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Sample records for hydraulic lift hl

  1. NASA HL-20 PLS Lifting Body (Mockup)

    Science.gov (United States)

    1991-01-01

    NASA HL-20 PLS Lifting Body (Mockup): The HL-20 came into use at Langley in October 1990 and is a full-scale non-flying mockup. This mockup was used for engineering studies of maintainability of the vehicle, as testing crew positions, pilot visibility and other human factors considerations.

  2. Hydraulic Lifting Mechanisms for the Erection Equipment

    Directory of Open Access Journals (Sweden)

    B. M. Novozhilov

    2016-01-01

    Full Text Available In erection equipment of space launch complexes the hydraulic lifting mechanisms (HLM are solely and exclusively used to accomplish changing the space-mission vehicle (SMV position from horizontal to the vertical one. Existing designs of lifting mechanisms are diverse, but all of them basically contain a basic mechanism comprising one hydro-cylinder. With increasing SMV size and weight a task to design the more complicated lifting mechanisms, comprising more kinematic links and using several hydro-cylinders becomes urgent.The article conducts a detailed analysis of the basic HLM schemes and defines the features of their arrangement in erection equipment. Gives basic calculation relationships, allowing us to determine design parameters of mechanisms for stationary and transport units. Via examples of available erection equipment shows the embodiment of lifting mechanisms using basic schemes.The ways for development of HLM schemes to erect a SMV of the large size and weight are shown. Two options of the double-cylinder HLM are described. Both schemes are based on dividing a lift cycle into two parts, in each of which only one of the cylinders is in operation. The first option contains an additional, intermediate boom, with respect to which the main boom is erected. In such a mechanism the cylinders start running sequentially: at first, one of the cylinders erects the intermediate boom, then the other cylinder does the main one. The second HLM embodiment comprises a single carrier boom with the swing arm, which allows to swing the boom at a certain angle of less than 90 ° using one of the cylinders, also sequentially operating. The second cylinder allows the boom to fall into vertical position. Such schemes can reduce a stroke length of used hydraulic cylinders, which are the most expensive devices of the lifting mechanism.The analysis results are of interest to designers of erection equipment for the space launch complexes.

  3. The effect of hydraulic lift on organic matter decomposition, soil nitrogen cycling, and nitrogen acquisition by a grass species.

    Science.gov (United States)

    Armas, Cristina; Kim, John H; Bleby, Timothy M; Jackson, Robert B

    2012-01-01

    Hydraulic lift (HL) is the passive movement of water through plant roots, driven by gradients in water potential. The greater soil-water availability resulting from HL may in principle lead to higher plant nutrient uptake, but the evidence for this hypothesis is not universally supported by current experiments. We grew a grass species common in North America in two-layer pots with three treatments: (1) the lower layer watered, the upper one unwatered (HL), (2) both layers watered (W), and (3) the lower layer watered, the upper one unwatered, but with continuous light 24 h a day to limit HL (no-HL). We inserted ingrowth cores filled with enriched-nitrogen organic matter ((15)N-OM) in the upper layer and tested whether decomposition, mineralization and uptake of (15)N were higher in plants performing HL than in plants without HL. Soils in the upper layer were significantly wetter in the HL treatment than in the no-HL treatment. Decomposition rates were similar in the W and HL treatments and lower in no-HL. On average, the concentration of NH(4)(+)-N in ingrowth cores was highest in the W treatment, and NO(3)(-)-N concentrations were highest in the no-HL treatment, with HL having intermediate values for both, suggesting differential mineralization of organic N among treatments. Aboveground biomass, leaf (15)N contents and the (15)N uptake in aboveground tissues were higher in W and HL than in no-HL, indicating higher nutrient uptake and improved N status of plants performing HL. However, there were no differences in total root nitrogen content or (15)N uptake by roots, indicating that HL affected plant allocation of acquired N to photosynthetic tissues. Our evidence for the role of HL in organic matter decomposition and nutrient cycling suggests that HL could have positive effects on plant nutrient dynamics and nutrient turnover.

  4. Efflux of hydraulically lifted water from mycorrhizal fungal hyphae during imposed drought

    Science.gov (United States)

    Querejeta, José Ignacio; Allen, Michael F

    2008-01-01

    Apart from improving plant and soil water status during drought, it has been suggested that hydraulic lift (HL) could enhance plant nutrient capture through the flow of mineral nutrients directly from the soil to plant roots, or by maintaining the functioning of mycorrhizal fungi. We evaluated the extent to which the diel cycle of water availability created by HL covaries with the efflux of HL water from the tips of extramatrical (external) mycorrhizal hyphae, and the possible effects on biogeochemical processes. Phenotypic mycorrhizal fungal variables, such as total and live hyphal lengths, were positively correlated with HL efflux from hyphae, soil water potential (dawn), and plant response variables (foliar 15N). The efflux of HL water from hyphae was also correlated with bacterial abundance and soil enzyme activity (P), and the moistening of soil organic matter. Such findings indicate that the efflux of HL water from the external mycorrhizal mycelia may be a complementary explanation for plant nutrient acquisition and survival during drought. PMID:19704776

  5. Predictive Maintenance of Hydraulic Lifts through Lubricating Oil Analysis

    OpenAIRE

    Stamatios S. Kalligeros

    2013-01-01

    This article examines the possibility of measuring lift maintenance through analysis of used hydraulic oil. Hydraulic oils have proved to be a reliable indicator for the maintenance performed on elevators. It has also been proved that the end users or the maintenance personnel do not always conform to the instructions of the elevators’ hydraulic machine manufacturer. Furthermore, by examining the proportion of the metals, an estimation of the corrosion and the wear resistance of the joined mo...

  6. Predictive Maintenance of Hydraulic Lifts through Lubricating Oil Analysis

    Directory of Open Access Journals (Sweden)

    Stamatios S. Kalligeros

    2013-12-01

    Full Text Available This article examines the possibility of measuring lift maintenance through analysis of used hydraulic oil. Hydraulic oils have proved to be a reliable indicator for the maintenance performed on elevators. It has also been proved that the end users or the maintenance personnel do not always conform to the instructions of the elevators’ hydraulic machine manufacturer. Furthermore, by examining the proportion of the metals, an estimation of the corrosion and the wear resistance of the joined moving parts can be observed. Additionally, the presence of chlorine and calcium in hydraulic oils demonstrates their function in a highly corrosive environment.

  7. Investigations of hydraulic operating conditions of air lift pump with three types of air-water mixers

    Directory of Open Access Journals (Sweden)

    Kalenik Marek

    2015-03-01

    Full Text Available Investigations of hydraulic operating conditions of air lift pump with three types of air-water mixers. The paper presents the analysis of results of the investigations concerning the influence of various constructive solutions of the air-water mixers on hydraulic operating conditions of the air lift pump. The scope of the investigations encompassed the determination of characteristics of delivery head and delivery rate for three types of air-water mixers applied in the constructed air lift pump. Using the obtained results, the efficiency of the three types of air-water mixers applied in this air lift pump was determined. The analysis was carried out and there was checked whether the improved analytical Stenning-Martin model can be used to design air lift pumps with the air-water mixers of these types. The highest capacity in the water transport was reached by the air lift pump with the 1st type air-water mixer, the lowest one – with the 3rd type air-water mixer. The water flow in the air lift pump increases along with the rise in the air flow. The lower are the hydraulic losses generated during flow of the air flux by the air-water mixer, the higher is the air lift pump capacity. Along with the rise in the water delivery head, the capacity of the air lift pump decreases. The highest efficiency is reached by the air lift pump with the 1st type air-water mixer, the lowest – with the 3st type air-water mixer. The efficiency of the air lift pump for the three investigated types of air-water mixers decreases along with the rise in air flow rate and water delivery head. The values of submergence ratio (h/L of the delivery pipe, calculated with the use of the improved analytical Stenning-Martin model, coincide quite well with the values of h/L determined from the measurements.

  8. Hydraulic lift in a neotropical savanna: experimental manipulation and model simulations

    Science.gov (United States)

    Fabian G. Scholz; Sandra J. Bucci; William A. Hoffmann; Frederick C. Meinzer; Guillermo Goldstein

    2010-01-01

    The objective of this study was to assess the magnitude of hydraulic lift in Brazilian savannas (Cerrado) and to test the hypothesis that hydraulic lift by herbaceous plants contributes substantially to slowing the decline of water potential and water storage in the upper soil layers during the dry season. To this effect, field observations of soil water content and...

  9. Two-axis hydraulic joint for high speed, heavy lift robotic operations

    Energy Technology Data Exchange (ETDEWEB)

    Vaughn, M.R.; Robinett, R.D.; Phelan, J.R.; VanZuiden, D.M.

    1994-04-01

    A hydraulically driven universal joint was developed for a heavy lift, high speed nuclear waste remediation application. Each axis is driven by a simple hydraulic cylinder controlled by a jet pipe servovalve. Servovalve behavior is controlled by a force feedback control system, which damps the hydraulic resonance. A prototype single joint robot was built and tested. A two joint robot is under construction.

  10. Hydraulic lift as a determinant of tree-grass coexistence on savannas.

    Science.gov (United States)

    Yu, Kailiang; D'Odorico, Paolo

    2015-09-01

    The coexistence of woody plants and grasses in savannas is determined by a complex set of interacting factors that determine access to resources and demographic dynamics, under the control of external drivers and vegetation feedbacks with the physical environment. Existing theories explain coexistence mainly as an effect of competitive relations and/or disturbances. However, theoretical studies on the way facilitative interactions resulting from hydraulic lift affect tree-grass coexistence and the range of environmental conditions in which savannas are stable are still lacking. We investigated the role of hydraulic lift in the stability of tree-grass coexistence in savannas. To that end, we developed a new mechanistic model that accounts for both competition for soil water in the shallow soil and fire-induced disturbance. We found that hydraulic lift favors grasses, which scavenge the water lifted by woody plants. Thus, hydraulic lift expands (at the expenses of woodlands) the range of environmental conditions in which savannas are stable. These results indicate that hydraulic lift can be an important mechanism responsible for the coexistence of woody plants and grasses in savannas. Grass facilitation by trees through the process of hydraulic lift could allow savannas to persist stably in mesic regions that would otherwise exhibit a forest cover.

  11. Hydraulic ram —a device lifting water without conventional energy

    Institute of Scientific and Technical Information of China (English)

    MaChi; HuYingde

    2003-01-01

    In the southern part of China, due to the rich rainfalls and favourably topographical landscape, there is abundant hydraulic energy resources contained in the countless small streams and rivers in the mountainous and semi-mountainous areas. Besides the small hydro power generation which transfers the potential energy to the electrical power, there is other technology available to utilise the potential energy directly for the water lifting in the irrigation and decentralised do-mestic water supply in the village level. This paper introduces the basic principle of the hydraulic ram op-eration and describes the applicable opportunities for the hydraulic ram.

  12. The hydraulic lifting system for the main magnets of CYCIAE-30 cyclotron

    CERN Document Server

    Zhao Zhen Lu; Chen Rong Fan; Chu Cheng Jie

    2002-01-01

    The oil-line structure, control system and their working principles of the hydraulic lifting system for the main magnets of CYCIAE-30 cyclotron are introduced. The six years practice proves that the specification of the system matches the requirements: the oil cylinder maximum stroke of 850 mm, the eight slot positioning dowels repositioning accuracy of +-0.01 mm, the two oil cylinders moving in step accuracy of 5-10 mm. The system is safe, reliable and easy to be operated

  13. Thermal-hydraulic analysis of the HL-2M divertor using an homogeneous equilibrium model

    Science.gov (United States)

    Lu, Yong; Cai, Lijun; Liu, Yuxiang; Liu, Jian; Yuan, Yinglong; Zheng, Guoyao; Liu, Dequan

    2017-09-01

    The heat flux of the HL-2M divertor would reach 10 MW m-2 or more at the local area when the device operates at high parameters. Subcooled boiling could occur at high thermal load, which would be simulated based on the homogeneous equilibrium model. The results show that the current design of the HL-2M divertor could withstand the local heat flux 10 MW m-2 at a plasma pulse duration of 5 s, inlet coolant pressure of 1.5 MPa and flow velocity of 4 m s-1. The pulse duration that the HL-2M divertor could withstand is closely related to the coolant velocity. In addition, at the time of 2 min after plasma discharge, the flow velocity decreased from 4 m s-1 to 1 m s-1, and the divertor could also be cooled to the initial temperature before the next plasma discharge commences.

  14. Hydraulic lift and tolerance to salinity of semiarid species: consequences for species interactions.

    Science.gov (United States)

    Armas, Cristina; Padilla, Francisco M; Pugnaire, Francisco I; Jackson, Robert B

    2010-01-01

    The different abilities of plant species to use ephemeral or permanent water sources strongly affect physiological performance and species coexistence in water-limited ecosystems. In addition to withstanding drought, plants in coastal habitats often have to withstand highly saline soils, an additional ecological stress. Here we tested whether observed competitive abilities and C-water relations of two interacting shrub species from an arid coastal system were more related to differences in root architecture or salinity tolerance. We explored water sources of interacting Juniperus phoenicea Guss. and Pistacia lentiscus L. plants by conducting physiology measurements, including water relations, CO2 exchange, photochemical efficiency, sap osmolality, and water and C isotopes. We also conducted parallel soil analyses that included electrical conductivity, humidity, and water isotopes. During drought, Pistacia shrubs relied primarily on permanent salty groundwater, while isolated Juniperus plants took up the scarce and relatively fresh water stored in upper soil layers. As drought progressed further, the physiological activity of Juniperus plants nearly stopped while Pistacia plants were only slightly affected. Juniperus plants growing with Pistacia had stem-water isotopes that matched Pistacia, unlike values for isolated Juniperus plants. This result suggests that Pistacia shrubs supplied water to nearby Juniperus plants through hydraulic lift. This lifted water, however, did not appear to benefit Juniperus plants, as their physiological performance with co-occurring Pistacia plants was poor, including lower water potentials and rates of photosynthesis than isolated plants. Juniperus was more salt sensitive than Pistacia, which withstood salinity levels similar to that of groundwater. Overall, the different abilities of the two species to use salty water appear to drive the outcome of their interaction, resulting in asymmetric competition where Juniperus is negatively

  15. Hydraulic model of a gas-lift bioreactor with flocculating yeast

    Energy Technology Data Exchange (ETDEWEB)

    Roca, E. [Chemical Engineering Dept., Univ. of Santiago de Compostela (Spain); Ghommidh, C. [G.B.S.A. Microbiologie et Biochimie Industrielle. Univ. Montpellier 2, 34 Montpellier (France); Navarro, J.M. [G.B.S.A. Microbiologie et Biochimie Industrielle. Univ. Montpellier 2, 34 Montpellier (France); Lema, J.M. [Chemical Engineering Dept., Univ. of Santiago de Compostela (Spain)

    1995-04-01

    The hydraulic model of a gas lift bioreactor, during a continuous alcoholic fermentation by using a strongly flocculating yeast, is analysed. Sucrose at two different concentrations (50 and 100 g/l) was used as substrate and the dilution rate for all the experiments was 1 h{sup -1}. The biomass concentrations were between 85 and 110 g dry weight/l. A stimulus response technique was used to obtain the Residence Time Distribution curves, a pulse of a lactose solution being used as the tracer. Mixing time was determined by means of the response to a pulse of an acid tracer. These experiments were carried out by using an on-line data-acquisition system. The bioreactor behaviour is completely homogeneous, except for high substrate and biomass concentrations. A two parameters combined model is necessary, in this case, to fit the experimental data. Mixing times are very low, in the order of 10 seconds. (orig.)

  16. Calculation Method for Effect of Silt Sediment on Lifting Force of HydraulicGate

    Institute of Scientific and Technical Information of China (English)

    Gao Shizhao; Xu Guobin; Wang Mingbin

    2015-01-01

    In this paper, silt sediment is considered to be Bingham body, which is made up of coarse and fine parti-cles in front of a hydraulic gate. The coarse and fine particles provide friction and shear stress in the course of opening the gate. They constitute together the adhesion force of the sediment. Based on this viewpoint, this paper putsforward a formula for the effect of silt sediment on the lifting force. The formula includes gate weight, down-suction force, sealing rubber friction, plus-weight, water-column pressure, plus-silted-sediment weight and rolling(or sliding)-bearing friction. Finally, the verification results show that the formula has certain reliability and the calculation accu-racy can meet the need of practical engineering.

  17. The ability on hydraulic-lift from deeper rooted plants with a phytoassay of rice (Oryza sativa L.)

    OpenAIRE

    2009-01-01

    Hydraulic lift(HL), the exudation of water from root system of deeper rooted plants under soil desiccated conditions is considered as a potential irrigation system in drought areas. The ability of HL in sorghum(Sorghum bicolor(L.)Moench)was evaluated by a split root experiment with mixed-cropped rice(Oryza sativa L.)as an indicator plant for phytoassay. Growth parameters of rice and soil water conditions are measured after withholding irrigation with or without sorghum root connection between...

  18. Regional characterisation of hydraulic properties of rock using air-lift data

    Science.gov (United States)

    Wladis, David; Gustafson, Gunnar

    Hydrogeologic studies are commonly data-intense. In particular, estimations of hydraulic properties of hard rock often require large amounts of data. In many countries, large quantities of hydrogeologic data have been collected and archived over the years. Therefore, the use of existing data may provide a cost-efficient alternative to collecting new data in early stages of hydrogeologic studies, although the available data may be considered imprecise. Initially, however, the potential usefulness, i.e., the expected accuracy, of the available data in each specific case must be carefully examined. This study investigates the possibilities of obtaining estimates of transmissivity from hard-rock air-lift data in Sweden within an order of magnitude of results obtained from high-quality injection-test data. The expected accuracy of the results was examined analytically and by means of statistical methods. The results were also evaluated by comparison with injection-test data. The results indicate that air-lift data produce estimates of transmissivity within an order of magnitude compared to injection-test data in the studied examples. The study also shows that partial penetration and hydrofracturing may only affect the estimations approximately half an order of magnitude. Thus, existing data may provide a cost-efficient alternative to collection of new data in early stages of hydrogeologic studies. Résumé Les études hydrogéologiques reposent en général sur un nombre important de données. En particulier, l'estimation des propriétés hydrauliques des roches indurées exige souvent un grand nombre de données. Dans de nombreuses régions, des données hydrogéologiques très nombreuses ont été recueillies et archivées depuis longtemps. C'est pourquoi le recours à des données existantes peut être une alternative intéressante en termes de coût par rapport à l'obtention de nouvelles données dans les premières étapes des études hydrogéologiques, même si

  19. HL-20 at Langley

    Science.gov (United States)

    1992-01-01

    The NASA Langley Research Center lifting body, called the HL-20, is shown here in front of the hangar. The HL-20 was one of two concepts considered by NASA as a type of Personnel Launch System (PLS). In essence, it would serve as a space taxi to and from the space station. The full scale engineering model is 29.5 feet long, and 23.5 feet across the wingspan.

  20. Design of Hydraulic Protection Equipment Served the Disabled Weight-lifting%残疾人举重液压伺服保护装置设计

    Institute of Scientific and Technical Information of China (English)

    汪功明

    2015-01-01

    A kind of hydraulic protection equipment served the disabled weight⁃lifting was designed. The equipment consisted of guide rail, hydraulic following unit and hydraulic lifting unit. It mainly depended on hydraulic servo theory to work. The technical pro⁃posal and the model designs of the core structure of the equipment were stated.%设计一种残疾人举重保护装置,该装置由导轨、液压跟随单元、液压托举单元等三部分组成,主要依据液压伺服原理工作。阐述了该装置的技术方案,并对装置的核心结构做了选型设计。

  1. HL-20 Wax Model

    Science.gov (United States)

    1993-01-01

    A numerically machined wax pattern of the NASA HL-20 orbital re-entry lifting body was cut from a CAD/CAM file. This nine-inch wax model was later used in a lost wax investment casting process to replicate the pattern in ceramic for wind-tunnel aero-heating studies

  2. Hydraulics.

    Science.gov (United States)

    Decker, Robert L.; Kirby, Klane

    This curriculum guide contains a course in hydraulics to train entry-level workers for automotive mechanics and other fields that utilize hydraulics. The module contains 14 instructional units that cover the following topics: (1) introduction to hydraulics; (2) fundamentals of hydraulics; (3) reservoirs; (4) lines, fittings, and couplers; (5)…

  3. Effect of Hydraulic Retention Time on Nitrification in an AirLift Biological Reactor

    Directory of Open Access Journals (Sweden)

    Furtado A.A.L.

    1998-01-01

    Full Text Available The occurrence of nitrogenous compounds in industrial effluents at concentration levels above legal limits, is a well-known and serious pollution problem for the receiving body. The biological process for the removal of these substances, commonly referred to as ammoniacal nitrogen, is known as nitrification. Bacteria involved are mainly of the genuses Nitrosomonas and Nitrobacter. The aim of the present work was to study the effect of the hydraulic retention time (HRT on the efficiency of ammonia removal from a petroleum refinery effluent using activated carbon particles as a biofilm support in an airlift bioreactor. The experiments were carried out using HRTs, equal to six, eight and ten hours. The results show that HRT equal to 8 and 10 hours were enough to reduce ammoniacal nitrogen concentration to levels below permited legal limits (5mg/L NH3-N. The reactor nitrifying performance was maximized at 85% removal of ammoniacal nitrogen, for a HRT equal to 10 hours.

  4. 双向液压锁新型车载液压尾板系统的研究与设计%Research and Design of A New Type of Vehicle Hydraulic Lift-tail System Using Hydraulic Lock

    Institute of Scientific and Technical Information of China (English)

    赵丽华; 李喜玲; 高和平

    2016-01-01

    车载液压尾板在现代汽车装载作业中被广泛应用。由于汽车车底空间有限,不能承受太大的重量,所以整个液压尾板的尺寸与重量成为尾板设计过程中首先要考虑的问题。现在市面上大部分液压尾板采用两个举升油缸、两个翻转油缸和一个平衡油缸的结构型式控制尾板的举升与翻转,油缸较多,使整个尾板的重量增加,且传动结构复杂。本文将介绍一种新式液压尾板设计思路,省去平衡缸,且举升缸和翻转缸分别用一个,举升缸采用二级伸缩油缸控制尾板的翻转与举升,液压系统中加装液压锁。该传动机构简单实用,在减小了尾板尺寸与重量的同时,提升了整套设备的安全性与可靠性。%Vehicle hydraulic lift-tail has been applied in the truck loading operation . Due to the space of the car’s bottom is limited,it can’t bear too much,so the size and weight of the hydraulic lift-tail become the first issue to be consided in the process of design. Now on the market,most of the hydraulic lift-tail works with two lifting oil cylinder, two overturning oil cylinder and one balance cylinder to f control the lift-tail’s lifting and overturning, cylinder is too many, make the whole weight of the lift-tail increase,and the transmission structure is too complex. This paper will introduce a new design of the hydraulic lift-tail,save the balance cylinder,only use one lifting cylinder and one overturning cylinder, and use the secondary scaling cylinder to control the overturning and lifting of the lift-tail ,the transmission mechanism is simple and practical ,in this way,it can achieve the purpose of reducing the size and weight of the hydraulic lift-tail and improving the security and reliability of the whole equipment.

  5. Effects of hydraulic retention time and nitrobenzene concentration on the performance of sequential upflow anaerobic filter and air lift reactors in treating nitrobenzene-containing wastewater

    DEFF Research Database (Denmark)

    Wu, Jinhua; Chen, Guocai; Gu, Jingjing;

    2014-01-01

    Sequential upflow anaerobic filter (UAF)/air lift (ALR) reactors were employed to investigate the effects of hydraulic retention time (HRT) and nitrobenzene (NB) concentration on treatment of NB-containing wastewater. The results showed that NB was effectively reduced to aniline (AN) with glucose...... and the influent NB concentration increased from 400 to 800 mg l super(-1), respectively. The results showed that sequential UAF/ALR system can be operated at low HRTs and high NB concentrations without significantly affecting the removal efficiency of NB in the reactor system. The UAF/ALR system can provide...... an effective yet low cost method for treatment of NB-containing industrial wastewater....

  6. 液压起吊千斤在液压支架组装站上的应用%Applications of Hydraulic lifting jack in hydraulic support assembly on the station

    Institute of Scientific and Technical Information of China (English)

    刘长青

    2016-01-01

    The support demolition of 15112 working face of Yangquan Coal Si Jia Zhuang company, lifting weight reached 40t, the pneumatic leading chain in the assembly station can’t meet the requirements, so the use of four hydraulic lifting jack for the entire frame lifting, is successful for the first time trial, compared to the traditional pneumatic chain lifting safety factor and the work efficiency is high , which provide strong technical support for the equipment safe and smooth demolition.%阳煤寺家庄公司15112工作面拆运支架时,起吊重量达到40t,组装站内的风动导链起吊不能满足要求,因此采用在组装站内安装4根起吊液压千斤进行整架起吊,首次试验获得成功,较以往风动导链起吊安全系数高,作业效率高,给此次设备拆除工程的安全顺利进行提供有力的技术保障。

  7. HL-20 Model

    Science.gov (United States)

    1990-01-01

    Robert Vess, a lecturer in mechanical and aerospace engineering at North Carolina State Univeristy, Raleigh, N.C., installs the window flange trim on a full-size engineering model of the HL-20 lifting body for the NASA Langley Research Center. The model, which is approximately 29 feet long, was built by NCSU and North Carolina Agricultural and Technical Univeristy, Greensboro, N.C., for studying crew seating arrangements, habitability, equipment layout, crew ingress and egress, and maintance and handling operations. The studies will take place at Langley and at the NASA Johnson Space Center, Houston, Texas.

  8. Breast lift

    Science.gov (United States)

    Mastopexy; Breast lift with reduction; Breast lift with augmentation ... enlargement with implants) when they have a breast lift. ... it for medical reasons. Women usually have breast lifts to lift sagging, loose breasts. Pregnancy, breastfeeding, and ...

  9. Hydraulic structures

    CERN Document Server

    Chen, Sheng-Hong

    2015-01-01

    This book discusses in detail the planning, design, construction and management of hydraulic structures, covering dams, spillways, tunnels, cut slopes, sluices, water intake and measuring works, ship locks and lifts, as well as fish ways. Particular attention is paid to considerations concerning the environment, hydrology, geology and materials etc. in the planning and design of hydraulic projects. It also considers the type selection, profile configuration, stress/stability calibration and engineering countermeasures, flood releasing arrangements and scouring protection, operation and maintenance etc. for a variety of specific hydraulic structures. The book is primarily intended for engineers, undergraduate and graduate students in the field of civil and hydraulic engineering who are faced with the challenges of extending our understanding of hydraulic structures ranging from traditional to groundbreaking, as well as designing, constructing and managing safe, durable hydraulic structures that are economical ...

  10. HL-10 on lakebed with pilot Major Jerauld R. Gentry

    Science.gov (United States)

    1968-01-01

    Pilot Major Jerauld R. Gentry stands in front of the HL-10 Lifting Body. Gentry was the Air Force project pilot for the HL-10 while it was making the early glide and powered flights in 1968 following its modification. He made a total of nine flights in the vehicle. For his work on the HL-10, Gentry was awarded the Harmon International Trophy for his outstanding contribution to the science of flying. He later became the Air Force pilot for the X-24A. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and

  11. Study on mode of on-off operation of water filling-emptying Valve for hydraulic floating ship lift%水力浮动式升船机充泄水阀门启闭方式研究

    Institute of Scientific and Technical Information of China (English)

    张蕊; 吴一红; 章晋雄; 张东

    2011-01-01

    Based on the operation principle of the hydraulic floating ship lift, a conceptual model for its water conveyance system, floating balancing weight-ship lift chamber system is established, and then the on-off operation mode of the water fillingemptying is studied with the numerical computations. The results show that the hydraulic control of the water filling and emptying valve is the key-link to ensure the stable operation and accurate positioning of the hydraulic floating ship lift. Through an intermittent on-off operation mode of the valve, the operation of ship lift chamber can be effectively controlled to meet the requirement concerned by means of setting an appropriate opening of the valve before the chamber being in and out of water, controlling water conveyance flow rate of the system and lowering the speeds of the chamber being in and out of water.%根据水力浮动式升船机的工作原理,研究建立了输水系统、平衡重浮筒--承船厢系统的概化模型,并采用数值计算方法研究了充泄水阀门合理的启闭方式.结果表明,充泄水阀门的水力控制是保证水力浮动式升船机运行稳定和准确停位的关键.通过采用阀门间歇开启方式,在承船厢入、出水前通过设定合适的阀门开度,控制系统输水流量,降低承船厢入、出水的速度,可以有效地控制承船厢运行满足要求.

  12. Evidence of hydraulic lift for pre-rainy season leaf out and dry-season stem water enrichment in Sclerocarya birrea, a tropical agroforestry tree

    Science.gov (United States)

    Ceperley, Natalie; Mande, Theophile; Rinaldo, Andrea; Parlange, Marc B.

    2014-05-01

    We use stable isotopes of water as tracers to follow water use by five Sclerocarya birrea trees in a catchment in South Eastern Burkina Faso interspersed with millet fields, gallery forest, Sudanian savanna, and fallow fields. Isotopic ratios were determined from water extracted from stems of the trees and sub-canopy soil of two of them, while nearby ground water, precipitation, and surface water was sampled weekly. A unique configuration of sensors connected with a wireless sensor network of meteorological stations measured sub-canopy shading, the temperature and humidity in the canopy, through-fall, and soil moisture under two of the trees. Both water extracted from sap and water extracted from soil is extremely enriched in the dry season, but drop to levels close to the ground water in February or March, which coincides with the growth of leaves. Dates of leaf out were confirmed by changes in δDH and δO18 concentrations of water, photographic documentation & pixel analysis, and analysis of sub-canopy radiation and proceeded the rise in humidity and flow that was later detected in the sub-canopy soil, the trunk of the tree (sap-flow), and atmosphere (canopy VPD). Examination of the isotopic signature suggests that size of tree plays an important role in duration and timing of this leaf-out as well as the degree of enrichment during the peak of the dry season. Further examination of the isotopic signatures of the roots suggested that the trees are performing hydraulic redistribution, or lifting the ground water and "sharing it" with the soil in the rooting zone in the dry season. The enriched level of xylem in this case is a product of water loss, and enrichment, along the travel path of the water from the roots to the tip of the stem, as evidenced by the variation according to size of tree. Vapor pressure deficit, soil water, and soil moisture interactions support this picture of interacting controls, separate from hydrologic triggers on the water movement in

  13. Tornado lift

    CERN Document Server

    Ivanchin, Alexander

    2010-01-01

    It is shown that one of the causes for tornado is Tornado Lift. At increasing vortex diameter its kinetic energy decreases to keep the moment of momentum constant. A kinetic energy gradient of such vortex is Tornado Lift. Evaluation shows that contribution of Tornado Lift in air lifting in a tornado is comparable to buoyancy according to the order of magnitude.

  14. Lifting operations and lifting equipment

    NARCIS (Netherlands)

    Douwes, M.

    2013-01-01

    Lifting operations are inherent to many occupations in the construction industry. They can be performed manually or using lifting equipment. Both manual lifting and mechanical lifting operations can put construction workers at great risk of injury or health symptoms causing sick leave or disability.

  15. Preliminary structural evaluation and design of the HL-20

    Science.gov (United States)

    Bush, Lance B.; Wahls, Deborah M.; Robinson, James C.

    1993-02-01

    Several concepts have been proposed to meet the requirements of a Personnel Launch System. A lifting body concept, the HL-20, was designed at NASA Langley Research Center. A structural analysis of a proposed HL-20 configuration with a cylindrical pressurized crew cabin is presented in this paper. Loads for the vehicle are assembled from mission loading conditions such as abort, on-orbit pressurization, blast overpressure, aerodynamic maneuver, and touchdown. The critical loading conditions are identified and resultant loads mapped onto the structure in order to review the effects of the mission loading conditions. The HL-20 structural concept is sized for the mission loads and the resulting structural weights are calculated.

  16. Buttock Lift

    Science.gov (United States)

    Tests and Procedures Buttock lift By Mayo Clinic Staff A buttock lift is a cosmetic surgical procedure to improve the appearance of the buttocks. It's ... part of a belt lipectomy or lower body lift to contour the buttocks, groin, thighs and abdomen. ...

  17. 摇摆台升沉运动液压系统设计%Design of Hydraulic Lift System for Swing Bench

    Institute of Scientific and Technical Information of China (English)

    张瑜; 王红艳; 沈延康; 田魁岳; 鲁士军

    2012-01-01

    This swing bench(oscillating table) is a precise piece of equipment for physical simulation that it can simulate a boat oscillating under various sea water conditions. The text introduces how the up-down motion hydraulic system was designed for the oscillating table, and how to analyze the oil-pneumatic spring-balance system and the hydraulic servo system which was consisted of bag-type accumulator and hydraulic cylinders while pointing out superiorities of the system's minimized inertial impact, lower power drive rate, and lower cost.%摇摆试验台(摇摆台)是一种高精度物理仿真设备,它可以模拟舰船在不同海况下的摇摆运动.介绍摇摆台的升沉运动液压系统的设计,对囊式蓄能器和液压缸组成的油气弹簧平衡系统和液压伺服系统进行分析.指出此系统在减小惯性冲击,降低系统驱动功率,降低成本方面的优势.

  18. HL-LHC Accelerator

    CERN Document Server

    Zimmermann, F

    2013-01-01

    The tentative schedule, key ingredients, as well as progress of pertinent R&D and component prototypes for the LHC luminosity upgrade, "HL-LHC," are reviewed. Also alternative scenarios based on performance-improving consolidations (PICs) instead of a full upgrade are discussed. Tentative time schedules and expected luminosity evolutions for the different scenarios are sketched. The important role of HL-LHC development as a step towards a future HE-LHC or VHE-LHC is finally highlighted. Presented at "Higgs & Beyond" Conference Tohoku University, Sendai 7 June 2013.

  19. Eyelid lift

    Science.gov (United States)

    Eyelid lift surgery is done to repair sagging or drooping upper eyelids ( ptosis ). The surgery is called blepharoplasty. Sagging or drooping eyelids occur with increasing age. Some people are born with ...

  20. HL-10 on lakebed with Jerauld R. Gentry, Peter Hoag, John A. Manke, and Bill Dana

    Science.gov (United States)

    1969-01-01

    The four principal HL-10 pilots are seen here with the lifting body aircraft. They are, left to right; Air Force Major Jerauld R. Gentry, Air Force test pilot Peter Hoag, and NASA pilots John A. Manke and Bill Dana. All are wearing the pressure suits needed for flying above 50,000 feet. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2-F2/F3

  1. Hydraulic hoist-press

    Energy Technology Data Exchange (ETDEWEB)

    Babayev, Z.B.; Abashev, Z.V.

    1982-01-01

    The efficiency expert of the Angrenskiy production-technological administration of the production association Sredazugol A. V. Bubnov has suggested a hydraulic hoist-press for repairing road equipment which is a device consisting of lifting mechanism, press and test stand for verifying the high pressure hoses and pumps.

  2. Water Hydraulic Systems

    DEFF Research Database (Denmark)

    Conrad, Finn

    2005-01-01

    The paper presents research results using IT-Tools for CAD and dynamic modelling, simulation, analysis, and design of water hydraulic actuators for motion control of machines, lifts, cranes and robots. Matlab/Simulink and CATIA are used as IT-Tools. The contributions include results from on-going...

  3. High speed photographic analysis of characteristics of large particle movement in hydraulic lifting system%水力提升管道大颗粒运动特性的高速摄影分析

    Institute of Scientific and Technical Information of China (English)

    王英杰; 阳宁; 金星

    2012-01-01

    In order to improve hydraulic transportation pipeline safety, the characteristics of large particle movement in a hydraulic lifting system are investigated by using high speed photography. The movement of particles and particle swarms were observed. The single particle trajectory, particle swarm distribution, the axial velocity of particles and the radial velocity of particles were obtained through digital image processing technology. In addition, this paper analyzes the influence of particle size on the flotating velocity. The study shows that the single particle presents spiral movement state basically; particle swarms are distributed mainly in the center of the pipe; the axial velocity of a particle presents parabolic distribution along the diametric direction, inversely proportional to the particle size; in contrast, the radial velocity of coarse particles presents normal distribution.%为提高管道水力输送安全性,本文利用高速摄影技术对水力提升系统中大颗粒的运动规律进行了试验研究,观察了颗粒及颗粒群体的运动状态.通过数字图像处理技术,得到了单颗粒的运动轨迹和颗粒群分布规律,同时获得了颗粒轴向速度、径向速度等各种运动参散,并分析了颗粒粒径对其轴向速度的影响.研究发现单颗粒基本上属于螺旋式上升的状态;颗粒群主要集中于管道的中心;颗粒的轴向速度在沿管径的分布类似于抛物线分布,大小基本上与颗粒的粒径成反比;径向速度沿管径基本符合正态分布.

  4. HL-LHC alternatives

    CERN Document Server

    Tomás, R; White, S

    2014-01-01

    The HL-LHC parameters assume unexplored regimes for hadron colliders in various aspects of accelerator beam dynamics and technology. This paper reviews three alternatives that could potentially improve the LHC performance: (i) the alternative filling scheme 8b+4e, (ii) the use of a 200 MHz RF system in the LHC and (iii) the use of proton cooling methods to reduce the beam emittance (at top energy and at injection). The alternatives are assessed in terms of feasibility, pros and cons, risks versus benefits and the impact on beam availability.

  5. Water Hydraulic Systems

    DEFF Research Database (Denmark)

    Conrad, Finn

    2005-01-01

    The paper presents research results using IT-Tools for CAD and dynamic modelling, simulation, analysis, and design of water hydraulic actuators for motion control of machines, lifts, cranes and robots. Matlab/Simulink and CATIA are used as IT-Tools. The contributions include results from on......-going research projects on fluid power and mechatronics based on tap water hydraulic servovalves and linear servo actuators and rotary vane actuators for motion control and power transmission. Development and design a novel water hydraulic rotary vane actuator for robot manipulators. Proposed mathematical...... modelling, control and simulation of a water hydraulic rotary vane actuator applied to power and control a two-links manipulator and evaluate performance. The results include engineering design and test of the proposed simulation models compared with IHA Tampere University’s presentation of research...

  6. 21st century space transportation system design approach - HL-20 personnel launch system

    Science.gov (United States)

    Stone, Howard W.; Piland, William M.

    1993-10-01

    This article provides an introduction to and overview of the research that was conducted on the HL-20 lifting body. The concept has been defined as an option for a personnel launch system (PLS) that is intended to carry six to eight Space Station Freedom crew persons. In this role the HL-20 will complement the Space Shuttle operation and ensure the ability to transport people to and from Earth orbit after the year 2000. The research covers a broad range of disciplines, including aerodynamics, aerodynamic heating and thermal protection systems, structural design, subsystem definition, trajectory and guidance system development for entry and abort, production and operations, and human factors. This article also presents the lifting-body heritage, design features of the concept, and HL-20/PLS mission requirements.

  7. Tree Hydraulics: How Sap Rises

    Science.gov (United States)

    Denny, Mark

    2012-01-01

    Trees transport water from roots to crown--a height that can exceed 100 m. The physics of tree hydraulics can be conveyed with simple fluid dynamics based upon the Hagen-Poiseuille equation and Murray's law. Here the conduit structure is modelled as conical pipes and as branching pipes. The force required to lift sap is generated mostly by…

  8. Tree Hydraulics: How Sap Rises

    Science.gov (United States)

    Denny, Mark

    2012-01-01

    Trees transport water from roots to crown--a height that can exceed 100 m. The physics of tree hydraulics can be conveyed with simple fluid dynamics based upon the Hagen-Poiseuille equation and Murray's law. Here the conduit structure is modelled as conical pipes and as branching pipes. The force required to lift sap is generated mostly by…

  9. Face-Lift

    Science.gov (United States)

    Tests and Procedures Face-lift By Mayo Clinic Staff A face-lift (rhytidectomy) is a cosmetic surgical procedure to improve the look of your face and neck. During a face-lift, facial soft tissues are lifted, excess skin is ...

  10. Keeping HL-LHC accountable

    CERN Multimedia

    2015-01-01

    This week saw the cost and schedule of the High Luminosity LHC (HL-LHC) and LHC Injectors Upgrade (LIU) projects come under close scrutiny from the external review committee set up for the purpose.    HL-LHC, whose implementation requires an upgrade to the CERN injector complex, responds directly to one of the key recommendations of the updated European Strategy for Particle Physics, which urges CERN to prepare for a ‘major luminosity upgrade’, a recommendation that is also perfectly in line with the P5 report on the US strategy for the field. Responding to this recommendation, CERN set up the HL-LHC project in 2013, partially supported by FP7 funding through the HiLumi LHC Design Study (2011-2015), and coordinated with the American LARP project, which oversees the US contribution to the upgrade. A key element of HL-LHC planning is a mechanism for receiving independent expert advice on all aspects of the project.  To this end, several technical reviews h...

  11. Lift truck safety review

    Energy Technology Data Exchange (ETDEWEB)

    Cadwallader, L.C.

    1997-03-01

    This report presents safety information about powered industrial trucks. The basic lift truck, the counterbalanced sit down rider truck, is the primary focus of the report. Lift truck engineering is briefly described, then a hazard analysis is performed on the lift truck. Case histories and accident statistics are also given. Rules and regulations about lift trucks, such as the US Occupational Safety an Health Administration laws and the Underwriter`s Laboratories standards, are discussed. Safety issues with lift trucks are reviewed, and lift truck safety and reliability are discussed. Some quantitative reliability values are given.

  12. Forehead lift - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100020.htm Forehead lift - series—Indications To use the sharing features on ... to slide 3 out of 3 Overview Forehead lifts are most commonly done for people in their ...

  13. Breast lift (mastopexy) - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100188.htm Breast lift (mastopexy) - series—Incisions To use the sharing features ... to slide 3 out of 3 Overview Breast lift (mastopexy) is usually performed for drooping breasts, which ...

  14. Inexpensive Dramatic Pneumatic Lift

    Science.gov (United States)

    Morse, Robert A.

    2017-09-01

    Various experiments and demonstrations relate air pressure and air pressure difference to force and area. Carpenter and Minnix describe a large-scale pneumatic lift in which a person sitting on a board atop a plastic garbage bag is lifted when the bag is connected to the exhaustport of a vacuum cleaner, which easily lifts the person. This article describes the construction and use of an inexpensive hand-held pneumatic lift to demonstrate the same principle.

  15. Inexpensive Dramatic Pneumatic Lift

    Science.gov (United States)

    Morse, Robert A.

    Various experiments and demonstrations relate air pressure and air pressure difference to force and area. Carpenter and Minnix describe a large-scale pneumatic lift in which a person sitting on a board atop a plastic garbage bag is lifted when the bag is connected to the exhaustport of a vacuum cleaner, which easily lifts the person. This article…

  16. Breast Lift (Mastopexy)

    Science.gov (United States)

    Tests and Procedures Breast lift By Mayo Clinic Staff A breast lift — also known as mastopexy — is a surgical procedure to change the shape of your breasts. During a breast lift, excess skin is removed and breast tissue is ...

  17. HYDRAULIC SERVO

    Science.gov (United States)

    Wiegand, D.E.

    1962-05-01

    A hydraulic servo is designed in which a small pressure difference produced at two orifices by an electrically operated flapper arm in a constantly flowing hydraulic loop is hydraulically amplified by two constant flow pumps, two additional orifices, and three unconnected ball pistons. Two of the pistons are of one size and operate against the additional orifices, and the third piston is of a different size and operates between and against the first two pistons. (AEC)

  18. Lifting endomorphisms to automorphisms

    OpenAIRE

    Arveson, William; Courtney, Dennis

    2007-01-01

    Normal endomorphisms of von Neumann algebras need not be extendable to automorphisms of a larger von Neumann algebra, but they always have asymptotic lifts. We describe the structure of endomorphisms and their asymptotic lifts in some detail, and apply those results to complete the identification of asymptotic lifts of unital completely positive linear maps on von Neumann algebras in terms of their minimal dilations to endomorphisms.

  19. Arm Lifting Circuit and Features of Large Face-shovel Hydraulic Excavator%大型正铲液压挖掘机斗杆升降回路及特性

    Institute of Scientific and Technical Information of China (English)

    王永进; 权龙; 杨敬

    2014-01-01

    在设计目前国内斗容和机重最大的矿用液压挖掘机液压控制系统中,为减小使用成本,采用交流电动机驱动变量液压泵组作为动力源。为满足工作效率要求,斗杆举升过程采用四台液压泵供油,通过四组比例多路阀(主控阀)阀外合流来满足斗杆的速度要求,为降低能耗,提出在斗杆下降过程依靠自重和专用的比例节流阀进行流量再生的控制方法,加快斗杆下降速度,提高系统工作效率。分析斗杆采用流量再生方法下降的前提条件,对斗杆液压缸在一个工作循环内的压力变化进行机电液一体化的联合仿真研究,按照仿真确定的参数设计并制造样机,试验测试表明,挖掘机加载最大试验负载25 kN时,所设计的液压控制系统可以满足斗杆满载举升所需要的压力及速度要求,斗杆下降采用流量再生方法后,下降时间由32 s缩短至18 s,下降速度明显加快,且下降结束阶段无液压冲击。通过试验,验证了挖掘机液压控制方案的正确性,为今后国内设计和制造更大型的液压挖掘机积累了数据和经验。%During the course of designing the hydraulic control system of hydraulic excavators with the domestic largest bucket capacity and machine weight, electricity with AC motor driving hydraulic pumps is used as a power source to reduce the cost. To meet the efficiency requirements, four oil pumps are adopted while the arm is uplifting. Incorporation outside the valve through four groups of proportional multi-way valve(master valve) is carried out to meet speed requirements. In order to reduce energy consumption, the control method of flow regeneration is put forward which depends on the arm’s own weight and dedicated proportional throttle valve while the arm is declining to accelerate its declining speed and improve the efficiency of the system. In the article the prerequisite for the arm declining is

  20. 大型水压机阀芯驱动系统凸轮升程曲线设计%Design of cam lifting profiles used to drive spool system in large hydraulic press

    Institute of Scientific and Technical Information of China (English)

    陈玲; 谭建平; 杨俊; 陈晖

    2013-01-01

    针对大型水压机阀芯驱动系统中凸轮顶杆机构所受侧向力巨大和瞬变的特点,提出一种适合于该特点的凸轮轮廓曲线设计方法,该方法通过寻找最优的圆弧曲线轮廓使凸轮的压力角在阀芯开启力最大时具有较小的值.将该方法应用于300 MN模锻水压机阀芯驱动系统的凸轮设计,通过建立阀芯驱动系统的模型,对比了最优圆弧凸轮和直线轮廓凸轮对系统动态特性的影响,结果表明:最优圆弧凸轮阀芯驱动系统的液压缸驱动降低了22%,阀芯开启力下降了5 kN,开启的速度更加平稳,设备运行更加稳定,使用寿命得到了极大的提高.%Considering the huge and transient lateral force that the cam followers institutions suffered in the spool drive system of large hydraulic press, a new cam profile curve design method was presented. This method tries to find the optimal arc curved contour to ensure a smaller value of the pressure angle of cam when the opening force of the spool is the maximum. The method was applied in the cam design of the spool drive system in 300 MN forging hydraulic press. The effects on system dynamics of the optimal arc cam and straight line contour cam were compared through the establishment of the spool drive system model. The results show that the drives of hydraulic cylinder in the spool driving system with the optimal arc cam can be reduced by 22% , the opening force declines 5 kN, the opening speed is smoother, the operation state is more stable, and the service life of the equipment is greatly prolonged.

  1. Basic hydraulics

    CERN Document Server

    Smith, P D

    1982-01-01

    BASIC Hydraulics aims to help students both to become proficient in the BASIC programming language by actually using the language in an important field of engineering and to use computing as a means of mastering the subject of hydraulics. The book begins with a summary of the technique of computing in BASIC together with comments and listing of the main commands and statements. Subsequent chapters introduce the fundamental concepts and appropriate governing equations. Topics covered include principles of fluid mechanics; flow in pipes, pipe networks and open channels; hydraulic machinery;

  2. Understanding Wing Lift

    Science.gov (United States)

    Silva, J.; Soares, A. A.

    2010-01-01

    The conventional explanation of aerodynamic lift based on Bernoulli's equation is one of the most common mistakes in presentations to school students and is found in children's science books. The fallacies in this explanation together with an alternative explanation for aerofoil lift have already been presented in an excellent article by Babinsky…

  3. Hydraulic Structures

    Data.gov (United States)

    Department of Homeland Security — This table is required whenever hydraulic structures are shown in the flood profile. It is also required if levees are shown on the FIRM, channels containing the...

  4. Dubai gas lift automation

    Energy Technology Data Exchange (ETDEWEB)

    Coltharp, E.D.; Khokhar, M.

    1984-09-01

    Dubai Petroleum Company has recently installed a computer gas lift surveillance and gas lift gas injection control system in the Fateh and S.W. Fateh Fields located in the southern part of the Arabian Gulf. This system is the fourth generation of the computer control system installed in California in 1971 by Conoco, Inc. This paper describes the advantages and problems in this system to monitor and control the gas lift operation of 116 wells through 30 intelligent remote terminal units (RTU). In addition, this system monitors the condition of critical operational

  5. FREIGHT CONTAINER LIFTING STANDARD

    Energy Technology Data Exchange (ETDEWEB)

    POWERS DJ; SCOTT MA; MACKEY TC

    2010-01-13

    This standard details the correct methods of lifting and handling Series 1 freight containers following ISO-3874 and ISO-1496. The changes within RPP-40736 will allow better reading comprehension, as well as correcting editorial errors.

  6. Wind tower service lift

    Science.gov (United States)

    Oliphant, David; Quilter, Jared; Andersen, Todd; Conroy, Thomas

    2011-09-13

    An apparatus used for maintaining a wind tower structure wherein the wind tower structure may have a plurality of legs and may be configured to support a wind turbine above the ground in a better position to interface with winds. The lift structure may be configured for carrying objects and have a guide system and drive system for mechanically communicating with a primary cable, rail or other first elongate member attached to the wind tower structure. The drive system and guide system may transmit forces that move the lift relative to the cable and thereby relative to the wind tower structure. A control interface may be included for controlling the amount and direction of the power into the guide system and drive system thereby causing the guide system and drive system to move the lift relative to said first elongate member such that said lift moves relative to said wind tower structure.

  7. Six-degree-of-freedom guidance and control-entry analysis of the HL-20

    Science.gov (United States)

    Powell, Richard W.

    1993-10-01

    The ability of the HL-20 lifting body to fly has been evaluated for an automated entry from atmospheric interface to landing. This evaluation was required to demonstrate that not only successful touchdown conditions would be possible for this low lift-to-drag-ratio vehicle, but also the vehicle would not exceed its design dynamic pressure limit of 400 psf during entry. This dynamic pressure constraint limit, coupled with limited available pitch-control authority at low supersonic speeds, restricts the available maneuvering capability for the HL-20 to acquire the runway. One result of this analysis was that this restrictive maneuvering capability does not allow the use of a model-following atmospheric entry-guidance algorithm, such as that used by the Space Shuttle, but instead requires a more adaptable guidance algorithm. Therefore, for this analysis, a predictor-corrector guidance algorithm was developed that would provide successful touchdown conditions while not violating the dynamic pressure constraint. A flight-control system was designed and incorporated, along with the predictor-corrector guidance algorithm, into a six-DOF simulation. which showed that the HL-20 remained controllable and could reach the landing site and execute a successful landing under all off-nominal conditions simulated.

  8. Refined AFC-Enabled High-Lift System Integration Study

    Science.gov (United States)

    Hartwich, Peter M.; Shmilovich, Arvin; Lacy, Douglas S.; Dickey, Eric D.; Scalafani, Anthony J.; Sundaram, P.; Yadlin, Yoram

    2016-01-01

    A prior trade study established the effectiveness of using Active Flow Control (AFC) for reducing the mechanical complexities associated with a modern high-lift system without sacrificing aerodynamic performance at low-speed flight conditions representative of takeoff and landing. The current technical report expands on this prior work in two ways: (1) a refined conventional high-lift system based on the NASA Common Research Model (CRM) is presented that is more representative of modern commercial transport aircraft in terms of stall characteristics and maximum Lift/Drag (L/D) ratios at takeoff and landing-approach flight conditions; and (2) the design trade space for AFC-enabled high-lift systems is expanded to explore a wider range of options for improving their efficiency. The refined conventional high-lift CRM (HL-CRM) concept features leading edge slats and slotted trailing edge flaps with Fowler motion. For the current AFC-enhanced high lift system trade study, the refined conventional high-lift system is simplified by substituting simply-hinged trailing edge flaps for the slotted single-element flaps with Fowler motion. The high-lift performance of these two high-lift CRM variants is established using Computational Fluid Dynamics (CFD) solutions to the Reynolds-Averaged Navier-Stokes (RANS) equations. These CFD assessments identify the high-lift performance that needs to be recovered through AFC to have the CRM variant with the lighter and mechanically simpler high-lift system match the performance of the conventional high-lift system. In parallel to the conventional high-lift concept development, parametric studies using CFD guided the development of an effective and efficient AFC-enabled simplified high-lift system. This included parametric trailing edge flap geometry studies addressing the effects of flap chord length and flap deflection. As for the AFC implementation, scaling effects (i.e., wind-tunnel versus full-scale flight conditions) are addressed

  9. The winds from HL Tau

    Science.gov (United States)

    Klaassen, P. D.; Mottram, J. C.; Maud, L. T.; Juhasz, A.

    2016-01-01

    Outflowing motions, whether a wind launched from the disc, a jet launched from the protostar, or the entrained molecular outflow, appear to be a ubiquitous feature of star formation. These outwards motions have a number of root causes, and how they manifest is intricately linked to their environment as well as the process of star formation itself. Using the Atacama Large Millimeter/submillimeter Array (ALMA) Science Verification data of HL Tau, we investigate the high-velocity molecular gas being removed from the system as a result of the star formation process. We aim to place these motions in context with the optically detected jet, and the disc. With these high-resolution (∼1 arcsec) ALMA observations of CO (J=1−0), we quantify the outwards motions of the molecular gas. We find evidence for a bipolar outwards flow, with an opening angle, as measured in the redshifted lobe, starting off at 90°, and narrowing to 60° further from the disc, likely because of magnetic collimation. Its outwards velocity, corrected for inclination angle is of the order of 2.4 km s−1. PMID:27559304

  10. The Winds from HL Tau

    CERN Document Server

    Klaassen, Pamela D; Maud, Luke T; Juhasz, Attila

    2016-01-01

    Outflowing motions, whether a wind launched from the disk, a jet launched from the protostar, or the entrained molecular outflow, appear to be an ubiquitous feature of star formation. These outwards motions have a number of root causes, and how they manifest is intricately linked to their environment as well as the process of star formation itself. Using the ALMA Science Verification data of HL Tau, we investigate the high velocity molecular gas being removed from the system as a result of the star formation process. We aim to place these motions in context with the optically detected jet, and the disk. With these high resolution ($\\sim 1"$) ALMA observations of CO (J=1-0), we quantify the outwards motions of the molecular gas. We find evidence for a bipolar outwards flow, with an opening angle, as measured in the red-shifted lobe, starting off at 90$^\\circ$, and narrowing to 60$^\\circ$ further from the disk, likely because of magnetic collimation. Its outwards velocity, corrected for inclination angle is of ...

  11. The HL-LHC accelerator physics challenges

    CERN Document Server

    Fartoukh, S

    2014-01-01

    We review the conceptual baseline of the HL-LHC project, putting into perspective the main beam physics challenges of this new collider in comparison with the existing LHC, and the series of solutions and possible mitigation measures presently envisaged.

  12. High Lift Common Research Model for Wind Tunnel Testing: An Active Flow Control Perspective

    Science.gov (United States)

    Lin, John C.; Melton, Latunia P.; Viken, Sally A.; Andino, Marlyn Y.; Koklu, Mehti; Hannon, Judith A.; Vatsa, Veer N.

    2017-01-01

    This paper provides an overview of a research and development effort sponsored by the NASA Advanced Air Transport Technology Project to achieve the required high-lift performance using active flow control (AFC) on simple hinged flaps while reducing the cruise drag associated with the external mechanisms on slotted flaps of a generic modern transport aircraft. The removal of the external fairings for the Fowler flap mechanism could help to reduce drag by 3.3 counts. The main challenge is to develop an AFC system that can provide the necessary lift recovery on a simple hinged flap high-lift system while using the limited pneumatic power available on the aircraft. Innovative low-power AFC concepts will be investigated in the flap shoulder region. The AFC concepts being explored include steady blowing and unsteady blowing operating in the spatial and/or temporal domain. Both conventional and AFC-enabled high-lift configurations were designed for the current effort. The high-lift configurations share the cruise geometry that is based on the NASA Common Research Model, and therefore, are also open geometries. A 10%-scale High Lift Common Research Model (HL-CRM) is being designed for testing at the NASA Langley Research Center 14- by 22-Foot Subsonic Tunnel during fiscal year 2018. The overall project plan, status, HL-CRM configurations, and AFC objectives for the wind tunnel test are described.

  13. Regional changes in spine posture at lift onset with changes in lift distance and lift style.

    Science.gov (United States)

    Gill, K Peter; Bennett, Simon J; Savelsbergh, Geert J P; van Dieën, Jaap H

    2007-07-01

    Repeated measures experiment. To determine the effect of changes in horizontal lift distance on the amount of flexion, at lift onset, in different spine regions when using different lift styles. By approximating spine bending during lifting as a pure rotation about a single revolute joint, the differential effects of task constraints and instructions on motions of different spine levels will be obscured. Eight participants lifted a 10-kg crate from the floor, 10 times at each of five distances. Participants were instructed to use freestyle (a participant's preferred lift style), squat, or stoop lift styles. Kinematic data were collected from the mid thoracic spine, lower thoracic/upper lumbar spine, mid lumbar spine, and the lower lumbar spine at lift onset. A whole spine angle was also calculated. Flexion of the lower lumbar spine was not affected by lift distance and style. Differences between lift styles occurred mainly in the mid thoracic and the lower thoracic/upper lumbar regions. With increasing horizontal distance, changes in lift style occurred in the upper three spine regions. These results suggest that the tensile strain on tissues in the lower lumbar spine, which can be a cause of injury in lifting, was not affected by lift style or horizontal lift distance when lifting from floor level.

  14. [Endoscopy and face-lift].

    Science.gov (United States)

    Dardour, J C; Abbou, R

    2017-08-02

    For many years, the face-lift has not been the only intervention for facial rejuvenation. It is necessary today to specify the type of face-lift, cervico-facial lifting, frontal lifting or facelift. We will consider in this article the frontal lift and centro-facial lift and its possible execution assisted by endoscopy with therefore minimal scars, hidden in the scalp. We will consider successively its technique, its indications and its results highlighting a very long hold over time. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  15. Associations between Heat-Stable (O) and Heat-Labile (HL) Serogroup Antigens of Campylobacter jejuni: Evidence for Interstrain Relationships within Three O/HL Serovars

    OpenAIRE

    Jackson, C. J.; Fox, A. J.; Jones, D M; Wareing, D. R. A.; Hutchinson, D. N.

    1998-01-01

    A comparative examination of the heat-stable (O) and heat-labile (HL) serogrouping results for 9,024 sporadic human isolates of Campylobacter jejuni revealed conserved associations between specific O and HL antigens (O/HL serovars). Forty-nine percent of the isolates which grouped for both O and HL antigens belonged to one of three serovars: O 4 complex/HL 1 (17.9%), O 1/HL 2 (16.8%), or O 50/HL 7 (14.5%). Other common serovars were O 2/HL 4 (8.3%), O 6/HL 6 (8.1%), O 53/HL 11 (4.5%), O 19/HL...

  16. Arm Lift (Brachioplasty)

    Science.gov (United States)

    ... sagging. An arm lift might also boost your body image. As you get older, the skin on your upper arms changes — sagging and becoming loose. Significant weight loss also can cause the undersides of your upper arms to droop. While exercise can strengthen and improve muscle tone in the ...

  17. Lifting as You Climb

    Science.gov (United States)

    Sullivan, Debra R.

    2009-01-01

    This article addresses leadership themes and answers leadership questions presented to "Exchange" by the Panel members who attended the "Exchange" Panel of 300 Reception in Dallas, Texas, last November. There is an old proverb that encourages people to lift as they climb: "While you climb a mountain, you must not forget others along the way." With…

  18. Heterotic weight lifting

    Energy Technology Data Exchange (ETDEWEB)

    Gato-Rivera, B. [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands); Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain); Schellekens, A.N., E-mail: t58@nikhef.n [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands); Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain); IMAPP, Radboud Universiteit, Nijmegen (Netherlands)

    2010-03-21

    We describe a method for constructing genuinely asymmetric (2,0) heterotic strings out of N=2 minimal models in the fermionic sector, whereas the bosonic sector is only partly build out of N=2 minimal models. This is achieved by replacing one minimal model plus the superfluous E{sub 8} factor by a non-supersymmetric CFT with identical modular properties. This CFT generically lifts the weights in the bosonic sector, giving rise to a spectrum with fewer massless states. We identify more than 30 such lifts, and we expect many more to exist. This yields more than 450 different combinations. Remarkably, despite the lifting of all Ramond states, it is still possible to get chiral spectra. Even more surprisingly, these chiral spectra include examples with a certain number of chiral families of SO(10), SU(5) or other subgroups, including just SU(3)xSU(2)xU(1). The number of families and mirror families is typically smaller than in standard Gepner models. Furthermore, in a large number of different cases, spectra with three chiral families can be obtained. Based on a first scan of about 10% of the lifted Gepner models we can construct, we have collected more than 10,000 distinct spectra with three families, including examples without mirror fermions. We present an example where the GUT group is completely broken to the standard model, but the resulting and inevitable fractionally charged particles are confined by an additional gauge group factor.

  19. On classical and quantum liftings

    CERN Document Server

    Accardi, L; Kossakowski, A; Matsuoka, T; Ohya, M

    2011-01-01

    We analyze the procedure of lifting in classical stochastic and quantum systems. It enables one to `lift' a state of a system into a state of `system+reservoir'. This procedure is important both in quantum information theory and the theory of open systems. We illustrate the general theory of liftings by a particular class related to so called circulant states.

  20. Helicopter Toy and Lift Estimation

    Science.gov (United States)

    Shakerin, Said

    2013-01-01

    A $1 plastic helicopter toy (called a Wacky Whirler) can be used to demonstrate lift. Students can make basic measurements of the toy, use reasonable assumptions and, with the lift formula, estimate the lift, and verify that it is sufficient to overcome the toy's weight. (Contains 1 figure.)

  1. Helicopter Toy and Lift Estimation

    Science.gov (United States)

    Shakerin, Said

    2013-01-01

    A $1 plastic helicopter toy (called a Wacky Whirler) can be used to demonstrate lift. Students can make basic measurements of the toy, use reasonable assumptions and, with the lift formula, estimate the lift, and verify that it is sufficient to overcome the toy's weight. (Contains 1 figure.)

  2. The Hydraulic Ram (Or Impulse) Pump

    Science.gov (United States)

    Mills, Allan

    2014-01-01

    The hydraulic impulse pump utilizes a fraction of the momentum of a flowing stream to lift a small portion of that water to a higher level. There it may be accumulated in an elevated cistern to provide sufficient water for several families, for the pump works 24 h a day with no additional source of energy. The operation of the pump is described,…

  3. Lift performance and lumbar loading in standing and seated lifts.

    Science.gov (United States)

    Middleton, Kane J; Carstairs, Greg L; Ham, Daniel J

    2016-09-01

    This study investigated the effect of posture on lifting performance. Twenty-three male soldiers lifted a loaded box onto a platform in standing and seated postures to determine their maximum lift capacity and maximum acceptable lift. Lift performance, trunk kinematics, lumbar loads, anthropometric and strength data were recorded. There was a significant main effect for lift effort but not for posture or the interaction. Effect sizes showed that lumbar compression forces did not differ between postures at lift initiation (Standing 5566.2 ± 627.8 N; Seated 5584.0 ± 16.0) but were higher in the standing posture (4045.7 ± 408.3 N) when compared with the seated posture (3655.8 ± 225.7 N) at lift completion. Anterior shear forces were higher in the standing posture at both lift initiation (Standing 519.4 ± 104.4 N; Seated 224.2 ± 9.4 N) and completion (Standing 183.3 ± 62.5 N; Seated 71.0 ± 24.2 N) and may have been a result of increased trunk flexion and a larger horizontal distance of the mass from the L5-S1 joint. Practitioner Summary: Differences between lift performance and lumbar forces in standing and seated lifts are unclear. Using a with-in subjects repeated measures design, we found no difference in lifted mass or lumbar compression force at lift initiation between standing and seated lifts.

  4. Transformable Heavy Lift Ship

    Science.gov (United States)

    2007-08-01

    the 500 group include climate control, freshwater/seawater systems, mechanical handling, and special purpose systems. Due to the large troop...compliment carried on the JHSS, large amounts of climate control and ventilation were required. The transformable heavy lift ship has only a single... Treeline Connector Innovation Cell Naval Research Enterprise Intern Program Final Report, NSWCCD-20-TR-2005/05 August 2005 "Saturn." Nijhuis

  5. Heterotic Weight Lifting

    CERN Document Server

    Gato-Rivera, B

    2009-01-01

    We describe a method for constructing genuinely asymmetric (2,0) heterotic strings out of N=2 minimal models in the fermionic sector, whereas the bosonic sector is only partly build out of N=2 minimal models. This is achieved by replacing one minimal model plus the superfluous E_8 factor by a non-supersymmetric CFT with identical modular properties. This CFT generically lifts the weights in the bosonic sector, giving rise to a spectrum with fewer massless states. We identify more than 30 such lifts, and we expect many more to exist. This yields more than 450 different combinations. Remarkably, despite the lifting of all Ramond states, it is still possible to get chiral spectra. Even more surprisingly, these chiral spectra include examples with a certain number of chiral families of SO(10), SU(5) or other subgroups, including just SU(3) x SU(2) x U(1). The number of families and mirror families is typically smaller than in standard Gepner models. Furthermore, in a large number of different cases, spectra with ...

  6. Analysis of multicriteria models application for selection of an optimal artificial lift method in oil production

    OpenAIRE

    Crnogorac, Miroslav P.; Danilović, Dušan Š.; Karović-Maričić, Vesna D.; Leković, Branko A.

    2016-01-01

    In the world today for the exploitation of oil reservoirs by artificial lift methods are applied different types of deep pumps (piston, centrifugal, screw, hydraulic), water jet pumps and gas lift (continuous, intermittent and plunger). Maximum values of oil production achieved by these exploitation methods are significantly different. In order to select the optimal exploitation method of oil well, the multicriteria analysis models are used. In this paper is presented an analysis of the multi...

  7. HL7 Messaging Engine with Customizable Translation System

    Directory of Open Access Journals (Sweden)

    PRODAN, R.

    2010-05-01

    Full Text Available This paper introduces a new client-server messaging engine used to exchange clinical data between various medical software applications. Our portal uses the HL7 (Health Level Seven messaging standard to provide translated clinical data to HL7 and non-HL7 client applications. We used HL7 because this standard is worldwide used to facilitate the communication between clinical applications.

  8. [Preparation of cytoplasts from HL-60 cells].

    Science.gov (United States)

    Wang, Lili; Yu, Huangfei; Fang, Ning; Chen, Daixiong

    2013-06-01

    This experimental research was aimed to establish an optimum system of enucleation, purification and identification for preparing the cytoplasts of suspension culture cells in order to undertake cell recombination. Human leukemia HL-60 cells in suspension culture were purified by 42% Percoll density gradient centrifugation and low-speed centrifugation at 1 500r/min, respectively. The purified HL-60 cells were treated with cytochalasin B (CB) alone or combined with colcchicine and enucleated by isopycnic gradient centrifugation on 50% Percoll at 25 degrees C and 34 degrees C, respectively. Cytoplasts made from HL-60 cells were purified through gradient centrifugation by 37%, 38% and 40% Percoll, respectively. The final cytoplasts were identified by Wright-Giemsa staining and 4,6-diamidino-2-phenylidole dihydrochloride (DAPI)/5, 6-carboxyflu-orescein diacetate succinimidyl ester (CFSE) double-staining. The phenotype and mitochondrial membrane potential of HL-60 cytoplasts were analyzed by flow cytometry. The results indicated that the enucleation ratio of HL-60 cells induced by CB combined with colcchicine was up to 91. 98% +/-4. 29%, which was significantly higher than that in CB alone group (74. 95% +/- 3. 02%)(PHL-60 cytoplasts had no significant change, and the activity of the cytoplasts was above 80% within 12h. It is concluded that enucleation throuth density gradient centrifugation on 50% Percoll mediated by CB combined with colcchicine, 38%Percoll of purification followed by DAPI/CFSE double labeling and MMP detection is an optimum scheme for preparation and identification of cytoplast from suspension culture cells.

  9. Rannarootslaste suurmees Hans Pöhl / Olev Liivik

    Index Scriptorium Estoniae

    Liivik, Olev, 1975-

    2011-01-01

    Arvustus: Estlandssvenskarnas hövding. En biografi över Hans Pöhl (1876-1930), estlandssvenskarnas främste företrädare och ledare = Hans Pöhl - rannarootslaste eestvõileja : Hans Pöhl (1876-1930), Eesti rootslaste vaimse liidri ja valgustaja elulugu. Stockholm, 2010

  10. Lifting speed preferences and their effects on the maximal lifting capacity.

    Science.gov (United States)

    Lin, Chiuhsiang Joe; Cheng, Chih-Feng

    2017-02-07

    The objectives of this study were to evaluate how lifting capacity and subjective preferences are affected by different lifting speeds. The maximum lifting capacity of lift was determined with three independent variables, lifting speed, lifting technique, and lifting height. Questionnaires were evaluated after the experiment by the participants for the lifting speed preferences. This study found that the lifting speed was a significant factor in the lifting capacity (plifting height (plifting speed and lifting height (p=0.005) affected the lifting capacity significantly. The maximal lifting capacity was achieved around the optimal speed that was neither too fast nor too slow. Moreover, the participants' preferred lifting speeds were consistently close to the optimal lifting speed. The results showed that the common lifting practice guideline to lift slowly might make the worker unable to generate a large lifting capacity.

  11. Hydraulic Evaluation of Marmet Lock Filling and Emptying System, Kanawha River, West Virginia

    Science.gov (United States)

    2015-04-01

    Army Engineer Waterways Experiment Station. Headquarters, U.S. Army Corps of Engineers. 1975. Hydraulic design of lock culvert valves . Engineer Manual ...operations with various valve operations was computed. The numerical model results indicate that the hydraulic conditions are not significantly...2 1.3 Vertical-Lift Valves

  12. Hans Pöhl - Estlandssvenskarnas hövding = Hans Pöhl - rannarootslaste eestvõitleja / Torkel Jansson

    Index Scriptorium Estoniae

    Jansson, Torkel, 1947-

    2011-01-01

    Raamatututvustus: Hans Pöhl - Estlandssvenskarnas hövding : en biografi över Hans Pöhl (1876-1930), estlandssvenskarnas främste företrädare och ledare = Hans Pöhl - rannarootslaste eestvõitleja : Hans Pöhli (1876-1930), Eesti rootslaste vaimse liidri ja valgustaja elulugu. (Stockholm ; Tallinn, 2010)

  13. In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl-/-) mice.

    Science.gov (United States)

    Chen, Jeffrey; Kaiyala, Karl J; Lam, Jennifer; Agrawal, Nalini; Nguyen, Lisa; Ogimoto, Kayoko; Spencer, Dean; Morton, Gregory J; Schwartz, Michael W; Dichek, Helén L

    2015-04-01

    The lean body weight phenotype of hepatic lipase (HL)-deficient mice (hl(-/-)) suggests that HL is required for normal weight gain, but the underlying mechanisms are unknown. HL plays a unique role in lipoprotein metabolism performing bridging as well as catalytic functions, either of which could participate in energy homeostasis. To determine if both the catalytic and bridging functions or the catalytic function alone are required for the effect of HL on body weight, we studied (hl(-/-)) mice that transgenically express physiologic levels of human (h)HL (with catalytic and bridging functions) or a catalytically-inactive (ci)HL variant (with bridging function only) in which the catalytic Serine 145 was mutated to Alanine. As expected, HL activity in postheparin plasma was restored to physiologic levels only in hHL-transgenic mice (hl(-/-)hHL). During high-fat diet feeding, hHL-transgenic mice exhibited increased body weight gain and body adiposity relative to hl(-/-)ciHL mice. A similar, albeit less robust effect was observed in female hHL-transgenic relative to hl(-/-)ciHL mice. To delineate the basis for this effect, we determined cumulative food intake and measured energy expenditure using calorimetry. Interestingly, in both genders, food intake was 5-10% higher in hl(-/-)hHL mice relative to hl(-/-)ciHL controls. Similarly, energy expenditure was ~10% lower in HL-transgenic mice after adjusting for differences in total body weight. Our results demonstrate that (1) the catalytic function of HL is required to rescue the lean body weight phenotype of hl(-/-) mice; (2) this effect involves complementary changes in both sides of the energy balance equation; and (3) the bridging function alone is insufficient to rescue the lean phenotype of hl(-/-)ciHL mice.

  14. Knees Lifted High

    Centers for Disease Control (CDC) Podcasts

    2008-08-04

    The Eagle Books are a series of four books that are brought to life by wise animal characters - Mr. Eagle, Miss Rabbit, and Coyote - who engage Rain That Dances and his young friends in the joy of physical activity, eating healthy foods, and learning from their elders about health and diabetes prevention. Knees Lifted High gives children fun ideas for active outdoor play.  Created: 8/4/2008 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2008.

  15. Lift application development cookbook

    CERN Document Server

    Garcia, Gilberto T

    2013-01-01

    Lift Application Development Cookbook contains practical recipes on everything you will need to create secure web applications using this amazing framework.The book first teaches you basic topics such as starting a new application and gradually moves on to teach you advanced topics to achieve a certain task. Then, it explains every step in detail so that you can build your knowledge about how things work.This book is for developers who have at least some basic knowledge about Scala and who are looking for a functional, secure, and modern web framework. Prior experience with HTML and JavaScript

  16. Vacuum System for HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    曹曾; 崔成和; 刘德权; 蔡萧; 高霄燕

    2005-01-01

    The vacuum system for HL-2A was built in 2003. The test results indicated that this system is feasible. It consists of three main parts: a pumping system, a pumping divertor and a glow discharge cleaning (GDC) system. For the pumping system, there are three main functions:(1) evacuating the vacuum vessel thus to produce an ultra high vacuum, (2) removal of impurities released during baking and (3) pumping during GDC. The pumping divertor controls the particles at the plasma edge and the GDC system provides a clean wall conditioning. During the first campaign of physical trial experiment on HL-2A, the ultimate pressure reached 4.6×10-6 Pa, and of ASDEX.

  17. ATLAS Upgrade for the HL-LHC

    CERN Document Server

    Oakham, F G; The ATLAS collaboration

    2012-01-01

    With the LHC successfully collecting data at 7 TeV, plans are actively advancing for a series of upgrades leading eventually to about five times the LHC design-luminosity some 10 years from now in the high luminosity LHC (HL-LHC) project. The goal is to extend the data set from about 300 fb-1 proposed for LHC running to 3000 fb-1 by around 2030. Coping with the high instantaneous and integrated luminosity will require many changes to the ATLAS detector. The designs are developing rapidly for an all-new inner-tracker, big changes in the calorimeter and muon systems, as well as improved triggers. This talk summarises the environment expected at the HL-LHC and the status of various improvements to the ATLAS detector.

  18. HL-2A Shot Program Editor

    Institute of Scientific and Technical Information of China (English)

    SONGXianming; JIANGChao; LIFeidi; LIQiang; FANMingjie; CHENLiaoyuan; LUOCuiwen; WANGMinghong; TANGFangqiong; LIULi; MAOSuying

    2001-01-01

    A tokamak plasma discharge involves a series of complex and concerted actions conducted by its control system. The HL-2A control system can be divided into two partst, the machine control system and the discharge control system. The machine control system, which consists of industrial PC (IPC), configures and operates the tokamak' s various technical subsystems. Timing sys-tem is integrated into machine control system giving absolute time for all subsystems. The discharge control system,

  19. A Spectroscopic Study of HL Canis Majoris

    OpenAIRE

    Sheets, H. A.; Thorstensen, John R.

    2005-01-01

    We present optical spectroscopy of the dwarf nova HL Canis Majoris over a span of four years. The observations were made during standstill, outburst, and quiescence. We determine an orbital period of 0.2167867 +/- 0.0000017 days, based on radial velocities determined from H-alpha, H-beta, and He I 5876 emission. We also present equivalent widths of the spectral features in outburst and in quiescence.

  20. HL-LHC updates in Japan

    CERN Document Server

    Antonella Del Rosso

    2014-01-01

    At a recent meeting in Japan, updates on the High Luminosity LHC (HL-LHC) project were presented, including the progress made so far and the deadlines still to be met for the upgraded machine to be operational from 2020.   New magnets made with advanced superconductor Nb3Sn in the framework of the HL-LHC project. These magnets are currently under construction at CERN by the TE-MSC group. The LHC is the world’s most powerful particle accelerator, and in 2015 it will reach yet another new record for the energy of its colliding beams. One key factor of its discovery potential is its ability to produce collisions described in mathematical terms by the parameter known as “luminosity”. In 2025, the HL-LHC project will allow the total number of collisions in the LHC to increase by a factor of 10. The first step in this rich upgrade programme is the delivery of the Preliminary Design Report (PDR), which is also a key milestone of the HiLumi LHC Design Study partly fund...

  1. Microarray analysis of responsible genes in increased growth rate in the subline of HL60 (HL60RG) cells.

    Science.gov (United States)

    Luan, Yang; Kogi, Mieko; Rajaguru, Palanisamy; Ren, Jin; Yamaguchi, Teruhide; Suzuki, Kazuhiro; Suzuki, Takayoshi

    2012-03-01

    HL60RG, a subline of human promyelocytic leukemia HL60 cells, has a increased growth rate than their parental cells. To gain information of the mechanisms involved in the increased growth rate of HL60RG, we performed a multiplex fluorescence in situ hybridization (M-FISH), standard cytogenetics analysis (G-banding) and genome scan using 10K SNP mapping array on both cell types. Characteristic genomic alterations in HL60RG cells were identified including uniparental disomy (UPD) of chromosome 1, and hemizygous deletion in 10p and 11p. However, no such defects were observed in HL60 cells. Changes in gene expression in HL60RG cells were determined using expression arrays (Affymetrix GeneChip, HU133A). Candidate genes associated with the rapid growth of HL60RG cells were identified. Two tumor necrosis factor receptors, TNFRSF1B (type II tumor necrosis factor-α receptor) and TNFRSF8 (also known as a tumor marker CD30), which are adjacently located on chromosome 1 showed opposing changes in gene expression in HL60RG cells-over-expression of TNFRSF8 and repression of TNFRSF1B. Differences in the DNA methylation status in the transcriptional regulatory regions of both genes between HL60 and HL60RG was detected by a methylation-specific PCR assay. In conclusion, alterations in chromosome and gene expression in HL60RG may be associated with increased growth rate.

  2. Optimal control theory determination of feasible return-to-launch-site aborts for the HL-20 Personnel Launch System vehicle

    Science.gov (United States)

    Dutton, Kevin E.

    1994-01-01

    The personnel launch system (PLS) being studied by NASA is a system to complement the space shuttle and provide alternative access to space. The PLS consists of a manned spacecraft launched by an expendable launch vehicle (ELV). A candidate for the manned spacecraft is the HL-20 lifting body. In the event of an ELV malfunction during the initial portion of the ascent trajectory, the HL-20 will separate from the rocket and perform an unpowered return to launch site (RTLS) abort. This work details an investigation, using optimal control theory, of the RTLS abort scenario. The objective of the optimization was to maximize final altitude. With final altitude as the cost function, the feasibility of an RTLS abort at different times during the ascent was determined. The method of differential inclusions was used to determine the optimal state trajectories, and the optimal controls were then calculated from the optimal states and state rates.

  3. by Lifting Line Method

    Directory of Open Access Journals (Sweden)

    Horia Dumitrescu

    1998-01-01

    Full Text Available The vortex model of propellers is modified and applied to the high-speed horizontal axis turbines. The turbine blades are replaced by lifting lines and trailing vortices which shed along the blade span. The model is not a free wake model, but it is still a nonlinear one which should be solved iteratively. In addition to the regular case where the trailing vortices are constrained to distribute along a helical surface, another version, where each trailing vortex sheding from the blade grows as a free helical vortex line, is also included. Performance parameters are calculated by application of the Biot-Savart law along with the Kutta-Joukowski theorem. Predictions are, shown to compare favorably with existing numerical data from more involved free wake methods, but require less computational effort. Thereby, the present method may be a very useful tool for calculating the aerodynamic loads on horizontal-axis wind turbine blades.

  4. What is a safe lift?

    Science.gov (United States)

    Espinoza, Kathy

    2013-09-01

    In a perfect world, a "safe" lift would be 51 pounds if the object is within 7 inches from the front of the body, if it is at waist height, if it is directly in front of the person, if there is a handle on the object, and if the load inside the box/bucket doesn't shift once lifted. If the load to be lifted does not meet all of these criteria, then it is an unsafe lift, and modifications must be made. Modifications would include lightening the load, getting help, or using a mechanical lifting device. There is always a way to turn an unsafe lift into a safer lift. An excellent resource for anyone interested in eliminating some of the hazards associated with lifting is the "Easy Ergonomics" publication from Cal/OSHA. This booklet offers practical advice on how to improve the workplace using engineering and administrative controls, problem-solving strategies and solutions, and a vast amount of ergonomics information and resources. "Easy Ergonomics" can be obtained by calling Cal/OSHA's education and training unit in Sacramento at 800-963-9424. A free copy can be obtained via www.dir.ca.gov/dosh/puborder.asp.

  5. Project LIFT: Year Two Report

    Science.gov (United States)

    Norton, Michael; Piccinino, Kelly

    2014-01-01

    Research for Action (RFA) has completed its second year of a five-year external evaluation of the Project Leadership and Investment for Transformation (LIFT) Initiative in the Charlotte-Mecklenburg School District (CMS). Project LIFT is a public-private partnership between CMS and the local philanthropic and business communities in Charlotte,…

  6. Project LIFT: Year 1 Report

    Science.gov (United States)

    Norton, Michael; Piccinino, Kelly

    2014-01-01

    Research for Action (RFA) is currently in the second year of a five-year external evaluation of the Project Leadership and Investment for Transformation (LIFT) Initiative in the Charlotte-Mecklenburg School District (CMS). Project LIFT is a public-private partnership between CMS and the local philanthropic and business communities in Charlotte,…

  7. Wavelets and the lifting scheme

    DEFF Research Database (Denmark)

    la Cour-Harbo, Anders; Jensen, Arne

    2012-01-01

    The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge of li...... of linear algebra and signal processing will suffice. The lifting based definition is equivalent to the usual filer bank based definition of the DWT. The article does not discuss applications in any detail. The reader is referred to other articles in this collection.......The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge...

  8. Wavelets and the lifting scheme

    DEFF Research Database (Denmark)

    la Cour-Harbo, Anders; Jensen, Arne

    2009-01-01

    The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge of li...... of linear algebra and signal processing will suffice. The lifting based definition is equivalent to the usual filer bank based definition of the DWT. The article does not discuss applications in any detail. The reader is referred to other articles in this collection.......The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge...

  9. Wavelets and the Lifting Scheme

    DEFF Research Database (Denmark)

    la Cour-Harbo, Anders; Jensen, Arne

    The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge of li...... of linear algebra and signal processing will suffice. The lifting based definition is equivalent to the usual filer bank based definition of the DWT. The article does not discuss applications in any detail. The reader is referred to other articles in this collection.......The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge...

  10. Lift Recovery for AFC-Enabled High Lift System

    Science.gov (United States)

    Shmilovich, Arvin; Yadlin, Yoram; Dickey, Eric D.; Gissen, Abraham N.; Whalen, Edward A.

    2017-01-01

    This project is a continuation of the NASA AFC-Enabled Simplified High-Lift System Integration Study contract (NNL10AA05B) performed by Boeing under the Fixed Wing Project. This task is motivated by the simplified high-lift system, which is advantageous due to the simpler mechanical system, reduced actuation power and lower maintenance costs. Additionally, the removal of the flap track fairings associated with conventional high-lift systems renders a more efficient aerodynamic configuration. Potentially, these benefits translate to a approx. 2.25% net reduction in fuel burn for a twin-engine, long-range airplane.

  11. Von Hippel-Lindau disease (vHL)

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Bisgaard, Søs Marie Luise; Harbud, Vibeke;

    2013-01-01

    These clinical guidelines outline the criteria and recommendations for diagnostic and genetic work-up of families suspected of von Hippel-Lindau disease (vHL), as well as recommendations for prophylactic surveillance for vHL patients. The guideline has been composed by the Danish Coordination Group...... for vHL which is comprised of Danish doctors and specialists interested in vHL. The recommendations are based on longstanding clinical experience, Danish original research, and extensive review of the international literature. vHL is a hereditary multi-tumour disease caused by germline mutations...... of the disease, and/or in individuals with a vHL-associated manifestation; i.e. a hemangioblastoma in the retina or the central nervous system, familial or bilateral pheochromocytomas, familial, multiple, or early onset renal cell carcinomas, and in individuals with an endolymphatic sac tumour in the inner ear...

  12. Von Hippel-Lindau disease (vHL)

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Bisgaard, Søs Marie Luise; Harbud, Vibeke

    2013-01-01

    These clinical guidelines outline the criteria and recommendations for diagnostic and genetic work-up of families suspected of von Hippel-Lindau disease (vHL), as well as recommendations for prophylactic surveillance for vHL patients. The guideline has been composed by the Danish Coordination Group...... for vHL which is comprised of Danish doctors and specialists interested in vHL. The recommendations are based on longstanding clinical experience, Danish original research, and extensive review of the international literature. vHL is a hereditary multi-tumour disease caused by germline mutations...... of the disease, and/or in individuals with a vHL-associated manifestation; i.e. a hemangioblastoma in the retina or the central nervous system, familial or bilateral pheochromocytomas, familial, multiple, or early onset renal cell carcinomas, and in individuals with an endolymphatic sac tumour in the inner ear...

  13. Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 HL-60HL-60 HL-60 cells by a natural diterpene ester from Daphne mucronata

    Directory of Open Access Journals (Sweden)

    R Yazdanparast

    2011-05-01

    Full Text Available "n  "nBackground and the purpose of the study: Gnidilatimonoein (Gn, a new diterpene ester from Daphne mucronata, possesses strong anti-metastasis and anti-tumor activities. In this study, its apoptosis and differentiation capabilities were evaluated by using the leukemia HL-60 cell line. "nMaterial and methods: Cell prolifaration inhibition was estimated by MTT assay. The occurrence of apoptosis was evaluated by EtBr/AO double staining technique, cell cycle analyses and detection of apoptotic cells by Annexin V-FITC and propodium iodide (PI. Differentiation of the cells was determined by NBT reduction assay and the expression of specific cell surface markers such as CD14 and CD11b, were analyzed by flow cytometry.   "nResults: The drug decreased the growth of the cells dose- and time- dependently and the IC50 was found to be 1.3 µM. Our data suggested that Gn induced both monocytic differentiation  and apoptosis among HL-60 cells. In addition, cell cycle analyses showed an increase in G1 phase population by 24 hrs, which was gradually replaced by Sub-G1 cell population (apoptotic cells by 72 hrs. "nConclusion: Based on these data, the Gn-treated HL-60 cells displayed differentiation-dependent apoptosis. Thus, Gn might be a good candidate for differentiation therapy of leukemia, pending full biological evaluation of the compound among the wide array of leukemia cells. "nevaluation of the compound among the wide array of leukemia cells.

  14. First Divertor Operation on the HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    YANG Qing-Wei; CAO Zeng; LI Xiao-Dong; MAO Wei-Cheng; ZHOU Cai-Pin; WANG En-Yao; YAN Jian-Cheng; LIU Yong; HL-2A team; DING Xuan-Tong; YAN Long-Wen; XUAN Wei-Min; LIU De-Quan; CHEN Liao-Yuan; SONG Xian-Ming; YUAN Bao-Shan; ZHANG Jin-Hua

    2004-01-01

    @@ HL-2A device is the first divertor tokamak in China. One of its main subjects is to study the features of the divertor plasma. In the last campaign, the first divertor configuration has been achieved and sustained on the HL-2A tokamak. Here we give a brief description about the HL-2A tokamak, diagnostics arrangements, and the equilibrium analysis results on divertor configuration. The main results of divertor experiments are also presented.

  15. Does HL7 Go towards an Architecture Standard?

    Science.gov (United States)

    Oemig, Frank; Blobel, Bernd

    2005-01-01

    Starting as a rather simple message standard to be used within hospitals, the scope of HL7 has been extended to covering all domains and institutions in health. The most important development of the HL7 standard set was its development towards a model-based message specification methodology and the further movement towards a unified development process: HL7 Version 3. The focus was design for interoperability, which is also the driving aspect of architectural standards such as OMG's CORBA or the CEN EN 13606 Electronic Health Record Communication. The paper gives an overview about the HL7 standard set, comparing it with the principles of advanced information systems architecture.

  16. Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells

    Directory of Open Access Journals (Sweden)

    Duan Yingli

    2010-05-01

    Full Text Available Abstract Background Pyk2 is a non-receptor cytoplasmic tyrosine kinase that belongs to the focal adhesion kinase family and has been implicated in neutrophil spreading and respiratory burst activity caused by TNF-α. However, the role of Pyk2 in neutrophil migration is incompletely defined. In this study, we tested the hypothesis that Pyk2 regulates the migration of neutrophil-like differentiated HL-60 cells subsequent to β2-integrin mediated cell adhesion. Methods HL-60 cells were induced to differentiate into neutrophil-like cells (dHL60 by incubation in medium containing 1.25% DMSO for up to 4 days. Pyk2 expression and tyrosine phosphorylation was measured by Western blot analysis. Adhesion of dHL60 cells to plated fibrinogen was measured by residual myeloperoxidase activity. dHL60 cell migration was evaluated using a 96-well chemoTx chamber. Results Western blot analysis demonstrated that hematopoietic Pyk2 was predominantly expressed after HL60 cell differentiation. Pyk2 was tyrosine phosphorylated upon adhesion of dHL60 cells to plated fibrinogen in the presence of fMLP. By contrast, tyrosine phosphorylation of Pyk2 was insignificant in dHL60 cells treated in suspension with fMLP. Antibodies against CD18 blocked both phosphorylation of Pyk2 and adhesion of dHL60 cells to fibrinogen, demonstrating that phosphorylation of Pyk2 was β2-integrin dependent. TAT-Pyk2-CT, a dominant negative fusion protein in which the TAT protein transduction domain was fused to the c-terminal Pyk2, attenuated fMLP-stimulated spreading, migration and phosphorylation of endogenous Pyk2 without blocking adhesion of dHL-60 cells to fibrinogen. Similarly, silencing of Pyk2 expression by siRNA in dHL60 cells also attenuated dHL60 cell migration caused by fMLP. Phospho-Pyk2 was evenly distributed around cell membrane circumferentially in unstimulated dHL-60 cells adherent to plated fibrinogen. In dHL60 cells treated with fMLP to cause cell spreading and polarization

  17. Wavelets and the lifting scheme

    DEFF Research Database (Denmark)

    la Cour-Harbo, Anders; Jensen, Arne

    2009-01-01

    The objective of this article is to give a concise introduction to the discrete wavelet transform (DWT) based on a technique called lifting. The lifting technique allows one to give an elementary, but rigorous, definition of the DWT, with modest requirements on the reader. A basic knowledge...... of linear algebra and signal processing will suffice. The lifting based definition is equivalent to the usual filer bank based definition of the DWT. The article does not discuss applications in any detail. The reader is referred to other articles in this collection....

  18. HYDRAULICS, LOUISA COUNTY, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulic data include spatial datasets and data tables necessary for documenting the hydraulic analysis for estimating flood stages for a flood insurance study. It...

  19. Hydraulic Hybrid Vehicles

    Science.gov (United States)

    EPA and the United Parcel Service (UPS) have developed a hydraulic hybrid delivery vehicle to explore and demonstrate the environmental benefits of the hydraulic hybrid for urban pick-up and delivery fleets.

  20. Lifting strength in two-person teamwork.

    Science.gov (United States)

    Lee, Tzu-Hsien

    2016-01-01

    This study examined the effects of lifting range, hand-to-toe distance, and lifting direction on single-person lifting strengths and two-person teamwork lifting strengths. Six healthy males and seven healthy females participated in this study. Two-person teamwork lifting strengths were examined in both strength-matched and strength-unmatched groups. Our results showed that lifting strength significantly decreased with increasing lifting range or hand-to-toe distance. However, lifting strengths were not affected by lifting direction. Teamwork lifting strength did not conform to the law of additivity for both strength-matched and strength-unmatched groups. In general, teamwork lifting strength was dictated by the weaker of the two members, implying that weaker members might be exposed to a higher potential danger in teamwork exertions. To avoid such overexertion in teamwork, members with significantly different strength ability should not be assigned to the same team.

  1. Introduction to the HL-LHC Project

    CERN Document Server

    Rossi , L

    2015-01-01

    The Large Hadron Collider (LHC) is one of largest scientific instruments ever built. It has been exploring the new energy frontier since 2010, gathering a global user community of 7,000 scientists. To extend its discovery potential, the LHC will need a major upgrade in the 2020s to increase its luminosity (rate of collisions) by a factor of five beyond its design value and the integrated luminosity by a factor of ten. As a highly complex and optimized machine, such an upgrade of the LHC must be carefully studied and requires about ten years to implement. The novel machine configuration, called High Luminosity LHC (HL-LHC), will rely on a number of key innovative technologies, representing exceptional technological challenges, such as cutting-edge 11–12 tesla superconducting magnets, very compact superconducting cavities for beam rotation with ultra-precise phase control, new technology for beam collimation and 300-meter-long high-power superconducting links with negligible energy dissipation. HL-LHC federa...

  2. On the generalized lifting problem

    Directory of Open Access Journals (Sweden)

    Giorgio Bolondi

    1993-05-01

    Full Text Available We construct curves for which the generalized lifting property does not hold, with high degree. We discuss the behaviour of the Hilbert function of the general plane section of these curves.

  3. Nordic noir and lifted localities

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    What I do here is to draw attention to a particular visual quality of recent Nordic noir and to relate the visuality of TV-drama to what I – with a term borrowed from Roland Robertson – dub lifted localites.......What I do here is to draw attention to a particular visual quality of recent Nordic noir and to relate the visuality of TV-drama to what I – with a term borrowed from Roland Robertson – dub lifted localites....

  4. Noise Simulations of the High-Lift Common Research Model

    Science.gov (United States)

    Lockard, David P.; Choudhari, Meelan M.; Vatsa, Veer N.; O'Connell, Matthew D.; Duda, Benjamin; Fares, Ehab

    2017-01-01

    The PowerFLOW(TradeMark) code has been used to perform numerical simulations of the high-lift version of the Common Research Model (HL-CRM) that will be used for experimental testing of airframe noise. Time-averaged surface pressure results from PowerFLOW(TradeMark) are found to be in reasonable agreement with those from steady-state computations using FUN3D. Surface pressure fluctuations are highest around the slat break and nacelle/pylon region, and synthetic array beamforming results also indicate that this region is the dominant noise source on the model. The gap between the slat and pylon on the HL-CRM is not realistic for modern aircraft, and most nacelles include a chine that is absent in the baseline model. To account for those effects, additional simulations were completed with a chine and with the slat extended into the pylon. The case with the chine was nearly identical to the baseline, and the slat extension resulted in higher surface pressure fluctuations but slightly reduced radiated noise. The full-span slat geometry without the nacelle/pylon was also simulated and found to be around 10 dB quieter than the baseline over almost the entire frequency range. The current simulations are still considered preliminary as changes in the radiated acoustics are still being observed with grid refinement, and additional simulations with finer grids are planned.

  5. Feedback Control for Plasma Position on HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    LIBo; SONGXianming; LILi; LIULi; WANGMinghong; FANMingjie; CHENLiaoyuan; YAOLieying; YANGQingwei

    2003-01-01

    HL-2A is a tokamak with closed divertor. It had been built at the end of 2002 and began to discharge from then on. To further study plasma discharges in HL-2A, a feedback control system (FBCS) for plasma position bad been developed in 2003.

  6. Surveillance in von Hippel-Lindau disease (vHL)

    DEFF Research Database (Denmark)

    Poulsen, Marie Louise Mølgaard; Budtz-Jørgensen, E; Bisgaard, M L

    2010-01-01

    for the patient. Also, pre-symptomatic surveillance increased cumulative incidence of clinical vHL diagnosis from 46% to 72% and from 89% to 94% by age 30 and 50 years, respectively. The present results promote optimization of surveillance, expectantly improving clinical vHL outcomes....

  7. HL-2A Control System and its Discharge Management

    Institute of Scientific and Technical Information of China (English)

    SONGXianming; JIANGChao; LIQiang; LIBo; FANMinNie; CHENLiaoyuan; LUOCuiwen; WANGMinghong; TANGFangqun; LIULi; MAOSuying; LIFeidi

    2002-01-01

    HL-2A is a divertor tokamak with noncircular plasma cross-section, it can operate in single-null or double-null plasma discharges.The toroidal and poloidal coils, vacuum vessel and supporting structure of HL-2A come from the former ASDEX, Germany.

  8. Von Hippel-Lindau disease (vHL)

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Bisgaard, Søs Marie Luise; Harbud, Vibeke

    2013-01-01

    These clinical guidelines outline the criteria and recommendations for diagnostic and genetic work-up of families suspected of von Hippel-Lindau disease (vHL), as well as recommendations for prophylactic surveillance for vHL patients. The guideline has been composed by the Danish Coordination Gro...

  9. [Transfection of HL-60 cells by Venus lentiviral vector].

    Science.gov (United States)

    Li, Zheng; Hu, Shao-Yan; Cen, Jian-Nong; Chen, Zi-Xing

    2013-06-01

    In order to study the potential of Venus, lentiviral vector, applied to acute myeloid leukemia, the recombinant vector Venus-C3aR was transfected into 293T packing cells by DNA-calcium phosphate coprecipitation. All virus stocks were collected and transfected into HL-60, the GFP expression in HL-60 cells was measured by flow cytometry. The expression level of C3aR1 in transfected HL-60 cells was identified by RT-PCR and flow cytometry. The lentiviral toxicity on HL-60 was measured by using CCK-8 method and the ability of cell differentiation was observed. The results indicated that the transfection efficacy of lentiviral vector on HL-60 cells was more than 95%, which meets the needs for further study. C3aR1 expression on HL-60 cells increased after being transfected with recombinant lentiviral vector. Before and after transfection, the proliferation and differentiation of cells were not changed much. It is concluded that the lentiviral vector showed a high efficacy to transfect AML cells and can be integrated in genome of HL-60 cells to realize the stable expression of interest gene. Meanwhile, lentiviral vector can not affect HL-60 cell ability to proliferate and differentiate.

  10. On planet formation in HL Tau

    CERN Document Server

    Dipierro, Giovanni; Laibe, Guillaume; Hirsh, Kieran; Cerioli, Alice; Lodato, Giuseppe

    2015-01-01

    We explain the axisymmetric gaps seen in recent long-baseline observations of the HL Tau protoplanetary disc with the Atacama Large Millimetre/Submillimetre Array (ALMA) as being due to the different response of gas and dust to embedded planets in protoplanetary discs. We perform global, three dimensional dusty smoothed particle hydrodynamics calculations of multiple planets embedded in dust/gas discs which successfully reproduce most of the structures seen in the ALMA image. We find a best match to the observations using three embedded planets with masses of 0.2, 0.27 and 0.55 $M_{\\rm J}$ in the three main gaps observed by ALMA, though there remain uncertainties in the exact planet masses from the disc model.

  11. Effect of 8-Chloroadenosine on Undifferentiatied HL-60 Cell Line

    Institute of Scientific and Technical Information of China (English)

    CUIJing-rong; HUIYu; XIANGYou-qing; ZHANGLi-he

    2003-01-01

    Aim To study the effect of 8-chloroadenosine (8-CA)on undifferentiatied HL-60 cell line. Methods The IC50 of cancer cell proliferation was determined using a microculture plate reader at 570 nm (MTT) and 540 nm (SRB).Morphology of HL-60 cells was observed under a scanning electron microscope and a transmission electron microscope. The differentiation of HL-60 cells was examined by nitro blue tetrazolium reduction (NBT) and acid phosphatase assay. The cycle of HL-60 cells was analyzed by flow cytometry. Results 8-CA inhibited proliferation of eight human cancer cell lines.The IC50 ranked in the following order; KB (0.05 μmol·L-1 ) < HL-60 (0.25 μmol·L-1) < Bel-7402 (0.56μmol·L-1 )< MCF-7 (0.65μmol·L-1) < HCT (0.79 μmol·L-1) < HeLa (0.89μmol·L-1) < BGC-823 ( 1.149μmol·L-1) HL-60 cell surface shortened, and the shape of HL-60 cells nuclei changed to kidney-shaped, horse shoe-shaped and bilob ated after treatment with 8-CA. Meanwhile, 8-CA promoted NBT reduction and increased activity of acid phosphatase in HL-60 ceils in a time and concentration-dependent manner. Flow cytometry analysis indicated that 8-CA induced an appreciable increase of the cell population in G1 phase with a marked reduction in S phase. Conclusion 8-CA can induce differentiation of HL-60 cells and block the cells at G1 phase, thus inhibiting proliferation of HL-60 cells.

  12. Mist lift analysis summary report

    Energy Technology Data Exchange (ETDEWEB)

    Davenport, R.L.

    1980-09-01

    The mist flow open-cycle OTEC concept proposed by S.L. Ridgway has much promise, but the fluid mechanics of the mist flow are not well understood. The creation of the mist and the possibility of droplet growth leading to rainout (when the vapor can no longer support the mist) are particularly troublesome. This report summarizes preliminary results of a numerical analysis initiated at SERI in FY79 to study the mist-lift process. The analysis emphasizes the mass transfer and fluid mechanics of the steady-state mist flow and is based on one-dimensional models of the mist flow developed for SERI by Graham Wallis. One of Wallis's models describes a mist composed of a single size of drops and another considers several drop sizes. The latter model, further developed at SERI, considers a changing spectrum of discrete drop sizes and incorporates the mathematics describing collisions and growth of the droplets by coalescence. The analysis results show that under conditions leading to maximum lift in the single-drop-size model, the multigroup model predicts significantly reduced lift because of the growth of droplets by coalescence. The predicted lift height is sensitive to variations in the mass flow rate and inlet pressure. Inclusion of a coasting section, in which the drops would rise ballistically without change in temperature, may lead to increased lift within the existing range of operation.

  13. CERN lifting equipment use authorisation

    CERN Multimedia

    2004-01-01

    Updated procedures to obtain authorisation to use lifting equipment at CERN have been put in place. As a general rule, lifting equipment at CERN may be operated only by qualified staff, i.e. those who have had intensive training in and adequate experience of using such equipment. However, for straightforward recurrent lifting operations, the Organization issues authorisations to operate lifting equipment at CERN to people who have followed a suitable course of training. The authorisation to use lifting equipment is valid for five years. More information about the procedures will be found at the following addresses: CERN Staff: http://sc-gs.web.cern.ch/sc-gs/gs_ms/ms/freq%20topics/te_mc_FT_staff.htm Associated members of the personnel (users, ...) : http://sc-gs.web.cern.ch/sc-gs/gs_ms/ms/freq%20topics/te_mc_FT_users.htm Contractors personnel : http://sc-gs.web.cern.ch/sc-gs/gs_ms/ms/freq%20topics/te_mc_FT_peoplefromext.htm In case of questions, please send a message to: securite...

  14. Normalized lift: an energy interpretation of the lift coefficient simplifies comparisons of the lifting ability of rotating and flapping surfaces.

    Science.gov (United States)

    Burgers, Phillip; Alexander, David E

    2012-01-01

    For a century, researchers have used the standard lift coefficient C(L) to evaluate the lift, L, generated by fixed wings over an area S against dynamic pressure, ½ρv(2), where v is the effective velocity of the wing. Because the lift coefficient was developed initially for fixed wings in steady flow, its application to other lifting systems requires either simplifying assumptions or complex adjustments as is the case for flapping wings and rotating cylinders.This paper interprets the standard lift coefficient of a fixed wing slightly differently, as the work exerted by the wing on the surrounding flow field (L/ρ·S), compared against the total kinetic energy required for generating said lift, ½v(2). This reinterpreted coefficient, the normalized lift, is derived from the work-energy theorem and compares the lifting capabilities of dissimilar lift systems on a similar energy footing. The normalized lift is the same as the standard lift coefficient for fixed wings, but differs for wings with more complex motions; it also accounts for such complex motions explicitly and without complex modifications or adjustments. We compare the normalized lift with the previously-reported values of lift coefficient for a rotating cylinder in Magnus effect, a bat during hovering and forward flight, and a hovering dipteran.The maximum standard lift coefficient for a fixed wing without flaps in steady flow is around 1.5, yet for a rotating cylinder it may exceed 9.0, a value that implies that a rotating cylinder generates nearly 6 times the maximum lift of a wing. The maximum normalized lift for a rotating cylinder is 1.5. We suggest that the normalized lift can be used to evaluate propellers, rotors, flapping wings of animals and micro air vehicles, and underwater thrust-generating fins in the same way the lift coefficient is currently used to evaluate fixed wings.

  15. Normalized lift: an energy interpretation of the lift coefficient simplifies comparisons of the lifting ability of rotating and flapping surfaces.

    Directory of Open Access Journals (Sweden)

    Phillip Burgers

    Full Text Available For a century, researchers have used the standard lift coefficient C(L to evaluate the lift, L, generated by fixed wings over an area S against dynamic pressure, ½ρv(2, where v is the effective velocity of the wing. Because the lift coefficient was developed initially for fixed wings in steady flow, its application to other lifting systems requires either simplifying assumptions or complex adjustments as is the case for flapping wings and rotating cylinders.This paper interprets the standard lift coefficient of a fixed wing slightly differently, as the work exerted by the wing on the surrounding flow field (L/ρ·S, compared against the total kinetic energy required for generating said lift, ½v(2. This reinterpreted coefficient, the normalized lift, is derived from the work-energy theorem and compares the lifting capabilities of dissimilar lift systems on a similar energy footing. The normalized lift is the same as the standard lift coefficient for fixed wings, but differs for wings with more complex motions; it also accounts for such complex motions explicitly and without complex modifications or adjustments. We compare the normalized lift with the previously-reported values of lift coefficient for a rotating cylinder in Magnus effect, a bat during hovering and forward flight, and a hovering dipteran.The maximum standard lift coefficient for a fixed wing without flaps in steady flow is around 1.5, yet for a rotating cylinder it may exceed 9.0, a value that implies that a rotating cylinder generates nearly 6 times the maximum lift of a wing. The maximum normalized lift for a rotating cylinder is 1.5. We suggest that the normalized lift can be used to evaluate propellers, rotors, flapping wings of animals and micro air vehicles, and underwater thrust-generating fins in the same way the lift coefficient is currently used to evaluate fixed wings.

  16. Design and Implementation of HL7 V3 Gateway

    Institute of Scientific and Technical Information of China (English)

    ZHU Sui-hui; RAO Ni-ni

    2005-01-01

    Although the health data exchange standard of Health Level 7(HL7) V2.x (Version 2.0-2.5) has been widely used in hospital and has served well in these few years, the process that hospitals apply the standard of data transfer is very difficult. Because there is no explicit methodology in the HL7 V2.x development process, the gateway design is very complex. However, V3 strives to improve the V2 process and its outcomes. In this paper, the authors present an HL7 V3 gateway design based on the Web Services which can solve the problems of the HL7 V2.x. Web Services is an information exchange protocol regardless of the implementation platform, and is currently the main technology in enterprise application integration (EAI). We firstly introduce how to build HL7 V3 gateway with Web Services, then focus on the design of HL7 gateway, finally realize the parsing and transmission of HL7 V3 message.

  17. Evaluation of the effectiveness of a water lift system in the sinus membrane-lifting operation as a sinus surgical instrument.

    Science.gov (United States)

    Kim, Dae Y; Itoh, Yusaku; Kang, Tae H

    2012-08-01

    The effectiveness of a Water Lift System in the sinus membrane-lifting operation was examined. This investigation focused on the capability of this equipment to reduce the risk of Schneiderian membrane perforation. A preliminary clinical study on the use of the Water Lift System in sinus membrane elevation to place implants through the sinus floor was conducted. A total of 70 sinus membrane-lifting operations were performed on patients with various bone heights ranging from 1.2 to 9.9 mm (most commonly in the range of 4-6 mm) through the lateral approach (four cases) or the crestal approach (66 cases). In all of the cases performed using the lateral approach, sinus membrane perforation did not occur. In the 66 cases performed using the crestal approach, Schneiderian membrane tearing occurred in two cases. The membrane tearing occurred during elevation of the Schneiderian membrane but not when a hole was drilled to access the Schneiderian membrane. One case of membrane tearing resulted from previous inflammation in the maxillary sinus, and the other case of membrane tearing was caused by application of excessive hydraulic pressure. In addition, similar outcomes were obtained and no microbial infections were observed in a total of 68 successful cases. In this study, the Water Lift System was confirmed to effectively reduce the risk of Schneiderian membrane perforation during the sinus membrane-lifting operation. We conclude that the Water Lift System deserves to be considered as a sinus surgical instrument, which ensures safety in the sinus membrane-lifting operation. © 2010 Wiley Periodicals, Inc.

  18. Endoscopic brow lifts uber alles.

    Science.gov (United States)

    Patel, Bhupendra C K

    2006-12-01

    Innumerable approaches to the ptotic brow and forehead have been described in the past. Over the last twenty-five years, we have used all these techniques in cosmetic and reconstructive patients. We have used the endoscopic brow lift technique since 1995. While no one technique is applicable to all patients, the endoscopic brow lift, with appropriate modifications for individual patients, can be used effectively for most patients with brow ptosis. We present the nuances of this technique and show several different fixation methods we have found useful.

  19. Dystroglycan depletion inhibits the functions of differentiated HL-60 cells.

    Science.gov (United States)

    Martínez-Zárate, Alma Delia; Martínez-Vieyra, Ivette; Alonso-Rangel, Lea; Cisneros, Bulmaro; Winder, Steve J; Cerecedo, Doris

    2014-06-01

    Dystroglycan has recently been characterized in blood tissue cells, as part of the dystrophin glycoprotein complex but to date nothing is known of its role in the differentiation process of neutrophils. We have investigated the role of dystroglycan in the human promyelocytic leukemic cell line HL-60 differentiated to neutrophils. Depletion of dystroglycan by RNAi resulted in altered morphology and reduced properties of differentiated HL-60 cells, including chemotaxis, respiratory burst, phagocytic activities and expression of markers of differentiation. These findings strongly implicate dystroglycan as a key membrane adhesion protein involved in the differentiation process in HL-60 cells.

  20. Thermally Actuated Hydraulic Pumps

    Science.gov (United States)

    Jones, Jack; Ross, Ronald; Chao, Yi

    2008-01-01

    Thermally actuated hydraulic pumps have been proposed for diverse applications in which direct electrical or mechanical actuation is undesirable and the relative slowness of thermal actuation can be tolerated. The proposed pumps would not contain any sliding (wearing) parts in their compressors and, hence, could have long operational lifetimes. The basic principle of a pump according to the proposal is to utilize the thermal expansion and contraction of a wax or other phase-change material in contact with a hydraulic fluid in a rigid chamber. Heating the chamber and its contents from below to above the melting temperature of the phase-change material would cause the material to expand significantly, thus causing a substantial increase in hydraulic pressure and/or a substantial displacement of hydraulic fluid out of the chamber. Similarly, cooling the chamber and its contents from above to below the melting temperature of the phase-change material would cause the material to contract significantly, thus causing a substantial decrease in hydraulic pressure and/or a substantial displacement of hydraulic fluid into the chamber. The displacement of the hydraulic fluid could be used to drive a piston. The figure illustrates a simple example of a hydraulic jack driven by a thermally actuated hydraulic pump. The pump chamber would be a cylinder containing encapsulated wax pellets and containing radial fins to facilitate transfer of heat to and from the wax. The plastic encapsulation would serve as an oil/wax barrier and the remaining interior space could be filled with hydraulic oil. A filter would retain the encapsulated wax particles in the pump chamber while allowing the hydraulic oil to flow into and out of the chamber. In one important class of potential applications, thermally actuated hydraulic pumps, exploiting vertical ocean temperature gradients for heating and cooling as needed, would be used to vary hydraulic pressures to control buoyancy in undersea research

  1. Prototype HL-LHC magnet undergoes testing

    CERN Multimedia

    Corinne Pralavorio

    2016-01-01

    A preliminary short prototype of the quadrupole magnets for the High-Luminosity LHC has passed its first tests.   The first short prototype of the quadrupole magnet for the High Luminosity LHC. (Photo: G. Ambrosio (US-LARP and Fermilab), P. Ferracin and E. Todesco (CERN TE-MSC)) Momentum is gathering behind the High-Luminosity LHC (HL-LHC) project. In laboratories on either side of the Atlantic, a host of tests are being carried out on the various magnet models. In mid-March, a short prototype of the quadrupole magnet underwent its first testing phase at the Fermilab laboratory in the United States. This magnet is a pre-prototype of the quadrupole magnets that will be installed near to the ATLAS and CMS detectors to squeeze the beams before collisions. Six quadrupole magnets will be installed on each side of each experiment, giving a total of 24 magnets, and will replace the LHC's triplet magnets. Made of superconducting niobium-tin, the magnets will be more powerful than their p...

  2. Dieter Möhl (1936–2012)

    CERN Multimedia

    2012-01-01

    It is with great emotion and deep sadness that we learnt of the loss of our colleague and friend Dieter Möhl on 24 May. An accelerator physicist of world reputation, he made essential contributions to many projects at CERN and around the world. Here at CERN his name will remain forever linked with the success of the antiproton programme from its very beginning, but he also made substantial contributions to the FAIR project in Germany and to many other storage rings where beam cooling was an essential ingredient. His theoretical work was unique for the understanding, improvement and extension of beam cooling techniques to many accelerators and storage rings.   He was one of the pioneers who demonstrated by the Initial Cooling Experiment (ICE) that stochastic cooling was a viable proposition. This was essential for the approval of the CERN antiproton programme and its success.  Then, he was a leading member of the team which initiated and designed the Low Energy Antiproton Rin...

  3. Machine Protection Challenges for HL-LHC

    CERN Document Server

    Schmidt, R; Wenninger, J; Wollmann, D; Zerlauth, M

    2014-01-01

    LHC operation requires the flawless functioning of the machine protection systems. The energy stored in the beam was progressively increased beyond the 140 MJ range at the end of 2012 at 4 TeV/c. The further increase to more than 300 MJ expected for 2015 at 6.5 TeV/c should be possible with the existing protection systems. For HL-LHC additional failure modes need to be considered. The stored beam energy will increase by another factor of two with respect to nominal and a factor of five more than experienced so far. The maximum beta function in the high luminosity insertion regions will increase. It is planned to install crab cavities in the LHC to compensate for the loss in luminosity due to the crossing-angle. With crab cavities, sudden voltage decays within 100 µs after e.g. cavity quenches can lead to large transverse beam oscillations. Tracking simulations predict trajectory distortions of up to 1.5 σ after a sudden drop of the deflecting voltage in a single cavity. Protons in the halo with an energy of...

  4. [Inhibitory effect of 14-3-3ζ on the proliferation of HL-60 cells and HL-60/VCR cells].

    Science.gov (United States)

    Liang, Rong; Chen, Xie-Qun; Wang, Zhe; Xiong, Hua; Bai, Qing-Xian; Gao, Guang-Xun; Dong, Bao-Xia; Zhu, Hua-Feng

    2013-08-01

    This study was aimed to investigate the expression and role of 14-3-3ζ in the AML cell lines: sensitive HL-60 and drug-resistant HL-60/VCR cells. Semi-quantitative RT-PCR and Western blot were respectively used to examine the expression of mdr1 mRNA and Pgp in AML cell lines to validate the results of microarray. Western blot was performed to investigate the expression of Pgp, 14-3-3ζ, and anti-apoptosis protein BCL-2, MCL-1 proteins. Immunofluorescence assay was used to detect the subcellular location of 14-3-3ζ protein in HL-60 and HL-60/VCR cells by laser scanning confocal microscopy. Transduction with siRNA was used to silence 14-3-3ζ in AML cell lines. Cell count method and flow cytometry of cell cycle were used to analyze the changes of growth of AML cells. The results found that mdr1 mRNA and Pgp did not expressed in HL-60 cells, but significantly overexpressed in HL-60/VCR cells. Except 14-3-3σ, the expression of other subtypes of 14-3-3 was higher in HL-60/VCR cells than that in HL-60 cells, especially 14-3-3ζ. The higher expression of 14-3-3ζ, BCL-2, MCL-1 protein was observed in HL-60/VCR cells than that in HL-60 cells. These results were same results from gene chip. It was also noticed that 14-3-3ζ was located in the cytoplasma and nuclei of AML cell lines, especially over-expressed in HL-60/VCR cells. Furthermore, suppression of 14-3-3ζ by RNA interference resulted in inhibition of the proliferation of AML cells with decreased protein expression of BCL-2 and MCL-1, especially in HL-60/VCR cells. It is concluded that 14-3-3ζ plays an important role in proliferation of AML cells and associates with BCL-2 and MCL-1 expression. These results suggested that development of therapy targeting 14-3-3ζ may provide novel, effective strategies for refractory and relapsed AML.

  5. In vivo structure-function studies of human hepatic lipase: the catalytic function rescues the lean phenotype of HL-deficient (hl −/−) mice

    OpenAIRE

    Chen, Jeffrey; Kaiyala, Karl J.; Lam, Jennifer; Agrawal, Nalini; Nguyen, Lisa; Ogimoto, Kayoko; Spencer, Dean; Morton, Gregory J.; Schwartz, Michael W.; Dichek, Helén L.

    2015-01-01

    The lean body weight phenotype of hepatic lipase (HL)–deficient mice (hl −/−) suggests that HL is required for normal weight gain, but the underlying mechanisms are unknown. HL plays a unique role in lipoprotein metabolism performing bridging as well as catalytic functions, either of which could participate in energy homeostasis. To determine if both the catalytic and bridging functions or the catalytic function alone are required for the effect of HL on body weight, we studied (hl −/−) mice ...

  6. Prosthetic Hand Lifts Heavy Loads

    Science.gov (United States)

    Carden, James R.; Norton, William; Belcher, Jewell G.; Vest, Thomas W.

    1991-01-01

    Prosthetic hand designed to enable amputee to lift diverse heavy objects like rocks and logs. Has simple serrated end effector with no moving parts. Prosthesis held on forearm by system of flexible straps. Features include ruggedness, simplicity, and relatively low cost.

  7. Vibration of hydraulic machinery

    CERN Document Server

    Wu, Yulin; Liu, Shuhong; Dou, Hua-Shu; Qian, Zhongdong

    2013-01-01

    Vibration of Hydraulic Machinery deals with the vibration problem which has significant influence on the safety and reliable operation of hydraulic machinery. It provides new achievements and the latest developments in these areas, even in the basic areas of this subject. The present book covers the fundamentals of mechanical vibration and rotordynamics as well as their main numerical models and analysis methods for the vibration prediction. The mechanical and hydraulic excitations to the vibration are analyzed, and the pressure fluctuations induced by the unsteady turbulent flow is predicted in order to obtain the unsteady loads. This book also discusses the loads, constraint conditions and the elastic and damping characters of the mechanical system, the structure dynamic analysis, the rotor dynamic analysis and the system instability of hydraulic machines, including the illustration of monitoring system for the instability and the vibration in hydraulic units. All the problems are necessary for vibration pr...

  8. Handbook of hydraulic fluid technology

    CERN Document Server

    Totten, George E

    2011-01-01

    ""The Handbook of Hydraulic Fluid Technology"" serves as the foremost resource for designing hydraulic systems and for selecting hydraulic fluids used in engineering applications. Featuring new illustrations, data tables, as well as practical examples, this second edition is updated with essential information on the latest hydraulic fluids and testing methods. The detailed text facilitates unparalleled understanding of the total hydraulic system, including important hardware, fluid properties, and hydraulic lubricants. Written by worldwide experts, the book also offers a rigorous overview of h

  9. Recent Development of Data Acquisition System on HL-2A

    Institute of Scientific and Technical Information of China (English)

    阳洋; 陈燎原; 李强; 潘莉

    2005-01-01

    This paper introduced recent development of data acquisition system(DAS) on the HL-2A tokamak. The existing DAS has to be remodeled because of the evident improvement on HL-2A itself and the increasing amount of corresponding experimental data. First, the experimental network on HL-2A Tokamak as a communication center is described in detail. Secondly,"The File's Format & Criterion of Experimental Data on HL-2A Tokamak" as the core of the new software is also presented. Thirdly, not only a multi-screen image display system on HL-2A is discussed, but also the build-up of a new display wall system is dealt with. Finally, on the graphical WINDOWS platform and on the basis of the new Data File's Format & Criterion, the new software on HL-2A is described, including a new multi-layer database management program,a real-time processing program, a common interactive analytic processing program and a data post-processing program, which is now under development.

  10. HMG CoA Lyase (HL): Mutation detection and development of a bacterial expression system for screening the activity of mutant alleles from HL-deficient patients

    Energy Technology Data Exchange (ETDEWEB)

    Robert, M.F.; Ashmarina, L.; Poitier, E. [Hospital Ste-Justine, Montreal (Canada)] [and others

    1994-09-01

    HL catalyzes the last step of ketogenesis, and autosomal recessive HL deficiency in humans can cause episodes of hypoglycemia and coma. Structurally, HL is a dimer of identical 325-residue peptides which requires a reducing environment to maintain activity. We cloned the human and mouse HL cDNAs and genes and have performed mutation analysis on cells from 30 HL-deficient probands. Using SSCP and also genomic Southern analysis we have identified putative mutations on 53/60 alleles of these patients (88%). To date, we have found 20 mutations: 3 large deletions, 4 termination mutations, 5 frameshift mutations, and 8 missense mutations which we suspect to be pathogenic based on evolutionary conservation and/or our previous studies on purified HL protein. We have also identified 3 polymorphic variants. In order to directly test the activity of the missense mutations, we established a pGEX-based system, using a glutathione S transferase (GST)-HL fusion protein. Expressed wild-type GST-HL was insoluble. We previously located a reactive Cys at the C-terminus of chicken HL which is conserved in human HL. We produced a mutant HL peptide, C323S, which replaced Cys323 with Ser. Purified C323S is soluble and has similar kinetics to wild-type HL. C323S-containing GST-HL is soluble and enzymatically active. We are cloning and expressing the 8 missense mutations.

  11. The behavior of tillage tools with acute and obtuse lift angles

    Energy Technology Data Exchange (ETDEWEB)

    Abbaspour-Fard, M. H.; Hoseini, S. A.; Agkhani, M. H.; Sharifi, A.

    2014-06-01

    An experimental investigation was conducted to study the trend of draft force against forward speed and working depth for a range of lift angles beyond acute angles for a simple plane tillage tool. The experiments were performed in an indoor soil bin facility equipped with a tool carriage and a soil preparation unit propelled by an integrated hydraulic power system. The system was also equipped with electronic instrumentation including an Extended Octagonal Ring Transducer (EORT) and a data logger. The factorial experiment (4 × 3 × 3) with three replications was used based on Randomized Complete Block Design (RCBD). The independent variables were lift angle of the blade (45, 70, 90 and 120 degree centigrade), forward speed (2, 4 and 6 km h{sup -}1) and working depth (10, 25 and 40 cm). The variance analysis for the draft force shows that all independent variables affect the draft force at 1% level of significance. The trend of the draft force against working depth and forward speed had almost a linear increase. However, the trend of the draft force against the lift angle is reversed for lift angles > 90 degree centigrade. This finding, conflicts with the results of analytical and numerical studies which extrapolate the results achieved for acute lift angles to obtuse lift angles and have not been reported experimentally. (Author)

  12. The behavior of tillage tools with acute and obtuse lift angles

    Directory of Open Access Journals (Sweden)

    Mohammad Hossein Abbaspour-Fard

    2014-01-01

    Full Text Available An experimental investigation was conducted to study the trend of draft force against forward speed and working depth for a range of lift angles beyond acute angles for a simple plane tillage tool. The experiments were performed in an indoor soil bin facility equipped with a tool carriage and a soil preparation unit propelled by an integrated hydraulic power system. The system was also equipped with electronic instrumentation including an Extended Octagonal Ring Transducer (EORT and a data logger. The factorial experiment (4×3×3 with three replications was used based on Randomized Complete Block Design (RCBD. The independent variables were lift angle of the blade (45, 70, 90 and 120°, forward speed (2, 4 and 6 km h-1 and working depth (10, 25 and 40 cm. The variance analysis for the draft force shows that all independent variables affect the draft force at 1% level of significance. The trend of the draft force against working depth and forward speed had almost a linear increase. However, the trend of the draft force against the lift angle is reversed for lift angles >90. This finding, conflicts with the results of analytical and numerical studies which extrapolate the results achieved for acute lift angles to obtuse lift angles and have not been reported experimentally.

  13. 49 CFR 37.203 - Lift maintenance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Lift maintenance. 37.203 Section 37.203... DISABILITIES (ADA) Over-the-Road Buses (OTRBs) § 37.203 Lift maintenance. (a) The entity shall establish a system of regular and frequent maintenance checks of lifts sufficient to determine if they are...

  14. 30 CFR 57.16016 - Lift trucks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lift trucks. 57.16016 Section 57.16016 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... § 57.16016 Lift trucks. Fork and other similar types of lift trucks shall be operated with the: (a...

  15. 30 CFR 56.16016 - Lift trucks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lift trucks. 56.16016 Section 56.16016 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND....16016 Lift trucks. Fork and other similar types of lift trucks shall be operated with the— (a) Upright...

  16. Protect Your Back: Guidelines for Safer Lifting.

    Science.gov (United States)

    Cantu, Carolyn O.

    2002-01-01

    Examines back injury in teachers and child care providers; includes statistics, common causes of back pain (improper alignment, improper posture, improper lifting, and carrying), and types of back pain (acute and chronic). Focuses on preventing back injury, body mechanics for lifting and carrying, and proper lifting and carrying of children. (SD)

  17. IT-Tools Concept for Simulation and Design of Water Hydraulic Mechatronic Test Facilities for Motion Control and Operation in Environmentally Sensitive Application Areas

    DEFF Research Database (Denmark)

    Conrad, Finn; Pobedza, J.; Sobczyk, A.

    2004-01-01

    This paper presents a proposed IT-Tools concept for modeling, simulation, analysis and design of water hydraulic actuators for motion control of machines, lifts, cranes and robots. The designed test rigs have tap water hydraulic components of the Danfoss Nessie® product family and equipped...

  18. The Effect of Lifting Speed on Cumulative and Peak Biomechanical Loading for Symmetric Lifting Tasks

    Directory of Open Access Journals (Sweden)

    Kasey O. Greenland

    2013-06-01

    Conclusion: Based on peak values, BCF is highest for fast speeds, but the BCF cumulative loading is highest for slow speeds, with the largest difference between fast and slow lifts. This may imply that a slow lifting speed is at least as hazardous as a fast lifting speed. It is important to consider the duration of lift when determining risks for back and shoulder injuries due to lifting and that peak values alone are likely not sufficient.

  19. First-Order Twistor Lifts

    Directory of Open Access Journals (Sweden)

    Simões BrunoAscenso

    2010-01-01

    Full Text Available The use of twistor methods in the study of Jacobi fields has proved quite fruitful, leading to a series of results. L. Lemaire and J. C. Wood proved several properties of Jacobi fields along harmonic maps from the two-sphere to the complex projective plane and to the three- and four-dimensional spheres, by carefully relating the infinitesimal deformations of the harmonic maps to those of the holomorphic data describing them. In order to advance this programme, we prove a series of relations between infinitesimal properties of the map and those of its twistor lift. Namely, we prove that isotropy and harmonicity to first order of the map correspond to holomorphicity to first order of its lift into the twistor space, relatively to the standard almost complex structures and . This is done by obtaining first-order analogues of classical twistorial constructions.

  20. Dimethylsulfoxide exposure modulates HL-60 cell rolling interactions.

    Science.gov (United States)

    Gee, David J; Wright, L Kate; Zimmermann, Jonathan; Cole, Kayla; Soule, Karen; Ubowski, Michelle

    2012-08-01

    Human leukaemic HL-60 cells are widely used for studying interactions involving adhesion molecules [e.g. P-selectin and PSGL-1 (P-selectin glycoprotein ligand-1)] since their rolling behaviour has been shown to mimic the dynamics of leucocyte rolling in vitro. HL-60 cells are neutrophilic promyelocytes that can undergo granulocytic differentiation upon exposure to compounds such as DMSO (dimethylsulfoxide). Using a parallel plate flow chamber functionalized with recombinant P-selectin-Fc chimaera, undifferentiated and DMSO-induced (48, 72 and 96 h) HL-60 cells were assayed for rolling behaviour. We found that depending on P-selectin incubation concentration, undifferentiated cells incurred up to a 6-fold increase in rolling velocity while subjected to an approximately 10-fold increase in biologically relevant shear stress. HL-60 cells exposed to DMSO for up to 72 h incurred up to a 3-fold increase in rolling velocity over the same shear stress range. Significantly, cells exposed for up to 96 h incurred up to a 9-fold decrease in rolling velocity, compared with undifferentiated HL-60 cells. Although cell surface and nuclear morphological changes were evident upon exposure to DMSO, flow cytometric analysis revealed that PSGL-1 expression was unchanged, irrespective of treatment duration. The results suggest that DMSO-treated HL-60 cells may be problematic as a substitute for neutrophils for trafficking studies during advanced stages of the LAC (leucocyte adhesion cascade). We suggest that remodelling of the cell surface during differentiation may affect rolling behaviour and that DMSO-treated HL-60 cells would behave differently from the normal leucocytes during inflammatory response in vivo.

  1. Lifting quasianalytic mappings over invariants

    CERN Document Server

    Rainer, Armin

    2010-01-01

    Let $\\rho : G \\to \\operatorname{GL}(V)$ be a rational finite dimensional complex representation of a reductive linear algebraic group $G$, and let $\\sigma_1,\\ldots,\\sigma_n$ be a system of generators of the algebra of invariant polynomials $\\mathbb{C}[V]^G$. We study the problem of lifting mappings $f : \\mathbb{R}^q \\supseteq U \\to \\sigma(V) \\subseteq \\mathbb{C}^n$ over the mapping of invariants $\\sigma=(\\sigma_1,\\ldots,\\sigma_n) : V \\to \\sigma(V)$. Note that $\\sigma(V)$ can be identified with the categorical quotient $V /\\!\\!/ G$ and its points correspond bijectively to the closed orbits in $V$. We prove that, if $f$ belongs to a quasianalytic subclass $\\mathcal{C} \\subseteq C^\\infty$ satisfying some mild closedness properties which guarantee resolution of singularities in $\\mathcal{C}$ (e.g.\\ the real analytic class), then $f$ admits a lift of the same class $\\mathcal{C}$ after desingularization by local blow-ups and local power substitutions. As a consequence we show that $f$ itself allows for a lift which...

  2. Bone marrow-derived HL mitigates bone marrow-derived CETP-mediated decreases in HDL in mice globally deficient in HL and the LDLr.

    Science.gov (United States)

    Hime, Neil J; Black, Audrey S; Bonnet, David J; Curtiss, Linda K

    2014-09-01

    The objective of this study was to determine the combined effects of HL and cholesteryl ester transfer protein (CETP), derived exclusively from bone marrow (BM), on plasma lipids and atherosclerosis in high-fat-fed, atherosclerosis-prone mice. We transferred BM expressing these proteins into male and female double-knockout HL-deficient, LDL receptor-deficient mice (HL(-/-)LDLr(-/-)). Four BM chimeras were generated, where BM-derived cells expressed 1) HL but not CETP, 2) CETP and HL, 3) CETP but not HL, or 4) neither CETP nor HL. After high-fat feeding, plasma HDL-cholesterol (HDL-C) was decreased in mice with BM expressing CETP but not HL (17 ± 4 and 19 ± 3 mg/dl, female and male mice, respectively) compared with mice with BM expressing neither CETP nor HL (87 ± 3 and 95 ± 4 mg/dl, female and male mice, respectively, P HL mitigated this CETP-mediated decrease in HDL-C. BM-derived CETP decreased the cholesterol component of HDL particles and increased plasma cholesterol. BM-derived HL mitigated these effects of CETP. Atherosclerosis was not significantly different between BM chimeras. These results suggest that BM-derived HL mitigates the HDL-lowering, HDL-modulating, and cholesterol-raising effects of BM-derived CETP and warrant further studies to characterize the functional properties of these protein interactions.

  3. Generalised Eisenhart lift of the Toda chain

    Energy Technology Data Exchange (ETDEWEB)

    Cariglia, Marco, E-mail: marco@iceb.ufop.br [DEFIS, Universidade Federal de Ouro Preto, Campus Morro do Cruzeiro, 35400-000 Ouro Preto, MG (Brazil); Gibbons, Gary, E-mail: g.w.gibbons@damtp.cam.ac.uk [DAMTP, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA (United Kingdom)

    2014-02-15

    The Toda chain of nearest neighbour interacting particles on a line can be described both in terms of geodesic motion on a manifold with one extra dimension, the Eisenhart lift, or in terms of geodesic motion in a symmetric space with several extra dimensions. We examine the relationship between these two realisations and discover that the symmetric space is a generalised, multi-particle Eisenhart lift of the original problem that reduces to the standard Eisenhart lift. Such generalised Eisenhart lift acts as an inverse Kaluza-Klein reduction, promoting coupling constants to momenta in higher dimension. In particular, isometries of the generalised lift metric correspond to energy preserving transformations that mix coordinates and coupling constants. A by-product of the analysis is that the lift of the Toda Lax pair can be used to construct higher rank Killing tensors for both the standard and generalised lift metrics.

  4. Generalised Eisenhart lift of the Toda chain

    CERN Document Server

    Cariglia, Marco

    2013-01-01

    The Toda chain of nearest neighbour interacting particles on a line can be described both in terms of geodesic motion on a manifold with one extra dimension, the Eisenhart lift, or in terms of geodesic motion in a symmetric space with several extra dimensions. We examine the relationship between these two realisations and discover that the symmetric space is a generalised, multi-particle Eisenhart lift of the original problem, that reduces to the standard Eisenhart lift. Such generalised Eisenhart lift acts as an inverse Kaluza-Klein reduction, promoting coupling constants to momenta in higher dimension. In particular, isometries of the generalised lift metric correspond to energy preserving transformations that mix coordinates and coupling constants. A by-product of the analysis is that the lift of the Toda Lax pair can be used to construct higher rank Killing tensors for both the standard and generalised lift metrics.

  5. Lift enhancement by bats' dynamically changing wingspan

    Science.gov (United States)

    Wang, Shizhao; Zhang, Xing; He, Guowei; Liu, Tianshu

    2015-01-01

    This paper elucidates the aerodynamic role of the dynamically changing wingspan in bat flight. Based on direct numerical simulations of the flow over a slow-flying bat, it is found that the dynamically changing wingspan can significantly enhance the lift. Further, an analysis of flow structures and lift decomposition reveal that the elevated vortex lift associated with the leading-edge vortices intensified by the dynamically changing wingspan considerably contributed to enhancement of the time-averaged lift. The nonlinear interaction between the dynamically changing wing and the vortical structures plays an important role in the lift enhancement of a flying bat in addition to the geometrical effect of changing the lifting-surface area in a flapping cycle. In addition, the dynamically changing wingspan leads to the higher efficiency in terms of generating lift for a given amount of the mechanical energy consumed in flight. PMID:26701882

  6. 3-Hydroxy-3-methylglutaryl CoA lyase (HL): Mouse and human HL gene (HMGCL) cloning and detection of large gene deletions in two unrelated HL-deficient patients

    Energy Technology Data Exchange (ETDEWEB)

    Wang, S.P.; Robert, M.F.; Mitchell, G.A. [Hopital Sainte-Justine, Quebec (Canada)] [and others

    1996-04-01

    3-hydroxy-3-methylglutaryl CoA lyase (HL, EC 4.1.3.4) catalyzes the cleavage of 3-hydroxy-3-methylglutaryl CoA to acetoacetic acid and acetyl CoA, the final reaction of both ketogenesis and leucine catabolism. Autosomal-recessive HL deficiency in humans results in episodes of hypoketotic hypoglycemia and coma. Using a mouse HL cDNA as a probe, we isolated a clone containing the full-length mouse HL gene that spans about 15 kb of mouse chromosome 4 and contains nine exons. The promoter region of the mouse HL gene contains elements characteristic of a housekeeping gene: a CpG island containing multiple Sp1 binding sites surrounds exon 1, and neither a TATA nor a CAAT box are present. We identified multiple transcription start sites in the mouse HL gene, 35 to 9 bases upstream of the translation start codon. We also isolated two human HL genomic clones that include HL exons 2 to 9 within 18 kb. The mouse and human HL genes (HGMW-approved symbol HMGCL) are highly homologous, with identical locations of intron-exon junctions. By genomic Southern blot analysis and exonic PCR, was found 2 of 33 HL-deficient probands to be homozygous for large deletions in the HL gene. 26 refs., 4 figs., 2 tabs.

  7. FEMA DFIRM Hydraulic Structures

    Data.gov (United States)

    Minnesota Department of Natural Resources — This layer and accompanying attribute table is required whenever hydraulic structures are shown in the flood profile. It is also required if levees are shown on the...

  8. Constant-Pressure Hydraulic Pump

    Science.gov (United States)

    Galloway, C. W.

    1982-01-01

    Constant output pressure in gas-driven hydraulic pump would be assured in new design for gas-to-hydraulic power converter. With a force-multiplying ring attached to gas piston, expanding gas would apply constant force on hydraulic piston even though gas pressure drops. As a result, pressure of hydraulic fluid remains steady, and power output of the pump does not vary.

  9. Abdominal lift for laparoscopic cholecystectomy.

    Science.gov (United States)

    Gurusamy, Kurinchi Selvan; Koti, Rahul; Davidson, Brian R

    2013-08-31

    Laparoscopic cholecystectomy (key-hole removal of the gallbladder) is now the most often used method for treatment of symptomatic gallstones. Several cardiopulmonary changes (decreased cardiac output, pulmonary compliance, and increased peak airway pressure) occur during pneumoperitoneum, which is now introduced to allow laparoscopic cholecystectomy. These cardiopulmonary changes may not be tolerated in individuals with poor cardiopulmonary reserve. To assess the benefits and harms of abdominal wall lift compared to pneumoperitoneum in patients undergoing laparoscopic cholecystectomy. We searched the Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded until February 2013. We included all randomised clinical trials comparing abdominal wall lift (with or without pneumoperitoneum) versus pneumoperitoneum. We calculated the risk ratio (RR), rate ratio (RaR), or mean difference (MD) with 95% confidence intervals (CI) based on intention-to-treat analysis with both the fixed-effect and the random-effects models using the Review Manager (RevMan) software. For abdominal wall lift with pneumoperitoneum versus pneumoperitoneum, a total of 130 participants (all with low anaesthetic risk) scheduled for elective laparoscopic cholecystectomy were randomised in five trials to abdominal wall lift with pneumoperitoneum (n = 53) versus pneumoperitoneum only (n = 52). One trial which included 25 people did not state the number of participants in each group. All five trials had a high risk of bias. There was no mortality or conversion to open cholecystectomy in any of the participants in the trials that reported these outcomes. There was no significant difference in the rate of serious adverse events between the two groups (two trials; 2/29 events (0.069 events per person) versus 2/29 events (0.069 events per person); rate ratio 1.00; 95% CI 0

  10. ARSENIC TRIOXIDE DOWNREGULATES TELOMERASE ACTIVITY IN HL-60 CELLS

    Institute of Scientific and Technical Information of China (English)

    何冬梅; 张洹

    2002-01-01

    Objective: To evaluate whether arsenic trioxide (AS2O3) could downregulate human telomerase reverse transcriptase (hTERT) gene expression and telomerase activity during induction of apoptosis of HL-60 cells. Methods: Apoptosis was detected by morphological observation and flow cytomertric cell cycle analysis. The expression of hTERT at mRNA and protein levels was analyzed by reverse transcriptase polymerase chain reaction (RT-PCR) and immunofluorescence using fluoresce isothiocyanate (FITC) label, respectively. Telomerase activity was determined by polymerase chain reaction enzyme-linked immunoassay (PCR-ELISA). Results: Treatment of 2 μmol/L at As2O3 could induce apoptosis of HL-60 cells. hTERT was decreased at both mRNA and protein levels during apoptosis of HL-60 cells. Telomerase activity of HL-60 cells was significantly inhibited. Conclusion:It is suggested that telomerase activity of HL-60 cells might be specifically inhibited by AS2O3 through the downregulation of hTERT gene expression.

  11. Fast crab cavity failures in HL-LHC

    CERN Document Server

    Yee-Rendon, B; Calaga, R; Tomas, R; Zimmermann, F; Barranco, J

    2014-01-01

    Crab cavities (CCs) are a key ingredient of the High-Luminosity Large Hadron Collider (HL-LHC) to ensure head on collisions at the main experiments (ATLAS and CMS) and fully profit from the smaller provided by the ATS optics [1]. At KEKB, CCs have exhibited abrupt changes of phase and voltage during a time period of few LHC turns and considering the large energy stored in the HL-LHC beam, CC failures represent a serious risk to the LHC machine protection. In this paper, we discuss the effect of CC voltage or phase changes on a time interval similar to, or longer than, the one needed to dump the beam. The simulations assume a realistic steady-state distribution to assess the beam losses for the HL-LHC. Additionally, some strategies are studied in order to reduce the damage caused by the CC failures.

  12. HL7 with CORBA and OLE: software components for healthcare.

    Science.gov (United States)

    Rishel, W

    1996-01-01

    Componentized software promises easier, more fine-grained integration of disparate software systems. Variations of the technology can help to achieve tight coupling among disparate programs on the clinical workstation or across wide area networks. HL7 members have been designing extensions to the protocol for the exchange of healthcare information using Microsoft OLE and CORBA technologies. Extensive prototyping has been performed, including the simultaneous interconnection of sixteen different vendor systems exchanging demographic data and lab results. The first release of this standard will be notable in that the specifications for OLE and CORBA will be entirely isomorphic, they will be based directly, on HL7 version 2.3, and they may easily be implemented in systems that are not written using object-oriented programming tools. As HL7 version 3 is developed on an object-oriented model of healthcare information, the same approach will be used so information about the objects may be shared using CORBA and OLE.

  13. First Neutron Spectrometry Measurement at the HL-2A Tokamak

    CERN Document Server

    Xi, Yuan; Xufei, Xie; Zhongjing, Chen; Xingyu, Peng; Tieshuan, Fan; Jinxiang, Chen; Xiangqing, Li; Guoliang, Yuan; Jinwei, Yang; Qingwei, Yang

    2013-01-01

    A compact neutron spectrometer based on the liquid scintillator is presented for the neutron energy spectrum measurement at the HL-2A tokamak. The spectrometer has been well characterized and a fast digital pulse shape discrimination software has been developed using the charge comparison method. A digitizer data acquisition system with the maximum frequency of 1 MHz can work under the high count rate environment at HL-2A. Specific radiation shielding and magnetic shielding for the spectrometerhas been designed for the neutron spectrum measurement at the HL-2A Tokamak. For the analysis of the pulse height spectrum, dedicated numerical simulation utilizing NUBEAM combining with GENESIS has been made to obtain the neutron energy spectrum, following which the transportation process from the plasma to the detector has been evaluated with Monte Carlo calculations. The distorted neutron energy spectrum has been folded with response matrix of the liquid scintillation spectrometer, and good consistency has been found...

  14. Physics Prospects at the HL-LHC with ATLAS

    CERN Document Server

    Duncan, Anna Kathryn; The ATLAS collaboration

    2017-01-01

    The High-Luminosity LHC aims to provide a total integrated luminosity of 3000 fb-1 from p-p collisions at $\\sqrt{s}$ = 14 TeV over the course of $\\sim$ 10 years, reaching instantaneous luminosities of up to L = 7.5 $\\times$ 1034cm$^{-2}$s$^{-1}$, corresponding to an average ($\\mu$) of 200 inelastic p-p collisions per bunch crossing. The upgraded ATLAS detector must be able to cope well with increased occupancies and data rates. The performance of the upgrade has been estimated in full simulation studies, assuming expected HL-LHC conditions and a detector configuration intended to maximise physics performance and discovery potential at the HL-LHC. The performance is expected to be similar to what we have now. Simulation studies have been carried out to evaluate the prospects of various benchmark physics analyses to be performed using the upgraded ATLAS detector with the full HL-LHC dataset.

  15. EPICS在HL-2A控制系统PLC上的部署%EPICS deployment on the PLC of control system for HL-2A

    Institute of Scientific and Technical Information of China (English)

    王川; 夏凡; 潘莉; 潘卫; 赵丽; 宋啸; 李欣怡; 陈燎原

    2013-01-01

    为了提高HL-2A装置的实验数据交换效率,通过在HL-2A上部署EPICS系统,结合HL-2A的控制系统PLC,提出并建立了一种可行的HL-2A指令与数据共享方法,同时给出了程序的实例.%In order to improve the efficiency of HL-2A tokamak experimental data exchange,EPICS system has been deployed on the HL-2A and combined with the PLC of control system.A viable method for sharing HL-2A's instructions and data is established.At the end the instance of the program is given.

  16. Lift enhancement by trapped vortex

    Science.gov (United States)

    Rossow, Vernon J.

    1992-01-01

    The viewgraphs and discussion of lift enhancement by trapped vortex are provided. Efforts are continuously being made to find simple ways to convert wings of aircraft from an efficient cruise configuration to one that develops the high lift needed during landing and takeoff. The high-lift configurations studied here consist of conventional airfoils with a trapped vortex over the upper surface. The vortex is trapped by one or two vertical fences that serve as barriers to the oncoming stream and as reflection planes for the vortex and the sink that form a separation bubble on top of the airfoil. Since the full three-dimensional unsteady flow problem over the wing of an aircraft is so complicated that it is hard to get an understanding of the principles that govern the vortex trapping process, the analysis is restricted here to the flow field illustrated in the first slide. It is assumed that the flow field between the two end plates approximates a streamwise strip of the flow over a wing. The flow between the endplates and about the airfoil consists of a spanwise vortex located between the suction orifices in the endplates. The spanwise fence or spoiler located near the nose of the airfoil serves to form a separated flow region and a shear layer. The vorticity in the shear layer is concentrated into the vortex by withdrawal of fluid at the suction orifices. As the strength of the vortex increases with time, it eventually dominates the flow in the separated region so that a shear or vertical layer is no longer shed from the tip of the fence. At that point, the vortex strength is fixed and its location is such that all of the velocity contributions at its center sum to zero thereby making it an equilibrium point for the vortex. The results of a theoretical analysis of such an idealized flow field are described.

  17. 3D sensors for the HL-LHC

    CERN Document Server

    INSPIRE-00567197; Cavallaro, E.; Förster, F.; Grinstein, S.; Lange, J.; López Paz, I.; Manna, M.; Pellegrini, G.; Quirion, D.; Terzo, S.

    2016-01-01

    In order to increase its discovery potential, the Large Hadron Collider (LHC) accelerator will be upgraded in the next decade. The high luminosity LHC (HL-LHC) period demands new sensor technologies to cope with increasing radiation fluences and particle rates. The ATLAS experiment will replace the entire inner tracking detector with a completely new silicon-only system. 3D pixel sensors are promising candidates for the innermost layers of the Pixel detector due to their excellent radiation hardness at low operation voltages and low power dissipation at moderate temperatures. Recent developments of 3D sensors for the HL-LHC are presented.

  18. A New Criterion for Disruption Prediction on HL-2A

    Institute of Scientific and Technical Information of China (English)

    YANG Qing-Wei; JI Xiao-Quan; DING Xuan-Tong; HL-2A team; ZHOU Hang-Yu; FENG Bei-Bin; LIU Yi; PAN Yu-Dong; LI Wei; DUAN Xu-Ru; CHEN Wei; CUI Zheng-Ying

    2006-01-01

    @@ A new criterion has been proposed to predict the major disruptions caused by tearing mode instabilities. According to the HL-2A experimental results, the statistical analyses are employed to investigate the relationships between MHD activities and the plasma disruptions. Two kinds of the tearing mode activities can finally cause the disruption on HL-2A operations. By introducing a new parameter, i.e. an integral of poloidal magnetic field over time, as the criterion of disruption precursor, almost all of the disruptions can be predicted.

  19. Von Hippel-Lindau disease (vHL)

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Bisgaard, Søs Marie Luise; Harbud, Vibeke

    2013-01-01

    cell carcinoma), the adrenal glands (pheochromocytoma), the pancreas, as well as in other organs. As many different organs can be affected, several medical specialities often take part in both diagnosis and treatment of manifestations. vHL should be suspected in individuals with a family history...... of the disease, and/or in individuals with a vHL-associated manifestation; i.e. a hemangioblastoma in the retina or the central nervous system, familial or bilateral pheochromocytomas, familial, multiple, or early onset renal cell carcinomas, and in individuals with an endolymphatic sac tumour in the inner ear...

  20. HL-2A Tokamak Edge Modeling with B2

    Institute of Scientific and Technical Information of China (English)

    Pan Yudong(潘宇东); Wang Enyao(王恩耀); Liu Yi(刘仪)

    2003-01-01

    The outer divertor plasma of HL-2A and its associated scrape-off plasma have been simulated using a two-dimensional multi-species fluid code of Braams with a simplified neutral gas model. HL-2A has a double-null closed divertor in separate divertor chambers above and below the nearly circular plasma tours. The computed numerical grid is developed according to an ideal magnetic surface. The calculation is involved only with pure hydrogen plasma. The emphasis has been focused on parametric studies involving variation of the assumptions made for the core plasma. The peak temperatures and the heat flux near the target are of the principal concern.

  1. 3D sensors for the HL-LHC

    Science.gov (United States)

    Vázquez Furelos, D.; Carulla, M.; Cavallaro, E.; Förster, F.; Grinstein, S.; Lange, J.; López Paz, I.; Manna, M.; Pellegrini, G.; Quirion, D.; Terzo, S.

    2017-01-01

    In order to increase its discovery potential, the Large Hadron Collider (LHC) accelerator will be upgraded in the next decade. The high luminosity LHC (HL-LHC) period requires new sensor technologies to cope with increasing radiation fluences and particle rates. The ATLAS experiment will replace the entire inner tracking detector with a completely new silicon-only system. 3D pixel sensors are promising candidates for the innermost layers of the Pixel detector due to their excellent radiation hardness at low operation voltages and low power dissipation at moderate temperatures. Recent developments of 3D sensors for the HL-LHC are presented.

  2. Krajewski diagrams and spin lifts

    CERN Document Server

    Schücker, T

    2005-01-01

    A classification of irreducible, dynamically non-degenerate, almost commutative spectral triples is refined. It is extended to include centrally extended spin lifts. Simultaneously it is reduced by imposing three constraints: (i) the condition of vanishing Yang-Mills and mixed gravitational anomalies, (ii) the condition that the fermion representation be complex under the little group, while (iii) massless fermions are to remain neutral under the little group. These constraints single out the standard model with one generation of leptons and quarks and with an arbitrary number of colours.

  3. Training for lifting; an unresolved ergonomic issue?

    Science.gov (United States)

    Sedgwick, A W; Gormley, J T

    1998-10-01

    The paper describes a nine year project on lifting training which included nine trans-Australia consensus conferences attended by more than 900 health professionals. Major outcomes were: (1) The essence of lifting work is the need for the performer to cope with variability in task, environment, and self, and the essence of lifting skill is therefore adaptability; (2) the semi-squat approach provides the safest and most effective basis for lifting training; (3) for lifting training to be effective, the basic principles of skill learning must be systematically applied, with adaptability as a specific goal; (4) physical work capacity (aerobic power, strength, endurance, joint mobility) is a decisive ingredient of safe and effective lifting and, in addition to skill learning, should be incorporated in the training of people engaging regularly in heavy manual work; (5) if effective compliance with recommended skilled behaviour is to be achieved, then training must apply the principles and methods appropriate to adult learning and behaviour modification.

  4. Trend of hydraulic units

    Energy Technology Data Exchange (ETDEWEB)

    Deshimaru, Jun' ichi

    1988-11-01

    The gear, vane and piston pumps occupy a more then 90% share in the hydraulic pumps. Comparatively large pumps are mainly variable delivery piston pumps. The piston pumps are comparatively high in output density (output per unit weight), indicating the hydraulic pump in performance, and tend to become higher and higher in it. Though they are mainly 210 to 350kgf/cm/sup 2/ in rated pressure, some of them come to surpass 400kgf/cm/sup 3/ in it. While the progress in computation also requires the high speed operation, high accuracy and other severe conditions for the hydraulic units, which accordingly and increasingly intensify the requirement for hydraulic oil in abrasion resistibility, oxidation stability and response characteristics. While cavitation comes to easily occur, which considerably and disadvantageously influences hydraulic oil in life through degradation, noise level and respondingness. From now on, the development of high performance oil and study of mechanical structure are important. 19 references, 9 figures, 2 tables.

  5. Constraint Processing in Lifted Probabilistic Inference

    CERN Document Server

    Kisynski, Jacek

    2012-01-01

    First-order probabilistic models combine representational power of first-order logic with graphical models. There is an ongoing effort to design lifted inference algorithms for first-order probabilistic models. We analyze lifted inference from the perspective of constraint processing and, through this viewpoint, we analyze and compare existing approaches and expose their advantages and limitations. Our theoretical results show that the wrong choice of constraint processing method can lead to exponential increase in computational complexity. Our empirical tests confirm the importance of constraint processing in lifted inference. This is the first theoretical and empirical study of constraint processing in lifted inference.

  6. Fuel Cell Powered Lift Truck

    Energy Technology Data Exchange (ETDEWEB)

    Moulden, Steve [Sysco Food Service, Houston, TX (United States)

    2015-08-20

    This project, entitled “Recovery Act: Fuel Cell-Powered Lift Truck Sysco (Houston) Fleet Deployment”, was in response to DOE funding opportunity announcement DE-PS36-08GO98009, Topic 7B, which promotes the deployment of fuel cell powered material handling equipment in large, multi-shift distribution centers. This project promoted large-volume commercialdeployments and helped to create a market pull for material handling equipment (MHE) powered fuel cell systems. Specific outcomes and benefits involved the proliferation of fuel cell systems in 5-to 20-kW lift trucks at a high-profile, real-world site that demonstrated the benefits of fuel cell technology and served as a focal point for other nascent customers. The project allowed for the creation of expertise in providing service and support for MHE fuel cell powered systems, growth of existing product manufacturing expertise, and promoted existing fuel cell system and component companies. The project also stimulated other MHE fleet conversions helping to speed the adoption of fuel cell systems and hydrogen fueling technology. This document also contains the lessons learned during the project in order to communicate the successes and difficulties experienced, which could potentially assist others planning similar projects.

  7. Yoshida lifts and Selmer groups

    CERN Document Server

    Böcherer, Siegfried; Schulze-Pillot, Rainer

    2010-01-01

    Let $f$ and $g$, of weights $k'>k\\geq 2$, be normalised newforms for $\\Gamma_0(N)$, for square-free $N>1$, such that, for each Atkin-Lehner involution, the eigenvalues of $f$ and $g$ are equal. Let $\\lambda\\mid\\ell$ be a large prime divisor of the algebraic part of the near-central critical value $L(f\\otimes g,\\frac{k+k'-2}{2})$. Under certain hypotheses, we prove that $\\lambda$ is the modulus of a congruence between the Hecke eigenvalues of a genus-two Yoshida lift of (Jacquet-Langlands correspondents of) $f$ and $g$ (vector-valued in general), and a non-endoscopic genus-two cusp form. In pursuit of this we also give a precise pullback formula for a genus-four Eisenstein series, and a general formula for the Petersson norm of a Yoshida lift. Given such a congruence, using the $4$-dimensional $\\lambda$-adic Galois representation attached to a genus-two cusp form, we produce, in an appropriate Selmer group, an element of order $\\lambda$, as required by the Bloch-Kato conjecture on values of $L$-functions. (Her...

  8. Cavitation in Hydraulic Machinery

    Energy Technology Data Exchange (ETDEWEB)

    Kjeldsen, M.

    1996-11-01

    The main purpose of this doctoral thesis on cavitation in hydraulic machinery is to change focus towards the coupling of non-stationary flow phenomena and cavitation. It is argued that, in addition to turbulence, superimposed sound pressure fluctuations can have a major impact on cavitation and lead to particularly severe erosion. For the design of hydraulic devices this finding may indicate how to further limit the cavitation problems. Chapter 1 reviews cavitation in general in the context of hydraulic machinery, emphasizing the initial cavitation event and the role of the water quality. Chapter 2 discusses the existence of pressure fluctuations for situations common in such machinery. Chapter 3 on cavitation dynamics presents an algorithm for calculating the nucleation of a cavity cluster. Chapter 4 describes the equipment used in this work. 53 refs., 55 figs.,10 tabs.

  9. Hybrid Airships for Lift: A New Lift Paradigm and a Pragmatic Assessment of the Vehicle’s Key Operational Challenges

    Science.gov (United States)

    2011-12-01

    required lift for flight, Hybrid Airships use a combination of buoyant lift (provided by a gas such as Helium), aerodynamic lift (generated by airflow...AIR FORCE FELLOWS AIR UNIVERSITY HYBRID AIRSHIPS FOR LIFT: A NEW LIFT PARADIGM AND A PRAGMATIC ASSESSMENT OF THE...00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE Hybrid Airships for Lift: A New Lift Paradigm And A Pragmatic Assessment Of The Vehicle’s Key

  10. Hydraulics and pneumatics

    CERN Document Server

    Parr, Andrew

    2006-01-01

    Nearly all industrial processes require objects to be moved, manipulated or subjected to some sort of force. This is frequently accomplished by means of electrical equipment (such as motors or solenoids), or via devices driven by air (pneumatics) or liquids (hydraulics).This book has been written by a process control engineer as a guide to the operation of hydraulic and pneumatic systems for all engineers and technicians who wish to have an insight into the components and operation of such a system.This second edition has been fully updated to include all recent developments su

  11. Popeye Project: Hydraulic umbilical

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, K.G.; Williams, V.T.

    1996-12-31

    For the Popeye Project, the longest super-duplex hydraulic umbilical in the world was installed in the Gulf of Mexico. This paper reports on its selection and project implementation. Material selection addresses corrosion in seawater, water-based hydraulic fluid, and methanol. Five alternatives were considered: (1) carbon-steel with traditional coating and anodes, (2) carbon-steel coated with thermally sprayed aluminum, (3) carbon-steel sheathed in aluminum, (4) super-duplex, and (5) titanium. The merits and risks associated with each alternative are discussed. The manufacture and installation of the selected umbilical are also reported.

  12. Towards Optimum Material Choices for HL-LHC Collimator Upgrade

    CERN Document Server

    Quaranta, E.; Biancacci, N.; Bruce, R.; Carra, F.; Métral, E.; Redaelli, S.; Rossi, A.; Salvant, B.

    2016-01-01

    properties that address different limitations of the present collimation system, solutions have been found to fulfil various upgrade challenges. This paper describes the proposed staged approach to deploy new materials in the upgraded HL-LHC collimation system. Beam tests at the CERN HiRadMat facility were also performed to benchmark simulation methods and constitutive material models.

  13. Snake Studies in the HL-1M Tokamak

    Institute of Scientific and Technical Information of China (English)

    LIUYi; GUOGancheng; ZHONGYunze; FUBinzhong; DONGJiafu

    2002-01-01

    Lower-hybrid current drive (LHCD) experiments were carried out the HL-1M hydrogen plasmas. The effect of LHCD on central MHD activities [sawtooth (m=0), m =1 mode] were studied with the fluctuations observation of the soft X-ray (SXR) emission.

  14. Connecting HL Tau to the observed exoplanet sample

    Science.gov (United States)

    Simbulan, Christopher; Tamayo, Daniel; Petrovich, Cristobal; Rein, Hanno; Murray, Norman

    2017-08-01

    The Atacama Large Millimeter/submilimeter Array (ALMA) recently revealed a set of nearly concentric gaps in the protoplanetary disc surrounding the young star HL Tauri (HL Tau). If these are carved by forming gas giants, this provides the first set of orbital initial conditions for planets as they emerge from their birth discs. Using N-body integrations, we have followed the evolution of the system for 5 Gyr to explore the possible outcomes. We find that HL Tau initial conditions scaled down to the size of typically observed exoplanet orbits naturally produce several populations in the observed exoplanet sample. First, for a plausible range of planetary masses, we can match the observed eccentricity distribution of dynamically excited radial velocity giant planets with eccentricities >0.2. Secondly, we roughly obtain the observed rate of hot Jupiters around FGK stars. Finally, we obtain a large efficiency of planetary ejections of ≈2 per HL Tau-like system, but the small fraction of stars observed to host giant planets makes it hard to match the rate of free-floating planets inferred from microlensing observations. In view of upcoming Gaia results, we also provide predictions for the expected mutual inclination distribution, which is significantly broader than the absolute inclination distributions typically considered by previous studies.

  15. Pellet Enhanced Performance on the HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    DING Xuan-Tong; LIU Yi; ZHOU Yan; PAN Yu-Dong; CUI Zheng-Ying; HUANG Yuan; LIU Ze-Tian; SHI Zhong-Bing; JI Xiao-Quan; XIAO Wei-Wen; LIU Yong; YANG Qing-Wei; YAN Long-Wen; ZHU Gen-Liang; XIAO Zheng-Gui; LIU De-Quan; CAO Zeng; GAO Qing-Di; LONG Yong-Xing

    2006-01-01

    @@ Enhanced confinement has been achieved by the centre fuelling of pellet injection on the HL-2A tokamak. The energy confinement time increases from 50ms to 140ms after the pellet injection. Experimental results show that the improvement of the confinement is related to the decrease of the electron heat transport.

  16. Deconvolution methods based on φHL regularization for spectral recovery.

    Science.gov (United States)

    Zhu, Hu; Deng, Lizhen; Bai, Xiaodong; Li, Meng; Cheng, Zhao

    2015-05-10

    The recorded spectra often suffer noise and band overlapping, and deconvolution methods are always used for spectral recovery. However, during the process of spectral recovery, the details cannot always be preserved. To solve this problem, two regularization terms are introduced and proposed. First, the conditions on the regularization term are analyzed for smoothing noise and preserving detail, and according to these conditions, φHL regularization is introduced into the spectral deconvolution model. In view of the deficiency of φHL under noisy condition, adaptive φHL regularization (φAHL) is proposed. Then semi-blind deconvolution methods based on φHL regularization (SBD-HL) and based on adaptive φHL regularization (SBD-AHL) are proposed, respectively. The simulation experimental results indicate that the proposed SBD-HL and SBD-AHL methods have better recovery, and SBD-AHL is superior to SBD-HL, especially in the noisy case.

  17. Hydraulic Arm Modeling via Matlab SimHydraulics

    OpenAIRE

    Věchet, Stanislav; Krejsa, Jiří

    2009-01-01

    System modeling is a vital tool for cost reduction and design process speed up in most engineering fields. The paper is focused on modeling of hydraulic arm as a part of intelligent prosthesis project, in the form of 2DOF open kinematic chain. The arm model combines mechanical, hydraulic and electric subsystems and uses Matlab as modeling tool. SimMechanics Matlab extension is used for mechanical part modeling, SimHydraulics toolbox is used for modeling of hydraulic circuit used for actuating...

  18. Isolated neck-lifting procedure: isolated stork lift.

    Science.gov (United States)

    Barbarino, Sheila C; Wu, Allan Y; Morrow, David M

    2013-04-01

    Many patients desire cosmetic improvement of neck laxity when consulting with a plastic surgeon about their face. Neck laxity and loss of the cervicomental angle can be due to multiple components of aging such as skin quality/elasticity, loss of platysma muscle tone, and submental fat accumulation. Traditionally, the procedure of choice for patients with an aging lower face and neck is a cervicofacial rhytidectomy. However, occasionally, a patient wishes to have no other facial surgery than an improvement of their excessive skin of the anterior, lateral, and/or posterior neck. In other instances, a patient may present with having had a face/neck-lifting procedure that left objectionable vertical/diagonal lines at the lateral neck. In both these instances, a surgeon should consider an isolated stork lift (ISL) procedure. An ISL procedure avoids and/or corrects problematic vertical/diagonal lateral neck folds by "walking" the excess skin flaps around the posterior inferior occipital hairline bilaterally, bringing the flaps together at the lateral and posterior neck, which sometimes involves a midline posterior dart excision of the dog ear. A patient presenting with excessive skin of the neck (anterior, lateral, and/or posterior) and/or residual vertical/diagonal skin folds is an excellent candidate for the ISL. The ISL procedure was performed on 273 patients over a 2-year period at The Morrow Institute. Patients were included if they had excessive skin of the anterior, lateral, and/or posterior neck and/or diagonal/vertical lateral bands and did not desire a full face-lifting procedure. Patients were excluded from this study if they would not accept having longer hair in order to cover the scar along the posterior inferior occipital hairline or a midline T-flap skin closure scar at the base of the posterior midline neck. Under a combination of local anesthesia and IV sedation, a postauricular face-lift incision was made that was extended in a circumoccipital fashion

  19. 33 CFR 118.85 - Lights on vertical lift bridges.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lights on vertical lift bridges... BRIDGES BRIDGE LIGHTING AND OTHER SIGNALS § 118.85 Lights on vertical lift bridges. (a) Lift span lights. The vertical lift span of every vertical lift bridge shall be lighted so that the center of the...

  20. Impact of mitochondria on nitrite metabolism in HL-1 cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Peter eDungel

    2013-05-01

    Full Text Available Apart from ATP synthesis mitochondria have many other functions, one being nitrite reductase activity. NO released from nitrite has been shown to protect the heart from ischemia/reperfusion injury in a cGMP-dependent manner. However, the exact impact of mitochondria on the release of NO from nitrite in cardiomyocytes is not completely understood. Besides mitochondria, a number of non-mitochondrial metalloproteins have been suggested to facilitate this process. The aim of this study was to investigate the impact of mitochondria on the bioactivation of nitrite in HL-1 cardiomyocytes.The levels of nitrosyl complexes of hemoglobin (NO-Hb and cGMP levels were measured by electron spin resonance spectroscopy and enzyme immunoassay. In addition the formation of free NO was determined by confocal microscopy as well as intracellular nitrite and S-nitrosothiols by chemoluminescence analysis. NO was released from nitrite in cell culture in an oxygen dependent manner. Application of specific inhibitors of the respiratory chain, p450, NO synthases and xanthine oxidoreductase showed that all four enzymatic systems are involved in the release of NO, but more than 50% of NO is released via the mitochondrial pathway. Only NO released by mitochondria activated cGMP synthesis. Cardiomyocytes co-cultured with red blood cells (RBC competed with RBC for nitrite, but free NO was detected only in HL-1 cells suggesting that RBC are not a source of NO in this model. Apart from activation of cGMP synthesis, NO formed in HL-1 cells diffused out of the cells and formed NO-Hb complexes. In addition nitrite was converted by HL-1 cells to S-nitrosyl complexes. In HL-1 cardiomyocytes, several enzymatic systems are involved in nitrite reduction to NO but only the mitochondrial pathway of NO release activates cGMP synthesis. Our data suggest that this pathway may be a key regulator of myocardial contractility especially under hypoxic conditions.

  1. HYDRAULICS, TUSCARAWAS COUNTY, OHIO, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulic data include spatial datasets and data tables necessary for documenting the hydraulic procedures for estimating flood discharges for a flood insurance...

  2. Modelling of Hydraulic Robot

    DEFF Research Database (Denmark)

    Madsen, Henrik; Zhou, Jianjun; Hansen, Lars Henrik

    1997-01-01

    This paper describes a case study of identifying the physical model (or the grey box model) of a hydraulic test robot. The obtained model is intended to provide a basis for model-based control of the robot. The physical model is formulated in continuous time and is derived by application...

  3. Water Treatment Technology - Hydraulics.

    Science.gov (United States)

    Ross-Harrington, Melinda; Kincaid, G. David

    One of twelve water treatment technology units, this student manual on hydraulics provides instructional materials for three competencies. (The twelve units are designed for a continuing education training course for public water supply operators.) The competencies focus on the following areas: head loss in pipes in series, function loss in…

  4. CNOOC Lifts 2011 Production Target

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ China National Offshore Oil Corporation (CNOOC), China's top offshore oil and gas producer, has lifted its 2011 production target by up to 11 percent as new projects at home and overseas come on stream.The offshore oil giant, with a market capitalization of about US$105 billion, said in a statement released in late January 2011 that it aimed to produce between 355 and 365 million barrels of oil equivalent (BOE).Oil prices climbed 15 percent in 2010 on the back of expectations that a global economic recovery will drive the demand.Analysts are similarly bullish for 2011, predicting crude prices to trade at around US$100 for the year.CNOOC, the smallest of China's triumvirate of energy companies that also includes CNPC and Sinopee, said it targeted US$8.8 billion in capital expenditure for 2011.

  5. Heavy-lift airship dynamics

    Science.gov (United States)

    Tischler, M. B.; Ringland, R. F.; Jex, H. R.

    1983-01-01

    The basic aerodynamic and dynamic properties of an example heavy-lift airship (HLA) configuration are analyzed using a nonlinear, multibody, 6-degrees-of-freedom digital simulation. The slung-payload model is described, and a preliminary analysis of the coupled vehicle-payload dynamics is presented. Trim calculations show the importance of control mixing selection and suggest performance deficiencies in crosswind stationkeeping for the unloaded example HLA. Numerically linearized dynamics of the unloaded vehicle exhibit a divergent yaw mode and an oscillatory pitch mode whose stability characteristic is sensitive to flight speed. An analysis of the vehicle-payload dynamics shows significant coupling of the payload dynamics with those of the basic HLA. It is shown that significant improvement in the vehicle's dynamic behavior can be achieved with the incorporation of a simple flight controller having proportional, rate, and integral-error feedbacks.

  6. Lip Lifting: Unveiling Dental Beauty.

    Science.gov (United States)

    Stanley, Kyle; Caligiuri, Matthew; Schlichting, Luís Henrique; Bazos, Panaghiotis K; Magne, Michel

    2017-01-01

    The focus for the achievement of complete success in the esthetic zone has traditionally been on addressing deficiencies of intraoral hard and soft tissue. Often, these deficiencies are accompanied by esthetic concerns regarding the lips that are routinely neglected by the dental team. A predictable plastic surgery technique - the lip lift - has been used for decades to enhance lip esthetics by shortening the senile upper lip to achieve a more youthful appearance. Over the years, this technique has been refined and used in many different ways, allowing its routine incorporation into full facial esthetic planning. Through restoration of the upper lip to its optimal position, the artistry of the dentist and dental technician can truly be appreciated in the rejuvenated smile. By the introduction of this minimally invasive surgical technique to the dental community, patients stand to benefit from a comprehensive orofacial approach to anterior dental esthetic planning.

  7. How to Lift a Heavy Object?

    Institute of Scientific and Technical Information of China (English)

    丁凤丽

    2007-01-01

    <正>Many people hurt their backs when they try to lift heavy things from the floor. It is easy to hurt your back muscles when you pick up a heavy object. However, there is a correct way to lift things from the floor. If you pick up big or heavy objects correctly, you probably will not hurt your back.

  8. Improving Grading Consistency through Grade Lift Reporting

    Science.gov (United States)

    Millet, Ido

    2010-01-01

    We define Grade Lift as the difference between average class grade and average cumulative class GPA. This metric provides an assessment of how lenient the grading was for a given course. In 2006, we started providing faculty members individualized Grade Lift reports reflecting their position relative to an anonymously plotted school-wide…

  9. Soccer Ball Lift Coefficients via Trajectory Analysis

    Science.gov (United States)

    Goff, John Eric; Carre, Matt J.

    2010-01-01

    We performed experiments in which a soccer ball was launched from a machine while two high-speed cameras recorded portions of the trajectory. Using the trajectory data and published drag coefficients, we extracted lift coefficients for a soccer ball. We determined lift coefficients for a wide range of spin parameters, including several spin…

  10. Soccer Ball Lift Coefficients via Trajectory Analysis

    Science.gov (United States)

    Goff, John Eric; Carre, Matt J.

    2010-01-01

    We performed experiments in which a soccer ball was launched from a machine while two high-speed cameras recorded portions of the trajectory. Using the trajectory data and published drag coefficients, we extracted lift coefficients for a soccer ball. We determined lift coefficients for a wide range of spin parameters, including several spin…

  11. Occupational lifting and pelvic pain during pregnancy:

    DEFF Research Database (Denmark)

    Larsen, Pernille Stemann; Strandberg-Larsen, Katrine; Juhl, Mette;

    2013-01-01

    OBJECTIVES: Pelvic pain during pregnancy is a common ailment, and the disease is a major cause of sickness absence during pregnancy. It is plausible that occupational lifting may be a risk factor of pelvic pain during pregnancy, but no previous studies have examined this specific exposure. The aim...... of this study was to examine the association between occupational lifting and pelvic pain during pregnancy. METHODS: The study comprised 50 143 pregnant women, enrolled in the Danish National Birth Cohort in the period from 1996-2002. During pregnancy, the women provided information on occupational lifting...... (weight load and daily frequency), and six months post partum on pelvic pain. Adjusted odds ratios for pelvic pain during pregnancy according to occupational lifting were calculated by logistic regression. RESULTS: Any self-reported occupational lifting (>1 time/day and loads weighing >10 kg...

  12. Lift conference | 5-7 February

    CERN Multimedia

    2014-01-01

    Since 2006, Lift Events explore the business and social implications of new technologies through the organisation of international event series and open innovation programs in Europe, Asia and America. The next conference will be held on 5-7 February in Geneva.   (Image: © Lift Conference) The Lift Conference is one of the leading conferences on innovation in Europe and a key annual meeting for individuals and organizations wishing to understand and anticipate trends and innovation. Held every year in February in Geneva (5-7 February 2014), the Lift Conference is a three-day event consisting of talks, interactive workshops, exhibitions, and discussions bringing together over 1’000 participants from all society’s sectors and industries in a dynamic and informal environment with the aim to learn, connect, share and leverage innovation opportunities.   Extraordinary speakers will take to the stage at Lift14: Porter Erisman, former VP of Alibaba.com turned...

  13. Lambda-Lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, Olivier; Schultz, Ulrik Pagh

    2002-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda-lifting...... that yields the cubic factor in the traditional formulation of lambda-lifting, which is due to Johnsson. This search is carried out by computing a transitive closure. To reduce the complexity of lambda-lifting, we partition the call graph of the source program into strongly connected components, based...... of lambda-lifting from O(n^3) to O(n^2) . where n is the size of the program. Since a lambda-lifter can output programs of size O(n^2), our algorithm is asympotically optimal....

  14. Lambda-Lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, Olivier; Schultz, Ulrik Pagh

    2004-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda-lifting...... that yields the cubic factor in the traditional formulation of lambda-lifting, which is due to Johnsson. This search is carried out by computing a transitive closure. To reduce the complexity of lambda-lifting, we partition the call graph of the source program into strongly connected components, based...... of lambda-lifting from O(n^3) to O(n^2) . where n is the size of the program. Since a lambda-lifter can output programs of size O(n^2), our algorithm is asympotically optimal....

  15. Lambda-Lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, Olivier; Schultz, Ulrik Pagh

    2003-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda-lifting...... that yields the cubic factor in the traditional formulation of lambda-lifting, which is due to Johnsson. This search is carried out by computing a transitive closure. To reduce the complexity of lambda-lifting, we partition the call graph of the source program into strongly connected components, based...... of lambda-lifting from O(n^3) to O(n^2) . where n is the size of the program. Since a lambda-lifter can output programs of size O(n^2), our algorithm is asympotically optimal....

  16. Lambda-lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, O.; Schultz, U.P.

    2004-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda-lifting...... that yields the cubic factor in the traditional formulation of lambda-lifting, which is due to Johnsson. This search is carried out by computing a transitive closure. To reduce the complexity of lambda-lifting, we partition the call graph of the source program into strongly connected components, based...... of lambda-lifting from O(n^3) to O(n^2) . where n is the size of the program. Since a lambda-lifter can output programs of size O(n^2), our algorithm is asympotically optimal....

  17. Lifting index of the niosh lifting equation and low back pain

    Directory of Open Access Journals (Sweden)

    Eliana Remor Teixeira

    2011-09-01

    Full Text Available The purpose of this study is to assess the relationship of the Lifting Index obtained through the application of the NIOSH Lifting Equation and the incidence of low back pain among forty-eight workers involved in manual lifting tasks. It was applied the equation in eleven tasks and the workers were interviewed. The most unfavorable conditions presented themselves in the lifting destination. The variables that most contributed to the inadequate values of the Lifting Index were: the horizontal location, the lifting frequency and the vertical distance, beyond the high weight of the load. The incidence of low back pain in the last twelve months was 19%, whereas the incidence of work-related low back pain in the same period was 10%. In 72.7% of the tasks evaluated the Composite Lifting Index was more than three, which are considered as high ergonomic risk.

  18. Design and Construction of a Hydraulic Ram Pump

    Directory of Open Access Journals (Sweden)

    Shuaibu Ndache MOHAMMED

    2007-09-01

    Full Text Available The Design and Fabrication of a Hydraulic Ram Pump (Hydram is undertaken. It is meant to lift water from a depth of 2m below the surface with no other external energy source required. Based on the design the volume flow rate in the derived pipe was 4.5238 × 10-5 m3/s (2.7 l/min, Power was 1.273 kW which results in an efficiency of 57.3%. The overall cost of fabrication of this hydram shows that the pump is relatively cheaper than the existing pumps.

  19. Study on Knowledge -based Intelligent Fault Diagnosis of Hydraulic System

    Directory of Open Access Journals (Sweden)

    Xuexia Liu

    2012-12-01

    Full Text Available A general framework of hydraulic fault diagnosis system was studied. It consisted of equipment knowledge bases, real-time databases, fusion reasoning module, knowledge acquisition module and so on. A tree-structure model of fault knowledge was established. Fault nodes knowledge was encapsulated by object-oriented technique. Complete knowledge bases were made including fault bases and diagnosis bases. It could describe the fault positions, the structure of fault, cause-symptom relationships, diagnosis principles and other knowledge. Taking the fault of left and right lifting oil cylinder out of sync for example, the diagnostic results show that the methods were effective.

  20. Selections from 2016: Gaps in HL Tau's Protoplanetary Disk

    Science.gov (United States)

    Kohler, Susanna

    2016-12-01

    Editors note:In these last two weeks of 2016, well be looking at a few selections that we havent yet discussed on AAS Nova from among the most-downloaded paperspublished in AAS journals this year. The usual posting schedule will resume after the AAS winter meeting.Gas Gaps in the Protoplanetary Disk Around the Young Protostar HL TauPublished March 2016The dust (left) and gas (right) emission from HL Tau show that the gaps in its disk match up. [Yen et al. 2016]Main takeaway:At the end of last year, the Atacama Large Millimeter/Submillimeter Array released some of its first data including a spectacular observation of a dusty protoplanetary disk around the young star HL Tau. In this follow-up study, a team led by Hsi-Wei Yen (Academia Sinica Institute of Astronomy and Astrophysics, Taiwan) analyzed the ALMA data and confirmed the presence of two gaps in the gas of HL Taus disk, at radii of 28 and 69 AU.Why its interesting:The original ALMA image of HL Taus disk suggests the presence of gaps in disk, but scientists werent sure if they were caused by effects like gravitational instabilities or dust clumping, or if the gaps were created by the presence of young planets. Yen and collaborators showed that gaps in the disks gas line up with gaps in its dust, supporting the model in which these gaps have been carved out by newly formed planets.Added intrigue:The evidence for planets in this disk came as a bit of a surprise, since it was originally believed that it takes tens of millions of years to form planets from the dust of protoplanetary disks but HL Tau is only a million years old. These observations therefore suggest that planets start to form much earlier than we thought.CitationHsi-Wei Yen et al 2016 ApJL 820 L25. doi:10.3847/2041-8205/820/2/L25

  1. Occupational lifting of heavy loads and preterm birth:

    DEFF Research Database (Denmark)

    Runge, Stine Bjerrum; Pedersen, Jacob Krabbe; Svendsen, Susanne Wulff

    2013-01-01

    To examine the association between occupational lifting during pregnancy and preterm birth. The risk of preterm birth was estimated for total burden lifted per day and number of medium and heavy loads lifted per day.......To examine the association between occupational lifting during pregnancy and preterm birth. The risk of preterm birth was estimated for total burden lifted per day and number of medium and heavy loads lifted per day....

  2. Prevalence, birth incidence, and penetrance of von Hippel-Lindau disease (vHL) in Denmark

    DEFF Research Database (Denmark)

    Binderup, Marie Louise Mølgaard; Galanakis, Michael Carter Bisgaard; Budtz-Jørgensen, Esben

    2017-01-01

    . We further used national health registers to identify individuals who fulfilled the clinical diagnostic vHL criteria based on their registered diagnostic codes, but had not been diagnosed with vHL. We also assessed the medical histories of first-degree relatives to identify familial cases. This study...... gives the first national estimates of vHL prevalence (1 in 46 900 individuals) and birth incidence (1 in 27 300 live births). vHL has been underdiagnosed in Denmark, and as many as 25% of the overall vHL cohort (diagnosed+undiagnosed patients) have a missed diagnosis in spite of fulfilling...

  3. Hydraulic manipulator research at ORNL

    Energy Technology Data Exchange (ETDEWEB)

    Kress, R.L.; Jansen, J.F. [Oak Ridge National Lab., TN (United States); Love, L.J. [Oak Ridge Inst. for Science and Education, TN (United States)

    1997-03-01

    Recently, task requirements have dictated that manipulator payload capacity increase to accommodate greater payloads, greater manipulator length, and larger environmental interaction forces. General tasks such as waste storage tank cleanup and facility dismantlement and decommissioning require manipulator life capacities in the range of hundreds of pounds rather than tens of pounds. To meet the increased payload capacities demanded by present-day tasks, manipulator designers have turned once again to hydraulics as a means of actuation. In order to successfully design, build, and deploy a new hydraulic manipulator (or subsystem), sophisticated modeling, analysis, and control experiments are usually needed. Oak Ridge National Laboratory (ORNL) has a history of projects that incorporate hydraulics technology, including mobile robots, teleoperated manipulators, and full-scale construction equipment. In addition, to support the development and deployment of new hydraulic manipulators, ORNL has outfitted a significant experimental laboratory and has developed the software capability for research into hydraulic manipulators, hydraulic actuators, hydraulic systems, modeling of hydraulic systems, and hydraulic controls. The purpose of this article is to describe the past hydraulic manipulator developments and current hydraulic manipulator research capabilities at ORNL. Included are example experimental results from ORNL`s flexible/prismatic test stand.

  4. Development of predictive equations for lifting strengths.

    Science.gov (United States)

    Kumar, S

    1995-10-01

    The purpose of the study was to determine relationship between lifting strengths of male and female subjects and body posture, type of lift (stoop or squat) and velocity of lift. Thirty normal young adults (18 males and 12 females) volunteered for the study. All subjects were required to perform a total of 56 tasks. Of these, 28 were stoop lifts and 28 were squat lifts. In each of the categories of stoop and squat lifts, the strengths were tested in standard posture, isokinetic (linear velocity of 500 mm/s), and isometric modes at half, three-quarters and full horizontal individual reach distances in sagittal, 30 degrees lateral and 60 degrees lateral planes. The strengths were measured using a static dynamic strength tester with a load cell and an IBM microcomputer with an A/D card. The peak and average strength values were extracted and statistically compared across conditions and gender (ANOVA). Finally a multiple regression analysis was carried out to predict strength as a function of reach, posture and velocity of lift. The ANOVA revealed a highly significant effect of gender, reach, plane and velocity (p capabilities for industrial application based on simple anthropometric and strength characteristics.

  5. Systemic and Local Responses to Repeated HL Stress-Induced Retrograde Signaling in Arabidopsis.

    Science.gov (United States)

    Gordon, Matthew J; Carmody, Melanie; Albrecht, Verónica; Pogson, Barry

    2012-01-01

    CHLOROPLASTS OF LEAVES UNDER HIGH LIGHT STRESS INITIATE SIGNALS TO THE NUCLEI OF BOTH EXPOSED AND DISTAL LEAVES IN ORDER TO ACCLIMATE AGAINST THE POTENTIAL THREAT OF OXIDATIVE DAMAGE: a process known as high light systemic acquired acclimation (HL SAA). This study explores the nature of HL SAA, synergistic interactions with other environmental stresses, and the impact of repeated HL stress on the acclimation response of exposed and distal leaves. This necessitated the development of novel experimental systems to investigate the initiation, perception, and response to HL SAA. These systems were used to investigate the HL SAA response by monitoring the induction of mRNA in distal leaves not exposed to the HL stress. Acclimation to HL is induced within minutes and the response is proportionally dependent on the quality and quantity of light. HL SAA treatments in conjunction with variations in temperature and humidity reveal HL SAA is influenced by fluctuations in humidity. These treatments also result in changes in auxin accumulation and auxin-responsive genes. A key question in retrograde signaling is the extent to which transient changes in light intensity result in a "memory" of the event leading to acclimation responses. Repeated exposure to short term HL resulted in acclimation of the exposed tissue and that of emerging and young leaves (but not older leaves) to HL and oxidative stress.

  6. Upgrades of the CMS Outer Tracker for HL-LHC

    Science.gov (United States)

    Sguazzoni, Giacomo

    2017-02-01

    The LHC machine is planning an upgrade program which will smoothly bring the luminosity to about 5 ×1034cm-2s-1 around 2028, to possibly reach an integrated luminosity of 3000 fb-1 in the following decade. This High Luminosity LHC scenario, HL-LHC, will require a preparation program of the LHC detectors known as Phase-2 upgrade. The current CMS Outer Tracker, already running close to its design limits, will not be able to survive HL-LHC radiation conditions and CMS will need a completely new device, in order to fully exploit the highly demanding operating conditions and the delivered luminosity. The new Tracker should have also L1 trigger capabilities. To achieve such goals, R&D activities are ongoing to explore options and develop solutions that would allow including tracking information at Level-1. The design choices for the CMS Outer Tracker upgrades are discussed along with some highlights of the R&D activities.

  7. Identification of genes responsive to apoptosis in HL-60 cells

    Institute of Scientific and Technical Information of China (English)

    Wei JIN; Le-feng QU; Ping MIN; Shan CHEN; Hong LI; He LU; Yong-tai HOU

    2004-01-01

    AIM: To identify genes responsive to apoptosis in HL-60 cells treated by homoharringtonine. METHODS: cDNA microarray technology was used to detect gene expression and the result of microarrays for genes (TIEG and VDUP1) was confirmed by Northern analysis. RESULTS: Seventy-five individual mRNAs whose mass changed significantly were identified. Among these genes (25 were up-regulated and 50 were down-regulated), most are known related to oncogenes and tumor suppressor. Some genes were involved in apoptosis signaling pathways.CONCLUSION: TGFβ and TNF apoptosis signaling pathways were initiated during apoptosis in HL-60 cells.TIEG and VDUP1 play important roles in mediating apoptosis.

  8. The CMS HGCAL detector for HL-LHC upgrade

    CERN Document Server

    Martelli, Arabella

    2017-01-01

    The High Luminosity LHC (HL-LHC) will integrate 10 times more luminosity than the LHC, posing significant challenges for radiation tolerance and event pileup on detectors, especially for forward calorimetry, and hallmarks the issue for future colliders. As part of its HL-LHC upgrade program, the CMS collaboration is designing a High Granularity Calorimeter to replace the existing endcap calorimeters. It features unprecedented transverse and longitudinal segmentation for both electromagnetic (ECAL) and hadronic (HCAL) compartments. This will facilitate particle-flow calorimetry, where the fine structure of showers can be measured and used to enhance pileup rejection and particle identification, whilst still achieving good energy resolution. The ECAL and a large fraction of HCAL will be based on hexagonal silicon sensors of 0.5 - 1 cm$^2$ cell size, with the remainder of the HCAL based on highly-segmented scintillators with SiPM readout. The intrinsic high-precision timing capabilities of the silicon sensors wi...

  9. The ATLAS tracker Pixel detector for HL-LHC

    CERN Document Server

    Gemme, Claudia; The ATLAS collaboration

    2017-01-01

    The high luminosity upgrade of the LHC (HL-LHC) in 2026 will provide new challenges to the ATLAS tracker. The current Inner Detector will be replaced with a whole silicon tracker which will consist of a five barrel layer Pixel detector surrounded by a four barrel layer Strip detector. The expected high radiation levels are requiring the development of upgraded silicon sensors as well as new a front-end chip. The dense tracking environment will require finer granularity detectors. The data rates will require new technologies for high bandwidth data transmission and handling. The current status of the HL-LHC ATLAS Pixel detector developments as well as the various layout options are reviewed.

  10. Imaging System and Plasma Imaging on HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    郑银甲; 冯震; 罗萃文; 刘莉; 李伟; 严龙文; 杨青巍; 刘永

    2004-01-01

    As a new diagnostic means, plasma-imaging system has been developed on the HL2A tokamak, with a basic understanding of plasma discharge scenario of the entire torus, checking the plasma position and the clearance between the plasma and the first wall during discharge. The plasma imaging system consists of (1) color video camera, (2) observation window and turn mirror,(3) viewing & collecting optics, (4) video cable, (5) Video capture card as well as PC. This paper mainly describes the experimental arrangement, plasma imaging system and detailed part in the system, along with the experimental results. Real-time monitoring of plasma discharge process,particularly distinguishing limitor and divertor configuration, the imaging system has become key diagnostic means and laid the foundation for further physical experiment on the HL-2A tokamak.

  11. Physics potential of ATLAS upgrades at HL-LHC

    CERN Document Server

    Testa, Marianna; The ATLAS collaboration

    2017-01-01

    The High Luminosity-Large Hadron Collider (HL-LHC) is expected to start in 2026 and to pro- vide an integrated luminosity of 3000 fb−1 in ten years, a factor 10 more than what will be collected by 2023. This high statistics will allow ATLAS to perform precise measurements in the Higgs sector and improve searches for new physics at the TeV scale. The luminosity needed is L ∼ 7.51034 cm−2 s−1, corresponding to ∼200 additional proton-proton pile- up interactions. To face such harsh environment some sub-detectors of the ATLAS experiment will be upgraded or completely substituted. The performances of the new or upgraded ATLAS sub-detectors are presented, focusing in particular on the new inner tracker and a proposed high granularity time device. The impact of those upgrades on crucial physics measurements for HL-LHC program is also shown.

  12. Performance and Operational Aspects of HL-LHC Scenarios

    CERN Document Server

    Medina Medrano, Luis

    2016-01-01

    Several alternatives to the present HL-LHC baseline configuration have been proposed, aiming either to improve the potential performance, reduce its risks, or to provide options for addressing possible limitations or changes in its parameters. In this paper we review and compare the performance of the HL-LHC baseline and the main alternatives with the latest parameters set. The results are obtained using refined simulations of the evolution of the luminosity with β^{*}-levelling, for which new criteria have been introduced, such as improved calculation of the intrabeam scattering and the addition of penalty steps to take into account the necessary time to move between consecutive optics during the process. The features of the set of optics are discussed for the nominal baseline.

  13. Peculiarities of the Accretion Flow in the System HL CMa

    CERN Document Server

    Semena, Andrey; Buckley, David; Lutovinov, Alexander; Breytenbach, Hannes

    2016-01-01

    The properties of the aperiodic brightness variability for the dwarf nova HL CMa are considered. The variability of the system HL CMa is shown to be suppressed at frequencies above $7\\times10^{-3}$Hz. Different variability suppression mechanisms related to the radiation reprocessing time, partial disk evaporation, and characteristic variability formation time are proposed. It has been found that the variability suppression frequency does not change when the system passes from the quiescent state to the outburst one, suggesting that the accretion flow geometry is invariable. It is concluded from the optical and X-ray luminosities of the system that the boundary layer on the white dwarf surface is optically thick in both quiescent and outburst states. The latter implies that the optically thick part of the accretion flow (disk) reaches the white dwarf surface. The accretion rate in the system, the flow geometry and temperature have been estimated from the variability power spectra and spectral characteristics i...

  14. Physics potential of ATLAS upgrades at HL-LHC

    CERN Document Server

    Testa, Marianna; The ATLAS collaboration

    2017-01-01

    The High Luminosity-Large Hadron Collider (HL-LHC) is expected to start in 2026 and to provide an integrated luminosity of 3000 fb-1 in ten year, a factor 10 more than what will be collected by 2021. This high statistics will allow to perform precise measurements in the Higgs sector and improve searches of new physics at the TeV scale. The luminosity needed is L ~7.5 1034 cm-2 s-1, correspondent to ~200 additional proton-proton pile-up interactions. To face such harsh environment some sub-detectors of the ATLAS experiment will be upgraded or completely substituted. In this poster, the performances of the new or upgraded ATLAS sub-detectors will be described, focusing in particular on the new inner tracker and a proposed high granularity time device. The poster will also show the impact of those upgrades on crucial physics measurements for HL-LHC program

  15. Parameters for aperture calculations at injection for HL-LHC*

    CERN Document Server

    Bruce, Roderik; De Maria, Riccardo; Giovannozzi, Massimo; Redaelli, Stefano; Tomas Garcia, Rogelio; Velotti, Francesco Maria; Wenninger, Jorg

    2016-01-01

    Accurate evaluations of the margins of available aperture in the LHC and HL-LHC are very important, in order to judge if proposed optics and hardware are adequate, and to push the machine performance. A 2D calculation model was used during the design stage to study the aperture margins, however, the parameters of the model can now be refined based on LHC measurements and operational experience. This has already been carried out for the triplet aperture in the experimental insertions during physics operation [1]. In this report, we study instead the parameter sets for aperture calculations at injection for HL-LHC, and provide an updated set of tolerances as well as a criterion for the allowed aperture.

  16. Investigation of Lift Bonding for Roller-Compacted Concrete with Low Normal Loads at Variable Placement Times

    Science.gov (United States)

    2013-04-01

    concrete materials together. The maximum capacity of a single batch in this mixer is approximately 27 ft3. The aggregates are dumped from hydraulically...distributed into the mixer . Following the concrete sand, the ASTM #57 crushed limestone was weighed and added to the mixer . The two aggregates were...ER D C/ G SL T R -1 3 -7 Investigation of Lift Bonding for Roller- Compacted Concrete with Low Normal Loads at Variable Placement Times

  17. Remotely Adjustable Hydraulic Pump

    Science.gov (United States)

    Kouns, H. H.; Gardner, L. D.

    1987-01-01

    Outlet pressure adjusted to match varying loads. Electrohydraulic servo has positioned sleeve in leftmost position, adjusting outlet pressure to maximum value. Sleeve in equilibrium position, with control land covering control port. For lowest pressure setting, sleeve shifted toward right by increased pressure on sleeve shoulder from servovalve. Pump used in aircraft and robots, where hydraulic actuators repeatedly turned on and off, changing pump load frequently and over wide range.

  18. Data Warehouse Design from HL7 Clinical Document Architecture Schema.

    Science.gov (United States)

    Pecoraro, Fabrizio; Luzi, Daniela; Ricci, Fabrizio L

    2015-01-01

    This paper proposes a semi-automatic approach to extract clinical information structured in a HL7 Clinical Document Architecture (CDA) and transform it in a data warehouse dimensional model schema. It is based on a conceptual framework published in a previous work that maps the dimensional model primitives with CDA elements. Its feasibility is demonstrated providing a case study based on the analysis of vital signs gathered during laboratory tests.

  19. Ist Rausch ein Gefühl? : eine philosophische Exposition

    OpenAIRE

    Weber-Guskar, Eva

    2007-01-01

    'Die Verfasserin geht angesichts der Tatsache, dass der Begriff und die vielleicht vage Sache des 'Rausches' unter manchen Historikern eine gewisse Konjunktur haben, in ihrer 'philosophischen Exposition' der Frage nach: 'Ist Rausch ein Gefühl?' Indem sie zunächst den Sprachgebrauch analysiert, sucht sie auf 'konzeptionelle Unstimmigkeiten hinzuweisen, die sich in den verstreuten Definitionsteilen finden'. Ihre These lautet, dass 'der (...) Vorstellung von Massenrausch eine schiefe Vorstellung...

  20. B-physics studies for HL-LHC ATLAS upgrade

    CERN Document Server

    Jakoubek, Tomas; The ATLAS collaboration

    2017-01-01

    Simulation studies were made to estimate ATLAS HL-LHC upgrade performance for B-physics. In particular, the decay of $B_s^0 \\to J/\\psi\\phi$ is studied in order to measures the $CP$ violating mixing phase and the width difference between the $B_s^0$ eigenstates. The increased sensitivity is related mainly to the improved decay time resolution obtained with the upgraded ITk inner tracking detector.

  1. Cost Benefit Analysis of Boat Lifts

    Science.gov (United States)

    2014-09-01

    to avoid the potential of mishaps due to jumping across open water to reach both sides of the lift. With the life expectancy of a boat ramp...to jumping across open water to reach both sides of the lift. Cost Benefit Analysis of Boat Lifts 11 UNCLAS//Public | CG-926 R&DC | B. Fike...equipment from boats and craft that have been corrosion problems in the past. such as wire rope and non-stainless steel hardware. Corrosion is a function

  2. Database queries and constraints via lifting problems

    CERN Document Server

    Spivak, David I

    2012-01-01

    Previous work has shown a tight relationship between databases and categories. In the present paper we extend that connection to show that certain queries and constraints correspond to the algebro-topological notion of lifting problems. In our formulation, each so-called SPARQL graph pattern query corresponds to a lifting problem, and each solution to the query corresponds to a lift. We interpret constraints within the same formalism and then investigate some formal properties of queries and constraints, e.g. their behavior under data migration functors.

  3. Undular Hydraulic Jump

    Directory of Open Access Journals (Sweden)

    Oscar Castro-Orgaz

    2015-04-01

    Full Text Available The transition from subcritical to supercritical flow when the inflow Froude number Fo is close to unity appears in the form of steady state waves called undular hydraulic jump. The characterization of the undular hydraulic jump is complex due to the existence of a non-hydrostatic pressure distribution that invalidates the gradually-varied flow theory, and supercritical shock waves. The objective of this work is to present a mathematical model for the undular hydraulic jump obtained from an approximate integration of the Reynolds equations for turbulent flow assuming that the Reynolds number R is high. Simple analytical solutions are presented to reveal the physics of the theory, and a numerical model is used to integrate the complete equations. The limit of application of the theory is discussed using a wave breaking condition for the inception of a surface roller. The validity of the mathematical predictions is critically assessed using physical data, thereby revealing aspects on which more research is needed

  4. Ascorbic acid modulates cell migration in differentiated HL-60 cells and peripheral blood leukocytes.

    Science.gov (United States)

    Schwager, Joseph; Bompard, Albine; Weber, Peter; Raederstorff, Daniel

    2015-08-01

    The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated HL-cells were assayed. Vitamin D3-treated HL-60 cells (dHL-60vitD3 cells) and RA-treated cells (dHL-60RA cells) acquired monocyte/macrophage-like and neutrophil-like phenotypes, respectively. DMSO induced the differentiation of an intermediate phenotype (dHL-60DMSO cells), whereas L-AA downregulated neutrophil markers (dHL-60L-AA cells). dHL-60DMSO cells had increased CK and potent CT in gradients of IL-8 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP). dHL-60RA cells and dHL-60L-AA cells migrated less toward IL-8 and fMLP; dHL-60vitD3 cells preferably responded to fMLP. L-AA enhanced CK of dHL-60DMSO cells and was a weak chemo-attractant. In human leukocytes, IL-8 and fMLP triggered receptor-mediated chemotaxis. CXCR2 and fMLPR were downregulated by IL-8 and fMLP, respectively. L-AA stimulated chemotaxis although significantly less than IL-8 and fMLP. IL-8 targeted chemotaxis was enhanced both in HL-60 cells and leukocytes when cells were incubated with L-AA. L-AA modulated chemokinesis and had significant chemo-attractant properties, which were independent on fMLP or IL-8 receptors. The results suggest that L-AA improves leukocyte function in innate immune responses. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Energy Released During the H-L Back Transition

    Science.gov (United States)

    Eldon, D.; Kolemen, E.; Gohil, P.; McKee, G. R.; Yan, Z.; Schmitz, L.

    2015-11-01

    Prompt energy loss (ΔW) at the H-L transition, as a fraction of total stored energy before the transition, is about 30 % and is insensitive to density in ITER-similar DIII-D plasmas. Occasionally, some ELMs will appear before the transition and reduce total energy, thus reducing ΔW across the following transition. Other results (not in the ITER-similar shape) have shown that ELMs can be triggered in low powered H-modes, prior to H-L transitions, when the plasma is stable to ideal P-B modes (these are not typical type-I ELMs, despite superficial similarities) and E × B shear is strong. These are indeed ELMs occurring in H-mode and not part of a dithering transition. Finally, ELM ΔW is sensitive to edge toroidal rotation and becomes smaller than uncertainty (point to a strategy where ΔW for the H-L transition may be reduced by the presence of (not type-I) ELMs before the transition, and ΔW for the ELMs may be reduced by controlling rotation. Work supported by the US Department of Energy under DE-AC02-09CH11466 and DE-FC02-04ER54698.

  6. Pixel Hybridization Technologies for the HL-LHC

    Science.gov (United States)

    Alimonti, G.; Biasotti, M.; Ceriale, V.; Darbo, G.; Gariano, G.; Gaudiello, A.; Gemme, C.; Rossi, L.; Rovani, A.; Ruscino, E.

    2016-12-01

    During the 2024-2025 shut-down, the Large Hadron Collider (LHC) will be upgraded to reach an instantaneous luminosity up to 7×1034 cm-2s-1. This upgrade of the collider is called High-Luminosity LHC (HL-LHC). ATLAS and CMS detectors will be upgraded to meet the new challenges of HL-LHC: an average of 200 pile-up events in every bunch crossing and an integrated luminosity of 3000 fb-1 over ten years. In particular, the current trackers will be completely replaced. In HL-LHC the trackers should operate under high fluences (up to 1.4 × 1016 neq cm-2), with a correlated high radiation damage. The pixel detectors, the innermost part of the trackers, needed a completely new design in the readout electronics, sensors and interconnections. A new 65 nm front-end (FE) electronics is being developed by the RD53 collaboration compatible with smaller pixel sizes than the actual ones to cope with the high track densities. Consequently the bump density will increase up to 4 ·104 bumps/cm2. Preliminary results of two hybridization technologies study are presented in this paper. In particular, the on-going bump-bonding qualification program at Leonardo-Finmeccanica is discussed, together with alternative hybridization techniques, as the capacitive coupling for HV-CMOS detectors.

  7. Tetramethylpyrazine potentiates arsenic trioxide activity against HL-60 cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yuni; Xu, Youhua; Shen, Yali; Wang, Cuicui; Guo, Gaili; Hu, Tiantian [Key Laboratory of Developmental Diseases in Childhood, Chongqing (China); Key Laboratory of Pediatrics in Chongqing, Chongqing (China); Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing (China)

    2012-02-17

    The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As{sub 2}O{sub 3}) on the proliferation and differentiation of HL-60 cells. The HL-60 cells were treated with 300 µg/mL TMP, 0.5 µM As{sub 2}O{sub 3}, and 300 µg/mL TMP combined with 0.5 µM As{sub 2}O{sub 3}, respectively. The proliferative inhibition rates were determined with MTT. Differentiation was detected by the nitroblue tetrazolium (NBT) reduction test, Wright's staining and the distribution of CD11b and CD14. Flow cytometry was used to analyze cell cycle distribution. RT-PCR and Western blot assays were employed to detect the expressions of c-myc, p27, CDK2, and cyclin E1. Combination treatment had synergistic effects on the proliferative inhibition rates. The rates were increased gradually after the combination treatment, much higher than those treated with the corresponding concentration of As{sub 2}O{sub 3} alone. The cells exhibited characteristics of mature granulocytes and a higher NBT-reducing ability, being a 2.6-fold increase in the rate of NBT-positive ratio of HL-60 cells within the As{sub 2}O{sub 3} treatment versus almost a 13-fold increase in the TMP + As{sub 2}O{sub 3} group. Cells treated with both TMP and As{sub 2}O{sub 3} expressed far more CD11b antigens, almost 2-fold compared with the control group. Small doses of TMP potentiate As{sub 2}O{sub 3}-induced differentiation of HL-60 cells, possibly by regulating the expression and activity of G0/G1 phase-arresting molecules. Combination treatment of TMP with As{sub 2}O{sub 3} has significant synergistic effects on the proliferative inhibition of HL-60 cells.

  8. Hydraulic System Design of Hydraulic Actuators for Large Butterfly Valves

    OpenAIRE

    HUANG, Ye; Liu, Changsheng; Shiongur Bamed

    2014-01-01

    Hydraulic control systems of butterfly valves are presently valve-controlled and pump-controlled. Valve-controlled hydraulic systems have serious power loss and generate much heat during throttling. Pump-controlled hydraulic systems have no overflow or throttling losses but are limited in the speed adjustment of the variable-displacement pump, generate much noise, pollute the environment, and have motor power that does not match load requirements, resulting in low efficiency under...

  9. Lambda-Lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, Olivier; Schultz, Ulrik Pagh

    2002-01-01

    Lambda-lifting is a program transformation used in compilers and in partial evaluators and that operates in cubic time. In this article, we show how to reduce this complexity to quadratic time. Lambda-lifting transforms a block-structured program into a set of recursive equations, one for each...... local function in the source program. Each equation carries extra parameters to account for the free variables of the corresponding local function and of all its callees. It is the search for these extra parameters that yields the cubic factor in the traditional formulation of lambda-lifting, which...... is not needed. We therefore simplify the search for extra parameters by treating each strongly connected component instead of each function as a unit, thereby reducing the time complexity of lambda-lifting from O(n 3 log n)toO(n2 log n), where n is the size of the program. Since a lambda-lifter can output...

  10. Lower complexity bounds for lifted inference

    DEFF Research Database (Denmark)

    Jaeger, Manfred

    2015-01-01

    instances of the model. Numerous approaches for such “lifted inference” techniques have been proposed. While it has been demonstrated that these techniques will lead to significantly more efficient inference on some specific models, there are only very recent and still quite restricted results that show...... the feasibility of lifted inference on certain syntactically defined classes of models. Lower complexity bounds that imply some limitations for the feasibility of lifted inference on more expressive model classes were established earlier in Jaeger (2000; Jaeger, M. 2000. On the complexity of inference about...... that under the assumption that NETIME≠ETIME, there is no polynomial lifted inference algorithm for knowledge bases of weighted, quantifier-, and function-free formulas. Further strengthening earlier results, this is also shown to hold for approximate inference and for knowledge bases not containing...

  11. Spherical projections and liftings in geometric tomography

    DEFF Research Database (Denmark)

    Goodey, Paul; Kiderlen, Markus; Weil, Wolfgang

    2011-01-01

    We consider a variety of integral transforms arising in Geometric Tomography. It will be shown that these can be put into a common framework using spherical projection and lifting operators. These operators will be applied to support functions and surface area measures of convex bodies and to rad......We consider a variety of integral transforms arising in Geometric Tomography. It will be shown that these can be put into a common framework using spherical projection and lifting operators. These operators will be applied to support functions and surface area measures of convex bodies...... and to radial functions of star bodies. We then investigate averages of lifted projections and show that they correspond to self-adjoint intertwining operators. We obtain formulas for the eigenvalues of these operators and use them to ascertain circumstances under which tomographic measurements determine...... the original bodies. This approach via mean lifted projections leads us to some unexpected relationships between seemingly disparate geometric constructions....

  12. Lifting scheme of symmetric tight wavelets frames

    Institute of Scientific and Technical Information of China (English)

    ZHUANG BoJin; YUAN WeiTao; PENG LiZhong

    2008-01-01

    This paper proposes a method to realize the lifting scheme of tight frame wavelet filters. As for 4-channel tight frame wavelet filter, the tight frame transforms' ma-trix is 2×4, but the lifting scheme transforms' matrix must be 4×4. And in the case of 3-channel tight frame wavelet filter, the transforms' matrix is 2×3, but the lifting scheme transforms' matrix must be 3×3. In order to solve this problem, we intro-duce two concepts: transferred polyphase matrix for 4-channel filters and trans-ferred unitary matrix for 3-channel filters. The transferred polyphase matrix is sym-metric/antisymmetric. Thus, we use this advantage to realize the lifting scheme.

  13. Experimental determination of baseball spin and lift.

    Science.gov (United States)

    Alaways, L W; Hubbard, M

    2001-05-01

    The aim of this study was to develop a new method for the determination of lift on spinning baseballs. Inertial trajectories of (a) ball surface markers during the first metre of flight and (b) the centre of mass trajectory near home-plate were measured in a pitch using high-speed video. A theoretical model was developed, incorporating aerodynamic Magnus-Robins lift, drag and cross forces, which predicts the centre of mass and marker trajectories. Parameters including initial conditions and aerodynamic coefficients were estimated iteratively by minimizing the error between predicted and measured trajectories. We compare the resulting lift coefficients and spin parameter values with those of previous studies. Lift on four-seam pitches can be as much as three times that of two-seam pitches, although this disparity is reduced for spin parameters greater than 0.4.

  14. Design of heavy lift cargo aircraft

    Data.gov (United States)

    National Aeronautics and Space Administration — This is the bird of the skies of the future. The heavy lift cargo aircraft which is currently being developed by me has twice the payload capacity of an Antonov...

  15. Hydraulic System Design of Hydraulic Actuators for Large Butterfly Valves

    Directory of Open Access Journals (Sweden)

    Ye HUANG

    2014-09-01

    Full Text Available Hydraulic control systems of butterfly valves are presently valve-controlled and pump-controlled. Valve-controlled hydraulic systems have serious power loss and generate much heat during throttling. Pump-controlled hydraulic systems have no overflow or throttling losses but are limited in the speed adjustment of the variable-displacement pump, generate much noise, pollute the environment, and have motor power that does not match load requirements, resulting in low efficiency under light loads and wearing of the variable-displacement pump. To overcome these shortcomings, this article designs a closed hydraulic control system in which an AC servo motor drives a quantitative pump that controls a spiral swinging hydraulic cylinder, and analyzes and calculates the structure and parameters of a spiral swinging hydraulic cylinder. The hydraulic system adjusts the servo motor’s speed according to the requirements of the control system, and the motor power matches the power provided to components, thus eliminating the throttling loss of hydraulic circuits. The system is compact, produces a large output force, provides stable transmission, has a quick response, and is suitable as a hydraulic control system of a large butterfly valve.

  16. Integrated lift/drag controller for aircraft

    Science.gov (United States)

    Olcott, J. W.; Seckel, E.; Ellis, D. R. (Inventor)

    1974-01-01

    A system for altering the lift/drag characteristics of powered aircraft to provide a safe means of glide path control includes a control device integrated for coordination action with the aircraft throttle. Such lift/drag alteration devices as spoilers, dive brakes, and the like are actuated by manual operation of a single lever coupled with the throttle for integrating, blending or coordinating power control. Improper operation of the controller is inhibited by safety mechanisms.

  17. Reliability assessment and measures for resources-saving on water lifting engine systems in Uzbekistan

    Directory of Open Access Journals (Sweden)

    Bakhtier Ergashev

    2010-02-01

    Full Text Available The paper observes the current state of water pumping stations in Uzbekistan. More than 50% of irrigated land is provided with machine water lifting systems in the country. However, more than 50% of pumping aggregates and constructions have used up their capacities that leads to high operational expenses of energy. The authors suggest develop energy- and resource saving technologies. As they suggest the resource saving model assumes first and foremost the increase in stability and efficiency of operation of all elements of hydraulic engineering.

  18. Plunger lift analysis, troubleshooting and optimization

    Energy Technology Data Exchange (ETDEWEB)

    Rowlan, O.L.; McCoy, J.N. [Echometer Co., Wichita Falls, TX (United States); Podio, A.L. [Texas Univ. at Austin, Austin, TX (United States)

    2007-07-01

    Plunger lifting is used to lift liquids such as condensates, water and oil from liquid loaded gas wells. This paper described a portable system designed to monitor gas plunger lift. The system digitized, stored and processed acoustic pulse signals generated by the plunger as it fell through each tubing collar recess when the well was shut in. Data were used to determine depth; fall velocity; the amount of appropriate cycle times for optimum operation; and the volume and rate of gas flowing into the well. The stored signals were then used to determine plunger position, plunger fall velocity, and plunger arrival at the liquid level in the tubing. Analysis of the data were used to optimize and troubleshoot the operation of plunger lifted wells. Examples of various operational problems encountered during the operation of the plunger lift system were also provided. It was concluded that the monitoring system increases the safety of plunger lift operations by allowing operators to know the exact placement of the plunger. 5 refs., 1 tab., 17 figs.

  19. Importance of inducible multidrug resistance 1 expression in HL-60 cells resistant to gemtuzumab ozogamicin.

    Science.gov (United States)

    Matsumoto, Taichi; Jimi, Shiro; Hara, Shuuji; Takamatsu, Yasushi; Suzumiya, Junji; Tamura, Kazuo

    2012-07-01

    Resistance to gemtuzumab ozogamicin (GO) hampers the effective treatment of refractory acute myeloid leukemia (AML). To clarify the mechanism of resistance to GO, HL-60 cells were persistently exposed to GO in order to establish GO-resistant HL-60 (HL-60/GOR) cells. Multidrug resistance 1 (MDR-1) was strongly expressed in HL-60/GOR cells, but not in HL-60 cells. Although withdrawal of GO after the chronic exposure of HL-60/GOR cells to this compound gradually decreased MDR-1 expression to trace levels, reintroducing GO restored high MDR-1 expression in HL-60/GOR cells, but not in HL-60 cells. These results indicate that HL-60/GOR cells acquired the ability to induce MDR-1 expression in response to GO. U0126, a MEK1/2 inhibitor, prevented GO-inducible MDR-1 expression and abrogated GO resistance in HL-60/GOR cells. These results suggest that in the clinical use of GO, inducible MDR-1 expression in tumor cells should be investigated before treatment with GO. If the cells are positive then MEK1/2 inhibitors may be effective in overcoming resistance to GO.

  20. Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.

    Science.gov (United States)

    Boomsma, Robert A; Geenen, David L

    2014-01-01

    This study examined the interaction of mouse bone marrow mesenchymal stem cells (MSC) with cardiac HL-1 cells during coculture by fluorescent dye labeling and then flow cytometry. MSC were layered onto confluent HL-1 cell cultures in a 1 : 4 ratio. MSC gained gap junction permeant calcein from HL-1 cells after 4 hours which was partially reduced by oleamide. After 20 hours, 99% MSC gained calcein, unaffected by oleamide. Double-labeling HL-1 cells with calcein and the membrane dye DiO resulted in transfer of both calcein and DiO to MSC. When HL-1 cells were labeled with calcein and MSC with DiO, MSC gained calcein while HL-1 cells gained DiO. Very little fusion was observed since more than 90% Sca-1 positive MSC gained DiO from HL-1 cells while less than 9% gained gap junction impermeant CMFDA after 20 hours with no Sca-1 transfer to HL-1 cells. Time dependent transfer of membrane DiD was observed from HL-1 cells to MSC (100%) and vice versa (50%) after 20 hours with more limited transfer of CMFDA. These results demonstrate that MSC and HL-1 cells exchange membrane components which may account for some of the beneficial effect of MSC in the heart after myocardial infarction.

  1. 14 CFR 25.697 - Lift and drag devices, controls.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Lift and drag devices, controls. 25.697....697 Lift and drag devices, controls. (a) Each lift device control must be designed so that the pilots....101(d). Lift and drag devices must maintain the selected positions, except for movement produced by an...

  2. Modelling of Hydraulic Robot

    DEFF Research Database (Denmark)

    Madsen, Henrik; Zhou, Jianjun; Hansen, Lars Henrik

    1997-01-01

    This paper describes a case study of identifying the physical model (or the grey box model) of a hydraulic test robot. The obtained model is intended to provide a basis for model-based control of the robot. The physical model is formulated in continuous time and is derived by application...... of the laws of physics on the system. The unknown (or uncertain) parameters are estimated with Maximum Likelihood (ML) parameter estimation. The identified model has been evaluated by comparing the measurements with simulation of the model. The identified model was much more capable of describing the dynamics...... of the system than the deterministic model....

  3. Hydraulic mining method

    Science.gov (United States)

    Huffman, Lester H.; Knoke, Gerald S.

    1985-08-20

    A method of hydraulically mining an underground pitched mineral vein comprising drilling a vertical borehole through the earth's lithosphere into the vein and drilling a slant borehole along the footwall of the vein to intersect the vertical borehole. Material is removed from the mineral vein by directing a high pressure water jet thereagainst. The resulting slurry of mineral fragments and water flows along the slant borehole into the lower end of the vertical borehole from where it is pumped upwardly through the vertical borehole to the surface.

  4. Spinning hydraulic jump

    Science.gov (United States)

    Abderrahmane, Hamid; Kasimov, Aslan

    2013-11-01

    We report an experimental observation of a new symmetry breaking of circular hydraulic jump into a self-organized structure that consists of a spinning polygonal jump and logarithmic-spiral waves of fluid elevation downstream. The waves are strikingly similar to spiral density waves in galaxies. The fluid flow exhibits counterparts of salient morphological features of galactic flows, in particular the outflow from the center, jets, circum-nuclear rings, gas inflows toward the galactic center, and vortices. The hydrodynamic instability revealed here may have a counterpart that plays a role in the formation and sustainability of spiral arms in galaxies.

  5. 46 CFR 28.880 - Hydraulic equipment.

    Science.gov (United States)

    2010-10-01

    ... hydraulic equipment and the adjacent work area. Protection shall be afforded to the operator of hydraulic... 46 Shipping 1 2010-10-01 2010-10-01 false Hydraulic equipment. 28.880 Section 28.880 Shipping... INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.880 Hydraulic equipment. (a) Each hydraulic system must...

  6. Applied hydraulic transients

    CERN Document Server

    Chaudhry, M Hanif

    2014-01-01

    This book covers hydraulic transients in a comprehensive and systematic manner from introduction to advanced level and presents various methods of analysis for computer solution. The field of application of the book is very broad and diverse and covers areas such as hydroelectric projects, pumped storage schemes, water-supply systems, cooling-water systems, oil pipelines and industrial piping systems. Strong emphasis is given to practical applications, including several case studies, problems of applied nature, and design criteria. This will help design engineers and introduce students to real-life projects. This book also: ·         Presents modern methods of analysis suitable for computer analysis, such as the method of characteristics, explicit and implicit finite-difference methods and matrix methods ·         Includes case studies of actual projects ·         Provides extensive and complete treatment of governed hydraulic turbines ·         Presents design charts, desi...

  7. Efflux of potassium ion is an important reason of HL-60 cells apoptosis induced by tachyplesin

    Institute of Scientific and Technical Information of China (English)

    Hai-tao ZHANG; Jun WU; Hai-feng ZHANG; Qi-feng ZHU

    2006-01-01

    Aim: To investigate the role of intercellular potassium in tachyplesin-induced HL-60 cells apoptosis. Methods: The concentration of intercellular potassium, cell volume and mitochondrial membrane potential were examined by flow cytometry. Results: The concentration of intercellular potassium reduced in a time-dependent manner in tachyplesin-treated HL-60 cells. In addition, the loss of mitochondrial membrane potential was tightly coupled with the shrinkage of cell volume. Different caspase inhibitors protected against DNA degradation but did not prevent the loss of HL-60 cell viability induced by tachyplesin. Ba2+, which was a kind of blocker of volume-regulatory K+ channels, increased the viability of tachyplesin-treated HL-60 cells and maintained mitochondrial membrane potential and cell volume. Conclusion: Efflux of K+ was an important reason for apoptosis in tachyplesin-treated HL-60 cells. Efflux of K+ affected the viability of tachyplesin-treated HL-60 cells independent of the process of caspase activation.

  8. 77 FR 20558 - Federal Motor Vehicle Safety Standards; Platform Lifts for Motor Vehicles; Platform Lift...

    Science.gov (United States)

    2012-04-05

    ... National Highway Traffic Safety Administration 49 CFR Part 571 RIN 2127-AJ93 Federal Motor Vehicle Safety Standards; Platform Lifts for Motor Vehicles; Platform Lift Installations in Motor Vehicles AGENCY: National.... SUMMARY: This document adopts amendments to the Federal motor vehicle safety standards on platform...

  9. Optic diagnosis of neutral beam injection on HL-1M

    Institute of Scientific and Technical Information of China (English)

    郑银甲; 冯震; 雷光玖; 姜韶风; 卢大伦; 罗俊林

    2002-01-01

    During the operation of a high-power neutral beam injection (NBI) system on the H L-1M tokamak, an optical diagnostic means using CCD camera was developed to characterize the NBI performance. The vacuum valve opening process and NBI period in the HL-1M experiment were displayed by a lot of photos taken with this means. Thus, the Hα emission profiles of the neutral beam (NB) and its interaction with plasma were given. Finally, the reason possible for plasma breakdown during NBI mode Ⅱ discharge was investigated. Therefore, this in-situ diagnosis can provide more information of the NBI.

  10. B-physics studies for HL-LHC ATLAS upgrade

    CERN Document Server

    Jakoubek, Tomas; The ATLAS collaboration

    2017-01-01

    Performance studies are made to estimate the ATLAS potential in $B$-physics after upgrade for Run2 and HL-LHC. Real data as well as Monte Carlo simulations are used to study the decay of $B^0_s \\to J/\\psi\\phi$ in order to measure the $CP$ violating mixing phase and the width difference between the $B^0_s$ eigenstates. The increased sensitivity is expected mainly due to the improved decay time resolution obtained with the upgraded IBL and ITk inner tracking detector.

  11. Neutral Beam Injection Experiments in the HL-1M Tokamak

    Institute of Scientific and Technical Information of China (English)

    严龙文; 雷光玖; 钟光武; 江涛; 周艳; 姜韶风; 丁玄同; 周才品; 刘永

    2003-01-01

    Neutral beam injection (NBI) experiments have been carried out with two operation modes of a bucket ion source in the HL-1M tokamak. During the first mode, more than 30% rise in ion temperature above the Ohmic level is routinely achieved after NBI power about 0. 5 MW is injected. Ion temperature only increases 20-30% for the second operation mode, which is often limited by current termination. The heating effects of the NBI have been analysed experimentally and theoretically. The performance of the NBI system is well described.

  12. [Mechanism of HL-60 cells apoptosis induced by proteasome inhibitor MG132].

    Science.gov (United States)

    Zhou, Yong-Ming; Yu, Mei-Xia; Qiu, Yu-Zhen; Xing, Xiao-Lei; Yao, Chun-Hong; Bai, Ru-Jun

    2013-08-01

    The purpose of this study was to elucidate the apoptosis, apoptotic pathway of HL-60 cells induced by proteasome inhibitor MG132 and its effect on allogeneic mixed lymphocyte reaction. Apoptosis of HL-60 cells was detected by flow cytometry, the expression of P21, P27 and P53 proteins in HL-60 cells treated with MG132 was assayed by Western blot. The HL-60 cells were treated with 1 µmol/L MG132 for 48 h, and irradiated by 75 Gy of (60)Co γ-ray, but their antigenicity was preserved. The effect of irradiated HL-60 cells treated with MG132 on proliferation of peripheral blood mononuclear cells (PBMNC) was measured by CCK-8 method. The results showed that the apoptotic rate of MG132-treated HL-60 cells increased in dose-and time-dependent manner. No significant changes in MG132-induced apoptosis were observed after inhibiting caspase-8 and caspase-9 pathway. The expression of P21 and P27 protein increased after treatment of HL-60 cells with MG132. CCK-8 test showed that HL-60 cells induced with low-dose of MG132 displayed the enhancing effect on proliferation of PBMNC. It is concluded that high dose of MG132 can induce the apoptosis of HL-60 cells, and has direct killing effect on HL-60 cells, but this inducing apoptotic effect on HL-60 cells can not be realized through caspase-8 and caspase-9 pathway. The P21 and P27 protein may be involved in MG132 induced HL-60 cell apoptosis. Low dose of MG132 promotes the proliferation of PBMNC in healthy individuals and enhance the immunity of organism.

  13. HL7标准下的医疗信息系统融合%The Fusion for Health Care Information System Based on HL7 Standard

    Institute of Scientific and Technical Information of China (English)

    蔡晓白

    2012-01-01

    简要介绍HL7标准,分析HL7的消息结构、消息构造与解析、HL7引擎的服务器与客户端体系模块,并从中间件的角度研究HL7应用的实现技术及其可以利用的资源,包括TinyXML,Chameleon,SOCKET套接字接口,Iguana。为分布式的异构医疗信息系统整合提出一个基于中间件技术的解决方案。%The paper briefly introduces HL7 standard,analyzes the message structure,message construction and analysis,server and client system of HL7 engine,studies the realization technologies of HL7 application from the aspect of middleware,as well as available resources, including TinyXML,Chameleon,SOCKET interface,Iguana.It provides a middleware technology bated solution for distributed and different structured health care information system integration.

  14. EGCG抑制HL-60细胞增殖作用的机制研究%Study of EGCG Inhibited Proliferation of HL-150 Cells

    Institute of Scientific and Technical Information of China (English)

    欧阳琳; 姜浩

    2011-01-01

    目的 探讨EGCG抑制白血病HL-60细胞增殖的作用机制.方法 采用软琼脂集落形成实验和绘制细胞生长曲线,检测EGCG对HL-60细胞增殖的影响;FCM及DNA凝胶电泳法检测ECCG处理HL-60细胞后的凋亡情况;实时荧光定量RT-PCR和Wester blotting检测AKT1的表达.结果 细胞生长曲线和软琼脂集落形成实验结果均显示EGCG呈浓度依赖性抑制HL-60细胞的增殖(P<0.05);FCM及DNA凝胶电泳法结果显示EGCG呈浓度依赖性诱导HL-60细胞的凋亡(P<0.05).实时荧光定量RT-PCR和Wester blotting结果显示EGCG浓度升高,HL-60细胞中AKT1的表达降低.结论 EGCG可能通过下调AKT1的表达,促进细胞凋亡,发挥其对HL-60细胞增殖的抑制作用.

  15. Reference thresholds for the TEN(HL) test for people with normal hearing.

    Science.gov (United States)

    Hansen, Andreas S; Raen, Øyvind; Moore, Brian C J

    2017-09-01

    To estimate normative values and repeatability of thresholds for the TEN(HL) test for diagnosing dead regions in the cochlea, as a function of signal frequency, TEN(HL) level, age and gender. The TEN(HL) test was administered twice for each ear of each participant using signal frequencies from 0.5 to 4 kHz and TEN(HL) levels of 30, 50 and 70 dB HL/ERBN. In all, 29 young participants and 8 older participants were tested. All had normal audiograms with no history of hearing problems. There was good repeatability across sessions. There was no significant effect of ear, gender or age group. The average signal-to-TEN ratio (STR) at threshold was close to 0 dB. For low signal frequencies, the STR at threshold varied only slightly with TEN(HL) level, but for the signal frequencies of 3 and 4 kHz the STR at threshold increased to about +2.7 dB for the TEN(HL) level of 70 dB/ERBN. For a high TEN(HL) level, the "normal" STR at threshold at 3 and 4 kHz is closer to +2 dB than to 0 dB. Further research is needed to assess whether the TEN(HL)-test criteria need to be modified when testing at high frequencies and high levels.

  16. [Effect of 5-aza-2'-deoxycytidine on DAPK gene expression in human HL-60 cells].

    Science.gov (United States)

    Wang, Chun-Yan; Liu, Wen-Jun

    2014-06-01

    This study was aimed to investigate the effect of methylation transferase inhibitor 5-aza-2'-deoxycytidine (5-aza-2dC) of different concentrations on the apoptosis of human acute myeloid leukemia (AML) cell line HL-60 and the expression of DAPK gene in HL-60 cells, as well as to explore the possible anti-AML mechanism of 5-aza-2dC. HL-60 cells were treated by 5-aza-2dC of different concentrations. The effect of 5-aza-2dC on the HL-60 cell morphology was observed by Wright's staining. The effect of 5-aza-2dC on HL-60 cell apoptosis and DAPK mRNA expression was detected by flow cytometry and reverse transcription-polymerize chain reaction (RT-PCR) respectively. The results showed that the 5-aza-2dC induced the apoptosis of HL-60 cells in a concentration-dependent manner; the 5-aza-2dC increased the expression levels of DAPK mRNA in HL-60 cells in a concentration-dependent manner. It is concluded that the apoptosis rate of HL-60 cells and DAPK mRNA expression level displayed a rising trend with 5-aza-2dC concentration increasing. Therefore, DAPK gene may participate in HL-60 cell apoptosis induced by 5-aza-2dC.

  17. Hydraulic rams; a comparative investigation

    NARCIS (Netherlands)

    Tacke, J.H.P.M.

    1988-01-01

    A mathematical model describing the essential features of hydraulic ram operation is developed in order to clarify the possibilities and limitations of the ram relative to its site and its adjustments. The model distinguishes three different periods in the pumping cycle of the hydraulic ram: acceler

  18. Hydraulics. FOS: Fundamentals of Service.

    Science.gov (United States)

    John Deere Co., Moline, IL.

    This manual on hydraulics is one of a series of power mechanics texts and visual aids for training in the servicing of agricultural and industrial machinery. Focus is on oil hydraulics. Materials provide basic information and illustrations for use by vocational students and teachers as well as shop servicemen and laymen. The twelve chapters focus…

  19. Win a lift to the future!

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    The Communication Group is organising a competition offering people at CERN the chance to submit their ideas and win a ticket to the Lift10 Conference, which will be held in Geneva from 5 to7 May.   Lift is a community of technology "pioneers", created in 2006. It now involves more than 4,000 people from over 60 countries, who meet regularly in Europe and in Asia to explore the social implications of new technologies and the major shifts ahead. CERN is one of the academic partners of the next Lift conference, whose theme is "Connected people”. For this occasion, 10 free tickets to the conference will be awarded to the "CERNois" who come up with the best answers to the question: “How would you contribute to Lift10?” Those taking part in the competition can choose from among the following categories: - run workshop(s); - cover the conference on a blog; - coordinate a discussion during the breaks; - organize a lift@home ...

  20. Lift and wakes of flying snakes

    CERN Document Server

    Krishnan, Anush; Vlachos, Pavlos P; Barba, L A

    2013-01-01

    Flying snakes use a unique method of aerial locomotion: they jump from tree branches, flatten their bodies and undulate through the air to produce a glide. The shape of their body cross-section during the glide plays an important role in generating lift. This paper presents a computational investigation of the aerodynamics of the cross-sectional shape. We performed two-dimensional simulations of incompressible flow past the anatomically correct cross-section of the species Chrysopelea paradisi, showing that a significant enhancement in lift appears at an angle of attack of 35 degrees, above Reynolds numbers 2000. Previous experiments on physical models also obtained an increased lift, at the same angle of attack. The flow is inherently three-dimensional in physical experiments, due to fluid instabilities, and it is thus intriguing that the enhanced lift appears also in the two-dimensional simulations. The simulations point to the lift enhancement arising from the early separation of the boundary layer on the ...

  1. Precision markedly attenuates repetitive lift capacity.

    Science.gov (United States)

    Collier, Brooke R; Holland, Laura; McGhee, Deirdre; Sampson, John A; Bell, Alison; Stapley, Paul J; Groeller, Herbert

    2014-01-01

    This study investigated the effect of precision on time to task failure in a repetitive whole-body manual handling task. Twelve participants were required to repetitively lift a box weighing 65% of their single repetition maximum to shoulder height using either precise or unconstrained box placement. Muscle activity, forces exerted at the ground, 2D body kinematics, box acceleration and psychophysical measures of performance were recorded until task failure was reached. With precision, time to task failure for repetitive lifting was reduced by 72%, whereas the duration taken to complete a single lift and anterior deltoid muscle activation increased by 39% and 25%, respectively. Yet, no significant difference was observed in ratings of perceived exertion or heart rate at task failure. In conclusion, our results suggest that when accuracy is a characteristic of a repetitive manual handling task, physical work capacity will decline markedly. The capacity to lift repetitively to shoulder height was reduced by 72% when increased accuracy was required to place a box upon a shelf. Lifting strategy and muscle activity were also modified, confirming practitioners should take into consideration movement precision when evaluating the demands of repetitive manual handling tasks.

  2. Facial thread lifting with suture suspension.

    Science.gov (United States)

    Tavares, Joana de Pinho; Oliveira, Carlos Augusto Costa Pires; Torres, Rodolfo Prado; Bahmad, Fayez

    2017-05-09

    The increased interest in minimally-invasive treatments, such as the thread lifting, with lower risk of complications, minimum length of time away from work and effectiveness in correcting ptosis and aging characteristics has led many specialists to adopt this technique, but many doubts about its safety and effectiveness still limit its overall use. To analyze data published in the literature on the durability of results, their effectiveness, safety, and risk of serious adverse events associated with procedures using several types of threading sutures. Literature review using the key words "thread lift", "barbed suture", "suture suspension" and "APTOS". Due to the scarcity of literature, recent reports of facial lifting using threads were also selected, complemented with bibliographical references. The first outcomes of facial lifting with barbed sutures remain inconclusive. Adverse events may occur, although they are mostly minor, self-limiting, and short-lived. The data on the maximum effect of the correction, the durability of results, and the consequences of the long-term suture stay are yet to be clarified. Interest in thread lifting is currently high, but this review suggests that it should not yet be adopted as an alternative to rhytidectomy. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  3. Lift mechanics of downhill skiing and snowboarding

    Science.gov (United States)

    Wu, Qianhong; Igci, Yesim; Andreopoulos, Yiannis

    2005-11-01

    A simplified mathematical model is derived to describe the lift mechanics of downhill skiing and snowboarding, where the lift contributions due to both the transiently trapped air and the compressed snow crystals are determined for the first time. Using Shimizu's empirical relation to predict the local variation in snow permeability, we employ force and moment analysis to predict the angle of attack of the planing surface, the penetration depth at the leading edge and the shift in the center of pressure for two typical snow types, fresh and wind-packed snow. We present numerical solutions for snowboarding and asymptotic analytic solutions for skiing for the case where there are no edging or turning maneuvers, which shows that approximately 50% of the total lift force is generated by the trapped air in the case of wind-packed snow for snowboarding and 40% for skiing. For highly permeable fresh powder snow the lift contribution from the pore air pressure drops to < 20%. This new theory is an extension of the series of studies on lift generation in highly compressible porous media.

  4. CERN takes off at Lift11

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    CERN was especially featured at the Lift11 conference, held in Geneva early this month. Tara Shears delivered a keynote speech at the event, while Paul Oortman Gerlings (DGS-SEE) and Erik van der Bij (BE-CO) – winners of the Bulletin’s Lift11 competition – organised the CERN workshop.   Paul Oortman Gerlings takes questions at CERN's Lift11 workshop. Lift11 was an opportunity for CERN to reach today’s innovators and developers. “The event was filled with people eager to learn new ideas, who were not afraid to ask questions,” says Tara Shears, physicist from the LHCb Collaboration who presented an update on the status of the LHC. “People were amazed by what goes on inside CERN, by our science, our facilities – even by the way we carry out our day-to-day work. It is a branch of fundamental research that really seems to inspire everyone.” A small Lift11 group had the chance to take a tour of CERN, ...

  5. System and method for controlling hydraulic pressure in electro-hydraulic valve actuation systems

    Energy Technology Data Exchange (ETDEWEB)

    Brennan, Daniel G; Marriott, Craig D; Cowgill, Joel; Wiles, Matthew A; Patton, Kenneth James

    2014-09-23

    A control system for an engine includes a first lift control module and a second lift control module. The first lift control module increases lift of M valves of the engine to a predetermined valve lift during a period before disabling or re-enabling N valves of the engine. The second lift control module decreases the lift of the M valves to a desired valve lift during a period after enabling or re-enabling the N valves of the engine, wherein N and M are integers greater than or equal to one.

  6. Hydraulic Stability of Accropode Armour

    DEFF Research Database (Denmark)

    Jensen, T.; Burcharth, H. F.; Frigaard, Peter

    , and to assess the influence of core permeability on the hydraulic stability of Accropodes. Two structures were examined, one with a relatively permeable core and one with a relatively impermeable core. In November/December 1995, Ph.D.-student Marten Christensen carried out the model tests on the structure...... with permeable core (crushed granite with a gradation of 5-8 mm). The outcome of this study is described in "Hydraulic Stability of Single-Layer Dolos and Accropode Armour Layers" by Christensen & Burcharth (1995). In January/February 1996, Research Assistant Thomas Jensen carried out a similar study......The present report describes the hydraulic model tests of Accropode armour layers carried out at the Hydraulics Laboratory at Aalborg University from November 1995 through March 1996. The objective of the model tests was to investigate the hydraulic stability of Accropode armour layers...

  7. Hydraulic Stability of Accropode Armour

    DEFF Research Database (Denmark)

    Jensen, T.; Burcharth, H. F.; Frigaard, Peter

    , and to assess the influence of core permeability on the hydraulic stability of Accropodes. Two structures were examined, one with a relatively permeable core and one with a relatively impermeable core. In November/December 1995, Ph.D.-student Marten Christensen carried out the model tests on the structure...... with permeable core (crushed granite with a gradation of 5-8 mm). The outcome of this study is described in "Hydraulic Stability of Single-Layer Dolos and Accropode Armour Layers" by Christensen & Burcharth (1995). In January/February 1996, Research Assistant Thomas Jensen carried out a similar study......The present report describes the hydraulic model tests of Accropode armour layers carried out at the Hydraulics Laboratory at Aalborg University from November 1995 through March 1996. The objective of the model tests was to investigate the hydraulic stability of Accropode armour layers...

  8. Upgrading the ATLAS Silicon Tracking for the HL-LHC

    CERN Document Server

    Barber, T; The ATLAS collaboration

    2012-01-01

    After successful operation of the LHC at a centre-of-mass energy of 8 TeV this year, the energy is expected to go up to 14 TeV in the next few years. A total integrated luminosity of 300 fb-1 foreseen to be reached by 2020. At that time, the LHC will undergo a major upgrade to the High Luminosity LHC (HL-LHC), which is designed to deliver of order five times the LHC nominal instantaneous luminosity along with luminosity leveling. The final goal is to extend the data set to 3000 fb-1 by around 2030. Current planning in ATLAS involves significant upgrades to the detector during the consolidation of the LHC to reach full LHC energy and further upgrades to accommodate running already beyond nominal luminosity this decade. The challenge of coping with HL-LHC instantaneous and integrated luminosity, along with the associated radiation levels, requires further major changes to the ATLAS detector. The designs are developing rapidly for an all-new inner-tracker, significant upgrades in the calorimeter and muon systems...

  9. The ATLAS tracker strip detector for HL-LHC

    CERN Document Server

    Cormier, Kyle James Read; The ATLAS collaboration

    2016-01-01

    As part of the ATLAS upgrades for the High Luminsotiy LHC (HL-LHC) the current ATLAS Inner Detector (ID) will be replaced by a new Inner Tracker (ITk). The ITk will consist of two main components: semi-conductor pixels at the innermost radii, and silicon strips covering larger radii out as far as the ATLAS solenoid magnet including the volume currently occupied by the ATLAS Transition Radiation Tracker (TRT). The primary challenges faced by the ITk are the higher planned read out rate of ATLAS, the high density of charged particles in HL-LHC conditions for which tracks need to be resolved, and the corresponding high radiation doses that the detector and electronics will receive. The ITk strips community is currently working on designing and testing all aspects of the sensors, readout, mechanics, cooling and integration to meet these goals and a Technical Design Report is being prepared. This talk is an overview of the strip detector component of the ITk, highlighting the current status and the road ahead.

  10. GRAIN SIZE CONSTRAINTS ON HL TAU WITH POLARIZATION SIGNATURE

    Energy Technology Data Exchange (ETDEWEB)

    Kataoka, Akimasa; Dullemond, Cornelis P [Zentrum für Astronomie der Universität Heidelberg, Institut für Theoretische Astrophysik, Albert-Ueberle-Str. 2, D-69120 Heidelberg (Germany); Muto, Takayuki [Division of Liberal Arts, Kogakuin University, 1-24-2 Nishi-Shinjuku, Shinjuku-ku, Tokyo 163-8677 (Japan); Momose, Munetake; Tsukagoshi, Takashi, E-mail: kataoka@uni-heidelberg.de [College of Science, Ibaraki University, 2-1-1 Bunkyo, Mito, Ibaraki 310-8512 (Japan)

    2016-03-20

    The millimeter-wave polarization of the protoplanetary disk around HL Tau has been interpreted as the emission from elongated dust grains aligned with the magnetic field in the disk. However, the self-scattering of thermal dust emission may also explain the observed millimeter-wave polarization. In this paper, we report a modeling of the millimeter-wave polarization of the HL Tau disk with the self-polarization. Dust grains are assumed to be spherical and to have a power-law size distribution. We change the maximum grain size with a fixed dust composition in a fixed disk model to find the grain size to reproduce the observed signature. We find that the direction of the polarization vectors and the polarization degree can be explained with the self-scattering. Moreover, the polarization degree can be explained only if the maximum grain size is ∼150 μm. The obtained grain size from the polarization is different from that which has been previously expected from the spectral index of the dust opacity coefficient (a millimeter or larger) if the emission is optically thin. We discuss that porous dust aggregates may solve the inconsistency of the maximum grain size between the two constraints.

  11. Instrumentation for silicon tracking at the HL-LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00524651; Strandberg, Sara; Garcia-Sciveres, Maurice

    2017-06-14

    In 2027 the Large Hadron Collider (LHC) at CERN will enter a high luminosity phase, deliver- ing 3000 fb 1 over the course of ten years. The High Luminosity LHC (HL-LHC) will increase the instantaneous luminosity delivered by a factor of 5 compared to the current operation pe- riod. This will impose significant technical challenges on all aspects of the ATLAS detector but particularly the Inner Detector, trigger, and data acquisition systems. In addition, many of the components of the Inner Detector are reaching the end of their designed lifetime and will need to be exchanged. As such, the Inner Detector will be entirely replaced by an all silicon tracker, known as the Inner Tracker (ITk). The layout of the Pixel and strip detectors will be optimised for the upgrade and will extend their forward coverage. To reduce the per-pixel hit rate and explore novel techniques for deal- ing with the conditions in HL-LHC, an inter-experiment collaboration called RD53 has been formed. RD53 is tasked with producing a front...

  12. Silicon Strip Detectors for the ATLAS HL-LHC Upgrade

    CERN Document Server

    Miñano, M; The ATLAS collaboration

    2011-01-01

    While the Large Hadron Collider (LHC) at CERN is continuing to deliver an ever-increasing luminosity to the experiments, plans for an upgraded machine called High Luminosity LHC (HL-LHC) are progressing. The upgrade is foreseen to increase the LHC design luminosity up to 5 x 1034 cm-2 s-1. The ATLAS experiment will need to build a new tracker for HL operation, which would cope with the increase in pile-up backgrounds at the higher luminosity. A new generation of extremely radiation hard silicon detectors is being designed. Silicon sensors with sufficient radiation hardness are the subject of an international R&D programme, working on pixel and strip sensors. The efforts presented here concentrate on the innermost strip layers. We have developed a large number of prototype planar detectors produced on p-type wafers in a number of different designs. The irradiated sensors were subsequently tested in order to study the radiation-induced degradation, and determine their performance after irradiation of up to ...

  13. The ATLAS tracker strip detector for HL-LHC

    CERN Document Server

    Cormier, Kyle James Read; The ATLAS collaboration

    2016-01-01

    As part of the ATLAS upgrades for the High Luminsotiy LHC (HL-LHC) the current ATLAS Inner Detector (ID) will be replaced by a new Inner Tracker (ITk). The ITk will consist of two main components: semi-conductor pixels at the innermost radii, and silicon strips covering larger radii out as far as the ATLAS solenoid magnet including the volume currently occupied by the ATLAS Transition Radiation Tracker (TRT). The primary challenges faced by the ITk are the higher planned read out rate of ATLAS, the high density of charged particles in HL-LHC conditions for which tracks need to be resolved, and the corresponding high radiation doses that the detector and electronics will receive. The ITk strips community is currently working on designing and testing all aspects of the sensors, readout, mechanics, cooling and integration to meet these goals and a Technical Design Report is being prepared. This talk is an overview of the strip detector component of the ITk, highlighting the current status and the road ahead.

  14. Analyses of edge plasma characteristics in HL-2A

    Institute of Scientific and Technical Information of China (English)

    Hong Wen-Yu; Yuan Bao-Shan; Liu Li; Ding Xuan-Tong; Yan Long-Wen; Qian Jun; Pan Yu-Dong; Wang En-Yao; Luo Cui-Wen; Xu Zheng-Yu; Pan Li; Li Qiang

    2006-01-01

    The edge plasma characteristics are studied by both a movable array of Mach/Reynolds stress/Langmuir 10-probes in the boundary region and the fixed flush probe arrays on the 4 divertor neutralization plates at the same toroidal crosssection in the HL-2A tokamak. The dependence of the Reynolds stress on poloidal flow in the edge plasma is analysed. The result indicates that the sheared poloidal flow in tokamak plasma can be induced by the radial gradient of Reynolds stress. In the divertor experiments of HL-2A, the profiles of the electron temperature, density and floating potential on divertor plates are measured by the flush probe arrays. The edge electron temperature in divertor configuration is higher than that in limiter configuration. The temperature asymmetry between outer and inner target plates is observed. The result of magnetic surface reconstructed from 18 Mirnov coils signals is presented. Both the particle recycling and the impurity flux in the bulk plasma during divertor discharges are discussed. Neutral gas pressure in divertor chamber, measured by fast ionization gauge during divertor discharge, is given.

  15. Chapter 9: Cryogenics for the HL-LHC

    CERN Document Server

    Claudet, S.

    2015-01-01

    Chapter 9 in High-Luminosity Large Hadron Collider (HL-LHC) : Preliminary Design Report. The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity (rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology beyond its present limits. Amon...

  16. Hydraulic Yaw System

    DEFF Research Database (Denmark)

    Stubkier, Søren; Pedersen, Henrik C.; Mørkholt, M.

    As wind turbines increase in size, combined with increased lifetime demands, new methods for load reduction needs to be examined. One method is to make the yaw system of the turbine soft/flexible and hereby dampen the loads to the system, which is the focus of the current paper. By utilizing...... the HAWC2 aeroelastic code and an extended model of the NREL 5MW turbine combined with a simplified linear model of the turbine, the parameters of the soft yaw system are optimized to reduce loading in critical components. Results shows that a significant reduction in fatigue and extreme loads to the yaw...... system and rotor shaft when utilizing the soft yaw drive concept compared to the original stiff yaw system. The physical demands of the hydraulic yaw system are furthermore examined for a life time of 20 years. Based on the extrapolated loads, the duty cycles show that it is possible to construct...

  17. Electro Hydraulic Hitch Control

    DEFF Research Database (Denmark)

    Hansen, M. R.; Andersen, T. O.; Nielsen, B.

    2003-01-01

    system for agricultural applications and driving for transportation. During tranport phases, the lack of suspension causes the vehicle to bounce and pitch, and makes it difficalt to control. Many systems have been proposed to cope with the oscillatory behavior, and different solutions exist. Common......This paper present and discusses R&D results on electro hydraulic hitch control for off-road vehicle, in particular active damping of oscillation occuring on tractors. The research deals with analysis and control of the oscillations occuring on tractors which are design without any susspection...... for most of the systems are that they operate on the hydrailc actuators generally providing the motive forces for moving the implement and/or attachment, typically a plough. The basic idea and physical working principle are to use the implement, moveable relative to the vehicle, as a damper mass. The paper...

  18. Coriolis effects enhance lift on revolving wings.

    Science.gov (United States)

    Jardin, T; David, L

    2015-03-01

    At high angles of attack, an aircraft wing stalls. This dreaded event is characterized by the development of a leading edge vortex on the upper surface of the wing, followed by its shedding which causes a drastic drop in the aerodynamic lift. At similar angles of attack, the leading edge vortex on an insect wing or an autorotating seed membrane remains robustly attached, ensuring high sustained lift. What are the mechanisms responsible for both leading edge vortex attachment and high lift generation on revolving wings? We review the three main hypotheses that attempt to explain this specificity and, using direct numerical simulations of the Navier-Stokes equations, we show that the latter originates in Coriolis effects.

  19. Lifted Inference for Relational Continuous Models

    CERN Document Server

    Choi, Jaesik; Hill, David J

    2012-01-01

    Relational Continuous Models (RCMs) represent joint probability densities over attributes of objects, when the attributes have continuous domains. With relational representations, they can model joint probability distributions over large numbers of variables compactly in a natural way. This paper presents a new exact lifted inference algorithm for RCMs, thus it scales up to large models of real world applications. The algorithm applies to Relational Pairwise Models which are (relational) products of potentials of arity 2. Our algorithm is unique in two ways. First, it substantially improves the efficiency of lifted inference with variables of continuous domains. When a relational model has Gaussian potentials, it takes only linear-time compared to cubic time of previous methods. Second, it is the first exact inference algorithm which handles RCMs in a lifted way. The algorithm is illustrated over an example from econometrics. Experimental results show that our algorithm outperforms both a groundlevel inferenc...

  20. Fuel Cell Hydroge Manifold for Lift Trucks

    DEFF Research Database (Denmark)

    Hosseinzadeh, Elham

    Reducing CO2 emissions are getting more attention because of global warming. The transport sector which is responsible for a significant amount of emissions is going to reduce them due to new and upcoming regulations. Using fuel cells may be one way to help to reduce the emissions from this sector....... Battery driven lift trucks are being used more and more in different companies to reduce their emissions. However, battery driven lift trucks need long time to recharge and may be out of work for a long time. Fuel cell driven lift trucks diminish this problem and are therefore getting more attention....... The most common type of fuel cell used for automotive applications is PEM fuel cell. They are known for their high efficiency, low emissions and high reliability. However, lack of a hydrogen infrastructure, cost and durability of the stack is considered the biggest obstacles to the introduction of fuel...

  1. Design and Development of Attachment for Hydraulic Stacker

    Directory of Open Access Journals (Sweden)

    S.H. Gawande

    2010-05-01

    Full Text Available The main purpose of this paper is to develop an Attachment which will enable the lateral movement of the manufacturing Dies by mounting it on the forks of any Hydraulic Stacker or Fork Lift. The Attachmentmanufactured is unique because it can be attached or mounted on any hydraulic stalker in the One Tonne range. The attachment is a combination of two separate bed of rollers, a lead screw, a gear mechanism and a moving frame which enables the hydraulic stacker to easily load or unload Dies upto the range of one tonne, in and out of Machine Presses and Storage Racks which reduces material handling time and cost, manual effort and increases safety. The developed attachment in this work can also be easily detached and kept aside when not in use, so that the stacker can be used for regular purposes in the logistics department. The detail design, fabrication and testing work is carried out at A.V.M Seating Systems Ltd, Pune-26.

  2. Asymmetric Gepner Models II. Heterotic Weight Lifting

    CERN Document Server

    Gato-Rivera, B

    2010-01-01

    A systematic study of "lifted" Gepner models is presented. Lifted Gepner models are obtained from standard Gepner models by replacing one of the N=2 building blocks and the $E_8$ factor by a modular isomorphic $N=0$ model on the bosonic side of the heterotic string. The main result is that after this change three family models occur abundantly, in sharp contrast to ordinary Gepner models. In particular, more than 250 new and unrelated moduli spaces of three family models are identified. We discuss the occurrence of fractionally charged particles in these spectra.

  3. Fuel Cell Hydroge Manifold for Lift Trucks

    OpenAIRE

    Hosseinzadeh, Elham; Rokni, Masoud; Elmegaard, Brian

    2012-01-01

    Reducing CO2 emissions are getting more attention because of global warming. The transport sector which is responsible for a significant amount of emissions is going to reduce them due to new and upcoming regulations. Using fuel cells may be one way to help to reduce the emissions from this sector. Battery driven lift trucks are being used more and more in different companies to reduce their emissions. However, battery driven lift trucks need long time to recharge and may be out of work for a...

  4. Soccer ball lift coefficients via trajectory analysis

    Energy Technology Data Exchange (ETDEWEB)

    Goff, John Eric [Department of Physics, Lynchburg College, Lynchburg, VA 24501 (United States); Carre, Matt J, E-mail: goff@lynchburg.ed [Department of Mechanical Engineering, University of Sheffield, Sheffield S1 3JD (United Kingdom)

    2010-07-15

    We performed experiments in which a soccer ball was launched from a machine while two high-speed cameras recorded portions of the trajectory. Using the trajectory data and published drag coefficients, we extracted lift coefficients for a soccer ball. We determined lift coefficients for a wide range of spin parameters, including several spin parameters that have not been obtained by today's wind tunnels. Our trajectory analysis technique is not only a valuable tool for professional sports scientists, it is also accessible to students with a background in undergraduate-level classical mechanics.

  5. Asymmetric Gepner models II. Heterotic weight lifting

    Energy Technology Data Exchange (ETDEWEB)

    Gato-Rivera, B. [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands); Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain); Schellekens, A.N., E-mail: t58@nikhef.n [NIKHEF Theory Group, Kruislaan 409, 1098 SJ Amsterdam (Netherlands); Instituto de Fisica Fundamental, CSIC, Serrano 123, Madrid 28006 (Spain); IMAPP, Radboud Universiteit, Nijmegen (Netherlands)

    2011-05-21

    A systematic study of 'lifted' Gepner models is presented. Lifted Gepner models are obtained from standard Gepner models by replacing one of the N=2 building blocks and the E{sub 8} factor by a modular isomorphic N=0 model on the bosonic side of the heterotic string. The main result is that after this change three family models occur abundantly, in sharp contrast to ordinary Gepner models. In particular, more than 250 new and unrelated moduli spaces of three family models are identified. We discuss the occurrence of fractionally charged particles in these spectra.

  6. Vaginal pressure during lifting, floor exercises, jogging, and use of hydraulic exercise machines.

    Science.gov (United States)

    O'Dell, Katharine K; Morse, Abraham N; Crawford, Sybil L; Howard, Allison

    2007-12-01

    We recorded vaginal pressure in 12 women without risk factors for prolapse during two activity and exercise sessions, compared exercise and cough pressure, and evaluated method reproducibility and patterns of relative pressure. Portable urodynamic equipment, repeated measures descriptive design, and purposeful sampling were used with nonparametric analysis and visual comparison of pressure graphs. Mean participant age was 31.1 years (range 20-51), and mean body mass index was 22.7 (range 18.5-29.3). Mean pressures (in cm H(2)O): cough, 98.0 (48.0-133.7); standing, 24.0 (15.9-28.5); supine exercise, 34.0 (6.3-91.9); exercise machines, 37.0 (20.3-182.3). Repeated measures correlations for selected measures ranged from 0.66 (p

  7. [Drug resistance reversal of HL-60/ADR cells by simultaneous suppression of XIAP and MRP].

    Science.gov (United States)

    Wang, Xiao-Fang; Wang, Chun; Qin, You-Wen; Yan, Shi-Ke; Gao, Yan-Rong

    2006-12-01

    This study was purposed to explore the mechanisms of drug resistance of HL-60/ADR cells and to compare the reversal drug-resistance effects of antisense oligonucleotides (AS ODN) of XIAP (X-linked inhibitor of apoptosis protein) and AS ODNs of MRP (multidrug resistance-associated protein) by use alone or in combination. Reverse transcription-PCR and Western blot were applied to detect the expression of XIAP, BCL-2, MRP and MDR1 in mRNA and protein levels of HL-60 cells and HL-60/ADR cells, respectively. Fully phosphorothioated AS ODN of XIAP and MRP was delivered into HL-60/ADR cells with Lipofectamine 2000 in the form of liposome-ODN complexes alone or in combination. CCK-8 cell viability assay was used to determine the effect of AS ODN of XIAP and MRP used alone or in combination on the chemotherapy sensitivity of HL-60/ADR cells to daunorubicin (DNR). Reverse transcription-PCR and Western blot were applied to examine the changes of XIAP, MRP in mRNA and protein levels respectively. The results showed that MRP and XIAP were both significantly higher in HL-60/ADR cells than those in HL-60 cells. AS ODN of XIAP and MRP down-regulated the expression of XIAP and MRP in HL-60/ADR cells and increased the sensitivity of HL-60/ADR cells to DNR, respectively. AS ODN of XIAP + MRP did not enhance the inhibition expression of XIAP in HL-60/ADR cells but increased the sensitivity of HL-60/ADR cells to DNR significantly as compared with AS ODN of XIAP (P MRP did not increase the concentration of DNR nor enhanced the inhibition expression of MRP in HL-60/ADR cells but increased the sensitivity of HL-60/ADR cells to DNR significantly (P MRP. It is concluded that both XIAP and MRP may be involved in the drug resistance mechanisms of HL-60/ADR cells. Drug-resistance of HL-60/ADR cells can be reversed significantly when antisense oligonucleotides of XIAP and MRP were used in combination.

  8. Economic Recovery of Oil Trapped at Fan Margins Using High Angle Wells and Multiple Hydraulic Fractures

    Energy Technology Data Exchange (ETDEWEB)

    Mike L. Laue

    1997-05-30

    The distal fan margin in the northeast portion of the Yowlumne field contains significant reserves but is not economical to develop using vertical wells. Numerous interbedded shales and deteriorating rock properties limit producibility. In addition, extreme depths (13,000 ft) present a challenging environment for hydraulic fracturing and artificial lift. Lastly, a mature waterflood increases risk because of the uncertainty with size and location of flood fronts. This project attempts to demonstrate the effectiveness of exploiting the distal fan margin of this slope-basin clastic reservoir through the use of a high-angle well completed with multiple hydraulic-fracture treatments. The combination of a high-angle (or horizontal) well and hydraulic fracturing will allow greater pay exposure than can be achieved with conventional vertical wells while maintaining vertical communication between thin interbedded layers and the wellbore. The equivalent production rate and reserves of three vertical wells are anticipated at one-half to two-thirds the cost.

  9. Hydraulic conductivity of compacted zeolites.

    Science.gov (United States)

    Oren, A Hakan; Ozdamar, Tuğçe

    2013-06-01

    Hydraulic conductivities of compacted zeolites were investigated as a function of compaction water content and zeolite particle size. Initially, the compaction characteristics of zeolites were determined. The compaction test results showed that maximum dry unit weight (γ(dmax)) of fine zeolite was greater than that of granular zeolites. The γ(dmax) of compacted zeolites was between 1.01 and 1.17 Mg m(-3) and optimum water content (w(opt)) was between 38% and 53%. Regardless of zeolite particle size, compacted zeolites had low γ(dmax) and high w(opt) when compared with compacted natural soils. Then, hydraulic conductivity tests were run on compacted zeolites. The hydraulic conductivity values were within the range of 2.0 × 10(-3) cm s(-1) to 1.1 × 10(-7) cm s(-1). Hydraulic conductivity of all compacted zeolites decreased almost 50 times as the water content increased. It is noteworthy that hydraulic conductivity of compacted zeolite was strongly dependent on the zeolite particle size. The hydraulic conductivity decreased almost three orders of magnitude up to 39% fine content; then, it remained almost unchanged beyond 39%. Only one report was found in the literature on the hydraulic conductivity of compacted zeolite, which is in agreement with the findings of this study.

  10. A high resolution coupled hydrologic-hydraulic model (HiResFlood-UCI) for flash flood modeling

    Science.gov (United States)

    Nguyen, Phu; Thorstensen, Andrea; Sorooshian, Soroosh; Hsu, Kuolin; AghaKouchak, Amir; Sanders, Brett; Koren, Victor; Cui, Zhengtao; Smith, Michael

    2016-10-01

    HiResFlood-UCI was developed by coupling the NWS's hydrologic model (HL-RDHM) with the hydraulic model (BreZo) for flash flood modeling at decameter resolutions. The coupled model uses HL-RDHM as a rainfall-runoff generator and replaces the routing scheme of HL-RDHM with the 2D hydraulic model (BreZo) in order to predict localized flood depths and velocities. A semi-automated technique of unstructured mesh generation was developed to cluster an adequate density of computational cells along river channels such that numerical errors are negligible compared with other sources of error, while ensuring that computational costs of the hydraulic model are kept to a bare minimum. HiResFlood-UCI was implemented for a watershed (ELDO2) in the DMIP2 experiment domain in Oklahoma. Using synthetic precipitation input, the model was tested for various components including HL-RDHM parameters (a priori versus calibrated), channel and floodplain Manning n values, DEM resolution (10 m versus 30 m) and computation mesh resolution (10 m+ versus 30 m+). Simulations with calibrated versus a priori parameters of HL-RDHM show that HiResFlood-UCI produces reasonable results with the a priori parameters from NWS. Sensitivities to hydraulic model resistance parameters, mesh resolution and DEM resolution are also identified, pointing to the importance of model calibration and validation for accurate prediction of localized flood intensities. HiResFlood-UCI performance was examined using 6 measured precipitation events as model input for model calibration and validation of the streamflow at the outlet. The Nash-Sutcliffe Efficiency (NSE) obtained ranges from 0.588 to 0.905. The model was also validated for the flooded map using USGS observed water level at an interior point. The predicted flood stage error is 0.82 m or less, based on a comparison to measured stage. Validation of stage and discharge predictions builds confidence in model predictions of flood extent and localized velocities

  11. Hydraulic Actuators with Autonomous Hydraulic Supply for the Mainline Aircrafts

    Directory of Open Access Journals (Sweden)

    I. S. Shumilov

    2014-01-01

    Full Text Available Applied in the aircraft control systems, hydraulic servo actuators with autonomous hydraulic supply, so-called, hydraulic actuators of integrated configuration, i.e. combination of a source of hydraulic power and its load in the single unit, are aimed at increasing control system reliability both owing to elimination of the pipelines connecting the actuator to the hydraulic supply source, and owing to avoidance of influence of other loads failure on the actuator operability. Their purpose is also to raise control system survivability by eliminating the long pipeline communications and their replacing for the electro-conductive power supply system, thus reducing the vulnerability of systems. The main reason for a delayed application of the hydraulic actuators in the cutting-edge aircrafts was that such aircrafts require hydraulic actuators of considerably higher power with considerable heat releases, which caused an unacceptable overheat of the hydraulic actuators. Positive and negative sides of the hydraulic actuators, their alternative options of increased reliability and survivability, local hydraulic systems as an advanced alternative to independent hydraulic actuators are considered.Now to use hydraulic actuators in mainline aircrafts is inexpedient since there are the unfairly large number of the problems reducing, first and last, safety of flights, with no essential weight and operational advantages. Still works to create competitive hydraulic actuators ought to be continued.Application of local hydraulic systems (LHS will allow us to reduce length of pressure head and drain pipelines and mass of pipelines, as well as to raise their general fail-safety and survivability. Application of the LHS principle will allow us to use a majority of steering drive advantages. It is necessary to allocate especially the following:- ease of meeting requirements for the non-local spread of the engine weight;- essentially reducing length and weight of

  12. Hydraulic conductivity of organomodified soil

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, R.B.; Grant, J.M.; Voice, T.C.; Rakhshandehroo, G.; Xu, S.; Boyd, S.A. [Michigan State Univ., East Lansing, MI (United States)

    1995-11-01

    The effects of organomodification on soil hydraulic conductivity were investigated. Hydraulic conductivity and porosity of treated and untreated samples of a sandy loam were measured as a function of effective stress. Batch treatment with hexadecyltrimethyl ammonium (HDTMA) and dry packing produced organomodified samples that were 79% less conducive than untreated samples prior to loading. Treated samples lost less hydraulic conductivity as a result of loading than untreated samples so that treated samples had higher conductivity at high loads. Observed differences in conductivity are explained in terms of the role of the treated and untreated clay in controlling initial effective pore size and its change during consolidation.

  13. Formal methods impact on ANSI standard HL7/IM: filling gaps in MSC theory

    NARCIS (Netherlands)

    W. Wesselink; N. Goga (Nicolae); A.J. Mooij (Arjan); R. Spronk

    2005-01-01

    htmlabstractHealth level seven (HL7) is an ANSI standard that provides a comprehensive framework for electronic health information. The most-widely used HL7 specification is called infrastructure management, which facilitates health-care applications to exchange key sets of clinical and

  14. Formal methods impact on ANSI standard HL7/IM: filling gaps in MSC theory

    NARCIS (Netherlands)

    W. Wesselink; N. Goga (Nicolae); A.J. Mooij (Arjan); R. Spronk

    2005-01-01

    htmlabstractHealth level seven (HL7) is an ANSI standard that provides a comprehensive framework for electronic health information. The most-widely used HL7 specification is called infrastructure management, which facilitates health-care applications to exchange key sets of clinical and administrati

  15. A Quantitative Approach to Investigating Spanish HL Speakers' Characteristics and Motivation: A Preliminary Study

    Science.gov (United States)

    Yanguas, Inigo

    2010-01-01

    The present preliminary study empirically investigated Spanish heritage language (HL) speakers in Spanish for native speakers (SNS) college courses. It focused on their attitudes and motivation to improve their HL and on their varying linguistic competences in that language. A well-established second language acquisition (SLA) motivational model…

  16. HL7 template model and EN/ISO 13606 archetype object model - a comparison.

    Science.gov (United States)

    Bointner, Karl; Duftschmid, Georg

    2009-01-01

    HL7 Templates and EN/ISO 13606 Archetypes are essential components for a semantically interoperable exchange of electronic health record (EHR) data. In this article the underlying models from which Templates and Archetypes are instantiated, namely the HL7 Template Model and the EN/ISO 13606 Archetype Object Model will be compared to identify discrepancies and analogies.

  17. MG132 Induced Apoptosis Pathway in HL-60 Cells and Impact of Allogeneic Mixed Lymphocyte Reaction

    Institute of Scientific and Technical Information of China (English)

    Yong-ming Zhou; Wei Guo; Hao Zhou; Jin-hua Zhang; Zhi-ping Liu; Mei-xia Yu

    2009-01-01

    Objective: To investigate the proteasome inhibitor MG132-induced apoptosis pathway in HL-60 cells and the role of allogeneic mixed lymphocyte reaction.Methods: Cell apoptosis was analyzed by flow cytometry. The expressions of p21 protein, p27 protein and p53 protein in HL-60 cells treated with MG132 were measured by Western blot. The proliferation of, peripheral blood mononuclear cells (PBMNCs) after treatment with 75 Gy irradiated HL-60 cells treated with MG132 was measured with CCK-8.Results: High-dose MG132 induced apoptosis in HL-60 cells. No significant change was observed in MG132-induced apoptosis after inhibiting caspase-8 and caspase-9 pathway. The expressions of p21 protein and p27 protein increased in MG132-induced apoptosis. HL-60 cells treated with low-dose MG132 improved the proliferation of PBMNCs from healthy volunteers.Conclusion: High-dose MG132 induced apoptosis and directly killed HL-60 cells. MG132 induced apoptosis in a caspase-8- and caspase-9-independent pathway. p21 protein and p27 protein were involved in MG132-induced apoptosis in HL-60 cells. HL-60 cells treated with Low-dose MG132 improved the effect of promoting the proliferation of PBMNCs from healthy volunteers.

  18. [Influence of TIEG1 on apoptosis of HL-60 cells and expression of Bcl-2/Bax].

    Science.gov (United States)

    Yao, Kun; Yang, Ying; Hu, Rong; Miao, Miao; Liao, Ai-Jun; Yang, Wei; Liu, Zhuo-Gang

    2013-06-01

    This study was aimed to investigate the influence of TIEG1 on apoptosis of HL-60 cells and the expression of Bcl-2/Bax. Different concentration of TIEG1 were used to treat HL-60 cells, the cell growth inhibition rate was detected by MTT method. After treating HL-60 cells with 12.03 ng/ml TIEG1, cell apoptosis was detected with flow cytometry. Bcl-2 and Bax was detected with RT-PCR. The results showed that TIEG1 had inhibitory effect on HL-60 cell proliferation, and in time-and dose-dependent manners. The more obvious inhibitory effect was observed in HL-60 cells treated with TIEG1 of 12.03 ng/ml. During the course of cell apoptosis, Bax expression increased, but Bcl-2 expression decreased (P HL-60 cell proliferation and induces apoptosis in time and dose-dependent manners. During the course of HL-60 cells apoptosis induced by TIEG1, Bcl-2/Bax are associated with HL-60 cell apoptosis induced by TIEG1.

  19. [Human umbilical cord mesenchymal stem cells reduce the sensitivity of HL-60 cells to cytarabine].

    Science.gov (United States)

    Cui, Jun-Jie; Chi, Ying; Du, Wen-Jing; Yang, Shao-Guang; Li, Xue; Chen, Fang; Ma, Feng-Xia; Lu, Shi-Hong; Han, Zhong-Chao

    2013-06-01

    This study was purposed to investigate the impact of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) on the sensitivity of HL-60 cells to therapeutic drugs so as to provide more information for exploring the regulatory effect of hUC-MSC on leukemia cells. Transwell and direct co-culture systems of HL-60 and hUC-MSC were established. The apoptosis and cell cycle of HL-60 cells were detected by flow cytometry. RT-PCR and Western blot were used to detect the mRNA and protein levels of Caspase 3, respectively. The results showed that the apoptosis of HL-60 induced by cytarabine (Ara-C) decreased significantly after direct co-cultured with hUC-MSC cycle mRNA (P HL-60 cells were arrested at G0/G1 phase and did not enter into S phase (P HL-60 cells were reduced (P HL-60 from Arc-C induced apoptosis through regulating the cell cycle and down-regulating expression of Caspase 3 in HL-60 cells. In addition, this effect is caused by the soluble factors from hUC-MSC.

  20. Diesel exhaust particle-induced cell death of human leukemic promyelocytic cells HL-60 and their variant cells HL-NR6.

    Science.gov (United States)

    Matsuo, M; Uenishi, R; Shimada, T; Yamanaka, S; Yabuki, M; Utsumi, K; Sagai, M

    2001-04-01

    The cytotoxicity of diesel exhaust particles (DEPs) toward human leukemic promyelocytic cells HL-60 was examined. DEPs were toxic and cytotoxicity increased in a dose-dependent manner. All cells died with 750 microg/ml DEPs in culture media. Apoptosis occurred in HL-60 cells exposed to DEPs. The cytotoxicity of DEP extracts with organic solvents was much lower than those of DEPs and organic solvent-washed residual DEPs. HL-NR6 cells, an HL-60 variant cell line, having higher superoxide dismutase and catalase activities than HL-60 cells, were more resistant to DEP cytotoxicity. When preincubated with the fluorescent probe diacetoxymethyl 6-carboxy-2',7'-dichlorodihydrofluorescinate diacetate and then exposed to DEPs, HL-60 cells emitted green fluorescence under blue illumination, indicating that reactive oxygen species were generated within the cells. The DEP cytotoxicity correlated inversely with the cellular concentration of reduced glutathione (GSH), which had been attenuated with L-buthionine-(R,S)-sulfoximine, a gamma-glutamylcysteine synthetase inhibitor, and was lowered with ethyl reduced glutathionate, a GSH carrier across biomembranes. Further, DEPs themselves decreased the cellular concentration of GSH in a dose-dependent manner. The alpha-tocopherol model compound 2,2,5,7,8-pentamethylchroman-6-ol decreased DEP cytotoxicity, while alpha-tocopherol had no effect. In addition, quinacrine, an endocytosis inhibitor, decreased DEP cytotoxicity. These results show that DEPs are cytotoxic and suggest that the cytotoxicity results from generation of reactive oxygen species by DEPs which have been incorporated into cells.

  1. Complications of lower blepharoplasty and midface lifting.

    Science.gov (United States)

    Schwarcz, Robert M; Kotlus, Brett

    2015-01-01

    Lower eyelid blepharoplasty and midface lifting share a complex anatomy, which should be mastered before attempting these types of surgeries. In recent years, there have been significant contributions to rejuvenating this area. A thorough understanding of the rejuvenative approaches and their outcomes is imperative. Thus, the problem must be preoperatively evaluated to offer the appropriate technique and minimize complications.

  2. Leading-Edge Vortex lifts swifts

    NARCIS (Netherlands)

    Videler, JJ; Stamhuis, EJ; Povel, GDE

    2004-01-01

    The current understanding of how birds fly must be revised, because birds use their hand-wings in an unconventional way to generate lift and drag. Physical models of a common swift wing in gliding posture with a 60degrees sweep of the sharp hand-wing leading edge were tested in a water tunnel. Inter

  3. Lifts of projective congruence groups, II

    DEFF Research Database (Denmark)

    Kiming, Ian

    2014-01-01

    We continue and complete our previous paper ``Lifts of projective congruence groups'' concerning the question of whether there exist noncongruence subgroups of  that are projectively equivalent to one of the groups  or . A complete answer to this question is obtained: In case of  such noncongruence...

  4. Measuring Lift with the Wright Airfoils

    Science.gov (United States)

    Heavers, Richard M.; Soleymanloo, Arianne

    2011-01-01

    In this laboratory or demonstration exercise, we mount a small airfoil with its long axis vertical at one end of a nearly frictionless rotating platform. Air from a leaf blower produces a sidewise lift force L on the airfoil and a drag force D in the direction of the air flow (Fig. 1). The rotating platform is kept in equilibrium by adding weights…

  5. Redheffer representations and relaxed commutant lifting

    NARCIS (Netherlands)

    ter Horst, S.

    2011-01-01

    It is well known that the solutions of a (relaxed) commutant lifting problem can be described via a linear fractional representation of the Redheffer type. The coefficients of such Redheffer representations are analytic operator-valued functions defined on the unit disc D of the complex plane. In th

  6. Image Compression using Space Adaptive Lifting Scheme

    Directory of Open Access Journals (Sweden)

    Ramu Satyabama

    2011-01-01

    Full Text Available Problem statement: Digital images play an important role both in daily life applications as well as in areas of research and technology. Due to the increasing traffic caused by multimedia information and digitized form of representation of images; image compression has become a necessity. Approach: Wavelet transform has demonstrated excellent image compression performance. New algorithms based on Lifting style implementation of wavelet transforms have been presented in this study. Adaptively is introduced in lifting by choosing the prediction operator based on the local properties of the image. The prediction filters are chosen based on the edge detection and the relative local variance. In regions where the image is locally smooth, we use higher order predictors and near edges we reduce the order and thus the length of the predictor. Results: We have applied the adaptive prediction algorithms to test images. The original image is transformed using adaptive lifting based wavelet transform and it is compressed using Set Partitioning In Hierarchical Tree algorithm (SPIHT and the performance is compared with the popular 9/7 wavelet transform. The performance metric Peak Signal to Noise Ratio (PSNR for the reconstructed image is computed. Conclusion: The proposed adaptive algorithms give better performance than 9/7 wavelet, the most popular wavelet transforms. Lifting allows us to incorporate adaptivity and nonlinear operators into the transform. The proposed methods efficiently represent the edges and appear promising for image compression. The proposed adaptive methods reduce edge artifacts and ringing and give improved PSNR for edge dominated images.

  7. Soft sensing for gas-lift wells

    NARCIS (Netherlands)

    Bloemen, H.H.J.; Belfroid, S.P.C.; Sturm, W.L.; Verhelst, F.J.P.C.M.G.

    2006-01-01

    This paper considers the use of extended Kalman filtering as a soft-sensing technique for gas lift wells. This technique is deployed for the estimation of dynamic variables that are not directly measured. Possible applications are the estimation of flow rates from surface and downhole pressure measu

  8. Innovative Alternatives to Lifting Overturned Military Vehicles

    Science.gov (United States)

    2014-04-25

    objects. For instance, Mine -Resistant Ambush Protected (MRAP) vehicles, which can weigh up to 55,000 lbs, have in the past overturned, trapping people...through long, small wires, and gives the user great control over the lift. The motors are powered by high performance 6.0 amp-hour lithium

  9. Computational Fluid Dynamic Analyses for the High-Lift Common Research Model Using the USM3D and FUN3D Flow Solvers

    Science.gov (United States)

    Rivers, Melissa; Hunter, Craig; Vatsa, Veer

    2017-01-01

    Two Navier-Stokes codes were used to compute flow over the High-Lift Common Research Model (HL-CRM) in preparation for a wind tunnel test to be performed at the NASA Langley Research Center 14-by-22-Foot Subsonic Tunnel in fiscal year 2018. Both flight and wind tunnel conditions were simulated by the two codes at set Mach numbers and Reynolds numbers over a full angle-of-attack range for three configurations: cruise, landing and takeoff. Force curves, drag polars and surface pressure contour comparisons are shown for the two codes. The lift and drag curves compare well for the cruise configuration up to 10deg angle of attack but not as well for the other two configurations. The drag polars compare reasonably well for all three configurations. The surface pressure contours compare well for some of the conditions modeled but not as well for others.

  10. Integration of IEEE 1451 and HL7 Exchanging Information for Patients’ Sensor Data

    Science.gov (United States)

    Lim, Suyoung; Ahn, Jinsoo; Nah, Jiyoung; Kim, Namhyun

    2009-01-01

    HL7 (Health Level 7) is a standard developed for exchanging incompatible healthcare information generated from programs or devices among heterogenous medical information systems. At present, HL7 is growing as a global standard. However, the HL7 standard does not support effective methods for treating data from various medical sensors, especially from mobile sensors. As ubiquitous systems are growing, HL7 must communicate with various medical transducers. In the area of sensor fields, IEEE 1451 is a group of standards for controlling transducers and for communicating data from/to various transducers. In this paper, we present the possibility of interoperability between the two standards, i.e., HL7 and IEEE 1451. After we present a method to integrate them and show the preliminary results of this approach. PMID:20703604

  11. Integration of IEEE 1451 and HL7 exchanging information for patients' sensor data.

    Science.gov (United States)

    Kim, Wooshik; Lim, Suyoung; Ahn, Jinsoo; Nah, Jiyoung; Kim, Namhyun

    2010-12-01

    HL7 (Health Level 7) is a standard developed for exchanging incompatible healthcare information generated from programs or devices among heterogenous medical information systems. At present, HL7 is growing as a global standard. However, the HL7 standard does not support effective methods for treating data from various medical sensors, especially from mobile sensors. As ubiquitous systems are growing, HL7 must communicate with various medical transducers. In the area of sensor fields, IEEE 1451 is a group of standards for controlling transducers and for communicating data from/to various transducers. In this paper, we present the possibility of interoperability between the two standards, i.e., HL7 and IEEE 1451. After we present a method to integrate them and show the preliminary results of this approach.

  12. Upgrades of the CMS outer tracker for HL-LHC

    CERN Document Server

    Sguazzoni, Giacomo

    2015-01-01

    The LHC machine is planning an upgrade program which will smoothly bring the luminosity up to or above $5\\times 10^{34}$cm$^{-2}$s$^{-1}$ sometimes after 2020, to possibly reach an integrated luminosity of 3000fb$^{-1}$ at the end of that decade. In this ultimate scenario, called Phase-2, when LHC will reach the High Luminosity (HL-LHC) phase, CMS will need a completely new Tracker detector, in order to fully exploit the high-demanding operating conditions and the delivered luminosity. The new Tracker should have also trigger capabilities. To achieve such goals, R and D activities are ongoing to explore options and develop solutions that would allow including tracking information at Level-1. The design choices for the CMS Outer Tracker upgrades are discussed along with some highlights of the R and D activities.

  13. Injection Protection Upgrade for the HL-LHC

    CERN Document Server

    AUTHOR|(CDS)2067108; Biancacci, Nicolo; Bracco, Chiara; Frasciello, Oscar; Gentini, Luca; Goddard, Brennan; Lechner, Anton; Maciariello, Fausto; Perillo Marcone, Antonio; Salvant, Benoit; Shetty, Nikhil Vittal; Steele, Genevieve; Velotti, Francesco; Zobov, Mikhail

    2015-01-01

    The injector complex of the LHC is undergoing important changes in the light of the LIU project to provide brighter beams to the LHC. For this reason and as part of the High Luminosity LHC project the injection protection system of the LHC will be upgraded in the Long Shutdown 2 (2018 - 2019) to be able to protect downstream elements against injection failures with the high brightness, high intensity HL-LHC beams. The upgraded LHC injection protection system will consist of a segmented injection protection absorber TDIS, and auxiliary collimators and masks. The layout modifications are described, and the machine element protection and absorber jaw robustness studies are presented for the new systems.

  14. CMS Pixel Detector design for HL-LHC

    CERN Document Server

    Migliore, Ernesto

    2016-01-01

    The LHC machine is planning an upgrade program which will smoothly bring the luminosity to about 7.5$\\times$10$^{34}$cm$^{-2}$s$^{-1}$ in 2028, to possibly reach an integrated luminosity of 3000 fb$^{-1}$ by the end of 2037. This High Luminosity scenario, HL-LHC, will present new challenges in higher data rates and increased radiation.In order to maintain its physics reach the CMS Collaboration has undertaken a preparation program of the detector known as Phase-2 upgrade. The CMS Phase-2 Pixel upgrade will require a high bandwidth readout system and high radiation tolerance for sensors and on-detector ASICs. Several technologies for the upgrade sensors are being studied. Serial powering schemes are under consideration to accommodate significant constraints on the system. These prospective designs, as well as new layout geometries that include very forward pixel discs, will be presented together with performance estimations.

  15. Preliminary Analysis of HL-2A Global Energy Confinement

    Institute of Scientific and Technical Information of China (English)

    DONG Chunfeng; CUI Zhengying; JI Xiaoquan; ZHOU Hangyu; FENG Beibin; SUN Hongjuan; LI Yonggao; YANG Qingwei

    2009-01-01

    Energy confinement time taken from 135 discharges of the 2006 campaign in HL-2A is studied.The.data obtained from the measurements are verified by comparing diamagnetic energy with the electronic kinetic energy calculated from both the electron temperature and density profiles.Two data sets for supporting the ITER L-Mode confinement database are generated from the 2006 campaign.The dependence of гE on the line-averaged electron density during ohmic phases is analysed.The comparison of гE in electron cyclotron resonance heating(ECRH) plasma as well as the existing ITER L-mode scalings is made.The results show that the energy confinement time is consistent with the ITER L-mode scalings.

  16. CMS Pixel Detector design for HL-LHC

    Science.gov (United States)

    Migliore, E.

    2016-12-01

    The LHC machine is planning an upgrade program which will smoothly bring the luminosity to about 7.5×1034cm-2s-1 in 2028, to possibly reach an integrated luminosity of 3000 fb-1 by the end of 2037. This High Luminosity scenario, HL-LHC, will present new challenges in higher data rates and increased radiation. In order to maintain its physics reach the CMS collaboration has undertaken a preparation program of the detector known as Phase-2 upgrade. The CMS Phase-2 Pixel upgrade will require a high bandwidth readout system and high radiation tolerance for sensors and on-detector ASICs. Several technologies for the upgrade sensors are being studied. Serial powering schemes are under consideration to accommodate significant constraints on the system. These prospective designs, as well as new layout geometries that include very forward pixel discs, will be presented together with performance estimation.

  17. Lift estimation of Half-Rotating Wing in hovering flight

    Science.gov (United States)

    Wang, X. Y.; Dong, Y. P.; Qiu, Z. Z.; Zhang, Y. Q.; Shan, J. H.

    2016-11-01

    Half-Rotating Wing (HRW) is a new kind of flapping wing system with rotating flapping instead of oscillating flapping. Estimating approach of hovering lift which generated in hovering flight was important theoretical foundation to design aircraft using HRW. The working principle of HRW based on Half-Rotating Mechanism (HRM) was firstly introduced in this paper. Generating process of lift by HRW was also given. The calculating models of two lift mechanisms for HRW, including Lift of Flow Around Wing (LFAW) and Lift of Flow Dragging Wing (LFDW), were respectively established. The lift estimating model of HRW was further deduced, by which hovering lift for HRW with different angular velocity could be calculated. Case study using XFLOW software simulation indicates that the above estimating method was effective and feasible to predict roughly the hovering lift for a new HRW system.

  18. Hybrid Aircraft for Heavy Lift / High Speed Strategic Mobility

    Science.gov (United States)

    2011-04-01

    engines only need to move the airship , not lift it. AU/ACSC/KRISTOF/AY11 12 Figure 6: Aerodynamic Lift (Source: Wikipedia.org at http...4 Early Modern Military Airship Operations ................................................................................. 4 A...10 II: Airship Basics

  19. HYDRAULICS, ATHENS COUNTY, OHIO, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulic data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  20. HYDRAULICS, JACKSON COUNTY, KENTUCKY, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulic data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  1. HYDRAULICS, MADISON COUNTY, ALABAMA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — This Hydraulic data was reviewed and approved by FEMA during the initial MT-2 processing. Recent developments in digital terrain and geospatial database management...

  2. HYDRAULICS, HAMPDEN COUNTY, MA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulic data in this submittal include spatial datasets and model outputs necessary for computation of the 1-percent flooding extent. The minimum requirement for...

  3. Hydraulic wind energy conversion system

    Energy Technology Data Exchange (ETDEWEB)

    1981-07-01

    The purpose of this research was to design, build and test a hydraulic wind energy system. This design used a three bladed turbine, which drove a hydraulic pump. The energy is transmitted from the pump through a long hose and into a hydraulic motor, where the energy is used. This wind system was built and tested during the winter of 1980-1981. The power train included a five meter, three bladed wind turbine, a 9.8:1 ratio gearbox, a 1.44 cubic inch displacement pump with a small supercharge gear pump attached. The hydraulic fluid was pumped through a 70', 3/4'' I-D-high pressure flexhose, then through a volume control valve and into a 1.44 cubic inch displacement motor. The fluid was returned through a 70', 1'' I-D-flexhose.

  4. PLANETARY SYSTEM FORMATION IN THE PROTOPLANETARY DISK AROUND HL TAURI

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, Eiji; Hasegawa, Yasuhiro; Hayashi, Masahiko; Iguchi, Satoru, E-mail: eiji.akiyama@nao.ac.jp, E-mail: yasuhiro.hasegawa@nao.ac.jp [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

    2016-02-20

    We reprocess the Atacama Large Millimeter/Submillimeter Array (ALMA) long-baseline science verification data taken toward HL Tauri. Assuming the observed gaps are opened up by currently forming, unseen bodies, we estimate the mass of such hypothetical bodies based on the following two approaches: the Hill radius analysis and a more elaborate approach developed from the angular momentum transfer analysis in gas disks. For the former, the measured gap widths are used for estimating the mass of the bodies, while for the latter, the measured gap depths are utilized. We show that their masses are comparable to or less than the mass of Jovian planets. By evaluating Toomre’s gravitational instability (GI) condition and cooling effect, we find that the GI might be a mechanism to form the bodies in the outer region of the disk. As the disk might be gravitationally unstable only in the outer region of the disk, inward planetary migration would be needed to construct the current architecture of the observed disk. We estimate the gap-opening mass and show that type II migration might be able to play such a role. Combining GIs with inward migration, we conjecture that all of the observed gaps may be a consequence of bodies that might have originally formed at the outer part of the disk, and have subsequently migrated to the current locations. While ALMA’s unprecedented high spatial resolution observations can revolutionize our picture of planet formation, more dedicated observational and theoretical studies are needed to fully understand the HL Tauri images.

  5. 14 CFR 29.1435 - Hydraulic systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hydraulic systems. 29.1435 Section 29.1435... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1435 Hydraulic systems. (a) Design. Each hydraulic system must be designed as follows: (1) Each element of the hydraulic system...

  6. 14 CFR 23.1435 - Hydraulic systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hydraulic systems. 23.1435 Section 23.1435... § 23.1435 Hydraulic systems. (a) Design. Each hydraulic system must be designed as follows: (1) Each hydraulic system and its elements must withstand, without yielding, the structural loads expected...

  7. 46 CFR 28.405 - Hydraulic equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic system... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped...

  8. [Effect of astragalus polysaccharide on sensitivity of leukemic cell line HL-60 to NK cell cytotoxicity and its mechanism].

    Science.gov (United States)

    Zeng, Peng-Yun; Deng, Li-Li; Yue, Ling-Ling; Zhang, Lian-Sheng

    2012-08-01

    The objective of this study was to explore the effect of astragalus polysaccharide (APS) on sensitivity of leukemic cell line HL-60 to NK cell cytotoxicity and its mechanism. The cytotoxicities of NK cells against HL-60 cells were analyzed by LDH releasing assay at different effect-to-target cell ratios (E:T) before and after treated with APS. The gene expression of MHC class I chain-related (MICA) in HL-60 cells before and after APS treatment was assayed with RT-PCR. Protein expression of MICA in HL-60 cells was assayed by flow cytometry before and after treated by APS. The results showed that after treated with APS 15 mg/ml for 48 h, the cytotoxicities of NK cells against HL-60 cells enhanced at different effect-to-target (P HL-60 cells were up-regulated (P HL-60 cells, thus enhance sensitivity of HL-60 cells to cytotoxicity of NK cells.

  9. Critical factors influencing hospitals' adoption of HL7 version 2 standards: an empirical investigation.

    Science.gov (United States)

    Lin, Chi-Hung; Lin, I-Chun; Roan, Jin-Sheng; Yeh, Jehn-Shan

    2012-06-01

    Industry predictions focus on future e-hospitals that will integrate all stakeholders into a seamless network, allowing data to be shared. The Health Level Seven (HL7) is a standard for the interchange of data within the healthcare industry. It simplifies communication interfaces and allows the interoperability among heterogeneous applications. Although the benefits of adopting HL7 are well known, only a few hospitals in Taiwan have actually adopted it. What are the reasons behind the hospitals' lack of intention to adopt HL7? Most prior studies on HL7 have focused on technical issues and general overlooked the managerial side. This has caused a lack of understanding of factors influencing hospitals' decision on HL7 adoption. In fact, main reasons behind a hospital's decision on whether to adopt an innovative technology are more often related to organizational than purely technical issues. Hence, we pay our attention to these organizational considerations over HL7 adoption. Based on the Innovation Diffusion Theory, we proposed a research model to explore the critical factors influencing Taiwan hospitals' adoption intention of HL7. 472 questionnaires were distributed to all accredited hospitals in Taiwan and 122 were returned. The valid response rate was 25.21% (119). Factor analysis, logistic regression and Pearson Chi-square test were conducted to verify the research model. The results showed that environmental pressure, top management attitude towards HL7, staff's technology capability, system integrity, and hospital's scale were critical factors influencing hospitals' intention on whether to adopt HL7. The research findings provided the government, the healthcare industry, the hospital administrators and the academia with practical and theoretical references. These factors should be considered in planning promotion plan to encourage hospital adoption of HL7. This study also opens up a new research direction as well as a new viewpoint, and consequentially

  10. Advanced Performance Hydraulic Wind Energy

    Science.gov (United States)

    Jones, Jack A.; Bruce, Allan; Lam, Adrienne S.

    2013-01-01

    The Jet Propulsion Laboratory, California Institute of Technology, has developed a novel advanced hydraulic wind energy design, which has up to 23% performance improvement over conventional wind turbine and conventional hydraulic wind energy systems with 5 m/sec winds. It also has significant cost advantages with levelized costs equal to coal (after carbon tax rebate). The design is equally applicable to tidal energy systems and has passed preliminary laboratory proof-of-performance tests, as funded by the Department of Energy.

  11. The Design of Wheelchair Lifting Mechanism and Control System

    Institute of Scientific and Technical Information of China (English)

    ZHAO Cong; WANG Zheng-xing; JIANG Shi-hong; ZHANG Li; LIU Zheng-yu

    2014-01-01

    In order to achieve a wheelchair lift function, this paper designs a tri-scissors mechanism. Through the so-called H-type transmission and L-type swing rod, the three scissors mechanisms lift in the same rate with only one liner motor while ensuring the stability of the lift. Finite element analysis in ANSYS is performed to verify the material strength. The control system with Sunplus SCM achieves the voice control of wheelchair walking and lifting.

  12. Clinical application of palatal lift appliance in velopharyngeal incompetence

    Directory of Open Access Journals (Sweden)

    S Premkumar

    2011-01-01

    Full Text Available The presence of nasal air leak in cleft palate patients with velopharyngeal incompetence leads to characteristic nasal snort. The efficacy of the palatal lift appliance in patients with adequate velopharyngeal tissue with incompetence was tested. Speech quality improved after the wearing of palatal lift appliance. Palatal lift appliances are simple and efficient in reducing the nasal air leak. Ongoing speech therapy is necessary and advised for patients receiving palatal lift.

  13. Effects of box size, frequency of lifting, and height of lift on maximum acceptable weight of lift and heart rate for male university students in Iran.

    Science.gov (United States)

    Abadi, Ali Salehi Sahl; Mazlomi, Adel; Saraji, Gebraeil Nasl; Zeraati, Hojjat; Hadian, Mohammad Reza; Jafari, Amir Homayoun

    2015-10-01

    In spite of the widespread use of automation in industry, manual material handling (MMH) is still performed in many occupational settings. The emphasis on ergonomics in MMH tasks is due to the potential risks of workplace accidents and injuries. This study aimed to assess the effect of box size, frequency of lift, and height of lift on maximum acceptable weight of lift (MAWL) on the heart rates of male university students in Iran. This experimental study was conducted in 2015 with 15 male students recruited from Tehran University of Medical Sciences. Each participant performed 18 different lifting tasks that involved three lifting frequencies (1lift/min, 4.3 lifts/min and 6.67 lifts/min), three lifting heights (floor to knuckle, knuckle to shoulder, and shoulder to arm reach), and two box sizes. Each set of experiments was conducted during the 20 min work period using the free-style lifting technique. The working heart rates (WHR) were recorded for the entire duration. In this study, we used SPSS version 18 software and descriptive statistical methods, analysis of variance (ANOVA), and the t-test for data analysis. The results of the ANOVA showed that there was a significant difference between the mean of MAWL in terms of frequencies of lifts (p = 0.02). Tukey's post hoc test indicated that there was a significant difference between the frequencies of 1 lift/minute and 6.67 lifts/minute (p = 0. 01). There was a significant difference between the mean heart rates in terms of frequencies of lifts (p = 0.006), and Tukey's post hoc test indicated a significant difference between the frequencies of 1 lift/minute and 6.67 lifts/minute (p = 0.004). But, there was no significant difference between the mean of MAWL and the mean heart rate in terms of lifting heights (p > 0.05). The results of the t-test showed that there was a significant difference between the mean of MAWL and the mean heart rate in terms of the sizes of the two boxes (p = 0.000). Based on the results of

  14. The personal lift-assist device and lifting technique: a principal component analysis.

    Science.gov (United States)

    Sadler, Erin M; Graham, Ryan B; Stevenson, Joan M

    2011-04-01

    The personal lift-assist device (PLAD) is a non-motorised, on-body device that acts as an external force generator using the concept of stored elastic energy. In this study, the effect of the PLAD on the lifting kinematics of male and female lifters was investigated using principal component analysis. Joint kinematic data of 15 males and 15 females were collected using an opto-electronic system during a freestyle, symmetrical-lifting protocol with and without wearing the PLAD. Of the 31 Principal Components (PCs) retained in the models, eight scores were significantly different between the PLAD and no-PLAD conditions. There were no main effects for gender and no significant interactions. Results indicated that the PLAD similarly affected the lifting kinematics of males and females; demonstrating significantly less lumbar and thoracic flexion and significantly greater hip and ankle flexion when wearing the PLAD. These findings add to the body of work that suggest the PLAD may be a safe and effective ergonomic aid. STATEMENT OF RELEVANCE: The PLAD is an ergonomic aid that has been shown to be effective at reducing low back demands during manual materials handling tasks. This body of work establishes that the PLAD encourages safe lifting practices without adversely affecting lifting technique.

  15. 49 CFR 178.975 - Top lift test.

    Science.gov (United States)

    2010-10-01

    ... opposite lifting devices, so that the hoisting forces are applied vertically for a period of five minutes; and (ii) Lifted by each pair of diagonally opposite lifting devices so that the hoisting forces are... which it is designed until clear of the floor and maintained in that position for a period of...

  16. On lifting line analysis of horizontal axis windturbines

    Science.gov (United States)

    Politis, G. K.; Loukakis, T. A.

    A convergent iteration scheme for lifting line performance analysis of horizontal axis windturbines is presented. Lifting line correction factors are introduced and compared with those of Prandtl and Goldstein. Lifting line and strip theory formulations are applied for the calculation of performance for two windturbines. Differences of engineering importance are shown to exist in the prediction of the Power coefficient.

  17. 14 CFR 23.345 - High lift devices.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false High lift devices. 23.345 Section 23.345 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... lift devices. (a) If flaps or similar high lift devices are to be used for takeoff, approach or landing...

  18. 49 CFR 37.165 - Lift and securement use.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Lift and securement use. 37.165 Section 37.165... DISABILITIES (ADA) Provision of Service § 37.165 Lift and securement use. (a) This section applies to public... with disabilities with the use of securement systems, ramps and lifts. If it is necessary for the...

  19. 14 CFR 25.699 - Lift and drag device indicator.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Lift and drag device indicator. 25.699....699 Lift and drag device indicator. (a) There must be means to indicate to the pilots the position of each lift or drag device having a separate control in the cockpit to adjust its position. In addition...

  20. 14 CFR 25.345 - High lift devices.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false High lift devices. 25.345 Section 25.345... STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Flight Maneuver and Gust Conditions § 25.345 High lift...) A head-on gust of 25 feet per second velocity (EAS). (c) If flaps or other high lift devices are to...

  1. 14 CFR 23.369 - Rear lift truss.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Rear lift truss. 23.369 Section 23.369 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... lift truss. (a) If a rear lift truss is used, it must be designed to withstand conditions of reversed...

  2. δ-Lifting and δ-Supplemented Modules

    Institute of Scientific and Technical Information of China (English)

    Muhammet Tamer Kosan

    2007-01-01

    In this paper, δ-lifting and δ-supplemented modules are defined as generalizations of lifting and supplemented modules. Several properties of these modules are proved.New characterizations of δ-semiperect and b-perfect rings studied in [9] are obtained using δ-lifting and δ-supplemented modules.

  3. Technologies and Innovations for Hydraulic Pumps

    OpenAIRE

    Ivantysynova, Monika

    2016-01-01

    Positive displacement machines working as hydraulic pumps or hydraulic motors have always been, are and will be an essential part of any hydraulic system. Current trends and future demands on energy efficient systems will not only drastically increase the number of positive displacement machines needed for modern efficient hydraulic circuits but will significantly change the performance requirements of pumps and motors. Throttleless system configurations will change the landscape of hydraulic...

  4. Lifting a familiar object: visual size analysis, not memory for object weight, scales lift force.

    Science.gov (United States)

    Cole, Kelly J

    2008-07-01

    The brain can accurately predict the forces needed to efficiently manipulate familiar objects in relation to mechanical properties such as weight. These predictions involve memory or some type of central representation, but visual analysis of size also yields accurate predictions of the needed fingertip forces. This raises the issue of which process (weight memory or visual size analysis) is used during everyday life when handling familiar objects. Our aim was to determine if subjects use a sensorimotor memory of weight, or a visual size analysis, to predictively set their vertical lift force when lifting a recently handled object. Two groups of subjects lifted an opaque brown bottle filled with water (470 g) during the first experimental session, and then rested for 15 min in a different room. Both groups were told that they would lift the same bottle in their next session. However, the experimental group returned to lift a slightly smaller bottle filled with water (360 g) that otherwise was identical in appearance to the first bottle. The control group returned to lift the same bottle from the first session, which was only partially filled with water so that it also weighed 360 g. At the end of the second session subjects were asked if they observed any changes between sessions, but no subject indicated awareness of a specific change. An acceleration ratio was computed by dividing the peak vertical acceleration during the first lift of the second session by the average peak acceleration of the last five lifts during the first session. This ratio was >1 for the control subjects 1.30 (SEM 0.08), indicating that they scaled their lift force for the first lift of the second session based on a memory of the (heavier) bottle from the first session. In contrast, the acceleration ratio was 0.94 (0.10) for the experimental group (P < 0.011). We conclude that the experimental group processed visual cues concerning the size of the bottle. These findings raise the

  5. 75 FR 33320 - Notice of Issuance of Final Determination Concerning a Lift Unit for an Overhead Patient Lift...

    Science.gov (United States)

    2010-06-11

    ... SECURITY U.S. Customs and Border Protection Notice of Issuance of Final Determination Concerning a Lift Unit for an Overhead Patient Lift System; Correction AGENCY: U.S. Customs and Border Protection... notice that it had issued a final determination concerning the country of origin of a lift unit for an...

  6. Regulation of Histone Acetylation and Apoptosis by Trichostatin in HL-60 Cells

    Institute of Scientific and Technical Information of China (English)

    李新刚; 陈维凯; 谷俊侠; 崔国惠; 陈燕

    2004-01-01

    In order to examine the strong anticancer action and low toxicity of Trichostatin A(TSA), the effect of TSA was examined on the growth inhibition, acetylation of histone H3 and apoptosis in HL-60 cells by employing MTT, immunocytochemical techniques, and Annexin-V-FITC/PI assay. Our results showed that TSA could inhibit proliferation of HL- 60 cells in a time- and dose-dependent manner, and the IC50 at the 36th h was 100 ng/ml. The apoptosis-inducing effect of TSA on HL-60 cells was also time- and dose-dependent. But it didn't demonstrate apparent apoptosis induction in NPBMNCs within specific dose and time range. Both of the acetylation of histone H3 in HL-60 cells and NPBMNCs increased significantly (P<0.05) after treated with 100 ng/ml TSA for 4 h. However, there was no significant differences between the two groups (P>0.05). It is concluded that TSA can inhibit growth and induce apoptosis of HL-60 cells in a time- and dosedependent manner, and is able to selectively induce apoptosis in HL-60 cells but does not respond in NPBMNCs under the same conditions. The difference of TSA between HL-60 cells and NPBMNCs can't be explained by the regulation of histone acetylation.

  7. Study on human promyelocytic leukemia HL-60 cells apoptosis induced by fucosterol.

    Science.gov (United States)

    Ji, Yu-Bin; Ji, Chen-Feng; Yue, Lei

    2014-01-01

    In this study, we investigated the effect of fucosterol on HL-60 and the molecular mechanism. HL-60 Cells were treated with fucosterol, and 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) method was used to study fucosterol anti-tumor activity. Morphology of HL-60 cells was observed. Flow cytometry (FCM) was employed to detect the cell cycle. Laser scanning confocal microscope (LSCM) was used to analyze mitochondrial membrane potential (MMP) and the expressions of Fas, FasL, Fadd and Caspase-8. Western blot was performed to analyze the expressions of Cyt-C, Pro-Caspase-9 and Pro-Caspase-3. Caspase activity kits were used to determine the activity of Caspase-9, Caspase-8 and Caspase-3. The results showed fucosterol could inhibit the growth of HL-60 cells, and the cell cycle was arrested at G2/M phase. HL-60 cells showed obvious apoptosis morphology. After being treated with fucosterol for 24 h, HL-60 cells decreased MMP, induced Cyt-C release and Caspase-9, Caspase-3 activation. Fucosterol also increased the protein expression of Fas, FasL, Fadd and Caspase-8. Moreover, the activity of Caspase-9, Caspase-8 and Caspase-3 was increased significantly. In conclusion, Fucosterol can induce HL-60 cells apoptosis, suggesting that it may be a potent agent for cancer prevention and treatment.

  8. DYNAMIC MODEL AND SIMULATION OF A NOVEL ELECTRO-HYDRAULIC FULLY VARIABLE VALVE SYSTEM FOR FOUR-STROKE AUTOMOTIVE ENGINES

    Institute of Scientific and Technical Information of China (English)

    WONG Pak-kin; TAM Lap-mou; LI Ke

    2007-01-01

    In modern four-stroke engine technology, variable valve timing and lift control offers potential benefits for making a high-performance engine. A novel electro-hydraulic fully variable valve train for four-stroke automotive engines is introduced. The construction of the nonlinear mathematic model of the valve train system and its dynamic analysis are also presented. Experimental and simulation results show that the novel electro-hydraulic valve train can achieve fully variable valve timing and lift control. Consequently the engine performance on different loads and speeds will be significantly increased. The technology also permits the elimination of the traditional throttle valve in the gasoline engines and increases engine design flexibility.

  9. Lift and Drag Measurements of Superhydrophobic Hydrofoils

    Science.gov (United States)

    Sur, Samrat; Kim, Jeong-Hyun; Rothstein, Jonathan

    2015-11-01

    For several years, superhydrophobic surfaces which are chemically hydrophobic with micron or nanometer scale surface features have been considered for their ability to reduce drag and produce slip in microfluidic devices. More recently it has been demonstrated that superhydrophobic surfaces reduce friction coefficient in turbulent flows as well. In this talk, we will consider that modifying a hydrofoil's surface to make it superhydrophobic has on the resulting lift and drag measurements over a wide range of angles of attack. Experiments are conducted over the range of Reynolds numbers between 10,000hydrofoil is made superhydrophobic. The hydrofoils are coated Teflon that has been hot embossed with a 325grit stainless steel woven mesh to produce a regular pattern of microposts. In addition to fully superhydrophobic hydrofoils, selectively coated symmetrical hydrofoils will also be examined to study the effect that asymmetries in the surface properties can have on lift and drag. Partially funded by NSF CBET-1334962.

  10. Lifting CERN entrepreneurs to new heights

    CERN Multimedia

    William Rode

    2014-01-01

    How can an international research institution help employees who wish to leave their comfort zone for the risky endeavour of starting a company? CERN encourages the creation of companies as a way of disseminating technology developed here. But what else can be done to foster these initiatives?   William Rode, a technical student in CERN’s Knowledge Transfer Group, studied spin-off creations in some leading research institutions as part of his Master's thesis in entrepreneurship at the Norwegian University of Science and Technology. William, who was offered a ticket to attend the Lift14 conference in Geneva, shares some insight into how we can support entrepreneurship at CERN: "A while ago I attended the Lift conference in Geneva. The conference explores the business and social implications of technology innovation through talks and workshops, as well as through art and discussion. Innovation is at the core of the conference and is reflected in the open-mindedness of th...

  11. Approximately isometric lifting in quasidiagonal extensions

    Institute of Scientific and Technical Information of China (English)

    FANG XiaoChun; ZHAO YiLe

    2009-01-01

    Let O→I→A→A/I→O be a short exact sequence of C*-algebras with A unital.Suppose that the extension O→I→A→A/I→O is quasidiagonal,then it is shown that any positive element (projection,partial isometry,unitary element,respectively) in A/I has a lifting with the same form which commutes with some quasicentral approximate unit of I consisting of projections.Furthermore,it is shown that for any given positive number e,two positive elements (projections,As an application,it is shown that for any positive numbers e and (u) in U(A/I)0,there exists u in U(A)0which is a lifting of (u) such that cel(u) < cel(u) +e.

  12. Lift and drag of cetacean flippers

    Science.gov (United States)

    Murray, Mark; Weber, Paul; Howle, Laurens; Fish, Frank

    2008-11-01

    Field observation and collection of biological samples has resulted in cetacean (whales, dolphins and porpoises) flipper geometry being known for most species. However, the hydrodynamic properties of cetacean flippers have not been rigorously tested and thus their performance characteristics are unknown. Here, conducting water tunnel testing using scale models of cetacean flippers derived via computed tomography (CT) scans, as well as computational fluid dynamic (CFD) simulations, we present a baseline work to determine the hydrodynamic characteristics of cetacean flippers. We found that flippers of similar planform shape had similar hydrodynamic performance characteristics. Furthermore, one group of flippers of planform shape similar to a modern swept wing was found to have lift coefficient versus angle of attack curves that were biphasic rather than linear in nature, which was caused by the onset of vortex-dominated lift. Drag coefficient versus angle of attack curves were found to be less dependant on planform shape.

  13. Particle Lifting Processes in Dust Devils

    Science.gov (United States)

    Neakrase, L. D. V.; Balme, M. R.; Esposito, F.; Kelling, T.; Klose, M.; Kok, J. F.; Marticorena, B.; Merrison, J.; Patel, M.; Wurm, G.

    2016-10-01

    Particle lifting in dust devils on both Earth and Mars has been studied from many different perspectives, including how dust devils could influence the dust cycles of both planets. Here we review our current understanding of particle entrainment by dust devils by examining results from field observations on Earth and Mars, laboratory experiments (at terrestrial ambient and Mars-analog conditions), and analytical modeling. By combining insights obtained from these three methodologies, we provide a detailed overview on interactions between particle lifting processes due to mechanical, thermal, electrodynamical and pressure effects, and how these processes apply to dust devils on Earth and Mars. Experiments and observations have shown dust devils to be effective lifters of dust given the proper conditions on Earth and Mars. However, dust devil studies have yet to determine the individual roles of each of the component processes acting at any given time in dust devils.

  14. Eisenhart lift for higher derivative systems

    Science.gov (United States)

    Galajinsky, Anton; Masterov, Ivan

    2017-02-01

    The Eisenhart lift provides an elegant geometric description of a dynamical system of second order in terms of null geodesics of the Brinkmann-type metric. In this work, we attempt to generalize the Eisenhart method so as to encompass higher derivative models. The analysis relies upon Ostrogradsky's Hamiltonian. A consistent geometric description seems feasible only for a particular class of potentials. The scheme is exemplified by the Pais-Uhlenbeck oscillator.

  15. Eisenhart lift for higher derivative systems

    Directory of Open Access Journals (Sweden)

    Anton Galajinsky

    2017-02-01

    Full Text Available The Eisenhart lift provides an elegant geometric description of a dynamical system of second order in terms of null geodesics of the Brinkmann-type metric. In this work, we attempt to generalize the Eisenhart method so as to encompass higher derivative models. The analysis relies upon Ostrogradsky's Hamiltonian. A consistent geometric description seems feasible only for a particular class of potentials. The scheme is exemplified by the Pais–Uhlenbeck oscillator.

  16. Eisenhart lift for higher derivative systems

    CERN Document Server

    Galajinsky, Anton

    2016-01-01

    The Eisenhart lift provides an elegant geometric description of a dynamical system of second order in terms of null geodesics of the Brinkmann-type metric. In this work, we attempt to generalize the Eisenhart method so as to encompass higher derivative models. The analysis relies upon Ostrogradsky's Hamiltonian. A consistent geometric description seems feasible only for a particular class of potentials. The scheme is exemplified by the Pais-Uhlenbeck oscillator.

  17. Efficacy of LIFT for recurrent anal fistula.

    Science.gov (United States)

    Lehmann, J-P; Graf, W

    2013-05-01

    Ligation of the intersphincteric fistula tract (LIFT) is a novel sphincter-preserving technique for anal fistula. This pilot study was designed to evaluate the results in patients with a recurrent fistula. Seventeen patients [nine men; median age 49 (range, 30-76) years] with a recurrent trans-sphincteric fistula were treated with a LIFT procedure between June 2008 and February 2011. All were followed prospectively for a median of 16 (range, 5-27) weeks with clinical examination. Fifteen followed for 13.5 (range, 8-26) months by clinical examination also had three-dimensional (3D) anal ultrasound. The duration of the procedure was 35 (range, 18-70) min. One patient developed a small local haematoma and one had a subcutaneous infection, but otherwise there was no morbidity. At follow up, 11 (65%) patients had a successful closure, two (12%) had a remaining sinus and four (23%) had a persistent fistula. The incidence of persistent or recurrent fistulae at 13.5 months was six (40%) of 15 patients. No de novo faecal incontinence was reported. LIFT is a safe procedure for patients with recurrent anal fistula, with healing at short-term and medium-term follow-up comparable with or superior to that of other sphincter-preserving techniques. Larger studies with a longer follow up are needed to define the ultimate role of LIFT in patients with recurrence. © 2013 The Authors. Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland.

  18. Unified treatment of lifting atmospheric entry

    Science.gov (United States)

    Nachtsheim, P. R.; Lehman, L. L.

    1980-01-01

    This paper presents a unified treatment of the effect of lift on peak acceleration during atmospheric entry. Earlier studies were restricted to different regimes because of approximations invoked to solve the same transcendental equation. This paper shows the connection between the earlier studies by employing a general expression for the peak acceleration and obtains solutions to the transcendental equation without invoking the earlier approximations. Results are presented and compared with earlier studies where appropriate.

  19. Dragonfly flight. III. Lift and power requirements.

    Science.gov (United States)

    Wakeling, JM; Ellington, CP

    1997-02-01

    A mean lift coefficient quasi-steady analysis has been applied to the free flight of the dragonfly Sympetrum sanguineum and the damselfly Calopteryx splendens. The analysis accommodated the yaw and accelerations involved in free flight. For any given velocity or resultant aerodynamic force (thrust), the damselfly mean lift coefficient was higher than that for the dragonfly because of its clap and fling. For both species, the maximum mean lift coefficient L was higher than the steady CL,max. Both species aligned their strokes planes to be nearly normal to the thrust, a strategy that reduces the L required for flight and which is different from the previously published hovering and slow dragonfly flights with stroke planes steeply inclined to the horizontal. Owing to the relatively low costs of accelerating the wing, the aerodynamic power required for flight represents the mechanical power output from the muscles. The maximum muscle mass-specific power was estimated at 156 and 166 W kg-1 for S. sanguineum and C. splendens, respectively. Measurements of heat production immediately after flight resulted in mechanical efficiency estimates of 13 % and 9 % for S. sanguineum and C. splendens muscles, respectively.

  20. Occupational lifting, fetal death and preterm birth

    DEFF Research Database (Denmark)

    Mocevic, Emina; Svendsen, Susanne Wulff; Jørgensen, Kristian Tore

    2014-01-01

    OBJECTIVE: We examined the association between occupational lifting during pregnancy and risk of fetal death and preterm birth using a job exposure matrix (JEM). METHODS: For 68,086 occupationally active women in the Danish National Birth Cohort, interview information on occupational lifting...... the JEM. We used Cox regression models with gestational age as underlying time variable and adjustment for covariates. RESULTS: We observed 2,717 fetal deaths and 3,128 preterm births within the study cohort. No exposure-response relation was observed for fetal death, but for women with a prior fetal...... death, we found a hazard ratio (HR) of 2.87 (95% CI 1.37, 6.01) for stillbirth (fetal death ≥22 completed gestational weeks) among those who lifted >200 kg/day. For preterm birth, we found an exposure-response relation for primigravid women, reaching a HR of 1.43 (95% CI 1.13, 1.80) for total loads >200...

  1. Dynamic response of Hovercraft lift fans

    Science.gov (United States)

    Moran, D. D.

    1981-08-01

    Hovercraft lift fans are subjected to varying back pressure due to wave action and craft motions when these vehicles are operating in a seaway. The oscillatory back pressure causes the fans to perform dynamically, exhibiting a hysteresis type of response and a corresponding degradation in mean performance. Since Hovercraft motions are influenced by variations in lift fan pressure and discharge, it is important to understand completely the nature of the dynamic performance of lift fans in order to completely solve the Hovercraft seakeeping problem. The present study was performed to determine and classify the instabilities encountered in a centrifugal fan operating against time-varying back pressure. A model-scale experiment was developed in which the fan discharge was directed into a flow-measuring device, terminating in a rotating valve which produced an oscillatory back pressure superimposed upon a mean aerodynamic resistance. Pressure and local velocity were measured as functions of time at several locations in the fan volute. The measurements permitted the identification of rotating (or propagating) stall in the impeller. One cell and two cell configurations were classified and the transient condition connecting these two configurations was observed. The mechanisms which lead to rotating stall in a centrifugal compressor are presented and discussed with specific reference to Hovercraft applications.

  2. Performance Improvements of the SPS Internal Beam Dump for the HL-LHC Beam

    CERN Document Server

    Velotti, F M; Bracco, C; Carlier, E; Chiggiato, P; Ferreira Somoza, J A; Goddard, B; Meddahi, M; Senaj, V; Uythoven, J

    2013-01-01

    The SPS internal beam dump has been designed for beam specifications well below the HL-LHC ones, and for modes of operation which may not be adequate for the HL-LHC era. The present system suffers from several limitations in the allowed intensity and energy range, and its vacuum performance affects nearby high-voltage kicker systems. In this report the limitations of the internal beam dump system are reviewed, and the possible improvements compared. Preliminary upgrade proposals are presented, taking into consideration the expected operational HL-LHC parameters.

  3. Isolation of furocoumarins from bergamot fruits as HL-60 differentiation-inducing compounds.

    Science.gov (United States)

    Kawaii, S; Tomono, Y; Katase, E; Ogawa, K; Yano, M

    1999-10-01

    The HL-60 differentiation-inducing compounds in bergamot fruits were isolated with column chromatography and identified as bergamottin, bergapten, and citropten by (1)H and (13)C NMR. Their HL-60 differentiation-inducing activity was measured by examining nitro blue tetrazolium (NBT) reducing, nonspecific acid esterase (NSE), specific esterase (SE), and phagocytic activities, and bergamottin showed the strongest activity among the coumarins isolated from bergamot fruits. The structure-activity relationship obtained from HL-60 differentiation assay suggests that hydrophobicity of furocoumarins is correlated with their activity.

  4. PML(NLS(-)) inhibits cell apoptosis and promotes proliferation in HL-60 cells.

    Science.gov (United States)

    Gao, Yuan-Mei; Zhong, Liang; Zhang, Xi; Hu, Xiu-Xiu; Liu, Bei-Zhong

    2013-01-01

    Promyelocytic leukemia (PML) is a cell-growth suppressor, and PML-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Studies have reported that neutrophil elastase(NE) cleaved bcr-1-derived PML-RARα in early myeloid cells leading to the removal of nuclear localization signal (NLS) from PML. The resultant PML without NLS named PML(NLS(-)). PML(NLS(-)) mainly locates and functions in the cytoplasm. PML(NLS(-)) may act in different ways from PML, but its biological characteristics have not been reported. In this study, the PML (NLS(-)) was silenced with shRNA [HL-60/pPML(NLS(-))-shRNA] and over-expressed by preparation of recombinant adenovirus [HL-60/pAd-PML(NLS(-))]. The mRNA and protein expression of PML(NLS(-)) were detected by RT-PCR and Western blot respectively. Cell proliferation in vitro was assessed by MTT assay. Flow cytometry (FCM) was used to detect apoptotic cells. The transcription of BCL-2, BAX and C-MYC was detected in HL-60/pAd-PML(NLS(-)) cells. Our results showed that compared to the control group, the expression of PML(NLS(-)) was significantly reduced in the HL-60/pPML(NLS(-))-shRNA cells, and increased significantly in the HL-60/pAd-PML(NLS(-)) cells. The proliferation was significantly inhibited in the HL-60/pPML(NLS(-))-shRNA cells in a time-dependent manner, but markedly promoted in the HL-60/pAd-PML(NLS(-)) cells treated with 60 μmol/L emodin. FCM revealed the apoptosis increased in HL-60/pPML(NLS(-))-shRNA cells, and decreased in the HL-60/pAd-PML(NLS(-)) cells. The expression of BAX decreased significantly, while that of BCL-2 and C-MYC increased significantly in HL-60/ pAd-PML(NLS(-)) cells. Down-regulation of PML(NLS(-)) expression inhibits the proliferation and induces the apoptosis of HL-60 cells. On the contrary, over-expression of PML(NLS(-)) promotes the proliferation and reduce the emodin-induced apoptosis of HL-60 cells.

  5. Superficial shoulder muscle co-activations during lifting tasks: Influence of lifting height, weight and phase.

    Science.gov (United States)

    Blache, Y; Dal Maso, F; Desmoulins, L; Plamondon, A; Begon, M

    2015-04-01

    This study aimed to assess the level of co-activation of the superficial shoulder muscles during lifting movement. Boxes containing three different loads (6, 12, and 18 kg) were lifted by fourteen subjects from the waist to shoulder or eye level. The 3D kinematics and electromyograms of the three deltoids, latissimus dorsi and pectoralis major were recorded. A musculoskeletal model was used to determine direction of the moment arm of these muscles. Finally an index of muscle co-activation named the muscle focus was used to evaluate the effects of lifting height, weight lifted and phase (pulling, lifting and dropping phases) on superficial shoulder muscle coactivation. The muscle focus was lower (more co-contraction) during the dropping phase compared to the two other phases (-13%, pmuscle activations and by a change in the direction of the muscle moment arm as a function of glenohumeral joint position. Consequently, the function of the shoulder superficial muscles varied with respect to the glenohumeral joint position. To increase the superficial muscle coactivation during the dropping phase may be a solution to increase glenohumeral joint stiffness. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Complex Fluids and Hydraulic Fracturing.

    Science.gov (United States)

    Barbati, Alexander C; Desroches, Jean; Robisson, Agathe; McKinley, Gareth H

    2016-06-07

    Nearly 70 years old, hydraulic fracturing is a core technique for stimulating hydrocarbon production in a majority of oil and gas reservoirs. Complex fluids are implemented in nearly every step of the fracturing process, most significantly to generate and sustain fractures and transport and distribute proppant particles during and following fluid injection. An extremely wide range of complex fluids are used: naturally occurring polysaccharide and synthetic polymer solutions, aqueous physical and chemical gels, organic gels, micellar surfactant solutions, emulsions, and foams. These fluids are loaded over a wide range of concentrations with particles of varying sizes and aspect ratios and are subjected to extreme mechanical and environmental conditions. We describe the settings of hydraulic fracturing (framed by geology), fracturing mechanics and physics, and the critical role that non-Newtonian fluid dynamics and complex fluids play in the hydraulic fracturing process.

  7. Hydraulic properties of ladle slags

    Directory of Open Access Journals (Sweden)

    J. Vlček

    2016-07-01

    Full Text Available The article presents results of examining of hydraulic properties of ladle slags formed during production of steel. The studied ladle slags were subjected to different cooling mode from the molten state. Based on the ability of the slag react with the water was assessed their hydraulic activity. The hydraulic properties are caused by the presence of minerals dicalcium silicate, tricalcium aluminate, mayenite, brownmillerite and dicalcium ferite. The emergence of required hydrating phases in the ladle slags is conditioned by a sufficient CaO content and their cooling rate. The contact the slag with water during processing and their ageing has a negative effect. The experiment has shown that the phase transformation of the mineral dicalcium silicate which occurs during cooling of the ladle slags cause their volume instability.

  8. HUNTING FOR PLANETS IN THE HL TAU DISK

    Energy Technology Data Exchange (ETDEWEB)

    Testi, L. [ESO, Karl Schwarzschild str. 2, D-85748 Garching bei Muenchen (Germany); Skemer, A.; Bailey, V.; Defrère, D.; Hinz, Ph.; Leisenring, J.; Vaz, A. [Steward Observatory, University of Arizona, 933 N. Cherry Ave., Tucson, AZ 85721 (United States); Henning, Th. [Max Planck Institute for Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Esposito, S. [INAF-Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5, I-50125 Firenze (Italy); Fontana, A. [INAF-Osservatorio Astronomico di Roma, Monte Porzio (Italy); Marconi, A. [Universitá degli Studi di Firenze, Dipartimento di Fisica e Astronomia, Firenze (Italy); Skrutskie, M. [University of Virginia, 530 McCormick Road, Charlottesville, VA 22904 (United States); Veillet, C., E-mail: ltesti@eso.org [LBT Observatory, University of Arizona, 933 N. Cherry Ave., Tucson, AZ 85721 (United States)

    2015-10-20

    Recent ALMA images of HL Tau show gaps in the dusty disk that may be caused by planetary bodies. Given the young age of this system, if confirmed, this finding would imply very short timescales for planet formation, probably in a gravitationally unstable disk. To test this scenario, we searched for young planets by means of direct imaging in the L′ band using the Large Binocular Telescope Interferometer mid-infrared camera. At the location of two prominent dips in the dust distribution at ∼70 AU (∼0.″5) from the central star, we reach a contrast level of ∼7.5 mag. We did not detect any point sources at the location of the rings. Using evolutionary models we derive upper limits of ∼10–15 M{sub Jup} at ≤0.5–1 Ma for the possible planets. With these sensitivity limits we should have been able to detect companions sufficiently massive to open full gaps in the disk. The structures detected at millimeter wavelengths could be gaps in the distributions of large grains on the disk midplane caused by planets not massive enough to fully open the gaps. Future ALMA observations of the molecular gas density profile and kinematics as well as higher contrast infrared observations may be able to provide a definitive answer.

  9. An ATLAS distributed computing architecture for HL-LHC

    CERN Document Server

    Campana, Simone; The ATLAS collaboration

    2017-01-01

    The ATLAS collaboration started a process to understand the computing needs for the High Luminosity LHC era. Based on our best understanding of the computing model input parameters for the HL-LHC data taking conditions, results indicate the need for a larger amount of computational and storage resources with respect of the projection of constant yearly budget for computing in 2026. Filling the gap between the projection and the needs will be one of the challenges in preparation for LHC Run-4. While the gains from improvements in offline software will play a crucial role in this process, a different model for data processing, management, access and bookkeeping should also be envisaged to optimise resource usage. In this contribution we will describe a straw man of this model, founded on basic principles such as single event level granularity for data processing and virtual data. We will explain how the current architecture will evolve adiabatically into the future distributed computing system, through the prot...

  10. Hunting for planets in the HL Tau disk

    CERN Document Server

    Testi, L; Henning, Th; Bailey, V; Defrere, D; Hinz, Ph; Leisenring, J; Vaz, A; Esposito, S; Fontana, A; Marconi, A; Skrutskie, M; Veillet, C

    2015-01-01

    Recent ALMA images of HL Tau show gaps in the dusty disk that may be caused by planetary bodies. Given the young age of this system, if confirmed, this finding would imply very short timescales for planet formation, probably in a gravitationally unstable disk. To test this scenario, we searched for young planets by means of direct imaging in the L'-band using the Large Binocular Telescope Interferometer mid-infrared camera. At the location of two prominent dips in the dust distribution at ~70AU (~0.5") from the central star we reach a contrast level of ~7.5mag. We did not detect any point source at the location of the rings. Using evolutionary models we derive upper limits of ~10-15MJup at <=0.5-1Ma for the possible planets. With these sensitivity limits we should have been able to detect companions sufficiently massive to open full gaps in the disk. The structures detected at mm-wavelengths could be gaps in the distributions of large grains on the disk midplane, caused by planets not massive enough to ful...

  11. Mechanisms of Extending Operation Regionin the HL-1M Tokamak

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Stable operating region in the HL-1M tokamak has been extended by means ofwall conditioning, core fuelling and current control techniques. The mechanisms of the extensionare analyzed in this paper. Lithiumization diminishes the impurities and hydrogen recycling tothe lowest level. After lithiumization a high density up to 7×1019 m-3 was obtained easily bystrong gas puffing with ordinary ohmic discharge alone. More attractively we found that metalLi-coating exhibited the effects of wall stabilization. The low qa limit with higher density wasextended by a factor of 1.5~2 in comparison with that for boronization, and 1.2 for siliconization.Siliconization not only extended stable operating region significantly by itself, but also provideda good target plasma for other experiments of raising density limit. Core fuelling schemes arefavourable especially for siliconized wall with a higher level of medium-Z impurity (Z=14).After siliconization the maximum density near to 1020 m-3 was achieved by a combination ofsupersonic molecule beam injection and multipellet injection. The new defined slope of Hugilllimit illustrating more clearly the situation under low qa and high ne discharges was created toindicate the new region extended by combining Ip ramp-up with core fuelling. The slope with alarge Murakami coefficient increased by a factor of 50~60 %.

  12. Nanostructured cavity devices for extracellular stimulation of HL-1 cells.

    Science.gov (United States)

    Czeschik, Anna; Rinklin, Philipp; Derra, Ulrike; Ullmann, Sabrina; Holik, Peter; Steltenkamp, Siegfried; Offenhäusser, Andreas; Wolfrum, Bernhard

    2015-01-01

    Microelectrode arrays (MEAs) are state-of-the-art devices for extracellular recording and stimulation on biological tissue. Furthermore, they are a relevant tool for the development of biomedical applications like retina, cochlear and motor prostheses, cardiac pacemakers and drug screening. Hence, research on functional cell-sensor interfaces, as well as the development of new surface structures and modifications for improved electrode characteristics, is a vivid and well established field. However, combining single-cell resolution with sufficient signal coupling remains challenging due to poor cell-electrode sealing. Furthermore, electrodes with diameters below 20 µm often suffer from a high electrical impedance affecting the noise during voltage recordings. In this study, we report on a nanocavity sensor array for voltage-controlled stimulation and extracellular action potential recordings on cellular networks. Nanocavity devices combine the advantages of low-impedance electrodes with small cell-chip interfaces, preserving a high spatial resolution for recording and stimulation. A reservoir between opening aperture and electrode is provided, allowing the cell to access the structure for a tight cell-sensor sealing. We present the well-controlled fabrication process and the effect of cavity formation and electrode patterning on the sensor's impedance. Further, we demonstrate reliable voltage-controlled stimulation using nanostructured cavity devices by capturing the pacemaker of an HL-1 cell network.

  13. A Micro Molecular Bipolar Outflow From HL Tau

    CERN Document Server

    Takami, Michihiro; Pyo, Tae-Soo; McGregor, Peter; Davis, Christopher

    2007-01-01

    We present detailed geometry and kinematics of the inner outflow toward HL Tau observed using Near Infrared Integral Field Spectograph (NIFS) at the Gemini-North 8-m Observatory. We analyzed H2 2.122 um emission and [Fe II] 1.644 um line emission as well as the adjacent continuum observed at a <0".2 resolution. The H2 emission shows (1) a bubble-like geometry to the northeast of the star, as briefly reported in the previous paper, and (2) faint emission in the southwest counterflow, which has been revealed through careful analysis. The emission on both sides of the star show an arc 1".0 away from the star, exhibiting a bipolar symmetry. Different brightness and morphologies in the northeast and southwest flows are attributed to absorption and obscuration of the latter by a flattened envelope and a circumstellar disk. The H2 emission shows a remarkably different morphology from the collimated jet seen in [Fe II] emission. The positions of some features coincide with scattering continuum, indicating that the...

  14. Planetary System Formation in Protoplanetary Disk around HL Tauri

    CERN Document Server

    Akiyama, Eiji; Hayashi, Masahiko; Iguchi, Satoru

    2015-01-01

    We re-process the Atacama Large Millimeter/Submillimeter Array (ALMA) long-baseline science verification data taken toward HL Tauri. As shown by the previous work, we confirm that the high spatial resolution (~ 0."019, corresponding to ~ 2.7 AU) dust continuum images at \\lambda = 0.87, 1.3, and 2.9 mm exhibit a multiple ring-like gap structure in the circumstellar disk. Assuming that the observed gaps are opened up by currently forming, unseen bodies, we estimate the mass of such hypothetical bodies based on following two approaches; the Hill radius analysis and a more elaborated approach developed from the angular momentum transfer analysis in gas disks. For the former, the measured gap widths are used for calibrating the mass of the bodies, while for the latter, the measured gap depths are utilized. We show that their masses are likely comparable to or less than the mass of Jovian planets, and then discuss an origin of the observed gap structure. By evaluating Toomre's gravitational instability (GI) conditi...

  15. Physics at HL-LHC with the upgraded ATLAS detector

    CERN Document Server

    Dell'Acqua, Andrea; The ATLAS collaboration

    2017-01-01

    The physics prospects at the luminosity upgrade of LHC, HL-LHC, with a data set equivalent to 3000 fb-1 simulated in the ATLAS detector, are presented and discussed. The ultimate precision attainable on measurements of 125 GeV Higgs boson couplings to elementary fermions and bosons is discussed, as well as the searches for partners associated with this new particle. The electroweak sector is further studied with the analysis of the vector boson scattering, testing the SM predictions at the LHC energy scale. Supersymmetry is still one of the best motivated extensions of the Standard Model. The current searches at the LHC have yielded sensitivity to TeV scale gluinos and 1st and 2nd generation squarks, as well as to 3rd generation squarks. The sensitivity to electro-weakinos has reached the hundreds of GeV mass range. Benchmark studies are presented to show how the sensitivity improves at the future high-luminosity LHC runs. Prospects for searches for new heavy bosons and dark matter candidates at 14 TeV pp col...

  16. The ATLAS computing challenge for HL-LHC

    CERN Document Server

    Campana, Simone; The ATLAS collaboration

    2016-01-01

    The ATLAS experiment successfully commissioned a software and computing infrastructure to support the physics program during LHC Run 2. The next phases of the accelerator upgrade will present new challenges in the offline area. In particular, at High Luminosity LHC (also known as Run 4) the data taking conditions will be very demanding in terms of computing resources: between 5 and 10 KHz of event rate from the HLT to be reconstructed (and possibly further reprocessed) with an average pile-up of up to 200 events per collision and an equivalent number of simulated samples to be produced. The same parameters for the current run are lower by up to an order of magnitude. While processing and storage resources would need to scale accordingly, the funding situation allows one at best to consider a flat budget over the next few years for offline computing needs. In this paper we present a study quantifying the challenge in terms of computing resources for HL-LHC and present ideas about the possible evolution of the ...

  17. ATLAS Pixel Detector Design For HL-LHC

    CERN Document Server

    Smart, Ben; The ATLAS collaboration

    2016-01-01

    The ATLAS Inner Detector will be replaced for the High-Luminosity LHC (HL-LHC) running in 2026. The new Inner Detector will be called the Inner Tracker (ITk). The ITk will cover an extended eta-range: at least to |eta|<3.2, and likely up to |eta|<4.0. The ITk will be an all-Silicon based detector, consisting of a Silicon strip detector outside of a radius of 362mm, and a Silicon pixel detector inside of this radius. Several novel designs are being considered for the ITk pixel detector, to cope with high-eta charged particle tracks. These designs are grouped into 'extended' and 'inclined' design-types. Extended designs have long pixel staves with sensors parallel to the beamline. High-eta particles will therefore hit these sensors at shallow angles, leaving elongated charge clusters. The length of such a charge cluster can be used to estimate the angle of the passing particle. This information can then be used in track reconstruction to improve tracking efficiency and reduce fake rates. Inclined designs ...

  18. ATLAS Pixel Detector Design For HL-LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00237541; The ATLAS collaboration

    2016-01-01

    The ATLAS Inner Detector will be replaced for the High-Luminosity LHC (HL-LHC) running in 2026. The new Inner Detector will be called the Inner Tracker (ITk). The ITk will cover an extended eta-range: at least to |eta|<3.2, and likely up to |eta|<4.0. The ITk will be an all-Silicon based detector, consisting of a Silicon strip detector outside of a radius of 362 mm, and a Silicon pixel detector inside of this radius. Several novel designs are being considered for the ITk pixel detector, to cope with high-eta charged particle tracks. These designs are grouped into 'extended' and 'inclined' design-types. Extended designs have long pixel staves with sensors parallel to the beamline, while inclined designs have sensors angled such that they point towards the interaction point. The relative advantages and challenges of these two classes of designs will be examined in this paper, along with the mechanical solutions being considered. Thermal management, radiation-length mapping, and electrical services will al...

  19. Particle confinement and density profile behaviour on HL-1M

    Institute of Scientific and Technical Information of China (English)

    Jiao Yi-Ming; Zhou Yan; Deng Zhong-Chao; Ding Xuan-Tong; Liu Yong; Wang En-Yao

    2005-01-01

    In this paper the density profile behaviour and the particle confinement operation regime on HL-1M have been studied under the pellet injection (PI), supersonic molecular beam injection (SMBI), gas puffing (GP) and lower hybrid current drive experimental situations. The relationships between density profile, particle confinement time and edge safe factor have been explored. The density profile, which is measured by six-channel far-infrared ray laser interferometer has been analysed by using the peaking coefficient calculation code. Changes of the outward and inward diffusion velocities before and after the peaking of the central density profile have been calculated using the global particle balance equations. The particle confinement operation regimes have been discussed. The peaking density profile can be easily obtained under the condition of efficient fuelling. In ohmic discharges, confinement time increases as the peaking density profile factor rises, and is saturated at a critical value related to the fuelling efficiency. The particle confinement time of SMBI lies between the values of GP and PI, and its value is about 3-5 times of the energy confinement time.

  20. ATLAS pixel detector design for the HL-LHC

    Science.gov (United States)

    Smart, B.

    2017-02-01

    The ATLAS Inner Detector will be replaced for the High-Luminosity LHC (HL-LHC) running in 2026. The new Inner Detector is called the Inner Tracker (ITk). The ITk will cover an extended η-range: at least to |η|<3.2, and likely up to 0|η|<4.. The ITk will be an all-Silicon based detector, consisting of a Silicon strip detector outside of a radius of 362 mm, and a Silicon pixel detector inside of this radius. Several novel designs are being considered for the ITk pixel detector, to cope with high-eta charged particle tracks. These designs are grouped into `extended' and `inclined' design-types. Extended designs have long pixel staves with sensors parallel to the beamline, while inclined designs have sensors angled such that they point towards the interaction point. The relative advantages and challenges of these two classes of designs will be examined in this paper, along with the mechanical solutions being considered. Thermal management, radiation-length mapping, and electrical services will also be discussed.

  1. The CMS Silicon Pixel detector for HL-LHC

    CERN Document Server

    Steinbrueck, Georg

    2016-01-01

    The LHC is planning an upgrade program which will bring the luminosity to about 5~$\\times10^{34}$~cm$^{-2}$s$^{-1}$ in 2026, with the goal of an integrated luminosity of 3000 fb$^{-1}$ by the end of 2037. This High Luminosity scenario, HL-LHC, will present new challenges of higher data rates and increased radiation. To maintain its physics potential in this harsh environment, the CMS detector will undergo a major upgrade program known as the Phase II upgrade. The new Phase II pixel detector will require a high bandwidth readout system and highly radiation tolerant sensors and on-detector ASICs. Several technologies for the sensors are being studied. Serial powering schemes are under consideration to accommodate significant constraints on the system. These prospective designs, as well as new layout geometries that include very forward pixel discs with acceptance extended from $\\vert\\eta\\vert<2.4$ to $\\vert\\eta\\vert<4$, are presented together with performance estimates.

  2. Stability and Ergonomic Design Features of Tractor Mounted Hydraulic Elevator for Coconut Harvesting

    Directory of Open Access Journals (Sweden)

    Kishor P. Kolhe

    2011-01-01

    Full Text Available Problem statement: The most important design criterion of mechanized device is safety; safety comprises both the safety of operator and safety of maintenance personnel. Failures and safety of harvesting platform of Tractor Mounted Hydraulic Elevator (TMHE powered by tractor PTO was tested by Finite Element Method for the mechanical harvesting of coconut orchards using digital Ergonomic hart rate meter. The objective of this study was to study the stability of the THME by finite element method, operational safety and power requirement for the use of this elevator for coconut harvesting. Also to provide sufficient adjustment and space to account for variation in body sizes, ensure controls are situated within suitable reach and are properly marked. Approach: The Modal analysis was carried out for the whole assembly of tractor mounted hydraulic elevator by using Ansis software. The digital polar hart rate meter RS400TM having infrared connectivity sensor is used for recording the hart rates. The research work was conducted at, Dr. Balasaheb Sawant Kokan Krishi Vidyapeeth Dapoli. The harvesting of coconuts was performed by manual climbing labor and by tractor mounted hydraulic elevator. The technical assessments included the use of biomechanical models, vibration testing equipment, ODR, BPDS. The ergonomical evaluation results of the above study are correlates to decide the feasibility, safety and efficiency of Tractor mounted hydraulic elevator for coconut harvesting. The PTO rpm influence for the lifting and lowering of the harvesting platform was studied experimentally by using digital tachometer. Results: The better stability results with the controlled vibrations and frequency of the lifting platform and welded joints were recorded by keeping constrained boundary conditions. Ergonomically operational safe and controlled heart rates are recorded. Hence the labors can continuously do the coconut harvesting work by using the tractor mounted

  3. Hydraulic resistance of biofilms

    KAUST Repository

    Dreszer, C.

    2013-02-01

    Biofilms may interfere with membrane performance in at least three ways: (i) increase of the transmembrane pressure drop, (ii) increase of feed channel (feed-concentrate) pressure drop, and (iii) increase of transmembrane passage. Given the relevance of biofouling, it is surprising how few data exist about the hydraulic resistance of biofilms that may affect the transmembrane pressure drop and membrane passage. In this study, biofilms were generated in a lab scale cross flow microfiltration system at two fluxes (20 and 100Lm-2h-1) and constant cross flow (0.1ms-1). As a nutrient source, acetate was added (1.0mgL-1 acetate C) besides a control without nutrient supply. A microfiltration (MF) membrane was chosen because the MF membrane resistance is very low compared to the expected biofilm resistance and, thus, biofilm resistance can be determined accurately. Transmembrane pressure drop was monitored. As biofilm parameters, thickness, total cell number, TOC, and extracellular polymeric substances (EPS) were determined, it was demonstrated that no internal membrane fouling occurred and that the fouling layer actually consisted of a grown biofilm and was not a filter cake of accumulated bacterial cells. At 20Lm-2h-1 flux with a nutrient dosage of 1mgL-1 acetate C, the resistance after 4 days reached a value of 6×1012m-1. At 100Lm-2h-1 flux under the same conditions, the resistance was 5×1013m-1. No correlation of biofilm resistance to biofilm thickness was found; Biofilms with similar thickness could have different resistance depending on the applied flux. The cell number in biofilms was between 4×107 and 5×108 cellscm-2. At this number, bacterial cells make up less than a half percent of the overall biofilm volume and therefore did not hamper the water flow through the biofilm significantly. A flux of 100Lm-2h-1 with nutrient supply caused higher cell numbers, more biomass, and higher biofilm resistance than a flux of 20Lm-2h-1. However, the biofilm thickness

  4. Group Lifting Structures For Multirate Filter Banks, I: Uniqueness Of Lifting Factorizations

    Energy Technology Data Exchange (ETDEWEB)

    Brislawn, Christopher M [Los Alamos National Laboratory

    2008-01-01

    This paper studies two-channel finite impulse response (FIR) perfect reconstruction filter banks. The connection between filter banks and wavelet transforms is well-known and will not be treated here. Figure 1 depicts the polyphase-with-advance representation of a filter bank [6]. A lifting factorization, is a factorization of polyphase matrices into upper and lower triangular lifting matrices. The existence of such decompositions via the Euclidean algorithm was shown for general FIR perfect reconstruction filter banks in [9] and was subsequently refined for linear phase filter banks in [10], [6]. These latter works were motivated by the ISO JPEG 2000 image coding standard [11], [12], [10], which specifies whole-sample symmetric (WS, or FIR type 1 linear phase) filter banks, as in Figure 2(a), in terms of half-sample symmetric (RS, or FIR type 2) lifting filters.

  5. Controls of Hydraulic Wind Turbine

    Directory of Open Access Journals (Sweden)

    Zhang Yin

    2016-01-01

    Full Text Available In this paper a hydraulic wind turbine generator system was proposed based on analysis the current wind turbines technologies. The construction and principles were introduced. The mathematical model was verified using MATLAB and AMsim. A displacement closed loop of swash plate of motor and a speed closed loop of generator were setup, a PID control is introduced to maintain a constant speed and fixed frequency at wind turbine generator. Simulation and experiment demonstrated that the system can connect grid to generate electric and enhance reliability. The control system demonstrates a high performance speed regulation and effectiveness. The results are great significant to design a new type hydraulic wind turbine system.

  6. Implementing an HL7 version 3 modeling tool from an Ecore model.

    Science.gov (United States)

    Bánfai, Balázs; Ulrich, Brandon; Török, Zsolt; Natarajan, Ravi; Ireland, Tim

    2009-01-01

    One of the main challenges of achieving interoperability using the HL7 V3 healthcare standard is the lack of clear definition and supporting tools for modeling, testing, and conformance checking. Currently, the knowledge defining the modeling is scattered around in MIF schemas, tools and specifications or simply with the domain experts. Modeling core HL7 concepts, constraints, and semantic relationships in Ecore/EMF encapsulates the domain-specific knowledge in a transparent way while unifying Java, XML, and UML in an abstract, high-level representation. Moreover, persisting and versioning the core HL7 concepts as a single Ecore context allows modelers and implementers to create, edit and validate message models against a single modeling context. The solution discussed in this paper is implemented in the new HL7 Static Model Designer as an extensible toolset integrated as a standalone Eclipse RCP application.

  7. Present Status and Future Development of HL-2A Data Acquisition System

    Institute of Scientific and Technical Information of China (English)

    CHENLiaoyuan; LUOCuiwen; PANLi; YANGYang; XUZhengyu; HANQian

    2002-01-01

    HL-2A data acquisition system (DAS) was developed and used in engineering tests last year. The main parts of the system include the experiment network, the data acquisition and processing mechanisms, and the graph and character display equipments.

  8. 14-3-3ξ对HL-60和HL-60/VCR细胞增殖的抑制作用%Inhibitory Effect of 14-3-3ξ on the Proliferation of HL-60 Cells and HL-60/VCR Cells

    Institute of Scientific and Technical Information of China (English)

    梁蓉; 陈协群; 王哲; 熊华; 白庆咸; 高广勋; 董宝侠; 朱华锋

    2013-01-01

    This study was aimed to investigate the expression and role of 14-3-3ξ in the AML cell lines:sensitive HL-60 and drug-resistant HL-60/VCR cells.Semi-quantitative RT-PCR and Western blot were respectively used to examine the expression of mdr1 mRNA and Pgp in AML cell lines to validate the results of microarray.Western blot was performed to investigate the expression of Pgp,14-3-3ξ,and anti-apoptosic protein BCL-2,MCL-1 proteins.Immunofluorescence assay was used to detect the subcellular location of 14-3-3ξ protein in HL-60 and HL-60/VCR cells by laser scanning confocal microscopy.Transduction with siRNA was used to silence 14-3-3ξ in AML cell lines.Cell count method and flow cytometry of cell cycle were used to analyze the changes of growth of AML cells.The results found that mdr1 mRNA and Pgp did not expressed in HL-60 cells,but significantly overexpressed in HL-60/VCR cells.Except 14-3-3(o),the expression of other subtypes of 14-3-3 was higher in HL-60/VCR cells than that in HL-60 cells,especially 14-3-3ξ.The higher expression of 14-3-3ξ,BCL-2,MCL-1 protein was observed in HL-60/VCR cells than that in HL-60 cells.These results were same results from gene chip.It was also noticed that 14-3-3ξ was located in the cytoplasma and nuclei of AML cell lines,especially over-expressed in HL-60/VCR cells.Furthermore,suppression of 14-3-3ξ by RNA interference resulted in inhibition of the proliferation of AML cells with decreased protein expression of BCL-2 and MCL-1,especially in HL-60/VCR cells.It is concluded that 14-3-3ξ plays an important role in proliferation of AML cells and associates with BCL-2 and MCL-1 expression.These results suggested that development of therapy targeting 14-3-3ξ may provide novel,effective strategies for refractory and relapsed AML.%本研究旨在进一步探讨14-3-3ξ在急性髓系白血病(acute myeloid leukemia,AML)敏感细胞HL-60和耐药细胞HL-60/VCR中的表达和作用.用半定量RT-PCR和Western blot分

  9. EFFECTS OF THE HYPERTHERMIA AND HARRINGTONINE ON TELOMERASE ACTIVITY OF HL-60 CELLS

    Institute of Scientific and Technical Information of China (English)

    王宝燕; 张海涛; 李静

    2002-01-01

    Objective To understand the mechanism of the hype rthermia and harringtonine in purging of leukemia cells In Vitro. telomerase activity of HL-60 cells treated by hyperthermia (42℃ for one hour) and di fferent concentrations of Harringtonine were investigated.Methods Using Telomeric Repeats Amplification Protocol (TRAP) a nd ELISA techniques to analyze the telomerase activity of HL-60 cells. Results Our results showed that harringtonine inhibited the tel omerase activity of HL-60 cells in a dosage related manner. Moreover, the telom erase activity of HL-60 cells was significantly decreased after the hyperthermi a treatment as compared with untreated cells.Conclusion The effect of the hyperthermia and Harringtonine on purging leukemia cells In Vitro may be mediated by down regulation of telome rase activity of tumor cells.

  10. SMA Submillimeter Observations of HL Tau: Revealing a compact molecular outflow

    CERN Document Server

    Lumbreras, Alba M

    2014-01-01

    We present archival high angular resolution ($\\sim$ 2$''$) $^{12}$CO(3-2) line and continuum submillimeter observations of the young stellar object HL Tau made with the Submillimeter Array (SMA). The $^{12}$CO(3-2) line observations reveal the presence of a compact and wide opening angle bipolar outflow with a northeast and southwest orientation (P.A. = 50$^\\circ$), and that is associated with the optical and infrared jet emanating from HL Tau with a similar orientation. On the other hand, the 850 $\\mu$m continuum emission observations exhibit a strong and compact source in the position of HL Tau that has a spatial size of $\\sim$ 200 $\\times$ 70 AU with a P.A. $=$ 145$^\\circ$, and a dust mass of around 0.1 M$_\\odot$. These physical parameters are in agreement with values obtained recently from millimeter observations. This submillimeter source is therefore related with the disk surrounding HL Tau.

  11. SMA submillimeter observations of HL Tau: revealing a compact molecular outflow

    Energy Technology Data Exchange (ETDEWEB)

    Lumbreras, Alba M.; Zapata, Luis A. [Centro de Radioastronomía y Astrofísica, UNAM, Morelia (Mexico)

    2014-04-01

    We present archival high angular resolution (∼2'') {sup 12}CO(3-2) line and continuum submillimeter observations of the young stellar object HL Tau made with the Submillimeter Array. The {sup 12}CO(3-2) line observations reveal the presence of a compact and wide opening angle bipolar outflow with a northeast to southwest orientation (P.A. = 50°) that is associated with the optical and infrared jet emanating from HL Tau with a similar orientation. On the other hand, the 850 μm continuum emission observations exhibit a strong and compact source in the position of HL Tau that has a spatial size of ∼200 × 70 AU with a P.A. = 145° and a dust mass of around 0.1 M {sub ☉}. These physical parameters are in agreement with values obtained recently from millimeter observations. This submillimeter source is therefore related to the disk surrounding HL Tau.

  12. E3 Success Story - Rising Above the Rest: H&L Advantage

    Science.gov (United States)

    Through the Green Suppliers Network review process, H&L Advantage worked on site with Michigan's Department of Environmental Quality (DEQ) and The Right Place, to identify over a dozen improvement opportunities in August 2004.

  13. Integrating hydraulic equivalent sections into a hydraulic geometry study

    Science.gov (United States)

    Jia, Yanhong; Yi, Yujun; Li, Zhiwei; Wang, Zhaoyin; Zheng, Xiangmin

    2017-09-01

    Hydraulic geometry (HG) is an important geomorphic concept that has played an indispensable role in hydrological analyses, physical studies of streams, ecosystem and aquatic habitat studies, and sedimentology research. More than 60 years after Leopold and Maddock (1953) first introduced the concept of HG, researchers have still not uncovered the physical principles underlying HG behavior. One impediment is the complexity of the natural river cross section. The current study presents a new way to simplify the cross section, namely, the hydraulic equivalent section, which is generalized from the cross section in the ;gradually varied flow of an alluvial river; (GVFAR) and features hydrodynamic properties and bed-building laws similar to those of the GVFAR. Energy balance was used to derive the stage Z-discharge Q relationship in the GVFAR. The GVFAR in the Songhua River and the Yangtze River were selected as examples. The data, including measured discharge, river width, water stage, water depth, wet area, and cross section, were collected from the hydrological yearbooks of typical hydrological stations on the Songhua River and the Yangtze River from 1955 to 1987. The relationships between stage Z-discharge Q and cross-sectional area A-stage Z at various stations were analyzed, and ;at-a-station hydraulic geometry; (AHG) relationships were obtained in power-law forms. Based on derived results and observational data analysis, the Z-Q and Z-A relationships of AHG were similar to rectangular weir flows, thus the cross section of the GVFAR was generalized as a compound rectangular, hydraulic equivalent cross section. As to bed-building characteristics, the bankfull discharge method and the stage-discharge-relation method were used to calculate the dominant variables of the alluvial river. This hydraulic equivalent section has the same Z-Q relation, Z-A relation, dominant discharge, dominant river width, and dominant water depth as the cross section in the GVFAR. With the

  14. Upgrades to the LHC Injection and Beam Dumping Systems for the HL-LHC Project

    CERN Document Server

    Uythoven, Jan; Goddard, Brennan; Hrivnak, Jan; Lechner, Anton; Maciariello, Fausto; Mereghetti, Alessio; Perillo Marcone, Antonio; Vittal Shetty, N; Shetty, Nikhil Vittal; Steele, Genevieve

    2014-01-01

    The HL-LHC project will push the performance of the LHC injection and beam dumping systems towards new limits. This paper describes the systems affected and presents the new beam parameters for these systems. It also describes the studies to be performed to determine which sub-components of these systems need to be upgraded to fulfil the new HL-LHC requirements. The results from the preliminary upgrade studies for the injection absorbers TDI are presented.

  15. Prospects On Standard Model And Higgs Physics At The HL-LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00221160; The ATLAS collaboration

    2016-01-01

    The luminosity upgrade of LHC, HL-LHC, will provide a large statistics data set that allows precision measurements of the 125 GeV Higgs boson properties. In particular, couplings to elementary fermions and bosons will be measured at the level of a few \\% accuracy. Searches for Higgs boson pair production and BSM effects in the vector boson scattering, of primary importance in the investigations of the electroweak symmetry breaking mechanism, also represent crucial point in the HL-LHC physics programme.

  16. HL-2A tokamak disruption forecasting based on an artificial neural network

    Institute of Scientific and Technical Information of China (English)

    Wang Hao; Wang Ai-Ke; Yang Qing-Wei; Ding Xuan-Tong; Dong Jia-Qi; Sanuki H; Itoh K

    2007-01-01

    Artificial neural networks are trained to forecast the plasma disruption in HL-2A tokamak. Optimized network architecture is obtained. Saliency analysis is made to assess the relative importance of different diagnostic signals as network input. The trained networks can successfully detect the disruptive pulses of HL-2A tokamak. The results obtained show the possibiliry of developing a neural network predictor that intervenes well in edvance for avoiding plasma disruption or mitigating its effects.

  17. Semantic validation of the use of SNOMED CT in HL7 clinical documents

    Directory of Open Access Journals (Sweden)

    Heymans Stijn

    2011-07-01

    Full Text Available Abstract Background The HL7 Clinical Document Architecture (CDA constrains the HL7 Reference Information model (RIM to specify the format of HL7-compliant clinical documents, dubbed CDA documents. The use of clinical terminologies such as SNOMED CT® further improves interoperability as they provide a shared understanding of concepts used in clinical documents. However, despite the use of the RIM and of shared terminologies such as SNOMED CT®, gaps remain as to how to use both the RIM and SNOMED CT® in HL7 clinical documents. The HL7 implementation guide on Using SNOMED CT in HL7 Version 3 is an effort to close this gap. It is, however, a human-readable document that is not suited for automatic processing. As such, health care professionals designing clinical documents need to ensure validity of documents manually. Results We represent the CDA using the Ontology Web Language OWL and further use the OWL version of SNOMED CT® to enable the translation of CDA documents to so-called OWL ontologies. We formalize a subset of the constraints in the implementation guide on Using SNOMED CT in HL7 Version 3 as OWL Integrity Constraints and show that we can automatically validate CDA documents using OWL reasoners such as Pellet. Finally, we evaluate our approach via a prototype implementation that plugs in the Open Health Workbench. Conclusions We present a methodology to automatically check the validity of CDA documents which make reference to SNOMED CT® terminology. The methodology relies on semantic technologies such as OWL. As such it removes the burden from IT health care professionals of having to manually implement such guidelines in systems that use HL7 Version 3 documents.

  18. Complete genome sequence of "Thioalkalivibrio sulfidophilus" HL-EbGr7.

    Science.gov (United States)

    Muyzer, Gerard; Sorokin, Dimitry Yu; Mavromatis, Konstantinos; Lapidus, Alla; Clum, Alicia; Ivanova, Natalia; Pati, Amrita; d'Haeseleer, Patrick; Woyke, Tanja; Kyrpides, Nikos C

    2011-02-14

    "Thioalkalivibrio sulfidophilus" HL-EbGr7 is an obligately chemolithoautotrophic, haloalkaliphilic sulfur-oxidizing bacterium (SOB) belonging to the Gammaproteobacteria. The strain was found to predominate a full-scale bioreactor, removing sulfide from biogas. Here we report the complete genome sequence of strain HL-EbGr7 and its annotation. The genome was sequenced within the Joint Genome Institute Community Sequencing Program, because of its relevance to the sustainable removal of sulfide from bio- and industrial waste gases.

  19. CRITICALITY CURVES FOR PLUTONIUM HYDRAULIC FLUID MIXTURES

    Energy Technology Data Exchange (ETDEWEB)

    WITTEKIND WD

    2007-10-03

    This Calculation Note performs and documents MCNP criticality calculations for plutonium (100% {sup 239}Pu) hydraulic fluid mixtures. Spherical geometry was used for these generalized criticality safety calculations and three geometries of neutron reflection are: {sm_bullet}bare, {sm_bullet}1 inch of hydraulic fluid, or {sm_bullet}12 inches of hydraulic fluid. This document shows the critical volume and critical mass for various concentrations of plutonium in hydraulic fluid. Between 1 and 2 gallons of hydraulic fluid were discovered in the bottom of HA-23S. This HA-23S hydraulic fluid was reported by engineering to be Fyrquel 220. The hydraulic fluid in GLovebox HA-23S is Fyrquel 220 which contains phosphorus. Critical spherical geometry in air is calculated with 0 in., 1 in., or 12 inches hydraulic fluid reflection.

  20. DCS Hydraulics Submittal, Butler County, Alabama, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulics data includes spatial datasets and data tables necessary for documenting the hydraulic procedures for computing flood elevations for a flood insurance...

  1. DCS Hydraulics Submittal, Bullock County, Alabama, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulics data includes spatial datasets and data tables necessary for documenting the hydraulic procedures for computing flood elevations for a flood insurance...

  2. DCS Hydraulics Submittal, Covington County, Alabama, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydraulics data includes spatial datasets and data tables necessary for documenting the hydraulic procedures for computing flood elevations for a flood insurance...

  3. Adding HL7 version 3 data types to PostgreSQL

    CERN Document Server

    Havinga, Yeb; de Keijzer, Ander

    2010-01-01

    The HL7 standard is widely used to exchange medical information electronically. As a part of the standard, HL7 defines scalar communication data types like physical quantity, point in time and concept descriptor but also complex types such as interval types, collection types and probabilistic types. Typical HL7 applications will store their communications in a database, resulting in a translation from HL7 concepts and types into database types. Since the data types were not designed to be implemented in a relational database server, this transition is cumbersome and fraught with programmer error. The purpose of this paper is two fold. First we analyze the HL7 version 3 data type definitions and define a number of conditions that must be met, for the data type to be suitable for implementation in a relational database. As a result of this analysis we describe a number of possible improvements in the HL7 specification. Second we describe an implementation in the PostgreSQL database server and show that the data...

  4. Phorbol ester-mediated desensitization of histamine Hl receptors on a cultured smooth muscle cell line

    Energy Technology Data Exchange (ETDEWEB)

    Mitsuhashi, M.; Payan, D.G.

    1988-01-01

    The present study was undertaken in order to examine the effect of protein kinase C (PKC) on histamine Hl receptors, (HlR) present on the smooth muscle cell line, DDT/sub 1/MF-2. (/sup 3/H)-pyrilamine binding revealed that specific (/sup 3/H)-pyrilamine binding sites were reduced be pretreatment with 12-O-tetra-decanoylphorbol-13-acetate (TPA), an activator of PKC, but not the Kd. The TPA analogue, 4..cap alpha.. phorbol 12,13-didecanoate, which does not activate PKC, failed to induce down-regulation of HlR. TPA-induced down regulation of HlR was inhibited by pretreatment with 1-(5-Isoquinilinesulfonyl)-2-methylpiperazine dihydrochloride (H-7), a PKC inhibitor, in a dose dependent manner. The H-7 analogue, H-8, which is a less potent inhibitor of PKC, but a potent inhibitor of cyclic nucleotide dependent protein kinase, had no effect on HlR. Moreover, treatment with TPA inhibited histamine-induced increases in (Ca/sup 2 +/)/sub i/ in cells loaded with the fluorescent indicator, indo-1. These data suggest that HlR in DDT/sub 1/MF-2 cells were functionally regulated by PKC.

  5. CLONING AND EXPRESSION OF A GENE MEDIATINGγ-RADIATION-INDUCED APOPTOSIS IN HL-60 CELLS

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective To identify the member of the caspase family proteases involved in γ-radiation-induced apoptosis in HL-60 cells and to study the expression of the caspase gene in normal, apoptotic cells and in immortal tu mor cells. Methods By using degenerate oligonucleotide primers encoding the highly conserved peptides that were pre sent in all known caspases, we performed RT-PCR on poly(A)RNA from γ-radiation-induced apoptotic HL-60 cells. Caspase-3 mRNA in apoptotic HL-60 cells and in human tumor cell lines was analyzed by Northern blot. Results The amplified DNA fragment was identified with caspase-3 cDNA by cloning and sequencing. The Northern blot analysis of caspase-3 mRNA of different human tumor cell lines showed that the caspase-3 gene transcript was more highly ex pressed in leukemia cell lines and the SH-SY5Y cell line than in HeLa and MCF-7 cells. It was more highly expressed in the radiation-induced apoptotic HL-60 cells than in control HL-60 cells. Conclusion These results indicated that caspase-3 was involved in γ-radiation-induced apoptosis in HL-60 cells. The high level of expression of caspase-3 may aid efforts to understand the insensitivity of some tumor cells to radiation, their inherent ability to survive, and apop tosis.

  6. Ethanolic extract of propolis induces apoptosis of HL-60 cells in vitro

    Institute of Scientific and Technical Information of China (English)

    Yan Shi; Yana Li; Co-first author Naie Li; Min Yu; Dong Wang; Lijun Kong

    2016-01-01

    Objective The aim of the study was to investigate whether ethanolic extract of propolis inhibits the growth and induces apoptosis of HL-60 cel s. Methods HL-60 cel s were treated for 24, 48, 72 h with various concentrations ethanolic extracts of prop-olis (0, 50, 100, and 200 μg/mL). The proliferation of HL-60 cels was determined using the 3-(4,5-dimeth-ylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Subsequently, Hochest 33258 staining and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) were used to test the apoptosis of HL-60 cel s. We observed the expression levels of Bax and Bcl-2 in HL-60 cel s by immunohistochemistry. Results MTT assay showed that various concentrations of ethanolic extract of propolis had significant inhibitory efect on HL-60 cel proliferation (P Conclusion Ethanolic extract of propolis inhibits leukemia cel proliferation and induces apoptosis in vitro. Its mechanism may be related to the regulation of Bax and Bcl-2 expression and up-regulation of Bcl-2/Bax ratio.

  7. Differential impact of bortezomib on HL-60 and K562 cells.

    Science.gov (United States)

    Kliková, Katarína; Štefaniková, Andrea; Pilchová, Ivana; Hatok, Jozef; Chudý, Peter; Chudej, Juraj; Dobrota, Dušan; Račay, Peter

    2015-01-01

    Bortezomib (PS-341, or Velcade), reversible inhibitor of 20S proteasome approved for the treatment of multiple myeloma and mantle cell lymphoma, exhibited a cytotoxic effect toward other malignancies including leukaemia. In this study, we have documented that incubation of both HL-60 and K562 leukaemia cells with nanomolar concentrations of bortezomib is associated with the death of HL-60 cells observed within 24 hours of incubation with bortezomib and the death of K562 cells that were observed after 72 hours of incubation with bortezomib. The relative resistance of K562 cells to bortezomib correlated well with significantly higher expression of HSP27, HSP70, HSP90α, HSP90β and GRP75 in these cells. Incubation of both HL-60 and K562 cells with bortezomib induced a cleavage of HSP90β as well as expression of HSP70 and HSP90β but bortezomib did not affect levels of HSP27, HSP90α, GRP75 and GRP78. The death of both types of cells was accompanied with proteolytic activation of caspase 3 that was observed in HL-60 cells and proteolytic degradation of procaspase 3 in K562 cells. Our study has also pointed to essential role of caspase 8 in bortezomib-induced cleavage of HSP90β in both HL-60 and K562 cells. Finally, we have shown that bortezomib induced activation of caspase 9/caspase 3 axis in HL-60 cells, while the mechanism of death of K562 cells remains unknown.

  8. [Effect of honokiol on proliferation and apoptosis in HL-60 cells and its potential mechanism].

    Science.gov (United States)

    Fan, Jia-Xin; Zeng, Ying-Jian; Weng, Guang-Yang; Wu, Jian-Wei; Li, Zhang-Qiu; Li, Yuan-Ming; Zheng, Rong; Guo, Kun-Yuan

    2014-12-01

    This study was aimed to investigate the effect of Honokiol (HNK) on proliferation and apoptosis of acute myeloid leukemia HL-60 cells and its potential mechanism. Inhibitory effect of HNK on the HL-60 cell proliferation was detected by MTT assay. Flow cytometry was used to detect the change of cell cycle and AnnexinV/PI staining was used to detect apoptosis. Western blot was applied to analyze the cell cycle protein (cyclins), cyclin-dependent kinase (CDK), P53, P21, P27, BCL-2, BCL-XL, Bax, caspase-3/9 and proteins for MAPK signal pathway. The results showed that HNK could inhibit the proliferation of HL-60 cells in time- and dose dependent ways. HNK arrested HL-60 cells in G0/G1 phase, and S phase cells decreased significantly (P HL-60 cell apoptosis increased significantly with the upregulation of activated caspase-3, -9, BAX expression and the downregulation of BCL-2, BCL-XL expression. The MAPK subfamily, P38 and JNK were not significantly changed, but the expression of MEK1/2-ERK1/2 was significantly downregulated (P HL-60 cell apoptosis through the intervention of MEK1/2-ERK1/2 signaling pathway.

  9. [Effect of COX-2 inhibitor celecoxib on proliferation, apoptosis of HL-60 cells and its mechanism].

    Science.gov (United States)

    Xie, Xia; Li, Jie; Wang, Rui-Cang; Geng, Rui-Li; Wang, Su-Yun; Wang, Chao; Zhao, Xiao-Yun; Hao, Hong-Ling

    2014-06-01

    This study was aimed to investigate the effect of COX-2 inhibitor celecoxib on proliferation, apoptosis of human acute myeloid leukemia cell line HL-60 and its mechanism. HL-60 cells were cultured with different concentrations of celecoxib for 24 h. Cell proliferation was analyzed by CCK-8 assay, cell apoptosis and cell cycle distribution were detected by flow cytometry. Cyclin D1, cyclin E1 and COX-2 mRNA expressions were determined by RT-PCR. The results showed that after the HL-60 cells were treated with different concentrations of celecoxib for 24 h, the cell growth was significantly inhibited in a dose-dependent manner(r = 0.955), IC50 was 63.037 µmol/L of celecoxib. Celecoxib could effectively induce apoptosis in HL-60 cells also in dose-dependent manner(r = 0.988), blocked the HL-60 cells in the G0/G1 phase. The expression of cyclin D1, cyclin E1 and COX-2 mRNA were downregulated. It is concluded that celecoxib can inhibit the proliferation of HL-60 cells in dose-dependent manner, celecoxib causes cell G0/G1 arrest and induces cell apoptosis possibly through down-regulation of the cyclin D1 and cyclin E1 expression, and down-regulation of COX-2 expression respectively.

  10. AN EFFECTIVE SCHEDULING SCHEME FOR LIFT CLUBS

    Directory of Open Access Journals (Sweden)

    W. Van Wijck

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This paper describes a formula for scheduling the day-to-day operation of a lift club. The formula is remarkably simple, and can easily be implemented on a spreadsheet. It is also extremely flexible and can cater for almost any peculiarity that may arise. Much like a business, the lift club is viewed as an entity in its own right, rather than as a collection of individuals. The scheme can be used to generate interesting statistics such as percentage utilization of each member, average percentage utilization of all members, effective size of the lift club, etc. In addition, a graph, depicting each member's liability towards the club against time, can be generated. Finally, every member can obtain a record of his/her trip data over any specific period, which may be handy for income tax purposes.

    AFRIKAANSE OPSOMMING: Hierdie artikel beskryf 'n fonnule vir die dag-tot-dag skedulering van 'n saamryklub. Die fonnule is merkwaardig eenvoudig en kan maklik op 'n sigblad geimplementeer word. Dit is ook besonder buigsaam deurdat dit vir bykans enige gebeurlikheid voorsienning maak. Die voorgestelde skeduleringsmetode beskou die saamryklub as 'n entiteit in eie reg, en skeduleing word vanuit die saamryklub se oogpunt gedoen. Die skema kan gebruik word om interesante statistieke soos byvoorbeeld die persentasie benutting deur enige lid, die gemiddelde persentasie benutting deur aIle lede, die effektiewe grootte van die klub, ens., te genereer. Voorts kan 'n grafiek gegenereer word wat elke lid se aanspreeklikheid teenoor die klub as 'n funksie van tyd grafies vertoon. Laastens kan enige lid op enige stadium 'n rekord trek van die aantal saamrygeleenthede wat hy oor 'n bepaalde periode voorsien en ontvang het. Dit mag handig wees vir belasting doeleindes.

  11. High Pressure Hydraulic Distribution System

    Science.gov (United States)

    1991-05-20

    to 500 0 F. 5 cycles. 5000 F room temperature to 50001F; 45 ______________ Icycles The tesis planned for the distribution system demonstrator were...American Society for Testing and Materials ASTM D412 - Tension Testing of Vulcanized Rubber ASTM D571 - Testing Automotive Hydraulic Brake Hose Society of

  12. Hydraulic fracturing system and method

    Energy Technology Data Exchange (ETDEWEB)

    Ciezobka, Jordan; Salehi, Iraj

    2017-02-28

    A hydraulic fracturing system and method for enhancing effective permeability of earth formations to increase hydrocarbon production, enhance operation efficiency by reducing fluid entry friction due to tortuosity and perforation, and to open perforations that are either unopened or not effective using traditional techniques, by varying a pump rate and/or a flow rate to a wellbore.

  13. Hydraulic jumps in a channel

    DEFF Research Database (Denmark)

    Bonn, D.; Andersen, Anders Peter; Bohr, Tomas

    2009-01-01

    We present a study of hydraulic jumps with flow predominantly in one direction, created either by confining the flow to a narrow channel with parallel walls or by providing an inflow in the form of a narrow sheet. In the channel flow, we find a linear height profile upstream of the jump as expected...

  14. Hydraulic Fracture Containment in Sand

    NARCIS (Netherlands)

    Dong, Y.

    2010-01-01

    The mechanism of hydraulic fracturing in soft, high permeability material is considered fundamentally different from that in hard, low permeability rock, where a tensile fracture is created and conventional linear elastic fracture mechanics (LEFM) applies. The fracturing and associated modeling work

  15. Design of hydraulic recuperation unit

    Directory of Open Access Journals (Sweden)

    Jandourek Pavel

    2016-01-01

    Full Text Available This article deals with design and measurement of hydraulic recuperation unit. Recuperation unit consist of radial turbine and axial pump, which are coupled on the same shaft. Speed of shaft with impellers are 6000 1/min. For economic reasons, is design of recuperation unit performed using commercially manufactured propellers.

  16. A new linear type hydraulic motor

    Science.gov (United States)

    Jiang, Dong; Zhang, Tong; Li, Wenhua; Chen, Xinyang

    2017-08-01

    This paper proposes the design of liner type hydraulic motor on the base of inner curved radial piston hydraulic motor. The hydraulic cylinders of the new type motor are in the straight line which will improve the utilization of the axial space and different out power can be supplied by changes the number of cylinders. In this paper, the structure and working principle of the liner type hydraulic motor is introduced.

  17. Pure spinor equations to lift gauged supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Rosa, Dario; Tomasiello, Alessandro [Dipartimento di Fisica, Università di Milano-Bicocca, and INFN, sezione di Milano-Bicocca,I-20126 Milano (Italy)

    2014-01-31

    We rewrite the equations for ten-dimensional supersymmetry in a way formally identical to a necessary and sufficient G-structure system in N=2 gauged supergravity, where all four-dimensional quantities are replaced by combinations of pure spinors and fluxes in the internal space. This provides a way to look for lifts of BPS solutions without having to reduce or even rewrite the ten-dimensional action. In particular this avoids the problem of consistent truncation, and the introduction of unphysical gravitino multiplets.

  18. Variable-Compliance Couplings For Heavy Lifting

    Science.gov (United States)

    Kerley, James; Eklund, Wayne; Burkhardt, Raymond; Richardson, George W.

    1992-01-01

    New coupling devices contain manual or electronically controlled, motorized drives that vary stiffnesses. Short, clamped lengths of cable provide compliance. Using threaded rods, cables stretched, relaxed, or folded to make coupling more or less stiff. In more-advanced device, brackets holding cables moved by stepping motor via gearbox and ball screw. Motor operates under computer control with position feedback. Control computer commands greater stiffness during operations requiring precise positioning, and greater compliance to accommodate manufacturing tolerances. Intended for use in wrist joints of robotic manipulators and other industrial equipment that must lift heavy objects.

  19. Lambda-Lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, Olivier; Schultz, Ulrik Pagh

    2004-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda...... on the simple observation that all functions in each component need the same extra parameters and thus a transitive closure is not needed. We therefore simplify the search for extra parameters by treating each strongly connected component instead of each function as a unit, thereby reducing the time complexity...

  20. Lambda-lifting in Quadratic Time

    DEFF Research Database (Denmark)

    Danvy, O.; Schultz, U.P.

    2004-01-01

    Lambda-lifting is a program transformation that is used in compilers, partial evaluators, and program transformers. In this article, we show how to reduce its complexity from cubic time to quadratic time, and we present a flow-sensitive lambda-lifter that also works in quadratic time. Lambda...... on the simple observation that all functions in each component need the same extra parameters and thus a transitive closure is not needed. We therefore simplify the search for extra parameters by treating each strongly connected component instead of each function as a unit, thereby reducing the time complexity...

  1. Bone suture and lateral sinus lift surgery

    Directory of Open Access Journals (Sweden)

    Amin Rahpeyma

    2015-01-01

    Full Text Available Bone suture in lateral sinus lift has four indications. Three of them depend on creating a hole in the lateral maxillary sinus wall above the antrostomy window for securing the elevated medial maxillary sinus membrane to manage perforated Schneiderian membrane. Covering the buccal antrostomy window with the buccal fat pad (BFP for better nourishment of the inserted graft and as an alternative for bone tags in fixation of collagen membrane has been reported previously. A new indication for firmly anchoring the BFP to the medial maxillary sinus wall as the last resort for the management of perforated Schneiderian membrane is explained in this article.

  2. Fixed Wordsize Implementation of Lifting Schemes

    Science.gov (United States)

    Karp, Tanja

    2006-12-01

    We present a reversible nonlinear discrete wavelet transform with predefined fixed wordsize based on lifting schemes. Restricting the dynamic range of the wavelet domain coefficients due to a fixed wordsize may result in overflow. We show how this overflow has to be handled in order to maintain reversibility of the transform. We also perform an analysis on how large a wordsize of the wavelet coefficients is needed to perform optimal lossless and lossy compressions of images. The scheme is advantageous to well-known integer-to-integer transforms since the wordsize of adders and multipliers can be predefined and does not increase steadily. This also results in significant gains in hardware implementations.

  3. APOLLO 14: Lift off from lunar surface

    Science.gov (United States)

    1974-01-01

    APOLLO 14: The lunar module 'Falcon' lifts off from the lunar surface From the film documentary 'APOLLO 14: 'Mission to Fra Mauro'', part of a documentary series on the APOLLO missions made in the early '70's and narrated by Burgess Meredith. APOLO 14: Third manned lunar landing with Alan B. Shepard, Jr.,Stuart A. Roosa, and Edgar D. Mitchell. Landed in the Fra Mauro area on Ferurary 5, 1971; performed EVA, deployed lunar experiments, returned lunar samples. Mission Duration 216 hrs 1 min 58 sec

  4. Nanostructured cavity devices for extracellular stimulation of HL-1 cells

    Science.gov (United States)

    Czeschik, Anna; Rinklin, Philipp; Derra, Ulrike; Ullmann, Sabrina; Holik, Peter; Steltenkamp, Siegfried; Offenhäusser, Andreas; Wolfrum, Bernhard

    2015-05-01

    Microelectrode arrays (MEAs) are state-of-the-art devices for extracellular recording and stimulation on biological tissue. Furthermore, they are a relevant tool for the development of biomedical applications like retina, cochlear and motor prostheses, cardiac pacemakers and drug screening. Hence, research on functional cell-sensor interfaces, as well as the development of new surface structures and modifications for improved electrode characteristics, is a vivid and well established field. However, combining single-cell resolution with sufficient signal coupling remains challenging due to poor cell-electrode sealing. Furthermore, electrodes with diameters below 20 µm often suffer from a high electrical impedance affecting the noise during voltage recordings. In this study, we report on a nanocavity sensor array for voltage-controlled stimulation and extracellular action potential recordings on cellular networks. Nanocavity devices combine the advantages of low-impedance electrodes with small cell-chip interfaces, preserving a high spatial resolution for recording and stimulation. A reservoir between opening aperture and electrode is provided, allowing the cell to access the structure for a tight cell-sensor sealing. We present the well-controlled fabrication process and the effect of cavity formation and electrode patterning on the sensor's impedance. Further, we demonstrate reliable voltage-controlled stimulation using nanostructured cavity devices by capturing the pacemaker of an HL-1 cell network.Microelectrode arrays (MEAs) are state-of-the-art devices for extracellular recording and stimulation on biological tissue. Furthermore, they are a relevant tool for the development of biomedical applications like retina, cochlear and motor prostheses, cardiac pacemakers and drug screening. Hence, research on functional cell-sensor interfaces, as well as the development of new surface structures and modifications for improved electrode characteristics, is a vivid and

  5. Hydraulic characterization of " Furcraea andina

    Science.gov (United States)

    Rivera-Velasquez, M. F.; Fallico, C.; Molinari, A.; Santillan, P.; Salazar, M.

    2012-04-01

    The present level of pollution, increasingly involving groundwaters, constitutes a serious risk for environment and human health. Therefore the remediation of saturated and unsaturated soils, removing pollutant materials through innovative and economic bio-remediation techniques is more frequently required. Recent studies on natural fiber development have shown the effectiveness of these fibers for removal of some heavy metals, due to the lignin content in the natural fibers which plays an important role in the adsorption of metal cations (Lee et al., 2004; Troisi et al., 2008; C. Fallico, 2010). In the context of remediation techniques for unsaturated and/or saturated zone, an experimental approach for the hydraulic characterization of the "Furcraea andina" (i.e., Cabuya Blanca) fiber was carried out. This fiber is native to Andean regions and grows easily in wild or cultivated form in the valleys and hillsides of Colombia, Ecuador, and Peru. Fibers of "Furcraea andina" were characterized by experimental tests to determine their hydraulic conductivity or permeability and porosity in order to use this medium for bioremediation of contaminated aquifer exploiting the physical, chemical and microbial capacity of natural fiber in heavy metal adsorption. To evaluate empirically the hydraulic conductivity, laboratory tests were carried out at constant head specifically on the fibers manually extracted. For these tests we used a flow cell (used as permeameter), containing the "Furcraea andina" fibers to be characterized, suitably connected by a tygon pipe to a Marriott's bottle, which had a plastic tube that allow the adjustment of the hydraulic head for different tests to a constant value. By this experiment it was also possible to identify relationships that enable the estimation of permeability as a function of density, i.e. of the compaction degree of the fibers. Our study was carried out for three values of hydraulic head (H), namely 10, 18, and 25 cm and for each

  6. Approach Considerations in Aircraft with High-Lift Propeller Systems

    Science.gov (United States)

    Patterson, Michael D.; Borer, Nicholas K.

    2017-01-01

    NASA's research into distributed electric propulsion (DEP) includes the design and development of the X-57 Maxwell aircraft. This aircraft has two distinct types of DEP: wingtip propellers and high-lift propellers. This paper focuses on the unique opportunities and challenges that the high-lift propellers--i.e., the small diameter propellers distributed upstream of the wing leading edge to augment lift at low speeds--bring to the aircraft performance in approach conditions. Recent changes to the regulations related to certifying small aircraft (14 CFR x23) and these new regulations' implications on the certification of aircraft with high-lift propellers are discussed. Recommendations about control systems for high-lift propeller systems are made, and performance estimates for the X-57 aircraft with high-lift propellers operating are presented.

  7. Interjoint coordination and the personal lift-assist device.

    Science.gov (United States)

    Graham, Ryan B; Smallman, Catherine L W; Sadler, Erin M; Stevenson, Joan M

    2013-04-01

    It has been suggested that interjoint coordination may serve to reduce joint stress and muscular demand and to maintain balance during dynamic lifting tasks, thus having implications for safe lifting practices. Before recommending the use of an on-body ergonomic aid, the Personal Lift-Assist Device (PLAD), it is important to determine any effects this device may have on interjoint coordination. Principal component analyses were applied to relative phase angle waveforms, defining the hip-knee and lumbar spine-hip coordination of 15 males and 15 females during a repetitive lifting task. When wearing the PLAD, users lifted with more synchronous hip-knee and lumbar spine-hip coordination patterns (P lift (P < .01) for all conditions. No significant main effects of sex or significant interactions were observed on any of the outcome variables.

  8. Back injury prevention: a lift team success story.

    Science.gov (United States)

    Hefti, Kelly S; Farnham, Richard J; Docken, Lisa; Bentaas, Ruth; Bossman, Sharon; Schaefer, Jill

    2003-06-01

    Work related back injuries among hospital personnel account for high volume, high cost workers' compensation claims. These injuries can be life altering experiences, affecting both the personal and professional lives of injured workers. Lifting must be viewed as a skill involving specialized training and mandated use of mechanical equipment, rather than as a random task performed by numerous health care providers. The use of a lift team specially trained in body mechanics, lifting techniques, and the use of mandated mechanical equipment can significantly affect injury data, financial outcomes, and employee satisfaction. The benefits of a lift team extend beyond the effect on injury and financial outcomes--they can be used for recruitment and retention strategies, and team members serve as mentors to others by demonstrating safe lifting techniques. Ultimately, a lift team helps protect a valuable resource--the health care worker.

  9. Lift enhancement by dynamically changing wingspan in forward flapping flight

    Science.gov (United States)

    Wang, Shizhao; Zhang, Xing; He, Guowei; Liu, Tianshu

    2014-06-01

    Dynamically stretching and retracting wingspan has been widely observed in the flight of birds and bats, and its effects on the aerodynamic performance particularly lift generation are intriguing. The rectangular flat-plate flapping wing with a sinusoidally stretching and retracting wingspan is proposed as a simple model for biologically inspired dynamic morphing wings. Numerical simulations of the low-Reynolds-number flows around the flapping morphing wing are conducted in a parametric space by using the immersed boundary method. It is found that the instantaneous and time-averaged lift coefficients of the wing can be significantly enhanced by dynamically changing wingspan in a flapping cycle. The lift enhancement is caused by both changing the lifting surface area and manipulating the flow structures responsible to the vortex lift generation. The physical mechanisms behind the lift enhancement are explored by examining the three-dimensional flow structures around the flapping wing.

  10. Lift Enhancement by Dynamically Changing Wingspan in Forward Flapping Flight

    CERN Document Server

    Wang, Shizhao; He, Guowei; Liu, Tianshu

    2013-01-01

    Stretching and retracting wingspan has been widely observed in the flight of birds and bats, and its effects on the aerodynamic performance particularly lift generation are intriguing. The rectangular flat-plate flapping wing with a sinusoidally stretching and retracting wingspan is proposed as a simple model of biologically-inspired dynamic morphing wings. Direct numerical simulations of the low-Reynolds-number flows around the flapping morphing wing in a parametric space are conducted by using immersed boundary method. It is found that the instantaneous and time-averaged lift coefficients of the wing can be significantly enhanced by dynamically changing wingspan in a flapping cycle. The lift enhancement is caused not only by changing the lifting surface area, but also manipulating the flow structures that are responsible to the generation of the vortex lift. The physical mechanisms behind the lift enhancement are explored by examining the three-dimensional flow structures around the flapping wing.

  11. 14 CFR 25.1435 - Hydraulic systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hydraulic systems. 25.1435 Section 25.1435... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1435 Hydraulic systems. (a) Element design. Each element of the hydraulic system must be designed to: (1) Withstand the proof...

  12. 14 CFR 27.1435 - Hydraulic systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Hydraulic systems. 27.1435 Section 27.1435... STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Safety Equipment § 27.1435 Hydraulic systems. (a) Design. Each hydraulic system and its elements must withstand, without yielding, any structural loads...

  13. Linnainstallatsioonide festival "Lift 11" = Urban installations festival Lift 11 / Margit Aule, Margit Argus ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Aule, Margit, 1981-

    2012-01-01

    Linnainstallatsioonide festivalist "Lift 11", installatsioonidest. Festivali kuraatorid Margit Argus ja Margit Aule ning kaaskuraatorid Maarin Ektermann ja Ingrid Ruudi pälvisid EK arhitektuuri sihtkapitali 2011. a. arhitektuurialase tegevuse preemia avaliku linnaruumi mitmekesisust märkama, kasutama ning mõtestama ärgitanud ürituse korraldamise eest

  14. Linnainstallatsioonide festival "Lift 11" = Urban installations festival Lift 11 / Margit Aule, Margit Argus ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Aule, Margit, 1981-

    2012-01-01

    Linnainstallatsioonide festivalist "Lift 11", installatsioonidest. Festivali kuraatorid Margit Argus ja Margit Aule ning kaaskuraatorid Maarin Ektermann ja Ingrid Ruudi pälvisid EK arhitektuuri sihtkapitali 2011. a. arhitektuurialase tegevuse preemia avaliku linnaruumi mitmekesisust märkama, kasutama ning mõtestama ärgitanud ürituse korraldamise eest

  15. HSR High Lift Program and PCD2 Update

    Science.gov (United States)

    Kemmerly, Guy T.; Coen, Peter; Meredith, Paul; Clark, Roger; Hahne, Dave; Smith, Brian

    1999-01-01

    The mission of High-Lift Technology is to develop technology allowing the design of practical high lift concepts for the High-Speed Civil Transport (HSCT) in order to: 1) operate safely and efficiently; and 2) reduce terminal control area and community noise. In fulfilling this mission, close and continuous coordination will be maintained with other High-Speed Research (HSR) technology elements in order to support optimization of the overall airplane (rather than just the high lift system).

  16. Raman spectrum reveals Mesenchymal stem cells inhibiting HL60 cells growth

    Science.gov (United States)

    Su, Xin; Fang, Shaoyin; Zhang, Daosen; Zhang, Qinnan; Lu, Xiaoxu; Tian, Jindong; Fan, Jinping; Zhong, Liyun

    2017-04-01

    Though some research results reveals that Mesenchymal stem cells (MSCs) have the ability of inhibiting tumor cells proliferation, it remains controversial about the precise interaction mechanism during MSCs and tumor cells co-culture. In this study, combing Raman spectroscopic data and principle component analysis (PCA), the biochemical changes of MSCs or Human promyelocytic leukemia (HL60) cells during their co-culture were presented. The obtained results showed that some main Raman peaks of HL60 assigned to nucleic acids or proteins were greatly higher in intensity in the late stage of co-culture than those in the early stage of co-culture while they were still lower relative to the control group, implicating that the effect of MSCs inhibiting HL60 proliferation appeared in the early stage but gradually lost the inhibiting ability in the late stage of co-culture. Moreover, some other peaks of HL60 assigned to proteins were decreased in intensity in the early stage of co-culture relative to the control group but rebounded to the level similar to the control group in the late stage, showing that the content and structure changes of these proteins might be generated in the early stage but returned to the original state in the late stage of co-culture. As a result, in the early stage of MSCs-HL60 co-culture, along with the level of Akt phosphorylation of HL60 was lowered relative to its control group, the proliferation rate of HL60 cells was decreased. And in the late stage of co-culture, along with the level of Akt phosphorylation was rebounded, the reverse transfer of Raman peaks within 875-880 cm- 1 appeared, thus MSCs lost the ability to inhibit HL60 growth and HL60 proliferation was increased. In addition, it was observed that the peak at 811 cm- 1, which is a marker of RNA, was higher in intensity in the late stage than that in the control group, indicating that MSCs might be differentiated into myofibroblast-like MSCs. In addition, PCA results also exhibited

  17. EXPERIMENTAL STUDY OF EFFECTS OF OPERATING CONDITIONS ON THE FLOW CHARACTERISTICS OF WATER HYDRAULIC THROTTLE

    Institute of Scientific and Technical Information of China (English)

    Liu Yinshui; Nie Songlin; Zhu Yuquan; He Xiaofeng; Li Zhuangyun

    2004-01-01

    Experimental investigations are made on the effects of operating conditions on the flow characteristics of throttle when tap water is used as the working media. The researched throttles include cone poppet valve, ball valve, disc valve and dumping orifice. Operating condition includes poppet lift, working media, back pressure, medium temperature, etc. Because the vapourous pressure of water is much higher than that of oil, cavitation is easier to occur in water hydraulic elements and systems, so the effects of operating conditions on the cavitation characteristics of throttle are also researched.

  18. Sikkerhedsbestemmelser for beskæringsarbejde fra lift

    DEFF Research Database (Denmark)

    Jakobsen, Ole Sejr; Theilby, Frans

    2010-01-01

    Brug af lift til beskæring og fældning af træer er blevet udbredt i den grønne sektor. Som bruger er det vigtigt at kende den lift, man har valgt, og at arbejdet med motorsav foregår efter Arbejdstilsynets regler og anbefalinger.......Brug af lift til beskæring og fældning af træer er blevet udbredt i den grønne sektor. Som bruger er det vigtigt at kende den lift, man har valgt, og at arbejdet med motorsav foregår efter Arbejdstilsynets regler og anbefalinger....

  19. Adaptation of lift forces in object manipulation through action observation.

    Science.gov (United States)

    Reichelt, Andreas F; Ash, Alyssa M; Baugh, Lee A; Johansson, Roland S; Flanagan, J Randall

    2013-07-01

    The ability to predict accurately the weights of objects is essential for skilled and dexterous manipulation. A potentially important source of information about object weight is through the observation of other people lifting objects. Here, we tested the hypothesis that when watching an actor lift an object, people naturally learn the object's weight and use this information to scale forces when they subsequently lift the object themselves. Participants repeatedly lifted an object in turn with an actor. Object weight unpredictably changed between 2 and 7 N every 5th to 9th of the actor's lifts, and the weight lifted by the participant always matched that previously lifted by the actor. Even though the participants were uninformed about the structure of the experiment, they appropriately adapted their lifting force in the first trial after a weight change. Thus, participants updated their internal representation about the object's weight, for use in action, when watching a single lift performed by the actor. This ability presumably involves the comparison of predicted and actual sensory information related to actor's actions, a comparison process that is also fundamental in action.

  20. Masculinity and Lifting Accidents among Danish Ambulance Personnel

    DEFF Research Database (Denmark)

    Hansen, Claus D.; Nielsen, Kent J

    Background Work injuries related to lifting are the most prevalent among ambulance personnel (AP) despite the introduction of ‘assistive technologies’ (AT) that help reduce situations of manual lifting. One third of the AP report using AT only ‘sometimes’ and 10% report having lifted a patient...... alone. For those 5% scoring lowest on MRNI the probability of reporting lifting alone was 6% while this figure was 17% for those scoring above the 95th percentile. Conclusion This study suggests that male ambulance workers performance of masculinity might pose a threat to their safety. AP...

  1. Lift augmentation for highly swept wing aircraft

    Science.gov (United States)

    Rao, Dhanvada M. (Inventor)

    1993-01-01

    A pair of spaced slots, disposed on each side of an aircraft centerline and spaced well inboard of the wing leading edges, are provided in the wing upper surfaces and directed tangentially spanwise toward thin sharp leading wing edges of a highly swept, delta wing aircraft. The slots are individually connected through separate plenum chambers to separate compressed air tanks and serve, collectively, as a system for providing aircraft lift augmentation. A compressed air supply is tapped from the aircraft turbojet power plant. Suitable valves, under the control of the aircraft pilot, serve to selective provide jet blowing from the individual slots to provide spanwise sheets of jet air closely adjacent to the upper surfaces and across the aircraft wing span to thereby create artificial vortices whose suction generate additional lift on the aircraft. When desired, or found necessary, unequal or one-side wing blowing is employed to generate rolling moments for augmented lateral control. Trailing flaps are provided that may be deflected differentially, individually, or in unison, as needed for assistance in take-off or landing of the aircraft.

  2. AMS gets lift on space shuttle Discovery

    CERN Multimedia

    2009-01-01

    AMS-02, the CERN-recognized experiment that will seek dark matter, missing matter and antimatter in Space aboard the International Space Station (ISS), has recently got the green light to be part of the STS-134 NASA mission in 2010. Installation of AMS detectors in the Prévessin experiment hall.In a recent press release, NASA announced that the last or last-but-one mission of the Space Shuttle programme would be the one that will deliver AMS, the Alpha Magnetic Spectrometer, to the International Space Station. The Space Shuttle Discovery is due to lift off in July 2010 from Kennedy Space Center and its mission will include the installation of AMS to the exterior of the space station, using both the shuttle and station arms. "It wasn’t easy to get a lift on the Space Shuttle from the Bush administration," says professor Samuel Ting, spokesperson of the experiment, "since during his administration all the funds for space research w...

  3. Does Malleolus non-Lifting Tympanoplasty have any Advantage Over Malleus Lifting Technique?

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Vahidi

    2016-01-01

    Full Text Available Introduction: In order to achieve a higher success rate for tympanoplasty, different techniques have been developed, and a wide variety of grafting materials have been developed. One of the techniques currently receiving considerable attention involves not lifting the remaining of eardrum from the malleus and embedding the graft underneath in order to repair the eardrum correctly in its original position, as well as minimizing graft lateralization leading to progression of hearing rehabilitation. We compared the effects of tympanoplasty with and without malleus lifting on hearing loss in patients with chronic otitis media.   Materials and Methods: In this study, 30 consecutive patients diagnosed as having chronic otitis media without cholesteatoma were randomly assigned to two tympanoplasty groups; with or without malleus lifting. Air and bone conduction thresholds were recorded before and 45 days after the intervention.   Results: In groups, except for 8000 Hz, the air conduction was significantly improved following surgery. According to air conduction there was no difference between the groups before surgery at different frequencies, although it was improved to a greater degree in the group without lifting at 250 Hz postoperatively. The average post-operative air-bone gap (ABG gain was significantly higher in all study frequencies in the target group. One of the effects of this technique is inner-ear protection from physical trauma to the ossicular chain, and prevention of damage to bone conduction.   Conclusion:  A higher hearing threshold and also higher ABG gain can be achieved by not lifting the remaining eardrum from the malleus and embedding the graft undereath it, especially at lower frequencies.

  4. Fatigue rupture study of HL-3 Buccal Multiloops for simulation of oral movements%HL-3型颊侧多曲簧模拟口腔开闭口运动的抗疲劳断裂实验

    Institute of Scientific and Technical Information of China (English)

    潘宇; 侯录; 徐实谦

    2013-01-01

    BACKGROUND:Concerning the problem of the ruptured phenomenon in clinic work of HL-1 and HL-2 Buccal Multiloops removable appliance, we invented HL-3 Buccal Multiloops. OBJECTIVE:Through the Buccal Multiloops Fatigue Testing Machine which can imitate oral movements, to compare the fatigue strength of the HL-2 and HL-3 Buccal Multiloops in the same condition. METHODS:A pair of the HL-2 or HL-3 Buccal Multiloops with the completely symmetrical size, symmetrical height and symmetrical direction was fixed on the Buccal Multiloops Fatigue Testing Machine which could simulate oral movements, then keep the Buccal Multiloops Fatigue Testing Machine working until any Buccal Multiloops broke. The cyclic loading times of this pair Buccal Multiloops was recorded. Scanning electron microscope was used to observe the appearance of broken end of the Buccal Multiloops. RESULTS AND CONCLUSION:The cyclic loading times of HL-3 Buccal Multiloops were more than HL-2 Buccal Multiloops (P   目的:通过颊侧多曲簧仿真模拟试验仪模拟口腔开闭口运动,比较在相同条件下HL-2及HL-3型颊侧多曲簧的抗疲劳断裂强度。  方法:将HL-2及HL-3型颊侧多曲簧固定在颊侧多曲簧仿真模拟试验仪上,位置模拟口腔内相应位置,两侧大小、高度、方向完全对称,开动仪器开始模拟口腔开闭口运动直至任意一侧颊侧多曲簧出现断裂并计录此时开闭口循环次数;通过扫描电镜观察断裂颊侧多曲簧的断口形貌特征。  结果与结论:HL-3型颊侧多曲簧的开闭口循环次数明显多于HL-2型颊侧多曲簧(P<0.01),说明HL-3型颊侧多曲簧与HL-2型颊侧多曲簧相比具有更强的抗疲劳断裂强度;扫描电镜观察结果示,HL-2型颊侧多曲簧和HL-3型颊侧多曲簧断口均有明显的疲劳断裂特征,证明HL-2型颊侧多曲簧与HL-3型颊侧多曲簧的断裂均属于疲劳断裂;但在HL-3型颊侧多曲簧

  5. Guidance and control analysis of the entry of a lifting body personnel launch vehicle

    Science.gov (United States)

    Powell, Richard W.; Cruz, Christopher I.

    1991-01-01

    NASA is currently involved in definition studies of a Personnel Launch System (PLS) that could be used to transport people to and from low-earth orbit. This vehicle would serve both to complement the Space Shuttle and to provide alternative access to space in the event the Space Shuttle fleet were unavailable for a prolonged period. The PLS would consist of a manned spacecraft launched by an expendable vehicle, e.g., Titan 4. One promising candidate for the manned component of the PLS is the NASA Langley Research Center HL-20 lifting body. Many studies are currently underway to assess this vehicle, and one of the main areas of study is the development of the capability to successfully enter, glide to the landing site, and land. To provide this capability, guidance and control algorithms have been developed, incorporated into a six-degree-of-freedom simulation, and evaluation in the presence of off-nominal atmospheric conditions, consisting of both density variations and steady-state winds. In addition, the impact of atmospheric turbulence was examined for the portion of flight from Mach 3.5 to touchdown. This analysis showed that the vehicle remained controllable and could successfully land even in the presence of off-nominal atmospheric conditions.

  6. Thermal Hydraulic Performance of Tight Lattice Bundle

    Science.gov (United States)

    Yamamoto, Yasushi; Akiba, Miyuki; Morooka, Shinichi; Shirakawa, Kenetsu; Abe, Nobuaki

    Recently, the reduced moderation spectrum BWR has been studied. The fast neutron spectrum is obtained through triangular tight lattice fuel. However, there are few thermal hydraulic test data and thermal hydraulic correlation applicable to critical power prediction in such a tight lattice bundle. This study aims to enhance the database of the thermal hydraulic performance of the tight lattice bundle whose rod gap is about 1mm. Therefore, thermal hydraulic performance measurement tests of tight lattice bundles for the critical power, the pressure drop and the counter current flow limiting were performed. Moreover, the correlations to evaluate the thermal-hydraulic performance of the tight lattice bundle were developed.

  7. Design of hydraulic output Stirling engine

    Science.gov (United States)

    Toscano, W. M.; Harvey, A. C.; Lee, K.

    1983-01-01

    A hydraulic output system for the RE-1000 free piston stirling engine (FPSE) was designed. The hydraulic output system can be readily integrated with the existing hot section of RE-1000 FPSE. The system has two simply supported diaphragms which separate the engine gas from the hydraulic fluid, a dynamic balance mechanism, and a novel, null center band hydraulic pump. The diaphragms are designed to endure more than 10 billion cycles, and to withstand the differential pressure load as high as 14 MPa. The projected thermodynamic performance of the hydraulic output version of RE-1000 FPSE is 1.87 kW at 29/7 percent brake efficiency.

  8. [Differentiation of human promyelocytic leukemia HL-60 cells induced by proanthocyanidin and its mechanism].

    Science.gov (United States)

    Xie, Zhao-Yang; Wu, Bin-Hua; Yang, Zhi-Gang; Chen, Xiao-Fang; Chen, Qiu-Shen

    2013-08-01

    This study was purposed to investigate the proliferation, differentiation and apoptosis of human promyelocytic leukemia HL-60 cells induced by proanthocyanidin (PAC). HL-60 cells were incubated with 20 mg/L PAC for 24 h, the cell growth was evaluated by CCK-8 assay. the effect of PAC on HL-60 cells was evaluated and the cells morphology was observed by optical microscopy. Expression of CD14 and CD11b, and cell cycle were analyzed by flow cytometry. The results showed that the growth of HL-60 cells was inhibited after treatment with PAC of different concentration in a dose-dependent manner (P HL-60 cells with inhibition ratio (72.3 ± 1.8)% for 24 h. Microscopy displayed that some cells differentiated to relative mature cells after treating for 48 h. Expression of CD14 increased and the expression of CD11b increased a little after treating with 20 mg/L PAC for 24 h, the ratio of cells in G0/G1 phase increased, but the ratio of cells in S phase decreased. The mRNA and protein expression of P21 gene increased, but the protein expression of CDK4 and Cyclin D1 decreased. It is concluded that PAC may inhibit the proliferation of HL-60 cells in vitro, induces the differentiation of HL-60 cells, and arrests the cells in G0/G1 phase. The possible mechanism may be related to up-regulation of P21 gene expression and down-regulation of the protein expression of CDK4 and Cyclin D1.

  9. Knockdown of nucleophosmin by RNA interference reverses multidrug resistance in resistant leukemic HL-60 cells.

    Science.gov (United States)

    Lin, Minhui; Hu, Jianda; Liu, Tingbo; Li, Jing; Chen, Buyuan; Chen, Xinji

    2013-09-01

    Nucleophosmin, a multifunctional nucleolar phosphoprotein, is involved in many cellular activities. However, the role of NPM in drug-resistance of leukemia has not yet been explored. We designed and selected one shRNA targeting on NPM gene transduction into HL-60 and HL-60/ADR cell lines (an adriamycin resistant cell line) by lentivirus. Cell proliferation, apoptosis and differentiation were assessed. The expressions of the related genes and proteins were detected by real-time quantitative RT-PCR and Western blotting. The results showed obvious down-regulation of NPM mRNA and protein levels after NPM RNAi. NPM-targeted RNAi also resulted in many cellular changes, such as, suppressing cell proliferation and inducing cell differentiation. Down-regulation of NPM gene could arrest the cell cycle progression, an increase in the proportion of G0/G1 phase in knockdown groups. NPM gene silencing could also induce pro-apoptotic genes and proteins expression, and inhibit anti-apoptotic genes/proteins expression. Furthermore, IC50 of two chemotherapeutic agents (adriamycin and ADR; daunorubicin and DNR) to HL-60 and HL-60/ADR cells decreased, especially more remarkable on HL-60/ADR cells. IC50 of ADR on HL-60/ADR cells was reduced from 12.544 ± 0.851 μmol/L (before NPM RNAi) to 6.331 ± 0.522 μmol/L (after NPM RNAi), IC50 of DNR was reduced from 2.152 ± 0.143 μmol/L (before NPM RNAi) to 1.116 ± 0.093 μmol/L (after NPM RNAi). The relative reversal rate of HL-60/ADR cells on ADR was 50.2%, and on DNR was 48.9%. In conclusion, our results demonstrated that shRNA expression vectors could effectively reduce NPM expression and restore the drug sensitivity of resistant leukemic cells to conventional chemotherapeutic agents.

  10. Experimental-based Modelling and Simulation of Water Hydraulic Mechatronics Test Facilities for Motion Control and Operation in Environmental Sensitive Applications` Areas

    DEFF Research Database (Denmark)

    Conrad, Finn; Pobedza, J.; Sobczyk, A.

    2003-01-01

    proportional valves and servo actuators for motion control and power transmission undertaken in co-operation by Technical University, DTU and Cracow University of Technology, CUT. The results of this research co-operation include engineering design and test of simulation models compared with two mechatronic......The paper presents experimental-based modelling, simulation, analysis and design of water hydraulic actuators for motion control of machines, lifts, cranes and robots. The contributions includes results from on-going research projects on fluid power and mechatronics based on tap water hydraulic...... test rig facilities powered by environmental friendly water hydraulic servo actuator system. Test rigs with measurement and data acquisition system were designed and build up with tap water hydraulic components of the Danfoss Nessie® product family. This paper presents selected experimental...

  11. Growth inhibition and differentiation of promyelocytic cells (HL-60) induced by BC-4, an active principle from Boswellia carterii Birdw.

    Science.gov (United States)

    Jing, Y; Xia, L; Han, R

    1992-03-01

    The induction of cell differentiation and growth inhibition of HL-60 cells by Bc-4, an active principle from Boswellia carterii, was studied in vitro and in vivo. The proliferation of HL-60 cells was found to be inhibited by Bc-4 at a concentration of 5-10 micrograms/ml. Under the action of Bc-4, the acid phosphatase and NBT reduction activities in HL-60 cells were increased, and phagocytosis of cells was also induced. All these activities were concentration dependent. The HL-60 cells were induced by Bc-4 to differentiate into more mature cells morphologically. The in vivo growth of HL-60 cells in mouse subrenal capsules (SRC) and in diffusion chambers inoculated into mice was inhibited by Bc-4 at a dose of 50 mg/kg. The morphology of HL-60 cells treated by Bc-4 in diffusion chambers exhibited characteristics of mature granulocytic cells.

  12. Sensorimotor memory biases weight perception during object lifting

    Directory of Open Access Journals (Sweden)

    Vonne evan Polanen

    2015-12-01

    Full Text Available When lifting an object, the brain uses visual cues and an internal object representation to predict its weight and scale fingertip forces accordingly. Once available, tactile information is rapidly integrated to update the weight prediction and refine the internal object representation. If visual cues cannot be used to predict weight, force planning relies on implicit knowledge acquired from recent lifting experience, termed sensorimotor memory. Here, we investigated whether perception of weight is similarly biased according to previous lifting experience and how this is related to force scaling. Participants grasped and lifted series of light or heavy objects in a semi-randomized order and estimated their weights. As expected, we found that forces were scaled based on previous lifts (sensorimotor memory and these effects increased depending on the length of recent lifting experience. Importantly, perceptual weight estimates were also influenced by the preceding lift, resulting in lower estimations after a heavy lift compared to a light one. In addition, the weight estimations were negatively correlated with the magnitude of planned force parameters. This perceptual bias was only found if the current lift was light, but not heavy since the magnitude of sensorimotor memory effects had, according to Weber’s law, relatively less impact on heavy compared to light objects. A control experiment tested the importance of active lifting in mediating these perceptual changes and showed that when weights are passively applied on the hand, no effect of previous sensory experience is found on perception. These results highlight how fast learning of novel object lifting dynamics can shape weight perception and demonstrate a tight link between action planning and perception control. If predictive force scaling and actual object weight do not match, the online motor corrections, rapidly implemented to downscale forces, will also downscale weight estimation in

  13. Levator plate upward lift and levator muscle strength

    Science.gov (United States)

    Rostaminia, Ghazaleh; Peck, Jennifer; Quiroz, Lieschen; Shobeiri, S. Abbas

    2016-01-01

    Objective The aim of study was to compare digital palpation with the levator plate lift measured by endovaginal and transperineal dynamic ultrasound. Methods Dynamic transperineal and endovaginal ultrasound were performed as part of multicompartmental pelvic floor functional assessment. Patients were instructed to perform Kegels while a probe captured the video clip of the levator plate movement at rest and during contraction in 2D mid-sagittal posterior view. We measured the distance between the levator plate and the probe on endovaginal ultrasound as well as the distance between the levator plate and the gothic arch of the pubis in transperineal ultrasound. The change in diameter (lift) and a levator plate lift ratio (lift / rest) x 100) were calculated. Pelvic floor muscle strength was assessed by digital palpation and divided into functional and non-functional groups using the Modified Oxford Scale (MOS). Mean differences in levator plate upward lifts were compared by MOS score using student t-tests and analysis of variance (ANOVA). Results 74 women were available for analysis. The mean age was 55 (SD±11.9). When measured by vaginal dynamic ultrasound, mean values of the lift and lift/rest ratio increased with increasing MOS score (ANOVA p=0.09 and p=0.04, respectively). When MOS scores were categorized to represent non-functional (MOS 0-1) and functional (MOS 2-5) muscle strength groups, the mean values of the lift (3.2 mm vs. 4.6 mm, p=0.03) and lift/rest ratio (13% vs 20%, p=0.01) were significantly higher in women with functional muscle strength. All patients with ≥ 30% lift detected by vaginal ultrasound had functional muscle strength. Conclusions Greater levator plate lift ratio detected by dynamic endovaginal ultrasound was associated with higher muscle strength as determined by MOS. This novel measurement can be incorporated into ultrasound evaluation of the levator ani function. PMID:26333568

  14. Hydraulic fracture during epithelial stretching

    Science.gov (United States)

    Casares, Laura; Vincent, Romaric; Zalvidea, Dobryna; Campillo, Noelia; Navajas, Daniel; Arroyo, Marino; Trepat, Xavier

    2015-03-01

    The origin of fracture in epithelial cell sheets subject to stretch is commonly attributed to excess tension in the cells’ cytoskeleton, in the plasma membrane, or in cell-cell contacts. Here, we demonstrate that for a variety of synthetic and physiological hydrogel substrates the formation of epithelial cracks is caused by tissue stretching independently of epithelial tension. We show that the origin of the cracks is hydraulic; they result from a transient pressure build-up in the substrate during stretch and compression manoeuvres. After pressure equilibration, cracks heal readily through actomyosin-dependent mechanisms. The observed phenomenology is captured by the theory of poroelasticity, which predicts the size and healing dynamics of epithelial cracks as a function of the stiffness, geometry and composition of the hydrogel substrate. Our findings demonstrate that epithelial integrity is determined in a tension-independent manner by the coupling between tissue stretching and matrix hydraulics.

  15. Bio-based Hydraulic Fluids

    Science.gov (United States)

    2008-04-17

    currently formulated with vegetable oils (i.e., rapeseed , sun flower, corn, soybean, canola, coconut, etc.) and synthetic ester, such as polyol ester...2008 Vegetable Oil • Excellent lubrication • Nontoxic • Biodegradable • Derived from renewable resources such as rapeseed , sunflower, corn...Mineral Oil 100 SAE 15W-40 G Rapeseed 32 Commercial HF H Polyol ester 22 MIL-PRF-32073 Grade 2 I Canola - Cooking Oil *Hydraulic fluid 3717 April

  16. Fire Resistant Aircraft Hydraulic System.

    Science.gov (United States)

    1982-07-01

    and compounds based on new experimental elastomers as well as most commercially available elastomers were screened in seeking seals that were both...for hydraulic component testing. All of the available E6.5 stock was purchased for the screening tests. However, DuPont stated that other homologs of...with the lubricity and anti-wear additive olyvan A (molybdenum oxysulphide dithiocarbamate ) added in the quantity of less than one percent by weight

  17. [Reversing effects of emodin on multidrug resistance in resistant HL-60/ADR cells].

    Science.gov (United States)

    Chen, Ying-Yu; Li, Jing; Hu, Jian-Da; Zheng, Jing; Zheng, Zhi-Hong; Zhu, Liang-Fang; Chen, Xin-Ji; Lin, Zhen-Xing

    2013-12-01

    This study was aimed to investigate the reversing effects of emodin on multidrug resistance (MDR) in resistant HL-60/ADR cells, and to explore the underlying mechanisms. The MTT assay was used to assess the chemoresistance of HL-60/ADR cells to emodin and 8 chemotherapeutic agents commonly used in clinic. The reversal effects of emodin on MDR of HL-60/ADR cells were also evaluated by MTT method. DNA ploidy analysis and DNA Ladder assay were used to detect apoptosis-induced effects on HL-60/ADR cells via the adriamycin (ADR) and emodin combination. The expression changes of the drug resistance-associated genes and proteins were detected by RT-PCR and Western Blot respectively. The intracellular accumulation and subcellular distribution of ADR and DNR were measured by flow cytometry and confocal laser scanning microscopy. The results showed that emodin inhibited HL-60/ADR cell proliferation with an average IC50 value of 24.09 ± 1.72 µmol/L, which was similar to that of the parental HL-60 cells (average IC50 = 23.18 ± 0.87 µmol/L). HL-60/ADR cells were resistant to a variety of chemotherapeutic agents, such as ADR, DNR, VP16, VCR,Ara-C, HHT, MTZ and THP. The reversal multiple were between 1.58 and 4.12 after the treatment with low concentration of emodin combined with the above mentioned different agents. The combination of ADR with emodin showed the best reversal effects, and the typical hypodiploid peak (apoptotic peak) and DNA ladder could be detected after the co-treatment.In addition, emodin down-regulated the mRNA and protein expression levels of MRP1, TOPOIIβ, GST π and BCL-2. Furthermore, the addition of emodin enhanced ADR and DNR intracellular accumulation and subcellular distribution in HL-60/ADR cells in dose-dependent manner. It is concluded that the emodin shows reversing effects on the multidrug resistant HL-60/ADR cells, possibly via decreasing the expression levels of drug resistance-associated genes, increasing the intracellular accumulation of

  18. H/L transition time estimation in JET using conformal predictors

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, S., E-mail: sergio.gonzalez@ciemat.es [Asociacion EURATOM/CIEMAT para Fusion, Madrid 28040 (Spain); Vega, J. [Asociacion EURATOM/CIEMAT para Fusion, Madrid 28040 (Spain); Murari, A. [Consorzio RFX, Associazione EURATOM/ENEA per la Fusione, Padova 4-25127 (Italy); Pereira, A. [Asociacion EURATOM/CIEMAT para Fusion, Madrid 28040 (Spain); Dormido-Canto, S.; Ramirez, J.M. [Departamento de Informatica y Automatica, UNED, Madrid 28040 (Spain)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer H/L transitions have been predicted using H/L and L/H models. Black-Right-Pointing-Pointer Models have been built using conformal predictors to hedge the prediction with confidence and credibility measures. Black-Right-Pointing-Pointer Models have been trained using linear and radial basis function kernels. Black-Right-Pointing-Pointer Conformal measures have proven their usefulness to validate data-driven models. - Abstract: Recent advances in data mining allow the automatic recognition of physical phenomena in the databases of fusion devices without human intervention. This is important to create large databases of physical events (thereby increasing the statistical relevance) in an unattended manner. Important examples are the L/H and H/L transitions. In this contribution, a novel technique is introduced to automatically locate H/L transitions in JET by using conformal predictors. The focus is on H/L transitions because typically there is not a clear signature in the time series of the most widely available signals to recognize the change of confinement. Conformal predictors hedge their prediction by means of two parameters: confidence and credibility. The technique has been based on binary supervised classifiers to separate the samples of the respective confinement modes. Results with several underlying classifiers are presented.

  19. The VLA view of the HL Tau Disk - Disk Mass, Grain Evolution, and Early Planet Formation

    CERN Document Server

    Carrasco-Gonzalez, Carlos; Chandler, Claire J; Linz, Hendrik; Perez, Laura; Rodriguez, Luis F; Galvan-Madrid, Roberto; Anglada, Guillem; Birnstiel, Til; van Boekel, Roy; Flock, Mario; Klahr, Hubert; Macias, Enrique; Menten, Karl; Osorio, Mayra; Testi, Leonardo; Torrelles, Jose M; Zhu, Zhaohuan

    2016-01-01

    The first long-baseline ALMA campaign resolved the disk around the young star HL Tau into a number of axisymmetric bright and dark rings. Despite the very young age of HL Tau these structures have been interpreted as signatures for the presence of (proto)planets. The ALMA images triggered numerous theoretical studies based on disk-planet interactions, magnetically driven disk structures, and grain evolution. Of special interest are the inner parts of disks, where terrestrial planets are expected to form. However, the emission from these regions in HL Tau turned out to be optically thick at all ALMA wavelengths, preventing the derivation of surface density profiles and grain size distributions. Here, we present the most sensitive images of HL Tau obtained to date with the Karl G. Jansky Very Large Array at 7.0 mm wavelength with a spatial resolution comparable to the ALMA images. At this long wavelength the dust emission from HL Tau is optically thin, allowing a comprehensive study of the inner disk. We obtain...

  20. TPEN prevents rapid pacing-induced calcium overload and nitration stress in HL-1 myocytes.

    Science.gov (United States)

    Yang, Shusen; Xu, Wenjing; Dong, Zengxiang; Zhou, Mo; Lin, Chaolan; Jin, Hongbo; Su, Yafen; Li, Qingyu; Wang, Xu; Chang, Huiying; Han, Wei

    2015-08-01

    Atrial fibrillation (AF) is the most common cardiac arrhythmia. However, the current drug interference of antiarrhythmia has limited efficacy and off-target effects. Accumulating evidence has implicated a potential role of nitration stress in the pathogenesis of AF. The aim of the study was to determine whether TPEN provided antinitration effects on atrial myocytes during AF, especially under circumstances of nitration stress. We utilized a rapid paced HL-1 cells model for AF. The changes of electrophysiological characteristics and structure of paced HL-1 cells were determined by a patch clamp and a TEM method. The effects of TPEN on pacing and ONOO(-) pretreated HL-1 cells were examined using MTT assay, TUNEL technique, confocal microscope experiment, and Western blot analysis. The results revealed that ONOO(-) reduced the viability of HL-1 cells in a dose-dependent manner, and 1 μmol/L TPEN significantly ameliorated the damage caused by 50 μmol/L ONOO(-) (P nitration caused by pacing or pacing plus ONOO(-) (P nitration stress in HL-1 atrial myocytes during rapid pacing and circumstances of nitration stress. © 2015 John Wiley & Sons Ltd.

  1. H/L ratio as a measurement of stress in laying hens - methodology and reliability.

    Science.gov (United States)

    Lentfer, T L; Pendl, H; Gebhardt-Henrich, S G; Fröhlich, E K F; Von Borell, E

    2015-04-01

    Measuring the ratio of heterophils and lymphocytes (H/L) in response to different stressors is a standard tool for assessing long-term stress in laying hens but detailed information on the reliability of measurements, measurement techniques and methods, and absolute cell counts is often lacking. Laying hens offered different sites of the nest boxes at different ages were compared in a two-treatment crossover experiment to provide detailed information on the procedure for measuring and the difficulties in the interpretation of H/L ratios in commercial conditions. H/L ratios were pen-specific and depended on the age and aviary system. There was no effect for the position of the nest. Heterophiles and lymphocytes were not correlated within individuals. Absolute cell counts differed in the number of heterophiles and lymphocytes and H/L ratios, whereas absolute leucocyte counts between individuals were similar. The reliability of the method using relative cell counts was good, yielding a correlation coefficient between double counts of r > 0.9. It was concluded that population-based reference values may not be sensitive enough to detect individual stress reactions and that the H/L ratio as an indicator of stress under commercial conditions may not be useful because of confounding factors and that other, non-invasive, measurements should be adopted.

  2. ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM

    Institute of Scientific and Technical Information of China (English)

    Jia-jun Liu; Xin-yao Wu; Hui-ling Lu; Xiang-lin Pan; Jun Peng; Ren-wei Huang

    2004-01-01

    Objective To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism.Methods HL-60 cells in vitro in culture medium were given different concentrations oforidonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM),morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred.Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly.The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin.Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.

  3. Separation of blood cells using hydrodynamic lift

    Science.gov (United States)

    Geislinger, T. M.; Eggart, B.; Braunmüller, S.; Schmid, L.; Franke, T.

    2012-04-01

    Using size and deformability as intrinsic biomarkers, we separate red blood cells (RBCs) from other blood components based on a repulsive hydrodynamic cell-wall-interaction. We exploit this purely viscous lift effect at low Reynolds numbers to induce a lateral migration of soft objects perpendicular to the streamlines of the fluid, which closely follows theoretical prediction by Olla [J. Phys. II 7, 1533, (1997)]. We study the effects of flow rate and fluid viscosity on the separation efficiency and demonstrate the separation of RBCs, blood platelets, and solid microspheres from each other. The method can be used for continuous and label-free cell classification and sorting in on-chip blood analysis.

  4. Fixed Wordsize Implementation of Lifting Schemes

    Directory of Open Access Journals (Sweden)

    Tanja Karp

    2007-01-01

    Full Text Available We present a reversible nonlinear discrete wavelet transform with predefined fixed wordsize based on lifting schemes. Restricting the dynamic range of the wavelet domain coefficients due to a fixed wordsize may result in overflow. We show how this overflow has to be handled in order to maintain reversibility of the transform. We also perform an analysis on how large a wordsize of the wavelet coefficients is needed to perform optimal lossless and lossy compressions of images. The scheme is advantageous to well-known integer-to-integer transforms since the wordsize of adders and multipliers can be predefined and does not increase steadily. This also results in significant gains in hardware implementations.

  5. Fitness Tracker for Weight Lifting Style Workouts

    Energy Technology Data Exchange (ETDEWEB)

    Wihl, B. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-02-01

    This document proposes an early, high level design for a fitness tracking system which can automatically log weight lifting style workouts. The system will provide an easy to use interface both physically through the use of several wireless wristband style motion trackers worn on the limbs, and graphically through a smartphone application. Exercise classification will be accomplished by calibration of the user’s specific motions. The system will accurately track a user’s workout, miscounting no more than one repetition in every 20, have sufficient battery life to last several hours, work with existing smartphones and have a cost similar to those of current fitness tracking devices. This document presents the mission background, current state-of-theart, stakeholders and their expectations, the proposed system’s context and concepts, implementation concepts, system requirements, first sublevel function decomposition, possible risks for the system, and a reflection on the design process.

  6. Insulation Test Cryostat with Lift Mechanism

    Science.gov (United States)

    Fesmire, James E. (Inventor); Dokos, Adam G. (Inventor)

    2016-01-01

    A multi-purpose, cylindrical thermal insulation test apparatus is used for testing insulation materials and systems of materials using a liquid boil-off calorimeter system for absolute measurement of the effective thermal conductivity (k-value) and heat flux of a specimen material at a fixed environmental condition (cold-side temperature, warm-side temperature, vacuum pressure level, and residual gas composition). An inner vessel receives liquid with a normal boiling point below ambient temperature, such as liquid nitrogen, enclosed within a vacuum chamber. A cold mass assembly, including upper and lower guard chambers and middle test vessel, is suspended from a lid of the vacuum canister. Each of the three chambers is filled and vented through a single feedthrough. All fluid and instrumentation feedthroughs are mounted and suspended from a top domed lid allowing easy removal of the cold mass. A lift mechanism allows manipulation of the cold mass assembly and insulation test article.

  7. Vector lifting schemes for stereo image coding.

    Science.gov (United States)

    Kaaniche, Mounir; Benazza-Benyahia, Amel; Pesquet-Popescu, Béatrice; Pesquet, Jean-Christophe

    2009-11-01

    Many research efforts have been devoted to the improvement of stereo image coding techniques for storage or transmission. In this paper, we are mainly interested in lossy-to-lossless coding schemes for stereo images allowing progressive reconstruction. The most commonly used approaches for stereo compression are based on disparity compensation techniques. The basic principle involved in this technique first consists of estimating the disparity map. Then, one image is considered as a reference and the other is predicted in order to generate a residual image. In this paper, we propose a novel approach, based on vector lifting schemes (VLS), which offers the advantage of generating two compact multiresolution representations of the left and the right views. We present two versions of this new scheme. A theoretical analysis of the performance of the considered VLS is also conducted. Experimental results indicate a significant improvement using the proposed structures compared with conventional methods.

  8. WECS incompressible Lifting Surface Aerodynamics (WILSA)

    Energy Technology Data Exchange (ETDEWEB)

    Suciu, E.; Morino, L.

    1976-05-01

    A method is described for computing the distribution for a zero-thickness horizontal axis windmill, as well as for obtaining the power coefficient. The problem is formulated in terms of velocity potential, and the study deals with a nonlinear finite-element lifting-surface analysis of horizontal-axis windmills in a steady incompressible, inviscid, irrotational flow, with a prescribed helicoidal wake. A zero-order-finite-element analysis is used with a straight-vortex line wake. The correct wake geometry is obtained and the pressure coefficient calculated using both linearized and nonlinear forms of the Bernoulli Theorem. The numerical results compare well with those obtained with Windmill Incompressible Complex Configuration Aerodynamics (WICCA), a computer program for solving the same problem which uses a completely different integral equation. A number of suggestions are offered to improve the model presented.

  9. Development of a Marine Propeller With Nonplanar Lifting Surfaces

    DEFF Research Database (Denmark)

    Andersen, Poul; Friesch, Jürgen; Kappel, Jens J.

    2005-01-01

    The principle of non-planar lifting surfaces is applied to the design of modern aircraft wings to obtain better lift to drag ratios. Whereas a pronounced fin or winglet at the wingtip has been developed for aircraft, the application of the nonplanar principle to marine propellers, dealt...

  10. 49 CFR 178.812 - Top lift test.

    Science.gov (United States)

    2010-10-01

    ... devices, so that the hoisting forces are applied vertically, for a period of five minutes; and (ii) Lifted by each pair of diagonally opposite lifting devices, so that the hoisting forces are applied towards... designed until clear of the floor and maintained in that position for a period of five minutes. (2)...

  11. Effect of ship motion on spinal loading during manual lifting

    NARCIS (Netherlands)

    Faber, G.S.; Kingma, I.; Delleman, N.; Dieën, J. van

    2008-01-01

    This study investigated the effects of ship motion on peak spinal loading during lifting. All measurements were done on a ship at sea. In 1-min trials, which were repeated over a wide range of sailing conditions, subjects lifted an 18 kg box five times. Ship motion, whole body kinematics, ground rea

  12. UF{sub 6} cylinder lifting equipment enhancements

    Energy Technology Data Exchange (ETDEWEB)

    Hortel, J.M. [Martin Marietta Energy Systems, Inc., Piketon, OH (United States)

    1991-12-31

    This paper presents numerous enhancements that have been made to the Portsmouth lifting equipment to ensure the safe handling of cylinders containing liquid uranium hexafluoride (UF{sub 6}). The basic approach has been to provide redundancy to all components of the lift path so that any one component failure would not cause the load to drop or cause any undesirable movement.

  13. On the Relationship between Integer Lifting and Rounding Transform

    Directory of Open Access Journals (Sweden)

    R. Vargic

    2007-12-01

    Full Text Available In this paper we analyze the relationship between integer Lifting scheme and Rounding transform as means to compute the wavelet transform in signal processing area. We bring some new results which better describe relationship, reversibility and equivalence of integer lifting scheme and rounding transform concept.

  14. Efficient assessment of exposure to manual lifting using company data

    NARCIS (Netherlands)

    van der Beek, Allard J.; Mathiassen, Svend Erik; Burdorf, Alex

    2013-01-01

    The objective of this study, based on an extensive dataset on manual materials handling during scaffolding, was to explore whether routinely collected company data can be used to estimate exposure to manual lifting. The number of manual lifts of scaffold parts while constructing/dismantling scaffold

  15. Efficient assessment of exposure to manual lifting using company data

    NARCIS (Netherlands)

    Beek, A.J. van der; Mathiassen, S.E.; Burdorf, A.

    2013-01-01

    The objective of this study, based on an extensive dataset on manual materials handling during scaffolding, was to explore whether routinely collected company data can be used to estimate exposure to manual lifting.The number of manual lifts of scaffold parts while constructing/dismantling scaffolds

  16. Effect of ship motion on spinal loading during manual lifting

    NARCIS (Netherlands)

    Faber, G.S.; Kingma, I.; Delleman, N.; Dieën, J. van

    2008-01-01

    This study investigated the effects of ship motion on peak spinal loading during lifting. All measurements were done on a ship at sea. In 1-min trials, which were repeated over a wide range of sailing conditions, subjects lifted an 18 kg box five times. Ship motion, whole body kinematics, ground

  17. Hydraulic Redistribution: A Modeling Perspective

    Science.gov (United States)

    Daly, E.; Verma, P.; Loheide, S. P., III

    2014-12-01

    Roots play a key role in the soil water balance. They extract and transport water for transpiration, which usually represents the most important soil water loss in vegetated areas, and can redistribute soil water, thereby increasing transpiration rates and enhancing root nutrient uptake. We present here a two-dimensional model capable of describing two key aspects of root water uptake: root water compensation and hydraulic redistribution. Root water compensation is the ability of root systems to respond to the reduction of water uptake from areas of the soil with low soil water potential by increasing the water uptake from the roots in soil parts with higher water potential. Hydraulic redistribution is a passive transfer of water through the root system from areas of the soil with greater water potential to areas with lower water potential. Both mechanisms are driven by gradients of water potential in the soil and the roots. The inclusion of root water compensation and hydraulic redistribution in models can be achieved by describing root water uptake as a function of the difference in water potential between soil and root xylem. We use a model comprising the Richards equation for the water flow in variably saturated soils and the Darcy's equation for the water flow in the xylem. The two equations are coupled via a sink term, which is assumed to be proportional to the difference between soil and xylem water potentials. The model is applied in two case studies to describe vertical and horizontal hydraulic redistribution and the interaction between vegetation with different root depths. In the case of horizontal redistribution, the model is used to reproduce the fluxes of water across the root system of a tree subjected to uneven irrigation. This example can be extended to situations when only part of the root system has access to water, such as vegetation near creeks, trees at the edge of forests, and street trees in urban areas. The second case is inspired by recent

  18. Shape Design of Lifting body Based on Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Yongyuan Li

    2010-11-01

    Full Text Available This paper briefly introduces the concept and history of lifting body, and puts forward a new method for the optimization of lifting body. This method has drawn lessons from the die line design of airplane is used to parametric numerical modeling for the lifting body, and extract the characterization of shape parameters as design variables, a combination of lifting body reentry vehicle aerodynamic conditions, aerodynamic heating, volumetric Rate and the stability of performance. Multi-objective hybrid genetic algorithm is adopted to complete the aerodynamic shape optimization and design of hypersonic lifting body vehicle when under more variable and constrained condition in order to obtain the Pareto optimal solution of Common Aero Vehicle shape.

  19. TIEG1对HL-60细胞凋亡及Bcl-2/Bax表达的影响%Influence of TIEG1 on Apoptosis of HL-60 Cells and Expression of Bcl-2/Bax

    Institute of Scientific and Technical Information of China (English)

    姚鲲; 杨莹; 胡荣; 苗苗; 廖爱军; 杨威; 刘卓刚

    2013-01-01

    This study was aimed to investigate the influence of TIEG1 on apoptosis of HL-60 cells and the expression of Bcl-2/Bax.Different concentration of TIEG1 were used to treat HL-60 cells,the cell growth inhibition rate was detected by MTT method.After treating HL-60 cells with 12.03 ng/ml TIEG1,cell apoptosis was detected with flow cytometry.Bcl-2 and Bax was detected with RT-PCR.The results showed that TIEG1 had inhibitory effect on HL-60 cell proliferation,and in time-and dose-dependent manners.The more obvious inhibitory effect was observed in HL-60 cells treated with TIEG1 of 12.03 ng/ml.During the course of cell apoptosis,Bax expression increasied,but Bcl-2 expression decreased(P < 0.05).It is concluded that TIEG1 inhibits HL-60 cell proliferation and induces apoptosis in time and dose-dependent manners.During the course of HL-60 cells apoptosis induced by TIEG1,Bcl-2/Bax are assosciated with HL-60 cell apoptosis induced by TIEG1.%本研究旨在观察TIEG1对HL-60细胞凋亡及Bcl-2/Bax表达的影响.用不同浓度的TIEG1处理HL-60细胞,采用MTT法检测细胞生长抑制率.用12.03 ng/ml TIEG1处理HL-60细胞,以流式细胞术检测细胞凋亡,以RT-PCR方法检测Bcl-2及Bax的表达变化.结果表明,TIEG1对HL-60细胞具有增殖抑制作用,其抑制效应呈时间及剂量依赖性.TIEG1 12.03 ng/ml增殖抑制作用较为明显.在细胞凋亡过程中,Bax表达呈升高趋势,而Bcl-2呈下降趋势(P<0.05).结论:TIEG1可以抑制HL-60细胞增殖,进而诱导其凋亡,且呈时间、剂量依赖性.在TIEG1诱导HL-60细胞凋亡的过程中,Bcl-2/Bax与TIEG1诱导HL-60细胞凋亡相关.

  20. Experimental-based Modelling and Simulation of Water Hydraulic Mechatronics Test Facilities for Motion Control and Operation in Environmental Sensitive Applications` Areas

    DEFF Research Database (Denmark)

    Conrad, Finn; Pobedza, J.; Sobczyk, A.

    2003-01-01

    The paper presents experimental-based modelling, simulation, analysis and design of water hydraulic actuators for motion control of machines, lifts, cranes and robots. The contributions includes results from on-going research projects on fluid power and mechatronics based on tap water hydraulic...... proportional valves and servo actuators for motion control and power transmission undertaken in co-operation by Technical University, DTU and Cracow University of Technology, CUT. The results of this research co-operation include engineering design and test of simulation models compared with two mechatronic...