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Sample records for hybrid experimental-numerical analysis

  1. A hybrid experimental-numerical technique for determining 3D velocity fields from planar 2D PIV data

    Science.gov (United States)

    Eden, A.; Sigurdson, M.; Mezić, I.; Meinhart, C. D.

    2016-09-01

    Knowledge of 3D, three component velocity fields is central to the understanding and development of effective microfluidic devices for lab-on-chip mixing applications. In this paper we present a hybrid experimental-numerical method for the generation of 3D flow information from 2D particle image velocimetry (PIV) experimental data and finite element simulations of an alternating current electrothermal (ACET) micromixer. A numerical least-squares optimization algorithm is applied to a theory-based 3D multiphysics simulation in conjunction with 2D PIV data to generate an improved estimation of the steady state velocity field. This 3D velocity field can be used to assess mixing phenomena more accurately than would be possible through simulation alone. Our technique can also be used to estimate uncertain quantities in experimental situations by fitting the gathered field data to a simulated physical model. The optimization algorithm reduced the root-mean-squared difference between the experimental and simulated velocity fields in the target region by more than a factor of 4, resulting in an average error less than 12% of the average velocity magnitude.

  2. Local stress analysis on semiconductor devices by combined experimental-numerical procedure

    NARCIS (Netherlands)

    Kregting, R.; Gielen, A.W.J.; Driel, W. van; Alkemade, P.; Miro, H.; Kamminga, J.-D.

    2011-01-01

    Intrinsic stresses in bondpads may lead to early failure of IC's. In order to determine the intrinsic stresses in semiconductor structures, a new procedure is set up. This procedure is a combined experimental/numerical approach which consists of the following steps: First, a conductive gold layer (2

  3. Experimental,numerical and sensitive analysis of nitrogen dynamics in soils irrigated with treated sewage

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    An ammonia volatilization submodel and a crop-growth submodel have been set up and incorporated to the 2D nitrogen transport and transformation simulation model Nitrogen-2D. The coupled model Nitrogen-2D considers all the important nitrogen transformation processes such as mineralization, immobilization, denitrification, nitrification, volatilization, root uptake and soil adsorption in the soil. The model was used to simulate the nitrogen dynamics for the experiment in four lysimeters under sewage irrigation. Simulation results show that the model can describe the water content and ammonium nitrogen content distribution well but simulate the change of the nitrate nitrogen poorly. Sensitivity analysis shows that the simulation results are influenced by the soil water characteristic parameters severely, especially by the parameter of n. The model is much less sensitive to N dynamic parameters.

  4. An experimental-numerical method for comparative analysis of joint prosthesis; Un metodo numerico-experimental para el analisis comparativo de protesis articulares

    Energy Technology Data Exchange (ETDEWEB)

    Claramunt, R.; Rincon, E.; Zubizarreta, V.; Ros, A.

    2001-07-01

    The difficulty that exists in the analysis of mechanical stresses in bones is high due to its complex mechanical and morphological characteristics. This complexity makes generalists modelling and conclusions derived from prototype tests very questionable. In this article a relatively simple comparative analysis systematic method that allow us to establish some behaviour differences in different kind of prosthesis is presented. The method, applicable in principle to any joint problem, is based on analysing perturbations produced in natural stress states of a bone after insertion of a joint prosthesis and combines numerical analysis using a 3-D finite element model and experimental studies based on photoelastic coating and electric extensometry. The experimental method is applied to compare two total hip prosthesis cement-free femoral stems of different philosophy. One anatomic of new generation, being of oblique setting over cancellous bone and the other madreporique of trochantero-diaphyseal support over cortical bone. (Author) 4 refs.

  5. Hybrid methods for cybersecurity analysis :

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Warren Leon,; Dunlavy, Daniel M.

    2014-01-01

    Early 2010 saw a signi cant change in adversarial techniques aimed at network intrusion: a shift from malware delivered via email attachments toward the use of hidden, embedded hyperlinks to initiate sequences of downloads and interactions with web sites and network servers containing malicious software. Enterprise security groups were well poised and experienced in defending the former attacks, but the new types of attacks were larger in number, more challenging to detect, dynamic in nature, and required the development of new technologies and analytic capabilities. The Hybrid LDRD project was aimed at delivering new capabilities in large-scale data modeling and analysis to enterprise security operators and analysts and understanding the challenges of detection and prevention of emerging cybersecurity threats. Leveraging previous LDRD research e orts and capabilities in large-scale relational data analysis, large-scale discrete data analysis and visualization, and streaming data analysis, new modeling and analysis capabilities were quickly brought to bear on the problems in email phishing and spear phishing attacks in the Sandia enterprise security operational groups at the onset of the Hybrid project. As part of this project, a software development and deployment framework was created within the security analyst work ow tool sets to facilitate the delivery and testing of new capabilities as they became available, and machine learning algorithms were developed to address the challenge of dynamic threats. Furthermore, researchers from the Hybrid project were embedded in the security analyst groups for almost a full year, engaged in daily operational activities and routines, creating an atmosphere of trust and collaboration between the researchers and security personnel. The Hybrid project has altered the way that research ideas can be incorporated into the production environments of Sandias enterprise security groups, reducing time to deployment from months and

  6. Symbolic Algorithmic Analysis of Rectangular Hybrid Systems

    Institute of Scientific and Technical Information of China (English)

    Hai-Bin Zhang; Zhen-Hua Duan

    2009-01-01

    This paper investigates symbolic algorithmic analysis of rectangular hybrid systems. To deal with the symbolic reachability problem, a restricted constraint system called hybrid zone is formalized for the representation and manipulation of rectangular automata state-spaces. Hybrid zones are proved to be closed over symbolic reachability operations of rectangular hybrid systems. They are also applied to model-checking procedures for verifying some important classes of timed computation tree logic formulas. To represent hybrid zones, a data structure called difference constraint matrix is defined.These enable us to deal with the symbolic algorithmic analysis of rectangular hybrid systems in an efficient way.

  7. Modeling and analysis using hybrid Petri nets

    CERN Document Server

    Ghomri, Latéfa

    2007-01-01

    This paper is devoted to the use of hybrid Petri nets (PNs) for modeling and control of hybrid dynamic systems (HDS). Modeling, analysis and control of HDS attract ever more of researchers' attention and several works have been devoted to these topics. We consider in this paper the extensions of the PN formalism (initially conceived for modeling and analysis of discrete event systems) in the direction of hybrid modeling. We present, first, the continuous PN models. These models are obtained from discrete PNs by the fluidification of the markings. They constitute the first steps in the extension of PNs toward hybrid modeling. Then, we present two hybrid PN models, which differ in the class of HDS they can deal with. The first one is used for deterministic HDS modeling, whereas the second one can deal with HDS with nondeterministic behavior. Keywords: Hybrid dynamic systems; D-elementary hybrid Petri nets; Hybrid automata; Controller synthesis

  8. Stochastic Reachability Analysis of Hybrid Systems

    CERN Document Server

    Bujorianu, Luminita Manuela

    2012-01-01

    Stochastic reachability analysis (SRA) is a method of analyzing the behavior of control systems which mix discrete and continuous dynamics. For probabilistic discrete systems it has been shown to be a practical verification method but for stochastic hybrid systems it can be rather more. As a verification technique SRA can assess the safety and performance of, for example, autonomous systems, robot and aircraft path planning and multi-agent coordination but it can also be used for the adaptive control of such systems. Stochastic Reachability Analysis of Hybrid Systems is a self-contained and accessible introduction to this novel topic in the analysis and development of stochastic hybrid systems. Beginning with the relevant aspects of Markov models and introducing stochastic hybrid systems, the book then moves on to coverage of reachability analysis for stochastic hybrid systems. Following this build up, the core of the text first formally defines the concept of reachability in the stochastic framework and then...

  9. Experimental, Numerical and Analytical Studies of the MHD-driven plasma jet, instabilities and waves

    Science.gov (United States)

    Zhai, Xiang

    This thesis describes a series of experimental, numerical, and analytical studies involving the Caltech magnetohydrodynamically (MHD)-driven plasma jet experiment. The plasma jet is created via a capacitor discharge that powers a magnetized coaxial planar electrodes system. The jet is collimated and accelerated by the MHD forces. We present three-dimensional ideal MHD finite-volume simulations of the plasma jet experiment using an astrophysical magnetic tower as the baseline model. A compact magnetic energy/helicity injection is exploited in the simulation analogous to both the experiment and to astrophysical situations. Detailed analysis provides a comprehensive description of the interplay of magnetic force, pressure, and flow effects. We delineate both the jet structure and the transition process that converts the injected magnetic energy to other forms. When the experimental jet is sufficiently long, it undergoes a global kink instability and then a secondary local Rayleigh-Taylor instability caused by lateral acceleration of the kink instability. We present an MHD theory of the Rayleigh-Taylor instability on the cylindrical surface of a plasma flux rope in the presence of a lateral external gravity. The Rayleigh-Taylor instability is found to couple to the classic current-driven instability, resulting in a new type of hybrid instability. The coupled instability, produced by combination of helical magnetic field, curvature of the cylindrical geometry, and lateral gravity, is fundamentally different from the classic magnetic Rayleigh-Taylor instability occurring at a two-dimensional planar interface. In the experiment, this instability cascade from macro-scale to micro-scale eventually leads to the failure of MHD. When the Rayleigh-Taylor instability becomes nonlinear, it compresses and pinches the plasma jet to a scale smaller than the ion skin depth and triggers a fast magnetic reconnection. We built a specially designed high-speed 3D magnetic probe and

  10. Analysis and design of hybrid control systems

    Energy Technology Data Exchange (ETDEWEB)

    Malmborg, J.

    1998-05-01

    Different aspects of hybrid control systems are treated: analysis, simulation, design and implementation. A systematic methodology using extended Lyapunov theory for design of hybrid systems is developed. The methodology is based on conventional control designs in separate regions together with a switching strategy. Dynamics are not well defined if the control design methods lead to fast mode switching. The dynamics depend on the salient features of the implementation of the mode switches. A theorem for the stability of second order switching together with the resulting dynamics is derived. The dynamics on an intersection of two sliding sets are defined for two relays working on different time scales. The current simulation packages have problems modeling and simulating hybrid systems. It is shown how fast mode switches can be found before or during simulation. The necessary analysis work is a very small overhead for a modern simulation tool. To get some experience from practical problems with hybrid control the switching strategy is implemented in two different software environments. In one of them a time-optimal controller is added to an existing PID controller on a commercial control system. Successful experiments with this hybrid controller shows the practical use of the method 78 refs, 51 figs, 2 tabs

  11. Bundled Hybrid Offset Riser Global Strength Analysis

    Institute of Scientific and Technical Information of China (English)

    William C.Webster; Zhuang Kang; Wenzhou Liang; Youwei Kang; Liping Sun

    2011-01-01

    Bundled hybrid offset riser(BHOR)global strength analysis,which is more complex than single line offset riser global strength analysis,was carried out in this paper.At first,the equivalent theory is used to deal with BHOR,and then its global strength in manifold cases was analyzed,along with the use of a three-dimensional nonlinear time domain finite element program.So the max bending stress,max circumferential stress,and max axial stress in the BHOR bundle main section(BMS)were obtained,and the values of these three stresses in each riser were obtained through the "stress distribution method".Finally,the Max Von Mises stress in each riser was given and a check was made whether or not they met the demand.This paper provides a reference for strength analysis of the bundled hybrid offset riser and some other bundled pipelines.

  12. Analysis of hybrid viscous damper by real time hybrid simulations

    DEFF Research Database (Denmark)

    Brodersen, Mark Laier; Ou, Ge; Høgsberg, Jan Becker

    2016-01-01

    Results from real time hybrid simulations are compared to full numerical simulations for a hybrid viscous damper, composed of a viscous dashpot in series with an active actuator and a load cell. By controlling the actuator displacement via filtered integral force feedback the damping performance...... of the hybrid viscous damper is improved, while for pure integral force feedback the damper stroke is instead increased. In the real time hybrid simulations viscous damping is emulated by a bang-bang controlled Magneto-Rheological (MR) damper. The controller activates high-frequency modes and generates drift...... in the actuator displacement, and only a fraction of the measured damper force can therefore be used as input to the investigated integral force feedback in the real time hybrid simulations....

  13. Analysis of fuel cell hybrid locomotives

    Science.gov (United States)

    Miller, Arnold R.; Peters, John; Smith, Brian E.; Velev, Omourtag A.

    Led by Vehicle Projects LLC, an international industry-government consortium is developing a 109 t, 1.2 MW road-switcher locomotive for commercial and military railway applications. As part of the feasibility and conceptual-design analysis, a study has been made of the potential benefits of a hybrid power plant in which fuel cells comprise the prime mover and a battery or flywheel provides auxiliary power. The potential benefits of a hybrid power plant are: (i) enhancement of transient power and hence tractive effort; (ii) regenerative braking; (iii) reduction of capital cost. Generally, the tractive effort of a locomotive at low speed is limited by wheel adhesion and not by available power. Enhanced transient power is therefore unlikely to benefit a switcher locomotive, but could assist applications that require high acceleration, e.g. subway trains with all axles powered. In most cases, the value of regeneration in locomotives is minimal. For low-speed applications such as switchers, the available kinetic energy and the effectiveness of traction motors as generators are both minimal. For high-speed heavy applications such as freight, the ability of the auxiliary power device to absorb a significant portion of the available kinetic energy is low. Moreover, the hybrid power plant suffers a double efficiency penalty, namely, losses occur in both absorbing and then releasing energy from the auxiliary device, which result in a net storage efficiency of no more than 50% for present battery technology. Capital cost in some applications may be reduced. Based on an observed locomotive duty cycle, a cost model shows that a hybrid power plant for a switcher may indeed reduce capital cost. Offsetting this potential benefit are the increased complexity, weight and volume of the power plant, as well as 20-40% increased fuel consumption that results from lower efficiency. Based on this analysis, the consortium has decided to develop a pure fuel cell road-switcher locomotive

  14. Analysis of hybrid solar systems

    Science.gov (United States)

    Swisher, J.

    1980-10-01

    The TRNSYS simulation program was used to evaluate the performance of active charge/passive discharge solar systems with water as the working fluid. TRNSYS simulations are used to evaluate the heating performance and cooling augmentation provided by systems in several climates. The results of the simulations are used to develop a simplified analysis tool similar to the F-chart and Phi-bar procedures used for active systems. This tool, currently in a preliminary stage, should provide the designer with quantitative performance estimates for comparison with other passive, active, and nonsolar heating and cooling designs.

  15. Probabilistic Analysis Methods for Hybrid Ventilation

    DEFF Research Database (Denmark)

    Brohus, Henrik; Frier, Christian; Heiselberg, Per

    This paper discusses a general approach for the application of probabilistic analysis methods in the design of ventilation systems. The aims and scope of probabilistic versus deterministic methods are addressed with special emphasis on hybrid ventilation systems. A preliminary application of stoc...... of stochastic differential equations is presented comprising a general heat balance for an arbitrary number of loads and zones in a building to determine the thermal behaviour under random conditions....

  16. Sustainable process design & analysis of hybrid separations

    DEFF Research Database (Denmark)

    Kumar Tula, Anjan; Befort, Bridgette; Garg, Nipun

    2016-01-01

    Distillation is an energy intensive operation in chemical process industries. There are around 40,000 distillation columns in operation in the US, requiring approximately 40% of the total energy consumption in US chemical process industries. However, analysis of separations by distillation has...... shown that more than 50% of energy is spent in purifying the last 5-10% of the distillate product. Membrane modules on the other hand can achieve high purity separations at lower energy costs, but if the flux is high, it requires large membrane area. A hybrid scheme where distillation and membrane...... modules are combined such that each operates at its highest efficiency, has the potential for significant energy reduction without significant increase of capital costs. This paper presents a method for sustainable design of hybrid distillation-membrane schemes with guaranteed reduction of energy...

  17. Sentiment Analysis Using Hybrid Approach: A Survey

    Directory of Open Access Journals (Sweden)

    Chauhan Ashish P

    2015-01-01

    Full Text Available Sentiment analysis is the process of identifying people’s attitude and emotional state’s from language. The main objective is realized by identifying a set of potential features in the review and extracting opinion expressions about those features by exploiting their associations. Opinion mining, also known as Sentiment analysis, plays an important role in this process. It is the study of emotions i.e. Sentiments, Expressionsthat are stated in natural language. Natural language techniques are applied to extract emotions from unstructured data. There are several techniques which can be used to analysis such type of data. Here, we are categorizing these techniques broadly as ”supervised learning”, ”unsupervised learning” and ”hybrid techniques”. The objective of this paper is to provide the overview of Sentiment Analysis, their challenges and a comparative analysis of it’s techniques in the field of Natural Language Processing

  18. Kinematic Analysis of a Hybrid Structure

    Directory of Open Access Journals (Sweden)

    Q.J. Duan

    2012-11-01

    Full Text Available This paper presents a kinematic analysis and simulation of a hybrid structure applied to the new design cable-suspended feed structure (CSFS for the next generation of large spherical radio telescopes. First, considering the requirement that feeds should be tilted from 40° to 60° and that the tracking precision in steady state is 4mm, a novel design of the feed supporting structure including a cable-cabin structure, an AB axis structure and a Stewart platform is performed. Next, kinematic analysis and the simulation of the CSFS are done. Simulations have been developed in combination with the 50m CSFS model, which demonstrate the effectiveness and feasibility of the proposed three-level cable-suspended feed system.

  19. Multivariate analysis applied to tomato hybrid production.

    Science.gov (United States)

    Balasch, S; Nuez, F; Palomares, G; Cuartero, J

    1984-11-01

    Twenty characters were measured on 60 tomato varieties cultivated in the open-air and in polyethylene plastic-house. Data were analyzed by means of principal components, factorial discriminant methods, Mahalanobis D(2) distances and principal coordinate techniques. Factorial discriminant and Mahalanobis D(2) distances methods, both of which require collecting data plant by plant, lead to similar conclusions as the principal components method that only requires taking data by plots. Characters that make up the principal components in both environments studied are the same, although the relative importance of each one of them varies within the principal components. By combining information supplied by multivariate analysis with the inheritance mode of characters, crossings among cultivars can be experimented with that will produce heterotic hybrids showing characters within previously established limits.

  20. Impact of hybrid GSI analysis using ETR ensembles

    Indian Academy of Sciences (India)

    V S Prasad; C J Johny

    2016-04-01

    Performance of a hybrid assimilation system combining 3D Var based NGFS (NCMRWF Global ForecastSystem) with ETR (Ensemble Transform with Rescaling) based Global Ensemble Forecast (GEFS) ofresolution T-190L28 is investigated. The experiment is conducted for a period of one week in June 2013and forecast skills over different spatial domains are compared with respect to mean analysis state.Rainfall forecast is verified over Indian region against combined observations of IMD and NCMRWF.Hybrid assimilation produced marginal improvements in overall forecast skill in comparison with 3DVar. Hybrid experiment made significant improvement in wind forecasts in all the regions on verificationagainst mean analysis. The verification of forecasts with radiosonde observations also show improvementin wind forecasts with the hybrid assimilation. On verification against observations, hybrid experimentshows more improvement in temperature and wind forecasts at upper levels. Both hybrid and operational3D Var failed in prediction of extreme rainfall event over Uttarakhand on 17 June, 2013.

  1. Analysis of Hybrid Hydrogen Systems: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Dean, J.; Braun, R.; Munoz, D.; Penev, M.; Kinchin, C.

    2010-01-01

    Report on biomass pathways for hydrogen production and how they can be hybridized to support renewable electricity generation. Two hybrid systems were studied in detail for process feasibility and economic performance. The best-performing system was estimated to produce hydrogen at costs ($1.67/kg) within Department of Energy targets ($2.10/kg) for central biomass-derived hydrogen production while also providing value-added energy services to the electric grid.

  2. Experimental-numerical study of heat flow in deep low-enthalpy geothermal conditions

    NARCIS (Netherlands)

    Saeid, S.; Al-Khoury, R.; Nick, H.M.; Barends, F.

    2014-01-01

    This paper presents an intensive experimental-numerical study of heat flow in a saturated porous domain. A temperature and a flow rate range compared to that existing in a typical deep low-enthalpy hydrothermal system is studied. Two main issues are examined: the effect of fluid density and viscosit

  3. A Theoretical Analysis of Why Hybrid Ensembles Work

    Directory of Open Access Journals (Sweden)

    Kuo-Wei Hsu

    2017-01-01

    Full Text Available Inspired by the group decision making process, ensembles or combinations of classifiers have been found favorable in a wide variety of application domains. Some researchers propose to use the mixture of two different types of classification algorithms to create a hybrid ensemble. Why does such an ensemble work? The question remains. Following the concept of diversity, which is one of the fundamental elements of the success of ensembles, we conduct a theoretical analysis of why hybrid ensembles work, connecting using different algorithms to accuracy gain. We also conduct experiments on classification performance of hybrid ensembles of classifiers created by decision tree and naïve Bayes classification algorithms, each of which is a top data mining algorithm and often used to create non-hybrid ensembles. Therefore, through this paper, we provide a complement to the theoretical foundation of creating and using hybrid ensembles.

  4. Mars Hybrid Propulsion System Trajectory Analysis. Part II; Cargo Missions

    Science.gov (United States)

    Chai, Patrick R.; Merrill, Raymond G.; Qu, Min

    2015-01-01

    NASA's Human Spaceflight Architecture Team is developing a reusable hybrid transportation architecture in which both chemical and electric propulsion systems are used to send crew and cargo to Mars destinations such as Phobos, Deimos, the surface of Mars, and other orbits around Mars. By combining chemical and electrical propulsion into a single spaceship and applying each where it is more effective, the hybrid architecture enables a series of Mars trajectories that are more fuel-efficient than an all chemical architecture without significant increases in flight times. This paper shows the feasibility of the hybrid transportation architecture to pre-deploy cargo to Mars and Phobos in support of the Evolvable Mars Campaign crew missions. The analysis shows that the hybrid propulsion stage is able to deliver all of the current manifested payload to Phobos and Mars through the first three crew missions. The conjunction class trajectory also allows the hybrid propulsion stage to return to Earth in a timely fashion so it can be reused for additional cargo deployment. The 1,100 days total trip time allows the hybrid propulsion stage to deliver cargo to Mars every other Earth-Mars transit opportunity. For the first two Mars surface mission in the Evolvable Mars Campaign, the short trip time allows the hybrid propulsion stage to be reused for three round-trip journeys to Mars, which matches the hybrid propulsion stage's designed lifetime for three round-trip crew missions to the Martian sphere of influence.

  5. New techniques for emulsion analysis in a hybrid experiment

    Energy Technology Data Exchange (ETDEWEB)

    Kodama, K. (Aichi University of Education, Kariya 448 (Japan)); Ushida, N. (Aichi University of Education, Kariya 448 (Japan)); Mokhtarani, A. (University of California (Davis), Davis, CA 95616 (United States)); Paolone, V.S. (University of California (Davis), Davis, CA 95616 (United States)); Volk, J.T. (University of California (Davis), Davis, CA 95616 (United States)); Wilcox, J.O. (University of California (Davis), Davis, CA 95616 (United States)); Yager, P.M. (University of California (Davis), Davis, CA 95616 (United States)); Edelstein, R.M. (Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)); Freyberger, A.P. (Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)); Gibaut, D.B. (Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)); Lipton, R.J. (Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)); Nichols, W.R. (Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)); Potter, D.M. (Carnegie-Mellon Univers

    1994-08-01

    A new method, called graphic scanning, was developed by the Nagoya University Group for emulsion analysis in a hybrid experiment. This method enhances both speed and reliability of emulsion analysis. Details of the application of this technique to the analysis of Fermilab experiment E653 are described. ((orig.))

  6. Analysis of nuclear and organellar DNA in somatic hybrids between solanaceous species.

    NARCIS (Netherlands)

    Wolters, A.M.A.

    1994-01-01

    This thesis describes an analysis of the possibilities and limitations of somatic hybridization of solanaceous species. Emphasis was laid on the elucidation of the interactions between nuclei, chloroplasts and mitochondria in the obtained somatic hybrids. Hybridization experiments between tomato ( L

  7. Hybrid Dynamic Network Data Envelopment Analysis

    Directory of Open Access Journals (Sweden)

    Ling Li

    2015-01-01

    Full Text Available Conventional DEA models make no hypothesis concerning the internal operations in a static situation. To open the “black box” and work with dynamic assessment issues synchronously, we put forward a hybrid model for evaluating the relative efficiencies of a set of DMUs over an observed time period with a composite of network DEA and dynamic DEA. We vertically deal with intermediate products between divisions with assignable inputs in the network structure and, horizontally, we extend network structure by means of a dynamic pattern with unrelated activities between two succeeding periods. The hybrid dynamic network DEA model proposed in this paper enables us to (i pry into the internal operations of DEA by another network structure, (ii obtain dynamic change of period efficiency, and (iii gain the overall dynamic efficiency of DMUs over the entire observed periods. We finally illustrate the calculation procedure of the proposed approach by a numerical example.

  8. Analysis of Synchronization for Coupled Hybrid Systems

    DEFF Research Database (Denmark)

    Li, Zheng; Wisniewski, Rafal

    2006-01-01

    In the control systems with coupled multi-subsystem, the subsystems might be synchronized (i.e. all the subsystems have the same operation states), which results in negative influence to the whole system. For example, in the supermarket refrigeration systems, the synchronized switch of each...... subsystem will cause low efficiency, inferior control performance and a high wear on the compressor. This paper takes the supermarket refrigeration systems as an example to analyze the synchronization and its coupling strengths of coupled hybrid systems, which may provide a base for further research...

  9. Hybrid energy system cost analysis: San Nicolas Island, California

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, T.L.; McKenna, E.

    1996-07-01

    This report analyzes the local wind resource and evaluates the costs and benefits of supplementing the current diesel-powered energy system on San Nicolas Island, California (SNI), with wind turbines. In Section 2.0 the SNI site, naval operations, and current energy system are described, as are the data collection and analysis procedures. Section 3.0 summarizes the wind resource data and analyses that were presented in NREL/TP 442-20231. Sections 4.0 and 5.0 present the conceptual design and cost analysis of a hybrid wind and diesel energy system on SNI, with conclusions following in Section 6. Appendix A presents summary pages of the hybrid system spreadsheet model, and Appendix B contains input and output files for the HYBRID2 program.

  10. Hybrid Ventilation with Innovative Heat Recovery—A System Analysis

    Directory of Open Access Journals (Sweden)

    Bengt Hellström

    2013-02-01

    Full Text Available One of the most important factors when low energy houses are built is to have good heat recovery on the ventilation system. However, standard ventilation units use a considerable amount of electricity. This article discusses the consequences on a system level of using hybrid ventilation with heat recovery. The simulation program TRNSYS was used in order to investigate a ventilation system with heat recovery. The system also includes a ground source storage and waste water heat recovery system. The result of the analysis shows that the annual energy gain from ground source storage is limited. However, this is partly a consequence of the fact that the well functioning hybrid ventilation system leaves little room for improvements. The analysis shows that the hybrid ventilation system has potential to be an attractive solution for low energy buildings with a very low need for electrical energy.

  11. Buckling analysis of a ring stiffened hybrid composite cylinder

    Science.gov (United States)

    Potluri, Rakesh; Eswara Kumar, A.; Navuri, Karteek; Nagaraju, M.; Mojeswara Rao, Duduku

    2016-09-01

    This study aims to understand the response of the ring stiffened cylinders made up of hybrid composites subjected to buckling loads by using the concepts of Design of Experiments (DOE) and optimization by using Finite Element Method (FEM) simulation software Ansys workbench V15. Carbon epoxy and E-glass epoxy composites were used in the hybrid composite. This hybrid composite was analyzed by using different layup angles. Central composite design (CCD) was used to perform design of experiments (D.O.E) and kriging method was used to generate a response surface. The response surface optimization (RSO) was performed by using the method of the multi-objective genetic algorithm (MOGA). After optimization, the best candidate was chosen and applied to the ring stiffened cylinder and eigenvalue buckling analysis was performed to understand the buckling behavior. Best laminate candidates with high buckling strength have been identified. A generalized procedure of the laminate optimization and analysis have been shown.

  12. Mars Hybrid Propulsion System Trajectory Analysis. Part I; Crew Missions

    Science.gov (United States)

    Chai, Patrick R.; Merrill, Raymond G.; Qu, Min

    2015-01-01

    NASAs Human spaceflight Architecture team is developing a reusable hybrid transportation architecture in which both chemical and electric propulsion systems are used to send crew and cargo to Mars destinations such as Phobos, Deimos, the surface of Mars, and other orbits around Mars. By combining chemical and electrical propulsion into a single space- ship and applying each where it is more effective, the hybrid architecture enables a series of Mars trajectories that are more fuel-efficient than an all chemical architecture without significant increases in flight times. This paper provides the analysis of the interplanetary segments of the three Evolvable Mars Campaign crew missions to Mars using the hybrid transportation architecture. The trajectory analysis provides departure and arrival dates and propellant needs for the three crew missions that are used by the campaign analysis team for campaign build-up and logistics aggregation analysis. Sensitivity analyses were performed to investigate the impact of mass growth, departure window, and propulsion system performance on the hybrid transportation architecture. The results and system analysis from this paper contribute to analyses of the other human spaceflight architecture team tasks and feed into the definition of the Evolvable Mars Campaign.

  13. Modelling and analysis of real-time and hybrid systems

    Energy Technology Data Exchange (ETDEWEB)

    Olivero, A.

    1994-09-29

    This work deals with the modelling and analysis of real-time and hybrid systems. We first present the timed-graphs as model for the real-time systems and we recall the basic notions of the analysis of real-time systems. We describe the temporal properties on the timed-graphs using TCTL formulas. We consider two methods for property verification: in one hand we study the symbolic model-checking (based on backward analysis) and in the other hand we propose a verification method derived of the construction of the simulation graph (based on forward analysis). Both methods have been implemented within the KRONOS verification tool. Their application for the automatic verification on several real-time systems confirms the practical interest of our approach. In a second part we study the hybrid systems, systems combining discrete components with continuous ones. As in the general case the analysis of this king of systems is not decidable, we identify two sub-classes of hybrid systems and we give a construction based method for the generation of a timed-graph from an element into the sub-classes. We prove that in one case the timed-graph obtained is bi-similar with the considered system and that there exists a simulation in the other case. These relationships allow the application of the described technics on the hybrid systems into the defined sub-classes. (authors). 60 refs., 43 figs., 8 tabs., 2 annexes.

  14. Hybrid reliability model for fatigue reliability analysis of steel bridges

    Institute of Scientific and Technical Information of China (English)

    曹珊珊; 雷俊卿

    2016-01-01

    A kind of hybrid reliability model is presented to solve the fatigue reliability problems of steel bridges. The cumulative damage model is one kind of the models used in fatigue reliability analysis. The parameter characteristics of the model can be described as probabilistic and interval. The two-stage hybrid reliability model is given with a theoretical foundation and a solving algorithm to solve the hybrid reliability problems. The theoretical foundation is established by the consistency relationships of interval reliability model and probability reliability model with normally distributed variables in theory. The solving process is combined with the definition of interval reliability index and the probabilistic algorithm. With the consideration of the parameter characteristics of theS−N curve, the cumulative damage model with hybrid variables is given based on the standards from different countries. Lastly, a case of steel structure in the Neville Island Bridge is analyzed to verify the applicability of the hybrid reliability model in fatigue reliability analysis based on the AASHTO.

  15. The hebridological analysis of productivity traits in pea hybrids

    Directory of Open Access Journals (Sweden)

    Світлана Володимирівна Коблай

    2015-09-01

    Full Text Available To study the nature of inheritance of quantitative traits that influence productivity of pea hybrids were obtained first and second generations for which sample and varieties with different leaf morphotype are served as parental form. As the results of hybridological analysis it is determined the degree of domination and revealed the heterosis combinations

  16. Nuclear-Renewable Hybrid Energy System Market Analysis Plans

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, Mark

    2016-06-09

    This presentation describes nuclear-renewable hybrid energy systems (N-R HESs), states their potential benefits, provides figures for the four tightly coupled N-R HESs that NREL is currently analyzing, and outlines the analysis process that is underway.

  17. Validation of a hybrid life-cycle inventory analysis method.

    Science.gov (United States)

    Crawford, Robert H

    2008-08-01

    The life-cycle inventory analysis step of a life-cycle assessment (LCA) may currently suffer from several limitations, mainly concerned with the use of incomplete and unreliable data sources and methods of assessment. Many past LCA studies have used traditional inventory analysis methods, namely process analysis and input-output analysis. More recently, hybrid inventory analysis methods have been developed, combining these two traditional methods in an attempt to minimise their limitations. In light of recent improvements, these hybrid methods need to be compared and validated, as these too have been considered to have several limitations. This paper evaluates a recently developed hybrid inventory analysis method which aims to improve the limitations of previous methods. It was found that the truncation associated with process analysis can be up to 87%, reflecting the considerable shortcomings in the quantity of process data currently available. Capital inputs were found to account for up to 22% of the total inputs to a particular product. These findings suggest that current best-practice methods are sufficiently accurate for most typical applications, but this is heavily dependent upon data quality and availability. The use of input-output data assists in improving the system boundary completeness of life-cycle inventories. However, the use of input-output analysis alone does not always provide an accurate model for replacing process data. Further improvements in the quantity of process data currently available are needed to increase the reliability of life-cycle inventories.

  18. Cytogenetic analysis from DNA by comparative genomic hybridization.

    Science.gov (United States)

    Tachdjian, G; Aboura, A; Lapierre, J M; Viguié, F

    2000-01-01

    Comparative genomic hybridization (CGH) is a modified in situ hybridization technique which allows detection and mapping of DNA sequence copy differences between two genomes in a single experiment. In CGH analysis, two differentially labelled genomic DNA (study and reference) are co-hybridized to normal metaphase spreads. Chromosomal locations of copy number changes in the DNA segments of the study genome are revealed by a variable fluorescence intensity ratio along each target chromosome. Since its development, CGH has been applied mostly as a research tool in the field of cancer cytogenetics to identify genetic changes in many previously unknown regions. CGH may also have a role in clinical cytogenetics for detection and identification of unbalanced chromosomal abnormalities.

  19. Hybrid vehicle assessment. Phase 1: Petroleum savings analysis

    Science.gov (United States)

    Levin, R.; Liddle, S.; Deshpande, G.; Trummel, M.; Vivian, H. C.

    1984-01-01

    The results of a comprehensive analysis of near term electric hybrid vehicles are presented, with emphasis on their potential to save significant amounts of petroleum on a national scale in the 1990s. Performance requirements and expected annual usage patterns of these vehicles are first modeled. The projected U.S. fleet composition is estimated, and conceptual hybrid vehicle designs are conceived and analyzed for petroleum use when driven in the expected annual patterns. These petroleum consumption estimates are then compared to similar estimates for projected 1990 conventional vehicles having the same performance and driven in the same patterns. Results are presented in the form of three utility functions and comparisons of sevral conceptual designs are made. The Hybrid Vehicle (HV) design and assessment techniques are discussed and a general method is explained for selecting the optimum energy management strategy for any vehicle mission battery combination. Conclusions and recommendations are presented, and development recommendations are identified.

  20. Proteomic Analysis of Pachytene Spermatocytes of Sterile Hybrid Male Mice.

    Science.gov (United States)

    Wang, Lu; Guo, Yueshuai; Liu, Wenjing; Zhao, Weidong; Song, Gendi; Zhou, Tao; Huang, Hefeng; Guo, Xuejiang; Sun, Fei

    2016-09-01

    Incompatibilities in interspecific hybrids, such as reduced hybrid fertility and lethality, are common features resulting from reproductive isolation that lead to speciation. Subspecies crosses of house mice produce offspring in which one sex is infertile or absent, yet the molecular mechanisms of hybrid sterility are poorly understood. In this study, we observed extensive asynapsis of chromosomes and disturbance of the sex body in pachytene spermatocytes of sterile F1 males (PWK/Ph female × C57BL/6J male). We report the high-confidence identification of 4005 proteins in the pachytene spermatocytes of fertile F1 males (PWK/Ph male × C57BL/6J female) and sterile F1 males (PWK/Ph female × C57BL/6J male), of which 215 were upregulated and 381 were downregulated. Bioinformatics analysis of the proteome led to the identification of 43 and 59 proteins known to be essential for male meiosis and spermatogenesis in mice, respectively. Characterization of the proteome of pachytene spermatocytes associated with hybrid male sterility provides an inventory of proteins that is useful for understanding meiosis and the mechanisms of hybrid male infertility.

  1. Intelligent Hybrid Cluster Based Classification Algorithm for Social Network Analysis

    Directory of Open Access Journals (Sweden)

    S. Muthurajkumar

    2014-05-01

    Full Text Available In this paper, we propose an hybrid clustering based classification algorithm based on mean approach to effectively classify to mine the ordered sequences (paths from weblog data in order to perform social network analysis. In the system proposed in this work for social pattern analysis, the sequences of human activities are typically analyzed by switching behaviors, which are likely to produce overlapping clusters. In this proposed system, a robust Modified Boosting algorithm is proposed to hybrid clustering based classification for clustering the data. This work is useful to provide connection between the aggregated features from the network data and traditional indices used in social network analysis. Experimental results show that the proposed algorithm improves the decision results from data clustering when combined with the proposed classification algorithm and hence it is proved that of provides better classification accuracy when tested with Weblog dataset. In addition, this algorithm improves the predictive performance especially for multiclass datasets which can increases the accuracy.

  2. Hybrid Expert Systems In Image Analysis

    Science.gov (United States)

    Dixon, Mark J.; Gregory, Paul J.

    1987-04-01

    Vision systems capable of inspecting industrial components and assemblies have a large potential market if they can be easily programmed and produced quickly. Currently, vision application software written in conventional high-level languages such as C or Pascal are produced by experts in program design, image analysis, and process control. Applications written this way are difficult to maintain and modify. Unless other similar inspection problems can be found, the final program is essentially one-off redundant code. A general-purpose vision system targeted for the Visual Machines Ltd. C-VAS 3000 image processing workstation, is described which will make writing image analysis software accessible to the non-expert both in programming computers and image analysis. A significant reduction in the effort required to produce vision systems, will be gained through a graphically-driven interactive application generator. Finally, an Expert System will be layered on top to guide the naive user through the process of generating an application.

  3. DNA hybridization sensing for cytogenetic analysis

    DEFF Research Database (Denmark)

    Kwasny, Dorota; Dapra, Johannes; Brøgger, Anna Line;

    2013-01-01

    Cytogenetic analysis focuses on studying the cell structure, mainly in respect to chromosome content and their structure. Chromosome abnormalities, such as translocations may cause various genetic disorders, but are also associated with heametological malignancies. Chromosome translocations...... for cheaper detection a label-free approach has been investigated using electrochemical impedance spectroscopy as a sensing method. We present here our recent results in regards to DNA sensing on metallic and conductive polymer electrodes for translocation detection. Our sensors are inexpensive and can...... be successfully applied in cytogenetic analysis as a replacement of standard techniques....

  4. Analysis of Linear Hybrid Systems in CLP

    DEFF Research Database (Denmark)

    Banda, Gourinath; Gallagher, John Patrick

    2009-01-01

    notation for specifying real-time systems. The main contributions are (i) a technique for capturing the reachable states of the continuously changing state variables of the LHA as CLP constraints; (ii) a way of representing events in the LHA as constraints in CLP, along with a product construction...... and argue that we contribute to the general field of using static analysis tools for verification...

  5. Fuel cell hybrid taxi life cycle analysis

    Energy Technology Data Exchange (ETDEWEB)

    Baptista, Patricia, E-mail: patricia.baptista@ist.utl.pt [IDMEC-Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1, 1049-001 Lisboa (Portugal); Ribau, Joao; Bravo, Joao; Silva, Carla [IDMEC-Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1, 1049-001 Lisboa (Portugal); Adcock, Paul; Kells, Ashley [Intelligent Energy, Charnwood Building, HolywellPark, Ashby Road, Loughborough, LE11 3GR (United Kingdom)

    2011-09-15

    A small fleet of classic London Taxis (Black cabs) equipped with hydrogen fuel cell power systems is being prepared for demonstration during the 2012 London Olympics. This paper presents a Life Cycle Analysis for these vehicles in terms of energy consumption and CO{sub 2} emissions, focusing on the impacts of alternative vehicle technologies for the Taxi, combining the fuel life cycle (Tank-to-Wheel and Well-to-Tank) and vehicle materials Cradle-to-Grave. An internal combustion engine diesel taxi was used as the reference vehicle for the currently available technology. This is compared to battery and fuel cell vehicle configurations. Accordingly, the following energy pathways are compared: diesel, electricity and hydrogen (derived from natural gas steam reforming). Full Life Cycle Analysis, using the PCO-CENEX drive cycle, (derived from actual London Taxi drive cycles) shows that the fuel cell powered vehicle configurations have lower energy consumption (4.34 MJ/km) and CO{sub 2} emissions (235 g/km) than both the ICE Diesel (9.54 MJ/km and 738 g/km) and the battery electric vehicle (5.81 MJ/km and 269 g/km). - Highlights: > A Life Cycle Analysis of alternative vehicle technologies for the London Taxi was performed. > The hydrogen powered vehicles have the lowest energy consumption and CO{sub 2} emissions results. > A hydrogen powered solution can be a sustainable alternative in a full life cycle framework.

  6. Hybrid vehicle assessment. Phase I. Petroleum savings analysis

    Energy Technology Data Exchange (ETDEWEB)

    Levin, R.; Liddle, S.; Deshpande, G.; Trummel, M.; Vivian, H.

    1984-03-01

    This report presents the results of a comprehensive analysis of near-term electric-hybrid vehicles. Its purpose was to estimate their potential to save significant amounts of petroleum on a national scale in the 1990s. Performance requirements and expected annual usage patterns of these vehicles were first modeled. The projected US fleet composition was estimated, and conceptual hybrid vehicle designs were conceived and analyzed for petroleum use when driven in the expected annual patterns. These petroleum consumption estimates were then compared to similar estimates for projected 1990 conventional vehicles having the same performance and driven in the same patterns. Results are presented in the form of three utility functions and comparisons of several conceptual designs are made. The Hybrid Vehicle (HV) design and assessment techniques are discussed and a general method is explained for selecting the optimum energy management strategy for any vehicle-mission-battery combination. A discussion of lessons learned during the construction and test of the General Electric Hybrid Test Vehicle is also presented. Conclusions and recommendations are presented, and development recommendations are identified.

  7. Performance Analysis of a Hybrid Power Cutting System for Roadheader

    Directory of Open Access Journals (Sweden)

    Yang Yang

    2017-01-01

    Full Text Available An electrohydraulic hybrid power cutting transmission system for roadheader under specific working condition was proposed in this paper. The overall model for the new system composed of an electric motor model, a hydraulic pump-motor model, a torsional planetary set model, and a hybrid power train model was established. The working mode characteristics were simulated under the conditions of taking the effect of cutting picks into account. The advantages of new hybrid power cutting system about the dynamic response under shock load were investigated compared with the traditional cutting system. The results illustrated that the hybrid power system had an obvious cushioning in terms of the dynamic load of cutting electric motor and planetary gear set. Besides, the hydraulic motor could provide an auxiliary power to improve the performance of the electric motor. With further analysis, a dynamic load was found to have a high relation to the stiffness and damping of coupling in the transmission train. The results could be a useful guide for the design of cutting transmission of roadheader.

  8. Dance in mental health nursing: a hybrid concept analysis.

    Science.gov (United States)

    Ravelin, Teija; Kylmä, Jari; Korhonen, Teija

    2006-04-01

    The aim of this concept analysis is to describe the defining attributes and consequences of the concept of dance and to define it in a mental health nursing context using hybrid concept analysis. Dance is a human resource learned from culture. Dance implies body movements, steps, expression, and interaction. The outcomes of dance are mostly functional, including a client's physical and emotional health, well-being, ability to cooperate with other people in activities of daily life, and meeting role expectations within family and community. Based on the findings of this concept analysis, dance can be used as a nursing intervention.

  9. A hybrid monkey search algorithm for clustering analysis.

    Science.gov (United States)

    Chen, Xin; Zhou, Yongquan; Luo, Qifang

    2014-01-01

    Clustering is a popular data analysis and data mining technique. The k-means clustering algorithm is one of the most commonly used methods. However, it highly depends on the initial solution and is easy to fall into local optimum solution. In view of the disadvantages of the k-means method, this paper proposed a hybrid monkey algorithm based on search operator of artificial bee colony algorithm for clustering analysis and experiment on synthetic and real life datasets to show that the algorithm has a good performance than that of the basic monkey algorithm for clustering analysis.

  10. A Hybrid Monkey Search Algorithm for Clustering Analysis

    Directory of Open Access Journals (Sweden)

    Xin Chen

    2014-01-01

    Full Text Available Clustering is a popular data analysis and data mining technique. The k-means clustering algorithm is one of the most commonly used methods. However, it highly depends on the initial solution and is easy to fall into local optimum solution. In view of the disadvantages of the k-means method, this paper proposed a hybrid monkey algorithm based on search operator of artificial bee colony algorithm for clustering analysis and experiment on synthetic and real life datasets to show that the algorithm has a good performance than that of the basic monkey algorithm for clustering analysis.

  11. A hybrid transfinite element approach for nonlinear transient thermal analysis

    Science.gov (United States)

    Tamma, Kumar K.; Railkar, Sudhir B.

    1987-01-01

    A new computational approach for transient nonlinear thermal analysis of structures is proposed. It is a hybrid approach which combines the modeling versatility of contemporary finite elements in conjunction with transform methods and classical Bubnov-Galerkin schemes. The present study is limited to nonlinearities due to temperature-dependent thermophysical properties. Numerical test cases attest to the basic capabilities and therein validate the transfinite element approach by means of comparisons with conventional finite element schemes and/or available solutions.

  12. Performance analysis of a hybrid fingerprint extracted from optical coherence tomography fingertip scans

    CSIR Research Space (South Africa)

    Darlow, Luke N

    2016-06-01

    Full Text Available International Conference on Biometrics (ICB), 13-16 June 2016, Halmstad, Sweden Performance analysis of a hybrid fingerprint extracted from optical coherence tomography fingertip scans Darlow LN Connan J Singh A ABSTRACT: The Hybrid fingerprint is a...

  13. Analysis/design of strip reinforced random composites (strip hybrids)

    Science.gov (United States)

    Chamis, C. C.; Sinclair, J. H.

    1978-01-01

    Advanced analysis methods and composite mechanics were applied to a strip-reinforced random composite square panel with fixed ends to illustrate the use of these methods for the a priori assessment of the composite panel when subjected to complex loading conditions. The panel was assumed to be of E-glass random composite. The strips were assumed to be of three advanced unidirectional composites to cover a range of low, intermediate, and high modulus stiffness. The panels were assumed to be subjected to complex loadings to assess their adequacy as load-carrying members in auto body, aircraft engine nacelle and windmill blade applications. The results show that strip hybrid panels can be several times more structurally efficient than the random composite base materials. Some of the results are presented in graphical form and procedures are described for use of these graphs as guides for preliminary design of strip hybrids.

  14. Analysis/design of strip reinforced random composites /strip hybrids/

    Science.gov (United States)

    Chamis, C. C.; Sinclair, J. H.

    1978-01-01

    Results are described which were obtained by applying advanced analysis methods and composite mechanics to a strip-reinforced random composite square panel with fixed ends. This was done in order to illustrate the use of these methods for the apriori assessment of the composite panel when subjected to complex loading conditions. The panel was assumed to be of E-Glass/Random Composite. The strips were assumed to be of three advanced unidirectional composites to cover a range of low, intermediate, and high modulus stiffness. The panels were assumed to be subjected to complex loadings to assess their adequacy as load-carrying members in auto body, aircraft engine nacelle, and windmill blade applications. The results show that strip hybrid panels can be several times more structurally efficient than the random composite base materials. Some of the results are presented in graphical form and procedures are described for use of these graphs as guides for preliminary design of strip hybrids.

  15. Accuracy Analysis and Calibration of Gantry Hybrid Machine Tool

    Institute of Scientific and Technical Information of China (English)

    唐晓强; 李铁民; 尹文生; 汪劲松

    2003-01-01

    The kinematic accuracy is a key factor in the design of parallel or hybrid machine tools. This analysis improved the accuracy of a 4-DOF (degree of freedom) gantry hybrid machine tool based on a 3-DOF planar parallel manipulator by compensating for various positioning errors. The machine tool architecture was described with the inverse kinematic solution. The control parameter error model was used to analyze the accuracy of the 3-DOF planar parallel manipulator and to develop a kinematic calibration method. The experimental results prove that the calibration method reduces the cutter nose errors from ±0.50 mm to ±0.03 mm for a horizontal movement of 600 mm by compensating for errors in the slider home position, the guide way distance and the extensible strut home position. The calibration method will be useful for similar types of parallel kinematic machines.

  16. Plug-In Hybrid Vehicle Analysis (Milestone Report)

    Energy Technology Data Exchange (ETDEWEB)

    Markel, T.; Brooker, A.; Gonder, J.; O' Keefe, M.; Simpson, A.; Thornton, M.

    2006-11-01

    NREL's plug-in hybrid electric vehicle (PHEV) analysis activities made great strides in FY06 to objectively assess PHEV technology, support the larger U.S. Department of Energy PHEV assessment effort, and share technical knowledge with the vehicle research community and vehicle manufacturers. This report provides research papers and presentations developed in FY06 to support these efforts. The report focuses on the areas of fuel economy reporting methods, cost and consumption benefit analysis, real-world performance expectations, and energy management strategies.

  17. Hybrid Information Flow Analysis for Programs with Arrays

    Directory of Open Access Journals (Sweden)

    Gergö Barany

    2016-07-01

    Full Text Available Information flow analysis checks whether certain pieces of (confidential data may affect the results of computations in unwanted ways and thus leak information. Dynamic information flow analysis adds instrumentation code to the target software to track flows at run time and raise alarms if a flow policy is violated; hybrid analyses combine this with preliminary static analysis. Using a subset of C as the target language, we extend previous work on hybrid information flow analysis that handled pointers to scalars. Our extended formulation handles arrays, pointers to array elements, and pointer arithmetic. Information flow through arrays of pointers is tracked precisely while arrays of non-pointer types are summarized efficiently. A prototype of our approach is implemented using the Frama-C program analysis and transformation framework. Work on a full machine-checked proof of the correctness of our approach using Isabelle/HOL is well underway; we present the existing parts and sketch the rest of the correctness argument.

  18. Electric and Hybrid Vehicle System Research and Development Project: Hybrid Vehicle Potential Assessment. Volume VI. Cost analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hardy, K.S.

    1979-09-30

    The purpose of the cost analysis is to determine the economic feasibility of a variety of hybrid vehicles with respect to conventional vehicles specifically designed for the same duty cycle defined by the mission analysis. Several different hybrid configurations including parallel, parallel-flywheel, and series vehicles were evaluated. The ramifications of incorporating examples of advanced batteries, these being the advanced lead-acid, nickel-zinc, and sodium sulfur were also investigated. Vehicles were specifically designed with these batteries and for the driving cycles specified by the mission. Simulated operation on the missions yielded the energy consumption (petroleum and/or electricity) over the driving cycles. It was concluded that: in the event that gasoline prices reach $2.50 to $3.00/gal, hybrid vehicles in many applications will become economically competitive with conventional vehicles without subsidization; in some commercial applications hybrid vehicles could be economically competitive, when the gasoline price ranges from $1.20 to $1.50/gal. The cost per kWh per cycle of the advanced batteries is much more important economically than the specific energy; the series hybrid vehicles were found to be more expensive in comparison to the parallel or parallel-flywheel hybrids when designed as passenger vehicles; and hybrid vehicles designed for private use could become economically competitive and displace up to 50% of the fuel normally used on that mission if subsidies of $500 to $2000 were supplied to the owner/operator. (LCL)

  19. Analysis of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Wu, Hsi-Yung T.; Shaw, Peter; Przekop, Adam

    2013-01-01

    The hybrid wing body center section test article is an all-composite structure made of crown, floor, keel, bulkhead, and rib panels utilizing the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) design concept. The primary goal of this test article is to prove that PRSEUS components are capable of carrying combined loads that are representative of a hybrid wing body pressure cabin design regime. This paper summarizes the analytical approach, analysis results, and failure predictions of the test article. A global finite element model of composite panels, metallic fittings, mechanical fasteners, and the Combined Loads Test System (COLTS) test fixture was used to conduct linear structural strength and stability analyses to validate the specimen under the most critical combination of bending and pressure loading conditions found in the hybrid wing body pressure cabin. Local detail analyses were also performed at locations with high stress concentrations, at Tee-cap noodle interfaces with surrounding laminates, and at fastener locations with high bearing/bypass loads. Failure predictions for different composite and metallic failure modes were made, and nonlinear analyses were also performed to study the structural response of the test article under combined bending and pressure loading. This large-scale specimen test will be conducted at the COLTS facility at the NASA Langley Research Center.

  20. From hybridization theory to microarray data analysis: performance evaluation

    Directory of Open Access Journals (Sweden)

    Berger Fabrice

    2011-12-01

    Full Text Available Abstract Background Several preprocessing methods are available for the analysis of Affymetrix Genechips arrays. The most popular algorithms analyze the measured fluorescence intensities with statistical methods. Here we focus on a novel algorithm, AffyILM, available from Bioconductor, which relies on inputs from hybridization thermodynamics and uses an extended Langmuir isotherm model to compute transcript concentrations. These concentrations are then employed in the statistical analysis. We compared the performance of AffyILM and other traditional methods both in the old and in the newest generation of GeneChips. Results Tissue mixture and Latin Square datasets (provided by Affymetrix were used to assess the performances of the differential expression analysis depending on the preprocessing strategy. A correlation analysis conducted on the tissue mixture data reveals that the median-polish algorithm allows to best summarize AffyILM concentrations computed at the probe-level. Those correlation results are equivalent to the best correlations observed using popular preprocessing methods relying on intensity values. The performances of each tested preprocessing algorithm were quantified using the Latin Square HG-U133A dataset, thanks to the comparison of differential analysis results with the list of spiked genes. The figures of merit generated illustrates that the performances associated to AffyILM(medianpolish, inferred from the present statistical analysis, are comparable to the best performing strategies previously reported. Conclusions Converting probe intensities to estimates of target concentrations prior to the statistical analysis, AffyILM(medianpolish is one of the best performing strategy currently available. Using hybridization theory, probe-level estimates of target concentrations should be identically distributed. In the future, a probe-level multivariate analysis of the concentrations should be compared to the univariate analysis of

  1. Analysis of Non-binary Hybrid LDPC Codes

    CERN Document Server

    Sassatelli, Lucile

    2008-01-01

    In this paper, we analyse asymptotically a new class of LDPC codes called Non-binary Hybrid LDPC codes, which has been recently introduced. We use density evolution techniques to derive a stability condition for hybrid LDPC codes, and prove their threshold behavior. We study this stability condition to conclude on asymptotic advantages of hybrid LDPC codes compared to their non-hybrid counterparts.

  2. Analysis of high velocity impact on hybrid composite fan blades

    Science.gov (United States)

    Chamis, C. C.; Sinclair, J. H.

    1979-01-01

    This paper describes recent developments in the analysis of high velocity impact of composite blades using a computerized capability which consists of coupling a composites mechanics code with the direct-time integration features of NASTRAN. The application of the capability to determine the linear dynamic response of an intraply hybrid composite aircraft engine fan blade is described in detail. The predicted results agree with measured data. The results also show that the impact stresses reach sufficiently high magnitudes to cause failures in the impact region at early times of the impact event.

  3. Analysis and Design of Hybrid Excitation Permanent Magnet Synchronous Generators

    Institute of Scientific and Technical Information of China (English)

    JIN Wan-bing; ZHANG Dong; AN Zhong-liang; TAN Ren-yuan

    2006-01-01

    On the basis of a conventional permanent magnet (PM) synchronous generator's construction,a novel kind of Hybrid Excitation Permanent Magnet Synchronous Generator (HEPMSG) is introduced by inserting exciting winding in the stator or rotor.Firstly,the construction of HEPMSG is improved with the addition of PM excitation on the ferromagnetic pole,and its working principle and design method are studied in detail.Then,an appropriate exciting current control system is presented considering the characteristics of HEPMSG.Finally,a prototype is made,and test results confirm the analysis and design.

  4. Flow cytometry-based DNA hybridization and polymorphism analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cai, H.; Kommander, K.; White, P.S.; Nolan, J.P.

    1998-07-01

    Functional analysis of the humane genome, including the quantification of differential gene expression and the identification of polymorphic sites and disease genes, is an important element of the Human Genome Project. Current methods of analysis are mainly gel-based assays that are not well-suited to rapid genome-scale analyses. To analyze DNA sequence on a large scale, robust and high throughput assays are needed. The authors are developing a suite of microsphere-based approaches employing fluorescence detection to screen and analyze genomic sequence. The approaches include competitive DNA hybridization to measure DNA or RNA targets in unknown samples, and oligo ligation or extension assays to analyze single-nucleotide polymorphisms. Apart from the advances of sensitivity, simplicity, and low sample consumption, these flow cytometric approaches have the potential for high throughput multiplexed analysis using multicolored microspheres and automated sample handling.

  5. Analysis of plug-in hybrid electric vehicle utility factors

    Science.gov (United States)

    Bradley, Thomas H.; Quinn, Casey W.

    Plug-in hybrid electric vehicles (PHEVs) are hybrid electric vehicles that can be fueled from both conventional liquid fuels and grid electricity. To represent the total contribution of both of these fuels to the operation, energy use, and environmental impacts of PHEVs, researchers have developed the concept of the utility factor. As standardized in documents such as SAE J1711 and SAE J2841, the utility factor represents the proportion of vehicle distance travelled that can be allocated to a vehicle test condition so as to represent the real-world driving habits of a vehicle fleet. These standards must be used with care so that the results are understood within the context of the assumptions implicit in the standardized utility factors. This study analyzes and derives alternatives to the standard utility factors from the 2001 National Highway Transportation Survey, so as to understand the sensitivity of PHEV performance to assumptions regarding charging frequency, vehicle characteristics, driver characteristics, and means of defining the utility factor. Through analysis of these alternative utility factors, this study identifies areas where analysis, design, and policy development for PHEVs can be improved by alternative utility factor calculations.

  6. Hybrid Analysis Approach for Stochastic Response of Offshore Jacket Platforms

    Institute of Scientific and Technical Information of China (English)

    金伟良; 郑忠双; 李海波; 张立

    2000-01-01

    The dynamic response of offshore platforms is more serious in hostile sea environment than in shallow sea. In this paper, a hybrid solution combined with analytical and numerical method is proposed to compute the stochastic response of fixed offshore platforms to random waves, considering wave-structure interaction and non-linear drag force. The simulation program includes two steps: the first step is the eigenanalysis aspects associated the structure and the second step is response estimation based on spectral equations. The eigenanalysis could be done through conventional finite element method conveniently and its natural frequency and mode shapes obtained. In the second part of the process, the solution of the offshore structural response is obtained by iteration of a series of coupled spectral equations. Considering the third-order term in the drag force, the evaluation of the three-fold convolution should be demanded for nonlinear stochastic response analysis. To demonstrate this method, a numerical analysis is carried out for both linear and non-linear platform motions. The final response spectra have the typical two peaks in agreement with reality, indicating that the hybrid method is effective and can be applied to offshore engineering.

  7. Analysis of Network Parameters Influencing Performance of Hybrid Multimedia Networks

    Directory of Open Access Journals (Sweden)

    Dominik Kovac

    2013-10-01

    Full Text Available Multimedia networks is an emerging subject that currently attracts the attention of research and industrial communities. This environment provides new entertainment services and business opportunities merged with all well-known network services like VoIP calls or file transfers. Such a heterogeneous system has to be able satisfy all network and end-user requirements which are increasing constantly. Therefore the simulation tools enabling deep analysis in order to find the key performance indicators and factors which influence the overall quality for specific network service the most are highly needed. This paper provides a study on the network parameters like communication technology, routing protocol, QoS mechanism, etc. and their effect on the performance of hybrid multimedia network. The analysis was performed in OPNET Modeler environment and the most interesting results are discussed at the end of this paper

  8. Performance Analysis of Hybrid Electric Vehicle over Different Driving Cycles

    Science.gov (United States)

    Panday, Aishwarya; Bansal, Hari Om

    2017-02-01

    Article aims to find the nature and response of a hybrid vehicle on various standard driving cycles. Road profile parameters play an important role in determining the fuel efficiency. Typical parameters of road profile can be reduced to a useful smaller set using principal component analysis and independent component analysis. Resultant data set obtained after size reduction may result in more appropriate and important parameter cluster. With reduced parameter set fuel economies over various driving cycles, are ranked using TOPSIS and VIKOR multi-criteria decision making methods. The ranking trend is then compared with the fuel economies achieved after driving the vehicle over respective roads. Control strategy responsible for power split is optimized using genetic algorithm. 1RC battery model and modified SOC estimation method are considered for the simulation and improved results compared with the default are obtained.

  9. Experimental-numerical evaluation of a new butterfly specimen for fracture characterisation of AHSS in a wide range of stress states

    Science.gov (United States)

    Peshekhodov, I.; Jiang, S.; Vucetic, M.; Bouguecha, A.; Berhens, B.-A.

    2016-11-01

    Results of an experimental-numerical evaluation of a new butterfly specimen for fracture characterisation of AHHS sheets in a wide range of stress states are presented. The test on the new butterfly specimen is performed in a uniaxial tensile machine and provides sufficient data for calibration of common fracture models. In the first part, results of a numerical specimen evaluation are presented, which was performed with a material model of a dual-phase steel DP600 taken from literature with plastic flow and fracture descriptions. In the second part, results of an experimental-numerical specimen evaluation are shown, which was conducted on another dual-phase steel DP600, which was available with a description of plastic flow only and whose fracture behaviour was characterised in the frame of this work. The overall performance of the new butterfly specimen at different load cases with regard to characterisation of the fracture behaviour of AHSS was investigated. The dependency of the fracture strain on the stress triaxiality and Lode angle as well as space resolution is quantified. A parametrised CrachFEM ductile shear fracture model and modified Mohr-Coloumb ductile shear fracture model are presented as a result of this quantification. The test procedure and results analysis are believed to contribute to current discussions on requirements to AHSS fracture characterisation.

  10. BIOMETRIC ANALYSIS OF THE ARTIFICIAL HYBRIDIZATION BETWEEN Pangasius djambal BLEEKER, 1846 AND Pangasianodon hypophthalmus SAUVAGE, 1878

    Directory of Open Access Journals (Sweden)

    Rudhy Gustiano

    2016-10-01

    Full Text Available It is really important, since the possible use of these pangasiid hybrids in aquaculture faces the problem of potential impact on wild population. Therefore, it is urgently needed to provide quick identification tools in the field. This study investigated morphological characters of Pangasius djambal and Pangasianodon hypophthalmus and their hybrids. A detailed morphological analysis using 32 morphometric measurements and five meristic counts was done on the hybridization of P. djambal and P. hypophthalmus. Morphometric analysis and meristic counts showed that the reciprocal hybrids have intermediate characters except for gill raker number in which lower than that of parental species. In general, the hybrids have tendency to be like P. hypophthalmus rather than P. djambal. The only typical character of P. djambal appeared on hybrids is teeth shape, both vomerine and palatine. It is clearly defined that the true hybrids have seven pelvic fin rays.

  11. Fatigue Life Analysis of Tapered Hybrid Composite Flexbeams

    Science.gov (United States)

    Murri, Gretchen B.; Schaff, Jeffery R.; Dobyns, Alan L.

    2002-01-01

    Nonlinear-tapered flexbeam laminates from a full-size composite helicopter rotor hub flexbeam were tested under combined constant axial tension and cyclic bending loads. The two different graphite/glass hybrid configurations tested under cyclic loading failed by delamination in the tapered region. A 2-D finite element model was developed which closely approximated the flexbeam geometry, boundary conditions, and loading. The analysis results from two geometrically nonlinear finite element codes, ANSYS and ABAQUS, are presented and compared. Strain energy release rates (G) obtained from the above codes using the virtual crack closure technique (VCCT) at a resin crack location in the flexbeams are presented for both hybrid material types. These results compare well with each other and suggest that the initial delamination growth from the resin crack toward the thick region of the flexbeam is strongly mode II. The peak calculated G values were used with material characterization data to calculate fatigue life curves and compared with test data. A curve relating maximum surface strain to number of loading cycles at delamination onset compared reasonably well with the test results.

  12. Regulatory pathway analysis by high-throughput in situ hybridization.

    Directory of Open Access Journals (Sweden)

    Axel Visel

    2007-10-01

    Full Text Available Automated in situ hybridization enables the construction of comprehensive atlases of gene expression patterns in mammals. Such atlases can become Web-searchable digital expression maps of individual genes and thus offer an entryway to elucidate genetic interactions and signaling pathways. Towards this end, an atlas housing approximately 1,000 spatial gene expression patterns of the midgestation mouse embryo was generated. Patterns were textually annotated using a controlled vocabulary comprising >90 anatomical features. Hierarchical clustering of annotations was carried out using distance scores calculated from the similarity between pairs of patterns across all anatomical structures. This process ordered hundreds of complex expression patterns into a matrix that reflects the embryonic architecture and the relatedness of patterns of expression. Clustering yielded 12 distinct groups of expression patterns. Because of the similarity of expression patterns within a group, members of each group may be components of regulatory cascades. We focused on the group containing Pax6, an evolutionary conserved transcriptional master mediator of development. Seventeen of the 82 genes in this group showed a change of expression in the developing neocortex of Pax6-deficient embryos. Electromobility shift assays were used to test for the presence of Pax6-paired domain binding sites. This led to the identification of 12 genes not previously known as potential targets of Pax6 regulation. These findings suggest that cluster analysis of annotated gene expression patterns obtained by automated in situ hybridization is a novel approach for identifying components of signaling cascades.

  13. Design, analysis and modeling of a novel hybrid powertrain system based on hybridized automated manual transmission

    Science.gov (United States)

    Wu, Guang; Dong, Zuomin

    2017-09-01

    Hybrid electric vehicles are widely accepted as a promising short to mid-term technical solution due to noticeably improved efficiency and lower emissions at competitive costs. In recent years, various hybrid powertrain systems were proposed and implemented based on different types of conventional transmission. Power-split system, including Toyota Hybrid System and Ford Hybrid System, are well-known examples. However, their relatively low torque capacity, and the drive of alternative and more advanced designs encouraged other innovative hybrid system designs. In this work, a new type of hybrid powertrain system based hybridized automated manual transmission (HAMT) is proposed. By using the concept of torque gap filler (TGF), this new hybrid powertrain type has the potential to overcome issue of torque gap during gearshift. The HAMT design (patent pending) is described in details, from gear layout and design of gear ratios (EV mode and HEV mode) to torque paths at different gears. As an analytical tool, mutli-body model of vehicle equipped with this HAMT was built to analyze powertrain dynamics at various steady and transient modes. A gearshift was decomposed and analyzed based basic modes. Furthermore, a Simulink-SimDriveline hybrid vehicle model was built for the new transmission, driveline and vehicle modular. Control strategy has also been built to harmonically coordinate different powertrain components to realize TGF function. A vehicle launch simulation test has been completed under 30% of accelerator pedal position to reveal details during gearshift. Simulation results showed that this HAMT can eliminate most torque gap that has been persistent issue of traditional AMT, improving both drivability and performance. This work demonstrated a new type of transmission that features high torque capacity, high efficiency and improved drivability.

  14. Modeling and Analysis of Hybrid Dynamic Systems Using Hybrid Petri Nets

    OpenAIRE

    GHOMRI Latefa; Alla, Hassane

    2008-01-01

    Some extensions of PNs permitting HDS modeling were presented here. The first models to be presented are continuous PNs. This model may be used for modeling either a continuous system or a discrete system. In this case, it is an approximation that is often satisfactory. Hybrid PNs combine in the same formalism a discrete PN and a continuous PN. Two hybrid PN models were considered in this chapter. The first, called the hybrid PN, has a deterministic behavior; this means that we can predict th...

  15. Local analysis of hybrid systems on polyhedral sets with state-dependent switching

    Directory of Open Access Journals (Sweden)

    Leth John

    2014-06-01

    Full Text Available This paper deals with stability analysis of hybrid systems. Various stability concepts related to hybrid systems are introduced. The paper advocates a local analysis. It involves the equivalence relation generated by reset maps of a hybrid system. To establish a tangible method for stability analysis, we introduce the notion of a chart, which locally reduces the complexity of the hybrid system. In a chart, a hybrid system is particularly simple and can be analyzed with the use of methods borrowed from the theory of differential inclusions. Thus, the main contribution of this paper is to show how stability of a hybrid system can be reduced to a specialization of the well established stability theory of differential inclusions. A number of examples illustrate the concepts introduced in the paper.

  16. Performance Analysis of a Hybrid District Heating System

    DEFF Research Database (Denmark)

    Mikulandric, Robert; Krajačić, Goran; Duic, Neven

    2015-01-01

    Hybridisation of district heating systems can contribute to more efficient heat generation through cogeneration power plants or through the share increase of renewable energy sources in total energy consumption while reducing negative aspects of particular energy source utilisation. In this work......, the performance of a hybrid district energy system for a small town in Croatia has been analysed. Mathematical model for process analysis and optimisation algorithm for optimal system configuration has been developed and described. The main goal of the system optimisation is to reduce heat production costs....... Several energy sources for heat production have been considered in 8 different simulation cases. Simulation results show that the heat production costs could be reduced with introduction of different energy systems into an existing district heating system. Renewable energy based district heating systems...

  17. Second Year Analysis of a Hybrid Schedule High School

    Directory of Open Access Journals (Sweden)

    James B. Schreiber

    2001-11-01

    Full Text Available The current study examined two independent sophomore cohorts from a mid-western high school that had implemented a multi-schedule system (i.e., traditional, block, hybrid. The purpose of the study was to examine differences among the schedule types, gender, and GPA group on a state mandated standardized test. Analysis of covariance was used to examine the differences. Results indicate that a significant difference among schedule types was observed for only one cohort and for only one test (mathematics-computation. Results also indicate that schedule type did not significantly interact with gender or GPA group. The authors conclude that for these cohorts the type of schedule does not negatively or positively influence achievement.

  18. Seedling test and genetic analysis of white poplar hybrid clones

    Institute of Scientific and Technical Information of China (English)

    LI Bo; JIANG Xi-bing; ZHANG You-hui; ZHANG Zhi-yi; LI Shan-wen; AN Xin-min

    2008-01-01

    Cross breeding strategies are very efficient for gaining new and superior genotypes. Ninety-eight new white poplar hybrid clones produced from 12 cross combinations within the Section Leuce Duby were studied using genetic analysis and seedling tests. We exploited the wide variation that exists in this population and found that the differences among diameter at breast height (DBH), root collar diameter (RCD) and height (H) were statistically extremely significant. The repeatability of clones of these measured traits ranged from 0.947-0.967, which indicated that these Waits were strongly controlled by genetic factors. Based on multiple comparisons, a total of 25 clones showed better performance in growth than the conlrol cultivar. These 25 clones were from six different cross combinations, which can guarantee a larger genetic background for future new clone promotion projects. This study provides a simple overview on these clones and can guide us to carry out subsequent selection plans.

  19. ANALYSIS OF A TRANSPORT PROCESS USING HYBRID PETRI NETS

    Directory of Open Access Journals (Sweden)

    Elisabeta Mihaela CIORTEA

    2013-05-01

    Full Text Available Purpose of the paper is to analyze the Petri net model, to describe the transport process, part of amanufacturing system and its dynamics.A hibrid Petri net model is built to describe the dinamics of the transport process manufacturingsystem. Mathematical formulation of the dinamycs processes a detailed description. Based on this model, theanalysis of the transport process is designed to be able to execute a production plan and resolve any conflictsthat may arise in the system.In the analysis dinamics known two stages: in the continuous variables are discrete hybrid system in thehibrid discrete variables are used as safety control with very well defined responsibilities.In terms of the chosen model, analyze transport process is designed to help execute a production planand resolve conflicts that may arise in the process, and then the ones in the system

  20. Limit Cycle Analysis in a Class of Hybrid Systems

    Directory of Open Access Journals (Sweden)

    Antonio Favela-Contreras

    2016-01-01

    Full Text Available Hybrid systems are those that inherently combine discrete and continuous dynamics. This paper considers the hybrid system model to be an extension of the discrete automata associating a continuous evolution with each discrete state. This model is called the hybrid automaton. In this work, we achieve a mathematical formulation of the steady state and we show a way to obtain the initial conditions region to reach a specific limit cycle for a class of uncoupled and coupled continuous-linear hybrid systems. The continuous-linear term is used in the sense of the system theory and, in this sense, continuous-linear hybrid automata will be defined. Thus, some properties and theorems that govern the hybrid automata dynamic behavior to evaluate a limit cycle existence have been established; this content is explained under a theoretical framework.

  1. Improved Aerodynamic Analysis for Hybrid Wing Body Conceptual Design Optimization

    Science.gov (United States)

    Gern, Frank H.

    2012-01-01

    This paper provides an overview of ongoing efforts to develop, evaluate, and validate different tools for improved aerodynamic modeling and systems analysis of Hybrid Wing Body (HWB) aircraft configurations. Results are being presented for the evaluation of different aerodynamic tools including panel methods, enhanced panel methods with viscous drag prediction, and computational fluid dynamics. Emphasis is placed on proper prediction of aerodynamic loads for structural sizing as well as viscous drag prediction to develop drag polars for HWB conceptual design optimization. Data from transonic wind tunnel tests at the Arnold Engineering Development Center s 16-Foot Transonic Tunnel was used as a reference data set in order to evaluate the accuracy of the aerodynamic tools. Triangularized surface data and Vehicle Sketch Pad (VSP) models of an X-48B 2% scale wind tunnel model were used to generate input and model files for the different analysis tools. In support of ongoing HWB scaling studies within the NASA Environmentally Responsible Aviation (ERA) program, an improved finite element based structural analysis and weight estimation tool for HWB center bodies is currently under development. Aerodynamic results from these analyses are used to provide additional aerodynamic validation data.

  2. Analysis of chromosome aberration data by hybrid-scale models

    Energy Technology Data Exchange (ETDEWEB)

    Indrawati, Iwiq [Research and Development on Radiation and Nuclear Biomedical Center, National Nuclear Energy Agency (Indonesia); Kumazawa, Shigeru [Nuclear Technology and Education Center, Japan Atomic Energy Research Institute, Honkomagome, Tokyo (Japan)

    2000-02-01

    This paper presents a new methodology for analyzing data of chromosome aberrations, which is useful to understand the characteristics of dose-response relationships and to construct the calibration curves for the biological dosimetry. The hybrid scale of linear and logarithmic scales brings a particular plotting paper, where the normal section paper, two types of semi-log papers and the log-log paper are continuously connected. The hybrid-hybrid plotting paper may contain nine kinds of linear relationships, and these are conveniently called hybrid scale models. One can systematically select the best-fit model among the nine models by among the conditions for a straight line of data points. A biological interpretation is possible with some hybrid-scale models. In this report, the hybrid scale models were applied to separately reported data on chromosome aberrations in human lymphocytes as well as on chromosome breaks in Tradescantia. The results proved that the proposed models fit the data better than the linear-quadratic model, despite the demerit of the increased number of model parameters. We showed that the hybrid-hybrid model (both variables of dose and response using the hybrid scale) provides the best-fit straight lines to be used as the reliable and readable calibration curves of chromosome aberrations. (author)

  3. BIOMETRIC ANALYSIS OF THE ARTIFICIAL HYBRIDIZATION BETWEEN Pangasius djambal BLEEKER, 1846 AND Pangasianodon hypophthalmus SAUVAGE, 1878

    OpenAIRE

    Rudhy Gustiano

    2016-01-01

    It is really important, since the possible use of these pangasiid hybrids in aquaculture faces the problem of potential impact on wild population. Therefore, it is urgently needed to provide quick identification tools in the field. This study investigated morphological characters of Pangasius djambal and Pangasianodon hypophthalmus and their hybrids. A detailed morphological analysis using 32 morphometric measurements and five meristic counts was done on the hybridization of P. djambal and P....

  4. Analysis on Dry Matter Production Characteristics of Super Hybrid Rice

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Six middle-season indica hybrid rice combinations,including five super hybrid rice combinations with the high yield about 10.5 t/ha and a check hybrid rice combination Shanyou 63 with a yield potential about 9.5 t/ha,were used as materials to study the dry matter production characteristics.The super hybrid rice showed a high ability in dry matter production and accumulation and its yield enhanced with the increase of dry matter accumulation.The advantage period of dry matter production in the super hybrid rice was mainly at the middle and late growth stages compared with the check.The grain yield had no significant correlation with the dry matter accumulation before the elongation stage while had a significantly positive correlation with the dry matter accumulation from the elongation to maturity stages in super hybrid rice.There were more dry matter in vegetative organs at the heading stage in the super hybrid rice but its contribution to yield (apparent conversion percentage) was averagely 4.3 percent points lower than that in the check.For crop growth rate (CGR),the comparative advantage of super hybrid rice was at the middle and late stages,especially after flowering.Moreover,as the rising of leaf area index (LAI) and leaf area duration (LAD),CGR enhanced.The total LAD and the mean of LAD per day of super hybrid rice was about 14.79% and 10.31% higher than those of the check,respectively.The results indicate that the high yield of super hybrid rice mostly comes from the products of photosynthesis after heading,which is shown by the increased CGR at middle and later stages.It is suggested that LAD character might be used to better explain the advantage in the dry matter production of super hybrid rice than LAI.

  5. Simultaneous thermal analysis and thermodilatometry of hybrid fiber reinforced UHPC

    Science.gov (United States)

    Scheinherrová, Lenka; Fořt, Jan; Pavlík, Zbyšek; Černý, Robert

    2017-07-01

    Development of concrete technology and the availability of variety of materials such as silica fume, mineral microfillers and high-range water-reducing admixtures make possible to produce Ultra-High Performance Concrete (UHPC) with compressive strength higher than 160 MPa. However, UHPC is prone to spall under high temperatures what limits its use for special applications only, such as offshore and marine structures, industrial floors, security barriers etc. The spalling is caused by the thermal stresses due to the temperature gradient during heating, and by the splitting force owing to the release of water vapour. Hybrid fibre reinforcement based on combination of steel and polymer fibres is generally accepted by concrete community as a functional solution preventing spalling. In this way, Ultra-High Performance Fibre Reinforced Concrete (UHPFRC) is produced possessing high mechanical strength, durability and resistance to water and salt ingress. Since UHPFRC find use in construction industry in tunnel linings, precast tunnel segments, and high-rise buildings, its behaviour during the high-temperature exposure and its residual parameters are of the particular importance. On this account, Simultaneous Thermal Analysis (STA) and Thermodilatometry Analysis (TDA) were done in the paper to identify the structural and chemical changes in UHPFRC during its high-temperature load. Based on the experimental results, several physical and chemical processes that studied material underwent at high-temperatures were recognized. The obtained data revealed changes in the composition of the studied material and allowed identification of critical temperatures for material damage.

  6. Analysis of SMA Hybrid Composite Structures using Commercial Codes

    Science.gov (United States)

    Turner, Travis L.; Patel, Hemant D.

    2004-01-01

    A thermomechanical model for shape memory alloy (SMA) actuators and SMA hybrid composite (SMAHC) structures has been recently implemented in the commercial finite element codes MSC.Nastran and ABAQUS. The model may be easily implemented in any code that has the capability for analysis of laminated composite structures with temperature dependent material properties. The model is also relatively easy to use and requires input of only fundamental engineering properties. A brief description of the model is presented, followed by discussion of implementation and usage in the commercial codes. Results are presented from static and dynamic analysis of SMAHC beams of two types; a beam clamped at each end and a cantilevered beam. Nonlinear static (post-buckling) and random response analyses are demonstrated for the first specimen. Static deflection (shape) control is demonstrated for the cantilevered beam. Approaches for modeling SMAHC material systems with embedded SMA in ribbon and small round wire product forms are demonstrated and compared. The results from the commercial codes are compared to those from a research code as validation of the commercial implementations; excellent correlation is achieved in all cases.

  7. User-interfaces for hybrid systems: Analysis and design through hybrid reachability

    Science.gov (United States)

    Oishi, Meeko Mitsuko Karen

    Hybrid systems combine discrete state dynamics, which model mode switching, with continuous state dynamics, which model the physical processes themselves. Applications of hybrid system theory to automated systems have traditionally assumed that the controller itself is an automaton which runs in parallel with the system under control. We model human interaction with hybrid systems, which involves the user; the automation's discrete mode-logic, and the underlying continuous dynamics of the physical system. Often in safety-critical systems, user-interfaces display a reduced set of information about the entire system, however must still provide adequate information and must not confuse the user. We present (1) a method of designing a discrete event system abstraction of the hybrid system, in order to verify or design user-interfaces for hybrid human-automation systems, and (2) the relationship between user-interfaces and discrete observability properties. Using a hybrid computational tool for reachability, we find the largest region in which the system can always remain---this is the safe region of operation. By implementing a controller which arises from this computation, we mathematically guarantee that this safe region is invariant. Assigning discrete states to the computed invariant regions, we create a discrete event system from this hybrid system with safety restrictions. This abstraction can then be used in existing interface verification and design methods. A user-interface, modeled as a discrete system, must, not only be reduced (extraneous information has been eliminated), but also "immediately observable". We derive conditions for immediate observability, in which the current state can be constructed from the current output and last occurring event. Based on finite state machine state-reduction techniques, we synthesize an output for remote user-interfaces which fulfills this property. Aircraft are prime examples of complex, safety-critical systems. In

  8. Computational analysis on plug-in hybrid electric motorcycle chassis

    Science.gov (United States)

    Teoh, S. J.; Bakar, R. A.; Gan, L. M.

    2013-12-01

    Plug-in hybrid electric motorcycle (PHEM) is an alternative to promote sustainability lower emissions. However, the PHEM overall system packaging is constrained by limited space in a motorcycle chassis. In this paper, a chassis applying the concept of a Chopper is analysed to apply in PHEM. The chassis 3dimensional (3D) modelling is built with CAD software. The PHEM power-train components and drive-train mechanisms are intergraded into the 3D modelling to ensure the chassis provides sufficient space. Besides that, a human dummy model is built into the 3D modelling to ensure the rider?s ergonomics and comfort. The chassis 3D model then undergoes stress-strain simulation. The simulation predicts the stress distribution, displacement and factor of safety (FOS). The data are used to identify the critical point, thus suggesting the chassis design is applicable or need to redesign/ modify to meet the require strength. Critical points mean highest stress which might cause the chassis to fail. This point occurs at the joints at triple tree and bracket rear absorber for a motorcycle chassis. As a conclusion, computational analysis predicts the stress distribution and guideline to develop a safe prototype chassis.

  9. Hybrid pairwise likelihood analysis of animal behavior experiments.

    Science.gov (United States)

    Cattelan, Manuela; Varin, Cristiano

    2013-12-01

    The study of the determinants of fights between animals is an important issue in understanding animal behavior. For this purpose, tournament experiments among a set of animals are often used by zoologists. The results of these tournament experiments are naturally analyzed by paired comparison models. Proper statistical analysis of these models is complicated by the presence of dependence between the outcomes of fights because the same animal is involved in different contests. This paper discusses two different model specifications to account for between-fights dependence. Models are fitted through the hybrid pairwise likelihood method that iterates between optimal estimating equations for the regression parameters and pairwise likelihood inference for the association parameters. This approach requires the specification of means and covariances only. For this reason, the method can be applied also when the computation of the joint distribution is difficult or inconvenient. The proposed methodology is investigated by simulation studies and applied to real data about adult male Cape Dwarf Chameleons. © 2013, The International Biometric Society.

  10. Performance analysis of switching based hybrid FSO/RF transmission

    KAUST Repository

    Usman, Muneer

    2014-09-01

    Hybrid free space optical (FSO)/ radio frequency (RF) systems have emerged as a promising solution for high data rate wireless back haul.We present and analyze a switching based transmission scheme for hybrid FSO/RF system. Specifically, either FSO or RF link will be active at a certain time instance, with FSO link enjoying a higher priority. Analytical expressions have been obtained for the outage probability, average bit error rate and ergodic capacity for the resulting system. Numerical examples are presented to compare the performance of the hybrid scheme with FSO only scenario.

  11. Genetic analysis of agro-morphological traits in promising hybrids of sunflower (Helianthus annuus L.

    Directory of Open Access Journals (Sweden)

    Maryam GOLABADI

    2015-11-01

    Full Text Available The main objective underlying sunflower breeding programs is to develop high-yielding productive F1 hybrid cultivars. This study was conducted to investigate the genetic control of some agro-morphological traits of new sunflower F1 hybrids. For this purpose, fourteen inbred lines of sunflower were crossed with three male sterile inbred lines. Their hybrids (14 hybrids were then evaluated against three control cultivars. The data thus obtained were analyzed using the nested model (North Carolina Design І as a completely randomized block design (CRBD with four replications. Analysis of variance showed that the hybrids were significantly different in all the traits studied, except for head and stem diameters. From among the hybrids evaluated, Cms19 × Rn1-81 was found to have the highest seed yield and oil content. Cluster analysis classified the hybrids into four different groups. Genetic analysis showed that days to maturity, seed weight, and oil content (% were under the additive gene action. Breeding strategies based on selection could be suggested for the improvement of these traits. Head angle, head diameter, seed yield, and oil yield were under the dominance gene action; breeding based on hybridization methods is, therefore, proposed for these traits. Finally, both additive and dominance gene actions were observed to play important roles in the genetic control of plant height and stem diameter.

  12. Experimental, Numerical and Analytical Characterization of Slosh Dynamics Applied to In-Space Propellant Storage, Management and Transfer

    Science.gov (United States)

    Storey, Jedediah M.; Kirk, Daniel; Gutierrez, Hector; Marsell, Brandon; Schallhorn, Paul; Lapilli, Gabriel D.

    2015-01-01

    Experimental and numerical results are presented from a new cryogenic fluid slosh program at the Florida Institute of Technology (FIT). Water and cryogenic liquid nitrogen are used in various ground-based tests with an approximately 30 cm diameter spherical tank to characterize damping, slosh mode frequencies, and slosh forces. The experimental results are compared to a computational fluid dynamics (CFD) model for validation. An analytical model is constructed from prior work for comparison. Good agreement is seen between experimental, numerical, and analytical results.

  13. Comparative genomic in situ hybridization analysis on the ...

    African Journals Online (AJOL)

    AJL

    2012-04-10

    Apr 10, 2012 ... different parents/ancestors/genomes in hybrid plants to be distinguished ... sequences in common between the two species. Therefore, cGISH ... genomic organization and genome evolution in plants. (Zoller et al., 2001).

  14. Synchronizability Analysis of Harmonious Unification Hybrid Preferential Model

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The harmonious unification hybrid preferential model uses the dr ratio to adjust the proportion of deterministic preferential attachment and random preferential attachment, enriched the only deterministic preferential network model,

  15. SIMS: a hybrid method for rapid conformational analysis.

    Directory of Open Access Journals (Sweden)

    Bryant Gipson

    Full Text Available Proteins are at the root of many biological functions, often performing complex tasks as the result of large changes in their structure. Describing the exact details of these conformational changes, however, remains a central challenge for computational biology due the enormous computational requirements of the problem. This has engendered the development of a rich variety of useful methods designed to answer specific questions at different levels of spatial, temporal, and energetic resolution. These methods fall largely into two classes: physically accurate, but computationally demanding methods and fast, approximate methods. We introduce here a new hybrid modeling tool, the Structured Intuitive Move Selector (sims, designed to bridge the divide between these two classes, while allowing the benefits of both to be seamlessly integrated into a single framework. This is achieved by applying a modern motion planning algorithm, borrowed from the field of robotics, in tandem with a well-established protein modeling library. sims can combine precise energy calculations with approximate or specialized conformational sampling routines to produce rapid, yet accurate, analysis of the large-scale conformational variability of protein systems. Several key advancements are shown, including the abstract use of generically defined moves (conformational sampling methods and an expansive probabilistic conformational exploration. We present three example problems that sims is applied to and demonstrate a rapid solution for each. These include the automatic determination of "active" residues for the hinge-based system Cyanovirin-N, exploring conformational changes involving long-range coordinated motion between non-sequential residues in Ribose-Binding Protein, and the rapid discovery of a transient conformational state of Maltose-Binding Protein, previously only determined by Molecular Dynamics. For all cases we provide energetic validations using well

  16. Design and Analysis of the AlNiCo Hybrid Magnet in EMS Maglev Vehicles

    Directory of Open Access Journals (Sweden)

    Lv Chao

    2017-01-01

    Full Text Available In order to solve the problem of hybrid electromagnet lock orbit, we design a new type of AlNiCo-NdFeB hybrid levitation electromagnet. The theoretical analysis has be carried on and mathematical model is established for AlNiCo-NdFeB hybrid levitation electromagnet. Through two dimensional simulation, the electromagnetic characteristics of the suspended electromagnet are analyzed in the 3 typical operating conditions , which are in heavy load at gap 8mm, in full load at gap 16mm and in no-load at gap 3mm. And it’s compared with the traditional electromagnetic magnet and NdFeB hybrid electromagnet. Calculation and analysis show that the new hybrid levitation electromagnet can effectively solve the problems of the electromagnet lock orbit, at the same time, have a good dynamic performance and suspension regulation performance.

  17. Site-specific analysis of hybrid geothermal/fossil power plants

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-01

    A preliminary economic analysis of a hybrid geothermal/coal power plant has been completed for four geothermal Resource areas: Roosevelt Hot Springs, Coso Hot Springs, East Mesa and Long Valley. A hybrid plant would be economically viable at Roosevelt Hot Springs and somewhat less so at Coso Hot Springs. East Mesa and Long Valley show no economic promise. A well-designed hybrid plant could use geothermal energy for boiler feedwater heating, auxiliary power, auxiliary heating, and cooling water. Construction and operation of a hybrid plant at either Roosevelt Hot Springs or Coso Hot Springs is recommended. Brown University provided the theoretical basis for the hybrid study. A modified version of the Lawrence Berkeley Livermore GEOTHM Program is the major analytical tool used in the analysis. The Intermountain Power Project is the reference all coal-fired plant. Costing methods followed recommendations issued by the Energy research and Development Administration.

  18. Evaluation of new NS maize hybrids using biplot analysis

    Directory of Open Access Journals (Sweden)

    Stojaković Milisav

    2012-01-01

    Full Text Available The study analyzed two-year results of a testing of 20 new maize hybrids from FAO MG 600 as compared to a standard. Data on the hybrids NS6683, NS6686, NS281633, and NS396432 are discussed in the paper in greater detail. In order to study grain yield, grain moisture, root and stalk lodging, and resistance to pests and diseases, field trials using a RCB design with four replicates were conducted in six locations in 2009 and five locations in 2010. The results were presented in the form of GGE biplots in order to rank hybrids relative to the standard while taking into account the genotype x environment interaction and to identify the highest-yielding genotypes in different environments. It was determined that the new NS hybrids had higher grain yield than the standard by 0.883 to 1.720 tha-1, lower grain moisture by 0.85 to 2.54%, better tolerance to root and stalk lodging, and pest and disease resistance on a par to the standard. The study identified so-called ideal locations for particular hybrids, which may be of use when determining which areas the hybrids are best suited for.

  19. Genetic molecular analysis of Coffea arabica (Rubiaceae hybrids using SRAP markers

    Directory of Open Access Journals (Sweden)

    Manoj Kumar Mishra

    2011-06-01

    Full Text Available In Coffea arabica (arabica coffee, the phenotypic as well as genetic variability has been found low because of the narrow genetic basis and self fertile nature of the species. Because of high similarity in phenotypic appearance among the majority of arabica collections, selection of parental lines for inter-varietals hybridization and identification of resultant hybrids at an early stage of plant growth is difficult. DNA markers are known to be reliable in identifying closely related cultivars and hybrids. Sequence Related Amplified Polymorphism (SRAP is a new molecular marker technology developed based on PCR. In this paper, sixty arabica-hybrid progenies belonging to six crosses were analyzed using 31 highly polymorphic SRAP markers. The analysis revealed seven types of SRAP marker profiles which are useful in discriminating the parents and hybrids. The number of bands amplified per primer pair ranges from 6.13 to 8.58 with average number of seven bands. Among six hybrid combinations, percentage of bands shared between hybrids and their parents ranged from 66.29% to 85.71% with polymorphic bands varied from 27.64% to 60.0%. Percentage of hybrid specific fragments obtained in various hybrid combinations ranged from 0.71% to 10.86% and ascribed to the consequence of meiotic recombination. Based on the similarity index calculation, it was observed that F1 hybrids share maximum number of bands with the female parent compared to male parent. The results obtained in the present study revealed the effectiveness of SRAP technique in cultivar identification and hybrid analysis in this coffee species. Rev. Biol. Trop. 59 (2: 607-617. Epub 2011 June 01.

  20. Hybrid-Electric and All-Electric Rotorcraft Analysis and Tool Development Project

    Data.gov (United States)

    National Aeronautics and Space Administration — During this Phase I effort ESAero will draw upon its knowledge of hybrid-electric propulsion system design and analysis for fixed wing aircraft to investigate the...

  1. A generalized hybrid transfinite element computational approach for nonlinear/linear unified thermal/structural analysis

    Science.gov (United States)

    Tamma, Kumar K.; Railkar, Sudhir B.

    1987-01-01

    The present paper describes the development of a new hybrid computational approach for applicability for nonlinear/linear thermal structural analysis. The proposed transfinite element approach is a hybrid scheme as it combines the modeling versatility of contemporary finite elements in conjunction with transform methods and the classical Bubnov-Galerkin schemes. Applicability of the proposed formulations for nonlinear analysis is also developed. Several test cases are presented to include nonlinear/linear unified thermal-stress and thermal-stress wave propagations. Comparative results validate the fundamental capablities of the proposed hybrid transfinite element methodology.

  2. In situ hybridization analysis of isodicentric X-chromosomes with short arm fusion

    DEFF Research Database (Denmark)

    Koch, J E; Kølvraa, S; Hertz, Jens Michael;

    1990-01-01

    We present here an alternative approach to the study of mosaic cell lines containing dicentric chromosomes. The approach is based on chromosome-specific non-radioactive in situ hybridization with centromere (alpha satellite DNA) probes. The hybridization analysis may be used as an alternative...... it for the analysis of two cases of isodicentric X-chromosomes. The approach is expected to be generally applicable, so that it may be applied to the scoring of other types of chromosomal mosaicism as well....

  3. Parallel Hybrid Gas-Electric Geared Turbofan Engine Conceptual Design and Benefits Analysis

    Science.gov (United States)

    Lents, Charles; Hardin, Larry; Rheaume, Jonathan; Kohlman, Lee

    2016-01-01

    The conceptual design of a parallel gas-electric hybrid propulsion system for a conventional single aisle twin engine tube and wing vehicle has been developed. The study baseline vehicle and engine technology are discussed, followed by results of the hybrid propulsion system sizing and performance analysis. The weights analysis for the electric energy storage & conversion system and thermal management system is described. Finally, the potential system benefits are assessed.

  4. GeoNeoLogical novel and other hybrimedia experiments: or how to use hybrid methods such as Hybrid Discourse Analysis (HDA within a knowledge base

    Directory of Open Access Journals (Sweden)

    Andrade, Pedro

    2016-07-01

    Full Text Available In this essay I will present some results of the project Public Communication of Art, which developed a seminal theory and methodology intended to cope with hybridity and new media literacy in our globalized and inter/transcultural world. Some of the methods used blend vision with touch and are called ‘hybrid methods’ or ‘hybrimethods’. Examples of these are, for instance, a Multitouch Interactive Table, a Multitouch Questionnaire, Trichotomies Game and GeoNeoLogic Novel, this last one being a hybrid novel activated by fusion of vision, touch and GPS coordinates. Another hybrimethod is a sort of discursive analysis, named Hybrid Discourse Analysis (HDA, which uses ‘semantic-logical networks’ organized by concepts and ‘relation-concepts’. HDA is here articulated with Critical Sociology and applied to the analysis of a text on Magic Realism, which is also a hybrid genre within the social field of literature.

  5. Multi-channel Hybrid Access Femtocells: A Stochastic Geometric Analysis

    CERN Document Server

    Zhong, Yi

    2011-01-01

    For two-tier networks consisting of macrocells and femtocells, the channel access mechanism can be configured to be open access, closed access, or hybrid access. Hybrid access arises as a compromise between open and closed access mechanisms, in which a fraction of available spectrum resource is shared to nonsubscribers while the remaining reserved for subscribers. This paper focuses on a hybrid access mechanism for multi-channel femtocells which employ orthogonal spectrum access schemes. Considering a randomized channel assignment strategy, we analyze the performance in the downlink. Using stochastic geometry as technical tools, we derive the distributions of signal-to-interference-plus-noise ratios, and mean achievable rates, of both nonsubscribers and subscribers. The established expressions are amenable to numerical evaluation, and shed key insights into the performance tradeoff between subscribers and nonsubscribers. The analytical results are corroborated by numerical simulations.

  6. Analysis of advanced solar hybrid desiccant cooling systems for buildings

    Energy Technology Data Exchange (ETDEWEB)

    Schlepp, D.; Schultz, K.

    1984-10-01

    This report describes an assessment of the energy savings possible from developing hybrid desiccant/vapor-compression air conditioning systems. Recent advances in dehumidifier design for solar desiccant cooling systems have resulted in a dehumidifier with a low pressure drop and high efficiency in heat and mass transfer. A recent study on hybrid desiccant/vapor compression systems showed a 30%-80% savings in resource energy when compared with the best conventional systems with vapor compression. A system consisting of a dehumidifier with vapor compression subsystems in series was found to be the simplest and best overall performer.

  7. Phenotypic and Genotypic Analysis of Newly Obtained Interspecific Hybrids in the Campanula Genus

    Science.gov (United States)

    Röper, Anna-Catharina; Orabi, Jihad; Lütken, Henrik; Christensen, Brian; Thonning Skou, Anne-Marie; Müller, Renate

    2015-01-01

    Interspecific hybridisation creates new phenotypes within several ornamental plant species including the Campanula genus. We have employed phenotypic and genotypic methods to analyse and evaluate interspecific hybridisation among cultivars of four Campanula species, i.e. C. cochleariifolia, C. isophylla, C. medium and C. formanekiana. Hybrids were analysed using amplified fragment length polymorphism (AFLP), flow cytometry and biometrical measurements. Results of correlation matrices demonstrated heterogeneous phenotypes for the parental species, which confirmed our basic premise for new phenotypes of interspecific hybrids. AFLP assays confirmed the hybridity and identified self-pollinated plants. Limitation of flow cytometry analysis detection was observed while detecting the hybridity status of two closely related parents, e.g. C. cochleariiafolia × C. isophylla. Phenotypic characteristics such as shoot habitus and flower colour were strongly influenced by one of the parental species in most crosses. Rooting analysis revealed that inferior rooting quality occurred more often in interspecific hybrids than in the parental species. Only interspecific hybrid lines of C. formanekiana ‘White’ × C. medium ‘Pink’ showed a high rooting level. Phenotype analyses demonstrated a separation from the interspecific hybrid lines of C. formanekiana ‘White’ × C. medium ‘Pink’ to the other clustered hybrids of C. formanekiana and C. medium. In our study we demonstrated that the use of correlation matrices is a suitable tool for identifying suitable cross material. This study presents a comprehensive overview for analysing newly obtained interspecific hybrids. The chosen methods can be used as guidance for analyses for further interspecific hybrids in Campanula, as well as in other ornamental species. PMID:26352688

  8. Genetic analysis of hybridization and introgression between wild mongoose and brown lemurs

    Directory of Open Access Journals (Sweden)

    Nievergelt Caroline M

    2009-02-01

    Full Text Available Abstract Background Hybrid zones generally represent areas of secondary contact after speciation. The nature of the interaction between genes of individuals in a hybrid zone is of interest in the study of evolutionary processes. In this study, data from nuclear microsatellites and mitochondrial DNA sequences were used to genetically characterize hybridization between wild mongoose lemurs (Eulemur mongoz and brown lemurs (E. fulvus at Anjamena in west Madagascar. Results Two segments of mtDNA have been sequenced and 12 microsatellite loci screened in 162 brown lemurs and mongoose lemurs. Among the mongoose lemur population at Anjamena, we identified two F1 hybrids (one also having the mtDNA haplotype of E. fulvus and six other individuals with putative introgressed alleles in their genotype. Principal component analysis groups both hybrids as intermediate between E. mongoz and E. fulvus and admixture analyses revealed an admixed genotype for both animals. Paternity testing proved one F1 hybrid to be fertile. Of the eight brown lemurs genotyped, all have either putative introgressed microsatellite alleles and/or the mtDNA haplotype of E. mongoz. Conclusion Introgression is bidirectional for the two species, with an indication that it is more frequent in brown lemurs than in mongoose lemurs. We conclude that this hybridization occurs because mongoose lemurs have expanded their range relatively recently. Introgressive hybridization may play an important role in the unique lemur radiation, as has already been shown in other rapidly evolving animals.

  9. Ray analysis of a class of hybrid cylindrical aircraft wings

    OpenAIRE

    Jha, RM; Bokhari, SA; Sudhakan, V; Mahapatra, PR

    1988-01-01

    A new approach to the modelling of aircraft wings, based on the combination of hybrid quadric (parabolic and circular) cylinders, has been presented for electromagnetic applications. Closed-form expressions have been obtained for ray parameters required in the high-frequency mutual coupling computation of antenna pairs located arbitrarily on an aircraft wing.

  10. Design and Analysis of Hybrid CMOS SRAM Sense Amplifier

    Directory of Open Access Journals (Sweden)

    Karishma Bajaj

    2012-03-01

    Full Text Available Sense amplifiers are one of the very important peripheral components of CMOS memories. In a Hybrid Sense amplifier both current and voltage sensing techniques are used which makes it a better selection than a conventional current or voltage sense amplifiers. The hybrid sense amplifier works in three phases-Offset cancellation (200ps, Access phase (500ps and Evaluation phase. The offset cancellation is done simultaneously with word line decoding, so as to speed up the process. The sensing range of the hybrid sense amplifier is improved from 1.18mV to 92mV. Also hybrid sense amplifier consumes very low energy of about 6.84fj. This sense amplifier is analyzed with a column of 512 SRAM cells at 180nm technology node and compared to CMOS conventional voltage sense amplifier. The circuit consumes an average power of 1.57 µW with a negligible offset of 149.3µV.

  11. Sensorless Suitability Analysis of Hybrid PM Machines for Electric Vehicles

    DEFF Research Database (Denmark)

    Matzen, Torben Nørregaard; Rasmussen, Peter Omand

    2009-01-01

    Electrical machines for traction in electric vehicles are an essential component which attract attention with respect to machine design and control as a part of the emerging renewable industry. For the hybrid electric machine to replace the familiar behaviour of the combustion engine torque...

  12. Combined analysis of cervical smears. Cytopathology, image cytometry and in situ hybridization

    DEFF Research Database (Denmark)

    Multhaupt, H; Bruder, E; Elit, L

    1993-01-01

    This study was an attempt to correlate the Bethesda System of Papanicolaou smear classification with DNA content by image analysis and the presence of human papillomavirus (HPV) as determined by in situ hybridization. DNA histograms were classified as normal diploid, diploid proliferative......, polyploid and aneuploid. HPV in situ hybridization was performed with a cocktail of probes specific to HPV types 6, 11, 16 and 18. There was a good correlation between normal cytology and normal DNA histograms. Cytologically normal smears with bacterial or fungal infections showed a high proliferation index....... Four of five cases cytologically suspicious for HPV infection had HPV by in situ hybridization....

  13. APPLICATION OF PENALTY FUNCTION METHOD IN ISOPARAMETRIC HYBRID FINITE ELEMENT ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    CHEN Dao-zheng; JIAO Zhao-ping

    2005-01-01

    By the aid of the penalty function method, the equilibrium restriction conditions were introduced to the isoparametric hybrid finite element analysis, and the concrete application course of the penalty function method in three-dimensional isoparametric hybrid finite element was discussed. The separated penalty parameters method and the optimal hybrid element model with penalty balance were also presented.The penalty balance method can effectively refrain the parasitical stress on the premise of no additional degrees of freedom. The numeric experiment shows that the presented element not only is effective in improving greatly the numeric calculation precision of distorted grids but also has the universality.

  14. Evaluation of genotype x environment interactions in maize hybrids using GGE biplot analysis

    Directory of Open Access Journals (Sweden)

    Fatma Aykut Tonk

    2011-01-01

    Full Text Available Seventeen hybrid maize genotypes were evaluated at four different locations in 2005 and 2006 cropping seasonsunder irrigated conditions in Turkey. The analysis of variance showed that mean squares of environments (E, genotypes (G andGE interactions (GEI were highly significant and accounted for 74, 7 and 19 % of treatment combination sum squares, respectively.To determine the effects of GEI on grain yield, the data were subjected to the GGE biplot analysis. Maize hybrid G16 can be proposedas reliably growing in test locations for high grain yield. Also, only the Yenisehir location could be best representative of overalllocations for deciding about which experimental hybrids can be recommended for grain yield in this study. Consequently, using ofgrain yield per plant instead of grain yield per plot in hybrid maize breeding programs could be preferred by private companies dueto some advantages.

  15. Biometric analysis of interspecific hybrids between Rosa canina L. and Rosa rubiginosa L. (section Caninae DC. em. Christ.

    Directory of Open Access Journals (Sweden)

    Anna Sołtys-Lelek

    2016-06-01

    Full Text Available The article presents the biometric analysis of selected morphological features of interspecies hybrid Rosa canina L. × R. rubiginosa L. This hybrid was the result of spontaneous hybridization between the two species falling into section Caninae DC. em. Christ. So far, it has not been studied in terms of morphological characteristics, in particular with respect to the parental forms.

  16. Design and analysis of a wheel-legged hybrid locomotion mechanism

    Directory of Open Access Journals (Sweden)

    Change Zheng

    2015-11-01

    Full Text Available A wheel-legged hybrid robot was put forward. First, the mechanical design of this chassis was introduced. Second, based on the kinematic analysis, comparison between the robot with the active transition system and that with the passive transition system was made. Third, the process of overcoming three kinds of obstacles was simulated. Finally, the conclusion can be made that this hybrid locomotion mechanism with the active transition system has good performance on rough terrains.

  17. Periodically-Scheduled Controller Analysis using Hybrid Systems Reachability and Continuization

    Science.gov (United States)

    2015-12-01

    algorithm is run, and actuator outputs are set. The physical world , on the other hand, evolves continuously. Models of the physical world may be given...An extra clock variable, c, is added to the hybrid automaton that ticks at rate one (ċ = 1). When the clock reaches the period, a transition is...Preliminary Reachability Analysis Although hybrid automata can model real-time scheduled controllers and plants as shown above, an important factor is

  18. Analysis of genetic diversity of maize hybrids in the regional tests in Sichuan and Southwest China

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In this study,analyses of phenotypic characters,SSR molecular markers and pedigrees were done to study the genetic diversity in 186 maize hybrids that were tested in regional trials in Sichuan and Southwest China.The results showed that there were differences in the variation coefficients of different characteristics,but all of the variation coefficients changed within a narrow range.Sixty pairs of simple sequence repeat (SSR) primer distributed on the ten chromosomes of maize produced stable amplified bands and 608 alleles were detected among the hybrids.The average number of alleles per locus was 10.1 ranging from 3 to 23.The values of polymorphism information content (PIC) for each SSR locus varied from 0.5179 to 0.9256 with an average of 0.7826.The genetic similarities of SSR marker pattern among the 186 hybrids ranged from 0.6067 to 0.9162,with an average of 0.7722.There were 16499 pairs of genetic similarity,in which 96.9% were 0.70000 to 0.9256.The cluster analysis showed that the hybrids could be classified into ten clusters,with 88.2% of the hybrids included in Cluster 4,Cluster 8 and Cluster 10.The analysis of pedigree sources of 51 hybrids showed that 36 hybrids had close genetic relationships with the hybrids developed by the Pioneer Company in the late 1980s and early 1990s in the United States,such as Y78599,Y7865 and Y78698,accounting for 70.58%.Meanwhile,13 hybrids had close genetic relationships with Y78599,accounting for 8.66%.The genetic similarities of SSR marker pattern among the 51 hybrids ranged from 0.66192 to 0.8799,with an average of 0.7686.There were 1196 pairs of genetic similarity ranged between 0.7000 to 0.8796,accounting for 93.80% of all the genetic similarity pairs.The cluster analysis showed that 88.2% of the 51 hybrids were in Cluster 4,Cluster 8 and Cluster 10,which indicated that similarity was high and genetic diversity narrow among the 186 hybrids.This showed that it is necessary to broaden the genetic basis of breeding

  19. Thermal analysis of solar biomass hybrid co-generation plants

    Science.gov (United States)

    Kaushika, N. D.; Mishra, Anuradha; Chakravarty, M. N.

    2005-12-01

    This article describes a co-generation plant based on the biogas being produced from the waste of distillery plant and highlights the possible configuration in which the plant can be hybridized with auxiliary solar energy source having the advantage of using financial incentives in several countries. In hybridization, the solar heat is used for heating the boiler feed water. The solar heat-generating unit consists of line focus parabolic trough collector, heat transportation system and heat delivery unit such as heat exchanger. The simulation model of heat and mass transfer processes in the solar field as well as the balance of the system is developed to investigate the technological feasibility of the concept in terms of plant yield and matching of subsystems.

  20. Capacity analysis of inhomogeneous hybrid wireless networks using directional antennas

    Institute of Scientific and Technical Information of China (English)

    WU Feng; ZHU Jiang; TIAN Yi-long; ZOU Jian-bin

    2016-01-01

    Most of studies on network capacity are based on the assumption that all the nodes are uniformly distributed, which means that the networks are characterized by homogeneity. However, many realistic networks exhibit inhomogeneity due to natural and man-made reasons. In this work, the capacity of inhomogeneous hybrid networks with directional antennas for the first time is studied. By setting different node distribution probabilities, the whole network can be devided into dense cells and sparse cells. On this basis, an inhomogeneous hybrid network model is proposed. The network can exhibit significant inhomogeneity due to the coexistence of two types of cells. Then, we derive the network capacity and maximize the capacity under different channel allocation schemes. Finally, how the network parameters influence the network capacity is analyzed. It is found that if there are plenty of base stations, the per-node throughput can achieve constant order, and if the beamwidth of directional antenna is small enough, the network capacity can scale.

  1. Hybrid Scenario Based Performance Analysis of DSDV and DSSR

    CERN Document Server

    Majumder, Koushik; 10.5121/ijcsit.2010.2305

    2010-01-01

    The area of mobile ad hoc networking has received considerable attention of the research community in recent years. These networks have gained immense popularity primarily due to their infrastructure-less mode of operation which makes them a suitable candidate for deployment in emergency scenarios like relief operation, battlefield etc., where either the pre-existing infrastructure is totally damaged or it is not possible to establish a new infrastructure quickly. However, MANETs are constrained due to the limited transmission range of the mobile nodes which reduces the total coverage area. Sometimes the infrastructure-less ad hoc network may be combined with a fixed network to form a hybrid network which can cover a wider area with the advantage of having less fixed infrastructure. In such a combined network, for transferring data, we need base stations which act as gateways between the wired and wireless domains. Due to the hybrid nature of these networks, routing is considered a challenging task. Several r...

  2. Coexistence analysis of diploid and triploid hybrid water frogs

    Science.gov (United States)

    Apri, M.; Suandi, D.; Soewono, E.

    2014-02-01

    A dynamical model for genotype distributions of all hybrid populations of Pelophylax esculentus in the absence of differential survival is studied here. Assuming that under natural condition the parental genotypes LL and RR do not survive into adult stage, the dynamic is then reduced into three-dimensional dynamical system of classes LR, LLR, LRR genotypes. Coexistence of diploid (LR) and triploid (LLR and LRR) genotypes is analyzed here.

  3. Delta-Complete Analysis for Bounded Reachability of Hybrid Systems

    Science.gov (United States)

    2014-07-16

    can occur in realistic hybrid sys- tems, such as polynomials, trigonometric functions , and solutions of Lipschitz-continuous ODEs. The goal of this...systems are Type 2 computable, such as polynomials, exponentiation, logarithm, trigonometric functions , and solution functions of Lipschitz-continuous...comes from the need of solving logic formulas over the real numbers with nonlinear functions , which is notoriously hard. Recently, we have defined the δ

  4. Hybrid Threat Center of Gravity Analysis: Cutting the Gordian Knot

    Science.gov (United States)

    2016-04-04

    observed “the response from Jerusalem was both quick and violent, surprising Hezbollah’s leadership and triggering a month-long conflict that, in...urban areas that caught the IDF completely by surprise . Peters notes three distinct advantages employed by Hezbollah in the development of its hybrid...Ukraine. These “green men” had no identifying marks or uniforms yet operated with amazing efficiency and tactical proficiency.2 No shots were fired

  5. The Gwaii Haanas PV hybrid system : analysis of system operation

    Energy Technology Data Exchange (ETDEWEB)

    Ross, M. [GPCo Inc., Varennes, PQ (Canada); Turcotte, D.; Sheriff, F. [Natural Resources Canada, Varennes, PQ (Canada). CANMET Energy Technology Centre

    2003-05-01

    The operation of the photovoltaic/battery/genset hybrid power system at the Gwaii Haanas National Park Reserve warden station in British Columbia has been monitored since July 2001 as part of the Canada Centre for Mineral and Energy Technology (CANMET) Energy Technology Centre-Varennes Photovoltaic Hybrid Power Systems Program. The data collected has been used to validate hybrid system simulation tools being developed under the sponsorship of the Program. The analyzed data, along with the simulation tools, provided insight into the operation of the Gwaii Haanas power system. It also assisted in identifying the strengths and weaknesses of the system. Data indicates that the system functions well and is appropriately dimensioned and configured. The modules are arranged in two sub-arrays, with modules connected in parallel, showing remarkable tolerance to shading of part of the array. Almost complete discharge of the batteries occurs during the winter, when the Park residence is unoccupied. During the summer, users should keep track of the battery state-of-charge. Some recommendations were made to prolong the battery life. 1 ref., 1 tab., 16 figs.

  6. Hybrid Psychology: The marriage of discourse analysis with neuroscience

    Directory of Open Access Journals (Sweden)

    Rom Harré

    2010-07-01

    Full Text Available As the 21st Century opened the controversial and unstable discipline of `academic psychology’ seemed to separating into two radically distinct and perhaps irreconcilable domains. Discursive psychology focused on the management of meaning in a world of norms while Neuropsychology focused on the investigation of brain and cognitive processes. These two domains can be reconciled in a hybrid science that brings them together into a synthesis more powerful than anything psychologists have achieved before. In this paper means Hybrid psychology depends on the intuition that while brains can be assimilated into the world of persons, people cannot be assimilated into the world of cell structures and molecular processes. The project of setting up a hybrid science, in which the symbol using capacities of human beings are brought into a unified scheme with the organic aspects of members of the species homo sapiens, demands the dissolution of the mind-body problem, somehow setting it aside as an illusion, based on a mistaken presupposition.

  7. HYBRID SULFUR PROCESS REFERENCE DESIGN AND COST ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    Gorensek, M.; Summers, W.; Boltrunis, C.; Lahoda, E.; Allen, D.; Greyvenstein, R.

    2009-05-12

    This report documents a detailed study to determine the expected efficiency and product costs for producing hydrogen via water-splitting using energy from an advanced nuclear reactor. It was determined that the overall efficiency from nuclear heat to hydrogen is high, and the cost of hydrogen is competitive under a high energy cost scenario. It would require over 40% more nuclear energy to generate an equivalent amount of hydrogen using conventional water-cooled nuclear reactors combined with water electrolysis compared to the proposed plant design described herein. There is a great deal of interest worldwide in reducing dependence on fossil fuels, while also minimizing the impact of the energy sector on global climate change. One potential opportunity to contribute to this effort is to replace the use of fossil fuels for hydrogen production by the use of water-splitting powered by nuclear energy. Hydrogen production is required for fertilizer (e.g. ammonia) production, oil refining, synfuels production, and other important industrial applications. It is typically produced by reacting natural gas, naphtha or coal with steam, which consumes significant amounts of energy and produces carbon dioxide as a byproduct. In the future, hydrogen could also be used as a transportation fuel, replacing petroleum. New processes are being developed that would permit hydrogen to be produced from water using only heat or a combination of heat and electricity produced by advanced, high temperature nuclear reactors. The U.S. Department of Energy (DOE) is developing these processes under a program known as the Nuclear Hydrogen Initiative (NHI). The Republic of South Africa (RSA) also is interested in developing advanced high temperature nuclear reactors and related chemical processes that could produce hydrogen fuel via water-splitting. This report focuses on the analysis of a nuclear hydrogen production system that combines the Pebble Bed Modular Reactor (PBMR), under development by

  8. Hybridization kinetics analysis of an oligonucleotide microarray for microRNA detection

    Institute of Scientific and Technical Information of China (English)

    Botao Zhao; Shuo Ding; Wei Li; Youxin Jin

    2011-01-01

    MicroRNA (miRNA) microarrays have been successfully used for profiling miRNA expression in many physiological processes such as development, differentiation, oncogenesis,and other disease processes. Detecting miRNA by miRNA microarray is actually based on nucleic acid hybridization between target molecules and their corresponding complementary probes. Due to the small size and high degree of similarity among miRNA sequences, the hybridization condition must be carefully optimized to get specific and reliable signals. Previously, we reported a microarray platform to detect miRNA expression. In this study, we evaluated the sensitivity and specificity of our microarray platform. After systematic analysis, we determined an optimized hybridization condition with high sensitivity and specificity for miRNA detection. Our results would be helpful for other hybridization-based miRNA detection methods, such as northern blot and nuclease protection assay.

  9. EVALUATION OF HYBRIDIZATION BETWEEN PANGASIUS DJAMBAL BLEEKER 1846 AND PANGASIANODON HYPOPHTHALMUS (SAUVAGE 1878: BIOMETRIC CHARACTERIZATION AND GROWTH ANALYSIS

    Directory of Open Access Journals (Sweden)

    Rudhy Gustiano

    2007-06-01

    Full Text Available Possible use of pangasiid hybrids in aquaculture might generate potential impacts on wild populations. Therefore, rapid identification tools in the field such as growth rate are urgently needed. This study examines morphological characters and growth performance of P. djambal and P. hypophthalmus and their reciprocal hybrids. A detailed morphological study analysed 32 morphometric measurements and 5 meristic counts on hybrids of Pangasius djambal and P. hypophthalmus. Morphometric analysis and meristic counts showed that the reciprocal hybrids have intermediate characters except for gill rakers number which were lower than that of parental species. In general, the hybrids have tendency to be like P. hypophthalmus rather than P. djambal. The only typical character P. djambal appearing in hybrids is teeth shape, both vomerine and palatine. It was shown that the true hybrids have seven pelvic fin rays. Eight months of growth comparison in earthen ponds showed that the hybrids have a better performance for specific growth rate than the parental stock.

  10. Comparative genomic hybridization analysis of benign and invasive male breast neoplasms

    DEFF Research Database (Denmark)

    Ojopi, Elida Paula Benquique; Cavalli, Luciane Regina; Cavalieri, Luciane Mara Bogline

    2002-01-01

    Comparative genomic hybridization (CGH) analysis was performed for the identification of chromosomal imbalances in two benign gynecomastias and one malignant breast carcinoma derived from patients with male breast disease and compared with cytogenetic analysis in two of the three cases. CGH analy...

  11. Hybrid Vortex Method for the Aerodynamic Analysis of Wind Turbine

    Directory of Open Access Journals (Sweden)

    Hao Hu

    2015-01-01

    Full Text Available The hybrid vortex method, in which vortex panel method is combined with the viscous-vortex particle method (HPVP, was established to model the wind turbine aerodynamic and relevant numerical procedure program was developed to solve flow equations. The panel method was used to calculate the blade surface vortex sheets and the vortex particle method was employed to simulate the blade wake vortices. As a result of numerical calculations on the flow over a wind turbine, the HPVP method shows significant advantages in accuracy and less computation resource consuming. The validation of the aerodynamic parameters against Phase VI wind turbine experimental data is performed, which shows reasonable agreement.

  12. Using a Hybrid Cost-FMEA Analysis for Wind Turbine Reliability Analysis

    Directory of Open Access Journals (Sweden)

    Nacef Tazi

    2017-02-01

    Full Text Available Failure mode and effects analysis (FMEA has been proven to be an effective methodology to improve system design reliability. However, the standard approach reveals some weaknesses when applied to wind turbine systems. The conventional criticality assessment method has been criticized as having many limitations such as the weighting of severity and detection factors. In this paper, we aim to overcome these drawbacks and develop a hybrid cost-FMEA by integrating cost factors to assess the criticality, these costs vary from replacement costs to expected failure costs. Then, a quantitative comparative study is carried out to point out average failure rate, main cause of failure, expected failure costs and failure detection techniques. A special reliability analysis of gearbox and rotor-blades are presented.

  13. Power quality analysis of hybrid renewable energy system

    Directory of Open Access Journals (Sweden)

    Rinchin W. Mosobi

    2015-12-01

    Full Text Available An hybrid renewable energy sources consisting of solar photovoltaic, wind energy system, and a microhydro system is proposed in this paper. This system is suitable for supplying electricity to isolated locations or remote villages far from the grid supply. The solar photovoltaic system is modeled with two power converters, the first one being a DC-DC converter along with an maximum power point tracking to achieve a regulated DC output voltage and the second one being a DC-AC converter to obtain AC output. The wind energy system is modeled with a wind-turbine prime mover with varying wind speed and fixed pitch angle to drive an self excited induction generator (SEIG. Owing to inherent drooping characteristics of the SEIG, a closed loop turbine input system is incorporated. The microhydro system is modeled with a constant input power to drive an SEIG. The three different sources are integrated through an AC bus and the proposed hybrid system is supplied to R, R-L, and induction motor loads. A static compensator is proposed to improve the load voltage and current profiles; it also mitigates the harmonic contents of the voltage and current. The static synchronous compensator is realized by means of a three-phase IGBT-based current-controlled voltage source inverter with a self-supporting DC bus. The complete system is modeled and simulated using Matlab/Simulink. The simulation results obtained illustrate the feasibility of the proposed system and are found to be satisfactory.

  14. Analysis of a Hybrid Solar-Assisted Trigeneration System

    Directory of Open Access Journals (Sweden)

    Elisa Marrasso

    2016-09-01

    Full Text Available A hybrid solar-assisted trigeneration system is analyzed in this paper. The system is composed of a 20 m2 solar field of evacuated tube collectors, a natural gas fired micro combined heat and power system delivering 12.5 kW of thermal power, an absorption heat pump (AHP with a nominal cooling power of 17.6 kW, two storage tanks (hot and cold and an electric auxiliary heater (AH. The plant satisfies the energy demand of an office building located in Naples (Southern Italy. The electric energy of the cogenerator is used to meet the load and auxiliaries electric demand; the interactions with the grid are considered in cases of excess or over requests. This hybrid solution is interesting for buildings located in cities or historical centers with limited usable roof surface to install a conventional solar heating and cooling (SHC system able to achieve high solar fraction (SF. The results of dynamic simulation show that a tilt angle of 30° maximizes the SF of the system on annual basis achieving about 53.5%. The influence on the performance of proposed system of the hot water storage tank (HST characteristics (volume, insulation is also studied. It is highlighted that the SF improves when better insulated and bigger HSTs are considered. A maximum SF of about 58.2% is obtained with a 2000 L storage, whereas the lower thermal losses take place with a better insulated 1000 L tank.

  15. Power flow analysis for droop controlled LV hybrid AC-DC microgrids with virtual impedance

    DEFF Research Database (Denmark)

    Li, Chendan; Chaudhary, Sanjay; Vasquez, Juan Carlos

    2014-01-01

    The AC-DC hybrid microgrid is an effective form of utilizing different energy resources and the analysis of this system requires a proper power flow algorithm. This paper proposes a suitable power flow algorithm for LV hybrid AC-DC microgrid based on droop control and virtual impedance. Droop...... and virtual impedance concepts for AC network, DC network and interlinking converter are reviewed so as to model it in the power flow analysis. The validation of the algorithm is verified by comparing it with steady state results from detailed time domain simulation. The effectiveness of the proposed...

  16. Transcriptomic analysis of Crassostrea sikamea × Crassostrea angulata hybrids in response to low salinity stress

    Science.gov (United States)

    Yan, Lulu; Su, Jiaqi; Wang, Zhaoping; Yan, Xiwu; Yu, Ruihai; Ma, Peizhen; Li, Yangchun; Du, Junpeng

    2017-01-01

    Hybrid oysters often show heterosis in growth rate, weight, survival and adaptability to extremes of salinity. Oysters have also been used as model organisms to study the evolution of host-defense system. To gain comprehensive knowledge about various physiological processes in hybrid oysters under low salinity stress, we performed transcriptomic analysis of gill tissue of Crassostrea sikamea ♀ × Crassostrea angulata♂ hybrid using the deep-sequencing platform Illumina HiSeq. We exploited the high-throughput technique to delineate differentially expressed genes (DEGs) in oysters maintained in hypotonic conditions. A total of 199,391 high quality unigenes, with average length of 644 bp, were generated. Of these 35 and 31 genes showed up- and down-regulation, respectively. Functional categorization and pathway analysis of these DEGs revealed enrichment for immune mechanism, apoptosis, energy metabolism and osmoregulation under low salinity stress. The expression patterns of 41 DEGs in hybrids and their parental species were further analyzed by quantitative real-time PCR (qRT-PCR). This study will serve as a platform for subsequent gene expression analysis regarding environmental stress. Our findings will also provide valuable information about gene expression to better understand the immune mechanism, apoptosis, energy metabolism and osmoregulation in hybrid oysters under low salinity stress. PMID:28182701

  17. Yield stability and adaptability of maize hybrids based on GGE biplot analysis characteristics

    Directory of Open Access Journals (Sweden)

    Marcio Balestre

    2009-01-01

    Full Text Available The objective of this study was to evaluate stability and adaptability of the grain yield of commercial intervarietalmaize hybrids by the GGE (Genotype and Genotype by Environment Interaction biplot and AMMI (Additive Main Effects andMultiplicative Interaction analyses. Two intervarietal hybrids (BIO 2 and BIO4 were evaluated together with single, doubleand three-way cross hybrids. The performance of the intervarietal hybrid BIO 4 was superior to all double and three-waycross hybrids and outmatched the single-cross hybrids by 43%. In terms of stability, BIO 2 was more stable than BIO4, whichis desirable, but biological stability, which is not necessarily desirable, was also observed, since the yield was below theenvironmental mean. The graphical GGE biplot analysis was superior to the AMMI1 since a greater portion of the sum ofsquares of GE and G+GE was captured and the predictive accuracy was higher. On the other hand, the AMMI2 graphoutperformed the GGE biplot in predictive accuracy and explanation of G + GE and GE, although the difference in accuracywas smaller than between GGE2 and AMMI1.

  18. Sample preparation and in situ hybridization techniques for automated molecular cytogenetic analysis of white blood cells

    Energy Technology Data Exchange (ETDEWEB)

    Rijke, F.M. van de; Vrolijk, H.; Sloos, W. [Leiden Univ. (Netherlands)] [and others

    1996-06-01

    With the advent in situ hybridization techniques for the analysis of chromosome copy number or structure in interphase cells, the diagnostic and prognostic potential of cytogenetics has been augmented considerably. In theory, the strategies for detection of cytogenetically aberrant cells by in situ hybridization are simple and straightforward. In practice, however, they are fallible, because false classification of hybridization spot number or patterns occurs. When a decision has to be made on molecular cytogenetic normalcy or abnormalcy of a cell sample, the problem of false classification becomes particularly prominent if the fraction of aberrant cells is relatively small. In such mosaic situations, often > 200 cells have to be evaluated to reach a statistical sound figure. The manual enumeration of in situ hybridization spots in many cells in many patient samples is tedious. Assistance in the evaluation process by automation of microscope functions and image analysis techniques is, therefore, strongly indicated. Next to research and development of microscope hardware, camera technology, and image analysis, the optimization of the specimen for the (semi)automated microscopic analysis is essential, since factors such as cell density, thickness, and overlap have dramatic influences on the speed and complexity of the analysis process. Here we describe experiments that have led to a protocol for blood cell specimen that results in microscope preparations that are well suited for automated molecular cytogenetic analysis. 13 refs., 4 figs., 1 tab.

  19. Evaluating the Fin-ray Trajectory Tracking of Bio-inspired Robotic Undulating Fins via an Experimental-numerical Approach

    Directory of Open Access Journals (Sweden)

    Xiaojia Xiang

    2014-07-01

    Full Text Available In the past decade, biomimetic undulating fin propulsion has been one of the main topics considered by scientists and researchers in the field of robotic fish. This technology is inspired by the biological wave-like propulsion of ribbon-finned fish. The swimming modes have aquatic application potentials with greater manoeuvrability, less detectable noise or wake and better efficiency at low speeds. The present work concentrates on the evaluation of fin-ray trajectory tracking of biorobotic undulating fins at the levels of kinematics and hydrodynamics by using an experimental-numerical approach. Firstly, fin-ray tracking inconsistence between the desired and actual undulating trajectories is embodied with experimental data of the fin prototype. Next, the dynamics' nonlinearity is numerically and analytically unveiled by using the computational fluid dynamics (CFD method, from the viewpoint of vortex shedding and the hydro-effect. The evaluation of fin-ray tracking performance creates a good basis for control design to improve the fin-ray undulation of prototypes.

  20. Modeling, analysis and control of fuel cell hybrid power systems

    Science.gov (United States)

    Suh, Kyung Won

    Transient performance is a key characteristic of fuel cells, that is sometimes more critical than efficiency, due to the importance of accepting unpredictable electric loads. To fulfill the transient requirement in vehicle propulsion and portable fuel cell applications, a fuel cell stack is typically coupled with a battery through a DC/DC converter to form a hybrid power system. Although many power management strategies already exist, they all rely on low level controllers that realize the power split. In this dissertation we design controllers that realize various power split strategies by directly manipulating physical actuators (low level commands). We maintain the causality of the electric dynamics (voltage and current) and investigate how the electric architecture affects the hybridization level and the power management. We first establish the performance limitations associated with a stand-alone and power-autonomous fuel cell system that is not supplemented by an additional energy storage and powers all its auxiliary components by itself. Specifically, we examine the transient performance in fuel cell power delivery as it is limited by the air supplied by a compressor driven by the fuel cell itself. The performance limitations arise from the intrinsic coupling in the fluid and electrical domain between the compressor and the fuel cell stack. Feedforward and feedback control strategies are used to demonstrate these limitations analytically and with simulations. Experimental tests on a small commercial fuel cell auxiliary power unit (APU) confirm the dynamics and the identified limitations. The dynamics associated with the integration of a fuel cell system and a DC/DC converter is then investigated. Decentralized and fully centralized (using linear quadratic techniques) controllers are designed to regulate the power system voltage and to prevent fuel cell oxygen starvation. Regulating these two performance variables is a difficult task and requires a compromise

  1. Analysis of extensive air showers with the hybrid code SENECA

    CERN Document Server

    Ortiz, J A; Medina-Tanco, G; Ortiz, Jeferson A.; Souza, Vitor de; Medina-Tanco, Gustavo

    2005-01-01

    The ultrahigh energy tail of the cosmic ray spectrum has been explored with unprecedented detail. For this reason, new experiments are exerting a severe pressure on extensive air shower modeling. Detailed fast codes are in need in order to extract and understand the richness of information now available. In this sense we explore the potential of SENECA, an efficient hybrid tridimensional simulation code, as a valid practical alternative to full Monte Carlo simulations of extensive air showers generated by ultrahigh energy cosmic rays. We discuss the influence of this approach on the main longitudinal characteristics of proton, iron nucleus and gamma induced air showers for different hadronic interaction models. We also show the comparisons of our predictions with those of CORSIKA code.

  2. Analysis of extensive air showers with the hybrid code SENECA

    Science.gov (United States)

    Ortiz, Jeferson A.; de Souza, Vitor; Medina-Tanco, Gustavo

    The ultrahigh energy tail of the cosmic ray spectrum has been explored with unprecedented detail. For this reason, new experiments are exerting a severe pressure on extensive air shower modeling. Detailed fast codes are in need in order to extract and understand the richness of information now available. In this sense we explore the potential of SENECA, an efficient hybrid tridimensional simulation code, as a valid practical alternative to full Monte Carlo simulations of extensive air showers generated by ultrahigh energy cosmic rays. We discuss the influence of this approach on the main longitudinal characteristics of proton, iron nucleus and gamma induced air showers for different hadronic interaction models. We also show the comparisons of our predictions with those of CORSIKA code.

  3. A dynamical system analysis of hybrid metric-Palatini cosmologies

    CERN Document Server

    Carloni, Sante; Lobo, Francisco S N

    2015-01-01

    The so called $f(X)$ hybrid metric-Palatini gravity presents a unique viable generalisation of the $f(R)$ theories within the metric-affine formalism. Here the cosmology of the $f(X)$ theories is studied using the dynamical system approach. The method consists of formulating the propagation equation in terms of suitable (expansion-normalised) variables as an autonomous system. The fixed points of the system then represent exact cosmological solutions described by power-law or de Sitter expansion. The formalism is applied to two classes of $f(X)$ models, revealing both standard cosmological fixed points and new accelerating solutions that can be attractors in the phase space. In addition, the fixed point with vanishing expansion rate are considered with special care in order to characterise the stability of Einstein static spaces and bouncing solutions.

  4. Flexural analysis of palm fiber reinforced hybrid polymer matrix composite

    Science.gov (United States)

    Venkatachalam, G.; Gautham Shankar, A.; Raghav, Dasarath; Santhosh Kiran, R.; Mahesh, Bhargav; Kumar, Krishna

    2015-07-01

    Uncertainty in availability of fossil fuels in the future and global warming increased the need for more environment friendly materials. In this work, an attempt is made to fabricate a hybrid polymer matrix composite. The blend is a mixture of General Purpose Resin and Cashew Nut Shell Liquid, a natural resin extracted from cashew plant. Palm fiber, which has high strength, is used as reinforcement material. The fiber is treated with alkali (NaOH) solution to increase its strength and adhesiveness. Parametric study of flexure strength is carried out by varying alkali concentration, duration of alkali treatment and fiber volume. Taguchi L9 Orthogonal array is followed in the design of experiments procedure for simplification. With the help of ANOVA technique, regression equations are obtained which gives the level of influence of each parameter on the flexure strength of the composite.

  5. Hybrid Additive Manufacturing Technologies - An Analysis Regarding Potentials and Applications

    Science.gov (United States)

    Merklein, Marion; Junker, Daniel; Schaub, Adam; Neubauer, Franziska

    Imposing the trend of mass customization of lightweight construction in industry, conventional manufacturing processes like forming technology and chipping production are pushed to their limits for economical manufacturing. More flexible processes are needed which were developed by the additive manufacturing technology. This toolless production principle offers a high geometrical freedom and an optimized utilization of the used material. Thus load adjusted lightweight components can be produced in small lot sizes in an economical way. To compensate disadvantages like inadequate accuracy and surface roughness hybrid machines combining additive and subtractive manufacturing are developed. Within this paper the principles of mainly used additive manufacturing processes of metals and their possibility to be integrated into a hybrid production machine are summarized. It is pointed out that in particular the integration of deposition processes into a CNC milling center supposes high potential for manufacturing larger parts with high accuracy. Furthermore the combination of additive and subtractive manufacturing allows the production of ready to use products within one single machine. Additionally actual research for the integration of additive manufacturing processes into the production chain will be analyzed. For the long manufacturing time of additive production processes the combination with conventional manufacturing processes like sheet or bulk metal forming seems an effective solution. Especially large volumes can be produced by conventional processes. In an additional production step active elements can be applied by additive manufacturing. This principle is also investigated for tool production to reduce chipping of the high strength material used for forming tools. The aim is the addition of active elements onto a geometrical simple basis by using Laser Metal Deposition. That process allows the utilization of several powder materials during one process what

  6. Transcriptome Analysis Identifies Key Candidate Genes Mediating Purple Ovary Coloration in Asiatic Hybrid Lilies

    Science.gov (United States)

    Xu, Leifeng; Yang, Panpan; Yuan, Suxia; Feng, Yayan; Xu, Hua; Cao, Yuwei; Ming, Jun

    2016-01-01

    Lily tepals have a short lifespan. Once the tepals senesce, the ornamental value of the flower is lost. Some cultivars have attractive purple ovaries and fruits which greatly enhance the ornamental value of Asiatic hybrid lilies. However, little is known about the molecular mechanisms of anthocyanin biosynthesis in Asiatic hybrid lily ovaries. To investigate the transcriptional network that governs purple ovary coloration in Asiatic hybrid lilies, we obtained transcriptome data from green ovaries (S1) and purple ovaries (S2) of Asiatic “Tiny Padhye”. Comparative transcriptome analysis revealed 4228 differentially expressed genes. Differential expression analysis revealed that ten unigenes including four CHS genes, one CHI gene, one F3H gene, one F3′H gene, one DFR gene, one UFGT gene, and one 3RT gene were significantly up-regulated in purple ovaries. One MYB gene, LhMYB12-Lat, was identified as a key transcription factor determining the distribution of anthocyanins in Asiatic hybrid lily ovaries. Further qPCR results showed unigenes related to anthocyanin biosynthesis were highly expressed in purple ovaries of three purple-ovaried Asiatic hybrid lilies at stages 2 and 3, while they showed an extremely low level of expression in ovaries of three green-ovaried Asiatic hybrid lilies during all developmental stages. In addition, shading treatment significantly decreased pigment accumulation by suppressing the expression of several unigenes related to anthocyanin biosynthesis in ovaries of Asiatic “Tiny Padhye”. Lastly, a total of 15,048 Simple Sequence Repeats (SSRs) were identified in 13,710 sequences, and primer pairs for SSRs were designed. The results could further our understanding of the molecular mechanisms of anthocyanin biosynthesis in Asiatic hybrid lily ovaries. PMID:27879624

  7. Genetic analysis of X-linked hybrid sterility in the house mouse.

    Science.gov (United States)

    Storchová, Radka; Gregorová, Sona; Buckiová, Daniela; Kyselová, Vendula; Divina, Petr; Forejt, Jirí

    2004-07-01

    Hybrid sterility is a common postzygotic reproductive isolation mechanism that appears in the early stages of speciation of various organisms. Mus musculus musculus and Mus musculus domesticus represent two recently separated mouse subspecies particularly suitable for genetic studies of hybrid sterility. Here we show that the introgression of Chr X of M. m. musculus origin (PWD/Ph inbred strain, henceforth PWD) into the genetic background of the C57BL/6J (henceforth B6) inbred strain (predominantly of M. m. domesticus origin) causes male sterility. The X-linked hybrid sterility is associated with reduced testes weight, lower sperm count, and morphological abnormalities of sperm heads. The analysis of recombinant Chr Xs in sterile and fertile males as well as quantitative trait locus (QTL) analysis of several fertility parameters revealed an oligogenic nature of the X-linked hybrid sterility. The Hstx1 locus responsible for male sterility was mapped near DXMit119 in the central part of Chr X. To ensure full sterility, the PWD allele of Hstx1 has to be supported with the PWD allelic form of loci in at least one proximal and/or one distal region of Chr X. Mapping and cloning of Hstx1 and other genes responsible for sterility of B6-X PWD Y B6 males could help to elucidate the special role of Chr X in hybrid sterility and consequently in speciation.

  8. Energy performance analysis for a photovoltaic, diesel, battery hybrid power supply system

    CSIR Research Space (South Africa)

    Tazvinga, Henerica

    2010-03-01

    Full Text Available This paper looks at an energy performance analysis for a photovoltaic, diesel, and battery hybrid power supply system. The procedure starts by the identification of the hourly load requirements for a typical target consumer and the concept of load...

  9. Study and Analysis of Congestion Management in Hybrid Electric Market

    Directory of Open Access Journals (Sweden)

    Moayed Mohseni

    2013-01-01

    Full Text Available The congestion management system is a systematic approach, collaboratively developed and implemented throughout a metropolitan region that provides for the safe and effective management and operation of new and existing transportation facilities through the use of demand reduction and operational management strat­e­gies. In this paper we try to present some points which should be investigated in congestion management problems. We calculate different kinds of congestion problems which may be occurred in our network. Here, the hybrid model is used to solve problems in the electricity market to solve the congestion problem in the network and Benders techniques is used together with an optimal power flow (OPF. In fact, by using of Benders algorithm the problem is divided into two major and minor problems. Therefore, the major problem related to the economy sector and no network is included and the minor problem is to solve the network and examine the accuracy of the network. Benders algorithm has been tested on a standard network IEEE 24 bus and Matlab software is used to implement the algorithm.

  10. Thermoeconomic Analysis of Hybrid Power Plant Concepts for Geothermal Combined Heat and Power Generation

    Directory of Open Access Journals (Sweden)

    Florian Heberle

    2014-07-01

    Full Text Available We present a thermo-economic analysis for a low-temperature Organic Rankine Cycle (ORC in a combined heat and power generation (CHP case. For the hybrid power plant, thermal energy input is provided by a geothermal resource coupled with the exhaust gases of a biogas engine. A comparison to alternative geothermal CHP concepts is performed by considering variable parameters like ORC working fluid, supply temperature of the heating network or geothermal water temperature. Second law efficiency as well as economic parameters show that hybrid power plants are more efficient compared to conventional CHP concepts or separate use of the energy sources.

  11. Performance Analysis of Hybrid PV/Diesel Energy System in Western Region of Saudi Arabia

    OpenAIRE

    Makbul A. M. Ramli; Ayong Hiendro; H. R. E. H. Bouchekara

    2014-01-01

    The potential implementation of hybrid photovoltaic (PV)/diesel energy system in western region of Saudi Arabia is analyzed in this paper. The solar radiation intensity considered in this study is in the range of 4.15–7.17 kWh/m2/day. The HOMER software is used to perform the technical and economical analysis of the system. Three different system configurations, namely, stand-alone diesel system, and hybrid PV/diesel system with and without battery storage element, will be evaluated and discu...

  12. Design tradeoff studies and sensitivity analysis, appendices B1 - B4. [hybrid electric vehicles

    Science.gov (United States)

    1979-01-01

    Documentation is presented for a program which separately computes fuel and energy consumption for the two modes of operation of a hybrid electric vehicle. The distribution of daily travel is specified as input data as well as the weights which the component driving cycles are given in each of the composite cycles. The possibility of weight reduction through the substitution of various materials is considered as well as the market potential for hybrid vehicles. Data relating to battery compartment weight distribution and vehicle handling analysis is tabulated.

  13. Analysis of the Fuel Efficiency of a Hybrid Electric Drive with an Electric Power Splitter

    Directory of Open Access Journals (Sweden)

    D. Čundev

    2008-01-01

    Full Text Available This paper presents the results of an analysis of the fuel efficiency of a hybrid electric car drive, with an electric power splitter based on a double rotor synchronous permanent magnet generator. The results have been obtained through a precisely determined mathematical model and by simulating the characteristics of all essential values for the entire drive. This work is related to the experimental working stand for electric and hybrid car drive research, which has been developed at the Faculty of Electrical Engineering (FEE at CTU in Prague. 

  14. Analysis of a model of fuel cell - gas turbine hybrid power system for enhanced energy efficiency

    Science.gov (United States)

    Calay, Rajnish K.; Mustafa, Mohamad Y.; Virk, Mohammad S.; Mustafa, Mahmoud F.

    2012-11-01

    A simple mathematical model to evaluate the performance of FC-GT hybrid system is presented in this paper. The model is used to analyse the influence of various parameters on the performance of a typical hybrid system, where excess heat rejected from the solid-oxide fuel cell stack is utilised to generate additional power through a gas turbine system and to provide heat energy for space heating. The model is based on thermodynamic analysis of various components of the plant and can be adapted for various configurations of the plant components. Because there are many parameters defining the efficiency and work output of the hybrid system, the technique is based on mathematical and graphical optimisation of various parameters; to obtain the maximum efficiency for a given plant configuration.

  15. Multiscale tomographic analysis of polymer-nanoparticle hybrid materials for solar cells

    Science.gov (United States)

    Lopez-Haro, Miguel; Jiu, Tonggang; Bayle-Guillemaud, Pascale; Jouneau, Pierre-Henri; Chandezon, Frédéric

    2013-10-01

    The present work focuses on the study of the three-dimensional (3D) morphology of polymer and nanoparticle hybrid nanocomposites used as active layers in solution-processed solar cells. The hybrid consists of blends of regioregular poly(3-alkylthiophene) and CdSe nanorods. Electron tomography (ET) analysis performed in high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) allows resolving single nanorods in the hybrid blend. These results are compared with those obtained using focused ion beam coupled with scanning electron microscopy (FIB-SEM), operated in a so-called 3D ``slice-and-view'' mode. This technique allows 3D information to be obtained on a whole device stack (hybrid active layers plus electrodes and the substrate) for significantly larger surface areas than with ET (~10 vs. ~0.1 μm2). The combination of ET and 3D FIB ``slice-and-view'' reconstructions provides complementary and coherent information on the 3D morphology of the hybrid systems at different length scales. Phase separation between the nanoparticles and the polymer is investigated by a quantitative analysis of the reconstructed volumes and is related to the performances of the hybrid devices.The present work focuses on the study of the three-dimensional (3D) morphology of polymer and nanoparticle hybrid nanocomposites used as active layers in solution-processed solar cells. The hybrid consists of blends of regioregular poly(3-alkylthiophene) and CdSe nanorods. Electron tomography (ET) analysis performed in high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) allows resolving single nanorods in the hybrid blend. These results are compared with those obtained using focused ion beam coupled with scanning electron microscopy (FIB-SEM), operated in a so-called 3D ``slice-and-view'' mode. This technique allows 3D information to be obtained on a whole device stack (hybrid active layers plus electrodes and the substrate) for

  16. Analysis of composition and microstructural uniformity of hybrid glass/carbon fibre composites

    DEFF Research Database (Denmark)

    Beauson, Justine; Markussen, Christen Malte; Madsen, Bo

    2013-01-01

    In hybrid fibre composites, the intermixing of the two types of fibres imposes challenges to obtain materials with a well-defined and uniform microstructure. In the present paper, the composition and the microstructural uniformity of hybrid glass/carbon fibre composites mixed at the fibre bundle...... fibre volume fractions are determined using volumetric calculations. A model is presented to predict the interrelation of volume fractions in hybrid fibre composites. The microstructural uniformity of the composites is analysed by the determined variation in composite volume fractions. Two analytical...... level are investigated. The different levels of compositions in the composites are defined and experimentally determined. The composite volume fractions are determined using an image analysis based procedure. The global fibre volume fractions are determined using a gravimetrical based method. The local...

  17. Flexural, Impact Properties and Sem Analysis of Bamboo and Glass Fiber Reinforced Polyester Hybrid Composites

    Directory of Open Access Journals (Sweden)

    Raghavendra Rao. H

    2014-08-01

    Full Text Available The Flexural, Impact properties and Scanning electron microscope analysis of Bamboo/glass fibers Reinforced polyester Hybrid composites were studied. The effect of alkali treatment of the bamboo fibers on these properties was also studied. It was observed that the Flexural, impact properties of the hybrid composite increase with glass fiber content. These properties found to be higher when alkali treated bamboo fibers were used in the hybrid composites. The elimination of amorphous hemi-cellulose with alkali treated leading to higher crystallinity of the bamboo fibers with alkali treatment may be responsible for these observations. The author investigated the interfacial bonding between Glass/Bamboo reinforced polyester composites. The effect of alkali treatment on the bonding between Glass/Bamboo composites was also studied.

  18. Combined analysis of cervical smears. Cytopathology, image cytometry and in situ hybridization.

    Science.gov (United States)

    Multhaupt, H; Bruder, E; Elit, L; Rothblat, I; Warhol, M

    1993-01-01

    This study was an attempt to correlate the Bethesda System of Papanicolaou smear classification with DNA content by image analysis and the presence of human papillomavirus (HPV) as determined by in situ hybridization. DNA histograms were classified as normal diploid, diploid proliferative, polyploid and aneuploid. HPV in situ hybridization was performed with a cocktail of probes specific to HPV types 6, 11, 16 and 18. There was a good correlation between normal cytology and normal DNA histograms. Cytologically normal smears with bacterial or fungal infections showed a high proliferation index. HPV infection correlated with DNA polyploidy but was seen in 15 of 29 smears classified as cytologically normal. Morphologically abnormal Papanicolaou smears correlated with aneuploid DNA content. Smears classified as intraepithelial neoplasia correlated with aneuploid DNA content in all 12 cases. Four of five cases cytologically suspicious for HPV infection had HPV by in situ hybridization.

  19. Analysis of the Hybrid Power System for High-Altitude Unmanned Aircraft

    Directory of Open Access Journals (Sweden)

    Kangwen Sun

    2015-01-01

    Full Text Available The application of single solar array on high-altitude unmanned aircraft will waste energy because of its low conversion efficiency. Furthermore, since its energy utilization is limited, the surface temperature of solar array will rise to 70°C due to the waste solar energy, thus reducing the electrical performance of the solar array. In order to reuse the energy converted into heat by solar array, a hybrid power system is presented in this paper. In the hybrid power system, a new electricity-generating method is adopted to spread the photovoltaic cell on the wing surface and arrange photothermal power in the wing box section. Because the temperature on the back of photovoltaic cell is high, it can be used as the high-temperature heat source. The lower wing surface can be a low-temperature cold source. A high-altitude unmanned aircraft was used to analyze the performances of pure solar-powered aircraft and hybrid powered aircraft. The analysis result showed that the hybrid system could reduce the area of wing by 19% and that high-altitude unmanned aircraft with a 35 m or less wingspan could raise the utilization rate of solar energy per unit area after adopting the hybrid power system.

  20. A hybrid approach to device integration on a genetic analysis platform

    Science.gov (United States)

    Brennan, Des; Jary, Dorothee; Kurg, Ants; Berik, Evgeny; Justice, John; Aherne, Margaret; Macek, Milan; Galvin, Paul

    2012-10-01

    Point-of-care (POC) systems require significant component integration to implement biochemical protocols associated with molecular diagnostic assays. Hybrid platforms where discrete components are combined in a single platform are a suitable approach to integration, where combining multiple device fabrication steps on a single substrate is not possible due to incompatible or costly fabrication steps. We integrate three devices each with a specific system functionality: (i) a silicon electro-wetting-on-dielectric (EWOD) device to move and mix sample and reagent droplets in an oil phase, (ii) a polymer microfluidic chip containing channels and reservoirs and (iii) an aqueous phase glass microarray for fluorescence microarray hybridization detection. The EWOD device offers the possibility of fully integrating on-chip sample preparation using nanolitre sample and reagent volumes. A key challenge is sample transfer from the oil phase EWOD device to the aqueous phase microarray for hybridization detection. The EWOD device, waveguide performance and functionality are maintained during the integration process. An on-chip biochemical protocol for arrayed primer extension (APEX) was implemented for single nucleotide polymorphism (SNiP) analysis. The prepared sample is aspirated from the EWOD oil phase to the aqueous phase microarray for hybridization. A bench-top instrumentation system was also developed around the integrated platform to drive the EWOD electrodes, implement APEX sample heating and image the microarray after hybridization.

  1. EVALUATION OF HYBRIDIZATION BETWEEN PANGASIUS DJAMBAL BLEEKER 1846 AND PANGASIANODON HYPOPHTHALMUS (SAUVAGE 1878): BIOMETRIC CHARACTERIZATION AND GROWTH ANALYSIS

    OpenAIRE

    Rudhy Gustiano; Anang Hari Kristanto

    2007-01-01

    Possible use of pangasiid hybrids in aquaculture might generate potential impacts on wild populations. Therefore, rapid identification tools in the field such as growth rate are urgently needed. This study examines morphological characters and growth performance of P. djambal and P. hypophthalmus and their reciprocal hybrids. A detailed morphological study analysed 32 morphometric measurements and 5 meristic counts on hybrids of Pangasius djambal and P. hypophthalmus. Morphometric analysis an...

  2. Hybrid molecular dynamics simulation for plasma induced damage analysis

    Science.gov (United States)

    Matsukuma, Masaaki

    2016-09-01

    In order to enable further device size reduction (also known as Moore's law) and improved power performance, the semiconductor industry is introducing new materials and device structures into the semiconductor fabrication process. Materials now include III-V compounds, germanium, cobalt, ruthenium, hafnium, and others. The device structure in both memory and logic has been evolving from planar to three dimensional (3D). One such device is the FinFET, where the transistor gate is a vertical fin made either of silicon, silicon-germanium or germanium. These changes have brought renewed interests in the structural damages caused by energetic ion bombardment of the fin sidewalls which are exposed to the ion flux from the plasma during the fin-strip off step. Better control of the physical damage of the 3D devices requires a better understanding of the damage formation mechanisms on such new materials and structures. In this study, the damage formation processes by ion bombardment have been simulated for Si and Ge substrate by Quantum Mechanics/Molecular Mechanics (QM/MM) hybrid simulations and compared to the results from the classical molecular dynamics (MD) simulations. In our QM/MM simulations, the highly reactive region in which the structural damage is created is simulated with the Density Functional based Tight Binding (DFTB) method and the region remote from the primary region is simulated using classical MD with the Stillinger-Weber and Moliere potentials. The learn on the fly method is also used to reduce the computational load. Hence our QM/MM simulation is much faster than the full QC-MD simulations and the original QM/MM simulations. The amorphous layers profile simulated with QM/MM have obvious differences in their thickness for silicon and germanium substrate. The profile of damaged structure in the germanium substrate is characterized by a deeper tail then in silicon. These traits are also observed in the results from the mass selected ion beam

  3. The strength of the hybrid braking calipers analysis

    Institute of Scientific and Technical Information of China (English)

    Li Weitao; Yu Haiqing; Jiang Xiaoyan

    2015-01-01

    The braking system is an important part to ensure the safety of the vehicle, so the strength analysis is essential to the brake caliper. In this article, the forces will be mixed in the caliper brake systems theoretical analysis, and based on the actual working conditions established calipers ABAQUS finite element model to simulate calipers provide a theoretical basis for the structural design of the brake caliper.

  4. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  5. Chromosomal imbalances in nasopharyngeal carcinoma: a meta-analysis of comparative genomic hybridization results

    Directory of Open Access Journals (Sweden)

    Jin Ping

    2006-01-01

    Full Text Available Abstract Nasopharyngeal carcinoma (NPC is a highly prevalent disease in Southeast Asia and its prevalence is clearly affected by genetic background. Various theories have been suggested for its high incidence in this geographical region but to these days no conclusive explanation has been identified. Chromosomal imbalances identifiable through comparative genomic hybridization may shed some light on common genetic alterations that may be of relevance to the onset and progression of NPC. Review of the literature, however, reveals contradictory results among reported findings possibly related to factors associated with patient selection, stage of disease, differences in methodological details etc. To increase the power of the analysis and attempt to identify commonalities among the reported findings, we performed a meta-analysis of results described in NPC tissues based on chromosomal comparative genomic hybridization (CGH. This meta-analysis revealed consistent patters in chromosomal abnormalities that appeared to cluster in specific "hot spots" along the genome following a stage-dependent progression.

  6. ANALYSIS OF ASSEMBLY SUITABILITY OF THE HYBRID NODE BASED ON WELD DISTORTION PREDICTION MODELS

    Directory of Open Access Journals (Sweden)

    Tomasz Urbański

    2015-08-01

    Full Text Available The article presents an analysis of assembly suitability of the innovative hybrid node. Weld distortions are a factor that affects significantly the quality of a structure during its pre-fabrication stage, thus increasing manufacturing costs . For the purposes of this analysis, such distortion forms were chosen that are the highest-ranking ones in the technological hierarchy. The analysis was performed taking advantage of significant parameters in order to demonstrate the possibilities of using mathematical models determined on the basis of a designed experiment to modify the construction technology as early as during the stage of the hybrid node’s manufacture. It was shown that using the above-mentioned theoretical models a technological assessment of the structural component can be performed by selecting such system of parameters that will produce distortions at a level acceptable from the point of view of further assembly suitability.

  7. New class of hybrid EoS and Bayesian M - R data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez-Castillo, D. [JINR Dubna, Bogoliubov Laboratory of Theoretical Physics, Dubna (Russian Federation); Ayriyan, A.; Grigorian, H. [JINR Dubna, Laboratory of Information Technologies, Dubna (Russian Federation); Benic, S. [University of Zagreb, Department of Physics, Zagreb (Croatia); Blaschke, D. [JINR Dubna, Bogoliubov Laboratory of Theoretical Physics, Dubna (Russian Federation); National Research Nuclear University (MEPhI), Moscow (Russian Federation); Typel, S. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany)

    2016-03-15

    We explore systematically a new class of two-phase equations of state (EoS) for hybrid stars that is characterized by three main features: (1) stiffening of the nuclear EoS at supersaturation densities due to quark exchange effects (Pauli blocking) between hadrons, modelled by an excluded volume correction; (2) stiffening of the quark matter EoS at high densities due to multiquark interactions; and (3) possibility for a strong first-order phase transition with an early onset and large density jump. The third feature results from a Maxwell construction for the possible transition from the nuclear to a quark matter phase and its properties depend on the two parameters used for (1) and (2), respectively. Varying these two parameters, one obtains a class of hybrid EoS that yields solutions of the Tolman-Oppenheimer-Volkoff (TOV) equations for sequences of hadronic and hybrid stars in the mass-radius diagram which cover the full range of patterns according to the Alford-Han-Prakash classification following which a hybrid star branch can be either absent, connected or disconnected with the hadronic one. The latter case often includes a tiny connected branch. The disconnected hybrid star branch, also called ''third family'', corresponds to high-mass twin stars characterized by the same gravitational mass but different radii. We perform a Bayesian analysis and demonstrate that the observation of such a pair of high-mass twin stars would have a sufficient discriminating power to favor hybrid EoS with a strong first-order phase transition over alternative EoS. (orig.)

  8. Reconstruction and analysis of hybrid composite shells using meshless methods

    Science.gov (United States)

    Bernardo, G. M. S.; Loja, M. A. R.

    2017-02-01

    The importance of focusing on the research of viable models to predict the behaviour of structures which may possess in some cases complex geometries is an issue that is growing in different scientific areas, ranging from the civil and mechanical engineering to the architecture or biomedical devices fields. In these cases, the research effort to find an efficient approach to fit laser scanning point clouds, to the desired surface, has been increasing, leading to the possibility of modelling as-built/as-is structures and components' features. However, combining the task of surface reconstruction and the implementation of a structural analysis model is not a trivial task. Although there are works focusing those different phases in separate, there is still an effective need to find approaches able to interconnect them in an efficient way. Therefore, achieving a representative geometric model able to be subsequently submitted to a structural analysis in a similar based platform is a fundamental step to establish an effective expeditious processing workflow. With the present work, one presents an integrated methodology based on the use of meshless approaches, to reconstruct shells described by points' clouds, and to subsequently predict their static behaviour. These methods are highly appropriate on dealing with unstructured points clouds, as they do not need to have any specific spatial or geometric requirement when implemented, depending only on the distance between the points. Details on the formulation, and a set of illustrative examples focusing the reconstruction of cylindrical and double-curvature shells, and its further analysis, are presented.

  9. Reconstruction and analysis of hybrid composite shells using meshless methods

    Science.gov (United States)

    Bernardo, G. M. S.; Loja, M. A. R.

    2017-06-01

    The importance of focusing on the research of viable models to predict the behaviour of structures which may possess in some cases complex geometries is an issue that is growing in different scientific areas, ranging from the civil and mechanical engineering to the architecture or biomedical devices fields. In these cases, the research effort to find an efficient approach to fit laser scanning point clouds, to the desired surface, has been increasing, leading to the possibility of modelling as-built/as-is structures and components' features. However, combining the task of surface reconstruction and the implementation of a structural analysis model is not a trivial task. Although there are works focusing those different phases in separate, there is still an effective need to find approaches able to interconnect them in an efficient way. Therefore, achieving a representative geometric model able to be subsequently submitted to a structural analysis in a similar based platform is a fundamental step to establish an effective expeditious processing workflow. With the present work, one presents an integrated methodology based on the use of meshless approaches, to reconstruct shells described by points' clouds, and to subsequently predict their static behaviour. These methods are highly appropriate on dealing with unstructured points clouds, as they do not need to have any specific spatial or geometric requirement when implemented, depending only on the distance between the points. Details on the formulation, and a set of illustrative examples focusing the reconstruction of cylindrical and double-curvature shells, and its further analysis, are presented.

  10. Rapid discrimination between four seagrass species using hybrid analysis.

    Science.gov (United States)

    Osathanunkul, M; Madesis, P; Ounjai, S; Suwannapoom, C; Jampeetong, A

    2015-04-27

    Biological species are traditionally identified based on their morphological features and the correct identification of species is critical in biological studies. However, some plant types, such as seagrass, are taxonomically problematic and difficult to identify. Furthermore, closely related seagrass species, such as Halophila spp, form a taxonomically unresolved complex. Although some seagrass taxa are easy to recognize, most species are difficult to identify without skilled taxonomic or molecular techniques. Barcoding coupled with High Resolution Melting analysis (BAR-HRM) offers a potentially reliable, rapid, and cost-effective method to confirm species. Here, DNA information of two chloroplast loci was used in combination with HRM analysis to discriminate four species of seagrass collected off the southern coast of Thailand. A distinct melting curve presenting one inflection point was generated for each species using rbcL primers. While the melting profiles of Cymodocea rotundata and Cymodocea serrulata were not statistically different, analysis of the normalized HRM curves produced with the rpoC primers allowed for their discrimination. The Bar-HRM technique showed promise in discriminating seagrass species and with further adaptations and improvements, could make for an effective and power tool for confirming seagrass species.

  11. A Hybrid Latent Class Analysis Modeling Approach to Analyze Urban Expressway Crash Risk.

    Science.gov (United States)

    Yu, Rongjie; Wang, Xuesong; Abdel-Aty, Mohamed

    2017-02-07

    Crash risk analysis is rising as a hot research topic as it could reveal the relationships between traffic flow characteristics and crash occurrence risk, which is beneficial to understand crash mechanisms which would further refine the design of Active Traffic Management System (ATMS). However, the majority of the current crash risk analysis studies have ignored the impact of geometric characteristics on crash risk estimation while recent studies proved that crash occurrence risk was affected by the various alignment features. In this study, a hybrid Latent Class Analysis (LCA) modeling approach was proposed to account for the heterogeneous effects of geometric characteristics. Crashes were first segmented into homogenous subgroups, where the optimal number of latent classes was identified based on bootstrap likelihood ratio tests. Then, separate crash risk analysis models were developed using Bayesian random parameter logistic regression technique; data from Shanghai urban expressway system were employed to conduct the empirical study. Different crash risk contributing factors were unveiled by the hybrid LCA approach and better model goodness-of-fit was obtained while comparing to an overall total crash model. Finally, benefits of the proposed hybrid LCA approach were discussed.

  12. Performance analysis on a hybrid air-conditioning system of a green building

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Q.; Wang, R.Z.; Dai, Y.J.; Zhai, X.Q. [Shanghai Jiao Tong University (China). School of Mechanical Engineering

    2006-05-15

    This paper presents the performance analysis on a hybrid air-conditioning system according to the hybrid building energy system of the green building demonstration project in Shanghai, in which a 150 m{sup 2} solar collector is used to power two 10 kW adsorption chillers, a vapor compression heat pump is used to cool air in the evaporating end while the condensing heating at about 80{sup o}C is fully used to regenerate a liquid desiccant dehumidification system. In the hybrid system, the sensible cooling to the air is treated mainly by solar adsorption cooling and vapor compression cooling, whereas the latent heat is treated by the liquid desiccant dehumidification system with regeneration from the condensing heat of the heat pump. The results show that the performance of this system is 44.5% higher than conventional vapor compression system at a latent load of 30% and this improving can be achieved by 73.8% at a 42% latent load. The optimal ratio of adsorption refrigerating power to total cooling load for this kind of hybrid systems is also studied in this paper. (author)

  13. A hybrid analysis method for linear dynamic soil-structure interaction in time and frequency domain

    Institute of Scientific and Technical Information of China (English)

    丁海平; 廖振鹏

    2001-01-01

    A hybrid analysis method in time and frequency domains for linear soil-structure interaction is presented. First, the time domain solution of the system with Rayleigh damping excited by a short time impulse is obtained by the decoupling numerical simulation technique of near-field wave motion. Then, the corresponding frequency domain solution can be got by Fourier transform. According to the relationship between damping value and dynamic re-sponse of a system, the solution of the system with complex damping can be got by Taylor expansion. The hybrid method makes the best of decoupling and explicit algorithm in time domain, and increases the calculation efficien-cy for linear soil-structure interaction analysis.

  14. Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization (FISH)

    DEFF Research Database (Denmark)

    Ronander, Elena; Bengtsson, Dominique C; Joergensen, Louise;

    2012-01-01

    and the consequence of differential binding on the clinical outcome of P. falciparum infections. Recently, the mutually exclusive transcription paradigm has been called into doubt by transcription assays based on individual P. falciparum transcript identification in single infected erythrocytic cells using RNA...... fluorescent in situ hybridization (FISH) analysis of var gene transcription by the parasite in individual nuclei of P. falciparum IE(1). Here, we present a detailed protocol for carrying out the RNA-FISH methodology for analysis of var gene transcription in single-nuclei of P. falciparum infected human...... erythrocytes. The method is based on the use of digoxigenin- and biotin- labeled antisense RNA probes using the TSA Plus Fluorescence Palette System(2) (Perkin Elmer), microscopic analyses and freshly selected P. falciparum IE. The in situ hybridization method can be used to monitor transcription...

  15. Finite Element Analysis of Adaptive-Stiffening and Shape-Control SMA Hybrid Composites

    Science.gov (United States)

    Gao, Xiujie; Burton, Deborah; Turner, Travis L.; Brinson, Catherine

    2005-01-01

    Shape memory alloy hybrid composites with adaptive-stiffening or morphing functions are simulated using finite element analysis. The composite structure is a laminated fiber-polymer composite beam with embedded SMA ribbons at various positions with respect to the neutral axis of the beam. Adaptive stiffening or morphing is activated via selective resistance heating of the SMA ribbons or uniform thermal loads on the beam. The thermomechanical behavior of these composites was simulated in ABAQUS using user-defined SMA elements. The examples demonstrate the usefulness of the methods for the design and simulation of SMA hybrid composites. Keywords: shape memory alloys, Nitinol, ABAQUS, finite element analysis, post-buckling control, shape control, deflection control, adaptive stiffening, morphing, constitutive modeling, user element

  16. Mobile 3D quality of experience evaluation: a hybrid data collection and analysis approach

    Science.gov (United States)

    Utriainen, Timo; Häyrynen, Jyrki; Jumisko-Pyykkö, Satu; Boev, Atanas; Gotchev, Atanas; Hannuksela, Miska M.

    2011-02-01

    The paper presents a hybrid approach to study the user's experienced quality of 3D visual content on mobile autostereoscopic displays. It combines extensive subjective tests with collection and objective analysis of eye-tracked data. 3D cues which are significant for mobiles are simulated in the generated 3D test content. The methodology for conducting subjective quality evaluation includes hybrid data-collection of quantitative quality preferences, qualitative impressions, and binocular eye-tracking. We present early results of the subjective tests along with eye movement reaction times, areas of interest and heatmaps obtained from raw eye-tracked data after statistical analysis. The study contributes to the question what is important to be visualized on portable auto-stereoscopic displays and how to maintain and visually enhance the quality of 3D content for such displays.

  17. A novel image compression-encryption hybrid algorithm based on the analysis sparse representation

    Science.gov (United States)

    Zhang, Ye; Xu, Biao; Zhou, Nanrun

    2017-06-01

    Recent advances on the compressive sensing theory were invoked for image compression-encryption based on the synthesis sparse model. In this paper we concentrate on an alternative sparse representation model, i.e., the analysis sparse model, to propose a novel image compression-encryption hybrid algorithm. The analysis sparse representation of the original image is obtained with an overcomplete fixed dictionary that the order of the dictionary atoms is scrambled, and the sparse representation can be considered as an encrypted version of the image. Moreover, the sparse representation is compressed to reduce its dimension and re-encrypted by the compressive sensing simultaneously. To enhance the security of the algorithm, a pixel-scrambling method is employed to re-encrypt the measurements of the compressive sensing. Various simulation results verify that the proposed image compression-encryption hybrid algorithm could provide a considerable compression performance with a good security.

  18. Hybrid modeling and empirical analysis of automobile supply chain network

    Science.gov (United States)

    Sun, Jun-yan; Tang, Jian-ming; Fu, Wei-ping; Wu, Bing-ying

    2017-05-01

    Based on the connection mechanism of nodes which automatically select upstream and downstream agents, a simulation model for dynamic evolutionary process of consumer-driven automobile supply chain is established by integrating ABM and discrete modeling in the GIS-based map. Firstly, the rationality is proved by analyzing the consistency of sales and changes in various agent parameters between the simulation model and a real automobile supply chain. Second, through complex network theory, hierarchical structures of the model and relationships of networks at different levels are analyzed to calculate various characteristic parameters such as mean distance, mean clustering coefficients, and degree distributions. By doing so, it verifies that the model is a typical scale-free network and small-world network. Finally, the motion law of this model is analyzed from the perspective of complex self-adaptive systems. The chaotic state of the simulation system is verified, which suggests that this system has typical nonlinear characteristics. This model not only macroscopically illustrates the dynamic evolution of complex networks of automobile supply chain but also microcosmically reflects the business process of each agent. Moreover, the model construction and simulation of the system by means of combining CAS theory and complex networks supplies a novel method for supply chain analysis, as well as theory bases and experience for supply chain analysis of auto companies.

  19. Cost Effectiveness Analysis of Quasi-Static Wireless Power Transfer for Plug-In Hybrid Electric Transit Buses: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Lijuan; Gonder, Jeff; Burton, Evan; Brooker, Aaron; Meintz, Andrew; Konan, Arnaud

    2015-11-11

    This study evaluates the costs and benefits associated with the use of a plug-in hybrid electric bus and determines the cost effectiveness relative to a conventional bus and a hybrid electric bus. A sensitivity sweep analysis was performed over a number of a different battery sizes, charging powers, and charging stations. The net present value was calculated for each vehicle design and provided the basis for the design evaluation. In all cases, given present day economic assumptions, the conventional bus achieved the lowest net present value while the optimal plug-in hybrid electric bus scenario reached lower lifetime costs than the hybrid electric bus. The study also performed parameter sensitivity analysis under low market potential assumptions and high market potential assumptions. The net present value of plug-in hybrid electric bus is close to that of conventional bus.

  20. Hybrid Finite Element Analysis of Free Edge Effect in Symmetric Composite Laminates

    Science.gov (United States)

    1983-06-01

    ANALYSIS OF FREE EDGE EFFECT IN L AUTHOR(S 61102F S.W. Lee237B J.J. Rhiu S.C. Won,, I ~ 7. PENOAMnG ORGANIZATION NAME(S) AND ADORES4 S) L. PERFORMING...ANALYSIS OF FREE EDGE EFFECT IN SYMMETRIC COMPOSITE LAMINATES S. W. Lee I 3. Phi S. C. Wong Department of Aerospace Engineering University of Maryland...collocation method. In this report, we present an efficient hybrid finite element method for analysis of interlaminar stress or free edge effect in

  1. Efficient Mooring Line Fatigue Analysis Using a Hybrid Method Time Domain Simulation Scheme

    DEFF Research Database (Denmark)

    Christiansen, Niels Hørbye; Voie, Per Erlend Torbergsen; Høgsberg, Jan Becker;

    2013-01-01

    Dynamic analyses of mooring line systems are computationally expensive. Over the last decades an extensive variety of methods to reduce this computational cost have been suggested. One method that has shown promising preliminary results is a hybrid method which combines finite element analysis...... and slow drift motion. The method is tested on a mooring line system of a floating offshore platform. After training a full fatigue analysis is carried out. The results show that the ANN with high precision provides top tension force histories two orders of magnitude faster than a full dynamic analysis...

  2. A microfluidic-based electrochemical biochip for label-free DNA hybridization analysis.

    Science.gov (United States)

    Ben-Yoav, Hadar; Dykstra, Peter H; Gordonov, Tanya; Bentley, William E; Ghodssi, Reza

    2014-09-10

    Miniaturization of analytical benchtop procedures into the micro-scale provides significant advantages in regards to reaction time, cost, and integration of pre-processing steps. Utilizing these devices towards the analysis of DNA hybridization events is important because it offers a technology for real time assessment of biomarkers at the point-of-care for various diseases. However, when the device footprint decreases the dominance of various physical phenomena increases. These phenomena influence the fabrication precision and operation reliability of the device. Therefore, there is a great need to accurately fabricate and operate these devices in a reproducible manner in order to improve the overall performance. Here, we describe the protocols and the methods used for the fabrication and the operation of a microfluidic-based electrochemical biochip for accurate analysis of DNA hybridization events. The biochip is composed of two parts: a microfluidic chip with three parallel micro-channels made of polydimethylsiloxane (PDMS), and a 3 x 3 arrayed electrochemical micro-chip. The DNA hybridization events are detected using electrochemical impedance spectroscopy (EIS) analysis. The EIS analysis enables monitoring variations of the properties of the electrochemical system that are dominant at these length scales. With the ability to monitor changes of both charge transfer and diffusional resistance with the biosensor, we demonstrate the selectivity to complementary ssDNA targets, a calculated detection limit of 3.8 nM, and a 13% cross-reactivity with other non-complementary ssDNA following 20 min of incubation. This methodology can improve the performance of miniaturized devices by elucidating on the behavior of diffusion at the micro-scale regime and by enabling the study of DNA hybridization events.

  3. Thermoeconomic Analysis of Hybrid Power Plant Concepts for Geothermal Combined Heat and Power Generation

    OpenAIRE

    Florian Heberle; Dieter Brüggemann

    2014-01-01

    We present a thermo-economic analysis for a low-temperature Organic Rankine Cycle (ORC) in a combined heat and power generation (CHP) case. For the hybrid power plant, thermal energy input is provided by a geothermal resource coupled with the exhaust gases of a biogas engine. A comparison to alternative geothermal CHP concepts is performed by considering variable parameters like ORC working fluid, supply temperature of the heating network or geothermal water temperature. Second law efficiency...

  4. Appendage modal coordinate truncation criteria in hybrid coordinate dynamic analysis. [for spacecraft attitude control

    Science.gov (United States)

    Likins, P.; Ohkami, Y.; Wong, C.

    1976-01-01

    The paper examines the validity of the assumption that certain appendage-distributed (modal) coordinates can be truncated from a system model without unacceptable degradation of fidelity in hybrid coordinate dynamic analysis for attitude control of spacecraft with flexible appendages. Alternative truncation criteria are proposed and their interrelationships defined. Particular attention is given to truncation criteria based on eigenvalues, eigenvectors, and controllability and observability. No definitive resolution of the problem is advanced, and exhaustive study is required to obtain ultimate truncation criteria.

  5. Hybrid Origins of Citrus Varieties Inferred from DNA Marker Analysis of Nuclear and Organelle Genomes

    Science.gov (United States)

    Kitajima, Akira; Nonaka, Keisuke; Yoshioka, Terutaka; Ohta, Satoshi; Goto, Shingo; Toyoda, Atsushi; Fujiyama, Asao; Mochizuki, Takako; Nagasaki, Hideki; Kaminuma, Eli; Nakamura, Yasukazu

    2016-01-01

    Most indigenous citrus varieties are assumed to be natural hybrids, but their parentage has so far been determined in only a few cases because of their wide genetic diversity and the low transferability of DNA markers. Here we infer the parentage of indigenous citrus varieties using simple sequence repeat and indel markers developed from various citrus genome sequence resources. Parentage tests with 122 known hybrids using the selected DNA markers certify their transferability among those hybrids. Identity tests confirm that most variant strains are selected mutants, but we find four types of kunenbo (Citrus nobilis) and three types of tachibana (Citrus tachibana) for which we suggest different origins. Structure analysis with DNA markers that are in Hardy–Weinberg equilibrium deduce three basic taxa coinciding with the current understanding of citrus ancestors. Genotyping analysis of 101 indigenous citrus varieties with 123 selected DNA markers infers the parentages of 22 indigenous citrus varieties including Satsuma, Temple, and iyo, and single parents of 45 indigenous citrus varieties, including kunenbo, C. ichangensis, and Ichang lemon by allele-sharing and parentage tests. Genotyping analysis of chloroplast and mitochondrial genomes using 11 DNA markers classifies their cytoplasmic genotypes into 18 categories and deduces the combination of seed and pollen parents. Likelihood ratio analysis verifies the inferred parentages with significant scores. The reconstructed genealogy identifies 12 types of varieties consisting of Kishu, kunenbo, yuzu, koji, sour orange, dancy, kobeni mikan, sweet orange, tachibana, Cleopatra, willowleaf mandarin, and pummelo, which have played pivotal roles in the occurrence of these indigenous varieties. The inferred parentage of the indigenous varieties confirms their hybrid origins, as found by recent studies. PMID:27902727

  6. Hybrid Origins of Citrus Varieties Inferred from DNA Marker Analysis of Nuclear and Organelle Genomes.

    Science.gov (United States)

    Shimizu, Tokurou; Kitajima, Akira; Nonaka, Keisuke; Yoshioka, Terutaka; Ohta, Satoshi; Goto, Shingo; Toyoda, Atsushi; Fujiyama, Asao; Mochizuki, Takako; Nagasaki, Hideki; Kaminuma, Eli; Nakamura, Yasukazu

    2016-01-01

    Most indigenous citrus varieties are assumed to be natural hybrids, but their parentage has so far been determined in only a few cases because of their wide genetic diversity and the low transferability of DNA markers. Here we infer the parentage of indigenous citrus varieties using simple sequence repeat and indel markers developed from various citrus genome sequence resources. Parentage tests with 122 known hybrids using the selected DNA markers certify their transferability among those hybrids. Identity tests confirm that most variant strains are selected mutants, but we find four types of kunenbo (Citrus nobilis) and three types of tachibana (Citrus tachibana) for which we suggest different origins. Structure analysis with DNA markers that are in Hardy-Weinberg equilibrium deduce three basic taxa coinciding with the current understanding of citrus ancestors. Genotyping analysis of 101 indigenous citrus varieties with 123 selected DNA markers infers the parentages of 22 indigenous citrus varieties including Satsuma, Temple, and iyo, and single parents of 45 indigenous citrus varieties, including kunenbo, C. ichangensis, and Ichang lemon by allele-sharing and parentage tests. Genotyping analysis of chloroplast and mitochondrial genomes using 11 DNA markers classifies their cytoplasmic genotypes into 18 categories and deduces the combination of seed and pollen parents. Likelihood ratio analysis verifies the inferred parentages with significant scores. The reconstructed genealogy identifies 12 types of varieties consisting of Kishu, kunenbo, yuzu, koji, sour orange, dancy, kobeni mikan, sweet orange, tachibana, Cleopatra, willowleaf mandarin, and pummelo, which have played pivotal roles in the occurrence of these indigenous varieties. The inferred parentage of the indigenous varieties confirms their hybrid origins, as found by recent studies.

  7. Hybrid Powder - Single Crystal X-Ray Diffraction Instrument for Planetary Mineralogical Analysis of Unprepared Samples Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop a planetary exploration XRD/XRF instrument based on a hybrid diffraction approach that complements powder XRD analysis, similar to that of the...

  8. Performance Analysis of Hybrid PV/Diesel Energy System in Western Region of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Makbul A. M. Ramli

    2014-01-01

    Full Text Available The potential implementation of hybrid photovoltaic (PV/diesel energy system in western region of Saudi Arabia is analyzed in this paper. The solar radiation intensity considered in this study is in the range of 4.15–7.17 kWh/m2/day. The HOMER software is used to perform the technical and economical analysis of the system. Three different system configurations, namely, stand-alone diesel system, and hybrid PV/diesel system with and without battery storage element, will be evaluated and discussed. The analysis will be addressed to the impact of PV penetration and battery storage on energy production, cost of energy, number of operational hours of diesel generators, fuel savings, and reduction of carbon emission for the given configurations. The simulation results indicate that the energy cost of the hybrid PV/diesel/battery system with 15% PV penetration, battery storage of 186.96 MWh, and energy demand of 32,962 MWh/day is $0.117/kWh.

  9. Phenotypic Variability and Diversity Analysis of Bean Traits of Some Cocoa Hybrids in Nigeria

    Directory of Open Access Journals (Sweden)

    A.V. Oyedokun

    2011-03-01

    Full Text Available It is essential to understand the economic potential and superiority among cocoa hybrids. Therefore, the present study aims at detecting variability among cocoa hybrids for bean index in Nigeria. Dried bean of fourteen genotypes of cocoa were evaluated for their bean values. Analysis of variance (ANOVA was used to understand the variability among the fourteen genotypes and Principal Component Analysis (PCA was employed to identify distinguishing traits and the grouping of the genotypes based on similarities. The fourteen cocoa genotypes were significantly (p≤0.05 different from each other with respect to weight of one bean, bean length, width, thickness, 100 bean weight, bean length to width, length to thickness and width to thickness ratio. All the studied morphometric characters exhibited high (>70% broad sense heritability. G8, the hybrid between T53/5 and N38 was the most superior genotype for bean weight and some other bean characteristics. The mass of seventy-four dried cocoa bean of G8 approximated 100 g. The first three Principal Component axes explained 91% of the total variation and the PCA grouped the fourteen genotypes into four distinct clusters. Genotypes could be selected for specific traits and improvement of traits seemed to be genetically reliable.

  10. Developmental Analysis of Genetic Behavior of Brown Rice Width in indica-japonica Hybrids

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xiao-ming; SHI Chun-hai; YE Shen-hai; QI Yong-bin

    2006-01-01

    The developmental genetic behaviors of brown rice width (BRW) have been studied in indica-japonica hybrid rice (Oryza sativa L.), in which seven indica male sterile lines and five japonica restorer lines were applied, by using the developmental genetic models and corresponding statistical approaches for quantitative traits of triploid in cereal crops. The BRW of indica-japonica hybrid rice was co-determined by gene expression of triploid endosperm, cytoplasm, diploid maternal plant and their genotype ×environmental interaction effects. Unconditional analysis showed that the endosperm additive and maternal additive effects were predominant for the development of BRW from early- to late-stage of the grain development, but the endosperm dominant effect together with maternal effect and cytoplasmic effect became the major factor determing the BRW at the ripening stage. Moreover,conditional analysis found that there were new onset and offset of gene expression at different developmental stages of BRW in indica-japonica hybrid rice. Maternal and cytoplasm general heritabilities and their interaction heritabilities were more important compared to other components of heritability for BRW at all the five developmental stages.

  11. Sensitivity Analysis of Hybrid Propulsion Transportation System for Human Mars Expeditions

    Science.gov (United States)

    Chai, Patrick R.; Joyce, Ryan T.; Kessler, Paul D.; Merrill, Raymond G.; Qu, Min

    2017-01-01

    The National Aeronautics and Space Administration continues to develop and refine various transportation options to successfully field a human Mars campaign. One of these transportation options is the Hybrid Transportation System which utilizes both solar electric propulsion and chemical propulsion. The Hybrid propulsion system utilizes chemical propulsion to perform high thrust maneuvers, where the delta-V is most optimal when ap- plied to save time and to leverage the Oberth effect. It then utilizes solar electric propulsion to augment the chemical burns throughout the interplanetary trajectory. This eliminates the need for the development of two separate vehicles for crew and cargo missions. Previous studies considered single point designs of the architecture, with fixed payload mass and propulsion system performance parameters. As the architecture matures, it is inevitable that the payload mass and the performance of the propulsion system will change. It is desirable to understand how these changes will impact the in-space transportation system's mass and power requirements. This study presents an in-depth sensitivity analysis of the Hybrid crew transportation system to payload mass growth and solar electric propulsion performance. This analysis is used to identify the breakpoints of the current architecture and to inform future architecture and campaign design decisions.

  12. A novel hybrid Neumann expansion method for stochastic analysis of mistuned bladed discs

    Science.gov (United States)

    Yuan, Jie; Allegri, Giuliano; Scarpa, Fabrizio; Patsias, Sophoclis; Rajasekaran, Ramesh

    2016-05-01

    The paper presents a novel hybrid method to enhance the computational efficiency of matrix inversions during the stochastic analysis of mistuned bladed disc systems. The method is based on the use of stochastic Neumann expansion in the frequency domain, coupled with a matrix factorization in the neighbourhood of the resonant frequencies. The number of the expansion terms is used as an indicator to select the matrix inversion technique to be used, without introducing any additional computational cost. The proposed method is validated using two case studies, where the dynamics an aero-engine bladed disc is modelled first using a lumped parameter approach and then with high-fidelity finite element analysis. The frequency responses of the blades are evaluated according to different mistuning patterns via stiffness or mass perturbations under the excitation provided by the engine orders. Results from standard matrix factorization methods are used to benchmark the responses obtained from the proposed hybrid method. Unlike classic Neumann expansion methods, the new technique can effectively update the inversion of an uncertain matrix with no convergence problems during Monte Carlo simulations. The novel hybrid method is more computationally efficient than standard techniques, with no accuracy loss.

  13. Thermoeconomic analysis of SOFC-GT hybrid systems fed by liquid fuels

    Energy Technology Data Exchange (ETDEWEB)

    Santin, Marco; Traverso, Alberto; Magistri, Loredana; Massardo, Aristide [TPG-DIMSET, University of Genoa, Via Montallegro 1, 16145 Genoa (Italy)

    2010-02-15

    In the distributed power generation market, Solid Oxide Fuel Cell-Gas Turbine (SOFC-GT) hybrids are an attractive option. Prototypes are being tested around the world with different types of fuel, but mainly natural gas. In this publication, a study of SOFC-GT hybrids for operation with liquid fuels is presented. Two liquid fuels were investigated, methanol and kerosene, in four layouts, taking into account different fuel processing strategies. A 500 kW class hybrid system (HS) was analysed. Web-based ThermoEconomic Modular Program (WTEMP) software, developed by the Thermochemical Power Group of the University of Genoa, was used for the thermodynamic and investment analysis. Performance was calculated based on zero-dimensional component models. The economic assessment was performed with a through-life cost analysis approach. The cost of the conventional components was calculated with WTEMP cost equations. As a final result, methanol-fuelled HSs are shown to stand out for both their thermodynamic and economic performance. (author)

  14. Meiotic analysis of interspecific hybrids between Capsicum frutescens and Capsicum chinense

    Directory of Open Access Journals (Sweden)

    Nádia Fernandes Moreira

    2017-04-01

    Full Text Available The aim of this study was to observe the genetic relationship between C. frutescens (UENF 1636 and C. chinense (UENF 1785 based on the meiotic behavior, on the meiotic index, and on pollen viability of their F1 hybrids. For meiotic analysis and meiotic index, flower buds were collected and fixed for 24 hours in ethanol: acetic acid (3:1, and then transferred to 70% ethanol, and stored in a freezer. Slides preparation for meiosis, meiotic index and pollen viability was carried out according to the laboratory’s protocol. Hybrid meiosis was regular, and 12 pairs of chromosomes were observed in diakinesis, as well as a few anomalies. The MI of 88.16%, as well as the pollen viability of 72.5%, were satisfactory. Given the results, it was confirmed the genetic proximity of these species, which are classified in the Capsicum annuum gene complex.

  15. Energy-saving analysis of hydraulic hybrid excavator based on common pressure rail.

    Science.gov (United States)

    Shen, Wei; Jiang, Jihai; Su, Xiaoyu; Karimi, Hamid Reza

    2013-01-01

    Energy-saving research of excavators is becoming one hot topic due to the increasing energy crisis and environmental deterioration recently. Hydraulic hybrid excavator based on common pressure rail (HHEC) provides an alternative with electric hybrid excavator because it has high power density and environment friendly and easy to modify based on the existing manufacture process. This paper is focused on the fuel consumption of HHEC and the actuator dynamic response to assure that the new system can save energy without sacrificing performance. Firstly, we introduce the basic principle of HHEC; then, the sizing process is presented; furthermore, the modeling period which combined mathematical analysis and experiment identification is listed. Finally, simulation results show that HHEC has a fast dynamic response which can be accepted in engineering and the fuel consumption can be reduced 21% to compare the original LS excavator and even 32% after adopting another smaller engine.

  16. Fluorescence Image Analyzer - FLIMA: software for quantitative analysis of fluorescence in situ hybridization.

    Science.gov (United States)

    Silva, H C M; Martins-Júnior, M M C; Ribeiro, L B; Matoso, D A

    2017-03-30

    The Fluorescence Image Analyzer (FLIMA) software was developed for the quantitative analysis of images generated by fluorescence in situ hybridization (FISH). Currently, the images of FISH are examined without a coefficient that enables a comparison between them. Through GD Graphics Library, the FLIMA software calculates the amount of pixels on image and recognizes each present color. The coefficient generated by the algorithm shows the percentage of marks (probes) hybridized on the chromosomes. This software can be used for any type of image generated by a fluorescence microscope and is able to quantify digoxigenin probes exhibiting a red color, biotin probes exhibiting a green color, and double-FISH probes (digoxigenin and biotin used together), where the white color is displayed.

  17. Hybrid FDTD Analysis for Periodic On-Chip Terahertz (THZ) Structures

    Energy Technology Data Exchange (ETDEWEB)

    Hussein, Yasser A.; Spencer, James E.; /SLAC

    2005-06-07

    We present electromagnetic analysis and radiation efficiency calculations for on-chip terahertz (THz) structures based on a hybrid, finite-difference, time-domain (HFDTD) technique. The method employs the FDTD technique to calculate S-parameters for one cell of a periodic structure. The transmission ABCD matrix is then estimated and multiplied by itself n times to obtain the n-cell periodic structure ABCD parameters that are then converted back to S-parameters. Validation of the method is carried out by comparing the results of the hybrid technique with FDTD calculations of the entire periodic structure as well as with HFSS which all agree quite well. This procedure reduces the CPU-time and allows efficient design and optimization of periodic THz radiation sources. Future research will involve coupling of Maxwell's equations with a more detailed, physics-based transport model for higher-order effects.

  18. Graphene coated fiber optic surface plasmon resonance biosensor for the DNA hybridization detection: Simulation analysis

    Science.gov (United States)

    Shushama, Kamrun Nahar; Rana, Md. Masud; Inum, Reefat; Hossain, Md. Biplob

    2017-01-01

    In this paper, a graphene coated optical fiber surface plasmon resonance (SPR) biosensor is presented for the detection of DNA Hybridization. For the proposed sensor, a four layer model (fiber core /metal /sensing layer /sample) where a sheet of graphene (biomolecular recognition elements (BRE)) acting as a sensing layer is coated around the gold film because graphene enhances the sensitivity of fiber optic SPR biosensor. Numerical analysis shows the variation of resonance wavelength and spectrum of transmitted power for mismatched DNA strands and for complementary DNA strands. For mismatched DNA strands variation is negligible whereas for complementary DNA strands is considerably countable. Proposed sensor successfully distinguishes hybridization and single nucleotide polymorphisms (SNP) by observing the variation level of resonance wavelength and spectrum of transmitted power.

  19. One hybrid model combining singular spectrum analysis and LS + ARMA for polar motion prediction

    Science.gov (United States)

    Shen, Yi; Guo, Jinyun; Liu, Xin; Wei, Xiaobei; Li, Wudong

    2017-01-01

    Accurate real-time polar motion parameters play an important role in satellite navigation and positioning and spacecraft tracking. To meet the needs for real-time and high-accuracy polar motion prediction, a hybrid model that integrated singular spectrum analysis (SSA), least-squares (LS) extrapolation and an autoregressive moving average (ARMA) model was proposed. SSA was applied to separate the trend, the annual and the Chandler components from a given polar motion time series. LS extrapolation models were constructed for the separated trend, annual and Chandler components. An ARMA model was established for a synthetic sequence that contained the remaining SSA component and the residual series of LS fitting. In applying this hybrid model, multiple sets of polar motion predictions with lead times of 360 days were made based on an IERS 08 C04 series. The results showed that the proposed method could effectively predict the polar motion parameters.

  20. Techno-economic analysis of a hybrid mini-grid system for Fiji islands

    Energy Technology Data Exchange (ETDEWEB)

    Lal, Sandeep; Raturi, Atul [Univ. of South Pacific, Suva (Fiji). School of Engineering and Physics

    2012-07-01

    The Pacific Island Countries constantly struggle with the challenges of high petroleum dependence for their electricity production and lack of adequate energy services. It is possible to alleviate the energy poverty by utilizing abundant renewable energy resources available in the region. The objective of this work is to investigate the feasibility of a wind/solar photovoltaic/diesel generator-based hybrid power system in a remote location in Fiji islands. We used the Hybrid Optimisation Model for Electric Renewables (HOMER) software to simulate the system and perform system optimisation analysis. The system characteristics were studied in terms of optimal configuration, net present cost and the cost of energy. An entirely renewable energy-based configuration is feasible if 10% annual capacity shortage is allowed, while for a scenario with no capacity shortage, addition of a diesel generator is necessary. The addition of renewable energy components results in greenhouse gas reduction which could be used for carbon trading. (orig.)

  1. Price competition and equilibrium analysis in multiple hybrid channel supply chain

    Science.gov (United States)

    Kuang, Guihua; Wang, Aihu; Sha, Jin

    2017-06-01

    The amazing boom of Internet and logistics industry prompts more and more enterprises to sell commodity through multiple channels. Such market conditions make the participants of multiple hybrid channel supply chain compete each other in traditional and direct channel at the same time. This paper builds a two-echelon supply chain model with a single manufacturer and a single retailer who both can choose different channel or channel combination for their own sales, then, discusses the price competition and calculates the equilibrium price under different sales channel selection combinations. Our analysis shows that no matter the manufacturer and retailer choose same or different channel price to compete, the equilibrium price does not necessarily exist the equilibrium price in the multiple hybrid channel supply chain and wholesale price change is not always able to coordinate supply chain completely. We also present the sufficient and necessary conditions for the existence of equilibrium price and coordination wholesale price.

  2. Feature-based Analysis of Large-scale Spatio-Temporal Sensor Data on Hybrid Architectures.

    Science.gov (United States)

    Saltz, Joel; Teodoro, George; Pan, Tony; Cooper, Lee; Kong, Jun; Klasky, Scott; Kurc, Tahsin

    2013-08-01

    Analysis of large sensor datasets for structural and functional features has applications in many domains, including weather and climate modeling, characterization of subsurface reservoirs, and biomedicine. The vast amount of data obtained from state-of-the-art sensors and the computational cost of analysis operations create a barrier to such analyses. In this paper, we describe middleware system support to take advantage of large clusters of hybrid CPU-GPU nodes to address the data and compute-intensive requirements of feature-based analyses in large spatio-temporal datasets.

  3. Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

    2016-01-01

    This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

  4. PolyA-Mediated DNA Assembly on Gold Nanoparticles for Thermodynamically Favorable and Rapid Hybridization Analysis.

    Science.gov (United States)

    Zhu, Dan; Song, Ping; Shen, Juwen; Su, Shao; Chao, Jie; Aldalbahi, Ali; Zhou, Ziang; Song, Shiping; Fan, Chunhai; Zuo, Xiaolei; Tian, Yang; Wang, Lianhui; Pei, Hao

    2016-05-03

    Understanding the behavior of biomolecules on nanointerface is critical in bioanalysis, which is great challenge due to the instability and the difficulty to control the orientation and loading density of biomolecules. Here, we investigated the thermodynamics and kinetics of DNA hybridization on gold nanoparticle, with the aim to improve the efficiency and speed of DNA analysis. We achieved precise and quantitative surface control by applying a recently developed poly adenines (polyA)-based assembly strategy on gold nanoparticles (DNA-AuNPs). PolyA served as an effective anchoring block based on the preferential binding with the AuNP surface and the appended recognition block adopted an upright conformation that favors DNA hybridization. The lateral spacing and surface density of DNA on AuNPs can be systematically modulated by adjusting the length of polyA block. We found the stability of duplex on AuNP was enhanced with the increasing length of polyA block. When the length of polyA block reached to 40 bases, the thermodynamic properties were more similar to that of duplex in solution. Fast hybridization rate was observed on the diblock DNA-AuNPs and was increased along with the length of polyA block. We consider the high stability and excellent hybridization performance come from the minimization of the DNA-DNA and DNA-AuNP interactions with the use of polyA block. This study provides better understanding of the behavior of biomolecules on the nanointerface and opens new opportunities to construct high-efficiency and high-speed biosensors for DNA analysis.

  5. GISH, AFLP and PCR-RFLP analysis of an intergeneric somatic hybrid combining Goutou sour orange and Poncirus trifoliata.

    Science.gov (United States)

    Fu, C H; Chen, C L; Guo, W W; Deng, X X

    2004-11-01

    Intergeneric somatic hybrids combining Goutou sour orange (Citrus aurantium L.) with trifoliate orange Poncirus trifoliata (L.) Raf] were produced by electrofusion and their genetic inheritance analyzed by amplified fragment length polymorphism (AFLP), genomic in situ hybridization (GISH), and PCR-restriction fragment length polymorphism (PCR-RFLP). Sixteen mini-calluses were obtained after 20 days of culture; they all developed into embryoids on EME500 medium. Following several subcultures on shoot induction medium for a total culture period of 6 months, shoots regenerated. The plants grew vigorously with a well-developed root system and exhibited the trifoliate leaf character of P. trifoliata. Ploidy analysis verified that all of the regenerates were tetraploids (2 n=4 x=36) as expected. GISH analysis confirmed that 18 chromosomes came from trifoliate orange and the remaining 18 from Goutou sour orange, as with most symmetric somatic hybrid plants; moreover, chromosome translocations were also observed in one plant. AFLP analysis of 16 regenerates and their fusion parents indicated that all of the somatic hybrids except one were genetically uniform. Analysis of the somatic hybrid cytoplasmic genomes with universal primers revealed that their chloroplast DNA (cpDNA) banding patterns were identical to those of the mesophyll parent trifoliate orange, while their mitochondria (mt) genomes were of the callus parent sour orange. The potential of GISH in Citrus somatic hybrid analysis is discussed.

  6. Expressed sequence tag analysis of functional genes associated with adventitious rooting in Liriodendron hybrids.

    Science.gov (United States)

    Zhong, Y D; Sun, X Y; Liu, E Y; Li, Y Q; Gao, Z; Yu, F X

    2016-06-24

    Liriodendron hybrids (Liriodendron chinense x L. tulipifera) are important landscaping and afforestation hardwood trees. To date, little genomic research on adventitious rooting has been reported in these hybrids, as well as in the genus Liriodendron. In the present study, we used adventitious roots to construct the first cDNA library for Liriodendron hybrids. A total of 5176 expressed sequence tags (ESTs) were generated and clustered into 2921 unigenes. Among these unigenes, 2547 had significant homology to the non-redundant protein database representing a wide variety of putative functions. Homologs of these genes regulated many aspects of adventitious rooting, including those for auxin signal transduction and root hair development. Results of quantitative real-time polymerase chain reaction showed that AUX1, IRE, and FB1 were highly expressed in adventitious roots and the expression of AUX1, ARF1, NAC1, RHD1, and IRE increased during the development of adventitious roots. Additionally, 181 simple sequence repeats were identified from 166 ESTs and more than 91.16% of these were dinucleotide and trinucleotide repeats. To the best of our knowledge, the present study reports the identification of the genes associated with adventitious rooting in the genus Liriodendron for the first time and provides a valuable resource for future genomic studies. Expression analysis of selected genes could allow us to identify regulatory genes that may be essential for adventitious rooting.

  7. Performance Analysis of a Hybrid Overset Multi-Block Application on Multiple Architectures

    Science.gov (United States)

    Djomehri, M. Jahed; Biswas, Rupak

    2003-01-01

    This paper presents a detailed performance analysis of a multi-block overset grid compu- tational fluid dynamics app!ication on multiple state-of-the-art computer architectures. The application is implemented using a hybrid MPI+OpenMP programming paradigm that exploits both coarse and fine-grain parallelism; the former via MPI message passing and the latter via OpenMP directives. The hybrid model also extends the applicability of multi-block programs to large clusters of SNIP nodes by overcoming the restriction that the number of processors be less than the number of grid blocks. A key kernel of the application, namely the LU-SGS linear solver, had to be modified to enhance the performance of the hybrid approach on the target machines. Investigations were conducted on cacheless Cray SX6 vector processors, cache-based IBM Power3 and Power4 architectures, and single system image SGI Origin3000 platforms. Overall results for complex vortex dynamics simulations demonstrate that the SX6 achieves the highest performance and outperforms the RISC-based architectures; however, the best scaling performance was achieved on the Power3.

  8. MULTICRITERIA HYBRID FLOW SHOP SCHEDULING PROBLEM: LITERATURE REVIEW, ANALYSIS, AND FUTURE RESEARCH

    Directory of Open Access Journals (Sweden)

    Marcia de Fatima Morais

    2014-12-01

    Full Text Available This research focuses on the Hybrid Flow Shop production scheduling problem, which is one of the most difficult problems to solve. The literature points to several studies that focus the Hybrid Flow Shop scheduling problem with monocriteria functions. Despite of the fact that, many real world problems involve several objective functions, they can often compete and conflict, leading researchers to concentrate direct their efforts on the development of methods that take consider this variant into consideration. The goal of the study is to review and analyze the methods in order to solve the Hybrid Flow Shop production scheduling problem with multicriteria functions in the literature. The analyses were performed using several papers that have been published over the years, also the parallel machines types, the approach used to develop solution methods, the type of method develop, the objective function, the performance criterion adopted, and the additional constraints considered. The results of the reviewing and analysis of 46 papers showed opportunities for future research on this topic, including the following: (i use uniform and dedicated parallel machines, (ii use exact and metaheuristics approaches, (iv develop lower and uppers bounds, relations of dominance and different search strategies to improve the computational time of the exact methods,  (v develop  other types of metaheuristic, (vi work with anticipatory setups, and (vii add constraints faced by the production systems itself.

  9. Three-dimensional hybrid-stress finite element analysis of composite laminates with cracks and cutouts

    Science.gov (United States)

    Wang, S. S.

    1985-01-01

    A three-dimensional hybrid-stress finite element analysis of composite laminates containing cutouts and cracks is presented. Fully three-dimensional, hexahedral isoparametric elements of the hybrid-stress model are formulated on the basis of the Hellinger-Reissner variational principle. Traction-free edges, cutouts, and crack surfaces are modeled by imposition of exact traction boundary conditions along element surfaces. Special boundary and surface elements are constructed by introducing proper constraints on assumed stress functions. The Lagrangian multiplier technique is used to enforce ply-interface continuity conditions in hybrid bimaterial composite elements for modeling the interface region in a composite laminate. Two examples are given to illustrate the capability of the present method of approach: (1) the well-known delamination problem in an angle-ply laminate, and (2) the important problem of a composite laminate containing a circular hole. Results are presented in detail for each case. Implications of interlaminar and intralaminar crack initiation, growth and fracture in composites containing cracks and cutouts are discussed.

  10. Characteristic Analysis and Control of a Hybrid Excitation Linear Eddy Current Brake

    Directory of Open Access Journals (Sweden)

    Baoquan Kou

    2015-07-01

    Full Text Available In this paper, a novel hybrid excitation linear eddy current brake is presented as a braking system for high-speed road and rail vehicles. The presence of the permanent magnets (PMs, whose flux lines in the primary core are oppositely directed with respect to the flux lines by the excitation windings, has the effect of mitigating the saturation of the iron in the teeth of the primary core. This allows the brake to be fed with more intense currents, improving the braking force. First, using the magnetic equivalent circuit method and the layer theory approach, the analytical model of the hybrid excitation linear eddy current brake was developed, which can account for the saturation effects occurring in the iron parts. The saturation effects make the design and control of eddy current brakes more difficult. Second, the relationship between the braking force characteristics and the design parameters were analyzed to provide useful information to the designers of eddy current brakes. Then, the controller of the hybrid excitation linear eddy current brake was designed to control the amplitude of the braking force. Finally, experimental measurements were conducted to verify the validity of the theoretical analysis.

  11. Thermoeconomic analysis of pressurized hybrid SOFC systems with CO{sub 2} separation

    Energy Technology Data Exchange (ETDEWEB)

    Franzoni, A.; Magistri, L.; Traverso, A.; Massardo, A.F. [TPG-DiMSET, Universita di Genova, via Montallegro 1, 16145 Genoa (Italy)

    2008-02-15

    In this paper, the results of the thermodynamic and economic analyses of distributed power generation plants (1.5 MWe) are described and compared. The results of an exergetic analysis are also reported, as well as the thermodynamic details of the most significant streams of the plants. The integration of different hybrid solid oxide fuel cell (SOFC) system CO{sub 2} separation technologies characterizes the power plants proposed. A hybrid system with a tubular SOFC fed with natural gas with internal reforming has been taken as reference plant. Two different technologies have been considered for the same base system to obtain a low CO{sub 2} emission plant. The first technology involved a fuel decarbonization and CO{sub 2} separation process placed before the system feed, while the second integrated the CO{sub 2} separation and the energy cycle. The first option employed fuel processing, a technology (amine chemical absorption) viable for short-term implementation in real installations while the second option provided the CO{sub 2} separation by condensing the steam from the system exhaust. The results obtained, using a Web-based Thermo Economic Modular Program software, developed by the Thermochemical Power Group of the University of Genoa, showed that the thermodynamic and economic impact of the adoption of zero emission cycle layouts based on hybrid systems was relevant. (author)

  12. Analysis of Chinese women with primary ovarian insufficiency by high resolution array-comparative genomic hybridization

    Institute of Scientific and Technical Information of China (English)

    LIAO Can; FU Fang; YANG Xin; SUN Yi-min; LI Dong-zhi

    2011-01-01

    Background Primary ovarian insufficiency (POI) is defined as a primary ovarian defect characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles before the age of 40 years. The etiology of primary ovarian insufficiency in human female patients is still unclear. The purpose of this study is to investigate the potential genetic causes in primary amenorrhea patients by high resolution array based comparative genomic hybridization (array-CGH) analysis.Methods Following the standard karyotyping analysis, genomic DNA from whole blood of 15 primary amenorrhea patients and 15 normal control women was hybridized with Affymetrix cytogenetic 2.7M arrays following the standard protocol. Copy number variations identified by array-CGH were confirmed by real time polymerase chain reaction.Results All the 30 samples were negative by conventional karyotyping analysis. Microdeletions on chromosome 17q21.31-q21.32 with approximately 1.3 Mb were identified in four patients by high resolution array-CGH analysis. This included the female reproductive secretory pathway related factor N-ethylmaleimide-sensitive factor (NSF) gene.Conclusions The results of the present study suggest that there may be critical regions regulating primary ovarian insufficiency in women with a 17q21.31-q21.32 microdeletion. This effect might be due to the loss of function of the NSF gene/genes within the deleted region or to effects on contiguous genes.

  13. Computational analysis of electrical conduction in hybrid nanomaterials with embedded non-penetrating conductive particles

    Science.gov (United States)

    Cai, Jizhe; Naraghi, Mohammad

    2016-08-01

    In this work, a comprehensive multi-resolution two-dimensional (2D) resistor network model is proposed to analyze the electrical conductivity of hybrid nanomaterials made of insulating matrix with conductive particles such as CNT reinforced nanocomposites and thick film resistors. Unlike existing approaches, our model takes into account the impenetrability of the particles and their random placement within the matrix. Moreover, our model presents a detailed description of intra-particle conductivity via finite element analysis, which to the authors’ best knowledge has not been addressed before. The inter-particle conductivity is assumed to be primarily due to electron tunneling. The model is then used to predict the electrical conductivity of electrospun carbon nanofibers as a function of microstructural parameters such as turbostratic domain alignment and aspect ratio. To simulate the microstructure of single CNF, randomly positioned nucleation sites were seeded and grown as turbostratic particles with anisotropic growth rates. Particle growth was in steps and growth of each particle in each direction was stopped upon contact with other particles. The study points to the significant contribution of both intra-particle and inter-particle conductivity to the overall conductivity of hybrid composites. Influence of particle alignment and anisotropic growth rate ratio on electrical conductivity is also discussed. The results show that partial alignment in contrast to complete alignment can result in maximum electrical conductivity of whole CNF. High degrees of alignment can adversely affect conductivity by lowering the probability of the formation of a conductive path. The results demonstrate approaches to enhance electrical conductivity of hybrid materials through controlling their microstructure which is applicable not only to carbon nanofibers, but also many other types of hybrid composites such as thick film resistors.

  14. Fuel cycle analysis based evaluation of the fuel and emissions reduction potential of adapting the hybrid technology to tricycles

    Energy Technology Data Exchange (ETDEWEB)

    Biona, J.B.M. [Don Bosco Technical College, Mandaluyong City (Philippines); De La Salle University, Center for Engineering and Sustainable Development Research, Manila (Philippines); Culaba, A.B. [De La Salle University, Center for Engineering and Sustainable Development Research, Manila (Philippines); Purvis, M.R.I. [University of Portsmouth, Department of Mechanical Design and Engineering, Portsmouth (United Kingdom)

    2008-02-15

    A preliminary analysis has been conducted to investigate the fuel use and emissions reduction potential of incorporating hybrid systems to two stroke powered tricycles in Metro Manila. Carbureted and direct injection two stroke engine hybrid systems were investigated and compared with the impact of shifting to four stroke engines. Results showed that hybridized direct injection retrofitted two stroke powered systems would be able to provide far better environmental and fuel reduction benefits than the shift to new four strokes tricycles. It is thus recommended that the development of such technology specifically for tricycles be seriously pursued. (orig.)

  15. General and hybrid correlation nuclear magnetic resonance analysis of phosphorus in Phytophthora palmivora.

    Science.gov (United States)

    Kirwan, Gemma M; Fernandez, David I; Niere, Julie O; Adams, Michael J

    2012-10-01

    Generalized two-dimensional (Gen2D) correlation analysis and hybrid correlation analysis have been applied to a series of dynamic (31)P nuclear magnetic resonance (NMR) spectra to monitor the in vivo metabolic changes of the plant pathogen Phytophthora palmivora in the presence and absence of phosphonate over an 18-h period. Results indicate that phosphonate exposure causes cleavage in organism polyphosphate chains as well as an increase in total sugar phosphates. In the presence of phosphonate, the NMR resonances attributed to terminal polyphosphate phosphorus reduced at a lower rate than those of middle polyphosphate phosphorus, indicating a change in average chain length and suggesting cleavage in the middle of the chain as well as at the ends. The correlation analysis techniques serve to identify and confirm spectral regions undergoing major change in the time-series data and facilitate the analysis of these dynamic changes.

  16. A HYBRID SYSTEM FOR DYNAMIC ANALYSIS AND DESIGN OF COUPLED SHEAR WALLS

    Directory of Open Access Journals (Sweden)

    A BERRAIS

    2000-06-01

    Full Text Available Non-linear dynamic analysis techniques are rapidly being developed and have been recognized as indispensable tools. However, their use in the design office requires special experience. Consequently they are not generally accepted as analysis/design tools. Additionally, uncertainties are associated with the determination of the earthquake forces, the stiffness and strength of the structure; the selection of the mathematical models; and the form of the earthquake. In this paper a hybrid system for the non-linear dynamic analysis/design of coupled shear walls is briefly described. The system combines expert system technology with finite element method to carry out the dynamic analysis of coupled walls under earthquake forces. The system has been implemented using Quintec-Prolog, Quintec-Flex and FORTRAN 77, and runs on a SUN SPARC station under Unix system.

  17. An efficient hybrid reliability analysis method with random and interval variables

    Science.gov (United States)

    Xie, Shaojun; Pan, Baisong; Du, Xiaoping

    2016-09-01

    Random and interval variables often coexist. Interval variables make reliability analysis much more computationally intensive. This work develops a new hybrid reliability analysis method so that the probability analysis (PA) loop and interval analysis (IA) loop are decomposed into two separate loops. An efficient PA algorithm is employed, and a new efficient IA method is developed. The new IA method consists of two stages. The first stage is for monotonic limit-state functions. If the limit-state function is not monotonic, the second stage is triggered. In the second stage, the limit-state function is sequentially approximated with a second order form, and the gradient projection method is applied to solve the extreme responses of the limit-state function with respect to the interval variables. The efficiency and accuracy of the proposed method are demonstrated by three examples.

  18. Numerical analysis of the forced convective heat transfer on Al2O3-Cu/water hybrid nanofluid

    Science.gov (United States)

    Rahman, Mohd Rosdzimin Abdul; Leong, Kin Yuen; Idris, Azam Che; Saad, Mohd Rashdan; Anwar, Mahmood

    2017-05-01

    A numerical investigation to elucidate thermal behavior of hybrid nanofluids consisting of Al2O3 and Cu nanoparticles at ratio of 90:10 was conducted. Numerical domain of a two-dimensional axisymmetric copper tube with a length of 1000 and 10 mm in diameter is used. A uniform axial velocity is assigned at the velocity inlet based on the Reynolds number. The outer wall of the tube consists of non-slip wall condition with a constant heat flux. The assumptions of this numerical analysis are; (1) there is a steady state analysis, (2) effective thermo-physical properties of the nanofluid are depend on the volume concentration, and (3) fluid is continuum. It is found that the dominant nanoparticle in the hybrid nanofluids strongly influences the thermal behavior of the hybrid nanofluids. It was also found that the heat transfer coefficient increases as the volume concentration of the hybrid nanoparticle increases in base fluids and the Reynolds number.

  19. Small-Signal Analysis of Autonomous Hybrid Distributed Generation Systems in Presence of Ultracapacitor and Tie-Line Operation

    Science.gov (United States)

    Ray, Prakash K.; Mohanty, Soumya R.; Kishor, Nand

    2010-07-01

    This paper presents small-signal analysis of isolated as well as interconnected autonomous hybrid distributed generation system for sudden variation in load demand, wind speed and solar radiation. The hybrid systems comprise of different renewable energy resources such as wind, photovoltaic (PV) fuel cell (FC) and diesel engine generator (DEG) along with the energy storage devices such as flywheel energy storage system (FESS) and battery energy storage system (BESS). Further ultracapacitors (UC) as an alternative energy storage element and interconnection of hybrid systems through tie-line is incorporated into the system for improved performance. A comparative assessment of deviation of frequency profile for different hybrid systems in the presence of different storage system combinations is carried out graphically as well as in terms of the performance index (PI), ie integral square error (ISE). Both qualitative and quantitative analysis reflects the improvements of the deviation in frequency profiles in the presence of the ultracapacitors (UC) as compared to other energy storage elements.

  20. Molecular Cytogenetic Analysis of Spontaneous Interspecific Hybrid Between Oryza sativa and Oryza minuta

    Directory of Open Access Journals (Sweden)

    Chuan-deng YI

    2008-12-01

    Full Text Available Genomic in situ hybridization (GISH is a powerful tool to characterize parental chromosomes in interspecific hybrids, including the behaviour of autosynapsis and chromosome pairing. It was used to distinguish the chromosomes of Oryza sativa from wild species in a spontaneous interspecific hybrid and to investigate the chromosome pairing at metaphase I in meiosis of the hybrid in this study. The hybrid was a triploid with 36 chromosomes according to the chromosome number investigated in mitosis of root tips. During metaphase I of meiosis in the hybrid, less chromosome pairing was observed and most of the chromosomes existed as univalent. Based on GISH and FISH (Fluorescent in situ hybridization analyses, the chromosomes of the hybrid were composed of genomes A, B and C. Thus, it was believed that the hybrid was the result of natural hybridization between cultivated rice and wild species O. minuta which was planted in experimental fields.

  1. Hybrid optimization for 13C metabolic flux analysis using systems parametrized by compactification

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    Frick Oliver

    2008-03-01

    Full Text Available Abstract Background The importance and power of isotope-based metabolic flux analysis and its contribution to understanding the metabolic network is increasingly recognized. Its application is, however, still limited partly due to computational inefficiency. 13C metabolic flux analysis aims to compute in vivo metabolic fluxes in terms of metabolite balancing extended by carbon isotopomer balances and involves a nonlinear least-squares problem. To solve the problem more efficiently, improved numerical optimization techniques are necessary. Results For flux computation, we developed a gradient-based hybrid optimization algorithm. Here, independent flux variables were compactified into [0, 1-ranged variables using a single transformation rule. The compactified parameters could be discriminated between non-identifiable and identifiable variables after model linearization. The developed hybrid algorithm was applied to the central metabolism of Bacillus subtilis with only succinate and glutamate as carbon sources. This creates difficulties caused by symmetry of succinate leading to limited introduction of 13C labeling information into the system. The algorithm was found to be superior to its parent algorithms and to global optimization methods both in accuracy and speed. The hybrid optimization with tolerance adjustment quickly converged to the minimum with close to zero deviation and exactly re-estimated flux variables. In the metabolic network studied, some fluxes were found to be either non-identifiable or nonlinearly correlated. The non-identifiable fluxes could correctly be predicted a priori using the model identification method applied, whereas the nonlinear flux correlation was revealed only by identification runs using different starting values a posteriori. Conclusion This fast, robust and accurate optimization method is useful for high-throughput metabolic flux analysis, a posteriori identification of possible parameter correlations, and

  2. Well-posedness and stability analysis of hybrid feedback systems using Shkalikov's theory

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    Piotr Grabowski

    2006-01-01

    Full Text Available The modern method of analysis of the distributed parameter systems relies on the transformation of the dynamical model to an abstract differential equation on an appropriately chosen Banach or, if possible, Hilbert space. A linear dynamical model in the form of a first order abstract differential equation is considered to be well-posed if its right-hand side generates a strongly continuous semigroup. Similarly, a dynamical model in the form of a second order abstract differential equation is well-posed if its right-hand side generates a strongly continuous cosine family of operators. Unfortunately, the presence of a feedback leads to serious complications or even excludes a direct verification of assumptions of the Hille-Phillips-Yosida and/or the Sova-Fattorini Theorems. The class of operators which are similar to a normal discrete operator on a Hilbert space describes a wide variety of linear operators. In the papers [Grabowski P., Well–posedness and stability analysis of hybrid feedback systems, Journal of Mathematical Systems, Estimation and Control 6 (1996, 121–124 (summary, full electronic manuscript – retrieval code 15844, Grabowski P., Spectral approach to well–posedness and stability analysis of hybrid feedback systems, In: Wajs W., Grabowski P. (Eds., Studies in Automatics, 1996, Kraków, Wydawnictwa AGH, 104–139] two groups of similarity criteria for a given hybrid closed-lop system operator are given. The criteria of the first group are based on some perturbation results, and of the second, on the application of Shkalikov's theory of the Sturm-Liouville eigenproblems with a spectral parameter in the boundary conditions. In the present paper we continue those investigations showing certain advanced applications of the Shkalikov's theory. The results are illustrated by feedback control systems examples governed by wave and beam equations with increasing degree of complexity of the boundary conditions.

  3. Hybrid Bernstein Block-Pulse Functions Method for Second Kind Integral Equations with Convergence Analysis

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    Mohsen Alipour

    2014-01-01

    Full Text Available We introduce a new combination of Bernstein polynomials (BPs and Block-Pulse functions (BPFs on the interval [0, 1]. These functions are suitable for finding an approximate solution of the second kind integral equation. We call this method Hybrid Bernstein Block-Pulse Functions Method (HBBPFM. This method is very simple such that an integral equation is reduced to a system of linear equations. On the other hand, convergence analysis for this method is discussed. The method is computationally very simple and attractive so that numerical examples illustrate the efficiency and accuracy of this method.

  4. Hybrid-finite-element analysis of some nonlinear and 3-dimensional problems of engineering fracture mechanics

    Science.gov (United States)

    Atluri, S. N.; Nakagaki, M.; Kathiresan, K.

    1980-01-01

    In this paper, efficient numerical methods for the analysis of crack-closure effects on fatigue-crack-growth-rates, in plane stress situations, and for the solution of stress-intensity factors for arbitrary shaped surface flaws in pressure vessels, are presented. For the former problem, an elastic-plastic finite element procedure valid for the case of finite deformation gradients is developed and crack growth is simulated by the translation of near-crack-tip elements with embedded plastic singularities. For the latter problem, an embedded-elastic-singularity hybrid finite element method, which leads to a direct evaluation of K-factors, is employed.

  5. Parametric study and performance analysis of hybrid rocket motors with double-tube configuration

    Science.gov (United States)

    Yu, Nanjia; Zhao, Bo; Lorente, Arnau Pons; Wang, Jue

    2017-03-01

    The practical implementation of hybrid rocket motors has historically been hampered by the slow regression rate of the solid fuel. In recent years, the research on advanced injector designs has achieved notable results in the enhancement of the regression rate and combustion efficiency of hybrid rockets. Following this path, this work studies a new configuration called double-tube characterized by injecting the gaseous oxidizer through a head end injector and an inner tube with injector holes distributed along the motor longitudinal axis. This design has demonstrated a significant potential for improving the performance of hybrid rockets by means of a better mixing of the species achieved through a customized injection of the oxidizer. Indeed, the CFD analysis of the double-tube configuration has revealed that this design may increase the regression rate over 50% with respect to the same motor with a conventional axial showerhead injector. However, in order to fully exploit the advantages of the double-tube concept, it is necessary to acquire a deeper understanding of the influence of the different design parameters in the overall performance. In this way, a parametric study is carried out taking into account the variation of the oxidizer mass flux rate, the ratio of oxidizer mass flow rate injected through the inner tube to the total oxidizer mass flow rate, and injection angle. The data for the analysis have been gathered from a large series of three-dimensional numerical simulations that considered the changes in the design parameters. The propellant combination adopted consists of gaseous oxygen as oxidizer and high-density polyethylene as solid fuel. Furthermore, the numerical model comprises Navier-Stokes equations, k-ε turbulence model, eddy-dissipation combustion model and solid-fuel pyrolysis, which is computed through user-defined functions. This numerical model was previously validated by analyzing the computational and experimental results obtained for

  6. FEM-based Analysis of a Hybrid Synchronous Generator with Skewed Stator Slots

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    MUNTEANU, A.

    2011-11-01

    Full Text Available The paper presents a simulation study of a hybrid synchronous generator (dual excitation system - permanent magnets and electromagnets with skewed stator slots. The main goal is to establish if the skewing of the slots brings a significant improvement of the air-gap flux density and of the induced stator voltage. The skewness angle is the parameter in discussion. The study is based on finite element method analysis. Due to the particular geometry of the stator slots, a multilayer approach is employed.

  7. Identification of differentially expressed genes in rat silicosis model by suppression subtractive hybridization analysis

    Institute of Scientific and Technical Information of China (English)

    Zhongyuan Jin; Chunyan Fu; Jifang Wen; Baoan Liu; Deyun Feng; Chen Chen; Xiang Li; Yongbin Hu; Jinwu Peng; Yu Liu; Jing Du

    2008-01-01

    The critical molecular mechanism in the development of the pulmonary fibrosis remains unknown, leaving diagnosed patients with a poor prognosis. To isolate the genes specifi-cally up-regulated in pulmonary fibrosis, we established a rat silicosis model 360 d after treatment with crystalline silica suspension. Radiographs of chests showed that some scattered high-density shadows appeared in the lung field.Typical microscopic fibrosing silicotic nodules formed in the lung,alveolar epithelial cells and bronchial epithelial cells,particularly around the partial fibrosing silicotic nodules;some of them showed atypical hyperplasia that suggested a correlation between silicosis and lung cancer.Suppression subtractive hybridization analysis was performed to compare gene expression in lung tissue with silicosis and normal lung tissue.Reverse transcription-polymerase chain rection showed that the expressions of seven novel cDNA sequences identified by suppression subtractive hybridization in lung tissue with silicosis differed from normal lung tissue. Bioinformatics analysis showed that 47 positive clones rep-resented 35 genes containing two putative proteins and four predicted similar proteins.The analysis also showed that some screened genes in silicosis,such as prolyl 4-hydroxylases,actin-related protein-2/3 complex and acidic mammalian chitinase,have not been previously reported.These genes may provide new clues for investigating the molecular mechanisms in the development of pulmonary fibrosis.

  8. Earthscape, a Multi-Purpose Interactive 3d Globe Viewer for Hybrid Data Visualization and Analysis

    Science.gov (United States)

    Sarthou, A.; Mas, S.; Jacquin, M.; Moreno, N.; Salamon, A.

    2015-08-01

    The hybrid visualization and interaction tool EarthScape is presented here. The software is able to display simultaneously LiDAR point clouds, draped videos with moving footprint, volume scientific data (using volume rendering, isosurface and slice plane), raster data such as still satellite images, vector data and 3D models such as buildings or vehicles. The application runs on touch screen devices such as tablets. The software is based on open source libraries, such as OpenSceneGraph, osgEarth and OpenCV, and shader programming is used to implement volume rendering of scientific data. The next goal of EarthScape is to perform data analysis using ENVI Services Engine, a cloud data analysis solution. EarthScape is also designed to be a client of Jagwire which provides multisource geo-referenced video fluxes. When all these components will be included, EarthScape will be a multi-purpose platform that will provide at the same time data analysis, hybrid visualization and complex interactions. The software is available on demand for free at france@exelisvis.com.

  9. EARTHSCAPE, A MULTI-PURPOSE INTERACTIVE 3D GLOBE VIEWER FOR HYBRID DATA VISUALIZATION AND ANALYSIS

    Directory of Open Access Journals (Sweden)

    A. Sarthou

    2015-08-01

    Full Text Available The hybrid visualization and interaction tool EarthScape is presented here. The software is able to display simultaneously LiDAR point clouds, draped videos with moving footprint, volume scientific data (using volume rendering, isosurface and slice plane, raster data such as still satellite images, vector data and 3D models such as buildings or vehicles. The application runs on touch screen devices such as tablets. The software is based on open source libraries, such as OpenSceneGraph, osgEarth and OpenCV, and shader programming is used to implement volume rendering of scientific data. The next goal of EarthScape is to perform data analysis using ENVI Services Engine, a cloud data analysis solution. EarthScape is also designed to be a client of Jagwire which provides multisource geo-referenced video fluxes. When all these components will be included, EarthScape will be a multi-purpose platform that will provide at the same time data analysis, hybrid visualization and complex interactions. The software is available on demand for free at france@exelisvis.com.

  10. Multicolor in situ hybridization and linkage analysis order Charcot-Marie-Tooth type I (CMTIA) gene-region markers

    Energy Technology Data Exchange (ETDEWEB)

    Lebo, R.V.; Lynch, E.D.; Golbus, M.S. (Univ. of California, San Francisco (United States)); Bird, T.D. (Univ. of Washington, Seattle (United States)); Barker, D.F.; O' Connell, P.; Chance, P.F. (Univ. of Utah, Salt Lake City (United States))

    1992-01-01

    This study demonstrates a clear and current role for multicolor in situ hybridization in expediting positional cloning studies of unknown disease genes. Nine polymorphic DNA cosmids have been mapped to eight ordered locations spanning the Charcot-Marie-Tooth type 1 (CMT1A) disease gene region in distal band 17p11.2, by multicolor in situ hybridization. When used with linkage analysis, these methods have generated a fine physical map and have firmly assigned the CMT1A gene to distal band 17p11.2. Linkage analysis with four CMT1A pedigrees mapped the CMT1A gene with respect to two flanking markers. Additional loci were physically mapped and ordered by in situ hybridization and analysis of phase-known recombinants in CMT1A pedigrees. These data demonstrate the ability of in situ hybridization to resolve loci within 0.5 Mb on early-metaphase chromosomes. Multicolor in situ hybridization also excluded the possibility of pericentric inversions in two unrelated patients with CMT1 and neurofibromatosis type 1. When used with pulsed-field gel electrophoresis, multicolor in situ hybridization can establish physical location, order, and distance in closely spaced chromosome loci.

  11. Hybrid transfinite element modeling/analysis of nonlinear heat conduction problems involving phase change

    Science.gov (United States)

    Tamma, Kumar K.; Railkar, Sudhir B.

    1988-01-01

    The present paper describes the applicability of hybrid transfinite element modeling/analysis formulations for nonlinear heat conduction problems involving phase change. The methodology is based on application of transform approaches and classical Galerkin schemes with finite element formulations to maintain the modeling versatility and numerical features for computational analysis. In addition, in conjunction with the above, the effects due to latent heat are modeled using enthalpy formulations to enable a physically realistic approximation to be dealt computationally for materials exhibiting phase change within a narrow band of temperatures. Pertinent details of the approach and computational scheme adapted are described in technical detail. Numerical test cases of comparative nature are presented to demonstrate the applicability of the proposed formulations for numerical modeling/analysis of nonlinear heat conduction problems involving phase change.

  12. pISTil: a pipeline for yeast two-hybrid Interaction Sequence Tags identification and analysis

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    de Chassey Benoît

    2009-10-01

    Full Text Available Abstract Background High-throughput screening of protein-protein interactions opens new systems biology perspectives for the comprehensive understanding of cell physiology in normal and pathological conditions. In this context, yeast two-hybrid system appears as a promising approach to efficiently reconstruct protein interaction networks at the proteome-wide scale. This protein interaction screening method generates a large amount of raw sequence data, i.e. the ISTs (Interaction Sequence Tags, which urgently need appropriate tools for their systematic and standardised analysis. Findings We develop pISTil, a bioinformatics pipeline combined with a user-friendly web-interface: (i to establish a standardised system to analyse and to annotate ISTs generated by two-hybrid technologies with high performance and flexibility and (ii to provide high-quality protein-protein interaction datasets for systems-level approach. This pipeline has been validated on a large dataset comprising more than 11.000 ISTs. As a case study, a detailed analysis of ISTs obtained from yeast two-hybrid screens of Hepatitis C Virus proteins against human cDNA libraries is also provided. Conclusion We have developed pISTil, an open source pipeline made of a collection of several applications governed by a Perl script. The pISTil pipeline is intended to laboratories, with IT-expertise in system administration, scripting and database management, willing to automatically process large amount of ISTs data for accurate reconstruction of protein interaction networks in a systems biology perspective. pISTil is publicly available for download at http://sourceforge.net/projects/pistil.

  13. Multilayer interparticle linking hybrid MOF-199 for noninvasive enrichment and analysis of plant hormone ethylene.

    Science.gov (United States)

    Zhang, Zhuomin; Huang, Yichun; Ding, Weiwei; Li, Gongke

    2014-04-01

    Ethylene, an important plant hormone, is of utmost importance during many developmental processes of plants. However, the efficient enrichment and analysis of trace ethylene still remains a challenge. A simple and mild multilayer interparticle linking strategy was proposed to fabricate a novel hybrid MOF-199 enrichment coating. Strong chemical interparticle linkages throughout the coating improved the durability and reproducibility of hybrid MOF-199 coating dramatically. This coating performed a significant extraction superiority of ethylene over commonly used commercial coatings, attributed to the multiple interactions including "molecular sieving effect", hydrogen bonding, open metal site interaction, and π-π affinity. The hybridization of multiwalled carbon nanotubes (MWCNTs) with MOF-199 further improved the enrichment capability and also acted as a hydrophobic "shield" to prevent the open metal sites of MOF-199 from being occupied by water molecules, which effectively improved the moisture-resistant property of MOF-199/CNTs coating. Finally, this novel enrichment method was successfully applied for the noninvasive analysis of trace ethylene, methanol, and ethanol from fruit samples with relatively high humidity. The low detection limit was 0.016 μg/L for ethylene. It was satisfactory that trace ethylene could be actually detected from fruit samples by this noninvasive method. Good recoveries of spiked grape, wampee, blueberry, and durian husk samples were obtained in the range of 90.0-114%, 79.4-88.6%, 78.5-86.8%, and 85.2-105% with the corresponding relative standard deviations of 4.8-9.8%, 6.9-8.9%, 3.8-8.1%, and 9.3-10.5% (n = 3), respectively.

  14. High efficiency production and genomic in situ hybridization analysis of Brassica aneuploids and homozygous plants

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Interspecific and intergeneric hybridizations have been widely used in plant genetics and breeding to construct stocks for genetic analysis and to introduce into crops the desirable traits and genes from their relatives. The intergeneric crosses between Brassica juncea (L.) Czern. & Coss., B. carinata A. Braun and Orychophragmus violaceus (L.) O. E. Schulz were made and the plants produced were subjected to genomic in situ hybridization analysis. The mixoploids from the cross with B. juncea were divided into three groups. The partially fertile mixoploids in the first group (2n = 36-42) mainly contained the somatic cells and pollen mother cells (PMCs) with the 36 chromosomes of B. juncea and additional chromosomes of O. violaceus. The mixoploids (2n = 30-36) in the second and third groups were morphologically quite similar to the mother plants B. juncea and showed nearly normal fertility. The plants in the second group produced the majority of PMCs (2n = 36) with their chromosomes paired and segregated normally, but 1-4 pairs of the O. violaceus chromosomes were included in some PMCs. The plants in the third group produced only PMCs with the 36 B. juncea chromosomes, which were paired and segregated normally. The mixoploids (2n = 29-34) from the cross with B. carinata produced the majority of PMCs (2n = 34) with normal chromosome pairing and segregation, but some plants had some PMCs with 1-3 pairs of chromosomes from O. violaceus and other plants had only PMCs with the B. carinata chromosomes. The Brassica homozygous plants and aneuploids with complete or partial chromosome complements of Brassica parents and various numbers of O. violaceus chromosomes were derived from these progeny plants. The results in this study provided the molecular cytogenetic evidence for the separation of parental genomes which was previously proposed to occur in the hybridizations of these two genera.

  15. Genetic molecular analysis of Coffea arabica (Rubiaceae hybrids using SRAP markers

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    Manoj Kumar Mishra

    2011-06-01

    Full Text Available In Coffea arabica (arabica coffee, the phenotypic as well as genetic variability has been found low because of the narrow genetic basis and self fertile nature of the species. Because of high similarity in phenotypic appearance among the majority of arabica collections, selection of parental lines for inter-varietals hybridization and identification of resultant hybrids at an early stage of plant growth is difficult. DNA markers are known to be reliable in identifying closely related cultivars and hybrids. Sequence Related Amplified Polymorphism (SRAP is a new molecular marker technology developed based on PCR. In this paper, sixty arabica-hybrid progenies belonging to six crosses were analyzed using 31 highly polymorphic SRAP markers. The analysis revealed seven types of SRAP marker profiles which are useful in discriminating the parents and hybrids. The number of bands amplified per primer pair ranges from 6.13 to 8.58 with average number of seven bands. Among six hybrid combinations, percentage of bands shared between hybrids and their parents ranged from 66.29% to 85.71% with polymorphic bands varied from 27.64% to 60.0%. Percentage of hybrid specific fragments obtained in various hybrid combinations ranged from 0.71% to 10.86% and ascribed to the consequence of meiotic recombination. Based on the similarity index calculation, it was observed that F1 hybrids share maximum number of bands with the female parent compared to male parent. The results obtained in the present study revealed the effectiveness of SRAP technique in cultivar identification and hybrid analysis in this coffee species. Rev. Biol. Trop. 59 (2: 607-617. Epub 2011 June 01.En Coffea arabica (café arabica, el fenotipo y la variabilidad genética son bajos debido a la estrecha base genética y la autofecundación de la especie. Por su alta similitud fenotípica entre la mayoría de las colecciones de arábica, la selección de líneas parentales para hibridación entre

  16. Analysis of [Gossypium capitis-viridis × (G.hirsutum × G.australe)2] Trispecific Hybrid and Selected Characteristics.

    Science.gov (United States)

    Chen, Di; Wu, Yuxiang; Zhang, Xiling; Li, Fuguang

    2015-01-01

    Speciation is always a contentious and challenging issue following with the presence of gene flow. In Gossypium, there are many valuable resources and wild diploid cotton especially C and B genome species possess some excellent traits which cultivated cotton always lacks. In order to explore character transferring rule from wild cotton to upland tetraploid cotton, the [G. capitis-viridis × (G. hirsutum × G. australe)2] triple hybrid was synthesized by interspecies hybridization and chromosome doubling. Morphology comparisons were measured among this hybrid and its parents. It showed that trispecific hybrid F1 had some intermediate morphological characters like leaf style between its parents and some different characters from its parents, like crawl growth characteristics and two kind flower color. It is highly resistant to insects comparing with other cotton species by four year field investigation. By cytogenetic analysis, triple hybrid was further confirmed by meiosis behavior of pollen mother cells. Comparing with regular meiosis of its three parents, it was distinguished by the occurrence of polyads with various numbers of unbalanced microspores and finally generating various abnormal pollen grains. All this phenomenon results in the sterility of this hybrid. This hybrid was further identified by SSR marker from DNA molecular level. It showed that 98 selected polymorphism primers amplified effective bands in this hybrids and its parents. The genetic proportion of three parents in this hybrid is 47.8% from G. hirsutum, 14.3% from G. australe, 7.0% from G. capitis-viridis, and 30.9% recombination bands respectively. It was testified that wild genetic material has been transferred into cultivated cotton and this new germplasm can be incorporated into cotton breeding program.

  17. Analysis of [Gossypium capitis-viridis × (G.hirsutum × G.australe2] Trispecific Hybrid and Selected Characteristics.

    Directory of Open Access Journals (Sweden)

    Di Chen

    Full Text Available Speciation is always a contentious and challenging issue following with the presence of gene flow. In Gossypium, there are many valuable resources and wild diploid cotton especially C and B genome species possess some excellent traits which cultivated cotton always lacks. In order to explore character transferring rule from wild cotton to upland tetraploid cotton, the [G. capitis-viridis × (G. hirsutum × G. australe2] triple hybrid was synthesized by interspecies hybridization and chromosome doubling. Morphology comparisons were measured among this hybrid and its parents. It showed that trispecific hybrid F1 had some intermediate morphological characters like leaf style between its parents and some different characters from its parents, like crawl growth characteristics and two kind flower color. It is highly resistant to insects comparing with other cotton species by four year field investigation. By cytogenetic analysis, triple hybrid was further confirmed by meiosis behavior of pollen mother cells. Comparing with regular meiosis of its three parents, it was distinguished by the occurrence of polyads with various numbers of unbalanced microspores and finally generating various abnormal pollen grains. All this phenomenon results in the sterility of this hybrid. This hybrid was further identified by SSR marker from DNA molecular level. It showed that 98 selected polymorphism primers amplified effective bands in this hybrids and its parents. The genetic proportion of three parents in this hybrid is 47.8% from G. hirsutum, 14.3% from G. australe, 7.0% from G. capitis-viridis, and 30.9% recombination bands respectively. It was testified that wild genetic material has been transferred into cultivated cotton and this new germplasm can be incorporated into cotton breeding program.

  18. Large Improvements in MS/MS Based Peptide Identification Rates using a Hybrid Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cannon, William R.; Rawlins, Mitchell M.; Baxter, Douglas J.; Callister, Stephen J.; Lipton, Mary S.; Bryant, Donald A.

    2011-05-06

    We have developed a hybrid method for identifying peptides from global proteomics studies that significantly increases sensitivity and specificity in matching peptides to tandem mass spectra using database searches. The method increased the number of spectra that can be assigned to a peptide in a global proteomics study by 57-147% at an estimated false discovery rate of 5%, with clear room for even greater improvements. The approach combines the general utility of using consensus model spectra typical of database search methods1-3 with the accuracy of the intensity information contained in spectral libraries4-6. This hybrid approach is made possible by recent developments that elucidated the statistical framework common to both data analysis and statistical thermodynamics, resulting in a chemically inspired approach to incorporating fragment intensity information into both database searches and spectral library searches. We applied this approach to proteomics analysis of Synechococcus sp. PCC 7002, a cyanobacterium that is a model organism for studies of photosynthetic carbon fixation and biofuels development. The increased specificity and sensitivity of this approach allowed us to identify many more peptides involved in the processes important for photoautotrophic growth.

  19. Hybrid sentiment analysis utilizing multiple indicators to determine temporal shifts of opinion in OSNs

    Science.gov (United States)

    White, Joshua S.; Hall, Robert T.; Fields, Jeremy; White, Holly M.

    2016-05-01

    Utilization of traditional sentiment analysis for predicting the outcome of an event on a social network depends on: precise understanding of what topics relate to the event, selective elimination of trends that don't fit, and in most cases, expert knowledge of major players of the event. Sentiment analysis has traditionally taken one of two approaches to derive a quantitative value from qualitative text. These approaches include the bag of words model", and the usage of "NLP" to attempt a real understanding of the text. Each of these methods yield very similar accuracy results with the exception of some special use cases. To do so, however, they both impose a large computational burden on the analytic system. Newer approaches have this same problem. No matter what approach is used, SA typically caps out around 80% in accuracy. However, accuracy is the result of both polarity and degree of polarity, nothing else. In this paper we present a method for hybridizing traditional SA methods to better determine shifts in opinion over time within social networks. This hybridization process involves augmenting traditional SA measurements with contextual understanding, and knowledge about writers' demographics. Our goal is to not only to improve accuracy, but to do so with minimal impact to computation requirements.

  20. A Mathematical and Numerical Model for the Analysis of Hybrid Rocket Motors

    Directory of Open Access Journals (Sweden)

    Florin MINGIREANU

    2011-12-01

    Full Text Available The hybrid rocket motors (HRM use a two-phase propellant system. This offers some remarkable advantages but also arises some difficulties like the neutralization of their instabilities. The non-acoustic combustion instabilities are high-amplitude pressure oscillations that have too low frequencies to be associated with acoustics. Acoustic type combustion instabilities are self-excited oscillations generated by the interaction between acoustic waves and combustion. The goal of the present work is to develop a simplified model of the coupling of the hybrid combustion process with the complete unsteady flow, starting from the combustion port and ending with the nozzle. This model must be useful for transient and stability analysis and also for scaling of HRMs. The numerical results obtained with our model show a good agreement with published experimental and numerical results. The computational and stability analysis models developed in this work are simple, computationally efficient and offer the advantage of taking into account a large number of functional and constructive parameters that are used by the engineers.

  1. Quantitative data analysis methods for bead-based DNA hybridization assays using generic flow cytometry platforms.

    Science.gov (United States)

    Corrie, S R; Lawrie, G A; Battersby, B J; Ford, K; Rühmann, A; Koehler, K; Sabath, D E; Trau, M

    2008-05-01

    Bead-based assays are in demand for rapid genomic and proteomic assays for both research and clinical purposes. Standard quantitative procedures addressing raw data quality and analysis are required to ensure the data are consistent and reproducible across laboratories independent of flow platform. Quantitative procedures have been introduced spanning raw histogram analysis through to absolute target quantitation. These included models developed to estimate the absolute number of sample molecules bound per bead (Langmuir isotherm), relative quantitative comparisons (two-sided t-tests), and statistical analyses investigating the quality of raw fluorescence data. The absolute target quantitation method revealed a concentration range (below probe saturation) of Cy5-labeled synthetic cytokeratin 19 (K19) RNA of c.a. 1 x 10(4) to 500 x 10(4) molecules/bead, with a binding constant of c.a. 1.6 nM. Raw hybridization frequency histograms were observed to be highly reproducible across 10 triplex assay replicates and only three assay replicates were required to distinguish overlapping peaks representing small sequence mismatches. This study provides a quantitative scheme for determining the absolute target concentration in nucleic acid hybridization reactions and the equilibrium binding constants for individual probe/target pairs. It is envisaged that such studies will form the basis of standard analytical procedures for bead-based cytometry assays to ensure reproducibility in inter- and intra-platform comparisons of data between laboratories. (c) 2008 International Society for Advancement of Cytometry.

  2. Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri

    Directory of Open Access Journals (Sweden)

    Malone John H

    2008-03-01

    Full Text Available Abstract Background Interspecific hybrids of frogs of the genus Xenopus result in sterile hybrid males and fertile hybrid females. Previous work has demonstrated a dramatic asymmetrical pattern of misexpression in hybrid males compared to the two parental species with relatively few genes misexpressed in comparisons of hybrids and the maternal species (X. laevis and dramatically more genes misexpressed in hybrids compared to the paternal species (X. muelleri. In this work, we examine the gene expression pattern in hybrid females of X. laevis × X. muelleri to determine if this asymmetrical pattern of expression also occurs in hybrid females. Results We find a similar pattern of asymmetry in expression compared to males in that there were more genes differentially expressed between hybrids and X. muelleri compared to hybrids and X. laevis. We also found a dramatic increase in the number of misexpressed genes with hybrid females having about 20 times more genes misexpressed in ovaries compared to testes of hybrid males and therefore the match between phenotype and expression pattern is not supported. Conclusion We discuss these intriguing findings in the context of reproductive isolation and suggest that divergence in female expression may be involved in sterility of hybrid males due to the inherent sensitivity of spermatogenesis as defined by the faster male evolution hypothesis for Haldane's rule.

  3. Hybrid Microfluidic Platform for Multifactorial Analysis Based on Electrical Impedance, Refractometry, Optical Absorption and Fluorescence

    Directory of Open Access Journals (Sweden)

    Fábio M. Pereira

    2016-10-01

    Full Text Available This paper describes the development of a novel microfluidic platform for multifactorial analysis integrating four label-free detection methods: electrical impedance, refractometry, optical absorption and fluorescence. We present the rationale for the design and the details of the microfabrication of this multifactorial hybrid microfluidic chip. The structure of the platform consists of a three-dimensionally patterned polydimethylsiloxane top part attached to a bottom SU-8 epoxy-based negative photoresist part, where microelectrodes and optical fibers are incorporated to enable impedance and optical analysis. As a proof of concept, the chip functions have been tested and explored, enabling a diversity of applications: (i impedance-based identification of the size of micro beads, as well as counting and distinguishing of erythrocytes by their volume or membrane properties; (ii simultaneous determination of the refractive index and optical absorption properties of solutions; and (iii fluorescence-based bead counting.

  4. Optimization of process parameters in drilling of fibre hybrid composite using Taguchi and grey relational analysis

    Science.gov (United States)

    Vijaya Ramnath, B.; Sharavanan, S.; Jeykrishnan, J.

    2017-03-01

    Nowadays quality plays a vital role in all the products. Hence, the development in manufacturing process focuses on the fabrication of composite with high dimensional accuracy and also incurring low manufacturing cost. In this work, an investigation on machining parameters has been performed on jute-flax hybrid composite. Here, the two important responses characteristics like surface roughness and material removal rate are optimized by employing 3 machining input parameters. The input variables considered are drill bit diameter, spindle speed and feed rate. Machining is done on CNC vertical drilling machine at different levels of drilling parameters. Taguchi’s L16 orthogonal array is used for optimizing individual tool parameters. Analysis Of Variance is used to find the significance of individual parameters. The simultaneous optimization of the process parameters is done by grey relational analysis. The results of this investigation shows that, spindle speed and drill bit diameter have most effect on material removal rate and surface roughness followed by feed rate.

  5. A new damage diagnosis approach for NC machine tools based on hybrid Stationary subspace analysis

    Science.gov (United States)

    Gao, Chen; Zhou, Yuqing; Ren, Yan

    2017-05-01

    This paper focused on the damage diagnosis for NC machine tools and put forward a damage diagnosis method based on hybrid Stationary subspace analysis (SSA), for improving the accuracy and visibility of damage identification. First, the observed single sensor signal was reconstructed to multi-dimensional signals by the phase space reconstruction technique, as the inputs of SSA. SSA method was introduced to separate the reconstructed data into stationary components and non-stationary components without the need for independency and prior information of the origin signals. Subsequently, the selected non-stationary components were analysed for training LS-SVM (Least Squares Support Vector Machine) classifier model, in which several statistic parameters in the time and frequency domains were exacted as the sample of LS-SVM. An empirical analysis in NC milling machine tools is developed, and the result shows high accuracy of the proposed approach.

  6. Hybridization of DCT and SVD in the Implementation and Performance Analysis of Video Watermarking

    Directory of Open Access Journals (Sweden)

    Ved Vyas Dwivedi

    2012-06-01

    Full Text Available In this Paper, We worked and documented the implementation and performance analysis of digital video watermarking that uses the hybrid features of two of the most powerful transform domain processing of the video and fundamentals of the linear algebra. We have taken into the account fundamentals of Discrete Cosine Transform and Singular Value Decomposition for the development of the proposed algorithm. We first used the Singular Value Decomposition and then used the singular values for the insertion of the message behind the video. Finally we used two of the visual quality matrices for the analysis purpose. We also applied various attacks on the video and found the proposed scheme more robust.

  7. Unified performance analysis of hybrid-ARQ with incremental redundancy over free-space optical channels

    KAUST Repository

    Zedini, Emna

    2014-09-01

    In this paper, we carry out a unified performance analysis of hybrid automatic repeat request (HARQ) with incremental redundancy (IR) from an information theoretic perspective over a point-to-point free-space optical (FSO) system. First, we introduce a novel unified expression for the distribution of a single FSO link modeled by the Gamma fading that accounts for pointing errors subject to both types of detection techniques at the receiver side (i.e. heterodyne detection and intensity modulation with direct detection (IM/DD)). Then, we provide analytical expressions for the outage probability, the average number of transmissions, and the average transmission rate for HARQ with IR, assuming a maximum number of rounds for the HARQ protocol. In our study, the communication rate per HARQ round is constant. Our analysis demonstrates the importance of HARQ in improving the performance and reliability of FSO communication systems. All the given results are verified via computer-based Monte-Carlo simulations.

  8. Comparative Analysis on Rice Plant Type of Two Super Hybrids and Shanyou63

    Institute of Scientific and Technical Information of China (English)

    LU Chuan-gen; ZOU Jiang-shi

    2003-01-01

    The characteristics of plant type and physiological indices for photosynthesis were analyzedusing two super hybrid rices, Liangyoupeijiu and LiangyouE32 as materials, and an indica hybrid, Shan-you63 as a control. Based on the present analysis and various theories and breeding practices on rice planttype, a model of plant ideotype for super hybrid rice (indica) in the lower reaches of Yangtze River Valleywas proposed. This was: a length of 35 - 40 cm for top leaf with a width of 2 cm, and that of 50 - 55 cmand 55 - 60 crm, respectively, for the second and third leaves from top, meanwhile, having a leaf angle of5°, 10° and 15° respectively, and a curvature of 1 - 1.5 cm-1 for the leaf face at heading stage; the upper-most three leaves keeping their activities for as long as 70 d, which could lead a LAI of 3 at full ripeness;loose plant type with thin (SLW=2.5- 3 gcm-2 , dry weight) and curve-slant leaves during early growingstage, and compact plant type by thick (SLW = 4 - 5 gcm-2 ) and erect leaves during the middle and lategrowing stages; with a coefficient of light extinction of 0.3 - 0.4, which allowed for an optimal LAI high of8 - 10 during the middle growth period; plant height of 110 -120 cm, with 2 -4 cm basal internode and along uppermost internode occupying 45 % of total stem length; 25 - 28 cm panicle with 8 - 10 spikelets percentimeter showing bend-type in ripening; a rich chlorophyll which led to a high net photosynthetic rate,and tolerance to light shading and photooxidation which is of benefit to increasing the adaptability to varyinglight conditions.

  9. Molecular Cytogenetic Analysis of Spontaneous Interspecific Hybrid Between Oryza sativa and Oryza minuta

    Institute of Scientific and Technical Information of China (English)

    YI Chuan-deng; CHENG Xu; WANG Bei-bei; LIANG Guo-hua; GONG Zhi-yun; TANG Shu-zhu; GU Ming-hong

    2008-01-01

    Genomic in situ hybridization (GISH) is a powerful tool to characterize parental chromosomes in interspecific hybrids, including the behaviour of autosynapsis and chromosome paidng. It was used to distinguish the chromosomes of Oryza sativa from wild species in a spontaneous interspecific hybdd and to investigate the chromosome pairing at metaphase I in meiosis of the hybdd in this study. The hybrid was a triploid with 36 chromosomes according to the chromosome nurnber investigated in mitosis of root tips. During metaphase I of meiosis in the hybrid, less chromosome pairing was observed and most of the chromosomes existed as univalent. Based on GISH and FISH (Fluorescent in situ hybridization) analyses, the chromosomes of the hybrid were composed of genomes A, B and C. Thus, it was believed that the hybrid was the result of natural hybridization between cultivated rice and wild species O. minuta which was planted in experimental fields.

  10. Array-based comparative genomic hybridization is more informative than conventional karyotyping and fluorescence in situ hybridization in the analysis of first-trimester spontaneous abortion

    Directory of Open Access Journals (Sweden)

    Gao Jinsong

    2012-07-01

    Full Text Available Abstract Background Array-based comparative genomic hybridization (aCGH is a new technique for detecting submicroscopic deletions and duplications, and can overcome many of the limitations associated with classic cytogenetic analysis. However, its clinical use in spontaneous abortion needs comprehensive evaluation. We used aCGH to investigate chromosomal imbalances in 100 spontaneous abortions and compared the results with G-banding karyotyping and fluorescence in situ hybridization (FISH. Inconsistent results were verified by quantitative fluorescence PCR. Results Abnormalities were detected in 61 cases. aCGH achieved the highest detection rate (93.4%, 57/61 compared with traditional karyotyping (77%, 47/61 and FISH analysis (68.9%, 42/61. aCGH identified all chromosome abnormalities reported by traditional karyotyping and interphase FISH analysis, with the exception of four triploids. It also detected three additional aneuploidy cases in 37 specimens with ‘normal’ karyotypes, one mosaicism and 10 abnormalities in 14 specimens that failed to grow in vitro. Conclusions aCGH analysis circumvents many limitations in traditional karyotyping or FISH. The accuracy and efficiency of aCGH in spontaneous abortions highlights its clinical usefulness for the future. As aborted tissues have the potential to be contaminated with maternal cells, the threshold value of detection in aCGH should be lowered to avoid false negatives.

  11. Analysis and design of permanent magnet biased magnetic bearing based on hybrid factor

    Directory of Open Access Journals (Sweden)

    Jinji Sun

    2016-03-01

    Full Text Available In this article, hybrid factor is proposed for hybrid magnetic bearing. The hybrid factor is defined as the ratio of the force produced by the permanent magnet and the forces produced by the permanent magnet and current in hybrid magnetic bearing. It is deduced from a certain radial hybrid magnetic bearing using its important parameters such as the current stiffness and displacement stiffness at first and then the dynamic model of magnetically suspended rotor system is established. The relationship between structural parameters and control system parameters is analyzed based on the hybrid factor. Some influencing factors of hybrid factor in hybrid magnetic bearing, such as the size of the permanent magnet, length of air gap, and area of the stator poles, are analyzed in this article. It can be concluded that larger hybrid factor can be caused by the smaller power loss according to the definition of hybrid factor mentioned above. Meanwhile, the hybrid factor has a maximum value, which is related to control system parameters such as proportional factor expect for structural parameters. Finally, the design steps of parameters of hybrid magnetic bearing can be concluded.

  12. Analysis of Hybrid-Electric Propulsion System Designs for Small Unmanned Aircraft Systems

    Science.gov (United States)

    2010-03-01

    arrival of the Insight, nearly every major automotive manufacturer has released its own hybrid model. The Toyota Prius , released to the US in 2001, has...dominated the hybrid marketplace with US sales topping 1,000,000 in March 2009.17 The Prius features a power-split hybrid system enabling use of an

  13. Design tradeoff studies and sensitivity analysis. Appendices B1-B4. [HYBRID

    Energy Technology Data Exchange (ETDEWEB)

    1979-05-25

    These four appendices to the report on the Near-Term Hybrid Vehicle (NTHV) report contain information on: HYBRID computer program documentation; material substitution study for advanced hybrid vehicles; NTHV market potential; battery compartment weight distribution; and vehicle handling dynamics. (LCL)

  14. Experimental, numerical, and analytical studies on the seismic response of steel-plate concrete (SC) composite shear walls

    Science.gov (United States)

    Epackachi, Siamak

    The seismic performance of rectangular steel-plate concrete (SC) composite shear walls is assessed for application to buildings and mission-critical infrastructure. The SC walls considered in this study were composed of two steel faceplates and infill concrete. The steel faceplates were connected together and to the infill concrete using tie rods and headed studs, respectively. The research focused on the in-plane behavior of flexure- and flexure-shear-critical SC walls. An experimental program was executed in the NEES laboratory at the University at Buffalo and was followed by numerical and analytical studies. In the experimental program, four large-size specimens were tested under displacement-controlled cyclic loading. The design variables considered in the testing program included wall thickness, reinforcement ratio, and slenderness ratio. The aspect ratio (height-to-length) of the four walls was 1.0. Each SC wall was installed on top of a re-usable foundation block. A bolted baseplate to RC foundation connection was used for all four walls. The walls were identified to be flexure- and flexure-shear critical. The progression of damage in the four walls was identical, namely, cracking and crushing of the infill concrete at the toes of the walls, outward buckling and yielding of the steel faceplates near the base of the wall, and tearing of the faceplates at their junctions with the baseplate. A robust finite element model was developed in LS-DYNA for nonlinear cyclic analysis of the flexure- and flexure-shear-critical SC walls. The DYNA model was validated using the results of the cyclic tests of the four SC walls. The validated and benchmarked models were then used to conduct a parametric study, which investigated the effects of wall aspect ratio, reinforcement ratio, wall thickness, and uniaxial concrete compressive strength on the in-plane response of SC walls. Simplified analytical models, suitable for preliminary analysis and design of SC walls, were

  15. Performance Analysis of High-Speed Deep/Shallow Recessed Hybrid Bearing

    Directory of Open Access Journals (Sweden)

    Lei Wang

    2013-01-01

    Full Text Available The present paper proposes a theoretical analysis of the performance of deep/shallow recessed hybrid bearing. It is intended that, on the basis of the numerical results drawn from this study, appropriate shallow recess depth and width can be determined for use in the bearing design process. By adopting bulk flow theory, the turbulent Reynolds equation and energy equation are modified and solved numerically including concentrated inertia effects at the recess edge with different depth and width of shallow recess. The results indicate that the load capacity, drag torque increases as the depth of shallow recess is shallower and the width ratio (half angle of deep recess versus half angle of shallow recess is smaller. In contrast, the flow rate decreases as the depth of shallow recess is shallower and the width ratio is smaller. Nevertheless, the appropriate design of the depth and width of shallow recess might well induce the performance of high-speed deep/shallow recessed hybrid bearing.

  16. Techno-economic Analysis of a Wind-Diesel Hybrid Power System in the South Algeria

    Directory of Open Access Journals (Sweden)

    Khaireddine Allali

    2015-07-01

    Full Text Available The electrical energy is often produced with the help of diesel generators in isolated areas in the Saharan region. While the latter requiring relatively little investment because is generally expensive to exploit due to the transportation to remote areas adds extra cost, significant fuel consumption and relatively high maintenance cost, etc. Moreover, the electricity production by the diesel is ineffective, presents significant environmental risks. But these isolated areas have significant wind energy potential; which is good position for the exploitation of clean and sustainable wind energy. The use of wind-diesel power system is widely recommended especially to reduce fuel consumption and in this way to reduce system operating costs and environmental impact. The subject of this paper is to present the techno-economic analysis of a wind-diesel hybrid power system. In this context, the contribution envisaged with this research is to collaborate on the optimal design of a hybrid power system including a wind turbine generator, a diesel generator and an energy storage system for powering a continuous way an isolated site in the South Algerian installed power of 120 kW.This system has a high control strategy for the management of different power sources (wind, diesel, battery that depending to weather conditions, especially wind speed values and the power demanded by the consumer load.

  17. Analysis of PV-FC Hybrid System Operation Considering Sale Electricity

    Directory of Open Access Journals (Sweden)

    Amirali Shahkoomahalli

    2013-06-01

    Full Text Available This paper presents a hybrid power generation system modeling and simulation with the objective of electricity sale to distribution network (DN which consists of photovoltaic (PV module, proton exchange membrane (PEM fuel cell (FC, hydrogen storage tank (HST and electrolyzer (EL.Since last researches in optimal FC and PV application aimed in power electronic approach, In this paper the application between FC and PV is considered with the aim of maximizing profit gained due to electricity sale revenue to DN. The revenue from electricity sale to DN considering electricity price in low load, shoulder load and peak load hours is considered as the system profit. Also in a sensitivity analysis the impact of technical parameters of hybrid system components is investigated on system profit. The results showed that the system saves the electricity by hydrogen storage in HST in low load hours and sale it with more prices in shoulder load hours to DN. Also the obtained results show that several technical parameters of PV and PEM FC have considerable impact on system operation and profit.

  18. Cycle Analysis of Micro Gas Turbine-Molten Carbonate Fuel Cell Hybrid System

    Science.gov (United States)

    Kimijima, Shinji; Kasagi, Nobuhide

    A hybrid system based on a micro gas turbine (µGT) and a high-temperature fuel cell, i.e., molten carbonate fuel cell (MCFC) or solid oxide fuel cell (SOFC), is expected to achieve a much higher efficiency than conventional distributed power generation systems. In this study, a cycle analysis method and the performance evaluation of a µGT-MCFC hybrid system, of which the power output is 30kW, are investigated to clarify its feasibility. We developed a general design strategy in which a low fuel input to a combustor and higher MCFC operating temperature result in a high power generation efficiency. A high recuperator temperature effectiveness and a moderate steam-carbon ratio are the requirements for obtaining a high material strength in a turbine. In addition, by employing a combustor for complete oxidation of MCFC effluents without additional fuel input, i.e., a catalytic combustor, the power generation efficiency of a µGT-MCFC is achieved at over 60%(LHV).

  19. Multivariable analysis of effects of various methods of magnesium application of LG 2244 maize hybrid

    Directory of Open Access Journals (Sweden)

    Jan Bocianowski

    2013-03-01

    Full Text Available The paper presents a multivariable approach to the estimation of variability for quantitative traits after using the seven methods of magnesium application of the “stay-green” type of maize (Zea mays L. hybrid. The 13 characteristics of LG 2244 hybrid were under consideration in three years (2006-2008: grain yield, moisture of grain, 1000 grain yield, dry matter of a single plant, dry matter yield, uptake of N, uptake of P, uptake of K, uptake of Mg, uptake of Ca, chlorophyll a, chlorophyll b and chlorophyll a+b content. The obtained results were computed with statistical multivariable methods of application. Canonical variable analysis (in each year independent has proved to be an effective tool for clear assessing of differences among the studied methods of magnesium application. The most diverse methods were: C and E (in 2006, A and F (in 2007, and B as G (in 2008. The most similar methods (in respect of 13 traits simultaneously were: B and C (in 2006, D and E (in 2007, and C and E (in 2008. Mahalanobis’ distances between methods of magnesium application in individual years of the study were not significantly correlated.

  20. Time-series analysis with a hybrid Box-Jenkins ARIMA and neural network model

    Institute of Scientific and Technical Information of China (English)

    Dilli R Aryal; WANG Yao-wu(王要武)

    2004-01-01

    Time-series analysis is important to a wide range of disciplines transcending both the physical and social sciences for proactive policy decisions. Statistical models have sound theoretical basis and have been successfully used in a number of problem domains in time series forecasting. Due to power and flexibility, Box-Jenkins ARIMA model has gained enormous popularity in many areas and research practice for the last three decades.More recently, the neural networks have been shown to be a promising alternative tool for modeling and forecasting owing to their ability to capture the nonlinearity in the data. However, despite the popularity and the superiority of ARIMA and ANN models, the empirical forecasting performance has been rather mixed so that no single method is best in every situation. In this study, a hybrid ARIMA and neural networks model to time series forecasting is proposed. The basic idea behind the model combination is to use each model's unique features to capture different patterns in the data. With three real data sets, empirical results evidently show that the hybrid model outperforms ARIMA and ANN model noticeably in terms of forecasting accuracy used in isolation.

  1. Finite element analysis of hybrid energy harvesting of piezoelectric and electromagnetic

    Directory of Open Access Journals (Sweden)

    Muhammad Yazid Muhammad Ammar Faris

    2017-01-01

    Full Text Available Harvesting energy from ambient vibrations is a highly required method because of the wide range of available sources that produce vibration energy application from industrial machinery to human motion application. In this paper, the implementation of harvesting energy from two technologies to form a hybrid energy harvester system was analyzed. These two technologies involve the piezoelectric harvesting energy and the electromagnetic harvesting energy. A finite element model was developed using the Ansys software with the harmonic analysis solver to analyze and examine hybrid harvesting energy system. Both power output generated from the magnet and the piezoelectric is then combined to form one unit of energy. Further, it was found that the result shows the system generate the maximum power output of 14.85 μW from 100 Hz, 4.905 m/s2, and 0.6 cm3 for resonance frequency, acceleration, and the volume respectively from the optimal energy harvester design. Normalized Power Density (NPD result of 10.29 kgs/m3 comparable with other literature also can be used in energy harvesting system for vibration application.

  2. Optimization and Static Stress Analysis of Hybrid Fiber Reinforced Composite Leaf Spring

    Directory of Open Access Journals (Sweden)

    Luay Muhammed Ali Ismaeel

    2015-01-01

    Full Text Available A monofiber reinforced composite leaf spring is proposed as an alternative to the typical steel one as it is characterized by high strength-to-weight ratio. Different reinforcing schemes are suggested to fabricate the leaf spring. The composite and the typical steel leaf springs are subjected to the same working conditions. A weight saving of about more than 60% can be achieved while maintaining the strength for the structures under consideration. The objective of the present study was to replace material for leaf spring. This study suggests various materials of hybrid fiber reinforced plastics (HFRP. Also the effects of shear moduli of the fibers, matrices, and the composites on the composites performance and responses are discussed. The results and behaviors of each are compared with each other and verified by comparison with analytical solution; a good convergence is found between them. The elastic properties of the hybrid composites are calculated using rules of mixtures and Halpin-Tsi equation through the software of MATLAB v-7. The problem is also analyzed by the technique of finite element analysis (FEA through the software of ANSYS v-14. An element modeling was done for every leaf with eight-node 3D brick element (SOLID185 3D 8-Node Structural Solid.

  3. Hybrid motion sensing and experimental modal analysis using collocated smartphone camera and accelerometers

    Science.gov (United States)

    Ozer, Ekin; Feng, Dongming; Feng, Maria Q.

    2017-10-01

    State-of-the-art multisensory technologies and heterogeneous sensor networks propose a wide range of response measurement opportunities for structural health monitoring (SHM). Measuring and fusing different physical quantities in terms of structural vibrations can provide alternative acquisition methods and improve the quality of the modal testing results. In this study, a recently introduced SHM concept, SHM with smartphones, is focused to utilize multisensory smartphone features for a hybridized structural vibration response measurement framework. Based on vibration testing of a small-scale multistory laboratory model, displacement and acceleration responses are monitored using two different smartphone sensors, an embedded camera and accelerometer, respectively. Double-integration or differentiation among different measurement types is performed to combine multisensory measurements on a comparative basis. In addition, distributed sensor signals from collocated devices are processed for modal identification, and performance of smartphone-based sensing platforms are tested under different configuration scenarios and heterogeneity levels. The results of these tests show a novel and successful implementation of a hybrid motion sensing platform through multiple sensor type and device integration. Despite the heterogeneity of motion data obtained from different smartphone devices and technologies, it is shown that multisensory response measurements can be blended for experimental modal analysis. Getting benefit from the accessibility of smartphone technology, similar smartphone-based dynamic testing methodologies can provide innovative SHM solutions with mobile, programmable, and cost-free interfaces.

  4. An exergetic/energetic/economic analysis of three hydrogen production processes - Electrolysis, hybrid, and thermochemical

    Science.gov (United States)

    Funk, J. E.; Eisermann, W.

    This paper presents the results of a combined first and second law analysis, along with capital and operating costs, for hydrogen production from water by means of electrolytic, hybrid, and thermochemical processes. The processes are SPE and Lurgi electrolysis with light water reactor power generation and sulfur cycle hybrid, thermochemical and SPE electrolysis with a very high temperature reactor primary energy source. Energy and Exergy (2nd law) flow diagrams for the process are shown along with the location and magnitude of the process irreversibilities. The overall process thermal (1st law) efficiencies vary from 25 to 51% and the exergetic (2nd law) efficiencies, referred to the fuel for the primary energy source, vary from 22 to 45%. Capital and operating costs, escalated to 1979 dollars, are shown for each process for both the primary energy source and the hydrogen production plant. All costs were taken from information available in the open literature and are for a plant capacity of 100 x 10 to the 6th SCF/day. Production costs vary from 10 to 18 $/GJ, based on the higher heating value of hydrogen, and are based on a 90% plant operating factor with a 21% annual charge on total capital costs.

  5. Hybrid Integration of Taguchi Parametric Design, Grey Relational Analysis, and Principal Component Analysis Optimization for Plastic Gear Production

    Directory of Open Access Journals (Sweden)

    Nik Mizamzul Mehat

    2014-01-01

    Full Text Available The identification of optimal processing parameters is an important practice in the plastic injection moulding industry because of the significant effect of such parameters on plastic part quality and cost. However, the optimization design of injection moulding process parameters can be difficult because more than one quality characteristic is used in the evaluation. This study systematically develops a hybrid optimization method for multiple quality characteristics by integrating the Taguchi parameter design, grey relational analysis, and principal component analysis. A plastic gear is used to demonstrate the efficiency and validity of the proposed hybrid optimization method in controlling all influential injection moulding processing parameters during plastic gear manufacturing. To minimize the shrinkage behaviour in tooth thickness, addendum circle, and dedendum circle of moulded gear, the optimal combination of different process parameters is determined. The case study demonstrates that the proposed optimization method can produce plastic-moulded gear with minimum shrinkage behaviour of 1.8%, 1.53%, and 2.42% in tooth thickness, addendum circle, and dedendum circle, respectively; these values are less than the values in the main experiment. Therefore, shrinkage-related defects that lead to severe failure in plastic gears can be effectively minimized while satisfying the demand of the global plastic gear industry.

  6. arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays

    Directory of Open Access Journals (Sweden)

    Moreau Yves

    2005-05-01

    Full Text Available Abstract Background The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has triggered and accelerated the use of several platforms for analysis of DNA copy number changes, amongst others microarray comparative genomic hybridization (arrayCGH. One of the challenges inherent to this new technology is the management and analysis of large numbers of data points generated in each individual experiment. Results We have developed arrayCGHbase, a comprehensive analysis platform for arrayCGH experiments consisting of a MIAME (Minimal Information About a Microarray Experiment supportive database using MySQL underlying a data mining web tool, to store, analyze, interpret, compare, and visualize arrayCGH results in a uniform and user-friendly format. Following its flexible design, arrayCGHbase is compatible with all existing and forthcoming arrayCGH platforms. Data can be exported in a multitude of formats, including BED files to map copy number information on the genome using the Ensembl or UCSC genome browser. Conclusion ArrayCGHbase is a web based and platform independent arrayCGH data analysis tool, that allows users to access the analysis suite through the internet or a local intranet after installation on a private server. ArrayCGHbase is available at http://medgen.ugent.be/arrayCGHbase/.

  7. A modified hybrid uncertain analysis method for dynamic response field of the LSOAAC with random and interval parameters

    Science.gov (United States)

    Zi, Bin; Zhou, Bin

    2016-07-01

    For the prediction of dynamic response field of the luffing system of an automobile crane (LSOAAC) with random and interval parameters, a hybrid uncertain model is introduced. In the hybrid uncertain model, the parameters with certain probability distribution are modeled as random variables, whereas, the parameters with lower and upper bounds are modeled as interval variables instead of given precise values. Based on the hybrid uncertain model, the hybrid uncertain dynamic response equilibrium equation, in which different random and interval parameters are simultaneously included in input and output terms, is constructed. Then a modified hybrid uncertain analysis method (MHUAM) is proposed. In the MHUAM, based on random interval perturbation method, the first-order Taylor series expansion and the first-order Neumann series, the dynamic response expression of the LSOAAC is developed. Moreover, the mathematical characteristics of extrema of bounds of dynamic response are determined by random interval moment method and monotonic analysis technique. Compared with the hybrid Monte Carlo method (HMCM) and interval perturbation method (IPM), numerical results show the feasibility and efficiency of the MHUAM for solving the hybrid LSOAAC problems. The effects of different uncertain models and parameters on the LSOAAC response field are also investigated deeply, and numerical results indicate that the impact made by the randomness in the thrust of the luffing cylinder F is larger than that made by the gravity of the weight in suspension Q . In addition, the impact made by the uncertainty in the displacement between the lower end of the lifting arm and the luffing cylinder a is larger than that made by the length of the lifting arm L .

  8. Rate-prediction structure complexity analysis for multi-view video coding using hybrid genetic algorithms

    Science.gov (United States)

    Liu, Yebin; Dai, Qionghai; You, Zhixiang; Xu, Wenli

    2007-01-01

    Efficient exploitation of the temporal and inter-view correlation is critical to multi-view video coding (MVC), and the key to it relies on the design of prediction chain structure according to the various pattern of correlations. In this paper, we propose a novel prediction structure model to design optimal MVC coding schemes along with tradeoff analysis in depth between compression efficiency and prediction structure complexity for certain standard functionalities. Focusing on the representation of the entire set of possible chain structures rather than certain typical ones, the proposed model can given efficient MVC schemes that adaptively vary with the requirements of structure complexity and video source characteristics (the number of views, the degrees of temporal and interview correlations). To handle large scale problem in model optimization, we deploy a hybrid genetic algorithm which yields satisfactory results shown in the simulations.

  9. Hybrid pigments resulting from several guest dyes onto γ-alumina host: A spectroscopic analysis

    Science.gov (United States)

    Pérez, Erik; Ibarra, Ilich A.; Guzmán, Ariel; Lima, Enrique

    2017-02-01

    The synthesis of hybrid pigments was made from combination of γ-Al2O3 and some organic chromophores such as carminic acid, alizarin, purpurin, curcumin, fluorescein and betacyanins. The γ-Al2O3 was obtained through sol-gel synthesis with 2-propanol and aluminium tri-sec-butoxide (ATB). This article presents some spectroscopic evidences related to the formation of aluminium complexes between coordinative unsaturated sites (CUS) of aluminium and some organic groups (carboxylic acid, quaternary ammonium and β-keto enol) present in the chromophores structure. The physicochemical properties upcoming from a spectroscopic analysis point out that these materials can be applied in the design of new materials with potential uses in artworks and in the field of cultural heritage.

  10. Aeromechanical stability analysis of a multirotor vehicle model representing a hybrid heavy lift airship (HHLA)

    Science.gov (United States)

    Venkatesan, C.; Friedmann, P. P.

    1984-01-01

    Hybrid Heavy Lift Airship (HHLA) is a proposed candidate vehicle aimed at providing heavy lift capability at low cost. This vehicle consists of a buoyant envelope attached to a supporting structure to which four rotor systems, taken from existing helicopters are attached. Nonlinear equations of motion capable of modelling the dynamics of this coupled multi-rotor/support frame/vehicle system have been developed. Using these equations of motion the aeroelastic and aeromechanical stability analysis is performed aimed at identifying potential instabilities which could occur for this type of vehicle. The coupling between various blade, supporting structure and rigid body modes is identified. Furthermore, the effects of changes in buoyancy ratio (Buoyant lift/total weight) on the dynamic characteristics of the vehicle are studied. The dynamic effects found are of considerable importance for the design of such vehicles. The analytical model developed is also useful for studying the aeromechanical stability of single rotor and tandem rotor coupled rotor/fuselage systems.

  11. Hybrid independent component analysis and twin support vector machine learning scheme for subtle gesture recognition.

    Science.gov (United States)

    Naik, Ganesh R; Kumar, Dinesh K; Jayadeva

    2010-10-01

    Myoelectric signal classification is one of the most difficult pattern recognition problems because large variations in surface electromyogram features usually exist. In the literature, attempts have been made to apply various pattern recognition methods to classify surface electromyography into components corresponding to the activities of different muscles, but this has not been very successful, as some muscles are bigger and more active than others. This results in dataset discrepancy during classification. Multicategory classification problems are usually solved by solving many, one-versus-rest binary classification tasks. These subtasks unsurprisingly involve unbalanced datasets. Consequently, we need a learning methodology that can take into account unbalanced datasets in addition to large variations in the distributions of patterns corresponding to different classes. Here, we attempt to address the above issues using hybrid features extracted from independent component analysis and twin support vector machine techniques.

  12. Performance Analysis of a Hybrid One-Sided Magnetic Exciter Mounted on a Piezoelectric Stack

    Directory of Open Access Journals (Sweden)

    A. Nandi

    2010-01-01

    Full Text Available The present work proposes a non-contact hybrid exciter especially useful for harmonic excitation of lightly damped structures/rotors. In the proposed exciter an electromagnet is placed on a piezoelectric stack and the extension of the piezoelectric stack is made almost equal to the displacement of the structure using a simple tracking control. This largely eliminates stiffness coupling between the structure/rotor and the exciter and non-linearity in the excitation force due to the vibration of the structure/rotor. The stiffness and inertia of the piezoelectric stack is considered in the analysis. A SIMULINK model of the combined structure and the exciter is developed for a full time-domain simulation of the excitation system.

  13. A NEW HYBRID FORECASTING ALGORITHM AND ITS APPLICATION IN ECONOMIC ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    There exists a great deal of periodic non-stationary processes in natural, social and economical phenomenon. It is very important to realize the dynamic analysis and real-time forecast within a period. In this letter, a wavelet-Kalman hybrid estimation and forecasting algorithm based on step-by-step filtering with the real-time and recursion property is put forward. It combines the advantages of Kalman filter and wavelet transform. Utilizing the information provided by multisensor effectively, this algorithm can realize not only real-time tracking and dynamic multi-step forecasting within a period, but also the dynamic forecasting between periods, and it has a great value to the system decision-making. Simulation results show that this algorithm is valuable.

  14. Finite-Element Analysis of Jute- and Coir-Fiber-Reinforced Hybrid Composite Multipanel Plates

    Science.gov (United States)

    Nirbhay, M.; Misra, R. K.; Dixit, A.

    2015-09-01

    Natural-fiber-reinforced polymer composite materials are rapidly gaining interest worldwide both in terms of research and industrial applications. The present work includes the characterization and modeling of jute- and coir-fiber-reinforced hybrid composite materials. The mechanical behavior of a two-panel plate and a sixpanel box structure is analyzed under various loading regimes by using the finite-element software ABAQUS®. Exhaustive parametric studies are also performed to obtain a clear insight into the relationships between various parameters and deflections of the panels and stress distributions in them. Deflections of both the structures are compared and found to be in good agreement with published results. To determine the mechanical behavior of natural-fiber-reinforced composite panels, a finite-element analysis is performed.

  15. Taxonomy of pasteurella anatipestifer. 1. DNA base composition and DNA-DNA hybridization analysis.

    Science.gov (United States)

    Bangun, A; Johnson, J L; Tripathy, D N

    1987-01-01

    DNA was isolated from 15 strains of Pasteurella anatipestifer and from one strain each of Moraxella nonliquefaciens, M. bovis, Pasteurella multocida, P. haemolytica, P. gallinarum, P. pneumotropica, and P. ureae. The guanine-plus-cytosine contents of P. anatipestifer ranged from 32 to 35 mole %, whereas those of Moraxella and Pasteurella spp. were much higher, ranging from 40 to 45 mole %. DNA-DNA hybridization analysis revealed that homology of nine P. anatipestifer strains to strains ATCC 11845 and PA 15 was 52 to 100%, whereas homology of Moraxella and Pasteurella strains to these strains was only 3 to 17%. Similarly, homology of P. anatipestifer strains, Moraxella, and Pasteurella species other than P. multocida to P. multocida reference strain P-2192 was low. These results strongly suggest that P. anatipestifer is genetically unrelated to either Pasteurella or Moraxella.

  16. An aggregation method of Markov graphs for the reliability analysis of hybrid systems

    Energy Technology Data Exchange (ETDEWEB)

    Schoenig, Raphael [Centre de Recherche en Automatique de Nancy (CRAN), 2, avenue de la Foret de Haye, 54516 Vandoeuvre-les-Nancy (France) and GFI Consulting, 12, rue Rouget de Lisle, 92442 Issy les Moulineaux (France)]. E-mail: raphael.schoenig@mpsa.com; Aubry, Jean-Francois [Centre de Recherche en Automatique de Nancy (CRAN), 2, avenue de la Foret de Haye, 54516 Vandoeuvre-les-Nancy (France)]. E-mail: jean-francois.aubry@isi.u-nancy.fr; Cambois, Thierry [PSA Peugeot Citroen, 18, rue des Fauvelles, 92256 La Garenne Colombes (France)]. E-mail: thierry.cambois@mpsa.com; Hutinet, Tony [GFI Consulting, 12, rue Rouget de Lisle, 92442 Issy les Moulineaux (France)]. E-mail: thutinet@gfi.fr

    2006-02-01

    To meet always increasing safety requirements in car industry, design and safety assessment methods are developed in order to fit the complexity of new embedded mecatronic systems. Hybrid (discrete/continuous) and dynamic features, specific to these systems, require choosing a suitable formalism. These features should also be considered in safety studies made all through the system design. The aim of this paper is to propose a quantitative analysis method based on the construction of an aggregated Markov graph, which allows a limitation of the combinatorial expansion. This graph is directly deducted from the Petri net modelling of the system. It is composed by a set of functional modes and a set of transitions to which statistical information regarding the system dynamics has been added.

  17. Diagnostic support for glaucoma using retinal images: a hybrid image analysis and data mining approach.

    Science.gov (United States)

    Yu, Jin; Abidi, Syed Sibte Raza; Artes, Paul; McIntyre, Andy; Heywood, Malcolm

    2005-01-01

    The availability of modern imaging techniques such as Confocal Scanning Laser Tomography (CSLT) for capturing high-quality optic nerve images offer the potential for developing automatic and objective methods for diagnosing glaucoma. We present a hybrid approach that features the analysis of CSLT images using moment methods to derive abstract image defining features. The features are then used to train classifers for automatically distinguishing CSLT images of normal and glaucoma patient. As a first, in this paper, we present investigations in feature subset selction methods for reducing the relatively large input space produced by the moment methods. We use neural networks and support vector machines to determine a sub-set of moments that offer high classification accuracy. We demonstratee the efficacy of our methods to discriminate between healthy and glaucomatous optic disks based on shape information automatically derived from optic disk topography and reflectance images.

  18. A study on flow distribution for integrated hybrid actuator by analysis of reed valve

    Energy Technology Data Exchange (ETDEWEB)

    Woo, Jang Mi; Kang, Seung Hwan; Ko, Han Seo [Sungkyunkwan University, Suwon (Korea, Republic of); Goo, Nam Seo; Li, Yong Zhe [Konkuk University, Seoul (Korea, Republic of)

    2016-05-15

    Many studies have been conducted recently on an integrated hybrid actuator due to the increasing need for unmanned aircraft and guided weapons. In this study, flow distribution was analyzed for a reed valve which was used for flow regulation to improve the performance of the actuator. By using a Fluid structural interaction (FSI) technique with Computational fluid dynamics (CFD) having a moving mesh, numerical analysis was performed according to the thickness, shape and driving frequency of the reed valve. From the calculated results, the maximum performance of the reed valve was found at the valve thickness of 0.15 mm and the driving frequency of 250 Hz for a no-load state. The optimum thickness and shape for the valve for each driving frequency were also realized.

  19. Analysis of a hybrid renewable energy system on the Mures valley using Homer

    Directory of Open Access Journals (Sweden)

    Dumitru Cristian Dragoş

    2011-12-01

    Full Text Available Renewable energy technologies offer the promise of clean, abundant energy gathered from self-renewing resources such as the sun, wind, earth, and plants. Virtually all regions of the world have renewable resources of one type or another. This paper deals with the modeling and analysis of a hybrid system based on renewable energy resources, located on the Mureş valley, using a dedicated software named HOMER. Different types and topologies of renewable resources for the energy supply are analyzed; a small consumer situated on the Mureş Valley is modeled based on a load curve. Finally, the energy flows between the renewable energy system and the local supplying network are analyzed.

  20. Highlighting hybridity: A critical discourse analysis of teacher talk in science classrooms

    Science.gov (United States)

    Hanrahan, Mary U.

    2006-01-01

    There is evidence that alienation from science is linked to the dominant discourse practices of science classrooms (cf. Lemke, J. L. (1990). Talking Science: Language, Learning, and Values. Norwood, NJ: Ablex). Yet, in secondary science education it is particularly hard to find evidence of curriculum reform that includes explicit changes in pedagogic discourses to accommodate the needs of students from a wide range of backgrounds. However, such evidence does exist and needs to be highlighted wherever it is found to help address social justice concerns in science education. In this article, I show how critical discourse analysis can be used to explore a way of challenging the dominant discourse in teacher - student interactions in science classrooms. My findings suggest a new way of moving toward more socially just science curricula in middle years and secondary classrooms by using hybrid discourses that can serve emancipatory purposes.

  1. A hybrid of bees algorithm and flux balance analysis (BAFBA) for the optimisation of microbial strains.

    Science.gov (United States)

    Choon, Yee Wen; Mohamad, Mohd Saberi; Deris, Safaai; Illias, Rosli Md

    2014-01-01

    The development of microbial production system has become popular in recent years as microbial hosts offer a number of unique advantages for both native and heterologous small-molecules. However, the main drawback is low yield or productivity of the desired products. Optimisation algorithms are implemented in previous works to identify the effects of gene knockout. Nevertheless, the previous works faced performance issue. Thus, a hybrid of Bees Algorithm and Flux Balance Analysis (BAFBA) is proposed in this paper to improve the performance in predicting optimal sets of gene deletion for maximising the growth rate and production yield of certain metabolite. This paper involves two datasets which are E. coli and S. cerevisiae. The list of knockout genes, growth rate and production yield after the deletion are the results from the experiments. BAFBA presents better results compared to the other methods and the identified list may be useful in solving genetic engineering problems.

  2. MorphologiCal and Cytogenetic Analysis on the Advanced Generations of Generic Hybrids between Brassica napus and Orychophragmus violaceu

    Institute of Scientific and Technical Information of China (English)

    Zhigang ZHAO; Dezhi DU; Zaiyun LI

    2012-01-01

    Objective This study aimed to reveal the genetic changes of advanced generation hybrids between Brassica napus and Orychophragmus violaceus. [Method] The morphological characteristics such as the plant shape, branching sites, leaf shape, leaf color, primary branches and secondary branches, as well as the cytolog- ical characteristics of the advanced generation hybrids (Fs-F10) between B. napus and O. violaceus were observed. [Result] The morphology analysis revealed that the hybrid progeny was more like B. rapa in leaf shape, leaf color, plant shape and ear- ly flowering phenotype, whereas more like B. napus in number of secondary branch- es, silique length and 1 000-seed weight. Analysis on the cytogenetics characteristics showed that these advanced inbred progenies were hypoploids with less than 38 chromosomes; moreover, all the chromosomes from O. violaceus had been lost. Chromosome pairings at meiotic diakinesis of hybrids between the advanced inbred progenies and B. rapa revealed that chromosomes lost in hypoploids possibly be- longed to the C genome of B. oleracea. With generations developing, chromosomes number of plants from two populations gradually increased and developed into the number of B. napus (2n=38). [Conclusion] This study will provide reference to reveal the source of chromosome lost in hypoploids and the morphological change of hybrids.

  3. HeteroGenius: A Framework for Hybrid Analysis of Heterogeneous Software Specifications

    Directory of Open Access Journals (Sweden)

    Manuel Giménez

    2014-01-01

    Full Text Available Nowadays, software artifacts are ubiquitous in our lives being an essential part of home appliances, cars, cell phones, and even in more critical activities like aeronautics and health sciences. In this context software failures may produce enormous losses, either economical or, in the worst case, in human lives. Software analysis is an area in software engineering concerned with the application of diverse techniques in order to prove the absence of errors in software pieces. In many cases different analysis techniques are applied by following specific methodological combinations that ensure better results. These interactions between tools are usually carried out at the user level and it is not supported by the tools. In this work we present HeteroGenius, a framework conceived to develop tools that allow users to perform hybrid analysis of heterogeneous software specifications. HeteroGenius was designed prioritising the possibility of adding new specification languages and analysis tools and enabling a synergic relation of the techniques under a graphical interface satisfying several well-known usability enhancement criteria. As a case-study we implemented the functionality of Dynamite on top of HeteroGenius.

  4. Uncertainty analysis and design optimization of hybrid rocket motor powered vehicle for suborbital flight

    Directory of Open Access Journals (Sweden)

    Zhu Hao

    2015-06-01

    Full Text Available In this paper, we propose an uncertainty analysis and design optimization method and its applications on a hybrid rocket motor (HRM powered vehicle. The multidisciplinary design model of the rocket system is established and the design uncertainties are quantified. The sensitivity analysis of the uncertainties shows that the uncertainty generated from the error of fuel regression rate model has the most significant effect on the system performances. Then the differences between deterministic design optimization (DDO and uncertainty-based design optimization (UDO are discussed. Two newly formed uncertainty analysis methods, including the Kriging-based Monte Carlo simulation (KMCS and Kriging-based Taylor series approximation (KTSA, are carried out using a global approximation Kriging modeling method. Based on the system design model and the results of design uncertainty analysis, the design optimization of an HRM powered vehicle for suborbital flight is implemented using three design optimization methods: DDO, KMCS and KTSA. The comparisons indicate that the two UDO methods can enhance the design reliability and robustness. The researches and methods proposed in this paper can provide a better way for the general design of HRM powered vehicles.

  5. Hybrid Evidence Theory-based Finite Element/Statistical Energy Analysis method for mid-frequency analysis of built-up systems with epistemic uncertainties

    Science.gov (United States)

    Yin, Shengwen; Yu, Dejie; Yin, Hui; Lü, Hui; Xia, Baizhan

    2017-09-01

    Considering the epistemic uncertainties within the hybrid Finite Element/Statistical Energy Analysis (FE/SEA) model when it is used for the response analysis of built-up systems in the mid-frequency range, the hybrid Evidence Theory-based Finite Element/Statistical Energy Analysis (ETFE/SEA) model is established by introducing the evidence theory. Based on the hybrid ETFE/SEA model and the sub-interval perturbation technique, the hybrid Sub-interval Perturbation and Evidence Theory-based Finite Element/Statistical Energy Analysis (SIP-ETFE/SEA) approach is proposed. In the hybrid ETFE/SEA model, the uncertainty in the SEA subsystem is modeled by a non-parametric ensemble, while the uncertainty in the FE subsystem is described by the focal element and basic probability assignment (BPA), and dealt with evidence theory. Within the hybrid SIP-ETFE/SEA approach, the mid-frequency response of interest, such as the ensemble average of the energy response and the cross-spectrum response, is calculated analytically by using the conventional hybrid FE/SEA method. Inspired by the probability theory, the intervals of the mean value, variance and cumulative distribution are used to describe the distribution characteristics of mid-frequency responses of built-up systems with epistemic uncertainties. In order to alleviate the computational burdens for the extreme value analysis, the sub-interval perturbation technique based on the first-order Taylor series expansion is used in ETFE/SEA model to acquire the lower and upper bounds of the mid-frequency responses over each focal element. Three numerical examples are given to illustrate the feasibility and effectiveness of the proposed method.

  6. Comparative Analysis of Torque and Acceleration of Pre- and Post-Transmission Parallel Hybrid Drivetrains

    Directory of Open Access Journals (Sweden)

    Zulkifli Saiful A.

    2016-01-01

    Full Text Available Parallel hybrid electric vehicles (HEV can be classified according to the location of the electric motor with respect to the transmission unit for the internal combustion engine (ICE: they can be pre-transmission or posttransmission parallel hybrid. A split-axle parallel HEV – in which the ICE and electric motor provide propulsion power to different axles – is a sub-type of the post-transmission hybrid, since addition of torque and power from the two power sources occurs after the vehicle’s transmission. The term ‘through-the-road’ (TTR hybrid is also used for the split-parallel HEV, since power coupling between the ICE and electric motor is not through some mechanical device but through the vehicle itself, its wheels and the road on which it moves. The present work presents torquespeed relationship of the split-parallel hybrid and analyses simulation results of torque profiles and acceleration performance of pre-transmission and post-transmission hybrid configurations, using three different sizes of electric motor. Different operating regions of the pre-trans and post-trans motors are observed, leading to different speed and torque profiles. Although ICE average efficiency in the post-trans hybrid is slightly lower than in the pre-trans hybrid, the post-trans hybrid vehicle has better fuel economy and acceleration performance than the pre-trans hybrid vehicle.

  7. Investigating Value Creation in a Community of Practice with Social Network Analysis in a Hybrid Online Graduate Education Program

    Science.gov (United States)

    Cowan, John E.; Menchaca, Michael P.

    2014-01-01

    This study reports an analysis of 10?years in the life of the Internet-based Master in Educational Technology program (iMET) at Sacramento State University. iMET is a hybrid educational technology master's program delivered 20% face to face and 80% online. The program has achieved a high degree of success, with a course completion rate of 93% and…

  8. The shallow water equations as a hybrid flow model for the numerical and experimental analysis of hydro power stations

    Energy Technology Data Exchange (ETDEWEB)

    Ostermann, Lars; Seidel, Christian [AG Regenerative Energien, Institut für Statik, TU Braunschweig, Beethovenstrasse 51, 38106 Braunschweig (Germany)

    2015-03-10

    The numerical analysis of hydro power stations is an important method of the hydraulic design and is used for the development and optimisation of hydro power stations in addition to the experiments with the physical submodel of a full model in the hydraulic laboratory. For the numerical analysis, 2D and 3D models are appropriate and commonly used.The 2D models refer mainly to the shallow water equations (SWE), since for this flow model a large experience on a wide field of applications for the flow analysis of numerous problems in hydraulic engineering already exists. Often, the flow model is verified by in situ measurements. In order to consider 3D flow phenomena close to singularities like weirs, hydro power stations etc. the development of a hybrid fluid model is advantageous to improve the quality and significance of the global model. Here, an extended hybrid flow model based on the principle of the SWE is presented. The hybrid flow model directly links the numerical model with the experimental data, which may originate from physical full models, physical submodels and in-situ measurements. Hence a wide field of application of the hybrid model emerges including the improvement of numerical models and the strong coupling of numerical and experimental analysis.

  9. Characterization of the complete mitochondrial genome of the hybrid Epinephelus moara♀ × Epinephelus lanceolatus♂, and phylogenetic analysis in subfamily epinephelinae

    Science.gov (United States)

    Gao, Fengtao; Wei, Min; Zhu, Ying; Guo, Hua; Chen, Songlin; Yang, Guanpin

    2017-06-01

    This study presents the complete mitochondrial genome of the hybrid Epinephelus moara♀× Epinephelus lanceolatus♂. The genome is 16886 bp in length, and contains 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, a light-strand replication origin and a control region. Additionally, phylogenetic analysis based on the nucleotide sequences of 13 conserved protein-coding genes using the maximum likelihood method indicated that the mitochondrial genome is maternally inherited. This study presents genomic data for studying phylogenetic relationships and breeding of hybrid Epinephelinae.

  10. Analysis of hybrid systems: An ounce of realism can save an infinity of states

    DEFF Research Database (Denmark)

    Fränzle, Martin

    1999-01-01

    no decision procedures due to inherent undecidability. Thus, unlike finite or timed automata, already linear hybrid automata are out-of-scope of fully automatic verification. In this article, we devise a new semi-decision method for safety of linear and polynomial hybrid systems which may only fail......Hybrid automata have been introduced in both control engineering and computer science as a formal model for the dynamics of hybrid discrete-continuous systems. In the case of so-called linear hybrid automata this formalization supports semi-decision procedures for state reachability, yet...... on pathological, practically uninteresting cases. These remaining cases are such that their safety depends on the complete absence of noise, a situation unlikely to occur in real hybrid systems. Furthermore, we show that if low probability effects of noise are ignored akin to the way they are suppressed...

  11. Experimental analysis of oligonucleotide microarray design criteria to detect deletions by comparative genomic hybridization

    Directory of Open Access Journals (Sweden)

    Moerman Donald G

    2008-10-01

    Full Text Available Abstract Background Microarray comparative genomic hybridization (CGH is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is widely used to assess copy number variants in healthy individuals and copy number aberrations associated with various diseases, syndromes and disease susceptibility. In model organisms such as Caenorhabditis elegans (C. elegans the technique has been applied to detect mutations, primarily deletions, in strains of interest. Although various constraints on oligonucleotide properties have been suggested to minimize non-specific hybridization and improve the data quality, there have been few experimental validations for CGH experiments. For genomic regions where strict design filters would limit the coverage it would also be useful to quantify the expected loss in data quality associated with relaxed design criteria. Results We have quantified the effects of filtering various oligonucleotide properties by measuring the resolving power for detecting deletions in the human and C. elegans genomes using NimbleGen microarrays. Approximately twice as many oligonucleotides are typically required to be affected by a deletion in human DNA samples in order to achieve the same statistical confidence as one would observe for a deletion in C. elegans. Surprisingly, the ability to detect deletions strongly depends on the oligonucleotide 15-mer count, which is defined as the sum of the genomic frequency of all the constituent 15-mers within the oligonucleotide. A similarity level above 80% to non-target sequences over the length of the probe produces significant cross-hybridization. We recommend the use of a fairly large melting temperature window of up to 10°C, the elimination of repeat sequences, the elimination of homopolymers longer than 5 nucleotides, and a threshold of -1 kcal/mol on the oligonucleotide self-folding energy. We observed very little difference in data

  12. Fluorescence in situ hybridization (FISH analysis of primary ocular adnexal MALT lymphoma

    Directory of Open Access Journals (Sweden)

    Harada Mine

    2006-10-01

    Full Text Available Abstract Background It remains unknown whether primary ocular adnexal extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma is a homogeneous entity, as there are few reports of the results of cytogenetic or molecular analyses of these tumors. Methods We performed interphase fluorescence in situ hybridization (FISH analysis to detect translocations and aneuploidy in 34 cases of primary ocular adnexal MALT lymphoma, and reviewed the histopathological findings. Correlations between the results of FISH analysis, the histopathological features and the clinical data were also analyzed. Results Among the 34 cases, FISH analysis revealed t(14;18(q32;q21 in one case, trisomy 3 in 21 cases (62%, and trisomy 18 in 16 cases (47%. The cases with trisomy 18 had significantly more prominent lymphoepithelial lesions (LELs and less nodularity in the tumors. In regard to the clinical correlations, tumors with trisomy 18 were observed predominantly in females and younger patients; also, in the majority of the cases, the tumor was of conjunctival origin. All the cases with recurrence showed trisomy 18 in the tumor. Conclusion Primary ocular adnexal MALT lymphoma is a significantly heterogeneous entity. Cases with trisomy 18 may have unique clinicopathological features.

  13. Hybrid-Wing-Body Vehicle Composite Fuselage Analysis and Case Study

    Science.gov (United States)

    Mukhopadhyay, Vivek

    2014-01-01

    Recent progress in the structural analysis of a Hybrid Wing-Body (HWB) fuselage concept is presented with the objective of structural weight reduction under a set of critical design loads. This pressurized efficient HWB fuselage design is presently being investigated by the NASA Environmentally Responsible Aviation (ERA) project in collaboration with the Boeing Company, Huntington Beach. The Pultruded Rod-Stiffened Efficient Unitized Structure (PRSEUS) composite concept, developed at the Boeing Company, is approximately modeled for an analytical study and finite element analysis. Stiffened plate linear theories are employed for a parametric case study. Maximum deflection and stress levels are obtained with appropriate assumptions for a set of feasible stiffened panel configurations. An analytical parametric case study is presented to examine the effects of discrete stiffener spacing and skin thickness on structural weight, deflection and stress. A finite-element model (FEM) of an integrated fuselage section with bulkhead is developed for an independent assessment. Stress analysis and scenario based case studies are conducted for design improvement. The FEM model specific weight of the improved fuselage concept is computed and compared to previous studies, in order to assess the relative weight/strength advantages of this advanced composite airframe technology

  14. Analysis Platform for Energy Efficiency Enhancement in Hybrid and Full Electric Vehicles

    Directory of Open Access Journals (Sweden)

    NICOLAICA, M.-O.

    2016-02-01

    Full Text Available The current paper presents a new virtual analysis method that is applied both on hybrid and electric vehicle architectures with the purpose of contributing to the improvement of energy efficiency. The study is based on Matlab modeling and simulation. A set of parameters are considered in order to assess the system performance. The benefit is given by the comparative overview obtained after the completed analysis. The effectiveness of the analysis method is confirmed by a sequence of simulation results combined in several case studies. The impulse of the research is given by the fact that the automotive market is focusing on wider simulation techniques and better control strategies that lead to more efficient vehicles. Applying the proposed method during design would improve the battery management and controls strategy. The advantage of this method is that the system behavior with regards to energy efficiency can be evaluated from an early concept phase. The results contribute to the actual necessity of driving more efficient and more environmental friendly vehicles.

  15. Analysis of a Substrate Integrated Waveguide Hybrid Ring (Rat-Race Coupler

    Directory of Open Access Journals (Sweden)

    Ramin Dehdasht-Heydari

    2014-01-01

    Full Text Available This paper presents an efficient analysis of a substrate integrated waveguide (SIW single-layer hybrid ring coupler (rat-race for millimeter-wave and microwave applications. The scattered field from each circular cylinder is expanded by cylindrical eigenfunctions with unknown coefficients that have been solved by electric and magnetic tangential boundary on each metallic via. The coupler S-matrix is calculated by using mode matching that uses the cylindrical vector expansion analysis to minimize the computational time and provides more physical insight. To achieve higher bandwidth, the radiuses of the coupler under analysis have been optimized in Matlab code by invasive weed optimization (IWO method, and the results have been verified by CST package. The return loss and the isolation are less than −15 dB, and −18 dB, respectively. The insertion loss is divided equally -3±0.2 dB, with 0±5 and 180±10 degrees in output ports over the operating frequency bandwidth and the agreement of phase differences in output ports has been examined objectively by feature selective validation (FSV technique.

  16. Measurement and analysis of self-noise in hybrid-driven underwater gliders

    Directory of Open Access Journals (Sweden)

    LIU Lu

    2017-08-01

    Full Text Available The Hybrid-driven Underwater Glider (HUG is a new type of submersible vehicle which combines the functions of traditional Autonomous Underwater Vehicles(AUVand Autonomous Underwater Gliders(AUG. In order to study its noise source distribution and basic self-noise characteristics, a self-noise acquisition system based on the HUG was designed and developed, and a noise analysis test carried out in a free-field pool. In August 2016, the sea trial of the Petrel II glider was conducted in the South China Sea, with observation data at a depth range of 1 000 m as the research object. The self-noise data of the glider platform under different working conditions was obtained through the step-by-step operation method. The experimental analysis and results show that the self-noise acquisition system is stable. The contribution of mechanical noise to self-noise is greatest when the glider works in the gliding mode, while the self-noise band above 500 Hz is closely related to the work of the buoyancy adjustment unit, and peaks at 1 kHz. According to the analysis of the basic characteristics of self-noise, this provides some guidance for the implementation of vibration and noise reduction.

  17. Laser speckle imaging of rat retinal blood flow with hybrid temporal and spatial analysis method

    Science.gov (United States)

    Cheng, Haiying; Yan, Yumei; Duong, Timothy Q.

    2009-02-01

    Noninvasive monitoring of blood flow in retinal circulation will reveal the progression and treatment of ocular disorders, such as diabetic retinopathy, age-related macular degeneration and glaucoma. A non-invasive and direct BF measurement technique with high spatial-temporal resolution is needed for retinal imaging. Laser speckle imaging (LSI) is such a method. Currently, there are two analysis methods for LSI: spatial statistics LSI (SS-LSI) and temporal statistical LSI (TS-LSI). Comparing these two analysis methods, SS-LSI has higher signal to noise ratio (SNR) and TSLSI is less susceptible to artifacts from stationary speckle. We proposed a hybrid temporal and spatial analysis method (HTS-LSI) to measure the retinal blood flow. Gas challenge experiment was performed and images were analyzed by HTS-LSI. Results showed that HTS-LSI can not only remove the stationary speckle but also increase the SNR. Under 100% O2, retinal BF decreased by 20-30%. This was consistent with the results observed with laser Doppler technique. As retinal blood flow is a critical physiological parameter and its perturbation has been implicated in the early stages of many retinal diseases, HTS-LSI will be an efficient method in early detection of retina diseases.

  18. Cost analysis of hybrid adaptive routing protocol for heterogeneous wireless sensor network

    Indian Academy of Sciences (India)

    NONITA SHARMA; AJAY K SHARMA

    2016-03-01

    This study aims to explore the impact of heterogeneity on a hybrid algorithm called Multi Adaptive Filter Algorithm by constructing series of experiments. Here, the simulations were made between ‘Total Energy Spent’ and ‘Number of Sources’ considering temporal correlation. The results were drawn from the trace information generated using ‘Monte Carlo’ simulation methods. After keen analysis, the results show that different levels of heterogeneity are best suited for correlated event detections. Moreover, based on the conclusions drawn,it can be safely inferred that n-level heterogeneity reduces the total energy spent close to 60%. Further, cost analysis recommends that adding progressive nodes preserves the cost factor in the bracket of 230–280$/Joule. Thenovel approach can immensely help the future solution providers to overcome the battery limitations of wireless sensor networks. This study provides insights into designing heterogeneous wireless sensor networks and aims atproviding the cost-benefit analysis that can be used in selecting the critical parameters of the network.

  19. Data Analysis for the NASA/Boeing Hybrid Laminar Flow Control Crossflow Experiment

    Science.gov (United States)

    Eppink, Jenna L.; Wlezien, Richard

    2011-01-01

    The Hybrid-Laminar Flow Control (HLFC) Crossflow Experiment, completed in 1995. generated a large database of boundary layer stability and transition data that was only partially analyzed before data analysis was abruptly ended in the late 1990's. Renewed interest in laminar flow technologies prompted additional data analysis, to integrate all data, including some post-test roughness and porosity measurements. The objective is to gain new insights into the effects of suction on boundary layer stability. A number of challenges were encountered during the data analysis, and their solutions are discussed in detail. They include the effect of the probe vibration, the effect of the time-varying surface temperature on traveling crossflow instabilities, and the effect of the stationary crossflow modes on the approximation of wall location. Despite the low turbulence intensity of the wind tunnel (0.01 to 0.02%), traveling crosflow disturbances were present in the data, in some cases at amplitudes up to 1% of the freestream velocity. However, the data suggests that transition was dominated by stationary crossflow. Traveling crossflow results and stationary data in the presence of suction are compared with linear parabolized stability equations results as a way of testing the quality of the results.

  20. Analysis on potential approaches to utilize genic male sterility in plant hybrid breeding

    Institute of Scientific and Technical Information of China (English)

    Li Xinqi; Yuan Longping; Xiao Jinhua; Xie fangming

    2005-01-01

    @@ The exploitation of plant heterosis is an effective approach to increasing the food production. The heterotic hybrid varieties in major crops such as rice,cotton, and wheat can show more than 20% yield advantage over best conventional ones under the same cultivation conditions. The difficulties in breeding elite male sterile lines and the inconveniences for commercial hybrid seed production are hampering the development of hybrid crops breeding.

  1. The incorrect usage of singular spectral analysis and discrete wavelet transform in hybrid models to predict hydrological time series

    Science.gov (United States)

    Du, Kongchang; Zhao, Ying; Lei, Jiaqiang

    2017-09-01

    In hydrological time series prediction, singular spectrum analysis (SSA) and discrete wavelet transform (DWT) are widely used as preprocessing techniques for artificial neural network (ANN) and support vector machine (SVM) predictors. These hybrid or ensemble models seem to largely reduce the prediction error. In current literature researchers apply these techniques to the whole observed time series and then obtain a set of reconstructed or decomposed time series as inputs to ANN or SVM. However, through two comparative experiments and mathematical deduction we found the usage of SSA and DWT in building hybrid models is incorrect. Since SSA and DWT adopt 'future' values to perform the calculation, the series generated by SSA reconstruction or DWT decomposition contain information of 'future' values. These hybrid models caused incorrect 'high' prediction performance and may cause large errors in practice.

  2. Comparative analysis of the mechanical and thermal properties of polyester hybrid composites reinforced by jute and glass fiber.

    Directory of Open Access Journals (Sweden)

    Braga, R. A

    2015-05-01

    Full Text Available This work describes the study to investigate and compare the mechanical and thermal properties of raw jute and glass fiber reinforced polyester hybrid composites. To improve the mechanical properties, jute fiber was hybridized with glass fiber. Polyester resin, jute and glass fibers were laminated in three weight ratios(77/23/0, 68/25/7 and 56/21/23 respectively to form composites. The tensile, flexural, impact, density, thermal and water absorption tests were carried out using hybrid composite samples. This study shows that the addition of jute fiber and glass fiber in polyester, increase the density, the impact energy, the tensile strength and the flexural strength, but decrease the loss mass in function of temperature and the water absorption. Morphological analysis was carried out to observe fracture behavior and fiber pull-out of the samples using scanning electron microscope.

  3. Analysis of the mechanical and thermal properties of jute and glass fiber as reinforcement epoxy hybrid composites.

    Science.gov (United States)

    Braga, R A; Magalhaes, P A A

    2015-11-01

    This work describes the study to investigate and compare the mechanical and thermal properties of raw jute and glass fiber reinforced epoxy hybrid composites. To improve the mechanical properties, jute fiber was hybridized with glass fiber. Epoxy resin, jute and glass fibers were laminated in three weight ratios (69/31/0, 68/25/7 and 64/18/19) respectively to form composites. The tensile, flexural, impact, density, thermal and water absorption tests were carried out using hybrid composite samples. This study shows that the addition of jute fiber and glass fiber in epoxy, increases the density, the impact energy, the tensile strength and the flexural strength, but decreases the loss mass in function of temperature and the water absorption. Morphological analysis was carried out to observe fracture behavior and fiber pull-out of the samples using scanning electron microscope. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Molecular analysis (RAPD-PCR) of inter-strain hybrids of the Paramecium aurelia species complex (Ciliophora, Protozoa).

    Science.gov (United States)

    Przyboś, Ewa; Prajer, Małgorzata; Greczek-Stachura, Magdalena

    2005-01-01

    RAPD-PCR analysis showed that species of the Paramecium aurelia complex possessed characteristic band patterns and that the majority were also polymorphic intra-specifically. A comparison of band patterns was performed for some inter-strain hybrids within P. primaurelia, P. tetraurelia, P. pentaurelia, P. septaurelia, P. octaurelia, P. decaurelia, P. dodecaurelia, P. tredecaurelia, and P. quadecaurelia to band patterns characteristic for the parental strains. The investigations, however, did not reveal a close correlation between the degree of inbreeding characteristic for the species and similarity of genotypes. A low similarity of hybrid and parental band patterns was observed in P. octaurelia, P. dodecaurelia, P. quadecaurelia and also P. primaurelia. A high similarity of band patterns of hybrid and parental strains was found in P. tetraurelia, P. septaurelia, P. decaurelia, and P. tredecaurelia.

  5. Comparative Analysis of the Endosperm Proteins Separated by 2-D Electrophoresis for Two Cultivars of Hybrid Rice (Oryza sativa L.)

    Institute of Scientific and Technical Information of China (English)

    Pingfang Yang; Shihua Shen; Tingyun Kuang

    2006-01-01

    Liangyoupeijiu is a two-parental-line, and Shanyou63 is a three-parental-line hybrid rice (Oryza sativa L.).Although both belong to the indica subspecies, they have obvious differences with respect to morphology,physiology and grain quality. Variations in endosperm protein compositions were studied by comparing the 2-D electrophoresis (2-DE) maps for these two cultivars of hybrid rice. After matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/MS) analysis, a 21-kDa precursor of 19-kDa globulin was identified as the major storage protein for both cultivars. Some isoforms of peroxiredoxin and seed maturation protein were found to only exist in Shanyou63, whereas aldose reductase and starch granule-bound starch synthase were only detected in Liangyoupeijiu. These data might provide a foundation for further comparative studies of these two cultivars of hybrid rice.

  6. An analysis platform for multiscale hydrogeologic modeling with emphasis on hybrid multiscale methods.

    Science.gov (United States)

    Scheibe, Timothy D; Murphy, Ellyn M; Chen, Xingyuan; Rice, Amy K; Carroll, Kenneth C; Palmer, Bruce J; Tartakovsky, Alexandre M; Battiato, Ilenia; Wood, Brian D

    2015-01-01

    One of the most significant challenges faced by hydrogeologic modelers is the disparity between the spatial and temporal scales at which fundamental flow, transport, and reaction processes can best be understood and quantified (e.g., microscopic to pore scales and seconds to days) and at which practical model predictions are needed (e.g., plume to aquifer scales and years to centuries). While the multiscale nature of hydrogeologic problems is widely recognized, technological limitations in computation and characterization restrict most practical modeling efforts to fairly coarse representations of heterogeneous properties and processes. For some modern problems, the necessary level of simplification is such that model parameters may lose physical meaning and model predictive ability is questionable for any conditions other than those to which the model was calibrated. Recently, there has been broad interest across a wide range of scientific and engineering disciplines in simulation approaches that more rigorously account for the multiscale nature of systems of interest. In this article, we review a number of such approaches and propose a classification scheme for defining different types of multiscale simulation methods and those classes of problems to which they are most applicable. Our classification scheme is presented in terms of a flowchart (Multiscale Analysis Platform), and defines several different motifs of multiscale simulation. Within each motif, the member methods are reviewed and example applications are discussed. We focus attention on hybrid multiscale methods, in which two or more models with different physics described at fundamentally different scales are directly coupled within a single simulation. Very recently these methods have begun to be applied to groundwater flow and transport simulations, and we discuss these applications in the context of our classification scheme. As computational and characterization capabilities continue to improve

  7. Hybrid Microfluidic Platform for Multifactorial Analysis Based on Electrical Impedance, Refractometry, Optical Absorption and Fluorescence

    National Research Council Canada - National Science Library

    Pereira, Fábio; Bernacka-Wojcik, Iwona; Ribeiro, Rita; Lobato, Maria; Fortunato, Elvira; Martins, Rodrigo; Igreja, Rui; Jorge, Pedro; Águas, Hugo; Oliva, Abel

    2016-01-01

    ...: electrical impedance, refractometry, optical absorption and fluorescence. We present the rationale for the design and the details of the microfabrication of this multifactorial hybrid microfluidic chip...

  8. A novel simplified model for torsional vibration analysis of a series-parallel hybrid electric vehicle

    Science.gov (United States)

    Tang, Xiaolin; Yang, Wei; Hu, Xiaosong; Zhang, Dejiu

    2017-02-01

    In this study, based on our previous work, a novel simplified torsional vibration dynamic model is established to study the torsional vibration characteristics of a compound planetary hybrid propulsion system. The main frequencies of the hybrid driveline are determined. In contrast to vibration characteristics of the previous 16-degree of freedom model, the simplified model can be used to accurately describe the low-frequency vibration property of this hybrid powertrain. This study provides a basis for further vibration control of the hybrid powertrain during the process of engine start/stop.

  9. Organization and variation analysis of 5S rDNA in different ploidy-level hybrids of red crucian carp × topmouth culter.

    Science.gov (United States)

    He, Weiguo; Qin, Qinbo; Liu, Shaojun; Li, Tangluo; Wang, Jing; Xiao, Jun; Xie, Lihua; Zhang, Chun; Liu, Yun

    2012-01-01

    Through distant crossing, diploid, triploid and tetraploid hybrids of red crucian carp (Carassius auratus red var., RCC♀, Cyprininae, 2n = 100) × topmouth culter (Erythroculter ilishaeformis Bleeker, TC♂, Cultrinae, 2n = 48) were successfully produced. Diploid hybrids possessed 74 chromosomes with one set from RCC and one set from TC; triploid hybrids harbored 124 chromosomes with two sets from RCC and one set from TC; tetraploid hybrids had 148 chromosomes with two sets from RCC and two sets from TC. The 5S rDNA of the three different ploidy-level hybrids and their parents were sequenced and analyzed. There were three monomeric 5S rDNA classes (designated class I: 203 bp; class II: 340 bp; and class III: 477 bp) in RCC and two monomeric 5S rDNA classes (designated class IV: 188 bp, and class V: 286 bp) in TC. In the hybrid offspring, diploid hybrids inherited three 5S rDNA classes from their female parent (RCC) and only class IV from their male parent (TC). Triploid hybrids inherited class II and class III from their female parent (RCC) and class IV from their male parent (TC). Tetraploid hybrids gained class II and class III from their female parent (RCC), and generated a new 5S rDNA sequence (designated class I-N). The specific paternal 5S rDNA sequence of class V was not found in the hybrid offspring. Sequence analysis of 5S rDNA revealed the influence of hybridization and polyploidization on the organization and variation of 5S rDNA in fish. This is the first report on the coexistence in vertebrates of viable diploid, triploid and tetraploid hybrids produced by crossing parents with different chromosome numbers, and these new hybrids are novel specimens for studying the genomic variation in the first generation of interspecific hybrids, which has significance for evolution and fish genetics.

  10. Organization and variation analysis of 5S rDNA in different ploidy-level hybrids of red crucian carp × topmouth culter.

    Directory of Open Access Journals (Sweden)

    Weiguo He

    Full Text Available Through distant crossing, diploid, triploid and tetraploid hybrids of red crucian carp (Carassius auratus red var., RCC♀, Cyprininae, 2n = 100 × topmouth culter (Erythroculter ilishaeformis Bleeker, TC♂, Cultrinae, 2n = 48 were successfully produced. Diploid hybrids possessed 74 chromosomes with one set from RCC and one set from TC; triploid hybrids harbored 124 chromosomes with two sets from RCC and one set from TC; tetraploid hybrids had 148 chromosomes with two sets from RCC and two sets from TC. The 5S rDNA of the three different ploidy-level hybrids and their parents were sequenced and analyzed. There were three monomeric 5S rDNA classes (designated class I: 203 bp; class II: 340 bp; and class III: 477 bp in RCC and two monomeric 5S rDNA classes (designated class IV: 188 bp, and class V: 286 bp in TC. In the hybrid offspring, diploid hybrids inherited three 5S rDNA classes from their female parent (RCC and only class IV from their male parent (TC. Triploid hybrids inherited class II and class III from their female parent (RCC and class IV from their male parent (TC. Tetraploid hybrids gained class II and class III from their female parent (RCC, and generated a new 5S rDNA sequence (designated class I-N. The specific paternal 5S rDNA sequence of class V was not found in the hybrid offspring. Sequence analysis of 5S rDNA revealed the influence of hybridization and polyploidization on the organization and variation of 5S rDNA in fish. This is the first report on the coexistence in vertebrates of viable diploid, triploid and tetraploid hybrids produced by crossing parents with different chromosome numbers, and these new hybrids are novel specimens for studying the genomic variation in the first generation of interspecific hybrids, which has significance for evolution and fish genetics.

  11. Design and Analysis of Electro-mechanical Hybrid Anti-lock Braking System for Hybrid Electric Vehicle Utilizing Motor Regenerative Braking

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jianlong; YIN Chengliang; ZHANG Jianwu

    2009-01-01

    Braking on low adhesion-coefficient roads, hybrid electric vehicle's motor regenerative torque is switched off to safeguard the normal anti-lock braking system (ABS) function. When the ABS control is terminated, the motor regenerative braking is readmitted.Aiming at avoiding permanent cycles from hydraulic anti-lock braking to motor regenerative braking, a novel electro-mechanical hybrid anti-lock braking system using fuzzy logic is designed. Different from the traditional single control structure, this system has a two-layered hierarchical structure. The first layer is responsible for harmonious adjustment or interaction between regenerative system and anti-lock braking system. The second layer is responsible for braking torque distribution and adjustment. The closed-loop simulation model is built. Control strategy and method for coordination between regenerative and anti-lock braking are developed. Simulation braking on low adhesion-coefficient roads with fuzzy logic control and real vehicle braking field test are presented. The results from simulating analysis and experiment show braking performance of the vehicle is perfect, harmonious coordination between regenerative and anti-lock braking function, significant amount of braking energy can be recovered and the proposed control strategy and method are effective.

  12. Genetic analysis of hybrid seed formation ability of Brassica rapa in intergeneric crossings with Raphanus sativus.

    Science.gov (United States)

    Tonosaki, K; Michiba, K; Bang, S W; Kitashiba, H; Kaneko, Y; Nishio, T

    2013-03-01

    A hybridization barrier leads to the inability of seed formation after intergeneric crossings between Brassica rapa and Raphanus sativus. Most B. rapa lines cannot set intergeneric hybrid seeds because of embryo breakdown, but a B. rapa line obtained from turnip cultivar 'Shogoin-kabu' is able to produce a large number of hybrid seeds as a maternal parent by crossings with R. sativus. In 'Shogoin-kabu' crossed with R. sativus, developments of embryos and endosperms were slower than those in intraspecific crossings, but some of them grew to mature seeds without embryo breakdown. Intergeneric hybrid seeds were obtained in a 'Shogoin-kabu' line at a rate of 0.13 per pollinated flower, while no hybrid seeds were obtained in a line developed from Chinese cabbage cultivar 'Chiifu'. F(1) hybrid plants between the lines of 'Shogoin-kabu' and 'Chiifu' set a larger number of hybrid seeds per flower, 0.68, than both the parental lines. Quantitative trait loci (QTLs) for hybrid seed formation were analyzed after intergeneric crossings using two different F(2) populations derived from the F(1) hybrids, and three QTLs with significant logarithm of odds scores were detected. Among them, two QTLs, i.e., one in linkage group A10 and the other in linkage group A01, were detected in both the F(2) populations. These two QTLs had contrary effects on the number of hybrid seeds. Epistatic interaction between these two QTLs was revealed. Possible candidate genes controlling hybrid seed formation ability in QTL regions were inferred using the published B. rapa genome sequences.

  13. The Two Faces of Security in Hybrid Political Orders: A Framework for Analysis and Research

    Directory of Open Access Journals (Sweden)

    Robin Luckham

    2013-09-01

    authority and capacity to deliver security are weak, disputed or compromised by special interests; and (iii “securitised policy spaces” in which international actors collaborate to ensure peace and fulfil their responsibility to protect vulnerable end-users in unsecured regions. In making these distinctions we argue that similar analytical lenses can be turned upon international actors in securitised policy spaces as well as upon state and non-state security actors. The concluding section argues that such a reframing of the security and development debate demands not just new modes of analysis but also fresh approaches to research designed both to provide insights into the vernacular understandings, coping strategies and potential agency of end-users and to uncover the informal networks, alliances and covert strategies of the multiple actors determining their security in hybrid political orders. This paper builds upon a systematic literature search undertaken by the Justice and Security Research Programme (JSRP at the London School of Economics (LSE funded by the UK’s Department for International Development (DFID. The search itself and its main findings are discussed in Luckham and Kirk (2012 and Luckham and Kirk (2013.

  14. Analysis tools for simulation of hybrid systems; Herramientas de analisis para simulacion de sistemas hibridos

    Energy Technology Data Exchange (ETDEWEB)

    Guillen S, Omar; Mejia N, Fortino [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2005-07-01

    In order to facilitate and to simplify the development and analysis of a Hybrid System in reference to its design, construction, operation and maintenance, it turns out optimal to carry out the simulation of this one by means of software, with which a significant reduction in the investment costs is obtained. Given the mix of technology of electrical generation which is involved in a hybrid system, it is very important to have a tool integrated with specialized packages of calculation (software), that allow to carry out the simulation tasks of the operational functioning of these systems. Combined with the former, one must not fail to consider the operation characteristics, the facilities of the user, the clarity in the obtained results and the possibility of its validation with respect to prototypes orchestrated in field. Equally, it is necessary to consider the identification of tasks involved in relation to the place of installation of this electrification technology. At the moment, the hybrid systems technology still is in a stage of development in the international level, and exist important limitations as far as the methodology availability and engineering tools for the optimum design of these systems. With the development of this paper, it is intended to contribute to the advance of the technology and to count on own tools to solve the described series of problems. In this article are described the activities that more impact have in the design and development of hybrid systems, as well as the identification of variables, basic characteristics and form of validation of tools in the integration of a methodology for the simulation of these systems, facilitating their design and development. [Spanish] Para facilitar y simplificar el desarrollo y analisis de un Sistema Hibrido en lo que refiere a su diseno, construccion, operacion y mantenimiento, resulta optimo efectuar la simulacion de este por medio de un software, con lo que se obtiene una reduccien

  15. Hybrid model of arm for analysis of regional blood oxygenation in non-invasive optical diagnostics

    Science.gov (United States)

    Nowocień, Sylwester; Mroczka, Janusz

    2017-06-01

    The paper presents a new comprehensive approach to modeling and analysis of processes occurring during the blood flow in the arm's small vessels as well as non-invasive measurement method of mixed venous oxygen saturation. During the work, a meta-analysis of available physiological data was performed and based on its result a hybrid model of forearm vascular tree was proposed. The model, in its structure, takes into account a classical nonlinear hydro-electric analogy in conjunction with light-tissue interaction. Several geometries of arm vascular tree obtained from magnetic resonance angiography (MRA) image were analyzed which allowed to proposed the structure of electrical analog network. Proposed model allows to simulate the behavior of forearm blood flow from the vascular tree mechanics point of view, as well as effects of the impact of cuff and vessel wall mechanics on the recorded photoplethysmographic signals. In particular, it allows to analyze the reaction and anatomical effects in small vessels and microcirculation caused by occlusive maneuver in selected techniques, what was of particular interest to authors and motivation to undertake research in this area. Preliminary studies using proposed model showed that inappropriate selection of occlusion maneuver parameters (e.g. occlusion time, cuff pressure etc.), cause dangerous turbulence of blood flow in the venous section of the vascular tree.

  16. Design analysis and performance assessment of hybrid magnetic bearings for a rotary centrifugal blood pump.

    Science.gov (United States)

    Ren, Zhaohui; Jahanmir, Said; Heshmat, Hooshang; Hunsberger, Andrew Z; Walton, James F

    2009-01-01

    A hybrid magnetic bearing system was designed for a rotary centrifugal blood pump being developed to provide long-term circulatory support for heart failure patients. This design consists of two compact bearings to suspend the rotor in five degrees-of-freedom with single axis active control. Permanent magnets are used to provide passive radial support and electromagnets to maintain axial stability of the rotor. Characteristics of the passive radial and active thrust magnetic bearing system were evaluated by the electromagnetic finite element analysis. A proportional-integral-derivative controller with force balance algorithm was implemented for closed loop control of the magnetic thrust bearing. The control position is continuously adjusted based on the electrical energy in the bearing coils, and thus passive magnetic forces carry static thrust loads to minimize the bearing current. Performance of the magnetic bearing system with associated control algorithm was evaluated at different operating conditions. The bearing current was significantly reduced with the force balance control method and the power consumption was below 0.5 W under various thrust loads. The bearing parameters predicted by the analysis were validated by the experimental data.

  17. Stress analysis and damage evaluation of flawed composite laminates by hybrid-numerical methods

    Science.gov (United States)

    Yang, Yii-Ching

    1992-01-01

    Structural components in flight vehicles is often inherited flaws, such as microcracks, voids, holes, and delamination. These defects will degrade structures the same as that due to damages in service, such as impact, corrosion, and erosion. It is very important to know how a structural component can be useful and survive after these flaws and damages. To understand the behavior and limitation of these structural components researchers usually do experimental tests or theoretical analyses on structures with simulated flaws. However, neither approach has been completely successful. As Durelli states that 'Seldom does one method give a complete solution, with the most efficiency'. Examples of this principle is seen in photomechanics which additional strain-gage testing can only average stresses at locations of high concentration. On the other hand, theoretical analyses including numerical analyses are implemented with simplified assumptions which may not reflect actual boundary conditions. Hybrid-Numerical methods which combine photomechanics and numerical analysis have been used to correct this inefficiency since 1950's. But its application is limited until 1970's when modern computer codes became available. In recent years, researchers have enhanced the data obtained from photoelasticity, laser speckle, holography and moire' interferometry for input of finite element analysis on metals. Nevertheless, there is only few of literature being done on composite laminates. Therefore, this research is dedicated to this highly anisotropic material.

  18. Stochastic segmentation models for array-based comparative genomic hybridization data analysis.

    Science.gov (United States)

    Lai, Tze Leung; Xing, Haipeng; Zhang, Nancy

    2008-04-01

    Array-based comparative genomic hybridization (array-CGH) is a high throughput, high resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically involves estimation of the underlying chromosome copy numbers from the log fluorescence ratios and segmenting the chromosome into regions with the same copy number at each location. We propose for the analysis of array-CGH data, a new stochastic segmentation model and an associated estimation procedure that has attractive statistical and computational properties. An important benefit of this Bayesian segmentation model is that it yields explicit formulas for posterior means, which can be used to estimate the signal directly without performing segmentation. Other quantities relating to the posterior distribution that are useful for providing confidence assessments of any given segmentation can also be estimated by using our method. We propose an approximation method whose computation time is linear in sequence length which makes our method practically applicable to the new higher density arrays. Simulation studies and applications to real array-CGH data illustrate the advantages of the proposed approach.

  19. Optimization of CNC End Milling using Hybrid Taguchi Method using Principal Components Analysis and Utility Theory

    Directory of Open Access Journals (Sweden)

    Anish Nair

    2013-08-01

    Full Text Available In order to improve the quality and productivity the present study highlights the optimization of CNC end milling process parameters to provide a good surface finish. Surface finish has been identified as one of the main quality attributes and is directly related to the productivity of a machine. In this paper an attempt has been made to optimize the process such that the best surface roughness value can be obtained in a process. Hence a multi objective optimization problem has been obtained which can be solved by the hybrid Taguchi method comprising of principal components analysis as well as by utility theory. In this work, Individual response correlation has been eliminated first by mean of Principal Component Analysis (PCA to meet the basic assumption of Taguchi method. Correlated responses have been transformed into uncorrelated quality indices called as principal components. Quality loss estimates have been calculated from the principal components and the utility values are found out for the same. Then the overall utility index has been calculated. Finally, Taguchi method has been used to solve the optimization problem.

  20. Experimental and theoretical analysis of a hybrid solar thermoelectric generator with forced convection cooling

    Science.gov (United States)

    Sundarraj, Pradeepkumar; Taylor, Robert A.; Banerjee, Debosmita; Maity, Dipak; Sinha Roy, Susanta

    2017-01-01

    Hybrid solar thermoelectric generators (HSTEGs) have garnered significant research attention recently due to their potential ability to cogenerate heat and electricity. In this paper, theoretical and experimental investigations of the electrical and thermal performance of a HSTEG system are reported. In order to validate the theoretical model, a laboratory scale HSTEG system (based on forced convection cooling) is developed. The HSTEG consists of six thermoelectric generator modules, an electrical heater, and a stainless steel cooling block. Our experimental analysis shows that the HSTEG is capable of producing a maximum electrical power output of 4.7 W, an electrical efficiency of 1.2% and thermal efficiency of 61% for an average temperature difference of 92 °C across the TEG modules with a heater power input of 382 W. These experimental results of the HSTEG system are found to be in good agreement with the theoretical prediction. This experimental/theoretical analysis can also serve as a guide for evaluating the performance of the HSTEG system with forced convection cooling.

  1. Analysis of SMA Hybrid Composite Structures in MSC.Nastran and ABAQUS

    Science.gov (United States)

    Turner, Travis L.; Patel, Hemant D.

    2005-01-01

    A thermoelastic constitutive model for shape memory alloy (SMA) actuators and SMA hybrid composite (SMAHC) structures was recently implemented in the commercial finite element codes MSC.Nastran and ABAQUS. The model may be easily implemented in any code that has the capability for analysis of laminated composite structures with temperature dependent material properties. The model is also relatively easy to use and requires input of only fundamental engineering properties. A brief description of the model is presented, followed by discussion of implementation and usage in the commercial codes. Results are presented from static and dynamic analysis of SMAHC beams of two types; a beam clamped at each end and a cantilever beam. Nonlinear static (post-buckling) and random response analyses are demonstrated for the first specimen. Static deflection (shape) control is demonstrated for the cantilever beam. Approaches for modeling SMAHC material systems with embedded SMA in ribbon and small round wire product forms are demonstrated and compared. The results from the commercial codes are compared to those from a research code as validation of the commercial implementations; excellent correlation is achieved in all cases.

  2. 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis.

    Science.gov (United States)

    Takeda, Maiko; Kasai, Takahiko; Enomoto, Yasunori; Takano, Masato; Morita, Kouhei; Kadota, Eiji; Nonomura, Akitaka

    2010-05-01

    Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs). Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens. Although the diagnostic utility of 9p21 homozygous deletion by fluorescence in situ hybridization (FISH) analysis has been reported only recently, it has not been well demonstrated. The purpose of this study is to evaluate the diagnostic utility of 9p21 homozygous deletion assessed by FISH in mesothelial neoplasm and hyperplasia of Japanese patients using paraffin-embedded tissue. Simultaneously, p16 protein immunoexpression was explored as a potential diagnostic aid. FISH analysis demonstrated 9p21 deletion in 35 of 40 cases with MM (88%) (P multicystic tumor, reactive mesothelial hyperplasia or pleuritis showed 9p21 deletion (P < 0.005). 9p21 homozygous deletion correlated well with p16 protein expression in the tumor cells. Our study suggests that 9p21 homozygous deletion assessed by FISH on paraffin-embedded tissue may be very useful for differentiating MM from reactive mesothelial proliferation.

  3. Dynamical Behavior and Stability Analysis in a Hybrid Epidemiological-Economic Model with Incubation

    Directory of Open Access Journals (Sweden)

    Chao Liu

    2014-01-01

    Full Text Available A hybrid SIR vector disease model with incubation is established, where susceptible host population satisfies the logistic equation and the recovered host individuals are commercially harvested. It is utilized to discuss the transmission mechanism of infectious disease and dynamical effect of commercial harvest on population dynamics. Positivity and permanence of solutions are analytically investigated. By choosing economic interest of commercial harvesting as a parameter, dynamical behavior and local stability of model system without time delay are studied. It reveals that there is a phenomenon of singularity induced bifurcation as well as local stability switch around interior equilibrium when economic interest increases through zero. State feedback controllers are designed to stabilize model system around the desired interior equilibria in the case of zero economic interest and positive economic interest, respectively. By analyzing corresponding characteristic equation of model system with time delay, local stability analysis around interior equilibrium is discussed due to variation of time delay. Hopf bifurcation occurs at the critical value of time delay and corresponding limit cycle is also observed. Furthermore, directions of Hopf bifurcation and stability of the bifurcating periodic solutions are studied. Numerical simulations are carried out to show consistency with theoretical analysis.

  4. Back Analysis of Geomechanical Parameters Using Hybrid Algorithm Based on Difference Evolution and Extreme Learning Machine

    Directory of Open Access Journals (Sweden)

    Zhan-ping Song

    2015-01-01

    Full Text Available Since the geological bodies where tunnels are located have uncertain and complex characteristics, the inverse problem plays an important role in geotechnical engineering. In order to improve the accuracy and speed of surrounding rock identification, the back analysis objective function with usage of the displacement and stress monitoring data has been constructed, with a hybrid algorithm proposed. An extreme learning machine (ELM is employed with optimal architecture trained by the difference evolution (DE arithmetic. First, the three-dimensional numerical simulation is used in the creation of training and testing samples for ELM model construction. Second, the nonlinear relationship between rock parameters and displacement is constructed by numerical simulation. Finally, the geophysics parameters are obtained by DE optimization arithmetic taking into consideration the monitoring data including both displacement and pressure. This method had been applied in the Fusong highway tunnel in Fusong City of China’s Jilin Province, with a good effect obtained. It takes full advantage of DE and ELM and has both calculation speed and precision in the back analysis.

  5. Failure mode and effects analysis using intuitionistic fuzzy hybrid weighted Euclidean distance operator

    Science.gov (United States)

    Liu, Hu-Chen; Liu, Long; Li, Ping

    2014-10-01

    Failure mode and effects analysis (FMEA) has shown its effectiveness in examining potential failures in products, process, designs or services and has been extensively used for safety and reliability analysis in a wide range of industries. However, its approach to prioritise failure modes through a crisp risk priority number (RPN) has been criticised as having several shortcomings. The aim of this paper is to develop an efficient and comprehensive risk assessment methodology using intuitionistic fuzzy hybrid weighted Euclidean distance (IFHWED) operator to overcome the limitations and improve the effectiveness of the traditional FMEA. The diversified and uncertain assessments given by FMEA team members are treated as linguistic terms expressed in intuitionistic fuzzy numbers (IFNs). Intuitionistic fuzzy weighted averaging (IFWA) operator is used to aggregate the FMEA team members' individual assessments into a group assessment. IFHWED operator is applied thereafter to the prioritisation and selection of failure modes. Particularly, both subjective and objective weights of risk factors are considered during the risk evaluation process. A numerical example for risk assessment is given to illustrate the proposed method finally.

  6. Sentiment Analysis of Movie Reviews using Hybrid Method of Naive Bayes and Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    M.Govindarajan

    2013-12-01

    Full Text Available The area of sentiment mining (also called sentiment extraction, opinion mining, opinion extraction, sentiment analysis, etc. has seen a large increase in academic interest in the last few years. Researchers in the areas of natural language processing, data mining, machine learning, and others have tested a variety of methods of automating the sentiment analysis process. In this research work, new hybrid classification method is proposed based on coupling classification methods using arcing classifier and their performances are analyzed in terms of accuracy. A Classifier ensemble was designed using Naive Bayes (NB, Genetic Algorithm (GA. In the proposed work, a comparative study of the effectiveness of ensemble technique is made for sentiment classification. The ensemble framework is applied to sentiment classification tasks, with the aim of efficiently integrating different feature sets and classification algorithms to synthesize a more accurate classification procedure. The feasibility and the benefits of the proposed approaches are demonstrated by means of movie review that is widely used in the field of sentiment classification. A wide range of comparative experiments are conducted and finally, some in-depth discussion is presented and conclusions are drawn about the effectiveness of ensemble technique for sentiment classification.

  7. Unit Sizing and Cost Analysis of Renewable Energy based Hybrid Power Generation System - A Case Study

    Directory of Open Access Journals (Sweden)

    Nitin AGARWAL

    2014-01-01

    Full Text Available A simulation model is developed for optimal sizing and analysis of a PV-diesel-battery based hybrid power generation system with the objectives to minimize life cycle cost and CO2 emission, while maintaining the desired system autonomy. A case study of a boy’s hostel in Moradabad district is taken for analysis purposes. It has 91 rooms with a capacity of 3 boys in each room. The decision variables included in the optimization methodology are total PV area, number of PV modules of 600 Wp, diesel generator power, fuel consumption per year and number of 24 V and 150 Ah batteries. The simulation result shows that the PV percentage of 86 % and diesel penetration of 14 % gives the most optimized solution with minimum LCC of $110,547 and average CO2 emission of 28 kg/day. The developed model has been validated by comparing its results with earlier research work.doi:10.14456/WJST.2014.24

  8. Functionalization of hybrid monolithic columns via thiol-ene click reaction for proteomics analysis.

    Science.gov (United States)

    Liu, Zhongshan; Liu, Jing; Liu, Zheyi; Wang, Hongwei; Ou, Junjie; Ye, Mingliang; Zou, Hanfa

    2017-05-19

    The vinyl-functionalized hybrid monolithic columns (75 and 150μm i.d.) were prepared via sol-gel chemistry of tetramethoxysilane (TMOS) and vinyltrimethoxysilane (VTMS). The content of accessible vinyl groups was further improved after the monolithic column was post-treated with vinyldimethylethoxysilane (VDMES). The surface properties of monolithic columns were tailored via thiol-ene click reaction by using 1-octadecanethiol, sodium 3-mercapto-1-propanesulfonate and 2,2'-(ethylenedioxy)diethanethiol/vinylphosphonic acid, respectively. The preparing octadecyl-functionalized monolithic columns were adopted for proteomics analysis in cLC-MS/MS. A 37-cm-long×75-μm-i.d. monolithic column could identify 3918 unique peptides and 1067 unique proteins in the tryptic digest of proteins from HeLa cells. When a 90-cm-long×75-μm-i.d. monolithic column was used, the numbers of unique peptides and proteins were increased by 82% and 32%, respectively. Furthermore, strong cation exchange (SCX) monolithic columns (4cm in length×150μm i.d.) were also prepared and coupled with the 37-cm-long×75-μm-i.d. octadecyl-functionalized monolithic column for two-dimensional SCX-RPLC-MS/MS analysis, which could identify 17114 unique peptides and 3211 unique proteins. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. [Analysis of chromosome composition in interspecific embryonic stem hybrid cells of mice].

    Science.gov (United States)

    Pristiazhniuk, I E; Matveeva, N M; Grafodatskiĭ, A S; Serdiukova, N A; Serov, O L

    2010-01-01

    Chromosome complements of twenty hybrid clones obtained by fusion of Mus musculus embryonic stem cells (ESC) and M. caroli splenocytes were studied. Using of double-color in situ hybridization with chromosome- and species-specific probes we were able to detect the parental origin for each chromosome in hybrid cells. Based on parental chromosome ratio, all 20 hybrid clones were separated in some different groups: from the group containing practically tetraploid M. musculus genome with single M. caroli chromosomes to hybrids with dominance of M. caroli chromosome homologues. In 8 hybrid cells clones we observed prevalence of chromosomes originated from ESC in ratio from 5:1 to 3:1. Another hybrid cells clones have either equal (1:1, 1:2) ratio of M. musculus to M. caroli chromosomes or with the prevalence of ESC- (2:1) or splenocyte- (1:2) originated parental chromosome homologues. In 3 hybrid cells clones, we observed preferable segregation of ESC-originated pluripotent chromosomes. This phenomenon was found for the first time and it possibly indicates compensation of the epigenetic differences between parental chromosomes of ESC- and splenocyte-origination.

  10. Blind Evaluation of Hybrid Protein Structure Analysis Methods based on Cross-Linking.

    Science.gov (United States)

    Belsom, Adam; Schneider, Michael; Brock, Oliver; Rappsilber, Juri

    2016-07-01

    Hybrid methods combine experimental data and computational modeling to analyze protein structures that are elusive to structure determination. To spur the development of hybrid methods, we propose to test them in the context of the CASP experiment and would like to invite experimental groups to participate in this initiative.

  11. Character Association And Path Analysis in Inter-Racial Hybrids in Rice (Oryza Sativa L.

    Directory of Open Access Journals (Sweden)

    M. Gunasekaran*, N. Nadarajan and S.V.S.R.K. Netaji

    2010-07-01

    Full Text Available The studies on the correlation of the traits and their relative direct and indirect effects on yield are important, as they arehelpful to adopt suitable selection procedure for yield improvement in inter-racial breeding programmes. In the present study,15 wide compatible genotypes (11 tropical japonicas and four indicas were crossed with six non-wide compatible genotypes(three each of indicas and japonicas and 90 hybrids were obtained. With an emphasis on inter sub-specific hybrids, the 90hybrids obtained as above were classified into four types viz., i tropical japonica (11 x indica (3 type hybrids (33, iitropical japonica (11 x japonica (3 type hybrids (33, iii indica (4 x indica (3 type hybrids (12 and iv indica (4 xjaponica (3 type hybrids (12. All the four types of hybrids were evaluated separately in Randomized Complete Block Designwith two replications. The findings, in general for all the four types of cross combinations, suggested that productive tillersfollowed by filled grains per panicle and 100 grain weight are the important characters to bring about the improvement inyield potential of rice. The productive tillers attains importance as it is easier to record and simultaneously will increase filledgrains thereby the grain yield.

  12. Analysis of genetic and environmental effects on hybrid poplar rooting in Central and Northern Minnesota, USA

    Science.gov (United States)

    Ronald S., Jr. Zalesny; Don Riemenschneider; Edmund Bauer

    2000-01-01

    We studied genetic and environmental effects on adventitious root initiation and growth because rooting is biologically prerequisite to the establishment of hybrid poplar plantations. Six clones from two pedigrees (pure Populus deltoides "cottonwoods" and P. deltoides x P. maximowiczii hybrids) were...

  13. An integrated socioeconomic analysis of innovation adoption : The case of hybrid cocoa in Ghana

    NARCIS (Netherlands)

    Boahene, K.; Snijders, T.A.B.; Folmer, H.

    1999-01-01

    This study employs a multidisciplinary model to explain the adoption of agricultural innovations in developing economies with reference to hybrid cocoa in Ghana. The empirical evidence shows that, in the adoption of hybrid cocoa, the support that small-scale farmers obtain via their social networks

  14. Hybrid composites - State-of-the-art review: Analysis, design, application and fabrication

    Science.gov (United States)

    Chamis, C. C.; Lark, R. F.

    1977-01-01

    The review covers hybrid composites that consist of two or more different types of fibers (or fiber composites) in a frequently repeated pattern in a laminate. The fibers considered are boron, graphite, glass, and Kevlar; the resins considered include mostly structural epoxies, with some utilization of polyimides and thermoplastics. The review shows that considerable data have been generated for the tensile strength properties, as well as tensile and thermal fatigue, of interply hybrids, and for the impact resistance of interply and intraply hybrids. The rule of mixtures appears to be adequate for predicting longitudinal and transverse mechanical properties of unidirectional interply hybrids, and linear laminate theory appears to be adequate for predicting the elastic response of hybrids.

  15. DNA sequence analysis by hybridization with oligonucleotide microchips : MALDI mass spectrometry identification of 5mers contiguously stacked to microchip oligonucleotides.

    Energy Technology Data Exchange (ETDEWEB)

    Stomakhin, A. A.; Vasiliskov, V. A.; Timofeev, E.; Schulga, D.; Cotter, R. J.; Mirzabekov, A. D.; Biochip Technology Center; Engelhardt Inst. of Molecular Biology; Moscow Inst. of Physics and Technology; Middle Atlantic Mass Spectrometry Lab.; Johns Hopkins Univ. School of Medicine

    2000-01-01

    Matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) has been applied to increase the informational output from DNA sequence analysis. It has been used to analyze DNA by hybridization with microarrays of gel-immobilized oligonucleotides extended with stacked 5mers. In model experiments, a 28 nt long DNA fragment was hybridized with 10 immobilized, overlapping 8mers. Then, in a second round of hybridization DNA-8mer duplexes were hybridized with a mixture of 10 5mers. The stability of the 5mer complex with DNA was increased to raise the melting temperature of the duplex by 10-15{sup o}C as a result of stacking interaction with 8mers. Contiguous 13 bp duplexes containing an internal break were formed. MALDI MS identified one or, in some cases, two 5mers contiguously stacked to each DNA-8mer duplex formed on the microchip. Incorporating a mass label into 5mers optimized MALDI MS monitoring. This procedure enabled us to reconstitute the sequence of a model DNA fragment and identify polymorphic nucleotides. The application of MALDI MS identification of contiguously stacked 5mers to increase the length of DNA for sequence analysis is discussed.

  16. Proteomic analysis of heterosis in the leaves of sorghum-sudangrass hybrids.

    Science.gov (United States)

    Han, Pingan; Lu, Xiaoping; Mi, Fugui; Dong, Jing; Xue, Chunlei; Li, Jianke; Han, Bin; Zhang, Xiaoyu

    2016-02-01

    Sorghum-sudangrass hybrids are widely used for forage and silage in the animal husbandry industry due to their hardiness. The heterozygous first generation of sorghum-sudangrass hybrids displays performance superior to their homozygous, parental inbred lines. In order to study the molecular details underlying its heterosis, the leaves of sorghum-sudangrass hybrids and their parents were compared using mass spectrometry-based proteomics. Results showed that among the 996 proteins that were identified, 32 proteins showed 'additive accumulation expression patterns', indicating that the protein abundance in sorghum-sudangrass hybrids showed no significant difference from the average of their parents. Additionally, 74 proteins showed 'nonadditive accumulation expression patterns' (the proteins abundance in the hybrids showed significant difference from the average of their parents). Both additive and nonadditive proteins were mainly involved in photosynthesis and carbohydrate metabolism. More upregulated additive and nonadditive proteins were in the hybrids than in their parents, suggesting that additive and nonadditive proteins are essential to the vigor of sorghum-sudangrass hybrids. The nonadditive proteins were enriched in photosynthesis, carbohydrate metabolism, and protein oligomerization, but the additive proteins were not enriched in any pathway, which indicated that the nonadditive proteins could be greater contributors to heterosis than additive proteins. Furthermore, the highly activated photosynthetic pathway in nonadditive proteins implies that photosynthesis in hybrids is heightened to assimilate more organic matter, resulting in an increased yield. Our results provide a proof-of-concept that reveals the molecular components of heterosis in sorghum-sudangrass hybrid leaves and serves as an important step for future genetic manipulation of specific proteins to improve the performance of hybrids.

  17. "Antelope": a hybrid-logic model checker for branching-time Boolean GRN analysis

    Directory of Open Access Journals (Sweden)

    Arellano Gustavo

    2011-12-01

    Full Text Available Abstract Background In Thomas' formalism for modeling gene regulatory networks (GRNs, branching time, where a state can have more than one possible future, plays a prominent role. By representing a certain degree of unpredictability, branching time can model several important phenomena, such as (a asynchrony, (b incompletely specified behavior, and (c interaction with the environment. Introducing more than one possible future for a state, however, creates a difficulty for ordinary simulators, because infinitely many paths may appear, limiting ordinary simulators to statistical conclusions. Model checkers for branching time, by contrast, are able to prove properties in the presence of infinitely many paths. Results We have developed Antelope ("Analysis of Networks through TEmporal-LOgic sPEcifications", http://turing.iimas.unam.mx:8080/AntelopeWEB/, a model checker for analyzing and constructing Boolean GRNs. Currently, software systems for Boolean GRNs use branching time almost exclusively for asynchrony. Antelope, by contrast, also uses branching time for incompletely specified behavior and environment interaction. We show the usefulness of modeling these two phenomena in the development of a Boolean GRN of the Arabidopsis thaliana root stem cell niche. There are two obstacles to a direct approach when applying model checking to Boolean GRN analysis. First, ordinary model checkers normally only verify whether or not a given set of model states has a given property. In comparison, a model checker for Boolean GRNs is preferable if it reports the set of states having a desired property. Second, for efficiency, the expressiveness of many model checkers is limited, resulting in the inability to express some interesting properties of Boolean GRNs. Antelope tries to overcome these two drawbacks: Apart from reporting the set of all states having a given property, our model checker can express, at the expense of efficiency, some properties that ordinary

  18. Analysis on Electric Field Around HVAC-HVDC Hybrid Transmission Lines%Analysis on Electric Field Around HVAC-HVDC Hybrid Transmission Lines

    Institute of Scientific and Technical Information of China (English)

    LI Qian; LIU Jun-xiang; LI Hua; LIN Fu-chang

    2011-01-01

    As the transmission line corridors become more and more rare in China, it is now inevitable for people to construct HVAC-HVDC hybrid transmission lines. The research on the electric field around the transmission lines plays an important role in evaluating the electromagnetic environment nearby. However, few existing research now considered the mutual effect of HVAC-HVDC hybrid transmission lines. Thus, this research designed a program based on windows, which calculated the surface voltage gradient on the transmission lines and the electric field at ground level respectively. This research calculated the surface voltage gradient on the transmission lines by applying the improved method of successive images. For the electric field at ground level under AC transmission line, simula- tion charge method is used, while for the electric field at the ground level under DC transmission lines, deutsch as- sumption method is used. Comparing the results generated by the calculation with those in published literature, the program is reliable. Taking 500 kV transmission lines as an example, when considering the mutual effect of the HVAC-HVDC'lines, the amplitude of the surface voltage gradient will increase by about 10% and the amplitude of the electric field at ground level will increase by about 8%, making the mutual effect of the AC and DC lines unneglectable. Larger part of the electric field at ground level under hybrid lines is produced by the DC line. Thus, in order to control the electric field at ground level under hybrid lines, it should pay more attention on that produced by the DC line.

  19. Comparative proteomic analysis of embryos between a maize hybrid and its parental lines during early stages of seed germination.

    Directory of Open Access Journals (Sweden)

    Baojian Guo

    Full Text Available In spite of commercial use of heterosis in agriculture, the molecular basis of heterosis is poorly understood. It was observed that maize hybrid Zong3/87-1 exhibited an earlier onset or heterosis in radicle emergence. To get insights into the underlying mechanism of heterosis in radicle emergence, differential proteomic analysis between hybrid and its parental lines was performed. In total, the number of differentially expressed protein spots between hybrid and its parental lines in dry and 24 h imbibed seed embryos were 134 and 191, respectively, among which 47.01% (63/134 and 34.55% (66/191 protein spots displayed nonadditively expressed pattern. Remarkably, 54.55% of nonadditively accumulated proteins in 24 h imbibed seed embryos displayed above or equal to the level of the higher parent patterns. Moreover, 155 differentially expressed protein spots were identified, which were grouped into eight functional classes, including transcription & translation, energy & metabolism, signal transduction, disease & defense, storage protein, transposable element, cell growth & division and unclassified proteins. In addition, one of the upregulated proteins in F1 hybrids was ZmACT2, a homolog of Arabidopsis thaliana ACT7 (AtACT7. Expressing ZmACT2 driven by the AtACT7 promoter partially complemented the low germination phenotype in the Atact7 mutant. These results indicated that hybridization between two parental lines can cause changes in the expression of a variety of proteins, and it is concluded that the altered pattern of gene expression at translational level in the hybrid may be responsible for the observed heterosis.

  20. Genetic Diversity among Parents of Hybrid Rice Based on Cluster Analysis of Morphological Traits and Simple Sequence Repeat Markers

    Institute of Scientific and Technical Information of China (English)

    WANG Sheng-jun; LU Zuo-mei; WAN Jian-min

    2006-01-01

    The genetic diversity of 41 parental lines popularized in commercial hybrid rice production in China was studied by using cluster analysis of morphological traits and simple sequence repeat (SSR) markers. Forty-one entries were assigned into two clusters (I.e. Early or medium-maturing cluster; medium or late-maturing cluster) and further assigned into six sub-clusters based on morphological trait cluster analysis. The early or medium-maturing cluster was composed of 15 maintainer lines, four early-maturing restorer lines and two thermo-sensitive genic male sterile lines, and the medium or late-maturing cluster included 16 restorer lines and 4 medium or late-maturing maintainer lines. Moreover, the SSR cluster analysis classified 41 entries into two clusters (I.e. Maintainer line cluster and restorer line cluster) and seven sub-clusters. The maintainer line cluster consisted of all 19 maintainer lines, two thermo-sensitive genic male sterile lines, while the restorer line cluster was composed of all 20 restorer lines. The SSR analysis fitted better with the pedigree information. From the views on hybrid rice breeding, the results suggested that SSR analysis might be a better method to study the diversity of parental lines in indica hybrid rice.

  1. Inverse Thermal Analysis of Alloy 690 Laser and Hybrid Laser-GMA Welds Using Solidification-Boundary Constraints

    Science.gov (United States)

    Lambrakos, S. G.

    2017-08-01

    An inverse thermal analysis of Alloy 690 laser and hybrid laser-GMA welds is presented that uses numerical-analytical basis functions and boundary constraints based on measured solidification cross sections. In particular, the inverse analysis procedure uses three-dimensional constraint conditions such that two-dimensional projections of calculated solidification boundaries are constrained to map within experimentally measured solidification cross sections. Temperature histories calculated by this analysis are input data for computational procedures that predict solid-state phase transformations and mechanical response. These temperature histories can be used for inverse thermal analysis of welds corresponding to other welding processes whose process conditions are within similar regimes.

  2. Genetic Analysis of Heterosis for Number of Spikelets per Panicle and Panicle Length of F1 Hybrids in japonica Rice Hybrids

    Institute of Scientific and Technical Information of China (English)

    ZHU Xu-dong; HONG De-Lin; SHEN Ying; LENG Yan; Henri ADREIT; Julien FROUIN; Didier HARREAU

    2004-01-01

    Genetic analysis of heterosis for number of spikelets per panicle and panicle length of F1 hybrid was conducted by using japonica rice varieties Bing 8979, C Bao, their F1, F2 and triple test cross (TTC) progenies. The two traits, panicle length and number of spikelets per panicle were controlled by polygenes, which were dispersed in the two parents. The dispersion of these polygenes was the genetic basis for the heterosis. Genetic variation in panicle length was mainly due to additive and dominant effects, and the dominant component played a determinative role. For number of spikelets per panicle, the effect of non-allelic genes was highly significant (1% probability level), and there existed epistasis including effects of additive × additive, additive×dominant, and dominant × dominant.

  3. GISH Analysis of Subsequent Progeny Crossed with 2n-gametes of F-1 Oriental-Asiatic Interspecific Hybrid in Lily

    NARCIS (Netherlands)

    Chung, M.Y.; Chung, J.D.; Tuyl, van J.M.; Lim, K.B.

    2009-01-01

    This study was carried out to analyze the chromosome composition and homoeologous recombination of subsequent progenies, derived from cross of Oriental-Asiatic (OA) interspecific hybrid producing 2n-gametes, by GISH technique. GISH analysis of F-1 OA interspecific hybrid '2nOA-001', which produced 2

  4. Significance of Dynamic and Transient Analysis in the Design and Operation of Hybrid Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Panwar, Mayank; Mohanpurkar, Manish; Hovsapian, Rob; Osorio, Julian D.

    2015-02-01

    Energy systems were historically designed and operated with a specific energy conversion objective, while managing loads and resources. In the recent years, the increased utilization of non-dispatchable renewable sources such as wind and solar has played a role in power quality and the reliability of power systems. In order to mitigate the risk associated with the non-dispatchable resources an integrated approach, such as Hybrid Energy Systems (HES), has to be taken, integrating the loads and resource management between the traditional thermal power plants and the non-dispatchable resources. As our electric energy becomes more diverse in its generation resources, the HES with its operational control system, its real-time view and its dynamic decisions making will become an essential part of the integrated energy systems and improve the overall grid reliability. The operational constraints of the energy sources on both the thermal power plants and the non-dispatchable resources in HES, plays a vital role in the planning and design stage. It is an established fact that the choice of energy source depends on the available natural resources and possible infrastructure. A critical component of decision-making depends on the complementary nature and controllability of the energy sources to supply the load demands with high reliability. Controllability of complex HES to achieve desired performance and flexibility is implemented via coordinated control systems while simultaneously generating electricity and other useful products such as useful heat or hydrogen. These systems are based on instrumentation, signal processing, control theory, and engineering system design. The entire HES along with the control systems are characterized by widely varying time constants. Hence, for a well-coordinated control and operation, we propose physics based modeling of the subsystems to assist in a dynamic and transient analysis. Dynamic and transient analysis in real and non-real time

  5. Array comparative genomic hybridization analysis of Trichoderma reesei strains with enhanced cellulase production properties

    Directory of Open Access Journals (Sweden)

    Penttilä Merja

    2010-07-01

    Full Text Available Abstract Background Trichoderma reesei is the main industrial producer of cellulases and hemicellulases that are used to depolymerize biomass in a variety of biotechnical applications. Many of the production strains currently in use have been generated by classical mutagenesis. In this study we characterized genomic alterations in high-producing mutants of T. reesei by high-resolution array comparative genomic hybridization (aCGH. Our aim was to obtain genome-wide information which could be utilized for better understanding of the mechanisms underlying efficient cellulase production, and would enable targeted genetic engineering for improved production of proteins in general. Results We carried out an aCGH analysis of four high-producing strains (QM9123, QM9414, NG14 and Rut-C30 using the natural isolate QM6a as a reference. In QM9123 and QM9414 we detected a total of 44 previously undocumented mutation sites including deletions, chromosomal translocation breakpoints and single nucleotide mutations. In NG14 and Rut-C30 we detected 126 mutations of which 17 were new mutations not documented previously. Among these new mutations are the first chromosomal translocation breakpoints identified in NG14 and Rut-C30. We studied the effects of two deletions identified in Rut-C30 (a deletion of 85 kb in the scaffold 15 and a deletion in a gene encoding a transcription factor on cellulase production by constructing knock-out strains in the QM6a background. Neither the 85 kb deletion nor the deletion of the transcription factor affected cellulase production. Conclusions aCGH analysis identified dozens of mutations in each strain analyzed. The resolution was at the level of single nucleotide mutation. High-density aCGH is a powerful tool for genome-wide analysis of organisms with small genomes e.g. fungi, especially in studies where a large set of interesting strains is analyzed.

  6. Detection and Analysis of DNA Hybridization Characteristics by using Thermodynamic Method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D.K.; Kwon, Y.S. [Donga University, Pusan (Korea)

    2002-06-01

    The determination of DNA hybridization reaction can apply the molecular biology research, clinic diagnostics, bioengineering, environment monitoring, food science and application area. So, the improvement of DNA hybridization detection method is very important for the determination of this hybridization reaction. Several molecular biological techniques require accurate predictions of matched versus mismatched hybridization thermodynamics, such as PCR, sequencing by hybridization, gene diagnostics and antisense oligonucleotide probes. In addition, recent developments of oligonucleotide chip arrays as means for biochemical assays and DNA sequencing requires accurate knowledge of hybridization thermodynamics and population ratios at matched and mismatched target sites. In this study, we report the characteristics of the probe and matched, mismatched target oligonucleotide hybridization reaction using thermodynamic method. Thermodynamic of 5 oligonucleotides with central and terminal mismatch sequences were obtained by measured UV-absorbance as a function of temperature. The data show that the nearest-neighbor base-pair model is adequate for predicting thermodynamics of oligonucleotides with average deviations for {delta}H{sup O}, {delta}S{sup O}, {delta}G{sub 37}{sup O} and T{sub m}, respectively. (author). 6 refs., 4 figs., 5 tabs.

  7. Formation of diploid and triploid hybrid groupers (hybridization of Epinephelus coioides ♀ × Epinephelus lanceolatus ♂) and their 5S gene analysis.

    Science.gov (United States)

    Huang, Wen; Qin, Qinbo; Yang, Huirong; Li, Shuisheng; Hu, Chaoqun; Wang, Yude; Zhang, Yong; Liu, Shaojun; Lin, Haoran

    2016-10-07

    Interspecies hybridization is widely used to achieve heterosis or hybrid vigor, which has been observed and harnessed by breeders for centuries. Natural allopolyploid hybrids generally exhibit more superior heterosis than both the diploid progenies and their parental species. However, polyploid formation processes have been long ignored, the genetic basis of heterosis in polyploids remains elusive. In the present study, triploid hybrids had been demonstrated to contain two sets of chromosomes from mother species and one set from father species. Cellular polyploidization process in the embryos had been traced. The triploid hybrids might be formed by failure formation of the second polarized genome during the second meiosis stage. Four spindle centers were observed in anaphase stage of the first cell division. Three spindle centers were observed in side of cell plate after the first cell division. The 5S rDNA genes of four types of groupers were cloned and analyzed. The diploid and triploid hybrids had been proved to contain the tandem chimera structures which were recombined by maternal and paternal monomer units. The results indicated that genome re-fusion had occurred in the hybrid progenies. To further elucidate the genetic patterns of diploid and triploid hybrids, fluorescence chromosome location had been carried out, maternal 5S gene (M-386) were used as the probe. The triploid hybrids contained fewer fluorescence loci numbers than the maternal species. The results indicated that participation of paternal 5S gene in the triploid hybrid genome had degraded the match rates of M-386 probe. Our study is the first to investigate the cellular formation processes of natural allopolyploids in hybrid fish, the cellular polyploidization process may be caused by failure formation of the second polarized genome during the meiosis, and our results will provide the molecular basis of hybrid vigor in interspecies hybridization.

  8. Needle morphological evidence of the homoploid hybrid origin of Pinus densata based on analysis of artificial hybrids and the putative parents, Pinus tabuliformis and Pinus yunnanensis.

    Science.gov (United States)

    Xing, Fangqian; Mao, Jian-Feng; Meng, Jingxiang; Dai, Jianfeng; Zhao, Wei; Liu, Hao; Xing, Zhen; Zhang, Hua; Wang, Xiao-Ru; Li, Yue

    2014-05-01

    Genetic analyses indicate that Pinus densata is a natural homoploid hybrid originating from Pinus tabuliformis and Pinus yunnanensis. Needle morphological and anatomical features show relative species stability and can be used to identify coniferous species. Comparative analyses of these needle characteristics and phenotypic differences between the artificial hybrids, P. densata, and parental species can be used to determine the genetic and phenotypic evolutionary consequences of natural hybridization. Twelve artificial hybrid families, the two parental species, and P. densata were seeded in a high-altitude habitat in Linzhi, Tibet. The needles of artificial hybrids and the three pine species were collected, and 24 needle morphological and anatomical traits were analyzed. Based on these results, variations in 10 needle traits among artificial hybrid families and 22 traits among species and artificial hybrids were predicted and found to be under moderate genetic control. Nineteen needle traits in artificial hybrids were similar to those in P. densata and between the two parental species, P. tabuliformis and P. yunnanensis. The ratio of plants with three needle clusters in artificial hybrids was 22.92%, which was very similar to P. densata. The eight needle traits (needle length, the mean number of stomata in sections 2 mm in length of the convex and flat sides of the needle, mean stomatal density, mesophyll/vascular bundle area ratio, mesophyll/resin canal area ratio, mesophyll/(resin canals and vascular bundles) area ratio, vascular bundle/resin canal area ratio) relative to physiological adaptability were similar to the artificial hybrids and P. densata. The similar needle features between the artificial hybrids and P. densata could be used to verify the homoploid hybrid origin of P. densata and helps to better understand of the hybridization roles in adaptation and speciation in plants.

  9. Optimum Design and Analysis of Axial Hybrid Magnetic Bearings Using Multi-Objective Genetic Algorithms

    Science.gov (United States)

    Rao, J. S.; Tiwari, R.

    2012-01-01

    Design optimization of axial hybrid magnetic thrust bearings (with bias magnets) was carried out using multi-objective evolutionary algorithms (MOEAs) and compared with the case of electromagnetic bearings (without bias magnets). Mathematical models of objective functions and associated constraints are presented and discussed. The different aspects of implemented MOEA are discussed. It is observed that the size of the bearing with bias magnets is considerably reduced as compared to the case of those without bias magnets, with the objective function as the minimization of weight for the same operating conditions. Similarly, current densities aret reduced drastically with biased magnets when the objective function is chosen as the minimization of the power loss. For illustration of various performances of the bearing, a typical design has been chosen from the final optimized population by an "a posteriori" approach. Sensitivities for both the objective functions with respect to the outer radius, the inner radius, and the height of coil are observed to be approximately in the ratio 2.5:1.6:1. Analysis of final optimized population has been carried out and is compared with the case without bias magnets and some salient points are observed in the case of using bias magnets.

  10. Performance and delay analysis of hybrid ARQ with incremental redundancy over double rayleigh fading channels

    KAUST Repository

    Chelli, Ali

    2014-11-01

    In this paper, we study the performance of hybrid automatic repeat request (HARQ) with incremental redundancy over double Rayleigh channels, a common model for the fading amplitude of vehicle-to-vehicle communication systems. We investigate the performance of HARQ from an information theoretic perspective. Analytical expressions are derived for the \\\\epsilon-outage capacity, the average number of transmissions, and the average transmission rate of HARQ with incremental redundancy assuming a maximum number of HARQ rounds. Moreover, we evaluate the delay experienced by Poisson arriving packets for HARQ with incremental redundancy. We provide analytical expressions for the expected waiting time, the packet\\'s sojourn time in the queue, the average consumed power, and the energy efficiency. In our study, the communication rate per HARQ round is adjusted to the average signal-to-noise ratio (SNR) such that a target outage probability is not exceeded. This setting conforms with communication systems in which a quality of service is expected regardless of the channel conditions. Our analysis underscores the importance of HARQ in improving the spectral efficiency and reliability of communication systems. We demonstrate as well that the explored HARQ scheme achieves full diversity. Additionally, we investigate the tradeoff between energy efficiency and spectral efficiency.

  11. [Development of New Mathematical Methodology in Air Traffic Control for the Analysis of Hybrid Systems

    Science.gov (United States)

    Hermann, Robert

    1997-01-01

    The aim of this research is to develop new mathematical methodology for the analysis of hybrid systems of the type involved in Air Traffic Control (ATC) problems. Two directions of investigation were initiated. The first used the methodology of nonlinear generalized functions, whose mathematical foundations were initiated by Colombeau and developed further by Oberguggenberger; it has been extended to apply to ordinary differential. Systems of the type encountered in control in joint work with the PI and M. Oberguggenberger. This involved a 'mixture' of 'continuous' and 'discrete' methodology. ATC clearly involves mixtures of two sorts of mathematical problems: (1) The 'continuous' dynamics of a standard control type described by ordinary differential equations (ODE) of the form: {dx/dt = f(x, u)} and (2) the discrete lattice dynamics involved of cellular automata. Most of the CA literature involves a discretization of a partial differential equation system of the type encountered in physics problems (e.g. fluid and gas problems). Both of these directions requires much thinking and new development of mathematical fundamentals before they may be utilized in the ATC work. Rather than consider CA as 'discretization' of PDE systems, I believe that the ATC applications will require a completely different and new mathematical methodology, a sort of discrete analogue of jet bundles and/or the sheaf-theoretic techniques to topologists. Here too, I have begun work on virtually 'virgin' mathematical ground (at least from an 'applied' point of view) which will require considerable preliminary work.

  12. Design,analysis and control of hybrid excited doubly salient stator-permanent-magnet motor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper,a new hybrid excited doubly salient stator-permanent-magnet motor is proposed,where both permanent magnets and DC field windings are located in the stator.In theory,the mathematical model and design method of the motor are developed.The corresponding output power equation and the relationship between the flux control capability and the extended speed range are deduced in details.By using an efficient "one-step" three-dimensional(3D) finite element method,the electromagnetic performances are analyzed,in which the leakage flux outside the stator circumference and end-effect are taken into account.Based on the operation principle of the motor,the control strategy and scheme are developed and implemented experimentally.Both experimental results and finite element analysis show that the proposed motor not only maintains the advantages of doubly salient permanent magnet motors,but also offers high energy efficiency over a wide speed range,which makes the motor an interesting candidate for electric vehicles.

  13. Suppression subtractive hybridization and comparative expression analysis to identify developmentally regulated genes in filamentous fungi.

    Science.gov (United States)

    Gesing, Stefan; Schindler, Daniel; Nowrousian, Minou

    2013-09-01

    Ascomycetes differentiate four major morphological types of fruiting bodies (apothecia, perithecia, pseudothecia and cleistothecia) that are derived from an ancestral fruiting body. Thus, fruiting body differentiation is most likely controlled by a set of common core genes. One way to identify such genes is to search for genes with evolutionary conserved expression patterns. Using suppression subtractive hybridization (SSH), we selected differentially expressed transcripts in Pyronema confluens (Pezizales) by comparing two cDNA libraries specific for sexual and for vegetative development, respectively. The expression patterns of selected genes from both libraries were verified by quantitative real time PCR. Expression of several corresponding homologous genes was found to be conserved in two members of the Sordariales (Sordaria macrospora and Neurospora crassa), a derived group of ascomycetes that is only distantly related to the Pezizales. Knockout studies with N. crassa orthologues of differentially regulated genes revealed a functional role during fruiting body development for the gene NCU05079, encoding a putative MFS peptide transporter. These data indicate conserved gene expression patterns and a functional role of the corresponding genes during fruiting body development; such genes are candidates of choice for further functional analysis.

  14. Construction and analysis of a suppression subtractive hybridization library of regeneration-related genes in soybean.

    Science.gov (United States)

    Sun, J; Li, J; Liu, M; Zhang, B B; Li, D M; Wang, M; Zhang, C; Li, W B; Su, A Y; Wu, X X

    2015-01-30

    The development of a genetic transformation system is needed to address the problem of the low efficiency associated with soybean regeneration. To contribute to the enhancement of the soybean regenerative capacity, we explored the developmental mechanisms of soybean regeneration at the molecular level using a suppression subtractive hybridization cDNA library constructed from cotyledonary nodes of soybean cultivar DN50. A total of 918 positive clones were identified and screened, with most inserted fragments ranging from 100 to 750 bp. Of these, 411 differentially expressed functional expressed sequence tags were identified and annotated based on their similarity to orthologs and paralogs detected in GenBank using the nucleotide and translated nucleotide Basic Local Alignment Search Tools. Functional analysis revealed that the associated genes were involved in signal transduction, synthesis, and metabolism of macromolecules, glucose and protein synthesis and metabolism, light and leaf morphogenesis, regulation of apoptosis, cell defense, cell wall differentiation, and a variety of hormone and cytokinin-mediated signaling pathways. The information uncovered in our study should serve as a foundation for the establishment of an efficient and stable genetic transformation system for soybean regeneration.

  15. Analysis of gene expression in granulosa cells of ovine antral growing follicles using suppressive subtractive hybridization.

    Science.gov (United States)

    Chen, A Qin; Wang, Zheng Guang; Xu, Zi Rong; Yu, Song Dong; Yang, Zhi Gang

    2009-10-01

    Follicular growth, development and ovulation are highly ordered processes that involve the expression of many genes under precise temporal and spatial regulation. However, information on stage-specific gene expression during the antral follicle phase in sheep is not well understood. In the present study, suppressive subtractive hybridization (SSH) was performed to screen genes that were differentially expressed in the granulosa cells between large follicles (LF, >5mm) and small follicles (SF, 3-5mm), and subtractive cDNA library was constructed. Furthermore, with dot-blot analysis, a total of 90 clones randomly selected from the library were proven to be differentially expressed in the granulosa cells. Among these, 38 exhibited high homology to known genes, 14 sequences were corresponding to novel expressed sequence tags (ESTs). Four ESTs, LAPTM4A, SERPINE2, GSTA1, and INHBA, were further examined the reproducibility of the SSH data by the real-time quantitative PCR. Results confirmed an increase expression of respective mRNA in granulosa cells of large follicles compared with that of small follicles. It is concluded that we have identified several genes (known or unknown) that may effect follicular growth, dominance or ovulation in ewes.

  16. Optoelectronic Evaluation and Loss Analysis of PEDOT:PSS/Si Hybrid Heterojunction Solar Cells.

    Science.gov (United States)

    Yang, Zhenhai; Fang, Zebo; Sheng, Jiang; Ling, Zhaoheng; Liu, Zhaolang; Zhu, Juye; Gao, Pingqi; Ye, Jichun

    2017-12-01

    The organic/silicon (Si) hybrid heterojunction solar cells (HHSCs) have attracted considerable attention due to their potential advantages in high efficiency and low cost. However, as a newly arisen photovoltaic device, its current efficiency is still much worse than commercially available Si solar cells. Therefore, a comprehensive and systematical optoelectronic evaluation and loss analysis on this HHSC is therefore highly necessary to fully explore its efficiency potential. Here, a thoroughly optoelectronic simulation is provided on a typical planar polymer poly (3,4-ethylenedioxy thiophene):polystyrenesulfonate (PEDOT:PSS)/Si HHSC. The calculated spectra of reflection and external quantum efficiency (EQE) match well with the experimental results in a full-wavelength range. The losses in current density, which are contributed by both optical losses (i.e., reflection, electrode shield, and parasitic absorption) and electrical recombination (i.e., the bulk and surface recombination), are predicted via carefully addressing the electromagnetic and carrier-transport processes. In addition, the effects of Si doping concentrations and rear surface recombination velocities on the device performance are fully investigated. The results drawn in this study are beneficial to the guidance of designing high-performance PEDOT:PSS/Si HHSCs.

  17. Automatic aerial image shadow detection through the hybrid analysis of RGB and HIS color space

    Science.gov (United States)

    Wu, Jun; Li, Huilin; Peng, Zhiyong

    2015-12-01

    This paper presents our research on automatic shadow detection from high-resolution aerial image through the hybrid analysis of RGB and HIS color space. To this end, the spectral characteristics of shadow are firstly discussed and three kinds of spectral components including the difference between normalized blue and normalized red component - BR, intensity and saturation components are selected as criterions to obtain initial segmentation of shadow region (called primary segmentation). After that, within the normalized RGB color space and HIS color space, the shadow region is extracted again (called auxiliary segmentation) using the OTSU operation, respectively. Finally, the primary segmentation and auxiliary segmentation are combined through a logical AND-connection operation to obtain reliable shadow region. In this step, small shadow areas are removed from combined shadow region and morphological algorithms are apply to fill small holes as well. The experimental results show that the proposed approach can effectively detect the shadow region from high-resolution aerial image and in high degree of automaton.

  18. Stability Analysis of a Hybrid Cellular Automaton Model of Cell Colony Growth

    CERN Document Server

    Gerlee, P

    2007-01-01

    Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell colony growth. In the model the growth of the colony is limited by a nutrient that is consumed by the cells and which inhibits cell division if it falls below a certain threshold. Using this model we have investigated how the nutrient consumption rate of the cells affects the growth dynamics of the colony. We found that for low consumption rates the colony takes on a Eden-like morphology, while for higher consumption rates the morphology of the colony is branched with a fractal geometry. These findings are in agreement with previous results, but the simplicity of the model presented here allows for a linear stability analysis of the system. By observing that the local growth of the colony is proportional to the flux of the nutrient we derive an approximate dispersion relation fo...

  19. Optoelectronic Evaluation and Loss Analysis of PEDOT:PSS/Si Hybrid Heterojunction Solar Cells

    Science.gov (United States)

    Yang, Zhenhai; Fang, Zebo; Sheng, Jiang; Ling, Zhaoheng; Liu, Zhaolang; Zhu, Juye; Gao, Pingqi; Ye, Jichun

    2017-01-01

    The organic/silicon (Si) hybrid heterojunction solar cells (HHSCs) have attracted considerable attention due to their potential advantages in high efficiency and low cost. However, as a newly arisen photovoltaic device, its current efficiency is still much worse than commercially available Si solar cells. Therefore, a comprehensive and systematical optoelectronic evaluation and loss analysis on this HHSC is therefore highly necessary to fully explore its efficiency potential. Here, a thoroughly optoelectronic simulation is provided on a typical planar polymer poly (3,4-ethylenedioxy thiophene):polystyrenesulfonate (PEDOT:PSS)/Si HHSC. The calculated spectra of reflection and external quantum efficiency (EQE) match well with the experimental results in a full-wavelength range. The losses in current density, which are contributed by both optical losses (i.e., reflection, electrode shield, and parasitic absorption) and electrical recombination (i.e., the bulk and surface recombination), are predicted via carefully addressing the electromagnetic and carrier-transport processes. In addition, the effects of Si doping concentrations and rear surface recombination velocities on the device performance are fully investigated. The results drawn in this study are beneficial to the guidance of designing high-performance PEDOT:PSS/Si HHSCs.

  20. Reduced Fracture Finite Element Model Analysis of an Efficient Two-Scale Hybrid Embedded Fracture Model

    KAUST Repository

    Amir, Sahar Z.

    2017-06-09

    A Hybrid Embedded Fracture (HEF) model was developed to reduce various computational costs while maintaining physical accuracy (Amir and Sun, 2016). HEF splits the computations into fine scale and coarse scale. Fine scale solves analytically for the matrix-fracture flux exchange parameter. Coarse scale solves for the properties of the entire system. In literature, fractures were assumed to be either vertical or horizontal for simplification (Warren and Root, 1963). Matrix-fracture flux exchange parameter was given few equations built on that assumption (Kazemi, 1968; Lemonnier and Bourbiaux, 2010). However, such simplified cases do not apply directly for actual random fracture shapes, directions, orientations …etc. This paper shows that the HEF fine scale analytic solution (Amir and Sun, 2016) generates the flux exchange parameter found in literature for vertical and horizontal fracture cases. For other fracture cases, the flux exchange parameter changes according to the angle, slop, direction, … etc. This conclusion rises from the analysis of both: the Discrete Fracture Network (DFN) and the HEF schemes. The behavior of both schemes is analyzed with exactly similar fracture conditions and the results are shown and discussed. Then, a generalization is illustrated for any slightly compressible single-phase fluid within fractured porous media and its results are discussed.

  1. Proton and Helium Injection Into First Order Fermi Acceleration at Shocks: Hybrid Simulation and Analysis

    Science.gov (United States)

    Dudnikova, Galina; Malkov, Mikhail; Sagdeev, Roald; Liseykina, Tatjana; Hanusch, Adrian

    2016-10-01

    Elemental composition of galactic cosmic rays (CR) probably holds the key to their origin. Most likely, they are accelerated at collisionless shocks in supernova remnants, but the acceleration mechanism is not entirely understood. One complicated problem is ``injection'', a process whereby the shock selects a tiny fraction of particles to keep on crossing its front and gain more energy. Comparing the injection rates of particles with different mass to charge ratio is a powerful tool for studying this process. Recent advances in measurements of CR He/p ratio have provided particularly important new clues. We performed a series of hybrid simulations and analyzed a joint injection of protons and Helium, in conjunction with upstream waves they generate. The emphasis of this work is on the bootstrap aspects of injection manifested in particle confinement to the shock and, therefore, their continuing acceleration by the self-driven waves. The waves are initially generated by He and protons in separate spectral regions, and their interaction plays a crucial role in particle acceleration. The work is ongoing and new results will be reported along with their analysis and comparison with the latest data from the AMS-02 space-based spectrometer. Work supported Grant RFBR 16-01-00209, NASA ATP-program under Award NNX14AH36G, and by the US Department of Energy under Award No. DE-FG02-04ER54738.

  2. A Hybrid Real-time Zero-day Attack Detection and Analysis System

    Directory of Open Access Journals (Sweden)

    Ratinder Kaur

    2015-08-01

    Full Text Available A zero-day attack poses a serious threat to the Internet security as it exploits zero-day vulnerabilities in the computer systems. Attackers take advantage of the unknown nature of zero-day exploits and use them in conjunction with highly sophisticated and targeted attacks to achieve stealthiness with respect to standard intrusion detection techniques. Thus, it's difficult to defend against such attacks. Present research exhibits various issues and is not able to provide complete solution for the detection and analysis of zero-day attacks. This paper presents a novel hybrid system that integrates anomaly, behavior and signature based techniques for detecting and analyzing zero-day attacks in real-time. It has layered and modular design which helps to achieve high performance, flexibility and scalability. The system is implemented and evaluated against various standard metrics like True Positive Rate (TPR, False Positive Rate (FPR, F-Measure, Total Accuracy (ACC and Receiver Operating Characteristic (ROC curve. The result shows high detection rate with nearly zero false positives. Additionally, the proposed system is compared with Honeynet system.

  3. Dynamic Analysis of a Hybrid Squeeze Film Damper Mounted Rub-Impact Rotor-Stator System

    Directory of Open Access Journals (Sweden)

    Cai-Wan Chang-Jian

    2012-01-01

    Full Text Available An investigation is carried out on the systematic analysis of the dynamic behavior of the hybrid squeeze-film damper (HSFD mounted a rotor-bearing system with strongly nonlinear oil-film force and nonlinear rub-impact force in the present study. The dynamic orbits of the system are observed using bifurcation diagrams plotted using the dimensionless rotating speed ratio as control parameters. The onset of chaotic motion is identified from the phase diagrams, power spectra, Poincaré maps, bifurcation diagrams, maximum Lyapunov exponents, and fractal dimension of the rotor-bearing system. The dynamic behaviors are unlike the usual ways into chaos (1⇒2⇒4⇒8⇒16⇒32⋯⇒ chaos or periodic ⇒ quasi-periodic ⇒ chaotic, it suddenly gets in chaos from the periodic motion without any transition. The results presented in this study provide some useful insights into the design and development of a rotor-bearing system for rotating machinery that operates in highly rotating speed and highly nonlinear regimes.

  4. Energy Conservation Analysis and Control of Hybrid Active Semiactive Suspension with Three Regulating Damping Levels

    Directory of Open Access Journals (Sweden)

    Long Chen

    2016-01-01

    Full Text Available Active suspension has not been popularized for high energy consumption. To address this issue, this paper introduces the concept of a new kind of suspension. The linear motor is considered to be integrated into an adjustable shock absorber to form the hybrid active semiactive suspension (HASAS. To realize the superiority of HASAS, its energy consumption and regeneration mechanisms are revealed. And the system controller which is composed of linear quadratic regulator (LQR controller, mode decision and switch controller, and the sliding mode control based thrust controller is developed. LQR controller is designed to maintain the suspension control objectives, while mode decision and switch controller decides the optimal damping level to tune motor thrust. The thrust controller ensures motor thrust tracking. An adjustable shock absorber with three regulating levels to be used in HASAS is trial produced and tested to obtain its working characteristics. Finally, simulation analysis is made with the experimental three damping characteristics. The impacts of adjustable damping on the motor force and energy consumption are investigated. Simulation results demonstrate the advantages of HASAS in energy conservation with various suspension control objectives. Even self-powered active control and energy regenerated to the power source can be realized.

  5. Environmental impact analysis of electric and hybrid vehicle batteries. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-16

    This environmental impact analysis of electric and hybrid vehicle batteries is intended to identify principal environmental impacts resulting directly or indirectly from the development of electric vehicle batteries. Thus, the result of this study could be used to determine the appropriate following step in the U.S. DOE's EIA process. The environmental impacts considered in this document are the incremental impacts generated during the various phases in the battery life cycle. The processes investigated include mining, milling, smelting, and refining of metallic materials for electrode components; manufacturing processes of inorganic chemicals and other materials for electrolytes and other hardware components; battery assembly processes; operation and maintenance of batteries; and recycling and disposal of used batteries. The severity of the incremental impacts is quantified to the extent consistent with the state-of-knowledge. Many of the industrial processes involve proprietary or patent information; thus, in many cases, the associated environmental impacts could not be determined. In addition, most candidate battery systems are still in the development phase. Thus, the manufacturing and recycling processes for most battery systems either have not been developed by industry, or the information is not available. For these cases, the associated environmental impact evaluations could only be qualitative, and the need for further investigations is indicated. 26 figures, 27 tables. (RWR)

  6. The Tower: Modelling, Analysis and Construction of Bending Active Tensile Membrane Hybrid Structures

    DEFF Research Database (Denmark)

    Holden Deleuran, Anders; Schmeck, Michel; Charles Quinn, Gregory

    2015-01-01

    as combining two or more structural concepts and materials together to create a stronger whole. The paper presents the methods used and developed for design, simulation, evaluation and production, as well as the challenges and obstacles to overcome to build a complex hybrid tower structure in an outside......The project is the result of an interdisciplinary research collaboration between CITA, KET and Fibrenamics exploring the design of integrated hybrid structures employing bending active elements and tensile membranes with bespoke material properties and detailing. Hybrid structures are defined here...

  7. A hybrid domain analysis for systems with delays in state and control

    Directory of Open Access Journals (Sweden)

    Razzaghi M.

    2001-01-01

    Full Text Available The solution of time-delay systems is obtained by using a hybrid function. The properties of the hybrid functions consisting of block-pulse functions and Chebyshev polynomials are presented. The method is based upon expanding various time functions in the system as their truncated hybrid functions. The operational matrix of delay is introduced. The operational matrices of integration and delay are utilized to reduce the solution of time-delay systems to the solution of algebraic equations. Illustrative examples are included to demonstrate the validity and applicability of the technique.

  8. Analysis of Performance and Designing of Bi-Quad Filter using Hybrid Signed digit Number System

    Directory of Open Access Journals (Sweden)

    Sugandha Agarwal

    2012-03-01

    Full Text Available Speed of digital arithmetic processor depends mainly on the speed of adders. This paper provides a technique so that we can increase the speed of addition. Hybrid signed digit number representation perform addition in such a way that the carry propagation chain is limited to single digit position and hence are used to speed up arithmetic operation. Also hybrid signed digit reduces the critical path delay by parallelizing. Hybrid signed digit can be appropriate to use, when output is redundant representation.

  9. Hybrid carbon/glass fiber composites: Micromechanical analysis of structure–damage resistance relationships

    DEFF Research Database (Denmark)

    Mishnaevsky, Leon; Dai, Gaoming

    2014-01-01

    A computational study of the effect of microstructure of hybrid carbon/glass fiber composites on their strength is presented. Unit cells with hundreds of randomly located and misaligned fibers of various properties and arrangements are subject to tensile and compression loading, and the evolution...... of fiber damages is analyzed in numerical experiments. The effects of fiber clustering, matrix properties, nanoreinforcement, load sharing rules on the strength and damage resistance of composites are studied. It was observed that hybrid composites under uniform displacement loading might have lower...... strength than pure composites, while the strength of hybrid composites under inform force loading increases steadily with increasing the volume content of carbon fibers....

  10. Investigations of high power laser beam interaction with material by means of hybrid FVM-FEM and digital image correlation methods

    Science.gov (United States)

    Kujawińska, M.; Łapka, P.; Malesa, M.; Malowany, K.; Prasek, M.; Marczak, J.

    2016-12-01

    The paper presents the new approach to the analysis of interaction between a high power laser beam and matter. The method relies on the combined experimental-numerical spatio-temporal analysis of temperature, displacement and strain maps which are generated at a surface of an object illuminated by a high power laser beam. Transient heat transfer numerical simulations were carried out applying the FVM, while the quasi-transient structural analyses were performed with the aid of the FEM. The displacement maps were captured by means of 3D Digital Image Correlation method, and temperature maps were provided by a high speed IR camera. The experimental data are compared to the initial model of laser induced heat transfer in an object and resulting displacements/strains. The first approach to hybrid experimental-numerical method which aims in indirect determination of laser beam profile is described. The monitoring of displacement/strain maps directly at an illuminated object may be also used for a structural integrity analysis of a target. In the paper at first the numerical simulations applied to model laser beam thermal interaction with solid bodies are presented. Next the laboratory experimental stand is described and the results of the initial tests performed at aluminum and bronze samples are shown and compared with numerical simulations. The advantages and disadvantages of the proposed methodology are discussed in relation to the two applications mentioned above.

  11. A controlled microfluidic electrochemical lab-on-a-chip for label-free diffusion-restricted DNA hybridization analysis.

    Science.gov (United States)

    Ben-Yoav, Hadar; Dykstra, Peter H; Bentley, William E; Ghodssi, Reza

    2015-02-15

    Lab-on-a-chip (LOC) devices for electrochemical analysis of DNA hybridization events offer a technology for real-time and label-free assessment of biomarkers at the point-of-care. Here, we present a microfluidic LOC, with 3 × 3 arrayed electrochemical sensors for the analysis of DNA hybridization events. A new dual layer microfluidic valved manipulation system is integrated providing controlled and automated capabilities for high throughput analysis. This feature improves the repeatability, accuracy, and overall sensing performance (Fig. 1). The electrochemical activity of the fabricated microfluidic device is validated and demonstrated repeatable and reversible Nernstian characteristics. System design required detailed analysis of energy storage and dissipation as our sensing modeling involves diffusion-related electrochemical impedance spectroscopy. The effect of DNA hybridization on the calculated charge transfer resistance and the diffusional resistance components is evaluated. We demonstrate a specific device with an average cross-reactivity value of 27.5%. The device yields semilogarithmic dose response and enables a theoretical detection limit of 1 nM of complementary ssDNA target. This limit is lower than our previously reported non-valved device by 74% due to on-chip valve integration providing controlled and accurate assay capabilities.

  12. The disadvantages of being a hybrid during drought: A combined analysis of plant morphology, physiology and leaf proteome in maize.

    Science.gov (United States)

    Holá, Dana; Benešová, Monika; Fischer, Lukáš; Haisel, Daniel; Hnilička, František; Hniličková, Helena; Jedelský, Petr L; Kočová, Marie; Procházková, Dagmar; Rothová, Olga; Tůmová, Lenka; Wilhelmová, Naďa

    2017-01-01

    A comparative analysis of various parameters that characterize plant morphology, growth, water status, photosynthesis, cell damage, and antioxidative and osmoprotective systems together with an iTRAQ analysis of the leaf proteome was performed in two inbred lines of maize (Zea mays L.) differing in drought susceptibility and their reciprocal F1 hybrids. The aim of this study was to dissect the parent-hybrid relationships to better understand the mechanisms of the heterotic effect and its potential association with the stress response. The results clearly showed that the four examined genotypes have completely different strategies for coping with limited water availability and that the inherent properties of the F1 hybrids, i.e. positive heterosis in morphological parameters (or, more generally, a larger plant body) becomes a distinct disadvantage when the water supply is limited. However, although a greater loss of photosynthetic efficiency was an inherent disadvantage, the precise causes and consequences of the original predisposition towards faster growth and biomass accumulation differed even between reciprocal hybrids. Both maternal and paternal parents could be imitated by their progeny in some aspects of the drought response (e.g., the absence of general protein down-regulation, changes in the levels of some carbon fixation or other photosynthetic proteins). Nevertheless, other features (e.g., dehydrin or light-harvesting protein contents, reduced chloroplast proteosynthesis) were quite unique to a particular hybrid. Our study also confirmed that the strategy for leaving stomata open even when the water supply is limited (coupled to a smaller body size and some other physiological properties), observed in one of our inbred lines, is associated with drought-resistance not only during mild drought (as we showed previously) but also during more severe drought conditions.

  13. Effects of whole-plant corn silage hybrid type on intake, digestion, ruminal fermentation, and lactation performance by dairy cows through a meta-analysis.

    Science.gov (United States)

    Ferraretto, L F; Shaver, R D

    2015-04-01

    Understanding the effect of whole-plant corn silage (WPCS) hybrids in dairy cattle diets may allow for better decisions on hybrid selection by dairy producers, as well as indicate potential strategies for the seed corn industry with regard to WPCS hybrids. Therefore, the objective of this study was to perform a meta-analysis using literature data on the effects of WPCS hybrid type on intake, digestibility, rumen fermentation, and lactation performance by dairy cows. The meta-analysis was performed using a data set of 162 treatment means from 48 peer-reviewed articles published between 1995 and 2014. Hybrids were divided into 3 categories before analysis. Comparative analysis of WPCS hybrid types differing in stalk characteristics were in 4 categories: conventional, dual-purpose, isogenic, or low-normal fiber digestibility (CONS), brown midrib (BMR), hybrids with greater NDF but lower lignin (%NDF) contents or high in vitro NDF digestibility (HFD), and leafy (LFY). Hybrid types differing in kernel characteristics were in 4 categories: conventional or yellow dent (CONG), NutriDense (ND), high oil (HO), and waxy. Genetically modified (GM) hybrids were compared with their genetically similar non-biotech counterpart (ISO). Except for lower lignin content for BMR and lower starch content for HFD than CONS and LFY, silage nutrient composition was similar among hybrids of different stalk types. A 1.1 kg/d greater intake of DM and 1.5 and 0.05 kg/d greater milk and protein yields, respectively, were observed for BMR compared with CONS and LFY. Likewise, DMI and milk yield were greater for HFD than CONS, but the magnitude of the difference was smaller. Total-tract NDF digestibility was greater, but starch digestibility was reduced, for BMR and HFD compared with CONS or LFY. Silage nutrient composition was similar for hybrids of varied kernel characteristics, except for lower CP and EE content for CONG than ND and HO. Feeding HO WPCS to dairy cows decreased milk fat content

  14. Nuclear and mitochondrial DNA analysis reveals that hybridization between Fasciola hepatica and Fasciola gigantica occurred in China.

    Science.gov (United States)

    Ichikawa-Seki, Madoka; Peng, Mao; Hayashi, Kei; Shoriki, Takuya; Mohanta, Uday Kumar; Shibahara, Toshiyuki; Itagaki, Tadashi

    2017-02-01

    The well-known pathogens of fasciolosis, Fasciola hepatica (Fh) and Fasciola Gigantica (Fg), possess abundant mature sperms in their seminal vesicles, and thus, they reproduce bisexually. On the other hand, aspermic Fasciola flukes reported from Asian countries, which have no sperm in their seminal vesicles, probably reproduce parthenogenetically. The aim of this study was to reveal the origin of aspermic Fasciola flukes. The nuclear single copy markers, phosphoenolpyruvate carboxykinase and DNA polymerase delta, were employed for analysis of Fasciola species from China. The hybrid origin of aspermic Fasciola flukes was strongly suggested by the presence of the Fh/Fg type, which includes DNA fragments of both F. hepatica and F. gigantica. China can be regarded as the cradle of the interspecific hybridization because F. hepatica and F. gigantica were detected in the northern and southern parts of China, respectively, and hybrids flukes were distributed between the habitats of the two species. The Chinese origin was supported by the fact that a larger number of mitochondrial NADH dehydrogenase subunit 1 (nad1) haplotypes was detected in Chinese aspermic Fasciola populations than in aspermic populations from the neighbouring countries. Hereafter, 'aspermic' Fasciola flukes should be termed as 'hybrid' Fasciola flukes.

  15. Analysis of plastome and chondriome genome types in potato somatic hybrids from Solanum tuberosum × Solanum etuberosum.

    Science.gov (United States)

    Tiwari, Jagesh K; Chandel, Poonam; Singh, Bir Pal; Bhardwaj, Vinay

    2014-01-01

    Cytoplasm types of the potato somatic hybrids from Solanum tuberosum × Solanum etuberosum were analysed using chloroplast (cp) and mitochondrial (mt) organelle genomes-specific markers. Of the 29 markers (15 cpDNA and 14 mtDNA) amplified in the 26 genotypes, 5 cpDNA (H3, NTCP4, NTCP8, NTCP9, and ALC1/ALC3) and 13 mtDNA markers showed polymorphism. The cluster analysis based on the mtDNA markers detected higher diversity compared with the cpDNA markers. Presence of new mtDNA fragments of the markers, namely, T11-2, Nsm1, pumD, Nsm3, and Nsm4, were observed, while monomorphic loci revealed highly conserved genomic regions in the somatic hybrids. The study revealed that the somatic hybrids had diverse cytoplasm types consisting predominantly of T-, W-, and C-, with a few A- and S-type cp genomes; and α-, β-, and γ-type mt genomes. Somatic hybridization has unique potential to widen the cytoplasm types of the cultivated gene pools from wild species through introgression by breeding methods.

  16. Dynamic Modeling and Simulation of a Thermoelectric-Solar Hybrid Energy System Using an Inverse Dynamic Analysis Input Shaper

    Directory of Open Access Journals (Sweden)

    A. M. Yusop

    2014-01-01

    Full Text Available This study presents the behavioral model of thermal temperature and power generation of a thermoelectric-solar hybrid energy system exposed to dynamic transient sources. In the development of thermoelectric-solar hybrid energy system, studies have focused on the regulation of both systems separately. In practice, a separate control system affects hardware pricing. In this study, an inverse dynamic analysis shaping technique based on exponential function is applied to a solar array (SA to stabilize output voltage before this technique is combined with a thermoelectric module (TEM. This method can be used to estimate the maximum power point of the hybrid system by initially shaping the input voltage of SA. The behavior of the overall system can be estimated by controlling the behavior of SA, such that SA can follow the output voltage of TEM as the time constant of TEM is greater than that of SA. Moreover, by employing a continuous and differentiable function, the acquired output behavior of the hybrid system can be attained. Data showing the model is obtained from current experiments with predicted values of temperature, internal resistance, and current attributes of TEM. The simulation results show that the proposed input shaper can be used to trigger the output voltage of SA to follow the TEM behavior under transient conditions.

  17. Analysis of the stability for yield in maize (Zea mays hybrids in the central Ecuadorian Coastal Region

    Directory of Open Access Journals (Sweden)

    Daniel Vera Aviles

    2013-09-01

    Full Text Available The objective of this study was to determine the stability of commercial and experimental maize hybrids in the Central Ecuadorian Coastal Region. During a period from december 2010 to april 2011 uniform trials of yield in four locations with contrasting environments were evaluated. The genetic material was constituted by five experimental hybrids and three commercial. The experimental design used was completely randomized blocks design with four replications; the experimental plots were two rows with a length of 5.0 m separated to 0.90 meters. The combined analysis of variance proposed by Eberhart and Russel was statistical significance as well as for genotype and for interaction. The average yield showed that between experimental hybrids two, (SM45 x SSD08SV39 and (SM45 x SV15SV39, were highlighted with averages higher than 7.0 t ha-1 whilst AG-003 was the highlighted commercial hybrid with a yield of 7.48 t ha-1. The best yields and environmental indexes were registered in the locations of Quevedo and Vinces, the lowest environmental indexes were for Balzar and Ventanas. In relation to the tendency of response of the outstanding genotypes in the four evaluation environments, it was particularly observed that genotypes are desirable by virtue of the outstanding results in both favorable and unfavorable environments.

  18. Karyotype evolution in Tilapia: mitotic and meiotic chromosome analysis of Oreochromis karongae and O. niloticus x O. karongae hybrids.

    Science.gov (United States)

    Harvey, S C; Campos-Ramos, R; Kennedy, D D; Ezaz, M T; Bromage, N R; Griffin, D K; Penman, D J

    2002-06-01

    The karyotype of Oreochromis species is considered to be highly conserved, with a diploid chromosome complement of 2n = 44. Here we show, by analysis of mitotic and meiotic chromosomes, that the karyotype of O. karongae, one of the Lake Malawi 'chambo' species, is 2n = 38. This difference in chromosome number does not prevent the production of inter-specific hybrids between O. niloticus (2n = 44) and O. karongae (2n = 38). Analysis of the meiotic chromosomes of the O. niloticus x O. karongae hybrids indicates that three separate chromosome fusion events have occurred in O. karongae. Comparison of the O. karongae and O. niloticus karyotypes suggests that these consist of one Robertsonian fusion and two fusions of a more complex nature.

  19. Meiotic analysis of interspecific hybrids between Capsicum frutescens and Capsicum chinense

    National Research Council Canada - National Science Library

    Nádia Fernandes Moreira; Telma Nair Santana Pereira; Kellen Coutinho Martins

    2017-01-01

    The aim of this study was to observe the genetic relationship between C. frutescens (UENF 1636) and C. chinense (UENF 1785) based on the meiotic behavior, on the meiotic index, and on pollen viability of their F1 hybrids...

  20. ANALYSIS OF AUGMENTED THREE-FIELD MACRO-HYBRID MIXED FINITE ELEMENT SCHEMES

    Institute of Scientific and Technical Information of China (English)

    Gonzalo Alduncin

    2009-01-01

    On the basis of composition duality principles, augmented three-field macro-hybrid mixed variational problems and finite element schemes are analyzed. The compati-bility condition adopted here, for compositional dualization, is the coupling operator surjec-tivity, property that expresses in a general operator sense the Ladysenskaja-Babuska-Brezzi inf-sup condition. Variational macro-hybridization is performed under the assumption of decomposable primal and dual spaces relative to nonoverlapping domain decompositions. Then, through compositional dualization macro-hybrid mixed problems are obtained, with internal boundary dual traces as Lagrange multipliers. Also, "mass" preconditioned aug-mentation of three-field formulations are derived, stabilizing macro-hybrid mixed finite element schemes and rendering possible speed up of rates of convergence. Dual mixed incompressible Darcy flow problems illustrate the theory throughout the paper.

  1. Performance analysis of multi-pump Raman+EDFA hybrid amplifiers for WDM systems

    Science.gov (United States)

    Jardim Martini, Márcia M.; Pontes, Maria José; Ribeiro, Moisés. R. N.; Kalinowski, Hypolito José

    2014-08-01

    An approximated technique to optimize the gain profile of multi-pump broadband hybrid amplifiers (Raman+EDFA) under residual pump recycling is applied to a WDM system. The Optimized hybrid amplifier configurations with multi-pumping were analyzed considering different number of input channels in order to check the global gain saturation and the changes in the global gain profile that occur due to signal-pump, signal-signal, and pump-pump interactions. This work extends the optimization of the gain profile from Raman+EDFA hybrid amplifiers and studies the signal-signal interactions, signal-pumping and pumping-pumping WDM systems. Multiple input channels allowed the gain characterization of the Raman+EDFA hybrid amplifier in terms of global gain, ripple, and noise figure considering applications for WDM systems.

  2. Brake Performance Analysis of ABS for Eddy Current and Electrohydraulic Hybrid Brake System

    Directory of Open Access Journals (Sweden)

    Ren He

    2013-01-01

    Full Text Available This paper introduces an eddy current and electro-hydraulic hybrid brake system to solve problems such as wear, thermal failure, and slow response of traditional vehicle brake system. Mathematical model was built to calculate the torque of the eddy current brake system and hydraulic brake system and analyze the braking force distribution between two types of brake systems. A fuzzy controller on personal computer based on LabVIEW and Matlab was designed and a set of hardware in the loop system was constructed to validate and analyze the performance of the hybrid brake system. Through lots of experiments on dry and wet asphalt roads, the hybrid brake system achieves perfect performance on the experimental bench, the hybrid system reduces abrasion and temperature of the brake disk, response speed is enhanced obviously, fuzzy controller keeps high utilization coefficient due to the optimal slip ratio regulation, and the total brake time has a smaller decrease than traditional hydraulic brake system.

  3. Analysis of comparative genomic hybridization and loss of heterozygosity in 43 primary gastric carcinomas

    Institute of Scientific and Technical Information of China (English)

    王琦; 王柏秋; 关新元; 高慧; 程慧; 张岂凡; 黄承斌; 李璞; 傅松滨

    2003-01-01

    Objective To investigate common chromosomal changes and the LOH frequency of microsatellite loci in primary gastric cancer samples in order to locate the deleted regions in which human gastric cancer related genes might exist.Methods Comparative genomic hybridization (CGH) was used to define global chromosomal aberrations in 43 primary gastric tumors. Based on the results of CGH, analysis of loss of heterozygosity (LOH) was performed in chromosome 19 in which the loss was first discovered in the gastric cancers. The PCR-based approach was used to investigate 22 loci, which are spaced at 1.1-10.9 cM intervals throughout chromosome 19. The amplified PCR fragments were subjected to electrophoresis in PAGE gel and analyzed with GenescanTM and GenotyperTM. Results CGH analysis revealed gains in chromosome 3p(8/43), 8q(8/43), 20 [20 (9/43), 20p(7/43), 20q(4/43)], 12q(16/43), 13q(12/43) and losses in 19 [19 (15/43)], 7 [17 (8/43), 17p (10/43)], 16 (10/43) and 1p (11/43). Among the 43 evaluated samples, the most frequent LOH was detected at locus D19S571 (27.81%). Conclusions The tumorigenesis of gastric cancer includes several chromosomal changes. The aberration of chromosome 19 was the first common change founded in gastric cancer. The region near the D19S571 might harbor potential genes related to the tumorigenesis of gastric cancer.

  4. A hybrid least squares and principal component analysis algorithm for Raman spectroscopy.

    Directory of Open Access Journals (Sweden)

    Dominique Van de Sompel

    Full Text Available Raman spectroscopy is a powerful technique for detecting and quantifying analytes in chemical mixtures. A critical part of Raman spectroscopy is the use of a computer algorithm to analyze the measured Raman spectra. The most commonly used algorithm is the classical least squares method, which is popular due to its speed and ease of implementation. However, it is sensitive to inaccuracies or variations in the reference spectra of the analytes (compounds of interest and the background. Many algorithms, primarily multivariate calibration methods, have been proposed that increase robustness to such variations. In this study, we propose a novel method that improves robustness even further by explicitly modeling variations in both the background and analyte signals. More specifically, it extends the classical least squares model by allowing the declared reference spectra to vary in accordance with the principal components obtained from training sets of spectra measured in prior characterization experiments. The amount of variation allowed is constrained by the eigenvalues of this principal component analysis. We compare the novel algorithm to the least squares method with a low-order polynomial residual model, as well as a state-of-the-art hybrid linear analysis method. The latter is a multivariate calibration method designed specifically to improve robustness to background variability in cases where training spectra of the background, as well as the mean spectrum of the analyte, are available. We demonstrate the novel algorithm's superior performance by comparing quantitative error metrics generated by each method. The experiments consider both simulated data and experimental data acquired from in vitro solutions of Raman-enhanced gold-silica nanoparticles.

  5. A hybrid least squares and principal component analysis algorithm for Raman spectroscopy.

    Science.gov (United States)

    Van de Sompel, Dominique; Garai, Ellis; Zavaleta, Cristina; Gambhir, Sanjiv Sam

    2012-01-01

    Raman spectroscopy is a powerful technique for detecting and quantifying analytes in chemical mixtures. A critical part of Raman spectroscopy is the use of a computer algorithm to analyze the measured Raman spectra. The most commonly used algorithm is the classical least squares method, which is popular due to its speed and ease of implementation. However, it is sensitive to inaccuracies or variations in the reference spectra of the analytes (compounds of interest) and the background. Many algorithms, primarily multivariate calibration methods, have been proposed that increase robustness to such variations. In this study, we propose a novel method that improves robustness even further by explicitly modeling variations in both the background and analyte signals. More specifically, it extends the classical least squares model by allowing the declared reference spectra to vary in accordance with the principal components obtained from training sets of spectra measured in prior characterization experiments. The amount of variation allowed is constrained by the eigenvalues of this principal component analysis. We compare the novel algorithm to the least squares method with a low-order polynomial residual model, as well as a state-of-the-art hybrid linear analysis method. The latter is a multivariate calibration method designed specifically to improve robustness to background variability in cases where training spectra of the background, as well as the mean spectrum of the analyte, are available. We demonstrate the novel algorithm's superior performance by comparing quantitative error metrics generated by each method. The experiments consider both simulated data and experimental data acquired from in vitro solutions of Raman-enhanced gold-silica nanoparticles.

  6. Design, Construction and Effectiveness Analysis of Hybrid Automatic Solar Tracking System for Amorphous and Crystalline Solar Cells

    OpenAIRE

    Bhupendra Gupta

    2013-01-01

    - This paper concerns the design and construction of a Hybrid solar tracking system. The constructed device was implemented by integrating it with Amorphous & Crystalline Solar Panel, three dimensional freedom mechanism and microcontroller. The amount of power available from a photovoltaic panel is determined by three parameters, the type of solar tracker, materials of solar panel and the intensity of the sunlight. The objective of this paper is to present analysis on the use of two differ...

  7. Ecophysiological Analysis of Microorganisms in Complex Microbial Systems by Combination of Fluorescence In Situ Hybridization with Extracellular Staining Techniques

    Science.gov (United States)

    Nielsen, Jeppe Lund; Kragelund, Caroline; Nielsen, Per Halkjær

    Ecophysiological analysis and functions of single cells in complex microbial systems can be examined by simple combinations of Fluorescence in situ hybridization (FISH) for identification with various staining techniques targeting functional phenotypes. In this chapter, we describe methods and protocols optimized for the study of extracellular enzymes, surface hydrophobicity and specific surface structures. Although primarily applied to the study of microbes in wastewater treatment (activated sludge and biofilms), the methods may also be used with minor modifications in several other ecosystems.

  8. Near-term hybrid vehicle program, phase 1. Appendix A: Mission analysis and performance specification studies report

    Science.gov (United States)

    1979-01-01

    Results of a study leading to the preliminary design of a five passenger hybrid vehicle utilizing two energy sources (electricity and gasoline/diesel fuel) to minimize petroleum usage on a fleet basis are presented. The study methodology is described. Vehicle characterizations, the mission description, characterization, and impact on potential sales, and the rationale for the selection of the reference internal combustion engine vehicle are presented. Conclusions and recommendations of the mission analysis and performance specification report are included.

  9. Analysis of the inner collection efficiency in hybrid silicon solar cells

    OpenAIRE

    Nubile, P.; Torres, P; Hof, Ch.; Fischer, D.

    2008-01-01

    The collection of photogenerated carriers in hybrid silicon solar cells structures were determined by the DICE (dynamic inner collection efficiency) technique. The hybrid solar cells have a microcrystalline n-type emitter and a crystalline p-type base. Cells with amorphous buffers of several thickness and p+ back surface field microcrystalline layers were also studied. Spectral response and reflectivity were measured for each sample in order to obtain the internal spectral response or quantum...

  10. Electromagnetic Analysis and Design of Switched Reluctance Double-Rotor Machine for Hybrid Electric Vehicles

    OpenAIRE

    Shouliang Han; Shumei Cui; Liwei Song; Ching Chuen Chan

    2014-01-01

    The double-rotor machine is a kind of multiple input and output electromechanical energy transducer with two electrical ports and two mechanical ports, which is an ideal transmission system for hybrid electric vehicles and has a series of advantages such as integration of power and energy, high efficiency and compaction. In this paper, a switched reluctance double-rotor machine (SRDRM) is proposed for hybrid electric vehicles, while no conductor or PM in the middle rotor. This machine not onl...

  11. Insight into octoploid strawberry (Fragaria) subgenome composition revealed by GISH analysis of pentaploid hybrids.

    Science.gov (United States)

    Liu, Bo; Poulsen, Elizabeth G; Davis, Thomas M

    2016-02-01

    As the product of interspecific hybridization between its two ancestral octoploid (2n = 8x = 56) species (Fragaria chiloensis and F. virginiana), the cultivated strawberry (F. ×ananassa) is among the most genomically complex of crop plants, harboring subgenomic components derived from as many as four different diploid ancestors. To physically visualize the octoploids' subgenome composition(s), we launched molecular cytogenetic studies using genomic in situ hybridization (GISH), comparative GISH (cGISH), and rDNA-FISH techniques. First, GISH resolution in Fragaria was tested by using diploid and triploid hybrids with predetermined genome compositions. Then, observation of an octoploid genome was implemented by hybridizing chromosomes of pentaploid (2n = 5x = 35) hybrids from F. vesca × F. virginiana with genomic DNA probes derived from diploids (2n = 2x = 14) F. vesca and F. iinumae, which have been proposed by phylogenetic studies to be closely related to the octoploids yet highly divergent from each other. GISH and cGISH results indicated that octoploid-derived gametes (n = 4x = 28) carried seven chromosomes with hybridization affinities to F. vesca, while the remaining 21 chromosomes displayed varying affinities to F. iinumae, indicating differing degrees of subgenomic contribution to the octoploids by these two putatively ancestral diploids. Combined rDNA-FISH revealed severe 25S rDNA loss in both the F. vesca- and F. iinumae-like chromosome groups, while only the prior group retained its 5S loci.

  12. Near-term hybrid vehicle program, phase 1. Appendix D: Sensitivity analysis resport

    Science.gov (United States)

    1979-01-01

    Parametric analyses, using a hybrid vehicle synthesis and economics program (HYVELD) are described investigating the sensitivity of hybrid vehicle cost, fuel usage, utility, and marketability to changes in travel statistics, energy costs, vehicle lifetime and maintenance, owner use patterns, internal combustion engine (ICE) reference vehicle fuel economy, and drive-line component costs and type. The lowest initial cost of the hybrid vehicle would be $1200 to $1500 higher than that of the conventional vehicle. For nominal energy costs ($1.00/gal for gasoline and 4.2 cents/kWh for electricity), the ownership cost of the hybrid vehicle is projected to be 0.5 to 1.0 cents/mi less than the conventional ICE vehicle. To attain this ownership cost differential, the lifetime of the hybrid vehicle must be extended to 12 years and its maintenance cost reduced by 25 percent compared with the conventional vehicle. The ownership cost advantage of the hybrid vehicle increases rapidly as the price of fuel increases from $1 to $2/gal.

  13. Investigation of Genetic Distance among Parental Lines of Hybrid Rice Based on Cluster Analysis of Morphological Traits

    Directory of Open Access Journals (Sweden)

    A. Baluch-Zehi

    2013-06-01

    Full Text Available conditions. Thus, these varieties could be suitable option for yield increase and an effective step toward food security. Selection of parental lines has essential role in developing ideal combinations. Therefore, it is essential to study the relationship and genetic diversity among parental lines in hybrid rice. Sixteen hybrid rice parental lines including 6 restorer lines (Poya, Sepidrud, Pajohesh, R2, R9 and IR50 and 5 CMS lines (Neda, Nemat, Dasht, Champa and Amol 3 with their 5 maintainers were studied at Research Farm of Sari Agricultural Sciences and Natural Resources University during 2011. Analysis of variance showed significant variations for all of the studied traits, which shows great diversity among the genotypes. The number of fertile tillers and length to width ratio of grain showed positive and significant correlation with yield. But, grain width showed negative and significant correlation with yield. Results of principal component analysis revealed that 3 components explained 75.64% of the total variations. Cluster analysis at 15 genetic distance criteria grouped genotypes in 4 clusters. In exploration of heterosis phenomenon, parents must be far away from each other. So, the results of this study suggested crosses between CMS lines of Neda A, Nemat A and Champa A with each of restorer lines R9, R2, IR50 and Poya for experimental hybrid seed production.

  14. Techno-economical Analysis of Hybrid PV-WT-Hydrogen FC System for a Residential Building with Low Power Consumption

    Directory of Open Access Journals (Sweden)

    Badea G.

    2016-12-01

    Full Text Available This paper shows a techno-economical analysis on performance indicators of hybrid solar-wind-hydrogen power generation system which supply with electricity a low - energy building, located in Cluj-Napoca. The case study had the main objectives, as follows: cost estimation, evaluation of energy and environmental performance for a fuel cell integrated into a small-scale hybrid system power generation and estimation of electrolytic hydrogen production based on renewable energy resources available on the proposed site. The results presented in this paper illustrate a case study for location Cluj-Napoca. The wind and solar resource can play an important role in energy needs for periods with "peak load" or intermittent energy supply. However, hydrogen production is dependent directly proportional to the availability of renewable energy resources, but the hydrogen can be considered as a storage medium for these renewable resources. It can be said that this study is a small-scale model analysis, a starting point for a detailed analysis of Romania's potential electrolytic production of hydrogen from renewable resources and supply electricity using fuel cells integrated into hybrid energy systems.

  15. Fatigue and Damage Tolerance Analysis of a Hybrid Composite Tapered Flexbeam

    Science.gov (United States)

    Murri, Gretchen B.; Schaff, Jeffrey R.; Dobyns, Al

    2001-01-01

    The behavior of nonlinear tapered composite flexbeams under combined axial tension and cyclic bending loading was studied using coupon test specimens and finite element (FE) analyses. The flexbeams used a hybrid material system of graphite/epoxy and glass/epoxy and had internal dropped plies, dropped in an overlapping stepwise pattern. Two material configurations, differing only in the use of glass or graphite plies in the continuous plies near the midplane, were studied. Test specimens were cut from a full-size helicopter tail-rotor flexbeam and were tested in a hydraulic load frame under combined constant axialtension load and transverse cyclic bending loads. The first determination damage observed in the specimens occurred at the area around the tip of the outermost ply-drop group in the tapered region of the flexbeam, near the thick end. Delaminations grew slowly and stably, toward the thick end of the flexbeam, at the interfaces above and below the dropped-ply region. A 2D finite element model of the flexbeam was developed. The model was analyzed using a geometrically non-linear analysis with both the ANSYS and ABAQUS FE codes. The global responses of each analysis agreed well with the test results. The ANSYS model was used to calculate strain energy release rates (G) for delaminations initiating at two different ply-ending locations. The results showed that delaminations were more inclined to grow at the locations where they were observed in the test specimens. Both ANSYS and ABAQUS were used to calculate G values associated with delamination initiating at the observed location but growing in different interfaces, either above or below the ply-ending group toward the thick end, or toward the thin end from the tip of the resin pocket. The different analysis codes generated the same trends and comparable peak values, within 5-11 % for each delamination path. Both codes showed that delamination toward the thick region was largely mode II, and toward the thin

  16. Modeling and performance analysis of a closed-loop supply chain using first-order hybrid Petri nets

    Directory of Open Access Journals (Sweden)

    Imane Outmal

    2016-05-01

    Full Text Available Green or closed-loop supply chain had been the focus of many manufacturers during the last decade. The application of closed-loop supply chain in today’s manufacturing is not only due to growing environmental concerns and the recognition of its benefits in reducing greenhouse gas emissions, energy consumption, and meeting a more strict environmental regulations but it also offers economic competitive advantages if appropriately managed. First-order hybrid Petri nets represent a powerful graphical and mathematical formalism to map and analyze the dynamics of complex systems such as closed-loop supply chain networks. This article aims at illustrating the use of first-order hybrid Petri nets to model a closed-loop supply chain network and evaluate its operational, financial, and environmental performance measures under different management policies. Actual data from auto manufacturer in the United States are used to validate network’s performance under both tactical and strategic decision-making, namely, (1 tactical decision—production policies: increase of recovered versus new components and (2 strategic decision—closed-loop supply chain network structure: manufacturer internal recovery process or recovery process done by a third-party collection and recovery center. The work presented in this article is an extension of the use of first-order hybrid Petri nets as a modeling and performance analysis tool from supply chain to closed-loop supply chain. The modularity property of first-order hybrid Petri nets has been used in the modeling process, and the simulation and analysis of the modeled network are done in MATLAB® environment. The results of the experiments depict that first-order hybrid Petri nets are a powerful modeling and analysis formalism for closed-loop supply chain networks and can be further used as an efficient decision-making tool at both tactical and strategic levels. Unlike other researches on modeling supply chain

  17. Feasibility study and techno-economic analysis of an SOFC/battery hybrid system for vehicle applications

    Science.gov (United States)

    Aguiar, P.; Brett, D. J. L.; Brandon, N. P.

    A feasibility study and techno-economic analysis for a hybrid power system intended for vehicular traction applications has been performed. The hybrid consists of an intermediate temperature solid oxide fuel cell (IT-SOFC) operating at 500-800 °C and a sodium-nickel chloride (ZEBRA) battery operating at 300 °C. Such a hybrid system has the benefits of extended range and fuel flexibility (due to the IT-SOFC), high power output and rapid response time (due to the battery). The above hybrid has been compared to a fuel cell-only, a battery-only and an ICE vehicle. It is shown that the capital cost associated with a fuel cell-only vehicle is still much higher than that of any other power source option and that a battery-only option would potentially encounter weight and volume limitations, particularly for long drive times. It is concluded that increasing drive time per day decreases substantially the payback time in relation to an ICE vehicle running on gasoline and thus that the hybrid vehicle is an economically attractive option for commercial vehicles with long drive times. In the case where the battery has reached volume production prices at £70 kWh -1 and current fuel duty values remain unchanged then a payback time gasoline equivalent fuel economy of 25.1 km L -1, almost twice that of a gasoline fuelled ICE vehicle of the same size, and CO 2 emissions of 71.6 g km -1, well below any new technology target set so far. It is therefore recommended that a SOFC/ZEBRA demonstration be built to further explore its viability.

  18. Genetic analysis of an ephemeral intraspecific hybrid zone in the hypervariable tree, Metrosideros polymorpha, on Hawai'i Island.

    Science.gov (United States)

    Stacy, E A; Johansen, J B; Sakishima, T; Price, D K

    2016-09-01

    Intraspecific hybrid zones involving long-lived woody species are rare and can provide insights into the genetic basis of early-diverging traits in speciation. Within the landscape-dominant Hawaiian tree, Metrosideros polymorpha, are morphologically distinct successional varieties, incana and glaberrima, that dominate new and old lava flows, respectively, below 1200 me on volcanically active Hawai'i Island, with var. glaberrima also extending to higher elevations and bogs. Here, we use morphological measurements on 86 adult trees to document the presence of an incana-glaberrima hybrid zone on the 1855 Mauna Loa lava flow on east Hawai'i Island and parent-offspring analysis of 1311 greenhouse seedlings from 71 crosses involving 72 adults to estimate heritabilities and genetic correlations among vegetative traits. Both the variation in adult leaf pubescence at the site and the consistency between adult and offspring phenotypes suggest the presence of two hybrid classes, F1s and var. incana backcrosses, as would be expected on a relatively young lava flow. Nine nuclear microsatellite loci failed to distinguish parental and hybrid genotypes. All four leaf traits examined showed an additive genetic basis with moderate to strong heritabilities, and genetic correlations were stronger for the more range-restricted var. incana. The differences between varieties in trait values, heritabilities and genetic correlations, coupled with high genetic variation within but low genetic variation between varieties, are consistent with a multi-million-year history of alternating periods of disruptive selection in contrasting environments and admixture in ephemeral hybrid zones. Finally, the contrasting genetic architectures suggest different evolutionary trajectories of leaf traits in these forms.

  19. Analysis of Upper Hybrid Wave Growth Rates From Measured Electron Distributions; An Encounter With the Source of Auroral Roar

    Science.gov (United States)

    Bounds, S. R.; Kletzing, C. A.; Labelle, J. W.; Samara, M.; Yoon, P. H.

    2005-12-01

    In January of 2003, the High Bandwidth Auroral Rocket (HIBAR) passed through two regions of strong upper hybrid wave emission associated with the approximate matching of the upper hybrid frequency to twice the electron cyclotron frequency (fuh = 2 fce) (Samara 2004) These types of emission are believed to be the source of the HF auroral roar often observed by ground based receivers. The current model theorizes that the free space 0-mode waves observed on the ground are produced through mode conversion of strong emission of Z-mode, or upper hybrid waves. The relativistic electron cyclotron maser exhibits significant growth rates for the Z-mode when the local upper hybrid frequency is just below (~1%) twice the electron cyclotron frequency and with the appropriately unstable electron distribution (Yoon 1996, Yoon 1998, Yoon 2000). Though auroral roar is frequently observed from the ground, the source region has rarely been identified in-situ and even more rarely with sufficient bandwidth to analyze the underlying physical processes. Analysis of the electron distributions from HIBAR show good agreement with the theoretical distributions used by Yoon:98. HIBAR encountered three separate regions where fuh ≍ 2 fce, two of these regions include strong upper hybrid emission, while the third is void of upper hybrid wave activity. The measured particle distributions demonstrate that, in the two regions with wave emission, the relativistic electron cyclotron maser instability produces Z mode wave growth rates at least an order of magnitude greater than the electron collision frequency. In the third region without wave emission, the growth rates are much smaller in both amplitude and the extent of occurance. Samara, M., J. LaBelle, C. A. Kletzing, and S. R. Bounds, Rocket observations of structured upper hybrid wave at fuh=2fce, Geophys. Res. Lett., 31, L22804, doi:10.1029/2004GL021043. Yoon, P. H., A. T. Weatherwax, and T. J. Rosenberg, Lower ionospheric cyclotron maser

  20. Hybrid metabolic flux analysis: combining stoichiometric and statistical constraints to model the formation of complex recombinant products

    Directory of Open Access Journals (Sweden)

    Alves Paula M

    2011-02-01

    Full Text Available Abstract Background Stoichiometric models constitute the basic framework for fluxome quantification in the realm of metabolic engineering. A recurrent bottleneck, however, is the establishment of consistent stoichiometric models for the synthesis of recombinant proteins or viruses. Although optimization algorithms for in silico metabolic redesign have been developed in the context of genome-scale stoichiometric models for small molecule production, still rudimentary knowledge of how different cellular levels are regulated and phenotypically expressed prevents their full applicability for complex product optimization. Results A hybrid framework is presented combining classical metabolic flux analysis with projection to latent structures to further link estimated metabolic fluxes with measured productivities. We first explore the functional metabolic decomposition of a baculovirus-producing insect cell line from experimental data, highlighting the TCA cycle and mitochondrial respiration as pathways strongly associated with viral replication. To reduce uncertainty in metabolic target identification, a Monte Carlo sampling method was used to select meaningful associations with the target, from which 66% of the estimated fluxome had to be screened out due to weak correlations and/or high estimation errors. The proposed hybrid model was then validated using a subset of preliminary experiments to pinpoint the same determinant pathways, while predicting the productivity of independent cultures. Conclusions Overall, the results indicate our hybrid metabolic flux analysis framework is an advantageous tool for metabolic identification and quantification in incomplete or ill-defined metabolic networks. As experimental and computational solutions for constructing comprehensive global cellular models are in development, the contribution of hybrid metabolic flux analysis should constitute a valuable complement to current computational platforms in bridging the

  1. Fine Mapping and Transcriptome Analysis Reveal Candidate Genes Associated with Hybrid Lethality in Cabbage (Brassica Oleracea).

    Science.gov (United States)

    Xiao, Zhiliang; Hu, Yang; Zhang, Xiaoli; Xue, Yuqian; Fang, Zhiyuan; Yang, Limei; Zhang, Yangyong; Liu, Yumei; Li, Zhansheng; Liu, Xing; Liu, Zezhou; Lv, Honghao; Zhuang, Mu

    2017-06-05

    Hybrid lethality is a deleterious phenotype that is vital to species evolution. We previously reported hybrid lethality in cabbage (Brassica oleracea) and performed preliminary mapping of related genes. In the present study, the fine mapping of hybrid lethal genes revealed that BoHL1 was located on chromosome C1 between BoHLTO124 and BoHLTO130, with an interval of 101 kb. BoHL2 was confirmed to be between insertion-deletion (InDels) markers HL234 and HL235 on C4, with a marker interval of 70 kb. Twenty-eight and nine annotated genes were found within the two intervals of BoHL1 and BoHL2, respectively. We also applied RNA-Seq to analyze hybrid lethality in cabbage. In the region of BoHL1, seven differentially expressed genes (DEGs) and five resistance (R)-related genes (two in common, i.e., Bo1g153320 and Bo1g153380) were found, whereas in the region of BoHL2, two DEGs and four R-related genes (two in common, i.e., Bo4g173780 and Bo4g173810) were found. Along with studies in which R genes were frequently involved in hybrid lethality in other plants, these interesting R-DEGs may be good candidates associated with hybrid lethality. We also used SNP/InDel analyses and quantitative real-time PCR to confirm the results. This work provides new insight into the mechanisms of hybrid lethality in cabbage.

  2. Thermodynamic exergy analysis for small modular reactor in nuclear hybrid energy system

    Directory of Open Access Journals (Sweden)

    Boldon Lauren

    2016-01-01

    Full Text Available Small modular reactors (SMRs provide a unique opportunity for future nuclear development with reduced financial risks, allowing the United States to meet growing energy demands through safe, reliable, clean air electricity generation while reducing greenhouse gas emissions and the reliance on unstable fossil fuel prices. A nuclear power plant is comprised of several complex subsystems which utilize materials from other subsystems and their surroundings. The economic utility of resources, or thermoeconomics, is extremely difficult to analyze, particularly when trying to optimize resources and costs among individual subsystems and determine prices for products. Economics and thermodynamics cannot provide this information individually. Thermoeconomics, however, provides a method of coupling the quality of energy available based on exergy and the value of this available energy – “exergetic costs”. For an SMR exergy analysis, both the physical and economic environments must be considered. The physical environment incorporates the energy, raw materials, and reference environment, where the reference environment refers to natural resources available without limit and without cost, such as air input to a boiler. The economic environment includes market influences and prices in addition to installation, operation, and maintenance costs required for production to occur. The exergetic cost or the required exergy for production may be determined by analyzing the physical environment alone. However, to optimize the system economics, this environment must be coupled with the economic environment. A balance exists between enhancing systems to improve efficiency and optimizing costs. Prior research into SMR thermodynamics has not detailed methods on improving exergetic costs for an SMR coupled with storage technologies and renewable energy such as wind or solar in a hybrid energy system. This process requires balancing technological efficiencies and

  3. Characteristics and thermal behavior analysis of lithium-ion batteries for application in hybrid locomotives

    Science.gov (United States)

    Chatterjee, Krishnashis

    The locomotive industry accounts for 2.5 % of the total fuel consumption in the US. Thus the necessity for reducing fuel consumption and emissions led to the development of the concept of hybrid locomotive which is dual powered by the diesel engine and electric motors. But the energy dissipated in braking such a locomotive in a year is enough to power over 9100 average US households over the same period of time. Recovering this energy using regenerative braking system and storing it in a electric battery is of great interest among researchers for improving overall efficiency and reducing consumption of fuels. In the present study, LiFePO4 batteries, a type of the state-of-art lithium-ion batteries, have been tested under different environmental and load conditions. Environmental temperatures were varied to analyze their effects on the charging and discharging patterns of the battery by using the CADEX battery analyzer in order to find the temperature range for optimum battery performance. The fluctuations of temperature of the battery surface were monitored along the length of the tests, using Infra-Red imaging and thermocouple probes at different points on the battery surface. Both battery performance characteristics and the variation of the battery surface temperature were also recorded for different load cycles in order to get a comprehensive picture of the heat generation and its effect on the behavior of the battery under different load conditions. Lastly a practical Load Cycle analysis of the battery has been performed which gave a picture of the heat generated by the battery and also the performance characteristics as it is subjected to a practical Load Cycle.

  4. Numeric Design and Performance Analysis of Solid Oxide Fuel Cell -- Gas Turbine Hybrids on Aircraft

    Science.gov (United States)

    Hovakimyan, Gevorg

    The aircraft industry benefits greatly from small improvements in aircraft component design. One possible area of improvement is in the Auxiliary Power Unit (APU). Modern aircraft APUs are gas turbines located in the tail section of the aircraft that generate additional power when needed. Unfortunately the efficiency of modern aircraft APUs is low. Solid Oxide Fuel Cell/Gas Turbine (SOFC/GT) hybrids are one possible alternative for replacing modern gas turbine APUs. This thesis investigates the feasibility of replacing conventional gas turbine APUs with SOFC/GT APUs on aircraft. An SOFC/GT design algorithm was created in order to determine the specifications of an SOFC/GT APU. The design algorithm is comprised of several integrated modules which together model the characteristics of each component of the SOFC/GT system. Given certain overall inputs, through numerical analysis, the algorithm produces an SOFC/GT APU, optimized for specific power and efficiency, capable of performing to the required specifications. The SOFC/GT design is then input into a previously developed quasi-dynamic SOFC/GT model to determine its load following capabilities over an aircraft flight cycle. Finally an aircraft range study is conducted to determine the feasibility of the SOFC/GT APU as a replacement for the conventional gas turbine APU. The design results show that SOFC/GT APUs have lower specific power than GT systems, but have much higher efficiencies. Moreover, the dynamic simulation results show that SOFC/GT APUs are capable of following modern flight loads. Finally, the range study determined that SOFC/GT APUs are more attractive over conventional APUs for longer range aircraft.

  5. Hybrid System Modeling and Full Cycle Operation Analysis of a Two-Stroke Free-Piston Linear Generator

    Directory of Open Access Journals (Sweden)

    Peng Sun

    2017-02-01

    Full Text Available Free-piston linear generators (FPLGs have attractive application prospects for hybrid electric vehicles (HEVs owing to their high-efficiency, low-emissions and multi-fuel flexibility. In order to achieve long-term stable operation, the hybrid system design and full-cycle operation strategy are essential factors that should be considered. A 25 kW FPLG consisting of an internal combustion engine (ICE, a linear electric machine (LEM and a gas spring (GS is designed. To improve the power density and generating efficiency, the LEM is assembled with two modular flat-type double-sided PM LEM units, which sandwich a common moving-magnet plate supported by a middle keel beam and bilateral slide guide rails to enhance the stiffness of the moving plate. For the convenience of operation processes analysis, the coupling hybrid system is modeled mathematically and a full cycle simulation model is established. Top-level systemic control strategies including the starting, stable operating, fault recovering and stopping strategies are analyzed and discussed. The analysis results validate that the system can run stably and robustly with the proposed full cycle operation strategy. The effective electric output power can reach 26.36 kW with an overall system efficiency of 36.32%.

  6. Control Strategies, Robustness Analysis, Digital Simulation and Practical Implementation for a Hybrid APF with a Resonant Ac-link

    Directory of Open Access Journals (Sweden)

    Chen Chen

    2010-12-01

    Full Text Available This paper proposes a novel hybrid active power filter (HAPF topology based onthe cascaded connection of the AC-side capacitor and the third-order LCL-filter, which hasthe advantage of the conventional hybrid filter and the LCL-filter in terms of reduced dclinkvoltage and better switching ripple attenuation. The robust deadbeat control law isderived for the current loop, with special emphasis on robustness analysis. The stabilityand robustness analysis under parameter variations are presented for the converter-sidecurrent tracking scheme and the grid-side current tracking scheme. It is found that thestability margins obtained from the converter-side current tracking control scheme aregenerally higher than those obtained from the grid-side current tracking scheme. However,the converter-side current tracking scheme is sensitive to the variation of the dampingresistance, and it would impose additional parameter uncertainty on the control system andcomplicate the problem. Hence the grid-side current tracking scheme is implemented. Thesimulation results obtained from Matlab/Simulink are presented for verification, where theinductance variation and grid disturbance scenarios are also taken into consideration. Theeffectiveness of the proposed hybrid APF is substantially confirmed by the simulation andexperimental results.

  7. Pre-design and life cycle cost analysis of a hybrid power system for rural and remote communities in Afghanistan

    Directory of Open Access Journals (Sweden)

    Mir Sayed Shah Danish

    2014-08-01

    Full Text Available In view of the present situation of the Afghanistan electricity sector, the photovoltaic and diesel generator stand-alone hybrid power system is increasingly attractive for application in rural and remote communities. Thousands of rural communities in Afghanistan depend solely on traditional kerosene for illumination and rarely have access to electricity sources such as DC battery for radio and other small appliances. This study is conducted to offer real-life solution to this problem. The hybrid system is investigated to meet the domestic load demand that is estimated based on the communities’ electricity consumption culture. At first, customary pre-design is pursued. Afterwards, the break-even point and net present value algorithms are applied for economic analysis. That makes this study differ from the previous academic literature. The concepts developed in this study are targeted for a cost-effective hybrid system, which is appropriate for rural and remote residents’ lifestyle change and improvement. Based on the academic research methods, overall analysis procedures can fit as an analogy, especially for developing countries.

  8. Techno-economic analysis of hybrid power system sizing applied to small desalination plants for sustainable operation

    Directory of Open Access Journals (Sweden)

    R. Nagaraj

    2016-12-01

    Full Text Available Water and energy are two inseparable commodities that govern the lives of humanity and promote civilization. Energy can be used to produce water in case of scarcity in water. Ironically most of the places that are water stressed are also energy stressed. The cost of extending grid power may be prohibitively high in those cases. Rural/remote locations like hills and islands multiply the problem to a larger magnitude. Use of renewable sources like solar, wind, biomass and other locally available energy sources is the only solution. But these renewable sources are of intermittent nature and have poor availability. Hence, it is practically difficult to produce water with a single source of energy. Naturally, combining two or more sources of energy, known as hybrid power system, is the next available option. This paper carries out a techno-economic analysis of various sizing combinations of systems with solar photo voltaic, wind energy and stored energy in batteries for production of drinking water from a brackish water source. The system can operate the RO plant whenever the power is available, produce drinking water and store in a tank. This paper analyses the model of the entire hybrid power system in MATLAB to simulate the performance of the hybrid power system for different combinations of capacities. Results of the analysis under various input conditions are analyzed.

  9. Novel hybrid GPU-CPU implementation of parallelized Monte Carlo parametric expectation maximization estimation method for population pharmacokinetic data analysis.

    Science.gov (United States)

    Ng, C M

    2013-10-01

    The development of a population PK/PD model, an essential component for model-based drug development, is both time- and labor-intensive. A graphical-processing unit (GPU) computing technology has been proposed and used to accelerate many scientific computations. The objective of this study was to develop a hybrid GPU-CPU implementation of parallelized Monte Carlo parametric expectation maximization (MCPEM) estimation algorithm for population PK data analysis. A hybrid GPU-CPU implementation of the MCPEM algorithm (MCPEMGPU) and identical algorithm that is designed for the single CPU (MCPEMCPU) were developed using MATLAB in a single computer equipped with dual Xeon 6-Core E5690 CPU and a NVIDIA Tesla C2070 GPU parallel computing card that contained 448 stream processors. Two different PK models with rich/sparse sampling design schemes were used to simulate population data in assessing the performance of MCPEMCPU and MCPEMGPU. Results were analyzed by comparing the parameter estimation and model computation times. Speedup factor was used to assess the relative benefit of parallelized MCPEMGPU over MCPEMCPU in shortening model computation time. The MCPEMGPU consistently achieved shorter computation time than the MCPEMCPU and can offer more than 48-fold speedup using a single GPU card. The novel hybrid GPU-CPU implementation of parallelized MCPEM algorithm developed in this study holds a great promise in serving as the core for the next-generation of modeling software for population PK/PD analysis.

  10. Biosynthesis-Based Quantitative Analysis of 151 Secondary Metabolites of Licorice To Differentiate Medicinal Glycyrrhiza Species and Their Hybrids.

    Science.gov (United States)

    Song, Wei; Qiao, Xue; Chen, Kuan; Wang, Ying; Ji, Shuai; Feng, Jin; Li, Kai; Lin, Yan; Ye, Min

    2017-03-07

    Secondary metabolites are usually the bioactive components of medicinal plants. The difference in the secondary metabolisms of closely related plant species and their hybrids has rarely been addressed. In this study, we conducted a holistic secondary metabolomics analysis of three medicinal Glycyrrhiza species (G. uralensis, G. glabra, and G. inflata), which are used as the popular herbal medicine licorice. The Glycyrrhiza species (genotype) for 95 batches of samples were identified by DNA barcodes of the internal transcribed spacer and trnV-ndhC regions, and the chemotypes were revealed by LC/UV- or LC/MS/MS-based quantitative analysis of 151 bioactive secondary metabolites, including 17 flavonoid glycosides, 24 saponins, and 110 free phenolic compounds. These compounds represented key products in the biosynthetic pathways of licorice. For the 76 homozygous samples, the three Glycyrrhiza species showed significant biosynthetic preferences, especially in coumarins, chalcones, isoflavanes, and flavonols. In total, 27 species-specific chemical markers were discovered. The 19 hybrid samples indicated that hybridization could remarkably alter the chemical composition and that the male parent contributed more to the offspring than the female parent did. This is hitherto the largest-scale targeted secondary metabolomics study of medicinal plants and the first report on uniparental inheritance in plant secondary metabolism. The results are valuable for biosynthesis, inheritance, and quality control studies of licorice and other medicinal plants.

  11. Marine Fish Hybridization

    KAUST Repository

    He, Song

    2017-04-01

    Natural hybridization is reproduction (without artificial influence) between two or more species/populations which are distinguishable from each other by heritable characters. Natural hybridizations among marine fishes were highly underappreciated due to limited research effort; it seems that this phenomenon occurs more often than is commonly recognized. As hybridization plays an important role in biodiversity processes in the marine environment, detecting hybridization events and investigating hybridization is important to understand and protect biodiversity. The first chapter sets the framework for this disseration study. The Cohesion Species Concept was selected as the working definition of a species for this study as it can handle marine fish hybridization events. The concept does not require restrictive species boundaries. A general history and background of natural hybridization in marine fishes is reviewed during in chapter as well. Four marine fish hybridization cases were examed and documented in Chapters 2 to 5. In each case study, at least one diagnostic nuclear marker, screened from among ~14 candidate markers, was found to discriminate the putative hybridizing parent species. To further investigate genetic evidence to support the hybrid status for each hybrid offspring in each case, haploweb analysis on diagnostic markers (nuclear and/or mitochondrial) and the DAPC/PCA analysis on microsatellite data were used. By combining the genetic evidences, morphological traits, and ecological observations together, the potential reasons that triggered each hybridization events and the potential genetic/ecology effects could be discussed. In the last chapter, sequences from 82 pairs of hybridizing parents species (for which COI barcoding sequences were available either on GenBank or in our lab) were collected. By comparing the COI fragment p-distance between each hybridizing parent species, some general questions about marine fish hybridization were discussed: Is

  12. Interspecies comparative genome hybridization and interspecies representational difference analysis reveal gross DNA differences between humans and great apes.

    Science.gov (United States)

    Toder, R; Xia, Y; Bausch, E

    1998-09-01

    Comparative chromosome G-/R-banding, comparative gene mapping and chromosome painting techniques have demonstrated that only few chromosomal rearrangements occurred during great ape and human evolution. Interspecies comparative genome hybridization (CGH), used here in this study, between human, gorilla and pygmy chimpanzee revealed species-specific regions in all three species. In contrast to the human, a far more complex distribution of species-specific blocks was detected with CGH in gorilla and pygmy chimpanzee. Most of these blocks coincide with already described heterochromatic regions on gorilla and chimpanzee chromosomes. Representational difference analysis (RDA) was used to subtract the complex genome of gorilla against human in order to enrich gorilla-specific DNA sequences. Gorilla-specific clones isolated with this technique revealed a 32-bp repeat unit. These clones were mapped by fluorescence in situ hybridization (FISH) to the telomeric regions of gorilla chromosomes that had been shown by interspecies CGH to contain species-specific sequences.

  13. Association between chromosomal aberration of COX8C and tethered spinal cord syndrome: array-based comparative genomic hybridization analysis

    Directory of Open Access Journals (Sweden)

    Qiu-jiong Zhao

    2016-01-01

    Full Text Available Copy number variations have been found in patients with neural tube abnormalities. In this study, we performed genome-wide screening using high-resolution array-based comparative genomic hybridization in three children with tethered spinal cord syndrome and two healthy parents. Of eight copy number variations, four were non-polymorphic. These non-polymorphic copy number variations were associated with Angelman and Prader-Willi syndromes, and microcephaly. Gene function enrichment analysis revealed that COX8C, a gene associated with metabolic disorders of the nervous system, was located in the copy number variation region of Patient 1. Our results indicate that array-based comparative genomic hybridization can be used to diagnose tethered spinal cord syndrome. Our results may help determine the pathogenesis of tethered spinal cord syndrome and prevent occurrence of this disease.

  14. Gonadoblastomas in 45,X/46,XY mosaicism: analysis of Y chromosome distribution by fluorescence in situ hybridization.

    Science.gov (United States)

    Iezzoni, J C; Von Kap-Herr, C; Golden, W L; Gaffey, M J

    1997-08-01

    Gonadoblastomas are composed of nests of neoplastic germ cells and sex cord derivatives surrounded by ovarian-type stroma. These tumors are found almost exclusively in persons with gonadal dysgenesis associated with a Y chromosome or Y chromosome fragment, and accordingly, the Y chromosome has been implicated in gonadoblastoma oncogenesis. To evaluate this association, we used two-color fluorescence in situ hybridization with chromosome-specific probes to determine the distribution of the X and Y chromosomes in the tumor nests and surrounding stromal cells in paraffin tissue sections of three gonadoblastomas in two patients with gonadal dysgenesis and 45,X/46,XY mosaicism. Statistical analysis of the data from the fluorescence in situ hybridization demonstrated that in all three gonadoblastomas, the proportion of nuclei with a Y chromosome signal was significantly higher in the tumor cells than in the nontumoral cells of the surrounding stroma (P<.001). These results suggest that Y chromosome material participates in gonadoblastoma tumorigenesis.

  15. RAPD-based genetic analysis of offsprings from the sexual cross using allotetraploid citrus somatic hybrid as pollen parent

    Institute of Scientific and Technical Information of China (English)

    YI HuaLin; DENG XiuXin

    2007-01-01

    Huazhong Agricultural University, Wuhan 430070, ChinaThirty-one polymorphic decamer primers were selected to genotype 92 progenies from the cross between Yiben No,4, a monoembryonic diploid F1 hybrid of Citrus reticulata Blanco cv Huanongbendizao tangerine and C. ichangensis Swingle, and [Hamlin sweet orange + Rough lemon], an allotetraploid somatic hybrid of Citrus sinensis Osbeck cv. Hamlin and C. jambhiri Lush cv. Rough Lemon. x2(Chi-square) analysis of RAPD markers in the progenies indicated they were randomly transmitted from the four donor parents, without significant difference between the diploids and triploids. However,these progenies were clustered into three major groups using dendrogram constructed by UPGMA,skewed to three parents in certain degrees, 15 (13 triploids and 2 diploids) to Hamlin, 16 (9 and 7) to Yiben No. 4, and 61 (57 and 4) to [Hamlin sweet orange + Rough Lemon] from which genomic contribution was predominant in progenies, respectively.

  16. RAPD-based genetic analysis of offsprings from the sexual cross using allotetraploid citrus somatic hybrid as pollen parent

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Thirty-one polymorphic decamer primers were selected to genotype 92 progenies from the cross be- tween Yiben No.4, a monoembryonic diploid F1 hybrid of Citrus reticulata Blanco cv Huanongbendizao tangerine and C. ichangensis Swingle, and [Hamlin sweet orange + Rough lemon], an allotetraploid somatic hybrid of Citrus sinensis Osbeck cv. Hamlin and C. jambhiri Lush cv. Rough Lemon. χ2 (Chi-square) analysis of RAPD markers in the progenies indicated they were randomly transmitted from the four donor parents, without significant difference between the diploids and triploids. However, these progenies were clustered into three major groups using dendrogram constructed by UPGMA, skewed to three parents in certain degrees, 15 (13 triploids and 2 diploids) to Hamlin, 16 (9 and 7) to Yiben No. 4, and 61 (57 and 4) to [Hamlin sweet orange + Rough Lemon] from which genomic contribu- tion was predominant in progenies, respectively.

  17. Design, Construction and Effectiveness Analysis of Hybrid Automatic Solar Tracking System for Amorphous and Crystalline Solar Cells

    Directory of Open Access Journals (Sweden)

    Bhupendra Gupta

    2013-10-01

    Full Text Available - This paper concerns the design and construction of a Hybrid solar tracking system. The constructed device was implemented by integrating it with Amorphous & Crystalline Solar Panel, three dimensional freedom mechanism and microcontroller. The amount of power available from a photovoltaic panel is determined by three parameters, the type of solar tracker, materials of solar panel and the intensity of the sunlight. The objective of this paper is to present analysis on the use of two different material of Solar panel like Amorphous & Crystalline in a Solar tracking system at Stationary, Single Axis, Dual Axis & Hybrid Axis solar tracker to have better performance with minimum losses to the surroundings, as this device ensures maximum intensity of sun rays hitting the surface of the panel from sunrise to sunset

  18. Analysis of the Primary Constraint Conditions of an Efficient Photovoltaic-Thermoelectric Hybrid System

    Directory of Open Access Journals (Sweden)

    Guiqiang Li

    2016-12-01

    Full Text Available Electrical efficiency can be increased by combining photovoltaic (PV and the thermoelectric (TE systems. However, a simple and cursory combination is unsuitable because the negative impact of temperature on PV may be greater than its positive impact on TE. This study analyzed the primary constraint conditions based on the hybrid system model consisting of a PV and a TE generator (TEG, which includes TE material with temperature-dependent properties. The influences of the geometric size, solar irradiation and cold side temperature on the hybrid system performance is discussed based on the simulation. Furthermore, the effective range of parameters is demonstrated using the image area method, and the change trend of the area with different parameters illustrates the constraint conditions of an efficient PV-TE hybrid system. These results provide a benchmark for efficient PV-TEG design.

  19. [Plasma temperature calculation and coupling mechanism analysis of laser-double wire hybrid welding].

    Science.gov (United States)

    Zheng, Kai; Li, Huan; Yang, Li-Jun; Gu, Xiao-Yan; Gao, Ying

    2013-04-01

    The plasma radiation of laser-double wire hybrid welding was collected by using fiber spectrometer, the coupling mechanism of arc with laser was studied through high-speed photography during welding process, and the temperature of hybrid plasma was calculated by using the method of Boltzmann plot. The results indicated that with laser hybrid, luminance was enhanced; radiation intensity became stronger; arc was attracted to the laser point; cross section contracted and arc was more stable. The laser power, welding current and arc-arc distance are important factors that have great influence on electron temperature. Increase in the laser power, amplification of welding current and reduction of arc-arc distance can all result in the rise of temperature.

  20. Telomere analysis of platyhelminths and acanthocephalans by FISH and Southern hybridization.

    Science.gov (United States)

    Bombarová, Marta; Vítková, Magda; Spakulová, Marta; Koubková, Bozena

    2009-11-01

    We examined the composition of telomeres in chromosomes of parasitic worms, representatives of the flatworm groups Monogenea and Cestoda (Platyhelminthes), and thorny-headed worms (Syndermata: Acanthocephala) by fluorescence in situ hybridization (FISH) with different telomeric repeat probes. Our results show that the (TTAGGG)n sequence, supposed to be the ancestral telomeric repeat motif of Metazoa, is conserved in Monogenea (Paradiplozoon homoion) and Cestoda (Caryophyllaeus laticeps, Caryophyllaeides fennica, and Nippotaenia mogurndae) but not in Acanthocephala (Pomphorhynchus laevis and Pomphorhynchus tereticollis). In the Pomphorhynchus species, no hybridization signals were obtained with the "nematode" (TTAGGC)n, "arthropod" (TTAGG)n, and bdelloid (TGTGGG)n telomeric probes using FISH with their chromosomes and Southern hybridization with P. laevis DNA. Therefore, we suggest that parasitic Acanthocephala have evolved yet unknown telomeric repeat motifs or different mechanisms of telomere maintenance.

  1. Analysis of merits of hybrid wind/photovoltaic concept for stand-alone systems

    Science.gov (United States)

    Castle, J. A.; Kallis, J. M.; Moite, S. M.; Marshall, N. A.

    Methods for evaluating the merits of hybrid wind/photovoltaic systems for use in stand-alone applications were developed. The optimum mix of wind and photovoltaic power with an electrochemical storage system, with or without fossil fuel generator backup, depends upon the individual subsystem economics. A computer code was developed to calculate the optimum subsystem sizes that minimize the levelized energy cost. The actual merits of a hybrid system over a pure photovoltaic or wind system depend upon many factors: load profile; wind regime; insolation; cost and availability of backup power; the relative costs of wind rotor area, array area, and storage; and subsystem efficiency factors. Examples of optimized hybrid systems for a range of photovoltaic costs and estimated wind and storage costs are shown for an Ely, NV, application, where backup power is allowed to supply 5% of the total annual load.

  2. A Comprehensive Performance Analysis of Proactive, Reactive and Hybrid MANETs Routing Protocols

    CERN Document Server

    Pandey, Kavita

    2011-01-01

    A mobile Ad-hoc network (MANET) is a dynamic multi hop wireless network established by a group of nodes in which there is no central administration. Due to mobility of nodes and dynamic network topology, the routing is one of the most important challenges in ad-hoc networks. Several routing algorithms for MANETs have been proposed by the researchers which have been classified into various categories, however, the most prominent categories are proactive, reactive and hybrid. The performance comparison of routing protocols for MANETs has been presented by other researcher also, however, none of these works considers proactive, reactive and hybrid protocols together. In this paper, the performance of proactive (DSDV), reactive (DSR and AODV) and hybrid (ZRP) routing protocols has been compared. The performance differentials are analyzed on the basis of throughput, average delay, routing overhead and number of packets dropped with a variation of number of nodes, pause time and mobility.

  3. Fast structural design and analysis via hybrid domain decomposition on massively parallel processors

    Science.gov (United States)

    Farhat, Charbel

    1993-01-01

    A hybrid domain decomposition framework for static, transient and eigen finite element analyses of structural mechanics problems is presented. Its basic ingredients include physical substructuring and /or automatic mesh partitioning, mapping algorithms, 'gluing' approximations for fast design modifications and evaluations, and fast direct and preconditioned iterative solvers for local and interface subproblems. The overall methodology is illustrated with the structural design of a solar viewing payload that is scheduled to fly in March 1993. This payload has been entirely designed and validated by a group of undergraduate students at the University of Colorado using the proposed hybrid domain decomposition approach on a massively parallel processor. Performance results are reported on the CRAY Y-MP/8 and the iPSC-860/64 Touchstone systems, which represent both extreme parallel architectures. The hybrid domain decomposition methodology is shown to outperform leading solution algorithms and to exhibit an excellent parallel scalability.

  4. Practical Switching-Based Hybrid FSO/RF Transmission and Its Performance Analysis

    KAUST Repository

    Usman, Muneer

    2014-10-01

    Hybrid free-space optical (FSO)/radio-frequency (RF) systems have emerged as a promising solution for high-data-rate wireless backhaul. We present and analyze a switching-based transmission scheme for the hybrid FSO/RF system. Specifically, either the FSO or RF link will be active at a certain time instance, with the FSO link enjoying a higher priority. We considered both a single-threshold case and a dual-threshold case for FSO link operation. Analytical expressions have been obtained for the outage probability, average bit error rate, and ergodic capacity for the resulting system. Numerical examples are presented to compare the performance of the hybrid scheme with the FSO-only scenario.

  5. Fluorescence in situ hybridization analysis of formalin fixed paraffin embedded tissues, including tissue microarrays.

    Science.gov (United States)

    Summersgill, Brenda M; Shipley, Janet M

    2010-01-01

    Formalin fixed paraffin embedded (FFPE) material is frequently the most convenient readily available source of diseased tissue, including tumors. Multiple cores of FFPE material are being used increasingly to construct tissue microarrays (TMAs) that enable simultaneous analyses of many archival samples. Fluorescence in situ hybridization (FISH) is an important approach to analyze FFPE material for specific genetic aberrations that may be associated with tumor types or subtypes, cellular morphology, and disease prognosis. Annealing, or hybridization of labeled nucleic acid sequences, or probes, to detect and locate one or more complementary nucleic acid sequences within fixed tissue sections allows the detection of structural (translocation/inversion) and numerical (deletion/gain) aberrations and their localization within tissues. The robust protocols described include probe preparation, hybridization, and detection and take 2-3 days to complete. A protocol is also described for the stripping of probes for repeat FISH in order to maximize the use of scarce tissue resources.

  6. Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids.

    Science.gov (United States)

    Qu, K-X; He, Z-X; Nie, W-H; Zhang, J-C; Jin, X-D; Yang, G-R; Yuan, X-P; Huang, B-Z; Zhang, Y-P; Zan, L-S

    2012-01-19

    We examined the cytogenetics of mithun (Bos frontalis), a domesticated version of the Asian gaur, and hybrids (F(1) generation) produced by artificial insemination of Brahman cows (Bos indicus) with mithun semen. Reproductive potential was also examined in the F(1) generation and a backcrossed heifer for utilization of heterosis. Metaphase chromosome spreads were examined by conventional staining and fluorescence in situ hybridization hybridized with the entire chromosome 1 of mithun as a specific probe. Chromosome 1 of mithun was found to be equivalent to Bos taurus chromosomes 2 and 28. The karyotype of the female mithun (N = 4) comprised 58 chromosomes, including 54 acrocentric and four large submetacentric chromosomes, without the four acrocentric chromosomes found in the domesticated species B. indicus. However, one of the four female mithuns with a normal mithun phenotype had an abnormal karyotype (2n = 59), indicating introgression from B. taurus or B. indicus. The F(1) karyotypes (N = 6, 3♂3♀) of the mithun bull × Brahman cow cross had 2n = 59, intermediate between their parents; they were consistent heterozygous carriers with a centric fusion involving rob(2;28), as expected. Two pronounced red signals were seen in the mithun karyotypes, three red signals in the mithun × Brahman hybrids, and four red signals in the Brahman cattle, in good agreement with centric fusion of bovine rob(2;28). The female backcross hybrid (N = 1) with 2n = 59 had a similar chromosome configuration to the F(1) karyotypes and had rob(2;28). Such female backcross hybrids normally reproduce; however, the F(1) bulls (N = 3) had not yet generated normal sperm at 24 months.

  7. Fabrication, testing, and analysis of anisotropic carbon/glass hybrid composites: volume 1: technical report.

    Energy Technology Data Exchange (ETDEWEB)

    Wetzel, Kyle K. (Wetzel Engineering, Inc. Lawrence, Kansas); Hermann, Thomas M. (Wichita state University, Wichita, Kansas); Locke, James (Wichita state University, Wichita, Kansas)

    2005-11-01

    Anisotropic carbon/glass hybrid composite laminates have been fabricated, tested, and analyzed. The laminates have been fabricated using vacuum-assisted resin transfer molding (VARTM). Five fiber complexes and a two-part epoxy resin system have been used in the study to fabricate panels of twenty different laminate constructions. These panels have been subjected to physical testing to measure density, fiber volume fraction, and void fraction. Coupons machined from these panels have also been subjected to mechanical testing to measure elastic properties and strength of the laminates using tensile, compressive, transverse tensile, and in-plane shear tests. Interlaminar shear strength has also been measured. Out-of-plane displacement, axial strain, transverse strain, and inplane shear strain have also been measured using photogrammetry data obtained during edgewise compression tests. The test data have been reduced to characterize the elastic properties and strength of the laminates. Constraints imposed by test fixtures might be expected to affect measurements of the moduli of anisotropic materials; classical lamination theory has been used to assess the magnitude of such effects and correct the experimental data for the same. The tensile moduli generally correlate well with experiment without correction and indicate that factors other than end constraints dominate. The results suggest that shear moduli of the anisotropic materials are affected by end constraints. Classical lamination theory has also been used to characterize the level of extension-shear coupling in the anisotropic laminates. Three factors affecting the coupling have been examined: the volume fraction of unbalanced off-axis layers, the angle of the off-axis layers, and the composition of the fibers (i.e., carbon or glass) used as the axial reinforcement. The results indicate that extension/shear coupling is maximized with the least loss in axial tensile stiffness by using carbon fibers oriented 15{sup

  8. Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis

    Science.gov (United States)

    Millis, Sherri Z.; Kimbrough, Jeffery; Doll, Nancy; Von Hoff, Daniel; Ramanathan, Ramesh K.

    2017-01-01

    Background Appendiceal cancers are rare and consist of carcinoid, mucocele, pseudomyxoma peritonei (PMP), goblet cell carcinoma, lymphoma, and adenocarcinoma histologies. Current treatment involves surgical resection or debulking, but no standard exists for adjuvant chemotherapy or treatment for metastatic disease. Methods Samples were identified from approximately 60,000 global tumors analyzed at a referral molecular profiling CLIA-certified laboratory. A total of 588 samples with appendix primary tumor sites were identified (male/female ratio of 2:3; mean age =55). Sixty-two percent of samples were adenocarcinomas (used for analysis); the rest consisted of 9% goblet cell, 15% mucinous; 6% pseudomyxoma, and less than 5% carcinoids and 2% neuroendocrine. Tests included sequencing [Sanger, next generation sequencing (NGS)], protein expression/immunohistochemistry (IHC), and gene amplification [fluorescent in situ hybridization (FISH) or CISH]. Results Profiling across all appendiceal cancer histological subtypes for IHC revealed: 97% BRCP, 81% MRP1, 81% COX-2, 71% MGMT, 56% TOPO1, 5% PTEN, 52% EGFR, 40% ERCC1, 38% SPARC, 35% PDGFR, 35% TOPO2A, 25% RRM1, 21% TS, 16% cKIT, and 12% for TLE3. NGS revealed mutations in the following genes: 50.4% KRAS, 21.9% P53, 17.6% GNAS, 16.5% SMAD4, 10% APC, 7.5% ATM, 5.5% PIK3CA, 5.0% FBXW7, and 1.8% BRAF. Conclusions Appendiceal cancers show considerable heterogeneity with high levels of drug resistance proteins (BCRP and MRP1), which highlight the difficulty in treating these tumors and suggest an individualized approach to treatment. The incidence of low TS (79%) could be used as a backbone of therapy (using inhibitors such as 5FU/capecitabine or newer agents). Therapeutic options includeTOPO1 inhibitors (irinotecan/topotecan), EGFR inhibitors (erlotinib, cetuximab), PDGFR antagonists (regorafenib, axitinib), MGMT (temozolomide). Clinical trials targeting pathways involving KRAS, p53, GNAS, SMAD4, APC, ATM, PIK3CA, FBXW7, and

  9. Analysis of Non-Conventional Hybrid MOSFET Structure for Gate Leakage Current

    Directory of Open Access Journals (Sweden)

    RANA Ashwani K.

    2011-10-01

    Full Text Available A non-conventional hybrid MOSFET (HMOSstructure has been proposed to reduce the gate leakagecurrent. This non-conventional hybrid MOSFET consistsof source/drain-to-gate non-overlap region and high-kgate stack. The gate leakage behaviour of HMOS hasbeen investigated with the help of compact analyticalmodel, which is backed by Sentaurus Simulation. Ourmodel sustains a very good agreement between the modeland TCAD result. It is found that HMOS structure hasreduced the gate leakage current to great extent ascompared to conventional overlapped MOSFETstructure.

  10. Three thermal analysis models for laser, GMAW-P and Iaser+GMAW-P hybrid welding

    Institute of Scientific and Technical Information of China (English)

    XU Guoxiang; WU Chuansong; QIN Guoliang; WANG Xuyou; LIN Shangyang

    2009-01-01

    The temperature fields and the weld pool geometries for laser + GMA W-P hybrid welding, laser welding and pulsed gas metal arc welding (GMAW-P) are numerically simulated in quasi-steady state by using the developed heat source models, respectively. The calculated weld cross-sections of the three types of welding processes agree well with their respective measured results. Through comparison, it is found that the temperature distribution of laser+ GMAW-P hybrid welding possesses the advantages of those in both laser and GMA W-P welding processes so that the improvement of welding productivity and weld quality are ensured.

  11. Inverse kinematics analysis and numerical control experiment for PRS-XY style hybrid machining tool

    Institute of Scientific and Technical Information of China (English)

    JIA Dongyong; ZHANG Jianmin; NIU Zhigang; SUN Hongchang

    2007-01-01

    This paper analyzed the inverse kinematics for the new Parallel rotate slider-X Y axes(PRS-XY)style hybrid machining tool and educed the five axes linkage inverse kinematics transform formula on the basis of the coordinates of the X,Y,Z,A and B virtual axes.The program for the PRS-XY style hybrid machining tool in accordance with the program manner for the common numerical control(NC)machine tool was made.The results of the experiments prove that the inverse kinematics transform formula is correct.

  12. Approximate discrete time analysis of the hybrid Token-CDMA MAC system

    CSIR Research Space (South Africa)

    Liu, YS

    2007-09-01

    Full Text Available of the Hybrid Token-CDMA MAC System Yi Sheng Liu, Student Member, IEEE, Fambirai Takawira, Member, IEEE , and Hong Jun Xu, Member, IEEE Abstract— In this paper a hybrid Token-CDMA based medium access control (MAC) protocol is considered. The MAC scheme...Zulu-Natal, Howard College Campus. He received the BSc degree in 1984 from the University of Guilin Technology and the MSc degree from the Institute of Telecontrol and Telemeasure in Shi Jian Zhuang, 1989, and the PhD degree from the Beijing University...

  13. Analysis of experimental mink enteritis virus infection in mink: in situ hybridization, serology, and histopathology

    DEFF Research Database (Denmark)

    Uttenthal, Åse; Larsen, S; Lund, E;

    1990-01-01

    Strand-specific hybridization probes were used in in situ hybridization studies to localize cells containing mink enteritis virus (MEV) virion DNA or MEV replicative-form DNA and mRNA. Following the experimental MEV infection of 3-month-old unvaccinated mink, a significant increase in serum antib...... parvoviruses is discussed....... important implications for the pathogenesis of MEV-induced disease. The data presented on MEV are correlated with earlier results on the other mink parvovirus, Aleutian mink disease parvovirus, and a possible explanation for the remarkable differences in pathogenesis of disease caused by these two...

  14. Analysis on the crossing obstacle of wheel-track hybrid mobile robot

    Institute of Scientific and Technical Information of China (English)

    帅立国

    2016-01-01

    A novel wheel-track hybrid mobile robot with many movement patterns is designed.According to different environments,it can switch between the pure wheel pattern and the pure track one.Ac-cording to a homogeneous coordinate transformation matrix, gravity stability and its obstacle perform-ance are analyzed.Its gravity equation and climbing obstacle conditions are established.Experimen-tal results show that this hybrid mobile robot could fully possess the advantages of both the wheel and the track mechanisms and achieve a good obstacle climbing capability.

  15. Evidence for non-disomic inheritance in a Citrus interspecific tetraploid somatic hybrid between C. reticulata and C. limon using SSR markers and cytogenetic analysis.

    Science.gov (United States)

    Kamiri, Mourad; Stift, Marc; Srairi, Ikbal; Costantino, Gilles; El Moussadik, Abdelhamid; Hmyene, Abdelaziz; Bakry, Frédéric; Ollitrault, Patrick; Froelicher, Yann

    2011-08-01

    Artificial tetraploid somatic hybrids have been developed for sterile triploid citrus breeding by sexual hybridization between diploid and tetraploid somatic hybrids. The genetic structure of diploid gametes produced by tetraploid genotypes depends on the mode of chromosome association at meiosis. In order to evaluate tetraploid inheritance in a tetraploid interspecific somatic hybrid between mandarin and lemon, we performed segregation studies using cytogenetic and single sequence repeat molecular markers. Cytogenetic analysis of meiosis in the somatic hybrid revealed 11% tetravalents and 76% bivalents. Inheritance of the tetraploid hybrid was analyzed by genotyping the triploid progeny derived from a cross between a diploid pummelo and the tetraploid somatic hybrid, in order to derive genotypes of the meiospores produced by the tetraploid. A likelihood-based approach was used to distinguish between disomic, tetrasomic, and intermediate inheritance models and to estimate the double reduction rate. In agreement with expectations based the cytogenetic data, marker segregation was largely compatible with tetrasomic and inheritance intermediate between disomic and tetrasomic, with some evidence for preferential pairing of homoeologous chromosomes. This has important implications for the design of breeding programs that involve tetraploid hybrids, and underscores the need to consider inheritance models that are intermediate between disomic and tetrasomic.

  16. Assessing hybrid sterility in Oryza glaberrima x O. sativa hybrid progenies by PCR marker analysis and crossing with wide compatibility varieties.

    Science.gov (United States)

    Heuer, Sigrid; Miézan, Kouamé M

    2003-09-01

    Interspecific crossing of the African indigenous rice Oryza glaberrima with Oryza sativa cultivars is hindered by crossing barriers causing 100% spikelet sterility in F(1) hybrids. Since hybrids are partially female fertile, fertility can be restored by back crossing (BC) to a recurrent male parent. Distinct genetic models on spikelet sterility have been developed predicting, e.g., the existence of a gamete eliminator and/or a pollen killer. Linkage of sterility to the waxy starch synthase gene and the chromogen gene C, both located on chromosome 6, have been demonstrated. We selected a segregating BC(2)F(3) population of semi-sterile O. glaberrima x O. sativa indica hybrid progenies for analyses with PCR markers located at the respective chromosome-6 region. These analyses revealed that semi-sterile plants were heterozygous for a marker (OSR25) located in the waxy promoter, whereas fertile progenies were homozygous for the O. glaberrima allele. Adjacent markers showed no linkage to spikelet sterility. Semi-sterility of hybrid progenies was maintained at least until the F(4) progeny generation, suggesting the existence of a pollen killer in this plant material. Monitoring of reproductive plant development showed that spikelet sterility was at least partially due to an arrest of pollen development at the microspore stage. In order to address the question whether genes responsible for F(1) sterility in intraspecific hybrids ( O. sativa indica x japonica) also cause spikelet sterility in interspecific hybrids, crossings with wide compatibility varieties (WCV) were performed. WCV accessions possess "neutral" S-loci ( S(n)) improving fertility in intraspecific hybrids. This experiment showed that the tested S(n)-loci had no fertility restoring effect in F(1) interspecific hybrids. Pollen development was completely arrested at the microspore stage and grains were never obtained after selfing. This suggests that distinct or additional S-loci are responsible for sterility

  17. Experimental-numerical analysis of the fracture mechanic in polymeric materials; Analisis numerico-experimental de la mecanica de la fractura en materiales polimeros

    Energy Technology Data Exchange (ETDEWEB)

    Beltran Fernandez, Juan Alfonso; Hernandez Gomez, Luis H; Urriolagoitia Calderon, Guillermo; Villa y Rabasa, Gabriel; Rodriguez, Gustavo Ricardo; Mendoza Nunez, Maribel A [Instituto Politecnico Nacional, Zacatenco (Mexico)

    2004-10-15

    In this piece of work some fracture testings on specimens with a lateral fracture are made to analyze the resultant stress state around of the tip of the fracture and the way in which the strength of the material is modified to get the fracture toughness, to the load mode I. Also, it is explained the way in which mechanic properties were got in the Polymetil-Methacylate, (PMMA), such as: modulus of elasticity, maximum tensile stress, yielding stress and stress-unitary strain, stress-rate and strain-rate curves, throughout of the carry out of the tensile testing. With the objective to know the real mechanical behavior with the initial loading conditions established and different testing velocities. All and each one of the results are calculated experimental and numerically and validated throughout of the finite element method, using the software ANSYS 5.5.3. [Spanish] En este trabajo se efectuan pruebas de fractura en especimenes con una grieta lateral, para analizar el estado de esfuerzos resultantes alrededor de la punta de la grieta y la forma en que se afecta la resistencia del material a fin de obtener la tenacidad de fractura para el modo de carga I. Ademas, se explica la forma como se obtienen las propiedades mecanicas en el polimetil metacrilato (PMMA), tales como: modulo de elasticidad, esfuerzo normal maximo, esfuerzo de cadencia y las curvas esfuerzo-deformacion unitaria, esfuerzo-tiempo (stress-rate) y deformacion-tiempo (strain-rate), a traves de la realizacion de la prueba de tension. Se busca conocer el comportamiento mecanico real ante las condiciones de carga establecidas y a distintas velocidades de prueba. Todo y cada uno de los resultados se efectuan de manera experimental y son evaluados numericamente a traves del metodo del elemento finito, con el programa ANSYS 5.5.3.

  18. Comparative cost analysis of hybrid striped bass fingerling production in ponds and tanks

    Science.gov (United States)

    Year-round production of hybrid striped bass (female white bass Morone chrysops×male striped bass M. saxatilis) fingerlings would allow food fish growers to sell their product throughout the year, which would improve the consistency of market supply and cash flow for the farm. However, pond producti...

  19. Position Analysis of a Hybrid Serial-Parallel Manipulator in Immersion Lithography

    Directory of Open Access Journals (Sweden)

    Jie-jie Shao

    2015-01-01

    Full Text Available This paper proposes a novel hybrid serial-parallel mechanism with 6 degrees of freedom. The new mechanism combines two different parallel modules in a serial form. 3-P̲(PH parallel module is architecture of 3 degrees of freedom based on higher joints and specializes in describing two planes’ relative pose. 3-P̲SP parallel module is typical architecture which has been widely investigated in recent researches. In this paper, the direct-inverse position problems of the 3-P̲SP parallel module in the couple mixed-type mode are analyzed in detail, and the solutions are obtained in an analytical form. Furthermore, the solutions for the direct and inverse position problems of the novel hybrid serial-parallel mechanism are also derived and obtained in the analytical form. The proposed hybrid serial-parallel mechanism is applied to regulate the immersion hood’s pose in an immersion lithography system. Through measuring and regulating the pose of the immersion hood with respect to the wafer surface simultaneously, the immersion hood can track the wafer surface’s pose in real-time and the gap status is stabilized. This is another exploration to hybrid serial-parallel mechanism’s application.

  20. Diallel analysis of popcorn lines and hybrids for baby corn production

    Directory of Open Access Journals (Sweden)

    Lucas Rafael de Souza Camacho

    2015-03-01

    Full Text Available The aim of this study was to evaluate the combining ability of popcorn lines and hybrids with favorable traits for baby corn production, using lines extracted from the major genotypes of the Brazilian germplasm. From nine popcorn lines, derived from the genotypes Zélia, CMS 42, CMS 43, UEM M2, Zaeli and IAC 112, 36 single-cross hybrids were obtained without reciprocals. In partial diallel crosses, 25 single-cross hybrids were obtained, derived from crosses of five lines of the Zaeli (group I with five lines from IAC 112 (group II. We recommend using lines derived from Zaeli and CMS 42 in hybrid breeding programs for higher ear yields. The lines P9.5.1 and P9.5.5 (group I and P8.3 and P8.5 (group II can be recommended for recombination within each group and for the formation of two synthetic populations for recurrent selection, in order to increase ear yield.

  1. Analysis of hepcidin expression: in situ hybridization and quantitative polymerase chain reaction from paraffin sections.

    Science.gov (United States)

    Sakuraoka, Yuhki; Sawada, Tokihiko; Shiraki, Takayuki; Park, Kyunghwa; Sakurai, Yuhichiro; Tomosugi, Naohisa; Kubota, Keiichi

    2012-07-28

    To establish methods for quantitative polymerase chain reaction (PCR) for hepcidin using RNAs isolated from paraffin-embedded sections and in situ hybridization of hepatocellular carcinoma (HCC). Total RNA from paraffin-embedded sections was isolated from 68 paraffin-embedded samples of HCC. Samples came from 54 male and 14 female patients with a mean age of 66.8 ± 7.8 years. Quantitative PCR was performed. Immunohistochemistry and in situ hybridization for hepcidin were also performed. Quantitative PCR for hepcidin using RNAs isolated from paraffin-embedded sections of HCC was performed successfully. The expression level of hepcidin mRNA in cancer tissues was significantly higher than that in non-cancer tissues. A method of in situ hybridization for hepcidin was established successfully, and this demonstrated that hepcidin mRNA was expressed in non-cancerous tissue but absent in cancerous tissue. We have established novel methods for quantitative PCR for hepcidin using RNAs isolated from paraffin-embedded sections and in situ hybridization of HCC.

  2. Numerical Analysis of Energy Effect in Laser-TIG Hybrid Welding

    Institute of Scientific and Technical Information of China (English)

    Yanbin CHEN; Liqun LI; Junfei FANG; Xiaosong FENG

    2003-01-01

    The hybrid source that combined CO2 laser with TIG arc to proceed welding was analyzed. Based on an energymodel, the temperature field and weld shape were calculated numerically. The heat transfer characteristic of thehybrid heat source to workpiece and i

  3. Performance Analysis of Hybrid Distribution in Human-Centric Multimedia Networking

    Institute of Scientific and Technical Information of China (English)

    HU Yuxiang; DONG Fang; LAN Julong

    2016-01-01

    With the booming of Human-centric mul-timedia networking (HMN), there are rising amount of human-made multimedia that needs to distribute to con-sumers with higher speed and efficiency. Hybrid distribu-tion of Client/Server (C/S) and Peer-to-Peer (P2P) have been successfully deployed on the Internet and the practi-cal benefits have been widely reported, while its theoretical performance remains unknown for mass data delivery un-fortunately. This paper presents an analytical and experi-mental study on the performance of accelerating large-scale hybrid distribution over the Internet. In particular, this pa-per focuses on the user behavior in HMN and establishes a user behavior model based on the Kermack-McKendrick model in epidemiology. Analytical expressions of average delay in HMN are then derived based on C/S, P2P and hy-brid distribution, respectively. Our simulation shows how to design and deploy a hybrid distribution system of HMN that helps to bridge the gap between system ultilization and quality of service, which provides direct guidance for practical system design.

  4. Analysis of hepcidin expression: In situ hybridization and quantitative polymerase chain reaction from paraffin sections

    Institute of Scientific and Technical Information of China (English)

    Yuhki Sakuraoka; Tokihiko Sawada; Takayuki Shiraki; Kyunghwa Park; Yuhichiro Sakurai; Naohisa Tomosugi; Keiichi Kubota

    2012-01-01

    AIM:TO establish methods for quantitative polymerase chain reaction (PCR) for hepcidin using RNAs isolated from paraffin-embedded sections and in situ hybridization of hepatocellular carcinoma (HCC).METHODS:Total RNA from paraffin-embedded sections was isolated from 68 paraffin-embedded samples of HCC.Samples came from 54 male and 14 female patients with a mean age of 66.8 ± 7.8 years.Quantitative PCR was performed.Immunohistochemistry and in situ hybridization for hepcidin were also performed.RESULTS:Quantitative PCR for hepcidin using RNAs isolated from paraffin-embedded sections of HCC was performed successfully.The expression level of hepcidin mRNA in cancer tissues was significantly higher than that in non-cancer tissues.A method of in situ hybridization for hepcidin was established successfully,and this demonstrated that hepcidin mRNA was expressed in non-cancerous tissue but absent in cancerous tissue.CONCLUSION:We have established novel methods for quantitative PCR for hepcidin using RNAs isolated from paraffin-embedded sections and in situ hybridization of HCC.

  5. Comparative analysis of inbred and hybrid maize at the diploid and tetraploid levels.

    Science.gov (United States)

    Riddle, Nicole C; Birchler, James A

    2008-02-01

    Heterosis often occurs in offspring derived from a cross between inbred or divergent parents and can be observed as the superior performance of these hybrids for a wide variety of characters. Heterosis was compared in maize lines at two ploidy levels, diploid and tetraploid, to gain a better understanding of the interaction of heterosis and ploidy level. Employing genetically identical diploid and tetraploid maize derived from four different inbred lines, we investigated heterosis for 11 morphological traits, including several plant height measures, as well as flowering time for both silks and anthers. We find that the heterotic response of a certain hybrid differs between diploid and tetraploid lines, and that the response at one ploidy cannot serve as a predictor for the other. Also, progressive heterosis was found for several of the characters in the tetraploid double-cross hybrid, which can have four different alleles at one locus, compared to the double-cross diploid hybrids, which can only possess two alleles per locus. Overall, the results indicate that the heterotic response of tetraploid maize lines differs significantly from that of the diploid.

  6. Machine Vision Analysis of Characteristics and Image Information Base Construction for Hybrid Rice Seed

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Incompletely closed glumes, germination on panicle and disease ara thrae important factors causing poor seed quality of hybrid rice. To determine how many and which categories should be classified to meet the demand for seed in rice production, the effects of various degrees of incompletely closed glumes, germination on panicle and disease on germination percentage at the harvest and after storage for six months were studied by standard germination percentage test. Six categories of seeds with germ (germinated seeds), severe disease, incompletely closed glumes, spot disease, fine fissure and normal seeds were inspected and then treated separately. Images of the five hybrid rice seed (Jinyou 402, Shanyou 10, Zhongyou 27, Jiayou 99 and Ⅱ you 3207) were acquired with a self-developed machine vision system. Each image could be processed to get the feature values of seed region such as length, width, ratio of length to width, araa, solidity and hue. Then all the images of normal seeds were calculated to draw the feature value ranges of each hybrid rice variety. Finally, an image information base that stores typical images and related feature values of each variety was established. This image information base can help us to identify the classification limit of characteristics, and provide the reference of the threshold selection. The management of large numbers of pictures and the addition of new varieties have been supported. The research laid a foundation for extracting image features of hybrid rice seed, which is a key approach to futura quality inspection with machine vision.

  7. Interphase cytogenetic analysis of prostatic carcinomas by use of nonisotopic in situ hybridization.

    Science.gov (United States)

    Baretton, G B; Valina, C; Vogt, T; Schneiderbanger, K; Diebold, J; Löhrs, U

    1994-08-15

    To gain a better understanding of chromosomal aberrations in direct correlation with histology, we studied tumor material from 35 patients (36 regions) with primary prostate carcinoma by nonisotopic in situ hybridization. Nine biotinylated DNA probes were used on serial paraffin sections (centromer-specific probes for X, Y, 1, 7, 8, 10, 17, and 18, and a telomer-specific probe for 1p; ONCOR). Of the 324 hybridized sections, 94% were suitable for evaluation. In 34 of the 35 cases (35 of 36 regions) 1-8 chromosomal aberrations were detected. Chromosome X showed supernumerary centromer copies in 44% of cases. The probes for chromosomes 1, 1p, 10, and 18 demonstrated deletions in 25, 23, 40 and 58% of cases, respectively. Gains as well as deletions were present for Y, 7, 8, and 17 in 31, 25, 36, and 58% of cases, respectively. In 27% of cases discordant copy numbers of the centromer- and the telomer-specific probes for chromosome 1 were observed. No aberration which might be specific for prostate cancer could be established. The rate of aneusomy increased significantly with histological grade. Intratumoral heterogeneity of chromosomal aberrations was revealed in one case. Due to the higher sensitivity of nonisotopic in situ hybridization, aneusomic cases outnumbered cases with cytometrically determined DNA aneuploidy. In view of published results of metaphase preparations, the high frequency of aneusomy and some of the chromosomal aberrations detected by nonisotopic in situ hybridization were unexpected.

  8. Hybrid composites, state-of-the-art review: Analysis, design, application and fabrication

    Science.gov (United States)

    Chamis, C. C.; Lark, R. F.

    1977-01-01

    The areas of constituents and types of hybrids, analytical methods, design methods, applications, and fabrication procedures are discussed. The review summarizes significant contributions in each area and points out areas for further research. The description of each significant contribution is supplemented with pertinent illustrations and references.

  9. Numerical and experimental analysis of heat transfer in injector plate of hydrogen peroxide hybrid rocket motor

    Science.gov (United States)

    Cai, Guobiao; Li, Chengen; Tian, Hui

    2016-11-01

    This paper is aimed to analyze heat transfer in injector plate of hydrogen peroxide hybrid rocket motor by two-dimensional axisymmetric numerical simulations and full-scale firing tests. Long-time working, which is an advantage of hybrid rocket motor over conventional solid rocket motor, puts forward new challenges for thermal protection. Thermal environments of full-scale hybrid rocket motors designed for long-time firing tests are studied through steady-state coupled numerical simulations of flow field and heat transfer in chamber head. The motor adopts 98% hydrogen peroxide (98HP) oxidizer and hydroxyl-terminated poly-butadiene (HTPB) based fuel as the propellants. Simulation results reveal that flowing liquid 98HP in head oxidizer chamber could cool the injector plate of the motor. The cooling of 98HP is similar to the regenerative cooling in liquid rocket engines. However, the temperature of the 98HP in periphery portion of the head oxidizer chamber is higher than its boiling point. In order to prevent the liquid 98HP from unexpected decomposition, a thermal protection method for chamber head utilizing silica-phenolics annular insulating board is proposed. The simulation results show that the annular insulating board could effectively decrease the temperature of the 98HP in head oxidizer chamber. Besides, the thermal protection method for long-time working hydrogen peroxide hybrid rocket motor is verified through full-scale firing tests. The ablation of the insulating board in oxygen-rich environment is also analyzed.

  10. Analysis methodology for flow-level evaluation of a hybrid mobile-sensor network

    NARCIS (Netherlands)

    Dimitrova, D.C.; Heijenk, G.; Braun, T.

    2011-01-01

    Our society uses a large diversity of co-existing wired and wireless networks in order to satisfy its communication needs. A cooper- ation between these networks can benefit performance, service availabil- ity and deployment ease, and leads to the emergence of hybrid networks. This position paper fo

  11. Techno-economic analysis of biomethanol production via hybrid steam reforming of glycerol with natural gas

    NARCIS (Netherlands)

    Balegedde Ramachandran, P.; Oudenhoven, S.R.G; Kersten, S.R.A.; Rossum, van G.; Ham, van der A.G.J.

    2013-01-01

    The present article deals with the techno-economic assessment of the hybrid steam reforming (HSR) process of glycerol (obtained via transesterification) together with natural gas to produce biomethanol via the synthesis gas route. In this techno-economic assessment, a model is developed in the UniSi

  12. Detection and analysis system for hybridization images of lab-in-a-tube microarray

    Institute of Scientific and Technical Information of China (English)

    LIU Quanjun; ZHOU Qin; BAI Yunfei; GE Qinyu; LU Zuhong

    2005-01-01

    A lab-in-a-tube microarray system is developed for sample inspection and signal detection by fabricating a flat transparent window cap of the Eppendorf tube. The oli- gonucleotide microarray is immobilized on the inner surface of the cap. A small vessel is placed in an Eppendorf tube for storing hybridization solutions. With the microarray system, the full biochemical processes, including gene fragment amplification, fluorescence labeling, hybridization, and fluorescence detection, have been performed in the sealed tube without opening the cap. The images are obtained from a fluorescence microscope and captured by a CCD, and the data are transported to a computer through the universal serial bus (USB). After noise reduction, signal intensity is determined from hybridization image and the presence of gene fragments is identified. The final data output includes sample information, process steps, and hybridization results. A lab-in- a-tube microarray system for detecting ten respiratory viruses at a single detection is designed. High detection throug- hput and accuracy have been demonstrated with the system.

  13. Analysis methodology for flow-level evaluation of a hybrid mobile-sensor network

    NARCIS (Netherlands)

    Dimitrova, D.C.; Heijenk, Gerhard J.; Braun, T.

    2012-01-01

    Our society uses a large diversity of co-existing wired and wireless networks in order to satisfy its communication needs. A cooper- ation between these networks can benefit performance, service availabil- ity and deployment ease, and leads to the emergence of hybrid networks. This position paper

  14. Experimental analysis of SiC-based refractory concrete in hybrid rocket nozzles

    Science.gov (United States)

    D'Elia, Raffaele; Bernhart, Gérard; Hijlkema, Jouke; Cutard, Thierry

    2016-09-01

    Hybrid propulsion represents a good alternative to the more widely used liquid and solid systems. This technology combines some important specifications of the latters, as the possibility of re-ignition, thrust modulation, a higher specific impulse than solid systems, a greater simplicity and a lower cost than liquid systems. Nevertheless the highly oxidizing environment represents a major problem as regards the thermo-oxidation and ablative behavior of nozzle materials. The main goal of this research is to characterize a silicon carbide based micro-concrete with a maximum aggregates size of 800 μm, in a hybrid propulsion environment. The nozzle throat has to resist to a highly oxidizing polyethylene/nitrous oxide hybrid environment, under temperatures up to 2900 K. Three tests were performed on concrete-based nozzles in HERA Hybrid Rocket Motor (HRM) test bench at ONERA. Pressure chamber evolution and observations before and after tests are used to investigate the ablated surface at nozzle throat. Ablation behavior and crack generation are discussed and some improvements are proposed.

  15. Outage Analysis of Practical FSO/RF Hybrid System With Adaptive Combining

    KAUST Repository

    Rakia, Tamer

    2015-08-01

    Hybrid free-space optical (FSO)/radio-frequency (RF) systems have emerged as a promising solution for high-data-rate wireless transmission. We present and analyze a transmission scheme for the hybrid FSO/RF communication system based on adaptive combining. Specifically, only FSO link is active as long as the instantaneous signal-to-noise ratio (SNR) at the FSO receiver is above a certain threshold level. When it falls below this threshold level, the RF link is activated along with the FSO link and the signals from the two links are combined at the receiver using a dual-branch maximal ratio combiner. Novel analytical expression for the cumulative distribution function (CDF) of the received SNR for the proposed hybrid system is obtained. This CDF expression is used to study the system outage performance. Numerical examples are presented to compare the outage performance of the proposed hybrid FSO/RF system with that of the FSO-only and RF-only systems. © 1997-2012 IEEE.

  16. Tomato (Solanum lycopersicum) variety discrimination and hybridization analysis based on the 5S rRNA region.

    Science.gov (United States)

    Sun, Yan-Lin; Kang, Ho-Min; Kim, Young-Sik; Baek, Jun-Pill; Zheng, Shi-Lin; Xiang, Jin-Jun; Hong, Soon-Kwan

    2014-05-04

    The tomato (Solanum lycopersicum) is a major vegetable crop worldwide. To satisfy popular demand, more than 500 tomato varieties have been bred. However, a clear variety identification has not been found. Thorough understanding of the phylogenetic relationship and hybridization information of tomato varieties is very important for further variety breeding. Thus, in this study, we collected 26 tomato varieties and attempted to distinguish them based on the 5S rRNA region, which is widely used in the determination of phylogenetic relations. Sequence analysis of the 5S rRNA region suggested that a large number of nucleotide variations exist among tomato varieties. These variable nucleotide sites were also informative regarding hybridization. Chromas sequencing of Yellow Mountain View and Seuwiteuking varieties indicated three and one variable nucleotide sites in the non-transcribed spacer (NTS) of the 5S rRNA region showing hybridization, respectively. Based on a phylogenetic tree constructed using the 5S rRNA sequences, we observed that 16 tomato varieties were divided into three groups at 95% similarity. Rubiking and Sseommeoking, Lang Selection Procedure and Seuwiteuking, and Acorn Gold and Yellow Mountain View exhibited very high identity with their partners. This work will aid variety authentication and provides a basis for further tomato variety breeding.

  17. Analysis of the mechanical and thermal properties of jute and glass fiber as reinforcement epoxy hybrid composites

    Energy Technology Data Exchange (ETDEWEB)

    Braga, R.A., E-mail: roney.braga@fiat.com.br [FIAT Automóveis S.A., Teardown, CEP 32530-000 Betim, MG (Brazil); Magalhaes, P.A.A., E-mail: pamerico@pucminas.br [PUC—MINAS, Instituto Politécnico, CEP 30535-610 Belo Horizonte, MG (Brazil)

    2015-11-01

    This work describes the study to investigate and compare the mechanical and thermal properties of raw jute and glass fiber reinforced epoxy hybrid composites. To improve the mechanical properties, jute fiber was hybridized with glass fiber. Epoxy resin, jute and glass fibers were laminated in three weight ratios (69/31/0, 68/25/7 and 64/18/19) respectively to form composites. The tensile, flexural, impact, density, thermal and water absorption tests were carried out using hybrid composite samples. This study shows that the addition of jute fiber and glass fiber in epoxy, increases the density, the impact energy, the tensile strength and the flexural strength, but decreases the loss mass in function of temperature and the water absorption. Morphological analysis was carried out to observe fracture behavior and fiber pull-out of the samples using scanning electron microscope. - Highlights: • The work is the study of the mechanical of raw jute and glass fiber with epoxy resin. • The mechanical properties increased with more proportions of glass fibers. • The density of E69-J31-V0 was the lower. • The flexural strength did not have a significant increase. • The water absorption of E69-J31-V0 was the best.

  18. Investigation of the effectiveness of nutrient release from sludge foam after hybrid pretreatment processes by IR analysis and EDX Quantification.

    Science.gov (United States)

    Machnicka, Alicja; Grübel, Klaudiusz

    2016-12-01

    One of the problems in wastewater treatment technologies is the formation of foam/scum. It is thought that filamentous microorganisms are responsible for foam formation and foam elimination/destruction can be carried out by various methods, among which disintegration is included. Hybrid disintegration (chemical decomposition and hydrodynamic cavitation) of foam microorganisms results in the transfer of phosphates, ammonium nitrogen, magnesium and potassium from the foam solids into the liquid phase. Application of both methods as a hybrid pretreatment process caused an increase in the concentration of phosphates of about 650 mg [Formula: see text] L(-1) and ammonium nitrogen of about 30 mg [Formula: see text] L(-1). The concentration of Mg(2+) and K(+) in the solution increased from 6.8 and 26.1 mg Mg(2+) L(-1) to 32.2 and 82.2 mg K(+) L(-1), respectively. The presence of nutrients and metal cations in the solid phase of foam was acknowledged by EDX Quantification. The confirmation of physico-chemical changes and release of cellular matter as a result of cellular lysis (hybrid disintegration) was done by infrared analysis. It was demonstrated that the disintegration of foam permits the removal of a part of nutrients in the form of struvite.

  19. Performance analysis of different ORC configurations for thermal energy and LNG cold energy hybrid power generation system

    Science.gov (United States)

    Sun, Zhixin; Wang, Feng; Wang, Shujia; Xu, Fuquan; Lin, Kui

    2017-01-01

    This paper presents a thermal energy and Liquefied natural gas (LNG) cold energy hybrid power generation system. Performances of four different Organic Rankine cycle (ORC) configurations (the basic, the regenerative, the reheat and the regenerative-reheat ORCs) are studied based on the first and the second law of thermodynamics. Dry organic fluid R245fa is selected as the typical working fluid. Parameter analysis is also conducted in this paper. The results show that regeneration could not increase the thermal efficiency of the thermal and cold energy hybrid power generation system. ORC with the reheat process could produce more specific net power output but it may also reduce the system thermal efficiency. The basic and the regenerative ORCs produce higher thermal efficiency while the regenerative-reheat ORC performs best in the exergy efficiency. A preheater is necessary for the thermal and cold energy hybrid power generation system. And due to the presence of the preheater, there will be a step change of the system performance as the turbine inlet pressure rises.

  20. The use of combining ability analysis to identify elite parents for Artemisia annua F1 hybrid production.

    Directory of Open Access Journals (Sweden)

    Theresa Townsend

    Full Text Available Artemisia annua is an important medicinal crop used for the production of the anti-malarial compound artemisinin. In order to assist in the production of affordable high quality artemisinin we have carried out an A. annua breeding programme aimed at improving artemisinin concentration and biomass. Here we report on a combining ability analysis of a diallel cross to identify robust parental lines for hybrid breeding. The parental lines were selected based on a range of phenotypic traits to encourage heterosis. The general combining ability (GCA values for the diallel parental lines correlated to the positive alleles of quantitative trait loci (QTL in the same parents indicating the presence of beneficial alleles that contribute to parental performance. Hybrids generated from crossing specific parental lines with good GCA were identified as having an increase in both artemisinin concentration and biomass when grown either in glasshouse or experimental field trials and compared to controls. This study demonstrates that combining ability as determined by a diallel cross can be used to identify elite parents for the production of improved A. annua hybrids. Furthermore, the selection of material for breeding using this approach was found to be consistent with our QTL-based molecular breeding approach.

  1. Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β(2,2)-amino acids.

    Science.gov (United States)

    García-González, Iván; Mata, Lara; Corzana, Francisco; Jiménez-Osés, Gonzalo; Avenoza, Alberto; Busto, Jesús H; Peregrina, Jesús M

    2015-01-12

    We synthesized and carried out the conformational analysis of several hybrid dipeptides consisting of an α-amino acid attached to a quaternary glyco-β-amino acid. In particular, we combined a S-glycosylated β(2,2)-amino acid and two different types of α-amino acid, namely, aliphatic (alanine) and aromatic (phenylalanine and tryptophan) in the sequence of hybrid α/β-dipeptides. The key step in the synthesis involved the ring-opening reaction of a chiral cyclic sulfamidate, inserted in the peptidic sequence, with a sulfur-containing nucleophile by using 1-thio-β-D-glucopyranose derivatives. This reaction of glycosylation occurred with inversion of configuration at the quaternary center. The conformational behavior in aqueous solution of the peptide backbone and the glycosidic linkage for all synthesized hybrid glycopeptides was analyzed by using a protocol that combined NMR experiments and molecular dynamics with time-averaged restraints (MD-tar). Interestingly, the presence of the sulfur heteroatom at the quaternary center of the β-amino acid induced θ torsional angles close to 180° (anti). Notably, this value changed to 60° (gauche) when the peptidic sequence displayed aromatic α-amino acids due to the presence of CH-π interactions between the phenyl or indole ring and the methyl groups of the β-amino acid unit.

  2. Passive hybridization of a photovoltaic module with lithium-ion battery cells: A model-based analysis

    Science.gov (United States)

    Joos, Stella; Weißhar, Björn; Bessler, Wolfgang G.

    2017-04-01

    Standard photovoltaic battery systems based on AC or DC architectures require power electronics and controllers, including inverters, MPP tracker, and battery charger. Here we investigate an alternative system design based on the parallel connection of a photovoltaic module with battery cells without any intermediate voltage conversion. This approach, for which we use the term passive hybridization, is based on matching the solar cell's and battery cell's respective current/voltage behavior. A battery with flat discharge characteristics can allow to pin the solar cell to its maximum power point (MPP) independently of the external power consumption. At the same time, upon battery full charge, voltage increase will drive the solar cell towards zero current and therefore self-prevent battery overcharge. We present a modeling and simulation analysis of passively hybridizing a 5 kWp PV system with a 5 kWh LFP/graphite lithium-ion battery. Dynamic simulations with 1-min time resolution are carried out for three exemplary summer and winter days using historic weather data and a synthetic single-family household consumer profile. The results demonstrate the feasibility of the system. The passive hybrid allows for high self-sufficiencies of 84.6% in summer and 25.3% in winter, which are only slightly lower than those of a standard system.

  3. Ka-Band Link Study and Analysis for a Mars Hybrid RF/Optical Software Defined Radio

    Science.gov (United States)

    Zeleznikar, Daniel J.; Nappier, Jennifer M.; Downey, Joseph A.

    2014-01-01

    The integrated radio and optical communications (iROC) project at the NASA Glenn Research Center (GRC) is investigating the feasibility of a hybrid RF and optical communication subsystem for future deep space missions. The hybrid communications subsystem enables the advancement of optical communications while simultaneously mitigating the risk of infusion by combining an experimental optical transmitter and telescope with a reliable Ka-band RF transmitter and antenna. The iROC communications subsystem seeks to maximize the total data return over the course of a potential 2-year mission in Mars orbit beginning in 2021. Although optical communication by itself offers potential for greater data return over RF, the reliable Ka-band link is also being designed for high data return capability in this hybrid system. A daily analysis of the RF link budget over the 2-year span is performed to optimize and provide detailed estimates of the RF data return. In particular, the bandwidth dependence of these data return estimates is analyzed for candidate waveforms. In this effort, a data return modeling tool was created to analyze candidate RF modulation and coding schemes with respect to their spectral efficiency, amplifier output power back-off, required digital to analog conversion (DAC) sampling rates, and support by ground receivers. A set of RF waveforms is recommended for use on the iROC platform.

  4. Multistep Wind Speed Forecasting Using a Novel Model Hybridizing Singular Spectrum Analysis, Modified Intelligent Optimization, and Rolling Elman Neural Network

    Directory of Open Access Journals (Sweden)

    Zhongshan Yang

    2016-01-01

    Full Text Available Wind speed high-accuracy forecasting, an important part of the electrical system monitoring and control, is of the essence to protect the safety of wind power utilization. However, the wind speed signals are always intermittent and intrinsic complexity; therefore, it is difficult to forecast them accurately. Many traditional wind speed forecasting studies have focused on single models, which leads to poor prediction accuracy. In this paper, a new hybrid model is proposed to overcome the shortcoming of single models by combining singular spectrum analysis, modified intelligent optimization, and the rolling Elman neural network. In this model, except for the multiple seasonal patterns used to reduce interferences from the original data, the rolling model is utilized to forecast the multistep wind speed. To verify the forecasting ability of the proposed hybrid model, 10 min and 60 min wind speed data from the province of Shandong, China, were proposed in this paper as the case study. Compared to the other models, the proposed hybrid model forecasts the wind speed with higher accuracy.

  5. Next-generation sequencing analysis of lager brewing yeast strains reveals the evolutionary history of interspecies hybridization.

    Science.gov (United States)

    Okuno, Miki; Kajitani, Rei; Ryusui, Rie; Morimoto, Hiroya; Kodama, Yukiko; Itoh, Takehiko

    2016-02-01

    The lager beer yeast Saccharomyces pastorianus is considered an allopolyploid hybrid species between S. cerevisiae and S. eubayanus. Many S. pastorianus strains have been isolated and classified into two groups according to geographical origin, but this classification remains controversial. Hybridization analyses and partial PCR-based sequence data have indicated a separate origin of these two groups, whereas a recent intertranslocation analysis suggested a single origin. To clarify the evolutionary history of this species, we analysed 10 S. pastorianus strains and the S. eubayanus type strain as a likely parent by Illumina next-generation sequencing. In addition to assembling the genomes of five of the strains, we obtained information on interchromosomal translocation, ploidy, and single-nucleotide variants (SNVs). Collectively, these results indicated that the two groups of strains share S. cerevisiae haploid chromosomes. We therefore conclude that both groups of S. pastorianus strains share at least one interspecific hybridization event and originated from a common parental species and that differences in ploidy and SNVs between the groups can be explained by chromosomal deletion or loss of heterozygosity.

  6. Hybrid-Electric Aircraft TOGW Development Tool with Empirically-Based Airframe and Physics-Based Hybrid Propulsion System Component Analysis Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Hybrid-Electric distributed propulsion (HEDP) is becoming widely accepted and new tools will be required for future development. This Phase I SBIR proposal creates a...

  7. CAVE2: a hybrid reality environment for immersive simulation and information analysis

    Science.gov (United States)

    Febretti, Alessandro; Nishimoto, Arthur; Thigpen, Terrance; Talandis, Jonas; Long, Lance; Pirtle, J. D.; Peterka, Tom; Verlo, Alan; Brown, Maxine; Plepys, Dana; Sandin, Dan; Renambot, Luc; Johnson, Andrew; Leigh, Jason

    2013-03-01

    Hybrid Reality Environments represent a new kind of visualization spaces that blur the line between virtual environments and high resolution tiled display walls. This paper outlines the design and implementation of the CAVE2TM Hybrid Reality Environment. CAVE2 is the world's first near-seamless flat-panel-based, surround-screen immersive system. Unique to CAVE2 is that it will enable users to simultaneously view both 2D and 3D information, providing more flexibility for mixed media applications. CAVE2 is a cylindrical system of 24 feet in diameter and 8 feet tall, and consists of 72 near-seamless, off-axisoptimized passive stereo LCD panels, creating an approximately 320 degree panoramic environment for displaying information at 37 Megapixels (in stereoscopic 3D) or 74 Megapixels in 2D and at a horizontal visual acuity of 20/20. Custom LCD panels with shifted polarizers were built so the images in the top and bottom rows of LCDs are optimized for vertical off-center viewing- allowing viewers to come closer to the displays while minimizing ghosting. CAVE2 is designed to support multiple operating modes. In the Fully Immersive mode, the entire room can be dedicated to one virtual simulation. In 2D model, the room can operate like a traditional tiled display wall enabling users to work with large numbers of documents at the same time. In the Hybrid mode, a mixture of both 2D and 3D applications can be simultaneously supported. The ability to treat immersive work spaces in this Hybrid way has never been achieved before, and leverages the special abilities of CAVE2 to enable researchers to seamlessly interact with large collections of 2D and 3D data. To realize this hybrid ability, we merged the Scalable Adaptive Graphics Environment (SAGE) - a system for supporting 2D tiled displays, with Omegalib - a virtual reality middleware supporting OpenGL, OpenSceneGraph and Vtk applications.

  8. Gene expression profiles in squamous cell cervical carcinoma using array-based comparative genomic hybridization analysis.

    Science.gov (United States)

    Choi, Y-W; Bae, S M; Kim, Y-W; Lee, H N; Kim, Y W; Park, T C; Ro, D Y; Shin, J C; Shin, S J; Seo, J-S; Ahn, W S

    2007-01-01

    Our aim was to identify novel genomic regions of interest and provide highly dynamic range information on correlation between squamous cell cervical carcinoma and its related gene expression patterns by a genome-wide array-based comparative genomic hybridization (array-CGH). We analyzed 15 cases of cervical cancer from KangNam St Mary's Hospital of the Catholic University of Korea. Microdissection assay was performed to obtain DNA samples from paraffin-embedded cervical tissues of cancer as well as of the adjacent normal tissues. The bacterial artificial chromosome (BAC) array used in this study consisted of 1440 human BACs and the space among the clones was 2.08 Mb. All the 15 cases of cervical cancer showed the differential changes of the cervical cancer-associated genetic alterations. The analysis limit of average gains and losses was 53%. A significant positive correlation was found in 8q24.3, 1p36.32, 3q27.1, 7p21.1, 11q13.1, and 3p14.2 changes through the cervical carcinogenesis. The regions of high level of gain were 1p36.33-1p36.32, 8q24.3, 16p13.3, 1p36.33, 3q27.1, and 7p21.1. And the regions of homozygous loss were 2q12.1, 22q11.21, 3p14.2, 6q24.3, 7p15.2, and 11q25. In the high level of gain regions, GSDMDC1, RECQL4, TP73, ABCF3, ALG3, HDAC9, ESRRA, and RPS6KA4 were significantly correlated with cervical cancer. The genes encoded by frequently lost clones were PTPRG, GRM7, ZDHHC3, EXOSC7, LRP1B, and NR3C2. Therefore, array-CGH analyses showed that specific genomic alterations were maintained in cervical cancer that were critical to the malignant phenotype and may give a chance to find out possible target genes present in the gained or lost clones.

  9. Modeling and analysis of dynamic behavior of hybrid wind-diesel power plants

    Science.gov (United States)

    Garcia, Sergio Leonardo

    This thesis develops small-signal and large-signal models to investigate the dynamic performance of a hybrid wind-diesel energy system interfaced to a utility grid. The study system comprises a 3.5-MVA diesel-generator unit operating in parallel with a 750-kVA variable-speed, squirrel-cage induction generator, wind unit. The wind unit is interfaced to the power network through a back-to-back voltage-sourced converter system. The controllers of the machine-side converter regulate the mechanical torque and the shaft speed of the induction generator to obtain maximum power production under fluctuating wind-speed conditions. The controllers of the grid-side converter maintain the dc-link voltage and the ac-side converter terminal voltage within the specified limits and ensure delivery of the captured wind power to the network. The diesel-generator unit is equipped with excitation and governor systems to compensate for (i) output power changes of the wind unit due to the intermittent nature of the wind, and (ii) changes in the load demand. Based on small-signal (eigen) analyses in the MATLABRTM software environment, the controller parameters of the wind and the diesel units are selected to guarantee (i) minimization of transients due to switch over between two consecutive modes of operation, (ii) voltage/angle stability during islanded (autonomous) mode of operation, and (iii) local load requirements in terms of voltage and real/reactive power. The results obtained from time-domain simulations, in the PSCAD RTM/EMTDCRTM software environment, demonstrate that proper adjustment of the controllers of the wind and diesel units promote "ride-through" capability in the event of (i) pre-planned transitions between different modes of operation, (ii) pre-planned islanding and re-connection of the units to the power network, and (iii) short circuits, accidental islanding and subsequent re-connection attempts to the network. The developed eigen analysis tool is structured to

  10. Three-dimensional numerical analysis of hybrid heterojunction silicon wafer solar cells with heterojunction rear point contacts

    Directory of Open Access Journals (Sweden)

    Zhi Peng Ling

    2015-07-01

    Full Text Available This paper presents a three-dimensional numerical analysis of homojunction/heterojunction hybrid silicon wafer solar cells, featuring front-side full-area diffused homojunction contacts and rear-side heterojunction point contacts. Their device performance is compared with conventional full-area heterojunction solar cells as well as conventional diffused solar cells featuring locally diffused rear point contacts, for both front-emitter and rear-emitter configurations. A consistent set of simulation input parameters is obtained by calibrating the simulation program with intensity dependent lifetime measurements of the passivated regions and the contact regions of the various types of solar cells. We show that the best efficiency is obtained when a-Si:H is used for rear-side heterojunction point-contact formation. An optimization of the rear contact area fraction is required to balance between the gains in current and voltage and the loss in fill factor with shrinking rear contact area fraction. However, the corresponding optimal range for the rear-contact area fraction is found to be quite large (e.g. 20-60 % for hybrid front-emitter cells. Hybrid rear-emitter cells show a faster drop in the fill factor with decreasing rear contact area fraction compared to front-emitter cells, stemming from a higher series resistance contribution of the rear-side a-Si:H(p+ emitter compared to the rear-side a-Si:H(n+ back surface field layer. Overall, we show that hybrid silicon solar cells in a front-emitter configuration can outperform conventional heterojunction silicon solar cells as well as diffused solar cells with rear-side locally diffused point contacts.

  11. Near hybrid passenger vehicle development program, phase 1. Appendices A and B. Mission analysis and performance specification studies report, volume 1

    Science.gov (United States)

    1979-01-01

    The three most promising vehicle use patterns (missions) for the near term electric hybrid vehicle were found to be all-purpose city driving, commuting, and family and civic business. The mission selection process was based principally on an analysis of the travel patterns found in the Nationwide Transportation Survey and on the Los Angeles and Washington, D.C. origin-destination studies data. Travel patterns in turn were converted to fuel requirements for 1985 conventional and hybrid cars. By this means, the potential fuel savings for each mission were estimated, and preliminary design requirements for hybrid vehicles were derived.

  12. Hybrid Baryons

    CERN Document Server

    Page, P R

    2003-01-01

    We review the status of hybrid baryons. The only known way to study hybrids rigorously is via excited adiabatic potentials. Hybrids can be modelled by both the bag and flux-tube models. The low-lying hybrid baryon is N 1/2^+ with a mass of 1.5-1.8 GeV. Hybrid baryons can be produced in the glue-rich processes of diffractive gamma N and pi N production, Psi decays and p pbar annihilation.

  13. Research on Hybrid Vehicle Drivetrain

    Science.gov (United States)

    Xie, Zhongzhi

    Hybrid cars as a solution to energy saving, emission reduction measures, have received widespread attention. Motor drive system as an important part of the hybrid vehicles as an important object of study. Based on the hybrid electric vehicle powertrain control system for permanent magnet synchronous motor as the object of study. Can be applied to hybrid car compares the characteristics of traction motors, chose permanent magnet synchronous Motors as drive motors for hybrid vehicles. Building applications in hybrid cars in MATLAB/Simulink simulation model of permanent-magnet synchronous motor speed control system and analysis of simulation results.

  14. Development and functional analysis of novel genetic promoters using DNA shuffling, hybridization and a combination thereof.

    Directory of Open Access Journals (Sweden)

    Rajiv Ranjan

    Full Text Available BACKGROUND: Development of novel synthetic promoters with enhanced regulatory activity is of great value for a diverse range of plant biotechnology applications. METHODOLOGY: Using the Figwort mosaic virus full-length transcript promoter (F and the sub-genomic transcript promoter (FS sequences, we generated two single shuffled promoter libraries (LssF and LssFS, two multiple shuffled promoter libraries (LmsFS-F and LmsF-FS, two hybrid promoters (FuasFScp and FSuasFcp and two hybrid-shuffled promoter libraries (LhsFuasFScp and LhsFSuasFcp. Transient expression activities of approximately 50 shuffled promoter clones from each of these libraries were assayed in tobacco (Nicotiana tabacum cv. Xanthi protoplasts. It was observed that most of the shuffled promoters showed reduced activity compared to the two parent promoters (F and FS and the CaMV35S promoter. In silico studies (computer simulated analyses revealed that the reduced promoter activities of the shuffled promoters could be due to their higher helical stability. On the contrary, the hybrid promoters FuasFScp and FSuasFcp showed enhanced activities compared to F, FS and CaMV 35S in both transient and transgenic Nicotiana tabacum and Arabidopsis plants. Northern-blot and qRT-PCR data revealed a positive correlation between transcription and enzymatic activity in transgenic tobacco plants expressing hybrid promoters. Histochemical/X-gluc staining of whole transgenic seedlings/tissue-sections and fluorescence images of ImaGene Green™ treated roots and stems expressing the GUS reporter gene under the control of the FuasFScp and FSuasFcp promoters also support the above findings. Furthermore, protein extracts made from protoplasts expressing the human defensin (HNP-1 gene driven by hybrid promoters showed enhanced antibacterial activity compared to the CaMV35S promoter. SIGNIFICANCE/CONCLUSION: Both shuffled and hybrid promoters developed in the present study can be used as molecular tools to

  15. Uniform sampling analysis of a hybrid phase-locked loop with a sample-and-hold phase detector

    Science.gov (United States)

    Barab, S.; Mcbride, A. L.

    1975-01-01

    Phase-locked-loop (PLL) bit synchronizers often employ integrate-and-dump type phase detectors that provide phase error information only at discrete points in time. Usually these phase detectors are followed by sample-and-hold circuits to produce a stairstep error voltage as the input to a standard analog circuit loop filter. When the loop is configured in this manner, it is referred to as a hybrid PLL. Sampled-data analysis methods (Z transforms) are used to determine the stability and transient response of this loop.

  16. Dynamical Safety Analysis of the SABR Fusion-Fission Hybrid Reactor

    Science.gov (United States)

    Sumner, Tyler; Stacey, Weston; Ghiaassian, Seyed

    2009-11-01

    A hybrid fusion-fission reactor for the transmutation of spent nuclear fuel is being developed at Georgia Tech. The Subcritical Advanced Burner Reactor (SABR) is a 3000 MWth sodium-cooled, metal TRU-Zr fueled fast reactor driven by a tokamak fusion neutron source based on ITER physics and technology. We are investigating the accident dynamics of SABR's coupled fission, fusion and heat removal systems to explore the safety characteristics of a hybrid reactor. Possible accident scenarios such as loss of coolant mass flow (LOFA), of power (LOPA) and of heat sink (LOHSA), as well as inadvertent reactivity insertions and fusion source excursion are being analyzed using the RELAP5-3D code, the ATHENA version of which includes liquid metal coolants.

  17. Performance analysis and code recognition for dual N-ary orthogonal hybrid modulation systems

    Institute of Scientific and Technical Information of China (English)

    Qiao Xiaoqiang; Zhao Hangsheng; Cai Yueming

    2008-01-01

    A dual N-ary orthogonal hybrid modulation system is introduced in this paper, which can increase the data rate greatly compared with conventional N-ary orthogonal spread spectrum system, so it can be used for high rate data communication. Then, three code recognition algorithms are presented for dual N-ary orthogonal hybrid modulation system and the analytic bit error rate (BER) performance of the system in additive white Gaussian noise (AWGN) and flat Rayleigh fading channel is derived. Finally, the computer simulation of the system with three code recognition algorithms is performed, which shows that the simplified maximum a posteriori (MAP) algorithm is the best for the system with a compromise between the performance and the complexity.

  18. A comparative hybridization analysis of yeast DNA with Paramecium parafusin- and different phosphoglucomutase-specific probes.

    Science.gov (United States)

    Wyroba, E; Satir, B H

    2000-01-01

    Molecular probes designed for the parafusin (PFUS), the Paramecium exocytic-sensitive phosphoglycoprotein, gave distinct hybridization patterns in Saccharomyces cerevisiae genomic DNA when compared with different phosphoglucomutase specific probes. These include two probes identical to segments of yeast phosphoglucomutase (PGM) genes 1 and 2. Neither of the PGM probes revealed the 7.4 and 5.9 kb fragments in Bgl II-cut yeast DNA digest detected with the 1.6 kb cloned PFUS cDNA and oligonucleotide constructed to the PFUS region (insertion 3--I-3) not found in other species. PCR amplification with PFUS-specific primers generated yeast DNA-species of the predicted molecular size which hybridized to the I-3 probe. A search of the yeast genome database produced an unassigned nucleotide sequence that showed 55% identity to parafusin gene and 37% identity to PGM2 (the major isoform of yeast phosphoglucomutase) within the amplified region.

  19. Performance simulation and analysis of a fuel cell/battery hybrid forklift truck

    DEFF Research Database (Denmark)

    Hosseinzadeh, Elham; Rokni, Masoud; Advani, Suresh G.

    2013-01-01

    The performance of a forklift truck powered by a hybrid system consisting of a PEM fuel cell and a lead acid battery is modeled and investigated by conducting a parametric study. Various combinations of fuel cell size and battery capacity are employed in conjunction with two distinct control...... strategies to study their effect on hydrogen consumption and battery state-of-charge for two drive cycles characterized by different operating speeds and forklift loads. The results show that for all case studies, the combination of a 110 cell stack with two strings of 55 Ah batteries is the most economical...... choice for the hybrid system based on system size and hydrogen consumption. In addition, it is observed that hydrogen consumption decreases by about 24% when the maximum speed of the drive cycle is decreased from 4.5 to 3 m/s. Similarly, by decreasing the forklift load from 2.5 to 1.5 ton, the hydrogen...

  20. Design and analysis of the hybrid excitation rail eddy brake system of high-speed trains

    Institute of Scientific and Technical Information of China (English)

    Ji-en MA; Bin ZHANG; Xiao-yan HUANG; You-tong FANG; Wen-ping CAO

    2011-01-01

    Compared to the current eddy braking patterns using a single magnetic source,hybrid excitation rail eddy brakes have many advantages,such as controllability,energy saving,and various operating models.Considering the large braking power consumption of the high-speed train,a hybrid excitation rail eddy brake system,which is based on the principle of electromagnetic field,is proposed to fulfill the needs of safety and reliability.Then the working processes of the mechanical lifting system and electromagnetic system are demonstrated.With the electromagnetic system analyzed using the finite element method,the factors such as speed,air gap,and exciting current have influences on the braking force and attractive force.At last,the structure optimization of the brake system is discussed.

  1. Allergenic study and epitope analysis of Indo-American hybrid Tomatoes

    Directory of Open Access Journals (Sweden)

    Majeed Jamakhani

    2016-09-01

    Full Text Available Food allergies have high negative impact on nutritional balance of human body. Allergic response is seen high to vegetables such as tomatoes, capsicum and spinach, next to fish, eggs and nuts. Allergen molecules and epitope regions of Indo- American hybrid variety tomatoes is not well studied. The present work shows the presence of putative allergen molecules in two Indio-American hybrid tomatoes, which are identified in 7 patient sera by SDS - Immunoblotting method and further identification of epitopes, putative peptides and cross reactivity of these putative allergens by Immunoinformatics tools. Linear B-cell epitopes predicted by 3 combined immunoinformatics tools viz. DNASTAR protean, ABC pred and IEDB Bipred. Cross reactivity of these allergens determined by sequence alignment method against the allergen online database and Allermatch databases, which shows significant cross reactivity to Capsicum annum, Hevea brasiliensi, archis hypogaea, pollen, actinidia chinesis and prunus avium.

  2. Stability analysis of slot-entry hybrid journal bearings operating with non-newtonian lubricant

    Directory of Open Access Journals (Sweden)

    H.C. Garg

    2015-09-01

    Full Text Available This paper presents theoretical investigations of rheological effects of lubricant on stability parameters of various configurations of slot-entry hybrid journal bearing system. FEM has been used to solve Reynolds equation governing flow of lubricant in bearing clearance space along with restrictor flow equation using suitable iterative technique. The non-Newtonian lubricant has been assumed to follow cubic shear stress law. The stability parameters in terms of stiffness coefficients, damping coefficients, threshold speed and whirl frequency of different configurations of slot-entry hybrid journal bearing have been computed and presented for wide range of external load while operating with Newtonian and Non-Newtonian lubricants. The computed results reveal that variation of viscosity due to non-Newtonian behavior of lubricant affects bearing stability quite significantly. The results are presented in graphical form and logical conclusions are drawn to identify best possible configuration from stability point of view.

  3. A hybrid time-domain discontinuous galerkin-boundary integral method for electromagnetic scattering analysis

    KAUST Repository

    Li, Ping

    2014-05-01

    A scheme hybridizing discontinuous Galerkin time-domain (DGTD) and time-domain boundary integral (TDBI) methods for accurately analyzing transient electromagnetic scattering is proposed. Radiation condition is enforced using the numerical flux on the truncation boundary. The fields required by the flux are computed using the TDBI from equivalent currents introduced on a Huygens\\' surface enclosing the scatterer. The hybrid DGTDBI ensures that the radiation condition is mathematically exact and the resulting computation domain is as small as possible since the truncation boundary conforms to scatterer\\'s shape and is located very close to its surface. Locally truncated domains can also be defined around each disconnected scatterer additionally reducing the size of the overall computation domain. Numerical examples demonstrating the accuracy and versatility of the proposed method are presented. © 2014 IEEE.

  4. Covert Network Analysis for Key Player Detection and Event Prediction Using a Hybrid Classifier

    Directory of Open Access Journals (Sweden)

    Wasi Haider Butt

    2014-01-01

    attraction of researchers and practitioners to design systems which can detect main members which are actually responsible for such kind of events. In this paper, we present a novel method to predict key players from a covert network by applying a hybrid framework. The proposed system calculates certain centrality measures for each node in the network and then applies novel hybrid classifier for detection of key players. Our system also applies anomaly detection to predict any terrorist activity in order to help law enforcement agencies to destabilize the involved network. As a proof of concept, the proposed framework has been implemented and tested using different case studies including two publicly available datasets and one local network.

  5. Battery Sizing for Plug-in Hybrid Electric Vehicles in Beijing: A TCO Model Based Analysis

    OpenAIRE

    Cong Hou; Hewu Wang; Minggao Ouyang

    2014-01-01

    This paper proposes a total cost of ownership (TCO) model for battery sizing of plug-in hybrid electric vehicles (PHEVs). The proposed systematic TCO model innovatively integrates the Beijing driving database and optimal PHEV energy management strategies developed earlier. The TCO, including battery, fuel, electricity, and salvage costs, is calculated in yearly cash flows. The salvage cost, based on battery degradation model, is proposed for the first time. The results show that the optimal b...

  6. Performance Analysis of a Hybrid One-Sided Magnetic Exciter Mounted on a Piezoelectric Stack

    OpenAIRE

    Nandi, A.; Neogy, S.

    2010-01-01

    The present work proposes a non-contact hybrid exciter especially useful for harmonic excitation of lightly damped structures/rotors. In the proposed exciter an electromagnet is placed on a piezoelectric stack and the extension of the piezoelectric stack is made almost equal to the displacement of the structure using a simple tracking control. This largely eliminates stiffness coupling between the structure/rotor and the exciter and non-linearity in the excitation force due to the vibration o...

  7. Stability analysis for impulsive fractional hybrid systems via variational Lyapunov method

    Science.gov (United States)

    Yang, Ying; He, Yong; Wang, Yong; Wu, Min

    2017-04-01

    This paper investigates the stability properties for a class of impulsive Caputo fractional-order hybrid systems with impulse effects at fixed moments. By utilizing the variational Lyapunov method, a fractional variational comparison principle is established. Some stability and instability criteria in terms of two measures are obtained. These results generalize the known ones, extending the corresponding theory of impulsive fractional differential systems. An example is given to demonstrate their effectiveness.

  8. Performance Analysis of Wireless Mobile Radio Hybrid(DS/FH) Spread Spectrum Network

    Institute of Scientific and Technical Information of China (English)

    余晓刚; 王华; 匡镜明

    2004-01-01

    By the flexible redefinition of frequency-occupation and frequency-collision event, the frequency-collision probability of hybrid(DS/FH) spread spectrum network is analyzed. This probability is based on the simultaneous transmission number threshold and is discussed in synchronous and asynchronous circumstances respectively. And then, the network throughput based on the packet correct reception probability is analyzed. Two models which have finite and infinite population respectively is discussed. At last, the numerical results are given.

  9. Finite element analysis of hybrid energy harvesting of piezoelectric and electromagnetic

    OpenAIRE

    Muhammad Yazid Muhammad Ammar Faris; Jamil Norlida; Muhmed Razali Nik Nurul Husna; Yusoff Ahmad Razlan

    2017-01-01

    Harvesting energy from ambient vibrations is a highly required method because of the wide range of available sources that produce vibration energy application from industrial machinery to human motion application. In this paper, the implementation of harvesting energy from two technologies to form a hybrid energy harvester system was analyzed. These two technologies involve the piezoelectric harvesting energy and the electromagnetic harvesting energy. A finite element model was developed usin...

  10. Hybrid zoneless probabilistic seismic hazard analysis: Test and first application to SW Germany

    Science.gov (United States)

    Chan, C.; Gruenthal, G.

    2007-12-01

    Zoneless approaches are one option to assess probabilistic seismic hazard (PSHA). They rely simply on smoothing the epicenter locations of past events according to the fractal distribution of earthquakes in space without defining seismic source zones. However, some shortcomings are connected with these zoneless approaches. Sometimes, one cannot apply one single magnitude completeness, especially when the study area covers different catalogue areas, where different completeness patterns are valid. Furthermore, the characteristic depths of the strongest earthquakes generally differ over larger areas. With respect to these two reasons, a hybrid approach for zoneless PSHA is introduced in this study; i.e. a combination of a zoneless approach with a seismic source model based solely on the large scale geological architecture. This large scale model meets the requirements of introducing different magnitude completeness. But the probability of the earthquake occurrence is based on a pure zoneless approach. Then, instead of a time set of magnitude completeness for the entire studying area, as it is the standard procedure for zoneless approaches, various time sets for different large zones are considered. Another innovation of our approach is to take into account the actual depth of each earthquake rather than assuming a certain weighting set of depths. We apply the hybrid zoneless approach to the SW part of Germany, which represents one of the highest seismicity areas in the country. The use of area specific magnitude completeness and actual depths of all events clearly results in a more realistic PSHA. Furthermore, we compare the results of the hybrid zoneless approach with the results of a recent study using a zone-based methodology. The zone-based approach shows more significant contrasts in the study area; i.e the hybrid zoneless approach provides a rather smoothed pattern. This corresponds to comparisons between zoneless and zone-based approaches by previous studies.

  11. Total hip replacement: A meta-analysis to evaluate survival of cemented, cementless and hybrid implants

    Science.gov (United States)

    Phedy, Phedy; Ismail, H Dilogo; Hoo, Charles; Djaja, Yoshi P

    2017-01-01

    AIM To determine whether cemented, cementless, or hybrid implant was superior to the other in terms of survival rate. METHODS Systematic searches across MEDLINE, CINAHL, and Cochrane that compared cemented, cementless and hybrid total hip replacement (THR) were performed. Two independent reviewers evaluated the risk ratios of revision due to any cause, aseptic loosening, infection, and dislocation rate of each implants with a pre-determined form. The risk ratios were pooled separately for clinical trials, cohorts and registers before pooled altogether using fixed-effect model. Meta-regressions were performed to identify the source of heterogeneity. Funnel plots were analyzed. RESULTS Twenty-seven studies comprising 5 clinical trials, 9 cohorts, and 13 registers fulfilled the research criteria and analyzed. Compared to cementless THR, cemented THR have pooled RR of 0.47 (95%CI: 0.45-0.48), 0.9 (0.84-0.95), 1.29 (1.06-1.57) and 0.69 (0.6-0.79) for revision due to any reason, revision due to aseptic loosening, revision due to infection, and dislocation respectively. Compared to hybrid THR, the pooled RRs of cemented THR were 0.82 (0.76-0.89), 2.65 (1.14-6.17), 0.98 (0.7-1.38), and 0.67 (0.57-0.79) respectively. Compared to hybrid THR, cementless THR had RRs of 0.7 (0.65-0.75), 0.85 (0.49-1.5), 1.47 (0.93-2.34) and 1.13 (0.98-1.3). CONCLUSION Despite the limitations in this study, there was some tendency that cemented fixation was still superior than other types of fixation in terms of implant survival.

  12. A Hybrid Approach to Composite Damage and Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics

    Science.gov (United States)

    2017-06-30

    other provision of law. no person shall be subject to any penalty for failing to comply with a collection of Information if it does not display a ...From - To) 30-06-2017 Performance!Technical Report (Quarterl y) 04/0 I/2017 - 0613012017 4. TITLE AND SUBTITLE Sa. CONTRACT NUMBER A Hybrid Approach...ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Texas A &M Engineering Experiment Station (TEES) 400 Harvey Mitchell Parkway, Suite 300 Ml601473 I

  13. Battery Sizing for Plug-in Hybrid Electric Vehicles in Beijing: A TCO Model Based Analysis

    OpenAIRE

    Cong Hou; Hewu Wang; Minggao Ouyang

    2014-01-01

    This paper proposes a total cost of ownership (TCO) model for battery sizing of plug-in hybrid electric vehicles (PHEVs). The proposed systematic TCO model innovatively integrates the Beijing driving database and optimal PHEV energy management strategies developed earlier. The TCO, including battery, fuel, electricity, and salvage costs, is calculated in yearly cash flows. The salvage cost, based on battery degradation model, is proposed for the first time. The results show that the optimal b...

  14. Implementation of Design Failure Modes and Effects Analysis for Hybrid Vehicle Systems

    OpenAIRE

    2016-01-01

    An increase emphasis has been placed on the automotive industry to develop advanced technology vehicles which meet increasing strict government regulations and standards for emissions and fuel economy while maintaining the safety, performance, and consumer appeal of the vehicle. In response to these requirements, hybrid and electric vehicle technologies have become more complex as the necessity for vehicles with an overall better environmental impact. Modern engineers must understand the cur...

  15. Comparative analysis of pedicle screw versus hybrid instrumentation in adolescent idiopathic scoliosis surgery

    Directory of Open Access Journals (Sweden)

    Sohail Rafi

    2016-01-01

    Full Text Available Introduction: Adolescent idiopathic scoliosis is the most common type of scoliosis. A Cobb angle of 50° will progress beyond the age of spinal maturity. Surgery over bracing is advised at a Cobb angle above or equal to 50°. The aim of surgery is to bring the Cobb angle down below 50° to prevent reprogression as well as improve the quality of life. The objective of the study is to analyze the efficacy and significance in lifestyle improvement of pedicle screw-only fixation system versus the more common hybrid instrumentation system used for the surgical treatment of adolescent idiopathic scoliosis. Materials and Methods: A prospective cohort study was conducted involving two groups of patients were included in the study. One group was operated with pedicle screw-only method while the other with hybrid instrumentation system. The pre- and post-operative Cobb's angles were taken across a follow-up of 4 years. An SRS-30 questionnaire was given in a yearly follow-up to assess the lifestyle improvement of the patient. Results: Pedicle screw-only method was significantly more effective in reducing Cobb's angle (P = 0.0487. It was showed less loss of correction (P = 0.009 pedicle screw-only surgery was also better at reducing thoracic curves (P = 0.001. There seemed a better recovery time with pedicle screw surgery (P = 0.003. Conclusion: Pedicle screws are more effective and durable than hybrid systems at when treating adolescent idiopathic scoliosis.

  16. Analysis of Surface Integrity in Drilling Metal Matrix and Hybrid Metal Matrix Composites

    Institute of Scientific and Technical Information of China (English)

    T. Rajmohan; K. Palanikumar; J. Paulo Davim

    2012-01-01

    Hybrid metal matrix composites consist of at least three constituents-a metal or an alloy matrix and two reinforcements in various forms, bonded together at the atomic level in the composite. Despite their higher specific properties of strength and stiffness, the non homogeneous and anisotropic nature combined with the abrasive reinforcements render their machining difficult. In this paper, the surface integrity of machining in drilling hybrid composites has been discussed. Drilling tests are carried out at different spindle speed, feed rates, and different drill tool materials to investigate the effect of the various cutting parameters on the surface quality and the extent of the deformation of drilled surface due to drilling. Materials used for the present investigation are A1356/IOSIC (wt%) metal matrix and A1356/10SiC-3mica (wt%) hybrid composites. The composites are fabricated using stir casting route. The drilling tests are conducted on vertical computer numeric control (CNC) machining center using carbide, coated carbide and polycrystalline diamond (PCD) drills. The surface roughness decreases with increasing spindle speed and increases with increasing feed rate. The machined surface is analyzed by scanning electron microscopy (SEM). SEM images of the machined surfaces indicate the presence of grooves and pits. Microhardness depth profiles indicate that the subsurface damage is limited to the top of 100-250 μm.

  17. Analysis of mutations in oral poliovirus vaccine by hybridization with generic oligonucleotide microchips.

    Energy Technology Data Exchange (ETDEWEB)

    Proudnikov, D.; Kirillov, E.; Chumakov, K.; Donion, J.; Rezapkin, G.; Mirzabekov, A.; Biochip Technology Center; Engelhardt Inst. of Molecular Biology; Center for Biologics Evaluation and Research

    2000-01-01

    This paper describes use of a new technology of hybridization with a micro-array of immobilized oligonucleotides for detection and quantification of neurovirulent mutants in Oral Poliovirus Vaccine (OPV). We used a micro-array consisting of three-dimensional gel-elements containing all possible hexamers (total of 4096 probes). Hybridization of fluorescently labelled viral cDNA samples with such microchips resulted in a pattern of spots that was registered and quantified by a computer-linked CCD camera, so that the sequence of the original cDNA could be deduced. The method could reliably identify single point mutations, since each of them affected fluorescence intensity of 12 micro-array elements. Micro-array hybridization of DNA mixtures with varying contents of point mutants demonstrated that the method can detect as little as 10% of revertants in a population of vaccine virus. This new technology should be useful for quality control of live viral vaccines, as well as for other applications requiring identification and quantification of point mutations.

  18. Towards generating a new supernova equation of state: A systematic analysis of cold hybrid stars

    CERN Document Server

    Heinimann, Oliver; Thielemann, Friedrich-Karl

    2016-01-01

    The hadron-quark phase transition in core-collapse supernovae (CCSNe) has the potential to trigger explosions in otherwise non-exploding models. However, those hybrid supernova equations of state (EOS) shown to trigger an explosion do not support the observational 2 M_sun neutron star maximum mass constraint. In this work, we analyze cold hybrid stars by the means of a systematic parameter scan for the phase transition properties, with the aim to develop a new hybrid supernova EOS. The hadronic phase is described with the state-of-the-art supernova EOS HS(DD2), and quark matter by an EOS with a constant speed of sound ("CSS"). We find promising cases which meet the 2 M_sun criterion and are interesting for CCSN explosions. We show that the very simple CSS EOS is transferable into the well known thermodynamic bag model, important for future application in CCSN simulations. In the second part, the occurrence of reconfinement and multiple phase transitions is discussed. In the last part, the influence of hyperon...

  19. Genetic architecture of hybrid male sterility in Drosophila: analysis of intraspecies variation for interspecies isolation.

    Directory of Open Access Journals (Sweden)

    Laura K Reed

    Full Text Available BACKGROUND: The genetic basis of postzygotic isolation is a central puzzle in evolutionary biology. Evolutionary forces causing hybrid sterility or inviability act on the responsible genes while they still are polymorphic, thus we have to study these traits as they arise, before isolation is complete. METHODOLOGY/PRINCIPAL FINDINGS: Isofemale strains of D. mojavensis vary significantly in their production of sterile F(1 sons when females are crossed to D. arizonae males. We took advantage of the intraspecific polymorphism, in a novel design, to perform quantitative trait locus (QTL mapping analyses directly on F(1 hybrid male sterility itself. We found that the genetic architecture of the polymorphism for hybrid male sterility (HMS in the F(1 is complex, involving multiple QTL, epistasis, and cytoplasmic effects. CONCLUSIONS/SIGNIFICANCE: The role of extensive intraspecific polymorphism, multiple QTL, and epistatic interactions in HMS in this young species pair shows that HMS is arising as a complex trait in this system. Directional selection alone would be unlikely to maintain polymorphism at multiple loci, thus we hypothesize that directional selection is unlikely to be the only evolutionary force influencing postzygotic isolation.

  20. Neutronic analysis of a high power density hybrid reactor using innovative coolants

    Indian Academy of Sciences (India)

    Senay Yalçin; Mustafa Übeylı; Adem Acir

    2005-08-01

    In this study, neutronic investigation of a deuterium–tritium (DT) driven hybrid reactor using ceramic uranium fuels, namely UC, UO2 or UN under a high neutron wall load (NWL) of 10 MW/m2 at the first wall is conducted over a period of 24 months for fissile fuel breeding for light water reactors (LWRs). New substances, namely, Flinabe or Li20Sn80 are used as coolants in the fuel zone to facilitate heat transfer out of the blanket. Natural lithium is also utilized for comparison to these two innovative coolants. Neutron transport calculations are performed on a simple experimental hybrid blanket with cylindrical geometry with the help of the SCALE 4·3 System by solving the Boltzmann transport equation with the XSDRNPM code in 238 neutron groups and an S8-P3 approximation. The investigated blanket using Flinabe or Li20Sn80 shows better fissile fuel breeding and fuel enrichment characteristics compared to that with natural lithium which shows that these two innovative coolants can be used in hybrid reactors for higher fissile fuel breeding performance. Furthermore, using a high NWL of 10 MW/m2 at the first wall of the investigated blanket can decrease the time for fuel rods to reach the level for charging in LWRs.