WorldWideScience

Sample records for hybrid sampling plan

  1. Landmarks in Hybrid Planning

    Directory of Open Access Journals (Sweden)

    Mohamed Elkawkagy

    2013-11-01

    Full Text Available Although planning techniques achieved a significant progress during recent years, solving many planning problem still difficult even for modern planners. In this paper, we will adopt landmark concept to hybrid planning setting - a method that combines reasoning about procedural knowledge and causalities. Land-marks are a well-known concept in the realm of classical planning. Recently, they have been adapted to hierarchical approaches. Such landmarks can be extracted in a pre-processing step from a declarative hierarchical planning domain and problem description. It was shown how this technique allows for a considerable reduction of the search space by eliminating futile plan development options before the actual planning. Therefore, we will present a new approach to in¬tegrate landmark pre-processing technique in the context of hierarchical planning with landmark technique in the classical planning. This integration allows to incorporate the ability of using extracted landmark tasks from hierarchical domain knowledge in the form of HTN and using landmark literals from classical planning. To this end, we will construct a transformation technique to transform the hybrid planning domain into a classical domain model. The method¬ologies in this paper have been implemented successfully, and we will present some experimental results that give evidence for the consid-erable performance increase gained through planning system.

  2. Visual Sample Plan

    Energy Technology Data Exchange (ETDEWEB)

    2007-10-25

    VSP selects the appropriate number and location of environmental samples to ensure that the results of statistical tests performed to provide input to risk decisions have the required confidence and performance. VSP Version 5.0 provides sample-size equations or algorithms needed by specific statistical tests appropriate for specific environmental sampling objectives. It also provides data quality assessment and statistical analysis functions to support evaluation of the data and determine whether the data support decisions regarding sites suspected of contamination. The easy-to-use program is highly visual and graphic. VSP runs on personal computers with Microsoft Windows operating systems (98, NT, 2000, Millennium Edition, CE, and XP) Designed primarily for project managers and users without expertise in statistics, VSP is applicable to two- and three-dimensional populations to be sampled (e.g., rooms and buildings, surface soil, a defined layer of subsurface soil, water bodies, and other similar applications) for studies of environmental quality. VSP is also applicable for designing sampling plans for assessing chem./rad/bio threat and hazard identification within rooms and buildings, and for designing geophysical surveys for UXO identification.

  3. Lake Ladora sampling plan, 1993

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Task plan from the U.S. Geological Survey for sampling Lake Ladora on the Rocky Mountain National Wildlife Refuge. During the review of the FY93 Surface-Water...

  4. 75 FR 64123 - Hybrid Retirement Plans

    Science.gov (United States)

    2010-10-19

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BG36 Hybrid Retirement Plans AGENCY: Internal Revenue... defined benefit pension plans. These regulations provide guidance on changes made by the Pension... plans. DATES: Effective Date: These regulations are effective on October 19, 2010. Applicability Date...

  5. Motion Planning via Manifold Samples

    CERN Document Server

    Salzman, Oren; Raveh, Barak; Halperin, Dan

    2011-01-01

    We present a general and modular algorithmic framework for path planning of robots. Our framework combines geometric methods for exact and complete analysis of low-dimensional configuration spaces, together with practical, considerably simpler sampling-based approaches that are appropriate for higher dimensions. In order to facilitate the transfer of advanced geometric algorithms into practical use, we suggest taking samples that are entire low-dimensional manifolds of the configuration space that capture the connectivity of the configuration space much better than isolated point samples. Geometric algorithms for analysis of low-dimensional manifolds then provide powerful primitive operations. The modular design of the framework enables independent optimization of each modular component. Indeed, we have developed, implemented and optimized a primitive operation for complete and exact combinatorial analysis of a certain set of manifolds, using arrangements of curves of rational functions and concepts of generi...

  6. 76 FR 4244 - Hybrid Retirement Plans

    Science.gov (United States)

    2011-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 RIN 1545-BG36 Hybrid Retirement Plans Correction In rule document 2010-25941 beginning on page 64123 in the issue of Tuesday, October 19, 2010, make the following...

  7. 76 FR 67105 - Cash Balance Plans; Benefit Determinations and Plan Valuations for Statutory Hybrid Plans...

    Science.gov (United States)

    2011-10-31

    ... would apply to all statutory hybrid plans. If a cash balance plan uses a fixed interest rate as of the..., however, when a cash balance plan uses a variable interest rate--e.g., a rate that changes annually under... CORPORATION 29 CFR Parts 4001, 4022, 4041, and 4044 RIN 1212-AB17 Cash Balance Plans; Benefit...

  8. Adopting hybrid pension plans: financial and communication issues.

    Science.gov (United States)

    Clark, R L; Haley, J J; Schieber, S J

    2001-01-01

    This article provides a systematic framework for the evaluation of the movement toward hybrid pension plans by examining the reasons given by firms for converting their existing pension plans to hybrid plans, illustrating the impact of plan changes on expected pension benefits, and identifying winners and losers.

  9. Plug-in hybrid electric vehicle R&D plan

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2007-06-01

    FCVT, in consultation with industry and other appropriate DOE offices, developed the Draft Plug-In Hybrid Electric Vehicle R&D Plan to accelerate the development and deployment of technologies critical for plug-in hybrid vehicles.

  10. Emperical Tests of Acceptance Sampling Plans

    Science.gov (United States)

    White, K. Preston, Jr.; Johnson, Kenneth L.

    2012-01-01

    Acceptance sampling is a quality control procedure applied as an alternative to 100% inspection. A random sample of items is drawn from a lot to determine the fraction of items which have a required quality characteristic. Both the number of items to be inspected and the criterion for determining conformance of the lot to the requirement are given by an appropriate sampling plan with specified risks of Type I and Type II sampling errors. In this paper, we present the results of empirical tests of the accuracy of selected sampling plans reported in the literature. These plans are for measureable quality characteristics which are known have either binomial, exponential, normal, gamma, Weibull, inverse Gaussian, or Poisson distributions. In the main, results support the accepted wisdom that variables acceptance plans are superior to attributes (binomial) acceptance plans, in the sense that these provide comparable protection against risks at reduced sampling cost. For the Gaussian and Weibull plans, however, there are ranges of the shape parameters for which the required sample sizes are in fact larger than the corresponding attributes plans, dramatically so for instances of large skew. Tests further confirm that the published inverse-Gaussian (IG) plan is flawed, as reported by White and Johnson (2011).

  11. Nitrate Waste Treatment Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    Vigil-Holterman, Luciana R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Martinez, Patrick Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Garcia, Terrence Kerwin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-05

    This plan is designed to outline the collection and analysis of nitrate salt-bearing waste samples required by the New Mexico Environment Department- Hazardous Waste Bureau in the Los Alamos National Laboratory (LANL) Hazardous Waste Facility Permit (Permit).

  12. Sample size planning for classification models.

    Science.gov (United States)

    Beleites, Claudia; Neugebauer, Ute; Bocklitz, Thomas; Krafft, Christoph; Popp, Jürgen

    2013-01-14

    In biospectroscopy, suitably annotated and statistically independent samples (e.g. patients, batches, etc.) for classifier training and testing are scarce and costly. Learning curves show the model performance as function of the training sample size and can help to determine the sample size needed to train good classifiers. However, building a good model is actually not enough: the performance must also be proven. We discuss learning curves for typical small sample size situations with 5-25 independent samples per class. Although the classification models achieve acceptable performance, the learning curve can be completely masked by the random testing uncertainty due to the equally limited test sample size. In consequence, we determine test sample sizes necessary to achieve reasonable precision in the validation and find that 75-100 samples will usually be needed to test a good but not perfect classifier. Such a data set will then allow refined sample size planning on the basis of the achieved performance. We also demonstrate how to calculate necessary sample sizes in order to show the superiority of one classifier over another: this often requires hundreds of statistically independent test samples or is even theoretically impossible. We demonstrate our findings with a data set of ca. 2550 Raman spectra of single cells (five classes: erythrocytes, leukocytes and three tumour cell lines BT-20, MCF-7 and OCI-AML3) as well as by an extensive simulation that allows precise determination of the actual performance of the models in question. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Acceptance sampling reliability test plans for alpha distributed lifetime

    OpenAIRE

    Khan, Maroof A.; Islam, H. M.

    2013-01-01

    Determining the acceptability of any product, reliability sampling plans are used. In this paper, reliability sampling plans for truncated life test are developed when the lifetimes of a test follow an alpha distribution. The sampling plan proposed here can save the test time in practical situations. Sampling plans are established through an algorithm. Moreover, some tables are provided for the proposed sampling plans so that proposed method can be used conveniently for the practitioner. Oper...

  14. Visual Sample Plan (VSP) - FIELDS Integration

    Energy Technology Data Exchange (ETDEWEB)

    Pulsipher, Brent A.; Wilson, John E.; Gilbert, Richard O.; Hassig, Nancy L.; Carlson, Deborah K.; Bing-Canar, John; Cooper, Brian; Roth, Chuck

    2003-04-19

    Two software packages, VSP 2.1 and FIELDS 3.5, are being used by environmental scientists to plan the number and type of samples required to meet project objectives, display those samples on maps, query a database of past sample results, produce spatial models of the data, and analyze the data in order to arrive at defensible decisions. VSP 2.0 is an interactive tool to calculate optimal sample size and optimal sample location based on user goals, risk tolerance, and variability in the environment and in lab methods. FIELDS 3.0 is a set of tools to explore the sample results in a variety of ways to make defensible decisions with quantified levels of risk and uncertainty. However, FIELDS 3.0 has a small sample design module. VSP 2.0, on the other hand, has over 20 sampling goals, allowing the user to input site-specific assumptions such as non-normality of sample results, separate variability between field and laboratory measurements, make two-sample comparisons, perform confidence interval estimation, use sequential search sampling methods, and much more. Over 1,000 copies of VSP are in use today. FIELDS is used in nine of the ten U.S. EPA regions, by state regulatory agencies, and most recently by several international countries. Both software packages have been peer-reviewed, enjoy broad usage, and have been accepted by regulatory agencies as well as site project managers as key tools to help collect data and make environmental cleanup decisions. Recently, the two software packages were integrated, allowing the user to take advantage of the many design options of VSP, and the analysis and modeling options of FIELDS. The transition between the two is simple for the user – VSP can be called from within FIELDS, automatically passing a map to VSP and automatically retrieving sample locations and design information when the user returns to FIELDS. This paper will describe the integration, give a demonstration of the integrated package, and give users download

  15. A Hybrid 3D Path Planning Method for UAVs

    DEFF Research Database (Denmark)

    Ortiz-Arroyo, Daniel

    2015-01-01

    This paper presents a hybrid method for path planning in 3D spaces. We propose an improvement to a near-optimal 2D off-line algorithm and a flexible normalized on-line fuzzy controller to find shortest paths. Our method, targeted to low altitude domains, is simple and efficient. Our preliminary resu...

  16. Effect of sample storage time on detection of hybridization signals in Checkerboard DNA-DNA hybridization.

    Science.gov (United States)

    do Nascimento, Cássio; Muller, Katia; Sato, Sandra; Albuquerque Junior, Rubens Ferreira

    2012-04-01

    Long-term sample storage can affect the intensity of the hybridization signals provided by molecular diagnostic methods that use chemiluminescent detection. The aim of this study was to evaluate the effect of different storage times on the hybridization signals of 13 bacterial species detected by the Checkerboard DNA-DNA hybridization method using whole-genomic DNA probes. Ninety-six subgingival biofilm samples were collected from 36 healthy subjects, and the intensity of hybridization signals was evaluated at 4 different time periods: (1) immediately after collecting (n = 24) and (2) after storage at -20 °C for 6 months (n = 24), (3) for 12 months (n = 24), and (4) for 24 months (n = 24). The intensity of hybridization signals obtained from groups 1 and 2 were significantly higher than in the other groups (p  0.05). The Checkerboard DNA-DNA hybridization method was suitable to detect hybridization signals from all groups evaluated, and the intensity of signals decreased significantly after long periods of sample storage.

  17. Heat-capacity measurements on small samples: The hybrid method

    NARCIS (Netherlands)

    Klaasse, J.C.P.; Brück, E.H.

    2008-01-01

    A newly developed method is presented for measuring heat capacities on small samples, particularly where thermal isolation is not sufficient for the use of the traditional semiadiabatic heat-pulse technique. This "hybrid technique" is a modification of this heat-pulse method in case the temperature

  18. Heat-capacity measurements on small samples: The hybrid method

    NARCIS (Netherlands)

    Klaasse, J.C.P.; Brück, E.H.

    2008-01-01

    A newly developed method is presented for measuring heat capacities on small samples, particularly where thermal isolation is not sufficient for the use of the traditional semiadiabatic heat-pulse technique. This "hybrid technique" is a modification of this heat-pulse method in case the temperature

  19. Advanced Hybrid Particulate Collector Project Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Miller, S.J.

    1995-11-01

    As the consumption of energy increases, its impact on ambient air quality has become a significant concern. Recent studies indicate that fine particles from coal combustion cause health problems as well as atmospheric visibility impairment. These problems are further compounded by the concentration of hazardous trace elements such as mercury, cadmium, selenium, and arsenic in fine particles. Therefore, a current need exists to develop superior, but economical, methods to control emissions of fine particles. Since most of the toxic metals present in coal will be in particulate form, a high level of fine- particle collection appears to be the best method of overall air toxics control. However, over 50% of mercury and a portion of selenium emissions are in vapor form and cannot be collected in particulate control devices. Therefore, this project will focus on developing technology not only to provide ultrahigh collection efficiency of particulate air toxic emissions, but also to capture vapor- phase trace metals such as mercury and selenium. Currently, the primary state-of-the-art technologies for particulate control are fabric filters (baghouses) and electrostatic precipitators (ESPs). However, they both have limitations that prevent them from achieving ultrahigh collection of fine particulate matter and vapor-phase trace metals. The objective of this project is to develop a highly reliable advanced hybrid particulate collector (AHPC) that can provide > 99.99 % particulate collection efficiency for all particle sizes between 0.01 and 50 14m, is applicable for use with all U.S. coals, and is cost-0443competitive with existing technologies. Phase I of the project is organized into three tasks: Task I - Project Management, Reporting, and Subcontract Consulting Task 2 - Modeling, Design, and Construction of 200-acfm AHPC Model Task 3 - Experimental Testing and Subcontract Consulting

  20. ANALYSING ACCEPTANCE SAMPLING PLANS BY MARKOV CHAINS

    Directory of Open Access Journals (Sweden)

    Mohammad Mirabi

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: In this research, a Markov analysis of acceptance sampling plans in a single stage and in two stages is proposed, based on the quality of the items inspected. In a stage of this policy, if the number of defective items in a sample of inspected items is more than the upper threshold, the batch is rejected. However, the batch is accepted if the number of defective items is less than the lower threshold. Nonetheless, when the number of defective items falls between the upper and lower thresholds, the decision-making process continues to inspect the items and collect further samples. The primary objective is to determine the optimal values of the upper and lower thresholds using a Markov process to minimise the total cost associated with a batch acceptance policy. A solution method is presented, along with a numerical demonstration of the application of the proposed methodology.

    AFRIKAANSE OPSOMMING: In hierdie navorsing word ’n Markov-ontleding gedoen van aannamemonsternemingsplanne wat plaasvind in ’n enkele stap of in twee stappe na gelang van die kwaliteit van die items wat geïnspekteer word. Indien die eerste monster toon dat die aantal defektiewe items ’n boonste grens oorskry, word die lot afgekeur. Indien die eerste monster toon dat die aantal defektiewe items minder is as ’n onderste grens, word die lot aanvaar. Indien die eerste monster toon dat die aantal defektiewe items in die gebied tussen die boonste en onderste grense lê, word die besluitnemingsproses voortgesit en verdere monsters word geneem. Die primêre doel is om die optimale waardes van die booonste en onderste grense te bepaal deur gebruik te maak van ’n Markov-proses sodat die totale koste verbonde aan die proses geminimiseer kan word. ’n Oplossing word daarna voorgehou tesame met ’n numeriese voorbeeld van die toepassing van die voorgestelde oplossing.

  1. Long-Term Ecological Monitoring Field Sampling Plan for 2007

    Energy Technology Data Exchange (ETDEWEB)

    T. Haney

    2007-07-31

    This field sampling plan describes the field investigations planned for the Long-Term Ecological Monitoring Project at the Idaho National Laboratory Site in 2007. This plan and the Quality Assurance Project Plan for Waste Area Groups 1, 2, 3, 4, 5, 6, 7, 10, and Removal Actions constitute the sampling and analysis plan supporting long-term ecological monitoring sampling in 2007. The data collected under this plan will become part of the long-term ecological monitoring data set that is being collected annually. The data will be used t determine the requirements for the subsequent long-term ecological monitoring. This plan guides the 2007 investigations, including sampling, quality assurance, quality control, analytical procedures, and data management. As such, this plan will help to ensure that the resulting monitoring data will be scientifically valid, defensible, and of known and acceptable quality.

  2. Hybrid control and motion planning of dynamical legged locomotion

    CERN Document Server

    2012-01-01

    "This book provides a comprehensive presentation of issues and challenges faced by researchers and practicing engineers in motion planning and hybrid control of dynamical legged locomotion. The major features range from offline and online motion planning algorithms to generate desired feasible periodic walking and running motions and tow-level control schemes, including within-stride feedback laws, continuous time update laws and event-based update laws, to asymptotically stabilize the generated desired periodic orbits. This book describes the current state of the art and future directions across all domains of dynamical legged locomotion so that readers can extend proposed motion planning algorithms and control methodologies to other types of planar and 3D legged robots".

  3. Short-Term Planning of Hybrid Power System

    Science.gov (United States)

    Knežević, Goran; Baus, Zoran; Nikolovski, Srete

    2016-07-01

    In this paper short-term planning algorithm for hybrid power system consist of different types of cascade hydropower plants (run-of-the river, pumped storage, conventional), thermal power plants (coal-fired power plants, combined cycle gas-fired power plants) and wind farms is presented. The optimization process provides a joint bid of the hybrid system, and thus making the operation schedule of hydro and thermal power plants, the operation condition of pumped-storage hydropower plants with the aim of maximizing profits on day ahead market, according to expected hourly electricity prices, the expected local water inflow in certain hydropower plants, and the expected production of electrical energy from the wind farm, taking into account previously contracted bilateral agreement for electricity generation. Optimization process is formulated as hourly-discretized mixed integer linear optimization problem. Optimization model is applied on the case study in order to show general features of the developed model.

  4. Nevada National Security Site Integrated Groundwater Sampling Plan, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Marutzky, Sam; Farnham, Irene

    2014-10-01

    The purpose of the Nevada National Security Site (NNSS) Integrated Sampling Plan (referred to herein as the Plan) is to provide a comprehensive, integrated approach for collecting and analyzing groundwater samples to meet the needs and objectives of the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) Underground Test Area (UGTA) Activity. Implementation of this Plan will provide high-quality data required by the UGTA Activity for ensuring public protection in an efficient and cost-effective manner. The Plan is designed to ensure compliance with the UGTA Quality Assurance Plan (QAP). The Plan’s scope comprises sample collection and analysis requirements relevant to assessing the extent of groundwater contamination from underground nuclear testing. This Plan identifies locations to be sampled by corrective action unit (CAU) and location type, sampling frequencies, sample collection methodologies, and the constituents to be analyzed. In addition, the Plan defines data collection criteria such as well-purging requirements, detection levels, and accuracy requirements; identifies reporting and data management requirements; and provides a process to ensure coordination between NNSS groundwater sampling programs for sampling of interest to UGTA. This Plan does not address compliance with requirements for wells that supply the NNSS public water system or wells involved in a permitted activity.

  5. UMTRA water sampling and analysis plan, Green River, Utah

    Energy Technology Data Exchange (ETDEWEB)

    Papusch, R.

    1993-12-01

    The purpose of this water sampling and analysis plan (WSAP) is to provide a basis for groundwater and surface water sampling at the Green River Uranium Mill Tailing Remedial Action (UMTRA) Project site. This WSAP identifies and justifies the sampling locations, analytical parameters, detection limits, and sampling frequency for the monitoring locations.

  6. Classifier Directed Data Hybridization for Geographic Sample Supervised Segment Generation

    Directory of Open Access Journals (Sweden)

    Christoff Fourie

    2014-11-01

    Full Text Available Quality segment generation is a well-known challenge and research objective within Geographic Object-based Image Analysis (GEOBIA. Although methodological avenues within GEOBIA are diverse, segmentation commonly plays a central role in most approaches, influencing and being influenced by surrounding processes. A general approach using supervised quality measures, specifically user provided reference segments, suggest casting the parameters of a given segmentation algorithm as a multidimensional search problem. In such a sample supervised segment generation approach, spatial metrics observing the user provided reference segments may drive the search process. The search is commonly performed by metaheuristics. A novel sample supervised segment generation approach is presented in this work, where the spectral content of provided reference segments is queried. A one-class classification process using spectral information from inside the provided reference segments is used to generate a probability image, which in turn is employed to direct a hybridization of the original input imagery. Segmentation is performed on such a hybrid image. These processes are adjustable, interdependent and form a part of the search problem. Results are presented detailing the performances of four method variants compared to the generic sample supervised segment generation approach, under various conditions in terms of resultant segment quality, required computing time and search process characteristics. Multiple metrics, metaheuristics and segmentation algorithms are tested with this approach. Using the spectral data contained within user provided reference segments to tailor the output generally improves the results in the investigated problem contexts, but at the expense of additional required computing time.

  7. Designing a Repetitive Group Sampling Plan for Weibull Distributed Processes

    Directory of Open Access Journals (Sweden)

    Aijun Yan

    2016-01-01

    Full Text Available Acceptance sampling plans are useful tools to determine whether the submitted lots should be accepted or rejected. An efficient and economic sampling plan is very desirable for the high quality levels required by the production processes. The process capability index CL is an important quality parameter to measure the product quality. Utilizing the relationship between the CL index and the nonconforming rate, a repetitive group sampling (RGS plan based on CL index is developed in this paper when the quality characteristic follows the Weibull distribution. The optimal plan parameters of the proposed RGS plan are determined by satisfying the commonly used producer’s risk and consumer’s risk at the same time by minimizing the average sample number (ASN and then tabulated for different combinations of acceptance quality level (AQL and limiting quality level (LQL. The results show that the proposed plan has better performance than the single sampling plan in terms of ASN. Finally, the proposed RGS plan is illustrated with an industrial example.

  8. How Will Teachers Fare in Rhode Island's New Hybrid Pension Plan? Public Pension Project Brief 4

    Science.gov (United States)

    Johnson, Richard W.; Butrica, Barbara A.; Haaga, Owen; Southgate, Benjamin G.

    2014-01-01

    Hybrid retirement plans that combine defined benefit pensions with 401(k) type, defined contribution accounts can play important roles in the reform of public-sector pensions. Summarizing results from our longer report ["How Will Rhode Island's New Hybrid Pension Plan Affect Teachers? A Report of the Public Pension Project" (2014)], this…

  9. 42 CFR 431.978 - Eligibility sampling plan and procedures.

    Science.gov (United States)

    2010-10-01

    ... Section 431.978 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... for Estimating Improper Payments in Medicaid and CHIP § 431.978 Eligibility sampling plan and procedures. (a) Plan approval. For each review year, the agency must— (1) Submit its Medicaid or CHIP...

  10. A novel fluorescent in situ hybridization technique for detection of Rickettsia spp. in archival samples

    DEFF Research Database (Denmark)

    Svendsen, Claus Bo; Boye, Mette; Struve, Carsten

    2009-01-01

    A novel, sensitive and specific method for detecting Rickettsia spp. in archival samples is described. The method involves the use of fluorescently marked oligonucleotide probes for in situ hybridization. Specific hybridization of Ricekttsia was found without problems of cross-reactions with bact......A novel, sensitive and specific method for detecting Rickettsia spp. in archival samples is described. The method involves the use of fluorescently marked oligonucleotide probes for in situ hybridization. Specific hybridization of Ricekttsia was found without problems of cross...

  11. UMTRA water sampling and analysis plan, Lakeview, Oregon

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-29

    The purpose of this document is to provide background, guidance, and justification for water sampling activities for the Lakeview, Oregon, Uranium Mill Tailings Remedial Action (UMTRA) processing and disposal sites. This water sampling and analysis plan will form the basis for groundwater sampling and analysis work orders (WSAWO) to be implemented during 1993. Monitoring at the former Lakeview processing site is for characterization purposes and in preparation for the risk assessment, scheduled for the fall of 1993. Compliance monitoring was conducted at the disposal site. Details of the sampling plan are discussed in Section 5.0.

  12. Sampling and Analysis Plan - Waste Treatment Plant Seismic Boreholes Project

    Energy Technology Data Exchange (ETDEWEB)

    Reidel, Steve P.

    2006-05-26

    This sampling and analysis plan (SAP) describes planned data collection activities for four entry boreholes through the sediment overlying the basalt, up to three new deep rotary boreholes through the basalt and sedimentary interbeds, and one corehole through the basalt and sedimentary interbeds at the Waste Treatment Plant (WTP) site. The SAP will be used in concert with the quality assurance plan for the project to guide the procedure development and data collection activities needed to support borehole drilling, geophysical measurements, and sampling. This SAP identifies the American Society of Testing Materials standards, Hanford Site procedures, and other guidance to be followed for data collection activities.

  13. Validation of a sampling plan to generate food composition data.

    Science.gov (United States)

    Sammán, N C; Gimenez, M A; Bassett, N; Lobo, M O; Marcoleri, M E

    2016-02-15

    A methodology to develop systematic plans for food sampling was proposed. Long life whole and skimmed milk, and sunflower oil were selected to validate the methodology in Argentina. Fatty acid profile in all foods, proximal composition, and calcium's content in milk were determined with AOAC methods. The number of samples (n) was calculated applying Cochran's formula with variation coefficients ⩽12% and an estimate error (r) maximum permissible ⩽5% for calcium content in milks and unsaturated fatty acids in oil. n were 9, 11 and 21 for long life whole and skimmed milk, and sunflower oil respectively. Sample units were randomly collected from production sites and sent to labs. Calculated r with experimental data was ⩽10%, indicating high accuracy in the determination of analyte content of greater variability and reliability of the proposed sampling plan. The methodology is an adequate and useful tool to develop sampling plans for food composition analysis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. A Hybrid Analytical/Simulation Modeling Approach for Planning and Optimizing Mass Tactical Airborne Operations

    Science.gov (United States)

    1995-05-01

    A HYBRID ANALYTICAL/ SIMULATION MODELING APPROACH FOR PLANNING AND OPTIMIZING MASS TACTICAL AIRBORNE OPERATIONS by DAVID DOUGLAS BRIGGS M.S.B.A...COVERED MAY 1995 TECHNICAL REPORT THESIS 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS A HYBRID ANALYTICAL SIMULATION MODELING APPROACH FOR PLANNING AND...are present. Thus, simulation modeling presents itself as an excellent alternate tool for planning because it allows for the modeling of highly complex

  15. Missile trajectory shaping using sampling-based path planning

    OpenAIRE

    Pharpatara, Pawit; Pepy, Romain; Hérissé, Bruno; Bestaoui, Yasmina

    2013-01-01

    International audience; This paper presents missile guidance as a complex robotic problem: a hybrid non-linear system moving in a heterogeneous environment. The proposed solution to this problem combines a sampling-based path planner, Dubins' curves and a locally-optimal guidance law. This algorithm aims to find feasible trajectories that anticipate future flight conditions, especially the loss of manoeuverability at high altitude. Simulated results demonstrate the substantial performance imp...

  16. Livermore Big Trees Park 1998 soil sampling plan

    Energy Technology Data Exchange (ETDEWEB)

    Bainer, R. W.

    1998-10-01

    This sampling plan sets out the sampling goals, rationale, locations, and procedures for a plan to determine the extent of plutonium in soil above background levels in Big Trees Park and identify any possible pathways by which plutonium may have reached the park. The public is invited to witness the sampling at Big Trees Park. The plan has been developed by the U.S. Department of Energy (DOE) and Lawrence Livermore National Laboratory (LLNL) scientists with guidance from the Environmental Protection Agency (EPA), the Radiologic Health and Environmental Health Investigations Branches of the California Health Services Department (CDHS-RHB and CDHS-EHIB), and the Agency for Toxic Substances and Disease Registry (ATSDR). Input from citizens and community organizations was also received during an over-70-day public comment period.

  17. 7 CFR 42.104 - Sampling plans and defects.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Sampling plans and defects. 42.104 Section 42.104 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD...

  18. A Rough Set GA-based Hybrid Method for Robot Path Planning

    Institute of Scientific and Technical Information of China (English)

    Cheng-Dong Wu; Ying Zhang; Meng-Xin Li; Yong Yue

    2006-01-01

    In this paper, a hybrid method based on rough sets and genetic algorithms, is proposed to improve the speed of robot path planning. Decision rules are obtained using rough set theory. A series of available paths are produced by training obtained minimal decision rules. Path populations are optimised by using genetic algorithms until the best path is obtained. Experiment results show that this hybrid method is capable of improving robot path planning speed.

  19. Sampling plans for pest mites on physic nut.

    Science.gov (United States)

    Rosado, Jander F; Sarmento, Renato A; Pedro-Neto, Marçal; Galdino, Tarcísio V S; Marques, Renata V; Erasmo, Eduardo A L; Picanço, Marcelo C

    2014-08-01

    The starting point for generating a pest control decision-making system is a conventional sampling plan. Because the mites Polyphagotarsonemus latus and Tetranychus bastosi are among the most important pests of the physic nut (Jatropha curcas), in the present study, we aimed to establish sampling plans for these mite species on physic nut. Mite densities were monitored in 12 physic nut crops. Based on the obtained results, sampling of P. latus and T. bastosi should be performed by assessing the number of mites per cm(2) in 160 samples using a handheld 20× magnifying glass. The optimal sampling region for T. bastosi is the abaxial surface of the 4th most apical leaf on the branch of the middle third of the canopy. On the abaxial surface, T. bastosi should then be observed on the side parts of the middle portion of the leaf, near its edge. As for P. latus, the optimal sampling region is the abaxial surface of the 4th most apical leaf on the branch of the apical third of the canopy on the abaxial surface. Polyphagotarsonemus latus should then be assessed on the side parts of the leaf's petiole insertion. Each sampling procedure requires 4 h and costs US$ 7.31.

  20. In situ sampling device development engineering task plan

    Energy Technology Data Exchange (ETDEWEB)

    DeFord, D.K.

    1994-10-07

    This engineering task plan (ETP) supports the development for facility use of an improved packaging method or device for the sorbent media used during in situ sampling of waste tanks. Improvement is being sought due to problems with internal and external radioactive contamination. In situ sampling refers to placing sample collection media (primarily sorbent tubes) directly into the tank headspace, then drawing tank gases through the collection media to obtain samples. Development for facility use, includes design, fabrication, and formal documentation of the device. As the most important change to be made is addition of a High Efficiency Particulate Air (HEPA) filter, the device will be referred to in this ETP as the Filter Device or simply the Device. This ETP is intended to be the management plan governing the design, fabrication, and formal documentation of the Filter Device. This plan identifies the engineering services and other resources to accomplish that purpose. The design basis for the development of the Device is presented in this ETP.

  1. Genesis Contingency Planning and Mishap Recovery: The Sample Curation View

    Science.gov (United States)

    Stansbery, E. K.; Allton, J. H.; Allen, C. C.; McNamara, K. M.; Calaway, M.; Rodriques, M. C.

    2007-01-01

    Planning for sample preservation and curation was part of mission design from the beginning. One of the scientific objectives for Genesis included collecting samples of three regimes of the solar wind in addition to collecting bulk solar wind during the mission. Collectors were fabricated in different thicknesses for each regime of the solar wind and attached to separate frames exposed to the solar wind during specific periods of solar activity associated with each regime. The original plan to determine the solar regime sampled for specific collectors was to identify to which frame the collector was attached. However, the collectors were dislodged during the hard landing making identification by frame attachment impossible. Because regimes were also identified by thickness of the collector, the regime sampled is identified by measuring fragment thickness. A variety of collector materials and thin films applied to substrates were selected and qualified for flight. This diversity provided elemental measurement in more than one material, mitigating effects of diffusion rates and/or radiation damage. It also mitigated against different material and substrate strengths resulting in differing effects of the hard landing. For example, silicon crystal substrates broke into smaller fragments than sapphire-based substrates and diamond surfaces were more resilient to flying debris damage than gold. The primary responsibility of the curation team for recovery was process documentation. Contingency planning for the recovery phase expanded this responsibility to include not only equipment to document, but also gather, contain and identify samples from the landing area and the recovered spacecraft. The team developed contingency plans for various scenarios as part of mission planning that included topographic maps to aid in site recovery and identification of different modes of transport and purge capability depending on damage. A clean tent, set-up at Utah Test & Training Range

  2. The Toggle Local Planner for sampling-based motion planning

    KAUST Repository

    Denny, Jory

    2012-05-01

    Sampling-based solutions to the motion planning problem, such as the probabilistic roadmap method (PRM), have become commonplace in robotics applications. These solutions are the norm as the dimensionality of the planning space grows, i.e., d > 5. An important primitive of these methods is the local planner, which is used for validation of simple paths between two configurations. The most common is the straight-line local planner which interpolates along the straight line between the two configurations. In this paper, we introduce a new local planner, Toggle Local Planner (Toggle LP), which extends local planning to a two-dimensional subspace of the overall planning space. If no path exists between the two configurations in the subspace, then Toggle LP is guaranteed to correctly return false. Intuitively, more connections could be found by Toggle LP than by the straight-line planner, resulting in better connected roadmaps. As shown in our results, this is the case, and additionally, the extra cost, in terms of time or storage, for Toggle LP is minimal. Additionally, our experimental analysis of the planner shows the benefit for a wide array of robots, with DOF as high as 70. © 2012 IEEE.

  3. Hybridizing Particle Swarm Optimization and Differential Evolution for the Mobile Robot Global Path Planning

    Directory of Open Access Journals (Sweden)

    Biwei Tang

    2016-05-01

    Full Text Available Global path planning is a challenging issue in the filed of mobile robotics due to its complexity and the nature of nondeterministic polynomial-time hard (NP-hard. Particle swarm optimization (PSO has gained increasing popularity in global path planning due to its simplicity and high convergence speed. However, since the basic PSO has difficulties balancing exploration and exploitation, and suffers from stagnation, its efficiency in solving global path planning may be restricted. Aiming at overcoming these drawbacks and solving the global path planning problem efficiently, this paper proposes a hybrid PSO algorithm that hybridizes PSO and differential evolution (DE algorithms. To dynamically adjust the exploration and exploitation abilities of the hybrid PSO, a novel PSO, the nonlinear time-varying PSO (NTVPSO, is proposed for updating the velocities and positions of particles in the hybrid PSO. In an attempt to avoid stagnation, a modified DE, the ranking-based self adaptive DE (RBSADE, is developed to evolve the personal best experience of particles in the hybrid PSO. The proposed algorithm is compared with four state-of-the-art evolutionary algorithms. Simulation results show that the proposed algorithm is highly competitive in terms of path optimality and can be considered as a vital alternative for solving global path planning.

  4. Final work plan for targeted sampling at Webber, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2006-05-01

    This Work Plan outlines the scope of work for targeted sampling at Webber, Kansas (Figure 1.1). This activity is being conducted at the request of the Kansas Department of Health and Environment (KDHE), in accordance with Section V of the Intergovernmental Agreement between the KDHE and the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA). Data obtained in this sampling event will be used to (1) evaluate the current status of previously detected contamination at Webber and (2) determine whether the site requires further action. This work is being performed on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by the University of Chicago for the U.S. Department of Energy (DOE). The CCC/USDA has entered into an interagency agreement with DOE, under which Argonne provides technical assistance to the CCC/USDA with environmental site characterization and remediation at its former grain storage facilities. Argonne has issued a Master Work Plan (Argonne 2002) that describes the general scope of and guidance for all investigations at former CCC/USDA facilities in Kansas. The Master Work Plan, approved by the KDHE, contains the materials common to investigations at all locations in Kansas. This document should be consulted for complete details of the technical activities proposed at the former CCC/USDA facility in Webber.

  5. Soil Sampling Plan for the transuranic storage area soil overburden and final report: Soil overburden sampling at the RWMC transuranic storage area

    Energy Technology Data Exchange (ETDEWEB)

    Stanisich, S.N.

    1994-12-01

    This Soil Sampling Plan (SSP) has been developed to provide detailed procedural guidance for field sampling and chemical and radionuclide analysis of selected areas of soil covering waste stored at the Transuranic Storage Area (TSA) at the Idaho National Engineering Laboratory`s (INEL) Radioactive Waste Management Complex (RWMC). The format and content of this SSP represents a complimentary hybrid of INEL Waste Management--Environmental Restoration Program, and Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) Remedial Investigation/Feasibility Study (RI/FS) sampling guidance documentation. This sampling plan also functions as a Quality Assurance Project Plan (QAPP). The QAPP as a controlling mechanism during sampling to ensure that all data collected are valid, reliabile, and defensible. This document outlines organization, objectives and quality assurance/quality control (QA/QC) activities to achieve the desired data quality goals. The QA/QC requirements for this project are outlined in the Data Collection Quality Assurance Plan (DCQAP) for the Buried Waste Program. The DCQAP is a program plan and does not outline the site specific requirements for the scope of work covered by this SSP.

  6. Nuclear-Renewable Hybrid Energy System Market Analysis Plans

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, Mark

    2016-06-09

    This presentation describes nuclear-renewable hybrid energy systems (N-R HESs), states their potential benefits, provides figures for the four tightly coupled N-R HESs that NREL is currently analyzing, and outlines the analysis process that is underway.

  7. A hybrid travel time prediction framework for planned motorway roadworks

    NARCIS (Netherlands)

    Calvert, S.C.; Lint, J.W.C. van; Hoogendoorn, S.P.

    2010-01-01

    In this paper we propose a hybrid motorway travel time prediction framework aimed at providing pre-trip travel information in case of roadworks. The framework utilises a first order macroscopic traffic flow model to predict the consequences in travel time of changes in both traffic demand and roadwa

  8. Validation of Statistical Sampling Algorithms in Visual Sample Plan (VSP): Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Nuffer, Lisa L; Sego, Landon H.; Wilson, John E.; Hassig, Nancy L.; Pulsipher, Brent A.; Matzke, Brett D.

    2009-02-18

    The U.S. Department of Homeland Security, Office of Technology Development (OTD) contracted with a set of U.S. Department of Energy national laboratories, including the Pacific Northwest National Laboratory (PNNL), to write a Remediation Guidance for Major Airports After a Chemical Attack. The report identifies key activities and issues that should be considered by a typical major airport following an incident involving release of a toxic chemical agent. Four experimental tasks were identified that would require further research in order to supplement the Remediation Guidance. One of the tasks, Task 4, OTD Chemical Remediation Statistical Sampling Design Validation, dealt with statistical sampling algorithm validation. This report documents the results of the sampling design validation conducted for Task 4. In 2005, the Government Accountability Office (GAO) performed a review of the past U.S. responses to Anthrax terrorist cases. Part of the motivation for this PNNL report was a major GAO finding that there was a lack of validated sampling strategies in the U.S. response to Anthrax cases. The report (GAO 2005) recommended that probability-based methods be used for sampling design in order to address confidence in the results, particularly when all sample results showed no remaining contamination. The GAO also expressed a desire that the methods be validated, which is the main purpose of this PNNL report. The objective of this study was to validate probability-based statistical sampling designs and the algorithms pertinent to within-building sampling that allow the user to prescribe or evaluate confidence levels of conclusions based on data collected as guided by the statistical sampling designs. Specifically, the designs found in the Visual Sample Plan (VSP) software were evaluated. VSP was used to calculate the number of samples and the sample location for a variety of sampling plans applied to an actual release site. Most of the sampling designs validated are

  9. Selection of a Planning Horizon for a Hybrid Microgrid Using Simulated Wind Forecasts

    Science.gov (United States)

    2014-12-01

    Craparo Dashi I. Singham Naval Postgraduate School 1411 Cunningham Road Monterey, CA, 93943 USA ABSTRACT Hybrid microgrids containing renewable energy ...produced is at least as great as the total load. Energy is produced by generators, wind turbines, purchases from the commercial grid, and discharge of the...A PLANNING HORIZON FOR A HYBRID MICROGRID USING SIMULATED WIND FORECASTS Mumtaz Karatas Turkish Naval Academy Tuzla, Istanbul, 34942, TURKEY Emily M

  10. 241-Z-361 Sludge Characterization Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    BANNING, D.L.

    1999-08-05

    This sampling and analysis plan (SAP) identifies the type, quantity, and quality of data needed to support characterization of the sludge that remains in Tank 241-2-361. The procedures described in this SAP are based on the results of the 241-2-361 Sludge Characterization Data Quality Objectives (DQO) (BWHC 1999) process for the tank. The primary objectives of this project are to evaluate the contents of Tank 241-2-361 in order to resolve safety and safeguards issues and to assess alternatives for sludge removal and disposal.

  11. 241-Z-361 Sludge Characterization Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    BANNING, D.L.

    1999-07-29

    This sampling and analysis plan (SAP) identifies the type, quantity, and quality of data needed to support characterization of the sludge that remains in Tank 241-2-361. The procedures described in this SAP are based on the results of the 241-2-361 Sludge Characterization Data Quality Objectives (DQO) (BWHC 1999) process for the tank. The primary objectives of this project are to evaluate the contents of Tank 241-2-361 in order to resolve safety and safeguards issues and to assess alternatives for sludge removal and disposal.

  12. 34 CFR Appendix A to Subpart N of... - Sample Default Prevention Plan

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Sample Default Prevention Plan A Appendix A to Subpart... Default Rates Pt. 668, Subpt. N, App. A Appendix A to Subpart N of Part 668—Sample Default Prevention Plan This appendix is provided as a sample plan for those institutions developing a default prevention plan...

  13. Sampling-based Algorithms for Optimal Motion Planning

    CERN Document Server

    Karaman, Sertac

    2011-01-01

    During the last decade, sampling-based path planning algorithms, such as Probabilistic RoadMaps (PRM) and Rapidly-exploring Random Trees (RRT), have been shown to work well in practice and possess theoretical guarantees such as probabilistic completeness. However, little effort has been devoted to the formal analysis of the quality of the solution returned by such algorithms, e.g., as a function of the number of samples. The purpose of this paper is to fill this gap, by rigorously analyzing the asymptotic behavior of the cost of the solution returned by stochastic sampling-based algorithms as the number of samples increases. A number of negative results are provided, characterizing existing algorithms, e.g., showing that, under mild technical conditions, the cost of the solution returned by broadly used sampling-based algorithms converges almost surely to a non-optimal value. The main contribution of the paper is the introduction of new algorithms, namely, PRM* and RRT*, which are provably asymptotically opti...

  14. Sampling and Analysis Plan for K Basins Debris

    Energy Technology Data Exchange (ETDEWEB)

    WESTCOTT, J.L.

    2000-06-21

    This Sampling and Analysis Plan presents the rationale and strategy for sampling and analysis activities to support removal of debris from the K-East and K-West Basins located in the 100K Area at the Hanford Site. This project is focused on characterization to support waste designation for disposal of waste at the Environmental Restoration Disposal Facility (ERDF). This material has previously been dispositioned at the Hanford Low-Level Burial Grounds or Central Waste Complex. The structures that house the basins are classified as radioactive material areas. Therefore, all materials removed from the buildings are presumed to be radioactively contaminated. Because most of the materials that will be addressed under this plan will be removed from the basins, and because of the cost associated with screening materials for release, it is anticipated that all debris will be managed as low-level waste. Materials will be surveyed, however, to estimate radionuclide content for disposal and to determine that the debris is not contaminated with levels of transuranic radionuclides that would designate the debris as transuranic waste.

  15. Abbreviated sampling and analysis plan for planning decontamination and decommissioning at Test Reactor Area (TRA) facilities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    The objective is to sample and analyze for the presence of gamma emitting isotopes and hazardous constituents within certain areas of the Test Reactor Area (TRA), prior to D and D activities. The TRA is composed of three major reactor facilities and three smaller reactors built in support of programs studying the performance of reactor materials and components under high neutron flux conditions. The Materials Testing Reactor (MTR) and Engineering Test Reactor (ETR) facilities are currently pending D/D. Work consists of pre-D and D sampling of designated TRA (primarily ETR) process areas. This report addresses only a limited subset of the samples which will eventually be required to characterize MTR and ETR and plan their D and D. Sampling which is addressed in this document is intended to support planned D and D work which is funded at the present time. Biased samples, based on process knowledge and plant configuration, are to be performed. The multiple process areas which may be potentially sampled will be initially characterized by obtaining data for upstream source areas which, based on facility configuration, would affect downstream and as yet unsampled, process areas. Sampling and analysis will be conducted to determine the level of gamma emitting isotopes and hazardous constituents present in designated areas within buildings TRA-612, 642, 643, 644, 645, 647, 648, 663; and in the soils surrounding Facility TRA-611. These data will be used to plan the D and D and help determine disposition of material by D and D personnel. Both MTR and ETR facilities will eventually be decommissioned by total dismantlement so that the area can be restored to its original condition.

  16. UMTRA Project water sampling and analysis plan, Salt Lake City, Utah. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    This water sampling and analysis plan describes planned, routine ground water sampling activities at the US Department of Energy Uranium Mill Tailings Remedial Action Project site in Salt Lake City, Utah. This plan identifies and justifies sampling locations, analytical parameters, detection limits, and sampling frequencies for routine monitoring of ground water, sediments, and surface waters at monitoring stations on the site.

  17. Hybrid nested sampling algorithm for Bayesian model selection applied to inverse subsurface flow problems

    Energy Technology Data Exchange (ETDEWEB)

    Elsheikh, Ahmed H., E-mail: aelsheikh@ices.utexas.edu [Institute for Computational Engineering and Sciences (ICES), University of Texas at Austin, TX (United States); Institute of Petroleum Engineering, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Wheeler, Mary F. [Institute for Computational Engineering and Sciences (ICES), University of Texas at Austin, TX (United States); Hoteit, Ibrahim [Department of Earth Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal (Saudi Arabia)

    2014-02-01

    A Hybrid Nested Sampling (HNS) algorithm is proposed for efficient Bayesian model calibration and prior model selection. The proposed algorithm combines, Nested Sampling (NS) algorithm, Hybrid Monte Carlo (HMC) sampling and gradient estimation using Stochastic Ensemble Method (SEM). NS is an efficient sampling algorithm that can be used for Bayesian calibration and estimating the Bayesian evidence for prior model selection. Nested sampling has the advantage of computational feasibility. Within the nested sampling algorithm, a constrained sampling step is performed. For this step, we utilize HMC to reduce the correlation between successive sampled states. HMC relies on the gradient of the logarithm of the posterior distribution, which we estimate using a stochastic ensemble method based on an ensemble of directional derivatives. SEM only requires forward model runs and the simulator is then used as a black box and no adjoint code is needed. The developed HNS algorithm is successfully applied for Bayesian calibration and prior model selection of several nonlinear subsurface flow problems.

  18. Fluoroscence in situ hybridization of chicken intestinal samples with bacterial rRNA targeted oligonucleotide probes

    DEFF Research Database (Denmark)

    Olsen, Katja Nyholm; Francesch, M.; Christensen, Henrik

    2006-01-01

    The objective was to develop a fast and accurate molecular method for the quantification of the intestinal flora in chickens by rRNA fluorescence in situ hybridization (FISH). Seven weeks old conventionally reared Lohmann hens were used to set up the method. To sample ileal intestinal content......, the distal part from Meckels diverticulum to the ileo-caecal junction was removed. Fixation was performed in ethanol and phosphate buffered saline. After washing by centrifugation, the sample was resuspended in pre-heated hybridization buffer with oligonucleotide probe labelled with Cy3 (10ng/µl). The cells...... were hybridized for 24-72h, centrifuged, washed with pre-heated hybridization buffer, centrifuged and resuspended in Millipore quality water before filtration onto a 0.22 µm black polycarbonate filter. The probes used in this study were, LGC354A, LGC354B, LGC354C, Strc493, Bacto1080, Sal3, Chis150, EUB...

  19. A Hybrid Metaheuristic DE/CS Algorithm for UCAV Three-Dimension Path Planning

    OpenAIRE

    Gaige Wang; Lihong Guo; Hong Duan; Heqi Wang; Luo Liu; Mingzhen Shao

    2012-01-01

    Three-dimension path planning for uninhabited combat air vehicle (UCAV) is a complicated high-dimension optimization problem, which primarily centralizes on optimizing the flight route considering the different kinds of constrains under complicated battle field environments. A new hybrid metaheuristic differential evolution (DE) and cuckoo search (CS) algorithm is proposed to solve the UCAV three-dimension path planning problem. DE is applied to optimize the process of selecting cuckoos of th...

  20. Planning "and" Sprinting: Use of a Hybrid Project Management Methodology within a CIS Capstone Course

    Science.gov (United States)

    Baird, Aaron; Riggins, Frederick J.

    2012-01-01

    An increasing number of information systems projects in industry are managed using hybrid project management methodologies, but this shift in project management methods is not fully represented in our CIS curriculums. CIS capstone courses often include an applied project that is managed with traditional project management methods (plan first,…

  1. Planning "and" Sprinting: Use of a Hybrid Project Management Methodology within a CIS Capstone Course

    Science.gov (United States)

    Baird, Aaron; Riggins, Frederick J.

    2012-01-01

    An increasing number of information systems projects in industry are managed using hybrid project management methodologies, but this shift in project management methods is not fully represented in our CIS curriculums. CIS capstone courses often include an applied project that is managed with traditional project management methods (plan first,…

  2. Probabilistic Planning with Imperfect Sensing Actions Using Hybrid Probabilistic Logic Programs

    Science.gov (United States)

    Saad, Emad

    Effective planning in uncertain environment is important to agents and multi-agents systems. In this paper, we introduce a new logic based approach to probabilistic contingent planning (probabilistic planning with imperfect sensing actions), by relating probabilistic contingent planning to normal hybrid probabilistic logic programs with probabilistic answer set semantics [24]. We show that any probabilistic contingent planning problem can be encoded as a normal hybrid probabilistic logic program. We formally prove the correctness of our approach. Moreover, we show that the complexity of finding a probabilistic contingent plan in our approach is NP-complete. In addition, we show that any probabilistic contingent planning problem, \\cal PP, can be encoded as a classical normal logic program with answer set semantics, whose answer sets corresponds to valid trajectories in \\cal PP. We show that probabilistic contingent planning problems can be encoded as SAT problems. We present a new high level probabilistic action description language that allows the representation of sensing actions with probabilistic outcomes.

  3. A sample lesson plan for the course English Composition II

    Directory of Open Access Journals (Sweden)

    Córdoba Cubillo, Patricia

    2005-03-01

    Full Text Available The goal of this article is to present a lesson plan and a series of sample tasks to help the instructors from the course English Composition II, at the School of Modern Languages from the University of Costa Rica, to guide students write an essay integrating the four skills: listening, speaking, reading, and writing. These activities will be a source of comprehensible input for the learners that will hopefully result in a good writing piece. El objetivo de este artículo es presentar un plan de lección y una serie de actividades que le ayudarán a los y las instructoras del curso Composición Inglesa II de la Escuela de Lenguas Modernas de la Universidad de Costa Rica a guiar a sus estudiantes a escribir un ensayo integrando las cuatro macro-destrezas, a saber comprensión auditiva, conversación, lectura y escritura. Mediante estas actividades se espera que los estudiantes elaboren un ensayo de calidad.

  4. SVC Planning in Large–scale Power Systems via a Hybrid Optimization Method

    DEFF Research Database (Denmark)

    Yang, Guang ya; Majumder, Rajat; Xu, Zhao

    2009-01-01

    The research on allocation of FACTS devices has attracted quite a lot interests from various aspects. In this paper, a hybrid model is proposed to optimise the number, location as well as the parameter settings of static Var compensator (SVC) deployed in large–scale power systems. The model utili...... a candidate solution pool. Then in the second stage, the candidates are presented to a linear planning model to investigate the system optimal loadability, hence the optimal solution for SVC planning can be achieved. The method is presented to IEEE 300–bus system....... utilises the result of vulnerability assessment for determining the candidate locations. A hybrid optimisation method including two stages is proposed to find out the optimal solution of SVC in large– scale planning problem. In the first stage, a conventional genetic algorithm (GA) is exploited to generate...

  5. A ZERO SAMPLING PLAN FOR THE MODERATION OF EXAMINATION PAPERS

    Directory of Open Access Journals (Sweden)

    W. Van Wijck

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Quality assurance within local educational institutions has been under the spotlight in recent years. In particular these institutions are increasingly subjected to minimum standards specified by controlling bodies such as the Higher Education Quality Committee and others. The moderation of examination papers is an important quality assurance activity to ensure that an examination paper’s standard, content, span and marking are fair and reasonable. This paper describes a sampling plan to determine the number of answer books to be checked to confirm that individual marks were awarded correctly. The sampling procedure relates the confidence that marks awarded in a set of examination books meets a specified minimum standard to the number of books moderated.

    AFRIKAANSE OPSOMMING: Gehalteversekering binne plaaslike opvoedkundige instellings word toenemend onderwerp aan minimum standaarde soos neergelê deur die Kwaliteitskomitee vir Hoër Onderwys en ander. Die moderering van eksamenantwoordstelle is 'n belangrike gehalteversekeringsaktiwiteit wat verseker dat 'n eksamen se standaard, inhoud, bestek en nasien regverdig en redelik is. Die artikel beskryf ‘n steekproefplan vir die proses om individueel toegekende punte vir korrektheid na te gaan. Die voorgestelde prosedure gee die verband tussen die sekerheid dat die punte toegeken deur die eksaminator voldoen aan ‘n gespesifieerde minimum standaard en die aantal boeke wat gemodereer moet word (steekproefgrootte.

  6. Tank 241-Z-361 vapor sampling and analysis plan

    Energy Technology Data Exchange (ETDEWEB)

    BANNING, D.L.

    1999-02-23

    Tank 241-Z-361 is identified in the Hanford Federal Facility Agreement and Consent Order (commonly referred to as the Tri-Party Agreement), Appendix C, (Ecology et al. 1994) as a unit to be remediated under the authority of the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). As such, the U.S. Environmental Protection Agency will serve as the lead regulatory agency for remediation of this tank under the CERCLA process. At the time this unit was identified as a CERCLA site under the Tri-Party Agreement, it was placed within the 200-ZP-2 Operable Unit. In 1997, The Tri-parties redefined 200 Area Operable Units into waste groupings (Waste Site Grouping for 200 Areas Soils Investigations [DOE-RL 1992 and 1997]). A waste group contains waste sites that share similarities in geological conditions, function, and types of waste received. Tank 241-Z-361 is identified within the CERCLA Plutonium/Organic-rich Process Condensate/Process Waste Group (DOE-RL 1992). The Plutonium/Organic-rich Process Condensate/Process Waste Group has been prioritized for remediation beginning in the year 2004. Results of Tank 216-Z-361 sampling and analysis described in this Sampling and Analysis Plan (SAP) and in the SAP for sludge sampling (to be developed) will determine whether expedited response actions are required before 2004 because of the hazards associated with tank contents. Should data conclude that remediation of this tank should occur earlier than is planned for the other sites in the waste group, it is likely that removal alternatives will be analyzed in a separate Engineering Evaluation/Cost Analysis (EE/CA). Removal actions would proceed after the U.S. Environmental Protection Agency (EPA) signs an Action Memorandum describing the selected removal alternative for Tank 216-Z-361. If the data conclude that there is no immediate threat to human health and the environment from this tank, remedial actions for the tank will be defined in a

  7. Designing a multiple dependent state sampling plan based on the coefficient of variation.

    Science.gov (United States)

    Yan, Aijun; Liu, Sanyang; Dong, Xiaojuan

    2016-01-01

    A multiple dependent state (MDS) sampling plan is developed based on the coefficient of variation of the quality characteristic which follows a normal distribution with unknown mean and variance. The optimal plan parameters of the proposed plan are solved by a nonlinear optimization model, which satisfies the given producer's risk and consumer's risk at the same time and minimizes the sample size required for inspection. The advantages of the proposed MDS sampling plan over the existing single sampling plan are discussed. Finally an example is given to illustrate the proposed plan.

  8. Hybrid MCDA Methods to Integrate Multiple Ecosystem Services in Forest Management Planning: A Critical Review

    Science.gov (United States)

    Uhde, Britta; Andreas Hahn, W.; Griess, Verena C.; Knoke, Thomas

    2015-08-01

    Multi-criteria decision analysis (MCDA) is a decision aid frequently used in the field of forest management planning. It includes the evaluation of multiple criteria such as the production of timber and non-timber forest products and tangible as well as intangible values of ecosystem services (ES). Hence, it is beneficial compared to those methods that take a purely financial perspective. Accordingly, MCDA methods are increasingly popular in the wide field of sustainability assessment. Hybrid approaches allow aggregating MCDA and, potentially, other decision-making techniques to make use of their individual benefits and leading to a more holistic view of the actual consequences that come with certain decisions. This review is providing a comprehensive overview of hybrid approaches that are used in forest management planning. Today, the scientific world is facing increasing challenges regarding the evaluation of ES and the trade-offs between them, for example between provisioning and regulating services. As the preferences of multiple stakeholders are essential to improve the decision process in multi-purpose forestry, participatory and hybrid approaches turn out to be of particular importance. Accordingly, hybrid methods show great potential for becoming most relevant in future decision making. Based on the review presented here, the development of models for the use in planning processes should focus on participatory modeling and the consideration of uncertainty regarding available information.

  9. Multi-Objective Hybrid Optimal Control for Interplanetary Mission Planning

    Science.gov (United States)

    Englander, Jacob

    2015-01-01

    Preliminary design of low-thrust interplanetary missions is a highly complex process. The mission designer must choose discrete parameters such as the number of flybys, the bodies at which those flybys are performed, and in some cases the final destination. Because low-thrust trajectory design is tightly coupled with systems design, power and propulsion characteristics must be chosen as well. In addition, a time-history of control variables must be chosen which defines the trajectory. There are often many thousands, if not millions, of possible trajectories to be evaluated. The customer who commissions a trajectory design is not usually interested in a point solution, but rather the exploration of the trade space of trajectories between several different objective functions. This can be very expensive process in terms of the number of human analyst hours required. An automated approach is therefore very desirable. This work presents such an approach by posing the mission design problem as a multi-objective hybrid optimal control problem. The methods is demonstrated on hypothetical mission to the main asteroid belt and to Deimos.

  10. Uniform sampling analysis of a hybrid phase-locked loop with a sample-and-hold phase detector

    Science.gov (United States)

    Barab, S.; Mcbride, A. L.

    1975-01-01

    Phase-locked-loop (PLL) bit synchronizers often employ integrate-and-dump type phase detectors that provide phase error information only at discrete points in time. Usually these phase detectors are followed by sample-and-hold circuits to produce a stairstep error voltage as the input to a standard analog circuit loop filter. When the loop is configured in this manner, it is referred to as a hybrid PLL. Sampled-data analysis methods (Z transforms) are used to determine the stability and transient response of this loop.

  11. Group Acceptance Sampling Plan for Lifetime Data Using Generalized Pareto Distribution

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam

    2010-02-01

    Full Text Available In this paper, a group acceptance sampling plan (GASP is introduced for the situations when lifetime of the items follows the generalized Pareto distribution. The design parameters such as minimum group size and acceptance number are determined when the consumer’s risk and the test termination time are specified. The proposed sampling plan is compared with the existing sampling plan. It is concluded that the proposed sampling plan performs better than the existing plan in terms of minimum sample size required to reach the same decision.

  12. A hybrid TOPSIS-BSC method for strategic planning

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Shojaee

    2012-09-01

    Full Text Available For years, tangible assets used to be the most important precious wealth of organizations. However, the recent advances in technology has changed this concept and today, intangible assets such as human resources, customers, processes are playing essential roles on making strategies. In this paper, we present a study to setup appropriate strategies using the implementation of balanced score card in four perspectives of customers, processes, learning and financial. The proposed study of this paper gathers important factors through three different brainstorming sessions and prioritize them using TOPSIS method. Based on the results of MCDM technique, selecting appropriate target market for penetration is the number one priority followed by having good accounting system and preparing for more diversified production. These are the most important items influencing strategic planning. Therefore, the study uses BSC for the first two important strategies and discusses possible actions for productivity improvement.

  13. Comparison of clinical samples for visceral Leishmaniasis diagnosis in asymptomatic dogs by PCR hybridization

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Sidney A.; Ituassu, Leonardo T.; Melo, Maria N. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Parasitologia], e-mail: saninoalmeida@gmail.com, e-mail: Itituassu@yahoo.com.br, e-mail: melo@icb.ufmg.br; Leite, Rodrigo S.; Andrade, Antero S.R. [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN/MG), Belo Horizonte, MG (Brazil)], e-mail: rleite2005@gmail.com, e-mail: antero@cdtn.br

    2009-07-01

    The canine visceral leishmaniasis (CVL) diagnosis still represents a challenge because of complexity of this disease. The aim of present study was to compare different clinical samples for diagnosis of CVL by Polymerase Chain Reaction (PCR) combined with hybridization of {sup 32}P labeled probes. Bone marrow (BM), skin biopsy (SB), peripheral blood (PB) and conjunctival swab (CS) were used in this work. With this purpose 40 asymptomatic dogs, all positive by parasitological test, were obtained. From each animal were collected SB with sterile punches from ear internal surface, 1.0 mL of PB, BM aspirates from sternum and CS from both lower eyelid. Each clinical sample was submitted to suitable DNA purification process and PCR-hybridization assays. The positive results obtained with PCR were 55%, 25%, 30% and 22.5% for CS, BM, SB and PB respectively while the PCR followed by hybridization showed a positivity of 87.5%, 50%, 45% and 27.5% respectively. The hybridization assay was able to increase the PCR positivity in all kinds of clinical samples. The best performance was obtained using CS samples. We concluded that the PCR associated with DNA radioactive probes was a very sensitive tool for diagnosis of CVL in asymptomatic dogs and the CS has an important potential for regular screening of dogs. (author)

  14. Hybrid algorithm of ensemble transform and importance sampling for assimilation of non-Gaussian observations

    Directory of Open Access Journals (Sweden)

    Shin'ya Nakano

    2014-05-01

    Full Text Available A hybrid algorithm that combines the ensemble transform Kalman filter (ETKF and the importance sampling approach is proposed. Since the ETKF assumes a linear Gaussian observation model, the estimate obtained by the ETKF can be biased in cases with nonlinear or non-Gaussian observations. The particle filter (PF is based on the importance sampling technique, and is applicable to problems with nonlinear or non-Gaussian observations. However, the PF usually requires an unrealistically large sample size in order to achieve a good estimation, and thus it is computationally prohibitive. In the proposed hybrid algorithm, we obtain a proposal distribution similar to the posterior distribution by using the ETKF. A large number of samples are then drawn from the proposal distribution, and these samples are weighted to approximate the posterior distribution according to the importance sampling principle. Since the importance sampling provides an estimate of the probability density function (PDF without assuming linearity or Gaussianity, we can resolve the bias due to the nonlinear or non-Gaussian observations. Finally, in the next forecast step, we reduce the sample size to achieve computational efficiency based on the Gaussian assumption, while we use a relatively large number of samples in the importance sampling in order to consider the non-Gaussian features of the posterior PDF. The use of the ETKF is also beneficial in terms of the computational simplicity of generating a number of random samples from the proposal distribution and in weighting each of the samples. The proposed algorithm is not necessarily effective in case that the ensemble is located distant from the true state. However, monitoring the effective sample size and tuning the factor for covariance inflation could resolve this problem. In this paper, the proposed hybrid algorithm is introduced and its performance is evaluated through experiments with non-Gaussian observations.

  15. Multi-site production planning in hybrid make-to-stock/make-to-order production environment

    Science.gov (United States)

    Rafiei, Hamed; Rabbani, Masoud; Kokabi, Reza

    2014-06-01

    Today competitive environment has enforced practitioners and researchers to pay great attention to issues enhancing both production and marketing competitiveness. To do so, it has been obligatory for the firms to consider production side activities while customer requirements are on the other side of competition. In this regard, hybrid make-to-stock (MTS)/make-to-order (MTO) production systems have revealed outstanding results. This paper addresses multi-site production planning of a hybrid manufacturing firm for the first time in the hybrid systems' body of literature. In this regard, a network of suppliers, manufacturers and customers is considered for which a mixed-integer mathematical model is proposed. Objective function of the proposed mathematical model seeks to maximize profitability of the manufacturing firm. Because of computational complexity of the developed mathematical model, a genetic algorithm is developed upon which numerical experiments are reported in order to show validity and applicability of the proposed model.

  16. Path Planning and Trajectory Control of Collaborative Mobile Robots Using Hybrid Control Architecture

    Directory of Open Access Journals (Sweden)

    Trevor Davies

    2008-08-01

    Full Text Available This paper presents the development and implementation a hybrid control architecture to direct a collective of three X80 mobile robots to multiple user-defined waypoints. The Genetic Algorithm Path Planner created an optimized, reduction in the time to complete the task, path plan for each robot in the collective such that each waypoint was visited once without colliding with a priori obstacles. The deliberative Genetic Algorithm Path Planner was then coupled with a reactive Potential Field Trajectory Planner and kinematic based controller to create a hybrid control architecture allowing the mobile robot to navigate between multiple user-defined waypoints, while avoiding a priori obstacles and obstacles detected using the robots' range sensors. The success of this hybrid control architecture was proven through simulation and experimentation using three of Dr. Robot's ™ wireless X80 mobile robots.

  17. Support for the 7-factor hybrid model of PTSD in a community sample.

    Science.gov (United States)

    Seligowski, Antonia V; Orcutt, Holly K

    2016-03-01

    Research suggests that 4-factor models of posttraumatic stress disorder (PTSD) may be improved upon by the addition of novel factors, such as Dysphoric Arousal, Externalizing Behaviors, and Anhedonia. However, a novel 7-factor hybrid model has demonstrated superior fit in veteran and undergraduate samples. The current study sought to replicate this finding in a trauma-exposed community sample and examined relations with positive (PA) and negative affect (NA). Participants included 403 adults (M(age) = 37.75) recruited through Amazon's MTurk. PTSD was measured using the PTSD Checklist-5 (PCL-5). Confirmatory factor analyses were conducted in Mplus. The 7-factor hybrid model demonstrated good fit: CFI = .96, TLI = .95, RMSEA = .06 (90% CI [.05, .07]), SRMR = .03. This model was superior to the 5- and 6-factor models. All factors demonstrated significant relations with PA and NA, the largest of which were the Externalizing Behaviors (with NA) and Anhedonia (with PA) factors. Results provide support for the 7-factor hybrid model of PTSD using the PCL-5 in a community sample. Findings replicate previous research suggesting that PTSD is highly related to NA, which has been purported as an underlying dimension of PTSD. It is recommended that future research use clinical measures to further examine the hybrid model. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  18. Optimal Planning and Operation of Hybrid Energy System Supplemented by Storage Devices

    DEFF Research Database (Denmark)

    Javadi, Mohammad Sadegh; Anvari-Moghaddam, Amjad; Guerrero, Josep M.

    2017-01-01

    This paper presents a two-stage model for optimal planning and operation of a distribution network. Optimal siting and sizing of renewable energy sources (RES) as well as electrical energy storage (EES) systems are considered in the proposed hybrid energy system. In this context, the planning...... problem is considered as a master problem, while there are different sub-problems associated with the short-term operational problem. To properly handle the uncertainties of forecasted load as well as renewable power generations, fair stochastic models are involved in the sub-problems based on historical...

  19. Motion Planning for Vibration Reducing of Free-floating Redundant Manipulators Based on Hybrid Optimization Approach

    Institute of Scientific and Technical Information of China (English)

    LIAO Yihuan; LI Daokui; TANG Guojin

    2011-01-01

    This paper is concerned with optimal motion planning for vibration reducing of flee-floating flexible redundant manipulators.Firstly,dynamic model of the system is established based on Lagrange method,and the motion planning model for vibration reducing is proposed.Secondly,a hybrid optimization approach employing Gauss pseudospectral method(GPM) and direct shooting method(DSM),is proposed to solve the motion planning problem.In this approach,the motion planning problem is transformed into a non-linear parameter optimization problem using GPM,and genetic algorithm(GA) is employed to locate the approximate solution.Subsequently,an optimization model is formulated based on DSM,and sequential quadratic programming (SQP) algorithm is used to obtain the accurate solution,with the approximate solution as an initial reference solution.Finally,several numerical simulations are investigated,and the global vibration or residual vibration of flexible link is obviously reduced by the joint trajectory which is obtained by the hybrid optimization approach.The numerical simulation results indicate that the approach is effective and stable to the motion planning problem of vibration reducing.

  20. Process planning optimization on turning machine tool using a hybrid genetic algorithm with local search approach

    Directory of Open Access Journals (Sweden)

    Yuliang Su

    2015-04-01

    Full Text Available A turning machine tool is a kind of new type of machine tool that is equipped with more than one spindle and turret. The distinctive simultaneous and parallel processing abilities of turning machine tool increase the complexity of process planning. The operations would not only be sequenced and satisfy precedence constraints, but also should be scheduled with multiple objectives such as minimizing machining cost, maximizing utilization of turning machine tool, and so on. To solve this problem, a hybrid genetic algorithm was proposed to generate optimal process plans based on a mixed 0-1 integer programming model. An operation precedence graph is used to represent precedence constraints and help generate a feasible initial population of hybrid genetic algorithm. Encoding strategy based on data structure was developed to represent process plans digitally in order to form the solution space. In addition, a local search approach for optimizing the assignments of available turrets would be added to incorporate scheduling with process planning. A real-world case is used to prove that the proposed approach could avoid infeasible solutions and effectively generate a global optimal process plan.

  1. Sampling-based Motion Planning: Analysis and Path Quality

    NARCIS (Netherlands)

    Geraerts, R.J.

    2006-01-01

    One of the fundamental tasks robots have to perform is planning their motions while avoiding collisions with obstacles in the environment. This is the central topic of the thesis. We restrict ourselves to motion planning for two- and three-dimensional rigid bodies and articulated robots moving in st

  2. Hybrid supply chain model for material requirement planning under financial constraints: A case study

    Science.gov (United States)

    Curci, Vita; Dassisti, Michele; Josefa, Mula Bru; Manuel, Díaz Madroñero

    2014-10-01

    Supply chain model (SCM) are potentially capable to integrate different aspects in supporting decision making for enterprise management tasks. The aim of the paper is to propose an hybrid mathematical programming model for optimization of production requirements resources planning. The preliminary model was conceived bottom-up from a real industrial case analysed oriented to maximize cash flow. Despite the intense computational effort required to converge to a solution, optimisation done brought good result in solving the objective function.

  3. A spatial orthogonal allocation and heterogeneous cultural hybrid algorithm for multirobot exploration mission planning

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A spatial orthogonal allocation method is devised for multirobot tasks allocation.A 3D space model is adopted to describe exploration mission;meanwhile spatial orthogonal tentative technology is utilized to update the attractor position for load balance.Heterogeneous interactive cultural hybrid architecture is proposed to solve a robot route planning problem;it utilizes good-point-set to initialize population spaces,redefine novel evolution model and particle evolution ability,and introduce near-neighbor lo...

  4. Coupled thermal model of photovoltaic-thermoelectric hybrid panel for sample cities in Europe

    DEFF Research Database (Denmark)

    Rezaniakolaei, Alireza; Sera, Dezso; Rosendahl, Lasse Aistrup

    2016-01-01

    generation by the TEG is insignificant compared to electrical output by the PV panel, and the TEG plays only a small role on power generation in the hybrid PV/TEG panel. However, contribution of the TEG in the power generation can be improved via higher ZT thermoelectric materials and geometry optimization......In general, modeling of photovoltaic-thermoelectric (PV/TEG) hybrid panels have been mostly simplified and disconnected from the actual ambient conditions and thermal losses from the panel. In this study, a thermally coupled model of PV/TEG panel is established to precisely predict performance...... of the hybrid system under different weather conditions. The model takes into account solar irradiation, wind speed and ambient temperature as well as convective and radiated heat losses from the front and rear surfaces of the panel. The model is developed for three sample cities in Europe with different...

  5. A hybrid simulation approach for integrating safety behavior into construction planning: An earthmoving case study.

    Science.gov (United States)

    Goh, Yang Miang; Askar Ali, Mohamed Jawad

    2016-08-01

    One of the key challenges in improving construction safety and health is the management of safety behavior. From a system point of view, workers work unsafely due to system level issues such as poor safety culture, excessive production pressure, inadequate allocation of resources and time and lack of training. These systemic issues should be eradicated or minimized during planning. However, there is a lack of detailed planning tools to help managers assess the impact of their upstream decisions on worker safety behavior. Even though simulation had been used in construction planning, the review conducted in this study showed that construction safety management research had not been exploiting the potential of simulation techniques. Thus, a hybrid simulation framework is proposed to facilitate integration of safety management considerations into construction activity simulation. The hybrid framework consists of discrete event simulation (DES) as the core, but heterogeneous, interactive and intelligent (able to make decisions) agents replace traditional entities and resources. In addition, some of the cognitive processes and physiological aspects of agents are captured using system dynamics (SD) approach. The combination of DES, agent-based simulation (ABS) and SD allows a more "natural" representation of the complex dynamics in construction activities. The proposed hybrid framework was demonstrated using a hypothetical case study. In addition, due to the lack of application of factorial experiment approach in safety management simulation, the case study demonstrated sensitivity analysis and factorial experiment to guide future research.

  6. A Hybrid Metaheuristic DE/CS Algorithm for UCAV Three-Dimension Path Planning

    Directory of Open Access Journals (Sweden)

    Gaige Wang

    2012-01-01

    Full Text Available Three-dimension path planning for uninhabited combat air vehicle (UCAV is a complicated high-dimension optimization problem, which primarily centralizes on optimizing the flight route considering the different kinds of constrains under complicated battle field environments. A new hybrid metaheuristic differential evolution (DE and cuckoo search (CS algorithm is proposed to solve the UCAV three-dimension path planning problem. DE is applied to optimize the process of selecting cuckoos of the improved CS model during the process of cuckoo updating in nest. The cuckoos can act as an agent in searching the optimal UCAV path. And then, the UCAV can find the safe path by connecting the chosen nodes of the coordinates while avoiding the threat areas and costing minimum fuel. This new approach can accelerate the global convergence speed while preserving the strong robustness of the basic CS. The realization procedure for this hybrid metaheuristic approach DE/CS is also presented. In order to make the optimized UCAV path more feasible, the B-Spline curve is adopted for smoothing the path. To prove the performance of this proposed hybrid metaheuristic method, it is compared with basic CS algorithm. The experiment shows that the proposed approach is more effective and feasible in UCAV three-dimension path planning than the basic CS model.

  7. A hybrid metaheuristic DE/CS algorithm for UCAV three-dimension path planning.

    Science.gov (United States)

    Wang, Gaige; Guo, Lihong; Duan, Hong; Wang, Heqi; Liu, Luo; Shao, Mingzhen

    2012-01-01

    Three-dimension path planning for uninhabited combat air vehicle (UCAV) is a complicated high-dimension optimization problem, which primarily centralizes on optimizing the flight route considering the different kinds of constrains under complicated battle field environments. A new hybrid metaheuristic differential evolution (DE) and cuckoo search (CS) algorithm is proposed to solve the UCAV three-dimension path planning problem. DE is applied to optimize the process of selecting cuckoos of the improved CS model during the process of cuckoo updating in nest. The cuckoos can act as an agent in searching the optimal UCAV path. And then, the UCAV can find the safe path by connecting the chosen nodes of the coordinates while avoiding the threat areas and costing minimum fuel. This new approach can accelerate the global convergence speed while preserving the strong robustness of the basic CS. The realization procedure for this hybrid metaheuristic approach DE/CS is also presented. In order to make the optimized UCAV path more feasible, the B-Spline curve is adopted for smoothing the path. To prove the performance of this proposed hybrid metaheuristic method, it is compared with basic CS algorithm. The experiment shows that the proposed approach is more effective and feasible in UCAV three-dimension path planning than the basic CS model.

  8. Comparison of the efficiency between two sampling plans for aflatoxins analysis in maize.

    Science.gov (United States)

    Mallmann, Adriano Olnei; Marchioro, Alexandro; Oliveira, Maurício Schneider; Rauber, Ricardo Hummes; Dilkin, Paulo; Mallmann, Carlos Augusto

    2014-01-01

    Variance and performance of two sampling plans for aflatoxins quantification in maize were evaluated. Eight lots of maize were sampled using two plans: manual, using sampling spear for kernels; and automatic, using a continuous flow to collect milled maize. Total variance and sampling, preparation, and analysis variance were determined and compared between plans through multifactor analysis of variance. Four theoretical distribution models were used to compare aflatoxins quantification distributions in eight maize lots. The acceptance and rejection probabilities for a lot under certain aflatoxin concentration were determined using variance and the information on the selected distribution model to build the operational characteristic curves (OC). Sampling and total variance were lower at the automatic plan. The OC curve from the automatic plan reduced both consumer and producer risks in comparison to the manual plan. The automatic plan is more efficient than the manual one because it expresses more accurately the real aflatoxin contamination in maize.

  9. Comparison of the efficiency between two sampling plans for aflatoxins analysis in maize

    Directory of Open Access Journals (Sweden)

    Adriano Olnei Mallmann

    2014-01-01

    Full Text Available Variance and performance of two sampling plans for aflatoxins quantification in maize were evaluated. Eight lots of maize were sampled using two plans: manual, using sampling spear for kernels; and automatic, using a continuous flow to collect milled maize. Total variance and sampling, preparation, and analysis variance were determined and compared between plans through multifactor analysis of variance. Four theoretical distribution models were used to compare aflatoxins quantification distributions in eight maize lots. The acceptance and rejection probabilities for a lot under certain aflatoxin concentration were determined using variance and the information on the selected distribution model to build the operational characteristic curves (OC. Sampling and total variance were lower at the automatic plan. The OC curve from the automatic plan reduced both consumer and producer risks in comparison to the manual plan. The automatic plan is more efficient than the manual one because it expresses more accurately the real aflatoxin contamination in maize.

  10. Hybrid nested sampling algorithm for Bayesian model selection applied to inverse subsurface flow problems

    KAUST Repository

    Elsheikh, Ahmed H.

    2014-02-01

    A Hybrid Nested Sampling (HNS) algorithm is proposed for efficient Bayesian model calibration and prior model selection. The proposed algorithm combines, Nested Sampling (NS) algorithm, Hybrid Monte Carlo (HMC) sampling and gradient estimation using Stochastic Ensemble Method (SEM). NS is an efficient sampling algorithm that can be used for Bayesian calibration and estimating the Bayesian evidence for prior model selection. Nested sampling has the advantage of computational feasibility. Within the nested sampling algorithm, a constrained sampling step is performed. For this step, we utilize HMC to reduce the correlation between successive sampled states. HMC relies on the gradient of the logarithm of the posterior distribution, which we estimate using a stochastic ensemble method based on an ensemble of directional derivatives. SEM only requires forward model runs and the simulator is then used as a black box and no adjoint code is needed. The developed HNS algorithm is successfully applied for Bayesian calibration and prior model selection of several nonlinear subsurface flow problems. © 2013 Elsevier Inc.

  11. Sample preparation and in situ hybridization techniques for automated molecular cytogenetic analysis of white blood cells

    Energy Technology Data Exchange (ETDEWEB)

    Rijke, F.M. van de; Vrolijk, H.; Sloos, W. [Leiden Univ. (Netherlands)] [and others

    1996-06-01

    With the advent in situ hybridization techniques for the analysis of chromosome copy number or structure in interphase cells, the diagnostic and prognostic potential of cytogenetics has been augmented considerably. In theory, the strategies for detection of cytogenetically aberrant cells by in situ hybridization are simple and straightforward. In practice, however, they are fallible, because false classification of hybridization spot number or patterns occurs. When a decision has to be made on molecular cytogenetic normalcy or abnormalcy of a cell sample, the problem of false classification becomes particularly prominent if the fraction of aberrant cells is relatively small. In such mosaic situations, often > 200 cells have to be evaluated to reach a statistical sound figure. The manual enumeration of in situ hybridization spots in many cells in many patient samples is tedious. Assistance in the evaluation process by automation of microscope functions and image analysis techniques is, therefore, strongly indicated. Next to research and development of microscope hardware, camera technology, and image analysis, the optimization of the specimen for the (semi)automated microscopic analysis is essential, since factors such as cell density, thickness, and overlap have dramatic influences on the speed and complexity of the analysis process. Here we describe experiments that have led to a protocol for blood cell specimen that results in microscope preparations that are well suited for automated molecular cytogenetic analysis. 13 refs., 4 figs., 1 tab.

  12. Background Information for the Nevada National Security Site Integrated Sampling Plan, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Farnham, Irene; Marutzky, Sam

    2014-12-01

    This document describes the process followed to develop the Nevada National Security Site (NNSS) Integrated Sampling Plan (referred to herein as the Plan). It provides the Plan’s purpose and objectives, and briefly describes the Underground Test Area (UGTA) Activity, including the conceptual model and regulatory requirements as they pertain to groundwater sampling. Background information on other NNSS groundwater monitoring programs—the Routine Radiological Environmental Monitoring Plan (RREMP) and Community Environmental Monitoring Program (CEMP)—and their integration with the Plan are presented. Descriptions of the evaluations, comments, and responses of two Sampling Plan topical committees are also included.

  13. Hybrid microsystem with functionalized silicon substrate and PDMS sample operating microchannel: A reconfigurable microfluidics scheme

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A hybrid microsystem with separately functioned temperature controlling substrate and sample operating fluidic microchannel was developed to demonstrate a reconfigurable microfluidics scheme.The temperature controlling substrate integrated a micro heater and a temperature sensor by using traditional silicon-based micromechanical system(MEMS)technique,which guaranteed high performance and robust reliability for repeatable usage.The sample operating fluidic microchannel was prepared by poly-(dimethylsiloxane) (PDMS)based soft lithography technique,which made it cheap enough for disposable applications.The PDMS microchannel chip was attached to the temperature controlling substrate for reconfigurable thermal applications.A thin PDMS film was used to seal the microchannel and bridge the functionalized substrate and the sample inside the channel,which facilitated heat transferring and prevented sample contaminating the temperature controlling substrate.Demonstrated by a one dimensional thermal resistance model,the thin PDMS film was important for the present reconfiguration applications.Thermal performance of this hybrid microsystem was examined,and the experimental results demonstrated that the chip system could work stably over hours with temperature variation less than 0.1oC.Multiple PDMS microchannel chips were tested on one heating substrate sequentially with a maximum intra-chip temperature difference of 1.0oC.DNA extracted from serum of a chronic hepatitis B virus(HBV)patient was amplified by this hybrid microsystem and the gel electrophoresis result indicated that the present reconfigurable microfluidic scheme worked successfully.

  14. Comparison of noninvasive sample collection procedures for canine leishmaniasis diagnosis by PCR-hybridization

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Sidney de Almeida; Andrade, Antero Silva Ribeiro de [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)]. E-mail: vidasnino@yahoo.com.br; antero@cdtn.br; Ituassu, Leonardo Trindade; Melo, Maria Norma de [Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil)]. E-mail: melo@mono.icb.ufmg.br; ltituassu@yahoo.com.br

    2007-07-01

    The dogs are the main reservoir of the visceral leishmaniasis etiological agent Leishmania chagasi and these animals have to be systematically monitored. The aim of present work was to standardize a method for canine leishmaniasis diagnosis using DNA samples obtained by a noninvasive ways. Two kind of samples were compared: conjunctival swab and blood. The samples were analyzed by the Polymerase Chain Reaction (PCR) associated with the hybridization of {sup 32}P labeled DNA probes. An in vitro test was carried out using cotton swabs seeded with L. chagasi parasites at different cell numbers. After that, the PCR and hybridization sensitivity was evaluated in two groups of 23 seropositive dogs. Conjunctival swabs and 1,0 mL of blood were collected from each animal. 90 {mu}L of these blood were spotted onto filter paper and the remaining used to prepare the buffy coat. The DNA purification from cotton swabs was carried out through the phenol-chloroform (group 1) or boiling (group 2). The Wizard kit was used to DNA extraction from buffy coat. The filters were treated according to Dialab protocol. The analysis of the seeded samples showed that the PCR was able to identify until ten parasites while the following hybridization of the PCR products allows the detection of until one parasite. The PCR positivity for the conjunctival swabs were 73.9% and 52.2% respectively to the groups 1 and 2. For buffy coat the positivities were 43.5% and 56.5% respectively. The filters presented the lowest positivity. The hybridization step was not accomplished yet for these samples. (author)

  15. Sampling Enrichment toward Target Structures Using Hybrid Molecular Dynamics-Monte Carlo Simulations.

    Science.gov (United States)

    Yang, Kecheng; Różycki, Bartosz; Cui, Fengchao; Shi, Ce; Chen, Wenduo; Li, Yunqi

    2016-01-01

    Sampling enrichment toward a target state, an analogue of the improvement of sampling efficiency (SE), is critical in both the refinement of protein structures and the generation of near-native structure ensembles for the exploration of structure-function relationships. We developed a hybrid molecular dynamics (MD)-Monte Carlo (MC) approach to enrich the sampling toward the target structures. In this approach, the higher SE is achieved by perturbing the conventional MD simulations with a MC structure-acceptance judgment, which is based on the coincidence degree of small angle x-ray scattering (SAXS) intensity profiles between the simulation structures and the target structure. We found that the hybrid simulations could significantly improve SE by making the top-ranked models much closer to the target structures both in the secondary and tertiary structures. Specifically, for the 20 mono-residue peptides, when the initial structures had the root-mean-squared deviation (RMSD) from the target structure smaller than 7 Å, the hybrid MD-MC simulations afforded, on average, 0.83 Å and 1.73 Å in RMSD closer to the target than the parallel MD simulations at 310K and 370K, respectively. Meanwhile, the average SE values are also increased by 13.2% and 15.7%. The enrichment of sampling becomes more significant when the target states are gradually detectable in the MD-MC simulations in comparison with the parallel MD simulations, and provide >200% improvement in SE. We also performed a test of the hybrid MD-MC approach in the real protein system, the results showed that the SE for 3 out of 5 real proteins are improved. Overall, this work presents an efficient way of utilizing solution SAXS to improve protein structure prediction and refinement, as well as the generation of near native structures for function annotation.

  16. A hybrid conformal planning technique with solitary dynamic portal for postmastectomy radiotherapy with regional nodes

    Directory of Open Access Journals (Sweden)

    K Mohamathu Rafic

    2017-01-01

    Full Text Available Purpose: This study focuses on incorporation of a solitary dynamic portal (SDP in conformal planning for postmastectomy radiotherapy (PMRT with nodal regions with an intention to overcome the treatment planning limitations imposed by conventional techniques. Materials and Methods: Twenty-four patients who underwent surgical mastectomy followed by PMRT were included in this study. Initially, a treatment plan comprising tangential beams fitted to beam's-eye-view (BEV of chest wall (CW and a direct anterior field fitted to BEV of nodal region, both sharing a single isocenter was generated using Eclipse treatment planning system. Multiple field-in-fields with optimum beam weights (5% per field were added primarily from the medial tangent, fitted to BEV of entire target volume, and finally converted into a dynamic portal. Dosimetric analysis for the treatment plans and fluence verification for the dynamic portals were performed. Results and Discussion: Conformal plans with SDP showed excellent dose coverage (V95%>95%, higher degree of tumor dose conformity (≤1.25 and homogeneity (≤0.12 without compromising the organ at risk sparing for PMRT with nodal region. Treatment plans with SDP considerably reduced the lower isodose spread to the ipsilateral lung, heart, and healthy tissue without affecting the dose homogeneity. Further, gamma evaluation showed more than 96% pixel pass rate for standard 3%/3 mm dose difference and distance-to-agreement criteria. Moreover, this plan offers less probability of “geometrical miss” at the highly irregular CW with regional nodal radiotherapy. Conclusion: Hybrid conformal plans with SDP would facilitate improved dose distribution and reduced uncertainty in delivery and promises to be a suitable treatment option for complex postmastectomy CW with regional nodal irradiation.

  17. Role of hybrid forecasting techniques for transportation planning of broiler meat under uncertain demand in thailand

    Directory of Open Access Journals (Sweden)

    Thoranin Sujjaviriyasup

    2014-12-01

    Full Text Available One of numerous problems experiencing in supply chain management is the demand. Most demands are appeared in terms of uncertainty. The broiler meat industry is inevitably encountering the same problem. In this research, hybrid forecasting model of ARIMA and Support Vector Machine (SVMs are developed to forecast broiler meat export. In addition, ARIMA, SVMs, and Moving Average (MA are chosen for comparing the forecasting efficiency. All the forecasting models are tested and validated using the data of Brazil’s export, Canada’s export, and Thailand’s export. The hybrid model provides accuracy of the forecasted values that are 98.71%, 97.50%, and 93.01%, respectively. In addition, the hybrid model presents the least error of all MAE, RMSE, and MAPE comparing with other forecasting models. As forecasted data are applied to transportation planning, the mean absolute percentage error (MAPE of optimal value of forecasted value and actual value is 14.53%. The hybrid forecasting model shows an ability to reduce risk of total cost of transportation when broiler meat export is forecasted by using MA(2, MA(3, ARIMA, and SVM are 50.59%, 60.18%, 68.01%, and 46.55%, respectively. The results indicate that the developed forecasting model is recommended to broiler meat industries’ supply chain decision.

  18. 40 CFR 141.802 - Coliform sampling plan.

    Science.gov (United States)

    2010-07-01

    ... Section 141.802 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Aircraft Drinking Water Rule § 141.802 Coliform... also be included in the Aircraft Water System Operations and Maintenance Plan required in § 141.804. ...

  19. Wildlife Conservation Planning Using Stochastic Optimization and Importance Sampling

    Science.gov (United States)

    Robert G. Haight; Laurel E. Travis

    1997-01-01

    Formulations for determining conservation plans for sensitive wildlife species must account for economic costs of habitat protection and uncertainties about how wildlife populations will respond. This paper describes such a formulation and addresses the computational challenge of solving it. The problem is to determine the cost-efficient level of habitat protection...

  20. Standardized Sampling Plan for the Thrips Frankliniella schultzei (Thysanoptera: Thripidae) on Watermelon Crops.

    Science.gov (United States)

    Barbosa Pinto, Cleovan; Almeida Sarmento, Renato; Visintin da Silva Galdino, Tarcísio; Silvestre Pereira, Poliana; Gomes Barbosa, Breno; Henrique Oliveira Lima, Carlos; Rodrigues da Silva, Nilson; Coutinho Picanço, Marcelo

    2017-04-01

    Sampling plans are essential components of integrated pest management programs. The thrips Frankliniella schultzei (Trybom) (Thysanoptera: Thripidae) is an important pest of watermelon crops. Despite the importance of sampling plans and of F. schultzei as a pest of watermelon crops, no research has been previously conducted on this subject for this crop. The objective of this work was to create a standardized sampling plan for F. schultzei in watermelon crops. Over two consecutive years, weekly samplings were performed in commercial watermelon crops. The aim of these assessments was to select the best sampling unit and the best sampling technique for F. schultzei assessment and to determine the number of samples necessary for a standardized sampling plan for this pest. In watermelon crops in the vegetative, flowering, and fruiting stages, the ideal location for sampling F. schultzei was the most apical leaf of the branches. The best sampling technique was a direct count of F. schultzei individuals. The F. schultzei sampling plan involved the evaluation of 69 samples per plot. The execution duration of this sampling plan in 1- to 15-ha plots was sampling). This has not been reported for watermelon before. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. An integrated hybrid system for genetic analysis combining EWOD sample preparation and magnetic detection

    Energy Technology Data Exchange (ETDEWEB)

    Brennan, Des; Dinca, Mihai; Aherne, Margaret; Galvin, Paul [Tyndall National Institute, University College, Cork, Lee Maltings, Prospect Row, Cork (Ireland); Jary, Dorothee; Peponnet, Christine [CEA-LETI, Department of Technology for Biology and Health, 17 Avenue Des Martyrs, 38054 Grenoble (France); Cardosa, Filipe; Freitas, Paolo, E-mail: des.brennan@tyndall.ie [INESC-MN, Rua Alves Redol, 9, 1000-029 Lisbon (Portugal)

    2011-08-17

    Over the last decade microelectronic technologies have delivered significant advances in devices for point of care diagnostics. Complex microfluidic systems integrate components such as valves, pumps etc. to manipulate liquids. In recent years, the drive is to combine biochemical protocols in a single system, delivering 'sample in answer out'. An Electrowetting on Dielectric (EWOD) device offers the possibility to move and manipulate 64nl volumes implementing biochemical processes, while the magnetic sensor facilitates hybridisation detection. We outline an injection molding approach where EWOD and magnetic devices are integrated into a hybrid microfluidic system with the potential to implement 'sample in answer out' biological protocols.

  2. An integrated hybrid system for genetic analysis combining EWOD sample preparation and magnetic detection

    Science.gov (United States)

    Brennan, Des; Jary, Dorothee; Peponnet, Christine; Cardosa, Filipe; Freitas, Paolo; Dinca, Mihai; Aherne, Margaret; Galvin, Paul

    2011-08-01

    Over the last decade microelectronic technologies have delivered significant advances in devices for point of care diagnostics. Complex microfluidic systems integrate components such as valves, pumps etc. to manipulate liquids. In recent years, the drive is to combine biochemical protocols in a single system, delivering "sample in answer out". An Electrowetting on Dielectric (EWOD) device offers the possibility to move and manipulate 64nl volumes implementing biochemical processes, while the magnetic sensor facilitates hybridisation detection. We outline an injection molding approach where EWOD and magnetic devices are integrated into a hybrid microfluidic system with the potential to implement "sample in answer out" biological protocols.

  3. Motion Planning Using an Impact-Based Hybrid Control for Trajectory Generation in Adaptive Walking

    Directory of Open Access Journals (Sweden)

    Umar Asif

    2011-09-01

    Full Text Available This paper aims to solve a major drawback of walking robots i.e. their inability to react to environmental disturbances while navigating in natural rough terrains. This problem is reduced here by suggesting the use of a hybrid force‐position control based trajectory generation with the impact dynamics into consideration that compensates for the stability variations, thus helping the robot react stably in the face of environmental disturbances. As a consequence, the proposed impact‐based hybrid control helps the robot achieve better and stable motion planning than conventional position‐based control algorithms. Dynamic simulations and real world outdoor experiments performed on a six legged hexapod robot show a relevant improvement in the robot locomotion.

  4. PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples

    DEFF Research Database (Denmark)

    Fazli, Mustafa; Bjarnsholt, Thomas; Høiby, Niels;

    2014-01-01

    Fluorescence in situ hybridization with PNA probes (PNA-FISH) that target specific bacterial ribosomal RNA sequences is a powerful and rapid tool for identification of bacteria in clinical samples. PNA can diffuse readily through the bacterial cell wall due to its uncharged backbone, and PNA-FISH....... In all these cases, bacteria can be identified in biofilm aggregates, which may explain their recalcitrance to antibiotic treatment.......Fluorescence in situ hybridization with PNA probes (PNA-FISH) that target specific bacterial ribosomal RNA sequences is a powerful and rapid tool for identification of bacteria in clinical samples. PNA can diffuse readily through the bacterial cell wall due to its uncharged backbone, and PNA......-FISH can be performed with high specificity due to the extraordinary thermal stability of RNA-PNA hybrid complexes. We describe a PNA-FISH procedure and provide examples of the application of PNA-FISH for the identification of bacteria in chronic wounds, cystic fibrosis lungs, and soft tissue fillers...

  5. A hybrid strategy of offline adaptive planning and online image guidance for prostate cancer radiotherapy

    Science.gov (United States)

    Lei, Yu; Wu, Qiuwen

    2010-04-01

    Offline adaptive radiotherapy (ART) has been used to effectively correct and compensate for prostate motion and reduce the required margin. The efficacy depends on the characteristics of the patient setup error and interfraction motion through the whole treatment; specifically, systematic errors are corrected and random errors are compensated for through the margins. In online image-guided radiation therapy (IGRT) of prostate cancer, the translational setup error and inter-fractional prostate motion are corrected through pre-treatment imaging and couch correction at each fraction. However, the rotation and deformation of the target are not corrected and only accounted for with margins in treatment planning. The purpose of this study was to investigate whether the offline ART strategy is necessary for an online IGRT protocol and to evaluate the benefit of the hybrid strategy. First, to investigate the rationale of the hybrid strategy, 592 cone-beam-computed tomography (CBCT) images taken before and after each fraction for an online IGRT protocol from 16 patients were analyzed. Specifically, the characteristics of prostate rotation were analyzed. It was found that there exist systematic inter-fractional prostate rotations, and they are patient specific. These rotations, if not corrected, are persistent through the treatment fraction, and rotations detected in early fractions are representative of those in later fractions. These findings suggest that the offline adaptive replanning strategy is beneficial to the online IGRT protocol with further margin reductions. Second, to quantitatively evaluate the benefit of the hybrid strategy, 412 repeated helical CT scans from 25 patients during the course of treatment were included in the replanning study. Both low-risk patients (LRP, clinical target volume, CTV = prostate) and intermediate-risk patients (IRP, CTV = prostate + seminal vesicles) were included in the simulation. The contours of prostate and seminal vesicles were

  6. A hybrid strategy of offline adaptive planning and online image guidance for prostate cancer radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Lei Yu [Department of Radiation Oncology, Wayne State University, 4100 John R, Detroit, MI 48201 (United States); Wu Qiuwen [Department of Radiation Oncology, William Beaumont Hospital, 3601 West 13 Mile Rd, Royal Oak, MI 48073 (United States)], E-mail: Qiuwen.Wu@Duke.edu

    2010-04-21

    Offline adaptive radiotherapy (ART) has been used to effectively correct and compensate for prostate motion and reduce the required margin. The efficacy depends on the characteristics of the patient setup error and interfraction motion through the whole treatment; specifically, systematic errors are corrected and random errors are compensated for through the margins. In online image-guided radiation therapy (IGRT) of prostate cancer, the translational setup error and inter-fractional prostate motion are corrected through pre-treatment imaging and couch correction at each fraction. However, the rotation and deformation of the target are not corrected and only accounted for with margins in treatment planning. The purpose of this study was to investigate whether the offline ART strategy is necessary for an online IGRT protocol and to evaluate the benefit of the hybrid strategy. First, to investigate the rationale of the hybrid strategy, 592 cone-beam-computed tomography (CBCT) images taken before and after each fraction for an online IGRT protocol from 16 patients were analyzed. Specifically, the characteristics of prostate rotation were analyzed. It was found that there exist systematic inter-fractional prostate rotations, and they are patient specific. These rotations, if not corrected, are persistent through the treatment fraction, and rotations detected in early fractions are representative of those in later fractions. These findings suggest that the offline adaptive replanning strategy is beneficial to the online IGRT protocol with further margin reductions. Second, to quantitatively evaluate the benefit of the hybrid strategy, 412 repeated helical CT scans from 25 patients during the course of treatment were included in the replanning study. Both low-risk patients (LRP, clinical target volume, CTV = prostate) and intermediate-risk patients (IRP, CTV = prostate + seminal vesicles) were included in the simulation. The contours of prostate and seminal vesicles were

  7. Hybrid Heuristic Online Planning for POMDPs%杂合启发式在线POMDP规划*

    Institute of Scientific and Technical Information of China (English)

    章宗长; 陈小平

    2013-01-01

    Lots of planning tasks of autonomous robots under uncertain environments can be modeled as a partially observable Markov decision processes (POMDPs). Although researchers have made impressive progress in designing approximation techniques, developing an efficient planning algorithm for POMDPs is still considered as a challenging problem. Previous research has indicated that online planning approaches are promising approximate methods for handling large-scale POMDP domains efficiently as they make decisions“on demand”, instead of proactively for the entire state space. This paper aims to further speed up the POMDP online planning process by designing a novel hybrid heuristic function, which provides a feasible way to take full advantage of some ignored heuristics in current algorithms. The research implements a new method called hybrid heuristic online planning (HHOP). HHOP substantially outperformes state-of-the-art online heuristic search approaches on a suite of POMDP benchmark problems.%  许多不确定环境下的自主机器人规划任务都可以用部分可观察的马氏决策过程(partially observable Markov decision process,简称POMDP)建模。尽管研究者们在近似求解技术的设计方面已经取得了显著的进展,开发高效的 POMDP 规划算法依然是一个具有挑战性的问题。以前的研究结果表明:在线规划方法能够高效地处理大规模的 POMDP 问题,因而是一类具有研究前景的近似求解方法。这归因于它们采取的是“按需”作决策而不是预前对整个状态空间作决策的方式。旨在通过设计一个新颖的杂合启发式函数来进一步加速 POMDP 在线规划过程,该函数能够充分利用现有算法里一些被忽略掉的启发式信息。实现了一个新的杂合启发式在线规划(hybrid heuristic online planning,简称HHOP)算法。在一组POMDP基准问题上,HHOP有明显优于现有在线启发式搜索算法的实验性能。

  8. Determination of Optimal Double Sampling Plan using Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Sampath Sundaram

    2012-03-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Designing double sampling plan requires identification of sample sizes and acceptance numbers. In this paper a genetic algorithm has been designed for the selection of optimal acceptance numbers and sample sizes for the specified producer’s risk and consumer’s risk. Implementation of the algorithm has been illustrated numerically for different choices of quantities involved in a double sampling plan   

  1. Feasible sampling plan for Bemisia tabaci control decision-making in watermelon fields.

    Science.gov (United States)

    Lima, Carlos Ho; Sarmento, Renato A; Pereira, Poliana S; Galdino, Tarcísio Vs; Santos, Fábio A; Silva, Joedna; Picanço, Marcelo C

    2017-05-23

    The silverleaf whitefly Bemisia tabaci is one of the most important pests of watermelon fields worldwide. Conventional sampling plans are the starting point for the generation of decision-making systems of integrated pest management programs. The aim of this study was to determine a conventional sampling plan for B. tabaci in watermelon fields. The optimal leaf for B. tabaci adult sampling was the 6(th) most apical leaf. Direct counting was the best pest sampling technique. Crop pest densities fitted the negative binomial distribution and had a common aggregation parameter (Kcommon ). The sampling plan consisted of evaluating 103 samples per plot. This sampling plan was conducted for 56 min, costing US$ 2.22 per sampling and with a 10% maximum evaluation error. The sampling plan determined in this study can be adopted by farmers because it enables the adequate evaluation of B. tabaci populations in watermelon fields (10% maximum evaluation error) and is a low-cost (US$ 2.22 per sampling), fast (56 min per sampling) and feasible (because it may be used in a standardized way throughout the crop cycle) technique. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  2. Adapting sampling plans to caribou distribution on calving grounds

    Directory of Open Access Journals (Sweden)

    Michel Crête

    1991-10-01

    Full Text Available Between 1984 and 1988, the size of the two caribou herds in northern Québec was derived by combining estimates of female numbers on calving grounds in June and composition counts during rut in autumn. Sampling with aerial photos was conducted on calving grounds to determine the number of animals per km2, telemetry served to estimate the proportion of females in the census area at the time of photography in addition to summer survival rate, and helicopter or ground observations were used for composition counts. Observers were able to detect on black and white negatives over 95 percent of caribou counted from a helicopter flying at low altitude over the same area; photo scale varied between = 1:3 600 and 1:6 000. Sampling units covering less than 15-20 ha were the best for sampling caribou distribution on calving grounds, where density generally averaged » 10 individuals-km"2. Around 90 percent of caribou on calving grounds were females; others were mostly yearling males. During the 1-2 day photographic census, 64 to 77 percent of the females were present on the calving areas. Summer survival exceeded 95 percent in three summers. In autumn, females composed between 45 and 54 percent of each herd. The Rivière George herd was estimated at 682 000 individuals (± 36%; alpha = 0.10 in 1988. This estimate was imprecise due to insufficiens sample size for measuring animal density on the calving ground and for determining proportion of females on the calving ground at the time of the photo census. To improve precision and reduce cost, it is proposed to estimate herd size of tundra caribou in one step, using only aerial photos in early June without telemetry.

  3. Waste sampling and characterization facility (WSCF) maintenance implementation plan

    Energy Technology Data Exchange (ETDEWEB)

    Heinemann, J.L.

    1997-08-13

    This Maintenance Implementation Plan (MIP) is written to satisfy the requirements of the US Department of Energy (DOE) Order 4330.4B, Maintenance Management Program that specifies the general policy and objectives for the establishment of the DOE controlled maintenance programs. These programs provide for the management and performance of cost effective maintenance and repair of the DOE property, which includes facilities. This document outlines maintenance activities associated with the facilities operated by Waste Management Hanford, Inc. (WMH). The objective of this MIP is to provide baseline information for the control and execution of WMH Facility Maintenance activities relative to the requirements of Order 4330.4B, assessment of the WMH maintenance programs, and actions necessary to maintain compliance with the Order. Section 2.0 summarizes the history, mission and description of the WMH facilities. Section 3.0 describes maintenance scope and requirements, and outlines the overall strategy for implementing the maintenance program. Specific elements of DOE Order 4330.4B are addressed in Section 4.0, listing the objective of each element, a discussion of the WMH compliance methodology, and current implementation requirements with references to WMH and HNF policies and procedures. Section 5.0 addresses deviations from policy requirements, and Section 6.0 is a schedule for specific improvements in support of this MIP.

  4. Evaluation of Sampling Methods and Development of Sample Plans for Estimating Predator Densities in Cotton

    Science.gov (United States)

    The cost-reliability of five sampling methods (visual search, drop cloth, beat bucket, shake bucket and sweep net) was determined for predatory arthropods on cotton plants. The beat bucket sample method was the most cost-reliable while the visual sample method was the least cost-reliable. The beat ...

  5. Analysis of sampling plan options for tank 16H from the perspective of statistical uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Shine, E. P.

    2013-02-28

    This report develops a concentration variability model for Tank 16H in order to compare candidate sampling plans for assessing the concentrations of analytes in the residual material in the annulus and on the floor of the primary vessel. A concentration variability model is used to compare candidate sampling plans based on the expected upper 95% confidence limit (UCL95) for the mean. The result is expressed as a rank order of candidate sampling plans from lowest to highest expected UCL95, with the lowest being the most desirable from an uncertainty perspective.

  6. Tank 241-AZ-102 Privatization Push Mode Core Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    TEMPLETON, A.M.

    1999-07-08

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AZ-102. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AZ-102. Push mode core samples will be obtained from risers 15C and 24A to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples, composite the liquids and solids, perform chemical analyses, and provide subsamples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AZ-102 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plan.

  7. UMTRA project water sampling and analysis plan, Durango, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    Surface remedial action has been completed at the Uranium Mill Tailings Remedial Action Project in Durango, Colorado. Contaminated soil and debris have been removed from the former processing site and placed in the Bodo Canyon disposal cell. Ground water at the former uranium mill/tailings site and raffinate pond area has been contaminated by the former milling operations. The ground water at the disposal site was not impacted by the former milling operations at the time of the cell`s construction. Activities for fiscal 1994 involve ground water sampling and site characterization of the disposal site.

  8. UMTRA project water sampling and analysis plan, Riverton, Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    Surface remediation was completed at the former uranium mill site in Riverton, Wyoming, in 1990. Residual radioactive materials (contaminated soil and debris) were removed and disposed of at Union Carbide Corporation`s (Umetco) nearby Gas Hills Title 2 facility. Ground water in the surficial and semiconfined aquifers (known collectively as the `uppermost aquifer`) below the former mill and tailings site has been contaminated. No contamination has been detected in the deeper, confined sandstone aquifer. The contaminant plume extends off site to the south and east. The plume is constrained by surface wetlands and small streams to the east and west of the site and by the Little Wind River to the south. Fifteen monitor wells installed in 1993 were sampled to better define the contaminant plume and to provide additional water quality data for the baseline risk assessment. Samples also were collected from domestic wells in response to a request by the Wyoming Department of Environmental Quality in January 1994. No contamination attributable to the former uranium milling operations have ever been detected in any of the domestic wells used for potable supplies.

  9. A Hybrid System of Hierarchical Planning of Behaviour Selection Networks for Mobile Robot Control

    Directory of Open Access Journals (Sweden)

    Young-Seol Lee

    2014-04-01

    Full Text Available An office delivery robot receives a large amount of sensory data and there is uncertainty in its action outcomes. The robot should not only accomplish its goals using environmental information, but also consider various exceptions simultaneously. In this paper, we propose a hybrid system using hierarchical planning of modular behaviour selection networks to generate autonomous behaviour in the office delivery robot. Behaviour selection networks, one of the well-known behaviour-based methods suitable for goal-oriented tasks, are made up of several smaller behaviour modules. Planning is attached to the construct and adjust sequences of the modules by considering the sub-goals, the priority in each task and the user feedback. This helps the robot to quickly react in dynamic situations as well as achieve global goals efficiently. The proposed system is verified with both the Webot simulator and a Khepera II robot that runs in a real office environment carrying out delivery tasks. Experimental results have shown that a robot can achieve goals and generate module sequences successfully even in unpredictable situations. Additionally, the proposed planning method reduced the elapsed time during tasks by 17.5% since it adjusts the behaviour module sequences more effectively.

  10. Developing optimum sample size and multistage sampling plans for Lobesia botrana (Lepidoptera: Tortricidae) larval infestation and injury in northern Greece.

    Science.gov (United States)

    Ifoulis, A A; Savopoulou-Soultani, M

    2006-10-01

    The purpose of this research was to quantify the spatial pattern and develop a sampling program for larvae of Lobesia botrana Denis and Schiffermüller (Lepidoptera: Tortricidae), an important vineyard pest in northern Greece. Taylor's power law and Iwao's patchiness regression were used to model the relationship between the mean and the variance of larval counts. Analysis of covariance was carried out, separately for infestation and injury, with combined second and third generation data, for vine and half-vine sample units. Common regression coefficients were estimated to permit use of the sampling plan over a wide range of conditions. Optimum sample sizes for infestation and injury, at three levels of precision, were developed. An investigation of a multistage sampling plan with a nested analysis of variance showed that if the goal of sampling is focusing on larval infestation, three grape clusters should be sampled in a half-vine; if the goal of sampling is focusing on injury, then two grape clusters per half-vine are recommended.

  11. Rocky Mountain Arsenal National Wildlife Refuge sampling and analysis plan : bison pesticide residue study

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this Sampling and Analysis Plan (SAP) is to demonstrate that dieldrin concentrations in bison tissues from the Rocky Mountain Arsenal National...

  12. Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-10-24

    This plan incorporates U.S. Department of Energy (DOE) Office of Legacy Management (LM) standard operating procedures (SOPs) into environmental monitoring activities and will be implemented at all sites managed by LM. This document provides detailed procedures for the field sampling teams so that samples are collected in a consistent and technically defensible manner. Site-specific plans (e.g., long-term surveillance and maintenance plans, environmental monitoring plans) document background information and establish the basis for sampling and monitoring activities. Information will be included in site-specific tabbed sections to this plan, which identify sample locations, sample frequencies, types of samples, field measurements, and associated analytes for each site. Additionally, within each tabbed section, program directives will be included, when developed, to establish additional site-specific requirements to modify or clarify requirements in this plan as they apply to the corresponding site. A flowchart detailing project tasks required to accomplish routine sampling is displayed in Figure 1. LM environmental procedures are contained in the Environmental Procedures Catalog (LMS/PRO/S04325), which incorporates American Society for Testing and Materials (ASTM), DOE, and U.S. Environmental Protection Agency (EPA) guidance. Specific procedures used for groundwater and surface water monitoring are included in Appendix A. If other environmental media are monitored, SOPs used for air, soil/sediment, and biota monitoring can be found in the site-specific tabbed sections in Appendix D or in site-specific documents. The procedures in the Environmental Procedures Catalog are intended as general guidance and require additional detail from planning documents in order to be complete; the following sections fulfill that function and specify additional procedural requirements to form SOPs. Routine revision of this Sampling and Analysis Plan will be conducted annually at the

  13. Remedial investigation sampling and analysis plan for J-Field, Aberdeen Proving Ground, Maryland. Volume 1: Field Sampling Plan

    Energy Technology Data Exchange (ETDEWEB)

    Benioff, P.; Biang, R.; Dolak, D.; Dunn, C.; Martino, L.; Patton, T.; Wang, Y.; Yuen, C.

    1995-03-01

    The Environmental Management Division (EMD) of Aberdeen Proving Ground (APG), Maryland, is conducting a remedial investigation and feasibility study (RI/FS) of the J-Field area at APG pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. J-Field is within the Edgewood Area of APG in Harford County, Maryland (Figure 1. 1). Since World War II activities in the Edgewood Area have included the development, manufacture, testing, and destruction of chemical agents and munitions. These materials were destroyed at J-Field by open burning and open detonation (OB/OD). Considerable archival information about J-Field exists as a result of efforts by APG staff to characterize the hazards associated with the site. Contamination of J-Field was first detected during an environmental survey of the Edgewood Area conducted in 1977 and 1978 by the US Army Toxic and Hazardous Materials Agency (USATHAMA) (predecessor to the US Army Environmental Center [AEC]). As part of a subsequent USATHAMA -environmental survey, 11 wells were installed and sampled at J-Field. Contamination at J-Field was also detected during a munitions disposal survey conducted by Princeton Aqua Science in 1983. The Princeton Aqua Science investigation involved the installation and sampling of nine wells and the collection and analysis of surficial and deep composite soil samples. In 1986, a Resource Conservation and Recovery Act (RCRA) permit (MD3-21-002-1355) requiring a basewide RCRA Facility Assessment (RFA) and a hydrogeologic assessment of J-Field was issued by the US Environmental Protection Agency (EPA). In 1987, the US Geological Survey (USGS) began a two-phased hydrogeologic assessment in data were collected to model, groundwater flow at J-Field. Soil gas investigations were conducted, several well clusters were installed, a groundwater flow model was developed, and groundwater and surface water monitoring programs were established that continue today.

  14. Real-time assessment of hybridization between wolves and dogs: combining noninvasive samples with ancestry informative markers.

    Science.gov (United States)

    Godinho, Raquel; López-Bao, José Vicente; Castro, Diana; Llaneza, Luís; Lopes, Susana; Silva, Pedro; Ferrand, Nuno

    2015-03-01

    Wolves and dogs provide a paradigmatic example of the ecological and conservation implications of hybridization events between wild and domesticated forms. However, our understanding of such implications has been traditionally hampered by both high genetic similarity and the difficulties in obtaining tissue samples (TS), which limit our ability to assess ongoing hybridization events. To assess the occurrence and extension of hybridization in a pack of wolf-dog hybrids in northwestern Iberia, we compared the power of 52 nuclear markers implemented on TS with a subset of 13 ancestry informative markers (AIMs) typed in noninvasive samples (NIS). We demonstrate that the 13 AIMs are as accurate as the 52 markers that were chosen without regard to the power to differentiate between wolves and dogs, also having the advantage of being rapidly screened on NIS. The efficiency of AIMs significantly outperformed ten random sets of similar size and an additional commercial set of 18 markers. Bayesian clustering analysis implemented on AIMs and NIS identified nine hybrids, two wolves and two dogs. Four hybrids were unambiguously assigned to F1xWolf backcrosses. Our approach (AIMs + NIS) overcomes previous difficulties related to sample availability and informative power of markers, allowing a quick identification of wolf-dog hybrids in the first phases of hybridization episodes. This provides managers with a reliable tool to evaluate hybridization and estimate the success of their actions. This approach may be easily adapted for other pairs of wild/domesticated species, thus improving our understanding of the introgression of domestication genes into natural populations. © 2014 John Wiley & Sons Ltd.

  15. Spatial Distribution and Sampling Plans for Grapevine Plant Canopy-Inhabiting Scaphoideus titanus (Hemiptera: Cicadellidae) Nymphs.

    Science.gov (United States)

    Rigamonti, Ivo E; Brambilla, Carla; Colleoni, Emanuele; Jermini, Mauro; Trivellone, Valeria; Baumgärtner, Johann

    2016-04-01

    The paper deals with the study of the spatial distribution and the design of sampling plans for estimating nymph densities of the grape leafhopper Scaphoideus titanus Ball in vine plant canopies. In a reference vineyard sampled for model parameterization, leaf samples were repeatedly taken according to a multistage, stratified, random sampling procedure, and data were subjected to an ANOVA. There were no significant differences in density neither among the strata within the vineyard nor between the two strata with basal and apical leaves. The significant differences between densities on trunk and productive shoots led to the adoption of two-stage (leaves and plants) and three-stage (leaves, shoots, and plants) sampling plans for trunk shoots- and productive shoots-inhabiting individuals, respectively. The mean crowding to mean relationship used to analyze the nymphs spatial distribution revealed aggregated distributions. In both the enumerative and the sequential enumerative sampling plans, the number of leaves of trunk shoots, and of leaves and shoots of productive shoots, was kept constant while the number of plants varied. In additional vineyards data were collected and used to test the applicability of the distribution model and the sampling plans. The tests confirmed the applicability 1) of the mean crowding to mean regression model on the plant and leaf stages for representing trunk shoot-inhabiting distributions, and on the plant, shoot, and leaf stages for productive shoot-inhabiting nymphs, 2) of the enumerative sampling plan, and 3) of the sequential enumerative sampling plan. In general, sequential enumerative sampling was more cost efficient than enumerative sampling.

  16. Generation expansion planning in Pool market: A hybrid modified game theory and particle swarm optimization

    Energy Technology Data Exchange (ETDEWEB)

    Moghddas-Tafreshi, S.M. [Department of Electrical Engineering, K.N. Toosi University of Technology, Tehran (Iran, Islamic Republic of); Shayanfar, H.A. [Center of Excellence for Power System Automation and Operation, Department of Electrical Engineering, Iran University of Science and Technology, Tehran (Iran, Islamic Republic of); Saliminia Lahiji, A. [Department of Electrical Engineering, K.N. Toosi University of Technology, Tehran (Iran, Islamic Republic of); Rabiee, A. [Center of Excellence for Power System Automation and Operation, Department of Electrical Engineering, Iran University of Science and Technology, Tehran (Iran, Islamic Republic of); Aghaei, J., E-mail: aghaei@iust.ac.i [Department of Electrical and Electronic Engineering, Shiraz University of Technology, Shiraz (Iran, Islamic Republic of)

    2011-02-15

    Unlike the traditional policy, Generation Expansion Planning (GEP) problem in competitive framework is complicated. In the new policy, each GENeration COmpany (GENCO) decides to invest in such a way that obtains as much profit as possible. This paper presents a new hybrid algorithm to determine GEP in a Pool market. The proposed algorithm is divided in two programming levels: master and slave. In the master level a modified game theory (MGT) is proposed to evaluate the contrast of GENCOs by the Independent System Operator (ISO). In the slave level, a particle swarm optimization (PSO) method is used to find the best solution of each GENCO for decision-making of investment. The validity of the proposed method is examined in the case study including three GENCOs with multi-types of power plants. The results show that the presented method is both satisfactory and consistent with expectation.

  17. Generation Expansion Planning in pool market: A hybrid modified game theory and improved genetic algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Shayanfar, H.A.; Lahiji, A. Saliminia; Aghaei, J.; Rabiee, A. [Center of Excellence for Power System Automation and Operation, Electrical Engineering Department, Iran University of Science and Technology (IUST), Tehran (Iran)

    2009-05-15

    Unlike the traditional policy, Generation Expansion Planning (GEP) problem in competitive framework is complicated. In the new policy, each Generation Company (GENCO) decides to invest in such a way that obtains as much profit as possible. This paper presents a new hybrid algorithm to determine GEP in a Pool market. The proposed algorithm is divided in two programming levels: master and slave. In the master level a Modified Game Theory (MGT) is proposed to evaluate the contrast of GENCOs by the Independent System Operator (ISO). In the slave level, an Improved Genetic Algorithm (IGA) method is used to find the best solution of each GENCO for decision-making of investment. The validity of the proposed method is examined in the case study including three GENCOs with multi-type of power plants. The results show that the presented method is both satisfactory and consistent with expectation. (author)

  18. A holistic approach towards optimal planning of hybrid renewable energy systems: Combining hydroelectric and wind energy

    Science.gov (United States)

    Dimas, Panagiotis; Bouziotas, Dimitris; Efstratiadis, Andreas; Koutsoyiannis, Demetris

    2014-05-01

    Hydropower with pumped storage is a proven technology with very high efficiency that offers a unique large-scale energy buffer. Energy storage is employed by pumping water upstream to take advantage of the excess of produced energy (e.g. during night) and next retrieving this water to generate hydro-power during demand peaks. Excess energy occurs due to other renewables (wind, solar) whose power fluctuates in an uncontrollable manner. By integrating these with hydroelectric plants with pumped storage facilities we can form autonomous hybrid renewable energy systems. The optimal planning and management thereof requires a holistic approach, where uncertainty is properly represented. In this context, a novel framework is proposed, based on stochastic simulation and optimization. This is tested in an existing hydrosystem of Greece, considering its combined operation with a hypothetical wind power system, for which we seek the optimal design to ensure the most beneficial performance of the overall scheme.

  19. Planning Considerations Related to Collecting and Analyzing Samples of the Martian Soils

    Science.gov (United States)

    Liu, Yang; Mellon, Mike T.; Ming, Douglas W.; Morris, Richard V.; Noble, Sarah K.; Sullivan, Robert J.; Taylor, Lawrence A.; Beaty, David W.

    2014-01-01

    The Mars Sample Return (MSR) End-to-End International Science Analysis Group (E2E-iSAG [1]) established scientific objectives associ-ated with Mars returned-sample science that require the return and investigation of one or more soil samples. Soil is defined here as loose, unconsolidated materials with no implication for the presence or absence of or-ganic components. The proposed Mars 2020 (M-2020) rover is likely to collect and cache soil in addition to rock samples [2], which could be followed by future sample retrieval and return missions. Here we discuss key scientific consid-erations for sampling and caching soil samples on the proposed M-2020 rover, as well as the state in which samples would need to be preserved when received by analysts on Earth. We are seeking feedback on these draft plans as input to mission requirement formulation. A related planning exercise on rocks is reported in an accompanying abstract [3].

  20. A Hybrid Monte Carlo Sampling Filter for Non-Gaussian Data Assimilation

    Directory of Open Access Journals (Sweden)

    Adrian Sandu

    2015-12-01

    Full Text Available Data assimilation combines information from models, measurements, and priors to obtain improved estimates of the state of a dynamical system such as the atmosphere. Ensemble-based data assimilation approaches such as the Ensemble Kalman filter (EnKF have gained wide popularity due to their simple formulation, ease of implementation, and good practical results. Many of these methods are derived under the assumption that the underlying probability distributions are Gaussian. It is well accepted, however, that the Gaussianity assumption is too restrictive when applied to large nonlinear models, nonlinear observation operators, and large levels of uncertainty. When the Gaussianity assumptions are severely violated, the performance of EnKF variations degrades. This paper proposes a new ensemble-based data assimilation method, named the sampling filter, which obtains the analysis by sampling directly from the posterior distribution. The sampling strategy is based on a Hybrid Monte Carlo (HMC approach that can handle non-Gaussian probability distributions. Numerical experiments are carried out using the Lorenz-96 model and observation operators with different levels of non-linearity and differentiability. The proposed filter is also tested with shallow water model on a sphere with linear observation operator. Numerical results show that the sampling filter performs well even in highly nonlinear situations where the traditional filters diverge.

  1. A polynomial hybrid reflection model and measurement of its parameters based on images of sample

    Institute of Scientific and Technical Information of China (English)

    Lei Yang; Jiuqiang Han

    2007-01-01

    Reflectance model is a basic concept in computer vision. Some existing models combining the classical diffuse reflectance model and those for surfaces containing specular components can approximately describe real reflectance. But the ratio of diffuse and specular reflection decided manually has no clear meaning.We propose a new polynomial hybrid reflectance model. The reflectance map equation with a known shape (for example cylinder) as a sample is used to estimate parameters of the proposed reflectance model by least square regression algorithm. Then the reflectance parameters for surfaces of the same class of materials can be determined. Experiments are performed for a metal surface. The synthesis images produced by the proposed method and existing ones are compared with the real acquired image, and the results show that the proposed reflectance model is suitable for describing real reflectance.

  2. Demonstration Report for Visual Sample Plan (VSP) Verification Sampling Methods at the Navy/DRI Site

    Science.gov (United States)

    2011-08-01

    time kinematic ( RTK ) global positioning system ( GPS ) performed anomaly reacquisition. The procedure for reacquiring the location of the anomalies was...load the target anomalies onto the RTK GPS positioning system in the correct format, and 3. place a non-metallic pin flag marked with the unique...Demonstrate the utility of the PRV sampling modules and gain regulator acceptance

  3. Sampling and analysis plan for the former Atomic Energy Commission bus lot property

    Energy Technology Data Exchange (ETDEWEB)

    Nielson, R.R.

    1998-07-01

    This sampling and analysis plan (SAP) presents the rationale and strategy for the sampling and analysis activities proposed in support of an initial investigation of the former Atomic Energy Commission (AEC) bus lot property currently owned by Battelle Memorial Institute. The purpose of the proposed sampling and analysis activity is to investigate the potential for contamination above established action levels. The SAP will provide defensible data of sufficient quality and quantity to support recommendations of whether any further action within the study area is warranted. To assist in preparing sampling plans and reports, the Washington State Department of Ecology (Ecology) has published Guidance on Sampling and Data Analysis Methods. To specifically address sampling plans for petroleum-contaminated sites, Ecology has also published Guidance for Remediation of Petroleum Contaminated Sites. Both documents were used as guidance in preparing this plan. In 1992, a soil sample was taken within the current study area as part of a project to remove two underground storage tanks (USTs) at Battelle`s Sixth Street Warehouse Petroleum Dispensing Station (Section 1.3). The results showed that the sample contained elevated levels of total petroleum hydrocarbons (TPH) in the heavy distillate range. This current study was initiated in part as a result of that discovery. The following topics are considered: the historical background of the site, current site conditions, previous investigations performed at the site, an evaluation based on the available data, and the contaminants of potential concern (COPC).

  4. Reachable Distance Space: Efficient Sampling-Based Planning for Spatially Constrained Systems

    KAUST Repository

    Xinyu Tang,

    2010-01-25

    Motion planning for spatially constrained robots is difficult due to additional constraints placed on the robot, such as closure constraints for closed chains or requirements on end-effector placement for articulated linkages. It is usually computationally too expensive to apply sampling-based planners to these problems since it is difficult to generate valid configurations. We overcome this challenge by redefining the robot\\'s degrees of freedom and constraints into a new set of parameters, called reachable distance space (RD-space), in which all configurations lie in the set of constraint-satisfying subspaces. This enables us to directly sample the constrained subspaces with complexity linear in the number of the robot\\'s degrees of freedom. In addition to supporting efficient sampling of configurations, we show that the RD-space formulation naturally supports planning and, in particular, we design a local planner suitable for use by sampling-based planners. We demonstrate the effectiveness and efficiency of our approach for several systems including closed chain planning with multiple loops, restricted end-effector sampling, and on-line planning for drawing/sculpting. We can sample single-loop closed chain systems with 1,000 links in time comparable to open chain sampling, and we can generate samples for 1,000-link multi-loop systems of varying topologies in less than a second. © 2010 The Author(s).

  5. An Approximate Optimal Relationship in the Sampling Plan with Inspection Errors

    Institute of Scientific and Technical Information of China (English)

    YANG Ji-ping; QIU Wan-hua; Martin NEWBY

    2001-01-01

    The paper presents and proves an approximate optimal relationship between sample size n andacceptance number c in the sampling plans under imperfect inspection which minimize the Bayesian risk. Theconclusion generalizes the result obtained by A. Hald on the assumption that the inspection is perfect.

  6. Enumerative and binomial sampling plans for citrus mealybug (Homoptera: pseudococcidae) in citrus groves.

    Science.gov (United States)

    Martínez-Ferrer, María Teresa; Ripollés, José Luís; Garcia-Marí, Ferran

    2006-06-01

    The spatial distribution of the citrus mealybug, Planococcus citri (Risso) (Homoptera: Pseudococcidae), was studied in citrus groves in northeastern Spain. Constant precision sampling plans were designed for all developmental stages of citrus mealybug under the fruit calyx, for late stages on fruit, and for females on trunks and main branches; more than 66, 286, and 101 data sets, respectively, were collected from nine commercial fields during 1992-1998. Dispersion parameters were determined using Taylor's power law, giving aggregated spatial patterns for citrus mealybug populations in three locations of the tree sampled. A significant relationship between the number of insects per organ and the percentage of occupied organs was established using either Wilson and Room's binomial model or Kono and Sugino's empirical formula. Constant precision (E = 0.25) sampling plans (i.e., enumerative plans) for estimating mean densities were developed using Green's equation and the two binomial models. For making management decisions, enumerative counts may be less labor-intensive than binomial sampling. Therefore, we recommend enumerative sampling plans for the use in an integrated pest management program in citrus. Required sample sizes for the range of population densities near current management thresholds, in the three plant locations calyx, fruit, and trunk were 50, 110-330, and 30, respectively. Binomial sampling, especially the empirical model, required a higher sample size to achieve equivalent levels of precision.

  7. Multimodal Logistics Network Design over Planning Horizon through a Hybrid Meta-Heuristic Approach

    Science.gov (United States)

    Shimizu, Yoshiaki; Yamazaki, Yoshihiro; Wada, Takeshi

    Logistics has been acknowledged increasingly as a key issue of supply chain management to improve business efficiency under global competition and diversified customer demands. This study aims at improving a quality of strategic decision making associated with dynamic natures in logistics network optimization. Especially, noticing an importance to concern with a multimodal logistics under multiterms, we have extended a previous approach termed hybrid tabu search (HybTS). The attempt intends to deploy a strategic planning more concretely so that the strategic plan can link to an operational decision making. The idea refers to a smart extension of the HybTS to solve a dynamic mixed integer programming problem. It is a two-level iterative method composed of a sophisticated tabu search for the location problem at the upper level and a graph algorithm for the route selection at the lower level. To keep efficiency while coping with the resulting extremely large-scale problem, we invented a systematic procedure to transform the original linear program at the lower-level into a minimum cost flow problem solvable by the graph algorithm. Through numerical experiments, we verified the proposed method outperformed the commercial software. The results indicate the proposed approach can make the conventional strategic decision much more practical and is promising for real world applications.

  8. Optimal planning of LEO active debris removal based on hybrid optimal control theory

    Science.gov (United States)

    Yu, Jing; Chen, Xiao-qian; Chen, Li-hu

    2015-06-01

    The mission planning of Low Earth Orbit (LEO) active debris removal problem is studied in this paper. Specifically, the Servicing Spacecraft (SSc) and several debris exist on near-circular near-coplanar LEOs. The SSc should repeatedly rendezvous with the debris, and de-orbit them until all debris are removed. Considering the long-duration effect of J2 perturbation, a linear dynamics model is used for each rendezvous. The purpose of this paper is to find the optimal service sequence and rendezvous path with minimum total rendezvous cost (Δv) for the whole mission, and some complex constraints (communication time window constraint, terminal state constraint, and time distribution constraint) should be satisfied meanwhile. Considering this mission as a hybrid optimal control problem, a mathematical model is proposed, as well as the solution method. The proposed approach is demonstrated by a typical active debris removal problem. Numerical experiments show that (1) the model and solution method proposed in this paper can effectively address the planning problem of LEO debris removal; (2) the communication time window constraint and the J2 perturbation have considerable influences on the optimization results; and (3) under the same configuration, some suboptimal sequences are equivalent to the optimal one since their difference in Δv cost is very small.

  9. ACCEPTANCE SAMPLING PLAN BASED ON TRUNCATED LIFE TESTS FOR COMPOUND RAYLEIGH DISTRIBUTION

    Directory of Open Access Journals (Sweden)

    Bhupendra Singh

    2013-12-01

    Full Text Available In this paper,a reliability sampling plan is developed assuming that lifetimes of the test units follow compound Rayleigh distribution and the life test is terminated at a pre-fixed time. This type of sampling plan is used to save the test time in practical situations. The minimum sample size required for ensuringthe specified mean life at specified consumer’s confidence level has been determined. The operating characteristic curve values of the sampling plans are examined with varying ratio of the true mean life to the specified life. The minimum such mean ratios are also obtained to minimize the producer’s risk at the specified level. For illustrative purpose, a numerical example has been discussed.

  10. Improved communication during treatment planning using light-curing hybrid wax for esthetic try-in restorations.

    Science.gov (United States)

    Witkowski, Siegbert; Kunz, Andreas; Wagenknecht, Günther

    2006-01-01

    The chance for a successful restorative outcome is improved when the clinician, the laboratory technician, and the patient agree on the design and appearance of the planned dental prosthesis as early as possible. A try-in of a planned dental restoration in the patient's mouth provides the parties involved in treatment planning with the ability to determine treatment goals together. The following article describes the use of a novel light-curing hybrid wax, a resin-like material that allows natural-looking, fracture-proof esthetic try-in restorations. Corrections can be made chairside by adding or removing material. The material is suitable for all indications involving fixed or removable dentures. Moreover, as the material can be burned without producing residues, it can be used directly in other applications such as pressable ceramics, ceramics pressed to metal, and casting techniques. A clinical case demonstrating the use of the hybrid wax is also presented.

  11. Statistical Sampling Plans for Prior Measurement Verification and Determination of the SNM Content of Inventories

    Energy Technology Data Exchange (ETDEWEB)

    G.F. Piepel, R.J. Brouns

    1982-03-01

    Current regulations require that prior information on the Special Nuclear Material (SNM) content o f a population o f containers be verified and that periodic measurements o f the SNM inventory of a facility be performed. This report develops and describes statistical sampling plans for accomplishing these tasks and compares results obtained by sampling to those obtained by the current practice o f performing a census (100% sampling)

  12. An Internationally Coordinated Science Management Plan for Samples Returned from Mars

    Science.gov (United States)

    Haltigin, T.; Smith, C. L.

    2015-12-01

    Mars Sample Return (MSR) remains a high priority of the planetary exploration community. Such an effort will undoubtedly be too large for any individual agency to conduct itself, and thus will require extensive global cooperation. To help prepare for an eventual MSR campaign, the International Mars Exploration Working Group (IMEWG) chartered the international Mars Architecture for the Return of Samples (iMARS) Phase II working group in 2014, consisting of representatives from 17 countries and agencies. The overarching task of the team was to provide recommendations for progressing towards campaign implementation, including a proposed science management plan. Building upon the iMARS Phase I (2008) outcomes, the Phase II team proposed the development of an International MSR Science Institute as part of the campaign governance, centering its deliberations around four themes: Organization: including an organizational structure for the Institute that outlines roles and responsibilities of key members and describes sample return facility requirements; Management: presenting issues surrounding scientific leadership, defining guidelines and assumptions for Institute membership, and proposing a possible funding model; Operations & Data: outlining a science implementation plan that details the preliminary sample examination flow, sample allocation process, and data policies; and Curation: introducing a sample curation plan that comprises sample tracking and routing procedures, sample sterilization considerations, and long-term archiving recommendations. This work presents a summary of the group's activities, findings, and recommendations, highlighting the role of international coordination in managing the returned samples.

  13. Economic Reliability Acceptance Sampling Plans from Truncated Life Tests based on the Burr Type XII Percentiles

    Directory of Open Access Journals (Sweden)

    Abdur Razzaque Mughal (Corresponding Author

    2011-09-01

    Full Text Available In this article, economic reliability acceptance sampling plan (ERASP is developed for the Burr type XII distribution when the life test is truncated at pre-specified designed parameters. The minimum termination time is necessary to ensure that the specified life percentile is found under a given producer’s risk. The operating characteristic values of the proposed plan are presented for various parameters. A comparative study of proposedplan and existing plan developed by Lio et al. (2010 is also discussed. The result is illustrated by a real dataset example.

  14. Planning Curvature-Constrained Paths to Multiple Goals Using Circle Sampling.

    Science.gov (United States)

    Lobaton, Edgar; Zhang, Jinghe; Patil, Sachin; Alterovitz, Ron

    2011-01-01

    We present a new sampling-based method for planning optimal, collision-free, curvature-constrained paths for nonholonomic robots to visit multiple goals in any order. Rather than sampling configurations as in standard sampling-based planners, we construct a roadmap by sampling circles of constant curvature and then generating feasible transitions between the sampled circles. We provide a closed-form formula for connecting the sampled circles in 2D and generalize the approach to 3D workspaces. We then formulate the multi-goal planning problem as finding a minimum directed Steiner tree over the roadmap. Since optimally solving the multi-goal planning problem requires exponential time, we propose greedy heuristics to efficiently compute a path that visits multiple goals. We apply the planner in the context of medical needle steering where the needle tip must reach multiple goals in soft tissue, a common requirement for clinical procedures such as biopsies, drug delivery, and brachytherapy cancer treatment. We demonstrate that our multi-goal planner significantly decreases tissue that must be cut when compared to sequential execution of single-goal plans.

  15. The Role of Vertex Consistency in Sampling-based Algorithms for Optimal Motion Planning

    CERN Document Server

    Arslan, Oktay

    2012-01-01

    Motion planning problems have been studied by both the robotics and the controls research communities for a long time, and many algorithms have been developed for their solution. Among them, incremental sampling-based motion planning algorithms, such as the Rapidly-exploring Random Trees (RRTs), and the Probabilistic Road Maps (PRMs) have become very popular recently, owing to their implementation simplicity and their advantages in handling high-dimensional problems. Although these algorithms work very well in practice, the quality of the computed solution is often not good, i.e., the solution can be far from the optimal one. A recent variation of RRT, namely the RRT* algorithm, bypasses this drawback of the traditional RRT algorithm, by ensuring asymptotic optimality as the number of samples tends to infinity. Nonetheless, the convergence rate to the optimal solution may still be slow. This paper presents a new incremental sampling-based motion planning algorithm based on Rapidly-exploring Random Graphs (RRG...

  16. Using Load Balancing to Scalably Parallelize Sampling-Based Motion Planning Algorithms

    KAUST Repository

    Fidel, Adam

    2014-05-01

    Motion planning, which is the problem of computing feasible paths in an environment for a movable object, has applications in many domains ranging from robotics, to intelligent CAD, to protein folding. The best methods for solving this PSPACE-hard problem are so-called sampling-based planners. Recent work introduced uniform spatial subdivision techniques for parallelizing sampling-based motion planning algorithms that scaled well. However, such methods are prone to load imbalance, as planning time depends on region characteristics and, for most problems, the heterogeneity of the sub problems increases as the number of processors increases. In this work, we introduce two techniques to address load imbalance in the parallelization of sampling-based motion planning algorithms: an adaptive work stealing approach and bulk-synchronous redistribution. We show that applying these techniques to representatives of the two major classes of parallel sampling-based motion planning algorithms, probabilistic roadmaps and rapidly-exploring random trees, results in a more scalable and load-balanced computation on more than 3,000 cores. © 2014 IEEE.

  17. Nuclear-Renewable Hybrid Energy Systems: 2016 Technology Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Bragg-Sitton, Shannon M. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boardman, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Suk Kim, Jong [Idaho National Lab. (INL), Idaho Falls, ID (United States); McKellar, Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States); Sabharwall, Piyush [Idaho National Lab. (INL), Idaho Falls, ID (United States); Chen, Jun [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cetiner, M. Sacit [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, T. Jay [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Qualls, A. Lou [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-03-01

    The United States is in the midst of an energy revolution, spurred by advancement of technology to produce unprecedented supplies of oil and natural gas. Simultaneously, there is an increasing concern for climate change attributed to greenhouse gas (GHG) emissions that, in large part, result from burning fossil fuels. An international consensus has concluded that the U.S. and other developed nations have an imperative to reduce GHG emissions to address these climate change concerns. The global desire to reduce GHG emissions has led to the development and deployment of clean energy resources and technologies, particularly renewable energy technologies, at a rapid rate. At the same time, each of the major energy sectors—the electric grid, industrial manufacturing, transportation, and the residential/commercial consumers— is increasingly becoming linked through information and communications technologies, advanced modeling and simulation, and controls. Coordination of clean energy generation technologies through integrated hybrid energy systems, as defined below, has the potential to further revolutionize energy services at the system level by coordinating the exchange of energy currency among the energy sectors in a manner that optimizes financial efficiency (including capital investments), maximizes thermodynamic efficiency (through best use of exergy, which is the potential to use the available energy in producing energy services), reduces environmental impacts when clean energy inputs are maximized, and provides resources for grid management. Rapid buildout of renewable technologies has been largely driven by local, state, and federal policies, such as renewable portfolio standards and production tax credits that incentivize investment in these generation sources. A foundational assumption within this program plan is that renewable technologies will continue to be major contributors to the future U.S. energy infrastructure. While increased use of clean

  18. Analysis of Tank 35H Samples in Support of Salt Batch Planning

    Energy Technology Data Exchange (ETDEWEB)

    Hay, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Coleman, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Diprete, D. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-04-30

    Savannah River Remediation obtained three samples from different heights within Tank 35H. The samples were analyzed by Savannah River National Laboratory to support Salt Batch planning. The results from the analysis indicate the compositions of the three samples show increasing concentrations for most analytes going from HTF-35-15-17 through HTF-35-15-19 corresponding to successively deeper sampling locations. The data indicate some stratification within the tank. The plutonium and Sr-90 concentrations measured in the filtered samples were slightly lower than in the decanted (unfiltered) samples. The difference in the results for the filtered and unfiltered samples likely lies within the expected uncertainty for the measurement, but may indicate that filtration removed a small amount of suspended material from the samples.

  19. [Sampling plan, weighting process and design effects of the Brazilian Oral Health Survey].

    Science.gov (United States)

    Silva, Nilza Nunes da; Roncalli, Angelo Giuseppe

    2013-12-01

    To present aspects of the sampling plan of the Brazilian Oral Health Survey (SBBrasil Project). with theoretical and operational issues that should be taken into account in the primary data analyses. The studied population was composed of five demographic groups from urban areas of Brazil in 2010. Two and three stage cluster sampling was used. adopting different primary units. Sample weighting and design effects (deff) were used to evaluate sample consistency. In total. 37,519 individuals were reached. Although the majority of deff estimates were acceptable. some domains showed distortions. The majority (90%) of the samples showed results in concordance with the precision proposed in the sampling plan. The measures to prevent losses and the effects the cluster sampling process in the minimum sample sizes proved to be effective for the deff. which did not exceeded 2. even for results derived from weighting. The samples achieved in the SBBrasil 2010 survey were close to the main proposals for accuracy of the design. Some probabilities proved to be unequal among the primary units of the same domain. Users of this database should bear this in mind, introducing sample weighting in calculations of point estimates, standard errors, confidence intervals and design effects.

  20. Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminoma

    NARCIS (Netherlands)

    Looijenga, LHJ; Rosenberg, C; van Gurp, RJHLM; Geelen, E; van Echten-Arends, J; de Jong, B; Mostert, M

    2000-01-01

    Human testicular germ cell tumours (TGCTs) of adolescents and adults, both seminomas and non-seminomas, originate from intratubular germ cell neoplasia (IGCN). Comparative genomic hybridization (CGH) was applied to microdissected samples from different stages of the development of a seminoma and a m

  1. Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminoma

    NARCIS (Netherlands)

    Looijenga, LHJ; Rosenberg, C; van Gurp, RJHLM; Geelen, E; van Echten-Arends, J; de Jong, B; Mostert, M

    Human testicular germ cell tumours (TGCTs) of adolescents and adults, both seminomas and non-seminomas, originate from intratubular germ cell neoplasia (IGCN). Comparative genomic hybridization (CGH) was applied to microdissected samples from different stages of the development of a seminoma and a

  2. Hybrid Capture 2 and cobas human papillomavirus assays perform similarly on SurePath samples from women with abnormalities

    DEFF Research Database (Denmark)

    Fornari, D; Rebolj, M; Bjerregaard, B

    2016-01-01

    OBJECTIVE: In two laboratories (Departments of Pathology, Copenhagen University Hospitals of Herlev and Hvidovre), we compared cobas and Hybrid Capture 2 (HC2) human papillomavirus (HPV) assays using SurePath® samples from women with atypical squamous cells of undetermined significance (ASCUS) at...

  3. A hybrid design-based and model-based sampling approach to estimate the temporal trend of spatial means

    NARCIS (Netherlands)

    Brus, D.J.; Gruijter, de J.J.

    2012-01-01

    This paper launches a hybrid sampling approach, entailing a design-based approach in space followed by a model-based approach in time, for estimating temporal trends of spatial means or totals. The underlying space–time process that generated the soil data is only partly described, viz. by a linear

  4. Swarm satellite mission scheduling & planning using Hybrid Dynamic Mutation Genetic Algorithm

    Science.gov (United States)

    Zheng, Zixuan; Guo, Jian; Gill, Eberhard

    2017-08-01

    Space missions have traditionally been controlled by operators from a mission control center. Given the increasing number of satellites for some space missions, generating a command list for multiple satellites can be time-consuming and inefficient. Developing multi-satellite, onboard mission scheduling & planning techniques is, therefore, a key research field for future space mission operations. In this paper, an improved Genetic Algorithm (GA) using a new mutation strategy is proposed as a mission scheduling algorithm. This new mutation strategy, called Hybrid Dynamic Mutation (HDM), combines the advantages of both dynamic mutation strategy and adaptive mutation strategy, overcoming weaknesses such as early convergence and long computing time, which helps standard GA to be more efficient and accurate in dealing with complex missions. HDM-GA shows excellent performance in solving both unconstrained and constrained test functions. The experiments of using HDM-GA to simulate a multi-satellite, mission scheduling problem demonstrates that both the computation time and success rate mission requirements can be met. The results of a comparative test between HDM-GA and three other mutation strategies also show that HDM has outstanding performance in terms of speed and reliability.

  5. Hybrid SWOT Approach for Strategic Planning and Formulation in China Worldwide Express Mail Service

    Directory of Open Access Journals (Sweden)

    X.P. Wang

    2014-04-01

    Full Text Available The traditional SWOT tool, which lists the S, W, O, T factors and groups them together to form some strategies, is convenient for analyzing but not effective enough for strategic formulation. This paper proposes a hybrid “three-stage” qualitative and quantitative SWOT model, trying to narrow the gap between strategic analysis and strategic formulation by first confirming the SWOT factors, second narrowing the selection area and last making optimal strategies. First, the SWOT-AHP model is used to analyze and evaluate the external and internal environment factors. Then we narrow the analysis field down to two levels by using strategic quadrilateral model, where the quadrant of the gravity centre is used to represent the market position. Finally correlation rules, including matrix calculations, maximum and sub-maximum sub-array techniques, are introduced to formulate the effective strategies, which focus on the most influential factors. A case study of EMS is conducted with the objective of validating the effectiveness in strategic planning and management.

  6. All-atom/coarse-grained hybrid predictions of distribution coefficients in SAMPL5

    Science.gov (United States)

    Genheden, Samuel; Essex, Jonathan W.

    2016-11-01

    We present blind predictions submitted to the SAMPL5 challenge on calculating distribution coefficients. The predictions were based on estimating the solvation free energies in water and cyclohexane of the 53 compounds in the challenge. These free energies were computed using alchemical free energy simulations based on a hybrid all-atom/coarse-grained model. The compounds were treated with the general Amber force field, whereas the solvent molecules were treated with the Elba coarse-grained model. Considering the simplicity of the solvent model and that we approximate the distribution coefficient with the partition coefficient of the neutral species, the predictions are of good accuracy. The correlation coefficient, R is 0.64, 82 % of the predictions have the correct sign and the mean absolute deviation is 1.8 log units. This is on a par with or better than the other simulation-based predictions in the challenge. We present an analysis of the deviations to experiments and compare the predictions to another submission that used all-atom solvent.

  7. New hybrid materials as Zn(II) sorbents in water samples

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Quintanilla, Damian, E-mail: damian.perez@urjc.es [Departamento de Quimica Inorganica y Analitica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipan s/n, 28933 Mostoles, Madrid (Spain); Sanchez, Alfredo; Hierro, Isabel del; Fajardo, Mariano [Departamento de Quimica Inorganica y Analitica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipan s/n, 28933 Mostoles, Madrid (Spain); Sierra, Isabel, E-mail: isabel.sierra@urjc.es [Departamento de Quimica Inorganica y Analitica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipan s/n, 28933 Mostoles, Madrid (Spain)

    2010-09-15

    Mesoporous silicas have been chemically modified with 5-mercapto-1-methyltetrazole (MTTZ) obtaining hybrid materials denominated MTTZ-MSU-2 and MTTZ-HMS. These materials were employed as Zn(II) sorbents from aqueous media at room temperature. The effect of several variables (stirring time, pH, presence of other metals) has been studied using batch and column techniques. Flame atomic absorption spectrometry (FAAS) was used to determinate Zn(II) concentration in the filtrate or in the eluted solution after the adsorption process. The results indicate that under pH 8, the maximum adsorption value was 0.94 {+-} 0.01 and 0.72 {+-} 0.01 mmol Zn(II)/g for MTTZ-MSU-2 and MTTZ-HMS, respectively. In tap water samples, a preconcentration factor of 200 was obtained. On the basis of these results, it can be concluded that it is possible to modify chemically MSU-2 and HMS with 5-mercapto-1-methyltetrazole and to use the resulting modified mesoporous silica as an effective adsorbent for Zn(II) in aqueous media.

  8. Analysis of tank 23H samples in support of salt batch planning

    Energy Technology Data Exchange (ETDEWEB)

    Hay, M. S. [Savannah River Site (SRS), Aiken, SC (United States); Coleman, C. J. [Savannah River Site (SRS), Aiken, SC (United States); Diprete, D. P. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-08-14

    Savannah River Remediation obtained three samples from different heights within Tank 23H. The samples were analyzed by Savannah River National Laboratory to support salt batch planning. The results from the analysis indicate the top two samples from the tank appear similar in composition. The lowest sample from the tank contained significantly more solids and a more concentrated salt solution. The filtered supernate from the bottom sample showed ~60% lower Sr-90 and Pu-238 concentrations than the decanted (unfiltered) supernate results which may indicate the presence of some small amount of entrained solid particles in the decanted sample. The mercury concentrations measured in the filtered supernate were fairly low for all three samples ranging from 11.2 to 42.3 mg/L.

  9. Scheduling Algorithm for Mission Planning and Logistics Evaluation (SAMPLE). Volume 2: Mission payloads subsystem description

    Science.gov (United States)

    Dupnick, E.; Wiggins, D.

    1980-01-01

    The scheduling algorithm for mission planning and logistics evaluation (SAMPLE) is presented. Two major subsystems are included: The mission payloads program; and the set covering program. Formats and parameter definitions for the payload data set (payload model), feasible combination file, and traffic model are documented.

  10. Food safety assurance systems: Microbiological testing, sampling plans, and microbiological criteria

    NARCIS (Netherlands)

    Zwietering, M.H.; Ross, T.; Gorris, L.G.M.

    2014-01-01

    Microbiological criteria give information about the quality or safety of foods. A key component of a microbiological criterion is the sampling plan. Considering: (1) the generally low level of pathogens that are deemed tolerable in foods, (2) large batch sizes, and (3) potentially substantial hetero

  11. Food safety assurance systems: Microbiological testing, sampling plans, and microbiological criteria

    NARCIS (Netherlands)

    Zwietering, M.H.; Ross, T.; Gorris, L.G.M.

    2014-01-01

    Microbiological criteria give information about the quality or safety of foods. A key component of a microbiological criterion is the sampling plan. Considering: (1) the generally low level of pathogens that are deemed tolerable in foods, (2) large batch sizes, and (3) potentially substantial

  12. Sample size planning for the coefficient of variation from the accuracy in parameter estimation approach.

    Science.gov (United States)

    Kelley, Ken

    2007-11-01

    The accuracy in parameter estimation approach to sample size planning is developed for the coefficient of variation, where the goal of the method is to obtain an accurate parameter estimate by achieving a sufficiently narrow confidence interval. The first method allows researchers to plan sample size so that the expected width of the confidence interval for the population coefficient of variation is sufficiently narrow. A modification allows a desired degree of assurance to be incorporated into the method, so that the obtained confidence interval will be sufficiently narrow with some specified probability (e.g., 85% assurance that the 95 confidence interval width will be no wider than to units). Tables of necessary sample size are provided for a variety of scenarios that may help researchers planning a study where the coefficient of variation is of interest plan an appropriate sample size in order to have a sufficiently narrow confidence interval, optionally with somespecified assurance of the confidence interval being sufficiently narrow. Freely available computer routines have been developed that allow researchers to easily implement all of the methods discussed in the article.

  13. Practical sampling plans for Varroa destructor (Acari: Varroidae) in Apis mellifera (Hymenoptera: Apidae) colonies and apiaries.

    Science.gov (United States)

    Lee, K V; Moon, R D; Burkness, E C; Hutchison, W D; Spivak, M

    2010-08-01

    The parasitic mite Varroa destructor Anderson & Trueman (Acari: Varroidae) is arguably the most detrimental pest of the European-derived honey bee, Apis mellifera L. Unfortunately, beekeepers lack a standardized sampling plan to make informed treatment decisions. Based on data from 31 commercial apiaries, we developed sampling plans for use by beekeepers and researchers to estimate the density of mites in individual colonies or whole apiaries. Beekeepers can estimate a colony's mite density with chosen level of precision by dislodging mites from approximately to 300 adult bees taken from one brood box frame in the colony, and they can extrapolate to mite density on a colony's adults and pupae combined by doubling the number of mites on adults. For sampling whole apiaries, beekeepers can repeat the process in each of n = 8 colonies, regardless of apiary size. Researchers desiring greater precision can estimate mite density in an individual colony by examining three, 300-bee sample units. Extrapolation to density on adults and pupae may require independent estimates of numbers of adults, of pupae, and of their respective mite densities. Researchers can estimate apiary-level mite density by taking one 300-bee sample unit per colony, but should do so from a variable number of colonies, depending on apiary size. These practical sampling plans will allow beekeepers and researchers to quantify mite infestation levels and enhance understanding and management of V. destructor.

  14. Sample-Size Planning for More Accurate Statistical Power: A Method Adjusting Sample Effect Sizes for Publication Bias and Uncertainty.

    Science.gov (United States)

    Anderson, Samantha F; Kelley, Ken; Maxwell, Scott E

    2017-09-01

    The sample size necessary to obtain a desired level of statistical power depends in part on the population value of the effect size, which is, by definition, unknown. A common approach to sample-size planning uses the sample effect size from a prior study as an estimate of the population value of the effect to be detected in the future study. Although this strategy is intuitively appealing, effect-size estimates, taken at face value, are typically not accurate estimates of the population effect size because of publication bias and uncertainty. We show that the use of this approach often results in underpowered studies, sometimes to an alarming degree. We present an alternative approach that adjusts sample effect sizes for bias and uncertainty, and we demonstrate its effectiveness for several experimental designs. Furthermore, we discuss an open-source R package, BUCSS, and user-friendly Web applications that we have made available to researchers so that they can easily implement our suggested methods.

  15. Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    TEMPLETON, A.M.

    2000-04-10

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification. Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissions Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.

  16. Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    TEMPLETON, A.M.

    2000-03-06

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification. Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissions Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.

  17. Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    TEMPLETON, A.M.

    2000-01-31

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissions Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.

  18. Tank 241-SY-101 push mode core sampling and analysis plan

    Energy Technology Data Exchange (ETDEWEB)

    CONNER, J.M.

    1998-10-09

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-SY-101 (SY-101). It is written in accordance with Data Quality Objective to Support Resolution of the Flammable Gas Safety Issue (Bauer 1998), Low Activity Waste Feed Data Quality Objectives (Wiemers and Miller 1997 and DOE 1998), Data Quality Objectives for TWRS Privatization Phase I: Confirm Tank T is an Appropriate Feed Source for Low-Activity Waste Feed Batch X (Certa 1998), and the Tank Safety Screening Data Quality Objective (Dukelow et al. 1995). The Tank Characterization Technical Sampling Basis document (Brown et al. 1998) indicates that these issues apply to tank SY-101 for this sampling event. Brown et al. also identifies high-level waste, regulatory, pretreatment and disposal issues as applicable issues for this tank. However, these issues will not be addressed via this sampling event.

  19. Increasing the sampling efficiency of protein conformational transition using velocity-scaling optimized hybrid explicit/implicit solvent REMD simulation

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Yuqi; Wang, Jinan; Shao, Qiang, E-mail: qshao@mail.shcnc.ac.cn, E-mail: Jiye.Shi@ucb.com, E-mail: wlzhu@mail.shcnc.ac.cn; Zhu, Weiliang, E-mail: qshao@mail.shcnc.ac.cn, E-mail: Jiye.Shi@ucb.com, E-mail: wlzhu@mail.shcnc.ac.cn [ACS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203 (China); Shi, Jiye, E-mail: qshao@mail.shcnc.ac.cn, E-mail: Jiye.Shi@ucb.com, E-mail: wlzhu@mail.shcnc.ac.cn [UCB Pharma, 216 Bath Road, Slough SL1 4EN (United Kingdom)

    2015-03-28

    The application of temperature replica exchange molecular dynamics (REMD) simulation on protein motion is limited by its huge requirement of computational resource, particularly when explicit solvent model is implemented. In the previous study, we developed a velocity-scaling optimized hybrid explicit/implicit solvent REMD method with the hope to reduce the temperature (replica) number on the premise of maintaining high sampling efficiency. In this study, we utilized this method to characterize and energetically identify the conformational transition pathway of a protein model, the N-terminal domain of calmodulin. In comparison to the standard explicit solvent REMD simulation, the hybrid REMD is much less computationally expensive but, meanwhile, gives accurate evaluation of the structural and thermodynamic properties of the conformational transition which are in well agreement with the standard REMD simulation. Therefore, the hybrid REMD could highly increase the computational efficiency and thus expand the application of REMD simulation to larger-size protein systems.

  20. Calculation of the radionuclides in PWR spent fuel samples for SFR experiment planning.

    Energy Technology Data Exchange (ETDEWEB)

    Naegeli, Robert Earl

    2004-06-01

    This report documents the calculation of radionuclide content in the pressurized water reactor (PWR) spent fuel samples planned for use in the Spent Fuel Ratio (SPR) Experiments at Sandia National Laboratories, Albuquerque, New Mexico (SNL) to aid in experiment planning. The calculation methods using the ORIGEN2 and ORIGEN-ARP computer codes and the input modeling of the planned PWR spent fuel from the H. B. Robinson and the Surry nuclear power plants are discussed. The safety hazards for the calculated nuclide inventories in the spent fuel samples are characterized by the potential airborne dose and by the portion of the nuclear facility hazard category 2 and 3 thresholds that the experiment samples would present. In addition, the gamma ray photon energy source for the nuclide inventories is tabulated to facilitate subsequent calculation of the direct and shielded dose rates expected from the samples. The relative hazards of the high burnup 72 gigawatt-day per metric ton of uranium (GWd/MTU) spent fuel from H. B. Robinson and the medium burnup 36 GWd/MTU spent fuel from Surry are compared against a parametric calculation of various fuel burnups to assess the potential for higher hazard PWR fuel samples.

  1. UMTRA project water sampling and analysis plan, Falls City, Texas. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Planned, routine ground water sampling activities at the US Department of Energy (DOE) Uranium Mill Tailings Remedial Action (UMTRA) Project site near Falls City, Texas, are described in this water sampling and analysis plan (WSAP). The following plan identifies and justifies the sampling locations, analytical parameters, and sampling frequency for the routine monitoring stations at the site. The ground water data are used for site characterization and risk assessment. The regulatory basis for routine ground water monitoring at UMTRA Project sites is derived from the US Environmental Protection Agency (EPA) regulations in 40 CFR Part 192. Sampling procedures are guided by the UMTRA Project standard operating procedures (SOP) (JEG, n.d.), the Technical Approach Document (TAD) (DOE, 1989), and the most effective technical approach for the site. The Falls City site is in Karnes County, Texas, approximately 8 miles [13 kilometers southwest of the town of Falls City and 46 mi (74 km) southeast of San Antonio, Texas. Before surface remedial action, the tailings site consisted of two parcels. Parcel A consisted of the mill site, one mill building, five tailings piles, and one tailings pond south of Farm-to-Market (FM) Road 1344 and west of FM 791. A sixth tailings pile designated Parcel B was north of FM 791 and east of FM 1344.

  2. Double Shell Tank (DST) Ventilation System Vapor Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    SASAKI, L.M.

    2000-06-08

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples from the primary ventilation systems of the AN, AP, AW, and AY/AZ tank farms. Sampling will be performed in accordance with Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissions Sampling and Analysis (Air DQO) (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications. Vapor samples will be obtained from tank farm ventilation systems, downstream from the tanks and upstream of any filtration. Samples taken in support of the DQO will consist of SUMMA{trademark} canisters, triple sorbent traps (TSTs), sorbent tube trains (STTs), polyurethane foam (PUF) samples. Particulate filter samples and tritium traps will be taken for radiation screening to allow the release of the samples for analysis. The following sections provide the general methodology and procedures to be used in the preparation, retrieval, transport, analysis, and reporting of results from the vapor samples.

  3. A hybrid DNA extraction method for the qualitative and quantitative assessment of bacterial communities from poultry production samples.

    Science.gov (United States)

    Rothrock, Michael J; Hiett, Kelli L; Gamble, John; Caudill, Andrew C; Cicconi-Hogan, Kellie M; Caporaso, J Gregory

    2014-12-10

    The efficacy of DNA extraction protocols can be highly dependent upon both the type of sample being investigated and the types of downstream analyses performed. Considering that the use of new bacterial community analysis techniques (e.g., microbiomics, metagenomics) is becoming more prevalent in the agricultural and environmental sciences and many environmental samples within these disciplines can be physiochemically and microbiologically unique (e.g., fecal and litter/bedding samples from the poultry production spectrum), appropriate and effective DNA extraction methods need to be carefully chosen. Therefore, a novel semi-automated hybrid DNA extraction method was developed specifically for use with environmental poultry production samples. This method is a combination of the two major types of DNA extraction: mechanical and enzymatic. A two-step intense mechanical homogenization step (using bead-beating specifically formulated for environmental samples) was added to the beginning of the "gold standard" enzymatic DNA extraction method for fecal samples to enhance the removal of bacteria and DNA from the sample matrix and improve the recovery of Gram-positive bacterial community members. Once the enzymatic extraction portion of the hybrid method was initiated, the remaining purification process was automated using a robotic workstation to increase sample throughput and decrease sample processing error. In comparison to the strict mechanical and enzymatic DNA extraction methods, this novel hybrid method provided the best overall combined performance when considering quantitative (using 16S rRNA qPCR) and qualitative (using microbiomics) estimates of the total bacterial communities when processing poultry feces and litter samples.

  4. A risk-based sampling plan for monitoring of histamine in fish products.

    Science.gov (United States)

    Guillier, L; Thébault, A; Gauchard, F; Pommepuy, M; Guignard, A; Malle, P

    2011-02-01

    In 2008, the French Institute for Public Health Surveillance reported an increase in the number of histamine food poisoning outbreaks and cases in France. The aim of this study was to propose a new monitoring plan for characterizing consumers' exposure to histamine through fishery products. As fish products of concern are numerous, we proposed that the number of samples allocated for a fish category be chosen based on the risk associated with the category. Point risk estimates of histamine poisoning were assessed with the Risk Ranger tool. Fresh fish with high histidine content was found to contribute most to the number of cases. The (estimated) risks associated with the consumption of canned and deep-frozen fish appear marginal as compared with the risk associated with fresh fish with high histidine concentrations. Accordingly, we recommend excluding canned and deep-frozen fish from the monitoring plan, although these risk estimates can be biased. Within a category, samples were proportional to the relative food consumption of the different fishes. The spatial and seasonal consumption patterns were also taken into account for the design of the new monitoring plan. By testing appropriate numbers of samples from categories of fish products of concern, this plan will permit investigation of trends or comparison of product categories presenting risks of histamine poisoning.

  5. Mobilization Protocols for Hybrid Sensors for Environmental AOP Sampling (HySEAS) Observations

    Science.gov (United States)

    Hooker, Stanford B.

    2014-01-01

    The protocols presented here enable the proper mobilization of the latest-generation instruments for measuring the apparent optical properties (AOPs) of aquatic ecosystems. The protocols are designed for the Hybrid Sensors for Environmental AOP Sampling (HySEAS) class of instruments, but are applicable to the community of practice for AOP measurements. The protocols are organized into eleven sections beyond an introductory overview: a) cables and connectors, b) HySEAS instruments, c) platform preparation, d) instrument installation, e) cable installation, f) test deployment, g) test recovery, h) maintenance, i) shipping, j) storage, and k) smallboat operations. Each section concentrates on documenting how to prevent the most likely faults, remedy them should they occur, and accomplishing both with the proper application of a modest set of useful tools. Within the twelve sections, there are Socratic exercises to stimulate thought, and the answers to these exercises appear in Appendix A. Frequently asked questions (FAQs) are summarized in a separate section after the answers to the exercises in Appendix B. For practitioners unfamiliar with the nautical terms used throughout this document plus others likely encountered at sea, an abbreviated dictionary of nautical terms appears in Appendix C. An abbreviated dictionary of radiotelephone terms is presented in Appendix D. To ensure familiarity with many of the tools that are presented, Appendix E provides a description of the tools alongside a thumbnail picture. Abbreviated deployment checklists and cable diagrams are provided in Appendix F. The document concludes with an acknowledgments section, a glossary of acronyms, a definition of symbols, and a list of references.

  6. A sampling plan for riparian birds of the Lower Colorado River-Final Report

    Science.gov (United States)

    Bart, Jonathan; Dunn, Leah; Leist, Amy

    2010-01-01

    A sampling plan was designed for the Bureau of Reclamation for selected riparian birds occurring along the Colorado River from Lake Mead to the southerly International Boundary with Mexico. The goals of the sampling plan were to estimate long-term trends in abundance and investigate habitat relationships especially in new habitat being created by the Bureau of Reclamation. The initial objective was to design a plan for the Gila Woodpecker (Melanerpes uropygialis), Arizona Bell's Vireo (Vireo bellii arizonae), Sonoran Yellow Warbler (Dendroica petechia sonorana), Summer Tanager (Piranga rubra), Gilded Flicker (Colaptes chrysoides), and Vermilion Flycatcher (Pyrocephalus rubinus); however, too little data were obtained for the last two species. Recommendations were therefore based on results for the first four species. The study area was partitioned into plots of 7 to 23 hectares. Plot borders were drawn to place the best habitat for the focal species in the smallest number of plots so that survey efforts could be concentrated on these habitats. Double sampling was used in the survey. In this design, a large sample of plots is surveyed a single time, yielding estimates of unknown accuracy, and a subsample is surveyed intensively to obtain accurate estimates. The subsample is used to estimate detection ratios, which are then applied to the results from the extensive survey to obtain unbiased estimates of density and population size. These estimates are then used to estimate long-term trends in abundance. Four sampling plans for selecting plots were evaluated based on a simulation using data from the Breeding Bird Survey. The design with the highest power involved selecting new plots every year. Power with 80 plots surveyed per year was more than 80 percent for three of the four species. Results from the surveys were used to provide recommendations to the Bureau of Reclamation for their surveys of new habitat being created in the study area.

  7. AN ECONOMIC RELIABILITY EFFICIENT GROUP ACCEPTANCE SAMPLING PLANS FOR FAMILY PARETO DISTRIBUTIONS

    Directory of Open Access Journals (Sweden)

    Muhammad Ismail

    2013-12-01

    Full Text Available The present research article deals with an economic reliability efficient group acceptance sampling plan for time truncated tests which are based on the total number of failures assuming that the life time of a product follows the family for Pareto distribution. This research is proposed when a multiple number of products as a group can be observed simultaneously in a tester. The minimum termination time required for a given group size and acceptance number is determined such that the producer and consumer risks are satisfied for specific standard of quality level, while the number of groups and the number of testers are pre-assumed. Comparison studies are made between the proposed plan and the existing plan on the basis of minimum termination time. Two real examples are also discussed.

  8. Visual Sample Plan Version 1.0 User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, James R.; Hassig, Nancy L.; Wilson, John E.; Gilbert, Richard O.

    2001-04-13

    This user's guide describes Visual Sample Plan (VSP) Version 1.0 and provides instructions for using the software. VSP selects the appropriate number and location of environmental samples to ensure that the results of statistical tests performed to provide input to environmental decisions have the required confidence and performance. VSP Version 1.0 provides sample-size equations or algorithms needed by specific statistical tests appropriate for specific environmental sampling objectives. The easy-to-use program is highly visual and graphic. VSP runs on personal computers with Microsoft Windows operating systems (95, 98, Millenium Edition, 2000, and Windows NT). Designed primarily for project managers and users without expertise in statistics, VSP is applicable to any two-dimensional geographical population to be sampled (e.g., surface soil, a defined layer of subsurface soil, building surfaces, water bodies, and other similar applications) for studies of environmental quality.

  9. A Rapid Sampling Plan for Scirtothrips dorsalis (Thysanoptera: Thripidae) on Container Shrub Rose (Rosa 'Radrazz').

    Science.gov (United States)

    Aristizábal, Luis F; Moura Mascarin, Gabriel; Cherry, Ron; Chaves-Cordoba, Bernardo; Arthurs, Steven P

    2016-12-01

    The development of simple and reliable pest sampling programs is needed for growers to adopt economic or aesthetic injury levels. We developed a sampling plan for monitoring chilli thrips Scirtothrips dorsalis Hood populations on KnockOut shrub roses under simulated nursery conditions. The distribution of S. dorsalis among different plant structures revealed that most adults and larvae are found on foliar terminals, when compared with buds and flowers. Based on thrips distribution, the third leaf of actively growing terminals was used to determine a sequential sampling model. Thrips had an aggregated distribution, based on Taylor's power law and Iwao's mean crowding index, with both models showing a good fit (i.e., R2 of ∼0.8 and ∼0.9, respectively). Based on these model parameters, the number of samples required to estimate populations with a 10% precision was ∼30 leaves according to Green's and Kuno's enumerative sequential sampling plans. A binomial model also estimated the proportion of infested leaf terminals as a function of insect density with an R2 value of 0.85. An additional study demonstrated that correlation between visual damage to the third leaf terminal and initial thrips populations was modeled by simple power functions. This finding suggests that a more rapid visual sampling of plant damage can be used to indirectly estimate S. dorsalis populations. Our sampling plan provides a tool to monitor S. dorsalis populations that could be used to help make management decisions for this pest in commercial nurseries. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. Planning Considerations for a Mars Sample Receiving Facility: Summary and Interpretation of Three Design Studies

    Science.gov (United States)

    Beaty, David W.; Allen, Carlton C.; Bass, Deborah S.; Buxbaum, Karen L.; Campbell, James K.; Lindstrom, David J.; Miller, Sylvia L.; Papanastassiou, Dimitri A.

    2009-10-01

    It has been widely understood for many years that an essential component of a Mars Sample Return mission is a Sample Receiving Facility (SRF). The purpose of such a facility would be to take delivery of the flight hardware that lands on Earth, open the spacecraft and extract the sample container and samples, and conduct an agreed-upon test protocol, while ensuring strict containment and contamination control of the samples while in the SRF. Any samples that are found to be non-hazardous (or are rendered non-hazardous by sterilization) would then be transferred to long-term curation. Although the general concept of an SRF is relatively straightforward, there has been considerable discussion about implementation planning. The Mars Exploration Program carried out an analysis of the attributes of an SRF to establish its scope, including minimum size and functionality, budgetary requirements (capital cost, operating costs, cost profile), and development schedule. The approach was to arrange for three independent design studies, each led by an architectural design firm, and compare the results. While there were many design elements in common identified by each study team, there were significant differences in the way human operators were to interact with the systems. In aggregate, the design studies provided insight into the attributes of a future SRF and the complex factors to consider for future programmatic planning.

  11. Sampling and analysis plan for assessment of beryllium in soils surrounding TA-40 building 15

    Energy Technology Data Exchange (ETDEWEB)

    Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-12-19

    Technical Area (TA) 40 Building 15 (40-15) is an active firing site at Los Alamos National Laboratory. The weapons facility operations (WFO) group plans to build an enclosure over the site in 2017, so that test shots may be conducted year-round. The enclosure project is described in PRID 16P-0209. 40-15 is listed on LANL OSH-ISH’s beryllium inventory, which reflects the potential for beryllium in/on soils and building surfaces at 40-15. Some areas in and around 40-15 have previously been sampled for beryllium, but past sampling efforts did not achieve complete spatial coverage of the area. This Sampling and Analysis Plan (SAP) investigates the area surrounding 40-15 via 9 deep (≥1-ft.) soil samples and 11 shallow (6-in.) soil samples. These samples will fill the spatial data gaps for beryllium at 40-15, and will be used to support OSH-ISH’s final determination of 40-15’s beryllium registry status. This SAP has been prepared by the Environmental Health Physics program in consultation with the Industrial Hygiene program. Industrial Hygiene is the owner of LANL’s beryllium program, and will make a final determination with regard to the regulatory status of beryllium at 40-15.

  12. Planning considerations for a Mars Sample Receiving Facility: summary and interpretation of three design studies.

    Science.gov (United States)

    Beaty, David W; Allen, Carlton C; Bass, Deborah S; Buxbaum, Karen L; Campbell, James K; Lindstrom, David J; Miller, Sylvia L; Papanastassiou, Dimitri A

    2009-10-01

    It has been widely understood for many years that an essential component of a Mars Sample Return mission is a Sample Receiving Facility (SRF). The purpose of such a facility would be to take delivery of the flight hardware that lands on Earth, open the spacecraft and extract the sample container and samples, and conduct an agreed-upon test protocol, while ensuring strict containment and contamination control of the samples while in the SRF. Any samples that are found to be non-hazardous (or are rendered non-hazardous by sterilization) would then be transferred to long-term curation. Although the general concept of an SRF is relatively straightforward, there has been considerable discussion about implementation planning. The Mars Exploration Program carried out an analysis of the attributes of an SRF to establish its scope, including minimum size and functionality, budgetary requirements (capital cost, operating costs, cost profile), and development schedule. The approach was to arrange for three independent design studies, each led by an architectural design firm, and compare the results. While there were many design elements in common identified by each study team, there were significant differences in the way human operators were to interact with the systems. In aggregate, the design studies provided insight into the attributes of a future SRF and the complex factors to consider for future programmatic planning.

  13. Visual Sample Plan Version 7.0 User's Guide

    Energy Technology Data Exchange (ETDEWEB)

    Matzke, Brett D.; Newburn, Lisa LN; Hathaway, John E.; Bramer, Lisa M.; Wilson, John E.; Dowson, Scott T.; Sego, Landon H.; Pulsipher, Brent A.

    2014-03-01

    User's guide for VSP 7.0 This user's guide describes Visual Sample Plan (VSP) Version 7.0 and provides instructions for using the software. VSP selects the appropriate number and location of environmental samples to ensure that the results of statistical tests performed to provide input to risk decisions have the required confidence and performance. VSP Version 7.0 provides sample-size equations or algorithms needed by specific statistical tests appropriate for specific environmental sampling objectives. It also provides data quality assessment and statistical analysis functions to support evaluation of the data and determine whether the data support decisions regarding sites suspected of contamination. The easy-to-use program is highly visual and graphic. VSP runs on personal computers with Microsoft Windows operating systems (XP, Vista, Windows 7, and Windows 8). Designed primarily for project managers and users without expertise in statistics, VSP is applicable to two- and three-dimensional populations to be sampled (e.g., rooms and buildings, surface soil, a defined layer of subsurface soil, water bodies, and other similar applications) for studies of environmental quality. VSP is also applicable for designing sampling plans for assessing chem/rad/bio threat and hazard identification within rooms and buildings, and for designing geophysical surveys for unexploded ordnance (UXO) identification.

  14. Presentation of the intrasubject coefficient of variation for sample size planning in bioequivalence studies.

    Science.gov (United States)

    Hauschke, D; Steinijans, W V; Diletti, E; Schall, R; Luus, H G; Elze, M; Blume, H

    1994-07-01

    Bioequivalence studies are generally performed as crossover studies and, therefore, information on the intrasubject coefficient of variation is needed for sample size planning. Unfortunately, this information is usually not presented in publications on bioequivalence studies, and only the pooled inter- and intrasubject coefficient of variation for either test or reference formulation is reported. Thus, the essential information for sample size planning of future studies is not made available to other researchers. In order to overcome such shortcomings, the presentation of results from bioequivalence studies should routinely include the intrasubject coefficient of variation. For the relevant coefficients of variation, theoretical background together with modes of calculation and presentation are given in this communication with particular emphasis on the multiplicative model.

  15. Hybrid modelling for ATES planning and operation in the Utrecht city centre

    Science.gov (United States)

    Jaxa-Rozen, Marc; Bloemendal, Martin; Kwakkel, Jan; Rostampour, Vahab

    2016-04-01

    Aquifer Thermal Energy Storage (ATES) systems can significantly reduce the energy use and greenhouse gas emissions of buildings in temperate climates. However, the rapid adoption of these systems has evidenced a number of emergent issues with the operation and management of urban ATES systems, which require careful spatial planning to avoid thermal interferences or conflicts with other subsurface functions. These issues have become particularly relevant in the Netherlands, which are currently the leading market for ATES (Bloemendal et al., 2015). In some urban areas of the country, the adoption of ATES technology is thus becoming limited by the available subsurface space. This scarcity is partly caused by current approaches to ATES planning; as such, static permits tend to overestimate pumping rates and yield excessive safety margins, which in turn hamper the energy savings which could be realized by new systems. These aspects are strongly influenced by time-dependent dynamics for the adoption of ATES systems by building owners and operators, and by the variation of ATES well flows under uncertain conditions for building energy demand. In order to take these dynamics into account, previous research (Jaxa-Rozen et al., 2015) introduced a hybrid simulation architecture combining an agent-based model of ATES adoption, a Matlab control design, and a MODFLOW/SEAWAT aquifer model. This architecture was first used to study an idealized case of urban ATES development. This case evidenced a trade-off between the thermal efficiency of individual systems and the collective energy savings realized by ATES systems within a given area, which had already been suggested by other research (e.g. Sommer et al., 2015). These results also indicated that current layout guidelines may be overly conservative, and limit the adoption of new systems. The present study extends this approach to a case study of ATES planning in the city centre of Utrecht, in the Netherlands. This case is

  16. A Distributed Cooperative Dynamic Task Planning Algorithm for Multiple Satellites Based on Multi-agent Hybrid Learning

    Institute of Scientific and Technical Information of China (English)

    WANG Chong; LI Jun; JING Ning; WANG Jun; CHEN Hao

    2011-01-01

    Traditionally,heuristic re-planning algorithms are used to tackle the problem of dynamic task planning for multiple satellites.However,the traditional heuristic strategies depend on the concrete tasks,which often affect the result's optimality.Noticing that the historical information of cooperative task planning will impact the latter planning results,we propose a hybrid learning algorithrn for dynamic multi-satellite task planning,which is based on the multi-agent reinforcement learning of policy iteration and the transfer learning.The reinforcement learning strategy of each satellite is described with neural networks.The policy neural network individuals with the best topological structure and weights are found by applying co-evolutionary search iteratively.To avoid the failure of the historical learning caused by the randomly occurring observation requests,a novel approach is proposed to balance the quality and efficiency of the task planning,which converts the historical leaming strategy to the current initial learning strategy by applying the transfer learning algorithm.The simulations and analysis show the feasibility and adaptability of the proposed approach especially for the situation with randomly occurring observation requests.

  17. Diagnosis of visceral Leishmaniasis in asymptomatic dogs by the KDNA PCR-hybridization assay using noninvasive samples

    Energy Technology Data Exchange (ETDEWEB)

    Leite, Rodrigo Souza; Andrade, Antero Silva Ribeiro de [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Lab. de Radiobiologia], e-mail: rleite2005@gmail.com; Ferreira, Sydney de Almeida; Ituassu, Leonardo Trindade; Melo, Maria Norma de [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Centro de Ciencias Biologicas. Dept. de Parasitologia], e-mail: saninoalmeida@gmail.com

    2009-07-01

    The visceral leishmaniasis (VL) in Brazil is caused by Leishmania (Leishmania) chagasi and the asymptomatic dogs may transmit the parasite to sand flies vectors. The VL epidemiological control in Brazil involves the elimination of seropositive dogs, insecticide treatment and systematic treatment of human cases. Therefore, the accurate diagnosis is important in order to avoid the disease transmission or unnecessary culling of dogs. Serological tests are used for screening of dogs. However, these techniques present limitations. The Polymerase Chain Reaction (PCR) is an attractive alternative to the diagnosis in this context; but non-invasive samplings have great importance because they are simpler, painless and less resisted by dog-owners. This study aimed at evaluating conjunctival swab (CS) for canine VL diagnosis. In this methodology a sterile cotton swab is used to sampling the dog conjunctiva in both eyes. Thirty asymptomatic seropositive dogs were used. The samples were analyzed by the kDNA PCR-hybridization procedure in which the PCR products are hybridized with cloned kDNA mini-circles labeled with {sup 32}P[]dCTP. In addition, blood (B) was collected from each animal. L. chagasi was identified in 90% of CS samples and 13,6% of B samples. The high sensitivity obtained with asymptomatic dogs, in which the diagnosis is more difficult due the low number of parasites in the samples, allow concluding that the conjunctival swab associated to the kDNA PCR-hybridization assay provides a valuable alternative tool for the direct diagnosis of canine leishmaniasis. (author)

  18. Single-isocenter hybrid IMRT plans versus two-isocenter conventional plans and impact of intrafraction motion for the treatment of breast cancer with supraclavicular lymph nodes involvement.

    Science.gov (United States)

    Amoush, Ahmad; Murray, Eric; Yu, Jennifer S; Xia, Ping

    2015-07-08

    The purpose of this study was to compare the single-isocenter, four-field hybrid IMRT with the two-isocenter techniques to treat the whole breast and supraclavicular fields and to investigate the intrafraction motions in both techniques in the superior direction. Fifteen breast cancer patients who underwent lumpectomy and adjuvant radiation to the whole breast and supraclavicular (SCV) fossa at our institution were selected for this study. Two planning techniques were compared for the treatment of the breast and SCV lymph nodes. The patients were divided into three subgroups according to the whole breast volume. For the two-isocenter technique, conventional wedged or field-within-a-field tangents (FIF) were used to match with the same anterior field for the SCV region. For the single-isocenter technique, four-field hybrid IMRT was used for the tangent fields matched with a half blocked anterior field for the SCV region. To simulate the intrafraction uncertainties in the longitudinal direction for both techniques, the treatment isocenters were shifted by 1 mm and 2 mm in the superior direction. The average breast clinical tumor volume (CTV) receiving 100% (V(100%)) of the prescription dose (50 Gy) was 99.3% ± 0.5% and 96.4% ± 1.2% for the for two-isocenter and single-isocenter plans (р 20 Gy (V(20Gy)) and the heart receiving > 30 Gy (V(30Gy)) were 13.6% vs. 14.3% (р = 0.03) and 1.25% vs. 1.2% (р = 0.62), respectively. Shifting the treatment isocenter by 1 mm and 2 mm superiorly showed that the average maximum dose to 1 cc of the breast volume was 55.5 ± 1.8 Gy and 58.6 ± 4.3 Gy in the two-isocentric technique vs. 56.4 ± 2.1 Gy and 59.1 ± 5.1 Gy in the single-isocentric technique (р = 0.46, 0.87), respectively. The single-isocenter technique using four-field hybrid IMRT approach resulted in comparable plan quality as the two-isocentric technique. The single-isocenter technique is more sensitive to intra-fraction motion in the superior direction compared to

  19. Water-quality sampling plan for evaluating the distribution of bigheaded carps in the Illinois Waterway

    Science.gov (United States)

    Duncker, James J.; Terrio, Paul J.

    2017-02-27

    The two nonnative invasive bigheaded carp species (bighead carp Hypophthalmichthys nobilis and silver carp H. molitrix) that were accidentally released in the 1970s have spread widely into the rivers and waterways of the Mississippi River Basin. First detected in the lower reaches of the Illinois Waterway (IWW, the combined Illinois River-Des Plaines River-Chicago Area Waterway System) in the 1990s, bighead and silver carps moved quickly upstream, approaching the Chicago Area Waterway System. The potential of substantial negative ecological and economic impact to the Great Lakes from the presence of these species is a concern. However, since 2006, the population front of bigheaded carps has remained in the vicinity of Joliet, Illinois, near river mile 278. This reach of the IWW is characterized by stark changes in habitat, water quality, and food resources as the waterway transitions from a primarily agricultural landscape to a metropolitan and industrial canal system. This report describes a 2015 plan for sampling the IWW to establish water-quality conditions that might be contributing to the apparent stalling of the population front of bigheaded carps in this reach. A detailed description of the study plan, Lagrangian-style sampling approach, selected analytes, sampling methods and protocols are provided. Hydrographs from streamflow-gaging stations show IWW conditions during the 2015 sampling runs.

  20. Global Threat Reduction Initiative Fuel Thermo-Physical Characterization Project: Sample Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Casella, Amanda J.; Pereira, Mario M.; Steen, Franciska H.

    2013-01-01

    This sample management plan provides guidelines for sectioning, preparation, acceptance criteria, analytical path, and end-of-life disposal for the fuel element segments utilized in the Global Threat Reduction Initiative (GTRI), Fuel Thermo-Physical Characterization Project. The Fuel Thermo-Physical Characterization Project is tasked with analysis of irradiated Low Enriched Uranium (LEU) Molybdenum (U-Mo) fuel element samples to support the GTRI conversion program. Sample analysis may include optical microscopy (OM), scanning electron microscopy (SEM) fuel-surface interface analysis, gas pycnometry (density) measurements, laser flash analysis (LFA), differential scanning calorimetry (DSC), thermogravimetry and differential thermal analysis with mass spectroscopy (TG /DTA-MS), Inductively Coupled Plasma Spectrophotometry (ICP), alpha spectroscopy, and Thermal Ionization Mass Spectroscopy (TIMS). The project will utilize existing Radiochemical Processing Laboratory (RPL) operating, technical, and administrative procedures for sample receipt, processing, and analyses. Test instructions (TIs), which are documents used to provide specific details regarding the implementation of an existing RPL approved technical or operational procedure, will also be used to communicate to staff project specific parameters requested by the Principal Investigator (PI). TIs will be developed, reviewed, and issued in accordance with the latest revision of the RPL-PLN-700, RPL Operations Plan. Additionally, the PI must approve all project test instructions and red-line changes to test instructions.

  1. FIRM: Sampling-based feedback motion-planning under motion uncertainty and imperfect measurements

    KAUST Repository

    Agha-mohammadi, A.-a.

    2013-11-15

    In this paper we present feedback-based information roadmap (FIRM), a multi-query approach for planning under uncertainty which is a belief-space variant of probabilistic roadmap methods. The crucial feature of FIRM is that the costs associated with the edges are independent of each other, and in this sense it is the first method that generates a graph in belief space that preserves the optimal substructure property. From a practical point of view, FIRM is a robust and reliable planning framework. It is robust since the solution is a feedback and there is no need for expensive replanning. It is reliable because accurate collision probabilities can be computed along the edges. In addition, FIRM is a scalable framework, where the complexity of planning with FIRM is a constant multiplier of the complexity of planning with PRM. In this paper, FIRM is introduced as an abstract framework. As a concrete instantiation of FIRM, we adopt stationary linear quadratic Gaussian (SLQG) controllers as belief stabilizers and introduce the so-called SLQG-FIRM. In SLQG-FIRM we focus on kinematic systems and then extend to dynamical systems by sampling in the equilibrium space. We investigate the performance of SLQG-FIRM in different scenarios. © The Author(s) 2013.

  2. Planetary Protection, Biocontainment and Societal Issues: Planning a Sample Receiving Facility for Returned Martian Materials

    Science.gov (United States)

    Race, Margaret

    In planning for a Sample Receiving Facility (SRF), space agencies must ensure that COSPAR planetary protection requirements are met to avoid back contamination of Earth. In the United States, environmental, health and safety requirements will also apply regardless of where a facility is eventually built. The U.S. National Environmental Policy Act (NEPA, requires that NASA must prepare an environmental impact statement in advance of SRF construction to inform the public about all the potential risks, plans and reviews that will be involved. Since an SRF will likely include a BSL-4 biocontainment lab, it is instructive to examine public concerns about biocontainment that have arisen at relevant analogue facilities in order to extract lessons learned for an SRF. This paper describes findings of a recent multi-year study of 18 high-level biocontainment facilities and suggests lessons learned that are applicable to any future facilty designed to handle returned martian materials. Regardless where the SRF may be built, it will be important to develop a risk communication plan that ensures the public is informed openly, honestly, and throughout the planning, construction and operational phases of the facility.

  3. Oral health workforce planning. Part 1: Data available in a sample of FDI member countries.

    Science.gov (United States)

    Yamalik, Nermin; Ensaldo-Carrasco, Eduardo; Bourgeois, Denis

    2013-12-01

    Workforce planning is a resource to measure and compare current versus future workforce. Organised dentistry needs to focus on the benefits and the determinants and various systems of workforce planning together with the challenges, new trends and threats. The aim of the study was to identify data sources from countries relating to a selection of oral health indicators in a sample of FDI member countries. The potential for differences between developed and developing countries was also examined. A cross-sectional survey study was carried out among FDI member countries classified in developed and developing countries between October 2011 and January/February 2012. A questionnaire was developed addressing the availability of 40 selected indicators distributed in four domains. Mann-Whitney U-tests to identify differences between developed and developing countries and chi-square tests for the degree of information regularly available were carried out. There is an important lack of information about indicators relevant to oral health between FDI participating countries regardless of their level of economic development. Although not significant, the availability of indicators for developing countries showed higher variability and minimum values of zero for all domains. Surveys were the source of information more frequently reported. Standardised and reliable methodologies are needed to gather information for successful workforce planning. It is of utmost importance to increase the awareness and understanding of the member National Dental Associations regarding the role, basic elements, benefits, challenges, models and critical elements of an ideal workforce planning system.

  4. WIPP Sampling and Analysis Plan for Solid Waste Management Units and Areas of Concern

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2000-05-23

    This Sampling and Analysis Plan (SAP) has been prepared to fulfill requirements of Module VII, Section VII.M.2 and Table VII.1, requirement 4 of the Waste Isolation Pilot Plant (WIPP) Hazardous Waste Permit, NM4890139088-TSDF (the Permit); (NMED [New Mexico Environment Department], 1999a). This SAP describes the approach for investigation of the Solid Waste Management Units (SWMU) and Areas of Concern (AOC) specified in the Permit. This SAP addresses the current Permit requirements for a RCRA Facility Investigation(RFI) investigation of SWMUs and AOCs. It uses the results of previous investigations performed at WIPP and expands the investigations as required by the Permit. As an alternative to the RFI specified in Module VII of the Permit, current NMED guidance identifies an Accelerated Corrective Action Approach (ACAA) that may be used for any SWMU or AOC (NMED, 1998). This accelerated approach is used to replace the standard RFI work plan and report sequence with a more flexible decision-making approach. The ACAA process allows a facility to exit the schedule of compliance contained in the facility's Hazardous and Solid Waste Amendments (HSWA) permit module and proceed on an accelerated time frame. Thus, the ACAA process can beentered either before or after a RFI work plan. According to NMED's guidance, a facility can prepare a RFI work plan or SAP for any SWMU or AOC (NMED, 1998).

  5. Laboratory Guide for Residual Stress Sample Alignment and Experiment Planning-October 2011 Version

    Energy Technology Data Exchange (ETDEWEB)

    Cornwell, Paris A [ORNL; Bunn, Jeffrey R [ORNL; Schmidlin, Joshua E [ORNL; Hubbard, Camden R [ORNL

    2012-04-01

    The December 2010 version of the guide, ORNL/TM-2008/159, by Jeff Bunn, Josh Schmidlin, Camden Hubbard, and Paris Cornwell, has been further revised due to a major change in the GeoMagic Studio software for constructing a surface model. The Studio software update also includes a plug-in module to operate the FARO Scan Arm. Other revisions for clarity were also made. The purpose of this revision document is to guide the reader through the process of laser alignment used by NRSF2 at HFIR and VULCAN at SNS. This system was created to increase the spatial accuracy of the measurement points in a sample, reduce the use of neutron time used for alignment, improve experiment planning, and reduce operator error. The need for spatial resolution has been driven by the reduction in gauge volumes to the sub-millimeter level, steep strain gradients in some samples, and requests to mount multiple samples within a few days for relating data from each sample to a common sample coordinate system. The first step in this process involves mounting the sample on an indexer table in a laboratory set up for offline sample mounting and alignment in the same manner it would be mounted at either instrument. In the shared laboratory, a FARO ScanArm is used to measure the coordinates of points on the sample surface ('point cloud'), specific features and fiducial points. A Sample Coordinate System (SCS) needs to be established first. This is an advantage of the technique because the SCS can be defined in such a way to facilitate simple definition of measurement points within the sample. Next, samples are typically mounted to a frame of 80/20 and fiducial points are attached to the sample or frame then measured in the established sample coordinate system. The laser scan probe on the ScanArm can then be used to scan in an 'as-is' model of the sample as well as mounting hardware. GeoMagic Studio 12 is the software package used to construct the model from the point cloud the

  6. A scalable method for parallelizing sampling-based motion planning algorithms

    KAUST Repository

    Jacobs, Sam Ade

    2012-05-01

    This paper describes a scalable method for parallelizing sampling-based motion planning algorithms. It subdivides configuration space (C-space) into (possibly overlapping) regions and independently, in parallel, uses standard (sequential) sampling-based planners to construct roadmaps in each region. Next, in parallel, regional roadmaps in adjacent regions are connected to form a global roadmap. By subdividing the space and restricting the locality of connection attempts, we reduce the work and inter-processor communication associated with nearest neighbor calculation, a critical bottleneck for scalability in existing parallel motion planning methods. We show that our method is general enough to handle a variety of planning schemes, including the widely used Probabilistic Roadmap (PRM) and Rapidly-exploring Random Trees (RRT) algorithms. We compare our approach to two other existing parallel algorithms and demonstrate that our approach achieves better and more scalable performance. Our approach achieves almost linear scalability on a 2400 core LINUX cluster and on a 153,216 core Cray XE6 petascale machine. © 2012 IEEE.

  7. Treatment of breast cancer with simultaneous integrated boost in hybrid plan technique. Influence of flattening filter-free beams

    Energy Technology Data Exchange (ETDEWEB)

    Bahrainy, Marzieh; Kretschmer, Matthias; Joest, Vincent; Kasch, Astrid; Wuerschmidt, Florian; Dahle, Joerg; Lorenzen, Joern [Radiologische Allianz, Hamburg (Germany)

    2016-05-15

    The present study compares in silico treatment plans using hybrid plan technique during hypofractionated radiation of mammary carcinoma with simultaneous integrated boost (SIB). The influence of 6 MV photon radiation in flattening filter free (FFF) mode against the clinical standard flattening filter (FF) mode is to be examined. RT planning took place with FF and FFF radiation plans for 10 left-sided breast cancer patients. Hybrid plans were realised with two tangential IMRT fields and one VMAT field. The dose prescription was in line with the guidelines in the ARO-2010-01 study. The dosimetric verification took place with a manufacturer-independent measurement system. Required dose prescriptions for the planning target volumes (PTV) were achieved for both groups. The average dose values of the ipsi- and contralateral lung and the heart did not differ significantly. The overall average incidental dose to the left anterior descending artery (LAD) of 8.24 ± 3.9 Gy in the FFF group and 9.05 ± 3.7 Gy in the FF group (p < 0.05) were found. The dosimetric verifications corresponded to the clinical requirements. FFF-based RT plans reduced the average treatment time by 17 s/fraction. In comparison to the FF-based hybrid plan technique the FFF mode allows further reduction of the average LAD dose for comparable target volume coverage without adverse low-dose exposure of contralateral structures. The combination of hybrid plan technique and 6 MV photon radiation in the FFF mode is suitable for use with hypofractionated dose schemes. The increased dose rate allows a substantial reduction of treatment time and thus beneficial application of the deep inspiration breath hold technique. (orig.) [German] Vergleich der ''In-silico''-Bestrahlungsplaene der klinisch etablierten Hybridplan-Technik bei hypofraktionierter Bestrahlung des Mammakarzinoms mit simultan integriertem Boost (SIB). Untersucht wird der Einfluss von 6MV-Photonenstrahlung im Flattening

  8. Spectrum of Cytogenomic Abnormalities Revealed by Array Comparative Genomic Hybridization on Products of Conception Culture Failure and Normal Karyotype Samples.

    Science.gov (United States)

    Zhou, Qinghua; Wu, Shen-Yin; Amato, Katherine; DiAdamo, Autumn; Li, Peining

    2016-03-20

    Approximately 30% of pregnancies after implantation end up in spontaneous abortions, and 50% of them are caused by chromosomal abnormalities. However, the spectrum of genomic copy number variants (CNVs) in products of conception (POC) and the underlying gene-dosage-sensitive mechanisms causing spontaneous abortions remain largely unknown. In this study, array comparative genomic hybridization (aCGH) analysis was performed as a salvage procedure for 128 POC culture failure (POC-CF) samples and as a supplemental procedure for 106 POC normal karyotype (POC-NK) samples. Chromosomal abnormalities were detected in 10% of POC-CF and pathogenic CNVs were detected in 3.9% of POC-CF and 5.7% of POC-NK samples. Compiled results from this study and relevant case series through a literature review demonstrated an abnormality detection rate (ADR) of 35% for chromosomal abnormalities in POC-CF samples, 3.7% for pathogenic CNVs in POC-CF samples, and 4.6% for pathogenic CNVs in POC-NK samples. Ingenuity Pathway Analysis (IPA) was performed on the genes from pathogenic CNVs found in POC samples. The denoted primary gene networks suggested that apoptosis and cell proliferation pathways are involved in miscarriage. In summary, a similar spectrum of cytogenomic abnormalities was observed in POC culture success and POC-CF samples. A threshold effect correlating the number of dosage-sensitive genes in a chromosome with the observed frequency of autosomal trisomy is proposed. A rationalized approach using firstly fluorescence in situ hybridization (FISH) testing with probes of chromosomes X/Y/18, 13/21, and 15/16/22 for common aneuploidies and polyploidies and secondly aCGH for other cytogenomic abnormalities is recommended for POC-CF samples.

  9. Mission Planning and Decision Support for Underwater Glider Networks: A Sampling on-Demand Approach.

    Science.gov (United States)

    Ferri, Gabriele; Cococcioni, Marco; Alvarez, Alberto

    2015-12-26

    This paper describes an optimal sampling approach to support glider fleet operators and marine scientists during the complex task of planning the missions of fleets of underwater gliders. Optimal sampling, which has gained considerable attention in the last decade, consists in planning the paths of gliders to minimize a specific criterion pertinent to the phenomenon under investigation. Different criteria (e.g., A, G, or E optimality), used in geosciences to obtain an optimum design, lead to different sampling strategies. In particular, the A criterion produces paths for the gliders that minimize the overall level of uncertainty over the area of interest. However, there are commonly operative situations in which the marine scientists may prefer not to minimize the overall uncertainty of a certain area, but instead they may be interested in achieving an acceptable uncertainty sufficient for the scientific or operational needs of the mission. We propose and discuss here an approach named sampling on-demand that explicitly addresses this need. In our approach the user provides an objective map, setting both the amount and the geographic distribution of the uncertainty to be achieved after assimilating the information gathered by the fleet. A novel optimality criterion, called A η , is proposed and the resulting minimization problem is solved by using a Simulated Annealing based optimizer that takes into account the constraints imposed by the glider navigation features, the desired geometry of the paths and the problems of reachability caused by ocean currents. This planning strategy has been implemented in a Matlab toolbox called SoDDS (Sampling on-Demand and Decision Support). The tool is able to automatically download the ocean fields data from MyOcean repository and also provides graphical user interfaces to ease the input process of mission parameters and targets. The results obtained by running SoDDS on three different scenarios are provided and show that So

  10. Mission Planning and Decision Support for Underwater Glider Networks: A Sampling on-Demand Approach

    Directory of Open Access Journals (Sweden)

    Gabriele Ferri

    2015-12-01

    Full Text Available This paper describes an optimal sampling approach to support glider fleet operators and marine scientists during the complex task of planning the missions of fleets of underwater gliders. Optimal sampling, which has gained considerable attention in the last decade, consists in planning the paths of gliders to minimize a specific criterion pertinent to the phenomenon under investigation. Different criteria (e.g., A, G, or E optimality, used in geosciences to obtain an optimum design, lead to different sampling strategies. In particular, the A criterion produces paths for the gliders that minimize the overall level of uncertainty over the area of interest. However, there are commonly operative situations in which the marine scientists may prefer not to minimize the overall uncertainty of a certain area, but instead they may be interested in achieving an acceptable uncertainty sufficient for the scientific or operational needs of the mission. We propose and discuss here an approach named sampling on-demand that explicitly addresses this need. In our approach the user provides an objective map, setting both the amount and the geographic distribution of the uncertainty to be achieved after assimilating the information gathered by the fleet. A novel optimality criterion, called A η , is proposed and the resulting minimization problem is solved by using a Simulated Annealing based optimizer that takes into account the constraints imposed by the glider navigation features, the desired geometry of the paths and the problems of reachability caused by ocean currents. This planning strategy has been implemented in a Matlab toolbox called SoDDS (Sampling on-Demand and Decision Support. The tool is able to automatically download the ocean fields data from MyOcean repository and also provides graphical user interfaces to ease the input process of mission parameters and targets. The results obtained by running SoDDS on three different scenarios are provided

  11. Sample size planning with the cost constraint for testing superiority and equivalence of two independent groups.

    Science.gov (United States)

    Guo, Jiin-Huarng; Chen, Hubert J; Luh, Wei-Ming

    2011-11-01

    The allocation of sufficient participants into different experimental groups for various research purposes under given constraints is an important practical problem faced by researchers. We address the problem of sample size determination between two independent groups for unequal and/or unknown variances when both the power and the differential cost are taken into consideration. We apply the well-known Welch approximate test to derive various sample size allocation ratios by minimizing the total cost or, equivalently, maximizing the statistical power. Two types of hypotheses including superiority/non-inferiority and equivalence of two means are each considered in the process of sample size planning. A simulation study is carried out and the proposed method is validated in terms of Type I error rate and statistical power. As a result, the simulation study reveals that the proposed sample size formulas are very satisfactory under various variances and sample size allocation ratios. Finally, a flowchart, tables, and figures of several sample size allocations are presented for practical reference.

  12. Sample size planning for composite reliability coefficients: accuracy in parameter estimation via narrow confidence intervals.

    Science.gov (United States)

    Terry, Leann; Kelley, Ken

    2012-11-01

    Composite measures play an important role in psychology and related disciplines. Composite measures almost always have error. Correspondingly, it is important to understand the reliability of the scores from any particular composite measure. However, the point estimates of the reliability of composite measures are fallible and thus all such point estimates should be accompanied by a confidence interval. When confidence intervals are wide, there is much uncertainty in the population value of the reliability coefficient. Given the importance of reporting confidence intervals for estimates of reliability, coupled with the undesirability of wide confidence intervals, we develop methods that allow researchers to plan sample size in order to obtain narrow confidence intervals for population reliability coefficients. We first discuss composite reliability coefficients and then provide a discussion on confidence interval formation for the corresponding population value. Using the accuracy in parameter estimation approach, we develop two methods to obtain accurate estimates of reliability by planning sample size. The first method provides a way to plan sample size so that the expected confidence interval width for the population reliability coefficient is sufficiently narrow. The second method ensures that the confidence interval width will be sufficiently narrow with some desired degree of assurance (e.g., 99% assurance that the 95% confidence interval for the population reliability coefficient will be less than W units wide). The effectiveness of our methods was verified with Monte Carlo simulation studies. We demonstrate how to easily implement the methods with easy-to-use and freely available software. ©2011 The British Psychological Society.

  13. Scheduling Algorithm for Mission Planning and Logistics Evaluation (SAMPLE). Volume 3: The GREEDY algorithm

    Science.gov (United States)

    Dupnick, E.; Wiggins, D.

    1980-01-01

    The functional specifications, functional design and flow, and the program logic of the GREEDY computer program are described. The GREEDY program is a submodule of the Scheduling Algorithm for Mission Planning and Logistics Evaluation (SAMPLE) program and has been designed as a continuation of the shuttle Mission Payloads (MPLS) program. The MPLS uses input payload data to form a set of feasible payload combinations; from these, GREEDY selects a subset of combinations (a traffic model) so all payloads can be included without redundancy. The program also provides the user a tutorial option so that he can choose an alternate traffic model in case a particular traffic model is unacceptable.

  14. Technology Development and Advanced Planning for Curation of Returned Mars Samples

    Science.gov (United States)

    Lindstrom, D. J.; Allen, C. C.

    2002-05-01

    NASA/Johnson Space Center (JSC) curates extraterrestrial samples, providing the international science community with lunar rock and soil returned by the Apollo astronauts, meteorites collected in Antarctica, cosmic dust collected in the stratosphere, and hardware exposed to the space environment. Curation comprises initial characterization of new samples, preparation and allocation of samples for research, and clean, secure long-term storage. The foundations of this effort are the specialized cleanrooms (class 10 to 10,000) for each of the four types of materials, the supporting facilities, and the people, many of whom have been doing detailed work in clean environments for decades. JSC is also preparing to curate the next generation of extraterrestrial samples. These include samples collected from the solar wind, a comet, and an asteroid. Early planning and R&D are underway to support post-mission sample handling and curation of samples returned from Mars. One of the strong scientific reasons for returning samples from Mars is to search for evidence of current or past life in the samples. Because of the remote possibility that the samples may contain life forms that are hazardous to the terrestrial biosphere, the National Research Council has recommended that all samples returned from Mars be kept under strict biological containment until tests show that they can safely be released to other laboratories. It is possible that Mars samples may contain only scarce or subtle traces of life or prebiotic chemistry that could readily be overwhelmed by terrestrial contamination. Thus, the facilities used to contain, process, and analyze samples from Mars must have a combination of high-level biocontainment and organic / inorganic chemical cleanliness that is unprecedented. JSC has been conducting feasibility studies and developing designs for a sample receiving facility that would offer biocontainment at least the equivalent of current maximum containment BSL-4 (Bio

  15. A hybrid Planning Method for Transmission Network in a Deregulated Enviroment

    DEFF Research Database (Denmark)

    Xu, Zhao; Dong, Zhaoyang; Poulsen, Kit

    2006-01-01

    The reconstruction of power industries has brought fundamental changes to both power system operation and planning. This paper presents a new planning method using a multi-objective optimization (MOOP) technique, as well as human knowledge, to expand the transmission network in open-access schemes....... The method starts with a candidate pool of feasible expansion plans. Consequent selection of the best candidates is carried out through a MOOP approach, of which multiple objectives are tackled simultaneously, aiming at integrating the market operation and planning as one unified process in context...

  16. A hybrid particle swarm optimization approach with neural network and set pair analysis for transmission network planning

    Institute of Scientific and Technical Information of China (English)

    刘吉成; 颜苏莉; 乞建勋

    2008-01-01

    Transmission network planning (TNP) is a large-scale, complex, with more non-linear discrete variables and the multi-objective constrained optimization problem. In the optimization process, the line investment, network reliability and the network loss are the main objective of transmission network planning. Combined with set pair analysis (SPA), particle swarm optimization (PSO), neural network (NN), a hybrid particle swarm optimization model was established with neural network and set pair analysis for transmission network planning (HPNS). Firstly, the contact degree of set pair analysis was introduced, the traditional goal set was converted into the collection of the three indicators including the identity degree, difference agree and contrary degree. On this bases, using shi(H), the three objective optimization problem was converted into single objective optimization problem. Secondly, using the fast and efficient search capabilities of PSO, the transmission network planning model based on set pair analysis was optimized. In the process of optimization, by improving the BP neural network constantly training so that the value of the fitness function of PSO becomes smaller in order to obtain the optimization program fitting the three objectives better. Finally, compared HPNS with PSO algorithm and the classic genetic algorithm, HPNS increased about 23% efficiency than THA, raised about 3.7% than PSO and improved about 2.96% than GA.

  17. Design-based stereology: Planning, volumetry and sampling are crucial steps for a successful study.

    Science.gov (United States)

    Tschanz, Stefan; Schneider, Jan Philipp; Knudsen, Lars

    2014-01-01

    Quantitative data obtained by means of design-based stereology can add valuable information to studies performed on a diversity of organs, in particular when correlated to functional/physiological and biochemical data. Design-based stereology is based on a sound statistical background and can be used to generate accurate data which are in line with principles of good laboratory practice. In addition, by adjusting the study design an appropriate precision can be achieved to find relevant differences between groups. For the success of the stereological assessment detailed planning is necessary. In this review we focus on common pitfalls encountered during stereological assessment. An exemplary workflow is included, and based on authentic examples, we illustrate a number of sampling principles which can be implemented to obtain properly sampled tissue blocks for various purposes. Copyright © 2013 Elsevier GmbH. All rights reserved.

  18. Phase 1 Characterization sampling and analysis plan West Valley demonstration project.

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, R. L. (Environmental Science Division)

    2011-06-30

    The Phase 1 Characterization Sampling and Analysis Plan (CSAP) provides details about environmental data collection that will be taking place to support Phase 1 decommissioning activities described in the Phase 1 Decommissioning Plan for the West Valley Demonstration Project, Revision 2 (Phase I DP; DOE 2009). The four primary purposes of CSAP data collection are: (1) pre-design data collection, (2) remedial support, (3) post-remediation status documentation, and (4) Phase 2 decision-making support. Data collection to support these four main objectives is organized into two distinct data collection efforts. The first is data collection that will take place prior to the initiation of significant Phase 1 decommissioning activities (e.g., the Waste Management Area [WMA] 1 and WMA 2 excavations). The second is data collection that will occur during and immediately after environmental remediation in support of remediation activities. Both data collection efforts have a set of well-defined objectives that encompass the data needs of the four main CSAP data collection purposes detailed in the CSAP. The main body of the CSAP describes the overall data collection strategies that will be used to satisfy data collection objectives. The details of pre-remediation data collection are organized by WMA. The CSAP contains an appendix for each WMA that describes the details of WMA-specific pre-remediation data collection activities. The CSAP is intended to expand upon the data collection requirements identified in the Phase 1 Decommissioning Plan. The CSAP is intended to tightly integrate with the Phase 1 Final Status Survey Plan (FSSP). Data collection described by the CSAP is consistent with the FSSP where appropriate and to the extent possible.

  19. Innovation in Doctoral Degrees Designed for Adult Learners: A Hybrid Model in Personal Financial Planning

    Science.gov (United States)

    Grable, John E.

    2011-01-01

    Innovation in doctoral degree program development and delivery provides an effective counterpoint to the expert-apprentice model established in the Middle Ages. The author outlines the importance of innovation in reaching adult learners and describes an innovative hybrid PhD program designed to allow aspiring doctoral adult-age students to pursue…

  20. Innovation in Doctoral Degrees Designed for Adult Learners: A Hybrid Model in Personal Financial Planning

    Science.gov (United States)

    Grable, John E.

    2011-01-01

    Innovation in doctoral degree program development and delivery provides an effective counterpoint to the expert-apprentice model established in the Middle Ages. The author outlines the importance of innovation in reaching adult learners and describes an innovative hybrid PhD program designed to allow aspiring doctoral adult-age students to pursue…

  1. Enumerative and binomial sequential sampling plans for the multicolored Asian lady beetle (Coleoptera: Coccinellidae) in wine grapes.

    Science.gov (United States)

    Galvan, T L; Burkness, E C; Hutchison, W D

    2007-06-01

    To develop a practical integrated pest management (IPM) system for the multicolored Asian lady beetle, Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae), in wine grapes, we assessed the spatial distribution of H. axyridis and developed eight sampling plans to estimate adult density or infestation level in grape clusters. We used 49 data sets collected from commercial vineyards in 2004 and 2005, in Minnesota and Wisconsin. Enumerative plans were developed using two precision levels (0.10 and 0.25); the six binomial plans reflected six unique action thresholds (3, 7, 12, 18, 22, and 31% of cluster samples infested with at least one H. axyridis). The spatial distribution of H. axyridis in wine grapes was aggregated, independent of cultivar and year, but it was more randomly distributed as mean density declined. The average sample number (ASN) for each sampling plan was determined using resampling software. For research purposes, an enumerative plan with a precision level of 0.10 (SE/X) resulted in a mean ASN of 546 clusters. For IPM applications, the enumerative plan with a precision level of 0.25 resulted in a mean ASN of 180 clusters. In contrast, the binomial plans resulted in much lower ASNs and provided high probabilities of arriving at correct "treat or no-treat" decisions, making these plans more efficient for IPM applications. For a tally threshold of one adult per cluster, the operating characteristic curves for the six action thresholds provided binomial sequential sampling plans with mean ASNs of only 19-26 clusters, and probabilities of making correct decisions between 83 and 96%. The benefits of the binomial sampling plans are discussed within the context of improving IPM programs for wine grapes.

  2. UMTRA project water sampling and analysis plan, Ambrosia Lake, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    This water sampling and analysis plan (WSAP) provides the basis for ground water sampling at the Ambrosia Lake Uranium Mill Tailings Remedial Action (UMTRA) Project site during fiscal year 1994. It identifies and justifies the sampling locations, analytical parameters, detection limits, and sampling frequency for the monitoring locations and will be updated annually. The Ambrosia Lake site is in McKinley County, New Mexico, about 40 kilometers (km) (25 miles [mi]) north of Grants, New Mexico, and 1.6 km (1 mi) east of New Mexico Highway 509 (Figure 1.1). The town closest to the tailings pile is San Mateo, about 16 km ( 10 mi) southeast (Figure 1.2). The former mill and tailings pile are in Section 28, and two holding ponds are in Section 33, Township 14 North, Range 9 West. The site is shown on the US Geological Survey (USGS) map (USGS, 1980). The site is approximately 2100 meters (m) (7000 feet [ft]) above sea level.

  3. Seasonal phenology, spatial distribution, and sampling plan for the invasive mealybug Phenacoccus peruvianus (Hemiptera: Pseudococcidae).

    Science.gov (United States)

    Beltrá, A; Garcia-Marí, F; Soto, A

    2013-06-01

    Phlenacoccus peruvianus Granara de Willink (Hemiptera: Pseudococcidae) is an invasive mealybug of Neotropical origin. In recent years it has invaded the Mediterranean Basin causing significant damages in bougainvillea and other ornamental plants. This article examines its phenology, location on the plant and spatial distribution, and presents a sampling plan to determine P. peruvianus population density for the management of this mealybug in southern Europe. Six urban green spaces with bougainvillea plants were periodically surveyed between March 2008 and September 2010 in eastern Spain, sampling bracts, leaves, and twigs. Our results show that P. peruvianus abundance was high in spring and summer, declining to almost undetectable levels in autumn and winter. The mealybugs showed a preference for settling on bracts and there were no significant migrations between plant organs. P. peruvianus showed a highly aggregated distribution on bracts, leaves, and twigs. We recommend abinomial sampling of 200 leaves and an action threshold of 55% infested leaves for integrated pest management purposes on urban landscapes and enumerative sampling for ornamental nursery management and additional biological studies.

  4. Microbiological sampling plan based on risk classification to verify supplier selection and production of served meals in food service operation.

    Science.gov (United States)

    Lahou, Evy; Jacxsens, Liesbeth; Van Landeghem, Filip; Uyttendaele, Mieke

    2014-08-01

    Food service operations are confronted with a diverse range of raw materials and served meals. The implementation of a microbial sampling plan in the framework of verification of suppliers and their own production process (functionality of their prerequisite and HACCP program), demands selection of food products and sampling frequencies. However, these are often selected without a well described scientifically underpinned sampling plan. Therefore, an approach on how to set-up a focused sampling plan, enabled by a microbial risk categorization of food products, for both incoming raw materials and meals served to the consumers is presented. The sampling plan was implemented as a case study during a one-year period in an institutional food service operation to test the feasibility of the chosen approach. This resulted in 123 samples of raw materials and 87 samples of meal servings (focused on high risk categorized food products) which were analyzed for spoilage bacteria, hygiene indicators and food borne pathogens. Although sampling plans are intrinsically limited in assessing the quality and safety of sampled foods, it was shown to be useful to reveal major non-compliances and opportunities to improve the food safety management system in place. Points of attention deduced in the case study were control of Listeria monocytogenes in raw meat spread and raw fish as well as overall microbial quality of served sandwiches and salads.

  5. Evaluation of PCR, DNA hybridization and immunomagnetic separation - PCR for detection of Burkholderia mallei in artificially inoculated environmental samples.

    Science.gov (United States)

    Merwyn, S; Kumar, S; Agarwal, G S; Rai, G P

    2010-06-01

    Glanders is highly contagious disease of equines, caused by Burkholderia mallei. The disease though rare, can be transmitted to humans. Here, we report a strategy for rapid detection of B. mallei from environmental samples. Different bacteriological media were evaluated and brain heart infusion broth medium with selective supplements (BHIB-SS) of penicillin (200 U/ml) and crystal violet (1:10,00000) was found to support the maximum growth of B. mallei even in the presence of other bacteria like Escherichia coli and Staphylococcus aureus. A polymerase chain reaction (PCR) and a DNA hybridization method was standardized for 823 bp specific dNA sequence of B. mallei. To enable the quicker and direct enrichment of B. mallei bacteria from environmental samples, an immunomagnetic separation (IMS) method was also standardized. Water, husk, grass and gram samples were artificially contaminated by B. mallei bacteria and after enrichment of B. mallei in BHIB-SS, detection was carried out by PCR and DNA hybridization. PCR was found to be a better method of the two with a detection limit of 10(4)-10(6) CFU/ml (6 h enrichment in BHIB-SS) in water and other particulate matrices. Detection by PCR in the above samples without enrichment in BHIBSS was carried out following IMS where the detection limit was about 1-2 log higher than PCR following enrichment in BHIB-SS. We recommend PCR for 823 bp for detection of B. mallei from environmental samples either following enrichment in BHIB-SS or IMS. IMS-PCR method may be preferred in situations where numbers of B. mallei bacteria are expected to be high and results are required in short time.

  6. A hybrid solution using computational prediction and measured data to accurately determine process corrections with reduced overlay sampling

    Science.gov (United States)

    Noyes, Ben F.; Mokaberi, Babak; Mandoy, Ram; Pate, Alex; Huijgen, Ralph; McBurney, Mike; Chen, Owen

    2017-03-01

    Reducing overlay error via an accurate APC feedback system is one of the main challenges in high volume production of the current and future nodes in the semiconductor industry. The overlay feedback system directly affects the number of dies meeting overlay specification and the number of layers requiring dedicated exposure tools through the fabrication flow. Increasing the former number and reducing the latter number is beneficial for the overall efficiency and yield of the fabrication process. An overlay feedback system requires accurate determination of the overlay error, or fingerprint, on exposed wafers in order to determine corrections to be automatically and dynamically applied to the exposure of future wafers. Since current and future nodes require correction per exposure (CPE), the resolution of the overlay fingerprint must be high enough to accommodate CPE in the overlay feedback system, or overlay control module (OCM). Determining a high resolution fingerprint from measured data requires extremely dense overlay sampling that takes a significant amount of measurement time. For static corrections this is acceptable, but in an automated dynamic correction system this method creates extreme bottlenecks for the throughput of said system as new lots have to wait until the previous lot is measured. One solution is using a less dense overlay sampling scheme and employing computationally up-sampled data to a dense fingerprint. That method uses a global fingerprint model over the entire wafer; measured localized overlay errors are therefore not always represented in its up-sampled output. This paper will discuss a hybrid system shown in Fig. 1 that combines a computationally up-sampled fingerprint with the measured data to more accurately capture the actual fingerprint, including local overlay errors. Such a hybrid system is shown to result in reduced modelled residuals while determining the fingerprint, and better on-product overlay performance.

  7. Optimization process planning using hybrid genetic algorithm and intelligent search for job shop machining.

    Science.gov (United States)

    Salehi, Mojtaba; Bahreininejad, Ardeshir

    2011-08-01

    Optimization of process planning is considered as the key technology for computer-aided process planning which is a rather complex and difficult procedure. A good process plan of a part is built up based on two elements: (1) the optimized sequence of the operations of the part; and (2) the optimized selection of the machine, cutting tool and Tool Access Direction (TAD) for each operation. In the present work, the process planning is divided into preliminary planning, and secondary/detailed planning. In the preliminary stage, based on the analysis of order and clustering constraints as a compulsive constraint aggregation in operation sequencing and using an intelligent searching strategy, the feasible sequences are generated. Then, in the detailed planning stage, using the genetic algorithm which prunes the initial feasible sequences, the optimized operation sequence and the optimized selection of the machine, cutting tool and TAD for each operation based on optimization constraints as an additive constraint aggregation are obtained. The main contribution of this work is the optimization of sequence of the operations of the part, and optimization of machine selection, cutting tool and TAD for each operation using the intelligent search and genetic algorithm simultaneously.

  8. 2017 Annual Terrestrial Sampling Plan for Sandia National Laboratories/New Mexico on Kirtland Air Force Base

    Energy Technology Data Exchange (ETDEWEB)

    Griffith, Stacy R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    The 2017 Annual Terrestrial Sampling Plan for Sandia National Laboratories/New Mexico on Kirtland Air Force Base has been prepared in accordance with the “Letter of Agreement Between Department of Energy, National Nuclear Security Administration, Sandia Field Office (DOE/NNSA/SFO) and 377th Air Base Wing (ABW), Kirtland Air Force Base (KAFB) for Terrestrial Sampling” (signed January 2017), Sandia National Laboratories, New Mexico (SNL/NM). The Letter of Agreement requires submittal of an annual terrestrial sampling plan.

  9. Development of a binomial sampling plan for the carob moth (Lepidoptera: Pyralidae), a pest of California dates.

    Science.gov (United States)

    Park, Jung-Joon; Perring, Thomas M

    2010-08-01

    The seasonal density fluctuations of the carob moth, Ectomyelois ceratoniae (Zeller) (Lepidoptera: Pyralidae), were determined in a commercial date, Phoenix dactylifera L. garden. Four fruit categories (axil, ground, abscised green, and abscised brown) were sampled, and two carob moth life stages, eggs and immatures (larvae and pupae combined), were evaluated on these fruits. Based on the relative consistency of these eight sampling units (four fruit categories and two carob moth stages), four were used for the development of a binomial sampling plan. The average number of carob moth eggs and immatures on ground and abscised brown fruit was estimated from the proportion of infested fruit, and these binomial models were evaluated for model fitness and precision. These analyses suggested that the best sampling plan should consist of abscised brown dates and carob moth immatures by using a sample size of 100 dates. The performance of this binomial plan was evaluated further using a resampling protocol with 25 independent data sets at action thresholds of 7, 10, and 15% to represent light, medium and severe infestations, respectively. Results from the resampling program suggested that increasing sample size from 100 to 150 dates improved the precision of the binomial sampling plan. Use of this sampling plan will be the cornerstone of an integrated pest management program for carob moth in dates.

  10. Indoor Pedestrian Navigation Based on Hybrid Route Planning and Location Modeling

    DEFF Research Database (Denmark)

    Schougaard, Kari Rye; Grønbæk, Kaj; Scharling, Tejs

    2012-01-01

    This paper introduces methods and services called PerPosNav for development of custom indoor pedestrian navigation applications to be deployed on a variety of platforms. PerPosNav combines symbolic and geometry based modeling of buildings, and in turn combines graph-based and geometric route...... computation. The paper argues why these hybrid approaches are necessary to handle the challenges of in-door pedestrian navigation...

  11. Multi-Period Optimization Model for Electricity Generation Planning Considering Plug-in Hybrid Electric Vehicle Penetration

    Directory of Open Access Journals (Sweden)

    Lena Ahmadi

    2015-05-01

    Full Text Available One of the main challenges for widespread penetration of plug-in hybrid electric vehicles (PHEVs is their impact on the electricity grid. The energy sector must anticipate and prepare for this extra demand and implement long-term planning for electricity production. In this paper, the additional electricity demand on the Ontario electricity grid from charging PHEVs is incorporated into an electricity production planning model. A case study pertaining to Ontario energy planning is considered to optimize the value of the cost of the electricity over sixteen years (2014–2030. The objective function consists of the fuel costs, fixed and variable operating and maintenance costs, capital costs for new power plants, and the retrofit costs of existing power plants. Five different case studies are performed with different PHEVs penetration rates, types of new power plants, and CO2 emission constraints. Among all the cases studied, the one requiring the most new capacity, (~8748 MW, is assuming the base case with 6% reduction in CO2 in year 2018 and high PHEV penetration. The next highest one is the base case, plus considering doubled NG prices, PHEV medium penetration rate and no CO2 emissions reduction target with an increase of 34.78% in the total installed capacity in 2030. Furthermore, optimization results indicate that by not utilizing coal power stations the CO2 emissions are the lowest: ~500 tonnes compared to ~900 tonnes when coal is permitted.

  12. Whole-body hybrid imaging concept for the integration of PET/MR into radiation therapy treatment planning

    Science.gov (United States)

    Paulus, Daniel H.; Oehmigen, Mark; Grueneisen, Johannes; Umutlu, Lale; Quick, Harald H.

    2016-05-01

    Modern radiation therapy (RT) treatment planning is based on multimodality imaging. With the recent availability of whole-body PET/MR hybrid imaging new opportunities arise to improve target volume delineation in RT treatment planning. This, however, requires dedicated RT equipment for reproducible patient positioning on the PET/MR system, which has to be compatible with MR and PET imaging. A prototype flat RT table overlay, radiofrequency (RF) coil holders for head imaging, and RF body bridges for body imaging were developed and tested towards PET/MR system integration. Attenuation correction (AC) of all individual RT components was performed by generating 3D CT-based template models. A custom-built program for μ-map generation assembles all AC templates depending on the presence and position of each RT component. All RT devices were evaluated in phantom experiments with regards to MR and PET imaging compatibility, attenuation correction, PET quantification, and position accuracy. The entire RT setup was then evaluated in a first PET/MR patient study on five patients at different body regions. All tested devices are PET/MR compatible and do not produce visible artifacts or disturb image quality. The RT components showed a repositioning accuracy of better than 2 mm. Photon attenuation of  -11.8% in the top part of the phantom was observable, which was reduced to  -1.7% with AC using the μ-map generator. Active lesions of 3 subjects were evaluated in terms of SUVmean and an underestimation of  -10.0% and  -2.4% was calculated without and with AC of the RF body bridges, respectively. The new dedicated RT equipment for hybrid PET/MR imaging enables acquisitions in all body regions. It is compatible with PET/MR imaging and all hardware components can be corrected in hardware AC by using the suggested μ-map generator. These developments provide the technical and methodological basis for integration of PET/MR hybrid imaging into RT planning.

  13. Preconception health: awareness, planning, and communication among a sample of US men and women.

    Science.gov (United States)

    Mitchell, Elizabeth W; Levis, Denise M; Prue, Christine E

    2012-01-01

    It is important to educate both men and women about preconception health (PCH), but limited research exists in this area. This paper examines men's and women's awareness of exposure to PCH information and of specific PCH behaviors, PCH planning, and PCH discussions with their partners. Data from Porter Novelli's 2007 Healthstyles survey were used. Women and men of reproductive age were included in the analysis (n = 2,736) to understand their awareness, planning, and conversations around PCH. Only 27.9% of women and men reported consistently using an effective birth control method. The majority of men (52%) and women (43%) were unaware of any exposure to PCH messages; few received information from their health care provider. Women were more aware than men of specific pre-pregnancy health behaviors. Women in the sample reported having more PCH conversations with their partners than did men. PCH education should focus on both women and men. Communication about PCH is lacking, both between couples and among men and women and their health care providers. PCH education might benefit from brand development so that consumers know what to ask for and providers know what to deliver.

  14. Whole arm manipulation planning based on feedback velocity fields and sampling-based techniques.

    Science.gov (United States)

    Talaei, B; Abdollahi, F; Talebi, H A; Omidi Karkani, E

    2013-09-01

    Changing the configuration of a cooperative whole arm manipulator is not easy while enclosing an object. This difficulty is mainly because of risk of jamming caused by kinematic constraints. To reduce this risk, this paper proposes a feedback manipulation planning algorithm that takes grasp kinematics into account. The idea is based on a vector field that imposes perturbation in object motion inducing directions when the movement is considerably along manipulator redundant directions. Obstacle avoidance problem is then considered by combining the algorithm with sampling-based techniques. As experimental results confirm, the proposed algorithm is effective in avoiding jamming as well as obstacles for a 6-DOF dual arm whole arm manipulator. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  15. Fixed-Precision Sequential Sampling Plans for Estimating Alfalfa Caterpillar, Colias lesbia, Egg Density in Alfalfa, Medicago sativa, Fields in Córdoba, Argentina

    National Research Council Canada - National Science Library

    Gerardo V. Serra; Norma C. La Porta; Susana Avalos; Vilma Mazzuferi

    2013-01-01

    .... Using Resampling for Validation of Sampling Plans software, 12 additional independent data sets were used to validate the sequential sampling plan with precision levels of 0.10 and 0.25 (SE/mean), respectively...

  16. Organ sample generator for expected treatment dose construction and adaptive inverse planning optimization

    Energy Technology Data Exchange (ETDEWEB)

    Nie Xiaobo; Liang Jian; Yan Di [Department of Radiation Oncology, Beaumont Health System, Royal Oak, Michigan 48073 (United States)

    2012-12-15

    Purpose: To create an organ sample generator (OSG) for expected treatment dose construction and adaptive inverse planning optimization. The OSG generates random samples of organs of interest from a distribution obeying the patient specific organ variation probability density function (PDF) during the course of adaptive radiotherapy. Methods: Principle component analysis (PCA) and a time-varying least-squares regression (LSR) method were used on patient specific geometric variations of organs of interest manifested on multiple daily volumetric images obtained during the treatment course. The construction of the OSG includes the determination of eigenvectors of the organ variation using PCA, and the determination of the corresponding coefficients using time-varying LSR. The coefficients can be either random variables or random functions of the elapsed treatment days depending on the characteristics of organ variation as a stationary or a nonstationary random process. The LSR method with time-varying weighting parameters was applied to the precollected daily volumetric images to determine the function form of the coefficients. Eleven h and n cancer patients with 30 daily cone beam CT images each were included in the evaluation of the OSG. The evaluation was performed using a total of 18 organs of interest, including 15 organs at risk and 3 targets. Results: Geometric variations of organs of interest during h and n cancer radiotherapy can be represented using the first 3 {approx} 4 eigenvectors. These eigenvectors were variable during treatment, and need to be updated using new daily images obtained during the treatment course. The OSG generates random samples of organs of interest from the estimated organ variation PDF of the individual. The accuracy of the estimated PDF can be improved recursively using extra daily image feedback during the treatment course. The average deviations in the estimation of the mean and standard deviation of the organ variation PDF for h

  17. Hybrid Ant Bee Algorithm for Fuzzy Expert System Based Sample Classification.

    Science.gov (United States)

    GaneshKumar, Pugalendhi; Rani, Chellasamy; Devaraj, Durairaj; Victoire, T Aruldoss Albert

    2014-01-01

    Accuracy maximization and complexity minimization are the two main goals of a fuzzy expert system based microarray data classification. Our previous Genetic Swarm Algorithm (GSA) approach has improved the classification accuracy of the fuzzy expert system at the cost of their interpretability. The if-then rules produced by the GSA are lengthy and complex which is difficult for the physician to understand. To address this interpretability-accuracy tradeoff, the rule set is represented using integer numbers and the task of rule generation is treated as a combinatorial optimization task. Ant colony optimization (ACO) with local and global pheromone updations are applied to find out the fuzzy partition based on the gene expression values for generating simpler rule set. In order to address the formless and continuous expression values of a gene, this paper employs artificial bee colony (ABC) algorithm to evolve the points of membership function. Mutual Information is used for idenfication of informative genes. The performance of the proposed hybrid Ant Bee Algorithm (ABA) is evaluated using six gene expression data sets. From the simulation study, it is found that the proposed approach generated an accurate fuzzy system with highly interpretable and compact rules for all the data sets when compared with other approaches.

  18. Hybrid mathematical and rule-based system for transmission network planning in open access schemes

    Energy Technology Data Exchange (ETDEWEB)

    Kandil, M. S. [Electrical Department, Mansura University, (Egypt); EI-Debeiky, S. M. [Electrical Department, Ain Shams University, (Egypt); Hasanien, N. E. [Egyptian Electricity Authority, Studies and Researches Department, (Egypt)

    2001-09-01

    The paper presents a planning methodology using an application of a mathematical and a rule-based expert system (ES) to expand the transmission network in open access schemes. In this methodology, the ES suggests a realistic set of generation additions with proper economic signals to the participants, before proceeding with the transmission expansion. A feasible list of transmission alternatives is then assumed to accommodate the proposals for generation. A mathematical method is performed based on marginal cost allocation to optimise the location for the new generation and its transmission expansion scheme simultaneously for each alternative. The optimum alternative, which minimises the overall system's cost function and satisfies the future demand under different operating conditions, is obtained. The ES interacts with the power system planning tools to produce the optimum expansion plan. A practical application is given to demonstrate the effectiveness of the developed prototype system. (Author)

  19. Safety and quality assurance of chemotherapeutic preparations in a hospital production unit: acceptance sampling plan and economic impact.

    Science.gov (United States)

    Paci, A; Borget, I; Mercier, L; Azar, Y; Desmaris, R P; Bourget, P

    2012-06-01

    The opportunity to apply a sampling plan was evaluated. Costs were computed by a microcosting study. In 2003, a sampling plan was defined to reduce the number of chemotherapy quality controls while preserving the same level of quality. Recent qualitative and quantitative changes led us to define a second sampling plan supplemented by an economic evaluation to determine the cost and cost-savings of quality control. The study considers preparation produced during four semesters classified into three groups. The first one includes drugs produced below 200 batches a semester. Group 2, those for which the lot of preparation lots would have been rejected twice among these four semesters. Group 3, those would have been accepted (≥3 'acceptable lot'). A single sampling plan by attributes was applied to this group with an acceptance quality level of 1.65% and a lot tolerance percent defective below 5%. A micro-costing study was conducted on quality control, from the sampling to the validation of the results. Among 39 cytotoxic drugs, 11 were sampled which enabled to avoid a mean of 17,512 control assays per year. Each batch of the 28 non-sampled drugs was however analyzed. Costs were estimated at 2.98€ and 5.25€ for control assays depending of the analytical method. The savings from the application of the sampling plans was 153,207€ in 6 years. The sampling plan allowed maintaining constancy in number of controls and the level of quality with significant costsavings, despite a substantial increase in drugs to assay and in the number of preparations produced.

  20. Evaluation of a hybrid sampling train for measuring trace elements and identifying mercury species in combustion flue gas

    Energy Technology Data Exchange (ETDEWEB)

    Miller, S.F.; Wincek, R.T.; Miller, B.G.; Scaroni, A.W.

    1999-07-01

    The Environmental Protection Agency (EPA) initiated an information collection request (ICR) on January 1, 1999 for coal-fired electric utility steam generating units (>25 MW) to document mercury levels in their fuels and emissions. The issuance of an ICR generally precedes the implementation of regulatory action by the EPA. The EPA has designated the Modified Ontario Hydro Method for stack gas sampling to measure total, elemental and oxidized mercury. This recommendation is based on extensive work by the University of North Dakota Energy and Environmental Research Center (UNDEERC) in evaluating a series of methodologies for determining mercury speciation. EPA has also designed the Method 29 sampling train for the sampling and measurement of the other elements identified as HAP's, i.e. As, Be, Cd, Co, Mn, Ni, Pb, Sb, Se, and Hg. Extensive testing has shown that EPA Method 29 may not speciate mercury correctly; however, it may still be used to measure total mercury. Currently there are no emission restrictions on these elements from power plants, however studies are being conducted as to their health risk and environmental impact. The objective of the study is to evaluate a hybrid train consisting of components of both the Modified Ontario Hydro Method and Method 29 sampling trains. Both sampling procedures are very labor intensive and require time to develop sampling expertise. The various sample trains are being tested in a 20 million Btu/hr demonstration boiler and a 2 million Btu/hr research boiler using a variety of fuels and combustion conditions.

  1. Spatially-Optimized Sequential Sampling Plan for Cabbage Aphids Brevicoryne brassicae L. (Hemiptera: Aphididae) in Canola Fields.

    Science.gov (United States)

    Severtson, Dustin; Flower, Ken; Nansen, Christian

    2016-08-01

    The cabbage aphid is a significant pest worldwide in brassica crops, including canola. This pest has shown considerable ability to develop resistance to insecticides, so these should only be applied on a "when and where needed" basis. Thus, optimized sampling plans to accurately assess cabbage aphid densities are critically important to determine the potential need for pesticide applications. In this study, we developed a spatially optimized binomial sequential sampling plan for cabbage aphids in canola fields. Based on five sampled canola fields, sampling plans were developed using 0.1, 0.2, and 0.3 proportions of plants infested as action thresholds. Average sample numbers required to make a decision ranged from 10 to 25 plants. Decreasing acceptable error from 10 to 5% was not considered practically feasible, as it substantially increased the number of samples required to reach a decision. We determined the relationship between the proportions of canola plants infested and cabbage aphid densities per plant, and proposed a spatially optimized sequential sampling plan for cabbage aphids in canola fields, in which spatial features (i.e., edge effects) and optimization of sampling effort (i.e., sequential sampling) are combined. Two forms of stratification were performed to reduce spatial variability caused by edge effects and large field sizes. Spatially optimized sampling, starting at the edge of fields, reduced spatial variability and therefore increased the accuracy of infested plant density estimates. The proposed spatially optimized sampling plan may be used to spatially target insecticide applications, resulting in cost savings, insecticide resistance mitigation, conservation of natural enemies, and reduced environmental impact.

  2. High-Frequency Replanning Under Uncertainty Using Parallel Sampling-Based Motion Planning

    Science.gov (United States)

    Sun, Wen; Patil, Sachin; Alterovitz, Ron

    2015-01-01

    As sampling-based motion planners become faster, they can be re-executed more frequently by a robot during task execution to react to uncertainty in robot motion, obstacle motion, sensing noise, and uncertainty in the robot’s kinematic model. We investigate and analyze high-frequency replanning (HFR), where, during each period, fast sampling-based motion planners are executed in parallel as the robot simultaneously executes the first action of the best motion plan from the previous period. We consider discrete-time systems with stochastic nonlinear (but linearizable) dynamics and observation models with noise drawn from zero mean Gaussian distributions. The objective is to maximize the probability of success (i.e., avoid collision with obstacles and reach the goal) or to minimize path length subject to a lower bound on the probability of success. We show that, as parallel computation power increases, HFR offers asymptotic optimality for these objectives during each period for goal-oriented problems. We then demonstrate the effectiveness of HFR for holonomic and nonholonomic robots including car-like vehicles and steerable medical needles. PMID:26279645

  3. Development of an Integrated GIS and Land Use Planning Course: Impacts of Hybrid Instructional Methods

    Science.gov (United States)

    Kamruzzaman, M.

    2014-01-01

    This study reports an action research undertaken at Queensland University of Technology. It evaluates the effectiveness of the integration of geographic information systems (GIS) within the substantive domains of an existing land use planning course in 2011. Using student performance, learning experience survey, and questionnaire survey data, it…

  4. Dosimetric and geometric evaluation of a hybrid strategy of offline adaptive planning and online image guidance for prostate cancer radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Liu Han; Wu Qiuwen, E-mail: Qiuwen.Wu@Duke.edu [Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710 (United States)

    2011-08-07

    For prostate cancer patients, online image-guided (IG) radiotherapy has been widely used in clinic to correct the translational inter-fractional motion at each treatment fraction. For uncertainties that cannot be corrected online, such as rotation and deformation of the target volume, margins are still required to be added to the clinical target volume (CTV) for the treatment planning. Offline adaptive radiotherapy has been implemented to optimize the treatment for each individual patient based on the measurements at early stages of treatment process. It has been shown that offline adaptive radiotherapy can effectively reduce the required margin. Recently a hybrid strategy of offline adaptive replanning and online IG was proposed and the geometric evaluation was performed. It was found that the planning margins can further be reduced by 1-2 mm compared to online IG only strategy. The purpose of this study was to investigate the dosimetric benefits of such a hybrid strategy on the target and organs at risk. A total of 420 repeated helical computed tomography scans from 28 patients were included in the study. Both low-risk patients (LRP, CTV = prostate) and intermediate-risk patients (IRP, CTV = prostate + seminal vesicles, SV) were included in the simulation. Two registration methods, based on center-of-mass shift of prostate only and prostate plus SV, were performed for IRP. The intensity-modulated radiotherapy was used in the simulation. Criteria on both cumulative and fractional doses were evaluated. Furthermore, the geometric evaluation was extended to investigate the optimal number of fractions necessary to construct the internal target volume (ITV) for the hybrid strategy. The dosimetric margin improvement was smaller than its geometric counterpart and was in the range of 0-1 mm. The optimal number of fractions necessary for the ITV construction is 2 for LRPs and 3-4 for IRPs in a hypofractionation protocol. A new cumulative index of target volume was proposed

  5. Dosimetric and geometric evaluation of a hybrid strategy of offline adaptive planning and online image guidance for prostate cancer radiotherapy

    Science.gov (United States)

    Liu, Han; Wu, Qiuwen

    2011-08-01

    For prostate cancer patients, online image-guided (IG) radiotherapy has been widely used in clinic to correct the translational inter-fractional motion at each treatment fraction. For uncertainties that cannot be corrected online, such as rotation and deformation of the target volume, margins are still required to be added to the clinical target volume (CTV) for the treatment planning. Offline adaptive radiotherapy has been implemented to optimize the treatment for each individual patient based on the measurements at early stages of treatment process. It has been shown that offline adaptive radiotherapy can effectively reduce the required margin. Recently a hybrid strategy of offline adaptive replanning and online IG was proposed and the geometric evaluation was performed. It was found that the planning margins can further be reduced by 1-2 mm compared to online IG only strategy. The purpose of this study was to investigate the dosimetric benefits of such a hybrid strategy on the target and organs at risk. A total of 420 repeated helical computed tomography scans from 28 patients were included in the study. Both low-risk patients (LRP, CTV = prostate) and intermediate-risk patients (IRP, CTV = prostate + seminal vesicles, SV) were included in the simulation. Two registration methods, based on center-of-mass shift of prostate only and prostate plus SV, were performed for IRP. The intensity-modulated radiotherapy was used in the simulation. Criteria on both cumulative and fractional doses were evaluated. Furthermore, the geometric evaluation was extended to investigate the optimal number of fractions necessary to construct the internal target volume (ITV) for the hybrid strategy. The dosimetric margin improvement was smaller than its geometric counterpart and was in the range of 0-1 mm. The optimal number of fractions necessary for the ITV construction is 2 for LRPs and 3-4 for IRPs in a hypofractionation protocol. A new cumulative index of target volume was proposed

  6. Sampling and analysis plan for Mount Plant D & D soils packages, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-02-01

    There are currently 682 containers of soils in storage at Mound Plant, generated between April 1 and October 31, 1990 as a result of excavation of soils containing plutonium-238 at two ongoing Decontamination and Decommissioning (D&D) Program sites. These areas are known as Area 14, the waste transfer system (WTS) hillside, and Area 17, the Special Metallurgical (SM) Building area. The soils from these areas are part of Mound Plant waste stream number AMDM-000000010, Contaminated Soil, and are proposed for shipment to the Nevada Test Site (NTS) for disposal as low-level radioactive waste. The sealed waste packages, constructed of either wood or metal, are currently being stored in Building 31 and at other locations throughout the Mound facility. At a meeting in Las Vegas, Nevada on October, 26, 1990, DOE Nevada Operations Office (DOE-NV) and NTS representatives requested that the Mound Plant D&D soils proposed for shipment to NTS be sampled for Toxicity Characteristic Leaching Procedure (TCLP) constituents. On December 14, 1990, DOE-NV also requested that additional analyses be performed on the soils from one of the soils boxes for polychlorinated biphenyls (PCBs), particle size distribution, and free liquids. The purpose of this plan is to document the proposed sampling and analyses of the packages of D&D soils produced prior to October 31, 1990. In order to provide a thorough description of the soils excavated from the WTS and SM areas, sections 1.1 and 1.2 provide historical Information concerning the D&D soils, including waste stream evaluations and past sampling data.

  7. Hybrid plan verification for intensity-modulated radiation therapy (IMRT) using the 2D ionization chamber array I'mRT MatriXX--a feasibility study.

    Science.gov (United States)

    Dobler, Barbara; Streck, Natalia; Klein, Elisabeth; Loeschel, Rainer; Haertl, Petra; Koelbl, Oliver

    2010-01-21

    The 2D ionization chamber array I'mRT MatriXX (IBA, Schwarzenbruck, Germany) has been developed for absolute 2D dosimetry and verification of intensity-modulated radiation therapy (IMRT) for perpendicular beam incidence. The aim of this study is to evaluate the applicability of I'mRT MatriXX for oblique beam incidence and hybrid plan verification of IMRT with original gantry angles. For the assessment of angular dependence, open fields with gantry angles in steps of 10 degrees were calculated on a CT scan of I'mRT MatriXX. For hybrid plan verification, 17 clinical IMRT plans and one rotational plan were used. Calculations were performed with pencil beam (PB), collapsed cone (CC) and Monte Carlo (MC) methods, which had been previously validated. Measurements were conducted on an Elekta SynergyS linear accelerator. To assess the potential and limitations of the system, gamma evaluation was performed with different dose tolerances and distances to agreement. Hybrid plan verification passed the gamma test with 4% dose tolerance and 3 mm distance to agreement in all cases, in 82-88% of the cases for tolerances of 3%/3 mm, and in 59-76% of the cases if 3%/2 mm were used. Separate evaluation of the low dose and high dose regions showed that I'mRT MatriXX can be used for hybrid plan verification of IMRT plans within 3% dose tolerance and 3 mm distance to agreement with a relaxed dose tolerance of 4% in the low dose region outside the multileaf collimator (MLC).

  8. Seeps and springs sampling and analysis plan for the environmental monitoring plan for Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This Sampling and Analysis Plan addresses the monitoring, sampling, and analysis activities that will be conducted at seeps and springs and at two french drain outlets in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-land-burial disposal facility for low-level radioactive waste at Oak Ridge National Laboratory, a research facility owned by the US Department of Energy and operated by Martin Marietta Energy Systems, Inc. Initially, sampling will be conducted at as many as 15 locations within WAG 6 (as many as 13 seeps and 2 french drain outlets). After evaluating the results obtained and reviewing the observations made by field personnel during the first round of sampling, several seeps and springs will be chosen as permanent monitoring points, together with the two french drain outlets. Baseline sampling of these points will then be conducted quarterly for 1 year (i.e., four rounds of sampling after the initial round). The samples will be analyzed for various geochemical, organic, inorganic, and radiological parameters. Permanent sampling points having suitable flow rates and conditions may be outfitted with automatic flow-monitoring equipment. The results of the sampling and flow-monitoring efforts will help to quantify flux moving across the ungauged perimeter of the site and will help to identify changes in releases from the contaminant sources.

  9. Hybrid recoil mass analyzer at IUAC – First results using gas-filled mode and future plans

    Indian Academy of Sciences (India)

    N Madhavan; S Nath; T Varughese; J Gehlot; A Jhingan; P Sugathan; A K Sinha; R Singh; K M Varier; M C Radhakrishna; E Prasad; S Kalkal; G Mohanto; J J Das; Rakesh Kumar; R P Singh; S Muralithar; R K Bhowmik; A Roy; Rajesh Kumar; S K Suman; A Mandal; T S Datta; J Chacko; A Choudhury; U G Naik; A J Malyadri; M Archunan; J Zacharias; S Rao; Mukesh Kumar; P Barua; E T Subramanian; K Rani; B P Ajith Kumar; K S Golda

    2010-08-01

    Hybrid recoil mass analyzer (HYRA) is a unique, dual-mode spectrometer designed to carry out nuclear reaction and structure studies in heavy and medium-mass nuclei using gas-filled and vacuum modes, respectively and has the potential to address newer domains in nuclear physics accessible using high energy, heavy-ion beams from superconducting LINAC accelerator (being commissioned) and ECR-based high current injector system (planned) at IUAC. The first stage of HYRA is operational and initial experiments have been carried out using gas-filled mode for the detection of heavy evaporation residues and heavy quasielastic recoils in the direction of primary beam. Excellent primary beam rejection and transmission efficiency (comparable with other gas-filled separators) have been achieved using a smaller focal plane detection system. There are plans to couple HYRA to other detector arrays such as Indian national gamma array (INGA) and 4 spin spectrometer for ER tagged spectroscopic/spin distribution studies and for focal plane decay measurements.

  10. Flexible Transmission Network Expansion Planning Considering Uncertain Renewable Generation and Load Demand Based on Hybrid Clustering Analysis

    Directory of Open Access Journals (Sweden)

    Yun-Hao Li

    2015-12-01

    Full Text Available This paper presents a flexible transmission network expansion planning (TNEP approach considering uncertainty. A novel hybrid clustering technique, which integrates the graph partitioning method and rough fuzzy clustering, is proposed to cope with uncertain renewable generation and load demand. The proposed clustering method is capable of recognizing the actual cluster distribution of complex datasets and providing high-quality clustering results. By clustering the hourly data for renewable generation and load demand, a multi-scenario model is proposed to consider the corresponding uncertainties in TNEP. Furthermore, due to the peak distribution characteristics of renewable generation and heavy investment in transmission, the traditional TNEP, which caters to rated renewable power output, is usually uneconomic. To improve the economic efficiency, the multi-objective optimization is incorporated into the multi-scenario TNEP model, while the curtailment of renewable generation is considered as one of the optimization objectives. The solution framework applies a modified NSGA-II algorithm to obtain a set of Pareto optimal planning schemes with different levels of investment costs and renewable generation curtailments. Numerical results on the IEEE RTS-24 system demonstrated the robustness and effectiveness of the proposed approach.

  11. Mycobacterium tuberculosis complex detected by modified fluorescent in situ hybridization in lymph nodes of clinical samples.

    Science.gov (United States)

    Rodriguez-Nuñez, Juan; Avelar, Francisco J; Marquez, Francisco; Rivas-Santiago, Bruno; Quiñones, Cesar; Guerrero-Barrera, Alma L

    2012-01-12

    Lymph node tuberculosis (TB) is the leading cause of extrapulmonary tuberculosis and is the most frequently identified type in Aguascalientes, Mexico. Conventional diagnosis has serious limitations for rapid detection of extrapulmonary tuberculosis in clinical samples. Here PCR and modified FISH have been tested as complementary diagnosis methods for extrapulmonary tuberculosis. The specific insertion sequence IS6110 for Mycobacterium tuberculosis complex was used to perform PCR and build DNA and PNA FISH probes (20bp). PCR and modified DNA and PNA FISH assays were performed to evaluate 41 lymph node paraffin-embedded tissue samples, in comparison with the histopathology diagnosis, which was considered the gold standard (22 positive and 19 negative). In comparison with histopathology diagnosis PCR showed 62.5 % sensitivity and 77.8 % specificity (χ(2) = 4.583 p 0.05). Ziehl Neelsen stain was positive in only four cases of 22 lymph node samples positive to histopathology.  In contrast, PCR and modified DNA FISH were positive in 20 cases of the same group. The negative cases were coincident in all tests. PCR and DNA FISH showed a significant increase in the number of cases detected and also showed higher sensitivity and specificity compared with data reported by traditional methodology. In developing countries, these techniques could help to complement the early diagnosis and timely treatment of extrapulmonary tuberculosis.

  12. Optimal planning of electric vehicle charging station at the distribution system using hybrid optimization algorithm

    DEFF Research Database (Denmark)

    Awasthi, Abhishek; Venkitusamy, Karthikeyan; Padmanaban, Sanjeevikumar

    2017-01-01

    , a hybrid algorithm based on genetic algorithm and improved version of conventional particle swarm optimization is utilized for finding optimal placement of charging station in the Allahabad distribution system. The particle swarm optimization algorithm re-optimizes the received sub-optimal solution (site...... and the size of the station) which leads to an improvement in the algorithm functionality and enhances quality of solution. The genetic algorithm and improved version of conventional particle swarm optimization algorithm will also be compared with a conventional genetic algorithm and particle swarm...... optimization. Through simulation studies on a real time system of Allahabad city, the superior performance of the aforementioned technique with respect to genetic algorithm and particle swarm optimization in terms of improvement in voltage profile and quality....

  13. Sampling and Analysis Plan for Verification Sampling of LANL-Derived Residual Radionuclides in Soils within Tract A-18-2 for Land Conveyance

    Energy Technology Data Exchange (ETDEWEB)

    Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-30

    Public Law 105-119 directs the U.S. Department of Energy (DOE) to convey or transfer parcels of land to the Incorporated County of Los Alamos or their designees and to the Department of Interior, Bureau of Indian Affairs, in trust for the Pueblo de San Ildefonso. Los Alamos National Security is tasked to support DOE in conveyance and/or transfer of identified land parcels no later than September 2022. Under DOE Order 458.1, Radiation Protection of the Public and the Environment (O458.1, 2013) and Los Alamos National Laboratory (LANL or the Laboratory) implementing Policy 412 (P412, 2014), real property with the potential to contain residual radioactive material must meet the criteria for clearance and release to the public. This Sampling and Analysis Plan (SAP) is a second investigation of Tract A-18-2 for the purpose of verifying the previous sampling results (LANL 2017). This sample plan requires 18 projectspecific soil samples for use in radiological clearance decisions consistent with LANL Procedure ENV-ES-TP-238 (2015a) and guidance in the Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM, 2000). The sampling work will be conducted by LANL, and samples will be evaluated by a LANL-contracted independent lab. However, there will be federal review (verification) of all steps of the sampling process.

  14. Locating hybrid individuals in the red wolf (Canis rufus) experimental population area using a spatially targeted sampling strategy and faecal DNA genotyping.

    Science.gov (United States)

    Adams, Jennifer R; Lucash, Chris; Schutte, Leslie; Waits, Lisette P

    2007-05-01

    Hybridization with coyotes (Canis latrans) continues to threaten the recovery of endangered red wolves (Canis rufus) in North Carolina and requires the development of new strategies to detect and remove coyotes and hybrids. Here, we combine a spatially targeted faecal collection strategy with a previously published reference genotype data filtering method and a genetic test for coyote ancestry to screen portions of the red wolf experimental population area for the presence of nonred wolf canids. We also test the accuracy of our maximum-likelihood assignment test for identifying hybrid individuals using eight microsatellite loci instead of the original 18 loci and compare its performance to the Bayesian approach implemented in newhybrids. We obtained faecal DNA genotypes for 89 samples, 73 of which were matched to 23 known individuals. The performance of two sampling strategies - comprehensive sweep and opportunistic spot-check was evaluated. The opportunistic spot-check sampling strategy required less effort than the comprehensive sweep sampling strategy but identified fewer individuals. Six hybrids or coyotes were detected and five of these individuals were subsequently captured and removed from the population. The accuracy and power of the genetic test for coyote ancestry is decreased when using eight loci; however, nonred wolf canids are identified with high frequency. This combination of molecular and traditional field-based approaches has great potential for addressing the challenge of hybridization in other species and ecosystems.

  15. Sampling and analysis plan for the preoperational environmental survey of the spent nuclear fuel project facilities

    Energy Technology Data Exchange (ETDEWEB)

    MITCHELL, R.M.

    1999-04-01

    This sampling and analysis plan will support the preoperational environmental monitoring for construction, development, and operation of the Spent Nuclear Fuel (SNF) Project facilities, which have been designed for the conditioning and storage of spent nuclear fuels; particularly the fuel elements associated with the operation of N-Reactor. The SNF consists principally of irradiated metallic uranium, and therefore includes plutonium and mixed fission products. The primary effort will consist of removing the SNF from the storage basins in K East and K West Areas, placing in multicanister overpacks, vacuum drying, conditioning, and subsequent dry vault storage in the 200 East Area. The primary purpose and need for this action is to reduce the risks to public health and safety and to the environment. Specifically these include prevention of the release of radioactive materials into the air or to the soil surrounding the K Basins, prevention of the potential migration of radionuclides through the soil column to the nearby Columbia River, reduction of occupational radiation exposure, and elimination of the risks to the public and to workers from the deterioration of SNF in the K Basins.

  16. A hybrid algorithm for reliability analysis combining Kriging and subset simulation importance sampling

    Energy Technology Data Exchange (ETDEWEB)

    Tong, Cao; Sun, Zhili; Zhao, Qianli; Wang, Qibin [Northeastern University, Shenyang (China); Wang, Shuang [Jiangxi University of Science and Technology, Ganzhou (China)

    2015-08-15

    To solve the problem of large computation when failure probability with time-consuming numerical model is calculated, we propose an improved active learning reliability method called AK-SSIS based on AK-IS algorithm. First, an improved iterative stopping criterion in active learning is presented so that iterations decrease dramatically. Second, the proposed method introduces Subset simulation importance sampling (SSIS) into the active learning reliability calculation, and then a learning function suitable for SSIS is proposed. Finally, the efficiency of AK-SSIS is proved by two academic examples from the literature. The results show that AK-SSIS requires fewer calls to the performance function than AK-IS, and the failure probability obtained from AK-SSIS is very robust and accurate. Then this method is applied on a spur gear pair for tooth contact fatigue reliability analysis.

  17. SU-E-P-06: A Novel Hybrid Planning Approach to Allow More Patients Benefited by the Intensity Modulated Proton Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, S [UT MD Anderson Cancer Center, Tianjin Medical University Cancer Instit, Houston, TX (United States); Liao, L [UT MD Anderson Cancer Center, University of Houston, Houston, TX (United States); Li, Y [Varian Medical Systems, Houston, TX (United States); Wang, X; Sahoo, N; Liao, Z; Grosshans, D; Frank, S [MD Anderson Cancer Center, Houston, TX (United States); Li, H [M.D. Anderson Cancer Center, Houston, TX (United States); Zhu, X; Chang, J; Zhang, X [UT MD Anderson Cancer Center, Houston, TX (United States); Gillin, M [MD Anderson Cancer Ctr., Houston, TX (United States); Hojo, Y [UT MD Anderson cancer center, Houston, TX (United States); Sun, J [UT MD Anderson cancer center, Tianjin Medical University Cancer Institute a, Houston, TX (United States)

    2014-06-01

    Purpose: We report a hybrid scattering and scanning beam delivery approach, termed as (HimpsPT), which demonstrated that majority IMPT delivery can be potentially replaced with hybrid IMPT and PSPT delivery with similar or better plan quality. Methods: Three representative clinical cases, including head and neck (HN), skull base chordoma (CNS) and lung cancer, treated in MDACC Proton Therapy Center with IMPT were retrospectively redesigned using HimpsPT. The PSPT plans are designed with the same prescriptions as those of IMPT plans. The whole treatment can be delivered by either alternating or sequential PSPT and IMPT delivery. The dosimetric data and dose distributions of HimpsPT plans are compared with those of IMPT plans. We also performed a worst-case robust analysis for all plans. Results: The target coverages for all cases are comparable. For the HN case, the mean dose of esophagus larynx, left parotid and right submandibular, oral cavity V20, the max dose of cord is 18.0, 36.1, 23.6, 47.2, 0.1, 31.7 Gy in HimpsPT plan, and 25.5, 33.8, 24.9, 49.1, 0.2, 33.8 Gy in IMPT plan. For the lung case, the lung V5, V20, V30, mean lung dose, heart V40, esophagus V70, cord maximum dose are 50.5%, 37.0%, 31.7%, 21.3 Gy, 7.2%, 4.9%, 35.5 Gy in HimpsPT plan, and 55.4%, 36.7%, 30.1%, 21.3 Gy, 7.7%, 8.4%, 36.8Gy in IMPT plans. For the CNS case, brainstem maximum dose is 50.5 Gy in HimpsPT plan and 55.4 Gy in IMPT plan due to sharp penumbra offered by the aperture of the PSPT plan in HimpsPT technique. Conclusion: For majority disease sites, the dosimetric advantage of IMPT technique can be achieved by the hybrid PSPT and IMPT technique, which enables the centers equipped with both scattering and scanning beam facilities to treat more patients which can be benefited by the scanning beam.

  18. Preconcentration of Zn(II) in water samples using a new hybrid SBA-15-based material

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Quintanilla, Damian; Sanchez, Alfredo; Hierro, Isabel del; Fajardo, Mariano [Departamento de Quimica Inorganica y Analitica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipan s/n, 28933 Mostoles, Madrid (Spain); Sierra, Isabel, E-mail: isabel.sierra@urjc.es [Departamento de Quimica Inorganica y Analitica, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipan s/n, 28933 Mostoles, Madrid (Spain)

    2009-07-30

    A SBA-15 mesoporous silica has been chemically modified with 5-mercapto-1-methyltetrazole. The newly synthesized material (MTTZ-SBA-15) has been characterized, by powder X-ray diffraction, N{sub 2} adsorption, FT-IR, {sup 13}C NMR spectroscopy and elemental analysis, and used to preconcentrate Zn(II) in water samples. The effect of some variables on the adsorption capacity has been studied using the column techniques. The adsorption capacity of the prepared material followed the order: Zn >> Cu > Cd >> Mn, and under optimized conditions the maximum adsorption value for Zn(II) was 0.96 {+-} 0.01 mmol/g with the adsorption efficiency of 0.76. In column experiments, adsorption was quantitative for 1000 mL of 7.65 x 10{sup -4} mM of Zn(II) solution and adsorbed ions were eluted out by 5 mL of 1 M HCl (preconcentration factor of 200). Spiked tap water and mineral water were used for the preconcentration and determination of Zn(II) by flame atomic absorption spectrometry (FAAS), and a 102 {+-} 2 and 98 {+-} 3% recoveries were obtained. The LOD and LOQ values of the proposed method were found to be 8.0 x 10{sup -6} and 1.23 x 10{sup -5} mM, respectively. The relative standard deviation for four preconcentration experiments was found to be {<=}4% in all cases.

  19. Optimization of operational planning for wind/hydro hybrid water supply systems

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Filipe; Ramos, Helena M. [Department of Civil Engineering, Instituto Superior Tecnico, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal)

    2009-03-15

    Water supply systems (WSS) frequently present high-energy consumption values, which correspond to the major expenses of these systems. Energy costs are a function of its real consumption and of the variability of the daily energy tariff. This paper presents a model of optimization for the energy efficiency in a water supply system. The system is equipped with a pump station and presents excess of available energy in the gravity branch. First, a water turbine is introduced in the system in order to use this excess of hydraulic available energy. Then, an optimization method to define the pump operation planning along the 24 h of simulation, as well as the analysis of the economic benefits resulting from the profit of wind energy to supply the water pumping, while satisfying the system constraints and population demands, is implemented, in order to minimize the global operational costs. The model, developed in MATLAB, uses linear programming and provides the planning strategy to take in each time step, which will influence the following hours. The simulation period considered is one day, sub-divided in hourly time steps. The rules obtained as output of the optimization procedures are subsequently introduced in a hydraulic simulator (e.g. EPANET), in order to verify the system behaviour along the simulation period. The results are compared with the normal operating mode (i.e. without optimization algorithm) and show that energy cost's savings are achieved dependently of the initial reservoir levels or volume. The insertion of the water turbine also generates significant economical benefits for the water supply system. (author)

  20. Planned Missing Data Designs with Small Sample Sizes: How Small Is Too Small?

    Science.gov (United States)

    Jia, Fan; Moore, E. Whitney G.; Kinai, Richard; Crowe, Kelly S.; Schoemann, Alexander M.; Little, Todd D.

    2014-01-01

    Utilizing planned missing data (PMD) designs (ex. 3-form surveys) enables researchers to ask participants fewer questions during the data collection process. An important question, however, is just how few participants are needed to effectively employ planned missing data designs in research studies. This article explores this question by using…

  1. Innovative solutions: sample financial management business plan: neurosurgical intensive care unit.

    Science.gov (United States)

    Villanueva-Baldonado, Analiza; Barrett-Sheridan, Shirley E

    2010-01-01

    This article describes one institution's intention to implement a financial management business plan for a neurosurgical intensive care unit in a level I trauma center. The financial objective of this proposed business plan includes a service increase in the patient population requiring critical care in a way that will help control costs.

  2. Comprehensive work plan and health and safety plan for the 7500 Area Contamination Site sampling at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Burman, S.N.; Landguth, D.C.; Uziel, M.S.; Hatmaker, T.L.; Tiner, P.F.

    1992-05-01

    As part of the Environmental Restoration Program sponsored by the US Department of Energy's Office of Environmental Restoration and Waste Management, this plan has been developed for the environmental sampling efforts at the 7500 Area Contamination Site, Oak Ridge National Laboratory (ORNL), Oak Ridge, Tennessee. This plan was developed by the Measurement Applications and Development Group (MAD) of the Health and Safety Research Division of ORNL and will be implemented by ORNL/MAD. Major components of the plan include (1) a quality assurance project plan that describes the scope and objectives of ORNL/MAD activities at the 7500 Area Contamination Site, assigns responsibilities, and provides emergency information for contingencies that may arise during field operations; (2) sampling and analysis sections; (3) a site-specific health and safety section that describes general site hazards, hazards associated with specific tasks, personnel protection requirements, and mandatory safety procedures; (4) procedures and requirements for equipment decontamination and responsibilities for generated wastes, waste management, and contamination control; and (5) a discussion of form completion and reporting required to document activities at the 7500 Area Contamination Site.

  3. Comprehensive work plan and health and safety plan for the 7500 Area Contamination Site sampling at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Burman, S.N.; Landguth, D.C.; Uziel, M.S.; Hatmaker, T.L.; Tiner, P.F.

    1992-05-01

    As part of the Environmental Restoration Program sponsored by the US Department of Energy`s Office of Environmental Restoration and Waste Management, this plan has been developed for the environmental sampling efforts at the 7500 Area Contamination Site, Oak Ridge National Laboratory (ORNL), Oak Ridge, Tennessee. This plan was developed by the Measurement Applications and Development Group (MAD) of the Health and Safety Research Division of ORNL and will be implemented by ORNL/MAD. Major components of the plan include (1) a quality assurance project plan that describes the scope and objectives of ORNL/MAD activities at the 7500 Area Contamination Site, assigns responsibilities, and provides emergency information for contingencies that may arise during field operations; (2) sampling and analysis sections; (3) a site-specific health and safety section that describes general site hazards, hazards associated with specific tasks, personnel protection requirements, and mandatory safety procedures; (4) procedures and requirements for equipment decontamination and responsibilities for generated wastes, waste management, and contamination control; and (5) a discussion of form completion and reporting required to document activities at the 7500 Area Contamination Site.

  4. Final Remedial Investigation Sampling Plan Addendum. Milan Army Ammunition Plant Remedial Investigation Southern Study Area (Operable Unit No. 5)

    Science.gov (United States)

    1997-09-01

    planned to address these areas. Other field activities will consist of documenting (mapping) surficial extent of these areas via visual inspection...mapping) surficial extent of these areas via visual inspection & field measurements. All sampling activities will be performed with site clearance

  5. Engineering task plan for the annual revision of the rotary mode core sampling system safety equipment list

    Energy Technology Data Exchange (ETDEWEB)

    BOGER, R.M.

    1999-05-13

    This Engineering Task Plan addresses an effort to provide an update to the RMCS Systems 3 and 4 SEL and DCM in order to incorporate the changes to the authorization basis implemented by HNF-SD-WM-BIO-001, Rev. 0 (Draft), Addendum 5 , Safety Analysis for Rotary Mode Core Sampling. Responsibilities, task description, cost estimate, and schedule are presented.

  6. Sampling

    CERN Document Server

    Thompson, Steven K

    2012-01-01

    Praise for the Second Edition "This book has never had a competitor. It is the only book that takes a broad approach to sampling . . . any good personal statistics library should include a copy of this book." —Technometrics "Well-written . . . an excellent book on an important subject. Highly recommended." —Choice "An ideal reference for scientific researchers and other professionals who use sampling." —Zentralblatt Math Features new developments in the field combined with all aspects of obtaining, interpreting, and using sample data Sampling provides an up-to-date treat

  7. Heart dose reduction in breast cancer treatment with simultaneous integrated boost. Comparison of treatment planning and dosimetry for a novel hybrid technique and 3D-CRT

    Energy Technology Data Exchange (ETDEWEB)

    Joest, Vincent; Kretschmer, Matthias; Sabatino, Marcello; Wuerschmidt, Florian; Dahle, Joerg; Lorenzen, Joern [Radiological Alliance, Hamburg (Germany); Ueberle, Friedrich [University of Applied Sciences, Faculty Life Sciences, Hamburg (Germany)

    2015-09-15

    The present study compares in silico treatment plans of clinically established three-dimensional conformal radiotherapy (3D-CRT) with a hybrid technique consisting of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc radiotherapy (VMAT) during normally fractionated radiation of mammary carcinomas with simultaneous integrated boost on the basis of dose-volume histogram (DVH) parameters. Radiation treatment planning was performed with a hybrid and a 3D-CRT treatment plan for 20 patients. Hybrid plans were implemented with two tangential IMRT fields and a VMAT field in the angular range of the tangents. Verification of the plan was performed with a manufacturer-independent measurement system consisting of a detector array and rotation unit. The mean values of the heart dose for the entire patient collective were 3.6 ± 2.5 Gy for 3D-CRT and 2.9 ± 2.1 Gy for the hybrid technique (p < 0.01). For the left side (n = 10), the mean values for the left anterior descending artery were 21.8 ± 7.4 Gy for 3D-CRT and 17.6 ± 7.4 Gy for the hybrid technique (p < 0.01). The mean values of the ipsilateral lung were 11.9 ± 1.6 Gy for 3D-CRT and 10.5 ± 1.3 Gy for the hybrid technique (p < 0.01). Calculated dose distributions in the hybrid arm were in good accordance with measured dose (on average 95.6 ± 0.5 % for γ < 1 and 3 %/3 mm). The difference of the mean treatment time per fraction was 7 s in favor of 3D-CRT. Compared with the established 3D-CRT technique, the hybrid technique allows for a decrease in dose, particularly of the mean heart and lung dose with comparable target volume acquisition and without disadvantageous low-dose load of contralateral structures. Uncomplicated implementation of the hybrid technique was demonstrated in this context. The hybrid technique combines the advantages of tangential IMRT with the superior sparing of organs at risk by VMAT. (orig.) [German] Die vorliegende Studie vergleicht ''in silico

  8. Comparison and Field Validation of Binomial Sampling Plans for Oligonychus perseae (Acari: Tetranychidae) on Hass Avocado in Southern California.

    Science.gov (United States)

    Lara, Jesus R; Hoddle, Mark S

    2015-08-01

    Oligonychus perseae Tuttle, Baker, & Abatiello is a foliar pest of 'Hass' avocados [Persea americana Miller (Lauraceae)]. The recommended action threshold is 50-100 motile mites per leaf, but this count range and other ecological factors associated with O. perseae infestations limit the application of enumerative sampling plans in the field. Consequently, a comprehensive modeling approach was implemented to compare the practical application of various binomial sampling models for decision-making of O. perseae in California. An initial set of sequential binomial sampling models were developed using three mean-proportion modeling techniques (i.e., Taylor's power law, maximum likelihood, and an empirical model) in combination with two-leaf infestation tally thresholds of either one or two mites. Model performance was evaluated using a robust mite count database consisting of >20,000 Hass avocado leaves infested with varying densities of O. perseae and collected from multiple locations. Operating characteristic and average sample number results for sequential binomial models were used as the basis to develop and validate a standardized fixed-size binomial sampling model with guidelines on sample tree and leaf selection within blocks of avocado trees. This final validated model requires a leaf sampling cost of 30 leaves and takes into account the spatial dynamics of O. perseae to make reliable mite density classifications for a 50-mite action threshold. Recommendations for implementing this fixed-size binomial sampling plan to assess densities of O. perseae in commercial California avocado orchards are discussed.

  9. Engineering task plan for rotary mode core sample truck calibration procedure support engineering

    Energy Technology Data Exchange (ETDEWEB)

    BOGER, R.M.

    1999-06-04

    This Engineering Task Plan defines the tasks associated with providing an overview, with respect to the Authorization Basis and PHMC procedures, as applicable, of the calibration documentation for operational equipment for which Characterization Engineering has calibration responsibility.

  10. A Fixed-Precision Sequential Sampling Plan for the Potato Tuberworm Moth, Phthorimaea operculella Zeller (Lepidoptera: Gelechidae), on Potato Cultivars.

    Science.gov (United States)

    Shahbi, M; Rajabpour, A

    2017-02-15

    Phthorimaea operculella Zeller is an important pest of potato in Iran. Spatial distribution and fixed-precision sequential sampling for population estimation of the pest on two potato cultivars, Arinda(®) and Sante(®), were studied in two separate potato fields during two growing seasons (2013-2014 and 2014-2015). Spatial distribution was investigated by Taylor's power law and Iwao's patchiness. Results showed that the spatial distribution of eggs and larvae was random. In contrast to Iwao's patchiness, Taylor's power law provided a highly significant relationship between variance and mean density. Therefore, fixed-precision sequential sampling plan was developed by Green's model at two precision levels of 0.25 and 0.1. The optimum sample size on Arinda(®) and Sante(®) cultivars at precision level of 0.25 ranged from 151 to 813 and 149 to 802 leaves, respectively. At 0.1 precision level, the sample sizes varied from 5083 to 1054 and 5100 to 1050 leaves for Arinda(®) and Sante(®) cultivars, respectively. Therefore, the optimum sample sizes for the cultivars, with different resistance levels, were not significantly different. According to the calculated stop lines, the sampling must be continued until cumulative number of eggs + larvae reached to 15-16 or 96-101 individuals at precision levels of 0.25 or 0.1, respectively. The performance of the sampling plan was validated by resampling analysis using resampling for validation of sampling plans software. The sampling plant provided in this study can be used to obtain a rapid estimate of the pest density with minimal effort.

  11. Sampling and analysis plan for sludge located on the floor and in the pits of the 105-K basins

    Energy Technology Data Exchange (ETDEWEB)

    BAKER, R.B.

    1998-11-20

    This Sampling and Analysis Plan (SAP) provides direction for the sampling of the sludge found on the floor and in the remote pits of the 105-K Basins to provide: (1) basic data for the sludges that have not been characterized to-date and (2) representative Sludge material for process tests to be made by the SNF Project/K Basins sludge treatment process subproject. The sampling equipment developed will remove representative samples of the radioactive sludge from underwater at the K Basins, depositing them in shielded containers for transport to the Hanford Site laboratories. Included in the present document is the basic background logic for selection of the samples to meet the requirements established in the Data Quality Objectives (DQO), HNF-2033, for this sampling activity. The present document also includes the laboratory analyses, methods, procedures, and reporting that will be required to meet the DQO.

  12. Visual Sample Plan (VSP) Statistical Software as Related to the CTBTO’s On-Site Inspection Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Pulsipher, Trenton C.; Walsh, Stephen J.; Pulsipher, Brent A.; Milbrath, Brian D.

    2010-09-01

    In the event of a potential nuclear weapons test the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) is commissioned to conduct an on-site investigation (OSI) of the suspected test site in an effort to find confirmatory evidence of the nuclear test. The OSI activities include collecting air, surface soil, and underground samples to search for indications of a nuclear weapons test - these indicators include radionuclides and radioactive isotopes Ar and Xe. This report investigates the capability of the Visual Sample Plan (VSP) software to contribute to the sampling activities of the CTBTO during an OSI. VSP is a statistical sampling design software, constructed under data quality objectives, which has been adapted for environmental remediation and contamination detection problems for the EPA, US Army, DoD and DHS among others. This report provides discussion of a number of VSP sample designs, which may be pertinent to the work undertaken during an OSI. Examples and descriptions of such designs include hot spot sampling, combined random and judgment sampling, multiple increment sampling, radiological transect surveying, and a brief description of other potentially applicable sampling methods. Further, this work highlights a potential need for the use of statistically based sample designs in OSI activities. The use of such designs may enable canvassing a sample area without full sampling, provide a measure of confidence that radionuclides are not present, and allow investigators to refocus resources in other areas of concern.

  13. Theoretical Antecedents of Standing at Work: An Experience Sampling Approach Using the Theory of Planned Behavior

    Directory of Open Access Journals (Sweden)

    M. Renée Umstattd Meyer

    2016-09-01

    Full Text Available Time spent sitting has been associated with an increased risk of diabetes, cancer, obesity, and mental health impairments. However, 75% of Americans spend most of their days sitting, with work-sitting accounting for 63% of total daily sitting time. Little research examining theory-based antecedents of standing or sitting has been conducted. This lack of solid groundwork makes it difficult to design effective intervention strategies to decrease sitting behaviors. Using the Theory of Planned Behavior (TPB as our theoretical lens to better understand factors related with beneficial standing behaviors already being practiced, we examined relationships between TPB constructs and time spent standing at work among “positive deviants” (those successful in behavior change. Experience sampling methodology (ESM, 4 times a day (midmorning, before lunch, afternoon, and before leaving work for 5 consecutive workdays (Monday to Friday, was used to assess employees’ standing time. TPB scales assessing attitude (α = 0.81–0.84, norms (α = 0.83, perceived behavioral control (α = 0.77, and intention (α = 0.78 were developed using recommended methods and collected once on the Friday before the ESM surveys started. ESM data are hierarchically nested, therefore we tested our hypotheses using multilevel structural equation modeling with Mplus. Hourly full-time university employees (n = 50; 70.6% female, 84.3% white, mean age = 44 (SD = 11, 88.2%in full-time staff positions with sedentary occupation types (time at desk while working ≥6 hours/day participated. A total of 871 daily surveys were completed. Only perceived behavioral control (β = 0.45, p < 0.05 was related with work-standing at the event-level (model fit: just fit; mediation through intention was not supported. This is the first study to examine theoretical antecedents of real-time work-standing in a naturalistic field setting among positive deviants. These relationships should be further

  14. Fixed-precision sequential sampling plans for estimating alfalfa caterpillar, Colias lesbia, egg density in alfalfa, Medicago sativa, fields in Córdoba, Argentina.

    Science.gov (United States)

    Serra, Gerardo V; Porta, Norma C La; Avalos, Susana; Mazzuferi, Vilma

    2013-01-01

    The alfalfa caterpillar, Colias lesbia (Fabricius) (Lepidoptera: Pieridae), is a major pest of alfalfa, Medicago sativa L. (Fabales: Fabaceae), crops in Argentina. Its management is based mainly on chemical control of larvae whenever the larvae exceed the action threshold. To develop and validate fixed-precision sequential sampling plans, an intensive sampling programme for C. lesbia eggs was carried out in two alfalfa plots located in the Province of Córdoba, Argentina, from 1999 to 2002. Using Resampling for Validation of Sampling Plans software, 12 additional independent data sets were used to validate the sequential sampling plan with precision levels of 0.10 and 0.25 (SE/mean), respectively. For a range of mean densities of 0.10 to 8.35 eggs/sample, an average sample size of only 27 and 26 sample units was required to achieve a desired precision level of 0.25 for the sampling plans of Green and Kuno, respectively. As the precision level was increased to 0.10, average sample size increased to 161 and 157 sample units for the sampling plans of Green and Kuno, respectively. We recommend using Green's sequential sampling plan because it is less sensitive to changes in egg density. These sampling plans are a valuable tool for researchers to study population dynamics and to evaluate integrated pest management strategies.

  15. Diagnosis of canine visceral leishmaniasis with radiolabelled probes: comparison of the kDNA PCR-hybridization with three molecular methods in different clinical samples

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Aline Leandra C.; Ferreira, Sidney A.; Carregal, Virginia M.; Andrade, Antero Silva R., E-mail: antero@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Lab. de Radiobiologia; Melo, Maria N., E-mail: melo@icb.ufmg.br [Departamento de Parasitologia. Instituto de Ciencias Biologicas. Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil)

    2011-07-01

    Leishmania (Leishmania) chagasi is responsible for visceral leishmaniasis (VL) in Brazil and the dog is the main domestic reservoir. Disease control is based on the elimination of infected animals and the use of a sensitive and specific diagnostic test is necessary. The Brazilian VL control program emphasizes serologic surveys, mainly using the enzyme-linked immunosorbent assay (ELISA) and the immunofluorescence antibody test (IFAT), followed by the elimination of the seropositive dogs. However, these techniques present limitations in terms of sensitivity and specificity. The Polymerase Chain Reaction (PCR) associated to hybridization with DNA probes labeled with {sup 32}P has been recognized as a valuable tool for Leishmania identification. In this study, the sensitivity of kDNA PCR hybridization method was compared with three other molecular methods: Internal Transcribed Spacer 1 Nested PCR (ITS-1nPCR), Leishmania nested PCR (LnPCR) and Seminested kDNA PCR (kDNA snPCR). The comparison was performed in different clinical specimens: conjunctival swab, skin, blood and bone marrow. A group of thirty symptomatic dogs, positive in the parasitological and serological tests, was used. When. The techniques targeting kDNA mini-circles (kDNA snPCR and KDNA PCR-hybridization) showed the worst result for blood samples. The KDNA-PCR hybridization showed the best sensitivity for conjunctival swab. By comparing the samples on the basis of positivity obtained by the sum of all methods, the blood showed the worst outcome (71/120).The bone marrow showed the highest positivity (106/120), followed by conjunctival swab (100/120) and skin (89/120). Since the bone marrow samples are unsuitable for routine epidemiological surveys, the conjunctival swab was recommended because it allows high sensitivity, especially when associated with kDNA PCR hybridization method, and is a noninvasive sampling method. (author)

  16. Remedial investigation sampling and analysis plan for J-Field, Aberdeen Proving Ground, Maryland: Volume 2, Quality Assurance Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Prasad, S.; Martino, L.; Patton, T.

    1995-03-01

    J-Field encompasses about 460 acres at the southern end of the Gunpowder Neck Peninsula in the Edgewood Area of APG (Figure 2.1). Since World War II, the Edgewood Area of APG has been used to develop, manufacture, test, and destroy chemical agents and munitions. These materials were destroyed at J-Field by open burning and open detonation (OB/OD). For the purposes of this project, J-Field has been divided into eight geographic areas or facilities that are designated as areas of concern (AOCs): the Toxic Burning Pits (TBP), the White Phosphorus Burning Pits (WPP), the Riot Control Burning Pit (RCP), the Robins Point Demolition Ground (RPDG), the Robins Point Tower Site (RPTS), the South Beach Demolition Ground (SBDG), the South Beach Trench (SBT), and the Prototype Building (PB). The scope of this project is to conduct a remedial investigation/feasibility study (RI/FS) and ecological risk assessment to evaluate the impacts of past disposal activities at the J-Field site. Sampling for the RI will be carried out in three stages (I, II, and III) as detailed in the FSP. A phased approach will be used for the J-Field ecological risk assessment (ERA).

  17. Field Sampling Plan for Closure of the Central Facilities Area Sewage Treatment Plant Lagoon 3 and Land Application Area

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Michael George [Idaho National Laboratory

    2016-10-01

    This field sampling plan describes sampling of the soil/liner of Lagoon 3 at the Central Facilities Area Sewage Treatment Plant. The lagoon is to be closed, and samples obtained from the soil/liner will provide information to determine if Lagoon 3 and the land application area can be closed in a manner that renders it safe to human health and the environment. Samples collected under this field sampling plan will be compared to Idaho National Laboratory background soil concentrations. If the concentrations of constituents of concern exceed the background level, they will be compared to Comprehensive Environmental Response, Compensation, and Liability Act preliminary remediation goals and Resource Conservation and Recovery Act levels. If the concentrations of constituents of concern are lower than the background levels, Resource Conservation and Recovery Act levels, or the preliminary remediation goals, then Lagoon 3 and the land application area will be closed. If the Resource Conservation and Recovery Act levels and/or the Comprehensive Environmental Response, Compensation, and Liability Act preliminary remediation goals are exceeded, additional sampling and action may be required.

  18. A Hybrid Fuzzy Inference System Based on Dispersion Model for Quantitative Environmental Health Impact Assessment of Urban Transportation Planning

    Directory of Open Access Journals (Sweden)

    Behnam Tashayo

    2017-01-01

    Full Text Available Characterizing the spatial variation of traffic-related air pollution has been and is a long-standing challenge in quantitative environmental health impact assessment of urban transportation planning. Advanced approaches are required for modeling complex relationships among traffic, air pollution, and adverse health outcomes by considering uncertainties in the available data. A new hybrid fuzzy model is developed and implemented through hierarchical fuzzy inference system (HFIS. This model is integrated with a dispersion model in order to model the effect of transportation system on the PM2.5 concentration. An improved health metric is developed as well based on a HFIS to model the impact of traffic-related PM2.5 on health. Two solutions are applied to improve the performance of both the models: the topologies of HFISs are selected according to the problem and used variables, membership functions, and rule set are determined through learning in a simultaneous manner. The capabilities of this proposed approach is examined by assessing the impacts of three traffic scenarios involved in air pollution in the city of Isfahan, Iran, and the model accuracy compared to the results of available models from literature. The advantages here are modeling the spatial variation of PM2.5 with high resolution, appropriate processing requirements, and considering the interaction between emissions and meteorological processes. These models are capable of using the available qualitative and uncertain data. These models are of appropriate accuracy, and can provide better understanding of the phenomena in addition to assess the impact of each parameter for the planners.

  19. Hybrid Powder - Single Crystal X-Ray Diffraction Instrument for Planetary Mineralogical Analysis of Unprepared Samples Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop a planetary exploration XRD/XRF instrument based on a hybrid diffraction approach that complements powder XRD analysis, similar to that of the...

  20. Counting, enumerating and sampling of execution plans in a cost-based query optimizer

    NARCIS (Netherlands)

    F. Waas; C.A. Galindo-Legaria

    1999-01-01

    textabstractTesting an SQL database system by running large sets of deterministic or stochastic SQL statements is common practice in commercial database development. However, code defects often remain undetected as the query optimizer's choice of an execution plan is not only depending on

  1. Counting, Enumerating and Sampling of Execution Plans in a Cost-Based Query Optimizer

    NARCIS (Netherlands)

    F. Waas; C.A. Galindo-Legaria

    2000-01-01

    textabstractTesting an SQL database system by running large sets of deterministic or stochastic SQL statements is common practice in commercial database development. However, code defects often remain undetected as the query optimizer's choice of an execution plan is not only depending on the query

  2. Corganiser: a web-based software tool for planning time-sensitive sampling of whole rounds during scientific drilling

    DEFF Research Database (Denmark)

    Marshall, Ian

    2014-01-01

    Corganiser is a software tool developed to simplify the process of preparing whole-round sampling plans for time-sensitive microbiology and geochemistry sampling during scientific drilling. It was developed during the Integrated Ocean Drilling Program (IODP) Expedition 347, but is designed to work...... with a wide range of core and section configurations and can thus be used in future drilling projects. Corganiser is written in the Python programming language and is implemented both as a graphical web interface and command-line interface. It can be accessed online at http://130.226.247.137/....

  3. Discrete Sampling Test Plan for the 200-BP-5 Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    Sweeney, Mark D.

    2010-02-04

    The Discrete Groundwater Sampling Project is conducted by the Pacific Northwest National Laboratory (PNNL) on behalf of CH2M HILL Plateau Remediation Company. The project is focused on delivering groundwater samples from proscribed horizons within select groundwater wells residing in the 200-BP-5 Operable Unit (200-BP-5 OU) on the Hanford Site. This document provides the scope, schedule, methodology, and other details of the PNNL discrete sampling effort.

  4. 7 CFR 42.111 - Sampling plans for reduced condition of container inspection, Tables III and III-A; and limit...

    Science.gov (United States)

    2010-01-01

    ... Inspection Code Lot size ranges—Number of containers in lot Type of plan Sample size Acceptable quality... 7 Agriculture 2 2010-01-01 2010-01-01 false Sampling plans for reduced condition of container... Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE...

  5. SINGLE SAMPLING PLANS FOR VARIABLES INDEXED BY AQL AND AOQL UNDER EWMA MODEL

    Directory of Open Access Journals (Sweden)

    J. R. Singh

    2012-12-01

    Full Text Available The objective of this paper is to provide expression for evaluating sample size(n,acceptance parameter(k, Average Outgoing Quality(AOQ and Operating Characteristic(OCfunction under Exponentially Weighted Moving Average (EWMA model. The paper provides aninvestigation into the robustness of single sampling procedure indexed by Acceptance QualityLevel(AQL and Average Outgoing Quality Level(AOQL.

  6. Designing a Sample Selection Plan to Improve Generalizations from Two Scale-Up Experiments

    Science.gov (United States)

    Tipton, Elizabeth; Sullivan, Kate; Hedges, Larry; Vaden-Kiernan, Michael; Borman, Geoffrey; Caverly, Sarah

    2011-01-01

    In this paper the authors present a new method for sample selection for scale-up experiments. This method uses propensity score matching methods to create a sample that is similar in composition to a well-defined generalization population. The method they present is flexible and practical in the sense that it identifies units to be targeted for…

  7. Groundwater level monitoring sampling and analysis plan for the environmental monitoring plan at waste area grouping 6, Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This document is the Groundwater Level Monitoring Sampling and Analysis Plan (SAP) for Waste Area Grouping (WAG) 6 at Oak Ridge National Laboratory (ORNL). Note that this document is referred to as a SAP even though no sampling and analysis will be conducted. The term SAP is used for consistency. The procedures described herein are part of the Environmental Monitoring Plan (EMP) for WAG 6, which also includes monitoring tasks for seeps and springs, groundwater quality, surface water, and meteorological parameters. Separate SAPs are being issued concurrently to describe each of these monitoring programs. This SAP has been written for the use of the field personnel responsible for implementation of the EMP, with the intent that the field personnel will be able to take these documents to the field and quickly find the appropriate steps required to complete a specific task. In many cases, Field Operations Procedures (FOPs) will define the steps required for an activity. The FOPs for the EMP are referenced and briefly described in the relevant sections of the SAPs, and are contained within the FOP Manual. Both these documents (the SAP and the FOP Manual) will be available to personnel in the field.

  8. Engineering task plan for upgrades to the leveling jacks on core sample trucks number 3 and 4

    Energy Technology Data Exchange (ETDEWEB)

    KOSTELNIK, A.J.

    1999-02-24

    Characterizing the waste in underground storage tanks at the Hanford Site is accomplished by obtaining a representative core sample for analysis. Core sampling is one of the numerous techniques that have been developed for use given the environmental and field conditions at the Hanford Site. Core sampling is currently accomplished using either Push Mode Core Sample Truck No.1 or; Rotary Mode Core Sample Trucks No.2, 3 or 4. Past analysis (WHC 1994) has indicated that the Core Sample Truck (CST) leveling jacks are structurally inadequate when lateral loads are applied. WHC 1994 identifies many areas where failure could occur. All these failures are based on exceeding the allowable stresses listed in the American Institute of Steel Construction (AISC) code. The mode of failure is for the outrigger attachments to the truck frame to fail resulting in dropping of the CST and possible overturning (Ref. Ziada and Hundal, 1996). Out of level deployment of the truck can exceed the code allowable stresses in the structure. Calculations have been performed to establish limits for maintaining the truck level when lifting. The calculations and the associated limits are included in appendix A. The need for future operations of the CSTS is limited. Sampling is expected to be complete in FY-2001. Since there is limited time at risk for continued use of the CSTS with the leveling controls without correcting the structural problems, there are several design changes that could give incremental improvements to the operational safety of the CSTS with limited impact on available operating time. The improvements focus on making the truck easier to control during lifting and leveling. Not all of the tasks identified in this ETP need to be performed. Each task alone can improve the safety. This engineering task plan is the management plan document for implementing the necessary additional structural analysis. Any additional changes to meet requirements of standing orders shall require a

  9. Sampled-data-based consensus and containment control of multiple harmonic oscillators: A motion-planning approach

    Science.gov (United States)

    Liu, Yongfang; Zhao, Yu; Chen, Guanrong

    2016-11-01

    This paper studies the distributed consensus and containment problems for a group of harmonic oscillators with a directed communication topology. First, for consensus without a leader, a class of distributed consensus protocols is designed by using motion planning and Pontryagin's principle. The proposed protocol only requires relative information measurements at the sampling instants, without requiring information exchange over the sampled interval. By using stability theory and the properties of stochastic matrices, it is proved that the distributed consensus problem can be solved in the motion planning framework. Second, for the case with multiple leaders, a class of distributed containment protocols is developed for followers such that their positions and velocities can ultimately converge to the convex hull formed by those of the leaders. Compared with the existing consensus algorithms, a remarkable advantage of the proposed sampled-data-based protocols is that the sampling periods, communication topologies and control gains are all decoupled and can be separately designed, which relaxes many restrictions in controllers design. Finally, some numerical examples are given to illustrate the effectiveness of the analytical results.

  10. Sampling based motion planning with reachable volumes: Application to manipulators and closed chain systems

    KAUST Repository

    McMahon, Troy

    2014-09-01

    © 2014 IEEE. Reachable volumes are a geometric representation of the regions the joints of a robot can reach. They can be used to generate constraint satisfying samples for problems including complicated linkage robots (e.g. closed chains and graspers). They can also be used to assist robot operators and to help in robot design.We show that reachable volumes have an O(1) complexity in unconstrained problems as well as in many constrained problems. We also show that reachable volumes can be computed in linear time and that reachable volume samples can be generated in linear time in problems without constraints. We experimentally validate reachable volume sampling, both with and without constraints on end effectors and/or internal joints. We show that reachable volume samples are less likely to be invalid due to self-collisions, making reachable volume sampling significantly more efficient for higher dimensional problems. We also show that these samples are easier to connect than others, resulting in better connected roadmaps. We demonstrate that our method can be applied to 262-dof, multi-loop, and tree-like linkages including combinations of planar, prismatic and spherical joints. In contrast, existing methods either cannot be used for these problems or do not produce good quality solutions.

  11. SmartPATH: An Efficient Hybrid ACO-GA Algorithm for Solving the Global Path Planning Problem of Mobile Robots

    Directory of Open Access Journals (Sweden)

    Imen Châari

    2014-07-01

    Full Text Available Path planning is a fundamental optimization problem that is crucial for the navigation of a mobile robot. Among the vast array of optimization approaches, we focus in this paper on Ant Colony Optimization (ACO and Genetic Algorithms (GA for solving the global path planning problem in a static environment, considering their effectiveness in solving such a problem. Our objective is to design an efficient hybrid algorithm that takes profit of the advantages of both ACO and GA approaches for the sake of maximizing the chance to find the optimal path even under real-time constraints. In this paper, we present smartPATH, a new hybrid ACO-GA algorithm that relies on the combination of an improved ACO algorithm (IACO for efficient and fast path selection, and a modified crossover operator to reduce the risk of falling into a local minimum. We demonstrate through extensive simulations that smartPATH outperforms classical ACO (CACO, GA algorithms. It also outperforms the Dijkstra exact method in solving the path planning problem for large graph environments. It improves the solution quality up to 57% in comparison with CACO and reduces the execution time up to 83% as compared to Dijkstra for large and dense graphs. In addition, the experimental results on a real robot shows that smartPATH finds the optimal path with a probability up to 80% with a small gap not exceeding 1m in 98%.

  12. Field Sampling Plan for the Operable Units 6-05 and 10-04 Remedial Action, Phase IV

    Energy Technology Data Exchange (ETDEWEB)

    R. Wells

    2006-11-14

    This Field Sampling Plan outlines the collection and analysis of samples in support of Phase IV of the Waste Area Group 10, Operable Units 6-05 and 10-04 remedial action. Phase IV addresses the remedial actions to areas with the potential for unexploded ordnance at the Idaho National Laboratory Site. These areas include portions of the Naval Proving Ground, the Arco High-Altitude Bombing Range, and the Twin Buttes Bombing Range. The remedial action consists of removal and disposal of ordnance by high-order detonation, followed by sampling to determine the extent, if any, of soil that might have been contaminated by the detonation activities associated with the disposal of ordnance during the Phase IV activities and explosives during the Phase II activities.

  13. Sample Size Planning for the Squared Multiple Correlation Coefficient: Accuracy in Parameter Estimation via Narrow Confidence Intervals.

    Science.gov (United States)

    Kelley, Ken

    2008-01-01

    Methods of sample size planning are developed from the accuracy in parameter approach in the multiple regression context in order to obtain a sufficiently narrow confidence interval for the population squared multiple correlation coefficient when regressors are random. Approximate and exact methods are developed that provide necessary sample size so that the expected width of the confidence interval will be sufficiently narrow. Modifications of these methods are then developed so that necessary sample size will lead to sufficiently narrow confidence intervals with no less than some desired degree of assurance. Computer routines have been developed and are included within the MBESS R package so that the methods discussed in the article can be implemented. The methods and computer routines are demonstrated using an empirical example linking innovation in the health services industry with previous innovation, personality factors, and group climate characteristics.

  14. Household waste behaviours among a community sample in Iran: an application of the theory of planned behaviour.

    Science.gov (United States)

    Pakpour, Amir H; Zeidi, Isa Mohammadi; Emamjomeh, Mohammad Mahdi; Asefzadeh, Saeed; Pearson, Heidi

    2014-06-01

    Understanding the factors influencing recycling behaviour can lead to better and more effective recycling programs in a community. The goal of this study was to examine factors associated with household waste behaviours in the context of the theory of planned behaviour (TPB) among a community sample of Iranians that included data collection at time 1 and at follow-up one year later at time 2. Study participants were sampled from households under the coverage of eight urban health centers in the city of Qazvin. Of 2000 invited households, 1782 agreed to participate in the study. A self-reported questionnaire was used for assessing socio-demographic factors and the TPB constructs (i.e. attitude, subjective norms, perceived behavioural control, and intention). Furthermore, questions regarding moral obligation, self-identity, action planning, and past recycling behaviour were asked, creating an extended TPB. At time 2, participants were asked to complete a follow-up questionnaire on self-reported recycling behaviours. All TPB constructs had positive and significant correlations with each other. Recycling behaviour at time 1 (past behaviour) significantly related to household waste behaviour at time 2. The extended TPB explained 47% of the variance in household waste behaviour at time 2. Attitude, perceived behavioural control, intention, moral obligation, self-identity, action planning, and past recycling behaviour were significant predictors of household waste behaviour at time 2 in all models. The fact that the expanded TPB constructs significantly predicted household waste behaviours holds great promise for developing effective public campaigns and behaviour-changing interventions in a region where overall rates of household waste reduction behaviours are low. Our results indicate that educational materials which target moral obligation and action planning may be particularly effective. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Detection of Lawsonia intracellularis in formalinfixed Porcine Intestinal Tissue Samples: Comparison of Immunofluorescense and In-situ Hybridization, and Evaluation of the Effectf of Controlled Autolysis

    DEFF Research Database (Denmark)

    Jensen, Tim Kåre; Boesen, H. T.; Vigre, Håkan;

    2010-01-01

    Two methods, an immunofluorescence assay (IFA; with a Lawsonia intracellularis-specific monoclonal antibody) and fluorescent in-situ hybridization (FISH; with a specific oligonucleotide probe targeting 16S ribosomal RNA of the bacterium), were compared for their ability to detect L. intracellularis...... (the cause of porcine proliferative enteritis [PE]) in formalin-fixed samples of intestinal tissue. Of 69 intestinal samples with gross lesions of PE, 63 were positive by both FISH and IFA, but six were positive only by IFA. This indicated that the sensitivity of FISH was 91% that of IFA. However, both...

  16. Microbiology of subsurface environments: Deep Probe sampling design and planning workshop

    Energy Technology Data Exchange (ETDEWEB)

    Wobber, F.J.; Zachara, J.M.

    1987-01-01

    This report describes the results of an invited workshop in support of DOE's microbiology research program (Deep Probe). This report summarizes the major recommendations of the workshop, and contains DOE's perspectives on tasks related to the following areas: drilling and coring procedures; tracer technologies and issues of contamination; supplementary geohydrological, sedimentological and geological analysis relevant to analysis of deep microbial habitats; statistical analysis of existing samples; experimental design for future coring; improvements in microbiological sampling, core handling, and acquisition of pore water chemical samples; interlaboratory standardization of microbiological protocols; DOE's strategy for extension of the research to other hydrogeological regimes; and, accelerated information exchange with the scientific community.

  17. 7 CFR 52.38 - Sampling plans and procedures for determining lot compliance.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS... sample size, the lot fails the requirement. (c) If in the conduct of on-line in-plant inspection of a...

  18. USE OF SCALED SEMIVARIOGRAMS IN THE PLANNING SAMPLE OF SOIL CHEMICAL PROPERTIES IN SOUTHERN AMAZONAS, BRAZIL

    Directory of Open Access Journals (Sweden)

    Ivanildo Amorim de Oliveira

    2015-02-01

    Full Text Available The lack of information concerning the variability of soil properties has been a major concern of researchers in the Amazon region. Thus, the aim of this study was to evaluate the spatial variability of soil chemical properties and determine minimal sampling density to characterize the variability of these properties in five environments located in the south of the State of Amazonas, Brazil. The five environments were archaeological dark earth (ADE, forest, pasture land, agroforestry operation, and sugarcane crop. Regular 70 × 70 m mesh grids were set up in these areas, with 64 sample points spaced at 10 m distance. Soil samples were collected at the 0.0-0.1 m depth. The chemical properties of pH in water, OM, P, K, Ca, Mg, H+Al, SB, CEC, and V were determined at these points. Data were analyzed by descriptive and geostatistical analyses. A large part of the data analyzed showed spatial dependence. Chemical properties were best fitted to the spherical model in almost all the environments evaluated, except for the sugarcane field with a better fit to the exponential model. ADE and sugarcane areas had greater heterogeneity of soil chemical properties, showing a greater range and higher sampling density; however, forest and agroforestry areas had less variability of chemical properties.

  19. Sample-Based Motion Planning in High-Dimensional and Differentially-Constrained Systems

    Science.gov (United States)

    2010-02-01

    tasks, such as the piano -mover problem, has been shown to be PSPACE-Hard [Reif, 1979]. Despite this time complexity, sample-based methods have proven...point. See [Berkemeier et al., 1999] for one such technique , and for an overview of related. 23 Alternative approaches such as [Stojic et al., 2000] study...the angular momentum. The technique was extend to 3 DOF by ignoring non-linear terms, and used to control landing in a gymnastic robot using feedback

  20. SAMPLING PLAN FOR ASSESSING BROWN ROT SEVERITY IN PEACHES SUBJECTED TO DIFFERENT PLANT EXTRACTS

    Directory of Open Access Journals (Sweden)

    KELLY PAZOLINI

    2016-01-01

    Full Text Available The identification of brown rot control derivatives has been the focus of intense research owing to the negative effects of the unrelenting usage of fungicides. Brown rot, caused by Monilinia fructicola, is an important post-harvest disease of peaches. The goal of this study was to estimate the optimum sample size of peaches in order to assess the average lesion size and the influence of different plant extracts on the fruits. Three preparation forms (FPE were evaluated, as well as another seven forms of application (FAE of canola and mustard extracts on peaches, with applications of the pathogen’s inoculum. Five fruits were utilized in five repetitions per treatment. Evaluation involved measurement of the fruits’ lesioned areas. The necessary sampling size was determined for estimation of the averages for each treatment and experiment. For measurement of the lesion size, 99 fruits in FPE and 23 fruits in FAE were sufficient for estimating the average with an estimation error of 10%. Based on the same estimation error, the sampling size is contingent on the extracts (canola, and mustard, batches of fruits, forms of extraction, and extract application on the fruits.

  1. Model and hybrid algorithm for hot rolling lot planning%热轧批量计划模型及其混合求解算法

    Institute of Scientific and Technical Information of China (English)

    屠乃威; 黄辉; 罗小川; 柴天佑

    2011-01-01

    分析了热轧批量计划编制问题,建立了基于奖金收集车辆路径问题的计划数不确定的热轧批量计划模型.模型中考虑了热轧生产的多种工艺约束和生产目标.针对该模型提出了一种基于模拟退火算法和蚁群算法的混合算法,混合算法中利用模拟退火算法得到热轧批量计划的一个初始解来生成蚁群算法中的初始信息素分布,利用蚁群算法寻找全局最优解.在蚁群算法中又嵌入了模拟退火算法进行局部搜索,避免蚁群算法陷入局部最优.实验结果表明所提出的模型和算法是有效的.%Hot rolling Iot planning is analyzed and a prize collecting vehicle routing problem(PCVRP) model with uncertain rolling planning numbers for hot rolling lot planning is proposed. The model considers a lot of production process constraints and production targets. A hybrid algorithm based on simulated annealing(SA)and ant colony optimization(ACO) is proposed for solving the model. In the hybrid algorithm, simulated annealing is used to search the initial solution of hot rolling lot planning to form the initial information pheromone, ant colony optimization is used to search the global optimal solution. Simulated annealing employs certain probability to avoid becoming trapped in a local optimum in ant colony optimization. The experimental results show that the model and the hybrid algorithm are effective for hot rolling lot planning.

  2. Groundwater quality sampling and analysis plan for environmental monitoring in Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    This Sampling and Analysis Plan addresses groundwater quality sampling and analysis activities that will be conducted in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-burial land disposal facility for low-level radioactive waste at the Oak Ridge National Laboratory, a research facility owned by the US Department of energy and managed by martin Marietta Energy Systems, Inc. (Energy Systems). Groundwater sampling will be conducted by Energy Systems at 45 wells within WAG 6. The samples will be analyzed for various organic, inorganic, and radiological parameters. The information derived from the groundwater quality monitoring, sampling, and analysis will aid in evaluating relative risk associated with contaminants migrating off-WAG, and also will fulfill Resource Conservation and Recovery Act (RCRA) interim permit monitoring requirements. The sampling steps described in this plan are consistent with the steps that have previously been followed by Energy Systems when conducting RCRA sampling.

  3. Groundwater Quality Sampling and Analysis Plan for Environmental Monitoring Waste Area Grouping 6 at Oak Ridge National Laboratory. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This Sampling and Analysis Plan addresses groundwater quality sampling and analysis activities that will be conducted in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-burial land disposal facility for low-level radioactive waste at the Oak Ridge National Laboratory, a research facility owned by the US Department of Energy and managed by Martin Marietta Energy Systems, Inc. (Energy Systems). Groundwater sampling will be conducted by Energy Systems at 45 wells within WAG 6. The samples will be analyzed for various organic, inorganic, and radiological parameters. The information derived from the groundwater quality monitoring, sampling, and analysis will aid in evaluating relative risk associated with contaminants migrating off-WAG, and also will fulfill Resource Conservation and Recovery Act (RCRA) interim permit monitoring requirements. The sampling steps described in this plan are consistent with the steps that have previously been followed by Energy Systems when conducting RCRA sampling.

  4. Y-12 Groundwater Protection Program Groundwater And Surface Water Sampling And Analysis Plan For Calendar Year 2008

    Energy Technology Data Exchange (ETDEWEB)

    Elvado Environmental LLC

    2007-09-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2008 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2008 will be in accordance with DOE Order 540.1 requirements and the following goals: (1) to protect the worker, the public, and the environment; (2) to maintain surveillance of existing and potential groundwater contamination sources; (3) to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are most likely to migrate beyond the Oak Ridge Reservation property line; (4) to identify and characterize long-term trends in groundwater quality at Y-12; and (5) to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2008 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation (Figure A.1). Modifications to the CY 2008 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells or may add or remove wells from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and

  5. Y-12 Groundwater Protection Program Groundwater and Surface Water Sampling and Analysis Plan For Calendar Year 2009

    Energy Technology Data Exchange (ETDEWEB)

    Elvado Environmental LLC

    2008-12-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2009 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2009 will be in accordance with DOE Order 540.1 requirements and the following goals: (1) to protect the worker, the public, and the environment; (2) to maintain surveillance of existing and potential groundwater contamination sources; (3) to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are most likely to migrate beyond the Oak Ridge Reservation property line; (4) to identify and characterize long-term trends in groundwater quality at Y-12; and (5) to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2009 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation. Modifications to the CY 2009 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells or may add or remove wells from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and analysis plan

  6. Y-12 Plant Groundwater Protection Program Groundwater and Surface Water sampling and Analysis Plan for Calendar Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    None

    1999-09-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2000 at the U.S. Department of Energy (DOE) Y-12 Plant that will be managed by tie Y-12 Plant Groundwater Protection Program (GWPP). Groundwater and surface water monitoring during CY 2000 will be performed in three hydrogeologic regimes at the Y-12 Plant: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of the Y-12 Plant (Figure 1). Groundwater and surface water monitoring performed under the auspices of the Y-12 Plant GWPP during CY 2000 will comply with: Tennessee Department of Environment and Conservation regulations governing detection monitoring at nonhazardous Solid Waste Disposal Facilities (SWDF); and DOE Order 5400.1 surveillance monitoring and exit pathway/perimeter monitoring. Some of the data collected for these monitoring drivers also will be used to meet monitoring requirements of the Integrated Water Quality Program, which is managed by Bechtel Jacobs Company LLC. Data from five wells that are monitored for SWDF purposes in the Chestnut Ridge Regime will be used to comply with requirements specified in the Resource Conservation and Recovery Act post closure permit regarding corrective action monitoring. Modifications to the CY 2000 monitoring program may be necessary during implementation. Changes in regulatory or programmatic requirements may alter the analytes specified for selected monitoring wells, or wells could be added or removed from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 Plant GWPP manager and documented as addenda to this sampling and analysis plan.

  7. Final work plan : targeted groundwater sampling and monitoring well installation for potential site reclassification at Barnes, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.

    2006-07-11

    This ''Work Plan'' outlines the scope of work for a targeted groundwater sampling investigation and monitoring well installation at Barnes, Kansas. This activity is being conducted at the request of the Kansas Department of Health and Environment (KDHE), in accordance with the intergovernmental agreement between the KDHE and the Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA). Data resulting from the proposed work will be used to determine the hydraulic gradient near the former CCC/USDA facility, delineate the downgradient carbon tetrachloride plume, and determine additional monitoring requirements at Barnes. The overall goal is to establish criteria for monitoring leading to potential site reclassification. The proposed work will be performed on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by the University of Chicago for the U.S. Department of Energy (DOE). The Farm Service Agency of the USDA has entered into an interagency agreement with DOE, under which Argonne provides technical assistance with environmental site characterization and remediation at former CCC/USDA grain storage facilities. Argonne issued a ''Master Work Plan'' (Argonne 2002) to provide general guidance for all investigations at former CCC/USDA facilities in Kansas. The ''Master Work Plan'', approved by the KDHE, contains the materials common to investigations at all locations in Kansas. This document must be consulted for the complete details of plans for this work associated with the former CCC/USDA facility at Barnes.

  8. Planning for hybrid-cycle OTEC experiments using the HMTSTA test facility at the Natural Energy Laboratory of Hawaii

    Science.gov (United States)

    Panchal, C.; Rabas, T.; Genens, L.

    The U.S. Department of Energy has built an experimental apparatus for studying the open-cycle Ocean Thermal Energy Conversion (OC-OTEC) system. Experiments using warm and cold seawater are currently underway to validate the performance predictions for an OC-TEC flash evaporator, surface condenser, and direct-contact condenser. The hybrid cycle is another OTEC option that produces both power and desalinated water, it is comparable in capital cost to OC-OTEC, and it eliminates the problems associated with the large steam turbine. Means are presented or modifying the existing apparatus to conduct similar experiments on hybrid-cycle OTEC heat exchangers. These data are required to validate predictive methods of the components and for the system integration that were identified in an earlier study of hybrid-cycle OTEC power plants.

  9. Micro Analyses AC/DC Hybrid Power Grid Planning and Design%交直流混合微电网的规划设计

    Institute of Scientific and Technical Information of China (English)

    王红阳

    2016-01-01

    由于交直流混合微电网可以减少多重变换器运行所产生的损耗、谐波电流,同时能够提高系统的经济性、可靠性,所以现在已成为当今微电网的主要发展方向。笔者将从电压等级、接地方式、母线结构和网络拓扑等角度,探讨交直流混合微电网的规划设计,以供有意对交直流混合微电网进行深入研究的专家学者参考。%Due to micro AC/DC hybrid power grid can reduce multiple converter loss, harmonic current generated by the operation, at the same time can improve the efficiency of system, the reliability, so now it is the main direction of micro grid today. Grounding method, the author will from voltage grade, bus structure and network topology of micro AC/DC hybrid power grid planning and design were discussed, for the intention to conduct the thorough research to the micro AC/DC hybrid power grid in the experts and scholars to provide the reference.

  10. Technical management plan for sample generation, analysis, and data review for Phase 2 of the Clinch River Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, C.C.; Benson, S.B. [Oak Ridge National Lab., TN (United States); Beeler, D.A. [Peer Consultants, Inc., Oak Ridge, TN (United States)] [and others

    1994-03-01

    The Clinch River Remedial Investigation (CRRI) is designed to address the transport, fate, and distribution of waterborne contaminants (radionuclides, metals, and organic compounds) released from the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) and to assess potential risks to human health and the environment associated with these contaminants. The remedial investigation is entering Phase 2, which has the following items as its objectives: define the nature and extent of the contamination in areas downstream from the DOE ORR, evaluate the human health and ecological risks posed by these contaminants, and perform preliminary identification and evaluation of potential remediation alternatives. This plan describes the requirements, responsibilities, and roles of personnel during sampling, analysis, and data review for the Clinch River Environmental Restoration Program (CR-ERP). The purpose of the plan is to formalize the process for obtaining analytical services, tracking sampling and analysis documentation, and assessing the overall quality of the CR-ERP data collection program to ensure that it will provide the necessary building blocks for the program decision-making process.

  11. Engineering task plan for rotary mode core sampling exhausters CAM high radiation interlock

    Energy Technology Data Exchange (ETDEWEB)

    BOGER, R.M.

    1999-05-19

    The Rotary Mode Core Sampling (RMCS) system is primarily made up of the Rotary Mode Core Sample Trucks (RMCST) and the RMCS Exhausters. During RMCS operations an Exhauster is connected to a tank riser and withdraws gases from the tank dome vapor space at approximately 200 Standard Cubic Feet per Minute (SCFM). The gases are passed through two High Efficiency Particulate Air (HEPA) filters before passing out the exhaust stack to the atmosphere. A Continuous Air Monitor (CAM) monitors the exhaust gases in the exhaust stack for beta particle and gamma radiation. The CAM has a high radiation alarm output and a detector fail alarm output. The CAM alarms are currently connected to the data logger only. The CAM alarms require operator response per procedure LMHC 1998 but no automatic functions are initiated by the CAM alarms. Currently, there are three events that can cause an automatic shut down of the Exhauster. These are, Low Tank Pressure, Highnow Stack Flow and High HEPA Filter Differential Pressure (DP).

  12. Automatic Motion Generation for Robotic Milling Optimizing Stiffness with Sample-Based Planning

    Directory of Open Access Journals (Sweden)

    Julian Ricardo Diaz Posada

    2017-01-01

    Full Text Available Optimal and intuitive robotic machining is still a challenge. One of the main reasons for this is the lack of robot stiffness, which is also dependent on the robot positioning in the Cartesian space. To make up for this deficiency and with the aim of increasing robot machining accuracy, this contribution describes a solution approach for optimizing the stiffness over a desired milling path using the free degree of freedom of the machining process. The optimal motion is computed based on the semantic and mathematical interpretation of the manufacturing process modeled on its components: product, process and resource; and by configuring automatically a sample-based motion problem and the transition-based rapid-random tree algorithm for computing an optimal motion. The approach is simulated on a CAM software for a machining path revealing its functionality and outlining future potentials for the optimal motion generation for robotic machining processes.

  13. Y-12 Groundwater Protection Program Groundwater And Surface Water Sampling And Analysis Plan For Calendar Year 2010

    Energy Technology Data Exchange (ETDEWEB)

    Elvado Environmental LLC

    2009-09-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2010 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2010 will be in accordance with requirements of DOE Order 540.1A and the following goals: (1) to protect the worker, the public, and the environment; (2) to maintain surveillance of existing and potential groundwater contamination sources; (3) to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are most likely to migrate beyond the Oak Ridge Reservation property line; (4) to identify and characterize long-term trends in groundwater quality at Y-12; and (5) to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2010 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation. Modifications to the CY 2010 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells or may add or remove wells from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and analysis plan

  14. High-contrast X-ray micro-tomography of low attenuation samples using large area hybrid semiconductor pixel detector array of 10 × 5 Timepix chips

    Science.gov (United States)

    Karch, J.; Krejci, F.; Bartl, B.; Dudak, J.; Kuba, J.; Kvacek, J.; Zemlicka, J.

    2016-01-01

    State-of-the-art hybrid pixel semiconductor detectors provide excellent imaging properties such as unlimited dynamic range, high spatial resolution, high frame rate and energy sensitivity. Nevertheless, a limitation in the use of these devices for imaging has been the small sensitive area of a few square centimetres. In the field of microtomography we make use of a large area pixel detector assembled from 50 Timepix edgeless chips providing fully sensitive area of 14.3 × 7.15 cm2. We have successfully demonstrated that the enlargement of the sensitive area enables high-quality tomographic measurements of whole objects with high geometrical magnification without any significant degradation in resulting reconstructions related to the chip tilling and edgeless sensor technology properties. The technique of micro-tomography with the newly developed large area detector is applied for samples formed by low attenuation, low contrast materials such a seed from Phacelia tanacetifolia, a charcoalified wood sample and a beeswax seal sample.

  15. Nonhydrolytic sol-gel approach to facile creation of surface-bonded zirconia organic-inorganic hybrid coatings for sample preparation. Ι. Capillary microextraction of catecholamine neurotransmitters.

    Science.gov (United States)

    Alhendal, Abdullah; Mengis, Stephanie; Matthews, Jacob; Malik, Abdul

    2016-10-14

    Nonhydrolytic sol-gel (NHSG) route was used for the creation of novel zirconia-polypropylene oxide (ZrO2-PPO) sol-gel hybrid sorbents in the form of surface coatings for the extraction and preconcentration of catecholamine neurotransmitters and molecules structurally related to their deaminated metabolites. In comparison to other sorbents made of inorganic transition metal oxides, the presented hybrid organic-inorganic sorbents facilitated reversible sorption properties that allowed for efficient desorption of the extracted analytes by LC-MS compatible mobile phases. The presented sol-gel hybrid sorbents effectively overcame the major drawbacks of traditional silica- or polymer-based sorbents by providing superior pH stability (pH range: 0-14), and a variety of intermolecular interactions. Nonaqueous sol-gel treatment of PPO with ZrCl4 was employed for the derivatization of the terminal hydroxyl groups on PPO, providing zirconium trichloride-containing end groups characterized by enhanced sol-gel reactivity. NHSG ZrO2-PPO sorbent provided excellent microextraction performance for catecholamines, low detection limits (5.6-9.6pM), high run-to-run reproducibility (RSD 0.6-5.1%), high desorption efficiency (95.0-99.5%) and high enrichment factors (∼1480-2650) for dopamine and epinephrine, respectively, extracted from synthetic urine samples. The presented sol-gel sorbents provided effective alternative to conventional extraction media providing unique physicochemical characteristics and excellent extraction capability.

  16. Advances in organic-inorganic hybrid sorbents for the extraction of organic and inorganic pollutants in different types of food and environmental samples.

    Science.gov (United States)

    Ng, Nyuk-Ting; Kamaruddin, Amirah Farhan; Wan Ibrahim, Wan Aini; Sanagi, Mohd Marsin; Abdul Keyon, Aemi S

    2017-08-21

    The efficiency of the extraction and removal of pollutants from food and the environment has been an important issue in analytical science. By incorporating inorganic species into an organic matrix, a new material known as an organic-inorganic hybrid material is formed. As it possesses high selectivity, permeability, and mechanical and chemical stabilities, organic-inorganic hybrid materials constitute an emerging research field and have become popular to serve as sorbents in various separaton science methods. Here, we review recent significant advances in analytical solid-phase extraction employing organic-inorganic composite/nanocomposite sorbents for the extraction of organic and inorganic pollutants from various types of food and environmental matrices. The physicochemical characteristics, extraction properties, and analytical performances of sorbents are discussed; including morphology and surface characteristics, types of functional groups, interaction mechanism, selectivity and sensitivity, accuracy, and regeneration abilities. Organic-inorganic hybrid sorbents combined with extraction techniques are highly promising for sample preparation of various food and environmental matrixes with analytes at trace levels. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Y-12 Groundwater Protection Program Groundwater and Surface water Sampling and Analysis Plan for Calendar Year 2006

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2006-01-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2006 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring performed by the GWPP during CY 2006 will be in accordance with DOE Order 540.1 requirements and the following goals: {sm_bullet} to maintain surveillance of existing and potential groundwater contamination sources; {sm_bullet} to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are most likely to migrate beyond the Oak Ridge Reservation property line; {sm_bullet} to identify and characterize long-term trends in groundwater quality at Y-12; and ! to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring during CY 2006 will be performed primarily in three hydrogeologic regimes at Y-12: the Bear Creek Hydrogeologic Regime (Bear Creek Regime), the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime), and the Chestnut Ridge Hydrogeologic Regime (Chestnut Ridge Regime). The Bear Creek and East Fork regimes are located in Bear Creek Valley, and the Chestnut Ridge Regime is located south of Y-12 (Figure A.1). Additional surface water monitoring will be performed north of Pine Ridge, along the boundary of the Oak Ridge Reservation (Figure A.1). Modifications to the CY 2006 monitoring program may be necessary during implementation. Changes in programmatic requirements may alter the analytes specified for selected monitoring wells or may add or remove wells from the planned monitoring network. All modifications to the monitoring program will be approved by the Y-12 GWPP manager and documented as addenda to this sampling and analysis plan. The following sections of

  18. A NON-ZERO SAMPLING PLAN FOR THE MODERATION OF EXAMINATION PAPERS

    Directory of Open Access Journals (Sweden)

    S.A. Van Wijk

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: The moderation of examination answer books is an area where quality assurance is essential, and should be employed to ensure that an examination paper’s standard, content and span, marking, etc. are fair and reasonable. A scientific procedure is given for finding the minimum number of answer books to moderate (sample size so that the statement – that no answer book in a set will contain more than a prespecified proportion of errors – can be made with a pre-specified confidence. The procedure is an extension and enhancement of previous research [7], and guarantees a statistical statement in all cases.

    AFRIKAANSE OPSOMMING: Gehalteversekering is belangrik by die moderering van eksamen antwoordstelle om te verseker dat die standaard, inhoud, omvang en akkuraatheid van eksaminering billik en volgens aanvaarbare norme verloop het. ’n Wetenskaplike prosedure word voorgestel waarvolgens die minimum getal antwoordstelle (steekproefgrootte vir moderering bepaal kan word sodat die stelling dat geen antwoordstel in ’n groep meer as ’n vooraf-gespesifiseerde aantal foute sal bevat nie met ‘n voorafgespesifiseerde vlak van vertroue gemaak kan word. Die prosedure is ’n uitbreiding en verfyning van vorige navorsing [7], en waarborg in alle gevalle ’n statistiese uitspraak.

  19. Numerical and structural genomic aberrations are reliably detectable in tissue microarrays of formalin-fixed paraffin-embedded tumor samples by fluorescence in-situ hybridization.

    Directory of Open Access Journals (Sweden)

    Heike Horn

    Full Text Available Few data are available regarding the reliability of fluorescence in-situ hybridization (FISH, especially for chromosomal deletions, in high-throughput settings using tissue microarrays (TMAs. We performed a comprehensive FISH study for the detection of chromosomal translocations and deletions in formalin-fixed and paraffin-embedded (FFPE tumor specimens arranged in TMA format. We analyzed 46 B-cell lymphoma (B-NHL specimens with known karyotypes for translocations of IGH-, BCL2-, BCL6- and MYC-genes. Locus-specific DNA probes were used for the detection of deletions in chromosome bands 6q21 and 9p21 in 62 follicular lymphomas (FL and six malignant mesothelioma (MM samples, respectively. To test for aberrant signals generated by truncation of nuclei following sectioning of FFPE tissue samples, cell line dilutions with 9p21-deletions were embedded into paraffin blocks. The overall TMA hybridization efficiency was 94%. FISH results regarding translocations matched karyotyping data in 93%. As for chromosomal deletions, sectioning artefacts occurred in 17% to 25% of cells, suggesting that the proportion of cells showing deletions should exceed 25% to be reliably detectable. In conclusion, FISH represents a robust tool for the detection of structural as well as numerical aberrations in FFPE tissue samples in a TMA-based high-throughput setting, when rigorous cut-off values and appropriate controls are maintained, and, of note, was superior to quantitative PCR approaches.

  20. Numerical and structural genomic aberrations are reliably detectable in tissue microarrays of formalin-fixed paraffin-embedded tumor samples by fluorescence in-situ hybridization.

    Science.gov (United States)

    Horn, Heike; Bausinger, Julia; Staiger, Annette M; Sohn, Maximilian; Schmelter, Christopher; Gruber, Kim; Kalla, Claudia; Ott, M Michaela; Rosenwald, Andreas; Ott, German

    2014-01-01

    Few data are available regarding the reliability of fluorescence in-situ hybridization (FISH), especially for chromosomal deletions, in high-throughput settings using tissue microarrays (TMAs). We performed a comprehensive FISH study for the detection of chromosomal translocations and deletions in formalin-fixed and paraffin-embedded (FFPE) tumor specimens arranged in TMA format. We analyzed 46 B-cell lymphoma (B-NHL) specimens with known karyotypes for translocations of IGH-, BCL2-, BCL6- and MYC-genes. Locus-specific DNA probes were used for the detection of deletions in chromosome bands 6q21 and 9p21 in 62 follicular lymphomas (FL) and six malignant mesothelioma (MM) samples, respectively. To test for aberrant signals generated by truncation of nuclei following sectioning of FFPE tissue samples, cell line dilutions with 9p21-deletions were embedded into paraffin blocks. The overall TMA hybridization efficiency was 94%. FISH results regarding translocations matched karyotyping data in 93%. As for chromosomal deletions, sectioning artefacts occurred in 17% to 25% of cells, suggesting that the proportion of cells showing deletions should exceed 25% to be reliably detectable. In conclusion, FISH represents a robust tool for the detection of structural as well as numerical aberrations in FFPE tissue samples in a TMA-based high-throughput setting, when rigorous cut-off values and appropriate controls are maintained, and, of note, was superior to quantitative PCR approaches.

  1. Corrective Action Investigation Plan for Corrective Action Unit 565: Stored Samples, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    Wickline, Alfred; McCall, Robert

    2006-08-01

    Corrective Action Unit (CAU) 565 is located in Area 26 of the Nevada Test Site, which is 65 miles northwest of Las Vegas, Nevada. Corrective Action Unit 565 is comprised of one corrective action site (CAS) listed--CAS 26-99-04, Ground Zero Soil Samples. This site is being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend closure of CAU 565. Additional information will be obtained by conducting a corrective action investigation before evaluating closure objectives and selecting the appropriate corrective action. The results of the field investigation will support closure and waste management decisions that will be presented in the Corrective Action Decision Document/Closure Report. The site will be investigated based on the data quality objectives (DQOs) developed on June 1, 2006, by representatives of the Nevada Division of Environmental Protection; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Stoller-Navarro Joint Venture; and Bechtel Nevada. The DQO process was utilized to identify and define the type, amount, and quality of data needed to develop and evaluate closure for CAU 565. Appendix A provides a detailed discussion of the DQO methodology and the DQOs specific to this CAS. The scope of the corrective action investigation for CAU 565 includes the following activities: (1) Remove stored samples, shelves, and debris from the interior of Building 26-2106. (2) Perform field screening on stored samples, shelves, and debris. (3) Dispose of stored samples, shelves, and debris. (4) Collect samples of investigation-derived waste, as needed, for waste management purposes. (5) Conduct radiological surveys of Building 26-2106 in accordance with the requirements in the ''NV/YMP Radiological Control Manual'' to determine if there is residual radiological contamination that would prevent the release of the building for

  2. Tank 241-AZ-101 and Tank 241-AZ-102 Airlift Circulator Operation Vapor Sampling and Analysis Plan

    Energy Technology Data Exchange (ETDEWEB)

    TEMPLETON, A.M.

    1999-12-07

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of the tank 241-AZ-101 and 241-AZ-102 airlift circulators (ALCs) and during the initial operation (''bump'') of the tank 241-AZ-101 mixer pumps. The purpose of the ALC operation is to support portions of the operational test procedure (OTP) for Project W-030 (OTP-W030-001) and to perform functional test in support of Project W-151. Project W-030 is the 241-A-702 ventilation upgrade project (241-142-702) and Project W-151 is the 241-AZ-101 Mixer Pump Test. The functional tests will check the operability of the tank 241-AZ-101 ALCs. Process Memo's No. 2E98-082 and No. 2E99-001 (LMHC 1999a, LMHC 1999b) direct the operation of the ALCs and the Industrial Hygiene monitoring respectively. A series of tests will be conducted in which the ALCs in tanks 241-AZ-101 and 241-AZ-102 will be operated at different air flow rates. Vapor samples will be obtained to determine constituents that may be present in the tank headspace during ALC operation at tanks 241-AZ-101 and 241-AZ-102 as the waste is disturbed. During the testing, vapor samples will be obtained from the headspace of tanks 241-AZ-101 and 241-AZ-102 via the unused port on the standard hydrogen monitoring system (SHMS). In addition the last two vapor samples will be collected from the headspace of tank 241-AZ-101 during the operation of the mixer pumps. Each mixer pump will be operated for approximately 5 minutes. Results will be used to provide the waste feed delivery program with environmental air permitting data for tank waste disturbing activities. Because of radiological concerns, the samples will be filtered for particulates. It is recognized that this may remove some organic compounds. The following sections provide the general methodology and procedures to be used in the

  3. Sampling and analysis plan for the Bear Creek Valley Boneyard/Burnyard Accelerated Action Project, Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In the Bear Creek Valley Watershed Remedial Investigation, the Boneyard/Burnyard was identified as the source of the largest releases of uranium into groundwater and surface water in Bear Creek Valley. The proposed action for remediation of this site is selective excavation and removal of source material and capping of the remainder of the site. The schedule for this action has been accelerated so that this is the first remedial action planned to be implemented in the Bear Creek Valley Record of Decision. Additional data needs to support design of the remedial action were identified at a data quality objectives meeting held for this project. Sampling at the Boneyard/Burnyard will be conducted through the use of a phased approach. Initial or primary samples will be used to make in-the-field decisions about where to locate follow-up or secondary samples. On the basis of the results of surface water, soil, and groundwater analysis, up to six test pits will be dug. The test pits will be used to provide detailed descriptions of source materials and bulk samples. This document sets forth the requirements and procedures to protect the personnel involved in this project. This document also contains the health and safety plan, quality assurance project plan, waste management plan, data management plan, implementation plan, and best management practices plan for this project as appendices.

  4. Implementing reduced-risk integrated pest management in fresh-market cabbage: influence of sampling parameters, and validation of binomial sequential sampling plans for the cabbage looper (Lepidoptera Noctuidae).

    Science.gov (United States)

    Burkness, Eric C; Hutchison, W D

    2009-10-01

    Populations of cabbage looper, Trichoplusiani (Lepidoptera: Noctuidae), were sampled in experimental plots and commercial fields of cabbage (Brasicca spp.) in Minnesota during 1998-1999 as part of a larger effort to implement an integrated pest management program. Using a resampling approach and the Wald's sequential probability ratio test, sampling plans with different sampling parameters were evaluated using independent presence/absence and enumerative data. Evaluations and comparisons of the different sampling plans were made based on the operating characteristic and average sample number functions generated for each plan and through the use of a decision probability matrix. Values for upper and lower decision boundaries, sequential error rates (alpha, beta), and tally threshold were modified to determine parameter influence on the operating characteristic and average sample number functions. The following parameters resulted in the most desirable operating characteristic and average sample number functions; action threshold of 0.1 proportion of plants infested, tally threshold of 1, alpha = beta = 0.1, upper boundary of 0.15, lower boundary of 0.05, and resampling with replacement. We found that sampling parameters can be modified and evaluated using resampling software to achieve desirable operating characteristic and average sample number functions. Moreover, management of T. ni by using binomial sequential sampling should provide a good balance between cost and reliability by minimizing sample size and maintaining a high level of correct decisions (>95%) to treat or not treat.

  5. Hybrid Motion Planning Method for Autonomous Robots Using Kinect Based Sensor Fusion and Virtual Plane Approach in Dynamic Environments

    Directory of Open Access Journals (Sweden)

    Doopalam Tuvshinjargal

    2015-01-01

    Full Text Available A new reactive motion planning method for an autonomous vehicle in dynamic environments is proposed. The new dynamic motion planning method combines a virtual plane based reactive motion planning technique with a sensor fusion based obstacle detection approach, which results in improving robustness and autonomy of vehicle navigation within unpredictable dynamic environments. The key feature of the new reactive motion planning method is based on a local observer in the virtual plane which allows the effective transformation of complex dynamic planning problems into simple stationary in the virtual plane. In addition, a sensor fusion based obstacle detection technique provides the pose estimation of moving obstacles by using a Kinect sensor and a sonar sensor, which helps to improve the accuracy and robustness of the reactive motion planning approach in uncertain dynamic environments. The performance of the proposed method was demonstrated through not only simulation studies but also field experiments using multiple moving obstacles even in hostile environments where conventional method failed.

  6. A novel IgY-Aptamer hybrid system for cost-effective detection of SEB and its evaluation on food and clinical samples.

    Science.gov (United States)

    Mudili, Venkataramana; Makam, Shivakiran S; Sundararaj, Naveen; Siddaiah, Chandranayaka; Gupta, Vijai Kumar; Rao, Putcha V Lakshmana

    2015-10-19

    In the present study, we introduce a novel hybrid sandwich-ALISA employing chicken IgY and ssDNA aptamers for the detection of staphylococcal enterotoxin B (SEB). Cloning, expression and purification of the full length recombinant SEB was carried out. Anti-SEB IgY antibodies generated by immunizing white leg-horn chickens with purified recombinant SEB protein and were purified from the immunized egg yolk. Simultaneously, ssDNA aptamers specific to the toxin were prepared by SELEX method on microtiter well plates. The sensitivity levels of both probe molecules i.e., IgY and ssDNA aptamers were evaluated. We observed that the aptamer at 250 ngmL(-1) concentration could detect the target antigen at 50 ngmL(-1) and the IgY antibodies at 250 ngmL(-1), could able to detect 100 ngmL(-1) antigen. We further combined both the probes to prepare a hybrid sandwich aptamer linked immune sorbent assay (ALISA) wherein the IgY as capturing molecule and biotinylated aptamer as revealing probe. Limit of detection (LOD) for the developed method was determined as 50 ngmL(-1). Further, developed method was evaluated with artificially SEB spiked milk and natural samples and obtained results were validated with PCR. In conclusion, developed ALISA method may provide cost-effective and robust detection of SEB from food and environmental samples.

  7. Hybrid monolith sorbent of polypyrrole-coated graphene oxide incorporated into a polyvinyl alcohol cryogel for extraction and enrichment of sulfonamides from water samples.

    Science.gov (United States)

    Chullasat, Kochaporn; Nurerk, Piyaluk; Kanatharana, Proespichaya; Kueseng, Pamornrat; Sukchuay, Thanyaporn; Bunkoed, Opas

    2017-04-08

    A hybrid monolith sorbent of polypyrrole-coated graphene oxide embedded in polyvinyl alcohol cryogel was prepared and used as an effective solid phase extraction sorbent for the determination of trace sulfonamides. The large surface areas with many adsorption sites of polypyrrole and graphene oxide facilitated the high adsorption of sulfonamides via hydrogen bonding, π-π and hydrophobic interactions. The high porosity of the polyvinyl alcohol cryogel helped to reduce the back pressure that occurs in a conventional packed solid phase extraction cartridge. The effecting parameters on the extraction efficiency including the type of sorbent, the polymerization time, desorption conditions, the sample pH, the sample volume, the sample flow rate, and ionic strength were investigated and optimized. Under the optimum conditions, the developed method provided a wide linear range from 0.20 to 100.0 μg L(-1) for sulfadiazine, sulfathiazole and sulfamerazine; and from 0.10 to 100 μg L(-1) for sulfamethazine, sulfamonomethoxine and sulfadimethoxine. The limits of detection were 0.20 μg L(-1) for sulfadiazine, sulfathiazole and sulfamerazine; and 0.10 μg L(-1) for sulfamethazine, sulfamonomethoxine and sulfadimethoxine. The developed hybrid monolith polypyrrole-coated graphene oxide embedded in the polyvinyl alcohol cryogel sorbent provided good recoveries in the range of 85.5-99.0% with RSDs of less than 5.0%. The sorbent offered a good reproducibility, was robust and can be reused at least 10 times. It was successfully applied for the extraction and enrichment of sulfonamides from normal and supplemented water samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. A hybrid electron and photon IMRT planning technique that lowers normal tissue integral patient dose using standard hardware.

    Science.gov (United States)

    Rosca, Florin

    2012-06-01

    To present a mixed electron and photon IMRT planning technique using electron beams with an energy range of 6-22 MeV and standard hardware that minimizes integral dose to patients for targets as deep as 7.5 cm. Ten brain cases, two lung, a thyroid, an abdominal, and a parotid case were planned using two planning techniques: a photon-only IMRT (IMRT) versus a mixed modality treatment (E+IMRT) that includes an enface electron beam and a photon IMRT portion that ensures a uniform target coverage. The electron beam is delivered using a regular cutout placed in an electron cone. The electron energy was chosen to provide a good trade-off between minimizing integral dose and generating a uniform, deliverable plan. The authors choose electron energies that cover the deepest part of PTV with the 65%-70% isodose line. The normal tissue integral dose, the dose for ring structures around the PTV, and the volumes of the 75%, 50%, and 25% isosurfaces were used to compare the dose distributions generated by the two planning techniques. The normal tissue integral dose was lowered by about 20% by the E+IMRT plans compared to the photon-only IMRT ones for most studied cases. With the exception of lungs, the dose reduction associated to the E+IMRT plans was more pronounced further away from the target. The average dose ratio delivered to the 0-2 cm and the 2-4 cm ring structures for brain patients for the two planning techniques were 89.6% and 70.8%, respectively. The enhanced dose sparing away from the target for the brain patients can also be observed in the ratio of the 75%, 50%, and 25% isodose line volumes for the two techniques, which decreases from 85.5% to 72.6% and further to 65.1%, respectively. For lungs, the lateral electron beams used in the E+IMRT plans were perpendicular to the mostly anterior/posterior photon beams, generating much more conformal plans. The authors proved that even using the existing electron delivery hardware, a mixed electron/photon planning

  9. Enhanced Sampling of an Atomic Model with Hybrid Nonequilibrium Molecular Dynamics-Monte Carlo Simulations Guided by a Coarse-Grained Model.

    Science.gov (United States)

    Chen, Yunjie; Roux, Benoît

    2015-08-11

    Molecular dynamics (MD) trajectories based on a classical equation of motion provide a straightforward, albeit somewhat inefficient approach, to explore and sample the configurational space of a complex molecular system. While a broad range of techniques can be used to accelerate and enhance the sampling efficiency of classical simulations, only algorithms that are consistent with the Boltzmann equilibrium distribution yield a proper statistical mechanical computational framework. Here, a multiscale hybrid algorithm relying simultaneously on all-atom fine-grained (FG) and coarse-grained (CG) representations of a system is designed to improve sampling efficiency by combining the strength of nonequilibrium molecular dynamics (neMD) and Metropolis Monte Carlo (MC). This CG-guided hybrid neMD-MC algorithm comprises six steps: (1) a FG configuration of an atomic system is dynamically propagated for some period of time using equilibrium MD; (2) the resulting FG configuration is mapped onto a simplified CG model; (3) the CG model is propagated for a brief time interval to yield a new CG configuration; (4) the resulting CG configuration is used as a target to guide the evolution of the FG system; (5) the FG configuration (from step 1) is driven via a nonequilibrium MD (neMD) simulation toward the CG target; (6) the resulting FG configuration at the end of the neMD trajectory is then accepted or rejected according to a Metropolis criterion before returning to step 1. A symmetric two-ends momentum reversal prescription is used for the neMD trajectories of the FG system to guarantee that the CG-guided hybrid neMD-MC algorithm obeys microscopic detailed balance and rigorously yields the equilibrium Boltzmann distribution. The enhanced sampling achieved with the method is illustrated with a model system with hindered diffusion and explicit-solvent peptide simulations. Illustrative tests indicate that the method can yield a speedup of about 80 times for the model system and up

  10. A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

    National Research Council Canada - National Science Library

    Pontikos, Nikolas; Smyth, Deborah J; Schuilenburg, Helen; Howson, Joanna M M; Walker, Neil M; Burren, Oliver S; Guo, Hui; Onengut-Gumuscu, Suna; Chen, Wei-Min; Concannon, Patrick; Rich, Stephen S; Jayaraman, Jyothi; Jiang, Wei; Traherne, James A; Trowsdale, John; Todd, John A; Wallace, Chris

    2014-01-01

    .... Quantitative Polymerase Chain Reaction (qPCR) assays address this issue. However, their cost is prohibitive at the sample sizes required for detecting effects typically observed in complex genetic diseases...

  11. Modelling condom use: Does the theory of planned behaviour explain condom use in a low risk, community sample?

    Science.gov (United States)

    Thomas, Joanna; Shiels, Chris; Gabbay, Mark B

    2014-01-01

    To date, most condom research has focused on young or high-risk groups, with little evidence about influences on condom use amongst lower-risk community samples. These groups are not risk free and may still wish to negotiate safer sex; yet the considerations involved could be different from those in higher-risk groups. Our research addresses this gap: We report a cross-sectional questionnaire study enquiring about recent condom use and future use intentions in community settings. Our sample (n = 311) purposively included couples in established relationships, known to be condom users. Items included demographics, sexual history and social-cognitive variables taken from the theory of planned behaviour. The strongest association with condom use/use intentions amongst our respondents was sexual partner's perceived willingness to use them. This applied across both univariate and multivariate analyses. Whilst most social-cognitive variables (attitudes; self-efficacy and peer social norms) were significant in univariate analyses, this was not supported in multivariate regression. Of the social-cognitive variables, only "condom-related attitudes" were retained in the model explaining recent condom use, whilst none of them entered the model explaining future use intentions. Further analysis showed that attitudes concerning pleasure, identity stigma and condom effectiveness were most salient for this cohort. Our results suggest that, in community samples, the decision to use a condom involves different considerations from those highlighted in previous research. Explanatory models for established couples should embrace interpersonal perspectives, emphasising couple-factors rather than individual beliefs. Messages to this cohort could usefully focus on negotiation skills, condom advantages (other than disease prevention) and reducing the stigma associated with use.

  12. 混合变量系统基于MCMC的自适应重要抽样法%Adaptive Importance Sampling of Hybrid Variable Systems Based on MCMC

    Institute of Scientific and Technical Information of China (English)

    王进玲; 曾声奎; 马纪明; 庞怡

    2012-01-01

    The occurrence of key failures in a system may cause the system to degrade into different discrete states of performance. The classical importance sampling method based on Markov chain Monte Carlo (MCMC) can only be applied to a continuous variable system and cannot resolve the problem of mixed systems including discrete variables. Therefore, an improved adaptive importance sampling method based on MCMC is proposed to support the efficient simulation of system performance reliability. First, a failure space is constructed by combining different failure domains, and Markov simulation samples are achieved by the initial sample wandering in the failure space. Second, with a comprehensive consideration of continuous and discrete variables, a hybrid sampling density function is obtained through kernel density evaluation. Then, importance sampling simulation is operated according to the last hybrid sampling density function and the performance reliability is computed. Finally, the simulation efficiency is analyzed in theory. The validity and high efficiency of the proposed method are demonstrated by the case of an electro-hydrostatic actuator (EHA) system.%系统关键故障的发生,会导致系统处于各种离散性能降级状态.针对传统的基于马尔可夫链蒙特卡罗( Markov chain Monte Carlo,MCMC)的自适应重要抽样法只适用于连续变量系统的不足,提出考虑混合变量的基于MCMC的自适应重要抽样法,以支持系统性能可靠性的高效仿真.该方法首先将由关键故障产生的不同失效域组成失效空间,并通过初始样本点在失效空间中随机游走构造马尔可夫链模拟样本;然后综合考虑连续变量与离散变量,利用核密度估计构建混合核抽样密度函数;再根据该密度函数进行重要抽样仿真并计算系统的性能可靠性;最后对该方法的仿真效率进行理论分析.通过电液舵机(Electro-Hydrostatic Actuator,EHA)案例对方法的正确性和仿真效率进行验证.

  13. An Extended Theory of Planned Behavior (TPB Used to Predict Smoking Behavior Among a Sample of Iranian Medical Students

    Directory of Open Access Journals (Sweden)

    Karimy

    2015-09-01

    Full Text Available Background Smoking among the youth is an important public health concern. Although several studies have investigated the correlates of smoking behavior, no theory-based study has particularly assessed this problem among medical students. Objectives This study aimed to evaluate the efficacy of the extended theory of planned behavior (TPB to predict smoking behavior among a sample of Iranian medical students. Patients and Methods This is a cross-sectional study carried out in Ahvaz, Iran, 2014. The data were collected through a self-administered questionnaire, which included items on demographics, smoking behavior, and components of the TPB model (attitude, subjective norms, perceived behavior control, and intention, and an added construct on smoking refusal skill. Data were analyzed using descriptive correlation, and linear regression statistics by SPSS, version 16. Results One hundred and seventy medical students with a mean age of 21.25 (SD = 2.9 years were enrolled in the study. Of them, 24 (13.5% students were smokers. All components of the TPB model and smoking refusal skill were statistically significant as to intention to smoke (P < 0.001. The TPB constructs with and without smoking refusal skill accounted for 77% (adjusted R2 and 78% of the variance observed for intention to smoke, respectively. The results also revealed the highest weight for perceived behavior control (β= -0.40. Conclusions The findings of this study indicated that all TPB variables are useful tools for prediction of the smoking behaviors among students. Particularly, students’ perceived behavioral control and attitudes towards smoking were found to be important determinants of smoking intentions. Thus, the findings could be used for planning effective tobacco control programs targeting University students.

  14. Magnetic solid phase extraction of gemfibrozil from human serum and pharmaceutical wastewater samples utilizing a β-cyclodextrin grafted graphene oxide-magnetite nano-hybrid.

    Science.gov (United States)

    Abdolmohammad-Zadeh, Hossein; Talleb, Zeynab

    2015-03-01

    A magnetic solid phase extraction method based on β-cyclodextrin (β-CD) grafted graphene oxide (GO)/magnetite (Fe3O4) nano-hybrid as an innovative adsorbent was developed for the separation and pre-concentration of gemfibrozil prior to its determination by spectrofluorometry. The as-prepared β-CD/GO/Fe3O4 nano-hybrid possesses the magnetism property of Fe3O4 nano-particles that makes it easily manipulated by an external magnetic field. On the other hand, the surface modification of GO by β-CD leads to selective separation of the target analyte from sample matrices. The structure and morphology of the synthesized adsorbent were characterized using powder X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The experimental factors affecting the extraction/pre-concentration and determination of the analyte were investigated and optimized. Under the optimized experimental conditions, the calibration graph was linear in the range between 10 and 5000 pg mL(-1) with a correlation coefficient of 0.9989. The limit of detection and enrichment factor for gemfibrozil were 3 pg mL(-1) and 100, respectively. The maximum sorption capacity of the adsorbent for gemfibrozil was 49.8 mg g(-1). The method was successfully applied to monitoring gemfibrozil in human serum and pharmaceutical wastewaters samples with recoveries in the range of 96.0-104.0% for the spiked samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Evaluation of the Punch-it™ NA-Sample kit for detecting microbial DNA in blood culture bottles using PCR-reverse blot hybridization assay.

    Science.gov (United States)

    Kim, Jungho; Wang, Hye-Young; Kim, Seoyong; Park, Soon Deok; Yu, Kwangmin; Kim, Hyo Youl; Uh, Young; Lee, Hyeyoung

    2016-09-01

    DNA extraction efficiency affects the success of PCR-based method applications. The Punch-it™ NA-Sample kit for extracting DNA by using paper chromatography is technically easy to use and requires just two reagents and only 10min to complete. The Punch-it™ NA-Sample kit could be offered as a rapid, accurate, and convenient method for extracting bacterial and fungal DNA from blood culture bottles. We compared the efficiencies of the commercial kit (Punch-it™ NA-Sample kit) and an in-house conventional boiling method with Chelex-100 resin for DNA extraction from blood culture bottles. The efficiency of the two DNA extraction methods was assessed by PCR-reverse blot hybridization assay (PCR-REBA, REBA Sepsis-ID) for detecting Gram positive (GP) bacteria, Gram negative (GN) bacteria, and Candida species with 196 positive and 200 negative blood culture bottles. The detection limits of the two DNA extraction methods were 10(3)CFU/mL for GP bacteria, 10(3)CFU/mL for GN bacteria, and 10(4)CFU/mL for Candida. The sensitivity and specificity of the Punch-it™ NA-Sample kit by REBA Sepsis-ID were 95.4% (187/196) and 100% (200/200), respectively. The overall agreement of the two DNA extraction methods was 98.9% (392/396). Three of four samples showing discrepant results between the two extraction methods were more accurately matched up with the Punch-it™ NA-Sample kit based on conventional culture methods. The results indicated that the Punch-it™ NA-Sample kit extracted bacterial and fungal DNA in blood culture bottles and allowed extracted DNA to be used in molecular assay. Copyright © 2016. Published by Elsevier B.V.

  16. Soil sampling and analysis plan for the Bear Creek Valley Floodplain at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    This Sampling and Analysis Plan (SAP) for the Bear Creek Valley (BCV) Floodplain presents the approach and rationale for characterizing potentially contaminated soils and sediments of the Bear Creek floodplain and the impact of any contaminants on the floodplain ecosystem. In addition to this SAP, the Remedial Investigation Work Plan for Bear Creek (Y02-S600) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee (ES/ER-19&D2) presents background information pertaining to this floodplain investigation.

  17. Analysis of industry-generated data. Part 2: Risk-based sampling plan for efficient self-control of aflatoxin M₁ contamination in raw milk.

    Science.gov (United States)

    Farkas, Zsuzsa; Trevisani, Marcello; Horváth, Zsuzsanna; Serraino, Andrea; Szabó, István J; Kerekes, Kata; Szeitzné-Szabó, Mária; Ambrus, Arpád

    2014-01-01

    Aflatoxin M₁ (AFM1) contamination in 21,969 milk samples taken in Italy during 2005-08 and 2010 provided the basis for designing an early warning self-control plan. Additionally, 4148 AFM1 data points from the mycotoxin crisis (2003-04) represented the worst case. No parametric function provided a good fit for the skewed and scattered AFM1 concentrations. The acceptable reference values, reflecting the combined uncertainty of AFM1 measured in consignments consisting of milk from one to six farms, ranged from 40 to 16.7 ng kg(-1), respectively. Asymmetric control charts with these reference values, 40 and 50 ng kg(-1) warning and action limits are recommended to assess immediately the distribution of AFM1 concentration in incoming consignments. The moving window method, presented as a worked example including 5 days with five samples/day, enabled verification of compliance of production with the legal limit in 98% of the consignments at a 94% probability level. The sampling plan developed assumes consecutive analyses of samples taken from individual farms, which makes early detection of contamination possible and also immediate corrective actions if the AFM1 concentration in a consignment exceeds the reference value. In the latter case different control plans with increased sampling frequency should be applied depending on the level and frequency of contamination. As aflatoxin B₁ increases in feed at about the same time, therefore a coordinated sampling programme performed by the milk processing plants operating in a confined geographic area is more effective and economical then the individual ones. The applicability of the sample size calculation based on binomial theorem and the fast response rate resulting from the recommended sampling plan were verified by taking 1000-10,000 random samples with replacement from the experimental databases representing the normal, moderately and highly contaminated periods. The efficiency of the control plan could be

  18. A hybrid DNA extraction method for the qualitative and quantitative assessment of bacterial communities from poultry production samples

    Science.gov (United States)

    The efficacy of DNA extraction protocols can be highly dependent upon both the type of sample being investigated and the types of downstream analyses performed. Considering that the use of new bacterial community analysis techniques (e.g., microbiomics, metagenomics) is becoming more prevalent in th...

  19. Team Robot Motion Planning in Dynamics Environments Using a New Hybrid Algorithm (Honey Bee Mating Optimization-Tabu List

    Directory of Open Access Journals (Sweden)

    Mohammad Abaee Shoushtary

    2014-01-01

    Full Text Available This paper describes a new hybrid algorithm extracted from honey bee mating optimization (HBMO algorithm (for robot travelling distance minimization and tabu list technique (for obstacle avoidance for team robot system. This algorithm was implemented in a C++ programming language on a Pentium computer and simulated on simple cylindrical robots in a simulation software. The environment in this simulation was dynamic with moving obstacles and goals. The results of simulation have shown validity and reliability of new algorithm. The outcomes of simulation have shown better performance than ACO and PSO algorithm (society, nature algorithms with respect to two well-known metrics included, ATPD (average total path deviation and AUTD (average uncovered target distance.

  20. Design and sampling plan optimization for RT-qPCR experiments in plants: a case study in blueberry

    Directory of Open Access Journals (Sweden)

    Jose V Die

    2016-03-01

    Full Text Available The qPCR assay has become a routine technology in plant biotechnology and agricultural research. It is unlikely to be technically improved, but there are still challenges which center around minimizing the variability in results and transparency when reporting technical data in support of the conclusions of a study. There are a number of aspects of the pre- and post-assay workflow that contribute to variability of results. Here, through the study of the introduction of error in qPCR measurements at different stages of the workflow, we describe the most important causes of technical variability in a case study using blueberry. In this study, we found that the stage for which increasing the number of replicates would be the most beneficial depends on the tissue used. For example, we would recommend the use of more RT replicates when working with leaf tissue, while the use of more sampling (RNA extraction replicates would be recommended when working with stems or fruits to obtain the most optimal results. The use of more qPCR replicates provides the least benefit as it is the most reproducible step. By knowing the distribution of error over an entire experiment and the costs at each step, we have developed a script to identify the optimal sampling plan within the limits of a given budget. These findings should help plant scientists improve the design of qPCR experiments and refine their laboratory practices in order to conduct qPCR assays in a more reliable-manner to produce more consistent and reproducible data.

  1. Design and Sampling Plan Optimization for RT-qPCR Experiments in Plants: A Case Study in Blueberry.

    Science.gov (United States)

    Die, Jose V; Roman, Belen; Flores, Fernando; Rowland, Lisa J

    2016-01-01

    The qPCR assay has become a routine technology in plant biotechnology and agricultural research. It is unlikely to be technically improved, but there are still challenges which center around minimizing the variability in results and transparency when reporting technical data in support of the conclusions of a study. There are a number of aspects of the pre- and post-assay workflow that contribute to variability of results. Here, through the study of the introduction of error in qPCR measurements at different stages of the workflow, we describe the most important causes of technical variability in a case study using blueberry. In this study, we found that the stage for which increasing the number of replicates would be the most beneficial depends on the tissue used. For example, we would recommend the use of more RT replicates when working with leaf tissue, while the use of more sampling (RNA extraction) replicates would be recommended when working with stems or fruits to obtain the most optimal results. The use of more qPCR replicates provides the least benefit as it is the most reproducible step. By knowing the distribution of error over an entire experiment and the costs at each step, we have developed a script to identify the optimal sampling plan within the limits of a given budget. These findings should help plant scientists improve the design of qPCR experiments and refine their laboratory practices in order to conduct qPCR assays in a more reliable-manner to produce more consistent and reproducible data.

  2. A novel hybrid mode of sample injection to enhance CZE sensitivity for simultaneous determination of a pyridine-triphenylborane anti-fouling agent and its degradation products.

    Science.gov (United States)

    Kaewchuay, Netnapit; Yakushiji, Yuki; Fukushi, Keiichi; Saito, Keiitsu; Hirokawa, Takeshi

    2011-06-01

    We developed a novel hybrid sample injection mode (HSIM) that presents the combination of electrokinetic injection and vacuum injection to enhance detection sensitivity in CZE. Samples were introduced using both vacuum and electrokinetic injections simultaneously, with a water plug injected into the capillary prior to sample introduction (i.e. similarly to field-amplified sample injection, FASI). Using a sample mixture containing an anti-fouling agent applied to ship hulls, pyridine-triphenylborane and its degradation products (diphenylborinic acid, phenylboronic acid, and phenol) dissolved in ACN, the length of water plug, time, and voltage for sample introduction were optimized. The signal intensity (peak height) was found to be up to a 30-fold increased using HSIM by applying 4 kV for 4 s at the inlet end of the capillary as the cathode with supplementary vacuum in comparison with only vacuum injection for 4 s. The LODs (at a S/N of 3) for pyridine-triphenylborane, diphenylborinic acid, phenylboronic acid, and phenol were 0.88, 1.0, 21, and 23 μg/L, respectively. At the level of 0.04 mg/L, the RSDs (n=4, intra-day) for the above analytes were in the ranges of 1.9-11, 4.3-9.2, and 0.34-0.66% for peak area, peak height, and migration time, respectively. The HSIM is a simple and promising procedure useful for enhancing the sensitivity for both low-and high-mobility ions in CZE.

  3. Confirmatory Sampling and Analysis Plan for the Lower East Fork Poplar Creek operable unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    On December 21, 1989, the EPA placed the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) on the National Priorities List (NPL). On January 1, 1992, a Federal Facilities Agreement (FFA) between the DOE Field Office in Oak Ridge (DOE-OR), EPA Region IV, and the Tennessee Department of Environment and Conservation (TDEC) went into effect. This FFA establishes the procedural framework and schedule by which DOE-OR will develop, coordinate, implement and monitor environmental restoration activities on the ORR in accordance with applicable federal and state environmental regulations. The DOE-OR Environmental Restoration Program for the ORR addresses the remediation of areas both within and outside the ORR boundaries. This sampling and analysis plan focuses on confirming the cleanup of the stretch of EFPC flowing from Lake Reality at the Y-12 Plant through the City of Oak Ridge, to Poplar Creek on the ORR and its associated floodplain. Both EFPC and its floodplain have been contaminated by releases from the Y-12 Plant since the mid-1950s. Because the EFPC site-designated as an ORR operable unit (OU) under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) is included on the NPL, its remediation must follow the specific procedures mandated by CERCLA, as amended by the Superfund Amendments and Reauthorization Act in 1986.

  4. Analysis of 89 amniotic samples using fluorescent in situ hybridization%89份羊水细胞的荧光原位杂交分析

    Institute of Scientific and Technical Information of China (English)

    魏萍; 李运星; 曾兰; 陈春; 秦胜芳; 汪雪雁; 席娜; 唐书勤; 冷媚

    2013-01-01

    Objective To assess the value of fluorescent in situ hybridization (FISH) for detecting common chromosome aneuploidies in interphase nuclei of amniotic fluid cells.Methods Eighty two uncultured amniotic fluid samples and supernatants from two successfully and five unsuccessfully cultured amniotic fluid samples were analyzed with FISH.Results from standard cytogenetic analysis of 79 uncultured amniotic fluid samples and 2 successfully cultured amniotic fluid samples were compared with FISH results.Results All of the 89 samples were succeeded analyzed with FISH.Positive findings included 3 cases with trisomy 21,1 case with 47,XYY and 1 case with 69,XXX,which were consistent with results of karyotype analysis.Conclusion FISH is a rapid and accurate method for prenatal diagnosis,and can also provide a remedy to failed amniotic fluid cells culture.%目的 探讨荧光原位杂交(fluorescent in situ hybridization,FISH)技术在产前诊断中的应用价值.方法 应用FISH对82例未培养的羊水细胞、2例培养成功的羊水细胞上清液及5例培养未成功的羊水细胞上清液进行染色体非整倍体检测,以其中79例未培养羊水细胞和2例培养成功羊水细胞的常规G显带核型分析结果作为对照.结果 89例标本均成功杂交,共检出21-三体3例,超雄综合征1例,三倍体1例.羊水培养细胞核型分析结果与FISH检测结果一致.结论 将FISH应用于染色体非整倍体的产前检测具有快速、直观的优点.FISH也可作为羊水标本未培养成功的补救诊断措施.

  5. Evaluation of PCR, DNA hybridization and immunomagnetic separation — PCR for detection of Burkholderia mallei in artificially inoculated environmental samples

    OpenAIRE

    2010-01-01

    Glanders is highly contagious disease of equines, caused by Burkholderia mallei. The disease though rare, can be transmitted to humans. Here, we report a strategy for rapid detection of B. mallei from environmental samples. Different bacteriological media were evaluated and brain heart infusion broth medium with selective supplements (BHIB-SS) of penicillin (200 U/ml) and crystal violet (1:10,00000) was found to support the maximum growth of B. mallei even in the presence of other bacteria li...

  6. Determination of the influence of dispersion pattern of pesticide-resistant individuals on the reliability of resistance estimates using different sampling plans.

    Science.gov (United States)

    Shah, R; Worner, S P; Chapman, R B

    2012-10-01

    Pesticide resistance monitoring includes resistance detection and subsequent documentation/ measurement. Resistance detection would require at least one (≥1) resistant individual(s) to be present in a sample to initiate management strategies. Resistance documentation, on the other hand, would attempt to get an estimate of the entire population (≥90%) of the resistant individuals. A computer simulation model was used to compare the efficiency of simple random and systematic sampling plans to detect resistant individuals and to document their frequencies when the resistant individuals were randomly or patchily distributed. A patchy dispersion pattern of resistant individuals influenced the sampling efficiency of systematic sampling plans while the efficiency of random sampling was independent of such patchiness. When resistant individuals were randomly distributed, sample sizes required to detect at least one resistant individual (resistance detection) with a probability of 0.95 were 300 (1%) and 50 (10% and 20%); whereas, when resistant individuals were patchily distributed, using systematic sampling, sample sizes required for such detection were 6000 (1%), 600 (10%) and 300 (20%). Sample sizes of 900 and 400 would be required to detect ≥90% of resistant individuals (resistance documentation) with a probability of 0.95 when resistant individuals were randomly dispersed and present at a frequency of 10% and 20%, respectively; whereas, when resistant individuals were patchily distributed, using systematic sampling, a sample size of 3000 and 1500, respectively, was necessary. Small sample sizes either underestimated or overestimated the resistance frequency. A simple random sampling plan is, therefore, recommended for insecticide resistance detection and subsequent documentation.

  7. Bovine serum albumin-Cu(II) hybrid nanoflowers: An effective adsorbent for solid phase extraction and slurry sampling flame atomic absorption spectrometric analysis of cadmium and lead in water, hair, food and cigarette samples

    Energy Technology Data Exchange (ETDEWEB)

    Yilmaz, Erkan [Department of Chemistry, Faculty of Sciences, Erciyes University, Kayseri 38039 (Turkey); Ocsoy, Ismail [Department of Analytical Chemistry, Faculty of Pharmacy, Erciyes University, Kayseri 38039 (Turkey); Nanotechnology Research Center (ERNAM), Erciyes University, Kayseri 38039 (Turkey); Ozdemir, Nalan [Department of Chemistry, Faculty of Sciences, Erciyes University, Kayseri 38039 (Turkey); Soylak, Mustafa, E-mail: soylak@erciyes.edu.tr [Department of Chemistry, Faculty of Sciences, Erciyes University, Kayseri 38039 (Turkey)

    2016-02-04

    Herein, the synthesis of bovine serum albumin-Cu(II) hybrid nanoflowers (BSA-NFs) through the building blocks of bovine serum albumin (BSA) and copper(II) ions in phosphate buffered saline (PBS) and their use as adsorbent for cadmium and lead ions are reported. The BSA-NFs, for the first time, were efficiently utilized as novel adsorbent for solid phase extraction (SPE) of cadmium and lead ions in water, food, cigarette and hair samples. The method is based on the separation and pre-concentration of Cd(II) and Pb(II) by BSA-NFs prior to determination by slurry analysis via flame atomic absorption spectrometry (FAAS). The analytes were adsorbed on BSA-NFs under the vortex mixing and then the ion-loaded slurry was separated and directly introduced into the flame AAS nebulizer by using a hand-made micro sample introduction system to eliminate a number of drawbacks. The effects of analytical key parameters, such as pH, amount of BSA-NFs, vortexing time, sample volume, and matrix effect of foreign ions on adsorbing of Cd(II) and Pb(II) were systematically investigated and optimized. The limits of detection (LODs) for Cd(II) and Pb(II) were calculated as 0.37 μg L{sup −1} and 8.8 μg L{sup −1}, respectively. The relative standard deviation percentages (RSDs) (N = 5) for Cd(II) and Pb(II) were 7.2%, and 5.0%, respectively. The accuracy of the developed procedure was validated by the analysis of certified reference materials (TMDA-53.3 Fortified Water, TMDA-70 Fortified Water, SPS-WW2 Waste Water, NCSDC-73349 Bush Branches and Leaves) and by addition/recovery analysis. The quantitative recoveries were obtained for the analysis of certified reference materials and addition/recovery tests. The method was successfully applied to the analysis of cadmium and lead in water, food, cigarette and hair samples. - Highlights: • The synthesis of bovine serum albumin-Cu(II) hybrid nanoflowers is reported. • The nanoflowers were utilized for solid phase microextraction of

  8. From plans to actions in patient and public involvement: qualitative study of documented plans and the accounts of researchers and patients sampled from a cohort of clinical trials.

    Science.gov (United States)

    Buck, Deborah; Gamble, Carrol; Dudley, Louise; Preston, Jennifer; Hanley, Bec; Williamson, Paula R; Young, Bridget

    2014-12-04

    : Patient and public involvement (PPI) in research is increasingly required, although evidence to inform its implementation is limited. Inform the evidence base by describing how plans for PPI were implemented within clinical trials and identifying the challenges and lessons learnt by research teams. We compared PPI plans extracted from clinical trial grant applications (funded by the National Institute for Health Research Health Technology Assessment Programme between 2006 and 2010) with researchers' and PPI contributors' interview accounts of PPI implementation. Analysis of PPI plans and transcribed qualitative interviews drew on the Framework technique. Of 28 trials, 25 documented plans for PPI in funding applications and half described implementing PPI before applying for funding. Plans varied from minimal to extensive, although almost all anticipated multiple modes of PPI. Interview accounts indicated that PPI plans had been fully implemented in 20/25 trials and even expanded in some. Nevertheless, some researchers described PPI within their trials as tokenistic. Researchers and contributors noted that late or minimal PPI engagement diminished its value. Both groups perceived uncertainty about roles in relation to PPI, and noted contributors' lack of confidence and difficulties attending meetings. PPI contributors experienced problems in interacting with researchers and understanding technical language. Researchers reported difficulties finding 'the right' PPI contributors, and advised caution when involving investigators' current patients. Engaging PPI contributors early and ensuring ongoing clarity about their activities, roles and goals, is crucial to PPI's success. Funders, reviewers and regulators should recognise the value of preapplication PPI and allocate further resources to it. They should also consider whether PPI plans in grant applications match a trial's distinct needs. Monitoring and reporting PPI before, during and after trials will help the

  9. Field sampling and analysis plan for the remedial investigation of Waste Area Grouping 2 at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Boston, H.L.; Ashwood, T.L.; Borders, D.M.; Chidambariah, V.; Downing, D.J.; Fontaine, T.A.; Ketelle, R.H.; Lee, S.Y.; Miller, D.E.; Moore, G.K.; Suter, G.W.; Tardiff, M.F.; Watts, J.A.; Wickliff, D.S.

    1992-02-01

    This field sampling and analysis (S & A) plan has been developed as part of the Department of Energy`s (DOE`s) remedial investigation (RI) of Waste Area Grouping (WAG) 2 at Oak Ridge National Laboratory (ORNL) located in Oak Ridge, Tennessee. The S & A plan has been written in support of the remedial investigation (RI) plan for WAG 2 (ORNL 1990). WAG 2 consists of White Oak Creek (WOC) and its tributaries downstream of the ORNL main plant area, White Oak Lake (WOL), White Oak Creek embayment (WOCE) on the Clinch River, and the associated floodplain and subsurface environment (Fig. 1.1). The WOC system is the surface drainage for the major ORNL WAGs and has been exposed to a diversity of contaminants from operations and waste disposal activities in the WOC watershed. WAG 2 acts as a conduit through which hydrologic fluxes carry contaminants from upgradient areas to the Clinch River. Water, sediment, soil, and biota in WAG 2 are contaminated and continue to receive contaminants from upgradient WAGs. This document describes the following: an overview of the RI plan, background information for the WAG 2 system, and objectives of the S & A plan; the scope and implementation of the first 2 years of effort of the S & A plan and includes recent information about contaminants of concern, organization of S & A activities, interactions with other programs, and quality assurance specific to the S & A activities; provides details of the field sampling plans for sediment, surface water, groundwater, and biota, respectively; and describes the sample tracking and records management plan.

  10. Analysis of drugs in plasma samples from schizophrenic patients by column-switching liquid chromatography-tandem mass spectrometry with organic-inorganic hybrid cyanopropyl monolithic column.

    Science.gov (United States)

    Domingues, Diego Soares; Souza, Israel Donizeti de; Queiroz, Maria Eugênia Costa

    2015-07-01

    This study reports on the development of a rapid, selective, and sensitive column-switching liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze sixteen drugs (antidepressants, anticonvulsants, anxiolytics, and antipsychotics) in plasma samples from schizophrenic patients. The developed organic-inorganic hybrid monolithic column with cyanopropyl groups was used for the first dimension of the column-switching arrangement. This arrangement enabled online pre-concentration of the drugs (monolithic column) and their subsequent analytical separation on an XSelect SCH C18 column. The drugs were detected on a triple quadrupole tandem mass spectrometer (multiple reactions monitoring mode) with an electrospray ionization source in the positive ion mode. The developed method afforded adequate linearity for the sixteen target drugs; the coefficients of determination (R(2)) lay above 0.9932, the interassay precision had coefficients of variation lower than 6.5%, and the relative standard error values of the accuracy ranged from -14.0 to 11.8%. The lower limits of quantification in plasma samples ranged from 63 to 1250pgmL(-1). The developed method successfully analyzed the target drugs in plasma samples from schizophrenic patients for therapeutic drug monitoring (TDM).

  11. Solid phase extraction-capillary electrophoresis determination of sulphonamide residues in milk samples by use of C18-carbon nanotubes as hybrid sorbent materials.

    Science.gov (United States)

    Polo-Luque, M L; Simonet, B M; Valcárcel, M

    2013-07-07

    The exceptional sorption capabilities of carbon nanotubes were used to preconcentrate trace sulphonamides from milk samples. To this end, single walled carbon nanotubes (SWNTs) and multi-walled carbon nanotubes (MWNTs) dispersed in the ionic liquid 1-hexyl-3-methylimidazolium hexafluorophosphate were retained on a C18 stationary phase to obtain a hybrid material in a simple manner. In this approach ionic liquids are an excellent alternative to improve the dispersion of CNTs, without chemical modification or the use of solid substances or organic solvents. MWNTs provided better results than SWNTs. Carbon nanotubes retained in the C18 sorbent matrix were found to confer aromatic character, increasing its preconcentration capacity as a result. The conventional C18 stationary phase played a two-fold role: as a support to retain carbon nanotubes in the cartridge and as a medium to prevent their aggregation. The modified MWNT/C18 and SWNT/C18 materials were used to preconcentrate residual sulphonamides (SAs) in milk samples for their determination at concentrations as low as 0.03-0.069 mg L(-1) by capillary electrophoresis. Analyte recoveries from spiked samples ranged from 103.2 to 98.8% and precision, as RSD, from 8.2 to 5.4%.

  12. Fluorescent in situ hybridization as a tool to retrospectively identify Cryptosporidium parvum and Giardia lamblia in samples from terrestrial mammalian wildlife.

    Science.gov (United States)

    Bednarska, Malgorzata; Bajer, Anna; Sinski, Edward; Girouard, Autumn S; Tamang, Leena; Graczyk, Thaddeus K

    2007-02-01

    Fecal samples of five terrestrial mammalian wildlife species stored at 4 degrees C or at -20 degrees C for up to 36 months have been tested for human zoonotic enteric parasites (i.e., Cryptosporidium parvum and Giardia lamblia) using combined fluorescent in situ hybridization (FISH) and direct fluorescent antibody techniques. The prevalence of C. parvum and G. lamblia varied from 20 to 63% (mean, 45.8%) and from 13 to 100% (mean, 53.2%), respectively. The prevalence of C. parvum and G. lamblia infections was higher in small rodents (mean, 68.5%) than in other wildlife (mean, 21%). Overall, 31.1% of animals were coinfected, and coinfections were more prevalent in small rodents (mean, 52%) than in other wildlife species (mean, 13.2%). The present study has shown that the FISH assay can be retrospectively applied to fecal samples for the identification of C. parvum oocysts, but is less suitable for the identification of G. lamblia cysts in such samples. Terrestrial mammalian wildlife, particularly small rodents, can contribute to watershed contamination with C. parvum oocysts and G. lamblia cysts. To control contamination, the management of pristine watersheds used for drinking water purposes should incorporate control measures for terrestrial wildlife, especially field rodents residing within such watersheds.

  13. Euromet-A Programme for the Collection of New Extraterrestrial Samples: Progress, Plans, or Pipe-Dreams?

    Science.gov (United States)

    Pillinger, C. T.

    1992-07-01

    EUROMET came into being in the wake of the Meteoritical Society Conference held in Vienna in 1989. It is now funded by the European Community Science Programme (Contract No. SC1* - CT91- 0618 (SSMA)) until November 1993, to collect and curate new meteorites and cosmic dust and distribute samples of the material on a worldwide basis. Although the progress towards fully operational status may seem slow, a great many people have contributed substantial amounts of time and effort to establishing a many-faceted project. EUROMET has held three very successful field expeditions to the Frontier Mountains (courtesy of the Italian Progetto Antartide), Dumont d'Urville together with Expeditions Polaires Francaises; Terres Australes et Antarctiques Francaises, and to the Nullarbor Plain (in conjunction with Dr. Alex Bevan, Western Australian Museum WAMET). The curatorial responsibilities extend to over 900 meteorite specimens and in excess of 10,000 cosmic dust grains. More information about these collections is provided elsewhere (several abstracts, this volume) with future updates to be published in the Meteoritical Bulletin. An electronic newsletter will be coming on line for rapid dissemination of information concerning sample characterisation and availability. Information regarding submission of sample requests can be found published in Meteoritics 27, 110 (1992). The EUROMET Council is actively pursuing a number of possibilities to ensure a long-term commitment to meteorite and micrometeorite recovery. Although many of the plans are still tentative they are moving towards fruition. Future Antarctic activities will hopefully include a 1992/3 mission to Frontier Mountains and other locations in Victoria Land and a more sophisticated cosmic dust factory (1994/5) with sponsors as before. Additionally we are exploring the possibility of a joint EUROMET/Indian expedition to Wohlthat Massif, which will be followed up via the German Georg Forster base in conjunction with Ganovex

  14. The uncertainty of atmospheric processes in planning a hybrid renewable energy system for a non-connected island

    Science.gov (United States)

    Daniil, Vasiliki; Pouliasis, George; Zacharopoulou, Eleni; Demetriou, Evangelos; Manou, Georgia; Chalakatevaki, Maria; Parara, Iliana; Georganta, Xristina; Stamou, Paraskevi; Karali, Sophia; Hadjimitsis, Evanthis; Koudouris, Giannis; Moschos, Evangelos; Roussis, Dimitrios; Papoulakos, Konstantinos; Koskinas, Aristotelis; Pollakis, Giorgos; Gournari, Panagiota; Sakellari, Katerina; Moustakis, Yiannis

    2017-04-01

    Non-connected islands to the electric gird are often depending on oil-fueled power plants with high unit cost. A hybrid energy system with renewable resources such as wind and solar plants could reduce this cost and also offer more environmental friendly solutions. However, atmospheric processes are characterized by high uncertainty that does not permit harvesting and utilizing full of their potential. Therefore, a more sophisticated framework that somehow incorporates this uncertainty could improve the performance of the system. In this context, we describe several stochastic and financial aspects of this framework. Particularly, we investigate the cross-correlation between several atmospheric processes and the energy demand, the possibility of mixing renewable resources with the conventional ones and in what degree of reliability, and critical financial subsystems such as weather derivatives. A pilot application of the above framework is also presented for a remote island in the Aegean Sea. Acknowledgement: This research is conducted within the frame of the undergraduate course "Stochastic Methods in Water Resources" of the National Technical University of Athens (NTUA). The School of Civil Engineering of NTUA provided moral support for the participation of the students in the Assembly. *The "Stochastics in Energy Resources Management (NTUA)" Team: Nikos Mamasis, Andreas Efstratiadis, Hristos Tyralis, Panayiotis Dimitriadis, Theano Iliopoulou, Georgios Karakatsanis, Katerina Tzouka, Ilias Deligiannis, Vicky Tsoukala, Panos Papanicolaou and Demetris Koutsoyiannis

  15. Magnetic Fields of Be Stars: Preliminary Results from a Hybrid Analysis of the MiMeS Sample

    Science.gov (United States)

    Wade, G. A.; Petit, V.; Grunhut, J. H.; Neiner, C.; MiMeS Collaboration

    2016-11-01

    In the context of the MiMeS survey of magnetism in massive stars, 85 classical Be stars were observed in circular polarization with the aim of detecting magnetic fields at their surfaces. No direct evidence of such fields is found, in contrast to the significant rate of detection (5-10%) in non-Be B-type stars. In this paper we describe the sample properties, the methodology and the data quality. We describe a novel method, previously applied to Herbig Ae/Be stars, that allows us to infer upper limits on organized (dipolar) magnetic fields present in the photospheres of our targets. We review the characteristics and robustness of this null result, and discuss its implications.

  16. Oral health workforce planning part 2: figures, determinants and trends in a sample of World Dental Federation member countries.

    Science.gov (United States)

    Yamalik, Nermin; Ensaldo-Carrasco, Eduardo; Cavalle, Edoardo; Kell, Kathyrn

    2014-06-01

    A range of factors needs to be taken into account for an ideal oral health workforce plan. The figures related to dentists, specialists, auxiliaries, practice patterns, undergraduate and continuing dental education, laws/regulations, the attitudes of oral health-care providers and the general trends affecting the practice patterns, work conditions and preferences of oral health-care providers are among such determinants. Thus, the aim of the present study was to gather such information from a sample of World Dental Federation (FDI) member countries with different characteristics. A cross-sectional survey study was carried out among a sample of FDI member countries between March 2, 2012 and March 27, 2012. A questionnaire was developed addressing some main determinants of oral health workforce, such as its structure, involvement of the public/private sector to provide oral health-care services, specialty services, dental schools, trends in workforce and compliance with oral health needs, and a descriptive analysis was performed. The countries were classified as developed and developing countries and Mann-Whitney U-tests and chi-square tests were used to identify potential significant differences (P > 0.05) between developed and developing countries. All data were processed in SPSS v.19. In the18 questionnaires processed, the median number of dentists (P = 0.005), dental practices (P = 0.002), hygienists (P = 0.005), technicians (P = 0.013) and graduates per year (P = 0.037) was higher in developed countries. Only 12.5% of developed and 22.2% of developing countries reported having optimal number of graduates per year. It was noted that 66.7% of developing countries had more regions lacking enough dentists to meet the demand (P = 0.050) and 77.8% lacked the necessary specialist care (P = 0.015). Although developing countries reported mostly an oversupply of dentists, regardless of the level of development most countries did not report an oversupply of specialists

  17. Selection of the treatment effect for sample size determination in a superiority clinical trial using a hybrid classical and Bayesian procedure.

    Science.gov (United States)

    Ciarleglio, Maria M; Arendt, Christopher D; Makuch, Robert W; Peduzzi, Peter N

    2015-03-01

    Specification of the treatment effect that a clinical trial is designed to detect (θA) plays a critical role in sample size and power calculations. However, no formal method exists for using prior information to guide the choice of θA. This paper presents a hybrid classical and Bayesian procedure for choosing an estimate of the treatment effect to be detected in a clinical trial that formally integrates prior information into this aspect of trial design. The value of θA is found that equates the pre-specified frequentist power and the conditional expected power of the trial. The conditional expected power averages the traditional frequentist power curve using the conditional prior distribution of the true unknown treatment effect θ as the averaging weight. The Bayesian prior distribution summarizes current knowledge of both the magnitude of the treatment effect and the strength of the prior information through the assumed spread of the distribution. By using a hybrid classical and Bayesian approach, we are able to formally integrate prior information on the uncertainty and variability of the treatment effect into the design of the study, mitigating the risk that the power calculation will be overly optimistic while maintaining a frequentist framework for the final analysis. The value of θA found using this method may be written as a function of the prior mean μ0 and standard deviation τ0, with a unique relationship for a given ratio of μ0/τ0. Results are presented for Normal, Uniform, and Gamma priors for θ.

  18. Seeps and springs sampling and analysis plant for the Environmental Monitoring Plan at Waste Area Grouping 6, Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This Sampling and Analysis Plan addresses the monitoring, sampling, and analysis activities that will be conducted at seeps and springs and at two french drain outlets in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-land-burial disposal facility for low-level radioactive waste at Oak Ridge National Laboratory, a research facility owned by the U.S. Department of Energy and operated by Lockheed Martin Energy System, Inc. Initially, sampling will be conducted at as many as 15 locations within WAG 6 (as many as 13 seeps and 2 french drain outlets). After evaluating the results obtained and reviewing the observations made by field personnel during the first round of sampling, several seeps and springs will be chosen as permanent monitoring points, together with the two french drain outlets. Baseline sampling of these points will then be conducted quarterly for 1 year (i.e., four rounds of sampling after the initial round). The samples will be analyzed for various geochemical, organic, inorganic, and radiological parameters. Permanent sampling points having suitable flow rates and conditions may be outfitted with automatic flow-monitoring equipment. The results of the sampling and flow-monitoring efforts will help to quantify flux moving across the ungauged perimeter of the site and will help to identify changes in releases from the contaminant sources.

  19. Proposed draft aflatoxin sampling plans for aflatoxin contamination oin ready-to-eat treenuts and treenuts destined for futher procession: almonds, hazelnuts, pistachio, and brazil nuts

    Science.gov (United States)

    1. Importers may commercially classify treenuts as either “ready-to-eat” (RTE) or “destined for further processing” (DFP). As a result, maximum levels and sampling plans are proposed for both commercial types of treenuts. Maximum levels need to be defined for treenuts destined for further processing...

  20. A Test of the Theory of Planned Behavior to Predict Physical Activity in an Overweight/Obese Population Sample of Adolescents from Alberta, Canada

    Science.gov (United States)

    Plotnikoff, Ronald C.; Lubans, David R.; Costigan, Sarah A.; McCargar, Linda

    2013-01-01

    Purpose: To examine the utility of the theory of planned behavior (TPB) for explaining physical activity (PA) intention and behavior among a large population sample of overweight and obese adolescents (Alberta, Canada), using a web-based survey. Secondary objectives were to examine the mediating effects of the TPB constructs and moderating effects…

  1. From Planning to Implementation: An Examination of Changes in the Research Design, Sample Size, and Precision of Group Randomized Trials Launched by the Institute of Education Sciences

    Science.gov (United States)

    Spybrook, Jessaca; Puente, Anne Cullen; Lininger, Monica

    2013-01-01

    This article examines changes in the research design, sample size, and precision between the planning phase and implementation phase of group randomized trials (GRTs) funded by the Institute of Education Sciences. Thirty-eight GRTs funded between 2002 and 2006 were examined. Three studies revealed changes in the experimental design. Ten studies…

  2. A Test of the Theory of Planned Behavior to Predict Physical Activity in an Overweight/Obese Population Sample of Adolescents from Alberta, Canada

    Science.gov (United States)

    Plotnikoff, Ronald C.; Lubans, David R.; Costigan, Sarah A.; McCargar, Linda

    2013-01-01

    Purpose: To examine the utility of the theory of planned behavior (TPB) for explaining physical activity (PA) intention and behavior among a large population sample of overweight and obese adolescents (Alberta, Canada), using a web-based survey. Secondary objectives were to examine the mediating effects of the TPB constructs and moderating effects…

  3. A novel derivation of a within-batch sampling plan based on a Poisson-gamma model characterising low microbial counts in foods

    NARCIS (Netherlands)

    Gonzalez-Barron, U.; Zwietering, M.H.; Butler, F.

    2013-01-01

    This study proposes a novel step-wise methodology for the derivation of a sampling plan by variables for food production systems characterised by relatively low concentrations of the inspected microorganism. After representing the universe of contaminated batches by modelling the between-batch and w

  4. Ultrasensitive photoelectrochemical determination of chromium(VI) in water samples by ion-imprinted/formate anion-incorporated graphitic carbon nitride nanostructured hybrid.

    Science.gov (United States)

    Fang, Tian; Yang, Xiaomin; Zhang, Lizhi; Gong, Jingming

    2016-07-15

    A rapid and highly sensitive photoelectrochemical (PEC) method has been proposed for the determination of trace amounts of chromium in water samples under visible-light irradiation. Here, a unique nanostructured hybrid of formate anion incorporated graphitic carbon nitride (F-g-C3N4) is smartly integrated with a Cr(VI) ion-imprinted polymer (IIP) as a photoactive electrode (denoted as IIP@F-g-C3N4). The nanohybrid of F-g-C3N4 exhibits an enhanced charge separation with substantially improved PEC responses versus g-C3N4. The newly designed IIP@F-g-C3N4 PEC sensor exhibits high sensitivity and selectivity for the determination of Cr(VI) because it offers efficient photogenerated electron reduction toward Cr(VI). The PEC analysis is highly linear over Cr(VI) concentrations ranging from 0.01 to 100.00ppb with a detection limit of 0.006ppb (S/N=3). Our approach can be used to detect Cr(VI), Cr(III) and the total chromium level in aqueous solution through oxidation of Cr(III) to Cr(VI) and the determination of the total chromium as Cr(VI). In practical applications, this low-cost and sensitive assay has been successfully applied for speciation determination of chromium in environmental water samples. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. A novel derivation of a within-batch sampling plan based on a Poisson-gamma model characterising low microbial counts in foods.

    Science.gov (United States)

    Gonzales-Barron, Ursula; Zwietering, Marcel H; Butler, Francis

    2013-02-01

    This study proposes a novel step-wise methodology for the derivation of a sampling plan by variables for food production systems characterised by relatively low concentrations of the inspected microorganism. After representing the universe of contaminated batches by modelling the between-batch and within-batch variability in microbial counts, a tolerance criterion defining batch acceptability (i.e., up to a tolerance percentage of the food units having microbial concentrations lower or equal to a critical concentration) is established to delineate a limiting quality contour that separates satisfactory from unsatisfactory batches. The problem consists then of finding the optimum decision criterion - arithmetic mean of the analytical results (microbiological limit, m(L)) and the sample size (n) - that satisfies a pre-defined level of confidence measured on the samples' mean distributions from all possible true within-batch distributions. This is approached by obtaining decision landscape curves representing collectively the conditional and joint producer's and consumer's risks at different microbiological limits along with confidence intervals representing uncertainty due to the propagated between-batch variability. Whilst the method requires a number of risk management decisions to be made such as the objective of the sampling plan (GMP-based or risk-based), the modality of derivation, the tolerance criterion or level of safety, and the statistical level of confidence, the proposed method can be used when past monitoring data are available so as to produce statistically-sound dynamic sampling plans with optimised efficiency and discriminatory power. For the illustration of Enterobacteriaceae concentrations on Irish sheep carcasses, a sampling regime of n=10 and m(L)=17.5CFU/cm(2) is recommended to ensure that the producer has at least a 90% confidence of accepting a satisfactory batch whilst the consumer at least a 97.5% confidence that a batch will not be

  6. Hybrid propulsion technology program

    Science.gov (United States)

    1990-01-01

    Technology was identified which will enable application of hybrid propulsion to manned and unmanned space launch vehicles. Two design concepts are proposed. The first is a hybrid propulsion system using the classical method of regression (classical hybrid) resulting from the flow of oxidizer across a fuel grain surface. The second system uses a self-sustaining gas generator (gas generator hybrid) to produce a fuel rich exhaust that was mixed with oxidizer in a separate combustor. Both systems offer cost and reliability improvement over the existing solid rocket booster and proposed liquid boosters. The designs were evaluated using life cycle cost and reliability. The program consisted of: (1) identification and evaluation of candidate oxidizers and fuels; (2) preliminary evaluation of booster design concepts; (3) preparation of a detailed point design including life cycle costs and reliability analyses; (4) identification of those hybrid specific technologies needing improvement; and (5) preperation of a technology acquisition plan and large scale demonstration plan.

  7. Planning the sampling of a condensed-gas field with an oil fringe at the Benoi field

    Energy Technology Data Exchange (ETDEWEB)

    Siuniaev, Y.K.; Trubaev, V.L.

    1981-01-01

    In order to obtain data for determining gas, condensate and oil reserves, planning field development, and monitoring the operation of condensed gas wells in fields, a system of gas-hydrodynamic and specialized studies is developed.

  8. Planned missing-data designs in experience-sampling research: Monte Carlo simulations of efficient designs for assessing within-person constructs.

    Science.gov (United States)

    Silvia, Paul J; Kwapil, Thomas R; Walsh, Molly A; Myin-Germeys, Inez

    2014-03-01

    Experience-sampling research involves trade-offs between the number of questions asked per signal, the number of signals per day, and the number of days. By combining planned missing-data designs and multilevel latent variable modeling, we show how to reduce the items per signal without reducing the number of items. After illustrating different designs using real data, we present two Monte Carlo studies that explored the performance of planned missing-data designs across different within-person and between-person sample sizes and across different patterns of response rates. The missing-data designs yielded unbiased parameter estimates but slightly higher standard errors. With realistic sample sizes, even designs with extensive missingness performed well, so these methods are promising additions to an experience-sampler's toolbox.

  9. Meal planning is associated with food variety, diet quality and body weight status in a large sample of French adults.

    Science.gov (United States)

    Ducrot, Pauline; Méjean, Caroline; Aroumougame, Vani; Ibanez, Gladys; Allès, Benjamin; Kesse-Guyot, Emmanuelle; Hercberg, Serge; Péneau, Sandrine

    2017-02-02

    Meal planning could be a potential tool to offset time scarcity and therefore encourage home meal preparation, which has been linked with an improved diet quality. However, to date, meal planning has received little attention in the scientific literature. The aim of our cross-sectional study was to investigate the association between meal planning and diet quality, including adherence to nutritional guidelines and food variety, as well as weight status. Meal planning, i.e. planning ahead the foods that will be eaten for the next few days, was assessed in 40,554 participants of the web-based observational NutriNet-Santé study. Dietary measurements included intakes of energy, nutrients, food groups, and adherence to the French nutritional guidelines (mPNNS-GS) estimated through repeated 24-h dietary records. A food variety score was also calculated using Food Frequency Questionnaire. Weight and height were self-reported. Association between meal planning and dietary intakes were assessed using ANCOVAs, while associations with quartiles of mPNNS-GS scores, quartiles of food variety score and weight status categories (overweight, obesity) were evaluated using logistic regression models. A total of 57% of the participants declared to plan meals at least occasionally. Meal planners were more likely to have a higher mPNNS-GS (OR quartile 4 vs. 1 = 1.13, 95% CI: [1.07-1.20]), higher overall food variety (OR quartile 4 vs. 1 = 1.25, 95% CI: [1.18-1.32]). In women, meal planning was associated with lower odds of being overweight (OR = 0.92 [0.87-0.98]) and obese (OR = 0.79 [0.73-0.86]). In men, the association was significant for obesity only (OR = 0.81 [0.69-0.94]). Meal planning was associated with a healthier diet and less obesity. Although no causality can be inferred from the reported associations, these data suggest that meal planning could potentially be relevant for obesity prevention.

  10. Plan for proposed aquifer hydraulic testing and groundwater sampling at Everest, Kansas, in January-February 2006.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2006-01-31

    well and subsequent testing of a new well to be installed north-northeast of the Nigh well. On November 28, 2005, the KDHE provided written comments on the Cross Section Analysis and the recommendations outlined above. In response to the KDHE's comments, the CCC/USDA agreed (Roe 2005) to discontinue plans to test the Nigh well. The CCC/USDA agreed to proceed instead with the design and installation of a new pumping well and associated observation points to be used for pump testing of the Everest aquifer along the apparent contaminant migration pathway north-northeast of the Nigh property. In conjunction with this test, the CCC/USDA also proposed groundwater sampling with the cone penetrometer (CPT) at the possible monitoring well locations requested by the KDHE in lieu of installing permanent monitoring points.

  11. 需求不确定下炼油企业生产计划优化混合规划模型%A Hybrid Programming Model for Optimal Production Planning under Demand Uncertainty in Refinery

    Institute of Scientific and Technical Information of China (English)

    李初福; 何小荣; 陈丙珍; 徐强; 刘朝玮

    2008-01-01

    Production planning under uncertainty is considered as one of the most important problems in plant-wide optimization. In this article, first, a stochastic programming model with uniform distribution assumption is developed for refinery production planning under demand uncertainty, and then a hybrid programming model in-corporating the linear programming model with the stochastic programming one by a weight factor is proposed. Subsequently, piecewise linear approximation functions are derived and applied to solve the hybrid programming model under uniform distribution assumption. Case studies show that the linear approximation algorithm is effec-tive to solve the hybrid programming model, along with an error≤0.5% when the deviation/mean≤20%. The simulation results indicate that the hybrid programming model with an appropriate weight factor (0.1-0.2) can ef-fectively improve the optimal operational strategies under demand uncertainty, achieving higher profit than the lin-ear programming model and the stochastic programming one with about 1.5% and 0.4% enhancement, respectively.

  12. Diagnosis of anaplastic lymphoma kinase rearrangement in cytological samples through a fluorescence in situ hybridization-based assay: Cytological smears versus cell blocks.

    Science.gov (United States)

    Zito Marino, Federica; Rossi, Giulio; Brunelli, Matteo; Malzone, Maria Gabriella; Liguori, Giuseppina; Bogina, Giuseppe; Morabito, Alessandro; Rocco, Gaetano; Franco, Renato; Botti, Gerardo

    2017-05-01

    Anaplastic lymphoma kinase (ALK) status analysis of lung cytological specimens should be successfully encouraged in routine practice because biopsy specimens are not always available. To date, the US Food and Drug Administration has approved both fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) as diagnostic tests for identifying ALK-positive patients eligible for treatment with crizotinib. Although ALK IHC is an optimal diagnostic tool, FISH becomes mandatory in equivocal cases. ALK FISH of paraffin-embedded tissue material is still the gold standard, whereas the cytological specimen assay has not yet been completely standardized. Many controversial data have been reported on the adequacy of cytology cell blocks (CBs) versus conventional smears for FISH testing. This review discusses some critical issues related to ALK FISH of cytological samples, including the triaging of collected specimens to optimize the material, the use of CBs versus conventional smears, and alternative methods for an ALK rearrangement diagnosis. Conventional smears have the advantages of an immediate evaluation, no probe tissue-related artifactual loss, no fixation-related alterations, and usually sufficient material for an analytic preparation. On the other hand, CBs have several advantages, including the appropriate conservation of the tissue architecture, an absence of problems related to cell overlapping, and the ability to evaluate neoplastic cells in a dark field. Cancer Cytopathol 2017;125:303-312. © 2017 American Cancer Society. © 2017 American Cancer Society.

  13. Incorporating genetic sampling in long-term monitoring and adaptive management in the San Diego County Management Strategic Plan Area, Southern California

    Science.gov (United States)

    Vandergast, Amy G.

    2017-06-02

    Habitat and species conservation plans usually rely on monitoring to assess progress towards conservation goals. Southern California, USA, is a hotspot of biodiversity and home to many federally endangered and threatened species. Here, several regional multi-species conservation plans have been implemented to balance development and conservation goals, including in San Diego County. In the San Diego County Management Strategic Plan Area (MSPA), a monitoring framework for the preserve system has been developed with a focus on species monitoring, vegetation monitoring, threats monitoring and abiotic monitoring. Genetic sampling over time (genetic monitoring) has proven useful in gathering species presence and abundance data and detecting population trends, particularly related to species and threats monitoring objectives. This report reviews genetic concepts and techniques of genetics that relate to monitoring goals and outlines components of a genetic monitoring scheme that could be applied in San Diego or in other monitoring frameworks throughout the Nation.

  14. Surface water sampling and analysis plan for environmental monitoring in Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This Sampling and Analysis Plan addresses surface water monitoring, sampling, and analysis activities that will be conducted in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-burial land disposal facility for low-level radioactive waste at the Oak Ridge National Laboratory, a research facility owned by the US Department of Energy and managed by Martin Marietta Energy Systems, Inc. Surface water monitoring will be conducted at nine sites within WAG 6. Activities to be conducted will include the installation, inspection, and maintenance of automatic flow-monitoring and sampling equipment and manual collection of various water and sediment samples. The samples will be analyzed for various organic, inorganic, and radiological parameters. The information derived from the surface water monitoring, sampling, and analysis will aid in evaluating risk associated with contaminants migrating off-WAG, and will be used in calculations to establish relationships between contaminant concentration (C) and flow (Q). The C-Q relationship will be used in calculating the cumulative risk associated with the off-WAG migration of contaminants.

  15. Synthesis of new hybrid sorbent by grafting 2,6-diacetyl pyridine onto microporous β-zeolite and its application in solid phase extraction of heavy metals from environmental samples

    Indian Academy of Sciences (India)

    HARINATH YAPATI; SREENU BHOGINENI; SURESH CHIRUMAMILLA; K SESHAIAH

    2016-05-01

    The aim of this study was synthesis of a new hybrid material and its application in solid phaseextraction of metal ions from environmental samples. The hybrid material was synthesized by grafting3-aminopropyl trimethoxy silane onto Β-zeolite and functionalizing with 2,6-diacetyl pyridine in a stepwise covalentprocess. This hybrid material was characterized by FT-IR and XRD studies. The hybrid material was usedas sorbent in solid phase extraction of Pb(II), Ni(II), Cu(II) and Cd(II). The method is based on the collectionof metal ions onto 2,6-DAP-PA-Β-zeolite and the sorbed metal ions were eluted with 10mL of 1M $HNO_{3}.The influences of analytical parameters such as pH of the sample solution, volume of sample, type and volumeof eluent, flow rate of the sample and eluent that govern the efficiency and throughput of the method wereevaluated. The influence effects of matrix ions (common ions other than the analyte that are present in the sample)on the retentions of the metal ions were also examined. The maximum adsorption capacity values for themetal ions onto 2,6-DAP-PA-Β-zeolite, as calculated from the Langmuir model, were 112.7, 94.2, 105, and102.8mg $g^{-1}$ respectively. The relative standard deviation under optimum conditions was lower than 3.10%.The limits of detection were 0.035 for Pb(II), 0.076 for Ni(II), 0.083 for Cu(II) and 0.059 mg $L^{-1}$ for Cd(II),respectively. The accuracy of the method was estimated by analyzing reference standard materials. The resultsindicate that the method is efficient for the solid phase extraction of trace levels of Pb(II), Ni(II), Cu(II) andCd(II) from environmental samples.

  16. Metal-organic framework-199/graphite oxide hybrid composites coated solid-phase microextraction fibers coupled with gas chromatography for determination of organochlorine pesticides from complicated samples.

    Science.gov (United States)

    Zhang, Suling; Du, Zhuo; Li, Gongke

    2013-10-15

    The hybrid material of a copper-based metal-organic framework (MOF-199) and graphite oxide (GO) was explored as the solid-phase microextraction (SPME) coating for the first time. This fiber was fabricated by using 3-amino-propyltriethoxysilane (APTES) as the cross-linking agent, which enhanced its durability and allowed more than 140 replicate extractions. With the incorporation of GO, the MOF-199/GO fibers with GO contents ranging from 5 to 15 wt% exhibited enhanced adsorption affinity to organochlorine pesticides (OCPs) compared to MOF or GO individually. This improvement was linked to the enhanced dispersive forces (increased volume of small pores) that provided by the dense carbon layers of GO. Combining the superior properties of high porosity of MOFs and the unique layered character of GO, the MOF-199/GO (10 wt%) fiber exhibited higher adsorption affinity to some OCPs than commercial polydimethylsiloxane (PDMS) and polydimethylsiloxane/divinylbenzene (PDMS/DVB) fibers. This new fiber was developed for headspace (HS) SPME of eight OCPs followed by GC/ECD analysis. The limits of detection were 2.3-6.9 ng/L. The relative standard deviation (RSD) for five replicate extractions using one fiber ranged from 5.3% to 8.8%. The fiber-to-fiber reproducibility was 5.2-12.8%. This method was successfully used for simultaneous determination of eight OCPs from river water, soil, water convolvulus and longan with satisfactory recoveries of 90.6-104.4%, 82.7-96.8%, 72.2-107.7% and 82.8-94.3%, respectively. These results indicated the MOF-199/GO composite provided a promising alternative in sample pretreatment.

  17. Branched-Chain in situ Hybridization for κ and λ Light Chains: A Powerful Ancillary Technique for Determining B-Cell Clonality in Cytology Samples

    Science.gov (United States)

    Arora, Kshitij; Chebib, Ivan; Zukerberg, Lawrence; Gandhi, Manoj; Rivera, Miguel; Ting, David; Deshpande, Vikram

    2017-01-01

    BACKGROUND Current immunohistochemical and in situ hybridization (ISH) assays are generally inconclusive for clonality unless plasmacytic differentiation is present. This study examined a series of cytology specimens and explored the ability of a branched-chain RNA (bRNA) ISH assay for immunoglobulin κ constant (IGKC) and immunoglobulin λ constant (IGLC) to detect a clonal population of B lymphocytes. METHODS Pathology databases were used to identify fine-needle aspiration biopsies (n = 28) and exfoliative cytology samples (n = 20). Demographic, flow cytometry, and excision biopsy results were recorded. bRNA ISH was performed on the Leica Bond platform with the following probes: IGKC, IGLC, immunoglobulin λ-like polypeptide 5 (IGLL5), and a housekeeping gene (HKG). RESULTS The bRNA ISH assay was validated with 30 surgical biopsies. On bRNA ISH, a clonal B-cell population (light-chain ratio > 10:1) was detected in 22 of 28 cases with a final diagnosis of lymphoma. In 2 cases, a κ predominance was present, although the ratio was <10:1. Eleven of the 17 κ-clonal lymphomas also expressed IGLL5, the latter recognized by the presence of an intranuclear signal. Two B-cell lymphomas lacked IGKC and IGLC, whereas 2 cases were negative for the HKG. In 12 of the 20 cases with reactive lymphoid tissue, bRNA ISH identified a polyclonal lymphoid population. No light-chain messenger RNA was detected in 6 cases (typically those associated with very few B cells). CONCLUSIONS The automated bRNA ISH platform is a robust technique for detecting a clonal B-cell population in cytology material. PMID:26524200

  18. The U.S. Geological Survey Geologic Collections Management System (GCMS)—A master catalog and collections management plan for U.S. Geological Survey geologic samples and sample collections

    Science.gov (United States)

    ,

    2015-01-01

    The U.S. Geological Survey (USGS) is widely recognized in the earth science community as possessing extensive collections of earth materials collected by research personnel over the course of its history. In 2006, a Geologic Collections Inventory was conducted within the USGS Geology Discipline to determine the extent and nature of its sample collections, and in 2008, a working group was convened by the USGS National Geologic and Geophysical Data Preservation Program to examine ways in which these collections could be coordinated, cataloged, and made available to researchers both inside and outside the USGS. The charge to this working group was to evaluate the proposition of creating a Geologic Collections Management System (GCMS), a centralized database that would (1) identify all existing USGS geologic collections, regardless of size, (2) create a virtual link among the collections, and (3) provide a way for scientists and other researchers to obtain access to the samples and data in which they are interested. Additionally, the group was instructed to develop criteria for evaluating current collections and to establish an operating plan and set of standard practices for handling, identifying, and managing future sample collections. Policies and procedures promoted by the GCMS would be based on extant best practices established by the National Science Foundation and the Smithsonian Institution. The resulting report—USGS Circular 1410, “The U.S. Geological Survey Geologic Collections Management System (GCMS): A Master Catalog and Collections Management Plan for U.S. Geological Survey Geologic Samples and Sample Collections”—has been developed for sample repositories to be a guide to establishing common practices in the collection, retention, and disposal of geologic research materials throughout the USGS.

  19. Detection of Human Papillomavirus DNA in Cervical Samples: Analysis of the New PGMY-PCR Compared To the Hybrid Capture II and MY-PCR Assays and a Two-Step Nested PCR Assay

    OpenAIRE

    Giovannelli, Lucia; Lama, Anna; Capra, Giuseppina; Giordano, Viviana; Aricò, Pietro; Ammatuna, Pietro

    2004-01-01

    The PGMY-PCR for human papillomavirus (HPV) was evaluated, in parallel with nested PCR (nPCR), in samples with noted Hybrid Capture II (HCII) and MY-PCR results. PGMY-PCR detected HPV DNA in 2.5% of HCII-negative-MY-PCR-negative samples and in 71.7% of HCII-positive-MY-PCR-negative samples; also, it detected the MY-PCR-negative-nPCR-negative types HPV-42, HPV-44, HPV-51, HPV-87, and HPV-89.

  20. Atlas-guided generation of pseudo-CT images for MRI-only and hybrid PET-MRI-guided radiotherapy treatment planning.

    Science.gov (United States)

    Arabi, Hossein; Koutsouvelis, Nikolaos; Rouzaud, Michel; Miralbell, Raymond; Zaidi, Habib

    2016-09-07

    -only) and atlas-guided AC. Dosimetric evaluation using dose volume histograms and the average difference between minimum/maximum absorbed doses revealed a mean error of less than 1% for the both target volumes and organs at risk. Two-dimensional (2D) gamma analysis of the isocenter dose distributions at 1%/1 mm criterion revealed pass rates of 91.40  ±  7.56%, 96.00  ±  4.11% and 97.67  ±  3.6% for MRI segmentation, atlas-guided and the proposed methods, respectively. The proposed method generates accurate pseudo-CT images from conventional Dixon MRI sequences with improved bone extraction accuracy. The approach is promising for potential use in PET AC and MRI-only or hybrid PET/MRI-guided RT treatment planning.

  1. Atlas-guided generation of pseudo-CT images for MRI-only and hybrid PET-MRI-guided radiotherapy treatment planning

    Science.gov (United States)

    Arabi, Hossein; Koutsouvelis, Nikolaos; Rouzaud, Michel; Miralbell, Raymond; Zaidi, Habib

    2016-09-01

    -only) and atlas-guided AC. Dosimetric evaluation using dose volume histograms and the average difference between minimum/maximum absorbed doses revealed a mean error of less than 1% for the both target volumes and organs at risk. Two-dimensional (2D) gamma analysis of the isocenter dose distributions at 1%/1 mm criterion revealed pass rates of 91.40  ±  7.56%, 96.00  ±  4.11% and 97.67  ±  3.6% for MRI segmentation, atlas-guided and the proposed methods, respectively. The proposed method generates accurate pseudo-CT images from conventional Dixon MRI sequences with improved bone extraction accuracy. The approach is promising for potential use in PET AC and MRI-only or hybrid PET/MRI-guided RT treatment planning.

  2. [Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio]. Volume 3, Sampling and analysis plan (SAP): Phase 1, Task 4, Field Investigation: Draft

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-01

    In April 1990, Wright-Patterson Air Force Base (WPAFB), initiated an investigation to evaluate a potential Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) removal action to prevent, to the extent practicable, the offsite migration of contaminated ground water from WPAFB. WPAFB retained the services of the Environmental Management Operations (EMO) and its principle subcontractor, International Technology Corporation (IT) to complete Phase 1 of the environmental investigation of ground-water contamination at WPAFB. Phase 1 of the investigation involves the short-term evaluation and potential design for a program to remove ground-water contamination that appears to be migrating across the western boundary of Area C, and across the northern boundary of Area B along Springfield Pike. Primarily, Task 4 of Phase 1 focuses on collection of information at the Area C and Springfield Pike boundaries of WPAFB. This Sampling and Analysis Plan (SAP) has been prepared to assist in completion of the Task 4 field investigation and is comprised of the Quality Assurance Project Plan (QAPP) and the Field Sampling Plan (FSP).

  3. Probabilistic Requirements (Partial) Verification Methods Best Practices Improvement. Variables Acceptance Sampling Calculators: Derivations and Verification of Plans. Volume 1

    Science.gov (United States)

    Johnson, Kenneth L.; White, K, Preston, Jr.

    2012-01-01

    The NASA Engineering and Safety Center was requested to improve on the Best Practices document produced for the NESC assessment, Verification of Probabilistic Requirements for the Constellation Program, by giving a recommended procedure for using acceptance sampling by variables techniques. This recommended procedure would be used as an alternative to the potentially resource-intensive acceptance sampling by attributes method given in the document. This document contains the outcome of the assessment.

  4. Y-12 Groundwater Protection Program Groundwater And Surface Water Sampling And Analysis Plan For Calendar Year 2014

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-09-01

    This plan provides a description of the groundwater and surface water quality monitoring activities planned for calendar year (CY) 2014 at the U.S. Department of Energy (DOE) Y-12 National Security Complex (Y-12) that will be managed by the Y-12 Groundwater Protection Program (GWPP). Groundwater and surface water monitoring is performed by the GWPP during CY 2014 to achieve the following goals: 􀁸 to protect the worker, the public, and the environment; 􀁸 to maintain surveillance of existing and potential groundwater contamination sources; 􀁸 to provide for the early detection of groundwater contamination and determine the quality of groundwater and surface water where contaminants are most likely to migrate beyond the Oak Ridge Reservation property line; 􀁸 to identify and characterize long-term trends in groundwater quality at Y-12; and 􀁸 to provide data to support decisions concerning the management and protection of groundwater resources. Groundwater and surface water monitoring will be performed in three hydrogeologic regimes at Y-12.

  5. A Hybrid Architecture Approach for Quantum Algorithms

    Directory of Open Access Journals (Sweden)

    Mohammad R.S. Aghaei

    2009-01-01

    Full Text Available Problem statement: In this study, a general plan of hybrid architecture for quantum algorithms is proposed. Approach: Analysis of the quantum algorithms shows that these algorithms were hybrid with two parts. First, the relationship of classical and quantum parts of the hybrid algorithms was extracted. Then a general plan of hybrid structure was designed. Results: This plan was illustrated the hybrid architecture and the relationship of classical and quantum parts of the algorithms. This general plan was used to increase implementation performance of quantum algorithms. Conclusion/Recommendations: Moreover, simulation results of quantum algorithms on the hybrid architecture proved that quantum algorithms can be implemented on the general plan as well.

  6. Hybrid vehicle potential assessment. Volume 7. Hybrid vehicle review

    Energy Technology Data Exchange (ETDEWEB)

    Leschly, K.O.

    1979-09-30

    Review of hybrid vehicles (HVs) built during the past ten years or planned to be built in the near future is presented. An attempt is made to classify and analyze these vehicles to get an overall picture of their key characteristics. The review includes on-road hybrid passenger cars, trucks, vans, and buses.

  7. Hybrid vehicle potential assessment. Volume 7: Hybrid vehicle review

    Science.gov (United States)

    Leschly, K. O.

    1979-01-01

    Review of hybrid vehicles built during the past ten years or planned to be built in the near future is presented. An attempt is made to classify and analyze these vehicles to get an overall picture of their key characteristics. The review includes onroad hybrid passenger cars, trucks, vans, and buses.

  8. Analysis of Waste Isolation Pilot Plan (WIPP) Underground and MGO Samples by the Savannah River National Laboratory (SRNL)

    Energy Technology Data Exchange (ETDEWEB)

    Young, J. [Savannah River Site (SRS), Aiken, SC (United States); Ajo, H. [Savannah River Site (SRS), Aiken, SC (United States); Brown, L. [Savannah River Site (SRS), Aiken, SC (United States); Coleman, C. [Savannah River Site (SRS), Aiken, SC (United States); Crump, S. [Savannah River Site (SRS), Aiken, SC (United States); Diprete, C. [Savannah River Site (SRS), Aiken, SC (United States); Diprete, D. [Savannah River Site (SRS), Aiken, SC (United States); Ekechukwu, A. [Savannah River Site (SRS), Aiken, SC (United States); Gregory, C. [Savannah River Site (SRS), Aiken, SC (United States); Jones, M. [Savannah River Site (SRS), Aiken, SC (United States); Missimer, D. [Savannah River Site (SRS), Aiken, SC (United States); O' Rourke, P. [Savannah River Site (SRS), Aiken, SC (United States); White, T. [Savannah River Site (SRS), Aiken, SC (United States)

    2014-12-31

    Analysis of the recent WIPP samples are summarized in this report; WIPP Cam Filters 4, 6, 9 (3, 7, 11 were analyzed with FAS-118 in a separate campaign); WIPP Drum Lip R16 C4; WIPP Standard Waste Box R15 C5; WIPP MgO R16 C2; WIPP MgO R16 C4; WIPP MgO R16 C6; LANL swipes of parent drum; LANL parent drum debris; LANL parent drum; IAEA Swipe; Unused “undeployed” Swheat; Unused “undeployed” MgO; and Masselin cloth “smears”. Analysis showed that the MgO samples were very pure with low carbonate and water content. Other samples showed the expected dominant presence of Mg, Na and Pb. Parent drum debris sample was mildly acidic. Interpretation of results is not provided in this document, but rather to present and preserve the analytical work that was performed. The WIPP Technical Analysis Team is responsible for result interpretation which will be written separately.

  9. An Analysis of DoD Inspector General’s Statistical Sampling Plan for Navy Repairable Item Procurements

    Science.gov (United States)

    1994-06-01

    sampling, confidence intervals, and the inventory management definition of stratification. Chapter in presents all the data provided by the...important to understand that we are talking about the inventory management definition of stratification (also called "STRAT") which is an entirely separate

  10. The Navruz Project: Transboundary Monitoring for Radionuclides and Metals in Central Asia Rivers. Sampling and Analysis Plan and Operational Manual

    Energy Technology Data Exchange (ETDEWEB)

    Passell, Howard D.; Barber, David S.; Betsill, J. David; Littlfield, Adriane C.; Mohagheghi, Amir H.; Shanks, Sonoya T.; Yuldashev, Bekhzad; Salikhbaev, Umar; Radyuk, Raisa; Djuraev, Akram; Djuraev, Amwar; Vasilev, Ivan; Tolongutov, Bajgabyl; Valentina, Alekhina; Solodukhin, Vladimir; Pozniak, Victor

    2002-04-02

    The transboundary nature of water resources demands a transboundary approach to their monitoring and management. However, transboundary water projects raise a challenging set of problems related to communication issues, and standardization of sampling, analysis and data management methods. This manual addresses those challenges and provides the information and guidance needed to perform the Navruz Project, a cooperative, transboundary, river monitoring project involving rivers and institutions in Kazakhstan, Kyrgyzstan, Tajikistan, and Uzbekistan facilitated by Sandia National Laboratories in the U.S. The Navruz Project focuses on waterborne radionuclides and metals because of their importance to public health and nuclear materials proliferation concerns in the region. This manual provides guidelines for participants on sample and data collection, field equipment operations and procedures, sample handling, laboratory analysis, and data management. Also included are descriptions of rivers, sampling sites and parameters on which data are collected. Data obtained in this project are shared among all participating countries and the public through an internet web site, and are available for use in further studies and in regional transboundary water resource management efforts. Overall, the project addresses three main goals: to help increase capabilities in Central Asian nations for sustainable water resources management; to provide a scientific basis for supporting nuclear transparency and non-proliferation in the region; and to help reduce the threat of conflict in Central Asia over water resources, proliferation concerns, or other factors.

  11. Soil sampling and analysis plan for the Bear Creek Valley floodplain at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-11-01

    This Sampling and Analysis Plan (SAP) for the Bear Creek Valley (BCV) Floodplain presents the approach and rationale for characterizing potentially contaminated soils and sediments of the Bear Creek floodplain and the impact of any contaminants on the floodplain ecosystem. It is an addendum to a previously issued document, the Remedial Investigation Work Plan for Bear Creek (Y02-S600) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee (ES/ER-19&D2), which presents background information pertaining to this floodplain investigation. The strategy presented in the SAP is to divide the investigation into three component parts: a large-scale characterization of the floodplain; a fine-scale characterization of the floodplain beginning with a known contaminated location; and a stream sediment characterization. During the large-scale and the fine-scale characterizations, soil and biota samples (i.e., small mammals, earthworms, and vegetation) will be collected in order to characterize the nature and extent of floodplain soil contamination and the impact of this contamination on floodplain biota. The fine-scale characterization will begin with an investigation of a site corresponding to the location noted in the Remedial Investigation Work Plan (ES/ER-19&D2) as an area where uranium and PCBs are concentrated in discrete strata. During this fine-scale characterization, a 1 m deep soil profile excavation will be dug into the creek berm, and individual soil strata in the excavation will be screened for alpha radiation, PCBs, and VOCs. After the laboratory analysis results are received, biota samples will be collected in the vicinity of those locations.

  12. Sorting and cost analysis of reworking items in rejected lots based on non-destructive variable sampling plan

    Directory of Open Access Journals (Sweden)

    H. Y. Alkahby

    1999-12-01

    Full Text Available A mathematical model for a decision criterion for disposing an inspection lot is developed. An expression of the posterior cost is formulated in terms of the quality characteristics $X$ of the items manufactured, the sample size $n$, the lot size $N$, the upper and lower limits of $X$ ($U$, $L$ of the individual items, the sample mean $overline{x}$, the mean $mu$ and variance $sigma^2$ of $X$, also in terms of the economical cost parameters, Optimizing the posterior cost equation leads to the estimation of the decision points. A procedure to accept, reject, screen or scrap the entire lot based on the values of the decision points is developed. Mathematical expressions are derived for the expected cost of lot acceptance, screening and scrapping. In developing the model, the distribution of $X$ and $mu$ are normal. The tested items can be used for their intended purposes after testing. The defective items can be repaired or reworked. Rejected lots are either screened or scrapped. The decision to accept or reject a lot depends on the upper and lower limits of the sample mean, which constitutes the decision points.

  13. QUANTITATIVE FLUORESCENCE IN-SITU HYBRIDIZATION OF BIFIDOBACTERIUM SPP WITH GENUS-SPECIFIC 16S RIBOSOMAL-RNA-TARGETED PROBES AND ITS APPLICATION IN FECAL SAMPLES

    NARCIS (Netherlands)

    LANGENDIJK, PS; SCHUT, F; JANSEN, GJ; RAANGS, GC; KAMPHUIS, GR; WILKINSON, MHF; WELLING, GW

    1995-01-01

    Three 16S rRNA hybridization probes were developed and tested for genus-specific detection of Bifidobacterium species in the human fecal flora. Variable regions V2, V4, and VS of the 16S rRNA contained sequences unique to this genus and proved applicable as target sites for oligodeoxynucleotide prob

  14. Reliability evaluation of sampling plan fixed by Council Directive 91/68/EEC for the maintenance of officially brucellosis-free flock status.

    Science.gov (United States)

    De Massis, F; Petrini, A; Giovannini, A

    2005-08-01

    The European Union (EU) strategy with respect to sheep and goat brucellosis aims to eradicate the infection and achieve officially brucellosis-free (OBF) status in all EU holdings and territories. Council Directive 91/68/EEC of 28 January 1991 states that to maintain OBF status of ovine or caprine holdings located outside an OBF territory, only a representative number of animals need to be tested annually. However, depending on the number of animals in a holding, this testing method risks non-detection of the infection, thereby reducing the efficacy of the brucellosis control plan. The recommended sampling procedure has a low sensitivity for detecting infection in medium-sized flocks; furthermore, the risk of not detecting re-infection in OBF flocks, particularly in territories that have not yet gained OBF status, is also not acceptable. Moreover, in large-sized flocks, the Directive sampling procedure entails taking an excessive number of samples, which can be very expensive. The authors evaluated, by using statistical analyses and a simulation model based on field data, the possible consequences of the current EU strategy. It is suggested that the sampling criteria for the maintenance of OBF status in the EU should be modified and that a statistically based sampling method should be applied instead of the fixed percentage method that is currently in use.

  15. Sampling and analysis plan for the site characterization of the waste area Grouping 1 groundwater operable unit at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-11-01

    Waste Area Grouping (WAG) 1 at Oak Ridge National Laboratory (ORNL) includes all of the former ORNL radioisotope research, production, and maintenance facilities; former waste management areas; and some former administrative buildings. Site operations have contaminated groundwater, principally with radiological contamination. An extensive network of underground pipelines and utilities have contributed to the dispersal of contaminants to a known extent. In addition, karst geology, numerous spills, and pipeline leaks, together with the long and varied history of activities at specific facilities at ORNL, complicate contaminant migration-pathway analysis and source identification. To evaluate the extent of contamination, site characterization activity will include semiannual and annual groundwater sampling, as well as monthly water level measurements (both manual and continuous) at WAG 1. This sampling and analysis plan provides the methods and procedures to conduct site characterization for the Phase 1 Remedial Investigation of the WAG 1 Groundwater Operable Unit.

  16. Final work plan : indoor air and ambient air sampling near the former CCC/USDA grain storage facility in Everest, Kansas.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M. (Environmental Science Division)

    2010-05-24

    The Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) operated a grain storage facility at the western edge of Everest, Kansas, from the early 1950s to the early 1970s. Sampling by the Kansas Department of Health and Environment (KDHE) in 1997 resulted in the detection of carbon tetrachloride in one domestic well (the Nigh well) northwest of the former facility. On behalf of the CCC/USDA, Argonne National Laboratory subsequently conducted a series of investigations to characterize the contamination (Argonne 2003, 2006a,b,c). Automatic, continuous monitoring of groundwater levels began in 2002 and is ongoing at six locations. The results have consistently indicated groundwater flow toward the north-northwest from the former CCC/USDA property to the Nigh property, then west-southwest from the Nigh property to the intermittent creek. Sitewide periodic groundwater and surface water sampling with analysis for volatile organic compounds (VOCs) began in 2008. Argonne's combined data indicate no significant downgradient extension of contamination since 2000. At present, the sampling is annual, as approved by the KDHE (2009) in response to a plan developed for the CCC/USDA (Argonne 2009). This document presents a plan for collecting indoor air samples in homes located along and adjacent to the defined extent of the carbon tetrachloride contamination. The plan was requested by the KDHE. Ambient air samples to represent the conditions along this pathway will also be taken. The purpose of the proposed work is to satisfy KDHE requirements and to collect additional data for assessing the risk to human health due to the potential upward migration of carbon tetrachloride and its primary degradation product (chloroform) into homes located in close proximity to the former grain storage facility, as well as along and within 100 ft laterally from the currently defined plume emanating from the former Everest facility. Investigation of the indoor air

  17. On the efficiency of the hybrid and the exact second-order sampling formulations of the EnKF: a reality-inspired 3-D test case for estimating biodegradation rates of chlorinated hydrocarbons at the port of Rotterdam

    Science.gov (United States)

    Gharamti, Mohamad E.; Valstar, Johan; Janssen, Gijs; Marsman, Annemieke; Hoteit, Ibrahim

    2016-11-01

    This study considers the assimilation problem of subsurface contaminants at the port of Rotterdam in the Netherlands. It involves the estimation of solute concentrations and biodegradation rates of four different chlorinated solvents. We focus on assessing the efficiency of an adaptive hybrid ensemble Kalman filter and optimal interpolation (EnKF-OI) and the exact second-order sampling formulation (EnKFESOS) for mitigating the undersampling of the estimation and observation errors covariances, respectively. A multi-dimensional and multi-species reactive transport model is coupled to simulate the migration of contaminants within a Pleistocene aquifer layer located around 25 m below mean sea level. The biodegradation chain of chlorinated hydrocarbons starting from tetrachloroethene and ending with vinyl chloride is modeled under anaerobic environmental conditions for 5 decades. Yearly pseudo-concentration data are used to condition the forecast concentration and degradation rates in the presence of model and observational errors. Assimilation results demonstrate the robustness of the hybrid EnKF-OI, for accurately calibrating the uncertain biodegradation rates. When implemented serially, the adaptive hybrid EnKF-OI scheme efficiently adjusts the weights of the involved covariances for each individual measurement. The EnKFESOS is shown to maintain the parameter ensemble spread much better leading to more robust estimates of the states and parameters. On average, a well tuned hybrid EnKF-OI and the EnKFESOS respectively suggest around 48 and 21 % improved concentration estimates, as well as around 70 and 23 % improved anaerobic degradation rates, over the standard EnKF. Incorporating large uncertainties in the flow model degrades the accuracy of the estimates of all schemes. Given that the performance of the hybrid EnKF-OI depends on the quality of the background statistics, satisfactory results were obtained only when the uncertainty imposed on the background

  18. On the efficiency of the hybrid and the exact second-order sampling formulations of the EnKF: a reality-inspired 3-D test case for estimating biodegradation rates of chlorinated hydrocarbons at the port of Rotterdam

    KAUST Repository

    El Gharamti, Mohamad

    2016-11-15

    This study considers the assimilation problem of subsurface contaminants at the port of Rotterdam in the Netherlands. It involves the estimation of solute concentrations and biodegradation rates of four different chlorinated solvents. We focus on assessing the efficiency of an adaptive hybrid ensemble Kalman filter and optimal interpolation (EnKF-OI) and the exact second-order sampling formulation (EnKFESOS) for mitigating the undersampling of the estimation and observation errors covariances, respectively. A multi-dimensional and multi-species reactive transport model is coupled to simulate the migration of contaminants within a Pleistocene aquifer layer located around 25 m below mean sea level. The biodegradation chain of chlorinated hydrocarbons starting from tetrachloroethene and ending with vinyl chloride is modeled under anaerobic environmental conditions for 5 decades. Yearly pseudo-concentration data are used to condition the forecast concentration and degradation rates in the presence of model and observational errors. Assimilation results demonstrate the robustness of the hybrid EnKF-OI, for accurately calibrating the uncertain biodegradation rates. When implemented serially, the adaptive hybrid EnKF-OI scheme efficiently adjusts the weights of the involved covariances for each individual measurement. The EnKFESOS is shown to maintain the parameter ensemble spread much better leading to more robust estimates of the states and parameters. On average, a well tuned hybrid EnKF-OI and the EnKFESOS respectively suggest around 48 and 21 % improved concentration estimates, as well as around 70 and 23 % improved anaerobic degradation rates, over the standard EnKF. Incorporating large uncertainties in the flow model degrades the accuracy of the estimates of all schemes. Given that the performance of the hybrid EnKF-OI depends on the quality of the background statistics, satisfactory results were obtained only when the uncertainty imposed on the background

  19. Hybrid Baryons

    CERN Document Server

    Page, P R

    2003-01-01

    We review the status of hybrid baryons. The only known way to study hybrids rigorously is via excited adiabatic potentials. Hybrids can be modelled by both the bag and flux-tube models. The low-lying hybrid baryon is N 1/2^+ with a mass of 1.5-1.8 GeV. Hybrid baryons can be produced in the glue-rich processes of diffractive gamma N and pi N production, Psi decays and p pbar annihilation.

  20. Sampling Design Plan/Safety Plan

    Science.gov (United States)

    1986-01-01

    S TIOTAC.S_ _ _ _ S _ _ _ _ S__ _ _ _ _ _ _ _ _ S_ _ _ _ No. Trips GRANO TOTAL S I2. ___s___ ___s___ SLISCNTRACT0N(V)CQN$ULTAMTfSM EMA 6-1 N...r 9’ ___ _ 7-f__ A c0 V/9Y TOTAILS1 TRAV E.I AMC) SU 83STNCrA 3.I car~ 2w~ 3 -7 71 Taft ______ GRANO MTALS 3___ -T ____ ___ g~altzA W1,43...r1og _____ /00 _ _ _ M, A.S /10~ 2 /_ __ £ý 0_ _ _ S_ _ _ S _ _ _ S_ 3&. rcim GRANO TOTAI.S.i~.~ az𔃽 S__ _ _ _ _ _ _ _ ~ ASi~C7 !XPSNSISUm tei.,tic

  1. Moving GPU-OpenCL-based Monte Carlo dose calculation toward clinical use: Automatic beam commissioning and source sampling for treatment plan dose calculation.

    Science.gov (United States)

    Tian, Zhen; Li, Yongbao; Hassan-Rezaeian, Nima; Jiang, Steve B; Jia, Xun

    2017-03-01

    We have previously developed a GPU-based Monte Carlo (MC) dose engine on the OpenCL platform, named goMC, with a built-in analytical linear accelerator (linac) beam model. In this paper, we report our recent improvement on goMC to move it toward clinical use. First, we have adapted a previously developed automatic beam commissioning approach to our beam model. The commissioning was conducted through an optimization process, minimizing the discrepancies between calculated dose and measurement. We successfully commissioned six beam models built for Varian TrueBeam linac photon beams, including four beams of different energies (6 MV, 10 MV, 15 MV, and 18 MV) and two flattening-filter-free (FFF) beams of 6 MV and 10 MV. Second, to facilitate the use of goMC for treatment plan dose calculations, we have developed an efficient source particle sampling strategy. It uses the pre-generated fluence maps (FMs) to bias the sampling of the control point for source particles already sampled from our beam model. It could effectively reduce the number of source particles required to reach a statistical uncertainty level in the calculated dose, as compared to the conventional FM weighting method. For a head-and-neck patient treated with volumetric modulated arc therapy (VMAT), a reduction factor of ~2.8 was achieved, accelerating dose calculation from 150.9 s to 51.5 s. The overall accuracy of goMC was investigated on a VMAT prostate patient case treated with 10 MV FFF beam. 3D gamma index test was conducted to evaluate the discrepancy between our calculated dose and the dose calculated in Varian Eclipse treatment planning system. The passing rate was 99.82% for 2%/2 mm criterion and 95.71% for 1%/1 mm criterion. Our studies have demonstrated the effectiveness and feasibility of our auto-commissioning approach and new source sampling strategy for fast and accurate MC dose calculations for treatment plans. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by

  2. Evaluation of kDNA PCR hybridization and ITS1 nPCR methods in different clinical samples for visceral leishmaniasis diagnosis in dogs with and without clinical signs

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Aline Leandra C.; Carregal, Virginia M.; Leite, Rodrigo S.; Ferreira, Sidney A.; Andrade, Antero Silva R., E-mail: alineleandra@hotmail.com, E-mail: streptos@hotmail.com, E-mail: rleite2005@gmail.com, E-mail: vidasnino@yahoo.com.br, E-mail: antero@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Lab. de Radiobiologia; Melo, Maria N., E-mail: melo@icb.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Parasitologia

    2013-07-01

    Visceral leishmaniasis (VL) in Brazil is caused by Leishmania infantum and dogs are considered the main domestic reservoirs of this parasite. The VL control program in Brazil emphasizes the use of serological surveys, followed by elimination of seropositive dogs. However, serologic tests have limitations in terms of sensitivity and specificity. Molecular methods such as PCR (Polymerase Chain Reaction) associated with hybridization using {sup 32}P radiolabeled DNA probes (kDNA PCR hybridization) are useful tools in this scenario, since they are more specific and sensitive than conventional methods. A variety of samples can be employed with PCR; however non-invasive procedures are the most adequate. One of main obstacles for implementation of PCR in the canine visceral leishmaniasis (CVL) diagnosis is the lack of standardization. Few studies up to the moment compared the effectiveness of the different PCR methods and clinical samples available. The objective of this study was to compare the kDNA PCR hybridization and the Internal Transcribed Spacer 1 nested PCR (ITS1 nPCR) methods and four types of clinical samples for the diagnosis of CVL in dogs with and without clinical signs of the disease. The methods were compared using samples of conjunctival swab (SC), bone marrow (BM), skin (S) and peripheral blood (PB). A group of 60 mongrel dogs, all positive in serological and parasitological tests, were equally divided in two groups: S (with clinical signs) and A (without clinical signs). The frequencies of positive results for the kDNA PCR hybridization in the S group were: CS 97% (29/30), BM 83 % (25/30), S 63% (19/30) and PB 4 7% (14/30). By the same method the following results were obtained in the A group: CS 70% (21/30), BM 63% (19/30), S 57% (17/30) and PB 17% (5/30). The ITS1 nPCR allowed the following positivities for the S group: CS 83% (25/30), BM 97% (29/30), S 83% (25/30) and PB 70% (21/30). For the A group the following results were obtained: CS and BM 83

  3. Aerobic physical activity and resistance training: an application of the theory of planned behavior among adults with type 2 diabetes in a random, national sample of Canadians.

    Science.gov (United States)

    Plotnikoff, Ronald C; Courneya, Kerry S; Trinh, Linda; Karunamuni, Nandini; Sigal, Ronald J

    2008-12-02

    Aerobic physical activity (PA) and resistance training are paramount in the treatment and management of type 2 diabetes (T2D), but few studies have examined the determinants of both types of exercise in the same sample. The primary purpose was to investigate the utility of the Theory of Planned Behavior (TPB) in explaining aerobic PA and resistance training in a population sample of T2D adults. A total of 244 individuals were recruited through a random national sample which was created by generating a random list of household phone numbers. The list was proportionate to the actual number of household telephone numbers for each Canadian province (with the exception of Quebec). These individuals completed self-report TPB constructs of attitude, subjective norm, perceived behavioral control and intention, and a 3-month follow-up that assessed aerobic PA and resistance training. TPB explained 10% and 8% of the variance respectively for aerobic PA and resistance training; and accounted for 39% and 45% of the variance respectively for aerobic PA and resistance training intentions. These results may guide the development of appropriate PA interventions for aerobic PA and resistance training based on the TPB.

  4. Aerobic physical activity and resistance training: an application of the theory of planned behavior among adults with type 2 diabetes in a random, national sample of Canadians

    Directory of Open Access Journals (Sweden)

    Karunamuni Nandini

    2008-12-01

    Full Text Available Abstract Background Aerobic physical activity (PA and resistance training are paramount in the treatment and management of type 2 diabetes (T2D, but few studies have examined the determinants of both types of exercise in the same sample. Objective The primary purpose was to investigate the utility of the Theory of Planned Behavior (TPB in explaining aerobic PA and resistance training in a population sample of T2D adults. Methods A total of 244 individuals were recruited through a random national sample which was created by generating a random list of household phone numbers. The list was proportionate to the actual number of household telephone numbers for each Canadian province (with the exception of Quebec. These individuals completed self-report TPB constructs of attitude, subjective norm, perceived behavioral control and intention, and a 3-month follow-up that assessed aerobic PA and resistance training. Results TPB explained 10% and 8% of the variance respectively for aerobic PA and resistance training; and accounted for 39% and 45% of the variance respectively for aerobic PA and resistance training intentions. Conclusion These results may guide the development of appropriate PA interventions for aerobic PA and resistance training based on the TPB.

  5. Hybrid2 - The hybrid power system simulation model

    Energy Technology Data Exchange (ETDEWEB)

    Baring-Gould, E.I.; Green, H.J.; Dijk, V.A.P. van [National Renewable Energy Lab., Golden, CO (United States); Manwell, J.F. [Univ. of Massachusetts, Amherst, MA (United States)

    1996-12-31

    There is a large-scale need and desire for energy in remote communities, especially in the developing world; however the lack of a user friendly, flexible performance prediction model for hybrid power systems incorporating renewables hindered the analysis of hybrids as options to conventional solutions. A user friendly model was needed with the versatility to simulate the many system locations, widely varying hardware configurations, and differing control options for potential hybrid power systems. To meet these ends, researchers from the National Renewable Energy Laboratory (NREL) and the University of Massachusetts (UMass) developed the Hybrid2 software. This paper provides an overview of the capabilities, features, and functionality of the Hybrid2 code, discusses its validation and future plans. Model availability and technical support provided to Hybrid2 users are also discussed. 12 refs., 3 figs., 4 tabs.

  6. Groundwater level monitoring sampling and analysis plan for environmental monitoring in Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    This Sampling and Analysis Plan addresses groundwater level monitoring activities that will be conducted in support of the Environmental Monitoring Plan for Waste Area Grouping (WAG) 6. WAG 6 is a shallow-burial land disposal facility for low-level radioactive waste at the Oak Ridge National Laboratory, a research facility owned by the US Department of Energy and managed by Martin Marietta Energy Systems, Inc. Groundwater level monitoring will be conducted at 129 sites within the WAG. All of the sites will be manually monitored on a semiannual basis. Forty-five of the 128 wells, plus one site in White Oak Lake, will also be equipped with automatic water level monitoring equipment. The 46 sites are divided into three groups. One group will be equipped for continuous monitoring of water level, conductivity, and temperature. The other two groups will be equipped for continuous monitoring of water level only. The equipment will be rotated between the two groups. The data collected from the water level monitoring will be used to support determination of the contaminant flux at WAG 6.

  7. 基于遗传算法的四自由度混联机器人轨迹规划%Trajectory Planning of Four DOF Hybrid Robot Based on Genetic Algorithm

    Institute of Scientific and Technical Information of China (English)

    陈小立; 严宏志; 温广旭

    2014-01-01

    研究机器人轨迹优化控制问题,为了兼顾机器人高速运动的平稳性与工作效率,以四自由度混联机器人为研究对象,提出了一种基于遗传算法的轨迹规划方案。运用坐标变换法建立混联机器人的运动学模型;在考虑机器人位置、速度、加速度约束的基础上,采用"3-5-3"法在关节空间对机器人进行轨迹规划。通过遗传算法对各路径点间的时间间隔进行最优规划,获得各关节的位置、速度、加速度轨迹图像。仿真结果表明,所设计的方案能保证机器人运行时间最优以及轨迹连续平滑。%In order to improve hybrid robot's productivity and get a smooth high-speed movement, a method for trajectory planning based on genetic algorithm was presented. The kinematic model of hybrid robot was established by coordinate transformation method;the robot's trajectory in joint space was planned by"3-5-3" method while consid-ering constraints of position,velocity and acceleration. In order to obtain the trajectory picture of each point's posi-tion, velocity and acceleration, the time intervals between each path point were planned with the genetic algorithm. The simulation results show that the method can make the working time optimal and the robot's trajectory smooth.

  8. Sampling and Analysis Plan for Assessment of LANL-Derived Residual Radionuclides in Soils within Tract A-16-e for Land Conveyance

    Energy Technology Data Exchange (ETDEWEB)

    Gillis, Jessica [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-25

    Public Law 105-119 directs the U.S. Department of Energy (DOE) to convey or transfer parcels of land to the Incorporated County of Los Alamos or their designees and to the Department of Interior, Bureau of Indian Affairs, in trust for the Pueblo de San Ildefonso. Los Alamos National Security is tasked to support DOE in conveyance and/or transfer of identified land parcels no later than September 2022. Under DOE Order 458.1, Radiation Protection of the Public and the Environment (O458.1, 2013), and Los Alamos National Laboratory (LANL) implementing Policy 412 (P412, 2014a), real property with the potential to contain residual radioactive material must meet the criteria for clearance and release to the public. This Sampling and Analysis Plan (SAP) investigates Tract A-16-e and proposes 50 project-specific soil samples for use in radiological clearance decisions consistent with LANL Procedure ENV-ES-TP-238 (2015a) and guidance in the Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM, 2000).

  9. Hybrid vehicles

    Energy Technology Data Exchange (ETDEWEB)

    West, J.G.W. [Electrical Machines (United Kingdom)

    1997-07-01

    The reasons for adopting hybrid vehicles result mainly from the lack of adequate range from electric vehicles at an acceptable cost. Hybrids can offer significant improvements in emissions and fuel economy. Series and parallel hybrids are compared. A combination of series and parallel operation would be the ideal. This can be obtained using a planetary gearbox as a power split device allowing a small generator to transfer power to the propulsion motor giving the effect of a CVT. It allows the engine to run at semi-constant speed giving better fuel economy and reduced emissions. Hybrid car developments are described that show the wide range of possible hybrid systems. (author)

  10. Plano de amostragem para Dichopelmus notus (Eriophyidae na cultura da erva-mate Sampling plan for Dichopelmus notus (Eriophyidae on mate-tea orchard

    Directory of Open Access Journals (Sweden)

    Guilherme Bertoldo

    2008-06-01

    Full Text Available O objetivo deste trabalho foi avaliar a amostragem presença-ausência para Dichopelmus notus Keifer (Eriophyidae na cultura da erva-mate. O trabalho foi realizado em plantação comercial, em Cascavel, PR, entre abril de 1999 e julho de 2000. Procederam-se a coletas quinzenais de 240 folhas em diferentes partes de 10 plantas. A contagem dos ácaros nas folhas foi realizada, em laboratório, com auxílio de microscópio estereoscópico. Foi determinado o padrão de agregação com o modelo da potência de Taylor, e também a proporção de folhas infestadas e o número de amostras requeridas foram estimados por análise de regressão. D. notus apresentou distribuição agregada. A proporção de folhas infestadas estimadas pelo modelo matemático mostrou ser um parâmetro confiável para se estimar a densidade populacional do ácaro, sendo que o número de amostras requeridas foi pequeno, o que viabiliza a aplicação prática do método.The objective of this research was to evaluate presence-absence sampling plan for Dichopelmus notus Keifer (Eriophyidae on mate-tea orchard. This study was conducted in Cascavel, State of Paraná, Brazil, from April 1999 to July 2000, in a mate-tea tree commercial plantation. Biweekly sampling of 240 leaves in different parts of 10 plants was conducted, and the number of mites was registered. The aggregation pattern was determined using the Taylor’s power law model. The proportion of the infested leaves and the number of required samples were estimated by regression analysis. D. notus presented aggregated distribution. The estimated proportion of infested leaves showed to be reliable in order to estimate the population density of mites. The number of sample unities required to estimate infestation density was low, which makes practical application of this sampling method to be feasible.

  11. Planning Method for Hybrid Energy Microgrid Based on Dynamic Operation Strategy%基于动态运行策略的混合能源微网规划方法

    Institute of Scientific and Technical Information of China (English)

    杨艳红; 裴玮; 齐智平

    2012-01-01

    A system planning model is proposed considering the operation strategy constraint of hybrid energy microgrid.A hybrid energy system model is established including solar power,wind power,micro-turbine and energy storages.Taking the minimum annual net cash flows as the target,an example analysis is used to design a smart park hybrid energy system,and a variable step space search process is used to achieve the best distributed power unit capacity.According to the optimal result,the system energy balance relationship in different seasons and times is analyzed,and the influence of time of use power price on the microgrid operation is discussed.%在考虑混合能源微网动态运行策略约束的同时,提出了建立系统规划模型的方法,并建立了包含光伏发电、风力发电、微型燃气轮机热电联供和储能的混合能源微网规划模型。以年现金流最小为优化目标,结合算例分析对某办公园区混合能源微网系统进行了规划设计,采用变步长空间搜索方法计算得出最佳分布式发电单元容量,分析了算例系统在不同季节和时刻的能量平衡关系,讨论了分时电价对混合能源微网系统运行的影响。

  12. 基于遗传模拟退火算法的车间布局规划研究%Research on Workshop’s Layout Planning Based on the Genetic Simulated Annealing Hybrid Algorithm

    Institute of Scientific and Technical Information of China (English)

    宛剑业; 张飞超; 高丽媛; 刘卫博

    2016-01-01

    针对YY企业电子油门生产车间的布局规划,分别采用了传统的SLP方法和遗传模拟退火算法,并利用 Proplanner 软件对其两种方法获得的方案1、2进行了仿真研究。仿真结果表明在零部件的搬运距离、搬运时间、搬运成本三方面,方案2明显优于方案1。从而说明在车间布局规划方面,遗传模拟退火算法比SLP更具可行性与合理性。%To study the layout planning for electronic accelerator production workshop of YY company, this paper uses SLP method and the genetic simulated annealing hybrid algorithm, and the Proplanner software to conduct the simulation research of the program 1, 2 obtained on the two methods. The simulation results show that the program 2 is obviously better than program 1 in the parts of the distance of transportation, handling time, handling cost, which means that the genetic simulated annealing hybrid algorithm is more feasible and rational than the SLP in the layout of a workshop.

  13. Covalent Bonding of Metal-Organic Framework-5/Graphene Oxide Hybrid Composite to Stainless Steel Fiber for Solid-Phase Microextraction of Triazole Fungicides from Fruit and Vegetable Samples.

    Science.gov (United States)

    Zhang, Shuaihua; Yang, Qian; Wang, Wenchang; Wang, Chun; Wang, Zhi

    2016-04-06

    A hybrid material of the zinc-based metal-organic framework-5 and graphene oxide (metal-organic framework-5/graphene oxide) was prepared as a novel fiber coating material for solid-phase microextraction (SPME). The SPME fibers were fabricated by covalent bonding via chemical cross-linking between the coating material metal-organic framework-5/graphene oxide and stainless steel wire. The prepared fiber was used for the extraction of five triazole fungicides from fruit and vegetable samples. Gas chromatography coupled with microelectron capture detector (GC-μECD) was used for quantification. The developed method gave a low limit of detection (0.05-1.58 ng g(-1)) and good linearity (0.17-100 ng g(-1)) for the determination of the triazole fungicides in fruit and vegetable samples. The relative standard deviations (RSDs) for five replicate extractions of the triazole fungicides ranged from 3.7 to 8.9%. The method recoveries for spiked fungicides (5, 20, and 50 ng g(-1)) in grape, apple, cucumber, celery cabbage, pear, cabbage, and tomato samples were in the range of 85.6-105.8% with the RSDs ranging from 3.6 to 11.4%, respectively, depending on both the analytes and samples. The metal-organic framework-5/graphene oxide coated fiber was stable enough for 120 extraction cycles without a significant loss of extraction efficiency. The method was suitable for the determination of triazole fungicides in fruit and vegetable samples.

  14. Optimization of Fluorescence in Situ Hybridization for the Detection of Bacteria in Sausage Samples%火腿肠细菌总数FISH检测技术的优化

    Institute of Scientific and Technical Information of China (English)

    何庆; 罗剑飞; 林炜铁; 井洪珍

    2013-01-01

    In order to develop a method that rapidly detect and enumerate the bacteria in sausage samples. The Fluorescence in situ hybridization (FISH) technique with EUB338 probe was established and optimized. Three different cell-fixing methods were contrasted and results showed that the optimal conditions for sample preparation were 4% paraformaldehyde, fixed time IS min, at 4℃and heat fixed time 2 h at 46℃. The optimal condition for hybridization was 3 h hybridized at 46°C with 225 mmol/L NaCl concentration in washing buffer. Compared to the Plate count method, the optimized FISH method was more sensitive and quicker while used to enumerate the bacteria in sausage samples. The FISH method can be used as an effective and convenient tool for the detection and enumeration of bacteria in food samples.%为了建立快速的火腿肠中细菌检测和计数方法,本文采用细菌通用探针EUB338作为标记,优化了荧光原位杂交(FISH)技术检测火腿肠中细菌的方法.比较了三种细胞固定方法,结果表明最佳的样品预处理方法为:4℃4%多聚甲醛固定15min,46℃热固定2 h;最佳的杂交条件:杂交温度为46℃,杂交时间为3h,杂交洗脱液浓度为225 mmol/L;优化的FISH方法应用于火腿肠样品的总菌数的检测,并且将FISH方法对火腿肠样品的细菌计数与传统平板计数方法进行比较,结果显示FISH方法相较于平板计数方法检出数高,而且所需时间大大缩短,操作起来更加方便、简捷.本实验充分体现了FISH快速定量的优势,FISH可以作为食品微生物快速检测的一种有效工具.

  15. Network Planning Model and its Hybrid Genetic Algorithm for the Price-Sensitive Supply Chain%价格敏感型供应链网络规划模型及其混合遗传算法

    Institute of Scientific and Technical Information of China (English)

    王建华; 李南; 罗建强; 郭慧

    2011-01-01

    In a price-sensitive supply chain, each business partner as independent profit unit defines the relationship between batch order and ordering price based on members' profit preferences and resource conditions. The ordering quality of products is strongly related to a member' s price decision-making processes for purchasing, supplying, production, logistics and selling activities. The operating cost and profit of a supply chain is different from that of total product quantity and distribution. Planning can reduce operating cost and improve profitability and market competitiveness for a price-sensitive supply chain. An effective planning can further lower resource consumption and make contributions to sustainable development of society and economy.This research studies a four-stage price-sensitive supply chain consisting of multiple suppliers, one manufacturer, multiple distribution centers and multiple retailers. A manufacturer needs to make decisions on supply chain network planning activities, such as supplier selection for parts and logistics support, sourcing from different suppliers, and distribution and selling of final products via different retailers. The network planning problem is complicated and requires supply chain managers apply a good decision-making algorithm to obtain a satisfactory solution on a timely basis.We first build an integer non-linear planning (INLP) model to represent network planning problems. We then use the heuristic repair method embedded with the hybrid genetic algorithm ( HCA ) to resolve the model. Finally, we use simulations to verify the model validity, as well as the stability and efficiency of the algorithm. It is essential to build a general structure model and mathematical model for optimizing supply chain planning due to the multi-forms of actual supply chains.In the first part, we describe the planning problem in detail, and design a general structure model for supply chains to represent the relationships among the members

  16. Correlation and comparison of immunohistochemistry for HER2/neu, using the antibody SP3 and chromogenic in situ hybridization in breast carcinomas samples

    Directory of Open Access Journals (Sweden)

    Franciele F. Wolf

    2015-12-01

    Full Text Available ABSTRACT Introduction: Advances in the field of molecular biology have provided the differentiation of molecular subtypes of breast tumors, providing better prognosis and important tools for the treatment of patients with breast cancer. Among these subtypes, the changes in the human epidermal growth factor receptor 2 gene (HER2/neu, increase its copy number and generating HER2 protein amplification. Studies show that patients with breast cancer HER2/neu amplified tend to relapse earlier and have shorter survival time, the monoclonal antibody Trastuzumab is the therapy indicated. The eligibility of patients for therapy is initially made by the immunohistochemistry (IHC technique, which evaluates the expression level of the HER2 protein. After this evaluation, the cases with equivocal diagnosis (score 2+, are referred to a more accurate technique, the chromogenic in situ hybridization (CISH. Objective: To analyze the sensitivity and specificity of the antibody SP3, and determine their level of agreement with the CISH technique. Material and methods: Retrospective study in the database of the anatomy-pathology laboratory, in CISH tests reports for HER2/neu. Conclusion: The results revealed that clone SP3 showed 100% specificity and 92% sensitivity. IHC reveals variability in its results; however, it is known that the technique is an important tool in the daily routine of laboratories, contributing to the initial screening of patients with breast cancer, which later showed satisfactory results when compared with the CISH technique.

  17. Distribuição espacial e plano de amostragem de Calacarus heveae (Acari em seringueira Spatial distribution and sampling plan for Calacarus heveae (Acari on rubber trees

    Directory of Open Access Journals (Sweden)

    Noeli Juarez Ferla

    2007-12-01

    representative sampling unit and to develop a sampling plan to determine the populational fluctuation. This study was conducted with clones PB 260 and IAN 873, in Itiquira and Pontes e Lacerda, respectively, both in the state of Mato Grosso. In Itiquira, significant differences were observed in four occasions in relation to the average number of mites per leaf in the different plant strata. In the samplings carried out in Pontes e Lacerda, no significant differences were observed between strata in relation to that parameter. Only in Itiquira, in one occasion, a significant difference between strata was verified in relation to the proportion of infested leaves. No significant differences were verified in relation to the average number of mites per leaf and proportion of leaves infested by C. heveae at different depths in the canopy. Calacarus heveae exhibits aggregated distribution in the field. To estimate the density of C. heveae, numeric and sampling plans were developed.

  18. Atlas-guided generation of pseudo-CT images for MRI-only and hybrid PET-MRI-guided radiotherapy treatment planning

    NARCIS (Netherlands)

    Arabi, Hossein; Koutsouvelis, Nikolaos; Rouzaud, Michel; Miralbell, Raymond; Zaidi, Habib

    2016-01-01

    Magnetic resonance imaging (MRI)-guided attenuation correction (AC) of positron emission tomography (PET) data and/or radiation therapy (RT) treatment planning is challenged by the lack of a direct link between MRI voxel intensities and electron density. Therefore, even if this is not a trivial

  19. Atlas-guided generation of pseudo-CT images for MRI-only and hybrid PET-MRI-guided radiotherapy treatment planning

    NARCIS (Netherlands)

    Arabi, Hossein; Koutsouvelis, Nikolaos; Rouzaud, Michel; Miralbell, Raymond; Zaidi, Habib

    2016-01-01

    Magnetic resonance imaging (MRI)-guided attenuation correction (AC) of positron emission tomography (PET) data and/or radiation therapy (RT) treatment planning is challenged by the lack of a direct link between MRI voxel intensities and electron density. Therefore, even if this is not a trivial task

  20. Can the Theory of Planned Behavior predict dietary intention and future dieting in an ethnically diverse sample of overweight and obese veterans attending medical clinics?

    Science.gov (United States)

    Lash, Denise N; Smith, Jane Ellen; Rinehart, Jenny K

    2016-04-01

    Obesity has become a world-wide epidemic; in the United States (U.S.) approximately two-thirds of adults are classified as overweight or obese. Military veterans' numbers are even higher, with 77% of retired or discharged U.S. veterans falling in these weight categories. One of the most common methods of changing one's weight is through dieting, yet little is known regarding the factors that facilitate successful dieting behavior. The current investigation tested the Theory of Planned Behavior's (TPB) ability to predict dietary intention and future dieting in a sample of 84 overweight and obese patients attending medical clinics at a Veterans Affairs Hospital in the southwestern part of the U.S. Participants primarily were male (92%) and ethnic/racial minorities (58%). Perceived need and anticipated regret were added to the standard TPB model. While the TPB predicted dietary intention, it did not significantly account for improved dietary behaviors. Anticipated regret significantly enhanced the basic TPB's ability to predict intention to diet, while perceived need did not. These findings highlight the difficulty in predicting sustained change in a complex behavior such as dieting to lose weight. The need for more work with older, overweight/obese medical patients attending veterans' facilities is stressed, as is the need for such work with male patients and ethnic minorities in particular. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Can the Theory of Planned Behavior Predict Dietary Intention and Future Dieting in an Ethnically Diverse Sample of Overweight and Obese Veterans Attending Medical Clinics?

    Science.gov (United States)

    Lash, Denise N.; Smith, Jane Ellen; Rinehart, Jenny K.

    2016-01-01

    Obesity has become a world-wide epidemic; in the United States (U.S.) approximately two-thirds of adults are classified as overweight or obese. Military veterans’ numbers are even higher, with 77% of retired or discharged U.S. veterans falling in these weight categories. One of the most common methods of changing one’s weight is through dieting, yet little is known regarding the factors that facilitate successful dieting behavior. The current investigation tested the Theory of Planned Behavior’s (TPB) ability to predict dietary intention and future dieting in a sample of 84 overweight and obese patients attending medical clinics at a Veterans Affairs Hospital in the southwestern part of the U.S. Participants primarily were male (92%) and ethnic/racial minorities (58%). Perceived need and anticipated regret were added to the standard TPB model. While the TPB predicted dietary intention, it did not significantly account for improved dietary behaviors. Anticipated regret significantly enhanced the basic TPB’s ability to predict intention to diet, while perceived need did not. These findings highlight the difficulty in predicting sustained change in a complex behavior such as dieting to lose weight. The need for more work with older, overweight/obese medical patients attending veterans’ facilities is stressed, as is the need for such work with male patients and ethnic minorities in particular. PMID:26792774

  2. 基于多级混合空间索引的境界数据组织模型%Based on the state of multistage hybrid spatial index sample figure data organization model

    Institute of Scientific and Technical Information of China (English)

    刘静祯; 宋文浩; 程志刚

    2015-01-01

    Boundary sample data is the important basis of state audit, in the state of automated audit system, efficient management and retrieval state image data is the key to the system. In this paper, through analyzing the characteristics of the boundary sample plot data, comprehensive than the mature data index method, is proposed based on the state of multistage hybrid spatial index sample figure data organization model, and illustrates the indexes to establish the basic principle and implement mechanism, for the boundary sample in figure in a computer store management provides effective support.%境界样图数据是境界审核的重要依据,在自动化的境界审核系统中,高效管理和检索境界样图数据是系统的关键。本文通过分析境界样图数据的特点,综合比对目前成熟的数据索引方式,提出了基于多级混合空间索引的境界样图数据组织模型,阐明了索引建立的基本原理和实现机制,为境界样图在计算机中的储存管理提供了有效支撑。

  3. Bechtel Jacobs Company LLC Sampling and Analysis Plan for the Water Resources Restoration Program for Fiscal Year 2009, Oak Ridge Reservation, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Ketelle R.H.

    2008-09-25

    Analysis Plan (SAP). A brief summary is given of the organization of the SAP appendices, which provide the monitoring specifics and details of sampling and analytical requirements for each of the water quality programs on the ORR. Section 2 of this SAP provides a brief overview and monitoring strategy for the ETTP. Section 3 discusses monitoring strategy for Bethel Valley, and Melton Valley background information and monitoring strategy is provided in Section 4. BCV and UEFPC monitoring strategies are presented in Sect. 5 and 6, respectively. Section 7 provides background information and monitoring strategy for all off-site locations.

  4. Conditional Hybrid Nonclassicality

    Science.gov (United States)

    Agudelo, E.; Sperling, J.; Costanzo, L. S.; Bellini, M.; Zavatta, A.; Vogel, W.

    2017-09-01

    We derive and implement a general method to characterize the nonclassicality in compound discrete- and continuous-variable systems. For this purpose, we introduce the operational notion of conditional hybrid nonclassicality which relates to the ability to produce a nonclassical continuous-variable state by projecting onto a general superposition of discrete-variable subsystem. We discuss the importance of this form of quantumness in connection with interfaces for quantum communication. To verify the conditional hybrid nonclassicality, a matrix version of a nonclassicality quasiprobability is derived and its sampling approach is formulated. We experimentally generate an entangled, hybrid Schrödinger cat state, using a coherent photon-addition process acting on two temporal modes, and we directly sample its nonclassicality quasiprobability matrix. The introduced conditional quantum effects are certified with high statistical significance.

  5. Application of poly 1,8-diaminonaphthalene/multiwalled carbon nanotubes-COOH hybrid material as an efficient sorbent for trace determination of cadmium and lead ions in water samples.

    Science.gov (United States)

    Nabid, Mohammad Reza; Sedghi, Roya; Behbahani, Mohammad; Arvan, Behnoush; Heravi, Majid M; Oskooie, Hossein Abdi

    2014-07-01

    Poly 1,8-diaminonaphthalene/multiwalled carbon nanotubes-COOH hybrid material as an effective sorbents in solid phase extraction has been developed for the separation and preconcentration of Cd(II) and Pb(II) at trace levels in environmental water samples. The results indicate that the novel nanocomposite show a high affinity for these heavy metals due to the presence of several good extractive sites, which are introduced to the synthesized nanocomposite The maximum adsorption capacity of the synthesized sorbent for cadmium and lead ions was found to be 101.2 and 175.2 mg g(-1) , respectively. The detection limits of this method were 0.09 and 0.7 ng ml(-1) for Cd(II) and Pb(II), respectively.

  6. Planos de amostragem no desenvolvimento inicial do cafeeiro sob irrigação Sampling plans in the initial development of the irrigated coffee

    Directory of Open Access Journals (Sweden)

    Augusto R. de Morais

    2005-12-01

    Full Text Available Este trabalho teve por objetivo avaliar características de plantas de café cultivar Rubi-MG1192 e, através da variabilidade dessas características, estabelecer planos de amostragem para orientar projetos na cultura do café, em desenvolvimento inicial. O experimento está instalado na área experimental do Departamento de Agricultura da Universidade Federal de Lavras, em Lavras, MG. O delineamento experimental foi em blocos casualizados, com quatro repetições, e os tratamentos constam das combinações de densidades de plantio definidas pelos espaçamentos 2500 (4,0 x 1,0 m, 3000 (3,0 x 1,0 m, 5000 (2,0 x 1,0 m, 10000 (2,0 x 0,5 m e 20000 (1,0 x 0,5 m e critérios para início das irrigações (-20, -80, -140 e -200 kPa, manejo SISDA 3-5ò e sem irrigação. Foram estabelecidos vários planos de amostragem para as variáveis altura de planta, diâmetro de caule e diâmetro de copa em função de diferentes números de repetições e de plantas por parcela. Há redução no coeficiente de variação com o aumento do número de plantas por parcela. O diâmetro de caule apresentou maior variabilidade que altura de planta. As estimativas das diferenças mínimas significativas entre duas médias de tratamentos decrescem com aumento do número de repetições e com o aumento do número de plantas por parcela.The objective of this study was to evaluate the characteristics of Rubi MG1192 coffee plant and depending on variability of characteristics establish sampling plans for guidence of projects. The treatments consisted of five densities 2,500 (4.0x1.0 m, 3,000 (3.0x1.0 m, 5,000 (2.0x1.0 m, 10,000 (2.0x0.5 m and 20,000 plants ha-1 (1.0x0.5 m and five irrigation scheduling criteria (-20, -80, -140 and -200 kPa and SISDA3.5ò irrigation scheduler and no irrigation. The planting was accomplished in January, 2001. A completely randomized block design was used with four replications in split-plot. In the main plot were located the plant spacings and

  7. Internet plan and planning

    Directory of Open Access Journals (Sweden)

    Kahriman Emina

    2008-01-01

    Full Text Available Paper discuss specific features of internet plan as well as planning as management process in general in the contemporary environment. No need to stress out that marketing plan and marketing planning is core activity in approaching to market. At the same time, there are a lot specific c request in preparing marketing plan comparing to business planning due to marketing plan is an essential part. The importance of internet plan and planning rely on specific features of the internet network but as a part of general corporate as well as marketing strategy.

  8. Comparison of multiplex PCR hybridization-based and singleplex real-time PCR-based assays for detection of low prevalence pathogens in spiked samples.

    Science.gov (United States)

    Hockman, Donna; Dong, Ming; Zheng, Hong; Kumar, Sanjai; Huff, Matthew D; Grigorenko, Elena; Beanan, Maureen; Duncan, Robert

    2017-01-01

    Molecular diagnostic devices are increasingly finding utility in clinical laboratories. Demonstration of the effectiveness of these devices is dependent upon comparing results from clinical samples tested with the new device to an alternative testing method. The preparation of mock clinical specimens will be necessary for the validation of molecular diagnostic devices when a sufficient number of clinical specimens is unobtainable. Examples include rare pathogens, some of which are pathogens posing a biological weapon threat. Here we describe standardized steps for developers to follow for the culture and quantification of three organisms used to spike human whole blood to create mock specimens. The three organisms chosen for this study were the Live Vaccine Strain (LVS) of Francisella tularensis, surrogate for a potential biothreat pathogen, Escherichia coli, a representative Gram-negative bacterium and Babesia microti (Franca) Reichenow Peabody strain, representing a protozoan parasite. Mock specimens were prepared with blood from both healthy donors and donors with nonspecific symptoms including fever, malaise, and flu-like symptoms. There was no significant difference in detection results between the two groups for any pathogen. Testing of the mock samples was compared on two platforms, Target Enriched Multiplex-PCR (TEM-PCR™) and singleplex real-time PCR (RT-PCR). Results were reproducible on both platforms. The reproducibility demonstrated by obtaining the same results between two testing methods and between healthy and symptomatic mock specimens, indicates the standardized methods described for creating the mock specimens are valid and effective for evaluating diagnostic devices.

  9. 荧光原位杂交技术检测自然流产组织染色体非整倍体%Detection of chromosomal aneuploidies in spontaneous abortion samples by fluorescence in situ hybridization

    Institute of Scientific and Technical Information of China (English)

    魏萍; 李运星; 陈春; 曾兰; 秦胜芳; 汪雪雁; 席娜

    2015-01-01

    目的 探讨荧光原位杂交(fluorescence in situ hybridization,FISH)技术在自然流产组织染色体非整倍体检测中的价值和自然流产患者中染色体非整倍体比例.方法 对81份自然流产组织标本进行13、21和16、22及18、X、Y三组染色体探针的FISH检测.结果 81份自然流产组织中成功标记80份,检测成功率98.77%,其中异常标本35例,异常检出率43.75%,分别为常染色体三体19例,性染色体单体6例,三倍体9例,四倍体1例.结论 FISH技术用于自然流产组织染色体非整倍体分析具有快速、简便等优点,FISH分析可满足染色体非整倍体分析的需要;早期的自然流产病例中染色体非整倍体占较大的比例.%Objective To analyze 81 spontaneous abortion samples with fluorescence in situ hybridization (FISH).Methods Chromosome 13,21,16,22,18,X and Y probes were used to detect the samples.Results FISH was successful in 80 cases (98.77%).Among these,35 (43.75%) had an abnormal karyotype,which included 19 autosomal aneuploidies,6 sex chromosome aneuploidies,9 triploidies and 1 tetraploidy.Conclusion FISH is a rapid and easy method for detecting chromosomal aneuploidies in spontaneous abortion samples,and has a higher detection rate in early spontaneous abortion samples.

  10. Training Faculty to Teach in Hybrid Settings

    Science.gov (United States)

    Linder, Kathryn E.

    2017-01-01

    Based on the author's experiences developing and implementing a multi-week hybrid course design institute, this chapter outlines the components of training--both andragogical and technological--most helpful for faculty who are planning to teach a hybrid course.

  11. Hybrid Metaheuristics

    CERN Document Server

    2013-01-01

    The main goal of this book is to provide a state of the art of hybrid metaheuristics. The book provides a complete background that enables readers to design and implement hybrid metaheuristics to solve complex optimization problems (continuous/discrete, mono-objective/multi-objective, optimization under uncertainty) in a diverse range of application domains. Readers learn to solve large scale problems quickly and efficiently combining metaheuristics with complementary metaheuristics, mathematical programming, constraint programming and machine learning. Numerous real-world examples of problems and solutions demonstrate how hybrid metaheuristics are applied in such fields as networks, logistics and transportation, bio-medical, engineering design, scheduling.

  12. Health and Safety Work Plan for Sampling Colloids in Waste Area Grouping 5 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, J.D.; McCarthy, J.F.

    1994-01-01

    This Work Plan/Site Safety and Health Plan (SSHP) and the attached work plan are for the performance of the colloid project at WAG 5. The work will be conducted by the Oak Ridge National Laboratory (ORNL) Environmental Sciences Division (ESD) and associated ORNL environmental, safety, and health support groups. The purpose of this document is to establish health and safety guidelines to be followed by all personnel involved in conducting work for this project. The levels of protection and the procedures specified in this plan are based on the best information available from historical data and preliminary evaluations of the area. Therefore, these recommendations represent the minimum health and safety requirements to be observed by all personnel engaged in this project.

  13. pH-resistant titania hybrid organic-inorganic coating for stir bar sorptive extraction of drugs of abuse in urine samples followed by high performance liquid chromatography-ultraviolet visible detection.

    Science.gov (United States)

    Lan, Lidan; Hu, Bin; Yu, Chunhe

    2010-11-05

    An organic-inorganic hybrid titania-hydroxy-terminated silicone oil (titania-OH-TSO) stir bar coating was prepared by sol-gel method. The extraction performance of titania-OH-TSO coated stir bar was evaluated and compared with poly(dimethysiloxane) (PDMS), poly(dimethysiloxane)-divinylbenzene (PDMS-DVB), poly(dimethysiloxane)-β-cyclodextrin (PDMS-β-CD) and C(18) coated stir bar with five polar drugs of abuse including amphetamine (PA), methamphetamine (MA), 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA) and ketamine (Ke) as the model analytes. The experimental results revealed that the titania-OH-TSO coated stir bar exhibited highly pH-resistant ability, good preparation reproducibility, superior selectivity and high extraction efficiency for the target compounds. Based on this fact, a new method of titania-OH-TSO coated stir bar sorptive extraction (SBSE) combined with high performance liquid chromatography (HPLC)-ultraviolet visible (UV) detection was developed for the analysis of five drugs of abuse in urine samples. The factors affecting the extraction efficiency of SBSE such as sample pH, desorption solvent, sample volume, extraction time, desorption time, stirring rate and ionic strength were investigated and the optimal extraction conditions were established. Under the optimized conditions, the limits of detection (LODs) for titania-OH-TSO coated SBSE-HPLC-UV determination of five polar drugs of abuse were in the range of 2.3-9.1 μg/L with relative standard deviations (RSDs) ranging from 7.3 to 8.9% (c=300 μg/L, n=6), and all of the target compounds exhibited good linearity over a concentration range of 30-3000 μg/L. The developed method was applied to the determination of amphetamines and Ke in urine samples of drug abusers with satisfactory results.

  14. Probabilistic short-circuit analysis of wind power systems with multiple contingencies and hybrid sampling%基于多重故障和混合仿真算法的风电系统概率短路分析

    Institute of Scientific and Technical Information of China (English)

    李生虎; 钱壮; 黄杰杰; 董王朝

    2015-01-01

    Multiple-contingency and wind power integration add difficulty for probabilistic short-circuit analysis (PSCA). The power flow model with doubly-fed induction generators (DFIGs) is introduced, which together with wind uncertainty yields initial state before contingency. The multiple-contingency algorithm is introduced to find expectation, variance, and distribution of the bus voltages and the branch currents. A hybrid probabilistic sampling technique is proposed with the fault branch enumerated and probabilistically weighted, and other fault parameters sampled. The variance for the hybrid simulation is proposed by combined analytical enumeration and probabilistic sampling. Numerical analysis quantifies impact of wind fluctuation and double contingencies on the PSCA results, and compares convergence of sequential voltages and currents. The proposed models provide reference to select electrical equipment and analyze power system security.%多重故障、风电并网增加了概率短路计算难度。引入双馈风电机组潮流算法,计及风速不确定性,得到概率短路前初始运行方式。引入多重短路算法,计算节点电压和支路电流的期望、方差以及概率分布。对枚举故障线路进行概率加权,抽样确定其他故障参数,建立混合仿真算法。综合考虑解析枚举和概率抽样特点,提出混合概率仿真方差计算公式。算例分析对比了风电出力波动、双重短路对概率短路计算结果的影响,比较了三序电压和电流的收敛性。研究结果为电气设备选择和电网安全分析提供了参考数据。

  15. Hybrid intermediaries

    OpenAIRE

    Cetorelli, Nicola

    2014-01-01

    I introduce the concept of hybrid intermediaries: financial conglomerates that control a multiplicity of entity types active in the "assembly line" process of modern financial intermediation, a system that has become known as shadow banking. The complex bank holding companies of today are the best example of hybrid intermediaries, but I argue that financial firms from the "nonbank" space can just as easily evolve into conglomerates with similar organizational structure, thus acquiring the cap...

  16. Hybrid composites

    CSIR Research Space (South Africa)

    Jacob John, Maya

    2009-04-01

    Full Text Available effect was observed for the elongation at break of the hybrid composites. The impact strength of the hybrid composites increased with the addition of glass fibres. The tensile and impact properties of thermoplastic natural rubber reinforced short... panels made from conventional structural materials. Figure 3 illustrates the performance of cellular biocomposite panels against conventional systems used for building and residential construction, namely a pre- cast pre-stressed hollow core concrete...

  17. Speciation of As(III)/As(V) in water samples by a magnetic solid phase extraction based on Fe₃O₄/Mg-Al layered double hydroxide nano-hybrid followed by chemiluminescence detection.

    Science.gov (United States)

    Abdolmohammad-Zadeh, Hossein; Talleb, Zeynab

    2014-10-01

    A novel magnetic solid phase extraction method was developed for the speciation of As(III)/As(V) in aqueous solutions utilizing Fe3O4-doped Mg-Al layered double hydroxide (LDH) as a nano-sorbent. The method is based on the separation and pre-concentration of As(V) by Fe3O4/Mg-Al LDH nano-hybrid prior to determination by a chemiluminescence (CL) technique. The CL route involves the oxidation of luminol by vanadomolybdoarsenate heteropoly acid in a basic media. Since the existing cations cannot be adsorbed by positively charged layers of the LDH and other potentially interferent anions had no considerable effect on the CL reaction, it provides a very selective and sensitive determination approach for As(V). The determination of total arsenic and hence indirectly As(III) involve the pre-oxidation of As(III) to As(V) by a mixture of hydrogen peroxide and potassium hydroxide. Several factors affecting the extraction and determination of the analyte were investigated and optimized. Under optimum conditions, the calibration graph was linear in the range of 5.0-5000 ng L(-1). The limit of detection and enrichment factor was 2.0 ng L(-1) and 80, respectively. The method was validated by the analysis of a standard reference material (NIST SRM 1643e), and successfully applied to the speciation of arsenic in several water samples with recoveries in the range of 93.3-106.7% for the spiked samples.

  18. Correlates of physical activity in a population-based sample of kidney cancer survivors: an application of the theory of planned behavior.

    Science.gov (United States)

    Trinh, Linda; Plotnikoff, Ronald C; Rhodes, Ryan E; North, Scott; Courneya, Kerry S

    2012-08-06

    Over half of kidney cancer survivors (KCS) are completely inactive and only a quarter are meeting physical activity (PA) guidelines. This highlights the need to identify and understand the determinants of PA in this understudied population. The purpose of this study is to determine the social cognitive correlates of PA intention and behavior in KCS using the Theory of Planned Behavior (TPB). All 1,985 KCS diagnosed between 1996 and 2010 in Alberta, Canada were mailed a self-report survey that consisted of the Godin Leisure Time Exercise Questionnaire and standard TPB items for intention, planning, perceived behavioral control (PBC), affective and instrumental attitudes, and descriptive and injunctive norms. Standard demographic and medical variables were also collected. Completed surveys were received from 703 of 1,654 (43%) eligible KCS. The TPB was tested using structural equation modelling and demonstrated an adequate-to-good fit to the data [χ² = 256.88, p planning (ß = 0.22, p planning from intention (ß = 0.81, p planning and PA, respectively. The TPB appears to be a useful model for explaining PA in KCS. All TPB constructs except injunctive norm and affective attitude were useful for explaining intention with PBC emerging as the largest correlate. Developing PA interventions based on the TPB may be effective in promoting PA in KCS and may lead to important improvements in health.

  19. Experimental Design for the INL Sample Collection Operational Test

    Energy Technology Data Exchange (ETDEWEB)

    Amidan, Brett G.; Piepel, Gregory F.; Matzke, Brett D.; Filliben, James J.; Jones, Barbara

    2007-12-13

    for detecting contamination or clearing uncontaminated (or decontaminated) areas. Following sample collection for a given test event, the INL building will be decontaminated using Cl2O gas. For possibly contaminated areas (individual rooms or the whole floor of a building), the numbers of probabilistic samples were chosen to provide 95% confidence of detecting contaminated areas of specified sizes. The numbers of judgmental samples were chosen based on guidance from experts in judgmental sampling. For rooms that may be uncontaminated following a contamination event, or for whole floors after decontamination, the numbers of judgmental and probabilistic samples were chosen using a Bayesian approach that provides for combining judgmental and probabilistic samples to make a clearance statement of the form “95% confidence that at least 99% of the room (or floor) is not contaminated”. The experimental design also provides for making 95%/Y% clearance statements using only probabilistic samples, where Y < 99. For each test event, the numbers of samples were selected for a minimal plan (containing fewer samples) and a preferred plan (containing more samples). The preferred plan is recommended over the minimal plan. The preferred plan specifies a total of 1452 samples, 912 after contamination and 540 after decontamination. The minimal plan specifies a total of 1119 samples, 744 after contamination and 375 after decontamination. If the advantages of the “after decontamination” portion of the preferred plan are judged to be small compared to the “after decontamination” portion of the minimal plan, it is an option to combine the “after contamination” portion of the preferred plan (912 samples) with the “after decontamination” portion of the minimal plan (375 samples). This hybrid plan would involve a total of 1287 samples.

  20. Gendered Motivational Processes Affecting High School Mathematics Participation, Educational Aspirations, and Career Plans: A Comparison of Samples from Australia, Canada, and the United States

    Science.gov (United States)

    Watt, Helen M. G.; Shapka, Jennifer D.; Morris, Zoe A.; Durik, Amanda M.; Keating, Daniel P.; Eccles, Jacquelynne S.

    2012-01-01

    In this international, longitudinal study, we explored gender differences in, and gendered relationships among, math-related motivations emphasized in the Eccles (Parsons) et al. (1983) expectancy-value framework, high school math participation, educational aspirations, and career plans. Participants were from Australia, Canada, and the United…

  1. From hybrid-media system to hybrid-media politicians

    DEFF Research Database (Denmark)

    Eberholst, Mads Kæmsgaard; Ørsten, Mark; Burkal, Rasmus

    2017-01-01

    An increasingly complex hybrid system of social- and traditional-news media surrounds Nordic election campaigns as politically experienced incumbents favour traditional news media, and younger, lesser-known candidates’ social media. Despite little evidence for hybrid-media politicians, politicians......’ media use is changing rapidly; 15%–16% of Danish candidates used Twitter in 2011 but 68% in 2015. In this large-sample content analysis, party leaders have high traditional-news-media and low Twitter presence, and younger candidates visa-versa, but some politicians have high presence in both. Hybrid...

  2. Sampling Plan Design of the Survey on Satisfactory Degree to Shandong TV Audience%山东电视观众满意度调查抽样方案设计

    Institute of Scientific and Technical Information of China (English)

    俞纯权

    2001-01-01

    The thesis gives the sampling plan design of the survey on satisfactory degree to Shandong TV audience,constructs estimators of two kinds of objectiue value and analyses their precision.%本文给出山东电视观众满意度调查的抽样方案设计,构造了两类目标量的估计量,并对估计量的精度进行了分析。

  3. 一种混合驱动柔索并联仿生眼的轨迹规划%Trajectory Planning of a Bionic Eye Using Hybrid-Driven Cable Parallel Mechanism

    Institute of Scientific and Technical Information of China (English)

    谢少荣; 刘思淼; 罗均; 黄潮炯; 杨毅; 李恒宇

    2015-01-01

    在与眼球运动相关的解剖学和运动学的基础上,设计了一种符合Listing定理的基于混合驱动柔索并联机构的3自由度机器人仿生眼。通过矢量封闭方法建立了逆运动学模型,求解出柔索并联机器人的雅可比矩阵和结构矩阵。利用达朗贝尔定理建立柔索并联机器人的力矩平衡方程组,采用广义逆矩阵的相关理论,以柔索张力矢量的2范数最小为目标进行张力优化。用蒙特卡洛方法计算出仿生眼球可达工作空间。最后,在Simulink环境下进行仿真,规划运动轨迹并得到柔索并联机器人运动特性的仿真结果,证明了本文设计的机构符合Listing定理。结果表明:基于混合驱动柔索并联机构的机器人仿生眼结构合理,数学模型正确。%Based on anatomy and kinematics of human’s eyeball, a 3-DOF (degree of freedom) bionic eye with hybrid-driven cable parallel mechanism (CPM) is presented according to Listing’s law. An inverse kinematics model is built with the vector closure method, and Jacobian matrices and structure matrices of CPMs are solved. Force moment equilibrium equations of CPMs are established based on Darren Bell’s theorem. With the aim of minimizing the 2-norm of cable tension vectors, tension distribution is optimized according to generalized inverse matrix theories. The reachable work space of the bionic eye is calculated with Monte-Carlo method. Finally, the trajectories of CPMs are planned in Simulink environment, the corresponding kinematic performance results are obtained, and the designed mechanism is proven to be in accordance with Listing’s law. The result shows that the bionic eye using hybrid-driven CPM is reasonable, and the derived mathematical models are correct.

  4. Fiscal year 1980-81 implementation plan in support of technical development and integration of sampling and aggregation procedures. [crop acreage estimation

    Science.gov (United States)

    1981-01-01

    The specific objectives of the FY 1980-81 tasks are: (1) further refinements to the weighted aggregation procedure; (2) improved approaches for estimating within-stratum variance; (3) more intensive investigation of alternative sampling strategies such as full-frame sampling strategy, and (4) further developments in regard to a simulated approach for assessing the performance of the overall designed sampling and aggregation system.

  5. Sampling-based real-time motion planning under state uncertainty for autonomous micro-aerial vehicles in GPS-denied environments.

    Science.gov (United States)

    Li, Dachuan; Li, Qing; Cheng, Nong; Song, Jingyan

    2014-11-18

    This paper presents a real-time motion planning approach for autonomous vehicles with complex dynamics and state uncertainty. The approach is motivated by the motion planning problem for autonomous vehicles navigating in GPS-denied dynamic environments, which involves non-linear and/or non-holonomic vehicle dynamics, incomplete state estimates, and constraints imposed by uncertain and cluttered environments. To address the above motion planning problem, we propose an extension of the closed-loop rapid belief trees, the closed-loop random belief trees (CL-RBT), which incorporates predictions of the position estimation uncertainty, using a factored form of the covariance provided by the Kalman filter-based estimator. The proposed motion planner operates by incrementally constructing a tree of dynamically feasible trajectories using the closed-loop prediction, while selecting candidate paths with low uncertainty using efficient covariance update and propagation. The algorithm can operate in real-time, continuously providing the controller with feasible paths for execution, enabling the vehicle to account for dynamic and uncertain environments. Simulation results demonstrate that the proposed approach can generate feasible trajectories that reduce the state estimation uncertainty, while handling complex vehicle dynamics and environment constraints.

  6. Correlates of physical activity in a population-based sample of kidney cancer survivors: an application of the theory of planned behavior

    Directory of Open Access Journals (Sweden)

    Trinh Linda

    2012-08-01

    Full Text Available Abstract Background Over half of kidney cancer survivors (KCS are completely inactive and only a quarter are meeting physical activity (PA guidelines. This highlights the need to identify and understand the determinants of PA in this understudied population. The purpose of this study is to determine the social cognitive correlates of PA intention and behavior in KCS using the Theory of Planned Behavior (TPB. Methods All 1,985 KCS diagnosed between 1996 and 2010 in Alberta, Canada were mailed a self-report survey that consisted of the Godin Leisure Time Exercise Questionnaire and standard TPB items for intention, planning, perceived behavioral control (PBC, affective and instrumental attitudes, and descriptive and injunctive norms. Standard demographic and medical variables were also collected. Results Completed surveys were received from 703 of 1,654 (43% eligible KCS. The TPB was tested using structural equation modelling and demonstrated an adequate-to-good fit to the data [χ² = 256.88, p  There were significant pathways to PA from PBC (ß = 0.18, p = 0.02, planning (ß = 0.22, p  Conclusion The TPB appears to be a useful model for explaining PA in KCS. All TPB constructs except injunctive norm and affective attitude were useful for explaining intention with PBC emerging as the largest correlate. Developing PA interventions based on the TPB may be effective in promoting PA in KCS and may lead to important improvements in health.

  7. STEP-NC oriented process planning optimization based on hybrid genetic algorithm%面向STEP-NC基于混合式遗传算法的工艺路线优化

    Institute of Scientific and Technical Information of China (English)

    欧阳华兵; 沈斌

    2012-01-01

    为适应STEP-NC技术的发展需求,解决基于STEP-NC非线性工艺路线优化问题,在深入分析STEP-NC基于加工特征的数据模型基础上,探讨了工艺路线优化中存在的问题及其相关约束,提出采用基于操作优先图的智能搜索与遗传算法相结合的混合式算法。首先考虑加工操作排序中的强制性约束,采用基于操作优先图的智能搜索算法,获取多个可行的加工操作顺序,并将其作为遗传算法的初始化种群;然后综合考虑机床选择、刀具选择和刀具运动方向选择,以加工成本最低为目标函数,根据优化约束条件,通过遗传算法的复制、交叉和变异等操作实现有效工艺路线的优化决策,得到满足车间要求的最优或接近最优的工艺路线。通过实例,验证了该算法在面向STEP-NC加工特征的零件工艺路线优化上的可行性和有效性。%To meet the requirements of STEP-NC technology and to solve the non-linear process planning problem,the existing problems in process planning optimization and its related constraints were discussed on the basis of analyzing STEP-NC data model based on machining features.The hybrid algorithm was proposed by integrating intelligent search of operation precedence graph with genetic algorithm.The compulsive constraints were firstly considered in the sequence of operations,and the alternative operation sequences were acquired by intelligent search algorithm based on operation precedence graph.This algorithm was acted as the initial population for the next genetic algorithm.The selections of machine tool,tool and tool approach direction were all taken into account,by taking the lowest machining cost as optimization objective function,the effective process planning optimization decision was achieved through operation of genetic algorithm's copy,cross and variation according to optimization constraints.The optimal or near optimal process route which satified the workshop

  8. Novel hybrid carrier tracking loop in the case of symbol rate sampling%符号速率采样条件下的新型复合载波跟踪环

    Institute of Scientific and Technical Information of China (English)

    李运华; 田斌; 易克初; 于全; 孙德春

    2016-01-01

    For carrier synchronization in the case of symbol rate sampling and low signal to noise ratios (SNRs),a novel hybrid carrier tracking loop is proposed,and an intuitive method of determining loop parame-ters is also investigated.The carrier synchronous loop improves the estimated accuracy of the carrier frequency offset and the phase offset in low SNR environments through modifying the original symbol hard decision meth-od and adding sampling rate conversion blocks which enable the digital frequency-locked loop (FLL)and digital phase-locked loop (PLL)to operate under the condition of different rate sampling.The parameter determination method selects optimal parameters in the z-domain directly according to the stability and unit step response characteris-tics of the closed-loop systems.Simulation results confirm the feasibility of this algorithm in terms of determi-ning the parameters and indicate that the proposed carrier tracking loop achieves better synchronization perform-ance at relatively low SNRs.%针对低信噪比和符号速率采样条件下的载波同步问题,提出了一种新型的复合载波跟踪环,同时也给出了一种较直观的环路参数确定方法。该载波同步环改进了原有的符号硬判决算法,并通过引入采样速率变换模块使得数字锁频环(frequency-locked loop,FLL)和数字锁相环(phase-locked loop,PLL)工作在不同采样速率条件下,来提高在低信噪比环境中载波频偏和相偏的估计精度。该参数确定方法是在 z 域中,直接根据闭环系统的稳定性和单位阶跃响应特性来选择最优的参数。仿真结果表明,该参数确定方法具有很好的可行性,且所提出的载波跟踪环在较低信噪比条件下能获得良好的同步性能。

  9. 荧光原位杂交法(FISH)快速检测尿液中金黄色葡萄球菌%Fluorescence in Situ Hybridization Rapidly Detects Staphylococcus Aureus in Urinary Tract Infection Samples

    Institute of Scientific and Technical Information of China (English)

    吴青; 李艳; 汪明; 顾剑; 胡慧霞; 徐万洲; 韦传东; 吴泽刚

    2011-01-01

    目的 利用荧光原位杂交法快速检测尿液中的金黄色葡萄球菌,筛查金黄色葡萄球菌所致的尿路感染.方法 针对金黄色葡萄球菌16sRNA设计荧光标记的核苷酸探针,利用荧光原位杂交技术(FISH)对132例疑似尿路感染患者中段尿标本进行检测;同时进行中段尿培养.结果 荧光原位杂交法检测阳性的有9例,与中段尿培养比较,其敏感度为100.0%,特异度为99.2%,阳性预期值为90.0%,阴性预期值为100.0%.结论 荧光原位杂交能快速检测尿液中的金黄色葡萄球菌,对金黄色葡萄球菌所致的尿路感染进行快速诊断.%Objective The rapid detection of Staphylococcus aureus in urine by fluorescence in situ hybridization (FISH)method. Screening urinary tract infection (UTIs) caused by Staphylococcus aureus. Methods Probes that were specific for Staphylococcus aureus were designed based on the conserved 16 s RNA sequences. Detected a total of 132 urine samples using FISH method. And all of tbese samples tested via traditional culturing techniques. Results 9 of these samples tested positive for a UTI via FISH analysis. Compared to conventional methods of bacterial identification,the FISH method had a sensitivity of 100.0% ,specificity of 99. 2%,positive expected value of 90. 0% and negative expected value of 100. 0%. Conclusion FISH had the potential to become an extremely useful diagnostic tool for UTIs because it has a quick turnaround time and high accuracy.

  10. Routine Radiological Environmental Monitoring Plan, Volume 2 Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel Nevada

    1998-12-31

    Supporting material for the plan includes: QUALITY ASSURANCE, ANALYSIS, AND SAMPLING PLAN FOR NTS AIR; QUALITY ASSURANCE, ANALYSIS, AND SAMPLING PLAN FOR WATER ON AND OFF THE NEVADA TEST SITE; QUALITY ASSURANCE, ANALYSIS, AND SAMPLING PLAN FOR NTS BIOTA; QUALITY ASSURANCE, ANALYSIS, AND SAMPLING PLAN FOR DIRECT RADIATION MONITORING; DATA QUALITY OBJECTIVES PROCESS; VADOSE ZONE MONITORING PLAN CHECKLIST.

  11. Probabilistic Hybrid Action Models for Predicting Concurrent Percept-driven Robot Behavior

    CERN Document Server

    Beetz, M; 10.1613/jair.1565

    2011-01-01

    This article develops Probabilistic Hybrid Action Models (PHAMs), a realistic causal model for predicting the behavior generated by modern percept-driven robot plans. PHAMs represent aspects of robot behavior that cannot be represented by most action models used in AI planning: the temporal structure of continuous control processes, their non-deterministic effects, several modes of their interferences, and the achievement of triggering conditions in closed-loop robot plans. The main contributions of this article are: (1) PHAMs, a model of concurrent percept-driven behavior, its formalization, and proofs that the model generates probably, qualitatively accurate predictions; and (2) a resource-efficient inference method for PHAMs based on sampling projections from probabilistic action models and state descriptions. We show how PHAMs can be applied to planning the course of action of an autonomous robot office courier based on analytical and experimental results.

  12. Hybrid microelectronic technology

    Science.gov (United States)

    Moran, P.

    Various areas of hybrid microelectronic technology are discussed. The topics addressed include: basic thick film processing, thick film pastes and substrates, add-on components and attachment methods, thin film processing, and design of thick film hybrid circuits. Also considered are: packaging hybrid circuits, automating the production of hybrid circuits, application of hybrid techniques, customer's view of hybrid technology, and quality control and assurance in hybrid circuit production.

  13. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    Energy Technology Data Exchange (ETDEWEB)

    Frazier, T.P.

    1994-10-20

    This Quality Assurance Project Plan addresses the quality assurance requirements for the activities associated with the Facility Effluent Monitoring Plans, which are part of the overall Hanford Site Environmental Protection Plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of the individual Facility Effluent Monitoring Plans.

  14. Soil Sampling and Analysis Plan for the McGee Ranch-Riverlands and North Slope Units of the Hanford Reach National Monument

    Energy Technology Data Exchange (ETDEWEB)

    Fritz, Brad G.; Dirkes, Roger L.

    2004-12-27

    This document describes soil sampling that will be performed by Pacific Northwest National Laboratory's Surface Environmental Surveillance Project on two units of the Hanford Reach National Monument: the McGee Ranch-Riverlands Unit (Riverlands Unit) and the North Slope made up of the Saddle Mountain Unit and the Wahluke Slope Unit. This sampling fulfills a U.S. Department of Energy requirement to evaluate the potential for residual radioactive contamination on this land and determine compliance with the requirements of DOE Order 5400.5 prior to radiological release of the property.

  15. Using the Theory of Planned Behavior to identify key beliefs underlying chlamydia testing intentions in a sample of young people living in deprived areas.

    Science.gov (United States)

    Booth, Amy R; Norman, Paul; Harris, Peter R; Goyder, Elizabeth

    2015-09-01

    The Theory of Planned Behavior was used to identify the key behavioural, normative and control beliefs underlying intentions to test regularly for chlamydia among young people living in socially and economically deprived areas - a high-risk group for infection. Participants (N = 278, 53% male; mean age 17 years) were recruited from a vocational college situated in an area in the most deprived national quintile (England). Participants completed measures of behavioural, normative and control beliefs, plus intention to test regularly for chlamydia. The behavioural, normative and control beliefs most strongly correlated with intentions to test regularly for chlamydia were beliefs about stopping the spread of infection, partners' behaviour and the availability of testing. These beliefs represent potential targets for interventions to increase chlamydia testing among young people living in deprived areas.

  16. Sampling and analysis plan for treatment water and creek water for the Lower East Fork Poplar Creek Operable Unit, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This document provides the Environmental Restoration Program with information about the methodology, organizational structure, quality assurance and health and safety practices to be employed during the water sampling and analysis activities associated with the remediation of the Lower East Fork Poplar Creek Operable Unit during remediation of the National Oceanic and Atmospheric Administration and Bruner sites.

  17. Improvement of sampling plans for Salmonella detection in pooled table eggs by use of real-time PCR

    DEFF Research Database (Denmark)

    Pasquali, Frédérique; De Cesare, Alessandra; Valero, Antonio

    2014-01-01

    mixed with one contaminated egg) and contamination levels (10°-10(1), 10(1)-10(2), 10(2)-10(3)CFU/eggshell). Two hundred and seventy samples corresponding to 15 replicates per pool size and inoculum level were tested. At the lowest contamination level real-time PCR detected Salmonella in 40...

  18. Sampling plan for the analysis of aflatoxin in peanuts and corn: an update Sistema de amostragem para análise de aflatoxinas em amendoim e milho: uma atualização

    Directory of Open Access Journals (Sweden)

    Homero Fonseca

    2002-06-01

    Full Text Available The aim of this paper was to update the sampling plan for analysis of mycotoxins in grains, formerly published by the author. The proposed alterations were based on the acquired experience on its application and on FAO recommendations. This update restricts the scope of the former plan and establishes a sampling plan for analysis of aflatoxin in peanuts and corn, by means of modified formulas, the minimum number of sacks or points (when in bulk from which incremental samples should be drawn to make a bulk sample. Fractional exponents (square roots of the formulas proportionally decrease the number of sacks/points to be sampled as the lot size increases. Operating Characteristic (OC curves developed for in-shell and shelled peanuts and corn as well as trend curves of the coefficient variation for different sample sizes (weights are presented.O objetivo deste trabalho foi atualizar a metodologia de amostragem para análise de micotoxinas em grãos, anteriormente publicada pelo autor. As alterações propostas tiveram por base a experiência adquirida na sua utilização e em recomendações da FAO. Esta atualização restringe a aplicação do método anterior e estabelece um plano de amostragem para análise de aflatoxina em amendoim e em milho por meio de fórmulas modificadas, o mínimo de sacos ou pontos (quando a granel dos quais devem ser retiradas amostras incrementais para constituir uma amostra. Expoentes fracionários (raiz quadrada das fórmulas diminuem proporcionalmente o número de sacos/pontos a serem amostrados, à medida que o lote aumenta de tamanho. Curvas de operação característica (OC desenvolvidas para amendoim em casca e descascado e milho, bem como curvas de tendência dos coeficientes de variação, para diferentes tamanhos de amostra (peso, são apresentadas.

  19. Hybrid Gear

    Science.gov (United States)

    Handschuh, Robert F. (Inventor); Roberts, Gary D. (Inventor)

    2016-01-01

    A hybrid gear consisting of metallic outer rim with gear teeth and metallic hub in combination with a composite lay up between the shaft interface (hub) and gear tooth rim is described. The composite lay-up lightens the gear member while having similar torque carrying capability and it attenuates the impact loading driven noise/vibration that is typical in gear systems. The gear has the same operational capability with respect to shaft speed, torque, and temperature as an all-metallic gear as used in aerospace gear design.

  20. Hybrid Qualifications

    DEFF Research Database (Denmark)

    has turned out as a major focus of European education and training policies and certainly is a crucial principle underlying the European Qualifications Framework (EQF). In this context, «hybrid qualifications» (HQ) may be seen as an interesting approach to tackle these challenges as they serve «two...... masters», i.e. by producing skills for the labour market and enabling individuals to progress more or less directly to higher education. The specific focus of this book is placed on conditions, structures and processes which help to combine VET with qualifications leading into higher education...

  1. Stochastic Reachability Analysis of Hybrid Systems

    CERN Document Server

    Bujorianu, Luminita Manuela

    2012-01-01

    Stochastic reachability analysis (SRA) is a method of analyzing the behavior of control systems which mix discrete and continuous dynamics. For probabilistic discrete systems it has been shown to be a practical verification method but for stochastic hybrid systems it can be rather more. As a verification technique SRA can assess the safety and performance of, for example, autonomous systems, robot and aircraft path planning and multi-agent coordination but it can also be used for the adaptive control of such systems. Stochastic Reachability Analysis of Hybrid Systems is a self-contained and accessible introduction to this novel topic in the analysis and development of stochastic hybrid systems. Beginning with the relevant aspects of Markov models and introducing stochastic hybrid systems, the book then moves on to coverage of reachability analysis for stochastic hybrid systems. Following this build up, the core of the text first formally defines the concept of reachability in the stochastic framework and then...

  2. 连铸组中间包问题的MTSP模型及混合优化算法%Hybrid Optimization Algorithm for Solving Combining Tundish MTSP Model on Continuous Casting Plan

    Institute of Scientific and Technical Information of China (English)

    易剑; 谭树彬; 李维刚; 杜斌

    2012-01-01

    针对连铸计划中的组中间包问题,建立了多旅行商问题(MTSP)模型,提出了一种结合启发式、k-opt邻域搜索和EDA进化的混合优化算法.该算法首先利用启发式规则确定虚拟炉次的个数,从而确定染色体编码长度,每个染色体代表一种中包组合方案,然后设计了基于概率矩阵模型的EDA进化算法对染色体进行全局寻优,并使用k-opt邻域搜索进行局部优化.EDA算法不需要设计如遗传算法(GA)那样的交叉算子,避免了交叉导致的编码非法性问题.通过对企业实际生产数据进行仿真计算,其结果表明了算法具有良好的优化性能和实用性.%The combining tundish problem on continuous casting plan was described and the multiple traveling salesman problem (MTSP) model was constructed. A hybrid optimization algorithm composed of the heuristic method, the k-opt neighborhood search, and the estimation of distribution algorithms (EDA) was proposed to solve the model. First, a heuristic method was used to determine the counts of dummy furnace which were involved in chromosome code to fix on the code length. Each chromosome presented a scheme of combining tundish and then the probability matrix model of the EDA was designed to optimize chromosome globally. Moreover, the k-opt was used as local search strategy. Unlike genetic algorithm(GA), the EDA had no crossover operator, therefore the illegal code resulted from crossover operator was avoided. Simulation results on the real production data indicated that the proposed algorithm had fairly good performance and utility.

  3. Correlates of exercise motivation and behavior in a population-based sample of endometrial cancer survivors: an application of the Theory of Planned Behavior

    Directory of Open Access Journals (Sweden)

    Dundas George

    2007-05-01

    Full Text Available Abstract Background Despite evidence of the benefits of exercise in cancer survivors, exercise participation rates tend to decline after treatments. Few studies have examined the determinants of exercise in less common cancer sites. In this study, we examined medical, demographic, and social cognitive correlates of exercise in endometrial cancer survivors using the Theory of Planned Behavior (TPB. Methods A mailed survey was completed by 354 endometrial cancer survivors (1 to 10 years postdiagnosis residing in Alberta, Canada. The study was cross-sectional. Exercise behavior was assessed using the Godin Leisure Time Exercise Questionnaire and the TPB constructs were assessed with standard self-report scales. Multiple regression analyses were used to determine the independent associations of the TPB constructs with intention and behavior. Results Chi-square analyses indicated that marital status (p = .003, income level (p = .013, and body mass index (BMI (p = .020 were associated with exercise. The TPB explained 34.1% of the variance in exercise behavior with intention (β = .38, p β = .18, p = .029 being independent correlates. For intention, 38.3% of the variance was explained by the TPB with self-efficacy (β = .34, p β = .30, p Conclusion The TPB may be a useful framework for understanding exercise in endometrial cancer survivors. Exercise behavior change interventions based on the TPB should be tested in this growing population.

  4. Computer code for intraply hybrid composite design

    Science.gov (United States)

    Chamis, C. C.; Sinclair, J. H.

    1981-01-01

    A computer program has been developed and is described herein for intraply hybrid composite design (INHYD). The program includes several composite micromechanics theories, intraply hybrid composite theories and a hygrothermomechanical theory. These theories provide INHYD with considerable flexibility and capability which the user can exercise through several available options. Key features and capabilities of INHYD are illustrated through selected samples.

  5. Spatial distributions of the red palm mite, Raoiella indica (Acari: Tenuipalpidae) on coconut and their implications for development of efficient sampling plans

    DEFF Research Database (Denmark)

    Roda, A.; Nachman, G.; Hosein, F.

    2012-01-01

    The red palm mite (Raoiella indica), an invasive pest of coconut, entered the Western hemisphere in 2004, then rapidly spread through the Caribbean and into Florida, USA. Developing effective sampling methods may aid in the timely detection of the pest in a new area. Studies were conducted...... to provide and compare intra tree spatial distribution of red palm mite populations on coconut in two different geographical areas, Trinidad and Puerto Rico, recently invaded by the mite. The middle stratum of a palm hosted significantly more mites than fronds from the upper or lower canopy and fronds from...

  6. Hybrid Warfare

    Science.gov (United States)

    2013-08-01

    Air and Space Studies, Air University and JSOU Associate Fellow William W. Mendel Colonel, U.S. Army, Ret. JSOU Senior Fellow Alvaro de Souza... Gregor , “Military Planning Systems and Stability Operations,” Prism 1, no. 3 (June 2010). Gregor’s analysis is an even account regarding the role of

  7. Application of fluorescence in situ hybridization in rapid prenatal diagnosis of chromosome aneuploidy in uncultured amniotic fluid samples%FISH技术在产前诊断胎儿染色体数异常中的应用

    Institute of Scientific and Technical Information of China (English)

    张利平; 剡红民; 秦翠云; 娄超; 马晓萍; 郑军; 强荣

    2011-01-01

    目的 探讨荧光原位杂交(FISH)技术在快速产前诊断胎儿染色体非整倍体异常中的价值.方法 使用荧光原位杂交技术,选用荧光素标记的双色13/21染色体位点特异性探针和三色18/X/Y染色体着丝粒探针,检测760例胎儿羊水细胞.结果 采用双色13/21号和三色18/X/Y染色体荧光探针检测间期未培养羊水细胞,发现8例21三体综合征,1例13三体综合征,1例45,XO,1例47,XXX,3例性染色体嵌合体.荧光原位杂交检测结果 和常规细胞遗传学检测结果 相比,两者符合率为99%.结论 荧光原位杂交技术在产前快速诊断胎儿染色体非整倍体异常有很高的临床价值.%Objective To investgate clinical value of fluorescence in situ hybridization (FISH) in rapid prenatal diagnosis of chromosome aneuploidy of the fetus. Methods Fluorescein-labeled bicolor 13th/21th chromosomal loci specificity probe and triad colour 18th/X/Y kinomere probe were used to detect cells in uncultured amniotic fluid samples of 760 pregnact women. Results 8 fetuses with trisomy 21 syndrome, I fetus with trisomy 13 syndrome, I fetus with with 45 ,XO, 1 fetus with 47,XXX and 5 fetuses with sex chromosome mosaic syndrome were identified. The coincidence rate of diagnosis between FISH and conventional cytogenetics was 99%. Conclusion FISH technique has a high clinic value in rapid diagnosis of chromosome aneuploidy.

  8. Consensus of Hybrid Multi-Agent Systems.

    Science.gov (United States)

    Zheng, Yuanshi; Ma, Jingying; Wang, Long

    2017-01-27

    In this brief, we consider the consensus problem of hybrid multiagent systems. First, the hybrid multiagent system is proposed, which is composed of continuous-time and discrete-time dynamic agents. Then, three kinds of consensus protocols are presented for the hybrid multiagent system. The analysis tool developed in this brief is based on the matrix theory and graph theory. With different restrictions of the sampling period, some necessary and sufficient conditions are established for solving the consensus of the hybrid multiagent system. The consensus states are also obtained under different protocols. Finally, simulation examples are provided to demonstrate the effectiveness of our theoretical results.

  9. Intuitionistic hybrid logic

    DEFF Research Database (Denmark)

    Braüner, Torben

    2011-01-01

    Intuitionistic hybrid logic is hybrid modal logic over an intuitionistic logic basis instead of a classical logical basis. In this short paper we introduce intuitionistic hybrid logic and we give a survey of work in the area.......Intuitionistic hybrid logic is hybrid modal logic over an intuitionistic logic basis instead of a classical logical basis. In this short paper we introduce intuitionistic hybrid logic and we give a survey of work in the area....

  10. Continuity Controlled Hybrid Automata

    OpenAIRE

    Bergstra, J. A.; Middelburg, C.A.

    2004-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of hybrid automata as timed transition systems. We also relate the synchronized product operator on hybrid automata to the parallel composition operator of the process algebra. It turns out that the f...

  11. Superposition Enhanced Nested Sampling

    Directory of Open Access Journals (Sweden)

    Stefano Martiniani

    2014-08-01

    Full Text Available The theoretical analysis of many problems in physics, astronomy, and applied mathematics requires an efficient numerical exploration of multimodal parameter spaces that exhibit broken ergodicity. Monte Carlo methods are widely used to deal with these classes of problems, but such simulations suffer from a ubiquitous sampling problem: The probability of sampling a particular state is proportional to its entropic weight. Devising an algorithm capable of sampling efficiently the full phase space is a long-standing problem. Here, we report a new hybrid method for the exploration of multimodal parameter spaces exhibiting broken ergodicity. Superposition enhanced nested sampling combines the strengths of global optimization with the unbiased or athermal sampling of nested sampling, greatly enhancing its efficiency with no additional parameters. We report extensive tests of this new approach for atomic clusters that are known to have energy landscapes for which conventional sampling schemes suffer from broken ergodicity. We also introduce a novel parallelization algorithm for nested sampling.

  12. Spatial planning

    OpenAIRE

    Dimitrov, Nikola; Koteski, Cane

    2016-01-01

    The professional book ,, Space planning "processed chapters on: space, concept and definition of space, space as a system, spatial economics, economic essence of space, space planning, social determinants of spatial planning, spatial planning as a process, factors development and elements in spatial planning, methodology, components and content of spatial planning stages and types of preparation of spatial planning, spatial planning and industrialization, industrialization, urbanization and s...

  13. Spatial planning

    OpenAIRE

    Dimitrov, Nikola; Koteski, Cane

    2016-01-01

    The professional book ,, Space planning "processed chapters on: space, concept and definition of space, space as a system, spatial economics, economic essence of space, space planning, social determinants of spatial planning, spatial planning as a process, factors development and elements in spatial planning, methodology, components and content of spatial planning stages and types of preparation of spatial planning, spatial planning and industrialization, industrialization, urbanization and s...

  14. Genetic Algorithm Based Robust and Optimal Path Planning for Sample-Return Mission from an Asteroid on an Earth Fly-By Trajectory

    CERN Document Server

    Fritz, Sean

    2015-01-01

    In this study, an interplanetary space flight mission design is established to obtain the minimum \\(\\Delta V\\) required for a rendezvous and sample return mission from an asteroid. Given the initial (observed) conditions of an asteroid, a (robust) genetic algorithm is implemented to determine the optimal choice of \\(\\Delta V\\) required for the rendezvous. Robustness of the optimum solution is demonstrated through incorporated bounded-uncertainties in the outbound \\(\\Delta V\\) maneuver via genetic fitness function. The improved algorithm results in a solution with improved robustness and reduced sensitivity to propulsive errors in the outbound maneuver. This is achieved over a solution optimized solely on \\(\\Delta V\\), while keeping the increase in \\(\\Delta V\\) to a minimum, as desired. Outcomes of the analysis provide significant results in terms of improved robustness in asteroid rendezvous missions.

  15. Estimating statistical uncertainty of Monte Carlo efficiency-gain in the context of a correlated sampling Monte Carlo code for brachytherapy treatment planning with non-normal dose distribution

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, Nitai D. [Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298 (United States); Sampson, Andrew J. [Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA 23298 (United States); Deniz, Daniel; Alm Carlsson, Gudrun [Department of Radiation Physics, Faculty of Health Sciences, Linkoeping University, SE 581 85 (Sweden); Williamson, Jeffrey [Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA 23298 (United States); Malusek, Alexandr, E-mail: malusek@ujf.cas.cz [Department of Radiation Physics, Faculty of Health Sciences, Linkoeping University, SE 581 85 (Sweden); Department of Radiation Dosimetry, Nuclear Physics Institute AS CR v.v.i., Na Truhlarce 39/64, 180 86 Prague (Czech Republic)

    2012-01-15

    Correlated sampling Monte Carlo methods can shorten computing times in brachytherapy treatment planning. Monte Carlo efficiency is typically estimated via efficiency gain, defined as the reduction in computing time by correlated sampling relative to conventional Monte Carlo methods when equal statistical uncertainties have been achieved. The determination of the efficiency gain uncertainty arising from random effects, however, is not a straightforward task specially when the error distribution is non-normal. The purpose of this study is to evaluate the applicability of the F distribution and standardized uncertainty propagation methods (widely used in metrology to estimate uncertainty of physical measurements) for predicting confidence intervals about efficiency gain estimates derived from single Monte Carlo runs using fixed-collision correlated sampling in a simplified brachytherapy geometry. A bootstrap based algorithm was used to simulate the probability distribution of the efficiency gain estimates and the shortest 95% confidence interval was estimated from this distribution. It was found that the corresponding relative uncertainty was as large as 37% for this particular problem. The uncertainty propagation framework predicted confidence intervals reasonably well; however its main disadvantage was that uncertainties of input quantities had to be calculated in a separate run via a Monte Carlo method. The F distribution noticeably underestimated the confidence interval. These discrepancies were influenced by several photons with large statistical weights which made extremely large contributions to the scored absorbed dose difference. The mechanism of acquiring high statistical weights in the fixed-collision correlated sampling method was explained and a mitigation strategy was proposed.

  16. Estimating statistical uncertainty of Monte Carlo efficiency-gain in the context of a correlated sampling Monte Carlo code for brachytherapy treatment planning with non-normal dose distribution.

    Science.gov (United States)

    Mukhopadhyay, Nitai D; Sampson, Andrew J; Deniz, Daniel; Alm Carlsson, Gudrun; Williamson, Jeffrey; Malusek, Alexandr

    2012-01-01

    Correlated sampling Monte Carlo methods can shorten computing times in brachytherapy treatment planning. Monte Carlo efficiency is typically estimated via efficiency gain, defined as the reduction in computing time by correlated sampling relative to conventional Monte Carlo methods when equal statistical uncertainties have been achieved. The determination of the efficiency gain uncertainty arising from random effects, however, is not a straightforward task specially when the error distribution is non-normal. The purpose of this study is to evaluate the applicability of the F distribution and standardized uncertainty propagation methods (widely used in metrology to estimate uncertainty of physical measurements) for predicting confidence intervals about efficiency gain estimates derived from single Monte Carlo runs using fixed-collision correlated sampling in a simplified brachytherapy geometry. A bootstrap based algorithm was used to simulate the probability distribution of the efficiency gain estimates and the shortest 95% confidence interval was estimated from this distribution. It was found that the corresponding relative uncertainty was as large as 37% for this particular problem. The uncertainty propagation framework predicted confidence intervals reasonably well; however its main disadvantage was that uncertainties of input quantities had to be calculated in a separate run via a Monte Carlo method. The F distribution noticeably underestimated the confidence interval. These discrepancies were influenced by several photons with large statistical weights which made extremely large contributions to the scored absorbed dose difference. The mechanism of acquiring high statistical weights in the fixed-collision correlated sampling method was explained and a mitigation strategy was proposed.

  17. Hybridized tetraquarks

    Directory of Open Access Journals (Sweden)

    A. Esposito

    2016-07-01

    Full Text Available We propose a new interpretation of the neutral and charged X,Z exotic hadron resonances. Hybridized-tetraquarks are neither purely compact tetraquark states nor bound or loosely bound molecules but rather a manifestation of the interplay between the two. While meson molecules need a negative or zero binding energy, its counterpart for h-tetraquarks is required to be positive. The formation mechanism of this new class of hadrons is inspired by that of Feshbach metastable states in atomic physics. The recent claim of an exotic resonance in the Bs0π± channel by the D0 Collaboration and the negative result presented subsequently by the LHCb Collaboration are understood in this scheme, together with a considerable portion of available data on X,Z particles. Considerations on a state with the same quantum numbers as the X(5568 are also made.

  18. Hybridized Tetraquarks

    CERN Document Server

    Esposito, A.; Polosa, A.D.

    2016-01-01

    We propose a new interpretation of the neutral and charged X, Z exotic hadron resonances. Hybridized-tetraquarks are neither purely compact tetraquark states nor bound or loosely bound molecules. The latter would require a negative or zero binding energy whose counterpart in h-tetraquarks is a positive quantity. The formation mechanism of this new class of hadrons is inspired by that of Feshbach metastable states in atomic physics. The recent claim of an exotic resonance in the Bs pi+- channel by the D0 collaboration and the negative result presented subsequently by the LHCb collaboration are understood in this scheme, together with a considerable portion of available data on X, Z particles. Considerations on a state with the same quantum numbers as the X(5568) are also made.

  19. Evolved Gas Measurements Planned for the Lower Layers of the Gale Crater Mound with the Sample Analysis at Mars Instrument Suite

    Science.gov (United States)

    Mahaffy, Paul; Brunner, Anna; McAdam, Amy; Franz, Heather; Conrad, Pamela; Webster, Chris; Cabane, Michel

    2009-01-01

    The lower mound strata of Gale Crater provide a diverse set of chemical environments for exploration by the varied tools of the Curiosity Rover of the Mars Science Laboratory (MSL) Mission. Orbital imaging and spectroscopy clearly reveal distinct layers of hydrated minerals, sulfates, and clays with abundant evidence of a variety of fluvial processes. The three instruments of the MSL Sample Analysis at aMars (SAM) investigation, the Quadrupole Mass Spectrometer (QMS), the Tunable Laser Spectrometer (TLS), and the Gas Chromatograph (GC) are designed to analyze either atmospheric gases or volatiles thermally evolved or chemically extracted from powdered rock or soil. The presence or absence of organic compounds in these layers is of great interest since such an in situ search for this type of record has not been successfully implemented since the mid-60s Viking GCMS experiments. However, regardless of the outcome of the analysis for organics, the abundance and isotopic composition of thermally evolved inorganic compounds should also provide a rich data set to complement the mineralogical and elemental information provided by other MSL instruments. In addition, these evolved gas analysis (EGA) experiments will help test sedimentary models proposed by Malin and Edgett (2000) and then further developed by Milliken et al (2010) for Gale Crater. In the SAM EGA experiments the evolution temperatures of H2O, CO2, SO2, O2, or other simple compounds as the samples are heated in a helium stream to 1000 C provides information on mineral types and their associations. The isotopic composition of O, H, C, and S can be precisely determined in several evolved compounds and compared with the present day atmosphere. Such SAM results might be able to test mineralogical evidence of changing sedimentary and alteration processes over an extended period of time. For example, Bibring et al (2006) have suggested such a major shift from early nonacidic to later acidic alteration. We will

  20. A Future with Hybrid Electric Propulsion Systems: A NASA Perspective

    Science.gov (United States)

    DelRosario, Ruben

    2014-01-01

    The presentation highlights a NASA perspective on Hybrid Electric Propulsion Systems for aeronautical applications. Discussed are results from NASA Advance Concepts Study for Aircraft Entering service in 2030 and beyond and the potential use of hybrid electric propulsion systems as a potential solution to the requirements for energy efficiency and environmental compatibility. Current progress and notional potential NASA research plans are presented.

  1. Continuity Controlled Hybrid Automata

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2004-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of

  2. Continuity controlled Hybrid Automata

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2008-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of

  3. Testing Theory of Planned Behavior and Neo-Socioanalytic Theory models of trait activity, industriousness, exercise social cognitions, exercise intentions, and physical activity in a representative U.S. sample

    Science.gov (United States)

    Vo, Phuong T.; Bogg, Tim

    2015-01-01

    Prior research identified assorted relations between trait and social cognition models of personality and engagement in physical activity. Using a representative U.S. sample (N = 957), the goal of the present study was to test two alternative structural models of the relationships among the extraversion-related facet of activity, the conscientiousness-related facet of industriousness, social cognitions from the Theory of Planned Behavior (perceived behavioral control, affective attitudes, subjective norms, intentions), Social Cognitive Theory (self-efficacy, outcome expectancies), and the Transtheoretical Model (behavioral processes of change), and engagement in physical activity. Path analyses with bootstrapping procedures were used to model direct and indirect effects of trait and social cognition constructs on physical activity through two distinct frameworks – the Theory of Planned Behavior and Neo-Socioanalytic Theory. While both models showed good internal fit, comparative model information criteria showed the Theory-of-Planned-Behavior-informed model provided a better fit. In the model, social cognitions fully mediated the relationships from the activity facet and industriousness to intentions for and engagement in physical activity, such that the relationships were primarily maintained by positive affective evaluations, positive expected outcomes, and confidence in overcoming barriers related to physical activity engagement. The resultant model – termed the Disposition-Belief-Motivation model– is proposed as a useful framework for organizing and integrating personality trait facets and social cognitions from various theoretical perspectives to investigate the expression of health-related behaviors, such as physical activity. Moreover, the results are discussed in terms of extending the application of the Disposition-Belief-Motivation model to longitudinal and intervention designs for physical activity engagement. PMID:26300811

  4. Testing Theory of Planned Behavior and Neo-Socioanalytic Theory models of trait activity, industriousness, exercise social cognitions, exercise intentions, and physical activity in a representative U.S. sample.

    Science.gov (United States)

    Vo, Phuong T; Bogg, Tim

    2015-01-01

    Prior research identified assorted relations between trait and social cognition models of personality and engagement in physical activity. Using a representative U.S. sample (N = 957), the goal of the present study was to test two alternative structural models of the relationships among the extraversion-related facet of activity, the conscientiousness-related facet of industriousness, social cognitions from the Theory of Planned Behavior (perceived behavioral control, affective attitudes, subjective norms, intentions), Social Cognitive Theory (self-efficacy, outcome expectancies), and the Transtheoretical Model (behavioral processes of change), and engagement in physical activity. Path analyses with bootstrapping procedures were used to model direct and indirect effects of trait and social cognition constructs on physical activity through two distinct frameworks - the Theory of Planned Behavior and Neo-Socioanalytic Theory. While both models showed good internal fit, comparative model information criteria showed the Theory-of-Planned-Behavior-informed model provided a better fit. In the model, social cognitions fully mediated the relationships from the activity facet and industriousness to intentions for and engagement in physical activity, such that the relationships were primarily maintained by positive affective evaluations, positive expected outcomes, and confidence in overcoming barriers related to physical activity engagement. The resultant model - termed the Disposition-Belief-Motivation model- is proposed as a useful framework for organizing and integrating personality trait facets and social cognitions from various theoretical perspectives to investigate the expression of health-related behaviors, such as physical activity. Moreover, the results are discussed in terms of extending the application of the Disposition-Belief-Motivation model to longitudinal and intervention designs for physical activity engagement.

  5. Testing Theory of Planned Behavior and Neo-Socioanalytic Theory models of trait activity, industriousness, exercise social cognitions, exercise intentions, and physical activity in a representative U.S. sample

    Directory of Open Access Journals (Sweden)

    Phuong Thi Vo

    2015-08-01

    Full Text Available Prior research identified assorted relations between trait and social cognition models of personality and engagement in physical activity. Using a representative U.S. sample (N = 957, the goal of the present study was to test two alternative structural models of the relationships among the extraversion-related facet of activity, the conscientiousness-related facet of industriousness, social cognitions from the Theory of Planned Behavior (perceived behavioral control, affective attitudes, subjective norms, intentions, Social Cognitive Theory (self-efficacy, outcome expectancies, and the Transtheoretical Model (behavioral processes of change, and engagement in physical activity. Path analyses with bootstrapping procedures were used to model direct and indirect effects of trait and social cognition constructs on physical activity through two distinct frameworks – the Theory of Planned Behavior and Neo-Socioanalytic Theory. While both models showed good internal fit, comparative model information criteria showed the Theory-of-Planned-Behavior-informed model provided a better fit. In the model, social cognitions fully mediated the relationships from the activity facet and industriousness to intentions for and engagement in physical activity, such that the relationships were primarily maintained by positive affective evaluations, positive expected outcomes, and confidence in overcoming barriers related to physical activity engagement. The resultant model – termed the Disposition-Belief-Motivation model – is proposed as a useful framework for organizing and integrating personality trait facets and social cognitions from various theoretical perspectives to investigate the expression of health-related behaviors, such as physical activity. Moreover, the results are discussed in terms of extending the application of the Disposition-Belief-Motivation model to longitudinal and intervention designs for physical activity engagement.

  6. Analysis of industry-generated data. Part 1: a baseline for the development of a tool to assist the milk industry in designing sampling plans for controlling aflatoxin M1 in milk.

    Science.gov (United States)

    Trevisani, Marcello; Farkas, Zsuzsa; Serraino, Andrea; Zambrini, Angelo Vittorio; Pizzamiglio, Valentina; Giacometti, Federica; Ámbrus, Arpád

    2014-01-01

    The presence of aflatoxin M1 (AFM1) in milk was assessed in Italy in the framework of designing a monitoring plan actuated by the milk industry in the period 2005-10. Overall, 21,969 samples were taken from tankers collecting milk from 690 dairy farms. The milk samples were representative of the consignments of co-mingled milk received from multiple (two to six) farms. Systematic, biweekly sampling of consignments involved each of the 121 districts (70 in the North, 17 in the Central and 34 in the South regions of Italy). AFM1 concentration was measured using an enzyme-linked immunoassay method (validated within the range of 5-100 ng kg(-1)) whereas an HPLC method was used for the quantification of levels in the samples that had concentrations higher than 100 ng kg(-1). Process control charts using data collected in three processing plants illustrate, as an example, the seasonal variation of the contamination. The mean concentration of AFM1 was in the range between 11 and 19 ng kg(-1). The 90th and 99th percentile values were 19-34 and 41-91 ng kg(-1), respectively, and values as high as 280 ng kg(-1) were reached in 2008. The number of non-compliant consignments (those with an AFM1 concentration above the statutory limit of 50 ng kg(-1)) varied between 0.3% and 3.1% per year, with peaks in September, after the maize harvest season. The variability between different regions was not significant. The results show that controlling the aflatoxins in feed at farm level was inadequate, consequently screening of raw milk prior to processing was needed. The evaluation of the AFM1 contamination level observed during a long-term period can provide useful data for defining the frequency of sampling.

  7. Planning Lessons

    Institute of Scientific and Technical Information of China (English)

    Linda Jensen

    2007-01-01

    @@ Jensen's "Lesson Planning"article serves aS a guide fOr novice teachers who need to create formalized lesson plans.The article covers why,when,and how teachers plan lessons,as well aS basic lesson plan principles and a lesson plan template.

  8. Language Planning: Corpus Planning.

    Science.gov (United States)

    Baldauf, Richard B., Jr.

    1989-01-01

    Focuses on the historical and sociolinguistic studies that illuminate corpus planning processes. These processes are broken down and discussed under two categories: those related to the establishment of norms, referred to as codification, and those related to the extension of the linguistic functions of language, referred to as elaboration. (60…

  9. Focused Feasibility Study Final Field Sampling Plan

    Science.gov (United States)

    1993-10-01

    Military Police (410) 671-2222/2628 Commissioned Officer Operations Francine Gordon JEG Project Manager (202) 789-7290 Wayne Mandell JEG Task Manager...1986 - March 1988. U.S. Geological Survey Open File Report 89-387, Towson , MD Oliveros, James P. and Don A, Vroblesky, 1989, Hydrology of the Canal

  10. Markovian Time-Delay Sampling Policies.

    Science.gov (United States)

    1980-08-01

    Markovian sampling policy for water quality monitoring. Biometrics 33: 41-46. Wald , A. and Wolfowitz , J. (1945). Sampling inspection plans for...to remain in control. This idea is not new. Sampling plans for the percent defective were devised along these lines by Dodge (1943), Wald and... Wolfowitz (1945), and Dodge and Torrey (1951), who gave rules for switching from 100% sampling to sampling a fraction f. Multi-level inspec- tion plans having

  11. Hybridization and Selective Release of DNA Microarrays

    Energy Technology Data Exchange (ETDEWEB)

    Beer, N R; Baker, B; Piggott, T; Maberry, S; Hara, C M; DeOtte, J; Benett, W; Mukerjee, E; Dzenitis, J; Wheeler, E K

    2011-11-29

    DNA microarrays contain sequence specific probes arrayed in distinct spots numbering from 10,000 to over 1,000,000, depending on the platform. This tremendous degree of multiplexing gives microarrays great potential for environmental background sampling, broad-spectrum clinical monitoring, and continuous biological threat detection. In practice, their use in these applications is not common due to limited information content, long processing times, and high cost. The work focused on characterizing the phenomena of microarray hybridization and selective release that will allow these limitations to be addressed. This will revolutionize the ways that microarrays can be used for LLNL's Global Security missions. The goals of this project were two-fold: automated faster hybridizations and selective release of hybridized features. The first study area involves hybridization kinetics and mass-transfer effects. the standard hybridization protocol uses an overnight incubation to achieve the best possible signal for any sample type, as well as for convenience in manual processing. There is potential to significantly shorten this time based on better understanding and control of the rate-limiting processes and knowledge of the progress of the hybridization. In the hybridization work, a custom microarray flow cell was used to manipulate the chemical and thermal environment of the array and autonomously image the changes over time during hybridization. The second study area is selective release. Microarrays easily generate hybridization patterns and signatures, but there is still an unmet need for methodologies enabling rapid and selective analysis of these patterns and signatures. Detailed analysis of individual spots by subsequent sequencing could potentially yield significant information for rapidly mutating and emerging (or deliberately engineered) pathogens. In the selective release work, optical energy deposition with coherent light quickly provides the thermal energy

  12. Hybrid optofluidic biosensors

    Science.gov (United States)

    Parks, Joshua W.

    Optofluidics, born of the desire to create a system containing microfluidic environments with integrated optical elements, has seen dramatic increases in popularity over the last 10 years. In particular, the application of this technology towards chip based molecular sensors has undergone significant development. The most sensitive of these biosensors interface liquid- and solid-core antiresonant reflecting optical waveguides (ARROWs). These sensor chips are created using conventional silicon microfabrication. As such, ARROW technology has previously been unable to utilize state-of-the-art microfluidic developments because the technology used--soft polydimethyl siloxane (PDMS) micromolded chips--is unamenable to the silicon microfabrication workflows implemented in the creation of ARROW detection chips. The original goal of this thesis was to employ hybrid integration, or the connection of independently designed and fabricated optofluidic and microfluidic chips, to create enhanced biosensors with the capability of processing and detecting biological samples on a single hybrid system. After successful demonstration of this paradigm, this work expanded into a new direction--direct integration of sensing and detection technologies on a new platform with dynamic, multi-dimensional photonic re-configurability. This thesis reports a number of firsts, including: • 1,000 fold optical transmission enhancement of ARROW optofluidic detection chips through thermal annealing, • Detection of single nucleic acids on a silicon-based ARROW chip, • Hybrid optofluidic integration of ARROW detection chips and passive PDMS microfluidic chips, • Hybrid optofluidic integration of ARROW detection chips and actively controllable PDMS microfluidic chips with integrated microvalves, • On-chip concentration and detection of clinical Ebola nucleic acids, • Multimode interference (MMI) waveguide based wavelength division multiplexing for detection of single influenza virions,

  13. Rulison Monitoring Plan

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-07-01

    The Project Rulison Monitoring Plan has been developed as part of the U.S. Department of Energy (DOE) Office of Legacy Management's mission to protect human health and the environment. The purpose of the plan is to monitor fluids from gas wells for radionuclides that would indicate contamination is migrating from the Rulison detonation zone to producing gas wells, allowing action to be taken before the contamination could pose a risk. The Monitoring Plan (1) lists the contaminants present and identifies those that have the greatest potential to migrate from the detonation zone (radionuclide source term), (2) identifies locations that monitor the most likely transport pathways, (3) identifies which fluids will be sampled (gas and liquid) and why, (4) establishes the frequency of sampling, and (5) specifies the most practical analyses and where the analysis results will be reported. The plan does not affect the long-term hydrologic sampling conducted by DOE since 1972, which will continue for the purpose of sampling shallow groundwater and surface water near the site. The Monitoring Plan was developed in anticipation of gas wells being drilled progressively nearer the Rulison site. DOE sampled 10 gas wells in 1997 and 2005 at distances ranging from 2.7 to 7.6 miles from the site to establish background concentrations for radionuclides. In a separate effort, gas industry operators and the Colorado Oil and Gas Conservation Commission (COGCC) developed an industry sampling and analysis plan that was implemented in 2007. The industry plan requires the sampling of gas wells within 3 miles of the site, with increased requirements for wells within 1 mile of the site. The DOE plan emphasizes the sampling of wells near the site (Figure 1), specifically those with a bottom-hole location of 1 mile or less from the detonation, depending on the direction relative to the natural fracture trend of the producing formation. Studies indicate that even the most mobile

  14. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    Energy Technology Data Exchange (ETDEWEB)

    Nickels, J.M.

    1991-06-01

    This Quality Assurance Project Plan addresses the quality assurance requirements for the Facility Monitoring Plans of the overall site-wide environmental monitoring plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of individual Facility Effluent Monitoring Plans. This document is intended to be a basic road map to the Facility Effluent Monitoring Plan documents (i.e., the guidance document for preparing Facility Effluent Monitoring Plans, Facility Effluent Monitoring Plan determinations, management plan, and Facility Effluent Monitoring Plans). The implementing procedures, plans, and instructions are appropriate for the control of effluent monitoring plans requiring compliance with US Department of Energy, US Environmental Protection Agency, state, and local requirements. This Quality Assurance Project Plan contains a matrix of organizational responsibilities, procedural resources from facility or site manuals used in the Facility Effluent Monitoring Plans, and a list of the analytes of interest and analytical methods for each facility preparing a Facility Effluent Monitoring Plan. 44 refs., 1 figs., 2 tabs.

  15. Lesson Planning the Kodaly Way.

    Science.gov (United States)

    Boshkoff, Ruth

    1991-01-01

    Discusses the contribution of Zoltan Kodaly to music lesson planning. Emphasizes preparation, presentation, and practice as the three important strategies in teaching concepts and skills to be included in a lesson plan. Includes a sample lesson plan covering a semester and advice on choosing song material. (DK)

  16. Next-generation hybridization and introgression

    Science.gov (United States)

    Twyford, A D; Ennos, R A

    2012-01-01

    Hybridization has a major role in evolution—from the introgression of important phenotypic traits between species, to the creation of new species through hybrid speciation. Molecular studies of hybridization aim to understand the class of hybrids and the frequency of introgression, detect the signature of ancient hybridization, and understand the behaviour of introgressed loci in their new genomic background. This often involves a large investment in the design and application of molecular markers, leading to a compromise between the depth and breadth of genomic data. New techniques designed to assay a large sub-section of the genome, in association with next-generation sequencing (NGS) technologies, will allow genome-wide hybridization and introgression studies in organisms with no prior sequence data. These detailed genotypic data will unite the breadth of sampling of loci characteristic of population genetics with the depth of sequence information associated with molecular phylogenetics. In this review, we assess the theoretical and methodological constraints that limit our understanding of natural hybridization, and promote the use of NGS for detecting hybridization and introgression between non-model organisms. We also make recommendations for the ways in which emerging techniques, such as pooled barcoded amplicon sequencing and restriction site-associated DNA tags, should be used to overcome current limitations, and enhance our understanding of this evolutionary significant process. PMID:21897439

  17. From hybrid swarms to swarms of hybrids