating Violence among College Students: Key Issues for College Counselors

    Science.gov (United States)

    Murray, Christine E.; Kardatzke, Kerrie N.

    2007-01-01

    The authors present a review of literature examining dating violence among college students. They describe 6 key issues related to dating violence among college students that affect college counselors' work. These key issues relate to the incidence and prevalence of physical, sexual, and psychological violence in college students' dating…

  15. Key management issue in SCADA networks: A review

    Directory of Open Access Journals (Sweden)

    Abdalhossein Rezai

    2017-02-01

    Full Text Available Supervisory Control And Data Acquisition (SCADA networks have a vital role in Critical Infrastructures (CIs such as public transports, power generation systems, gas, water and oil industries, so that there are concerns on security issues in these networks. The utilized Remote Terminal Units (RTUs and Intelligence Electronic Devices (IEDs in these networks have resource limitations, which make security applications a challenging issue. Efficient key management schemes are required besides lightweight ciphers for securing the SCADA communications. Many key management schemes have been developed to address the tradeoff between SCADA constrain and security, but which scheme is the most effective is still debatable. This paper presents a review of the existing key management schemes in SCADA networks, which provides directions for further researches in this field.

  16. Towards optimised information about clinical trials; identification and validation of key issues in collaboration with cancer patient advocates

    DEFF Research Database (Denmark)

    Dellson, P; Nilbert, M; Bendahl, P-O

    2011-01-01

    for improvements, 21 key issues were defined and validated through a questionnaire in an independent group of breast cancer patient advocates. Clear messages, emotionally neutral expressions, careful descriptions of side effects, clear comparisons between different treatment alternatives and information about......Clinical trials are crucial to improve cancer treatment but recruitment is difficult. Optimised patient information has been recognised as a key issue. In line with the increasing focus on patients' perspectives in health care, we aimed to study patients' opinions about the written information used...... the possibility to discontinue treatment were perceived as the most important issues. Patients' views of the information in clinical trials provide new insights and identify key issues to consider in optimising future written information and may improve recruitment to clinical cancer trials....

  17. Towards optimised information about clinical trials; identification and validation of key issues in collaboration with cancer patient advocates.

    Science.gov (United States)

    Dellson, P; Nilbert, M; Bendahl, P-O; Malmström, P; Carlsson, C

    2011-07-01

    Clinical trials are crucial to improve cancer treatment but recruitment is difficult. Optimised patient information has been recognised as a key issue. In line with the increasing focus on patients' perspectives in health care, we aimed to study patients' opinions about the written information used in three clinical trials for breast cancer. Primary data collection was done in focus group interviews with breast cancer patient advocates. Content analysis identified three major themes: comprehensibility, emotions and associations, and decision making. Based on the advocates' suggestions for improvements, 21 key issues were defined and validated through a questionnaire in an independent group of breast cancer patient advocates. Clear messages, emotionally neutral expressions, careful descriptions of side effects, clear comparisons between different treatment alternatives and information about the possibility to discontinue treatment were perceived as the most important issues. Patients' views of the information in clinical trials provide new insights and identify key issues to consider in optimising future written information and may improve recruitment to clinical cancer trials. © 2010 Blackwell Publishing Ltd.

  18. Identification of Key Issues in Adopting a Web 2.0 E-Portfolio Strategy

    Science.gov (United States)

    McKenna, Gary F.; Stansfield, Mark H.

    2013-01-01

    The purpose of the paper is to identify key issues relating to best practice and sustainability in Web 2.0 as an e-Learning strategy for supporting e-portfolios in Higher Education. A practical guidelines framework was developed for best practices, which can be justified by the lack of available frameworks in the e-Learning literature. A…

  19. EDITORIAL: 'Key issues' articles in Reports on Progress in Physics

    Science.gov (United States)

    Greene, Laura H.

    2007-03-01

    The Editorial Board of Reports on Progress in Physics has commissioned a series of short articles from world leaders on key physics issues in their field. These essays may raise the key issues, or ask open questions or may even suggest wild ideas. Basically, they give world leading physicists the opportunity to write what they think about the key issues in their field, free from the usual requirement to provide the fair and balanced presentations of the subject normally found in articles in Reports on Progress in Physics. We believe that the readers of the journal will be interested to learn about these exciting ideas. Just as Hilbert's famous paper of 1900 set the agenda for the next century or more in mathematics, so we hope that this series of papers will define the key issues and open questions in physics for the 21st Century and that the articles will be widely cited and downloaded. The first of these articles—'Insights from simulations of star formation' by Richard B Larson (Yale University, USA)—is published in the current issue. We trust that readers will find this article and its successors in the series to appear through 2007 and beyond entertaining and stimulating.

  20. Information Systems Management: an Australasian view of key issues - 1996

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1997-11-01

    Full Text Available As part of a longitudinal study of key information systems management issues, a survey of Australasia's largest 500 organisations was conducted to identify which issues were perceived by the IS executives as being important, problematic and critical over the next three to five years. The most critical issues were revealed to be a mix of technology management issues (IT infrastructure, communications, disaster recovery, strategic management issues (competitive advantage, IS planning, aligning the IS organisation, people management issues (organisational learning, educating senior management in IT, systems development and data management issues (effective use of the data resource, and end-user computing. This reflects the need for a balance of business, technical, and people skills in an IS executive. Non-critical issues were mostly related to systems development and the individual technologies which must be integrated and managed to ensure a responsive IT infrastructure. The study also reveals that some issues are much more important than problematic (disaster recovery, competitive advantage, information architecture, and IS alignment while others are much more problematic than important (end-user computing, IS role and contribution, and BPR. The former reflects a growing level of knowledge in handling these issues, while the latter reflects a continuing problem with them. The differences between this study and similar studies conducted in 1988 and 1992 show that there is a growing confidence in the IS executive's ability to manage the strategic issues, a continuing concern about providing a responsive IT infrastructure (especially communications, and a continuing concern with educating all 'customers' in the organisation in the effective use of IT, including senior management.

  1. Key issues for the control of refueling outage duration and costs in PWR nuclear power plants

    International Nuclear Information System (INIS)

    Degrave, C.; Martin-Onraet, M.

    2000-01-01

    For several years, EDF, within the framework of the CIDEM project and in collaboration with some German Utilities, has undertaken a detailed review of the operating experience both of its own NPP and of foreign units, in order to improve the performances of future units under design, particularly the French-German European Pressurized Reactor (EPR) project. This review made it possible to identify the key issues allowing to decrease the duration of refueling and maintenance outages. These key issues can be classified in 3 categories: Design; Maintenance and Logistic Support; Outage Management. Most key issues in the design field and some in the logistic support field have been studied and could be integrated into the design of any future PWR unit, as for the EPR project. Some of them could also be adapted to current plants, provided they are feasible and profitable. The organization must be tailored to each country, utility or period: it widely depends on the power production environment, particularly in a deregulation context. (author)

  2. A CEO View of Key Issues in Australian Information Systems Management - 1997

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1998-05-01

    Full Text Available As part of a research programme on key information systems management issues, a survey of Australasia's largest 500 organisations was conducted to identify which issues were perceived by their chief executive officers (CEOs as being important, problematic and critical over the next three to five years. The results reported are based on a relatively low response rate (though perhaps reasonable for the target group so should be regarded as only exploratory. The most critical issues were revealed to be a mix of technology management issues (IT infrastructure, disaster recovery, strategic management issues (BPR, competitive advantage, information architecture, people management issues (organisational learning, systems development and data management issues (effective use of the data resource, effectiveness/productivity of IS, effectiveness of software development, and their own support systems (EIS/DSS. This reflects their interest in a wide range of issues, but all with an organisation-wide focus. Non-critical issues were mostly related to the individual technologies and the place and role of IS in the organisation. While the CEOs showed some agreement with their chief information officers (CIOs on issues such as the IT infrastructure, competitive advantage, and organisational learning some distinct differences exist, particularly in relation to the quality and effectiveness of systems and processes and also how CEOs and CIOs perceive each other.

  3. Key Issues for the control of refueling outage duration and costs in PWR Nuclear Power Plants

    International Nuclear Information System (INIS)

    Degrave, Claude

    2002-01-01

    For several years, EDF, within the framework of the CIDEM1 project and in collaboration with some German Utilities, has undertaken a detailed review of the operating experience both of its own NPP and of foreign units, in order to improve the performances of future units under design, particularly the French-German European Pressurized Reactor (EPR) project. This review made it possible to identify the key issues allowing to decrease the duration of refueling and maintenance outages. These key issues can be classified in 3 categories Design, Maintenance and Logistic Support, Outage Management. Most of the key issues in the design field and some in the logistic support field have been studied and could be integrated into the design of any future PWR unit, as for the EPR project. Some of them could also be adapted to current plants, provided they are feasible and profitable. The organization must be tailored to each country, utility or period: it widely depends on the power production environment, particularly in a deregulation context. (author)

  4. A scoping review identifying contemporary issues in rural nursing leadership.

    Science.gov (United States)

    Bish, Melanie; Kenny, Amanda; Nay, Rhonda

    2012-12-01

    Rural nurse leaders on a global scale are being challenged to create structures and processes to enable excellence in nursing care. The purpose of this scoping review is to offer an indication of the available literature relating to contemporary issues in rural nursing leadership. A review of contemporary issues facing rural nurse leaders is timely to assist strategy development that will achieve the goal of excellence in nursing. An interpretative scoping literature review methodological framework has been used with an emphasis on thematic construction. Literature published between 2008 and 2012 was reviewed from five electronic databases using the key words rural, nursing, and leadership. Four themes have been identified: expectations of rural nursing leadership, a highly educated workforce, competing interests, and partnering within rural healthcare systems. The content may resonate with rural nurse leaders and encourage a greater awareness of their relevance to leadership practices. The findings provide a greater awareness and understanding of contemporary issues facing rural nurse leaders and may assist with the development of context-sensitive leadership strategies to facilitate excellence in nursing care. © 2012 Sigma Theta Tau International.

  5. BENTO buffer development program in Finland - Key issues

    International Nuclear Information System (INIS)

    Autio, J.; Korkiala-Tanttu, L.; Vaehaenen, M.; Koskinen, K.; Korkeakoski, P.; Haapala, K.

    2010-01-01

    key project in the programme. Another key part of development is the manufacturing of buffer components (MANU project), which is responsible of the manufacturing of buffer components for testing and final use in the repository. MANU covers the whole chain of events from raw material acquisition and management to manufacturing and emplacement of the final bentonite products. The development of design and manufacturing requires significant amount of research in order to define the processes that take place during buffer's lifespan from manufacturing to actual buffer function in deposition hole and evaluation of buffer performance. These processes need to be understood in order to define the essential design parameters that affect these processes. Therefore material research (MARE project) is essential requirement for successful design development. Modelling (MODE project) provides support for all other projects. It requires significant resources, comprehensive understanding of different modelling methods and approaches, intense supervision and coordination. The significant issues are issues, which have been identified by the BENTO programme group to be possibly significant for performance of the buffer. The significant issues that need to be resolved at present are as follows: 1. Buffer cementation; 2. Buffer mineral alteration; 3. Erosion of buffer; 4. Piping of inflows through the buffer; 5. Insufficient swelling pressure of the buffer in dry drift sections, effect on rock spalling; 6. Post-glacial erosion (loss of buffer from exposure to glacial melt waters); 7. Cement-bentonite interaction; 8. Iron-bentonite interaction; 9. Freezing and Thawing of buffer. (authors)

  6. Key issues regarding digital libraries evaluation and integration

    CERN Document Server

    Shen, Rao; Fox, Edward A

    2013-01-01

    This is the second book based on the 5S (Societies, Scenarios, Spaces, Structures, Streams) approach to digital libraries (DLs). Leveraging the first volume, on Theoretical Foundations, we focus on the key issues of evaluation and integration. These cross-cutting issues serve as a bridge for those interested in DLs, connecting the introduction and formal discussion in the first book, with the coverage of key technologies in the third book, and of illustrative applications in the fourth book. These two topics have central importance in the DL field, allowing it to be treated scientifically as well as practically. In the scholarly world, we only really understand something if we know how to measure and evaluate it. In the Internet era of distributed information systems, we only can be practical at scale if we integrate across both systems and their associated content. Evaluation of DLs must take place atmultiple levels,so we can address the different entities and their associated measures. Thus, for digital obj...

  7. Workplace wellness programs in Canada: an exploration of key issues.

    Science.gov (United States)

    Morrison, Erin; MacKinnon, Neil J

    2008-01-01

    Faced with the reality of rising health costs, Canadian employers are thinking beyond traditional notions of responsibility for employee health and have begun to embrace Workplace Wellness Programs (WWPs). This article investigates the critical issues of WWPs in the Canadian context from the perspective of key stakeholders. Using a combination of literature and key informant interviews, seven key themes are presented along with recommendations for wider implementation of WWPs in Canada.

  8. U.S. Army War College Key Strategic Issues List

    National Research Council Canada - National Science Library

    2008-01-01

    The Key Strategic Issues List (KSIL) offers military and civilian researchers a ready reference of topics that are of particular interest to the Department of the Army and the Department of Defense...

  9. Trade Unions as Organisations: Key Issues and Problems of Internal ...

    African Journals Online (AJOL)

    The paper critically examines and evaluates inter alia Trade Unions as. Organisations and the key issues and problems of Internal Democracy within them. It transcends this analysis to assert that these core issues apply equally well to Political Organisations. Thus, from an ideological standpoint, Trade Unions play a great ...

  10. Village Health Volunteers: Key Issues Facing Agencies in Malawi

    African Journals Online (AJOL)

    the key issues facing health care providers in ... gral part of community-based health programmes ... health care services more accessible to everyone s. , .... health; villagers are often more willing to help meet the costs of services they value. 2.

  11. High-level radioactive waste disposal: Key geochemical issues and information needs for site characterization

    International Nuclear Information System (INIS)

    Brooks, D.J.; Bembia, P.J.; Bradbury, J.W.; Jackson, K.C.; Kelly, W.R.; Kovach, L.A.; Mo, T.; Tesoriero, J.A.

    1986-01-01

    Geochemistry plays a key role in determining the potential of a high-level radioactive waste disposal site for long-term radionuclide containment and isolation. The Nuclear Regulatory Commission (NRC) has developed a set of issues and information needs important for characterizing geochemistry at the potential sites being investigated by the Department of Energy Basalt Waste Isolation Project, Nevada Nuclear Waste Storage Investigations project, and Salt Repository Project. The NRC site issues and information needs consider (1) the geochemical environment of the repository, (2) changes to the initial geochemical environment caused by construction and waste emplacement, and (3) interactions that affect the transport of waste radionuclides to the accessible environment. The development of these issues and information needs supports the ongoing effort of the NRC to identify and address areas of geochemical data uncertainty during prelicensing interactions

  12. Risk and Performance Technologies: Identifying the Keys to Successful Implementation

    International Nuclear Information System (INIS)

    McClain, Lynn; Smith, Art; O'Regan, Patrick

    2002-01-01

    The nuclear power industry has been utilizing risk and performance based technologies for over thirty years. Applications of these technologies have included risk assessment (e.g. Individual Plant Examinations), burden reduction (e.g. Risk-Informed Inservice Inspection, RI-ISI) and risk management (Maintenance Rule, 10CFR50.65). Over the last five to ten years the number of risk-informed (RI) burden reduction initiatives has increased. Unfortunately, the efficiencies of some of these applications have been questionable. This paper investigates those attributes necessary to support successful, cost-effective RI-applications. The premise to this paper is that by understanding the key attributes that support one successful application, insights can be gleaned that will streamline/coordinate future RI-applications. This paper is an extension to a paper presented at the Pressure Vessel and Piping (PVP-2001) Conference. In that paper, a number issues and opportunities were identified that needed to be assessed in order to support future (and efficient) RI-applications. It was noted in the paper that a proper understanding and resolution of these issues will facilitate implementation of risk and performance technology in the operation, maintenance and design disciplines. In addition, it will provide the foundation necessary to support regulatory review and approval. (authors)

  13. Global energy outlook. Key issue paper no. 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The objectives of this key issue paper are to outline the expected trends in energy and electricity demand and supply that will impact the future of nuclear power and to highlight new realities that are likely to affect the assessment and implementation of alternative reactor and fuel cycle strategies in the next five to six decades. 14 refs, figs, tabs.

  14. Power quality event classification: an overview and key issues ...

    African Journals Online (AJOL)

    ... used for PQ events' classifications. Various artificial intelligent techniques which are used in PQ event classification are also discussed. Major Key issues and challenges in classifying PQ events are critically examined and outlined. Keywords: Power quality, PQ event classifiers, artificial intelligence techniques, PQ noise, ...

  15. Authenticated Blind Issuing of Symmetric Keys for Mobile Access Control System without Trusted Parties

    Directory of Open Access Journals (Sweden)

    Shin-Yan Chiou

    2013-01-01

    Full Text Available Mobile authentication can be used to verify a mobile user’s identity. Normally this is accomplished through the use of logon passwords, but this can raise the secret-key agreement problem between entities. This issue can be resolved by using a public-key cryptosystem, but mobile devices have limited computation ability and battery capacity and a PKI is needed. In this paper, we propose an efficient, non-PKI, authenticated, and blind issued symmetric key protocol for mobile access control systems. An easy-to-deploy authentication and authenticated key agreement system is designed such that empowered mobile devices can directly authorize other mobile devices to exchange keys with the server upon authentication using a non-PKI system without trusted parties. Empowered mobile users do not know the key value of the other mobile devices, preventing users from impersonating other individuals. Also, for security considerations, this system can revoke specific keys or keys issued by a specific user. The scheme is secure, efficient, and feasible and can be implemented in existing environments.

  16. Key Issues in Global Technological Innovation Projects

    Directory of Open Access Journals (Sweden)

    Roberto Sbragia

    2012-04-01

    Full Text Available This article aimed to identify those issues that were present in global technological innovation projects carried out by Brazilian multinational companies and which performance criterions these undertakings met. We investigated 36 global technological innovation projects from Brazilian multinational enterprises through a web-survey. Findings show that these companies went beyond the traditional iron triangle to evaluate their technological efforts and considered additional performance dimensions such as customer satisfaction, business results, and preparation for the future. Results also show high degree of presence for issues emerging from the industry, moderate degree of presence for issues emerging from both the project and R&D activities, and low degree of presence for issues emerging from the headquarters, the subsidiaries, and the external environment. Further research is needed to find out if and how these issues influenced the performance of the global technological innovation projects studied.DOI:10.5585/gep.v3i1.72

  17. Key Issues and Research Agendas in Lone Wolf Terrorism

    NARCIS (Netherlands)

    Spaaij, R.; Hamm, M.S.

    2015-01-01

    This article builds on recent contributions to the academic literature on lone wolf terrorism to critically examine key issues that are germane to the current state of play in this field of study. It finds that, overall, the recent academic literature still suffers from considerable problems

  18. Village health volunteers: key issues facing agencies in Malawi ...

    African Journals Online (AJOL)

    The participants discussed recruitment, training, rewards, retention, and roles of village health volunteers. This paper presents background data on village health volunteers in Malawi and elsewhere and reviews the key issues facing health care providers in working with village health volunteers. A copy of the workshop ...

  19. Enhancing regulatory effectiveness by improving the process for identifying and resolving generic issues

    International Nuclear Information System (INIS)

    Vander Molen, Harold J.

    2001-01-01

    The Generic Issues Program first began formally in response to a Commission directive in October of 1976. In 1983, it became one of the first programs to make successful use of probabilistic risk information to aid in regulatory decision-making. In the 16 years since the program became quantitative, 836 issues have been processed. Of these, 106 reactor safety issues were prioritized as requiring further evaluation to determine the final resolution. Approximately a dozen generic issues remain unresolved. Although there is far less reactor licensing activity than in the 1970s, new issues continue to be identified from research and operational experience. These issues often involve complex and controversial questions of safety and regulation, and an efficient and effective means of addressing these issues is essential for regulatory effectiveness. Issues that involve a significant safety question require swift, effective, enforceable, and cost-effective regulatory actions. Issues that are of little safety significance must be quickly shown to be so and dismissed in an expeditious manner so as to avoid unnecessary expenditure of limited resources and to reduce regulatory uncertainty. Additionally, in the time since the generic issue program began, probabilistic risk assessment techniques have advanced significantly while agency resources have continued to diminish. Accordingly, the paper discusses the steps that have been taken to enhance the effectiveness and efficiency of the generic issue resolution process. Additionally, four resolved issues are discussed, along with key elements of a proposed new procedure for resolving potential generic issues

  20. Using Eight Key Questions as an Inquiry-Based Framework for Ethical Reasoning Issues in a General Education Earth Systems and Climate Change Course

    Science.gov (United States)

    Johnson, E. A.; Ball, T. C.

    2014-12-01

    An important objective in general education geoscience courses is to help students evaluate social and ethical issues based upon scientific knowledge. It can be difficult for instructors trained in the physical sciences to design effective ways of including ethical issues in large lecture courses where whole-class discussions are not practical. The Quality Enhancement Plan for James Madison University, "The Madison Collaborative: Ethical Reasoning in Action," (http://www.jmu.edu/mc/index.shtml) has identified eight key questions to be used as a framework for developing ethical reasoning exercises and evaluating student learning. These eight questions are represented by the acronym FOR CLEAR and are represented by the concepts of Fairness, Outcomes, Responsibilities, Character, Liberty, Empathy, Authority, and Rights. In this study, we use the eight key questions as an inquiry-based framework for addressing ethical issues in a 100-student general education Earth systems and climate change course. Ethical reasoning exercises are presented throughout the course and range from questions of personal behavior to issues regarding potential future generations and global natural resources. In the first few exercises, key questions are identified for the students and calibrated responses are provided as examples. By the end of the semester, students are expected to identify key questions themselves and justify their own ethical and scientific reasoning. Evaluation rubrics are customized to this scaffolding approach to the exercises. Student feedback and course data will be presented to encourage discussion of this and other approaches to explicitly incorporating ethical reasoning in general education geoscience courses.

  1. Teacher-Student Sexual Relations: Key Risks and Ethical Issues

    Science.gov (United States)

    Sikes, Pat

    2010-01-01

    Researching actual or purported sexual contact between teachers and students raises many difficult ethical issues, questions and dilemmas, which may help to explain why few have ventured into the field. This experientially based paper addresses key problem areas under the headings of: the ethics of researching a sensitive taboo topic; the ethics…

  2. Key considerations and safety issues for the stretch power uprate at Chinshan Nuclear Power Station

    Energy Technology Data Exchange (ETDEWEB)

    Huang, P., E-mail: u808966@taipower.com.tw [Taiwan Power Company, Taipei, Taiwan (China)

    2014-07-01

    The Taiwan Power Company (TPC) has elected in recent years to implement the power uprate program as a key measure to improve the performance for TPC's nuclear power plants. The Measurement Uncertainty Recapture (MUR) power uprate for the TPC's three operating plants (reported in 16th PBNC) had been successfully implemented by July 2009. For the stretch power uprate (SPU) followed, the magnitude of uprate (~3%) is determined based on the available margins for original plant design, constant pressure approach (BWR) is adopted to simplify the evaluation, and major plant modifications are not considered. As the first application, the SPU safety analysis report (SAR) for the Chinshan plant was submitted to the ROCAEC in December 2010. A review task force was organized by the ROCAEC to perform a very thorough review. As the licensing bases are fully re-examined during the review process, many important issues have been identified and addressed. The key issues resolved include: conformance of SAR to ROCAEC's review guidance; re-examination of post-Fukushima comprehensive safety assessment; qualification of containment protective coatings; GL 96-06 (Assurance of Equipment Operability and Containment Integrity During DBA Conditions); credit for Containment Accident Pressure; issue for Annulus Pressurization Loads Evaluation. These issues required very extensive efforts to resolve. With the cooperative efforts by TPC and contractor (Institute of Nuclear Energy Research), however, all the issues were fully clarified and SAR was approved by ROCAEC on November 15, 2012. The first step SPU (2% OLTP) was successfully implemented in November 2012 at both units. (author)

  3. Future fuel cycle and reactor strategies. Key issue paper no. 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The scope of this paper includes those issues that are expected to remain or become important in the time period from 2015 to 2050. Events in this time frame are difficult to predict with any certainty, so the framework of this paper is necessarily somewhat speculative. The paper includes consideration of all facets of nuclear energy utilization, from ore extraction to final disposal of waste products. The paper first addresses the factors influencing the choice of reactor and fuel cycle. It then goes on to address the quantitatively largest category of reactor types expected to be important during the period; that is, thermal reactors burning uranium and plutonium fuel in various forms. The fast reactor type is then discussed both as stand-alone technology and as technology used in combination with thermal reactors. Thorium fuel use is discussed briefly. This paper is concentrated on the ``medium variant`` energy growth scenario identified in Key Issue Paper No. 1. The effects of either higher or lower growth could, of course, profoundly change the future development of the nuclear power industry. 31 refs, 5 figs, 4 tabs.

  4. Post discharge issues identified by a call-back program: identifying improvement opportunities.

    Science.gov (United States)

    Ojeda, Patricia I; Kara, Areeba

    2017-12-01

    The period following discharge from the hospital is one of heightened vulnerability. Discharge instructions serve as a guide during this transition. Yet, clinicians receive little feedback on the quality of this document that ties into the patients' experience. We reviewed the issues voiced by discharged patients via a call-back program and compared them to the discharge instructions they had received. At our institution, patients receive an automated call forty-eight hours following discharge inquiring about progress. If indicated by the response to the call, they are directed to a nurse who assists with problem solving. We reviewed the nursing documentation of these encounters for a period of nine months. The issues voiced were grouped into five categories: communication, medications, durable medical equipment/therapies, follow up and new or ongoing symptoms. The discharge instructions given to each patient were reviewed. We retrieved data on the number of discharges from each specialty from the hospital over the same period. A total of 592 patients voiced 685 issues. The numbers of patients discharged from medical or surgical services identified as having issues via the call-back line paralleled the proportions discharged from medical and surgical services from the hospital during the same period. Nearly a quarter of the issues discussed had been addressed in the discharge instructions. The most common category of issues was related to communication deficits including missing or incomplete information which made it difficult for the patient to enact or understand the plan of care. Medication prescription related issues were the next most common. Resource barriers and questions surrounding medications were often unaddressed. Post discharge issues affect patients discharged from all services equally. Data from call back programs may provide actionable targets for improvement, identify the inpatient team's 'blind spots' and be used to provide feedback to clinicians.

  5. Revisiting Employee Assistance Programs and Substance Use Problems in the Workplace: Key Issues and a Research Agenda

    OpenAIRE

    Levy Merrick, Elizabeth S.; Volpe-Vartanian, Joanna; Horgan, Constance M.; McCann, Bernard

    2007-01-01

    This column describes employee assistance program (EAPs) and identifies key issues for contemporary EAPs. These programs began as occupational alcohol programs and have evolved into more comprehensive resources. To better understand contemporary EAPs, the authors suggest a research agenda at includes descriptive studies to provide an up-to-date picture of services; investigations of how contemporary EAPs address substance use problems, including management consultation for early identificatio...

  6. NCAP projection displays: key issues for commercialization

    Science.gov (United States)

    Tomita, Akira; Jones, Philip J.

    1992-06-01

    Recently there has been much interest in a new polymer nematic dispersion technology, often called as NCAP, PDLC, PNLC, LCPC, etc., since projection displays using this technology have been shown to produce much brighter display images than projectors using conventional twisted nematic (TN) lightvalves. For commercializing projection displays based on this polymer nematic dispersion technology, the new materials must not only meet various electro- optic requirements, e.g., operational voltage, `off-state'' scattering angle, voltage holding ratio and hysteresis, but must also be stable over the lifetime of the product. This paper reports recent progress in the development of NCAP based projection displays and discusses some of the key commercialization issues.

  7. Ocean energy: key legal issues and challenges

    International Nuclear Information System (INIS)

    Wright, Glen; Rochette, Julien; O'Hagan, Anne Marie; De Groot, Jiska; Leroy, Yannick; Soininen, Niko; Salcido, Rachael; Castelos, Montserrat Abad; Jude, Simon; Kerr, Sandy

    2015-01-01

    Ocean energy is a novel renewable energy resource being developed as part of the push towards a 'Blue Economy'. The literature on ocean energy has focused on technical, environmental, and, increasingly, social and political aspects. Legal and regulatory factors have received less attention, despite their importance in supporting this new technology and ensuring its sustainable development. In this Issue Brief, we set out some key legal challenges for the development of ocean energy technologies, structured around the following core themes of marine governance: (i) international law; (ii) environmental impacts; (iii) rights and ownership; (iv) consenting processes; and (v) management of marine space and resources. (authors)

  8. Labont? Identifies Key Issues for Health Promoters in the New World Order

    OpenAIRE

    Raphael, Dennis

    2016-01-01

    For over 35 years Ronald Labonté has been critically analyzing the state of health promotion in Canada and the world. In 1981, he identified the shortcomings of the groundbreaking Lalonde Report by warning of the seductive appeal of so-called lifestyle approaches to health. Since then, he has left a trail of critical work identifying the barriers to — and opportunities for —health promotion work. More recently, he has shown how the rise of economic globalization and acceptance of neo-liberal ...

  9. Social Work Practice with Latinos: Key Issues for Social Workers

    Science.gov (United States)

    Furman, Rich; Negi, Nalini Junko; Iwamoto, Derek Kenji; Rowan, Diana; Shukraft, Allison; Gragg, Jennifer

    2009-01-01

    The Latino population is the fastest growing group in the United States; thus, it is imperative that social workers and other mental health practitioners be knowledgeable about the current literature on how to effectively serve this population. This article elucidates key issues and knowledge, such as immigration and migration concerns; discusses…

  10. Mixed Methods Research: What Are the Key Issues to Consider?

    Science.gov (United States)

    Ghosh, Rajashi

    2016-01-01

    Mixed methods research (MMR) is increasingly becoming a popular methodological approach in several fields due to the promise it holds for comprehensive understanding of complex problems being researched. However, researchers interested in MMR often lack reference to a guide that can explain the key issues pertaining to the paradigm wars…

  11. The use of conversation mapping to frame key perceptual issues facing the general dental practice system in England.

    Science.gov (United States)

    Harris, R V; Dancer, J M; Smith, D; Campbell, S

    2009-06-01

    To demonstrate the use of a novel qualitative methodology namely conversation mapping, which can be used to capture differences in stakeholder perspectives and give a root definition of the problem in a complex policy area. The methodology is used in the context of the changes introduced in the English general dental practice system in April 2006, to investigate the key issues facing the system, as perceived by general dental practitioners (GDPs). From a broad trigger statement, three transformational statements were produced. Each participant recorded their contribution on a hard diagrammatic form as a 'map', with others responding with their own written comment, thus generating three conversation maps. Thematic analysis resulted in the generation of a preliminary model summarising key perceptual issues. The five emergent themes identified were: financing, dentists' wants/needs, the role of the public and patients, system goals and policy level decision making. Financing was identified as the core category to which all other categories were related. Conversation mapping, a methodology arising from a systems approach, can be used to develop a 'rich picture' of an oral health care system in order to define the core problem within this policy area. Findings suggest that GDPs identify the financing of the system as a fundamental source of problems within the general dental practice system. This appears to be at variance with the perception of policy makers, who report a more limited view, identifying the system of remuneration as the 'heart of the problem'.

  12. Research Note Identifying key grazing indicators to monitor trends in ...

    African Journals Online (AJOL)

    Research Note Identifying key grazing indicators to monitor trends in the veld condition of Lambert's Bay Strandveld, South Africa. ... from which a minimum number of species necessary to monitor trends in the condition of the veld were determined, making it user-friendly for land-users, extension officers and others. The key ...

  13. Key issues in human resource planning for home support workers in Canada.

    Science.gov (United States)

    Keefe, Janice M; Knight, Lucy; Martin-Matthews, Anne; Légaré, Jacques

    2011-01-01

    This paper is a synthesis of research on recruitment and retention challenges for home support workers (HSWs) in Canada. Home support workers (HSWs) provide needed support with personal care and daily activities to older persons living in the community. Literature (peer reviewed, government, and non-government documents) published in the past decade was collected from systematic data base searches between January and September 2009, and yielded over 100 references relevant to home care human resources for older Canadians. Four key human resource issues affecting HSWs were identified: compensation, education and training, quality assurance, and working conditions. To increase the workforce and retain skilled employees, employers can tailor their marketing strategies to specific groups, make improvements in work environment, and learn about what workers value and what attracts them to home support work. Understanding these HR issues for HSWs will improve recruitment and retention strategies for this workforce by helping agencies to target their limited resources. Given the projected increase in demand for these workers, preparations need to begin now and consider long-term strategies involving multiple policy areas, such as health and social care, employment, education, and immigration.

  14. Highlights from panel discussion on key issues for future developments in microwave processing

    International Nuclear Information System (INIS)

    Gac, F.D.; Iskander, M.F.

    1992-01-01

    This paper reports on highlights from a panel discussion on Key Issues for Future Development in Microwave Processing. Although the panelists represented a mix of individuals from government, academia, and industry, only one aspect of industry was represented, namely microwave system manufacturers. For further panel discussions, it is recommended that the materials manufacturing (i.e., microwave user) sector also be represented. Three important points emerged from the panel discussion. The first deals with the credibility and usability of information, be it dielectric property measurements, experimental procedures, or microwave processing results. Second, a considerable communication and education gap continues to exist between the materials community and microwave engineers. Finally, a more realistic approach should be taken in identifying where microwave processing makes sense

  15. Issues in Moderation of National Curriculum Assessment at Key Stage 3.

    Science.gov (United States)

    Cowling, Les

    1994-01-01

    Highlights the issues of moderation of teacher judgments for accountability and moderation for achieving consistent assessments. Discusses the meaning of moderation, the need for moderating teacher judgments, approaches to moderation, methods of moderation, and most appropriate methods of moderation at Key Stage 3. Presents an approach to…

  16. Nanoscale ferroelectrics and multiferroics key processes and characterization issues, and nanoscale effects

    CERN Document Server

    Alguero, Miguel

    2016-01-01

    This book reviews the key issues in processing and characterization of nanoscale ferroelectrics and multiferroics, and provides a comprehensive description of their properties, with an emphasis in differentiating size effects of extrinsic ones like boundary or interface effects. Recently described nanoscale novel phenomena are also addressed. Organized into three parts it addresses key issues in processing (nanostructuring), characterization (of the nanostructured materials) and nanoscale effects. Taking full advantage of the synergies between nanoscale ferroelectrics and multiferroics, it covers materials nanostructured at all levels, from ceramic technologies like ferroelectric nanopowders, bulk nanostructured ceramics and thick films, and magnetoelectric nanocomposites, to thin films, either polycrystalline layer heterostructures or epitaxial systems, and to nanoscale free standing objects with specific geometries, such as nanowires and tubes at different levels of development. The book is developed from t...

  17. European key issues concerning natural gas: Dependence and vulnerability

    International Nuclear Information System (INIS)

    Reymond, Mathias

    2007-01-01

    Due to the high demand for natural gas from emerging countries and because natural gas has become an increasingly valuable resource is electricity production, natural gas demand should increase. This paper re-examines the geopolitical key issues related to natural gas as well as the uneven distribution of natural gas resources on a worldwide scale. This paper proposes to define the significance of liquefied natural gas in gas exchanges and it analyses the problem of European gas vulnerability using several indicators

  18. Key issues and technical route of cyber physical distribution system

    Science.gov (United States)

    Zheng, P. X.; Chen, B.; Zheng, L. J.; Zhang, G. L.; Fan, Y. L.; Pei, T.

    2017-01-01

    Relying on the National High Technology Research and Development Program, this paper introduced the key issues in Cyber Physical Distribution System (CPDS), mainly includes: composite modelling method and interaction mechanism, system planning method, security defence technology, distributed control theory. Then on this basis, the corresponding technical route is proposed, and a more detailed research framework along with main schemes to be adopted is also presented.

  19. Human Health Effects of Trichloroethylene: Key Findings and Scientific Issues

    Science.gov (United States)

    Jinot, Jennifer; Scott, Cheryl Siegel; Makris, Susan L.; Cooper, Glinda S.; Dzubow, Rebecca C.; Bale, Ambuja S.; Evans, Marina V.; Guyton, Kathryn Z.; Keshava, Nagalakshmi; Lipscomb, John C.; Barone, Stanley; Fox, John F.; Gwinn, Maureen R.; Schaum, John; Caldwell, Jane C.

    2012-01-01

    Background: In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) completed a toxicological review of trichloroethylene (TCE) in September 2011, which was the result of an effort spanning > 20 years. Objectives: We summarized the key findings and scientific issues regarding the human health effects of TCE in the U.S. EPA’s toxicological review. Methods: In this assessment we synthesized and characterized thousands of epidemiologic, experimental animal, and mechanistic studies, and addressed several key scientific issues through modeling of TCE toxicokinetics, meta-analyses of epidemiologic studies, and analyses of mechanistic data. Discussion: Toxicokinetic modeling aided in characterizing the toxicological role of the complex metabolism and multiple metabolites of TCE. Meta-analyses of the epidemiologic data strongly supported the conclusions that TCE causes kidney cancer in humans and that TCE may also cause liver cancer and non-Hodgkin lymphoma. Mechanistic analyses support a key role for mutagenicity in TCE-induced kidney carcinogenicity. Recent evidence from studies in both humans and experimental animals point to the involvement of TCE exposure in autoimmune disease and hypersensitivity. Recent avian and in vitro mechanistic studies provided biological plausibility that TCE plays a role in developmental cardiac toxicity, the subject of substantial debate due to mixed results from epidemiologic and rodent studies. Conclusions: TCE is carcinogenic to humans by all routes of exposure and poses a potential human health hazard for noncancer toxicity to the central nervous system, kidney, liver, immune system, male reproductive system, and the developing embryo/fetus. PMID:23249866

  20. The emerging role of Big Data in key development issues: Opportunities, challenges, and concerns

    Directory of Open Access Journals (Sweden)

    Nir Kshetri

    2014-12-01

    Full Text Available This paper presents a review of academic literature, policy documents from government organizations and international agencies, and reports from industries and popular media on the trends in Big Data utilization in key development issues and its worthwhileness, usefulness, and relevance. By looking at Big Data deployment in a number of key economic sectors, it seeks to provide a better understanding of the opportunities and challenges of using it for addressing key issues facing the developing world. It reviews the uses of Big Data in agriculture and farming activities in developing countries to assess the capabilities required at various levels to benefit from Big Data. It also provides insights into how the current digital divide is associated with and facilitated by the pattern of Big Data diffusion and its effective use in key development areas. It also discusses the lessons that developing countries can learn from the utilization of Big Data in big corporations as well as in other activities in industrialized countries.

  1. Key issues of the common French-German safety approach for future PWRs

    International Nuclear Information System (INIS)

    Frisch, W.; Rohde, J.; Gros, G.; Queniart, D.

    1996-01-01

    The general common safety approach issued in May 1993 contains safety objectives, general principles and already some technical principles. Based on general safety approach, detailed recommendations have been developed in 1994 on key issues such as: system design and use of PSA; integrity of the primary circuit; external hazards; severe accidents and containment design; radiological consequences of reference accidents and low pressure core melt accidents. A selection of the detailed recommendations is presented in the full paper. (author)

  2. Training: Who Needs It? Research Report 1995. Key Issues for Providers.

    Science.gov (United States)

    Hotel and Catering Training Co., London (England).

    Aimed at all those involved in the supply of training and vocational education for the hospitality industry, this report summarizes findings of the research report, "Training Who Needs It?" It draws out and explores in more detail key issues relating to the provision of training, support, and related initiatives for the industry. Section…

  3. Climate Watchlist: Key issues for Cancun negotiations

    Energy Technology Data Exchange (ETDEWEB)

    Chandani, Achala; Siegele, Linda

    2010-11-15

    We must mitigate and adapt to climate change. On this, the international community is agreed. But exactly how to do that is still up for debate. There were high hopes that last year's UN climate talks in Copenhagen would deliver a legally binding agreement for action on climate change. But the outcome — the Copenhagen Accord — was instead a political 'statement of intent' that fell significantly short of expectations. Now, after a year of interim meetings and several negotiating texts, parties to the UN Framework Convention on Climate Change (UNFCCC) are gathering in Cancun, Mexico, to try again. Their success will largely depend on settling disputes — particularly between the developed and developing world — about six key issues: shared vision; adaptation; climate finance; technology transfer; reducing emissions from deforestation and degradation; and post-2012 emissions reduction targets.

  4. Key regulatory and safety issues emerging NEA activities. Lessons Learned from Fukushima Dai-ichi NPS Accident - Key Regulatory and Safety Issues

    International Nuclear Information System (INIS)

    Nakoski, John

    2013-01-01

    A presentation was provided on the key safety and regulatory issues and an update of activities undertaken by the NEA and its members in response to the accident at the Fukushima Daiichi nuclear power stations (NPS) on 11 March 2011. An overview of the accident sequence and the consequences was provided that identified the safety functions that were lost (electrical power, core cooling, and primary containment) that lead to units 1, 2, and 3 being in severe accident conditions with large off-site releases. Key areas identified for which activities of the NEA and member countries are in progress include accident management; defence-in-depth; crisis communication; initiating events; operating experience; deterministic and probabilistic assessments; regulatory infrastructure; radiological protection and public health; and decontamination and recovery. For each of these areas, a brief description of the on-going and planned NEA activities was provided within the three standing technical committees of the NEA with safety and regulatory mandates (the Committee on Nuclear Regulatory Activities - CNRA, the Committee on the Safety of Nuclear Installations - CSNI, and the Committee on Radiation Protection and Public Health - CRPPH). On-going activities of CNRA include a review of enhancement being made to the regulatory aspects for the oversight of on-site accident management strategies and processes in light of the lessons learned from the accident; providing guidance to regulators on crisis communication; and supporting the peer review of the safety assessments of risk-significant research reactor facilities in light of the accident. Within the scope of the CSNI mandate, activities are being undertaken to better understand accident progression; characteristics of new fuel designs; and a benchmarking study of fast-running software for estimating source term under severe accident conditions to support protective measure recommendations. CSNI also has ongoing work in human

  5. New Doctoral Graduates in the Knowledge Economy: Trends and Key Issues

    Science.gov (United States)

    Pedersen, Heidi Skovgaard

    2014-01-01

    This paper examines the key issues at stake for national economies in increasing the number of PhDs to meet expected needs for human capital in science, technology and innovation using illustrations mainly from the European Commission's "Careers of Doctorate Holders" surveys on PhD labour market outcomes; it has been shown that PhD…

  6. Tamper-proof secret image-sharing scheme for identifying cheated secret keys and shared images

    Science.gov (United States)

    Chen, Chien-Chang; Liu, Chong-An

    2013-01-01

    A (t,n) secret image-sharing scheme shares a secret image to n participants, and the t users recover the image. During the recovery procedure of a conventional secret image-sharing scheme, cheaters may use counterfeit secret keys or modified shared images to cheat other users' secret keys and shared images. A cheated secret key or shared image leads to an incorrect secret image. Unfortunately, the cheater cannot be identified. We present an exponent and modulus-based scheme to provide a tamper-proof secret image-sharing scheme for identifying cheaters on secret keys or shared images. The proposed scheme allows users to securely select their secret key. This assignment can be performed over networks. Modulus results of each shared image is calculated to recognize cheaters of a shared image. Experimental results indicate that the proposed scheme is excellent at identifying cheated secret keys and shared images.

  7. Methods of Developing User-Friendly Keys to Identify Green Sea Turtles (Chelonia mydas L. from Photographs

    Directory of Open Access Journals (Sweden)

    Jane R. Lloyd

    2012-01-01

    Full Text Available Identifying individual animals is important in understanding their ecology and behaviour, as well as providing estimates of population sizes for conservation efforts. We produce identification keys from photographs of green sea turtles to identify them while foraging in Akumal Bay, Mexico. We create three keys, which (a minimise the length of the key, (b present the most obvious differential characteristics first, and (c remove the strict dichotomy from key b. Keys were capable of identifying >99% of turtles in >2500 photographs during the six-month study period. The keys differed significantly in success rate for students to identify individual turtles, with key (c being the best with >70% success and correctly being followed further than other keys before making a mistake. User-friendly keys are, therefore, a suitable method for the photographic identification of turtles and could be used for other large marine vertebrates in conservation or behavioural studies.

  8. Managing and developing key supplier relationships : An introduction to the special issue, discussion and implications

    NARCIS (Netherlands)

    Ivens, B.; van de Vijver, M.A.R.; Vos, G.C.J.M.

    2013-01-01

    This article provides an introduction to this special issue on managing and developing key supplier relationships. Key suppliers are increasingly seen as strategic assets of buying companies which need careful nurturing to fully utilize their potential for value creation. The six articles of this

  9. Several key issues on using 137Cs method for soil erosion estimation

    Science.gov (United States)

    This work was to examine several key issues of using the cesium-137 method to estimate soil erosion rates in order to improve and standardize the method. Based on the comprehensive review and synthesis of a large body of published literature and the author’s extensive research experience, several k...

  10. Identifying Key Issues and Potential Solutions for Integrated Arrival, Departure, Surface Operations by Surveying Stakeholder Preferences

    Science.gov (United States)

    Aponso, Bimal; Coppenbarger, Richard A.; Jung, Yoon; Quon, Leighton; Lohr, Gary; O’Connor, Neil; Engelland, Shawn

    2015-01-01

    NASA's Aeronautics Research Mission Directorate (ARMD) collaborates with the FAA and industry to provide concepts and technologies that enhance the transition to the next-generation air-traffic management system (NextGen). To facilitate this collaboration, ARMD has a series of Airspace Technology Demonstration (ATD) sub-projects that develop, demonstrate, and transitions NASA technologies and concepts for implementation in the National Airspace System (NAS). The second of these sub-projects, ATD-2, is focused on the potential benefits to NAS stakeholders of integrated arrival, departure, surface (IADS) operations. To determine the project objectives and assess the benefits of a potential solution, NASA surveyed NAS stakeholders to understand the existing issues in arrival, departure, and surface operations, and the perceived benefits of better integrating these operations. NASA surveyed a broad cross-section of stakeholders representing the airlines, airports, air-navigation service providers, and industry providers of NAS tools. The survey indicated that improving the predictability of flight times (schedules) could improve efficiency in arrival, departure, and surface operations. Stakeholders also mentioned the need for better strategic and tactical information on traffic constraints as well as better information sharing and a coupled collaborative planning process that allows stakeholders to coordinate IADS operations. To assess the impact of a potential solution, NASA sketched an initial departure scheduling concept and assessed its viability by surveying a select group of stakeholders for a second time. The objective of the departure scheduler was to enable flights to move continuously from gate to cruise with minimal interruption in a busy metroplex airspace environment using strategic and tactical scheduling enhanced by collaborative planning between airlines and service providers. The stakeholders agreed that this departure concept could improve schedule

  11. BENCHMARKING - PRACTICAL TOOLS IDENTIFY KEY SUCCESS FACTORS

    Directory of Open Access Journals (Sweden)

    Olga Ju. Malinina

    2016-01-01

    Full Text Available The article gives a practical example of the application of benchmarking techniques. The object of study selected fashion store Company «HLB & M Hennes & Mauritz», located in the shopping center «Gallery», Krasnodar. Hennes & Mauritz. The purpose of this article is to identify the best ways to develop a fashionable brand clothing store Hennes & Mauritz on the basis of benchmarking techniques. On the basis of conducted market research is a comparative analysis of the data from different perspectives. The result of the author’s study is a generalization of the ndings, the development of the key success factors that will allow to plan a successful trading activities in the future, based on the best experience of competitors.

  12. Identifying Key Attributes for Protein Beverages.

    Science.gov (United States)

    Oltman, A E; Lopetcharat, K; Bastian, E; Drake, M A

    2015-06-01

    This study identified key attributes of protein beverages and evaluated effects of priming on liking of protein beverages. An adaptive choice-based conjoint study was conducted along with Kano analysis to gain insight on protein beverage consumers (n = 432). Attributes evaluated included label claim, protein type, amount of protein, carbohydrates, sweeteners, and metabolic benefits. Utility scores for levels and importance scores for attributes were determined. Subsequently, two pairs of clear acidic whey protein beverages were manufactured that differed by age of protein source or the amount of whey protein per serving. Beverages were evaluated by 151 consumers on two occasions with or without priming statements. One priming statement declared "great flavor," the other priming statement declared 20 g protein per serving. A two way analysis of variance was applied to discern the role of each priming statement. The most important attribute for protein beverages was sweetener type, followed by amount of protein, followed by type of protein followed by label claim. Beverages with whey protein, naturally sweetened, reduced sugar and ≥15 g protein per serving were most desired. Three consumer clusters were identified, differentiated by their preferences for protein type, sweetener and amount of protein. Priming statements positively impacted concept liking (P 0.05). Consistent with trained panel profiles of increased cardboard flavor with higher protein content, consumers liked beverages with 10 g protein more than beverages with 20 g protein (6.8 compared with 5.7, P appeal. © 2015 Institute of Food Technologists®

  13. A User Centered Innovation Approach Identifying Key User Values for the E-Newspaper

    OpenAIRE

    Carina Ihlström Eriksson; Jesper Svensson

    2009-01-01

    We have studied the pre-adoption phase of the e-newspaper, i.e. a newspaper published with e-paper technology. The research question of this article is: In what way can a user centered innovation process contribute to identifying key values in mobile innovations? The aim of this article is threefold: firstly, to identify key values for the e-newspaper, secondly, to examine the intention to adopt a new possible innovation and thirdly, to explore user centered design processes ability to captur...

  14. Revisiting Employee Assistance Programs and Substance Use Problems in the Workplace: Key Issues and a Research Agenda

    Science.gov (United States)

    Levy Merrick, Elizabeth S.; Volpe-Vartanian, Joanna; Horgan, Constance M.; McCann, Bernard

    2012-01-01

    This column describes employee assistance program (EAPs) and identifies key issues for contemporary EAPs. These programs began as occupational alcohol programs and have evolved into more comprehensive resources. To better understand contemporary EAPs, the authors suggest a research agenda at includes descriptive studies to provide an up-to-date picture of services; investigations of how contemporary EAPs address substance use problems, including management consultation for early identification; further study of EAPs’ effects on outcomes, such as productivity and work group outcomes; examination of the relationship between EAPs and other workplace resources; further examination of influences on EAP utilization; and development and testing of EAP performance measures. PMID:17914000

  15. Key Regulatory Issues for Digital Instrumentation and Control Systems at Nuclear Power Plants

    International Nuclear Information System (INIS)

    Korsah, Kofi; Wood, Richard Thomas

    2008-01-01

    To help reduce the uncertainty associated with application of digital instrumentation and controls (I and C) technology in nuclear power plants, the Nuclear Regulatory Commission (NRC) has issued six Interim Staff Guidance (ISG) documents that address the current regulatory positions on what are considered the significant digital I and C issues. These six documents address the following topics: Cyber Security, Diversity and Defense-in-Depth, Risk Informed Digital I and C Regulation, Communication issues, Human Factors and the Digital I and C Licensing Process (currently issued as Draft). After allowing for further refinement based on additional technical insight gathered by NRC staff through near-term research and detailed review of relevant experience, it is expected that updated positions ultimately will be incorporated into regulatory guides and staff review procedures. This paper presents an overview of the guidance provided by the NRC-issued ISGs on key technology considerations (i.e., the first five documents above) for safety-related digital I and C systems.

  16. International symposium on nuclear fuel cycle and reactor strategy: Adjusting to new realities. Key issue papers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The key issue papers review the following issues: global energy outlook; present status and environmental implications of the different fuel cycles; future fuel cycle and reactor strategies; safety, health and environmental implications of the different fuel cycles; non-proliferation and safeguards aspects; international cooperation. Refs, figs, tabs.

  17. International symposium on nuclear fuel cycle and reactor strategy: Adjusting to new realities. Key issue papers

    International Nuclear Information System (INIS)

    1997-06-01

    The key issue papers review the following issues: global energy outlook; present status and environmental implications of the different fuel cycles; future fuel cycle and reactor strategies; safety, health and environmental implications of the different fuel cycles; non-proliferation and safeguards aspects; international cooperation. Refs, figs, tabs

  18. Key issues and challenges in developing a pedagogical intervention in the simulation skills center--an action research study.

    Science.gov (United States)

    Reierson, Inger Åse; Hvidsten, Anne; Wighus, Marianne; Brungot, Solvor; Bjørk, Ida Torunn

    2013-07-01

    Simulation skills centers (SSC) are considered important learning arenas for preparing and qualifying nursing students. Limited clinical placements and claims of diminished learning opportunities raise concerns that newly educated nurses lack proficiency in many psychomotor skills. Accordingly, there is an increased focus on learning in the SSC. However, it has been questioned if the pedagogical underpinning of teaching and learning in the SSC is missing or unclear. At a bachelor nursing education in Norway, there was a desire to change practice and enhance learning in the SSC by systematic use of The Model of Practical Skill Performance (Bjørk and Kirkevold, 2000). A participatory action research design was chosen. A pedagogical intervention was developed and implemented in 2010 in a cohort of eighty-seven first year bachelor nursing students during their basic nursing skill course. The intervention is shortly described. This article reports key issues and challenges that emerged during development of the new intervention. Data to inform the study were collected via thorough meeting minutes and the project leader's logbook, and analyzed using fieldnotes analysis. Six key issues and challenges were identified. These are presented and discussed consecutively in light of their importance for development and implementation of the new intervention. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Identifying veterinary students' capacity for moral behavior concerning animal ethics issues.

    Science.gov (United States)

    Verrinder, Joy M; Phillips, Clive J C

    2014-01-01

    Veterinarians face unique animal ethics challenges as practitioners and policy advisors to government and industry. Changing societal attitudes, cultural diversity, and the often conflicting needs and interests of patients and clients contribute to moral distress. Yet little has been done to identify veterinarians' capacity to address these animal ethics issues. In this study, first-year and final-year veterinary students in an Australian university were surveyed to explore moral sensitivity, moral motivation, and moral character and their relationship with moral reasoning. The majority of students were concerned about animal ethics issues and had experienced moral distress in relation to the treatment of animals. Most believed that veterinarians should address the wider social issues of animal protection and that veterinary medicine should require a commitment to animals' interests over owners'/caregivers' interests. There was less agreement that the veterinary profession was sufficiently involved in addressing animal ethics issues. The principal motivators for studying veterinary medicine were, in declining importance, enjoyment in working with animals, helping sick and injured animals, and improving the way animals are treated. However, most students had taken little or no action to address animal ethics issues. These results suggest that both first- and fifth-year veterinary students are sensitive to animal ethics issues and are motivated to prioritize the interests of animals but have little experience in taking action to address these issues. Further research is needed to determine ways to identify and assess these moral behavior components in veterinary education to develop veterinarians' capacity to address animal ethics issues.

  20. Identifying the key concerns of Irish persons with intellectual disability.

    Science.gov (United States)

    García Iriarte, Edurne; O'Brien, Patricia; McConkey, Roy; Wolfe, Marie; O'Doherty, Siobhain

    2014-11-01

    Internationally, people with intellectual disability are socially marginalized, and their rights under the United Nations Convention for the Rights of Persons with Disabilities (CRPD) are often ignored. This paper aims to define the key concerns of adults with an intellectual disability in relation to their participation in society using an inclusive research strategy for both data gathering and data analysis. A national study involving 23 focus groups and 168 persons was conducted on the island of Ireland with people with intellectual disability as co-facilitators. A thematic content analysis was undertaken of the verbatim transcripts initially by university co-researchers, and 19 themes were identified. Co-researchers with intellectual disability joined in identifying the eight core themes. These were as follows: living options, employment, relationships, citizenship, leisure time, money management, self-advocacy, and communication. The concerns are discussed within the framework of the CRPD, and implications for transforming service policy are drawn. Why we did the research In many countries, people with intellectual disability have difficulties doing things other people without disabilities do, for example to study, to get a job or to live independently. They also find that their rights are not respected under the Convention on the Rights of Persons with Disabilities (the Convention). We did this study to Learn what are the main issues for adults with intellectual disability in Ireland. Do research with people with intellectual disability. How we did the research People with intellectual disability and their supporters worked with university researchers to plan and do the research. We met with people in groups and 168 people told us about things important to them. What we found out We found that there were very important things that people talked about in the groups. We chose the most important: living options, employment, relationships, rights, leisure, money

  1. Beaufort Sea oil spills state of knowledge review and identification of key issues

    International Nuclear Information System (INIS)

    Dickins, David; Devenis, Peter; Buist, Ian; Belore, Randy; Trudel, K.; Potter, S.

    2011-01-01

    The Arctic holds the world's largest remaining untapped gas reserves and some of its largest undeveloped oil reserves. A significant proportion of these reserves lie offshore, in the Arctic's shallow and biologically productive shelf seas. This paper describes the results of a recently-completed study commissioned by the environmental studies research funds to document the current state of knowledge with regard to counter-measures for oil spills that might result from exploration and production activities in the Canadian Beaufort Sea. It provides a brief overview of the main advances in the past 20 years and the state-of-the-art for each of the main categories of counter-measures. An additional goal of the study was to identify key issues of concern regarding planning and response to spills in the Beaufort, to provide a current reference document for use by industry, regulators and the public, and prepare a geographic database of coastal resources, vulnerabilities and sensitivities that may influence the choice of oil spill containment and recovery methods.

  2. The diffusion of renewable energy technology: an analytical framework and key issues for research

    International Nuclear Information System (INIS)

    Jacobsson, S.; Johnson, A.

    2000-01-01

    During the last two decades there has been a great deal of research on renewable energy technologies. It is commonly thought that very little has come out of this research in terms of commercially interesting technologies. The first objective of this paper is to demonstrate that this perception is no longer correct; in the 1990s there has been a double-digit growth rate in the market for some renewable energy technologies. The consequent alteration in the energy system, is, however, a slow, painful and highly uncertain process. This process, we argue, needs to be studied using an innovation system perspective where the focus is on networks, institutions and firms' perceptions, competencies and strategies. The second objective of the paper is therefore to present the bare bones of such an analytical framework. A third objective is to identify a set of key issues related to the speed and direction of that transformation process which needs to be studied further. (author)

  3. Social Network Analysis Identifies Key Participants in Conservation Development.

    Science.gov (United States)

    Farr, Cooper M; Reed, Sarah E; Pejchar, Liba

    2018-05-01

    Understanding patterns of participation in private lands conservation, which is often implemented voluntarily by individual citizens and private organizations, could improve its effectiveness at combating biodiversity loss. We used social network analysis (SNA) to examine participation in conservation development (CD), a private land conservation strategy that clusters houses in a small portion of a property while preserving the remaining land as protected open space. Using data from public records for six counties in Colorado, USA, we compared CD participation patterns among counties and identified actors that most often work with others to implement CDs. We found that social network characteristics differed among counties. The network density, or proportion of connections in the network, varied from fewer than 2 to nearly 15%, and was higher in counties with smaller populations and fewer CDs. Centralization, or the degree to which connections are held disproportionately by a few key actors, was not correlated strongly with any county characteristics. Network characteristics were not correlated with the prevalence of wildlife-friendly design features in CDs. The most highly connected actors were biological and geological consultants, surveyors, and engineers. Our work demonstrates a new application of SNA to land-use planning, in which CD network patterns are examined and key actors are identified. For better conservation outcomes of CD, we recommend using network patterns to guide strategies for outreach and information dissemination, and engaging with highly connected actor types to encourage widespread adoption of best practices for CD design and stewardship.

  4. Key technological issues in LMFBR high-temperature structural design - the US perspective

    International Nuclear Information System (INIS)

    Corum, J.M.

    1984-01-01

    The purpose of this paper is: (1) to review the key technological issues in LMFBR high-temperature structural design, particularly as they relate to cost reduction; and (2) to provide an overview of activities sponsored by the US Department of Energy to resolve the issues and to establish stable, standardized, and defensible structural design methods and criteria. Specific areas of discussion include: weldments, structural validation tests, simplified design analysis procedures, design procedures for piping, validation of the methodology for notch-like geometries, improved life assessment procedures, thermal striping, extension of the methodology to new materials, and ASME high-temperature Code reform needs. The perceived problems and needs in each area are discussed, and the current status of related US activities is given

  5. eHealth in Wound Care,- overview and key issues to consider before implementation

    DEFF Research Database (Denmark)

    Moore, Zena; Angel, Donna; Bjerregaard, Julie

    2015-01-01

    Purpose This document aims to provide wound care clinicians with a rapid and structured overview of the key issues related to use of eHealth applications (telemedicine and telehealth) within wound care. This includes: • An overview of terminology and available literature • Guidance on the methodo......Purpose This document aims to provide wound care clinicians with a rapid and structured overview of the key issues related to use of eHealth applications (telemedicine and telehealth) within wound care. This includes: • An overview of terminology and available literature • Guidance...... on the methodology for evaluation of eHealth solutions • An introduction to and discussion of the potential benefits of eHealth technologies in wound care, and the possible barriers to their implementation • Recommendations for ensuring a good implementation process and supporting involvement of wound care...... professionals in safeguarding that eHealth solutions meet the needs of the patients. Methodology The document sections lean on the structure and focus areas of the Model for ASsessment of Telemedicine (MAST) which defines crucial items to evaluate an eHealth application. The content of the document is developed...

  6. The sustainable use of tropical coastal resources - A key conservation issue

    Energy Technology Data Exchange (ETDEWEB)

    Holdgate, M W [IUCN-World Conservation Union, Gland (Switzerland)

    1993-01-01

    The three papers covered in this review form a series, addressing broadly the same issues in increasing detail. The paper by Carl Gustaf Lundin and Olof Linden, on 'Coastal ecosystems: Attempts to manage a threatened resource', takes a wide view of the coastal zones (the regions between the seaward margins of the continental shelves, in water depths of around 200 m and the landward edge of the coastal plains at a comparable altitude above mean sea level), and the nature of the pressures upon them. The paper by Magnus A.K. Ngoile and Chris J. Horrill, on 'Coastal ecosystems productivity and ecosystem protection: Coastal ecosystem management', focuses very much on these same issues of use and pressure in the Eastern Africa Region. The paper by M.C.Oehman, A. Rajasuriya and O. Linden, on 'Human disturbances on coral reefs in Sri Lanka: A case study' looks in some depth at the situation on three selected reef systems in the one country. All the papers address the key question of how the management of coastal resources should change, in order to avoid continuing degradation and the cost and impoverishment it is likely to bring. The three papers mentioned is published in this issue of Ambio, p. 461-480

  7. The Key Issues of Labor Migration in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Marie JELINKOVA

    2007-04-01

    Full Text Available This paper aims to highlight some often occurring failures that need to be eliminated when attempting to develop an integral and efficient policy on labor migration. As an example, a brief overview of the development of immigration policies and its critical shortcomings in the Czech Republic is provided. Following this, the paper analyzes two aspects: the protection of migrant workers and the trafficking in human beings. In particular, the paper deals with three crucial issues of labor migration which are: (1 the inconsistent aims of immigration policies, (2 the client system, and (3 the dependence on middlemen. The paper also focuses on the role of state, police, and NGO’s in the trafficking in human beings and forced labor or labor exploitation in the Czech Republic. In addition, the legislation on forced labor and the possibilities of assistance to trafficked person are analyzed.By comparing various aspects of immigration policy, this paper covers some, but certainly not all, of the key issues concerning the process of immigrant integration. Several suggestions are made that could improve the situation of labor migrants in a significant way.

  8. Non-equilibrium physics and evolution—adaptation, extinction, and ecology: a Key Issues review

    International Nuclear Information System (INIS)

    Kussell, E; Vucelja, M

    2014-01-01

    Evolutionary dynamics in nature constitute an immensely complex non-equilibrium process. We review the application of physical models of evolution, by focusing on adaptation, extinction, and ecology. In each case, we examine key concepts by working through examples. Adaptation is discussed in the context of bacterial evolution, with a view toward the relationship between growth rates, mutation rates, selection strength, and environmental changes. Extinction dynamics for an isolated population are reviewed, with emphasis on the relation between timescales of extinction, population size, and temporally correlated noise. Ecological models are discussed by focusing on the effect of spatial interspecies interactions on diversity. Connections between physical processes—such as diffusion, turbulence, and localization—and evolutionary phenomena are highlighted. (key issues reviews)

  9. Understanding Price Elasticities to Inform Public Health Research and Intervention Studies: Key Issues

    Science.gov (United States)

    Nghiem, Nhung; Genç, Murat; Blakely, Tony

    2013-01-01

    Pricing policies such as taxes and subsidies are important tools in preventing and controlling a range of threats to public health. This is particularly so in tobacco and alcohol control efforts and efforts to change dietary patterns and physical activity levels as a means of addressing increases in noncommunicable diseases. To understand the potential impact of pricing policies, it is critical to understand the nature of price elasticities for consumer products. For example, price elasticities are key parameters in models of any food tax or subsidy that aims to quantify health impacts and cost-effectiveness. We detail relevant terms and discuss key issues surrounding price elasticities to inform public health research and intervention studies. PMID:24028228

  10. Understanding price elasticities to inform public health research and intervention studies: key issues.

    Science.gov (United States)

    Nghiem, Nhung; Wilson, Nick; Genç, Murat; Blakely, Tony

    2013-11-01

    Pricing policies such as taxes and subsidies are important tools in preventing and controlling a range of threats to public health. This is particularly so in tobacco and alcohol control efforts and efforts to change dietary patterns and physical activity levels as a means of addressing increases in noncommunicable diseases. To understand the potential impact of pricing policies, it is critical to understand the nature of price elasticities for consumer products. For example, price elasticities are key parameters in models of any food tax or subsidy that aims to quantify health impacts and cost-effectiveness. We detail relevant terms and discuss key issues surrounding price elasticities to inform public health research and intervention studies.

  11. Topic A. Have all the relevant issues been identified

    International Nuclear Information System (INIS)

    Bernero, R.M.

    1994-01-01

    This work is an answer to the question : have all the relevant issues been identified? The author tries to answer more particularly to the following three points : 1) can risk or responsibility for action be imposed on future generations. 2) Are current safety norms suitable for the future? 3) what controls are appropriate for inter generational cost/benefit evaluations. (O.L.)

  12. Nickel exposure from keys: a Brazilian issue.

    Science.gov (United States)

    Suzuki, Nathalie Mie; Duarte, Ida Alzira Gomes; Hafner, Mariana de Figueiredo Silva; Lazzarini, Rosana

    2017-01-01

    Keys are a significant source of exposure to metal allergens and can be a relevant problem for nickel-allergic individuals. This study aimed to perform nickel and cobalt spot testing among the 5 most common Brazilian brands of keys. Among the tested keys, 100% showed positive result to nickel spot test, 83,3% presented strong positive reaction. 50% exhibited cobalt release as well. Nickel release from keys is very common in our country and may cause a negative impact on sensitized individual's quality of life. Study's results highlight the importance of establishing directives to regulate nickel release in Brazil.

  13. Neuropathological biomarker candidates in brain tumors: key issues for translational efficiency.

    Science.gov (United States)

    Hainfellner, J A; Heinzl, H

    2010-01-01

    Brain tumors comprise a large spectrum of rare malignancies in children and adults that are often associated with severe neurological symptoms and fatal outcome. Neuropathological tumor typing provides both prognostic and predictive tissue information which is the basis for optimal postoperative patient management and therapy. Molecular biomarkers may extend and refine prognostic and predictive information in a brain tumor case, providing more individualized and optimized treatment options. In the recent past a few neuropathological brain tumor biomarkers have translated smoothly into clinical use whereas many candidates show protracted translation. We investigated the causes of protracted translation of candidate brain tumor biomarkers. Considering the research environment from personal, social and systemic perspectives we identified eight determinants of translational success: methodology, funding, statistics, organization, phases of research, cooperation, self-reflection, and scientific progeny. Smoothly translating biomarkers are associated with low degrees of translational complexity whereas biomarkers with protracted translation are associated with high degrees. Key issues for translational efficiency of neuropathological brain tumor biomarker research seem to be related to (i) the strict orientation to the mission of medical research, that is the improval of medical practice as primordial purpose of research, (ii) definition of research priorities according to clinical needs, and (iii) absorption of translational complexities by means of operatively beneficial standards. To this end, concrete actions should comprise adequate scientific education of young investigators, and shaping of integrative diagnostics and therapy research both on the local level and the level of influential international brain tumor research platforms.

  14. The key physics and technology issues in the intense-beam proton accelerators

    International Nuclear Information System (INIS)

    Fu Shinian; Fang Shouxian

    2002-01-01

    Beam power is required to raise one order in the next generation spallation neutron source. There are still some physics and technology difficulties need to be overcome, even though no fatal obstacle exists due to the rapid development of the technology in intense-beam accelerator in recent years. Therefore, it is highly demanded to clarify the key issues and to lunch an R and D program to break through the technological barriers before author start to build the expansive machine. The new technological challenge arises from the high beam current, the high accelerator power and the high demand on the reliability and stability of the accelerator operation. The author will discuss these issues and the means to resolve them, as well as the state of the art in a few of major technological disciplines. Finally, the choice the framework of intense-beam accelerator is discussed

  15. Sexuality in old age: key issues, gender differences and future proposals

    Directory of Open Access Journals (Sweden)

    Noelia Fernández-Rouco

    2013-12-01

    Full Text Available This work presents a brief overview of some of the most important issues related to sexuality during old age. First, it presents the state of the current situation, in order to later explore some of the elements that have been considered key factors in experiencing sexuality, specifically in this stage of life, while exploring certain needs and difficulties. Similarly, some of the differences between men and women, within this context, are presented. Finally, future proposals aimed at better understanding this topic in old age are presented, with suggestions on how to improve wellbeing and care in regard to sexuality among the aging population.

  16. Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies (Final Report)

    Science.gov (United States)

    EPA announced the availability of the final report, Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies. This report summarizes some of the recent progress in characterizing uncertainty and variability in physi...

  17. Nuclear fuel cycle and reactor strategies: Adjusting to new realities. Key issue papers

    International Nuclear Information System (INIS)

    1997-01-01

    The international symposium ''Nuclear Fuel Cycle and Reactor Strategy: Adjusting to new Realities'' was organized to face the new realities in the nuclear fuel cycle and to consider options on how these new realities could be addressed. The Key Issue Papers treat the various subjects from both short and long term perspectives. In so doing, they address the likely development of all aspects concerning the nuclear fuel cycle up to the year 2050

  18. Issues in identifying germ tube positive yeasts by conventional methods.

    Science.gov (United States)

    Yazdanpanah, Atta; Khaithir, Tzar Mohd Nizam

    2014-01-01

    Candida speciation is vital for epidemiology and management of candidiasis. Nonmolecular conventional methods often fail to identify closely related germ tube positive yeasts from clinical specimens. The present study was conducted to identify these yeasts and to highlight issues in conventional versus molecular methods of identification. A total of 98 germ tube positive yeasts from high vaginal swabs were studied over a 12-month period. Isolates were examined with various methods including growth at 42 °C and 45 °C on Sabouraud dextrose agar (SDA), color development on CHROMagar Candida medium, chlamydospore production on corn meal agar at 25 °C, carbohydrate assimilation using ID 32C system, and polymerase chain reaction using a single pair of primers targeting the hyphal wall protein 1 (Hwp1) gene. Of all the isolates studied, 97 were molecularly confirmed as C. albicans and one isolate was identified as C. dubliniensis. No C. africana was detected in this study. The molecular method used in our study was an accurate and useful tool for discriminating C. albicans, C. dubliniensis, and C. africana. The conventional methods, however, were less accurate and riddled with many issues that will be discussed in further details. © 2013 Wiley Periodicals, Inc.

  19. Integrated systems approach identifies risk regulatory pathways and key regulators in coronary artery disease.

    Science.gov (United States)

    Zhang, Yan; Liu, Dianming; Wang, Lihong; Wang, Shuyuan; Yu, Xuexin; Dai, Enyu; Liu, Xinyi; Luo, Shanshun; Jiang, Wei

    2015-12-01

    Coronary artery disease (CAD) is the most common type of heart disease. However, the molecular mechanisms of CAD remain elusive. Regulatory pathways are known to play crucial roles in many pathogenic processes. Thus, inferring risk regulatory pathways is an important step toward elucidating the mechanisms underlying CAD. With advances in high-throughput data, we developed an integrated systems approach to identify CAD risk regulatory pathways and key regulators. Firstly, a CAD-related core subnetwork was identified from a curated transcription factor (TF) and microRNA (miRNA) regulatory network based on a random walk algorithm. Secondly, candidate risk regulatory pathways were extracted from the subnetwork by applying a breadth-first search (BFS) algorithm. Then, risk regulatory pathways were prioritized based on multiple CAD-associated data sources. Finally, we also proposed a new measure to prioritize upstream regulators. We inferred that phosphatase and tensin homolog (PTEN) may be a key regulator in the dysregulation of risk regulatory pathways. This study takes a closer step than the identification of disease subnetworks or modules. From the risk regulatory pathways, we could understand the flow of regulatory information in the initiation and progression of the disease. Our approach helps to uncover its potential etiology. We developed an integrated systems approach to identify risk regulatory pathways. We proposed a new measure to prioritize the key regulators in CAD. PTEN may be a key regulator in dysregulation of the risk regulatory pathways.

  20. Key Issues in Modeling of Complex 3D Structures from Video Sequences

    Directory of Open Access Journals (Sweden)

    Shengyong Chen

    2012-01-01

    Full Text Available Construction of three-dimensional structures from video sequences has wide applications for intelligent video analysis. This paper summarizes the key issues of the theory and surveys the recent advances in the state of the art. Reconstruction of a scene object from video sequences often takes the basic principle of structure from motion with an uncalibrated camera. This paper lists the typical strategies and summarizes the typical solutions or algorithms for modeling of complex three-dimensional structures. Open difficult problems are also suggested for further study.

  1. Performance Issues Along the Six Elements of Holcim Solusi Rumah's Marketing Mix and Solution Recommedations

    OpenAIRE

    Susana, Apriliani Dewi; Titus, Amol

    2013-01-01

    This study aims at identifying key issues in SR franchise business along the six elements of marketing mix: people, partner, place, product, promotion, and price, and then propose solution recommendations for the identified issues. Data is collected through a method of in-depth interviews with key SR stakeholders, internally and externally, namely end customers, SR personnels, and SR franchisees. Issues identified are mapped into a Problem Tree Analysis diagram to determine causal relations...

  2. Alcohol & drug abuse: Revisiting employee assistance programs and substance use problems in the workplace: key issues and a research agenda.

    Science.gov (United States)

    Merrick, Elizabeth S Levy; Volpe-Vartanian, Joanna; Horgan, Constance M; McCann, Bernard

    2007-10-01

    This column describes employee assistance program (EAPs) and identifies key issues for contemporary EAPs. These programs began as occupational alcohol programs and have evolved into more comprehensive resources. To better understand contemporary EAPs, the authors suggest a research agenda that includes descriptive studies to provide an up-to-date picture of services; investigations of how contemporary EAPs address substance use problems, including management consultation for early identification; further study of EAPs' effects on outcomes, such as productivity and work group outcomes; examination of the relationship between EAPs and other workplace resources; further examination of influences on EAP utilization; and development and testing of EAP performance measures.

  3. Identifying key genes associated with acute myocardial infarction.

    Science.gov (United States)

    Cheng, Ming; An, Shoukuan; Li, Junquan

    2017-10-01

    This study aimed to identify key genes associated with acute myocardial infarction (AMI) by reanalyzing microarray data. Three gene expression profile datasets GSE66360, GSE34198, and GSE48060 were downloaded from GEO database. After data preprocessing, genes without heterogeneity across different platforms were subjected to differential expression analysis between the AMI group and the control group using metaDE package. P FI) network. Then, DEGs in each module were subjected to pathway enrichment analysis using DAVID. MiRNAs and transcription factors predicted to regulate target DEGs were identified. Quantitative real-time polymerase chain reaction (RT-PCR) was applied to verify the expression of genes. A total of 913 upregulated genes and 1060 downregulated genes were identified in the AMI group. A FI network consists of 21 modules and DEGs in 12 modules were significantly enriched in pathways. The transcription factor-miRNA-gene network contains 2 transcription factors FOXO3 and MYBL2, and 2 miRNAs hsa-miR-21-5p and hsa-miR-30c-5p. RT-PCR validations showed that expression levels of FOXO3 and MYBL2 were significantly increased in AMI, and expression levels of hsa-miR-21-5p and hsa-miR-30c-5p were obviously decreased in AMI. A total of 41 DEGs, such as SOCS3, VAPA, and COL5A2, are speculated to have roles in the pathogenesis of AMI; 2 transcription factors FOXO3 and MYBL2, and 2 miRNAs hsa-miR-21-5p and hsa-miR-30c-5p may be involved in the regulation of the expression of these DEGs.

  4. Impacts on non-human biota from a generic geological disposal facility for radioactive waste: some key assessment issues.

    Science.gov (United States)

    Robinson, C A; Smith, K L; Norris, S

    2010-06-01

    This paper provides an overview of key issues associated with the application of currently available biota dose assessment methods to consideration of potential environmental impacts from geological disposal facilities. It explores philosophical, methodological and practical assessment issues and reviews the implications of test assessment results in the context of recent and on-going challenges and debates.

  5. Impacts on non-human biota from a generic geological disposal facility for radioactive waste: some key assessment issues

    International Nuclear Information System (INIS)

    Robinson, C A; Smith, K L; Norris, S

    2010-01-01

    This paper provides an overview of key issues associated with the application of currently available biota dose assessment methods to consideration of potential environmental impacts from geological disposal facilities. It explores philosophical, methodological and practical assessment issues and reviews the implications of test assessment results in the context of recent and on-going challenges and debates.

  6. Ethical issues in research involving children and young people

    International Nuclear Information System (INIS)

    Scally, Andy

    2014-01-01

    This article identifies the key ethical issues that need to be addressed in any research study involving children and young people, accessed through the NHS. It makes specific reference to the Declaration of Helsinki and to additional guidance developed for researchers from a variety of disciplines, both within healthcare and in other fields of study. The focus of the paper is on defining the key ethical issues, identifying the complexities in the legislative framework underpinning research involving this patient group and offering practical advice on when, and how, ethical approval needs to be sought

  7. Identifying key performance indicators for nursing and midwifery care using a consensus approach.

    Science.gov (United States)

    McCance, Tanya; Telford, Lorna; Wilson, Julie; Macleod, Olive; Dowd, Audrey

    2012-04-01

    The aim of this study was to gain consensus on key performance indicators that are appropriate and relevant for nursing and midwifery practice in the current policy context. There is continuing demand to demonstrate effectiveness and efficiency in health and social care and to communicate this at boardroom level. Whilst there is substantial literature on the use of clinical indicators and nursing metrics, there is less evidence relating to indicators that reflect the patient experience. A consensus approach was used to identify relevant key performance indicators. A nominal group technique was used comprising two stages: a workshop involving all grades of nursing and midwifery staff in two HSC trusts in Northern Ireland (n = 50); followed by a regional Consensus Conference (n = 80). During the workshop, potential key performance indicators were identified. This was used as the basis for the Consensus Conference, which involved two rounds of consensus. Analysis was based on aggregated scores that were then ranked. Stage one identified 38 potential indicators and stage two prioritised the eight top-ranked indicators as a core set for nursing and midwifery. The relevance and appropriateness of these indicators were confirmed with nurses and midwives working in a range of settings and from the perspective of service users. The eight indicators identified do not conform to the majority of other nursing metrics generally reported in the literature. Furthermore, they are strategically aligned to work on the patient experience and are reflective of the fundamentals of nursing and midwifery practice, with the focus on person-centred care. Nurses and midwives have a significant contribution to make in determining the extent to which these indicators are achieved in practice. Furthermore, measurement of such indicators provides an opportunity to evidence of the unique impact of nursing/midwifery care on the patient experience. © 2011 Blackwell Publishing Ltd.

  8. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA. Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  9. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA.Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  10. Strengthening and redesigning flood risk governance in Europe: an overview of seven key issues and how they are being dealt with in six European countries

    Directory of Open Access Journals (Sweden)

    Hegger Dries

    2016-01-01

    Full Text Available European countries, especially urban areas, face increasing flood risks due to urbanization, increase of exposure and damage potential, and the effects of climate change. In literature and in practice, it is argued that a diversification of Flood Risk Management Strategies (FRMSs makes countries more flood resilient. The latter requires innovations in existing Flood Risk Governance Arrangements, development of new arrangements and the coordination of these arrangements, but it also requires these arrangements to be tailored to their physical and institutional context. Within the EU FP7 project STAR-FLOOD (2012-2016, a comparative analysis and evaluation of flood risk governance in Belgium, England, France, The Netherlands, Poland and Sweden has been conducted. The project identified at least seven key issues that are relevant for all researched countries (and probably also beyond. These key issues deal with the topics of (i diversifying Flood Risk Management Strategies (ii establishing connectivity between actors, levels and sectors through what we coin “bridging mechanisms” (iii achieving coproduction between public and private actors; (iv improving fragmented and often non-enforceable rule systems; (v optimising available resources for FRM; (vi operationalising the notion of “diversification of FRM strategies” in a country-specific way; (vii follow general design principles for improving FRM that are sufficiently tailored to local circumstances. Drawing on all project deliverables, this paper will briefly review each key issue, discuss salient similarities and differences between the countries and point at ways forward.

  11. eHealth Literacy and Health Behaviors Affecting Modern College Students: A Pilot Study of Issues Identified by the American College Health Association

    Science.gov (United States)

    Collins, William Bart; Wilson, Kari; Linnemeier, Georgiann; Englebert, Andrew Mark

    2017-01-01

    Background The eHealth Literacy Scale (eHEALS) has been widely adopted by researchers to understand how eHealth literacy can be put into context. eHealth researchers need to know how to promote positive health behavior changes across college students, given the importance of the Internet to acquire and use health information. The American College Health Association identified a set of key health issues that affect college students today. By understanding how eHEALS might be related to college students’ maintenance of their health and their use of online health resources, researchers will be provided with a better understanding of eHealth literacy and its pragmatic implications for health campaigns and future interventions. Objective The goal of the study was to examine what eHEALS reveals about college student health behaviors identified by the American College Health Association. To understand college student current health maintenance and their intentions to maintain their health and use online resources, the theory of planned behavior was used as the theoretical framework for the study. Methods Data were collected via a survey of 422 college students that included the eHEALS measure and questions about health issues based on the recommendations of the American College Health Association. These questions asked about college student current health, subsequent use of online health resources, and their intention to maintain their health and make use of such resources in the future. Results eHEALS was positively and significantly associated with all 8 areas of health issues identified by the American College Health Association for college student current maintenance of health and use of online health resources and for future intention of health maintenance and use of online resources. Key issues that emerged with eHealth literacy were maintaining safe sex practices and seeking out related information, seeking out information on an exercise regime, information on

  12. Summary of Key Issues Raised in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) Meeting.

    Science.gov (United States)

    Baumel, Amit; Baker, Justin; Birnbaum, Michael L; Christensen, Helen; De Choudhury, Munmun; Mohr, David C; Muench, Fred; Schlosser, Danielle; Titov, Nick; Kane, John M

    2018-05-01

    Technology provides an unparalleled opportunity to remove barriers to earlier identification and engagement in services for mental and addictive disorders by reaching people earlier in the course of illness and providing links to just-in-time, cost-effective interventions. Achieving this opportunity, however, requires stakeholders to challenge underlying assumptions about traditional pathways to mental health care. In this Open Forum, the authors highlight key issues discussed in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) meeting-held October 13-14, 2016, in New York City-that are related to three identified areas in which technology provides important and unique opportunities to advance early identification, increase service engagement, and decrease the duration of untreated mental and addictive disorders.

  13. Identifying Key Drivers of Return Reversal with Dynamical Bayesian Factor Graph.

    Directory of Open Access Journals (Sweden)

    Shuai Zhao

    Full Text Available In the stock market, return reversal occurs when investors sell overbought stocks and buy oversold stocks, reversing the stocks' price trends. In this paper, we develop a new method to identify key drivers of return reversal by incorporating a comprehensive set of factors derived from different economic theories into one unified dynamical Bayesian factor graph. We then use the model to depict factor relationships and their dynamics, from which we make some interesting discoveries about the mechanism behind return reversals. Through extensive experiments on the US stock market, we conclude that among the various factors, the liquidity factors consistently emerge as key drivers of return reversal, which is in support of the theory of liquidity effect. Specifically, we find that stocks with high turnover rates or high Amihud illiquidity measures have a greater probability of experiencing return reversals. Apart from the consistent drivers, we find other drivers of return reversal that generally change from year to year, and they serve as important characteristics for evaluating the trends of stock returns. Besides, we also identify some seldom discussed yet enlightening inter-factor relationships, one of which shows that stocks in Finance and Insurance industry are more likely to have high Amihud illiquidity measures in comparison with those in other industries. These conclusions are robust for return reversals under different thresholds.

  14. Identifying key hospital service quality factors in online health communities.

    Science.gov (United States)

    Jung, Yuchul; Hur, Cinyoung; Jung, Dain; Kim, Minki

    2015-04-07

    The volume of health-related user-created content, especially hospital-related questions and answers in online health communities, has rapidly increased. Patients and caregivers participate in online community activities to share their experiences, exchange information, and ask about recommended or discredited hospitals. However, there is little research on how to identify hospital service quality automatically from the online communities. In the past, in-depth analysis of hospitals has used random sampling surveys. However, such surveys are becoming impractical owing to the rapidly increasing volume of online data and the diverse analysis requirements of related stakeholders. As a solution for utilizing large-scale health-related information, we propose a novel approach to identify hospital service quality factors and overtime trends automatically from online health communities, especially hospital-related questions and answers. We defined social media-based key quality factors for hospitals. In addition, we developed text mining techniques to detect such factors that frequently occur in online health communities. After detecting these factors that represent qualitative aspects of hospitals, we applied a sentiment analysis to recognize the types of recommendations in messages posted within online health communities. Korea's two biggest online portals were used to test the effectiveness of detection of social media-based key quality factors for hospitals. To evaluate the proposed text mining techniques, we performed manual evaluations on the extraction and classification results, such as hospital name, service quality factors, and recommendation types using a random sample of messages (ie, 5.44% (9450/173,748) of the total messages). Service quality factor detection and hospital name extraction achieved average F1 scores of 91% and 78%, respectively. In terms of recommendation classification, performance (ie, precision) is 78% on average. Extraction and

  15. Telemedicine: licensing and other legal issues.

    Science.gov (United States)

    Siegal, Gil

    2011-12-01

    The growth of information technology and telecommunications has created promising opportunities for better, faster, more accessible, barrier-free health care; telemedicine (TM). The feasibility of many TM projects depends on resolving legal issues. Mastering technical issues or providing training remain important benchmarks for implementation of TM, but legal issues constrain progress. This article identifies the key legal issues, maps current legislation, and offers a forecast of necessary steps to expedite the dissemination of TM. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Thermal hydraulics of sodium-cooled fast reactors - key issues and highlights

    International Nuclear Information System (INIS)

    Ninokata, H.; Kamide, H.

    2011-01-01

    In this paper key issues and highlighted topics in thermal hydraulics are discussed in connection to the current Japan's sodium-cooled fast reactor development efforts. In particular, design study and related researches of the Japan Sodium-cooled Fast Reactor (JSFR) are focused. Several innovative technologies, e.g., compact reactor vessel, two-loop system, fully natural circulation decay heat removal, and recriticality free core, have been investigated in order to reduce construction cost and to achieve higher level of reactor safety. Preliminary evaluations of innovative technologies to be applied to JSFR are on-going. Here, progress of design study is introduced. Then, research and development activities on the thermal hydraulics related to the innovative technologies are briefly reviewed. (author)

  17. Using sensitivity analysis to identify key factors for the propagation of a plant epidemic.

    Science.gov (United States)

    Rimbaud, Loup; Bruchou, Claude; Dallot, Sylvie; Pleydell, David R J; Jacquot, Emmanuel; Soubeyrand, Samuel; Thébaud, Gaël

    2018-01-01

    Identifying the key factors underlying the spread of a disease is an essential but challenging prerequisite to design management strategies. To tackle this issue, we propose an approach based on sensitivity analyses of a spatiotemporal stochastic model simulating the spread of a plant epidemic. This work is motivated by the spread of sharka, caused by plum pox virus , in a real landscape. We first carried out a broad-range sensitivity analysis, ignoring any prior information on six epidemiological parameters, to assess their intrinsic influence on model behaviour. A second analysis benefited from the available knowledge on sharka epidemiology and was thus restricted to more realistic values. The broad-range analysis revealed that the mean duration of the latent period is the most influential parameter of the model, whereas the sharka-specific analysis uncovered the strong impact of the connectivity of the first infected orchard. In addition to demonstrating the interest of sensitivity analyses for a stochastic model, this study highlights the impact of variation ranges of target parameters on the outcome of a sensitivity analysis. With regard to sharka management, our results suggest that sharka surveillance may benefit from paying closer attention to highly connected patches whose infection could trigger serious epidemics.

  18. Obtaining subjects' consent to publish identifying personal information: current practices and identifying potential issues.

    Science.gov (United States)

    Yoshida, Akiko; Dowa, Yuri; Murakami, Hiromi; Kosugi, Shinji

    2013-11-25

    In studies publishing identifying personal information, obtaining consent is regarded as necessary, as it is impossible to ensure complete anonymity. However, current journal practices around specific points to consider when obtaining consent, the contents of consent forms and how consent forms are managed have not yet been fully examined. This study was conducted to identify potential issues surrounding consent to publish identifying personal information. Content analysis was carried out on instructions for authors and consent forms developed by academic journals in four fields (as classified by Journal Citation Reports): medicine general and internal, genetics and heredity, pediatrics, and psychiatry. An online questionnaire survey of editors working for journals that require the submission of consent forms was also conducted. Instructions for authors were reviewed for 491 academic journals (132 for medicine general and internal, 147 for genetics and heredity, 100 for pediatrics, and 112 for psychiatry). Approximately 40% (203: 74 for medicine general and internal, 31 for genetics and heredity, 58 for pediatrics, and 40 for psychiatry) stated that subject consent was necessary. The submission of consent forms was required by 30% (154) of the journals studied, and 10% (50) provided their own consent forms for authors to use. Two journals mentioned that the possible effects of publication on subjects should be considered. Many journal consent forms mentioned the difficulties in ensuring complete anonymity of subjects, but few addressed the study objective, the subjects' right to refuse consent and the withdrawal of consent. The main reason for requiring the submission of consent forms was to confirm that consent had been obtained. Approximately 40% of journals required subject consent to be obtained. However, differences were observed depending on the fields. Specific considerations were not always documented. There is a need to address issues around the study

  19. Obtaining subjects’ consent to publish identifying personal information: current practices and identifying potential issues

    Science.gov (United States)

    2013-01-01

    Background In studies publishing identifying personal information, obtaining consent is regarded as necessary, as it is impossible to ensure complete anonymity. However, current journal practices around specific points to consider when obtaining consent, the contents of consent forms and how consent forms are managed have not yet been fully examined. This study was conducted to identify potential issues surrounding consent to publish identifying personal information. Methods Content analysis was carried out on instructions for authors and consent forms developed by academic journals in four fields (as classified by Journal Citation Reports): medicine general and internal, genetics and heredity, pediatrics, and psychiatry. An online questionnaire survey of editors working for journals that require the submission of consent forms was also conducted. Results Instructions for authors were reviewed for 491 academic journals (132 for medicine general and internal, 147 for genetics and heredity, 100 for pediatrics, and 112 for psychiatry). Approximately 40% (203: 74 for medicine general and internal, 31 for genetics and heredity, 58 for pediatrics, and 40 for psychiatry) stated that subject consent was necessary. The submission of consent forms was required by 30% (154) of the journals studied, and 10% (50) provided their own consent forms for authors to use. Two journals mentioned that the possible effects of publication on subjects should be considered. Many journal consent forms mentioned the difficulties in ensuring complete anonymity of subjects, but few addressed the study objective, the subjects’ right to refuse consent and the withdrawal of consent. The main reason for requiring the submission of consent forms was to confirm that consent had been obtained. Conclusion Approximately 40% of journals required subject consent to be obtained. However, differences were observed depending on the fields. Specific considerations were not always documented. There is a need

  20. A matter of definition--key elements identified in a discourse analysis of definitions of palliative care.

    Science.gov (United States)

    Pastrana, T; Jünger, S; Ostgathe, C; Elsner, F; Radbruch, L

    2008-04-01

    For more than 30 years, the term "palliative care" has been used. From the outset, the term has undergone a series of transformations in its definitions and consequently in its tasks and goals. There remains a lack of consensus on a definition. The aim of this article is to analyse the definitions of palliative care in the specialist literature and to identify the key elements of palliative care using discourse analysis: a qualitative methodology. The literature search focused on definitions of the term 'palliative medicine' and 'palliative care' in the World Wide Web and medical reference books in English and German. A total of 37 English and 26 German definitions were identified and analysed. Our study confirmed the lack of a consistent meaning concerning the investigated terms, reflecting on-going discussion about the nature of the field among palliative care practitioners. Several common key elements were identified. Four main categories emerged from the discourse analysis of the definition of palliative care: target groups, structure, tasks and expertise. In addition, the theoretical principles and goals of palliative care were discussed and found to be key elements, with relief and prevention of suffering and improvement of quality of life as main goals. The identified key elements can contribute to the definition of the concept 'palliative care'. Our study confirms the importance of semantic and ethical influences on palliative care that should be considered in future research on semantics in different languages.

  1. KEY ISSUES OF CONCEPTS' FORMATION OF THE NETWORK OF RESOURCE CENTER OF DISTANCE EDUCATION OF GENERAL EDUCATION INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Yuriy M. Bogachkov

    2013-06-01

    Full Text Available In the article the problem of constructing a network of resource centers for Distance Education to meet the needs of general secondary schools is presented. Modern educational trends in the use of Internet services in education are viewed.  Main contradictions, solution of which helps to create a network of resource centers, are identified. The definition of key terms related to the range of issues are given. The basic categories of participants, who  implementation of e-learning and networking are oriented on. There are considered the basic tasks of  distance education resource centers' functioning and types of supporting: personnel, regulatory, informative, systematic and  technical etc. The review of possible models of implementation of  students' distance education is reviewed . Three options for business models of resource centers, depending on funding  sources are offered.

  2. Identifying Human Factors Issues in Aircraft Maintenance Operations

    Science.gov (United States)

    Veinott, Elizabeth S.; Kanki, Barbara G.; Shafto, Michael G. (Technical Monitor)

    1995-01-01

    Maintenance operations incidents submitted to the Aviation Safety Reporting System (ASRS) between 1986-1992 were systematically analyzed in order to identify issues relevant to human factors and crew coordination. This exploratory analysis involved 95 ASRS reports which represented a wide range of maintenance incidents. The reports were coded and analyzed according to the type of error (e.g, wrong part, procedural error, non-procedural error), contributing factors (e.g., individual, within-team, cross-team, procedure, tools), result of the error (e.g., aircraft damage or not) as well as the operational impact (e.g., aircraft flown to destination, air return, delay at gate). The main findings indicate that procedural errors were most common (48.4%) and that individual and team actions contributed to the errors in more than 50% of the cases. As for operational results, most errors were either corrected after landing at the destination (51.6%) or required the flight crew to stop enroute (29.5%). Interactions among these variables are also discussed. This analysis is a first step toward developing a taxonomy of crew coordination problems in maintenance. By understanding what variables are important and how they are interrelated, we may develop intervention strategies that are better tailored to the human factor issues involved.

  3. Doubly-Special Relativity: Facts, Myths and Some Key Open Issues

    Directory of Open Access Journals (Sweden)

    Giovanni Amelino-Camelia

    2010-03-01

    Full Text Available I report, emphasizing some key open issues and some aspects that are particularly relevant for phenomenology, on the status of the development of “doubly-special” relativistic (“DSR” theories with both an observer-independent high-velocity scale and an observer-independent small-length/large-momentum scale, possibly relevant for the Planck-scale/quantum-gravity realm. I also give a true/false characterization of the structure of these theories. In particular, I discuss a DSR scenario without modification of the energy-momentum dispersion relation and without the қ-Poincaré Hopf algebra, a scenario with deformed Poincaré symmetries which is not a DSR scenario, some scenarios with both an invariant length scale and an invariant velocity scale which are not DSR scenarios, and a DSR scenario in which it is easy to verify that some observable relativistic (but non-special-relativistic features are insensitive to possible nonlinear redefinitions of symmetry generators.

  4. Key technical issues associated with a method of pulse compression. Final technical report

    International Nuclear Information System (INIS)

    Hunter, R.O. Jr.

    1980-06-01

    Key technical issues for angular multiplexing as a method of pulse compression in a 100 KJ KrF laser have been studied. Environmental issues studied include seismic vibrations man-made vibrations, air propagation, turbulence, and thermal gradient-induced density fluctuations. These studies have been incorporated in the design of mirror mounts and an alignment system, both of which are reported. A design study and performance analysis of the final amplifier have been undertaken. The pulse compression optical train has been designed and assessed as to its performance. Individual components are described and analytical relationships between the optical component size, surface quality, damage threshold and final focus properties are derived. The optical train primary aberrations are obtained and a method for aberration minimization is presented. Cost algorithms for the mirrors, mounts, and electrical hardware are integrated into a cost model to determine system costs as a function of pulse length, aperture size, and spot size

  5. Key clinical features to identify girls with CDKL5 mutations.

    Science.gov (United States)

    Bahi-Buisson, Nadia; Nectoux, Juliette; Rosas-Vargas, Haydeé; Milh, Mathieu; Boddaert, Nathalie; Girard, Benoit; Cances, Claude; Ville, Dorothée; Afenjar, Alexandra; Rio, Marlène; Héron, Delphine; N'guyen Morel, Marie Ange; Arzimanoglou, Alexis; Philippe, Christophe; Jonveaux, Philippe; Chelly, Jamel; Bienvenu, Thierry

    2008-10-01

    Mutations in the human X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been shown to cause infantile spasms as well as Rett syndrome (RTT)-like phenotype. To date, less than 25 different mutations have been reported. So far, there are still little data on the key clinical diagnosis criteria and on the natural history of CDKL5-associated encephalopathy. We screened the entire coding region of CDKL5 for mutations in 183 females with encephalopathy with early seizures by denaturing high liquid performance chromatography and direct sequencing, and we identified in 20 unrelated girls, 18 different mutations including 7 novel mutations. These mutations were identified in eight patients with encephalopathy with RTT-like features, five with infantile spasms and seven with encephalopathy with refractory epilepsy. Early epilepsy with normal interictal EEG and severe hypotonia are the key clinical features in identifying patients likely to have CDKL5 mutations. Our study also indicates that these patients clearly exhibit some RTT features such as deceleration of head growth, stereotypies and hand apraxia and that these RTT features become more evident in older and ambulatory patients. However, some RTT signs are clearly absent such as the so called RTT disease profile (period of nearly normal development followed by regression with loss of acquired fine finger skill in early childhood and characteristic intensive eye communication) and the characteristic evolution of the RTT electroencephalogram. Interestingly, in addition to the overall stereotypical symptomatology (age of onset and evolution of the disease) resulting from CDKL5 mutations, atypical forms of CDKL5-related conditions have also been observed. Our data suggest that phenotypic heterogeneity does not correlate with the nature or the position of the mutations or with the pattern of X-chromosome inactivation, but most probably with the functional transcriptional and/or translational consequences of CDKL5

  6. Predictive model identifies key network regulators of cardiomyocyte mechano-signaling.

    Directory of Open Access Journals (Sweden)

    Philip M Tan

    2017-11-01

    Full Text Available Mechanical strain is a potent stimulus for growth and remodeling in cells. Although many pathways have been implicated in stretch-induced remodeling, the control structures by which signals from distinct mechano-sensors are integrated to modulate hypertrophy and gene expression in cardiomyocytes remain unclear. Here, we constructed and validated a predictive computational model of the cardiac mechano-signaling network in order to elucidate the mechanisms underlying signal integration. The model identifies calcium, actin, Ras, Raf1, PI3K, and JAK as key regulators of cardiac mechano-signaling and characterizes crosstalk logic imparting differential control of transcription by AT1R, integrins, and calcium channels. We find that while these regulators maintain mostly independent control over distinct groups of transcription factors, synergy between multiple pathways is necessary to activate all the transcription factors necessary for gene transcription and hypertrophy. We also identify a PKG-dependent mechanism by which valsartan/sacubitril, a combination drug recently approved for treating heart failure, inhibits stretch-induced hypertrophy, and predict further efficacious pairs of drug targets in the network through a network-wide combinatorial search.

  7. Strategic management and organizational behavior in dental education: reflections on key issues in an environment of change.

    Science.gov (United States)

    Dunning, David G; Durham, Timothy M; Lange, Brian M; Aksu, Mert N

    2009-06-01

    With issues such as shrinking revenue, access to care, faculty workloads, and graying faculty, dental schools are faced with difficult challenges that fall to dental school deans to manage. Do dental school deans have the organizational skill sets and ethical frameworks necessary to address the challenges now facing dental schools? The purpose of this article is to pose questions and suggestions regarding some of the key issues in dental colleges today and to stimulate discussion in the dental community about needed changes in dental education.

  8. Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal

    DEFF Research Database (Denmark)

    Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

    2016-01-01

    , and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character......Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case...... also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication. The objective is addressed in a literature review and a case study. The literature...

  9. Iterative key-residues interrogation of a phytase with thermostability increasing substitutions identified in directed evolution.

    Science.gov (United States)

    Shivange, Amol V; Roccatano, Danilo; Schwaneberg, Ulrich

    2016-01-01

    Bacterial phytases have attracted industrial interest as animal feed supplement due to their high activity and sufficient thermostability (required for feed pelleting). We devised an approach named KeySIDE,  an iterative Key-residues interrogation of the wild type with Substitutions Identified in Directed Evolution for improving Yersinia mollaretii phytase (Ymphytase) thermostability by combining key beneficial substitutions and elucidating their individual roles. Directed evolution yielded in a discovery of nine positions in Ymphytase and combined iteratively to identify key positions. The "best" combination (M6: T77K, Q154H, G187S, and K289Q) resulted in significantly improved thermal resistance; the residual activity improved from 35 % (wild type) to 89 % (M6) at 58 °C and 20-min incubation. Melting temperature increased by 3 °C in M6 without a loss of specific activity. Molecular dynamics simulation studies revealed reduced flexibility in the loops located next to helices (B, F, and K) which possess substitutions (Helix-B: T77K, Helix-F: G187S, and Helix-K: K289E/Q). Reduced flexibility in the loops might be caused by strengthened hydrogen bonding network (e.g., G187S and K289E/K289Q) and a salt bridge (T77K). Our results demonstrate a promising approach to design phytases in food research, and we hope that the KeySIDE might become an attractive approach for understanding of structure-function relationships of enzymes.

  10. Integrating Variable Renewable Energy into the Grid: Key Issues, Greening the Grid (Spanish Version)

    Energy Technology Data Exchange (ETDEWEB)

    2016-04-01

    This is the Spanish version of 'Greening the Grid - Integrating Variable Renewable Energy into the Grid: Key Issues'. To foster sustainable, low-emission development, many countries are establishing ambitious renewable energy targets for their electricity supply. Because solar and wind tend to be more variable and uncertain than conventional sources, meeting these targets will involve changes to power system planning and operations. Grid integration is the practice of developing efficient ways to deliver variable renewable energy (VRE) to the grid. Good integration methods maximize the cost-effectiveness of incorporating VRE into the power system while maintaining or increasing system stability and reliability. When considering grid integration, policy makers, regulators, and system operators consider a variety of issues, which can be organized into four broad topics: New Renewable Energy Generation, New Transmission, Increased System Flexibility, and Planning for a High RE Future.

  11. Family-friendliness in business as a key issue for the future.

    Science.gov (United States)

    Stutzer, Erich

    2012-01-01

    These days family-friendliness is a key issue for the future of businesses. Investments in a family conscious personnel policy are considered as forward-looking decisions in companies. This happens against the background of a sustainable personnel policy in times of a decrease in the number of employable persons, an increasing shortage of skilled workers and an ageing workforce. Family-friendly working conditions are becoming a key factor in the competition for staff. When choosing an employer, family-friendliness has become a crucial topic. Employment participation and skills of women, especially of mothers, have greatly increased. To facilitate the realisation of their wish to return to paid employment, however, measures to reconcile work and family are required. Family-conscious measures have been proven to lead to higher employee productivity. Job satisfaction and motivation of employees and accumulation of human capital increase, absenteeism declines, the return of investment rises. Fields of activity for family-friendly measures in companies range from working arrangements, parental leave and re-entry programmes and various child care offers to services for families. In connection with the demographic development the demand for a better reconciliation of work and elder care should in future become ever more important, just as the upkeep of the occupational skills and working capacity of an ageing workforce. Family-friendliness has to become an integral part of corporate culture.

  12. Identifying Regional Key Eco-Space to Maintain Ecological Security Using GIS

    Directory of Open Access Journals (Sweden)

    Hualin Xie

    2014-02-01

    Full Text Available Ecological security and environmental sustainability are the foundations of sustainable development. With the acceleration of urbanization, increasing human activities have promoted greater impacts on the eco-spaces that maintain ecological security. Regional key eco-space has become the primary need to maintain environmental sustainability and can offer society with continued ecosystem services. In this paper, considering the security of water resources, biodiversity conservation, disaster avoidance and protection and natural recreation, an integrated index of eco-space importance was established and a method for identifying key eco-space was created using GIS, with Lanzhou City, China as a case study. The results show that the area of core eco-space in the Lanzhou City is approximately 50,908.7 hm2, accounting for 40% of the region’s total area. These areas mainly consist of geological hazard protection zones and the core zones of regional river systems, wetlands, nature reserves, forest parks and scenic spots. The results of this study provide some guidance for the management of ecological security, ecological restoration and environmental sustainability.

  13. eHealth Literacy and Health Behaviors Affecting Modern College Students: A Pilot Study of Issues Identified by the American College Health Association.

    Science.gov (United States)

    Britt, Rebecca Katherine; Collins, William Bart; Wilson, Kari; Linnemeier, Georgiann; Englebert, Andrew Mark

    2017-12-19

    The eHealth Literacy Scale (eHEALS) has been widely adopted by researchers to understand how eHealth literacy can be put into context. eHealth researchers need to know how to promote positive health behavior changes across college students, given the importance of the Internet to acquire and use health information. The American College Health Association identified a set of key health issues that affect college students today. By understanding how eHEALS might be related to college students' maintenance of their health and their use of online health resources, researchers will be provided with a better understanding of eHealth literacy and its pragmatic implications for health campaigns and future interventions. The goal of the study was to examine what eHEALS reveals about college student health behaviors identified by the American College Health Association. To understand college student current health maintenance and their intentions to maintain their health and use online resources, the theory of planned behavior was used as the theoretical framework for the study. Data were collected via a survey of 422 college students that included the eHEALS measure and questions about health issues based on the recommendations of the American College Health Association. These questions asked about college student current health, subsequent use of online health resources, and their intention to maintain their health and make use of such resources in the future. eHEALS was positively and significantly associated with all 8 areas of health issues identified by the American College Health Association for college student current maintenance of health and use of online health resources and for future intention of health maintenance and use of online resources. Key issues that emerged with eHealth literacy were maintaining safe sex practices and seeking out related information, seeking out information on an exercise regime, information on vaccinations, and maintaining a balanced

  14. Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

    Science.gov (United States)

    Parker, Miles; Acland, Andrew; Armstrong, Harry J; Bellingham, Jim R; Bland, Jessica; Bodmer, Helen C; Burall, Simon; Castell, Sarah; Chilvers, Jason; Cleevely, David D; Cope, David; Costanzo, Lucia; Dolan, James A; Doubleday, Robert; Feng, Wai Yi; Godfray, H Charles J; Good, David A; Grant, Jonathan; Green, Nick; Groen, Arnoud J; Guilliams, Tim T; Gupta, Sunjai; Hall, Amanda C; Heathfield, Adam; Hotopp, Ulrike; Kass, Gary; Leeder, Tim; Lickorish, Fiona A; Lueshi, Leila M; Magee, Chris; Mata, Tiago; McBride, Tony; McCarthy, Natasha; Mercer, Alan; Neilson, Ross; Ouchikh, Jackie; Oughton, Edward J; Oxenham, David; Pallett, Helen; Palmer, James; Patmore, Jeff; Petts, Judith; Pinkerton, Jan; Ploszek, Richard; Pratt, Alan; Rocks, Sophie A; Stansfield, Neil; Surkovic, Elizabeth; Tyler, Christopher P; Watkinson, Andrew R; Wentworth, Jonny; Willis, Rebecca; Wollner, Patrick K A; Worts, Kim; Sutherland, William J

    2014-01-01

    Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics) elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security.

  15. Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

    Directory of Open Access Journals (Sweden)

    Miles Parker

    Full Text Available Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security.

  16. Identifying the Science and Technology Dimensions of Emerging Public Policy Issues through Horizon Scanning

    Science.gov (United States)

    Parker, Miles; Acland, Andrew; Armstrong, Harry J.; Bellingham, Jim R.; Bland, Jessica; Bodmer, Helen C.; Burall, Simon; Castell, Sarah; Chilvers, Jason; Cleevely, David D.; Cope, David; Costanzo, Lucia; Dolan, James A.; Doubleday, Robert; Feng, Wai Yi; Godfray, H. Charles J.; Good, David A.; Grant, Jonathan; Green, Nick; Groen, Arnoud J.; Guilliams, Tim T.; Gupta, Sunjai; Hall, Amanda C.; Heathfield, Adam; Hotopp, Ulrike; Kass, Gary; Leeder, Tim; Lickorish, Fiona A.; Lueshi, Leila M.; Magee, Chris; Mata, Tiago; McBride, Tony; McCarthy, Natasha; Mercer, Alan; Neilson, Ross; Ouchikh, Jackie; Oughton, Edward J.; Oxenham, David; Pallett, Helen; Palmer, James; Patmore, Jeff; Petts, Judith; Pinkerton, Jan; Ploszek, Richard; Pratt, Alan; Rocks, Sophie A.; Stansfield, Neil; Surkovic, Elizabeth; Tyler, Christopher P.; Watkinson, Andrew R.; Wentworth, Jonny; Willis, Rebecca; Wollner, Patrick K. A.; Worts, Kim; Sutherland, William J.

    2014-01-01

    Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique [1]. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics) elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security. PMID:24879444

  17. Offshore wind power experiences, potential and key issues for deployment

    Energy Technology Data Exchange (ETDEWEB)

    Lemming, J.; Morthorst, P.E.; Clausen, Niels-Erik

    2009-01-15

    Wind power has been growing at spectacular rates. Today it is the largest non-hydro renewable power technology. Worldwide there is 74 GW of installed capacity which is 1.7% of power generation capacity and in 2006 it accounted for 0.82% of electricity production. However, offshore wind still only counts for a very small amount and development has only taken place in North European counties round the North Sea and the Baltic Sea over the last 15 years. Offshore wind is still some 50% more expensive than onshore wind, but more wind resources and lesser visual impacts from larger turbines are expected to compensate for the higher installation costs in the long term. Most offshore wind farms are installed in British, Swedish and Danish waters, and present-day costs of installing wind energy in the UK are between 1,200 to 1,600 GBP/kW (1,781 to 2,375 Euro/kW) offshore, while in Sweden investment costs were 1,800 Euro/kW, and in Denmark 1,200 to 1,700 Euro/kW, though investment costs for a new wind farm are expected be in the range of 2.0 to 2.2 mill. Euro/MW for a near-shore shallow depth facility. Future developments in offshore wind technology concerning aerodynamics, structural dynamics, structural design, machine elements, electrical design and grid integration could drive investment costs from present-day range of 1.9 to 2.2 mill. Euro/MW down to 1.35 - 1.54 mill.Euro/MW in 2050, which accounts for a reduction of costs of approx. 35%. In order to sum up progress and identify future research needs, the International Energy Agency (IEA) Wind agreement Task 11 should arrange a new meeting concerning long term research needs for reviewing 'the long term strategy for 2000 to 2020' from 2001, to come up with suggestions / recommendations on how to define and proceed with, the necessary research activities of the IEA Wind Agreement and governments involved on key wind issues related to offshore technologies. (au)

  18. Key issues concerning changes in the radiological protection system: some thoughts from the French Society for Radiation Protection (SFRP)

    International Nuclear Information System (INIS)

    Schieber, C.; Cordoliani, Y.S.

    2002-01-01

    In 1999, the International Radiological Protection Association (IRPA) asked for contributions to the debate on future changes to the radiological protection system proposed by the International Commission on Radiological Protection (ICRP). In response, the Board of the French Society for Radiation Protection (SFRP) created a working group to deal specifically with this issue. It met on several occasions between April and July and its findings were presented at the IRPA Congress in May 2000. They were also published in the French journal Radioprotection and in the British Journal of Radiological Protection. To further its discussions, the Board of the SFRP decided to create a second working group which became operational in September 2001. It has around 20 members representing the major players in the radiological protection field in France: authorities, experts and professionals from the nuclear, medical and research fields as well as one association representative (the list of members can be found at the end of this document). The working group was set up to produce proposals relating to the key issues likely to be raised, particularly by the ICRP, concerning the development of new radiological protection recommendations. The members of the working group analysed the ICRP memorandum published in the June 2001 edition of the Journal of Radiological Protection and used their own experience to determine what these key issues would be. The following issues were discussed: General thoughts on the new radiological protection system proposed by the ICRP, Individual and collective approaches to the radiological risk, Comparison with chemical risk management, Radiological protection of the environment, Changes in exposure levels and units of measurement. This paper, which has been approved by the Board of the SFRP, gives the main conclusions of the working group on the key issues in these areas. It is intended to reflect the various opinions expressed during the groups

  19. Fertility Preservation: A Key Survivorship Issue for Young Women with Cancer

    Science.gov (United States)

    Angarita, Ana Milena; Johnson, Cynae A.; Fader, Amanda Nickles; Christianson, Mindy S.

    2016-01-01

    Fertility preservation in the young cancer survivor is recognized as a key survivorship issue by the American Society of Clinical Oncology and the American Society of Reproductive Medicine. Thus, health-care providers should inform women about the effects of cancer therapy on fertility and should discuss the different fertility preservation options available. It is also recommended to refer women expeditiously to a fertility specialist in order to improve counseling. Women’s age, diagnosis, presence of male partner, time available, and preferences regarding use of donor sperm influence the selection of the appropriate fertility preservation option. Embryo and oocyte cryopreservation are the standard techniques used while ovarian tissue cryopreservation is new, yet promising. Despite the importance of fertility preservation for cancer survivors’ quality of life, there are still communication and financial barriers faced by women who wish to pursue fertility preservation. PMID:27200291

  20. Fertility preservation: A key survivorship issue for young women with cancer

    Directory of Open Access Journals (Sweden)

    Ana M Angarita

    2016-04-01

    Full Text Available Fertility preservation in the young cancer survivor is recognized as a key survivorship issue by the American Society of Clinical Oncology and the American Society of Reproductive Medicine. Thus, health care providers should inform women about the effects of cancer therapy on fertility and should discuss the different fertility preservation options available. It is also recommended to refer women expeditiously to a fertility specialist in order to improve counseling. Women’s age, diagnosis, presence of male partner, time available and preferences regarding use of donor sperm influence the selection of the appropriate fertility preservation option. Embryo and oocyte cryopreservation are the standard techniques used while ovarian tissue cryopreservation is new, yet promising. Despite the importance of fertility preservation for cancer survivors’ quality of life, there are still communication and financial barriers faced by women who wish to pursue fertility preservation.

  1. Key process issues in Cognitive Behavioral Analysis System of Psychotherapy (CBASP): translation of an evidence-based model into clinical practice and training.

    Science.gov (United States)

    Vivian, Dina; Salwen, Jessica

    2013-09-01

    Our "desired outcome" in writing this article was to present not only key process issues stemming from the Cognitive Behavioral Analysis System of Psychotherapy (CBASP; McCullough, 2000), but to highlight those therapy maneuvers that we, a "seasoned" clinician/supervisor and a clinical trainee, find most useful in delivering treatment and in conducting supervision. We strongly believe that it is only through the translation of evidence-based therapeutic models, such as CBASP, into effective training that a true integration of science and practice can be obtained. Thus, the congruence of trainer's and trainee's views on what constitute top process issues in therapy is important in evaluating the reliability of a therapy model; with this in mind, we focus on three process issues, as follows: (1) problems are anchored to the "here and now" and to specific situational outcomes; (2) patients are encouraged to identify the role they play in affecting their distressing outcomes and to take responsibility for "fixing" them; and (3) the therapist planfully engages in the process of change via disciplined personal involvement. Research and theory supporting these maneuvers are presented, in conjunction with clinical examples. 2013 APA, all rights reserved

  2. The challenge of spin–orbit-tuned ground states in iridates: a key issues review

    Science.gov (United States)

    Cao, Gang; Schlottmann, Pedro

    2018-04-01

    Effects of spin–orbit interactions in condensed matter are an important and rapidly evolving topic. Strong competition between spin–orbit, on-site Coulomb and crystalline electric field interactions in iridates drives exotic quantum states that are unique to this group of materials. In particular, the ‘J eff  =  ½’ Mott state served as an early signal that the combined effect of strong spin–orbit and Coulomb interactions in iridates has unique, intriguing consequences. In this Key Issues Review, we survey some current experimental studies of iridates. In essence, these materials tend to defy conventional wisdom: absence of conventional correlations between magnetic and insulating states, avoidance of metallization at high pressures, ‘S-shaped’ I–V characteristic, emergence of an odd-parity hidden order, etc. It is particularly intriguing that there exist conspicuous discrepancies between current experimental results and theoretical proposals that address superconducting, topological and quantum spin liquid phases. This class of materials, in which the lattice degrees of freedom play a critical role seldom seen in other materials, evidently presents some profound intellectual challenges that call for more investigations both experimentally and theoretically. Physical properties unique to these materials may help unlock a world of possibilities for functional materials and devices. We emphasize that, given the rapidly developing nature of this field, this Key Issues Review is by no means an exhaustive report of the current state of experimental studies of iridates.

  3. Identifying Key Stakeholder Groups for Implementing a Place Branding Policy in Saint Petersburg

    Directory of Open Access Journals (Sweden)

    Kulibanova V. V.

    2017-10-01

    Full Text Available Regional brands have become a valuable intangible asset and a crucial competitive resource for forging partnerships. An effective place branding policy is impossible without a precise understanding of the interests of stakeholder groups. It is essential to realize that each region is unique in its own way. Territories differ in the structure of stakeholders, their influence on regional development, and the range of leverages over regional decision-makers. This study aims to give a more precise definition of key groups of stakeholders in Saint Petersburg place branding, and to identify them. The authors employ the method of theoretical and empirical typology of a territory’s stakeholders within a theoretical framework proposed by E. Freeman, P. Kotler, S. Zenker, and E. Brown. The article defines the concept of key regional stakeholders and identifies them. The proposed target audience (stakeholder group model for a place branding policy is tested on the case of Saint Petersburg. The authors show that each target audience of place marketing requires an individual policy. This is explained by the fact that each group enjoys its unique features that should be taken into account when creating and transmitting messages.

  4. Development of regulatory technologies of key issues of radiation sources in the medical and industrial fields

    International Nuclear Information System (INIS)

    Lee, Jae Seong; Kim, Byung Soo; Ku, Bon Chul

    2006-08-01

    The aim of this research is to provide with rational bases to address the key issues raising up during the expansion of RI/RG usage in the medical and industrial fields, thus eventually contribute to enhancing the effectiveness of national regulatory systems. Related key issues that are introduced in the medical and industrial fields are analyzed and some outcomes are produced. The following results are attained. - Estimation Methodology Development of Regulatory Effects for the Use of Radioactive Substances, - Survey on Domestic Status of Nuclear Materials and Review on Domestic/Foreign Regulatory System for Nuclear Materials Regulation, - Comparative Analysis of KSTAR and Fusion Facilities of Advanced Countries, - Radiological Characteristics of Proton Therapy and Analysis of Foreign Cases and Systems, - Detection and Safety Analysis of Leak Radiation of High Energy Medical Generators, - Survey and Analysis on Usage and Requirements of Sealed Sources, - Incidents/Accidents Reporting System for RI-related Facilities, - Development of Audio-Visual Education Materials for Radiation Workers, - Development of Major Safety Procedures for Portable RIs, - Expansion of Existing DB for Radiation Devices including New Domestic Ones, - Survey of Foreign Status of Quality Maintenance System for Radiation equipment

  5. Framework for Identifying Key Environmental Concerns in Marine Renewable Energy Projects- Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, Sharon; Previsic, Mirko; Nelson, Peter; Woo, Sheri

    2010-06-17

    Marine wave and tidal energy technology could interact with marine resources in ways that are not well understood. As wave and tidal energy conversion projects are planned, tested, and deployed, a wide range of stakeholders will be engaged; these include developers, state and federal regulatory agencies, environmental groups, tribal governments, recreational and commercial fishermen, and local communities. Identifying stakeholders’ environmental concerns in the early stages of the industry’s development will help developers address and minimize potential environmental effects. Identifying important concerns will also assist with streamlining siting and associated permitting processes, which are considered key hurdles by the industry in the U.S. today. In September 2008, RE Vision consulting, LLC was selected by the Department of Energy (DoE) to conduct a scenario-based evaluation of emerging hydrokinetic technologies. The purpose of this evaluation is to identify and characterize environmental impacts that are likely to occur, demonstrate a process for analyzing these impacts, identify the “key” environmental concerns for each scenario, identify areas of uncertainty, and describe studies that could address that uncertainty. This process is intended to provide an objective and transparent tool to assist in decision-making for siting and selection of technology for wave and tidal energy development. RE Vision worked with H. T. Harvey & Associates, to develop a framework for identifying key environmental concerns with marine renewable technology. This report describes the results of this study. This framework was applied to varying wave and tidal power conversion technologies, scales, and locations. The following wave and tidal energy scenarios were considered: 4 wave energy generation technologies 3 tidal energy generation technologies 3 sites: Humboldt coast, California (wave); Makapu’u Point, Oahu, Hawaii (wave); and the Tacoma Narrows, Washington (tidal

  6. Information for Government Agencies about Specific Environmental Health Issues in Child-Care Settings

    Science.gov (United States)

    research on child care environmental health issues, identify key state and regional healthy child care organizations for partnerships, and see how other states are addressing child care environmental health issues.

  7. Experimental Study and Computational Simulations of Key Pebble Bed Thermo-mechanics Issues for Design and Safety

    Energy Technology Data Exchange (ETDEWEB)

    Tokuhiro, Akira; Potirniche, Gabriel; Cogliati, Joshua; Ougouag, Abderrafi

    2014-07-08

    An experimental and computational study, consisting of modeling and simulation (M&S), of key thermal-mechanical issues affecting the design and safety of pebble-bed (PB) reactors was conducted. The objective was to broaden understanding and experimentally validate thermal-mechanic phenomena of nuclear grade graphite, specifically, spheres in frictional contact as anticipated in the bed under reactor relevant pressures and temperatures. The contact generates graphite dust particulates that can subsequently be transported into the flowing gaseous coolent. Under postulated depressurization transients and with the potential for leaked fission products to be adsorbed onto graphite 'dust', there is the potential for fission products to escape from the primary volume. This is a design safety concern. Furthermore, earlier safety assessment identified the distinct possibility for the dispersed dust to combust in contact with air if sufficient conditions are met. Both of these phenomena were noted as important to design review and containing uncertainty to warrant study. The team designed and conducted two separate effects tests to study and benchmark the potential dust-generation rate, as well as study the conditions under which a dust explosion may occure in a standardized, instrumented explosion chamber.

  8. Trends between 1973 and 1988: Summary and key issues

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The preceding chapters considered the evolution of activity, structure, energy intensity, and energy use between the early 1970s and 1988 for the manufacturing, transportation, residential, and service sectors. In this chapter, the author summarizes the changes that have taken place, and presents results of a cross-sectoral analysis of the effect of change in sectoral activity, structure, and energy intensity on energy use in the three largest OECD economies: the United States, Japan, and West Germany. He also addresses a number of key issues that have important implications for future energy use in the OECD countries and elsewhere. Between 1973 and 1988, final energy use in the five sectors studied (which account for around 90% of total energy use) grew by 3% in the United, States, 15% in Japan, and 3% in West Germany. Energy use in manufacturing declined by 10-20% in each country. Energy use for passenger travel grew by only 11% in the United States, but rose by 76% in Japan and by 56% in West Germany. There was moderate to strong growth in freight energy use in all three countries. There was very high growth in residential and services energy use in Japan, and moderate growth in these sectors in the United States and West Germany. 12 refs., 5 figs., 3 tabs

  9. Quantum oscillations and key theoretical issues in high temperature superconductors from the perspective of density waves

    International Nuclear Information System (INIS)

    Chakravarty, Sudip

    2011-01-01

    High temperature superconductivity in cuprate superconductors remains an unsolved problem in theoretical physics. The same statement can also be made about a number of other superconductors that have been dubbed novel. What makes these superconductors so elusive is an interesting question in itself. This paper focuses on the recent magnetic oscillation experiments and how they fit into the broader picture. Many aspects of these experiments can be explained by Fermi liquid theory; the key issue is the extent to which this is true. If true, the entire paradigm developed over the past three decades must be reexamined. A critical analysis of this issue has necessitated a broader analysis of questions about distinct ground states of matter, which may be useful in understanding other novel superconductors.

  10. Water resources and environmental input-output analysis and its key study issues: a review

    Science.gov (United States)

    YANG, Z.; Xu, X.

    2013-12-01

    Used to study the material and energy flow in socioeconomic system, Input-Output Analysis(IOA) had been an effective analysis tool since its appearance. The research fields of Input-Output Analysis were increasingly expanded and studied in depth with the development of fundamental theory. In this paper, starting with introduction of theory development, the water resources input-output analysis and environmental input-output analysis had been specifically reviewed, and two key study issues mentioned as well. Input-Occupancy-Output Analysis and Grey Input-Output Analysis whose proposal and development were introduced firstly could be regard as the effective complements of traditional IOA theory. Because of the hypotheses of homogeneity, stability and proportionality, Input-Occupancy-Output Analysis and Grey Input-Output Analysis always had been restricted in practical application inevitably. In the applied study aspect, with investigation of abundant literatures, research of water resources input-output analysis and environmental input-output analysis had been comprehensively reviewed and analyzed. The regional water resources flow between different economic sectors had been systematically analyzed and stated, and several types of environmental input-output analysis models combined with other effective analysis tools concluded. In two perspectives in terms of external and inland aspect, the development of water resources and environmental input-output analysis model had been explained, and several typical study cases in recent years listed respectively. By the aid of sufficient literature analysis, the internal development tendency and study hotspot had also been summarized. In recent years, Chinese literatures reporting water resources consumption analysis and virtue water study had occupied a large share. Water resources consumption analysis had always been the emphasis of inland water resources IOA. Virtue water study had been considered as the new hotspot of

  11. Identifying and weighting of key performance indicators of knowledge management2.0 in organizations

    Directory of Open Access Journals (Sweden)

    Saeed Khalilazar

    2016-03-01

    Full Text Available Main purpose of this research is identifying and weighting of key performance indicators of knowledge management2.0 in organizations. According to widespread permeation of technology, especially social media in different organizational dimensions and functional view to this phenomenon in knowledge management, performance measurement of this kind of media in order to meet organizational goals seems necessary. KM2.0 key performance indicators in this article has been identified and weighted through Delphi methodology, via questionnaire in three rounds. KM2.0 KPIs which are identified and weighted in this article are applicable in organizations that are eager to implement KM2.0 initiative and they can measure the performance of KM2.0 activities therefore this research is applicable in goal oriented approach. According to the results, KM2.0 participation process consists of 3 stages and 8 steps as mentioned below: First stage which is presence, consists of 3 steps which are registration, visit and download. Second stage which is feedback consists of 3 steps which are conversation, applause and amplification. Finally, third stage which is creation consists of 2 steps which are codification and personalization. Ultimate contribution of this research is identifying and weighting KPIs of KM2.0 in conceptual framework of KM2.0. Based on developing a conceptual framework and participation process in KM2.0 and listing related KPIs as an applicable solution in order to measure and improve the performance of organizational social media, this research has unique innovation among related and other articles.

  12. Plutonium: key issue in nuclear disarmament and non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Yoshisaki, M.B.

    1993-01-01

    The technical report is a 1993 update on weapons-grade plutonium, a key issue in nuclear disarmament. Its vital significance would again be discussed during the fifth and the last Review Conference on the Non-Proliferation Treaty (NPT) for Nuclear Weapons which would end in 1995. Member States shall decide whether an indefinite or conditional extension of NPT is necessary for world peace and international security. Two Non-NPT States, Russia and U.S.A. are in the forefront working for the reduction of nuclear weapons through nuclear disarmament. Their major effort is focused on the implementation of the Strategic Arms Reduction Treaty I and II or START I and II for world peace. The eventual implementation of START I and II would lead to the dismantling of plutonium from nuclear warheads proposed to be eliminated by both countries. This report gives three technical options to be derived from nuclear disarmament issues for the non-proliferation of nuclear weapons: (a) indefinite storage - there is no guarantee that these will not be used in the future (b) disposal as wastes - possible only in principle, because of lack of experience in mixing plutonium with high level wastes, and (c) source of energy - best option in managing stored weapons materials, because it satisfies non-proliferation objectives. It means fuel for energy in Light Water Reactors (LWR) or Fast Breeder Reactors (FBR). (author). 8 refs

  13. Identifying and characterizing key nodes among communities based on electrical-circuit networks.

    Science.gov (United States)

    Zhu, Fenghui; Wang, Wenxu; Di, Zengru; Fan, Ying

    2014-01-01

    Complex networks with community structures are ubiquitous in the real world. Despite many approaches developed for detecting communities, we continue to lack tools for identifying overlapping and bridging nodes that play crucial roles in the interactions and communications among communities in complex networks. Here we develop an algorithm based on the local flow conservation to effectively and efficiently identify and distinguish the two types of nodes. Our method is applicable in both undirected and directed networks without a priori knowledge of the community structure. Our method bypasses the extremely challenging problem of partitioning communities in the presence of overlapping nodes that may belong to multiple communities. Due to the fact that overlapping and bridging nodes are of paramount importance in maintaining the function of many social and biological networks, our tools open new avenues towards understanding and controlling real complex networks with communities accompanied with the key nodes.

  14. Modelling Creativity: Identifying Key Components through a Corpus-Based Approach.

    Science.gov (United States)

    Jordanous, Anna; Keller, Bill

    2016-01-01

    Creativity is a complex, multi-faceted concept encompassing a variety of related aspects, abilities, properties and behaviours. If we wish to study creativity scientifically, then a tractable and well-articulated model of creativity is required. Such a model would be of great value to researchers investigating the nature of creativity and in particular, those concerned with the evaluation of creative practice. This paper describes a unique approach to developing a suitable model of how creative behaviour emerges that is based on the words people use to describe the concept. Using techniques from the field of statistical natural language processing, we identify a collection of fourteen key components of creativity through an analysis of a corpus of academic papers on the topic. Words are identified which appear significantly often in connection with discussions of the concept. Using a measure of lexical similarity to help cluster these words, a number of distinct themes emerge, which collectively contribute to a comprehensive and multi-perspective model of creativity. The components provide an ontology of creativity: a set of building blocks which can be used to model creative practice in a variety of domains. The components have been employed in two case studies to evaluate the creativity of computational systems and have proven useful in articulating achievements of this work and directions for further research.

  15. Ten key issues in modern flow chemistry.

    Science.gov (United States)

    Wegner, Jens; Ceylan, Sascha; Kirschning, Andreas

    2011-04-28

    Ten essentials of synthesis in the flow mode, a new enabling technology in organic chemistry, are highlighted as flashlighted providing an insight into current and future issues and developments in this field. © The Royal Society of Chemistry 2011

  16. Identifying key areas for active interprofessional learning partnerships: A facilitated dialogue.

    Science.gov (United States)

    Steven, Kathryn; Angus, Allyson; Breckenridge, Jenna; Davey, Peter; Tully, Vicki; Muir, Fiona

    2016-11-01

    Student and service user involvement is recognised as an important factor in creating interprofessional education (IPE) opportunities. We used a team-based learning approach to bring together undergraduate health professional students, early career professionals (ECPs), public partners, volunteers, and carers to explore learning partnerships. Influenced by evaluative inquiry, this qualitative study used a free text response to allow participants to give their own opinion. A total of 153 participants (50 public partners and 103 students and professionals representing 11 healthcare professions) took part. Participants were divided into mixed groups of six (n = 25) and asked to identify areas where students, professionals, and public could work together to improve health professional education. Each group documented their discussions by summarising agreed areas and next steps. Responses were collected and transcribed for inductive content analysis. Seven key themes (areas for joint working) were identified: communication, public as partners, standards of conduct, IPE, quality improvement, education, and learning environments. The team-based learning format enabled undergraduate and postgraduate health professionals to achieve consensus with public partners on areas for IPE and collaboration. Some of our results may be context-specific but the approach is generalisable to other areas.

  17. Key issues on safety design basis selection and safety assessment

    International Nuclear Information System (INIS)

    An, S.; Togo, Y.

    1976-01-01

    In current fast reactor design in Japan, four design accident conditions and four design seismic conditions are adopted as the design base classifications. These are classified by the considerations on both likelihood of occurrence and the severeness of the consequences. There are several major problem areas in safety design consideration such as core accident problems which include fuel sodium interaction, fuel failure propagation and residual decay heat removal, and decay heat removal systems problems which is more or less the problem of selection of appropriate system and of assurance of high reliability of the system. In view of licensing, two kinds of accidents are postulated in evaluating the adequacy of a reactor site. The one is the ''major accident'' which is the accident to give most severe radiation hazard to the public from technical point of view. The other is the ''hypothetical accident'', induced public accident of which is severer than that of major accident. While the concept of the former is rather unique to Japanese licensing, the latter is almost equivalent to design base hypothetical accident of the US practice. In this paper, design bases selections, key safety issues and some of the licensing considerations in Japan are described

  18. Using in-depth investigations to identify transportation safety issues for wheelchair-seated occupants of motor vehicles.

    Science.gov (United States)

    Schneider, Lawrence W; Klinich, Kathleen D; Moore, Jamie L; MacWilliams, Joel B

    2010-04-01

    In-depth investigations of motor-vehicle crashes involve detailed inspection, measurement, and photodocumentation of vehicle exterior and interior damage, evidence of belt-restraint use, and evidence of occupant contacts with the vehicle interior. Results of in-depth investigations thereby provide the most objective way to identify current and emerging injury problems and issues in occupant safety and crash protection, and provide important feedback on the real-world performance of the latest restraint-system and vehicle crashworthiness technologies. To provide an objective understanding of real-world transportation safety issues for wheelchair-seated travelers, the University of Michigan Transportation Research Institute (UMTRI) has been conducting and assembling data from in-depth investigations of motor-vehicle crashes and non-crash adverse moving-vehicle incidents, such as emergency vehicle braking, turning, and swerving, in which there was at least one vehicle occupant sitting in a wheelchair. The results of 39 investigations involving 42 wheelchair-seated occupants have been assembled and entered into a wheelchair-occupant crash/injury database. In addition, a biomechanical analysis of each case has been performed to identify key safety issues for wheelchair-seated travelers. The wheelchairs of 34 of the 42 occupants who were seated in wheelchairs while traveling in motor vehicles were effectively secured by either a four-point, strap-type tiedown system or a docking securement device, and all but one of these properly secured wheelchairs remained in place during the crash or non-collision event. However, 30 of the 42 occupants were improperly restrained, either because of non-use or incomplete use of available belt restraints, or because the belt restraints were improperly positioned on the occupant's body. Twenty-six of the 42 occupants sustained significant injuries and 10 of these occupants died as a direct result of injuries sustained, or from

  19. An Investigation of Information Technology-Enabled Remote Management and Remote Work Issues

    Directory of Open Access Journals (Sweden)

    D. Sandy Staples

    1997-05-01

    Full Text Available A two phase research study was done to investigate remote work and remote management issues. In Phase 1, focus groups were carried out with remote managers and remote employees to identify key issues. The most common key issues dealt with communications, information technology, leadership and coaching, teamwork, building trust, and performance management. In the second phase, a questionnaire was used to test hypotheses developed from phase 1. The findings supported that higher trust leads to higher job satisfaction and lower job stress, and that more communication between the manager and the remote employee develops higher levels of employee organizational commitment.

  20. Socioeconomic issues and analyses for radioactive waste disposal facilities

    International Nuclear Information System (INIS)

    Ulland, L.

    1988-01-01

    Radioactive Waste facility siting and development can raise major social and economic issues in the host area. Initial site screening and analyses have been conducted for both potential high-level and low-level radioactive waste facilities; more detailed characterization and analyses are being planned. Results of these assessments are key to developing community plans that identify and implement measures to mitigate adverse socioeconomic impacts. Preliminary impact analyses conducted at high-level sites in Texas and Nevada, and site screening activities for low-level facilities in Illinois and California have identified a number of common socioeconomic issues and characteristics as well as issues and characteristics that differ between the sites and the type of facilities. Based on these comparisons, implications for selection of an appropriate methodology for impact assessment and elements of impact mitigation are identified

  1. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (Volume 1) (Interagency Science Discussion Draft)

    Science.gov (United States)

    EPA is releasing the draft report, EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (Volume 1), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the BIOPROTA Key Issues in Biosphere Aspects of Assessment of the Long-term Impact of Contaminant Releases Associated with Radioactive Waste Management. Theme 2: Task 7: Modelling Processes in the Geosphere Biosphere Interface Zone

    International Nuclear Information System (INIS)

    Pinedo, P.; Smith, G.; Aguero, A.; Albrecht, A.; Bath, A.; Benhabderrahmane, H.; Van Dorp, F.; Kautsky, U.; Klos, R.; Laciok, A.; Milodowski, T.; Selroos, J.O.; Simon, I.; Texier, D.; Thorne, M.; Willans, M.

    2005-01-01

    This document reports on BIOPROTA Theme 2, task 7 which investigated modelling processes in the geosphere- biosphere interface zone (GBIZ) during performance assessments. Modelling issues in the treatment of the GBIZ are identified. A large proportion of the identified issues concern modelling radionuclide behaviour in near surface aquifers which are subject to relatively high gradients in chemical and other conditions. Other key issues concern transfer of radionuclides through the unsaturated zone above aquifers, bearing in mind the scope for erosion and variations in the level of the phreatic surface and also the consideration of environmental change. A number of research areas are highlighted that are aimed at addressing each of the identified issues in the treatment of GBIZ. These include (i) Developing of a current statement of continuing problems, and hence clarify and justify the need to do more; (ii) Conducting a review of site investigations as they have been done already, and determine whether they meet performance assessment requirements; (iii) Identifying scenarios and FEPs considered in current treatments; and, (iv) Conducting source-pathway-receptor analysis to demonstrate comprehensiveness of the overall scenario identification process. The objectives of these activities would be to determine the potential to reduce uncertainties and/or conservative assumptions in assessment of radionuclide transfer from the geosphere to biosphere domains, taking account of environmental change; and to develop guidance on site-characterisation needs at different types of site, as regards the near-surface features. (Author) 23 refs

  2. BIOPROTA Key Issues in Biosphere Aspects of Assessment of the Long-term Impact of Contaminant Releases Associated with Radioactive Waste Management Theme 2: Task 7:Modelling Processes in the Geosphere Biosphere Interface Zone

    Energy Technology Data Exchange (ETDEWEB)

    Pinedo, P.; Smith, G.; Aguero, A.; Albrecht, A.; Bath, A.; Benhabderrahmane, H.; Van Dorp, F.; Kautsky, U.; Klos, R.; Laciok, A.; Milodowski, T.; Selroos, J.O.; Simon, I.; Texier, D.; Thorne, M.; Willans, M.

    2005-07-01

    This document reports on BIOPROTA Theme 2, task 7 which investigated modelling processes in the geosphere- biosphere interface zone (GBIZ) during performance assessments. Modelling issues in the treatment of the GBIZ are identified. A large proportion of the identified issues concern modelling radionuclide behaviour in near surface aquifers which are subject to relatively high gradients in chemical and other conditions. Other key issues concern transfer of radionuclides through the unsaturated zone above aquifers, bearing in mind the scope for erosion and variations in the level of the phreatic surface and also the consideration of environmental change. A number of research areas are highlighted that are aimed at addressing each of the identified issues in the treatment of GBIZ. These include (i) Developing of a current statement of continuing problems, and hence clarify and justify the need to do more; (ii) Conducting a review of site investigations as they have been done already, and determine whether they meet performance assessment requirements; (iii) Identifying scenarios and FEPs considered in current treatments; and, (iv) Conducting source-pathway-receptor analysis to demonstrate comprehensiveness of the overall scenario identification process. The objectives of these activities would be to determine the potential to reduce uncertainties and/or conservative assumptions in assessment of radionuclide transfer from the geosphere to biosphere domains, taking account of environmental change; and to develop guidance on site-characterisation needs at different types of site, as regards the near-surface features. (Author) 23 refs.

  3. Predicting Key Events in the Popularity Evolution of Online Information.

    Science.gov (United States)

    Hu, Ying; Hu, Changjun; Fu, Shushen; Fang, Mingzhe; Xu, Wenwen

    2017-01-01

    The popularity of online information generally experiences a rising and falling evolution. This paper considers the "burst", "peak", and "fade" key events together as a representative summary of popularity evolution. We propose a novel prediction task-predicting when popularity undergoes these key events. It is of great importance to know when these three key events occur, because doing so helps recommendation systems, online marketing, and containment of rumors. However, it is very challenging to solve this new prediction task due to two issues. First, popularity evolution has high variation and can follow various patterns, so how can we identify "burst", "peak", and "fade" in different patterns of popularity evolution? Second, these events usually occur in a very short time, so how can we accurately yet promptly predict them? In this paper we address these two issues. To handle the first one, we use a simple moving average to smooth variation, and then a universal method is presented for different patterns to identify the key events in popularity evolution. To deal with the second one, we extract different types of features that may have an impact on the key events, and then a correlation analysis is conducted in the feature selection step to remove irrelevant and redundant features. The remaining features are used to train a machine learning model. The feature selection step improves prediction accuracy, and in order to emphasize prediction promptness, we design a new evaluation metric which considers both accuracy and promptness to evaluate our prediction task. Experimental and comparative results show the superiority of our prediction solution.

  4. Predicting Key Events in the Popularity Evolution of Online Information.

    Directory of Open Access Journals (Sweden)

    Ying Hu

    Full Text Available The popularity of online information generally experiences a rising and falling evolution. This paper considers the "burst", "peak", and "fade" key events together as a representative summary of popularity evolution. We propose a novel prediction task-predicting when popularity undergoes these key events. It is of great importance to know when these three key events occur, because doing so helps recommendation systems, online marketing, and containment of rumors. However, it is very challenging to solve this new prediction task due to two issues. First, popularity evolution has high variation and can follow various patterns, so how can we identify "burst", "peak", and "fade" in different patterns of popularity evolution? Second, these events usually occur in a very short time, so how can we accurately yet promptly predict them? In this paper we address these two issues. To handle the first one, we use a simple moving average to smooth variation, and then a universal method is presented for different patterns to identify the key events in popularity evolution. To deal with the second one, we extract different types of features that may have an impact on the key events, and then a correlation analysis is conducted in the feature selection step to remove irrelevant and redundant features. The remaining features are used to train a machine learning model. The feature selection step improves prediction accuracy, and in order to emphasize prediction promptness, we design a new evaluation metric which considers both accuracy and promptness to evaluate our prediction task. Experimental and comparative results show the superiority of our prediction solution.

  5. Industrial implementation issues of Total Site Heat Integration

    International Nuclear Information System (INIS)

    Chew, Kew Hong; Klemeš, Jiří Jaromír; Wan Alwi, Sharifah Rafidah; Abdul Manan, Zainuddin

    2013-01-01

    Heat Integration has been a well-established energy conservation strategy in the industry. Total Site Heat Integration (TSHI) has received growing interest since its inception in the 90s. The methodology has been used with certain simplifications to solve TSHI problems. This paper investigates the main issues that can influence the practical implementation of TSHI in the industry. The main aim is to provide an assessment and possible guidance for future development and extension of the TSHI methodology from the industrial perspective. Several key issues have been identified as being of vital importance for the industries: design, operation, reliability/availability/maintenance, regulatory/policy and economics. Design issues to consider include plant layout, pressure drop, etc. For operation, issues such as startup and shutdown need to be considered. Reliability, availability and maintenance (RAM) are important as they directly affect the production. Relevant government policy and incentives are also important when considering the options for TSHI. Finally, a TSHI system needs to be economically viable. This paper highlights the key issues to be considered for a successful implementation of TSHI. The impacts of these issues on TS integration are summarised in a matrix, which forms a basis for an improved and closer-to-real-life implementation of the TSHI methodology. Highlights: ► Current TSHI methodology has been used for solving models with certain simplifications. ► Several issues that can influence practical implementation of TSHI are identified. ► Impacts of these issues on safety, environment and economics are evaluated. ► The findings form a basis for an improved and practical implementation of TSHI

  6. The European protocol on organ transplant: key issues.

    Science.gov (United States)

    Byk, Christian

    2009-09-01

    What is interesting in the philosophy of the European Protocol is the search of a balanced position which acknowledges the medical progress brought by organ transplants and considers the necessity to ensure that human dignity and individual freedom are respected. However, the principles adopted for such regulations at the European level leave on some major issues a great margin of appreciation to the domestic legislation. This is particularly true in areas such as defining death or consenting to organ transplants including the situation of minors and the role of the family. A last point should also be stressed regarding the European protocol: its lack of efficiency concerning a neglected but important issue: organ trafficking.

  7. Ethical issues identified by obstetrics and gynecology learners through a novel ethics curriculum.

    Science.gov (United States)

    Mejia, Rachel B; Shinkunas, Laura A; Ryan, Ginny L

    2015-12-01

    Obstetrics and gynecology (ob/gyn) is fraught with bioethical issues, the professional significance of which may vary based on clinical experience. Our objective was to utilize our novel ethics curriculum to identify ethics and professionalism issues highlighted by ob/gyn learners and to compare responses between learner levels to further inform curricular development. We introduced an integrated and dynamic ob/gyn ethics and professionalism curriculum and mixed methods analysis of 181 resulting written reflections (case observation and assessments) from third-year medical students and from first- to fourth-year ob/gyn residents. Content was compared by learner level using basic thematic analysis and summary statistics. Within the 7 major ethics and professionalism domains, learners wrote most frequently about miscellaneous ob/gyn issues such as periviability and abortion (22% of students, 20% of residents) and problematic treatment decisions (20% of students, 19% of residents) rather than professional duty, communication, justice, student-/resident-specific issues, or quality of care. The most commonly discussed ob/gyn area by both learner groups was obstetrics rather than gynecology, gynecologic oncology, or reproductive endocrinology and infertility, although residents were more likely to discuss obstetrics-related concerns than students (65% vs 48%; P = .04) and students wrote about gynecologic oncology-related concerns more frequently than residents (25% vs 6%; P = .002). In their reflections, sources of ethical value (eg, the 4 classic ethics principles, professional guidelines, and consequentialism) were cited more frequently and in greater number by students than by residents (82% of students cited at least 1 source of ethical value vs 65% of residents; P = .01). Residents disagreed more frequently with the ethical propriety of clinical management than did students (67% vs 43%; P = .005). Our study introduces an innovative and dynamic approach to an ob

  8. Ongoing ethical issues concerning authorship in biomedical journals: an integrative review.

    Science.gov (United States)

    Kornhaber, Rachel Anne; McLean, Loyola M; Baber, Rodney J

    2015-01-01

    Health professionals publishing within the field of health sciences continue to experience issues concerning appropriate authorship, which have clinical, ethical, and academic implications. This integrative review sought to explore the key issues concerning authorship from a bioethical standpoint, aiming to explore the key features of the authorship debate. Studies were identified through an electronic search, using the PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Scopus databases of peer-reviewed research, published between 2009 and 2014, limited to English language research, with search terms developed to reflect the current issues of authorship. From among the 279 papers identified, 20 research papers met the inclusion criteria. Findings were compiled and then arranged to identify themes and relationships. The review incorporated a wide range of authorship issues encompassing equal-credited authors, honorary (guest/gift) and ghost authorship, perception/experiences of authorship, and guidelines/policies. This review suggests that the International Committee of Medical Journal Editors' (ICMJE) recommended guidelines for authorship are not reflected in current authorship practices within the domain of health sciences in both low-and high-impact-factor journals. This devaluing of the true importance of authorship has the potential to affect the validity of authorship, diminish the real contributions of the true authors, and negatively affect patient care.

  9. Ongoing ethical issues concerning authorship in biomedical journals: an integrative review

    Science.gov (United States)

    Kornhaber, Rachel Anne; McLean, Loyola M; Baber, Rodney J

    2015-01-01

    Health professionals publishing within the field of health sciences continue to experience issues concerning appropriate authorship, which have clinical, ethical, and academic implications. This integrative review sought to explore the key issues concerning authorship from a bioethical standpoint, aiming to explore the key features of the authorship debate. Studies were identified through an electronic search, using the PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Scopus databases of peer-reviewed research, published between 2009 and 2014, limited to English language research, with search terms developed to reflect the current issues of authorship. From among the 279 papers identified, 20 research papers met the inclusion criteria. Findings were compiled and then arranged to identify themes and relationships. The review incorporated a wide range of authorship issues encompassing equal-credited authors, honorary (guest/gift) and ghost authorship, perception/experiences of authorship, and guidelines/policies. This review suggests that the International Committee of Medical Journal Editors’ (ICMJE) recommended guidelines for authorship are not reflected in current authorship practices within the domain of health sciences in both low-and high-impact-factor journals. This devaluing of the true importance of authorship has the potential to affect the validity of authorship, diminish the real contributions of the true authors, and negatively affect patient care. PMID:26257520

  10. Identifying the key personnel in a nurse-initiated hospital waste reduction program.

    Science.gov (United States)

    McDermott-Levy, Ruth; Fazzini, Carol

    2010-01-01

    Hospitals in the United States generate more than 6600 tons of trash a day and approximately 85% of the waste is nonhazardous solid waste such as food, cardboard, and plastic. Treatment and management of hospital waste can lead to environmental problems for the communities that receive the waste. One health system's shared governance model provided the foundation to develop a nurse-led hospital waste reduction program that focused on point-of-care waste management. Waste reduction program development required working with a variety of departments within and external to the health system. The interdisciplinary approach informed the development of the waste reduction program. This article identifies the key departments that were necessary to include when developing a hospital waste reduction program.

  11. GuiaTreeKey, a multi-access electronic key to identify tree genera in French Guiana.

    Science.gov (United States)

    Engel, Julien; Brousseau, Louise; Baraloto, Christopher

    2016-01-01

    The tropical rainforest of Amazonia is one of the most species-rich ecosystems on earth, with an estimated 16000 tree species. Due to this high diversity, botanical identification of trees in the Amazon is difficult, even to genus, often requiring the assistance of parataxonomists or taxonomic specialists. Advances in informatics tools offer a promising opportunity to develop user-friendly electronic keys to improve Amazonian tree identification. Here, we introduce an original multi-access electronic key for the identification of 389 tree genera occurring in French Guiana terra-firme forests, based on a set of 79 morphological characters related to vegetative, floral and fruit characters. Its purpose is to help Amazonian tree identification and to support the dissemination of botanical knowledge to non-specialists, including forest workers, students and researchers from other scientific disciplines. The electronic key is accessible with the free access software Xper ², and the database is publicly available on figshare: https://figshare.com/s/75d890b7d707e0ffc9bf (doi: 10.6084/m9.figshare.2682550).

  12. Identifying Crucial Issues in Climate Science

    Science.gov (United States)

    Ikeda, Motoyoshi; Greve, Ralf; Hara, Toshika; Watanabe, Yutaka W.; Ohmura, Atsumu; Ito, Akihiko; Kawamiya, Michio

    2009-01-01

    Drastic Change in the Earth System During Global Warming; Sapporo, Japan, 24 June 2008; The Nobel Peace Prize awarded to the Intergovernmental Panel on Climate Change (IPCC) and former U.S. vice president Al Gore indicates that global warming is recognized as a real phenomenon critical to human beings. However, humanity's knowledge concerning global warming is based on an uncertainty larger than 50% in the warming rate during the past century. Therefore, scientific clarification is needed to understand important mechanisms that potentially produce positive feedbacks in the Earth system-such mechanisms must be better understood before scientists can develop more reliable predictions. To plan for the future, a symposium was organized at Japan's Hokkaido University in association with the G8 Summit, where the most recent updates on the five urgent issues in climate science were discussed. These issues, considered to be crucial as severe impacts on human society continue to rise, included (1) causes and magnitude of sea level rise; (2) decay of glaciers and the Greenland and Antarctic ice sheets; (3) disappearance of the summer Arctic sea ice; (4) carbon uptake or emission by the terrestrial ecosystem; and (5) marine ecosystem change resulting in carbon emissions.

  13. Liberia's Post-War Recovery: Key Issues and Developments

    National Research Council Canada - National Science Library

    Cook, Nicolas

    2006-01-01

    .... It held elections in October 2005, with a presidential run-off vote in November -- a key step in a post-conflict transition and peace-building process that began following its second civil war in a decade...

  14. "Let Me Keep My Dead Husband's Sperm": Ethical Issues in Posthumous Reproduction.

    Science.gov (United States)

    Panagiotopoulou, Nikoletta; Karavolos, Stamatios

    2015-01-01

    The feasibility of posthumous reproduction when the surviving partner is female has brought to light many ethical, moral, social, and legal issues. This review aims to summarize these issues and to assist clinicians who may be faced with such requests. A question list, used for health technologies assessment, was utilized in a question-answer approach as the review methodology. Of the 1,208 publications identified through a comprehensive literature search in biomedical, psychological, and ethical databases, 31 articles included arguments related to one or more questions from the predefined question set. Key stakeholders identified include the deceased, the requesting party, the resultant child, the physician, and society. Key ethical issues relevant to posthumous reproduction include the four traditional pillars of medical ethics--autonomy, beneficence, nonmaleficence, justice--as well as the stakeholders' rights and sociocultural attitudes. The ethical framework formulated by these issues has been incorporated in a clinical ethics decision-making tool that could prove useful to clinicians and decision makers. Copyright 2015 The Journal of Clinical Ethics. All rights reserved.

  15. Key issues of ultraviolet radiation of OH at high altitudes

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yuhuai; Wan, Tian; Jiang, Jianzheng; Fan, Jing [State Key Laboratory of High Temperature Gasdynamics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-09

    Ultraviolet (UV) emissions radiated by hydroxyl (OH) is one of the fundamental elements in the prediction of radiation signature of high-altitude and high-speed vehicle. In this work, the OH A{sup 2}Σ{sup +}→X{sup 2}Π ultraviolet emission band behind the bow shock is computed under the experimental condition of the second bow-shock ultraviolet flight (BSUV-2). Four related key issues are discussed, namely, the source of hydrogen element in the high-altitude atmosphere, the formation mechanism of OH species, efficient computational algorithm of trace species in rarefied flows, and accurate calculation of OH emission spectra. Firstly, by analyzing the typical atmospheric model, the vertical distributions of the number densities of different species containing hydrogen element are given. According to the different dominating species containing hydrogen element, the atmosphere is divided into three zones, and the formation mechanism of OH species is analyzed in the different zones. The direct simulation Monte Carlo (DSMC) method and the Navier-Stokes equations are employed to compute the number densities of the different OH electronically and vibrationally excited states. Different to the previous work, the trace species separation (TSS) algorithm is applied twice in order to accurately calculate the densities of OH species and its excited states. Using a non-equilibrium radiation model, the OH ultraviolet emission spectra and intensity at different altitudes are computed, and good agreement is obtained with the flight measured data.

  16. A Sensitivity Analysis Approach to Identify Key Environmental Performance Factors

    Directory of Open Access Journals (Sweden)

    Xi Yu

    2014-01-01

    Full Text Available Life cycle assessment (LCA is widely used in design phase to reduce the product’s environmental impacts through the whole product life cycle (PLC during the last two decades. The traditional LCA is restricted to assessing the environmental impacts of a product and the results cannot reflect the effects of changes within the life cycle. In order to improve the quality of ecodesign, it is a growing need to develop an approach which can reflect the changes between the design parameters and product’s environmental impacts. A sensitivity analysis approach based on LCA and ecodesign is proposed in this paper. The key environmental performance factors which have significant influence on the products’ environmental impacts can be identified by analyzing the relationship between environmental impacts and the design parameters. Users without much environmental knowledge can use this approach to determine which design parameter should be first considered when (redesigning a product. A printed circuit board (PCB case study is conducted; eight design parameters are chosen to be analyzed by our approach. The result shows that the carbon dioxide emission during the PCB manufacture is highly sensitive to the area of PCB panel.

  17. Systemic Thinking and Requisite Holism in Mastering Logistics Risks: the Model for Identifying Risks in Organisations and Supply Chain

    OpenAIRE

    Borut Jereb; Teodora Ivanuša; Bojan Rosi

    2013-01-01

    Risks in logistic processes represent one of the major issues in supply chain management nowadays. Every organization strives for success, and uninterrupted operations are the key factors in achieving this goal, which cannot be achieved without efficient risk management. In the scope of supply chain risk research, we identified some key issues in the field, the major issue being the lack of standardization and models, which can make risk management in an organization easier and more efficient...

  18. A Case Study of Issues of Strategy Implementation in Internationalization of Higher Education

    Science.gov (United States)

    Jiang, Nan; Carpenter, Victoria

    2013-01-01

    Purpose: The purpose of this research is to identify and critically evaluate key issues faced by an institution in the quest to implement higher education internationalization. Design/methodology/approach: A qualitative research is conducted in a post-1992 UK university. A total of 20 interviewees from three key departments participated in this…

  19. Regulatory policy issues and the Clean Air Act: Issues and papers from the state implementation workshops

    Energy Technology Data Exchange (ETDEWEB)

    Rose, K. [ed.; Burns, R.E.

    1993-07-01

    The National Regulatory Research Institute (NRRI), with funding from the US Environmental Protection Agency (EPA) and the US Department of Energy (DOE), conducted four regional workshops` on state public utility commission implementation of the Clean Air Act Amendments of 1990 (CAAA). The workshops had four objectives: (1) to discuss key issues and concerns on CAAA implementation, (2) to encourage a discussion among states on issues of common interests, (3) to attempt to reach consensus, where possible, on key issues, and (4) to provide the workshop participants with information and materials to assist in developing state rules, orders, and procedures. From the federal perspective, a primary goal was to ensure that workshop participants return to their states with a comprehensive background and understanding of how state commission actions may affect implementation of the CAAA and to be able to provide guidance to their jurisdictional utilities. It was hoped that this would reduce some of the uncertainty utilities face and assist in the development of an efficient allowance market. This report is divided into two main sections. In Section II, eleven principal issues are identified and discussed. These issues were chosen because they were either the most frequently discussed or they were related to the questions asked in response to the speakers` presentations. This section does not cover all the issues relevant to state implementation nor all the issues discussed at the workshops; rather, Section II is intended to provide an overview of the,planning, ratemaking, and multistate issues. Part III is a series of workshop papers presented by some of the speakers. Individual papers have been cataloged separately.

  1. Key Durability Issues with Mullite-Based Environmental Barrier Coatings for Si-Based Ceramics

    Science.gov (United States)

    Lee, Kang N.

    2000-01-01

    Plasma-sprayed mullite (3Al2O3.2SiO2) and mullite/yttria-stabilized-zirconia (YSZ) dual layer coatings have been developed to protect silicon -based ceramics from environmental attack. Mullite-based coating systems show excellent durability in air. However, in combustion environments, corrosive species such as molten salt or water vapor penetrate through cracks in the coating and attack the Si-based ceramics along the interface. Thus the modification of the coating system for enhanced crack-resistance is necessary for long-term durability in combustion environments. Other key durability issues include interfacial contamination and coating/substrate bonding. Interfacial contamination leads to enhanced oxidation and interfacial pore formation, while a weak coating/substrate bonding leads to rapid attack of the interface by corrosive species, both of which can cause a premature failure of the coating. Interfacial contamination can be minimized by limiting impurities in coating and substrate materials. The interface may be modified to improve the coating/substrate bond.

  2. Modified Principal Component Analysis for Identifying Key Environmental Indicators and Application to a Large-Scale Tidal Flat Reclamation

    Directory of Open Access Journals (Sweden)

    Kejian Chu

    2018-01-01

    Full Text Available Identification of the key environmental indicators (KEIs from a large number of environmental variables is important for environmental management in tidal flat reclamation areas. In this study, a modified principal component analysis approach (MPCA has been developed for determining the KEIs. The MPCA accounts for the two important attributes of the environmental variables: pollution status and temporal variation, in addition to the commonly considered numerical divergence attribute. It also incorporates the distance correlation (dCor to replace the Pearson’s correlation to measure the nonlinear interrelationship between the variables. The proposed method was applied to the Tiaozini sand shoal, a large-scale tidal flat reclamation region in China. Five KEIs were identified as dissolved inorganic nitrogen, Cd, petroleum in the water column, Hg, and total organic carbon in the sediment. The identified KEIs were shown to respond well to the biodiversity of phytoplankton. This demonstrated that the identified KEIs adequately represent the environmental condition in the coastal marine system. Therefore, the MPCA is a practicable method for extracting effective indicators that have key roles in the coastal and marine environment.

  3. Ethical issues in animal cloning.

    Science.gov (United States)

    Fiester, Autumn

    2005-01-01

    The issue of human reproductive cloning has recently received a great deal attention in public discourse. Bioethicists, policy makers, and the media have been quick to identify the key ethical issues involved in human reproductive cloning and to argue, almost unanimously, for an international ban on such attempts. Meanwhile, scientists have proceeded with extensive research agendas in the cloning of animals. Despite this research, there has been little public discussion of the ethical issues raised by animal cloning projects. Polling data show that the public is decidedly against the cloning of animals. To understand the public's reaction and fill the void of reasoned debate about the issue, we need to review the possible objections to animal cloning and assess the merits of the anti-animal cloning stance. Some objections to animal cloning (e.g., the impact of cloning on the population of unwanted animals) can be easily addressed, while others (e.g., the health of cloned animals) require more serious attention by the public and policy makers.

  4. Education Studies: Issues & Critical Perspectives

    Science.gov (United States)

    Kassem, Derek; Mufti, Emmanuel; Robinson, John

    2006-01-01

    This major text for Education Studies students provides a critical account of key issues in education today. The text features: (1) A critical analysis of key issues in Education Studies to encourage students' thinking about education in the broadest terms; (2) Themed sections with introductions to link the issues discussed in each chapter; (3)…

  5. Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

    Science.gov (United States)

    Luisier, Raphaëlle; Unterberger, Elif B.; Goodman, Jay I.; Schwarz, Michael; Moggs, Jonathan; Terranova, Rémi; van Nimwegen, Erik

    2014-01-01

    Gene regulatory interactions underlying the early stages of non-genotoxic carcinogenesis are poorly understood. Here, we have identified key candidate regulators of phenobarbital (PB)-mediated mouse liver tumorigenesis, a well-characterized model of non-genotoxic carcinogenesis, by applying a new computational modeling approach to a comprehensive collection of in vivo gene expression studies. We have combined our previously developed motif activity response analysis (MARA), which models gene expression patterns in terms of computationally predicted transcription factor binding sites with singular value decomposition (SVD) of the inferred motif activities, to disentangle the roles that different transcriptional regulators play in specific biological pathways of tumor promotion. Furthermore, transgenic mouse models enabled us to identify which of these regulatory activities was downstream of constitutive androstane receptor and β-catenin signaling, both crucial components of PB-mediated liver tumorigenesis. We propose novel roles for E2F and ZFP161 in PB-mediated hepatocyte proliferation and suggest that PB-mediated suppression of ESR1 activity contributes to the development of a tumor-prone environment. Our study shows that combining MARA with SVD allows for automated identification of independent transcription regulatory programs within a complex in vivo tissue environment and provides novel mechanistic insights into PB-mediated hepatocarcinogenesis. PMID:24464994

  6. Protocol for a thematic synthesis to identify key themes and messages from a palliative care research network.

    LENUS (Irish Health Repository)

    Nicholson, Emma

    2016-10-21

    Research networks that facilitate collaborative research are increasing both regionally and globally and such collaborations contribute greatly to knowledge transfer particularly in health research. The Palliative Care Research Network is an Irish-based network that seeks to create opportunities and engender a collaborative environment to encourage innovative research that is relevant for policy and practice. The current review outlines a methodology to identify cross-cutting messages to identify how dissemination outputs can be optimized to ensure that key messages from this research reaches all knowledge users.

  7. Nuclear Knowledge Management Implementation Issues In Sri Lanka

    International Nuclear Information System (INIS)

    Bandara, H.M.N.R.

    2014-01-01

    About Knowledge Management: Process of organizing and distributing an Organization’s collective wisdom so the right information gets to the right people at the right time. NKM Implementation Problems in Sri Lanka: • Difficulty of identifying nuclear knowledge holders; • NKM has not been given considerable importance; • Many nuclear science experts are in retirement age; • No proper mechanism is available to replace young personnel for their positions; • Unawareness of general public about his technology. • Capacity building through training and education and transferring knowledge from centers of knowledge to centers of growth are key issues. • Development of new courses related to nuclear science is a key issue to be highly considered. • The tendency towards the training and educations of nuclear personnel in the country is becoming less and less

  8. Identifying Issues in Applying Integrated Project Delivery to Domestic Nuclear Power Plant Construction Projects

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Joo [Korean Nuclear Society, Daejeon (Korea, Republic of)

    2016-05-15

    Integrated Project Delivery (IPD) is defined as that people, systems, business structures, and practices of key stakeholders are incorporated into a single-team, with a single process, which executes a project in a way of optimizing the project's outcome, increasing values delivered to the end user, reducing waste, and maximizing efficiency throughout the phases of engineering to construction. The researcher had carried out literature review in terms of IPD to identify major characteristics of IPD which are presented in the following section and had compared such characteristics against peculiarities of nuclear power plant (NPP) construction projects in order to shed light on obstacles in possible application of IPD method to domestic NPP construction projects in the coming days. In this research, three (3) major characteristics of IPD were identified: 1) key stakeholders signing one balanced contract, forming de facto one body, sharing risk and reward 2) an integrated project team being formed in the early stage of a project and providing input to minimize time and cost loss from rework downstream 3) team members co-locating, having open and direct communication, making decisions on time, and pursuing the success of the project itself.

  9. Emerging ICT implementation issues in aged care.

    Science.gov (United States)

    Kapadia, Vasvi; Ariani, Arni; Li, Junhua; Ray, Pradeep K

    2015-11-01

    Demand for aged care services continues to soar as a result of an aging population. This increasing demand requires more residential aged care facilities and healthcare workforce. One recommended solution is to keep older people in their homes longer and support their independent life through the use of information and communication technologies (ICT). However, the aged care sector is still in the early stages of adopting ICT. The aim of this study was to identify the key issues that affect the adoption of ICT in the aged care sector. A systematic literature review was undertaken and involved four steps. The first two steps aimed to identify and select relevant articles. Data was then extracted from the selected articles and identified issues were analyzed and grouped into three major categories. ICT adoption issues were categorized into different perspectives, representing older people, health professionals and management. Our findings showed that all three groups were mostly concerned with issues around behavior, cost and lack of technical skills. Findings reported in this study will help decision makers at aged care settings to systematically understand issues related to ICT adoption and thus proactively introduce interventions to improve use of ICT in this sector. On the basis of our findings, we suggest future research focus on the examination of aged care workflow and assessment of return on ICT investment. Copyright © 2015. Published by Elsevier Ireland Ltd.

  10. Environmental trends and issues at the research horizon

    International Nuclear Information System (INIS)

    Schwartz, J.H.; Warshaw, C.J.; Stoner, B.; Coerr, S.; O'Neal, J.

    1992-01-01

    This report provides a forecast of environmental trends and issues likely to emerge in the next 5 to 15 years. The report identifies and describes eleven significant emerging tends (i.e., general shifts in environmental policy-making, technology, regulation and public opinion) and - specific environmental issues (i.e., real or perceived environmental problems). The report further describes various debates or key questions that will determine over the next 5 to 15 years the potential government response to these environmental issues. This information is intended to assist the Gas research Institute as a research organization in planning and initiating research projects that will be relevant to important debates in the future

  11. Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation.

    Science.gov (United States)

    Goldstein, Cory E; Weijer, Charles; Brehaut, Jamie C; Fergusson, Dean A; Grimshaw, Jeremy M; Horn, Austin R; Taljaard, Monica

    2018-02-27

    Pragmatic randomized controlled trials (RCTs) are designed to evaluate the effectiveness of interventions in real-world clinical conditions. However, these studies raise ethical issues for researchers and regulators. Our objective is to identify a list of key ethical issues in pragmatic RCTs and highlight gaps in the ethics literature. We conducted a scoping review of articles addressing ethical aspects of pragmatic RCTs. After applying the search strategy and eligibility criteria, 36 articles were included and reviewed using content analysis. Our review identified four major themes: 1) the research-practice distinction; 2) the need for consent; 3) elements that must be disclosed in the consent process; and 4) appropriate oversight by research ethics committees. 1) Most authors reject the need for a research-practice distinction in pragmatic RCTs. They argue that the distinction rests on the presumptions that research participation offers patients less benefit and greater risk than clinical practice, but neither is true in the case of pragmatic RCTs. 2) Most authors further conclude that pragmatic RCTs may proceed without informed consent or with simplified consent procedures when risks are low and consent is infeasible. 3) Authors who endorse the need for consent assert that information need only be disclosed when research participation poses incremental risks compared to clinical practice. Authors disagree as to whether randomization must be disclosed. 4) Finally, all authors view regulatory oversight as burdensome and a practical impediment to the conduct of pragmatic RCTs, and argue that oversight procedures ought to be streamlined when risks to participants are low. The current ethical discussion is framed by the assumption that the function of research oversight is to protect participants from risk. As pragmatic RCTs commonly involve usual care interventions, the risks may be minimal. This leads many to reject the research-practice distinction and question

  12. A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

    DEFF Research Database (Denmark)

    Menzel, Tobias; Nähse-Kumpf, Viola; Kousholt, Arne Nedergaard

    2011-01-01

    To identify key connections between DNA-damage repair and checkpoint pathways, we performed RNA interference screens for regulators of the ionizing radiation-induced G2 checkpoint, and we identified the breast cancer gene BRCA2. The checkpoint was also abrogated following depletion of PALB2......, an interaction partner of BRCA2. BRCA2 and PALB2 depletion led to premature checkpoint abrogation and earlier activation of the AURORA A-PLK1 checkpoint-recovery pathway. These results indicate that the breast cancer tumour suppressors and homologous recombination repair proteins BRCA2 and PALB2 are main...

  13. Information processing in bacteria: memory, computation, and statistical physics: a key issues review

    International Nuclear Information System (INIS)

    Lan, Ganhui; Tu, Yuhai

    2016-01-01

    Living systems have to constantly sense their external environment and adjust their internal state in order to survive and reproduce. Biological systems, from as complex as the brain to a single E. coli cell, have to process these data in order to make appropriate decisions. How do biological systems sense external signals? How do they process the information? How do they respond to signals? Through years of intense study by biologists, many key molecular players and their interactions have been identified in different biological machineries that carry out these signaling functions. However, an integrated, quantitative understanding of the whole system is still lacking for most cellular signaling pathways, not to say the more complicated neural circuits. To study signaling processes in biology, the key thing to measure is the input-output relationship. The input is the signal itself, such as chemical concentration, external temperature, light (intensity and frequency), and more complex signals such as the face of a cat. The output can be protein conformational changes and covalent modifications (phosphorylation, methylation, etc), gene expression, cell growth and motility, as well as more complex output such as neuron firing patterns and behaviors of higher animals. Due to the inherent noise in biological systems, the measured input-output dependence is often noisy. These noisy data can be analysed by using powerful tools and concepts from information theory such as mutual information, channel capacity, and the maximum entropy hypothesis. This information theory approach has been successfully used to reveal the underlying correlations between key components of biological networks, to set bounds for network performance, and to understand possible network architecture in generating observed correlations. Although the information theory approach provides a general tool in analysing noisy biological data and may be used to suggest possible network architectures in

  14. Overview of Variable Renewable Energy Regulatory Issues: A Clean Energy Regulators Initiative Report

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.; Cox, S.

    2014-05-01

    This CERI report aims to provide an introductory overview of key regulatory issues associated with the deployment of renewable energy -- particularly variable renewable energy (VRE) sources such wind and solar power. The report draws upon the research and experiences from various international contexts, and identifies key ideas that have emerged from the growing body of VRE deployment experience and regulatory knowledge. The report assumes basic familiarity with regulatory concepts, and although it is not written for a technical audience, directs the reader to further reading when available. VRE deployment generates various regulatory issues: substantive, procedural, and public interest issues, and the report aims to provide an empirical and technical grounding for all three types of questions as appropriate.

  15. Independent assessment is key to financial well-being.

    Science.gov (United States)

    Karling, J; Pyper, T

    1999-02-01

    Both traditional group practices and IPAs have felt the impact of changes brought about by managed care. Group practices need to ensure that their financial reporting and cost-accounting methods capture information that is key to decision making. An independent assessment of financial procedures helps identify any outstanding issues and maintain financial well-being. This assessment should be conducted at least quarterly so that potential problems can be resolved, income opportunities explored, and cost-saving measures adopted in a timely manner.

  16. Key issues in transplant tourism.

    Science.gov (United States)

    Akoh, Jacob A

    2012-02-24

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations.

  17. Materials issues in the design of the ITER first wall, blanket, and divertor

    International Nuclear Information System (INIS)

    Mattas, R.F.; Smith, D.L.; Wu, C.H.; Shatalov, G.

    1992-01-01

    During the ITER conceptual design study, a property data base was assembled, the key issues were identified, and a comprehensive R ampersand D plan was formulated to resolve these issues. The desired properties of candidate ITER divertor, first wall, and blanket materials are briefly reviewed, and the major materials issues are presented. Estimates of the influence of materials properties on the performance limits of the first wall, blanket, and divertor are presented

  18. Postsecondary Students With Psychiatric Disabilities Identify Core Services and Key Ingredients to Supporting Education Goals.

    Science.gov (United States)

    Biebel, Kathleen; Mizrahi, Raphael; Ringeisen, Heather

    2017-10-26

    Accessing and successfully completing postsecondary educational opportunities may be challenging for those living with psychiatric disabilities. This exploratory study highlights the experiences of individuals with psychiatric disabilities participating in postsecondary educational support initiatives. Investigators conducted case studies with 3 education support initiatives across the United States. Focus groups revealed what concrete supported education services were helpful and key ingredients in delivering education supports. Access to specialists, mindfulness techniques, help with time management and procrastination, and facilitating classroom accommodations were identified as critical. Developing authentic relationships with supported education staff, flexibility in service delivery and access to student peers living with psychiatric disabilities were noted as key ingredients in service delivery. Incorporating the voice of students with psychiatric disabilities into supported education services can increase access, involvement, and retention, therein providing more supports to students with psychiatric disabilities achieving their postsecondary education goals. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Key issues for low-cost FGD installations

    Energy Technology Data Exchange (ETDEWEB)

    DePriest, W.; Mazurek, J.M. [Sargent & Lundy LLC, Chicago, IL (United States)

    1995-12-01

    This paper will discuss various methods for installing low-cost FGD systems. The paper will include a discussion of various types of FGD systems available, both wet and dry, and will compare the relative cost of each type. Important design issues, such as use of spare equipment, materials of construction, etc. will be presented. An overview of various low-cost construction techniques (i.e., modularization) will be included. This paper will draw heavily from Sargent & Lundy`s database of past and current FGD projects together with information we gathered for several Electric Power Research Institute (EPRI) studies on the subject.

  20. Environmental issues associated with R Reactor renovation and startup

    International Nuclear Information System (INIS)

    Marter, W.L.

    1982-01-01

    This memorandum identifies the more significant environmental issues that would be associated with renovation and startup of R Reactor to meet future demands for nuclear weapon materials. Some key environmental issues identified are: potential occupational radiation exposures associated with repairing the leaks in the reactor nozzles and thermal shield tanks and with renovating the disassembly basin facilities; the impacts of constructing additional cooling water pumping capacity; the effect of increased pumping on impingement and entrainment at the pump houses; thermal effects on the R Canal-precooler pond-Par Pond ecosystem from increased discharge of cooling water; and effects of increased water flow in Lower Three Runs Creek on biota and on cesium-137 remobilization

  1. Energy investments and environmental implications: key policy issues in developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Siddayao, Corazon M. (World Bank Washington, DC (USA). Economic Development Institute)

    1992-03-15

    Energy investments imply changes in the physical, social, and economic environment. Hence, both the short-term and the long-term costs and benefits of these investments must be taken into account. These changes may affect not only the immediate environment of the investment site but may extend geographically far beyond national borders as well as beyond the lifetimes of the people for whom the investments are intended. This paper reviews the issues relevant to developing countries. General conceptual and policies issues are discussed. Issues about the measurement of costs and benefits (including issues of 'sustainability' and the internalization of externalities resulting from environmental changes) as well as the role of opportunity costs in deciding a country's energy investment strategies are raised. The macroeconomic and institutional issues relevant to environmental impacts that might be incorporated in energy planning are suggested. The paper is based on a presentation to the 'Workshop on energy investments and the environment'. 24 refs., 1 fig.

  2. Identifying sustainability issues using participatory SWOT analysis - A case study of egg production in the Netherlands

    NARCIS (Netherlands)

    Mollenhorst, H.; Boer, de I.J.M.

    2004-01-01

    The aim of this paper was to demonstrate how participatory strengths, weaknesses, opportunities and threats (SWOT) analysis can be used to identify relevant economic, ecological and societal (EES) issues for the assessment of sustainable development. This is illustrated by the case of egg production

  3. Identifying key radiogenomic associations between DCE-MRI and micro-RNA expressions for breast cancer

    Science.gov (United States)

    Samala, Ravi K.; Chan, Heang-Ping; Hadjiiski, Lubomir; Helvie, Mark A.; Kim, Renaid

    2017-03-01

    Understanding the key radiogenomic associations for breast cancer between DCE-MRI and micro-RNA expressions is the foundation for the discovery of radiomic features as biomarkers for assessing tumor progression and prognosis. We conducted a study to analyze the radiogenomic associations for breast cancer using the TCGA-TCIA data set. The core idea that tumor etiology is a function of the behavior of miRNAs is used to build the regression models. The associations based on regression are analyzed for three study outcomes: diagnosis, prognosis, and treatment. The diagnosis group consists of miRNAs associated with clinicopathologic features of breast cancer and significant aberration of expression in breast cancer patients. The prognosis group consists of miRNAs which are closely associated with tumor suppression and regulation of cell proliferation and differentiation. The treatment group consists of miRNAs that contribute significantly to the regulation of metastasis thereby having the potential to be part of therapeutic mechanisms. As a first step, important miRNA expressions were identified and their ability to classify the clinical phenotypes based on the study outcomes was evaluated using the area under the ROC curve (AUC) as a figure-of-merit. The key mapping between the selected miRNAs and radiomic features were determined using least absolute shrinkage and selection operator (LASSO) regression analysis within a two-loop leave-one-out cross-validation strategy. These key associations indicated a number of radiomic features from DCE-MRI to be potential biomarkers for the three study outcomes.

  4. Ethically-based clinical decision-making in physical therapy: process and issues.

    Science.gov (United States)

    Finch, Elspeth; Geddes, E Lynne; Larin, Hélène

    2005-01-01

    The identification and consideration of relevant ethical issues in clinical decision-making, and the education of health care professionals (HCPs) in these skills are key factors in providing quality health care. This qualitative study explores the way in which physical therapists (PTs) integrate ethical issues into clinical practice decisions and identifies ethical themes used by PTs. A purposive sample of eight PTs was asked to describe a recent ethically-based clinical decision. Transcribed interviews were coded and themes identified related to the following categories: 1) the integration of ethical issues in the clinical decision-making process, 2) patient welfare, 3) professional ethos of the PT, and 4) health care economics and business practices. Participants readily described clinical situations involving ethical issues but rarely identified specific conflicting ethical issues in their description. Ethical dilemmas were more frequently resolved when there were fewer emotional sequelae associated with the dilemma, and the PT had a clear understanding of professional ethos, valued patient autonomy, and explored a variety of alternative actions before implementing one. HCP students need to develop a clear professional ethos and an increased understanding of the economic factors that will present ethical issues in practice.

  5. Reforming Agricultural Trade for Developing Countries : Volume 1. Key Issues for a Pro-Development Outcome of the Doha Round

    OpenAIRE

    McCalla, Alex F.; Nash, John

    2007-01-01

    Reforming agricultural trade for developing countries is a two-volume set. The first volume is subtitled Key issues for a pro- development outcome of the Doha Round, and it is focused on specific concerns that are being encountered in the agricultural negotiations, and on strategies for dealing with them to arrive at a final agreement that will significantly spur growth and reduce poverty in developing countries. The companion volume is subtitled Quantifying the impact of multilateral trade r...

  6. Introduction strategies raise key questions.

    Science.gov (United States)

    Finger, W R; Keller, S

    1995-09-01

    Key issues that must be considered before a new contraceptive is introduced center on the need for a trained provider to begin or terminate the method, its side effects, duration of use, method's ability to meet users' needs and preferences, and extra training or staff requirements. Logistics and economic issues to consider are identifying a dependable way of effectively supplying commodities, planning extra services needed for the method, and cost of providing the method. Each contraceptive method presents a different side effect pattern and burdens the service delivery setting differently. The strategy developed to introduce or expand the 3-month injectable Depo-Provera (DMPA) can be used for any method. It includes a needs assessment and addresses regulatory issues, service delivery policies and procedures, information and training, evaluation, and other concerns. Viet Nam's needs assessment showed that Norplant should not be introduced until the service delivery system becomes stronger. Any needs assessment for expansion of contraceptive services should cover sexually transmitted disease/HIV issues. A World Health Organization strategy helps officials identify the best method mix for local situations. Introductory strategies must aim to improve the quality of family planning programs and expand choices. Many begin by examining existing data and conducting interviews with policymakers, users, providers, and women's health advocates. Introductory programs for Norplant focus on provider training, adequate counseling and informed consent for users, and ready access to removal. They need a well-prepared service delivery infrastructure. The first phase of the DMPA introductory strategy for the Philippines comprised a social marketing campaign and DMPA introduction at public clinics in 10 pilot areas with strong service delivery. Successful AIDS prevention programs show that people tend to use barrier methods when they are available. USAID is currently studying

  7. Maquila Workers’ Health: Basic Issues, What is Known, and a Pilot Study in Nicaragua

    Directory of Open Access Journals (Sweden)

    Luis Blanco R.

    2008-09-01

    Full Text Available Occupational health issues identified in maquilas include respiratory, musculoskeletal, psychological problems, and accidents. This study identifies the basic health issues, as well as the sources and investigational methods needed for drafting health standards for maquilas. It sets out conceptual guidelines, suggesting general methodological strategies appropriate for studies of workers’ health and its determinants in the maquiladora sector. The conceptual-methodological model is based on 1 a review of relevant studies, 2 a mixed methods pilot feasibility study within the community of workers and social actors of a textile maquila in Nicaragua, and 3 the conceptual-methodological integration of a literature review with the results of the pilot study. The main issues identified are the organization of work, health, governmental regulation, family and gender, infrastructure and environment. Methodological recommendations focus on the principle of triangulation; the use of anonymous questionnaires and focus groups to examine specific issues; individual interviews with management personnel and members of the community; and the value of family members as key informers on the impact on family, environment and community. Observation of actual work procedures is ideal but not always possible. A joint health and safety committee and a health services unit would be key instruments in the prevention of accidents and illness and in health promotion and care.

  8. Origins of life: a problem for physics, a key issues review

    Science.gov (United States)

    Imari Walker, Sara

    2017-09-01

    The origins of life stands among the great open scientific questions of our time. While a number of proposals exist for possible starting points in the pathway from non-living to living matter, these have so far not achieved states of complexity that are anywhere near that of even the simplest living systems. A key challenge is identifying the properties of living matter that might distinguish living and non-living physical systems such that we might build new life in the lab. This review is geared towards covering major viewpoints on the origin of life for those new to the origin of life field, with a forward look towards considering what it might take for a physical theory that universally explains the phenomenon of life to arise from the seemingly disconnected array of ideas proposed thus far. The hope is that a theory akin to our other theories in fundamental physics might one day emerge to explain the phenomenon of life, and in turn finally permit solving its origins.

  9. Technical Issues Associated With the Use of Intermediate Ethanol Blends (>E10) in the U.S. Legacy Fleet

    Energy Technology Data Exchange (ETDEWEB)

    Rich, Bechtold [Alliance Technical Services; Thomas, John F [ORNL; Huff, Shean P [ORNL; Szybist, James P [ORNL; West, Brian H [ORNL; Theiss, Timothy J [ORNL; Timbario, Tom [Alliance Technical Services; Goodman, Marc [Alliance Technical Services

    2007-08-01

    The Oak Ridge National Laboratory (ORNL) supports the U.S. Department of Energy (DOE) in assessing the impact of using intermediate ethanol blends (E10 to E30) in the legacy fleet of vehicles in the U.S. fleet. The purpose of this report is to: (1) identify the issues associated with intermediate ethanol blends with an emphasis on the end-use or vehicle impacts of increased ethanol levels; (2) assess the likely severity of the issues and whether they will become more severe with higher ethanol blend levels, or identify where the issue is most severe; (3) identify where gaps in knowledge exist and what might be required to fill those knowledge gaps; and (4) compile a current and complete bibliography of key references on intermediate ethanol blends. This effort is chiefly a critical review and assessment of available studies. Subject matter experts (authors and selected expert contacts) were consulted to help with interpretation and assessment. The scope of this report is limited to technical issues. Additional issues associated with consumer, vehicle manufacturer, and regulatory acceptance of ethanol blends greater than E10 are not considered. The key findings from this study are given.

  10. Senior expert symposium on electricity and the environment, Helsinki, Finland, 13-17 May 1991. Key issues papers

    International Nuclear Information System (INIS)

    1991-07-01

    This volume contains the four Key Issues Papers prepared as background papers by international expert groups for the Senior Expert Symposium on Electricity and the Environment held in Helsinki, Finland in May 1991. The papers are on topics selected as the central themes of the symposium: energy and electricity supply and demand - implications for the global environment; energy sources and technologies for electricity generation; comparative environmental and health effects of different energy systems for electricity generation; and the incorporation of environmental and health impacts into policy, planning and decision making for the electricity sector. The four papers have been indexed separately. Refs, figs and tabs

  11. Exploring the effects of spatial autocorrelation when identifying key drivers of wildlife crop-raiding.

    Science.gov (United States)

    Songhurst, Anna; Coulson, Tim

    2014-03-01

    Few universal trends in spatial patterns of wildlife crop-raiding have been found. Variations in wildlife ecology and movements, and human spatial use have been identified as causes of this apparent unpredictability. However, varying spatial patterns of spatial autocorrelation (SA) in human-wildlife conflict (HWC) data could also contribute. We explicitly explore the effects of SA on wildlife crop-raiding data in order to facilitate the design of future HWC studies. We conducted a comparative survey of raided and nonraided fields to determine key drivers of crop-raiding. Data were subsampled at different spatial scales to select independent raiding data points. The model derived from all data was fitted to subsample data sets. Model parameters from these models were compared to determine the effect of SA. Most methods used to account for SA in data attempt to correct for the change in P-values; yet, by subsampling data at broader spatial scales, we identified changes in regression estimates. We consequently advocate reporting both model parameters across a range of spatial scales to help biological interpretation. Patterns of SA vary spatially in our crop-raiding data. Spatial distribution of fields should therefore be considered when choosing the spatial scale for analyses of HWC studies. Robust key drivers of elephant crop-raiding included raiding history of a field and distance of field to a main elephant pathway. Understanding spatial patterns and determining reliable socio-ecological drivers of wildlife crop-raiding is paramount for designing mitigation and land-use planning strategies to reduce HWC. Spatial patterns of HWC are complex, determined by multiple factors acting at more than one scale; therefore, studies need to be designed with an understanding of the effects of SA. Our methods are accessible to a variety of practitioners to assess the effects of SA, thereby improving the reliability of conservation management actions.

  12. Global trade and health: key linkages and future challenges.

    Science.gov (United States)

    Bettcher, D W; Yach, D; Guindon, G E

    2000-01-01

    Globalization of trade, marketing and investment has important implications for public health, both negative and positive. This article considers the implications of the single package of World Trade Organization (WTO) agreements for public health research and policy, focusing on three themes: commodities, intellectual property rights, and health services. The main aims of the analysis are as follows: to identify how trade issues are associated with the transnationalization of health risks and possible benefits; to identify key areas of research; and to suggest policy-relevant advice and interventions on trade and health issues. The next wave of international trade law will need to take more account of global public health issues. However, to become more engaged in global trade debates, the public health community must gain an understanding of the health effects of global trade agreements. It must also ensure that its own facts are correct, so that public health is not blindly used for political ends, such as justifying unwarranted economic protectionism. "Healthy trade" policies, based on firm empirical evidence and designed to improve health status, are an important step towards reaching a more sustainable form of trade liberalization.

  13. Key Issues on Nuclear Energy Non-proliferation in East Asia

    International Nuclear Information System (INIS)

    Hwang, Yong Soo; Whang, Joo Ho; Lee, Un Chul

    2005-01-01

    Energy demand in East Asia casts a significant challenge to sustainable economy development and socio-political stability in the region which has experienced tensions throughout the history. The energy demand in this region has been dramatically increased since the start of reform in PRC. DPRK is another challenge. The current electricity consumption in DPRK is around 10% of that in ROK. If the economy of PRC continuously grows to the level of neighboring states and if the living standard of DPRK reaches that of ROK, the energy and electricity demand in the region will certainly be out of control unless the proper measures are taken into actions from today. The only feasible energy option is the nuclear one. PRC already proclaimed its ambitious plan to deploy more than 30 reactors in the near future. In addition, a couple of the South Eastern Asian states expressed their willingness to introduce nuclear power plants in the future. The increase in the use of nuclear energy is expected to bring up the nuclear renaissance in the region. However, without the proper mechanisms to supply fresh fuels and to manage spent nuclear fuels with full compliance of nuclear energy nonproliferation, the new development will inevitably cause the instability in the region. So far many interesting proposals on nuclear cooperation in East Asia were announced. Unfortunately, none of them works out properly yet, partly because the old proposals were too political. To restart the engine of the nuclear cooperation and nonproliferation in the region, it is necessary to find out what would be the common interests of the region not so much related to politics. In this paper, some key technical issues are addressed for future regional joint studies

  14. Public key infrastructure building trusted applications and web services

    CERN Document Server

    Vacca, John R

    2004-01-01

    OVERVIEW OF PKI TECHNOLOGYPublic Key Infrastructures (PKIs): What Are They?Type of Certificate Authorities (CAS) ServicesPKI StandardsTypes of Vendor and Third-Party CA SystemsProtecting Private KeysCA System AttacksStolen Private Keys: What Can Be Done?Certificate Practice StatementsPKI ReadinessANALYZING AND DESIGNING PUBLIC KEY INFRASTRUCTURESPKI Design IssuesCost Justification and ConsiderationPKI Standards Design IssuesPKI Architectural Design ConsiderationsIMPLEMENTING PKIRequirementsImplementation ScheduleImplementation CostsPKI PerformanceMANAGING PKIRequesting a CertificateObtaining a

  15. Leading change: 1--identifying the issue.

    Science.gov (United States)

    Kerridge, Joanna

    To enable sustainable change, nurses need to take the lead in managing it. Recent national initiatives have emphasised the importance of frontline staff in service improvement. The ability to influence and manage change has been identified as an essential skill for delivering new models of care. This article is the first in a three-part series designed to help nurses at all levels develop the knowledge and skills they will need to initiate and manage change. This article focuses on identifying what needs to be changed and why.

  16. Issues in Developing the IFSP: A Framework for Establishing Family Outcomes.

    Science.gov (United States)

    Beckman, Paula J.; Bristol, Marie M.

    1991-01-01

    This paper identifies four key issues in the implementation of Individualized Family Service Plans (IFSPs) to provide services to young handicapped children as required by Public Law 99-457. These include sensitivity to cultural diversity, family assessment, intrusiveness, and establishing family outcomes. A typology of family outcomes which…

  17. Key issues for determining the exploitable water resources in a Mediterranean river basin.

    Science.gov (United States)

    Pedro-Monzonís, María; Ferrer, Javier; Solera, Abel; Estrela, Teodoro; Paredes-Arquiola, Javier

    2015-01-15

    One of the major difficulties in water planning is to determine the water availability in a water resource system in order to distribute water sustainably. In this paper, we analyze the key issues for determining the exploitable water resources as an indicator of water availability in a Mediterranean river basin. Historically, these territories are characterized by heavily regulated water resources and the extensive use of unconventional resources (desalination and wastewater reuse); hence, emulating the hydrological cycle is not enough. This analysis considers the Jucar River Basin as a case study. We have analyzed the different possible combinations between the streamflow time series, the length of the simulation period and the reliability criteria. As expected, the results show a wide dispersion, proving the great influence of the reliability criteria used for the quantification and localization of the exploitable water resources in the system. Therefore, it is considered risky to provide a single value to represent the water availability in the Jucar water resource system. In this sense, it is necessary that policymakers and stakeholders make a decision about the methodology used to determine the exploitable water resources in a river basin. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. "Business Ethics Everywhere": An Experiential Exercise to Develop Students' Ability to Identify and Respond to Ethical Issues in Business

    Science.gov (United States)

    Baker, Susan D.; Comer, Debra R.

    2012-01-01

    This article introduces an experiential exercise that enhances students' ability to identify ethical issues and to respond to them in ways that consider the relationship between organizational factors and ethical action. Students identify a required number of ethical incidents in their workplaces during a specified period. Students submit a…

  19. On-site Labour Productivity of New Zealand Construction Industry: Key Constraints and Improvement Measures

    Directory of Open Access Journals (Sweden)

    Serdar Durdyev

    2011-09-01

    Full Text Available Productivity is key to the survival and growth of any organisation, industry or nation. Some factors constrain the achievement of the set project objectives in the New Zealand building and construction industry and are responsible for the reported steady decline of productivity and performance. This study aims to identify the key constraints to on-site labour productivity and improvement measures. Using the descriptive survey method, views of some project managers, contractors and subcontractors in New Zealand were canvassed via pilot interviews and questionnaire surveys at the qualitative and quantity data gathering stages, respectively. Multi-attribute technique was used to analyse the quantitative data. Results showed that the key external constraints to on-site labour productivity comprise, in order of decreasing impact, statutory compliance, unforeseen events and wider external dynamics. The internal constraints, which contribute 67 percent of the onsite productivity issues, comprise reworks, level of skill and experience of the workforce, adequacy of method of construction, buildability issues, and inadequate supervision and coordination. . The factors underlying each broad category of external and internal constraints are reported. The relative levels of impact of the identified constraints are expected to guide the project team in addressing the constraints in a cost-effective manner.

  20. Prospects and applications near ferroelectric quantum phase transitions: a key issues review

    Science.gov (United States)

    Chandra, P.; Lonzarich, G. G.; Rowley, S. E.; Scott, J. F.

    2017-11-01

    The emergence of complex and fascinating states of quantum matter in the neighborhood of zero temperature phase transitions suggests that such quantum phenomena should be studied in a variety of settings. Advanced technologies of the future may be fabricated from materials where the cooperative behavior of charge, spin and current can be manipulated at cryogenic temperatures. The progagating lattice dynamics of displacive ferroelectrics make them appealing for the study of quantum critical phenomena that is characterized by both space- and time-dependent quantities. In this key issues article we aim to provide a self-contained overview of ferroelectrics near quantum phase transitions. Unlike most magnetic cases, the ferroelectric quantum critical point can be tuned experimentally to reside at, above or below its upper critical dimension; this feature allows for detailed interplay between experiment and theory using both scaling and self-consistent field models. Empirically the sensitivity of the ferroelectric T c’s to external and to chemical pressure gives practical access to a broad range of temperature behavior over several hundreds of Kelvin. Additional degrees of freedom like charge and spin can be added and characterized systematically. Satellite memories, electrocaloric cooling and low-loss phased-array radar are among possible applications of low-temperature ferroelectrics. We end with open questions for future research that include textured polarization states and unusual forms of superconductivity that remain to be understood theoretically.

  1. Human-automation collaboration in manufacturing: identifying key implementation factors

    OpenAIRE

    Charalambous, George; Fletcher, Sarah; Webb, Philip

    2013-01-01

    Human-automation collaboration refers to the concept of human operators and intelligent automation working together interactively within the same workspace without conventional physical separation. This concept has commanded significant attention in manufacturing because of the potential applications, such as the installation of large sub-assemblies. However, the key human factors relevant to human-automation collaboration have not yet been fully investigated. To maximise effective implement...

  2. The Use of Key Informant Method for Identifying Children with Blindness and Severe Visual Impairment in Developing Countries.

    Science.gov (United States)

    du Toit, Rènée; Courtright, Paul; Lewallen, Susan

    2017-06-01

    An estimated 19 million children are visually impaired; of these, 1.4 million are irreversibly blind. A key challenge is to identify them early in life to benefit maximally from visual rehabilitation, and/or treatment. This aggregative review and structured literature analysis summarizes evidence of what it is about the key informant (KI) approach that works to identify children with blindness or severe visual impairment (B/SVI) in the community (for whom, to what extent, in what circumstances, in what respect, how and why). Peer-reviewed (PubMed, hand search) and grey literature (Google, World Health Organization website, academic theses, direct requests) were included, and methods and criteria used for identification, productivity (number of children referred per KI), accuracy of referrals (positive predictive value, PPV), age of children with B/SVI, KI definition, sex, information about cost and comparisons aggregated. We included 31 documents describing 22 unique KI programs. Mostly KIs identified children with B/SVI in 1-3 weeks, i.e. "campaign mode." In 60%, KIs were community volunteers, others formal health sector workers (FHSW). Around 0.02-1.56 children per KI (median = 0.25) were successfully recruited. PPV ranged from 12 to 66%. In two studies comparing FHSWs and community KIs, the latter were 8 and 10 times more productive. KIs working in campaign mode may provide an effective approach to identifying children with B/SVI in communities. Including identification of ocular problems and/or other impairments has been recommended. Research on factors that influence effectiveness and on whether KIs continue to contribute could inform programs.

  3. 10 key indicators for the environment - Issue 2012

    International Nuclear Information System (INIS)

    2012-06-01

    Ten indicators of the environment are briefly presented, discussed and illustrated by graphs indicating their evolution since the 1990's: air (air pollution in urban environment), biodiversity (number of common bird species), resources (consumption of materials), water (river pollution by phosphates and nitrates), land occupation (soil artificialization), wastes (urban wastes), climate (carbon dioxide emissions), economy (jobs in the environmental sector), energy (share of renewable energies), and opinion (level of concern of French people regarding the different issues related to environment degradation)

  4. Response to Key Issues Raised in the Post-14 Mathematics Inquiry

    Science.gov (United States)

    Burghes, David; Hindle, Mike

    2004-01-01

    This article is a detailed response to the issues raised by the Post-14 Mathematics Inquiry in the UK. It aims to debate some of the central issues in mathematics teaching in the UK, including recruitment and retention of mathematics teachers, the curriculum content, national assessment, teaching resources (including ICT) and national strategies…

  5. Identifying Determinants of Organizational Development as the Key Developers of Employee Soft Skill

    Directory of Open Access Journals (Sweden)

    Shahjahan Laghari

    2016-10-01

    Full Text Available The purpose of this article is to identify the determinants of organizational development as the key developers of employee soft skills. Various studies have been taken where determinants of organizational development defining soft skills in employees are discussed. However, the current study is different in Pakistani industry context as the link was missing about the determinants of organizational development which in synchronized way help in developing soft skills in employees of firm. This research uses explanatory approach; incorporating secondary data extracted under the light of existing school of thoughts paired with quantification through data collected from respondents in Pakistani corporate sector. Hypotheses are tested using structural equation model (SEM technique. Results This research showed an affirmative link between determinants of organizational development and development of soft skills in employees. Finally, the study proposes enriching insights on few missing links that can be researched and triggered achieving maximized outcomes.

  6. ITER - TVPS remote handling critical design issues

    International Nuclear Information System (INIS)

    1990-09-01

    This report describes critical design issues concerning remote maintenance of the ITER Torus Vacuum Pumping System (TVPS). The key issues under investigation are the regeneration/isolation valve seal and seal mechanism replacement; impact of inert gas operation; impact of remote handling (RH) on the building configuration and RH equipment requirements. Seal exchange concepts are developed and their impact on the valve design identified. Concerns regarding the design and operation of RH equipment in an inert gas atmosphere are also explored. The report compares preliminary RH equipment options, pumping equipment maintenance frequency and their impact on the building design, and makes recommendations where a conflict exists between pumping equipment and the building layout. (51 figs., 11 refs.)

  7. A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways

    International Nuclear Information System (INIS)

    Furuya, Shinji; Chappell, Grace A.; Iwata, Yasuhiro; Uehara, Takeki; Kato, Yuki; Kono, Hiroshi; Bataller, Ramon; Rusyn, Ivan

    2016-01-01

    Clinical data strongly indicate that acute kidney injury (AKI) is a critical complication in alcoholic hepatitis, an acute-on-chronic form of liver failure in patients with advanced alcoholic fibrosis. Development of targeted therapies for AKI in this setting is hampered by the lack of an animal model. To enable research into molecular drivers and novel therapies for fibrosis- and alcohol-associated AKI, we aimed to combine carbon tetrachloride (CCl 4 )-induced fibrosis with chronic intra-gastric alcohol feeding. Male C57BL/6J mice were administered a low dose of CCl 4 (0.2 ml/kg 2 × week/6 weeks) followed by alcohol intragastrically (up to 25 g/kg/day for 3 weeks) and with continued CCl 4 . We observed that combined treatment with CCl 4 and alcohol resulted in severe liver injury, more pronounced than using each treatment alone. Importantly, severe kidney injury was evident only in the combined treatment group. This mouse model reproduced distinct pathological features consistent with AKI in human alcoholic hepatitis. Transcriptomic analysis of kidneys revealed profound effects in the combined treatment group, with enrichment for damage-associated pathways, such as apoptosis, inflammation, immune-response and hypoxia. Interestingly, Havcr1 and Lcn2, biomarkers of AKI, were markedly up-regulated. Overall, this study established a novel mouse model of fibrosis- and alcohol-associated AKI and identified key mechanistic pathways. - Highlights: • Acute kidney injury (AKI) is a critical complication in alcoholic hepatitis • We developed a novel mouse model of fibrosis- and alcohol-associated AKI • This model reproduces key molecular and pathological features of human AKI • This animal model can help identify new targeted therapies for alcoholic hepatitis

  8. The Future We Want: Key Issues on Sustainable Development in Higher Education after Rio and the UN Decade of Education for Sustainable Development

    Science.gov (United States)

    Leal Filho, Walter; Manolas, Evangelos; Pace, Paul

    2015-01-01

    Purpose: This paper aims to provide a description of the achievements of the United Nations (UN) Decade of Education for Sustainable Development (2005-2014) with a focus on higher education, and it describes some of the key issues which will guide sustainable development in the coming years. Design/methodology/approach: The paper initially…

  9. Identifying key drivers of greenhouse gas emissions from biomass feedstocks for energy production

    International Nuclear Information System (INIS)

    Johnson, David R.; Curtright, Aimee E.; Willis, Henry H.

    2013-01-01

    Highlights: • Production emissions dominate transportation and processing emissions. • Choice of feedstock, geographic location and prior land use drive emissions profile. • Within scenarios, emissions variability is driven by uncertainty in yields. • Favorable scenarios maximize carbon storage from direct land-use change. • Similarly, biomass production should attempt to minimize indirect land-use change. -- Abstract: Many policies in the United States, at both the federal and state levels, encourage the adoption of renewable energy from biomass. Though largely motivated by a desire to reduce greenhouse gas emissions, these policies do not explicitly identify scenarios in which the use of biomass will produce the greatest benefits. We have modeled “farm-to-hopper” emissions associated with seven biomass feedstocks, under a wide variety of scenarios and production choices, to characterize the uncertainty in emissions. We demonstrate that only a handful of factors have a significant impact on life cycle emissions: choice of feedstock, geographic location, prior land use, and time dynamics. Within a given production scenario, the remaining variability in emissions is driven by uncertainty in feedstock yields and the release rate of N 2 O into the atmosphere from nitrogen fertilizers. With few exceptions, transport and processing choices have relatively little impact on total emissions. These results illustrate the key decisions that will determine the success of biomass programs in reducing the emissions profile of energy production, and our publicly available model provides a useful tool for identifying the most beneficial production scenarios. While model data and results are restricted to biomass production in the contiguous United States, we provide qualitative guidance for identifying favorable production scenarios that should be applicable in other regions

  10. Knowledge management - A key issue for EnBW

    International Nuclear Information System (INIS)

    Zimmer, H.J.

    2007-01-01

    Full text: The motivation for knowledge management can be summarised with the words of EnBW CEO Prof. Claassen, 2002 'knowledge manager of the year' in Germany: 'Against the backdrop of the ever-increasing complexity of strategic planning and activities on the operational front, knowledge management is a key factor in the long-term success of our business.' Professional knowledge management motivates and supports employees, helping to create networks in which they can lay the foundations for the future success of the company. It must be emphasised that knowledge management is the responsibility of management, and EnBW has established a suitable framework consisting of different action levels and goals: 1) Normative level (corporate culture): creating a knowledge-aware and knowledge-friendly corporate culture 2) Strategic level (human resources): systematic gearing of internal intangible potentials towards future requirements. 3) Operational level (information/communication): making the required knowledge available in the necessary scope and quality, in the right place and at the right time. If knowledge management can generally be seen as basic requirement for successful companies, then it is even more important for nuclear operators. Today, nuclear energy is an important generating technology in Europe, for Germany and for EnBW with major future potential, but a technology that must be employed with great caution and attaching top priority to safe operation. For nuclear operators, the rule is always 'safety first'. But knowledge management implemented and used in the right way can also enhance both safety and competitive operation of the plants at the same time. In this connection, successful knowledge management plays a key role due to the complex interplay of many different disciplines within a demanding legal and regulatory framework, the paramount importance of collective past experience and the high demands on the expertise of the employees operating nuclear

  11. Identifying Key Performance Indicators for Holistic Hospital Management with a Modified DEMATEL Approach.

    Science.gov (United States)

    Si, Sheng-Li; You, Xiao-Yue; Liu, Hu-Chen; Huang, Jia

    2017-08-19

    Performance analysis is an important way for hospitals to achieve higher efficiency and effectiveness in providing services to their customers. The performance of the healthcare system can be measured by many indicators, but it is difficult to improve them simultaneously due to the limited resources. A feasible way is to identify the central and influential indicators to improve healthcare performance in a stepwise manner. In this paper, we propose a hybrid multiple criteria decision making (MCDM) approach to identify key performance indicators (KPIs) for holistic hospital management. First, through integrating evidential reasoning approach and interval 2-tuple linguistic variables, various assessments of performance indicators provided by healthcare experts are modeled. Then, the decision making trial and evaluation laboratory (DEMATEL) technique is adopted to build an interactive network and visualize the causal relationships between the performance indicators. Finally, an empirical case study is provided to demonstrate the proposed approach for improving the efficiency of healthcare management. The results show that "accidents/adverse events", "nosocomial infection", ''incidents/errors", "number of operations/procedures" are significant influential indicators. Also, the indicators of "length of stay", "bed occupancy" and "financial measures" play important roles in performance evaluation of the healthcare organization. The proposed decision making approach could be considered as a reference for healthcare administrators to enhance the performance of their healthcare institutions.

  12. A secure key agreement protocol based on chaotic maps

    International Nuclear Information System (INIS)

    Wang Xing-Yuan; Luan Da-Peng

    2013-01-01

    To guarantee the security of communication in the public channel, many key agreement protocols have been proposed. Recently, Gong et al. proposed a key agreement protocol based on chaotic maps with password sharing. In this paper, Gong et al.'s protocol is analyzed, and we find that this protocol exhibits key management issues and potential security problems. Furthermore, the paper presents a new key agreement protocol based on enhanced Chebyshev polynomials to overcome these problems. Through our analysis, our key agreement protocol not only provides mutual authentication and the ability to resist a variety of common attacks, but also solve the problems of key management and security issues existing in Gong et al.'s protocol

  13. Compact toroid theory issues and approaches: a panel report

    International Nuclear Information System (INIS)

    1985-06-01

    In the six years since the initiation of the compact toroid program by the Office of Fusion Energy, remarkable scientific advances have occurred on both field-reversed configurations (FRC) and spheromaks. This progress has been stimulated by a diverse experimental program with facilities at six laboratories, and by a small but nevertheless broad theoretical research effort encompassing more than a dozen institutions. The close coupling between theoretical and experimental programs has contributed immeasurably to this progress. This document offers guidance for future compact toroid theory by identifying and discussing the key physics issues. In most cases promising approaches to these issues are offered

  14. Exploring work-related issues on corporate sustainability.

    Science.gov (United States)

    Brunoro, C M; Bolis, I; Sznelwar, L I

    2015-01-01

    In a research project about work-related issues and corporate sustainability conducted in Brazil, the goal was to better understand how work-related issues were addressed in the corporate context. Particularly, there are some specific initiatives that serve as guides to organizational decisions, which make their performance indicators for the context of corporate sustainability. 1) To explore the presence of work-related issues and their origins in corporate sustainability approach, analyzing a) corporate disclosures; b) sustainability guidelines that are identified as relevant in corporate disclosures; c) documents that are related to sustainable development and also identified as key-documents for these guidelines and initiatives. 2) To present the activity-centered ergonomics and psychodynamics of work contributions to work-related issues in a corporate sustainability approach. An exploratory study based on multiple sources of evidence that were performed from 2012 to 2013, including interviews with companies that engaged in corporate sustainability and document analysis using the content analysis approach. Work-related issues have been presented since the earliest sustainable development documents. It is feasible to construct an empirical framework for work-related issues and corporate sustainability approaches. 1) Although some authors argue that corporate sustainability has its roots based only on the environmental dimension, there is strong empirical evidence showing that social dimension aspects such as work-related issues have been present since the beginning. 2) Some indicators should be redesigned to more precisely translate the reality of some workplaces, particularly those indicators related to organizational design and mental health.

  15. Identifying and Supporting English Learner Students with Learning Disabilities: Key Issues in the Literature and State Practice. REL 2015-086

    Science.gov (United States)

    Burr, Elizabeth; Haas, Eric; Ferriere, Karen

    2015-01-01

    While the literature on learning disabilities and on second-language acquisition is relatively extensive within the field of education, less is known about the specific characteristics and representation of English learner students with learning disabilities. Because there are no definitive resources and processes for identifying and determining…

  16. The Work/Family Challenge: A Key Career Development Issue.

    Science.gov (United States)

    Kahnweiler, William M; Kahnweiler, Jennifer B.

    1992-01-01

    A few corporations are responding to the impact of family structural changes on workers' ability to balance their roles with flexible benefits and schedules and with training. Work/family issues are an integral part of career and life decision making and must be incorporated into the career development process. (SK)

  17. Key Nuclear Verification Priorities: Safeguards and Beyond

    International Nuclear Information System (INIS)

    Carlson, J.

    2010-01-01

    In addressing nuclear verification priorities, we should look beyond the current safeguards system. Non-proliferation, which the safeguards system underpins, is not an end in itself, but an essential condition for achieving and maintaining nuclear disarmament. Effective safeguards are essential for advancing disarmament, and safeguards issues, approaches and techniques are directly relevant to the development of future verification missions. The extent to which safeguards challenges are successfully addressed - or otherwise - will impact not only on confidence in the safeguards system, but on the effectiveness of, and confidence in, disarmament verification. To identify the key nuclear verification priorities, we need to consider the objectives of verification, and the challenges to achieving these. The strategic objective of IAEA safeguards might be expressed as: To support the global nuclear non-proliferation regime by: - Providing credible assurance that states are honouring their safeguards commitments - thereby removing a potential motivation to proliferate; and - Early detection of misuse of nuclear material and technology - thereby deterring proliferation by the risk of early detection, enabling timely intervention by the international community. Or to summarise - confidence-building, detection capability, and deterrence. These will also be essential objectives for future verification missions. The challenges to achieving these involve a mix of political, technical and institutional dimensions. Confidence is largely a political matter, reflecting the qualitative judgment of governments. Clearly assessments of detection capability and deterrence have a major impact on confidence. Detection capability is largely thought of as 'technical', but also involves issues of legal authority, as well as institutional issues. Deterrence has both political and institutional aspects - including judgments on risk of detection and risk of enforcement action being taken. The

  18. Key Nuclear Verification Priorities - Safeguards and Beyond

    International Nuclear Information System (INIS)

    Carlson, J.

    2010-01-01

    In addressing nuclear verification priorities, we should look beyond the current safeguards system. Non-proliferation, which the safeguards system underpins, is not an end in itself, but an essential condition for achieving and maintaining nuclear disarmament. Effective safeguards are essential for advancing disarmament, and safeguards issues, approaches and techniques are directly relevant to the development of future verification missions. The extent to which safeguards challenges are successfully addressed - or otherwise - will impact not only on confidence in the safeguards system, but on the effectiveness of, and confidence in, disarmament verification. To identify the key nuclear verification priorities, we need to consider the objectives of verification, and the challenges to achieving these. The strategic objective of IAEA safeguards might be expressed as: To support the global nuclear non-proliferation regime by: - Providing credible assurance that states are honouring their safeguards commitments - thereby removing a potential motivation to proliferate; and - Early detection of misuse of nuclear material and technology - thereby deterring proliferation by the risk of early detection, enabling timely intervention by the international community. Or to summarise - confidence-building, detection capability, and deterrence. These will also be essential objectives for future verification missions. The challenges to achieving these involve a mix of political, technical and institutional dimensions. Confidence is largely a political matter, reflecting the qualitative judgment of governments. Clearly assessments of detection capability and deterrence have a major impact on confidence. Detection capability is largely thought of as 'technical', but also involves issues of legal authority, as well as institutional issues. Deterrence has both political and institutional aspects - including judgments on risk of detection and risk of enforcement action being taken. The

  19. The key issues facing the electricity systems of developing countries

    International Nuclear Information System (INIS)

    Oliveira, A. de

    1991-01-01

    This report covers a common project designed to investigate the major issues and possible future direction in the electricity systems of developing countries in AFRICA, ASIA and LATIN AMERICA. Individual centres each had responsibility for preparing a detailed report on the experiences and issues in their own country plus a regional report, in less detail, to cover neighbouring countries. In this disaggregated way, a picture of the whole of the developing world (with the exception of the Middle East, the problems of which are in some ways distinct from those of other developing countries) has been built up. 30 Refs.; 14 Figs.; 33 Tabs

  20. Mass Market Demand Response and Variable Generation Integration Issues: A Scoping Study

    Energy Technology Data Exchange (ETDEWEB)

    Cappers, Peter; Mills, Andrew; Goldman, Charles; Wiser, Ryan; Eto, Joseph H.

    2011-09-10

    This scoping study focuses on the policy issues inherent in the claims made by some Smart Grid proponents that the demand response potential of mass market customers which is enabled by widespread implementation of Advanced Metering Infrastructure (AMI) through the Smart Grid could be the “silver bullet” for mitigating variable generation integration issues. In terms of approach, we will: identify key issues associated with integrating large amounts of variable generation into the bulk power system; identify demand response opportunities made more readily available to mass market customers through widespread deployment of AMI systems and how they can affect the bulk power system; assess the extent to which these mass market Demand Response (DR) opportunities can mitigate Variable Generation (VG) integration issues in the near-term and what electricity market structures and regulatory practices could be changed to further expand the ability for DR to mitigate VG integration issues over the long term; and provide a qualitative comparison of DR and other approaches to mitigate VG integration issues.

  1. Key issues in life cycle assessment of ethanol production from lignocellulosic biomass: Challenges and perspectives.

    Science.gov (United States)

    Singh, Anoop; Pant, Deepak; Korres, Nicholas E; Nizami, Abdul-Sattar; Prasad, Shiv; Murphy, Jerry D

    2010-07-01

    Progressive depletion of conventional fossil fuels with increasing energy consumption and greenhouse gas (GHG) emissions have led to a move towards renewable and sustainable energy sources. Lignocellulosic biomass is available in massive quantities and provides enormous potential for bioethanol production. However, to ascertain optimal biofuel strategies, it is necessary to take into account environmental impacts from cradle to grave. Life cycle assessment (LCA) techniques allow detailed analysis of material and energy fluxes on regional and global scales. This includes indirect inputs to the production process and associated wastes and emissions, and the downstream fate of products in the future. At the same time if not used properly, LCA can lead to incorrect and inappropriate actions on the part of industry and/or policy makers. This paper aims to list key issues for quantifying the use of resources and releases to the environment associated with the entire life cycle of lignocellulosic bioethanol production. Copyright 2009 Elsevier Ltd. All rights reserved.

  2. Implementation Issues for Departure Planning Systems

    Science.gov (United States)

    Hansman, R. John; Feron, Eric; Clarke, John-Paul; Odoni, Amedeo

    1999-01-01

    The objective of the proposed effort is to investigate issues associated with the design and implementation of decision aiding tools to assist in improving the departure process at congested airports. This effort follows a preliminary investigation of potential Departure Planning approaches and strategies, which identified potential benefits in departure efficiency, and also in reducing the environmental impact of aircraft in the departure queue. The preliminary study bas based, in large part, on observations and analysis of departure processes at Boston, Logan airport. The objective of this follow-on effort is to address key implementation issues and to expand the observational base to include airports with different constraints and traffic demand. Specifically, the objectives of this research are to: (1) Expand the observational base to include airports with different underlying operational dynamics. (2) Develop prototype decision aiding algorithms/approaches and assess potential benefits. and (3) Investigate Human Machine Integration (HMI) issues associated with decision aids in tower environments.

  3. GuiaTreeKey, a multi-access electronic key to identify tree genera in French Guiana

    OpenAIRE

    Brousseau, Louise; Baraloto, Christopher

    2016-01-01

    The tropical rainforest of Amazonia is one of the most species-rich ecosystems on earth, with an estimated 16000 tree species. Due to this high diversity, botanical identification of trees in the Amazon is difficult, even to genus, often requiring the assistance of parataxonomists or taxonomic specialists. Advances in informatics tools offer a promising opportunity to develop user-friendly electronic keys to improve Amazonian tree identification. Here, we introduce an original mult...

  4. The Development of Resources of Students in Adolescence as a Key Issue in Contemporary Education

    Directory of Open Access Journals (Sweden)

    Gosk Urszula

    2015-08-01

    Full Text Available In the presented paper, the issue of recognition and building of resources in adolescent pupils was discussed, referring to salutogenic concept of A. Antonovsky and Conservation of Resources Theory of S. E. Hobfoll. Coming out from developmental pedagogy and positive orientation in social sciences, benefits of scientific and educational actions concentrated on identifying pupils’ resources and supporting them in generating them, were shown. On the basis of Polish and foreign literature, empirical research treating about pupils’ resource, was analyzed, with special attention put to the sense of coherence and its components, stress management and behavior fostering health.

  5. Risk management of key issues of FPSO

    Science.gov (United States)

    Sun, Liping; Sun, Hai

    2012-12-01

    Risk analysis of key systems have become a growing topic late of because of the development of offshore structures. Equipment failures of offloading system and fire accidents were analyzed based on the floating production, storage and offloading (FPSO) features. Fault tree analysis (FTA), and failure modes and effects analysis (FMEA) methods were examined based on information already researched on modules of relex reliability studio (RRS). Equipment failures were also analyzed qualitatively by establishing a fault tree and Boolean structure function based on the shortage of failure cases, statistical data, and risk control measures examined. Failure modes of fire accident were classified according to the different areas of fire occurrences during the FMEA process, using risk priority number (RPN) methods to evaluate their severity rank. The qualitative analysis of FTA gave the basic insight of forming the failure modes of FPSO offloading, and the fire FMEA gave the priorities and suggested processes. The research has practical importance for the security analysis problems of FPSO.

  6. Key Management in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ismail Mansour

    2015-09-01

    Full Text Available Wireless sensor networks are a challenging field of research when it comes to security issues. Using low cost sensor nodes with limited resources makes it difficult for cryptographic algorithms to function without impacting energy consumption and latency. In this paper, we focus on key management issues in multi-hop wireless sensor networks. These networks are easy to attack due to the open nature of the wireless medium. Intruders could try to penetrate the network, capture nodes or take control over particular nodes. In this context, it is important to revoke and renew keys that might be learned by malicious nodes. We propose several secure protocols for key revocation and key renewal based on symmetric encryption and elliptic curve cryptography. All protocols are secure, but have different security levels. Each proposed protocol is formally proven and analyzed using Scyther, an automatic verification tool for cryptographic protocols. For efficiency comparison sake, we implemented all protocols on real testbeds using TelosB motes and discussed their performances.

  7. Key challenges to expanding renewable energy

    International Nuclear Information System (INIS)

    Stram, Bruce N.

    2016-01-01

    The key advantage of renewables is that they are free of direct pollution and carbon emissions. Given concern over global warming caused by carbon emissions, there are substantial policy efforts to increase renewable penetrations. The purpose of this paper is to outline and evaluate the challenges presented by increasing penetrations of renewable electricity generation. These generation sources primarily include solar and wind which are growing rapidly and are new enough to the grid that the impact of high penetrations is not fully understood. The intrinsic nature of solar and wind power is very likely to present greater system challenges than “conventional” sources. Within limits, those challenges can be overcome, but at a cost. Later sections of the paper will draw on a variety of sources to identify a range of such costs, at least as they are foreseen by researchers helping prepare ambitious plans for grids to obtain high shares (30–50%) of their megawatt hours from primarily solar and wind generation. Energy poverty issues are outlined and related to renewable costs issues. - Highlights: •Integration of intermittent renewables with existing power grids. •Renewable ramping and over production issues. •Renewable caused system costs. •Energy poverty circumstances and consequences.

  8. A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways

    Energy Technology Data Exchange (ETDEWEB)

    Furuya, Shinji; Chappell, Grace A.; Iwata, Yasuhiro [Department of Veterinary Integrative Biosciences, Texas A& M University, College Station, TX (United States); Uehara, Takeki; Kato, Yuki [Laboratory of Veterinary Pathology, Osaka Prefecture University, Osaka (Japan); Kono, Hiroshi [First Department of Surgery, University of Yamanashi, Yamanashi (Japan); Bataller, Ramon [Division of Gastroenterology & Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, NC (United States); Rusyn, Ivan, E-mail: irusyn@tamu.edu [Department of Veterinary Integrative Biosciences, Texas A& M University, College Station, TX (United States)

    2016-11-01

    Clinical data strongly indicate that acute kidney injury (AKI) is a critical complication in alcoholic hepatitis, an acute-on-chronic form of liver failure in patients with advanced alcoholic fibrosis. Development of targeted therapies for AKI in this setting is hampered by the lack of an animal model. To enable research into molecular drivers and novel therapies for fibrosis- and alcohol-associated AKI, we aimed to combine carbon tetrachloride (CCl{sub 4})-induced fibrosis with chronic intra-gastric alcohol feeding. Male C57BL/6J mice were administered a low dose of CCl{sub 4} (0.2 ml/kg 2 × week/6 weeks) followed by alcohol intragastrically (up to 25 g/kg/day for 3 weeks) and with continued CCl{sub 4}. We observed that combined treatment with CCl{sub 4} and alcohol resulted in severe liver injury, more pronounced than using each treatment alone. Importantly, severe kidney injury was evident only in the combined treatment group. This mouse model reproduced distinct pathological features consistent with AKI in human alcoholic hepatitis. Transcriptomic analysis of kidneys revealed profound effects in the combined treatment group, with enrichment for damage-associated pathways, such as apoptosis, inflammation, immune-response and hypoxia. Interestingly, Havcr1 and Lcn2, biomarkers of AKI, were markedly up-regulated. Overall, this study established a novel mouse model of fibrosis- and alcohol-associated AKI and identified key mechanistic pathways. - Highlights: • Acute kidney injury (AKI) is a critical complication in alcoholic hepatitis • We developed a novel mouse model of fibrosis- and alcohol-associated AKI • This model reproduces key molecular and pathological features of human AKI • This animal model can help identify new targeted therapies for alcoholic hepatitis.

  9. Key Issues in the Application of Knowledge Management in Education

    National Research Council Canada - National Science Library

    Mendoza, George A

    2005-01-01

    .... This shift in paradigms has made knowledge the key resource as organizations shift their focus from natural resources to intellectual assets, heralding the use of a concept called Knowledge Management (KM...

  10. Advancing Understanding on Industrial Relations in Multinational Companies: Key Research Challenges and the INTREPID Contribution

    DEFF Research Database (Denmark)

    Gunnigle, Patrick; Valeria, Pulignano; Edwards, Tony

    2015-01-01

    companies using INTREPID (Investigation of Transnationals’ Employment Practices: an International Database) data. Finally, the paper identifies some of the main industrial relations issues that remain to be addressed, in effect charting a form of research agenda for future work using the INTREPID data......This paper has three principal aims. It firstly provides some theoretical background on the key current research issues and challenges in regard to industrial relations in multinational companies. It then presents a concise review of scholarship to date on industrial relations in multinational...

  11. Key issues in the prevention of obesity.

    Science.gov (United States)

    Gill, T P

    1997-01-01

    Obesity is a serious, chronic medical condition which is associated with a wide range of debilitating and life-threatening conditions. It imposes huge financial burdens on health care systems and the community at large. Obesity develops over time and once it has done so, is difficult to treat. Therefore, the prevention of weight gain offers the only truly effective means of controlling obesity. Very little research has directly addressed the issue of obesity prevention and previous efforts to prevent obesity amongst individuals, groups or whole communities have had very limited success. However, we have learned sufficient from past preventive activities to realise that the management of obesity will require a comprehensive range of strategies with actions that target those with existing weight problems, those at high risk of developing obesity as well as the community as a whole. The prevention and management of obesity in children should be considered a priority as there is a high risk of persistence into adulthood.

  12. Simple Web-based interactive key development software (WEBiKEY) and an example key for Kuruna (Poaceae: Bambusoideae).

    Science.gov (United States)

    Attigala, Lakshmi; De Silva, Nuwan I; Clark, Lynn G

    2016-04-01

    Programs that are user-friendly and freely available for developing Web-based interactive keys are scarce and most of the well-structured applications are relatively expensive. WEBiKEY was developed to enable researchers to easily develop their own Web-based interactive keys with fewer resources. A Web-based multiaccess identification tool (WEBiKEY) was developed that uses freely available Microsoft ASP.NET technologies and an SQL Server database for Windows-based hosting environments. WEBiKEY was tested for its usability with a sample data set, the temperate woody bamboo genus Kuruna (Poaceae). WEBiKEY is freely available to the public and can be used to develop Web-based interactive keys for any group of species. The interactive key we developed for Kuruna using WEBiKEY enables users to visually inspect characteristics of Kuruna and identify an unknown specimen as one of seven possible species in the genus.

  13. Identifying Key Stakeholders in Blended Tertiary Environments: Experts' Perspectives

    Science.gov (United States)

    Tuapawa, Kimberley

    2017-01-01

    Although key stakeholders in blended tertiary environments (BTEs) fulfil an extraordinary role in higher education, significant gaps in knowledge about their identities may be impeding the provision of stakeholder support, limiting their ability to promote effective learning and teaching. As online growth intensifies, it is critical that tertiary…

  14. Key Criteria of "Good Practice" for Constructive Diaspora Engagement in Peacebuilding

    OpenAIRE

    Sinatti, Giulia

    2010-01-01

    textabstractThis discussion paper focuses on the engagement of diasporas in peacebuilding processes in their countries of origin. The main argument put forward in this paper is that, given certain conditions, diasporas carry a potential to fruitfully engage in the field of peacebuilding. After substantiating this claim with a critical discussion of literature and research insight, the issue is further addressed by identifying and collating a set of key criteria of “good practice” for construc...

  15. A Simple Key for Identifying the Sibling Species of the Malaria Vector Anopheles gambiae (Giles Complex by Polytene Chromosome Cytogenetics

    Directory of Open Access Journals (Sweden)

    Music Temitope OBEMBE

    2018-03-01

    Full Text Available It has been established that Anopheles gambiae complex sibling species are the major Plasmodium malaria vectors in Africa; however, not all the sibling species transmit the infection. Easier molecular methods, PCR-based assays, have been developed to distinguish the several members of the A. gambiae complex. However, malaria vector research in less developed countries, particularly sub-Saharan Africa, is being hampered by the lack of PCR facilities in laboratories and the cost of carrying out the assay within lack of funding. Hence, the present study was designed to develop a simple identification key, based on an affordable method of polytene chromosome cytotaxonomy, for identifying the major P. falciparum vectors. The Identification Key was successfully used to identify two members of the A. gambiae complex, A. gambiae sensu stricto and A. arabiensis, which are the most potent malaria vectors in Africa; even so, it could not be used to establish the infective and the refractory strains.

  16. Key Issue

    Directory of Open Access Journals (Sweden)

    Oya Y Rieger

    2012-03-01

    Full Text Available A few months ago, while I was participating in a conference about open access infrastructures, a delegate from a governmental agency asked, “Why does each library need to maintain a repository for their own scientists?” He was rightfully wondering if a broad collaboration in building a network of archives will provide a durable and extensible technology and service framework for ever-increasing digital scholarly content. The ensuing discussion did not offer a plausible response but accentuated that we do not have in place a plan for building an expandable infrastructure to facilitate communication and exchange of information among rapidly proliferating distinct instances of institutional and subject repositories.

  17. Lessons learned in communicating nuclear transportation issues - a case study

    International Nuclear Information System (INIS)

    Reilly, B.; Austin, P.

    1992-01-01

    Successful communication requires several key elements. They include a non-intimidating forum for exchanging information, two-way communication, advance preparation to identify what each party wants to learn, and feedback. There is no single approach that guarantees success. Factors such as technical complexity of the issue, level of support by the public, and trust and confidence among the parties all play a role in determining the most workable approach for any particular situation. This paper illustrates lessons learned by the US Department of Energy (DOE) in communicating nuclear waste disposal and transportation issues to the public

  18. The economics of biomedical waste irradiation: key issues influencing total cost

    International Nuclear Information System (INIS)

    Wilson, B.K.

    1993-01-01

    Each application of gamma irradiation technology is different in one or more significant respects. Disinfection of biomedical wastes presents similar technical challenges to sterilization of medical supplies, but the economic issues are dramatically different. Regulatory requirements, site and technology approvals, waste separation/mixing, transportation, irradiator utilization, economies of scale, and end-product disposal can each have a prohibitive or enabling effect on whether irradiation of biomedical wastes makes good financial sense in a particular situation. This paper discusses each of these issues. (author)

  19. Photovoltaics for Buildings: Key Issues in Pursuit of Market Readiness

    International Nuclear Information System (INIS)

    Sheila, J.; Hayter, P.E.

    1998-01-01

    The photovoltaic (PV) industry is rapidly beginning to recognize the market potential of the buildings sector. New PV-for-buildings products have recently become commercially available, and numerous products that are under development will be introduced within the next 5 years. To ensure that these new products will be adopted and used in common building practices, the PV industry should recognize and address important buildings industry issues. These issues include building codes and standards, after-market servicing, education, and warranties and insurance policies. Photovoltaic systems are also still very expensive. The simplest method for increasing their value for a building is to decrease the building's electrical loads through energy efficiency and conservation. Meeting these goals can only be accomplished through partnerships with the U.S. Department of Energy (DOE), private industry, and public institutions

  20. Enhancing chronic disease management: a review of key issues and strategies.

    Science.gov (United States)

    Willison, Kevin D; Williams, Paul; Andrews, Gavin J

    2007-11-01

    This paper highlights three selected issues and potential strategies towards meeting chronic disease management needs. First, the orientation of the biomedical science model often gives insufficient attention to chronic health care needs. A second issue is that the use of complementary and alternative medicine (CAM) may offer for some an opportunity to enhance their chronic disease management efforts. A third issue is that our understanding of this potential is limited, as many who use CAM do not disclose such use. With reference to proposed solutions/strategies, first, an improved focus to respect patient/client values and goals may encourage people to disclose their use of CAM. Second, a community-based participatory approach shows promise in enhancing communication plus helps integrate CAM within new models of chronic disease management. Lastly, those in public health could help facilitate such an approach plus be a monitor of CAM practices. Overall, this review provides a springboard for further research and practice in CAM and the management of chronic diseases.

  1. Identifying key research objectives to make European forests greener for bats

    Directory of Open Access Journals (Sweden)

    Danilo Russo

    2016-07-01

    Full Text Available Bats are a biodiverse mammal order providing key ecosystem services such as pest suppression, pollination and seed dispersal. Bats are also very sensitive to human actions, and significant declines in many bat populations have been recorded consequently. Many bat species find crucial roosting and foraging opportunities in European forests. Such forests have historically been exploited by humans and are still influenced by harvesting. One of the consequences of this pressure is the loss of key habitat resources, often making forests inhospitable to bats. Despite the legal protection granted to bats across Europe, the impacts of forestry on bats are still often neglected. Because forest exploitation influences forest structure at several spatial scales, economically viable forestry could become more sustainable and even favour bats. We highlight that a positive future for bat conservation that simultaneously benefits forestry is foreseeable, although more applied research is needed to develop sound management. Key future research topics include the detection of factors influencing the carrying capacity of forests, and determining the impacts of forest management and the economic importance of bats in forests. Predictive tools to inform forest managers are much needed, together with greater synergies between forest managers and bat conservationists.

  2. Building capacity in Australian interprofessional health education: perspectives from key health and higher education stakeholders.

    Science.gov (United States)

    Matthews, Lynda R; Pockett, Rosalie B; Nisbet, Gillian; Thistlethwaite, Jill E; Dunston, Roger; Lee, Alison; White, Jill F

    2011-05-01

    A substantial literature engaging with the directions and experiences of stakeholders involved in interprofessional health education exists at the international level, yet almost nothing has been published that documents and analyses the Australian experience. Accordingly, this study aimed to scope the experiences of key stakeholders in health and higher education in relation to the development of interprofessional practice capabilities in health graduates in Australia. Twenty-seven semi-structured interviews and two focus groups of key stakeholders involved in the development and delivery of interprofessional health education in Australian higher education were undertaken. Interview data were coded to identify categories that were organised into key themes, according to principles of thematic analysis. Three themes were identified: the need for common ground between health and higher education, constraints and enablers in current practice, and the need for research to establish an evidence base. Five directions for national development were also identified. The study identified a range of interconnected changes that will be required to successfully mainstream interprofessional education within Australia, in particular, the importance of addressing issues of culture change and the need for a nationally coordinated and research informed approach. These findings reiterate those found in the international literature.

  3. To twist or poke? A method for identifying usability issues with the rotary controller and touch screen for control of in-vehicle information systems.

    Science.gov (United States)

    Harvey, Catherine; Stanton, Neville A; Pickering, Carl A; McDonald, Mike; Zheng, Pengjun

    2011-07-01

    In-vehicle information systems (IVIS) can be controlled by the user via direct or indirect input devices. In order to develop the next generation of usable IVIS, designers need to be able to evaluate and understand the usability issues associated with these two input types. The aim of this study was to investigate the effectiveness of a set of empirical usability evaluation methods for identifying important usability issues and distinguishing between the IVIS input devices. A number of usability issues were identified and their causal factors have been explored. These were related to the input type, the structure of the menu/tasks and hardware issues. In particular, the translation between inputs and on-screen actions and a lack of visual feedback for menu navigation resulted in lower levels of usability for the indirect device. This information will be useful in informing the design of new IVIS, with improved usability. STATEMENT OF RELEVANCE: This paper examines the use of empirical methods for distinguishing between direct and indirect IVIS input devices and identifying usability issues. Results have shown that the characteristics of indirect input devices produce more serious usability issues, compared with direct devices and can have a negative effect on the driver-vehicle interaction.

  4. Several key issues on implementing delay line based TDCs using FPGAs

    International Nuclear Information System (INIS)

    Wu, Jinyuan

    2009-01-01

    Several topics in FPGA delay line based TDCs are discussed in this document. First, FPGA specific issues such as considerations on the delay line choice in different FPGA families, Wave Union Launchers, 'bubble proof' encoding logic, etc. are examined. Next, common problems for both FPGA TDCs and ASIC TDCs such as schemes of coarse time counter implementation, bin-by-bin calibration and noise issues due to single ended signals are discussed. Several resource/power saving design approaches for various processing stages are described in the document.

  5. Key Clinical Features to Identify Girls with "CDKL5" Mutations

    Science.gov (United States)

    Bahi-Buisson, Nadia; Nectoux, Juliette; Rosas-Vargas, Haydee; Milh, Mathieu; Boddaert, Nathalie; Girard, Benoit; Cances, Claude; Ville, Dorothee; Afenjar, Alexandra; Rio, Marlene; Heron, Delphine; Morel, Marie Ange N'Guyen; Arzimanoglou, Alexis; Philippe, Christophe; Jonveaux, Philippe; Chelly, Jamel; Bienvenu, Thierry

    2008-01-01

    Mutations in the human X-linked cyclin-dependent kinase-like 5 ("CDKL5") gene have been shown to cause infantile spasms as well as Rett syndrome (RTT)-like phenotype. To date, less than 25 different mutations have been reported. So far, there are still little data on the key clinical diagnosis criteria and on the natural history of…

  6. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

    Science.gov (United States)

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006-2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones. The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and discover new

  7. Safeguards and security issues at the MRS facility

    International Nuclear Information System (INIS)

    McGuinn, E.; Birch, M.; Jones, J.; Floyd, W.

    1993-01-01

    The U.S. Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) is responsible for disposing of the nation's high level radioactive waste in a way that ensures the protection of the public from any unacceptable radiological risks and the maintenance of the national security. To achieve these objectives, OCRWM plans to institute a Nuclear Regulatory Commission (NRC)-approved security program at its facilities including the Monitored Retrievable Storage (MRS) facility. This program will safeguard nuclear information and provide not only for the physical protection of facilities but also for the nuclear material being handled and stored. Several key regulatory issues were identified during the development of the safeguards and security (S ampersand S) program for the MRS. These issues relate to developing a realistic definition of the security threat at the MRS and establishing a single set of regulatory requirements. Resolution of these issues is important to implement a realistic S ampersand S program who scope is commensurate with the potential risk at the MRS and complies with all appropriate regulatory requirements. OCRWM is working toward a timely resolution of these issues and on the formulation of an S ampersand S program for implementation at the MRS. As an initial step, DOE has proposed an S ampersand S strategy for the MRS based on a set of assumed resolutions to the key regulatory issues. With this approach, the facility designers will be able to evaluate possible S ampersand S concepts for integration into the MRS early in the design process

  8. Nanotechnologies for Climate Friendly Construction – Key Issues and Challenges

    DEFF Research Database (Denmark)

    Andersen, Maj Munch; Geiker, Mette Rica

    2009-01-01

    Expectations as to the climate potentials of nanotechnology are high, none the least related to the construction sector. This paper seeks to highlight key aspects in the early development and application of eco-innovative nanotech solutions in the construction sector, “nanoconstruction”. The paper...

  9. Public perceptions of energy issues in Ontario

    International Nuclear Information System (INIS)

    2004-11-01

    In October 2004, the Environics Research Group conducted a telephone survey of 608 adult Ontarians to collect information on matters regarding energy; consumer confidence and protection; responsibilities of the Ontario Energy Board; and consumer information preferences. This report summarizes the key findings of the survey. According to the survey, the most important electricity and natural gas issue was identified as being price and cost issues, followed by reliability of supply, conservation, keeping utilities publicly owned, finding renewable sources of energy, and over-consumption. The survey revealed that Ontarians show much interest in conserving energy to save money, to protect the environment and ensure future energy supply, but they are generally sceptical that their interests are being protected on electricity and natural gas price issues. At least 9 in 10 Ontarians consider the tasks of the Ontario Energy Board to be important. The majority of Ontarians prefer to receive energy conservation information through the mail and from public regulators over a government department or a company. 10 tabs

  10. Quantum key management

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Richard John; Thrasher, James Thomas; Nordholt, Jane Elizabeth

    2016-11-29

    Innovations for quantum key management harness quantum communications to form a cryptography system within a public key infrastructure framework. In example implementations, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a Merkle signature scheme (using Winternitz one-time digital signatures or other one-time digital signatures, and Merkle hash trees) to constitute a cryptography system. More generally, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a hash-based signature scheme. This provides a secure way to identify, authenticate, verify, and exchange secret cryptographic keys. Features of the quantum key management innovations further include secure enrollment of users with a registration authority, as well as credential checking and revocation with a certificate authority, where the registration authority and/or certificate authority can be part of the same system as a trusted authority for quantum key distribution.

  11. Interpretation of Issues and Voter Decision-Making Strategies: A New Perspective on "Issue-Oriented" Election Coverage.

    Science.gov (United States)

    Domke, David; Shah, Dhavan V.

    1995-01-01

    Finds that voters who ascribed an ethical interpretation to issues were more likely to use a noncompensatory decision-making strategy, which focuses on one or two key issues in the decision-making process, than voters who ascribed a societal interpretation to issues. (SR)

  12. [Key effect genes responding to nerve injury identified by gene ontology and computer pattern recognition].

    Science.gov (United States)

    Pan, Qian; Peng, Jin; Zhou, Xue; Yang, Hao; Zhang, Wei

    2012-07-01

    In order to screen out important genes from large gene data of gene microarray after nerve injury, we combine gene ontology (GO) method and computer pattern recognition technology to find key genes responding to nerve injury, and then verify one of these screened-out genes. Data mining and gene ontology analysis of gene chip data GSE26350 was carried out through MATLAB software. Cd44 was selected from screened-out key gene molecular spectrum by comparing genes' different GO terms and positions on score map of principal component. Function interferences were employed to influence the normal binding of Cd44 and one of its ligands, chondroitin sulfate C (CSC), to observe neurite extension. Gene ontology analysis showed that the first genes on score map (marked by red *) mainly distributed in molecular transducer activity, receptor activity, protein binding et al molecular function GO terms. Cd44 is one of six effector protein genes, and attracted us with its function diversity. After adding different reagents into the medium to interfere the normal binding of CSC and Cd44, varying-degree remissions of CSC's inhibition on neurite extension were observed. CSC can inhibit neurite extension through binding Cd44 on the neuron membrane. This verifies that important genes in given physiological processes can be identified by gene ontology analysis of gene chip data.

  13. MODERNIZING THE PRIVATE LAW. SOME KEY ISSUES IN THE RECENT DRAFT OF THE SPANISH COMMERCIAL CODE

    Directory of Open Access Journals (Sweden)

    Dan VELICU

    2016-05-01

    Full Text Available The last decades were dominated by the idea that an authentic process to modernize the private law means generally the unification of it by renouncing the distinction between civil and commercial law. A few European countries and some American states or provinces followed this path of the unification. However, beyond the will to change and improve the system one may reflect if this kind of modernization is actually really proper. Of course, there are lots of reasons for unification and reasons against it. Is there a possible and real alternative to this wave of unification? The draft of the Spanish commercial code could be a beginning point in order to settle this controversy. For the first time, the lawmakers are trying to replace the actual code with a new modernized one without renouncing the above mentioned distinction. Without claiming that we have entirely analyzed the topic, we propose a brief critical presentation of the major key issue of the draft.

  14. Non-proliferation and safeguards aspects. Key issue paper no. 5

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    This paper examines the current nuclear non-proliferation regime (Section 2) and the issues most likely to arise as the civil nuclear fuel cycle develops over the next 50 years (Section 3). Section 4 deals with fuel cycles and nuclear material inventories. 14 refs.

  15. Breaking chaotic shift key communication via adaptive key identification

    International Nuclear Information System (INIS)

    Ren Haipeng; Han Chongzhao; Liu Ding

    2008-01-01

    This paper proposes an adaptive parameter identification method for breaking chaotic shift key communication from the transmitted signal in public channel. The sensitive dependence property of chaos on parameter mismatch is used for chaos adaptive synchronization and parameter identification. An index function about the synchronization error is defined and conjugate gradient method is used to minimize the index function and to search the transmitter's parameter (key). By using proposed method, secure key is recovered from transmitted signal generated by low dimensional chaos and hyper chaos switching communication. Multi-parameters can also be identified from the transmitted signal with noise

  16. Implications of Key Performance Indicator Issues in Ontario Universities Explored

    Science.gov (United States)

    Chan, Vivian

    2015-01-01

    Since 1998, the Ministry of Training, Colleges and Universities in Ontario, Canada, has required that data on specific key performance indicators (KPIs) be made public by its publicly funded universities. The information is intended to be used by universities to demonstrate their achievements, to improve their programmes and services, and to…

  17. The transportation issue management system: A tool for issue resolution

    International Nuclear Information System (INIS)

    Branch, K.M.; Boryczka, M.K.

    1987-01-01

    During the last decade, issue management programs have been developed and used by a number of large corporations in the United States. These systems have generally been designed to help senior program managers identify issues, develop strategic plans, and resolve issues. These systems involve scanning and abstracting literature to create a database that is then used for 1) issue identification, 2) issue analysis, 3) priority assessment, 4) development of corporate position/strategic options, and 5) action planning and implementation. Most of the existing systems rely on staff to identify trends in the computerized output, analyze the importance of the issue to the company, and assist in developing corporate responses. The Department of Energy has recently developed an issue management system for the Office of Civilian Radioactive Waste Management's (OCRWM) transportation program. This system is designed to help DOE identify institutional issues related to radioactive waste transportation, analyze the issues, and resolve them in a manner that is responsive to interested parties. The system will contain pertinent information from DOE technical reports, other federal documents, correspondence, professional journals, popular literature, newsclips, legislation and testimony. The program is designed around a number of institutional issues including: prenotification, physical protection procedures; highway, rail, and barge routing; inspections and enforcement of shipments; emergency response; liability, cask design and testing; overweight trucks; rail service; modal mix; infrastructure improvements; training standards, and operational procedures

  18. Transboundary Movements of Genetically Modified Organisms and the Cartagena Protocol: Key Issues and Concerns

    Directory of Open Access Journals (Sweden)

    Odile J Lim Tung

    2014-12-01

    Full Text Available Biotechnology or the engineering of the genetic material of species can give way to avenues of possibilities for the benefit of people, fauna and flora but also has the potential of posing untold and undiscovered threats to human beings and other living organisms. One of the first attempts to legislate on international rules on biotechnology can be traced back to article 19 of the Convention on Biological Diversity (CBD in 1992. The CBD is indeed the first international legal instrument apart from the then European Community’s relevant directives to suggest that biotechnology is a matter of concern for the international community while providing a basis upon which more detailed procedures would be elaborated in the field of biosafety. While the CBD includes international rules on access to genetic resources, access to and the transfer of technology, the handling of biotechnology and the distribution of its benefits, it does not include a detailed regulation on genetically modified organisms (GMOs and their possible adverse effects on the environment, human and animal health. It was only with the coming into existence of the Cartagena Protocol on Biosafety (Cartagena Protocol to the CBD in 2000 that the safe transfer, handling and use of living modified organisms (LMOs such as genetically engineered plants, animals, and microbes were at last being catered for, albeit leaving aside the broader categories of GMOs. Due to the need for the negotiators of this protocol to make compromises, there were still key issues on the international biosafety framework pertaining mainly to the scope of the GMOs to be covered by this protocol and by the Advanced Informed Agreement procedure; identification and traceability issues; and liability and redress issues. Nine years after the entry into force of the Cartagena Protocol the transboundary movements of GMOs have clearly increased with new categories of GMOs and genetically modified products to regulate. The

  19. A digest of the Nuclear Safety Division report on the Fukushima Dai-ichi accident seminar (4). Issues identified by the accident

    International Nuclear Information System (INIS)

    Moriyama, Kumiaki; Abe, Kiyoharu

    2013-01-01

    AESJ Nuclear Safety Division published 'Report on the Fukushima Dai-ichi Accident Seminar - what was wrong and what should been down in future-' which would be published as five special articles of the AESJ journal. The Fukushima Dai-ichi accident identified issues of several activities directly related with nuclear safety in the areas of safety design, severe accident management and safety regulations. PRA, operational experiences and safety research could not always contribute safety assurance of nuclear power plant so much. This article (4) summarized technical issues based on related facts of the accident as much as possible and discussed' what was wrong and what should be down in future'. Important issues were identified from defense-in-depth philosophy and lessons learned on safety design were obtained from accident progression analysis. Activities against external events and continuous improvements of safety standards based on latest knowledge were most indispensable. Strong cooperation among experts in different areas was also needed. (T. Tanaka)

  20. METHODOLOGICAL ISSUES OF CLINICAL TRIALS IN THE PEDIATRIC POPULATION

    Directory of Open Access Journals (Sweden)

    S.V. Topolyanskaya

    2010-01-01

    Full Text Available Conducting clinical trials on children population is a challenge both for organizers and pediatricians involved in trials. Difficulties in recruiting patients, a significant heterogenecity of the population, specific side reactions, difficulties in identifying the objective final points warrant the specific nature of designing clinical trials in pediatrics. The article illustrates key issues and methodology aspects: planning, design, control groups, patient recruitment. It stresses the need to carefully consider specific characteristics of a child’s system and multi-disciplinary approach involving a pediatrician at the early stages of planning, preliminary consultations with parent organizations, children and regulators.Key words: clinical trials, methodology, planning, design, patient recruitment, children. (Pediatric Pharmacology. – 2010; 7(5:6-10

  1. Ethical issues in identifying and recruiting participants for familial genetic research.

    Science.gov (United States)

    Beskow, Laura M; Botkin, Jeffrey R; Daly, Mary; Juengst, Eric T; Lehmann, Lisa Soleymani; Merz, Jon F; Pentz, Rebecca; Press, Nancy A; Ross, Lainie Friedman; Sugarman, Jeremy; Susswein, Lisa R; Terry, Sharon F; Austin, Melissa A; Burke, Wylie

    2004-11-01

    Family-based research is essential to understanding the genetic and environmental etiology of human disease. The success of family-based research often depends on investigators' ability to identify, recruit, and achieve a high participation rate among eligible family members. However, recruitment of family members raises ethical concerns due to the tension between protecting participants' privacy and promoting research quality, and guidelines for these activities are not well established. The Cancer Genetics Network Bioethics Committee assembled a multidisciplinary group to explore the scientific and ethical issues that arise in the process of family-based recruitment. The group used a literature review as well as expert opinion to develop recommendations about appropriate approaches to identifying, contacting, and recruiting family members. We conclude that there is no single correct approach, but recommend a balanced approach that takes into account the nature of the particular study as well as its recruitment goals. Recruitment of family members should be viewed as part of the research protocol and should require appropriate informed consent of the already-enrolled participant. Investigators should inform prospective participants why they are being contacted, how information about them was obtained, and what will happen to that information if they decide not to participate. The recruitment process should also be sensitive to the fact that some individuals from families at increased genetic risk will have no prior knowledge of their risk status. These recommendations are put forward to promote further discussion about the advantages and disadvantages of various approaches to family-based recruitment. They suggest a framework for considering alternative recruitment strategies and their implications, as well as highlight areas in need of further empirical research. (c) 2004 Wiley-Liss, Inc.

  2. Two books on dementia care: Risk Assessment and management for living well with dementia, and Key issues in evolving dementia care

    Directory of Open Access Journals (Sweden)

    Gillian Manthorpe

    2013-05-01

    Full Text Available Risk Assessment and Management for Living Well with Dementia. Charlotte L. Clarke, Heather Wilkinson, John Keady and Catherine E. Gibb. Foreword by Murna Downs. Part of the Bradford Dementia Group Good Practice Guides series. London: Jessica Kingsley Publishers, 2011, pp. 128, ISBN: 978-1-84905-005-0Key Issues in Evolving Dementia Care. International Theory-based Policy and Practice. Edited by Anthea Innes, Fiona Kelly and Louise McCabe. Foreword by Professor June Andrews. London: Jessica Kingsley Publishers, 2012, pp. 264, ISBN: 978-1-84905-242-9

  3. Distributed Generation in Power Systems: An Overview and Key Issues

    DEFF Research Database (Denmark)

    Singh, Sri Niwas

    2009-01-01

    quality, etc. However, depending on the system configuration and management, these advantages may not be true. Moreover, due to structural and managerial changes in the electricity supply industry motivated with introduction of completion, the role of small generations distributed in the low...... issues in the DG integration in power systems...

  4. Partitioned key-value store with atomic memory operations

    Energy Technology Data Exchange (ETDEWEB)

    Bent, John M.; Faibish, Sorin; Grider, Gary

    2017-02-07

    A partitioned key-value store is provided that supports atomic memory operations. A server performs a memory operation in a partitioned key-value store by receiving a request from an application for at least one atomic memory operation, the atomic memory operation comprising a memory address identifier; and, in response to the atomic memory operation, performing one or more of (i) reading a client-side memory location identified by the memory address identifier and storing one or more key-value pairs from the client-side memory location in a local key-value store of the server; and (ii) obtaining one or more key-value pairs from the local key-value store of the server and writing the obtained one or more key-value pairs into the client-side memory location identified by the memory address identifier. The server can perform functions obtained from a client-side memory location and return a result to the client using one or more of the atomic memory operations.

  5. Summary report on the FHWA LTBP Workshop to identify bridge substructure performance issues : March 4-6, 2010, in Orlando, FL.

    Science.gov (United States)

    2013-01-01

    The Long-Term Bridge Performance (LTBP) program was created to identify, collect, and analyze researchquality : data on the most critical aspects of bridge performance. To complete a thorough investigation of bridge : performance issues, the Federal ...

  6. High-heat tank safety issue resolution program plan. Revision 2

    International Nuclear Information System (INIS)

    Wang, O.S.

    1994-12-01

    The purpose of this program plan is to provide a guide for selecting corrective actions that will mitigate and/or remediate the high-heat waste tank safety issue for single-shell tank 241-C-106. The heat source of approximately 110,000 Btu/hr is the radioactive decay of the stored waste material (primarily 90 Sr) inadvertently transferred into the tank in the later 1960s. Currently, forced ventilation, with added water to promote thermal conductivity and evaporation cooling, is used for heat removal. The method is very effective and economical. At this time, the only viable solution identified to permanently resolve this safety issue is the removal of heat-generating waste in the tank. This solution is being aggressively pursued as the only remediation method to this safety issue, and tank 241-C-106 has been selected as the first single-shell tank for retrieval. The current cooling method and other alternatives are addressed in this program as means to mitigate this safety issue before retrieval. This program plan has three parts. The first part establishes program objectives and defines safety issue, drivers, and resolution criteria and strategy. The second part evaluates the high-heat safety issue and its mitigation and remediation methods and other alternatives according to resolution logic. The third part identifies major tasks and alternatives for mitigation and resolution of the safety issue. A table of best-estimate schedules for the key tasks is also included in this program plan

  7. Quantum key distribution using three basis states

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 54; Issue 5. Quantum key distribution using three ... This note presents a method of public key distribution using quantum communication of photons that simultaneously provides a high probability that the bits have not been tampered. It is a variant of the quantum ...

  8. Ecotoxicology for risk assessment in arid zones: some key issues.

    Science.gov (United States)

    Everts, J W

    1997-01-01

    In the hot arid zones of the world, ecotoxicological research is in statu nascendi. In these zones, the major sources of contamination by toxicants are: (1) plant protection and vector control in wet zones; (2) large-scale crop protection campaigns in dry and ephemeral wet zones; (3) refuse and obsolete pesticides in dry zones; and (4) mining. Economic development in many of these zones requires an adequate knowledge of certain basic principles, i.e., where extrapolating existing knowledge does not apply. The vulnerability of ecosystems to contaminants is closely related to water flow. In dry areas, species are susceptible to factors that interfere with the ecophysiological properties regulating water loss. Most hot arid areas are found at low latitudes where temperatures show striking extremes both in time and space. Living organisms are physiologically resistant and/or show adaptive behavior to these temperature extremes. Very little is known about the effects of toxicants on these key resistant and adaptive functions, although by extrapolation a few assumptions can be made. The effects of hyperthermia, for instance, can be aggravated by GSH depleting substances, and the temporary disabling effects characteristic of many pesticides may prove fatal under these circumstances. Most wet areas show a spatial concentration of both human activity and wildlife. In mesic zones, the contamination of water represents a health risk to both humans and other living organisms. The vast majority of aquatic communities are those inhabiting temporary pools and streams. Their populations are characterized by short reproductive cycles and/or long dormant stages. Toxicants affecting growth in these areas have been shown to have a deleterious effect. In a synthesis of existing knowledge the most prominent gaps are identified and priorities for further research are made.

  9. Examining the Role of Mental Health and Clinical Issues within Talent Development

    Directory of Open Access Journals (Sweden)

    Andy eHill

    2016-01-01

    Full Text Available Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8 experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with

  10. Examining the Role of Mental Health and Clinical Issues within Talent Development.

    Science.gov (United States)

    Hill, Andy; MacNamara, Áine; Collins, Dave; Rodgers, Sheelagh

    2015-01-01

    Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development (TID) become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8) experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with coaches

  11. Examining the Role of Mental Health and Clinical Issues within Talent Development

    Science.gov (United States)

    Hill, Andy; MacNamara, Áine; Collins, Dave; Rodgers, Sheelagh

    2016-01-01

    Although significant research supports the association between physical activity and mental wellbeing, current literature acknowledges that athletes are no less susceptible to mental illness than the general population. Despite welcomed initiatives aimed at improving mental health within elite sport, these programs often fail to target young athletes; an important concern given that the genesis of many mental illnesses are recognized to occur during this critical period. Given the importance of early intervention and effective treatment, and the potentially devastating consequences of clinical issues going undiagnosed, the implications for talent identification and development (TID) become obvious. With this in mind, this study sought to examine the range of mental health issues that may impact upon developing athletes and potential consequences for the development process, specific risk and protective factors associated with talent development, along with an examination of current practices concerning the identification of mental health issues in such environments. Qualitative interviews were conducted with purposively sampled clinicians (n = 8) experienced in working with adolescents and/or young athletes. Inductive content analysis was undertaken, identifying four main themes: key behavioral indicators; associated risk factors; associated protective factors; and issues around identification and diagnosis. Key behavioral indicators included behavioral change, along with behaviors associated with eating disorders, anxiety and depression. Risk factors centered on family background, the performance environment, and issues surrounding adolescence. Protective factors were primarily social in nature. Finally, a lack of awareness and understanding of clinical issues, multiple causes of symptoms, non-disclosure and the need for triangulation of assessment were identified. The need for improved identification and intervention strategies was apparent, with coaches

  12. Adapting oecd aquatic toxicity tests for use with manufactured nanomaterials: key issues and consensus recommendations

    DEFF Research Database (Denmark)

    Petersen, Elijah J.; Diamond, Stephen A.; Kennedy, Alan J.

    2015-01-01

    . Scientifically based risk assessment for MNs necessitates development of reproducible, standardized hazard testing methods such as those provided by the Organization of Economic Cooperation and Development (OECD). Currently, there is no comprehensive guidance on how to best address testing issues specific to MN...... particulate, fibrous, or colloidal properties. This paper summarizes the findings from an expert workshop convened to develop a guidance document that addresses the difficulties encountered when testing MNs using aquatic and sediment OECD test guidelines. Critical components were identified by workshop...... participants that require specific guidance for MN testing: preparation of dispersions, dose metrics, the importance and challenges associated with maintaining and monitoring exposure levels, and the need for reliable methods to quantify MNs in complex media. To facilitate a scientific advance...

  13. Public engagement with CCS: barriers, key issues and ways forward

    Science.gov (United States)

    Xenias, Dimitrios

    2017-04-01

    Although Carbon Capture and Storage (CCS) is recognised as a crucial transition technology to a low-carbon world, it has not been popular with the public or some governments (e.g. the UK). Also, despite its use in industrial processes for decades, CCS remains and unfamiliar technology for most publics. It is therefore important to foster top-down and bottom-up acceptance of large scale CCS. In an exploratory round of interviews we canvassed the views of British, Dutch, German and Norwegian experts (N=13) with previous experience in public engagement with CCS. They identified barriers and drivers for CCS deployment and public engagement with CCS. Thematic analysis revealed a small number of recurrent issues, including: (a) lack of political leadership on CCS; (b) lack of public knowledge on relevant technologies and (c) difficulty communicating why CCS is necessary. Emphasis on these barriers varied with the level of experts' engagement with the public. More interestingly, although most experts agreed on the importance of public engagement, their views divided between 'why' engage and 'how' best to do this. In a subsequent expert survey (N=99) interview findings were reinforced: public support was seen as important for CCS roll-out (72%), though lower than political support and funding. The survey also showed that local public was expected to experience most risks, while global public will experience most benefits; whereas local business is seen to benefit more than global. Experts were overwhelmingly positive about CCS - risks outweigh benefits, and are confident that CCS will play a major role in climate change mitigation (along with reduced energy demand and renewables). These findings will be expanded on and triangulated in a follow-up public survey which will benefit those involved with public engagement with CCS.

  14. Evaluation of Adult Literacy Education in the United States: A Review of Methodological Issues

    Science.gov (United States)

    Shi, Yan; Tsang, Mun C.

    2008-01-01

    This is a critical review of methodological issues in the evaluation of adult literacy education programs in the United States. It addresses the key research questions: What are the appropriate methods for evaluating these programs under given circumstances. It identifies 15 evaluation studies that are representative of a range of adult literacy…

  15. Key identifiers and spelling conventions in MXit-lingo as found in conversations with Dr Math

    Directory of Open Access Journals (Sweden)

    Laurie Butgereit

    2012-07-01

    Full Text Available Different human languages look different from other human languages. To use a term from the computer industry, each human language has its own “look and feel”. European English speakers can easily recognise a phrase such as “Comment allez-vous?” as being written in French while the phrase “¿Habla usted español?” is written in Spanish. Each language has its own letter frequencies, word frequencies and other identifiers. This paper describes key identifiers in MXit lingo as found in Dr Math conversations. MXit is a mobile instant messaging system which originated in South Africa and is expanding to other countries. Dr Math is a mobile tutoring system which uses MXit as a communication protocol. Primary and secondary school pupils can receive help with the mathematics homework using the Dr Math tutoring system. The pupils use MXit on their cell phones and the tutors use traditional Internet workstations. After exploring how MXit lingo is written, this paper will briefly explore why MXit lingo is written the way it is. By identifying and describing the orthographic conventions visible in the spelling of MXit lingo, although with some theoretical support, insight into the purposeful and functional nature of written, mobile communication will be revealed. In highlighting spelling that is influenced by Black South African English, an attempt will be made to contribute to the empirical development of a field of study that explores the construction of words used in South African mobile communication. Keywords: MXit, Math, letters, writing, orthography Disciplines: Linguistics, mathematics, information technology

  16. Conference communication. Managing change in tourism destinations: Key issues and current trends.

    OpenAIRE

    Mariani, M.M.; Buhalis, Dimitrios; Longhi, C.; Vitouladiti, O.

    2013-01-01

    This conference communication illustrates the major outcomes emerging from the EIASM Conference on Tourism Management and Tourism Related Issues held in Nice (France), September 20-21, 2012. While a number of managerial issues pertaining to the tourism field were dealt with, this communication covers three specific areas of interest for destination management and marketing: (1) the increasing competition among tourism destinations and the rise and consolidation of BRIC countries as outbound t...

  17. OCWM Transportation Institutional Program Update on Collaborative Efforts with Key Stakeholders

    International Nuclear Information System (INIS)

    Saris, E.; Austin, P.; Offner, J.J.

    2004-01-01

    The Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) created the Office of National Transportation in 2003 recognizing the need to revitalize and accelerate development of the transportation system. The Department has made a commitment to work through a collaborative planning process before developing specific policies and procedures and making transportation decisions. OCRWM has begun to build the institutional framework to support development of this transportation system. Interactions with stakeholders have been initiated. The authors describe the key stakeholders, identified issues, regional and national planning activities, and mechanisms for interaction

  18. Body Dysmorphic Disorder: Some Key Issues for DSM-V

    Science.gov (United States)

    Phillips, Katharine A.; Wilhelm, Sabine; Koran, Lorrin M.; Didie, Elizabeth R.; Fallon, Brian A.; Feusner, Jamie; Stein, Dan J.

    2014-01-01

    Body dysmorphic disorder (BDD), a distressing or impairing preoccupation with an imagined or slight defect in appearance, has been described for more than a century and increasingly studied over the past several decades. This paper provides a focused review of issues pertaining to BDD that are relevant to DSM-V. The review presents a number of options and preliminary recommendations to be considered for DSM-V: 1) Criterion A may benefit from some rewording, without changing its focus or meaning; 2) Potential disadvantages of adding a new criterion to reflect BDD compulsive behaviors seem to outweigh potential advantages, but adding such a criterion remains an option that can be considered; 3) A clinical significance criterion seems necessary for BDD to differentiate it from normal appearance concerns; 4) BDD and eating disorders have some overlapping features and need to be differentiated; some minor changes to DSM-IV’s criterion C are suggested; 5) BDD should not be broadened to include body integrity identity disorder (apotemnophilia) or olfactory reference syndrome; 6) There is no compelling evidence for including diagnostic features or subtypes that are specific to gender-related, age-related, or cultural manifestations of BDD; 7) Adding muscle dysmorphia as a specifier may have clinical utility; and 8) The ICD-10 criteria for hypochondriacal disorder are not suitable for BDD, and there is no empirical evidence that BDD and hypochondriasis are the same disorder. The issue of how BDD’s delusional variant should be classified in DSM-V is briefly discussed and will be addressed more extensively in a separate paper. PMID:20533368

  19. Body dysmorphic disorder: some key issues for DSM-V.

    Science.gov (United States)

    Phillips, Katharine A; Wilhelm, Sabine; Koran, Lorrin M; Didie, Elizabeth R; Fallon, Brian A; Feusner, Jamie; Stein, Dan J

    2010-06-01

    Body dysmorphic disorder (BDD), a distressing or impairing preoccupation with an imagined or slight defect in appearance, has been described for more than a century and increasingly studied over the past several decades. This article provides a focused review of issues pertaining to BDD that are relevant to DSM-V. The review presents a number of options and preliminary recommendations to be considered for DSM-V: (1) Criterion A may benefit from some rewording, without changing its focus or meaning; (2) There are both advantages and disadvantages to adding a new criterion to reflect compulsive BDD behaviors; this possible addition requires further consideration; (3) A clinical significance criterion seems necessary for BDD to differentiate it from normal appearance concerns; (4) BDD and eating disorders have some overlapping features and need to be differentiated; some minor changes to DSM-IV's criterion C are suggested; (5) BDD should not be broadened to include body integrity identity disorder (apotemnophilia) or olfactory reference syndrome; (6) There is no compelling evidence for including diagnostic features or subtypes that are specific to gender-related, age-related, or cultural manifestations of BDD; (7) Adding muscle dysmorphia as a specifier may have clinical utility; and (8) The ICD-10 criteria for hypochondriacal disorder are not suitable for BDD, and there is no empirical evidence that BDD and hypochondriasis are the same disorder. The issue of how BDD's delusional variant should be classified in DSM-V is briefly discussed and will be addressed more extensively in a separate article. (c) 2010 Wiley-Liss, Inc.

  20. Gender equality and sustainable human development are key issues.

    Science.gov (United States)

    Ando, H

    1995-01-01

    In a message to the Indochina Women's Parliamentarians Meeting, Hirofumi Ando, Deputy Executive Director of the United Nations Family Planning Association (UNFPA), encouraged participants to link gender equality and development issues. Ando noted that many of the goals of the 1994 International Conference on Population and Development imply recognition of the need to redress gender inequalities and empower women. The Program of Action adopted in Cairo requires countries to achieve universal access to primary education and reproductive health care services. Parliamentarians in attendance were urged to mobilize the financial resources and political will necessary to implement programs in these areas.

  1. NAGRADATA. Code key. Geology

    International Nuclear Information System (INIS)

    Mueller, W.H.; Schneider, B.; Staeuble, J.

    1984-01-01

    This reference manual provides users of the NAGRADATA system with comprehensive keys to the coding/decoding of geological and technical information to be stored in or retreaved from the databank. Emphasis has been placed on input data coding. When data is retreaved the translation into plain language of stored coded information is done automatically by computer. Three keys each, list the complete set of currently defined codes for the NAGRADATA system, namely codes with appropriate definitions, arranged: 1. according to subject matter (thematically) 2. the codes listed alphabetically and 3. the definitions listed alphabetically. Additional explanation is provided for the proper application of the codes and the logic behind the creation of new codes to be used within the NAGRADATA system. NAGRADATA makes use of codes instead of plain language for data storage; this offers the following advantages: speed of data processing, mainly data retrieval, economies of storage memory requirements, the standardisation of terminology. The nature of this thesaurian type 'key to codes' makes it impossible to either establish a final form or to cover the entire spectrum of requirements. Therefore, this first issue of codes to NAGRADATA must be considered to represent the current state of progress of a living system and future editions will be issued in a loose leave ringbook system which can be updated by an organised (updating) service. (author)

  2. Nuclear fuel assurance: origins, trends, and policy issues

    International Nuclear Information System (INIS)

    Neff, T.L.; Jacoby, H.D.

    1979-02-01

    The economic, technical and political issues which bear on the security of nuclear fuel supply internationally are addressed. The structure of international markets for nuclear fuel is delineated; this includes an analysis of the political constraints on fuel availability, especially the connection to supplier nonproliferation policies. The historical development of nuclear fuel assurance problems is explored and an assessment is made of future trends in supply and demand and in the political context in which fuel trade will take place in the future. Finally, key events and policies which will affect future assurance are identified

  3. Tic disorders: some key issues for DSM-V.

    Science.gov (United States)

    Walkup, John T; Ferrão, Ygor; Leckman, James F; Stein, Dan J; Singer, Harvey

    2010-06-01

    This study provides a focused review of issues that are relevant to the nosology of the tic disorders and presents preliminary recommendations to be considered for DSM-V. The recommended changes are designed to clarify and simplify the diagnostic criteria, reduce the use of the residual category, tic disorder not otherwise specified, and are not intended to alter substantially clinical practice or the continuity of past and future research. Specific recommendations include: (1) a more precise definition of motor and vocal tics; (2) simplification of the duration criterion for the tic disorders; (3) revising the term "transient tic disorder" for those with tic symptoms of less than 12-month duration; (4) establishing new tic disorder categories for those with substance induced tic disorder and tic disorder due to a general medical condition; and (5) including a motor tic only and vocal tic only specifier for the chronic motor or vocal tic disorder category. (c) 2010 Wiley-Liss, Inc.

  4. Analysis of Key Factors Driving Japan’s Military Normalization

    Science.gov (United States)

    2017-09-01

    no change to our policy of not giving in to terrorism.”40 Though the prime minister was democratically supported, Koizumi’s leadership style took...of the key driving factors of Japan’s normalization. The areas of prime ministerial leadership , regional security threats, alliance issues, and...analysis of the key driving factors of Japan’s normalization. The areas of prime ministerial leadership , regional security threats, alliance issues, and

  5. An Improved Methodology to Overcome Key Issues in Human Fecal Metagenomic DNA Extraction

    Directory of Open Access Journals (Sweden)

    Jitendra Kumar

    2016-12-01

    Full Text Available Microbes are ubiquitously distributed in nature, and recent culture-independent studies have highlighted the significance of gut microbiota in human health and disease. Fecal DNA is the primary source for the majority of human gut microbiome studies. However, further improvement is needed to obtain fecal metagenomic DNA with sufficient amount and good quality but low host genomic DNA contamination. In the current study, we demonstrate a quick, robust, unbiased, and cost-effective method for the isolation of high molecular weight (>23 kb metagenomic DNA (260/280 ratio >1.8 with a good yield (55.8 ± 3.8 ng/mg of feces. We also confirm that there is very low human genomic DNA contamination (eubacterial: human genomic DNA marker genes = 227.9:1 in the human feces. The newly-developed method robustly performs for fresh as well as stored fecal samples as demonstrated by 16S rRNA gene sequencing using 454 FLX+. Moreover, 16S rRNA gene analysis indicated that compared to other DNA extraction methods tested, the fecal metagenomic DNA isolated with current methodology retains species richness and does not show microbial diversity biases, which is further confirmed by qPCR with a known quantity of spike-in genomes. Overall, our data highlight a protocol with a balance between quality, amount, user-friendliness, and cost effectiveness for its suitability toward usage for culture-independent analysis of the human gut microbiome, which provides a robust solution to overcome key issues associated with fecal metagenomic DNA isolation in human gut microbiome studies.

  6. The Key to School Security.

    Science.gov (United States)

    Hotle, Dan

    1993-01-01

    In addition to legislative accessibility requirements, other security issues facing school administrators who select a security system include the following: access control; user friendliness; durability or serviceability; life safety precautions; possibility of vandalism, theft, and tampering; and key control. Offers steps to take in considering…

  7. The study of key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring

    Science.gov (United States)

    Tu, Rui; Zhang, Pengfei; Zhang, Rui; Liu, Jinhai

    2016-08-01

    This paper has studied the key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring. The validations show that the consistence of the coordinate system must be considered firstly to exclude the system bias between GNSS and strong-motion. The GNSS sampling rate is suggested about 1-5 Hz, and we should give the strong-motion's baseline shift with a larger dynamic noise as its variation is very swift. The initialization time of solving the baseline shift is less than one minute, and ambiguity resolution strategy is not greatly improved the solution. The data quality is very important for the solution, we advised to use multi-frequency and multi-system observations. These ideas give an important guide for real-time earthquake monitoring and early warning by the tight integration of GNSS and strong-motion records.

  8. A strategy study on the technology development for key nuclear structural materials

    International Nuclear Information System (INIS)

    Hong, Jun Hwa; Jeong, Youg Hwan; Kim, Tae Kyu

    2012-01-01

    In order to realize the advanced long-life PWRs and new Generation-IV nuclear systems, it is pre-requisite to establish or ensure the several key materials technology. In this study, we proposed the several key needs and directions for the key materials issues. Each issue is envisioned and described below. 1) Development of innovative nuclear structural materials with extreme environment-resistance for advanced G-IV systems 2) Improvement/development of key reactor materials for advanced and long -life PWRs. 3) Development of technologies against nuclear materials aging degradation

  9. Clinical Trials: A Crucial Key to Human Health Research

    Science.gov (United States)

    ... Past Issues Clinical Trials: A Crucial Key to Human Health Research Past Issues / Summer 2006 Table of Contents ... Javascript on. Photo: PhotoDisc At the forefront of human health research today are clinical trials—studies that use ...

  10. Design-based research – issues in connecting theory, research and practice

    DEFF Research Database (Denmark)

    Kolmos, Anette

    2015-01-01

    the gap. But is this as easy as it sounds? The purpose of the article is to identify and discuss issues involved in applying DBR. The article is based on methodology chapters and essays from three PhD studies applying the DBR framework to implement problem and project based learning (PBL). The findings......During the last 20 years, design-based research (DBR) has become a popular methodology for connecting educational theory, research and practice. The missing link between educational theory, research and educational practice is an ongoing issue and DBR is seen as an integrated methodology to bridge...... indicate several key issues at both the scientific and personal level. Scientifically, the main issues are contribution to theory and the role of the researcher. At the personal level, it is an investment beyond normal research procedures to involve yourself as a researcher in curriculum change....

  11. Il governo della performance dei processi di business : dai Key Performance Indicators ai Key Risk Indicators

    OpenAIRE

    Sergio Beretta; Saverio Bozzolan

    2013-01-01

    The recent paper issued by COSO ["Developing Key Risk Indicators to Strengthen Enterprise Risk Management" (Coso, 2010)] is the starting point of this article whose aim is to discuss the relevance of the business process dimension in the design and implementation of Key Risk Indicators. The Authors analyze the reasons of the systematic underestimation of the business process dimension in the COSO papers and debate the implications that the explicit consideration of the business process dimens...

  12. A Recommended Set of Key Arctic Indicators

    Science.gov (United States)

    Stanitski, D.; Druckenmiller, M.; Fetterer, F. M.; Gerst, M.; Intrieri, J. M.; Kenney, M. A.; Meier, W.; Overland, J. E.; Stroeve, J.; Trainor, S.

    2017-12-01

    The Arctic is an interconnected and environmentally sensitive system of ice, ocean, land, atmosphere, ecosystems, and people. From local to pan-Arctic scales, the area has already undergone major changes in physical and societal systems and will continue at a pace that is greater than twice the global average. Key Arctic indicators can quantify these changes. Indicators serve as the bridge between complex information and policy makers, stakeholders, and the general public, revealing trends and information people need to make important socioeconomic decisions. This presentation evaluates and compiles more than 70 physical, biological, societal and economic indicators into an approachable summary that defines the changing Arctic. We divided indicators into "existing," "in development," "possible," and "aspirational". In preparing a paper on Arctic Indicators for a special issue of the journal Climatic Change, our group established a set of selection criteria to identify indicators to specifically guide decision-makers in their responses to climate change. A goal of the analysis is to select a manageable composite list of recommended indicators based on sustained, reliable data sources with known user communities. The selected list is also based on the development of a conceptual model that identifies components and processes critical to our understanding of the Arctic region. This list of key indicators is designed to inform the plans and priorities of multiple groups such as the U.S. Global Change Research Program (USGCRP), Interagency Arctic Research Policy Committee (IARPC), and the Arctic Council.

  13. Summary of SMIRT20 Preconference Topical Workshop - Identifying Structural Issues in Advanced Reactors

    International Nuclear Information System (INIS)

    Richins, William; Novascone, Stephen; O'Brien, Cheryl

    2009-01-01

    The Idaho National Laboratory (INL, USA) and IASMiRT sponsored an international forum Nov 5-6, 2008 in Porvoo, Finland for nuclear industry, academic, and regulatory representatives to identify structural issues in current and future advanced reactor design, especially for extreme conditions and external threats. The purpose of this Topical Workshop was to articulate research, engineering, and regulatory Code development needs. The topics addressed by the Workshop were selected to address critical industry needs specific to advanced reactor structures that have long lead times and can be the subject of future SMiRT technical sessions. The topics were; (1) structural/materials needs for extreme conditions and external threats in contemporary (Gen. III) and future (Gen. IV and NGNP) advanced reactors and (2) calibrating simulation software and methods that address topic 1. The workshop discussions and research needs identified are presented. The Workshop successfully produced interactive discussion on the two topics resulting in a list of research and technology needs. It is recommended that IASMiRT communicate the results of the discussion to industry and researchers to encourage new ideas and projects. In addition, opportunities exist to retrieve research reports and information that currently exists, and encourage more international cooperation and collaboration. It is recommended that IASMiRT continue with an off-year workshop series on select topics.

  14. Projecting biodiversity and wood production in future forest landscapes: 15 key modeling considerations.

    Science.gov (United States)

    Felton, Adam; Ranius, Thomas; Roberge, Jean-Michel; Öhman, Karin; Lämås, Tomas; Hynynen, Jari; Juutinen, Artti; Mönkkönen, Mikko; Nilsson, Urban; Lundmark, Tomas; Nordin, Annika

    2017-07-15

    A variety of modeling approaches can be used to project the future development of forest systems, and help to assess the implications of different management alternatives for biodiversity and ecosystem services. This diversity of approaches does however present both an opportunity and an obstacle for those trying to decide which modeling technique to apply, and interpreting the management implications of model output. Furthermore, the breadth of issues relevant to addressing key questions related to forest ecology, conservation biology, silviculture, economics, requires insights stemming from a number of distinct scientific disciplines. As forest planners, conservation ecologists, ecological economists and silviculturalists, experienced with modeling trade-offs and synergies between biodiversity and wood biomass production, we identified fifteen key considerations relevant to assessing the pros and cons of alternative modeling approaches. Specifically we identified key considerations linked to study question formulation, modeling forest dynamics, forest processes, study landscapes, spatial and temporal aspects, and the key response metrics - biodiversity and wood biomass production, as well as dealing with trade-offs and uncertainties. We also provide illustrative examples from the modeling literature stemming from the key considerations assessed. We use our findings to reiterate the need for explicitly addressing and conveying the limitations and uncertainties of any modeling approach taken, and the need for interdisciplinary research efforts when addressing the conservation of biodiversity and sustainable use of environmental resources. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Ethical issues in the export, storage and reuse of human biological samples in biomedical research: perspectives of key stakeholders in Ghana and Kenya.

    Science.gov (United States)

    Tindana, Paulina; Molyneux, Catherine S; Bull, Susan; Parker, Michael

    2014-10-18

    For many decades, access to human biological samples, such as cells, tissues, organs, blood, and sub-cellular materials such as DNA, for use in biomedical research, has been central in understanding the nature and transmission of diseases across the globe. However, the limitations of current ethical and regulatory frameworks in sub-Saharan Africa to govern the collection, export, storage and reuse of these samples have resulted in inconsistencies in practice and a number of ethical concerns for sample donors, researchers and research ethics committees. This paper examines stakeholders' perspectives of and responses to the ethical issues arising from these research practices. We employed a qualitative strategy of inquiry for this research including in-depth interviews and focus group discussions with key research stakeholders in Kenya (Nairobi and Kilifi), and Ghana (Accra and Navrongo). The stakeholders interviewed emphasised the compelling scientific importance of sample export, storage and reuse, and acknowledged the existence of some structures governing these research practices, but they also highlighted the pressing need for a number of practical ethical concerns to be addressed in order to ensure high standards of practice and to maintain public confidence in international research collaborations. These concerns relate to obtaining culturally appropriate consent for sample export and reuse, understanding cultural sensitivities around the use of blood samples, facilitating a degree of local control of samples and sustainable scientific capacity building. Drawing on these findings and existing literature, we argue that the ethical issues arising in practice need to be understood in the context of the interactions between host research institutions and local communities and between collaborating institutions. We propose a set of 'key points-to-consider' for research institutions, ethics committees and funding agencies to address these issues.

  16. Lay and professional stakeholder involvement in scoping palliative care issues: Methods used in seven European countries.

    Science.gov (United States)

    Brereton, Louise; Ingleton, Christine; Gardiner, Clare; Goyder, Elizabeth; Mozygemba, Kati; Lysdahl, Kristin Bakke; Tummers, Marcia; Sacchini, Dario; Leppert, Wojciech; Blaževičienė, Aurelija; van der Wilt, Gert Jan; Refolo, Pietro; De Nicola, Martina; Chilcott, James; Oortwijn, Wija

    2017-02-01

    Stakeholders are people with an interest in a topic. Internationally, stakeholder involvement in palliative care research and health technology assessment requires development. Stakeholder involvement adds value throughout research (from prioritising topics to disseminating findings). Philosophies and understandings about the best ways to involve stakeholders in research differ internationally. Stakeholder involvement took place in seven countries (England, Germany, Italy, Lithuania, the Netherlands, Norway and Poland). Findings informed a project that developed concepts and methods for health technology assessment and applied these to evaluate models of palliative care service delivery. To report on stakeholder involvement in the INTEGRATE-HTA project and how issues identified informed project development. Using stakeholder consultation or a qualitative research design, as appropriate locally, stakeholders in seven countries acted as 'advisors' to aid researchers' decision making. Thematic analysis was used to identify key issues across countries. A total of 132 stakeholders (82 professionals and 50 'lay' people) aged ⩾18 participated in individual face-to-face or telephone interviews, consultation meetings or focus groups. Different stakeholder involvement methods were used successfully to identify key issues in palliative care. A total of 23 issues common to three or more countries informed decisions about the intervention and comparator of interest, sub questions and specific assessments within the health technology assessment. Stakeholders, including patients and families undergoing palliative care, can inform project decision making using various involvement methods according to the local context. Researchers should consider local understandings about stakeholder involvement as views of appropriate and feasible methods vary. Methods for stakeholder involvement, especially consultation, need further development.

  17. Resilience Analysis of Key Update Strategies for Resource-Constrained Networks

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    2011-01-01

    Severe resource limitations in certain types of networks lead to various open issues in security. Since such networks usually operate in unattended or hostile environments, revoking the cryptographic keys and establishing (also distributing) new keys – which we refer to as key update – is a criti...

  18. Ergonomics issues in national identity card for homeland security.

    Science.gov (United States)

    Yeow, Paul H P; Yuen, Y Y; Loo, W H

    2013-09-01

    Ever since the 9/11 terrorist attack, many countries are considering the use of smart national identity card (SNIC) which has the ability to identify terrorists due to its biometric verification function. However, there are many ergonomics issues in the use of SNIC, e.g. card credibility. This research presents a case study survey of Malaysian users. Although most citizens (>96%) own MyKad (Malaysia SNIC), many do not carry it around and use its applications. This defeats one of its main purposes, i.e. combating terrorism. Thus, the research investigates ergonomics issues affecting the citizens' Intention to Use (ITU) MyKad for homeland security by using an extended technology acceptance model. Five hundred questionnaires were collected and analysed using structural equation modelling. Results show that perceived credibility and performance expectancy are the key issues. The findings provide many countries with insights into methods of addressing ergonomics issues and increasing adoption of SNIC for homeland security. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  19. Ethical issues associated with medical tourism in Africa

    Science.gov (United States)

    Mogaka, John J. O.; Mupara, Lucia; Tsoka-Gwegweni, Joyce M

    2017-01-01

    ABSTRACT Global disparities in medical technologies, laws, economic inequities, and social–cultural differences drive medical tourism (MT), the practice of travelling to consume healthcare that is either too delayed, unavailable, unaffordable or legally proscribed at home. Africa is simultaneously a source and destination for MT. MT however, presents a new and challenging health ethics frontier, being largely unregulated and characterized by policy contradictions, minority discrimination and conflict of interest among role-players. This article assesses the level of knowledge of MT and its associated ethical issues in Africa; it also identifies critical research gaps on the subject in the region. Exploratory design guided by Arksey and O’Malley’s (2005) framework was used. Key search terms and prior determined exclusion/inclusion criteria were used to identify relevant literature sources. Fifty-seven articles met the inclusion criteria. Distributive justice, healthcare resource allocation, experimental treatments and organ transplant were the most common ethical issues of medical tourism in Africa. The dearth of robust engagement of MT and healthcare ethics, as identified through this review, calls for more rigorous research on this subject. Although the bulk of the medical tourism industry is driven by global legal disparities based on ethical considerations, little attention has been given to this subject. PMID:28740618

  20. Ethical issues associated with medical tourism in Africa.

    Science.gov (United States)

    Mogaka, John J O; Mupara, Lucia; Tsoka-Gwegweni, Joyce M

    2017-01-01

    Global disparities in medical technologies, laws, economic inequities, and social-cultural differences drive medical tourism (MT), the practice of travelling to consume healthcare that is either too delayed, unavailable, unaffordable or legally proscribed at home. Africa is simultaneously a source and destination for MT. MT however, presents a new and challenging health ethics frontier, being largely unregulated and characterized by policy contradictions, minority discrimination and conflict of interest among role-players. This article assesses the level of knowledge of MT and its associated ethical issues in Africa; it also identifies critical research gaps on the subject in the region. Exploratory design guided by Arksey and O'Malley's (2005) framework was used. Key search terms and prior determined exclusion/inclusion criteria were used to identify relevant literature sources. Fifty-seven articles met the inclusion criteria. Distributive justice, healthcare resource allocation, experimental treatments and organ transplant were the most common ethical issues of medical tourism in Africa. The dearth of robust engagement of MT and healthcare ethics, as identified through this review, calls for more rigorous research on this subject. Although the bulk of the medical tourism industry is driven by global legal disparities based on ethical considerations, little attention has been given to this subject.

  1. Virtual Reality and Its Potential Use in Special Education. Identifying Emerging Issues and Trends in Technology for Special Education.

    Science.gov (United States)

    Woodward, John

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the possible contributions of virtual reality technology to educational services for students with disabilities. An example of the use of virtual reality in medical imaging introduces the paper and leads to a brief review of…

  2. A Polynomial Subset-Based Efficient Multi-Party Key Management System for Lightweight Device Networks.

    Science.gov (United States)

    Mahmood, Zahid; Ning, Huansheng; Ghafoor, AtaUllah

    2017-03-24

    Wireless Sensor Networks (WSNs) consist of lightweight devices to measure sensitive data that are highly vulnerable to security attacks due to their constrained resources. In a similar manner, the internet-based lightweight devices used in the Internet of Things (IoT) are facing severe security and privacy issues because of the direct accessibility of devices due to their connection to the internet. Complex and resource-intensive security schemes are infeasible and reduce the network lifetime. In this regard, we have explored the polynomial distribution-based key establishment schemes and identified an issue that the resultant polynomial value is either storage intensive or infeasible when large values are multiplied. It becomes more costly when these polynomials are regenerated dynamically after each node join or leave operation and whenever key is refreshed. To reduce the computation, we have proposed an Efficient Key Management (EKM) scheme for multiparty communication-based scenarios. The proposed session key management protocol is established by applying a symmetric polynomial for group members, and the group head acts as a responsible node. The polynomial generation method uses security credentials and secure hash function. Symmetric cryptographic parameters are efficient in computation, communication, and the storage required. The security justification of the proposed scheme has been completed by using Rubin logic, which guarantees that the protocol attains mutual validation and session key agreement property strongly among the participating entities. Simulation scenarios are performed using NS 2.35 to validate the results for storage, communication, latency, energy, and polynomial calculation costs during authentication, session key generation, node migration, secure joining, and leaving phases. EKM is efficient regarding storage, computation, and communication overhead and can protect WSN-based IoT infrastructure.

  3. Mapping the inbound logistics of the refineries & terminals (plants) onshore at StatoilHydro, identify main problems and issues and suggest quick wins and possible solutions

    OpenAIRE

    Julien, Ane Sofie

    2011-01-01

    Master's thesis in Firm management The aim of this paper is to identify main problems and issues in the supply chain of the inbound logistics at StatoilHydro’s onshore plants. The identification will be based on a mapping of the chain, where value added activity is in focus. The problems and issues will be evaluated and prioritized according to suggested quick wins and possible solutions will be identified. The recommended solution will be based on the elaborated theory of muda...

  4. Experimental infections with Mycoplasma agalactiae identify key factors involved in host-colonization.

    Directory of Open Access Journals (Sweden)

    Eric Baranowski

    Full Text Available Mechanisms underlying pathogenic processes in mycoplasma infections are poorly understood, mainly because of limited sequence similarities with classical, bacterial virulence factors. Recently, large-scale transposon mutagenesis in the ruminant pathogen Mycoplasma agalactiae identified the NIF locus, including nifS and nifU, as essential for mycoplasma growth in cell culture, while dispensable in axenic media. To evaluate the importance of this locus in vivo, the infectivity of two knock-out mutants was tested upon experimental infection in the natural host. In this model, the parental PG2 strain was able to establish a systemic infection in lactating ewes, colonizing various body sites such as lymph nodes and the mammary gland, even when inoculated at low doses. In these PG2-infected ewes, we observed over the course of infection (i the development of a specific antibody response and (ii dynamic changes in expression of M. agalactiae surface variable proteins (Vpma, with multiple Vpma profiles co-existing in the same animal. In contrast and despite a sensitive model, none of the knock-out mutants were able to survive and colonize the host. The extreme avirulent phenotype of the two mutants was further supported by the absence of an IgG response in inoculated animals. The exact role of the NIF locus remains to be elucidated but these data demonstrate that it plays a key role in the infectious process of M. agalactiae and most likely of other pathogenic mycoplasma species as many carry closely related homologs.

  5. Setting objectives for managing Key deer

    Science.gov (United States)

    Diefenbach, Duane R.; Wagner, Tyler; Stauffer, Glenn E.

    2014-01-01

    The U.S. Fish and Wildlife Service (FWS) is responsible for the protection and management of Key deer (Odocoileus virginianus clavium) because the species is listed as Endangered under the Endangered Species Act (ESA). The purpose of the ESA is to protect and recover imperiled species and the ecosystems upon which they depend. There are a host of actions that could possibly be undertaken to recover the Key deer population, but without a clearly defined problem and stated objectives it can be difficult to compare and evaluate alternative actions. In addition, management goals and the acceptability of alternative management actions are inherently linked to stakeholders, who should be engaged throughout the process of developing a decision framework. The purpose of this project was to engage a representative group of stakeholders to develop a problem statement that captured the management problem the FWS must address with Key deer and identify objectives that, if met, would help solve the problem. In addition, the objectives were organized in a hierarchical manner (i.e., an objectives network) to show how they are linked, and measurable attributes were identified for each objective. We organized a group of people who represented stakeholders interested in and potentially affected by the management of Key deer. These stakeholders included individuals who represented local, state, and federal governments, non-governmental organizations, the general public, and local businesses. This stakeholder group met five full days over the course of an eight-week period to identify objectives that would address the following problem:“As recovery and removal from the Endangered Species list is the purpose of the Endangered Species Act, the U.S. Fish and Wildlife Service needs a management approach that will ensure a sustainable, viable, and healthy Key deer population. Urbanization has affected the behavior and population dynamics of the Key deer and the amount and characteristics

  6. Using Range-Wide Abundance Modeling to Identify Key Conservation Areas for the Micro-Endemic Bolson Tortoise (Gopherus flavomarginatus.

    Directory of Open Access Journals (Sweden)

    Cinthya A Ureña-Aranda

    Full Text Available A widespread biogeographic pattern in nature is that population abundance is not uniform across the geographic range of species: most occurrence sites have relatively low numbers, whereas a few places contain orders of magnitude more individuals. The Bolson tortoise Gopherus flavomarginatus is endemic to a small region of the Chihuahuan Desert in Mexico, where habitat deterioration threatens this species with extinction. In this study we combined field burrows counts and the approach for modeling species abundance based on calculating the distance to the niche centroid to obtain range-wide abundance estimates. For the Bolson tortoise, we found a robust, negative relationship between observed burrows abundance and distance to the niche centroid, with a predictive capacity of 71%. Based on these results we identified four priority areas for the conservation of this microendemic and threatened tortoise. We conclude that this approach may be a useful approximation for identifying key areas for sampling and conservation efforts in elusive and rare species.

  7. Policy issues in modern cartography

    CERN Document Server

    Taylor, DRF

    1998-01-01

    Policy Issues in Modern Cartography contains the views of national mapping agencies, legal scholars, the library community, the private sector and academia on these and many other important issues. The book begins with perspectives from national mapping agencies in Britain, Canada and the United States followed by a survey of the situation in Asia. The next three chapters deal primarily with legal issues such as copyright and intellectual property from both North American and European perspectives. Chapter 8 presents an important perspective on the key issues by a representative of the privat

  8. Muscle dysmorphia: methodological issues, implications for research.

    Science.gov (United States)

    Suffolk, Mark T; Dovey, Terence M; Goodwin, Huw; Meyer, Caroline

    2013-01-01

    Muscle dysmorphia is a male-dominated, body image-related psychological condition. Despite continued investigation, contention surrounds the nosological status of this disorder. The aim of this article was to review the literature on muscle dysmorphia to provide a qualitative account of methodological issues that may inhibit our understanding. Key areas relating to non-standardized participant groups, measuring instruments, and terminology were identified as potentially inhibiting symptom coherence and diagnostic reliability. New measuring instruments validated with clinical samples and carefully described participant groups, standardized terminology, and a greater emphasis on prospective longitudinal research with specific sub groups of the weight training community would be of interest to the field.

  9. Quality Issues Identified During the Evaluation of Biosimilars by the European Medicines Agency's Committee for Medicinal Products for Human Use.

    Science.gov (United States)

    Cilia, Mark; Ruiz, Sol; Richardson, Peter; Salmonson, Tomas; Serracino-Inglott, Anthony; Wirth, Francesca; Borg, John Joseph

    2018-02-01

    The aim of this study was to identify trends in deficiencies raised during the EU evaluation of the quality part of dossiers for marketing authorisation applications of biosimilar medicinal products. All adopted day 120 list of questions on the quality module of 22 marketing authorisation applications for biosimilars submitted to the European Medicines Agency and concluded by the end of October 2015 was analysed. Frequencies of common deficiencies identified were calculated and summarised descriptions included. Frequencies and trends on quality deficiencies were recorded and presented for 22 biosimilar applications. Thirty-two 'major objections' for 9 products were identified from 14 marketing authorisation applications with 15 raised for drug substance and 17 for drug product. In addition, 547 'other concerns' for drug substance and 495 for drug product were also adopted. The frequencies and trends of the identified deficiencies together with their impact were discussed from a regulatory perspective and how these impact key manufacturing processes and key materials used in the production of biosimilars. This study provides an insight to the regulatory challenges prospective companies need to consider when developing biosimilars; it also helps elucidate common pitfalls in the development and production of biosimilars and in the submission of dossiers for their marketing authorisations. The results are expected to be of interest to pharmaceutical companies but also to regulators to obtain consistent information on medicinal products based on transparent rules safeguarding the necessary pharmaceutical quality of medicinal products.

  10. The use of human factors methods to identify and mitigate safety issues in radiation therapy

    International Nuclear Information System (INIS)

    Chan, Alvita J.; Islam, Mohammad K.; Rosewall, Tara; Jaffray, David A.; Easty, Anthony C.; Cafazzo, Joseph A.

    2010-01-01

    Background and purpose: New radiation therapy technologies can enhance the quality of treatment and reduce error. However, the treatment process has become more complex, and radiation dose is not always delivered as intended. Using human factors methods, a radiotherapy treatment delivery process was evaluated, and a redesign was undertaken to determine the effect on system safety. Material and methods: An ethnographic field study and workflow analysis was conducted to identify human factors issues of the treatment delivery process. To address specific issues, components of the user interface were redesigned through a user-centered approach. Sixteen radiation therapy students were then used to experimentally evaluate the redesigned system through a usability test to determine the effectiveness in mitigating use errors. Results: According to findings from the usability test, the redesigned system successfully reduced the error rates of two common errors (p < .04 and p < .01). It also improved the mean task completion time by 5.5% (p < .02) and achieved a higher level of user satisfaction. Conclusions: These findings demonstrated the importance and benefits of applying human factors methods in the design of radiation therapy systems. Many other opportunities still exist to improve patient safety in this area using human factors methods.

  11. International co-operation. Key issue paper no. 6

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    In accordance with guidance provided by the Steering Group, this report assesses the adequacy and effectiveness of international co-operation relating to the nuclear fuel cycle, with a view toward identifying any needed new forms or arrangements for co-operation. In more specific terms, the Steering Committee`s guidance identified the following questions: Is the existing international framework sufficient for: the safe and secure operation of the fuel cycle; the economic and orderly development of the world`s nuclear energy systems (or their phase-out should this take place); international co-operation in R and D; international co-operation in industrial activities? Are there places where these requirements overlap or interact so as to impede activities which are desirable? Can new forms of co-operation be foreseen which would make it easier to implement any of the fuel cycle options in a safe, secure and responsible way? Are there other new forms of international co-operation which would affect the fuel cycle, e.g. regional institutions; international plutonium management regime and/or storage? Finally: What is the appropriate role of IAEA in any of these?.

  12. A research agenda for data and scale issues in Strategic Environmental Assessment (SEA)

    International Nuclear Information System (INIS)

    Joao, Elsa

    2007-01-01

    The way in which Strategic Environmental Assessment (SEA) succeeds in its key aim - to integrate the environment into strategic decision-making - is affected by the choice of both data and scale. The data and scale used within SEA fundamentally shape the process. However, in the past, these issues were often not discussed in an explicit or in-depth way. This article proposes a research agenda, and recommendations for future practice, on data and scale issues in SEA. Future research on data issues, spatial and temporal scales (both in terms of detail and extent), tiering, data quality and links to decision-making are recommended. The article concludes that questions of data and scale in SEA are not just technical, they are essential to identifying and understanding the issues that SEA should be addressing, and therefore are a core element of SEA

  13. CONSIDERATIONS ON THE METHODOLOGY FOR IDENTIFYING AND PRIORITIZING PUBLIC INVESTMENT PROJECTS IN ROMANIA

    OpenAIRE

    Tudor Nistorescu; Marilena Bogheanu

    2012-01-01

    The optimization of the investment project pipeline of public administration is a key issue for member states, including Romania, in the current European Union policy. Solving this problem depends largely on the establishment of an appropriate methodological framework for identifying and prioritizing projects and development programs. Based on the new requirements imposed by the European Commission for the next financial cycle 2014-2020, in this article we propose solutions for improving the ...

  14. E-Government: Initiatives, Developments, and Issues.

    Science.gov (United States)

    Aldrich, Duncan; Bertot, John Carlo; McClure, Charles R.

    2002-01-01

    Provides a background of government efforts to incorporate telecommunication and computer technologies to improve government performance and enhance citizen access to government information and services. Describes this symposium issue which discusses key issues that affect the success and implementation of electronic government initiatives. (LRW)

  15. The Causes of Poverty: Thinking Critically about a Key Economic Issue

    Science.gov (United States)

    Otlin, Josh

    2008-01-01

    Economics is a central part of civic education. Students need to know about the Constitution and the party system, but active citizenship in the twenty-first century requires much more than the standard civics courses offer. Economic issues dominate public policy debates ranging from Social Security to immigration to international security. If…

  16. Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

    Science.gov (United States)

    Teschke, Rolf; Eickhoff, Axel

    2015-01-01

    Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI) with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although, herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences) scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM) are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality.

  17. Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps

    Science.gov (United States)

    Teschke, Rolf; Eickhoff, Axel

    2015-01-01

    Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI) with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although, herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences) scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM) are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality. PMID:25954198

  18. Herbal hepatotoxicity in traditional and modern medicine: Actual key issues and new encouraging steps

    Directory of Open Access Journals (Sweden)

    Rolf eTeschke

    2015-04-01

    Full Text Available Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality.

  19. Critical technical issues and evaluation and comparison studies for inertial fusion energy reactors

    Energy Technology Data Exchange (ETDEWEB)

    Abdou, M.A. (Mechanical, Aerospace and Nuclear Engineering Dept., Univ. of California, Los Angeles, CA (United States)); Ying, A.Y. (Mechanical, Aerospace and Nuclear Engineering Dept., Univ. of California, Los Angeles, CA (United States)); Tillack, M.S. (Mechanical, Aerospace and Nuclear Engineering Dept., Univ. of California, Los Angeles, CA (United States)); Ghoniem, N.M. (Mechanical, Aerospace and Nuclear Engineering Dept., Univ. of California, Los Angeles, CA (United States)); Waganer, L.M. (McDonnell Douglas Aerospace, St. Louis, MI (United States)); Driemeyer, D.E. (McDonnell Douglas Aerospace, St. Louis, MI (United States)); Linford, G.J. (TRW Space and Electronics Div., Redondo Beach, CA (United States)); Drake, D.J.

    1994-01-01

    Two inertial fusion energy (IFE) reactor design concepts developed in the Prometheus studies were evaluated. Objectives were to identify and characterize critical issues and the R and D required to resolve them, and to establish a sound basis for future IFE technical and programmatic decisions. Each critical issue contains several key physics and engineering issues associated with major reactor components and impacts key aspects of feasibility, safety, and economic potential of IFE reactors. Generic critical issues center around: demonstration of moderate gain at low driver energy, feasibility of direct drive targets, feasibility of indirect drive targets for heavy ions, feasibility of indirect drive targets for lasers, cost reduction strategies for heavy ion drivers, demonstration of higher overall laser driver efficiency, tritium self-sufficiency in IFE reactors, cavity clearing at IFE pulse repetition rates, performance/reliability/lifetime of final laser optics, viability of liquid metal film for first wall protection, fabricability/reliability/lifetime of SiC composite structures, validation of radiation shielding requirements, design tools, and nuclear data, reliability and lifetime of laser and heavy ion drivers, demonstration of large-scale non-linear optical laser driver architecture, demonstration of cost effective KrF amplifiers, and demonstration of low cost, high volume target production techniques. Quantitative evaluation and comparison of the two design options have been made with special focus on physics feasibility, engineering feasibility, economics, safety and environment, and research and development (R and D) requirements. Two key conclusions are made based on the overall evaluation analysis. The heavy-ion driven reactors appear to have an overall advantage over laser-driven reactors.

  20. Pharmaceutical care issues identified by pharmacists in patients with diabetes, hypertension or hyperlipidaemia in primary care settings.

    Science.gov (United States)

    Chua, Siew Siang; Kok, Li Ching; Yusof, Faridah Aryani Md; Tang, Guang Hui; Lee, Shaun Wen Huey; Efendie, Benny; Paraidathathu, Thomas

    2012-11-12

    The roles of pharmacists have evolved from product oriented, dispensing of medications to more patient-focused services such as the provision of pharmaceutical care. Such pharmacy service is also becoming more widely practised in Malaysia but is not well documented. Therefore, this study is warranted to fill this information gap by identifying the types of pharmaceutical care issues (PCIs) encountered by primary care patients with diabetes mellitus, hypertension or hyperlipidaemia in Malaysia. This study was part of a large controlled trial that evaluated the outcomes of multiprofessional collaboration which involved medical general practitioners, pharmacists, dietitians and nurses in managing diabetes mellitus, hypertension and hyperlipidaemia in primary care settings. A total of 477 patients were recruited by 44 general practitioners in the Klang Valley. These patients were counselled by the various healthcare professionals and followed-up for 6 months. Of the 477 participants, 53.7% had at least one PCI, with a total of 706 PCIs. These included drug-use problems (33.3%), insufficient awareness and knowledge about disease condition and medication (20.4%), adverse drug reactions (15.6%), therapeutic failure (13.9%), drug-choice problems (9.5%) and dosing problems (3.4%). Non-adherence to medications topped the list of drug-use problems, followed by incorrect administration of medications. More than half of the PCIs (52%) were classified as probably clinically insignificant, 38.9% with minimal clinical significance, 8.9% as definitely clinically significant and could cause patient harm while one issue (0.2%) was classified as life threatening. The main causes of PCIs were deterioration of disease state which led to failure of therapy, and also presentation of new symptoms or indications. Of the 338 PCIs where changes were recommended by the pharmacist, 87.3% were carried out as recommended. This study demonstrates the importance of pharmacists working in

  1. Pharmaceutical care issues identified by pharmacists in patients with diabetes, hypertension or hyperlipidaemia in primary care settings

    Directory of Open Access Journals (Sweden)

    Chua Siew

    2012-11-01

    Full Text Available Abstract Background The roles of pharmacists have evolved from product oriented, dispensing of medications to more patient-focused services such as the provision of pharmaceutical care. Such pharmacy service is also becoming more widely practised in Malaysia but is not well documented. Therefore, this study is warranted to fill this information gap by identifying the types of pharmaceutical care issues (PCIs encountered by primary care patients with diabetes mellitus, hypertension or hyperlipidaemia in Malaysia. Methods This study was part of a large controlled trial that evaluated the outcomes of multiprofessional collaboration which involved medical general practitioners, pharmacists, dietitians and nurses in managing diabetes mellitus, hypertension and hyperlipidaemia in primary care settings. A total of 477 patients were recruited by 44 general practitioners in the Klang Valley. These patients were counselled by the various healthcare professionals and followed-up for 6 months. Results Of the 477 participants, 53.7% had at least one PCI, with a total of 706 PCIs. These included drug-use problems (33.3%, insufficient awareness and knowledge about disease condition and medication (20.4%, adverse drug reactions (15.6%, therapeutic failure (13.9%, drug-choice problems (9.5% and dosing problems (3.4%. Non-adherence to medications topped the list of drug-use problems, followed by incorrect administration of medications. More than half of the PCIs (52% were classified as probably clinically insignificant, 38.9% with minimal clinical significance, 8.9% as definitely clinically significant and could cause patient harm while one issue (0.2% was classified as life threatening. The main causes of PCIs were deterioration of disease state which led to failure of therapy, and also presentation of new symptoms or indications. Of the 338 PCIs where changes were recommended by the pharmacist, 87.3% were carried out as recommended. Conclusions This study

  2. International challenges and public policy issues.

    Science.gov (United States)

    Morris, N

    1999-01-01

    The paper presents an overview of current public policy issues relating to biological standardisation and control, drawing on the extensive background material assembled for two recent international reviews, and previously published work. It identifies a number of factors which are destabilising the current system and promoting a climate for change. These include the squeeze on public sector resources, the growth in volume and complexity of biologicals, developing world needs, concerns about harmonisation and new social and ethical issues. It is argued that this situation presents important opportunities for reviewing the existing boundaries between regulatory scientists, industry, and the public, for international agreement on priorities and for harmonisation and mutual recognition. While considerable progress has already been made on these issues at national, regional and global level, there is a need for fuller international participation and the additional impetus that would come from a higher-profile commitment by governments. Such commitment will also be important for the vital questions of sustaining the scientific base and securing the resource for an effective, truly worldwide programme of standardisation and control. An international approach will also be essential in steering biologicals control through the difficult social and ethical questions of the future. WHO, in collaboration with national authorities, has a key role to play in these developments.

  3. Identifying the Key Weaknesses in Network Security at Colleges.

    Science.gov (United States)

    Olsen, Florence

    2000-01-01

    A new study identifies and ranks the 10 security gaps responsible for most outsider attacks on college computer networks. The list is intended to help campus system administrators establish priorities as they work to increase security. One network security expert urges that institutions utilize multiple security layers. (DB)

  4. Environmental licensing issues for cogeneration plants

    International Nuclear Information System (INIS)

    Lipka, G.S.; Bibbo, R.V.

    1990-01-01

    The siting and licensing of cogeneration and independent power production (IPP) facilities is a complex process involving a number of interrelated engineering, economic, and environmental impact considerations. Important considerations for the siting and licensing of such facilities include air quality control and air quality impacts, water supply and wastewater disposal, and applicable noise criteria and noise impact considerations. Air quality control and air quality impact considerations for power generation facilities are commonly reviewed in the public forum, and most project developers are generally aware of the key air quality licensing issues. These issues include Best Available Control Technology (BACT) demonstration requirements, and air quality modeling requirements. BACT is a case-by-case determination, which causes uncertainty, in that developers have difficulty in projecting the cost of required control systems. Continuing developments in control technology may cause this problem to continue in the 1990's. Air quality modeling can be a problem in hilly terrain or within or near an urban environment, which could delay or preclude permitting of a new cogeneration or IPP facility in such locations. This paper discusses several environmental issues which are less frequently addressed than air quality issues, namely water/wastewater and noise. The design features of typical cogeneration and IPP facilities that affect water supply requirements, wastewater volumes, and noise emissions are discussed. Then, the site selection and impact review process are examined to identify typical constraints and trade-offs that can develop relative to water, wastewater, and noise issues. Trends in permit review requirements for water, wastewater, and noise are examined. Finally, innovative approaches that can be used to resolve potential development constraints for water, wastewater, and noise issues are discussed

  5. Special Issue Editorial

    African Journals Online (AJOL)

    While this special issue focuses on work in the South African context, ... practice) with youth addresses the key imperatives of (un)employment, age, ... patterns of male control over sexual encounters and women's sexuality are emergent ... in the paper by Ngabaza, Bojarczuk, Masuku and Roelfse, titled, 'Empowering young.

  6. Key Issues and Challenges in Estimating the Cost of Capital for Energy Network Utilities in Emerging Markets(Gelişmekte Olan Ülkelerde Enerji Şebeke Şirketleri İçin Sermaye Maliyetinin Tahminindeki Ana Konu ve Sorunlar

    Directory of Open Access Journals (Sweden)

    Mustafa GÖZEN

    2012-01-01

    Full Text Available Estimating the cost of capital in emerging markets presents greater difficulties because these markets have relatively illiquid capital markets and higher levels of sovereign risk, economic uncertainties, and political risks. Experience shows that in estimating cost of capital, energy regulators in emerging countries usually depend on the work and recommendations of their staff and/or outside consultancy services. Since the ultimate decision is made by regulators, they need to understand the challenges and key issues in estimating a fair and reasonable cost of capital for energy utilities. The article introduces and discusses the key issues and challenges that regulators have to deal with when estimating cost of capital. Unfortunately, there is no agreement among academics, regulators, bankers, and other practitioners on how to address the key issues and challenges in determining the cost of capital in emerging economies. This makes capital cost estimation even more difficult in emerging economies.

  7. Strategic Research for S&T Planning Should Focus on Key Issues

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Strategic planning for national and CAS mid- and long-term S&T development should avoid giving equal attention to every aspect of an issue, which can only lead to incremental progress.Instead, importance should be attached to priorities that will result in scientific, technical and engineering breakthroughs, said CAS President Lu Yongxiang, who is also vice-chairman of the national legislature, NPC.

  8. STUDY OF IDENTIFYING AND PRIORITIZING THE AFFECTING FACTORS ON BANK BRAND CUSTOMER LOYALTY

    OpenAIRE

    Zahra Aliyari; Yosef Beygzadeh

    2017-01-01

    Today, customer loyalty is the key to business success. By increased customers’ loyalty, market share and profitability level of enterprises will rise. Market perception along with planning and adopting appropriate strategies for making customers loyal and enhancing their rate of loyalty leads to long-term benefits for the enterprises. Given the importance of the issue, the goal of this study was to identify and prioritize the factors affecting loyalty to a banking brand from perspective of K...

  9. Framing the issues: moral distress in health care.

    Science.gov (United States)

    Pauly, Bernadette M; Varcoe, Colleen; Storch, Jan

    2012-03-01

    Moral distress in health care has been identified as a growing concern and a focus of research in nursing and health care for almost three decades. Researchers and theorists have argued that moral distress has both short and long-term consequences. Moral distress has implications for satisfaction, recruitment and retention of health care providers and implications for the delivery of safe and competent quality patient care. In over a decade of research on ethical practice, registered nurses and other health care practitioners have repeatedly identified moral distress as a concern and called for action. However, research and action on moral distress has been constrained by lack of conceptual clarity and theoretical confusion as to the meaning and underpinnings of moral distress. To further examine these issues and foster action on moral distress, three members of the University of Victoria/University of British Columbia (UVIC/UVIC) nursing ethics research team initiated the development and delivery of a multi-faceted and interdisciplinary symposium on Moral Distress with international experts, researchers, and practitioners. The goal of the symposium was to develop an agenda for action on moral distress in health care. We sought to develop a plan of action that would encompass recommendations for education, practice, research and policy. The papers in this special issue of HEC Forum arose from that symposium. In this first paper, we provide an introduction to moral distress; make explicit some of the challenges associated with theoretical and conceptual constructions of moral distress; and discuss the barriers to the development of research, education, and policy that could, if addressed, foster action on moral distress in health care practice. The following three papers were written by key international experts on moral distress, who explore in-depth the issues in three arenas: education, practice, research. In the fifth and last paper in the series, we highlight

  10. Managing the nation's high-level radioactive waste: key issues and recommendations

    International Nuclear Information System (INIS)

    1981-07-01

    To date, no unified national plan has been adopted to develop and implement a comprehensive system of management and disposal of high-level radioactive waste in the United States. Growing public concern about this problem has resulted in a number of recent efforts to develop a national high-level waste management policy. The 96th Congress strove to resolve the central issues, but ultimately failed to pass legislation, partly because of disagreements about the appropriate role of states in the siting of repositories for military waste. Outside government, a number of organizations convened representatives of diverse groups concerned with national high-level radioactive waste management to seek agreement on the major elements of national policy. One such organization was RESOLVE, Center for Environmental Conflict Resolution, which in May 1981 was merged into The Conservation Foundation. RESOLVE convened Forum II, a series of discussions among representatives of environmental, industrial, governmental, and citizen interest groups, in 1981 specifically to address the issues blocking Congressional agreement on high-level waste policy. This report contains the recommendations which resulted from these deliberations. Reprocessing, interim storage, respository development, and licensing requirements are addressed. Federal, state, and public participation in decision making are also discussed

  11. SARNET. Severe Accident Research Network - key issues in the area of source term

    International Nuclear Information System (INIS)

    Giordano, P.; Micaelli, J.C.; Haste, T.; Herranz, L.

    2005-01-01

    About fifty European organisations integrate in SARNET (Network of Excellence of the EU 6 th Framework Programme) their research capacities in resolve better the most important remaining uncertainties and safety issues concerning existing and future Nuclear Power Plants (NPPs) under hypothetical Severe Accident (SA) conditions. Wishing to maintain a long-lasting cooperation, they conduct three types of activities: integrating activities, spreading of excellence and jointly executed research. This paper summarises the main results obtained by the network after the first year, giving more prominence to those from jointly executed research in the Source Term area. Integrating activities have been performed through different means: the ASTEC integral computer code for severe accident transient modelling, through development of PSA2 methodologies, through the setting of a structure for definition of evolving R and D priorities and through the development of a web-network of data bases that hosts experimental data. Such activities have been facilitated by the development of an Advanced Communication Tool. Concerning spreading of excellence, educational courses covering Severe Accident Analysis Methodology and Level 2 PSA have been set up, to be given in early 2006. A detailed text book on Severe Accident Phenomenology has been designed and agreed amongst SARNET members. A mobility programme for students and young researchers is being developed, some detachments are already completed or in progress, and examples are quoted. Jointly executed research activities concern key issues grouped in the Corium, Containment and Source Term areas. In Source Term, behaviour of the highly radio-toxic ruthenium under oxidising conditions (like air ingress) for HBU and MOX fuel has been investigated. First modelling proposals for ASTEC have been made for oxidation of fuel and of ruthenium. Experiments on transport of highly volatile oxide ruthenium species have been performed. Reactor

  12. Sustainable Sourcing of Global Agricultural Raw Materials: Assessing Gaps in Key Impact and Vulnerability Issues and Indicators.

    Directory of Open Access Journals (Sweden)

    Nathaniel P Springer

    Full Text Available Understanding how to source agricultural raw materials sustainably is challenging in today's globalized food system given the variety of issues to be considered and the multitude of suggested indicators for representing these issues. Furthermore, stakeholders in the global food system both impact these issues and are themselves vulnerable to these issues, an important duality that is often implied but not explicitly described. The attention given to these issues and conceptual frameworks varies greatly--depending largely on the stakeholder perspective--as does the set of indicators developed to measure them. To better structure these complex relationships and assess any gaps, we collate a comprehensive list of sustainability issues and a database of sustainability indicators to represent them. To assure a breadth of inclusion, the issues are pulled from the following three perspectives: major global sustainability assessments, sustainability communications from global food companies, and conceptual frameworks of sustainable livelihoods from academic publications. These terms are integrated across perspectives using a common vocabulary, classified by their relevance to impacts and vulnerabilities, and categorized into groups by economic, environmental, physical, human, social, and political characteristics. These issues are then associated with over 2,000 sustainability indicators gathered from existing sources. A gap analysis is then performed to determine if particular issues and issue groups are over or underrepresented. This process results in 44 "integrated" issues--24 impact issues and 36 vulnerability issues--that are composed of 318 "component" issues. The gap analysis shows that although every integrated issue is mentioned at least 40% of the time across perspectives, no issue is mentioned more than 70% of the time. A few issues infrequently mentioned across perspectives also have relatively few indicators available to fully represent

  13. Sustainable Sourcing of Global Agricultural Raw Materials: Assessing Gaps in Key Impact and Vulnerability Issues and Indicators.

    Science.gov (United States)

    Springer, Nathaniel P; Garbach, Kelly; Guillozet, Kathleen; Haden, Van R; Hedao, Prashant; Hollander, Allan D; Huber, Patrick R; Ingersoll, Christina; Langner, Megan; Lipari, Genevieve; Mohammadi, Yaser; Musker, Ruthie; Piatto, Marina; Riggle, Courtney; Schweisguth, Melissa; Sin, Emily; Snider, Sara; Vidic, Nataša; White, Aubrey; Brodt, Sonja; Quinn, James F; Tomich, Thomas P

    2015-01-01

    Understanding how to source agricultural raw materials sustainably is challenging in today's globalized food system given the variety of issues to be considered and the multitude of suggested indicators for representing these issues. Furthermore, stakeholders in the global food system both impact these issues and are themselves vulnerable to these issues, an important duality that is often implied but not explicitly described. The attention given to these issues and conceptual frameworks varies greatly--depending largely on the stakeholder perspective--as does the set of indicators developed to measure them. To better structure these complex relationships and assess any gaps, we collate a comprehensive list of sustainability issues and a database of sustainability indicators to represent them. To assure a breadth of inclusion, the issues are pulled from the following three perspectives: major global sustainability assessments, sustainability communications from global food companies, and conceptual frameworks of sustainable livelihoods from academic publications. These terms are integrated across perspectives using a common vocabulary, classified by their relevance to impacts and vulnerabilities, and categorized into groups by economic, environmental, physical, human, social, and political characteristics. These issues are then associated with over 2,000 sustainability indicators gathered from existing sources. A gap analysis is then performed to determine if particular issues and issue groups are over or underrepresented. This process results in 44 "integrated" issues--24 impact issues and 36 vulnerability issues--that are composed of 318 "component" issues. The gap analysis shows that although every integrated issue is mentioned at least 40% of the time across perspectives, no issue is mentioned more than 70% of the time. A few issues infrequently mentioned across perspectives also have relatively few indicators available to fully represent them. Issues in the

  14. Systemic Thinking and Requisite Holism in Mastering Logistics Risks: the Model for Identifying Risks in Organisations and Supply Chain

    Directory of Open Access Journals (Sweden)

    Bojan Rosi

    2013-02-01

    Full Text Available Risks in logistic processes represent one of the major issues in supply chain management nowadays. Every organization strives for success, and uninterrupted operations are the key factors in achieving this goal, which cannot be achieved without efficient risk management. In the scope of supply chain risk research, we identified some key issues in the field, the major issue being the lack of standardization and models, which can make risk management in an organization easier and more efficient. Consequently, we developed a model, which captures and identifies risks in an organization and its supply chain. It is in accordance with the general risk management standard – ISO 31000, and incorporates some relevant recent findings from general and supply chain risk management, especially from the viewpoint of public segmentation. This experimental catalogue (which is also published online can serve as a checklist and a starting point of supply chain risk management in organizations. Its main idea is cooperation between experts from the area in order to compile an ever-growing list of possible risks and to provide an insight in the model and its value in practice, for which reason input and opinions of anyone who uses our model are greatly appreciated and included in the catalogue.

  15. Key Senators Issue Call for `Meaningful' Climate Legislation

    Science.gov (United States)

    Showstack, Randy

    With the U.S. Senate currently considering national energy legislation, Senators John McCain (R-Arizona) and Joseph Lieberman (D-Connecticut) plan to offer a modified version of their bipartisan, proposed Climate Stewardship Act of 2003 (S. 139) as an amendment. The amendment would establish a market driven system of greenhouse gas tradeable allowances to reduce emission. It would also provide for a program of scientific research on abrupt climate change in order to identify and understand past instances of abrupt change; and would establish a national greenhouse gas data base.

  16. Fatca and its key provisions and the issues of its application in Peru

    Directory of Open Access Journals (Sweden)

    Karen Sheppard Castillo

    2014-07-01

    Full Text Available As an answer to the international tax evasion problem, the U.S. Congress issued the Foreign Account Tax Compliance Act – Fatca. This Act aims to promote tax compliance among citizens and U.S. residents holding foreign bank accounts. To this effect, Fatca requires Foreign Financial Institutions to enter into an agreement with the Internal Revenue Service (IRS to provide the IRS information about the identity and the status of the bank accounts held by US persons. Entities not willing to enter into an agreement with the IRS will be subject to a 30% withholding on U.S. sourced income regardless of whether the income is tax exempt. The application of this Act in our country brings a lot of concern regarding some issues, such us extraterritoriality, bank secrecy, the application of civil and criminal law. Since the effective date of implementation of Fatca is July 1, 2014, we understand that an official opinion concerning these issues and the possibilityto enter into an Intergovernmental Agreement with the U.S. government will be forthcoming in the following months.

  17. Diabetes and end of life: ethical and methodological issues in gathering evidence to guide care.

    Science.gov (United States)

    Dunning, Trisha; Duggan, Nicole; Savage, Sally; Martin, Peter

    2013-03-01

    Providing palliative care for people with diabetes at the end of life is part of the chronic disease care trajectory, but end of life care is complex and the presence of diabetes further complicates management. The aim of the paper is to discuss the ethical and methodological issues encountered when undertaking research to develop guidelines for managing diabetes at the end of life and the strategies used to address the issues. The issues emerged as we developed guidelines for managing diabetes at the end of life, which included conducting individual interviews with 14 people with diabetes requiring palliative care and 10 family members. A reflexive researcher journal was maintained throughout the guideline development process. The interview transcripts and researcher's journal were analysed to determine key methodological, ethical and researcher-related issues. Key themes were vulnerability of the sampling population, methodological issues included recruiting participants and ensuring rigor, ethical issues concerned benefit and risk, justice, autonomy, privacy, professional boundaries and informed consent. Researcher-related issues were identified such as managing participant distress and their own emotional distress. People were willing to discuss end of life diabetes management preferences. Undertaking research with people at the end of life is complex because of their vulnerability and the ethical issues involved. However, the ethical principles of autonomy and justice apply and people should be given the relevant information and opportunity to decide whether to participate or not. © 2012 The Authors. Scandinavian Journal of Caring Sciences © 2012 Nordic College of Caring Science.

  18. Core message from PNC/H-3 and key issues for the next milestone

    International Nuclear Information System (INIS)

    Masuda, Sumio; Ishiguro, Katsuhiko; Yui, Mikazu; Mano, Tadashi

    1994-01-01

    The PNC/H-3 is the first progress report on the research and development of HLW geological disposal in Japan. This paper describes on overview of the performance assessment studies in the H-3 report and critical issues identified through the studies. Subsequently, the outline of the PNC's study plan for the post H-3 stage is introduced. The generic performance assessment studies in the H-3 report indicated that the performance of a massive engineered barrier system could be sufficient within a range of likely geological conditions in Japan. Sensitivity studies of the performance of the natural barrier system coupled with the strong engineered barrier indicated the importance of the investigation of geological barrier effects in the near-field. Studies in the H-3 indicated that the research approach which placed an emphasis on the near-field analyses was promising to confirm the technical feasibility of the HLW geologic disposal concept in Japan. In order to make the approach more promising and effective it is important to promote more detailed and comprehensive analyses of the near-field processes. The PNC's research and development of post H-3 stage before the year 2000 is focused on the detailed analyses of the near-field. A set of engineering scale laboratory experiments and in situ experiments at Tono and Kamaishi mines will play an important role for the post H-3 studies

  19. COMPETITIVENESS - KEY ISSUES OF THE ROMANIAN ECONOMY

    Directory of Open Access Journals (Sweden)

    Gabriela-Liliana, CIOBAN

    2014-11-01

    Full Text Available Based on the theory that competitiveness plays an increasingly powerful role in creating prosperity, wealth, a large number of economists, researchers, scientists, highlight a number of approaches aimed, on the one hand, on the analysis of competitiveness at national or regional level, and on the other hand, on the ability of local firms to achieve competitive products and to commercialize them in the extern markets. In this context we aim to analyze and develop strategies and methods to help identify competitive areas at a national level. This is necessary because in our opinion the competitiveness of a company and / or country is more than wealth itself; it means a systematic process of wealth creation, plus a social system in which most citizens have access to material wealth. We consider in this respect that a country cannot automatically be considered competitive only if it is rich in natural resources. In our view, a competitive country creates wealth through labor, talent and organization and thus it manages to have a productive and creative potential making it independent of material resources.

  20. Issues Raised in Relation to Radioactive Waste Management

    International Nuclear Information System (INIS)

    Atherton, Elizabeth

    2003-01-01

    Nirex has undertaken various consultations with different stakeholders to identify their issues and concerns about radioactive waste management in general and specific aspects of Nirex's work. This paper will outline what dialogue techniques Nirex has undertaken and the issues and concerns that people have raised during the events. It will outline some of the work that Nirex is undertaking to address stakeholders' issues and concerns. Nirex has used a variety of dialogue techniques co-ordinated under the Nirex Involvement Programme to engage with stakeholders about the work we undertake. We are now trying to address the issues, concerns, scenarios and questions raised in our work programme. Key lessons that we have learned in undertaking the dialogues include: The importance of appropriate facilitation and organisation of meetings; The need for a clear purpose for meetings; Being flexible to the needs of the attendees and the issues they raise; Providing feedback to those who participate and following up issues. Through engaging with the public Nirex has learned that: Radioactive waste is not an everyday concern for people; The public can, will and want to engage with the issue of radioactive waste management. This includes engaging with the ethical debate. To facilitate this Nirex and others need to: Provide information in a neutral form outlining the pros and cons and including various people's opinions; Use proactive techniques to allow access and space for people to discuss the issues; Demonstrate how people's opinions have been taken into account. People understand the issues very differently to the way institutions understand them. There is a need for institutions to learn to understand public concerns and the ways in which the public understand issues, as well as for the public to understand the institutional positions better. We are using these insights to develop our future work in this area

  1. Development of safety-related regulatory requirements for nuclear power in developing countries. Key issue paper no. 4

    International Nuclear Information System (INIS)

    Han, K.I.

    2000-01-01

    In implementing a national nuclear power program, balanced regulatory requirements are necessary to ensure nuclear safety and cost competitive nuclear power, and to help gain public acceptance. However, this is difficult due to the technology-intensive nature of the nuclear regulatory requirements, the need to reflect evolving technology and the need for cooperation among multidisciplinary technical groups. This paper suggests approaches to development of balanced nuclear regulatory requirements in developing countries related to nuclear power plant safety, radiation protection and radioactive waste management along with key technical regulatory issues. It does not deal with economic or market regulation of electric utilities using nuclear power. It suggests that national regulatory requirements be developed using IAEA safety recommendations as guidelines and safety requirements of the supplier country as a main reference after careful planning, manpower buildup and thorough study of international and supplier country's regulations. Regulation making is not recommended before experienced manpower has been accumulated. With an option that the supplier country's regulations may be used in the interim, the lack of complete national regulatory requirements should not deter introduction of nuclear power in developing countries. (author)

  2. Identifying key factors and strategies for reducing industrial CO2 emissions from a non-Kyoto protocol member's (Taiwan) perspective

    International Nuclear Information System (INIS)

    Lin, Sue J.; Lu, I.J.; Lewis, Charles

    2006-01-01

    In this study we use Divisia index approach to identify key factors affecting CO 2 emission changes of industrial sectors in Taiwan. The changes of CO 2 emission are decomposed into emission coefficient, energy intensity, industrial structure and economic growth. Furthermore, comparisons with USA, Japan, Germany, the Netherlands and South Korea are made to have a better understanding of emission tendency in these countries and to help formulate our CO 2 reduction strategies for responding to the international calls for CO 2 cuts. The results show that economic growth and high energy intensity were two key factors for the rapid increase of industrial CO 2 emission in Taiwan, while adjustment of industrial structure was the main component for the decrease. Although economic development is important, Taiwan must keep pace with the international trends for CO 2 reduction. Among the most important strategies are continuous efforts to improve energy intensity, fuel mix toward lower carbon, setting targets for industrial CO 2 cuts, and advancing green technology through technology transfer. Also, the clean development mechanism (CDM) is expected to play an important role in the future

  3. Image encryption using fingerprint as key based on phase retrieval algorithm and public key cryptography

    Science.gov (United States)

    Zhao, Tieyu; Ran, Qiwen; Yuan, Lin; Chi, Yingying; Ma, Jing

    2015-09-01

    In this paper, a novel image encryption system with fingerprint used as a secret key is proposed based on the phase retrieval algorithm and RSA public key algorithm. In the system, the encryption keys include the fingerprint and the public key of RSA algorithm, while the decryption keys are the fingerprint and the private key of RSA algorithm. If the users share the fingerprint, then the system will meet the basic agreement of asymmetric cryptography. The system is also applicable for the information authentication. The fingerprint as secret key is used in both the encryption and decryption processes so that the receiver can identify the authenticity of the ciphertext by using the fingerprint in decryption process. Finally, the simulation results show the validity of the encryption scheme and the high robustness against attacks based on the phase retrieval technique.

  4. A perspective of some key issues related to the evolution of safeguards, the state level and regional concepts

    International Nuclear Information System (INIS)

    Fernandez Moreno, S.

    2013-01-01

    This presentation is focused on the implementation of safeguards at present and the directions that they could be taken in the future. There are some key questions to be answered in the implementation of international safeguards that are aimed at helping to determine more clearly what safeguards will be more effective and efficient under the so called 'state-level concept' (SLC). A first and important step is to agree on a definition and scope of the SLC and to determine how the IAEA and relevant States could achieve a smooth transition from the historic criteria based safeguards systems to a new one based on the SLC that would be more flexible, but yet technically oriented and non-discriminatory. A second issue is to fully reflect on the factors that are influencing safeguards developments and that impact on their future shape. Some suggestions about enhancing safeguard implementation at present and in the future include first: a fresh look to the approach to safeguards cooperation: the IAEA has to revisit its activities to assist states in establishing good SSAC (State Systems of Accounting and Control), and secondly: investigating and promoting the development of concepts and technologies to share its verification capabilities with states and regional organizations. Another key consideration to the future of safeguards is the people. Adequate staff and the existence of appropriate training and education in safeguards are very important considerations to ensure effective and professional safeguards. Highly technically qualified staff in nuclear sciences is vital to build competence in safeguards in states, the IAEA, and regional organizations. The paper is followed by the slides of the presentation. (authors)

  5. Development of a framework for identification of political environmental issues faced by multinational hotel chains in newly industrialized countries in Asia

    OpenAIRE

    Kim, Chol Yong

    1992-01-01

    The primary/objective of this study was to develop a framework for identification of political environmental issues faced by multinational hotel chains in newly industrialized countries in Asia. To accomplish the objective, key factors having an impact upon these hotel chains were identified using the Delphi Technique.

  6. A Cross-Continental Study on Children's Drawings of Football Players: Implications for Understanding Key Issues and Controversies in Human Figure Drawings.

    Science.gov (United States)

    Baluch, Bahman; Duffy, Linda J; Badami, Rokhsareh; Pereira, Elisangela C Ap

    2017-08-01

    Professionals examine various aspects of girls' and boys' drawings as a way of understanding their intelligence, personality and emotional state. However, the extent to which such measures could be universally generalised or attributed to a specific cultural norm is still a debatable issue. In the present study five key features of children's drawings namely: the size (height) of the drawings, profile or full face, figure in action or static, shaded or non-shaded and the nature of additional details were examined from a cross-cultural perspective, and by providing a topic (football) for which children's drawing of a human figure could provide opportunities for the latter indices to manifest and flourish. Children from three countries; England, Iran and Brazil, representing three continents took part in this study. The participants were asked to draw a football player from their own country and from the other participating countries. The results showed that Brazilian children differ from Iranian and English children by drawing significantly smaller figures and putting more football action in the drawings. Shading of the figure drawn was more prevalent amongst English children. Such findings have implications for the interpretation of key aspects of children's drawings in educational, clinical and therapeutic settings and from a universal vs. culturally-specific viewpoint.

  7. A Cross-Continental Study on Children's Drawings of Football Players: Implications for Understanding Key Issues and Controversies in Human Figure Drawings

    Science.gov (United States)

    Baluch, Bahman; Duffy, Linda J.; Badami, Rokhsareh; Pereira, Elisangela C. Ap

    2017-01-01

    Professionals examine various aspects of girls’ and boys’ drawings as a way of understanding their intelligence, personality and emotional state. However, the extent to which such measures could be universally generalised or attributed to a specific cultural norm is still a debatable issue. In the present study five key features of children’s drawings namely: the size (height) of the drawings, profile or full face, figure in action or static, shaded or non-shaded and the nature of additional details were examined from a cross-cultural perspective, and by providing a topic (football) for which children’s drawing of a human figure could provide opportunities for the latter indices to manifest and flourish. Children from three countries; England, Iran and Brazil, representing three continents took part in this study. The participants were asked to draw a football player from their own country and from the other participating countries. The results showed that Brazilian children differ from Iranian and English children by drawing significantly smaller figures and putting more football action in the drawings. Shading of the figure drawn was more prevalent amongst English children. Such findings have implications for the interpretation of key aspects of children's drawings in educational, clinical and therapeutic settings and from a universal vs. culturally-specific viewpoint. PMID:28904595

  8. PHARMACOTHERAPY OF THE DIGESTIVE DISEASES AMONG TEENAGERS. CURRENT STATE OF THE ISSUE

    Directory of Open Access Journals (Sweden)

    E.A. Vishneva

    2009-01-01

    Full Text Available Deterioration of the children's health, especially as long as they study in school is one of the key issues today. The article highlights the results of the «Healthy school» program implementation, which was developed by the «Quality of life» charity fund involving Solvay Pharma. Much attention was paid to the pharmacoepidemiological study of the digestive diseases among teenagers — conformance evaluation of the given nosology pharmacotherapy at the outpatient stage to the existing standards of the evidence based medicine. The researcher described in detail nonconformances to the generally accepted recommendations identified during the study — nonprescription and/or unjustified application of the medications. They also provided the structure of the enzymatic drugs application.Key words: pharmacoepidemiology, gastrointestinal disturbances, pharmacotherapy, children.

  9. Policymakers' Reflections on Water Governance Issues

    Directory of Open Access Journals (Sweden)

    Joyeeta Gupta

    2013-03-01

    Full Text Available The two cultures theory argues that policy makers and scientists have different cultures and difficulty in communicating with each other. Others argue that there is increasing co-production of knowledge. This essay aims to assess the concerns of policy makers based on our policy work, policy-related research work, and our day-to-day experiences in terms of three questions: What are the perceived major issues for water governance? What are the major challenges in the structure of the existing global water governance approach? What is the vision for improving global water governance? This essay combines views from governmental, hybrid, inter- and non-governmental policy makers. It argues that water covers so many issues, aspects, and sectors that a key challenge is whether water should be governed as a sector or as a cross-cutting issue. It looks at how this challenge plays out within the United Nations system and leads to specific goal setting, while missing an overall visionary approach and a legally binding system of governance; within the hybrid arena, where it leads to inclusive discussion but not necessarily triggering consensus decisions; within nation states, where it has led to a loss of focus and a multitude of gaps and overlaps; and within transnational cooperative projects, where it has led to multiple interpretations of what is good practice. It then identifies a series of research questions.

  10. Experimental aspects of deterministic secure quantum key distribution

    Energy Technology Data Exchange (ETDEWEB)

    Walenta, Nino; Korn, Dietmar; Puhlmann, Dirk; Felbinger, Timo; Hoffmann, Holger; Ostermeyer, Martin [Universitaet Potsdam (Germany). Institut fuer Physik; Bostroem, Kim [Universitaet Muenster (Germany)

    2008-07-01

    Most common protocols for quantum key distribution (QKD) use non-deterministic algorithms to establish a shared key. But deterministic implementations can allow for higher net key transfer rates and eavesdropping detection rates. The Ping-Pong coding scheme by Bostroem and Felbinger[1] employs deterministic information encoding in entangled states with its characteristic quantum channel from Bob to Alice and back to Bob. Based on a table-top implementation of this protocol with polarization-entangled photons fundamental advantages as well as practical issues like transmission losses, photon storage and requirements for progress towards longer transmission distances are discussed and compared to non-deterministic protocols. Modifications of common protocols towards a deterministic quantum key distribution are addressed.

  11. Identifying Twitter influencer profiles for health promotion in Saudi Arabia.

    Science.gov (United States)

    Albalawi, Yousef; Sixsmith, Jane

    2017-06-01

    New media platforms, such as Twitter, provide the ideal opportunity to positively influence the health of large audiences. Saudi Arabia has one of the highest number of Twitter users of any country, some of whom are very influential in setting agendas and contributing to the dissemination of ideas. Those opinion leaders, both individuals and organizations, influential in the new media environment have the potential to raise awareness of health issues, advocate for health and potentially instigate change at a social level. To realize the potential of the new media platforms for public health, the function of opinion leaders is key. This study aims to identify and profile the most influential Twitter accounts in Saudi Arabia. Multiple measures, including: number of followers and four influence scores, were used to evaluate Twitter accounts. The data were then filtered and analysed using ratio and percentage calculations to identify the most influential users. In total, 99 Saudi Twitter accounts were classified, resulting in the identification of 25 religious men/women, 16 traditional media, 14 sports related, 10 new media, 6 political, 6 company and 4 health accounts. The methods used to identify the key influential Saudi accounts can be applied to inform profile development of Twitter users in other countries. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Market Makers' Recognition of Key Success Factors in Electronic Marketplaces

    Directory of Open Access Journals (Sweden)

    Rosemary Stockdale

    2003-05-01

    Full Text Available This study examines the recognition and use of critical success factors by market makers in electronic marketplaces. A content analysis of e-marketplace websites enabled an examination of how these factors have been incorporated into marketplace sites. Evidence of market makers’ awareness of the success factors was found in all the sites although there remain questions and issues to be addressed. Awareness of the need for critical mass and privacy were very evident, but the key factors of security, technological infrastructure and neutrality were identified as areas of concern. Evidence of an awareness of the importance of trust by market makers was found, but more effective signalling of trust to buyers and sellers within the marketplaces is required.

  13. Key issues in the outlook for minerals and energy

    International Nuclear Information System (INIS)

    Waring, T.; Love, G.; Hogan, J.; Gooday, P.

    1996-01-01

    The outlook for Australia's minerals and energy sector continues to be positive because of the flow-on effects of economic growth in the newly industrialized Asia. The East Asian share of mineral and energy commodities continues to expand reflecting the growing demand for consumer goods and new economic and social infrastructure. Uncertainties in the minerals and energy outlook include the future economic performance of the developed countries and the former Soviet Union, trade and environmental issues and the effects of changing technology on minerals and energy production and consumption. Encouraged by good prospects for exploration success and firmer markets, real exploration expenditure is forecast to continue to rise and the volume of Australian mine production is expected to rise by 14 percent between 1995-6 and 2000-1. Export earnings from mineral and energy commodities are expected to rise by $5.6 billion Australian (16 percent) from 1995-6 levels to reach $41.9 billion in real terms by 2000-1. (author). 2 tabs., 14 figs., 14 refs

  14. Exploring the key predictors of retention in emergency nurses.

    Science.gov (United States)

    Sawatzky, Jo-Ann V; Enns, Carol L

    2012-07-01

    To explore the factors that predict the retention of nurses working in emergency departments. The escalating shortage of nurses is one of the most critical issues facing specialty areas, such as the emergency department. Therefore, it is important to identify the key influencing and intermediary factors that affect emergency department nurses' intention to leave. As part of a larger study, a cross-sectional survey was completed by 261 registered nurses working in the 12 designated emergency departments within rural, urban community and tertiary hospitals in Manitoba, Canada. Twenty-six per cent of the respondents will probably/definitely leave their current emergency department jobs within the next year. Engagement was the key predictor of intention to leave (P burnout (P nursing management, professional practice, collaboration with physicians, staffing resources and shift work emerged as significant influencing factors for engagement. Engagement plays a central role in emergency department nurses intention to leave. Addressing the factors that influence engagement may reduce emergency department nurses' intention to leave. This study highlights the value of research-based evidence as the foundation for developing innovative strategies for the retention of emergency department nurses. © 2012 Blackwell Publishing Ltd.

  15. A brief review of revocable ID-based public key cryptosystem

    Directory of Open Access Journals (Sweden)

    Tsu-Yang Wu

    2016-03-01

    Full Text Available The design of ID-based cryptography has received much attention from researchers. However, how to revoke the misbehaviour/compromised user in ID-based public key cryptosystem becomes an important research issue. Recently, Tseng and Tsai proposed a novel public key cryptosystem called revocable ID-based public key cryptosystem (RIBE to solve the revocation problem. Later on, numerous research papers based on the Tseng-Tsai key RIBE were proposed. In this paper, we brief review Tseng and Tsai's RIBE. We hope this review can help the readers to understand the Tseng and Tsai's revocable ID-based public key cryptosystem.

  16. Coherent one-way quantum key distribution

    Science.gov (United States)

    Stucki, Damien; Fasel, Sylvain; Gisin, Nicolas; Thoma, Yann; Zbinden, Hugo

    2007-05-01

    Quantum Key Distribution (QKD) consists in the exchange of a secrete key between two distant points [1]. Even if quantum key distribution systems exist and commercial systems are reaching the market [2], there are still improvements to be made: simplify the construction of the system; increase the secret key rate. To this end, we present a new protocol for QKD tailored to work with weak coherent pulses and at high bit rates [3]. The advantages of this system are that the setup is experimentally simple and it is tolerant to reduced interference visibility and to photon number splitting attacks, thus resulting in a high efficiency in terms of distilled secret bits per qubit. After having successfully tested the feasibility of the system [3], we are currently developing a fully integrated and automated prototype within the SECOQC project [4]. We present the latest results using the prototype. We also discuss the issue of the photon detection, which still remains the bottleneck for QKD.

  17. Overview of the Health and Retirement Study and Introduction to the Special Issue.

    Science.gov (United States)

    Fisher, Gwenith G; Ryan, Lindsay H

    2018-01-01

    Twenty five years ago, the largest academic behavioral and social science project ever undertaken in the U.S. began: the Health and Retirement Study (HRS). The HRS is an invaluable publicly available dataset for investigating work, aging, and retirement and informing public policy on these issues. This biennial longitudinal study began in 1992 and has studied more than 43,000 individuals and produced almost 4000 journal articles, dissertations, books, book chapters, and reports to date. The purpose of this special issue of Work, Aging and Retirement is to describe the HRS and highlight relevant research that utilizes this rich and complex dataset. First, we briefly describe the background that led to the development of the HRS. Then we summarize key aspects of the study, including its development, sampling, and methodology. Our review of the content of the survey focuses on the aspects of the study most relevant to research on worker aging and retirement. Next, we identify key strengths and important limitations of the study and provide advice to current and future HRS data users. Finally, we summarize the articles in this Special Issue (all of which use data from the HRS) and how they advance our knowledge and understanding of worker aging and retirement.

  18. Justification of radiographic examinations: What are the key issues?

    Science.gov (United States)

    Vom, Jason; Williams, Imelda

    2017-09-01

    Justification of radiographic examinations is the practice of evaluating requested radiological examinations to assess for clinical merit and appropriateness based on clinical notes and patient information. This implies that justification in radiography requires the evaluation of requested examinations, the justification of exposures being applied and determining whether patients fit the recommended criteria for the procedure. Medico-legal requirements by the professional registration body, the Medical Radiation Practice Board of Australia (MRPBA), identify justification as an advocated and obligatory practice for radiographers. Yet, justification remains an inconsistent practice implemented amongst Australian radiographers. This review aims to identify associated barriers inhibiting the consistent practice of justification and the hesitance by radiographers in practicing justification responsibilities. It also recommends a change in workplace culture which encourages radiographers to accept a more autonomous role that cultivates critical thinking, reflection and research-informed decision making as justification will ultimately benefit patients. © 2017 The Authors. Journal of Medical Radiation Sciences published by John Wiley & Sons Australia, Ltd on behalf of Australian Society of Medical Imaging and Radiation Therapy and New Zealand Institute of Medical Radiation Technology.

  19. Exploiting genomic data to identify proteins involved in abalone reproduction.

    Science.gov (United States)

    Mendoza-Porras, Omar; Botwright, Natasha A; McWilliam, Sean M; Cook, Mathew T; Harris, James O; Wijffels, Gene; Colgrave, Michelle L

    2014-08-28

    Aside from their critical role in reproduction, abalone gonads serve as an indicator of sexual maturity and energy balance, two key considerations for effective abalone culture. Temperate abalone farmers face issues with tank restocking with highly marketable abalone owing to inefficient spawning induction methods. The identification of key proteins in sexually mature abalone will serve as the foundation for a greater understanding of reproductive biology. Addressing this knowledge gap is the first step towards improving abalone aquaculture methods. Proteomic profiling of female and male gonads of greenlip abalone, Haliotis laevigata, was undertaken using liquid chromatography-mass spectrometry. Owing to the incomplete nature of abalone protein databases, in addition to searching against two publicly available databases, a custom database comprising genomic data was used. Overall, 162 and 110 proteins were identified in females and males respectively with 40 proteins common to both sexes. For proteins involved in sexual maturation, sperm and egg structure, motility, acrosomal reaction and fertilization, 23 were identified only in females, 18 only in males and 6 were common. Gene ontology analysis revealed clear differences between the female and male protein profiles reflecting a higher rate of protein synthesis in the ovary and higher metabolic activity in the testis. A comprehensive mass spectrometry-based analysis was performed to profile the abalone gonad proteome providing the foundation for future studies of reproduction in abalone. Key proteins involved in both reproduction and energy balance were identified. Genomic resources were utilised to build a database of molluscan proteins yielding >60% more protein identifications than in a standard workflow employing public protein databases. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Evidence of the Possible Harm of Endocrine-Disrupting Chemicals in Humans: Ongoing Debates and Key Issues

    Directory of Open Access Journals (Sweden)

    Duk-Hee Lee

    2018-03-01

    Full Text Available Evidence has emerged that endocrine-disrupting chemicals (EDCs can produce adverse effects, even at low doses that are assumed safe. However, systemic reviews and meta-analyses focusing on human studies, especially of EDCs with short half-lives, have demonstrated inconsistent results. Epidemiological studies have insuperable methodological limitations, including the unpredictable net effects of mixtures, non-monotonic dose-response relationships, the non-existence of unexposed groups, and the low reliability of exposure assessment. Thus, despite increases in EDC-linked diseases, traditional epidemiological studies based on individual measurements of EDCs in bio-specimens may fail to provide consistent results. The exposome has been suggested as a promising approach to address the uncertainties surrounding human studies, but it is never free from these methodological issues. Although exposure to EDCs during critical developmental periods is a major concern, continuous exposure to EDCs during non-critical periods is also harmful. Indeed, the evolutionary aspects of epigenetic programming triggered by EDCs during development should be considered because it is a key mechanism for developmental plasticity. Presently, living without EDCs is impossible due to their omnipresence. Importantly, there are lifestyles which can increase the excretion of EDCs or mitigate their harmful effects through the activation of mitohormesis or xenohormesis. Effectiveness of lifestyle interventions should be evaluated as practical ways against EDCs in the real world.

  1. Tritium retention in candidate next-step protection materials: engineering key issues and research requirements

    International Nuclear Information System (INIS)

    Federici, G.; Andrew, P.L.; Wu, C.H.

    1995-01-01

    Although a considerable volume of valuable data on the behaviour of tritium in beryllium and carbon-based armours exposed to hydrogenic fusion plasmas has been compiled over the past years both from operation of present-day tokamaks and from laboratory simulations, knowledge is far from complete and tritium inventory predictions for these materials remain highly uncertain. In this paper we elucidate the main mechanisms responsible for tritium trapping and release in next-step D-T tokamaks, as well as the applicability of some of the presently known data bases for design purposes. Owing to their strong anticipated implications on tritium uptake and release, attention is focused mainly on the interaction of tritium with neutron damage induced defects, on tritium codeposition with eroded carbon and on the effects of oxide and surface contaminants. Some preliminary quantitative estimates are presented based on most recent experimental findings and latest modelling developments as well. The influence of important working conditions such as target temperature, loading particle fluxes, erosion and redeposition rates, as well as material characteristics such as the type of morphology of the protection material (i.e. amorphous plasma-sprayed beryllium vs. solid forms), and design dependent parameters are discussed in this paper. Remaining issues which require additional effort are identified. (orig.)

  2. Identifying key nodes in multilayer networks based on tensor decomposition.

    Science.gov (United States)

    Wang, Dingjie; Wang, Haitao; Zou, Xiufen

    2017-06-01

    The identification of essential agents in multilayer networks characterized by different types of interactions is a crucial and challenging topic, one that is essential for understanding the topological structure and dynamic processes of multilayer networks. In this paper, we use the fourth-order tensor to represent multilayer networks and propose a novel method to identify essential nodes based on CANDECOMP/PARAFAC (CP) tensor decomposition, referred to as the EDCPTD centrality. This method is based on the perspective of multilayer networked structures, which integrate the information of edges among nodes and links between different layers to quantify the importance of nodes in multilayer networks. Three real-world multilayer biological networks are used to evaluate the performance of the EDCPTD centrality. The bar chart and ROC curves of these multilayer networks indicate that the proposed approach is a good alternative index to identify real important nodes. Meanwhile, by comparing the behavior of both the proposed method and the aggregated single-layer methods, we demonstrate that neglecting the multiple relationships between nodes may lead to incorrect identification of the most versatile nodes. Furthermore, the Gene Ontology functional annotation demonstrates that the identified top nodes based on the proposed approach play a significant role in many vital biological processes. Finally, we have implemented many centrality methods of multilayer networks (including our method and the published methods) and created a visual software based on the MATLAB GUI, called ENMNFinder, which can be used by other researchers.

  3. International Policy Framework for Protecting Critical Information Infrastructure: A Discussion Paper Outlining Key Policy Issues

    NARCIS (Netherlands)

    Brown, B.; Goetz, E.; Verhoest, P.; Helmus, S.; Luiijf, H.A.M.; Bruce, R.; Dynes, S.; Brechbuhl, H.

    2005-01-01

    Cyber security is a uniquely challenging policy issue with a wide range of public and private stakeholders within countries and beyond national boundaries. This executive summary and the full discussion paper delineate the need on a high priority basis to address cyber security issues and develop an

  4. Procedures for identifying evidence-based psychological treatments for older adults.

    Science.gov (United States)

    Yon, Adriana; Scogin, Forrest

    2007-03-01

    The authors describe the methods used to identify evidence-based psychological treatments for older adults in this contribution to the special section. Coding teams were assembled to review the literature on several problems relevant to mental health and aging. These teams used the manual developed by the Committee on Science and Practice of the Society for Clinical Psychology (Division 12) of the American Psychological Association that provided definitions of key constructs used in coding. The authors provide an overview of the process followed by the review teams and of some of the issues that emerged to illustrate the steps involved in the coding procedure. Identifying evidence-based treatments is a fundamental aspect of promoting evidence-based practice with older adults; such practice is advocated by most health care disciplines, including psychology. ((c) 2007 APA, all rights reserved).

  5. Competence development: Key issues and trends in European competence policies

    DEFF Research Database (Denmark)

    Milana, Marcella

      In recent years there has been a rising political attention on competence development both at national and international level. At European level in particular, since 2000, with the set of the Lisbon Agenda, different bodies representing the Union have been very productive in generating working...... papers, reports, and communications that led to directives and resolutions concerning the development and recognition of skills and competences in a lifelong learning perspective. In 2005 this process led to the definition of a European Framework on Key Competences for Lifelong Learning - covering those...... competences that are given priority within the Union - as well as a European Qualification Framework, a reference tool for making qualifications - here described in terms of progressive levels of competence - transparent and transferable within the European borders. The aim of the paper is to investigate...

  6. Identifying key performance indicators in food technology contract R&D

    NARCIS (Netherlands)

    Flipse, S.M.; Sanden, van der M.C.A.; Velden, van der T.; Fortuin, F.T.J.M.; Omta, S.W.F.; Osseweijer, P.

    2013-01-01

    Innovating companies increasingly rely on outsourcing to Contract Research Organisations (CROs) for their Research and Development (R&D), which are largely understudied. This paper presents the outcome of a case study in the field of food technology contract research, identifying context

  7. Development of cross border gas transmission projects raise challenging issues. Case studies: The transmed and the Maghreb/Europe pipelines

    International Nuclear Information System (INIS)

    Khene, D.

    1997-01-01

    Development of cross border gas transmission projects raise complex and interdependent issues whose successful resolution require not only technical and management strengths but also a close cooperation between the key players involved in the game. In this paper we shall attempt to explain some of the major issues encountered during the appraisal and construction of long distance gas pipeline schemes. The information used derive essentially from the experience gained during the development of the Trans-mediterranean and the Maghreb/Europe pipelines. Running through the various issues we shall also identify and then discuss a number of factors which contributed to the successful implementation of these two projects. (au)

  8. A bio-inspired methodology of identifying influential nodes in complex networks.

    Directory of Open Access Journals (Sweden)

    Cai Gao

    Full Text Available How to identify influential nodes is a key issue in complex networks. The degree centrality is simple, but is incapable to reflect the global characteristics of networks. Betweenness centrality and closeness centrality do not consider the location of nodes in the networks, and semi-local centrality, leaderRank and pageRank approaches can be only applied in unweighted networks. In this paper, a bio-inspired centrality measure model is proposed, which combines the Physarum centrality with the K-shell index obtained by K-shell decomposition analysis, to identify influential nodes in weighted networks. Then, we use the Susceptible-Infected (SI model to evaluate the performance. Examples and applications are given to demonstrate the adaptivity and efficiency of the proposed method. In addition, the results are compared with existing methods.

  9. Factoring RSA keys from certified smart cards : Coppersmith in the wild

    NARCIS (Netherlands)

    Bernstein, D.J.; Chang, Y.A.; Cheng, C.M.; Chou, L.P.; Heninger, N.; Lange, T.; Someren, van N.

    2013-01-01

    An attacker can efficiently factor at least 184 distinct 1024-bit RSA keys from Taiwan's national "Citizen Digital Certificate" database. The big story here is that these keys were generated by government-issued smart cards that were certified secure. The certificates had all the usual buzzwords:

  10. Key issues of multiple access technique for LEO satellite communication systems

    Institute of Scientific and Technical Information of China (English)

    温萍萍; 顾学迈

    2004-01-01

    The large carrier frequency shift caused by the high-speed movement of satellite (Doppler effects) and the propagation delay on the up-down link are very critical issues in an LEO satellite communication system, which affects both the selection and the implementation of a suitable access method. A Doppler based multiple access technique is used here to control the flow and an MPRMA-HS protocol is proposed for the application in LEO satellite communication systems. The extended simulation trials prove that the proposed scheme seems to be a very promising access method.

  11. Dopamine signaling and myopia development: What are the key challenges.

    Science.gov (United States)

    Zhou, Xiangtian; Pardue, Machelle T; Iuvone, P Michael; Qu, Jia

    2017-11-01

    In the face of an "epidemic" increase in myopia over the last decades and myopia prevalence predicted to reach 2.5 billion people by the end of this decade, there is an urgent need to develop effective and safe therapeutic interventions to slow down this "myopia booming" and prevent myopia-related complications and vision loss. Dopamine (DA) is an important neurotransmitter in the retina and mediates diverse functions including retina development, visual signaling, and refractive development. Inspired by the convergence of epidemiological and animal studies in support of the inverse relationship between outdoor activity and risk of developing myopia and by the close biological relationship between light exposure and dopamine release/signaling, we felt it is timely and important to critically review the role of DA in myopia development. This review will revisit several key points of evidence for and against DA mediating light control of myopia: 1) the causal role of extracellular retinal DA levels, 2) the mechanism and action of dopamine D1 and D2 receptors and 3) the roles of cellular/circuit retinal pathways. We examine the experiments that show causation by altering DA, DA receptors and visual pathways using pharmacological, transgenic, or visual environment approaches. Furthermore, we critically evaluate the safety issues of a DA-based treatment strategy and some approaches to address these issues. The review identifies the key questions and challenges in translating basic knowledge on DA signaling and myopia from animal studies into effective pharmacological treatments for myopia in children. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  12. Flammable gas issues in double-contained receiver tanks. Revision 1

    International Nuclear Information System (INIS)

    Peurrung, L.M.; Mahoney, L.A.; Stewart, C.W.; Gauglitz, P.A.; Pederson, L.R.; Bryan, S.A.; Shepard, C.L.

    1998-06-01

    Four double-contained receiver tanks (DCRTs) at Hanford will be used to store salt-well pumped liquids from tanks on the Flammable Gas Watch List. This document was created to serve as a technical basis or reference document for flammable gas issues in DCRTs. The document identifies, describes, evaluates, and attempts to quantify potential gas carryover and release mechanisms. It estimates several key parameters needed for these calculations, such as initial aqueous concentrations and ventilation rate, and evaluates the uncertainty in those estimates. It justifies the use of the Schumpe model for estimating vapor-liquid equilibrium constants. It identifies several potential waste compatibility issues (such as mixing and pH or temperature changes) that could lead to gas release and provides a basis for calculating their effects. It evaluates the potential for gas retention in precipitated solids within a DCRT and whether retention could lead to a buoyant displacement instability (rollover) event. It discusses rates of radiolytic, thermal, and corrosive hydrogen generation within the DCRT. It also describes in detail the accepted method of calculating the lower flammability limit (LFL) for mixtures of flammable gases

  13. Flammable gas issues in double-contained receiver tanks. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Peurrung, L.M.; Mahoney, L.A.; Stewart, C.W.; Gauglitz, P.A.; Pederson, L.R.; Bryan, S.A.; Shepard, C.L.

    1998-06-01

    Four double-contained receiver tanks (DCRTs) at Hanford will be used to store salt-well pumped liquids from tanks on the Flammable Gas Watch List. This document was created to serve as a technical basis or reference document for flammable gas issues in DCRTs. The document identifies, describes, evaluates, and attempts to quantify potential gas carryover and release mechanisms. It estimates several key parameters needed for these calculations, such as initial aqueous concentrations and ventilation rate, and evaluates the uncertainty in those estimates. It justifies the use of the Schumpe model for estimating vapor-liquid equilibrium constants. It identifies several potential waste compatibility issues (such as mixing and pH or temperature changes) that could lead to gas release and provides a basis for calculating their effects. It evaluates the potential for gas retention in precipitated solids within a DCRT and whether retention could lead to a buoyant displacement instability (rollover) event. It discusses rates of radiolytic, thermal, and corrosive hydrogen generation within the DCRT. It also describes in detail the accepted method of calculating the lower flammability limit (LFL) for mixtures of flammable gases.

  14. Strategic environmental noise mapping: methodological issues concerning the implementation of the EU Environmental Noise Directive and their policy implications.

    LENUS (Irish Health Repository)

    Murphy, E

    2010-04-01

    This paper explores methodological issues and policy implications concerning the implementation of the EU Environmental Noise Directive (END) across Member States. Methodologically, the paper focuses on two key thematic issues relevant to the Directive: (1) calculation methods and (2) mapping methods. For (1), the paper focuses, in particular, on how differing calculation methods influence noise prediction results as well as the value of the EU noise indicator L(den) and its associated implications for comparability of noise data across EU states. With regard to (2), emphasis is placed on identifying the issues affecting strategic noise mapping, estimating population exposure, noise action planning and dissemination of noise mapping results to the general public. The implication of these issues for future environmental noise policy is also examined.

  15. Investigation of gamma-ray fingerprint identifying mechanism for the types of radiation sources

    CERN Document Server

    Liu Su Ping; Gu Dang Chang; Gong-Jian; Hao Fan Hua; Hu Guang Chun

    2002-01-01

    Radiation fingerprints sometimes can be used to label and identify the radiation resources. For instance, in a future nuclear reduction treaty that requires verification of irreversible dismantling of reduced nuclear warheads, the radiation fingerprints of nuclear warheads are expected to play a key role in labelling and identifying the reduced warheads. It would promote the development of nuclear warheads deep-cuts verification technologies if authors start right now some investigations on the issues related to the radiation fingerprints. The author dedicated to the investigation of gamma-ray fingerprint identifying mechanism for the types of radiation resources. The purpose of the identifying mechanism investigation is to find a credible way to tell whether any two gamma-ray spectral fingerprints that are under comparison are radiated from the same resource. The authors created the spectrum pattern comparison (SPC) to study the comparability of the two radiation fingerprints. Guided by the principle of SPC,...

  16. Public Key Encryption Supporting Plaintext Equality Test and User-Specified Authorization

    NARCIS (Netherlands)

    Tang, Qiang

    2011-01-01

    In this paper we investigate a category of public key encryption schemes which supports plaintext equality test and user-specified authorization. With this new primitive, two users, who possess their own public/private key pairs, can issue token(s) to a proxy to authorize it to perform plaintext

  17. Governance of Technical Education in India : Key Issues, Principles, and Case Studies

    OpenAIRE

    Blom, Andreas; Cheong, Jannette

    2010-01-01

    Tertiary education, and in particular technical and engineering education, is critical to India's aspirations of strengthening its reputation as a major competitive player in the Global knowledge economy. The system is huge and complex, and there is a consensus that reforms are imperative. Issues of fair access and affordable participation in higher education are critical if India is to em...

  18. Liberia’s Post-War Development: Key Issues and U.S. Assistance

    Science.gov (United States)

    2010-05-25

    GNI) total: $634.4 million (2008) GNI per capita: $170 (2008) External debt: $1.7 billion (2010 ) Key exports: Rubber, timber, iron, cocoa , gold...for killers whose purpose is to remove various body organs for uses, including consumption , in traditional occult ceremonies that participants...accountability in relation to the extraction of timber, oil and gas, cocoa and other natural resources, including by strengthening implementation and monitoring

  19. Review on technical issues influencing the performance of chemical barriers of TRU waste repository

    International Nuclear Information System (INIS)

    Fujita, Tomonari; Sugiyama, Daisuke; Tsukamoto, Masaki; Yokoyama, Hayaichi

    1997-01-01

    Studies of technical issues influencing the performance assessment of TRU waste disposal which is occurred from the nuclear fuel reprocessing were reviewed in related to the development of safety analysis method. Especially, the chemical containment was investigated as a key barrier to radionuclide migration. TRU waste including long-lived radionuclides need long-term performance assessment which could be assumed only by the chemical barrier. The description of technical issues concerned with the performance of TRU waste repository has been divided into the following categories: long-term degradation of cementitious materials as engineered barrier for radionuclide migration, effect of colloids, organic macromolecules and organic degradation products on chemical behavior of radionuclides, gas generation by corrosion of metallic wastes, and effects of microbial activity. Preliminary performance assessment indicated that important factors affecting performance of chemical barriers in near-field were the distribution coefficient and the solubility of radionuclides in near-field groundwater. Therefore, it was identified that key issues associated with performance of chemical barrier were evaluation of (a) the long-term change of distribution coefficient of cementitious material through the degradation under repository condition and (b) chemical speciation change of radionuclides such as increase of solubility by the presence of colloidal-size materials. (author)

  20. Identifying the gaps in Nepalese migrant workers' health and well-being: a review of the literature.

    Science.gov (United States)

    Simkhada, Padam P; Regmi, Pramod R; van Teijlingen, Edwin; Aryal, Nirmal

    2017-07-01

    The health and well-being of migrant workers from low-income countries is often neglected in travel medicine. This article uses Nepal as a case study to highlight key issues affecting this particular group of international travellers. This narrative review used a comprehensive systematic literature search to identify relevant studies on Nepal. The included articles were thematically analysed leading to four key themes or risk factors. The search found 18 articles from which we identified 3 key themes related directly to migrant workers: (1) sexual risk taking; (2) occupational health and (3) lifestyles, and a fourth theme related to partners and family of migrant workers who are left behind in Nepal. Of the 18 included articles, 11 articles discussed sexual risk taking and HIV, whilst considerably fewer focused on work-related risk factors and lifestyle factors in migrant workers. Migrant workers who are generally healthy appear to be similar to tourist travellers in regarding sexual health as a key issue related to being abroad. Risky sexual behaviour increases in individuals separated from their usual sexual partners, away from their own communities and families, leading to the so-called 'situational disinhibition'. Considering the recent media coverage of deaths and injuries among migrant workers in the Middle East, it is interesting to see that their sexual health is more prevalent in the research literature. This article argues that travel medicine should provide more emphasis to the health and well-being of migrant workers as a highly vulnerable group of travellers with additional impact on the health of those left behind. © International Society of Travel Medicine, 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  1. In-Silico Integration Approach to Identify a Key miRNA Regulating a Gene Network in Aggressive Prostate Cancer

    Science.gov (United States)

    Colaprico, Antonio; Bontempi, Gianluca; Castiglioni, Isabella

    2018-01-01

    Like other cancer diseases, prostate cancer (PC) is caused by the accumulation of genetic alterations in the cells that drives malignant growth. These alterations are revealed by gene profiling and copy number alteration (CNA) analysis. Moreover, recent evidence suggests that also microRNAs have an important role in PC development. Despite efforts to profile PC, the alterations (gene, CNA, and miRNA) and biological processes that correlate with disease development and progression remain partially elusive. Many gene signatures proposed as diagnostic or prognostic tools in cancer poorly overlap. The identification of co-expressed genes, that are functionally related, can identify a core network of genes associated with PC with a better reproducibility. By combining different approaches, including the integration of mRNA expression profiles, CNAs, and miRNA expression levels, we identified a gene signature of four genes overlapping with other published gene signatures and able to distinguish, in silico, high Gleason-scored PC from normal human tissue, which was further enriched to 19 genes by gene co-expression analysis. From the analysis of miRNAs possibly regulating this network, we found that hsa-miR-153 was highly connected to the genes in the network. Our results identify a four-gene signature with diagnostic and prognostic value in PC and suggest an interesting gene network that could play a key regulatory role in PC development and progression. Furthermore, hsa-miR-153, controlling this network, could be a potential biomarker for theranostics in high Gleason-scored PC. PMID:29562723

  2. Key-space analysis of double random phase encryption technique

    Science.gov (United States)

    Monaghan, David S.; Gopinathan, Unnikrishnan; Naughton, Thomas J.; Sheridan, John T.

    2007-09-01

    We perform a numerical analysis on the double random phase encryption/decryption technique. The key-space of an encryption technique is the set of possible keys that can be used to encode data using that technique. In the case of a strong encryption scheme, many keys must be tried in any brute-force attack on that technique. Traditionally, designers of optical image encryption systems demonstrate only how a small number of arbitrary keys cannot decrypt a chosen encrypted image in their system. However, this type of demonstration does not discuss the properties of the key-space nor refute the feasibility of an efficient brute-force attack. To clarify these issues we present a key-space analysis of the technique. For a range of problem instances we plot the distribution of decryption errors in the key-space indicating the lack of feasibility of a simple brute-force attack.

  3. Issues in contracting with small minority businesses

    Energy Technology Data Exchange (ETDEWEB)

    Wood, M.T.; Radford, M.L.; Saari, L.M.; Wright, J.

    1986-04-01

    The focus of this investigation was to identify issues central to increasing the involvement of small minority businesses (MBs) in federal or prime contracts with the Department of Energy (DOE), as a foundation for designing a program to assist buyers of contracted goods and services. The approach to determining issues involved interviewing the owners of 15 MBs, representing a range of businesses, and buyers and purchasing officers from three large DOE prime contractors. The interviewees identified issues related to positive working relationships and rated a predetermined set of 27 potential MB-DOE problems regarding their existence and criticalness. The issues identified by MBs were of two broad types. The predominant issues and barriers were associated with their being small businesses. Secondary issues reflected the disadvantaged status of the business (woman and/or minority-owned).

  4. Biometric Identifiers and Border Security: 9/11 Commission Recommendations and Related Issues

    National Research Council Canada - National Science Library

    Morgan, Daniel; Krouse, William

    2005-01-01

    .... This report provides an overview of biometric technologies and the major U.S. biometric border screening systems, including US-VISIT, and discusses issues such as cost, performance, and user acceptance...

  5. Ethical issues in laryngology: tracheal stenting as palliative care.

    Science.gov (United States)

    Kazi, Aasif A; Flowers, W Jeffrey; Barrett, Jeanna M; O'Rourke, Ashli K; Postma, Gregory N; Weinberger, Paul M

    2014-07-01

    To improve understanding of aspects of end-of-life care that may not be intuitive to the otolaryngology community. A comprehensive review of the literature was performed by searching Medline, Embase, and Google Scholar databases. Primary manuscripts' bibliographies were reviewed to identify any nonindexed references. Prospective consultation by means of one-on-one interviews was sought from nonotolaryngology key stakeholders in the areas of hospice nursing care and patient advocacy in order to identify pertinent issues. We identified over 1,000 articles published from 1965 to 2013 on the topic of tracheal stents, as well as over 40,000 on hospice/end-of-life care. Three articles focusing specifically on palliative care and airway stenting were identified, of which three were case reports and none were definitive reviews. There are a number of significant issues and concepts unique to hospice care. These are likely unfamiliar to all except for head and neck oncology-specialized otolaryngologists. An example is that hospice care focuses on quality of life rather than prolongation of life (such as curative surgery). Patients with nonoperable tracheal obstruction from malignancy face an unpleasant demise from suffocation. For those patients, stenting can relieve suffering by restoring airway patency. Airway stenting can be a valid palliative care option, even for terminal patients receiving hospice care, when performed to relieve airway obstruction and improve quality of life. End-of-life ethics is an underdeveloped area of otolaryngology that should be explored. © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

  6. Biomass sustainability criteria: Greenhouse gas accounting issues for biogas and biomethane facilities

    International Nuclear Information System (INIS)

    Adams, P.W.R.; Mezzullo, W.G.; McManus, M.C.

    2015-01-01

    Biomass sustainability criteria were introduced in the UK following the EU Renewable Energy Directive. Criteria are now applicable to solid biomass and biogas, however because it is not mandatory criteria can be adapted by member states with the risk of different interpretation. Operators are required to report greenhouse gas (GHG) emissions for every MJ of energy produced. This paper provides a rigorous analysis of the current GHG emissions accounting methodology for biogas facilities to assess expected compliance for producers. This research uses data from operating CHP and biomethane facilities to calculate GHG emissions using the existing methodology and Government calculator. Results show that whilst many biogas facilities will meet GHG thresholds, as presently defined by Government, several operators may not comply due to methodological uncertainties and chosen operating practices. Several GHG accounting issues are identified which need to be addressed so the biogas industry achieves its reporting obligations and is represented objectively with other bioenergy technologies. Significant methodological issues are highlighted; including consignment definition, mass balance allocation, measurement of fugitive methane emissions, accounting for digestate co-products, fossil fuel comparators, and other accounting problems. Recommendations are made to help address the GHG accounting issues for policy makers and the biogas industry. - Highlights: • GHG accounting issues identified that affect potential compliance with legislation. • Appropriate recognition of digestate value is a key issue for biogas industry. • Fugitive methane emissions measurement is critical for sustainability criteria. • Chosen fossil fuel comparator value determines the potential GHG saving. • Rigorous analysis of GHG accounting methodology for biogas and biomethane systems.

  7. The Data Issue: Opportunities and Challenges for Scientific Publishers

    Science.gov (United States)

    Murphy, F.; Irving, D. H.

    2011-12-01

    Using the recent report for the 'Opportunities in Data Exchange' Project produced by - and for - researchers, libraries/data centres and publishers (and which is based on a broad range of studies, questionnaires and evidence) we have defined current practices and expectations, and the gaps and dilemmas involved in producing data and datasets, and then analysed their relationship to formal publications. As a result, we identified potential opportunities to evolve scientific insights to be more useful and re-useful: with consequent implications for custodianship and long-term data management. We also defined a number of key incentives and barriers towards achieving these objectives. As a case study, the earth and environmental sciences have come under particularly close scrutiny with respect to data-ownership and -sharing arrangements, sometimes with damaging results to the discipline's reputation. These issues, along with considerable technological challenges, have to be handled effectively in order to best support all the users along the data chain. To that end, we show that key stakeholders - among them scientific publishers - need to have a clear idea of how to progress data-intensive derived information, which we demonstrate is often not the case. Towards bridging this knowledge gap, we have compiled a roadmap of next steps and key issues to be acknowledged and addressed by the scientific publishing community. These include: engaging directly with researchers, policy-makers, funding bodies and direct competitors to build innovative partnerships and enhance impact; providing technological and training investment and developing alongside the emerging discipline of 'data scientist': the 'data publisher'. This individual/company will need to combine a close understanding of researchers' priorities, together with market, legal and technical opportunities and restrictions.

  8. Key issues in space nuclear power challenges for the future

    Science.gov (United States)

    Brandhorst, Henry W., Jr.

    1991-01-01

    The future appears rich in missions that will extend the frontiers of knowledge, human presence in space, and opportunities for profitable commerce. Key to the success of these ventures is the availability of plentiful, cost effective electric power and assured, low cost access to space. While forecasts of space power needs are problematic, an assessment of future needs based on terrestrial experience has been made. These needs fall into three broad categories: survival, self sufficiency, and industrialization. The cost of delivering payloads to orbital locations from LEO to Mars has been determined and future launch cost reductions projected. From these factors, then, projections of the performance necessary for future solar and nuclear space power options has been made. These goals are largely dependent upon orbital location and energy storage needs. Finally the cost of present space power systems has been determined and projections made for future systems.

  9. [Full attention to several key issues in surgical treatment for the elderly patients with gastrointestinal cancer].

    Science.gov (United States)

    Zhu, Zhenggang

    2016-05-01

    With the development of population aging in our country, the incidence of gastrointestinal cancer is increasing. The risk of developing gastrointestinal cancer in elderly over 75 years was 5-6 times and the risk of death of gastrointestinal cancer was 7-8 times of the general population. As compared to non-elderly, the incidence of gastric cancer was not decreased obviously but the total incidence of colorectal cancer was increased more quickly. Therefore, screening of gastrointestinal cancer should be performed in the elderly for early discovery, diagnosis and treatment. Because of the insidious onset of the illness in elderly patients, gastrointestinal cancers are mostly diagnosed at advanced or late stage (stage III or IV). Well differentiated cancer is more common, such as papillary or tubular adenocarcinoma. Lauren type, Borrmann II or III are more common in gastric cancer, which are relatively favorable. Compared with non-elderly patients, many elderly patients also suffer from comorbid diseases with higher operation risk and postoperative complication rates. Therefore, we must pay great attention to the perioperative management and the surgical operation for the elderly patients. In this paper, several key issues involved the development trend of incidence and mortality of gastrointestinal cancer, the clinicopathological characteristics, the comorbidity and surgical treatment in the elderly patients with gastrointestinal cancer will be elaborated, aiming at promoting further attention to the clinical therapeutic strategies, management measures and prognostic factors for the elderly patients with gastrointestinal cancer.

  10. Safety and Regulatory Issues of the Thorium Fuel Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Ade, Brian [ORNL; Worrall, Andrew [ORNL; Powers, Jeffrey [ORNL; Bowman, Steve [ORNL; Flanagan, George [ORNL; Gehin, Jess [ORNL

    2014-02-01

    Thorium has been widely considered an alternative to uranium fuel because of its relatively large natural abundance and its ability to breed fissile fuel (233U) from natural thorium (232Th). Possible scenarios for using thorium in the nuclear fuel cycle include use in different nuclear reactor types (light water, high temperature gas cooled, fast spectrum sodium, molten salt, etc.), advanced accelerator-driven systems, or even fission-fusion hybrid systems. The most likely near-term application of thorium in the United States is in currently operating light water reactors (LWRs). This use is primarily based on concepts that mix thorium with uranium (UO2 + ThO2), add fertile thorium (ThO2) fuel pins to LWR fuel assemblies, or use mixed plutonium and thorium (PuO2 + ThO2) fuel assemblies. The addition of thorium to currently operating LWRs would result in a number of different phenomenological impacts on the nuclear fuel. Thorium and its irradiation products have nuclear characteristics that are different from those of uranium. In addition, ThO2, alone or mixed with UO2 fuel, leads to different chemical and physical properties of the fuel. These aspects are key to reactor safety-related issues. The primary objectives of this report are to summarize historical, current, and proposed uses of thorium in nuclear reactors; provide some important properties of thorium fuel; perform qualitative and quantitative evaluations of both in-reactor and out-of-reactor safety issues and requirements specific to a thorium-based fuel cycle for current LWR reactor designs; and identify key knowledge gaps and technical issues that need to be addressed for the licensing of thorium LWR fuel in the United States.

  11. Identification of Key Indicators for Sustainable Construction Materials

    Directory of Open Access Journals (Sweden)

    Humphrey Danso

    2018-01-01

    Full Text Available Studies on sustainable construction materials are on the rise with their environmental, social, and economic benefits. This study identifies the key indicators for measuring sustainable construction materials. The design used for the study was that of a survey which relied on a questionnaire with five-point Likert scale to generate data for the analysis. For this purpose, 25 indicators from the three dimensions (environmental, social, and economic identified from the literature were presented to the respondents in a structured questionnaire, and responses were collected and analysed using SPSS. The study identified three key environmental indicators for measuring sustainable construction materials, and these indicators are human toxicity, climate change, and solid waste. Furthermore, adaptability, thermal comfort, local resources, and housing for all were identified as the four key social indicators for sustainable construction materials. In addition, maintenance cost, operational cost, initial cost, long-term savings, and life span were found to be the five key economic indicators for measuring sustainable construction materials. The study therefore suggests that these twelve indicators should be considered in future studies that seek to measure sustainable construction materials.

  12. Czech teachers’ attitudes toward typical characteristics of intellectually gifted learners with dyslexia and the issue of identifying and educating them

    Directory of Open Access Journals (Sweden)

    Šárka Portešová

    2010-06-01

    Full Text Available The presented study deals with the issue of basic school teachers’ attitudestowards selected behavioral and cognitive characteristics of intellectually gifted lear-ners with dyslexia and the issue of identifying and educating these learners. Researchis being conducted at the time as a Greek-Czech intercultural study. However, in thepresented contribution only Czech research data are analyzed and interpreted. In theresearch, we used Attitudes Toward Giftedness/Learning disability – Dyslexia Scale byGreek authors Gari, Panagiota, Nikolopoulou (2006. This method was administeredto 158 teachers from all over the Czech Republic. Based on statistical analysis, thepresented empirical examination reached some important conclusions. It became clearthat Czech teachers are good at identifying characteristics related to manifestations ofa “gifted learner” and a “learner with a learning disability”. Moreover, they are able toidentify also the so-called duality in learning abilities, i.e. the simultaneousness of abi-lity and handicap in the learning process manifested in a particular cognitive domain.However, they identify this duality especially within Czech language. The most proble-matic appears to be the accepting of the existence of this typical characteristic of thegiven population of learners in other academic subjects, for example in mathematics.It is here in particular where teachers tend to expect nothing but exceptional perfor-mance, without a possibility of partial failure (they derive it from giftedness. It seemsthat due to the refusal of the existence of duality in learning ability intervening in allacademic subjects, it can lead to a wrong identification of this minority group of thegifted. Nevertheless, this fact must be confirmed in further empiric research.

  13. Identifying Communication Barriers to Colorectal Cancer Screening Adherence among Appalachian Kentuckians.

    Science.gov (United States)

    Bachman, Audrey Smith; Cohen, Elisia L; Collins, Tom; Hatcher, Jennifer; Crosby, Richard; Vanderpool, Robin C

    2017-08-18

    Utilizing data from 40 in-depth interviews, this article identifies both barriers and facilitators to colorectal screening guideline adherence among Appalachian Kentucky adults recruited through a community-based research network. Key findings identify (a) varying levels of knowledge about screening guidelines, (b) reticence to engage in screening processes, and (c) nuanced communication with healthcare providers and family members regarding screening adherence. What participants knew about the screening process was often derived from personal stories or recalled stories from family members about their screening experiences. Reticence to engage in screening processes reflected reports of cumbersome preparation, privacy issues, embarrassment, medical mistrust, fear of receiving a cancer diagnosis, and lack of symptoms. Participants cited many ways to enhance patient-centered communication, and the findings from this study have implications for health communication message design and communication strategies for healthcare practices in Appalachian Kentucky clinics.

  14. Key Topics in Sports Medicine

    OpenAIRE

    2006-01-01

    Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1) Sports injuries, rehabilitation and injury prevention, 2) Exercise physiology, fitness testing and training, 3) Drugs in sport, 4) Exercise and health promotion, 5) Sport and exercise for special and clinical populations, 6) The ps...

  15. CONTEMPORARY AFRICAN PHILOSOPHY: EMERGENT ISSUES ...

    African Journals Online (AJOL)

    Dean SPGS NAU

    another on meta-philosophical issues about African philosophy, their successors, in ... Key Words: African identity, hermeneutics and culture, ... Even the quest to overcome the hegemony of Western ..... African philosophers to rethink the principles, concepts, attitudes ... there is a certain openness to new possibilities at the.

  16. Current issues and actions

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the progress that has been made toward achieving full regulatory compliance at the Hanford Site. Ongoing compliance self-assessments, implementation of the Tri-Party Agreement, and public meetings continue to identify environmental compliance issues. These issues are discussed openly with the regulatory agencies and with the public to ensure that all environmental compliance issues are addressed.

  17. Current issues and actions

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the progress that has been made toward achieving full regulatory compliance at the Hanford Site. Ongoing compliance self-assessments, implementation of the Tri-Party Agreement, and public meetings continue to identify environmental compliance issues. These issues are discussed openly with the regulatory agencies and with the public to ensure that all environmental compliance issues are addressed

  18. Interim report on the assessment of engineering issues for compact high-field ignition devices

    International Nuclear Information System (INIS)

    Flanagan, C.A.

    1986-04-01

    The engineering issues addressed at the workshop included the overall configuration, layout, and assembly; limiter and first-wall energy removal; magnet system structure design; fabricability; repairability; and costs. In performing the assessment, the primary features and characteristics of each concept under study were reviewed as representative of this class of ignition device. The emphasis was to understand the key engineering areas of concern for this class of device and deliberately not attempt to define an optimum design or to choose a best approach. The assessment concluded that compact ignition tokamaks, as represented by the three concepts under study, are feasible. A number of critical engineering issues were identified, and all appear to have tractable solutions. The engineering issues appear quite challenging, and to obtain increased confidence in the apparent design solutions requires completion of the next level of design detail, complemented by appropriate development programs and testing

  19. The Human Rights Key: An innovative tool for teaching health and ...

    African Journals Online (AJOL)

    I propose the Human Rights Key as a useful visual communication tool to guide students in connecting their classroom learning with the reality of local, regional and international health and human rights issues. As an OER with a Creative Commons licence, the Key is available online for both educators and students to use ...

  20. Present status and environmental implications of the different fuel cycles. Key issue paper no. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    For decades plutonium has been a key focus of international discussions of both non-proliferation and the future of the nuclear fuel cycle. This paper is intended to address the management of separated plutonium in the civil fuel cycle in the near term - until 2015 - describing both the technologies employed and the policies of key countries. This paper also addresses technology and policy for the management of weapons plutonium being declared excess to defence needs. Refs, figs, tabs.

  1. Producer responsibility for e-waste management: key issues for consideration - learning from the Swiss experience.

    Science.gov (United States)

    Khetriwal, Deepali Sinha; Kraeuchi, Philipp; Widmer, Rolf

    2009-01-01

    E-waste, a relatively recent addition to the waste stream in the form of discarded electronic and electric equipment, is getting increasing attention from policy makers as the quantity being generated is rising rapidly. One of the most promising policy options to address this issue is to extend the producers responsibility for their products beyond the point of sale, until end-of-product-life. This paper briefly introduces the concept of extended producer responsibility (EPR) and its applicability in the area of the end-of-life management of electronic and electrical equipment (EEE). It then examines the decade-long experience of Switzerland in using EPR to manage its e-waste, elaborating on the experience of the Swiss system in overcoming specific issues, and finally wrapping up with a synopsis of the lessons for policy makers. We consider each issue as an enquiry of questions confronting a policy maker and the choices that may present themselves. The five issues discussed are: (i) the challenges in getting an EPR based system started; (ii) securing financing to ensure a self-sustaining and smooth functioning system; (iii) organising a logistics network for the take back and collection of the e-waste; (iv) ensuring compliance of the various actors involved; and finally (v) reducing the threat of monopolistic practices.

  2. Strategic environmental noise mapping: methodological issues concerning the implementation of the EU Environmental Noise Directive and their policy implications.

    Science.gov (United States)

    Murphy, E; King, E A

    2010-04-01

    This paper explores methodological issues and policy implications concerning the implementation of the EU Environmental Noise Directive (END) across Member States. Methodologically, the paper focuses on two key thematic issues relevant to the Directive: (1) calculation methods and (2) mapping methods. For (1), the paper focuses, in particular, on how differing calculation methods influence noise prediction results as well as the value of the EU noise indicator L(den) and its associated implications for comparability of noise data across EU states. With regard to (2), emphasis is placed on identifying the issues affecting strategic noise mapping, estimating population exposure, noise action planning and dissemination of noise mapping results to the general public. The implication of these issues for future environmental noise policy is also examined. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  3. Natural gas 1998: Issues and trends

    International Nuclear Information System (INIS)

    1999-06-01

    Natural Gas 1998: Issues and Trends provides a summary of the latest data and information relating to the US natural gas industry, including prices, production, transmission, consumption, and the financial and environmental aspects of the industry. The report consists of seven chapters and five appendices. Chapter 1 presents a summary of various data trends and key issues in today's natural gas industry and examines some of the emerging trends. Chapters 2 through 7 focus on specific areas or segments of the industry, highlighting some of the issues associated with the impact of natural gas operations on the environment. 57 figs., 18 tabs

  4. Natural gas 1998: Issues and trends

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    Natural Gas 1998: Issues and Trends provides a summary of the latest data and information relating to the US natural gas industry, including prices, production, transmission, consumption, and the financial and environmental aspects of the industry. The report consists of seven chapters and five appendices. Chapter 1 presents a summary of various data trends and key issues in today`s natural gas industry and examines some of the emerging trends. Chapters 2 through 7 focus on specific areas or segments of the industry, highlighting some of the issues associated with the impact of natural gas operations on the environment. 57 figs., 18 tabs.

  5. Strategic and policy issues raised by the transition from thermal to fast nuclear systems

    International Nuclear Information System (INIS)

    2009-01-01

    The renewed interest in nuclear energy triggered by concerns about global climate change and security of supply, which could lead to substantial growth in nuclear electricity generation, enhances the attractiveness of fast neutron reactors with closed fuel cycles. Moving from the current fleet of thermal neutron reactors to fast neutron systems will require many decades and extensive RD-D efforts. This book identifies and analyses key strategic and policy issues raised by such a transition, aiming at providing guidance to decision makers on the best approaches for implementing transition scenarios. The topics covered in this book will be of interest to government and nuclear industry policy makers as well as to specialists working on nuclear energy system analyses and advanced fuel cycle issues. (author)

  6. Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal – a case study from health science [version 2; referees: 1 approved, 2 approved with reservations

    Directory of Open Access Journals (Sweden)

    Heidi Holst Madsen

    2016-09-01

    Full Text Available Unique identifiers (UID are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case with publications from the health sciences. We evaluate the matching process based on information about coverage, precision, and characteristics of publications matched versus not matched with UIDs as the match keys. We analyze this information to detect errors, if any, in the matching process. As an example we also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication.  The objective is addressed in a literature review and a case study. The literature review shows that only a few studies evaluate how well UIDs work as a match key. From the literature we identify four error types: Duplicate digital object identifiers (DOI, incorrect DOIs in reference lists and databases, DOIs not registered by the database where a bibliometric analysis is performed, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character recognition in our publication sets. In particular the duplicate DOIs constitute a problem for the calculation of bibliometric indicators as both keeping the duplicates to improve the reliability of citation counts and deleting them to improve the reliability of publication counts will distort the calculation of average number of citations per publication. The use of UIDs as a match key in citation linking is implemented in many settings, and the availability of

  7. Simple group password-based authenticated key agreements for the integrated EPR information system.

    Science.gov (United States)

    Lee, Tian-Fu; Chang, I-Pin; Wang, Ching-Cheng

    2013-04-01

    The security and privacy are important issues for electronic patient records (EPRs). The goal of EPRs is sharing the patients' medical histories such as the diagnosis records, reports and diagnosis image files among hospitals by the Internet. So the security issue for the integrated EPR information system is essential. That is, to ensure the information during transmission through by the Internet is secure and private. The group password-based authenticated key agreement (GPAKE) allows a group of users like doctors, nurses and patients to establish a common session key by using password authentication. Then the group of users can securely communicate by using this session key. Many approaches about GAPKE employ the public key infrastructure (PKI) in order to have higher security. However, it not only increases users' overheads and requires keeping an extra equipment for storing long-term secret keys, but also requires maintaining the public key system. This investigation presents a simple group password-based authenticated key agreement (SGPAKE) protocol for the integrated EPR information system. The proposed SGPAKE protocol does not require using the server or users' public keys. Each user only remembers his weak password shared with a trusted server, and then can obtain a common session key. Then all users can securely communicate by using this session key. The proposed SGPAKE protocol not only provides users with convince, but also has higher security.

  8. Identifying Memory Allocation Patterns in HEP Software

    Science.gov (United States)

    Kama, S.; Rauschmayr, N.

    2017-10-01

    HEP applications perform an excessive amount of allocations/deallocations within short time intervals which results in memory churn, poor locality and performance degradation. These issues are already known for a decade, but due to the complexity of software frameworks and billions of allocations for a single job, up until recently no efficient mechanism has been available to correlate these issues with source code lines. However, with the advent of the Big Data era, many tools and platforms are now available to do large scale memory profiling. This paper presents, a prototype program developed to track and identify each single (de-)allocation. The CERN IT Hadoop cluster is used to compute memory key metrics, like locality, variation, lifetime and density of allocations. The prototype further provides a web based visualization back-end that allows the user to explore the results generated on the Hadoop cluster. Plotting these metrics for every single allocation over time gives a new insight into application’s memory handling. For instance, it shows which algorithms cause which kind of memory allocation patterns, which function flow causes how many short-lived objects, what are the most commonly allocated sizes etc. The paper will give an insight into the prototype and will show profiling examples for the LHC reconstruction, digitization and simulation jobs.

  9. Public/private key certification authority and key distribution. Draft

    Energy Technology Data Exchange (ETDEWEB)

    Long, J.P.; Christensen, M.J.; Sturtevant, A.P.; Johnston, W.E.

    1995-09-25

    Traditional encryption, which protects messages from prying eyes, has been used for many decades. The present concepts of encryption are built from that heritage. Utilization of modern software-based encryption techniques implies much more than simply converting files to an unreadable form. Ubiquitous use of computers and advances in encryption technology coupled with the use of wide-area networking completely changed the reasons for utilizing encryption technology. The technology demands a new and extensive infrastructure to support these functions. Full understanding of these functions, their utility and value, and the need for an infrastructure, takes extensive exposure to the new paradigm. This paper addresses issues surrounding the establishment and operation of a key management system (i.e., certification authority) that is essential to the successful implementation and wide-spread use of encryption.

  10. Managing the pursuit of health and wealth: the key challenges.

    Science.gov (United States)

    Fidler, David P; Drager, Nick; Lee, Kelley

    2009-01-24

    This article forms part of a six-part Series on trade and health, and sets the stage for this Series by analysing key aspects of the relationship between trade and health. The Series takes stock of this relation and provides timely analysis of the key challenges facing efforts to achieve an appropriate balance between trade and health across a diverse range of issues. This introductory article reviews how trade and health have risen and expanded on global policy agendas in the past decade in unprecedented ways, describes how trade and health issues are respectively governed in international relations, examines the ongoing search for policy coherence between the two policy spheres, and highlights the topics of the remaining articles in the Series.

  11. Genome-wide expression profiling analysis to identify key genes in the anti-HIV mechanism of CD4+ and CD8+ T cells.

    Science.gov (United States)

    Gao, Lijie; Wang, Yunqi; Li, Yi; Dong, Ya; Yang, Aimin; Zhang, Jie; Li, Fengying; Zhang, Rongqiang

    2018-07-01

    Comprehensive bioinformatics analyses were performed to explore the key biomarkers in response to HIV infection of CD4 + and CD8 + T cells. The numbers of CD4 + and CD8 + T cells of HIV infected individuals were analyzed and the GEO database (GSE6740) was screened for differentially expressed genes (DEGs) in HIV infected CD4 + and CD8 + T cells. Gene Ontology enrichment, KEGG pathway analyses, and protein-protein interaction (PPI) network were performed to identify the key pathway and core proteins in anti-HIV virus process of CD4 + and CD8 + T cells. Finally, we analyzed the expressions of key proteins in HIV-infected T cells (GSE6740 dataset) and peripheral blood mononuclear cells(PBMCs) (GSE511 dataset). 1) CD4 + T cells counts and ratio of CD4 + /CD8 + T cells decreased while CD8 + T cells counts increased in HIV positive individuals; 2) 517 DEGs were found in HIV infected CD4 + and CD8 + T cells at acute and chronic stage with the criterial of P-value T cells. The main biological processes of the DEGs were response to virus and defense response to virus. At chronic stage, ISG15 protein, in conjunction with IFN-1 pathway might play key roles in anti-HIV responses of CD4 + T cells; and 4) The expression of ISG15 increased in both T cells and PBMCs after HIV infection. Gene expression profile of CD4 + and CD8 + T cells changed significantly in HIV infection, in which ISG15 gene may play a central role in activating the natural antiviral process of immune cells. © 2018 Wiley Periodicals, Inc.

  12. The NOAA Dataset Identifier Project

    Science.gov (United States)

    de la Beaujardiere, J.; Mccullough, H.; Casey, K. S.

    2013-12-01

    The US National Oceanic and Atmospheric Administration (NOAA) initiated a project in 2013 to assign persistent identifiers to datasets archived at NOAA and to create informational landing pages about those datasets. The goals of this project are to enable the citation of datasets used in products and results in order to help provide credit to data producers, to support traceability and reproducibility, and to enable tracking of data usage and impact. A secondary goal is to encourage the submission of datasets for long-term preservation, because only archived datasets will be eligible for a NOAA-issued identifier. A team was formed with representatives from the National Geophysical, Oceanographic, and Climatic Data Centers (NGDC, NODC, NCDC) to resolve questions including which identifier scheme to use (answer: Digital Object Identifier - DOI), whether or not to embed semantics in identifiers (no), the level of granularity at which to assign identifiers (as coarsely as reasonable), how to handle ongoing time-series data (do not break into chunks), creation mechanism for the landing page (stylesheet from formal metadata record preferred), and others. Decisions made and implementation experience gained will inform the writing of a Data Citation Procedural Directive to be issued by the Environmental Data Management Committee in 2014. Several identifiers have been issued as of July 2013, with more on the way. NOAA is now reporting the number as a metric to federal Open Government initiatives. This paper will provide further details and status of the project.

  13. Safe, Healthy and Ready to Succeed: Arizona School Readiness Key Performance Indicators

    Science.gov (United States)

    Migliore, Donna E.

    2006-01-01

    "Safe, Healthy and Ready to Succeed: Arizona School Readiness Key Performance Indicators" presents a set of baseline measurements that gauge how well a statewide system of school readiness supports is addressing issues that affect Arizona children's readiness for school. The Key Performance Indicators (KPIs) measure the system, rather…

  14. Towards Public Key Encryption Scheme Supporting Equality Test with Fine-Grained Authorization

    NARCIS (Netherlands)

    Tang, Qiang

    2011-01-01

    In this paper we investigate a new category of public key encryption schemes which supports equality test between ciphertexts. With this new primitive, two users, who possess their own public/private key pairs, can issue token(s) to a proxy to authorize it to perform equality test between their

  15. Information processing in bacteria: memory, computation, and statistical physics: a key issues review

    Science.gov (United States)

    Lan, Ganhui; Tu, Yuhai

    2016-05-01

    Living systems have to constantly sense their external environment and adjust their internal state in order to survive and reproduce. Biological systems, from as complex as the brain to a single E. coli cell, have to process these data in order to make appropriate decisions. How do biological systems sense external signals? How do they process the information? How do they respond to signals? Through years of intense study by biologists, many key molecular players and their interactions have been identified in different biological machineries that carry out these signaling functions. However, an integrated, quantitative understanding of the whole system is still lacking for most cellular signaling pathways, not to say the more complicated neural circuits. To study signaling processes in biology, the key thing to measure is the input-output relationship. The input is the signal itself, such as chemical concentration, external temperature, light (intensity and frequency), and more complex signals such as the face of a cat. The output can be protein conformational changes and covalent modifications (phosphorylation, methylation, etc), gene expression, cell growth and motility, as well as more complex output such as neuron firing patterns and behaviors of higher animals. Due to the inherent noise in biological systems, the measured input-output dependence is often noisy. These noisy data can be analysed by using powerful tools and concepts from information theory such as mutual information, channel capacity, and the maximum entropy hypothesis. This information theory approach has been successfully used to reveal the underlying correlations between key components of biological networks, to set bounds for network performance, and to understand possible network architecture in generating observed correlations. Although the information theory approach provides a general tool in analysing noisy biological data and may be used to suggest possible network architectures in

  16. Information processing in bacteria: memory, computation, and statistical physics: a key issues review.

    Science.gov (United States)

    Lan, Ganhui; Tu, Yuhai

    2016-05-01

    Living systems have to constantly sense their external environment and adjust their internal state in order to survive and reproduce. Biological systems, from as complex as the brain to a single E. coli cell, have to process these data in order to make appropriate decisions. How do biological systems sense external signals? How do they process the information? How do they respond to signals? Through years of intense study by biologists, many key molecular players and their interactions have been identified in different biological machineries that carry out these signaling functions. However, an integrated, quantitative understanding of the whole system is still lacking for most cellular signaling pathways, not to say the more complicated neural circuits. To study signaling processes in biology, the key thing to measure is the input-output relationship. The input is the signal itself, such as chemical concentration, external temperature, light (intensity and frequency), and more complex signals such as the face of a cat. The output can be protein conformational changes and covalent modifications (phosphorylation, methylation, etc), gene expression, cell growth and motility, as well as more complex output such as neuron firing patterns and behaviors of higher animals. Due to the inherent noise in biological systems, the measured input-output dependence is often noisy. These noisy data can be analysed by using powerful tools and concepts from information theory such as mutual information, channel capacity, and the maximum entropy hypothesis. This information theory approach has been successfully used to reveal the underlying correlations between key components of biological networks, to set bounds for network performance, and to understand possible network architecture in generating observed correlations. Although the information theory approach provides a general tool in analysing noisy biological data and may be used to suggest possible network architectures in

  17. Pocket radar guide key facts, equations, and data

    CERN Document Server

    Curry, G Richard

    2010-01-01

    ThePocket Radar Guideis a concise collection of key radar facts and important radar data that provides you with necessary radar information when you are away from your office or references. It includes statements and comments on radar design, operation, and performance; equations describing the characteristics and performance of radar systems and their components; and tables with data on radar characteristics and key performance issues.It is intended to supplement other radar information sources by providing a pocket companion to refresh memory and provide details whenever you need them such a

  18. Prison health service directors' views on research priorities and organizational issues in conducting research in prison: outcomes of a national deliberative roundtable.

    Science.gov (United States)

    Simpson, Paul Leslie; Guthrie, Jill; Butler, Tony

    2017-06-12

    Purpose Given that prisoners have significant health needs across most areas, the paucity of prisoner health research, and the difficulties involved in the conduct of research in this setting, there is a need to develop research priorities that align with key stakeholder groups. One such group are those responsible for health service provision in prisons - prison health service directors. The paper aims to discuss these issues. Design/methodology/approach Prison health service directors in each Australian state and territory were invited to participate in a national (deliberative) roundtable where the consensus building nominal group technique was utilized. This involved the identification of research priorities and organizational issues in conducting research with prisoners, and ranking research priorities. A thematic analysis was conducted on organizational issues. Findings In total, 13 participants attended the roundtable. Participants identified 28 research priorities and 12 organizational issues. Top ranked research priorities were mental health, cognitive and intellectual disability, post-release health maintenance, ageing prisoners, chronic health conditions and Aboriginal and Torres Strait Islander health. Themes identified from the organizational issues included prisoner access to research participation, health and research literacy of custodial staff, and institutional protectionism in response to research that may discover negative information about the custodial setting. Research limitations/implications These findings should inform future efforts to improve research infrastructures to undertake research to improve the health of people in Australian prisons, and help to align researchers' efforts with those of a key organizational stakeholder. Originality/value This is the first paper to determine the research priorities and organizational issues in conducting research in prisons of prison health service directors.

  19. Using Community-Based Participatory Research to Identify Environmental Justice Issues in an Inner-City Community and Inform Urban Planning.

    Science.gov (United States)

    Mansyur, Carol Leler; Jeng, Hueiwang Anna; Holloman, Erica; DeBrew, Linwood

    2016-01-01

    The Southeast CARE Coalition has been using community-based participatory research to examine environmental degradation in the Southeast Community, Newport News, Virginia. A survey was developed to collect assessment data. Up to 66% of respondents were concerned about environmental problems in their community. Those with health conditions were significantly more likely to identify specific environmental problems. The top 5 environmental concerns included coal dust, air quality, crime, water quality, and trash. The community-based participatory research process is building community capacity and participation, providing community input into strategic planning, and empowering community members to take control of environmental justice issues in their community.

  20. Characterizing Sleep Issues Using Twitter.

    Science.gov (United States)

    McIver, David J; Hawkins, Jared B; Chunara, Rumi; Chatterjee, Arnaub K; Bhandari, Aman; Fitzgerald, Timothy P; Jain, Sachin H; Brownstein, John S

    2015-06-08

    Sleep issues such as insomnia affect over 50 million Americans and can lead to serious health problems, including depression and obesity, and can increase risk of injury. Social media platforms such as Twitter offer exciting potential for their use in studying and identifying both diseases and social phenomenon. Our aim was to determine whether social media can be used as a method to conduct research focusing on sleep issues. Twitter posts were collected and curated to determine whether a user exhibited signs of sleep issues based on the presence of several keywords in tweets such as insomnia, "can't sleep", Ambien, and others. Users whose tweets contain any of the keywords were designated as having self-identified sleep issues (sleep group). Users who did not have self-identified sleep issues (non-sleep group) were selected from tweets that did not contain pre-defined words or phrases used as a proxy for sleep issues. User data such as number of tweets, friends, followers, and location were collected, as well as the time and date of tweets. Additionally, the sentiment of each tweet and average sentiment of each user were determined to investigate differences between non-sleep and sleep groups. It was found that sleep group users were significantly less active on Twitter (P=.04), had fewer friends (Pcost-effective, and customizable data to be gathered.

  1. Ethical issues in radiation protection

    International Nuclear Information System (INIS)

    Shrader-Frechette, K.; Persson, L.

    1997-01-01

    In this note the authors survey existing international radiation-protection recommendations of the ICRP, the IAEA, and the ILO. After outlining previous work on the ethics of radiation protection and risk assessment/management, the authors review ethical thinking on five key issues related to radiation protection and ethics. They formulate each of these five issues in terms of alternative ethical stances: (1) Equity vs. Efficiency, (2) Health vs. Economics, (3) Individual Rights vs. Societal Benefits, (4) Due Process vs. Necessary Sacrifice, and (5) Stakeholder Consent vs. Management Decisions (authors)

  2. Reproductive issues in anorexia nervosa

    Science.gov (United States)

    Hoffman, Elizabeth R; Zerwas, Stephanie C; Bulik, Cynthia M

    2011-01-01

    Despite a high prevalence of menstrual irregularities, women with anorexia nervosa are becoming pregnant. The physical and psychological demands of pregnancy and motherhood can represent an immense challenge for women already struggling with the medical and psychological stress of an eating disorder. This article summarizes key issues related to reproduction in women with anorexia nervosa, highlighting the importance of preconception counseling, adequate gestational weight gain, and sufficient pre- and post-natal nutrition. Postpartum issues including eating disorder symptom relapse, weight loss, breastfeeding, and risk of perinatal depression and anxiety are also discussed. PMID:22003362

  3. Eight Key Facets of Small Business Management.

    Science.gov (United States)

    Scott, James Calvert

    1980-01-01

    Identifies eight key facets of small business management and suggests activities that may be used to assist in their development. The key facets are (1) product or service, (2) competition, (3) marketing strategies, (4) personnel needs, (5) equipment and facility needs, (6) finances, (7) planning, and (8) entrepreneurship. (JOW)

  4. Patient-centered care: the key to cultural competence.

    Science.gov (United States)

    Epner, D E; Baile, W F

    2012-04-01

    Much of the early literature on 'cultural competence' focuses on the 'categorical' or 'multicultural' approach, in which providers learn relevant attitudes, values, beliefs, and behaviors of certain cultural groups. In essence, this involves learning key 'dos and don'ts' for each group. Literature and educational materials of this kind focus on broad ethnic, racial, religious, or national groups, such as 'African American', 'Hispanic', or 'Asian'. The problem with this categorical or 'list of traits' approach to clinical cultural competence is that culture is multidimensional and dynamic. Culture comprises multiple variables, affecting all aspects of experience. Cultural processes frequently differ within the same ethnic or social group because of differences in age cohort, gender, political association, class, religion, ethnicity, and even personality. Culture is therefore a very elusive and nebulous concept, like art. The multicultural approach to cultural competence results in stereotypical thinking rather than clinical competence. A newer, cross cultural approach to culturally competent clinical practice focuses on foundational communication skills, awareness of cross-cutting cultural and social issues, and health beliefs that are present in all cultures. We can think of these as universal human beliefs, needs, and traits. This patient centered approach relies on identifying and negotiating different styles of communication, decision-making preferences, roles of family, sexual and gender issues, and issues of mistrust, prejudice, and racism, among other factors. In the current paper, we describe 'cultural' challenges that arise in the care of four patients from disparate cultures, each of whom has advanced colon cancer that is no longer responding to chemotherapy. We then illustrate how to apply principles of patient centered care to these challenges.

  5. Painful Joints? Early Treatment for Rheumatoid Arthritis Is Key

    Science.gov (United States)

    ... Print this issue Painful Joints? Early Treatment for Rheumatoid Arthritis Is Key En español Send us your comments ... type of arthritis. It’s far more common than rheumatoid arthritis. Osteoarthritis is caused by wear and tear on ...

  6. Issues and solutions: opportunities for European LED manufacturers

    Science.gov (United States)

    Pearsall, T. P.

    2007-09-01

    Marketing studies by EPIC show significant revenue opportunities by 2012 for UHB-LEDs in the automotive, LCD backlighting, and architectural lighting sectors. The goal of this workshop on manufacturing issues is to consider five key issues for UHB-LED manufacturing and to propose solutions that will pave the way to full exploitation of the opportunities.

  7. EFFICIENT OFFICIAL STATISTICS AS A KEY TO THE ISSUE OF POST-CRISIS DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    N. I. Pashintseva

    2010-06-01

    Full Text Available Measures implemented by the Federal State Statistics Service aimed at regular monitoring of the situation in the territory of the Russian Federation have been considered in the paper. Issues related to unemployment and investment activity by enterprises in the context of the financial and economic crisis have been analyzed.

  8. Licensing the next generation of reactors in the USA: Recent experience, key issues and challenges

    International Nuclear Information System (INIS)

    Cyr, K.D.; Crockett, S.F.; Burns, S.G.

    2006-01-01

    Over the past 20 years, the US Nuclear Regulatory Commission (NRC) has spent much effort on revising its procedures for reviewing nuclear power plant designs. Earlier procedures, instituted by the NRC's predecessor, the Atomic Energy Commission, permitted the resolution of important safety and environmental issues to be delayed until construction was underway. Moreover, the principal means of public participation in the resolution was through the medium of the courtroom trial. However, under new procedures, which have been upheld in the federal courts, nearly all safety and environmental issues are resolved before construction begins, and the public participates in the resolution of these issues without having to engage in a full-blown trial. The agency believes that safety and public participation are better served by the new procedures, and that the agency is thus well-positioned to review new designs. Nonetheless, the agency continues to seek improvements in its processes. This paper was presented in an earlier form by Mr. Burns at Nuclear Inter Jura 2005. (author)

  9. A Dual Key-Based Activation Scheme for Secure LoRaWAN

    Directory of Open Access Journals (Sweden)

    Jaehyu Kim

    2017-01-01

    Full Text Available With the advent of the Internet of Things (IoT era, we are experiencing rapid technological progress. Billions of devices are connected to each other, and our homes, cities, hospitals, and schools are getting smarter and smarter. However, to realize the IoT, several challenging issues such as connecting resource-constrained devices to the Internet must be resolved. Recently introduced Low Power Wide Area Network (LPWAN technologies have been devised to resolve this issue. Among many LPWAN candidates, the Long Range (LoRa is one of the most promising technologies. The Long Range Wide Area Network (LoRaWAN is a communication protocol for LoRa that provides basic security mechanisms. However, some security loopholes exist in LoRaWAN’s key update and session key generation. In this paper, we propose a dual key-based activation scheme for LoRaWAN. It resolves the problem of key updates not being fully supported. In addition, our scheme facilitates each layer in generating its own session key directly, which ensures the independence of all layers. Real-world experimental results compared with the original scheme show that the proposed scheme is totally feasible in terms of delay and battery consumption.

  10. Developing Communities of Enquiry: Dealing with Social and Ethical Issues in Science at Key Stage 3

    Science.gov (United States)

    Dunlop, Lynda; Humes, Gill; Clarke, Linda; Martin, Valerie McKelvey

    2011-01-01

    Reproductive technologies, drug discovery and exploration of the universe are areas of contemporary research that raise issues for individuals and society. Forward Thinking, Northern Ireland uses the development of communities of enquiry to promote discussion of these and other social and ethical issues in science with students aged 11-14 years.…

  11. Energy audit practices in China: National and local experiences and issues

    International Nuclear Information System (INIS)

    Shen Bo; Price, Lynn; Lu Hongyou

    2012-01-01

    China set an ambitious goal of reducing its energy use per unit of GDP by 20% between 2006 and 2010. Much of the country’s effort is focused on improving the energy efficiency of the industrial sector, which consumes about two-thirds of China’s primary energy. Industrial energy audits are an important part of China’s efforts to improve its energy intensity. Such audits are employed to help enterprises identify energy-efficiency improvement opportunities and serve as a means to collect critical energy-consuming information. Information about energy audit practices in China is, however, little known to the outside world. This study combines a review of China’s national policies and programs on energy auditing with information collected from surveying a variety of Chinese institutions involved in energy audits. A key goal of the study is to conduct a gap analysis to identify how current practices in China related to energy auditing differ from energy auditing practices found around the world. This article presents our findings on the study of China’s energy auditing practices at the national and provincial levels. It discusses key issues related to the energy audits conducted in China and offers policy recommendations that draw upon international best practices. - Highlights: ► We examine China’s national and regional energy auditing practices in the 11th FYP. ► Energy audits have helped China achieve its energy efficiency target. ► Issues still remain preventing energy auditing from achieving its full potential. ► Gap analysis is conducted to compare with other international auditing program. ► We offer recommendations for the development of best energy audit practices.

  12. Smart-Glasses: Exposing and Elucidating the Ethical Issues.

    Science.gov (United States)

    Hofmann, Bjørn; Haustein, Dušan; Landeweerd, Laurens

    2017-06-01

    The objective of this study is to provide an overview over the ethical issues relevant to the assessment, implementation, and use of smart-glasses. The purpose of the overview is to facilitate deliberation, decision making, and the formation of knowledge and norms for this emerging technology. An axiological question-based method for human cognitive enhancement including an extensive literature search on smart-glasses is used to identify relevant ethical issues. The search is supplemented with relevant ethical issues identified in the literature on human cognitive enhancement (in general) and in the study of the technical aspects of smart-glasses. Identified papers were subject to traditional content analysis: 739 references were identified of which 247 were regarded as relevant for full text examinations, and 155 were included in the study. A wide variety of ethical issues with smart-glasses have been identified, such as issues related to privacy, safety, justice, change in human agency, accountability, responsibility, social interaction, power and ideology. Smart-glasses are envisioned to change individual human identity and behavior as well as social interaction. Taking these issues into account appears to be relevant when developing, deliberating, deciding on, implementing, and using smart-glasses.

  13. Specific work-life issues of single and childless female expatriates: An exploratory study in the Swiss context

    OpenAIRE

    Salamin Xavier

    2015-01-01

    Work life balance has been identified as a key challenge in expatriation which impacts both private and professional spheres. Especially for women work and private life issues have been found to be particularly exacerbated abroad. Up until today research on work life interface in the expatriation context has focused on expatriates relocating with a family. However single expatriates represent a non negligible proportion of the expatriate population and their work life experiences remain large...

  14. Recognition of key regions for restoration of phytoplankton communities in the Huai River basin, China

    Science.gov (United States)

    Zhao, Changsen; Liu, Changming; Xia, Jun; Zhang, Yongyong; Yu, Qiang; Eamus, Derek

    2012-02-01

    SummaryHealthy phytoplankton communities are the basis of healthy water ecosystems, and form the foundation of many freshwater food webs. Globally many freshwater ecosystems are degraded because of intensive human activities, so water ecosystem restoration is a burning issue worldwide. Selection of key regions for phytoplankton-related restoration is crucial for an effective aquatic eco-restoration. This paper presents a practical method for identification of key regions for phytoplankton-related restoration, using random forests (RFs) method to cluster sites based on dominance, biodiversity, water chemistry and ecological niche. We sampled phytoplankton for species richness and relative abundance and water quality in the Huai River basin (HRB), China to determine the phytoplankton communities' composition and structure and characterize of their ecological niches. A wider mean niche breadth of a species usually leads to a greater overlap with the niche of other species. Using these data and water quality indices, we identified the key regions for phytoplankton-related river restoration activities. Results indicate that our method for recognition of key regions is effective and practical and its application to the HRB identified the Northern Plain area as the key region for restoration. This area is severely polluted and contributes significantly to the HRB phytoplankton communities. Phytoplankton in this region is highly adaptable to environmental change and therefore will be relatively unharmed by environmental instability induced by restoration measures. During restoration, indices of water temperature, total phosphorus and chemical oxygen demand can be altered with little negative influence on phytoplankton communities, but measures that increase ammonia-nitrogen concentration would be highly detrimental. These results will provide valuable information for policy makers and stakeholders in water ecosystem restoration and sustainable basin management in the HRB.

  15. Key Past and Present Hydrologic Issues at the Waste Isolation Pilot Plant (WIPP)

    International Nuclear Information System (INIS)

    Lappin, Allen R.; McKenna, Sean A.; Davies, Peter B.

    2000-01-01

    In May 1998, the U.S; Environmental Protection Agency (EPA) certified the U.S. Department of Energy's (DOE) Waste Isolation Pilot Plant (WIPP) to be in compliance with applicable portions of regulations governing the permanent disposal of radioactive wastes. The step was accomplished after 24 years of effort by Sandia National Laboratories, extending from initial site selection, through extensive site characterization and under-ground experimentalization to evaluation and demonstration of regulatory compliance. The strong focus on regulatory compliance extended over approximately five years, culminating in DOE's submittal of a Compliance Certification Application (CCA) in October, 1996. Specific lessons learned from the WIPP'S transition from site characterization/experimental research to a successful regulatory compliance application may be of general interest to participants in other repository problems. In summary, the three examples considered in this paper indicate that: It is critical that site-characterization and performance-assessment (PA) activities in a repository project advance through multiple iterative interactions. This is because there are parallel paths of evolution-within a projecy On one hand, there is a natural development in the conceptual understanding of the site and repository geology, hydrology, and geochemistry over time, as well as a normal increase in the roles of regulatory/safety issues relative to technical issues. On the other hand there is ongoing evolution in numerical-modeling, experimental, and PA techniques, as well as in understanding of the insights gained from these activities. However, even if conceptual models do not change, the modeling and documentation techniques and detailed logic supporting these models will change; as additional relevant information is collected within or outside the project. Some issues related to general site-characterization or site-suitability will remain of interest, even after initial

  16. Psychosocial Issues in Geriatric Rehabilitation.

    Science.gov (United States)

    Rodriguez, Ricardo M

    2017-11-01

    Geriatric patients present multiple age-related challenges and needs that must be taken into account during the rehabilitation process to achieve expected goals. This article examines the importance of identifying and managing psychosocial issues commonly observed in older adults and presents strategies to optimize their rehabilitation process. Depression, anxiety, fear of falling, adjustment issues, neurocognitive disorders, and caregiver support are discussed as a selection of factors that are relevant for geriatric patients undergoing rehabilitation. An argument is made for the importance of comprehensive geriatric assessment in older adults to identify salient issues that may impact rehabilitation and quality of life. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Application of the Pareto principle to identify and address drug-therapy safety issues.

    Science.gov (United States)

    Müller, Fabian; Dormann, Harald; Pfistermeister, Barbara; Sonst, Anja; Patapovas, Andrius; Vogler, Renate; Hartmann, Nina; Plank-Kiegele, Bettina; Kirchner, Melanie; Bürkle, Thomas; Maas, Renke

    2014-06-01

    Adverse drug events (ADE) and medication errors (ME) are common causes of morbidity in patients presenting at emergency departments (ED). Recognition of ADE as being drug related and prevention of ME are key to enhancing pharmacotherapy safety in ED. We assessed the applicability of the Pareto principle (~80 % of effects result from 20 % of causes) to address locally relevant problems of drug therapy. In 752 cases consecutively admitted to the nontraumatic ED of a major regional hospital, ADE, ME, contributing drugs, preventability, and detection rates of ADE by ED staff were investigated. Symptoms, errors, and drugs were sorted by frequency in order to apply the Pareto principle. In total, 242 ADE were observed, and 148 (61.2 %) were assessed as preventable. ADE contributed to 110 inpatient hospitalizations. The ten most frequent symptoms were causally involved in 88 (80.0 %) inpatient hospitalizations. Only 45 (18.6 %) ADE were recognized as drug-related problems until discharge from the ED. A limited set of 33 drugs accounted for 184 (76.0 %) ADE; ME contributed to 57 ADE. Frequency-based listing of ADE, ME, and drugs involved allowed identification of the most relevant problems and development of easily to implement safety measures, such as wall and pocket charts. The Pareto principle provides a method for identifying the locally most relevant ADE, ME, and involved drugs. This permits subsequent development of interventions to increase patient safety in the ED admission process that best suit local needs.

  18. The building blocks of a 'Liveable Neighbourhood': Identifying the key performance indicators for walking of an operational planning policy in Perth, Western Australia.

    Science.gov (United States)

    Hooper, Paula; Knuiman, Matthew; Foster, Sarah; Giles-Corti, Billie

    2015-11-01

    Planning policy makers are requesting clearer guidance on the key design features required to build neighbourhoods that promote active living. Using a backwards stepwise elimination procedure (logistic regression with generalised estimating equations adjusting for demographic characteristics, self-selection factors, stage of construction and scale of development) this study identified specific design features (n=16) from an operational planning policy ("Liveable Neighbourhoods") that showed the strongest associations with walking behaviours (measured using the Neighbourhood Physical Activity Questionnaire). The interacting effects of design features on walking behaviours were also investigated. The urban design features identified were grouped into the "building blocks of a Liveable Neighbourhood", reflecting the scale, importance and sequencing of the design and implementation phases required to create walkable, pedestrian friendly developments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Use of a scenario-neutral approach to identify the key hydro-meteorological attributes that impact runoff from a natural catchment

    Science.gov (United States)

    Guo, Danlu; Westra, Seth; Maier, Holger R.

    2017-11-01

    Scenario-neutral approaches are being used increasingly for assessing the potential impact of climate change on water resource systems, as these approaches allow the performance of these systems to be evaluated independently of climate change projections. However, practical implementations of these approaches are still scarce, with a key limitation being the difficulty of generating a range of plausible future time series of hydro-meteorological data. In this study we apply a recently developed inverse stochastic generation approach to support the scenario-neutral analysis, and thus identify the key hydro-meteorological variables to which the system is most sensitive. The stochastic generator simulates synthetic hydro-meteorological time series that represent plausible future changes in (1) the average, extremes and seasonal patterns of rainfall; and (2) the average values of temperature (Ta), relative humidity (RH) and wind speed (uz) as variables that drive PET. These hydro-meteorological time series are then fed through a conceptual rainfall-runoff model to simulate the potential changes in runoff as a function of changes in the hydro-meteorological variables, and runoff sensitivity is assessed with both correlation and Sobol' sensitivity analyses. The method was applied to a case study catchment in South Australia, and the results showed that the most important hydro-meteorological attributes for runoff were winter rainfall followed by the annual average rainfall, while the PET-related meteorological variables had comparatively little impact. The high importance of winter rainfall can be related to the winter-dominated nature of both the rainfall and runoff regimes in this catchment. The approach illustrated in this study can greatly enhance our understanding of the key hydro-meteorological attributes and processes that are likely to drive catchment runoff under a changing climate, thus enabling the design of tailored climate impact assessments to specific

  20. Issues engulfed Saudi Arabia construction workers

    Science.gov (United States)

    Al-Emad, N. H.; Rahman, I. A.

    2018-04-01

    This paper presents an exploratory study conducted in Makkah city to uncover issues faced by construction workers from the construction leaders’ perspective. Eleven construction leaders/experts were interviewed to unleash their experiences on handling the foreign workers working in Makkah construction projects. Most of the experts are senior management staffs with more than 10 years’ working experience in Saudi Arabia construction industry. The interviews were carried out in semi structured mode where all the information was captured manually and also electronically. The identified issues were sorted based on its commonality into 10 clusters. Hence in each cluster, the numbers of issue considered by the experts are reflecting the importance of that particular cluster. The result of the clusters according to the number of issues mentioned by the experts are safety issues, restricted government regulation, demotivated issues, lack of quality workers, poor living quality, communication barriers, adaption issues, poor attitudes, lack of logistical arrangements and lack of education. With these identified issues it will assist the construction players in the construction industry of Saudi Arabia in dealing with their workers.

  1. Hillslope characterization: Identifying key controls on local-scale plant communities' distribution using remote sensing and subsurface data fusion.

    Science.gov (United States)

    Falco, N.; Wainwright, H. M.; Dafflon, B.; Leger, E.; Peterson, J.; Steltzer, H.; Wilmer, C.; Williams, K. H.; Hubbard, S. S.

    2017-12-01

    Mountainous watershed systems are characterized by extreme heterogeneity in hydrological and pedological properties that influence biotic activities, plant communities and their dynamics. To gain predictive understanding of how ecosystem and watershed system evolve under climate change, it is critical to capture such heterogeneity and to quantify the effect of key environmental variables such as topography, and soil properties. In this study, we exploit advanced geophysical and remote sensing techniques - coupled with machine learning - to better characterize and quantify the interactions between plant communities' distribution and subsurface properties. First, we have developed a remote sensing data fusion framework based on the random forest (RF) classification algorithm to estimate the spatial distribution of plant communities. The framework allows the integration of both plant spectral and structural information, which are derived from multispectral satellite images and airborne LiDAR data. We then use the RF method to evaluate the estimated plant community map, exploiting the subsurface properties (such as bedrock depth, soil moisture and other properties) and geomorphological parameters (such as slope, curvature) as predictors. Datasets include high-resolution geophysical data (electrical resistivity tomography) and LiDAR digital elevation maps. We demonstrate our approach on a mountain hillslope and meadow within the East River watershed in Colorado, which is considered to be a representative headwater catchment in the Upper Colorado Basin. The obtained results show the existence of co-evolution between above and below-ground processes; in particular, dominant shrub communities in wet and flat areas. We show that successful integration of remote sensing data with geophysical measurements allows identifying and quantifying the key environmental controls on plant communities' distribution, and provides insights into their potential changes in the future

  2. Examining Key Issues Underlying the Audit Commission Reports on SEN Policy Paper 1 (5th Series)

    Science.gov (United States)

    Norwich, Brahm; Beek, Chris; Richardson, Penny; Gray, Peter

    2004-01-01

    This book is the first publication in the fifth series of seminars organised by the SEN Policy Options Steering Group to examine policy issues to do with special educational needs. The aim of the seminar was to examine in depth several underlying issues raised by the recent Audit Commission Reports on special educational needs. The seminar…

  3. Teaching Public Administration: Key Themes 1996-2016

    Science.gov (United States)

    Fenwick, John

    2018-01-01

    In this article, the aim is to explore some of the key themes to emerge in the journal during the past two decades. Each selected theme will be reviewed in the light of issues raised in particular papers. The aim of this approach is, first, to facilitate reflection upon the contribution of the journal as its subject matter has moved from a concern…

  4. Medical technology as a key driver of rising health expenditure: disentangling the relationship

    Science.gov (United States)

    Sorenson, Corinna; Drummond, Michael; Bhuiyan Khan, Beena

    2013-01-01

    Health care spending has risen steadily in most countries, becoming a concern for decision-makers worldwide. Commentators often point to new medical technology as the key driver for burgeoning expenditures. This paper critically appraises this conjecture, based on an analysis of the existing literature, with the aim of offering a more detailed and considered analysis of this relationship. Several databases were searched to identify relevant literature. Various categories of studies (eg, multivariate and cost-effectiveness analyses) were included to cover different perspectives, methodological approaches, and issues regarding the link between medical technology and costs. Selected articles were reviewed and relevant information was extracted into a standardized template and analyzed for key cross-cutting themes, ie, impact of technology on costs, factors influencing this relationship, and methodological challenges in measuring such linkages. A total of 86 studies were reviewed. The analysis suggests that the relationship between medical technology and spending is complex and often conflicting. Findings were frequently contingent on varying factors, such as the availability of other interventions, patient population, and the methodological approach employed. Moreover, the impact of technology on costs differed across technologies, in that some (eg, cancer drugs, invasive medical devices) had significant financial implications, while others were cost-neutral or cost-saving. In light of these issues, we argue that decision-makers and other commentators should extend their focus beyond costs solely to include consideration of whether medical technology results in better value in health care and broader socioeconomic benefits. PMID:23807855

  5. On the Security of a Simple Three-Party Key Exchange Protocol without Server’s Public Keys

    Directory of Open Access Journals (Sweden)

    Junghyun Nam

    2014-01-01

    Full Text Available Authenticated key exchange protocols are of fundamental importance in securing communications and are now extensively deployed for use in various real-world network applications. In this work, we reveal major previously unpublished security vulnerabilities in the password-based authenticated three-party key exchange protocol according to Lee and Hwang (2010: (1 the Lee-Hwang protocol is susceptible to a man-in-the-middle attack and thus fails to achieve implicit key authentication; (2 the protocol cannot protect clients’ passwords against an offline dictionary attack; and (3 the indistinguishability-based security of the protocol can be easily broken even in the presence of a passive adversary. We also propose an improved password-based authenticated three-party key exchange protocol that addresses the security vulnerabilities identified in the Lee-Hwang protocol.

  6. Teaching nuclear issues

    International Nuclear Information System (INIS)

    Hicks, D.W.

    1986-01-01

    This paper is based on the assumption that the nuclear debate, both globally and within Britain, is one of critical importance in the late twentieth century and that it should therefore, at some juncture, be explored as part of the school curriculum. An essential part of 'good education' in a democratic society is to teach young people how to think about such an issue, but not what to think about it. This paper attempts to set out some of the key issues and dilemmas in relation to what we may call 'nuclear education'. It perhaps asks more questions than it gives answers, but they are all essential questions which teachers must ask themselves if they are to teach sensitively about these matters. Some of these questions are given as examples. (author)

  7. An Overview of Key Indicators and Evaluation Tools for Assessing Housing Quality: A Literature Review

    Science.gov (United States)

    Sinha, Rajan Chandra; Sarkar, Satyaki; Mandal, Nikhil Ranjan

    2017-09-01

    The issue of the housing quality has been addressed for various stakeholders at different levels. There exist varied opinion about its measurability and possible applications. Thus the study is carried out to have an insight into the concept of housing quality and its relevance in the changing demographics, technological, socio-economic and socio-cultural conditions. This study attempts to summarize the literature that addresses past research concerned with factors related to housing quality, its measurement methodology and critically examines the broad key indicators identified to have impact upon enhancing the housing quality. This work discusses the recent techniques which are extensively used for analysis of housing quality.

  8. Degradation of aged plants by corrosion: 'Long cell action' in unresolved corrosion issues

    International Nuclear Information System (INIS)

    Saji, Genn

    2009-01-01

    In a series of previously published papers the author has identified that 'long cell action' corrosion plays a pivotal role in practically all unresolved corrosion issues for all types of nuclear power plants (e.g. PWR/VVER, BWR/RBMK and CANDU). Some of these unresolved issues are IGSCC, PWSCC, AOA and FAC (erosion-corrosion). In conventional corrosion science it is well established that 'long cell action' can seriously accelerate or suppress the local cell corrosion activities. Although long cell action is another fundamental mechanism of corrosion, especially in a 'soil corrosion' arena, potential involvement of this corrosion process has never been studied in nuclear and fossil power plants as far as the author has been able to establish. The author believes that the omission of this basic corrosion mechanism is the root cause of practically all un-resolved corrosion issues. In this paper, the author further elaborated on his assessment to other key corrosion issues, e.g. steam generator and turbine corrosion issues, while briefly summarizing previous discussions for completeness purposes, as well as introducing additional experimental and theoretical evidence of this basic corrosion mechanism. Due to the importance of this potential mechanism the author is calling for institutional review activities and further verification experiments in the form of a joint international project.

  9. Ethical issues in medical research in the developing world: a report on a meeting organised by Fondation Mérieux.

    Science.gov (United States)

    Perrey, Christophe; Wassenaar, Douglas; Gilchrist, Shawn; Ivanoff, Bernard

    2009-08-01

    This paper reports on a multidisciplinary meeting held to discuss ethical issues in medical research in the developing world. Many studies, including clinical trials, are conducted in developing countries with a high burden of disease. Conditions under which this research is conducted vary because of differences in culture, public health, political, legal and social contexts specific to these countries. Research practices, including standards of care for participants, may vary as a result. It is therefore not surprising that ethical issues emerge. This meeting sought to identify and discuss these issues from the perspectives of the many actors in such research, including community representatives, with a view to finding ethical and pragmatic solutions to these issues. Dialogue between these actors was also promoted, with a view to identifying the need to develop such dialogue in future. Drawing from the experiences of the speakers, the colloquium attempted to outline some answers to several key questions characterising the field today. Experiences related to epidemiologic research, vaccine trials, drug trials, diagnostic tests and to some fundamental ethical issues in health research. Speakers were from different countries, disciplines and professions. The meeting provided a forum for consultation and debate between different ethics actors. Both encouraging findings and challenges emerged.

  10. Integrating Gender Issues in Recovery and Reconstruction Planning

    OpenAIRE

    World Bank

    2011-01-01

    This note on integrating gender issues in recovery and reconstruction planning is the fifth in a series of guidance notes on gender issues in Disaster Risk Management (DRM) in East Asia and Pacific region. There are number of key challenges that women face in different elements of post disaster risk reconstruction and recovery. This note addresses the following bottlenecks: a) housing, lan...

  11. ITER - torus vacuum pumping system remote handling issues

    International Nuclear Information System (INIS)

    Stringer, J.

    1992-11-01

    This report describes further design issues concerning remote maintenance of torus vacuum pumping systems options for ITER. The key issues under investigation in this report are flask support systems for valve seal exchange operations for the compound cryopump scheme and remote maintenance of a proposed multiple turbomolecular pump (TMP) system, an alternative ITER torus exhaust pumping option. Previous studies have shown that the overhead support methods for seal exchange flask equipment could malfunction due to valve/flask misalignment. A floor-mounted support system is described in this report. This scheme provides a more rigid support system for seal exchange operations. An alternative torus pumping system, based on the use of multiple TMPs, is studied from a remote maintenance standpoint. In this concept, centre distance spacing for pump/valve assemblies is too restrictive for remote maintenance. Recommendations are made for adequate spacing of these assemblies based on commercially-available 0.8 m and 1.0 m diameter valves. Fewer pumps will fit in this arrangement, which implies a need for larger TMPs. Pumps of this size are not commercially available. Other concerns regarding the servicing and storage of remote handling equipment in cells are also identified. (9 figs.)

  12. Authenticated multi-user quantum key distribution with single particles

    Science.gov (United States)

    Lin, Song; Wang, Hui; Guo, Gong-De; Ye, Guo-Hua; Du, Hong-Zhen; Liu, Xiao-Fen

    2016-03-01

    Quantum key distribution (QKD) has been growing rapidly in recent years and becomes one of the hottest issues in quantum information science. During the implementation of QKD on a network, identity authentication has been one main problem. In this paper, an efficient authenticated multi-user quantum key distribution (MQKD) protocol with single particles is proposed. In this protocol, any two users on a quantum network can perform mutual authentication and share a secure session key with the assistance of a semi-honest center. Meanwhile, the particles, which are used as quantum information carriers, are not required to be stored, therefore the proposed protocol is feasible with current technology. Finally, security analysis shows that this protocol is secure in theory.

  13. Research Issues in Information Access.

    Science.gov (United States)

    Molholt, Pat

    1989-01-01

    Discusses traditional library approaches to access to information and the possible impact of information technologies, library automation, and artificial intelligence. Access issues raised by these technologies are identified and a research agenda to explore these issues is outlined. (31 references) (CLB)

  14. Global Nursing Issues and Development: Analysis of World Health Organization Documents.

    Science.gov (United States)

    Wong, Frances Kam Yuet; Liu, Huaping; Wang, Hui; Anderson, Debra; Seib, Charrlotte; Molasiotis, Alex

    2015-11-01

    To analyze World Health Organization (WHO) documents to identify global nursing issues and development. Qualitative content analysis. Documents published by the six WHO regions between 2007 and 2012 and with key words related to nurse/midwife or nursing/midwifery were included. Themes, categories, and subcategories were derived. The final coding reached 80% agreement among three independent coders, and the final coding for the discrepant coding was reached by consensus. Thirty-two documents from the regions of Europe (n = 19), the Americas (n = 6), the Western Pacific (n = 4), Africa (n = 1), the Eastern Mediterranean (n = 1), and Southeast Asia (n = 1) were examined. A total of 385 units of analysis dispersed in 31 subcategories under four themes were derived. The four themes derived (number of unit of analysis, %) were Management & Leadership (206, 53.5), Practice (75, 19.5), Education (70, 18.2), and Research (34, 8.8). The key nursing issues of concern at the global level are workforce, the impacts of nursing in health care, professional status, and education of nurses. International alliances can help advance nursing, but the visibility of nursing in the WHO needs to be strengthened. Organizational leadership is important in order to optimize the use of nursing competence in practice and inform policy makers regarding the value of nursing to promote people's health. © 2015 Sigma Theta Tau International.

  15. Economic issues relating to power sector

    International Nuclear Information System (INIS)

    Nair, S.K.N.; Mohan, Rakesh

    1998-01-01

    Financial distress alongside high rates of growth, stagnant organizations coexistent with upgraded technologies, richly endowed regions marked by low levels of electricity consumption and the long wait for private power in face of mounting shortfalls are among the contradictions marking the power sector. Decades of public financing support could shore up the rates of growth but forms of past intervention failed to address critical institutional and regulatory issues. Key areas that need intervention have now been identified, although several are yet to be tackled. This paper discusses the more important of the problem areas holding up significant economic gains that could be realized through cost reductions, the needed levels of investments, operation of market forces and targeting of resources to promote equitable growth. The slow pace of progress is a matter for concern. Effectiveness of many of the policy initiatives of government is also dependent on providing well thought out policy supports. (author)

  16. Economics of Food Security: Selected Issues

    Directory of Open Access Journals (Sweden)

    Silvia L. Saravia-Matus

    2012-05-01

    Full Text Available The present article reviews selected key challenges regarding food security from both an academic and policy-oriented angle. In the analysis of the main constraints to achieve food access and availability in low and high-income societies, a detailed distinction is made between technological and institutional aspects. In the case of low-income economies, the emphasis is placed on the socio-economic situation and performance of small-scale farmers while in high-income economies the focus is shifted towards issues of price volatility, market stability and food waste. In both scenarios, productivity and efficiency in the use of resources are also considered. The objective of this assessment is to identify the type of policy support which would be most suitable to fulfil the increasing food demand. Innovation programmes and policies which inte- grate institutional coordination and technical support are put forward as strategic tools in the achievement of food security goals at regional and global level.

  17. Key elements on implementing an occupational health and safety management system using ISO 45001 standard

    Directory of Open Access Journals (Sweden)

    Darabont Doru Costin

    2017-01-01

    Full Text Available Occupational health and safety (OHS management system is one of the main elements of the company’s general management system. During last decade, Romanian companies gained a valuable experience on implementing this type of management systems, using OHSAS 18001 referential and standard. However, the projected release of the ISO 45001 represents a new approach which requires the companies to take in consideration new key elements for a successful implementation of the OHS management system. The aim of the paper is to identify and analyse these key elements, by integration of the following issues: standard requirements, Romanian OHS legislation and good practice examples, including the general control measures for new and emerging risks such as psycho-social risks, workforce ageing and new technologies. The study results represent an important work instrument for each company interested to implement or upgrade its OHS management system using ISO 45001 standard and could be used regardless the company size or activity domain.

  18. Space reactor fuels performance and development issues

    International Nuclear Information System (INIS)

    Wewerka, E.M.

    1984-01-01

    Three compact reactor concepts are now under consideration by the US Space Nuclear Power Program (the SP-100 Program) as candidates for the first 100-kWe-class space reactor. Each of these reactor designs puts unique constraints and requirements on the fuels system, and raises issues of fuel systems feasibility and performance. This paper presents a brief overview of the fuel requirements for the proposed space reactor designs, a delineation of the technical feasibility issues that each raises, and a description of the fuel systems development and testing program that has been established to address key technical issues

  19. Identifying Clusters of Complex Urban–Rural Issues as Part of Policy Making Process Using a Network Analysis Approach: A Case Study in Bahía de Los Ángeles, Mexico

    Directory of Open Access Journals (Sweden)

    Javier Sandoval

    2017-06-01

    Full Text Available Improving human settlements diagnosis is a key factor in effective urban planning and the design of efficient policy making. In this paper, we illustrate how network theory concepts can be applied to reveal the topological structure of functional relationships in a network of heterogeneous urban–rural issues. This mapping is done using clustering algorithms and centrality value techniques. By analyzing emergent groups of urban–rural related issues, our methodology was applied to a rural community, considering in this exercise environmental matters and real estate interests as a way to better understand the structure of salient issues in the context of its urban development program design. Results show clusters that arrange themselves not by an obvious similarity in their constituent components, but by relations observed in urban–rural settings that hint on the issues that the urban development program must focus. Due to its complex nature, the classification of these emerging clusters and how they must be treated in traditional planning instruments is a new challenge that this novel methodology reveals.

  20. Identifying key conservation threats to Alpine birds through expert knowledge

    Science.gov (United States)

    Pedrini, Paolo; Brambilla, Mattia; Rolando, Antonio; Girardello, Marco

    2016-01-01

    Alpine biodiversity is subject to a range of increasing threats, but the scarcity of data for many taxa means that it is difficult to assess the level and likely future impact of a given threat. Expert opinion can be a useful tool to address knowledge gaps in the absence of adequate data. Experts with experience in Alpine ecology were approached to rank threat levels for 69 Alpine bird species over the next 50 years for the whole European Alps in relation to ten categories: land abandonment, climate change, renewable energy, fire, forestry practices, grazing practices, hunting, leisure, mining and urbanization. There was a high degree of concordance in ranking of perceived threats among experts for most threat categories. The major overall perceived threats to Alpine birds identified through expert knowledge were land abandonment, urbanization, leisure and forestry, although other perceived threats were ranked highly for particular species groups (renewable energy and hunting for raptors, hunting for gamebirds). For groups of species defined according to their breeding habitat, open habitat species and treeline species were perceived as the most threatened. A spatial risk assessment tool based on summed scores for the whole community showed threat levels were highest for bird communities of the northern and western Alps. Development of the approaches given in this paper, including addressing biases in the selection of experts and adopting a more detailed ranking procedure, could prove useful in the future in identifying future threats, and in carrying out risk assessments based on levels of threat to the whole bird community. PMID:26966659

  1. Identifying key conservation threats to Alpine birds through expert knowledge

    Directory of Open Access Journals (Sweden)

    Dan E. Chamberlain

    2016-02-01

    Full Text Available Alpine biodiversity is subject to a range of increasing threats, but the scarcity of data for many taxa means that it is difficult to assess the level and likely future impact of a given threat. Expert opinion can be a useful tool to address knowledge gaps in the absence of adequate data. Experts with experience in Alpine ecology were approached to rank threat levels for 69 Alpine bird species over the next 50 years for the whole European Alps in relation to ten categories: land abandonment, climate change, renewable energy, fire, forestry practices, grazing practices, hunting, leisure, mining and urbanization. There was a high degree of concordance in ranking of perceived threats among experts for most threat categories. The major overall perceived threats to Alpine birds identified through expert knowledge were land abandonment, urbanization, leisure and forestry, although other perceived threats were ranked highly for particular species groups (renewable energy and hunting for raptors, hunting for gamebirds. For groups of species defined according to their breeding habitat, open habitat species and treeline species were perceived as the most threatened. A spatial risk assessment tool based on summed scores for the whole community showed threat levels were highest for bird communities of the northern and western Alps. Development of the approaches given in this paper, including addressing biases in the selection of experts and adopting a more detailed ranking procedure, could prove useful in the future in identifying future threats, and in carrying out risk assessments based on levels of threat to the whole bird community.

  2. Identifying Topics in Microblogs Using Wikipedia.

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  3. Special issue review of pollution prevention management within the Department of Energy, final report

    International Nuclear Information System (INIS)

    1994-08-01

    The Department of Energy's (DOE) national role and overall mission has been undergoing significant change. In the post-Cold War era, a new emphasis on cleaning up the wastes from the past has emerged. These changes provide both significant challenges as well as new opportunities for DOE. While the challenges may seem overwhelming as DOE realizes the magnitude of its environmental problems, its network of national laboratories and sites provide the resources to become a leader in environmental management through the development of new technologies and management practices. Because of the growing importance of pollution prevention in the United States and more specifically to DOE's environmental management strategy, the Office of Environmental Audit (EH-24) identified this as an area worthy of a Special Issue Review. A Special Issue Review is not an audit but rather an in-depth review of key environmental programs or activities which cut across organizational boundaries. The purpose of a Special Issue Review is to identify strengths and weaknesses of a program as well as significant crosscutting issues or challenges that are important to the future success of that program. The scope of the review included an assessment of pollution prevention program activities at Headquarters, selected operations offices, and selected sites offices and contractor organizations. All aspects of a pollution prevention program were considered including program strategy, infrastructure, management systems, and implementation practices. Also summarized are future pollution prevention challenges and recommendations

  4. Critical Issues and Key Points from the Survey to the Creation of the Historical Building Information Model: the Case of Santo Stefano Basilica

    Science.gov (United States)

    Castagnetti, C.; Dubbini, M.; Ricci, P. C.; Rivola, R.; Giannini, M.; Capra, A.

    2017-05-01

    The new era of designing in architecture and civil engineering applications lies in the Building Information Modeling (BIM) approach, based on a 3D geometric model including a 3D database. This is easier for new constructions whereas, when dealing with existing buildings, the creation of the BIM is based on the accurate knowledge of the as-built construction. Such a condition is allowed by a 3D survey, often carried out with laser scanning technology or modern photogrammetry, which are able to guarantee an adequate points cloud in terms of resolution and completeness by balancing both time consuming and costs with respect to the request of final accuracy. The BIM approach for existing buildings and even more for historical buildings is not yet a well known and deeply discussed process. There are still several choices to be addressed in the process from the survey to the model and critical issues to be discussed in the modeling step, particularly when dealing with unconventional elements such as deformed geometries or historical elements. The paper describes a comprehensive workflow that goes through the survey and the modeling, allowing to focus on critical issues and key points to obtain a reliable BIM of an existing monument. The case study employed to illustrate the workflow is the Basilica of St. Stefano in Bologna (Italy), a large monumental complex with great religious, historical and architectural assets.

  5. Progress on resolution of major surety issues

    International Nuclear Information System (INIS)

    Bell, C.R.; Boudreau, J.M.

    1985-01-01

    This paper presents a summary of the major surety issues (safety, environmental protection, sageguards, reliability, quality assurance) that have been identified during Phase I of the SP-100 Program and the progress that has been made in analyzing the most important of these issues in the context of the conceptual design effort. These issues have been identified as inadvertent criticality, toxic material release and dispersion, radiation exposure following end-of-life reentry, potential diversion of special nuclear material, failure to achieve end-of-life neutronic shutdown, and structural predictability for end-of-life re-entry or boost. Because of the complexity of these issues, a simplified conservative approach was taken during Phase I. Progress on these issues has been mainly in the area of increased understanding of the issues, identification of design features to resolve the issues, and quantitative evaluations of the surety characteristics of the various design concepts

  6. Postnatal Depression Is a Public Health Nursing Issue: Perspectives from Norway and Ireland

    Directory of Open Access Journals (Sweden)

    Kari Glavin

    2013-01-01

    Full Text Available The framework provided by the Millennium Development Goals includes maternal health as an area of priority. Postnatal depression (PND is a serious public health issue because it occurs at a crucial time in a mothers’ life, can persist for long periods, and can have adverse effects on partners and the emotional, behavioural, and cognitive development of infants and children. Internationally, public health nurses (PHNs are key professionals in the delivery of health care to mothers in the postpartum period, and international research collaborations are encouraged. Two researchers from the European Academy of Nursing Science (EANS identified a need to collaborate and strengthen research capacity and discussion on postnatal depression, a public health nursing issue in both countries. Within the context of public health and public health nursing in Ireland and Norway, the aim of this paper is to present a discussion on the concept of PND, prevalence, and outcomes; screening issues for PHNs; and the research evidence of the benefits of social support in facilitating recovery for new mothers.

  7. Between Land and People: A Review of Socioeconomic Issues within the context of Rapid Development in Iskandar Malaysia

    Directory of Open Access Journals (Sweden)

    Zahid Sultan

    2016-09-01

    Full Text Available In response to globalization and economic competitiveness, Malaysia launched six economic development corridors, covering all the potential areas in Malaysia, and Johor Bahru is one of them. Iskandar Malaysia was launched in 2006 for future economic development in the country as well as to cater the needs of Johor Bahru to modernize its urban and economic infrastructure. Situated in a strategic location and space, Iskandar Malaysia is targeted to be the player of catalytic investment role that will bring direct and indirect investment to Johor. The whole landscape of Johor Bahru is now transforming dramatically, thus worrying the locals and the environmentalists. Environmental issues as well as the concern for social inequality issues have been raised by the locals. Hence, the aim of this study is to address the issues created by the rapid development of Iskandar Malaysia, particularly in Johor Bahru and Nusajaya. The objectives of this paper are to assess the consequences of the coastal land reclamation for Danga Bay waterfront city development and to identify the impact of new-build gentrification towards the local people. The research identifies key social and economic issues and the impacts of these issues have also been identified. To achieve the objective of the study a detailed review on secondary data has been done. The study found that more cooperation and attention from the local authorities, stakeholders and public is needed to ensure urban regeneration and to achieve the objective of social inclusiveness as promised by the vision of Iskandar Malaysia.

  8. Key Geomechanics Issues at the Waste Isolation Pilot Plant Geomechanics

    International Nuclear Information System (INIS)

    HANSEN, FRANCIS D.

    1999-01-01

    Mechanical and hydrological properties of rock salt provide excellent bases for geological isolation of hazardous materials. Regulatory compliance determinations for the Waste Isolation Pilot Plant (WIPP) stand as testament to the widely held conclusion that salt provides excellent isolation properties. The WIPP saga began in the 1950s when the U.S. National Academy of Sciences (NAS) recommended a salt vault as a promising solution to the national problem of nuclear waste disposal. For over 20 years, the Scientific basis for the NAS recommendation has been fortified by Sandia National Laboratories through a series of large scale field tests and laboratory investigations of salt properties. These scientific investigations helped develop a comprehensive understanding of salt's 4 reformational behavior over an applicable range of stresses and temperatures. Sophisticated constitutive modeling, validated through underground testing, provides the computational ability to model long-term behavior of repository configurations. In concert with advancement of the mechanical models, fluid flow measurements showed not only that the evaporite lithology was essentially impermeable but that the WIPP setting was hydrologically inactive. Favorable mechanical properties ensure isolation of materials placed in a salt geological setting. Key areas of the geomechanics investigations leading to the certification of WIPP are in situ experiments, laboratory tests, and shaft seal design

  9. Effectiveness of Mentoring Program Practices. Research in Action. Issue 2

    Science.gov (United States)

    DuBois, David L.

    2007-01-01

    This article focuses on mentoring program practices in relation to issues of effectiveness, while recognizing that implications for program quality conceptualized more broadly is a key concern in need of greater investigation. The author provides an overview of selected conceptual and methodological issues involved with identification of…

  10. Setting Organizational Key Performance Indicators in the Precision Machine Industry

    Directory of Open Access Journals (Sweden)

    Mei-Hsiu Hong

    2015-11-01

    Full Text Available The aim of this research is to define (or set organizational key performance indicators (KPIs in the precision machine industry using the concept of core competence and the supply chain operations reference (SCOR model. The research is conducted in three steps. In the first step, a benchmarking study is conducted to collect major items of core competence and to group them into main categories in order to form a foundation for the research. In the second step, a case company questionnaire and interviews are conducted to identify the key factors of core competence in the precision machine industry. The analysis is conducted based on four dimensions and hence several analysis rounds are completed. Questionnaire data is analyzed with grey relational analysis (GRA and resulted in 5–6 key factors in each dimension or sub-dimension. Based on the conducted interviews, 13 of these identified key factors are separated into one organization objective, five key factors of core competence and seven key factors of core ability. In the final step, organizational KPIs are defined (or set for the five identified key factors of core competence. The most competitive core abilities for each of the five key factors are established. After that, organizational KPIs are set based on the core abilities within 3 main categories of KPIs (departmental, office grade and hierarchal for each key factor. The developed KPI system based on organizational objectives, core competences, and core abilities allow enterprises to handle dynamic market demand and business environments, as well as changes in overall corporate objectives.

  11. Identifying palliative care issues in inpatients dying following stroke.

    Science.gov (United States)

    Ntlholang, O; Walsh, S; Bradley, D; Harbison, J

    2016-08-01

    Stroke leads to high mortality and morbidity but often there is a conflict between need for palliative care and avoidance of 'therapeutic nihilism'. We aimed to elicit the palliative care needs of stroke patients at the end of their lives in our unit with a low overall mortality rate (1 month: 8.8 %, inpatient: 12.9 %). We identified consecutive stroke patients who died over 2 years. Their clinical records were used for data collection. Of 54 deaths, 33 (61.1 %) were females, mean (SD) age at death was 79.3 ± 12.9 years. 41 (75.9 %) died after first stroke, 9 (16.7 %) were inpatient strokes, 7 (13.0 %) thrombolysed and 7 (13.0 %) had strokes as treatment complication. There were clear statements recorded in 26 (48.1 %) that patients were dying and death was thought to be due primarily to extent of brain injury in 24 (44.4 %). Palliative needs identified included dyspnoea 21 (38.9 %), pain 17 (31.5 %), respiratory secretions 17 (31.5 %), agitation 14 (25.9 %) and psychological distress 1 (1.9 %). Symptoms were due to premorbid diseases in 6 (11.1 %). Palliative care expertise were sought in 13 (24.1 %) and continuous subcutaneous infusion was used in 18 (33.3 %) to control symptoms. 4 (7.4 %) subjects underwent cardiac arrest calls and 9 (16.7 %) deaths occurred in ICU/HDU. The median Stroke-Death interval was 20 days (range 0-389). Do Not Attempt Resuscitation (DNAR) orders were in place in 86.8 % of patients. The median DNAR-Death interval was 7 days (range 0-311) with 7-day DNAR-Death rate of 53.2 % and 30-day of 78.7 % of the total deaths. Dyspnoea, pain and respiratory secretions were identified as the main palliative care needs.

  12. Electronic Publishing: Introduction to This Issue.

    Science.gov (United States)

    Siegel, Martin A.

    1994-01-01

    Provides an overview of this special issue that addresses the possibilities and implications of electronic publishing and information dissemination as key components of effective education. Highlights include the theory and framework of electronic publishing; differences between electronic text and print; development of new educational materials;…

  13. Identifying Key Flavors in Strawberries Driving Liking via Internal and External Preference Mapping.

    Science.gov (United States)

    Oliver, Penelope; Cicerale, Sara; Pang, Edwin; Keast, Russell

    2018-04-01

    Australian consumers desire the development of a more flavorsome Australian strawberry cultivar. To aid in the development of well-liked strawberries, the attributes driving liking need to be identified. The objective of this research is to apply Preference Mapping (PM) techniques to the descriptive profile of commercial and newly bred strawberry cultivars, together with consumer preference data to determine the flavors contributing to liking. A trained sensory panel (n = 12) used Quantitative Descriptive Analysis (QDA®) methodology to evaluate two appearance, seven aroma, five texture, 10 flavor and 10 aftertaste attributes of three commercial strawberry cultivars and six elite breeding lines grown in Victoria, Australia. Strawberry consumers (n = 150) assessed their liking of the same strawberry cultivars. QDA® significantly discriminated strawberries on 28 of the 34 sensory attributes. There were significant differences in hedonic ratings of strawberries (F(8,714) = 11.5, P = 0.0001), with Hierarchical Cluster Analysis (HCA) identifying three consumer clusters each displaying differing patterns of preference. Internal and external PM techniques were applied to the data to identify the attributes driving consumer acceptability. Sweet, berry, caramel, fruity and floral attributes were identified as most contributing to liking. Sour, citrus, green, astringent, firm and gritty attributes were conversely associated with a reduction in consumer liking. Elite Lines 2 and 6 have been identified as having the broadest appeal, satisfying between 60% and 70% of consumers in the population assessed, thus the introduction of these cultivars should satisfy the largest group of consumers in the Australian market. The results of this research could be applied to breeding programs, to ensure newly bred cultivars express characteristics that were identified as well-liked amongst consumers. In addition, this research provides evidence for marketing strawberries by

  14. Identifying the barriers to conducting outcomes research in integrative health care clinic settings - a qualitative study

    Directory of Open Access Journals (Sweden)

    Findlay-Reece Barbara

    2010-01-01

    Full Text Available Abstract Background Integrative health care (IHC is an interdisciplinary blending of conventional medicine and complementary and alternative medicine (CAM with the purpose of enhancing patients' health. In 2006, we designed a study to assess outcomes that are relevant to people using such care. However, we faced major challenges in conducting this study and hypothesized that this might be due to the lack of a research climate in these clinics. To investigate these challenges, we initiated a further study in 2008, to explore the reasons why IHC clinics are not conducting outcomes research and to identify strategies for conducting successful in-house outcomes research programs. The results of the latter study are reported here. Methods A total of 25 qualitative interviews were conducted with key participants from 19 IHC clinics across Canada. Basic content analysis was used to identify key themes from the transcribed interviews. Results Barriers identified by participants fell into four categories: organizational culture, organizational resources, organizational environment and logistical challenges. Cultural challenges relate to the philosophy of IHC, organizational leadership and practitioner attitudes and beliefs. Participants also identified significant issues relating to their organization's lack of resources such as funding, compensation, infrastructure and partnerships/linkages. Environmental challenges such as the nature of a clinic's patient population and logistical issues such as the actual implementation of a research program and the applicability of research data also posed challenges to the conduct of research. Embedded research leadership, integration of personal and professional values about research, alignment of research activities and clinical workflow processes are some of the factors identified by participants that support IHC clinics' ability to conduct outcomes research. Conclusions Assessing and enhancing the broader

  15. Procuring, maintaining and using equipment: the key issues in controlling exposure to patients

    International Nuclear Information System (INIS)

    Hendra, I.R.F.

    1989-01-01

    Radiological equipment is not purpose-built for each individual application. Thus, not only are acceptance criteria directly related to the design of equipment and the quality assurance exercised during its manufacture, but also the performance, safety and reliability of equipment must feature in the requirements for procuring new equipment. In the UK this issue is dealt with under the Department of Health and Social Security Manufacturer Registration Scheme for Medical Equipment in its application to radiological equipment. Similarly the continuing reliability of equipment in service is directly related to the quality of maintenance services. This is determined largely by the manner in which such services are procured. In the UK this issue has been considered by one of four Working Parties commissioned by the South-East Thames Regional Health Authority who are the ''Centre of Responsibility'' for diagnostic imaging equipment. The report prepared from the first phase of activity of this working group describes features of a procurement specification for maintenance services and prescribes the complementary duties of contractors and customers. The use in X-ray departments of the kind of manufacturing quality system that is used by most reputable equipment manufacturers has the potential for a dramatic reduction in exposure to patients. (author)

  16. SUPPLY CHAIN MANAGEMENT – KEY FACTORS

    Directory of Open Access Journals (Sweden)

    Magdalena Daniela DINU

    2014-06-01

    Full Text Available This paper exposes Supply Chain Management by its key factors. Briefly, where the Supply Chain Management is treated as strategic part of a company then maintaining both control and influence throughout the entire supply chain are key factors and critical to success. On the other hand, finding the right partner to manage the non-strategic Supply Chains would be another key factor too. To define the most important key factors within Supply Chain Management means a deeply understanding of both Supply Chain’ s components, procedures, workflow, processes and the importance of Supply Chain Management into maximizing company's value. SCORE model able to provide solid information about measuring performance and identifying priorities within Supply Chain Management will help us to understand the key factors by analyzing its elements: Plan, Source, Make, Deliver,Return, Enable. These elements covers all the challenging areas from first to third tier of Supply Chain Management.

  17. Key Performance Indicators for Maintenance Management Effectiveness of Public Hospital Building

    Directory of Open Access Journals (Sweden)

    Farhana Omar Mardhiah

    2017-01-01

    Full Text Available Effectiveness of management in maintenance aspect holds the key element in influencing the performance of overall maintenance management. Similarly, public hospital building needs an effective maintenance management as this type of building in nature is one of the most complex issues in the field of maintenance. Improper building maintenance management adopted by the organization significantly will interrupt the overall operation of the building. Therefore, this paper is aim to identifying the key performance indicator (KPI of effectiveness of maintenance management for the public hospital building. A total of 32 set of questionnaires were distributed to the maintenance manager for each hospital in the northern region of peninsular Malaysia by using self-administration strategy. The survey answer was analyzed by performing descriptive analysis in SPSS. Overall, the result of descriptive analysis shows that all the ten factors of effectiveness of maintenance management are accepted as KPI since the mean value is at least 3.93 which classified as important and significant. The most significant factor of effectiveness of maintenance management is task planning and scheduling with the mean score of 4.35. While less significant factor is identify as maintenance approach with the value of mean score is 3.93. The both results indicates that the management need to have well-structured planning for the maintenance works and also need to embrace the exact strategy of maintenance approach in order to achieved better overall performance of maintenance management. This study may draw a standard practice for the government in assessing the performance of public facilities in terms of maintenance management.

  18. NIH Researchers Identify OCD Risk Gene

    Science.gov (United States)

    ... News From NIH NIH Researchers Identify OCD Risk Gene Past Issues / Summer 2006 Table of Contents For ... and Alcoholism (NIAAA) have identified a previously unknown gene variant that doubles an individual's risk for obsessive- ...

  19. Key policy choices in groundwater quality management

    International Nuclear Information System (INIS)

    Batie, S.S.; Diebel, P.L.

    1990-01-01

    The fundamental policy choice of who has the right to do what to whom is a pivotal issue of governance. Over the last few decades, the answer to that question has become more restrictive to those who own and use natural resources as inputs into production processes. Increasingly, the beneficiaries of new policy initiatives are those who desire higher protection of groundwater quality. With respect to groundwater management, policy design increasingly reflects such diverse interests as agriculturists, industrialists, homeowners, local government officials and state officials. Policy design is becoming complex, in part because of this diversity and in part because scientific uncertainty hampers informed policy design. No umbrella federal legislation exists for managing groundwater resources. EPA's role has been mainly an advisory one on groundwater issues. The difficulties and responsibilities of protecting groundwater thus remain with the states. For the near future, it is the states that will address key policy choices with respect to groundwater quality management issues

  20. BARI+: a biometric based distributed key management approach for wireless body area networks.

    Science.gov (United States)

    Muhammad, Khaliq-ur-Rahman Raazi Syed; Lee, Heejo; Lee, Sungyoung; Lee, Young-Koo

    2010-01-01

    Wireless body area networks (WBAN) consist of resource constrained sensing devices just like other wireless sensor networks (WSN). However, they differ from WSN in topology, scale and security requirements. Due to these differences, key management schemes designed for WSN are inefficient and unnecessarily complex when applied to WBAN. Considering the key management issue, WBAN are also different from WPAN because WBAN can use random biometric measurements as keys. We highlight the differences between WSN and WBAN and propose an efficient key management scheme, which makes use of biometrics and is specifically designed for WBAN domain.