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Sample records for hwang woo suk

  1. THE SOUTH KOREA'S RESEARCH ON LEGISLATIVE REGULATION OF HUMAN EGGS FOR AFTER HWANG WOO-SUK'S CASE%"黄禹锡事件"后韩国研究用人类卵子的法律规制研究

    Institute of Scientific and Technical Information of China (English)

    姬妍; 杨芳; 潘荣华

    2015-01-01

    人类卵子在医学研究领域具有独特的价值,鉴于人类卵子具有人身性和伦理性,国际社会颇为重视研究用卵子的规制. 韩国科学家黄禹锡领导的研究团队因忽视人类卵子的伦理问题,采用不正当手段收集和使用人类卵子进行科学研究,引发了举世关注的"卵子风波". 韩国以此为鉴,及时总结黄禹锡事件的教训,颁布实施《生命伦理与安全法》并多次修改,作为对黄禹锡事件的积极回应.2008年的修订稿对卵子捐赠与胚胎干细胞研究等相关内容进行完善,分析与总结韩国的法律应对经验对我国具有一定的借鉴意义.%Human eggs have unique value in the field of medical research. Owing to its personal and ethical nature, interna-tional community thinks highly of the rules and regulations of the egg for research. Ignoring the ethics of human eggs, the re-search team leaded by Korean scientist Hwang Woo-Suk collected and used human eggs for scientific research by illegal means, which caused the worldwide egg disturbance. Taking it as a mirror, South Korea learned lessons timely and enacted the Bioethics and Biosafety Act and modified repeatedly, as a positive response to Hwang's case. The revised version in 2008 per-fects relevant contents including egg donation and the research of embryonic stem cell. Analyzing and summarizing the South Korea's experience has certain significance for reference to our country.

  2. Oversight framework over oocyte procurement for somatic cell nuclear transfer: comparative analysis of the Hwang Woo Suk case under South Korean bioethics law and U.S. guidelines for human embryonic stem cell research.

    Science.gov (United States)

    Kim, Mi-Kyung

    2009-01-01

    We examine whether the current regulatory regime instituted in South Korea and the United States would have prevented Hwang's potential transgressions in oocyte procurement for somatic cell nuclear transfer, we compare the general aspects and oversight framework of the Bioethics and Biosafety Act in South Korea and the US National Academies' Guidelines for Human Embryonic Stem Cell Research, and apply the relevant provisions and recommendations to each transgression. We conclude that the Act would institute centralized oversight under governmental auspices while the Guidelines recommend politically-independent, decentralized oversight bodies including a special review body for human embryonic stem cell research at an institutional level and that the Guidelines would have provided more vigorous protection for the women who had undergone oocyte procurement for Hwang's research than the Act. We also suggest additional regulations to protect those who provide oocytes for research in South Korea.

  3. Stem-cell spin: Covering the Hwang-affair in Science and Nature

    DEFF Research Database (Denmark)

    Kjærgaard, Rikke Schmidt

    2011-01-01

    In 2006 the South Korean cloning expert Woo Suk Hwang was found guilty of fraud and scientific misconduct. The scandal was reaching far beyond Hwang’s own laboratory encompassing national pride, geopolitics and regional discussions of stem-cell research. But the HIn 2006 the South Korean cloning...... a caring and concerned South Korean research director. Science was true to this narrative over a two-year period until finally, around Christmas 2005, there was no longer any doubt about Hwang’s misbehaviour. In Nature, on the other hand, Hwang was, from the very beginning, treated with suspicion...

  4. Denotation and connotation in public representation: Semantic network analysis of Hwang supporters' internet dialogues.

    Science.gov (United States)

    Kim, Leo

    2013-04-01

    This article analyzes the internet discourses of Korean people who supported Hwang Woo Suk despite the disclosure of his scientific misconduct. During the controversial period, those who supported Hwang constructed a narrative of a fallen hero trapped by jealous rivals and an "unjust" society. The supporters' dramatized discourses compete with expert opinions of Seoul National University's Audit Board and prosecutors that investigated the scientific fraud. By introducing and applying an innovative method of semantic network analysis, this study explores how the supporters represent their personal concerns in daily life and latent social problems in South Korea, as well as the failure of science communication. In short, the supporters' internet representations connote concerns in daily life that motivated their sympathy and activism for Hwang.

  5. Stem-cell spin: Covering the Hwang-affair in Science and Nature

    DEFF Research Database (Denmark)

    Kjærgaard, Rikke Schmidt

    2011-01-01

    In 2006 the South Korean cloning expert Woo Suk Hwang was found guilty of fraud and scientific misconduct. The scandal was reaching far beyond Hwang’s own laboratory encompassing national pride, geopolitics and regional discussions of stem-cell research. But the HIn 2006 the South Korean cloning ...... the news coverage of the Hwang affair in Science and Nature demonstrates that these two leading scientific journals frame their news stories in important ways that reflect (and are reproduced by) mass media reporting....... and framed as a cynical director of a cloning factory. Media studies of science and technology tend to focus almost exclusively on how this framing process works in the mass media and ignore that this process is already well under way in scientific journals that then feed into mass media news stories. Thus...

  6. WooCommerce cookbook

    CERN Document Server

    Rauland, Patrick

    2015-01-01

    If you have ever built or managed a WordPress site and want to add e-commerce functionality into your site, WooCommerce and this book are perfect for you. Learning how to use WooCommerce through this series of recipes will give you a solid platform to add any future e-commerce needs.

  7. An interview with Hyeon-Shik Hwang

    OpenAIRE

    2016-01-01

    It gives me great pleasure to interview Dr. Hyeon-Shik Hwang, an innovative orthodontist who has developed many creative techniques over his career. Dr. Hwang was born in Korea and received his DDS and PhD degrees from Yonsei University in Seoul. He is professor and chairman of the Department of Orthodontics at Chonnam National University School of Dentistry, Gwangju, Korea. Dr. Hwang, as a faculty at the university hospital, has maintained a successful clinical practice for more than 25 year...

  8. An interview with Hyeon-Shik Hwang

    Directory of Open Access Journals (Sweden)

    Guilherme Thiesen

    2016-02-01

    Full Text Available It gives me great pleasure to interview Dr. Hyeon-Shik Hwang, an innovative orthodontist who has developed many creative techniques over his career. Dr. Hwang was born in Korea and received his DDS and PhD degrees from Yonsei University in Seoul. He is professor and chairman of the Department of Orthodontics at Chonnam National University School of Dentistry, Gwangju, Korea. Dr. Hwang, as a faculty at the university hospital, has maintained a successful clinical practice for more than 25 years. He has treated many adult patients focusing on esthetics and periodontal health and has developed many clinical techniques to improve the effectiveness and efficiency of treatment to the benefit of both the patient and practitioner. Dr. Hwang is also interested in the evaluation of facial asymmetry two- and three-dimensionally. As one of the early adopters of cone-beam volume imaging, he has given special emphasis on the management of surgical cases. He is married to Jung-Un Park with whom he has two sons. His favorite hobbies are photography and listening to music. When I was presented to him in a congress, it was a great pleasure meeting someone who I already admired for his singular work. Later on, his humbleness and knowledge made me marvel at him even more. I hope that all readers of Dental Press Journal of Orthodontics also enjoy the teachings from this brilliant Korean orthodontist! Guilherme Thiesen - interview coordinator

  9. From Hero to‘Goat'

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The spectacular fall of South Korea's best-known scientist Hwang Woo Suk for falsifying his embryonic stem cell research has shocked his own country and once again highlighted the importance of scientists' integrity and ethical standards. Hwang, 52, a professor at Seoul National University before he

  10. Twelve Elastic Constants of Betula platyphylla Suk.

    Institute of Scientific and Technical Information of China (English)

    Wang Liyu; Lu Zhenyou

    2004-01-01

    Wood elastic constants are needed to describe the elastic behaviors of wood and be taken as an important design parameter for wood-based composite materials and structural materials. This paper clarified the relationships between compliance coefficients and engineering elastic constants combined with orthotropic properties of wood, and twelve elastic constants of Betula platyphylla Suk. were measured by electrical strain gauges. Spreading the adhesive quantity cannot be excessive or too little when the strain flakes were glued. If excessive, the glue layer was too thick which would influence the strain flakes' performance, and if too little, glues plastered were not firm, which could not accurately transmit the strain. Wood as an orthotropic material, its modulus of elasticity and poisson's ratios are related by two formulas:μij /Ei =μji /Ej and μij 0.95) between the reciprocal of elastic modulus MOE-1 and the square of the ratio of depth to length (h/l)2, which indicate that shear modulus values measured were reliable by three point bending experiment.

  11. Fraud and misconduct in science: the stem cell seduction

    NARCIS (Netherlands)

    M.A.G. van der Heyden; T.D. van de Ven; T. Opthof

    2009-01-01

    Scientific misconduct and. fraud occur in science. The (anonymous) peer review process serves as goalkeeper of scientific quality rather than scientific integrity. In this brief paper we describe some limitations of the peer-review process. We describe the catastrophic facts of the 'Woo-Suk Hwang fr

  12. Kloonimiskuningas osutus tüssajaks / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2006-01-01

    Lõuna-Korea teadlane Hwang Woo-Suk astus möödunud aasta lõpus pettuses süüdistatuna tagasi Souli ülikooli professori kohalt, olles varem alusetult väitnud, et on saavutanud läbimurde geenitehnoloogias ning suudab tõhusalt tüvirakke luua

  13. WooW-II: Workshop on open workflows

    Directory of Open Access Journals (Sweden)

    Daniel Arribas-Bel

    2015-07-01

    Full Text Available This resource describes WooW-II, a two-day workshop on open workflows for quantitative social scientists. The workshop is broken down in five main parts, where each of them typically consists of an introductionary tutorial and a hands-on assignment. The specific tools discussed in this workshop are Markdown, Pandoc, Git, Github, R, and Rstudio, but the theoretical approach applies to a wider range of tools (e.g., LATEX and Python. By the end of the workshop, participants should be able to reproduce a paper of their own and make it available in an open form applying the concepts and tools introduced.

  14. Kolm Armastust ja Anarhiat. Nekrofiil, drellimõrvar ja John Woo Tallinnas / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2009-01-01

    Helsingi filmifestivali "Armastus ja Anarhia" mitme seansi toimumisest Eestis 1993.a. septembris : Abel Ferrara "Drellimõrvar" ("Driller Killer", 1979), sakslase Jörg Buttgereiti "Nekromantik" (1987) ja "Nekromantik 2" (1991), John Woo "Hard Boiled" (1993). Buttgereit ja Woo olid ka ise kohal

  15. Kolm Armastust ja Anarhiat. Nekrofiil, drellimõrvar ja John Woo Tallinnas / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-

    2009-01-01

    Helsingi filmifestivali "Armastus ja Anarhia" mitme seansi toimumisest Eestis 1993.a. septembris : Abel Ferrara "Drellimõrvar" ("Driller Killer", 1979), sakslase Jörg Buttgereiti "Nekromantik" (1987) ja "Nekromantik 2" (1991), John Woo "Hard Boiled" (1993). Buttgereit ja Woo olid ka ise kohal

  16. A New Monoterpene Glucoside from the Leaves of Betula platyphylla Suk.

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A new monoterpene glucoside, (2E,6Z)-2,6-dimethyl-8-b-D-glucosyloxy-2,6-octadien- oic acid, was isolated from the leaves of Betula platyphylla Suk. The structure was established by spectroscopic data.

  17. In vivo antimalarial activity of the endophytic actinobacteria, Streptomyces SUK 10.

    Science.gov (United States)

    Baba, Mohd Shukri; Zin, Noraziah Mohamad; Hassan, Zainal Abidin Abu; Latip, Jalifah; Pethick, Florence; Hunter, Iain S; Edrada-Ebel, RuAngelie; Herron, Paul R

    2015-12-01

    Endophytic bacteria, such as Streptomyces, have the potential to act as a source for novel bioactive molecules with medicinal properties. The present study was aimed at assessing the antimalarial activity of crude extract isolated from various strains of actinobacteria living endophytically in some Malaysian medicinal plants. Using the four day suppression test method on male ICR strain mice, compounds produced from three strains of Streptomyces (SUK8, SUK10, and SUK27) were tested in vivo against Plasmodium berghei PZZ1/100 in an antimalarial screen using crude extracts at four different concentrations. One of these extracts, isolated from Streptomyces SUK10 obtained from the bark of Shorea ovalis tree, showed inhibition of the test organism and was further tested against P. berghei-infected mice for antimalarial activity at different concentrations. There was a positive relationship between the survival of the infected mouse group treated with 50 µg/kg body weight (bw) of ethyl acetate-SUK10 crude extract and the ability to inhibit the parasites growth. The parasite inhibition percentage for this group showed that 50% of the mice survived for more than 90 days after infection with the parasite. The nucleotide sequence and phylogenetic tree suggested that Streptomyces SUK10 may constitute a new species within the Streptomyces genus. As part of the drug discovery process, these promising finding may contribute to the medicinal and pharmaceutical field for malarial treatment.

  18. Fraud and misconduct in science: the stem cell seduction: Implications for the peer-review process.

    Science.gov (United States)

    van der Heyden, M A G; van de Ven, T; Opthof, T

    2009-01-01

    Scientific misconduct and fraud occur in science. The (anonymous) peer review process serves as goalkeeper of scientific quality rather than scientific integrity. In this brief paper we describe some limitations of the peer-review process. We describe the catastrophic facts of the 'Woo-Suk Hwang fraud case' and raise some ethical concerns about the issue. Finally, we pay attention to plagiarism, autoplagiarism and double publications. (Neth Heart J 2009;17:25-9.).

  19. Genetic mapping and biochemical characterization of suppressor mutations sukA and sukB for a dnaK7(Ts) mutation of Escherichia coli K-12.

    Science.gov (United States)

    Itikawa, H; Mishina, Y; Wada, M; Fujita, H

    1992-02-01

    Temperature-resistant pseudorevertants were isolated from a dnaK7(Ts) mutant of Escherichia coli K-12. Two of these pseudorevertants were shown to carry suppressor mutations, sukA and sukB, respectively. Genetic mapping by conjugation and P1-transduction revealed that these suppressor mutations were located at two distinct sites between 76 and 77 min close to the suhA and rpoH genes. Labeled cellular proteins were extracted from suppressor mutants grown at various temperatures and subjected to SDS-gel electrophoresis. Autoradiograms of the gels indicated that these suppressor mutations each resulted in increased synthesis of the heat shock protein Lon (an ATP-dependent protease, La) at both permissive and nonpermissive temperatures.

  20. PLATYPHYLLIN A, A NOVEL COUMARONE FROM THE LEAVES OF BETULA PLATYPHYLLA SUK.

    Institute of Scientific and Technical Information of China (English)

    SU-JUAN WANG; YUE-HU PEI; HUI-MING HUA

    2001-01-01

    A novel coumarone, platyphyllin A (1), was isolated from the leaves of Betula platyphylla Suk..The structure elucidation was accomplished by the analysis of spectroscopic data. Compound 1 was identified as a new coumarone skeleton, which was first isolated from plants.

  1. Translation and validation of the Western Ontario Osteoarthritis of the Shoulder (WOOS) index – the Danish version

    DEFF Research Database (Denmark)

    Rasmussen, Jeppe V; Jakobsen, John; Olsen, Bo S;

    2013-01-01

    The Western Ontario Osteoarthritis of the Shoulder (WOOS) index is a patient-reported, disease-specific questionnaire for the measurement of the quality-of-life in patients with osteoarthritis. The purpose of this study was to describe the process used to translate the WOOS into Danish and to test...

  2. Ethical modernization: research misconduct and research ethics reforms in Korea following the Hwang affair.

    Science.gov (United States)

    Kim, Jongyoung; Park, Kibeom

    2013-06-01

    The Hwang affair, a dramatic and far reaching instance of scientific fraud, shocked the world. This collective national failure prompted various organizations in Korea, including universities, regulatory agencies, and research associations, to engage in self-criticism and research ethics reforms. This paper aims, first, to document and review research misconduct perpetrated by Hwang and members of his research team, with particular attention to the agencies that failed to regulate and then supervise Hwang's research. The paper then examines the research ethics reforms introduced in the wake of this international scandal. After reviewing American and European research governance structures and policies, policy makers developed a mixed model mindful of its Korean context. The third part of the paper examines how research ethics reform is proactive (a response to shocking scientific misconduct and ensuing external criticism from the press and society) as well as reactive (identification of and adherence to national or international ethics standards). The last part deals with Korean society's response to the Hwang affair, which had the effect of a moral atomic bomb and has led to broad ethical reform in Korean society. We conceptualize this change as ethical modernization, through which the Korean public corrects the failures of a growth-oriented economic model for social progress, and attempts to create a more trustworthy and ethical society.

  3. Justification and Persuasion about Cloning: Arguments in Hwang's Paper and Journalistic Reported Versions

    Science.gov (United States)

    Jimenez-Aleixandre, Maria Pilar; Federico-Agraso, Marta

    2009-01-01

    We examine the argumentative structure of Hwang et al.'s (2004) paper about human somatic cell nuclear transfer (SCNT, or "therapeutic cloning"), contrasted with four Journalistic Reported Versions (JRV) of it, and with students' summaries of one JRV. As the evaluation of evidence is one of the critical features of argumentation…

  4. Biodegradation and detoxification of reactive textile dye by isolated Pseudomonas sp. SUK1.

    Science.gov (United States)

    Kalyani, Dayanad C; Telke, Amar A; Govindwar, Sanjay P; Jadhav, Jyoti P

    2009-03-01

    An isolated bacterium from a textile disposal site, Pseudomonas sp. SUK1, has the ability to decolorize the reactive textile dyes and methyl orange. This bacterium showed the potential to decolorize the textile dye Reactive Blue 59 at a high concentration (5 g/L(-1)), which is frequently used in the textile industry of Solapur, India. Induction in the activities of lignin peroxidase, azoreductase, and dichlorophenol indophenol reductase was observed during the decolorization of Methyl Orange and Reactive Blue 59. Methyl Orange (as model azo dye) was used to understand the mechanism of biodegradation by Pseudomonas sp. SUK1. The final product was identified as 1,4-benzenediamine, N, N-dimethyl by gas chromatography-mass spectroscopy. Microbial and phytotoxicity studies revealed the nontoxic nature of the products of Reactive Blue 59.

  5. Korean Literature in a Situation of Division : with an emphasis on Hwang Soon-Won's Novels

    OpenAIRE

    Pak, Jae-sup

    2004-01-01

    Korean war in 1950's has great influence on Korean literature. Hwang Soon-Won's novels portray the flow of history that contains Korean war and division (South and North Korea). Disintegration of personality, psychological frigidity, and pressure from poverty, pain of family separation caused by the war are well depicted in his works. But his literary accomplishment as the novelist, is showing how the traumatic experiences caused by the Korean War can be healed through humanity, with artistic...

  6. Justification and Persuasion about Cloning: Arguments in Hwang's Paper and Journalistic Reported Versions

    Science.gov (United States)

    Jiménez-Aleixandre, María Pilar; Federico-Agraso, Marta

    2009-05-01

    We examine the argumentative structure of Hwang et al.’s (2004) paper about human somatic cell nuclear transfer (SCNT, or ‘therapeutic cloning’), contrasted with four Journalistic Reported Versions (JRV) of it, and with students’ summaries of one JRV. As the evaluation of evidence is one of the critical features of argumentation (Jiménez-Aleixandre 2008), the analysis focuses on the use of evidence, drawing from instruments to analyze written argumentation (Kelly et al. 2008) and from studies about the structure of empirical research reports (Swales 2001). The objectives are: 1) To examine the use of evidence and the argumentative structure of Hwang et al.’s Science, 303: 1669-1674 (2004) original paper in terms of the criteria: a) pertinence of the evidence presented to the claims; b) sufficiency of the evidence for the purpose of supporting the claims; and c) coordination of the evidence across epistemic levels. 2) To explore how the structure of Hwang’s paper translates into the JRV and into university students’ perceptions about the evidence supporting the claims. The argumentative structure of Hwang’s paper is such that its apparently ostensible main claim about NT constitutes a justification for a second claim about its therapeutic applications, for which no evidence is offered. However, this second claim receives prominent treatment in the JRV and in the students’ summaries. Implications for promoting critical reading in the classroom are discussed.

  7. Biodegradation of reactive textile dye Red BLI by an isolated bacterium Pseudomonas sp. SUK1.

    Science.gov (United States)

    Kalyani, D C; Patil, P S; Jadhav, J P; Govindwar, S P

    2008-07-01

    A novel bacterial strain capable of decolorizing reactive textile dye Red BLI is isolated from the soil sample collected from contaminated sites of textile industry from Solapur, India. The bacterial isolate was identified as Pseudomonas sp. SUK1 on the basis of 16S rDNA analysis. The Pseudomonas sp. SUK1 decolorized Red BLI (50 mg l(-1)) 99.28% within 1h under static anoxic condition at pH range from 6.5 to 7.0 and 30 degrees C. This strain has ability to decolorize various reactive textile dyes. UV-Vis spectroscopy, FTIR and TLC analysis of samples before and after dye decolorization in culture medium confirmed decolorization of Red BLI. A significant increase in the activities of aminopyrine N-demethylase and NADH-DCIP reductase in cells obtained after decolorization indicates involvement of these enzymes in the decolorization process. Phytotoxicity testing with the seeds of Sorghum vulgare and Phaseolus mungo, showed more sensitivity towards the dye, while the products obtained after dye decolorization does not have any inhibitory effects.

  8. Gancidin W, a potential low-toxicity antimalarial agent isolated from an endophytic Streptomyces SUK10

    Science.gov (United States)

    Zin, Noraziah Mohamad; Baba, Mohd Shukri; Zainal-Abidin, Abu Hassan; Latip, Jalifah; Mazlan, Noor Wini; Edrada-Ebel, RuAngelie

    2017-01-01

    Endophytic Streptomyces strains are potential sources for novel bioactive molecules. In this study, the diketopiperazine gancidin W (GW) was isolated from the endophytic actinobacterial genus Streptomyces, SUK10, obtained from the bark of Shorea ovalis tree, and it was tested in vivo against Plasmodium berghei PZZ1/100. GW exhibited an inhibition rate of nearly 80% at 6.25 and 3.125 μg kg−1 body weight on day four using the 4-day suppression test method on male ICR strain mice. Comparing GW at both concentrations with quinine hydrochloride and normal saline as positive and negative controls, respectively, 50% of the mice treated with 3.125 μg kg−1 body weight managed to survive for more than 11 months after infection, which almost reached the life span of normal mice. Biochemical tests of selected enzymes and proteins in blood samples of mice treated with GW were also within normal levels; in addition, no abnormalities or injuries were found on internal vital organs. These findings indicated that this isolated bioactive compound from Streptomyces SUK10 exhibits very low toxicity and is a good candidate for potential use as an antimalarial agent in an animal model. PMID:28223778

  9. Spotted hyaenas Crocuta crocuta prey on new-born elephant calves in Hwange National Park, Zimbabwe

    Directory of Open Access Journals (Sweden)

    Julia Salnicki

    2001-08-01

    Full Text Available Spotted hyaena Crocuta crocuta are known to be opportunists and to have a varied diet including mammals, reptiles and birds. Prey most often hunted are medium sized ungulates but spotted hyaenas will on occasion take larger species such as giraffe Giraffa camelopardalis and zebra Equus burchellii. They are also known to hunt whichever species are most abundant and will vary their prey seasonally. In this study spotted hyaenas were observed to take an unusual prey species in the form of elephant calves (Loxodonta africana. On a number of occasions hyaenas were observed feeding on or killing newborn and very young elephant calves. These observations were made whilst the authors were conducting research on spotted hyaena ecology in the woodlands of Hwange National Park, Zimbabwe and were made during the dry season between September and November 1999.

  10. Impact of African elephants on Baikiaea plurijuga woodland around natural and artificial watering points in northern Hwange National Park, Zimbabwe

    NARCIS (Netherlands)

    Mukwashi, K.; Gandiwa, E.; Kativu, S.

    2012-01-01

    The extent of African elephant (Loxodonta africana) induced damage on shrub and mature Baikiaea plurijuga trees was investigated around artificial and natural watering points in northern Hwange National Park, Zimbabwe. Damage was assessed in three zones of elephant occupancy during the dry season

  11. Effect of Herbal Acupuncture with Sang-hwang(Phellinus linteus on High Fat Diet-induced Obesity in Rats

    Directory of Open Access Journals (Sweden)

    Ji Hyun Kim

    2004-02-01

    Full Text Available Acupuncture has fairly good weight-reducing effect in treating simple obesity due to the neuroendocrine regulation. In this study, the anti-obesity effects of herbal acupuncture (HA with Sang-hwang (Phellinus linteus at Fuai (SP16 were investigated in the rat fed on high-fat (HF diet. Sang-hwang mushroom has been proven to have anti-carcinogenic effects and Sang-hwang extracts are highly effective in treatment and preventive treatment of AIDS, diabetes and high blood-pressure. To determine whether the Sang-hwang herbal acupuncture may have the anti-obesity effect, male Sprague-Dawley (4-wk-old rats were fed a HF diet for 5 wk, which produced significant weight gain compared to rats were fed a normal diet, and then herbal acupuncture were treated for 3 wk in HF diet group. The body weight, food consumption, food effeciency ratio (FER, body fat mass, plasma nitric oxide (NO were investigated in rats fed on normal diet, HF diet, and HF diet with HA (HF-diet-HA groups. NO has been proposed to be involved in the regulation of food intake. In addition, the expression of appetite peptides such as orexigenic peptide neuropeptide Y (NPY and the anorectic peptide cholecystokinin (CCK were observed in the hypothalamus. HF-HA group reduced body weight gain, FER, body fat contents and NO concentration compared to HF diet group. The expression of NPY was reduced in arcuate nucleus (ARC, and CCK was increased in the paraventricular nucleus (PVN after treatment of HA. In conclusion, Sang-hwang HA reduced adipocity, plasma NO and hypothalamic NPY, but increased CCK expression in the HF diet-induced obesity rat, therefore HA may have anti-obesity action through regulating body weight and appetite peptide of the central nervous system.

  12. Translation and validation of the Western Ontario Osteoarthritis of the Shoulder (WOOS index – the Danish version

    Directory of Open Access Journals (Sweden)

    Rasmussen JV

    2013-09-01

    Full Text Available Jeppe V Rasmussen,1 John Jakobsen,2 Bo S Olsen,1 Stig Brorson1 1Department of Orthopedic Surgery, Herlev University Hospital, Herlev, Denmark; 2Department of Orthopedic Surgery, Aalborg University Hospital, Thisted, Denmark Background and purpose: The Western Ontario Osteoarthritis of the Shoulder (WOOS index is a patient-reported, disease-specific questionnaire for the measurement of the quality-of-life in patients with osteoarthritis. The purpose of this study was to describe the process used to translate the WOOS into Danish and to test the translation in a Danish population, in terms of validity, reliability, and responsiveness. Material and methods: The translation of the WOOS was done according to international standardized guidelines. The psychometric properties were tested in 20 consecutive patients. The eligibility criteria were: a diagnosis of osteoarthritis without symptomatic rotator cuff pathology and treated with primary shoulder replacement. Patients were excluded only in the case of other pathology of the upper extremity or in the case of cognitive or linguistic impairment compromising the ability to complete the questionnaires. Results: The Pearson's correlation coefficient between the WOOS and the Constant-Murley score (CMS, preoperatively was 0.62 (P = 0.004 and the correlation between the changes of score for the WOOS and CMS was 0.73 (P < 0.001. The correlation coefficient between the WOOS and the CMS, SF-36, and the Oxford Shoulder Score postoperatively was 0.82 (P < 0.001, 0.48 (P = 0.03, and 0.82 (P < 0.001, respectively. There were no floor and ceiling effects. The Cronbach's alpha was 0.98. The intraclass correlation coefficient between test and retest was 0.96. The standardized response mean was 1.41, and effect size was 2.32. Conclusion: We have shown that the Danish version of the WOOS, translated according to international standardized guidelines, has substantial statistical and clinical psychometric properties at

  13. Penerapan Strategi Pemasaran Pada UMKM Melalui Metode Analisis SWOT (Studi Pada Toko Pakaian Sukli Fashion di Pasar Petisah Medan)

    OpenAIRE

    Freddy

    2016-01-01

    Each business unit aims to maintain its viability and to develop, by maintaining and increasing the profit. These objectives can be achieved through marketing, by implementing marketing strategies by analyzing the internal and external factors of the company. The research was conducted at Sukli Fashion Clothing Store. Phenomenon is the slow progress of this shop business when business efforts have been made. The purpose of this study is to analyze the internal and external factors of comp...

  14. Sedimentology, Sequence Stratigraphy and Reservoir Characterization of Samana Suk Formation Exposed in Namal Gorge Section, Salt Range, Mianwali, Punjab, Pakistan

    Directory of Open Access Journals (Sweden)

    Muhammad Hayat

    2016-06-01

    Full Text Available Samana Suk Formation of Bathonian-callovain age, exposed in Nammal Gorge Salt Range, has been studied for microfacies and sequence stratigraphic investigation. The formation is mainly composed of limestone, with minor beds of sandstone and marl. The limestone is grey, yellowish and purple in color. Limestone is fine grained, thin to medium bedded and inter-bedded with algal laminations. The sandstone is light yellowish brown, brick red in color, calcareous and quartzose. Within Samana Suk Formation one 2ndorder sequence and two 3rdorder sequences have been identified. Their regional correlation through fine-tuned dating helped to develop basin fill model and to understand facies dynamics. A facie belt comprising a wide belt of carbonate facies characterized by Peloidal Packstone microfacies represents inner ramp setting and Pelletal/ Peloidal Wackstone, Mud-Wackstone and Mudstone microfacies represent the low energy lagoonal environment. The sandstone lithofacies represents high energy beach environment which indicates aggrading to pro-grading pattern. The porosity analysis has been done on different samples of limestone and sandstone. For the porosity analysis the Image J software is used. In limestone the porosity ranges up to 6% while in sandstone the porosity ranging up to 18%. From the field and porosity analysis it is concluded that Samana Suk Formation in study area is good reservoir.

  15. Perceptions on climate change and its impact on livelihoods in Hwange district, Zimbabwe

    Directory of Open Access Journals (Sweden)

    Charles Nhemachena

    2014-03-01

    Full Text Available This study investigated perceptions of rural communities on climate change and its impacts on livelihoods. The research was conducted in the semi-arid Hwange district in Matebelel and North province of Zimbabwe. The perceptions were compared with empirical evidence from climatic studies on trends on temperature and rainfall, and impacts on livelihoods in the country and region. The findings from the current study are generally in agreement with those of other studies that indicate changes in the climate, especially in terms of rainfall. This largely applies to short-term periods; however, for long-term periods it is difficult to accurately relate rural community perceptions to changes in rainfall over time. Despite perceived changes and impacts of climate change on local livelihood activities, mainly agriculture, there are multiple stressors that the communities face which also affect their livelihoods. Further evidence-based research is required to disentangle climate change impacts on livelihoods, including livelihood impacts arising from interactions of climate and non-climatic factors.

  16. Research Misconduct—Definitions, Manifestations and Extent

    Directory of Open Access Journals (Sweden)

    Lutz Bornmann

    2013-10-01

    Full Text Available In recent years, the international scientific community has been rocked by a number of serious cases of research misconduct. In one of these, Woo Suk Hwang, a Korean stem cell researcher published two articles on research with ground-breaking results in Science in 2004 and 2005. Both articles were later revealed to be fakes. This paper provides an overview of what research misconduct is generally understood to be, its manifestations and the extent to which they are thought to exist.

  17. New scandals – time to rethink the rules?

    Directory of Open Access Journals (Sweden)

    Pietro Greco

    2006-03-01

    Full Text Available The scandal of the “biotechnology evangelist” erupted in Korea at the beginning of the new year: a commission from Seoul National University announced that it had proof that Dr Woo Suk Hwang, considered one of the world’s foremost experts on cloning by nucleus transfer, had manipulated the data concerning experiments in human cell cloning and the creation of eleven lines of stem cells from human embryos published in two different articles in the journal Science in 2004 and 2005.

  18. New scandals – time to rethink the rules? (Italian original version

    Directory of Open Access Journals (Sweden)

    Pietro Greco

    2006-03-01

    Full Text Available The scandal of the “biotechnology evangelist” erupted in Korea at the beginning of the new year: a commission from Seoul National University announced that it had proof that Dr Woo Suk Hwang, considered one of the world’s foremost experts on cloning by nucleus transfer, had manipulated the data concerning experiments in human cell cloning and the creation of eleven lines of stem cells from human embryos published in two different articles in the journal Science in 2004 and 2005.

  19. David Henry Hwang's Drama Research Review in China%国内黄哲伦戏剧研究综述

    Institute of Scientific and Technical Information of China (English)

    宋艳莉

    2015-01-01

    黄哲伦( David Henry Hwang)是美国当代著名的华裔剧作家。《蝴蝶君》一剧让他声名大噪,并确立了他在戏剧界的地位,同时他也因此剧受到了国内学者的关注。从2000年国内就开始有了关于他的研究,并且研究数量逐年增加,其中不乏一些值得重视的观点。但是笔者经总结发现,关于黄哲伦的研究主要集中于他的《蝴蝶君》上,其他作品研究相对较少,内容主要集中于对其写作主题及思想的研究。本文通过对国内这一领域的研究现状与研究特点进行考察,试图发现我国对黄哲伦研究在理论方法、研究视角与关注侧重等方面呈现出的特点,以及存在的不足并找出新的研究空间。%David Henry Hwang is a famous contemporary Chinese-American playwright whose play M. Butterfly has earned him world-wide fame and reputation in the theater. Thereafter, he is paid attention to by the domestic scholars mainly for this play. Since 2000, studies about Hwang and his works have begun and the number has been increasing gradually. However, after careful analysis, the paper finds that most of researches about Hwang are focused on M. Butterfly and only a few are concerned about his other works. In addition, the contents are about his writing themes. Therefore, this article tries to find the insufficiency in literary methods and research perspectives and new rooms about Hwang's research by analyzing the domestic research status and features.

  20. Ecofriendly biodegradation and detoxification of Reactive Red 2 textile dye by newly isolated Pseudomonas sp. SUK1

    Energy Technology Data Exchange (ETDEWEB)

    Kalyani, D.C.; Telke, A.A.; Dhanve, R.S. [Department of Biochemistry, Shivaji University, Kolhapur 416004 (India); Jadhav, J.P. [Department of Biochemistry, Shivaji University, Kolhapur 416004 (India)], E-mail: jpj_biochem@unishivaji.ac.in

    2009-04-30

    The aim of this work is to evaluate textile dyes degradation by novel bacterial strain isolated from the waste disposal sites of local textile industries. Detailed taxonomic studies identified the organisms as Pseudomonas species and designated as strain Pseudomonas sp. SUK1. The isolate was able to decolorize sulfonated azo dye (Reactive Red 2) in a wide range (up to 5 g l{sup -1}), at temperature 30 deg. C, and pH range 6.2-7.5 in static condition. This isolate also showed decolorization of the media containing a mixture of dyes. Measurements of COD were done at regular intervals to have an idea of mineralization, showing 52% reduction in the COD within 24 h. Induction in the activity of lignin peroxidase and azoreductase was observed during decolorization of Reactive Red 2 in the batch culture, which represented their role in degradation. The biodegradation was monitored by UV-vis, IR spectroscopy, HPLC. The final product, 2-naphthol was characterized by GC-mass spectroscopy. The phytotoxicity study revealed the degradation of Reactive Red 2 into non-toxic product by Pseudomonas sp. SUK1.

  1. Ecofriendly biodegradation and detoxification of Reactive Red 2 textile dye by newly isolated Pseudomonas sp. SUK1.

    Science.gov (United States)

    Kalyani, D C; Telke, A A; Dhanve, R S; Jadhav, J P

    2009-04-30

    The aim of this work is to evaluate textile dyes degradation by novel bacterial strain isolated from the waste disposal sites of local textile industries. Detailed taxonomic studies identified the organisms as Pseudomonas species and designated as strain Pseudomonas sp. SUK1. The isolate was able to decolorize sulfonated azo dye (Reactive Red 2) in a wide range (up to 5 g l(-1)), at temperature 30 degrees C, and pH range 6.2-7.5 in static condition. This isolate also showed decolorization of the media containing a mixture of dyes. Measurements of COD were done at regular intervals to have an idea of mineralization, showing 52% reduction in the COD within 24h. Induction in the activity of lignin peroxidase and azoreductase was observed during decolorization of Reactive Red 2 in the batch culture, which represented their role in degradation. The biodegradation was monitored by UV-vis, IR spectroscopy, HPLC. The final product, 2-naphthol was characterized by GC-mass spectroscopy. The phytotoxicity study revealed the degradation of Reactive Red 2 into non-toxic product by Pseudomonas sp. SUK1.

  2. Decolorization of adsorbed textile dyes by developed consortium of Pseudomonas sp. SUK1 and Aspergillus ochraceus NCIM-1146 under solid state fermentation.

    Science.gov (United States)

    Kadam, Avinash A; Telke, Amar A; Jagtap, Sujit S; Govindwar, Sanjay P

    2011-05-15

    The objective of this study was to develop consortium using Pseudomonas sp. SUK1 and Aspergillus ochraceus NCIM-1146 to decolorize adsorbed dyes from textile effluent wastewater under solid state fermentation. Among various agricultural wastes rice bran showed dye adsorption up to 90, 62 and 80% from textile dye reactive navy blue HE2R (RNB HE2R) solution, mixture of textile dyes and textile industry wastewater, respectively. Pseudomonas sp. SUK1 and A. ochraceus NCIM-1146 showed 62 and 38% decolorization of RNB HE2R adsorbed on rice bran in 24h under solid state fermentation. However, the consortium of Pseudomonas sp. SUK1 and A. ochraceus NCIM-1146 (consortium-PA) showed 80% decolorization in 24h. The consortium-PA showed effective ADMI removal ratio of adsorbed dyes from textile industry wastewater (77%), mixture of textile dyes (82%) and chemical precipitate of textile dye effluent (CPTDE) (86%). Secretion of extracellular enzymes such as laccase, azoreductase, tyrosinase and NADH-DCIP reductase and their significant induction in the presence of adsorbed dye suggests their role in the decolorization of RNB HE2R. GCMS and HPLC analysis of product suggests the different fates of biodegradation of RNB HE2R when used Pseudomonas sp. SUK1, A. ochraceus NCIM-1146 and consortium PA.

  3. Elektroninio parašo panaudojimo verslo įmonėse modelio sukūrimas

    OpenAIRE

    Daugėlienė, Giedrė

    2012-01-01

    Magistro baigiamajame darbe „Elektroninio parašo panaudojimo verslo įmonėse modelio sukūrimas“ išanalizuota el. parašo naudojimo problematika, el. parašo bei el. dokumentų klasifikacinės sistemos bei parengtas el. parašo taikymo versle modelis, kuris patikrintas empiriniu tyrimu. Pirmoje darbo dalyje išanalizuota el. dokumentų raida ir jų klasifikacinės sistemos. Antrajame skyriuje atlikta el. parašo taikymo verslo įmonėse sisteminė analizė: apibrėžiama el. parašo sąvoka, rūšys, el. parašo p...

  4. Comment on "Charged impurity scattering limited low temperature resistivity of low density silicon inversion layers" (Das Sarma and Hwang, cond-mat/9812216)

    OpenAIRE

    Kravchenko, S. V.; Simonian, D.; Sarachik, M. P.

    1998-01-01

    In a recent preprint cond-mat/9812216, Das Sarma and Hwang propose an explanation of the sharp decrease in resistivity at low temperatures which has been attributed to a transition to an unexpected conducting phase in dilute high-mobility two-dimensional systems at B=0. In this Comment, we examine whether their model is supported by the available experimental data.

  5. Isolation and characterization of cyclo-(tryptophanyl-prolyl) and chloramphenicol from Streptomyces sp. SUK 25 with antimethicillin-resistant Staphylococcus aureus activity

    Science.gov (United States)

    Alshaibani, Muhanna M; Jalil, Juriyati; Sidik, Nik M; Edrada-Ebel, Ruangelie; Zin, Noraziah M

    2016-01-01

    Background Zingiber spectabile, commonly known as Beehive Ginger, is used as an ethnobotanical plant in many countries as an appetizer or to treat stomachache, toothache, muscle sprain, and as a cure for swelling, sores and cuts. This is the first report of isolation of Streptomyces strain from the root of this plant. Strain Universiti Kebangsaan 25 (SUK 25) has a very high activity to produce secondary metabolites against methicillin-resistant Staphylococcus aureus (MRSA), which is associated with high morbidity and mortality rates due to acquired multidrug resistance genes and causes medication failure in some clinical cases worldwide. Phylogenetic analysis based on the 16S ribosomal RNA gene sequence exhibited that the most closely related strain was Streptomyces omiyaensis NBRC 13449T (99.0% similarity). Aim This study was conducted to carry out the extraction, identification, and biological evaluation of active metabolites isolated from SUK 25 against three MRSA strains, namely, MRSA ATCC 43300, MRSA ATCC 33591, and MRSA ATCC 49476. Materials and methods The production of secondary metabolites by this strain was optimized through Thronton’s media. Isolation, purification, and identification of the bioactive compounds were carried out using reversed-phase high-performance liquid chromatography, high-resolution mass spectrometry, Fourier transform infrared, and one-dimensional and two-dimensional nuclear magnetic resonance. Results During screening procedure, SUK 25 exhibited good antimicrobial potential against several strains of MRSA. The best biological activity was shown from fraction number VII and its subfractions F2 and F3 with minimum inhibitory concentration values at 16 µg/mL and 8 µg/mL, respectively. These two subfractions were identified as diketopiperazine cyclo-(tryptophanyl-prolyl) and chloramphenicol. Conclusion On the basis of obtained results, SUK 25 isolated from Z. spectabile can be regarded as a new valuable source to produce secondary

  6. Isolation and characterization of cyclo-(tryptophanyl-prolyl and chloramphenicol from Streptomyces sp. SUK 25 with antimethicillin-resistant Staphylococcus aureus activity

    Directory of Open Access Journals (Sweden)

    Alshaibani MM

    2016-05-01

    Full Text Available Muhanna M Alshaibani,1 Juriyati Jalil,2 Nik M Sidik,3 Ruangelie Edrada-Ebel,4 Noraziah M Zin1 1Programme of Biomedical Science, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, 2Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, 3School of Bioscience and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Malaysia; 4Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland Background: Zingiber spectabile, commonly known as Beehive Ginger, is used as an ethnobotanical plant in many countries as an appetizer or to treat stomachache, toothache, muscle sprain, and as a cure for swelling, sores and cuts. This is the first report of isolation of Streptomyces strain from the root of this plant. Strain Universiti Kebangsaan 25 (SUK 25 has a very high activity to produce secondary metabolites against methicillin-resistant Staphylococcus aureus (MRSA, which is associated with high morbidity and mortality rates due to acquired multidrug resistance genes and causes medication failure in some clinical cases worldwide. Phylogenetic analysis based on the 16S ribosomal RNA gene sequence exhibited that the most closely related strain was Streptomyces omiyaensis NBRC 13449T (99.0% similarity. Aim: This study was conducted to carry out the extraction, identification, and biological evaluation of active metabolites isolated from SUK 25 against three MRSA strains, namely, MRSA ATCC 43300, MRSA ATCC 33591, and MRSA ATCC 49476. Materials and methods: The production of secondary metabolites by this strain was optimized through Thronton’s media. Isolation, purification, and identification of the bioactive compounds were carried out using reversed-phase high-performance liquid chromatography, high-resolution mass spectrometry, Fourier transform infrared, and one-dimensional and two-dimensional nuclear magnetic

  7. Optimization of CMCase production from sorghum straw by Aspergillus terreus SUK-1 under solid substrate fermentation using response surface methodology

    Science.gov (United States)

    Tibin, El Mubarak Musa; Al-Shorgani, Najeeb Kaid Naseer; Abuelhassan, Nawal Noureldaim; Hamid, Aidil Abdul; Kalil, Mohd Sahaid; Yusoff, Wan Mohtar Wan

    2013-11-01

    The cellulase production using sorghum straw as substrate by fungal culture of Aspergillus terreus SUK-1 was investigated in solid substrate fermentation (SSF). The optimum CMCase was achieved by testing most effective fermentation parameters which were: incubation temperature, pH and moisture content using Response Surface Methodology (RSM) based on Central Composite Design (CCD). The carboxymethyl cellulase activity (CMCase) was measured as the defining factor. The results were analysed by analysis of variance (ANOVA) and the regression quadratic model was obtained. The model was found to be significant (p<0.05) and the effect of temperature (25-40°C) and pH (4-7) was found to be not significant on CMCase activity whereas the moisture content was significant in the SSF conditions employed. The high yield of predicted CMCase activity (0.2 U/ml) was obtained under the optimized conditions (temperature 40 □C, pH 5.4 and moisture content of 80%). The model was validated by applying the optimized conditions and it was found that the model was valid.

  8. Reclassification of Halomonas caseinilytica Wu et al. 2008 as a later synonym of Halomonas sinaiensis-Comments on the proposal by Hwang et al., Antonie van Leeuwenhoek 109:1345-1352, 2016.

    Science.gov (United States)

    Oren, Aharon

    2017-01-01

    Hwang et al. (Antonie van Leeuwenhoek 109:1345-1352, 2016) proposed the reclassification of Halomonas caseinilytica (Wu et al. 2008) as a later synonym of Halomonas sinaiensis, based on the publication of the latter name in 2007 by Romano et al. However, the name H. sinaiensis was validly published only in 2011. Therefore the proposal by Hwang et al. is not appropriate; instead, the name H. sinaiensis can be proposed as a later synonym of H. casinilytica.

  9. Degradation of Textile Dye Reactive Navy – Blue Rx (Reactive blue–59 by an Isolated Actinomycete Streptomyces krainskii SUK – 5

    Directory of Open Access Journals (Sweden)

    Mane, U. V.

    2008-01-01

    Full Text Available The isolated Actinomycete, Streptomyces krainskii, SUK -5 was found to decolorize and degrade textile dye Reactive blue–59.This azo dye was decolorized and degraded completely by Streptomyces krainskii SUK–5 at 24 h in shaking condition in the nutrient medium at pH 8. Induction in the activity of Lignin Peroxidase,and NADH-DCIP Reductase and MR reductase represents their role in degradation .The biodegradation was monitored by TLC, UV vis spectroscopy, FTIR. and GCMS analysis. Microbial and phytotoxicity studies of the product were carried out.

  10. Four novel cellulose synthase (CESA) genes from Birch (Betula platyphylla Suk.) involved in primary and secondary cell Wall biosynthesis.

    Science.gov (United States)

    Liu, Xuemei; Wang, Qiuyu; Chen, Pengfei; Song, Funan; Guan, Minxiao; Jin, Lihua; Wang, Yucheng; Yang, Chuanping

    2012-09-25

    Cellulose synthase (CESA), which is an essential catalyst for the generation of plant cell wall biomass, is mainly encoded by the CesA gene family that contains ten or more members. In this study; four full-length cDNAs encoding CESA were isolated from Betula platyphylla Suk., which is an important timber species, using RT-PCR combined with the RACE method and were named as BplCesA3, -4, -7 and -8. These deduced CESAs contained the same typical domains and regions as their Arabidopsis homologs. The cDNA lengths differed among these four genes, as did the locations of the various protein domains inferred from the deduced amino acid sequences, which shared amino acid sequence identities ranging from only 63.8% to 70.5%. Real-time RT-PCR showed that all four BplCesAs were expressed at different levels in diverse tissues. Results indicated that BplCESA8 might be involved in secondary cell wall biosynthesis and floral development. BplCESA3 appeared in a unique expression pattern and was possibly involved in primary cell wall biosynthesis and seed development; it might also be related to the homogalacturonan synthesis. BplCESA7 and BplCESA4 may be related to the formation of a cellulose synthase complex and participate mainly in secondary cell wall biosynthesis. The extremely low expression abundance of the four BplCESAs in mature pollen suggested very little involvement of them in mature pollen formation in Betula. The distinct expression pattern of the four BplCesAs suggested they might participate in developments of various tissues and that they are possibly controlled by distinct mechanisms in Betula.

  11. Wall Street Comes Wooing.

    Science.gov (United States)

    Stamps, David

    1997-01-01

    Lifelong learning and information technology have begun to generate investment in training businesses, raising concerns about responsiveness to customer needs, consolidation, and the future of in-house training departments. (JOW)

  12. An Ecological Paradox: The African Wild Dog (Lycaon Pictus Is Not Attracted to Water Points When Water Is Scarce in Hwange National Park, Zimbabwe.

    Directory of Open Access Journals (Sweden)

    Henry Ndaimani

    Full Text Available In dry biomes, spatio-temporal variation in surface water resource stocks is pervasive, with unknown effects on the ranging behaviour of large predators. This study assessed the effect of spatial variation in surface water resources on the ranging behaviour of the African wild dog (Lycaon pictus. We analyzed data for 1992 (dry year with 20 water points and 2000 (wet year with 30 water points against presence-only data for five packs of L. pictus in a part of Hwange National Park and adjacent smallholder communal farming areas in western Zimbabwe. Modelling the potential habitat for L. pictus using Maxent with distance from water points (Dw and Normalized Difference Vegetation Index (NDVI as predictor variables was successful for 2000 (AUC = 0.793 but not successful for 1992 (AUC = 0.423, with L. pictus probability of occurrence near water points being more for year 2000 than for year 1992. The predicted L. pictus range was wider in 1992 (~13888.1 km2 than in 2000 (~958.4 km2 (Test of Proportions, χ2 = 124.52, df = 1, P = 0.00. Using the 2nd order Multitype Nearest Neighbour Distance Function (Gcross, we also observed significant attraction between L. pictus and water points within only ~1km radius for 1992 but up to ~8km radius for 2000. Our study reinforced the notion that surface water resources attract wild dogs in the savannahs but paradoxically less so when water resources are scarce. In particular, our study furthers current understanding of the effects of changing water availability regimes on the endangered L. pictus, providing evidence that the endangered predator's home range encroaches into potential ecological traps (i.e., smallholder communal farming areas when water resources are scarce.

  13. Process and formulation variables of pregabalin microspheres prepared by w/o/o double emulsion solvent diffusion method and their clinical application by animal modeling studies.

    Science.gov (United States)

    Aydogan, Ebru; Comoglu, Tansel; Pehlivanoglu, Bilge; Dogan, Murat; Comoglu, Selcuk; Dogan, Aysegul; Basci, Nursabah

    2015-01-01

    Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults. In conventional therapy recommended dose for pregabalin is 75 mg twice daily or 50 mg three times a day, with maximum dosage of 600 mg/d. To achieve maximum therapeutic effect with a low risk of adverse effects and to reduce often drug dosing, modified release preparations; such as microspheres might be helpful. However, most of the microencapsulation techniques have been used for lipophilic drugs, since hydrophilic drugs like pregabalin, showed low-loading efficiency and rapid dissolution of compounds into the aqueous continous phase. The purpose of this study was to improve loading efficiency of a water-soluble drug and modulate release profiles, and to test the efficiency of the prepared microspheres with the help of animal modeling studies. Pregabalin is a water soluble drug, and it was encapsulated within anionic acrylic resin (Eudragit S 100) microspheres by water in oil in oil (w/o/o) double emulsion solvent diffusion method. Dichloromethane and corn oil were chosen primary and secondary oil phases, respectively. The presence of internal water phase was necessary to form stable emulsion droplets and it accelerated the hardening of microspheres. Tween 80 and Span 80 were used as surfactants to stabilize the water and corn oil phases, respectively. The optimum concentration of Tween 80 was 0.25% (v/v) and Span 80 was 0.02% (v/v). The volume of the continous phase was affected the size of the microspheres. As the volume of the continous phase increased, the size of microspheres decreased. All microsphere formulations were evaluated with the help of in vitro characterization parameters. Microsphere formulations (P1-P5) exhibited entrapment efficiency ranged between 57.00 ± 0.72 and 69.70 ± 0.49%; yield ranged between 80.95 ± 1.21 and 93.05 ± 1.42%; and mean particle size were

  14. Control of grain protein contents through SEMIDWARF1 mutant alleles: sd1 increases the grain protein content in Dee-geo-woo-gen but not in Reimei.

    Science.gov (United States)

    Terao, Tomio; Hirose, Tatsuro

    2015-06-01

    A new possibility for genetic control of the protein content of rice grains was suggested by the allele differences of the SEMIDWARF1 (SD1) mutation. Two quantitative trait loci-qPROT1 and qPROT12-were found on chromosomes 1 and 12, respectively, using backcrossed inbred lines of Sasanishiki/Habataki//Sasanishiki///Sasanishiki. One of them, qPROT1, increased almost all grain proteins instead of only certain proteins in the recessive Habataki allele. Fine mapping of qPROT1 revealed that two gene candidates-Os01g0883800 and Os01g0883900-were included in this region. Os01g0883800 encoded Gibberellin 20 oxidase 2 as well as SD1, the dwarf gene used in the so-called 'Green Revolution'. Mutant analyses as well as sequencing analysis using the semi-dwarf mutant cultivars Dee-geo-woo-gen and Calrose 76 revealed that the sd1 mutant showed significantly higher grain protein contents than their corresponding wild-type cultivars, strongly suggesting that the high protein contents were caused by sd1 mutation. However, the sd1 mutant Reimei did not have high grain protein contents. It is possible to control the grain protein content and column length separately by selecting for sd1 alleles. From this finding, the genetic control of grain protein content, as well as the column length of rice cultivars, might be possible. This ability might be useful to improve rice nutrition, particularly in areas where the introduction of semi-dwarf cultivars is not advanced.

  15. Ectomycorrhizal Formation in Seedlings of B. platyphylla Suk.%白桦幼苗外生菌根的初步研究

    Institute of Scientific and Technical Information of China (English)

    李桂兰; 麻德业

    2002-01-01

    在温室花盆中播种白桦(B.platyphytla Suk.)种子获得白桦幼苗,并对幼苗接种外生茵根真菌进行菌根合成试验.所用的外生茵根真菌有:灵芝(Ganoderma lucidum Karat)、铆钉菇(Gomphidius viscidus)、厚环乳牛肝茵(Suillusgrevillei)、褐环乳牛肝茵(S.luteus)、彩色豆马勃(Pisolithus tinctorius)、美味牛肝茵(Boletusedulis)、赭丝膜茵(Cortinarius russus)、土生空团茵(Cenococcum geophilum).接种两个月后,在灵芝、铆钉菇、厚环乳牛肝茵、褐环乳牛肝茵、彩色马勃和美味牛肝茵接种的白桦幼苗上观察到了外生茵根,而赭丝膜茵和土生空团茵接种的白桦幼苗上未形成外生茵根.进一步对形成的外生茵根做组织切片观察,在细根皮层细胞间均形成明显的哈蒂氏网,证实了6种外生茵根真茵与白桦幼苗的共生关系.

  16. The first korean doctor of medicine in ophthalmology: early career of Kong pyung woo (1907-1995) as an unusual example of medical profession in colonial Korea.

    Science.gov (United States)

    Kim, Tae-Ho

    2013-12-01

    This article traces early career of Kong Pyung Woo, a public figure famous for being the first doctor of medicine in ophthalmology with Korean ethnicity in 1936, for founding and running the oldest and still the most successful private eye clinic in Korea since 1937, and also for his engagement in development of Korean mechanical typewriter since 1949. His case is an illustrative example of how a Korean under the Japanese colonial rule (1910-1945) could build up a career to become a medical doctor, taking full advantage of the chances available. Kong, born in 1907 in a rural province in northwestern Korea, acquired a doctor's license in 1926 by passing the qualifying examination of the Government General in Korea. The qualification test was in itself an outcome of colonial education system, in which the supply of medical doctors by only a few tertiary schools could not meet the demands. After working for a state hospital for one year, Kong volunteered to be a visiting student at Keijo Medical College, to fulfill his dream of "becoming a prominent bacteriologist like Noguchi Hideyo." He was soon officially appointed as a tutor at Department of Ophthalmology, as he had been endorsed by professor Satake Shyuichi for his diligence and earnestness. Satake also encouraged Kong to pursue a doctoral degree and recommended him to Tokumitsu Yoshitomi, a professor in the Department of Pathology at Keijo Imperial University, so that Kong could experience cutting-edge research at the imperial university. Kong reported on his experiments on the pathology of chorioretinitis centralis by 1935. He submitted the reports to Nagoya Imperial University, Japan, as a doctoral thesis, and eventually obtained the degree in 1936, which was the first Korean doctor of medicine in ophthalmology. The doctorate made Kong a public figure and he opened his own private clinic in 1937. The Kong Eye Clinic was the first private eye clinic owned and run by Korean, and soon became popular in Seoul

  17. [Fraudulent publication in medical journals].

    Science.gov (United States)

    Becerril-Ángeles, Martín; García-Gómez, Francisco

    2014-01-01

    Fraud can be present in some scientific medical publications; however, the magnitude of this situation is unknown. One of the associated factors for this transgression of the good practice of investigation is the need to publish and obtain recognition and benefits, regardless of the means. The deliberate fabrication and falsification of data, plagiarism and duplication of publications are some of the scientific misconducts. Many cases of fraud in publications are known, and they have reached public opinion and have been a matter of legal sanctions (the names of Woo Suk Hwang, Jon Sudbo, Joachim Blodt, Robert Slutsky, and William Summerlin reminds us a few known cases). In the last decades, national and international regulatory organisms have been created in order to intervene against this scientific misconduct. Currently, we can rely on several effective software programs, whose function is to detect plagiarism and falsification of data. The prevention of scientific misconduct through information and education of the investigators could lead to the decrease of the presence of this problem, which damages scientific credibility and put at risk the patient's safety.

  18. Linear Collider partners woo newly opened India

    CERN Multimedia

    Bagla, Pallava

    2006-01-01

    "With the wheels of Air Force One barely off the tarmac following U.S. President George W. Bush's visit, which ended India's 3 decades as a nuclear pariah state, a delegation of U.S. and European physicists arrived here last week to discuss India's involvement in the International Linear Collider."

  19. Wooing the Chinese Car-Buyer

    Institute of Scientific and Technical Information of China (English)

    MATTHEW PLOWRIGHT; CHRISTINE TSANG

    2008-01-01

    @@ Zhu Ce is a 22-year old salesman at Beijing's largest car market, North Asia Car Market, or Beiya Cheshi (北亚车市). He has been working there a few months, and on average makes about IO sales a month. But Zhu knows next to nothing about cars. He doesn't own one himself, and his employers simply provided him with a small information pamphlet by way of training.

  20. Four Novel Cellulose Synthase (CESA Genes from Birch (Betula platyphylla Suk. Involved in Primary and Secondary Cell Wall Biosynthesis

    Directory of Open Access Journals (Sweden)

    Xuemei Liu

    2012-09-01

    Full Text Available Cellulose synthase (CESA, which is an essential catalyst for the generation of plant cell wall biomass, is mainly encoded by the CesA gene family that contains ten or more members. In this study; four full-length cDNAs encoding CESA were isolated from Betula platyphylla Suk., which is an important timber species, using RT-PCR combined with the RACE method and were named as BplCesA3, −4, −7 and −8. These deduced CESAs contained the same typical domains and regions as their Arabidopsis homologs. The cDNA lengths differed among these four genes, as did the locations of the various protein domains inferred from the deduced amino acid sequences, which shared amino acid sequence identities ranging from only 63.8% to 70.5%. Real-time RT-PCR showed that all four BplCesAs were expressed at different levels in diverse tissues. Results indicated that BplCESA8 might be involved in secondary cell wall biosynthesis and floral development. BplCESA3 appeared in a unique expression pattern and was possibly involved in primary cell wall biosynthesis and seed development; it might also be related to the homogalacturonan synthesis. BplCESA7 and BplCESA4 may be related to the formation of a cellulose synthase complex and participate mainly in secondary cell wall biosynthesis. The extremely low expression abundance of the four BplCESAs in mature pollen suggested very little involvement of them in mature pollen formation in Betula. The distinct expression pattern of the four BplCesAs suggested they might participate in developments of various tissues and that they are possibly controlled by distinct mechanisms in Betula.

  1. The Effect of Hominis Placenta Herbal Acupuncture on Bell's palsy

    OpenAIRE

    2000-01-01

    This report was done to observe the effect of Hominis placenta herbal acupuncture on Bell's palsy. The study group comprised 16 patients who arrived at Woo-suk university oriental hospital from January, 1999 till January, 2000 for Bell's palsy. All patients were divided into two group. One was herbal acupunture group, and the other was control group. Acupunture group was done herbal acupuncture therapy on the facial acupuncture points. Followings are achievement and a term of each group. I...

  2. Analysis on diameter structure of the mixed forest of Larix principis-rupprechtii Mayr.and Betula platyphylla Suk.in Mengluan Forestry Farm%河北省孟滦林场落叶松白桦混交林直径结构分析

    Institute of Scientific and Technical Information of China (English)

    崔丽红; 兰永生; 王丽华; 陈永军; 黄选瑞

    2012-01-01

    Stand diameter structure, as the most basic and important stand structure, means the distribution status of all kinds of trees with different diameters in a stand. The knowledge of the stand diameter structure is to clearly understand the results from single wood growth and stand competition. The research on the rules of dynamic changes of stand diameter structure will contribute more benefits to revealing the essence of stand development rule. The article investigates all the plants with>3 cm DBH in the mixed forest of Larix Principis-rupprechtii Mayr. and Betula platyphylla Suk. in the Mengluan Forestry Farm, Mulan Forestry Administration as research object by using sample plot method, and analyzes the distribution characteristics of diameter structure of main tree species with the statistical software Forstat2. 1. The statistic analysis shows the largest number of trees appears in the middle diameter class and the smaller number of trees in the small diameter class, with poor stand regeneration. Based on the integrated effect of normal distribution, gamma distribution, logarithmic normal distribution, binomial distribution and Poisson distribution, the forest diameter distribution law is supposed to be better reflected.%林分直径结构是林分内各种大小直径林木的分配状态,它是最基本也最重要的林分结构.了解林分的直径结构,也就对单木生长以及林分竞争所产生的结果有了清楚的认识;探讨林分直径结构动态变化规律更是有利于揭示林分发展规律的实质[1].本研究以木兰林管局孟滦林场华北落叶松白桦混交林为研究对象,采用标准地调查法对林内胸径大于3 cm的林木进行每木检尺,并使用Forstat2.1统计软件对主要树种直径结构分布规律进行研究,研究发现,各树种处于中间径阶的林木株数最多;小径阶林木较少,林分更新较差;综观拟合效果,正态分布、伽玛分布、对数正态分布、二项分布以

  3. Reproductive strategies and seeds behavior of Betula platyphylla Suk. population

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    By the methods of morphological anatomy and investigation in the sample fields, the main studies were carried out such as morphological anatomy of reproductive organs, birch population's reproductive ages, reproductive allotment value and seed behavior. The relationship between birch population and their surroundings was studied. The results showed that birch's flower organs and its seeds were suitable well for spreading by wind. The seeds by wind can fly far away in a short time. The quantity of seed spreading greatly varied with different communities. Birch's reproduction age can be changed in different ecological surroundings. The reproductive allotment value of birch was obviously different at different reproductive stages. In the mesic habitat, birch can grow well. The lowest reproductive age of them was 12, average age 15. In most cases the age of branches to bearing fruits was more than 18. The order of reproductive allotment values was as follows: a flowering phase > flower bud phase > fruit phase.

  4. Expression of bgt gene in transgenic birch (Betula platyphylla Suk.)

    African Journals Online (AJOL)

    STORAGESEVER

    2009-08-04

    Aug 4, 2009 ... dispar was verified in feeding bioassays with the insects. ... After the hybridization of the bgt probe, membranes were stripped twice for 15 min ... Southern blot analysis of transgenic birch plant DNA digested with PstI. Lane 1 ...

  5. Eyes wide open: reader and author responsibility in understanding the limits of peer review.

    Science.gov (United States)

    Benson, P J

    2015-10-01

    'Medical science can only flourish in a free society and dies under totalitarian repression.' (1) Peer review post-publication is relatively easy to define: when the world decides the importance of publication. Peer review pre-publication is what the scientific community frequently means when using the term 'peer review'. But what it is it? Few will agree on an exact definition; generally speaking, it refers to an independent, third party scrutiny of a manuscript by scientific experts (called peers) who advise on its suitability for publication. Peer review is expensive; although reviewers are unpaid, the cost in time is enormous and it is slow. There is often little agreement among reviewers about whether an article should be published and peer review can be a lottery. Often referred to as a quality assurance process, there are many examples of when peer review failed. Many will be aware of Woo-Suk Hwang's shocking stem cell research misconduct at Seoul National University. (2) Science famously published two breakthrough articles that were found subsequently to be completely fabricated and this happened in spite of peer review. Science is not unique in making this error. However, love it or hate it, peer review, for the present time at least, is here to stay. In this article, Philippa Benson, Managing Editor of Science Advances (the first open access journal of the American Association for the Advancement of Science), discusses the merits of peer review. Dr Benson has extensive experience in the publishing world and was Executive Director of PJB Consulting, a not-for-profit organisation supporting clients on issues related to converting to full electronic publishing workflows as well as challenges working with international authors and publishers. Her clients included the Public Library of Science journals, the American Society for Nutrition and the de Beaumont Foundation. She recently co-authored a book, What Editors Want: An Author's Guide to Scientific Journal

  6. The effect of clove-based herbal mouthwash on radiation-induced oral mucositis in patients with head and neck cancer: a single-blind randomized preliminary study

    OpenAIRE

    2016-01-01

    Moonkyoo Kong,1 Deok-Sang Hwang,2 Seong Woo Yoon,3 Jinsung Kim4 1Department of Radiation Oncology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, 2Department of Korean Medicine Obstetrics & Gynecology, Kyung Hee University Medical Center, 3Department of Korean Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong, 4Department of Korean Internal Medicine, Kyung Hee University Medical Center, College of Korean Medicin...

  7. Insights for integrated conservation from attitudes of people toward protected areas near Hwange National Park, Zimbabwe.

    Science.gov (United States)

    Guerbois, Chloe; Dufour, Anne-Beatrice; Mtare, Godfrey; Fritz, Herve

    2013-08-01

    Increase in human settlements at the edge of protected areas (PAs) is perceived as a major threat to conservation of biodiversity. Although it is crucial to integrate the interests of surrounding communities into PA management, key drivers of changes in local populations and the effects of conservation on local livelihoods and perceptions remain poorly understood. We assessed population changes from 1990 to 2010 in 9 villages located between 2 PAs with different management policies (access to natural resources or not). We conducted semi-directive interviews at the household level (n =217) to document reasons for settlement in the area and villager's attitudes toward the PAs. We examined drivers of these attitudes relative to household typology, feelings about conservation, and concerns for the future with mixed linear models. Population increased by 61% from 2000 to 2010, a period of political and economic crisis in Zimbabwe. Forty-seven percent of immigrants were attracted by the area; others had been resettled from other villages or were returning to family lands. Attitudes toward PAs were generally positive, but immigrants attracted by the area and who used resources within the PA with fewer restrictions expressed more negative attitudes toward PAs. Household location, losses due to wild animals, and restrictions on access to natural resources were the main drivers of this negative attitude. Profit-seeking migrants did not expect these constraints and were particularly concerned with local overpopulation and access to natural resources. To avoid socio-ecological traps near PAs (i.e., unforeseen reduced adaptive capacity) integrated conservation should address mismatches between management policy and local expectations. This requires accounting for endogenous processes, for example, local socio-ecological dynamics and values that shape the coexistence between humans and wildlife. © 2013 Society for Conservation Biology.

  8. Case Western Reserve U. Builds Virtual Campus to Woo Prospective Students

    Science.gov (United States)

    Young, Jeffrey R.

    2007-01-01

    This article describes a virtual world program that Case Western University administrators built using Second Life. It is designed for use by prospective students, who can tour the campus online. The program shows campus buildings, athletic facilities, a diner, and a virtual dormitory with window views of the athletics fields, a feature of the…

  9. Listening to Hyun-woo: What Can We Learn from a Korean American English Learner?

    Science.gov (United States)

    Han, Keonghee Tao; Scull, W. Reed

    2012-01-01

    English learners (ELs) from Confucian heritage culture (CHC) are often perceived to be reserved and conforming to the authority of the classroom. But a careful look at struggles between a CHC student and the mainstream teacher reveals that the teacher's views and pedagogical approaches shape academic and social hierarchy in the classroom.…

  10. Case Western Reserve U. Builds Virtual Campus to Woo Prospective Students

    Science.gov (United States)

    Young, Jeffrey R.

    2007-01-01

    This article describes a virtual world program that Case Western University administrators built using Second Life. It is designed for use by prospective students, who can tour the campus online. The program shows campus buildings, athletic facilities, a diner, and a virtual dormitory with window views of the athletics fields, a feature of the…

  11. Historiografia e identidade urbana no suk de Santa Catarina (décade de 1970

    Directory of Open Access Journals (Sweden)

    Dorval do Nascimento

    2007-01-01

    Full Text Available The aim of this work isto reflect the relations of the historiographywith the official memoryand the urban identity, taking ascenter of the analysis a set of workmanshipsproduced in the South ofSanta Catarina in the 1970 decade.This period is considered basic inthe process of identity transformationsin which the cities of thecarboniferous region were goingthrough. In a certain way there is anintention to consider the inflectionsof the local historiography in theurban identity.

  12. Wooing the Dark Continent: U.S. and China Engagement Strategy in Africa, is it Complimentary or Competition

    Science.gov (United States)

    2008-05-01

    Sidirpoulous, with Nastasya Tay and Romy Chevallier, China in Africa in the 21st Century: Preparing for the Forum on China Africa Cooperation, November...forums.csis.org/africa/?p=34 (accessed 25 February 2008). 60 Sidirpoulous, Elizabeth with Nastasya Tay, and Romy Chevallier. China in Africa in the 21st Century

  13. Analysis of three types of triterpenoids in tetraploid white birches (Betula platyphylla Suk.) and selection of plus trees

    Institute of Scientific and Technical Information of China (English)

    Sui Wang; Hui Zhao; Jing Jiang; Guifeng Liu; Chuanping Yang

    2015-01-01

    Betulin, oleanolic acid, and betulinic acid are naturally occurring pentacyclic triterpenoids that have significant medicinal value. Considerable amounts of these triterpenoids are available in the outer bark of white birch. In this study, we used ultrasound-assisted extraction (UAE) to extract triterpenoids from birch bark rapidly and with high efficiency. Using high performance liquid chro-matography (HPLC), three types of triterpenoids were separated and detected. We examined the differences among triterpenoids extracted from diploid versus tetra-ploid white birch. Then, we used factor analysis to screen out tetraploid white birches with comprehensively excel-lent performance. The results indicate that the optimum conditions for extraction include the use of ethanol as an extraction solvent, a solid-to-liquid ratio of 0.1 g/10 ml, ultrasonic power set at 100 W, a temperature of 60 ?C and an extraction time of 15 min. A reversed-phase C18 col-umn (4.6 mm 9 250 mm 9 5 lm) with a column tem-perature of 30 ?C and the mobile phase composed of A (acetonitrile) and B (0.1% aqueous phosphoric acid, v/v) at a flow rate of 0.5 ml/min were used, and the detection wavelength was 195 nm. No significant difference was observed between diploid and tetraploid white birch in terms of the content of three types of triterpenoids (at a confidence level of 0.05). As triterpenoid content, height, and DBH (diameter at breast height) are strongly interre-lated, we used factor analysis to evaluate all individuals, and we screened out six plus trees with excellent com-prehensive characters.

  14. To Twitter to Woo: Harnessing the power of social media (SoMe) in nurse education to enhance the student's experience.

    Science.gov (United States)

    Sinclair, Wendy; McLoughlin, Moira; Warne, Tony

    2015-11-01

    This paper explores some of the difficulties, challenges and rewards for student nurses and nurse academics when harnessing social media (SoMe) as part of the overall learning experience. The paper draws upon data in the form of student voices, captured through an online planned Twitter chat. This data analysis provides the basis of a case study on the student experience in practice placements. A planned 1 h Twitter chat took place in June 2013, specifically aimed at student nurses. What transpired was an illuminating debate, eliciting responses from around the globe about learning in practice, mentors, and student support that lasted over 3 h. More importantly, the Twitter chat also included qualified nurses and mentors, listening and responding in real time, offering thoughts and solutions to how support and mentoring could be improved. This was in contrast to how students, locally, currently use a paper based questionnaire to give feedback in isolation. The authenticity of this feedback is often compromised by university link lecturers' who often provide a more sanitised version of this feedback to clinical placement. This paper explores whether it is possible to facilitate a realignment and capture the zeitgeist in order to provide the opportunity for enhancing learning in practice. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Is the Use of Video Conferencing and Supporting Technologies a Feasible and Viable Way to Woo Farmers Back into Farmer Education?

    Science.gov (United States)

    Brown, Margaret; Fraser, Tom

    2011-01-01

    North Dakota State University (USA) have been using video conferencing as a delivery mode for farmer education for about twenty years and report that their farmers find this delivery method both practical and worthwhile. With the number of New Zealand farmers attending learning events decreasing, due mainly to time and cost, maybe it is time to…

  16. SUK- A companion to promoting well-being among overweight hypertensive older people : Health seeking behavior among overweight hypertensive older people

    OpenAIRE

    Seesawang, Junjira

    2011-01-01

    Health seeking behaviour is important in older people with hypertension and overweight, in terms of managing health factors that are related to their health and illness. However, health seeking behaviour of Thai older people is not well documented. This qualitative study aimed to describe health seeking behaviour of overweight hypertensive older people. Seven older women and three men participated in this study through purposive sampling. Qualitative data were gathered via in-depth interviews...

  17. The Effect of Hominis Placenta Herbal Acupuncture on Bell's palsy

    Directory of Open Access Journals (Sweden)

    Yun Jeong-hun

    2000-07-01

    Full Text Available This report was done to observe the effect of Hominis placenta herbal acupuncture on Bell's palsy. The study group comprised 16 patients who arrived at Woo-suk university oriental hospital from January, 1999 till January, 2000 for Bell's palsy. All patients were divided into two group. One was herbal acupunture group, and the other was control group. Acupunture group was done herbal acupuncture therapy on the facial acupuncture points. Followings are achievement and a term of each group. In herbal acupuncture group, 100% motor recovery was 7 case, 75% was 1 case, and 25% motor recovery term was 7.38±5.21 days, 50% was 11.00±6.16 days, 75% was 15.13±9.55 days, 100% was 23.14±7.97 days. In control group, 100% motor recovery was 4 case, 75% was 2 case, 25% below was 2 case and 25% motor recovery term was 11.17±4.96days, 50% was 18.17±6.82 days, 75% was 29.50±6.95 days, 100% was 44.00±11.49 days. The above results indicate that Hominis placenta herbal acupuncture is a useful effect on Bell's palsy. thus, continuous herbal acupunture study will be needed for more clinical application on Bell' palsy.

  18. Quantitative measurements of C-reactive protein using silicon nanowire arrays

    Directory of Open Access Journals (Sweden)

    Min-Ho Lee

    2008-03-01

    Full Text Available Min-Ho Lee, Kuk-Nyung Lee, Suk-Won Jung, Won-Hyo Kim, Kyu-Sik Shin, Woo-Kyeong SeongKorea Electronics Technology Institute, Gyeonggi, KoreaAbstract: A silicon nanowire-based sensor for biological application showed highly desirable electrical responses to either pH changes or receptor-ligand interactions such as protein disease markers, viruses, and DNA hybridization. Furthermore, because the silicon nanowire can display results in real-time, it may possess superior characteristics for biosensing than those demonstrated in previously studied methods. However, despite its promising potential and advantages, certain process-related limitations of the device, due to its size and material characteristics, need to be addressed. In this article, we suggest possible solutions. We fabricated silicon nanowire using a top-down and low cost micromachining method, and evaluate the sensing of molecules after transfer and surface modifications. Our newly designed method can be used to attach highly ordered nanowires to various substrates, to form a nanowire array device, which needs to follow a series of repetitive steps in conventional fabrication technology based on a vapor-liquid-solid (VLS method. For evaluation, we demonstrated that our newly fabricated silicon nanowire arrays could detect pH changes as well as streptavidin-biotin binding events. As well as the initial proof-of-principle studies, C-reactive protein binding was measured: electrical signals were changed in a linear fashion with the concentration (1 fM to 1 nM in PBS containing 1.37 mM of salts. Finally, to address the effects of Debye length, silicon nanowires coupled with antigen proteins underwent electrical signal changes as the salt concentration changed.Keywords: silicon nanowire array, C-reactive protein, vapor-liquid-solid method

  19. Respiratory syncytial virus-like nanoparticle vaccination induces long-term protection without pulmonary disease by modulating cytokines and T-cells partially through alveolar macrophages

    Directory of Open Access Journals (Sweden)

    Lee YT

    2015-07-01

    Full Text Available Young-Tae Lee,1,* Eun-Ju Ko,1,2,* Hye Suk Hwang,1,2 Jong Seok Lee,1,3 Ki-Hye Kim,1 Young-Man Kwon,1 Sang-Moo Kang1,2 1Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, 2Department of Biology, Georgia State University, Atlanta, GA, USA; 3National Institute of Biological Resources, Incheon, South Korea *These authors contributed equally to this work Abstract: The mechanisms of protection against respiratory syncytial virus (RSV are poorly understood. Virus-like nanoparticles expressing RSV glycoproteins (eg, a combination of fusion and glycoprotein virus-like nanoparticles [FG VLPs] have been suggested to be a promising RSV vaccine candidate. To understand the roles of alveolar macrophages (AMs in inducing long-term protection, mice that were 12 months earlier vaccinated with formalin-inactivated RSV (FI-RSV or FG VLPs were treated with clodronate liposome prior to RSV infection. FI-RSV immune mice with clodronate liposome treatment showed increases in eosinophils, plasmacytoid dendritic cells, interleukin (IL-4+ T-cell infiltration, proinflammatory cytokines, chemokines, and, in particular, mucus production upon RSV infection. In contrast to FI-RSV immune mice with severe pulmonary histopathology, FG VLP immune mice showed no overt sign of histopathology and significantly lower levels of eosinophils, T-cell infiltration, and inflammatory cytokines, but higher levels of interferon-γ, which are correlated with protection against RSV disease. FG VLP immune mice with depletion of AMs showed increases in inflammatory cytokines and chemokines, as well as eosinophils. The results in this study suggest that FG nanoparticle vaccination induces long-term protection against RSV and that AMs play a role in the RSV protection by modulating eosinophilia, mucus production, inflammatory cytokines, and T-cell infiltration. Keywords: alveolar macrophage, nanoparticle vaccine, VLP, FI-RSV, RSV disease

  20. 白桦提取物对大鼠下丘脑组织中5-HT含量的影响*%Effect Betula HaatyphyHa suk(BPS) Extract on 5- HT Hypothalamus of Rats

    Institute of Scientific and Technical Information of China (English)

    杜旭; 刘璐; 薛欣

    2001-01-01

    目的研究白桦提取物对酵母致大鼠发热的影响及对下丘脑组织中5-HT含量的影响.为其解热降温机理作用提供依据.方法用荧光分光光度计在480nm/365nm处测定5-HT含量.单位以每mg鲜脑组织含5-HT的ng数表示.结果酵母模型组大鼠体温及下丘脑组织中5-HT含量均明显高于正常对照组,给药组大鼠给予白桦提取物后1h体温显著下降,下丘脑组织中5-HT含量亦明显降低.讨论本实验结果显示:白桦提取物对酵母致发热大鼠有明显的解热作用,其解热作用与影响体温调节中枢介质5-HT的含量有关.

  1. Practical Implementation of New Particle Tracking Method to the Real Field of Groundwater Flow and Transport.

    Science.gov (United States)

    Suk, Heejun

    2012-01-01

    In articles published in 2009 and 2010, Suk and Yeh reported the development of an accurate and efficient particle tracking algorithm for simulating a path line under complicated unsteady flow conditions, using a range of elements within finite elements in multidimensions. Here two examples, an aquifer storage and recovery (ASR) example and a landfill leachate migration example, are examined to enhance the practical implementation of the proposed particle tracking method, known as Suk's method, to a real field of groundwater flow and transport. Results obtained by Suk's method are compared with those obtained by Pollock's method. Suk's method produces superior tracking accuracy, which suggests that Suk's method can describe more accurately various advection-dominated transport problems in a real field than existing popular particle tracking methods, such as Pollock's method. To illustrate the wide and practical applicability of Suk's method to random-walk particle tracking (RWPT), the original RWPT has been modified to incorporate Suk's method. Performance of the modified RWPT using Suk's method is compared with the original RWPT scheme by examining the concentration distributions obtained by the modified RWPT and the original RWPT under complicated transient flow systems.

  2. Recent advances in elasticity, viscoelasticity and inelasticity

    CERN Document Server

    Rajagopal, KR

    1995-01-01

    This is a collection of papers dedicated to Prof T C Woo to mark his 70th birthday. The papers focus on recent advances in elasticity, viscoelasticity and inelasticity, which are related to Prof Woo's work. Prof Woo's recent work concentrates on the viscoelastic and viscoplastic response of metals and plastics when thermal effects are significant, and the papers here address open questions in these and related areas.

  3. The Poetic Romance Of Oriental Violence Esthetics——A Brief Analysis Of The Violent Beauty Images In The Early Works Of John Woo%东方暴力美学的浪漫诗意——浅析吴宇森早期作品中的暴力美学意象

    Institute of Scientific and Technical Information of China (English)

    杨甜子

    2010-01-01

    作为"暴力美学"影片的缔造者与完善者,吴宇森的电影作品总是在动作与枪战中带给观众无尽的惊喜.而这样的风格在他的早期作品如等影片中表现的尤为突出.作为中国导演闯荡好莱坞的杰出代表,吴宇森电影中的暴力美学意象值得我们深入探讨和研究.

  4. The Violence Movies In Different Cultural Background——A Case Study Of John Woo Yu-Sen's And Quentin Tarantino's Movies"%不同文化背景下的暴力电影——以吴宇森、昆廷·卡伦蒂诺为例

    Institute of Scientific and Technical Information of China (English)

    刘吉磊

    2009-01-01

    香港导演吴宇森和美国导演昆廷·塔伦蒂诺的暴力影片,文化背景不同、叙述风格各异,从两者不同的价值取向以及对暴力电影传统的继承与革新等方面进行比较和分析,可寻找出当今影坛"暴力美学"的基本走向.

  5. An Analysis of the Performance of Beethoven's "32 Variations in C Minor" WoO80%浅析贝多芬《c小调32变奏曲》WoO80的演奏

    Institute of Scientific and Technical Information of China (English)

    钟俊

    2011-01-01

    Besides composing 32 piano sonatas,"Music Emperor" Beethoven also had another prolific field,that is in partita.And of all his compositions the most famous one is the《32 Variations in C Minor》composed in his metaphase.Most of Beethoven's partitas have very pop contents and very familiar rhythms,just like Mozart's compostions.But this partita's topic rhythm breaks Beethoven's ordinary style and becomes a very popular composition often performed in concerts.The author of this thesis is studying on this composion from multi-angle including timbre,music comprehension and practice of methods.So when the pure and religious classic style can be well combined with profound feelings in the piano performance,the《32 Variations in C Minor》will be played perfectly.%"乐圣"贝多芬除创作32首钢琴奏鸣曲以外,变奏曲便是他创作的另一块丰富的领域了。其中,要数他在中期阶段创作的《c小调32变奏曲》最为著名。贝多芬创作的变奏曲大部分都跟莫扎特一样,以通俗性为内容,主题大都为大家较为熟悉的旋律。而这首变奏曲主题旋律则突破了贝多芬的常规,风格独树一帜,是一首深受大众欢迎的音乐会变奏曲。笔者从曲式结构、音乐理解、技术运用等多个角度对这一作品进行了研究分析,阐述各变奏演奏的具体方法,以便将纯正严谨的古典风格与深刻的感情有机地结合在钢琴的演奏上,从而将其表现得更加完美。

  6. Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34-deoxycholic acid nanocomplex

    Directory of Open Access Journals (Sweden)

    Hwang SR

    2016-08-01

    Full Text Available Seung Rim Hwang,1 Dong-Hyun Seo,2 Youngro Byun,3 Jin Woo Park4 1Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju, 2Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Gangwon, 3Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, College of Pharmacy, Seoul National University, Seoul, 4Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Muan-gun, Jeonnam, Republic of Korea Abstract: The N-terminal 34-amino-acid peptide fragment of human parathyroid hormone PTH (1-34, is used clinically to treat osteoporosis; however, it is currently administered by a once-daily subcutaneous injection, resulting in poor patient compliance. We have developed enteric microcapsules containing an ionic nanocomplex between PTH (1-34 and lysine-linked deoxycholic acid (LysDOCA for the oral delivery of PTH (1-34. We measured the particle size of the PTH/LysDOCA complex and assessed its biological activity by determining the cAMP content in MC3T3-E1 cells. We also assessed its permeability across a Caco-2 cell monolayer and the bioavailability of the intrajejunally administered PTH/LysDOCA complex compared with PTH (1-34 in rats. In addition, the antiosteoporotic activity of the PTH/LysDOCA complex, encapsulated in an enteric carrier by coaxial ultrasonic atomization, was evaluated after it was orally administered to ovariectomized (OVX rats. The formation of an ionic complex between PTH (1-34 and LysDOCA produced nanoparticles of diameter 33.0±3.36 nm, and the bioactivity of the complex was comparable with that of PTH (1-34. The Caco-2 cell permeability and AUClast value of the PTH/LysDOCA (1:10 nanocomplex increased by 2.87- and 16.3-fold, respectively, compared with PTH (1-34 alone. Furthermore, the OVX rats treated with oral PTH/LysDOCA-loaded enteric microcapsules showed an

  7. The Effect of Defense R&D Expenditures on Military Capability and Technological Spillover

    Science.gov (United States)

    2013-03-01

    offshore oil and the high level of social infrastructure, which skews its per capita measurements. Hwang (2008) proposed another measure of national...RANK Morocco 0.10989 0.139331781 36 Indonesia 0.102897 0.130465213 37 North Korea 0.10274 0.130266149 38 Belgium 0.10258 0.130063282 39... Morocco 0.0044709 37 16710894414 71 55 COUNTRY CINC* CINC RANK HWANG ** HWANG RANK Syrian Arab Republic 0.0044535 38 52945275034 53

  8. 75 FR 69160 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-11-10

    ... Kington Kin Bong Hui Kwok-Kit Hui Man Yan Mark Hui Ng Suk Ha Hung Janet Yi Kui Hung San-Hsiung Husain Syed... Dalina Abdul Sarmiento Sonia Satrap Alireza Saumweber Helena Maria Schatz John Barkley Scherer...

  9. Tennisemusketärid / Paavo Kangur

    Index Scriptorium Estoniae

    Kangur, Paavo, 1966-

    2007-01-01

    Treener Cyril Suk vormib mitmekordsest Eesti tennisemeistrist Jürgen Zoppist Praha tenniseakadeemias maailmaklassimängijat. Kommenteerib Eesti tennisekoondise peatreener Peeter Lamp. Vt. samas ka lühivestlust Jürgen Zoppiga

  10. Fundamentalismi ja tehnoloogia võitlus / Ülo Niinemets

    Index Scriptorium Estoniae

    Niinemets, Ülo, 1970-

    2003-01-01

    Autori sõnul eelistatakse Eestis fundamentaaluuringutele rakendusuuringuid. Poliitilise tahte puudumine on pannud meie teaduse Euroopa kontekstis täbarasse olukorda, leiab ta ning pakub olukorrast väljapääsuks integreerumist Euroopa teadusinstituutidega

  11. General characteristics of causes of urban flood damage and flood forecasting/warning system in Seoul, Korea Young-Il Moon1, 2, Jong-Suk Kim1, 2 1 Department of Civil Engineering, University of Seoul, Seoul 130-743, South Korea 2 Urban Flood Research Inst

    Science.gov (United States)

    Moon, Young-Il; Kim, Jong-Suk

    2015-04-01

    Due to rapid urbanization and climate change, the frequency of concentrated heavy rainfall has increased, causing urban floods that result in casualties and property damage. As a consequence of natural disasters that occur annually, the cost of damage in Korea is estimated to be over two billion US dollars per year. As interest in natural disasters increase, demands for a safe national territory and efficient emergency plans are on the rise. In addition to this, as a part of the measures to cope with the increase of inland flood damage, it is necessary to build a systematic city flood prevention system that uses technology to quantify flood risk as well as flood forecast based on both rivers and inland water bodies. Despite the investment and efforts to prevent landside flood damage, research and studies of landside-river combined hydro-system is at its initial stage in Korea. Therefore, the purpose of this research introduces the causes of flood damage in Seoul and shows a flood forecasting and warning system in urban streams of Seoul. This urban flood forecasting and warning system conducts prediction on flash rain or short-term rainfall by using radar and satellite information and performs prompt and accurate prediction on the inland flooded area and also supports synthetic decision-making for prevention through real-time monitoring. Although we cannot prevent damage from typhoons or localized heavy rain, we can minimize that damage with accurate and timely forecast and a prevention system. To this end, we developed a flood forecasting and warning system, so in case of an emergency there is enough time for evacuation and disaster control. Keywords: urban flooding, flood risk, inland-river system, Korea Acknowledgments This research was supported by a grant (13AWMP-B066744-01) from Advanced Water Management Research Program (AWMP) funded by Ministry of Land, Infrastructure and Transport of Korean government.

  12. 77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-07-27

    ... KEEHOWAN KIM MI LIE KIM MYUNG OK KIM YEONG JUN KONDRATIEV MARIE NADEJDA KOO DOROTHEA GERALDINE KRAMER... LEE ANDREW HENRY LEE BONG LEE DENNIS JEE-WOO DEAN LEE TONY KWOK CHEN LEE VICTORIA KATIE LEE WENDY WAI... WOO TRACY YANG BESSIE SHIH-FUN YEN RICHARD TSAN KWONG YEUNG ANDREW YEUNG CARMEN YI HYON SUN YI...

  13. PEOPLE/POINTS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Wooing Movie GoersAfter 16 years directing Hollywood movies, John Woo Yu-sen is back with an ambitious historical epic titled Red Cliff. The world premiere was held at the Memorial of Marquis Zhuge Liang, a major char- acter in the blockbuster film,

  14. Main: 1LR5 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available hall, J.Bauley, J.-G.Chen, M.Venis, R.M.Napier, R.W.Pickersgill E.J.Woo, J.Marshall...Aux311; Zea Mays Molecule: Auxin Binding Protein 1; Chain: A, B, C, D; Engineered: Yes; Mutation: Yes Protein Binding E.J.Woo, J.Mars

  15. SELES

    DEFF Research Database (Denmark)

    Garcia-Zamora, Claudia; Rodriguez-Henriquez, Francisco; Ortiz-Arroyo, Daniel

    2005-01-01

    In this paper we present an improved e-voting protocol for online elections based on the scheme proposed by Lin--Hwang--Chang. We show that Lin--Hwang--Chang's scheme has two important weaknesses. We describe in detail our findings and propose a new scheme to overcome these weaknesses effectively...

  16. Reference: 120 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 120 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u15494553i Hwang Hau-Hsuan...that interact with VirB2, the Agrobacterium tumefaciens pilin protein, mediate plant transformation. 11 3148-67 15494553 2004 Nov The Plant cell Gelvin Stanton B|Hwang Hau-Hsuan

  17. The rectilinear Steiner ratio

    Directory of Open Access Journals (Sweden)

    PO de Wet

    2005-06-01

    Full Text Available The rectilinear Steiner ratio was shown to be 3/2 by Hwang [Hwang FK, 1976, On Steiner minimal trees with rectilinear distance, SIAM Journal on Applied Mathematics, 30, pp. 104– 114.]. We use continuity and introduce restricted point sets to obtain an alternative, short and self-contained proof of this result.

  18. Committees

    Science.gov (United States)

    2012-11-01

    Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro

  19. Extending raw materials ordering policy with genetic algorithm%用遗传算法拓展原材料的采购策略

    Institute of Scientific and Technical Information of China (English)

    余玉刚; 梁樑; 王志强

    2004-01-01

    A fractional-integral multiple ordering method was proposed to improve the integral multiple ordering method in material procurements. To illustrate the improvement effect, a new model considering a fractional-integral multiple ordering method was presented to extend the model proposed by Woo, Hsu, and Wu (2001), and a genetic algorithm was developed to resolve the modified model. Finally a numerical study based on the example used by Woo, Hsu, and Wu was presented to illustrate that the proposed model provided a lower or equal joint total relevant cost compared with Woo, Hsu, and Wu's model.

  20. Revision of the genus Salganea Stål (Blattodea, Blaberidae, Panesthiinae from China, with descriptions of three new species

    Directory of Open Access Journals (Sweden)

    Xiudan Wang

    2014-05-01

    Full Text Available Three new species of Salganea Stål, 1877 are described and illustrated: S. quinquedentata sp. n., S. anisodonta sp. n. and S. flexibilis sp. n. S. taiwanensis Roth, 1979, S. guangxiensis (Feng & Woo, 1990, S. incerta (Brunner von Wattenwyl, 1893 and S. raggei Roth, 1979 are redescribed. Panesthia concinna Feng & Woo, 1990 is synonymized with S. taiwanensis Roth, 1979 and Panesthia guangxiensis Feng & Woo, 1990 is transferred to the genus Salganea for the first time. As well, a key to species from China is presented.

  1. Souli millenniumivärav / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    Millenniumi tähistamiseks Souli plaanitavast hiigelehitisest "Souli ring", mis peaks valmima 2003. a. Arhitektuurse lahenduse autorid Lee Eun-seok ja Woo Dae-seung firmast Op'us Architects & Co. Eri ringkondade arvamusi projekti kohta.

  2. Eto vam ne Dzheims Bond / Vincent Vega

    Index Scriptorium Estoniae

    Vega, Vincent

    2000-01-01

    Actionfilmi "Võimatu missioon" ("Mission : Impossible") järg "Võimatu Missioon 2 ("Mission : Impossible II") : režissöör John Woo : peaosaline ja produtsent Tom Cruise : Ameerika Ühendriigid 2000

  3. Eto vam ne Dzheims Bond / Vincent Vega

    Index Scriptorium Estoniae

    Vega, Vincent

    2000-01-01

    Actionfilmi "Võimatu missioon" ("Mission : Impossible") järg "Võimatu Missioon 2 ("Mission : Impossible II") : režissöör John Woo : peaosaline ja produtsent Tom Cruise : Ameerika Ühendriigid 2000

  4. Kes kardab Park Chan-Wooki? / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2007-01-01

    Vägivalla ajendite teemadel. USA meedia süüdistas peale Virginia koolitulistamist filmikunsti. Seoseid ja/või põhjusi otsiti korealase Park Chan-Wooki filmist "Vana poiss" ("Old Boy") ja John Woo filmidest

  5. Kes kardab Park Chan-Wooki? / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2007-01-01

    Vägivalla ajendite teemadel. USA meedia süüdistas peale Virginia koolitulistamist filmikunsti. Seoseid ja/või põhjusi otsiti korealase Park Chan-Wooki filmist "Vana poiss" ("Old Boy") ja John Woo filmidest

  6. Comparison of the G-174C polymorphism of interleukin (IL)-6 in ...

    African Journals Online (AJOL)

    enoh

    2012-04-05

    Apr 5, 2012 ... binding site for the transcription factor NF-1, resulting in repressed ... leukocyte pellet using a DNA extraction kit (AXYGEN, California,. USA). .... S, Woo P (1998) The effect of novel polymorphisms in the interleukin-. 6 (IL-6) ...

  7. The effect of clove-based herbal mouthwash on radiation-induced oral mucositis in patients with head and neck cancer: a single-blind randomized preliminary study

    Directory of Open Access Journals (Sweden)

    Kong M

    2016-07-01

    Full Text Available Moonkyoo Kong,1 Deok-Sang Hwang,2 Seong Woo Yoon,3 Jinsung Kim4 1Department of Radiation Oncology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, 2Department of Korean Medicine Obstetrics & Gynecology, Kyung Hee University Medical Center, 3Department of Korean Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong, 4Department of Korean Internal Medicine, Kyung Hee University Medical Center, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea Purpose: This study was performed to evaluate the efficacy and safety of clove-based herbal mouthwash in ameliorating radiation-induced oral mucositis in patients with head and neck cancer. Methods: Fourteen patients were prospectively enrolled in this study and randomized to either an experimental group or a control group. The patients of the experimental group swished their mouths with a clove-based herbal mouthwash during radiotherapy (RT, while the patients of the control group swished with clear water. The primary end point of this study was incidence of radiation-induced oral mucositis. The secondary end points were time to onset of radiation-induced oral mucositis, duration of radiation-induced oral mucositis, incidence of supplemental nutrition through feeding tube, maximum pain score, body weight loss, incidence of RT interruption, and duration of RT interruption. Results: The use of clove-based herbal mouthwash shortened the duration of grade ≥2 mucositis (24.3 days vs 37.1 days, P=0.044 and reduced body weight loss during RT (3.1% vs 7.4%, P=0.023 compared with clear water. The use of clove-based herbal mouthwash also reduced the incidence of grade 3 mucositis (28.6% vs 57.1%, supplemental nutrition (0% vs 28.6%, and RT interruption (14.3% vs 28.6%, and reduced the duration of grade 3 mucositis (5.1 days vs 17.7 days and RT interruption (1 days vs 8.5 days. In addition, clove-based herbal mouthwash

  8. Discrepancies between modified Medical Research Council dyspnea score and COPD assessment test score in patients with COPD

    Directory of Open Access Journals (Sweden)

    Rhee CK

    2015-08-01

    Full Text Available Chin Kook Rhee,1 Jin Woo Kim,2 Yong Il Hwang,3 Jin Hwa Lee,4 Ki-Suck Jung,3 Myung Goo Lee,5 Kwang Ha Yoo,6 Sang Haak Lee,7 Kyeong-Cheol Shin,8 Hyoung Kyu Yoon9 1Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, 3Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, 5Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, 6Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 8Regional Center for Respiratory Disease, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, 9Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Background and objective: According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD guidelines, either a modified Medical Research Council (mMRC dyspnea score of ≥2 or a chronic obstructive pulmonary disease (COPD assessment test (CAT score of ≥10 is considered to represent COPD patients who are

  9. On Gallimard's Narcissistic Personality in M. Butterfly

    Institute of Scientific and Technical Information of China (English)

    Zhao Lanfeng

    2009-01-01

    The anti-orientalism in David Hwang's M. Butterfly has been discussed by many critics, but here it will be analyzed with the help of psychology. From the perspective of psychoanalysis, Gallimard's narcissistic personality is the root of his tragedy.

  10. Biomonitoring: Guide for the Use of Biological Endpoints in Monitoring Species, Habitats, and Projects

    Science.gov (United States)

    2007-11-01

    Disruptors . Pages 369-430 in: R. Kendall, R. Dickerson, J. Geisy, and W. Suk, eds., Principles and Processes for Evaluating Endocrine Disruptors ...Olympia, WA. Sheffield, S.R., J.M. Matter, B.A. Rattner, and P.D. Guiney 1998. Fish and Wildlife Species as Sentinels of Environmental Endocrine

  11. Mõtisklus kivirannal : Visby rahvusvaheline heliloojate keskus kui loominguline pelgupaik / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2008-01-01

    Gotlandi saarel asuvast heliloojate keskusest. Lühiintervjuu hiljuti keskuses töötanud kahe heliloojaga - Lõuna-Koreast pärit, ent Floridas elava Suk-Jun Kim'i ja Lõuna-Aafrikast vabariigist pärit Clare Loveday'ga

  12. Kunst rahvani ehk Kwangju biennaal / Siram

    Index Scriptorium Estoniae

    Siram, pseud., 1968-

    2004-01-01

    Biennaal "Tolmutera, veetilk" Lõuna-Koreas, avatud kuni 13. XI 2004. Kuraatorid Yongwoo Lee (New York, Soul), Kerry Brougher (Washington-distrikt), Suk-won Chang (Kwangju). City Light Award - Watercio Caldas (Brasiilia), Korea fondi preemia - Jennifer Allora ja Guillermo Calzadilla (Kuuba) jt. Johann Köleri nim. Positivistlik Kunsttööstuskool osales biennaali performance'iprogrammis

  13. Med Kingo på dybt vand

    DEFF Research Database (Denmark)

    Arndal, Lars Stubbe

    2014-01-01

    Tag med digteren Thomas Kingo ud på dybt vand i selskab med lektor og mag.art. Lars Arndal, der kaster nye perspektiver på Kingos forlisdigt Hierte-Suk. Arndal kommer hermed også med et bud på, hvordan man som lærer kan invitere eleverne med på opdagelse i digtet...

  14. Kunst rahvani ehk Kwangju biennaal / Siram

    Index Scriptorium Estoniae

    Siram, pseud., 1968-

    2004-01-01

    Biennaal "Tolmutera, veetilk" Lõuna-Koreas, avatud kuni 13. XI 2004. Kuraatorid Yongwoo Lee (New York, Soul), Kerry Brougher (Washington-distrikt), Suk-won Chang (Kwangju). City Light Award - Watercio Caldas (Brasiilia), Korea fondi preemia - Jennifer Allora ja Guillermo Calzadilla (Kuuba) jt. Johann Köleri nim. Positivistlik Kunsttööstuskool osales biennaali performance'iprogrammis

  15. Global HRD.

    Science.gov (United States)

    1997

    This document contains four papers from a symposium on global human resource development (HRD). "Globalization of Human Resource Management (HRM) in Government: A Cross-Cultural Perspective" (Pan Suk Kim) relates HRM to national cultures and addresses its specific functional aspects with a unique dimension in a global organization.…

  16. Why Stochastic Modeling is Essential in Analyzing Interdicted Transportation Network Performance

    Science.gov (United States)

    1989-06-01

    Guro -Gu, Si-Heung 1 Dong, HanYang Apt. 5-1107 Seoul, Korea 11. CPT. Kim, Suk Hwan SMC 2318 Naval Postgraduate School Monterey, alifornia 93943-5000 12. Library 130-02 Korea Military Academy Gong-Reung Dong, 556-21 Seoul, Korea 61

  17. Rasch analysis of the Western Ontario Osteoarthritis of the Shoulder index – the Danish version

    Directory of Open Access Journals (Sweden)

    Moeini S

    2016-11-01

    Full Text Available Sahar Moeini,1 Jeppe V Rasmussen,1 Tobias W Klausen,2 Stig Brorson1 1Department of Orthopedic Surgery, 2Department of Hematology, Herlev Hospital, Herlev, Denmark Purpose: The Western Ontario Osteoarthritis of the Shoulder (WOOS index is a disease-specific, patient-reported, 19-question survey that measures the quality of life among patients with osteoarthritis (OA. The purpose of this study was to validate the Danish version of WOOS for OA and fractures (FRs using modern test theory.Patients and methods: The study included 1,987 arthroplasties in 1,943 patients that were reported to the Danish Shoulder Arthroplasty Register between 2006 and 2011. These included 847 OA and 1,140 FR cases.Results: Principal component analysis indicated the unidimensionality of WOOS. The person reliabilities showed a floor-ceiling effect, indicating that a dichotomy was the best fit for the WOOS scale. For OA, WOOS showed good reliability (item and person reliability of 0.98 and 0.76 and good targeting, with a person mean of -0.56 logits. FR also showed good targeting (person mean of -0.08 and good reliability (item and person reliabilities of 1.00 and 0.86, respectively. All WOOS items fit well with the OA sample except items 5 and 6 (pertaining to grinding and the influence of weather. In addition, item 6 showed signs of degrading the scale with an outfit mean square of 2.46. Only item 6 showed a misfit for FR with no sign of scale degradation. The residual principal component analysis confirmed the unidimensionality of FR but not OA. Six items displayed clinically significant differential item functioning between OA and FR.Conclusion: Rasch analysis showed that WOOS had a good fit with the Rasch model when used as a dichotomous scale for OA and FR. However, the results were valid only when WOOS was divided into two categories with a threshold of 950 (50% of the maximum score. For the use of WOOS in future clinical research, we recommend that a dichotomous score

  18. EDITORIAL: Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010) Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010)

    Science.gov (United States)

    Takahashi, M.; Saito, H.

    2011-02-01

    overseas. The programme involved 4 plenary talks, 37 invited talks, 85 contributed talks and 352 posters. All submitted papers were reviewed in order to meet the standards of Journal of Physics D: Applied Physics and Journal of Physics: Conference Series. We are grateful to all participants for their valuable contributions and active discussions. We gratefully acknowledge the financial support of 17 Japanese companies and 7 Japanese foundations. Invited papers from ISAMMA 2010 Contents Current status and recent topics of rare-earth permanent magnets S Sugimoto Alloying effect on the magnetic properties of RFeB-type bulk magnets H W Chang, C C Hsieh, J Y Gan, Y T Cheng, M F Shih and W C Chang Coercivity distributions in Nd-Fe-B sintered magnets produced by the grain boundary diffusion process H Nakamura, K Hirota, T Ohashi and T Minowa Recent progress in high Bs Fe-based nanocrystalline soft magnetic alloys M Ohta and Y Yoshizawa Electric-field effects on magnetic anisotropy in Pd/Fe/Pd(0 0 1) surface Shinya Haraguchi, Masahito Tsujikawa, Junpei Gotou and Tatsuki Oda Gate modulation of spin precession in a semiconductor channel Hyun Cheol Koo, Jae Hyun Kwon, Jonghwa Eom, Joonyeon Chang, Suk Hee Han and Mark Johnson Ferromagnetic resonance of epitaxial Fe nanodots grown on MgO measured using coplanar waveguides M Mizuguchi and K Takanashi Switching phase diagrams of current-induced magnetization switching in asymmetric MgO-based magnetic tunnel junctions Seung-Young Park, Jae-Ho Han, Se-Chung Oh, Jang-Eun Lee, Kyung-Tae Nam, Hyun-Woo Lee, Younghun Jo and Kyung-Jin Lee Temperature dependence of spin-dependent transport properties of Co2MnSi-based current-perpendicular-to-plane magnetoresistive devices Y Sakuraba, K Izumi, S Bosu, K Saito and K Takanashi Adsorbate-induced spin-polarization enhancement of Fe3O4(0 0 1) A Pratt, M Kurahashi, X Sun and Y Yamauchi Antiferromagnetic coupling between spinel ferrite and α-Fe layers in Fe3-δO4/MgO/Fe(0 0 1) epitaxial films Hideto

  19. Rasch analysis of the Western Ontario Osteoarthritis of the Shoulder index - the Danish version

    DEFF Research Database (Denmark)

    Moeini, Sahar; Rasmussen, Jeppe V; Klausen, Tobias W

    2016-01-01

    PURPOSE: The Western Ontario Osteoarthritis of the Shoulder (WOOS) index is a disease-specific, patient-reported, 19-question survey that measures the quality of life among patients with osteoarthritis (OA). The purpose of this study was to validate the Danish version of WOOS for OA and fractures...... (FRs) using modern test theory. PATIENTS AND METHODS: The study included 1,987 arthroplasties in 1,943 patients that were reported to the Danish Shoulder Arthroplasty Register between 2006 and 2011. These included 847 OA and 1,140 FR cases. RESULTS: Principal component analysis indicated...... targeting (person mean of -0.08) and good reliability (item and person reliabilities of 1.00 and 0.86, respectively). All WOOS items fit well with the OA sample except items 5 and 6 (pertaining to grinding and the influence of weather). In addition, item 6 showed signs of degrading the scale with an outfit...

  20. ON IMPROVING AN INTEGRATED INVENTORY MODEL FOR A SINGLE VENDOR AND MULTIPLE BUYERS WITH A RELAXED MATERIAL ORDERING CYCLE POLICY

    Institute of Scientific and Technical Information of China (English)

    Yugang YU; Feng CHU; Haoxun CHEN

    2006-01-01

    In this paper, we propose a new model for improving the lot size obtained with the model of Woo, Hsu, and Wu (2001) proposed in their paper "An integrated inventory model for a single vendor and multiple buyers with ordering cost reduction" (Int. J. Production Economics 73 203-215). The new model can provide a lower or equal joint total cost as compared to Woo, Hsu, and Wu's model due to the relaxation of their integral multiple material ordering cycle policy to a fractional-integral multiple material ordering cycle policy. The proposed model is analyzed and an algorithm for calculating the optimal lot size of the model is developed. A numerical study based on the example used by Woo, Hsu, and Wu is presented.

  1. Resurfacing hemiarthroplasty compared to stemmed hemiarthroplasty for glenohumeral osteoarthritis

    DEFF Research Database (Denmark)

    Rasmussen, Jeppe V; Olsen, Bo S; Sorensen, Anne Kathrine

    2015-01-01

    PURPOSE: The aim of this study was to conduct a randomised, clinical trial comparing stemmed hemiarthroplasty and resurfacing hemiarthroplasty in the treatment of glenohumeral osteoarthritis. METHODS: A total of 40 shoulders (35 patients) were randomised to stemmed hemiarthroplasty or resurfacing...... hemiarthroplasty and evaluated three and 12 months postoperatively using the Constant-Murley score (CMS) and Western Ontario Osteoarthritis of the Shoulder (WOOS) index. RESULTS: There were no statistically significant differences in age, gender or pre-operative scores except for WOOS at baseline. Two patients...

  2. POSTERS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Natural Toxins   S01 Susceptibility of Edible Bihalves to Paralytic Shellfish Poisons and Their Donor   Ya-Hui Li* , Deng-Fwu Hwang, Jou-Fang Deng, Taibei, China      S02 Food Safety of Grass Carp Bile Juice   Deng-Fwu Hwang* , Yen-Hung Yeh, Jou-Feng Deng, Taibei, China      S03 Differentiation of Muscular Proteins from Toxic and Non Toxic Puffers   Tai-Yuan Chen* , Deng-Fwu Hwang, Taibei, China      S04 Radiation Resistance of Paralytic Shellfish Poison (PSP) Toxins   Terestia P Acevedo, Philippines

  3. On the Security of a Simple Three-Party Key Exchange Protocol without Server’s Public Keys

    Directory of Open Access Journals (Sweden)

    Junghyun Nam

    2014-01-01

    Full Text Available Authenticated key exchange protocols are of fundamental importance in securing communications and are now extensively deployed for use in various real-world network applications. In this work, we reveal major previously unpublished security vulnerabilities in the password-based authenticated three-party key exchange protocol according to Lee and Hwang (2010: (1 the Lee-Hwang protocol is susceptible to a man-in-the-middle attack and thus fails to achieve implicit key authentication; (2 the protocol cannot protect clients’ passwords against an offline dictionary attack; and (3 the indistinguishability-based security of the protocol can be easily broken even in the presence of a passive adversary. We also propose an improved password-based authenticated three-party key exchange protocol that addresses the security vulnerabilities identified in the Lee-Hwang protocol.

  4. Variational Estimation of Wave-affected Parameters in a Two-equation Turbulence Model

    Science.gov (United States)

    2014-01-01

    time 2 intervals within the assimilation window, where ijT , and obsT are the simulated and 3 observed temperature at location i and time level j. N...16 downwelling. Journal of Physical Oceanography, 32: 2171-2193. 17 Agrawal, Y.C., Terray, E.A., Donelan, M.A., Hwang, P.A., Williams , A. J...Y., Drennan, W.M., Kahma, K., Williams III, A. 7 J., Hwang, P., Kitaigorodskii, S. A., 1996. Estimates of kinetic energy 8 dissipation under

  5. Nonlinear Photonic Systems for V- and W-Band Antenna Remoting Applications

    Science.gov (United States)

    2016-10-22

    AFRL-AFOSR-JP-TR-2016-0088 Nonlinear Photonic Systems for V- and W-Band Antenna Remoting Applications Sheng-Kwang Hwang NATIONAL CHENG KUNG... Antenna Remoting Applications 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-15-1-4026 5c.  PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Sheng-Kwang Hwang...TERMS nonlinear, photonic, antenna , remote, microwave, amplification, bandwith, modulation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR

  6. Prepare to be Wrong: Assessing and Designing for Adaptability, Flexibility, and Responsiveness

    Science.gov (United States)

    2013-04-01

    Astronautica 53, Issue 12 (December 2003): 927–944. 15 Richard de Neufville and Stefan Scholtes, Flexibility in Engineering Design (Cambridge: MIT Press...for Aerospace Systems,” Acta Astronautica 53, Issue 12 (December 2003), 938. Figure 1. Types of System Design A. Framework for Assessment and...Implications for Aerospace Systems.” Acta Astronautica 53, Issue 12 (December 2003): 927–944. B-3 Suh, Eun Suk, Olivier de Weck, Il Yong Kim, and David

  7. Trans World Tidal Gravity Profile.

    Science.gov (United States)

    1984-12-31

    America Curitiba (BraziZ) This station, situated at the Universidade Federal do Parana, in the Instituto de Ciencias Geod6sicas under Professor C...SUL COMPOSANTE VEPTICALE ERESIL 29 40 17S 53 49 22W H 700M P 2M 0 330KM DEPOTS SEDIMENTAIRES SUk BASALTE DEPT* DE INGENIERIA RURAL-UNIV. FED. DE SANTA...PRECAMBRIENIGNEISS * UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE - DEPARTAMENTO DE FISICA TRANS WORLD TIDAL GRAVITY PROFILES P. MELCHIOR CENTRO POLITECNICO

  8. Childhood neuroblastoma masquerading as pheochromocytoma: case report

    OpenAIRE

    Moon SB

    2016-01-01

    Suk-Bae MoonDepartment of Surgery, Kangwon National University Hospital, Kangwon National School of Medicine, Kangwon National University, Chuncheon, South KoreaAbstract: Neuroblastoma is the most common extracranial solid tumor in children. Mild hypertension is a frequent symptom, presumably an effect of catecholamines that tumors release. Reported herein is the rare occurrence of severe hypertension and subsequent heart failure attributable to adrenal gland neuroblastoma. A 3-year-old boy p...

  9. Communal action of microbial cultures for Red HE3B degradation.

    Science.gov (United States)

    Patil, P S; Phugare, S S; Jadhav, S B; Jadhav, J P

    2010-09-15

    The consortium PMB11 consisting of three bacterial species, originally isolated from dye contaminated soil was identified as Bacillus odysseyi SUK3, Morganella morganii SUK5 and Proteus sp. SUK7. The consortium possessed the ability to decolorize various textile dyes as well as mixtures of dyes. PMB11 could decolorize Red HE3B (50 mg l(-1)) with 99% of decolorization within 12 h in nutrient broth, while in mineral medium it could decolorize up to 97% within 24h. Induction in the activities of various oxidative and reductive enzymes indicates the involvement of these enzymes in decolorization. Biodegradation of the dye was monitored using UV-vis spectroscopy, HPLC and FTIR analysis. The Red HE3B degradation pathway was proposed by GC-MS analysis. Various metabolites formed after the degradation were identified as 2,5-diaminobenzene 6-aminotriazine, aniline 2-sulfate, aniline 3-sulfate, 2-amino 5-chlorotriazine and naphthalene. Phytotoxicity studies revealed that metabolites formed after degradation were significantly less toxic in nature.

  10. NeighbourWoods for Better Cities

    DEFF Research Database (Denmark)

    Konijnendijk, Cecil Cornelis; Schipperijn, Jasper Jan

    This publication aims to contribute to the development af NeighbourWoods through socially-inclusive planning, design and management. It presents experiences from an international project supported by the European Commission which evaluated and developed approaches and tools to assist NeighbourWoo...

  11. International Conference on Conducting Materials (ICoCom2010) Held in Sousse, Tunisia on November 3-7, 2010

    Science.gov (United States)

    2010-11-01

    Anna Köller, (Germany) Ouahab Lahcène (France) Mustapha Majdoub (Tunisia) Daniel Ayuk Mbi Egbe (Austria) Klaus Meerholz (Germany) Yung Woo Park (Korea...Cu3O7-δ multilayers Anis-ur-Rehman (Pakistan) Synthesis and enhancement of current density in Bi(Pb)Sr( Ba )-2223 doped by rare-earth elements 16:00-16

  12. RESTAURANT INFORMATION

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Dazhaimen Seafood Garden Dining at a chain restaurant of Beijing-based Dazhaimen cater-ing group is never on the cheap side.Aimed at providing Chinese-style haute cuisine,Dazhaimen has been wooing diners with its lux-urious-looking ancient decoration sty

  13. Tumors STING adaptive antitumor immunity.

    Science.gov (United States)

    Bronte, Vincenzo

    2014-11-20

    Immunotherapy is revolutionizing the treatment of cancer patients, but the molecular basis for tumor immunogenicity is unclear. In this issue of Immunity, Deng et al. (2014) and Woo et al. (2014) provide evidence suggesting that dendritic cells detect DNA from tumor cells via the STING-mediated, cytosolic DNA sensing pathway.

  14. Higher Education and Entrepreneurial Citizenship in Singapore

    Science.gov (United States)

    Christensen, Soren

    2012-01-01

    Focusing on Singapore's "Global Schoolhouse" project, this article discusses how efforts to transform Singapore into a "world class" knowledge economy entail changes to the status of citizenship in Singapore. The project of wooing top foreign universities to Singapore is permeated with an entrepreneurial ideal of Singapore as…

  15. Ohio's Public Colleges Lure Businesses with the Promise of a Skilled Work Force

    Science.gov (United States)

    Fischer, Karin

    2008-01-01

    When NetJets, a private aviation company, announced it would keep and expand its operational headquarters in Ohio, Richard T. Santulli, chairman and chief executive, didn't give credit to tax breaks or any of the other incentives states and cities typically use to woo or retain corporations. Instead, he said the critical factor was the state's…

  16. Veneetsia mälestas kuulsat jaapanlast / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    1999-01-01

    Veneetsia 56. filmifestival. Jaapanlase Takishi Koizumi mängufilmist "Pärast vihma", mille stsenaariumi peaaegu lõpetas 1998.a. surnud Akira Kurosawa. Ka Lõuna-Korea režissööri Jang Sun Woo erootilisest mängufilmist "Valed"

  17. Sounds Exaggerate Visual Shape

    Science.gov (United States)

    Sweeny, Timothy D.; Guzman-Martinez, Emmanuel; Ortega, Laura; Grabowecky, Marcia; Suzuki, Satoru

    2012-01-01

    While perceiving speech, people see mouth shapes that are systematically associated with sounds. In particular, a vertically stretched mouth produces a /woo/ sound, whereas a horizontally stretched mouth produces a /wee/ sound. We demonstrate that hearing these speech sounds alters how we see aspect ratio, a basic visual feature that contributes…

  18. The Danish Shoulder Arthroplasty Registry

    DEFF Research Database (Denmark)

    Rasmussen, Jeppe; Jakobsen, John; Brorson, Stig

    2012-01-01

    The Danish Shoulder Arthroplasty Registry (DSR) was established in 2004. Data are reported electronically by the surgeons. Patient-reported outcome is collected 10-14 months postoperatively using the Western Ontario osteoarthritis of the shoulder index (WOOS). 2,137 primary shoulder arthroplastie...

  19. Collaborative Platform for DFM

    Science.gov (United States)

    2007-12-20

    pleasure of working with or learning from Alejandro De La Fuente, Chung Sung, Zheng Guo, Liang-Teck Pang, Paul Friedberg, Louis Alarcon, Qingguo Liu, Yu...simulation” SPIE, vol.5756, no.38, 2005 24 Ortolland, C. Orain, S. Rosa , J. Morin, P. Arnaud, F. Woo, M. Poncet, A. Stolk, P

  20. Report of the Hydrographic Service Royal Australian Navy for the Year Ended 30th June 1990. Issue Number 26

    Science.gov (United States)

    1990-06-30

    dato Wo~o. housd ft tito lhirms moiwoon j~?4 ourno. tiod it cnpobiv or tniottrly 1l-lasng cltrt*. A* writ ms produ~cing frtvrigA mid isivi g cltnris...The Naval Weather Centro watt retitled the ’Noval Weather and Oceanographic Centre* iNWOOa in early 1990. to better rvflect. itsi it ceased

  1. The Global Reach of Chinese Soft Power: China’s Rise and America’s Decline?

    Science.gov (United States)

    2007-09-01

    exposure into China’s retail and cultural markets. Among those wooed by the Chinese style is National Basketball Association’s Houston Rockets, Leslie...in fear of instability and refugee flows in the northeast where protest rates are the highest. China’s inability to free up exchange rates due to fear

  2. NeighbourWoods for Better Cities

    DEFF Research Database (Denmark)

    Konijnendijk, Cecil Cornelis; Schipperijn, Jasper Jan

    This publication aims to contribute to the development af NeighbourWoods through socially-inclusive planning, design and management. It presents experiences from an international project supported by the European Commission which evaluated and developed approaches and tools to assist NeighbourWoo......Wood planners, designers, and managers....

  3. Experimental Study on Dry Torrefaction of Beech Wood

    NARCIS (Netherlands)

    Gucho, E.M.; Shahzad, K.; Bramer, E.A.; Akhtar, N.A.; Brem, G.

    2015-01-01

    Torrefaction is a thermochemical pre-treatment process for upgrading the properties of biomass to resemble those of fossil fuels such as coal. Biomass properties of particular interest are chemical composition, physical property and combustion characteristics. In this work, torrefaction of beech woo

  4. Higher Education and Entrepreneurial Citizenship in Singapore

    Science.gov (United States)

    Christensen, Soren

    2012-01-01

    Focusing on Singapore's "Global Schoolhouse" project, this article discusses how efforts to transform Singapore into a "world class" knowledge economy entail changes to the status of citizenship in Singapore. The project of wooing top foreign universities to Singapore is permeated with an entrepreneurial ideal of Singapore as…

  5. Artificial intelligence expert systems with neural network machine learning may assist decision-making for extractions in orthodontic treatment planning.

    Science.gov (United States)

    Takada, Kenji

    2016-09-01

    New approach for the diagnosis of extractions with neural network machine learning. Seok-Ki Jung and Tae-Woo Kim. Am J Orthod Dentofacial Orthop 2016;149:127-33. Not reported. Mathematical modeling. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Resonance Fluorescence of Many Interacting Adatoms at a Metal Surface.

    Science.gov (United States)

    1983-06-01

    a series of experiments in which the fluores - cence of an excited atom or molecule at a fixed distance from a metal surface (gold, silver and cooper...Theodore E. Madey Surface Chemistry Section Dr. Chia -wel Woo Department of Commerce Department of Physics National Bureau of Standards Northwestern

  7. Resonance Fluorescence of a Two-Level Atom Near a Metal Surface. II. Case of a Strong Driving Field,

    Science.gov (United States)

    1984-02-01

    displayed in Figures 4 and 5. While the height H, and integrated power P+ of the fluores - cence component (P+ is the area under the curve for the...Massachusetts 02139 Dr. Chia -wei Woo Dr. J. M. White Department of Physics Department of Chemistry Northwestern University University of Texas

  8. Higher Education and Entrepreneurial Citizenship in Singapore

    Science.gov (United States)

    Christensen, Soren

    2012-01-01

    Focusing on Singapore's "Global Schoolhouse" project, this article discusses how efforts to transform Singapore into a "world class" knowledge economy entail changes to the status of citizenship in Singapore. The project of wooing top foreign universities to Singapore is permeated with an entrepreneurial ideal of Singapore…

  9. Muusikauudiseid maailmast / Ia Remmel

    Index Scriptorium Estoniae

    Remmel, Ia, 1965-

    2016-01-01

    Lühisõnumeid maailmast: Suri Einojuhani Rautavaara. ECHO Klassiku 2017. aasta preemia saajad selgunud. Bachi haruldane käsikiri oksjonil. "Operalia 2016" võitjad on Keon-Woo Kim ja Elsa Dreisig. Shakespeare'i Globe asutas oma plaadimärgi. Sydney konkursi vitis vene pianist Andrei Gugnin. Noorel rootsi viiuldajal leping Deutsche Grammophoniga

  10. Outcome, revision rate and indication for revision following resurfacing hemiarthroplasty for osteoarthritis of the shoulder: 837 operations reported to the Danish Shoulder Arthroplasty Registry.

    Science.gov (United States)

    Rasmussen, J V; Polk, A; Sorensen, A K; Olsen, B S; Brorson, S

    2014-04-01

    In this study, we evaluated patient-reported outcomes, the rate of revision and the indications for revision following resurfacing hemiarthroplasty of the shoulder in patients with osteoarthritis. All patients with osteoarthritis who underwent primary resurfacing hemiarthroplasty and reported to the Danish Shoulder Arthroplasty Registry (DSR), between January 2006 and December 2010 were included. There were 772 patients (837 arthroplasties) in the study. The Western Ontario Osteoarthritis of the Shoulder (WOOS) index was used to evaluate patient-reported outcome 12 months (10 to 14) post-operatively. The rates of revision were calculated from the revisions reported to the DSR up to December 2011 and by checking deaths with the Danish National Register of Persons. A complete questionnaire was returned by 688 patients (82.2%). The mean WOOS was 67 (0 to 100). A total of 63 hemiarthroplasties (7.5%) required revision; the cumulative five-year rate of revision was 9.9%. Patients aged < 55 years had a statistically significant inferior WOOS score, which exceeded the minimal clinically important difference, compared with older patients (mean difference 14.2 (8.8; 95% CI 19.6; p < 0.001), but with no increased risk of revision. There was no significant difference in the mean WOOS or the risk of revision between designs of resurfacing hemiarthroplasty.

  11. Muusikauudiseid maailmast / Ia Remmel

    Index Scriptorium Estoniae

    Remmel, Ia, 1965-

    2016-01-01

    Lühisõnumeid maailmast: Suri Einojuhani Rautavaara. ECHO Klassiku 2017. aasta preemia saajad selgunud. Bachi haruldane käsikiri oksjonil. "Operalia 2016" võitjad on Keon-Woo Kim ja Elsa Dreisig. Shakespeare'i Globe asutas oma plaadimärgi. Sydney konkursi vitis vene pianist Andrei Gugnin. Noorel rootsi viiuldajal leping Deutsche Grammophoniga

  12. Integrated DoD Voice and Data Networks and Ground Packet Radio Technology

    Science.gov (United States)

    1976-08-01

    also been well-studied. Several algorithms are found in the litera- ture [CHOU, 1973], ( ESAU , 1966], [WOO, 1973]. Typically, the algorithms solve...Data Communications Symposium, St. Peters- burg, Florida, November 13-15, 1973. ( ESAU , 1966] Esau , L.R. and K.C. Williams, "On Teleproces- sing

  13. Battle of the Brands

    Institute of Scientific and Technical Information of China (English)

    FLORA BAGENAL

    2008-01-01

    @@ Mid-range retailers are flooding into China in an attempt to woo the country's new and growing class of consumers - but success is by no means guaranteed Meet Xiao Wei. Her beige handbag is a Stella McCartney knock-off but her Converse trainers are real, bought from a boutique shoe shop in west Beijing.

  14. a general review and performance evaluation of multi a general ...

    African Journals Online (AJOL)

    eobe

    E-mail address: crescent.omeje@uniport.edu.ng. ABSTRACT. This paper ... technology and the commercial availability of high ... Multi-level converter technology began in 1960 with ...... Gun-Woo Moon, “A Three Phase Three-Level PWM.

  15. Disease: H01337 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available o PC, Teng JL, Leung KW, Wong MK, Lau SK Laribacter hongkongensis gen. nov., sp. nov., a novel gram-negative...Microbiol 39:4227-32 (2001) PMID:19283063 (description) Woo PC, Lau SK, Tse H, Teng JL, Curreem SO, Tsang AK, Fan RY, Wong

  16. Iron content in forage sorghum (Sorghum bicolor (L.) Moench ...

    African Journals Online (AJOL)

    Administrator

    2011-09-12

    Sep 12, 2011 ... Byung Hoon Park1, Deok Jung Kim1, Kun Woo Park1, Mun Soo ... Jun Lee1, Yong Min Lee1, In Sub Choi1, Hyo Jeong Lee1, Jae Won .... already described in previous reports (Chang et al., 1993, Kim et ..... environment.

  17. The Best Investment for the Air Superiority Fighter of the Year 2000: The Aircraft, Its Weapon System or Its Armament?

    Science.gov (United States)

    1986-05-01

    Tactical Aircraft Division, 21 and 22 April 1986. 5. Study made in 1985 for a seminar of the Air War College by Colonel Bodie Bodenheim , USAF, and the...Magazine, January 1986, pp. 38-45. Ulsamer, Edgar , *Hard Calls on Tactical Technology.- Air Force Magazine, April 1986, pp. 58-64. A 0 _4 4.I _woo= ,DŔ

  18. Veneetsia mälestas kuulsat jaapanlast / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    1999-01-01

    Veneetsia 56. filmifestival. Jaapanlase Takishi Koizumi mängufilmist "Pärast vihma", mille stsenaariumi peaaegu lõpetas 1998.a. surnud Akira Kurosawa. Ka Lõuna-Korea režissööri Jang Sun Woo erootilisest mängufilmist "Valed"

  19. Epoxidation of soybean oil catalyzed by peroxo phosphotungstic acid supported on modified halloysite nanotubes

    Science.gov (United States)

    Jiang, Junqing; Zhang, Yanwu; Yan, Liwei; Jiang, Pingkai

    2012-06-01

    {PO4[W(O)(O2)2]4}3- was supported onto modified halloysite nanotubes (HNTs) to prepare heterogeneous catalysts and these catalysts were applied in epoxidation of soybean oil. To enhance the cohesive force between {PO4[W(O)(O2)2]4}3- and HNTs, quaternary amino groups were anchored onto HNTs through silylation of N-(2-aminoethyl)-3-aminopropyl trimethoxysilane and alkylation of amino groups. Further {PO4[W(O)(O2)2]4}3- was supported onto HNTs by ion exchange. The heterogeneous catalysts were characterized by FTIR, TGA, XRF and TEM-EDS. Then the catalytic behaviour to epoxidation of soybean oil was studied in detail. The results show that the introduction of phase transfer agent during preparation of the catalysts is very effective to improve catalytic activity and mechanical agitation combining with ultrasonic agitation is the best agitation way. The catalytic reactivity increased as reaction time increased. Moreover, the catalysts can be easily recovered from the reaction system by centrifugation as deposit and recycled three times without obviously decreasing the catalytic activity. Through re-exchange of {PO4[W(O)(O2)2]4}3-, the heterogeneous catalyst can be regenerated without catalytic activity loss.

  20. High Rate Performing Li-ion Battery

    Science.gov (United States)

    2015-02-09

    permeable to lithium ions and efficient in transferring the electrons into/from the LVP surface to the corresponding current collector. a) b) c) d) e...PO4)3/C for High Rate Lithium-ion Battery Applications”, Lee Hwang Sheng, Nail Suleimanov, Vishwanathan Ramar, Mangayarkarasi Murugan, Kuppan

  1. An Integrated Decision Model for Evaluating Educational Web Sites from the Fuzzy Subjective and Objective Perspectives

    Science.gov (United States)

    Huang, Tony Cheng-Kui; Huang, Chih-Hong

    2010-01-01

    With advances in information and network technologies, lots of data have been digitized to reveal information for users by the construction of Web sites. Unfortunately, they are both overloading and overlapping in Internet so that users cannot distinguish their quality. To address this issue in education, Hwang, Huang, and Tseng proposed a group…

  2. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  3. Beyond Authoritarian Personality: The Culture-Inclusive Theory of Chinese Authoritarian Orientation.

    Science.gov (United States)

    Chien, Chin-Lung

    2016-01-01

    In a dyad interaction, respecting and obeying those with high status (authority) is highly valued in Chinese societies. Regarding explicit behaviors, Chinese people usually show respect to and obey authority, which we call authoritarian orientation. Previous literature has indicated that Chinese people have a high degree of authoritarian personality, which was considered a national character. However, under Confucian relationalism (Hwang, 2012a), authoritarian orientation is basically an ethical issue, and thus, should not be reduced to the contention of authoritarian personality. Based on Yang's (1993) indigenous conceptualization, Chien (2013) took an emic bottom-up approach to construct an indigenous model of Chinese authoritarian orientation; it represents a "culture-inclusive theory." However, Chien's model lacks the role of agency or intentionality. To resolve this issue and to achieve the epistemological goal of indigenous psychology (that is, "one mind, many mentalities"), this paper took the "cultural system approach" (Hwang, 2015b) to construct a culture-inclusive theory of authoritarian orientation in order to represent the universal mind of human beings as well as the mentalities of people in a particular culture. Two theories that reflect the universal mind, the "Face and Favor model" (Hwang, 1987) and the "Mandala Model of Self" (Hwang, 2011a,c), were used as analytical frameworks for interpreting Chien's original model. The process of constructing the culture-inclusive theory of authoritarian orientation may represent a paradigm for the construction of indigenous culture-inclusive theories while inspiring further development. Some future research directions are proposed herein.

  4. Home-based telerehabilitation is not inferior to a centre-based program in patients with chronic heart failure: a randomised trial

    Directory of Open Access Journals (Sweden)

    Rita Hwang

    2017-04-01

    Trial registration: ACTRN12613000390785. [Hwang R, Bruning J, Morris NR, Mandrusiak A, Russell T (2017 Home-based telerehabilitation is not inferior to a centre-based program in patients with chronic heart failure: a randomised trial. Journal of Physiotherapy 63: 101–107

  5. Single-molecule choreography between telomere proteins and G quadruplexes.

    Science.gov (United States)

    Hopfner, Karl-Peter

    2014-06-10

    Telomeric DNA binds proteins to protect chromosome ends, but it also adopts G quadruplex (GQ) structures. Two new studies by Hwang and colleagues (in this issue of Structure) and Ray and colleagues (published elsewhere) use single molecule imaging to reveal how GQs affect the binding of different telomere associated proteins. The data suggest that GQs play important roles in regulating accessibility of telomeres.

  6. The Fourteenth International Meeting on Time-Resolved Vibrational Spectroscopy (TRVS XIV)

    Science.gov (United States)

    2010-02-03

    617-253-7030 e-mail: tokmakof@MIT.edu Project Manager: Dr. Michael Berman Grant Number: FA9550-09-1-0473 March 2, 2010...Hoffmann, Janos Hebling, Harold Y. Hwang, THz-pump/THz-probe nonlinear spectroscopy Ka-Lo Yeh, Keith A. Nelson, MIT 11:30 AM C Tomonori Nomoto and

  7. 他尊感情と自尊感情が自己表現に与える影響

    OpenAIRE

    石川, 満佐育; 石隈, 利紀; 濱口, 佳和

    2005-01-01

    This study was conducted to investigate the effects of other-esteem and self-esteem on self-expression. Study 1, drawing on the concept of other-esteem advocated by Hwang (2000), developed a scale of other-esteem consists ...

  8. Issues in Analyzing Alignment of Language Arts Common Core Standards with State Standards

    Science.gov (United States)

    Beach, Richard W.

    2011-01-01

    This commentary on Porter, McMaken, Hwang, and Yang's "Common Core Standards: The New U.S. Intended Curriculum," which finds a lack of alignment between the Common Core State Standards and state standards and assessments, suggests possible reasons for the lack of alignment. It also offers possible reasons for Porter et al.'s finding of a lack of…

  9. Assessing the Quality of the Common Core State Standards for Mathematics

    Science.gov (United States)

    Cobb, Paul; Jackson, Kara

    2011-01-01

    The authors comment on Porter, McMaken, Hwang, and Yang's recent analysis of the Common Core State Standards for Mathematics by critiquing their measures of the focus of the standards and the absence of an assessment of coherence. The authors then consider whether the standards are an improvement over most state mathematics standards by discussing…

  10. Computational and Experimental Investigation of Contaminant Plume Response to DNAPL Source Zone Architecture and Depletion in Porous and Fractured Media

    Science.gov (United States)

    2013-09-01

    estimation of the chlorinated ethylene and chlorinated acetylene reduction model by Zero-Valent Iron, in preparation. Hwang, H.-T., E. A. Sudicky, W. A...available hydraulic head and concentration data as well as signatures of stable isotope data of chlorinated solvents; (4) to conduct laboratory experiments...analytical techniques to analyze compound-specific hydrogen of chlorinated Solvents: Introduction

  11. Complex Materials and Devices

    Science.gov (United States)

    2013-03-07

    Disruptive Basic Research Areas” – Metamaterials and Plasmonics – Quantum Information Science – Cognitive Neuroscience – Nanoscience and...Sayir, Fuller) Bio-Sensing of Magnetic Fields (Larkin, Bradshaw, Curcic, DeLong 2D Materials & Devices Beyond Graphene (Hwang, Pomrenke, Harrison

  12. Spontaneous Subconjunctival Abscess Because of Haemophilus influenzae

    Science.gov (United States)

    2010-07-01

    REFERENCES 1. Hedlin P, Blondeau JM. Comparative minimal inhibitory and mutant prevention drug concentrations of four fluoroquinolones against ocular... fluoroquinolones . Cornea. 2007;26:238 240. 18. Maskin SL. Infectious scleritis after a diabetic foot ulcer. Am J Ophthalmol. 1993;115:254 255. 19. Hwang

  13. InAs1-xSbx Alloys with Native Llattice Parameters Grown on Compositionally Graded Buffers: Structural and Optical Properties

    Science.gov (United States)

    2013-08-15

    Hwang, Eun Jeor Chun Hum Cho of Metai/PVDF-tr place in the Best I paper "Carbon Na and Management · their paper entitlec Semiconductor ," r...This issue inc selected after the , M. Stanacevic, A. V. :les, W. K. Chan, and Z. on of InP scintillation ," sited," IEEE J. Selected I Journal of

  14. Exploiter la Littérature en Classe du Fle: Allah N'est Pas Obligé D ...

    African Journals Online (AJOL)

    Prof

    jour des pratiques de classe des enseignants de français. ... reflètent une évolution d'une pédagogie de l'avoir fondée sur la transmission d'un savoir et ... nouvelles habitudes influencent le choix de leurs lectures (Hwang 55). Les pratiques ...

  15. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  16. Reference: ABREATCONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ABREATCONSENSUS Choi HI, Park HJ, Park JH, Kim S, Im MY, Seo HH, Kim YW, Hwang I, Kim SY.... of Abscisic Acid-Responsive Gene Expression, and Modulates Its Activity. Plant Physiol. 139: 1750-1761(2005) PubMed: 16299177 ...

  17. Design Equations and Criteria of Orthotropic Composite Panels

    Science.gov (United States)

    2013-05-01

    3850 (TIC), 60 ( SharePoint ), 65, 652 (Hwang, Scott, Taylor), 654 (Wells), 655, 655 (Coffin, Fick, Hart, B. Jones, Noland, Pohlit, Udinski... angular orientation; see Figure A-1. Micro-mechanics analysis can be used to predict the behavior of the laminate. Equivalent properties can be

  18. EFL College Students' Attitudes towards Mobile Learning

    Science.gov (United States)

    Dashti, Fatimah A.; Aldashti, Abdulmohsen A.

    2015-01-01

    Recently, cell phones have received much attention in the context of EFL/ESL learning. Mobile learning, in general, and distant learning, in particular, in educational contexts has been approached by educationalist all over the world (Hwang & Chang, 2011). Presently, countries pay ample attention to mobile learning in education. Despite the…

  19. Harnessing Functional Genomics to Reverse Chemoresistance in Breast Cancer

    Science.gov (United States)

    2008-10-01

    tin g Cytokinesis Phagocytosis GLUT4 Exocyst RALB NF B IRF3 Others TBK1 Translational control As sem bly an d mo bil iza tio n En do cy to sis Innate...Inoue, M., Chang, L., Hwang, J., Chiang, S. H. & Saltiel, A. R. The exocyst complex is required for targeting of Glut4 to the plasma membrane by

  20. Overcoming Resistance of Prostate Cancer to TRAIL - Mediated Apoptosis

    Science.gov (United States)

    2005-12-01

    Palombella VJ, Sausville EA, Joahnson J, Destree A, Lazarus DD, Maas J, Pien CS, Prakash S and Elliott PJ. (1999). Cancer Res., 59, 2615–2622. An WG, Hwang S...assistance of Sarah Winbourn. REFERENCES 1. Wiley, S. R., Schooley, K., Smolak, P. J., Din, W. S., Huang, C. P., Nicholl, J. K., Sutherland, G. R

  1. An Integrated Decision Model for Evaluating Educational Web Sites from the Fuzzy Subjective and Objective Perspectives

    Science.gov (United States)

    Huang, Tony Cheng-Kui; Huang, Chih-Hong

    2010-01-01

    With advances in information and network technologies, lots of data have been digitized to reveal information for users by the construction of Web sites. Unfortunately, they are both overloading and overlapping in Internet so that users cannot distinguish their quality. To address this issue in education, Hwang, Huang, and Tseng proposed a group…

  2. Antimicrobial Decapeptide KSL-W Attenuates Candida albicans Virulence by Modulating Its Effects on Toll-Like Receptor, Human Beta-Defensin, and Cytokine Expression by Engineered human Oral Mucosa

    Science.gov (United States)

    2011-02-02

    ability to activate the innate immunity exhibited by the targeted epithelial cells. Overall results suggest that KSL-W may have antipathogenic properties ...Hwang D, Yang M, Jeon R, et al. Garlic (Allium sativum) extract inhibits lipopolysaccharide-induced Toll-like receptor 4 dimerization. Biosci Biotechnol

  3. The rearrangement process in a two-stage broadcast switching network

    DEFF Research Database (Denmark)

    Jacobsen, Søren B.

    1988-01-01

    The rearrangement process in the two-stage broadcast switching network presented by F.K. Hwang and G.W. Richards (ibid., vol.COM-33, no.10, p.1025-1035, Oct. 1985) is considered. By defining a certain function it is possible to calculate an upper bound on the number of connections to be moved...

  4. Correction: Dye adsorption mechanisms in TiO2 films, and their effects on the photodynamic and photovoltaic properties in dye-sensitized solar cells.

    Science.gov (United States)

    Hwang, Kyung-Jun; Shim, Wang-Geun; Kim, Dajung; An, Jongdeok; Im, Chan; Kim, Youngjin; Kim, Gunwoo; Choi, Chulmin; Kang, Sang Ook; Cho, Dae Won

    2016-02-21

    Correction for 'Dye adsorption mechanisms in TiO2 films, and their effects on the photodynamic and photovoltaic properties in dye-sensitized solar cells' by Kyung-Jun Hwang et al., Phys. Chem. Chem. Phys., 2015, 17, 21974-21981.

  5. 他尊感情と自尊感情が自己表現に与える影響

    OpenAIRE

    石川, 満佐育; 石隈, 利紀; 濱口, 佳和

    2005-01-01

    This study was conducted to investigate the effects of other-esteem and self-esteem on self-expression. Study 1, drawing on the concept of other-esteem advocated by Hwang (2000), developed a scale of other-esteem consists ...

  6. Outcome, revision rate and indication for revision following resurfacing hemiarthroplasty for osteoarthritis of the shoulder

    DEFF Research Database (Denmark)

    Rasmussen, J V; Polk, A; Sorensen, A K

    2014-01-01

    In this study, we evaluated patient-reported outcomes, the rate of revision and the indications for revision following resurfacing hemiarthroplasty of the shoulder in patients with osteoarthritis. All patients with osteoarthritis who underwent primary resurfacing hemiarthroplasty and reported...... to the Danish Shoulder Arthroplasty Registry (DSR), between January 2006 and December 2010 were included. There were 772 patients (837 arthroplasties) in the study. The Western Ontario Osteoarthritis of the Shoulder (WOOS) index was used to evaluate patient-reported outcome 12 months (10 to 14) post......-operatively. The rates of revision were calculated from the revisions reported to the DSR up to December 2011 and by checking deaths with the Danish National Register of Persons. A complete questionnaire was returned by 688 patients (82.2%). The mean WOOS was 67 (0 to 100). A total of 63 hemiarthroplasties (7...

  7. Evaporation of a Thickened Agent Simulant from Oak and Hickory Leaves

    Science.gov (United States)

    1990-12-01

    330M0 2.53934 .404272 3.697723 .59573 2.45098 .394869 .3793 1.34055 360.0 2.33976 .376951 3.86T303 . 62305 2.25244 .362883 .4138 1.46242 390.0 2.19000...RSTE 09’ 2 MH OR9PS DEPO-31’W ON LERF SURFACE FOR 3 HR AT 561 .6 F AND 42% RH APPENDIX IK 3S56 K ESTIMATE, OF AVERAC!.,’ El.,’ iECS ANt SUk oJP SQUARES

  8. WebBee: A Platform for Secure Coordination and Communication in Crisis Scenarios

    Science.gov (United States)

    2008-04-16

    07) 0.42 Patrick Turley (1/28/07 - 5/31/08) 0.50 John Umbaugh (9/30/07 - 6/30/08) 0.25 Krian Upatkoon (9/1/05 - 12/21/06) 1.00 Byung Suk Yang (7/1...graduated during this period: 5.00...... Names of Personnel receiving masters degrees NAME Mathew England John Umbaugh Todd Hopfinger Jeffrey Powers...4Total Number: Names of other research staff PERCENT_SUPPORTEDNAME Melinda Larocca (10/23/06 - 12/31/07) 0.10 No Beverly Monaghan (9/19/05 - 9/30/06

  9. Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2011-01-01

    Muusikasõnumeid maailmast: 14. Tšaikovski nimelisest konkursist. Daniel Barenboim tõstetakse rüütliseisusesse. Orkestrist I, Culture Orchestra. Charles Dutoit plaanib luua Lõuna- ja Põhja-Koread ühendava orkestri. Lahkus Josef Suk. Seiji Ozawa pälvis Praemium Imperiale auhinna. Cardiffi lauljate konkursi võitis Valentina Nafornita. Lahkus Nikolai Petrov. Venetsueelas lööb laineid noor dirigent Jose Omar Davila. "Jazzkaare" täht Brass Jaw sai Suurbritannias suure tunnustuse osaliseks. Põhjamaade Nõukogu muusikaauhinna teenis Mats Gustafsson. Black Eyed Peas paneb pillid kotti. Kuuba kitarrist Manuel Galban surnud. Eesti on Tšehhi jazziraadio fookuses

  10. ŠIAULIŲ UNIVERSITETO ANTRO KURSO STUDENTŲ GYVENSENOS ASPEKTAI

    OpenAIRE

    2010-01-01

    Bakalauro darbe nagrinėjami akademinio jaunimo gyvensenos aspektai. Sveikos gyvensenos elementai yra sveika mityba, grūdinimąsis, fizinis aktyvumas, tinkamas poilsis, žalingų įpročių atsisakymas ir kita. Šiame darbe nagrinėjami keli, didžiausią Lietuvos ir užsienio mokslininkų susidomėjimą sukėlę, gyvensenos aspektai. Suformuluota hipotezė, kad akademinis jaunimas nėra pati sveikiausia visuomenės dalis. Gyvensenos analizė turėtų patvirtinti jaunimo sveikatos problemas, susijusias su žali...

  11. Warrant Officer Senior Course WOSC Evaluation.

    Science.gov (United States)

    1981-07-01

    2 Masterworks of English Literature 2 All classes observed were well conducted. Instructors displayed adequate preparation, competence, and interest...Tax Accounting I 1 Visual Arts 1 Masturworks of English Literature 2 Policy & Decision Making 1 Cor-p-)ration Finance I imf). r if Students Enrolled...the problem situations. H-17 i’EST OUTLINE P(1[ TRAINING TESI ITEM SUkBJECT: COtIltII:Vd and Staff rIME NUMBERS NR, ESIRED 1EARN IN , HOURS TEST FORM

  12. Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2011-01-01

    Muusikasõnumeid maailmast: 14. Tšaikovski nimelisest konkursist. Daniel Barenboim tõstetakse rüütliseisusesse. Orkestrist I, Culture Orchestra. Charles Dutoit plaanib luua Lõuna- ja Põhja-Koread ühendava orkestri. Lahkus Josef Suk. Seiji Ozawa pälvis Praemium Imperiale auhinna. Cardiffi lauljate konkursi võitis Valentina Nafornita. Lahkus Nikolai Petrov. Venetsueelas lööb laineid noor dirigent Jose Omar Davila. "Jazzkaare" täht Brass Jaw sai Suurbritannias suure tunnustuse osaliseks. Põhjamaade Nõukogu muusikaauhinna teenis Mats Gustafsson. Black Eyed Peas paneb pillid kotti. Kuuba kitarrist Manuel Galban surnud. Eesti on Tšehhi jazziraadio fookuses

  13. Marginalijos Žibunto Mikšio Šiaulių universiteto bibliotekai dovanotose knygose

    OpenAIRE

    Markulytė, Greta

    2013-01-01

    Marginalijos – svarbus, informatyvus knygos elementas, atskleidžiantis ne tik marginalijų ypatybes, sukūrimo laiką, vietą, bet ir jų kūrėjo visai kitą asmenybės pusę. Bakalauro darbe aptariama marginalijų samprata, tyrimų kryptys ir vienas iš sudėtingiausių aspektų – marginalijų klasifikacija. Darbe analizuojamos Ž. Mikšio ŠU bibliotekai dovanotų knygų marginalijos, kurios sudaro tokias grupes: paprastosios arba bendrosios marginalijos, taisančiosios marginalijos ir papildoma informac...

  14. Quantum Confined Semiconductors - In-House Interim Research

    Science.gov (United States)

    2013-04-01

    Laboratory, Materials & Manufacturing Directorate, Wright Patterson AFB, OH 45433-7707, USA blnstituto de Ciencias Fisicas , Universidad Nacional Aut6noma...111is work was supported by the Ai1· Force Office of Scientific Research (AFRU RS E, Dr. Kitt Reinhardt). • Also with lnstituto de Ciencias Fisicas ...2007). [10) Coe, S., Woo, W. K., Bawendi, M and Bulovic, V., "Electroluminescence from sing le monolayers of nanocrystals in molecular organic devices

  15. Analysis of an Emitter Location Algorithm for use in ESM Systems

    Science.gov (United States)

    2005-09-01

    2280 AA Rijswijk PROGRAMMA PROJECT www.tno.ni Programmabegeleider Projectbegeleider LtKoI. J.P. Strijker, CTL/A3O/HSEOV LtKoI. J.P. Strijker, CTL/ AJO ...ONGERUBRICEERD Distributionlist Distributie rapport 1 . SC-WOO 2. HWO- KLu 3. KLu/ AJO /HSEOV, t.a.v. LtKol J.P. Strijker 4. TNO Defensie en Veiligheid

  16. Micro/nano-particles and Cells: Manipulation, Transport, and Self-assembly

    Science.gov (United States)

    2014-10-23

    doi: 10.1103/PhysRevLett.107.087206 Aaron Chen, Tom Byvank, Woo-Jin Chang, Atul Bharde, Greg Vieira, Brandon L. Miller, Jeffrey J. Chalmers, Rashid ...Duarte Guevara, Brian Dorvel, Bobby Reddy, Amelie Eriksson Karlstrom, Yu Chen, Hongmiao Ji, Yu Chen, Ratnasingham Sooryakumar, Rashid Bashir. Ultra...Sooryakumar,and Rashid Bashir. Ultra-Localized Single Cell Lysis Using Silicon Nanowires, Lab on a Chip (08 2012) Aaron Chen, Tom Byvank, Gregory B. Vieira

  17. Using the CPU and GPU for real-time video enhancement on a mobile computer

    CSIR Research Space (South Africa)

    Bachoo, AK

    2010-09-01

    Full Text Available Language (2nd Edition), Addison- Wesley Professional, 2006. [6] D. Shreiner, M. Woo, J. Neider, and T. Davis, OpenGL Programming Guide, Addison-Wesley Professional, 2007. [7] SM Pizer, EP Amburn, JD Austin, R Cromartie, A Geselowitz, T Greer, BM ter... computer,? in The Twentieth Annual Symposium of the Pattern Recognition Association of South Africa (PRASA), 2009. [11] RC Gonzalez and RE Woods, Digital image processing, Addison-Wesley Publishing Company, 2002. ...

  18. The global reach of Chinese soft power China's rise and America's decline?

    OpenAIRE

    Hoey, James H.

    2007-01-01

    Over the past decade, China has downplayed its hard power, instead focusing on a strategy to build its soft power. Emerging from a shell of defensive diplomacy dating back decades, China suddenly has engaged the world, wooing friends with a subtle, softer approach to make gains as America's popularity has plummeted. In Africa, newly popular China is winning oil and gas deals; in Latin America, China is signing strategic partnerships; in the Philippines, Chinese films are making inroads agains...

  19. Characterization of an infectious pancreatic necrosis virus from rainbow trout fry(Onhorhynchus mykiss) in West Ukraine

    Institute of Scientific and Technical Information of China (English)

    Yuriy; P; Rud; Maria; I; Maistrenko; Leonid; P; Buchatskiy

    2015-01-01

    <正>Dear Editor,Aquatic birnaviruses are a group within the family Birnaviridae that comprise isolates from fish and shellfish from both fresh-and seawater(Woo and Bruno,1999).Members of the family Birnaviridae are icosahedral viruses approximately 60 nm in diameter composed of five polypeptides and two segments of double-stranded RNA(Dixon et al.,2008).In this report,an aquatic birnavirus was isolated from rainbow trout fry,Onhorhynchus myki-

  20. Boomers versus Millennials: Online Media Influence on Media Performance and Candidate Evaluations

    OpenAIRE

    Terri Towner; Caroline Lego Munoz

    2016-01-01

    Facebook posts, YouTube videos, tweets and wooing political bloggers have become standard practice in marketing political campaigns. Research has demonstrated the effect of new media on a host of politically-related behavior, including political participation, knowledge acquisition, group formation and self-efficacy. Yet, issues related to media trust, media performance and candidate evaluations have not been fully explored. In addition, much of the political marketing research looks exclusiv...

  1. Electrochemical Interfaces and Electrode Processes.

    Science.gov (United States)

    1984-08-15

    and F. Will, The Electrochemical Society , Princeton, NJ, 1977, p. 172. 7. W. E. O’Grady, M. Woo, P. Hagans and E. Yeager, J. Vac. Sci. Technol. 14 (1977...T. Chen and E. Yeager, in Passivity of Metals, eds. R. P. Frankenthal and J. Kruger, The Electrochemical Society , Princeton, NJ, 1978, p. 546-563...Eldridge, R. Hoffman, R. Hehemann and E. Yeager, Proc. Symposium on Corrosion, R. Frankenthal and J. Kruger, eds., The Electrochemical Society , Pennington

  2. Strongly Interacting Fermi Gases in Two Dimensions

    Science.gov (United States)

    2012-07-17

    Svistunov, M. Ku, A. Sommer, L. W. Cheuk, A. Schirotzek, M. W. Zwierlein Feynman diagrams versus Fermi-gas Feynman emulator Nature Physics 8... Feynman emulator. Nature Physics 8, 366 (2012) 4. Jee Woo Park, Cheng-Hsun Wu, Ibon Santiago, Tobias G. Tiecke, Peyman Ahmadi, Martin W. Zwierlein...chapters 7. M. Randeria, W. Zwerger, and M. Zwierlein. The BEC-BCS Crossover and the Unitary Fermi Gas. Lecture Notes in Physics , Volume 836, edited by

  3. LAMDA at TREC CDS track 2015: Clinical Decision Support Track

    Science.gov (United States)

    2015-11-20

    biomedical literature retrieval for clinical cases: a survey of the TREC 2014 CDS track," Information Retrieval Journal , pp. 1-36. [2] M. S. Simpson and...LAMDA at TREC CDS track 2015 Clinical Decision Support Track Moon Soo Cha, Woo-Jin Han, Garam Lee, Minsung Kim, Kyung-Ah Sohn* Department of...Information and Computer Engineering Ajou University Suwon, Republic of Korea (ckanstnzja; data; piratekl; kimmsql; kasohn)@ajou.ac.kr Abstract

  4. Health system creates brand identity with clinical paths, outcomes data, report cards.

    Science.gov (United States)

    1998-03-01

    Using data to woo consumers: A four-hospital system in southern California is aggressively capturing and touting systemwide data in an effort to directly reach consumers with the message that health care is of consistently high quality across the system. A systemwide report card doesn't even break the data out by hospital but instead is an attempt to "brand" health care. Here's the story, plus some unique data charts from the consumer report card.

  5. U.S. Security Policy in Asia after Korean Unification

    Science.gov (United States)

    1997-12-01

    Korean War and the signing of the mutual defense treaty, the United States has maintained forward-deployed forces in Korea . Today the United States has...30 American forward-deployed forces have become less important to the defense of Korea as the capabilities of the South Korean military have...Environment for a United Korea ", The Korean Journal of Defense Analysis Vol. VIII No. 1 (Summer 1996): 81- 82. 81 Amy Woo, "East Asia: China Treads Korean

  6. A Continuum Mechanical Approach to Geodesics in Shape Space

    Science.gov (United States)

    2010-01-01

    A CONTINUUM MECHANICAL APPROACH TO GEODESICS IN SHAPE SPACE By Benedikt Wirth Leah Bar Martin Rumpf and Guillermo Sapiro IMA Preprint Series # 2295...Benedikt Wirth† Leah Bar‡ Martin Rumpf† Guillermo Sapiro‡ †Institute for Numerical Simulation, University of Bonn, Germany ‡Department of Electrical and...mean curvature flow equation. Calc. Var., 3:253–271, 1995. [30] Siddharth Manay, Daniel Cremers , Byung-Woo Hong, Anthony J. Yezzi, and Stefano Soatto

  7. A Standard Monetary Model and the Variability of the Deutschemark-DollarExchange Rate

    OpenAIRE

    Kenneth D. West

    1986-01-01

    This paper uses a novel teat to see whether the Herse (1985) and Woo (1985) models are consistent with the variability of the deutschemark - dollar exchange rate 1974-1984. The answer, perhaps surprisingly, is yes. Both models, however, explain the month to month variability as resulting in a critical way from unobservable shocks to money demand and purchasing power parity. It would therefore be of interest in future work to model one or both of these shocks as explicit functions of economic ...

  8. Role of PTEN in the Tumor Microenvironment

    Science.gov (United States)

    2008-06-01

    mouse mammary tumors. Oncogene 24, 6870-6876. 11. Park ES, Lee JS, Woo HG, Zhan F, Shih JH, Shaughnessy JD Jr, Frederic Mushinski J. (2007...between: Pearson : p-value PTEN and ETS2-P (T72) -0.577 < 0.001 PTEN and AKT-P (S473) -0.552 < 0.001 ETS2-P (T72) and AKT-P (S473) 0.947 < 0.001 50μm

  9. Wireless Sensor Networks for High Fidelity Sampling

    Science.gov (United States)

    2007-07-20

    Seismological Laboratory underground seismometer calibration vault. Testing showed that the SiliconDesigns 1221L devices have a noise floor of 32µG...wireless sensor networks. In SIGCOMM 2006, Pisa, Italy , August 2006. [74] Luigi Rizzo. Effective erasure codes for reliable computer communication proto...Proceedings of the seventh annual international conference on Mobile computing and networking, Rome, Italy , July 2001. [86] Alec Woo, Terence Tong, and

  10. Analysis of Subwavelength Metal Hole Array Structure for the Enhancement of Back-Illuminated Quantum Dot Infrared Photodetectors

    Science.gov (United States)

    2013-02-25

    Woo-Yong Jang,2,5,6 Jiangfeng Zhou,3,5 Jun Oh Kim,2 Ajit V. Barve,2 Sinhara Silva,3 Sanjay Krishna,2 S. R. J. Brueck,2 Robert Nelson,1 Augustine Urbas...dots,” C. R. Phys. 4(10), 1133–1154 (2003). 4. G. T. Liu, A. Stintz, H. Li, T. C. Newell, G. L. Gray, P. M. Varangis, K. J. Malloy , and L. F. Lester

  11. The Danish Shoulder Arthroplasty Registry: clinical outcome and short-term survival of 2,137 primary shoulder replacements

    OpenAIRE

    Jeppe V Rasmussen; Jakobsen,John; Brorson, Stig; Olsen, Bo S

    2012-01-01

    The Danish Shoulder Arthroplasty Registry (DSR) was established in 2004. Data are reported electronically by the surgeons. Patient-reported outcome is collected 10–14 months postoperatively using the Western Ontario osteoarthritis of the shoulder index (WOOS). 2,137 primary shoulder arthroplasties (70% women) were reported to the registry between January 2006 and December 2008. Mean age at surgery was 69 years (SD 12). The most common indications were a displaced proximal humeral fracture (54...

  12. Development of Army High-Energy Fuel for Diesel/Turbine-Powered Surface Equipment. Phase II

    Science.gov (United States)

    1981-12-01

    suspect if they differ by more than 55 Rtu per pound and the results by two or more laboratories should be considered suspect if they differ by more...hu3m a a sm ow Woo Is omitns 9 PMmLV in uIM owe ls WWI NMe- Imm W aIN -M I .00 Oft WNW WI MMXCVM IMASY OI. 3111 ~ was a rmus ON A3 116 6 Isa N IL 316

  13. Technology,the Soul of KR Development%技术至上:KR发展的灵魂--韩国船级社高层专访

    Institute of Scientific and Technical Information of China (English)

    王孟霞

    2003-01-01

    @@ 2003年4月30日,韩国船级社(KR)董事会特别会议宣布任命Kap-sook Lee为KR新一任主席兼总裁.Kap-sook Lee接受了本刊记者的专访.同时接受采访的还有KR高级副总裁Tae-Woo Kim以及KR国际事务部总经理Young-Kee Chon.

  14. Airport and Airway System Costs and User Cost Responsibility. Volume 1. Summary Report.

    Science.gov (United States)

    1977-09-01

    8217¢ ,’ :,.,’ " 14" " ." e " e" SIAJ O N. .* . I ".**’- C-’ .I ’ -"I’ V " ’" e- A - SO’ S’ - be ’ "-5’ 0’_,2 _" fl’ b W N C4 * ~ ~ mm m NO M’~ 0 000NEO 0 0 woo

  15. Advanced Technology for Ultra-Low Power System-on-Chip (SoC)

    Science.gov (United States)

    2017-06-01

    GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 61101E 6. AUTHOR(S) Jason Woo, Weicong Li, and Peng Lu 5d. PROJECT NUMBER 1000 5e. TASK NUMBER N/A 5f...Defense Advanced Research Projects AgencyDARPA/MTO 675 North Randolph Street Arlington, VA 22203 AFRL/RYDI 11. SPONSORING/MONITORING AGENCY REPORT...13 Figure 18: (a) Electron Density

  16. Thermal Performance of Low-carbon Prefabricated Timber Housing in the UK

    OpenAIRE

    Adekunle, Timothy Oluseun

    2014-01-01

    The research investigates thermal performance of prefabricated timber housing in the UK due to a growing concern regarding the increase in summertime temperatures, which are expected to occur regularly as global temperatures increase. Furthermore, modern houses are built to meet improved regulations with additional insulation and are more sensitive to potential summertime overheating than older houses. This study examines three UK prefabricated timber housing developments (Bridport, Oxley Woo...

  17. Encryption Devices for Use in a Conditional Access System

    Science.gov (United States)

    2007-11-02

    5341425 Aug., 1994 Wasilewski et al. 5343527 Aug., 1994 Moore. 5381477 Jan., 1995 Beyers, III et al. 5381481 Jan., 1995 Gammie et al. 5400401 Mar., 1995... Wasilewski et al. 5402490 Mar., 1995 Mihm, Jr. 5414773 May., 1995 Handelman. 5420866 May., 1995 Wasilewski . 5425101 Jun., 1995 Woo et al...et al. 5787172 Jul., 1998 Arnold 713/175. 5862220 Jan., 1999 Perlman. 5870474 Feb., 1999 Wasilewski et al. 6005938 Dec., 1999 Banker et al

  18. Antinuclear movement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Hee; Im, Jaeg Yeong

    1988-08-15

    This book is for antinuclear movement. So, this book introduces many articles on nuclear issues of Asia and the pacific area. The titles of articles are the crusades of Reagan by Werner Plaha, contending between super powers in Europe by Alva Reimer Myrdal, claims of resistance by Daniel Ellsberg, nuclear and the Korean Peninsula by Go, Seung Woo, Liberation but of belief of nuclear weapon by Lee, Young Hee and nuclear weapon in Korea by peter Haze.

  19. Momentum and buoyancy transfer in atmospheric turbulent boundary layer over wavy water surface – Part 2: Wind–wave spectra

    Directory of Open Access Journals (Sweden)

    Yu. I. Troitskaya

    2013-10-01

    Full Text Available Drag and mass exchange coefficients are calculated within a self-consistent problem for the wave-induced air perturbations and mean velocity and density fields using a quasi-linear model based on the Reynolds equations with down-gradient turbulence closure. This second part of the report is devoted to specification of the model elements: turbulent transfer coefficients and wave number-frequency spectra. It is shown that the theory agrees with laboratory and field experimental data well when turbulent mass and momentum transfer coefficients do not depend on the wave parameters. Among several model spectra better agreement of the theoretically calculated drag coefficients with TOGA (Tropical Ocean Global Atmosphere COARE (Coupled Ocean–Atmosphere Response Experiment data is achieved for the Hwang spectrum (Hwang, 2005 with the high frequency part completed by the Romeiser spectrum (Romeiser et al., 1997.

  20. Momentum and buoyancy transfer in atmospheric turbulent boundary layer over wavy water surface - Part 2: Wind-wave spectra

    Science.gov (United States)

    Troitskaya, Yu. I.; Ezhova, E. V.; Sergeev, D. A.; Kandaurov, A. A.; Baidakov, G. A.; Vdovin, M. I.; Zilitinkevich, S. S.

    2013-10-01

    Drag and mass exchange coefficients are calculated within a self-consistent problem for the wave-induced air perturbations and mean velocity and density fields using a quasi-linear model based on the Reynolds equations with down-gradient turbulence closure. This second part of the report is devoted to specification of the model elements: turbulent transfer coefficients and wave number-frequency spectra. It is shown that the theory agrees with laboratory and field experimental data well when turbulent mass and momentum transfer coefficients do not depend on the wave parameters. Among several model spectra better agreement of the theoretically calculated drag coefficients with TOGA (Tropical Ocean Global Atmosphere) COARE (Coupled Ocean-Atmosphere Response Experiment) data is achieved for the Hwang spectrum (Hwang, 2005) with the high frequency part completed by the Romeiser spectrum (Romeiser et al., 1997).

  1. Cryptanalysis And Further Improvement Of A Biometric-Based Remote User Authentication Scheme Using Smart Cards

    CERN Document Server

    Das, Ashok Kumar

    2011-01-01

    Recently, Li et al. proposed a secure biometric-based remote user authentication scheme using smart cards to withstand the security flaws of Li-Hwang's efficient biometric-based remote user authentication scheme using smart cards. Li et al.'s scheme is based on biometrics verification, smart card and one-way hash function, and it also uses the random nonce rather than a synchronized clock, and thus it is efficient in computational cost and more secure than Li-Hwang's scheme. Unfortunately, in this paper we show that Li et al.'s scheme still has some security weaknesses in their design. In order to withstand those weaknesses in their scheme, we further propose an improvement of their scheme so that the improved scheme always provides proper authentication and as a result, it establishes a session key between the user and the server at the end of successful user authentication.

  2. Cosmology and stellar equilibrium using Newtonian hydrodynamics with general relativistic pressure

    CERN Document Server

    Baqui, P O; Piattella, O F

    2015-01-01

    We revisit the analysis made by Hwang and Noh [JCAP 1310 (2013)] aiming the construction of a Newtonian set of equations incorporating pressure effects typical of General Relativity theory. We perform in an explicit way the deduction of the Hwang-Noh equations, comparing it with similar computations found in the literature. Later, we investigate stellar equilibrium and cosmology, at background and perturbative levels, using the new set of equations. It is shown that, in this context, the predictions for the background evolution of the universe are deeply changed with respect to the full relativistic theory: the acceleration of the universe is achieved with positive pressure. The properties of neutron stars are reproduced qualitatively, but the upper mass is at least one order of magnitude higher than that obtained in General Relativity. However, the perturbed cosmological equations at small scales reproduce those found in the relativistic context. We argue that this last result may open new possibilities for ...

  3. Triangulating Trimmed NURBS Surfaces

    Science.gov (United States)

    2000-01-01

    Curve and Surface Design: Saint-Malo 1999 381 Pierre-Jean Laurent, Paul Sablonnibre, and Larry L. Schumaker ( eds .), pp. 381-388. Copyright 0 2000 by...the boundary of its neighboring surface. References 1. Baehmann, P. L., S. L. Wittchen , M. S. Shephard, K. R. Grice and M. A. Yerry, Robust...and D. Eppstein, Mesh generation and optimal triangulation, in Computing in Euclidean Geometry, 2nd ed ., D.-Z. Du and F. K. Hwang, ( eds .), World

  4. Tunable PhoXonic Band Gap Materials from Self-Assembly of Block Copolymers and Colloidal Nanocrystals (NBIT Phase II)

    Science.gov (United States)

    2013-12-12

    Principal Investigators: Edwin L. Thomas, MIT and Rice University (and Youngjong Kang – Dept. of Chemistry, Hanyang University) - e-mail address : elt ...from your AOARD supported project: In standard format showing authors, title, journal , issue, pages, and date, for each category list the...following: a) papers published in peer-reviewed journals Kim, E., Kang, C., Baek, H., Hwang, K., Kwak, D., Lee, E., Kang, Y., Thomas, E.L., “Control

  5. Verifying Object-Oriented Programs That Use Subtypes

    Science.gov (United States)

    1989-02-01

    Albert Meyer, Jonathan Rees, Earl Waldin, Jon Riecke, Lalita Jategaonkar, John Lucassen, Mark Reinhold, Brian Oki, Kim Bruce, and Peter Wegner. There...Kathy Yelick, Minoru Kubota, Debbie Hwang, Elliot Kolodner, Suresh Jagannathan, Robert Scheifler, Jon Riecke, Paul Hillner, David Jaeger, Sharon Per...Mark Day, Paul Johnson, Dorothy Curtis, Toby Bloom, Boaz Ben-Zvi, Sanjay Ghemawat, Robert Gruber , Rivka Ladin, Barbara Liskov, John Guttag, Ann

  6. Two-Photon Polymerization of Defects in Photonic Crystals

    Science.gov (United States)

    2006-01-01

    Garcia -Santamaria, H. Miguez, M. Ibisate, F. Meseguer, C. Lopez , Langmuir 2002, 18, 1942. 7. P. Jiang, J. F. Bertone, K. S. Hwang, V. L. Colvin, Chem...Leonard, C. Lopez , F. Meseguer, H. Miguez, J. P. Mondia, G. A. Ozin, O. Toader, H. M. van Driel, Nature 2000, 405, 437. 17. F. Garcia -Santamaria...and Robert Shimmin. It has also been a pleasure working with Christy (Ying-Chieh) Chen, Vinayak Ramanan, Erik Nelson, Wendy Chan, and the rest of

  7. Peptide Transport through the Blood-Brain Barrier

    Science.gov (United States)

    1991-01-01

    nervosa : Relation to state of nutrition , adrenal function, and intensity of depression. J. Clin. Endocrinol. Metab. 64:203-208. 7. Lifson, J.D., Hwang, K.M...activity of the opioid chimeric peptide 7 may be assessed in vivo in rats using the tail-flick analgesia paradigm. The use of cationized rat albumin has...T.P., Chrousos, G.P., and Gold, P.W. (1987): Elevated cerebrospinal fluid levels of immunoreactive corticotropin-releasing hormone in anorexia

  8. Nonlinear Dynamics of Photonics for Optical Signal Processing - Optical Frequency Conversion and Optical DSB-to-SSB Conversion

    Science.gov (United States)

    2015-09-17

    processing - optical frequency conversion and optical DSB -to-SSB conversion 5a. CONTRACT NUMBER FA2386-14-1-0006 5b. GRANT NUMBER Grant 134113...nonlinear dynamics of semiconductor lasers for certain optical signal processing functionalities, including optical DSB -to-SSB conversion, photonic...conversion and optical DSB -to-SSB conversion Performance Period May 30, 2014 ~ May 29, 2015 Principal Investigator Name: Sheng-Kwang Hwang Position

  9. Wavelength-Tunable IR Detector based on Suspended Bilayer Graphene Micro Ribbons

    Science.gov (United States)

    2013-11-05

    transferred onto 300 nm SiO2 substrate confirms good quality monolayer graphene film (For more details see supporting online information.). The...the CVD graphene material or residual doping, we compared the same device before and after etching the sacrificial SiO2 layer. The incident laser...Fuhrer, M. S. Intrinsic and extrinsic performance limits of graphene devices on SiO2 . Nat. Nano 3, 206-209 (2008). 33. Hwang, E. H. & Das Sarma, S

  10. Beyond Authoritarian Personality: The Culture-Inclusive Theory of Chinese Authoritarian Orientation

    Science.gov (United States)

    Chien, Chin-Lung

    2016-01-01

    In a dyad interaction, respecting and obeying those with high status (authority) is highly valued in Chinese societies. Regarding explicit behaviors, Chinese people usually show respect to and obey authority, which we call authoritarian orientation. Previous literature has indicated that Chinese people have a high degree of authoritarian personality, which was considered a national character. However, under Confucian relationalism (Hwang, 2012a), authoritarian orientation is basically an ethical issue, and thus, should not be reduced to the contention of authoritarian personality. Based on Yang's (1993) indigenous conceptualization, Chien (2013) took an emic bottom-up approach to construct an indigenous model of Chinese authoritarian orientation; it represents a “culture-inclusive theory.” However, Chien's model lacks the role of agency or intentionality. To resolve this issue and to achieve the epistemological goal of indigenous psychology (that is, “one mind, many mentalities”), this paper took the “cultural system approach” (Hwang, 2015b) to construct a culture-inclusive theory of authoritarian orientation in order to represent the universal mind of human beings as well as the mentalities of people in a particular culture. Two theories that reflect the universal mind, the “Face and Favor model” (Hwang, 1987) and the “Mandala Model of Self” (Hwang, 2011a,c), were used as analytical frameworks for interpreting Chien's original model. The process of constructing the culture-inclusive theory of authoritarian orientation may represent a paradigm for the construction of indigenous culture-inclusive theories while inspiring further development. Some future research directions are proposed herein. PMID:27445894

  11. Modelos de masculinidad en la literatura chino-americana contemporánea

    OpenAIRE

    Soria Somoza, Carolina

    2016-01-01

    [Resumen] Modelos de masculinidad en la literatura chino-americana contemporánea Esta tesis doctoral estudia los modelos de masculinidad presentes en la literatura chino-americana contemporánea. Para ello, analizo las obras de autores tan representativos como Frank Chin, Louis Chu, David Henry Hwang, Gish Jen, Ha Jin y Maxine Hong Kingston. Mi principal objetivo es examinar las diferencias entre aquellos modelos que resulten obsoletos y estereotípicos de aquellos que puedan ...

  12. AN IMPROVED DOS-RESISTANT ID-BASED PASSWORD AUTHENTICATION SCHEME WITHOUT USING SMART CARD

    Institute of Scientific and Technical Information of China (English)

    Wen Fengtong; Li Xuelei; Cui Shenjun

    2011-01-01

    In 2010,Hwang,et al.proposed a 'DoS-resistant ID-based password authentication scheme using smart cards' as an improvement of Kim-Lee-Yoo's ‘ID-based password authentication scheme'.In this paper,we cryptanalyze Hwang,et al.'s scheme and point out that the revealed session key could threat the security of the scheme.We demonstrate that extracting information from smart cards is equal to knowing the session key.Thus known session key attacks are also effective under the assumption that the adversary could obtain the information stored in the smart cards.We proposed an improved scheme with security analysis to remedy the weaknesses of Hwang,et al.'s scheme.The new scheme does not only keep all the merits of the original,but also provides several additional phases to improve the flexibility.Finally,the improved scheme is more secure,efficient,practical,and convenient,because elliptic curve cryptosystem is introduced,the expensive smart cards and synchronized clock system are replaced by mobile devices and nonces.

  13. Trojan Horse Attack Free Fault-Tolerant Quantum Key Distribution Protocols Using GHZ States

    Science.gov (United States)

    Chang, Chih-Hung; Yang, Chun-Wei; Hwang, Tzonelih

    2016-09-01

    Recently, Yang and Hwang (Quantum Inf. Process. 13(3): 781-794, 19) proposed two fault-tolerant QKD protocols based on their proposed coding functions for resisting the collective noise, and their QKD protocols are free from Trojan horse attack without employing any specific detecting devices (e.g., photon number splitter (PNS) and wavelength filter). By using four-particle Greenberger-Horne-Zeilinger (GHZ) state and four-particle GHZ-like state in their proposed coding functions, Yang and Hwang's QKD protocols can resist each kind of the collective noise-collective-dephasing noise, collective-rotation noise. However, their proposed coding function can be improved by the utilization of three-particle GHZ state (three-particle GHZ-like state) instead of four-particle GHZ state (four-particle GHZ-like state) that will eventually reduce the consumption of the qubits. As a result, this study proposed the improved version of Yang and Hwang's coding functions to enhance the qubit efficiency of their schemes from 20 % to 22 %.

  14. Hexavalent chromium reduction by aerobic heterotrophic bacteria indigenous to chromite mine overburden

    Directory of Open Access Journals (Sweden)

    Dey Satarupa

    2013-01-01

    Full Text Available Microbiological analysis of overburden samples collected from chromite mining areas of Orissa, India revealed that they are rich in microbial density as well as diversity and dominated by Gramnegative (58% bacteria. The phenotypically distinguishable bacterial isolates (130 showed wide degree of tolerance to chromium (2-8 mM when tested in peptone yeast extract glucose agar medium. Isolates (92 tolerating 2 mM chromium exhibited different degrees of Cr+6 reducing activity in chemically defined Vogel Bonner (VB broth and complex KSC medium. Three potent isolates, two belonging to Arthrobacter spp. and one to Pseudomonas sp. were able to reduce more than 50 and 80% of 2 mM chromium in defined and complex media respectively. Along with Cr+6 (MIC 8.6-17.8 mM, the isolates showed tolerance to Ni+2, Fe+3, Cu+2 and Co+2 but were extremely sensitive to Hg+2 followed by Cd+2, Mn+2 and Zn+2. In addition, they were resistant to antibiotics like penicillin, methicillin, ampicillin, neomycin and polymyxin B. During growth under shake-flask conditions, Arthrobacter SUK 1201 and SUK 1205 showed 100% reduction of 2 mM Cr+6 in KSC medium with simultaneous formation of insoluble precipitates of chromium salts. Both the isolates were also equally capable of completely reducing the Cr+6 present in mine seepage when grown in mine seepage supplemented with VB concentrate.

  15. Effects of landuse change on the hydrologic regime of the Mae Chaem river basin, NW Thailand

    Science.gov (United States)

    Thanapakpawin, P.; Richey, J.; Thomas, D.; Rodda, S.; Campbell, B.; Logsdon, M.

    2007-02-01

    SummaryConflicts between upland shifting cultivation, upland commercial crops, and lowland irrigated agriculture cause water resource tension in the Mae Chaem watershed in Chiang Mai, Thailand. In this paper, we assess hydrologic regimes of the Mae Chaem River with landuse change. Three plausible future forest-to-crop expansion scenarios and a scenario of crop-to-forest reversal were developed based on the landcover transition from 1989 to 2000, with emphasis on influences of elevation bands and irrigation diversion. Basin hydrologic responses were simulated using the Distributed Hydrology Soil Vegetation Model (DHSVM). Meteorological data from six weather stations inside and adjacent to the Mae Chaem watershed during the period 1993-2000 were the climate inputs. Computed stream flow was compared to observed discharge at Ban Mae Mu gauge on Mae Mu river, Ban Mae Suk gauge on Mae Suk river, and at Kaeng Ob Luang, located downstream from the district town in Mae Chaem. With current assumptions, expansion of highland crop fields led to slightly higher regulated annual and wet-season water yields compared to similar expansion in the lowland-midland zone. Actual downstream water availability was sensitive to irrigation diversion. This modeling approach can be a useful tool for water allocation for small watersheds undergoing rapid commercialization, because it alerts land managers to the potential range of water supply in wet and dry seasons, and provides information on spatial distribution of basin hydrologic components.

  16. Rigid Holography and Six-Dimensional N=(2,0) Theories on AdS_5 times S^1

    CERN Document Server

    Aharony, Ofer; Rey, Soo-Jong

    2015-01-01

    Field theories on anti-de Sitter (AdS) space can be studied by realizing them as low-energy limits of AdS vacua of string/M theory. In an appropriate limit, the field theories decouple from the rest of string/M theory. Since these vacua are dual to conformal field theories (CFTs), this relates some of the observables of these field theories on AdS to a subsector of the dual CFTs. We exemplify this `rigid holography' by studying in detail the 6d N=(2,0) A_{K-1} superconformal field theory (SCFT) on AdS_5xS^1, with equal radii for AdS_5 and for S^1. We choose specific boundary conditions preserving sixteen supercharges that arise when this theory is embedded into Type IIB string theory on AdS_5xS^5/Z_K. On R^{4,1}xS^1, this 6d theory has a 5(K-1)-dimensional moduli space, with unbroken 5d SU(K) gauge symmetry at (and only at) the origin. On AdS_5xS^1, the theory has a 2(K-1)-dimensional `moduli space' of supersymmetric configurations. We argue that in this case the SU(K) gauge symmetry is unbroken everywhere in...

  17. Post-death cloning of endangered Jeju black cattle (Korean native cattle): fertility and serum chemistry in a cloned bull and cow and their offspring.

    Science.gov (United States)

    Kim, Eun Young; Song, Dong Hwan; Park, Min Jee; Park, Hyo Young; Lee, Seung Eun; Choi, Hyun Yong; Moon, Jeremiah Jiman; Kim, Young Hoon; Mun, Seong Ho; Oh, Chang Eon; Ko, Moon Suck; Lee, Dong Sun; Riu, Key Zung; Park, Se Pill

    2013-12-17

    To preserve Jeju black cattle (JBC; endangered native Korean cattle), a pair of cattle, namely a post-death cloned JBC bull and cow, were produced by somatic cell nuclear transfer (SCNT) in a previous study. In the present study, we examined the in vitro fertilization and reproductive potentials of these post-death cloned animals. Sperm motility, in vitro fertilization and developmental capacity were examined in a post-death cloned bull (Heuk Oll Dolee) and an extinct nuclear donor bull (BK94-13). We assessed reproductive ability in another post-death cloned cow (Heuk Woo Sunee) using cloned sperm for artificial insemination (AI). There were no differences in sperm motility or developmental potential of in vitro fertilized embryos between the post-death cloned bull and its extinct nuclear donor bull; however, the embryo development ratio was slightly higher in the cloned sperm group than in the nuclear donor sperm group. After one attempt at AI, the post-death cloned JBC cow became pregnant, and gestation proceeded normally until day 287. From this post-death cloned sire and dam, a JBC male calf (Heuk Woo Dolee) was delivered naturally (weight, 25 kg). The genetic paternity/maternity of the cloned JBC bull and cow with regard to their offspring was confirmed using International Society for Animal Genetics standard microsatellite markers. Presently, Heuk Woo Dolee is 5 months of age and growing normally. In addition, there were no significant differences in blood chemistry among the post-death cloned JBC bull, the cow, their offspring and cattle bred by AI. This is the first report showing that a pair of cattle, namely, a post-death cloned JBC bull and cow, had normal fertility. Therefore, SCNT can be used effectively to increase the population of endangered JBC.

  18. Fat Hoffman graphs with smallest eigenvalue at least $-1-\\tau$

    CERN Document Server

    Munemasa, Akihiro; Taniguchi, Tetsuji

    2011-01-01

    In this paper, we show that all fat Hoffman graphs with smallest eigenvalue at least -1-\\tau, where \\tau is the golden ratio, can be described by a finite set of fat (-1-\\tau)-irreducible Hoffman graphs. In the terminology of Woo and Neumaier, we mean that every fat Hoffman graph with smallest eigenvalue at least -1-\\tau is an H-line graph, where H is the set of isomorphism classes of maximal fat (-1-\\tau)-irreducible Hoffman graphs. It turns out that there are 37 fat (-1-\\tau)-irreducible Hoffman graphs, up to isomorphism.

  19. Strike Operations: Contingency Operations with Light-Heavy-Special Operations Forces.

    Science.gov (United States)

    1991-06-07

    ocnditions, esployin night vision devices, vehicle thermal sights, and surveillance eqquipent. * Provides ogzanic indirec fire supot (107Mu [4.2"] Srtar...operations under limited visibility, employing night vision devices and vehicle thermal sights. * Conducts assault breadhes. * Onducts patrols (mounted...PIN ISO". Pr SIM lisle OWM woo I n11Ř ofl I O1 ** VIM-*M I PP It" PAWAO FIGMR 3-2-34. SrJPPO PLAMWt (LB;FM , Condut offensive and defensive cperations

  20. Reference: 785 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available eun et al. 2008 Jul. Plant Cell 20(7):1899-914. Ubiquitination is involved in diverse cellular processes in ...ning E3 ubiquitin (Ub) ligases. The PUB22 and PUB23 genes were rapidly and coordinately induce...n greater drought tolerance. These results indicate that PUB22 and PUB23 function as negative regulators in ...oles in response to drought stress. 7 1899-914 18664614 2008 Jul The Plant cell Cho Seok Keun|Kim Woo Taek|Kwak June M|Ryu Moon Young|Song Charlotte

  1. Real-time exposure fusion on a mobile computer

    CSIR Research Space (South Africa)

    Bachoo, AK

    2009-12-01

    Full Text Available Romeny, J. Zimmer- man, and K. Zuiderveld, “Adaptive histogram equalization and its variations,” Computer Vision, Graphics and Image Processing, vol. 39, pp. 355–368, 1987. [8] R. Gonzalez and R. Woods, Digital image processing. Addison-Wesley... Publishing Company, 2002. [9] R. Rost, OpenGL(R) Shading Language (2nd Edition). Addison-Wesley Professional, 2006. [10] D. Shreiner, M. Woo, J. Neider, and T. Davis, OpenGL Programming Guide. Addison-Wesley Professional, 2007. [11] A. Reza...

  2. Key Oil Projects Look to Private Capital

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    China's state-dominated oil sector has started to make efforts to woo private capital amid a growth slowdown in the world's second-largest economy. China National Petroleum Corporation (CNPC), a state-owned oil giant, has recently signed an investment framework agreement with investors, including the National Council for Social Security Fund (NCSSF), Urban Infrastructure Construction Investment Fund (UICIF) and Baosteel Group Corporation, to jointly develop China's third west- east natural gas transmission project.

  3. Seks ja töö / Andres Maimik

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    2000-01-01

    Filmifestivalil "Armastus ja Anarhia" ("Rakkautta & Anarkiaa") 21.09.- 01.10. nähtud filmidest : Rosa von Praudheimi eluloofilm "Einstein of Sex", Julien Temple dokumentaalfilm "The Filth and the Fury", Virginie Despentes ja Coralie Trinh Thi "Baise moi!" ("Vägista mind!"), Catherine Breillat "Une vraie Jeune Fille" ("Päris noor tüdruk"), Francois Ozoni Rainer Werner Fassbinderi näidendi järgi tehtud film "Gouttes d'eau sur pierres brulantes" ("Veetilgad põlevatel kividel"), Jang Sun Woo "Gojimal" ("Valed") ja Laurent Cantet' "Ressources humaines" ("Inimressursid")

  4. Central black hole masses of galaxies

    Institute of Scientific and Technical Information of China (English)

    樊军辉

    2003-01-01

    In this paper, the stellar velocity dispersions in the host galaxies are used to estimate the central black hole masses for a sample of elliptical galaxies. We find that the central black hole masses are in the range of 10(5.5-9.5) M(○). Based on the estimated masses in this paper and those by Woo & Urry (2002) and the measured host galaxy absolute magnitude,a relation, log(MBH/M(○)) = -(0.25 ± 4.3 × 10-3)MR + (2.98 4 0.208) is found for central black hole mass and the host galaxy magnitude. Some discussions are presented.

  5. Test of total heat flux from wood crib fire in and outside compartment

    Directory of Open Access Journals (Sweden)

    Qiang Xu

    2007-01-01

    Full Text Available Woo d crib fires were studied by using of ISO 9705 Room. These free burning tests with different heat release rate were conducted inside room and outside room (under the hood. Thermal condition around crib fire was measured by using of thermocouples, total heat flux gauge, gas concentration analyzer, and standard instrumentations for heat release rate measurement in ISO 9705 Room. This paper focuses on the total heat flux to the surrounding area from wood crib fire. The correlation between heat release rate and total heat flux is presented. Wall and space effect is also analyzed.

  6. X-Ray Absorption Spectroscopy of Uranium Dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Tobin, J G

    2010-12-10

    After the CMMD Seminar by Sung Woo Yu on the subject of the x-ray spectroscopy of UO2, there arose some questions concerning the XAS of UO2. These questions can be distilled down to these three issues: (1) The validity of the data; (2) The monchromator energy calibration; and (3) The validity of XAS component of the figure shown. The following will be shown: (1) The data is valid; (2) It is possible to calibrate the monchromator; and (3) The XAS component of the above picture is correct. The remainder of this document is in three sections, corresponding to these three issues.

  7. Study on Function of Vegetation s Preventing Soil Erosion in Small Watershed of the Loess Area

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    This paper analyzes the function of preventing soil erosion of the different woodlands according to a long-term fixed-position observation, and points out that the steep slope plantation of uncontrolled measures for soil and water conservation is apt to produce sediment Forestland has very strong effect in soil and water conservation when the biomass of arbor in the hillslope is over 1 4.51t/ha. Through analyzing the function of soil and water conservation about forestland (arbor, bush and the mixed woo...

  8. Seks ja töö / Andres Maimik

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    2000-01-01

    Filmifestivalil "Armastus ja Anarhia" ("Rakkautta & Anarkiaa") 21.09.- 01.10. nähtud filmidest : Rosa von Praudheimi eluloofilm "Einstein of Sex", Julien Temple dokumentaalfilm "The Filth and the Fury", Virginie Despentes ja Coralie Trinh Thi "Baise moi!" ("Vägista mind!"), Catherine Breillat "Une vraie Jeune Fille" ("Päris noor tüdruk"), Francois Ozoni Rainer Werner Fassbinderi näidendi järgi tehtud film "Gouttes d'eau sur pierres brulantes" ("Veetilgad põlevatel kividel"), Jang Sun Woo "Gojimal" ("Valed") ja Laurent Cantet' "Ressources humaines" ("Inimressursid")

  9. Using Gagne’s instructional model in phlebotomy education

    Directory of Open Access Journals (Sweden)

    Woo WH

    2016-08-01

    Full Text Available Wee Hong Woo School of Chemical & Life Sciences, Singapore Polytechnic, Singapore Abstract: As the role of a phlebotomist in a clinical setting involves patient interactions, ­correct patient identification, and blood specimen accessioning, it is essential that the phlebotomy education pay attention to these procedural tasks to inculcate a culture of patient safety. Using the Gagne’s nine events of instruction as the basis of teaching model, this paper describes the lesson plan for teaching the topic of patient approach to a group of phlebotomy students without prior clinical experience. Keywords: venipuncture, Gagne’s model, instructional design, patient handling, Peyton’s steps

  10. Spatial Disorientation Analysis of AF Safety Center Mishap Data

    Science.gov (United States)

    2006-02-01

    ISO ISO 140 120 100 80 60- 40 Figure 15. Data set A airspeed (knots) 5000. 4000 3000 2000 1000 0 -1000 -2000 -3000 -4000-woo...descend from 20,000’ MSL (Figure 19). t-At,- - - Ra,,t 26000 24000 220OO 20000 18000 16000 14000 12000 4000 2000 0 Figure 19. Data set B altitude and...430 yA 420 410 400 390 380 370V 380 350 340 330 320 310 Figure 35. Data set D calibrated airspeed (knots) VSI 26000 24000 22000 20000 18000

  11. Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation

    OpenAIRE

    Yoon TH; Kim MJ; Suh YJ; Lim EJ; Kim RK; Woo SJ; Hyun KH; Kwon DW; Yoon CH; Yoo KC; Lee SJ

    2012-01-01

    Ki-Chun Yoo1, Chang-Hwan Yoon1, Dongwook Kwon2, Kyung-Hwan Hyun1, Soo Jung Woo1, Rae-Kwon Kim1, Eun-Jung Lim1, Yongjoon Suh1, Min-Jung Kim1, Tae Hyun Yoon2, Su-Jae Lee11Laboratory of Molecular Biochemistry, 2Laboratory of Nanoscale Characterization and Environmental Chemistry, Department of Chemistry, Hanyang University, Seoul, Republic of KoreaBackground: Titanium dioxide (TiO2) has been widely used in many areas, including biomedicine, cosmetics, and environmental engineering. Recently, it ...

  12. All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 14. (Aberdeen, North Carolina-Zanesville, Ohio)

    Science.gov (United States)

    1988-01-01

    030-4 1 0 -. 4 co (D co tn L) -4 ()(D 0 a 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -1 14 -4 -1 -1 -4 " -0 -4 -4 -1 -4 -4 -4 -4 CLIMO -4 loomv"< ɘ ɘ...0000000000000000000000000000 "tMO-4 10000000 1-4-4 -O � x 1 MO-4 1 -JWWWWWW Z<< WW CLIMO -4 lwmmmmmm woo "M <IMO-4 IMMMMMMM 0<< CIM W I M

  13. Glyburide - Novel Prophylaxis and Effective Treatment for Blast-Traumatic Brain Injury

    Science.gov (United States)

    2013-10-01

    the solution as needed using a minimum amount of NaOH to a pH approximately 8 to 8.5. Solutions prepared in this way and stored at 37°C for 48 hours... Sensor Walk, an Pre-train on 24 hr Results Fig. 5 sions. only Blast ficits in no eous Reari truncal sta nt with glib lans test o laxis trea...Simard JM, Woo SK, Bhatta S, Gerzanich V. Drugs acting on SUR1 to treat CNS ischemia and trauma. Curr Opin Pharmacol 2008; 8(1):42-9. PM:18032110

  14. Discriminating neural representations of physical and social pains: how multivariate statistics challenge the "shared representation" theory of pain.

    Science.gov (United States)

    Rogachov, A; Cheng, J C; DeSouza, D D

    2015-11-01

    Overlapping functional magnetic resonance imaging (fMRI) activity elicited by physical pain and social rejection has posited a common neural representation between the two experiences. However, Woo and colleagues (Nat Commun 5: 5380, 2014) recently used multivariate statistics to challenge the "shared representation" theory of pain. This study has implications in the way results from fMRI studies are interpreted and has the potential of broadening our understanding of different pain states and future development of personalized medicine. Copyright © 2015 the American Physiological Society.

  15. Fabrication Procedure for Rugged and Breathable Forms of Stretchable Electronics with Adherent and Composite Substrates

    OpenAIRE

    2014-01-01

    Authors: Kyung-In Jang, Sang Youn Han, Sheng Xu, Kyle E. Mathewson, Yihui Zhang, Jae-Woong Jeong, Gwang-Tae Kim, R. Chad Webb, Jung Woo Lee, Thomas J. Dawidczyk, Rak Hwan Kim, Young Min Song, Woon-Hong Yeo, Stanley Kim, Huanyu Cheng, Sang Il Rhee, Jeahoon Chung, Byunggik Kim, Ha Uk Chung, Dongjun Lee, Yiyuan Yang, Moongee Cho, John G. Gaspar, Ronald Carbonari, Monica Fabiani et al. ### Abstract We introduce materials and composite designs for thin, breathable, soft electronics that ca...

  16. Mobilisasi Islamis Damai di Dunia Muslim: Peran Partisipasi Politik dan Kapasitas Negara

    Directory of Open Access Journals (Sweden)

    Testriono Testriono

    2010-08-01

    Full Text Available Book Review : Julie Chernov Hwang, Peaceful Islamist Mobilization in the Muslim World: What Went Right (New York: Palgrave Macmillan, 2009, xviii + 212This book seeks to explain the variations within the Islamist mobilizations, which can be classified into: first, peaceful mobilization, which includes the creation of political parties, election, cooperation, creating civic alliance, and building civil movements. Second category is violent Islamist mobilizations articulated in the form of rebellion, riot, collective violence, and attacks on individuals and groups, minority groups, and private property.Copyright (c 2014 by SDI. All right reserved.DOI: 10.15408/sdi.v17i2.465

  17. Static shape control of a flat shell structure

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The eight-node and forty-DOF piezoelectric shell element were applied to shape control of a flat shell structure. By the direct and converse effects, a distributed piezoelectric sensor layer was used to monitor the shape deformation and a distributed actuator layer was used to suppresse the deflection. A finite element model was for static response of laminated shell with piezoelectric sensors/actuators was derived. The model was verified by calculating piezoelectric polymeric PVDF bimorph beam. The results are in good agreement with those obtained by theoretical analysis of Tzou[1] and Hwang[2]. A case study of the static shape control of a flat shell structure is presented.

  18. La displacement driven Double-exchange like mediation in Titanium $d_{xy}$ ferromagnetism at the LaAlO$_3$/SrTiO$_3$

    OpenAIRE

    Odkhuu, Dorj; Rhim, S H; Shin, Dongbin; Park, Noejung

    2015-01-01

    The epitaxial atomistic interfaces of two insulating oxides, LaAlO$_3$ (LAO)/SrTiO$_3$ (STO), have attracted great interest owing to rich emergent phenomena \\cite{hwang12:nmat,coey13:mrs,ohtomo04:} such as interface metallicity \\cite{ohtomo04:,nakagawa06:}, thickness dependent insulator-metal transition \\cite{huijben06:nmat}, superconductivity \\cite{N.Reyren08312007}, ferromagnetism \\cite{brinkman.07:natmat}, and even their coexistence \\cite{bert11:nphys,li11:nphys,dikin11:prl}. However, the ...

  19. Widefield Two-Photon Excitation without Scanning: Live Cell Microscopy with High Time Resolution and Low Photo-Bleaching.

    Directory of Open Access Journals (Sweden)

    Rumelo Amor

    Full Text Available We demonstrate fluorescence imaging by two-photon excitation without scanning in biological specimens as previously described by Hwang and co-workers, but with an increased field size and with framing rates of up to 100 Hz. During recordings of synaptically-driven Ca(2+ events in primary rat hippocampal neurone cultures loaded with the fluorescent Ca(2+ indicator Fluo-4 AM, we have observed greatly reduced photo-bleaching in comparison with single-photon excitation. This method, which requires no costly additions to the microscope, promises to be useful for work where high time-resolution is required.

  20. Widefield two-photon excitation without scanning: live cell microscopy with high time resolution and low photo-bleaching

    CERN Document Server

    Amor, Rumelo; Robb, Gillian; Wilson, Louise; Rahman, Nor Zaihana Abdul; Dempster, John; Amos, William Bradshaw; Bushell, Trevor J; McConnell, Gail

    2015-01-01

    We demonstrate fluorescence imaging by two-photon excitation without scanning in biological specimens as previously described by Hwang and co-workers, but with an increased field size and with framing rates of up to 100 Hz. During recordings of synaptically-driven Ca$^{2+}$ events in primary rat neurone cultures loaded with the fluorescent Ca$^{2+}$ indicator Fluo-4 AM, we have observed greatly reduced photo-bleaching in comparison with single-photon excitation. This method, which requires no costly additions to the microscope, promises to be useful for work where high time-resolution is required.

  1. Focused Ion Beam Fabrication of Graded Channel Field Effect Transistors (FETs) in GaAs and Si

    Science.gov (United States)

    1988-11-21

    Appl. Phys. 22, L444 (1983). (1981). "A. Wagner and T. M. Hall, J. Vac. Sci. Technol. 16, 1871 (1979). 𔃼T. Shiokawa , P. H. Kim, K. Toyoda. and S...Hwang, R. Bliat, M. Koza, H. W. ’T. Shiokawa , P. H. Kim, K. Toyoda, S. Nama, K. Gamo, R. Aihara. and Yoon, and P. Mei, AppI. Phys. Lett. 49, 701 (1986...Vac. Sci. Technol. B 3,67 (1985). ’K. Nakamura, T. Nozaki. T. Shiokawa . K. Toyoda. and S. Namba, Jpn. ŚY. Ochiai, K. Shihoyama. T. Shiokawa , K

  2. Investigation of a radio frequency-driven multicusp ion source of the diagnostic neutral beam for the Hanbit device at Korea Basic Science Institute

    Science.gov (United States)

    Yang, H. L.; Yoo, S. J.; Hwang, S. M.; Chung, K. H.

    2000-02-01

    A radio frequency-driven multicusp ion source has been fabricated and tested as a part of the development of a diagnostic neutral beam for the Hanbit magnetic mirror device [S. M. Hwang et al., Trans. Fusion Technol. 35, 99 (1999)]. Hydrogen plasma produced by a three-and-one-half turn antenna and rf power system with 2.5 kW, continuous wave (cw) 1.874 MHz was extracted through a single-aperture accel-decel system. The first results of the ion beam extraction experiments are described in this article.

  3. Physico-chemical and antioxidant properties of four mango (Mangifera indica L.) cultivars in China.

    Science.gov (United States)

    Liu, Feng-Xia; Fu, Shu-Fang; Bi, Xiu-Fang; Chen, Fang; Liao, Xiao-Jun; Hu, Xiao-Song; Wu, Ji-Hong

    2013-05-01

    Four principal mango cultivars (Tainong No.1, Irwin, JinHwang and Keitt) grown in southern China were selected, and their physico-chemical and antioxidant properties were characterized and compared. Of all the four cultivars, Tainong No.1 had highest content of total phenols, ρ-coumaric acid, sinapic acid, quercetin, titratable acidity, citric acid, malic acid, fructose, higher antioxidant activities (DPPH, FRAP) and L(*), lower pH, PPO activity and individual weight. Keitt mangoes showed significantly (pmangoes exhibited significantly (pmango cultivars to be differentiated clearly based on all these physico-chemical and antioxidant properties determined in the study. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Trapped Atoms in One-Dimensional Photonic Crystals

    Science.gov (United States)

    2013-08-09

    2002 J. Opt. Soc. Am. B 19 2052 [39] Koenderink A F, Kafesaki M, Soukoulis C M and Sandoghdar V 2006 J. Opt. Soc. Am. B 23 1196 [40] Manga Rao V S C...032509 [55] Hwang J K, Ryu H Y and Lee Y H 1999 Phys. Rev. B 60 4688–95 [56] Yao P, Manga Rao V S C and Hughes S 2010 Laser Photon. Rev. 4 499–516 New Journal of Physics 15 (2013) 083026 (http://www.njp.org/)

  5. Key Residues of Outer Membrane Protein OprI Involved in Hexamer Formation and Bacterial Susceptibility to Cationic Antimicrobial Peptides

    OpenAIRE

    Chang, Ting-Wei; Wang, Chiu-Feng; Huang, Hsin-Jye; Wang, Iren; Hsu, Shang-Te Danny; Liao, You-Di

    2015-01-01

    Antimicrobial peptides (AMPs) are important components of the host innate defense mechanism against invading pathogens. Our previous studies have shown that the outer membrane protein, OprI from Pseudomonas aeruginosa or its homologue, plays a vital role in the susceptibility of Gram-negative bacteria to cationic α-helical AMPs (Y. M. Lin, S. J. Wu, T. W. Chang, C. F. Wang, C. S. Suen, M. J. Hwang, M. D. Chang, Y. T. Chen, Y. D. Liao, J Biol Chem 285:8985–8994, 2010, http://dx.doi.org/10.1074...

  6. Planar Dipole Input Resistance vs. Trace Thickness for Different Materials

    Science.gov (United States)

    2014-09-01

    antenna for RFID applications. IEEE Xplore Digital Library (2014): n. pag. Web. 31 July 2014. 2. Rida A, Yang L, Vyas R, Tentzeris MM. Conductive inkjet...printed antennas on flexible low-cost paper-based substrates for RFID and WSN applications. IEEE Xplore Digital Library (2014): n. pag. Web. 31 July...2014. 3. Kim J-Y, Hwang C-R, Jo S-H, Jung W-G. Highly clear conductive polymer electrode Films hybridized with gold nanoparticles. IEEE Xplore Digital

  7. Advance in next Century nanoCMOSFET research

    Science.gov (United States)

    Hwang, Huey-Liang; Chiou, Yan-Kai; Chang, Che-Hao; Wang, Chen-Chan; Lee, Kun-Yu; Wu, Tai-Bor; Kwo, Raynien; Hong, Minghwei; Chang-Liao, Kuei-Shu; Lu, Chun-Yuan; Lu, Chun-Chang; Chiu, Fu-Chien; Chen, Chun-Heng; Lee, Joseph Ya-Min; Chin, Albert

    2007-10-01

    It is well known that Taiwan's IC industry is in the very leading front of the world, and production of 65 nm devices was launched in 2006. Within a few years, the need of high-k dielectrics and metal gates is eminent and truly indispensable. Professor H.L. Hwang (the author) organized 12 professors and 50 graduate students of National Tsing Hua University and Chiao Tung University, and executed this particular project, which is sponsored by the Ministry of Economic Affairs of Republic of China, and is aimed at treating efficiently this problem and transferred the critical technologies to industry in a time frame of 3 years.

  8. Origin of Charge Density at LaAlO3 on SrTiO3 Heterointerfaces: Possibility of Intrinsic Doping

    Science.gov (United States)

    Siemons, Wolter; Koster, Gertjan; Yamamoto, Hideki; Harrison, Walter A.; Lucovsky, Gerald; Geballe, Theodore H.; Blank, Dave H. A.; Beasley, Malcolm R.

    2007-05-01

    As discovered by Ohtomo and Hwang, a large sheet charge density with high mobility exists at the interface between SrTiO3 and LaAlO3. Based on transport, spectroscopic, and oxygen-annealing experiments, we conclude that extrinsic defects in the form of oxygen vacancies introduced by the pulsed laser deposition process used by all researchers to date to make these samples is the source of the large carrier densities. Annealing experiments show a limiting carrier density. We also present a model that explains the high mobility based on carrier redistribution due to an increased dielectric constant.

  9. 'We aren't quite as good, but we sure are cheap': prospects for disruptive innovation in medical care and insurance markets.

    Science.gov (United States)

    Pauly, Mark V

    2008-01-01

    The concept of "disruptive innovation" by new products of moderately lower quality and much lower cost is useful for the medical care sector. Such products are rarely offered, and when they are (as in the case of health maintenance organizations), they are subject to intense criticism. This Perspective argues that both the legal system and accepted discourse in public policy have inhibited discussion of such alternatives; indeed, the paper by Jason Hwang and Clay Christensen loses its focus on them at the end. The applicability of this concept is quite limited but, given sufficient changes in framing and regulating, might be helpful in the future.

  10. Metabolomic analysis of methyl jasmonate-Induced triterpenoid production in the medicinal herb Centella asiatica (L.) Urban

    CSIR Research Space (South Africa)

    James, TJ

    2013-04-01

    Full Text Available . Palazón, J.; Bonfill, R.M.C.M.; Mallol, A.; Moyano, E.; Morales, C.; Pinol, M.T. Elicitation of different Panax ginseng transformed root phenotypes for an improved ginsenoside production. Plant Physiol. Biochem. 2003, 41, 1019–1025. 22. Fritz, V... 19. Kim, O.T.; Kim, S.H.; Ohyama, K.; Muranaka, T.; Choi, Y.E.; Lee, H.Y.; Kim, M.Y.; Hwang, B. Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase. Plant Cell...

  11. Cryptanalysis of an Efficient Signcryption Scheme with Forward Secrecy Based on Elliptic Curve

    CERN Document Server

    Toorani, Mohsen; 10.1109/ICCEE.2008.147

    2010-01-01

    The signcryption is a relatively new cryptographic technique that is supposed to fulfill the functionalities of encryption and digital signature in a single logical step. Several signcryption schemes are proposed throughout the years, each of them having its own problems and limitations. In this paper, the security of a recent signcryption scheme, i.e. Hwang et al.'s scheme is analyzed, and it is proved that it involves several security flaws and shortcomings. Several devastating attacks are also introduced to the mentioned scheme whereby it fails all the desired and essential security attributes of a signcryption scheme.

  12. Pattern recognition in speech and language processing

    CERN Document Server

    Chou, Wu

    2003-01-01

    Minimum Classification Error (MSE) Approach in Pattern Recognition, Wu ChouMinimum Bayes-Risk Methods in Automatic Speech Recognition, Vaibhava Goel and William ByrneA Decision Theoretic Formulation for Adaptive and Robust Automatic Speech Recognition, Qiang HuoSpeech Pattern Recognition Using Neural Networks, Shigeru KatagiriLarge Vocabulary Speech Recognition Based on Statistical Methods, Jean-Luc GauvainToward Spontaneous Speech Recognition and Understanding, Sadaoki FuruiSpeaker Authentication, Qi Li and Biing-Hwang JuangHMMs for Language Processing Problems, Ri

  13. Trends in savanna structure and composition along an aridity gradient in the Kalahari

    CSIR Research Space (South Africa)

    Scholes, RJ

    2002-06-01

    Full Text Available . Elsewhere, they occupy clayey, alkaline soils derived either from Triassic shales and mudstones, in the valleys of the Zambezi, Limpopo and Cunene rivers and their major tributaries, or from Jurassic basalts. Table 3. Woody plant basal area, canopy cover.... FAO, Rome, IT. Childes, S.I. & Walker, B.H. 1987. Ecology and dynamics of the woody vegetation on the Kalahari sands in Hwange National Park, Zimbabwe. Vegetatio 72: 111-128. Cole, M.M. & Brown, R.C. 1976. The vegetation of the Ghanzi area of western...

  14. Chronic depression treated successfully with novel taping therapy: a new approach to the treatment of depression

    OpenAIRE

    Han CH; Hwang HS; Lee YJ; Lee SN; Abanes JJ; Lee BH

    2016-01-01

    Chang Hyun Han,1,* Hwa Soo Hwang,2,* Young Joon Lee,3 Sang Nam Lee,4 Jane J Abanes,5 Bong Hyo Lee6 1Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, 2Chims-Saengvit Oriental Medicine Clinic, Seoul, 3Department of Preventive Korean Medicine, 4Department of Qigong, College of Korean Medicine, Daegu Haany University, Gyeongsangbuk-do, South Korea; 5Daniel K Inouye Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; 6Depa...

  15. Supplement to the Proceedings of the Annual Symposium on Frequency Control (42nd) Held in Baltimore, Maryland on 1-3 June 1988. Subject and Author Index for the Proceedings for the 10th to 42nd Symposia on Frequency Control and Symposium Historical Information, 1946-1988

    Science.gov (United States)

    1988-01-01

    accomplish the Army’s mission in astronomical problems of expanding and mod- communication on a timely basis." ernizing an industry capable of producing ...142 Factors Covering the Hydrothermal 1-26-92 The Growth of Lithium Tantalate, a Formation of Cristobalite and Quartz Wideband, Low Impedance and Zero...40-32 A Radiation Growth Study of Acoustic Autoclaves - C.B. Sawyer and D.R. Loss Related Defects in Alpha-Quartz Kinloch - J.J. Martin, H.B. Hwang and

  16. A New Batch Verifying Scheme for Identifying Illegal Signatures

    Institute of Scientific and Technical Information of China (English)

    Adrian Atanasiu

    2013-01-01

    The concept of batch verifying multiple digital signatures is to find a method by which multiple digital signatures can be verified simultaneously in a lower time complexity than separately verifying all the signatures.In this article,we analyze the complexity of the batch verifying schemes defined by Li,Hwang and Chen in 2010,and propose a new batch verifying multiple digital signature scheme,in two variants:one for RSA-by completing the Harn's schema with an identifying illegal signatures algorithm,and the other adapted for a modified Elliptic Curve Digital Signature Algorithm protocol.

  17. Identifying microRNAs that Regulate Neuroblastoma Cell Differentiation

    Science.gov (United States)

    2014-09-01

    Respondents should be aware that notwithstanding any other provision of law , no person shall be subject to any penalty for failing to comply with a...or  an  offer  for  sale)  may  compromise  patent  rights.    After  public  disclosure,  US  patent   law ...O’Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA

  18. Simulated Assessment of Interference Effects in Direct Sequence Spread Spectrum (DSSS) QPSK Receiver

    Science.gov (United States)

    2014-03-27

    such as Wi-Fi, Bluetooth, and Zigbee . Special attention is focused on wireless sensor networks, cellular telephony, wireless tactical military...Proceedings of the Fourth ACM Conference on Wireless Network Security , New York, NY, USA, 2011, WiSec ’11, pp. 47–52, ACM. [18] Y. Bo, Sh. Gao-ping, and S...November 2010. [21] J. Guo H.Wang and Z. Wang, “Evaluation of Security for DSSS Under Repeater Jamming,” in IEEE International Conference on Communications

  19. What, who or where? Rejoinder to "identifying research topic development in Business and Management education research using legitimation code theory"

    OpenAIRE

    Anne-Wil HARZING

    2016-01-01

    Arbaugh, Fornaciari and Hwang (2016) use citation analysis – with Google Scholar as their source of citation data – to track the development of Business and Management Education research by studying the field’s 100 most highly cited articles. In their article, the authors distinguish several factors that might impact on an article’s level of citations: the topic it addresses, the profile of the author(s) who wrote it and the prominence of the journal that the article is published in. Alth...

  20. Inorganic Halogen Oxidizer Research

    Science.gov (United States)

    1975-02-26

    Fessenden and R. H. Schüler, J. Chem. Phys., 43, 2704 (1965). (II) J. Maruani, J.A.R. Coope, and C A. McDowell, Mol. Phys., 18, 105 (1970). (12) J...14) W. E. Tolberg, private eommuncation. (15) R. W. Fessenden , J. Chem. Phys., 37, 747 (1902). (l’\\) J.A.R. Coope, Chem. Phys. Letts., 3, 589...W. Fessenden and 11. II. Schüler, J. Chem. Phys., 45, 1845 (i960). (20) F. G. Herring, J. II. Hwang and W. C. Lin, J. Phys. Chem.» 71, 2080 (1907

  1. The 10000th Domestic Volvo Excavators%沃尔沃中国产第一万台挖掘机"特写"

    Institute of Scientific and Technical Information of China (English)

    薛学伟

    2010-01-01

    @@ 5月6日,沃尔沃建筑设备(VOLVOCE)在华发展的又一里程碑--中国本土生产的第-万台挖掘机正式下线.沃尔沃建筑设备全球总裁Olof Persson.亚太区总裁Eberhard Wedekind,亚太运营总裁Suk wisoo和中国市场总裁罗东先生与中国员工代表.来自全国工程机械行业媒体记者一同见证了这个隆重的时刻.沃尔沃在中国第-万台挖掘机顺利下线,标志着沃尔沃建筑设备在华发展已达到一个新的高度,进入快速增长的通道.

  2. Converting Nonclassicality into Entanglement.

    Science.gov (United States)

    Killoran, N; Steinhoff, F E S; Plenio, M B

    2016-02-26

    Quantum mechanics exhibits a wide range of nonclassical features, of which entanglement in multipartite systems takes a central place. In several specific settings, it is well known that nonclassicality (e.g., squeezing, spin squeezing, coherence) can be converted into entanglement. In this work, we present a general framework, based on superposition, for structurally connecting and converting nonclassicality to entanglement. In addition to capturing the previously known results, this framework also allows us to uncover new entanglement convertibility theorems in two broad scenarios, one which is discrete and one which is continuous. In the discrete setting, the classical states can be any finite linearly independent set. For the continuous setting, the pertinent classical states are "symmetric coherent states," connected with symmetric representations of the group SU(K). These results generalize and link convertibility properties from the resource theory of coherence, spin coherent states, and optical coherent states, while also revealing important connections between local and nonlocal pictures of nonclassicality.

  3. Journal Of The Korean Hydrogen Energy Society 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-11-15

    This book is the Journal of the Korean hydrogen energy society, which includes study on the improvement of the electrochemical characteristics of surface-modified V-Ti-Cr alloy by Ball-milling by Kim, Jin Ho; Lee, Sang Min; Lee, Ho; Lee, Paul S. and Lee, Jai Young, hydrogen generation from water using cds-zns photocatalysts by Heo, Gwi Suk, characteristics of Y-Hx Film by Cho, Young Sin; Kim, Sun Hee, and effect of Cu powder as a compacting material on the discharge characteristics of the negative electrode of Ni-MH battery by Jung, J. H.; Han, Y. S.; Yu, J. S.; Jang, K. J.; Lee, J. Y.

  4. MECHANICAL PROPERTIES ANALYSIS AND RELIABILITY ASSESSMENT OF LAMINATED VENEER LUMBER (LVL HAVING DIFFERENT PATTERNS OF ASSEMBLY

    Directory of Open Access Journals (Sweden)

    Bing Xue,

    2012-02-01

    Full Text Available Laminated Veneer Lumber (LVL panels made from poplar (Populus ussuriensis Kom. and birch (Betula platyphylla Suk. veneers were tested for mechanical properties. The effects of the assembly pattern on the modulus of elasticity (MOE and modulus of rupture (MOR of the LVL with vertical load testing were investigated. Three analytical methods were used: composite material mechanics, computer simulation, and static testing. The reliability of the different LVL assembly patterns was assessed using the method of Monte-Carlo. The results showed that the theoretical and ANSYS analysis results of the LVL MOE and MOR were very close to those of the static test results, and the largest proportional error was not greater than 5%. The veneer amount was the same, but the strength and reliability of the LVL made of birch veneers on the top and bottom was much more than the LVL made of poplar veneers. Good assembly patterns can improve the utility value of wood.

  5. Generalized semi-analytical solutions to multispecies transport equation coupled with sequential first-order reaction network with spatially or temporally variable transport and decay coefficients

    Science.gov (United States)

    Suk, Heejun

    2016-08-01

    This paper presents a semi-analytical procedure for solving coupled the multispecies reactive solute transport equations, with a sequential first-order reaction network on spatially or temporally varying flow velocities and dispersion coefficients involving distinct retardation factors. This proposed approach was developed to overcome the limitation reported by Suk (2013) regarding the identical retardation values for all reactive species, while maintaining the extensive capability of the previous Suk method involving spatially variable or temporally variable coefficients of transport, general initial conditions, and arbitrary temporal variable inlet concentration. The proposed approach sequentially calculates the concentration distributions of each species by employing only the generalized integral transform technique (GITT). Because the proposed solutions for each species' concentration distributions have separable forms in space and time, the solution for subsequent species (daughter species) can be obtained using only the GITT without the decomposition by change-of-variables method imposing the limitation of identical retardation values for all the reactive species by directly substituting solutions for the preceding species (parent species) into the transport equation of subsequent species (daughter species). The proposed solutions were compared with previously published analytical solutions or numerical solutions of the numerical code of the Two-Dimensional Subsurface Flow, Fate and Transport of Microbes and Chemicals (2DFATMIC) in three verification examples. In these examples, the proposed solutions were well matched with previous analytical solutions and the numerical solutions obtained by 2DFATMIC model. A hypothetical single-well push-pull test example and a scale-dependent dispersion example were designed to demonstrate the practical application of the proposed solution to a real field problem.

  6. Web-of-Objects (WoO-Based Context Aware Emergency Fire Management Systems for the Internet of Things

    Directory of Open Access Journals (Sweden)

    Zia Ush Shamszaman

    2014-02-01

    Full Text Available Recent advancements in the Internet of Things (IoT and the Web of Things (WoT accompany a smart life where real world objects, including sensing devices, are interconnected with each other. The Web representation of smart objects empowers innovative applications and services for various domains. To accelerate this approach, Web of Objects (WoO focuses on the implementation aspects of bringing the assorted real world objects to the Web applications. In this paper; we propose an emergency fire management system in the WoO infrastructure. Consequently, we integrate the formation and management of Virtual Objects (ViO which are derived from real world physical objects and are virtually connected with each other into the semantic ontology model. The charm of using the semantic ontology is that it allows information reusability, extensibility and interoperability, which enable ViOs to uphold orchestration, federation, collaboration and harmonization. Our system is context aware, as it receives contextual environmental information from distributed sensors and detects emergency situations. To handle a fire emergency, we present a decision support tool for the emergency fire management team. The previous fire incident log is the basis of the decision support system. A log repository collects all the emergency fire incident logs from ViOs and stores them in a repository.

  7. Web-of-Objects (WoO)-based context aware emergency fire management systems for the Internet of Things.

    Science.gov (United States)

    Shamszaman, Zia Ush; Ara, Safina Showkat; Chong, Ilyoung; Jeong, Youn Kwae

    2014-02-13

    Recent advancements in the Internet of Things (IoT) and the Web of Things (WoT) accompany a smart life where real world objects, including sensing devices, are interconnected with each other. The Web representation of smart objects empowers innovative applications and services for various domains. To accelerate this approach, Web of Objects (WoO) focuses on the implementation aspects of bringing the assorted real world objects to the Web applications. In this paper; we propose an emergency fire management system in the WoO infrastructure. Consequently, we integrate the formation and management of Virtual Objects (ViO) which are derived from real world physical objects and are virtually connected with each other into the semantic ontology model. The charm of using the semantic ontology is that it allows information reusability, extensibility and interoperability, which enable ViOs to uphold orchestration, federation, collaboration and harmonization. Our system is context aware, as it receives contextual environmental information from distributed sensors and detects emergency situations. To handle a fire emergency, we present a decision support tool for the emergency fire management team. The previous fire incident log is the basis of the decision support system. A log repository collects all the emergency fire incident logs from ViOs and stores them in a repository.

  8. Tracking growth hormone abuse in sport: performance of marker proteins in a controlled setting.

    Science.gov (United States)

    Bosch, J; Such-Sanmartín, G; Segura, J; Gutiérrez-Gallego, R

    2012-10-01

    Human growth hormone (hGH) abuse in sport is a challenge at present. The current strategy used, known as direct method, is based on the quantification of hGH variants in serum. An alternative strategy, known as indirect method, focuses on serum markers such as insulin-like growth factor I (IGF-I) and procollagen type III N-terminal propeptide (P-III-NP). The indirect method allows a longer window of detection (WOO) of hGH abuse. To evaluate the performance of the indirect method, in parallel to the direct method, a clinical trial with recombinant hGH (rhGH) was conducted on healthy male subjects during 7 days (0.026 mg(-1) kg(-1) person(-1) day(-1)). The data were fit to the discriminant formula proposed in the previously published GH-2000 project. The low sensitivity of the scores, judged from the high number of false negative outcomes, imposed a new discriminant analysis, standarised using local population subjects demographically similar to the ones of the study. The sensitivity of the method significantly increased, highlighting the importance of the standardisation. The indirect method allowed extended window of opportunity (WOO), although two false positive evaluations were observed derived from elevated basal IGF-I and P-III-NP concentrations stressing the need for an independent confirmation method. When direct and indirect methods were combined the best selectivity and sensitivity were achieved.

  9. Which is the most accurate formula to estimate fetal weight in women with severe preterm preeclampsia?

    Science.gov (United States)

    Geerts, Lut; Widmer, Tania

    2011-02-01

    To identify the most accurate formula to estimate fetal weight (EFW) from ultrasound parameters in severe preterm preeclampsia. In a prospective study, serial ultrasound assessments were performed in 123 women with severe preterm preeclampsia. The EFW, calculated for 111 live born, normal, singleton fetuses within 7 days of delivery using 38 published formulae, was compared to the actual birth weight (ABW). Accuracy was assessed by correlations, mean (absolute and signed) (%) errors, % correct predictions within 5-20% of ABW and limits of agreement. Accuracy was highly variable. Most formulae systematically overestimated ABW. Five Hadlock formulae utilizing three or four variables and Woo 3 formula had the highest accuracy and did not differ significantly (mean absolute % errors 6.8-7.2%, SDs 5.3-5.8%, > 75% of estimations within 10% of ABW and 95% limits of agreement between -18/20% and +14/15%). They were not negatively affected by clinical variables but had some inconsistency in bias over the ABW range. All other formulae, including those targeted for small, preterm or growth restricted fetuses, were inferior and/or affected by multiple clinical variables. In this GA window, Hadlock formulae using three or four variables or Woo 3 formula can be recommended.

  10. All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 11. (Aitkin, Minnesota-Zephyr Cove, Nevada).

    Science.gov (United States)

    1988-01-01

    l 4 I-40(ON 00-4 ww 0C0 00 00 M44 4 0 0 4)0 -- ac~0 0 N 0 1 0-4 10 woo qt WMV .4r-- ~ x~ m m 3m X M -4 2011 04T " f0(0ON AZ 0.-44w 00 O ). 00 0 0...mmomm cm m WIWOW 1 (0 (0(0 r w ow w0 ww( occccc wwvW wc w0 I WOWr IG U Qc 00 woo coc 00 coc cecoao coco-gceOuau 0 sWOt I "t 00 00 00 00 0 00 0000 00...4NNCN*N GW0 40 -INN IN IN C 4 4 C4 L4 (0 4(0004 1 3: nmIn InIn oIn UU, 3 P.- -I--r- f-. 3:0) 3: 0 :3: 000 3m :30 300 c : c 1(00004 I t , r.- - , r. 1

  11. In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial.

    Science.gov (United States)

    Konstantinidou, Valentini; Covas, Maria-Isabel; Muñoz-Aguayo, Daniel; Khymenets, Olha; de la Torre, Rafael; Saez, Guillermo; Tormos, Maria del Carmen; Toledo, Estefania; Marti, Amelia; Ruiz-Gutiérrez, Valentina; Ruiz Mendez, Maria Victoria; Fito, Montserrat

    2010-07-01

    The aim of the study was to assess whether benefits associated with the traditional Mediterranean diet (TMD) and virgin olive oil (VOO) consumption could be mediated through changes in the expression of atherosclerosis-related genes. A randomized, parallel, controlled clinical trial in healthy volunteers (n=90) aged 20 to 50 yr was performed. Three-month intervention groups were as follows: 1) TMD with VOO (TMD+VOO), 2) TMD with washed virgin olive oil (TMD+WOO), and 3) control with participants' habitual diet. WOO was similar to VOO, but with a lower polyphenol content (55 vs. 328 mg/kg, respectively). TMD consumption decreased plasma oxidative and inflammatory status and the gene expression related with both inflammation [INF-gamma (INFgamma), Rho GTPase-activating protein15 (ARHGAP15), and interleukin-7 receptor (IL7R)] and oxidative stress [adrenergic beta(2)-receptor (ADRB2) and polymerase (DNA-directed) kappa (POLK)] in peripheral blood mononuclear cells. All effects, with the exception of the decrease in POLK expression, were particularly observed when VOO, rich in polyphenols, was present in the TMD dietary pattern. Our results indicate a significant role of olive oil polyphenols in the down-regulation of proatherogenic genes in the context of a TMD. In addition, the benefits associated with a TMD and olive oil polyphenol consumption on cardiovascular risk can be mediated through nutrigenomic effects.

  12. Estimates of population parameters and consumption/biomass ratio for fishes in reservoirs, Paraná State, Brazil

    Directory of Open Access Journals (Sweden)

    Éder André Gubiani

    Full Text Available Consumption, natural mortality, and growth are important parameters for the construction for both fisheries and ecosystems models. We estimated k (growth constant of the von Bertalanffy's function, Loo 1(asymptotic length, Woo (asymptotic weight, Ar (caudal fin index, M (natural mortality, and Q/B (consumption/biomass ratio for several fish species inhabiting reservoirs. We explored possible relationships among these parameters for 135 fish species sampled in thirty reservoirs in the State of Paraná, southern Brazil. Maximum length (Lmax varied from 2.60 to 79.00 cm, Loo from 2.73 to 85.05 cm, Woo from 0.23 to 9,490.26 g, k from 0.01 to 2.38 yr-1, Ar from 0.03 to 3.60, M from 0.16 to 2.82 yr-1, and Q/B from 3.31 to 67.18. Significant correlations were observed between most pairs of parameters, except for Ar and k, Ar and Loo , and for M and Q/B. The estimates presented here may be useful for constructing Ecopath models, both in Brazil and other tropical regions, where the use of ecosystem modeling is growing.

  13. The Process of Self-Cultivation and the Mandala Model of the Self.

    Science.gov (United States)

    Wu, Meiyao

    2017-01-01

    In his Mandala model of the self, Taiwanese scholar Kwang-Kuo Hwang sees each human being as a combination or intersection of private individual and social person, and also of knowledge and action. To further elaborate the model-with a particular emphasis on teaching/learning, the development of the ideal self and spiritual transcendence-this article will explore the psychological process of self-cultivation in the light of traditional Confucian thinking, which means keeping a balance between inner/outer and self/other. The Neo-Confucian thinker Zhongsha Mou's theories of "the awareness of unexpected developments" and his meditation/cognitive thinking opposition will also be discussed. The analyzed sources will include the traditional Confucian classics (the Four Books and Liji, or Classic of Rites) and especially the "Lessons for Learning (Xue-Ji)" in the Classic of Rites (Liji), along with the relevant textual research. Based upon a cultural-semantic analysis of these classics as well as of Hwang's central ideas, the author attempts to further conceptualize the process of cultivating the ideal self in Confucian education.

  14. Default Spread dan Term Spread sebagai Variabel Proxy Siklus Bisnis pada Model Fama-French

    Directory of Open Access Journals (Sweden)

    Edwin Hendra

    2015-08-01

    Full Text Available This research aims to apply the Fama-French models and test the effect of alternative variable of bond yield spread, default spread (RBBB – RAAA and RAAA – RF, and the term spread (RSUN10-RSUN1, as proxy variables of the business cycle, in IDX stock data during 2005-2010. Four types of asset pricing models tested are Sharpe-Lintner CAPM, Fama-French models, Hwang et al.model, and hybrid model. The results showed that the size effect and value effect has an impact on excess stock returns. Slopes of market beta, SMB, and HML are more sensitive to stock big size and high B / M. Default spreads and term spreads in Hwang et al. model can explain the value effect, and weakly explain the size effect, meanwhile the power of explanation disappeared on Hybrid models. Based on the assessment adjusted R2 and the frequency of rejection of non-zero alpha, is found that the hybrid model is the most suitable model.  

  15. 改进抵御攻击算法的电子公文收发系统%Sending and Receiving Electronic Document System Based on Attack Resistance Algorithm

    Institute of Scientific and Technical Information of China (English)

    胡洋; 苏琳

    2011-01-01

    对电子公文收发系统的抵御攻击能力着手研究,分析并使用智能卡加强电子公文的安全管理.首先介绍了Hwang-Li方案抵御攻击的原理,分析其安全性的不足,并提出改进的方案,验证了抵御几种攻击的有效性.最后,在我校的公文收发系统中进行实践性检验.%For sending and receiving electronic document System, the capablitity to resist attack is researched. The smart card is used to strengthen the safety management about electronic document. First, the principle about Hwang-L scheme to resist attack is introduced in this paper. The shortcomings of security system is analyzed, and improved scheme is brought out. The improved scheme is enumerated to many kinds forms about attack to be analyzed. Finally, the inspection was carried out in sending and receiving electronic document System in our college.

  16. Extended yrast level schemes in ^121,123Cd

    Science.gov (United States)

    Walters, W. B.; Chiara, C. J.

    2010-11-01

    New level structures for ^121,123Cd will be presented that were determined in the study of the ^64Ni- and ^76Ge-induced fission of ^238U at Gammasphere [1]. A number of transitions were previously observed by Hwang et al. from which yrast levels were identified with maximum proposed spins of 27/2- and 23/2- in ^121,123Cd, respectively [2]. If the additional transitions have stretched E2 multipolarity, these level structures would be extended to 31/2- at 4083 keV, and 35/2- at 5365 keV in ^121,123Cd, respectively. These level sequences will be compared to existing levels in the lighter odd-mass Cd nuclei and the isomeric structures and calculations in the heavier odd-mass Cd nuclei.[4pt] [1] C. J. Chiara, I. Stefanescu, A. A. Hecht, R. V. F. Janssens, W. B. Walters, R. Broda, M. P. Carpenter, B. Fornal, G. Gúrdal, C. R. Hoffman, N. Hoteling, B. P. Kay, F. G. Kondev, W. Kr'olas, T. Lauritsen, C. J. Lister, E. A. McCutchan, T. Pawlat, D. Seweryniak, N. Sharp, J. R. Stone, N. J. Stone, X. Wang, A. Wóhr, J. Wrzesinski, S. Zhu, to be submitted for publication in Phys. Rev. C.[0pt] [2] J. K. Hwang et al., J. Phys. G: Nucl. Part. Phys. 28, L9 (2002).

  17. The Process of Self-Cultivation and the Mandala Model of the Self

    Science.gov (United States)

    Wu, Meiyao

    2017-01-01

    In his Mandala model of the self, Taiwanese scholar Kwang-Kuo Hwang sees each human being as a combination or intersection of private individual and social person, and also of knowledge and action. To further elaborate the model—with a particular emphasis on teaching/learning, the development of the ideal self and spiritual transcendence—this article will explore the psychological process of self-cultivation in the light of traditional Confucian thinking, which means keeping a balance between inner/outer and self/other. The Neo-Confucian thinker Zhongsha Mou's theories of “the awareness of unexpected developments” and his meditation/cognitive thinking opposition will also be discussed. The analyzed sources will include the traditional Confucian classics (the Four Books and Liji, or Classic of Rites) and especially the “Lessons for Learning (Xue-Ji)” in the Classic of Rites (Liji), along with the relevant textual research. Based upon a cultural-semantic analysis of these classics as well as of Hwang's central ideas, the author attempts to further conceptualize the process of cultivating the ideal self in Confucian education1. PMID:28174544

  18. Geographic List of Prime Contract Awards. Oct 1992-Sep 1993. FY 1993. (Adelanto, California-Yuba County, California). Part 2

    Science.gov (United States)

    1994-03-01

    00m 1 w o- ?, MP, a)m (DC -IttiC) o - 0-Ln rý0 LL OLA Cori ton’- a1101 0 v ifiO4Njm 0lmi-r. CI a) wt 0m Na, Lm-4,v C 4-L C-.a) N Ln a, tDo 4a, - 11 1 I...II ’ CIclo -’ II -. 000000000000000000000000000000000000000000000000 /1 fA.4 I Co 0 1 ) ncnu ( V n iOnO ( ) n r u ) ncnv c O n Av)v (n nt/ n r L i n nV...c cli c c)) Cori 11 w I Mov 11 woo wo wo (1) 0 WOOOOOOOO- a) o 0 Q - 0 0 a) - w 0 11 u I C13 0 v If 13 m (n -0 (\\I ’D v -0 m mmmmmmmmcnc1j -Dvv 13 CQ m

  19. Investigation and Evaluation of Geopressured-Geothermal Wells; Detailed Completion Prognosis for Geopressured-Geothermal Well of Opportunity Prospect No.6; Beulah Simon No. 2 Well

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-04-06

    This well of opportunity (WOO) geopressured-geothermal prospect has been drilled to 15,265 feet by Southport Exploration, Inc. (Southport) as the Beulah Simon No. 2 Well. The well is located in Section 26, T11S, R2E, Vermilion Parish, Louisiana, approximately four miles northeast of the town of Kaplan. The wellsite is shown on the enclosed section of USGS topographic sheet, ''Lafayette, La.'', and is accessible by State Highway 13 from Interstate Highway 10. The well was drilled approximately one mile east of the Southport et al. Beulah Simon No. 1 Well in the Cossinade Field. The Beulah Simon No. 1 Well is producing natural gas from a zone which is separate and distinct from the target reservoir in the No. 2 Well.

  20. “老虎”的9月之旅

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    近日,老虎·伍兹(Tiger Woo- ds)宣布将参加今年9月14日-17日在英格兰温特沃斯球场举行的HSBC世界比洞锦标赛(HSBC World Match Play Championship)。随后,他将直接奔赴爱尔兰K俱乐部,参加一周后举行的2006年"莱德杯",开始艰难的"洗刷耻辱"的自卫战斗。在"老虎"出战的4届"莱德杯"中,胜了7场,输了11场,打平2场。作为世界离尔夫的霸主,"老虎"在"莱

  1. Prime Contract Awards Alphabetically by Contractor, By State or Country, and Place, FY 84. Part 2. (Bay Area Controls - Cirtech Corporation).

    Science.gov (United States)

    1984-01-01

    N MOMO )0)- _j OJ D1 0 0 W) ----------------- WI IiiCC4Z --- <ɜ Wic) U N (D (((( (0.4L 0 Ir 0 ’CD CmsWNNNNwix 0 N K0 :)_ C DOD0000-)CDOD))) a...c 0q ) i) I) to q caI o w~ 0q 90 - V)V * WI co 0 , ( t 0 cor- CYCY J~0 OMOtn M- MoMO c I -, i N ) C) (1) C) NMN IOK )Mr-0q CII ) if) )0C) In 1--’ 0...8217 0 00 wo 00 0 woo 0ɘ 00<<ᝰ 0 >- IC1. U. MOMO 0o0o < 0 M00 t 󈧄C ’ N 0)0) a- Nl N N INNcj---- - co 0M 0. < 004 V)In crt 004 7v F- 0 0- 0 0 40 4 0

  2. Developing security protocols in χ-Spaces

    DEFF Research Database (Denmark)

    Crazzolara, Federico; Milicia, Giuseppe

    2002-01-01

    of formal protocol verification. Verification, however, is usually carried out on an abstract model not at all related with a protocol’s implementation. Experience shows that security breaches introduced in implementations of successfully verified models are rather common. The χ-Spaces framework...... is an implementation of SPL (Security Protocol Language), a formal model for studying security protocols. In this paper we discuss the use of χ-Spaces as a tool for developing robust security protocol implementations. To make the case, we take a family of key-translation protocols due to Woo and Lam and show how χ......It is of paramount importance that a security protocol effectively enforces the desired security requirements. The apparent simplicity of informal protocol descriptions hides the inherent complexity of their interactions which, often, invalidate informal correctness arguments and justify the effort...

  3. Statistical mechanics of dilute liquid mixtures of He3 in He4

    Science.gov (United States)

    Jackson, H. W.

    1982-01-01

    The Woo-Tan-Massey quantum-mechanical theory of dilute mixtures of He-3 in liquid He-4 is extended to incorporate superfluid flow. Then statistical-mechanical principles are employed to find explicit formulas for thermodyanmic and hydrodynamic properties of mixtures, such as internal energy, free energy, entropy, pressure, chemical potential, and normal-fluid and superfluid densities. This paper is the first in a planned series that applies methods originally developed for pure liquid He-4 to dilute mixtures as a means of establishing a comprehensive theory that includes a theoretical bridge between a microscopic description of the mixtures and a hydrodynamic two-fluid model. Ultimately effects of applied electric and magnetic fields on dilute solutions are also planned to be treated.

  4. The Atacama Cosmology Telescope: The Receiver and Instrumentation

    Science.gov (United States)

    Swetz, D. S.; Ade, P. A. R.; Amiri, M.; Appel, J. W.; Burger, B.; Devlin, M. J.; Dicker, S. R.; Doriese, W. B.; Essinger-Hileman, T.; Fisher, R. P.; Fowler, J. W.; Halpern, M.; Hasselfield, M.; Hilton, G. C.; Hincks, A. D.; Irwin, K. D.; Jarosik, N.; Kaul, M.; Klein, J.; Marsden, D.; Thornton, R.; Mauskopf, P.; Niemack, M. D.; Page, L. A.; Parker, L.

    2010-01-01

    The Atacama Cosmology Telescope was designed to measure small-scale anisotropies in the Cosmic Microwave Background and detect galaxy clusters through the Sunyaev-Zel'dovich effect. The instrument is located on Cerro Taco in the Atacama Desert, at an altitude of 5190 meters. A six-met.er off-axis Gregorian telescope feeds a new type of cryogenic receiver, the Millimeter Bolometer Array Camera. The receiver features three WOO-element arrays of transition-edge sensor bolometers for observations at 148 GHz, 218 GHz, and 277 GHz. Each detector array is fed by free space mm-wave optics. Each frequency band has a field of view of approximately 22' x 26'. The telescope was commissioned in 2007 and has completed its third year of operations. We discuss the major components of the telescope, camera, and related systems, and summarize the instrument performance.

  5. New Semantic Model for Authentication Protocols in ASMs

    Institute of Scientific and Technical Information of China (English)

    Rui Xue; Deng-Guo Feng

    2004-01-01

    A new semantic model in Abstract State Model(ASM)for authentication protocols is presented.It highlights the Woo-Lam's ideas for authentication,which is the strongest one in Lowe's definition hierarchy for entity authentication.Apart from the flexible and natural features in forming and analyzing protocols inherited from ASM,the model defines both authentication and secrecy properties explicitly in first order sentences as invariants.The process of proving security properties with respect to an authentication protocol blends the correctness and secrecy properties together to avoid the potential flaws which may happen when treated separately.The security of revised Helsinki protocol is shown as a case study.The new model is different from the previous ones in ASMs.

  6. Hõimlane verejõe tagant: Saami muinaslood tootempõhjapõdrast. III

    Directory of Open Access Journals (Sweden)

    Enn Ernits

    1998-01-01

    Full Text Available There are two motifs in stories about taking a wife: wooing and the visit of the fater- and mother-in-law. The wooers are either animals or people in animal costumes. Unlike in the first subtype, the wooers are active. Animals obviously represent totems.One variant of a Turja fairytale has obvious infulences from the Indo-European wonder-fairytale "Frog the Princess" (AT 402 where the proposer is given difficult tasks and where the wife burns her husband's skin. In another variant, married girls leave their parents in zoomorphic form. In a couple of variants, the mother wants to wed her younger daughter to her totem animal.The two variants of the third subtype represent a contamination of stories of a reindeer and dog marrying and its motifs are not clear. In both variants, future brides cross a taboo, for which they are turned into stone.

  7. Estimates of population parameters and consumption/biomass ratio for fishes in reservoirs, Paraná State, Brazil

    Directory of Open Access Journals (Sweden)

    Éder André Gubiani

    2012-01-01

    Full Text Available Consumption, natural mortality, and growth are important parameters for the construction for both fisheries and ecosystems models. We estimated k (growth constant of the von Bertalanffy's function, Loo 1(asymptotic length, Woo (asymptotic weight, Ar (caudal fin index, M (natural mortality, and Q/B (consumption/biomass ratio for several fish species inhabiting reservoirs. We explored possible relationships among these parameters for 135 fish species sampled in thirty reservoirs in the State of Paraná, southern Brazil. Maximum length (Lmax varied from 2.60 to 79.00 cm, Loo from 2.73 to 85.05 cm, Woo from 0.23 to 9,490.26 g, k from 0.01 to 2.38 yr-1, Ar from 0.03 to 3.60, M from 0.16 to 2.82 yr-1, and Q/B from 3.31 to 67.18. Significant correlations were observed between most pairs of parameters, except for Ar and k, Ar and Loo , and for M and Q/B. The estimates presented here may be useful for constructing Ecopath models, both in Brazil and other tropical regions, where the use of ecosystem modeling is growing.O consumo, a mortalidade natural e as estimativas de crescimento são parâmetros importantes para a construção de modelos pesqueiros e ecossistêmicos. Dessa forma, neste trabalho foram calculados os parâmetros k (constante de crescimento da equação de von Bertalanffy, Loo (comprimento assintótico, Woo (peso assintótico, Ar (índice da nadadeira caudal, M (mortalidade natural e Q/B (consumo/biomassa para peixes em reservatórios. Além disso, foram exploradas possíveis relações entre esses parâmetros para 135 espécies de peixes amostradas em 30 reservatórios no estado do Paraná, sul do Brasil. O comprimento máximo (Lmax variou de 2,60 a 79,00 cm, Loo de 2,73 a 85,05 cm, Woo de 0,23 a 9.490,26 g, k de 0,01 a 2,38 ano-1, Ar de 0,03 a 3,60, M de 0,16 a 2,82 ano-1, e Q/B de 3,31 a 67,18. Correlações significativas foram observadas entre todos os pares de parâmetros, exceto para Ar e k, Ar e Loo e para M e Q/B. As estimativas

  8. All Prime Contract Awards by State or Country, Place, and Contractor, FY 88. Part 12. (Amherst, New Hampshire-White Sands Missile Range, New Mexico).

    Science.gov (United States)

    1988-01-01

    0m N -4mi 0mm0)) - m)0) ) 0 )40) I 0) c0) 0)40) mm 4 IWOM’ o ( V M ~ q I 04-t- *q 0() t-r*-t- -I4t-tP V-4 41 -4 V- .mrVI CLSI WOO’ I M’ V’) M M M’ C’C...4 00 41 400C0 40 43-400 IN " f0 1 O04 1404 4-0 (0 -t 0 r- CY) 0 0 0nI~0 O 4 4𔃾 N 0-4-I-I 0 ’) OCIC𔃾 -IN 0-4 C(4 CNNN 0 XZ-x I .0ig-..00000)))))) C24

  9. Of money and trust in medical care redux.

    Science.gov (United States)

    Lexchin, Joel

    2012-01-01

    Should we be concerned about financial conflicts of interest (COI) between doctors and the pharmaceutical industry? Some people will say no as there are clearly doctors who celebrate the relationship. Others say that it does not matter to patients, but the evidence says otherwise. Financial COI is different from other types of conflicts because it is voluntary and can be refused. Finally, it is not just the large gifts that are a problem, the small ones also create a "gift relationship." Drug companies know about this and spend billions on promotion with good effect from their point of view. Companies also woo doctors who honestly hold pro-industry points of view to speak on behalf of the companies. There are still multiple examples of financial COI, and although there are isolated examples of improvement, this is still an area of deep concern.

  10. A rare case of concurrent signet-ring carcinoma of breast and microangiopathic hemolytic anemia†

    Science.gov (United States)

    Lara, Kelly; Bae, Esther; Park, Hanna; Hussain, Farabi

    2016-01-01

    Microangiopathic hemolytic anemia (MAHA) can be an uncommon presentation of an underlying malignancy, most often due to signet-ring cell carcinoma (SRCC). Additionally, pure SRCC in a breast primary-tumor comprises <2% of all breast cancers (Shin SY, Park H, Chae SW, Woo HY. Microangiopathic hemolytic anemia as the first manifestation of metastatic signet-ring cell carcinoma of unknown origin: a case report and review of literature. Kor J Lab Med 2011;31:157–61). To the best of our knowledge, the combination of these two entities, pure breast primary SRCC along with MAHA, has not been reported. Here, we present such a rare case. We also evaluate the current literature regarding this and similar disease processes, of which evidence is scarce and further research is needed. PMID:27587305

  11. Learning to recognize volcanic non-eruptions

    Science.gov (United States)

    Poland, Michael P.

    2010-01-01

    An important goal of volcanology is to answer the questions of when, where, and how a volcano will erupt—in other words, eruption prediction. Generally, eruption predictions are based on insights from monitoring data combined with the history of the volcano. An outstanding example is the A.D. 1980–1986 lava dome growth at Mount St. Helens, Washington (United States). Recognition of a consistent pattern of precursors revealed by geophysical, geological, and geochemical monitoring enabled successful predictions of more than 12 dome-building episodes (Swanson et al., 1983). At volcanic systems that are more complex or poorly understood, probabilistic forecasts can be useful (e.g., Newhall and Hoblitt, 2002; Marzocchi and Woo, 2009). In such cases, the probabilities of different types of volcanic events are quantified, using historical accounts and geological studies of a volcano's past activity, supplemented by information from similar volcanoes elsewhere, combined with contemporary monitoring information.

  12. Shock wave science and technology reference library

    CERN Document Server

    2009-01-01

    This book is the second of several volumes on solids in the Shock Wave Science and Technology Reference Library. These volumes are primarily concerned with high-pressure shock waves in solid media, including detonation and high-velocity impact and penetration events. Of the four extensive chapters in this volume, the first two describe the reactive behavior of condensed phase explosives, - Condensed-Phase Explosives: Shock Initiation and Detonation Phenomena (SA Sheffield and R Engelke) - First Principles Molecular Simulations of Energetic Materials at High-Pressures (F Zhang, S Alavi, and TK Woo), and the remaining two discuss the inert, mechanical response of solid materials. - Combined Compression and Shear Plane Waves (ZP Tang and JB Aidun), and - Dynamic Fragmentation of Solids (D Grady). All chapters are each self-contained, and can be read independently of each other. They offer a timely reference, for beginners as well as professional scientists and engineers, on the foundations of detonation phenomen...

  13. Trypanosoma vivax infection dynamics in a cattle herd maintained in a transition area between Pantanal lowlands and highlands of Mato Grosso do Sul, Brazil Dinâmica de infecção de Trypanosoma vivax em rebanho bovino mantido numa área de transição entre o Pantanal e o planalto de Mato Grosso do Sul

    Directory of Open Access Journals (Sweden)

    Charles F. Martins

    2008-01-01

    Full Text Available Trypanosoma vivax outbreaks in beef cattle in the Pantanal region of Mato Grosso do Sul state, Brazil, causes relevant economical impact due to weight loss, abortion and mortality. Cattle moved from the Pantanal to adjacent areas of this ecosystem for breeding and fattening is a common feature. Therefore an epidemiological study on breeding cows in the transition area between Pantanal lowland and adjacent highlands of Mato Grosso do Sul was performed to determine the T. vivax infection dynamics and outbreak risk. Three experimental groups were formed: Group 1 consisted of cows parasitologically negative by the Woo test and in the enzyme-linked immunosorbent assay for T. vivax antibody detection (Tv-ELISA-Ab; Group 2 parasitologically negative and positive in the Tv-ELISA-Ab; and in Group 3 cows were parasitologically positive and with positive reactions in the Tv-ELISA-Ab. During 24 months, the cows' dislodgment between the above established groups was monitored by Woo test and Tv-ELISA-Ab exams. The tabanid population was also monitored and the highest number occurred during the rainy season. Although parasitemias were detected only in the first four samplings of the experimental period, the cows could be considered as trypanotolerant, because no clinical signs were observed. Despite the higher T. vivax incidence during the dry season, no disease symptoms were seen. Even though T. vivax epidemiological situation in the herd was characterized as endemic with seasonal variation, the probability of outbreaks was null within the conditions of the study.Surtos de Trypanosoma vivax em bovinos de corte do Pantanal foram responsáveis por relevante impacto econômico, devido a perda de peso, abortos e mortalidade. Um manejo comum é o deslocamento de bovinos do Pantanal baixo para áreas adjacentes desse ecosistema para reprodução e engorda. Por essa razão, foi efetuado um estudo epidemiológico em rebanho de vacas movidas para uma área de transi

  14. Testing geopressured geothermal reservoirs in existing wells. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    This contract called for the acquisition and testing of Wells of Opportunity. Wells of Opportunity are located by screening published information on oil industry activity and through personal contacts with oil operators. This process resulted in recommendation of 21 candidate wells to the DOE for the WOO program. Of the 21 wells recommended, 7 were accepted. Six of these 7 were acquired for testing. Three wells have been tested, and the fourth and fifth will be tested early in 1981. Preliminary test results are briefly described and are shown in a table. The actual testing schedule and the originally proposed schedule matched very closely. Cumulative costs through November 1980 were approximately $6.5 million and compare to an estimate of $8.5 million for the same period. A graphical comparison of actual versus estimated costs is given.

  15. Listing of Army Fuel-Consuming Nonautomotive Ground Support Equipment.

    Science.gov (United States)

    1981-08-01

    W Z(55I(00W(.J...J0((55(5 X55(S NNN. .6uu m xv~ 00d0. . -z 00 0 0a0 e~ W 0 0 1fl 0 40.28 QUf0=Q lS59uuIIIII 4 a a acca N0QgI %q c a It, 4t 0 0 0 - !3...QO c~lCS- VIC X00 woo" )- 00 0*U- OKKKK3S33S300 xwC w A IWZ -I 2 In -m0N~ - P1 - --- - 004M43101 S C t4IMY-40 £I39M 93 ~ ~ KK A .- I, I - - .- I. 0 0

  16. Fabrication and characterization of anisotropic nanofiber scaffolds for advanced drug delivery systems

    Directory of Open Access Journals (Sweden)

    Jalani G

    2014-05-01

    Full Text Available Ghulam Jalani,* Chan Woo Jung,* Jae Sang Lee, Dong Woo Lim Department of Bionano Engineering, College of Engineering Sciences, Hanyang University, Education Research Industry Cluster at Ansan Campus, Ansan, South Korea*These authors contributed equally to this workAbstract: Stimuli-responsive, polymer-based nanostructures with anisotropic compartments are of great interest as advanced materials because they are capable of switching their shape via environmentally-triggered conformational changes, while maintaining discrete compartments. In this study, a new class of stimuli-responsive, anisotropic nanofiber scaffolds with physically and chemically distinct compartments was prepared via electrohydrodynamic cojetting with side-by-side needle geometry. These nanofibers have a thermally responsive, physically-crosslinked compartment, and a chemically-crosslinked compartment at the nanoscale. The thermally responsive compartment is composed of physically crosslinkable poly(N-isopropylacrylamide poly(NIPAM copolymers, and poly(NIPAM-co-stearyl acrylate poly(NIPAM-co-SA, while the thermally-unresponsive compartment is composed of polyethylene glycol dimethacrylates. The two distinct compartments were physically crosslinked by the hydrophobic interaction of the stearyl chains of poly(NIPAM-co-SA or chemically stabilized via ultraviolet irradiation, and were swollen in physiologically relevant buffers due to their hydrophilic polymer networks. Bicompartmental nanofibers with the physically-crosslinked network of the poly(NIPAM-co-SA compartment showed a thermally-triggered shape change due to thermally-induced aggregation of poly(NIPAM-co-SA. Furthermore, when bovine serum albumin and dexamethasone phosphate were separately loaded into each compartment, the bicompartmental nanofibers with anisotropic actuation exhibited decoupled, controlled release profiles of both drugs in response to a temperature. A new class of multicompartmental nanofibers could be

  17. ORNAMENTAL SPECIES USED IN WATER GARDENS FROM SOUTH KOREA

    Directory of Open Access Journals (Sweden)

    PARK SANG KUN

    2009-12-01

    Full Text Available Aquatic plants (hydrophytic plants or hydrophytes are plants that have adapted to live in or on aquatic environments. Because they are living under the water require numerous special adaptations, aquatic plants can only grow in water or permanently saturated soil. Aquatic vascular plants can be ferns or angiosperms (from a variety of families, including monocots and dicots. As opposed to plants types such as mesophytes and xerophytes, hydrophytes do not have a problem in retaining water due to the abundance of water in its environment. This means the plant has less need to regulate transpiration (indeed, the regulation of transpiration would require more energy than the possible benefits incurred.The Korean vascular flora contains 217 families, 1.045 genera, 3.034 species, and 406 infraspecific taxa [CHONG-WOOK PARK, 2007].In Mokp’o region (South Korea, in 1995, was identified hydrophytes species composed by 11 orders, 22 families, 23 genera, 38 species, 9 varieties, total 48 taxa. These were composed by 22 taxa emerged plants, 15 taxa floating-leaves plants, 8 taxa submerged plants and 3 taxa free-floating plants [JEONG WOO-GYU & al., 1995].The same research collective, in 1996, in Paksil, Yundang (South Korea swamp region was identified hydrophytes species composed by 11 orders, 22 families, 31 genera, 41 species, 10 varieties; it represents 12.1% of total plants. These is composed of 25 taxa emerged plants, 15 taxa floating-leaves plants, 9 taxa submerged plants and 3 taxa free-floating plants [JEONG WOO-GYU & al., 1996].This paper contains the classification of water plants and a brief description of some aquatic species used in Korean ancient and modern gardens in order to introduce in our country.

  18. Outcome and risk of revision following shoulder replacement in patients with glenohumeral osteoarthritis.

    Science.gov (United States)

    Rasmussen, Jeppe V

    2014-06-01

    This thesis includes four studies focusing on the functional outcome, shoulder-specific quality of life and risk of revision following shoulder replacement in patients with glenohumeral osteoarthritis without symptomatic rotator cuff pathology. The Danish version of WOOS, translated according to international standardized guidelines, had substantial psychometric properties comparable to the original version. It is recommendable to use WOOS in the evaluation of patients with glenohumeral osteoarthritis treated with shoulder replacement. Data from DSR showed that the shoulder specific quality of life following total shoulder arthroplasty was superior to that of hemiarthroplasty (resurfacing hemiarthroplasty and stemmed hemiarthroplasty). The difference between stemmed hemiarthroplasty and resurfacing hemiarthroplasty was small and did not exceed the minimal clinically important difference. The revision rate following resurfacing hemiarthroplasty was surprisingly high compared with previous reports but there were no statistical significant differences in revision rate between arthroplasty designs. The shoulder specific quality of life and revision rate in patients under the age of 55 was worrying. The use of resurfacing hemiarthroplasty has relied on the results from case series only. The efficacy in the treatment of glenohumeral osteoarthritis has been promising but the CMS found in the randomized clinical trial indicate that the functional outcome may be inferior to that of stemmed hemiarthroplasty and less favourable than previously reported. However, the limited number of patients may have influenced the results and a larger definitive RCT is needed.Shoulder replacement is relevant and effective in the treatment of glenohumeral osteoarthritis; however, resurfacing hemiarthroplasty was associated with a poorer outcome and a higher risk of revision than previously assumed especially in patients under the age of 55. Based on data from this thesis, and based on

  19. Using Multiscale Product for ECG Characterization

    Directory of Open Access Journals (Sweden)

    Rym Besrour

    2009-01-01

    Full Text Available This paper introduces a new method for R wave's locations using the multiscale wavelet analysis, that is based on Mallat's and Hwang's approach for singularity detection via local maxima of the wavelet coefficients signals. Using a first derivative Gaussian function as prototype wavelet, we apply the pointwise product of the wavelet coefficients (PWCs over some successive scales, in order to enhance the peak amplitude of the modulus maxima line and to reduce noise. The R wave corresponds to two modulus maximum lines with opposite signs (min-max of multi-scale product. The proposed algorithm does not include regularity analysis but only amplitude-based criteria. We evaluated the algorithm on two manually annotated databases, such as MIT-BIH Arrhythmia and QT.

  20. 23rd International Workshop in Operator Theory and its Applications

    CERN Document Server

    Dritschel, Michael; Elst, AFM; Portal, Pierre; Potapov, Denis

    2014-01-01

    This book comprises the proceedings of the Mathematical Physics and MathematicsIII International Workshop on Operator Theory and its Applications (IWOTA 2012), which was held at the University of New South Wales (Sydney, Australia) from 16 July to 20 July 2012. It includes twelve articles presenting both surveys of current research in operator theory and original results. The contributors are A. Amenta P. Auscher and S. Stahlhut W. Bauer C. Herrera Yañez and N. Vasilevski C.C. Cowen, S. Jung and E. Ko R.E. Curto, I.S. Hwang and W.Y. Lee S. Dey and K.J. Haria F. Gesztesy and R. Weikard G. Godefroy B. Jefferies S. Patnaik and G. Weiss W.J. Ricker A. Skripka

  1. Demarcating misconduct from misinterpretations and mistakes

    DEFF Research Database (Denmark)

    Andersen, Hanne

    2012-01-01

    Within recent years, scientific misconduct has become an increasingly important topic, not only in the scientific community, but in the general public as well. Spectacular cases have been extensively covered in the news media, such as the cases of the Korean stem cell researcher Hwang, the German...... for dealing with scientific misconduct were introduced in the 1990s. At this time, research agencies, universities and other research institutions around the world developed guidelines for good scientific practice and formed committees to handle cases of scientific misconduct. In this process it was widely...... debated how to define scientific misconduct. Most definitions centered on falsification, fabrication, and plagiarism (the so-called FFP definition), but suggestions were also made for definitions that were broader and more open-ended, such as the 1995 suggestion from the US Commission of Research...

  2. Designing Open Source Computer Models for Physics by Inquiry using Easy Java Simulation

    CERN Document Server

    Wee, Loo Kang

    2012-01-01

    The Open Source Physics community has created hundreds of physics computer models (Wolfgang Christian, Esquembre, & Barbato, 2011; F. K. Hwang & Esquembre, 2003) which are mathematical computation representations of real-life Physics phenomenon. Since the source codes are available and can be modified for redistribution licensed Creative Commons Attribution or other compatible copyrights like GNU General Public License (GPL), educators can customize (Wee & Mak, 2009) these models for more targeted productive (Wee, 2012) activities for their classroom teaching and redistribute them to benefit all humankind. In this interactive event, we will share the basics of using the free authoring toolkit called Easy Java Simulation (W. Christian, Esquembre, & Mason, 2010; Esquembre, 2010) so that participants can modify the open source computer models for their own learning and teaching needs. These computer models has the potential to provide the experience and context, essential for deepening students c...

  3. Improving community ambulation after hip fracture: protocol for a randomised, controlled trial

    Directory of Open Access Journals (Sweden)

    D Orwig

    2017-01-01

    Analysis: Analyses for all aims will be performed according to the intention-to-treat paradigm. Except for testing of the primary hypothesis, all statistical tests will be two-sided and not adjusted for multiple comparisons. The test of the primary hypothesis (comparing groups on the proportion who are community ambulators at 16 weeks after randomisation will be based on a one-sided 0.025-level hypothesis test using a procedure consisting of four interim analyses and one final analysis with critical values chosen by a Hwang-Shih-Decani alpha-spending function. Analyses will be performed to test group differences on other outcome measures and to examine the differential impac

  4. Excited-state quantum phase transition in the Rabi model

    Science.gov (United States)

    Puebla, Ricardo; Hwang, Myung-Joong; Plenio, Martin B.

    2016-08-01

    The Rabi model, a two-level atom coupled to a harmonic oscillator, can undergo a second-order quantum phase transition (QPT) [M.-J. Hwang et al., Phys. Rev. Lett. 115, 180404 (2015), 10.1103/PhysRevLett.115.180404]. Here we show that the Rabi QPT accompanies critical behavior in the higher-energy excited states, i.e., the excited-state QPT (ESQPT). We derive analytic expressions for the semiclassical density of states, which show a logarithmic divergence at a critical energy eigenvalue in the broken symmetry (superradiant) phase. Moreover, we find that the logarithmic singularities in the density of states lead to singularities in the relevant observables in the system such as photon number and atomic polarization. We corroborate our analytical semiclassical prediction of the ESQPT in the Rabi model with its numerically exact quantum mechanical solution.

  5. Open Source Physics

    CERN Document Server

    Wee, Loo Kang

    2013-01-01

    Open Source Physics (Brown, 2012; Christian, 2010; Esquembre, 2012; Hwang, 2010) empowers teachers and students to create and use these free tools with the associated intellectual property rights given to customise (Wee & Mak, 2009) the computer models/tools to suit their teaching and learning needs. Open Source Physics (OSP) focuses on design of computer models, such as Easy Java Simulations (EJS) and the use of video modeling and analysis (Tracker). They allow students to investigate, explore and analyse data which is either real or simulated. The OSP approach helps users overcome barriers in creating, using and scaling up meaningful ICT use in education. In Singapore, teachers and students have created or customised existing computer models to design and re-purpose EJS models to suit their context and learning needs. Tracker tools allow students to analyse different aspects of a physics phenomena to deepen their understanding of abstract physics concepts. Using Tracker, students record the motion of ob...

  6. Discussion, debate and dialog: changing minds about conceptual change research in science education

    Science.gov (United States)

    Dillon, Justin

    2008-07-01

    This paper provides a critical commentary on a suite of eight papers, which focus on conceptual change research in science education. Responses by Mercer, Smardon and Wells to a paper by Treagust and Duit are observed to reflect the backgrounds of the three authors with Wells focusing on issues of ontology and the affective domain. Mercer and Smardon focus on issues of identity and the role of dialog. Hewson's, Vosniadou's and Tiberghien's responses to Roth, Lee and Hwang offer robust critique of what appear to be exploratory ideas. To what extent the authors of the response papers enter into dialog with the papers is discussed. How far research into learning in science has progressed since the 1980s is examined.

  7. Experimental and theoretical strain distributions for stationary and growing cracks

    Science.gov (United States)

    Gerberich, W. W.; Davidson, D. L.; Kaczorowski, M.

    E XPERIMENTAL strain distributions are determined very near the crack tip in Fe-3wt.%Si single crystals. Both in situ stereoimaging and electron channeling techniques give reasonably reproducible distributions. By growing fatigue cracks on a {100} cleavage plane, the singularity strengths have been determined for both growing and stationary cracks under relatively plane stress and plane strain conditions. This has allowed a comparison to existing theoretical models. It is shown that the HRR singularity (Hutchinson, Rice and Rosengren, 1968) for stationary cracks is very good to within I μm of the crack tip and a hardening model for the growing crack (gao and hwang, Advances in Fracture Research, edited by D. Francois. 5th Int. Conf. on Fracture, Cannes, France, 2, 669, 1981) is surprisingly good. Other issues such as fracture criteria are discussed since strains greater than unity were measured at the crack tip in this relatively brittle material.

  8. 一种高效的防欺诈在线秘密分享方案%Efficient On-line Secret Sharing Scheme to Identify Cheaters

    Institute of Scientific and Technical Information of China (English)

    赵建杰; 张建中

    2007-01-01

    基于离散对数难解性及Hwang-Chang方案提出了一种新的在线秘密分享方案.在该方案中,秘密分享的参与者自己选择秘密份额,使得秘密分发者和各参与者之间不需要维护安全信道;每个参与者可以在秘密恢复阶段验证其他参与者是否进行了欺诈而不需要构造专门的验证函数;每个参与者只需维护一个秘密份额就可以实现多秘密的分享.

  9. A new methodology for water resources multicriteria decision making under uncertainty

    Science.gov (United States)

    Simonovic, Slobodan P.; Verma, Rakesh

    A multiciteria decision making problem in water resource is addressed through the generation of fuzzy Pareto optimal set. Methodology is using positive and negative ideal solutions (Lai, Y.-J., Liu, T.-Y., Hwang, C.L. (1994). TOPSIS for MODM. European Journal of Operational Research 76, 486-500) and a set of weights assigned to the objective functions in fuzzy triangular form. Solution of the problem is obtained by transforming each objective function into a set of three objective functions. A planning problem of multicriteria waste water treatment from the literature is used as an illustrative example to demonstrate the utility of the proposed methodology. The obtained fuzzy Pareto solution set has been compared with the deterministic solution set. It is shown that the proposed approach can: (a) capture the uncertainty associated with the assignment of weights; and (b) provide the decision makers with a wider range of solutions to select from.

  10. VizieR Online Data Catalog: PACS Evolutionary Probe (PEP-DR1) catalogs (Lutz+, 2011)

    Science.gov (United States)

    Lutz, D.; Poglitsch, A.; Altieri, B.; Andreani, P.; Aussel, H.; Berta, S.; Bongiovanni, A.; Brisbin, D.; Cava, A.; Cepa, J.; Cimatti, A.; Daddi, E.; Dominguez-Sanchez, H.; Elbaz, D.; Foerster Schreiber, N. M.; Genzel, R.; Grazian, A.; Gruppioni, C.; Harwit, M.; Le Floc'h, E.; Magdis, G.; Magnelli, B.; Maiolino, R.; Nordon, R.; Perez Garcia, A. M.; Popesso, P.; Pozzi, F.; Riguccini, L.; Rodighiero, G.; Saintonge, A.; Sanchez Portal, M.; Santini, P.; Shao, L.; Sturm, E.; Tacconi, L. J.; Valtchanov, I.; Wetzstein, M.; Wieprecht, E.

    2013-11-01

    PACS catalogs built by the PEP team, with key contributions by Stefano Berta, Benjamin Magnelli, Paola Popesso, Dieter Lutz, Francesca Pozzi, Bruno Altieri, Herve Aussel, Hoseong Hwang, Emeric Le Floc'h, Georgios Magdis, Raanan Nordon, Albrecht Poglitsch, Laurie Riguccini, Amelie Saintonge, Li Shao. For more details, please refer to Lutz et al. (2011A&A...532A..90L) and to the PDF documentation associated to the release. Data and catalogs can be retrieved from the web page http://www.mpe.mpg.de/ir/Research/PEP/publicdatareleases.php See the PDF documentation associated to the PEP DR1 release, http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_global.pdf and http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_SPIRE.pdf for more details. (69 data files).

  11. Remote sensing of hydrological connectivity

    Science.gov (United States)

    Schultz, Colin

    2012-08-01

    The sub-surface flow of water within a watershed is traditionally thought to depend solely on topographic or physical influences, such as slope, soil permeability, and channel density. Though often overlooked, some researchers propose that the role of vegetation and its feedback on subsurface flow could be just as important in some cases. Plants tend to increase subsurface flow by increasing soil conductivity and preferential flow paths. They can also cause it to decline, as plants use subsurface water and nutrients to fuel their growth, drawing it out of the system through evapotranspiration. Both sets of feedbacks affect the downslope availability of water. To capitalize on this idea, Hwang et al. devised a system called the hydrological vegetation gradient (HVG).

  12. The onion-ring structure for Pd-Pt bimetallic clusters.

    Science.gov (United States)

    Cheng, Daojian; Wang, Wenchuan; Huang, Shiping

    2006-08-24

    The onion-ring structure is validated in the Pd-Pt bimetallic clusters of total atom numbers 147 and 309 through the Monte Carlo method by using the second-moment approximation of the tight-binding (TB-SMA) potentials, which is conceived in predicting the possible structures of the bimetallic clusters by He et al. [J. Am. Chem. Soc. 2003, 125, 11034] and Hwang et al. [J. Am. Chem. Soc. 2005, 127, 11140]. In the onion-ring structure, Pd atoms and Pt atoms occupy alternate layers of the clusters. The formation of the onion-ring structure can be associated with the fact that the single Pt impurity is favorable to stay in the subsurface layer and the central part of bimetallic clusters.

  13. Foliation theory in algebraic geometry

    CERN Document Server

    McKernan, James; Pereira, Jorge

    2016-01-01

    Featuring a blend of original research papers and comprehensive surveys from an international team of leading researchers in the thriving fields of foliation theory, holomorphic foliations, and birational geometry, this book presents the proceedings of the conference "Foliation Theory in Algebraic Geometry," hosted by the Simons Foundation in New York City in September 2013.  Topics covered include: Fano and del Pezzo foliations; the cone theorem and rank one foliations; the structure of symmetric differentials on a smooth complex surface and a local structure theorem for closed symmetric differentials of rank two; an overview of lifting symmetric differentials from varieties with canonical singularities and the applications to the classification of AT bundles on singular varieties; an overview of the powerful theory of the variety of minimal rational tangents introduced by Hwang and Mok; recent examples of varieties which are hyperbolic and yet the Green-Griffiths locus is the whole of X; and a classificati...

  14. A Cryptosystem for Encryption and Decryption of Long Confidential Messages

    Science.gov (United States)

    Giri, Debasis; Barua, Prithayan; Srivastava, P. D.; Jana, Biswapati

    In this paper, we propose a cryptosystem which can encrypt and decrypt long (text) messages in efficient manner. The proposed cryptosystem is a combination of symmetric-key and asymmetric-key cryptography, where asymmetric-key cryptography is used to transmit the secret key to an intended receiver and the sender/receiver encrypts/decrypts messages using that secret key. In 2002, Hwang et al. proposed a scheme for encrypting long messages. The main drawback of their scheme is that it requires more computational overhead. Our proposed scheme is more efficient from the computational point of view compared to that of their scheme. Our scheme is a block cipher, long messages are broken into fixed length plaintext blocks for encryption. It supports parallel computation, since encryption/decryption of all the blocks of plaintext/plaintext are independent and thus can be carried out simultaneously. In addition, our scheme retains the same security level as their scheme.

  15. Update on bariatric surgical procedures and an introduction to the implantable weight loss device: the Maestro Rechargeable System

    Directory of Open Access Journals (Sweden)

    Hwang SS

    2016-08-01

    Full Text Available Stephanie S Hwang,1 Mark C Takata,1 Ken Fujioka,2 William Fuller1 1Division of General/Bariatric Surgery, Scripps Clinic Weight Management, 2Division of Diabetes and Endocrinology, Scripps Clinic, La Jolla, CA, USA Abstract: There are many different methods of treating obesity, ranging from various medical options to several surgical therapies. This paper briefly summarizes current surgical options for weight loss with a focus on one of the newest US Food and Drug Administration-approved devices for surgical weight loss therapy, the Maestro Rechargeable System. Also known as the vagal blocking for obesity control implantable device, this tool blocks vagal nerve activity to induce weight loss. Keywords: VBLOC device, vagal, vagus, obesity

  16. X-Integrationism for Chinese Indigenous Management Research

    DEFF Research Database (Denmark)

    Li, Xin

    2015-01-01

    Regarding philosophical foundation of Chinese indigenous management research, Prof. Kwang Kuo Hwang of Taiwan University and Prof. Peter P. Li of Copenhagen Business School have contradictory judgments. Their opinions represent two opposite poles. This paper tries to offer a middle route between...... these two poles. The author does not fully agree with Hwang’s argument that Chinese indigenous management research must adopt Western philosophies of science, nor does he agree with Li’s philosophy of wisdom interpretation of Chinese traditional philosophy. By integrating multiple philosophical elements...... rooted in China and the West, such as, Chinese Yin Yang thinking, Daoism, Confucianism, Bohr’s complementarity principle, and Hegel’s dialectic logic, this paper tries to construct the daoliology, epistemology and methodology of Chinese indigenous management research....

  17. Attack on the Enhanced Multiparty Quantum Secret Sharing

    Institute of Scientific and Technical Information of China (English)

    杨帅; 陈秀波; 杨义先

    2012-01-01

    Recently, Gao et al.'s [Commun. Theor. Phys. 52 (2009) 421] multiparty quantum secret sharing (MQSS) protocol with two-photon three-dimensional Bell states was enhanced by Hwang et al. [Commun. Theor. Phys. 56 (2011) 79]. The improved protocol removes some unnecessary unitary operations, devices, and transmissions by the technique of decoy single photons and careful modification. However, in this paper, we investigate the security of the improved protocol and find it is insecure. The eavesdropper can steal all Alice's secret information. Furthermore, a feasible modification to remedy the security loophole is put forward. Our improved protocol provides a basic method to modify a kind of MQSS protocols which cannot resist the collusion attack.

  18. ON THE UPPER GENERALIZED EXPONENTS OF MINISTRONG DIGRAPHS

    Institute of Scientific and Technical Information of China (English)

    周波

    2001-01-01

    @@ 1. Introduction A digraph G is called primitive if there exists a positive integer k such that there is a walk of length k from u to v for each ordered pair of not necessarily distinct vertices u and v. The smallest such k is called the exponent of G, denoted by γ(G). Exponents for primitive digraphs have been studied extensively due to their intrinsic importance in graph theory, combinatorics, matrix theory, and their applications in communication problems. As a generalization of exponents, Brualdi and Liu[1] introduced the concept of upper generalized exponents for primitive digraphs. Recently, Shao, Wu and Hwang[2'3] extended this concept of upper generalized exponents from primitive digraphs to general digraphs which are not necessarily primitive.

  19. Theoretical foundation of Chinese medicine: a modern interpretation.

    Science.gov (United States)

    Wei, L Y

    The theoretical foundation of Chinese medicine as laid down in Hwang Ti Nei Ching is presented and interpreted here in modern language and conception. Our attempt is to bring Chinese medicine in harmony with Western science. Three Yin-Yang laws are formulated based on I Ching and Nei Ching and are justified from physics, mathematics and biology. The Wu-Hsing dynamic model is explained on the basis of dynamic interactions rather than static elements. The Ching-Lo doctrine is stressed upon its apparent correlations with the autonomic nervous system. Finally, the Chi is taken to play a role in life as the fields (gravitational, magnetic, nuclear, etc.) do in the physical world.

  20. Note on a paradox in decision-theoretic interval estimation

    CERN Document Server

    Kabaila, Paul

    2012-01-01

    Confidence intervals are assessed according to two criteria, namely expected length and coverage probability. In an attempt to apply the decision-theoretic method to finding a good confidence interval, a loss function that is a linear combination of the interval length and the indicator function that the interval includes the parameter of interest has been proposed. We consider the particular case that the parameter of interest is the normal mean, when the variance is unknown. Casella, Hwang and Robert, Statistica Sinica, 1993, have shown that this loss function, combined with the standard noninformative prior, leads to a generalized Bayes rule that is a confidence interval for this parameter which has "paradoxical behaviour". We show that a simple modification of this loss function, combined with the same prior, leads to a generalized Bayes rule that is the usual confidence interval i.e. the "paradoxical behaviour" is removed.

  1. A incrível história da fraude dos embriões clonados e o que ela nos diz sobre ciência, tecnologia e mídia The amazing story of the fraudulent cloned embryos and what it tells us about science, technology, and the media

    Directory of Open Access Journals (Sweden)

    Iara Maria de Almeida Souza

    2010-06-01

    Full Text Available Analisa, a partir de notícias em jornais brasileiros, o caso da fraude científica dos embriões clonados, cometida pelo cientista sul-coreano Hwang. A exposição da ciência pela mídia costuma destacar aspectos intelectuais, descobertas e promessas de aplicação. Nesse caso a ciência é mostrada em seu avesso, e desvela-se a trama de fios que ligam elementos de naturezas diferentes: governo coreano, pesquisadores, instrumentos, fundos para pesquisa, óvulos e fungos, revistas científicas, entre outros. Tais vínculos, que constituem a ciência na prática, só ganham visibilidade na mídia devido às tensões entre esses diferentes elementos e aos aspectos ilícitos presentes nesse caso em particular.Based on news reports from Brazilian papers, the article examines the case of scientific fraud involving cloned embryos, committed by South Korean scientist Hwang. The media generally focus on the intellectual process of science, its discoveries, and the new possibilities it promises. In this case, however, science is shown the other way around, revealing a web that interweaves elements of a radically disparate nature, like the Korean government, researchers, tools, research funds, human eggs and funguses, scientific journals, among others. These ties are what make up science in practice, yet they only become visible in the media when there is tension between them and, in this case, when something illicit happens.

  2. Low-cost flexible supercapacitors with high-energy density based on nanostructured MnO2 and Fe2O3 thin films directly fabricated onto stainless steel

    Science.gov (United States)

    Gund, Girish S.; Dubal, Deepak P.; Chodankar, Nilesh R.; Cho, Jun Y.; Gomez-Romero, Pedro; Park, Chan; Lokhande, Chandrakant D.

    2015-07-01

    The facile and economical electrochemical and successive ionic layer adsorption and reaction (SILAR) methods have been employed in order to prepare manganese oxide (MnO2) and iron oxide (Fe2O3) thin films, respectively with the fine optimized nanostructures on highly flexible stainless steel sheet. The symmetric and asymmetric flexible-solid-state supercapacitors (FSS-SCs) of nanostructured (nanosheets for MnO2 and nanoparticles for Fe2O3) electrodes with Na2SO4/Carboxymethyl cellulose (CMC) gel as a separator and electrolyte were assembled. MnO2 as positive and negative electrodes were used to fabricate symmetric SC, while the asymmetric SC was assembled by employing MnO2 as positive and Fe2O3 as negative electrode. Furthermore, the electrochemical features of symmetric and asymmetric SCs are systematically investigated. The results verify that the fabricated symmetric and asymmetric FSS-SCs present excellent reversibility (within the voltage window of 0-1 V and 0-2 V, respectively) and good cycling stability (83 and 91%, respectively for 3000 of CV cycles). Additionally, the asymmetric SC shows maximum specific capacitance of 92 Fg-1, about 2-fold of higher energy density (41.8 Wh kg-1) than symmetric SC and excellent mechanical flexibility. Furthermore, the “real-life” demonstration of fabricated SCs to the panel of SUK confirms that asymmetric SC has 2-fold higher energy density compare to symmetric SC.

  3. 红花尔基自然保护区天然樟子松林种内种间竞争分析%Analyses of intraspecific and interspecific competition of Pinus sylvestris var. mongolica natural forest in Honghuaerji Nature Reserve of Inner Mongolia

    Institute of Scientific and Technical Information of China (English)

    毛磊; 杨丹青; 王冬梅; 杨晓晖

    2008-01-01

    运用Hegyi单木竞争指数分析了内蒙古红花尔基自然保护区天然樟子松(Pinus sylvestris var.mongolicaLitv.)林内所有胸径大于2 cm的樟子松、山杨(Populus davidiana Dode.)、白桦(Betula platyphylla Suk.)和山荆子(Malus baccata L.)的种内和种间竞争强度.结果表明,样地中主要的竞争木和对象木均为樟子松和白桦;樟子松的种内竞争强度(0.534)远大于种间竞争强度.随径级的增大,樟子松的种内竞争强度逐渐减小,且与胸径存在幂函数关系CI=A·D-B.胸径达到30 cm后,樟子松种内竞争强度变化不明显.作为竞争木,樟子松对其他树种产生了较大的竞争压力.

  4. The post 9/11 period in American literature: from fear and estrangement to interest and dialogue. Rugsėjo vienuoliktosios pasekmės amerikiečių literatūrai: nuo baimės ir susvetinėjimo iki susidomėjimo ir dialogo

    Directory of Open Access Journals (Sweden)

    Ingrida Žindžiuvienė

    2008-01-01

    Full Text Available Straipsnyje apžvelgiama tragiško įvykio JAV istorijoje (2001 m. rugsėjo vienuoliktosios įtaka amerikiečių literatūrai. Ši tragedija šalyje sukėlė ilgalaikį potrauminį efektą, paskatinusį amerikiečių rašytojus rinktis terorizmo apraiškų temas. Vienas jų, John Updike (g. 1932, priskiriamas prie amerikiečių rašytojų, analizuojančių individo būklę, moralinių vertybių paieškas. Savo romanuose John Updike aprašo šiuolaikinio gyvenimo ypatumus, psichologines traumas, žmonijos žiaurumą, brutalumą ir nesuvokiamą blogį. 2006 m. parašytame romane Terrorist („Teroristas“ rašytojas pateikia šiuolaikinės amerikiečių visuomenės, kurioje vyrauja baimė ir įtampa, analizę. Aprašydamas jauno teroristo gyvenimą, rašytojas pabrėžia amerikietiškos visuomenės ydas ir analizuoja šalies politinę situaciją.

  5. A one-loop test for construction of 4D N=4 SYM from 2D SYM via fuzzy sphere geometry

    CERN Document Server

    Matsuura, So

    2015-01-01

    As a perturbative check of the construction of four-dimensional (4D) ${\\cal N}=4$ supersymmetric Yang-Mills theory (SYM) from mass deformed ${\\cal N}=(8,8)$ SYM on the two-dimensional (2D) lattice, the one-loop effective action for scalar kinetic terms is computed in ${\\cal N}=4$ $U(k)$ SYM on ${\\mathbb R}^2 \\times$ (fuzzy $S^2$), which is obtained by expanding 2D ${\\cal N}=(8,8)$ $U(N)$ SYM with mass deformation around its fuzzy sphere classical solution. The radius of the fuzzy sphere is proportional to the inverse of the mass. We consider the two successive limits; (1) decompactify the fuzzy sphere to a noncommutative (Moyal) plane and (2) turn off the noncommutativity of the Moyal plane. It is clear at the classical level to obtain the ordinary ${\\cal N}=4$ SYM on ${\\mathbb R}^4$ in the limits, while it is nontrivial at the quantum level. The one-loop effective action for $SU(k)$ sector of the gauge group $U(k)$ coincides with that of the ordinary 4D ${\\cal N}=4$ SYM in the above limits. Although "noncomm...

  6. Славянофильский подтекст романа А. Платонова Чевенгур | Slavianofiliškos A. Platonovo romano “Čevenguras” potekstės

    Directory of Open Access Journals (Sweden)

    Александр Дырдин

    2006-01-01

    Full Text Available Straipsnyje nagrinėjamas filosofinis A. Platonovo romanas „Čevenguras“ ir analizuojama šio rašytojo kaip slavianofilų įpėdinio pozicija, kadangi slavianofiliškos pažiūros romane pateikiamos įvairiuose kontekstuose, kurių loginė jungtis skirtinga. Kaip ir slavianofilai, A. Platonovas siekia atskleisti objektyvią pasaulio esmę, apjungdamas prigimtį ir dvasingumą. Rašytojo pasaulėjauta susisiekia su slavianofiliškomis pažiūromis jo pastangoje išskirti rusišką liaudiško tiesos ieškotojo tipą, akumuliavusį savyje tikėjimą „kaip proto galią“ (A. Chomiakovas. Romane „Čevenguras“ A. Platonovas pavaizdavo įvairias nacionalinio charakterio apraiškas ir sukūrė apibendrintą ruso stačiatikio paveikslą. Straipsnio autorius daro prielaidą, kad unikalios dvasinės rusų liaudies ir kultūros misijos idėjos samprata galima apibūdinti, nors ir ne visai išsamiai, kūrybinę A. Platonovo filosofiją.

  7. Major changes and improvements of dialysis therapy in Korea: review of end-stage renal disease registry.

    Science.gov (United States)

    Jin, Dong Chan

    2015-01-01

    The Korean Society of Nephrology (KSN) launched a nationwide end-stage renal disease (ESRD) patient registry in 1985 called the Insan Prof. Byung-Suk Min Memorial ESRD Patient Registry. KSN members voluntarily participate in this registry, which has been collecting data through the Internet since 2000. The KSN ESRD patient registry data were reviewed to elucidate the major changes and improvements in dialysis therapy in Korea. The data review revealed: a rapid increase in the number of patients with ESRD; an increase in the number of patients with diabetic nephropathy; a decrease in the proportion of patients undergoing peritoneal dialysis; an increase in the role of private dialysis clinics; an increase in the number of elderly patients undergoing dialysis and the number of patients undergoing long-term dialysis; a decrease in mean blood pressure and an increase in pulse pressure; improvement in anemia treatment; improvement in dialysis adequacy; and improvement in the survival of patients undergoing dialysis. In conclusion, improvements have been made in blood pressure control, anemia treatment, and dialysis adequacy despite increases in the number of elderly patients, diabetic patients, and patients on long-term dialysis during the last two decades in Korea.

  8. Gold nanoparticle–choline complexes can block nicotinic acetylcholine receptors

    Directory of Open Access Journals (Sweden)

    Chur Chin

    2010-04-01

    Full Text Available Chur Chin1, In Kyeom Kim2, Dong Yoon Lim3, Ki Suk Kim4, Hyang Ae Lee4, Eun Joo Kim41Department of Pediatrics, Fatima Hospital, Daegu, Korea; 2Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu, Korea; 3Department of Pharmacology, School of Medicine, Chosun University, Gwangju, Korea; 4Korea Institute of Toxicology, Daejeon, KoreaAbstract: We identified a novel class of direct ion-channel blockers of ligand-gated ion channels called the gold nanoparticle–choline complex. Negatively charged gold nanoparticles (1.4 nm block ion pores by binding to the sulfur group of the cysteine loop of nicotinic acetylcholine receptors (nAChRs, and currents evoked by acetylcholine (Ach can break these bonds. The current evoked by ACh in nAChRs was blocked directly in ion pores by the gold nanoparticle–choline complex. In adrenal-gland perfusion studies, the complex also blocked nAChRs by diminishing catecholamine release by about 75%. An in vivo study showed muscle relaxation in rats after injection of the complex. These results will foster the application of gold nanoparticles as a direct ion-channel blocker. Keywords: negatively charged gold nanoparticle, choline, gold–sulfur bond, nicotinic acetylcholine receptor, direct ion-channel blocker

  9. The effect of fire disturbance on short-term soil respiration in typical forest of Greater Xing’an Range, China

    Institute of Scientific and Technical Information of China (English)

    Long Sun; Tongxin Hu; Ji Hong Kim; Futao Guo; Hong Song; Xinshuang Lv; Haiqing Hu

    2014-01-01

    We investigated the effect of fire disturbance on short-term soil respiration in birch (Betula platyphylla Suk.) and larch (Larix gmelinii Rupr.) forests in Greater Xing’an range, northeastern China for further understanding of its effect on the carbon cycle in ecosystems. Our study show that post-fire soil respiration rates in B. platyphylla and L. gmelinii forests were reduced by 14%and 10%, respectively. In contrast, the soil heterotrophic respiration rates in the two types of forest were similar in post-fire and control plots. After fire, the contribution of root respiration to total soil respiration was dramatically reduced. Variation in soil respiration rates was explained by soil moisture (W) and soil tem-perature (T) at a depth of 5 cm. Exponential regression fitted T and W models explained Rs rates in B. platyphylla control and post-fire plots (83.1% and 86.2%) and L. gmelinii control and post-fire plots (83.7%and 88.7%). In addition, the short-term temperature coefficients in B.

  10. Fredkin Spin Chain

    CERN Document Server

    Salberger, Olof

    2016-01-01

    We introduce a new model of interacting spin 1/2. It describes interaction of three nearest neighbors. The Hamiltonian can be expressed in terms of Fredkin gates. The Fredkin gate (also known as the CSWAP gate) is a computational circuit suitable for reversible computing. Our construction generalizes the work of Ramis Movassagh and Peter Shor. Our model can be solved by means of Catalan combinatorics in the form of random walks on the upper half of a square lattice [Dyck walks]. Each Dyck path can be mapped to a wave function of the spins. The ground state is an equally weighted superposition of Dyck walks [instead of Motzkin walks]. We can also express it as a matrix product state. We further construct the model of interacting spins 3/2 and greater half-integer spins. The models with higher spins require coloring of Dyck walks. We construct SU(k) symmetric model [here k is the number of colors]. The leading term of the entanglement entropy is then proportional to the square root of the length of the lattice ...

  11. Новая искренность советской поэтессы: «Последние стихи» Елены Ширман | Sovietinės poetės naujasis nuoširdumas: Jelenos Širman „Paskutinės eilės“

    Directory of Open Access Journals (Sweden)

    Таисия Лаукконен

    2010-01-01

    Full Text Available 1941 metais sovietinė poetė Jelena Širman (1908–1942 sukūrė neįprasto likimo eilėraštį „Paskutinės eilės“. Širman dienoraštį, kuriame jis buvo užrašytas, žuvus šeimininkei išsaugojo vienas iš jos nužudymo liudytojų. Pirmą sykį eilėraštis publikuotas atlydžio laikais. III tūkstantmečio pradžioje eilėraštį „atrado“ filologas ir poetas Danila Davydovas, perspausdino ir aptarė naujojo nuoširdumo poezijos kontekste. Po kiek laiko eilėraštis sparčiai paplito internete ir susilaukė tiek „nesuinteresuotų“ skaitytojų, tiek literatūros veikėjų dėmesio. Straipsnyje aptariami eilėraščio kūrimo, publikacijos ir republikacijos kontekstai, siekiant pademonstruoti, kaip keitėsi jo suvokimas bei kokias reikšmes jam primeta naujojo nuoširdumo kontekstas.

  12. Interpolating the Coulomb Phase of Little String Theory

    CERN Document Server

    Lin, Ying-Hsuan; Wang, Yifan; Yin, Xi

    2015-01-01

    We study up to 8-derivative terms in the Coulomb branch effective action of (1,1) little string theory, by collecting results of 4-gluon scattering amplitudes from both perturbative 6D super-Yang-Mills theory up to 4-loop order, and tree-level double scaled little string theory (DSLST). In previous work we have matched the 6-derivative term from the 6D gauge theory to DSLST, indicating that this term is protected on the entire Coulomb branch. The 8-derivative term, on the other hand, is unprotected. In this paper we compute the 8-derivative term by interpolating from the two limits, near the origin and near the infinity on the Coulomb branch, numerically from SU(k) SYM and DSLST respectively, for k=2,3,4,5. We discuss the implication of this result on the UV completion of 6D SYM as well as the strong coupling completion of DSLST. We also comment on analogous interpolating functions in the Coulomb phase of circle-compactified (2,0) little string theory.

  13. A Novel R2R3-MYB Transcription Factor BpMYB106 of Birch (Betula platyphylla) Confers Increased Photosynthesis and Growth Rate through Up-regulating Photosynthetic Gene Expression.

    Science.gov (United States)

    Zhou, Chenguang; Li, Chenghao

    2016-01-01

    We isolated a R2R3-MYB transcription factor BpMYB106, which regulates photosynthesis in birch (Betula platyphylla Suk.). BpMYB106 mainly expresses in the leaf and shoot tip of birch, and its protein is localized in the nucleus. We further fused isolated a 1588 bp promoter of BpMYB106 and analyzed it by PLACE, which showed some cis-acting elements related to photosynthesis. BpMYB106 promoter β-glucuronidase (GUS) reporter fusion studies gene, the result, showed the GUS reporter gene in transgenic birch with BpMYB106 promoter showed strong activities in shoot tip, cotyledon margins, and mature leaf trichomes. The overexpression of BpMYB106 in birch resulted in significantly increased trichome density, net photosynthetic rate, and growth rate as compared with the wild-type birch. RNA-Seq profiling revealed the upregulation of several photosynthesis-related genes in the photosynthesis and oxidative phosphorylation pathways in the leaves of transgenic plants. Yeast one-hybrid analysis, coupled with transient assay in tobacco, revealed that BpMYB106 binds a MYB binding site MYB2 in differentially expressed gene promoters. Thus, BpMYB106 may directly activate the expression of a range of photosynthesis related genes through interacting with the MYB2 element in their promoters. Our study demonstrating the overexpression of BpMYB106-a R2R3-MYB transcription factor-upregulates the genes of the photosynthesis and oxidative phosphorylation pathways to improve photosynthesis.

  14. Study on the Relationship between Forest Fire and Forest Types in Saihanba Forest Center%塞罕坝机械林场森林类型与林火关系的研究

    Institute of Scientific and Technical Information of China (English)

    于士涛

    2014-01-01

    该文通过对塞罕坝机械林场野外调查获取实地数据来分析林场的林型特征与火灾的关系,得出结论如下:樟子松纯林属于极易燃类型;白桦林属于中等易燃类型;蒙古栎林属较易燃类型;落叶松和白桦的混交林内属于较难燃类型;落叶松、樟子松和云杉的混交林内属于较易燃类型。%In this dissertation datum gotten by some field investigation was also used to analyze the rela⁃tion between forest fire and the character of forest. The main conclusions as follows:Forest of L. gmelinii is difficult to burn;forest of Pinus sylvestris var. mongolica Litv is very inflammable;forest of Betula platy⁃phylla Suk is mid-inflammable;forest of Quercus mongolica Fisch is correspondingly inflammable. Mixed for⁃est of L. gmelinii and P. sylvestris var. mongolica Litv is uninflammable;mixed forest of L. gmelinii,P. syl⁃vestris var. mongolica Litv and Picea asperata Mast is correspondingly inflammable.

  15. Whiteness and the Blackening of Italy: La guerra cafona, Extracommunitari and Provisional Street Justice

    Directory of Open Access Journals (Sweden)

    Joseph Pugliese

    2008-12-01

    Full Text Available In this essay, I briefly revisit the historical moment of Italian unification, drawing attention to its violent colonial dimensions and the twenty years of insurgent southern brigandage that erupted immediately after unification, in order to begin to trace the survival of this southern insurrectionary and anti-nationalist movement in the contemporary Italian context. In the process of focusing on the manner in which a statue of the Italian national poet, Dante, has been graffitied by southern youth in a square in Naples, I transpose the historical tradition of southern brigandage, returning the term back to its insurgent political roots, in order to begin to establish lines of connection between seemingly disparate politico-cultural practices and genealogies; in particular, I examine contemporary southern hip hop culture, including graffiti and rap, in relation to the history of southern anti-unification and counter-nationalist movements, marking the transmediterranean-atlantic politico-cultural flows that inscribe southern hip hop culture. I conclude by bringing into contemporary focus this northern history of anti-southern discrimination and exploitation by drawing attention to the plight of recent immigrants from the Global South that constitute the underbelly of contemporary Italy’s economic prosperity. My focus here is on mapping points of polico-cultural connection between immigrants of the Global South and meridionali through the instantiation of such tactical cultural practices as establishing suks and transitory markets in Italy’s civic squares.

  16. Accessibility analysis in manufacturing processes using visibility cones

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    [1]Lozana-Prez,T.,Spatial planning: A configuration space approach,IEEE Transactions on Computers,1983,C-32(2): 108-120.[2]Chen,L L,Woo,T C.,Separating and intersecting spherical polygons: Computing machinability on three-,four-,and five-axis numerically controlled machines,ACM Transaction on Graphics,1993,12(4): 305-326.[3]Kweon,S.,Medeiros,D.J.,Part orientations for CMM inspection using dimensioned visibility maps,Computer-Aided Design,1998,30(9): 741-749.[4]Lim,C.P.,Menq,C.H.,CMM feature accessibility and path generation,International Journal of Production Research,1994,32(3): 597-618.[5]Chen,L.L.,Chou,S.Y.,Woo,T.C.,Parting directions for mould and die design,Computer-Aided Design,1993,25(12): 762-768.[6]Yin,Z.P.,Ding,H.,Xiong,Y.L.,Mouldability analysis for near-net-shape manufactured parts using freedom cones,International Journal of Advanced Manufacturing Technology,2000,16(3): 169-175.[7]Wilson,R.H.,On geometric assembly planning,Ph.D.Thesis,Stanford: Stanford University,1992.[8]Spyridl,A.J.,Automatic generation of high level inspection plans for coordinate measuring machines,PhD.Thesis,Los Angeles: University of Southern California,1994.[9]Woo,T.C.,Visibility maps and spherical algorithms,Computer Aided Design,1994,26(1): 6-16.[10]Xiong,Y.L.,Theory of point contacts restraint and qualitative analysis of robot grasping,Science in China,Series A,1994,37(5),629-640.[11]Ding,H.,Xiong,Y.L.,Computational manufacturing,In Intl.Conf.on Frontiers of Design and Manufacturing,2000.[12]Yin,Z.P.,Feature-based product modeling and accessibility analysis for virtual prototyping,Ph.D.Thesis,Wuhan: Huazhong University of Science and Technology,2000.[13]Zhang,H.S.,Effective Occlusion Culling for the Interactive Display of Arbitrary Models,Ph.D.Thesis,Asheville: University of North Carolina,1998.[14]Yin,Z.P.,Ding,H.,Xiong,Y.L.,Visibility theory and algorithms with application to manufacturing processes

  17. Recommendations for SZ/TSPA Model Uncertainty Analysis Concerning the Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    Bogen, K T

    2003-11-05

    This report considers the problem of how best to evaluate the stability (i.e., sampling reliability) of Monte Carlo outputs obtained for two Yucca Mountain Project (YMP) modeling components, namely, outputs for the Saturated Zone (SZ) model, and for the Total System Performance Assessment (TSPA) model. One approach considered is the one that has been employed to date, namely, the application of Monte Carlo methods. Also considered in this context are potential improvements that might be obtained by the additional use of a Monte Carlo ''quitting rule'', such as that defined by Woo (1991), to select the number of Monte Carlo sample runs to perform. By the Monte Carlo approach, each output-value sample (realization) is calculated as a function of a sample-value vector of stochastic realizations, each of which in turn corresponds to a value of a corresponding distributed input variable. Abstractions from the SZ model and the Biosphere model are both used as input to the TSPA model. Sets of stochastic realizations required for SZ and TSPA abstractions ''expensive'' to generate, so the practical issue addressed by a ''quitting rule'' is how to determine what number of realizations is ''enough'' for the purpose of characterizing sampling error in the Monte Carlo estimate obtained for a specified model output of concern. In the TSPA context, the model output of concern is generally considered the time evolution of the arithmetic mean value, an estimator of the expected value, of TSPA-generated annual dose D(t) to the defined receptor within 10,000 y after waste-repository closure. Recommendations below specifically address: (1) whether or not a Monte Carlo approach (such as one employing the Woo quitting rule) is an appropriate basis for undertaking SZ- or TSPA-related uncertainty analysis, and (2) what other method might be more appropriate. While the following discussion and recommendations

  18. Exposure–outcome analysis in depressed patients treated with paroxetine using population pharmacokinetics

    Directory of Open Access Journals (Sweden)

    Kim JR

    2015-09-01

    Full Text Available Jung-Ryul Kim,1 Hye In Woo,2 Mi-Ryung Chun,3 Shinn-Won Lim,4 Hae Deun Kim,5 Han Sung Na,5 Myeon Woo Chung,5 Woojae Myung,6 Soo-Youn Lee,1,3 Doh Kwan Kim6 1Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Seoul, 2Department of Laboratory Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, 3Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 4Samsung Advanced Institute for Health Sciences and Technology (SAIHST, Sungkyunkwan University, Seoul, 5Clinical Research Division, Toxicological Evaluation and Research Department, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Chungcheongbuk-do, 6Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea Purpose: This study investigated population pharmacokinetics of paroxetine, and then performed an integrated analysis of exposure and clinical outcome using population pharmacokinetic parameter estimates in depressed patients treated with paroxetine. Patients and methods: A total of 271 therapeutic drug monitoring (TDM data were retrospectively collected from 127 psychiatric outpatients. A population nonlinear mixed-effects modeling approach was used to describe serum concentrations of paroxetine. For 83 patients with major depressive disorder, the treatment response rate and the incidence of adverse drug reaction (ADR were characterized by logistic regression using daily dose or area under the concentration–time curve (AUC estimated from the final model as a potential exposure predictor. Results: One compartment model was developed. The apparent clearance of paroxetine was affected by age as well as daily dose administered at steady-state. Overall treatment response rate was 72%, and the incidence of ADR was 30%. The logistic regression showed that exposure

  19. Uso de un Líquido Iónico como Catalizador para la Oxidación de Alcoholes Hidrofóbicos de Alto Peso Molecular The Use of an Ionic Liquid Catalyst for the Oxidation of Hydrophobic High Molecular Weight Alcohols

    Directory of Open Access Journals (Sweden)

    Nadia Guajardo

    2010-01-01

    Full Text Available Se realizaron pruebas de oxidación del docosanol hacia su respectivo ácido en un reactor discontinuo, usando un líquido iónico como catalizador compuesto por el catión Aliquat®336 y el anión poliperoxometalato {PO4[WO(O22]4}3-. Los resultados obtenidos permiten inferir que solo el agua oxigenada puede ser utilizado efectivamente como agente oxidante y confirmando la efectiva transferencia del oxigeno activo entre las fases acuosa y orgánica, además se constató que el paso limitante de la reacción global corresponde a la conversión del docosanol hacia el intermedio reacción (aldehído para la cual se estimó una constante cinética de 0,26 L mole-1 h-1 mientras que la cinética de la posterior oxidación hacia el ácido fue estimada en 1,3 L mole-1 h-1 (ambas a 90 °C. Luego de 6 horas de reacción a 90°C fueron obtenidas conversiones máximas de 81% y selectividads de 55%, operando con una relación molar H2O2/alcohol igual a 3 y relación másica alcohol/catalizador igual a 100.Catalytic batch oxidation runs of an hydrophobic high molecular weight alcohol (docosanol to the acid were performed using a functionalized ionic liquid composed by an Aliquat®336 cation and a polyperoxometalate {PO4[WO(O22]4}3- anion as a catalyst. The active oxygen is efficiently transferred by the catalyst from the aqueous to the alcoholic phase in accordance with an experimentally validated reaction scheme. Only the hydrogen peroxide was used effectively as an oxidant, giving an 81 % conversion and a 55% yield after 6 hours at 90ºC, with a H2O2/alcohol molar ratio that equal 3 and an alcohol/catalyst mass ratio that equal 100. The calculated kinetic constants, at 90ºC, for the docosanol oxidation to the aldehyde intermediate and the further oxidation towards docosanoic acid were 0,26 and 1,3 L mole-1 h-1, respectively.

  20. Organic carbon export to the deep Canada Basin: Importance of lateral supply

    Science.gov (United States)

    Hwang, J.; Eglinton, T. I.; Manganini, S. J.; Krishfield, R. A.; Griffith, D. R.; Honjo, S.; McLaughlin, F. A.; MacDonald, R. W.

    2010-12-01

    Understanding the processes driving the carbon cycle in the Arctic Ocean is of fundamental importance for assessing the impacts of the predicted climate change in this critical region. We analyzed sinking particle samples intercepted below the marginal ice zone of the Beaufort Sea at a depth of 3067m (Station A, 75N, 150W) in the Canada Basin from 2004 to 2005 and from 2007 to 2009, in order to examine interannual variability in carbon export to the bathypelagic zone. Sinking particles were also collected at other depths-2000m and 3750m- at Station A and from other locations (Station B-78N, 150W, and Station D-74N, 140W) within the basin for the latter time period. Prior observations from the 2004-5 study revealed that mass flux variations were temporally decoupled from the cycle of primary productivity in surface waters, and that sinking particle composition was characterized by old organic carbon (mean 14C age = ~ 1900 14C years) and abundant lithogenic material (~80%), implying supply via lateral advection from the surrounding margins (Hwang et al., 2008). Observations at Station A from 2007-9 reveal a similar mode of particle supply suggesting that lateral advection of resuspended sediment is a persistent feature in the southwest Canada Basin. Particle fluxes at three depths at Station A were similar with only slightly higher values at 50 m above the bottom, implying that lateral transport occurs throughout the lower water column. Particle flux and Δ14C values exhibited a negative correlation. Particle flux and Δ14C results also reveal interannual variability and spatial heterogeneity. A marked particle flux maximum was observed at Station A in August 2008 that was not seen in the prior deployments of 2004 and 2007. Extremely low Δ14C values for this late summer flux maximum implies that sediment resuspension and lateral advection, instead of enhanced summer time primary production in the overlying water column, was responsible. Particle flux was the highest

  1. Incorporation of international virtual teams as a complementary component to the traditional educational model Incorporación de virtual teams internacionales como componente complementario al modelo educativo tradicional

    Directory of Open Access Journals (Sweden)

    Carlos Fernando Arbeláez

    2012-08-01

    Full Text Available The model of virtual teams in higher education is being increasingly recognized as a phenomenon of great value to students about learning environments in the real world (Hsieh, Jang, Hwang, & Chen, 2011. Meanwhile, today’s environment requires from educational institutions dedicated to instruction undergraduate and graduate students, a rapid evolution of their models of teaching in order to conform to the same speed with which all fields transform in knowledge. This paper discusses the inclusion of virtual teams in the top-level educational models, meaning that incorporation as an option applies to all educational institutions, and above all, to their learning traditional structures. In this sense, the document includes analysis of relevant academic literature and data collected through interviews, conducted at six higher education faculty, who work in virtual teams schemes globally.El modelo de virtual teams en la educación superior está siendo reconocido cada vez máscomo un fenómeno de gran valor que acerca a los estudiantes a ambientes de aprendizajeen el mundo real (Hsieh, Jang, Hwang, & Chen, 2011. Por su parte, el entorno de hoyexige a las instituciones educativas dedicadas a la formación profesional en pregrado y posgrado, una rápida evolución de sus modelos de enseñanza a fin de ajustarlos a la mismavelocidad con la que se transforman todos los campos relacionados con el conocimiento.Este documento analiza la inclusión de virtual teams en los modelos educativos denivel superior, entendiendo dicha incorporación como una opción aplicable a todas lasinstituciones educativas, y sobre todo, a sus estructuras tradicionales de aprendizaje.En ese sentido, el documento incluye análisis de publicaciones académicas relevantes ydatos recopilados a través de entrevistas en profundidad, realizadas a seis profesores deeducación superior, quienes trabajan en esquemas de virtual teams a nivel global.

  2. Brow archetype preferred by Korean women.

    Science.gov (United States)

    Kim, Seong Kee; Cha, Seung Hyun; Hwang, Kun; Hwang, Se Won; Kim, Young Suk

    2014-07-01

    The aim of this study is to see which brow archetype is preferred by Korean women. The archetypes were chosen from a literature search, which contain detailed, replicable methods and have diagrams (Westmore, Lamas, Anastasia, Schreiber, and Hwang). A survey was conducted on 300 subjects (group A, 100 female medical students; group B, 100 women who had visited a plastic surgery clinic for periorbital rejuvenation; and group C, 100 women who visited the brow bar). They were asked whether they think there might be a method that yields an ideal brow archetype. In the cases where they said yes, they were asked to choose 1 of the illustrated 5 brow archetypes that they think is ideal. Among the 300 respondents, 232 (77.3%) thought there might be a method to yield an ideal brow archetype, whereas 68 (22.7%) answered they did not. The preference for the brow archetypes was different among the 5 archetypes (P = 0.0001, χ2). Anastasia was the most preferred (44.8%, brow starts on a perpendicular line drawn from the middle of the nostril, arches on a line drawn from the center of the nose through the center of the pupil, and ends on a line drawn from the edge of the corresponding nasal ala through the outer edge of the eye). Anastasia was followed by Lamas (22.0%). In group A, Anastasia (55.7%) was the most preferred, followed by Lamas (26.2%) and Westmore (13.1%). In group B, Anastasia (34.8%) was the most preferred, followed by Lamas (30.3%) and Westmore and Schreiber (both 13.5%). In group C, Anastasia (47.6%) was the most preferred, followed by Hwang (25.5%) and Westmore (11.0%). There was a significant difference (P archetype and occupation (P = 0.0033). However, no significant differences were noted for the preference of brow archetype between the age groups of younger than 30 years and older than 30 years (P = 0.1374), level of education (P = 0.3403), marital status (P = 0.541), or monthly income (P = 0.1696, χ2). The result of this study might be useful in facial

  3. Hospital discharge variation trend analysis of disease in patients with mental disorders%某医院出院精神障碍患者疾病构成变化趋势分析

    Institute of Scientific and Technical Information of China (English)

    张迎锋; 和吟枫; 杨旭娇; 董亮

    2015-01-01

    Objective To understand the mental disorder patients disease constitutes a change trend,and provide reference for prevention and control of mental illness and strengthen the suk specialty construction. Methods On the kasic information and diagnos=tic categories and changes in our hospital in the years 2012-2014 patients were retrospectively studied and analyzed. Results Of 3 years,of which the hospital patients in 10476 cases,men accounted for 57. 65%,women accounted for 42. 35%,70% patients age ketween 21~50 years old. Repeatedly hospitalized patients ratio increased from 13. 61% to 16. 10%. Mental and kehavioural disor=ders and schizophrenia caused ky alcohol is always the top two diseases,mental and kehavioral disorders caused ky alcohol ratio in=creased from 16. 48% to 19. 01%,kipolar disorder constituent ratio increased from 7. 71% to 15. 73%,krain damage and function disorder and other mental disorders constituent ratio increased from 2. 01% to 4. 57%. Conclusion The mental and kehavioral disor=ders and schizophrenia caused ky alcohol is always the focus of service in our hospital,kipolar affective disorder and krain damage and dysfunction as well as physical disease caused ky other mental disorders than there is an upward trend in our hospital,should strengthen the suk specialty construction.%目的了解精神障碍出院患者疾病构成变化趋势,为防治精神疾病和加强亚专科建设提供参考依据。方法对云南省大理州第二人民医院2012年-2014年出院患者的基本信息和疾病构成情况及其变化情况进行比较。结果3年来,我院出院患者共10476例,其中,男性占57.65%,女性占42.35%;年龄21~50岁有70%。多次住院的患者比例由13.61%上升到16.10%。精神分裂症与使用酒精所致的精神和行为障碍始终为前两位疾病,使用酒精所致的精神和行为障碍构成比由16.48%上升到19.01%,双相情感障碍构成比由7.71%上升到15.73%,脑损害和功能

  4. Effect of hydroxyapatite-containing microspheres embedded into three-dimensional magnesium phosphate scaffolds on the controlled release of lysozyme and in vitro biodegradation

    Directory of Open Access Journals (Sweden)

    Lee JM

    2014-09-01

    Full Text Available Jongman Lee, Hui-suk YunPowder and Ceramics Division, Korea Institute of Materials Science, Changwon, Republic of KoreaAbstract: The functionality of porous three-dimensional (3D magnesium phosphate (MgP scaffold was investigated for the development of a novel protein delivery system and biomimetic bone tissue engineering scaffold. This enhancement can be achieved by incorporation of hydroxyapatite (HA-containing polymeric microspheres (MSs into a bulk MgP matrix, and a paste-extruding deposition (PED system. In this work, the amount of MS and HA was precisely controlled when manufacturing MS-embedded MgP (MS/MgP composite scaffolds. The main influence was researched in terms of in vitro lysozyme-release, in vitro biodegradation, mechanical properties, and in vitro calcification. The controlled release of lysozyme was indicated, while showing graded release patterns according to HA content. The composite scaffolds degraded gradually with MS content and degradation time. Due to the effect of HA inclusion, the higher HA-containing MS/MgP scaffolds could, not only delay the biodegradation process but also, compensate for the possible loss of mechanical properties. In this regard, it is reasonable to confirm the inverse relationship between biodegradation and corresponding compressive properties. In order to encourage bioactivity and osteoconductivity, the MS/MgP composite scaffolds were subjected to simulated body fluid treatment. Calcium deposition was, in turn, improved with increasing MS and HA content over time. This quantitative result was also proved using morphological and elemental analysis. In summary, a significant transformation of a monolithic MgP scaffold was directed toward a multifunctional bone tissue engineering scaffold equipped with controlled protein delivery, biodegradability, and bioactivity.Keywords: protein delivery, bone tissue engineering

  5. Growth responses of Picea mongolica seedlings to defoliation rate

    Institute of Scientific and Technical Information of China (English)

    ZOU Chun-jing; HAN Shi-jie; QI Shu-yan; XU Wen-duo; LI Dao-tang

    2005-01-01

    Picea mongolica W. D. Xu. is an endemic species in China. The spruce forest is only found in semi-arid habitat in Inner Mongolia Autonomous Region of China. Based on the simulative defoliation experiment, it was proved that Picea mongolica seedlings had the compensatory and overcompensatory effects under the certain defoliation rate. The results of variance analysis on growth indexes showed that in PM Ⅰ (natural regeneration seedlings under Picea mongolica forest), the differences of H1 (height in June 23) and H2 (height in September 3) were extremely significant, and the difference of D(diameter at the breast height) were not significant. In PM Ⅱ (artificial regeneration seedlings under Betula platyphylla Suk. forest), the difference of H1 was significant, the difference of H2 was not significant, and the difference of D was extremely significant. The regression equations were established and the compensatory and overcompensatory points were obtained. In PM Ⅰ , the compensatory points of H1, H2, and D were 0.7628, 0.7436, 0.5725, and the overcompensatory points were 0.6056, 0.5802 and 0.2909 respectively. In PM Ⅱ, the compensatory points of H1, H2, and D are 0.5012, 0.3421, 0.2488, and the overcompensatory points are 0.4137, 0.2633 and 0.0747 respectively. These results suggested that the induction of compensatory growth mechanisms in spruce seedlings required a threshold level of defoliation, and the insects in Picea mongolica forest could be controlled in a certain degree.

  6. Measuring negative symptoms in patients with schizophrenia: reliability and validity of the Korean version of the Motivation and Pleasure Scale-Self-Report

    Directory of Open Access Journals (Sweden)

    Kim JS

    2016-05-01

    Full Text Available Ji-Sun Kim,1 Seon-Kyeong Jang,1 Seon-Cheol Park,2 Jung-Seo Yi,3 Joong-Kyu Park,4 Jung Suk Lee,5 Kee-Hong Choi,6 Seung-Hwan Lee1,7 1Clinical Emotion and Cognition Research Laboratory, Goyang, 2Department of Psychiatry, Inje University Haeundae Paik Hospital, Busan, 3Department of Psychiatry, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 4Department of Rehabilitation Psychology, Daegu University, Daegu, 5Department of Psychiatry, National Health Insurance Service Ilsan Hospital, Goyang, 6Department of Psychology, Korea University, Seoul, 7Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea Background: The Clinical Assessment Interview for Negative Symptoms (CAINS is one of the validated interview measures of negative symptoms in psychotic disorders. The Motivation and Pleasure Scale-Self-Report (MPSR is a self-report measure that assesses the motivation and pleasure domains of negative symptoms based on the CAINS. This study evaluated the reliability and validity of a Korean version of the MPSR.Methods: A total of 139 patients with schizophrenia completed the MPSR, CAINS, Scale for the Assessment of Negative Symptoms (SANS, Brief Psychiatric Rating Scales, Calgary Depression Scale for Schizophrenia, and other measures of trait and cognitive function.Results: The 15-item MPSR showed good internal consistency. In addition, it also had a good convergent validity with the Motivation and Pleasure subscale of the CAINS and the anhedonia/avolition subscale of the SANS. The scale was not associated with psychotic symptoms, agitation/mania, and depression/anxiety, and it showed good discriminant validity. MPSR scores were significantly correlated with Behavioral Activation System total score for trait measure.Conclusion: The Korean version of the MPSR is a notable self-report method for examining the severity of negative symptoms in schizophrenia. Keywords: Korean

  7. Neuroprotection and acidosis induced by cortical spreading depression

    Directory of Open Access Journals (Sweden)

    Kwong KK

    2016-12-01

    Full Text Available Kenneth K Kwong, Suk-tak Chan Department of Radiology, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD triggered uncoupling protein-5 (UCP-5,1 which had been reported to exert a long-term effect upon neuron protection.2 The result is another piece in CSD literature on modifying gene expressions to provide neuroprotection to subsequent ischemic episodes.3,4 Authors' replyGiovanni Messina1,2Emanuela Viggiano1,3Vincenzo Monda1Antonietta Messina1Fiorenzo Moscatelli2Anna Valenzano2Domenico Tafuri4Vincenzo De Luca5Giuseppe Cibelli2Marcellino Monda1 1Section of Human Physiology and Unit of Dietetic and Sport Medicine, Department of Experimental Medicine, Second University of Naples, Caserta, 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia, 3Department of Medicine, University of Padua, Padua, 4Department of Motor Sciences and Wellness, University of Naples “Parthenope,” Napoli, Italy; 5Department of Psychiatry, University of Toronto, Toronto, ON, Canada Thank you for the attention paid to our article entitled: “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5”.1 We do agree that cerebral spreading depression (CSD-induced acidosis is an intriguing aspect of the neuroprotection puzzle. It is well known that CSD is involved in the pathophysiology of migraine, cerebral ischemia, subarachnoid hemorrhage, and traumatic brain injury.2–7 View the original paper by Viggiano and colleagues. 

  8. Early results of pediatric appendicitis after adoption of diagnosis-related group-based payment system in South Korea

    Directory of Open Access Journals (Sweden)

    Moon SB

    2015-11-01

    Full Text Available Suk-Bae MoonDepartment of Surgery, Kangwon National University Hospital, Kangwon National School of Medicine, Kangwon National University, Chuncheon, South KoreaPurpose: As an alternative to the existing fee-for-service (FFS system, a diagnosis-related group (DRG-based payment system has been suggested. The aim of this study was to investigate the early results of pediatric appendicitis treatment under the DRG system, focusing on health care expenditure and quality of health care services.Patients and methods: The medical records of 60 patients, 30 patients before (FFS group, and 30 patients after adoption of the DRG system (DRG, were reviewed retrospectively.Results: Mean hospital stay was shortened, but the complication and readmission rates did not worsen in the DRG. Overall health care expenditure and self-payment decreased from Korean Won (KRW 2,499,935 and KRW 985,540, respectively, in the FFS group to KRW 2,386,552 and KRW 492,920, respectively, in the DRG. The insurer’s payment increased from KRW 1,514,395 in the FFS group to KRW 1,893,632 in the DRG. For patients in the DRG, calculation by the DRG system yielded greater overall expenditure (KRW 2,020,209 vs KRW 2,386,552 but lower self-payment (KRW 577,803 vs KRW 492,920 than calculation by the FFS system.Conclusion: The DRG system worked well in pediatric patients with acute appendicitis in terms of cost-effectiveness over the short term. The gradual burden on the national health insurance fund should be taken into consideration.Keywords: appendicitis, child, fee-for-service plans, diagnosis-related groups, quality of health care, health care expenditures

  9. [The early medical textbooks in Korea: medical textbooks published at Je Joong Won-Severance Hospital Medical School].

    Science.gov (United States)

    Park, H W

    1998-01-01

    Kwang Hye Won(Je Joong Won), the first western hospital in Korea, was founded in 1885. The first western Medical School in Korea was open in 1886 under the hospital management. Dr. O. R. Avison, who came to Korea in 1893, resumed the medical education there, which was interrupted for some time before his arrival in Korea. He inaugurated translating and publishing medical textbooks with the help of Kim Pil Soon who later became one of the first seven graduates in Severance Hospital Medical School. The first western medical textbook translated into Korean was Henry Gray's Anatomy. However, these twice-translated manuscripts were never to be published on account of being lost and burnt down. The existing early anatomy textbooks, the editions of 1906 and 1909, are not the translation of Gray's Anatomy, but that of Japanese anatomy textbook of Gonda. The remaining oldest medical textbook in Korean is Inorganic Materia Medica published in 1905. This book is unique among its kind that O. R. Avison is the only translator of the book and it contains the prefaces of O. R. Avison and Kim Pil Soon. The publication of medical textbook was animated by the participation of other medical students, such as Hong Suk Hoo and Hong Jong Eun. The list of medical textbooks published includes almost all the field of medicine. The medical textbooks in actual existence are as follows: Inorganic Materia Medica (1905), Inorganic Chemistry (1906), Anatomy I (1906), Physiology (1906), Diagnostics I (1906), Diagnostics II (1907), Obstetrics (1908), Organic Chemistry (1909), Anatomy (1909), and Surgery (1910).

  10. Comprehensive transcriptome analysis of developing xylem responding to artificial bending and gravitational stimuli in Betula platyphylla.

    Directory of Open Access Journals (Sweden)

    Chao Wang

    Full Text Available Betula platyphylla Suk (birch is a fast-growing woody species that is important in pulp industries and the biofuels. However, as an important pulp species, few studies had been performed on its wood formation. In the present study, we investigated the molecular responses of birch xylem to artificial bending and gravitational stimuli. After trunks of birch trees were subjected to bending for 8 weeks, the cellulose content was significantly greater in tension wood (TW than in opposite wood (OW or normal wood (NW, whereas the lignin content in TW was significantly lower than that in OW and NW. In addition, TW grew more rapidly than OW and generated TW-specific fibers with an additional G-layer. Three transcriptome libraries were constructed from TW, OW and NW of B. platyphylla, respectively, after the plants were subjected to artificial bending. Overall, 80,909 nonredundant unigenes with a mean size of 768 nt were assembled. Expression profiles were generated, and 9,684 genes were found to be significantly differentially expressed among the TW, OW and NW libraries. These included genes involved in secondary cell wall structure, wood composition, and cellulose or lignin biosynthesis. Our study showed that during TW formation, genes involved in cellulose synthesis were induced, while the expression of lignin synthesis-related genes decreased, resulting in increased cellulose content and decreased lignin levels in TW. In addition, fasciclin-like arabinogalactan proteins play important role in TW formation. These findings may provide important insights into wood formation at the molecular level.

  11. Diarylheptanoids from leaves of Betula platyphylla%白桦叶中的二苯基庚烷类化合物

    Institute of Scientific and Technical Information of China (English)

    王素娟; 裴月湖

    2001-01-01

    目的对白桦叶的化学成分做系统研究,以更好的开发利用我国的植物资源。方法采用硅胶柱、凝胶柱及制备薄层色谱法进行分离,通过波谱技术(1HNMR,13CNMR,1H-1HCOSY,HMQC,HMBC,NOESY)进行结构鉴定。结果分离鉴定了4种二苯基庚烷类化合物,槭木素丁(Ⅰ),氧杂二苯庚烯(Ⅱ),17-甲基-15-甲氧基-7-氧代槭木素丁(Ⅲ),槭木素十一(Ⅳ)。结论化合物Ⅲ,Ⅳ均首次从本种植物中分离得到,并纠正了化合物Ⅲ的碳谱数据归属。%Object To study the chemical consti tuents of Betula platyphyllaSuk. for the better deve-lopmen t an d utilization of botanic resources of our country. Methods The constituents were isolated by column chromatography (silica gel and Sephadex LH 20) and preparative TLC, and identified by means of spectral data (1HNMR, 13CNMR, 1H-1HCOSY, HMQC, HMBC, NOESY). Resu lts 4 diarylheptanoids were obtained and elucidated as acerogenin E (Ⅰ ), (3R)-3, 5′-dihydroxy-4′-methoxy-3′, 4″-oxo-l, 7-diphenyl-l-hep te ne (Ⅱ), 15-methoxy-17-O-methyl-7-oxoacerogenin E (Ⅲ), ac erogenin K (Ⅳ). Conclusion Compounds Ⅲ and Ⅳ were isolated for the first time from this plant and the assignment of 13CNMR data o f compound Ⅲ was corrected.

  12. Nitrogen requirements of cassava in selected soils of Thailand

    Directory of Open Access Journals (Sweden)

    Jakchaiwat Kaweewong

    2013-08-01

    Full Text Available Cassava (Manihot esculenta is one of the most important export crops in Thailand, yet the nitrogen requirement is unknown and not considered by growers and producers. Cassava requirements for N were determined in field experiments during a period of four years and four sites on the Satuk (Suk, Don Chedi (Dc, Pak Chong (Pc,and Ban Beung (BBg soil series in Lopburi, Supanburi, Nakhon Ratchasima, and Chonburi sites, respectively. The fertilizer treatment structure comprised 0, 62.5, 125, 187.5, 250 and 312.5 kg N ha^(-1 as urea. At each site cassava was harvested at nine months and yield parameters and the minimum datasets were taken. The fertilizer rate which resulted in maximum yield ranged from 187.5 kg N ha^(-1 in Supanburi and Chonburi (fresh weight yield of 47,500 and 30,000 kg ha^(-1 respectively to 250 kg N ha^(-1 in Lopburi and Nakhon Ratchasima (fresh weight yield of 64,100 and 46,700 kg ha^(-1 respectively. Yield appeared to decrease at the higher, 312 kg ha^(-1, at Supanburi and Lopburi, and 250 kg ha^(-1 (Chonburi fertilizer N rates. Net revenue was 70.4 and 72.9 % higher than where no N was appliedLopburi and Nakhon Ratchasima sites. Net revenue at the Supanburi and Chonburi sites were 53.8 and 211.0 % higher than that where no N was applied. This study suggests that at all sites improved cassava production and net revenue could be obtained with the judicious application of higher quantities of N. The results provide needed guidance to nitrogen fertilization of the important industrial crop cassava in Thailand.

  13. 一种高斯曲率策动和高阶微分相融合的去噪方法%A Fusion Denoising Method Based on Both Gaussian Curvature-driven and Differential of Higher Order

    Institute of Scientific and Technical Information of China (English)

    王艳红; 李维国

    2009-01-01

    Lee Suk-Ho和Seo Jin Keun提出的基于高斯曲率的去噪方法在处理低梯度区域时,虽然对于保留图像的细节特征非常有效,但是步长选择稍大时,会产生黑白点,过小又会增加迭代次数.针对此问题,提出了一种用Tukey's biweight函数来控制曲率扩散的修正模型,该模型可以在较大时间步长的情况下避免黑白点的出现.进一步,为了利用高阶去噪方法对高梯度区域进行快速去噪,提出了一种将高斯曲率去噪方程和四阶偏微分方程相融合的去噪模型,以便可以根据具体的图像合理地分配两部分的权重.数值实验证明,该模型不仅可以处理曲面拟合方法所不能消除的椒盐噪声,而且可以实现两种方法的优点互补,既能保持边界,又较好地保留了细节特征.

  14. Lumbar spondylolisthesis treated with lnterbody fusion cage and posteriotaterior lumbar bone graft%椎间融合器联合后外侧植骨融合治疗腰椎滑脱症

    Institute of Scientific and Technical Information of China (English)

    黄永栋; 蒋卫平; 韦冰丹; 杨晓明; 甘坤宁; 周竖平; 刘剑伟; 黄家志

    2012-01-01

    Objective To evaluate the Affiliated to clinical outcome of lumbar spondylolisthesis using hiterbody fusion cage and posteriolalerion lumbar bone graft. Methods From January 2007 to January 2011,32 cases of lumbar spondylolisthesis were treated with lnterbody fusion cages and posteriolaterion lumbar bone graft. Results ['oilowed—up for 12 to 38 months.averaged 3.6 months, the fusion rate was 100%. According lo evaluation standard of ZOU De-wei;19 cases achieved excellent outcomes.good 10 and 3 fair,the clinical satisfaction rate of 90,62%, Conclusions The lnterbody fusion cages and posteriolaterion lumbar bone graft is a effective method for keeping spinal stability and restoring inlerverlebral height and improving the bony fusion rale.%目的 探讨椎间融合器联合后外侧植骨融合治疗腰椎滑脱的术后效果.方法 2007-01-2011-01 采用椎间植骨联合后外侧植骨融合治疗腰椎滑脱患者32 例.结果 随访12~38 月,平均16 个月,根据Suk 方法判定术后骨融合情况,骨融合率为100%.根据邹德威等临床功能评价标准评分:优19 例,良10 例,可3 例,优良率90.62%.结论 椎间融合器联合后外侧植骨融合术治疗腰椎滑脱是一种较理想的手术方法,能维持脊柱稳定性,恢复椎间隙高度和提高植骨融合率.

  15. 白桦APETALA2( AP2)转录因子基因的分离及其表达%Isolation and Expression of APETALA2 Transcription Factor Gene in Betula platyphylla

    Institute of Scientific and Technical Information of China (English)

    张妍; 刘瀛; 孙丰宾; 戴超; 刘雪梅

    2012-01-01

    AP2 gene is a key transcription factor involved in flower development in plants. The full cDNA of AP2 gene was isolated from Betula platyphylla Suk. by methods of reverse transcription polymerase chain reaction ( RT-PCR) and 5' and 3' rapid amplification of cDNA ends (RACE) . Results showed that AP2 gene contains an open reading frame (ORF) ,of 1554bp encoding 517 amino acids. Molecular weight of the deduced protein of BpAPl is 56.74kDa and the theoretical isoelectric point is 6. 34. The AP2 functional sites and characterized domains were confirmed in the sequence, so the isolated gene was named as BpAPl, and registered in Gen Bank with accession number JN247408. The deduced amino acid sequence shared 51%~77% of identity with other twelve plant species, the maximum identity with Arabidopsis thaliana (77% ) and minimum identity with Pinus thunbergii (51% ). A phylogenetic tree was constructed according to multiple sequences alignment of all the thirteen plant species. Transcription expression of BpAPl was analyzed by qRT-PCR in different tissues and periods in B. platyphylla. Results showed that BpAPl was more highly expressed in floral organs than in vegetative organs, expression quantity more highly in young tissues than in mature tissues. It inferred that BpAP2 transfactor involved in the regulation of development of floral organs and meristematic tissues in Betula. In addition, a natural male inflorescence- abnormal mutant of B. platyphylla was used for transcription analysis of BpAP2. Results showed that BpAPl gene is expressed up-regulatedly in female inflorescences, while down-regulation in male inflorescences, young leaves and young shoots, which predicted that BpAPl should be involved in regulation and expression of multiple genes, and not only be involved in the development of floral organs, but also play some roles in the development of vegetative tissues.

  16. X-rays from the oxygen-type Wolf-Rayet binary WR30a

    CERN Document Server

    Zhekov, S A

    2015-01-01

    We present an analysis of XMM-Newton X-ray data of WR30a (WO+O), a close massive binary that harbours an oxygen-rich Wolf-Rayet star. Its spectrum is characterized by the presence of two well-separated broad peaks, or `bumps', one peaking at energies between 1 and 2 keV and the other between 5 and 7 keV. A two-component model is required to match the observed spectrum. The higher energy spectral peak is considerably more absorbed and dominates the X-ray luminosity. For the currently accepted distance of 7.77 kpc, the X-ray luminosity of WR30a is L_X > 10^{34} erg s^{-1}, making it one of the most X-ray luminous WR+O binary amongst those in the Galaxy with orbital periods less than ~20 d. The X-ray spectrum can be acceptably fitted using either thermal or nonthermal models, so the X-ray production mechanism is yet unclear.

  17. From crops to products for crops: preserving the ecosystem through the use of bio-based molecules

    Directory of Open Access Journals (Sweden)

    Godard Anaïs

    2016-09-01

    Full Text Available In a context of dwindling oil reserves and environmental pressures, the chemical industry needs to innovate by developing new processes for producing bioproducts from raw plant materials. Unsaturated fatty acids from vegetable oils constitute a highly promising renewable resource that can be used to diversify productions, decreasing reliance on petroleum. A starting material rich in oleic acid has been obtained through the selection of high-oleic sunflower varieties and enzymatic hydrolysis of the oil they produce. The double bonds of this unsaturated raw material have been cleaved in green oxidizing conditions involving a biphasic lipophilic-aqueous system including hydrogen peroxide as an oxidant and a peroxo-tungsten complex Q3 {PO2[WO(O22]4} as a phase-transfer catalyst (PTC and co-oxidant. This PTC efficiently transferred oxygen to the substrate in the lipophilic phase. A mono-acid (pelargonic acid and a di-acid (azelaic acid, with shorter, unusual hydrocarbon chains not present in the natural state, were synthesized and purified through an intensive process. Pelargonic acid was then formulated as an environmentally friendly biocontrol agent for weeds. We extended this green process of oxidative scission to other fatty acids and derivatives, to obtain other short-chain acids with diverse potential applications. This production chain (crops, reaction and purification processes, products, applications is based on a sustainable development strategy.

  18. De Novo Transcriptome Analysis of Cucumis melo L. var. makuwa.

    Science.gov (United States)

    Kim, Hyun A; Shin, Ah-Young; Lee, Min-Seon; Lee, Hee-Jeong; Lee, Heung-Ryul; Ahn, Jongmoon; Nahm, Seokhyeon; Jo, Sung-Hwan; Park, Jeong Mee; Kwon, Suk-Yoon

    2016-02-01

    Oriental melon (Cucumis melo L. var. makuwa) is one of six subspecies of melon and is cultivated widely in East Asia, including China, Japan, and Korea. Although oriental melon is economically valuable in Asia and is genetically distinct from other subspecies, few reports of genome-scale research on oriental melon have been published. We generated 30.5 and 36.8 Gb of raw RNA sequence data from the female and male flowers, leaves, roots, and fruit of two oriental melon varieties, Korean landrace (KM) and Breeding line of NongWoo Bio Co. (NW), respectively. From the raw reads, 64,998 transcripts from KM and 100,234 transcripts from NW were de novo assembled. The assembled transcripts were used to identify molecular markers (e.g., single-nucleotide polymorphisms and simple sequence repeats), detect tissue-specific expressed genes, and construct a genetic linkage map. In total, 234 single-nucleotide polymorphisms and 25 simple sequence repeats were screened from 7,871 and 8,052 candidates, respectively, between the KM and NW varieties and used for construction of a genetic map with 94 F2 population specimens. The genetic linkage map consisted of 12 linkage groups, and 248 markers were assigned. These transcriptome and molecular marker data provide information useful for molecular breeding of oriental melon and further comparative studies of the Cucurbitaceae family.

  19. Editorial: Focus on Extra Space Dimensions

    Science.gov (United States)

    Agashe, Kaustubh; Pomarol, Alex

    2010-07-01

    Experiments at the Large Hadron Collider (LHC) have just started. In addition to verifying the Standard Model (SM) of particle physics, these experiments will probe a new energy frontier and test extensions of the SM. The existence of extra dimensions is one of the most attractive possibilities for physics beyond the SM. This focus issue contains a collection of articles addressing both theoretical and phenomenological aspects of extra-dimensional models. Focus on Extra Space Dimensions Contents Minimal universal extra dimensions in CalcHEP/CompHEP AseshKrishna Datta, Kyoungchul Kong and Konstantin T Matchev Disordered extra dimensions Karim Benakli Codimension-2 brane-bulk matching: examples from six and ten dimensions Allan Bayntun, C P Burgess and Leo van Nierop Gauge threshold corrections in warped geometry Kiwoon Choi, Ian-Woo Kim and Chang Sub Shin Holographic methods and gauge-Higgs unification in flat extra dimensions Marco Serone Soft-wall stabilization Joan A Cabrer, Gero von Gersdorff and Mariano Quirós Warped five-dimensional models: phenomenological status and experimental prospects Hooman Davoudiasl, Shrihari Gopalakrishna, Eduardo Pontón and José Santiago

  20. Hearing Mouth Shapes: Sound Symbolism and the Reverse McGurk Effect

    Directory of Open Access Journals (Sweden)

    Charles Spence

    2012-09-01

    Full Text Available In their recent article, Sweeny, Guzman-Martinez, Ortega, Grabowecky, and Suzuki (2012 demonstrate that heard speech sounds modulate the perceived shape of briefly presented visual stimuli. Ovals, whose aspect ratio (relating width to height varied on a trial-by-trial basis, were rated as looking wider when a /woo/ sound was presented, and as taller when a /wee/ sound was presented instead. On the one hand, these findings add to a growing body of evidence demonstrating that audiovisual correspondences can have perceptual (as well as decisional effects. On the other hand, they prompt a question concerning their origin. Although the currently popular view is that crossmodal correspondences are based on the internalization of the natural multisensory statistics of the environment (see Spence, 2011, these new results suggest instead that certain correspondences may actually be based on the sensorimotor responses associated with human vocalizations. As such, the findings of Sweeny et al. help to breathe new life into Sapir's (1929 once-popular “embodied” explanation of sound symbolism. Furthermore, they pose a challenge for those psychologists wanting to determine which among a number of plausible accounts best explains the available data on crossmodal correspondences.

  1. Boomers versus Millennials: Online Media Influence on Media Performance and Candidate Evaluations

    Directory of Open Access Journals (Sweden)

    Terri Towner

    2016-09-01

    Full Text Available Facebook posts, YouTube videos, tweets and wooing political bloggers have become standard practice in marketing political campaigns. Research has demonstrated the effect of new media on a host of politically-related behavior, including political participation, knowledge acquisition, group formation and self-efficacy. Yet, issues related to media trust, media performance and candidate evaluations have not been fully explored. In addition, much of the political marketing research looks exclusively at the Millennial age cohort, ignoring other age groups, particularly Baby Boomers. This case study addresses whether attention to traditional (i.e., television, hard-copy newspapers and radio and online media sources (i.e., political candidate websites, television network websites, online newspapers, Facebook, Twitter, YouTube, Tumblr and political blogs about the 2012 U.S. presidential campaign influences Millennials and Baby Boomers’ media trust and performance ratings, as well as candidate evaluations. Panel surveys were completed by both age cohorts, Millennials (n = 431 and Baby Boomers (n = 360, during the last two weeks of the presidential election. Findings indicate that traditional sources, specifically television, rather than online sources are significantly linked to media trust and performance ratings among both Boomers and Millennials. Attention to traditional media for campaign information predicts Boomers’ candidate evaluations, whereas Millennials’ candidate evaluations are influenced by online sources, such as Facebook and candidate websites.

  2. Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles

    Directory of Open Access Journals (Sweden)

    Naeem M

    2015-07-01

    Full Text Available Muhammad Naeem, Jiafu Cao, Moonjeong Choi, Woo Seong Kim, Hyung Ryong Moon, Bok Luel Lee, Min-Soo Kim, Yunjin Jung, Jin-Wook Yoo College of Pharmacy, Pusan National University, Busan, South Korea Abstract: Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive azo-polyurethane and pH-sensitive methacrylate copolymer for the treatment of colitis. The therapeutic potential of the enzyme/pH dual-sensitive nanoparticles was evaluated using a rat colitis model and compared to single pH-triggered nanoparticles. Clinical activity scores, colon/body weight ratios, myeloperoxidase activity, and proinflammatory cytokine levels were markedly decreased by dual-sensitive nanoparticles compared to single pH-triggered nanoparticles and budesonide solution. Moreover, dual-sensitive nanoparticles accumulated selectively in inflamed segments of the colon. In addition, dual-sensitive nanoparticle plasma concentrations were lower than single pH-triggered nanoparticles, and no noticeable in vitro or in vivo toxicity was observed. Our results demonstrate that enzyme/pH dual-sensitive nanoparticles are an effective and safe colon-targeted delivery system for colitis therapy. Keywords: azo-polyurethane, methacrylate copolymer, budesonide, colon-targeted nanoparticles, colitis

  3. The beneficial effects of honeybee-venom serum on facial wrinkles in humans

    Directory of Open Access Journals (Sweden)

    Han SM

    2015-10-01

    Full Text Available Sang Mi Han,1 In Phyo Hong,1 Soon Ok Woo,1 Sung Nam Chun,2 Kwan Kyu Park,3 Young Mee Nicholls,4 Sok Cheon Pak5 1Department of Agricultural Biology, National Academy of Agricultural Science, Wanju, 2Dong Sung Pharmaceuticals Co Ltd, Seoul, 3Department of Pathology, School of Medicine, Catholic University of Daegu, Daegu, South Korea; 4Manuka Doctor Ltd, Auckland, New Zealand; 5School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, Australia Abstract: Facial wrinkles are an undesirable outcome caused by extrinsic photodamage and intrinsic aging processes. Currently, no effective strategies are known to prevent facial wrinkles. We assessed the beneficial effects of bee-venom serum on the clinical signs of aging skin. Our results show that bee-venom serum treatment clinically improved facial wrinkles by decreasing total wrinkle area, total wrinkle count, and average wrinkle depth. Therefore, bee-venom serum may be effective for the improvement of skin wrinkles. Keywords: bee venom, wrinkle, area, count, depth

  4. Decontamination and decommissioning of the Mayaguez (Puerto Rico) facility

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, P.K.; Freemerman, R.L. [Bechtel National, Inc., Oak Ridge, TN (United States)

    1989-11-01

    On February 6, 1987 the US Department of Energy (DOE) awarded the final phase of the decontamination and decommissioning of the nuclear and reactor facilities at the Center for Energy and Environmental Research (CEER), in Mayaguez, Puerto Rico. Bechtel National, Inc., was made the decontamination and decommissioning (D and D) contractor. The goal of the project was to enable DOE to proceed with release of the CEER facility for use by the University of Puerto Rico, who was the operator. This presentation describes that project and lesson learned during its progress. The CEER facility was established in 1957 as the Puerto Rico Nuclear Center, a part of the Atoms for Peace Program. It was a nuclear training and research institution with emphasis on the needs of Latin America. It originally consisted of a 1-megawatt Materials Testing Reactor (MTR), support facilities and research laboratories. After eleven years of operation the MTR was shutdown and defueled. A 2-megawatt TRIGA reactor was installed in 1972 and operated until 1976, when it woo was shutdown. Other radioactive facilities at the center included a 10-watt homogeneous L-77 training reactor, a natural uranium graphite-moderated subcritical assembly, a 200KV particle accelerator, and a 15,000 Ci Co-60 irradiation facility. Support facilities included radiochemistry laboratories, counting rooms and two hot cells. As the emphasis shifted to non-nuclear energy technology a name change resulted in the CEER designation, and plans were started for the decontamination and decommissioning effort.

  5. The prevalence of Microfilaria spp. in primates of colombian zoos

    Directory of Open Access Journals (Sweden)

    Rosmery Ladino De La Hortúa

    2007-06-01

    Full Text Available The prevalence of Microfilaria spp in 266 human and non human primates of Colombian zoos located between 5 and 2850 meters over sea level (mosl was of 6.39% (17/266. Most of them were adult males Saguinus leucopus, Saguinus oedipus, Saimiri sciureus and Aotus sp; corresponding to Matecaña, Santa Fe and Santacruz zoos, located between 1.001-2.000 mosl. The microfilarias species observed in this study are morphologically compatible with Dipetalonema perstans and Microfilaria bolivarensis, using direct drop technique, Woo, extended of central blood and capillary dyed with Giemsa and Knott, The most sensible technique was extended of central blood dyed with Giemsa. The statistical program used was Epi info 6.1, to determinate prevalence by sex, age, species, zoo, technique and altitude, with a significance level of (P = 0.05. The Saguinus leucopus showed high quantities of microfilaremias with sickness signs, so they were considered reservoirs and / or porter of the microfilarias.

  6. An expanding sexual economy along National Route 3 in Luang Namtha Province, Lao PDR.

    Science.gov (United States)

    Doussantousse, Serge; Sakounnavong, Bounchanh; Patterson, Ian

    2011-12-01

    With some of the lowest development indicators in Southeast Asia, remote upland areas of the Lao People's Democratic Republic are among the poorest in the region. The advent of improved transport and communication links, along with opportunities for wage employment, have accelerated the growth of a cash economy in traditionally isolated farming communities of Luang Namtha Province. Interviews and focus group discussions with young people, women in the sexual service business and health workers indicate that the lure of the new economy is wooing villagers away from their agrarian roots. Motorbikes and mobile phones have expanded the sexual territory of indigenous youth at a time when international commerce and a cash economy along improved highways are bringing new people into the region. Among the concerns for their health and safety are at-risk behaviours involving alcohol and sexual practices, especially HIV and sexually transmitted infections. Of particular concern is the sexual trade in the province with a predominance of young, poorly educated Khmou women providing sexual services in a growing number of entertainment places.

  7. Study of the combined effect of temperature, pH and water activity on the radial growth rate of the white-rot basidiomycete Physisporinus vitreus by using a hyphal growth model

    CERN Document Server

    Fuhr, M J; Schubert, M; Schwarze, F W M R; Herrmann, H J

    2011-01-01

    The present work investigates environmental effects on the growth of fungal colonies of P. vitreus by using a lattice-free discrete modelling approach called FGM (Fuhr et al. (2010), arXiv:1101.1747), in which hyphae and nutrients are considered as discrete structures. A discrete modelling approach allows studying the underlying mechanistic rule concerning the basic architecture and dynamic of fungal networks on the scale of a single colony. By comparing simulations of the FGM with laboratory experiments of growing fungal colonies on malt extract agar we show that combined effect of temperature, pH and water activity on the radial growth rate of a fungal colony on a macroscopic scale may be explained by a power law for the growth costs of hyphal expansion on a microscopic scale. The information about the response of the fungal mycelium on a microscopic scale to environmental conditions is essential to simulate its behavior in complex structure substrates such as wood, where the impact of the fungus to the woo...

  8. Molecular dynamics simulations on the effect of size and shape on the interactions between negative Au18(SR)14, Au102(SR)44 and Au144(SR)60 nanoparticles in physiological saline.

    Science.gov (United States)

    Villareal, Oscar D; Rodriguez, Roberto A; Yu, Lili; Wambo, Thierry O

    2016-08-20

    Molecular dynamics simulations employing all-atom force fields have become a reliable way to study binding interactions quantitatively for a wide range of systems. In this work, we employ two recently developed methods for the calculation of dissociation constants KD between gold nanoparticles (AuNPs) of different sizes in a near-physiological environment through the potential of mean force (PMF) formalism: the method of geometrical restraints developed by Woo et al. and formalized by Gumbart et al. and the method of hybrid Steered Molecular Dynamics (hSMD). Obtaining identical results (within the margin of error) from both approaches on the negatively charged Au18(SR)14 NP, functionalized by the negatively charged 4-mercapto-benzoate (pMBA) ligand, we draw parallels between their energetic and entropic interactions. By applying the hSMD method on Au102(SR)44 and Au144(SR)60, both of them near-spherical in shape and functionalized by pMBA, we study the effects of size and shape on the binding interactions. Au18 binds weakly with KD = 13mM as a result of two opposing effects: its large surface curvature hindering the formation of salt bridges, and its large ligand density on preferential orientations favoring their formation. On the other hand, Au102 binds more strongly with KD = 30μM and Au144 binds the strongest with KD = 3.2nM.

  9. Gold nanoparticles promote osteogenic differentiation in human adipose-derived mesenchymal stem cells through the Wnt/β-catenin signaling pathway

    Directory of Open Access Journals (Sweden)

    Choi SY

    2015-07-01

    Full Text Available Seon Young Choi,1 Min Seok Song,1 Pan Dong Ryu,1 Anh Thu Ngoc Lam,2 Sang-Woo Joo,2 So Yeong Lee1 1Laboratory of Veterinary Pharmacology, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, 2Department of Chemistry, Soongsil University, Seoul, South Korea Abstract: Gold nanoparticles (AuNPs are attractive materials for use in biomedicine due to their physical properties. Increasing evidence suggests that several nanoparticles induce the differentiation of human mesenchymal stem cells into osteoblasts and adipocytes. In this study, we hypothesized that chitosan-conjugated AuNPs promote the osteogenic differentiation of human adipose-derived mesenchymal stem cells. For the evaluation of osteogenic differentiation, alizarin red staining, an alamarBlue® assay, and a quantitative real-time polymerase chain reaction analysis were performed. In order to examine specific signaling pathways, immunofluorescence and a western blotting assay were performed. Our results demonstrate that chitosan-conjugated AuNPs increase the deposition of calcium content and the expression of marker genes related to osteogenic differentiation in human adipose-derived mesenchymal stem cells at nontoxic concentrations. These results indicate that chitosan-conjugated AuNPs promote osteogenesis through the Wnt/β-catenin signaling pathway. Therefore, chitosan-conjugated AuNPs can be used as a reagent for promoting bone formation. Keywords: chitosan-conjugated gold nanoparticle, mineralization, nonphosphorylated beta-catenin

  10. Use of PROMIS for Patients Undergoing Primary Total Shoulder Arthroplasty.

    Science.gov (United States)

    Dowdle, S Blake; Glass, Natalie; Anthony, Chris A; Hettrich, Carolyn M

    2017-09-01

    The Patient-Reported Outcomes Measurement Information System (PROMIS) consists of question banks for health domains through computer adaptive testing (CAT). For patients with glenohumeral arthritis, (1) there would be high correlation between traditional patient-reported outcome (PRO) measures and the PROMIS upper extremity item bank (PROMIS UE) and PROMIS physical function CAT (PROMIS PF CAT), and (2) PROMIS PF CAT would not demonstrate ceiling effects. Cohort study (diagnosis); Level of evidence, 3. Sixty-one patients with glenohumeral osteoarthritis were included. Each patient completed the American Shoulder and Elbow Surgeons (ASES) assessment form, Marx Shoulder Activity Scale, Short Form-36 physical function scale (SF-36 PF), EuroQol 5 Dimensions (EQ-5D) questionnaire, Western Ontario Osteoarthritis Shoulder (WOOS) index, PROMIS PF CAT, and the PROMIS UE. Correlation was defined as high (>0.7), moderate (0.4-0.6), or weak (0.2-0.3). Significant floor and ceiling effects were present if more than 15% of individuals scored the lowest or highest possible total score on any PRO. The PROMIS PF demonstrated excellent correlation with the SF-36 PF (r = 0.81, P ceiling or floor effects observed. The mean number of items administered by the PROMIS PRO was 4. These data suggest that for a patient population with operative shoulder osteoarthritis, PROMIS UE and PROMIS PF CAT may be valid alternative PROs. Additionally, PROMIS PF CAT offers a decreased question burden with no ceiling effects.

  11. Epidemiology of brucellosis among cattle in Korea from 2001 to 2011.

    Science.gov (United States)

    Yoon, Hachung; Moon, Oun-Kyong; Lee, Soo-Han; Lee, Won-Chang; Her, Moon; Jeong, Wooseog; Jung, Suk-Chan; Kim, Do-Soon

    2014-12-01

    In the present study, the outbreak patterns of bovine brucellosis in Korea from 2000 to 2011 were analyzed to understand the epidemiological evolution of this disease in the country. A total of 85,521 brucella reactor animals were identified during 14,215 outbreaks over the 12-year study period. The number of bovine brucellosis cases increased after 2003 and peaked in 2006 before decreasing thereafter. The majority of the bovine brucellosis cases were Korean native cattle, Han Woo. The numbers of human brucellosis cases and cattle outbreaks increased and decreased in the same pattern. The correlation coefficient for human and bovine cases per year was 0.96 (95% confidence interval = 0.86 ˜ 0.99; p brucellosis appeared to be affected by the intensity of eradication programs that mainly involved a test- and-slaughter policy. Findings from the present study were based on freely available statistics from web pages maintained by government agencies. This unlimited access to information demonstrates the usefulness of government statistics for continually monitoring the health of animal populations.

  12. SIMULATION OF COOLING TOWER AND INFLUENCE OF AERODYNAMIC ELEMENTS ON ITS WORK UNDER CONDITIONS OF WIND

    Directory of Open Access Journals (Sweden)

    K. V. Dobrego

    2014-01-01

    Full Text Available Modern Cooling Towers (CT may utilize different aerodynamic elements (deflectors, windbreak walls etc. aimed to improvement of its heat performance especially at the windy conditions. In this paper the effect of flow rotation in overshower zone of CT and windbreak walls on a capacity of tower evaporating unit in the windy condition is studied numerically. Geometry of the model corresponds to real Woo-Jin Power station, China. Analogy of heat and mass transfer was used that allowed to consider aerodynamic of one-dimension flow and carried out detailed 3D calculations applying modern PC. Heat transfer coefficient of irrigator and its hydrodynamic resistance were established according to experimental data on total air rate in cooling tower. Numerical model is tested and verified with experimental data.Nonlinear dependence of CT thermal performance on wind velocity is demonstrated with the minimum (critical wind velocity at ucr ~ 8 m/s for simulated system. Application of windbreak walls does not change the value of the critical wind velocity, but may improves performance of cooling unit at moderate and strong wind conditions. Simultaneous usage of windbreak walls and overshower deflectors may increase efficiency up to 20–30 % for the deflectors angle a = 60o. Simulation let one analyze aerodynamic patterns, induced inside cooling tower and homogeneity of velocities’ field in irrigator’s area.Presented results may be helpful for the CT aerodynamic design optimization, particularly, for perspective hybrid type CTs.

  13. Probabilistic seismic hazard assessment of Italy using kernel estimation methods

    Science.gov (United States)

    Zuccolo, Elisa; Corigliano, Mirko; Lai, Carlo G.

    2013-07-01

    A representation of seismic hazard is proposed for Italy based on the zone-free approach developed by Woo (BSSA 86(2):353-362, 1996a), which is based on a kernel estimation method governed by concepts of fractal geometry and self-organized seismicity, not requiring the definition of seismogenic zoning. The purpose is to assess the influence of seismogenic zoning on the results obtained for the probabilistic seismic hazard analysis (PSHA) of Italy using the standard Cornell's method. The hazard has been estimated for outcropping rock site conditions in terms of maps and uniform hazard spectra for a selected site, with 10 % probability of exceedance in 50 years. Both spectral acceleration and spectral displacement have been considered as ground motion parameters. Differences in the results of PSHA between the two methods are compared and discussed. The analysis shows that, in areas such as Italy, characterized by a reliable earthquake catalog and in which faults are generally not easily identifiable, a zone-free approach can be considered a valuable tool to address epistemic uncertainty within a logic tree framework.

  14. A Comparative study of hyperon equations of state in supernova simulations

    CERN Document Server

    Char, Prasanta; Bandyopadhyay, Debades

    2015-01-01

    A comparative study of the $\\Lambda$ hyperon equations of state of Banik, Hempel and Banyopadhyay (BHB) \\citep{bhb} and \\citet{shen11} (denoted as HShen $\\Lambda$) for core collapse supernova (CCSN) simulations is carried out in this work. The dynamical evolution of a protoneutron star (PNS) into a black hole is investigated in core collapse supernova simulations in the general relativistic one dimensional code using the BHB$\\Lambda \\phi$ and HShen $\\Lambda$ equation of state (EoS) tables and different progenitor models from Woosley and Heger \\citep{Woos}. Radial profiles of the mass fractions of baryons, the density as well as the temperature in the PNS at different moments in time, are compared for both EoS tables. The behaviour of the central density of the PNS with time is demonstrated for those two $\\Lambda$ hyperon EoS tables and compared with their corresponding nuclear EoS tables. It is observed that the black hole formation time is higher in the BHB$\\Lambda \\phi$ case than in the HShen $\\Lambda$ EoS ...

  15. Exploring the link between depression and accelerated cellular aging: telomeres hold the key

    Directory of Open Access Journals (Sweden)

    Yu R

    2015-12-01

    Full Text Available Ruby Yu, Jean Woo Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, SAR, China Abstract: Accumulating evidence suggests that telomeres may be a marker for biological aging and telomere length may be affected by multifactorial influences, including cumulative exposure to depression. Associations with telomere length have been reported for major depressive disorder, lifetime duration of depression, higher depression severity, and history of depression. The exact underling mechanisms for these associations have yet to be fully elucidated; however, oxidative stress, chronic inflammation, dysregulated hypothalamus-pituitary-adrenal axis, and altered cortisol levels may be important biochemical mediators. These mediators could also be influenced by psychological stress, unhealthy lifestyle behaviors, or other potential factors, such as childhood abuse, post-traumatic stress disorder, and anxiety that are commonly associated with depression. As such, stress reduction and lifestyle interventions that may affect the telomere maintenance system should be considered for individuals with depression.Keywords: depression, telomere length, biomarkers, cellular ageing

  16. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1985. Part 4 (Burnside Construction Company - Colton Equipment Co).

    Science.gov (United States)

    1985-01-01

    woo CO 0-C 0-cc 00 Q m 0 0 "-4’ t4 co C’) ə( m4 4 " 2 oO-4 0 O CO U 0 CO 3 xO C X CO-E N 03 0a 4 UC4 w 0 ac a-o w D0 0 an 00 ChICO cpnI to 2 .U. 0 0...C - 00 0 0 0 00 0 0 0 0 0 0 < N N N < 00.0L lOLA ~0 0 C) 0 0 ’ I w I 0)I .44 N 0 0 . *~~~~0 0 IV ’ C ’C )0N ’N’ In 0OO 4 I r MWWW OOWW-4 (DO w OO ow CW...0 N, NNV ON C4N r, 0 -mr- LAO Coj (D m 0 lOLA 0 0 0 0 0 0 N -- 0 0 0 0 N, 0 *n 𔃺 LAI N1 Co LANL - -4 -4- -4 --" -4 -4 -4 I ~1 4 C(o 000000 .4 1 oDN

  17. UNRAVELING THE FUNCTIONS OF THE MACROALGAL MICROBIOME

    Directory of Open Access Journals (Sweden)

    Ravindra Pal Singh

    2016-01-01

    Full Text Available Macroalgae are a diverse group of photosynthetic eukaryotic lower organisms and offer indispensable ecosystem services towards sustainable productivity of rocky coastal areas. The earlier studies have mainly focused on elucidation of the roles of the epiphytic bacterial communities in the ecophysiology of the host macroalga. However, mutualistic interactions have become topic of current interest. It is evident from recent studies that a fraction of epiphytic bacterial communities can be categorized as core microbial species, suggesting an obligate association. Epiphytic bacterial communities have also been reported to protect macroalgal surfaces from biofouling microorganisms through production of biologically active metabolites. Because of their intrinsic roles in the host life cycle, the host in turn may provide necessary organic nutrients in order to woo pelagic microbial communities to settle on the host surfaces. However, the precise composition of microbiomes and their functional partnership with hosts are hardly understood. In contrast, the microbial studies associated with human skin and gut and plants have significantly advanced our knowledge on microbiome and their functional interactions with the host. This has led to manipulation of the microbial flora of the human gut and of agricultural plants for improving health and performance. Therefore, it is highly imperative to investigate the functional microbiome that is closely involved in the life cycles of the host macroalgae using high-throughput techniques (metagenomics and metatranscriptomics. The findings from such investigations would help in promoting health and productivity in macroalgal species through regulation of functionally active microbiome.

  18. Alpha List of Prime Contract Awards. Oct 1991 - Sep 1992. FY 1992. (Universal Asphalt Co Inc - ZZYZX)

    Science.gov (United States)

    1993-01-01

    I’ I0-4 I"I NNNNNl-NN N N IN 1-4N N NJ - N N N N N I 0 .I -4 z ZZ Z 2 :.->- 3 2 I 𔃾I0-40 ’I 02 C24 4 N N < < U.1 Q 000) 144 0 0 យto 000 on If.. -4...0- 1 020(N) to𔃺 OD)N0000 00 4.. 04 0, E4 0. M c24 ) " 4t40 >- >0- >-4 N-(JO-4---.4-4 >-0-4 0 0 0-4- 4-CJN O O44 JOf.1>-4 It I M OD - 44i w f IMC>-4 t...400 0 000DO- CLSI - it .- 1I440I0 WOO 00t o Y:I (Y)~ 00I ɘI 0O Ol In =I (00- it .40.0.0.0 ." 0 ITO CV0 Il n -0 00 C(D C14 20 n ~ 1- D I c)0l 1 In

  19. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 21 (VU Color Inc-Zymed Inc)

    Science.gov (United States)

    1990-01-01

    oIn In 1--. in -4 to( IC) In r,. r’- U- c 4 0) INi 41 , ’’) m’ 4’) C24 0000 N" In M’ - C’) m’ 00 00 -4 1 M -4N iI 4-2) 0000 Do 00 0 0 0 0 0 0 0 0 UN0 IM...2 I.- 2 $-- -So IO 44~ 0t 03 0F- -4 0 H IIt4 I-H TIO C24 z 2 cc 2 2 2 r- 24 ON E 0 m 0 t-o 0 1-1 0 43 a o I N 110Q 0 0Q 0 u 0 0 - -1 - -41-1 t- 4...C> in N I Mm It LLA oo Woo-.1 zoo 0c)o)-j oo 0) CY) -.1 (7) 0) C) 0) -1 CY) -i cn oo a (71 at III I M IN It q L) < < cc < < W to 0 < m N :: ClsI 0

  20. Hearing mouth shapes: Sound symbolism and the reverse McGurk effect.

    Science.gov (United States)

    Spence, Charles; Deroy, Ophelia

    2012-01-01

    In their recent article, Sweeny, Guzman-Martinez, Ortega, Grabowecky, and Suzuki (2012) demonstrate that heard speech sounds modulate the perceived shape of briefly presented visual stimuli. Ovals, whose aspect ratio (relating width to height) varied on a trial-by-trial basis, were rated as looking wider when a /woo/ sound was presented, and as taller when a /wee/ sound was presented instead. On the one hand, these findings add to a growing body of evidence demonstrating that audiovisual correspondences can have perceptual (as well as decisional) effects. On the other hand, they prompt a question concerning their origin. Although the currently popular view is that crossmodal correspondences are based on the internalization of the natural multisensory statistics of the environment (see Spence, 2011), these new results suggest instead that certain correspondences may actually be based on the sensorimotor responses associated with human vocalizations. As such, the findings of Sweeny et al. help to breathe new life into Sapir's (1929) once-popular "embodied" explanation of sound symbolism. Furthermore, they pose a challenge for those psychologists wanting to determine which among a number of plausible accounts best explains the available data on crossmodal correspondences.

  1. Development of Graphical Pole-Zero, Root-Locus, Bode, Nyquist, and Nichols Responses Using the OPTSYSX Program.

    Science.gov (United States)

    1984-09-01

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  2. Overground Excess Sound Attenuation (ESA). Volume 1. Experimental Study for Flat Grassy Terrains.

    Science.gov (United States)

    1987-06-01

    I.OOiO WON hit- WOO ioft hiftf IdYS 50N EMfN hiuN sol we 2 1W I W, N W,. "-. N. . I.. N .. 1- . ... i-* . N$- . N. N. bI ID I I .4N . 2.4 2.4. V05 VS5 td ...Cf 0 N ; 0 w ICO vt 4 - .4 . 0 C 1 N u0 0 0 act 0 0- ’A %D b 0 to 91 - I 0 -NY N Na a u . vMh - 0 o vf 0 u in C v IO I .4W . W .. W W - W I I W : II R... tD .. 11) 1 w 68.. 1 6, U5 IA wA IA IA ha 0 0" W-" . .4 0 PP PS a-I 68 680 W* 0ll’ a a I in 4 4 z r. W 4 16 4 4! 9 N I. 12i I N.~5V UWS 0 a4 haN hIVIS

  3. The Subtitling of Indigenous Values in the Film Seediq Bale

    Directory of Open Access Journals (Sweden)

    Tzu-yi Elaine Lee

    2016-02-01

    Full Text Available The movie Seediq Bale, directed by Wei Te-Sheng and produced by John Woo, is a Taiwanese historical drama epic film based on the Wushe Incident in 1930. The story depicts the Wushe Incident, which happened in central Taiwan while it was under Japanese rule. Mona Rudao, a then chief of Seediq indigenous village Mahebu, led warriors against Japanese authorities due to the long-term colonial oppression. In response, the Japanese mounted a relentless counter-attack, killing over three hundred Seediq people. Often compared by the media in Taiwan to the films Braveheart and The Last of the Mohicans, the film, released in 2011, is so far the most expensive production in Taiwan cinema history. Different language registers are present in the movie, including Mandarin, Japanese, and the Seediq language; this can be a great challenge for the translator when translating the subtitles into English. Nonetheless, it is believed that ideologies can be manifested in language use. So, the study attempts to disclose the translator¡¦s hidden indigenous ideologies in the English subtitles s/he provided. Moreover, as subtitling translation involves a multiplicity of verbal and non-verbal semiotic modes, those visual and audio elements could also contribute to the final product of subtitle translations. Hence, the study, in addition to the translator¡¦s indigenous ideologies and handling of ethnic issues in translation, also looks at how the translator worked with semiotic modes in designing the subtitles for the target context.

  4. Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites

    KAUST Repository

    Woo, Yong

    2015-07-15

    The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular parasites of humans and animals with immense socio-economic and health impacts. We sequenced nuclear genomes of Chromera velia and Vitrella brassicaformis, free-living non-parasitic photosynthetic algae closely related to apicomplexans. Proteins from key metabolic pathways and from the endomembrane trafficking systems associated with a free-living lifestyle have been progressively and non-randomly lost during adaptation to parasitism. The free-living ancestor contained a broad repertoire of genes many of which were repurposed for parasitic processes, such as extracellular proteins, components of a motility apparatus, and DNA- and RNA-binding protein families. Based on transcriptome analyses across 36 environmental conditions, Chromera orthologs of apicomplexan invasion-related motility genes were co-regulated with genes encoding the flagellar apparatus, supporting the functional contribution of flagella to the evolution of invasion machinery. This study provides insights into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga. © Woo et al.

  5. Strategies for changing negative public attitudes toward organ donation in the People's Republic of China

    Directory of Open Access Journals (Sweden)

    Shumin X

    2013-12-01

    Full Text Available Xie Shumin,1 Stephanie Mu-Lian Woo,2 Zhang Lei3 1Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital of Central South University, Changsha, People's Republic of China; 2Harvard University, Cambridge, Massachusetts, USA; 3Department of Thoracic Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People's Republic of China Abstract: In recent decades, the demand for organ transplantation has risen rapidly worldwide, due to an increased incidence of vital organ failure. However, the scarcity of organs appropriate for transplantation has led to an organ shortage crisis. This article retrospectively reviews strategies to change negative public attitudes toward organ donation in the People's Republic of China. We strongly believe that efforts to publicize knowledge of organ donation, promote family discussions, train medical staff and students, establish incentive systems, and implement regulatory oversight may combat unfavorable Chinese public opinion toward organ donation and transplantation, thus potentially increasing the organ donation rate in the People's Republic of China. Keywords: influencing factors, attitudes, organ transplantation, organ failure

  6. DoD Statistical Report on the Military Retirement System. Fiscal Year 1983.

    Science.gov (United States)

    1983-01-01

    02) eo O0 r- 0, C) --4 m~ -* Lo N- .- 4 uA C’) LA-4m - CO M’ .- 4 C’) CV) CC LA LA LA Ul LL) U O~Ln tD - ON C.J C\\)r- r-- r CJ 4.0C\\j~ --I N -)C)O...ico *c c c w N 0KK u K K 0 La 0~ -- 4 z ="O o;= 0lto N_ -n-m-a -. La I., w o 42P20 ap w K 4 -a - - -4- - N w w o = m = ov o a c m o m m o P 40...o coca cocoa 00000 co000 =0 woO .4000C miomfl 0.92 000o cocoa 0 00 0:00. 9 0 2 0 0 U, .1..0 .4. C 4 02 #0 CD tD j. 0. 40 nW I !n ZO9Z 0B2& 4NII

  7. A Framework for Interaction and Cognitive Engagement in Connectivist Learning Contexts

    Directory of Open Access Journals (Sweden)

    Zhijun Wang

    2014-04-01

    Full Text Available Interaction has always been highly valued in education, especially in distance education (Moore, 1989; Anderson, 2003; Chen, 2004a; Woo & Reeves, 2007; Wang, 2013; Conrad, in press. It has been associated with motivation (Mahle, 2011; Wen-chi, et al., 2011, persistence (Tello, 2007; Joo, Lim, & Kim, 2011, deep learning (Offir, et al., 2008 and other components of effective learning. With the development of interactive technologies, and related connectivism learning theories (Siemens, 2005a; Downes, 2005, interaction theory has expanded to include interactions not only with human actors, but also with machines and digital artifacts. This paper explores the characteristics and principles of connectivist learning in an increasingly open and connected age. A theory building methodology is used to create a new theoretical model which we hope can be used by researchers and practitioners to examine and support multiple types of effective educational interactions. Inspired by the hierarchical model for instructional interaction (HMII (Chen, 2004b in distance learning, a framework for interaction and cognitive engagement in connectivist learning contexts has been constructed. Based on cognitive engagement theories, the interaction of connectivist learning is divided into four levels: operation interaction, wayfinding interaction, sensemaking interaction, and innovation interaction. Connectivist learning is thus a networking and recursive process of these four levels of interaction.

  8. Development of a chitosan based double layer-coated tablet as a platform for colon-specific drug delivery

    Directory of Open Access Journals (Sweden)

    Kim MS

    2016-12-01

    Full Text Available Min Soo Kim,1,* Dong Woo Yeom,1,* Sung Rae Kim,1 Ho Yub Yoon,1 Chang Hyun Kim,1 Ho Yong Son,1 Jin Han Kim,1 Sangkil Lee,2 Young Wook Choi1 1College of Pharmacy, Chung-Ang University, Seoul, 2College of Pharmacy, Keimyung University, Daegu, South Korea *These authors contributed equally to this work Abstract: A double layer-coated colon-specific drug delivery system (DL-CDDS was developed, which consisted of chitosan (CTN based polymeric subcoating of the core tablet containing citric acid for microclimate acidification, followed by an enteric coating. The polymeric composition ratio of Eudragit E100 and ethyl cellulose and amount of subcoating were optimized using a two-level factorial design method. Drug-release characteristics in terms of dissolution efficiency and controlled-release duration were evaluated in various dissolution media, such as simulated colonic fluid in the presence or absence of CTNase. Microflora activation and a stepwise mechanism for drug release were postulated. Consequently, the optimized DL-CDDS showed drug release in a controlled manner by inhibiting drug release in the stomach and intestine, but releasing the drug gradually in the colon (approximately 40% at 10 hours and 92% at 24 hours in CTNase-supplemented simulated colonic fluid, indicating its feasibility as a novel platform for CDD. Keywords: chitosan, colon-specific delivery, acidification, microflora, factorial design, controlled release

  9. Biomimetics: forecasting the future of science, engineering, and medicine

    Directory of Open Access Journals (Sweden)

    Hwang J

    2015-09-01

    Full Text Available Jangsun Hwang,1 Yoon Jeong,1,2 Jeong Min Park,3 Kwan Hong Lee,1,2,4 Jong Wook Hong,1,2 Jonghoon Choi1,2 1Department of Bionano Technology, Graduate School, Hanyang University, Seoul, 2Department of Bionano Engineering, Hanyang University ERICA, Ansan, Korea; 3Department of Biomedical Engineering, Boston University, 4OpenView Venture Partners, Boston, MA, USA Abstract: Biomimetics is the study of nature and natural phenomena to understand the principles of underlying mechanisms, to obtain ideas from nature, and to apply concepts that may benefit science, engineering, and medicine. Examples of biomimetic studies include fluid-drag reduction swimsuits inspired by the structure of shark’s skin, velcro fasteners modeled on burrs, shape of airplanes developed from the look of birds, and stable building structures copied from the backbone of turban shells. In this article, we focus on the current research topics in biomimetics and discuss the potential of biomimetics in science, engineering, and medicine. Our report proposes to become a blueprint for accomplishments that can stem from biomimetics in the next 5 years as well as providing insight into their unseen limitations. Keywords: biomimicry, tissue engineering, biomaterials, nature, nanotechnology, nanomedicine

  10. Adaptive memory: the survival scenario enhances item-specific processing relative to a moving scenario.

    Science.gov (United States)

    Burns, Daniel J; Hart, Joshua; Griffith, Samantha E; Burns, Amy D

    2013-01-01

    Nairne, Thompson, and Pandeirada (2007) found that retention of words rated for their relevance to survival is superior to that of words encoded under numerous other deep processing conditions. They suggested that our memory systems might have evolved to confer an advantage for survival-relevant information. Burns, Burns, and Hwang (2011) suggested a two-process explanation of the proximate mechanisms responsible for the survival advantage. Whereas most control tasks encourage only one type of processing, the survival task encourages both item-specific and relational processing. They found that when control tasks encouraged both types of processing, the survival processing advantage was eliminated. However, none of their control conditions included non-survival scenarios (e.g., moving, vacation, etc.), so it is not clear how this two-process explanation would explain the survival advantage when scenarios are used as control conditions. The present experiments replicated the finding that the survival scenario improves recall relative to a moving scenario in both a between-lists and within-list design and also provided evidence that this difference was accompanied by an item-specific processing difference, not a difference in relational processing. The implications of these results for several existing accounts of the survival processing effect are discussed.

  11. The discovery of processing stages: Extension of Sternberg's method.

    Science.gov (United States)

    Anderson, John R; Zhang, Qiong; Borst, Jelmer P; Walsh, Matthew M

    2016-10-01

    We introduce a method for measuring the number and durations of processing stages from the electroencephalographic signal and apply it to the study of associative recognition. Using an extension of past research that combines multivariate pattern analysis with hidden semi-Markov models, the approach identifies on a trial-by-trial basis where brief sinusoidal peaks (called bumps) are added to the ongoing electroencephalographic signal. We propose that these bumps mark the onset of critical cognitive stages in processing. The results of the analysis can be used to guide the development of detailed process models. Applied to the associative recognition task, the hidden semi-Markov models multivariate pattern analysis method indicates that the effects of associative strength and probe type are localized to a memory retrieval stage and a decision stage. This is in line with a previously developed the adaptive control of thought-rational process model, called ACT-R, of the task. As a test of the generalization of our method we also apply it to a data set on the Sternberg working memory task collected by Jacobs, Hwang, Curran, and Kahana (2006). The analysis generalizes robustly, and localizes the typical set size effect in a late comparison/decision stage. In addition to providing information about the number and durations of stages in associative recognition, our analysis sheds light on the event-related potential components implicated in the study of recognition memory. (PsycINFO Database Record

  12. Light scattering resonances in arbitrarily shaped one-dimensional reentrant surfaces

    Science.gov (United States)

    Negrete-Regagnon, Pedro; Hernandez-Walls, Rafael; Ruiz-Cortes, Victor

    2000-09-01

    Multiple scattering and shape-related effects are an active and important field of research in the area of diffraction and scattering of electromagnetic waves by rough surfaces. Most of the rigorous numerical techniques for dealing with this problem were limited to the treatment of single-valued surfaces. We have extended the formulation of Mendoza- Suarez and Mendez (1997) for dealing with multi-valued profile functions in order to study the scattering of reentrant surfaces or cavities in both, the near and far-field. We have evaluated the near-field in circular cavities with narrow entrances, as well as in the case of clusters of rods or cylinders. Resonant frequencies are clearly identified for these structures. We have also found that our model could be useful to predict wave-induced oscillations in harbors of arbitrary geometry. This comes form the fact that the mathematical formulation of the problem of light scattering by cavities (in the case of p polarization) is similar to the one employed in the case of harbors of arbitrary shape, when a water wave arrives at its entrance (Hwang and Tuck, 1970; Lee, 1971). The results obtained with our model are in close agreement with previously reported theories and experimental data.

  13. Nanoscale bacteriophage biosensors beyond phage display

    Directory of Open Access Journals (Sweden)

    Lee JW

    2013-10-01

    Full Text Available Jong-Wook Lee,1 Jangwon Song,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea; 2Department of Biomedical Engineering, University of Science and Technology, Seoul, Korea Abstract: Bacteriophages are traditionally used for the development of phage display technology. Recently, their nanosized dimensions and ease with which genetic modifications can be made to their structure and function have put them in the spotlight towards their use in a variety of biosensors. In particular, the expression of any protein or peptide on the extraluminal surface of bacteriophages is possible by genetically engineering the genome. In addition, the relatively short replication time of bacteriophages offers researchers the ability to generate mass quantities of any given bacteriophage-based biosensor. Coupled with the emergence of various biomarkers in the clinic as a means to determine pathophysiological states, the development of current and novel technologies for their detection and quantification is imperative. In this review, we categorize bacteriophages by their morphology into M13-based filamentous bacteriophages and T4- or T7-based icosahedral bacteriophages, and examine how such advantages are utilized across a variety of biosensors. In essence, we take a comprehensive approach towards recent trends in bacteriophage-based biosensor applications and discuss their outlook with regards to the field of biotechnology. Keywords: biosensing, M13 bacteriophage, T4 bacteriophage, bacterial detection, Escherichia coli, SPR sensor

  14. Initial conformation of kinesin's neck linker

    CERN Document Server

    Geng, Yi-Zhao; Liu, Shu-Xia; Yan, Shiwei

    2013-01-01

    How ATP binding initiates the docking process of kinesin's neck linker is a key question in understanding kinesin mechanism. It is believed that the formation of an extra turn structure by the first three amino acids of neck linker (LYS325, THR326, ILE327 in 2KIN) is crucial for initiating the docking process. But the initial conformation of neck linker (specially the three amino acids of the extra turn) and the neck linker docking initiation mechanism remain unclear. By using molecular dynamics method, we investigate the initial conformation of kinesin's neck linker in the docking process. We find that, in the initial state of NL docking process, NL still has interactions with {\\beta}0 and forms a conformation similar to the "cover-neck bundle" structure proposed by Hwang et al. [Structure 2008, 16(1): 62-71]. From this initial structure, the docking of the "cover-neck bundle" structure can be achieved. The motor head provides a forward force on the initial cover-neck bundle structure through ATP-induced rot...

  15. A Visual Cryptography Based Watermark Technology for Individual and Group Images

    Directory of Open Access Journals (Sweden)

    Azzam Sleit

    2007-04-01

    Full Text Available The ease by which digital information can be duplicated and distributed has led to the need for effective copyright protection tools. Various techniques including watermarking have been introduced in attempt to address these growing concerns. Most watermarking algorithms call for a piece of information to be hidden directly in media content, in such a way that it is imperceptible to a human observer, but detectable by a computer. This paper presents an improved cryptographic watermark method based on Hwang and Naor-Shamir [1, 2] approaches. The technique does not require that the watermark pattern to be embedded in to the original digital image. Verification information is generated and used to validate the ownership of the image or a group of images. The watermark pattern can be any bitmap image. Experimental results show that the proposed method can recover the watermark pattern from the marked image (or group of images even if major changes are reflected on the original digital image or any member of the image group such as rotation, scaling and distortion.

  16. Behavioral adjustments of African herbivores to predation risk by lions: spatiotemporal variations influence habitat use.

    Science.gov (United States)

    Valeix, M; Loveridge, A J; Chamaillé-Jammes, S; Davidson, Z; Murindagomo, F; Fritz, H; Macdonald, D W

    2009-01-01

    Predators may influence their prey populations not only through direct lethal effects, but also through indirect behavioral changes. Here, we combined spatiotemporal fine-scale data from GPS radio collars on lions with habitat use information on 11 African herbivores in Hwange National Park (Zimbabwe) to test whether the risk of predation by lions influenced the distribution of herbivores in the landscape. Effects of long-term risk of predation (likelihood of lion presence calculated over four months) and short-term risk of predation (actual presence of lions in the vicinity in the preceding 24 hours) were contrasted. The long-term risk of predation by lions appeared to influence the distributions of all browsers across the landscape, but not of grazers. This result strongly suggests that browsers and grazers, which face different ecological constraints, are influenced at different spatial and temporal scales in the variation of the risk of predation by lions. The results also show that all herbivores tend to use more open habitats preferentially when lions are in their vicinity, probably an effective anti-predator behavior against such an ambush predator. Behaviorally induced effects of lions may therefore contribute significantly to structuring African herbivore communities, and hence possibly their effects on savanna ecosystems.

  17. Influence of prey dispersion on territory and group size of African lions: a test of the resource dispersion hypothesis.

    Science.gov (United States)

    Valeix, Marion; Loveridge, Andrew J; MacDonald, David W

    2012-11-01

    Empirical tests of the resource dispersion hypothesis (RDH), a theory to explain group living based on resource heterogeneity, have been complicated by the fact that resource patch dispersion and richness have proved difficult to define and measure in natural systems. Here, we studied the ecology of African lions Panthera leo in Hwange National Park, Zimbabwe, where waterholes are prey hotspots, and where dispersion of water sources and abundance of prey at these water sources are quantifiable. We combined a 10-year data set from GPS-collared lions for which information of group composition was available concurrently with data for herbivore abundance at waterholes. The distance between two neighboring waterholes was a strong determinant of lion home range size, which provides strong support for the RDH prediction that territory size increases as resource patches are more dispersed in the landscape. The mean number of herbivore herds using a waterhole, a good proxy of patch richness, determined the maximum lion group biomass an area can support. This finding suggests that patch richness sets a maximum ceiling on lion group size. This study demonstrates that landscape ecology is a major driver of ranging behavior and suggests that aspects of resource dispersion limit group sizes.

  18. The importance of HIV prevention messaging for orphaned youth in Zimbabwe.

    Science.gov (United States)

    Haney, Erica; Singh, Kavita

    2012-01-01

    The AIDS epidemic has contributed to a drastic increase in the number of orphans in Zimbabwe. Female adolescent orphans are particularly in jeopardy of contracting HIV due to disadvantages including extreme poverty, low education, and the absent of parental oversight which can lead to higher risk-taking sexual behaviors. By understanding where girls receive education about HIV and who they rely on for information, organizations can effectively modify existing programs to better target this at-risk population. For this study a household survey was conducted which included 216 orphans and 324 non-orphans (n=540), aged 12-17 years, in the resource-poor setting of Hwange District, Zimbabwe. The aims of this article were to examine the differences between orphans and non-orphans in HIV prevention message exposure, level of motivation for learning about HIV, and communication with caregivers about safe sex. The household survey revealed that younger orphans, aged 12-15 years, were more motivated to learn about HIV and had greater HIV messaging exposure in school than non-orphans. These exposure and differences in the levels of motivation between groups dissipated at older ages. Our research also discovered less caregiver communication among orphans than non-orphans. Our findings suggest that HIV programs targeting orphans need to do a better job at keeping older orphans interested in HIV prevention at a time when it matters most. Furthermore, intervention strategies that provide caregiver support are instrumental in effectively delivering prevention messages to girls at home.

  19. 关于Steiner比猜想%A Report on the Steiner Ratio Conjecture

    Institute of Scientific and Technical Information of China (English)

    越民义

    2000-01-01

    The paper consists of an introduction and two sections. In the introduction we give a short historical review about this problem and, incidentally, point out some mistakes in the paper by Du and Hwang [4], and assert that their proof is wrong. By this way, we hope to be able to justify our motive of writing this paper. Section 2 gives some new and simple proofs for the cases n =3, 4 and 5. In section 3, the general case is discussed in details, and a proof is given to the truth of the Steiner Ratio Conjecture.%本文所讨论的是Steiner比猜想.全文共分两部分:第一部分包括历史回顾和对n=3,4,5三种情况对该猜想的正确性给出了简单的证明;第二部分则对于一般的n给出了一个证明.

  20. Mapping the entangled ontology of science teachers’ lived experience

    DEFF Research Database (Denmark)

    Daugbjerg, Peer Schrøder; de Freitas, E.; Valero, Paola

    2015-01-01

    In this paper we investigate how the bodily activity of teaching, along with the embodied aspect of lived experience, relates to science teachers’ ways of dealing with bodies as living organisms which are both the subject matter as well as the site or vehicle of learning. More precisely, the foll......In this paper we investigate how the bodily activity of teaching, along with the embodied aspect of lived experience, relates to science teachers’ ways of dealing with bodies as living organisms which are both the subject matter as well as the site or vehicle of learning. More precisely......, the following questions are pursued: (1) In what ways do primary science teachers refer to the lived and living body in teaching and learning? (2) In what ways do primary science teachers tap into past experiences in which the body figured prominently in order to teach students about living organisms? We draw...... on the relational ontology and intra-action of Karen Barad (J Women Cult Soc 28(3): 801, 2003) as she argues for a “relational ontology” that sees a relation as a dynamic flowing entanglement of a matter and meaning. We combine this with the materialist phenomenological studies of embodiment by SungWon Hwang...

  1. Flow noise predictions of a submerged cylinder under turbulent boundary layer excitations

    Science.gov (United States)

    Wu, Kuangcheng; Vlahopoulos, Nickolas

    2002-05-01

    The unsteady fluctuated pressure underneath turbulent boundary layers (TBL) is one of major noise sources in moving vehicles. Recently, discretized TBL forcing functions have been applied to planar structures in air [Y. F. Hwang and S. A. Hambric, Noise-Con, 2000; M. Allen and N. Vlahopoulos, Computers and Structures, 2000; M. Allen and N. Vlahopoulos, Finite Elements in Analysis and Design, 2001; M. Allen, R. Sbragio, and N. Vlahopoulos, AIAA J. 2001]. This paper discusses prediction of the flow-induced radiated noise and surface responses of a submerged hemisphere-capped cylindrical shell (L/D=11). The FEM/IFEM (infinite finite element method) approach is used to calculate structural acoustic transfer functions and to accurately account for the fluid loading effects. The effect on TBL due to the curvature of a cylinder is captured by utilizing the potential flow-boundary layer theory to determine key boundary layer parameters. Predictions of the surface intensity and far field responses are developed through stochastic analysis due to the natural of the TBL excitations. A MATLAB script is generated to determine the power spectral density of the responses. [Work supported by ONR Code 334.

  2. Secure and robust steganographic algorithm for binary images

    Science.gov (United States)

    Agaian, Sos S.; Cherukuri, Ravindranath

    2006-05-01

    In recent years, active research has mainly concentrated on authenticating a signature; tracking a document in a digital library, and tamper detection of a scanned document or secured communication using binary images. Binary image steganographical systems provide a solution for the above discussed issues. The two color constraint of the image limits the extension of various LSB embedding techniques to the binary case. In this paper, we present a new data hiding system for binary images and scanned documents. The system initially identifies embeddable blocks and enforces specific block statistics to hide sensitive information. The distribution of the flippable pixels in these blocks is highly uneven over the image. A variable block embedding threshold is employed for capitalizing on this uneven distribution of pixels. In addition, we also present a measure to find the best the cover given a specific file of sensitive information. The simulation was performed over 50 various binary images such the scanned documents, cartoons, threshold color images. Simulation results shows that 1) The amount of data embedded is comparatively higher than the existing algorithms (such as K.H. Hwang et.al [5], J. Chen et.al [10], M.Y.Wu et.al [9]). 2) The visual distortion in cover image is minimal when compared with the existing algorithms (such as J. Chen[10], M.Y.Wu et.al [9]) will be presented.

  3. Collisions of Rydberg Atoms with Charged Particles

    Science.gov (United States)

    MacAdam, Keith B.

    2000-10-01

    The long range of Coulomb interactions, together with the large size, long radiative lifetimes and high state densities of highly excited Rydberg atoms, results in inelastic collision cross sections of prodigious size -- often large enough to outweigh small number densities in astrophysica and cool laboratory plasmas -- and in other unusual features. This talk will provide: (a) a brief survey of the significant features of collisions between electron or positive ions and state-selected Rydberg atoms and of recent experiments( O. Makarov and K.B. MacAdam, Phys. Rev. A 60), 2131-8 (1999); and K.B. MacAdam, J.C. Day and D.M. Homan, Comm. At. Mol. Phys./Comm. Mod. Phys. 1(2), Part D, 57-73 (1999). to investigate them; (b) an introduction to some of the special techniques that have been developed(J.L. Horn, D.M. Homan, C.S. Hwang, W.L. Fuqua III and K.B. MacAdam, Rev. Sci. Instrum. 69), 4086-93 (1998). for preparation, manipulation and detection of Rydberg atoms; and (c) a glimpse at new directions in Rydberg atom collision research.

  4. Linking Arctic amplification and local feedbacks

    Science.gov (United States)

    Balcerak, Ernie

    2011-11-01

    Climate simulations show that as the Earth warms, the Arctic warms more than the average global warming. However, models differ on how much more the Arctic warms, and although scientists have proposed a variety of mechanisms to explain the Arctic warming amplification, there is no consensus on the main reasons for it. To shed light on this issue, Hwang et al. investigated the relationship between Arctic amplification and poleward energy transport and local Arctic feedbacks, such as changes in cloud cover or ice loss, across a group of models. The researchers noted that differences in atmospheric energy transport did not explain the ranges of polar amplification; rather, models with more amplification showed less energy transport into high latitudes. The authors found that decreasing energy transport is due to a coupled relationship between Arctic amplification and energy transport: Arctic amplification reduces the equator-to-pole temperature gradient, which strongly decreases energy transport. They suggest that this coupled relationship should be taken into account in studies of Arctic amplification. (Geophysical Research Letters, doi:10.1029/2011GL048546, 2011)

  5. Talking with members of the globalization of materials R&D study

    Science.gov (United States)

    Byko, Maureen

    2006-03-01

    The Committee on Globalization of Materials Research and Development was appointed by the U.S. National Research Council in December 2003. Its charge: to assess the status and impacts of the globalization of materials R&D. The 12-member committee, which included representatives from both U.S. and international academia and industry, published its findings in August 2005 in the form of a report Globalization of Materials R&D —Time for a National Strategy. To gain some perspective on the report's findings, JOM spoke with representatives of the committee, retired from Alcoa; Gordon Geiger, director of the engineering management program and professor of industrial engineering at the University of Arizona; Jennie Hwang, president of H-Technologies Group in Cleveland. Ohio: and Michael Jaffe, director, Medical Device Concept Laboratory of New Jersey Institute of Technology and associate research professor at Rutgers University in Newark, New Jersey. See the sidebar for a listing of the committee's recommendations. The interviews were conducted by e-mail and telephone; respondents chose which questions to answer.

  6. Optical and X-ray studies of MOCVD-grown InGaN epilayers with low indium concentration

    Science.gov (United States)

    Park, Gil; Hwang, Seon-Ju; Shee, Sang-Kee; Sugahara, Tomoya; Lam, Jack; Gainer, Gordon; Song, Jin-Joo; Sakai, S.

    2001-03-01

    Optical and X-ray studies of MOCVD-grown InGaN epilayers with low indium concentration G. H. Park, S. J. Hwang, S. K. Shee, T. Sugahara, J. B. Lam, G. H. Gainer and J. J. Song, Center for Laser and Photonics Research and Department of Physics, Oklahoma State University, Stillwater, OK 74078, USA; S. Sakai, Electrical and Electronic Department, University of Tokushima, Tokushima, Japan. In_xGa_1-xN epilayers with low indium concentration (x < 5%) were grown by low pressure metalorganic chemical vapor deposition on (0001) sapphire. These samples were characterized by optical techniques and high-resolution X-ray diffraction. Photoluminescence (PL) and stimulated emission (SE) were measured. The PL intensity of the InGaN epilayers is much higher than that of GaN, even for very small indium concentrations. The PL peaks show the S-shaped temperature dependence, and the stimulated emission threshold is also temperature dependent. The PL and SE also vary greatly with indium concentration. These observations indicate that the way indium incorporates into GaN varies with In concentration. The structural characteristics will be discussed in light of their possible relation to the optical characteristics. This work is supported by ONR, BMDO, and AFOSR.

  7. Surface Segregation and Bulk Thermodynamics in Blends of Long-Branched and Linear Chains

    Science.gov (United States)

    Martter, T. D.; Foster, M. D.; Xu, S.; Yoo, T.; Quirk, R. P.; Ohno, K.; Haddleton, D. M.; Hawker, C.; Majkrzak, C.; Butler, P.

    2001-03-01

    We have investigated the effect of regular long chain branching on bulk thermodynamics and surface segregation in blends of linear and branched polymers. Polystyrene and low vinyl content polybutadiene polymerized anionically have both been studied. The nonlocal thermodynamic interaction between the chains in the bulk can be characterized by a segment-segment interaction parameter, chi, measured using Small Angle Neutron Scattering. While chi is found to increase monotonically with the number of arms in the star for PS blends, this is not true for PB blends. In the case of the PB blends, isotopic effects play a more important role in determining the segregation behavior than in the case of the PS blends. Some experiments have also been performed to probe the effect of core chemistry on the bulk and surface behavior. Changing the type of long-branched component from star-branched to comb-branched, while the number of arms is kept constant, impacts both the bulk interaction and surface segregation. Acknowledgements: Collaborators were G. Lizzaraga, J. Hwang, C.C. Greenberg, S. Corona-Galvan, and E. Cloutet (Institute of Polymer Science at The University of Akron) and J.D. Demaree (Army Research Lab, AMSRL-WM-ME, APG, MD 21005).

  8. Upper limit to magnetism in LaAIO3/SrTiO3 heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Fitzsimmons, Michael R [Los Alamos National Laboratory

    2012-02-27

    In 2004 Ohtomo and Hwang reported unusually high conductivity in LaAl03 and SrTi03 bilayer samples. Since then, metallic conduction, superconductivity, magnetism, and coexistence of superconductivity and ferromagnetism have been attributed to LaAl03/SrTi03 interfaces. Very recently, two studies have reported large magnetic moments attributed to interfaces from measurement techniques that are unable to distinguish between interfacial and bulk magnetism. Consequently, it is imperative to perform magnetic measurements that by being intrinsically sensitive to interface magnetism are impervious to experimental artifacts suffered by bulk measurements. Using polarized neutron reflectometry we measured the neutron spin dependent reflectivity from four LaAl03/SrTi03 superlattices. Our results indicate the upper limit for the magnetization averaged over the lateral dimensions of the sample induced by an 11 T magnetic field at 1.7 K is less than 2 G. SQUID magnetometry of the neutron superlattice samples sporadically finds an enhanced moment (consistent with past reports), possibly due to experimental artifacts. These observations set important restrictions on theories which imply a strongly enhanced magnetism at the interface between LaAI03 and SrTi03.

  9. Interface fractal construction in Ni⧸KBr⧸Ni system

    Science.gov (United States)

    Shang, Chang He; Li, Heng De

    1994-04-01

    Non-equilibrium aggregation behavior on a surface has attracted increasing attention among researchers. It was found that at the early stage of film formation particles could coagulate into the form of diffusion-limited aggregation (DLA) on a free substrate surface. By using scanning tunnelling microscopy, Hwang, Schroder, Gunther and Behm [Phys. Rev. Lett. 67 (1991) 3279] recently showed that on the clean Ru surface, Au atoms grew into irregular islands of a fractal character as well. Similar monolayer growth was also found on a constrained surface, i.e., the interface between two lattice planes. In this paper, we report on the cluster aggregation behavior between two metallic layers. Samples were prepared by alternatively depositing pure constituent materials onto freshly cleaved NaCl single crystals in a high vacuum. Transmission electron microscopy was used to characterize the surface construction. It was found that KBr dendritic islands on the constrained surface also had a fractal geometry. The growth dynamics could be modified by adding interface impurities. Our experiment showed that Al addition onto the constrained surface could accelerate the growth process and degraded the fractal dimension. Detailed results will be presented, and some possible mechanisms will also be discussed.

  10. Mobile Authoring of Open Educational Resources as Reusable Learning Objects

    Directory of Open Access Journals (Sweden)

    Dr Kinshuk

    2013-06-01

    Full Text Available E-learning technologies have allowed authoring and playback of standardized reusable learning objects (RLO for several years. Effective mobile learning requires similar functionality at both design time and runtime. Mobile devices can play RLO using applications like SMILE, mobile access to a learning management system (LMS, or other systems which deploy content to mobile learners (Castillo & Ayala, 2008; Chu, Hwang, & Tseng, 2010; Hsu & Chen, 2010; Nakabayashi, 2009; Zualkernan, Nikkhah, & Al-Sabah, 2009. However, implementations which author content in a mobile context do not typically permit reuse across multiple contexts due to a lack of standardization. Standards based (IMS and SCORM authoring implementations exist for non-mobile platforms (Gonzalez-Barbone & Anido-Rifon, 2008; Griffiths, Beauvoir, Liber, & Barrett-Baxendale, 2009; Téllez, 2010; Yang, Chiu, Tsai, & Wu, 2004. However, this paradigm precludes capturing learning where and when it occurs. Consequently, RLO authored for e-learning lack learner generated content, especially with timely, relevant, and location aware examples.

  11. Penyusunan Tata Kelola Teknologi Informasi Bagi Pemerintah Daerah Menggunakan Framework Cobit 5 (Studi Kasus: Kabupaten Cilacap

    Directory of Open Access Journals (Sweden)

    Annas Wahyu Purwanto

    2013-12-01

    ABSTRACT The failure of the e -government implementation in Indonesia according to Junseok Hwang and Irfan Syamsudin, who were doing research in South Sulawesi, are from the government, not from the people.  Meanwhile in Cilacap District,  Long Term Development Plan for the period 2005-2025 mentioned that e-government in Cilacap already implemented but not optimal yet. Cole methodology used in this study consists of 4 (four stages: problem identification , intervention , evaluation and reflection and learning. Conduct a gap analysis and risk analysis to determine the priorities that need to be carried out in Cilacap Kabupaten. To pursue a level of capability gaps that occur and mitigate the risks that may arise, Cilacap necessary to establish an organizational structure of information technology (IT, convey the purpose and management direction to stakeholders, understanding the direction of government development, develop a vision of the IT architecture governance, maintain the availability of the IT staff, identify IT personnel key, maintain the skills and competency of IT personnel, evaluate the performance achievement of IT personnel and also planning  and mapping of IT human resources .

  12. The crystal structure of an HSL-homolog EstE5 complex with PMSF reveals a unique configuration that inhibits the nucleophile Ser144 in catalytic triads.

    Science.gov (United States)

    Nam, Ki Hyun; Kim, Soo-Jin; Priyadarshi, Amit; Kim, Hyun Sook; Hwang, Kwang Yeon

    2009-11-13

    The esterase/lipase family (EC 3.1.1.3/EC 3.1.1.1) represents a diverse group of hydrolases that catalyze the cleavage of ester bonds and are widely distributed in animals, plants and microorganisms. Among these enzymes, hormone-sensitive lipases, play a critical role in the regulation of rodent fat cell lipolysis and are regarded as adipose tissue-specific enzymes. Recently, we reported the structural and biological characterization of EstE5 from the metagenome library [K.H. Nam, M.Y. Kim, S.J. Kim, A. Priyadarshi, W.H. Lee, K.Y. Hwang, Structural and functional analysis of a novel EstE5 belonging to the subfamily of hormone-sensitive lipase, Biochem. Biophys. Res. Commun. 379 (2009) 553-556]. The structure of this protein revealed that it belongs to the HSL-family. Here, we report the inhibition of the activity of the HSL-homolog EstE5 protein as determined by the use of esterase/lipase inhibitors. Our results revealed that the EstE5 protein is significantly inhibited by PMSF. In addition, this is the first study to identify the crystal structures of EstE5-PMSF at 2.4 and 2.5A among the HSL-homolog structures. This structural configuration is similar to that adopted when serine proteases are inhibited by PMSF. The results presented here provide valuable information regarding the properties of the HSL-family.

  13. Growth behavior and properties of nano Pb quantum islands on Si(111) surfaces at low temperatures

    Science.gov (United States)

    Tsong, Tien T.

    2004-03-01

    Quantum effects can affect the dynamic properties of surface atoms and the growth behavior of nanometer size islands. Using scanning tunneling microscopy (STM), we have studied: 1) Dynamics of atoms and silicon magic clusters on clean Si(111)-7x7 surfaces. 2) How the electronic property affects the growth behavior of Pb ultra-thin quantum-islands on the Si(111) surface. We find the low temperature growth of Pb quantum-islands on the Si(111)-7x7 surface is affected by the electronic standing wave states formed in the normal direction of these islands. The scaling behavior in the growth of these multilayer flat-top quantum islands can be described by a scaling theory of growth of single layer 2D islands with a minor modification. 3) Observed the vertical Friedel oscillation of the electronic Morie patterns formed at the Pb-Si interface and found the decay of the amplitude to follow the inverse square of the distance to the interface. 4) Observed the dynamics of a structure phase transition of monolayer quasi two dimensional Pb islands and its size effect. These and other recent interesting observations of ours will be presented. Coworkers: C-S Chang, I-S Hwang, W-B Su, M-S Ho, W-B Jian, and S-H Chang etc. Work supported by NSC of Taiwan and Academia Sinica (Taiwan).

  14. Performance Analysis of IMS Network: the Proposal of new Algorithms for S-CSCF Assignment

    Directory of Open Access Journals (Sweden)

    Lubos Nagy

    2013-01-01

    Full Text Available This article is focused on the proposal of three load balancing methods which can be used for a selection of S-CSCF (Serving-Call Session Control Server server in IP Multimedia Subsystem (IMS during the registration procedures of subscribers. All presented methods are implemented and evaluated for various inter-arrival and service times in the mathematical model based on queueing theory. In this article, two methods based on performance parameters (such as utilizations, etc. and one method based on number of registered subscribers to each of available S-CSCF server are described. The main advantage of third method is that all related information is obtained from traffic analysis through I-CSCF (Interrogating-CSCF node. Also, the designed methods are compared with other selection algorithms presented in previous research works by others researchers (Hwang et col., Cho et col. or Tirana et col.. The article shows that the implemented methods can optimize the service latency of whole IMS network.

  15. A glimpse into the interactions of cells in a microenvironment: the modulation of T cells by mesenchymal stem cells

    Directory of Open Access Journals (Sweden)

    Choi J

    2014-05-01

    Full Text Available Jonghoon Choi,1,2 Mintai P Hwang,3 Jong-Wook Lee,3 Kwan Hyi Lee3,41Institute of Research Strategy and Development (IRSD, Seoul, Republic of Korea; 2Department of Bionano Engineering, Hanyang University, Ansan, Republic of Korea; 3Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea; 4Department of Biomedical Engineering, University of Science and Technology, Seoul, Republic of KoreaAbstract: Mesenchymal stem cells (MSCs have been thought to hold potential as a mode of therapy for immuno-related pathologies, particularly for autoimmune diseases. Despite their potential, the interaction between MSCs and T cells, key players in the pathophysiology of autoimmune diseases, is not yet well understood, thereby preventing further clinical progress. A major obstacle is the highly heterogeneous nature of MSCs in vitro. Unfortunately, bulk assays do not provide information with regard to cell–cell contributions that may play a critical role in the overall cellular response. To address these issues, we investigated the interaction between smaller subsets of MSCs and CD4 T cells in a microwell array. We demonstrate that MSCs appear capable of modulating the T cell proliferation rate in response to persistent cell–cell interactions, and we anticipate the use of our microwell array in the classification of subpopulations within MSCs, ultimately leading to specific therapeutic interventions.Keywords: mesenchymal stem cell, T cell, microwell array

  16. New extended standard model, dark matters and relativity theory

    Science.gov (United States)

    Hwang, Jae-Kwang

    2016-03-01

    Three-dimensional quantized space model is newly introduced as the extended standard model. Four three-dimensional quantized spaces with total 12 dimensions are used to explain the universes including ours. Electric (EC), lepton (LC) and color (CC) charges are defined to be the charges of the x1x2x3, x4x5x6 and x7x8x9 warped spaces, respectively. Then, the lepton is the xi(EC) - xj(LC) correlated state which makes 3x3 = 9 leptons and the quark is the xi(EC) - xj(LC) - xk(CC) correlated state which makes 3x3x3 = 27 quarks. The new three bastons with the xi(EC) state are proposed as the dark matters seen in the x1x2x3 space, too. The matter universe question, three generations of the leptons and quarks, dark matter and dark energy, hadronization, the big bang, quantum entanglement, quantum mechanics and general relativity are briefly discussed in terms of this new model. The details can be found in the article titled as ``journey into the universe; three-dimensional quantized spaces, elementary particles and quantum mechanics at https://www.researchgate.net/profile/J_Hwang2''.

  17. Repeat microgravity data from Mesilla Valley, New Mexico, 2016-2017

    Science.gov (United States)

    Kennedy, Jeffrey R.; Robertson, Andrew J.; Carruth, Robert; Rinehart, Alex J.

    2017-01-01

    This dataset represents the network-adjusted results of relative- and absolute-gravity surveys in Mesilla and Las Cruces, New Mexico. Relative-gravity surveys were carried out using a Zero Length Spring, Inc. relative-gravity meter. The effect of solid Earth tides and ocean loading were removed from the data. Instrument drift was removed by evaluating gravity change during repeated measurements at one or more base stations. Absolute-gravity surveys were carried out using a Micro-g LaCoste, Inc. A-10 absolute-gravity meter. Vertical gradients between the different measuring heights of the absolute- and relative-gravity meters were measured using a relative-gravity meter and tripod, and used to correlate the measurements between the two instruments. Relative-gravity differences and absolute-gravity data were combined using a least-squares network adjustment, as implemented in the software Gravnet (Hwang, C., Wang, C., Lee, L., 2002. Adjustment of relative gravity measurements using weighted and datum-free constraints. Comput. Geosci. 28, 1005–1015). Additional information about the network adjustment is provided under Data Quality. Data pre- and post-processing were carried out using GSadjust (https://github.com/jkennedy-usgs/GSadjust).Data are provided in shapefile and tabular (csv) format. The shapefile contains one entry per station per date. The csv file contains one row per station, with multiple columns for gravity, and gravity change converted to water-storage change.

  18. Bicultural competence, acculturative family distancing, and future depression in Latino/a college students: a moderated mediation model.

    Science.gov (United States)

    Carrera, Stephanie G; Wei, Meifen

    2014-07-01

    In his acculturative family distancing (AFD) theory, Hwang (2006b) argued that acculturation gaps among parents and youth may lead to psychological and emotional distancing. AFD includes 2 dimensions: incongruent cultural values and breakdowns in communication. This study examined whether bicultural competence (BC) served as a mediator and moderator for the relationship between AFD and depression using structural equation modeling. Two hundred and forty-one Latino/a college students attending predominantly White, midwestern universities completed an online survey at 2 time points. For mediation, results indicated that BC at Time 2 (T2) mediated the relationship between AFD at Time 1 (T1) and depression at T2 above and beyond the effects of depression, acculturation, and enculturation at T1. A bootstrap method estimated the significance of the indirect effect. Moreover, 16% of the variance in BC at T2 was explained by acculturation, enculturation, and AFD at T1; 30% of the variance in depression at T2 was explained by BC at T2 and depression at T1. Post hoc analyses of the AFD and BC dimensions suggested that (a) positive attitudes toward both groups, communication ability, and social groundedness were significant mediators for the incongruent cultural values-depression link and (b) communication ability and social groundedness were significant mediators for the communication breakdown-depression link. For moderation, the AFD × BC interaction did not significantly predict depression at T2. Limitations, future research directions, and counseling implications are discussed.

  19. Evidence of Broken Reciprocity in Cholesteric Liquid Crystals

    Science.gov (United States)

    Venkataraman, Nithya; Moreira, Michele; Taheri, Bahman; Palffy-Muhoray, Peter

    2007-03-01

    Reciprocity of scattering of a plane incident wave is predicated on bounded scattering media with symmetric and linear permittivity, conductivity and permeability. In chiral media, such as cholesteric liquid crystals, the dielectric tensor is asymmetric due the presence of odd powers of the wave vector resulting from nonlocality and broken inversion symmetry. Evidence of non-reciprocity has been found in optically active crystals by Bennet [1] and in stacks of cholesteric and nematic liquid crystal cells [2]. Here we present transmittance and reflectance data for cholesteric cells with different pitches having overlapping but distinct reflection bands. We relate our results to simple analytic descriptions of the materials properties and of propagating modes and assess them in light of the requirements for reciprocity. 1. P.J. Bennett, S. Dhanjal, Yu. P. Svirko and N. I. Zheludev, Opt. Lett. 21, 1955 (1996) 2. J. Hwang; M.H. Song; B. Park; S. Nishimura; T. Toyooka; J.W. Wu; Y. Takanishi; K. Ishikawa; H. Takezoe, Nat. Mat. 4, 383 (2005).

  20. Evidence of Broken Reciprocity in Chiral Liquid Crystals

    Science.gov (United States)

    Moreira, Michele; Venkataraman, Nithya; Taheri, Bahman; Palffy-Muhoray, Peter

    2008-03-01

    Reciprocity in light scattering is predicated on bounded scattering media with symmetric and linear permittivity, conductivity and permeability. Due to their anisotropy and chirality, cholesteric liquid crystal form periodic dielectric structures. If the periodicity is comparable to the wavelength of light, these phases are self-assembled photonic band gap structures. There appear in the permittivity odd powers of the wave vector resulting from nonlocality and broken inversion symmetry. Evidence of non-reciprocity has been found in optically active crystals by Bennett [1] and in stacks of cholesteric and nematic liquid crystal cells by Takezoe [2]. We present experimental data showing broken reciprocity in transmittance and reflectance in cholesteric cells with different pitches having overlapping but distinct reflection bands. We explain our results in terms of simple analytic descriptions of material properties and propagating modes. [1] P.J. Bennett, S. Dhanjal, Yu. P. Svirko and N. I. Zheludev, Opt. Lett. 21, 1955 (1996) [2] J. Hwang; M.H. Song; B. Park; S. Nishimura; T. Toyooka; J.W. Wu; Y. Takanishi; K. Ishikawa; H. Takezoe, Nat. Mat. 4, 383 (2005).

  1. The Visible Spectrum of Titanium Dioxide

    Science.gov (United States)

    Zhuang, Xiujuan; Steimle, Timothy C.; Nagarajann, Ramya; Maier, John P.

    2010-06-01

    Bulk TiO2 is a widely used photo-activated catalytic material, yet poorly understood. Much of the motivation for studies of molecular TiO2 is the observation that there is a smooth correlation of the molecular electronic states to the band gap of the bulk. The field-free energy levels of the ground state of the monomer have been fully characterized by microwave spectroscopy. Here we report on the visible spectrum in the region between 18200 cm-1 to 18750 cm-1 of a cold molecular beam sample of TiO2 using laser induced fluorescence detection and mass-selected REMPI. Bands at 18240 cm-1, 18411 cm-1 and 18470 cm-1 were recorded at a resolution of 40 MHz and rotationally analyzed. The dispersed fluorescence of 18411 cm-1 and 18470 cm-1 bands were analyzed to produce a set of vibrational parameters for the ground state. The optical Stark spectra of the 18411 cm-1 and 18470 cm-1 bands were recorded and analyzed to determine permanent electric dipole moments and compared with the results for the band at 18655 cm-1. H.J. Zhai and L.-S. Wang JACS 129 3022, 2007. S.Brunken; H. S. P. Muller; K.M. Menten; M. C. McCarthy and P. Thaddeus Ap. J. 676 1367, 2008. H.Wang; T.C. Steimle; C. Apetrei and J.P. Maier PCCP 11 2649, 2008.

  2. NRF2011-EDU001-EL001 EduLab Project Scaling-up Reflections on Using Open Source Physics

    CERN Document Server

    Wee, Loo Kang; Lye, Sze Yee

    2014-01-01

    eduLab (MOE, 2012b) is a key programme under the third MasterPlan for ICT in Education (mp3) where teachers with good ideas for an ICT-enhanced lesson or curriculum (learning with computer models through inquiry, example PhET (PhET, 2011) can come together to collaborate. eduLab aims to support teachers to develop, prototype and test-bed their lesson ideas (journey in 2012-2014) while ensuring that the results, in the form of complete lesson packages (see http://edulab.moe.edu.sg/edulab-programmes/existing-projects third project), are scalable across schools to benefit the wider teaching community. Our models and lessons are downloadable here http://weelookang.blogspot.sg/2013/03/moe-excel-fest-2013-scaling.html We have collaborated with namely Professor Francisco Esquembre, Professor Fu-Kwun Hwang and Wolfgang Christian and created Open Source Computer Models on the topic of 1 Dimensional Collision (Loo Kang Wee, 2012b), Falling Magnet in Coil, Ripple Tank (Duffy, 2010; G. H. Goh et al., 2012; Ong, Ng, Goh, ...

  3. Food Safety Program in Asian Countries.

    Science.gov (United States)

    Yamaguchi, Ryuji; Hwang, Lucy Sun

    2015-01-01

    By using the ILSI network in Asia, we are holding a session focused on food safety programs in several Asian areas. In view of the external environment, it is expected to impact the global food system in the near future, including the rapid increase in food demand and in public health services due to population growth, as well as the threats to biosecurity and food safety due to the rapid globalization of the food trade. Facilitating effective information sharing holds promise for the activation of the food industry. At this session, Prof. Hwang shares the current situation of Food Safety and Sanitation Regulations in Taiwan. Dr. Liu provides a talk on the role of risk assessment in food regulatory control focused on aluminum-containing food additives in China. After the JECFA evaluation of aluminum-containing food additives in 2011, each country has carried out risk assessment based on dietary intake surveys. Ms. Chan reports on the activities of a working group on Food Standards Harmonization in ASEAN. She also explains that the ILSI Southeast Asia Region has actively supported the various ASEAN Working Groups in utilizing science to harmonize food standards. Prof. Park provides current research activities in Korea focused on the effect of climate change on food safety. Climate change is generally seen as having a negative impact on food security, particularly in developing countries. We use these four presentations as a springboard to vigorous discussion on issues related to Food Safety in Asia.

  4. Estimation of CANDU spent fuel disposal canister lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Kook, Dong Hak; Lee, Min Soo; Hwang, Yong Soo; Choi, Heui Joo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-05-15

    Active nuclear energy utilization causes significant spent fuel accumulation problem. The cumulative amount of spent fuel is about 10,083 ton as of Dec. 2008, and is expected to increase up to 19,000 ton by 2020. Of those, CANDU spent fuels account for more than 60% of the total amounts. CANDU spent fuels had been stored in dry concrete silos since 1991 and during the past 15 years, 300 silos were constructed and {approx}3,200 ton of spent fuels are stored now. Another dry storage facility MACSTOR /KN-400 will store new-coming CANDU spent fuels from 2009. But, after intermediate storage ends, all CANDU spent fuels have to be disposed within multi-layer metallic canister which is composed of cast iron inside and copper outside. Canister lifetime estimation, therefore, is very important for the final disposal safety analysis. The most significant factor of lifetime is copper corrosion, and Y. S. Hwang developed a corrosion model in order to predict the general corrosion effect on copper canister lifetime during the final disposal period. This research applied his model to KURT1 where many disposal researches are being performed actively and the results shows safe margin of the copper canister for the very long-term disposal.

  5. Data Mining for Vortices on the Earth's Magnetosphere

    Science.gov (United States)

    Collado-Vega, Y. M.; Kalb, V.; Sibeck, D. G.

    2016-12-01

    This research validates a method to detect and characterize vortices based on velocity from simulation data. The current algorithm involves systematically searching the 3-dimensional velocity fields to identify critical points, points where the magnitude of the velocity vector field vanishes, making these points candidates for vortex centers. We utilize the Community Coordinated Modeling Center (CCMC) run on request capability to create a series of model runs initialized from the conditions observed by the Cluster mission in the Hwang et al., 2011 analysis of Kelvin Helmholtz vortices observed during southward IMF. The fast data characterization and vortex detection will permit the scientist to focus in on different magnetosphere locations for further investigation in large data sets. This not only saves time to scientist, but also diminishes the potential for missing features of interest. We also analyze further the properties of the vortices found including the velocity changes within their motion across the magnetosheath, and the potential of our tool to characterize transient features (e.g. Flux Transfer Event (FTEs)) with vortical internal structures.

  6. Electrostatic control of many-body interactions in graphene: Observation of the effects of doping on the saddle-point exciton

    Science.gov (United States)

    Mak, Kin Fai; He, Keliang; Petrone, Nick; Hone, Jim; Shan, Jie; Heinz, Tony

    2012-02-01

    Significant excitonic effects were recently identified in the optical response of graphene through the asymmetric resonance feature at 4.62 eV in the optical conductivity. The peak, which is red-shifted by nearly 600 meV from the predicted band-to-band transition energy,ootnotetextMak et al. Phys. Rev. Lett. 106, 046401, (2011). can be considered as a saddle-point exciton. Here we report a systematic study of this excitonic feature as a function of the doping density, for densities extending up to the metallic regimeootnotetextEfetov & Kim, Phys. Rev. Lett. 105, 256805, (2010). (˜ 10^14 cm-2). With increasing density of either electrons or holes, the excitonic resonance is found to shift to the red and to become more symmetric in form. These experimental features agree very well with a recent ab-initio GW-Bethe-Salpeter calculationootnotetextFelipe H. da Jornada, J. D., Steven G. Louie. Private communications. (2011). and can be understood as a consequence of enhanced ``metallic'' screening of the graphene dielectric function.ootnotetextHwang, E. H. & Das Sarma, S. Phys. Rev. B 75, 205418 In addition, analysis of the width of the excitonic peak provides information on the quasiparticle lifetime. Mechanisms for the inferred rapid quasiparticle decoherence will be discussed.

  7. Correction factors for the INER-improved free-air ionization chambers calculated with the Monte Carlo method.

    Science.gov (United States)

    Lin, Uei-Tyng; Chu, Chien-Hau

    2006-05-01

    Monte Carlo method was used to simulate the correction factors for electron loss and scattered photons for two improved cylindrical free-air ionization chambers (FACs) constructed at the Institute of Nuclear Energy Research (INER, Taiwan). The method is based on weighting correction factors for mono-energetic photons with X-ray spectra. The newly obtained correction factors for the medium-energy free-air chamber were compared with the current values, which were based on a least-squares fit to experimental data published in the NBS Handbook 64 [Wyckoff, H.O., Attix, F.H., 1969. Design of free-air ionization chambers. National Bureau Standards Handbook, No. 64. US Government Printing Office, Washington, DC, pp. 1-16; Chen, W.L., Su, S.H., Su, L.L., Hwang, W.S., 1999. Improved free-air ionization chamber for the measurement of X-rays. Metrologia 36, 19-24]. The comparison results showed the agreement between the Monte Carlo method and experimental data is within 0.22%. In addition, mono-energetic correction factors for the low-energy free-air chamber were calculated. Average correction factors were then derived for measured and theoretical X-ray spectra at 30-50 kVp. Although the measured and calculated spectra differ slightly, the resulting differences in the derived correction factors are less than 0.02%.

  8. Laser-driven Beat-Wave Current Drive in Dense Plasmas with Demo on CTIX

    Science.gov (United States)

    Liu, Fei; Horton, Robert; Hwang, David; Zhu, Ben; Evans, Russell; Hong, Sean; Hsu, Scott

    2010-11-01

    The ability to remotely generate plasma current in dense plasmas hanging freely in vacuum in voluminous amount without obstruction to diagnostics will greatly enhance our ability to study the physics of high energy density plasmas in strong magnetic fields. Plasma current can be generated through nonlinear beat-wave process by launching two intense electromagnetic waves into unmagnetized plasma. Beat-wave acceleration of electrons has been demonstrated in a low-density plasma using microwaves [1]. The proposed PLX experimental facility presently under construction at Los Alamos offers the opportunity to test the method at a density level scalable to the study of HED plasmas. For PLX beat-wave experiments, CO2 lasers will be used as pump waves due to their high power and tunability. For a typical PLX density ne=10^17cm-3, two CO2 lasers can be separately tuned to 9P(28) and 10P(20) to match the 2.84THz plasma frequency. The beat-wave demo experiment will be conducted on CTIX. The laser arrangement is being converted to two independent single lasers. Frequency-tuning methods, optics focusing system and diagnostics system will be discussed. The laser measurements and results of synchronization of two lasers will be presented, and scaling to PLX experiments will be given. [1] Rogers, J. H. and Hwang, D. Q., PRL. v68 p3877 (1992).

  9. Cryptanalysis and Performance Evaluation of Enhanced Threshold Proxy Signature Scheme Based on RSA for Known Signers

    Directory of Open Access Journals (Sweden)

    Raman Kumar

    2013-01-01

    Full Text Available In these days there are plenty of signature schemes such as the threshold proxy signature scheme (Kumar and Verma 2010. The network is a shared medium so that the weakness security attacks such as eavesdropping, replay attack, and modification attack. Thus, we have to establish a common key for encrypting/decrypting our communications over an insecure network. In this scheme, a threshold proxy signature scheme based on RSA, any or more proxy signers can cooperatively generate a proxy signature while or fewer of them cannot do it. The threshold proxy signature scheme uses the RSA cryptosystem to generate the private and the public key of the signers (Rivest et al., 1978. Comparison is done on the basis of time complexity, space complexity, and communication overhead. We compare the performance of four schemes (Hwang et al. (2003, Kuo and Chen (2005, Yong-Jun et al. (2007, and Li et al. (2007, with the performance of a scheme that has been proposed earlier by the authors of this paper. In the proposed scheme, both the combiner and the secret share holder can verify the correctness of the information that they are receiving from each other. Therefore, the enhanced threshold proxy signature scheme is secure and efficient against notorious conspiracy attacks.

  10. Security Analysis and Performance Evaluation of Enhanced Threshold Proxy Signature Scheme Based on RSA for Known Signers

    Directory of Open Access Journals (Sweden)

    Raman Kumar

    2012-08-01

    Full Text Available An efficient threshold signature scheme solves the difficulties of the receiver to proof the approval of the document from the sender as well as detecting if the file has been altered by illegitimate parties. In these days there are plenty of signature schemes such as (t,n threshold proxy signature scheme. The network is a shared medium so that the weakness security attacks such as eavesdropping, replay attack and modification attack. Thus, we have to establish a common key for encrypting/decrypting our communications over an insecure network. In this scheme, a (t,n threshold proxy signature scheme based on RSA, any t or more proxy signers can cooperatively generate a proxy signature while t-1 or fewer of them can’t do it. The threshold proxy signature scheme uses the RSA cryptosystem to generate the private and the public key of the signers. Comparison is done on the basis of time complexity, space complexity and communication overhead. We compare the performance of four schemes: Hwang et al., Wen et al., Geng et al. and Fengying et al. with the performance of a scheme that has been proposed by the authors of this article earlier. In the proposed scheme, both the combiner and the secret share holder can verify the correctness of the information that they are receiving from each other. Therefore, the enhanced threshold proxy signature scheme is secure and efficient against notorious conspiracy attacks.

  11. Cinema, paesaggio e turismo “andaluzadas”: la Spagna andalusizzata, patrimonio retroproiettato / Cinema, landscape and “andaluzadas” tourism: the Andalusian Spain, a rear-projected heritage

    Directory of Open Access Journals (Sweden)

    Rocío Liáñez Andrades

    2016-05-01

    Full Text Available La Spagna si è proiettata cinematograficamente al turismo internazionale attraverso la sua immagine più pittoresca e singolare: l’Andalusia. In questo modo, anche nelle produzioni realizzate in altre regioni spagnole (Galizia, Madrid, Castiglia-La Mancia, Catalogna compare lo stereotipo più vincolato alla sua immagine romantica secolare.Questa sineddoche identitaria dell'essere spagnolo è stata agevolata dalle istituzioni turistiche, coscienti della loro capacità di attrazione sul turista straniero, e anche dagli stessi spagnoli, che hanno presentato una visione satirica di questo fenomeno di furto di identità nazionale.Per documentare la nostra ipotesi è stata eseguita l’analisi cinematografica (semiotica e di contenuto di una lista di film proposti, produzioni spagnole e coproduzioni con partecipazione o supporto nazionale. Si tratta di produzioni che non esitano a immergersi negli stereotipi più radicati dell’immaginario andaluso, riconoscendoli e riconoscendosi in questi. Ne emerge in questo modo sia la vocazione etnografica e folkloristica delle produzioni destinate alla proiezione internazionale, sia l’impoverimento della suddetta immagine per l’utente nazionale.Quest’articolo percorre le produzioni sopra citate ed espone l’eventuale collegamento di questi “film pasticcio” con film di recente uscita, come Mission: Impossible 2 (John Woo, 2000, Knight and day (James Mangold, 2010 o Zindagi na milegi dobara (Zoya Akhtar, 2012. Spain presented itself in films in order to promote international tourism through its picturesque and unique image: Andalusia. In this way, including in productions that took place in other regions (Galicia, Madrid, Castile-La Mancha, Catalonia, the basic and most cliché Andalusian appears in its romantic and secular image. This identifying synecdoche of “Spanish Identity” was seen as favored by touristic institutions. Aware of their power of attraction over foreign touristic consumers

  12. Cinema, paesaggio e turismo “andaluzadas”: la Spagna andalusizzata, patrimonio retroproiettato

    Directory of Open Access Journals (Sweden)

    Rocío Liáñez Andrades

    2016-05-01

    Full Text Available La Spagna si è proiettata cinematograficamente al turismo internazionale attraverso la sua immagine più pittoresca e singolare: l’Andalusia. In questo modo, anche nelle produzioni realizzate in altre regioni spagnole (Galizia, Madrid, Castiglia-La Mancia, Catalogna compare lo stereotipo più vincolato alla sua immagine romantica secolare.Questa sineddoche identitaria dell'essere spagnolo è stata agevolata dalle istituzioni turistiche, coscienti della loro capacità di attrazione sul turista straniero, e anche dagli stessi spagnoli, che hanno presentato una visione satirica di questo fenomeno di furto di identità nazionale.Per documentare la nostra ipotesi è stata eseguita l’analisi cinematografica (semiotica e di contenuto di una lista di film proposti, produzioni spagnole e coproduzioni con partecipazione o supporto nazionale. Si tratta di produzioni che non esitano a immergersi negli stereotipi più radicati dell’immaginario andaluso, riconoscendoli e riconoscendosi in questi. Ne emerge in questo modo sia la vocazione etnografica e folkloristica delle produzioni destinate alla proiezione internazionale, sia l’impoverimento della suddetta immagine per l’utente nazionale.Quest’articolo percorre le produzioni sopra citate ed espone l’eventuale collegamento di questi “film pasticcio” con film di recente uscita, come Mission: Impossible 2 (John Woo, 2000, Knight and day (James Mangold, 2010 o Zindagi na milegi dobara (Zoya Akhtar, 2012. Spain presented itself in films in order to promote international tourism through its picturesque and unique image: Andalusia. In this way, including in productions that took place in other regions (Galicia, Madrid, Castile-La Mancha, Catalonia, the basic and most cliché Andalusian appears in its romantic and secular image. This identifying synecdoche of “Spanish Identity” was seen as favored by touristic institutions. Aware of their power of attraction over foreign touristic consumers

  13. Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients

    Directory of Open Access Journals (Sweden)

    Park HY

    2015-12-01

    Full Text Available Hye Yun Park,1 Hyun Lee,1 Won-Jung Koh,1 Seonwoo Kim,2 Ina Jeong,3 Hyeon-Kyoung Koo,4 Tae-Hyung Kim,5 Jin Woo Kim,6 Woo Jin Kim,7 Yeon-Mok Oh,8 Don D Sin,9 Seong Yong Lim,10,* Sang-Do Lee8,* On behalf of the KOLD Study Group 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Biostatistics Team, Samsung Biomedical Research Institute, Seoul, Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center, Seoul, Korea; 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea; 5Division of Pulmonary and Critical Care Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Korea; 6Division of Pulmonology, Department of Internal Medicine, Uijeongbu St Mary’s Hospital, Gyunggi-do, Korea; 7Department of Internal Medicine, Kangwon National University, Chuncheon-si, Gangwon-do, Korea; 8Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 9Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada; 10Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea *These authors contributed equally to this work Background: COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS in combination with a long-acting bronchodilator. Recent studies have demonstrated a significant correlation of sputum eosinophilia with blood eosinophils and periostin. We investigated whether high blood eosinophils and plasma periostin were associated

  14. Molecular Dynamics Calculations

    Science.gov (United States)

    1996-01-01

    The development of thermodynamics and statistical mechanics is very important in the history of physics, and it underlines the difficulty in dealing with systems involving many bodies, even if those bodies are identical. Macroscopic systems of atoms typically contain so many particles that it would be virtually impossible to follow the behavior of all of the particles involved. Therefore, the behavior of a complete system can only be described or predicted in statistical ways. Under a grant to the NASA Lewis Research Center, scientists at the Case Western Reserve University have been examining the use of modern computing techniques that may be able to investigate and find the behavior of complete systems that have a large number of particles by tracking each particle individually. This is the study of molecular dynamics. In contrast to Monte Carlo techniques, which incorporate uncertainty from the outset, molecular dynamics calculations are fully deterministic. Although it is still impossible to track, even on high-speed computers, each particle in a system of a trillion trillion particles, it has been found that such systems can be well simulated by calculating the trajectories of a few thousand particles. Modern computers and efficient computing strategies have been used to calculate the behavior of a few physical systems and are now being employed to study important problems such as supersonic flows in the laboratory and in space. In particular, an animated video (available in mpeg format--4.4 MB) was produced by Dr. M.J. Woo, now a National Research Council fellow at Lewis, and the G-VIS laboratory at Lewis. This video shows the behavior of supersonic shocks produced by pistons in enclosed cylinders by following exactly the behavior of thousands of particles. The major assumptions made were that the particles involved were hard spheres and that all collisions with the walls and with other particles were fully elastic. The animated video was voted one of two

  15. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes

    Directory of Open Access Journals (Sweden)

    Cho YY

    2014-11-01

    Full Text Available Yong-Yeon Cho,1 Hyeon-Uk Jeong,1 Jeong-Han Kim,2 Hye Suk Lee1 1College of Pharmacy, The Catholic University of Korea, Bucheon, Korea; 2Department of Agricultural Biotechnology, Seoul National University, Seoul, Korea Abstract: Honokiol, 2-(4-hydroxy-3-prop-2-enyl-phenyl-4-prop-2-enyl-phenol, an active component of Magnolia officinalis and Magnolia grandiflora, exerts various pharmacological activities such as antitumorigenic, antioxidative, anti-inflammatory, neurotrophic, and antithrombotic effects. To investigate whether honokiol acts as a perpetrator in drug interactions, messenger ribonucleic acid (mRNA levels of phase I and II drug-metabolizing enzymes, including cytochrome P450 (CYP, UDP-glucuronosyltransferase (UGT, and sulfotransferase 2A1 (SULT2A1, were analyzed by real-time reverse transcription polymerase chain reaction following 48-hour honokiol exposure in three independent cryopreserved human hepatocyte cultures. Honokiol treatment at the highest concentration tested (50 µM increased the CYP2B6 mRNA level and CYP2B6-catalyzed bupropion hydroxylase activity more than two-fold in three different hepatocyte cultures, indicating that honokiol induces CYP2B6 at higher concentrations. However, honokiol treatment (0.5–50 µM did not significantly alter the mRNA levels of phase I enzymes (CYP1A2, CYP3A4, CYP2C8, CYP2C9, and CYP2C19 or phase II enzymes (UGT1A1, UGT1A4, UGT1A9, UGT2B7, and SULT2A1 in cryopreserved human hepatocyte cultures. CYP1A2-catalyzed phenacetin O-deethylase and CYP3A4-catalyzed midazolam 1'-hydroxylase activities were not affected by 48-hour honokiol treatment in cryopreserved human hepatocytes. These results indicate that honokiol is a weak CYP2B6 inducer and is unlikely to increase the metabolism of concomitant CYP2B6 substrates and cause pharmacokinetic-based drug interactions in humans. Keywords: honokiol, human hepatocytes, drug interactions, cytochrome P450, UDP-glucuronosyltransferases

  16. Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery

    Directory of Open Access Journals (Sweden)

    Song KH

    2015-03-01

    Full Text Available Keon-Hyoung Song,1 Sang-Bum Kim,2 Chang-Koo Shim,2 Suk-Jae Chung,2 Dae-Duk Kim,2 Sang-Ki Rhee,1 Guang J Choi,1 Chul-Hyun Kim,3 Kiyoung Kim4 1Department of Pharmaceutical Engineering, Soonchunhyang University, Asan, Republic of Korea; 2College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea; 3Department of Sports Medicine, 4Department of Medical Biotechnology, Soonchunhyang University, Asan, Republic of Korea Background: The identification of permeation enhancers has gained interest in the development of drug delivery systems. A six-mer peptide, H-FCIGRL-OH (AT1002, is a tight junction modulator with promising permeation-enhancing activity. AT1002 enhances the transport of molecular weight markers or agents with low bioavailability with no cytotoxicity. However, AT1002 is not stable in neutral pH or after incubation under physiological conditions, which is necessary to fully uncover its permeation-enhancing effect. Thus, we increased the stability or mitigated the instability of AT1002 by modifying its terminal amino acids and evaluated its subsequent biological activity.Methods: C-terminal-amidated (FCIGRL-NH2, Pep1 and N-terminal-acetylated (Ac-FCIGRL, Pep2 peptides were analyzed by liquid chromatography–mass spectrometry. We further assessed cytotoxicity on cell monolayers, as well as the permeation-enhancing activity following nasal administration of the paracellular marker mannitol.Results: Pep1 was nontoxic to cell monolayers and showed a relatively low decrease in peak area compared to AT1002. In addition, administration of mannitol with Pep1 resulted in significant increases in the area under the plasma concentration–time curve and peak plasma concentration at 3.63-fold and 2.68-fold, respectively, compared to mannitol alone. In contrast, no increase in mannitol concentration was shown with mannitol/AT1002 or mannitol/Pep2 compared to the control. Thus, Pep1 increased

  17. [Use of comet assay for the risk assessment of oil- and chemical-industry workers].

    Science.gov (United States)

    Megyesi, János; Biró, Anna; Wigmond, László; Major, Jenő; Tompa, Anna

    2014-11-23

    Bevezetés: A comet assay a DNS száltöréseinek kimutatására alkalmas fluoreszcens mikroszkópos módszer. Jelentősége az alacsony sejtszámú mintáknál mutatkozik, képes számokban kifejezni a DNS-károsodást a nem proliferáltatható sejtekben. Célkitűzés: Genotoxikus, illetve oxidatív DNS-károsodásokat mértünk foglalkozásuk során benzollal, policiklusos aromás szénhidrogénekkel, illetve sztirollal exponált csoportokban. Célunk volt annak megvizsgálása, hogy a módszer használható-e genotoxikológiai monitorhatás markereként. Módszer: A comet assay alaplépései mellett az enzimkezelt mintát formamido-pirimidin-DNS glikoláz restrikciós enzimmel kezeljük, ami az oxidatív DNS-károsodás mértékére utal. Eredmények: A kezeletlen (genotoxikus DNS-károsodás) és a kezelt (oxidatív DNS-károsodás) minták esetében emelkedés volt tapasztalható a csóvahosszokat illetően minden csoporton belül a kontrollhoz képest. Következtetések: Megállapítható, hogy a környezeti (munkahelyi) expozíció valószínűsíthető a vizsgált csoportokban. A comet assay kitűnő hatásmarker, illetve kiegészítő módszer lehet egy monitorrendszerben, amelynek adatai tájékoztatást adhatnak a munkahelyeken emelkedett genotoxikus hatások jelenlétéről vagy hiányáról. Orv. Hetil., 2014, 155(47), 1872–1875.

  18. Tautinė reprezentacija Vladimiro Dubeneckio steigiamojo seimo interjere (1924 m.

    Directory of Open Access Journals (Sweden)

    Lina Preišegalavičienė

    2011-06-01

    Full Text Available Rusų kilmės dailininkas, architektas, pedagogas Vladimiras Dubeneckis (1888–1932 gerai žinomas Lietuvoje dėl vertingo architektūrinio palikimo, kurį sukūrė mūsų kraštui gyvendamas ir dirbdamas Kaune 1919–1932 m. Straipsnio tikslas aptarti mažiau žinomą V. Dubeneckio kūrybos pusę – visuomeninių patalpų interjerus. Iki šiol mažai nagrinėta tema leis praplėsti požiūrį į žinomo architekto kūrybą, kartu suteiks papildomos medžiagos Lietuvos interjerų istorijai. Kadangi reprezentatyvumo aspektas interjeruose yra vienas iš svarbesnių konceptualių siekių, tyrimui pasirinktas Steigiamojo Seimo patalpų interjeras (1924 m.. Seimo interjero projekte daugiausia dėmesio buvo skiriama posėdžių salės įrangai ir baldams projektuoti. Straipsnyje nagrinėjama, kaip architekto atkurtos ir kūrybiškai perdirbtos praeities stilių formos bei tautodailės motyvai sąveikauja tarpusavyje, kad būtų išreikšta tautinė reprezentacija. Aptariant Steigiamojo Seimo interjero projektą pastebima tarpukariu oficialiajai reprezentacijai taikytas tautinis stilius, gvildenamos šio stiliaus ištakos interjero dizaine. Straipsnyje keliama hipotezė, kad tautinis stilius buvo visai Europai būdingo XX a. pradžios tarptautinio proceso art nauveau tęsinys, o vėliau – art deco dalis. Kadangi nagrinėjamu laikotarpiu greta tautinės reprezentacijos egzistavo ir kiti reprezentacijos tipai, siekiant juos palyginti straipsnyje paminėti dar keli tarpukario Lietuvos kultūrinės ir visuomeninės paskirties reprezentaciniai interjerai: Ministrų kabinetas ir Vytauto Didžiojo muziejus.Straipsnis lietuvių kalba

  19. Cloning and Analysis of Decay-related Genes of lrpex lacteus%白囊耙齿菌腐朽木材相关cDNA片段的序列克隆与分析

    Institute of Scientific and Technical Information of China (English)

    孟凡娟; 刘欣; 闫绍鹏; 王秋玉

    2011-01-01

    为了解白囊耙齿菌腐朽木材的分子机制,利用基因差异显示技术(Differential display reverse transcriptase,PCRDDRT-PCR)研究了白囊耙齿菌腐朽白桦木材前后基因表达的差异.共分离出5个腐朽后在菌丝体中特异表达的cDNA片段,分别命名为A2、A7、C6、B8和B3.序列同源性比对发现:片段A2、A7和C6分别与编码漆酶(Laccase)、纤维素酶A(Cellulase A)和麦芽糊精磷酸化酶(Maltodextrin phosphorylase)等3个基因具有高度同源性;B8与一个编码响应调节蛋白的基因具有高度同源性.研究结果显示,所筛选的差异表达基因A2、A7和C6等与木材降解有密切关系.%In order to know molecular mechanism of wood decayed by Irpex lacteus, the expression of the decay-related genes of /. Lacteus were analyzed after inoculated with Betula platyphylla Suk wood, by the method of differential display reverse transcriptase PCR (DDRT-PCR). Five special expressed Cdna segments of the mycelium of I. Lacteus were obtained from the decayed wood, which were named as A2, A7, C6, B8 and B3. Among them, A2, A7 and C6 were highly homologous to known genes including laccase, cellulase A and maltodextrin phosphorylase, respectively. B8 was highly homologous to responding regulated protein. This study suggested that A2, A7 and C6 had a close relationship with wood decay. Fig 2, Tab 2, Ref 22

  20. E-Waste and Harm to Vulnerable Populations: A Growing Global Problem

    Science.gov (United States)

    Heacock, Michelle; Kelly, Carol Bain; Asante, Kwadwo Ansong; Birnbaum, Linda S.; Bergman, Åke Lennart; Bruné, Marie-Noel; Buka, Irena; Carpenter, David O.; Chen, Aimin; Huo, Xia; Kamel, Mostafa; Landrigan, Philip J.; Magalini, Federico; Diaz-Barriga, Fernando; Neira, Maria; Omar, Magdy; Pascale, Antonio; Ruchirawat, Mathuros; Sly, Leith; Sly, Peter D.; Van den Berg, Martin; Suk, William A.

    2015-01-01

    , Van den Berg M, Suk WA. 2016. E-waste and harm to vulnerable populations: a growing global problem. Environ Health Perspect 124:550–555; http://dx.doi.org/10.1289/ehp.1509699 PMID:26418733

  1. Early changes in 25-hydroxyvitamin D levelsand bone markers after monthly risedronatewith cholecalciferol in Korean patients with osteoporosis

    Directory of Open Access Journals (Sweden)

    Chung HY

    2013-05-01

    Full Text Available Ho Yeon Chung,1 Jawon Koo,1 Su Kyoung Kwon,2 Moo-IL Kang,3 Seong-Hwan Moon,4 Jin-Young Park,5 Chan Soo Shin,6 Byung-Koo Yoon,7 Hyun-Koo Yoon,8 Jae-Suk Chang,9 Yoon-Sok Chung,10 Hyoung-Moo Park111Department of Internal Medicine, Kyung Hee University, 2Department of Statistics, 3Department of Internal Medicine, Catholic University of Korea, 4Department of Orthopedics, Yonsei University, 5Department of Orthopedics, Konkuk University, 6Department of Internal Medicine, Seoul National University, 7Department of Obstetrics and Gynecology, Sungkyunkwan University, 8Department of Internal Medicine, Kwandong University, 9Department of Orthopedics, University of Ulsan, Seoul, South Korea; 10Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea; 11Department of Obstetrics and Gynecology, Chung-Ang University, Seoul, South KoreaPurpose: This study investigated the efficacy and safety of monthly risedronate, with and without cholecalciferol, on 25-hydroxyvitamin D (25[OH]D levels and bone markers in Korean patients with osteoporosis.Methods: A randomized, double-blinded, prospective, 16-week clinical trial was conducted in ten hospitals. A total of 150 subjects with osteoporosis were randomized to one of the two treatment groups: RSDM+ (monthly risedronate 150 mg and cholecalciferol 30,000 IU combined in a single pill, n = 74 or RSDM (monthly risedronate 150 mg alone, n = 76. We measured serum levels of 25-hydroxyvitamin D (25[OH]D, parathyroid hormone (PTH, and bone markers, as well as performing muscle-function tests at baseline and after 16 weeks of treatment.Results: After 16 weeks, serum 25(OHD levels significantly increased from 17.8 to 26.8 ng/mL in the RSDM+ group, but did not change in the RSDM group. The RSDM+ group exhibited significantly decreased serum PTH from 46 to 36.7 pg/mL, while the RSDM group showed a tendency for PTH to increase from 38 to 40.6 pg/mL. In both groups, serum bone

  2. Music and the Nature: Input of the Czech Composers

    Science.gov (United States)

    Nemec, Vaclav; Nemcova, Lidmila

    2014-05-01

    Slovak mountains. Josef Suk (1874 - 1935): Pohádka léta (A Summer's Tale) - a work for orchestra remembering a relax and consolation in beauties of the Nature. Bohuslav Martinů (1890 - 1959): Otvírání studánek (The Opening of the Springs) - cantata for soli, female chorus and instrumental accompaniment remembering old local customs of purifying water in the wells when spring comes.

  3. Association of serum ferritin levels with smoking and lung function in the Korean adult population: analysis of the fourth and fifth Korean National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Lee CH

    2016-11-01

    Full Text Available Chan Ho Lee, Eun Kyung Goag, Su Hwan Lee, Kyung Soo Chung, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Joo Han Song Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Institute of Chest Disease, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea Background: Iron-catalyzed oxidative stress contributes to lung injury after exposure to various toxins, including cigarette smoke. An oxidant/antioxidant imbalance is considered to play a critical role in the pathogenesis of COPD. Ferritin is a key protein in iron homeostasis, and its capacity to oxidize and sequester the metal preventing iron prooxidant activity implicates its possible role in the alteration of antioxidant imbalance. We investigated the relationship among cigarette smoking, lung function, and serum ferritin concentration in a large cohort representative of the Korean adult population. Materials and methods: Among 50,405 participants of the Korean National Health and Nutrition Examination Survey from 2010 to 2014, 15,239 adult subjects older than 40 years with serum ferritin levels and spirometric data were selected for this study. Results: The mean age was 56.5 years for men (43% and 56.9 years for women (57%. The prevalence of airway obstruction was 13.4%, which was significantly higher in men than in women, and increased in former or current smokers. The median levels of serum ferritin were highest in the airway obstruction group, followed by the restrictive pattern group, and lowest in the normal lung function group. The median ferritin levels were increased by smoking status and amounts in each spirometric subgroup. In multivariable regression analysis, serum ferritin was positively associated with forced expiratory volume in 1 second and forced expiratory volume in 1 second/forced vital capacity, whereas the smoking amount was negatively associated with the adjustment with age, sex, height

  4. Enzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery

    Directory of Open Access Journals (Sweden)

    Lee SJ

    2015-08-01

    Full Text Available Sang Joon Lee,1,* Young-Il Jeong,2,* Hyung-Kyu Park,3 Dae Hwan Kang,2,4 Jong-Suk Oh,3 Sam-Gyu Lee,5 Hyun Chul Lee31Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju, 2Biomedical Research Institute, Pusan National University Hospital, Busan, 3Department of Microbiology, Chonnam National University Medical School, Gwangju, 4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongnam, 5Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea*These authors contributed equally to this workBackground: Since cancer cells are normally over-expressed cathepsin B, we synthesized dendrimer-methoxy poly(ethylene glycol (MPEG-doxorubicin (DOX conjugates using a cathepsin B-cleavable peptide for anticancer drug targeting.Methods: Gly-Phe-Leu-Gly peptide was conjugated with the carboxylic acid end groups of a dendrimer, which was then conjugated with MPEG amine and doxorubicin by aid of carbodiimide chemistry (abbreviated as DendGDP. Dendrimer-MPEG-DOX conjugates without Gly-Phe-Leu-Gly peptide linkage was also synthesized for comparison (DendDP. Nanoparticles were then prepared using a dialysis procedure.Results: The synthesized DendGDP was confirmed with 1H nuclear magnetic resonance spectroscopy. The DendDP and DendGDP nanoparticles had a small particle size of less than 200 nm and had a spherical morphology. DendGDP had cathepsin B-sensitive drug release properties while DendDP did not show cathepsin B sensitivity. Further, DendGDP had improved anticancer activity when compared with doxorubicin or DendDP in an in vivo CT26 tumor xenograft model, ie, the volume of the CT26 tumor xenograft was significantly inhibited when compared with xenografts treated with doxorubicin or DendDP nanoparticles. The DendGDP nanoparticles were found to be relatively concentrated in the tumor tissue and

  5. Biodegradation and detoxification of textile azo dyes by bacterial consortium under sequential microaerophilic/aerobic processes.

    Science.gov (United States)

    Lade, Harshad; Kadam, Avinash; Paul, Diby; Govindwar, Sanjay

    2015-01-01

    Release of textile azo dyes to the environment is an issue of health concern while the use of microorganisms has proved to be the best option for remediation. Thus, in the present study, a bacterial consortium consisting of Providencia rettgeri strain HSL1 and Pseudomonas sp. SUK1 has been investigated for degradation and detoxification of structurally different azo dyes. The consortium showed 98-99 % decolorization of all the selected azo dyes viz. Reactive Black 5 (RB 5), Reactive Orange 16 (RO 16), Disperse Red 78 (DR 78) and Direct Red 81 (DR 81) within 12 to 30 h at 100 mg L(-1) concentration at 30 ± 0.2 °C under microaerophilic, sequential aerobic/microaerophilic and microaerophilic/aerobic processes. However, decolorization under microaerophilic conditions viz. RB 5 (0.26 mM), RO 16 (0.18 mM), DR 78 (0.20 mM) and DR 81 (0.23 mM) and sequential aerobic/microaerophilic processes viz. RB 5 (0.08 mM), RO 16 (0.06 mM), DR 78 (0.07 mM) and DR 81 (0.09 mM) resulted into the formation of aromatic amines. In distinction, sequential microaerophilic/ aerobic process doesn't show the formation of amines. Additionally, 62-72 % reduction in total organic carbon content was observed in all the dyes decolorized broths under sequential microaerophilic/aerobic processes suggesting the efficacy of method in mineralization of dyes. Notable induction within the levels of azoreductase and NADH-DCIP reductase (97 and 229 % for RB 5, 55 and 160 % for RO 16, 63 and 196 % for DR 78, 108 and 258 % for DR 81) observed under sequential microaerophilic/aerobic processes suggested their critical involvements in the initial breakdown of azo bonds, whereas, a slight increase in the levels of laccase and veratryl alcohol oxidase confirmed subsequent oxidation of formed amines. Also, the acute toxicity assay with Daphnia magna revealed the nontoxic nature of the dye-degraded metabolites under sequential microaerophilic/aerobic processes. As biodegradation under sequential microaerophilic

  6. Dual-function synthetic peptide derived from BMP4 for highly efficient tumor targeting and antiangiogenesis

    Directory of Open Access Journals (Sweden)

    Choi SH

    2016-09-01

    Full Text Available Suk Hyun Choi,1,* Jue Yeon Lee,2,* Jin Sook Suh,1 Yoon Shin Park,3 Chong Pyoung Chung,2 Yoon Jeong Park1 1Department of Dental Regenerative Biotechnology, Dental Research Institute, 2Central Research Institute, Nano Intelligent Biomedical Engineering Corporation (NIBEC, School of Dentistry, Seoul National University, Seoul, 3Department in Microbiology, School of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, South Korea *These authors contributed equally to this work Abstract: Angiogenesis plays a critical role in the growth and metastasis of cancer, and growth factors released from cancer promote blood-vessel formation in the tumor microenvironment. The angiogenesis is accelerated via interactions of growth factors with the high-affinity receptors on cancer cells. In particular, heparan sulfate proteoglycans (HSPGs on the surface of cancer cells have been shown to be important in many aspects of determining a tumor’s phenotype and development. Specifically, the regulation of the interactions between HSPGs and growth factors results in changes in tumor progression. A peptide with heparin-binding (HBP activity has been developed and synthesized to inhibit tumor growth via the prevention of angiogenesis. We hypothesized that HBP could inhibit the interaction of growth factors and HSPGs on the surface of cancer cells, decrease paracrine signaling in endothelial cells (ECs, and finally decrease angiogenesis in the tumor microenvironment. In this study, we found that HBP had antiangiogenic effects in vitro and in vivo. The conditioned media obtained from a breast cancer cell line treated with HBP were used to culture human umbilical vein ECs (HUVECs to evaluate the antiangiogenic effect of HBP on ECs. HBP effectively inhibited the migration, invasion, and tube formation of HUVECs in vitro. In addition, the expressions of angiogenesis-mediating factors, including ERK, FAK, and Akt, were considerably

  7. Comorbidity as a contributor to frequent severe acute exacerbation in COPD patients

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    Jeong SH

    2016-08-01

    Full Text Available Suk Hyeon Jeong,1,* Hyun Lee,1,* KC Carriere,2,3 Sun Hye Shin,1 Seong Mi Moon,1 Byeong-Ho Jeong,1 Won-Jung Koh,1 Hye Yun Park1 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; 2Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, Alberta, Canada; 3Biostatistics and Clinical Epidemiology Center, Samsung Medical Center, Seoul, South Korea *These authors contributed equally to this work Background: Comorbidities have a serious impact on the frequent severe acute exacerbations (AEs in patients with COPD. Previous studies have used the Charlson comorbidity index to represent a conglomerate of comorbidities; however, the respective contribution of each coexisting disease to the frequent severe AEs remains unclear.Methods: A retrospective, observational study was performed in 77 COPD patients who experienced severe AE between January 2012 and December 2014 and had at least 1-year follow-up period from the date of admission for severe AE. We explored the incidence of frequent severe AEs (≥2 severe AEs during 1-year period in these patients and investigated COPD-related factors and comorbidities as potential risk factors of these exacerbations.Results: Out of 77 patients, 61 patients (79.2% had at least one comorbidity. During a 1-year follow-up period, 29 patients (37.7% experienced frequent severe AEs, approximately two-thirds (n=19 of which occurred within the first 90 days after admission. Compared with patients not experiencing frequent severe AEs, these patients were more likely to have poor lung function and receive home oxygen therapy and long-term oral steroids. In multiple logistic regression analysis, coexisting asthma (adjusted odds ratio [OR] =4.02, 95% confidence interval [CI] =1.30–12.46, P=0.016, home oxygen therapy (adjusted OR =9.39, 95% CI =1.60–55.30, P=0.013, and C-reactive protein

  8. Speak up! Speak out! Building HIV and AIDS awareness among Jamaican school children.

    Science.gov (United States)

    Brissett, D; Griffiths-Irving, J

    2008-06-01

    The Government of Jamaica, through the Ministry of Health and other ministries, assisted by international funding agencies and members of non-governmental organizations, has diligently led the charge to reduce the incidence ofHIV and AIDS in Jamaica. Yet, the continued escalation in the infection rate attested to the need for education towards the reduction of stigma and discrimination, factors that fuel the spread of the virus. Significant efforts were made to woo corporations in Jamaica to redouble their efforts and provide resources to address the continued escalation of the AIDS epidemic in Jamaica. Scotiabank Jamaica responded with a unique educational initiative. The Scotiabank National Primary Schools HIV and AIDS Debating Competition in 2006-2007 was conducted over a seven-month period. It was opened to primary-level, government and private institutions islandwide. A total of91 institutions competed with each other debating 16 moots (i.e., topics) in 417 debates from the first preliminary rounds through to the final. Moots reflected curricular and extracurricular concerns, emphasized the values of compassion, healthy lifestyles, critical thinking and child rights; they also sent messages of anti-discrimination, and parental and community responsibilities. Whereas communication between the organizers and the schools was sometimes challenging, schools subscribed to the activity (debates) for the awareness it brought and for the potential for developing students. Attempts were also made to raise awareness among teachers, parents and the general community. Feedback at the end acclaimed the debates as a valuable strategy for building awareness as well as development of student potential and unity around a common cause.

  9. Numerical simulation of steady turbulent flow through trileaflet aortic heart valves--II. Results on five models.

    Science.gov (United States)

    Stevenson, D M; Yoganathan, A P; Williams, F P

    1985-01-01

    Turbulent flow simulations are run for five aortic trileaflet valve geometries, ranging from a valve leaflet orifice area of 1.1 cm2 (Model A1--very stenotic) to 5.0 cm2 (Model A5--natural valve). The simulated data compares well with experimental measurements made downstream of various aortic trileaflet valves by Woo (PhD Thesis, 1984). The location and approximate width and length of recirculation regions are correctly predicted. The less stenotic valve models reattach at the end of the aortic sinus region, 1.1 diameters downstream of the valve. The central jet exiting the less stenotic valve models is not significantly different from fully developed flow, and therefore recovers very quickly downstream of the reattachment point. The more stenotic valves disturb the flow to a greater degree, generating recirculation regions large enough to escape the sinuses and reattach further downstream. Peak turbulent shear stress values downstream of the aortic valve models which approximated prosthetic valves are 125 and 300 Nm-2, very near experimental observations of 150 to 350 Nm-2. The predicted Reynolds stress profiles also present the correct shape, a double peak profile, with the location of the peak occurring at the location of maximum velocity gradient, which occurs near the recirculation region. The pressure drop across model A2 (leaflet orifice area 1.6 cm2) is 20 mmHg at 1.6 diameters downstream. This compares well with values ranging from 19.5 to 26.2 mmHg for valves of similar orifice areas. The pressure drop decreases with decreasing valve stenosis, to a negligible value across the least stenotic valve model. Based on the good agreement between experimental measurements of velocity, shear stress and pressure drop, compared to the simulated data, the model has the potential to be a valuable tool in the analysis of heart valve designs.

  10. Effective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterization

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    Jung IW

    2014-05-01

    Full Text Available Il-Woo Jung, Hyo-Kyung HanCollege of Pharmacy, Dongguk University-Seoul, Ilsan-Donggu, Goyang, Republic of KoreaAbstract: In this work, we aimed to develop chitosan-coated mucoadhesive liposomes ­containing risedronate to improve intestinal drug absorption. Liposomes containing risedronate were prepared with 1,2-distearoryl-sn-glycero-3-phosphocholine and distearoryl-sn-glycero-3-[phospho-rac-(1-glycerol] using the freeze-drying method, with subsequent coating of the anionic surfaces of the liposomes with chitosan. The in vitro characteristics of the chitosan-coated liposomes were investigated, including their stability, mucoadhesiveness, and Caco-2 cell permeability. This formulation was stable in simulated gastric and intestinal fluids, with the percentage of drug remaining in the liposomes being more than 90% after 24 hours of incubation. Chitosan-coated liposomes also showed strong mucoadhesive properties, implying potential electrostatic interaction with the mucous layer in the gastrointestinal tract. Compared with the untreated drug, chitosan-coated liposomes significantly enhanced the cellular uptake of risedronate, resulting in an approximately 2.1–2.6-fold increase in Caco-2 cells. Further, the chitosan-coated liposomes increased the oral exposure of risedronate by three-fold in rats. Taken together, the results of this study suggest that chitosan-coated liposomes containing risedronate should be effective for improving the bioavailability of risedronate.Keywords: cellular uptake, bioavailability, mucoadhesiveness, liposome, chitosan

  11. Some Dust/Ocean Connections - Past, Present, and Future

    Science.gov (United States)

    Duce, R. A.

    2015-12-01

    Atmospheric dust has been the subject of communications for more than 3000 years, since the ancient Chinese book Chronicles Reported on Bamboo Shoots in 1150 BC. Similar reports of hwangsa and woo-tou in ancient Korean and kosa in ancient Japanese literature also indicated major Asian dust events in those areas. Western observers noted dust storms in India and Afghanistan in the early 1800s, while in the 1840s Darwin surmised that Sahara dust could be an important component of marine sedimentation in the North Atlantic. More recent interest has focused on the importance of dust as a source of the nutrients iron and phosphorus in the global ocean and the role of iron as a limiting nutrient in many areas of the surface ocean. While significant progress has been made in the past 25 years in identifying important dust/ocean connections, many issues remain. Included are the relative dearth of long-term measurements of atmospheric dust (and iron and phosphorus) over and deposition to the ocean, especially in the southern hemisphere; comparisons between modeled and measured deposition of dust to the ocean; and the solubility of iron and phosphorus (and thus their availability as nutrients) after the mineral matter enters the ocean. Addressing these problems will certainly help to provide more accurate estimates of the input of dust to the ocean and its impacts. However, future changes in dust emissions in a warmer world as well as changes in the acid/base environment that mineral dust experiences during its transport and deposition as a result of emission controls on atmospheric NOx and SO2 are two facors that may change the input of these nutrients to the ocean and their impacts in the coming years. These and other issues will be reviewed in this paper.

  12. The response and recovery of the Arabidopsis thaliana transcriptome to phosphate starvation

    KAUST Repository

    Woo, Jongchan

    2012-05-03

    Background: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant phosphate metabolism and its underlying genetic pathways is key to discovering methods of efficient fertilizer usage. The work presented here describes a genome-wide resource on the molecular dynamics underpinning the response and recovery in roots and shoots of Arabidopsis thaliana to phosphate-starvation.Results: Genome-wide profiling by micro- and tiling-arrays (accessible from GEO: GSE34004) revealed minimal overlap between root and shoot transcriptomes suggesting two independent phosphate-starvation regulons. Novel gene expression patterns were detected for over 1000 candidates and were classified as either initial, persistent, or latent responders. Comparative analysis to AtGenExpress identified cohorts of genes co-regulated across multiple stimuli. The hormone ABA displayed a dominant role in regulating many phosphate-responsive candidates. Analysis of co-regulation enabled the determination of specific versus generic members of closely related gene families with respect to phosphate-starvation. Thus, among others, we showed that PHR1-regulated members of closely related phosphate-responsive families (PHT1;1, PHT1;7-9, SPX1-3, and PHO1;H1) display greater specificity to phosphate-starvation than their more generic counterparts. Conclusion: Our results uncover much larger, staged responses to phosphate-starvation than previously described. To our knowledge, this work describes the most complete genome-wide data on plant nutrient stress to-date. 2012 Woo et al.; licensee BioMed Central Ltd.

  13. Cationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint

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    Kim SR

    2015-08-01

    Full Text Available Sung Rae Kim,1 Myoung Jin Ho,2 Eugene Lee,3 Joon Woo Lee,3 Young Wook Choi,1 Myung Joo Kang21College of Pharmacy, Chung-Ang University, Dongjak-gu, Seoul, 2College of Pharmacy, Dankook University, Dongnam-gu, Cheonan, Chungnam, 3Department of Radiology, Seoul National University Bundang Hospital, Bundang-gu, Seongnam, Gyeonggi-do, South KoreaAbstract: Positively surface-charged poly(lactide-co-glycolide (PLGA/Eudragit RL nanoparticles (NPs were designed to increase retention time and sustain release profile in joints after intra-articular injection, by forming micrometer-sized electrostatic aggregates with hyaluronic acid, an endogenous anionic polysaccharide found in high amounts in synovial fluid. The cationic NPs consisting of PLGA, Eudragit RL, and polyvinyl alcohol were fabricated by solvent evaporation technique. The NPs were 170.1 nm in size, with a zeta potential of 21.3 mV in phosphate-buffered saline. Hyperspectral imaging (CytoViva® revealed the formation of the micrometer-sized filamentous aggregates upon admixing, due to electrostatic interaction between NPs and the polysaccharides. NPs loaded with a fluorescent probe (1,1'-dioctadecyl-3,3,3',3' tetramethylindotricarbocyanine iodide, DiR displayed a significantly improved retention time in the knee joint, with over 50% preservation of the fluorescent signal 28 days after injection. When DiR solution was injected intra-articularly, the fluorescence levels rapidly decreased to 30% of the initial concentration within 3 days in mice. From these findings, we suggest that PLGA-based cationic NPs could be a promising tool for prolonged delivery of therapeutic agents in joints selectively.Keywords: PLGA, Eudragit RL, hyaluronic acid, cationic nanoparticles, intra-articular injection, electrostatic interaction

  14. Estimation of health state utilities in breast cancer

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    Kim SH

    2017-03-01

    Full Text Available Seon-Ha Kim,1 Min-Woo Jo,2 Minsu Ock,2 Hyeon-Jeong Lee,2 Jong-Won Lee3,4 1Department of Nursing, College of Nursing, Dankook University, Cheonan, 2Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, 3Department of Breast and Endocrine Surgery, Asan Medical Center, Seoul, 4Department of Surgery, University of Ulsan College of Medicine, Seoul, South Korea Purpose: The aim of this study is to determine the utility of breast cancer health states using the standard gamble (SG and visual analog scale (VAS methods in the Korean general population.Materials and methods: Eight hypothetical breast cancer health states were developed based on patient education material and previous publications. Data from 509 individuals from the Korean general population were used to evaluate breast cancer health states using the VAS and the SG methods, which were obtained via computer-assisted personal interviews. Mean utility values were calculated for each human papillomavirus (HPV-related health state.Results: The rank of health states was identical between two valuation methods. SG values were higher than VAS values in all health states. The utility values derived from SG were 0.801 (noninvasive breast cancer with mastectomy and followed by reconstruction, 0.790 (noninvasive breast cancer with mastectomy only, 0.779 (noninvasive breast cancer with breast-conserving surgery and radiation therapy, 0.731 (invasive breast cancer with surgery, radiation therapy, and/or chemotherapy, 0.610 (locally advanced breast cancer with radical mastectomy with radiation therapy, 0.587 (inoperable locally advanced breast cancer, 0.496 (loco-regional recurrent breast cancer, and 0.352 (metastatic breast cancer.Conclusion: Our findings might be useful for economic evaluation of breast cancer screening and interventions in general populations. Keywords: breast neoplasm, Korea, quality-adjusted life years, quality of life

  15. Variable Mixed Orbital Character in the Photoelectron Angular Distribution of NO_{2}

    Science.gov (United States)

    Laws, Benjamin A.; Cavanagh, Steven J.; Lewis, Brenton R.; Gibson, Stephen T.

    2017-06-01

    NO_{2} a key component of photochemical smog and an important species in the Earth's atmosphere, is an example of a molecule which exhibits significant mixed orbital character in the HOMO. In photoelectron experiments the geometric properties of the parent anion orbital are reflected in the photoelectron angular distribution (PAD), an area of research that has benefited largely from the ability of velocity-map imaging (VMI) to simultaneously record both the energetic and angular information, with 100% collection efficiency. Photoelectron spectra of NO_{2}^{-}, taken over a range of wavelengths (355nm-520nm) with the ANU's VMI spectrometer, reveal an anomalous jump in the anisotropy parameter near threshold. Consequently, the orbital behavior of NO_{2}^{-} appears to be quite different near threshold compared to detachment at higher photon energies. This surprising effect is due to the Wigner Threshold law, which causes p orbital character to dominate the photodetachment cross-section near threshold, before the mixed s/d orbital character becomes significant at higher electron kinetic energies. By extending recent work on binary character models to form a more general expression, the variable mixed orbital character of NO_{2}^{-} is able to be described. This study provides the first multi-wavelength NO_{2} anisotropy data, which is shown to be in decent agreement with much earlier zero-core model predictions of the anisotropy parameter. K. J. Reed, A. H. Zimmerman, H. C. Andersen, and J. I. Brauman, J. Chem. Phys. 64, 1368, (1976). doi:10.1063/1.432404 D. Khuseynov, C. C. Blackstone, L. M. Culberson, and A. Sanov, J. Chem. Phys. 141, 124312, (2014). doi:10.1063/1.4896241 W. B. Clodius, R. M. Stehman, and S. B. Woo, Phys. Rev. A. 28, 760, (1983). doi:10.1103/PhysRevA.28.760 Research supported by the Australian Research Council Discovery Project Grant DP160102585

  16. Prevalence of colorectal adenomatous polyps in patients with chronic obstructive pulmonary disease

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    Chun EM

    2015-05-01

    Full Text Available Eun Mi Chun, Seo Woo Kim, So Yeon Lim Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Republic of Korea Background: Colorectal adenomatous polyps are precancerous lesions of colorectal cancer. The aim of this study was to assess the prevalence of colorectal adenomatous polyps in chronic obstructive pulmonary disease (COPD patients and determine whether COPD is associated with colorectal malignant potential.Methods: Subjects who had undergone post-bronchodilator spirometry and colonoscopy and were 40 years or older were selected from the hospital database. COPD was defined as a spirometry in which the ratio of forced expiratory volume in 1 second (FEV1 and forced vital capacity (FVC is <0.7 in post-bronchodilator spirometry. The non-COPD group was matched for both age and sex, and were defined as having an FEV1, FVC, and FEV1/FVC ≥0.7 in spirometry. Finally, 333 patients were retrospectively reviewed; of this group, 82 patients had COPD.Results: Among the subjects, 201 patients (60% were nonsmokers, while 78 (23% were current smokers. The prevalence of colorectal adenomatous polyps was 39% (98/251 in the non-COPD group and 66% (54/82 in the COPD group. Among 54 patients with adenomatous polyps in the COPD group, 47 had tubular adenoma and seven had villous adenoma. Multiple logistic regression analyses revealed that only COPD patients whom matched to the criteria of COPD by pulmonary function test (odds ratio 2.1, 95% confidence interval: 1.1–3.8; P=0.019 were independently associated with colorectal malignant potential.Conclusion: The risk of colorectal malignant potential in the COPD group was higher than in the non-COPD group. We may suggest that COPD patients should consider regular colonoscopic evaluation to screen for premalignant colon polyps regardless of smoking. Keywords: COPD, colorectal adenomatous polyp, smoking, chronic obstructive pulmonary

  17. Validation of a quantitative 12-multigene expression assay (Oncotype DX® Colon Cancer Assay in Korean patients with stage II colon cancer: implication of ethnic differences contributing to differences in gene expression

    Directory of Open Access Journals (Sweden)

    Jeong DH

    2015-12-01

    Full Text Available Duck Hyoun Jeong,1 Woo Ram Kim,1 Byung Soh Min,1 Young Wan Kim,2 Mi Kyung Song,3 Nam Kyu Kim1 1Department of Surgery, Yonsei University College of Medicine, Seoul, 2Department of Surgery, Wonju College of Medicine, Wonju, 3Department of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea Purpose: To evaluate the Recurrence Score® of the quantitative 12-multigene expression assay and to determine risk groups based on the continuous Recurrence Score® in Korean patients.Method: A total of 95 patients with pathological T3N0 tumors and mismatch repair-proficient tumors were enrolled. The Recurrence Score® was used to classify risk groups (low risk, <30; intermediate risk, 30–40; high risk, ≥41.Results: Fifty-four patients (56.8% were aged over 70 years. There were 49 men (51.6% and 56 cases of right-sided colon cancer (58.9%. Eight cases (8.4% had well-differentiated tumors, and 86 cases (90.5% showed moderate differentiation. Only one case (1.1% had a poorly differentiated tumor. Three patients (3.2% had lymphovascular invasion. Sixty-one patients were identified as low risk (64.2% and 34 patients as intermediate risk (35.8%. There were no high-risk patients. Although not significant, the 3-year recurrence risk increased with the Recurrence Score®.Conclusion: Distribution patterns of risk groups based on the Recurrence Score®, particularly the absence of a high-risk group, were different from the prior validation studies. These findings suggest that ethnic differences between Koreans and Western patients are potential contributing factors for different gene expressions in the quantitative 12-multigene expression assay. Keywords: colonic neoplasms, gene expression, adjuvant chemotherapy, ethnic groups

  18. Validation of sensor for postoperative positioning with intraocular gas

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    Brodie FL

    2016-05-01

    Full Text Available Frank L Brodie,1 Kelly Y Woo,2 Ashwin Balakrishna,2 Hyuck Choo,2 Robert H Grubbs2 1Department of Ophthalmology, University of California San Francisco, San Francisco, 2Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA Purpose: Surgical repair of retinal attachment or macular hole frequently requires intraocular gas. This necessitates specific postoperative positioning to improve outcomes and avoid complications. However, patients struggle with correct positioning. We have developed a novel sensor to detect the position of the gas bubble in the eye and provide feedback to patients in real time. In this paper, we determine the specificity and sensitivity of our sensor in vitro using a model eye. Methods: We assessed the reliability of our sensor to detect when a gas bubble has deviated off a model retinal break in a model eye. Various bubble sizes representing the intraocular kinetics of sulfur hexafluoride gas and varying degrees of deviation from the correct position were tested using the sensor attached to a mannequin head with a model eye. Results: We recorded 36 data points. The sensor acted appropriately in 33 (91.7% of them. The sensor triggered the alarm every time the bubble deviated off the break (n=15, sensitivity =100%. However, it triggered the alarm (falsely 3/21 times when the bubble was correctly positioned over the retinal break (specificity =86%. Conclusion: Our device shows excellent sensitivity (100% and specificity (86% in detecting whether intraocular gas is tamponading a retinal break in a model eye. Keywords: postoperative positioning, intraocular gas, vitrectomy, retinal detachment, macular hole, pneumatic retinopexy

  19. Lurasidone as a potential therapy for bipolar disorder

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    Woo YS

    2013-10-01

    Full Text Available Young Sup Woo, Hee Ryung Wang, Won-Myong Bahk Department of Psychiatry, Yeouido St Mary's Hospital, The Catholic University of Korea, Seoul, Korea Abstract: Lurasidone is a benzisothiazol derivative and an atypical antipsychotic approved by the US Food and Drug Administration for the acute treatment of adults with schizophrenia (October 2010 and bipolar 1 depression (June 2013. Lurasidone has a strong antagonistic property at the D2, serotonin (5-HT2A, and 5-HT7 receptors, and partial agonistic property at the 5-HT1A receptor. Lurasidone also has lower binding affinity for the α2C and 5-HT2C receptor. Lurasidone is rapidly absorbed (time to maximum plasma concentration: 1–3 hours, metabolized mainly by CYP3A4 and eliminated by hepatic metabolism. In two large, well-designed, 6-week trials in adult patients with bipolar 1 depression, lurasidone monotherapy and adjunctive therapy with mood stabilizers were significantly more effective than placebo at improving depressive symptoms assessed using the Montgomery–Åsberg Depression Rating Scale total score. In both trials, lurasidone also reduced the Clinical Global Impression–Bipolar Severity depression score to a greater extent than placebo. In these two trials, discontinuation rates due to adverse events in the lurasidone group were small (<7% and were not different from those of the placebo group. The most common adverse events in the lurasidone group were headache, nausea, somnolence, and akathisia. The changes in lipid profiles, weight, and parameters of glycemic control were minimal, and these findings were in line with those observed in schizophrenia trials. Further active comparator trials and long-term tolerability and safety data in bipolar patients are required. Lurasidone may be an option for the management of depressive symptoms in patients with bipolar 1 disorder, and it may be considered as a treatment alternative for patients who are at high risk for metabolic abnormalities

  20. Quantum magnetic excitations from stripes in copper-oxide superconductors

    Science.gov (United States)

    Tranquada, John

    2005-03-01

    Recent inelastic neutron scattering studies show that the magnetic excitation spectra of two well-studied families of cuprate superconductors are much more similar than previously believed. In particular, I will present results we have obtained on La2-xBaxCuO4 (LBCO) with x = 0.125 [1,2]. Using very large single crystals grown at Brookhaven, we were able to measure the magnetic excitations up to 200 meV using the MAPS time-of-flight spectrometer at the ISIS spallation source. While the lowest energy excitations are split incommensurately, these disperse inwards towards the antiferromagnetic wave vector with increasing energy, merging at ˜50 meV. At higher energies the excitations disperse outwards again. There is a significant enhancement of the Q-integrated magnetic scattering near ˜50 meV compared to lower energies, suggestive of quantum correlations and distinct from spin-wave predictions. Many features of the spectrum are quite similar to those found in YBa2Cu3O6.6 [3]. One can qualitatively characterize the results with a universal excitation spectrum, together with a material-dependent spin gap in the superconducting state. It is important to note that the LBCO sample exhibits static stripe order [2], as this has significant implications for the origin of the magnetic excitations in superconducting cuprates. *J. M. Tranquada, H. Woo, T. G. Perring, H. Goka, G. D. Gu, G. Xu, M. Fujita, and K. Yamada, Nature 429, 534 (2004). *M. Fujita, H. Goka, K. Yamada, J. M. Tranquada, and L.-P. Regnault, Phys. Rev. B 70, 104517 (2004). *S. M. Hayden, H. A. Mook, P. C. Dai, T. G. Perring, and F. Dogan, Nature 429, 531 (2004).

  1. Alpha-synuclein in cutaneous small nerve fibers

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    Siepmann T

    2016-10-01

    Full Text Available Timo Siepmann,1 Ben Min-Woo Illigens,2 Kristian Barlinn1 1Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; 2Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA Abstract: Despite progression in the development of pharmacological therapy, treatment of alpha synucleinopathies, such as Parkinson’s disease (PD and some atypical parkinsonism syndromes, is still challenging. To date, our knowledge of the mechanisms whereby the pathological form of alpha-synuclein causes structural and functional damage to the nervous system is limited and, consequently, there is a lack of specific diagnostic tools to evaluate pathology in these patients and differentiate PD from other neurodegenerative proteinopathies. Recent studies indicated that alpha-synuclein deposition in cutaneous small nerve fibers assessed by skin biopsies might be a valid disease marker of PD and facilitate early differentiation of PD from atypical parkinsonism syndromes. This observation is relevant since early diagnosis may enable timely treatment and improve quality of life. However, challenges include the necessity of standardizing immunohistochemical analysis techniques and the identification of potential distinct patterns of intraneural alpha-synuclein deposition among synucleinopathies. In this perspective, we explore the scientific and clinical opportunities arising from alpha-synuclein assessment using skin biopsies. These include elucidation of the peripheral nervous system pathology of PD and other synucleinopathies, identification of novel targets to study response to neuroprotective treatment, and improvement of clinical management. Furthermore, we discuss future challenges in exploring the diagnostic value of skin biopsy assessment for alpha-synuclein deposition and implementing the technique in clinical practice. Keywords: Parkinson’s disease, diagnosis, skin

  2. Stealth nanotubes: strategies of shielding carbon nanotubes to evade opsonization and improve biodistribution

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    Kotagiri N

    2014-05-01

    Full Text Available Nalinikanth Kotagiri,1–4 Jin-Woo Kim1–31Bio/Nano Technology Laboratory, Institute for Nanoscience and Engineering, 2Department of Biological and Agricultural Engineering, 3Cell and Molecular Biology Graduate Program, University of Arkansas, Fayetteville, AR, USA; 4Optical Radiology Laboratory, Department of Radiology, Washington University School of Medicine, St Louis, MO, USAAbstract: Carbon nanotubes (CNTs have recently been in the limelight for their potential role in disease diagnostics and therapeutics, as well as in tissue engineering. Before these medical applications can be realized, there is a need to address issues like opsonization, phagocytosis by macrophages, and sequestration to the liver and spleen for eventual elimination from the body; along with equally important issues such as aqueous solubility, dispersion, biocompatibility, and biofunctionalization. CNTs have not been shown to be able to evade such biological obstacles, which include their nonspecific attachments to cells and other biological components in the bloodstream, before reaching target tissues and cells in vivo. This will eventually determine their longevity in circulation and clearance rate from the body. This review article discusses the current status, challenges, practical strategies, and implementations of coating CNTs with biocompatible and opsonin-resistant moieties, rendering CNTs transparent to opsonins and deceiving the innate immune response to make believe that the CNTs are not foreign. A holistic approach to the development of such "stealth" CNTs is presented, which encompasses not only several biophysicochemical factors that are not limited to surface treatment of CNTs, but also extraneous biological factors such as the protein corona formation that inevitably controls the in vivo fate of the particles. This review also discusses the present and potential applications, along with the future directions, of CNTs and their hybrid

  3. KEMATIAN ANAK DAN UMUR HARAPAN HIDUP DI NAGGROE ACEH DARUSSALAM

    Directory of Open Access Journals (Sweden)

    S. Soemantri

    2012-07-01

    Full Text Available Surkesda NAD 2006 collected birth history data reported by ever married women of the householdsamples. Birth history data were used to estimate childhood mortality for Nanggroe Aceh Darussalam(NAD. Both direct and indirect estimation of childhood mortality were applied. Indirect estimationused Coale Demeny West model (Trussel equations and UN general model (Palloni-Heligmanequations. Both direct and indirect estimation of childhood mortality surprisingly gave similarestimates of Infant Mortality Rate (IMR. Child Mortality Rate (CMR or Under-five Mortality Rate(U5MR for the period about five years before survey. Estimates of IMR. CMR and U5MR wererespectively 48 per 1000, 15 per WOO and 62 per 1000. The estimate of IMR of 48 per 1000 is muchhigher than estimate for NAD based on BPS Population Projection, i.e. 39-40 per 1000 for 2000-2005. Life expectancy at birth for NAD derived from Coale Demeny West model for IMR 48 per 1000 ormortality level of about 20. was 65.5 years. This figure is lower than BPS projection of life expectancyat birth for NAD which was 67.2 years. Direct estimation approach indicated the rise of childhoodmortality recently, which may be due to the impact of earth quake/tsunami that hit NAD in 2004. Therise of childhood mortality could not be recognized by indirect estimation approach. The rise ofmortality recently may be true since disaster of earth quake/tsunami had hampered the availability ofhealth personnel (doctors and midwives and household environment (accessibility to safe water or safetoilet. There is an indication of the negative relationship between availability of doctors and midwives,or accessibility of safe water and safe toilet with childhood survivorship in NAD. Keyword: IMR, CMR, U5MR, life expectency

  4. Translation from research to applications.

    Science.gov (United States)

    Hunziker, Ernst; Spector, Myron; Libera, Jeanette; Gertzman, Arthur; Woo, Savio L-Y; Ratcliffe, Anthony; Lysaght, Michael; Coury, Arthur; Kaplan, David; Vunjak-Novakovic, Gordana

    2006-12-01

    The article summarizes the collective views expressed at the fourth session of the workshop Tissue Engineering--the Next Generation, which was devoted to the translation of results of tissue engineering research into applications. Ernst Hunziker described the paradigm of a dual translational approach, and argued that tissue engineering should be guided by the dimensions and physiological setting of the bodily compartment to be repaired. Myron Spector discussed collagen-glycosaminoglycan (GAG) scaffolds for musculoskeletal tissue engineering. Jeanette Libera focused on the biological and clinical aspects of cartilage tissue engineering, and described a completely autologous procedure for engineering cartilage using the patient's own chondrocytes and blood serum. Arthur Gertzman reviewed the applications of allograft tissues in orthopedic surgery, and outlined the potential of allograft tissues as models for biological and medical studies. Savio Woo discussed a list of functional tissue engineering approaches designed to restore the biochemical and biomechanical properties of injured ligaments and tendons to be closer to that of the normal tissues. Specific examples of using biological scaffolds that have chemoattractants as well as growth factors with unique contact guidance properties to improve their healing process were shown. Anthony Ratcliffe discussed the translation of the results of research into products that are profitable and meet regulatory requirements. Michael Lysaght challenged the proposition that commercial and clinical failures of early tissue engineering products demonstrate a need for more focus on basic research. Arthur Coury described the evolution of tissue engineering products based on the example of Genzyme, and how various definitions of success and failure can affect perceptions and policies relative to the status and advancement of the field of tissue engineering.

  5. Aberrant brain-stem morphometry associated with sleep disturbance in drug-naïve subjects with Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Lee JH

    2016-08-01

    Full Text Available Ji Han Lee,1 Won Sang Jung,2 Woo Hee Choi,3 Hyun Kook Lim4 1Washington University in St Louis, St Louis, MO, USA; 2Department of Radiology, 3Department of Nuclear Medicine, 4Department of Psychiatry, Saint Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, South Korea Objective: Among patients with Alzheimer’s disease (AD, sleep disturbances are common and serious noncognitive symptoms. Previous studies of AD patients have identified deformations in the brain stem, which may play an important role in the regulation of sleep. The aim of this study was to further investigate the relationship between sleep disturbances and alterations in brain stem morphology in AD.Materials and methods: In 44 patients with AD and 40 healthy elderly controls, sleep disturbances were measured using the Neuropsychiatry Inventory sleep subscale. We employed magnetic resonance imaging-based automated segmentation tools to examine the relationship between sleep disturbances and changes in brain stem morphology.Results: Analyses of the data from AD subjects revealed significant correlations between the Neuropsychiatry Inventory sleep-subscale scores and structural alterations in the left posterior lateral region of the brain stem, as well as normalized brain stem volumes. In addition, significant group differences in posterior brain stem morphology were observed between the AD group and the control group.Conclusion: This study is the first to analyze an association between sleep disturbances and brain stem morphology in AD. In line with previous findings, this study lends support to the possibility that brain stem structural abnormalities might be important neurobiological mechanisms underlying sleep disturbances associated with AD. Further longitudinal research is needed to confirm these findings. Keywords: Alzheimer’s disease, sleep, brain stem, MRI, shape analysis

  6. Medications and therapeutic apheresis procedures: are we doing our best?

    Science.gov (United States)

    Ibrahim, Rami B; Balogun, Rasheed Abiodun

    2013-02-01

    Therapeutic apheresis refers to a group of extracorporeal therapies commonly used in the treatment of a variety of neurological, renal, hematological, and other systemic diseases caused by circulating "toxic agents" that cannot be cleared by other means. This article presents an overview of the concepts underlying the effect of therapeutic apheresis procedures on prescription drugs taken by patients and describes key drug-related and procedure-related factors that may impact drug disposition during therapeutic apheresis. Therapeutic apheresis, and specifically therapeutic plasma exchange (TPE), is the process involving the extracorporeal separation of plasma from the cellular components of blood, discarding the plasma and exchanging it with replacement physiologic fluids such as albumin or fresh frozen plasma to maintain oncotic pressure and blood volume, and then returning this and the original cellular components of blood back to the patient's circulatory system (Ibrahim and Balogun, Semin Dial 2012;25:176-189). Over the last 4 decades, modern therapeutic apheresis has been used clinically for the treatment of a host of renal, hematological, and neurological diseases such as Goodpasture's syndrome, thrombotic thrombocytopenic purpura, and myasthenia gravis to name a few (Ibrahim et al., Pharmacotherapy 2007;27:1529-1549). Because of its ability to remove plasma, TPE can extract circulating drugs residing in this compartment, thereby affecting their disposition and potentially their therapeutic action (Ibrahim and Balogun, Semin Dial 2012;25:176-189; Ibrahim et al., Pharmacotherapy 2007;27:1529-1549; Kale-Pradhan and Woo, Pharmacotherapy 1997;17:684-695; Kintzel et al., J Clin Apher 2003;18:194-205). The aim of this article is to shed light on drug-related and TPE-related factors that may influence drug removal by TPE. Emphasis is put on areas needing improvement in the way of assessing drug removal by TPE. In addition, a call for an expanded investigation of TPEs

  7. The 2002 HBR list. Breakthrough ideas for today's business agenda.

    Science.gov (United States)

    2002-03-01

    In the last year, war broke out, the economy took a nosedive, and an alarming number of businesses went belly up. Thus it is with some urgency that we bring you this year's list of the seven best new business ideas to help you find your way through these complex times. History Returns. Many thought that the fall of the Berlin Wall marked the beginning of a new world order, one in which history didn't matter. But September 11, 2001, put an end to that theory. And it raised serious questions about globalization, security, and strategy. Enter the Everyday Leader--at Last. CEOs are used to getting all the glory, but leaders outside the limelight--middle managers and tempered radicals--are beginning to receive the attention they deserve. The Internet Is Not About You. The real value of the Internet may lie less in connecting individuals than in connecting databases, servers, and devices--a web not of people but of machines. Mind Your Behavior. Behavioral scientists are beginning to be able to accurately predict the ways individuals and crowds will respond to stimuli, and the implications for business are profound. Don't Delight Your Customers Away. Companies have wooed and coddled customers for too long. The truth is, people delight in being teased and are repelled by those who try too hard to befriend them. Games Are for Losers. Financial game playing and verbal politicking are seriously damaging businesses. Honesty is more than an admirable virtue; it's the foundation of every lasting enterprise. Three Cheers for Creativity (Sometimes). Creativity and best-practice replication are fundamentally different undertakings. Managers who mix the two achieve creativity that is merely incremental and replication that is sadly inept.

  8. Novel antibacterial nanofibrous PLLA scaffolds.

    Science.gov (United States)

    Feng, Kai; Sun, Hongli; Bradley, Mark A; Dupler, Ellen J; Giannobile, William V; Ma, Peter X

    2010-09-15

    In order to achieve high local bioactivity and low systemic side effects of antibiotics in the treatment of dental, periodontal and bone infections, a localized and temporally controlled delivery system is crucial. In this study, a three-dimensional (3-D) porous tissue engineering scaffold was developed with the ability to release antibiotics in a controlled fashion for long-term inhibition of bacterial growth. The highly soluble antibiotic drug, doxycycline (DOXY), was successfully incorporated into PLGA nanospheres using a modified water-in-oil-in-oil (w/o/o) emulsion method. The PLGA nanospheres (NS) were then incorporated into prefabricated nanofibrous PLLA scaffolds with a well interconnected macro-porous structure. The release kinetics of DOXY from four different PLGA NS formulations on a PLLA scaffold was investigated. DOXY could be released from the NS-scaffolds in a locally and temporally controlled manner. The DOXY release is controlled by DOXY diffusion out of the NS and is strongly dependent upon the physical and chemical properties of the PLGA. While PLGA50-6.5K, PLGA50-64K, and PLGA75-113K NS-scaffolds discharge DOXY rapidly with a high initial burst release, PLGA85-142K NS-scaffold can extend the release of DOXY to longer than 6weeks with a low initial burst release. Compared to NS alone, the NS incorporated on a 3-D scaffold had significantly reduced the initial burst release. In vitro antibacterial tests of PLGA85 NS-scaffold demonstrated its ability to inhibit common bacterial growth (S. aureus and E. coli) for a prolonged duration. The successful incorporation of DOXY onto 3-D scaffolds and its controlled release from scaffolds extends the usage of nano-fibrous scaffolds from the delivery of large molecules such as growth factors to the delivery of small hydrophilic drugs, allowing for a broader application and a more complex tissue engineering strategy. 2010 Elsevier B.V. All rights reserved.

  9. What is a free customer worth? Armchair calculations of nonpaying customers' value can lead to flawed strategies.

    Science.gov (United States)

    Gupta, Sunil; Mela, Carl F

    2008-11-01

    Free customers who are subsidized by paying customers are essential to a vast array of businesses, such as media companies, employment services, and even IT providers. But because they generate revenue only indirectly, figuring out the true value of those customers--and how much attention to devote them--has always been a challenge. Traditional customer-valuation models don't help; they focus exclusively on paying customers and largely ignore network effects, or how customers help draw other customers to a business. Now a new model, devised by professors Gupta, of Harvard Business School, and Mela, of Fuqua School of Business, takes into account not only direct network effects (where buyers attract more buyers or sellers more sellers) but also indirect network effects (where buyers attract more sellers or vice versa) . The model calculates the precise long-term impact of each additional free customer on a company's profits, factoring in the degree to which he or she brings in other customers--whether free or paying--and the ripple effect of those customers. The model helped an online auction house make several critical decisions. The business made its money on fees charged to sellers but recognized that its free customers--its buyers--were valuable, too. As competition heated up, the company worried that it wasn't wooing enough buyers. Using the model, the business discovered that the network effects of buyers were indeed large and that those customers were worth over $1,000 each--much more than had been assumed. Armed with that information, the firm increased its research on buyers, invested more in targeting them with ads, and improved their experience. The model also helped the company identify the effects of various pricing strategies on sellers, showing that they became less price-sensitive over time. As a result, the company raised the fees it charged them as well.

  10. CELL RESEARCH

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    REVIEWSInducible resistance to Fas-mediated apoptosis in B cells…………………………………ROTHSTEIN Thomas L (245)Executionary pathway for apoptosis: lessons from mutant mice………………………………………WOO Minna, Razqallah Hakem, Tak W Mak (267)The SHP-2 tyrosine phosphatase: Signaling mechanisms and biological functions…………………………………QU Cheng Kui (279)REGULAR ARTICLESTemperature dependent expression of cdc2 and cyclin B1 in spermatogenic cells during spermatogenesis…………………………KONG Wei Hua, Zheng GU, Jining LU, Jiake TSO (289)Transgenic mice overexpressing γ-aminobutyric acid transporter subtype I develop obesity…………………………………MA Ying Hua, Jia Hua HU, Xiao Gang ZHOU, Ruo Wang ZENG, Zhen Tong MEI, Jian FEI, Li He GUO (303)Genetic aberration in primary hepatocellular carcinoma: correlation between p53 gene mutation and loss-of-heterozygosity on chromosome 16q21-q23 and 9p21-p23………………………………………WANG Gang, Chang Hui HUANG, Yan ZHAO, Ling CAI, Ying WANG, Shi Jin XIU, Zheng Wen JIANG, Shuang YANG, Xin Tai ZHAO, Wei HUANG, Jian Ren GU (311)Identification and genetic mapping of four novel genes that regulate leaf deve- lopment in Arabidopsis………………………………………………SUN Yue, Wei ZHANG, Feng Ling LI, Ying Li GUO, Tian Lei LIU, Hai HUANG (325)NOTICE FOR CONTRIBUTORS…………………………………(337)CONTENTS of Vol. 10, 2000…………………………………………………(338)

  11. Quasi-linear viscoelastic properties of the human medial patello-femoral ligament.

    Science.gov (United States)

    Criscenti, G; De Maria, C; Sebastiani, E; Tei, M; Placella, G; Speziali, A; Vozzi, G; Cerulli, G

    2015-12-16

    The evaluation of viscoelastic properties of human medial patello-femoral ligament is fundamental to understand its physiological function and contribution as stabilizer for the selection of the methods of repair and reconstruction and for the development of scaffolds with adequate mechanical properties. In this work, 12 human specimens were tested to evaluate the time- and history-dependent non linear viscoelastic properties of human medial patello-femoral ligament using the quasi-linear viscoelastic (QLV) theory formulated by Fung et al. (1972) and modified by Abramowitch and Woo (2004). The five constant of the QLV theory, used to describe the instantaneous elastic response and the reduced relaxation function on stress relaxation experiments, were successfully evaluated. It was found that the constant A was 1.21±0.96MPa and the dimensionless constant B was 26.03±4.16. The magnitude of viscous response, the constant C, was 0.11±0.02 and the initial and late relaxation time constants τ1 and τ2 were 6.32±1.76s and 903.47±504.73s respectively. The total stress relaxation was 32.7±4.7%. To validate our results, the obtained constants were used to evaluate peak stresses from a cyclic stress relaxation test on three different specimens. The theoretically predicted values fit the experimental ones demonstrating that the QLV theory could be used to evaluate the viscoelastic properties of the human medial patello-femoral ligament.

  12. The Influence of Nietzsche’s Anthropology on the Works of George Bernard Shaw

    Directory of Open Access Journals (Sweden)

    Biljana Vlašković

    2016-03-01

    Full Text Available This paper identifies the traces of Friedrich Nietzsche’s anthropological philosophy in the dramatic, sociological, anthropological, and philosophical writings of George Bernard Shaw. Apart from the obvious use of Nietzsche’s term “the Superman” (Übermensch to serve the purposes of his own philosophy, the analysis shows further similarities between the two writers, namely that Shaw modified Nietzsche’s expression “the will to power”, as well as Schopenhauer’s concept of will as the world’s essence, and termed it the “Life Force”, which will enable a “creative evolution” of humans into a higher being, an Overman, or a Superman. Also concerning this is the role that Shaw gives to women in this process of creative evolution, by making the female the dominant gender, and in so doing radically deconstructing the deeply rooted 19th century view of woman as a being whose natural habitat is the family home, and whose role in wooing is exclusively passive. Such an attitude led many critics to believe that Shaw was a misogynist of the same kind as Schopenhauer and Nietzsche. However, Shawian discourse as a whole exhibits а vehement support of the feminist struggles for the gender equality, which made the author a favorite in feminist circles. Different perspectives in Shaw’s anthropology mirror Nietzsche’s demand for the “transvaluation of all values”, and this alone is necessary to provide a constant change, which, according to both authors, is the only thing that is certain and constant in this world.

  13. Soil texture reclassification by an ensemble model

    Science.gov (United States)

    Cisty, Milan; Hlavcova, Kamila

    2015-04-01

    Many environmental problems in which soil data serves as an inputs to simulation models are not restricted to national boundaries and therefore require international cooperation if solutions are to be found. The classification of soils according to their texture is one of the basic methods used for soil description. The term "soil texture" indicates the distribution of soil particles in the soil according to their size (diameter). The most preferred representation of texture classification is a grading curve. Because not all countries use the same classification system, databases from these countries cannot provide us with uniform data, which can serve as the inputs for various computations or models. This study deals with a description of a texture system reclassification to USDA classification system by the proposed model on a data set from Slovakia originally labeled by Slovakian national classification system. However, the authors of the paper suppose that the methodology proposed could be used more generally and that the information provided is also applicable when dealing with other existing soil texture classification systems. Some researchers have already proposed to fit the measured PSDs by various continuous parametric grading curves. When gaining such a relationship, it is possible to obtain a granular fraction's percentage ratio in the sample under consideration for any size of the particle diameter, which means that it is possible to get the values necessary for accomplishing a translation from one texture classification system to another. Several authors have conducted comparative studies on various PSD models in order to determine the best model for the soil groups selected for their studies (Nemes et al., 1999; Hwang, 2004; Botula et al., 2013). The reported findings of the abovementioned works somewhat differ from each other, and there is no generally suitable PSD model available. Because the transformation of a soil texture system is usually only

  14. AHR-dependent changes in the mitochondrial proteome in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

    Directory of Open Access Journals (Sweden)

    Hye Jin Hwang

    2016-09-01

    Full Text Available The aryl hydrocarbon receptor (AHR is a ligand-activated transcription factor that is the principal regulator of a cell׳s response to many polyaromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD. To gain a better understanding of the impact of TCDD on the mitochondrial proteome, a stable isotope labeling by amino acids in cell culture (SILAC-based proteomic analysis was performed. We used two mouse hepatoma cell lines that differ in AHR expression levels, hepa1c1c7 (AHR-expressing and hepac12 (AHR-deficient. The cell lines were exposed to TCDD (10 nM for 72 h; each treatment was assayed in triplicate and were analyzed as separate runs on the mass-spectrometer. Mitochondria were then isolated and mitochondrial proteins were separated by SDS-PAGE and subject to mass spectrometry. The data presented were collected from four independent SILAC experiments. Within each experiment, three isotopes were employed to compare protein ratios via mass-spectrometry: (1 light l-arginine/l-lysine HCl (Arg0, Lys0, (2 medium 15N4-l-arginin/13C6l-lysine HCl (Arg4, Lys6, and (3 heavy 13C615N4l-arginine/13C615N2l-lysine HCl (Arg10, Lys8. The raw data includes approximately 2500 annotated proteins. The datasets provided by this study can be a reference to other toxicologists investigating TCDD-induced mitochondrial dysfunction. The data presented here are associated with the research article, “Mitochondrial-targeted Aryl Hydrocarbon Receptor and the Impact of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Cellular Respiration and the Mitochondrial Proteome” (Hwang et al. (2016 [1].

  15. Biosynthesis, characterization, and antimicrobial applications of silver nanoparticles

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    Singh P

    2015-03-01

    Full Text Available Priyanka Singh,1 Yeon Ju Kim,2 Hina Singh,1 Chao Wang,2 Kyu Hyon Hwang,3 Mohamed El-Agamy Farh,1 Deok Chun Yang1,2 1Department of Oriental Medicinal Material and Processing, 2Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, Yongin, 3Gyeonggi-Do Agricultural Research & Extension Services, Gyeonggi, Republic of Korea Abstract: In the present study, the strain Brevibacterium frigoritolerans DC2 was explored for the efficient and extracellular synthesis of silver nanoparticles. These biosynthesized silver nanoparticles were characterized by ultraviolet-visible spectrophotometry, which detected the formation of silver nanoparticles in the reaction mixture and showed a maximum absorbance at 420 nm. In addition, field emission transmission electron microscopy revealed the spherical shape of the nanoparticles. The dynamic light scattering results indicated the average particle size of the product was 97 nm with a 0.191 polydispersity index. Furthermore, the product was analyzed by energy dispersive X-ray spectroscopy, X-ray diffraction, and elemental mapping, which displayed the presence of elemental silver in the product. Moreover, on a medical platform, the product was checked against pathogenic microorganisms including Vibrio parahaemolyticus, Salmonella enterica, Bacillus anthracis, Bacillus cereus, Escherichia coli, and Candida albicans. The nanoparticles demonstrated antimicrobial activity against all of these pathogenic microorganisms. Additionally, the silver nanoparticles were evaluated for their combined effects with the commercial antibiotics lincomycin, oleandomycin, vancomycin, novobiocin, penicillin G, and rifampicin against these pathogenic microorganisms. These results indicated that the combination of antibiotics with biosynthesized silver nanoparticles enhanced the antimicrobial effects of antibiotics. Therefore, the current study is a demonstration of an efficient biological synthesis

  16. Technical and Physical Activities of Small-Sided Games in Young Korean Soccer Players.

    Science.gov (United States)

    Joo, Chang H; Hwang-Bo, Kwan; Jee, Haemi

    2016-08-01

    Joo, CH, Hwang-Bo, K, and Jee, H. Technical and physical activities of small-sided games in young Korean soccer players. J Strength Cond Res 30(8): 2164-2173, 2016-The aim of this study was to examine the technical aspects and physical demands during small-sided games (SSGs) with different sized pitches in young Korean soccer players. Participants were randomly selected during a nationally held youth competition. Three different game formats were used: SSG8 (8 vs. 8 played on a small-sized field [68 × 47 m]), RSG8 (8 vs. 8 played on a regular-sized field [75 × 47 m]), and RSG11 (11 vs. 11 played on a regular-sized field). Eleven technical (ball touches, passes, and shots) and 6 physical demand variables (exercise frequency by intensity) were observed and analyzed. Same variables were also analyzed for the goalkeepers. As a result, SSG8 and RSG8 showed significantly greater numbers of technical plays in 5 and 4 variables in comparison to RSG11, respectively. In addition, although the exercise intensities increased slightly in both SSG formats, the amount was within the similar range as previous reports. In conclusion, the SSGs with reduced number of players may be referred in young players to effectively train them in technical aspects of the game by allowing greater ball exposure time without excessive physical demands. Various confounding factors such as pitch dimension should be carefully considered for training specific technical and physical variables in young Korean players.

  17. Characterization of standard embeddings between complex Grassmannians by means of varieties of minimal rational tangents

    Institute of Scientific and Technical Information of China (English)

    MOK Ngaiming

    2008-01-01

    In 1993,Tsai proved that a proper holomorphic mapping f : Ω→Ω' from an irreducible bounded symmetric domain Ω of rank ≥ 2 into a bounded symmetric domain Ω' is necessarily totally geodesic provided that r' : = rank(Ω') ≤ rank(Ω) := r,proving a conjecture of the author's motivated by Hermitian metric rigidity.As a first step in the proof,Tsai showed that df preserves almost everywhere the set of tangent vectors of rank 1.Identifying bounded symmetric domains as open subsets of their compact duals by means of the Borel embedding,this means that the germ of f at a general point preserves the varieties of minimal rational tangents (VMRTs).In another completely different direction Hwang-Mok established with very few exceptions the Cartan-Fubini extension priniciple for germs of local biholomorphisms between Fano manifolds of Picard num-ber 1,showing that the germ of map extends to a global biholomorphism provided that it preserves VMRTs.We propose to isolate the problem of characterization of special holomorphic embeddings between Fano manifolds of Picard number 1,especially in the case of classical manifolds such as ratio-nal homogeneous spaces of Picard number 1,by a non-equidimensional analogue of the Cartan-Fubini extension principle.As an illustration we show along this line that standard embeddings between com-plex Grassmahn manifolds of rank ≤ 2 can be characterized by the VMRT-preserving property and a non-degeneracy condition,giving a new proof of a result of Neretin's which on the one hand paves the way for far-reaching generalizations to the context of rational homogeneous spaces and more generally Fano manifolds of Picard number 1,on the other hand should be applicable to the study of proper holomorphic mappings between bounded domains carrying some form of geometric structures.

  18. Conflicts of Discourse Power Displayed in M. Butterfly%《蝴蝶君》的话语权之争

    Institute of Scientific and Technical Information of China (English)

    陈尚坤

    2011-01-01

    黄哲伦的《蝴蝶君》以人物聚散的离奇情节与细腻的心理刻画有力地颠覆了东方对西方依存关系的虚假命题。作者在其作品中试图解构东方主义、反击文化殖民并颠覆西方殖民话语权。由于作者的文化身份、成长经历以及他身处的社会历史环境的局限性,作品对东方主义的解构是有限的,特别是剧中人宋利伶的角色本身就是一个矛盾体:一方面他被看作是颠覆殖民话语的一次努力尝试,另一方面角色本身却强化了西方对东方的固有成见。%David Hwang's M. Butterfly subverts the pseudo-hypothesis of the Oriental reliance on the Occident with its exceptional arrangement of plots and delicate depiction of dramatis personae. Hwang tries to deconstruct Orientalism, retort culture colonialism and topple down the discourse power of western colonialism. Due to Hwang's cultural identity, personal life as well as the social settings he experienced every day, M. Butterfly only partly subverts Orientalism. Particularly, the dra matis persona, Song, is a paradoxical creation: While he is often considered to be the author's effort to subvert the colonial discourse power, he has actually strengthened the West's stereotyped bias against the East.

  19. Improving the Accuracy of a Heliocentric Potential (HCP) Prediction Model for the Aviation Radiation Dose

    Science.gov (United States)

    Hwang, Junga; Yoon, Kyoung-Won; Jo, Gyeongbok; Noh, Sung-Jun

    2016-12-01

    The space radiation dose over air routes including polar routes should be carefully considered, especially when space weather shows sudden disturbances such as coronal mass ejections (CMEs), flares, and accompanying solar energetic particle events. We recently established a heliocentric potential (HCP) prediction model for real-time operation of the CARI-6 and CARI-6M programs. Specifically, the HCP value is used as a critical input value in the CARI-6/6M programs, which estimate the aviation route dose based on the effective dose rate. The CARI-6/6M approach is the most widely used technique, and the programs can be obtained from the U.S. Federal Aviation Administration (FAA). However, HCP values are given at a one month delay on the FAA official webpage, which makes it difficult to obtain real-time information on the aviation route dose. In order to overcome this critical limitation regarding the time delay for space weather customers, we developed a HCP prediction model based on sunspot number variations (Hwang et al. 2015). In this paper, we focus on improvements to our HCP prediction model and update it with neutron monitoring data. We found that the most accurate method to derive the HCP value involves (1) real-time daily sunspot assessments, (2) predictions of the daily HCP by our prediction algorithm, and (3) calculations of the resultant daily effective dose rate. Additionally, we also derived the HCP prediction algorithm in this paper by using ground neutron counts. With the compensation stemming from the use of ground neutron count data, the newly developed HCP prediction model was improved.

  20. Primary percutaneous coronary intervention ameliorates complete atrioventricular block complicating acute inferior myocardial infarction

    Directory of Open Access Journals (Sweden)

    Lee SN

    2014-11-01

    Full Text Available Su Nam Lee, You-Mi Hwang, Gee-Hee Kim, Ji-Hoon Kim, Ki-Dong Yoo, Chul-Min Kim, Keon-Woong MoonDepartment of Internal Medicine, St Vincent’s Hospital, The Catholic University of Korea, Suwon, South KoreaObjective: Complete atrioventricular block (CAVB in acute inferior ST-segment elevation myocardial infarction (STEMI is associated with poor clinical outcomes after noninvasive treatment. This study was designed to determine the effect of primary percutaneous coronary intervention (PCI in patients with CAVB complicating acute inferior STEMI, at a single center.Methods: We enrolled 138 consecutive patients diagnosed with STEMI involving the inferior wall; of these, 27 patients had CAVB. All patients received primary PCI. The clinical characteristics, procedural data, and clinical outcomes were compared in patients with versus without CAVB. Results: Baseline clinical characteristics were similar between patients with and without CAVB. Patients with CAVB were more likely to present with cardiogenic shock, and CAVB was caused primarily by right coronary artery occlusion. Door-to-balloon time was similar between those two groups. After primary PCI, CAVB was reversed in all patients. The peak creatinine phosphokinase level, left ventricular ejection fraction and in-hospital mortality rate were similar between the two groups. After a median follow up of 318 days, major adverse cardiac events did not differ between the groups (8.1% in patients without CAVB; 11.1% in patients with CAVB (P=0.702.Conclusion: We conclude that primary PCI can ameliorate CAVB-complicated acute inferior STEMI, with an acceptable rate of major adverse cardiac events, and suggest that primary PCI should be the preferred reperfusion therapy in patients with CAVB complicating acute inferior myocardial infarction. Keywords: major adverse cardiac events, PCI-capable hospital