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Sample records for hybris amicrowave-assisted h

  1. Educational program on HPC technologies based on the heterogeneous cluster HybriLIT (LIT JINR

    Directory of Open Access Journals (Sweden)

    Vladimir V. Korenkov

    2017-12-01

    Full Text Available The article highlights the issues of training personnel for work with high-performance computing systems (HPC, as well as of support of the software and information environment which is necessary for the efficient use of heterogeneous computing resources and the development of parallel and hybrid applications. The heterogeneous computing cluster HybriLIT, which is one of the components of the Multifunctional Information and Computing Complex of JINR, is used as the main platform for training and re-training specialists, as well as for training students, graduate students and young scientists. The HybriLIT cluster is a dynamic, actively developing structure, incorporating the most advanced HPC computing architectures (graphics accelerators, Intel Xeon Phi coprocessors, and also it has a developed software and information environment, which in turn, makes it possible to build educational programs on the up-to-date level, and enables the learners to master both modern computing platforms and modern IT technologies.

  2. CONFIGURACIÓN DEL YO Y POLÍTICAS DE GÉNERO EN LA HYBRIS DE ALICIA GENOVESE

    Directory of Open Access Journals (Sweden)

    Alicia Salomone

    2009-11-01

    Full Text Available Este trabajo tiene por objetivo analizar el poemario La Hybris (2007 de la escritora argentina Alicia Genovese, considerando la configuración del yo lírico y, asimismo, el tipo de política genérico-sexual que éste despliega. En este marco, es relevante revisar los sentidos que asume el juego de intertextualidad con la tragedia griega que propone el discurso del poemario. Ello se relaciona, por una parte, con la necesidad de confrontar un presente que se avizora complejo y confuso desde una tradición cultural que aporta construcciones ideológicas y sensibilidades comunitarias que pueden confrontarse con el propio contexto. Por otro lado, el juego intertextual posibilita dar sustento y legitimidad a una voz lírica que no solo expone la furia de ciertos padecimientos, sino que procura, dificultosamente, encontrar modos para que ese malestar se canalice de modo productivo.This article aims to analyze La Hybris (2009, a poetry book by the Argentine writer Alicia Genovese, considering the configuration of the lyric subject as well as the gender politics developed in the text. In this frame, it is relevant to observe the role of intertextuality, in particular, the dialogue established between the tradition of classic tragedles and the poems' discourses. The hypotesis ofthis work mantains that, referring to Greek tragedy, the poems may confront a present that is perceived both complex and confused. On the other hand, intertextuality functions as a way to give support and legitimacy to a lyric voice that not only aims to expose the fury caused by pain but also aspires to canalize her feelings productively.

  3. Mock Data Challenge for the MPD/NICA Experiment on the HybriLIT Cluster

    Science.gov (United States)

    Gertsenberger, Konstantin; Rogachevsky, Oleg

    2018-02-01

    Simulation of data processing before receiving first experimental data is an important issue in high-energy physics experiments. This article presents the current Event Data Model and the Mock Data Challenge for the MPD experiment at the NICA accelerator complex which uses ongoing simulation studies to exercise in a stress-testing the distributed computing infrastructure and experiment software in the full production environment from simulated data through the physical analysis.

  4. H CHEN

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H CHEN. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  5. + H2

    Indian Academy of Sciences (India)

    (1D. ) + H2 (v = 0, j = 0) →. OH + H is undertaken using the quasiclassical trajectory (QCT) method for the collision energy is in the large length of 1.3 to 43 kcal/mol using Dobbyn and Knowles (DK) surface, and the obtained results are compared with those available from earlier available calculated results on the BR surface ...

  6. H Reactor

    Data.gov (United States)

    Federal Laboratory Consortium — The H Reactor was the first reactor to be built at Hanford after World War II.It became operational in October of 1949, and represented the fourth nuclear reactor on...

  7. Production of H H H and H H V (V =γ ,Z ) at the hadron colliders

    Science.gov (United States)

    Agrawal, Pankaj; Saha, Debashis; Shivaji, Ambresh

    2018-02-01

    We consider the production of two Higgs bosons in association with a gauge boson or another Higgs boson at the hadron colliders. We compute the cross sections and distributions for the processes p p →H H H and H H Z within the standard model. In particular, we compute the gluon-gluon fusion one-loop contributions mediated via heavy quarks in the loop. It is the leading order contribution to p p →H H H process. To the process p p →H H Z , it is next-to-next-to-leading-order (NNLO) contribution in QCD coupling. We also compare this contribution to the next-to-leading-order (NLO) QCD contribution to this process. The NNLO contribution can be similar to NLO contribution at the Large Hadron Collider (LHC), and significantly more at higher center-of-mass energy machines. We also study new physics effects in these processes by considering t t H , H H H , H H H H , H Z Z , and H H Z Z interactions as anomalous. The anomalous couplings can enhance the cross sections significantly. The g g →H H H process is specially sensitive to anomalous trilinear Higgs boson self-coupling. For the g g →H H Z process, there is some modest dependence on anomalous H Z Z couplings.

  8. H-H interactions in Pd

    DEFF Research Database (Denmark)

    Christensen, O. B.; Ditlevsen, Peter; Jacobsen, Karsten Wedel

    1989-01-01

    -medium theory to calculate total energies we show the same tendency for the short-range part of the H-H interaction when two H atoms are squeezed into a single site in Pd or PdH. At longer range (of the order a lattice constant) there is an attractive, lattice-mediated H-H interaction. On the basis...

  9. H2 blockers

    Science.gov (United States)

    Peptic ulcer disease - H2 blockers; PUD - H2 blockers; Gastroesophageal reflux - H2 blockers; GERD - H2 blockers ... H2 blockers are used to: Relieve symptoms of acid reflux, or gastroesophageal reflux disease (GERD). This is a ...

  10. Meningitis - H. influenzae

    Science.gov (United States)

    H. influenzae meningitis; H. flu meningitis; Haemophilus influenzae type b meningitis ... H. influenzae meningitis is caused by Haemophilus influenzae type b bacteria. This illness is not the same ...

  11. Phenylacetylene and H bond

    Indian Academy of Sciences (India)

    ... all resembling H bonds. Non-linear H bonds due to secondary interactions. C-H stretching frequency shows blue shift. Heavy atom distances are longer than the sum of van der Waals radii. Formed a task group through IUPAC to come up with a modern definition of H bond. 15 international experts including Desiraju.

  12. Double electron transfer in H- + H+ collisions

    International Nuclear Information System (INIS)

    Braeuning, H; Helm, H; Briggs, J S; Salzborn, E

    2007-01-01

    Absolute cross sections for double electron transfer in H - + H + collisions have been measured for center-of-mass energies from 0.5 keV to 12 keV. Clear oscillations in the cross section are observed which are in excellent agreement with earlier measurements at lower energies by Brouillard et al (1979) as well as Peart and Dolder (1979). After an oscillation maximum at 3 keV center-of-mass energy the cross section decreases for increasing energy with no indication of further oscillations

  13. H-mode physics

    International Nuclear Information System (INIS)

    Itoh, Sanae.

    1991-06-01

    After the discovery of the H-mode in ASDEX ( a tokamak in Germany ) the transition between the L-mode ( Low confinement mode ) and H-mode ( High confinement mode ) has been observed in many tokamaks in the world. The H-mode has made a breakthrough in improving the plasma parameters and has been recognized to be a universal phenomena. Since its discovery, the extensive studies both in experiments and in theory have been made. The research on H-mode has been casting new problems of an anomalous transport across the magnetic surface. This series of lectures will provide a brief review of experiments for explaining H-mode and a model theory of H-mode transition based on the electric field bifurcation. If the time is available, a new theoretical model of the temporal evolution of the H-mode will be given. (author)

  14. Y H DING

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Y H DING. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  15. Disease: H01835 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available vances in molecular genetics and brain magnetic resonance imaging. NMD include lissencephaly (H00268), heterotopia...See also H00268 Lissencephaly, H00270 Periventricular nodular heterotopia, H00271 Polymicrogyria, H01160 Sch

  16. V H Mulimani

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. V H Mulimani. Articles written in Resonance – Journal of Science Education. Volume 10 Issue 11 November 2005 pp 79-84 Classroom. Loading Effects on Resolution in Thin Layer Chromatography and Paper Chromatography · K Girigowda V H Mulimani.

  17. H S Maiti

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H S Maiti. Articles written in Bulletin of Materials Science. Volume 24 Issue 2 April 2001 pp 197-201. Mechanical properties of glass polymer multilayer composite · A Seal N R Bose S K Dalui A K Mukhopadhyay K K Phani H S Maiti · More Details Abstract Fulltext PDF.

  18. Seed thioredoxin h

    DEFF Research Database (Denmark)

    Hägglund, Per; Finnie, Christine; Yano, Hiroyuki

    2016-01-01

    , for example chloroplastic f- and m-type thioredoxins involved in regulation of the Calvin-Benson cycle. The cytosolic h-type thioredoxins act as key regulators of seed germination and are recycled by NADPH-dependent thioredoxin reductase. The present review on thioredoxin h systems in plant seeds focuses...

  19. H A Ranganath

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. H A Ranganath. Articles written in Resonance – Journal of Science Education. Volume 4 Issue 2 February 1999 pp 48-52 Classroom. Teaching and Learning Genetics with Drosophila · H A Ranganath · More Details Fulltext PDF. Volume 4 Issue 9 September ...

  20. Morrel H Cohen

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Morrel H Cohen. Articles written in Resonance – Journal of Science Education. Volume 15 Issue 6 June 2010 pp 493-495 Article-in-a-Box. Towards a Theoretical Biology: Reminiscences · Morrel H Cohen · More Details Fulltext PDF ...

  1. S H Aravind

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. S H Aravind. Articles written in Resonance – Journal of Science Education. Volume 2 Issue 6 June 1997 pp 89-90 Think It Over. To Find Four Distinct Positive Integers such that the Sum of Any Two of them is a Square · S H Aravind · More Details Fulltext PDF ...

  2. H G Khorana

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. H G Khorana. Articles written in Resonance – Journal of Science Education. Volume 17 Issue 12 December 2012 pp 1174-1197 Classics. Total Synthesis of a Gene · H G Khorana · More Details Fulltext PDF ...

  3. H S Mavi

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H S Mavi. Articles written in Bulletin of Materials Science. Volume 30 Issue 3 June 2007 pp 295-299 Nanomaterials. Raman study on single-walled carbon nanotubes with different laser excitation energies · S S Islam Khurshed Ahmad Shah H S Mavi A K Shaukla S Rath Harsh.

  4. H T Taha

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. H T Taha. Articles written in Sadhana. Volume 35 Issue 2 April 2010 pp 177-193. Effects of nanoscale size dependent parameters on lattice thermal conductivity in Si nanowire · M S Omar H T Taha · More Details Abstract Fulltext PDF. The effects of nanoscale size dependent parameters on lattice ...

  5. H B Singh

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. H B Singh. Articles written in Resonance – Journal of Science Education. Volume 9 Issue 12 December 2004 pp 33-44 General Article. Biosensors · S Chauhan Vibhuti Rai H B Singh · More Details Fulltext PDF ...

  6. H B Muralidhara

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H B Muralidhara. Articles written in Bulletin of Materials Science. Volume 29 Issue 5 October 2006 pp 497-503 Corrosion Studies. Effect of condensation product of glycyl–glycine and furfural on electrodeposition of zinc from sulphate bath · H B Muralidhara Y Arthoba Naik T V ...

  7. H. B. Kiran Kumar

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. H. B. Kiran Kumar. Articles written in Journal of Genetics. Volume 92 Issue 2 August 2013 pp 335-340 Review Article. Search for missing schizophrenia genes will require a new developmental neurogenomic perspective · H. B. Kiran Kumar Christina Castellani Sujit Maiti Richard ...

  8. H B Liu

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. H B Liu. Articles written in Sadhana. Volume 34 Issue 4 August 2009 pp 599-606. Of light, of MEMS: Optical MEMS in telecommunications and beyond · F Chollet H B Liu M Ashraf B Thubthimthong X M Zhang G Hegde A Asundi V M Murukeshan A Q Liu · More Details Abstract Fulltext PDF.

  9. H L Bhat

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H L Bhat. Articles written in Bulletin of Materials Science. Volume 24 Issue 5 October 2001 pp 445-453 Crystal Growth. Growth and characterization of indium antimonide and gallium antimonide crystals · N K Udayashankar H L Bhat · More Details Abstract Fulltext PDF.

  10. Evolved H II regions

    International Nuclear Information System (INIS)

    Churchwell, E.

    1975-01-01

    A probable evolutionary sequence of H II regions based on six distinct types of observed objects is suggested. Two examples which may deviate from this idealized sequence, are discussed. Even though a size-mean density relation of H II regions can be used as a rough indication of whether a nebula is very young or evolved, it is argued that such a relation is not likely to be useful for the quantitative assignment of ages to H II regions. Evolved H II regions appear to fit into one of four structural types: rings, core-halos, smooth structures, and irregular or filamentary structures. Examples of each type are given with their derived physical parameters. The energy balance in these nebulae is considered. The mass of ionized gas in evolved H II regions is in general too large to trace the nebula back to single compact H II regions. Finally, the morphological type of the Galaxy is considered from its H II region content. 2 tables, 2 figs., 29 refs

  11. AGS polarized H- source

    International Nuclear Information System (INIS)

    Kponou, A.; Alessi, J.G.; Sluyters, T.

    1985-01-01

    The AGS polarized H - source is now operational. During a month-long experimental physics run in July 1984, pulses equivalent to 15 μA x 300 μs (approx. 3 x 10 10 protons) were injected into the RFQ preaccelerator. Beam polarization, measured at 200 MeV, was approx. 75%. After the run, a program to increase the H - yield of the source was begun and significant progress has been made. The H - current is now frequently 20 to 30 μA. A description of the source and some details of our operating experience are given. We also briefly describe the improvement program

  12. F/H Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The F/H Laboratory is the largest of the eight laboratories within the SRS Analytical Area Project with over 100,000 square feet of floor space, 20,000 square foot...

  13. Disease: H01671 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available common mental disorders such as Generalized anxiety disorder (GAD), Panic disorder (PD), and Obsessive-comp... See also H01662 Generalized anxiety disorder, H01664 Panic disorder, H01670 Social anxiety disorder, and H0

  14. BNL volume H- source

    International Nuclear Information System (INIS)

    Prelec, K.; Alessi, J.G.

    1991-01-01

    The volume H minus ion source under development at Brookhaven is unique in that it has a toroidal plasma region, which feeds ions into the central extraction region through a conically shaped filter field. In pulsed operation, it produced 25 mA of H minus in a 1 cm 2 aperture, with an electron-to-H minus ratio of ∼ 3. At 19 mA, a normalized, 90% emittance of 0.44 π mm-mrad has been measured. Up to 50 mA has been extracted through a 1.87 cm 2 aperture. Although not designed for steady state operation, up to 6 mA has been extracted d.c. The addition of xenon to the discharge was found to improve the source output by 20--70%. The circular magnetic cusp field geometry was found to be more favorable than radial cusp fields. 4 refs., 5 figs

  15. H0 revisited

    Science.gov (United States)

    Efstathiou, George

    2014-05-01

    I reanalyse the Riess et al. (hereafter R11) Cepheid data using the revised geometric maser distance to NGC 4258 of Humphreys et al. (hereafter H13). I explore different outlier rejection criteria designed to give a reduced χ2 of unity and compare the results with the R11 rejection algorithm, which produces a reduced χ2 that is substantially less than unity and, in some cases, leads to underestimates of the errors on parameters. I show that there are sub-luminous low-metallicity Cepheids in the R11 sample that skew the global fits of the period-luminosity relation. This has a small but non-negligible impact on the global fits using NGC 4258 as a distance scale anchor, but adds a poorly constrained source of systematic error when using the Large Magellanic Cloud as an anchor. I also show that the small Milky Way Cepheid sample with accurate parallax measurements leads to a distance to NGC 4258 that is in tension with the maser distance. I conclude that H0 based on the NGC 4258 maser distance is H0 = 70.6 ± 3.3 km s-1 Mpc-1, compatible within 1σ with the recent determination from Planck for the base six-parameter Λ cold dark matter cosmology. If the H-band period-luminosity relation is assumed to be independent of metallicity and the three distance anchors are combined, I find H0 = 72.5 ± 2.5 km s-1 Mpc-1, which differs by 1.9σ from the Planck value. The differences between the Planck results and these estimates of H0 are not large enough to provide compelling evidence for new physics at this stage.

  16. Magnetically insulated H- diodes

    International Nuclear Information System (INIS)

    Fisher, A.; Bystritskii, V.; Garate, E.; Prohaska, R.; Rostoker, N.

    1993-01-01

    At the Univ. of California, Irvine, the authors have been studying the production of intense H - beams using pulse power techniques for the past 7 years. Previously, current densities of H - ions for various diode designs at UCI have been a few A/cm 2 . Recently, they have developed diodes similar to the coaxial design of the Lebedev Physical Institute, Moscow, USSR, where current densities of up to 200 A/cm 2 were reported using nuclear activation of a carbon target. In experiments at UCI employing the coaxial diode, current densities of up to 35 A/cm 2 from a passive polyethylene cathode loaded with TiH 2 have been measured using a pinhole camera and CR-39 track recording plastic. The authors have also been working on a self-insulating, annular diode which can generate a directed beam of H - ions. In the annular diode experiments a plasma opening switch was used to provide a prepulse and a current path which self-insulated the diode. These experiments were done on the machine APEX, a 1 MV, 50 ns, 7 Ω pulseline with a unipolar negative prepulse of ∼ 100 kV and 400 ns duration. Currently, the authors are modifying the pulseline to include an external LC circuit which can generate a bipolar, 150 kV, 1 μs duration prepulse (similar prepulse characteristic as in the Lebedev Institute experiments cited above)

  17. Meyer, Prof. Kurt H.

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1952 Honorary. Meyer, Prof. Kurt H. Date of birth: 29 September 1883. Date of death: 14 April 1952. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held from ...

  18. H- source developments

    International Nuclear Information System (INIS)

    Allison, P.W.

    1978-01-01

    The design and operation of a Penning discharge, cold cathode, surface plasma H - ion source are described. A high current density, about 2 A/cm 2 , is extracted from the source by putting about 20 keV across the 2 to 2 1 / 2 mm gap

  19. mohammed r h siddiqui

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. MOHAMMED R H SIDDIQUI. Articles written in Journal of Chemical Sciences. Volume 129 Issue 9 September 2017 pp 1469-1481 Regular Aricle. Synthesis, crystallographic characterization, DFT and TD-DFT studies of Oxyma-sulfonate esters · SAIED M SOLIMAN HAZEM A ...

  20. Willis H Carrier

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 2. Willis H. Carrier - Father of Air Conditioning. R V Simha. General Article Volume 17 Issue 2 February 2012 pp 117-138. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/017/02/0117-0138 ...

  1. Disease: H01860 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available GnRH. Hypersecretion of gonadotropins are often associated with pituitary adenomas (H01102) and central precocious puberty...infertility, and loss of some male characteristics. Endocrine disease ... See also H01102 Pituitary adenomas, H00937 Precocious pub...erty, H00255 Hypogonadotropic hypogonadism, and H01700 Hypopituitarism. ICD-10: E23

  2. Evaluering af afdeling H

    DEFF Research Database (Denmark)

    Kjær Minke, Linda; Birkmose, Sofie Meldal

    2016-01-01

    Som led i Kriminalforsorgens flerårsaftale 2013-2016 blev det åbne statsfængsel Søbysøgård i januar 2015 udvidet med 42 lukkede pladser i den nybyggede afdeling H. Nærværende evaluering kortlægger de erfaringer personalet og indsatte har gjort sig i løbet af det første år. Etableringen af den...... lukkede fængselsafdeling H giver en unik mulighed for at følge henholdsvis hvilke faktorer, der bidrager til udvikling af fængselskultur, og hvordan de respektive faktorer influerer på udvikling af fængselskulturen. Evalueringens metoder består af kvalitative og kvantitative metoder såsom dokumentanalyse...

  3. Disease: H01400 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available cts [DS:H00525]; Glutaric acidemia [DS:H00178]; Lysinuric protein intolerance [DS:H00899]; Pyruvate carboxyl...aired by substrate deficiencies assumed cause in various disorders including lysinuric protein intolerance,

  4. Bubbletecture H / Sebastian Duque

    Index Scriptorium Estoniae

    Duque, Sebastian

    2008-01-01

    Osaka lähedal asuvast keskkonnaõppe külastuskeskusest Bubbletecture H. Arhitekt Shuhei Endo. Hoone programm nägi ette kolm peamist ruumidegruppi: auditoorium, raamatukogu-inforuum ning töötubade ala. Hoone koosneb kolmest omavahel seotud sfäärist, välismuljet kujundavad jaapani seedrist puitosad ja terasplaadid, siseskelett on puidust. Interjööris on keskne roll valgusel. Joon.: asendiplaan, 6 vaadet, värv. fotod: 8 vaadet

  5. H2@Scale Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, Mark

    2017-07-12

    'H2@Scale' is a concept based on the opportunity for hydrogen to act as an intermediate between energy sources and uses. Hydrogen has the potential to be used like the primary intermediate in use today, electricity, because it too is fungible. This presentation summarizes the H2@Scale analysis efforts performed during the first third of 2017. Results of technical potential uses and supply options are summarized and show that the technical potential demand for hydrogen is 60 million metric tons per year and that the U.S. has sufficient domestic resources to meet that demand. A high level infrastructure analysis is also presented that shows an 85% increase in energy on the grid if all hydrogen is produced from grid electricity. However, a preliminary spatial assessment shows that supply is sufficient in most counties across the U.S. The presentation also shows plans for analysis of the economic potential for the H2@Scale concept. Those plans involve developing supply and demand curves for potential hydrogen generation options and as compared to other options for use of that hydrogen.

  6. Antifungal properties of wheat histones (H1-H4) and purified wheat histone H1

    Science.gov (United States)

    Wheat (Triticum sp.) histones H1, H2, H3, and H4 were extracted. H1 was further purified. Their activities against fungi with varying degrees of wheat pathogenicity were determined. They included Aspergillus flavus, A. fumigatus, A. niger, F. oxysporum, F. verticillioides, F. solani, F. graminearu...

  7. Disease: H00379 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00379 Mosquito-borne viral encephalitis, including: Japanese encephalitis [DS:H01533]; Western equine... encephalitis [DS:H01534]; Eastern equine encephalitis [DS:H01535]; Australian encephali...0052] (Japanese encephalitis) Western equine encephalitis virus [GN:T40053] (Western equine encephalitis) Eastern equine... encephalitis virus [GN:T40054] (Eastern equine encephalitis) Murray

  8. Disease: H01864 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available (GH) causes acromegaly (H01483) and pituitary gigantism (H01618). They have the same pathogenetic mechanism...nd IGF-I levels ... See also H01483 Acromegaly and H01618 Pituitary gigantism. ICD-1...0: E22.0 MeSH: D000172 D005877 OMIM: 102200 300943 PMID:22584702 ... AUTHORS ... Herder WW ... TITLE ... Familial gigantism

  9. The H boson

    CERN Document Server

    Duplantier, Bertrand; Rivasseau, Vincent

    2017-01-01

    This volume provides a detailed description of the seminal theoretical construction in 1964, independently by Robert Brout and Francois Englert, and by Peter W. Higgs, of a mechanism for short-range fundamental interactions, now called the Brout-Englert-Higgs (BEH) mechanism. It accounts for the non-zero mass of elementary particles and predicts the existence of a new particle - an elementary massive scalar boson. In addition to this the book describes the experimental discovery of this fundamental missing element in the Standard Model of particle physics. The H Boson, also called the Higgs Boson, was produced and detected in the Large Hadron Collider (LHC) of CERN near Geneva by two large experimental collaborations, ATLAS and CMS, which announced its discovery on the 4th of July 2012. This new volume of the Poincaré Seminar Series, The H Boson, corresponds to the nineteenth seminar, held on November 29, 2014, at Institut Henri Po incaré in Paris.

  10. The H IX galaxy survey - II. H I kinematics of H I eXtreme galaxies

    Science.gov (United States)

    Lutz, K. A.; Kilborn, V. A.; Koribalski, B. S.; Catinella, B.; Józsa, G. I. G.; Wong, O. I.; Stevens, A. R. H.; Obreschkow, D.; Dénes, H.

    2018-05-01

    By analysing a sample of galaxies selected from the H I Parkes All Sky Survey (HIPASS) to contain more than 2.5 times their expected H I content based on their optical properties, we investigate what drives these H I eXtreme (H IX) galaxies to be so H I-rich. We model the H I kinematics with the Tilted Ring Fitting Code TiRiFiC and compare the observed H IX galaxies to a control sample of galaxies from HIPASS as well as simulated galaxies built with the semi-analytic model DARK SAGE. We find that (1) H I discs in H IX galaxies are more likely to be warped and more likely to host H I arms and tails than in the control galaxies, (2) the average H I and average stellar column density of H IX galaxies is comparable to the control sample, (3) H IX galaxies have higher H I and baryonic specific angular momenta than control galaxies, (4) most H IX galaxies live in higher spin haloes than most control galaxies. These results suggest that H IX galaxies are H I-rich because they can support more H I against gravitational instability due to their high specific angular momentum. The majority of the H IX galaxies inherits their high specific angular momentum from their halo. The H I content of H IX galaxies might be further increased by gas-rich minor mergers. This paper is based on data obtained with the Australia Telescope Compact Array through the large program C 2705.

  11. The H1 detector

    International Nuclear Information System (INIS)

    Cozzika, G.

    1992-11-01

    The H1 detector presently operating at the HERA e-p collider is described. A general overview of the detector is given with particular emphasis on the calorimeters, the main element of which is a liquid Argon calorimeter enclosed within a large radius solenoid. Calorimetry in the proton direction, close to the beam-pipe is provided by a copper-silicon pad hadronic calorimeter. In the electron direction a lead-scintillator electromagnetic calorimeter closes the solid angle between the rear part of the liquid Argon calorimeter and the beam-pipe. An iron limited streamer tube tail catcher using the return yoke of the solenoid as absorber completes the calorimetry of the detector. The hardware triggers derived from the calorimeters are also described and some performance details of the calorimeters are given

  12. New lanthanide hydrogen phosphites LnH (P03H)2 2H20

    International Nuclear Information System (INIS)

    Durand, J.; Tijani, N.; Cot, L.; Loukili, M.; Rafiq, M.

    1988-01-01

    LnH ((P0 3 H) 2 2H 2 0 is prepared from lanthanide oxide and phosphorous acid with Ln = La, Y, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er or Tm. By thermal gravimetric analysis LnH (P0 3 H) 2 and LnH 2 P 2 0 5 (P0 3 H) 2 are obtained. The three salts are orthorhombic. Parameters and space groups are given for the three salts of each lanthanide. 4 tabs., 13 refs

  13. Charge transfer in H2+-H(1s) collisions

    International Nuclear Information System (INIS)

    Errea, L.F.; Macias, A.; Mendez, L.; Rabadan, I.; Riera, A.

    2005-01-01

    We present an ab initio study of H 2 + +H(1s) collisions at H 2 + impact energies between 0.4 and 50keV. Cross sections are obtained within the sudden approximation for rotation and vibration of the diatomic molecule. We have found that anisotropy effects are crucial to correctly describe this system in this energy range

  14. Stratospheric H2O

    International Nuclear Information System (INIS)

    Ellsaesser, H.W.

    1979-01-01

    Documentation of the extreme aridity (approx. 3% relative humidity) of the lower stratosphere and the rapid decrease of mixing ratio with height just above the polar tropopause (20-fold in the 1st km) was begun by Dobson et al., (1946) in 1943. They recognized that this extreme and persistent aridity must be dynamically maintained else it would have been wiped out by turbulent diffusion. This led Brewer (1949) to hypothesize a stratospheric circulation in which all air enters through the tropical tropopause where it is freeze dried to a mass mixing ratio of 2 to 3 ppM. This dry air then spreads poleward and descends through the polar tropopauses overpowering upward transport of water vapor by diffusion which would otherwise be permitted by the much warmer temperatures of the polar tropopauses. Questions can indeed be raised as to the absolute magnitudes of stratospheric mixing ratios, the effective temperature of the tropical tropopause cold trap, the reality of winter pole freeze-dry sinks and the representativeness of the available observations suggesting an H 2 O mixing ratio maximum just above the tropical tropopause and a constant mixing ratio from the tropopause to 30 to 35 km. However, no model that better fits all of the available data is available, than does the Brewer (1949) hypothesis coupled with a lower stratosphere winter pole, freeze-dry sink, at least over Antarctica

  15. Esophageal pH monitoring

    Science.gov (United States)

    pH monitoring - esophageal; Esophageal acidity test ... Esophageal pH monitoring is used to check how much stomach acid is entering the esophagus. It also checks how well the acid is cleared downward into the ...

  16. Disease: H00590 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ch CMD (UCMD). Muscular dystrophy-dystroglycanopathy type A [DS:H00120] includes Walker-Warburg syndrome (WW...ner HG, Guicheney P, van Bokhoven H ... TITLE ... The expanding phenotype of POMT1 mutations: from Walker

  17. H1 at HERA Exhibition

    CERN Multimedia

    2000-01-01

    H1 is one of the two large detectors installed at HERA, the first electron-proton accelerator, located at DESY in Hamburg. The H1 collaboration regroups physicists from 32institutes of 11countries all over the world.

  18. Disease: H00228 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00228 Thalassemia, including: Alpha thalassemia; Beta thalassemia; Alpha thalasse...mia, X-linked (ATRX) [DS:H01752] Thalassemia is the most common hereditary blood disease caused by mutation

  19. Disease: H01395 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01395 POLG related disorders, including: Alpers syndrome [DS:H01389]; Childhood myocerebro...erlapping symptoms and signs; and range from a rapidly fatal infantile cerebrohepatic disease to a progressi

  20. Disease: H00577 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available syndrome (H01460), Lennox-Gastaut syndrome (H01813), Dravet syndrome (H01818), Epilepsy with myoclonic-astat...ileptic encephalopathy (H00606), and other symptomatic generalized epilepsies. Congenital disorder; Epilepsy... ... Other symptomatic generalized epilepsies include Epilepsy, hearing loss, an...and Hypomagnesemia, seizures, and mental retardation (HOMGSMR). The International League Against Epilepsy (I...tional League Against ... Epilepsy. ... JOURNAL ... Epilepsia 30:389-99 (1989) DOI:10.1111/j.1528-1157.1989.tb05316

  1. Disease: H00509 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Graul-Neumann LM, van Hagen JM, van Hest L, Horovitz D, Melki J, Partsch CJ, Plauchu H, Rajab...H, van Hest L, Lund AM, Michaud J, Oley C, Patel C, Rajab A, Skidmore DL, Stewart H, Tauber M, Munnich A, Co

  2. Viva the h-index

    OpenAIRE

    Waaijers, Leo

    2011-01-01

    In their article 'The inconsistency of the h-index' Ludo Waltman and Nees Jan van Neck give three examples to demonstrate the inconsistency of the h-index. As will be explained, a little extension of their examples just illustrate the opposite, a stable feature of the h-index. For starting authors it, the h-index that is, focusses on the number of articles; for experienced authors its focus shifts towards the citation scores. This feature may be liked or not but does not make the h-index an i...

  3. Objective determination of pH thresholds in the analysis of 24 h ambulatory oesophageal pH monitoring

    NARCIS (Netherlands)

    Weusten, B. L.; Roelofs, J. M.; Akkermans, L. M.; vanBerge-Henegouwen, G. P.; Smout, A. J.

    1996-01-01

    In 24 h oesophageal pH monitoring, pH 4 is widely but arbitrarily used as the threshold between reflux and non-reflux pH values. The aim of the study was to define pH thresholds objectively, based on Gaussian curve fitting of pH frequency distributions. Single-channel 24 h oesophageal pH monitoring

  4. H0 precessor computer code

    International Nuclear Information System (INIS)

    van Dyck, O.B.; Floyd, R.A.

    1981-05-01

    A spin precessor using H - to H 0 stripping, followed by small precession magnets, has been developed for the LAMPF 800-MeV polarized H - beam. The performance of the system was studied with the computer code documented in this report. The report starts from the fundamental physics of a system of spins with hyperfine coupling in a magnetic field and contains many examples of beam behavior as calculated by the program

  5. Disease: H01565 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01565 Wernicke encephalopathy; Wernicke-Korsakoff syndrome Wernicke encephalopathy...linolysis. When Wernicke encephalopathy is suspected, treatment with high-dose parenteral thiamine (vitamin ...at an association exists between Wernicke encephalopathy and genetic polymorphisms in the thiamine transport...3 ... AUTHORS ... Yahia M, Najeh H, Zied H, Khalaf M, Salah AM, Sofienne BM, Laidi B, Hamed J, Hayenne M ... TITLE ... Wernicke's encephalo...pathy: A rare complication of hyperemesis gravidarum. ... JOURNAL ... Anaesth Crit Care

  6. Disease: H00505 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00505 FGFR3-related short limb skeletal dysplasias, including: Achondroplasia [DS...:H01749]; Hypochondroplasia; Thanatophoric dysplasia [DS:H01750]; Severe achondroplasia with developmental d...elay and acanthosis nigricans (SADDAN) FGFR3-related short limb skeletal dysplasias are a group of dwarfisms...tions by disrupting endochondral bone growth. Skeletal dysplasia FGFR3 [HSA:2261] [KO:K05094] ... ICD-10: ...HORS ... Cohen MM Jr ... TITLE ... Some chondrodysplasias with short limbs: molecular

  7. Disease: H00783 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00783 Febrile seizures, including: Febrile convulsions; Generalized epilepsy with... febrile seizure plus (GEFS+); Dravet syndrome/ Severe myoclonic epilepsy in infancy [DS:H01818] Febrile sei... represent the most common form of childhood seizures. Generalized epilepsy with ...febrile seizures plus (GEFS+) is a familial epilepsy syndrome with a spectrum of phenotypes including FS. Severe epilepsy...Weber YG, Lerche H ... TITLE ... Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy

  8. Discover 4-H Clubs: The Essential Resource for 4-H

    Science.gov (United States)

    MacArthur, Stacey; Nelson, Cindy; Brower, Naomi; Memmott, Margie; Peterson, Gaelynn

    2016-01-01

    Obstacles facing new 4-H volunteers include time constraints and difficulty finding project-specific information, resources, and opportunities available for club members. As a solution to these obstacles and an aid for assisting volunteers in becoming confident in delivering information to youth, content experts produced Discover 4-H Clubs, a…

  9. Disease: H00169 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00169 Ocular albinism; Ocular albinism, type I (OA1); Waardenburg syndrome, type ...ia, nystagmus, translucent irides, strabismus, hypermetropic refractive errors. Waardenburg syndrome type II

  10. Disease: H01125 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available h striking anisopoikilocytosis with red cell fragmentation and microspherocytes. Erythrocytes from most HPP patients exhibit qualitat...ive and quantitative abnormalities of the erythrocyte me

  11. Disease: H00253 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00253 Neurohypophyseal diabetes insipidus (NPDI); Central Diabetes Insipidus Cent...700 PMID:16713494 ... AUTHORS ... Christensen JH, Rittig S ... TITLE ... Familial neurohypophyseal diabetes insipi

  12. Disease: H01652 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01652 Seborrheic dermatitis Seborrheic Dermatitis (SD) is a common inflammatory d...ption, pathogen) ... AUTHORS ... Borda LJ, Wikramanayake TC ... TITLE ... Seborrheic Dermatitis

  13. Ebrotidina: nuevo antagonista H2

    Directory of Open Access Journals (Sweden)

    Noel Padrón Pérez

    1999-01-01

    Full Text Available Se realizó una revisión bibliográfica sobre un nuevo antagonista H2, la ebrotidina, que exhibe ventajas con respecto a otros medicamentos antisecretores. Las propiedades gastroprotectoras y la actividad anti H. pylori del fármaco, en el tratamiento de la enfermedad péptica ulcerosa, se mencionan en el presente trabajo.A bibliographic review on the new H2 antagonist, ebrotidine, that presents advantages in comparison with other antisecretory drugs, is made. The gastroprotective properties and the anti H. pylori activity of the drug in the treatment of peptic ulcer are mentioned in this paper.

  14. Plasma neutralizer for H- beams

    International Nuclear Information System (INIS)

    Grossman, M.W.

    1977-01-01

    Neutralization of H - beams by a hydrogen plasma is discussed. Optimum target thickness and maximum neutralization efficiency as a function of the fraction of the hydrogen target gas ionized is calculated for different H - beam energies. Also, the variation of neutralization efficiency with respect to target thickness for different H - beam energies is computed. The dispersion of the neutralized beam by a magnetic field for different energies and different values of B . z is found. Finally, a type of plasma jet is proposed, which may be suitable for a compact H - neutralizer

  15. Disease: H01440 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01440 Acute necrotizing ulcerative gingivitis; Vincent's gingivitis; Vincent angina...; Trench mouth Acute necrotizing ulcerative gingivitis, also known as Trench mouth, Vincent angina and Vin

  16. Ophthalmic antihistamines and H1-H4 receptors.

    Science.gov (United States)

    Wade, Laurie; Bielory, Leonard; Rudner, Shara

    2012-10-01

    Antihistamines exert pharmacologic effects by binding to four histamine receptors (H1-H4) at different affinities, producing variable effects depending on the receptor they predominantly bind to. This review's purpose is to determine the relative potency of antihistamines by comparing their binding affinities to these receptors. Studies on binding affinities of antihistamines to histamine receptors were reviewed and the dissociation constant for inhibitor binding (Ki) analyzed to determine the most and least potent antihistamine for each receptor. We retrieved the binding affinities for nineteen antihistamines. For H1 receptors, pyrilamine exhibited the highest affinity (Ki = 0.8 nM), and thioperamide the lowest (Ki = 280, 000 nM). For H2 receptors, ranitidine exhibited the highest affinity (Ki = 187 nM), and olopatadine the lowest (Ki = 100 ,000 nM). For the recently discovered H3 and H4 receptors, thioperamide exhibited the highest affinity (Ki = 1.1 nM), and olopatadine exhibited the lowest (Ki = 79 ,400 nM), to H3. Data on binding affinities to the H4 receptor exist for: ketotifen, pheniramine, ranitidine, cimetidine and thioperamide. Of these, thioperamide exhibited the highest affinity (Ki = 27 nM), whereas cimetidine and ranitidine exhibited the lowest affinity (Ki = >10, 000 nM) for H4 receptors. This review summarizes the relative potency of antihistamines based on their binding affinities to the four histamine receptors. Although data on binding affinities of antihistamines to the H4 receptor are sparse, it is apparent that further research on these histamine subtypes may open new venues for more direct treatment with a higher therapeutic efficacy on allergic disorders including those affecting the ocular surface.

  17. Impact of a future H

    NARCIS (Netherlands)

    Popa, M.E.; Segers, A.J.; Denier van der Gon, H.A.C.; Krol, M.C.; Visschedijk, A.J.H.; Schaap, M.; Röckmann, T.

    2015-01-01

    Hydrogen (H2) is being explored as a fuel for passenger vehicles; it can be used in fuel cells to power electric motors or burned in internal combustion engines. In order to evaluate the potential influence of a future H2-based road transportation on the regional air quality

  18. Impact of a future H

    NARCIS (Netherlands)

    Popa, M.E.; Segers, A.J.; Denier van der Gon, H.A.C.; Krol, M.C.; Visschedijk, A.J.H.; Schaap, M.; Röckmann, T.

    2015-01-01

    Hydrogen (H2) is being explored as a fuel for passenger vehicles; it can be used in fuel cells to power electric motors or burned in internal combustion engines. In order to evaluate the potential influence of a future H2-based road transportation on the regional air quality in Europe, we

  19. Disease: H01377 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01377 Mitchell-Riley syndrome Mitchell-Riley syndrome is a neonatal diabetes synd...rome that involves abnormalities of the anterior gut as well as diabetes. Patients with this syndrome are ty...aniels M, Liu X, Paz VP, Ye H, Highland HM, Hanis CL, Greeley SA ... TITLE ... Neonatal diabetes, gallbladder

  20. Disease: H01534 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01534 Western equine encephalitis Western equine encephalitis virus (WEEV) is an ..., and death. Infectious disease ... Western equine encephalitis virus [GN:T40053] ... See also H00379 ... Mosquito...eaver SC ... TITLE ... Structure of the recombinant alphavirus Western equine encep

  1. Disease: H00399 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00399 Avian influenza; Bird flu; H5N1 flu Influenza A virus exhibits the broad host spectrum (birds..., humans, other mammals) and viruses that have been isolated from birds are termed avian i...nfluenza viruses. Avian influenza viruses can cross the species barrier into humans via direct contact with infected birds

  2. Disease: H01717 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available . Many cases of optic neuritis are associated with multiple sclerosis or neuromyelitis optica or can occur i...feron beta [DR:D04554 D00746] Glatiramer acetate [DR:D04318] See also H01490 Multiple sclerosis and H01491 Neuromyelitis optica

  3. H- charge exchange injection systems

    International Nuclear Information System (INIS)

    Ankenbrandt, C.; Curtis, C.; Hojvat, C.; Johnson, R.P.; Owen, C.; Schmidt, C.; Teng, L.; Webber, R.C.

    1980-01-01

    The techniques and components required for injection of protons into cyclic accelerators by means of H - charge exchange processes are reviewed, with emphasis on the experience at Fermilab. The advantages of the technique are described. The design and performance of the system of injection of H - ions into the Fermilab Booster are detailed. (Auth.)

  4. Disease: H00793 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available k R, Kirwan M, Dokal I ... TITLE ... Mutations in C16orf57 and normal-length telomeres unify a subset of patients with dyskeratosis...B1 [HSA:79650] ... Dyskeratosis congenita (H00507) and Rothmund-Thomson syndrome (H00296) display clinical ...tropenia. It has been reported mutations in USB1 cause this condition. Skin and connective tissue disease US

  5. Disease: H00332 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00332 Listeriosis Listeriosis is a severe foodborne infection with high case fata...LE ... Listeria monocytogenes: food-borne pathogen and hygiene indicator. ... JOURN...u H, Schlundt J ... TITLE ... Quantitative risk assessment of Listeria monocytogenes in ready-to-eat foods: th

  6. Disease: H01208 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available d that a homozygous mutation in SPATA16 was associated with male infertility in h...uman globozoospermia. It has also been reported that a recurrent deletion of DPY19L2 causes infertility in m...hoven H, Viville S ... TITLE ... Homozygous mutation in SPATA16 is associated with male infertility in human g

  7. The pH Game.

    Science.gov (United States)

    Chemecology, 1996

    1996-01-01

    Describes a game that can be used to teach students about the acidity of liquids and substances around their school and enable them to understand what pH levels tell us about the environment. Students collect samples and measure the pH of water, soil, plants, and other natural material. (DDR)

  8. Van der Waals bond in dimers: H2Ne, H2Ar, H2Kr

    International Nuclear Information System (INIS)

    Waaijer, M.

    1981-01-01

    The H 2 -inert gas dimers H 2 X, and particularly H 2 Ne, H 2 Ar and H 2 Kr, form the subject of this thesis and are loosely bound van der Waals complexes, which is reflected in the low number of bound states and the small anisotropic interaction. The H 2 X dimers studied are formed in a supersonic nozzle expansion, in which the internal energy is converted into the macroscopic flow energy, establishing an internal temperature drop to 3 K, which favours dimer formation. Because of this cooling the H 2 X dimers relax to the lowest rotational states. The hyperfine transitions have been measured using magnetic beam resonance and yield information about the isotropic as well as the anisotropic intermolecular potential in the range between the classical turning points and in the adjacent part of the repulsive branch. The sensitivity of the method is very high and slight changes in the intermolecular potential cause significant effects. The analysis of the measured hyperfine transitions incorporates all interacting states of the molecule, bound as well as unbound (continuum) states. For H 2 Ne, which is the best studied H 2 -inert gas system from the experimental point of view, the author succeeded in establishing an intermolecular potential, that provides a solid ground for comparison with future ab initio calculations. (Auth.)

  9. Dust in H II regions

    International Nuclear Information System (INIS)

    Isobe, S.

    1977-01-01

    Several pieces of evidence indicate that H II regions may contain dust: 1) the continuum light scattered by dust grains (O'Dell and Hubbard, 1965), 2) thermal radiation from dust grains at infrared wavelengths (Ney and Allen, 1969), 3) the abnormal helium abundance in some H II regions (Peimbert and Costero, 1969), etc. Although observations of the scattered continuum suggest that the H II region cores may be dust-free, dust grains and gas must be well mixed in view of the infrared observations. This difficulty may be solved by introducing globules with sizes approximately 0.001 pc. These globules and the molecular clouds adjacent to H II regions are the main sources supplying dust to H II regions. (Auth.)

  10. Resonant charge exchange for H-H+ in Debye plasmas

    Science.gov (United States)

    Laricchiuta, Annarita; Colonna, Gianpiero; Capitelli, Mario; Kosarim, Alexander; Smirnov, Boris M.

    2017-11-01

    The dynamics of resonant charge exchange in proton-hydrogen collisions embedded in plasma is investigated in the framework of the asymptotic approach, modified to account for the effect of Debye-Hückel screening in particle interactions. The cross sections exhibit a marked dependence on the Debye length in regimes of severe plasma confinement. Processes involving excited states H( n)-H+ are also discussed.

  11. Disease: H00422 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ria (AGU) [DS:H00145]; Fucosidosis [DS:H00141]; Schindler/ Kanzaki disease [DS:H00146] Glycoproteinoses is a...cosidase [HSA:2517] [KO:K01206] (Schindler/ Kanzaki) NAGA; alpha-N-acetylgalactosaminidase [HSA:4668] [KO:K0...PD:C00270] (alpha, beta-Mannosidosis, AGU, Fucosidosis, Schindler/ Kanzaki) Urine oligosaccharides, Vacuolat...g loss and mental retardation. (Fucosidosis) Type 1: a severe form. Type2: a mild form. (Schindler/ Kanzaki) Type1 (Schindle...lpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease). ... JOURNAL ... J Hum Genet 49:1-8 (2004) DOI:10.1007/s10038-003-0098-z ...

  12. Extinction of H II regions

    International Nuclear Information System (INIS)

    Israel, F.P.; Kennicutt, R.C.

    1980-01-01

    Visual extinction of H II regions in nine nearby galaxies as derived from the ratio of the radio continuum emission to H-alpha emission is systematically larger than visual extinction deduced from the Balmer lines alone, if one assumes a value Av/E(B-V) 3. An optically-limited sample of about 30 extragalactic H II regions has a mean extinction of 1.7 m in the visual while about 1.2 m is not seen in the reddening of the Balmer lines. Both reddening and extinction decreases with increasing galactic radius, at least for M33 and M101

  13. Disease: H01683 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01683 Disorders of antidiuretic hormone (ADH) secretion Water imbalance is common...ous pathologic and iatrogenic causes for water imbalance, the most troublesome being disorders of antidiuret

  14. Disease: H01584 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01584 IgA vasculitis; Henoch-Schonlein purpura Henoch-Schonlein purpura (HSP) is ...the most common systemic small vessel vasculitis in childhood with clinical characteristics of non-thrombocy

  15. Disease: H01339 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01339 Asymptomatic bacteriuria The term asymptomatic bacteriuria is generally used to distinguish coloniza...tion from infection and to emphasize that the presence of bacteria at mucosal surfa

  16. Disease: H00759 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00759 Waardenburg syndrome (WS) Waardenburg syndrome (WS) is a rare autosomal dom...M, Marlin S, Bondurand N ... TITLE ... Review and update of mutations causing Waardenburg syndrome. ... JOURNAL

  17. Disease: H01187 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available e been found to produce Waardenburg syndrome type 2 (WS2) [DS:H00169], which also... the MITF (microphthalmia associated transcription factor) gene. Mutations in other regions of this gene hav

  18. Disease: H01505 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01505 Inclusion body myositis Inclusion body myositis (IBM) is the most frequent ...imachkie MM, Barohn RJ ... TITLE ... Inclusion body myositis. ... JOURNAL ... Neurol Clin 32:629-46, vii (2014) DO

  19. Disease: H01031 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01031 Orthostatic intolerance (OI); Postural tachycardia syndrome (POTS) Orthostatic intolerance...rdan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D ... TITLE ... Orthostatic intolerance

  20. Disease: H00899 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00899 Lysinuric protein intolerance (LPI) Lysinuric protein intolerance (LPI) is ...e) ... AUTHORS ... Sperandeo MP, Andria G, Sebastio G ... TITLE ... Lysinuric protein intolerance: update and exte

  1. Disease: H00642 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Be...32 OMIM: 149730 PMID:16501574 (gene) ... AUTHORS ... Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G,

  2. Disease: H01258 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Epilepsy is one of th...BK channel causes this syndrome. Nervous system disease; Epilepsy KCNMA1 [HSA:3778] [KO:K04936] ... ICD-10

  3. Disease: H01775 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01775 PCDH19-related epilepsy syndrome; Early infantile epileptic encephalopathy 9; Epilepsy...ded protocadherin 19 (PCDH19) cause this disorder, and are confirmatory for the diagnosis. Congenital disorder; Epilepsy

  4. Disease: H00611 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00611 IRF6-related disorders, including: Popliteal pterygium syndrome (PPS); Van der Woud...e syndrome (VWS) Popliteal pterygium syndrome (PPS) and Van der Woude syndrome (VWS) are autosomal d

  5. Disease: H01919 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01919 Proud syndrome Proud syndrome is a syndromic X-linked mental retardation, c...nse mutations in the homeobox domain cause malformation syndromes such as Proud syndrome. Developmental diso

  6. Urine pH test

    Science.gov (United States)

    ... urine test Male urinary tract References Bose A, Monk RD, Bushinsky DA. Kidney stones. In: Melmed S, Polonsky ... and its influence on urine pH. J Am Diet Assoc . 1995;95(7):791-797. PMID: 7797810 ...

  7. Disease: H01879 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01879 Wiedemann-Steiner syndrome; Alazami-Yuan syndrome Wiedemann-Steiner Syndrom...a N, Matsumoto N ... TITLE ... Delineation of clinical features in Wiedemann-Steiner syndrome caused by KMT2A

  8. Disease: H01777 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available pment frequently become evident during the first year of life. SJS type 2, also known as Stuve-Wiedema...n allelic disorder with a more severe phenotype. See also H00462 Stuve-Wiedemann

  9. Disease: H00540 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00540 Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodefici...ency (OLEDAID); Ectodermal dysplasia, anhidrotic, with immunodeficiency, osteopetrosis, and lymphedema A rar...e X-linked recessive syndrome 'Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficien

  10. Disease: H01909 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available hypoglycemia with hemihypertrophy (HIHGHH) is characterized by hemihypertrophy without any other features of Beckwith-Wiedema...ted metabolic disease AKT2 [HSA:208] [KO:K04456] ... See also H00713 Beckwith-Wiedema

  11. Disease: H00711 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ergrowth disease Beckwith-Wiedemann syndrome [DS:H00713] present two genetically and clinically opposite cli...ilver-Russell and Beckwith-Wiedemann syndromes: opposite (epi)mutations in 11p15

  12. Disease: H01911 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01911 Syndromic autosomal recessive mental retardation Mental retardation (MR) is a neurodevelopmental... S, Rich P, Qualmann B, Hurles ME, Kessels MM, Crosby AH ... TITLE ... Mutations in KPTN cause macrocephaly, neurodevelopmental

  13. Disease: H01952 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ies, and myopathy with exercise intolerance. Inherited metabolic disease ALDOA [H...ne, which encodes the red cell aldolase. The typical presentation is hemolytic anemia, neurologic abnormalit

  14. Disease: H00897 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ) ... AUTHORS ... Akizu N, Cantagrel V, Schroth J, Cai N, Vaux K, McCloskey D, Naviaux RK, Van Vleet J, Fenstermaker AG, Silhavy JL, Sche...liga JS, Toyama K, Morisaki H, Sonmez FM, Celep F, Oraby

  15. Disease: H00299 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00299 Shigellosis; Bacillary dysentery Shigellosis (bacillary dysentery) is a food...t and bloody diarrhea, and tenesmus. Transmission usually occurs via contaminated food and water or through

  16. Disease: H01579 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01579 Congenital symmetric circumferential skin creases; Kunze-Riehm syndrome; Michelin tire baby... syndrome Congenital symmetric circumferential skin creases, also known as Michelin tire baby

  17. Disease: H01330 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01330 Brazilian purpuric fever (BPF) Brazilian purpuric fever (BPF), which is cau...on of Haemophilus influenzae biogroup aegyptius (Haemophilus aegyptius) strains associated with Brazil

  18. Disease: H00445 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00445 Osteoarthritis with mild chondrodysplasia The disease is characterized by a...m D, Ferguson R, Moskowitz R ... TITLE ... Osteoarthritis in children associated with a mutation in the type I

  19. Disease: H00317 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00317 Melioidosis Melioidosis is an infection caused by the gram-negative soil-dw...elling bacillus Burkholderia pseudomallei. It predominantly affects people in regular contact with soil and

  20. Disease: H00316 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00316 Glanders Glanders is an infectious disease of equines that can be transmitt...ent of glanders is Burkholderia mallei, a gram-negative aerobic bacterium. In equines and humans, B. mallei

  1. Disease: H01600 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01600 Parkinsonian syndrome Parkinsonian syndromes (PS) are multisystemic disease...6 (description, drug) ... AUTHORS ... Williams DR, Litvan I ... TITLE ... Parkinsonian ...MID:15033141 (description) ... AUTHORS ... Pezzoli G, Canesi M, Galli C ... TITLE ... An overview of parkinsonian

  2. Disease: H01343 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available erobacteriaceae, is known as an emerging phytopathogen infecting a wide range of im... H01343 Pantoea ananatis infection Pantoea ananatis, a gram-negative, motile rod belonging to the family Ent

  3. Disease: H00301 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00301 Klebsiella infection Klebsiella is a gram-negative bacterium of Enterobacteriaceae...pta N, Limbago BM, Patel JB, Kallen AJ ... TITLE ... Carbapenem-resistant Enterobacteriaceae: epidemiology and

  4. Disease: H00979 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00979 Caudal regression syndrome and Sirenomelia Caudal dysgenesis and sirenomelia...nitourinary anomalies. The most severe end of this spectrum is known as sirenomelia..., Bower C ... TITLE ... Caudal dysgenesis and sirenomelia-single centre experience

  5. Disease: H01832 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01832 Lenz-Majewski syndrome; Lenz-Majewski hyperostotic dwarfism Lenz-Majewski s...yndrome (LMS), also known as Lenz-Majewski hyperostotic dwarfism, is an extremely rare syndrome characterize

  6. Disease: H01670 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01670 Social anxiety disorder; Social phobia Social anxiety disorder (SAD) is the...8374843 (description, drug) ... AUTHORS ... Stein MB, Stein DJ ... TITLE ... Social anxiety disorder. ... JOURNAL ...

  7. Disease: H00631 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Rodriguez MC, Clark D, Hakonarson H, Halbach S, Michelis LD, Rampuria A, Rossier ...RS ... Deardorff MA, Wilde JJ, Albrecht M, Dickinson E, Tennstedt S, Braunholz D, Monnich M, Yan Y, Xu W, Gil-

  8. Disease: H01657 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available standard treatment for SRNS. It has been reported that additional rituximab treatment combined with convent...287] Mizoribine [DR:D01392] Rituximab [DR:D02994] See also H00626 Focal segmental

  9. Disease: H00841 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available drome (BVVLS) [DS:H01903]; Fazio-Londe disease Infantile progressive bulbar palsy is a rare neurological disorder that occurs in chil...dren. Infantile progressive bulbar palsy presents as following two forms. The Brown

  10. H2@Scale Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Pivovar, Bryan

    2017-03-31

    Final report from the H2@Scale Workshop held November 16-17, 2016, at the National Renewable Energy Laboratory in Golden, Colorado. The U.S. Department of Energy's National Renewable Energy Laboratory hosted a technology workshop to identify the current barriers and research needs of the H2@Scale concept. H2@Scale is a concept regarding the potential for wide-scale impact of hydrogen produced from diverse domestic resources to enhance U.S. energy security and enable growth of innovative technologies and domestic industries. Feedback received from a diverse set of stakeholders at the workshop will guide the development of an H2@Scale roadmap for research, development, and early stage demonstration activities that can enable hydrogen as an energy carrier at a national scale.

  11. Disease: H01798 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01798 Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) Autos...omal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is an inherited autoimmune uveitis and vitr... ... Secondary glaucoma in CAPN5-associated neovascular inflammatory vitreoretinopathy. ... JOURNAL ... Clin Ophtha

  12. Disease: H00856 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available on, gene) ... AUTHORS ... Rossor AM, Kalmar B, Greensmith L, Reilly MM ... TITLE ... The distal hereditary motor n...oylan KB, Reilly MM, Greensmith L, Singleton AB, Harms MB, Rossor AM, Houlden H ... TITLE ... A dominant mutat

  13. Disease: H01731 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01731 Fragile X tremor/ataxia syndrome (FXTAS) Fragile X tremor/ataxia syndrome (...0) in the fragile X mental retardation 1 (FMR1) gene. Common manifestations of FXTAS are progressive intention tremor

  14. Disease: H01404 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01404 Punctate palmoplantar keratoderma (PPKP), including: Brauer-Buschke-Fischer disease; Porokeratosis...ypes; PPKP1 (Brauer-Buschke-Fischer disease), PPKP2 (porokeratosis punctata palmaris et plantaris), and PPKP

  15. Disease: H00370 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00370 Progressive multifocal leukoencephalopathy (PML) Progressive multifocal leukoencephalopathy...PMID:15167073 (description) ... AUTHORS ... Koralnik IJ ... TITLE ... New insights into progressive multifocal leukoencephalopathy. ... JOURNAL ... Curr Opin Neurol 17:365-70 (2004) ...

  16. Disease: H00874 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00874 Leukoencephalopathy with dystonia and motor neuropathy Leukoencephalopathy ...sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy. ... JOURNAL ... Am J Hum Genet 78:1046-52 (2006) DOI:10.1086/503921

  17. Disease: H00361 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00361 Malaria Malaria is the most important threatening infectious disease, infec...es occur in sub-Saharan Africa. Malaria is caused by Plasmodium parasites that are transmitted through the b

  18. Disease: H01874 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01874 Cronkhite-Canada syndrome Cronkhite-Canada syndrome (CCS) is a rare noninhe...MID:22675285 ... AUTHORS ... Sweetser S, Boardman LA ... TITLE ... Cronkhite-Canada syndrome: an acquired conditio

  19. Disease: H01794 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01794 Genitopatellar syndrome (GPS) Genitopatellar syndrome (GPS) is a rare disorder in which patel...f the gene encoding the histone acetyltransferase KAT6B cause Genitopatellar synd

  20. Disease: H00655 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00655 McLeod syndrome McLeod syndrome is an X-linked multisystem disorder including the CNS (chorea, epile...psy), the PNS (axonal polyneuropathy), and the blood cells (acanthocytosis of the e

  1. Disease: H01048 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01048 Liver fluke disease; Fascioliasis Fascioliasis is a foodborne zoonotic dise...ription) ... AUTHORS ... Mas-Coma S, Bargues MD, Valero MA ... TITLE ... Fascioliasis and other plant-borne tremat

  2. Disease: H01662 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01662 Generalized anxiety disorder; Anxiety neurosis Generalized anxiety disorder is a persistent...e symptoms include generalised and persistent excessive anxiety and a combination of various psychological a

  3. Disease: H00815 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00815 Hyperpigmentation, cutaneous, with hypertrichosis, hepatosplenomegaly, heart anomalies, hearing...omalies, sensorineural hearing loss, hypogonadism, short stature, and hyperglycem...haracterized by the association of cutaneous hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart an

  4. Disease: H00581 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00581 Alport syndrome Alport syndrome is a hereditary hematuric nephropathy with frequent hearing...rogressive nephritis and hearing impairment. Kidney disease (autosomal) COL4A3 [HSA:1285] [KO:K06237] (autos

  5. Disease: H01372 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01372 Vitiligo Vitiligo is a common, multifactorial, polygenic disease in which a...953 ... PMID:22835073 ... AUTHORS ... Colucci R, Lotti T, Moretti S ... TITLE ... Vitiligo: an update on current phar

  6. Disease: H00490 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00490 Diaphyseal dysplasia with anemia (Ghosal) Diaphyseal dysplasia with anemia ...(Ghosal) is characterized by increased bone density associated with myelophthisic anemia. Mutation in TBXAS1

  7. Disease: H00920 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00920 Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial ...hyperostosis Patients with this disease suffer from exocrine pancreatic insufficiency, dyserythropoietic anemia...eleg O ... TITLE ... Exocrine pancreatic insufficiency, dyserythropoeitic anemia, a

  8. Disease: H01214 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01214 Rh-null hemolytic anemia (RHN); Rh-deficiency syndrome Rh (Rhesus) null hemolytic anemia...varying degree of hemolytic anemia and spherostomatocytosis. The Rh protein family comprises Rh50 glycoprote

  9. Disease: H01196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01196 Hypochromic microcytic anemia Hypochromic microcytic anemia has been associ...hereas mutations impairing NRAMP2 function cause a form of congenital hypochromic microcytic anemia. Hematol

  10. Disease: H01328 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01328 Aspergillosis Pulmonary aspergillus infections can be classified based on c... ... ICD-10: B44 MeSH: D001228 MedlinePlus: 001326 PMID:25135079 ... AUTHORS ... Warris A ... TITLE ... The biology of pulmonary aspergillus

  11. Disease: H00618 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00618 Amelogenesis imperfecta hypoplastic-hypomaturation with taurodontism (AIHHT) Amelogenesis...t trait. Mouth and dental disease DLX3 [HSA:1747] [KO:K09315] ... Amelogenesis imperfecta and trichodentoos

  12. Disease: H01513 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01513 Retinoblastoma The retinoblastoma is an eye tumor of childhood that arises ...in the retina and represents the most common intraocular malignancy of infancy and childhood. Tumor formatio

  13. Disease: H01282 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available uba H, Ravel C, Seeler J, Achermann JC, McElreavey K ... TITLE ... Human male infertility...y LJ, Yan W, Lamb DJ, Matzuk MM ... TITLE ... Non-invasive genetic diagnosis of male infertility

  14. Disease: H00031 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00031 Breast cancer Breast cancer is the leading cause of cancer death among women... ... Schmidt JW, Wollner D, Curcio J, Riedlinger J, Kim LS. ... TITLE ... Hormone replacement therapy in menopausal women

  15. Disease: H00030 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00030 Cervical cancer Cervical cancer is the second largest cause of cancer-related death in women...r WC, Kaufman R, Herbst AL, Hoover RN. ... TITLE ... Cancer risk in women prenatall

  16. Disease: H01635 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available iglyceride (TG), or both, is the most common form of dyslipidemia. Hyperlipidemia...rtriglyceridemia; Mixed dyslipidemia Dyslipidemia is a condition characterized by either an increase or decr... H01635 Hyperlipidemia, including: Hyperlipoproteinemia; Hypercholesterolemia; Hype

  17. Disease: H00214 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00214 Hypophosphatemic rickets, including: X-Linked dominant hypophosphatemia (XL...H); X-Linked recessive hypophosphatemia (XLRH); Autosomal dominant hypophosphatemic rickets (ADHR); Autosoma...l recessive hypophosphatemic rickets (ARHR); Hereditary hypophophatemic rickets with hypercalciuria (HHRH) Hypophosphataemic rickets..., also known as vitamin D resistant rickets, is a group o...ulting in hypophosphatemia and rickets associated with mineralization defect. Fibroblast growth factor-23 (F

  18. Civilsamfundets ABC: H for Handling

    DEFF Research Database (Denmark)

    Lund, Anker Brink; Meyer, Gitte

    2015-01-01

    Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til H for Handling.......Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til H for Handling....

  19. Disease: H00933 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00933 Hereditary pancreatitis; Hereditary chronic pancreatitis Hereditary pancreatitis... is a very rare form of chronic relapsing pancreatitis. ... Its inheritance mode is autosomal dominant wit...h an incomplete penetrance (80%). Patients had recurrent pancreatitis with impairment of endocrine and exocr...rely pancreatic cancer. The age of onset is early and differs from the cases of non-hereditary pancreatitis....e) ... AUTHORS ... Rebours V, Levy P, Ruszniewski P ... TITLE ... An overview of hereditary pancreatitis. ... JOURNA

  20. Disease: H00998 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00998 Alternating hemiplegia of childhood Alternating hemiplegia of childhood (AC...s. A characteristic feature of AHC is the disappearance of all abnormalities when the child...ic migraine (H00775) and alternating hemiplegia of childhood (AHC) share some cli...icardi J, Goutieres F ... TITLE ... Alternating hemiplegia of childhood. ... JOURNAL ... J Pediatr 122:673-9 (1993... ... A novel mutation in the ATP1A2 gene causes alternating hemiplegia of childhood. ... JOURNAL ... J Med Genet 4

  1. Programmable pH buffers

    Science.gov (United States)

    Gough, Dara Van; Huber, Dale L.; Bunker, Bruce C.; Roberts, Mark E.

    2017-01-24

    A programmable pH buffer comprises a copolymer that changes pK.sub.a at a lower critical solution temperature (LCST) in water. The copolymer comprises a thermally programmable polymer that undergoes a hydrophobic-to-hydrophilic phase change at the LCST and an electrolytic polymer that exhibits acid-base properties that are responsive to the phase change. The programmable pH buffer can be used to sequester CO.sub.2 into water.

  2. Zeolite encapsulation of H2

    International Nuclear Information System (INIS)

    Cooper, S.; Lakner, J.F.

    1982-08-01

    Experiments with H 2 have shown that it is possible to encapsulate gases in the structure of certain molecular sieves. This method may offer a better means of temporarily storing and disposing of tritium over some others presently in use. The method may also prove safer, and may enable isotope separation, and removal of 3 He. Initial experiments were performed with H 2 to screen potential candidates for use with tritium

  3. Disease: H00863 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00863 Spondylo-megaepiphyseal-metaphyseal dysplasia Spondylo-megaepiphyseal-metaphyseal dysplasia... is a rare skeletal dysplasia. Its features are disproportionate short stature. On radiograp...h, defective ossification of vertebral bodies, enlarged epiphyses, and metaphyseal dysplasia are noted. It i...s inherited as an autosomal recessive trait. Skeletal dysplasia NKX3-2 [HSA:579] ...[KO:K09995] ... The diseases similar to spondylo-megaepiphyseal-metaphyseal dysplasia include spondylometaphyseal dysplasia

  4. Individual Impact of Distinct Polysialic Acid Chain Lengths on the Cytotoxicity of Histone H1, H2A, H2B, H3 and H4

    Directory of Open Access Journals (Sweden)

    Kristina Zlatina

    2017-12-01

    Full Text Available Neutrophils are able to neutralize pathogens by phagocytosis, by the release of antimicrobial components, as well as by the formation of neutrophil extracellular traps (NETs. The latter possibility is a DNA-meshwork mainly consisting of highly concentrated extracellular histones, which are not only toxic for pathogens, but also for endogenous cells triggering several diseases. To reduce the negative outcomes initiated by extracellular histones, different approaches like antibodies against histones, proteases, and the polysaccharide polysialic acid (polySia were discussed. We examined whether each of the individual histones is a binding partner of polySia, and analyzed their respective cytotoxicity in the presence of this linear homopolymer. Interestingly, all of the histones (H1, H2A, H2B, H3, and H4 seem to interact with α2,8-linked sialic acids. However, we observed strong differences regarding the required chain length of polySia to bind histone H1, H2A, H2B, H3, and H4. Moreover, distinct degrees of polymerization were necessary to act as a cytoprotective agent in the presence of the individual histones. In sum, the outlined results described polySia-based strategies to bind and/or to reduce the cytotoxicity of individual histones using distinct polySia chain length settings.

  5. Biogeochemistry of dihydrogen (H2).

    Science.gov (United States)

    Hoehler, Tori M

    2005-01-01

    Hydrogen has had an important and evolving role in Earth's geo- and biogeochemistry, from prebiotic to modern times. On the earliest Earth, abiotic sources of H2 were likely stronger than in the present. Volcanic out-gassing and hydrothermal circulation probably occurred at several times the modern rate, due to presumably higher heat flux. The H2 component of volcanic emissions was likely buffered close to the modern value by an approximately constant mantle oxidation state since 3.9 billion years ago, and may have been higher before that, if the early mantle was more reducing. The predominantly ultramafic character of the early, undifferentiated crust could have led to increased serpentinization and release of H2 by hydrothermal circulation, as in modern ultramafic-hosted vents. At the same time, the reactive atmospheric sink for H2 was likely weaker. Collectively, these factors suggest that steady state levels of H2 in the prebiotic atmosphere were 3-4 orders of magnitude higher than at present, and possibly higher still during transient periods following the delivery of Fe and Ni by large impact events. These elevated levels had direct or indirect impacts on the redox state of the atmosphere, the radiation budget, the production of aerosol hazes, and the genesis of biochemical precursor compounds. The early abiotic cycling of H2 helped to establish the environmental and chemical context for the origins of life on Earth. The potential for H2 to serve as a source of energy and reducing power, and to afford a means of energy storage by the establishment of proton gradients, could have afforded it a highly utilitarian role in the earliest metabolic chemistry. Some origin of life theories suggest the involvement of H2 in the first energy-generating metabolism, and the widespread and deeply-branching nature of H2-utilization in the modern tree of life suggests that it was at least a very early biochemical innovation. The abiotic production of H2 via several mechanisms

  6. Laser spectroscopy of relativistic beams of H- and H

    International Nuclear Information System (INIS)

    Smith, W.W.; Tang, C.Y.; Harris, P.G.; Mohagheghi, A.H.; Bryant, H.C.; Reeder, R.A.; Toutounchi, H.; Sharifian, H.

    1989-01-01

    Laser spectroscopy on near-light velocity H- ions and H atoms has been carried out at the Los Alamos Meson Physics Facility using a variety of fixed frequency lasers intersecting accelerated beams at variable angles. Beam energies up to 800 MeV (v/c) = 0.84 make possible an unusually wide tuning range at modestly high resolution. A dedicated beam line, the High Resolution Atomic Beam (HIRAB), also makes possible Stark effect and field ionization studies in the multi-megavolt/cm range. Preliminary results on multiphoton detachment of fast H-ions using a pulsed CO 2 laser focussed to ∼10 11 W/cm 2 over a factor 10 photon energy range (CM frame) are presented in this paper

  7. Atmospheric photochemical loss of H and H2 from formaldehyde

    DEFF Research Database (Denmark)

    Simonsen, Jens Bæk; Rusteika, Nerijus; Johnson, Matthew Stanley

    2008-01-01

    We have performed ab initio calculations to examine the potential energy along the normal modes of ground-state HCHO and along the reaction coordinates for loss of H2 and atomic hydrogen, respectively. This exploration showed that there are no specific features that will lead to reaction on the e......We have performed ab initio calculations to examine the potential energy along the normal modes of ground-state HCHO and along the reaction coordinates for loss of H2 and atomic hydrogen, respectively. This exploration showed that there are no specific features that will lead to reaction...... on the excited-state surfaces for excitations that are relevant to the troposphere and stratosphere. The calculations did however lead to the localization of a conical intersection point through which a specific loss of H2 could take place. However, the conical intersection lies at 5.4 eV relative to the ground...

  8. Preparation of 2H- and 3H-labelled carvone

    International Nuclear Information System (INIS)

    Banthorpe, D.V.; Brown, G.D.

    1989-01-01

    (-)-Carvone labelled with 2 H or 3 H at C-10 was prepared by two methods. The first, involving a reversible ene reaction yielded 10-deuteriocarvone with some substitution at other reactive centres. An improvement to this route involved the decompositon of an organozinc reagent of 10-chloro-carvone which gave a better yield of product substituted only at C-10. As a preliminary to a possible radioimmunoassay with the above material, four derivatives of carvone linked to bovine serum albumin were prepared. (author)

  9. Syntheses of [5-2H]-uracil, [5-2H]-cytosine, [6-2H]-uracil and [6-2H]-cytosine

    International Nuclear Information System (INIS)

    Kiritani, Reiko; Asano, Takeyoshi; Fujita, Shin-ichi; Dohmaru, Takaaki; Kawanishi, Tetsuro

    1986-01-01

    Syntheses of [5- 2 H]-, [6- 2 H]-uracil and [5- 2 H]-, [6- 2 H]-cytosine were investigated. The catalytic reaction of uracil or cytosine with 2 H 2 gas in alkaline media gave rise to [6- 2 H]-compounds almost exclusively. On the other hand, the reaction of 5-bromouracil or 5-bromocytosine with 2 H 2 gas gave rise to a mixture of [5- 2 H]-, [6- 2 H]- and [5- 2 H, 6- 2 H]-compounds depending on the experimental conditions. By controlling the temperature, the pressure of 2 H 2 gas and the amount of catalyst, [5- 2 H]-uracil and [5- 2 H]-cytosine were obtained. The isotopic distribution in each product was measured by 1 H NMR spectroscopy combined with an HPLC method. (author)

  10. Preparation of deuteriated adipic [2H2]-, [2H4]-, [2H6]-, and [2H8]-acids by use of Kolbe electrolysis as a key reaction

    International Nuclear Information System (INIS)

    Tashiro, Masahi; Tsuzuki, Hirohisa; Mataka, Shuntaro; Goto, Hideyuki; Ogasahara, Shoji

    1990-01-01

    Using Kolbe electrolysis of methyl hydrogen [ 2 H 0 ]-, [ 2 H 2 ]-, and [ 2 H 4 ]-succinates as a key reaction, adipic [2,2- 2 H 2 ]-, [2,3- 2 H 2 ]-, [2,2,3,3- 2 H 4 ]-, [2,3,4,5- 2 H 4 ]-, [2,3,5,5- 2 H 4 ]-, [2,2,3,3,5,5- 2 H 6 ]-, and [2,2,3,3,4,4,5,5- 2 H 8 ]-acids were prepared in high deuterium contents. (author)

  11. Immune response to H pylori

    Science.gov (United States)

    Suarez, Giovanni; Reyes, Victor E; Beswick, Ellen J

    2006-01-01

    The gastric mucosa separates the underlying tissue from the vast array of antigens that traffic through the stomach lumen. While the extreme pH of this environment is essential in aiding the activation of enzymes and food digestion, it also renders the gastric epithelium free from bacterial colonization, with the exception of one important human pathogen, H pylori. This bacterium has developed mechanisms to survive the harsh environment of the stomach, actively move through the mucosal layer, attach to the epithelium, evade immune responses, and achieve persistent colonization. While a hallmark of this infection is a marked inflammatory response with the infiltration of various immune cells into the infected gastric mucosa, the host immune response is unable to clear the infection and may actually contribute to the associated pathogenesis. Here, we review the host responses involved during infection with H pylori and how they are influenced by this bacterium. PMID:17007009

  12. Disease: H01409 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01409 Methicillin-sensitive Staphylococcus aureus (MSSA) infection Staphylococcus... of the human population. Methicillin-resistant S. aureus (MRSA) is known to have evolved from methicillin-s...e mec (SCCmec) element which includes the mecA gene coding for resistance to the antibiotic methicillin. A h...ighly cytotoxic and clinically virulent methicillin-sensitive strain, S. aureus strain 6850 is a well-charac... ... Complete Genome Sequence of Staphylococcus aureus 6850, a Highly Cytotoxic and Clinically Virulent Methic

  13. H1 in RSA galaxies

    Science.gov (United States)

    Richter, OTTO-G.

    1993-01-01

    The original Revised Shapley-Ames (RSA) galaxy sample of almost 1300 galaxies has been augmented with further bright galaxies from the RSA appendix as well as newer galaxy catalogs. A complete and homogeneous, strictly magnitude-limited all-sky sample of 2345 galaxies brighter than 13.4 in apparent blue magnitude was formed. New 21 cm H1 line observations for more than 600 RSA galaxies have been combined with all previously available H1 data from the literature. This new extentise data act allows detailed tests of widely accepted 'standard' reduction and analysis techniques.

  14. Disease: H00146 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00146 Alpha-N-acetylgalactosaminidase deficiency, including: Schindler disease; K...ided into three types. Type 1 is Schindler disease, characterized by mental retardation, spasticity ,and myo...n alpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease). ... JOURNAL ... J Hum Genet 49:1-8 (20... ... TITLE ... The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler a...eland AM, de Jong JG, Wevers RA, Renier WO, Schindler D, Coll MJ, Chabas A, Sakuraba H, Suzuki Y, van Diggel

  15. Disease: H01239 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01239 Combined SAP deficiency; Prosaposin deficiency Combined SAP deficiency is a...aused by mutations in the PSAP gene leading to absence or non-functionality of the prosaposin protein. Mammalian prosapos...in encodes in tandem four small acidic activator proteins (saposins)...e PSAP [HSA:5660] [KO:K12382] ... Defects in PSAP saposin-B region are the cause of metachromatic leukodyst...rophy [DS:H00127]. Defects in PSAP saposin-C region are the cause of atypical Gau

  16. Disease: H00896 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00896 Lymphangioleiomyomatosis (LAM) Lymphangioleiomyomatosis (LAM) is a rare lun...led lymphatic cystic structures (lymphangioleiomyomas) in the axial lymphatics and of angiomyolipomas in the..., Moss J ... TITLE ... Prevalence of uterine leiomyomas in lymphangioleiomyomatosis. ... JOURNAL ... Fertil Steril...sotegui Barrera E, Mancheno Franch N, Vera-Sempere F, Padilla Alarcon J ... TITLE ... Lymphangioleiomyoma

  17. Disease: H00804 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00804 Multiple cutaneous and uterine leiomyomata Multiple cutaneous and uterine leiomyoma...patients with MCUL develop renal cancer and this condition is called hereditary leiomyoma... mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and...th a diffuse variant of cutaneous leiomyomatosis (Reed's syndrome). ... JOURNAL ... Dermatology 221:378-80 (2010) DOI:10.1159/000321336

  18. Disease: H00968 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00968 Raine syndrome; Lethal osteosclerotic bone dysplasia Raine syndrome or lethal osteosclerotic...utations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Rain...) DOI:10.1086/522240 ... PMID:1642277 (description) ... AUTHORS ... Kan AE, Kozlowski K ... TITLE ... New distinct lethal osteosclerotic

  19. Disease: H01399 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ng laboratory contamination, there are only two clinical reports of B. thuringiensis infection. Both the cas...onkukian (serotype H34) superinfection: case report and experimental evidence of pathogenicity in immunosuppressed mice. ... JOURNAL ... J Clin Microbiol 36:2138-9 (1998)

  20. Disease: H00907 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00907 Kleefstra syndrome; 9q Subtelomeric deletion syndrome Kleefstra syndrome, a...lso known as the 9q subtelomeric deletion syndrome is characterized by intellectual disability, childhood hy...potonia, and distinctive facial features. About 75% of Kleefstra syndrome is caused by microdeletion of 9q34

  1. Disease: H00803 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00803 Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance... (SESAME) ; SeSAME/EAST syndrome Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance...l deficit, and electrolyte imbalance. This disease links to autosomal recessive m

  2. Disease: H01718 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available of patients show resistance to IVIG therapy and present higher risk of coronary vasculitis. If there is no r... H01718 Kawasaki disease; Mucocutaneous lymph node syndrome Kawasaki disease (KD) is an acute systemic vascu...litis of childhood that does not have a known cause or aetiology. KD is a self-limi

  3. Disease: H00753 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Aydogdu O, Derbent M, Garcia-Minaur S, Reardon W, Gener B, Shalev S, Smith R, Wo... SB, Urquhart JE, Hilton E, McKenzie EA, Kammerer RA, Lewis M, Kerr B, Stuart H, Donnai D, Long DA, Burgu B,

  4. Disease: H00925 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available the HSD17B10 gene. See also H00658. ICD-10: E71.3 MeSH: C536080 OMIM: 300438 PMID:16148061 ... AUTHORS ... Perez-Cerda C, Garcia...-Villoria J, Ofman R, Sala PR, Merinero B, Ramos J, Garcia-Silva

  5. Disease: H01447 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01447 Body Dysmorphic Disorder Body dysmorphic disorder (BDD) is a psychiatric di... of Mental Disorders (DSM-5), body dysmorphic disorder (BDD) has been subsumed into the obsessive-compulsive...ompulsive disorder and body dysmorphic disorder: prevalence, explanatory theories, and clinical characteriza

  6. Disease: H01514 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01514 Landau-Kleffner syndrome; Acquired epileptic aphasia Landau-Kleffner syndro...y, however, only 70% have clinical seizures. The main symptoms are acute or subacute aphasia...S ... Bhardwaj P, Sharma VK, Sharma R, Gautam P ... TITLE ... Acquired epileptic aphasia

  7. Disease: H01721 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01721 Anti-glomerular basement membrane (GBM) disease; Goodpasture syndrome Goodp...asture syndrome (GS), or anti-glomerular basement membrane (anti-GBM) disease, is a rare and organ-specific ...n of the alpha 3 chain of type IV collagen [alpha3(IV)NC1], found in the glomerular and alveolar basement me

  8. Peter H. Schlechtriem / Ingeborg Schwenzer

    Index Scriptorium Estoniae

    Schwenzer, Ingeborg

    2007-01-01

    Järelehüüe Saksa tsiviilõiguse arendajale, mitmete Euroopa ja Ameerika Ühendriikide ülikoolide külalisõppejõule, Tartu Ülikooli audoktorile, professor Peter H. Schlechtriemile (02. 03. 1933-23. 04. 2007)

  9. Disease: H01143 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01143 Vitamin D-dependent rickets Rickets is the failure of growing bone to miner...ldup of unossified cartilage. Vitamin D-dependent rickets type I results from abnormalities in the gene codi...by hypocalcemia, secondary hyperparathyroidism and early onset severe rickets. Musculoskeletal disease; Inhe

  10. Disease: H00347 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00347 Chlamydia infection, including the following disease: Chlamydial urethritis... lead to non-gonococcal urethritis and post-gonococcal urethritis in men. Urethri...ally transmissible diseases in the world. Most of these infections are asymptomatic but, if not treated, can

  11. Disease: H00252 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00252 Congenital nephrogenic diabetes insipidus (NDI) Nephrogenic diabetes insipi...HORS ... Linshaw MA ... TITLE ... Back to basics: congenital nephrogenic diabetes insipidus. ... JOURNAL ... Pediatr...lecular and cellular defects in nephrogenic diabetes insipidus. ... JOURNAL ... Pediatr Nephrol 16:1146-52 (2001) DOI:10.1007/s004670100051

  12. Disease: H01228 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN); Type ...A insulin resistance Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) is an unusual cause of diabetes... (description, gene) ... TITLE ... Diagnosis and classification of diabetes mellitu

  13. Disease: H01675 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available (CSF) flow dynamics related to hindbrain disorders, e.g. Chiari malformation, Dandy-Walker...ormation, and H01675 Dandy-Walker syndrome. ICD-10: G95.0 Q06.4 MeSH: D013595 OMIM: 186700 PMID:25236931 ... A

  14. Disease: H00120 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00120 Muscular dystrophy-dystroglycanopathy type A, including: Walker-Warburg syn...ycanopathy patients is extremely variable. At the most severe end of the clinical spectrum are Walker-Warbur...TITLE ... POMT2 mutations cause alpha-dystroglycan hypoglycosylation and Walker-Warburg syndrome. ... JOURNAL

  15. Disease: H01678 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01678 Dandy-Walker syndrome Dandy-Walker syndrome (DWS) is a congenital brain mal...erozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation. ... JOURNAL ... Nat Genet 36:1053-5 (2004) DOI:10.1038/ng1420 ...

  16. Disease: H00071 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00071 Hereditary fructose intolerance; Fructosemia Hereditary fructose intolerance... MeSH: D005633 OMIM: 229600 PMID:16086449 ... AUTHORS ... Wong D ... TITLE ... Hereditary fructose intolerance. ... JOURNAL ... Mol Genet Metab 85:165-7 (2005) DOI:10.1016/j.ymgme.2005.05.001 ...

  17. Disease: H01828 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01828 Opsismodysplasia Opsismodysplasia (OPS) is a rare, autosomal-recessive skel...THORS ... Fradet A, Fitzgerald J ... TITLE ... INPPL1 gene mutations in opsismodysplasia. ... JOURNAL ... J Hum Gene...ate phosphatase-like 1 cause opsismodysplasia. ... JOURNAL ... Am J Hum Genet 92:137-43 (2013) DOI:10.1016/j.ajhg.2012.11.011

  18. Disease: H01822 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01822 Epilepsy with myoclonic absence Epilepsy with myoclonic absences (EMA) is c... the long-term prognosis is poor. Nervous system disease; Epilepsy ... Valproate...sies. ICD-10: G40.3 MeSH: D004831 PMID:15737698 ... AUTHORS ... Bureau M, Tassinari CA ... TITLE ... Epilepsy with

  19. Disease: H01445 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01445 Acne vulgaris Acne is a chronic inflammatory disease of the pilosebaceous u...ms HC, Dellavalle RP, Garner S ... TITLE ... Acne vulgaris. ... JOURNAL ... Lancet 379:361-72 (2012) DOI:10.1016/S0140-6736(11)60321-8 ...

  20. Disease: H00865 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00865 Lethal congenital contractural syndrome (LCCS) Lethal congenital contractur...al syndrome (LCCS) is a heterogeneous group of disorders characterized by congenital nonprogressive joint contract...rk OS ... TITLE ... Lethal contractural syndrome type 3 (LCCS3) is caused by a mutation in PIP5K1C, which enco

  1. Disease: H01906 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01906 Poikiloderma, hereditary fibrosing, with tendon contractures, myopathy, and... pulmonary fibrosis Poikiloderma, hereditary fibrosing, with tendon contractures, myopathy, and pulmonary fi...ies especially on the face and sun-exposed areas. Scalp hair, eyelashes, and eyebrows are typically sparse. Tendon contract

  2. Disease: H00660 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00660 Congenital contractural arachnodactyly (CCA); Beals syndrome Congenital contract...-like appearance and arachnodactyly. Most affected individuals have 'crumpled' ears, contractures of major j...z DM ... TITLE ... Fibrillin-2 (FBN2) mutations result in the Marfan-like disorder, congenital contractural arachnodactyly. ... JOURNAL ... Nat Genet 11:456-8 (1995) DOI:10.1038/ng1295-456 ...

  3. Disease: H01269 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01269 Congenital hyperthyroidism, including: Familial gestational hyperthyroidism... (HTFG); Hyperthyroidism non-autoimmune (HTNA) Congenital hyperthyroidism is a rare clinical condition, and ...cular cause of congenital nonautoimmune hyperthyroidism. TSHR gene mutations also causes the familial gestational hyperthyroidism...cchera M ... TITLE ... Sporadic congenital nonautoimmune hyperthyroidism caused by P639S mutation in thyrotrop

  4. Disease: H01017 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01017 Choanal atresia and lymphedema Choanal atresia and lymphoedema is a rare co...orderon ML, Weiss MH ... TITLE ... Choanal atresia and lymphedema. ... JOURNAL ... Ann Otol Rhinol Laryngol 100:661-4 (1991) DOI:10.1177/000348949110000812 ...

  5. Disease: H00718 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ers. Developmental disorder NSD1 [HSA:64324] [KO:K15588] ... Beckwith-Wiedemann syndrome [DS:H00713] is a d..., Lyonnet S, Le Merrer M, Munnich A, Gicquel C, Cormier-Daire V, Colleaux L ... TITLE ... Paradoxical NSD1 mutations in Beckwith-Wiedem

  6. Disease: H01876 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01876 Microcephaly with or without chorioretinopathy, lymphedema, or mental retar...dation (MCLMR); Microcephaly, lymphedema, chorioretinal dysplasia (MLCRD) syndrome; Chorioretinal dysplasia,... microcephaly, and mental retardation (CDMMR) syndrome Microcephaly with or without chorioretinopathy, lymphoedema...ondition characterised by variable expression of microcephaly, eye problems including chorioretinopathy, congenital lymphoedema...s divided into two distinct entities: microcephaly, lymphedema, chorioretinal dys

  7. Disease: H01799 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01799 Vibratory urticaria; Vibratory angioedema Vibratory urticaria is a rare typ...e of physical skin reactivity characterized by the occurrence of local erythematous, edematous, cutaneous an...enship ML, Pruzansky JJ ... TITLE ... Vibratory angioedema: a hereditary type of ph

  8. Disease: H00768 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available us disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders. ... JOURNAL ... Hum M... H00768 Nonsyndromic autosomal recessive mental retardation (NS-ARMR) Mental retardation (MR) is a neurodeve...lopmental disorder characterized by low intelligence quotient (IQ) and deficits in

  9. Disease: H01499 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01499 Sporotrichosis Sporotrichosis is an endemic mycosis in tropical and subtrop...rotrichosis. ... JOURNAL ... Clin Dermatol 30:437-43 (2012) DOI:10.1016/j.clindermatol.2011.09.017 ...DOI:10.1093/mmy/myu062 ... PMID:22682194 (description) ... AUTHORS ... Vasquez-del-Mercado E, Arenas R, Padilla-Desgarenes C ... TITLE ... Spo

  10. Disease: H01500 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available odies (anti-nuclear, anti-dsDNA, anti-C1q) Cyclophosphamide [DG:DG00675] Prednisone [DG:DG00094] Tacrolimus [DG:DG00439] Hydroxychlor...oquine [DG:DG01015] See also H00080 Systemic lupus erythematosus. Lupus nephritis i

  11. Disease: H01443 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available isms are also occasional pathogens in healthy children and adults, causing infections such as subacute endoc...h viridans group streptococci in children with cancer. ... JOURNAL ... Pediatr Blood Cancer 49:774-80 (2007) DOI:10.1002/pbc.21250

  12. Disease: H01133 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01133 Reynolds syndrome Reynolds syndrome is a rare disease associating primary b...the white blood cells, suggesting that nuclear signalling defects could be a cause in Reynolds syndrome. Ski... ... ICD-10: K74.5 L94.0 OMIM: 613471 PMID:20800400 (description) ... AUTHORS ... Cabane J ... TITLE ... Is Reynolds

  13. Disease: H00155 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00155 Familial hypercholesterolemia; Autosomal dominant hypercholesterolaemia Fam...n receptor. Other forms of this disorder include hypercholesterolemia caused by mutation of APOB or PCSK9 ge...amilial autosomal recessive hypercholesterolemia. ICD-10: E78.0 MeSH: D006937 OMI

  14. Disease: H00378 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00378 Lyssavirus infection; Rabies-related virus infection Lyssaviruses are a gro...up of viruses that includes rabies virus and other rabies-related bat lyssaviruses. Rabies-related lyssaviru...23] European bat lyssavirus 1 [GN:T40024] European bat lyssavirus 2 [GN:T40025] ... Rabies vaccine [DR:D06504] Rabies

  15. Disease: H01422 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01422 Carbapenem-resistant Enterobacteriaceae (CRE) infection Enterobacteriaceae ... Carbapenemase-producing Enterobacteriaceae: overview of a major public health ch...an Duin D ... TITLE ... Carbapenem-resistant Enterobacteriaceae: a menace to our mo...s. Carbapenem-resistant Enterobacteriaceae (CRE) have been increasingly reported worldwide. Bacterial acquis...erobacteriaceae: clinical perspectives on detection, tre

  16. Disease: H00696 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00696 Haim-Munk syndrome; Prepubertal periodontitis (PPP) Haim-Munk syndrome is a... rare autosomal recessive disorder of keratinization characterized by palmoplantar hyperkeratosis and marked periodontitis... acroosteolysis. Prepubertal periodontitis (PPP) is a rare and rapidly progressiv

  17. Disease: H00826 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available of the female patients have premature ovarian failure (POF) and this condition is classified as BPES type I... disorder FOXL2 [HSA:668] [KO:K09405] ... Premature ovarian failure is described in H00627. ICD-10: Q10.3 M

  18. Disease: H00862 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00862 Tourette syndrome Tourette's syndrome (TS) is a developmental neuropsychiat...State MW ... TITLE ... L-histidine decarboxylase and Tourette's syndrome. ... JOURNAL ... N Engl J Med 362:1901-8 ...(2010) DOI:10.1056/NEJMoa0907006 ... PMID:21277193 ... AUTHORS ... State MW ... TITLE ... The genetics of Tourette di

  19. Disease: H01705 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01705 Bilateral sudden sensorineural hearing loss Bilateral sudden sensorineural ...hearing loss (SNHL) represents a rare disease entity, constituting less than 5 % of all sudden SNHL cases. U...nlike unilateral disease, bilateral sudden SNHL appears to be mostly related to serious systemic pathology, ...543 603629 601072 600965 PMID:24331736 ... AUTHORS ... Sara SA, Teh BM, Friedland P ... TITLE ... Bilateral sud

  20. Disease: H01967 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ... Anauxetic dysplasia, a spondylometaepiphyseal dysplasia with extreme dwarfism. ... H01967 Anauxetic dysplasia Anauxetic dysplasia (AD) is a spondylometaepiphyseal dysplasia with extreme dwar...fism. Mutations in the RMRP gene that codes for an RNA subunit of the RNAse MRP com

  1. Disease: H01186 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available a disorder associated with an inherited selenocysteine (Sec) incorporation defect, caused by mutations in SECI...eiodinase type 2 (DIO2) enzymatic activity not linked to the DIO2 locus. Inherited metabolic disease SECISBP...C, Boran G, Schomburg L, Weiss RE, Refetoff S ... TITLE ... Mutations in SECISBP2 result in abnormal thyroid h

  2. Disease: H01109 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01109 Chronic mucocutaneous candidiasis (CMC); Familial candidiasis (CANDF) Chronic mucocutaneous candidia...mpair IL-17 immunity and underlie chronic mucocutaneous candidiasis. ... JOURNAL ... J Exp Med 208:1635-48 (2011) DOI:10.1084/jem.20110958 ...sis (CMC) is manifested as a primary immunodeficiency characterized by persistent o

  3. Disease: H00612 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00612 Primary open angle glaucoma Primary open angle glaucoma (POAG) is the most prevalent form of glaucom...ng K, Anholt RR ... TITLE ... Genes of the unfolded protein response pathway harbor risk alleles for primary open angle glaucoma...UTHORS ... Khan AO ... TITLE ... Genetics of primary glaucoma. ... JOURNAL ... Curr Opin

  4. Disease: H01473 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01473 Erythema nodosum leprosum (ENL) Reactional states of leprosy are expression...rsal reaction) and type 2 (Jopling's type II reaction). Erythema Nodosum Leprosum (ENL), the main symptom of a type-2 reaction in lep...rosy, is caused by a humoral immune response to Mycobact

  5. Disease: H01830 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01830 Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM) Spondyl...ometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM) is a rare, autosomal-recessive lethal skeletal ...) DOI:10.1371/journal.pgen.1004311 ... PMID:18925669 (description) ... AUTHORS ... Megarbane A, Dagher R, Melki I ...

  6. Et håndtryk

    DEFF Research Database (Denmark)

    2010-01-01

    Hør Karen Westphal Eriksen fortælle om udvalgte værker og temaer fra udstillingen "Et håndtryk". Udstillingen omhandler dansk-fransk avantgardekunst og er et samarbejde mellem Fyns Kunstmuseum og Statens Museum for Kunst. Udstillingen kan ses på Fyns Kunstmuseum frem til februar 2011...

  7. Disease: H00312 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00312 Tularemia Tularemia is a rare zoonotic infection caused by the bacterium Fr...edlinePlus: 000856 PMID:19713053 (description, env_factor) ... AUTHORS ... Foley JE, Nieto NC ... TITLE ... Tula...remia. ... JOURNAL ... Vet Microbiol 140:332-8 (2010) DOI:10.1016/j.vetmic.2009.07.017

  8. pH in Action

    NARCIS (Netherlands)

    Tijskens, L.M.M.; Biekman, E.S.A.

    2001-01-01

    Based on fundamental chemical relations, well-established in chemical engineering and chemical technology over almost a century, the effects of pH in food and agricultural products will be deduced for different situations and processes. Based on simple equilibria and dissociation of water, salts,

  9. The RESCueH Programme

    DEFF Research Database (Denmark)

    Søgaard Nielsen, Anette; Nielsen, Bent; Andersen, Kjeld

    2016-01-01

    Excessive alcohol consumption is one of the most important lifestyle factors affecting the disease burden in the Western world. The results of treatment in daily practice are modest at best. The aim of the RESCueH programme is to develop and evaluate methods, which are as practice-near as possible...

  10. Disease: H00078 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 8-007-0102-4 ... PMID:17596717 ... AUTHORS ... van der Zee J, Gijselinck I, Pirici D, Kumar-Singh S, Cruts M, Van B...hetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, Akiyama H, Babor

  11. Disease: H00691 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00691 Bullous congenital ichthyosiform erythroderma (BCIE); Epidermolytic hyperkeratosis...LE ... Histopathologic characterization of epidermolytic hyperkeratosis: a systematic review of histology fr...AUTHORS ... Lacz NL, Schwartz RA, Kihiczak G ... TITLE ... Epidermolytic hyperkeratosis: a keratin 1 or 10 mutat

  12. Disease: H00755 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00755 Acrokeratosis verruciformis Acrokeratosis verruciformis is a rare autosomal...S, Dode L, Leslie N, Sakuntabhai A, MacSween R, Saihan E, Hovnanian A ... TITLE ... Acrokeratosis verruciformi...16150218 (description) ... AUTHORS ... Rallis E, Economidi A, Papadakis P, Verros C ... TITLE ... Acrokeratosis ve

  13. Disease: H00871 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00871 Leukoencephalopathy with brain stem and spinal cord involvement and lactate... ... van Berge L, Dooves S, van Berkel CG, Polder E, van der Knaap MS, Scheper GC ... TITLE ... Leukoencephalopathy... elevation (LBSL) Leukoencephalopathy with brain stem and spinal cord involvement and brain lactate elevatio

  14. Disease: H01506 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01506 Hepatic encephalopathy; Hepatic coma Hepatic encephalopathy (HE) is a brain...of current therapies for hepatic encephalopathy in liver cirrhosis. ... JOURNAL ... World J Gastroenterol 21:118... ... Wakim-Fleming J ... TITLE ... Hepatic encephalopathy: suspect it early in patients with cirrhosis. ... JOURNAL ... Cleve Clin J Med 78:597-605 (2011) DOI:10.3949/ccjm.78a10117

  15. Disease: H00878 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00878 Cystic leukoencephalopathy without megalencephaly Cystic leukoencephalopathy...iduals are asymptomatic at birth and show a static encephalopathy with normo- or microcephaly and psychomoto...tner J ... TITLE ... RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection. ... JOURNAL ... Nat Genet 41:773-5 (2009) DOI:10.1038/ng.398

  16. Disease: H00875 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00875 Megalencephalic leukoencephalopathy with subcortical cysts (MLC) Megalencephaiic leukoencephalopathy...tion, gene) ... AUTHORS ... Singhal BS, Gorospe JR, Naidu S ... TITLE ... Megalencephalic leukoencephalopathy with...naap MS ... TITLE ... Mutant GlialCAM causes megalencephalic leukoencephalopathy with subcortical cysts, benig

  17. Disease: H01211 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01211 MECP2-related severe neonatal encephalopathy MECP2-related severe neonatal encephalopathy... is a rare disorder of males characterized by a static encephalopathy, severe developmental de...BC ... TITLE ... MECP2 mutation in a boy with severe neonatal encephalopathy: clinical, neuropathological and

  18. Disease: H01204 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01204 Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CA...MRQ) Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ) is autosomal recessive,... Mutations in VLDLR as a cause for autosomal recessive cerebellar ataxia with mental retardation (dysequilibrium

  19. Disease: H01842 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01842 Bickerstaff brainstem encephalitis Bickerstaff's brainstem encephalitis (BB...379047 ... AUTHORS ... Rho YI ... TITLE ... Overlapping Guillain-Barre syndrome and Bickerstaff's brainstem enceph...ya K, Hamasaki Y, Yuki N ... TITLE ... Bickerstaff's brainstem encephalitis associated with IgM antibodies to

  20. Disease: H01327 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01327 Herpangina Herpangina is a vesicular exanthem of the fauces and soft palate...ot-mouth disease and herpangina caused by enterovirus 71 in Taiwan, 1998-2005. ... JOURNAL ... Pediatrics 120:e244-52 (2007) DOI:10.1542/peds.2006-3331

  1. Disease: H00495 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00495 Eiken dysplasia Eiken dysplasia is an extremely rare form of epiphyseal dysplasia.... It is caused by a homozygous nonsense mutation in the PTHR1 gene. Skeletal dysplasia PTHR1 [HSA:5745...D, Lemainque A, Julier C ... TITLE ... Recessive mutations in PTHR1 cause contrasting skeletal dysplasia

  2. Disease: H01112 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01112 Polyhydramnios, megalencephaly, and symptomatic epilepsy; PMSE syndrome Pol...yhydramnios, megalencephaly, symptomatic epilepsy (PMSE) is a severe human developmental and epileptic syndr...al retardation, gross movement disorders, and childhood mortality. Severe intractable epilepsy and megalence

  3. Disease: H00996 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00996 Amish infantile epilepsy syndrome Amish infantile epilepsy syndrome is an a...utosomal recessive, infantile-onset symptomatic epilepsy associated with developmental stagnation and blindn...TD, Platt FM, Crosby AH ... TITLE ... Infantile-onset symptomatic epilepsy syndrome

  4. Disease: H00807 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE); Nocturnal frontal lobe epilepsy... (NFLE) Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is characterized by noc...M, Verrotti A, Chiarelli F ... TITLE ... Recent advances on autosomal dominant nocturnal frontal lobe epilepsy

  5. Siempelkamp Nukleartechnik GmbH

    International Nuclear Information System (INIS)

    2011-01-01

    Siempelkamp Nukleartechnik GmbH, which is headquartered in Krefeld (Germany), is at the forefront of the nuclear technology companies in the Siempelkamp group. With over 2,700 employees, Siempelkamp is a traditional family enterprise, and its individual divisions represent it as an internationally active industrial supplier in the markets of machinery and plants, nuclear technology, and foundry technology. (orig.)

  6. Disease: H00012 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00012 Polycythemia vera Polycythemia vera (PV) is a clonal myeloproliferative dis...[DR:D00341] ICD-O: 9950/3, Tumor type: Polycythemia vera ICD-10: D45 MeSH: D01108...7 PMID:16879013 (gene, tumor type) ... AUTHORS ... Cao M, Olsen RJ, Zu Y. ... TITLE ... Polycythemia vera: new cli

  7. 4-H Club Goat Guide.

    Science.gov (United States)

    Brown, R. Kipp

    This guide provides information for 4-H Club members who have decided on a club goat project. Topics include general information in the following areas: show rules; facilities and equipment (barns/sheds, fences, feeders, water containers, and equipment); selection (structural correctness, muscle, volume and capacity, style and balance, and growth…

  8. H1 antihistamines and driving

    OpenAIRE

    Florin-Dan, Popescu

    2008-01-01

    Driving performances depend on cognitive, psychomotor and perception functions. The CNS adverse effects of some H1 antihistamines can alter the patient ability to drive. Data from studies using standardized objective cognitive and psychomotor tests (Choice Reaction Time, Critical Flicker Fusion, Digital Symbol Substitution Test), functional brain imaging (Positron Emission Tomography, functional Magnetic Resonance Imaging), neurophysiological studies (Multiple Sleep Latency Test, auditory and...

  9. Disease: H00891 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available wlers ZM, Lightowlers RN, Taylor RW, Horvath R ... TITLE ... Nuclear factors involv... RG, Ferrero I, Haack TB, Taylor RW, Prokisch H, Minczuk M ... TITLE ... TRMT5 Mutations Cause a Defect in Pos..., Filipovska A, Munnich A, Chinnery PF, McFarland R, Rotig A, Taylor RW ... TITLE ...

  10. Disease: H00271 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Hayward BE, Carr IM, Springell K, Woods CG, Ahmed M, Hattingh L, Corry P, Pilz DT, Stoodley N, Crow Y, Taylor...eays DA, Quaghebeur G, Cox H, Cox P, Balla T, Taylor JC, Kini U ... TITLE ... Germline recessive mutations in

  11. Disease: H00609 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00609 46,XY disorders of sex development (Other), including: Persistent Mullerian...E ... AMH and AMH receptor defects in persistent Mullerian duct syndrome. ... JOURNAL ... Hum Reprod Update 11:3... duct syndrome; Hypospadias; Cryptorchidism 46,XY disorders of sex development (46,XY DSD) with other variou...s causes includes persistent Mullerian duct syndrome, hypospadias, and cryptorchidism. During embryogenesis,

  12. Disease: H00508 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00508 Blomstrand syndrome; Blomstrand chondrodysplasia Blomstrand syndrome is a l...rd E, Cortes D, Lemainque A, Julier C ... TITLE ... Recessive mutations in PTHR1 cause contrasting skeletal dy...splasias in Eiken and Blomstrand syndromes. ... JOURNAL ... Hum Mol Genet 14:1-5 (2005) DOI:10.1093/hmg/ddi001

  13. Temperature dependence of third order ion molecule reactions. The reaction H+3 + 2H2 = H+5 + H2

    International Nuclear Information System (INIS)

    Hiraoka, K.; Kebarle, P.

    1975-01-01

    The rate constants k 1 for Reaction (1): H + 3 +2H 2 = H + 5 +H 2 were measured in the temperature range 100--300 degreeK. The temperature dependence of k 1 has the form k 1 proportionalT - /subn/, where n=2.3. Pierce and Porter have reported a much stronger negative temperature dependence with n=4.6. The difference arises from a determination of k 1 at 300 degreeK obtained by Arifov and used by Porter. The present k 1 (300 degreeK) =9times10 -30 (cm 6 molecules -2 center-dotsec -1 ). This is more than an order of magnitude larger than the Arifov value. The temperature dependence of third body dependent association reactions like (1) is examined on the basis of the energy transfer theory and the recently proposed trimolecular complex transition state theory by Meot-Ner, Solomon, Field, and Gershinowitz. The temperature dependence of the rate constant for the reverse reaction (-1) is obtained from k 1 and the previously determined temperature dependence of the equilibria (1). k/sub -//sub 1/ gives a good straight line Arrhenius plot leading to k/sub -//sub 1/ =8.7times10 -6 exp(-8.4/RT) cm 3 molecules -1 center-dotsec -1 . The activation energy is in kcal/mole. The preexponential factor is much larger than the rate constant for Langevin collisions. This is typical for pyrolysis of ions involving second order activation

  14. Disease: H01115 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01115 Polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract (PHARC) Polyneuropathy, hea...osomal-recessive, neurodegenerative disease marked by early-onset cataract and hearing loss, retinitis pigme...ring loss, ataxia, retinitis pigmentosa, and cataract (PHARC) is a progressive, aut

  15. Disease: H01286 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01286 Microtia hearing impairment and cleft palate (MHICP) Microtia is a congenit...al anomaly of the ear characterized by a small abnormally shaped outer ear. It is often associated with hearing...HOXA2 homeobox gene causes microtia, severe hearing impairment, and partial cleft palate. Developmental diso

  16. Disease: H01389 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01389 Alpers syndrome; Alpers-Huttenlocher syndrome; Diffuse cerebral sclerosis of Schild...er; Hepatocerebral degeneration of childhood; Mitochondrial DNA depletion syndrome 4A Alpers syndrom... polymerase gamma. Alpers syndrome affects children and young adults and is chara

  17. Disease: H01767 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available erally, the prognosis of Henoch-Schonlein purpura [DS:H01584] in children is favorable, but there are severe...JC, Coppo R ... TITLE ... Henoch-Schonlein purpura nephritis in children. ... JOURNAL ... Nat Rev Nephrol 10:563-73 (2014) DOI:10.1038/nrneph.2014.126

  18. Disease: H01132 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01132 Aplastic anemia (AA) Aplastic anemia (AA) is a rare disease in which the re...duction of the circulating blood cells results from damage to the stem cell pool in bone marrow. Most cases of acquired aplastic anem...ia are the consequence of an immune-mediated destruction of hematopoiesis. Autoreac

  19. Disease: H01278 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01278 Iron-refractory iron deficiency anemia (IRIDA) Iron-refractory iron deficiency anemia...LE ... Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). ... JOURNAL ... Nat Genet 40:569-71 (2008) DOI:10.1038/ng.130 ...

  20. Disease: H01642 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01642 Renal anemia Renal anemia is one of the most frequent complications of chro...sated for by tachycardia and cardiac hypertrophy, but eventually leads to the development of cardiovascular disease. Renal anemia... human erythropoietin has revolutionized the management of renal anemia, and erythropoiesis-stimulating agen

  1. Disease: H00917 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00917 Congenital dyserythropoietic anemias (CDAs) Congenital dyserythropoietic anemia...ion, gene) ... AUTHORS ... Iolascon A, Russo R, Delaunay J ... TITLE ... Congenital dyserythropoietic anemias. ... J...AUTHORS ... Kamiya T, Manabe A ... TITLE ... Congenital dyserythropoietic anemia. ... JOURNAL ... Int J Hematol 92:432-8 (2010) DOI:10.1007/s12185-010-0667-9 ...

  2. Disease: H01585 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01585 Autoimmune hemolytic anemia (AIHA) Autoimmune hemolytic anemia (AIHA) is a ...cating an underlying disease. AIHA may develop gradually, or have a fulminant onset with life-threatening anemia.... The diagnosis is usually simple, based on the presence of hemolytic anemia

  3. Disease: H01111 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available . 11beta-HSD1 is a dimeric enzyme that catalyzes the reduction of cortisone to cortisol within the endoplasm...ed metabolic disease; Endocrine disease H6PD [HSA:9563] [KO:K13937] HSD11B1 [HSA:3290] [KO:K15680] ... Extremely low ratio of cortisol

  4. Disease: H00334 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00334 Bacterial endocarditis; Infective endocarditis Infective endocarditis is a ...tendineae, or on the mural endocardium. Staphylococci and streptococci account for 80% of cases of infective endocarditis... AUTHORS ... Hoen B, Duval X ... TITLE ... Clinical practice. Infective endocarditis. ... JOURNAL ... N Engl J Med 368:1425-33 (2013) DOI:10.1056/NEJMcp1206782 ...

  5. Disease: H00913 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00913 Choreoathetosis, hypothyroidism, and neonatal respiratory distress Choreoathetosis, hypothyroidism..., and neonatal respiratory distress is a syndrome of congenital hypothyroidism associ... Autosomal dominant transmission of congenital hypothyroidism, neonatal respiratory distress, and ataxia cau... mutation in a family with hypothyroidism and benign hereditary chorea. ... JOURNAL ... Thyroid 18:1005-9 (2008) DOI:10.1089/thy.2008.0085

  6. Disease: H01932 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01932 Ablepharon-macrostomia syndrome Ablepharon-macrostomia syndrome (AMS) is a ...rare autosomal dominant condition characterized by absent eyelids, absent eyebrows and eyelashes, macrostomia...: 200110 PMID:15103726 (gene) ... AUTHORS ... Brancati F, Mingarelli R, Sarkozy A, Dallapiccola B ... TITLE ... Ablepharon-macrostomia

  7. Disease: H01890 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01890 Pattern dystrophies of the retinal pigment epithelium; Patterned macular dystrophy; Butterfly...:5442145 ... AUTHORS ... Deutman AF, van Blommestein JD, Henkes HE, Waardenburg PJ, Solleveld-van Driest E ... TITLE ... Butterfly...5 ... PMID:8485574 (gene) ... AUTHORS ... Nichols BE, Sheffield VC, Vandenburgh K, Drack AV, Kimura AE, Stone EM ... TITLE ... Butterfly

  8. Disease: H01033 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s (CF) that is characterized by progressive lung disease, pancreatic dysfunction, elevated sweat electrolytes, and male infertility... polymorphisms in male infertility. ... JOURNAL ... Int J Androl 27:251-6 (2004) DOI:10.1111/j.1365-2605.2004.00...ription , gene) ... AUTHORS ... Cuppens H, Cassiman JJ ... TITLE ... CFTR mutations and

  9. Neuronal pH regulation

    DEFF Research Database (Denmark)

    Vorstrup, S; Jensen, K E; Thomsen, C

    1989-01-01

    The intracellular pH in the brain was studied in six healthy volunteers before and immediately after the administration of 2 g of acetazolamide. Phosphorus-31 nuclear magnetic resonance spectroscopy by a 1.5 tesla whole-body scanner was used. The chemical shift between the inorganic phosphate...

  10. Disease: H00890 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available K, Kitaoka E, Sawada T, Nishiyama Y, Udagawa Y, Kurahashi H ... TITLE ... Mutations of the SYCP3 gene in wom...en with recurrent pregnancy loss. ... JOURNAL ... Am J Hum Genet 84:14-20 (2009) DOI:10.1016/j.ajhg.2008.12.002

  11. Disease: H01593 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available h age. It has been estimated that approximately 50% of all women will have osteop... calcitonin receptor gene are associated with bone mineral density in postmenopausal Italian women. ... JOURNA...rming growth factor-beta-1 gene polymorphism in Chinese men and women. ... JOURNAL ... J Bone Miner Metab 22:148

  12. Disease: H00344 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00344 Leprosy; Hansen disease Leprosy, caused by Mycobacterium leprae, is still o...LC, Lockwood DNj ... TITLE ... Leprosy now: epidemiology, progress, challenges, and research gaps. ... JOURNAL ... ... ... Cardoso CC, Pereira AC, de Sales Marques C, Moraes MO ... TITLE ... Leprosy susc

  13. Structure of LaH(PO3H)2.3H2O

    International Nuclear Information System (INIS)

    Loukili, M.; Durand, J.; Larbot, A.; Cot, L.; Rafiq, M.

    1991-01-01

    Lanthanum hydrogen bis(hydrogenphosphite) trihydrate, LaH(Po 3 H) 2 .3H 2 O, M r =353.8, monoclinic, P2 1 /c, a=9.687 (3), b=7.138 (2), c=13.518 A, β=104.48 (3) deg, V=905.0 (5) A 3 , Z=4, D m =2.56 (2), D x =2.598 Mg m -3 , λ(MoKα)=0.71073 A, μ(MoKα)=5.103 mm -1 , F(000)=672, T=300 K, R=0.032 for 1018 independent observed reflections. The structure contains two phosphite anions connected by a hydrogen bond. The La 3+ cation is eight coordinated by seven O atoms from phosphite anions and one O atom of a water molecule. (orig.)

  14. Teledyne H1RG, H2RG, and H4RG Noise Generator

    Science.gov (United States)

    Rauscher, Bernard J.

    2015-01-01

    This paper describes the near-infrared detector system noise generator (NG) that we wrote for the James Webb Space Telescope (JWST) Near Infrared Spectrograph (NIRSpec). NG simulates many important noise components including; (1) white "read noise", (2) residual bias drifts, (3) pink 1/f noise, (4) alternating column noise, and (5) picture frame noise. By adjusting the input parameters, NG can simulate noise for Teledyne's H1RG, H2RG, and H4RG detectors with and without Teledyne's SIDECAR ASIC IR array controller. NG can be used as a starting point for simulating astronomical scenes by adding dark current, scattered light, and astronomical sources into the results from NG. NG is written in Python-3.4.

  15. H+ searches in ATLAS (II): H+ to tb

    CERN Document Server

    Mir, Lluisa-Maria; The ATLAS collaboration

    2016-01-01

    A search for charged Higgs bosons heavier than the top quark and decaying via to tb is presented. The analysis uses 13.2 ifb of pp collision data at a centre-of-mass energy of sqrt(s) = 13 TeV collected with the ATLAS detector at the Large Hadron Collider. The production of a charged Higgs boson in association with a top quark and a bottom quark, pp to tbH+-, is explored in the mass range 300 to 1000 GeV using multi-jet final states with one electron or muon from the top-quark decay. Events are categorised according to the multiplicity of jets and b-tagged jets. Multivariate techniques are used to discriminate between signal and background events. No significant excess above the background-only hypothesis is observed and upper limits are set on the tbH+- production cross section times the branching fraction BR(H+- to tb), together with their interpretation in benchmark scenarios of the Minimal Supersymmetric Standard Model.

  16. Low pH Cements

    International Nuclear Information System (INIS)

    Savage, David; Benbow, Steven

    2007-05-01

    The development of low-pH cements for use in geological repositories for radioactive waste stems from concerns over the potential for deleterious effects upon the host rock and other EBS materials (notably bentonite) under the hyperalkaline conditions (pH > 12) of cement pore fluids. Low pH cement (also known as low heat cement) was developed by the cement industry for use where large masses of cement (e.g. dams) could cause problems regarding heat generated during curing. In low pH cements, the amount of cement is reduced by substitution of materials such as fly ash, blast furnace slag, silica fume, and/or non-pozzolanic silica flour. SKB and Posiva have ruled out the use of blast furnace slag and fly-ash and are focusing on silica fume as a blending agent. Currently, no preferred composition has been identified by these agencies. SKB and Posiva have defined a pH limit ≤ 11 for cement grout leachates. To attain this pH, blending agents must comprise at least 50 wt % of dry materials. Because low pH cement has little, or no free portlandite, the cement consists predominantly of calcium silicate hydrate (CSH) gel with a Ca/Si ratio ≤ 0.8. Although there are potential implications for the performance of the spent fuel and cladding due to the presence of hyperalkaline fluids from cement, the principal focus for safety assessment lies with the behaviour of bentonite. There are a number of potential constraints on the interaction of hyperalkaline cement pore fluids with bentonite, including mass balance, thermodynamic issues, mass transport, and kinetics, but none of these is likely to be limiting if conventional OPC cements are employed in repository construction. Nevertheless: Low-pH cements may supply approximately 50 % less hydroxyl ions than conventional OPC for a given volume of cement, but mass balance constraints are complicated by the uncertainty concerning the type of secondary minerals produced during cement-bentonite interaction. The change of aqueous

  17. Low pH Cements

    Energy Technology Data Exchange (ETDEWEB)

    Savage, David; Benbow, Steven [Quintessa Ltd., Henley-on-Thames (United Kingdom)

    2007-05-15

    The development of low-pH cements for use in geological repositories for radioactive waste stems from concerns over the potential for deleterious effects upon the host rock and other EBS materials (notably bentonite) under the hyperalkaline conditions (pH > 12) of cement pore fluids. Low pH cement (also known as low heat cement) was developed by the cement industry for use where large masses of cement (e.g. dams) could cause problems regarding heat generated during curing. In low pH cements, the amount of cement is reduced by substitution of materials such as fly ash, blast furnace slag, silica fume, and/or non-pozzolanic silica flour. SKB and Posiva have ruled out the use of blast furnace slag and fly-ash and are focusing on silica fume as a blending agent. Currently, no preferred composition has been identified by these agencies. SKB and Posiva have defined a pH limit {<=} 11 for cement grout leachates. To attain this pH, blending agents must comprise at least 50 wt % of dry materials. Because low pH cement has little, or no free portlandite, the cement consists predominantly of calcium silicate hydrate (CSH) gel with a Ca/Si ratio {<=} 0.8. Although there are potential implications for the performance of the spent fuel and cladding due to the presence of hyperalkaline fluids from cement, the principal focus for safety assessment lies with the behaviour of bentonite. There are a number of potential constraints on the interaction of hyperalkaline cement pore fluids with bentonite, including mass balance, thermodynamic issues, mass transport, and kinetics, but none of these is likely to be limiting if conventional OPC cements are employed in repository construction. Nevertheless: Low-pH cements may supply approximately 50 % less hydroxyl ions than conventional OPC for a given volume of cement, but mass balance constraints are complicated by the uncertainty concerning the type of secondary minerals produced during cement-bentonite interaction. The change of aqueous

  18. H-Canyon Recovery Crawler

    Energy Technology Data Exchange (ETDEWEB)

    Kriikku, E. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hera, K. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Marzolf, A. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Phillips, M. H. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-08-01

    The Nuclear Material Disposition Project group asked the Savannah River National Lab (SRNL) Research and Development Engineering (R&DE) department to help procure, test, and deploy a remote crawler to recover the 2014 Inspection Crawler (IC) that tipped over in the H-Canyon Air Exhaust Tunnel. R&DE wrote a Procurement Specification for a Recovery Crawler (RC) and SRNS Procurement Department awarded the contract to Power Equipment Manufacturing Inc. (PEM). The PEM RC was based on their standard sewer inspection crawler with custom arms and forks added to the front. The arms and forks would be used to upright the 2014 Inspection Crawler. PEM delivered the RC and associated cable reel, 2014 Inspection Crawler mockup, and manuals in late April 2015. R&DE and the team tested the crawler in May of 2015 and made modifications based on test results and Savannah River Site (SRS) requirements. R&DE delivered the RC to H-Area at the end of May. The team deployed the RC on June 9, 10, and 11, 2015 in the H-Canyon Air Exhaust Tunnel. The RC struggled with some obstacles in the tunnel, but eventually made it to the IC. The team spent approximately five hours working to upright the IC and eventually got it on its wheels. The IC travelled approximately 20 feet and struggled to drive over debris on the air tunnel floor. Unfortunately the IC tripped over trying to pass this obstacle. The team decided to leave the IC in this location and inspect the tunnel with the RC. The RC passed the IC and inspected the tunnel as it travelled toward H-Canyon. The team turned the RC around when it was about 20 feet from the H-Canyon crossover tunnel. From that point, the team drove the RC past the manway towards the new sand filter and stopped approximately 20 feet from the new sand filter. The team removed the RC from the tunnel, decontaminated the RC, and stored it the manway building, 294-2H. The RC deployment confirmed the IC was not in a condition to perform useful tunnel inspections and

  19. 14 CFR Appendix H to Part 36 - Noise Requirements For Helicopters Under Subpart H

    Science.gov (United States)

    2010-01-01

    ... Subpart H H Appendix H to Part 36 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT NOISE STANDARDS: AIRCRAFT TYPE AND AIRWORTHINESS CERTIFICATION Pt. 36, App. H Appendix H to Part 36—Noise Requirements For Helicopters Under Subpart H part a—reference conditions Sec. H36...

  20. Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106

    Energy Technology Data Exchange (ETDEWEB)

    Su, Dan; Hu, Qi; Li, Qing; Thompson, James R; Cui, Gaofeng; Fazly, Ahmed; Davies, Brian A; Botuyan, Maria Victoria; Zhang, Zhiguo; Mer, Georges [Mayo

    2013-04-08

    Dynamic variations in the structure of chromatin influence virtually all DNA-related processes in eukaryotes and are controlled in part by post-translational modifications of histones. One such modification, the acetylation of lysine 56 (H3K56ac) in the amino-terminal α-helix (αN) of histone H3, has been implicated in the regulation of nucleosome assembly during DNA replication and repair, and nucleosome disassembly during gene transcription. In Saccharomyces cerevisiae, the histone chaperone Rtt106 contributes to the deposition of newly synthesized H3K56ac-carrying H3-H4 complex on replicating DNA, but it is unclear how Rtt106 binds H3-H4 and specifically recognizes H3K56ac as there is no apparent acetylated lysine reader domain in Rtt106. Here, we show that two domains of Rtt106 are involved in a combinatorial recognition of H3-H4. An N-terminal domain homodimerizes and interacts with H3-H4 independently of acetylation while a double pleckstrin-homology (PH) domain binds the K56-containing region of H3. Affinity is markedly enhanced upon acetylation of K56, an effect that is probably due to increased conformational entropy of the αN helix of H3. Our data support a mode of interaction where the N-terminal homodimeric domain of Rtt106 intercalates between the two H3-H4 components of the (H3-H4)2 tetramer while two double PH domains in the Rtt106 dimer interact with each of the two H3K56ac sites in (H3-H4)2. We show that the Rtt106-(H3-H4)2 interaction is important for gene silencing and the DNA damage response.

  1. ORION'S BAR: PHYSICAL CONDITIONS ACROSS THE DEFINITIVE H+/H0/H2 INTERFACE

    International Nuclear Information System (INIS)

    Pellegrini, E. W.; Baldwin, J. A.; Ferland, G. J.; Shaw, G.; Heathcote, S.

    2009-01-01

    Previous work has shown the Orion Bar to be an interface between ionized and molecular gas, viewed roughly edge-on, which is excited by the light from the Trapezium cluster. Much of the emission from any star-forming region will originate from such interfaces, so the Bar serves as a foundation test of any emission model. Here we combine X-ray, optical, infrared (IR), and radio data sets to derive emission spectra along the transition from H + to H 0 to H 2 regions. We then reproduce the spectra of these layers with a simulation that simultaneously accounts for the detailed microphysics of the gas, the grains, and molecules, especially H 2 and CO. The magnetic field, observed to be the dominant pressure in another region of the Orion Nebula, is treated as a free parameter, along with the density of cosmic rays. Our model successfully accounts for the optical, IR, and radio observations across the Bar by including a significant magnetic pressure and also heating by an excess density of cosmic rays, which we suggest is due to cosmic rays being trapped in the compressed magnetic field. In the Orion Bar, as we had previously found in M17, momentum carried by radiation and winds from the newly formed stars pushes back and compresses the surrounding gas. There is a rough balance between outward momentum in starlight and the total pressure in atomic and molecular gas surrounding the H + region. If the gas starts out with a weak magnetic field, the starlight from a newly formed cluster will push back the gas and compress the gas, magnetic field, and cosmic rays until magnetic pressure becomes an important factor.

  2. H1 antihistamines and driving.

    Science.gov (United States)

    Popescu, Florin Dan

    2008-01-01

    Driving performances depend on cognitive, psychomotor and perception functions. The CNS adverse effects of some H1 antihistamines can alter the patient ability to drive. Data from studies using standardized objective cognitive and psychomotor tests (Choice Reaction Time, Critical Flicker Fusion. Digital Symbol Substitution Test), functional brain imaging (Positron Emission Tomography, functional Magnetic Resonance Imaging), neurophysiological studies (Multiple Sleep Latency Test, auditory and visual evoked potentials), experimental simulated driving (driving simulators) and real driving studies (the Highway Driving Test, with the evaluation of the Standard Deviation Lateral Position, and the Car Following Test, with the measurement of the Brake Reaction Time) must be discussed in order to classify a H1 antihistamine as a true non-sedating one.

  3. Disease: H00376 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00376 Acute poliomyelitis; Polio Polioviruses are members of the Enterovirus genu...LE ... From emergence to eradication: the epidemiology of poliomyelitis deconstructed. ... JOURNAL ... Am J Epidemiol 172:1213-29 (2010) DOI:10.1093/aje/kwq320 ...s that are transmitted via the hand-to-hand-to-mouth contact. Small proportion of poliovirus infections results in paralytic poliomye...litis due to the viral invasion to central nervous system. The virus destroys lower

  4. Disease: H00372 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00372 Smallpox; Variola Smallpox is a contagious disease caused by the variola vi...al varieties of smallpox: variola major with a case fatality rate of 30% and variola minor with milder severity. Smallpox... millions of people. Infectious disease ... Variola virus [GN:T40082] ... Smallpox vaccine [DR:D05295] ... ICD-10: ...URNAL ... Dev Biol Stand 100:31-7 (1999) ... PMID:9795781 (description, env_factor) ... AUTHORS ... Ellner PD ... TITLE ... Smallpox

  5. Disease: H01640 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01640 Uterine leiomyoma; Fibroid Uterine leiomyoma, also known as fibroid, is the...ing combined with previous knowledge have led to an emerging molecular classification of leiomyoma...s, suggesting that there are several distinct pathogenic pathways involved in leiomyoma for...mation. The evidence points to at least 4 molecular subclasses: leiomyomas with MED12 mutation, FH inactivat...he initial events that trigger leiomyoma tumorigenesis involves somatic mutations, it is evident that the de

  6. Disease: H01238 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01238 Phelan-McDermid syndrome; Chromosome 22q13.3 deletion syndrome Phelan-McDer...mid syndrome is a genetic disorder caused by a microdeletion on chromosome 22. It is characterized by severe...t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome. ... JOURNAL ... Am J Hum Genet 69:261-8 (2001) DOI:10.1086/321293

  7. Disease: H01221 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01221 Epithelial basement membrane corneal dystrophy (EBMD); Cogan microcystic ep...ithelial dystrophy; Map-dot-fingerprint dystrophy Epithelial basement membrane corneal dystrophy (EBMD) is a...e known to cause various forms of corneal dystrophies, have been identified. Sheet-like areas of basement me...on J, Menasche M, Munier FL, Laroche L, Abitbol M, Schorderet DF ... TITLE ... A subset of patients with epithelial basemen

  8. Disease: H01542 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01542 Bolivian hemorrhagic fever Bolivian hemorrhagic fever (BHF) is highly letha... during outbreaks affecting isolated human communities in eastern Bolivia. Initia...Grant A, Paessler S ... TITLE ... Epidemiology and pathogenesis of Bolivian hemorrh...redes LC, Peters CJ ... TITLE ... Treatment of Bolivian hemorrhagic fever with intravenous ribavirin. ... JOURNAL ... Clin Infect Dis 24:718-22 (1997) DOI:10.1093/clind/24.4.718

  9. Disease: H01027 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01027 Anophthalmia and microphthalmia (A/M); Nanophthalmia/ Nanophthalmos Anophth...BP4 [HSA:5950] [KO:K18271] (isolated) RAX [HSA:30062] [KO:K09332] (isolated/nanophthalmia) MFRP [HSA:83552] ...(isolated) PRSS56 [HSA:646960] (isolated) ALDH1A3 [HSA:220] [KO:K00129] (nanophthalmia...ent misuse ... Simple microphthalmia refers to a structurally normal, small eye, and has been used interchangeably with nanophthalmia

  10. Disease: H01739 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01739 Polycystic ovary syndrome Polycystic ovary syndrome (PCOS) is a common hete...d frequently infertility. Clinical signs of PCOS include elevated luteinizing hor...rn, produces more androgens. Risk factors for PCOS in adults includes insulin res...istance (IR), type 2 diabetes, obesity, and cardiovascular disease. PCOS can be described as an oligogenic d...s, clinical, and biochemical phenotype. Management of clinical manifestations of PCOS

  11. Disease: H01680 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01680 Chronic pancreatitis Chronic pancreatitis is a progressive inflammatory dis...ease of the pancreas that will finally result in both exocrine and endocrine insufficiency. Chronic pancreatitis...tes. Six major etiologies for chronic pancreatitis have been identified, namely toxic-metabolic (to include ...alcohol), idiopathic, genetic, autoimmune, recurrent and severe acute pancreatitis..., and obstruction. Oral protease inhibitors are currently used as a medical treatment for chronic pancreatitis

  12. Disease: H00535 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00535 Lymphedemas, including: Lymphedema, hereditary I; Lymphedema-distichiasis s...yndrome; Hypotrichosis-lymphedema-telangiectasia syndrome (HLTS); Hennekam syndrome Lymphoedemas are develop... The dilated lymphatic channels that are not connected to the lymphatic vessels cause these edema...s. LD patients develop extra eyelashes, Hypotrichosis-lymphedema-telangiectasia syndrome (HL...TS) is associated with sparse hair and cutaneous telangiectasias, and Hennekam lymphangiectasia-lymphedema s

  13. Disease: H00713 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00713 Beckwith-Wiedemann syndrome Beckwith-Wiedemann syndrome (BWS) is an imprint...CD-10: Q87.3 MeSH: D001506 OMIM: 130650 PMID:20803657 ... AUTHORS ... Choufani S, Shuman C, Weksberg R ... TITLE ... Beckwith-Wiedema...ajmg.c.30267 ... PMID:19407494 ... AUTHORS ... Eggermann T ... TITLE ... Silver-Russell and Beckwith-Wiedema...re V, Colleaux L ... TITLE ... Paradoxical NSD1 mutations in Beckwith-Wiedemann syndrome and 11p15 anomalies i

  14. Disease: H01006 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01006 Hereditary angioedema Hereditary angioedema (HAE) is a rare genetic disorde...r, manifested by recurrent episodes of angioedema localized to the skin or mucosa of the gastrointestinal tr...act or larynx. The laryngeal angioedema is potentially lethal. The classic forms, HAE types I and II, result...6100 PMID:14572810 (description, gene) ... AUTHORS ... Davis AE 3rd ... TITLE ... The pathogenesis of hereditary angioedema... (drug) ... AUTHORS ... Antoniu SA ... TITLE ... Therapeutic approaches in hereditary angioedema. ... JOURNAL ... Clin

  15. Disease: H01287 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01287 Congenital mirror movements (CMM) Mirror movements are involuntary movement...s of one side of the body that mirror intentional movements on the opposite side. While mirror movements are... occasionally found in young children, persistence beyond the age of 10 is abnormal. Congenital mirror movement...ions in DCC cause congenital mirror movements. ... JOURNAL ... Science 328:592 (2010) DOI:10.1126/science.1186463 ...

  16. Disease: H01535 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01535 Eastern equine encephalitis Eastern equine encephalitis virus (EEEV) is imp...o, Culiseta melanura. Eastern equine encephalitis is the most severe neuroinvasiv...e arboviral infection in the United States, frequently progressing to coma and death. Infectious disease ... Eastern equine...eaver SC ... TITLE ... Evolutionary patterns of eastern equine encephalitis virus in North versus South Americ...D, Hassan HK, McClure CJ, Unnasch TR ... TITLE ... Field investigations of winter transmission of eastern equine

  17. Disease: H00342 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00342 Tuberculosis Tuberculosis is a infectious disease caused by strains of myco...aking pulmonary tuberculosis the most common form of tuberculosis. Tuberculosis m...THORS ... De Backer AI, Mortele KJ, De Keulenaer BL, Parizel PM ... TITLE ... Tuberculosis...43-50 (2006) ... PMID:21420161 (description) ... AUTHORS ... Lawn SD, Zumla AI ... TITLE ... Tuberculosis. ... JOURNAL ... Lancet 378:57-72 (2011) DOI:10.1016/S0140-6736(10)62173-3

  18. Disease: H00680 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00680 Primary failure of tooth eruption Primary failure of tooth eruption (PFE) i...al features and aetiological basis of primary eruption failure. ... JOURNAL ... Eur J Orthod 28:535-40 (2006) DO...of-function mutations in familial, nonsyndromic primary failure of tooth eruption. ... JOURNAL ... Am J Hum Genet 83:781-6 (2008) DOI:10.1016/j.ajhg.2008.11.006

  19. Disease: H00991 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00991 Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Microc...ephalic osteodysplastic primordial dwarfism, type II (MOPD II) is an autosomal recessive condition character...lic osteodysplastic primordial dwarfism, type I (MOPD I). ICD-10: Q87.1 MeSH: C56... ... TITLE ... Majewski osteodysplastic primordial dwarfism type II (MOPD II): natural history and clinical fi... gene (PCNT) in a series of 24 Seckel/microcephalic osteodysplastic primordial dwarfism

  20. Disease: H00993 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00993 Microcephalic osteodysplastic primordial dwarfism, type I (MOPD I); Taybi-L...inder syndrome Microcephalic osteodysplastic primordial dwarfism, type I (MOPD I) is a condition comprising ...halic osteodysplastic primordial dwarfism, type II (MOPD II). ICD-10: Q87.1 MeSH:...se of microcephalic osteodysplastic primordial dwarfism type I (MOPD I) with associated pigmentary disorder. ... JOURNAL ... Am J Med Genet A 155A:2885-96 (2011) DOI:10.1002/ajmg.a.34299 ...

  1. Disease: H00992 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00992 Seckel syndrome Seckel syndrome is a recessively inherited dwarfism charact...erized by intrauterine growth retardation, proportionate postnatal dwarfism, severe microcephaly, micrognath...Baron J, Rosenfeld RG, Hirschhorn JN, Harris MP, Hwa V ... TITLE ... Novel microcephalic primordial dwarfism d...ion and is mutated in primordial dwarfism. ... JOURNAL ... Nat Genet 48:36-43 (2016) DOI:10.1038/ng.3451

  2. Disease: H01479 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available cilizumab is a monoclonal antibody directed against the IL-6 receptor, and siltuximab is a monoclonal antibo...ed serum amyloid A (SAA) and C-reactive protein (CRP) Tocilizumab [DR:D02596] Siltuximab [DR:D09669] ... ICD-10...nial S, Borghaei H, Sokol L, Crawford J, Cornfeld M, Qi M, Qin X, Herring J, Casper C, Kurzrock R ... TITLE ... Siltux

  3. Disease: H01203 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01203 Primary congenital glaucoma (PCG) Primary congenital glaucoma (PCG) is a severe form of glaucoma...LTBP2 [HSA:4053] [KO:K08023] ... Surgery for glaucoma: goniotomy, goniopuncture, ... SA ... TITLE ... Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma... AUTHORS ... Sharaawy T, Bhartiya S ... TITLE ... Surgical management of glaucoma: evolving paradigms. ... JOURNAL ... Indian J Ophthalmol 59 Suppl:S123-30 (2011) DOI:10.4103/0301-4738.73692

  4. Disease: H00066 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00066 Lewy body dementia (LBD); Dementia with Lewy bodies (DLB) Lewy Body dementia... (LDB) is neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in atten...tion and alertness. It is the second most-common degenerative dementia after Alzheimer's disease. Progressiv...t advances in the genetics of dementia with lewy bodies. ... JOURNAL ... Curr Neurol Neurosci Rep 8:187-9 (2008)

  5. Disease: H00589 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00589 Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy... 1 (EVR1); Exudative vitreoretinopathy2, X-linked ... (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy... 5 (EVR5); Norrie disease (ND) Familial exudative vitreoretinopathy (FEVR) and Norri...RP5 [HSA:4041] [KO:K03068] (EVR5) TSPAN12 [HSA:23554] [KO:K17355] ... Exudative vitreoretinopathy 3 (EVR3) ...ion spectrum in familial exudative vitreoretinopathy and Norrie disease with iden

  6. Disease: H01880 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01880 Autosomal recessive microcephaly and chorioretinopathy Autosomal-recessive ...ent in MCCRP patients are variable, but the chorioretinopathy is a constant feature and includes typical pun...ark DB ... TITLE ... Chorioretinopathy with hereditary microcephaly. ... JOURNAL ... Arch Ophthalmol 75:597-600 (1... autosomal recessive microcephaly and chorioretinopathy. ... JOURNAL ... Eur J Hum Genet 24:1702-1706 (2016) DOI... ... Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

  7. Disease: H01331 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01331 Dental caries; Dental decay Dental caries occurs due to demineralization of...ough the anaerobic metabolism of sugars derived from the diet. The 2 primary bacteria involved in caries for...es associated with dental caries in Thai preschool children. ... JOURNAL ... Mol Oral Microbiol 25:157-64 (2010) DOI:10.1111/j.2041-1014.2009.00556.x

  8. Disease: H00741 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00741 Ichthyosis prematurity syndrome Ichthyosis prematurity syndrome is a form o...onnevig J, Johnsson M, Sitek JC, Blaas HG, Hausser I, Johansen FE, Jahnsen FL ... TITLE ... Ichthyosis prematurity...e cause the ichthyosis prematurity syndrome. ... JOURNAL ... Am J Hum Genet 85:248-53 (2009) DOI:10.1016/j.ajhg.2009.06.021 ...Dahl N, Fischer J ... TITLE ... Mutations in the fatty acid transport protein 4 gen

  9. Disease: H00791 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00791 Disseminated superficial actinic porokeratosis (DSAP) Porokeratosis is a di...amella. Disseminated superficial actinic porokeratosis (DSAP) is the most common form of porokeratosis. It i... (description) ... AUTHORS ... Sertznig P, von Felbert V, Megahed M ... TITLE ... Porokeratosis...isseminated superficial actinic porokeratosis in a patient undergoing treatment w...eminated superficial and warty type of porokeratosis: a rare coexistence. ... JOURNAL ... Indian J Dermatol 56:576-7 (2011) DOI:10.4103/0019-5154.87160 ...

  10. Disease: H00806 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00806 Benign familial neonatal and infantile epilepsies, including: Benign familial neonatal epilepsy... (BFNE); Benign familial neonatal infantile epilepsy (BFNIE); Benign familial infantile epilepsy... (BFIE) Benign familial neonatal epilepsy (BFNE), benign familial neonatal infantile epilepsy (BFNIE...), and benign familial infantile epilepsy (BFIE) are three benign epilepsy syndro...LE ... Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy. ... JOURNAL ... Brain 133:1403-14 (2010) DOI:10.1093/brain/awq057

  11. Disease: H01251 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01251 Focal cortical dysplasia of Taylor; Focal cortical dysplasia ... type II Focal...iestler OD, Blumcke I ... TITLE ... Focal cortical dysplasia of Taylor's balloon ce...icopathologic subtypes of cortical dysplasia of Taylor. ... JOURNAL ... Neurology 64:55-61 (2005) DOI:10.1212/01.WNL.0000148647.55705.A3 ... ... cortical dysplasia of Taylor (FCDT) is a subtype of cortical displasias. FCDT is characterized by epilepsy

  12. Disease: H01858 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01858 Persistent cloaca Persistent cloaca is an uncommon congenital anomaly in wh... most severe form of anorectal malformation encountered in girls. The incidence is approximately 1 in 50,000 live births. Persistent...r gastrointestinal anomalies are often associated with persistent cloaca. Moreover, anomalies of other organ... systems such as cardiac or skeletal malformations are known to coexist. The common channel of persistent... A new approach for persistent cloaca: Laparoscopically assisted anorectoplasty and modified repair of uroge

  13. Disease: H01209 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01209 Deafness, X-linked Hereditary deafness is divided into syndromic forms (in which hearing... of the cases of non-syndromic hearing loss. X-linked deafness is clinically and genetically heterogeneous d...isorder. PRPS1 and POU3F4 have been identified as the genes to be implicated in X-linked non-syndromic hea...ring loss. Nervous system disease; Nervous system disease PRPS1 [HSA:5631] [KO:K009

  14. Disease: H01704 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01704 Sudden sensorineural hearing loss Sudden sensorineural hearing loss (SNHL) ... for recovery is dependent on a number of factors, including patient age, presence of vertigo at onset, degree of hearing... loss, and time between onset of hearing loss and treatment. The pat...apy and ozone therapy in sudden hearing loss. ... JOURNAL ... Braz J Otorhinolaryngol...is commonly defined as hearing loss of more than 30 dB, affecting three or more frequencies, arising over le

  15. Disease: H00997 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available TLE ... A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome. ... JOURNAL ... Am J Hum Genet 79:935-41 (2006) DOI:10.1086/508433 ... H00997 CATSHL syndrome CATSHL syndrome is characterised by camptodactyly, tall stature, scoliosis, and hear...ing loss. The syndrome is caused by a missense mutation in the FGFR3 gene. FGFR3 is

  16. Disease: H00250 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00250 Congenital nongoitrous hypothyroidism (CHNG) Congenital nongoitrous hypothyroidism...ing can avoid the poor prognosis of hypothyroidism. Endocrine disease (CHNG1) TSH... on the management of congenital hypothyroidism. ... JOURNAL ... Horm Res 68 Suppl 5:107-11 (2007) DOI:10.1159/0...00110591 ... PMID:15863666 ... AUTHORS ... Park SM, Chatterjee VK ... TITLE ... Genetics of congenital hypothyroidi...sm. ... JOURNAL ... J Med Genet 42:379-89 (2005) DOI:10.1136/jmg.2004.024158 ... PMID:2567

  17. Disease: H01647 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01647 Subacute thyroiditis; Subacute granulomatous thyroiditis; De Quervain thyroiditis Subacute thyroidit...is (SAT), also called subacute granulomatous or de Quervain thyroiditis, is a spont... ... Karachalios GN, Amantos K, Kanakis KV, Deliousis A, Karachaliou IG, Zacharof AK ... TITLE ... Subacute thyroiditis...aneously remitting, painful, inflammatory disease of the thyroid gland, which is considered the most common cause of painful thyroidi...tis. It is an uncommon but important cause of fever of u

  18. Disease: H00982 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00982 Sideroblastic anemia, including: Pyridoxine-refractory autosomal recessive sideroblastic anemia... (PRARSA); X-linked sideroblastic anemia (XLSA); X-linked sideroblastic anemia with atax...ia (ASAT) Sideroblastic anemias are a group of disorders characterized by anemia with the emergence of ring ...sideroblasts in the bone marrow. Inherited sideroblastic anemia is a rare and het..., Furuyama K ... TITLE ... Hereditary sideroblastic anemia: pathophysiology and gen

  19. Disease: H01184 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01184 Familial dementia, including: Familial British dementia (FBD); Familial Danish dementia... (FDD) Familial British dementia (FBD) and familial Danish dementia (FDD) are two autosomal domi...nant neurodegenerative diseases caused by mutations in the BRI/ ITM2B gene. Familial dementia is characteriz... ... TITLE ... Modeling familial British and Danish dementia. ... JOURNAL ... Brain Struct Funct 214:235-44 (2010) DOI:10.1007/s00429-009-0221-9

  20. Disease: H01622 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01622 Chronic thromboembolic pulmonary hypertension Chronic thromboembolic pulmonary hypertension... (CTEPH) is classified as group 4 pulmonary hypertension (PH) by the World Health Organizati...he development of a distal vessel arteriopathy that closely mimics pulmonary arterial hypertension. ... While t...2] ... ICD-10: I27.2 PMID:26739298 (drug) ... AUTHORS ... Poch DS, Auger WR ... TITLE ... Chronic thromboembolic pulmonary hypertension...iption, drug) ... AUTHORS ... Robbins IM, Pugh ME, Hemnes AR ... TITLE ... Update on chronic thromboembolic pulmonary hypertension

  1. Disease: H01619 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01619 Primary pulmonary hypertension (PPH) Primary pulmonary hypertension (PPH) i...THORS ... Gaine SP, Rubin LJ ... TITLE ... Primary pulmonary hypertension. ... JOURNAL ... Lancet 352:719-25 (1998) ...AUTHORS ... Rudarakanchana N, Morrell NW ... TITLE ... Primary pulmonary hypertension: molecular basis and poten...(drug) ... AUTHORS ... Nagaya N ... TITLE ... Drug therapy of primary pulmonary hypertension. ... JOURNAL ... Am J Cardiovasc Drugs 4:75-85 (2004)

  2. Disease: H01358 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01358 Atopic dermatitis Atopic dermatitis (AD) is a relapsing chronic inflammator...recent genome-wide association studies (GWASs) ... have identified many susceptibility loci of atopic dermatiti...PMID:23473856 (gene, description) ... AUTHORS ... Kabashima K ... TITLE ... New concept of the pathogenesis of atopic... ... Bussmann C, Weidinger S, Novak N ... TITLE ... Genetics of atopic dermatitis. ... JOURNAL ... J Dtsch Dermatol ...ngh A, Guralnick M ... TITLE ... Atopic dermatitis: an overview. ... JOURNAL ... Am Fam Physician 86:35-42 (2012)

  3. Disease: H01142 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01142 Ehrlichia ewingii infection Human ehrlichiosis is a recently recognized tic...k-borne infection. Ehrlichia ewingii has been identified as a cause of human disease in addition to formerly... known pathogenic Ehrlichia species. Infectious disease ... Ehrlichia ewingii ... 16S rRNA [KO:K01977] ... Other dis... Manian FA, Liddell AM, Schmulewitz N, Storch GA ... TITLE ... Ehrlichia ewingii, a

  4. Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin.

    Science.gov (United States)

    Qi, Li; Pujanauski, Lindsey M; Davis, A Sally; Schwartzman, Louis M; Chertow, Daniel S; Baxter, David; Scherler, Kelsey; Hartshorn, Kevan L; Slemons, Richard D; Walters, Kathie-Anne; Kash, John C; Taubenberger, Jeffery K

    2014-11-18

    Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric 1918 virus expressing a contemporary avian H1 hemagglutinin, however, displayed murine pathogenicity indistinguishable from that of the 1918 virus. Here, isogenic chimeric avian influenza viruses were constructed on an avian influenza virus backbone, differing only by hemagglutinin subtype expressed. Viruses expressing the avian H1, H6, H7, H10, and H15 subtypes were pathogenic in mice and cytopathic in normal human bronchial epithelial cells, in contrast to H2-, H3-, H5-, H9-, H11-, H13-, H14-, and H16-expressing viruses. Mouse pathogenicity was associated with pulmonary macrophage and neutrophil recruitment. These data suggest that avian influenza virus hemagglutinins H1, H6, H7, H10, and H15 contain inherent mammalian virulence factors and likely share a key virulence property of the 1918 virus. Consequently, zoonotic infections with avian influenza viruses bearing one of these hemagglutinins may cause enhanced disease in mammals. Influenza viruses from birds can cause outbreaks in humans and may contribute to the development of pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its main surface protein, an H1 subtype hemagglutinin, was identified as a key mammalian virulence factor. In a previous study, a 1918 virus expressing an avian H1 gene was as virulent in mice as the reconstructed 1918 virus. Here, a set of avian influenza viruses was constructed, differing only by hemagglutinin subtype. Viruses with the avian H1, H6, H7, H10, and H15 subtypes caused severe disease in mice and damaged human lung cells. Consequently, infections with avian influenza viruses bearing one of these hemagglutinins may cause enhanced disease in mammals, and therefore surveillance for human infections

  5. H3 internationalization to Brazil

    OpenAIRE

    Carona, Eduardo João Bonneville Torres

    2012-01-01

    A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics h3 is a Portuguese firm competing in the fast food market with a hamburger gourmet concept. The firm is now a strong player in Portugal (39 stores); Poland, Warsaw (1 store); Spain, Madrid (1 store) and Brazil, São Paulo (2 stores). As a result of their successes in the domestic market, internationalization was a natural step. One o...

  6. Disease: H00688 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00688 Familial advanced sleep phase syndrome Familial advanced sleep phase syndro...me (FASPS) is characterized by a stable sleep schedule with a 4-hour advance than the conventional or desire...Barion A ... TITLE ... Circadian rhythm sleep disorders. ... JOURNAL ... Dis Mon 57:423...S, Zone SE, Cooper F, DeSano A, Murphy PJ, Jones B, Czajkowski L, Ptacek LJ ... TITLE ... Familial advanced sleep...idelta mutations in familial migraine and advanced sleep phase. ... JOURNAL ... Sci Transl Med 5:183ra56, 1-11 (2013) DOI:10.1126/scitranslmed.3005784 ...

  7. Disease: H00689 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00689 Delayed sleep phase syndrome Delayed sleep phase disorder is characterized ...by a 3 to 6-hour delayed sleep schedule relative to the desired. The single nucleotide polymorphism (Ala129T...dentified in patients with delayed sleep phase disorder. Sleep disorder AANAT (po...rion A ... TITLE ... Circadian rhythm sleep disorders. ... JOURNAL ... Dis Mon 57:423-37 (2011) DOI:10.1016/j.disa...sferase ( AA-NAT) gene with delayed sleep phase syndrome. ... JOURNAL ... Neurogenetics 4:151-3 (2003) DOI:10.1007/s10048-002-0141-9

  8. Disease: H01792 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01792 1p36 deletion syndrome 1p36 deletion syndrome is is a recently delineated d...isorder, considered to be the most common subtelomeric microdeletion syndrome. 1p36 deletion syndrome is cha...g affected individuals. This variation is due, at least in part, to the genetic heterogeneity seen in 1p36 deletion...s which include terminal and interstitial deletions of varying lengths. Ch... ... AUTHORS ... Jordan VK, Zaveri HP, Scott DA ... TITLE ... 1p36 deletion syndrome: an update. ... JOURNAL ... Appl C

  9. Disease: H01525 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01525 22q11.2 deletion syndrome; DiGeorge/ Velo-Cardio-Facial syndrome; CATCH22 The 22q11.2 deletion... syndrome is the most common microdeletion disorder with an estimated prevalence of 1 in ...3000-6000 live births. Most of the patients show the common 3 Mb deletion, but proximal 1.5 Mb deletion and unusual deletion...Various syndromes have been associated with 22q11.2 deletion including DiGeorge syndrome (DGS), velocardiofa...cular malformation. Microdeletions of 22q11.2 have been found in more than 90% of

  10. Disease: H01877 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01877 Chromosome 15q13.3 microdeletion syndrome Chromosome 15q13.3 microdeletion ...syndrome causes a spectrum of cognitive disorders. The syndrome is caused by microdeletions in the 15q13.2q-...and attention deficit hyperactivity disorder (ADHD). The neuropsychiatric phenotypes of 15q13.3 microdeletion...ognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome. ... JOURNAL ... J Autism Dev Disord 46:1455-63 (2016) DOI:10.1007/s10803-015-2694-0 ...

  11. Disease: H00469 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00469 Mitochondrial DNA depletion syndrome (MDS) Mitochondrial DNA depletion synd...n mitochondrial DNA in the affected tissues. The manifestations vary from tissue-specific mtDNA depletion to...5400 221350 615084 615418 615471 617156 PMID:20444604 ... AUTHORS ... Suomalainen A, Isohanni P ... TITLE ... Mitochondrial DNA depletion...drial transcription factor A, cause neonatal liver failure associated with mtDNA depletion. ... JOURNAL ... Mol Genet Metab 119:91-9 (2016) DOI:10.1016/j.ymgme.2016.07.001

  12. Disease: H01698 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available cell arteritis and large vessel vasculitis. ... JOURNAL ... RMD Open 2:e000137 (2016) DOI:10.1136/rmdopen-2015-000137 ...s of C-reactive protein (CRP) Glucocorticoids Tocilizumab [DR:D02596] See also H01465 Large-vessel vasculi...culitis in individuals over the age of 50 in Western countries. It is characterized...nown as temporal arteritis, is a chronic and polygenic immune-mediated disease of unknown etiology. It is the most common form of vas...tis (LVV). ICD-10: M31.6 MeSH: D013700 OMIM: 187360 PMID:27708947 (marker) ... AUTHOR

  13. Disease: H00582 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00582 Benign familial hematuria; Thin basement membrane nephropathy Benign famili...hildhood. The glomerular basement membrane is uniformly thin, but renal function is normal. Heterozygous mut...ations in COL4A3 or COL4A4 lead to reduced collagen network levels in the basemen...MIM: 141200 PMID:18094725 (gene, description) ... AUTHORS ... Gubler MC ... TITLE ... Inherited diseases of the glomerular basemen...Wang YY ... TITLE ... Thin basement membrane nephropathy. ... JOURNAL ... Kidney Int 64:1169-78 (2003) DOI:10.1046/j.1523-1755.2003.00234.x

  14. Disease: H00388 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00388 Non-chlamydial non-gonococcal urethritis Urethritis in men is one of the mo...iae, has been implicated in non-chlamydial non-gonococcal urethritis. Moreover, it is linked to several infl...asuda M, Maeda S ... TITLE ... [Non-chlamydial non-gonococcal urethritis] ... JOURNAL ... Nippon Rinsho 67:167-71 ...a S, Deguchi T ... TITLE ... Mycoplasma genitalium urethritis in men. ... JOURNAL ... Int J Antimicrob Agents 24 Suppl 1:S23-7 (2004) DOI:10.1016/j.ijantimicag.2004.02.006 ...

  15. Disease: H01553 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01553 Zika fever; Zika virus disease Zika fever is one of the mosquito-borne viral fevers caused by Zika...n to human through bites of Aedes species. ZIKV was initially distinguished in rhesus monkeys in the Zika fo...etween microcephaly and of Zika virus. It has been reported that ZIKV-infected children, who were born to ZI...nces below the 10th percentile. Infectious disease ... Zika virus [GN:T40049] ... Serodiagnosis by IgM ELISA test... AUTHORS ... Maharajan MK, Ranjan A, Chu JF, Foo WL, Chai ZX, Lau EY, Ye HM, Theam

  16. Disease: H00932 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00932 Tropical calcific pancreatitis Tropical calcific pancreatitis (TCP) is a subtype of chronic pancreat...rrent abdominal pain, nutritional deficiencies, and insulin-requiring diabetes resulting from chronic pancreatitis...tia E ... TITLE ... Genetic aspects of tropical calcific pancreatitis. ... JOURNAL ... Rev Endocr Metab Disord 9:2... Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis. ... JOURNAL ... Pancreatology 9...associated with chronic pancreatitis. ... JOURNAL ... Nat Genet 40:78-82 (2008) DOI:10.1038/ng.2007.44 ...

  17. Disease: H00393 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ) Enterovirus B [GN:T40104] Enterovirus C [GN:T40105] Enterovirus D [GN:T40106] Human echovirus 1 Human enterovirus...ong SC, Lewthwaite P, Cardosa MJ, Solomon T ... TITLE ... Clinical features, diagnosis, and management of enterovirus...Epidemiologic features of hand-foot-mouth disease and herpangina caused by enterovirus 71 in Taiwan, 1998-2005. ... JOURNAL ... Pediatrics 120:e244-52 (2007) DOI:10.1542/peds.2006-3331 ...se RNA viruses from the enterovirus genus in the family Picornaviridae. They are major public health issues ... H00393 Enterovirus infection Enteroviruses (EVs) are single-stranded, positive-sen

  18. Disease: H01651 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01651 Macular edema Macular edema is a common feature of many diseases of the ret...the intraretinal area or collects in the subretinal space. In more severe cases, it occurs as cystoid edema ...with the typical petaloid appearance, and is the leading cause of visual loss. New treatments for macular edema...AUTHORS ... Rotsos TG, Moschos MM ... TITLE ... Cystoid macular edema. ... JOURNAL ... Clin Ophthalmol 2:919-30 (200...8) ... PMID:27256304 ... AUTHORS ... Fardeau C, Champion E, Massamba N, LeHoang P ... TITLE ... Uveitic macular edema. ... JOURNAL ... Eye (Lond) 30:1277-1292 (2016) DOI:10.1038/eye.2016.115 ...

  19. Double hypernuclei or H particles?

    International Nuclear Information System (INIS)

    May, M.

    1996-01-01

    We will begin with the H particle, stranglets and strange matter since these proposed objects are a strong motivation for studying hypernuclei containing two strange quarks. The data on ΛΛ and Ξ hypernuclei will then be reviewed, as well as experiments in progress or scheduled. Many have contributed to the work that will be discussed, which took place primarily at KEK and BNL. At this time of transition, and anticipation of new experimental results and facilities, we take time to remember Carl Dover and Hiro Bando who contributed so much to this field

  20. Disease: H01882 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01882 Asperger syndrome Asperger syndrome (AS), a behavioral disorder that is related to autism...eron T ... TITLE ... Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. ... JOURNAL ... Nat Genet 34:27-9 (2003) DOI:10.1038/ng1136 ...entified. Recent studies have suggested that the mutations in two X-linked genes, neuroligins NLGN3 and NLGN4 are associated with aut...ism and AS. Mental disorder NLGN3 [HSA:54413] [KO:K07378] NLGN4 [HSA:57502] [KO:K07

  1. Disease: H01429 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01429 Aseptic meningitis The term aseptic meningitis can be used broadly to include all types of meningiti...s with negative bacterial cultures from cerebrospinal fluid. Etiology of aseptic meningitis... is very wide and includes both viral and non-viral infections, drugs, malignancy, and systemic illness. Viral meningitis... constitutes the most common cause of aseptic meningitis and...Kumar R ... TITLE ... Aseptic meningitis: diagnosis and management. ... JOURNAL ... Indian J Pediatr 72:57-63 (2005) DOI:10.1007/BF02760582 ...

  2. Disease: H01313 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01313 Escherichia coli meningitis; Neonatal meningitis-associated Escherichia col...i (NMEC) infection Escherichia coli meningitis is a bacterial meningitis caused by Escherichia coli, and is ...common in the newborn within the first month of life (neonatal meningitis). Neonatal meningitis-associated E...e genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10. ... JOURNAL ... J Bacteriol 193:7005 (2011) DOI:10.1128/JB.06284-11 ...ngitis. Infectious disease ... Escherichia coli (NMEC) [GN:eoc ecz eih] ... ICD-10: G

  3. Disease: H01547 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01547 Venezuelan equine fever Venezuelan equine fever is one of the mosquito-born...e viral fevers. The disease is caused by Venezuelan equine encephalitis virus (VEEV), an alphavirus that is ...transmitted by Ochlerotatus mosquitoes. VEEV is the most important human and equine pathogen. VEEV has cause...ometimes followed by death. Infectious disease ... Venezuelan equine encephalitis virus [GN:T40028] ... Serodiagn... fevers. ICD-10: A92.2 MeSH: D004685 PMID:23968890 ... AUTHORS ... Taylor KG, Paessler S ... TITLE ... Pathogenesis of Venezuelan equine

  4. Disease: H00377 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00377 Rabies Rabies is an old zoonotic disease which has been known for more than...om it. Dogs are the major vectors. Rabies affects the central nervous system and causes fatal encephalomyeli...Africa die every year due to rabies. Infectious disease ... Rabies virus (RABV) [GN:T40022] ... Rabies vaccine [DR:D06504 D05248] Rabies... ... Yousaf MZ, Qasim M, Zia S, Khan Mu, Ashfaq UA, Khan S ... TITLE ... Rabies molecular virology, diagnosis, p... ... Leung AK, Davies HD, Hon KL ... TITLE ... Rabies: epidemiology, pathogenesis, and prophylaxis. ... JOURNAL ... Adv Ther 24:1340-7 (2007) DOI:10.1007/BF02877781

  5. Disease: H00056 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00056 Alzheimer's disease (AD) Alzheimer's disease (AD) is a chronic disorder tha...sak JM, Holtzman DM ... TITLE ... The role of apolipoprotein E in Alzheimer's disease. ... JOURNAL ... Neuron 63:2...87-303 (2009) DOI:10.1016/j.neuron.2009.06.026 ... PMID:18802446 ... AUTHORS ... Bertram L, Tanzi RE ... TITLE ... Thirty years of Alzheimer...Cacabelos R ... TITLE ... Pharmacogenomics in Alzheimer's disease. ... JOURNAL ... Methods Mol Biol 448:213-357 (2...008) DOI:10.1007/978-1-59745-205-2_10 ... PMID:17082447 ... AUTHORS ... Goedert M, Spillantini MG ... TITLE ... A century of Alzheimer

  6. Disease: H00627 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00627 Premature ovarian failure Premature ovarian failure (POF) is characterized ...tal causes, medical intervention including surgeries and chemotherapies may lead to POF. Autoimmune ovarian failure... ... Research on the mechanisms of premature ovarian failure. ... JOURNAL ... J Soc Gynecol Investig 8:S10-2 (2001...the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: eviden...vic A ... TITLE ... NOBOX homeobox mutation causes premature ovarian failure. ... JOURNAL ... Am J Hum Genet 81:576-81 (2007) DOI:10.1086/519496

  7. Disease: H01631 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01631 Acute heart failure Acute heart failure (AHF) can be defined as a heterogen...eous syndrome of signs and symptoms of new-onset or gradual/rapidly worsening heart failure (HF), requiring ...J, O'Connor CM ... TITLE ... Pathophysiology and clinical evaluation of acute heart failure. ... JOURNAL ... Nat R... ... AUTHORS ... Chowdhury P, Kehl D, Choudhary R, Maisel A ... TITLE ... The use of biomarkers in the patient with heart failure...g) ... AUTHORS ... Poss J, Link A, Bohm M ... TITLE ... Pharmacological treatment of acute heart failure

  8. Disease: H01656 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01656 Psoriasis Psoriasis is a chronic, immune-mediated inflammatory skin disease...nvironmental factors, and immune disorders play an important role in causing psoriasis. Psoriasis is associa...ted with several comorbidities, including cardiovascular disease, lymphoma, and depression. Psoriasis is an ...escription, drug) ... AUTHORS ... Burfield L, Burden AD ... TITLE ... Psoriasis. ... JOUR...tion) ... AUTHORS ... Limaye K ... TITLE ... Psoriasis: an overview and update. ... JOURNAL ... Nurse Pract 40:23-6 (2015) DOI:10.1097/01.NPR.0000453651.30695.43

  9. Quadruple H therapy for vasospasm

    Directory of Open Access Journals (Sweden)

    Walid M

    2009-01-01

    Full Text Available Triple H therapy has been enthusiastically used to increase cerebral blood flow in cases of vasospasm. Nevertheless, the oxygen-carrying capacity of the blood is lowered with this treatment. This side effect can theoretically be partially corrected using hyperbaric oxygen therapy (HBO which appears to be the missing ring in the above therapeutic regimen. We conducted a review of of the available evidence regarding the beneficial effects of HBO in preventing postoperative ischemic complications due to vasospasm after surgery on ruptured cerebral aneurysms and the rationale for including HBO into the standards of care of these difficult patients.

  10. Disease: H01577 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01577 Essential tremor Essential tremor (ET) is a neurological disorder that is c...hmic, involuntary shaking of one or more parts of the body, and occurs exclusively during voluntary movements (action tremor...) or in positions against gravity (postural tremor). The phenotyp...TLE ... Clinical practice. Essential tremor. ... JOURNAL ... N Engl J Med 345:887-91 (2001) DOI:10.1056/NEJMcp01...A, Rouleau GA ... TITLE ... Exome sequencing identifies FUS mutations as a cause of essential tremor. ... JOURNAL ... Am J Hum Genet 91:313-9 (2012) DOI:10.1016/j.ajhg.2012.07.002 ...

  11. Disease: H00415 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00415 Hepatitis E; Hepatitis E virus (HEV) infection Hepatitis E is an infection with hepatitis...n the range of 0.5% to 4%. Hepatitis E manifests as acute icteric hepatitis in hi...gh-endemicity areas. However, in recent years, cases of hepatitis E have been observed in low-endemicity are...as as well, including chronic hepatitis E with higher mortality rate. Infectious disease ... Hepatitis E viru...cription, env_factor) ... AUTHORS ... Aggarwal R, Naik S ... TITLE ... Epidemiology of hepatitis E: current status

  12. Disease: H00507 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00507 Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DK...CX); Autosomal dominant dyskeratosis congenita (DKCA); Autosomal recessive dyskeratosis congenita (DKCB) Dyskeratosis...gene mutations identified to date share a link to telomere/telomerase biology. Moreover, dyskeratosis congen...HSA:55651] [KO:K11129] (DKCB3) WRAP53 [HSA:55135] (DKCB6) PARN [HSA:5073] [KO:K01148] ... Two variants of dyskeratosis... 613990 615190 616553 224230 613987 613988 616353 PMID:18005359 ... AUTHORS ... Kirwan M, Dokal I ... TITLE ... Dyskeratosis

  13. Disease: H01249 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01249 Ethylmalonic encephalopathy (EE) Ethylmalonic encephalopathy (EE) is an aut...TITLE ... Therapeutic trial in the first three Asian cases of ethylmalonic encephalopathy: response to riboflavin. ... JOURNAL ... J Inherit Metab Dis 24:870-3 (2001) DOI:10.1023/A:1013948409790 ...mer B, Rinaldo P, Hahn SH, Leonard J, Rahman S, Dionisi-Vici C, Garavaglia B, Gasparini P, Zeviani M ... TITLE ... Ethylmalonic encepha...lopathy is caused by mutations in ETHE1, a gene encoding a mitochondrial matrix pro

  14. Disease: H00464 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00464 Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patel...la-short statute syndrome Patella dysplasias are a group of disorders that include aplasia/hypoplasia of patel...lar. Small patella syndrome is a skeletal dysplasia with anomalies of the pelvis. Ossifi...cation of the ischia and inferior pubic rami is also disrupted in patients with small patel...la syndrome. Nail-patella syndrome is a condition caused by mutation in LMX1B that regulates COL4A

  15. Disease: H00849 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available e deficiency; Guanidinoacetate methyltransferase deficiency [DS:H00834]; X-linked creatine deficiency syndrome (XL-CDS) The creatin...e deficiency syndrome is a group of inborn errors of creatine metabolism, that includ...transferase (AGAT) deficiency, and X-linked creatine deficiency syndrome (XL-CDS). Intellectual disability a...nd seizures are common to all three disorders. GAMT deficiency and AGAT deficiency are creatine biosynthesis... disorders and inherited in an autosomal recessive manner. XL-CDS is the creatine

  16. Disease: H00604 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00604 Deafness, autosomal dominant Hereditary deafness is divided into syndromic forms (in which hearing... with 2-3% of the cases of non-syndromic hearing loss. Autosomal-dominant forms of deafness are usually post...-lingual and progressive. Dominant mutations may be consistent with initial function and subsequent hearin...Griffin A, Fernandez B, Lee MK, King MC ... TITLE ... Non-syndromic progressive hearing loss DFNA38 is caused ...2 deficiency impairs otic development and hearing ability in a zebrafish model of

  17. Disease: H00847 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00847 Al-Awadi/Raas-Rothschild syndrome; Ulna and fibula, absence of, with sever ...limb deficiency Al-Awadi/Raas-Rothschild syndrome is a limb malformation disorder that has overlapping pheno...T7A function in Al-Awadi/Raas-Rothschild syndrome whereas impairment is partial i...e A, Pozzolo S ... TITLE ... Limb/pelvis-hypoplasia/aplasia syndrome (Al-Awadi/Raas-Rothschild...ri A, Mari F, Zabel B, Lausch E, Unger S, Superti-Furga A ... TITLE ... Al-Awadi-Raas-Rothschild (limb/pelvis/

  18. Disease: H01712 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01712 Fulminant hepatic failure; Fulminant hepatitis Fulminant hepatic failure (F...e prothrombin time is prolonged by 4-6 seconds or more. While the etiologies of FHF are multiple and varied, viral hepatitis...F from such etiologies as hepatitis A and acetaminophen toxicity are high, whereas those same rates for other types of viral hepatiti...epatic failure (FHF) due to acute hepatitis C. ... JOURNAL ... Pak J Med Sci 31:1009-11 (2015) DOI:10.12669/pjms

  19. Disease: H01686 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01686 Idiopathic portal hypertension; Non-cirrhotic portal fibrosis; Banti's synd...rome Idiopathic portal hypertension (IPH) is a disorder generally classified as a noncirrhotic portal hypertension... of unknown etiology, and is clinically characterized by portal hypertension, splenomegaly, and pancyt...l sclerosis, or Idiopathic noncirrhotic portal hypertension. ICD-10: K76.6 MeSH: ...spects of idiopathic portal hypertension. ... JOURNAL ... Intractable Rare Dis Res 2:94-7 (2013) DOI:10.5582/irdr.2013.v2.3.94 ...

  20. hCGbeta core fragment is a metabolite of hCG: evidence from infusion of recombinant hCG.

    Science.gov (United States)

    Norman, R J; Buchholz, M M; Somogyi, A A; Amato, F

    2000-03-01

    The availability of recombinant human chorionic gonadotrophin (r-hCG) has allowed us to measure its metabolic and renal clearance rates and to study the origin of the beta core fragment of hCG (hCGbetacf). Serum and urine samples were collected from six subjects, after an intravenous injection of 2 mg (equivalent to 44 000 IU Urinary hCG) r-hCG, and assayed for hCG and the beta subunit (hCGbeta). Urine from four of the subjects was also subjected to gel chromatography and assayed for hCGbetacf and hCG. r-hCG, administered as an intravenous dose, was distributed, initially in a volume of 3.4+/-0.7 l (mean+/-s.d.) and then in 6.5+/-1.15 l at steady-state. The disappearance of r-hCG from serum was bi-exponential, with an initial half-life of 4.5+/-0.7 h and a terminal half-life of 29.0+/-4.6 h. The mean residence time was 28. 6+/- 3.6 h and the total systemic clearance rate of r-hCG was 226+/-18 ml/h. The renal clearance rate was 28.75+/-6.2 ml/h (mean+/-s.d). hCGbetacf was detected in all urine samples collected at 6 h intervals. Over the 138 h period of urine collection, 12.9% (range 10.1-17.3% ) of r-hCG injected was recovered as the intact molecule and 1.7% (range 0.8-2.9%) was recovered as the hCGbetacf, in 4 subjects. The molar ratio of hCGbetacf to hCG in urine increased from 3.1+/-1.7%, on day 1, to 76+/-34.3% (mean+/-s.e.m.) on day 5, after r-hCG infusion, suggesting that hCGbetacf is a metabolic product of the infused r-hCG.

  1. Observing shape resonances in ultraslow H^++H elastic scattering

    Science.gov (United States)

    Macek, J. H.; Schultz, D. R.; Ovchinnikov, S. Yu.; Krstic, P. S.

    2004-05-01

    We have calculated highly accurate elastic and charge transfer cross sections for proton-hydrogen scattering at energies 0.0001-10 eV, using fully quantal approach (P.S. Krstic and D.R. Schultz, J. Phys. B 32, 3485 (1999)). A number of resonances are observed. We calculate the positions and widths of the shape resonances in the effective potentials for various orbital angular momenta (J. H. Macek and S. Yu. Ovchinnikov, Phys. Rev. A 50, 468 (1994)). These correlate well with the observed resonances. We acknowledge support from the US DOE through ORNL, managed by UT-Battelle, LLC under contract DE-AC05-00OR22725.

  2. Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer.

    Science.gov (United States)

    Zhang, Mengying; Liu, Hejun; Gao, Yongxiang; Zhu, Zhongliang; Chen, Zijun; Zheng, Peiyi; Xue, Lu; Li, Jixi; Teng, Maikun; Niu, Liwen

    2016-10-04

    Histone chaperones are critical for guiding specific post-transcriptional modifications of histones, safeguarding the histone deposition (or disassociation) of nucleosome (dis)assembly, and regulating chromatin structures to change gene activities. HAT1-interacting factor 1 (Hif1) has been reported to be an H3-H4 chaperone and to be involved in telomeric silencing and nucleosome (dis)assembly. However, the structural basis for the interaction of Hif1 with histones remains unknown. Here, we report the complex structure of Hif1 binding to H2A-H2B for uncovering the chaperone specificities of Hif1 on binding to both the H2A-H2B dimer and the H3-H4 tetramer. Our findings reveal that Hif1 interacts with the H2A-H2B dimer and the H3-H4 tetramer via distinct mechanisms, suggesting that Hif1 is a pivotal scaffold on alternate binding of H2A-H2B and H3-H4. These specificities are conserved features of the Sim3-Hif1-NASP interrupted tetratricopeptide repeat proteins, which provide clues for investigating their potential roles in nucleosome (dis)assembly. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. 1H-NMR urinalysis

    International Nuclear Information System (INIS)

    Yamamoto, Hideaki; Yamaguchi, Shuichi

    1988-01-01

    In an effort to examine the usefulness of 1 H-nuclear magnetic resonance (NMR) urinalysis in the diagnosis of congenital metabolic disorders, 70 kinds of urinary metabolites were analysed in relation to the diagnosis of inborn errors of amino acid and organic acid disorders. Homogated decoupling (HMG) method failed to analyze six metabolites within the undetectable range. When non-decoupling method (NON), in which the materials are dissolved in dimethyl sulfoxide, was used, the identification of signals became possible. The combination of HMG and NON methods was, therefore, considered to identify all of the metabolites. When the urine samples, which were obtained from patients with hyperglycerolemia, hyperornithinemia, glutaric acidemia type II, or glycerol kinase deficiency, were analysed by using both HMG and NON methods, abnormally increased urinary metabolites were detected. 1 H-NMR urinalysis, if used in the combination of HMG and NON methods, may allow simultanenous screening of inborn errors of metabolism of amino acid and organic acid disorders. (Namekawa, K.)

  4. Histone H4 Lysine 20 methylation

    DEFF Research Database (Denmark)

    Jørgensen, Stine; Schotta, Gunnar; Sørensen, Claus Storgaard

    2013-01-01

    of histones have emerged as key regulators of genomic integrity. Intense research during the past few years has revealed histone H4 lysine 20 methylation (H4K20me) as critically important for the biological processes that ensure genome integrity, such as DNA damage repair, DNA replication and chromatin...... compaction. The distinct H4K20 methylation states are mediated by SET8/PR-Set7 that catalyses monomethylation of H4K20, whereas SUV4-20H1 and SUV4-20H2 enzymes mediate further H4K20 methylation to H4K20me2 and H4K20me3. Disruption of these H4K20-specific histone methyltransferases leads to genomic...

  5. pH sensor calibration procedure

    OpenAIRE

    Artero Delgado, Carola; Nogueras Cervera, Marc; Manuel Lázaro, Antonio; Prat Tasias, Jordi; Prat Farran, Joana d'Arc

    2013-01-01

    This paper describes the calibration of pH sensor located at the OBSEA marine Observatory. This instrument is based on an industrial pH electrode that is connected to a CTD instrument (Conductivity, Temperature, and Depth ). The calibration of the pH sensor has been done using a high precision spectrophotometer pH meter from Institute of Marine Sciences (ICM), and in this way it has been obtained a numerical function for the p H sensor propor...

  6. Homotopy Algorithm for Fixed Order Mixed H2/H(infinity) Design

    Science.gov (United States)

    Whorton, Mark; Buschek, Harald; Calise, Anthony J.

    1996-01-01

    Recent developments in the field of robust multivariable control have merged the theories of H-infinity and H-2 control. This mixed H-2/H-infinity compensator formulation allows design for nominal performance by H-2 norm minimization while guaranteeing robust stability to unstructured uncertainties by constraining the H-infinity norm. A key difficulty associated with mixed H-2/H-infinity compensation is compensator synthesis. A homotopy algorithm is presented for synthesis of fixed order mixed H-2/H-infinity compensators. Numerical results are presented for a four disk flexible structure to evaluate the efficiency of the algorithm.

  7. Disease: H01611 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01611 Alcohol dependence Alcohol dependence (AD) is a chronic but often disease t...ol even when it causes problems, having to drink more to get the same effect (physical dependence), or havin...l M, Pirmohamed M ... TITLE ... Pharmacotherapy for alcohol dependence: A stratified approach. ... JOURNAL ... Pha...iec J, Samochowiec A, Puls I, Bienkowski P, Schott BH ... TITLE ... Genetics of alcohol dependence...g C, Wang F, Zhang XY, Vanderlinden LA, Tabakoff B, Luo X ... TITLE ... Genome-wide association discoveries of alcohol dependence. ... JOURNAL ... Am J Addict 23:526-39 (2014) DOI:10.1111/j.1521-0391.2014.12147.x ... PMID:23170934 (gene) ... AUTHORS ... Rietschel M, Treutlein J ... TITLE ... The genetics of alcohol dependence. ... JOURNAL ... Ann N Y Acad Sci 1282:39-70 (2013) DOI:10.1111/j.1749-6632.2012.06794.x ...

  8. Disease: H00499 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00499 Spondylocarpotarsal synostosis syndrome Spondylocarpotarsal synostosis syndrome is an autosomal recessive disease characterized by the malsegmentation of vertebrae and the fusion of carpal and tarsal bones. Retinal anomalies and hearing loss are also observed. Spondylocarpotarsal synostosis syndrome is due to FLNB mutations. Skeletal dysplasia FLNB (nonsense mutation) [HSA:2317] [KO:K04437] ... MeSH: C535780 OMIM: 272460 PMID:18386804 (description, gene) ... AUTHORS ... Brunetti-Pierri N, Esposito V, De Brasi D, Mattiacci DM, Krakow D, Lee B, Salerno M ... TITLE ... Spondylocarpotarsal synostosis: long-term follow-up of a case due to FLNB mutations. ... JOURNAL ... Am J Med Genet A 146A:1230-3 (2008) DOI:10.1002/ajmg.a.32303 ...

  9. Alkaline pH sensor molecules.

    Science.gov (United States)

    Murayama, Takashi; Maruyama, Ichiro N

    2015-11-01

    Animals can survive only within a narrow pH range. This requires continual monitoring of environmental and body-fluid pH. Although a variety of acidic pH sensor molecules have been reported, alkaline pH sensor function is not well understood. This Review describes neuronal alkaline pH sensors, grouped according to whether they monitor extracellular or intracellular alkaline pH. Extracellular sensors include the receptor-type guanylyl cyclase, the insulin receptor-related receptor, ligand-gated Cl- channels, connexin hemichannels, two-pore-domain K+ channels, and transient receptor potential (TRP) channels. Intracellular sensors include TRP channels and gap junction channels. Identification of molecular mechanisms underlying alkaline pH sensing is crucial for understanding how animals respond to environmental alkaline pH and how body-fluid pH is maintained within a narrow range. © 2015 Wiley Periodicals, Inc.

  10. Uses of monoclonal antibody 8H9

    Science.gov (United States)

    Cheung, Nai-Kong V.

    2013-04-09

    This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides different uses of the monoclonal antibody 8H9 or its derivative.

  11. H(2s) excitation in 10-100 keV H+ - H collisions

    International Nuclear Information System (INIS)

    Higgins, D.P.; Geddes, J.; Gilbody, H.B.

    1996-01-01

    The authors have used a crossed beam technique to determine cross sections for 2s excitation of H atoms in 10-100 keV collisions. The results extend their previous 4-26 keV measurements to intermediate energies where theoretical predictions based on close coupling methods are known to be strongly dependent on the choice of the expansion basis. The 4-100 keV cross sections exhibit an undulatory structure similar to that predicted by some of the many close coupling calculations but good quantitative agreement is shown to be very limited. Close coupling calculations which employ large basis sets at the expense of target states are shown to agree less satisfactorily with experiment than those which include only the dominant 1s capture channel

  12. Differential cross sections for transfer into the 2S state of hydrogen: H+ + H2, H+ + D2

    International Nuclear Information System (INIS)

    Williams, D.G.; Lee, A.R.; Butcher, E.C.

    1986-01-01

    Differential cross sections for electron capture into the 2S state of hydrogen are presented for the reactions H + + H 2 and H + + D 2 . The results are for laboratory collision energies between 3.3 and 24 keV and scattering angles between 30 and 90'. The measurements expand on the results previously presented. (author)

  13. DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition

    Energy Technology Data Exchange (ETDEWEB)

    Elsässer, Simon J; Huang, Hongda; Lewis, Peter W; Chin, Jason W; Allis, C David; Patel, Dinshaw J [MSKCC; (Rockefeller); (MRC)

    2013-01-24

    Histone chaperones represent a structurally and functionally diverse family of histone-binding proteins that prevent promiscuous interactions of histones before their assembly into chromatin. DAXX is a metazoan histone chaperone specific to the evolutionarily conserved histone variant H3.3. Here we report the crystal structures of the DAXX histone-binding domain with a histone H3.3–H4 dimer, including mutants within DAXX and H3.3, together with in vitro and in vivo functional studies that elucidate the principles underlying H3.3 recognition specificity. Occupying 40% of the histone surface-accessible area, DAXX wraps around the H3.3–H4 dimer, with complex formation accompanied by structural transitions in the H3.3–H4 histone fold. DAXX uses an extended α-helical conformation to compete with major inter-histone, DNA and ASF1 interaction sites. Our structural studies identify recognition elements that read out H3.3-specific residues, and functional studies address the contributions of Gly90 in H3.3 and Glu225 in DAXX to chaperone-mediated H3.3 variant recognition specificity.

  14. An ENDOR spectrum of H atoms in solid H{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Kumada, Takayuki; Kumagai, J.; Aratono, Yasuyuki; Miyazaki, T. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kitagawa, N.; Noda, T.

    1998-10-01

    An ENDOR spectrum of H atoms produced in the {gamma}-rays irradiated solid H{sub 2} was measured at 4.2 K in order to elucidate the structures of the local environment of the H atoms in solid H{sub 2}. We found that the H atoms were not trapped in interstitial sites but in substitutional sites of the solid, and almost all ortho-H{sub 2} molecules at the first nearest sites from the H atoms converted into para-H{sub 2} molecules. This result shows that the ortho-para conversion is induced by electron spins of the H atoms. (author)

  15. Electronic structure of homoleptic transition metal hydrides: TiH4, VH4, CrH4, MnH4, FeH4, CoH4, and NiH4

    International Nuclear Information System (INIS)

    Hood, D.M.; Pitzer, R.M.; Schaefer III, H.F.

    1979-01-01

    Ab initio molecular electronic structure theory has been applied to the family of transition metal tetrahydrides TiH 4 through NiH 4 . For the TiH 4 molecule a wide range of contracted Gaussian basis sets has been tested at the self-consistent-field (SCF) level of theory. The largest basis, labeled M(14s 11p 6d/10s 8p 3d), H(5s 1p/3s 1p), was used for all members of the series and should yield wave functions approaching true Hartree-Fock quality. Predicted SCF dissociation energies (relative to M+4H) and M--H bond distances are TiH 4 132 kcal, 1.70 A; VH 4 86 kcal, 1.64 A; CrH 4 65 kcal, 1.59 A; MnH 4 -- 36 kcal, 1.58 A; FeH 4 0 kcal, 1.58 A; CoH 4 27 kcal, 1.61 A; and NiH 4 18 kcal, 1.75 A. It should be noted immediately that each of these SCF dissociation energies will be increased by electron correlation effects by perhaps as much as 90 kcal. For all of these molecules except TiH 4 excited states have also been studied. One of the most interesting trends seen for these excited states is the shortening of the M--H bond as electrons are transferred from the antibonding 4t 2 orbital to the nonbonding 1e orbitals

  16. Adult 4-H Volunteer Empowerment in 4-H Youth Development Settings

    Science.gov (United States)

    Olsen, Pamela

    2009-01-01

    The primary purpose of this study was to determine which factors related to adult 4-H volunteer empowerment in 4-H youth development settings. This study examined the relationship of adult 4-H volunteers' perceived leadership styles of Oregon 4-H Youth Development Educators (YDE) to the adult 4-H volunteer sense of empowerment. In addition,…

  17. Homologous histamine H1 receptor desensitization results in reduction of H1 receptor agonist efficacy

    NARCIS (Netherlands)

    Leurs, R; Smit, M J; Bast, A; Timmerman, H

    1991-01-01

    Prolonged exposure of the guinea-pig intestinal longitudinal smooth muscle to histamine caused homologous desensitization of the H1 receptor, which led to reduced H1 receptor-mediated production of [3H]inositol phosphates as well as to reduced H1 agonist-induced contractions. [3H]Mepyramine binding

  18. S and H Cycle Engine

    International Nuclear Information System (INIS)

    Strobl, William C.; Holland, Joe P.

    2002-01-01

    Our thirst for energy is increasing at an astounding rate. World population growth is estimated to increase by 40% (to 8.5 billion) by 2050, with annual electrical energy usage estimated increase by 100% (to 25 terawatt-hours). We must find new means and fuels as well as significantly improve the efficiency of current power plants to accommodate this growing electrical energy demand. This demand is also growing in the field of space flight. Present energy and propulsion systems are limited in the amount of power (energy) that can be generated by today's technology. This limits the distance that can be safely traveled by manned and un-manned space systems. Space flight is primarily governed by two factors: time and energy. Increasing energy of space propulsion systems will decrease flight time or allow reaching farther out into space safely for manned exploration of our solar system. For example, a round trip manned mission to Mars would take about 400 days with a NERVA type thermal nuclear rocket. To reduce the 400 days to 80 days would require an increase of energy by a factor of five. We need to develop space propulsion systems with much greater energy capability than we have today to satisfy the expansion of space exploration. The S and H Cycle nuclear engine provides a revolutionary technological approach that can contribute significantly toward solving the World electrical energy and the space travel energy requirements. (authors)

  19. Disease: H00682 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00682 Woodhouse-Sakati syndrome; Hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome Woodhouse-Sakati syndrome (WSS) is a rare autosomal recessive disorder that encompasses alopecia, hypogonadism, diabetes mellitus, mental retardation, and extrapyramidal signs. Additional manifestations include sensorineural hearing loss, seizures, T-wave abnormalities on ECG, and polyneuropathy. The syndrome is caused by mutation of the C2orf37 gene encoding a nucleolar protein. Congenital disorder C2orf37 [HSA:80067] ... MeSH: C536742 OMIM: 241080 PMID:17710875 (description) ... AUTHORS ... Medica I, Sepcic J, Peterlin B ... TITLE ... Woodhouse-Sakati syndrome: case report and symptoms review. ... JOURNAL ... Genet Couns 18:227-31 (2007) ... PMID:20507343 (gene) ... AUTHORS ... Alazami AM, Schneider SA, Bonneau D, Pasquier L, Carecchio M, Kojovic M, Steindl K, de Kerdanet M, Nezarati MM, Bhatia KP, Degos B, Goh E, Alkuraya FS ... TITLE ... C2orf37 mutational spectrum in Woodhouse-Sakati syndrome patients. ... JOURNAL ... Clin Genet 78:585-90 (2010) DOI:10.1111/j.1399-0004.2010.01441.x ...

  20. Fetal scalp pH testing

    Science.gov (United States)

    Fetal scalp blood; Scalp pH testing; Fetal blood testing - scalp; Fetal distress - fetal scalp testing; Labor - fetal scalp testing ... a baby. In these cases, testing the scalp pH can help the doctor decide whether the fetus ...

  1. Neutron scattering studies of the H2a-H2b and (H3-H4)/sub 2/ histone complexes

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, R.D.

    1982-01-01

    Neutron scattering experiments have shown that both the (H3-H4)/sub 2/ and H2a-H2b histone complexes are quite asymmetric in solution. The (H3-H4)/sub 2/ tetramer is an oblate or flattened structure, with a radius of gyration almost as large as that of the core octamer. If the tetramer is primarily globular, it must have an axial ratio of about 1:5. It is more likely, however, that this asymmetry results in part from N-terminal arms that extend outward approximately within the major plane of the particle. If this is the case, less asymmetric models for the globular part of the tetramer, including a dislocated disk, can be made consistent with the scattering data. The H2a-H2b dimer, on the other hand, is an elongated structure. 48 references, 12 figures, 1 table.

  2. Neutron scattering studies of the H2a-H2b and (H3-H4)2 histone complexes

    International Nuclear Information System (INIS)

    Carlson, R.D.

    1982-01-01

    Neutron scattering experiments have shown that both the (H3-H4) 2 and H2a-H2b histone complexes are quite asymmetric in solution. The (H3-H4) 2 tetramer is an oblate or flattened structure, with a radius of gyration almost as large as that of the core octamer. If the tetramer is primarily globular, it must have an axial ratio of about 1:5. It is more likely, however, that this asymmetry results in part from N-terminal arms that extend outward approximately within the major plane of the particle. If this is the case, less asymmetric models for the globular part of the tetramer, including a dislocated disk, can be made consistent with the scattering data. The H2a-H2b dimer, on the other hand, is an elongated structure. 48 references, 12 figures, 1 table

  3. Acid loading test (pH)

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003615.htm Acid loading test (pH) To use the sharing features on this page, please enable JavaScript. The acid loading test (pH) measures the ability of the ...

  4. Search for 4H, 5H and 6H nuclei in the 11B-induced reaction on 9Be

    International Nuclear Information System (INIS)

    Belozerov, A.V.; Borcea, C.; Dlouhy, Z.

    1985-01-01

    In the 11 B(88.0 MeV)+ 9 Be reaction the energy spectra of the 14 O, 15 O and 16 O nuclei have been measured to obtain some information about their partners in the exit channel - the neutron-rich hydrogen isotopes 4 H, 5 H and 6 H. The unbound levels in the 4 H and 6 H systems have been observed at excitation energies of 3.5 +- 0.5 MeV (GITA approximately 1 MeV) and 2.6 +- 0.5 MeV (GITA=1.5 +- 0.3 MeV), respectively

  5. Avian Influenza A (H5N1)

    Centers for Disease Control (CDC) Podcasts

    In this podcast, CDC's Dr. Tim Uyeki discusses H5N1, a subtype of influenza A virus. This highly pathogenic H5N1 virus doesn't usually infect people, although some rare infections with H5N1 viruses have occurred in humans. We need to use a comprehensive strategy to prevent the spread of H5N1 virus among birds, including having human health and animal health work closely together.

  6. Interconversion of η3-H2SiRR' σ-complexes and 16-electron silylene complexes via reversible H-H or C-H elimination.

    Science.gov (United States)

    Lipke, Mark C; Neumeyer, Felix; Tilley, T Don

    2014-04-23

    Solid samples of η(3)-silane complexes [PhBP(Ph)3]RuH(η(3)-H2SiRR') (R,R' = Et2, 1a; PhMe, 1b; Ph2, 1c, MeMes, 1d) decompose when exposed to dynamic vacuum. Gas-phase H2/D2 exchange between isolated, solid samples of 1c-d3 and 1c indicate that a reversible elimination of H2 is the first step in the irreversible decomposition. An efficient solution-phase trap for hydrogen, the 16-electron ruthenium benzyl complex [PhBP(Ph)3]Ru[η(3)-CH2(3,5-Me2C6H3)] (3) reacts quantitatively with H2 in benzene via elimination of mesitylene to form the η(5)-cyclohexadienyl complex [PhBP(Ph)3]Ru(η(5)-C6H7) (4). This H2 trapping reaction was utilized to drive forward and quantify the elimination of H2 from 1b,d in solution, which resulted in the decomposition of 1b,d to form 4 and several organosilicon products that could not be identified. Reaction of {[PhBP(Ph)3]Ru(μ-Cl)}2 (2) with (THF)2Li(SiHMes2) forms a new η(3)-H2Si species [PhBP(Ph)3]Ru[CH2(2-(η(3)-H2SiMes)-3,5-Me2C6H2)] (5) which reacts with H2 to form the η(3)-H2SiMes2 complex [PhBP(Ph)3]RuH(η(3)-H2SiMes2) (1e). Complex 1e was identified by NMR spectroscopy prior to its decomposition by elimination of Mes2SiH2 to form 4. DFT calculations indicate that an isomer of 5, the 16-electron silylene complex [PhBP(Ph)3]Ru(μ-H)(═SiMes2), is only 2 kcal/mol higher in energy than 5. Treatment of 5 with XylNC (Xyl = 2,6-dimethylphenyl) resulted in trapping of [PhBP(Ph)3]Ru(μ-H)(═SiMes2) to form the 18-electron silylene complex [PhBP(Ph)3]Ru(CNXyl)(μ-H)(═SiMes2) (6). A closely related germylene complex [PhBP(Ph)3]Ru[CN(2,6-diphenyl-4-MeC6H2)](H)(═GeH(t)Bu) (8) was prepared from reaction of (t)BuGeH3 with the benzyl complex [PhBP(Ph)3]Ru[CN(2,6-diphenyl-4-MeC6H2)][η(1)-CH2(3,5-Me2C6H3)] (7). Single crystal XRD analysis indicated that unlike for 6, the hydride ligand in 8 is a terminal hydride that does not engage in 3c-2e Ru-H → Ge bonding. Complex 1b is an effective precatalyst for the catalytic Ge-H dehydrocoupling

  7. Characterization of the UV-crosslinked heterodimer of histones H2B and H4

    International Nuclear Information System (INIS)

    Johnson, E.R.; Brown, D.M.; DeLange, R.J.

    1986-01-01

    At relatively high salt concentrations (1.2 M), histone 2B (H2B) and histone 4 (H4) can be covalently crosslinked by irradiation with ultraviolet light to yield a mixture of the three possible dimers: H2B-H2B, H4-H4, and H2B-H4. The formation of the H2B-H4 heterodimer was found to be favored at lower histone concentrations (> 90% H2B-H4 at 0.1 mg/ml total histone protein). CNBr cleavage of the H2B-H4 dimer produced three fragments which were separated by reverse phase HPLC. These fragments were identified by amino acid compositional analysis to be H4(85-102), H2B(62-125), and the crosslinked N-terminal regions H2B(1-59)-H4(1-84). Amino acid sequence analysis of the crosslinked fragment indicated that tyrosine-40 of H2B is likely involved in the covalent crosslinkage which joins the histone monomers to form the heterodimer

  8. Anti-H-Y responses of H-2b mutant mice.

    Science.gov (United States)

    Simpson, E; Gordon, R D; Chandler, P R; Bailey, D

    1978-10-01

    Two strains of H-2b mutant mice, H-2ba and H-2bf, in which the mutational event took place at H-2K, make anti-H-Y cytotoxic T cell responses which are H-2-restricted, Db-associated and indistinguishable in target cell specificity from those of H-2b mice. Thus, alteration of the H-2K molecule affects neither the Ir gene controlling the response, nor the associative antigen. On the other hand, one H-2Db mutant strain, H-2bo, although it makes a good anti-H-Y cytotoxic response, shows target cell specificity restricted to its own Dbo antigen(s), and neither H-2b, H-2ba or H-2bf anti-H-Y cytotoxic cells kill H-2bo male target cells. Thus, the alteration of the H-2Db molecule does not affect the Ir gene of H-2b mice, but it does alter the H-2Db-associative antigen.

  9. Effects of H-H interactions on the heat of H absorption by β and delta Zr hydrides

    International Nuclear Information System (INIS)

    Ohta, Yutaka; Mabuchi, Mahito; Naito, Shizuo; Hashino, Tomoyasu

    1987-01-01

    The heat of H absorption by β and delta Zr hydrides has been measured by isoperibol calorimetry over the range of H concentration 0.1 - 1.6 H/Zr at temperatures 873-1273 K. In the β hydride the heat per H atom (differential heat) increases and then decreases as the H concentration increases. In the delta hydride only a decrease at large H concentrations is clearly observed. The increase in the β hydride is related by self-consistent calculations to a pair indirect interaction between H atoms; the decreases in the β and delta hydrides are due to a pair direct interaction which is of the form of a screened Coulomb potential. The differential heat is estimated from the pair indirect and direct interactions by the use of Monte Carlo simulations and compared with the measured differential heat. (author)

  10. Arthur H. Compton and Compton Scattering

    Science.gov (United States)

    dropdown arrow Site Map A-Z Index Menu Synopsis Arthur H. Compton and Compton Scattering Resources with Additional Information * Compton Honored * Compton Scattering Arthur H. Compton Courtesy of Lawrence Berkeley , 1923 Establishing Site X: Letter, Arthur H. Compton to Enrico Fermi, September 14, 1942, DOE Technical

  11. 21 CFR 189.220 - Flectol H.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Flectol H. 189.220 Section 189.220 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... Addition to Human Food Through Food-Contact Surfaces § 189.220 Flectol H. (a) Flectol H is the chemical 1,2...

  12. H.264/AVC Video Compression on Smartphones

    Science.gov (United States)

    Sharabayko, M. P.; Markov, N. G.

    2017-01-01

    In this paper, we studied the usage of H.264/AVC video compression tools by the flagship smartphones. The results show that only a subset of tools is used, meaning that there is still a potential to achieve higher compression efficiency within the H.264/AVC standard, but the most advanced smartphones are already reaching the compression efficiency limit of H.264/AVC.

  13. H1N1 influenza (Swine flu)

    Science.gov (United States)

    Swine flu; H1N1 type A influenza ... The H1N1 virus is now considered a regular flu virus. It is one of the three viruses included in the regular (seasonal) flu vaccine . You cannot get H1N1 flu virus from ...

  14. Strengthening 4-H by Analyzing Enrollment Data

    Science.gov (United States)

    Hamilton, Stephen F.; Northern, Angela; Neff, Robert

    2014-01-01

    The study reported here used data from the ACCESS 4-H Enrollment System to gain insight into strengthening New York State's 4-H programming. Member enrollment lists from 2009 to 2012 were analyzed using Microsoft Excel to determine trends and dropout rates. The descriptive data indicate declining 4-H enrollment in recent years and peak enrollment…

  15. The H II regions of IC 1613

    International Nuclear Information System (INIS)

    Hodge, P.; Lee, M.G.; Gurwell, M.

    1990-01-01

    Narrow-band CCD H-alpha imaging of the Local Group irregular galaxy IC 1613 has revealed a total of 77 H II regions, five of which are complexes of several smaller emission regions. Positions, H-alpha luminosities, and sizes of these objects are tabulated. The H-alpha luminosity function has the same shape as that for more luminous galaxies, following a power law with an exponent of -1.6. The faintest H II regions are at the low-luminosity end of the generally observed luminosity function for H II regions in galaxies, with fluxes of only 10 to the 35th erg/sec. The size distribution has an exponential shape, as for other galaxies, with a size scale of 56 pc. The morphologies of different H II regions are discussed and compared to those in other galaxies. Published radio continuum maps compare well with the H-alpha emission distribution. The distribution of H I is also similar in the central areas to the H II with, however, a tendency for the H II regions to lie to one side of H I peaks. 31 refs

  16. Disease: H00238 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00238 Fanconi anemia Fanconi anemia (FA), a recessive syndrome with both autosomal and X-linked inheritance, features diverse clinical symptoms, such as progressive bone marrow failures, chromosomal instability and susceptibility to cancer. To date, 13 FA gene products have been identified, which cooperate in a common DNA damage-activated signaling pathway regulating DNA repair (the FA pathway). Hematologic disease FANCA [HSA:2175] [KO:K10888] FANCB [HSA:2187] [KO:K10889] FANCC [HSA:2176] [KO:K10890] BRCA2 [HSA:675] [KO:K08775] FANCD2 [HSA:2177] [KO:K10891] FANCE [HSA:2178] [KO:K10892] FANCF [HSA:2188] [KO:K10893] FANCG [HSA:2189] [KO:K10894] FANCI [HSA:55215] [KO:K10895] BRIP1 [HSA:83990] [KO:K15362] FANCL [HSA:55120] [KO:K10606] FANCM [HSA:57697] [KO:K10896] FANCN [HSA:79728] [KO:K10897] RAD51C [HSA:5889] [KO:K10870] RAD51 [HSA:5888] [KO:K04482] XRCC2 [HSA:7516] [KO:K10879] MAD2L2 [HSA:10459] [KO:K13728] ... ICD-10: D61.0 OMIM: 227650 300514 227645 605724 227646 600901 603467 609053 609054 608111 609644 610832 614082 613390 617244 617247 617243 PMID:18995829 ... AUTHORS ... Cohn MA, D'Andrea AD ... TITLE ... Chromatin recruitment of DNA repair p...roteins: lessons from the fanconi anemia...D, D'Andrea AD, Soulier J ... TITLE ... Biallelic inactivation of REV7 is associated with Fanconi anemia... ... TITLE ... The Fanconi anemia...Kolling FW 4th, Howlett NG

  17. The synthesis of [fluorophenyl-3H(N)] ocfentanil and [fluorophenyl-3H(N)] brifentanil

    International Nuclear Information System (INIS)

    Filer, C.N.; Nugent, R.P.

    1995-01-01

    [Fluorophenyl- 3 H(N)] Ocfentanil and [fluorophenyl- 3 H(N)] brifentanil were synthesized by catalytic tritiation of appropriate bromo precursors. The products were purified by preparative HPLC and characterized chromatographically and by proton decoupled 3 H NMR. (author)

  18. Histones H10a and H10b are the same as CHO histones H1(III) and H1(IV):new features of H10 phosphorylation during the cell cycle

    International Nuclear Information System (INIS)

    D'Anna, J.A.; Gurley, L.R.; Becker, R.R.

    1981-01-01

    Two histone H1 fractions [H1(I) and H1(II) and two histone H1 0 fractions (H1 0 a and H1 0 b) have been isolated from butyrate-treated Chinese hamster (line CHO) cells by guanidine hydrochloride gradient chromatography on Bio-Rex 70 ion-exchange resin. The fractions have been identified by electrophoresis and amino acid analyses. Electrophoretic analysis of cyanogen bromide treated H1 0 in long acid-urea-polyacrylamide gels suggests that H1 0 a and H1 0 b differ, at least, within the 20-30 residue fragment(s) removed by the cyanogen bromide clevage. Shallow-gradient Bio-Rex 70 chromatography indicates that histones H1 0 a and H1 0 b are the same as the respective CHO histones, H1(III) and H1(IV). This identification and the phosphate incorporation data of Gurley et al. (1975) reveal new features about H1 0 phosphorylation: (1) following release from G 1 arrest, H1 0 a and H1 0 b become phosphorylated in late G 1 prior to DNA synthesis; (2) H1 0 a and H1 0 b are phosphorylated at similar rates throughout the cell cycle. These and other data demonstrate that histone H1 0 is phosphorylated in a cell cycle dependent fashion which mimics that of histone H1

  19. Efficient ionizer for polarized H- formation

    International Nuclear Information System (INIS)

    Alessi, J.G.

    1985-01-01

    An ionizer is under development for a polarized H - source based on the resonant charge exchange reaction polarized H 0 + D - → polarized H - + D 0 . The polarized H 0 beam passes through the center of a magnetron surface-plasma source having an annular geometry, where it crosses a high current (approx.0.5 A), 200 eV D - beam. Calculations predict an H 0 → H - ionization efficiency of approx.7%, more than an order of magnitude higher than that obtained on present ground state atomic beam sources. In initial experiments using an unpolarized H 0 beam, H - currents in excess of 100 μA have been measured. While the ionization efficiency is now only about the same as other methods (Cs beam, for example), the results are encouraging since it appears that by injecting positive ions to improve the space-charge neutralization, and by improving the extraction optics, considerable gains in intensity will be made. We will then use this ionizer with a polarized H 0 beam, and measure the polarization of the resulting H - beam. If no depolarization is observed this ionizer will be combined with an atomic beam, cooled to 5 to 6 K, to give a polarized H - beam expected to be in the milliampere range for use in the AGS

  20. Polarized H- source development at BNL

    International Nuclear Information System (INIS)

    Alessi, J.G.; Hershcovitch, A.; Kponou, A.; Niinikoski, T.; Sluyters, T.

    1986-01-01

    The AGS polarized H - source (PONI-1) now produces currents of 25-40 μA, and has operated reliably during polarized physics runs. A new polarized source, having as its goal mA's of H-vector, is now under development. An atomic hydrogen beam has been cooled to about 20 K with a forward flux of approx.10 19 atoms/s/sr. A superconducting solenoid having a calculated acceptance angle of 0.1 sr for the cold H 0 beam, is now being built. An ionizer for the resulting polarized H 0 beam based on resonant charge exchange of H 0 with D - , is being tested. 500 μA of H - have been produced by ionizing an unpolarized H 0 beam using this ionizer

  1. [H reflex in patients with spastic quadriplegia].

    Science.gov (United States)

    Miyama, Sahoko; Arimoto, Kiyoshi; Kimiya, Satoshi

    2009-01-01

    Hoffmann reflex (H reflex) is an electrically elicited spinal monosynaptic reflex. H reflex was examined in 18 patients with spastic quadriplegia who had perinatal or postnatal problems. H reflex was elicitable in 11 patients for the abductor pollicis brevis (61.1%), 10 for the abductor digiti minimi (55.6%) and 16 for the abductor hallucis (88.9%). Because the abductor pollicis brevis and the abductor digiti minimi do not exhibit H reflex in normal subjects, it was suggested that the excitability of alpha motor neurons innervating these muscles was increased. H reflex was not detected for the extensor digitorum brevis in any patients, indicating the difference in the excitability among alpha motor neurons. In some patients, H reflex did not disappear under supramaximal stimuli. We conclude that the mechanism of evolution of H reflex in patients with spastic quadriplegia is different from that in normal subjects.

  2. Palladium Catalyzed Allylic C-H Alkylation

    DEFF Research Database (Denmark)

    Engelin, Casper Junker; Fristrup, Peter

    2011-01-01

    are highlighted with emphasis on those leading to C-C bond formation, but where it was deemed necessary for the general understanding of the process closely related C-H oxidations and aminations are also included. It is found that C-H cleavage is most likely achieved by ligand participation which could involve......-H alkylation reaction which is the topic of the current review. Particular emphasis is put on current mechanistic proposals for the three reaction types comprising the overall transformation: C-H activation, nucleophillic addition, and re-oxidation of the active catalyst. Recent advances in C-H bond activation...... an acetate ion coordinated to Pd. Several of the reported systems rely on benzoquinone for re-oxidation of the active catalyst. The scope for nucleophilic addition in allylic C-H alkylation is currently limited, due to demands on pKa of the nucleophile. This limitation could be due to the pH dependence...

  3. Flat H Frangible Joint Evolution

    Science.gov (United States)

    Diegelman, Thomas E.; Hinkel, Todd J.; Benjamin, Andrew; Rochon, Brian V.; Brown, Christopher W.

    2016-01-01

    Space vehicle staging and separation events require pyrotechnic devices. They are single-use mechanisms that cannot be tested, nor can failure-tolerant performance be demonstrated in actual flight articles prior to flight use. This necessitates the implementation of a robust design and test approach coupled with a fully redundant, failure-tolerant explosive mechanism to ensure that the system functions even in the event of a single failure. Historically, NASA has followed the single failure-tolerant (SFT) design philosophy for all human-rated spacecraft, including the Space Shuttle Program. Following the end of this program, aerospace companies proposed building the next generation human-rated vehicles with off-the-shelf, non-redundant, zero-failure-tolerant (ZFT) separation systems. Currently, spacecraft and launch vehicle providers for both the Orion and Commercial Crew Programs (CCPs) plan to deviate from the heritage safety approach and NASA's SFT human rating requirements. Both programs' partners have base-lined ZFT frangible joints for vehicle staging and fairing separation. These joints are commercially available from pyrotechnic vendors. Non-human-rated missions have flown them numerous times. The joints are relatively easy to integrate structurally within the spacecraft. In addition, the separation event is debris free, and the resultant pyro shock is lower than that of other design solutions. It is, however, a serious deficiency to lack failure tolerance. When used for critical applications on human-rated vehicles, a single failure could potentially lead to loss of crew (LOC) or loss of mission (LOM)). The Engineering and Safety & Mission Assurance directorates within the NASA Johnson Space Center took action to address this safety issue by initiating a project to develop a fully redundant, SFT frangible joint design, known as the Flat H. Critical to the ability to retrofit on launch vehicles being developed, the SFT mechanisms must fit within the same

  4. Speciation in the aqueous H+/H2VO4-/H2O2/citrate system of biomedical interest.

    Science.gov (United States)

    Gorzsás, András; Getty, Kendra; Andersson, Ingegärd; Pettersson, Lage

    2004-09-21

    The speciation in the quaternary aqueous H+/H2VO4-/H2O2/citrate (Cit3-) and H+/H2VO4-/Cit3-/L-(+)-lactate (Lac-) systems has been determined at 25 degrees C in the physiological medium of 0.150 M Na(Cl). A combination of 51V NMR integral intensities and chemical shift (Bruker AMX500) as well as potentiometric data (glass electrode) have been collected and evaluated with the computer program LAKE, which is able to treat multimethod data simultaneously. The pKa-values for citric acid have been determined as 2.94, 4.34 and 5.61. Altogether six vanadate-citrate species have been found in the ternary H+/H2VO4-/Cit3- system in the pH region 2-10, only two of which are mononuclear. Reduction of vanadium(V) becomes more pronounced at pH acidic solutions limited the final model to pH > 4. In the quaternary H+/H2VO4-/Cit3-/Lac- system, two mixed-ligand species have been determined, with the compositions V2CitLac2- and V2CitLac3- (pKa = 5.0). To our knowledge, this is the first time such complexes have been reported for vanadium(V). 51V NMR chemical shifts, compositions and formation constants are given, and equilibrium conditions are illustrated in distribution diagrams as well as the fit of the model to the experimental data. When suitable, structural proposals are given, based on 13C NMR measurements and available literature data of related compounds.

  5. Defense In-Depth Accident Analysis Evaluation of Tritium Facility Bldgs. 232-H, 233-H, and 234-H

    International Nuclear Information System (INIS)

    Blanchard, A.

    1999-01-01

    'The primary purpose of this report is to document a Defense-in-Depth (DID) accident analysis evaluation for Department of Energy (DOE) Savannah River Site (SRS) Tritium Facility Buildings 232-H, 233-H, and 234-H. The purpose of a DID evaluation is to provide a more realistic view of facility radiological risks to the offsite public than the bounding deterministic analysis documented in the Safety Analysis Report, which credits only Safety Class items in the offsite dose evaluation.'

  6. Comparative evaluation of H&H and WFNS grading scales with modified H&H (sans systemic disease): A study on 1000 patients with subarachnoid hemorrhage.

    Science.gov (United States)

    Aggarwal, Ashish; Dhandapani, Sivashanmugam; Praneeth, Kokkula; Sodhi, Harsimrat Bir Singh; Pal, Sudhir Singh; Gaudihalli, Sachin; Khandelwal, N; Mukherjee, Kanchan K; Tewari, M K; Gupta, Sunil Kumar; Mathuriya, S N

    2018-01-01

    The comparative studies on grading in subarachnoid hemorrhage (SAH) had several limitations such as the unclear grading of Glasgow Coma Scale 15 with neurological deficits in World Federation of Neurosurgical Societies (WFNS), and the inclusion of systemic disease in Hunt and Hess (H&H) scales. Their differential incremental impacts and optimum cut-off values for unfavourable outcome are unsettled. This is a prospective comparison of prognostic impacts of grading schemes to address these issues. SAH patients were assessed using WFNS, H&H (including systemic disease), modified H&H (sans systemic disease) and followed up with Glasgow Outcome Score (GOS) at 3 months. Their performance characteristics were analysed as incremental ordinal variables and different grading scale dichotomies using rank-order correlation, sensitivity, specificity, positive predictive value, negative predictive value, Youden's J and multivariate analyses. A total of 1016 patients were studied. As univariate incremental variable, H&H sans systemic disease had the best negative rank-order correlation coefficient (-0.453) with respect to lower GOS (p H&H sans systemic disease had the greatest adjusted incremental impact of 0.72 (95% confidence interval (CI) 0.54-0.91) against a lower GOS as compared to 0.6 (95% CI 0.45-0.74) and 0.55 (95% CI 0.42-0.68) for H&H and WFNS grades, respectively. In multivariate categorical analysis, H&H grades 4-5 sans systemic disease had the greatest impact on unfavourable GOS with an adjusted odds ratio of 6.06 (95% CI 3.94-9.32). To conclude, H&H grading sans systemic disease had the greatest impact on unfavourable GOS. Though systemic disease is an important prognostic factor, it should be considered distinctly from grading. Appropriate cut-off values suggesting unfavourable outcome for H&H and WFNS were 4-5 and 3-5, respectively, indicating the importance of neurological deficits in addition to level of consciousness.

  7. Tank 50H Tetraphenylborate Destruction Results

    International Nuclear Information System (INIS)

    Peters, T.B.

    2003-01-01

    We conducted several scoping tests with both Tank 50H surrogate materials (KTPB and phenol) as well as with actual Tank 50H solids. These tests examined whether we could destroy the tetraphenylborate in the surrogates or actual Tank 50H material either by use of Fenton's Reagent or by hydrolysis (in Tank 50H conditions at a maximum temperature of 50 degrees C) under a range of conditions. The results of these tests showed that destruction of the solids occurred only under a minority of conditions. (1)Using Fenton's Reagent and KTPB as the Tank 50H surrogate, no reaction occurred at pH ranges greater than 9. (2)Using Fenton's Reagent and phenol as the Tank 50H surrogate, no reaction occurred at a pH of 14. (3)Using Fenton's Reagent and actual Tank 50H slurry, a reaction occurred at a pH of 9.5 in the presence of ECC additives. (4)Using Fenton's Reagent and actual Tank 50H slurry, after a thirty three day period, all attempts at hydrolysis (at pH 14) were too slow to be viable. This happened even in the case of higher temperature (50 degrees C) and added (100 ppm) copper. Tank 50H is scheduled to return to HLW Tank Farm service with capabilities of transferring and receiving salt supernate solutions to and from the Tank Farms and staging feed for the Saltstone Facility. Before returning Tank 50H to Tank Farm service as a non-organic tank, less than 5 kg of TPB must remain in Tank 50H. Recently, camera inspections in Tank 50H revealed two large mounds of solid material, one in the vicinity of the B5 Riser Transfer Pump and the other on the opposite side of the tank. Personnel sampled and analyzed this material to determine its composition. The sample analysis indicated presence of a significant quantity of organics in the solid material. This quantity of organic material exceeds the 5 kg limit for declaring only trace amounts of organic material remain in Tank 50H. Additionally, these large volumes of solids, calculated as approximately 61K gallons, present other

  8. Theoretical investigation of elementary reaction of complexing LiH+BeH/sub 2/. -->. LiBeH/sub 3/

    Energy Technology Data Exchange (ETDEWEB)

    Charkin, O P; Boldyrev, A I; Sukhanov, L P [AN SSSR, Chernogolovka. Inst. Novykh Khimicheskikh Problem

    1979-01-01

    In the framework of non-empirical Hartree-Fock-Roothaan method on the basis of gauss functions of Roos and Siegbahn made are calculations of different sections of potential surface elementary reaction of complexing LiH+BeH/sub 2/ ..-->.. LiBeH/sub 3/. Charts of potential surface are presented. Questions of the elementary mechanism of elementary processes of complexing and effect of mutual orientation of the reagents upon the reaction mechanism are considered. Stability of LiBeH/sub 3/ molecule to different dissociation channels and different aspects of structural non-rigidity of the L(MXsub(k+1)) complexes at super barrier excitation are discussed.

  9. Theoretical investigation of elementary reaction of complexing LiH+BeH2 → LiBeH3

    International Nuclear Information System (INIS)

    Charkin, O.P.; Boldyrev, A.I.; Sukhanov, L.P.

    1979-01-01

    In the framework of non-empiric Hartree-Fock-Roothaan method on the basis of gauss functions of Roos and Siegbahn made are calculations of different sections of potential surface elementary reaction of complexing LiH+BeH 2 → LiBeH 3 . Charts of potential surface are presented. Questions of the elementary mechanism of elementary processes of complexing and effect of mutual orientation of the reagents upon the reaction mechanism are considered. Stability of LiBeH 3 molecule to different dissociation channels and different aspects of structural non-rigidity of the L[MXsub(k+1)] complexes at super barrier excitation are discussed

  10. Laboratory Measurements for H3+ Deuteration Reactions

    Science.gov (United States)

    Bowen, Kyle; Hillenbrand, Pierre-Michel; Urbain, Xavier; Savin, Daniel Wolf

    2018-06-01

    Deuterated molecules are important chemical tracers of protostellar cores. At the ~106 cm-3 particle densities and ~20 K temperatures typical for protostellar cores, most molecules freeze onto dust grains. A notable exception is H3+ and its isotopologues. These become important carriers of positive charge in the gas, can couple to any ambient magnetic field, and can thereby alter the cloud dynamics. Knowing the total abundance of H3+ and its isotopologues is important for studying the evolution of protostellar cores. However, H3+ and D3+ have no dipole moment. They lack a pure rotational spectrum and are not observable at protostellar core temperatures. Fortunately H2D+ and D2H+ have dipole moments and a pure rotational spectrum that can be excited in protostellar cores. Observations of these two molecules, combined with astrochemical models, provide information about the total abundance of H3+ and all its isotopologues. The inferred abundances, though, rely on accurate astrochemical data for the deuteration of H3+ and its isotopologues.Here we present laboratory measurements of the rate coefficients for three important deuterating reactions, namely D + H3+/H2D+/D2H+ → H + H2D+/ D2H+/D3+. Astrochemical models currently rely on rate coefficients from classical (Langevin) or semi-classical methods for these reactions, as fully quantum-mechanical calculations are beyond current computational capabilities. Laboratory studies are the most tractable means of providing the needed data. For our studies we used our novel dual-source, merged fast-beams apparatus, which enables us to study reactions of neutral atoms and molecular ions. Co-propagating beams allow us to measure experimental rate coefficients as a function of collision energy. We extract cross section data from these results, which we then convolve with a Maxwell-Boltzmann distribution to generate thermal rate coefficients. Here we present our results for these three reactions and discuss some implications.

  11. hPIN/hTAN: Low-Cost e-Banking Secure against Untrusted Computers

    Science.gov (United States)

    Li, Shujun; Sadeghi, Ahmad-Reza; Schmitz, Roland

    We propose hPIN/hTAN, a low-cost token-based e-banking protection scheme when the adversary has full control over the user's computer. Compared with existing hardware-based solutions, hPIN/hTAN depends on neither second trusted channel, nor secure keypad, nor computationally expensive encryption module.

  12. Does GaH5 exist?

    Science.gov (United States)

    Speakman, Lucas D.; Turney, Justin M.; Schaefer, Henry F.

    2005-11-01

    The existence or nonexistence of GaH5 has been widely discussed [N. M. Mitzel, Angew. Chem. Int. Ed. 42, 3856 (2003)]. Seven possible structures for gallium pentahydride have been systematically investigated using ab initio electronic structure theory. Structures and vibrational frequencies have been determined employing self-consistent field, coupled cluster including all single and double excitations (CCSD), and CCSD with perturbative triples levels of theory, with at least three correlation-consistent polarized-valence-(cc-pVXZ and aug-cc-pVXZ) type basis sets. The X˜A'1 state for GaH5 is predicted to be weakly bound complex 1 between gallane and molecular hydrogen, with Cs symmetry. The dissociation energy corresponding to GaH5→GaH3+H2 is predicted to be De=2.05kcalmol-1. The H-H stretching fundamental is predicted to be v =4060cm-1, compared to the tentatively assigned experimental feature of Wang and Andrews [J. Phys. Chem. A 107, 11371 (2003)] at 4087cm-1. A second Cs structure 2 with nearly equal energy is predicted to be a transition state, corresponding to a 90° rotation of the H2 bond. Thus the rotation of the hydrogen molecule is essentially free. However, hydrogen scrambling through the C2v structure 3 seems unlikely, as the activation barrier for scrambling is at least 30kcalmol-1 higher in energy than that for the dissociation of GaH5 to GaH3 and H2. Two additional structures consisting of GaH3 with a dihydrogen bond perpendicular to gallane (C3v structure 4) and an in-plane dihydrogen bond [Cs(III) structure 5] were also examined. A C3v symmetry second-order saddle point has nearly the same energy as the GaH3+H2 dissociation limit, while the Cs(III) structure 5 is a transition structure to the C3v structure. The C4v structure 6 and the D3h structure 7 are much higher in energy than GaH3+H2 by 88 and 103kcalmol-1, respectively.

  13. Dynamic regulation of gastric surface pH by luminal pH

    OpenAIRE

    Chu, Shaoyou; Tanaka, Shin; Kaunitz, Jonathan D.; Montrose, Marshall H.

    1999-01-01

    In vivo confocal imaging of the mucosal surface of rat stomach was used to measure pH noninvasively under the mucus gel layer while simultaneously imaging mucus gel thickness and tissue architecture. When tissue was superfused at pH 3, the 25 μm adjacent to the epithelial surface was relatively alkaline (pH 4.1 ± 0.1), and surface alkalinity was enhanced by topical dimethyl prostaglandin E2 (pH 4.8 ± 0.2). Luminal pH was changed from pH 3 to pH 5 to mimic the fasted-to-fed transition in intra...

  14. 4-H Afterschool – Making an Impact

    Directory of Open Access Journals (Sweden)

    JoLene Bunnell

    2006-06-01

    Full Text Available 4-H Afterschool is making a positive impact on youth, families, and their communities. Utah State University Extension has implemented a 4-H Afterschool club at four elementary schools in low-income neighborhoods. At each of the sites, 4-H offers sixteen different project clubs. Survey results indicate that the 4-H Afterschool program is building positive social skills in the youth, providing positive alternatives to idleness and antisocial behavior, and supporting parents in the primary role of care giving. The Afterschool clubs incorporate project activities, a service learning component, and a final showcase for the parents. Youth development professionals, using the experiential learning model of 4-H, can affect positive change within their communities by implementing a 4-H Afterschool program.

  15. New developments with H-sources

    International Nuclear Information System (INIS)

    Sherman, Joseph D.; Rouleau, G.

    2002-01-01

    Existing spallation neutron source upgrades, planned spallation neutron sources, and high-energy accelerators for particle physics place demanding requirements on the Hsources. These requirements ask for increased beam currents and duty factor (df) while generally maintaining state-of-the art H' source emittance. A variety of H sources are being developed to address these challenges. These include volume sources with and without the addition of cesium for enhanced He production, increased df cesiated H' Penning and magnetron sources, and cesiated surface converter H- sources. Research on surface films of tantalum metal for enhanced volume H- production is also being studied. Innovative plasma production techniques to address the longer df requirement without sacrificing H- source reliability and liktime will be reviewed. The physical bases, the goals, and perceived challenges will be discussed.

  16. Highly precise (liquid + liquid) equilibrium and heat capacity measurements near the critical point for [Bmim][BF4] + 1H, 1H, 2H, 2H perfluoroctanol

    International Nuclear Information System (INIS)

    Pérez-Sánchez, G.; Troncoso, J.; Losada-Pérez, P.; Méndez-Castro, P.; Romaní, L.

    2013-01-01

    Highlights: • Highly precise liquid–liquid curves for [Bmim][BF 4 ] + perfluoroctanol are reported. • Critical behavior of heat capacity for the same system was also characterized. • In contrast to previous results, no coulombic/solvophobic crossover for coexistence curve diameter was found. • The system criticality shows characteristics both solvophobic and coulombic. -- Abstract: Liquid + liquid equilibrium of the system [Bmim][BF 4 ] + 1H, 1H, 2H, 2H perfluoroctanol using a highly precise methodology based on refractive index measurements was experimentally determined. In addition, isobaric heat capacity near the critical point was obtained. The performance of the new refractive index set-up was successfully checked against the coexistence curve of the system dimethyl carbonate + decane, since highly accurate data are available in the literature. The choice of [Bmim][BF 4 ] + 1H, 1H, 2H, 2H perfluoroctanol was motivated by a previous experimental work, whose results suggest that this system could present characteristics of both solvophobic and coulombic behavior, which are the two categories to which an ionic system can belong. Although this was previously observed for other ionic systems, this mixture presented a very striking feature: the diameter of the coexistence curve seemed to change its criticality in the studied temperature range, from solvophobic far away to coulombic close to the critical point. The results of this work reveal that, in fact, [Bmim][BF 4 ] + 1H, 1H, 2H, 2H perfluoroctanol presents characteristics of both solvophobic and coulombic criticality, but no evidence of the observed crossover over the experimental temperature range has been found

  17. Ceramics and M.H.D

    International Nuclear Information System (INIS)

    Yvars, M.

    1979-10-01

    The materials considered for the insulating walls of a M.H.D. converter are Al 2 O 3 , and the calcium or strontium zirconates. For the conducting walls electricity conducting oxides are being considered such as ZrO 2 or CrO 3 La essentially. The principle of M.H.D. systems is recalled, the materials considered are described as is their behaviour in the corrosive atmospheres of M.H.D. streams [fr

  18. Interpolation for a subclass of H

    Indian Academy of Sciences (India)

    |g(zm)| ≤ c |zm − zm |, ∀m ∈ N. Thus it is natural to pose the following interpolation problem for H. ∞. : DEFINITION 4. We say that (zn) is an interpolating sequence in the weak sense for H. ∞ if given any sequence of complex numbers (λn) verifying. |λn| ≤ c ψ(zn,z. ∗ n) |zn − zn |, ∀n ∈ N,. (4) there exists a product fg ∈ H.

  19. pH distribution in human tumors

    International Nuclear Information System (INIS)

    Thistlethwaite, A.J.; Leeper, D.B.; Moylan, D.J.; Nerlinger, R.E.

    1984-01-01

    pH distribution in human tumors is being determined to evaluate this parameter as a prognostic indicator of hyperthermia response. pH is measured by a modified glass pH electrode (21g, model MI 408, Microelectrodes, Inc., Londonderry, NH) inserted through an 18g open-ended Angiocath. Eight tumors have been evaluated to date; and of those, 3 were also assayed after the first heat treatment coincident with determination of blood flow. Tumors were between 2-5 cm, of various histologies, and of primary, recurrent, or metastatic origin. 2-4 measurements were made per tumor. Pretreatment readings were between 6.4 and 7.2 pH units. As tumor blood flow increased after 1 hr heating (41.5 - 43 0 ) pH rose 0.1 - 0.3 units. Normal rat muscle yields pH readings of 7.35 - 7.45. Although there was considerable heterogeneity of pH within tumors, accuracy and drift were not a problem. 5-15 min were required for pH stabilization after catheter insertion and <5 min after electrode insertion. A saline wheal was used for anesthesia to preclude modification of pH by anesthetics. Patient tolerance has not been a problems. This study suggests that human tumor tissue has a preponderance of areas more acidic than normal tissue. This may serve to sensitize tumor cells to hyperthermia and provide a prognostic indicator of tumor response

  20. H2O2: A Dynamic Neuromodulator

    Science.gov (United States)

    Rice, Margaret E.

    2012-01-01

    Increasing evidence implicates hydrogen peroxide (H2O2) as an intra- and intercellular signaling molecule that can influence processes from embryonic development to cell death. Most research has focused on relatively slow signaling, on the order of minutes to days, via second messenger cascades. However, H2O2 can also mediate subsecond signaling via ion channel activation. This rapid signaling has been examined most thoroughly in the nigrostriatal dopamine (DA) pathway, which plays a key role in facilitating movement mediated by the basal ganglia. In DA neurons of the substantia nigra, endogenously generated H2O2 activates ATP-sensitive K+ (KATP) channels that inhibit DA neuron firing. In the striatum, H2O2 generated downstream from glutamatergic AMPA receptor activation in medium spiny neurons acts as a diffusible messenger that inhibits axonal DA release, also via KATP channels. The source of dynamically generated H2O2 is mitochondrial respiration; thus, H2O2 provides a novel link between activity and metabolism via KATP channels. Additional targets of H2O2 include transient receptor potential (TRP) channels. In contrast to the inhibitory effect of H2O2 acting via KATP channels, TRP channel activation is excitatory. This review describes emerging roles of H2O2 as a signaling agent in the nigrostriatal pathway and other basal ganglia neurons. PMID:21666063

  1. Avian Influenza A (H5N1)

    Centers for Disease Control (CDC) Podcasts

    2009-05-27

    In this podcast, CDC's Dr. Tim Uyeki discusses H5N1, a subtype of influenza A virus. This highly pathogenic H5N1 virus doesn't usually infect people, although some rare infections with H5N1 viruses have occurred in humans. We need to use a comprehensive strategy to prevent the spread of H5N1 virus among birds, including having human health and animal health work closely together.  Created: 5/27/2009 by Emerging Infectious Diseases.   Date Released: 5/27/2009.

  2. Functional photoacoustic microscopy of pH.

    Science.gov (United States)

    Chatni, Muhammad Rameez; Yao, Junjie; Danielli, Amos; Favazza, Christopher P; Maslov, Konstantin I; Wang, Lihong V

    2011-10-01

    pH is a tightly regulated indicator of metabolic activity. In mammalian systems, an imbalance of pH regulation may result from or result in serious illness. In this paper, we report photoacoustic microscopy (PAM) of a commercially available pH-sensitive fluorescent dye (SNARF-5F carboxylic acid) in tissue phantoms. We demonstrated that PAM is capable of pH imaging in absolute values at tissue depths of up to 2.0 mm, greater than possible with other forms of optical microscopy.

  3. Nonperfect synchronization of bond-forming and bond-rupturing processes in the reaction H + H2 → H2 + H

    International Nuclear Information System (INIS)

    Chandra, A.K.; Rao, V.S.

    1996-01-01

    The simplest prototypical hydrogen transfer reaction, i.e., H + H 2 → H 2 + H, is studied by the quantum-mechanical ab initio methods. Results reveal that during this reaction free valence which almost equals the square of the spin density develops on the migrating hydrogen atom. Bond orders are calculated using Mayer's formalism. Both the variations of bond orders and bond lengths along the reaction path are examined. This analysis reveals that the bond formation and bond cleavage processes in this reaction are not perfectly synchronous. The bond clevage process is slightly more advanced on the reaction path. 38 refs., 6 figs., 2 tabs

  4. Differential Calculus on h-Deformed Spaces

    Science.gov (United States)

    Herlemont, Basile; Ogievetsky, Oleg

    2017-10-01

    We construct the rings of generalized differential operators on the h-deformed vector space of gl-type. In contrast to the q-deformed vector space, where the ring of differential operators is unique up to an isomorphism, the general ring of h-deformed differential operators {Diff}_{h},σ(n) is labeled by a rational function σ in n variables, satisfying an over-determined system of finite-difference equations. We obtain the general solution of the system and describe some properties of the rings {Diff}_{h},σ(n).

  5. Dissociative recombination of molecular ions H2+

    International Nuclear Information System (INIS)

    Abarenov, A.V.; Marchenko, V.S.

    1989-01-01

    The total cross sections of dissociation and dissociative recombination of slow electrons and molecular ions H 2 + have been calculated in terms of the quasiclassical and dipole approximations. In the calculations allowance was made for the quantum nature of vibrational motion of heavy particles and presence of autoionization of divergence states of the H 2 (Σ u , nl) molecules. It is shown that the H 2 + ion dissociation cross sections are dominant in increase of the electron energy in the ε >or approx. 2-3 eV region for H 2 + (v) ion distribution over the vibrational levels characteristic for the beam experiments. 15 refs.; 5 figs

  6. Uses of monoclonal antibody 8H9

    Energy Technology Data Exchange (ETDEWEB)

    Cheung, Nai-Kong V.

    2018-04-10

    This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides a method of inhibiting the growth of tumor cells comprising contacting said tumor cells with an appropriate amount of monoclonal antibody 8H9 or a derivative thereof.

  7. Measurement of imino {sup 1}H-{sup 1}H residual dipolar couplings in RNA

    Energy Technology Data Exchange (ETDEWEB)

    Latham, Michael P. [University of Toronto, Department of Molecular Genetics (Canada); Pardi, Arthur [University of Colorado, Department of Chemistry and Biochemistry, 215 UCB (United States)], E-mail: arthur.pardi@colorado.edu

    2009-02-15

    Imino {sup 1}H-{sup 15}N residual dipolar couplings (RDCs) provide additional structural information that complements standard {sup 1}H-{sup 1}H NOEs leading to improvements in both the local and global structure of RNAs. Here, we report measurement of imino {sup 1}H-{sup 1}H RDCs for the Iron Responsive Element (IRE) RNA and native E. coli tRNA{sup Val} using a BEST-Jcomp-HMQC2 experiment. {sup 1}H-{sup 1}H RDCs are observed between the imino protons in G-U wobble base pairs and between imino protons on neighboring base pairs in both RNAs. These imino {sup 1}H-{sup 1}H RDCs complement standard {sup 1}H-{sup 15}N RDCs because the {sup 1}H-{sup 1}H vectors generally point along the helical axis, roughly perpendicular to {sup 1}H-{sup 15}N RDCs. The use of longitudinal relaxation enhancement increased the signal-to-noise of the spectra by {approx}3.5-fold over the standard experiment. The ability to measure imino {sup 1}H-{sup 1}H RDCs offers a new restraint, which can be used in NMR domain orientation and structural studies of RNAs.

  8. Photolysis of H2O-H2O2 Mixtures: The Destruction of H2O2

    Science.gov (United States)

    Loeffler, M. J.; Fama, M.; Baragiola, R. A.; Carlson, R. W.

    2013-01-01

    We present laboratory results on the loss of H2O2 in solid H2O + H2O2 mixtures at temperatures between 21 and 145 K initiated by UV photolysis (193 nm). Using infrared spectroscopy and microbalance gravimetry, we measured the decrease of the 3.5 micrometer infrared absorption band during UV irradiation and obtained a photodestruction cross section that varies with temperature, being lowest at 70 K. We use our results, along with our previously measured H2O2 production rates via ionizing radiation and ion energy fluxes from the spacecraft to compare H2O2 creation and destruction at icy satellites by ions from their planetary magnetosphere and from solar UV photons. We conclude that, in many cases, H2O2 is not observed on icy satellite surfaces because the H2O2 photodestruction rate is much higher than the production rate via energetic particles, effectively keeping the H2O2 infrared signature at or below the noise level.

  9. Interference of transcription across H-NS binding sites and repression by H-NS.

    Science.gov (United States)

    Rangarajan, Aathmaja Anandhi; Schnetz, Karin

    2018-05-01

    Nucleoid-associated protein H-NS represses transcription by forming extended DNA-H-NS complexes. Repression by H-NS operates mostly at the level of transcription initiation. Less is known about how DNA-H-NS complexes interfere with transcription elongation. In vitro H-NS has been shown to enhance RNA polymerase pausing and to promote Rho-dependent termination, while in vivo inhibition of Rho resulted in a decrease of the genome occupancy by H-NS. Here we show that transcription directed across H-NS binding regions relieves H-NS (and H-NS/StpA) mediated repression of promoters in these regions. Further, we observed a correlation of transcription across the H-NS-bound region and de-repression. The data suggest that the transcribing RNA polymerase is able to remodel the H-NS complex and/or dislodge H-NS from the DNA and thus relieve repression. Such an interference of transcription and H-NS mediated repression may imply that poorly transcribed AT-rich loci are prone to be repressed by H-NS, while efficiently transcribed loci escape repression. © 2018 John Wiley & Sons Ltd.

  10. Enzymatic and hormonal responses following a 24 h endurance run and a 10 h triathlon race.

    Science.gov (United States)

    Fellmann, N; Sagnol, M; Bedu, M; Falgairette, G; Van Praagh, E; Gaillard, G; Jouanel, P; Coudert, J

    1988-01-01

    Muscle cell leakage and hormonal changes were compared immediately after and during the 3 days following a 24 h endurance run (R24h) in 8 subjects, and a 10 h triathlon non-competitive race (T10h) in 6 subjects. The study showed three main differences: 1) plasma enzyme increases were considerably more significant in R24h than in T10h: compared with resting levels, creatine kinase increased x 120 after R24h but only x 2 after T10h; lactic dehydrogenase x 4, as opposed to x 1.5; and transaminases only showed an increase after R24h. The plasma myoglobin increase after R24h was double that found after T10h; 2) for the same magnitude of plasma aldosterone and cortisol after R24h and T10h (3 times the resting levels), a highly significant decrease in urinary Na+ (p less than 0.001) and an increase in urinary K+ (p less than 0.01) were found only after R24h; and 3) the plasma free noradrenaline level increased significantly after R24h (x 2.6) whereas it was unchanged after T10h. In contrast, the plasma level of conjugated dopamine increased only after T10h (x 3.7, p less than 0.05). These results suggest that long-distance running causes more muscular lesions than the triathlon, and that important factors other than aldosterone are probably involved in the regulation of urinary electrolyte excretions during T10h.

  11. Salivary pH: A diagnostic biomarker

    Directory of Open Access Journals (Sweden)

    Sharmila Baliga

    2013-01-01

    Full Text Available Objectives: Saliva contains a variety of host defense factors. It influences calculus formation and periodontal disease. Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease. With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test. The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease. Study Design: The study population consisted of 300 patients. They were divided into three groups of 100 patients each: Group A had clinically healthy gingiva, Group B who had generalized chronic gingivitis and Group C who had generalized chronic periodontitis. The randomized unstimulated saliva from each patient was collected and pH was tested. Data was analyzed statistically using analysis of variance technique. Results: The salivary pH was more alkaline for patients with generalized chronic gingivitis as compared with the control group (P = 0.001 whereas patients with generalized chronic periodontitis had more acidic pH as compared with the control group (P = 0.001. Conclusion: These results indicate a significant change in the pH depending on the severity of the periodontal condition. The salivary pH shows significant changes and thus relevance to the severity of periodontal disease. Salivary pH may thus be used as a quick chairside diagnostic biomarker.

  12. Salivary pH: A diagnostic biomarker.

    Science.gov (United States)

    Baliga, Sharmila; Muglikar, Sangeeta; Kale, Rahul

    2013-07-01

    Saliva contains a variety of host defense factors. It influences calculus formation and periodontal disease. Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease. With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test. The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease. The study population consisted of 300 patients. They were divided into three groups of 100 patients each: Group A had clinically healthy gingiva, Group B who had generalized chronic gingivitis and Group C who had generalized chronic periodontitis. The randomized unstimulated saliva from each patient was collected and pH was tested. Data was analyzed statistically using analysis of variance technique. The salivary pH was more alkaline for patients with generalized chronic gingivitis as compared with the control group (P = 0.001) whereas patients with generalized chronic periodontitis had more acidic pH as compared with the control group (P = 0.001). These results indicate a significant change in the pH depending on the severity of the periodontal condition. The salivary pH shows significant changes and thus relevance to the severity of periodontal disease. Salivary pH may thus be used as a quick chairside diagnostic biomarker.

  13. The H-mode of ASDEX

    International Nuclear Information System (INIS)

    1989-01-01

    The paper is a review of investigations of the H-mode on ASDEX performed since its discovery in 1982. The topics discussed are: (1) the development of the plasma profiles, with steep gradients in the edge region and flat profiles in the bulk plasma, (2) the MHD properties resulting from the profile changes, including an extensive stability analysis, (3) the impurity development, with special emphasis on the MHD aspects and on neoclassical impurity transport effects in quiescent H-phases, and (4) the properties of the edge plasma, including the evidence of three-dimensional distortions at the edge. The part on confinement includes scaling studies and the results of transport analysis. The power threshold of the H-mode is found to depend weakly on the density, but there is probably no dependence on the toroidal field or the current. For the operational range of the H-mode, new results for the limiter H-mode on ASDEX and the development of the H-mode under beam current drive conditions are included. A number of experiments are described which demonstrate the crucial role of the edge electron temperature in the L-H transition. New results of magnetic and density fluctuation studies at the plasma edge within the edge transport barrier are presented. Finally, the findings on ASDEX are compared with results obtained on other machines and are used to test various H-mode theories. (author). 131 refs, 103 figs, 1 tab

  14. Tank 12H residuals sample analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Shine, E. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Diprete, D. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Coleman, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hay, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-06-11

    The Savannah River National Laboratory (SRNL) was requested by Savannah River Remediation (SRR) to provide sample preparation and analysis of the Tank 12H final characterization samples to determine the residual tank inventory prior to grouting. Eleven Tank 12H floor and mound residual material samples and three cooling coil scrape samples were collected and delivered to SRNL between May and August of 2014.

  15. The rotational excitation of HF by H

    Science.gov (United States)

    Desrousseaux, Benjamin; Lique, François

    2018-06-01

    The HF molecule is a key tracer of molecular hydrogen in diffuse interstellar medium (ISM). Accurate modelling of the HF abundance in such media requires one to model its excitation by both radiation and collisions. In diffuse ISM, the dominant collisional partners are atomic and molecular hydrogen. We report quantum time-independent calculations of collisional cross-sections and rate coefficients for the rotational excitation of HF by H. The reactive hydrogen exchange channels are taken into account in the scattering calculations. For the first time, HF-H rate coefficients are provided for temperature ranging from 10 to 500 K. The strongest collision-induced rotational HF transitions are those with Δj = 1, and the order of magnitude of the new HF-H rate coefficients is similar to that of the HF-H2 ones previously computed. As a first application, we simulate the excitation of HF by both H and H2 in typical diffuse ISM. We show that, depending on the rotational transition, hydrogen atoms increase or decrease the simulated excitation temperatures compared to collisional excitation only due to H2 molecules. Such results suggest that the new HF-H collisional data have to be used for properly modelling the abundance of HF in diffuse ISM.

  16. [Radiocompetitive method of H antigen determination].

    Science.gov (United States)

    Semenova, G B; Sokolov, Ia A; Liashenko, V A

    1978-06-01

    The authors describe a radiocompetitive method of H-d-monomere determination with the sensitivity of 2 ng/ml in double antibodies modification; this method was used for comparing the immunological affinity of the affiliated H-antigens. A difference between the immunological affinity to the antibodies in a monomere, polymere and the flagellum was shown.

  17. The H+ molecule in strong magnetic fields

    International Nuclear Information System (INIS)

    Melo, L.C. de; Das, T.K.; Ferreira, R.; Miranda, L.C.M.; Brandi, H.S.

    1976-01-01

    A LCAO-MO treatment of the H 2 + based on hydrogen-like atomic orbitals is described. Trial wave functions to calculate binding energy and potential curves of H 2 + in the presence of magnetic fields in the range 10 8 G 10 G, are used [pt

  18. On Calibration of pH Meters

    Directory of Open Access Journals (Sweden)

    Da-Ming Zhu

    2005-04-01

    Full Text Available The calibration of pH meters including the pH glass electrode, ISE electrodes,buffers, and the general background for calibration are reviewed. Understanding of basicconcepts of pH, pOH, and electrode mechanism is emphasized. New concepts of pH, pOH,as well as critical examination of activity, and activity coefficients are given. Theemergence of new solid state pH electrodes and replacement of the salt bridge with aconducting wire have opened up a new horizon for pH measurements. A pH buffer solutionwith a conducting wire may be used as a stable reference electrode. The misleadingunlimited linear Nernstian slope should be discarded. Calibration curves with 3 nonlinearportions for the entire 0—14 pH range due to the isoelectric point change effect areexplained. The potential measurement with stirring or unstirring and effects by double layer(DL and triple layer (TL will be discussed.

  19. Triangulation applied to Jan H. van Bemmel

    NARCIS (Netherlands)

    Hasman, A.; Bergemann, D.; McCray, A. T.; Talmon, J. L.; Zvárová, J.

    2006-01-01

    OBJECTIVE: To describe the person of Jan H. van Bemmel from different points of view. METHOD: Triangulation. RESULTS AND CONCLUSIONS: Jan H. van Bemmel successfully contributed to research and education in medical informatics. He inspired a lot of people in The Netherlands and internationally

  20. Photoswitchable Intramolecular H-Stacking of Perylenebisimide

    NARCIS (Netherlands)

    Wang, Jiaobing; Kulago, Artem; Browne, Wesley R.; Feringa, Ben L.

    2010-01-01

    Dynamic control over the formation of H- or J-type aggregates of chromophores is of fundamental importance for developing responsive organic optoelectronic materials. In this study, the first example of photoswitching between a nonstacked and an intramolecularly H-stacked arrangement of

  1. Semiglobal H-infty state feedback control

    DEFF Research Database (Denmark)

    Cromme, Marc

    1997-01-01

    semi-global set-stabilizing H-infty control is local H-infty control within some given compact set O such that all state trajectories are bounded inside O, and are approaching an open loop invariant set S subset O as t -> infinity. Sufficient conditions for the existance of a continuous statefeed...

  2. Charge transfer processes in collisions of H+ ions with H2, D2, CO, CO2 CH4, C2H2, C2H6 and C3H8 molecules below 10 keV

    International Nuclear Information System (INIS)

    Kusakabe, T.; Buenker, R.J.; Kimura, M.

    2002-01-01

    Charge transfer processes resulting from collisions of H + ions with H 2 , D 2 , CO, CO 2 CH 4 , C 2 H 2 , C 2 H 6 and C 3 H 8 molecules have been investigated in the energy range of 0.2 to 4.0 keV experimentally and theoretically. The initial growth rate method was employed in the experiment for studying the dynamics and cross sections. Theoretical analysis based on a molecular-orbital expansion method for H 2 , D 2 , CO, CH 4 and C 2 H 2 targets was also carried out. The present results for the H 2 , CO and CO 2 molecules by H + impact are found to be in excellent accord with most of previous measurements above 1 keV, but they show some differences below this energy where our result displays a stronger energy-dependence. For CH 4 , C 2 H 2 , C 2 H 6 and C 3 H 8 targets, both experimental and theoretical results indicate that if one assumes vibrationally excited molecular ions (CH 4 + , C 2 H 2 + , C 2 H 6 + and C 3 H 8 + ) formed in the exit channel, then charge transfer processes sometimes become more favorable since these vibrationally excited fragments meet an accidental resonant condition. This is a clear indication of the role of vibrational excited states for charge transfer, and is an important realization for general understanding. (author)

  3. H2-H2O-HI Hydrogen Separation in H2-H2O-HI Gaseous Mixture Using the Silica Membrane

    International Nuclear Information System (INIS)

    Pandiangan, Tumpal

    2002-01-01

    It was evaluated aiming at the application for hydrogen iodide decomposition in the thermochemical lS process. Porous alumina tube having pore size of 0.1 μm was modified by chemical vapor deposition using tetraethoxysilane. The permeance single gas of He, H 2 , and N 2 was measured at 300-600 o C. Hydrogen permeance of the modified membrane at a permeation temperature of 600 o C was about 5.22 x 10 -08 mol/Pa m 2 s, and 3.2 x 10 -09 of using gas mixture of H 2 -H 2 O-HI, where as HI permeances was below 1 x 10 -10 mol/Pa m 2 s. The Hydrogen permeance relative was not changed after 25 hours exposure in a mixture of H 2 -H 2 O-HI gas at the temperature of 450 o C. (author)

  4. Spectroscopic determination of pH

    International Nuclear Information System (INIS)

    Faanu, A.; Glover, E.T.; Bailey, E.; Rochelle, C.

    2009-01-01

    A technique of measuring pH at temperature range of 20 - 70 0 C and high pressure conditions of 1 - 200 atmospheres has been developed by relating the ratio of absorbance peaks of indicator solutions (basic and acidic) as a function of pH, using ultraviolet-visible spectrophotometer. The pH values of the buffer solutions measured at 20 0 C and 70 0 C indicated slight temperature dependence, while the pressure had no effect. The pH of the buffer solutions increased with temperature with relative standard deviations in the range 0.4 - 0.5 % at 95 % confidence interval. The possible causes of the temperature dependence were attributed to changes in pH values as the temperature changed. (au)

  5. Endoscopic sensing of alveolar pH.

    Science.gov (United States)

    Choudhury, D; Tanner, M G; McAughtrie, S; Yu, F; Mills, B; Choudhary, T R; Seth, S; Craven, T H; Stone, J M; Mati, I K; Campbell, C J; Bradley, M; Williams, C K I; Dhaliwal, K; Birks, T A; Thomson, R R

    2017-01-01

    Previously unobtainable measurements of alveolar pH were obtained using an endoscope-deployable optrode. The pH sensing was achieved using functionalized gold nanoshell sensors and surface enhanced Raman spectroscopy (SERS). The optrode consisted of an asymmetric dual-core optical fiber designed for spatially separating the optical pump delivery and signal collection, in order to circumvent the unwanted Raman signal generated within the fiber. Using this approach, we demonstrate a ~100-fold increase in SERS signal-to-fiber background ratio, and demonstrate multiple site pH sensing with a measurement accuracy of ± 0.07 pH units in the respiratory acini of an ex vivo ovine lung model. We also demonstrate that alveolar pH changes in response to ventilation.

  6. New borohydride anion B6H7-

    International Nuclear Information System (INIS)

    Kuznetsov, I.Yu.; Vinitskij, D.M.; Solntsev, K.A.

    1985-01-01

    The [Ni(Bipy) 3 ] (B 6 H 7 ) 2 , (Ph 4 P)B 6 H 7 , [Ni(Phen) 3 ](B 6 H 7 ) 2 crystals (where Bipy = bipyridine, Phen = phenathroline, Ph = phenyl) are obtained via the exchange reaction with a subsequent recrystallization from aqua-acetonic and acetonic solutions. The structure is studied of a new borohydride anion B 6 H 7 - possessing a four-valence bond unique for polyhedral borohydride anions. A triangular face of boride skeleton coordinating a hydrogen atom is considerably larger than other faces, and the electron density on this hydrogen atom is evidently much higher than at the end hydride hydrogen atoms. The trend of B 6 H 7 - anion to form statistically disordered structurs testifies to a rather slight effect of the seventh hydrogen atom position on the structure pattern of the ionic crystal lattice

  7. Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin

    OpenAIRE

    Qi, Li; Pujanauski, Lindsey M.; Davis, A. Sally; Schwartzman, Louis M.; Chertow, Daniel S.; Baxter, David; Scherler, Kelsey; Hartshorn, Kevan L.; Slemons, Richard D.; Walters, Kathie-Anne; Kash, John C.; Taubenberger, Jeffery K.

    2014-01-01

    ABSTRACT Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric 1918 virus expressing a contemporary avian H1 hemagglutinin, however, displayed murine pathogenicity indistinguishable from that of the 1918 virus. Here, isogenic chimeric avian influenza viruses were constructed on an avian influenza virus backb...

  8. Tug-of-war between classical and multicenter bonds in H-(Be)n-H species

    Science.gov (United States)

    Lundell, Katie A.; Boldyrev, Alexander I.

    2018-05-01

    Quantum chemical calculations were performed for beryllium homocatenated compounds [H-(Be)n-H]. Global minimum structures were found using machine searches (Coalescence Kick method) with density functional theory. Chemical bonding analysis was performed with the Adaptive Natural Density Partitioning method. It was found that H-(Be)2-H and H-(Be)3-H clusters are linear with classical two-center two-electron bonds, while for n > 3, three-dimensional structures are more stable with multicenter bonding. Thus, at n = 4, multicenter bonding wins the tug-of-war vs. the classical bonding.

  9. Neutron scattering studies of the H2a-H2b and (H3-H4)2 histone complexes

    International Nuclear Information System (INIS)

    Carlson, R.D.

    1984-01-01

    Neutron scattering experiments have shown that both the (H3-H4)2 and H2a-H2b histone complexes are quite asymmetric in solution. The (H3-H4)2 tetramer is an oblate or flattened structure, with a radius of gyration almost as large as that of the core octamer. If the tetramer is primarily globular, it must have an axial ratio of about 1:5. It is more likely, however, that this asymmetry results in part from N-terminal arms that extend outward approximately within the major plane of the particle. If this is the case, less asymmetric models for the globular part of the tetramer, including a dislocated disk of the type proposed by Klug et al. (23), can be made consistent with the scattering data. The H2a-H2b dimer, on the other hand, is an elongated structure. The low resolution data are in good agreement with those calculated for a cylindrical model 64 X 27 A, but other elongated models fit those data almost as well, including one that approximates free N-terminal arms at each end. Free arms are not necessary, but they must extend from the ends if they exist. A contrast matching experiment done with 50% deuterated H2b and undeuterated H2a in the reconstituted dimer showed that these two histones must each be rather elongated within the complex and are not just confined to one end. The amount of scattering contrast between the undeuterated and 50% deuterated histones was sufficient to suggest further experiments using complexes reconstituted from mixtures of undeuterated and partially deuterated histones which will help elucidate their arrangement within the histone complexes and within the octamer core of the nucleosome core particle

  10. Present status of two R.F. heating schemes: I.C.R.H. and L.H.R.H

    International Nuclear Information System (INIS)

    Consoli, T.

    1977-01-01

    Among the large number of wave-plasma interaction, Ion-Cyclotron Resonant Heating (I.C.R.H.) and Lower Hybrid Resonant Heating (L.H.R.H.), are two promising additional R.F. heating schemes for toroidal hot plasma. They both offer the advantage of using power generators which requires a moderate development for next generation machines. It seems important to try to state in the limits of this paper the present experimental situation of these two R.F. heating methods as it results from the vast literature published from the last European Conference

  11. Defense In-Depth Accident Analysis Evaluation of Tritium Facility Bldgs. 232-H, 233-H, and 234-H

    Energy Technology Data Exchange (ETDEWEB)

    Blanchard, A.

    1999-05-10

    'The primary purpose of this report is to document a Defense-in-Depth (DID) accident analysis evaluation for Department of Energy (DOE) Savannah River Site (SRS) Tritium Facility Buildings 232-H, 233-H, and 234-H. The purpose of a DID evaluation is to provide a more realistic view of facility radiological risks to the offsite public than the bounding deterministic analysis documented in the Safety Analysis Report, which credits only Safety Class items in the offsite dose evaluation.'

  12. A voltage-gated H+ channel underlying pH homeostasis in calcifying coccolithophores.

    Directory of Open Access Journals (Sweden)

    Alison R Taylor

    2011-06-01

    Full Text Available Marine coccolithophorid phytoplankton are major producers of biogenic calcite, playing a significant role in the global carbon cycle. Predicting the impacts of ocean acidification on coccolithophore calcification has received much recent attention and requires improved knowledge of cellular calcification mechanisms. Uniquely amongst calcifying organisms, coccolithophores produce calcified scales (coccoliths in an intracellular compartment and secrete them to the cell surface, requiring large transcellular ionic fluxes to support calcification. In particular, intracellular calcite precipitation using HCO₃⁻ as the substrate generates equimolar quantities of H+ that must be rapidly removed to prevent cytoplasmic acidification. We have used electrophysiological approaches to identify a plasma membrane voltage-gated H+ conductance in Coccolithus pelagicus ssp braarudii with remarkably similar biophysical and functional properties to those found in metazoans. We show that both C. pelagicus and Emiliania huxleyi possess homologues of metazoan H(v1 H+ channels, which function as voltage-gated H+ channels when expressed in heterologous systems. Homologues of the coccolithophore H+ channels were also identified in a diversity of eukaryotes, suggesting a wide range of cellular roles for the H(v1 class of proteins. Using single cell imaging, we demonstrate that the coccolithophore H+ conductance mediates rapid H+ efflux and plays an important role in pH homeostasis in calcifying cells. The results demonstrate a novel cellular role for voltage gated H+ channels and provide mechanistic insight into biomineralisation by establishing a direct link between pH homeostasis and calcification. As the coccolithophore H+ conductance is dependent on the trans-membrane H+ electrochemical gradient, this mechanism will be directly impacted by, and may underlie adaptation to, ocean acidification. The presence of this H+ efflux pathway suggests that there is no obligate

  13. Plasmalemmal V-H+-ATPases regulate intracellular pH in human lung microvascular endothelial cells

    International Nuclear Information System (INIS)

    Rojas, Jose D.; Sennoune, Souad R.; Maiti, Debasish; Martinez, Gloria M.; Bakunts, Karina; Wesson, Donald E.; Martinez-Zaguilan, Raul

    2004-01-01

    The lung endothelium layer is exposed to continuous CO 2 transit which exposes the endothelium to a substantial acid load that could be detrimental to cell function. The Na + /H + exchanger and HCO 3 - -dependent H + -transporting mechanisms regulate intracellular pH (pH cyt ) in most cells. Cells that cope with high acid loads might require additional primary energy-dependent mechanisms. V-H + -ATPases localized at the plasma membranes (pmV-ATPases) have emerged as a novel pH regulatory system. We hypothesized that human lung microvascular endothelial (HLMVE) cells use pmV-ATPases, in addition to Na + /H + exchanger and HCO 3 - -based H + -transporting mechanisms, to maintain pH cyt homeostasis. Immunocytochemical studies revealed V-H + -ATPase at the plasma membrane, in addition to the predicted distribution in vacuolar compartments. Acid-loaded HLMVE cells exhibited proton fluxes in the absence of Na + and HCO 3 - that were similar to those observed in the presence of either Na + , or Na + and HCO 3 - . The Na + - and HCO 3 - -independent pH cyt recovery was inhibited by bafilomycin A 1 , a V-H + -ATPase inhibitor. These studies show a Na + - and HCO 3 - -independent pH cyt regulatory mechanism in HLMVE cells that is mediated by pmV-ATPases

  14. Comparative pathology of pigs infected with Korean H1N1, H1N2, or H3N2 swine influenza A viruses

    OpenAIRE

    Lyoo, Kwang-Soo; Kim, Jeong-Ki; Jung, Kwonil; Kang, Bo-Kyu; Song, Daesub

    2014-01-01

    Background The predominant subtypes of swine influenza A virus (SIV) in Korea swine population are H1N1, H1N2, and H3N2. The viruses are genetically close to the classical U.S. H1N1 and triple-reassortant H1N2 and H3N2 viruses, respectively. Comparative pathogenesis caused by Korean H1N1, H1N2, and H3N2 SIV was evaluated in this study. Findings The H3N2 infected pigs had severe scores of gross and histopathological lesions at post-inoculation days (PID) 2, and this then progressively decrease...

  15. Determination of the intracellular pH of intact erythrocytes by 1H NMR spectroscopy

    International Nuclear Information System (INIS)

    Rabenstein, D.L.; Isab, A.A.

    1982-01-01

    A method is described for determining the intracellular pH of intact erythrocytes by 1 H NMR. The determination is based on the pH dependence of the chemical shifts of resonances for carbon-bounded protons of an indicator molecule (imidazole) in intact cells. The imidazole is introduced into the erythrocytes by incubation in an isotonic saline solution of the indicator. The pH dependence of the chemical shifts of the imidazole resonances is calibrated from 1 H NMR spectra of the imidazole-containing red cell lysates whose pH is varied by the addition of acid or base and measured directly with a pH electrode. To reduce in intensity or eliminate the much more intense envelope of resonances from the hemoglobin, the 1 H NMR measurements are made by either the spin-echo Fourier transform technique or by the transfer-or-saturation by cross-relaxation method

  16. Synthesis of fixed-architecture, robust H 2 and H ∞ controllers

    Directory of Open Access Journals (Sweden)

    Collins Jr. Emmanuel G.

    2000-01-01

    Full Text Available This paper discusses and compares the synthesis of fixed-architecture controllers that guarantee either robust H 2 or H ∞ performance. The synthesis is accomplished by solving a Riccati equation feasibility problem resulting from mixed structured singular value theory with Popov multipliers. Whereas the algorithm for robust H 2 performance had been previously implemented, a major contribution described in this paper is the implementation of the much more complex algorithm for robust H ∞ performance. Both robust H 2 and H ∞ , controllers are designed for a benchmark problem and a comparison is made between the resulting controllers and control algorithms. It is found that the numerical algorithm for robust H ∞ performance is much more computationally intensive than that for robust H 2 performance. Both controllers are found to have smaller bandwidth, lower control authority and to be less conservative than controllers obtained using complex structured singular value synthesis

  17. 24-h Efficacy of Glaucoma Treatment Options.

    Science.gov (United States)

    Konstas, Anastasios G P; Quaranta, Luciano; Bozkurt, Banu; Katsanos, Andreas; Garcia-Feijoo, Julian; Rossetti, Luca; Shaarawy, Tarek; Pfeiffer, Norbert; Miglior, Stefano

    2016-04-01

    Current management of glaucoma entails the medical, laser, or surgical reduction of intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate with either stability or delayed progression of visual loss. In the published literature, the hypothesis is often made that IOP control implies a single IOP measurement over time. Although the follow-up of glaucoma patients with single IOP measurements is quick and convenient, such measurements often do not adequately reflect the untreated IOP characteristics, or indeed the quality of treated IOP control during the 24-h cycle. Since glaucoma is a 24-h disease and the damaging effect of elevated IOP is continuous, it is logical that we should aim to understand the efficacy of all treatment options throughout the 24-h period. This article first reviews the concept and value of diurnal and 24-h IOP monitoring. It then critically evaluates selected available evidence on the 24-h efficacy of medical, laser and surgical therapy options. During the past decade several controlled trials have significantly enhanced our understanding on the 24-h efficacy of all glaucoma therapy options. Nevertheless, more long-term evidence is needed to better evaluate the 24-h efficacy of glaucoma therapy and the precise impact of IOP characteristics on glaucomatous progression and visual prognosis.

  18. Dissociative charge exchange of H2+

    International Nuclear Information System (INIS)

    Bruijn, D. de.

    1983-01-01

    This thesis is devoted to molecular dissociation, in particular the dissociation of the hydrogen molecule H 2 arising from electron capture of its ion H 2 + in a collision. Thereby the important practical question how a chemical bond can be broken is implicitly addressed. This thesis opens (chapter I) with an overview of the available experimental approaches in molecular physics. Further the simple Demkov model for NRCE is described. In chapter II a novel experimental technique for measurements on dissociative processes is introduced which combines a high efficiency with a high energy resolution. A detailed description of the techniques applied in the detector, which has a high spatial and timing resolution with 30 μm and 350 psec FWHM respectively for the detection of one particle, is given in chapter III. A semi-classical theory for NRCE in the medium energy range between a diatomic molecular ion and an atom is developed in chapter IV. The experiments on dissociative charge exchange of H 2 + with Ar, Mg, Na and Cs targets at keV energies are described in Chapter V. The predissociation of the c 3 PIsub(u)-state of H 2 populated after charge exchange of H 2 with several targets at keV energies; is the subject of chapter VI. In chapter VII, orientational oscillations in the cross section for charge exchange of H 2 + with alkali targets are discussed. The last chapter deals with predissociation of highly excited states in H 2 . (Auth.)

  19. Fallout 3H ingestion in Akita, Japan

    International Nuclear Information System (INIS)

    Hisamatsu, S.; Takizawa, Y.; Abe, T.; Katsumata, T.

    1987-01-01

    To study fallout 3 H ingestion in Japan, 16 separate food group samples were collected from Akita during 1985. The 3 H concentration in free water and that in a tissue-bound form were determined separately. The average 3 H concentration in the tissue-bound form was 2.2 Bq L-1, 1.7 times higher than in the free water of the food. The ingestions of 3 H in the tissue-bound form and as free water in the diet were 0.60 Bq d-1 and 1.0 Bq d-1, respectively. Cereals represented the food group that contributed the most to the ingestion of tissue-bound 3 H. Total 3 H ingestion was estimated to be 4.1 Bq d-1. The contribution of the tissue-bound form to the total ingestion was 15%, considerably lower than reported for Italian diets. The ratio of 3 H ingestion in the tissue-bound form to the free water form in the diet was similar to the ratio reported for New York City

  20. Role of dust in H II regions

    International Nuclear Information System (INIS)

    Sarazin, C.L.

    1975-01-01

    The purpose of this dissertation is to determine quantitatively the effects of U.V. absorbing dust on H II regions, and compare these effects with observations. Many observations indicate that dust grains are present within H II regions. An analytic theory is presented which describes all three of the effects of dust in H II regions. Although this model is relatively crude, it is useful in determining the approximate size of the modifications due to dust. In order to explore this problem more carefully, detailed numerical models of H II regions with dust were constructed. The ionization and thermal structure of these model H II regions is discussed. The observational consequences of the presence of dust are explored; the optical line intensities, radio continuum and line fluxes, and infrared emission of model H II regions with dust are given. These numerical models are compared with observations of diffuse nebulae. The optical line ratios are compared to several nearby bright H II regions, and it is found that the dust models may explain several anomalies in their spectrum

  1. Centralized Consensus Hemagglutinin Genes Induce Protective Immunity against H1, H3 and H5 Influenza Viruses.

    Directory of Open Access Journals (Sweden)

    Richard J Webby

    Full Text Available With the exception of the live attenuated influenza vaccine there have been no substantial changes in influenza vaccine strategies since the 1940's. Here we report an alternative vaccine approach that uses Adenovirus-vectored centralized hemagglutinin (HA genes as vaccine antigens. Consensus H1-Con, H3-Con and H5-Con HA genes were computationally derived. Mice were immunized with Ad vaccines expressing the centralized genes individually. Groups of mice were vaccinated with 1 X 1010, 5 X 107 and 1 X 107 virus particles per mouse to represent high, intermediate and low doses, respectively. 100% of the mice that were vaccinated with the high dose vaccine were protected from heterologous lethal challenges within each subtype. In addition to 100% survival, there were no signs of weight loss and disease in 7 out of 8 groups of high dose vaccinated mice. Lower doses of vaccine showed a reduction of protection in a dose-dependent manner. However, even the lowest dose of vaccine provided significant levels of protection against the divergent influenza strains, especially considering the stringency of the challenge virus. In addition, we found that all doses of H5-Con vaccine were capable of providing complete protection against mortality when challenged with lethal doses of all 3 H5N1 influenza strains. This data demonstrates that centralized H1-Con, H3-Con and H5-Con genes can be effectively used to completely protect mice against many diverse strains of influenza. Therefore, we believe that these Ad-vectored centralized genes could be easily translated into new human vaccines.

  2. Pathogenicity and Transmission of H5 and H7 Highly Pathogenic Avian Influenza Viruses in Mallards

    Science.gov (United States)

    Costa-Hurtado, Mar; Shepherd, Eric; DeJesus, Eric; Smith, Diane; Spackman, Erica; Kapczynski, Darrell R.; Suarez, David L.; Stallknecht, David E.; Swayne, David E.

    2016-01-01

    ABSTRACT Wild aquatic birds have been associated with the intercontinental spread of H5 subtype highly pathogenic avian influenza (HPAI) viruses of the A/goose/Guangdong/1/96 (Gs/GD) lineage during 2005, 2010, and 2014, but dispersion by wild waterfowl has not been implicated with spread of other HPAI viruses. To better understand why Gs/GD H5 HPAI viruses infect and transmit more efficiently in waterfowl than other HPAI viruses, groups of mallard ducks were challenged with one of 14 different H5 and H7 HPAI viruses, including a Gs/GD lineage H5N1 (clade 2.2) virus from Mongolia, part of the 2005 dispersion, and the H5N8 and H5N2 index HPAI viruses (clade 2.3.4.4) from the United States, part of the 2014 dispersion. All virus-inoculated ducks and contact exposed ducks became infected and shed moderate to high titers of the viruses, with the exception that mallards were resistant to Ck/Pennsylvania/83 and Ck/Queretaro/95 H5N2 HPAI virus infection. Clinical signs were only observed in ducks challenged with the H5N1 2005 virus, which all died, and with the H5N8 and H5N2 2014 viruses, which had decreased weight gain and fever. These three viruses were also shed in higher titers by the ducks, which could facilitate virus transmission and spread. This study highlights the possible role of wild waterfowl in the spread of HPAI viruses. IMPORTANCE The spread of H5 subtype highly pathogenic avian influenza (HPAI) viruses of the Gs/GD lineage by migratory waterfowl is a serious concern for animal and public health. H5 and H7 HPAI viruses are considered to be adapted to gallinaceous species (chickens, turkeys, quail, etc.) and less likely to infect and transmit in wild ducks. In order to understand why this is different with certain Gs/GD lineage H5 HPAI viruses, we compared the pathogenicity and transmission of several H5 and H7 HPAI viruses from previous poultry outbreaks to Gs/GD lineage H5 viruses, including H5N1 (clade 2.2), H5N8 and H5N2 (clade 2.3.4.4) viruses, in

  3. Development of Hybrid pH sensor for long-term seawater pH monitoring.

    Science.gov (United States)

    Nakano, Y.; Egashira, T.; Miwa, T.; Kimoto, H.

    2016-02-01

    We have been developing the in situ pH sensor (Hybrid pH sensor: HpHS) for the long-term seawater pH monitoring. We are planning to provide the HpHS for researchers and environmental consultants for observation of the CCS (Carbon dioxide Capture and Storage) monitoring system, the coastal environment monitoring system (e.g. Blue Carbon) and ocean acidification. The HpHS has two types of pH sensors (i.e. potentiometric pH sensor and spectrophotometric pH sensor). The spectrophotometric pH sensor can measure pH correctly and stably, however it needs large power consumption and a lot of reagents in a long period of observation. The pH sensor used m-cresol purple (mCP) as an indicator of pH (Clayton and Byrne, 1993 and Liu et al., 2011). We can choose both coefficients before deployment. On the other hand, although the potentiometric pH sensor is low power consumption and high-speed response (within 10 seconds), drifts in the pH of the potentiometric measurements may possibly occur for a long-term observation. The HpHS can measure in situ pH correctly and stably combining advantage of both pH sensors. The HpHS consists of an aluminum pressure housing with optical cell (main unit) and an aluminum silicon-oil filled, pressure-compensated vessel containing pumps and valves (diaphragm pump and valve unit) and pressure-compensated reagents bags (pH indicator, pure water and Tris buffer or certified reference material: CRM) with an ability to resist water pressure to 3000m depth. The main unit holds system control boards, pump drivers, data storage (micro SD card), LED right source, photodiode, optical cell and pressure proof windows. The HpHS also has an aluminum pressure housing that holds a rechargeable lithium-ion battery or a lithium battery for the power supply (DC 24 V). The HpHS is correcting the value of the potentiometric pH sensor (measuring frequently) by the value of the spectrophotometric pH sensor (measuring less frequently). It is possible to calibrate in

  4. Photodisintegration of 3H and 3He

    International Nuclear Information System (INIS)

    Faul, D.D.

    1980-09-01

    The photoneutron cross sections for 3 H and 3 He have been measured from threshold to approx. 25 MeV with monoenergetic photons from the annihilation in flight of fast positrons at the LLL Electron-Positron Linear Accelerator facility. These reactions include the two-body breakup of 3 H and the three-body breakup of both 3 H and 3 He; these measurements for 3 H are the first to span the energy region across the peaks of the cross sections. An efficient BF 3 -tube-and-paraffin neutron detector and high-pressure gaseous samples of several moles each (the activity of the 3 H sample was approx. 200,000 Ci) were employed in these measurements. Measurements on 16 O and 2 H also were performed to verify the absolute cross-section scale. The results, when compared with each other and with results for the two-body breakup cross section for 3 He from the literature, show that the two-body breakup cross sections for 3 H and 3 He have nearly the same shape, but the one for 3 He lies lower in magnitude; the three-body breakup cross section for 3 He lies higher in magnitude and is broader in the peak region and also rises less sharply from threshold than that for 3 H; and these measured differences between the cross sections for the breakup modes largely compensate in their sum, so that the total photon absorption cross sections for 3 H and 3 He are nearly the same in both size and shape at energies near and above their peaks. Theoretical results from the literature disagree with the experimental results to a certain extent over the entire photon-energy region for which the photoneutron cross sections were measured. 50 figures, 7 tables

  5. Synthesizing multi-objective H2/H-infinity dynamic controller using evolutionary algorithms

    DEFF Research Database (Denmark)

    Pedersen, Gerulf; Langballe, A.S.; Wisniewski, Rafal

    This paper covers the design of an Evolutionary Algorithm (EA), which should be able to synthesize a mixed H2/H-infinity. It will be shown how a system can be expressed as Matrix Inequalities (MI) and these will then be used in the design of the EA. The main objective is to examine whether a mixed...... H2/H-infinity controller is feasible, and if so, how the optimal mixed controller might befound....

  6. Synthesizing mixed H2/H-infinity dynamic controller using evolutionary algorithms

    DEFF Research Database (Denmark)

    Pedersen, Gerulf; Langballe, A.S.; Wisniewski, Rafal

    2001-01-01

    This paper covers the design of an Evolutionary Algorithm (EA), which should be able to synthesize a mixed H2/H-infinity. It will be shown how a system can be expressed as Matrix Inequalities (MI) and these will then be used in the design of the EA. The main objective is to examine whether a mixed...... H2/H-infinity controller is feasible, and if so, how the optimal mixed controller might befound....

  7. Cotransport of H+, lactate, and H2O in porcine retinal pigment epithelial cells

    DEFF Research Database (Denmark)

    Hamann, Steffen; Kiilgaard, Jens Folke; la Cour, Morten

    2003-01-01

    ) for the H(+) and lactate fluxes. The data suggest that H(2)O is cotransported along with H(+) and lactate ions in MCT1 localized to the retinal membrane. The study emphasizes the importance of this cotransporter in the maintenance of water homeostasis and pH in the subretinal space of a mammalian tissue...... and supports our previous study performed by an invasive technique in an amphibian tissue....

  8. Double Harmonic Transmission (D.H.T.

    Directory of Open Access Journals (Sweden)

    Sava Ianici

    2006-10-01

    Full Text Available The paper presents the construction and functioning of a new type of harmonic drive named double harmonic transmission (D.H.T.. In the second part of this paper is presented the dynamic analysis of the double harmonic transmission, which is based on the results of the experimental researches on the D.H.T. This study of the stress status and the forces distribution is necessary for to determine the durability on the portant elements of the D.H.T.

  9. Solitons on H bonds in proteins

    DEFF Research Database (Denmark)

    d'Ovidio, F.; Bohr, H.G.; Lindgård, Per-Anker

    2003-01-01

    system shows that the solitons are spontaneously created and are stable and moving along the helix axis. A perturbation on one of the three H-bond lines forms solitons on the other H bonds as well. The robust solitary wave may explain very long-lived modes in the frequency range of 100 cm(-1) which...... are found in recent x-ray laser experiments. The dynamics parameters of the Toda lattice are in accordance with the usual Lennard-Jones parameters used for realistic H-bond potentials in proteins....

  10. H-mode study in CHS

    International Nuclear Information System (INIS)

    Toi, K.; Morisaki, T.; Sakakibara, S.

    1995-02-01

    In CHS rapid H-mode transition is observed in NBI heated deuterium and hydrogen plasmas without obvious isotope effect, when a net plasma current is ramped up to increase the external rotational transform. The H-mode of CHS has many similarities with those in tokamaks. Recent measurement with fast response Langmuir probes has revealed that the rapid change in floating potential occurs at the transition, but the change follows the formation of edge transport barrier. The presence of ι/2π = 1 surface near the edge and sawtooth crash triggered by internal modes may play an important role for determining the H-mode transition in CHS. (author)

  11. H2 molecules and the intercloud medium

    International Nuclear Information System (INIS)

    Hill, J.K.; Hollenbach, D.J.

    1976-01-01

    We discuss expected column of densities of H 2 in the intercloud medium and the possible use of molecules as indicators of intercloud physical conditions. We treat molecule formation by the H - process and on graphite grains and show that the Barlow-Silk hypothesis of a 1 eV semichemical hydrogen-graphite bond leads to a large enhancement of the intercloud molecule formation rate. Rotational excitation calculations are presented for both cloud and intercloud conditions which show, in agreement with Jura, that the presently observed optically thin H 2 absorption components are more likely to originate in cold clouds than in the intercloud medium

  12. Photodissociation of H2+ by a ruby laser with ion energy analysis of ejected H+

    International Nuclear Information System (INIS)

    Ozenne, J.B.; Pham, D.; Tadjeddine, M.; Durup, J.

    1974-01-01

    The kinetic energy released in the photodissociation of H 2 + by a ruby laser beam has been measured. The spectrum of the dissociation kinetic energy of H + +H shows several vibrational levels, and after deconvolution due to the energetic and angular resolution of the apparatus, gives a population of those vibrational levels, close to theoretical population [fr

  13. F. H. C h . J othmann , De Bijbel in de loop der eeuwen. Kampen, J ...

    African Journals Online (AJOL)

    Test

    F. H. C h . J othmann , De Bijbel in de loop der eeuwen. Kampen, J . H. Kok. N.V., 1954, 43 bis. Prys 95 cent. Hierdie werkie geskryf vir gebruik op skool, kategesasie en jeug- vereniging is besonder smakelik versorg met uiters insiggewende illu- strasies oor die geskiedenis van die Bybel as geskrif en boek. Die stof is.

  14. Interactions of Heterodera daverti, H. goldeni and H. zeae with Meloidogyne incognita on rice

    Science.gov (United States)

    The interactions of the cyst nematodes Heterodera daverti, H. goldeni and H. zeae with the root-knot nematode Meloidogyne incognita on rice (Oryza sativa) cultivars Giza 178 and Sakha 101 were studied in the greenhouse. Inoculation with H. goldeni alone or one week before inoculation with M. incogni...

  15. The synthesis of [2-3H2] taurine and [2-3H2] hypotaurine

    International Nuclear Information System (INIS)

    Fellman, J.H.

    1981-01-01

    The synthesis of [2- 3 H 2 ]-2-aminoethanesulfonate [2- 3 H]-taurine by the reduction of cyanomethanesulfonic acid with tritium gas is described. The conversion of [2- 3 H]-taurine and its 14 C and 35 S isotopic forms to 2-aminoethanesulfinate (hypotaurine) was accomplished by converting taurine to its corresponding sulfonyl chloride and reducing the latter with metallic zinc. (author)

  16. Civilsamfundets ABC: H for Høflighed

    DEFF Research Database (Denmark)

    Lund, Anker Brink; Meyer, Gitte

    2016-01-01

    Vi er nået til H for Høflighed. At være høflig er det samme som at være hof-lig. Tager man begrebet umiddelbart på ordet, drejer det sig altså om at opføre sig, som det sømmer sig ved hoffet, blandt de fornemme.......Vi er nået til H for Høflighed. At være høflig er det samme som at være hof-lig. Tager man begrebet umiddelbart på ordet, drejer det sig altså om at opføre sig, som det sømmer sig ved hoffet, blandt de fornemme....

  17. D/H ratio for Jupiter

    International Nuclear Information System (INIS)

    Smith, H.; Schempp, W.V.; Baines, K.H.

    1989-01-01

    Observations of Jupiter's spectrum near the R5(0) HD line at 6063.88 A are reported. A feature with an equivalent width of 0.065 + or - 0.021 mA is coincident with the expected line. This feature is compared with HD profiles computed for inhomogeneous scattering models for Jupiter to yield a range for the Jovian D/H ratio of 1.0-2.9 x 10 to the -5th. This D/H ratio is in the lower range of previously reported D/H values for Jupiter and corresponds to an essentially solar D/H ratio for Jupiter. The detection of HD features in the presence of probable blends with spectral features of minor atmospheric hydrocarbon molecules is discussed. Such blends may make unambiguous identification of HD features difficult. 26 references

  18. 183-H Basin sludge treatability test report

    International Nuclear Information System (INIS)

    Biyani, R.K.

    1995-01-01

    This document presents the results from the treatability testing of a 1-kg sample of 183-H Basin sludge. Compressive strength measurements, Toxic Characteristic Leach Procedure, and a modified ANSI 16.1 leach test were conducted

  19. Constraints on H(0) from globular clusters

    International Nuclear Information System (INIS)

    Vandenberg, D.A.

    1988-01-01

    On the basis of canonical stellar evolutionary computations, the maximum age of the globular clusters is suggested to be near either 14 Gyr or 18 Gyr, depending on how (O/Fe) varies with (Fe/H) in the cluster stars. The lower estimate requires that H(0) = 65 km/s/Mpc or less, for all Omega(0) = O or greater, if the standard Big-Bang cosmological theory is correct - while the higher age value similarly constrains the Hubble constant to be smaller than 46 km/s/Mpc. Some reduction in the upper limit to cluster ages and a consequent increase in H(0) may be expected if helium diffusion is important in Population II stars; nevertheless, values of H(0) greater than 75 km/s/Mpc still appear to be precluded unless the cosmological constant is nonzero. 51 refs

  20. Gravitational instantons in H-spaces

    International Nuclear Information System (INIS)

    Hacyan, S.

    1979-01-01

    A spin coefficient method valid for spaces with positive definite metric is presented, together with a Petrov-Penrosetype classification. The theory of H-spaces is applied to self-dual gravitational instantons. (orig.)

  1. hCG Test (Pregnancy Test)

    Science.gov (United States)

    ... Acidosis and Alkalosis Adrenal Insufficiency and Addison Disease Alcoholism Allergies Alzheimer Disease Anemia Angina Ankylosing Spondylitis Anthrax ... Patient Resources For Health Professionals Subscribe Search hCG Pregnancy Send Us Your Feedback Choose Topic At a ...

  2. Sensing H+ with conventional neural probes

    International Nuclear Information System (INIS)

    Trantidou, T.; Tsiligkiridis, V.; Chang, Y.-C.; Toumazou, C.; Prodromakis, T.

    2013-01-01

    In this paper, we demonstrate a technique for transforming commercially available neural probes used for electrical recordings, into chemical sensing devices for detection of ionic concentrations in electrolytes, with particular emphasis to pH. This transformation requires a single post-processing step to incorporate a thin indium tin oxide membrane for sensing H + . Measured results indicate a chemical sensitivity of 28 mV/pH, and relatively low leakage currents (2–10 nA) and drifts (1–10 mV/h). The proposed sensing device demonstrates the possibility of a low-cost implementation that can be reusable and thus versatile, with potential applications in real-time extracellular but mainly intracellular chemical monitoring.

  3. Solar Imagery - Chromosphere - H-Alpha

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Collection includes a variety of H-alpha photographic datasets contributed by a number of national and private solar observatories located worldwide. Solar...

  4. Report of Committee H. Liquefied gases

    International Nuclear Information System (INIS)

    Miyata, Yoshiaki

    1997-01-01

    Committee H covers liquefied gases, both liquefied natural gas (LNG) and liquefied petroleum gas (LPG). In this triennium (1994-1997), Subcommittee H-1 and H-2 carried out a general survey of LNG and LPG respectively including supply and demand, world LNG trade, LPG production facilities, LNG liquefaction plants, LNG schemes existing or under construction and future projects. Additionally five working groups were set up to cover the following work items selected from among major topics that the liquefied gas industries are facing or concerned with. The topics for LNG are ''Operational aspects of liquefaction plants'', ''Cost reduction of LNG chains'', ''Evolution of major cryogenic equipment'' and those for LPG are ''New developments in future LPG utilization'' and ''LPG: An optimal fuel for developing countries''. It should be noted that, in addition to traditional surveys, Committee H also tried making a cost analysis of LNG chains for the first time, in ''Cost reduction of LNG chains''. (au)

  5. Histone H2AX in DNA repair

    International Nuclear Information System (INIS)

    Lewandowska, H.; Szumiel, I.

    2002-01-01

    The paper reviews the recent reports on the role of the phosphorylated histone H2AX (γ-H2AX). The modification of this histone is an important part of the cellular response to the induction of DNA double strand brakes (DSB) by ionising radiation and other DSB-generating factors. In irradiated cells the modification is carried out mainly by ATM (ataxia-telangiectasia mutated) kinase, the enzyme that starts the alarm signalling upon induction of DSB.γ-H2AX molecules are formed within 1-3 min after irradiation and form foci at the sites of DSB. This seems to be necessary for the recruitment of repair factors that are later present in foci of damaged nuclei. Modification of a constant percentage of H2AX molecules per DSB takes place, corresponding to chromatin domains of megabase of DNA. (author)

  6. Partial cross sections in H- photodetachment

    International Nuclear Information System (INIS)

    Halka, M.

    1993-04-01

    This dissertation reports experimental measurements of partial decay cross sections in the H - photodetachment spectrum. Observed decays of the 1 P 0 H -** (n) doubly-excitedresonances to the H(N=2) continuum are reported for n=2,3, and 4 from 1990 runs in which the author participated. A recent analysis of 1989 data revealing effects of static electric fields on the partial decay spectrum above 13.5 eV is also presented. The experiments were performed at the High Resolution Atomic Beam Facility. the Los Alamos Meson Physics Facility, with a relativistic H - beam (β=0.842)intersecting a ND:YAG laser. Variation of the intersection angle amounts to Doppler-shifting the photon energy, allowing continuous tuning of the laser energy as viewed from the moving ions' frame

  7. Inglismaal hävitatakse fotoraamatuid

    Index Scriptorium Estoniae

    1998-01-01

    Mapplethorpe'i fotoraamatute konfiskeerimisest Birminghami Ülikooli raamatukogust Birminghami politsei poolt. Politsei on teinud avalduse kirjastusele Random House'ile, et hävitada veel laos olevad fotoalbumid

  8. Environmental Chemistry Methods (ECM) Index - H

    Science.gov (United States)

    Laboratories use testing methods to identify pesticides in water and soil. Environmental chemistry methods test soil and water samples to determine the fate of pesticides in the environment. Find methods for chemicals with H as the first character.

  9. Co-H-spaces and almost localization

    OpenAIRE

    Costoya, Cristina; Iwase, Norio

    2012-01-01

    Apart from simply-connected spaces, a non simply-connected co-H-space is a typical example of a space X with a co-action of $B\\pi_1(X)$ along $r^X : X \\rightarrow B\\pi_{1}(X)$ the classifying map of the universal covering. If such a space X is actually a co-H-space, then the fibrewise p-localization of $r^X$ (or the `almost' p-localization of X) is a fibrewise co-H-space (or an `almost' co-H-space, resp.) for every prime p. In this paper, we show that the converse statement is true, i.e., for...

  10. High efficiency beam splitting for H- accelerators

    International Nuclear Information System (INIS)

    Kramer, S.L.; Stipp, V.; Krieger, C.; Madsen, J.

    1985-01-01

    Beam splitting for high energy accelerators has typically involved a significant loss of beam and radiation. This paper reports on a new method of splitting beams for H - accelerators. This technique uses a high intensity flash of light to strip a fraction of the H - beam to H 0 which are then easily separated by a small bending magnet. A system using a 900-watt (average electrical power) flashlamp and a highly efficient collector will provide 10 -3 to 10 -2 splitting of a 50 MeV H - beam. Results on the operation and comparisons with stripping cross sections are presented. Also discussed is the possibility for developing this system to yield a higher stripping fraction

  11. Salivary pH: A diagnostic biomarker

    OpenAIRE

    Baliga, Sharmila; Muglikar, Sangeeta; Kale, Rahul

    2013-01-01

    Objectives: Saliva contains a variety of host defense factors. It influences calculus formation and periodontal disease. Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease. With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test. The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease. Study D...

  12. Financing exponential growth at H3

    OpenAIRE

    Silva, João Ricardo Ferreira Hipolito da

    2012-01-01

    H3 is a fast-food chain that introduced the concept of gourmet hamburgers in the Portuguese market. This case-study illustrates its financing strategy that supported an exponential growth represented by opening 33 restaurants within approximately 3 years of its inception. H3 is now faced with the challenge of structuring its foreign ventures and change its financial approach. The main covered topics are the options an entrepreneur has for financing a new venture and how it evolves along th...

  13. The status of DESY H- - sources

    International Nuclear Information System (INIS)

    Peters, J.

    1996-01-01

    Two different types of H - sources are operated at DESY, a magnetron source and an rf- driven volume source. H - sources for HERA have to run for long uninterrupted periods with a low duty factor and a high reliability. Several necessary improvements are under construction for our rf - driven volume source. The status of both our magnetron and our volume source will be discussed and the first LINAC III experiment with the rf-driven volume source will be presented. (author)

  14. Limiter H-mode experiments on TFTR

    Energy Technology Data Exchange (ETDEWEB)

    Bush, C [Oak Ridge National Lab., TN (USA); Bretz, N L; Fredrickson, E D; McGuire, K M; Nazikian, R; Park, H K; Schivell, J; Taylor, G; Bitter, B; Budny, R; Cohen, S A; Kilpatrick, S J; LeBlanc, B; Manos, D M; Meade, D; Paul, S F; Scott, S D; Stratton, B C; Synakowski, E J; Towner, H H; Weiland, R M; Arunasalam, V; Bateman, G; Bell, M G; Bell, R; Boivin, R; Cavallo, A; Cheng, C Z; Chu, T K; Cowl,

    1990-12-15

    Limiter H-modes with centrally peaked density profiles have been obtained in TFTR using a highly conditioned graphite limiter. The transition to these centrally peaked H-modes takes place from the supershot to the H-mode rather than the usual L- to H-mode transition observed on other tokamaks. Bi-directional beam heating is required to induce the transition. Density peaking factors, n{sub e}(0)/{l angle}n{sub e}{r angle}, >2.3 are obtained and at the same time the H-mode characteristics are similar to those of limiter H-modes on other tokamaks and the global confinement, {tau}{sub E}, can be >2.5 times L-mode scaling. The TRANSP analysis shows that transport in these H-modes is similar to that of supershots within the inner 60 cm of the plasma, but the stored electron energy (calculated using measured values of T{sub e} and n{sub e}) is higher for the H-mode at the plasma edge. Microwave scattering near the edge shows broad spectra at k = 5.5 cm{sup {minus}1} which begin at the drop in D{sub {alpha}} radiation and are strongly shifted in the electron diamagnetic drift direction. At the same time beam emission spectroscopy shows a coherent mode near the boundary with m = 15--20 at 20--30 kHz which is propagating in the ion direction. During an ELM event these apparent rotations cease and Mirnov fluctuations in the 50--500 kHz increase in intensity.

  15. 4-H NFPA Fluid Power Challenge

    OpenAIRE

    Bonnett, Erika D

    2016-01-01

    The 4-H NFPA Fluid Power Challenge partnered Purdue Polytechnic Institute and Indiana 4-H with the National Fluid Power Association and Center for Compact and Efficient Fluid Power to provide teams of Indiana youth in 6-8th grades with opportunity to learn about hydraulics, engineering design, and other STEM skills. This created an opportunity to give youth a learning experience with STEM through hands-on, experiential learning activities. Youth experienced a one day workshop in which they wo...

  16. The symbiotic star H1-36

    International Nuclear Information System (INIS)

    Allen, D.A.

    1983-01-01

    Optical and infrared spectrophotometry is presented of the high-excitation emission-line star H1-36. The presence of a variable M giant is established: H1-36 may therefore be classified as a symbiotic star. The observations are interpreted in terms of the usual binary model for symbiotic stars, namely that an unseen star is heated by accretion of gas from its companion M giant. (author)

  17. Hyperpolarized H2O MR angiography

    DEFF Research Database (Denmark)

    Ardenkjær-Larsen, Jan Henrik; Laustsen, Christoffer; Bowen, Sean

    2014-01-01

    polarization followed by dissolution in D2O. A water 1H signal enhancement of 77 times compared with 4.7 Tesla was obtained. This corresponds to a polarization of 3.5% for the 3.9 mol/L 1H in D2O . Moreover, a T1 in excess of 20 s was achieved. The use of hyperpolarized water as a contrast agent presents a new...

  18. The H-mode operational window as determined from the ITER H-mode database

    International Nuclear Information System (INIS)

    Ryter, F.; Kardaun, O.J.W.F.; Stroth, U.

    1994-01-01

    The H-mode is a promising regime for fusion reactors and it is essential to be able to predict its operational window in future devices. The 'H-Mode Database Working Group' started in 1992 to gather, analyze and compare H-mode threshold data from several divertor tokamaks so that predictions could be made. The database and first results were presented and the threshold database has been improved and extended since. The work has two objectives: 1) to predict the minimum heating power necessary to reach the H-mode in future devices, 2) to contribute to physics studies of the L-H transition. (author) 11 refs., 2 figs

  19. 2-(4-Fluorophenyl-2H-chromen-4(3H-one

    Directory of Open Access Journals (Sweden)

    Michał Wera

    2012-02-01

    Full Text Available In the crystal structure of the title compound, C15H11FO2, molecules form inversion dimers through pairs of weak C—H...O hydrogen bonds. Dimers oriented in parallel, linked by C—H...π contacts, are arranged in columns along the b axis. The fluorophenyl ring and the benzene ring of the 2H-chromen-4(3H-one unit are inclined to one another by 70.41 (16°. They are respectively parallel in a given column or almost perpendicular [oriented at an angle of 87.8 (1°] in neighbouring (inversely oriented columns, forming a herringbone pattern.

  20. pH-Taxis of Biohybrid Microsystems

    Science.gov (United States)

    Zhuang, Jiang; Wright Carlsen, Rika; Sitti, Metin

    2015-06-01

    The last decade has seen an increasing number of studies developing bacteria and other cell-integrated biohybrid microsystems. However, the highly stochastic motion of these microsystems severely limits their potential use. Here, we present a method that exploits the pH sensing of flagellated bacteria to realize robust drift control of multi-bacteria propelled microrobots. Under three specifically configured pH gradients, we demonstrate that the microrobots exhibit both unidirectional and bidirectional pH-tactic behaviors, which are also observed in free-swimming bacteria. From trajectory analysis, we find that the swimming direction and speed biases are two major factors that contribute to their tactic drift motion. The motion analysis of microrobots also sheds light on the propulsion dynamics of the flagellated bacteria as bioactuators. It is expected that similar driving mechanisms are shared among pH-taxis, chemotaxis, and thermotaxis. By identifying the mechanism that drives the tactic behavior of bacteria-propelled microsystems, this study opens up an avenue towards improving the control of biohybrid microsystems. Furthermore, assuming that it is possible to tune the preferred pH of bioactuators by genetic engineering, these biohybrid microsystems could potentially be applied to sense the pH gradient induced by cancerous cells in stagnant fluids inside human body and realize targeted drug delivery.