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Sample records for hybrid iii head

  1. A Modified Hybrid III 6-Year-Old Dummy Head Model for Lateral Impact Assessment

    Directory of Open Access Journals (Sweden)

    I. A. Rafukka

    2016-01-01

    Full Text Available Hybrid III six-year-old (6YO child dummy head model was developed and validated for frontal impact assessment according to the specifications contained in Code of Federal Regulations, Title 49, Part 572.122, Subpart N by Livermore Software Technology Corporation (LSTC. This work is aimed at improving biofidelity of the head for frontal impact and also extending its application to lateral impact assessment by modifying the head skin viscoelastic properties and validating the head response using the scaled nine-year-old (9YO child cadaver head response recently published in the literature. The modified head model was validated for two drop heights for frontal, right, and left parietal impact locations. Peak resultant acceleration of the modified head model appeared to have good correlation with scaled 9YO child cadaver head response for frontal impact on dropping from 302 mm height and fair correlation with 12.3% difference for 151 mm drop height. Right parietal peak resultant acceleration values correlate well with scaled 9YO head experimental data for 153 mm drop height, while fair correlation with 16.4% difference was noticed for 302 mm drop height. Left parietal, however, shows low biofidelity for the two drop heights as the difference in head acceleration response was within 30%. The modified head model could therefore be used to estimate injuries in vehicle crash for head parietal impact locations which cannot be measured by the current hybrid III dummy head model.

  2. Head excursion of restrained human volunteers and hybrid III dummies in steady state rollover tests.

    Science.gov (United States)

    Moffatt, Edward; Hare, Barry; Hughes, Raymond; Lewis, Lance; Iiyama, Hiroshi; Curzon, Anne; Cooper, Eddie

    2003-01-01

    Seatbelts provide substantial benefits in rollover crashes, yet occupants still receive head and neck injuries from contacting the vehicle roof interior when the roof exterior strikes the ground. Prior research has evaluated rollover restraint performance utilizing anthropomorphic test devices (dummies), but little dynamic testing has been done with human volunteers to learn how they move during rollovers. In this study, the vertical excursion of the head of restrained dummies and human subjects was measured in a vehicle being rotated about its longitudinal roll axis at roll rates from 180-to-360 deg/sec and under static inversion conditions. The vehicle's restraint design was the commonly used 3-point seatbelt with continuous loop webbing and a sliding latch plate. This paper presents an analysis of the observed occupant motion and provides a comparison of dummy and human motion under similar test conditions. Thirty-five tests (eighteen static and seventeen dynamic) were completed using two different sizes of dummies and human subjects in both near and far-side roll directions. The research indicates that far-side rollovers cause the restrained test subjects to have greater head excursion than near-side rollovers, and that static inversion testing underestimates head excursion for far-side occupants. Human vertical head excursion of up to 200 mm was found at a roll rate of 220 deg/sec. Humans exhibit greater variability in head excursion in comparison to dummies. Transfer of seatbelt webbing through the latch plate did not correlate directly with differences in head excursion.

  3. Measurement of Hybrid III Head Impact Kinematics Using an Accelerometer and Gyroscope System in Ice Hockey Helmets.

    Science.gov (United States)

    Allison, Mari A; Kang, Yun Seok; Maltese, Matthew R; Bolte, John H; Arbogast, Kristy B

    2015-08-01

    Helmet-based instrumentation is used to study the biomechanics of concussion. The most extensively used systems estimate rotational acceleration from linear acceleration, but new instrumentation measures rotational velocity using gyroscopes, potentially reducing error. This study compared kinematics from an accelerometer and gyroscope-containing system to reference measures. A Hybrid III (HIII) adult male anthropometric test device head and neck was fit with two helmet brands, each instrumented with gForce Tracker (GFT) sensor systems in four locations. Helmets were impacted at various speeds and directions. Regression relationships between GFT-measured and reference peak kinematics were quantified, and influence of impact direction, sensor location, and helmet brand was evaluated. The relationship between the sensor output and the reference acceleration/velocity experienced by the head was strong. Coefficients of determination for data stratified by individual impact directions ranged from 0.77 to 0.99 for peak linear acceleration and from 0.78 to 1.0 for peak rotational velocity. For the data from all impact directions combined, coefficients of determination ranged from 0.60 to 0.80 for peak resultant linear acceleration and 0.83 to 0.91 for peak resultant rotational velocity. As expected, raw peak resultant linear acceleration measures exhibited large percent differences from reference measures. Adjustment using regressions resulted in average absolute errors of 10-15% if regression adjustments were done by impact direction or 25-40% if regressions incorporating data from all impact directions were used. Average absolute percent differences in raw peak resultant rotational velocity were much lower, around 10-15%. It is important to define system accuracy for a particular helmet brand, sensor location, and impact direction in order to interpret real-world data.

  4. Rear impact responses of different sized adult Hybrid III dummies.

    Science.gov (United States)

    DeRosia, John; Yoganandan, Narayan; Pintar, Frank A

    2004-03-01

    Rear impact sled tests were conducted using 5th, 50th, and 95th percentile Hybrid III dummies to evaluate proposed injury criteria. Different head restraint height (750, 800 mm) and backset (0, 50, 100 mm) positions were used to determine axial and shear forces, bending moments, and injury criteria (NIC, N(ij), and N(km)). The time sequence to attain each parameter was also determined. Three events were identified in the response. Event I was coincident with the maximum rearward motion of the torso, Event II occurred at the time of the peak upper neck flexion moment, and Event III occurred at the time of maximum rearward motion of the head. Parameters such as backset, head restraint height, seat-head restraint interaction, and anthropometry affected impact responses. Head rotations increased with increasing backset and increasing head restraint height. However, N(ij) and N(km) did not exhibit such clear trends. The 50th percentile dummy responded with consistent injury criteria values (e.g., the magnitude of the injury criteria increased with backset increase or head restraint height decrease). However, the 5th and 95th percentile dummies did not demonstrate such trends. These findings underscore the need to include subject anthropometry in addition to seat and head restraint characteristics for better assessment of rear impact responses.

  5. Hybrid III-V/silicon lasers

    Science.gov (United States)

    Kaspar, P.; Jany, C.; Le Liepvre, A.; Accard, A.; Lamponi, M.; Make, D.; Levaufre, G.; Girard, N.; Lelarge, F.; Shen, A.; Charbonnier, P.; Mallecot, F.; Duan, G.-H.; Gentner, J.-.; Fedeli, J.-M.; Olivier, S.; Descos, A.; Ben Bakir, B.; Messaoudene, S.; Bordel, D.; Malhouitre, S.; Kopp, C.; Menezo, S.

    2014-05-01

    The lack of potent integrated light emitters is one of the bottlenecks that have so far hindered the silicon photonics platform from revolutionizing the communication market. Photonic circuits with integrated light sources have the potential to address a wide range of applications from short-distance data communication to long-haul optical transmission. Notably, the integration of lasers would allow saving large assembly costs and reduce the footprint of optoelectronic products by combining photonic and microelectronic functionalities on a single chip. Since silicon and germanium-based sources are still in their infancy, hybrid approaches using III-V semiconductor materials are currently pursued by several research laboratories in academia as well as in industry. In this paper we review recent developments of hybrid III-V/silicon lasers and discuss the advantages and drawbacks of several integration schemes. The integration approach followed in our laboratory makes use of wafer-bonded III-V material on structured silicon-on-insulator substrates and is based on adiabatic mode transfers between silicon and III-V waveguides. We will highlight some of the most interesting results from devices such as wavelength-tunable lasers and AWG lasers. The good performance demonstrates that an efficient mode transfer can be achieved between III-V and silicon waveguides and encourages further research efforts in this direction.

  6. Comparison of Hybrid III and THOR dummies in paired small overlap tests.

    Science.gov (United States)

    Mueller, Becky C; Sherwood, Christopher P; Arbelaez, Raul A; Zuby, David S; Nolan, Joseph M

    2011-11-01

    The Insurance Institute for Highway Safety (IIHS) is investigating small overlap crash test procedures for a possible consumer information program. Analysis of real-world small overlap crashes found a strong relationship between serious head and chest injuries and occupant compartment intrusion. The main sources of serious head injuries were from the A-pillar, dash panel, or door structure, suggesting head trajectories forward and outboard possibly bypassing the airbag. Chest injuries mainly were from steering wheel intrusion and seat belt loading. In developing this program, two test dummies were evaluated for predicting occupant injury risk: midsize male Hybrid III and THOR. In the collinear small overlap crash tests conducted here, results from the two dummies were similar. Both predicted a low risk of injury to the head and chest and sometimes a high risk of injury to the lower extremities. Head and torso kinematics also were similar between dummies. Other test scenarios might show larger differences between the dummies.

  7. Dissection of Genetic Mechanism of Abnormal Heading in Hybrid Rice

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hong-jun; QU Li-jun; XIANG Chao; WANG Hui; XIA Jia-fa; LI Ze-fu; GAO Yong-ming; SHI Ying-yao

    2014-01-01

    Abnormal heading in hybrid rice production has caused great economic loss in recent years, but the genetic basis of this phenomenon remains elusive. In this study, we developed four testcross populations using 38 introgression lines (ILs) from Shuhui 527 (SH527)/Fuhui 838 (FH838)//SH527 population as male parents and four male sterile lines (MSLs; namely II-32A, Xieqingzao A, Gang 46A and Jin 23A) as female parents. Progeny testing allowed us to identify 55 abnormal heading combinations in Hefei, but had late heading date in Hangzhou and Guangzhou of China. By one-and two-way analysis of variance, a total of 21 QTLs and 31 pairs of epistatic QTLs associated with photosensitivity were identified in the four populations, respectively. Genotypic analysis showed that the IL parent of most abnormal heading combinations showed some introgressions at markers RM331 and RM3395 on chromosome 8 (strongly associated with the known genes OsHAP3H/DTH8/Ghd8/LHD1) of donor FH838 alleles, and these two markers were also identified as affecting photosensitivity. The observation that the recipient parent (SH527), donor parent (FH838), their testcross combinations with four MSLs, and the IL parents of abnormal heading combinations had normal heading date in Hefei suggested that OsHAP3H/DTH8/Ghd8/LHD1 showed no independent regulation on abnormal heading in the abnormal heading combinations. It is noteworthy that complex epistasis among RM331 or RM3395 with other loci, including dominant × additive, additive × dominant, and dominant × dominant epistases, were identified only in the four testcross populations of the current study, but not in the SH527/FH838//SH527 population, suggesting the cause of abnormal heading in abnormal heading combinations in Hefei and delayed heading in Hangzhou and Guangzhou.

  8. The evaluation of MiL-Lx and Hybrid III Leg using Hybrid III and EUROSID2-re Anthropomorphic Test Devices

    CSIR Research Space (South Africa)

    Pandelani, T

    2012-09-01

    Full Text Available the standard in automotive testing until the Hybrid III family of ATDs was introduced in 1987. The Hybrid III addressed deficiencies of the Hybrid II, mainly in the area of the neck performance and provided improved bio-fidelity. The Hybrid III ATD also... used a curved spine which better represented the occupant in a sitting position, as opposed to the original Hybrid II straight spine. The Hybrid III is still the standard in automotive crash testing; however, newer specialized ATDs...

  9. Hybrid III-V/SOI Resonant Cavity Photodetector

    DEFF Research Database (Denmark)

    Learkthanakhachon, Supannee; Taghizadeh, Alireza; Park, Gyeong Cheol;

    2016-01-01

    A hybrid III-V/SOI resonant cavity photo detector has been demonstrated, which comprises an InP grating reflectorand a Si grating reflector. It can selectively detects an incident light with 1.54-µm wavelength and TM polarization....

  10. Hybrid III-V Silicon Lasers

    Science.gov (United States)

    Bowers, John

    2014-03-01

    Abstract: A number of important breakthroughs in the past decade have focused attention on Si as a photonic platform. We review here recent progress in this field, focusing on efforts to make lasers, amplifiers, modulators and photodetectors on or in silicon. We also describe optimum quantum well design and distributed feedback cavity design to reduce the threshold and increase the efficiency and power output. The impact active silicon photonic integrated circuits could have on interconnects, telecommunications and on silicon electronics is reviewed. Biography: John Bowers holds the Fred Kavli Chair in Nanotechnology, and is the Director of the Institute for Energy Efficiency and a Professor in the Departments of Electrical and Computer Engineering and Materials at UCSB. He is a cofounder of Aurrion, Aerius Photonics and Calient Networks. Dr. Bowers received his M.S. and Ph.D. degrees from Stanford University and worked for AT&T Bell Laboratories and Honeywell before joining UC Santa Barbara. Dr. Bowers is a member of the National Academy of Engineering and a fellow of the IEEE, OSA and the American Physical Society. He is a recipient of the OSA/IEEE Tyndall Award, the OSA Holonyak Prize, the IEEE LEOS William Streifer Award and the South Coast Business and Technology Entrepreneur of the Year Award. He and coworkers received the EE Times Annual Creativity in Electronics (ACE) Award for Most Promising Technology for the hybrid silicon laser in 2007. Bowers' research is primarily in optoelectronics and photonic integrated circuits. He has published ten book chapters, 600 journal papers, 900 conference papers and has received 54 patents. He has published 180 invited papers and conference papers, and given 16 plenary talks at conferences. As well as Chong Zhang.

  11. Double Sided Si(Ge)/Sapphire/III-Nitride Hybrid Structure

    Science.gov (United States)

    Park, Yeonjoon (Inventor); Choi, Sang Hyouk (Inventor)

    2016-01-01

    One aspect of the present invention is a double sided hybrid crystal structure including a trigonal Sapphire wafer containing a (0001) C-plane and having front and rear sides. The Sapphire wafer is substantially transparent to light in the visible and infrared spectra, and also provides insulation with respect to electromagnetic radio frequency noise. A layer of crystalline Si material having a cubic diamond structure aligned with the cubic direction on the (0001) C-plane and strained as rhombohedron to thereby enable continuous integration of a selected (SiGe) device onto the rear side of the Sapphire wafer. The double sided hybrid crystal structure further includes an integrated III-Nitride crystalline layer on the front side of the Sapphire wafer that enables continuous integration of a selected III-Nitride device on the front side of the Sapphire wafer.

  12. Organic / IV, III-V Semiconductor Hybrid Solar Cells

    Directory of Open Access Journals (Sweden)

    Pang-Leen Ong

    2010-03-01

    Full Text Available We present a review of the emerging class of hybrid solar cells based on organic-semiconductor (Group IV, III-V, nanocomposites, which states separately from dye synthesized, polymer-metal oxides and organic-inorganic (Group II-VI nanocomposite photovoltaics. The structure of such hybrid cell comprises of an organic active material (p-type deposited by coating, printing or spraying technique on the surface of bulk or nanostructured semiconductor (n-type forming a heterojunction between the two materials. Organic components include various photosensitive monomers (e.g., phtalocyanines or porphyrines, conjugated polymers, and carbon nanotubes. Mechanisms of the charge separation at the interface and their transport are discussed. Also, perspectives on the future development of such hybrid cells and comparative analysis with other classes of photovoltaics of third generation are presented.

  13. An assessment of the response of Military lower extremity and Hybrid III leg during typical blast impact using the Hybrid III and EUROSID-2 ATD.

    CSIR Research Space (South Africa)

    Pandelani, T

    2014-09-01

    Full Text Available An assessment of the response of Military lower extremity and Hybrid III leg during typical blast impact using the Hybrid III and EUROSID-2 ATD Thanyani Pandelani, David Reinecke, Tleyane Sono, Frans Beetge and Phumlane Nkosi Abstract: This paper...

  14. Comparative Evaluation of the Q3 and Hybrid III 3-Year-Old Dummies in Biofidelity and Static Out-of-Position Airbag Tests.

    Science.gov (United States)

    Berliner, J; Athey, J; Baayoun, E; Byrnes, K; Elhagediab, A; Hultman, R; Jensen, J; Kim, A; Kostyniuk, G; Mertz, H; Prest, J; Rouhana, S; Scherer, R; Xu, L

    2000-11-01

    A comparison of the Q3 and Hybrid III 3-year-old crash test dummies is presented in this paper. The performance of the dummies were compared in sixty biofidelity tests, seventy-seven static out-of-position airbag tests and sixty-three calibration tests. Various time histories and other data pertaining to accelerations, deflections, forces and moments are compared. In addition, the ease of positioning, handling, and the durability of the dummies in various out-of-position test configurations was assessed. Both the Q3 and Hybrid III 3-year-old dummies were calibrated to their respective specifications. The Hybrid III 3-year-old met its calibration requirements, while the Q3 did not always meet its own calibration requirements. The calibration specifications of the Q3 dummy need to be re-examined and possibly refined. The biofidelity of the Q3 and Hybrid III 3-year-old dummies were evaluated in both frontal and lateral test modes. Each dummy was evaluated against its own and the other's specified requirements, when possible. In the frontal test mode, the Hybrid III 3-year-old acceptably met all of its requirements. The Q3 dummy did not meet all of its own frontal biofidelity requirements. Based on these results, the Hybrid III 3-year-old is more biofidelic for primarily frontal loading conditions. With respect to the lateral biofidelity specifications, neither the Hybrid III 3-year-old nor the Q3 dummy met the requirements for the thorax and pelvis tests performed. Both dummies met the head drop requirements. Neither dummy is recommended for lateral loading conditions. For lateral testing where only the head is impacted, the Hybrid III 3-year-old could be used. In general, the responses of both dummies were repeatable in both the frontal and lateral biofidelity tests performed. The Hybrid III 3-year-old and the Q3 dummies were evaluated in static out-of-position airbag tests with three different side airbag systems (two seat-mounted and one door-mounted system), and

  15. Head and Neck Squamous Cell Carcinomas Do Not Express EGFRvIII

    NARCIS (Netherlands)

    Melchers, Lieuwe J; Clausen, Martijn J A M; Mastik, Mirjam F; Slagter-Menkema, Lorian; Langendijk, Johannes A; van der Laan, Bernard F A M; van der Wal, Jacqueline E; van der Vegt, Bert; Roodenburg, Jan L N; Schuuring, Ed

    2014-01-01

    Purpose: To assess the prevalence of EGFRvIII, a specific variant of EGFR (epidermal growth factor receptor), in 3 well-defined cohorts of head and neck squamous cell carcinoma (HNSCC). Methods and Materials: Immunohistochemistry for the specific detection of EGFRvIII using the L8A4 antibody was opt

  16. Elective visceral hybrid repair of type III thoracoabdominal aortic aneurysm

    Directory of Open Access Journals (Sweden)

    Marjanović Ivan

    2012-01-01

    Full Text Available Introduction. According to the classification given by Crawford et al. type III thoracoabdominal aortic aneurysm (TAAA is dilatation of the aorta from the level of the rib 6 to the separation of the aorta below the renal arteries, capturing all the visceral branch of aorta. Visceral hybrid reconstruction of TAAA is a procedure developed in recent years in the world, which involves a combination of conventional, open and endovascular aortic reconstruction surgery at the level of separation of the left subclavian artery to the level of visceral branches of aorta. Case report. We presented a 75-years-old man, with elective visceral hybrid reconstruction of type III TAAA. Computerized scanning (CT angiography of the patient showed type III TAAA with the maximum transverse diameter of aneurysm of 92 mm. Aneurysm started at the level of the sixth rib, and the end of the aneurysm was 1 cm distal to the level of renal arteries. Aneurysm compressed the esophagus, causing the patient difficulty in swallowing act, especially solid food, and frequent back pain. From the other comorbidity, the patient had been treated for a long time, due to chronic obstructive pulmonary disease and hypertension. In general endotracheal anesthesia with epidural analgesia, the patient underwent visceral hybrid reconstruction of TAAA, which combines classic, open vascular surgery and endovascular procedures. Classic vascular surgery is visceral reconstruction using by-pass procedure from the distal, normal aorta to all visceral branches: celiac trunk, superior mesenteric artery and both renal arteries, with ligature of all arteries very close to the aorta. After that, by synchronous endovascular technique a complete aneurysmal exclusion of thoracoabdominal aneurysm with thoracic stent-graft was performed. The postoperative course was conducted properly and the patient left the Clinic for Vascular Surgery on postoperative day 21. Control CT, performed 3 months after the surgery

  17. Sensitivity of THOR and Hybrid III dummy lower neck loads to belt systems in frontal impact.

    Science.gov (United States)

    Yoganandan, Narayan; Pintar, Frank A; Moore, Jason; Maiman, Dennis J

    2011-02-01

    To determine head-neck biomechanics with a focus on lower neck injury metrics in frontal impact. The mid- and large-size Hybrid III dummies and the mid-size Test device for Human Occupant Restraint (THOR) were positioned on a buck. Tests were conducted at low, medium, and high (3.3, 6.7, and 15.7 m/s) change in velocities using 3 restraint types: normal 3-point belt with no pretension (type A), 10-cm pretension (type B), and 200 N pretension (type C). Repeat tests were conducted. Measured vertical and shear forces and sagittal bending moments were evaluated at the upper and lower regions of the neck to different types of belt systems and at different change in velocities. Peak values normalized with respect to the belt type A were used in the comparative analysis. Metrics transformed to the occipital condyles and T1 were also evaluated. All dummies showed good repeatability. Peak measured and transformed upper and lower neck moments were greatest in the large-size dummy. The mid-size Hybrid III dummy responded with greater forces and moments than the THOR. Regardless of dummy type, anthropometry, and velocity, peak lower neck moments were more sensitive to belt types than peak lower neck forces. A similar pattern was apparent for upper neck data. Moments in the THOR were more sensitive than moments in the mid-size Hybrid III dummy. This study offers quantitative generic restraint-based data and addresses response differences between dummies and dummies of the same family. Because of increased sensitivity to belt types at the upper and lower necks for both forces and moments, the THOR appears to be an improvement to better assess injury potential to rear seat occupants wherein frontal impact air bags do not exist.

  18. Monolithic III-V and hybrid polysilicon-III-V microelectromechanical tunable vertical-cavity surface-emitting lasers

    Science.gov (United States)

    Ochoa, Edward M.; Lott, James A.; Nelson, Thomas R., Jr.; Harvey, M. C.; Raley, J. A.; Stintz, Andreas; Malloy, Kevin J.

    2003-04-01

    We report our progress on the design and fabrication of electrostatically-actuated microelectromechanical (MEM) tunable wavelength filters and vertical cavity surface-emitting lasers (VCSELs). We investigate both an all-semiconductor monolithic approach and a hybrid approach based on the combination of conventional polysilicon microelectromechanical systems (MEMS) and III-V semiconductor thin-film distributed Bragg reflector (DBR) and VCSEL structures. In the tunable hybrid structures the III-V semiconductor layers are flip-bonded onto specially designed polysilicon foundry MEMS structures and separated from their lattice-matched parent substrates by a novel post-bonding lift-off process.

  19. Head and Neck Squamous Cell Carcinomas Do Not Express EGFRvIII

    Energy Technology Data Exchange (ETDEWEB)

    Melchers, Lieuwe J., E-mail: l.j.melchers@umcg.nl [Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Clausen, Martijn J.A.M. [Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Mastik, Mirjam F. [Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Slagter-Menkema, Lorian [Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Langendijk, Johannes A. [Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Laan, Bernard F.A.M. van der [Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Wal, Jacqueline E. van der; Vegt, Bert van der [Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Roodenburg, Jan L.N. [Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen (Netherlands); Schuuring, Ed [Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen (Netherlands)

    2014-10-01

    Purpose: To assess the prevalence of EGFRvIII, a specific variant of EGFR (epidermal growth factor receptor), in 3 well-defined cohorts of head and neck squamous cell carcinoma (HNSCC). Methods and Materials: Immunohistochemistry for the specific detection of EGFRvIII using the L8A4 antibody was optimized on formalin-fixed, paraffin-embedded tissue using glioblastoma tissue. It was compared with EGFR and EGFRvIII RNA expression using a specific reverse transcription–polymerase chain reaction also optimized for formalin-fixed, paraffin-embedded tissue. Tissue microarrays including 531 HNSCCs of various stages with complete clinicopathologic and follow-up data were tested for the presence of EGFRvIII. Results: None of the 531 cases showed EGFRvIII protein expression. Using an immunohistochemistry protocol reported by others revealed cytoplasmic staining in 8% of cases. Reverse transcription–polymerase chain reaction for the EGFRvIII transcript of the 28 highest cytoplasmic staining cases, as well as 69 negative cases, did not show expression in any of the tested cases, suggesting aspecific staining by a nonoptimal protocol. Conclusions: The EGFRvIII mutation is not present in HNSCC. Therefore, EGFRvIII does not influence treatment response in HNSCC and is not a usable clinical prognostic marker.

  20. Hybrid III-V/SOI resonant cavity enhanced photodetector

    DEFF Research Database (Denmark)

    Learkthanakhachon, Supannee; Taghizadeh, Alireza; Park, Gyeong Cheol;

    2016-01-01

    A hybrid III–V/SOI resonant-cavity-enhanced photodetector (RCE-PD) structure comprising a high-contrast grating (HCG) reflector, a hybrid grating (HG) reflector, and an air cavity between them, has been proposed and investigated. In the proposed structure, a light absorbing material is integrated...

  1. HEAD: A Hybrid Mechanism to Enforce Node Cooperation in Mobile Ad Hoc Networks

    Institute of Scientific and Technical Information of China (English)

    QUO Jianli; LIU Hongwei; DONG Jian; YANG Xiaozong

    2007-01-01

    Mobile ad hoc networks rely on the cooperation of nodes for routing and forwarding. However, it may not be advantageous for individual nodes to cooperate. In order to make the mobile ad hoc network more robust, we propose a scheme called HEAD (a hybrid mechanism to enforce node cooperation in mobile ad hoc networks) to make the misbehavior unattractive. HEAD is an improvement to OCEAN (observation-based cooperation enforcement in ad hoc networks). It employs only first hand information and works on the top of DSR (dynamic source routing) protocol. By interacting with the DSR, HEAD can detect the misbehavior nodes in the packet forwarding process and isolate them in the route discovery process. In order to detect the misbehavior nodes quickly, HEAD introduces the warning message. In this paper, we also classify the misbehavior nodes into three types: malicious nodes, misleading nodes, and selfish nodes. They all can be detected by HEAD, and isolated from the network.

  2. Assessment of the optic nerve head parameters using Heidelberg retinal tomography III in preterm children.

    Directory of Open Access Journals (Sweden)

    Salem Alshaarawi

    Full Text Available BACKGROUND: Variations in optic nerve head morphology and abnormal retinal vascular pattern have been described in preterm children using digital image analysis of fundus photograph, optical coherence tomograph and serial funduscopy. We aimed to compare the optic nerve head parameters in preterm and term Malay children using Heidelberg Retinal Tomograph III. DESIGN: A cross sectional study. METHODOLOGY/PRINCIPAL FINDINGS: Thirty-two preterm Malay children who were born at up to 32 weeks postconception, and 32 term Malay children aged 8-16 years old were recruited into this cross sectional study, which was conducted in the Hospital Universiti Sains Malaysia, Malaysia from January to December 2011. Their optic nerves were scanned and analyzed using a Heidelberg Retinal Tomography (HRT III (Heidelberg Engineering, Germany. Preterm children showed an increased rim volume (SD (0.56 (0.26 vs 0.44 (0.18 mm(3, respectively, smaller cup shape (SD (0.18 (0.07 vs 0.25 (0.06 mm, respectively, increased height variation contour (SD (0.44 (0.14 vs 0.35 (0.08 mm, respectively, and increased cup depth (SD (0.24 (0.11 vs 0.17 (0.05 mm(3, respectively when compared to their normal peers (p0.05 in our study. CONCLUSIONS/SIGNIFICANCE: Preterm children exhibit different characteristics of optic nerve head parameters with HRT III analysis. Increased cup depth in preterm children suggests a need for close observation and monitoring. It may raise suspicion of pediatric glaucoma when proper documentation of intraocular pressure and clinical funduscopy are unsuccessful in uncooperative children.

  3. Enhanced FAA-hybrid III numerical dummy model in Madymo for aircraft occupant safety assessment

    NARCIS (Netherlands)

    Boucher, H.; Waagmeester, C.D.

    2003-01-01

    To improve survivability and to minimize the risk of injury to occupants in helicopter crash events, a complete Cabin Safety System concept including safety features and an enhanced FAA-Hybrid III dummy were developed within the HeliSafe project. A numerical tool was also created and validated to al

  4. Hybrid head-tracker being examined for the high-accuracy attack rotorcraft market

    Science.gov (United States)

    Blanton, Buddy

    2002-08-01

    The need for the helmet-mounted display (HMD) to present flight, navigation, and weapon information in the pilot's line-of-sight has continued to rise as helicopter missions increase in complexity. To obtain spatial correlation of the direction of the head line-of-sight and pilotage imagery generated from helicopter-mounted sensors, it is necessary to slave the sensors to the head motion. To accomplish this task, a head-tracking system (HTS) must be incorporated into the HMD. There are a variety of techniques that could be applied for locating the position and attitude of a helmet-mounted display. Regardless of the technology, an HTS must provide defined measurements of accuracy. System parameters include motion box size, angular range, pointing angle accuracy, pointing angle resolution, update rate, and slew rate. This paper focuses on a hybrid tracker implementation in which a combination of optical and inertial tracking using strap-down gyros is preferred. Specifically, this tracker implementation is being examined for the high-accuracy attack rotorcraft market which requires a high degree of accuracy. The performance and resultant cost of the tracker components are determined by the specific needs of the intended application. The paper will also indicate how the various requirements drive the cost, configuration, and performance of the resultant hybrid head-tracker.

  5. Enhanced non-radiative energy transfer in hybrid III-nitride structures

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R. M.; Athanasiou, M.; Bai, J.; Liu, B.; Wang, T., E-mail: t.wang@sheffield.ac.uk [Department of Electrical and Electronic Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD (United Kingdom)

    2015-09-21

    The effect of surface states has been investigated in hybrid organic/inorganic white light emitting structures that employ high efficiency, nearfield non-radiative energy transfer (NRET) coupling. The structures utilize blue emitting InGaN/GaN multiple quantum well (MQW) nanorod arrays to minimize the separation with a yellow emitting F8BT coating. Surface states due to the exposed III-nitride surfaces of the nanostructures are found to reduce the NRET coupling rate. The surface states are passivated by deposition of a silicon nitride layer on the III-nitride nanorod surface leading to reduced surface recombination. A low thickness surface passivation is shown to increase the NRET coupling rate by 4 times compared to an un-passivated hybrid structure. A model is proposed to explain the increased NRET rate for the passivated hybrid structures based on the reduction in surface electron depletion of the passivated InGaN/GaN MQW nanorods surfaces.

  6. Enhanced non-radiative energy transfer in hybrid III-nitride structures

    Science.gov (United States)

    Smith, R. M.; Athanasiou, M.; Bai, J.; Liu, B.; Wang, T.

    2015-09-01

    The effect of surface states has been investigated in hybrid organic/inorganic white light emitting structures that employ high efficiency, nearfield non-radiative energy transfer (NRET) coupling. The structures utilize blue emitting InGaN/GaN multiple quantum well (MQW) nanorod arrays to minimize the separation with a yellow emitting F8BT coating. Surface states due to the exposed III-nitride surfaces of the nanostructures are found to reduce the NRET coupling rate. The surface states are passivated by deposition of a silicon nitride layer on the III-nitride nanorod surface leading to reduced surface recombination. A low thickness surface passivation is shown to increase the NRET coupling rate by 4 times compared to an un-passivated hybrid structure. A model is proposed to explain the increased NRET rate for the passivated hybrid structures based on the reduction in surface electron depletion of the passivated InGaN/GaN MQW nanorods surfaces.

  7. HYBRID APPROACH FOR OPTIMAL CLUSTER HEAD SELECTION IN WSN USING LEACH AND MONKEY SEARCH ALGORITHMS

    Directory of Open Access Journals (Sweden)

    T. SHANKAR

    2017-02-01

    Full Text Available Wireless Sensor Networks (WSNs are being widely used with low-cost, lowpower, multifunction sensors based on the development of wireless communication, which has enabled a wide variety of new applications. In WSN, the main concern is that it contains a limited power battery and is constrained in energy consumption hence energy and lifetime are of paramount importance. To achieve high energy efficiency and prolong network lifetime in WSNs, clustering techniques have been widely adopted. The proposed algorithm is hybridization of well-known Low-Energy Adaptive Clustering Hierarchy (LEACH algorithm with a distinctive Monkey Search (MS algorithm, which is an optimization algorithm used for optimal cluster head selection. The proposed hybrid algorithm exhibit high throughput, residual energy and improved lifetime. Comparison of the proposed hybrid algorithm is made with the well-known cluster-based protocols for WSNs, namely, LEACH and monkey search algorithm, individually.

  8. Evaluation of the hybrid III and Q-series pediatric ATD upper neck loads as compared to pediatric volunteers in low-speed frontal crashes.

    Science.gov (United States)

    Seacrist, Thomas; Mathews, Emily A; Balasubramanian, Sriram; Maltese, Matthew R; Arbogast, Kristy B

    2013-11-01

    Debate exists in the automotive community regarding the validity of the pediatric ATD neck response and corresponding neck loads. Previous research has shown that the pediatric ATDs exhibit hyper-flexion and chin-to-chest contact resulting in overestimations of neck loads and neck injury criteria. Our previous work comparing the kinematics of the Hybrid III and Q-series 6 and 10-year-old ATDs to pediatric volunteers in low-speed frontal sled tests revealed decreased ATD cervical and thoracic spine excursions. These kinematic differences may contribute to the overestimation of upper neck loads by the ATD. The current study compared upper neck loads of the Hybrid III and Q-series 6 and 10-year-old ATDs against size-matched male pediatric volunteers in low-speed frontal sled tests. A 3-D near-infrared target tracking system quantified the position of markers on the ATD and pediatric volunteers (head top, nasion, bilateral external auditory meatus). Shear force (F x ), axial force (F z ), bending moment (M y ), and head angular acceleration ([Formula: see text]) were calculated about the upper neck using standard equations of motion. In general, the ATDs underestimated axial force and overestimated bending moment compared to the human volunteers. The Hybrid III 6, Q6, and Q10 exhibited reduced head angular acceleration and modest increases in upper neck shear compared to the pediatric volunteers. The reduction in axial force and bending moment has important implications for neck injury predictions as both are used when calculating N ij . These analyses provide insight into the biofidelity of the pediatric ATD upper neck loads in low-speed crash environments.

  9. Zirconia-based luminescent organic-inorganic hybrid materials with ternary europium (III) complexes bonded

    Science.gov (United States)

    Yang, Jing; Li, Zhiqiang; Xu, Yang; Wang, Yige

    2016-05-01

    In this work, a novel red-emitting organic-inorganic hybrid material with europium (III) lanthanide β-diketonate complexes linked to a zirconia was reported, which was realized by adduct formation with zirconia-tethered terpyridine moieties. Luminescence enhancement of the hybrid material has been observed compared with pure Eu(tta)3·2H2O. Transparent and strongly luminescent thin films based on PMMA were also prepared at room temperature, which are highly luminescent under UV-light irradiation and possess a promising prospect in the area of optics.

  10. Comparison between radial head arthroplasty and open reduction and internal fixation in patients with radial head fractures (modified Mason type III and IV): a meta-analysis.

    Science.gov (United States)

    Sun, Hao; Duan, Jun; Li, Fengsheng

    2016-04-01

    Open reduction and internal fixation (ORIF) and radial head arthroplasty (RHA) are the most common operative treatments in patients with radial head fractures. The purpose of this study was to determine the efficacy of RHA and ORIF treatments in patients with radial head fractures (modified Mason type III and IV). We conducted a computerized search of five electronic databases from their inception to July 2015. All clinical trials comparing ORIF versus RHA treatment in patients with radial head fractures were included. We evaluated the primary outcomes included elbow functional evaluation criteria by Broberg and Morrey, elbow score (Broberg and Morrey), Mayo Elbow Performance Score (MEPS) and QuickDASH score. Secondary outcomes included Visual Analog Scale (VAS), range of motion, operation time and complications. The "assessing risk of bias" table was applied to assess the risk of bias of the included studies. Eight studies were included in this meta-analysis, which consisted of 138 cases of ORIF and 181 RHA. Methodological quality of the studies was moderate to low. RHA afforded significantly higher satisfaction rate, better elbow score (Broberg and Morrey) and MEPS, shorter operation time, lower incidence of bone nonunion or absorption and internal fixation failure when compared to ORIF. There were no significantly differences in QuickDASH score and other complications. RHA has better outcome in patients with radial head fractures (modified Mason type III and IV) than ORIF with medium-short-term follow-up period, but longer-term studies will be required to ascertain whether the apparent benefits of RHA were offset by late complications. Therapeutic decision analysis; a meta-analysis, Level III.

  11. Laboratory Reconstructions of Real World Frontal Crash Configurations using the Hybrid III and THOR Dummies and PMHS.

    Science.gov (United States)

    Petitjean, Audrey; Lebarbe, Matthieu; Potier, Pascal; Trosseille, Xavier; Lassau, Jean-Pierre

    2002-11-01

    Load-limiting belt restraints have been present in French cars since 1995. An accident study showed the greater effectiveness in thorax injury prevention using a 4 kN load limiter belt with an airbag than using a 6 kN load limiter belt without airbag. The criteria for thoracic tolerance used in regulatory testing is the sternal deflection for all restraint types, belt and/or airbag restraint. This criterion does not assess the effectiveness of the restraint 4 kN load limiter belt with airbag observed in accidentology. To improve the understanding of thoracic tolerance, frontal sled crashes were performed using the Hybrid III and THOR dummies and PMHS. The sled configuration and the deceleration law correspond to those observed in the accident study. Restraint conditions evaluated are the 6 kN load-limiting belt and the 4 kN load-limiting belt with an airbag. Loads between the occupant and the sled environment were recorded. Various measurements (including thoracic deflections and head, thorax and pelvis accelerations and angular velocities on the dummies) characterize the dummy and PMHS behavior. PMHS anthropometry and injuries were noted. This study presents the test methodology and the results used to evaluate dummy ability to discriminate both restraint types and dummy measurement ability to be representative of thoracic injury risk for all restraint types. The injury results of the PMHS tests showed the same tendency as the accident study. Some of the criteria proposed in the literature did not show a better protection of the 4 kN load limiter belt with airbag restraint, in particular thoracic deflection maxima for both dummies. The four thoracic deflections measured on the THOR and Hybrid III dummies may allow more accurate analysis of the loading pattern and therefore of injury risk.

  12. Development of a Deflection Measurement System for the Hybrid III Six-Year Old Biofidelic Abdomen

    OpenAIRE

    2012-01-01

    Despite advancements in automotive safety, motor vehicle collisions remain the leading cause of unintentional death for children ages 5 to 14. Enhancement of child occupant protection depends on the ability to accurately assess the effectiveness of restraint systems. Booster seat design and proper belt fit require evaluation using child anthropomorphic test devices, yet biofidelity of the abdomen and pelvis of the current anthropomorphic test device, the Hybrid III 6-year-old, needs improveme...

  13. Hybridization among Arctic white-headed gulls (Larus spp.) obscures the genetic legacy of the Pleistocene

    Science.gov (United States)

    Sonsthagen, Sarah A.; Chesser, R. Terry; Bell, Douglas A.; Dove, Carla J.

    2012-01-01

    We studied the influence of glacial oscillations on the genetic structure of seven species of white-headed gull that breed at high latitudes (Larus argentatus, L. canus, L. glaucescens, L. glaucoides, L. hyperboreus, L. schistisagus, and L. thayeri). We evaluated localities hypothesized as ice-free areas or glacial refugia in other Arctic vertebrates using molecular data from 11 microsatellite loci, mitochondrial DNA (mtDNA) control region, and six nuclear introns for 32 populations across the Holarctic. Moderate levels of genetic structure were observed for microsatellites (FST= 0.129), introns (ΦST= 0.185), and mtDNA control region (ΦST= 0.461), with among-group variation maximized when populations were grouped based on subspecific classification. Two haplotype and at least two allele groups were observed across all loci. However, no haplotype/allele group was composed solely of individuals of a single species, a pattern consistent with recent divergence. Furthermore, northernmost populations were not well differentiated and among-group variation was maximized when L. argentatus and L. hyberboreus populations were grouped by locality rather than species, indicating recent hybridization. Four populations are located in putative Pleistocene glacial refugia and had larger t estimates than the other 28 populations. However, we were unable to substantiate these putative refugia using coalescent theory, as all populations had genetic signatures of stability based on mtDNA. The extent of haplotype and allele sharing among Arctic white-headed gull species is noteworthy. Studies of other Arctic taxa have generally revealed species-specific clusters as well as genetic structure within species, usually correlated with geography. Aspects of white-headed gull behavioral biology, such as colonization ability and propensity to hybridize, as well as their recent evolutionary history, have likely played a large role in the limited genetic structure observed.

  14. Epidermal growth factor receptor targeted therapy in stages III and IV head and neck cancer.

    Science.gov (United States)

    Cripps, C; Winquist, E; Devries, M C; Stys-Norman, D; Gilbert, R

    2010-06-01

    What are the benefits associated with the use of anti-epidermal growth factor receptor (anti-EGFR) therapies in squamous cell carcinoma of the head and neck (HNSCC)? Anti-EGFR therapies of interest included cetuximab, gefitinib, lapatinib, zalutumumab, erlotinib, and panitumumab. Head-and-neck cancer includes malignant tumours arising from a variety of sites in the upper aerodigestive tract. The most common histologic type is squamous cell carcinoma, and most common sites are the oral cavity, the oropharynx, the hypopharynx, and the larynx. Worldwide, HNSCC is the sixth most common neoplasm, and despite advances in therapy, long-term survival in HNSCC patients is poor. Primary surgery followed by chemoradiation, or primary chemoradiation, are the standard treatment options for patients with locally advanced (stages III-IVB) HNSCC; however, meta-analytic data indicate that the benefit of concurrent platinum-based chemotherapy disappears in patients over the age of 70 years. Cetuximab is a monoclonal antibody approved for use in combination with radiation in the treatment of patients with untreated locally advanced HNSCC and as monotherapy for patients with recurrent or metastatic (stage IVC) HNSCC who have progressed on platinum-based therapy. Given the interest in anti-EGFR agents in advanced HNSCC, the Head and Neck Cancer Disease Site Group (DSG) of Cancer Care Ontario's Program in Evidence-Based Care (PEBC) chose to systematically review the literature pertaining to this topic so as to develop evidence-based recommendations for treatment. Outcomes of interest included overall and progression-free survival, quality of life, tumour response rate and duration, and the toxicity associated with the use of anti-EGFR therapies. The medline, embase, and Cochrane Library databases, the American Society of Clinical Oncology online conference proceedings, the Canadian Medical Association InfoBase, and the National Guidelines Clearinghouse were systematically searched to

  15. Roles of chemoradio therapy for stage III or IV advanced head and neck cancers

    Energy Technology Data Exchange (ETDEWEB)

    Tachikawa, Takuya; Iwai, Hiroshi; Tsuji, Hiroyuki; Minamino, Masayuki; Yamamoto, Takashi; Yukawa, Hisaya; Inoue, Toshiya; Yamashita, Toshio [Kansai Medical School, Moriguchi, Osaka (Japan)

    2002-03-01

    The effectiveness of chemoradio therapy (CRT), which was performed on 31 patients with advanced head and neck cancers of stage III or IV at Kansai Medical University between September 1999 and December 2000, was examined. The CRT consisted of continuous infusion of 5FU (500 mg/m{sup 2}) for 120 hours, prior to drip infusion of CDDP (50 mg/m{sup 2}) for 2 hours and conventional radiotherapy (2 Gy/day, 5 days/w). The 31 patients with these cancers were divided into two groups; a non-operative group (16 patients) and an operative group (15 patients). The patients in the non-operative group (16 patients) and an operative group (15 patients). The patients in the non-operative group underwent CRT (60-70 Gy of total radiation dose and two courses of chemotherapy) without surgery. The patients in the operative group received surgical treatment followed by CRT (40 Gy of total radiation dose and one course of chemotherapy). The results of CRT indicated 87.1% of the response rate (RR), and 29.0% of the complete response rate (CR) in the group. The CR rate was lower than in other reports. However, the combination of CRT and the subsequent operation indicated a disease-free survival rate of 61.3% and reduction of the recurrence rate to 17.4%. Eight of 9 patients of CR after CRT without surgery revealed NED. On the other hand, the results indicated that all 10 patients of PR after CRT showed tumor residue, 9 of 10 patients of PR showed NED after additional surgery. Therefore, it is likely that the patients of CR do not need the additional surgery, however, the patients of PR are strongly recommended the surgery to improve the local control rate as well as survival rate. Although adverse reactions of CRT on patients included mucositis, leucopenia, thrombopenia and dermatitis, the symptoms ranged within grade 3. (author)

  16. Efficient, tunable flip-chip-integrated III-V/Si hybrid external-cavity laser array.

    Science.gov (United States)

    Lin, Shiyun; Zheng, Xuezhe; Yao, Jin; Djordjevic, Stevan S; Cunningham, John E; Lee, Jin-Hyoung; Shubin, Ivan; Luo, Ying; Bovington, Jock; Lee, Daniel Y; Thacker, Hiren D; Raj, Kannan; Krishnamoorthy, Ashok V

    2016-09-19

    We demonstrate a surface-normal coupled tunable hybrid silicon laser array for the first time using passively-aligned, high-accuracy flip chip bonding. A 2x6 III-V reflective semiconductor optical amplifier (RSOA) array with integrated total internal reflection mirrors is bonded to a CMOS SOI chip with grating couplers and silicon ring reflectors to form a tunable hybrid external-cavity laser array. Waveguide-coupled wall plug efficiency (wcWPE) of 2% and output power of 3 mW has been achieved for all 12 lasers. We further improved the performance by reducing the thickness of metal/dielectric stacks and achieved 10mW output power and 5% wcWPE with the same integration techniques. This non-invasive, one-step back end of the line (BEOL) integration approach provides a promising solution to high density laser sources for future large-scale photonic integrated circuits.

  17. A hybrid algorithm for selecting head-related transfer function based on similarity of anthropometric structures

    Science.gov (United States)

    Zeng, Xiang-Yang; Wang, Shu-Guang; Gao, Li-Ping

    2010-09-01

    As the basic data for virtual auditory technology, head-related transfer function (HRTF) has many applications in the areas of room acoustic modeling, spatial hearing and multimedia. How to individualize HRTF fast and effectively has become an opening problem at present. Based on the similarity and relativity of anthropometric structures, a hybrid HRTF customization algorithm, which has combined the method of principal component analysis (PCA), multiple linear regression (MLR) and database matching (DM), has been presented in this paper. The HRTFs selected by both the best match and the worst match have been applied into obtaining binaurally auralized sounds, which are then used for subjective listening experiments and the results are compared. For the area in the horizontal plane, the localization results have shown that the selection of HRTFs can enhance the localization accuracy and can also abate the problem of front-back confusion.

  18. Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

    Science.gov (United States)

    2017-07-07

    Head and Neck Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant; Stage III Hypopharyngeal Squamous Cell Carcinoma; Stage III Laryngeal Squamous Cell Carcinoma; Stage III Laryngeal Verrucous Carcinoma; Stage III Oral Cavity Squamous Cell Carcinoma; Stage III Oral Cavity Verrucous Carcinoma; Stage III Oropharyngeal Squamous Cell Carcinoma; Stage IVA Hypopharyngeal Squamous Cell Carcinoma; Stage IVA Laryngeal Squamous Cell Carcinoma; Stage IVA Laryngeal Verrucous Carcinoma; Stage IVA Oral Cavity Squamous Cell Carcinoma; Stage IVA Oral Cavity Verrucous Carcinoma; Stage IVA Oropharyngeal Squamous Cell Carcinoma

  19. Biofidelity Evaluation of a Prototype Hybrid III 6 Year-Old ATD Lower Extremity.

    Science.gov (United States)

    Boucher, Laura C; Bing, Julie; Bolte, John H

    2016-09-01

    Incomplete instrumentation and a lack of biofidelity in the extremities of the 6 year-old anthropomorphic test device (ATD) pose challenges when studying regions of the body known to interact with the vehicle interior. This study sought to compare a prototype Hybrid III 6 year-old ATD leg (ATD-LE), with a more biofidelic ankle and tibia load cell, to previously collected child volunteer data and to the current Hybrid III 6 year-old ATD (HIII). Anthropometry, range of motion (ROM), and stiffness measurements were taken, along with a dynamic evaluation of the ATD-LE using knee-bolster airbag (KBA) test scenarios. Anthropometry values were similar in eight of twelve measurements. Total ankle ROM was improved in the ATD-LE with no bumper compared to the HIII. The highest tibia moments and tibia index values were recorded in KBA scenarios when the toes were positioned in contact with the dashboard prior to airbag deployment, forcing the ankle into axial loading and dorsiflexion. While improvements in the biofidelity of the ATD-LE are still necessary, the results of this study are encouraging. Continued advancement of the 6 year-old ATD ankle is necessary to provide a tool to directly study the behavior of the leg during a motor vehicle crash.

  20. Comparison of Hybrid III child test dummies to pediatric PMHS in blunt thoracic impact response.

    Science.gov (United States)

    Parent, D P; Crandall, J R; Bolton, J R; Bass, C R; Ouyang, J; Lau, S H

    2010-08-01

    The limited availability of pediatric biomechanical impact response data presents a significant challenge to the development of child dummies. In the absence of these data, the development of the current generation of child dummies has been driven by scaling of the biomechanical response requirements of the existing adult test dummies. Recently published pediatric blunt thoracic impact response data provide a unique opportunity to evaluate the efficacy of these scaling methodologies. However, the published data include several processing anomalies and nonphysical features. These features are corrected by minimizing instrumentation and processing error to improve the fidelity of the individual force-deflection responses. Using these data, biomechanical impact response corridors are calculated for a 3-year-old child and a 6-year-old child. These calculated corridors differ from both the originally published postmortem human subject (PMHS) corridors and the impact response requirements of the current child dummies. Furthermore, the response of the Hybrid III 3-year-old test dummy in the same impact condition shows a similar deflection but a significantly higher force than the 3-year-old corridor. The response of the Hybrid III 6-year-old dummy, on the other hand, correlates well with the calculated 6-year-old corridor. The newly developed 3-year-old and 6-year-old blunt thoracic impact response corridors can be used to define data-driven impact response requirements as an alternative to scaling-driven requirements.

  1. Incidence of Head Smut Sporisorium reilianum (Kühn) Langdon and Fullerton in Sorghum [Sorghum bicolor (L.) Moench.] Hybrids with A1 and A2 Cytoplasms

    OpenAIRE

    Víctor Pecina Quintero; Héctor Williams Alanís; Noé Montes García; Raúl Rodríguez Herrera; Enrique Rosales Robles; Víctor Antonio Vidal Martínez

    2004-01-01

    The relationship of cytoplasm type and field resistance to head smut (Sporisorium reilianum), was studied in grain sorghum. Disease incidence at grain physiological maturity was registered on sixteen hybrids in two different cytoplasms (A1 and A2) for a total of 32 hybrids. Sorghum hybrids were grown in El Tapon, Tamaulipas, Mexico, under rainfed conditions from 1990 to 1994, in fields with natural infestation of head smut. Physiological races of the fungus were determined by differential s...

  2. Europium (III) Organic Complexes in Porous Boron Nitride Microfibers: Efficient Hybrid Luminescent Material

    Science.gov (United States)

    Lin, Jing; Feng, Congcong; He, Xin; Wang, Weijia; Fang, Yi; Liu, Zhenya; Li, Jie; Tang, Chengchun; Huang, Yang

    2016-09-01

    We report the design and synthesis of a novel kind of organic-inorganic hybrid material via the incorporation of europium (III) β-diketonate complexes (Eu(TTA)3, TTA = 2-thenoyltrifluoroacetone) into one-dimensional (1D) porous boron nitride (BN) microfibers. The developed Eu(TTA)3@BN hybrid composites with typical 1D fibrous morphology exhibit bright visible red-light emission on UV illumination. The confinement of Eu(TTA)3 within pores of BN microfibers not only decreases the aggregation-caused quenching in solid Eu(TTA)3, but also improves their thermal stabilities. Moreover, The strong interactions between Eu(TTA)3 and porous BN matrix result in an interesting energy transfer process from BN host to TTA ligand and TTA ligand to Eu3+ ions, leading to the remarkable increase of red emission. The synthetic approach should be a very promising strategy which can be easily expanded to other hybrid luminescent materials based on porous BN.

  3. Europium (III) Organic Complexes in Porous Boron Nitride Microfibers: Efficient Hybrid Luminescent Material

    Science.gov (United States)

    Lin, Jing; Feng, Congcong; He, Xin; Wang, Weijia; Fang, Yi; Liu, Zhenya; Li, Jie; Tang, Chengchun; Huang, Yang

    2016-01-01

    We report the design and synthesis of a novel kind of organic-inorganic hybrid material via the incorporation of europium (III) β-diketonate complexes (Eu(TTA)3, TTA = 2-thenoyltrifluoroacetone) into one-dimensional (1D) porous boron nitride (BN) microfibers. The developed Eu(TTA)3@BN hybrid composites with typical 1D fibrous morphology exhibit bright visible red-light emission on UV illumination. The confinement of Eu(TTA)3 within pores of BN microfibers not only decreases the aggregation-caused quenching in solid Eu(TTA)3, but also improves their thermal stabilities. Moreover, The strong interactions between Eu(TTA)3 and porous BN matrix result in an interesting energy transfer process from BN host to TTA ligand and TTA ligand to Eu3+ ions, leading to the remarkable increase of red emission. The synthetic approach should be a very promising strategy which can be easily expanded to other hybrid luminescent materials based on porous BN. PMID:27687246

  4. Constitutive expression of the xylanase inhibitor TAXI-III delays Fusarium head blight symptoms in durum wheat transgenic plants.

    Science.gov (United States)

    Moscetti, Ilaria; Tundo, Silvio; Janni, Michela; Sella, Luca; Gazzetti, Katia; Tauzin, Alexandra; Giardina, Thierry; Masci, Stefania; Favaron, Francesco; D'Ovidio, Renato

    2013-12-01

    Cereals contain xylanase inhibitor (XI) proteins which inhibit microbial xylanases and are considered part of the defense mechanisms to counteract microbial pathogens. Nevertheless, in planta evidence for this role has not been reported yet. Therefore, we produced a number of transgenic plants constitutively overexpressing TAXI-III, a member of the TAXI type XI that is induced by pathogen infection. Results showed that TAXI-III endows the transgenic wheat with new inhibition capacities. We also showed that TAXI-III is correctly secreted into the apoplast and possesses the expected inhibition parameters against microbial xylanases. The new inhibition properties of the transgenic plants correlate with a significant delay of Fusarium head blight disease symptoms caused by Fusarium graminearum but do not significantly influence leaf spot symptoms caused by Bipolaris sorokiniana. We showed that this contrasting result can be due to the different capacity of TAXI-III to inhibit the xylanase activity of these two fungal pathogens. These results provide, for the first time, clear evidence in planta that XI are involved in plant defense against fungal pathogens and show the potential to manipulate TAXI-III accumulation to improve wheat resistance against F. graminearum.

  5. Comparison of head impact location during games and practices in Division III men's lacrosse players.

    Science.gov (United States)

    O'Day, Kathleen M; Koehling, Elizabeth M; Vollavanh, Lydia R; Bradney, Debbie; May, James M; Breedlove, Katherine M; Breedlove, Evan L; Blair, Price; Nauman, Eric A; Bowman, Thomas G

    2017-03-01

    Head impacts have been studied extensively in football, but little similar research has been conducted in men's lacrosse. It is important to understand the location and magnitude of head impacts during men's lacrosse to recognize the risk of head injury. Descriptive epidemiology study set on collegiate lacrosse fields. Eleven men's lacrosse players (age=20.9±1.13years, mass=83.91±9.04kg, height=179.88±5.99cm) volunteered to participate. We applied X2 sensors behind the right ear of participants for games and practices. Sensors recorded data on linear and rotational accelerations and the location of head impacts. We calculated incidence rates per 1000 exposures with 95% confidence intervals for impact locations and compared the effect of impact location on linear and rotational accelerations with Kruskal-Wallis tests. We verified 167 head impacts (games=112; practices=55). During games, the incidence rate was 651.16 (95% confidence interval=530.57-771.76). The high and low incidence rates for head impact locations during games were: side=410.7 (95% confidence interval=292.02-529.41) and top=26.79 (95% confidence interval=3.53-57.10). For games and practices combined, the impact locations did not significantly affect linear (χ(2)3=6.69, P=0.08) or rotational acceleration (χ(2)3=6.34, P=0.10). We suggest further research into the location of head impacts during games and practices. We also suggest player and coach education on head impacts as well as behavior modification in men's lacrosse athletes to reduce the incidence of impacts to the side of the head in an effort to reduce potential injury. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer

    Science.gov (United States)

    2017-09-21

    Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Verrucous Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Verrucous Carcinoma of the Larynx; Tongue Cancer

  7. Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

    NARCIS (Netherlands)

    Haigentz, Missak; Hartl, Dana M.; Silver, Carl E.; Langendijk, Johannes A.; Strojan, Primoz; Paleri, Vinidh; de Bree, Remco; Machiels, Jean-Pascal; Hamoir, Marc; Rinaldo, Alessandra; Paccagnella, Daniela; Shaha, Ashok R.; Takes, Robert P.; Ferlito, Alfio

    2012-01-01

    Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with

  8. Deflection measurement system for the hybrid iii six-year-old biofidelic abdomen.

    Science.gov (United States)

    Gregory, T Stan; Howes, Meghan K; Rouhana, Stephen W; Hardy, Warren N

    2012-01-01

    Motor vehicle collisions are the leading cause of death for children ages 5 to 14. Enhancement of child occupant protection is partly dependent on the ability to accurately assess the interaction of child-size occupants with restraint systems. Booster seat design and belt fit are evaluated using child anthropomorphic test devices, such as the Hybrid III 6-year-old dummy., A biofidelic abdomen for the Hybrid III 6-year-old dummy is being developed by the Ford Motor Company to enhance the dummy’s ability to assess injury risk and further quantify submarining risk by measuring abdominal deflection. A practical measurement system for the biofidelic abdominal insert has been developed and demonstrated for three dimensional determination of abdominal deflection. Quantification of insert deflection is achieved via differential signal measurement using electrodes mounted within a conductive medium. Signal amplitude is proportional to the distance between the electrodes. A microcontroller is used to calculate distances between ventral electrodes and a dorsal electrode in three dimensions. This system has been calibrated statically, and its performance demonstrated in a series of sled tests. Deflection measurements from the instrumented abdominal insert indicate performance differences between two booster seat designs, yielding an average peak anterior to posterior displacement of the abdomen of 1.0 ± 3.4 mm and 31.2 ± 7.2 mm for the seats, respectively. Implementation of a 6-year-old abdominal insert with the ability to evaluate submarining potential will likely help safety researchers further enhance booster seat design and interaction with vehicle restraint systems , and help to further understand child occupant injury risk in automobile collisions.

  9. Realization of back-side heterogeneous hybrid III-V/Si DBR lasers for silicon photonics

    Science.gov (United States)

    Durel, Jocelyn; Ferrotti, Thomas; Chantre, Alain; Cremer, Sébastien; Harduin, Julie; Bernabé, Stéphane; Kopp, Christophe; Boeuf, Frédéric; Ben Bakir, Badhise; Broquin, Jean-Emmanuel

    2016-02-01

    In this paper, the simulation, design and fabrication of a back-side coupling (BSC) concept for silicon photonics, which targets heterogeneous hybrid III-V/Si laser integration is presented. Though various demonstrations of a complete SOI integration of passive and active photonic devices have been made, they all feature multi-level planar metal interconnects, and a lack of integrated light sources. This is mainly due to the conflict between the need of planar surfaces for III-V/Si bonding and multiple levels of metallization. The proposed BSC solution to this topographical problem consists in fabricating lasers on the back-side of the Si waveguides using a new process sequence. The devices are based on a hybrid structure composed of an InGaAsP MQW active area and a Si-based DBR cavity. The emitted light wavelength is accordable within a range of 20 nm around 1.31μm thanks to thermal heaters and the laser output is fiber coupled through a Grating Coupler (GC). From a manufacturing point of view, the BSC approach provides not only the advantages of allowing the use of a thin-BOX SOI instead of a thick one; but it also shifts the laser processing steps and their materials unfriendly to CMOS process to the far back-end areas of fabrication lines. Moreover, aside from solving technological integration issues, the BSC concept offers several new design opportunities for active and passive devices (heat sink, Bragg gratings, grating couplers enhanced with integrated metallic mirrors, tapers…). These building boxes are explored here theoretically and experimentally.

  10. A hydro/organo/hybrid gelator: a peptide lipid with turning aspartame head groups.

    Science.gov (United States)

    Mukai, Masaru; Minamikawa, Hiroyuki; Aoyagi, Masaru; Asakawa, Masumi; Shimizu, Toshimi; Kogiso, Masaki

    2013-04-01

    This work presents a novel bola-type peptide lipid which can gelate water, organic solvents, and water/organic-solvent mixtures. In its molecular structure, an amphiphilic dipeptide aspartame (L-α-aspartyl-L-phenylalanine methyl ester) is connected at both ends of an alkylene linker. The different morphologies in the hydrogel (helical nanotapes) and the organogel (tape-like nanostructures) were visualized by energy-filtering transmission electron microscopy (EF-TEM) and energy-filtering scanning electron microscopy (FE-SEM), and the molecular arrangement was examined using X-ray diffraction (XRD), infrared (IR) spectroscopy, and circular dichroism (CD) spectroscopy. Possessing a hydrophilic aspartic acid group and a (relatively) hydrophobic phenylalanine methyl ester group, the dipeptide head group can turn about in response to solvent polarity. As a consequence, the solvent condition changed the molecular packing of the gelator and affected the overall supramolecular structure of the gel. It is noted that the peptide lipid gelated mixed solvents of water and organic solvents such as dichloromethane, liquid-paraffin, olive-oil, silicone-oils, and so on. The present hybrid gel can simultaneously hold hydrophilic and hydrophobic functional materials.

  11. Hybrid tunnel junction contacts to III-nitride light-emitting diodes

    Science.gov (United States)

    Young, Erin C.; Yonkee, Benjamin P.; Wu, Feng; Oh, Sang Ho; DenBaars, Steven P.; Nakamura, Shuji; Speck, James S.

    2016-02-01

    In this work, we demonstrate highly doped GaN p-n tunnel junction (TJ) contacts on III-nitride heterostructures where the active region of the device and the top p-GaN layers were grown by metal organic chemical vapor deposition and highly doped n-GaN was grown by NH3 molecular beam epitaxy to form the TJ. The regrowth interface in these hybrid devices was found to have a high concentration of oxygen, which likely enhanced tunneling through the diode. For optimized regrowth, the best tunnel junction device had a total differential resistivity of 1.5 × 10-4 Ω cm2, including contact resistance. As a demonstration, a blue-light-emitting diode on a (20\\bar{2}\\bar{1}) GaN substrate with a hybrid tunnel junction and an n-GaN current spreading layer was fabricated and compared with a reference sample with a transparent conducting oxide (TCO) layer. The tunnel junction LED showed a lower forward operating voltage and a higher efficiency at a low current density than the TCO LED.

  12. Kinetic and kinematic responses of post mortem human surrogates and the Hybrid III ATD in high-speed frontal sled tests.

    Science.gov (United States)

    Beeman, Stephanie M; Kemper, Andrew R; Madigan, Michael L; Duma, Stefan M

    2013-06-01

    Despite improvements in vehicle design and safety technologies, frontal automotive collisions continue to result in a substantial number of injuries and fatalities each year. Although a considerable amount of research has been performed on PMHSs and ATDs, matched dynamic whole-body frontal testing with PMHSs and the current ATD aimed at quantifying both kinetic and kinematic data in a single controlled study is lacking in the literature. Therefore, a total of 4 dynamic matched frontal sled tests were performed with three male PMHSs and a Hybrid III 50th percentile male ATD (28.6g, Δv=40 kph). Each subject was restrained using a 4 kN load limiting, driver-side, 3-point seatbelt. Belt force was measured for the lap belt and shoulder belt. Reaction forces were measured at the seat pan, seat back, independent foot plates, and steering column. Linear head acceleration, angular head acceleration, and pelvic acceleration were measured for all subjects. Acceleration of C7, T7, T12, both femurs, and both tibias were also measured for the PMHSs. A Vicon motion analysis system, consisting of 12 MX-T20 2 megapixel cameras, was used to quantify subject 3D motion (±1 mm) at a rate of 1 kHz. Excursions of select anatomical regions were normalized to their respective initial positions and compared by test condition and between subject types. Notable discrepancies were observed in the responses of the PMHSs and the ATD. The reaction forces and belt loading for the ATD, particularly foot plate, seat back, steering column, and lap belt forces, were not in agreement with those of the PMHSs. The forward excursions of the ATD were consistently within those of the PMHSs with the exception of the left upper extremity. This could potentially be due to the known limitations of the Hybrid III ATD shoulder and chest. The results presented herein demonstrate that there are some limitations to the current Hybrid III ATD under the loading conditions evaluated in the current study. Overall

  13. A Comparison of the Hybrid III and BioRID II Dummies in Low-Severity, Rear-Impact Sled Tests.

    Science.gov (United States)

    Kim, A; Anderson, K F; Berliner, J; Bryzik, C; Hassan, J; Jensen, J; Kendall, M; Mertz, H J; Morrow, T; Rao, A; Wozniak, J A

    2001-11-01

    A BioRID II dummy and a Hybrid III dummy, each representative of a midsize adult male, were tested side-by-side in simulated rear-impact sled tests. In all tests the dummies were restrained by 3-point belt systems. The results of 4 test sets conducted at a nominal change in velocity (deltaV) of 16 km/hr are presented and discussed. In three of the test sets, bucket seats were used. The head restraints were placed in the up-position in two of the three test sets and in the down-position in the third set of tests. In the fourth test set, rigid seats without any head restraints were used. While analyzing the BioRID II data, the presence of an axial neck load acting on the head, which bypassed the upper neck load transducer, was discovered in all the reported tests. The implication of this observation is that the axial force and all the moments measured by the BioRID II upper neck load transducer could be erroneous. A second concern with the BioRID II data was the high frequency noise observed, especially on the T1 acceleration response which is used in the NIC calculation. The 18 Hz filter used to process the T1 acceleration data for the NIC calculation attenuated the peak NIC values by 15% as compared to the SAE 180 filtered values. The unmeasured neck loads and high-frequency noise issues need to be resolved before additional BioRID II testing is done. A third concern with the BioRID II is the initial position of its head in the automotive seating posture. It is higher and more forward than that of the 50(th) percentile adult male.

  14. A multifunctional organic-inorganic hybrid structure based on Mn(III)-porphyrin and polyoxometalate as a highly effective dye scavenger and heterogenous catalyst.

    Science.gov (United States)

    Zou, Chao; Zhang, Zhijuan; Xu, Xuan; Gong, Qihan; Li, Jing; Wu, Chuan-De

    2012-01-11

    A two-step synthesis strategy has led to a unique layered polyoxometalate-Mn(III)-metalloporphyrin-based hybrid material. The hybrid solid demonstrates remarkable capability for scavenging of dyes and for heterogeneous selective oxidation of alkylbenzenes with excellent product yields and 100% selectivity.

  15. Bacillus thuringiensis delta-endotoxin Cry1Ac domain III enhances activity against Heliothis virescens in some, but not all Cry1-Cry1Ac hybrids

    NARCIS (Netherlands)

    Karlova, R.B.; Weemen, W.M.J.; Naimov, S.; Ceron, J.; Dukiandjiev, S.; Maagd, de R.A.

    2005-01-01

    We investigated the role of domain III of Bacillus thuringiensis d-endotoxin Cry1Ac in determining toxicity against Heliothis virescens. Hybrid toxins, containing domain III of Cry1Ac with domains I and II of Cry1Ba, Cry1Ca, Cry1Da, Cry1Ea, and Cry1Fb, respectively, were created. In this way Cry1Ca,

  16. Hybrid integration of III-V and silicon materials and devices

    Science.gov (United States)

    Luo, Zhongsheng

    Laser liftoff (LLO) based hybrid integration techniques including the double-transfer process and the pixel-to-point transfer process have been developed to integrate III-V photonics with silicon materials and circuitry. No degradation in the device performance has been observed using the LLO based transfer techniques. On the contrary, performance improvements in both electrical characteristics and electroluminescence (EL) output have been found for the (In,Ga)N light emitting diodes (LEDs) transferred onto Si substrate. Based on computer simulation, it is found that as much as 70% enhancement in EL output could be expected by optimizing the metal layering on the backside of the transferred LEDs. In order to understand the existing experimental data and improve controllability and damage-free transfer yield of the LLO process, a novel, comprehensive LLO model based on thermal-mechanical analysis has been proposed and developed. The LLO model has been validated in the well-studied GaN/sapphire system. By employing the LLO based transfer technique, two optoelectronic systems have been designed and demonstrated. The first one is an integrated fluorescence microsystem, which involved the integration of Cd(S,Se) bandgap filters, (In,Ga)N LEDs, Poly(dimethylsiloxane) (PDMS) microfluidic channels with a pre-fabricated Si PIN photodiode chip. Prototypes with both one color (blue LED) excitation and two-color (blue and green LED) excitation have consistently demonstrated a detection capability of as low as 1 nM fluosphere beads using Molecular Probes FluoSpheresRTM dye. Furthermore, the feasibility of multi-wavelength design has been verified using the bi-wavelength prototype. To optimize signal-to-noise ratio and detection sensitivity of the microsystem via system design, an in-depth mathematic analysis has also been performed. The second application is a zero-footprint optical metrology wafer, which relies on the reflection at the optical detection window, through which

  17. A mixed methods protocol for developing and testing implementation strategies for evidence-based obesity prevention in childcare: a cluster randomized hybrid type III trial.

    Science.gov (United States)

    Swindle, Taren; Johnson, Susan L; Whiteside-Mansell, Leanne; Curran, Geoffrey M

    2017-07-18

    Despite the potential to reach at-risk children in childcare, there is a significant gap between current practices and evidence-based obesity prevention in this setting. There are few investigations of the impact of implementation strategies on the uptake of evidence-based practices (EBPs) for obesity prevention and nutrition promotion. This study protocol describes a three-phase approach to developing and testing implementation strategies to support uptake of EBPs for obesity prevention practices in childcare (i.e., key components of the WISE intervention). Informed by the i-PARIHS framework, we will use a stakeholder-driven evidence-based quality improvement (EBQI) process to apply information gathered in qualitative interviews on barriers and facilitators to practice to inform the design of implementation strategies. Then, a Hybrid Type III cluster randomized trial will compare a basic implementation strategy (i.e., intervention as usual) with an enhanced implementation strategy informed by stakeholders. All Head Start centers (N = 12) within one agency in an urban area in a southern state in the USA will be randomized to receive the basic or enhanced implementation with approximately 20 classrooms per group (40 educators, 400 children per group). The educators involved in the study, the data collectors, and the biostastician will be blinded to the study condition. The basic and enhanced implementation strategies will be compared on outcomes specified by the RE-AIM model (e.g., Reach to families, Effectiveness of impact on child diet and health indicators, Adoption commitment of agency, Implementation fidelity and acceptability, and Maintenance after 6 months). Principles of formative evaluation will be used throughout the hybrid trial. This study will test a stakeholder-driven approach to improve implementation, fidelity, and maintenance of EBPs for obesity prevention in childcare. Further, this study provides an example of a systematic process to develop

  18. Operational performance of the ETH-hybrid III drive system - at the test stand and in the vehicle; Betriebsverhalten des ETH-Hybrid III Antriebes - Auf dem dynamischen Pruefstand und im Fahrzeug

    Energy Technology Data Exchange (ETDEWEB)

    Dietrich, P.; Eberle, M.K.

    1999-07-01

    The position and the way of operation of the ETH hybrid III drive system in an Otto engine, an electric motor, a flywheel and an infinitely variable wide-range transmission are presented. The consumption values for gasoline and electric power are shown for constant drive and in city cycles. The achievable conservation of 40% at gasoline operation is not limited to one cycle and shows the robustness of this measure to improve partial load operation. The sensitiveness towards the evaluated current generation is shown by means of the autarkic charge operation. (orig.) [German] Es wird die Anordnung und die Betriebsweise des ETH-Hybrid III Antriebes mit einem Ottomotor, einem Elektromotor, einem Schwungrad und einem stufenlosen Weitbereichsgetriebe dargestellt. Es werden die Verbrauchswerte bei Konstantfahrt und in Stadtzyklen sowohl fuer Benzin und Strom aufgezeigt. Die erzielbaren 40% Verbrauchseinsparung im Benzinbetrieb ist nicht nur auf einen Zyklus beschraenkt und zeigt die Robustheit dieser Teillastverbesserungsmassnahme auf. Anhand des autarken Ladebetriebes wird die Sensitivitaet gegenueber der betrachteten Stromherstellung aufgezeigt. (orig.)

  19. Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and Neck

    Science.gov (United States)

    2012-10-30

    Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx; Stage IV Verrucous Carcinoma of the Larynx; Stage IV Verrucous Carcinoma of the Oral Cavity

  20. Cisplatin, Radiation Therapy, and Pembrolizumab in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma

    Science.gov (United States)

    2016-05-16

    Stage III Hypopharyngeal Squamous Cell Carcinoma; Stage III Laryngeal Squamous Cell Carcinoma; Stage III Oral Cavity Squamous Cell Carcinoma; Stage III Oropharyngeal Squamous Cell Carcinoma; Stage IVA Hypopharyngeal Squamous Cell Carcinoma; Stage IVA Laryngeal Squamous Cell Carcinoma; Stage IVA Oral Cavity Squamous Cell Carcinoma; Stage IVA Oropharyngeal Squamous Cell Carcinoma; Stage IVB Hypopharyngeal Squamous Cell Carcinoma; Stage IVB Laryngeal Squamous Cell Carcinoma; Stage IVB Oral Cavity Squamous Cell Carcinoma; Stage IVB Oropharyngeal Squamous Cell Carcinoma

  1. Alpha Trianguli Australis (K2 II-III) - Hybrid or composite?

    Science.gov (United States)

    Ayres, T. R.

    1985-01-01

    The prototype hybrid-spectrum giant Alpha Trianguli Australis exhibits a far-ultraviolet continuum which is considerably bluer than would be expected of a star of its optical colors, suggesting the presence of a previously unrecognized companion. If the K-type primary is as luminous as indicated by the widths of its Ca II and H-alpha lines, the companion could be an early F-type dwarf that only recently has arrived on the main sequence. Indeed, the flux of C IV from Alpha TrA - an important measure of hybridness - would not be inconsistent with that expected from a very young chromospherically active F star.

  2. Biomechanics of head injury in olympic taekwondo and boxing.

    Science.gov (United States)

    Fife, G P; O'Sullivan, D; Pieter, W

    2013-12-01

    The purpose was to examine differences between taekwondo kicks and boxing punches in resultant linear head acceleration (RLA), head injury criterion (HIC15), peak head velocity, and peak foot and fist velocities. Data from two existing publications on boxing punches and taekwondo kicks were compared. For taekwondo head impacts a Hybrid II Crash Dummy (Hybrid II) head was instrumented with a tri-axial accelerometer mounted inside the Hybrid II head. The Hybrid II was fixed to a height-adjustable frame and fitted with a protective taekwondo helmet. For boxing testing, a Hybrid III Crash Dummy head was instrumented with an array of tri-axial accelerometers mounted at the head centre of gravity. Differences in RLA between the roundhouse kick (130.11±51.67 g) and hook punch (71.23±32.19 g, d = 1.39) and in HIC15 (clench axe kick: 162.63±104.10; uppercut: 24.10±12.54, d = 2.29) were observed. Taekwondo kicks demonstrated significantly larger magnitudes than boxing punches for both RLA and HIC.

  3. BIOMECHANICS OF HEAD INJURY IN OLYMPIC TAEKWONDO AND BOXING

    Science.gov (United States)

    Fife, G.P.; Pieter, W.

    2013-01-01

    Objective The purpose was to examine differences between taekwondo kicks and boxing punches in resultant linear head acceleration (RLA), head injury criterion (HIC15), peak head velocity, and peak foot and fist velocities. Data from two existing publications on boxing punches and taekwondo kicks were compared. Methods For taekwondo head impacts a Hybrid II Crash Dummy (Hybrid II) head was instrumented with a tri-axial accelerometer mounted inside the Hybrid II head. The Hybrid II was fixed to a height-adjustable frame and fitted with a protective taekwondo helmet. For boxing testing, a Hybrid III Crash Dummy head was instrumented with an array of tri-axial accelerometers mounted at the head centre of gravity. Results Differences in RLA between the roundhouse kick (130.11±51.67 g) and hook punch (71.23±32.19 g, d = 1.39) and in HIC15 (clench axe kick: 162.63±104.10; uppercut: 24.10±12.54, d = 2.29) were observed. Conclusions Taekwondo kicks demonstrated significantly larger magnitudes than boxing punches for both RLA and HIC. PMID:24744497

  4. 4 August 2011 - Austrian Head of Protocol, Directorate General III, Federal Ministry of Science and Research I. Friedrich (3rd from left) in the LHC superconducting magnet test hall with M. Benedkit, C. Wulz and C. Fabjan.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    4 August 2011 - Austrian Head of Protocol, Directorate General III, Federal Ministry of Science and Research I. Friedrich (3rd from left) in the LHC superconducting magnet test hall with M. Benedkit, C. Wulz and C. Fabjan.

  5. 77 FR 11651 - Hybrid III 10-Year-Old Child Test Dummy

    Science.gov (United States)

    2012-02-27

    ... results, the agency is pursuing the development of an HIII-10C modification consisting of an abdominal.... Executive Summary II. Background a. 2005 NPRM b. Developments Since 2005 c. Summary of Decision III. Summary... 1. Labeling the Dummy as a ``Ten Year Old'' 2. Best Practices for Belt Routing 3. Abdominal...

  6. Solar Central Receiver Hybrid Power Systems sodium-cooled receiver concept. Final report. Volume III. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    The overall, long term objective of the Solar Central Receiver Hybrid Power System is to identify, characterize, and ultimately demonstrate the viability and cost effectiveness of solar/fossil, steam Rankine cycle, hybrid power systems that: (1) consist of a combined solar central receiver energy source and a nonsolar energy source at a single, common site, (2) may operate in the base, intermediate, and peaking capacity modes, (3) produce the rated output independent of variations in solar insolation, (4) provide a significant savings (50% or more) in fuel consumpton, and (5) produce power at the minimum possible cost in mills/kWh. It is essential that these hybrid concepts be technically feasible and economically competitive with other systems in the near to mid-term time period (1985-1990) on a commercial scale. The program objective for Phase I is to identify and conceptually characterize solar/fossil steam Rankine cycle, commercial-scale, power plant systems that are economically viable and technically feasible. This volume contains appendices to the conceptual design and systems analysis studies gien in Volume II, Books 1 and 2. (WHK)

  7. Oxide-Free Bonding of III-V-Based Material on Silicon and Nano-Structuration of the Hybrid Waveguide for Advanced Optical Functions

    Directory of Open Access Journals (Sweden)

    Konstantinos Pantzas

    2015-10-01

    Full Text Available Oxide-free bonding of III-V-based materials for integrated optics is demonstrated on both planar Silicon (Si surfaces and nanostructured ones, using Silicon on Isolator (SOI or Si substrates. The hybrid interface is characterized electrically and mechanically. A hybrid InP-on-SOI waveguide, including a bi-periodic nano structuration of the silicon guiding layer is demonstrated to provide wavelength selective transmission. Such an oxide-free interface associated with the nanostructured design of the guiding geometry has great potential for both electrical and optical operation of improved hybrid devices.

  8. A Novel Cluster-head Selection Algorithm Based on Hybrid Genetic Optimization for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Lejiang Guo

    2011-05-01

    Full Text Available Wireless Sensor Networks (WSN represent a new dimension in the field of network research. The cluster algorithm can significantly reduce the energy consumption of wireless sensor networks and prolong the network lifetime. This paper uses neuron to describe the WSN node and constructs neural network model for WSN. The neural network model includes three aspects: WSN node neuron model, WSN node control model and WSN node connection model. Through learning the framework of cluster algorithm for wireless sensor networks, this paper presents a weighted average of cluster-head selection algorithm based on an improved Genetic Optimization which makes the node weights directly related to the decision-making predictions. The Algorithm consists of two stages: single-parent evolution and population evolution. The initial population is formed in the stage of single-parent evolution by using gene pool, then the algorithm continues to the next further evolution process, finally the best solution will be generated and saved in the population. The simulation results illustrate that the new algorithm has the high convergence speed and good global searching capacity. It is to effectively balance the network energy consumption, improve the network life-cycle, ensure the communication quality and provide a certain theoretical foundation for the applications of the neural networks.

  9. Comparative genomic hybridization analysis detects frequent over-representation of DNA sequences at 3q, 7p, 8q and 18q in head and neck carcinomas

    DEFF Research Database (Denmark)

    Bergamo, N A; Rogatto, S R; Poli-Frederico, R C;

    2000-01-01

    Comparative genomic hybridization (CGH) was used to identify chromosomal imbalances in 19 samples of squamous cell carcinoma of the head and neck (HNSCC). The chromosome arms most often over-represented were 3q (48%), 8q (42%), and 7p (32%); in many cases, these changes were observed at high copy...... and 2q material were detected in patients exhibiting a clinical history of recurrence and/or metastasis followed by terminal disease. This association suggests that gain of 1q and 2q may be a new marker of head and neck tumors with a refractory clinical response....

  10. Three-dimensional adult male head and skull contours.

    Science.gov (United States)

    Lee, Calvin; Loyd, Andre M; Nightingale, Roger; Myers, Barry S; Damon, Andrew; Bass, Cameron R

    2014-01-01

    Traumatic brain injury (TBI) is a major public health issue, affecting millions of people annually. Anthropomorphic test devices (ATDs) and finite element models (FEMs) provide a means of understanding factors leading to TBI, potentially reducing the occurrence. Thus, there is a need to ensure that these tools accurately model humans. For example, the Hybrid III was not based on 3-dimensional human head shape data. The objective of this study is to produce average head and skull contours for an average U.S. male that can be used for ATDs and FEMs. Computed tomography (CT) scans of adult male heads were obtained from a database provided by the University of Virginia Center for Applied Biomechanics. An orthographic viewer was used to extract head and skull contours from the CT scans. Landmarks were measured graphically using HyperMesh (Altair, HyperWorks). To determine the head occipital condyle (OC) centroid, surface meshes of the OCs were made and the centroid of the surfaces was calculated. The Hybrid III contour was obtained using a MicroScribe Digitizer (Solution Technologies, Inc., Oella, MD). Comparisons of the average male and ATD contours were performed using 2 methods: (1) the midsagittal and midcoronal ATD contours relative to the OC centroid were compared to the corresponding 1 SD range of the average male contours; (2) the ATD sagittal contour was translated relative to the average male sagittal contour to minimize the area between the 2 contours. Average male head and skull contours were created. Landmark measurements were made for the dorsum sellae, nasion skin, nasion bone, infraorbital foramen, and external auditory meatus, all relative to the OC centroid. The Hybrid III midsagittal contour was outside the 1 SD range for 15.2 percent of the average male head contour but only by a maximum distance of 1.5 mm, whereas the Hybrid III midcoronal head contour was outside the 1 SD range for 12.2 percent of the average male head contour by a maximum distance

  11. Direct electro-optical pumping for hybrid CdSe nanocrystal/III-nitride based nano-light-emitting diodes

    Science.gov (United States)

    Mikulics, M.; Arango, Y. C.; Winden, A.; Adam, R.; Hardtdegen, A.; Grützmacher, D.; Plinski, E.; Gregušová, D.; Novák, J.; Kordoš, P.; Moonshiram, A.; Marso, M.; Sofer, Z.; Lüth, H.; Hardtdegen, H.

    2016-02-01

    We propose a device concept for a hybrid nanocrystal/III-nitride based nano-LED. Our approach is based on the direct electro-optical pumping of nanocrystals (secondary excitation) by electrically driven InGaN/GaN nano-LEDs as the primary excitation source. To this end, a universal hybrid optoelectronic platform was developed for a large range of optically active nano- and mesoscopic structures. The advantage of the approach is that the emission of the nanocrystals can be electrically induced without the need of contacting them. The proof of principal was demonstrated for the electro-optical pumping of CdSe nanocrystals. The nano-LEDs with a diameter of 100 nm exhibit a very low current of ˜8 nA at 5 V bias which is several orders of magnitude smaller than for those conventionally used. The leakage currents in the device layout were typically in the range of 8 pA to 20 pA/cm2 at 5 V bias. The photon-photon down conversion efficiency was determined to be 27%. Microphotoluminescence and microelectroluminescence characterization demonstrate the potential for future optoelectronics and highly secure "green" information technology applications.

  12. Hybrid image and signal processing III; Proceedings of the Meeting, Orlando, FL, Apr. 23, 24, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Casasent, D.P.; Tescher, A.G.

    1992-01-01

    The present conference discusses the optical Gabor and wavelet transforms for image analysis, image segmentation via optical wavelets, semidifferential invariants, object labeling via convolution, tactile pattern recognition with complex linear morphology, a hybrid six-degree-of-freedom tracking system, and a hazard detection/avoidance sensor for NASA planetary landers. Also discussed are layered optical processing architectures, optoelectronic wide-world personality ROMs for high-speed control, a GaAs-based photorefractive time-integrating correlator, multispectral lossy data compression using vector quantization, broad vector quantization for transform image coding, and a mixed vendor computer architecture for precision image analysis.

  13. Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy

    Science.gov (United States)

    2013-12-10

    Mucositis; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Larynx; Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Oropharynx; Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVC Verrucous Carcinoma of the Larynx; Stage IVC Verrucous Carcinoma of the Oral

  14. Ice hockey shoulder pad design and the effect on head response during shoulder-to-head impacts.

    Science.gov (United States)

    Richards, Darrin; Ivarsson, B Johan; Scher, Irving; Hoover, Ryan; Rodowicz, Kathleen; Cripton, Peter

    2016-11-01

    Ice hockey body checks involving direct shoulder-to-head contact frequently result in head injury. In the current study, we examined the effect of shoulder pad style on the likelihood of head injury from a shoulder-to-head check. Shoulder-to-head body checks were simulated by swinging a modified Hybrid-III anthropomorphic test device (ATD) with and without shoulder pads into a stationary Hybrid-III ATD at 21 km/h. Tests were conducted with three different styles of shoulder pads (traditional, integrated and tethered) and without shoulder pads for the purpose of control. Head response kinematics for the stationary ATD were measured. Compared to the case of no shoulder pads, the three different pad styles significantly (p shoulder pads reduced linear head accelerations by an additional 18-21% beyond the other two styles of shoulder pads. The data presented here suggest that shoulder pads can be designed to help protect the head of the struck player in a shoulder-to-head check.

  15. Hybrid integration of III-V semiconductor lasers on silicon waveguides using optofluidic microbubble manipulation

    Science.gov (United States)

    Jung, Youngho; Shim, Jaeho; Kwon, Kyungmook; You, Jong-Bum; Choi, Kyunghan; Yu, Kyoungsik

    2016-07-01

    Optofluidic manipulation mechanisms have been successfully applied to micro/nano-scale assembly and handling applications in biophysics, electronics, and photonics. Here, we extend the laser-based optofluidic microbubble manipulation technique to achieve hybrid integration of compound semiconductor microdisk lasers on the silicon photonic circuit platform. The microscale compound semiconductor block trapped on the microbubble surface can be precisely assembled on a desired position using photothermocapillary convective flows induced by focused laser beam illumination. Strong light absorption within the micro-scale compound semiconductor object allows real-time and on-demand microbubble generation. After the assembly process, we verify that electromagnetic radiation from the optically-pumped InGaAsP microdisk laser can be efficiently coupled to the single-mode silicon waveguide through vertical evanescent coupling. Our simple and accurate microbubble-based manipulation technique may provide a new pathway for realizing high precision fluidic assembly schemes for heterogeneously integrated photonic/electronic platforms as well as microelectromechanical systems.

  16. Optical response of Ce(III and Eu(II doped hybrid materials synthesised by Sol-Gel processing

    Directory of Open Access Journals (Sweden)

    Cordoncillo, E.

    2000-02-01

    Full Text Available This study deals with the preparation of two hybrid organic-inorganic matrices via sol–gel, starting from alkylalkoxisilanes Si(CH3(OCH2CH33 (MTEOS–SiH(CH3(OCH2CH32 (MDES, A system, and SiH(CH3(OCH2CH32 (MDES SiH(OCH2CH33 (TREOS, B system, together with zirconium n-propoxide. Another type-A is carried out by adding acetylacetone, A-acac system. The matrices are characterised by infrared spectroscopy, nuclear magnetic resonance (NMR-MAS, and chemical analysis. Optical characteristics of the matrices have been studied. A-acac and B matrices are doped with an Eu(III salt, and A and B matrices are doped with a Ce(IV salt. Absorption and emission studies show the presence of Eu(II and Ce(III. The transition metal alkoxide that catalysed cleavage of the Si–H bonds was used to reduce in situ at room temperature, the rare earth cations. Depending on chemical strategy, the resulting hybrid materials can be processed as transparent bulks or coatings which exhibit a good transparency in the UV–visible domain. Both the undoped and the rare earth doped matrices exhibit a strong blue emission.

    En este trabajo se aborda la preparación de dos matrices híbridas orgánico-inorgánicas por vía sol-gel, a partir de mezclas de alquilalcoxisilanos Si(CH3(OCH2CH33 (MTEOS–SiH(CH3(OCH2CH32 (MDES, sistema A, y SiH(CH3(OCH2CH32 (MDES–SiH(OCH2CH33 (TREOS, sistema B, en presencia de n-propóxido de circonio. Se efectúa una variación del sistema A por adición de acetilacetona, sistema A-acac. Las matrices se caracterizan por espectroscopia infrarroja, resonancia magnética nuclear (RMN-MAS y análisis químico. Se estudian las características ópticas de los materiales obtenidos. Las matrices A-acac y B se dopan con una sal de Eu(III y las matrices A y B con una sal de Ce(IV. Los estudios de absorción y emisión indican la presencia de Eu(II y Ce(III, es decir estos estados de oxidación se han generado in situ a temperatura ambiente en los

  17. Duplication and Loss of Function of Genes Encoding RNA Polymerase III Subunit C4 Causes Hybrid Incompatibility in Rice

    Directory of Open Access Journals (Sweden)

    Giao Ngoc Nguyen

    2017-08-01

    Full Text Available Reproductive barriers are commonly observed in both animals and plants, in which they maintain species integrity and contribute to speciation. This report shows that a combination of loss-of-function alleles at two duplicated loci, DUPLICATED GAMETOPHYTIC STERILITY 1 (DGS1 on chromosome 4 and DGS2 on chromosome 7, causes pollen sterility in hybrid progeny derived from an interspecific cross between cultivated rice, Oryza sativa, and an Asian annual wild rice, O. nivara. Male gametes carrying the DGS1 allele from O. nivara (DGS1-nivaras and the DGS2 allele from O. sativa (DGS2-T65s were sterile, but female gametes carrying the same genotype were fertile. We isolated the causal gene, which encodes a protein homologous to DNA-dependent RNA polymerase (RNAP III subunit C4 (RPC4. RPC4 facilitates the transcription of 5S rRNAs and tRNAs. The loss-of-function alleles at DGS1-nivaras and DGS2-T65s were caused by weak or nonexpression of RPC4 and an absence of RPC4, respectively. Phylogenetic analysis demonstrated that gene duplication of RPC4 at DGS1 and DGS2 was a recent event that occurred after divergence of the ancestral population of Oryza from other Poaceae or during diversification of AA-genome species.

  18. Electrochemical Sensing toward Trace As(III) Based on Mesoporous MnFe₂O₄/Au Hybrid Nanospheres Modified Glass Carbon Electrode.

    Science.gov (United States)

    Zhou, Shaofeng; Han, Xiaojuan; Fan, Honglei; Liu, Yaqing

    2016-06-22

    Au nanoparticles decorated mesoporous MnFe₂O₄ nanocrystal clusters (MnFe₂O₄/Au hybrid nanospheres) were used for the electrochemical sensing of As(III) by square wave anodic stripping voltammetry (SWASV). Modified on a cheap glass carbon electrode, these MnFe₂O₄/Au hybrid nanospheres show favorable sensitivity (0.315 μA/ppb) and limit of detection (LOD) (3.37 ppb) toward As(III) under the optimized conditions in 0.1 M NaAc-HAc (pH 5.0) by depositing for 150 s at the deposition potential of -0.9 V. No obvious interference from Cd(II) and Hg(II) was recognized during the detection of As(III). Additionally, the developed electrode displayed good reproducibility, stability, and repeatability, and offered potential practical applicability for electrochemical detection of As(III) in real water samples. The present work provides a potential method for the design of new and cheap sensors in the application of electrochemical determination toward trace As(III) and other toxic metal ions.

  19. Electrochemical Sensing toward Trace As(III Based on Mesoporous MnFe2O4/Au Hybrid Nanospheres Modified Glass Carbon Electrode

    Directory of Open Access Journals (Sweden)

    Shaofeng Zhou

    2016-06-01

    Full Text Available Au nanoparticles decorated mesoporous MnFe2O4 nanocrystal clusters (MnFe2O4/Au hybrid nanospheres were used for the electrochemical sensing of As(III by square wave anodic stripping voltammetry (SWASV. Modified on a cheap glass carbon electrode, these MnFe2O4/Au hybrid nanospheres show favorable sensitivity (0.315 μA/ppb and limit of detection (LOD (3.37 ppb toward As(III under the optimized conditions in 0.1 M NaAc-HAc (pH 5.0 by depositing for 150 s at the deposition potential of −0.9 V. No obvious interference from Cd(II and Hg(II was recognized during the detection of As(III. Additionally, the developed electrode displayed good reproducibility, stability, and repeatability, and offered potential practical applicability for electrochemical detection of As(III in real water samples. The present work provides a potential method for the design of new and cheap sensors in the application of electrochemical determination toward trace As(III and other toxic metal ions.

  20. The Hybrid Hyrax Distalizer, a new all-in-one appliance for rapid palatal expansion, early class III treatment and upper molar distalization.

    Science.gov (United States)

    Wilmes, Benedict; Ludwig, Björn; Katyal, Vandana; Nienkemper, Manuel; Rein, Anna; Drescher, Dieter

    2014-09-01

    Growing class III patients with maxillary deficiency may be treated with a maxillary protraction facemask. Because the force generated by this appliance is applied to the teeth, the inevitable mesial migration of the dentition can result in anterior crowding, incisor proclination and a possible need for subsequent extraction therapy. The Hybrid Hyrax appliance, anchored on mini-implants in the anterior palate, can be used to overcome these side-effects during the facemask therapy. In some class III cases, there is also a need for subsequent distalization after the orthopaedic treatment. In this paper, clinical application of the Hybrid Hyrax Distalizer is described, facilitating both orthopaedic advancement of the maxilla and simultaneous orthodontic distalization of the maxillary molars.

  1. Functional outcome after Mason II-III radial head and neck fractures: study protocol for a systematic review in accordance with the PRISMA statement.

    Science.gov (United States)

    Hagelberg, Mårten; Thune, Alexandra; Krupic, Ferid; Salomonsson, Björn; Sköldenberg, Olof

    2017-01-27

    Fractures of the radial head and neck are the most common fractures of the elbow, and account for approximately one-third of all elbow fractures. Depending on the fracture type the treatment is either conservative or surgical. There is no absolute consensus regarding optimal treatment for different fracture types. The aim of this protocol is to present the method that will be used to collect, describe and analyse the current evidence regarding the treatment of Mason II-III radial head and neck fractures. We will conduct a systematic review in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P) guidelines statement. We will search a number of databases with a predefined search strategy to collect both randomised and non-randomised studies. The articles will be summarised with descriptive statistics. If applicable a meta-analysis will be conducted. Ethical approval is not required since this is a protocol for a systematic review and no primary data will be collected. The authors will publish findings from this review in a peer-reviewed scientific journal. CRD42016037627. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  2. Cisplatin, hyperthermia, and radiation (trimodal therapy) in patients with locally advanced head and neck tumors: A phase I-II study

    Energy Technology Data Exchange (ETDEWEB)

    Amichetti, M.; Graiff, C.; Fellin, G.; Pani, G.; Bolner, A.; Maluta, S. (Divisione di Radioterapia Oncologica, Trento (Italy)); Valdagni, R. (Divisione di Radioterapia Oncologica, Trento (Italy) Istituto per la Ricerca Scientifica e Tecnologica, Trento (Italy))

    1993-08-01

    Hyperthermia is now being widely used to treat clinical malignancies, especially combined with radiotherapy and more rarely with chemotherapy. The combination of heat, radiation, and chemotherapy (trimodality) can lead to potent interaction. The present Phase I-II study was conducted to evaluate the feasibility and acute toxicity of a combination of cisplantin, hyperthermia, and irradiation in the treatment of superficial cervical nodal metastases from head and neck cancer. Eighteen patients with measurable neck metastases from previously untreated squamous cell head and neck tumors were entered into the trial. Therapy consisted of a conventional irradiation (total dose 70 Gy, 2 Gy five times a week) combined with a weekly administration of 20 mg/m[sup 2] iv of cisplatin and a total of two sessions of local external microwave hyperthermia (desired temperature of 42.5[degrees]C for 30 min). Feasibility of the treatment was demonstrated. Acute local toxicity was mild; no thermal blisters or ulcerations were reported and only two patients experienced local pain during hyperthermia. Cutaneous toxicity appeared greater than in previous studies with irradiation plus hyperthermia and irradiation plus cisplatin. Systematic toxicity was moderate with major toxic effects observed in three patients (World Health Organization (WHO) grade 3 anaemia). Even though it was not an aim of the study to evaluate the nodal response, they observed a complete response rate of 72.2% (95% confidence interval 51-93.4%), 16.6% of partial response and 11.1% of no change. The study confirms the feasibility of the combination of cisplantin, heat, and radiation with an acceptable toxicity profile. The trimodal therapy deserves further evaluation as a way to enhance the efficacy of irradiation in the treatment of nodal metastases from head and neck tumors. 43 refs., 3 figs., 4 tabs.

  3. Concurrent radiotherapy and chemotherapy with carboplatin in patients with unresectable advanced head and neck tumors stages III and IV; Simultane Radiochemotherapie mit Carboplatin bei Patienten mit inoperablen fortgeschrittenen Kopf-Hals-Tumoren der Stadien UICC III und IV

    Energy Technology Data Exchange (ETDEWEB)

    Muecke, R.; Ziegler, P.G.; Libera, T.; Fietkau, R. [Rostock Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie; Blynow, M.; Dommerich, S.; Kramp, B. [Rostock Univ. (Germany). HNO-Klinik und Poliklinik; Kundt, G. [Rostock Univ. (Germany). Inst. fuer Medizinische Informatik und Biometrie

    1999-05-01

    Background: The results of treating advanced tumors in the head and neck region with radiotherapy alone are disappointing. Concurrent radiotherapy and chemotherapy may improve this situation. The treatment results of concurrent radiochemotherapy at the University of Rostock were analyzed retrospectively. Results: Six weeks after radiochemotherapy 56.5% of patients had a complete remission, 36% a partial remission and 7.5% `no change`. With a median follow-up of 42 months (6 to 74 months) overall survival, disease-free survival and local control were 24.3%, 28.9%, 18.0% 5 years after treatment. All these criteria were significantly better in patients with palliative tumor resection compared to no surgical treatment (uni- and multivariate) and in patients with Stage III than in patients with Stage IV carcinomas (univariate), overall survival was significantly better in patients with Stage III (multivariate). A pretherapeutic Hb level below 7.0 mmol/l (11.27 g/dl) reduced the local control significantly (uni- and multivariate). Grade III and IV mucositis was detected in 10%, Grade III leucopenia in 12% of treated patients. Grade IV leucopenia and Grade III thrombopenia were observed in 1 patient each. Conclusion: The toxicity of this treatment is tolerable. However, additional trials must be conducted before considering the palliative tumor resection as standard therapy. (orig./AJ) [Deutsch] Hintergrund: Die Therapieergebnisse der Behandlung fortgeschrittener Tumoren der Kopf-Hals-Region mit alleiniger Bestrahlung sind unbefriedigend. Eine simultane Radiochemotherapie verbessert diese Resultate vermutlich. In einer retrospektiven Analyse wurden Ergebnisse nach simultaner Radiochemotherapie an der Universitaet Rostock ausgewertet. Ergebnisse: Sechs Wochen nach Radiochemotherapie erreichten 56,5% der Patienten eine komplette und 36% der Patienten eine partielle Remission, ein `no change` war bei 7,5% der Patienten festzustellen. Bei einer medianen Beobachtungszeit von

  4. Ethanol mediated As(III) adsorption onto Zn-loaded pinecone biochar: Experimental investigation, modeling, and optimization using hybrid artificial neural network-genetic algorithm approach.

    Science.gov (United States)

    Zafar, Mohd; Van Vinh, N; Behera, Shishir Kumar; Park, Hung-Suck

    2017-04-01

    Organic matters (OMs) and their oxidization products often influence the fate and transport of heavy metals in the subsurface aqueous systems through interaction with the mineral surfaces. This study investigates the ethanol (EtOH)-mediated As(III) adsorption onto Zn-loaded pinecone (PC) biochar through batch experiments conducted under Box-Behnken design. The effect of EtOH on As(III) adsorption mechanism was quantitatively elucidated by fitting the experimental data using artificial neural network and quadratic modeling approaches. The quadratic model could describe the limiting nature of EtOH and pH on As(III) adsorption, whereas neural network revealed the stronger influence of EtOH (64.5%) followed by pH (20.75%) and As(III) concentration (14.75%) on the adsorption phenomena. Besides, the interaction among process variables indicated that EtOH enhances As(III) adsorption over a pH range of 2 to 7, possibly due to facilitation of ligand-metal(Zn) binding complexation mechanism. Eventually, hybrid response surface model-genetic algorithm (RSM-GA) approach predicted a better optimal solution than RSM, i.e., the adsorptive removal of As(III) (10.47μg/g) is facilitated at 30.22mg C/L of EtOH with initial As(III) concentration of 196.77μg/L at pH5.8. The implication of this investigation might help in understanding the application of biochar for removal of various As(III) species in the presence of OM. Copyright © 2016. Published by Elsevier B.V.

  5. Randomized phase III trial of postoperative radiochemotherapy {+-} amifostine in head and neck cancer. Is there evidence for radioprotection?

    Energy Technology Data Exchange (ETDEWEB)

    Vacha, P.; Fehlauer, F.; Mahlmann, B.; Marx, M.; Richter, E. [Dept. of Radiation Oncology and Nuclear Medicine, Univ. of Luebeck (Germany); Hinke, A. [WiSP Research Inst., Langenfeld (Germany); Sommer, K. [Dept. of Head and Neck Surgery, Univ. of Luebeck (Germany); Feyerabend, T. [Practice for Radiation Therapy Bonn-Rhein-Sieg, Bonn (Germany)

    2003-06-01

    Purpose: Experimental and clincial data suggest a reduction of radiation-induced acute toxicity by amifostine (A). We investigated this issue in a randomized trial comparing radiochemotherapy (RT + CT) versus radiochemotherapy plus amifostine (RC + CT + A) in patients with head and neck cancer. Patients and Methods: 56 patients with oro-/hypopharynx or larynx cancer (T1-2 N1-2 G3, T3-4 N0-2 G1-3) were randomized to received RC + CT alone or RC + CT + A. Patients were irradiated up to 60 Gy (R0) or 70 Gy (R1/2) and received chemotherapy (70 mg/m{sup 2} carboplatin, day 1-5 week 1 and 5 of radiotherapy). 250 mg amifostine were applied daily before each radiotherapy session. Acute toxicity was evaluated according to the common toxicity criteria (CTC). As for acute xerostomia, patients with laryngeal cancer were excluded from evaluation. Results: 50 patients were evaluable (25 patients in the RC + CT, 25 patients in the RC + CT + A group). Clinical characteristics were well balanced in both treatment groups. Amifostine provided reduction in acute xerostomia and mucositis but had no obvious influence on Karnofsky performance status, body weight, cutaneous side effects, and alopecia. The differences between both groups were statistically significant for acute xerostomia and nonsignificant, but with a trend for mucositis. Conclusions: According to our results, there is a radioprotective effect on salivary glands and a potential effect on oral mucosa by amifostine in postoperative radiotherapy combined with carboplatin. To improve the radio- and chemoprotective effects of amifostine in clinical practice, the application of a higher dose (> 250 mg) seems to be necessary. (orig.)

  6. Assessing fidelity of cognitive behavioral therapy in rural VA clinics: design of a randomized implementation effectiveness (hybrid type III) trial.

    Science.gov (United States)

    Cucciare, Michael A; Curran, Geoffrey M; Craske, Michelle G; Abraham, Traci; McCarthur, Michael B; Marchant-Miros, Kathy; Lindsay, Jan A; Kauth, Michael R; Landes, Sara J; Sullivan, Greer

    2016-05-10

    Broadly disseminating and implementing evidence-based psychotherapies with high fidelity, particularly cognitive behavioral therapy (CBT), has proved challenging for many health-care systems, including the Department of Veterans Affairs, especially in primary care settings such as small or remote clinics. A computer-based tool (based on the coordinated anxiety learning and management (CALM) program) was designed to support primary care-based mental health providers in delivering CBT. The objectives of this study are to modify the CALM tool to meet the needs of mental health clinicians in veterans affairs (VA) community-based outpatient clinics (CBOCs) and rural "veterans", use external facilitation to implement CBT and determine the effect of the CALM tool versus a manualized version of CALM to improve fidelity to the CBT treatment model, and conduct a needs assessment to understand how best to support future implementation of the CALM tool in routine care. Focus groups will inform the redesign of the CALM tool. Mental health providers at regional VA CBOCs; CBT experts; VA experts in implementation of evidence-based mental health practices; and veterans with generalized anxiety disorder, panic disorder, social anxiety disorder, posttraumatic stress disorder, "with or without" depression will be recruited. A hybrid type III design will be used to examine the effect of receiving CBT training plus either the CALM tool or a manual version of CALM on treatment fidelity. External facilitation will be used as the overarching strategy to implement both CBT delivery methods. Data will also be collected on symptoms of the targeted disorders. To help prepare for the future implementation of the CALM tool in VA CBOCs, we will perform an implementation need assessment with mental health providers participating in the clinical trial and their CBOC directors. This project will help inform strategies for delivering CBT with high fidelity in VA CBOCs to veterans with anxiety

  7. DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion

    Science.gov (United States)

    Schwarz, Friedrich W.; van Aelst, Kara; Tóth, Júlia; Seidel, Ralf; Szczelkun, Mark D.

    2011-01-01

    DNA cleavage by the Type III Restriction–Modification enzymes requires communication in 1D between two distant indirectly-repeated recognitions sites, yet results in non-specific dsDNA cleavage close to only one of the two sites. To test a recently proposed ATP-triggered DNA sliding model, we addressed why one site is selected over another during cleavage. We examined the relative cleavage of a pair of identical sites on DNA substrates with different distances to a free or protein blocked end, and on a DNA substrate using different relative concentrations of protein. Under these conditions a bias can be induced in the cleavage of one site over the other. Monte-Carlo simulations based on the sliding model reproduce the experimentally observed behaviour. This suggests that cleavage site selection simply reflects the dynamics of the preceding stochastic enzyme events that are consistent with bidirectional motion in 1D and DNA cleavage following head-on protein collision. PMID:21724613

  8. Acetylene bridged porphyrin-monophthalocyaninato ytterbium(III) hybrids with strong two-photon absorption and high singlet oxygen quantum yield.

    Science.gov (United States)

    Ke, Hanzhong; Li, Wenbin; Zhang, Tao; Zhu, Xunjin; Tam, Hoi-Lam; Hou, Anxin; Kwong, Daniel W J; Wong, Wai-Kwok

    2012-04-21

    Several acetylene bridged porphyrin-monophthalocyaninato ytterbium(III) hybrids, PZn-PcYb, PH(2)-PcYb and PPd-PcYb, have been prepared and characterized by (1)H and (31)P NMR, mass spectrometry, and UV-vis spectroscopy. Their photophysical and photochemical properties, especially the relative singlet oxygen ((1)O(2)) quantum yields and the two-photon absorption cross-section (σ(2)), were investigated. These three newly synthesized compounds exhibited very large σ(2) values and substantial (1)O(2) quantum yields upon photo-excitation, making them potential candidates as one- and two-photon photodynamic therapeutic agents.

  9. Morphometric Optic Nerve Head Analysis in Glaucoma Patients: A Comparison between the Simultaneous Nonmydriatic Stereoscopic Fundus Camera (Kowa Nonmyd WX3D and the Heidelberg Scanning Laser Ophthalmoscope (HRT III

    Directory of Open Access Journals (Sweden)

    Siegfried Mariacher

    2016-01-01

    Full Text Available Purpose. To investigate the agreement between morphometric optic nerve head parameters assessed with the confocal laser ophthalmoscope HRT III and the stereoscopic fundus camera Kowa nonmyd WX3D retrospectively. Methods. Morphometric optic nerve head parameters of 40 eyes of 40 patients with primary open angle glaucoma were analyzed regarding their vertical cup-to-disc-ratio (CDR. Vertical CDR, disc area, cup volume, rim volume, and maximum cup depth were assessed with both devices by one examiner. Mean bias and limits of agreement (95% CI were obtained using scatter plots and Bland-Altman analysis. Results. Overall vertical CDR comparison between HRT III and Kowa nonmyd WX3D measurements showed a mean difference (limits of agreement of −0.06 (−0.36 to 0.24. For the CDR < 0.5 group (n=24 mean difference in vertical CDR was −0.14 (−0.34 to 0.06 and for the CDR ≥ 0.5 group (n=16 0.06 (−0.21 to 0.34. Conclusion. This study showed a good agreement between Kowa nonmyd WX3D and HRT III with regard to widely used optic nerve head parameters in patients with glaucomatous optic neuropathy. However, data from Kowa nonmyd WX3D exhibited the tendency to measure larger CDR values than HRT III in the group with CDR < 0.5 group and lower CDR values in the group with CDR ≥ 0.5.

  10. Plant Type and Its Effects on Canopy Structure at Heading Stage in Various Ecological Areas for a Two-line Hybrid Rice Combination, Liangyoupeijiu

    Institute of Scientific and Technical Information of China (English)

    LU Chuan-gen; HU Ning; YAO Ke-min; XIA Shi-jian; QI Qing-ming

    2010-01-01

    A two-line hybrid rice combination, Liangyoupeijiu, was used to estimate several factors of plant type, and environmental models for these factors at the heading stage were established using the data of eight ecological experimental sites in 2006 and 2007. According to climatic data from 1951 to 2005, the differences in those factors and their effects on plant canopy were analyzed for four rice cropping areas in China, including South China, the middle-lower reaches of the Yangtze River, Sichuan Basin, and river valley in Yunnan, China. The thickness of leaf layer (the distance from pulvinus of the third leaf from the top to the tip of flag leaf) and distribution of leaf area could be used as candidate indices for the plant type of a rice canopy.

  11. Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III

    DEFF Research Database (Denmark)

    Singer, Susanne; Araújo, Cláudia; Arraras, Juan Ignacio;

    2015-01-01

    BACKGROUND: The objective of this study was to pilot test an updated version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC QLQ-H&N60). METHODS: Patients with head and neck cancer were asked to complete a list of 60 head...

  12. Oral Mucositis Prevention By Low-Level Laser Therapy in Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy: A Phase III Randomized Study

    Energy Technology Data Exchange (ETDEWEB)

    Gouvea de Lima, Aline [Departamento de Radiologia, Disciplina de Oncologia, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP (Brazil); Villar, Rosangela Correa [Instituto de Radiologia, Servico de Radioterapia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP (Brazil); Castro, Gilberto de, E-mail: gilberto.castro@usp.br [Department of Clinical Oncology, Instituto do Cancer do Estado de Sao Paulo, Sao Paulo, SP (Brazil); Antequera, Reynaldo [Divisao de Odontologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP (Brazil); Gil, Erlon; Rosalmeida, Mauro Cabral [Instituto de Radiologia, Servico de Radioterapia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP (Brazil); Federico, Miriam Hatsue Honda; Snitcovsky, Igor Moises Longo [Departamento de Radiologia, Disciplina de Oncologia, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP (Brazil)

    2012-01-01

    Purpose: Oral mucositis is a major complication of concurrent chemoradiotherapy (CRT) in head-and-neck cancer patients. Low-level laser (LLL) therapy is a promising preventive therapy. We aimed to evaluate the efficacy of LLL therapy to decrease severe oral mucositis and its effect on RT interruptions. Methods and Materials: In the present randomized, double-blind, Phase III study, patients received either gallium-aluminum-arsenide LLL therapy 2.5 J/cm{sup 2} or placebo laser, before each radiation fraction. Eligible patients had to have been diagnosed with squamous cell carcinoma or undifferentiated carcinoma of the oral cavity, pharynx, larynx, or metastases to the neck with an unknown primary site. They were treated with adjuvant or definitive CRT, consisting of conventional RT 60-70 Gy (range, 1.8-2.0 Gy/d, 5 times/wk) and concurrent cisplatin. The primary endpoints were the oral mucositis severity in Weeks 2, 4, and 6 and the number of RT interruptions because of mucositis. The secondary endpoints included patient-reported pain scores. To detect a decrease in the incidence of Grade 3 or 4 oral mucositis from 80% to 50%, we planned to enroll 74 patients. Results: A total of 75 patients were included, and 37 patients received preventive LLL therapy. The mean delivered radiation dose was greater in the patients treated with LLL (69.4 vs. 67.9 Gy, p = .03). During CRT, the number of patients diagnosed with Grade 3 or 4 oral mucositis treated with LLL vs. placebo was 4 vs. 5 (Week 2, p = 1.0), 4 vs. 12 (Week 4, p = .08), and 8 vs. 9 (Week 6, p = 1.0), respectively. More of the patients treated with placebo had RT interruptions because of mucositis (6 vs. 0, p = .02). No difference was detected between the treatment arms in the incidence of severe pain. Conclusions: LLL therapy was not effective in reducing severe oral mucositis, although a marginal benefit could not be excluded. It reduced RT interruptions in these head-and-neck cancer patients, which might

  13. Synthesis of an organic–inorganic hybrid material by solid state intercalation of 2-mercaptopyridine into Na-, Al(III)- and Co(II)-montmorillonite

    Indian Academy of Sciences (India)

    I Bekri-Abbes; E Srasra

    2006-06-01

    The preparation of an organic–inorganic hybrid material by solid state intercalation of 2-merca-ptopyridine (2Mpy) into Na-, Co(II)- and Al(III)-montmorillonite has been studied using a variety of techniques. The extension of 001 from XRD proves that the intercalation of 2-mercaptopyridine into Na-, Co(II)- and Al(III)-mont occurs at ambient temperature in 5 mn. When the intercalated samples were heated at different temperatures, we found that the 001 gave different values. For instance, for intercalated Al(III)- and Co(II)-, 001 remained unchanged for a temperature under 500°C. However, for intercalated Na-mont, it shifted to 14 Å for a temperature of 300°C, the washing of different samples with a methanol solution shifted the 001 of intercalated Na-mont to 14 Å. However, for intercalated Al(III) and Co(II), it did not change. This proves that in the case of Na-mont, the molecules of 2-mercaptopyridine interact with the clay through hydrogen bindings and physical interactions. However, for Al(III) and Co(II), it forms coordination linking and physical interaction. 13C NMR and FTIR spectroscopy have been employed for the characterization of the intercalation compounds. Tautomeric equilibrium between thiol and thione species of 2-mercaptopyridine must be taken into account to explain the arrangement of molecular aggregates and their particular orientation in the interlayer space. The isotherm of adsorption–desorption of nitrogen and topographic AFM images prove that intercalation of 2Mpy is accompanied by a total blockage of clay porosity and an increase in roughness.

  14. Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study.

    Science.gov (United States)

    Cohen, Ezra E W; Davis, Darren W; Karrison, Theodore G; Seiwert, Tanguy Y; Wong, Stuart J; Nattam, Sreenivasa; Kozloff, Mark F; Clark, Joseph I; Yan, Duen-Hwa; Liu, Wen; Pierce, Carolyn; Dancey, Janet E; Stenson, Kerstin; Blair, Elizabeth; Dekker, Allison; Vokes, Everett E

    2009-03-01

    Epidermal growth factor receptor (EGFR) is a validated target in squamous-cell carcinoma of the head and neck, but in patients with recurrent or metastatic disease, EGFR targeting agents have displayed modest efficacy. Vascular endothelial growth factor (VEGF)-mediated angiogenesis has been implicated as a mechanism of resistance to anti-EGFR therapy. In this multi-institutional phase I/II study we combined an EGFR inhibitor, erlotinib, with an anti-VEGF antibody, bevacizumab. Between April 15, 2003, and Jan 27, 2005, patients with recurrent or metastatic squamous-cell carcinoma of the head and neck were enrolled from seven centres in the USA and were given erlotinib (150 mg daily) and bevacizumab in escalating dose cohorts. The primary objectives in the phase I and II sections, respectively, were to establish the maximum tolerated dose and dose-limiting toxicity of bevacizumab when administered with erlotinib and to establish the proportion of objective responses and time to disease progression. Pretreatment serum and tissues were collected and analysed by enzyme-linked immunosorbent assay and immunofluorescence quantitative laser analysis, respectively. This study was registered with ClinicalTrials.gov, number NCT00055913. In the phase I section of the trial, ten patients were enrolled in three successive cohorts with no dose-limiting toxic effects noted. 46 patients were enrolled in the phase II section of the trial (including three patients from the phase I section) on the highest dose of bevacizumab (15 mg/kg every 3 weeks). Two additional patients were accrued beyond the protocol-stipulated 46, leaving a total of 48 patients for the phase II assessment. The most common toxic effects of any grade were rash and diarrhoea (41 and 16 of 48 patients, respectively). Three patients had serious bleeding events of grade 3 or higher. Seven patients had a response, with four showing a complete response allowing rejection of the null hypothesis. Median time of overall

  15. Eu(III) local coordination in white light emitters organic-inorganic hybrids; Coordenacao local do Eu(III) em hibridos organicos-inorganicos emissores de luz branca

    Energy Technology Data Exchange (ETDEWEB)

    Carlos, Luis D.; Ferreira, Rute A. Sa [Universidade de Aveiro (Portugal). Dept. de Fisica]. E-mail: lcarlos@ideiafix.fis.ua.pt; Bermudez, Veronica Zea de [Universidade de Tras-os-Montes e Alto Douro, Quinta de Prados (Portugal). Dept. de Quimica; Bueno, Luciano A.; Molina, Celso; Messaddeq, Younes; Ribeiro, Sidney J.L. [UNESP, Araraquara, SP (Brazil). Inst. de Quimica]. E-mail: sidney@iq.unesp.br

    2001-08-01

    Eu{sup 3+} luminescence and EXAFS (Extended X-Ray Absorption Fine Structure) results are presented for organic-inorganic hybrid gel hosts composed of a siliceous network to which small chains of oxy ethylene units are covalently grafted by means of urea bridges. Coordination numbers for Eu {sup 3+} ions range from 12.8 to 9.7 with increasing Eu {sup 3+} concentration while the Eu {sup 3=}-first neighbours mean distance is found to be constant at 2.48-2.49 angstrom in the same concentration range. Emission spectra display a broad band in the green/blue spectral region superposed to narrow lines appearing in the yellow/red region in such a way that for the eyes emission appears white. The broad band is assigned to intrinsic N H groups emission and also to electron-hole recombination in the nanosized siliceous domains. The narrow lines are assigned to intra-4f{sup 6}, {sup 5} D{sub 0}{yields}{sup 7} F{sub 0-4} Eu {sup 3+} transitions and from the energy position of the {sup 7} F{sub 0-4} levels a mean distance could be calculated for the Eu {sup 3+}-first neighbours. The calculated results are in good agreement with the experimental ones obtained from EXAFS analysis. (author)

  16. Hybrid III-V on Si grating as a broadband reflector and a high-Q resonator

    DEFF Research Database (Denmark)

    Chung, Il-Sug; Taghizadeh, Alireza; Park, Gyeong Cheol

    2016-01-01

    Hybrid grating (HG) with a high-refractive-index cap layer added onto a high contrast grating (HCG), can provide a high reflectance close 100 % over a broader wavelength range than HCGs, or work as a ultrahigh quality (Q) factor resonator. The reflection and resonance properties of HGs have been...

  17. First Kepler results on compact pulsators - III. Subdwarf B stars with V1093 Her and hybrid (DW Lyn) type pulsations

    DEFF Research Database (Denmark)

    Reed, M.D.; Kawaler, Stephen D.; Østensen, Roy H.

    2010-01-01

    1093 Her (PG 1716) class or a hybrid star with both short and long periods. The apparently non-binary long-period and hybrid pulsators are described here. The V1093 Her periods range from 1 to 4.5 h and are associated with g-mode pulsations. Three stars also exhibit short periods indicative of p......We present the discovery of non-radial pulsations in five hot subdwarf B (sdB) stars based on 27 d of nearly continuous time series photometry using the Kepler spacecraft. We find that every sdB star cooler than ≈27 500 K that Kepler has observed (seven so far) is a long-period pulsator of the V......-modes with periods of 2-5 min and in addition, these stars exhibit periodicities between both classes from 15 to 45 min. We detect the coolest and longest-period V1093 Her-type pulsator to date, KIC010670103 (Teff≈ 20 900 K, Pmax≈ 4.5 h) as well as a suspected hybrid pulsator, KIC002697388, which is extremely cool...

  18. Phase 2 Study of Docetaxel, Cisplatin, and Concurrent Radiation for Technically Resectable Stage III-IV Squamous Cell Carcinoma of the Head and Neck

    Energy Technology Data Exchange (ETDEWEB)

    Inohara, Hidenori, E-mail: hinohara@ent.med.osaka-u.ac.jp [Department of Otorhinolaryngology—Head and Neck Surgery, Osaka University Faculty of Medicine, Suita, Osaka (Japan); Takenaka, Yukinori; Yoshii, Tadashi; Nakahara, Susumu; Yamamoto, Yoshifumi; Tomiyama, Yoichiro [Department of Otorhinolaryngology—Head and Neck Surgery, Osaka University Faculty of Medicine, Suita, Osaka (Japan); Seo, Yuji; Isohashi, Fumiaki; Suzuki, Osamu; Yoshioka, Yasuo; Sumida, Iori; Ogawa, Kazuhiko [Department of Radiation Oncology, Osaka University Faculty of Medicine, Suita, Osaka (Japan)

    2015-04-01

    Purpose: We investigated the efficacy and safety of weekly low-dose docetaxel and cisplatin therapy concurrent with conventionally fractionated radiation in patients with technically resectable stage III-IV squamous cell carcinoma of the head and neck. Methods and Materials: Between March 2004 and October 2011, we enrolled 117 patients, of whom 116 were analyzable (43 had oropharyngeal cancer, 54 had hypopharyngeal cancer, and 19 had laryngeal cancer), and 85 (73%) had stage IV disease. Radiation consisted of 66 Gy in 33 fractions. Docetaxel, 10 mg/m{sup 2}, followed by cisplatin, 20 mg/m{sup 2}, administered on the same day were given once a week for 6 cycles. The primary endpoint was overall complete response (CR) rate after chemoradiation therapy. Human papillomavirus (HPV) DNA in oropharyngeal cancer was examined by PCR. Results: Of 116 patients, 82 (71%) completed treatment per protocol; 102 (88%) received the full radiation therapy dose; and 90 (78%) and 12 (10%) patients received 6 and 5 chemotherapy cycles, respectively. Overall CR rate was 71%. After median follow-up of 50.9 months (range: 15.6-113.9 months for surviving patients), 2-year and 4-year overall survival rates were 82% and 68%, respectively. Cumulative 2-year and 4-year local failure rates were 27% and 28%, respectively, whereas distant metastasis rates were 15% and 22%, respectively. HPV status in oropharyngeal cancer was not associated with treatment efficacy. Acute toxicity included grade 3 and 4 in-field mucositis in 73% and 5% of patients, respectively, whereas myelosuppression and renal injury were minimal. No patients died of toxicity. Feeding tube dependence in 8% and tracheostomy in 1% of patients were evident at 2 years postchemoradiation therapy in patients who survived without local treatment failure. Conclusions: Local control and survival with this regimen were satisfactory. Although acute toxicity, such as mucositis, was common, late toxicity, such as laryngoesophageal

  19. Characterization of cellulose I/II hybrid fibers isolated from energycane bagasse during the delignification process: Morphology, crystallinity and percentage estimation.

    Science.gov (United States)

    Yue, Yiying; Han, Jingquan; Han, Guangping; Zhang, Quanguo; French, Alfred D; Wu, Qinglin

    2015-11-20

    Cellulose I, cellulose II and cellulose I/II hybrid fibers were prepared from energycane bagasse using NaOH and NaClO2 treatments. The definitive defibrillation effect with an average width of 12±5μm was observed for the fibers treated with 20wt% NaOH for 10h and NaClO2 for 2h. The ribbon shaped cellulose I fibers were converted to a swollen state with a rougher surface by 20wt% NaOH treatment for 10h. The percentage of cellulose I decreased from 100% to 5%, and the corresponding CI values increased from 58.2% to 68.8% during the conversion from cellulose I to II. After further NaClO2 treatment, the CI values were decreased because of partial destruction of hydrogen bond network. XRD, NMR and FTIR results present the same trend in the degree of crystallization for all the samples.

  20. Radiation Therapy With Cisplatin, Docetaxel, or Cetuximab After Surgery in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer

    Science.gov (United States)

    2017-05-18

    Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Tongue Cancer

  1. Co-integrated 1.3µm hybrid III-V/silicon tunable laser and silicon Mach-Zehnder modulator operating at 25Gb/s.

    Science.gov (United States)

    Ferrotti, Thomas; Blampey, Benjamin; Jany, Christophe; Duprez, Hélène; Chantre, Alain; Boeuf, Frédéric; Seassal, Christian; Ben Bakir, Badhise

    2016-12-26

    In this paper, the 200mm silicon-on-insulator (SOI) platform is used to demonstrate the monolithic co-integration of hybrid III-V/silicon distributed Bragg reflector (DBR) tunable lasers and silicon Mach-Zehnder modulators (MZMs), to achieve fully integrated hybrid transmitters for silicon photonics. The design of each active component, as well as the fabrication process steps of the whole architecture are described in detail. A data transmission rate up to 25Gb/s has been reached for transmitters using MZMs with active lengths of 2mm and 4mm. Extinction ratios of respectively 2.9dB and 4.7dB are obtained by applying drive voltages of 2.5V peak-to-peak on the MZMs. 25Gb/s data transmission is demonstrated at 1303.5nm and 1315.8nm, with the possibility to tune the operating wavelength by up to 8.5nm in each case, by using metallic heaters above the laser Bragg reflectors.

  2. Monolithic integration of hybrid III-V/Si lasers and Si-based modulators for data transmission up to 25Gbps

    Science.gov (United States)

    Ferrotti, Thomas; Blampey, Benjamin; Jany, Christophe; Duprez, Hélène; Chantre, Alain; Boeuf, Frédéric; Seassal, Christian; Ben Bakir, Badhise

    2017-02-01

    In this paper, the 200mm silicon-on-insulator (SOI) platform is used to demonstrate the monolithic co-integration of hybrid III-V/silicon Distributed Bragg Reflector (DBR) tunable lasers and silicon Mach-Zehnder modulator (MZMs), to achieve fully integrated hybrid transmitters for silicon photonics. The design of each active component, as well as the fabrication process steps of the whole architecture are described in details. Data transmission rate up to 25Gb/s has been reached for transmitters using MZMs with active lengths of 2mm and 4mm. Extinction ratios of respectively 2.9dB and 4.7dB are obtained by applying drive voltages of 2.5V peak-to-peak on the MZMs. 25Gb/s data transmission is demonstrated at 1303.5nm and 1315.8nm, with the possibility to tune the operating wavelength by up to 8.5nm in each case, by using metallic heaters above the lasers Bragg reflectors.

  3. Systematic defect donor levels in III-V and II-VI semiconductors revealed by hybrid functional density-functional theory

    Science.gov (United States)

    Petretto, Guido; Bruneval, Fabien

    2015-12-01

    The identification of defect levels from photoluminescence spectroscopy is a useful but challenging task. Density-functional theory (DFT) is a highly valuable tool to this aim. However, the semilocal approximations of DFT that are affected by a band gap underestimation are not reliable to evaluate defect properties, such as charge transition levels. It is now established that hybrid functional approximations to DFT improve the defect description in semiconductors. Here we demonstrate that the use of hybrid functionals systematically stabilizes donor defect states in the lower part of the band gap for many defects, impurities or vacancies, in III-V and in II-VI semiconductors, even though these defects are usually considered as acceptors. These donor defect states are a very general feature and, to the best of our knowledge, have been overlooked in previous studies. The states we identify here may challenge the older assignments to photoluminescent peaks. Though appealing to screen quickly through the possible stable charge states of a defect, semilocal approximations should not be trusted for that purpose.

  4. Density Functional Theory Simulations of Semiconductors for Photovoltaic Applications: Hybrid Organic-Inorganic Perovskites and III/V Heterostructures

    Directory of Open Access Journals (Sweden)

    Jacky Even

    2014-01-01

    Full Text Available Potentialities of density functional theory (DFT based methodologies are explored for photovoltaic materials through the modeling of the structural and optoelectronic properties of semiconductor hybrid organic-inorganic perovskites and GaAs/GaP heterostructures. They show how the properties of these bulk materials, as well as atomistic relaxations, interfaces, and electronic band-lineups in small heterostructures, can be thoroughly investigated. Some limitations of available standard DFT codes are discussed. Recent improvements able to treat many-body effects or based on density-functional perturbation theory are also reviewed in the context of issues relevant to photovoltaic technologies.

  5. Measurement of the absolute optical properties and cerebral blood volume of the adult human head with hybrid differential and spatially resolved spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Leung, Terence S [Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT (United Kingdom); Tachtsidis, Ilias [Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT (United Kingdom); Smith, Martin [Department of Neuroanaesthesia and Neurocritical Care, The National Hospital for Neurology and Neurosurgery, London (United Kingdom); Delpy, David T [Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT (United Kingdom); Elwell, Clare E [Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT (United Kingdom)

    2006-02-07

    A hybrid differential and spatially resolved spectroscopy (SRS) technique has been developed to measure absolute absorption coefficient ({mu}{sub a}), reduced scattering coefficient ({mu}'{sub s}) and cerebral blood volume (CBV) in the adult human head. A spectrometer with both differential and SRS capabilities has been used to carry out measurements in 12 subjects. Two versions of the calculation have been considered using the hybrid technique, with one considering water as a chromophore as well as oxy- and deoxy-haemoglobin, and one ignoring water. The CBV has also been measured using a previously described technique based on changing the arterial saturation (SaO{sub 2}) measured separately by a pulse oximeter, resulting in mean {+-} SD CBV{sup a} (intra-individual coefficient of variation) = 2.22 {+-} 1.06 ml/100 g (29.9%). (The superscript on CBV indicates the different calculation basis.) Using the hybrid technique with water ignored, CBV{sup 0} = 3.18 {+-} 0.73 ml/100 g (10.0%), {mu}{sup 0}{sub a}(813 nm) = 0.010 {+-} 0.003 mm{sup -1} and {mu}'{sup 0}{sub s}(813 nm) = 1.19 {+-} 0.55 mm{sup -1} (data quoted at 813 nm). With water considered, CBV{sup w} = 3.05 {+-} 0.77 ml/100 g (10.5%), {mu}{sup w}{sub a}(813 nm) = 0.010 {+-} 0.003 mm{sup -1} and {mu}'{sup w}{sub s}(813 nm) = 1.28 {+-} 0.56 mm{sup -1}. The mean biases between CBV{sup 0}/CBV{sup w}, CBV{sup 0}/CBV{sup a} and CBV{sup w}/CBV{sup a} are 0.14 {+-} 0.09, 0.79 {+-} 1.22 and 0.65 {+-} 1.24 ml/100 g. The mean biases between {mu}{sup 0}{sub a}(813 nm)/{mu}{sup w}{sub a}(813 nm) and {mu}'{sup 0}{sub s}(813 nm)/{mu}'{sup w}{sub s}(813 nm) are (5.9 {+-} 10.0) x 10{sup -4} mm{sup -1} and -0.084 {+-} 0.266 mm{sup -1}, respectively. The method we describe extends the functionality of the current SRS instrumentation.

  6. “Direct modulation of a hybrid III-V/Si DFB laser with MRR filtering for 22.5-Gb/s error-free dispersion-uncompensated transmission over 2.5-km SSMF

    DEFF Research Database (Denmark)

    Cristofori, Valentina; Da Ros, Francesco; Ding, Yunhong;

    2016-01-01

    Error-free and penalty-free transmission over 2.5 km SSMF of a 22.5 Gb/s data signal from a directly modulated hybrid III-V/Si DFB laser is achieved by enhancing the dispersion tolerance using a silicon micro-ring resonator....

  7. In pursuit of vehicle landmine occupant protection: Evaluating the dynamic response characteristic of the military lower extremity leg (MiL-Lx) compared to the Hybrid III (HIII) lower leg

    CSIR Research Space (South Africa)

    Pandelani, T

    2010-09-01

    Full Text Available This study presents the results of a practical investigation into the robustness of the newly developed Military Extremity (MiL-Lx) lower leg, as compared to the Hybrid III (HIII) lower leg, with respect to repeatability and reproducibility under...

  8. “Direct modulation of a hybrid III-V/Si DFB laser with MRR filtering for 22.5-Gb/s error-free dispersion-uncompensated transmission over 2.5-km SSMF

    DEFF Research Database (Denmark)

    Cristofori, Valentina; Da Ros, Francesco; Ding, Yunhong

    2016-01-01

    Error-free and penalty-free transmission over 2.5 km SSMF of a 22.5 Gb/s data signal from a directly modulated hybrid III-V/Si DFB laser is achieved by enhancing the dispersion tolerance using a silicon micro-ring resonator....

  9. Validation of a wireless head acceleration measurement system for use in soccer play.

    Science.gov (United States)

    Hanlon, Erin; Bir, Cynthia

    2010-11-01

    Soccer heading has been studied previously with conflicting results. One major issue is the lack of knowledge regarding what actually occurs biomechanically during soccer heading impacts. The purpose of the current study is to validate a wireless head acceleration measurement system, head impact telemetry system (HITS) that can be used to collect head accelerations during soccer play. The HIT system was fitted to a Hybrid III (HIII) head form that was instrumented with a 3-2-2-2 accelerometer setup. Fifteen impact conditions were tested to simulate impacts commonly experienced during soccer play. Linear and angular acceleration were calculated for both systems and compared. Root mean square (RMS) error and cross correlations were also calculated and compared for both systems. Cross correlation values were very strong with r = .95 ± 0.02 for ball to head forehead impacts and r = .96 ± 0.02 for head to head forehead impacts. The systems showed a strong relationship when comparing RMS error, linear head acceleration, angular head acceleration, and the cross correlation values.

  10. Exoplanet Imaging with a Phase-induced Amplitude Apodization Coronagraph III. Hybrid Approach: Optical Design and Diffraction Analysis

    CERN Document Server

    Pluzhnik, E A; Galicher, R; Guyon, O; Martinache, F; Ridgway, S T; Woodruff, R A

    2005-01-01

    Properly apodized pupils can deliver point spread functions (PSFs) free of Airy rings, and are suitable for high dynamical range imaging of extrasolar terrestrial planets (ETPs). To reach this goal, classical pupil apodization (CPA) unfortunately requires most of the light gathered by the telescope to be absorbed, resulting in poor throughput and low angular resolution. Phase-induced amplitude apodization (PIAA) of the telescope pupil (Guyon 2003) combines the advantages of classical pupil apodization (particularly low sensitivity to low order aberrations) with full throughput, no loss of angular resolution and little chromaticity, which makes it, theoretically, an extremely attractive coronagraph for direct imaging of ETPs. The two most challenging aspects of this technique are (1) the difficulty to polish the required optics shapes and (2) diffraction propagation effects which, because of their chromaticity, can decrease the spectral bandwidth of the coronagraph. We show that a properly designed hybrid syst...

  11. Optimization of a carbon-based hybrid energy storage device with cerium (III) sulfate as redox electrolyte

    Science.gov (United States)

    Díaz, Patricia; González, Zoraida; Santamaría, Ricardo; Granda, Marcos; Menéndez, Rosa; Blanco, Clara

    2016-03-01

    The electrochemical performance of a carbon-based hybrid energy storage system, with Ce2(SO4)3/H2SO4 as inorganic redox electrolyte, was enhanced by optimizing several parameters of the device. A mass balance of the two electrodes forming the system together with the selection of a suitable activated carbon as negative electrode allowed the cell voltage to be increased up to 1.9 V. In addition, the use of a cation-exchange membrane significantly enhanced the electrochemical performance of the system by minimizing secondary reactions of cerium ions on the negative electrode. The optimized device reached energy and power density values up to ∼20 W h kg-1 and 524 W kg-1 respectively. Moreover, the system showed a good long-term electrochemical performance over 20,000 cycles.

  12. Concussion in professional football: comparison with boxing head impacts--part 10.

    Science.gov (United States)

    Viano, David C; Casson, Ira R; Pellman, Elliot J; Bir, Cynthia A; Zhang, Liying; Sherman, Donald C; Boitano, Marilyn A

    2005-12-01

    This study addresses impact biomechanics from boxing punches causing translational and rotational head acceleration. Olympic boxers threw four different punches at an instrumented Hybrid III dummy and responses were compared with laboratory-reconstructed NFL concussions. Eleven Olympic boxers weighing 51 to 130 kg (112-285 lb) delivered 78 blows to the head of the Hybrid III dummy, including hooks, uppercuts and straight punches to the forehead and jaw. Instrumentation included translational and rotational head acceleration and neck loads in the dummy. Biaxial acceleration was measured in the boxer's hand to determine punch force. High-speed video recorded each blow. Hybrid III head responses and finite element (FE) brain modeling were compared to similarly determined responses from reconstructed NFL concussions. The hook produced the highest change in hand velocity (11.0 +/- 3.4 m/s) and greatest punch force (4405 +/- 2318 N) with average neck load of 855 +/- 537 N. It caused head translational and rotational accelerations of 71.2 +/- 32.2 g and 9306 +/- 4485 r/s. These levels are consistent with those causing concussion in NFL impacts. However, the head injury criterion (HIC) for boxing punches was lower than for NFL concussions because of shorter duration acceleration. Boxers deliver punches with proportionately more rotational than translational acceleration than in football concussion. Boxing punches have a 65 mm effective radius from the head cg, which is almost double the 34 mm in football. A smaller radius in football prevents the helmets from sliding off each other in a tackle. Olympic boxers deliver punches with high impact velocity but lower HIC and translational acceleration than in football impacts because of a lower effective punch mass. They cause proportionately more rotational acceleration than in football. Modeling shows that the greatest strain is in the midbrain late in the exposure, after the primary impact acceleration in boxing and football.

  13. Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III.

    Science.gov (United States)

    Singer, Susanne; Araújo, Cláudia; Arraras, Juan Ignacio; Baumann, Ingo; Boehm, Andreas; Brokstad Herlofson, Bente; Castro Silva, Joaquim; Chie, Wei-Chu; Fisher, Sheila; Guntinas-Lichius, Orlando; Hammerlid, Eva; Irarrázaval, María Elisa; Jensen Hjermstad, Marianne; Jensen, Kenneth; Kiyota, Naomi; Licitra, Lisa; Nicolatou-Galitis, Ourania; Pinto, Monica; Santos, Marcos; Schmalz, Claudia; Sherman, Allen C; Tomaszewska, Iwona M; Verdonck de Leeuw, Irma; Yarom, Noam; Zotti, Paola; Hofmeister, Dirk

    2015-09-01

    The objective of this study was to pilot test an updated version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC QLQ-H&N60). Patients with head and neck cancer were asked to complete a list of 60 head and neck cancer-specific items comprising the updated EORTC head and neck module and the core questionnaire EORTC QLQ-C30. Debriefing interviews were conducted to identify any irrelevant items and confusing or upsetting wording. Interviews were performed with 330 patients from 17 countries, representing different head and neck cancer sites and treatments. Forty-one of the 60 items were retained according to the predefined EORTC criteria for module development, for another 2 items the wording was refined, and 17 items were removed. The preliminary EORTC QLQ-H&N43 can now be used in academic research. Psychometrics will be tested in a larger field study. © 2014 Wiley Periodicals, Inc.

  14. Adsorption behavior of phosphate on lanthanum(III)-coordinated diamino-functionalized 3D hybrid mesoporous silicates material

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Jianda [School of Environmental Science and Engineering, Shanghai Jiaotong University, 800, Dongchuan Road, Shanghai 200240 (China); Tianjin Hydraulic Research Institute, 60, Youyi Road, Tianjin 300000 (China); Shen Zhemin, E-mail: zmshen@sjtu.edu.cn [School of Environmental Science and Engineering, Shanghai Jiaotong University, 800, Dongchuan Road, Shanghai 200240 (China); Shan Wenpo [College of Chemistry and Environmental Science, Hebei University, Baoding 071002 (China); Mei Zhijian; Wang Wenhua [School of Environmental Science and Engineering, Shanghai Jiaotong University, 800, Dongchuan Road, Shanghai 200240 (China)

    2011-02-15

    An inorganic/organic hybrid adsorbent for phosphate adsorption was synthesized by introducing lanthanum (La) onto diamino modified MCM-41. The adsorbent was characterized by XRD, SEM, BET, TGA, and FTIR spectroscopy. A series of batch tests were conducted to investigate the influence of contact time, initial phosphate concentration, pH of the solution, and competitive ions on the phosphate adsorption capacity. The Langmuir and Freundlich models were used to simulate the sorption equilibrium, and the results indicated that the Langmuir model fitted the experiment data better than the Freundlich model. The maximum adsorption capacity calculated from the Langmuir model is 54.3 mg/g. For kinetic study, phosphate adsorption followed the pseudo-second-order equation well with a correlation coefficient greater than 0.99. Optimum pH value for the removal of phosphate was between 3.0 and 7.0. The presence of Cl{sup -} and NO{sub 3}{sup -} has neglectable influence on the phosphate adsorption. F{sup -}and SO{sub 4}{sup 2-} have negative effects on the adsorption of phosphate. Phosphate on the spent adsorbent can be almost released by 0.01 M NaOH solution in 12 min.

  15. Luminescent hybrid materials based on covalent attachment of Eu(III)-tris(bipyridinedicarboxylate) in the mesoporous silica host MCM-41.

    Science.gov (United States)

    Ilibi, Maturi; de Queiroz, Thiago Branquinho; Ren, Jinjun; De Cola, Luisa; de Camargo, Andrea Simone Stucchi; Eckert, Hellmut

    2014-06-14

    A luminescent inorganic-organic hybrid material was synthesized by covalent immobilization of a europium bipyridine carboxylate complex on the inner pore walls of the mesoporous silica host MCM-41 using the grafting method. Guest-host binding was achieved through double functionalization of the host surface with organosilane reagents (trimethylsilyl, TMS, and aminopropyltriethoxysilane, APTES) followed by reaction of the active amino sites of the APTES residue with the ligand 2,2'-bipyridyl-6,6'-dicarboxylic acid. Addition of EuCl3 solution dissolved in ethanol results in the formation of an immobilized complex having the probable formula Eu(L)x(3 ≥ x ≥ 1)(H2O)y, whose detailed photophysical properties were investigated. In the final step, an additional 2,2'-bipyridine-6 monocarboxylic acid ligand was added in an attempt to complete the coordination sphere of the rare earth ion. Each of the synthesis steps was monitored by (1)H, (13)C, and (29)Si solid state NMR spectroscopies, allowing for a quantitative assessment of the progress of the reaction and the influence of the paramagnetic species on the spectra. Based on these data and additional characterizations by chemical analysis, thermogravimetric analysis (TGA), N2 sorption, X-ray diffraction and FT-IR spectroscopy, a comprehensive quantitative picture of the covalent binding and complexation process was developed.

  16. Hybridization, ethnicity and cultural exchange in the Early Ptolemaic Egypt (S. IV-III A.C.

    Directory of Open Access Journals (Sweden)

    Agustín Ezequiel Saade

    2016-12-01

    Full Text Available Since the emergence of the New Cultural History in the late eighties, the historiographical production in the field of cultural studies seems endless. The multiplicity of concepts, some without further differentiation from the above or directly overlapped on content, received plenty of criticism, mostly because of the difficulty of combining theories with available sources as well as alleged epistemological weaknesses. In this article we propose an updated analysis of various models of cultural analysis used for the study of pre-capitalist societies. In particular, we propose a methodological approach that combines elements from anthropology, semiotics and history, to decide which concepts are more convenient when dealing with ancient sources. Also, in order to assess the relevance of these approaches to the analysis of Ancient History and specifically Hellenistic, we propose the implementation of some of the proposed conceptualizations of particular historical cases of our specialty, i.e. those linked to the shaping process of the Ptolemaic state (IV-III centuries BC.

  17. Identification of novel protein-protein interactions of Yersinia pestis type III secretion system by yeast two hybrid system.

    Directory of Open Access Journals (Sweden)

    Huiying Yang

    Full Text Available Type III secretion system (T3SS of the plague bacterium Y. pestis encodes a syringe-like structure consisting of more than 20 proteins, which can inject virulence effectors into host cells to modulate the cellular functions. Here in this report, interactions among the possible components in T3SS of Yersinia pestis were identified using yeast mating technique. A total of 57 genes, including all the pCD1-encoded genes except those involved in plasmid replication and partition, pseudogenes, and the putative transposase genes, were subjected to yeast mating analysis. 21 pairs of interaction proteins were identified, among which 9 pairs had been previously reported and 12 novel pairs were identified in this study. Six of them were tested by GST pull down assay, and interaction pairs of YscG-SycD, YscG-TyeA, YscI-YscF, and YopN-YpCD1.09c were successfully validated, suggesting that these interactions might play potential roles in function of Yersinia T3SS. Several potential new interactions among T3SS components could help to understand the assembly and regulation of Yersinia T3SS.

  18. Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I-II feasibility study.

    NARCIS (Netherlands)

    Schrijvers, D.; Herpen, C.M.L. van; Kerger, J.; Joosens, E.; Laer, C. van; Awada, A.; Weyngaert, D. van den; Nguyen, H.V.; Bouder, C. Le; Castelijns, J.A.; Kaanders, J.H.A.M.; Mulder, P.; Vermorken, J.B.

    2004-01-01

    PURPOSE: To determine the safety profile and activity of the combination of docetaxel, cisplatin and 5-fluorouracil (5-FU) in chemotherapy-naive patients with squamous cell carcinoma of the head and neck (SCCHN). PATIENTS AND METHODS: Patients with locally advanced unresectable SCCHN were treated wi

  19. Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer : a phase I-II feasibility study

    NARCIS (Netherlands)

    Schrijvers, D; Van Herpen, C; Kerger, J; Joosens, E; Van Laer, C; Awada, A; Van den Weyngaert, D; Nguyen, H; Le Bouder, C; Castelijns, JA; Kaanders, J; De Mulder, P; Vermorken, JB

    2004-01-01

    Purpose: To determine the safety profile and activity of the combination of docetaxel, cisplatin and 5-fluorouracil (5-FU) in chemotherapy-naive patients with squamous cell carcinoma of the head and neck (SCCHN). Patients and methods: Patients with locally advanced unresectable SCCHN were treated wi

  20. Realizing the Hybrid Library.

    Science.gov (United States)

    Pinfield, Stephen; Eaton, Jonathan; Edwards, Catherine; Russell, Rosemary; Wissenburg, Astrid; Wynne, Peter

    1998-01-01

    Outlines five projects currently funded by the United Kingdom's Electronic Libraries Program (eLib): HyLiFe (Hybrid Library of the Future), MALIBU (MAnaging the hybrid Library for the Benefit of Users), HeadLine (Hybrid Electronic Access and Delivery in the Library Networked Environment), ATHENS (authentication scheme), and BUILDER (Birmingham…

  1. The optically thick C III spectrum. 2: Level/term populations and line/multiplet intensities using an improved hybrid model

    Science.gov (United States)

    Bhatia, A. K.; Kastner, S. O.

    1993-01-01

    An improved hybrid level/term calculation is employed to obtain C III level/term populations and line/fractional multiplet intensities over the extended range of electron density 4.0 less than or equal log N(sub e) less than or equal 12.0, for column lengths L ranging from zero (optically thin) to 10(exp 20)/sq cm (moderately optically thick), at electron temperatures T(sub e) approximately 40,000 K(log T(sub e) = 4.6), T(sub e) approximately 63,000 K (log T(sub e) = 4.8), T(sub e) approximately 79,500 K (log T(sub e) = 4.9), and T(sub e) = 100,000 K (log T(sub e) = 5.0). The tabulated results are relevant to the interpretation of space observations obtained over extended spectral ranges by new and planned facilities including the Hopkins Ultraviolet Telescope (HUT) and the Far-Ultraviolet Spectrographic Explorer (FUSE).

  2. Edge Couplers with relaxed Alignment Tolerance for Pick-and-Place Hybrid Integration of III-V Lasers with SOI Waveguides

    CERN Document Server

    Romero-García, Sebastian; Merget, Florian; Shen, Bin; Witzens, Jeremy

    2013-01-01

    We report on two edge-coupling and power splitting devices for hybrid integration of III-V lasers with sub-micrometric silicon-on-insulator (SOI) waveguides. The proposed devices relax the horizontal alignment tolerances required to achieve high coupling efficiencies and are suitable for passively aligned assembly with pick-and-place tools. Light is coupled to two on-chip single mode SOI waveguides with almost identical power coupling efficiency, but with a varying relative phase accommodating the lateral misalignment between the laser diode and the coupling devices, and is suitable for the implementation of parallel optics transmitters. Experimental characterization with both a lensed fiber and a Fabry-P\\'erot semiconductor laser diode has been performed. Excess insertion losses (in addition to the 3 dB splitting) taken as the worst case over both waveguides of respectively 2 dB and 3.1 dB, as well as excellent 1 dB horizontal loss misalignment ranges of respectively 2.8 um and 3.8 um (worst case over both i...

  3. Accuracy of a Wearable Sensor for Measures of Head Kinematics and Calculation of Brain Tissue Strain.

    Science.gov (United States)

    Knowles, Brooklynn M; Yu, Henry; Dennison, Christopher R

    2017-02-01

    Wearable kinematic sensors can be used to study head injury biomechanics based on kinematics and, more recently, based on tissue strain metrics using kinematics-driven brain models. These sensors require in-situ calibration and there is currently no data conveying wearable ability to estimate tissue strain. We simulated head impact (n = 871) to a 50th percentile Hybrid III (H-III) head wearing a hockey helmet instrumented with wearable GForceTracker (GFT) sensors measuring linear acceleration and angular velocity. A GFT was also fixed within the H-III head to establish a lower boundary on systematic errors. We quantified GFT errors relative to H-III measures based on peak kinematics and cumulative strain damage measure (CSDM). The smallest mean errors were 12% (peak resultant linear acceleration) and 15% (peak resultant angular velocity) for the GFT within the H-III. Errors for GFTs on the helmet were on average 54% (peak resultant linear acceleration) and 21% (peak resultant angular velocity). On average, the GFT inside the helmet overestimated CSDM by 0.15.

  4. Pharyngeal airway space, hyoid bone position, and head posture after bimaxillary orthognathic surgery in Class III patients: long-term evaluation.

    Science.gov (United States)

    Efendiyeva, Ruchengiz; Aydemir, Halise; Karasu, Hakan; Toygar-Memikoğlu, Ufuk

    2014-09-01

    (1) To determine the effect of bimaxillary orthognathic surgery on pharyngeal airway, hyoid bone, and craniocervical posture in Class III bimaxillary surgery patients. (2) To evaluate short-term and long-term results. (3) To compare short- and long-term values. Twenty-six Class III adult patients treated with bimaxillary surgery were included in the study. Cephalometric records were taken before treatment (T1), before surgery (T2), and 5 months (T3), 1.4 years (T4), 3 years (T5), and 5 years (T6) postsurgery. No significant differences were identified in craniocervical angulation between time intervals. There was a significant superior movement of hyoid bone at postsurgery (T3; P bimaxillary surgery.

  5. Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.

    Science.gov (United States)

    Shrotriya, Sangeeta; Deep, Gagan; Lopert, Pamela; Patel, Manisha; Agarwal, Rajesh; Agarwal, Chapla

    2015-12-01

    Head and neck squamous cell carcinoma (HNSCC) is a major killer worldwide and innovative measures are urgently warranted to lower the morbidity and mortality caused by this malignancy. Aberrant redox and metabolic status in HNSCC cells offer a unique opportunity to specifically target cancer cells. Therefore, we investigated the efficacy of grape seed extract (GSE) to target the redox and bioenergetic alterations in HNSCC cells. GSE treatment decreased the mitochondrial electron transport chain complex III activity, increased the mitochondrial superoxide levels and depleted the levels of cellular antioxidant (glutathione), thus resulting in the loss of mitochondrial membrane potential in human HNSCC Detroit 562 and FaDu cells. Polyethylene glycol-SOD addition reversed the GSE-mediated apoptosis without restoring complex III activity. Along with redox changes, GSE inhibited the extracellular acidification rate (representing glycolysis) and oxygen consumption rate (indicating oxidative phosphorylation) leading to metabolic stress in HNSCC cells. Molecular studies revealed that GSE activated AMP-activated protein kinase (AMPK), and suppressed Akt/mTOR/4E-BP1/S6K signaling in both Detroit 562 and FaDu cells. Interestingly, GSE increased the autophagic load specifically in FaDu cells, and autophagy inhibition significantly augmented the apoptosis in these cells. Consistent with in vitro results, in vivo analyses also showed that GSE feeding in nude mice activated AMPK and induced-autophagy in FaDu xenograft tumor tissues. Overall, these findings are innovative as we for the first time showed that GSE targets ETC complex III and induces oxidative and metabolic stress, thereby, causing autophagy and apoptotic death in HNSCC cells. © 2014 Wiley Periodicals, Inc.

  6. The influence of personal protection equipment, occupant body size, and restraint system on the frontal impact responses of Hybrid III ATDs in tactical vehicles.

    Science.gov (United States)

    Zaseck, Lauren Wood; Orton, Nichole Ritchie; Gruber, Rebekah; Rupp, Jonathan; Scherer, Risa; Reed, Matthew; Hu, Jingwen

    2017-08-18

    Although advanced restraint systems, such as seat belt pretensioners and load limiters, can provide improved occupant protection in crashes, such technologies are currently not utilized in military vehicles. The design and use of military vehicles presents unique challenges to occupant safety-including differences in compartment geometry and occupant clothing and gear-that make direct application of optimal civilian restraint systems to military vehicles inappropriate. For military vehicle environments, finite element (FE) modeling can be used to assess various configurations of restraint systems and determine the optimal configuration that minimizes injury risk to the occupant. The models must, however, be validated against physical tests before implementation. The objective of this study was therefore to provide the data necessary for FE model validation by conducting sled tests using anthropomorphic test devices (ATDs). A secondary objective of this test series was to examine the influence of occupant body size (5th percentile female, 50th percentile male, and 95th percentile male), military gear (helmet/vest/tactical assault panels), seat belt type (3-point and 5-point), and advanced seat belt technologies (pretensioner and load limiter) on occupant kinematics and injury risk in frontal crashes. In total, 20 frontal sled tests were conducted using a custom sled buck that was reconfigurable to represent both the driver and passenger compartments of a light tactical military vehicle. Tests were performed at a delta-V of 30 mph and a peak acceleration of 25 g. The sled tests used the Hybrid III 5th percentile female, 50th percentile male, and 95th percentile male ATDs outfitted with standard combat boots and advanced combat helmets. In some tests, the ATDs were outfitted with additional military gear, which included an improved outer tactical vest (IOTV), IOTV and squad automatic weapon (SAW) gunner with a tactical assault panel (TAP), or IOTV and rifleman with

  7. 秋季专用平头甘蓝新品种锦秋60的选育%Breeding of Jinqiu 60, a New Cabbage F1 Hybrid with Flattened-shaped Head in Autumn

    Institute of Scientific and Technical Information of China (English)

    曾爱松; 宋立晓; 高兵; 严继勇

    2015-01-01

    Jinqiu 60 is a middle-maturing autumn cabbage F1 hybrid with flattened-shaped head, which was developed by Vegetable Crops Institute of Jiangsu Academy of Agricultural Sciences. It takes 70 days from transplanting to harvest, and Jinqiu 60 is suitable to be planted in South China in autumn. It has good adaptability and strong resistance to black rot, turnip mosaic virus (TuMV) and cabbage Fusarium wilt (CFW). Its leaf head is green and compact and has good quality. Its average head weight is about 1.5 kg and its yield is about 3 650 kg/667 m2.%锦秋60是江苏省农业科学院蔬菜研究所结合小孢子培养技术与常规育种技术选育的秋季专用平头中熟甘蓝新品种。该品种适宜我国南方地区秋季栽培,中熟,定植后70 d左右收获,适应性好,抗黑腐病、病毒病、枯萎病等病害;球形美观,颜色绿,品质佳;单球质量1.5 kg左右,每667 m2产量3650 kg左右。

  8. Evaluation of a radioactive and fluorescent hybrid tracer for sentinel lymph node biopsy in head and neck malignancies: prospective randomized clinical trial to compare ICG-{sup 99m}Tc-nanocolloid hybrid tracer versus {sup 99m}Tc-nanocolloid

    Energy Technology Data Exchange (ETDEWEB)

    Stoffels, Ingo; Leyh, Julia; Schadendorf, Dirk; Klode, Joachim [University Hospital Essen University of Duisburg-Essen, Department of Dermatology, Venerology and Allergology, Essen (Germany); University Duisburg-Essen, West German Cancer Center, Essen (Germany); German Cancer Consortium (DKTK), Essen (Germany); Poeppel, Thorsten [University Hospital Essen University of Duisburg-Essen, Department of Nuclear Medicine, Essen (Germany)

    2015-10-15

    There is some controversy about the value of sentinel lymph node excision (SLNE) in patients with head and neck malignancies. The gold standard for detection and targeted extirpation of the SLN is lymphoscintigraphy with {sup 99m}Tc-nanocolloid. The purpose of this prospective randomized study was to analyse the feasibility and clinical benefit of a hybrid tracer comprising the near-infrared (NIR) fluorescent indocyanine green (ICG) and {sup 99m}Tc-nanocolloid (ICG-{sup 99m}Tc-nanocolloid) in direct comparison with standard {sup 99m}Tc-nanocolloid for guiding SLNE in patients with head and neck cutaneous malignancies. We analysed the data from 40 clinically lymph node-negative patients with melanoma, high-risk cutaneous squamous cell carcinoma, Merkel cell carcinoma or sweat gland carcinoma who underwent SLNE with ICG-{sup 99m}Tc-nanocolloid (cohort A) or with the standard {sup 99m}Tc-nanocolloid (cohort B). Overall SLNs were identified preoperatively in all 20 patients (100 %) in cohort A and in 18 of 20 patients (90 %) in cohort B. The SLN basin was detected preoperatively in 18 patients (90 %) in cohort A and also in 18 patients (90 %) in cohort B. SLNs were identified intraoperatively in all 20 patients (100 %) in cohort A and in 19 patients (95 %) in cohort B (p = 0.487). Metastatic SLNs were detected in 9 patients (22.5 %), 3 (15.0 %) in cohort A and 6 (30.0 %) in cohort B (p = 0.228). The hybrid tracer ICG-{sup 99m}Tc-nanocolloid is an innovative imaging tracer, reliably and readily providing additional information for the detection and excision of SLN in the head and neck region. Therefore, SLNE with combined radioactive and NIR fluorescence guidance is an attractive option for improving the SLN detection rate in patients with cutaneous head and neck malignancies. (orig.)

  9. Cytogenetics of Triatominae: III - A study on male sterility induced through hybridization of Triatoma sórdida and Triatoma pseudomaculata

    Directory of Open Access Journals (Sweden)

    Giorgio Schreiber

    1975-08-01

    Full Text Available Males from bilateral crosses between Triatoma sórdida and Triatoma pseudomaculata were unable to give offspring, as shown by subsequent backcrosses (BC between hybrid males and parental females. This kind of sterility indueed through interspecific hybridization seems to be due to lack of sperm migration from the bursa copulatrix to the spermateca, thus suggesting primarily failure on the part of hybrid males to produce and/or to incorporate male accessory secretions into the spermatophore bulb. Addicional proof that sterility induced in hybrid males is at the sperm level has been afforded by the spermatogenesis herein studied. The anomalous processes like; 1 prophases of spermatogonia with the chromosomes scattered in the cytoplasm, 2 first metaphases with unpaired tetrades, 3 spermatids differing in size and 4 spermatozoa of abnormal shape and generdlly of giant size, can be taken as an indicator of the degree of departure from the normal course of spermatogenesis.

  10. Photophysical properties of a novel organic-inorganic hybrid material: Eu(III)-β-diketone complex covalently bonded to SiO(2) /ZnO composite matrix.

    Science.gov (United States)

    Li, Ya-Juan; Yan, Bing

    2010-01-01

    In this article, dibenzoylmethane (DBM) was first grafted with the coupling reagent 3-(triethoxysilyl)-propyl isocyanate (TESPIC) to form precursor DBM-Si, and ZnO quantum dot was modified with 3-mercaptopropyltrimethoxysilane (MPS) to form SiO(2) /ZnO nanocomposite particle. Then the precursor DBM-Si and the terminal ligand 1,10-phenthroline (phen) were coordinated to Eu(3+) ion to obtain ternary hybrid material phen-Eu-DBM-SiO(2) /ZnO after hydrolysis and copolycondensation between the tetraethoxysilane (TEOS), water molecules and the SiO(2) /ZnO network via the sol-gel process. In addition, for comparison, the binary hybrid material with SiO(2) /ZnO network and ternary hybrid material with pure Si-O network were also synthesized, denoted as Eu-DBM-SiO(2) /ZnO and phen-Eu-DBM-Si, respectively. The results reveal that hybrid material with SiO(2) /ZnO network phen-Eu-DBM-SiO(2) /ZnO exhibits the stronger red light, the longer lifetimes and higher quantum efficiency than hybrid material with pure Si-O network phen-Eu-DBM-Si, suggesting that SiO(2) /ZnO is a favorable host matrix for the luminescence of rare earth complexes.

  11. Evaluation of military helmets and roof padding on head injury potential from vertical impacts.

    Science.gov (United States)

    Franklyn, Melanie; Laing, Sheridan

    2016-10-02

    Soldiers in military vehicles subjected to underbelly blasts can sustain traumatic head and neck injuries due to a head impact with the roof. The severity of head and neck trauma can be influenced by the amount of head clearance available to the occupant as well as factors such as wearing a military helmet or the presence of padding on the interior roof. The aim of the current study was to examine the interaction between a Hybrid III headform, the helmet system, and the interior roof of the vehicle under vertical loading. Using a head impact machine and a Hybrid III headform, tests were conducted on a rigid steel plate in a number of different configurations and velocities to assess helmet shell and padding performance, to evaluate different vehicle roof padding materials, and to determine the relative injury mitigating contributions of both the helmet and the roof padding. The resultant translational head acceleration was measured and the head injury criterion (HIC) was calculated for each impact. For impacts with a helmeted headform hitting the steel plate only, which represented a common scenario in an underbelly blast event, velocities of ≤6 m/s resulted in HIC values below the FMVSS 201U threshold of 1,000, and a velocity of 7 m/s resulted in HIC values well over the threshold. Roof padding was found to reduce the peak translational head acceleration and the HIC, with rigid IMPAXX foams performing better than semirigid ethylene vinyl acetate (EVA) foam. However, the head injury potential was reduced considerably more by wearing a helmet than by the addition of roof padding. The results of this study provide initial quantitative findings that provide a better understanding of helmet-roof interactions in vertical impacts and the contributions of the military helmet and roof padding to mitigating head injury potential. Findings from this study will be used to inform further testing with the future aim of developing a new minimum head clearance standard for

  12. Speciation of As(III)/As(V) in water samples by a magnetic solid phase extraction based on Fe₃O₄/Mg-Al layered double hydroxide nano-hybrid followed by chemiluminescence detection.

    Science.gov (United States)

    Abdolmohammad-Zadeh, Hossein; Talleb, Zeynab

    2014-10-01

    A novel magnetic solid phase extraction method was developed for the speciation of As(III)/As(V) in aqueous solutions utilizing Fe3O4-doped Mg-Al layered double hydroxide (LDH) as a nano-sorbent. The method is based on the separation and pre-concentration of As(V) by Fe3O4/Mg-Al LDH nano-hybrid prior to determination by a chemiluminescence (CL) technique. The CL route involves the oxidation of luminol by vanadomolybdoarsenate heteropoly acid in a basic media. Since the existing cations cannot be adsorbed by positively charged layers of the LDH and other potentially interferent anions had no considerable effect on the CL reaction, it provides a very selective and sensitive determination approach for As(V). The determination of total arsenic and hence indirectly As(III) involve the pre-oxidation of As(III) to As(V) by a mixture of hydrogen peroxide and potassium hydroxide. Several factors affecting the extraction and determination of the analyte were investigated and optimized. Under optimum conditions, the calibration graph was linear in the range of 5.0-5000 ng L(-1). The limit of detection and enrichment factor was 2.0 ng L(-1) and 80, respectively. The method was validated by the analysis of a standard reference material (NIST SRM 1643e), and successfully applied to the speciation of arsenic in several water samples with recoveries in the range of 93.3-106.7% for the spiked samples.

  13. Structure and properties of metal-exchanged zeolites studied using gradient-corrected and hybrid functionals. III. Energetics and vibrational spectroscopy of adsorbates.

    Science.gov (United States)

    Göltl, Florian; Hafner, Jürgen

    2012-02-14

    The influence of the exchange-correlation functional (semilocal gradient corrected or hybrid functional) on density-functional studies of the adsorption of CO and NO in Cu- and Co-exchanged chabazite has been investigated, extending the studies of the structural and electronic properties of these materials [F. Göltl and J. Hafner, J. Chem. Phys. 136, 064501 (2012); 136, 064502 (2012)] and including for comparison carbonyls and nitrosyls of Cu and Co. Hybrid functionals predict much lower adsorption energies than conventional semilocal functionals, in better agreement with experiment as far as data are available for comparison. The calculated adsorption energies show a strong linear correlation with the stability of the cation sites. For Cu(I)-chabazite the calculated adsorption energies span almost the interval between the adsorption energies calculated for pure neutral and positively charged Cu-carbonyls and nitrosyls. For divalent Cu(II) and Co(II) the adsorption energies at cations in chabazite are much lower than the metal-molecule binding energies in the free carbonyls or nitrosyls, especially for the most stable cation location in a six-membered ring of the chabazite structure. For the stretching modes of adsorbed CO only hybrid functionals reproduce the blueshift of the frequency reported for all Cu(I)- and Co(II)-zeolites. For Cu(II)-chabazite both types of functionals predict a blueshift, the larger value calculated with hybrid functionals being in better agreement with observation. For NO adsorbed on Cu(I)-chabazite all functionals produce a redshift, the smaller value derived with hybrid functionals being in better agreement with experiment. For NO adsorbed in Cu(II)- and Co(II)-chabazite gradient-corrected functionals produce the best agreement with experiment for cations located in a six-membered ring. Semilocal functionals tend to underestimate the frequencies, while hybrid functionals tend to overestimate. The decisive factors determining the

  14. Hybrid III-V/SOI single-mode vertical-cavity laser with in-plane emission into a silicon waveguide

    DEFF Research Database (Denmark)

    Park, Gyeong Cheol; Xue, Weiqi; Semenova, Elizaveta;

    2015-01-01

    We report a III-V-on-SOI vertical-cavity laser emitting into an in-plane Si waveguide fabricated by using CMOS-compatible processes. The fabricated laser operates at 1.54 µm with a SMSR of 33 dB and a low threshold.......We report a III-V-on-SOI vertical-cavity laser emitting into an in-plane Si waveguide fabricated by using CMOS-compatible processes. The fabricated laser operates at 1.54 µm with a SMSR of 33 dB and a low threshold....

  15. Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: results of the randomized phase I/II ADVANTAGE trial (phase II part).

    Science.gov (United States)

    Vermorken, J B; Peyrade, F; Krauss, J; Mesía, R; Remenar, E; Gauler, T C; Keilholz, U; Delord, J P; Schafhausen, P; Erfán, J; Brümmendorf, T H; Iglesias, L; Bethe, U; Hicking, C; Clement, P M

    2014-03-01

    Recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN) overexpresses αvβ5 integrin. Cilengitide selectively inhibits αvβ3 and αvβ5 integrins and is investigated as a treatment strategy. The phase I/II study ADVANTAGE evaluated cilengitide combined with cisplatin, 5-fluorouracil, and cetuximab (PFE) in R/M-SCCHN. The phase II part reported here was an open-label, randomized, controlled trial investigating progression-free survival (PFS). Patients received up to six cycles of PFE alone or combined with cilengitide 2000 mg once (CIL1W) or twice (CIL2W) weekly. Thereafter, patients received maintenance therapy (cilengitide arms: cilengitide plus cetuximab; PFE-alone arm: cetuximab only) until disease progression or unacceptable toxicity. One hundred and eighty-two patients were treated. Median PFS per investigator read was similar for CIL1W + PFE, CIL2W + PFE, and PFE alone (6.4, 5.6, and 5.7 months, respectively). Accordingly, median overall survival and objective response rates were not improved with cilengitide (12.4 months/47%, 10.6 months/27%, and 11.6 months/36%, respectively). No clinically meaningful safety differences were observed between groups. None of the tested biomarkers (expression of integrins, CD31, Ki-67, vascular endothelial growth factor receptor 2, vascular endothelial-cadherin, type IV collagen, epidermal growth factor receptor, or p16 for human papillomavirus) were predictive of outcome. Neither of the cilengitide-containing regimens demonstrated a PFS benefit over PFE alone in R/M-SCCHN patients.

  16. Error-free Dispersion-uncompensated Transmission at 20 Gb/s over SSMF using a Hybrid III-V/SOI DML with MRR Filtering

    DEFF Research Database (Denmark)

    Cristofori, Valentina; Kamchevska, Valerija; Ding, Yunhong

    2016-01-01

    Error-free 20-Gb/s directly-modulated transmission is achieved by enhancing the dispersion tolerance of a III-V/SOI DFB laser with a silicon micro-ring resonator. Low (∼0.4 dB) penalty compared to back-to-back without ring is demonstrated after 5-km SSMF....

  17. Production of Group II and III base oils by hybrid route using brazilian crude; Producao de oleos basicos lubrificantes dos grupos II e III pela rota hibrida ou mista a partir de petroleo brasileiro

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Wlamir Soares; Fontes, Anita Eleonora Ferreira [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES)

    2004-07-01

    This paper describes a series of pilot plant tests made at PETROBRAS Research Centre, considering hydrotreatment and solvent dewaxing steps, to produce group II and group III lube base oils from Baiano Light crude feeds (Brazilian crude). RLAM Refinery has been using Baiano light crude to produce group I base oils by conventional route and in the pilot plant studies, two types of process scheme were tested. In the first one, an industrial run was performed at RLAM Refinery, including distillation, dewaxing and extraction and the light raffinate was used as a feed for a hydrotreatment pilot plant, followed by a distillation to remove the front ends. In the second scheme, another industrial run was performed, including distillation and dewaxing steps and the medium dewaxed oil was used as a charge for a hydrotreatment followed by distillation and dewaxing pilot plant tests. Products of excellent quality were obtained. Due to their high viscosity indexes (from 96 to 126), low contaminants levels (sulfur < 5 ppm and nitrogen < 5 ppm) and low aromatic content (CA < 2 %), the lube base oils produced are therefore classified as group II and group III. The main advantages of this route are related to the base oils quality improvements with low investment and more flexibility in terms of crude source. (author)

  18. Crystal structure of the new hybrid material bis(1,4-diazoniabicyclo[2.2.2]octane di-μ-chlorido-bis[tetrachloridobismuthate(III] dihydrate

    Directory of Open Access Journals (Sweden)

    Marwen Chouri

    2015-11-01

    Full Text Available The title compound bis(1,4-diazoniabicyclo[2.2.2]octane di-μ-chlorido-bis[tetrachloridobismuthate(III] dihydrate, (C6H14N22[Bi2Cl10]·2H2O, was obtained by slow evaporation at room temperature of a hydrochloric aqueous solution (pH = 1 containing bismuth(III nitrate and 1,4-diazabicyclo[2.2.2]octane (DABCO in a 1:2 molar ratio. The structure displays a two-dimensional arrangement parallel to (100 of isolated [Bi2Cl10]4− bioctahedra (site symmetry -1 separated by layers of organic 1,4-diazoniabicyclo[2.2.2]octane dications [(DABCOH22+] and water molecules. O—H...Cl, N—H...O and N—H...Cl hydrogen bonds lead to additional cohesion of the structure.

  19. Biosynthesis of Dictyostelium Discoideum Differentation-Inducing Factor by a Hybrid Type I Fatty Acid A-Type III polyketide synthase

    Energy Technology Data Exchange (ETDEWEB)

    Austin,M.; Saito, T.; Bowman, M.; Haydock, S.; Kato, A.; Moore, B.; Kay, R.; Noel, J.

    2006-01-01

    Differentiation-inducing factors (DIFs) are well known to modulate formation of distinct communal cell types from identical Dictyostelium discoideum amoebas, but DIF biosynthesis remains obscure. We report complimentary in vivo and in vitro experiments identifying one of two {approx}3,000-residue D. discoideum proteins, termed 'steely', as responsible for biosynthesis of the DIF acylphloroglucinol scaffold. Steely proteins possess six catalytic domains homologous to metazoan type I fatty acid synthases (FASs) but feature an iterative type III polyketide synthase (PKS) in place of the expected FAS C-terminal thioesterase used to off load fatty acid products. This new domain arrangement likely facilitates covalent transfer of steely N-terminal acyl products directly to the C-terminal type III PKS active sites, which catalyze both iterative polyketide extension and cyclization. The crystal structure of a steely C-terminal domain confirms conservation of the homodimeric type III PKS fold. These findings suggest new bioengineering strategies for expanding the scope of fatty acid and polyketide biosynthesis.

  20. Docetaxel, cisplatin and 5-fluorouracil induction chemotherapy followed by chemoradiotherapy or chemoradiotherapy alone in stage III-IV unresectable head and neck cancer. Results of a randomized phase II study

    Energy Technology Data Exchange (ETDEWEB)

    Takacsi-Nagy, Zoltan; Polgar, Csaba; Major, Tibor; Fodor, Janos [National Institute of Oncology, Center of Radiotherapy, Budapest (Hungary); Hitre, Erika [National Institute of Oncology, Department of Chemotherapy and Clinical Pharmacology, Budapest (Hungary); Remenar, Eva; Kasler, Miklos [National Institute of Oncology, Department of Head and Neck and Maxillofacial Surgery, Budapest (Hungary); Oberna, Ferenc [Bacs-Kiskun County Hospital, Department of Oral, Maxillofacial and Head and Neck Surgery, Kecskemet (Hungary); Goedeny, Maria [National Institute of Oncology, Department of Radiology, Budapest (Hungary)

    2015-08-15

    Concurrent chemoradiotherapy (CRT) is the standard treatment for advanced head and neck squamous cell carcinoma. In this phase II randomized study, the efficacy and toxicity of docetaxel, cisplatin and 5-fluorouracil induction chemotherapy (ICT) followed by concurrent CRT was compared with those after standard CRT alone in patients with locally advanced, unresectable head and neck cancer. Between January 2007 and June 2009, 66 patients with advanced (stage III or IV) unresectable squamous cell carcinoma of the head and neck (oral cavity, oropharynx, hypopharynx, and larynx) were randomly assigned to two groups: one receiving two cycles of docetaxel, cisplatin, and 5-fluorouracil ICT followed by CRT with three cycles of cisplatin and one treated by CRT alone. Response rate, local tumor control (LTC), locoregional tumor control (LRTC), overall survival (OS), progression-free survival (PFS), and toxicity results were assessed. Three patients from the ICT + CRT group did not appear at the first treatment, so a total of 63 patients were evaluated in the study (30 ICT + CRT group and 33 CRT group). Three patients died of febrile neutropenia after ICT. The median follow-up time for surviving patients was 63 months (range 53-82 months). The rate of radiologic complete response was 63 % following ICT + CRT, whereas 70 % after CRT alone. There were no significant differences in the 3-year rates of LTC (56 vs. 57 %), LRTC (42 vs. 50 %), OS (43 vs. 55 %), and PFS (41 vs. 50 %) in the ICT + CRT group and in the CRT group, respectively. The rate of grade 3-4 neutropenia was significantly higher in the ICT + CRT group than in the CRT group (37 and 12 %; p = 0.024). Late toxicity (grade 2 or 3 xerostomia) developed in 59 and 42 % in the ICT + CRT and CRT groups, respectively. The addition of ICT to CRT did not show any advantage in our phase II trial, while the incidence of adverse events increased. The three deaths as a consequence of ICT call attention to the importance of

  1. Cytogenetics of Triatominae: III - A study on male sterility induced through hybridization of Triatoma sórdida and Triatoma pseudomaculata

    Directory of Open Access Journals (Sweden)

    Giorgio Schreiber

    1975-08-01

    Full Text Available Males from bilateral crosses between Triatoma sórdida and Triatoma pseudomaculata were unable to give offspring, as shown by subsequent backcrosses (BC between hybrid males and parental females. This kind of sterility indueed through interspecific hybridization seems to be due to lack of sperm migration from the bursa copulatrix to the spermateca, thus suggesting primarily failure on the part of hybrid males to produce and/or to incorporate male accessory secretions into the spermatophore bulb. Addicional proof that sterility induced in hybrid males is at the sperm level has been afforded by the spermatogenesis herein studied. The anomalous processes like; 1 prophases of spermatogonia with the chromosomes scattered in the cytoplasm, 2 first metaphases with unpaired tetrades, 3 spermatids differing in size and 4 spermatozoa of abnormal shape and generdlly of giant size, can be taken as an indicator of the degree of departure from the normal course of spermatogenesis.Os machos provenientes de cruzamentos bilaterais entre Triatoma sórdida e Triatoma pseudomaculata revelaram a incapacidade de produzir progênie, como se demonstra nos retrocruzamentos de machos híbridos com fêmeas das espécies paternas. Esta modalidade de esterilidade induzida através da hibridação interespecífica, parece ser devida à ausência de migração do esperma, determinada pela incapacidade dos híbridos machos produzirem a secreção opaca em suas glândulas acessórias e/ou incorporá-la à luz do espermatóforo. A prova adicional de que a incompatibilidade induzida em triatomíneos, através da hibridação inter específica, está no nível do esperma é fornecida pelo tipo anômalo de espermatogênese em híbridos aqui descrito, mostrando deste modo que: as prófases espermatogoniais têm os núcleos disruptos e os cromossomos espelhados no citoplasma. As primeiras metáfases meióticas têm as tétrades desemparelhadas. Os grupos de cromatídes assim obtidos

  2. Head Injuries

    Science.gov (United States)

    ... object that's stuck in the wound. previous continue Concussions Concussions — the temporary loss of normal brain function due ... also a type of internal head injury. Repeated concussions can permanently damage the brain. In many cases, ...

  3. Head Tilt

    Science.gov (United States)

    ... Healthy Living Healthy Living Healthy Living Nutrition Fitness Sports Oral Health Emotional Wellness Growing Healthy Sleep Safety & ... When this happens, the neck muscles go into spasm, causing the head to tilt to one side. ...

  4. Head Injuries

    Science.gov (United States)

    ... ATV) Safety Balance Disorders Knowing Your Child's Medical History First Aid: Falls First Aid: Head Injuries Preventing Children's Sports Injuries Getting Help: Know the Numbers Concussions Stay Safe: Baseball Concussions Concussions: Getting Better Sports and Concussions Dealing ...

  5. Head MRI

    Science.gov (United States)

    ... heart valves Heart defibrillator or pacemaker Inner ear (cochlear) implants Kidney disease or dialysis (you may not ... to: Abnormal blood vessels in the brain ( arteriovenous malformations of the head ) Tumor of the nerve that ...

  6. Coordenação local do Eu(III em híbridos orgânicos/inorgânicos emissores de luz branca Eu(III local coordination in white light emitters organic-inorganic hybrids

    Directory of Open Access Journals (Sweden)

    Luís D. Carlos

    2001-08-01

    Full Text Available Eu3+ luminescence and EXAFS (Extended X-ray Absorption Fine Structure results are presented for organic-inorganic hybrid gel hosts composed of a siliceous network to which small chains of oxyethylene units are covalently grafted by means of urea bridges. Coordination numbers for Eu3+ ions range from 12.8 to 9.7 with increasing Eu3+ concentration while the Eu3+-first neighbours mean distance is found to be constant at 2.48-2.49 Å in the same concentration range. Emission spectra display a broad band in the green/blue spectral region superposed to narrow lines appearing in the yellow/red region in such a way that for the eyes emission appears white. The broad band is assigned to intrinsic NH groups emission and also to electron-hole recombination in the nanosised siliceous domains. The narrow lines are assigned to intra-4f6, 5D0->7F0-4 Eu3+ transitions and from the energy position of the 7F0-4 levels a mean distance could be calculated for the Eu3+-first neighbours. The calculated results are in good agreement with the experimental ones obtained from EXAFS analysis.

  7. Measurement of Head Impact Due to Standing Fall in Adults Using Anthropomorphic Test Dummies.

    Science.gov (United States)

    Hajiaghamemar, Marzieh; Seidi, Morteza; Ferguson, James R; Caccese, Vincent

    2015-09-01

    The kinematics and kinetics of head impact due to a standing fall onto a hard surface are summarized. Head injury due to impact from falls represents a significant problem, especially for older individuals. When the head is left unprotected during a fall, the impact severity can be high enough to cause significant injury or even death. To ascertain the range of head impact parameters, the dynamic response was captured for the pedestrian version of the 5th percentile female and 50th percentile male Hybrid III anthropomorphic test dummies as they were dropped from a standing position with different initial postures. Five scenarios of falls were considered including backward falls with/without hip flexion, forward falls with/without knee flexion and lateral falls. The results show that the head impact parameters are dependent on the fall scenario. A wide range of impact parameters was observed in 107 trials. The 95% prediction interval for the peak translational acceleration, peak angular acceleration, peak force, impact translational velocity and peak angular velocity are 146-502 g, 8.8-43.3 krad/s(2), 3.9-24.5 kN, 2.02-7.41 m/s, and 12.9-70.3 rad/s, respectively.

  8. Research on genetics of rice heading date

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Heading date is one of the most important traits for rice adaptation to cultivation area and crop seasons, and it is mainly determined by photoperiod, basic vegetative growth, and temperature of cultivars. The diversity of combinations of photo-sensitive varieties and the basic vegetative, makes the heading date varied. On one hand, this supplies abundant resources for different ecotypes breeding; on the other hand, it complicates the inheritance of heading date. In recent years, transgression of late maturity has often been encountered, especially between indica and japonica subspecies, this had inhabited the use of hybrid vigor. Therefore, understanding the inheritance basis of heading date is very important for breeding practices.

  9. Enhanced emission from Eu(III) beta-diketone complex combined with ether-type oxygen atoms of di-ureasil organic-inorganic hybrids

    CERN Document Server

    Molina, C; Messaddeq, Y; Ribeiro, S J L; Silva, M A P; Zea-Bermudez, V D; Carlos, L D

    2003-01-01

    Organic-inorganic hybrids, named di-ureasils and described by polyether-based chains grafted to both ends to a siliceous backbone through urea cross linkages, were used as hosts for incorporation of the well-known coordination complex of trivalent europium (Eu sup 3 sup +) ions described by the formula [Eu(TTA) sub 3 (H sub 2 O) sub 2] (where TTA stands for thenoyltrifluoroacetone). By comparing with Eu sup 3 sup + -doped di-ureasil without complex form the new materials prepared here enhanced the quantum efficiency for photoemission of Eu sup 3 sup + ions. The enhancement can be explained by the coordination ability of the organic counterpart of the host structure which is strong enough to displace water molecules in [Eu(TTA) sub 3 (H sub 2 O) sub 2] from the rare earth neighbourhood after the incorporation process. High intensity of Eu sup 3 sup + emission was observed with a low non-radiative decay rate under ultraviolet excitation. The quantum efficiency calculated from the decay of sup 5 D sub 0 emission...

  10. New Quasi-One-Dimensional Organic-Inorganic Hybrid Material: 1,3-Bis(4-piperidiniumpropane Pentachlorobismuthate(III Synthesis, Crystal Structure, and Spectroscopic Studies

    Directory of Open Access Journals (Sweden)

    Hela Ferjani

    2014-01-01

    Full Text Available The organic-inorganic hybrid compound (C13H28N2 BiCl5 was synthesized by solvothermal method. The crystal structure was solved by single-crystal X-ray diffraction. The compound crystallizes in the orthorhombic system space group Cmc21 with a=15.826(4 Å, b=18.746(6 Å, c=7.470(3 Å, and Z=4. The crystal structure was refined down to R=0.019. It consists of corrugated layers of [BiCl5]2− chains, separated by organic [H2TMDP]2+ cations (TMDP=1,3-Bis(4-piperidylpropane = C13H26N2. The crystal cohesion is achieved by hydrogen bonds N–H⋯Cl joining the organic and inorganic layers. The influence of the organic cations' flexibility is discussed. Raman and infrared spectra of the title compound were recorded in the range of 50–400 and 400–4000 cm−1, respectively. Semiempirical parameter model three (PM3 method has been performed to derive the calculated IR spectrum. The crystal shape morphology was simulated using the Bravais-Friedel and Donnay-Harker model.

  11. Head Start.

    Science.gov (United States)

    Greenman, Geri

    2000-01-01

    Discusses an art project in which students created drawings of mop heads. Explains that the approach of drawing was more important than the subject. States that the students used the chiaroscuro technique, used by Rembrandt and Caravaggio, in which light appears out of the darkness. (CMK)

  12. Performance of the Tibet hybrid experiment (YAC-II + Tibet-III + MD) to measure the energy spectra of the light primary cosmic rays at energies 50-10,000 TeV

    Science.gov (United States)

    Huang, J.; Zhai, L. M.; Chen, D.; Shibata, M.; Katayose, Y.; Zhang, Ying; Liu, J. S.; Chen, Xu; Hu, X. B.; Zhang, X. Y.; Jia, H. Y.; Danzengluobu; Ohnishi, M.; Takita, M.

    2015-06-01

    A new hybrid detector system has been constructed by the Tibet ASγ collaboration at Tibet, China, since 2014 to measure the chemical composition of cosmic rays around the knee in the wide energy range. They consist of an air-shower-core detector-grid (YAC-II) to detect high energy electromagnetic component, the Tibet air-shower array (Tibet-III) and a large underground water-Cherenkov muon-detector array (MD). We have carried out a detailed air-shower Monte Carlo (MC) simulation to study the performance of the hybrid detectors by using CORSIKA (version 6.204), which includes QGSJET01c and SIBYLL2.1 hadronic interaction models. Assumed primary cosmic ray models are based on helium poor, helium rich and Gaisser's fit compositions around the knee. All detector responses are calculated using Geant4 (version 9.5) according to the real detector configurations and the MC events are reconstructed by the same procedure as the experimental data analysis. The energy determination is made by lateral density fitting (LDF) method using modified NKG function and the separation of the light components (proton, helium) is made by means of the artificial neural network (ANN) method and the random forest (RF) method. The systematic errors of the spectra of proton and helium caused by each steps of the analysis procedure are investigated including the dependence of the MC data on the hadronic interaction models and the primary composition models, and the algorithms for the primary mass identification. The systematic errors of the flux to be obtained by the new experiment are summarized as less than 30% in total. Our results show that the new hybrid experiment is powerful enough to study the chemical composition of the cosmic rays, in particular, to obtain the light-component spectra of the primary cosmic rays in 50-10,000 TeV energy range overlapping to the direct observation data at low energy side and ground-based indirect observations at high energy side. It is possible in this

  13. Hybrid silicon evanescent devices

    Directory of Open Access Journals (Sweden)

    Alexander W. Fang

    2007-07-01

    Full Text Available Si photonics as an integration platform has recently been a focus of optoelectronics research because of the promise of low-cost manufacturing based on the ubiquitous electronics fabrication infrastructure. The key challenge for Si photonic systems is the realization of compact, electrically driven optical gain elements. We review our recent developments in hybrid Si evanescent devices. We have demonstrated electrically pumped lasers, amplifiers, and photodetectors that can provide a low-cost, scalable solution for hybrid integration on a Si platform by using a novel hybrid waveguide architecture, consisting of III-V quantum wells bonded to Si waveguides.

  14. Synthesis, characterization and antioxidant activity of a novel organic-inorganic hybrid material trans-2,5-dimethylpiperazine-1,4-diium pentachlorobismuthate(III): [C6H16N2]BiCl5

    Science.gov (United States)

    Essid, Manel; Rzaigui, Mohamed; Marouani, Houda

    2016-08-01

    A novel organic-inorganic hybrid compound, trans-2,5-dimethylpiperazine-1,4-diium pentachlorobismuthate(III), [C6H16N2]BiCl5, was synthesized and its structure determined by means of single crystal X-ray diffraction studies. It crystallizes in the monoclinic space group C2/c, with the following parameters: a = 15.365(5), b = 12.634(3), c = 8.313(3) Å, β = 120.59(3)°, Z = 4 and V = 1389.1(7) Å3. Its crystal structure consists of [BiCl5]2- anions surrounded by [C6H16N2]2+ cations. Complex hydrogen bonding interactions between [BiCl5]2- and organic cations through N(C)-H … Cl hydrogen bonds to form a three-dimensional network. The crystal packing is stabilized by Cl … Cl interactions. The structure reveals that the piperazine ring is in a chair conformation. The vibrational spectrum has been measured at room temperature by FT-infrared spectroscopy (4000-400 cm-1) on polycrystalline samples. The number of the NMR components in the 13C CP-MAS NMR spectrum proves the presence of three crystallographically independent carbons as revealed by X-ray structure determination. Investigation of antioxidant activity of compound was carried out by 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical, Ferric Reducing Power (FRP) and Ferrous ion chelating (FIC) methods. The synthesized compound exhibited significant antioxidant activities.

  15. Synthesis, property and crystal structure of a novel two-dimensional network organic-inorganic hybrid compound based on the neodymium III center and Keggin-type heteropolyanion of [α-BW 12O 40] 5-

    Science.gov (United States)

    Niu, Jingyang; Zhao, Junwei; Wang, Jingping; Ma, Pengtao

    2004-08-01

    A novel two-dimensional infinite network organic-inorganic hybrid neodymium(III)-centered compound of formula (dmaH) 2[Nd(dmf) 4(H 2O)][α-BW 12O 40]·H 2O ( 1) [dma=dimethylamine and dmf= N, N-dimethylformamide] is obtained by the conventional self-assembly reaction of neodymium oxide, N, N-dimethylformamide and borotungstic acid (α-H 5BW 12O 40·30H 2O) in the mixed solvent of acetonitrile and water, and characterized by IR, UV-visible spectra and X-ray single crystal diffraction. Structural analysis indicates that every [α-BW 12O 40] 5- polyanion interconnects with three adjacent [Nd(dmf) 4(H 2O)] 3+ subunits by means of W-O-Nd bridges, meanwhile, every [Nd(dmf) 4(H 2O)] 3+ building block is surrounded by three neighboring [α-BW 12O 40] 5- polyanions by making use of which an unprecedented two-dimensional extended network structure can be constructed. Interestingly, this structure pattern may act as useful model for the design and assembly of functional molecule-based compounds, especially in the field of molecular sieve materials.

  16. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Computed Tomography (CT) - Head Computed tomography (CT) of the head uses special ... the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a CT ...

  17. Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).

    NARCIS (Netherlands)

    Hoebers, F.J.; Pluim, D.; Verheij, M.; Balm, A.J.M.; Bartelink, H.; Schellens, J.H.M.; Begg, A.C.

    2006-01-01

    The purpose of our study was to test the predictive value of cisplatin-DNA adduct levels in head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin-radiation. Patients with advanced-stage HNSCC were treated within a randomized trial, investigating the optimal route of cisplatin

  18. Making a Difference in the Lives of Infants and Toddlers and Their Families: The Impacts of Early Head Start. Volumes I-III: Final Technical Report [and] Appendixes [and] Local Contributions to Understanding the Programs and Their Impacts.

    Science.gov (United States)

    Love, John M.; Kisker, Ellen Eliason; Ross, Christine M.; Schochet, Peter Z.; Brooks-Gunn, Jeanne; Paulsell, Diane; Boller, Kimberly; Constantine, Jill; Vogel, Cheri; Fuligni, Alison Sidle; Brady-Smith, Christy

    Early Head Start was designed in 1994 as a 2-generation program to enhance children's development and health, strengthen family and community partnerships, and support the staff delivering new services to low-income families with pregnant women, infants, or toddlers. This document contains the final technical report, appendixes, and local…

  19. Head Position and Internally Headed Relative Clauses.

    Science.gov (United States)

    Basilico, David

    1996-01-01

    Examines "Head Movement" in internally headed relative clauses (IHRCs). The article shows that in some cases, head movement to an external position need not take place and demonstrates that this movement of the head to a sentence-internal position results from the quantificational nature of IHRCs and Diesing's mapping hypothesis (1990, 1992). (56…

  20. AMMI Model Based Analysis on Head Milled Rice Rate of Hybrid indica Rice in China%利用AMMI模型分析我国杂交籼稻整精米率

    Institute of Scientific and Technical Information of China (English)

    卢林; 朱智伟; 段彬伍

    2012-01-01

    利用AMMI模型分析了6种杂交籼稻在我国5个籼稻亚区平均整精米率,以评价我国杂交籼稻整精米率的稳定性、地区适应性等.结果表明,两优培九的整精米率较高且稳定性优;Ⅱ优838、丰两优1号的整精米率较高但稳定性较差;D优527、金优207的整精米率虽低但稳定性较好;冈优725的整精米率较低且稳定性最差.D优527、冈优725、金优207在浙、沪、苏稻亚区表现较好的适应性;两优培九、Ⅱ优838、丰两优1号在琼粤桂稻亚区、闽台稻亚区、皖赣鄂湘稻亚区、滇黔川渝稻亚区表现较好的适应性.皖赣鄂湘稻亚区、滇黔川渝稻亚区的交互作用小且品种辨别力弱,另外3个则不然.因此,我国籼稻整精米率以基因型与环境的互作效应最大,基因效应其次,环境效应相对较小.%Head milled rice rate CHMRR) of six scries of indica hybrid rice from five rice growing regions was analyzed by using additive maineffects and multiplicative interaction( AMMI) model. The stability and adaptability of HMRR of indica hybrid rice were evaluated by analysis on genotype, environment effect and genotype×environment interaction. The results showed that Liangyoupeijiu had higher HMRR and excellent stability. HMRR of Ⅱ you 838 and Fengliangyou 1 was higher but less stable. Dyou 527 and Jinyou 207 had low HMRR but better stability. HMRR of Gangyou 725 was low and worst stable. Dyou 527, Gangyou 725 and Jinyou 207 performed better adaptability in rice growing region of Zbejiang, Shanghai and Jiangsu. Liangyoupeijiu, Ⅱ you 838 and Fengliangyou 1 showed good adaptability in other four regions. The rice growing region of Anhui.Jiangxi.Hubei and Hunan and rice growing region of Yunnan. Guizhou. Sichuan and Chongqing .showed weak interaction and ability to distinguish cultivars. It is concluded that genotypeXenvironment interaction effect has greater influence on HMRR.

  1. 不结球白菜新品种速俊028的选育%A New Non-heading Chinese Cabbage F1 Hybrid-‘Sujun 028’

    Institute of Scientific and Technical Information of China (English)

    黄志银; 张斌; 闻凤英; 刘晓晖; 罗智敏; 王超楠; 李梅

    2014-01-01

    ‘Sujun 028’is a new non-heading Chinese cabbage F1 hybrid bred by crossing 2 self-incompatible lines 08-411-5s and 07-N2 kangre-3s.It grows fast with beautiful plant type.It is about 20 cm in height and about 25 cm in width.The leaf is glossy green and the petiole is short without wax powder.It is early maturing.In summer and autumn sowing,it takes only 20 days to bean waist.It can be planted with appropriate density.The best planting density is 8 cm in row spacing and 15 cm in line spacing.It is highly resistant to virus disease,downy mildew and resistant to soft rot.It has wide adaptability,and is suitable for summer and autumn cultivation all over the country.For winter and spring cultivation,it can be grown in open fields in the southern areas of the Yangtze River,but in the norther areas of the Yangtze River it has to be planted in protected fields.%速俊028是由两个自交不亲和系08-411-5s和07-N2抗热-3s配制而成的不结球白菜一代杂种。株型美观,株高20cm左右,开展度25cm左右;叶色亮绿,叶柄较短、勺状、碧绿无蜡粉,基部头大、束腰;早熟,生长速度快,夏秋季播种20d(天)后开始束腰;可适当密植,最佳种植密度为株距8cm,行距15cm;高抗病毒病、霜霉病,抗软腐病;适应性广,全国各地夏秋季均可种植,长江以南地区冬春季可露地栽培,长江以北地区秋冬季和冬春季需保护地种植。

  2. Validation of a noninvasive system for measuring head acceleration for use during boxing competition.

    Science.gov (United States)

    Beckwith, Jonathan G; Chu, Jeffrey J; Greenwald, Richard M

    2007-08-01

    Although the epidemiology and mechanics of concussion in sports have been investigated for many years, the biomechanical factors that contribute to mild traumatic brain injury remain unclear because of the difficulties in measuring impact events in the field. The purpose of this study was to validate an instrumented boxing headgear (IBH) that can be used to measure impact severity and location during play. The instrumented boxing headgear data were processed to determine linear and rotational acceleration at the head center of gravity, impact location, and impact severity metrics, such as the Head Injury Criterion (HIC) and Gadd Severity Index (GSI). The instrumented boxing headgear was fitted to a Hybrid III (HIII) head form and impacted with a weighted pendulum to characterize accuracy and repeatability. Fifty-six impacts over 3 speeds and 5 locations were used to simulate blows most commonly observed in boxing. A high correlation between the HIII and instrumented boxing headgear was established for peak linear and rotational acceleration (r2= 0.91), HIC (r2 = 0.88), and GSI (r2 = 0.89). Mean location error was 9.7 +/- 5.2 masculine. Based on this study, the IBH is a valid system for measuring head acceleration and impact location that can be integrated into training and competition.

  3. Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: results of the randomized phase I/II ADVANTAGE trial (phase II part)

    National Research Council Canada - National Science Library

    Vermorken, J B; Peyrade, F; Krauss, J; Mesía, R; Remenar, E; Gauler, T C; Keilholz, U; Delord, J P; Schafhausen, P; Erfán, J; Brümmendorf, T H; Iglesias, L; Bethe, U; Hicking, C; Clement, P M

    2014-01-01

    ... αvβ3 and αvβ5 integrins and is investigated as a treatment strategy. The phase I/II study ADVANTAGE evaluated cilengitide combined with cisplatin, 5-fluorouracil, and cetuximab (PFE) in R/M-SCCHN...

  4. Evaluación del impacto de un tratamiento nutricional intensivo sobre el estado nutricional de pacientes con cáncer de cabeza y cuello en estadio III y IV Effect of an intensive nutritional treatment in nutritional status of head and neck cancer patients in stages III and IV

    Directory of Open Access Journals (Sweden)

    V. Fuchs

    2008-04-01

    Full Text Available Objetivo: La desnutrición y la pérdida acelerada de peso son frecuentes en pacientes con cáncer. El cáncer de cabeza y cuello (cáncer de C y C afecta el estado nutricional por la localización y estirpe del tumor. El objetivo fue evaluar el efecto de un tratamiento nutricional intensivo (TNI sobre el estado nutricional en pacientes con cáncer de C y C en estadios avanzados y compararlos con un grupo control histórico cuyo tratamiento nutricional fue el convencional (TC. Métodos: A todos los pacientes se les realizó una evaluación del estado nutricional al ingreso (antropométrica, bioquímica y dietética. Se calculó un plan de alimentación que cubriera su requerimiento individual. En caso de que no fuera posible cubrir sus requerimientos vía oral se colocó una sonda para alimentación enteral. La evaluación del estado nutricional se realizó durante el tratamiento oncológico cada 21 días (cuatro evaluaciones. Los resultados se compararon el grupo del TC (25 pacientes que consistió en orientación alimentaria general. El análisis de resultados se llevó a cabo con la prueba no paramétrica U de Mann Whitney. Resultados: El TNI (28 pacientes se asoció con el mantenimiento del estado nutricional a lo largo del tratamiento oncológico. Los indicadores significativos fueron: cambio de peso 55 a 47 kg en TC contra 59 a 58 kg en TNI (p Objective: Malnutrition and accelerated weight loss are frequent secondary diagnosis in patients with cancer. Head and neck cancer (H & N Cancer affects nutritional status because of the tumor type and localization. The aim of the study was to assess the effect of an intensive nutritional treatment (INT on nutritional status of H & N cancer patients, stages III and IV and to compare that with a historical control whose nutritional treatment was conventional (CT. Methods: All patients were nutritionally assessed before oncological treatment started (anthropometrical, biochemical, and dietetically. A

  5. Physical properties of the human head: mass, center of gravity and moment of inertia.

    Science.gov (United States)

    Yoganandan, Narayan; Pintar, Frank A; Zhang, Jiangyue; Baisden, Jamie L

    2009-06-19

    This paper presents a synthesis of biomedical investigations of the human head with specific reference to certain aspects of physical properties and development of anthropometry data, leading to the advancement of dummies used in crashworthiness research. As a significant majority of the studies have been summarized as reports, an effort has been made to chronologically review the literature with the above objectives. The first part is devoted to early studies wherein the mass, center of gravity (CG), and moment of inertia (MOI) properties are obtained from human cadaver experiments. Unembalmed and preserved whole-body and isolated head and head-neck experiments are discussed. Acknowledging that the current version of the Hybrid III dummy is the most widely used anthropomorphic test device in motor vehicle crashworthiness research for frontal impact applications for over 30 years, bases for the mass and MOI-related data used in the dummy are discussed. Since the development and federalization of the dummy in the United States, description of methods used to arrive at these properties form a part of the manuscript. Studies subsequent to the development of this dummy including those from the US Military are also discussed. As the head and neck are coupled in any impact, and increasing improvements in technology such as advanced airbags, and pre-tensioners and load limiters in manual seatbelts affect the kinetics of the head-neck complex, the manuscript underscores the need to pursue studies to precisely determine all the physical properties of the head. Because the most critical parameters (locations of CG and occipital condyles (OC), mass, and MOI) have not been determined on a specimen-by-specimen basis in any single study, it is important to gather these data in future experiments. These critical data will be of value for improving occupant safety, designing advanced restraint systems, developing second generation dummies, and assessing the injury mitigating

  6. Richard III

    DEFF Research Database (Denmark)

    Lauridsen, Palle Schantz

    2017-01-01

    Kort analyse af Shakespeares Richard III med fokus på, hvordan denne skurk fremstilles, så tilskuere (og læsere) langt henad vejen kan føle sympati med ham. Med paralleller til Netflix-serien "House of Cards"......Kort analyse af Shakespeares Richard III med fokus på, hvordan denne skurk fremstilles, så tilskuere (og læsere) langt henad vejen kan føle sympati med ham. Med paralleller til Netflix-serien "House of Cards"...

  7. Is HEADS in our heads?

    DEFF Research Database (Denmark)

    Boisen, Kirsten A; Hertz, Pernille Grarup; Blix, Charlotte

    2016-01-01

    BACKGROUND: Outpatient clinic visits are a window of opportunity to address health risk behaviors and promote a healthier lifestyle among young people. The HEADS (Home, Education, Eating, Activities, Drugs [i.e. substance use including tobacco, alcohol, and illegal drugs], Sexuality [including...... care professionals participated. We found only small reported differences between staff and young patients regarding whether home, education, and activity were addressed. However, staff reported twice the rate of addressing smoking, alcohol, illegal drugs, sexuality, and contraception compared to young...... patients. Young patients reported that smoking, alcohol, illegal drugs, sexuality, and contraception were addressed significantly more at adult clinics in comparison to pediatric clinics. After controlling for age, gender and duration of illness, according to young patients, adjusted odds ratios...

  8. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... of the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a ... of page What are some common uses of the procedure? CT scanning of the head is typically ...

  9. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... of the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a ... of page What are some common uses of the procedure? CT scanning of the head is typically ...

  10. Validation of CT brain perfusion methods using a realistic dynamic head phantom

    NARCIS (Netherlands)

    Riordan, A.J.; Prokop, M.; Viergever, M.A.; Dankbaar, J.W.; Smit, E.J.; Jong, H.W. de

    2011-01-01

    PURPOSE: Development and evaluation of a realistic hybrid head phantom for the validation of quantitative CT brain perfusion methods. METHODS: A combination, or hybrid, of CT images of an anthropomorphic head phantom together with clinically acquired MRI brain images was used to construct a dynamic

  11. Head Impact Laboratory (HIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The HIL uses testing devices to evaluate vehicle interior energy attenuating (EA) technologies for mitigating head injuries resulting from head impacts during mine/...

  12. Heading and head injuries in soccer.

    Science.gov (United States)

    Kirkendall, D T; Jordan, S E; Garrett, W E

    2001-01-01

    In the world of sports, soccer is unique because of the purposeful use of the unprotected head for controlling and advancing the ball. This skill obviously places the player at risk of head injury and the game does carry some risk. Head injury can be a result of contact of the head with another head (or other body parts), ground, goal post, other unknown objects or even the ball. Such impacts can lead to contusions, fractures, eye injuries, concussions or even, in rare cases, death. Coaches, players, parents and physicians are rightly concerned about the risk of head injury in soccer. Current research shows that selected soccer players have some degree of cognitive dysfunction. It is important to determine the reasons behind such deficits. Purposeful heading has been blamed, but a closer look at the studies that focus on heading has revealed methodological concerns that question the validity of blaming purposeful heading of the ball. The player's history and age (did they play when the ball was leather and could absorb significant amounts of water), alcohol intake, drug intake, learning disabilities, concussion definition and control group use/composition are all factors that cloud the ability to blame purposeful heading. What does seem clear is that a player's history of concussive episodes is a more likely explanation for cognitive deficits. While it is likely that the subconcussive impact of purposeful heading is a doubtful factor in the noted deficits, it is unknown whether multiple subconcussive impacts might have some lingering effects. In addition, it is unknown whether the noted deficits have any affect on daily life. Proper instruction in the technique is critical because if the ball contacts an unprepared head (as in accidental head-ball contacts), the potential for serious injury is possible. To further our understanding of the relationship of heading, head injury and cognitive deficits, we need to: learn more about the actual impact of a ball on the

  13. Hybrid Baryons

    CERN Document Server

    Page, P R

    2003-01-01

    We review the status of hybrid baryons. The only known way to study hybrids rigorously is via excited adiabatic potentials. Hybrids can be modelled by both the bag and flux-tube models. The low-lying hybrid baryon is N 1/2^+ with a mass of 1.5-1.8 GeV. Hybrid baryons can be produced in the glue-rich processes of diffractive gamma N and pi N production, Psi decays and p pbar annihilation.

  14. Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists

    DEFF Research Database (Denmark)

    Madsbad, Sten

    2016-01-01

    weekly, albiglutide once weekly and dulaglutide once weekly. The phase III trial of a seventh GLP-1RA, taspoglutide once weekly, was stopped because of unacceptable adverse events (AEs). Nine phase III head-to-head trials and one large phase II study have compared the efficacy and safety of these seven...... gastric emptying, they have greater effects on postprandial glucose levels than the longer-acting agents, whereas the longer-acting compounds reduced plasma glucose throughout the 24-h period studied. Liraglutide was associated with weight reductions similar to those with exenatide twice daily but greater...

  15. Tomo III

    OpenAIRE

    2015-01-01

    Memorias, histórico, físicas, crítico, apologéticas de la América Meridional con unas breves advertencias y noticias útiles, a los que de orden de Su Majestad, hubiesen de viajar y describir aquellas vastas regiones. Reino Animal. Tomo III. Por un anónimo americano en Cádiz por los años de 1757. Primera Parte Prólogo Artículo 1°De los cuadrúpedos útiles al hombre a varios usos y a su sustento. Vaca Caballos Carneros de la tierra, especie de camellos Vicuña Guanacos Puercos monteses Artículo 2...

  16. Hybrid vehicles

    Energy Technology Data Exchange (ETDEWEB)

    West, J.G.W. [Electrical Machines (United Kingdom)

    1997-07-01

    The reasons for adopting hybrid vehicles result mainly from the lack of adequate range from electric vehicles at an acceptable cost. Hybrids can offer significant improvements in emissions and fuel economy. Series and parallel hybrids are compared. A combination of series and parallel operation would be the ideal. This can be obtained using a planetary gearbox as a power split device allowing a small generator to transfer power to the propulsion motor giving the effect of a CVT. It allows the engine to run at semi-constant speed giving better fuel economy and reduced emissions. Hybrid car developments are described that show the wide range of possible hybrid systems. (author)

  17. Inhibition of HTLV-III by exogenous oligonucleotides

    Energy Technology Data Exchange (ETDEWEB)

    Goodchild, J.; Zamecnik, P.C.

    1989-02-21

    A method is described of detecting the presence of HTLV-III virus in a sample by demonstrating inhibition of replication of the virus in cells which are normally killed by the HTLV-III virus after the cells have been (a) combined with the sample and an oligonucleotide complementary to at least one highly conserved region of the HTLV-III genome necessary for HTLV-III replication and capable of hybridizing with at least the highly conserved region, the highly conserved region of the HTLV-III genome being a nucleotide sequence present in the genomes of HTLV-III isolates and the oligonucleotide complementary to at least one highly conserved region of the HTLV-III genome necessary for HTLV-III replication being complementary to a region of the HTLV-III genome.

  18. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... limitations of CT Scanning of the Head? What is CT Scanning of the Head? Computed tomography, more ... the body being studied. top of page How is the procedure performed? The technologist begins by positioning ...

  19. One-year results of cemented bipolar radial head prostheses for comminuted radial head fractures

    Directory of Open Access Journals (Sweden)

    Laun, Reinhold

    2015-12-01

    Full Text Available Introduction: Comminuted radial head fractures (Mason type III continue to pose a challenge to orthopedic surgeons. When internal fixation is not possible, radial head arthroplasty has been advocated as the treatment of choice. The purpose of this retrospective study was to evaluate clinical and radiological short-term results of patients with Mason type III radial head fractures treated with a cemented bipolar radial prosthesis. Methods: Twelve patients received cemented bipolar radial head hemiarthroplasty for comminuted radial head fractures. In all patients a CT scan was obtained prior to surgical treatment to assess all associated injuries. Postoperatively an early motion protocol was applied. All patients were evaluated clinically and radiologically at an average of 12.7 months.Results: According to the Mayo Modified Wrist Score, the Mayo Elbow Performance Score, the functional rating index of Broberg and Morrey, and the DASH Score good to excellent results were obtained. Grip strength and range of motion were almost at the level of the unaffected contralateral side. Patient satisfaction was high, no instability or signs of loosening of the implant, and only mild signs of osteoarthritis were seen.Conclusion: Overall good to excellent short-term results for primary arthroplasty for comminuted radial head fractures were observed. These encouraging results warrant the conduction of further studies with long-term follow-up and more cases to see if these short-term results can be maintained over time.

  20. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses ... of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive medical ...

  1. Evaluation of Disease Resistance of Head Smut in Particular Corn Germplasms and Hybrids%特用玉米种质及杂交种对丝黑穗病的抗性评价

    Institute of Scientific and Technical Information of China (English)

    郭建国; 郭满库; 郭成; 魏宏玉; 金社林

    2014-01-01

    The disease resistance to Sporisorium reilianum in 131 particular germplasms and 57 particular hybrids was identified when seeds were covered by 0.1% soil carried with teliospores . The results showed that the resistant and susceptible germplasms respectively were 6 antiviral or anti-resistant and 125 susceptible or highly susceptible in 131 particular germplasms, the resistant and susceptible varieties were 8 antiviral or anti-resistant and 49 susceptible or highly susceptible varities in 57 particular hybrids,respectively . The numbered of disease manifestations were 00097153 and 00231081 and moderately resistant germplasms were 00030253、00097112、00201242 and 00211465 which importantly resistant resources in sweet and waxy corn varieties breeding in the future. The diesease-resistant hybrids Gaoyou 1 and moderately resistant hybrids Baizaonuo、Jingkenuo 120、Xingnuo 918、Huatiannian 83、Duntian 2、Tiandan 22 and Gaoyou 115 were importantly commercial varieties in sweet,waxy and high oil corn in the future .%采用菌土覆盖接种法,鉴定评价了131个玉米特用种质和57个特用杂交种对丝黑穗病的抗病性。结果表明,131份特用种质中,6份表现抗病或中抗,125份表现感病或高感;57个特用杂交种中,8个品种表现抗病或中抗,49个品种表现感病或高感。表现抗病的编号为00097153、00231081的抗病种质和编号为00030253、00097112、00201242、00211465的中抗种质可作为甜糯品种选育的重要抗源;抗病杂交种高优1号和中抗杂交种白早糯、京科糯120、星糯918、华甜粘83、敦甜2号、甜单22号、高油115可作为甜糯和高油玉米的主推广品种。

  2. Mechanistic insights into type III restriction enzymes.

    Science.gov (United States)

    Raghavendra, Nidhanapati K; Bheemanaik, Shivakumara; Rao, Desirazu N

    2012-01-01

    Type III restriction-modification (R-M) enzymes need to interact with two separate unmethylated DNA sequences in indirectly repeated, head-to-head orientations for efficient cleavage to occur at a defined location next to only one of the two sites. However, cleavage of sites that are not in head-to-head orientation have been observed to occur under certain reaction conditions in vitro. ATP hydrolysis is required for the long-distance communication between the sites prior to cleavage. Type III R-M enzymes comprise two subunits, Res and Mod that form a homodimeric Mod2 and a heterotetrameric Res2Mod2 complex. The Mod subunit in M2 or R2M2 complex recognizes and methylates DNA while the Res subunit in R2M2 complex is responsible for ATP hydrolysis, DNA translocation and cleavage. A vast majority of biochemical studies on Type III R-M enzymes have been undertaken using two closely related enzymes, EcoP1I and EcoP15I. Divergent opinions about how the long-distance interaction between the recognition sites exist and at least three mechanistic models based on 1D- diffusion and/or 3D- DNA looping have been proposed.

  3. Origin of Theater-headed Tributaries to Escalante and Glen Canyons, Utah

    Science.gov (United States)

    Irwin, R. P.; Fortezzo, C. M.; Tooth, S. E.; Howard, A. D.; Zimbelman, J. R.; Barnhart, C. J.; Benthem, A. J.; Brown, C. C.; Parsons, R. A.

    2009-03-01

    Theater-headed tributaries to Glen Canyon, Utah, are important analogs to martian valley networks. Our field study suggests a hybrid model involving seepage weathering of Navajo sandstone, sheet fracturing, and transport of debris by flash floods.

  4. 肿瘤表面刮片行第二代杂交捕获试验检测头颈部肿瘤人乳头状瘤病毒(HPV)感染分析%Detection of Human Papillomavirus in Head and Neck Carcinoma by Hybrid Capture II

    Institute of Scientific and Technical Information of China (English)

    陈雪松; 李素艳; 高黎; 易俊林; 罗京伟; 徐国镇; 黄晓东; 曲媛; 张世平; 肖建平

    2012-01-01

    To analyze the detection of Human Papillomavims (HPV) in head and neck carcinoma by Hybrid Capture II ( HC-Ⅱ) . Methods: From Jan. 2010 to Junn. 2011,139 patients with histologically proven head and neck cancer were treated in the radiotherapy department of our hospital. Specimens were collected from these study subjects with a conical cytology brush, and Human Papillomavims (HPV) were detected by Hybrid Capture II (HC-Ⅱ ) . Results; Of the 139 cases, there were 22 cases of oropha-ryngeal cancer and hypopharyngeal carcinoma, 107 cases of nasopharyngeal carcinoma(NPC) ,2 cases of oral cancer, 2 cases of laryn-gocarcinoma and 6 cases of other malignancies. HPV was positive in 14 cases with the HPV-positive rate was 10. 1% . The expression rate of HPV in OPC and hypopharyngeal carcinoma, NPC was 22.7% (5 cases) and 7. 5% (8 cases) , respectively. HPV-16 positive rate was 44% in the HPV-positive patients. Conclusions; It is feasible to detect the HPV infection by using Hybrid Capture test (HC-Ⅱ ) technique for head and neck carcinoma. HPV infection may be one of the main pathogenic risk factors for pharyngeal cancer, espe-cially for OPC.The relation between HPV and NPC's etiology needs to be further confirmed.%目的 分析使用肿瘤表面刮片技术检测头颈部肿瘤患者人乳头状瘤病毒(HPV)感染结果.方法:2010年1月至2011年6月间,在我院头颈放疗科就诊的经病理证实的头颈部肿瘤患者139例,采用肿瘤表面刮片第二代杂交捕获试验(HC-II)技术分析测定HPV感染.结果:139例头颈部肿瘤患者中口咽癌及下咽癌22例,鼻咽癌107例,口腔癌2例,喉癌2例,其他恶性肿瘤6例.139例头颈部肿瘤组织中HPV感染共14例,感染率为10.1%.口咽及下咽癌、鼻咽癌患者HPV感染分别为5例(22.7%)、8例(7.5%).HPV感染者中HPV-16型感染占44%.结论 头颈部肿瘤使用肿瘤表面刮片第二代杂交捕获试验(HC-II)技术进行HPV检测有可行性,HPV感染可能是咽部肿瘤

  5. Head and Neck

    DEFF Research Database (Denmark)

    Højgaard, Liselotte; Berthelsen, Anne Kiil; Loft, Annika

    2014-01-01

    Positron emission tomography (PET)/computed tomography with FDG of the head and neck region is mainly used for the diagnosis of head and neck cancer, for staging, treatment evaluation, relapse, and planning of surgery and radio therapy. This article is a practical guide of imaging techniques......, including a detailed protocol for FDG PET in head and neck imaging, physiologic findings, and pitfalls in selected case stories....

  6. Laboratory Validation of Two Wearable Sensor Systems for Measuring Head Impact Severity in Football Players.

    Science.gov (United States)

    Siegmund, Gunter P; Guskiewicz, Kevin M; Marshall, Stephen W; DeMarco, Alyssa L; Bonin, Stephanie J

    2016-04-01

    Wearable sensors can measure head impact frequency and magnitude in football players. Our goal was to quantify the impact detection rate and validity of the direction and peak kinematics of two wearable sensors: a helmet system (HITS) and a mouthguard system (X2). Using a linear impactor, modified Hybrid-III headform and one helmet model, we conducted 16 impacts for each system at 12 helmet sites and 5 speeds (3.6-11.2 m/s) (N = 896 tests). Peak linear and angular accelerations (PLA, PAA), head injury criteria (HIC) and impact directions from each device were compared to reference sensors in the headform. Both sensors detected ~96% of impacts. Median angular errors for impact directions were 34° for HITS and 16° for X2. PLA, PAA and HIC were simultaneously valid at 2 sites for HITS (side, oblique) and one site for X2 (side). At least one kinematic parameter was valid at 2 and 7 other sites for HITS and X2 respectively. Median relative errors for PLA were 7% for HITS and -7% for X2. Although sensor validity may differ for other helmets and headforms, our analyses show that data generated by these two sensors need careful interpretation.

  7. Hyperfractionated Accelerated Radiation Therapy (HART) of 70.6 Gy With Concurrent 5-FU/Mitomycin C Is Superior to HART of 77.6 Gy Alone in Locally Advanced Head and Neck Cancer: Long-term Results of the ARO 95-06 Randomized Phase III Trial

    Energy Technology Data Exchange (ETDEWEB)

    Budach, Volker, E-mail: volker.budach@charite.de [Department of Radiation Oncology, Charité Universitätsmedizin Berlin (Germany); Stromberger, Carmen [Department of Radiation Oncology, Charité Universitätsmedizin Berlin (Germany); Poettgen, Christoph [Department of Radiation Oncology, University Hospital of Essen (Germany); Baumann, Michael [Department of Radiation Oncology, University Hospital of Dresden (Germany); Budach, Wilfried [Department of Radiation Oncology, Heinrich Heine Universität Düsseldorf (Germany); Grabenbauer, Gerhard [Department of Radiation Oncology, University Hospitals of Erlangen (Germany); Marnitz, Simone [Department of Radiation Oncology, Charité Universitätsmedizin Berlin (Germany); Olze, Heidi [Department of Head and Neck Surgery, Charité Universitätsmedizin Berlin (Germany); Wernecke, Klaus-Dieter [Sostana GmbH, Berlin (Germany); Ghadjar, Pirus [Department of Radiation Oncology, Charité Universitätsmedizin Berlin (Germany)

    2015-04-01

    Purpose: To report the long-term results of the ARO 95-06 randomized trial comparing hyperfractionated accelerated chemoradiation with mitomycin C/5-fluorouracil (C-HART) with hyperfractionated accelerated radiation therapy (HART) alone in locally advanced head and neck cancer. Patients and Methods: The primary endpoint was locoregional control (LRC). Three hundred eighty-four patients with stage III (6%) and IV (94%) oropharyngeal (59.4%), hypopharyngeal (32.3%), and oral cavity (8.3%) cancer were randomly assigned to 30 Gy/2 Gy daily followed by twice-daily 1.4 Gy to a total of 70.6 Gy concurrently with mitomycin C/5-FU (C-HART) or 16 Gy/2 Gy daily followed by twice-daily 1.4 Gy to a total dose of 77.6 Gy alone (HART). Statistical analyses were done with the log-rank test and univariate and multivariate Cox regression analyses. Results: The median follow-up time was 8.7 years (95% confidence interval [CI]: 7.8-9.7 years). At 10 years, the LRC rates were 38.0% (C-HART) versus 26.0% (HART, P=.002). The cancer-specific survival and overall survival rates were 39% and 10% (C-HART) versus 30.0% and 9% (HART, P=.042 and P=.049), respectively. According to multivariate Cox regression analysis, the combined treatment was associated with improved LRC (hazard ratio [HR]: 0.6 [95% CI: 0.5-0.8; P=.002]). The association between combined treatment arm and increased LRC appeared to be limited to oropharyngeal cancer (P=.003) as compared with hypopharyngeal or oral cavity cancer (P=.264). Conclusions: C-HART remains superior to HART in terms of LRC. However, this effect may be limited to oropharyngeal cancer patients.

  8. The hybrid BCI

    Directory of Open Access Journals (Sweden)

    Gert Pfurtscheller

    2010-04-01

    Full Text Available Nowadays, everybody knows what a hybrid car is. A hybrid car normally has 2 engines, its main purpose being to enhance energy efficiency and reduce CO2 output. Similarly, a typical hybrid brain-computer interface (BCI is also composed of 2 BCIs or at least one BCI and another system. Such a hybrid BCI, like any BCI, must fulfil the following four criteria: (i the device must rely on signals recorded directly from the brain; (ii there must be at least one recordable brain signal that the user can intentionally modulate to effect goal-directed behaviour; (iii real time processing; and (iv the user must obtain feedback. This paper introduces some hybrid BCIs which have already been published or are currently in development or validation, and some concepts for future work. The BCIs described classify 2 EEG patterns: One is the event-related (desynchronisation (ERD, ERS of sensorimotor rhythms, and the other is the steady-state visual evoked potential (SSVEP. The hybrid BCI can either have more than one input whereby the inputs are typically processed simultaneously or operate 2 systems sequentially, whereby the first system can act as a “brain switch”. In the case of self-paced operation of a SSVEP-based hand orthosis control with an motor imagery-based switch it was possible to reduce the rate of false positives during resting periods by about 50% compared to the SSVEP BCI alone. It is shown that such a brain switch can also rely on hemodynamic changes measured through near-infrared spectroscopy (NIRS. Another interesting approach is a hybrid BCI with simultaneous operations of ERD- and SSVEP-based BCIs. Here it is important to prove the existing promising offline simulation results with online experiments. Hybrid BCIs can also use one brain signal and another input. Such an additional input can be a physiological signal like the heart rate but also a signal from an external device like, an eye gaze control system.

  9. The formation of improved tetraploid population of red crucian carp x common carp hybrids by androgenesis.

    Science.gov (United States)

    Duan, Wei; Qin, QinBo; Chen, Song; Liu, ShaoJun; Wang, Jing; Zhang, Chun; Sun, YuanDong; Liu, Yun

    2007-12-01

    Bisexual fertile diploid androgenetic individuals (A(0)) (2n=100) were formed by androgenesis. In this way, the diploid spermatozoa from male allotetraploid hybrids (AT) (4n=200) of red crucian carp (Carassius auratus red var.) (female) x common carp (Cyprinus carpio L.) (male) were used to fertilize the UV-treated haploid eggs of goldfish (Carassius auratus), and living androgenetic diploid fish were developed. The A(0) became sexually mature at the age of 2 years, and they fertilized with each other to form their offspring (A(1)). In this study, we observed the chromosomal number, gonadal structure and appearance of A(1) fish. The results are as follows: (1) In A(1), there were 85% tetraploids (A(1)-4n), 10% triploids (A(1)-3n) and 5% diploids (A(1)-2n), suggesting that diploid A(0) could produce diploid gametes. It was concluded that the formation of diploid gametes generated from diploid A(0) was probably related to the mechanism of pre-meiotic endoreduplication. (2) Among A(1), only A(1)-4n possessed normal ovaries and testes. The mature males of A1-4n produced white semen. Under the electron microscope, the head of diploid sperm generated by A(1)-4n was bigger than that of haploid sperm generated by red crucian carp. In the testes of the A(1)-4n, there were many mature normal spermatozoa with a head bearing plasma membrane and a tail having the typical structure of "9+2" microtubules. Between the head and the tail, there were some mitochondria. The ovaries of A(1)-4n developed well and mainly contained II, III and IV-stage oocytes. The IV-stage oocytes were surrounded by inner and outer follicular cells. The micropyle was observed on the oolemma of follicular cells. There were abundant yolks and plenty of endoplasmic reticulum in the cytoplasm of IV-stage oocytes. Because A(1)-2n and A(1)-3n were distant crossing diploid hybrids and triploid hybrids respectively, they possessed abnormal gonads, and no mature semen and eggs were observed. (3) Compared with

  10. Hybrid Metaheuristics

    CERN Document Server

    2013-01-01

    The main goal of this book is to provide a state of the art of hybrid metaheuristics. The book provides a complete background that enables readers to design and implement hybrid metaheuristics to solve complex optimization problems (continuous/discrete, mono-objective/multi-objective, optimization under uncertainty) in a diverse range of application domains. Readers learn to solve large scale problems quickly and efficiently combining metaheuristics with complementary metaheuristics, mathematical programming, constraint programming and machine learning. Numerous real-world examples of problems and solutions demonstrate how hybrid metaheuristics are applied in such fields as networks, logistics and transportation, bio-medical, engineering design, scheduling.

  11. Measurement of six degrees of freedom head kinematics in impact conditions employing six accelerometers and three angular rate sensors (6aω configuration).

    Science.gov (United States)

    Kang, Yun-Seok; Moorhouse, Kevin; Bolte, John H

    2011-11-01

    The ability to measure six degrees of freedom (6 DOF) head kinematics in motor vehicle crash conditions is important for assessing head-neck loads as well as brain injuries. A method for obtaining accurate 6 DOF head kinematics in short duration impact conditions is proposed and validated in this study. The proposed methodology utilizes six accelerometers and three angular rate sensors (6aω configuration) such that an algebraic equation is used to determine angular acceleration with respect to the body-fixed coordinate system, and angular velocity is measured directly rather than numerically integrating the angular acceleration. Head impact tests to validate the method were conducted using the internal nine accelerometer head of the Hybrid III dummy and the proposed 6aω scheme in both low (2.3 m/s) and high (4.0 m/s) speed impact conditions. The 6aω method was compared with a nine accelerometer array sensor package (NAP) as well as a configuration of three accelerometers and three angular rate sensors (3aω), both of which have been commonly used to measure 6 DOF kinematics of the head for assessment of brain and neck injuries. The ability of each of the three methods (6aω, 3aω, and NAP) to accurately measure 6 DOF head kinematics was quantified by calculating the normalized root mean squared deviation (NRMSD), which provides an average percent error over time. Results from the head impact tests indicate that the proposed 6aω scheme is capable of producing angular accelerations and linear accelerations transformed to a remote location that are comparable to that determined from the NAP scheme in both low and high speed impact conditions. The 3aω scheme was found to be unable to provide accurate angular accelerations or linear accelerations transformed to a remote location in the high speed head impact condition due to the required numerical differentiation. Both the 6aω and 3aω schemes were capable of measuring accurate angular displacement while the

  12. Head Injuries in Children

    Science.gov (United States)

    Pennington, Nicole

    2010-01-01

    School nurses play a crucial role in injury prevention and initial treatment when injuries occur at school. The role of school nurses includes being knowledgeable about the management of head injuries, including assessment and initial treatment. The school nurse must be familiar with the outcomes of a head injury and know when further evaluation…

  13. Open reduction and internal fixation of radial head fractures.

    Science.gov (United States)

    Iacobellis, C; Visentin, A; Aldegheri, R

    2012-05-01

    This study examines 32 patients operated for radial head fractures, mean age 48.7 years (range 26-76 years), Mason type II in 25 cases and Mason type III with 3 main fragments in 7 cases. Fractures were surgically reduced and fixed with Herbert's (12 cases) or Osteomed (20 cases) cannulated screws. The latter have a head that is prono-supination. In addition, suturing of the annular ligament and the joint capsule is made easier by the reduced invasiveness of screws. Screw treatment is effective in non-comminuted fractures of the radial head.

  14. Hybrid Swarm Intelligence Energy Efficient Clustered Routing Algorithm for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Rajeev Kumar

    2016-01-01

    Full Text Available Currently, wireless sensor networks (WSNs are used in many applications, namely, environment monitoring, disaster management, industrial automation, and medical electronics. Sensor nodes carry many limitations like low battery life, small memory space, and limited computing capability. To create a wireless sensor network more energy efficient, swarm intelligence technique has been applied to resolve many optimization issues in WSNs. In many existing clustering techniques an artificial bee colony (ABC algorithm is utilized to collect information from the field periodically. Nevertheless, in the event based applications, an ant colony optimization (ACO is a good solution to enhance the network lifespan. In this paper, we combine both algorithms (i.e., ABC and ACO and propose a new hybrid ABCACO algorithm to solve a Nondeterministic Polynomial (NP hard and finite problem of WSNs. ABCACO algorithm is divided into three main parts: (i selection of optimal number of subregions and further subregion parts, (ii cluster head selection using ABC algorithm, and (iii efficient data transmission using ACO algorithm. We use a hierarchical clustering technique for data transmission; the data is transmitted from member nodes to the subcluster heads and then from subcluster heads to the elected cluster heads based on some threshold value. Cluster heads use an ACO algorithm to discover the best route for data transmission to the base station (BS. The proposed approach is very useful in designing the framework for forest fire detection and monitoring. The simulation results show that the ABCACO algorithm enhances the stability period by 60% and also improves the goodput by 31% against LEACH and WSNCABC, respectively.

  15. Crystal structure of the new hybrid material bis-(1,4-diazo-niabi-cyclo-[2.2.2]octa-ne) di-μ-chlorido-bis-[tetra-chlorido-bis-muthate(III)] dihydrate.

    Science.gov (United States)

    Chouri, Marwen; Boughzala, Habib

    2015-11-01

    The title compound bis-(1,4-diazo-niabi-cyclo-[2.2.2]octa-ne) di-μ-chlorido-bis-[tetra-chlorido-bis-muthate(III)] dihydrate, (C6H14N2)2[Bi2Cl10]·2H2O, was ob-tain-ed by slow evaporation at room temperature of a hydro-chloric aqueous solution (pH = 1) containing bis-muth(III) nitrate and 1,4-di-aza-bicyclo-[2.2.2]octane (DABCO) in a 1:2 molar ratio. The structure displays a two-dimensional arrangement parallel to (100) of isolated [Bi2Cl10](4-) bi-octa-hedra (site symmetry -1) separated by layers of organic 1,4-diazo-niabi-cyclo-[2.2.2]octane dications [(DABCOH2)(2+)] and water mol-ecules. O-H⋯Cl, N-H⋯O and N-H⋯Cl hydrogen bonds lead to additional cohesion of the structure.

  16. Hybrid intermediaries

    OpenAIRE

    Cetorelli, Nicola

    2014-01-01

    I introduce the concept of hybrid intermediaries: financial conglomerates that control a multiplicity of entity types active in the "assembly line" process of modern financial intermediation, a system that has become known as shadow banking. The complex bank holding companies of today are the best example of hybrid intermediaries, but I argue that financial firms from the "nonbank" space can just as easily evolve into conglomerates with similar organizational structure, thus acquiring the cap...

  17. Hybrid composites

    CSIR Research Space (South Africa)

    Jacob John, Maya

    2009-04-01

    Full Text Available effect was observed for the elongation at break of the hybrid composites. The impact strength of the hybrid composites increased with the addition of glass fibres. The tensile and impact properties of thermoplastic natural rubber reinforced short... panels made from conventional structural materials. Figure 3 illustrates the performance of cellular biocomposite panels against conventional systems used for building and residential construction, namely a pre- cast pre-stressed hollow core concrete...

  18. Human lymphocyte markers defined by antibodies derived from somatic cell hybrids. III. A marker defining a subpopulation of lymphocytes which cuts across the normal T-B-null classification.

    Science.gov (United States)

    Zola, H; Beckman, I G; Bradley, J; Brooks, D A; Kupa, A; McNamara, P J; Smart, I J; Thomas, M E

    1980-06-01

    A somatic cell hybrid line which secreted antibody reacting selectively with a proportion of the white cells in human blood was prepared. The hybridoma appeared to be monoclonal, and the antibody secreted stained 67% of the lymphocyte population in blood. It reacted less well with granulocytes and monocytes. The lymphocytes stained comprised 80% of the T cells and 50% of the B cells. The antibody showed no recognizable pattern in its reactivity with cell lines and leukaemic cells, although B cells tended to react less well than T cells, null cells, or myeloid leukaemic cells. The expression of the antigenic determinant is discussed in relation to the classification of leucocytes. This determinant and certain other markers exhibited differential expression on closely related cells, and yet were shared by more distantly related cells.

  19. Comparison of Natural Head Position in Different Anteroposterior Malocclusions

    Science.gov (United States)

    Hedayati, Zohreh; Paknahad, Maryam; Zorriasatine, Farbod

    2013-01-01

    Objective: The facial esthetics after orthodontic treatment and orthognathic surgery may be affected by the patient’s natural head position. The purpose of this study was to evaluate the natural head position for the three skeletal classes of malocclusion. Materials and Methods: Our sample consisted of 102 lateral cephalometric radiographs of patients aged 15 to 18 years; class I (n=32), class II (n=40) and class III (n=30). Nine landmarks of the craniofacial skeleton and three landmarks of the cervical vertebrae were determined. Variables consisted of two angles for cervical posture (OPT/Hor and CVT/Hor), three angles for craniofacial posture (SN/Ver, PNS-ANS/Ver, and ML/Ver ) and five for craniofacial angulation (SN/OPT, SN/CVT, PNS-ANS/OPT, PNS-ANS/CVT, ML/CVT). The data were analyzed statistically using ANOVA and post hoc tests. Results: PNS-ANS/Ver and SN/Ver differed significantly (p<0.05) among the three groups. There were no significant differences between class I and class II malocclusions for the indicator angles of cranial posture except for ML/Ver. The SN/CVT was significantly different for class I compared to class III patients. A head posture camouflaging the underlying skeletal class III was observed in our population. Conclusion: A more forward head posture was observed in skeletal class III participants compared to skeletal class I and II and that class III patients tended to incline their head more ventral compared to class I participants. These findings may have implications for the amount of jaw movements during surgery particularly in patients with a class III malocclusion. PMID:25512747

  20. Comparison of Natural Head Position in Different Anteroposterior Malocclusions

    Directory of Open Access Journals (Sweden)

    Zohreh Hedayati

    2013-01-01

    Full Text Available Objective: The facial esthetics after orthodontic treatment and orthognathic surgery may be affected by the patient’s natural head position. The purpose of this study was to evaluate the natural head position for the three skeletal classes of malocclusion.Materials and Methods: Our sample consisted of 102 lateral cephalometric radiographs of patients aged 15 to 18 years; class I (n=32, class II (n=40 and class III (n=30. Nine landmarks of the craniofacial skeleton and three landmarks of the cervical vertebrae were determined. Variables consisted of two angles for cervical posture (OPT/Hor and CVT/Hor, three angles for craniofacial posture (SN/Ver, PNS-ANS/Ver, and ML/Ver and five for craniofacial angulation (SN/OPT, SN/CVT, PNS-ANS/OPT, PNS-ANS/CVT, ML/CVT. The data were analyzed statistically using ANOVA and post hoc tests.Results: PNS-ANS/Ver and SN/Ver differed significantly (p<0.05 among the three groups. There were no significant differences between class I and class II malocclusions for the indicator angles of cranial posture except for ML/Ver. The SN/CVT was significantly different for class I compared to class III patients. A head posture camouflaging the underlying skeletal class III was observed in our population.Conclusion: A more forward head posture was observed in skeletal class III participants compared to skeletal class I and II and that class III patients tended to incline their head more ventral compared to class I participants. These findings may have implications for the amount of jaw movements during surgery particularly in patients with a class III malocclusion

  1. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive ... of page What are some common uses of the procedure? MR imaging of the head is performed ...

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive ... of page What are some common uses of the procedure? MR imaging of the head is performed ...

  3. Ulnar head replacement.

    Science.gov (United States)

    Herbert, Timothy J; van Schoonhoven, Joerg

    2007-03-01

    Recent years have seen an increasing awareness of the anatomical and biomechanical significance of the distal radioulnar joint (DRUJ). With this has come a more critical approach to surgical management of DRUJ disorders and a realization that all forms of "excision arthroplasty" can only restore forearm rotation at the expense of forearm stability. This, in turn, has led to renewed interest in prosthetic replacement of the ulnar head, a procedure that had previously fallen into disrepute because of material failures with early implants, in particular, the Swanson silicone ulnar head replacement. In response to these early failures, a new prosthesis was developed in the early 1990s, using materials designed to withstand the loads across the DRUJ associated with normal functional use of the upper limb. Released onto the market in 1995 (Herbert ulnar head prosthesis), clinical experience during the last 10 years has shown that this prosthesis is able to restore forearm function after ulnar head excision and that the materials (ceramic head and noncemented titanium stem), even with normal use of the limb, are showing no signs of failure in the medium to long term. As experience with the use of an ulnar head prosthesis grows, so does its acceptance as a viable and attractive alternative to more traditional operations, such as the Darrach and Sauve-Kapandji procedures. This article discusses the current indications and contraindications for ulnar head replacement and details the surgical procedure, rehabilitation, and likely outcomes.

  4. Maneuvering impact boring head

    Science.gov (United States)

    Zollinger, W. Thor; Reutzel, Edward W.

    1998-01-01

    An impact boring head may comprise a main body having an internal cavity with a front end and a rear end. A striker having a head end and a tail end is slidably mounted in the internal cavity of the main body so that the striker can be reciprocated between a forward position and an aft position in response to hydraulic pressure. A compressible gas contained in the internal cavity between the head end of the striker and the front end of the internal cavity returns the striker to the aft position upon removal of the hydraulic pressure.

  5. A new experimental hybrid of cabbage suitable for early production

    Directory of Open Access Journals (Sweden)

    Červenski Janko

    2012-01-01

    Full Text Available The paper analyzes experimental hybrids of early cabbage developed at the Institute of Field and Vegetable Crops in the previous period. The hybrids were tested together for two years and then one (H17 was chosen and submitted to the Variety Commission of the Republic of Serbia. In 2011, the experimental hybrid H17 was officially released as an early cabbage hybrid and registered under the name of NS Mendo F1. The hybrid had been developed by crossing two early lines, one of which was sterile. It is characterized by a short growing season - 65 days from transplanting to harvest. The head weight ranges from 2.5 to 3.5 kg depending on the cultural practice applied. The head is light green in color, sweet-tasting, and suitable for fresh consumption. The hybrid’s traits that contributed significantly to the formation of the first principal component were in fact those that the breeders attach most importance to in their breeding programs. These are the traits that directly influence the market value of a new hybrid and make a given hybrid recognizable on the market. Most notable among such traits are head weight and the weight of the useful part of the head.[Projekat Ministarstva nauke Republike Srbije, br. TR 31030

  6. Early Head Start Evaluation

    Data.gov (United States)

    U.S. Department of Health & Human Services — Longitudinal information from an evaluation where children were randomly assigned to Early Head Start or community services as usual;direct assessments and...

  7. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... you! Do you have a personal story about radiology? Share your patient story here Images × Image Gallery ... Pregnancy Head and Neck Cancer X-ray, Interventional Radiology and Nuclear Medicine Radiation Safety Images related to ...

  8. Head and face reconstruction

    Science.gov (United States)

    ... work together. Head and neck surgeons also perform craniofacial reconstruction operations. The surgery is done while you are deep asleep and pain-free (under general anesthesia ). The surgery may take ...

  9. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... headaches, dizziness, and other symptoms of aneurysm, bleeding, stroke and brain tumors. It also helps your doctor ... scanning provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than regular ...

  10. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... a stroke, especially with a new technique called Perfusion CT. brain tumors. enlarged brain cavities (ventricles) in ... X-Ray and CT Exams Blood Clots CT Perfusion of the Head CT Angiography (CTA) Stroke Brain ...

  11. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... traditional x-rays, particularly of soft tissues and blood vessels. CT scanning provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than ...

  12. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... special x-ray equipment to help assess head injuries, severe headaches, dizziness, and other symptoms of aneurysm, ... cancer. In emergency cases, it can reveal internal injuries and bleeding quickly enough to help save lives. ...

  13. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... headaches, dizziness, and other symptoms of aneurysm, bleeding, stroke and brain tumors. It also helps your doctor ... scanning provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than regular ...

  14. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... images of internal organs, bones, soft tissue and blood vessels provide greater detail than traditional x-rays, particularly of soft tissues and blood vessels. CT scanning provides more detailed information on head ...

  15. Head CT scan

    Science.gov (United States)

    Brain CT; Cranial CT; CT scan - skull; CT scan - head; CT scan - orbits; CT scan - sinuses; Computed tomography - cranial; CAT scan - brain ... hold your breath for short periods. A complete scan usually take only 30 seconds to a few ...

  16. Head Start Impact Study

    Data.gov (United States)

    U.S. Department of Health & Human Services — Nationally representative, longitudinal information from an evaluation where children were randomly assigned to Head Start or community services as usual;direct...

  17. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... special x-ray equipment to help assess head injuries, severe headaches, dizziness, and other symptoms of aneurysm, ... cancer. In emergency cases, it can reveal internal injuries and bleeding quickly enough to help save lives. ...

  18. CyberStorm III

    NARCIS (Netherlands)

    Luiijf, H.A.M.; et al

    2010-01-01

    Projectteam Cyber Storm III - De Verenigde Staten organiseerden de afgelopen jaren een reeks grootschalige ICT-crisisoefeningen met de naam Cyber Storm. Cyber Storm III is de derde oefening in de reeks. Het scenario van Cyber Storm III staat in het teken van grootschalige ICT-verstoringen, waarbij n

  19. Head and neck teratomas

    OpenAIRE

    Shah, Ajaz; Latoo, Suhail; Ahmed, Irshad; Malik, Altaf H

    2009-01-01

    Teratomas are complex lesions composed of diverse tissues from all 3 germinal cell layers and may exhibit variable levels of maturity. Head and neck teratomas are most commonly cervical with the oropharynx (epignathus) being the second commonest location. In this article, clinical presentation, behaviour and associated significance of head and neck teratomas have been highlightened. Because of their obscure origin, bizarre microscopic appearance, unpredictable behaviour and often dramatic cli...

  20. Hybrid molecular materials based upon organic pi-electron donors and inorganic metal complexes. Conducting salts of bis(ethylenediseleno)tetrathiafulvalene (BEST) with the octahedral anions hexacyanoferrate(III) and nitroprusside

    CERN Document Server

    Clemente-Leon, M; Galan-Mascaros, J R; Giménez-Saiz, C; Gómez-García, C J; Fabre, J M; Mousdis, G A; Papavassiliou, G C

    2002-01-01

    The synthesis, structure and physical characterization of three new radical salts formed by the organic donor bis(ethylenediseleno)tetrathiafulvalene (BEDS-TTF or BEST) and the paramagnetic hexacyanoferrate(III) anion [Fe(CN) sub 6] sup 3 sup - or the photochromic nitroprusside anion [Fe(CN) sub 5 NO] sup 2 sup - are reported: (BEST) sub 4 [Fe(CN) sub 6] (1), (BEST) sub 3 [Fe(CN) sub 6] sub 2 centre dot H sub 2 O (2) and (BEST) sub 2 [Fe(CN) sub 5 NO] (3). Salts 1 and 3 show a layered structure with alternating organic (beta-type packing) and inorganic slabs. Salt 2 shows an original interpenetrated structure probably due to the unprecedented presence of (BEST) sup 2 sup + dications. The three salts are semiconductors although salt 1 exhibits a high room temperature conductivity and a semiconducting-semiconducting transition at ca. 150 K which has been attributed to a dimerization in the organic sublattice.

  1. Global Positioning System III (GPS III)

    Science.gov (United States)

    2015-12-01

    Military Operations in Urban Terrain; Defense-Wide Mission Support; Air Mobility; and Space Launch Orbital Support. For military users, the GPS III...program provides Precise Positioning Service (PPS) to military operations and force enhancement. It also provides increased anti-jam power to the earth ...to be modified . On January 31, 2016, USD(AT&L) signed the GPS III revised APB. This Change 1 to the APB was due to both cost and schedule breaches

  2. Widely tunable Vernier ring laser on hybrid silicon.

    Science.gov (United States)

    Hulme, J C; Doylend, J K; Bowers, J E

    2013-08-26

    A hybrid silicon tunable Vernier ring laser is designed and fabricated by integration of two intra-cavity ring resonators, hybrid III-V-on-silicon gain elements, and resistive heaters for thermal tuning. Thermal tuning of more than 40 nm is demonstrated with side mode suppression ratio greater than 35 dB and linewidth of 338 kHz.

  3. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head ... limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is ...

  4. Missouri: Early Head Start Initiative

    Science.gov (United States)

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Missouri's Early Head Start/Child Care Partnership Project expands access to Early Head Start (EHS) services for children birth to age 3 by developing partnerships between federal Head Start, EHS contractors, and child care providers. Head Start and EHS contractors that participate in the initiative provide services through community child care…

  5. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses a powerful ... the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that ...

  6. Automation Comparison Procedure for Verification of Hybrid Systems.

    Science.gov (United States)

    1997-11-01

    Lecture Notes in Computer Science vol. 999, Springer-Verlag, (1995). [2] Bowler, 0., Grotzky, J., Nielson, M., Nilson.S., and Van Buren, J...Remmel, J.B., "Feedback Derivations: Near Optimal Controls for Hybrid Systems", to appear in Hybrid Systems III, Springer Lecture Notes in Computer Science . [6...Grossman, R.L., Nerode, A., Ravn, A. and Rischel, H. eds., Hybrid Systems, Lecture Notes in Computer

  7. Economics of head injuries

    Directory of Open Access Journals (Sweden)

    Singh Manmohan

    2006-01-01

    Full Text Available Summary: Head injuries account for significant proportion of neurosurgical admissions and bed occupancy. Patients with head injuries also consume significant proportions of neurosurgical resources. A prospective 6-month study has been carried out to evaluate the expenditure incurred on head injury patients in a modern neurosurgical center equipped with state of the art infrastructure. Costing areas included wages / salaries of health care personnel, cost of medicines / surgical items / crystalloids, general store items, stationary, all investigation charges, equipment cost, overhead building cost, maintenance cost, electricity and water charges and cost of medical gases, air conditioning and operation theatre expenses. Expenditure in each area was calculated and apportioned to each bed. The statistical analysis was done using X2 test. The cost of stay in ward was found to be Rs. 1062 / bed / day and in neurosurgical ICU Rs. 3082 / bed / day. The operation theatre cost for each surgery was Rs. 11948. The cost of hospital stay per day for minor, moderate and severe head injury group was found to be Rs. 1921, Rs. 2569 and Rs. 2713 respectively. The patients who developed complications, the cost of stay per day in the hospital were Rs. 2867. In the operative group, the cost of hospital stay per day was Rs. 3804. The total expenditure in minor head injury was Rs. 7800 per patient, in moderate head injury was Rs. 22172 per patient, whereas in severe head injury, it was found to be Rs. 32852 per patient. Patients who underwent surgery, the total cost incurred was Rs. 33100 per operated patient.

  8. Control approach for comfortable power shifting in hybrid transmissions - ML 450 hybrid

    Energy Technology Data Exchange (ETDEWEB)

    Saenger Zetina, Siegfried; Neiss, Konstantin [Daimler AG, Hybrid Development Center, Troy, MI (United States)

    2008-07-01

    The comfortable shifting control in a luxury class vehicle is extremely important, due to competitive automatic transmissions with torque converters; clutch automated manual transmissions and dual clutch transmissions. Hybrid transmissions play a key role in comfort and performance enhancement while at the same time being fuel efficient with the aid of electric machines and battery packs. Here, the alternative to conventional add-on hybrid power head transmissions: the power split hybrid transmission is studied. As a practical example, the Two Mode of the Hybrid Development Center is used within the ML450 Hybrid. For achieving a smooth shifting, there are model based algorithms needed. As objective measure to evaluate the shifting the VDV (Vibration Dose Value) is used. (orig.)

  9. Cranial nerve injury after minor head trauma.

    Science.gov (United States)

    Coello, Alejandro Fernández; Canals, Andreu Gabarrós; Gonzalez, Juan Martino; Martín, Juan José Acebes

    2010-09-01

    There are no specific studies about cranial nerve (CN) injury following mild head trauma (Glasgow Coma Scale Score 14-15) in the literature. The aim of this analysis was to document the incidence of CN injury after mild head trauma and to correlate the initial CT findings with the final outcome 1 year after injury. The authors studied 49 consecutive patients affected by minor head trauma and CN lesions between January 2000 and January 2006. Detailed clinical and neurological examinations as well as CT studies using brain and bone windows were performed in all patients. Based on the CT findings the authors distinguished 3 types of traumatic injury: no lesion, skull base fracture, and other CT abnormalities. Patients were followed up for 1 year after head injury. The authors distinguished 3 grades of clinical recovery from CN palsy: no recovery, partial recovery, and complete recovery. Posttraumatic single nerve palsy was observed in 38 patients (77.6%), and multiple nerve injuries were observed in 11 (22.4%). Cranial nerves were affected in 62 cases. The most affected CN was the olfactory nerve (CN I), followed by the facial nerve (CN VII) and the oculomotor nerves (CNs III, IV, and VI). When more than 1 CN was involved, the most frequent association was between CNs VII and VIII. One year after head trauma, a CN deficit was present in 26 (81.2%) of the 32 cases with a skull base fracture, 12 (60%) of 20 cases with other CT abnormalities, and 3 (30%) of 10 cases without CT abnormalities. Trivial head trauma that causes a minor head injury (Glasgow Coma Scale Score 14-15) can result in CN palsies with a similar distribution to moderate or severe head injuries. The CNs associated with the highest incidence of palsy in this study were the olfactory, facial, and oculomotor nerves. The trigeminal and lower CNs were rarely damaged. Oculomotor nerve injury can have a good prognosis, with a greater chance of recovery if no lesion is demonstrated on the initial CT scan.

  10. Pediatric head injury.

    Science.gov (United States)

    Tulipan, N

    1998-01-01

    Pediatric head injury is a public health problem that exacts a high price from patients, their families and society alike. While much of the brain damage in head-injured patients occurs at the moment of impact, secondary injuries can be prevented by aggressive medical and surgical intervention. Modern imaging devices have simplified the task of diagnosing intracranial injuries. Recent advances in monitoring technology have made it easier to assess the effectiveness of medical therapy. These include intracranial pressure monitoring devices that are accurate and safe, and jugular bulb monitoring which provides a continuous, qualitative measure of cerebral blood flow. The cornerstones of treatment remain hyperventilation and osmotherapy. Despite maximal treatment, however, the mortality and morbidity associated with pediatric head injury remains high. Reduction of this mortality and morbidity will likely depend upon prevention rather than treatment.

  11. Metallothionein (MT)-III

    DEFF Research Database (Denmark)

    Carrasco, J; Giralt, M; Molinero, A

    1999-01-01

    Metallothionein-III is a low molecular weight, heavy-metal binding protein expressed mainly in the central nervous system. First identified as a growth inhibitory factor (GIF) of rat cortical neurons in vitro, it has subsequently been shown to be a member of the metallothionein (MT) gene family...... and renamed as MT-III. In this study we have raised polyclonal antibodies in rabbits against recombinant rat MT-III (rMT-III). The sera obtained reacted specifically against recombinant zinc-and cadmium-saturated rMT-III, and did not cross-react with native rat MT-I and MT-II purified from the liver of zinc...... injected rats. The specificity of the antibody was also demonstrated in immunocytochemical studies by the elimination of the immunostaining by preincubation of the antibody with brain (but not liver) extracts, and by the results obtained in MT-III null mice. The antibody was used to characterize...

  12. Head First Statistics

    CERN Document Server

    Griffiths, Dawn

    2009-01-01

    Wouldn't it be great if there were a statistics book that made histograms, probability distributions, and chi square analysis more enjoyable than going to the dentist? Head First Statistics brings this typically dry subject to life, teaching you everything you want and need to know about statistics through engaging, interactive, and thought-provoking material, full of puzzles, stories, quizzes, visual aids, and real-world examples. Whether you're a student, a professional, or just curious about statistical analysis, Head First's brain-friendly formula helps you get a firm grasp of statistics

  13. Head first Ajax

    CERN Document Server

    Riordan, Rebecca M

    2008-01-01

    Ajax is no longer an experimental approach to website development, but the key to building browser-based applications that form the cornerstone of Web 2.0. Head First Ajax gives you an up-to-date perspective that lets you see exactly what you can do -- and has been done -- with Ajax. With it, you get a highly practical, in-depth, and mature view of what is now a mature development approach. Using the unique and highly effective visual format that has turned Head First titles into runaway bestsellers, this book offers a big picture overview to introduce Ajax, and then explores the use of ind

  14. Rocket injector head

    Science.gov (United States)

    Green, C. W., Jr. (Inventor)

    1968-01-01

    A high number of liquid oxygen and gaseous hydrogen orifices per unit area are provided in an injector head designed to give intimate mixing and more thorough combustion. The injector head comprises a main body portion, a cooperating plate member as a flow chamber for one propellant, a cooperating manifold portion for the second propellant, and an annular end plate for enclosing an annular propellant groove formed around the outer edge of the body. All the openings for one propellant are located at the same angle with respect to a radial plane to permit a short combustion chamber.

  15. Research progress of III-V laser bonding to Si

    Science.gov (United States)

    Bo, Ren; Yan, Hou; Yanan, Liang

    2016-12-01

    The vigorous development of silicon photonics makes a silicon-based light source essential for optoelectronics' integration. Bonding of III-V/Si hybrid laser has developed rapidly in the last ten years. In the tireless efforts of researchers, we are privileged to see these bonding methods, such as direct bonding, medium adhesive bonding and low temperature eutectic bonding. They have been developed and applied to the research and fabrication of III-V/Si hybrid lasers. Some research groups have made remarkable progress. Tanabe Katsuaki of Tokyo University successfully implemented a silicon-based InAs/GaAs quantum dot laser with direct bonding method in 2012. They have bonded the InAs/GaAs quantum dot laser to the silicon substrate and the silicon ridge waveguide, respectively. The threshold current of the device is as low as 200 A/cm2. Stevan Stanković and Sui Shaoshuai successfully produced a variety of hybrid III-V/Si laser with the method of BCB bonding, respectively. BCB has high light transmittance and it can provide high bonding strength. Researchers of Tokyo University and Peking University have realized III-V/Si hybrid lasers with metal bonding method. We describe the progress in the fabrication of III-V/Si hybrid lasers with bonding methods by various research groups in recent years. The advantages and disadvantages of these methods are presented. We also introduce the progress of the growth of III-V epitaxial layer on silicon substrate, which is also a promising method to realize silicon-based light source. I hope that readers can have a general understanding of this field from this article and we can attract more researchers to focus on the study in this field.

  16. Hybrid microelectronic technology

    Science.gov (United States)

    Moran, P.

    Various areas of hybrid microelectronic technology are discussed. The topics addressed include: basic thick film processing, thick film pastes and substrates, add-on components and attachment methods, thin film processing, and design of thick film hybrid circuits. Also considered are: packaging hybrid circuits, automating the production of hybrid circuits, application of hybrid techniques, customer's view of hybrid technology, and quality control and assurance in hybrid circuit production.

  17. Heading in soccer: dangerous play?

    Science.gov (United States)

    Spiotta, Alejandro M; Bartsch, Adam J; Benzel, Edward C

    2012-01-01

    Soccer is the world's most popular sport and unique in that players use their unprotected heads to intentionally deflect, stop, or redirect the ball for both offensive and defensive strategies. Headed balls travel at high velocity pre- and postimpact. Players, coaches, parents, and physicians are justifiably concerned with soccer heading injury risk. Furthermore, risk of long-term neurocognitive and motor deficits caused by repetitively heading a soccer ball remains unknown. We review the theoretical concerns, the results of biomechanical laboratory experiments, and the available clinical data regarding the effects of chronic, subconcussive head injury during heading in soccer.

  18. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... are present in the paranasal sinuses. plan radiation therapy for cancer of the brain or other tissues. guide the ... RTAnswers.org Radiation Therapy for Brain Tumors Radiation Therapy for Head and Neck Cancer Others American Stroke Association National Stroke Association top ...

  19. Head space analysis

    NARCIS (Netherlands)

    Stekelenburg, G.J. van; Koorevaar, G.

    Additional analytical information is given about the method of head space analysis. From the data presented it can be concluded that this technique may be advantageous for enzyme kinetic studies in turbid solutions, provided a volatile organic substance is involved in the chemical reaction. Also

  20. Sculpting Ceramic Heads.

    Science.gov (United States)

    Sapiro, Maurice

    1983-01-01

    Clay sculpture is difficult to produce because of the requirements of kiln firing. The problems can be overcome by modeling the original manikin head and making a plaster mold, pressing molding slabs of clay into the plaster mold to form the hollow clay armature, and sculpting on the armature. (IS)

  1. Lubricating the swordfish head

    NARCIS (Netherlands)

    Videler, John J.; Haydar, Deniz; Snoek, Roelant; Hoving, Henk-Jan T.; Szabo, Ben G.

    2016-01-01

    The swordfish is reputedly the fastest swimmer on Earth. The concave head and iconic sword are unique characteristics, but how they contribute to its speed is still unknown. Recent computed tomography scans revealed a poorly mineralised area near the base of the rostrum. Here we report, using magnet

  2. Prognosis in head injury.

    Science.gov (United States)

    Jane, J A; Rimel, R W

    1982-01-01

    The prognosis of head injury when viewed from the perspective of the Glasgow Coma Scale confirms the utility of this measure. In particular, decrease in mortality is associated with an increase in GCS. In addition, the motor score portion of the GCS was of predictive value when taken alone. The outcome of patients in coma (GCS less than 8) was closely related to three preventable or treatable factors, namely, hypoxia, shock, and increased intracranial pressure. These three factors, when considered in combination, powerfully predicted mortality. Of considerable interest was the finding that moderate head injury (GCS 9-12) was associated with a small but perhaps preventable mortality. The morbidity was intermediate between that of severe and minor and was surprisingly high. Minor head injury, while not associated with significant mortality, also resulted in considerable morbidity. Neuropsychological evaluation of the patients and an experimental study suggests that an organic component may be involved even in this group. To deal with head injury, distinctions must be made between grades of severity. The Glasgow Coma Scale is suited for this task. Nonetheless, the recognition of this basic continuity should elicit the further recognition that different health providers may be involved in the case of, say, severe, as opposed to mild, injury, and that different outcome measures are suitable for one group but not another.

  3. Head injuries, heading, and the use of headgear in soccer.

    Science.gov (United States)

    Niedfeldt, Mark W

    2011-01-01

    Soccer has more than 265 million players around the world and is the only contact sport with purposeful use of the head for controlling and advancing the ball. Head contact in soccer has the potential to cause acute traumatic brain injury including concussion or, potentially, a pattern of chronic brain injury. Although early retrospective research on the effects of soccer heading seemed to suggest that purposeful heading may contribute to long-term cognitive impairment, prospective controlled studies do not support this and, in fact, suggest that purposeful heading may not be a risk factor for cognitive impairment. Headgear has not been shown to be effective in reducing ball impact but may be helpful in reducing the force of non-ball-related impacts to the head. There are concerns that universal use of headgear may cause more aggressive heading and head challenges, leading to increased risk of injury.

  4. Hypersensitive Response-Like Reaction Is Associated with Hybrid Necrosis in Interspecific Crosses between Tetraploid Wheat and Aegilops tauschii Coss

    OpenAIRE

    Nobuyuki Mizuno; Naoki Hosogi; Pyoyun Park; Shigeo Takumi

    2010-01-01

    BACKGROUND: Hybrid speciation is classified into homoploid and polyploid based on ploidy level. Common wheat is an allohexaploid species that originated from a naturally occurring interploidy cross between tetraploid wheat and diploid wild wheat Aegilops tauschii Coss. Aegilops tauschii provides wide naturally occurring genetic variation. Sometimes its triploid hybrids with tetraploid wheat show the following four types of hybrid growth abnormalities: types II and III hybrid necrosis, hybrid ...

  5. ASCO highlights podcast: head and neck cancers.

    Science.gov (United States)

    Merlano, Marco

    2016-01-01

    A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial comparing gemcitabine plus cisplatin against 5-FU (5-fluorouracil) plus cisplatin in the treatment of nasopharyngeal carcinoma is highlighted. The GORTEC2007-02 trial comparing induction docetaxel/platinum/5-FU followed by cetuximab-radiotherapy against concurrent chemo-radiotherapy for N2b/c-N3 non operated stage III-IV squamous cell cancer of the head and neck is also discussed. An overview of the research reported using immunotherapy in head and neck cancer is also given, considering maturing data and particularly in relapsing patients, where response rates, though low, are better than with current therapies, and the responses are long lasting. Future developments are also considered, again with a focus on immunotherapy, but also considering combination with radiotherapy and chemoradiation.

  6. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... content. Related Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain ...

  7. Head Lice: Prevention and Control

    Science.gov (United States)

    ... Diseases Laboratory Diagnostic Assistance [DPDx] Parasites Home Prevention & Control Language: English Español (Spanish) Recommend on Facebook Tweet ... that can be taken to help prevent and control the spread of head lice: Avoid head-to- ...

  8. Head and Neck Cancer Treatment

    Science.gov (United States)

    ... Professions Site Index A-Z Head and Neck Cancer Treatment Head and neck cancer overview What are my ... and neck cancer. For updated information on new cancer treatments that are available, you should discuss these issues ...

  9. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... to remain perfectly still and follow breath-holding instructions while the images are being recorded. If you ... Images related to Magnetic Resonance Imaging (MRI) - Head Videos related to Magnetic Resonance Imaging (MRI) - Head Sponsored ...

  10. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... the limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) ... ray, CT and ultrasound. top of page How is the procedure performed? MRI examinations may be performed ...

  11. Head and Neck Cancer Treatment

    Science.gov (United States)

    ... oncologist will listen to the history of your problem and perform a physical examination. Consultations with other members of the head and neck team, such as the head and neck surgeon, pathologist, ...

  12. Sports-related Head Injury

    Science.gov (United States)

    ... difficulty expressing words or thoughts; dysarthric speech Head Injury Prevention Tips Buy and use helmets or protective head gear approved by the ASTM for specific sports 100 percent of the time. The ASTM has ...

  13. Preventing head injuries in children

    Science.gov (United States)

    Concussion - preventing in children; Traumatic brain injury - preventing in children; TBI - children; Safety - preventing head injury ... Helmets help to prevent head injuries. Your child should wear a ... sports or activities: Playing contact sports, such as lacrosse, ...

  14. Hybrid Gear

    Science.gov (United States)

    Handschuh, Robert F. (Inventor); Roberts, Gary D. (Inventor)

    2016-01-01

    A hybrid gear consisting of metallic outer rim with gear teeth and metallic hub in combination with a composite lay up between the shaft interface (hub) and gear tooth rim is described. The composite lay-up lightens the gear member while having similar torque carrying capability and it attenuates the impact loading driven noise/vibration that is typical in gear systems. The gear has the same operational capability with respect to shaft speed, torque, and temperature as an all-metallic gear as used in aerospace gear design.

  15. Hybrid Qualifications

    DEFF Research Database (Denmark)

    has turned out as a major focus of European education and training policies and certainly is a crucial principle underlying the European Qualifications Framework (EQF). In this context, «hybrid qualifications» (HQ) may be seen as an interesting approach to tackle these challenges as they serve «two...... masters», i.e. by producing skills for the labour market and enabling individuals to progress more or less directly to higher education. The specific focus of this book is placed on conditions, structures and processes which help to combine VET with qualifications leading into higher education...

  16. Plant characters of broccoli determinants of head production

    OpenAIRE

    Fernanda Daniela Brandelero; Betania Brum; Lindolfo Storck; Jessica Cardoso; Talita Slota Kutz; Thiago de Oliveira Vargas

    2016-01-01

    ABSTRACT: The increasing consumption of single-head broccoli is due to several factors, among them there are food production in minimally processing form and the existence of hybrids that adapt to various climates, in addition to the simple harvesting of this typical architecture.This study aimed to identify the most relevant plant characters of broccoli, represented by growth characters, which are determinant in the production and canopy area. The study was conducted in an experimental area ...

  17. "Head versus heart"

    Directory of Open Access Journals (Sweden)

    Paul Rozin

    2007-08-01

    Full Text Available Most American respondents give ``irrational,'' magical responses in a variety of situations that exemplify the sympathetic magical laws of similarity and contagion. In most of these cases, respondents are aware that their responses (usually rejections, as of fudge crafted to look like dog feces, or a food touched by a sterilized, dead cockroach are not ``scientifically'' justified, but they are willing to avow them. We interpret this, in some sense, as ``heart over head.'' We report in this study that American adults and undergraduates are substantially less likely to acknowledge magical effects when the judgments involve money (amount willing to pay to avoid an ``unpleasant'' magical contact than they are when using preference or rating measures. We conclude that in ``head-heart'' conflicts of this type, money tips the balance towards the former, or, in other words, that money makes the mind less magical.

  18. 小白菜与大白菜亚种间杂交减数分裂染色体行为观察%Chromosome Behaviors in Meiotic of Pollen Mother Cells in Inter-subspecific Hybridization between Chinese Cabbage and Non-heading Chinese Cabbage

    Institute of Scientific and Technical Information of China (English)

    陈龙正; 徐海; 宋波; 樊小雪

    2015-01-01

    Meiotic behaviors of pollen mother cells ( PMCs) in inter-subspecific hybrid F1 and BC1-3 be⁃tween Chinese cabbage and non-heading Chinese cabbage were studied. It was observed that 90.7%of F1 pollen were stainable, indicating good fertility. The fertility of BC1-3 was gradually increased. 89.1%chro⁃mosome behavior in F1 meiotic PMCs was regular which could explain the good fertility. Abnormal chro⁃mosome behaviors such as double nucleoli, disordered paring in Prophase I, chromosome bridge in meta⁃phase I, segments loss in anaphase I were discovered which could explain the lower fertility of F1 hybrid than normal diploid. 14.3% abnormal chromosome behaviors were found in BC1 generation however very limited in BC2-3 which indicated that it was a repaid process for chromosome behavior of backcross genera⁃tion becoming normal;this result was consistent to phenotype and fertility investigation.%研究了小白菜与大白菜亚种间杂交及回交世代花粉母细胞减数分裂行为,发现杂种F1花粉可染率90.7%,表现出较好的育性;回交BC1-3花粉可染率升高,表明育性逐步提高.F1花粉母细胞减数分裂正常染色体行为细胞数占总观察数的89.1%,这解释了F1具有较好育性的原因.杂种F1减数分裂各个时期会出现不正常现象,如双核仁、配对紊乱、染色体桥、染色体片段丢失等,这在一定程度上可以说明杂种F1育性低于正常二倍体的原因.14.3%的BC1花粉母细胞会出现不正常现象,而BC2-3已经相对正常,极少观察到减数分裂不正常现象,表明在回交过程中染色体稳定是一个快速的过程,这与表型及育性调查结果相吻合.

  19. "Head versus heart"

    OpenAIRE

    2007-01-01

    Most American respondents give ``irrational,'' magical responses in a variety of situations that exemplify the sympathetic magical laws of similarity and contagion. In most of these cases, respondents are aware that their responses (usually rejections, as of fudge crafted to look like dog feces, or a food touched by a sterilized, dead cockroach) are not ``scientifically'' justified, but they are willing to avow them. We interpret this, in some sense, as ``heart over head.'' We report in this ...

  20. Intuitionistic hybrid logic

    DEFF Research Database (Denmark)

    Braüner, Torben

    2011-01-01

    Intuitionistic hybrid logic is hybrid modal logic over an intuitionistic logic basis instead of a classical logical basis. In this short paper we introduce intuitionistic hybrid logic and we give a survey of work in the area.......Intuitionistic hybrid logic is hybrid modal logic over an intuitionistic logic basis instead of a classical logical basis. In this short paper we introduce intuitionistic hybrid logic and we give a survey of work in the area....

  1. Continuity Controlled Hybrid Automata

    OpenAIRE

    Bergstra, J. A.; Middelburg, C.A.

    2004-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of hybrid automata as timed transition systems. We also relate the synchronized product operator on hybrid automata to the parallel composition operator of the process algebra. It turns out that the f...

  2. Syntactic-Head-Driven Generation

    CERN Document Server

    Koenig, E

    1994-01-01

    The previously proposed semantic-head-driven generation methods run into problems if none of the daughter constituents in the syntacto-semantic rule schemata of a grammar fits the definition of a semantic head given in Shieber et al. 1990. This is the case for the semantic analysis rules of certain constraint-based semantic representations, e.g. Underspecified Discourse Representation Structures (UDRSs) (Frank/Reyle 1992). Since head-driven generation in general has its merits, we simply return to a syntactic definition of `head' and demonstrate the feasibility of syntactic-head-driven generation. In addition to its generality, a syntactic-head-driven algorithm provides a basis for a logically well-defined treatment of the movement of (syntactic) heads, for which only ad-hoc solutions existed, so far.

  3. The type III manufactory

    CERN Document Server

    Palcoux, Sébastien

    2011-01-01

    Using unusual objects in the theory of von Neumann algebra, as the chinese game Go or the Conway game of life (generalized on finitely presented groups), we are able to build, by hands, many type III factors.

  4. Hybridized tetraquarks

    Directory of Open Access Journals (Sweden)

    A. Esposito

    2016-07-01

    Full Text Available We propose a new interpretation of the neutral and charged X,Z exotic hadron resonances. Hybridized-tetraquarks are neither purely compact tetraquark states nor bound or loosely bound molecules but rather a manifestation of the interplay between the two. While meson molecules need a negative or zero binding energy, its counterpart for h-tetraquarks is required to be positive. The formation mechanism of this new class of hadrons is inspired by that of Feshbach metastable states in atomic physics. The recent claim of an exotic resonance in the Bs0π± channel by the D0 Collaboration and the negative result presented subsequently by the LHCb Collaboration are understood in this scheme, together with a considerable portion of available data on X,Z particles. Considerations on a state with the same quantum numbers as the X(5568 are also made.

  5. Hybridized Tetraquarks

    CERN Document Server

    Esposito, A.; Polosa, A.D.

    2016-01-01

    We propose a new interpretation of the neutral and charged X, Z exotic hadron resonances. Hybridized-tetraquarks are neither purely compact tetraquark states nor bound or loosely bound molecules. The latter would require a negative or zero binding energy whose counterpart in h-tetraquarks is a positive quantity. The formation mechanism of this new class of hadrons is inspired by that of Feshbach metastable states in atomic physics. The recent claim of an exotic resonance in the Bs pi+- channel by the D0 collaboration and the negative result presented subsequently by the LHCb collaboration are understood in this scheme, together with a considerable portion of available data on X, Z particles. Considerations on a state with the same quantum numbers as the X(5568) are also made.

  6. A comparison of clinically utilized human papillomavirus detection methods in head and neck cancer

    OpenAIRE

    Schlecht, Nicolas F.; Brandwein-Gensler, Margaret; Gerard J Nuovo; Li, Maomi; Dunne, Anne; Kawachi, Nicole; Smith, Richard V.; Burk, Robert D.; Prystowsky, Michael B.

    2011-01-01

    Detection of human papillomavirus in head and neck cancer has therapeutic implications. In-situ hybridization and immuno-histochemistry for p16 are used by surgical pathologists. We compared the sensitivity and specificity of three popular commercial tests for human papillomavirus detection in head and neck squamous cell carcinomas to a “gold standard” human papillomavirus PCR assay. One hundred-and-ten prospectively collected, formalin fixed tumor specimens were compiled onto tissue microarr...

  7. Hybrid Integrated Platforms for Silicon Photonics

    Directory of Open Access Journals (Sweden)

    John E. Bowers

    2010-03-01

    Full Text Available A review of recent progress in hybrid integrated platforms for silicon photonics is presented. Integration of III-V semiconductors onto silicon-on-insulator substrates based on two different bonding techniques is compared, one comprising only inorganic materials, the other technique using an organic bonding agent. Issues such as bonding process and mechanism, bonding strength, uniformity, wafer surface requirement, and stress distribution are studied in detail. The application in silicon photonics to realize high-performance active and passive photonic devices on low-cost silicon wafers is discussed. Hybrid integration is believed to be a promising technology in a variety of applications of silicon photonics.

  8. Biperiodic nanostructured waveguides for wavelength-selectivity of hybrid photonic devices.

    Science.gov (United States)

    Talneau, A; Pommarède, X; Itawi, A; Pantzas, K; Lupu, A; Benisty, H

    2015-11-15

    A biperiodic nanostructuration consisting of a super-periodicity added to a nanohole lattice of subwavelength pitch is demonstrated to provide both modal confinement and wavelength selectivity within a hybrid III-V on a silicon waveguide. The wavelength-selective behavior stems from finely tuned larger holes. Such biperiodic hybrid waveguides have been fabricated by oxide-free bonding III-V material on silicon and display well-defined stop bands. Such nanostructured waveguides offer the versatility for designing advanced optical functions within hybrid devices. Moreover, keeping the silicon waveguide surface planar, such nanostructured waveguides are compatible with electrical operation across the oxide-free hybrid interface.

  9. High-Dose Recombinant Interferon Alfa-2B, Ipilimumab, or Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery

    Science.gov (United States)

    2016-10-10

    Metastatic Non-Cutaneous Melanoma; Non-Cutaneous Melanoma; Recurrent Melanoma of the Skin; Recurrent Non-Cutaneous Melanoma; Stage III Mucosal Melanoma of the Head and Neck; Stage IIIA Skin Melanoma; Stage IIIB Skin Melanoma; Stage IIIC Skin Melanoma; Stage IV Skin Melanoma; Stage IVA Mucosal Melanoma of the Head and Neck; Stage IVB Mucosal Melanoma of the Head and Neck; Stage IVC Mucosal Melanoma of the Head and Neck

  10. [Genetic basis of head and neck cancers and gene therapy].

    Science.gov (United States)

    Özel, Halil Erdem; Özkırış, Mahmut; Gencer, Zeliha Kapusuz; Saydam, Levent

    2013-01-01

    Surgery and combinations of traditional treatments are not successful enough particularly for advanced stage head and neck cancer. The major disadvantages of chemotherapy and radiation therapy are the lack of specificity for the target tissue and toxicity to the patient. As a result, gene therapy may offer a more specific approach. The aim of gene therapy is to present therapeutic genes into cancer cells which selectively eliminate malignant cells with no systemic toxicity to the patient. This article reviews the genetic basis of head and neck cancers and important concepts in cancer gene therapy: (i) inhibition of oncogenes; (ii) tumor suppressor gene replacement; (iii) regulation of immune response against malignant cells; (iv) genetic prodrug activation; and (v) antiangiogenic gene therapy. Currently, gene therapy is not sufficient to replace the traditional treatments of head and neck cancers, however there is no doubt that it will have an important role in the near future.

  11. Head first C#

    CERN Document Server

    Stellman, Andrew

    2008-01-01

    Head First C# is a complete learning experience for object-oriented programming, C#, and the Visual Studio IDE. Built for your brain, this book covers C# 3.0 and Visual Studio 2008, and teaches everything from language fundamentals to advanced topics including garbage collection, extension methods, and double-buffered animation. You'll also master C#'s hottest and newest syntax, LINQ, for querying SQL databases, .NET collections, and XML documents. By the time you're through, you'll be a proficient C# programmer, designing and coding large-scale applications. Every few chapters you will come

  12. Head first C#

    CERN Document Server

    Stellman, Andrew

    2010-01-01

    You want to learn C# programming, but you're not sure you want to suffer through another tedious technical book. You're in luck: Head First C# introduces this language in a fun, visual way. You'll quickly learn everything from creating your first program to learning sophisticated coding skills with C# 4.0, Visual Studio 2010 and .NET 4, while avoiding common errors that frustrate many students. The second edition offers several hands-on labs along the way to help you build and test programs using skills you've learned up to that point. In the final lab, you'll put everything together. From o

  13. Head First Python

    CERN Document Server

    Barry, Paul

    2010-01-01

    Ever wished you could learn Python from a book? Head First Python is a complete learning experience for Python that helps you learn the language through a unique method that goes beyond syntax and how-to manuals, helping you understand how to be a great Python programmer. You'll quickly learn the language's fundamentals, then move onto persistence, exception handling, web development, SQLite, data wrangling, and Google App Engine. You'll also learn how to write mobile apps for Android, all thanks to the power that Python gives you. We think your time is too valuable to waste struggling with

  14. Head First Web Design

    CERN Document Server

    Watrall, Ethan

    2008-01-01

    Want to know how to make your pages look beautiful, communicate your message effectively, guide visitors through your website with ease, and get everything approved by the accessibility and usability police at the same time? Head First Web Design is your ticket to mastering all of these complex topics, and understanding what's really going on in the world of web design. Whether you're building a personal blog or a corporate website, there's a lot more to web design than div's and CSS selectors, but what do you really need to know? With this book, you'll learn the secrets of designing effecti

  15. Head First Mobile Web

    CERN Document Server

    Gardner, Lyza; Grigsby, Jason

    2011-01-01

    Despite the huge number of mobile devices and apps in use today, your business still needs a website. You just need it to be mobile. Head First Mobile Web walks you through the process of making a conventional website work on a variety smartphones and tablets. Put your JavaScript, CSS media query, and HTML5 skills to work-then optimize your site to perform its best in the demanding mobile market. Along the way, you'll discover how to adapt your business strategy to target specific devices. Navigate the increasingly complex mobile landscapeTake both technical and strategic approaches to mobile

  16. Analysis on Dry Matter Production Characteristics of Super Hybrid Rice

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Six middle-season indica hybrid rice combinations,including five super hybrid rice combinations with the high yield about 10.5 t/ha and a check hybrid rice combination Shanyou 63 with a yield potential about 9.5 t/ha,were used as materials to study the dry matter production characteristics.The super hybrid rice showed a high ability in dry matter production and accumulation and its yield enhanced with the increase of dry matter accumulation.The advantage period of dry matter production in the super hybrid rice was mainly at the middle and late growth stages compared with the check.The grain yield had no significant correlation with the dry matter accumulation before the elongation stage while had a significantly positive correlation with the dry matter accumulation from the elongation to maturity stages in super hybrid rice.There were more dry matter in vegetative organs at the heading stage in the super hybrid rice but its contribution to yield (apparent conversion percentage) was averagely 4.3 percent points lower than that in the check.For crop growth rate (CGR),the comparative advantage of super hybrid rice was at the middle and late stages,especially after flowering.Moreover,as the rising of leaf area index (LAI) and leaf area duration (LAD),CGR enhanced.The total LAD and the mean of LAD per day of super hybrid rice was about 14.79% and 10.31% higher than those of the check,respectively.The results indicate that the high yield of super hybrid rice mostly comes from the products of photosynthesis after heading,which is shown by the increased CGR at middle and later stages.It is suggested that LAD character might be used to better explain the advantage in the dry matter production of super hybrid rice than LAI.

  17. Association between temporomandibular disorders and abnormal head postures

    Directory of Open Access Journals (Sweden)

    Evandro Francisco FAULIN

    2015-01-01

    Full Text Available This study examines the possible correlation between the prevalence of temporomandibular disorders (TMD and different head postures in the frontal and sagittal planes using photographs of undergraduate students in the School of Dentistry at the Universidade de Brasília - UnB, Brazil. In this nonrandomized, cross-sectional study, the diagnoses of TMD were made with the Research Diagnostic Criteria (RDC/TMD axis I. The craniovertebral angle was used to evaluate forward head posture in the sagittal plane, and the interpupillary line was used to measure head tilt in the frontal plane. The measurements to evaluate head posture were made using the Software for the Assessment of Posture (SAPO. Students were divided into two study groups, based on the presence or absence of TMD. The study group comprised 46 students and the control group comprised 80 students. Data about head posture and TMD were analyzed with the Statistical Package for the Social Sciences, version 13. Most cases of TMD were classified as degenerative processes (group III, followed by disk displacement (group II and muscle disorders (group I. There was no sex predominance for the type of disorder. No association was found between prevalence rates for head postures in the frontal plane and the occurrence of TMD. The same result was found for the association of TMD diagnosis with craniovertebral angle among men and women, and the group that contained both men and women. Abnormal head postures were common among individuals both with and without TMD. No association was found between head posture evaluated in the frontal and sagittal planes and TMD diagnosis with the use of RDC/TMD.

  18. Effects of Olympic-style taekwondo kicks on an instrumented head-form and resultant injury measures.

    Science.gov (United States)

    Fife, Gabriel P; O'Sullivan, David M; Pieter, Willy; Cook, David P; Kaminski, Thomas W

    2013-12-01

    The objective of this study was to assess the effect of taekwondo kicks and peak foot velocity (FVEL) on resultant head linear acceleration (RLA), head injury criterion (HIC15) and head velocity (HVEL). Each subject (n=12) randomly performed five repetitions of the turning kick (TK), clench axe kick (CA), front leg axe kick, jump back kick (JB) and jump spinning hook kick (JH) at the average standing head height for competitors in their weight division. A Hybrid II Crash Test Dummy head was fitted with a protective taekwondo helmet and instrumented with a triaxial accelerometer and fixed to a height-adjustable frame. Resultant head linear acceleration, HVEL, FVEL data were captured and processed using Qualysis Track Manager. The TK (130.11 ± 51.67 g) produced a higher RLA than the CA (54.95 ± 20.08 g, ptaekwondo. Future studies should aim to understand rotational accelerations of the head.

  19. Continuity Controlled Hybrid Automata

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2004-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of

  20. Continuity controlled Hybrid Automata

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2008-01-01

    We investigate the connections between the process algebra for hybrid systems of Bergstra and Middelburg and the formalism of hybrid automata of Henzinger et al. We give interpretations of hybrid automata in the process algebra for hybrid systems and compare them with the standard interpretation of

  1. p16 expression in cutaneous squamous carcinomas with neck metastases: a potential pitfall in identifying unknown primaries of the head and neck.

    Science.gov (United States)

    Beadle, Beth M; William, William N; McLemore, Michael S; Sturgis, Erich M; Williams, Michelle D

    2013-11-01

    Human papillomavirus (HPV) positivity (+) has been used to identify oropharyngeal squamous carcinomas (SCCs) presenting as unknown primaries in the neck. p16 overexpression correlates with HPV+ in the oropharynx; however, the use of p16 alone as a surrogate marker of oropharyngeal HPV+ tumors has not been validated. We immunohistochemically analyzed p16 expression in surgically resected aggressive cutaneous head and neck SCC primaries and their nodal metastases from 24 patients to determine the potential overlap of p16 expression outside of the oropharynx. Five of 24 primary tumors (20.8%) and 3 lymph node metastases (12.5%) in levels II, III, and V, and the periparotid region diffusely expressed p16. HPV (high-risk types by in situ hybridization) was negative. p16 expression is relatively common in lymph node-positive cutaneous head and neck SCCs; thus, p16 expression as an independent biomarker and mechanism to determine the oropharyngeal source of an unknown primary is not advised. Copyright © 2012 Wiley Periodicals, Inc.

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles ... Videos related to Magnetic Resonance Imaging (MRI) - Head Sponsored ...

  3. The hybrid state: crime and citizenship in urban Jamaica

    NARCIS (Netherlands)

    Jaffe, R.

    2013-01-01

    In inner-city neighborhoods in Kingston, Jamaica, criminal "dons" have taken on a range of governmental functions. While such criminal actors have sometimes been imagined as heading "parallel states," I argue that they are part of a hybrid state, an emergent political formation in which multiple

  4. The hybrid state: crime and citizenship in urban Jamaica

    NARCIS (Netherlands)

    Jaffe, R.

    2013-01-01

    In inner-city neighborhoods in Kingston, Jamaica, criminal "dons" have taken on a range of governmental functions. While such criminal actors have sometimes been imagined as heading "parallel states," I argue that they are part of a hybrid state, an emergent political formation in which multiple gov

  5. Wizlaw III og minnesangen

    DEFF Research Database (Denmark)

    Pontoppidan, Maria

    2012-01-01

    Artikel om den sidste slaviske Rügenfyrste, Wizlaw III (1265/68-1325), der traditionelt har været identificeret med minnesangeren Wizlaw den Unge. Om de bevarede sange og om minnesangens rolle ved det rügenske fyrstehof.......Artikel om den sidste slaviske Rügenfyrste, Wizlaw III (1265/68-1325), der traditionelt har været identificeret med minnesangeren Wizlaw den Unge. Om de bevarede sange og om minnesangens rolle ved det rügenske fyrstehof....

  6. III-V microelectronics

    CERN Document Server

    Nougier, JP

    1991-01-01

    As is well known, Silicon widely dominates the market of semiconductor devices and circuits, and in particular is well suited for Ultra Large Scale Integration processes. However, a number of III-V compound semiconductor devices and circuits have recently been built, and the contributions in this volume are devoted to those types of materials, which offer a number of interesting properties. Taking into account the great variety of problems encountered and of their mutual correlations when fabricating a circuit or even a device, most of the aspects of III-V microelectronics, from fundamental p

  7. HEADS UP: Sensorimotor control of the head-neck system

    NARCIS (Netherlands)

    Forbes, P.A.

    2014-01-01

    Head-neck stabilization is inherently challenging even when stationary, requiring constant vigilance to counter the downward pull of gravity. It involves a highly complex biomechanical system comprised of a large mass (the head) balanced on top of seven vertebrae (the neck), that are in turn connect

  8. Hybrid and monolithic integration of planar lightwave circuits (PLCs)

    Science.gov (United States)

    Chen, Ray T.

    2008-02-01

    In this paper, we review the status of monolithic and hybrid integration of planar lightwave circuits (PLCs). Building blocks needed for system integration based on polymeric materials, III-V semiconductor materials, LiNbO 3 and SOI on Silicon are summarized with pros and cons. Due to the maturity of silicon CMOS technology, silicon becomes the platform of choice for optical application specific integrated circuits (OASICs). However, the indirect bandgap of silicon makes the formation of electrically pumped silicon laser a remote plausibility which requires hybrid integration of laser sources made out of III-V compound semicouductor.

  9. Chryse 'Alien Head'

    Science.gov (United States)

    2005-01-01

    26 January 2004 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows an impact crater in Chryse Planitia, not too far from the Viking 1 lander site, that to seems to resemble a bug-eyed head. The two odd depressions at the north end of the crater (the 'eyes') may have formed by wind or water erosion. This region has been modified by both processes, with water action occurring in the distant past via floods that poured across western Chryse Planitia from Maja Valles, and wind action common occurrence in more recent history. This crater is located near 22.5oN, 47.9oW. The 150 meter scale bar is about 164 yards long. Sunlight illuminates the scene from the left/lower left.

  10. NASA head sworn in

    Science.gov (United States)

    James C. Fletcher was sworn in on May 12, 1986, as administrator of the National Aeronautics and Space Administration (NASA). At a news conference after he was sworn in, Fletcher said that NASA would deal with both its technical problems and its procedural problems before the shuttle will fly again. According to press accounts, he stressed that funds should be made available to replace the Challenger orbiter, which was lost in an explosion on January 28.Fletcher, who had also headed the agency from 1971 to 1977, succeeds James M. Beggs, who was indicted in December 1985 for conspiring to defraud the federal government while serving as a senior executive at the General Dynamics Corporation.

  11. Radial head fracture associated with posterior interosseous nerve injury

    Directory of Open Access Journals (Sweden)

    Bernardo Barcellos Terra

    Full Text Available ABSTRACT Fractures of the radial head and radial neck correspond to 1.7-5.4% of all fractures and approximately 30% may present associated injuries. In the literature, there are few reports of radial head fracture with posterior interosseous nerve injury. This study aimed to report a case of radial head fracture associated with posterior interosseous nerve injury. CASE REPORT: A male patient, aged 42 years, sought medical care after falling from a skateboard. The patient related pain and limitation of movement in the right elbow and difficulty to extend the fingers of the right hand. During physical examination, thumb and fingers extension deficit was observed. The wrist extension showed a slight radial deviation. After imaging, it became evident that the patient had a fracture of the radial head that was classified as grade III in the Mason classification. The patient underwent fracture fixation; at the first postoperative day, thumb and fingers extension was observed. Although rare, posterior interosseous nerve branch injury may be associated with radial head fractures. In the present case, the authors believe that neuropraxia occurred as a result of the fracture hematoma and edema.

  12. The head-mounted microscope.

    Science.gov (United States)

    Chen, Ting; Dailey, Seth H; Naze, Sawyer A; Jiang, Jack J

    2012-04-01

    Microsurgical equipment has greatly advanced since the inception of the microscope into the operating room. These advancements have allowed for superior surgical precision and better post-operative results. This study focuses on the use of the Leica HM500 head-mounted microscope for the operating phonosurgeon. The head-mounted microscope has an optical zoom from 2× to 9× and provides a working distance from 300 mm to 700 mm. The headpiece, with its articulated eyepieces, adjusts easily to head shape and circumference, and offers a focus function, which is either automatic or manually controlled. We performed five microlaryngoscopic operations utilizing the head-mounted microscope with successful results. By creating a more ergonomically favorable operating posture, a surgeon may be able to obtain greater precision and success in phonomicrosurgery. Phonomicrosurgery requires the precise manipulation of long-handled cantilevered instruments through the narrow bore of a laryngoscope. The head-mounted microscope shortens the working distance compared with a stand microscope, thereby increasing arm stability, which may improve surgical precision. Also, the head-mounted design permits flexibility in head position, enabling operator comfort, and delaying musculoskeletal fatigue. A head-mounted microscope decreases the working distance and provides better ergonomics in laryngoscopic microsurgery. These advances provide the potential to promote precision in phonomicrosurgery. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

  13. Eye-based head gestures

    DEFF Research Database (Denmark)

    Mardanbegi, Diako; Witzner Hansen, Dan; Pederson, Thomas

    2012-01-01

    A novel method for video-based head gesture recognition using eye information by an eye tracker has been proposed. The method uses a combination of gaze and eye movement to infer head gestures. Compared to other gesture-based methods a major advantage of the method is that the user keeps the gaze...

  14. Kansas: Early Head Start Initiative

    Science.gov (United States)

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Kansas Early Head Start (KEHS) provides comprehensive services following federal Head Start Program Performance Standards for pregnant women and eligible families with children from birth to age 4. KEHS was implemented in 1998 using Child Care and Development Block Grant (CCDBG) quality set-aside dollars augmented by a transfer of federal…

  15. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... bear denotes child-specific content. Related Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain Tumors Images related to Magnetic ...

  16. Clinical trials in head injury

    NARCIS (Netherlands)

    Narayan, RK; Michel, ME

    2002-01-01

    Traumatic brain injury (TBI) remains a major public health problem globally. In the United States the incidence of closed head injuries admitted to hospitals is conservatively estimated to be 200 per 100,000 population, and the incidence of penetrating head injury is estimated to be 12 per 100,000,

  17. Integration of III-V materials and Si-CMOS through double layer transfer process

    Science.gov (United States)

    Lee, Kwang Hong; Bao, Shuyu; Fitzgerald, Eugene; Tan, Chuan Seng

    2015-03-01

    A method to integrate III-V compound semiconductor and SOI-CMOS on a common Si substrate is demonstrated. The SOI-CMOS layer is temporarily bonded on a Si handle wafer. Another III-V/Si substrate is then bonded to the SOI-CMOS containing handle wafer. Finally, the handle wafer is released to realize the SOI-CMOS on III-V/Si hybrid structure on a common substrate. Through this method, high temperature III-V materials growth can be completed without the presence of the temperature sensitive CMOS layer, hence damage to the CMOS layer is avoided.

  18. Gross and Histomorphological Studies of Femoral Head Resurfacing in Dog

    Directory of Open Access Journals (Sweden)

    D. Sharifi

    2006-01-01

    Full Text Available The foetal skull bone as a biological graft was investigated. This study was conducted on Fifteen adult mixed - breed normal dogs 12 to 24 months with weighing 21.4=3.6 Kg .Dogs were randomly divided into 3 groups of 5 animals each. The foetal skull bone of 45 days old was collected from one pregnant bitch via cesarean method. The right femoral head cartilage was removed completely in all dogs of 3 groups.. Group I acted as control one, whereas in II group, resurfacing was done by using foetal skull bone which was fixed by using 0.8 mm cerclage wire in criss-cross fashion, but in III group, it was done similar to II group and the hip joint additionally was fixed by using 2 mm steinmenn pin.The clinical observations was made accordingly for 60 days in all groups. The gross changes of femoral head in group I & II were quite smooth and slippy, but in III group were uneven and rough due to secondary changes and ankylosis, but on micropscopic interpertation there was a remarkable compatibility of the graft with femoral head.The reconstruction of articular cartilage was faster in group II and even group III animals than group I animals. There was single row of chondrocyte in scatter area of samples in group . The complete and uniform hyaline cartilage in group II and fibro - cartilage and mixture of connective tissues in group III animals were observed. The results indicated that the foetal skull bone due to its pleuripotent calvarium easily can orient itself into the chondrocytes and cartilagenous tissues in articular surface of the hip joint, if there is suitable enviroment before complete ossification,so that normal joint motion could expect.

  19. Comparing discriminant analysis and neural network for the determination of sex using femur head measurements.

    Science.gov (United States)

    Alunni, Véronique; Jardin, Philippe du; Nogueira, Luisa; Buchet, Luc; Quatrehomme, Gérald

    2015-08-01

    The measurement of the femoral head is usually considered an interesting variable for the sex determination of skeletal remains. To date, there are few published reference measurements of the femoral head in a modern European population for the purpose of sex determination. In this study, 116 femurs from 58 individuals of the South of France (Nice Bone Collection, Nice, France) were studied. Three measurements of the femoral head were taken: the vertical head diameter (VHD), the transversal head diameter (THD) and the head circumference (HC). The results show that: (i) there is no statistical difference between the right and left femurs for each of the three measurements (VHD, THD and HC). Therefore we arbitrarily chose to use the measures from the right femurs (N=58) to pursue our experiments; (ii) the measurements of the femoral head are similar to those of contemporary American populations; (iii) the dimensions of the femoral head place the measurements of the French population somewhere between Germany or Croatia, and Spain; (iv) there is no significant secular trend (in contrast with the femoral neck diameter); (v) the femoral head measurement as a single variable is useful for sex determination: a 96.5% rate of accuracy was obtained using THD and HC measurements with the artificial neural network; and a 94.8% rate of accuracy using VHD, both with the discriminant analysis and the neural network.

  20. Turbidity Current Head Mixing

    Science.gov (United States)

    Hernandez, David; Sanchez, Miguel Angel; Medina, Pablo

    2010-05-01

    A laboratory experimental set - up for studying the behaviour of sediment in presence of a turbulent field with zero mean flow is compared with the behaviour of turbidity currents [1] . Particular interest is shown on the initiation of sediment motion and in the sediment lift - off. The behaviour of the turbidity current in a flat ground is compared with the zero mean flow oscilating grid generated turbulence as when wave flow lifts off suspended sediments [2,3]. Some examples of the results obtained with this set-up relating the height of the head of the turbidity current to the equilibrium level of stirred lutoclines are shown. A turbulent velocity u' lower than that estimated by the Shield diagram is required to start sediment motion. The minimum u' required to start sediment lift - off, is a function of sediment size, cohesivity and resting time. The lutocline height depends on u', and the vorticity at the lutocline seems constant for a fixed sediment size [1,3]. Combining grid stirring and turbidty current head shapes analyzed by means of advanced image analysis, sediment vertical fluxes and settling speeds can be measured [4,5]. [1] D. Hernandez Turbulent structure of turbidity currents and sediment transport Ms Thesis ETSECCPB, UPC. Barcelona 2009. [2] A. Sánchez-Arcilla; A. Rodríguez; J.C. Santás; J.M. Redondo; V. Gracia; R. K'Osyan; S. Kuznetsov; C. Mösso. Delta'96 Surf-zone and nearshore measurements at the Ebro Delta. A: International Conference on Coastal Research through large Scale Experiments (Coastal Dynamics '97). University of Plymouth, 1997, p. 186-187. [3] P. Medina, M. A. Sánchez and J. M. Redondo. Grid stirred turbulence: applications to the initiation of sediment motion and lift-off studies Physics and Chemistry of the Earth, Part B: Hydrology, Oceans and Atmosphere. 26, Issue 4, 2001, Pages 299-304 [4] M.O. Bezerra, M. Diez, C. Medeiros, A. Rodriguez, E. Bahia., A. Sanchez-Arcilla and J.M. Redondo. Study on the influence of waves on

  1. From hybrid swarms to swarms of hybrids

    Science.gov (United States)

    The introgression of modern humans (Homo sapiens) with Neanderthals 40,000 YBP after a half-million years of separation, may have led to the best example of a hybrid swarm on earth. Modern trade and transportation in support of the human hybrids has continued to introduce additional species, genotyp...

  2. The Hybrid Museum: Hybrid Economies of Meaning

    DEFF Research Database (Denmark)

    Vestergaard, Vitus

    2013-01-01

    this article shows that there are two different museum mindsets where the second mindset leans towards participatory practices. It is shown how a museum can support a hybrid economy of meaning that builds on both a user generated economy of meaning and an institutional economy of meaning and adds value to both....... Such a museum is referred to as a hybrid museum....

  3. Hydraulic Hybrid Vehicles

    Science.gov (United States)

    EPA and the United Parcel Service (UPS) have developed a hydraulic hybrid delivery vehicle to explore and demonstrate the environmental benefits of the hydraulic hybrid for urban pick-up and delivery fleets.

  4. Hybrid Management in Hospitals

    DEFF Research Database (Denmark)

    Byrkjeflot, Haldor; Jespersen, Peter Kragh

    2010-01-01

    Artiklen indeholder et litteraturbaseret studium af ledelsesformer i sygehuse, hvor sundhedsfaglig ledelse og generel ledelse mikses til hybride ledelsesformer......Artiklen indeholder et litteraturbaseret studium af ledelsesformer i sygehuse, hvor sundhedsfaglig ledelse og generel ledelse mikses til hybride ledelsesformer...

  5. Abusive Head Trauma (Shaken Baby Syndrome)

    Science.gov (United States)

    ... Your 1- to 2-Year-Old Abusive Head Trauma (Shaken Baby Syndrome) KidsHealth > For Parents > Abusive Head ... babies tend to cry the most. How These Injuries Happen Abusive head trauma results from injuries caused ...

  6. Heads Up: Concussion in Youth Sports

    Medline Plus

    Full Text Available ... Learn More about the Brain and How it Works Order Free Copies of CDC's “Heads Up” Educational ... Up! Prevent Concussions Prevent Head Injuries Sports Safety Students Play Safe Youth Sports Safety PROMOTIONAL MATERIALS "Heads ...

  7. Head Lice: Treatment Frequently Asked Questions (FAQs)

    Science.gov (United States)

    ... kill head lice? Which medicine is best? Is mayonnaise effective for treating head lice? CDC does not ... to determine if suffocation of head lice with mayonnaise, olive oil, margarine, butter, or similar substances is ...

  8. Type III restriction-modification enzymes: a historical perspective.

    Science.gov (United States)

    Rao, Desirazu N; Dryden, David T F; Bheemanaik, Shivakumara

    2014-01-01

    Restriction endonucleases interact with DNA at specific sites leading to cleavage of DNA. Bacterial DNA is protected from restriction endonuclease cleavage by modifying the DNA using a DNA methyltransferase. Based on their molecular structure, sequence recognition, cleavage position and cofactor requirements, restriction-modification (R-M) systems are classified into four groups. Type III R-M enzymes need to interact with two separate unmethylated DNA sequences in inversely repeated head-to-head orientations for efficient cleavage to occur at a defined location (25-27 bp downstream of one of the recognition sites). Like the Type I R-M enzymes, Type III R-M enzymes possess a sequence-specific ATPase activity for DNA cleavage. ATP hydrolysis is required for the long-distance communication between the sites before cleavage. Different models, based on 1D diffusion and/or 3D-DNA looping, exist to explain how the long-distance interaction between the two recognition sites takes place. Type III R-M systems are found in most sequenced bacteria. Genome sequencing of many pathogenic bacteria also shows the presence of a number of phase-variable Type III R-M systems, which play a role in virulence. A growing number of these enzymes are being subjected to biochemical and genetic studies, which, when combined with ongoing structural analyses, promise to provide details for mechanisms of DNA recognition and catalysis.

  9. Resin Catalyst Hybrids

    Institute of Scientific and Technical Information of China (English)

    S. Asaoka

    2005-01-01

    @@ 1Introduction: What are resin catalyst hybrids? There are typically two types of resin catalyst. One is acidic resin which representative is polystyrene sulfonic acid. The other is basic resin which is availed as metal complex support. The objective items of this study on resin catalyst are consisting of pellet hybrid, equilibrium hybrid and function hybrid of acid and base,as shown in Fig. 1[1-5].

  10. Mesoscale hybrid calibration artifact

    Science.gov (United States)

    Tran, Hy D.; Claudet, Andre A.; Oliver, Andrew D.

    2010-09-07

    A mesoscale calibration artifact, also called a hybrid artifact, suitable for hybrid dimensional measurement and the method for make the artifact. The hybrid artifact has structural characteristics that make it suitable for dimensional measurement in both vision-based systems and touch-probe-based systems. The hybrid artifact employs the intersection of bulk-micromachined planes to fabricate edges that are sharp to the nanometer level and intersecting planes with crystal-lattice-defined angles.

  11. Calculus III essentials

    CERN Document Server

    REA, Editors of

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Calculus III includes vector analysis, real valued functions, partial differentiation, multiple integrations, vector fields, and infinite series.

  12. Genetic analysis of agro-morphological traits in promising hybrids of sunflower (Helianthus annuus L.

    Directory of Open Access Journals (Sweden)

    Maryam GOLABADI

    2015-11-01

    Full Text Available The main objective underlying sunflower breeding programs is to develop high-yielding productive F1 hybrid cultivars. This study was conducted to investigate the genetic control of some agro-morphological traits of new sunflower F1 hybrids. For this purpose, fourteen inbred lines of sunflower were crossed with three male sterile inbred lines. Their hybrids (14 hybrids were then evaluated against three control cultivars. The data thus obtained were analyzed using the nested model (North Carolina Design І as a completely randomized block design (CRBD with four replications. Analysis of variance showed that the hybrids were significantly different in all the traits studied, except for head and stem diameters. From among the hybrids evaluated, Cms19 × Rn1-81 was found to have the highest seed yield and oil content. Cluster analysis classified the hybrids into four different groups. Genetic analysis showed that days to maturity, seed weight, and oil content (% were under the additive gene action. Breeding strategies based on selection could be suggested for the improvement of these traits. Head angle, head diameter, seed yield, and oil yield were under the dominance gene action; breeding based on hybridization methods is, therefore, proposed for these traits. Finally, both additive and dominance gene actions were observed to play important roles in the genetic control of plant height and stem diameter.

  13. Homoploid hybrid expectations

    Science.gov (United States)

    Homoploid hybrid speciation occurs when a stable, fertile, and reproductively isolated lineage results from hybridization between two distinct species without a change in ploidy level. Reproductive isolation between a homoploid hybrid species and its parents is generally attained via chromosomal re...

  14. Hybrid armature projectile

    Science.gov (United States)

    Hawke, Ronald S.; Asay, James R.; Hall, Clint A.; Konrad, Carl H.; Sauve, Gerald L.; Shahinpoor, Mohsen; Susoeff, Allan R.

    1993-01-01

    A projectile for a railgun that uses a hybrid armature and provides a seed block around part of the outer surface of the projectile to seed the hybrid plasma brush. In addition, the hybrid armature is continuously vaporized to replenish plasma in a plasma armature to provide a tandem armature and provides a unique ridge and groove to reduce plasama blowby.

  15. Intraply Hybrid Composite Design

    Science.gov (United States)

    Chamis, C. C.; Sinclair, J. H.

    1986-01-01

    Several theoretical approaches combined in program. Intraply hybrid composites investigated theoretically and experimentally at Lewis Research Center. Theories developed during investigations and corroborated by attendant experiments used to develop computer program identified as INHYD (Intraply Hybrid Composite Design). INHYD includes several composites micromechanics theories, intraply hybrid composite theories, and integrated hygrothermomechanical theory. Equations from theories used by program as appropriate for user's specific applications.

  16. Hybrid quantum information processing

    Energy Technology Data Exchange (ETDEWEB)

    Furusawa, Akira [Department of Applied Physics, School of Engineering, The University of Tokyo (Japan)

    2014-12-04

    I will briefly explain the definition and advantage of hybrid quantum information processing, which is hybridization of qubit and continuous-variable technologies. The final goal would be realization of universal gate sets both for qubit and continuous-variable quantum information processing with the hybrid technologies. For that purpose, qubit teleportation with a continuousvariable teleporter is one of the most important ingredients.

  17. Return of the talking heads

    DEFF Research Database (Denmark)

    Reinecke Hansen, Kenneth; Bro, Peter; Andersson, Ralf

    2016-01-01

    The present article suggests that the brief history of Western television news dramaturgy can be expounded as three major waves: from the early days of the talking heads in the studio, over the narrativization of the field report to a (re-)current studio- and field-based talking heads format....... In order to analyze the latest development entering the third wave, we propose a theoretically based dramaturgical model for the television news item. The analysis concludes that, with the current ‘return’ of the talking heads format, the pre-produced and pre-packaged bulletin program about past events...

  18. Anaphylaxis Due to Head Injury

    Directory of Open Access Journals (Sweden)

    Bruner, Heather C.

    2015-05-01

    Full Text Available Both anaphylaxis and head injury are often seen in the emergency department, but they are rarely seen in combination. We present a case of a 30-year-old woman who presented with anaphylaxis with urticaria and angioedema following a minor head injury. The patient responded well to intramuscular epinephrine without further complications or airway compromise. Prior case reports have reported angioedema from hereditary angioedema during dental procedures and maxillofacial surgery, but there have not been any cases of first-time angioedema or anaphylaxis due to head injury. [West J Emerg Med. 2015;16(3:435–437.

  19. Boxing-related head injuries.

    Science.gov (United States)

    Jayarao, Mayur; Chin, Lawrence S; Cantu, Robert C

    2010-10-01

    Fatalities in boxing are most often due to traumatic brain injury that occurs in the ring. In the past 30 years, significant improvements in ringside and medical equipment, safety, and regulations have resulted in a dramatic reduction in the fatality rate. Nonetheless, the rate of boxing-related head injuries, particularly concussions, remains unknown, due in large part to its variability in clinical presentation. Furthermore, the significance of repeat concussions sustained when boxing is just now being understood. In this article, we identify the clinical manifestations, pathophysiology, and management of boxing-related head injuries, and discuss preventive strategies to reduce head injuries sustained by boxers.

  20. Genotyping the Heading Date of Male-Sterile Rice Line Ⅱ-32A

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Ⅱ-32A, an elite male-sterile line of rice (Oryza sativa L.), has been widely used for the production of hybrid rice seed in China. Heading date in most combinations using Ⅱ-32A shows transgressive inheritance or similarity to the latter parent, but the genotype of Ⅱ-32A with respect to major genes for heading time is unknown. This limits the further exploitation of this sterile line in breeding and hybrid seed production. Using a number of major gene heading date isogenic lines and heading date QTL near-isogenic lines, we genetically analyzed Ⅱ-32B under both long- and short-day conditions. We show that Ⅱ-32B carries two photoperiod-sensitive genes, E1 and E3, a recessive late-heading gene, ef-1, and a photoperiod-sensitive allele, Se-1u. In addition we identified in Ⅱ-32B a recessive inhibitor for E1 or Se-1n and other modified photoperiod-sensitive genes. The heading-date constitution of Ⅱ-32A was determined to be E1e2E3Se-1Uef-1i-Se-1.

  1. The hydrogen hybrid option

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.R.

    1993-10-15

    The energy efficiency of various piston engine options for series hybrid automobiles are compared with conventional, battery powered electric, and proton exchange membrane (PEM) fuel cell hybrid automobiles. Gasoline, compressed natural gas (CNG), and hydrogen are considered for these hybrids. The engine and fuel comparisons are done on a basis of equal vehicle weight, drag, and rolling resistance. The relative emissions of these various fueled vehicle options are also presented. It is concluded that a highly optimized, hydrogen fueled, piston engine, series electric hybrid automobile will have efficiency comparable to a similar fuel cell hybrid automobile and will have fewer total emissions than the battery powered vehicle, even without a catalyst.

  2. Supportive care in early rehabilitation for advanced-stage radiated head and neck cancer patients

    NARCIS (Netherlands)

    Leeuw, J.A.M. de; Berg, M.G. van den; Achterberg, T. van; Merkx, M.A.W.

    2013-01-01

    Objective To investigate the health-related quality of life (HRQoL) and supportive follow-up care needs 1 month posttreatment for patients with advanced-stage (stage III or IV) radiated head and neck cancer (HNC) who were treated with curative intent. Study Design An exploratory, descriptive analysi

  3. Continuous Hyperfractionated Accelerated Radiation Therapy In Head And Neck Cancers- A Pilot Study

    Directory of Open Access Journals (Sweden)

    Thejaswini B

    2014-09-01

    Conclusion:CHART achieves good locoregional response in stages III and IV of head and neck cancer. The acute mucosal reactions were within acceptable limits. The compliance to the treatment was good. [Natl J Med Res 2014; 4(3.000: 218-221

  4. Evaluation of the traumatic coma data bank computed tomography classification for severe head injury

    NARCIS (Netherlands)

    Vos, P E; van Voskuilen, A C; Beems, T; Krabbe, P F; Vogels, O J

    2004-01-01

    This study determines the interrater and intrarater reliability of the Traumatic Coma Data Bank (TCDB) computed tomography (CT) scan classification for severe head injury. This classification grades the severity of the injury as follows: I = normal, II = diffuse injury, III = diffuse injury with swe

  5. Zero torque gear head wrench

    Science.gov (United States)

    Mcdougal, A. R.; Norman, R. M. (Inventor)

    1976-01-01

    A gear head wrench particularly suited for use in applying torque to bolts without transferring torsional stress to bolt-receiving structures is introduced. The wrench is characterized by a coupling including a socket, for connecting a bolt head with a torque multiplying gear train, provided within a housing having an annulus concentrically related to the socket and adapted to be coupled with a spacer interposed between the bolt head and the juxtaposed surface of the bolt-receiving structure for applying a balancing counter-torque to the spacer as torque is applied to the bolt head whereby the bolt-receiving structure is substantially isolated from torsional stress. As a result of the foregoing, the operator of the wrench is substantially isolated from any forces which may be imposed.

  6. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... type your comment or suggestion into the following text box: Comment: E-mail: Area code: Phone no: ... Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging ( ...

  7. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... it may cause some medical devices to malfunction. Most orthopedic implants pose no risk, but you should ... copied to a CD. Currently, MRI is the most sensitive imaging test of the head (particularly the ...

  8. Head, Neck, and Oral Cancer

    Science.gov (United States)

    ... a bright light and a mirror: Remove any dentures Look and feel inside the lips and the ... Early treatment may well be the key to complete recovery. Head, Neck & Oral Cancer Facts The information ...

  9. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... The teddy bear denotes child-specific content. Related Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging (MRI) ...

  10. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... medically necessary. MRI may not always distinguish between cancer tissue and fluid, known as edema . MRI typically ... Brain Tumors Radiation Therapy for Head and Neck Cancer Others : American Stroke Association National Stroke Association top ...

  11. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... medically necessary. MRI may not always distinguish between cancer tissue and fluid, known as edema . MRI typically ... Brain Tumors Radiation Therapy for Head and Neck Cancer Others : American Stroke Association National Stroke Association top ...

  12. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... or headphones during the exam. MRI scanners are air-conditioned and well-lit. Music may be played ... the limitations of MRI of the Head? High-quality images are assured only if you are able ...

  13. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... the head uses a powerful magnetic field, radio waves and a computer to produce detailed pictures of ... the body being imaged, send and receive radio waves, producing signals that are detected by the coils. ...

  14. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... Us News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging ( ... if possible, or removed prior to the MRI scan. Because they can interfere with the magnetic field ...

  15. New Russian science head named

    CERN Multimedia

    Levitin, C

    2000-01-01

    Ilya Klebanov, a deputy prime minister, has been appointed the country's new head of industrial and scientific policy. He will control the new Ministry for Industry, Science and Technologies (4 paragraphs).

  16. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... technologist if you have any devices or metal in your body. Guidelines about eating and drinking before ... imaging test of the head (particularly the brain) in routine clinical practice. top of page What are ...

  17. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... or potentially pose a risk, depending on their nature and the strength of the MRI magnet. Many ... is positioned around the head. If a contrast material will be used in the MRI exam, a ...

  18. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... a computer to produce detailed pictures of the brain and other cranial structures that are clearer and ... sensitive imaging test of the head (particularly the brain) in routine clinical practice. top of page What ...

  19. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... head is performed for a number of abrupt onset or long-standing symptoms. It can help diagnose ... often within less than 30 minutes from the onset of symptoms. Risks The MRI examination poses almost ...

  20. Montessori Head Start Implementation Brief.

    Science.gov (United States)

    Clifford, Alcillia; Kahn, David

    1995-01-01

    Discusses the use of the Montessori method in Head Start programs, focusing on educational environment, teacher training, parent involvement, and funding. Outlines the phased implementation of a Montessori program and provides a list of Montessori publications and organizations. (MDM)

  1. Flat Head Syndrome (Positional Plagiocephaly)

    Science.gov (United States)

    ... symmetrical, but for a variety of reasons the asymmetry becomes less apparent as well. For example, in ... a flattened head does not affect a child's brain growth or cause developmental delays or brain damage. ...

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... digital cloud server. Currently, MRI is the most sensitive imaging test of the head (particularly the brain) ... contrast material in patients with very poor kidney function. Careful assessment of kidney function before considering a ...

  3. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... Brain Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain Tumors Images related to ...

  4. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... is not harmful, but it may cause some medical devices to malfunction. Most orthopedic implants pose no ... Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that physicians use to diagnose medical conditions. ...

  5. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... a computer to produce detailed pictures of the brain and other cranial structures that are clearer and ... sensitive imaging test of the head (particularly the brain) in routine clinical practice. top of page What ...

  6. Heater head for stirling engine

    Science.gov (United States)

    Corey, John A.

    1985-07-09

    A monolithic heater head assembly which augments cast fins with ceramic inserts which narrow the flow of combustion gas and obtains high thermal effectiveness with the assembly including an improved flange design which gives greater durability and reduced conduction loss.

  7. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... of the head uses a powerful magnetic field, radio waves and a computer to produce detailed pictures ... medical conditions. MRI uses a powerful magnetic field, radio frequency pulses and a computer to produce detailed ...

  8. challenges facing child headed households

    African Journals Online (AJOL)

    Mugumbate

    This research employed qualitative methods to establish the daily experiences ... family support systems that view children as society's future and as an .... children's decision-making in 30 child-headed .... fetching water from nearby boreholes.

  9. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... page Additional Information and Resources RTAnswers.org : Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...

  10. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... page Additional Information and Resources RTAnswers.org : Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...

  11. Nutritional status, food intake, and dysphagia in long-term survivors with head and neck cancer treated with chemoradiotherapy: A cross-sectional study

    NARCIS (Netherlands)

    Berg, M.G.A. van den; Rütten, H.; Rasmussen-Conrad, E.L.; Knuijt, S.; Takes, R.P.; Herpen, C.M.L. van; Wanten, G.J.A.; Kaanders, J.H.A.M.; Merkx, M.A.W.

    2014-01-01

    BACKGROUND: The aim of this study was to evaluate nutritional status, food intake, and dysphagia in long-term head and neck cancer survivors. METHODS: Thirty-two patients with stage III-IV head and neck cancer treated by chemoradiotherapy were invited to evaluate nutritional status (malnutrition, re

  12. Factors affecting the germination of hybrid rose achenes

    NARCIS (Netherlands)

    Vries, De D.P.; Dubois, L.A.M.

    2015-01-01

    The smooth germination of mature Hybrid rose achenes is hampered by (i) hardseededness (HS), (ii) primary dormancy (PD) and (iii) germination polymorphism (GP). HS is owing to the hard pericarp. PD is, in principle, a natural phenomenon that protects the seeds from precocious germination. For ger

  13. Factors affecting the germination of hybrid rose achenes

    NARCIS (Netherlands)

    Vries, De D.P.; Dubois, L.A.M.

    2015-01-01

    The smooth germination of mature Hybrid rose achenes is hampered by (i) hardseededness (HS), (ii) primary dormancy (PD) and (iii) germination polymorphism (GP). HS is owing to the hard pericarp. PD is, in principle, a natural phenomenon that protects the seeds from precocious germination. For ger

  14. Chemotaxis of bio-hybrid multiple bacteria-driven microswimmers

    Science.gov (United States)

    Zhuang, Jiang; Sitti, Metin

    2016-08-01

    In this study, in a bio-hybrid microswimmer system driven by multiple Serratia marcescens bacteria, we quantify the chemotactic drift of a large number of microswimmers towards L-serine and elucidate the associated collective chemotaxis behavior by statistical analysis of over a thousand swimming trajectories of the microswimmers. The results show that the microswimmers have a strong heading preference for moving up the L-serine gradient, while their speed does not change considerably when moving up and down the gradient; therefore, the heading bias constitutes the major factor that produces the chemotactic drift. The heading direction of a microswimmer is found to be significantly more persistent when it moves up the L-serine gradient than when it travels down the gradient; this effect causes the apparent heading preference of the microswimmers and is the crucial reason that enables the seemingly cooperative chemotaxis of multiple bacteria on a microswimmer. In addition, we find that their chemotactic drift velocity increases superquadratically with their mean swimming speed, suggesting that chemotaxis of bio-hybrid microsystems can be enhanced by designing and building faster microswimmers. Such bio-hybrid microswimmers with chemotactic steering capability may find future applications in targeted drug delivery, bioengineering, and lab-on-a-chip devices.

  15. Chemotaxis of bio-hybrid multiple bacteria-driven microswimmers

    Science.gov (United States)

    Zhuang, Jiang; Sitti, Metin

    2016-01-01

    In this study, in a bio-hybrid microswimmer system driven by multiple Serratia marcescens bacteria, we quantify the chemotactic drift of a large number of microswimmers towards L-serine and elucidate the associated collective chemotaxis behavior by statistical analysis of over a thousand swimming trajectories of the microswimmers. The results show that the microswimmers have a strong heading preference for moving up the L-serine gradient, while their speed does not change considerably when moving up and down the gradient; therefore, the heading bias constitutes the major factor that produces the chemotactic drift. The heading direction of a microswimmer is found to be significantly more persistent when it moves up the L-serine gradient than when it travels down the gradient; this effect causes the apparent heading preference of the microswimmers and is the crucial reason that enables the seemingly cooperative chemotaxis of multiple bacteria on a microswimmer. In addition, we find that their chemotactic drift velocity increases superquadratically with their mean swimming speed, suggesting that chemotaxis of bio-hybrid microsystems can be enhanced by designing and building faster microswimmers. Such bio-hybrid microswimmers with chemotactic steering capability may find future applications in targeted drug delivery, bioengineering, and lab-on-a-chip devices. PMID:27555465

  16. Hybridization and extinction.

    Science.gov (United States)

    Todesco, Marco; Pascual, Mariana A; Owens, Gregory L; Ostevik, Katherine L; Moyers, Brook T; Hübner, Sariel; Heredia, Sylvia M; Hahn, Min A; Caseys, Celine; Bock, Dan G; Rieseberg, Loren H

    2016-08-01

    Hybridization may drive rare taxa to extinction through genetic swamping, where the rare form is replaced by hybrids, or by demographic swamping, where population growth rates are reduced due to the wasteful production of maladaptive hybrids. Conversely, hybridization may rescue the viability of small, inbred populations. Understanding the factors that contribute to destructive versus constructive outcomes of hybridization is key to managing conservation concerns. Here, we survey the literature for studies of hybridization and extinction to identify the ecological, evolutionary, and genetic factors that critically affect extinction risk through hybridization. We find that while extinction risk is highly situation dependent, genetic swamping is much more frequent than demographic swamping. In addition, human involvement is associated with increased risk and high reproductive isolation with reduced risk. Although climate change is predicted to increase the risk of hybridization-induced extinction, we find little empirical support for this prediction. Similarly, theoretical and experimental studies imply that genetic rescue through hybridization may be equally or more probable than demographic swamping, but our literature survey failed to support this claim. We conclude that halting the introduction of hybridization-prone exotics and restoring mature and diverse habitats that are resistant to hybrid establishment should be management priorities.

  17. Spoof Plasmon Hybridization

    CERN Document Server

    Zhang, Jingjing; Luo, Yu; Shen, Xiaopeng; Maier, Stefan A; Cui, Tie Jun

    2016-01-01

    Plasmon hybridization between closely spaced nanoparticles yields new hybrid modes not found in individual constituents, allowing for the engineering of resonance properties and field enhancement capabilities of metallic nanostructure. Experimental verifications of plasmon hybridization have been thus far mostly limited to optical frequencies, as metals cannot support surface plasmons at longer wavelengths. Here, we introduce the concept of 'spoof plasmon hybridization' in highly conductive metal structures and investigate experimentally the interaction of localized surface plasmon resonances (LSPR) in adjacent metal disks corrugated with subwavelength spiral patterns. We show that the hybridization results in the splitting of spoof plasmon modes into bonding and antibonding resonances analogous to molecular orbital rule and plasmonic hybridization in optical spectrum. These hybrid modes can be manipulated to produce enormous field enhancements (larger than 5000) by tuning the separation between disks or alte...

  18. Analytical modelling of soccer heading

    Indian Academy of Sciences (India)

    Zahari Taha; Mohd Hasnun Arif Hassan; Iskandar Hasanuddin

    2015-08-01

    Heading occur frequently in soccer games and studies have shown that repetitive heading of the soccer ball could result in degeneration of brain cells and lead to mild traumatic brain injury. This study proposes a two degree-of-freedom linear mathematical model to study the impact of the soccer ball on the brain. The model consists of a mass–spring–damper system, in which the skull, the brain and the soccer ball are modelled as a mass and the neck modelled as a spring–damper system. The proposed model was compared with previous dynamic model for soccer ball-to-head impact. Moreover, it was also validated against drop ball experiment on an instrumented dummy skull and also compared with head acceleration data from previous studies. Comparison shows that our proposed model is capable of describing both the skull and brain accelerations qualitatively and quantitatively. This study shows that a simple linear mathematical model can be useful in giving a preliminary insight on the kinematics of human skull and brain during a ball-to-head impact. The model can be used to investigate the important parameters during soccer heading that affect the brain displacement and acceleration, thus providing better understanding of the mechanics behind it.

  19. Marine Fish Hybridization

    KAUST Repository

    He, Song

    2017-04-01

    Natural hybridization is reproduction (without artificial influence) between two or more species/populations which are distinguishable from each other by heritable characters. Natural hybridizations among marine fishes were highly underappreciated due to limited research effort; it seems that this phenomenon occurs more often than is commonly recognized. As hybridization plays an important role in biodiversity processes in the marine environment, detecting hybridization events and investigating hybridization is important to understand and protect biodiversity. The first chapter sets the framework for this disseration study. The Cohesion Species Concept was selected as the working definition of a species for this study as it can handle marine fish hybridization events. The concept does not require restrictive species boundaries. A general history and background of natural hybridization in marine fishes is reviewed during in chapter as well. Four marine fish hybridization cases were examed and documented in Chapters 2 to 5. In each case study, at least one diagnostic nuclear marker, screened from among ~14 candidate markers, was found to discriminate the putative hybridizing parent species. To further investigate genetic evidence to support the hybrid status for each hybrid offspring in each case, haploweb analysis on diagnostic markers (nuclear and/or mitochondrial) and the DAPC/PCA analysis on microsatellite data were used. By combining the genetic evidences, morphological traits, and ecological observations together, the potential reasons that triggered each hybridization events and the potential genetic/ecology effects could be discussed. In the last chapter, sequences from 82 pairs of hybridizing parents species (for which COI barcoding sequences were available either on GenBank or in our lab) were collected. By comparing the COI fragment p-distance between each hybridizing parent species, some general questions about marine fish hybridization were discussed: Is

  20. Anomalia de Classe III

    OpenAIRE

    2014-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Introdução: A anomalia de classe III, é uma má oclusão que afeta os indivíduos psicologicamente, pois hoje em dia, a estética é socialmente valorizada. Deste modo, o diagnóstico deve ser executado precocemente para que os indivíduos portadores desta anomalia, possam ser acompanhados desde criança, pelos profissionais área da Medicina...

  1. Ghost Head Nebula

    Science.gov (United States)

    1999-01-01

    Looking like a colorful holiday card, a new image from NASA's Hubble Space Telescope reveals a vibrant green and red nebula far from Earth. The image of NGC 2080, taken by Hubble's Wide Field and Planetary Camera 2, designed and built by NASA's Jet Propulsion Laboratory, Pasadena, Calif., is available online at http://www.jpl.nasa.gov/images/wfpc . Images like this help astronomers investigate star formation in nebulas. NGC 2080, nicknamed 'The Ghost Head Nebula,' is one of a chain of star-forming regions lying south of the 30 Doradus nebula in the Large Magellanic Cloud. 30 Doradus is the largest star-forming complex in the local group of galaxies. This 'enhanced color' picture is composed of three narrow-band-filter images obtained by Hubble on March 28, 2000. The red and blue light come from regions of hydrogen gas heated by nearby stars. The green light on the left comes from glowing oxygen. The energy to illuminate the green light is supplied by a powerful stellar wind, a stream of high-speed particles coming from a massive star just outside the image. The central white region is a combination of all three emissions and indicates a core of hot, massive stars in this star-formation region. Intense emission from these stars has carved a bowl-shaped cavity in surrounding gas. In the white region, the two bright areas (the 'eyes of the ghost') - named A1 (left) and A2 (right) -- are very hot, glowing 'blobs' of hydrogen and oxygen. The bubble in A1 is produced by the hot, intense radiation and powerful stellar wind from one massive star. A2 contains more dust and several hidden, massive stars. The massive stars in A1 and A2 must have formed within the last 10,000 years, since their natal gas shrouds are not yet disrupted by the powerful radiation of the newborn stars. The Space Telescope Science Institute is operated by the Association of Universities for Research in Astronomy, Inc., for NASA, under contract with the Goddard Space Flight Center, Greenbelt, Md. The

  2. Stability constants of La(III), Pr(III), Nd(III), Sm(III), Gd(III), Tb(III) and Dy(III) complexes with N-(2-hydroxyphenyl) p-toluene sulphonamide

    Energy Technology Data Exchange (ETDEWEB)

    Chopra, S.C.; Mathur, K.C. (Jodhpur Univ. (India). Dept. of Chemistry)

    1981-01-01

    The dissociation constants of the ligand and stability constants of La(III), Pr(III), Nd(III), Sm(III), Gd(III), Tb(III) and Dy(III) complexes with N-(2-hydroxyphenyl) p-toluene sulphonamide have been determined potentiometrically using Calvin-Bjerrum pH titration technique at 30 +- 1deg C and ..mu.. = 0.1 M (NaClO/sub 4/) in aqueous medium. The stability constants of these metal complexes are found to follow the order Dy > Tb > Gd > Sm > Nd > Pr > La.

  3. Backcrosses in interspecific hybridization in sunflower

    Directory of Open Access Journals (Sweden)

    Atlagić Jovanka

    2003-01-01

    Full Text Available When incorporating desirable traits (resistance to causal agents of various diseases from the wild relatives into the cultivated sunflower, some undesirable ones are introduced too (branching, small head diameter, low oil content, etc. To overcome this problem, backcrosses (F1 interspecific hybrids x cultivated sunflower are used, although very often desirable traits are lost in the process. Cytological analysis (meiosis and pollen viability and molecular markers (RAPD were used to estimate what portion of the parental species genome was present in (be interspecific hybrids of the F1 and BC1F1 generations. The results showed that the percentage of irregularities at meiosis increased from F1 to BC1F1 gen. They also indicated the presence of aneuploids and sterility in the cross between the hexaploid species H.rigidus and cultivated sunflower. The genetic distance between the parents was 83%, that between H.rigidus and the F1 hybrid 54 61%, and that between H.annuus and F1 hybrid 70-76%. In the BC1F1 generation, the genetic distance from Hannuus decreased to 58-66% and that from H.rigidus increased to 69-76%.

  4. Study of a thermal drill head for the exploration of subsurface planetary ice layers

    Science.gov (United States)

    Weiss, P.; Yung, K. L.; Ng, T. C.; Kömle, N.; Kargl, G.; Kaufmann, E.

    2008-07-01

    The recently discovered water vapor plumes on Saturn's moon Enceladus, the polar caps of planet Mars and the possible ice volcanism on the Jovian satellites call for suitable techniques to explore deep ice layers of the solar system bodies. This paper presents a novel approach to deliver scientific probes into deeper layers of planetary ice. Several existing locomotion concepts and techniques for such probes are presented. After studying the mathematical framework of the melting locomotion process, melting tests with different head forms were done to evaluate the influence of the head's geometry on the melting process. This work led to a novel concept of a thermal drill head, using heat and mechanical drill in combination to penetrate the ice. We compare the performance of such a hybrid concept versus the melting penetration alone by a mathematical model and tests in ice with a prototype of the melting drill head.

  5. [Illustrations of visceral referred pain. "Head-less" Head's zones].

    Science.gov (United States)

    Henke, C; Beissner, F

    2011-04-01

    Reviewing anatomical, physiological and neurological standard literature for illustrations of referred visceral pain only one type of illustration can frequently be found, which is referred to as Treves and Keith. In fact, the original illustration as a model for most current pictures stems from the German edition of Sir Frederick Treves' famous book "Surgical Applied Anatomy" from 1914, which was reillustrated for didactical reasons for the German readership. While neither Treves and Keith nor the German illustrator Otto Kleinschmidt ever published any work on referred pain this illustration must have been adapted or copied from older sources by the illustrator. Therefore the comprehensive systematic original works before 1914 were reviewed, namely those of Sir Henry Head and Sir James Mackenzie. Due to the name of the phenomenon in the German literature of Head's zones, the illustrations were expected to be based mainly on Head's work. However, a comparison of all available illustrations led to the conclusion that Kleinschmidt chiefly used information from Mackenzie as a model for his illustration. Due to the inexact reproduction of Mackenzie's work by the illustrator some important features were lost that had been reported by the original authors. These include the phenomenon of Head's maximum points, which nowadays has fallen into oblivion.Therefore current charts, based on the illustration by Kleinschmidt from 1914, lack experimental evidence and appear to be a simplification of the observational results of both Head's and Mackenzie's original systematic works.

  6. A systematic literature review of pediculosis due to head lice in the Pacific Island Countries and Territories: what country specific research on head lice is needed?

    Science.gov (United States)

    Speare, Rick; Harrington, Humpress; Canyon, Deon; Massey, Peter D

    2014-06-24

    Lack of guidelines on control of pediculosis in the Solomon Islands led to a search for relevant evidence on head lice in the Pacific Island Countries and Territories (PICTs). The aim of this search was to systematically evaluate evidence in the peer reviewed literature on pediculosis due to head lice (Pediculus humanus var capitis) in the 22 PICTs from the perspective of its value in informing national guidelines and control strategies. PubMed, Web of Science, CINAHL and Scopus were searched using the terms (pediculosis OR head lice) AND each of the 22 PICTs individually. PRISMA methodology was used. Exclusion criteria were: i) not on topic; ii) publications on pediculosis not relevant to the country of the particular search; iii) in grey literature. Of 24 publications identified, only 5 were included. Four related to treatment and one to epidemiology. None contained information relevant to informing national guidelines. Current local evidence on head lice in the PICTs is minimal and totally inadequate to guide any recommendations for treatment or control. We recommend that local research is required to generate evidence on: i) epidemiology; ii) knowledge, attitudes and practices of health care providers and community members; iii) efficacy of local commercially available pharmaceutical treatments and local customary treatments; iv) acceptability, accessibility and affordability of available treatment strategies; and iv) appropriate control strategies for families, groups and institutions. We also recommend that operational research be done by local researchers based in the PICTs, supported by experienced head lice researchers, using a two way research capacity building model.

  7. Population III Hypernovae

    CERN Document Server

    Smidt, Joseph; Even, Wesley; Wiggins, Brandon; Johnson, Jarrett L; Fryer, Chris L

    2014-01-01

    Population III supernovae have been of growing interest of late for their potential to directly probe the properties of the first stars, particularly the most energetic events that are visible near the edge of the observable universe. But until now, hypernovae, the unusually energetic Type Ib/c supernovae that are sometimes associated with gamma-ray bursts, have been overlooked as cosmic lighthouses at the highest redshifts. In this, the latest of a series of studies on Population III supernovae, we present numerical simulations of 25 - 50 M$_{\\odot}$ hypernovae and their light curves done with the Los Alamos RAGE and SPECTRUM codes. We find that they will be visible at z = 10 - 15 to the James Webb Space Telescope (JWST) and z = 4 - 5 to the Wide-Field Infrared Survey Telescope (WFIRST), tracing star formation rates in the first galaxies and at the end of cosmological reionization. If, however, the hypernova crashes into a dense shell ejected by its progenitor, a superluminous event will occur that may be se...

  8. POPULATION III HYPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Smidt, Joseph; Whalen, Daniel J. [T-2, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Wiggins, Brandon K. [Department of Physics and Astronomy, Brigham Young University, Provo, UT 84602 (United States); Even, Wesley; Fryer, Chris L. [CCS-2, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Johnson, Jarrett L., E-mail: dwhalen1999@gmail.com [XTD-PRI, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2014-12-20

    Population III supernovae have been of growing interest of late for their potential to directly probe the properties of the first stars, particularly the most energetic events that are visible near the edge of the observable universe. Until now, hypernovae, the unusually energetic Type Ib/c supernovae that are sometimes associated with gamma-ray bursts, have been overlooked as cosmic beacons at the highest redshifts. In this, the latest of a series of studies on Population III supernovae, we present numerical simulations of 25-50 M {sub ☉} hypernovae and their light curves done with the Los Alamos RAGE and SPECTRUM codes. We find that they will be visible at z = 10-15 to the James Webb Space Telescope and z = 4-5 to the Wide-Field Infrared Survey Telescope, tracing star formation rates in the first galaxies and at the end of cosmological reionization. If, however, the hypernova crashes into a dense shell ejected by its progenitor, it is expected that a superluminous event will occur that may be seen at z ∼ 20 in the first generation of stars.

  9. Toward Head-Up and Head-Worn Displays for Equivalent Visual Operations

    Science.gov (United States)

    Prinzel, Lawrence J., III; Arthur, Jarvis J.; Bailey, Randall E.; Shelton, Kevin J.; Kramer, Lynda J.; Jones, Denise R.; Williams, Steven P.; Harrison, Stephanie J.; Ellis, Kyle K.

    2015-01-01

    A key capability envisioned for the future air transportation system is the concept of equivalent visual operations (EVO). EVO is the capability to achieve the safety of current-day Visual Flight Rules (VFR) operations and maintain the operational tempos of VFR irrespective of the weather and visibility conditions. Enhanced Flight Vision Systems (EFVS) offer a path to achieve EVO. NASA has successfully tested EFVS for commercial flight operations that has helped establish the technical merits of EFVS, without reliance on natural vision, to runways without category II/III ground-based navigation and lighting requirements. The research has tested EFVS for operations with both Head-Up Displays (HUDs) and "HUD equivalent" Head-Worn Displays (HWDs). The paper describes the EVO concept and representative NASA EFVS research that demonstrate the potential of these technologies to safely conduct operations in visibilities as low as 1000 feet Runway Visual Range (RVR). Future directions are described including efforts to enable low-visibility approach, landing, and roll-outs using EFVS under conditions as low as 300 feet RVR.

  10. Heads Up: Concussion in Youth Sports

    Medline Plus

    Full Text Available ... in Spanish [Podcast: 1:27 minutes] Send a Health eCard Heads Up! Prevent Concussions Prevent Head Injuries ... in Spanish [Podcast: 1:27 minutes] Send a Health eCard Heads Up! Prevent Concussions Prevent Head Injuries ...

  11. Heading for a fall? Management of head injury in infants.

    LENUS (Irish Health Repository)

    Williamson, M

    2010-09-01

    Head injury is one of the commonest reasons for infants (< 1 year) to attend the Emergency Department (ED). Clinical management varies considerably and concern about non accidental injury results in a high admission rate in some hospitals. Information was obtained on 103 children under one year of age presenting to the ED with head injury in a prospective study. The average age was 6.7 months and 57% of patients were male. Twenty eight babies had skull x rays with 1 skull fracture diagnosed. None required CT brain scan. Ninety eight (94%) were discharged home from the ED. There were no unplanned returns, readmissions or adverse events. The incidence of traumatic brain injury in children under one year of age presenting with head injury is low and the majority can be safely discharged home.

  12. Bistable Head Positioning Arm Latch

    Science.gov (United States)

    Wasson, Ken; Endo, Juro; Mita, Masahiro; Abelein, Nathan

    A simple, low cost, yet effective device has been developed for immobilizing the head-arm assembly in a disk drive or similar mechanism during power-off conditions. The latching scheme also provides a consistent means of releasing the head-arm assembly from the immobilized position upon power up of the disk drive. The latch uses no electrical power in either immobilized or released state. This design is immune to extreme torque and linear shock forces applied to the disk drive case. The latch system can use the energy stored in the spinning disks to drive the head-arm assembly toward a safe position while simultaneously arming the latch mechanism to secure the head-arm assembly in the safe position upon arrival. A low energy five msec pulse of current drives the latch from one state to the other. Solenoids as presently used in latch mechanisms are bulky, expensive, have variable force characteristics, and often generate contaminants. The latch described in this paper is expected to replace such solenoids. It may also replace small magnet latches, which have limited latch force and apply unwanted torque to a proximate head positioning arm.

  13. Magnetic head having a wear-resistant layer, and method of manufacturing such a magnetic head

    NARCIS (Netherlands)

    Dirne, F.W.A.; Zieren, V.; Broese van Groenou, A.; Oorschot, L.F.M. van; Lasinski, P.; Jongh, M. de; Roozeboom, F.

    2002-01-01

    Magnetic head having a head face (5) and comprising a head structure composed of thin layers and provided with a transducing element (E11), in which different materials occurring in different areas are present in the head face. The head face is provided with a first layer (31) of a material which is

  14. Henkin and Hybrid Logic

    DEFF Research Database (Denmark)

    Blackburn, Patrick Rowan; Huertas, Antonia; Manzano, Maria;

    2014-01-01

    Leon Henkin was not a modal logician, but there is a branch of modal logic that has been deeply influenced by his work. That branch is hybrid logic, a family of logics that extend orthodox modal logic with special proposition symbols (called nominals) that name worlds. This paper explains why...... Henkin’s techniques are so important in hybrid logic. We do so by proving a completeness result for a hybrid type theory called HTT, probably the strongest hybrid logic that has yet been explored. Our completeness result builds on earlier work with a system called BHTT, or basic hybrid type theory...... is due to the first-order perspective, which lies at the heart of Henin’s best known work and hybrid logic....

  15. Fast ejendom III

    DEFF Research Database (Denmark)

    Munk-Hansen, Carsten

    Bogen er det tredje bind af tre planlagte bind om fast ejendom: I Overdragelsen, II Bolighandlen og III Ejerbeføjelsen. Fremstillingens giver et grundigt overblik over centrale områder af en omfattende regulering af fast ejendom, med angivelse af litteratur, hvor læseren kan søge yderligere...... oplysning. En ejer af fast ejendom er på særdeles mange områder begrænset i sin råden sammenlignet med ejeren af et formuegode i almindelighed. Fremstillingen tager udgangspunkt i ejerens perspektiv (fremfor samfundets eller myndighedernes). Både den privatretlige og offentligretlige regulering behandles......, eksempelvis ejendomsdannelsen, servitutter, naboretten, hævd, zoneinddelingen, den fysiske planlægning, beskyttelse af natur, beskyttelse af kultur, forurening fra fast ejendom, erstatning for forurening, jordforurening, ekspropriation, byggeri og adgang til fast ejendom....

  16. Ammonium diphosphitoindate(III

    Directory of Open Access Journals (Sweden)

    Farida Hamchaoui

    2013-04-01

    Full Text Available The crystal structure of the title compound, NH4[In(HPO32], is built up from InIII cations (site symmetry 3m. adopting an octahedral environment and two different phosphite anions (each with site symmetry 3m. exhibiting a triangular–pyramidal geometry. Each InO6 octahedron shares its six apices with hydrogen phosphite groups. Reciprocally, each HPO3 group shares all its O atoms with three different metal cations, leading to [In(HPO32]− layers which propagate in the ab plane. The ammonium cation likewise has site symmetry 3m.. In the structure, the cations are located between the [In(HPO32]− layers of the host framework. The sheets are held together by hydrogen bonds formed between the NH4+ cations and the O atoms of the framework.

  17. Oxymatrinium tetrachloridoferrate(III

    Directory of Open Access Journals (Sweden)

    Xiong He

    2012-02-01

    Full Text Available The asymmetric unit of the title compound, (C15H25N2O2[FeCl4], contains a tetrachloridoferrate(III anion and a oxymatrinium cation [oxymatrine is (4R,7aS,13aR,13bR,13cS-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one 4-oxide]. The conformation of oxymatrine is similar to that of matrine with one ring having a half-chair conformation, while the others have chair conformations. Chiral chains of cations along the c axis are formed by O—H...O hydrogen bonds.

  18. III.— Documents

    OpenAIRE

    2014-01-01

    III/1 inventaire de l’orangerie du château d’Ivry, 1770 • Inventaire après décès du marquis de Béringhen (extrait), AN M.C. LXXXVIII, 723, 28 février 1770 « [f° 113 v°] Dudit jour samedi seize du présent mois de juin huit heures du matin à même requête qualité et preuve que dessus, ainsi que le tout a été ci-devant établi, va être par les conseillers du roi notaires au Châtelet de Paris [f° 114 r°] soussignés procédé à la continuation du présent inventaire de la manière et ainsi qu’il suit. S...

  19. Pseudo Class III malocclusion.

    Science.gov (United States)

    Al-Hummayani, Fadia M

    2016-04-01

    The treatment of deep anterior crossbite is technically challenging due to the difficulty of placing traditional brackets with fixed appliances. This case report represents a none traditional treatment modality to treat deep anterior crossbite in an adult pseudo class III malocclusion complicated by severely retruded, supraerupted upper and lower incisors. Treatment was carried out in 2 phases. Phase I treatment was performed by removable appliance "modified Hawley appliance with inverted labial bow," some modifications were carried out to it to suit the presented case. Positive overbite and overjet was accomplished in one month, in this phase with minimal forces exerted on the lower incisors. Whereas, phase II treatment was performed with fixed appliances (braces) to align teeth and have proper over bite and overjet and to close posterior open bite, this phase was accomplished within 11 month.

  20. The role of MR imaging in staging femoral head osteonecrosis

    Energy Technology Data Exchange (ETDEWEB)

    Zibis, Aristidis H. [Department of Orthopaedic Surgery, Medical School, University of Thessaly, 22 Papakyriazi Street, Larissa 41222 (Greece); Karantanas, Apostolos H. [Department of Radiology, University Hospital of Heraklion, University of Crete Medical School, Heraklion, Crete 71110 (Greece); Roidis, Nikolaos T. [Department of Orthopaedic Surgery, Medical School, University of Thessaly, 22 Papakyriazi Street, Larissa 41222 (Greece); Hantes, Michael E. [Department of Orthopaedic Surgery, Medical School, University of Thessaly, 22 Papakyriazi Street, Larissa 41222 (Greece); Argiri, Paraskevi [CT-MRI Department, Larissa General Hospital, Larissa 41221 (Greece); Moraitis, Theofanis [Department of Orthopaedic Surgery, Medical School, University of Thessaly, 22 Papakyriazi Street, Larissa 41222 (Greece); Malizos, Konstantinos N. [Department of Orthopaedic Surgery, Medical School, University of Thessaly, 22 Papakyriazi Street, Larissa 41222 (Greece)]. E-mail: kmalizos@otenet.gr

    2007-07-15

    Reliability, accuracy and prognostic value of any classification system are important in evaluation and treatment of femoral head osteonecrosis. The purpose of the present study was to correlate the plain radiographs with MRI in femoral head osteonecrosis. Between 2000 and 2005, 115 hips (72 patients) were evaluated and classified according to the ARCO classification criteria with the use of plain radiographs and additional application of MRI. Classification was performed by consensus between a musculoskeletal radiologist and an orthopaedic surgeon. Sensitivity (SEN), specificity (SP), positive (PPV) and negative (NPV) predictive value of X-rays were estimated. According to MRI, 17 hips were classified as stage I, 25 as stage II, 48 as stage III and 25 as stage IV. The SEN, SP, PPV and NPV of plain radiographs were for stage II 88%, 90.5%, 78.6% and 95%; for stage III 79.2% 82%, 80.8% and 87.2%; for stage IV 76%, 100%, 100% and 90.9%, respectively. The agreement between plain radiographs and MRI was 80.6% for staging the disease, 71.2% for recording the location of the osteonecrotic lesion, 67.1% for evaluating the size of the lesion, 79.2% for the presence of collapse of the articular surface and 56.3% for the degree of collapse. In conclusion, the ARCO classification could miss important information in stages II and III, where treatment aims at preservation of the hip joint integrity. The results of the present study suggest that MRI should be incorporated in the classification of osteonecrosis (stages II and III), to add accuracy and prognostic value.

  1. BSA Hybrid Synthesized Polymer

    Institute of Scientific and Technical Information of China (English)

    Zong Bin LIU; Xiao Pei DENG; Chang Sheng ZHAO

    2006-01-01

    Bovine serum albumin (BSA), a naturally occurring biopolymer, was regarded as a polymeric material to graft to an acrylic acid (AA)-N-vinyl pyrrolidone (NVP) copolymer to form a biomacromolecular hybrid polymer. The hybrid polymer can be blended with polyethersulfone (PES) to increase the hydrophilicity of the PES membrane, which suggested that the hybrid polymer might have a wide application in the modification of biomaterials.

  2. Hybrid Action Systems

    DEFF Research Database (Denmark)

    Ronkko, Mauno; Ravn, Anders P.

    1997-01-01

    a differential action, which allows differential equations as primitive actions. The extension allows us to model hybrid systems with both continuous and discrete behaviour. The main result of this paper is an extension of such a hybrid action system with parallel composition. The extension does not change...... the original meaning of the parallel composition, and therefore also the ordinary action systems can be composed in parallel with the hybrid action systems....

  3. HYBRID VEHICLE CONTROL SYSTEM

    Directory of Open Access Journals (Sweden)

    V. Dvadnenko

    2016-06-01

    Full Text Available The hybrid vehicle control system includes a start–stop system for an internal combustion engine. The system works in a hybrid mode and normal vehicle operation. To simplify the start–stop system, there were user new possibilities of a hybrid car, which appeared after the conversion. Results of the circuit design of the proposed system of basic blocks are analyzed.

  4. Nanoscale Organic Hybrid Electrolytes

    KAUST Repository

    Nugent, Jennifer L.

    2010-08-20

    Nanoscale organic hybrid electrolytes are composed of organic-inorganic hybrid nanostructures, each with a metal oxide or metallic nanoparticle core densely grafted with an ion-conducting polyethylene glycol corona - doped with lithium salt. These materials form novel solvent-free hybrid electrolytes that are particle-rich, soft glasses at room temperature; yet manifest high ionic conductivity and good electrochemical stability above 5V. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Hybrid radiator cooling system

    Science.gov (United States)

    France, David M.; Smith, David S.; Yu, Wenhua; Routbort, Jules L.

    2016-03-15

    A method and hybrid radiator-cooling apparatus for implementing enhanced radiator-cooling are provided. The hybrid radiator-cooling apparatus includes an air-side finned surface for air cooling; an elongated vertically extending surface extending outwardly from the air-side finned surface on a downstream air-side of the hybrid radiator; and a water supply for selectively providing evaporative cooling with water flow by gravity on the elongated vertically extending surface.

  6. Reduced meiotic fitness in hybrids with heterozygosity for heterochromatin in the speciating Mus terricolor complex

    Indian Academy of Sciences (India)

    Tikaram Sharma; Amit Bardhan; Min Bahadur

    2003-03-01

    Mus terricolor I, II and III are the three chromosomal species which differ in stable autosomal short-arm heterochromatin variations established in homozygous condition. Analysis of meiosis in the laboratorygenerated F1 male hybrids from crosses (both ways) between M. terricolor I and II and between M. terricolor I and III shows high frequencies of pairing abnormalities at pachytene. The backcross (N3 generation) male hybrids between M. terricolor I and II have meiotic abnormalities as in the F1 male hybrids, though to a lesser extent. They show difference in pairing abnormalities in the different karyotypic forms; the backcross hybrids heterozygous for the heterochromatic short arms have more anomalies compared to the homokaryotypic hybrids. This suggests a negative influence of the heterochromatin heterozygosity in meiotic pairing. The results indicate a role for heterochromatin variations in the development of a reproductive barrier in the speciating M. terricolor complex.

  7. Hybrid Unifying Variable Supernetwork Model

    Institute of Scientific and Technical Information of China (English)

    LIU; Qiang; FANG; Jin-qing; LI; Yong

    2015-01-01

    In order to compare new phenomenon of topology change,evolution,hybrid ratio and network characteristics of unified hybrid network theoretical model with unified hybrid supernetwork model,this paper constructed unified hybrid variable supernetwork model(HUVSM).The first layer introduces a hybrid ratio dr,the

  8. Large Unifying Hybrid Supernetwork Model

    Institute of Scientific and Technical Information of China (English)

    LIU; Qiang; FANG; Jin-qing; LI; Yong

    2015-01-01

    For depicting multi-hybrid process,large unifying hybrid network model(so called LUHNM)has two sub-hybrid ratios except dr.They are deterministic hybrid ratio(so called fd)and random hybrid ratio(so called gr),respectively.

  9. Clinical Applications of FDG PET and PET/CT in Head and Neck Cancer

    Directory of Open Access Journals (Sweden)

    Akram Al-Ibraheem

    2009-01-01

    Full Text Available 18F-FDG PET plays an increasing role in diagnosis and management planning of head and neck cancer. Hybrid PET/CT has promoted the field of molecular imaging in head and neck cancer. This modality is particular relevant in the head and neck region, given the complex anatomy and variable physiologic FDG uptake patterns. The vast majority of 18F-FDG PET and PET/CT applications in head and neck cancer related to head and neck squamous cell carcinoma. Clinical applications of 18F-FDG PET and PET/CT in head and neck cancer include diagnosis of distant metastases, identification of synchronous 2nd primaries, detection of carcinoma of unknown primary and detection of residual or recurrent disease. Emerging applications are precise delineation of the tumor volume for radiation treatment planning, monitoring treatment, and providing prognostic information. The clinical role of 18F-FDG PET/CT in N0 disease is limited which is in line with findings of other imaging modalities. MRI is usually used for T staging with an intense discussion concerning the preferable imaging modality for regional lymph node staging as PET/CT, MRI, and multi-slice spiral CT are all improving rapidly. Is this review, we summarize recent literature on 18F-FDG PET and PET/CT imaging of head and neck cancer.

  10. Hybrid Rocket Technology

    National Research Council Canada - National Science Library

    Sankaran Venugopal; K K Rajesh; V Ramanujachari

    2011-01-01

    With their unique operational characteristics, hybrid rockets can potentially provide safer, lower-cost avenues for spacecraft and missiles than the current solid propellant and liquid propellant systems...

  11. Hybrid FOSS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Armstrong researchers are continuing their efforts to further develop FOSS technologies. A hybrid FOSS technique (HyFOSS) employs conventional continuous grating...

  12. Wheelchair control by head motion

    Directory of Open Access Journals (Sweden)

    Pajkanović Aleksandar

    2013-01-01

    Full Text Available Electric wheelchairs are designed to aid paraplegics. Unfortunately, these can not be used by persons with higher degree of impairment, such as quadriplegics, i.e. persons that, due to age or illness, can not move any of the body parts, except of the head. Medical devices designed to help them are very complicated, rare and expensive. In this paper a microcontroller system that enables standard electric wheelchair control by head motion is presented. The system comprises electronic and mechanic components. A novel head motion recognition technique based on accelerometer data processing is designed. The wheelchair joystick is controlled by the system’s mechanical actuator. The system can be used with several different types of standard electric wheelchairs. It is tested and verified through an experiment performed within this paper.

  13. Outcome of Radial Head Arthroplasty in Comminuted Radial Head Fractures: Short and Midterm Results

    Directory of Open Access Journals (Sweden)

    Moghaddam

    2016-02-01

    Full Text Available Background Comminuted radial head fractures are often associated with secondary injuries and elbow instability. Objectives The aim of this retrospective study was to evaluate how well the modular metallic radial head implant EVOLVE® prosthesis restores functional range of motion (ROM and stability of the elbow in acute care. Patients and Methods Eighty-five patients with comminuted radial head fractures and associated injuries received treatment with an EVOLVE® prosthesis between May 2001 and November 2009. Seventy-five patients were available for follow-up. On average, patients were followed for 41.5 months (33.0: 4.0 - 93.0. Outcome assessment was done on the basis of pain, ROM, strength, radiographic findings, and functional rating scores such as Broberg and Morrey, the Mayo elbow performance index (MEPI, and disabilities of the arm, shoulder and hand (DASH. Our study is currently the largest analysis of clinical outcome of a modular radial head replacement in the literature. Results Overall, there were 2 (2.7% Mason II fractures, 21 (28% Mason III fractures, and 52 (69.3% Mason IV fractures. Arbeitsgemeinschaft fur osteosynthesefragen (AO classification was also determined. Of the 85 patients in our study, 75 were available for follow-up. Follow-up averaged 41.5 months (range, 4 - 93 months. Average scores for the cohort were as follows: Morrey, 85.7 (median 90.2; range 44.4 - 100; MEPI, 83.3 (85.0; 40.0 - 100; and DASH 26.1 points (22.5; 0.0 - 75.8. Mean flexion/extension in the affected joint was 125.7°/16.5°/0° in comparison to the noninjured side 138.5°/0°/1.2°. Mean pronation/supination was 70.5°/0°/67.1° in comparison to the noninjured side 83.6°/0°/84.3°. Handgrip strength of the injured compared to the non-injured arm was 78.8%. The following complications were also documented: 58 patients had periprosthetic radioluceny shown to be neither clinically significant nor relevant according to evaluated scores; 26 patients

  14. Semiconducting III-V compounds

    CERN Document Server

    Hilsum, C; Henisch, Heinz R

    1961-01-01

    Semiconducting III-V Compounds deals with the properties of III-V compounds as a family of semiconducting crystals and relates these compounds to the monatomic semiconductors silicon and germanium. Emphasis is placed on physical processes that are peculiar to III-V compounds, particularly those that combine boron, aluminum, gallium, and indium with phosphorus, arsenic, and antimony (for example, indium antimonide, indium arsenide, gallium antimonide, and gallium arsenide).Comprised of eight chapters, this book begins with an assessment of the crystal structure and binding of III-V compounds, f

  15. From hybrid swarms to swarms of hybrids

    Science.gov (United States)

    Stohlgren, Thomas J.; Szalanski, Allen L; Gaskin, John F.; Young, Nicholas E.; West, Amanda; Jarnevich, Catherine S.; Tripodi, Amber

    2015-01-01

    Science has shown that the introgression or hybridization of modern humans (Homo sapiens) with Neanderthals up to 40,000 YBP may have led to the swarm of modern humans on earth. However, there is little doubt that modern trade and transportation in support of the humans has continued to introduce additional species, genotypes, and hybrids to every country on the globe. We assessed the utility of species distributions modeling of genotypes to assess the risk of current and future invaders. We evaluated 93 locations of the genus Tamarix for which genetic data were available. Maxent models of habitat suitability showed that the hybrid, T. ramosissima x T. chinensis, was slightly greater than the parent taxa (AUCs > 0.83). General linear models of Africanized honey bees, a hybrid cross of Tanzanian Apis mellifera scutellata and a variety of European honey bee including A. m. ligustica, showed that the Africanized bees (AUC = 0.81) may be displacing European honey bees (AUC > 0.76) over large areas of the southwestern U.S. More important, Maxent modeling of sub-populations (A1 and A26 mitotypes based on mDNA) could be accurately modeled (AUC > 0.9), and they responded differently to environmental drivers. This suggests that rapid evolutionary change may be underway in the Africanized bees, allowing the bees to spread into new areas and extending their total range. Protecting native species and ecosystems may benefit from risk maps of harmful invasive species, hybrids, and genotypes.

  16. Head First 2D Geometry

    CERN Document Server

    Fallow), Stray

    2009-01-01

    Having trouble with geometry? Do Pi, The Pythagorean Theorem, and angle calculations just make your head spin? Relax. With Head First 2D Geometry, you'll master everything from triangles, quads and polygons to the time-saving secrets of similar and congruent angles -- and it'll be quick, painless, and fun. Through entertaining stories and practical examples from the world around you, this book takes you beyond boring problems. You'll actually use what you learn to make real-life decisions, like using angles and parallel lines to crack a mysterious CSI case. Put geometry to work for you, and

  17. The Video Head Impulse Test

    Directory of Open Access Journals (Sweden)

    G. M. Halmagyi

    2017-06-01

    Full Text Available In 1988, we introduced impulsive testing of semicircular canal (SCC function measured with scleral search coils and showed that it could accurately and reliably detect impaired function even of a single lateral canal. Later we showed that it was also possible to test individual vertical canal function in peripheral and also in central vestibular disorders and proposed a physiological mechanism for why this might be so. For the next 20 years, between 1988 and 2008, impulsive testing of individual SCC function could only be accurately done by a few aficionados with the time and money to support scleral search-coil systems—an expensive, complicated and cumbersome, semi-invasive technique that never made the transition from the research lab to the dizzy clinic. Then, in 2009 and 2013, we introduced a video method of testing function of each of the six canals individually. Since 2009, the method has been taken up by most dizzy clinics around the world, with now close to 100 refereed articles in PubMed. In many dizzy clinics around the world, video Head Impulse Testing has supplanted caloric testing as the initial and in some cases the final test of choice in patients with suspected vestibular disorders. Here, we consider seven current, interesting, and controversial aspects of video Head Impulse Testing: (1 introduction to the test; (2 the progress from the head impulse protocol (HIMPs to the new variant—suppression head impulse protocol (SHIMPs; (3 the physiological basis for head impulse testing; (4 practical aspects and potential pitfalls of video head impulse testing; (5 problems of vestibulo-ocular reflex gain calculations; (6 head impulse testing in central vestibular disorders; and (7 to stay right up-to-date—new clinical disease patterns emerging from video head impulse testing. With thanks and appreciation we dedicate this article to our friend, colleague, and mentor, Dr Bernard Cohen of Mount Sinai Medical School, New York, who

  18. Head kinematics during shaking associated with abusive head trauma.

    Science.gov (United States)

    Lintern, T O; Puhulwelle Gamage, N T; Bloomfield, F H; Kelly, P; Finch, M C; Taberner, A J; Nash, M P; Nielsen, P M F

    2015-09-18

    Abusive head trauma (AHT) is a potentially fatal result of child abuse but the mechanisms of injury are controversial. To address the hypothesis that shaking alone is sufficient to elicit the injuries observed, effective computational and experimental models are necessary. This paper investigates the use of a coupled rigid-body computational modelling framework to reproduce in vivo shaking kinematics in AHT. A sagittal plane OpenSim computational model of a lamb was developed and used to interpret biomechanical data from in vivo shaking experiments. The acceleration of the head during shaking was used to provide in vivo validation of the associated computational model. Results of this study demonstrated that peak accelerations occurred when the head impacted the torso and produced acceleration magnitudes exceeding 200ms(-)(2). The computational model demonstrated good agreement with the experimental measurements and was shown to be able to reproduce the high accelerations that occur during impact. The biomechanical results obtained with the computational model demonstrate the utility of using a coupled rigid-body modelling framework to describe infant head kinematics in AHT.

  19. Vascular endothelial growth factor gene transfection to enhance the repair of avascular necrosis of the femoral head of rabbit

    Institute of Scientific and Technical Information of China (English)

    杨操; 杨述华; 杜靖远; 李进; 许伟华; 熊宇芳

    2003-01-01

    Objective To explore a new method for the therapy of avascular necrosis of the femoral head.Methods The recombinant plasmid pCD-hVEGF165 was mixed with collagen and was implanted in the necrotic femoral head. The expression of vascular endothelial growth factor (VEGF) was examined by RNA dot hybridization and immunohistochemical techniques. Repair of the femoral head was observed by histological and histomorphometric analysis.Results The expression of VEGF was detected in the femoral head transfected with the VEGF gene. The femoral head transfected with the VEGF gene showed a significant increase in angiogenesis 2 and 4 weeks after gene transfection and a significant increase in bone formation 6 and 8 weeks after gene transfection on histomorphometric analysis (P<0.01).Conclusions Transfection of the VEGF gene enhances bone tissue angiogenesis. Repair of osteonecrosis could be accelerated accordingly, thus providing a potential method for therapy of osteonecrosis.

  20. Biomolecule/nanomaterial hybrid systems for nanobiotechnology.

    Science.gov (United States)

    Tel-Vered, Ran; Yehezkeli, Omer; Willner, Itamar

    2012-01-01

    The integration of biomolecules with metallic or semiconductor nanoparticles or carbon nanotubes yields new hybrid nanostructures of unique features that combine the properties of the biomolecules and of the nano-elements. These unique features of the hybrid biomolecule/nanoparticle systems provide the basis for the rapid development of the area of nanobiotechnology. Recent advances in the implementation of hybrid materials consisting of biomolecules and metallic nanoparticles or semiconductor quantum dots will be discussed. The following topics will be exemplified: (i) The electrical wiring of redox enzymes with electrodes by means of metallic nanoparticles or carbon nanotubes, and the application of the modified electrodes as amperometric biosensors or for the construction of biofuel cells. (ii) The biocatalytic growth of metallic nanoparticles as a means to construct optical or electrical sensors. (iii) The functionalization of semiconductor quantum dots with biomolecules and the application of the hybrid nanostructures for developing different optical sensors, including intracellular sensor systems. (iv) The use of biomolecule-metallic nanoparticle nanostructures as templates for growing metallic nanowires, and the construction of fuel-driven nano-transporters.

  1. Hybrid Dynamic Network Data Envelopment Analysis

    Directory of Open Access Journals (Sweden)

    Ling Li

    2015-01-01

    Full Text Available Conventional DEA models make no hypothesis concerning the internal operations in a static situation. To open the “black box” and work with dynamic assessment issues synchronously, we put forward a hybrid model for evaluating the relative efficiencies of a set of DMUs over an observed time period with a composite of network DEA and dynamic DEA. We vertically deal with intermediate products between divisions with assignable inputs in the network structure and, horizontally, we extend network structure by means of a dynamic pattern with unrelated activities between two succeeding periods. The hybrid dynamic network DEA model proposed in this paper enables us to (i pry into the internal operations of DEA by another network structure, (ii obtain dynamic change of period efficiency, and (iii gain the overall dynamic efficiency of DMUs over the entire observed periods. We finally illustrate the calculation procedure of the proposed approach by a numerical example.

  2. Hybrid silicon evanescent approach to optical interconnects

    Science.gov (United States)

    Liang, Di; Fang, Alexander W.; Chen, Hui-Wen; Sysak, Matthew N.; Koch, Brian R.; Lively, Erica; Raday, Omri; Kuo, Ying-Hao; Jones, Richard; Bowers, John E.

    2009-06-01

    We discuss the recently developed hybrid silicon evanescent platform (HSEP), and its application as a promising candidate for optical interconnects in silicon. A number of key discrete components and a wafer-scale integration process are reviewed. The motivation behind this work is to realize silicon-based photonic integrated circuits possessing unique advantages of III-V materials and silicon-on-insulator waveguides simultaneously through a complementary metal-oxide semiconductor fabrication process. Electrically pumped hybrid silicon distributed feedback and distributed Bragg reflector lasers with integrated hybrid silicon photodetectors are demonstrated coupled to SOI waveguides, serving as the reliable on-chip single-frequency light sources. For the external signal processing, Mach-Zehnder interferometer modulators are demonstrated, showing a resistance-capacitance-limited, 3 dB electrical bandwidth up to 8 GHz and a modulation efficiency of 1.5 V mm. The successful implementation of quantum well intermixing technique opens up the possibility to realize multiple III-V bandgaps in this platform. Sampled grating DBR devices integrated with electroabsorption modulators (EAM) are fabricated, where the bandgaps in gain, mirror, and EAM regions are 1520, 1440 and 1480 nm, respectively. The high-temperature operation characteristics of the HSEP are studied experimentally and theoretically. An overall characteristic temperature ( T 0) of 51°C, an above threshold characteristic temperature ( T 1) of 100°C, and a thermal impedance ( Z T ) of 41.8°C/W, which agrees with the theoretical prediction of 43.5°C/W, are extracted from the Fabry-Perot devices. Scaling this platform to larger dimensions is demonstrated up to 150 mm wafer diameter. A vertical outgassing channel design is developed to accomplish high-quality III-V epitaxial transfer to silicon in a timely and dimension-independent fashion.

  3. Hybrid CT angiography and quantitative (15)O-water PET for assessment of coronary artery disease

    DEFF Research Database (Denmark)

    Thomassen, Anders; Petersen, Henrik; Diederichsen, Axel C P;

    2013-01-01

    CT angiography (CTA) can rule out significant stenoses with a very high reliability, whereas its ability to confirm significant stenoses is suboptimal. In contrast, measurements of myocardial blood flow (MBF) provide information on the haemodynamic consequences of stenoses. Therefore, a combinati...... of the two might improve diagnostic accuracy. We conducted a head-to-head comparison of CTA, measurement of MBF by (15)O-water PET, and hybrid PET/CTA for the detection of significant coronary artery stenoses....

  4. The Marxist Aspect in Bessie Head's A Question of Power

    Directory of Open Access Journals (Sweden)

    Mohamed Fathi Helaly

    2016-11-01

    Full Text Available South Africa is one country where racial discrimination was widespread. Like the rest of the color-skinned people, colored writers in South Africa are marginalized and denied the right to express their experiences of living in a society riddled with racial inequality and oppression. Marxism is a school of thought that is concerned about the conflict between the dominant powerful classes and the oppressed ones in any given society. According to Marxism, literary texts are viewed as material that can be interpreted within historical contexts. South Africa is a country where the Apartheid System has been dominant. It is a country that has people of different ethnicity: the White, the Black and the Colored who are known as people of mixed race or hybrid. In South Africa colored people are doubly oppressed by their community, as they belong neither to the Black nor to the White. The colored people are marginalized and demeaned to a very degraded status by their society. Bessie Head is a South African female writer who is concerned about the clash between the different classes in her society. In this study the researcher wants to explore the class-struggle of women in general and the hybrid females in particular under the Apartheid System from a Marxist point of view. As a South-African female writer, Head is concerned about the struggle for power between the White and The Black, on the one hand, and between the hybrids on the other. A Question of Power can be seen as an indictment of the governing system in South Africa. It is a system that governs people not as ordinary human beings but according to the color of their skin. It is an autobiographical novel that tells the story of Elizabeth as a women living under the Apartheid System. Elizabeth, the fictional character of Bessie Head, has to suffer greatly as a woman but her suffering as a hybrid is even greater. On the one hand, she is socially marginalized as a female living in a patriarchal

  5. Numerical and experimental analysis of heat transfer in injector plate of hydrogen peroxide hybrid rocket motor

    Science.gov (United States)

    Cai, Guobiao; Li, Chengen; Tian, Hui

    2016-11-01

    This paper is aimed to analyze heat transfer in injector plate of hydrogen peroxide hybrid rocket motor by two-dimensional axisymmetric numerical simulations and full-scale firing tests. Long-time working, which is an advantage of hybrid rocket motor over conventional solid rocket motor, puts forward new challenges for thermal protection. Thermal environments of full-scale hybrid rocket motors designed for long-time firing tests are studied through steady-state coupled numerical simulations of flow field and heat transfer in chamber head. The motor adopts 98% hydrogen peroxide (98HP) oxidizer and hydroxyl-terminated poly-butadiene (HTPB) based fuel as the propellants. Simulation results reveal that flowing liquid 98HP in head oxidizer chamber could cool the injector plate of the motor. The cooling of 98HP is similar to the regenerative cooling in liquid rocket engines. However, the temperature of the 98HP in periphery portion of the head oxidizer chamber is higher than its boiling point. In order to prevent the liquid 98HP from unexpected decomposition, a thermal protection method for chamber head utilizing silica-phenolics annular insulating board is proposed. The simulation results show that the annular insulating board could effectively decrease the temperature of the 98HP in head oxidizer chamber. Besides, the thermal protection method for long-time working hydrogen peroxide hybrid rocket motor is verified through full-scale firing tests. The ablation of the insulating board in oxygen-rich environment is also analyzed.

  6. Components of phenotypic variability for head diameter in sunflower - Helianthus annuus L.

    OpenAIRE

    Hladni Nada; Škorić Dragan; Kraljević-Balalić Marija

    2003-01-01

    Sunflower is the main crop species for the production of edible oil in many countries of the world, including ours. Plant height and head size, form and position on the stem as well as the number of leaves, their size, duration and distribution on the plant all play an important role in defining optimal plant architecture in sunflower hybrids (Škorić, 1975, 1989, 2002). In order to monitor the mode of inheritance and gene effects for head diameter in the F1 and F2 generations, half diallel cr...

  7. Hypersensitive response-like reaction is associated with hybrid necrosis in interspecific crosses between tetraploid wheat and Aegilops tauschii coss.

    Directory of Open Access Journals (Sweden)

    Nobuyuki Mizuno

    Full Text Available BACKGROUND: Hybrid speciation is classified into homoploid and polyploid based on ploidy level. Common wheat is an allohexaploid species that originated from a naturally occurring interploidy cross between tetraploid wheat and diploid wild wheat Aegilops tauschii Coss. Aegilops tauschii provides wide naturally occurring genetic variation. Sometimes its triploid hybrids with tetraploid wheat show the following four types of hybrid growth abnormalities: types II and III hybrid necrosis, hybrid chlorosis, and severe growth abortion. The growth abnormalities in the triploid hybrids could act as postzygotic hybridization barriers to prevent formation of hexaploid wheat. METHODOLOGY/PRINCIPAL FINDINGS: Here, we report on the geographical and phylogenetic distribution of Ae. tauschii accessions inducing the hybrid growth abnormalities and showed that they are widely distributed across growth habitats in Ae. tauschii. Molecular and cytological characterization of the type III necrosis phenotype was performed. The hybrid abnormality causing accessions were widely distributed across growth habitats in Ae. tauschii. Transcriptome analysis showed that a number of defense-related genes such as pathogenesis-related genes were highly up-regulated in the type III necrosis lines. Transmission electron microscope observation revealed that cell death occurred accompanied by generation of reactive oxygen species in leaves undergoing type III necrosis. The reduction of photosynthetic activity occurred prior to the appearance of necrotic symptoms on the leaves exhibiting hybrid necrosis. CONCLUSIONS/SIGNIFICANCE: Taking these results together strongly suggests that an autoimmune response might be triggered by intergenomic incompatibility between the tetraploid wheat and Ae. tauschii genomes in type III necrosis, and that genetically programmed cell death could be regarded as a hypersensitive response-like cell death similar to that observed in Arabidopsis

  8. RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes.

    Directory of Open Access Journals (Sweden)

    Pénélope Legros

    2014-11-01

    Full Text Available Condensin-mediated chromosome condensation is essential for genome stability upon cell division. Genetic studies have indicated that the association of condensin with chromatin is intimately linked to gene transcription, but what transcription-associated feature(s direct(s the accumulation of condensin remains unclear. Here we show in fission yeast that condensin becomes strikingly enriched at RNA Pol III-transcribed genes when Swd2.2 and Sen1, two factors involved in the transcription process, are simultaneously deleted. Sen1 is an ATP-dependent helicase whose orthologue in Saccharomyces cerevisiae contributes both to terminate transcription of some RNA Pol II transcripts and to antagonize the formation of DNA:RNA hybrids in the genome. Using two independent mapping techniques, we show that DNA:RNA hybrids form in abundance at Pol III-transcribed genes in fission yeast but we demonstrate that they are unlikely to faciliate the recruitment of condensin. Instead, we show that Sen1 forms a stable and abundant complex with RNA Pol III and that Swd2.2 and Sen1 antagonize both the interaction of RNA Pol III with chromatin and RNA Pol III-dependent transcription. When Swd2.2 and Sen1 are lacking, the increased concentration of RNA Pol III and condensin at Pol III-transcribed genes is accompanied by the accumulation of topoisomerase I and II and by local nucleosome depletion, suggesting that Pol III-transcribed genes suffer topological stress. We provide evidence that this topological stress contributes to recruit and/or stabilize condensin at Pol III-transcribed genes in the absence of Swd2.2 and Sen1. Our data challenge the idea that a processive RNA polymerase hinders the binding of condensin and suggest that transcription-associated topological stress could in some circumstances facilitate the association of condensin.

  9. Plant characters of broccoli determinants of head production

    Directory of Open Access Journals (Sweden)

    Fernanda Daniela Brandelero

    2016-06-01

    Full Text Available ABSTRACT: The increasing consumption of single-head broccoli is due to several factors, among them there are food production in minimally processing form and the existence of hybrids that adapt to various climates, in addition to the simple harvesting of this typical architecture.This study aimed to identify the most relevant plant characters of broccoli, represented by growth characters, which are determinant in the production and canopy area. The study was conducted in an experimental area in Pato Branco city, PR. The 11 characters were evaluated for 365 plants, spaced with 0.8x0.5m, on a blank experiment. The characters of group 1 (height, number of leaves, stem height, stem diameter were evaluated on the 21 and 58 day after transplanting (DAT, and the leaf area was evaluated on the 17 and 32 DAT. The characters of group 2 were quantity of fresh head mass and canopy area. At the initial stage of cultivation, on the 17 and 21 DAT, variations in the plants characters did not lead toany variation in production. The higher number of leaves and the larger stem diameter on the 58 DAT determined the greater mass of the broccoli heads.

  10. Cardiac hybrid imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gaemperli, Oliver [University Hospital Zurich, Cardiac Imaging, Zurich (Switzerland); University Hospital Zurich, Nuclear Cardiology, Cardiovascular Center, Zurich (Switzerland); Kaufmann, Philipp A. [University Hospital Zurich, Cardiac Imaging, Zurich (Switzerland); Alkadhi, Hatem [University Hospital Zurich, Institute of Diagnostic and Interventional Radiology, Zurich (Switzerland)

    2014-05-15

    Hybrid cardiac single photon emission computed tomography (SPECT)/CT imaging allows combined assessment of anatomical and functional aspects of cardiac disease. In coronary artery disease (CAD), hybrid SPECT/CT imaging allows detection of coronary artery stenosis and myocardial perfusion abnormalities. The clinical value of hybrid imaging has been documented in several subsets of patients. In selected groups of patients, hybrid imaging improves the diagnostic accuracy to detect CAD compared to the single imaging techniques. Additionally, this approach facilitates functional interrogation of coronary stenoses and guidance with regard to revascularization procedures. Moreover, the anatomical information obtained from CT coronary angiography or coronary artery calcium scores (CACS) adds prognostic information over perfusion data from SPECT. The use of cardiac hybrid imaging has been favoured by the dissemination of dedicated hybrid systems and the release of dedicated image fusion software, which allow simple patient throughput for hybrid SPECT/CT studies. Further technological improvements such as more efficient detector technology to allow for low-radiation protocols, ultra-fast image acquisition and improved low-noise image reconstruction algorithms will be instrumental to further promote hybrid SPECT/CT in research and clinical practice. (orig.)

  11. Hybrid intelligent engineering systems

    CERN Document Server

    Jain, L C; Adelaide, Australia University of

    1997-01-01

    This book on hybrid intelligent engineering systems is unique, in the sense that it presents the integration of expert systems, neural networks, fuzzy systems, genetic algorithms, and chaos engineering. It shows that these new techniques enhance the capabilities of one another. A number of hybrid systems for solving engineering problems are presented.

  12. A Hybrid Imagination

    DEFF Research Database (Denmark)

    Jamison, Andrew; Christensen, Steen Hyldgaard; Botin, Lars

    contexts, or sites, for mixing scientific knowledge and technical skills from different fields and social domains into new combinations, thus fostering what the authors term a “hybrid imagination”. Such a hybrid imagination is especially important today, as a way to counter the competitive and commercial...

  13. Hybrid trajectory spaces

    NARCIS (Netherlands)

    Collins, P.J.

    2005-01-01

    In this paper, we present a general framework for describing and studying hybrid systems. We represent the trajectories of the system as functions on a hybrid time domain, and the system itself by its trajectory space, which is the set of all possible trajectories. The trajectory space is given a na

  14. Editorial: Hybrid Systems

    DEFF Research Database (Denmark)

    Olderog, Ernst-Rüdiger; Ravn, Anders Peter

    2007-01-01

    An introduction to three papers in a special issue on Hybrid Systems. These paper were first presented at an IFIP WG 2.2 meeting in Skagen 2005.......An introduction to three papers in a special issue on Hybrid Systems. These paper were first presented at an IFIP WG 2.2 meeting in Skagen 2005....

  15. The Animal Without A Head

    Institute of Scientific and Technical Information of China (English)

    万钧

    2002-01-01

    Have you ever seen an animal with out a head?there is such an animal! it has no tail or legs ,its body is full of holes it eats and breathes but never moves,it lives under water,the water brings the animal air.

  16. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... distinguish between cancer tissue and fluid, known as edema . MRI typically costs more and may take more time to perform than other imaging modalities. top of page Additional Information and Resources RTAnswers.org : Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...

  17. Pediatric head injuries from earthquakes.

    Science.gov (United States)

    Martinez-Lage, Juan F; Almagro, María-José; López-Guerrero, Antonio López; Martínez-Lage Azorín, Carlos

    2012-10-01

    By means of some illustrations, the authors briefly report the effects of some accidental head injuries caused by diverse mechanisms occurring in children. Many of these accidents seem to be preventable, but others are completely unavoidable and escape prevention as the one that is depicted in the cover of this issue.

  18. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... very early stage by mapping the motion of water molecules in the tissue. This water motion, known as diffusion, is impaired by most ... page Additional Information and Resources RTAnswers.org : Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...

  19. Neuroelectromagnetic Forward Head Modeling Toolbox

    Science.gov (United States)

    Acar, Zeynep Akalin; Makeig, Scott

    2014-01-01

    This paper introduces a Neuroelectromagnetic Forward Head Modeling Toolbox (NFT) running under MATLAB (The Mathworks, Inc.) for generating realistic head models from available data (MRI and/or electrode locations) and for computing numerical solutions for the forward problem of electromagnetic source imaging. The NFT includes tools for segmenting scalp, skull, cerebrospinal fluid (CSF) and brain tissues from T1-weighted magnetic resonance (MR) images. The Boundary Element Method (BEM) is used for the numerical solution of the forward problem. After extracting segmented tissue volumes, surface BEM meshes can be generated. When a subject MR image is not available, a template head model can be warped to measured electrode locations to obtain an individualized head model. Toolbox functions may be called either from a graphic user interface compatible with EEGLAB (http://sccn.ucsd.edu/eeglab), or from the MATLAB command line. Function help messages and a user tutorial are included. The toolbox is freely available under the GNU Public License for noncommercial use and open source development. PMID:20457183

  20. Blunt Head Trauma and Headache

    Directory of Open Access Journals (Sweden)

    Ana B Chelse

    2015-04-01

    Full Text Available Investigators from New York Presbyterian Morgan Stanley Children’s Hospital examined whether having an isolated headache following minor blunt head trauma was suggestive of traumatic brain injury (TBI among a large cohort of children 2-18 years of age.

  1. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... very early stage by mapping the motion of water molecules in the tissue. This water motion, known as diffusion, is impaired by most ... the limitations of MRI of the Head? High-quality images are assured only if you are able ...

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... very early stage by mapping the motion of water molecules in the tissue. This water motion, known as diffusion, is impaired by most ... the limitations of MRI of the Head? High-quality images are assured only if you are able ...

  3. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... structures of the brain and can also provide functional information (fMRI) in selected cases. MR images of ... Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain ...

  4. Excision Versus Fixation of the Radial Head: A Comparative Study of the Functional Outcomes of the Two Techniques

    Science.gov (United States)

    Shetty, Sanath Kumar; Shetty, Ashwin; Balan, Bijith; Rai, H.Ravindranath; Hegde, Anoop

    2017-01-01

    Introduction The management of displaced and comminuted radial head fractures has been a matter of debate amongst surgeons for many years. Radial head excision formed the mainstay of surgical management of these injuries. Over the years, there have been improvements in the surgical techniques and availability of better implants and instrumentation techniques, hence, open reduction and internal fixation of these fractures is gaining popularity. Aim To compare the outcome of elbow function between radial head excision and open reduction and internal fixation of the radial head with mini screws of Mason Type II and Type III radial head fractures and to assess the complications that occur in both techniques. Materials and Methods A prospective study was conducted in the Department of Orthopaedic Surgery of Justice K.S.Hegde Charitable hospital. A total of 40 patients between the age group of 30-50 years with Mason Type II and Type III fresh closed radial head fractures were included in the study. Group I consisted of 20 patients who underwent radial head excision and Group II consisted of 20 patients who underwent open reduction and internal fixation with mini screws. Patients were reviewed at postoperative week 3, 6 and 24. Radiographs were taken and functional outcome assessment of the elbow was done during all the follow ups. Elbow physiotherapy was started on postoperative week three. Scoring of elbow function was done as per the Disabilities of the Arm, Shoulder and Hand (DASH) scoring system. Results were tabulated, compared and analysed statistically using the ‘chi-square test’. Results At the end of six months, the patients of the open reduction and internal fixation group had lower DASH scores (4.82±2.73 points) than the radial head excision group (14.23±5.60 points). This inferred that patients who underwent open reduction and internal fixation had better functional outcomes than the excision group. Complications of proximal radial migration was noted

  5. Hybrid reactors. [Fuel cycle

    Energy Technology Data Exchange (ETDEWEB)

    Moir, R.W.

    1980-09-09

    The rationale for hybrid fusion-fission reactors is the production of fissile fuel for fission reactors. A new class of reactor, the fission-suppressed hybrid promises unusually good safety features as well as the ability to support 25 light-water reactors of the same nuclear power rating, or even more high-conversion-ratio reactors such as the heavy-water type. One 4000-MW nuclear hybrid can produce 7200 kg of /sup 233/U per year. To obtain good economics, injector efficiency times plasma gain (eta/sub i/Q) should be greater than 2, the wall load should be greater than 1 MW.m/sup -2/, and the hybrid should cost less than 6 times the cost of a light-water reactor. Introduction rates for the fission-suppressed hybrid are usually rapid.

  6. Hybrid propulsion technology program

    Science.gov (United States)

    1990-01-01

    Technology was identified which will enable application of hybrid propulsion to manned and unmanned space launch vehicles. Two design concepts are proposed. The first is a hybrid propulsion system using the classical method of regression (classical hybrid) resulting from the flow of oxidizer across a fuel grain surface. The second system uses a self-sustaining gas generator (gas generator hybrid) to produce a fuel rich exhaust that was mixed with oxidizer in a separate combustor. Both systems offer cost and reliability improvement over the existing solid rocket booster and proposed liquid boosters. The designs were evaluated using life cycle cost and reliability. The program consisted of: (1) identification and evaluation of candidate oxidizers and fuels; (2) preliminary evaluation of booster design concepts; (3) preparation of a detailed point design including life cycle costs and reliability analyses; (4) identification of those hybrid specific technologies needing improvement; and (5) preperation of a technology acquisition plan and large scale demonstration plan.

  7. Hybrid silica luminescent materials based on lanthanide-containing lyotropic liquid crystal with polarized emission

    Energy Technology Data Exchange (ETDEWEB)

    Selivanova, N.M., E-mail: natsel@mail.ru [Kazan National Research Technological University, 68 Karl Marx Str., Kazan 420015 (Russian Federation); Vandyukov, A.E.; Gubaidullin, A.T. [A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences, 8 Acad. Arbuzov Str., Kazan 420088 (Russian Federation); Galyametdinov, Y.G. [Kazan National Research Technological University, 68 Karl Marx Str., Kazan 420015 (Russian Federation)

    2014-11-14

    This paper represents the template method for synthesis of hybrid silica films based on Ln-containing lyotropic liquid crystal and characterized by efficient luminescence. Luminescence films were prepared in situ by the sol–gel processes. Lyotropic liquid crystal (LLC) mesophases C{sub 12}H{sub 25}O(CH{sub 2}CH{sub 2}O){sub 10}H/Ln(NO{sub 3}){sub 3}·6H{sub 2}O/H{sub 2}O containing Ln (III) ions (Dy, Tb, Eu) were used as template. Polarized optical microscopy, X-ray powder diffraction, and FT-IR-spectroscopy were used for characterization of liquid crystal mesophases and hybrid films. The morphology of composite films was studied by the atomic force microscopy method (AFM). The optical properties of the resulting materials were evaluated. It was found that hybrid silica films demonstrate significant increase of their lifetime in comparison with an LLC system. New effects of linearly polarized emission revealed for Ln-containing hybrid silica films. Polarization in lanthanide-containing hybrid composites indicates that silica precursor causes orientation of emitting ions. - Highlights: • We suggest a new simple approach for creating luminescence hybrid silica films. • Ln-containing hybrid silica films demonstrate yellow, green and red emissions. • Tb(III)-containing hybrid film have a high lifetime. • We report effects of linearly polarized emission in hybrid film.

  8. Porcine head response to blast

    Directory of Open Access Journals (Sweden)

    Jay eShridharani

    2012-05-01

    Full Text Available Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, the mechanisms that cause blast neurotrauma are unknown. Blast neurotrauma research using computational models has been one method to elucidate that response of the brain in blast, and to identify possible mechanical correlates of injury. However, model validation against experimental data is required to ensure that the model output is representative of in vivo biomechanical response. This study exposed porcine subjects to primary blast overpressures generated using a compressed-gas shock tube. Shock tube blasts were directed to the unprotected head of each animal while the lungs and thorax were protected using ballistic protective vests similar to those employed in theater. The test conditions ranged from 110-740 kPa peak incident overpressure with scaled durations from 1.3-6.9 ms and correspond approximately with a 50% injury risk for brain bleeding and apnea in a ferret model scaled to porcine exposure. The bulk head acceleration and the pressure at the surface of the head and in the cranial cavity were measured. Immediately after the blast, 5 of the 20 animals tested were apneic. Three subjects recovered without intervention within thirty seconds and the remaining two recovered within 8 minutes following bagging and administration of the respiratory stimulant doxapram. Gross examination of the brain revealed no indication of bleeding. Intracranial pressures ranged from 80-685 kPa as a result of the blast and were notably lower than the shock tube reflected pressures of 300-2830 kPa, indicating pressure attenuation by the skull up to a factor of 8.4. Peak head accelerations were measured from 385-3845 G’s and were well correlated with peak incident overpressure (R2=0.90. One standard deviation corridors for the surface pressure, intracranial pressure, and head acceleration are presented to provide experimental data for

  9. Kinetics and dynamics of DNA hybridization.

    Science.gov (United States)

    Yin, Yandong; Zhao, Xin Sheng

    2011-11-15

    DNA hybridization, wherein strands of DNA form duplex or larger hybrids through noncovalent, sequence-specific interactions, is one of the most fundamental processes in biology. Developing a better understanding of the kinetic and dynamic properties of DNA hybridization will thus help in the elucidation of molecular mechanisms involved in numerous biochemical processes. Moreover, because DNA hybridization has been widely adapted in biotechnology, its study is invaluable to the development of a range of commercially important processes. In this Account, we examine recent studies of the kinetics and dynamics of DNA hybridization, including (i) intramolecular collision of random coil, single-stranded DNA (ssDNA), (ii) nucleic acid hairpin folding, and (iii) considerations of DNA hybridization from both a global view and a detailed base-by-base view. We also examine the spontaneous single-base-pair flipping in duplex DNA because of its importance to both DNA hybridization and repair. Intramolecular collision of random coil ssDNA, with chemical relaxation times ranging from hundreds of nanoseconds to a few microseconds, is investigated both theoretically and experimentally. The first passage time theory of Szabo, Schulten, and Schulten, which determines the average reaction time of the intrachain collision, was tested. Although it was found to provide an acceptable approximation, a more sophisticated theoretical treatment is desirable. Nucleic acid hairpin folding has been extensively investigated as an important model system of DNA hybridization. The relaxation time of hairpin folding and unfolding strongly depends on the stem length, and it may range from hundreds of microseconds to hundreds of milliseconds. The traditional two-state model has been revised to a multistate model as a result of new experimental observations and theoretical study, and partially folded intermediate states have been introduced to the folding energy landscape. On the other hand, new

  10. PREFACE: Quantum Optics III

    Science.gov (United States)

    Orszag, M.; Retamal, J. C.; Saavedra, C.; Wallentowitz, S.

    2007-06-01

    All the 50 years of conscious pondering did not bring me nearer to an answer to the question `what is light quanta?'. Nowadays, every rascal believes, he knows it, however, he is mistaken. (A Einstein, 1951 in a letter to M Besso) Quantum optics has played a key role in physics in the last several decades. On the other hand, in these early decades of the information age, the flow of information is becoming more and more central to our daily life. Thus, the related fields of quantum information theory as well as Bose-Einstein condensation have acquired tremendous importance in the last couple of decades. In Quantum Optics III, a fusion of these fields appears in a natural way. Quantum Optics III was held in Pucón, Chile, in 27-30 of November, 2006. This beautiful location in the south of Chile is near the lake Villarrica and below the snow covered volcano of the same name. This fantastic environment contributed to a relaxed atmosphere, suitable for informal discussion and for the students to have a chance to meet the key figures in the field. The previous Quantum Optics conferences took place in Santiago, Chile (Quantum Optics I, 2000) and Cozumel, Mexico (Quantum Optics II, 2004). About 115 participants from 19 countries attended and participated in the meeting to discuss a wide variety of topics such as quantum-information processing, experiments related to non-linear optics and squeezing, various aspects of entanglement including its sudden death, correlated twin-photon experiments, light storage, decoherence-free subspaces, Bose-Einstein condensation, discrete Wigner functions and many more. There was a strong Latin-American participation from Argentina, Brazil, Chile, Colombia, Peru, Uruguay, Venezuela and Mexico, as well as from Europe, USA, China, and Australia. New experimental and theoretical results were presented at the conference. In Latin-America a quiet revolution has taken place in the last twenty years. Several groups working in quantum optics and

  11. Soccer heading frequency predicts neuropsychological deficits.

    Science.gov (United States)

    Witol, Adrienne D; Webbe, Frank M

    2003-05-01

    This study investigated the presence of neuropsychological deficits associated with hitting the ball with one's head (heading) during soccer play. A neuro-cognitive test battery was administered to 60 male soccer players, high school, amateur and professional level, and 12 nonplaying control participants. The effects of currently reported heading behavior as well as that of estimated lifetime heading experience on neuropsychological test performance were examined. Players with the highest lifetime estimates of heading had poorer scores on scales measuring attention, concentration, cognitive flexibility and general intellectual functioning. Players' current level of heading was less predictive of neuro-cognitive level. Comparison of individual scores to age-appropriate norms revealed higher probabilities of clinical levels of impairment in players who reported greater lifetime frequencies of heading. Because of the worldwide popularity of the game, continued research is needed to assess the interaction between heading and soccer experience in the development of neuropsychological deficits associated with soccer play.

  12. Humeral head size in shoulder arthroplasty

    DEFF Research Database (Denmark)

    Vaesel, M T; Olsen, Bo Sanderhoff; Søjbjerg, Jens Ole

    1998-01-01

    Changes in kinematics after hemiarthroplasty of the glenohumeral joint were investigated in nine cadaveric specimens. During experiments the influence of the humeral head size on glenohumeral kinematics was evaluated. A modular prosthesis with five different head sizes and press-fit stems was used....... Three-dimensional kinematic measurements during abduction and adduction from 0 degree to 70 degrees showed increased external rotation with increasing head size. Small prosthetic heads translated inferiorly and large prosthetic heads superiorly compared with the intact humeral head. During forced...... anterior and posterior translation the mobility is restricted with increasing head size. This study found that when a press-fit prosthesis is used, it takes 1.25 times the volume of the intact humeral head to reconstruct the kinematics of the glenohumeral joint....

  13. Preschool Facilities - MDC_HeadStart

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — A label (point) feature class of Head Start / Early Head Start/ Delegate Agencies/ Child Care Partnership & Family Day Care Homes Programs location in Miami-Dade...

  14. Heads Up: Concussion in Youth Sports

    Medline Plus

    Full Text Available ... this? Submit Button Connect with HEADS UP & CDC's Injury Center HEADS UP Resources File Formats Help: How ... Disease Control and Prevention , Â National Center for Injury Prevention and Control , Â Division of Unintentional Injury ...

  15. Heads Up: Concussion in Youth Sports

    Medline Plus

    Full Text Available ... Email Address What's this? Submit What's this? Submit Button Concussion in Youth Sports Training course: This page ... Email Address What's this? Submit What's this? Submit Button Connect with HEADS UP & CDC's Injury Center HEADS ...

  16. Hybrid Aluminum and Natural Fiber Composite Structure for Crash Safety Improvement

    Science.gov (United States)

    Helaili, S.; Chafra, M.; Chevalier, Y.

    There is a growing interest on pedestrian's protection in automotive safety standards. Pedestrians head impact is one of the most important tests. In this paper, a hybrid composite structure made from natural fiber and aluminum, which improve the head protection when impact is taken place, is presented. The structure is made from a honeycomb composite made from unidirectional and woven composites and a thin aluminum layer. A head impact model is developed. The number of hexagonal layers is fixed and the thickness of the aluminum layer of the honeycomb structure is varied. The specific absorption energy is then calculated.

  17. Ultrahigh-speed hybrid laser for silicon photonic integrated chips

    DEFF Research Database (Denmark)

    Chung, Il-Sug; Park, Gyeong Cheol; Ran, Qijiang;

    2013-01-01

    and will be 80% in near future. This challenge strongly has motivated replacing electrical interconnects with optical ones even in chip level communications [1]. This chip-level optical interconnects need quite different performance of optoelectronic devices than required for conventional optical communications....... For a light source, the energy consumption per sending a bit is required to be laser diode...... and light-emitting diode (LED) structures have been proposed so far. Our hybrid laser is one of these efforts [2]. The hybrid laser consists of a dielectric reflector, a III-V semiconductor active material, and a high-index-contrast grating (HCG) reflector formed in the silicon layer of a silicon...

  18. Head stabilization in whooping cranes

    Science.gov (United States)

    Kinloch, M.R.; Cronin, T.W.; Olsen, G.H.; Chavez-Ramirez, Felipe

    2005-01-01

    The whooping crane (Grus americana) is the tallest bird in North America, yet not much is known about its visual ecology. How these birds overcome their unusual height to identify, locate, track, and capture prey items is not well understood. There have been many studies on head and eye stabilization in large wading birds (herons and egrets), but the pattern of head movement and stabilization during foraging is unclear. Patterns of head movement and stabilization during walking were examined in whooping cranes at Patuxent Wildlife Research Center, Laurel, Maryland USA. Four whooping cranes (1 male and 3 females) were videotaped for this study. All birds were already acclimated to the presence of people and to food rewards. Whooping cranes were videotaped using both digital and Hi-8 Sony video cameras (Sony Corporation, 7-35 Kitashinagawa, 6-Chome, Shinagawa-ku, Tokyo, Japan), placed on a tripod and set at bird height in the cranes' home pens. The cranes were videotaped repeatedly, at different locations in the pens and while walking (or running) at different speeds. Rewards (meal worms, smelt, crickets and corn) were used to entice the cranes to walk across the camera's view plane. The resulting videotape was analyzed at the University of Maryland at Baltimore County. Briefly, we used a computerized reduced graphic model of a crane superimposed over each frame of analyzed tape segments by means of a custom written program (T. W. Cronin, using C++) with the ability to combine video and computer graphic input. The speed of the birds in analyzed segments ranged from 0.30 m/s to 2.64 m/s, and the proportion of time the head was stabilized ranged from 79% to 0%, respectively. The speed at which the proportion reached 0% was 1.83 m/s. The analyses suggest that the proportion of time the head is stable decreases as speed of the bird increases. In all cases, birds were able to reach their target prey with little difficulty. Thus when cranes are walking searching for food

  19. Revenue Maximizing Head Starts in Contests

    OpenAIRE

    Franke, Jörg; Leininger, Wolfgang; Wasser, Cédric

    2014-01-01

    We characterize revenue maximizing head starts for all-pay auctions and lottery contests with many heterogeneous players. We show that under optimal head starts all-pay auctions revenue-dominate lottery contests for any degree of heterogeneity among players. Moreover, all-pay auctions with optimal head starts induce higher revenue than any multiplicatively biased all-pay auction or lottery contest. While head starts are more effective than multiplicative biases in all-pay auctions, they are l...

  20. Head and Neck Soft Tissue Sarcoma

    OpenAIRE

    Aljabab, A. S.; Nason, R. W.; Kazi, R; Pathak, K. A.

    2011-01-01

    Sarcomas are malignant neoplasms originating from mesodermal tissues and constitute less than 1% of body’s tumors, including those of the head and neck region. 5–15% of adult sarcomas are in the head and neck region (20% from bones and cartilages and 80% in soft tissues). Commonly encountered sarcomas in the head and neck region are - osteosarcoma, rhabdomyosarcoma, malignant fibrous histiocytoma, fibrosarcoma and angiosarcoma. This article reviews the available literature on head and neck sa...

  1. Analysis of fuel cell hybrid locomotives

    Science.gov (United States)

    Miller, Arnold R.; Peters, John; Smith, Brian E.; Velev, Omourtag A.

    Led by Vehicle Projects LLC, an international industry-government consortium is developing a 109 t, 1.2 MW road-switcher locomotive for commercial and military railway applications. As part of the feasibility and conceptual-design analysis, a study has been made of the potential benefits of a hybrid power plant in which fuel cells comprise the prime mover and a battery or flywheel provides auxiliary power. The potential benefits of a hybrid power plant are: (i) enhancement of transient power and hence tractive effort; (ii) regenerative braking; (iii) reduction of capital cost. Generally, the tractive effort of a locomotive at low speed is limited by wheel adhesion and not by available power. Enhanced transient power is therefore unlikely to benefit a switcher locomotive, but could assist applications that require high acceleration, e.g. subway trains with all axles powered. In most cases, the value of regeneration in locomotives is minimal. For low-speed applications such as switchers, the available kinetic energy and the effectiveness of traction motors as generators are both minimal. For high-speed heavy applications such as freight, the ability of the auxiliary power device to absorb a significant portion of the available kinetic energy is low. Moreover, the hybrid power plant suffers a double efficiency penalty, namely, losses occur in both absorbing and then releasing energy from the auxiliary device, which result in a net storage efficiency of no more than 50% for present battery technology. Capital cost in some applications may be reduced. Based on an observed locomotive duty cycle, a cost model shows that a hybrid power plant for a switcher may indeed reduce capital cost. Offsetting this potential benefit are the increased complexity, weight and volume of the power plant, as well as 20-40% increased fuel consumption that results from lower efficiency. Based on this analysis, the consortium has decided to develop a pure fuel cell road-switcher locomotive

  2. Horizontal plane head stabilization during locomotor tasks.

    Science.gov (United States)

    Cromwell, R L; Newton, R A; Carlton, L G

    2001-03-01

    Frequency characteristics of head stabilization were examined during locomotor tasks in healthy young adults(N = 8) who performed normal walking and 3 walking tasks designed to produce perturbations primarily in the horizontal plane. In the 3 walking tasks, the arms moved in phase with leg movement, with abnormally large amplitude, and at twice the frequency of leg movement. Head-in-space angular velocity was examined at the predominant frequencies of trunk motion. Head movements in space occurred at low frequencies ( 4.0 Hz) when the arms moved at twice the frequency of the legs. Head stabilization strategies were determined from head-on-trunk with respect to trunk frequency profiles derived from angular velocity data. During natural walking at low frequencies (head-on-trunk movement was less than trunk movement. At frequencies 3.0 Hz or greater, equal and opposite compensatory movement ensured head stability. When arm swing was altered, compensatory movement guaranteed head stability at all frequencies. Head stabilization was successful for frequencies up to 10.0 Hz during locomotor tasks. Maintaining head stability at high frequencies during voluntary tasks suggests that participants used feedforward mechanisms to coordinate head and trunk movements. Maintenance of head stability during dynamic tasks allows optimal conditions for vestibulo-ocular reflex function.

  3. Head movements while steering around bends

    NARCIS (Netherlands)

    Erp, J.B.F. van; Oving, A.B.

    2012-01-01

    In this study, the determinants of head motions (rotations) when driving around bends were investigated when drivers viewed the scene through a head-mounted display. The scene camera was either fixed or coupled to head motions along 2 or 3 axes of rotation. Eight participants drove around a

  4. Hybrid electric vehicles TOPTEC

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-06-21

    This one-day TOPTEC session began with an overview of hybrid electric vehicle technology. Updates were given on alternative types of energy storage, APU control for low emissions, simulation programs, and industry and government activities. The keynote speech was about battery technology, a key element to the success of hybrids. The TOPEC concluded with a panel discussion on the mission of hybrid electric vehicles, with a perspective from industry and government experts from United States and Canada on their view of the role of this technology.

  5. Hybrid systems with constraints

    CERN Document Server

    Daafouz, Jamal; Sigalotti, Mario

    2013-01-01

    Control theory is the main subject of this title, in particular analysis and control design for hybrid dynamic systems.The notion of hybrid systems offers a strong theoretical and unified framework to cope with the modeling, analysis and control design of systems where both continuous and discrete dynamics interact. The theory of hybrid systems has been the subject of intensive research over the last decade and a large number of diverse and challenging problems have been investigated. Nevertheless, many important mathematical problems remain open.This book is dedicated mainly to

  6. Hybrid Bloch Brane

    CERN Document Server

    Bazeia, D; Losano, L

    2016-01-01

    This work reports on models described by two real scalar fields coupled with gravity in the five-dimensional spacetime, with a warped geometry involving one infinite extra dimension. Through a mechanism that smoothly changes a thick brane into a hybrid brane, one investigates the appearance of hybrid branes hosting internal structure, characterized by the splitting on the energy density and the volcano potential, induced by the parameter which controls interactions between the two scalar fields. In particular, we investigate distinct symmetric and asymmetric hybrid brane scenarios.

  7. Hybrid Bloch brane

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D.; Lima, Elisama E.M.; Losano, L. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil)

    2017-02-15

    This work reports on models described by two real scalar fields coupled with gravity in the five-dimensional spacetime, with a warped geometry involving one infinite extra dimension. Through a mechanism that smoothly changes a thick brane into a hybrid brane, one investigates the appearance of hybrid branes hosting internal structure, characterized by the splitting on the energy density and the volcano potential, induced by the parameter which controls interactions between the two scalar fields. In particular, we investigate distinct symmetric and asymmetric hybrid brane scenarios. (orig.)

  8. Titanium Alloy Cage Implantation for the Treatment of Ischemic Necrosis of Femoral Head in Dogs

    Institute of Scientific and Technical Information of China (English)

    Ruiying WANG; Yan GAO; Shuhua YANG; Cao YANG

    2008-01-01

    To study the effect of titanium alloy cage on the treatment of the ischemic necrosis of femoral head in dog, the model of the ischemic necrosis of femoral head was made with the liquid nitrogon in 15 hybrid adult dogs. The titanium alloy cage made of a hollow cylinder was driven into the subchondral bone of necrotic femoral head via central channel. The dogs were divided into 3 groups, each group was sacrificed 3, 6, 12 weeks after the operation respectively. No collapse of femoral head was observed after the operation. The position of the cages was good on radiograph. Microscopically, the cancellous bone of necrotic femoral head rebuilt gradually and grew into cage. After 12 weeks of creeping substitution, the cancellous bone filled up the hollow cavity and holes of the cages. It is concluded that the titanium alloy cage can provide structural support for the subchondral bone and prevent collapse and can be used for the treatment of the ischemic necrosis of femoral head.

  9. [Studies on the ploymorphic of sperm of F2 hybrids of red crucian carp x common carp].

    Science.gov (United States)

    Li, Jian Zhong; Liu, Shao Jun; Zhang, Xuan Jie; Feng, Hao; Liu, Yun

    2004-08-01

    AThe ultrastructures of the sperm of F2 hybrids of red crucian carp x common carp were studied by using scanning and transmission electron microscope. The sperm of the F2 hybrids consisted of head, mid-piece and tail. There was no acrosome at the anterior end of the nuclears, whereas there was a vesicle. The results revealed that there existed obviously ploymorphic in the sperm of F2 hybrids. In the water-like semen from males of F2 hybrids, different sizes of the head of the sperm including haploid, diploid, tetraploid, and aneuploid sperm were observed. The head diameter of the smallest sperm was only 1.32 microm, but that of the biggest one was about 18.39 microm, and most of them varied from 1.85 to 2.15 microm. The haploid sperm was normal, while the a-neuploid, diploid, tetraploid and multiploid sperm were abnormal. Among the abnormal sperm, there was a super sperm with about 20 tails, whose head volume was much bigger than that of any other sperm. From the results of the transmission electron microscope, 3 sperm with two nucleus and 1 sperm with two tails were found. This study provided an useful evidence for the mechanism that the formation of tetraploid in F3 hybrids was due to the fertilization of the diploid eggs and diploid sperm produced by F2 hybrids.

  10. Target position relative to the head is essential for predicting head movement during head-free gaze pursuit.

    Science.gov (United States)

    C Pallus, Adam; G Freedman, Edward

    2016-08-01

    Gaze pursuit is the coordinated movement of the eyes and head that allows humans and other foveate animals to track moving objects. The control of smooth pursuit eye movements when the head is restrained is relatively well understood, but how the eyes coordinate with concurrent head movements when the head is free remains unresolved. In this study, we describe behavioral tasks that dissociate head and gaze velocity during head-free pursuit in monkeys. Existing models of gaze pursuit propose that both eye and head movements are driven only by the perceived velocity of the visual target and are therefore unable to account for these data. We show that in addition to target velocity, the positions of the eyes in the orbits and the retinal position of the target are important factors for predicting head movement during pursuit. When the eyes are already near their limits, further pursuit in that direction will be accompanied by more head movement than when the eyes are centered in the orbits, even when target velocity is the same. The step-ramp paradigm, often used in pursuit tasks, produces larger or smaller head movements, depending on the direction of the position step, while gaze pursuit velocity is insensitive to this manipulation. Using these tasks, we can reliably evoke head movements with peak velocities much faster than the target's velocity. Under these circumstances, the compensatory eye movements, which are often called counterproductive since they rotate the eyes in the opposite direction, are essential to maintaining accurate gaze velocity.

  11. Chaotic mixer improves microarray hybridization.

    Science.gov (United States)

    McQuain, Mark K; Seale, Kevin; Peek, Joel; Fisher, Timothy S; Levy, Shawn; Stremler, Mark A; Haselton, Frederick R

    2004-02-15

    Hybridization is an important aspect of microarray experimental design which influences array signal levels and the repeatability of data within an array and across different arrays. Current methods typically require 24h and use target inefficiently. In these studies, we compare hybridization signals obtained in conventional static hybridization, which depends on diffusional target delivery, with signals obtained in a dynamic hybridization chamber, which employs a fluid mixer based on chaotic advection theory to deliver targets across a conventional glass slide array. Microarrays were printed with a pattern of 102 identical probe spots containing a 65-mer oligonucleotide capture probe. Hybridization of a 725-bp fluorescently labeled target was used to measure average target hybridization levels, local signal-to-noise ratios, and array hybridization uniformity. Dynamic hybridization for 1h with 1 or 10ng of target DNA increased hybridization signal intensities approximately threefold over a 24-h static hybridization. Similarly, a 10- or 60-min dynamic hybridization of 10ng of target DNA increased hybridization signal intensities fourfold over a 24h static hybridization. In time course studies, static hybridization reached a maximum within 8 to 12h using either 1 or 10ng of target. In time course studies using the dynamic hybridization chamber, hybridization using 1ng of target increased to a maximum at 4h and that using 10ng of target did not vary over the time points tested. In comparison to static hybridization, dynamic hybridization reduced the signal-to-noise ratios threefold and reduced spot-to-spot variation twofold. Therefore, we conclude that dynamic hybridization based on a chaotic mixer design improves both the speed of hybridization and the maximum level of hybridization while increasing signal-to-noise ratios and reducing spot-to-spot variation.

  12. Supernumerary head of biceps brachii

    OpenAIRE

    Balasubramanian A

    2010-01-01

    The biceps brachii muscle and the musculocutaneous nerve of arm are frequent in their variations. A third head of biceps brachii was noted unilaterally during routine anatomy dissection. Variation in musculocutaneous nerve was also seen on the same arm. The evolutionary and functional basis of such variations are discussed. Such variations become relevant during surgical intervention of the arm, especially after humeral fracture with subsequent unusual bone displacements.

  13. Supernumerary head of biceps brachii

    Directory of Open Access Journals (Sweden)

    Balasubramanian A

    2010-12-01

    Full Text Available The biceps brachii muscle and the musculocutaneous nerve of arm are frequent in their variations. A third head of biceps brachii was noted unilaterally during routine anatomy dissection. Variation in musculocutaneous nerve was also seen on the same arm. The evolutionary and functional basis of such variations are discussed. Such variations become relevant during surgical intervention of the arm, especially after humeral fracture with subsequent unusual bone displacements.

  14. Comparison of gene expression profiles and responses to zinc chloride among inter- and intraspecific hybrids with growth abnormalities in wheat and its relatives.

    Science.gov (United States)

    Takamatsu, Kiyofumi; Iehisa, Julio C M; Nishijima, Ryo; Takumi, Shigeo

    2015-07-01

    Hybrid necrosis is a well-known reproductive isolation mechanism in plant species, and an autoimmune response is generally considered to trigger hybrid necrosis through epistatic interaction between disease resistance-related genes in hybrids. In common wheat, the complementary Ne1 and Ne2 genes control hybrid necrosis, defined as type I necrosis. Two other types of hybrid necrosis (type II and type III) have been observed in interspecific hybrids between tetraploid wheat and Aegilops tauschii. Another type of hybrid necrosis, defined here as type IV necrosis, has been reported in F1 hybrids between Triticum urartu and some accessions of Triticum monococcum ssp. aegilopoides. In types I, III and IV, cell death occurs gradually starting in older tissues, whereas type II necrosis symptoms occur only under low temperature. To compare comprehensive gene expression patterns of hybrids showing growth abnormalities, transcriptome analysis of type I and type IV necrosis was performed using a wheat 38k oligo-DNA microarray. Defense-related genes including many WRKY transcription factor genes were dramatically up-regulated in plants showing type I and type IV necrosis, similarly to other known hybrid abnormalities, suggesting an association with an autoimmune response. Reactive oxygen species generation and necrotic cell death were effectively inhibited by ZnCl2 treatment in types I, III and IV necrosis, suggesting a significant association of Ca(2+) influx in upstream signaling of necrotic cell death in wheat hybrid necrosis.

  15. Hybrid grating reflectors: Origin of ultrabroad stopband

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gyeong Cheol; Taghizadeh, Alireza; Chung, Il-Sug, E-mail: ilch@fotonik.dtu.dk [DTU Fotonik, Department of Photonics Engineering, Technical University of Denmark, DK-2800 Kgs. Lyngby (Denmark)

    2016-04-04

    Hybrid grating (HG) reflectors with a high-refractive-index cap layer added onto a high contrast grating (HCG) provide a high reflectance close to 100% over a broader wavelength range than HCGs. The combination of a cap layer and a grating layer brings a strong Fabry-Perot (FP) resonance as well as a weak guided mode (GM) resonance. Most of the reflected power results from the FP resonance, while the GM resonance plays a key role in achieving a reflectance close to 100% as well as broadening the stopband. An HG sample with 7 InGaAlAs quantum wells included in the cap layer has been fabricated by directly wafer-bonding a III-V cap layer onto a Si grating layer. Its reflection property has been characterized. This heterogeneously integrated HG reflector may allow for a hybrid III-V on Si laser to be thermally efficient, which has promising prospects for silicon photonics light sources and high-speed operation.

  16. Preventing head and neck injury.

    Science.gov (United States)

    McIntosh, A S; McCrory, P

    2005-06-01

    A wide range of head and neck injury risks are present in sport, including catastrophic injury. The literature since 1980 on prevention of head and neck injury in sport was reviewed, focusing on catastrophic and brain injury and identifying the range of injury prevention methods in use. There have been few formal evaluations of injury prevention methods. Approaches that are considered, or have been proven, to be successful in preventing injury include: modification of the baseball; implementation of helmet standards in ice hockey and American football and increased wearing rates; use of full faceguards in ice hockey; changes in rules associated with body contact; implementation of rules to reduce the impact forces in rugby scrums. Helmets and other devices have been shown to reduce the risk of severe head and facial injury, but current designs appear to make little difference to rates of concussion. Research methods involving epidemiological, medical, and human factors are required in combination with biomechanical and technological approaches to reduce further injury risks in sport.

  17. Is Heading in Youth Soccer Dangerous Play?

    Science.gov (United States)

    O'Kane, John W

    2016-01-01

    Soccer is among the most popular youth sports with over 3 million youth players registered in the U.S. Soccer is unique in that players intentionally use their head to strike the ball, leading to concerns that heading could cause acute or chronic brain injury, especially in the immature brains of children. Pub Med search without date restriction was conducted in November 2014 and August 2015 using the terms soccer and concussion, heading and concussion, and youth soccer and concussion. 310 articles were identified and reviewed for applicable content specifically relating to youth athletes, heading, and/or acute or chronic brain injury from soccer. Soccer is a low-risk sport for catastrophic head injury, but concussions are relatively common and heading often plays a role. At all levels of play, concussions are more likely to occur in the act of heading than with other facets of the game. While concussion from heading the ball without other contact to the head appears rare in adult players, some data suggests children are more susceptible to concussion from heading primarily in game situations. Contributing factors include biomechanical forces, less developed technique, and the immature brain's susceptibility to injury. There is no evidence that heading in youth soccer causes any permanent brain injury and there is limited evidence that heading in youth soccer can cause concussion. A reasonable approach based on U.S. Youth Soccer recommendations is to teach heading after age 10 in controlled settings, and heading in games should be delayed until skill acquisition and physical maturity allow the youth player to head correctly with confidence.

  18. Hybrid polymer microspheres

    Science.gov (United States)

    Rembaum, A.

    1980-01-01

    Techniques have been successfully tested for bonding polymeric spheres, typically 0.1 micron in diameter, to spheres with diameter up to 100 microns. Hybrids are being developed as improved packing material for ion-exchange columns, filters, and separators.

  19. Hybrid adsorptive membrane reactor

    Science.gov (United States)

    Tsotsis, Theodore T. (Inventor); Sahimi, Muhammad (Inventor); Fayyaz-Najafi, Babak (Inventor); Harale, Aadesh (Inventor); Park, Byoung-Gi (Inventor); Liu, Paul K. T. (Inventor)

    2011-01-01

    A hybrid adsorbent-membrane reactor in which the chemical reaction, membrane separation, and product adsorption are coupled. Also disclosed are a dual-reactor apparatus and a process using the reactor or the apparatus.

  20. Hybrid photon detectors

    CERN Document Server

    D'Ambrosio, C

    2003-01-01

    Hybrid photon detectors detect light via vacuum photocathodes and accelerate the emitted photoelectrons by an electric field towards inversely polarized silicon anodes, where they are absorbed, thus producing electron-hole pairs. These, in turn, are collected and generate electronic signals on their ohmic contacts. This review first describes the characteristic properties of the main components of hybrid photon detectors: light entrance windows, photocathodes, and silicon anodes. Then, essential relations describing the trajectories of photoelectrons in electric and magnetic fields and their backscattering from the silicon anodes are derived. Depending on their anode configurations, three families of hybrid photon detectors are presented: hybrid photomultiplier tubes with single anodes for photon counting with high sensitivity and for gamma spectroscopy; multi-anode photon detector tubes with anodes subdivided into square or hexagonal pads for position-sensitive photon detection; imaging silicon pixel array t...

  1. Functional hybrid materials

    National Research Council Canada - National Science Library

    Fahmi, Amir; Pietsch, Torsten; Mendoza, Cesar; Cheval, Nicolas

    2009-01-01

    .... This paper describes our group's achievements towards the development of multifunctional nanostructures via self-assembly of hybrid systems based on the block copolymer PS-b-P4VP and inorganic nanoparticles (NPs...

  2. Hybrid Rocket Technology

    Directory of Open Access Journals (Sweden)

    Sankaran Venugopal

    2011-04-01

    Full Text Available With their unique operational characteristics, hybrid rockets can potentially provide safer, lower-cost avenues for spacecraft and missiles than the current solid propellant and liquid propellant systems. Classical hybrids can be throttled for thrust tailoring, perform in-flight motor shutdown and restart. In classical hybrids, the fuel is stored in the form of a solid grain, requiring only half the feed system hardware of liquid bipropellant engines. The commonly used fuels are benign, nontoxic, and not hazardous to store and transport. Solid fuel grains are not highly susceptible to cracks, imperfections, and environmental temperature and are therefore safer to manufacture, store, transport, and use for launch. The status of development based on the experience of the last few decades indicating the maturity of the hybrid rocket technology is given in brief.Defence Science Journal, 2011, 61(3, pp.193-200, DOI:http://dx.doi.org/10.14429/dsj.61.518

  3. Nitrous Paraffin Hybrid Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Nitrous Oxide Paraffin Hybrid engine (N2OP) is a proposed technology designed to provide small launch vehicles with high specific impulse, indefinitely storable...

  4. Hybrid adsorptive membrane reactor

    Science.gov (United States)

    Tsotsis, Theodore T.; Sahimi, Muhammad; Fayyaz-Najafi, Babak; Harale, Aadesh; Park, Byoung-Gi; Liu, Paul K. T.

    2011-03-01

    A hybrid adsorbent-membrane reactor in which the chemical reaction, membrane separation, and product adsorption are coupled. Also disclosed are a dual-reactor apparatus and a process using the reactor or the apparatus.

  5. An Investigation of Craniocervical Posture in Class II & Class III Skeletal Patients

    Directory of Open Access Journals (Sweden)

    T. HoseinZadeh-Nik

    2005-02-01

    Full Text Available Statement of Problem: Craniocervical Posture is a factor in the development and function of Craniofacial Structure. Previous studies of different samples have demonstrated associations between craniocervical posture and craniofacial morphology.Purpose: This study aimed lo examine whether any significant association is evident or not between craniocervical posture and the occurrence of Class il & Class III skeletal malocclusions.Materials and Methods: A sample of 76 subjects with Class II & Class III skeletal malocclusion aged 9-i 1 and>18 years were selected. None of them had received orthodontic treatment. Lateral cephalometric radiographs were taken in natural head position (NHP, and craniocervical and craniohorizental angels were traced and determined for analysis of craniocervical posture. Results: According to the craniocervical posture, most class II skeletal patients have flexed heads and class MI skeletal patients have extended heads, as a result malocclusion in these patients seems to become more severe. With increase in age. class II skeletal patients have more flexed their heads and malocclusion become more severe, while with increase in age in class ill skeletal patients, their heads become extended and once again malocclusion thought lo be more severe. In class II skeletal patients, craniocervical posture has a significant correlation with the vertical growth pattern, but shows little correlation with the horizontal growth pattern. In class 111 skeletal patients, craniocervical posture shows no correlation to any of the vertical & horizontal growth patterns, of course the mean of vertical angles is less in these patients and probably in order to make these relation significant in Class III skeletal patients there is need for more samples, in class II & class III skeletal patients, the amount of Na.prep-point A and pog-Na.prep with craniocervical posture shows a significant correlation. Conclusion: Consideration of craniocervical

  6. First Class Call Stacks: Exploring Head Reduction

    Directory of Open Access Journals (Sweden)

    Philip Johnson-Freyd

    2016-06-01

    Full Text Available Weak-head normalization is inconsistent with functional extensionality in the call-by-name λ-calculus. We explore this problem from a new angle via the conflict between extensionality and effects. Leveraging ideas from work on the λ-calculus with control, we derive and justify alternative operational semantics and a sequence of abstract machines for performing head reduction. Head reduction avoids the problems with weak-head reduction and extensionality, while our operational semantics and associated abstract machines show us how to retain weak-head reduction's ease of implementation.

  7. Hybridity in Disgrace

    Institute of Scientific and Technical Information of China (English)

    刘建平

    2015-01-01

    John Maxwell Coetzee's masterpiece-Disgrace is the representative work about post colonialism.The novel describes a series of disgraceful events happened between the white and the black in the post apartheid South Africa.The famous literature theory-hybridity of Homi K.Bhabha is the very key theory to analyze the work.In post apartheid South Africa,hybridity is the only way for the white and the black to coexist.

  8. Hybrid Baryon Signatures

    CERN Document Server

    Page, P R

    2000-01-01

    We discuss whether a low-lying hybrid baryon should be defined as a three quark - gluon bound state or as three quarks moving on an excited adiabatic potential. We show that the latter definition becomes exact, not only for very heavy quarks, but also for specific dynamics. We review the literature on the signatures of hybrid baryons, with specific reference to strong hadronic decays, electromagnetic couplings, diffractive production and production in psi decay.

  9. Hybrid vertical cavity laser

    DEFF Research Database (Denmark)

    Chung, Il-Sug; Mørk, Jesper

    2010-01-01

    A new hybrid vertical cavity laser structure for silicon photonics is suggested and numerically investigated. It incorporates a silicon subwavelength grating as a mirror and a lateral output coupler to a silicon ridge waveguide.......A new hybrid vertical cavity laser structure for silicon photonics is suggested and numerically investigated. It incorporates a silicon subwavelength grating as a mirror and a lateral output coupler to a silicon ridge waveguide....

  10. Requirements for Hybrid Cosimulation

    Science.gov (United States)

    2014-08-16

    hybrid cosimulation version of the Functional Mockup Interface (FMI) standard. A cosimulation standard de nes interfaces that enable diverse simulation...cosimulation standards, and specifically provides guidance for development of a hybrid cosimulation version of the Functional Mockup Interface (FMI) standard...V. Peetz, and S. Wolf. The functional mockup interface for tool independent exchange of simulation models. In Proc. of the 8-th International

  11. Celestine III and the North

    DEFF Research Database (Denmark)

    Nielsen, Torben Kjersgaard

    2008-01-01

    Artiklen gennemgår pave Cølestin IIIs forhold til de nordiske kongeriger i perioden 1191-1198. Artiklen viser, at paven, som i forskningen traditionelt år har stået i skyggen af sin berømte, energiske og især: yngre efterfølger, Innocens III, har været på forkant med udviklingen i de nordiske rig...

  12. Neuropsychiatric sequelae of head injuries.

    Science.gov (United States)

    McAllister, T W

    1992-06-01

    Based on the above review several general points can be highlighted: Head injuries are extremely common, affecting probably close to 2,000,000 people in this country each year. The most common are nonmissile, closed-head injuries, the majority of which occur in association with motor vehicle accidents. Virtually all studies of head injury suggest a peak incidence in the 15 to 24 years of age group. Coarse measures of outcome suggest that the very young and the elderly have poorer outcomes. Because of improved acute care, however, a large number of young, otherwise healthy patients are surviving head injuries with a variety of profound neuropsychiatric sequelae. Because of the mechanics of brain injury in acceleration-deceleration injuries, certain brain injury profiles are common including orbitofrontal, anterior and inferior temporal contusions, and diffuse axonal injury. The latter particularly affects the corpus callosum, superior cerebellar peduncle, basal ganglia, and periventricular white matter. The neuropsychiatric sequelae follow from the above injury profiles. Cognitive impairment is often diffuse with more prominent deficits in rate of information processing, attention, memory, cognitive flexibility, and problem solving. Prominent impulsivity, affective instability, and disinhibition are seen frequently, secondary to injury to frontal, temporal, and limbic areas. In association with the typical cognitive deficits, these sequelae characterize the frequently noted "personality changes" in TBI patients. In addition, these changes can exacerbate premorbid problems with impulse control. Marked difficulties with substance use, sexual expression, and aggression often result. The constellation of symptoms, which make up the postconcussive syndrome, are seen across the whole spectrum of brain injury severity. Even in so-called mild or minor head injury, these symptoms are likely to have an underlying neuropathologic, neurochemical, or neurophysiologic cause

  13. Detection of HTLV-III RNA in lungs of patients with AIDS and pulmonary involvement

    Energy Technology Data Exchange (ETDEWEB)

    Chayt, K.J.; Harper, M.E.; Marselle, L.M.; Lewin, E.B.; Rose, R.M.; Oleske, J.M.; Epstein, L.G.; Wong-Staal, F.; Gallo, R.C.

    1986-11-07

    A majority of pediatric patients and rare adult patients with the acquired immunodeficiency syndrome (AIDS) develop a chronic respiratory disorder referred to as lymphocytic interstitial pneumonitis (LIP). Efforts to identify an infectious agent responsible for this process so far have failed. In this study, frozen sections of lungs from patients with AIDS and pulmonary disease were tested by in situ molecular hybridization for the presence of cells infected with human T-cell lymphotropic virus type III (HTLV-III) and expressing viral RNA. In the case of an infant with LIP, a relatively high frequency (0.1%) of cells in the lung were found to be positive for HTLV-III RNA. This number is the lower limit of total cells infected since the in situ hybridization technique as applied in this study depends on expression of HTLV-III genes, and previous evidence indicates that a proportion of cells infected with HTLV-III may not express viral RNA. Moreover, this degree of infection of the lung is likely limited to LIP, since in ten patients with AIDS and pulmonary diseases other than LIP, only 0% to 0.002% of cells in lung were positive for viral RNA expression. Thus, HTLV-III may play a direct causal role in the development of LIP in infected patients, implicating its involvement in yet another of the diverse clinical diseases associated with this virus.

  14. Acupuncture in Treating Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer | Division of Cancer Prevention

    Science.gov (United States)

    RATIONALE: Acupuncture may help relieve dry mouth caused by radiation therapy. PURPOSE: This randomized phase III trial is studying to see how well one set of acupuncture points work in comparison to a different set of acupuncture points or standard therapy in treating dry mouth caused by radiation therapy in patients with head and neck cancer. |

  15. Epstein-Barr virus (EBV)-associated lymphoid lesions of the head and neck.

    Science.gov (United States)

    Auerbach, Aaron; Aguilera, Nadine S

    2015-01-01

    Epstein Barr virus (EBV)-related lymphoproliferative processes occur in the head and neck ranging from reactive processes such as infectious mononucleosis to high grade malignant lymphomas. EBV is a ubiquitous herpes virus that infects more than 90% of adults worldwide, and is generally transferred though saliva. Primary infection can occur throughout life. EBV is the first virus linked to malignancies, both epithelial and lymphoid. Both T and B cell lymphomas can be associated with EBV and evidence shows that an individual's response to the acute EBV infection may be critical in the development of subsequent lymphoma. Currently, in situ hybridization for EBER is the most sensitive available test to detect EBV and should be routinely performed in lymphoproliferative lesions of the head and neck. Immunohistochemistry for EBV related proteins, such as LMP1, is much less sensitive than EBER in situ hybridization, but can help determine latency patterns of EBV infection. Although relatively rare, primary EBV-related lymphomas must be considered in the differential of atypical lymphoid proliferations in the head and neck. We present selected EBV-related disorders of the head and neck discussing etiology as well as differential diagnosis.

  16. Tunable functionalization of graphene nanosheets for graphene-organic hybrid photodetectors

    Science.gov (United States)

    Kim, Seong Jun; Song, Wooseok; Kim, Sungho; Kang, Min-A.; Myung, Sung; Lee, Sun Sook; Lim, Jongsun; An, Ki-Seok

    2016-02-01

    Graphene-organic hybrid thin films are promising candidates for use as advanced transparent electrodes and high-performance photodetectors. In this work, we fabricated hybrid thin film structures consisting of graphene and either tetraphenyl-porphyrin (H2TPP) or metalloporphyrins such as aluminum (III) tetraphenyl-porphyrin (Al(III)TPP) and zinc tetraphenyl-porphyrin (ZnTPP). The optical and electrical characteristics of ultrathin photodetectors based on the graphene-organic hybrid layers were subsequently evaluated. A hybrid deposition system capable of both thermal evaporation and vapor phase metalation was employed to synthesize the tunable metalloporphyrin-based thin films. As a proof of concept, we successfully fabricated various graphene-based photodetectors via the simple and efficient vapor-phase metalation of porphyrin. This work may facilitate the development of new architectures for flexible graphene-organic devices.

  17. Expressiveness of multiple heads in CHR

    CERN Document Server

    Di Giusto, Cinzia; Meo, Maria Chiara

    2008-01-01

    Constraint Handling Rules (CHR) are a committed-choice declarative language which has been designed for writing constraint solvers. A CHR program consists of multi-headed guarded rules which allow one to rewrite constraints into simpler ones until a solved form is reached. Many examples in the vast literature on the subject show that multiple heads are important in order to write programs which solve specific problems. On the other hand, the presence of multiples heads complicates considerably the semantics. Therefore, since restricting to single head rules does not affect the Turing completeness of the language, one can legitimately ask whether multiple heads do indeed augment the expressive power of the language. In this paper we answer positively to this question by showing that, under certain reasonable assumptions, it is not possible to encode the CHR language (with multi-headed rules) into a single head language while preserving the intended meaning of programs.

  18. Brief screening indexes for malingering: A confirmation of Vocabulary minus Digit Span from the WAIS-III and the Rarely Missed Index from the WMS-III.

    Science.gov (United States)

    Miller, Lori J; Ryan, Joseph J; Carruthers, Christine A; Cluff, Richard B

    2004-05-01

    This study investigated the specificity of empirically derived screening measures for the detection of symptom exaggeration in persons with a diagnosis of alcohol abuse (n = 30), polysubstance abuse (n = 43), or head trauma (n = 27). The first measure evaluated was Vocabulary (V) minus Digit Span (DS) (Mittenberg, Theroux-Fichera, Zielinski, & Heilbronner, 1995); the second measure was the Rarely Missed Index (RMI) for the WMS-III Logical Memory subtest (Killgore & Della-Pietra, 2000). V-DS misclassified 0% of individuals in the alcohol abuse group, 2% of those in the polysubstance abuse group, and 0% of head injury cases. RMI misclassification rates were 3%, 5%, and 7% for the alcohol abuse, polysubstance abuse, and head injury groups, respectively. Overall accuracy rates were 99% for V-DS and 95% for RMI.

  19. Clinical results after different operative treatment methods of radial head and neck fractures

    DEFF Research Database (Denmark)

    Zwingmann, J; Welzel, M; Dovi-Akue, D

    2013-01-01

    was placed on extracting data describing clinical efficacy and outcome by using the Mason classification and including elbow function scores. A total of 841 clinical studies were identified describing in total the clinical follow-up of 1264 patients. RESULTS: For type II radial head and neck fractures....... If a prosthesis was implanted, the primary implantation seems to be associated with a better outcome after type III (87%) and IV (82%) fractures compared to the results after a secondary implantation. DISCUSSION: Recommendations for surgical treatment of radial head and neck fractures according to the Mason...... the significant best treatment option seems to be ORIF with an overall success rate of 98% by using screws or biodegradable (polylactide) pins. ORIF with a success rate of 92% shows the best results in the treatment of type III fractures and seem to be better than resection and implantation of a prosthesis...

  20. ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Ye Zhuang; Stanley J. Miller; Michelle R. Olderbak; Rich Gebert

    2001-12-01

    A new concept in particulate control, called an advanced hybrid particulate collector (AHPC), is being developed under funding from the U.S. Department of Energy. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in an entirely novel manner. The AHPC concept combines fabric filtration and electrostatic precipitation in the same housing, providing major synergism between the two methods, both in the particulate collection step and in transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and solves the problem of reentrainment and re-collection of dust in conventional baghouses. Phase I of the development effort consisted of design, construction, and testing of a 5.7-m{sup 3}/min (200-acfm) working AHPC model. Results from both 8-hr parametric tests and 100-hr proof-of-concept tests with two different coals demonstrated excellent operability and greater than 99.99% fine-particle collection efficiency. Since all of the developmental goals of Phase I were met, the approach was scaled up in Phase II to a size of 255 m{sup 3}/min (9000 acfm) (equivalent in size to 2.5 MW) and was installed on a slipstream at the Big Stone Power Plant. For Phase II, the AHPC at Big Stone Power Plant was operated continuously from late July 1999 until mid-December 1999. The Phase II results were highly successful in that ultrahigh particle collection efficiency was achieved, pressure drop was well controlled, and system operability was excellent. For Phase III, the AHPC was modified into a more compact configuration, and components were installed that were closer to what would be used in a full-scale commercial design. The modified AHPC was operated from April to July 2000. While operational results were acceptable during this time, inspection of bags in the summer of 2000 revealed some membrane damage to the fabric that appeared to be

  1. Updating quasar bolometric luminosity corrections - III. [O iii] bolometric corrections

    Science.gov (United States)

    Pennell, Alison; Runnoe, Jessie C.; Brotherton, M. S.

    2017-06-01

    We present quasar bolometric corrections using the [O III] λ 5007 narrow emission line luminosity based on the detailed spectral energy distributions of 53 bright quasars at low to moderate redshift (0.0345 diversity, introduces scatter into the L_{[O III]}-Liso relationship. We found that the {[O III]} bolometric correction can be significantly improved by adding a term including the equivalent width ratio R_{Fe II} ≡ EW_{{Fe II}}/EW_{Hβ }, which is an EV1 indicator. Inclusion of R_{Fe II} in predicting Liso is significant at nearly the 3σ level and reduces the scatter and systematic offset of the luminosity residuals. Typically, {[O III]} bolometric corrections are adopted for Type 2 sources where the quasar continuum is not observed and in these cases, R_{Fe II} cannot be measured. We searched for an alternative measure of EV1 that could be measured in the optical spectra of Type 2 sources but were unable to identify one. Thus, the main contribution of this work is to present an improved {[O III]} bolometric correction based on measured bolometric luminosities and highlight the EV1 dependence of the correction in Type 1 sources.

  2. Development of a Hybrid Atomic Force Microscopic Measurement System Combined with White Light Scanning Interferometry

    Directory of Open Access Journals (Sweden)

    Xiaotang Hu

    2011-12-01

    Full Text Available A hybrid atomic force microscopic (AFM measurement system combined with white light scanning interferometry for micro/nanometer dimensional measurement is developed. The system is based on a high precision large-range positioning platform with nanometer accuracy on which a white light scanning interferometric module and an AFM head are built. A compact AFM head is developed using a self-sensing tuning fork probe. The head need no external optical sensors to detect the deflection of the cantilever, which saves room on the head, and it can be directly fixed under an optical microscopic interferometric system. To enhance the system’s dynamic response, the frequency modulation (FM mode is adopted for the AFM head. The measuring data can be traceable through three laser interferometers in the system. The lateral scanning range can reach 25 mm × 25 mm by using a large-range positioning platform. A hybrid method combining AFM and white light scanning interferometry is proposed to improve the AFM measurement efficiency. In this method, the sample is measured firstly by white light scanning interferometry to get an overall coarse morphology, and then, further measured with higher resolution by AFM. Several measuring experiments on standard samples demonstrate the system’s good measurement performance and feasibility of the hybrid measurement method.

  3. Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma.

    Science.gov (United States)

    Persson, Marta; Andrén, Ywonne; Moskaluk, Christopher A; Frierson, Henry F; Cooke, Susanna L; Futreal, Philip Andrew; Kling, Teresia; Nelander, Sven; Nordkvist, Anders; Persson, Fredrik; Stenman, Göran

    2012-08-01

    Adenoid cystic carcinoma (ACC) of the head and neck is a malignant tumor with poor long-term prognosis. Besides the recently identified MYB-NFIB fusion oncogene generated by a t(6;9) translocation, little is known about other genetic alterations in ACC. Using high-resolution, array-based comparative genomic hybridization, and massively paired-end sequencing, we explored genomic alterations in 40 frozen ACCs. Eighty-six percent of the tumors expressed MYB-NFIB fusion transcripts and 97% overexpressed MYB mRNA, indicating that MYB activation is a hallmark of ACC. Thirty-five recurrent copy number alterations (CNAs) were detected, including losses involving 12q, 6q, 9p, 11q, 14q, 1p, and 5q and gains involving 1q, 9p, and 22q. Grade III tumors had on average a significantly higher number of CNAs/tumor compared to Grade I and II tumors (P = 0.007). Losses of 1p, 6q, and 15q were associated with high-grade tumors, whereas losses of 14q were exclusively seen in Grade I tumors. The t(6;9) rearrangements were associated with a complex pattern of breakpoints, deletions, insertions, inversions, and for 9p also gains. Analyses of fusion-negative ACCs using high-resolution arrays and massively paired-end sequencing revealed that MYB may also be deregulated by other mechanisms in addition to gene fusion. Our studies also identified several down-regulated candidate tumor suppressor genes (CTNNBIP1, CASP9, PRDM2, and SFN) in 1p36.33-p35.3 that may be of clinical significance in high-grade tumors. Further, studies of these and other potential target genes may lead to the identification of novel driver genes in ACC.

  4. Management of osteonecrosis of the femoral head: A novel technique

    Directory of Open Access Journals (Sweden)

    Ahmed M Samy

    2016-01-01

    Full Text Available Background: Osteonecrosis of the femoral head (ONFH is a debilitating disease in orthopedics, frequently progressing to femoral head collapse and osteoarthritis. It is thought to be a multifactorial disease. ONFH ultimately results in femoral head collapse in 75-85% of untreated patients. Total hip arthroplasty (THA yields satisfactory results in the treatment of the end stage of the disease. However, disease typically affects males between the ages of 20 and 40 years and joint replacement is not the ideal option for younger patients. Recently, mesenchymal stem cells and platelet rich plasma (PRP have been used as an adjunct to core decompression to improve clinical success in the treatment of precollapse hips. Materials and Methods: A prospective study of 40 hips in 30 patients was done. There were 19 males and 11 females with a mean age 36.7 ± 6.93 years. The indication for the operation was restricted primarily to modified Ficat stages IIb and III. 16 hips (40% had stage IIb and 24 hips (60% had stage III ONFH. The period of follow up ranged between 36-50 months with a mean 41.4 ± 3.53 months. All patients were assessed clinically during pre- and post-operative period according to the Harris Hip Score (HHS, Visual Analog Score (VAS and radiologically by X-rays. Magnetic resonance imaging (MRI was done preoperatively to confirm the diagnosis and every 6 months postoperatively for assessment of healing. The operative procedure include removal of necrotic area with drilling then the cavity was filled with a composite of bone graft mixed with PRP. Results: The mean HHS improved from 46.0 ± 7.8 preoperatively to 90.28 ± 19 at the end of followup ( P < 0.0001. The mean values of VAS were 78 ± 21 and 35 ± 19 at preoperatively period and final followup, respectively, with an average reduction of 43 points. Conclusion: We found that the use of PRP with collagen sheet can increase the reparable capacity after drilling of necrotic segment in stage

  5. Milliped Miscellany — Part III

    NARCIS (Netherlands)

    Jeekel, C.A.W.

    1956-01-01

    MATERIAL: Eritrea: Gula (15° 36’ N., 38° 21’ E.), 500 m., 19 July 1953, Coll. W. J. STOWER, 1 ♂ (holotype). COLOUR : Head, except the lower portion of the clypeus and a sharply demarcated spot at the medio-posterior side of the antennal sockets which are yellowish, very dark brown. Antennae and legs

  6. Head position modulates optokinetic nystagmus

    Science.gov (United States)

    Ferraresi, A.; Botti, F. M.; Panichi, R.; Barmack, N. H.

    2011-01-01

    Orientation and movement relies on both visual and vestibular information mapped in separate coordinate systems. Here, we examine how coordinate systems interact to guide eye movements of rabbits. We exposed rabbits to continuous horizontal optokinetic stimulation (HOKS) at 5°/s to evoke horizontal eye movements, while they were statically or dynamically roll-tilted about the longitudinal axis. During monocular or binocular HOKS, when the rabbit was roll-tilted 30° onto the side of the eye stimulated in the posterior → anterior (P → A) direction, slow phase eye velocity (SPEV) increased by 3.5–5°/s. When the rabbit was roll-tilted 30° onto the side of the eye stimulated in the A → P direction, SPEV decreased to ~2.5°/s. We also tested the effect of roll-tilt after prolonged optokinetic stimulation had induced a negative optokinetic afternystagmus (OKAN II). In this condition, the SPEV occurred in the dark, “open loop.” Modulation of SPEV of OKAN II depended on the direction of the nystagmus and was consistent with that observed during “closed loop” HOKS. Dynamic roll-tilt influenced SPEV evoked by HOKS in a similar way. The amplitude and the phase of SPEV depended on the frequency of vestibular oscillation and on HOKS velocity. We conclude that the change in the linear acceleration of the gravity vector with respect to the head during roll-tilt modulates the gain of SPEV depending on its direction. This modulation improves gaze stability at different image retinal slip velocities caused by head roll-tilt during centric or eccentric head movement. PMID:21735244

  7. A Game Theoretic Optimization Method for Energy Efficient Global Connectivity in Hybrid Wireless Sensor Networks.

    Science.gov (United States)

    Lee, JongHyup; Pak, Dohyun

    2016-08-29

    For practical deployment of wireless sensor networks (WSN), WSNs construct clusters, where a sensor node communicates with other nodes in its cluster, and a cluster head support connectivity between the sensor nodes and a sink node. In hybrid WSNs, cluster heads have cellular network interfaces for global connectivity. However, when WSNs are active and the load of cellular networks is high, the optimal assignment of cluster heads to base stations becomes critical. Therefore, in this paper, we propose a game theoretic model to find the optimal assignment of base stations for hybrid WSNs. Since the communication and energy cost is different according to cellular systems, we devise two game models for TDMA/FDMA and CDMA systems employing power prices to adapt to the varying efficiency of recent wireless technologies. The proposed model is defined on the assumptions of the ideal sensing field, but our evaluation shows that the proposed model is more adaptive and energy efficient than local selections.

  8. A Game Theoretic Optimization Method for Energy Efficient Global Connectivity in Hybrid Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    JongHyup Lee

    2016-08-01

    Full Text Available For practical deployment of wireless sensor networks (WSN, WSNs construct clusters, where a sensor node communicates with other nodes in its cluster, and a cluster head support connectivity between the sensor nodes and a sink node. In hybrid WSNs, cluster heads have cellular network interfaces for global connectivity. However, when WSNs are active and the load of cellular networks is high, the optimal assignment of cluster heads to base stations becomes critical. Therefore, in this paper, we propose a game theoretic model to find the optimal assignment of base stations for hybrid WSNs. Since the communication and energy cost is different according to cellular systems, we devise two game models for TDMA/FDMA and CDMA systems employing power prices to adapt to the varying efficiency of recent wireless technologies. The proposed model is defined on the assumptions of the ideal sensing field, but our evaluation shows that the proposed model is more adaptive and energy efficient than local selections.

  9. Return of the talking heads

    DEFF Research Database (Denmark)

    Reinecke Hansen, Kenneth; Bro, Peter; Andersson, Ralf

    2016-01-01

    . In order to analyze the latest development entering the third wave, we propose a theoretically based dramaturgical model for the television news item. The analysis concludes that, with the current ‘return’ of the talking heads format, the pre-produced and pre-packaged bulletin program about past events...... is dissolving and transforming into an evaluative present- and future-oriented update format that resembles the 24-hour newsonly channels. Production time merges with broadcast time so that the uncertainty of live spreads to the dramaturgy....

  10. Head First jQuery

    CERN Document Server

    Benedetti, Ryan

    2011-01-01

    Want to add more interactivity and polish to your websites? Discover how jQuery can help you build complex scripting functionality in just a few lines of code. With Head First jQuery, you'll quickly get up to speed on this amazing JavaScript library by learning how to navigate HTML documents while handling events, effects, callbacks, and animations. By the time you've completed the book, you'll be incorporating Ajax apps, working seamlessly with HTML and CSS, and handling data with PHP, MySQL and JSON. If you want to learn-and understand-how to create interactive web pages, unobtrusive scrip

  11. Metabolic prediction of important agronomic traits in hybrid rice (Oryza sativa L.).

    Science.gov (United States)

    Dan, Zhiwu; Hu, Jun; Zhou, Wei; Yao, Guoxin; Zhu, Renshan; Zhu, Yingguo; Huang, Wenchao

    2016-02-24

    Hybrid crops have contributed greatly to improvements in global food and fodder production over the past several decades. Nevertheless, the growing population and changing climate have produced food crises and energy shortages. Breeding new elite hybrid varieties is currently an urgent task, but present breeding procedures are time-consuming and labour-intensive. In this study, parental metabolic information was utilized to predict three polygenic traits in hybrid rice. A complete diallel cross population consisting of eighteen rice inbred lines was constructed, and the hybrids' plant height, heading date and grain yield per plant were predicted using 525 metabolites. Metabolic prediction models were built using the partial least square regression method, with predictive abilities ranging from 0.858 to 0.977 for the hybrid phenotypes, relative heterosis, and specific combining ability. Only slight changes in predictive ability were observed between hybrid populations, and nearly no changes were detected between reciprocal hybrids. The outcomes of prediction of the three highly polygenic traits demonstrated that metabolic prediction was an accurate (high predictive abilities) and efficient (unaffected by population genetic structures) strategy for screening promising superior hybrid rice. Exploitation of this pre-hybridization strategy may contribute to rice production improvement and accelerate breeding programs.

  12. Ontogenetic Variation in Biological Activities of Venoms from Hybrids between Bothrops erythromelas and Bothrops neuwiedi Snakes

    Science.gov (United States)

    Santoro, Marcelo Larami; do Carmo, Thaís; Cunha, Bruna Heloísa Lopes; Alves, André Fonseca; Zelanis, André; Serrano, Solange Maria de Toledo; Grego, Kathleen Fernandes; Sant’Anna, Savio Stefanini; Barbaro, Katia Cristina; Fernandes, Wilson

    2015-01-01

    Lance-headed snakes are found in Central and South America, and they account for most snakebites in Brazil. The phylogeny of South American pitvipers has been reviewed, and the presence of natural and non-natural hybrids between different species of Bothrops snakes demonstrates that reproductive isolation of several species is still incomplete. The present study aimed to analyze the biological features, particularly the thrombin-like activity, of venoms from hybrids born in captivity, from the mating of a female Bothrops erythromelas and a male Bothrops neuwiedi, two species whose venoms are known to display ontogenetic variation. Proteolytic activity on azocoll and amidolytic activity on N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (BAPNA) were lowest when hybrids were 3 months old, and increased over body growth, reaching values similar to those of the father when hybrids were 12 months old. The clotting activity on plasma diminished as hybrids grew; venoms from 3- and 6-months old hybrids showed low clotting activity on fibrinogen (i.e., thrombin-like activity), like the mother venom, and such activity was detected only when hybrids were older than 1 year of age. Altogether, these results point out that venom features in hybrid snakes are genetically controlled during the ontogenetic development. Despite the presence of the thrombin-like enzyme gene(s) in hybrid snakes, they are silenced during the first six months of life. PMID:26714190

  13. Ontogenetic Variation in Biological Activities of Venoms from Hybrids between Bothrops erythromelas and Bothrops neuwiedi Snakes.

    Directory of Open Access Journals (Sweden)

    Marcelo Larami Santoro

    Full Text Available Lance-headed snakes are found in Central and South America, and they account for most snakebites in Brazil. The phylogeny of South American pitvipers has been reviewed, and the presence of natural and non-natural hybrids between different species of Bothrops snakes demonstrates that reproductive isolation of several species is still incomplete. The present study aimed to analyze the biological features, particularly the thrombin-like activity, of venoms from hybrids born in captivity, from the mating of a female Bothrops erythromelas and a male Bothrops neuwiedi, two species whose venoms are known to display ontogenetic variation. Proteolytic activity on azocoll and amidolytic activity on N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (BAPNA were lowest when hybrids were 3 months old, and increased over body growth, reaching values similar to those of the father when hybrids were 12 months old. The clotting activity on plasma diminished as hybrids grew; venoms from 3- and 6-months old hybrids showed low clotting activity on fibrinogen (i.e., thrombin-like activity, like the mother venom, and such activity was detected only when hybrids were older than 1 year of age. Altogether, these results point out that venom features in hybrid snakes are genetically controlled during the ontogenetic development. Despite the presence of the thrombin-like enzyme gene(s in hybrid snakes, they are silenced during the first six months of life.

  14. Cervical vertebrae anomalies in patients with class III skeletal malocclusion

    Directory of Open Access Journals (Sweden)

    Shahin Emami Meibodi

    2011-01-01

    Full Text Available Background and Objective : Studies have documented that deviations in skeletal components such as the cranial base, the mid-facial complex and the mandible may be associated with morphological factors in patients with class III skeletal malocclusion. Furthermore, deviations in head and neck posture may be associated with the class III skeletal malocclusion. The purpose of this study was to compare cervical vertebrae morphology in patients with class III skeletal malocclusion and adults with normal occlusion. Materials and Methods: This case-control study assessed 30 patients with class III skeletal malocclusion (aged 17-30 yrs, with normal vertical growth pattern and ANB<0 were compared with 46 controls (aged 17-30 years, with normal vertical growth pattern, ANB=3+1. Cervical vertebrae anomalies (fusion anomalies and posterior arch deficiency were assessed via evaluation of their lateral cephalograms. The t- test and Fisher′s exact test were used for statistical analysis. Results: In the study group, 73.3% had fusion of the body of the cervical vertebrae, while in the control group only 32.6% showed fusion. The fusion in the control group was between C2 and C3 in all cases; whereas, in the study group, fusion was seen between C2-C3, C3-C¬4 or C4-C¬5. Additionally, cervical column deviations occurred significantly more often in the study group compared to the control group (P<0.001. Conclusion : Class III skeletal malocclusion may be associated with fusion of cervical vertebrae and deviation of the cervical column.

  15. Spectrophotometric and pH-Metric Studies of Ce(III, Dy(III, Gd(III,Yb(III and Pr(III Metal Complexes with Rifampicin

    Directory of Open Access Journals (Sweden)

    A. N. Sonar

    2011-01-01

    Full Text Available The metal-ligand and proton-ligand stability constant of Ce(III, Dy(III, Gd(III,Yb(III and Pr(III metals with substituted heterocyclic drug (Rifampicin were determined at various ionic strength by pH metric titration. NaClO4 was used to maintain ionic strength of solution. The results obtained were extrapolated to the zero ionic strength using an equation with one individual parameter. The thermodynamic stability constant of the complexes were also calculated. The formation of complexes has been studied by Job’s method. The results obtained were of stability constants by pH metric method is confirmed by Job’s method.

  16. Head movement during walking in the cat.

    Science.gov (United States)

    Zubair, Humza N; Beloozerova, Irina N; Sun, Hai; Marlinski, Vladimir

    2016-09-22

    Knowledge of how the head moves during locomotion is essential for understanding how locomotion is controlled by sensory systems of the head. We have analyzed head movements of the cat walking along a straight flat pathway in the darkness and light. We found that cats' head left-right translations, and roll and yaw rotations oscillated once per stride, while fore-aft and vertical translations, and pitch rotations oscillated twice. The head reached its highest vertical positions during second half of each forelimb swing, following maxima of the shoulder/trunk by 20-90°. Nose-up rotation followed head upward translation by another 40-90° delay. The peak-to-peak amplitude of vertical translation was ∼1.5cm and amplitude of pitch rotation was ∼3°. Amplitudes of lateral translation and roll rotation were ∼1cm and 1.5-3°, respectively. Overall, cats' heads were neutral in roll and 10-30° nose-down, maintaining horizontal semicircular canals and utriculi within 10° of the earth horizontal. The head longitudinal velocity was 0.5-1m/s, maximal upward and downward linear velocities were ∼0.05 and ∼0.1m/s, respectively, and maximal lateral velocity was ∼0.05m/s. Maximal velocities of head pitch rotation were 20-50°/s. During walking in light, cats stood 0.3-0.5cm taller and held their head 0.5-2cm higher than in darkness. Forward acceleration was 25-100% higher and peak-to-peak amplitude of head pitch oscillations was ∼20°/s larger. We concluded that, during walking, the head of the cat is held actively. Reflexes appear to play only a partial role in determining head movement, and vision might further diminish their role.

  17. Photonic Integration on the Hybrid Silicon Evanescent Device Platform

    Directory of Open Access Journals (Sweden)

    Hyundai Park

    2008-01-01

    Full Text Available This paper reviews the recent progress of hybrid silicon evanescent devices. The hybrid silicon evanescent device structure consists of III-V epitaxial layers transferred to silicon waveguides through a low-temperature wafer bonding process to achieve optical gain, absorption, and modulation efficiently on a silicon photonics platform. The low-temperature wafer bonding process enables fusion of two different material systems without degradation of material quality and is scalable to wafer-level bonding. Lasers, amplifiers, photodetectors, and modulators have been demonstrated with this hybrid structure and integration of these individual components for improved optical functionality is also presented. This approach provides a unique way to build photonic active devices on silicon and should allow application of silicon photonic integrated circuits to optical telecommunication and optical interconnects.

  18. Pediatric abusive head trauma and stroke.

    Science.gov (United States)

    Khan, Nickalus R; Fraser, Brittany D; Nguyen, Vincent; Moore, Kenneth; Boop, Scott; Vaughn, Brandy N; Klimo, Paul

    2017-08-01

    OBJECTIVE Despite established risk factors, abusive head trauma (AHT) continues to plague our communities. Cerebrovascular accident (CVA), depicted as areas of hypodensity on CT scans or diffusion restriction on MR images, is a well-known consequence of AHT, but its etiology remains elusive. The authors hypothesize that a CVA, in isolation or in conjunction with other intracranial injuries, compounds the severity of a child's injury, which in turn leads to greater health care utilization, including surgical services, and an increased risk of death. METHODS The authors conducted a retrospective observational study to evaluate data obtained in all children with AHT who presented to Le Bonheur Children's Hospital (LBCH) from January 2009 through August 2016. Demographic, hospital course, radiological, cost, and readmission information was collected. Children with one or more CVA were compared with those without a CVA. RESULTS The authors identified 282 children with AHT, of whom 79 (28%) had one or more CVA. Compared with individuals without a CVA, children with a stroke were of similar overall age (6 months), sex (61% male), and race (56% African-American) and had similar insurance status (81% public). Just under half of all children with a stroke (38/79, 48%) were between 1-6 months of age. Thirty-five stroke patients (44%) had a Grade II injury, and 44 (56%) had a Grade III injury. The majority of stroke cases were bilateral (78%), multifocal (85%), associated with an overlying subdural hematoma (86%), and were watershed/hypoperfusion in morphology (73%). Thirty-six children (46%) had a hemispheric stroke. There were a total of 48 neurosurgical procedures performed on 28 stroke patients. Overall median hospital length of stay (11 vs 3 days), total hospital charges ($13.8 vs $6.6 million), and mean charges per patient ($174,700 vs $32,500) were significantly higher in the stroke cohort as a whole, as well as by injury grade (II and III). Twenty children in the

  19. The START III bargaining space

    Energy Technology Data Exchange (ETDEWEB)

    Karas, T.H.

    1998-08-01

    The declining state of the Russian military and precarious Russian economic condition will give the US considerable advantages at the START III bargaining table. Taking the US-RF asymmetries into account, this paper discusses a menu of START III measures the US could ask for, and measures it could offer in return, in attempting to negotiate an equitable treaty. Measures the US might seek in a START III treaty include: further reductions in deployed strategic nuclear warheads, irreversibility of reductions through warhead dismantlement; beginning to bring theater nuclear weapons under mutual control, and increased transparency into the Russian nuclear weapons complex. The US may, however, wish to apply its bargaining advantages to attempting to achieve the first steps toward two long-range goals that would enhance US security: bringing theater nuclear weapons into the US-RF arms control arena, and increasing transparency into the Russian nuclear weapons complex. In exchange for measures relating to these objectives, the US might consider offering to Russia: Further strategic weapons reductions approaching levels at which the Russians believe they could maintain a degree of parity with the US; Measures to decrease the large disparities in potential deliver-system uploading capabilities that appear likely under current START II/START III scenarios; and Financial assistance in achieving START II/START III reductions as rapidly as is technically possible.

  20. The Hybrids of Postmodernism

    Directory of Open Access Journals (Sweden)

    Dana BĂDULESCU

    2014-09-01

    Full Text Available Hybridization is a fundamental characteristic of postmodernism, included by Ihab Hassan in his “catena” of features. This paper looks into the hybrids of postmodernism, which are the result of migration, displacement and uprooting, the re-visitation of myths, folklore and legends, or projections of their author’s imagination. The hybrids used as examples here are drawn from several novels written by Salman Rushdie, especially The Satanic Verses, two short stories, one by Márquez and the other by Donald Barthelme, Borges’s Book of Imaginary Beings, Cărtărescu’s Encyclopaedia of Dragons and Michelle Cliff’s No Telephone to Heaven. Diverse as they may be, these hybrids emphasize a defining characteristic of postmodernism, which is its pluralism. I conclude that the hybrids of postmodernism are aesthetically or politically subversive. Besides, what makes them difficult to grasp is their unfixed and protean nature. They ask for high leaps of the imagination, a total suspension of disbelief and a complete surrender to the powerful seduction of imagination on the reader’s part.