WorldWideScience

Sample records for hwan kim jong

  1. The New North Korean Problem: History and Responsibilities in the Age of Kim Jong Un

    Science.gov (United States)

    2012-03-29

    Kim Jong Un is the youngest of Kim Jong Il’s three male children. The oldest, Kim Jong Nam was once favored to...passport.49 In a series of interviews with Japanese reporter Yogi Gomi, Kim Jong Nam related his concerns about the future of North Korea and the...4. TITLE AND SUBTITLE THE NEW NORTH KOREAN PROBLEM: HISTORY AND RESPONSIBILITIES IN THE AGE OF KIM JONG UN 5. FUNDING NUMBERS

  2. Projecting Pyongyang: The Future of North Korea's Kim Jong IL Regime

    National Research Council Canada - National Science Library

    Scobell, Andrew

    2008-01-01

    .... In this monograph, the focus is on the fate of the regime dominated by the Kim Dynasty, initially ruled by Kim Il Sung and then led by his son, Kim Jong Il, following the former's death in 1994...

  3. REPRESENTATION OF KIM JONG-UN’S SUCCESSION IN BBC NEWS: A CRITICAL DISCOURSE ANALYSIS

    Directory of Open Access Journals (Sweden)

    Hendra Nugraha

    2016-04-01

    Full Text Available This research attempts to reveal representation of Kim Jong-Un’s succession in BBC News through textual and discursive practice analysis. The data of this thesis are taken from BBC News website on 29 and 31 December 2011. The theory applied to seek the objective of the research is Critical Discourse Analysis developed by Fairclough. Through textual and discursive practice analysis, the writer finds pthat BBC employs more passive material clauses than active material clauses in depicting Kim Jong-Un’s succession. BBC also represents Kim Jong-Un’s succession as premature process where Kim Jong-Un is portrayed as a young and inexperienced leader. Besides the prematurity of the succession, the present writer finds that BBC represents Kim Jong-Un’s succession as continuity of Kim’s family dynasty. Thus, the succession is based on his resemblance to Kim Il-Sung, the founder of Democratic People’s Republic of Korea, rather than Kim Jong-Un ability and competency.

  4. Prospects for 6-party talks: Nuclear weapons are a means of survival for Kim Jong Un

    International Nuclear Information System (INIS)

    Miyake, Kunihiko

    2012-04-01

    The author considers the impact of leader Kim Jong Il's death on 6-party talks surrounding the nuclear issue. Firstly, the history of these 6-party talks has to be reexamined to ensure an accurate understanding of their 'objectives and limitations' because the author believes that there are 3 'unpleasant truths' behind these talks, held 6 times since the summer of 2003, that no one wants to talk about. 1. North Korea has no interest in abandoning nuclear weapons; 2. Japan, the U.S., China, and South Korea do not want war; 3. The nuclear issue will not be resolved by 6-party talks. In fact, there is little potential that 6-party talks which aim to resolve the North Korean nuclear issue will move towards a new substantive agreement

  5. North Korean Leadership Dynamics and Decision-making under Kim Jong-un: A First Year Assessment

    Science.gov (United States)

    2013-09-01

    Kim Jong-un’s ’Sick’ Aunt Resurfaces,” Chosun Ilbo Online, 27 July 2013. Kim has a reported history of alcoholism and depression , which was...exacer- bated in the mid-2000s with her marital problems and the death of her daughter, Jang Kum-song, who committed suicide in 2006. Some reports claim...the Party and state apparatus. She was born in 1974, and, when in her teens , began work in Kim Il-sung’s Presidential Office. She moved over to the

  6. Social influence of a religious hero: the late Cardinal Stephen Kim Sou-hwan's effect on cornea donation and volunteerism.

    Science.gov (United States)

    Bae, Hyuhn-Suhck; Brown, William J; Kang, Seok

    2011-01-01

    This study examined the mediated influence of a celebrated religious hero in South Korea, Cardinal Stephen Kim, through two forms of involvement--parasocial interaction and identification--on intention toward cornea donation and volunteerism, and it investigated how the news media diffused of his death. A structural equation modeling analysis with a Web-based voluntary survey of more than 1,200 people in South Korea revealed a multistep social influence process, beginning with parasocial interaction with Cardinal Kim, leading to identification with him, which predicted intention toward cornea donation and volunteerism. Additional investigations found that news of Cardinal Kim's death diffused rapidly through media and interpersonal communication. Results of this study demonstrate that religious leaders who achieve a celebrity hero status can prompt public discussion of important issues rather quickly through extensive media coverage, enabling them to promote prosocial behavior and positively affect public health.

  7. North Korean Leadership Dynamics and Decision-making under Kim Jong-un: A Second Year Assessment

    Science.gov (United States)

    2014-03-01

    Kim Kyong-hui was critically ill. Kim has a reported history of alcoholism and depression , which was exacerbated in the mid-2000s with her mari- tal...problems and the death of her daughter, Jang Kum-song, who com- mitted suicide in 2006. Some reports claim that she is also suffering from... teens , were

  8. Lõuna-Korea teatel võib Kim peagi surra / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    Viidates Lõuna-Korea ja Hiina luureandmetele, väidab Lõuna-Korea meedia, et Põhja-Korea liidril Kim Jong-ilil on kõhunäärmevähk ja talle pole antud elada rohkem kui 5 aastat. Põhja-Korea valitsejadünastia

  9. North Korea’s Provocation and Escalation Calculus: Dealing with the Kim Jong-un Regime

    Science.gov (United States)

    2015-08-01

    regime. “The Interview” In the early 2000s, Seth Rogan and Evan Goldberg conceived of a plot for a comic take on the assassination of a world...responsible for the education and training of the regime’s cyber warriors.55  The State Security Department’s (secret police) communications monitoring and...is young and lacks the expansive and deep education his father had before taking the reins of power. This has created a certain narrative in the

  10. Results from KIMS

    International Nuclear Information System (INIS)

    Myung, S. S.; Bhang, H. C.; Choi, J. H.; Kim, D. W.; Kim, S. C.; Kim, S. K.; Kwak, J. W.; Lee, J.; Lee, J. H.; Lee, M. J.; Lee, S. J.; Ryu, S.; Kang, W. G.; Kim, Y. D.; Lee, J. I.; Jung, S. W.; Kim, H. J.; So, J. H.; Hahn, I. S.; Hwang, M. J.

    2008-01-01

    KIMS is a dark matter search experiment using low background CsI(TB) crystals at Yangyang Underground Laboratory in Korea. With a total exposure of 3409 kg·d data, we set a new limit on WIMP-nucleon cross section. We achieved the most stringent limit on the spin-dependent interaction for a pure proton case. We were able to exclude the DAMA signal region for both spin-dependent and spin-independent interaction for the WIMP mass greater than 20 GeV/c 2 . KIMS experiment is upgraded with 12 CsI(TB) crystals corresponding to a total mass of 104 kg and accumulating data since Jan. 2008.

  11. The ten thousand Kims

    Science.gov (United States)

    Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

    2011-07-01

    In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

  12. The ten thousand Kims

    International Nuclear Information System (INIS)

    Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

    2011-01-01

    In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

  13. Geloof en geluk: traditie en vernieuwing bij jonge moslims

    NARCIS (Netherlands)

    Korf, D.J.; Wouters, M.; Place, S.; Koet, S.

    2008-01-01

    FORUM doet in een jaarlijkse monitor verslag van de ontwikkelingen en trends onder jonge moslims. Het doel daarvan is vroegtijdig signaleren, volgen en duiden van trends in opvattingen, belevingen en gedragingen van jonge moslims in Nederland. Het onderzoek Geloof en geluk is het resultaat van de

  14. Een theoretische exercitie over de zorgverantwoordelijkheid van jonge mantelzorgers

    NARCIS (Netherlands)

    Deirdre Beneken genaamd Kolmer; Gert Evers

    2014-01-01

    In het recent gepubliceerde boek “Jonge mantelzorgers en hun zorgverantwoordelijkheid voor naaste familieleden” wordt antwoord gegeven op de vraag “In hoeverre is het wenselijk dat jonge mantelzorgers zorgen voor naaste familieleden?” Om deze vraag te beantwoorden is allereerst een literatuurstudie

  15. Monte Carlo lattice program KIM

    International Nuclear Information System (INIS)

    Cupini, E.; De Matteis, A.; Simonini, R.

    1980-01-01

    The Monte Carlo program KIM solves the steady-state linear neutron transport equation for a fixed-source problem or, by successive fixed-source runs, for the eigenvalue problem, in a two-dimensional thermal reactor lattice. Fluxes and reaction rates are the main quantities computed by the program, from which power distribution and few-group averaged cross sections are derived. The simulation ranges from 10 MeV to zero and includes anisotropic and inelastic scattering in the fast energy region, the epithermal Doppler broadening of the resonances of some nuclides, and the thermalization phenomenon by taking into account the thermal velocity distribution of some molecules. Besides the well known combinatorial geometry, the program allows complex configurations to be represented by a discrete set of points, an approach greatly improving calculation speed

  16. Electric Power Research in 1991

    International Nuclear Information System (INIS)

    1991-05-01

    This book of contents are a study of desalination by Kim, Young Bu, a study on efficiency test for nuclear power security by Jo, Sung Je; Ann, Nam Sung; Kim, Ho Gi, augmentation of EMS and RYU by Jung, Tae Hoe; Shin, Young Chuel, research on application for electric cars by Yu, Ann Gue, practical use oft robot for nuclear industry by Woo, He Gone; Shin, Hen Beom, a study on the characteristics of coolant structure in generator by Choi, Beng Hwan; Song, Young Chel; Kim, Jong Hark, and research of penetration rate of appliances by Park, Hong Ho; Kim, Beng Cheal; Kim, Dong Hwen.

  17. Goede vangsten jonge haring en wijting: weinig kabeljauw: International Bottom Trawl Survey 2001

    NARCIS (Netherlands)

    Heessen, H.J.L.

    2001-01-01

    Onderzoeksvaartuigen hebben de bestandsopname van jonge haring en rondvis uitgevoerd in de Noordzee, het Skagerrak en het Kattegat. Overzicht van de bestanden van kabeljauw, schelvis, wijting, haring, sprot en makreel 1977-2001

  18. Piezoelectric Nanogenerators for Self-Powered Nanosystems and Nanosensors

    Science.gov (United States)

    2013-05-15

    researchers 1. Sangmin Lee, Sung-Hwan Bae, Long Lin, Seunghyun Ahn, Chan Park, Seung Nam Cha, Young Jun Park, Hyuk Chang, Sang-Woo Kim and...Sohn, Seung Nam Cha, Dukhyun Choi * Zhong Lin Wang * Sang-Woo Kim * “ P-Type Polymer–Hybridized High-Performance Piezoelectric Nanogenerators”, Nano...Yoon Lee, † Sang-Woo Kim , *,$ Jae-Young Choi, *,† Jong Min Kim , † and Zhong Lin Wang *, “Flexible Hybrid Multi-Type Energy Scavenger”, Energy

  19. Effects of Gyejibongnyeong-hwan on dysmenorrhea caused by blood stagnation: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Park Jeong-Su

    2012-01-01

    Full Text Available Abstract Background Gyejibongnyeong-hwan (GJBNH is one of the most popular Korean medicine formulas for menstrual pain of dysmenorrhea. The concept of blood stagnation in Korean medicine is considered the main factor of causing abdominal pain, or cramps, during menstrual periods. To treat the symptoms, GJBNH is used to fluidify the stagnated blood and induce the blood flow to be smooth, reducing pain as the result. The purpose of this trial is to identify the efficacy of GJBNH in dysmenorrhea caused by blood stagnation. Methods This study is a multi-centre, randomised, double-blind, controlled trial with two parallel arms: the group taking GJBNH and the group taking placebo. 100 patients (women from age 18 to 35 will be enrolled to the trial. Through randomization 50 patients will be in experiment arm, and the other 50 patients will be in control arm. At the second visit (baseline, all participants who were already screened that they fulfil both the inclusion and the exclusion criteria will be randomised into two groups. Each group will take the intervention three times per day during two menstrual cycles. After the treatment for two cycles, each patient will be followed up during their 3rd, 4th and 5th menstrual cycles. From the screening (Visit 1 through the second follow-up (Visit 6 the entire process will take 25 weeks. Discussion This trial will provide evidence for the effectiveness of GJBNH in treating periodical pain due to dysmenorrhea that is caused by blood stagnation. The primary outcome between the two groups will be measured by changes in the Visual Analogue Score (VAS of pain. The secondary outcome will be measured by the Blood Stagnation Scale, the Short-form McGill questionnaire and the COX menstrual symptom scale. Analysis of covariance (ANCOVA and repeated measured ANOVA will be used to analyze the data analysis. Trial registration Current Controlled Trials: ISRCTN30426947

  20. El energúmeno misógino: la réplica feminista de Erica Jong a Nicanor Parra

    Directory of Open Access Journals (Sweden)

    Oscar Sarmiento

    2016-07-01

    Full Text Available This article explores the poetic reply by Erica Jong to a poem written by Nicanor Parra. The poetic self of Jong’s poem - “Men” - adopts the satirical stance of the self in Parra’s poem - “Mujeres” - to introduce a radical alteration of perspectives. While the feminist objective of Jong is to debunk the vitriolic anti-women discourse of Parra’s neurotic character, her reply also reveals the asymmetrical gender context of cultural production and reader reception of Parra’s antipoem. Though she contests his sexism, Jong also shows a nuanced appreciation of the male writer’s nonconformist work.

  1. Practice makes perfect: the neural substrates of tactile discrimination by Mah-Jong experts include the primary visual cortex

    Directory of Open Access Journals (Sweden)

    Honda Manabu

    2006-12-01

    Full Text Available Abstract Background It has yet to be determined whether visual-tactile cross-modal plasticity due to visual deprivation, particularly in the primary visual cortex (V1, is solely due to visual deprivation or if it is a result of long-term tactile training. Here we conducted an fMRI study with normally-sighted participants who had undergone long-term training on the tactile shape discrimination of the two dimensional (2D shapes on Mah-Jong tiles (Mah-Jong experts. Eight Mah-Jong experts and twelve healthy volunteers who were naïve to Mah-Jong performed a tactile shape matching task using Mah-Jong tiles with no visual input. Furthermore, seven out of eight experts performed a tactile shape matching task with unfamiliar 2D Braille characters. Results When participants performed tactile discrimination of Mah-Jong tiles, the left lateral occipital cortex (LO and V1 were activated in the well-trained subjects. In the naïve subjects, the LO was activated but V1 was not activated. Both the LO and V1 of the well-trained subjects were activated during Braille tactile discrimination tasks. Conclusion The activation of V1 in subjects trained in tactile discrimination may represent altered cross-modal responses as a result of long-term training.

  2. Kim Dotcomi kättemaks / Andy Greenberg

    Index Scriptorium Estoniae

    Greenberg, Andy

    2013-01-01

    Skandaalne Internetimagnaat Kim Schmitz, rohkem tuntud kui Kim Dotcom, on veendunud, et tema loodud failivahetusprogrammi Megauploadi mahavõtmisega ja autoriõiguste rikkumise süüdistusega tehti talle liiga ning ta on asunud raevukalt vastulöögile USA valitsuse vastu

  3. A Study of China’s Possible Military Intervention in the Event of a Sudden Change in North Korea

    Science.gov (United States)

    2011-06-10

    Kim Jong - nam , Kim Jong -chul or Kim Jong -un as Kim‘s successor. Some have asserted that there might not be a third generation of Kim ...The power struggle between Kim Jong - nam (eldest son) who is residing in China and Kim Jong -un has been observed in many places over time. Kim 29... Jong - nam , who is known to be receiving Chinese support, revealed his opposition to a third generation of dynastic succession in

  4. Coenite seiklused ja Kim Ki-duki huumor / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  5. Prikljutshenija Koenov i jumor Kim Ki-duka / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  6. Global Policing and the Case of Kim Dotcom

    OpenAIRE

    Darren Palmer; Ian J Warren

    2013-01-01

    In early 2012, 76 heavily armed police conducted a raid on a house in Auckland, New Zealand. The targets were Kim Dotcom, a German national with a NZ residency visa, and several colleagues affiliated with Megaupload, an online subscription-based peer-to-peer (P2P) file sharing facility. The alleged offences involved facilitating unlawful file sharing and United States federal criminal copyright violations. Following the raid, several court cases provide valuable insights into emerging ‘global...

  7. Chang Sei Kim's Activities on Public Health in Colonial Korea

    Directory of Open Access Journals (Sweden)

    Park Yunjae

    2006-12-01

    Full Text Available After graduating from Severance Medical College in 1916, Chang Sei Kim went to Shanghai to work as a missionary in a adventist hospital. The establishment of the Korean Provisional Government led him to participate in the independence movement. Educating nurses to assist the forthcoming war for independence, he seemed to realize the fact that the health of Koreans would be a key factor for achieving independence. He left for the U.S. to conduct comprehensive research on medicine. Chang Sei Kim was the first Korean to receive a Ph. D. degree of Public Health, graduating from the Johns Hopkins School of Hygiene and Public Health in 1925. He then gained an opportunity to work for Korea as a professor at Severance Medical College. His objective was the 'Reconstruction of the Korean People In Terms of Physical Constitution.' He pointed out that Koreans' weak state of health was a major reason for Korea's colonization. To gain independence, he emphasized that the Korean people should receive education on public health in order to improve the primitive conditions of sanitation. There is little doubt that Chang Sei Kim's ideas developed Heungsadan's views on medicine in terms of its stress on cultivation of ability, especially considering the fact that he was a member of the organization. As a member of the colonized who could not participate in the developing official policy, Chang Sei Kim was not able to implement his ideas fully, because an individual or a private organization could not carry out policy on public health as large a scale as the government did. Never giving up his hopes for Korean independence, he rejected requests to assume official posts in the Government-General. That was why he was particularly interested in the Self-Governing Movement in 1920s Korea. If the movement had attained its goal, he might have worked for the enhancement of sanitary environment as a director of Sanitary Department. His application for funding to establish

  8. Anmeldelse af Kim Wind Andersen: Overblik over selskabers underskudsfremførsel

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2011-01-01

    Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)......Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)...

  9. Kim C. Sturgess. Shakespeare and the American Nation.

    Directory of Open Access Journals (Sweden)

    Jean‑Louis Claret

    2006-04-01

    Full Text Available The front page of Kim C Sturgess’s recent book entitled Shakespeare and the American Nation is particularly mind‑teasing insofar as it represents the famous Droeshout engraving of the bard (it illustrated the front‑page of the 1623 edition of Shakespeare’s works standing out against a background that superimposes the head of the Statue of Liberty on the spangled banner. The starting point of Sturgess’s 234‑page demonstration endorsed by Cambridge University Press is a paradox that the Britis...

  10. Kim C. Sturgess. Shakespeare and the American Nation.

    OpenAIRE

    Claret, Jean‑Louis

    2006-01-01

    The front page of Kim C Sturgess’s recent book entitled Shakespeare and the American Nation is particularly mind‑teasing insofar as it represents the famous Droeshout engraving of the bard (it illustrated the front‑page of the 1623 edition of Shakespeare’s works) standing out against a background that superimposes the head of the Statue of Liberty on the spangled banner. The starting point of Sturgess’s 234‑page demonstration endorsed by Cambridge University Press is a paradox that the Britis...

  11. Sexualidad violenta en el cine de Kim Ki-duk

    Directory of Open Access Journals (Sweden)

    Daniel Muñoz Ruiz

    2011-07-01

    Full Text Available En sus más de 110 años de vida el cine ha representado la sexualidad humana en todas sus modalidades y desde los más variados puntos de vista. El cine de Kim Ki-duk ha sorprendido y escandalizado al público por su crudeza y, a veces, excesiva violencia. El director surcoreano ha explorado a lo largo de su filmografía el tema del sexo siempre desde puntos de vista dramáticos y hasta truculentos. En sus películas la mayoría de las relaciones sexuales carecen de amor y afecto. Nunca son placenteras. La violación, la prostitución, la violencia de género y las frustraciones sexuales son temas recurrentes en su cine.

  12. Materialismo percettivo. Da Democrito a Lenin, da Hobbes a Kim

    Directory of Open Access Journals (Sweden)

    Michele Gardini

    2012-05-01

    Full Text Available The paper tries to outline something like a short “critique of pure materialism” in the domain of perception, a sketch showing – through a series of examples, picked out in an apparently heterogeneous fashion from the Western philosophical tradition – how this epistemological model each time, and in everyone of its forms, fails in giving account of the basic features of perceiving.  After giving a survey of authors like Democritus, Hobbes, De Sade, Lenin, the final appendix, devoted to the concept of “supervenience” and its treatment in Davidson and Kim, aims at summarizing the whole problem through the categories of the contemporary philosophy of mind. The conclusion is that a pure materialistic approach is incapable to give reason to some of the fundamental characteristics of perception, that make it one of the basic moods of “being-in-the-world”.

  13. Global Policing and the Case of Kim Dotcom

    Directory of Open Access Journals (Sweden)

    Darren Palmer

    2013-11-01

    Full Text Available In early 2012, 76 heavily armed police conducted a raid on a house in Auckland, New Zealand. The targets were Kim Dotcom, a German national with a NZ residency visa, and several colleagues affiliated with Megaupload, an online subscription-based peer-to-peer (P2P file sharing facility. The alleged offences involved facilitating unlawful file sharing and United States federal criminal copyright violations. Following the raid, several court cases provide valuable insights into emerging ‘global policing’ practices (Bowling and Sheptycki 2012 based on communications between sovereign enforcement agencies.  This article uses these cases to explore the growth of ‘extraterritorial’ police powers that operate ‘across borders’ (Nadelmann 1993 as part of several broader transformations of global policing in the digital age.

  14. Magnetic flux creep in HTSC and Anderson-Kim theory

    International Nuclear Information System (INIS)

    Lykov, A.N.

    2014-01-01

    The theoretical and experimental data on flux creep in high-temperature superconductors (HTSC) were analyzed in the review paper. On the one hand, the main attention is paid to the most striking experimental results which have had a significant influence on the investigations of flux creep in HTSC. On the other hand, the analysis of theoretical studies is concentrated on the works, which explain the features of flux creep on the basis of the Anderson-Kim (AK) theory modifications, and received previously unsufficient attention. However, it turned out that the modified AK theory could explain a lot of features of flux creep in HTSC: the scaling behaviour of current-voltage curves of HTSC, the finite rate of flux creep at ultra low temperatures, the logarithmic dependence of effective pinning potential as a function of transport current and its decrease with temperature. The harmonic potential field which is used in this approach makes it possible to solve accurately the both problems: viscous vortex motion and flux creep in this field. Moreover the distribution of pinning potential and the interaction of vortices with each other are taken into account in the approach. Thus, the modification of the AK theory consists, essentially, in its detailed elaboration and approaching to real situations in superconductors

  15. Konrad Ottenheym and Krista De Jonge (eds., The Low Countries at the Crossroads. Netherlandish Architecture as an Export Product in Early Modern Europe (1480-1680

    Directory of Open Access Journals (Sweden)

    Oliver Kik

    2015-12-01

    Full Text Available Book review of: Konrad Ottenheym & Krista De Jonge (eds., The Low Countries at the Crossroads. Netherlandish Architecture as an Export Product in Early Modern Europe (1480-1680, (Architectura Moderna, vol. VIII. Turnhout, Brepols, 2013. 514 pp. ISBN 978-2-503-54333-8. € 130,00.

  16. A STUDY OF MICROBES IN FRUIT JUICES, KIMS-AMALAPURAM

    Directory of Open Access Journals (Sweden)

    Nagaraja

    2015-12-01

    Full Text Available INTRODUCTION Fruit and sugarcane juices are nutritious drinks with great taste and health benefits. Food borne illnesses associated with consumption of Fruit and sugarcane juices at several places in India and elsewhere. Fruit juices were served with added ice pieces. Hygienic standards are not maintained while transporting from the field to the place of extraction and preparation. Hence a rapid review of the fruit juices from street vendors has been undertaken along with sugarcane juice. Raw sugarcane juice is a refreshing juice in many parts of Andhra Pradesh. The present study is to assess the prevalence of different organisms from different fruit juices collected from street vendors. METHODS Fruit juices are collected namely sugarcane, sweet lemon, orange, grape apple, pineapple pomegranate. A total 100 samples of fruit juices were collected from road side from different vendors. 150 ml of each variety of fruit juices were collected from different vendors in screw capped bottles and subjected to microbial analysis, processed with in 30mts in the department of microbiology at KIMS by standard methods. RESULTS The analysed samples of fruit juices are found to be contaminated with different bacteria, Escherichia coli 30% Klebsiella pneumoniae 10% Staphylococcus aureus 20% Enterococcus faecalis 04% Pseudomonas aeruginosa 10% ASB 04% (aerobic spore bearers Micrococci 02% Proteus 20% Salmonella. Shigella and Vibrios were not isolated. CONCLUSION It is high time that street vendors should have health education by volunteers, health workers from PHC (primary health centers and people well versed with community medicine practice for implementation of standard hygienic protocols may reduce contamination of fruit and sugarcane juices The concerned health authorities need to ensure and insist to follow the protocols by the vendors and license holders to the vendors.

  17. Kritiese geletterdheid: Die ontmoeting tussen die Westerse sekularisme en Islamitiese spiritualiteit in geselekteerde romans vir jong volwasseness – 'n benadering

    Directory of Open Access Journals (Sweden)

    Salome Romylos

    2016-11-01

    Full Text Available Hierdie artikel het ten doel om aan te toon dat die geselekteerde romans vir jong volwassenes potensieel kragtige ruimtes kan wees vir die skep van ’n bewustheid en beter begrip van Moslems, Islam, en veral van die dra van sluiers en kopdoeke. Kritiese geletterdheid as ’n metodologie word gebruik om te demonstreer hoe leerders gelei kan word om krities betrokke te raak by tekste. Dit is noodsaaklik, omdat blote oppervlakkennis nie genoeg is wanneer leerders gekonfronteer word met ingewikkelde kwessies soos ras, spiritualiteit en kultuur nie. Westerse televisie, koerante en tydskrifte skilder ’n baie eensydige beeld van Moslems as ’n naatloos homogene groep. Baie jong volwassenes neem aktief deel aan gesprekke op digitale media, soos Twitter en Facebook, waar kwessies van kultuur en diversiteit gereeld ter sprake kom. Westerlinge kan baie negatiewe persepsies van Islam en Moslems vorm wanneer hulle oorval word met ’n stortvloed beelde van gruwelikhede wat uitgevoer word deur ekstremistegroepe soos die Islamitiese Staat van Irak en die Ooste (ISIS. Die gevolg is dat alle Moslems gestereotipeer word as fundamentaliste, terroriste en onderdrukkers van vroue. Hierdie kenniskonstruk word gemanipuleer deur die media. ’n Begrip van die redes waarom vroue ’n stuk lap – die kopdoek – dra, kan ’n beginpunt wees vir die verandering van persepsies van Moslems en hul verskillende praktyke. Opvoeders moet oppas om nie net verdraagsaamheid tussen verskillende kulturele groepe te verkondig nie, want verdraagsaamheid impliseer ’n blote bestuur van ’n mens se gevoelens van afsku vir dit wat verdra word. Vrae wat uit ’n standpunt van kritiese geletterdheid gestel kan word aan tekste soos The breadwinner-trilogie deur Deborah Ellis en The girl in the tangerine scarf by Mohja Kahf, word bespreek as voorbeelde wat in die klaskamer gebruik kan word. Hierdie tekste beeld Moslemvroue en -meisies baie anders uit en kan vergelykend gelees word

  18. His Excellency Mr Ian de Jong, Ambassador, Permanent Representative of the Kingdom of the Netherlands to the United Nations Office in Geneva

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Visit of His Excellency Mr Ian de Jong, Ambassador, Permanent Representative of the Kingdom of the Netherlands to the United Nations Office in Geneva, June 2003. From left to right: Dr Albert Ijspeert, Deputy Leader, Magnet and electrical systems Group, Accelerator Technology Division; Mr Maarten Wilbers, Legal Service; Prof. Cecilia Jarlskog, Adviser to the Director-General for Member State Relations; Mr Jan van der Boon, Director of Administration; His Excellency Mr Ian de Jong, Ambassador, Permanent Representative of the Kingdom of the Netherlands to the United Nations Office in Geneva; Prof. Frank Linde, NIKHEF; Dr Lucie Linssen Experimental Physics Division, Technical Assistance Group and Mr C. J. van Riel, Ministry of Education, Culture and Science, Netherlands, Dutch Delegate to Council and Finance Committee.

  19. [KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression].

    Science.gov (United States)

    Marchewka, Zofia; Tacik, Aneta; Piwowar, Agnieszka

    2016-04-18

    On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important role in standard oncology practice. Simultaneous measurement of KIM-1 and NGAL in urine can play a crucial role in carcinogenesis assessment and cancer progression. In the future, they can become rapid diagnostic indicators, which allow one to determine cancer subtype leading to biopsy replacement and therapy improvement. In the present work, beside biochemical characteristics of KIM-1 and NGAL, we will also discuss their role in the diagnosis and assessment of development of cancer.

  20. KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression

    Directory of Open Access Journals (Sweden)

    Zofia Marchewka

    2016-04-01

    Full Text Available On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important role in standard oncology practice. Simultaneous measurement of KIM-1 and NGAL in urine can play a crucial role in carcinogenesis assessment and cancer progression. In the future, they can become rapid diagnostic indicators, which allow one to determine cancer subtype leading to biopsy replacement and therapy improvement. In the present work, beside biochemical characteristics of KIM-1 and NGAL, we will also discuss their role in the diagnosis and assessment of development of cancer.

  1. Bridging communication between public and government: a case study on kim surabaya

    Science.gov (United States)

    Aji, G. G.; Tsuroyya; Dewi, P. A. R.

    2018-01-01

    In democratic era, the public communication paradigm has shifted from a one-way socialization to more interactive one. As a consequence of freedom of speech, the public can Actively communicate with the government and vice versa. The problem is government is almost impossible to reach all public groups. Therefore, they has created the concept of social institutions as a communication hub between the government and its public, named the Kelompok Informasi Masyarakat (KIM). This research examines the activity of KIM in Surabaya on bridging public between government and the public. Using a case study approach, this research utilized various techniques of data collection such as: interviews, observation, and documentation. The results Showed that KIM plays a role in the two-way flow of information; to diseminate program and submit complaints and suggestions from the public about the policy. This study confirm the urgency of utilization on various channels in communicating with the public.

  2. Urinary KIM-1 and AQP-1 in patients with clear renal cell carcinoma: Potential noninvasive biomarkers

    Directory of Open Access Journals (Sweden)

    Mijušković Mirjana

    2016-01-01

    Full Text Available Background/Aim. Kidney injury molecule-1 (KIM-1 and aquaporin-1 (AQP-1 are potential early urinary biomarkers of clear renal cell carcinoma (cRCC. The aim of this study was to ascertain relationship between the urine concentrations KIM-1 and AQP-1 with tumor size, grade, pT stage and type of operation (radical or partial nephrectomy in patients with cRCC. Methods. Urinary concentrations of urinary KIM-1 (uKIM-1 and urinary AQP-1 (uAQP-1 were determined by commercially available ELISA kits. The analysis included 40 patients undergoing partial or radical nephrectomy for cRCC and 40 age- and sex-matched healthy adult volunteers. Results. The median preoperative concentrations of KIM-1 in the cRCC group [0.724 ± 1.120 ng/mg urinary creatinine (Ucr] were significantly greater compared with controls (healthy volunteers (0.210 ± 0.082 ng/mgUcr (p = 0.0227. Postoperatively, uKIM-1 concentration decreased significantly to control values (0.177 ± 0.099 ng/mgUcr vs 0.210 ± 0.082 ng/mgUcr, respectively. The size, grade and stage of tumor were correlated positively with preoperative uKIM-1 concentrations. Contrary to these results, concentrations of uAQP-1 in the cRCC group were significantly lower (0.111 ± 0.092 ng/mgUcr compared with the control group (0.202 ± 0.078 ng/mgUcr (p = 0.0014. Postoperatively, the concentrations of uAQP-1 increased progressively up to control values, approximately. We find no significant correlation between preoperative uAQP-1 concentrations and tumor size, grade and stage. Conclusion. uKIM-1 was found to be a reliable diagnostic marker of cRCC, based on its significantly increased values before and decreased values after the nephrectomy. [Projekat Ministarstva nauke Republike Srbije, br. III41018

  3. Against the Nihilism of Suffering and Death: Richard E. K. Kim and His Works

    Directory of Open Access Journals (Sweden)

    Jooyeon Rhee

    2016-03-01

    Full Text Available This article examines the life and works of Richard E. K. Kim (1932–2009, a first-generation Korean diasporic writer in the United States. It focuses on how Kim struggled to overcome the nihilism of suffering and death that derived from colonialism and the Korean War through his literary works. Kim witnessed firsthand these two major historical events, which caused irrevocable psychological and physical damage to many people of his generation. In his autobiographical fiction, he conveys painful memories of the events by reviving the voices of people in that era. What his works offer us goes beyond vivid memories of the past, however; they also present the power of forgiveness as a condition to overcome the nihilism of suffering and death. Remembrance and forgiveness are, therefore, two major thematic pillars of his works that enable us to connect to these difficult and traumatic times. These themes are portrayed in such a gripping way mainly because Kim tried to maintain a certain distance—an emotional and linguistic distance—from the familiar, in order to elucidate the reality of the human condition: an ontological position of the exile from which he produced his works. This article argues that Kim’s works provide us the possibility to transcend the nihilism of historical trauma through articulating the meaning of remembrance and forgiveness from his self-assumed position of exile.

  4. Non-integrability of the Armbruster-Guckenheimer-Kim quartic Hamiltonian through Morales-Ramis theory

    OpenAIRE

    Acosta-Humánez, P.; Alvarez-Ramírez, M.; Stuchi, T.

    2017-01-01

    We show the non-integrability of the three-parameter Armburster-Guckenheimer-Kim quartic Hamiltonian using Morales-Ramis theory, with the exception of the three already known integrable cases. We use Poincar\\'e sections to illustrate the breakdown of regular motion for some parameter values.

  5. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  6. A Misleading Review of Response Bias: Comment on McGrath, Mitchell, Kim, and Hough (2010)

    Science.gov (United States)

    Rohling, Martin L.; Larrabee, Glenn J.; Greiffenstein, Manfred F.; Ben-Porath, Yossef S.; Lees-Haley, Paul; Green, Paul; Greve, Kevin W.

    2011-01-01

    In the May 2010 issue of "Psychological Bulletin," R. E. McGrath, M. Mitchell, B. H. Kim, and L. Hough published an article entitled "Evidence for Response Bias as a Source of Error Variance in Applied Assessment" (pp. 450-470). They argued that response bias indicators used in a variety of settings typically have insufficient data to support such…

  7. Contactdag Jonge vorsers overzee

    Directory of Open Access Journals (Sweden)

    Royal Academy for Overseas Sciences

    2014-01-01

    Full Text Available Afin d'identifier les principaux aliments d'origine animale consommés par les populations vivant dans la concession 039/11 de la Société de Développement Forestier (SODEFOR, République Démocratique du Congo et de spécifier les déterminants de la consommation, 120 ménages répartis dans 3 villages (Taketa, Ikala 1 et Mombele et la base-vie de Nteno ont été enquêtés pendant 30 jours. Les résultats montrent que la viande de brousse représente 72,00% du nombre de repas, suivi du poisson (24,00% et enfin des produits d'élevage (3,10%. Au total, 30 espèces animales dont 4 légalement interdites de chasse ont été identifiées, pour une biomasse totale de 1235 kg. Les mammifères constituent 97,00% des animaux consommés avec une dominance des artiodactyles (71,60%, des primates (15,40% et des rongeurs (9,10%. Les céphalophes, les cercopithèques et l'athérure sont les plus représentés. Les actes de consommation sont guidés par la disponibilité du produit, le goût et les habitudes alimentaires. La majorité des ménages s'approvisionne auprès d'intermédiaires essentiellement sous forme de morceaux d'animaux. Cette étude suggère un suivi à long terme de la chasse assorti d'une évaluation de l'abondance des espèces animales afin de guider la SODEFOR dans la prise des décisions.

  8. The diagnostic importance of the new marker KIM-1 in kidney damage

    Directory of Open Access Journals (Sweden)

    Zofia Marchewka

    2013-07-01

    Full Text Available In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed.The experimental tests carried out on animals and cell lines derived from the proximal tubule have made possible the detection of genes that are induced early after hypoxia [1].The protein products of these genes can be considered as useful markers for the diagnosis of renal failure. The induction of gene KIM-1 (called Kidney Injury Molecule-1 results in the formation of protein that can be considered as a diagnostic marker.This work describes the data on the structure, biological function and importance of determining the concentrations of KIM-1 in the diagnosis of drug-induced toxicity and kidney damage.

  9. [The diagnostic importance of the new marker KIM-1 in kidney damage].

    Science.gov (United States)

    Marchewka, Zofia; Płonka, Joanna

    2013-07-24

    In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed. The experimental tests carried out on animals and cell lines derived from the proximal tubule have made possible the detection of genes that are induced early after hypoxia. The protein products of these genes can be considered as useful markers for the diagnosis of renal failure. The induction of gene KIM-1 (called Kidney Injury Molecule-1) results in the formation of protein that can be considered as a diagnostic marker. This work describes the data on the structure, biological function and importance of determining the concentrations of KIM-1 in the diagnosis of drug-induced toxicity and kidney damage.

  10. Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus.

    Directory of Open Access Journals (Sweden)

    In O Sun

    Full Text Available The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL and kidney injury molecule-1 (KIM-1 for acute kidney injury (AKI in patients with scrub typhus.From 2014 to 2015, 145 patients were diagnosed with scrub typhus. Of these, we enrolled 138 patients who were followed up until renal recovery or for at least 3 months. We measured serum and urine NGAL and KIM-1 levels and evaluated prognostic factors affecting scrub typhus-associated AKI.Of the 138 patients, 25 had scrub typhus-associated AKI. The incidence of AKI was 18.1%; of which 11.6%, 4.3%, and 2.2% were classified as risk, injury, and failure, respectively, according to RIFLE criteria. Compared with patients in the non-AKI group, patients in the AKI group were older and showed higher total leukocyte counts and hypoalbuminemia or one or more comorbidities such as hypertension (72% vs 33%, p<0.01, diabetes (40% vs 14%, p<0.01, or chronic kidney disease (32% vs 1%, p<0.01. In addition, serum NGAL values (404± 269 vs 116± 78 ng/mL, P<0.001, KIM-1 values (0.80± 0.52 vs 0.33± 0.68 ng/mL, P<0.001, urine NGAL/creatinine values (371± 672 vs 27± 39 ng/mg, P<0.001 and urine KIM-1/creatinine values (4.04± 2.43 vs 2.38± 1.89 ng/mg, P<0.001 were higher in the AKI group than in the non-AKI group. By multivariate logistic regression, serum NGAL and the presence of chronic kidney disease were significant predictors of AKI.Serum NGAL might be an additive predictor for scrub typhus-associated AKI.

  11. North Korea after Kim Chong-il: Leadership Dynamics and Potential Crisis Scenarios

    Science.gov (United States)

    2011-11-01

    legal responsibility, and with specified procedures , the actual process is different.3 To date, regime dynamics in the Kim Chong-il era have been... procedures and regulations provide the outlines of formal rule, the 3 For a detailed examination of how...was also made an alternate member. It is also worth noting that 10 of the 12 members of the NDC were represented in the new Politburo lineup , thus

  12. The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method

    DEFF Research Database (Denmark)

    Keall, Paul J.; Aun Ng, Jin; O'Brien, Ricky

    2015-01-01

    on September 16, 2014. Methods: KIM uses current and prior 2D x-ray images to estimate the 3D target position during cancer radiotherapy treatment delivery. KIM software was written to process kilovoltage (kV) images streamed from a standard C-arm linear accelerator with a gantry-mounted kV x-ray imaging...... system. A 120° pretreatment kV imaging arc was acquired to build the patient-specific 2D to 3D motion correlation. The kV imager was activated during the megavoltage (MV) treatment, a dual arc VMAT prostate treatment, to estimate the 3D prostate position in real-time. All necessary ethics, legal......, and regulatory requirements were met for this clinical study. The quality assurance processes were completed and peer reviewed. Results: During treatment, a prostate position offset of nearly 3 mm in the posterior direction was observed with KIM. This position offset did not trigger a gating event. After...

  13. Ab initio and Gordon--Kim intermolecular potentials for two nitrogen molecules

    International Nuclear Information System (INIS)

    Ree, F.H.; Winter, N.W.

    1980-01-01

    Both ab initio MO--LCAO--SCF and the electron-gas (or Gordon--Kim) methods have been used to compute the intermolecular potential (Phi) of N 2 molecules for seven different N 2 --N 2 orientations. The ab initio calculations were carried out using a [4s3p] contracted Gaussian basis set with and without 3d polarization functions. The larger basis set provides adequate results for Phi>0.002 hartree or intermolecular separations less than 6.5--7 bohr. We use a convenient analytic expression to represent the ab initio data in terms of the intermolecular distance and three angles defining the orientations of the two N 2 molecules. The Gordon--Kim method with Rae's self-exchange correction yields Phi, which agrees reasonably well over a large repulsive range. However, a detailed comparison of the electron kinetic energy contributions shows a large difference between the ab initio and the Gordon--Kim calculations. Using the ab initio data we derive an atom--atom potential of the two N 2 molecules. Although this expression does not accurately fit the data at some orientations, its spherical average agrees with the corresponding average of the ab initio Phi remarkably well. The spherically averaged ab initio Phi is also compared with the corresponding quantities derived from experimental considerations. The approach of the ab initio Phi to the classical quadrupole--quadrupole interaction at large intermolecular separation is also discussed

  14. Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis.

    Science.gov (United States)

    Noyan, Aytul; Parmaksiz, Gonul; Dursun, Hasan; Ezer, Semire Serin; Anarat, Ruksan; Cengiz, Nurcan

    2015-10-01

    The clinical tests currently in use for obstructive nephropathy (such as renal ultrasonography, differential radionuclide renal scans and urinary creatinine concentration data) are not efficient predictors of the subsequent clinical course. Novel and simple biomarkers are required which, if proven, could be clinically beneficial in determining if a patient is eligible for surgery or reno-protective therapy. More recently, the interest of clinicians has focused on the potential of urinary neutrophil gelatinase-associated lipocalin (uNGAL), urinary kidney injury molecule-1 (uKIM-1) and urinary liver-type fatty acid-binding proteins (uL-FABP) as biomarkers for renal function in children with hydronephrosis (HN). The purpose of this study was to investigate possible clinical applications of uNGAL, uKIM-1 and uL-FABP as beneficial non-invasive biomarkers to determine whether or not surgical intervention is required in children with HN. Renal ultrasonography and radionuclide renal scans were used as diagnostic tools to detect HN. Patients were divided into two groups based on the antero-posterior diameter of their renal pelvis and the presence of dysfunction. Group 1 included 26 children with severe HN (with dysfunction), and group 2 consisted of 36 children with mild HN (without dysfunction). Urine samples were collected from 62 children with HN and 20 healthy children. Hydronephrosis was more common in males than in females, with a male to female ratio of 9:1 in the study sample. The incidence of left kidney involvement (32 patients) was slightly higher than right kidney involvement (28 patients). Compared with controls and group 2, the ratio of uNGAL to creatinine was significantly higher in group 1 (p hydronephrosis and dysfunction had significantly increased uNGAL, and uNGAL/Cr concentrations. However, uKIM-1, uKIM-1/Cr, uL-FABP and uL-FABP/Cr concentrations were not significantly different when compared with controls. These results support the use of u

  15. Kimi mantlipärija sai mõjukatele ametipostidele / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2010-01-01

    Põhja-Korea pealinnas toimunud Tööliste Partei kongressil määrati riigi liidri Kim Jong-ili noorim poeg Kim Jong-un kesksõjakomisjoni aseesimeheks ja keskkomitee liikmeks. Poliitbüroosse määrati alternatiivliikmena Kim Jong-ili õe abikaasa Chang Song-taek

  16. Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus.

    Science.gov (United States)

    Sun, In O; Shin, Sung Hye; Cho, A Young; Yoon, Hyun Ju; Chang, Mi Yok; Lee, Kwang Young

    2017-01-01

    The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) for acute kidney injury (AKI) in patients with scrub typhus. From 2014 to 2015, 145 patients were diagnosed with scrub typhus. Of these, we enrolled 138 patients who were followed up until renal recovery or for at least 3 months. We measured serum and urine NGAL and KIM-1 levels and evaluated prognostic factors affecting scrub typhus-associated AKI. Of the 138 patients, 25 had scrub typhus-associated AKI. The incidence of AKI was 18.1%; of which 11.6%, 4.3%, and 2.2% were classified as risk, injury, and failure, respectively, according to RIFLE criteria. Compared with patients in the non-AKI group, patients in the AKI group were older and showed higher total leukocyte counts and hypoalbuminemia or one or more comorbidities such as hypertension (72% vs 33%, pscrub typhus-associated AKI.

  17. Children on Social Media, Twiter and Facebook (profile of Beyonce and Kim Kardashian

    Directory of Open Access Journals (Sweden)

    Anamarija Bilan

    2017-09-01

    Full Text Available Publishing children’s photos in the media violates their privacy right, which is protected, guaranteed and regulated by numerous international and Croatian laws and regulations. Likewise, publishing photos of children on social network profiles, such as Facebook or Twitter, violates the right to privacy. In this paper it will be researched the extent to which children’s photos are being disclosed and their privacy is being undermined in case of two Facebook and two Twitter profiles - Beyonce Knowles and Kim Kardashian. It will also research whether children are used for business purposes, whether they are advertising some of their products or shows, and so on, with the photographs of children. The content analysis methodology analyzed the Facebook and Twitter profiles of two respondents in the period from January 1 to February 22, 2016, during which they published a total of 459 posts on profiles of both networks. The analysis found that the total number of “posts” shows a small number of photographs of children but also that those published by Kim Kardashian are often used to promote or promote some of the products or programs, which violates the privacy of children and increases the number “like”.

  18. Moral is political Notions of ideal citizenship in Lie Kim Hok’s Hikajat Khonghoetjoe

    Directory of Open Access Journals (Sweden)

    Evi Sutrisno

    2017-04-01

    Full Text Available This paper argues that the Hikajat Khonghoetjoe (The life story of Confucius, written by Lie Kim Hok in 1897, is a medium to propose modern ideas of flexible subjectivity, cosmopolitanism, active citizenship and the concepts of good governance to the Chinese Peranakans who experienced political and racial discrimination under Dutch colonization. Using the figure of Confucius, Lie aimed to cultivate virtuous subjects who apply their faith and morality in political sphere. He intended to raise political awareness and rights among the Chinese as colonial subjects and to valorize their bargaining power with the Dutch colonial government. By introducing Confucianism, Lie proposed that the Chinese reconnect themselves with China as an alternative patronage which could subvert White supremacy. Instead of using sources in Chinese, Lie translated the biography of Confucius from the European texts. In crafting his story, Lie applied conglomerate authorship, a technique commonly practised by Malay authors. It allowed him to select, combine and appropriate the source texts. To justify that Confucius' virtue and his teaching were superb and are applicable to contemporary life, Lie borrowed and emphasized European writers’ high appraisal of Confucianism, instead of using his own arguments and opinions. I call this writing technique “indirect agency”.

  19. "Sundiata, Lion King of Mali." Adapted by Kim Hines, Featuring Griot Alhaji Papa Susso, Cue Sheet for Students.

    Science.gov (United States)

    Freeman, Aakhu TuahNera

    This performance guide is designed for teachers to use with students before and after a performance of "Sundiata: Lion King of Mali," adapted by Kim Hines and featuring Griot Alhaji Papa Susso. The guide, called a "Cuesheet," contains seven activity sheets for use in class, addressing: (1) Sundiata: Man & Myth (discusses…

  20. Kim Wŏn-haeng’s Intellectual Influences on Hong Tae-yong: The Case of Relations between

    Directory of Open Access Journals (Sweden)

    Login Lok-yin Law

    2015-08-01

    Full Text Available In the 18th century Chosŏn (1392-1910, some scholars, such as Hong Tae-yong (1731-1783 advocated that Chosŏn should learn the advantages of the Qing (1644-1912 society to reform the social structure and government of Chosŏn. The school of these advocates has been known as Pukhak by historians. The intellectual factors of the school of Pukhak’s formation and development have been overlooked by the academia of Chosŏn intellectual history. In fact, Pukhak was closely related to the idea of the school of Nakhak which believed that nature of things was equivalent to humans. Kim Wŏn-haeng, was one of the supporters of Nakhak and Hong Tae-yong was one of the students of Kim. Hong’s thought and writing exposed that his thought was profoundly influenced by Kim Wŏn-haeng. Hong was deemed to be the first prominent scholar of the Pukhak School during the 18th century Chosŏn. Hong and other scholars of Pukhak advocated learning the new knowledge from Qing China even though it was a barbarian society. Therefore, this paper will investigate the intellectual relationships between Hong Tae-yong and Kim Wŏn-haeng to reveal how intellectuals of Nakhak shaped the formation of Pukhak School and exposed the idea of learning from Qing China.

  1. Language and Family Dispersion: North Korean Linguist Kim Su-gyŏng and the Korean War

    Directory of Open Access Journals (Sweden)

    Ryuta Itagaki

    2017-03-01

    Full Text Available This article analyzes the unpublished memoir of Kim Su-gyŏng (1918–2000, a linguist who was active in North Korea from the mid-1940s until the late 1960s, and situates his account of his experience of the Korean War within the context of his linguistic essays and correspondence. In doing so, the article considers the role that the personal and the social play in language, utilizing Saussure’s theoretical framework, with which Kim himself was well versed. Kim wrote his memoirs in the 1990s to his family, from whom he had become separated during the Korean War and who now lived in Toronto. In this text, he writes in “personal” language that reveals his uncertainty and his feelings for his family, but then immediately negates these feelings through the use of “social” language, which resonates with his interpretation of the linguistic thesis that Josef Stalin developed during the Korean War on language and national identity. For Kim, the relationship between language and nation was not at all self-evident, but something that he idealized in response to the dispersal of his family. By offering a reflexive reading of a memoir written by a North Korean linguist, this article makes a breakthrough in the investigation of North Korean wartime academic history, which has not risen above the level of analyzing articles in the field of linguistics that were published at the time.

  2. A STUDY OF METABOLIC SYNDROME IN PATIENTS UNDERGOING CORONARY ANGIOGRAPHY AT KIMS HOSPITAL, HUBBALLI, KARNATAKA, INDIA

    Directory of Open Access Journals (Sweden)

    Chandrashekar K

    2018-01-01

    Full Text Available BACKGROUND Coronary heart disease has become an epidemic since 20th century. Deaths due to the same are increasing of around 17.5 million deaths in year 2012. The deaths are increasing more in developing countries and metabolic syndrome is a cluster of disorders, which are promoting the development of coronary artery diseases. The disorders include central obesity, insulin resistance, dyslipidaemia and hypertension. Increasing prevalence, changing lifestyle and progression of the disease without obvious symptoms had led to increasing morbidity and mortality. The non-infectious epidemic of the century is posing great challenges to healthcare and research in development of more infrastructure and funds to prevent and treat the disease. MATERIALS AND METHODS A total of 100 patients diagnosed with CAD and posted for Coronary Angiogram (CAG in ICCU at KIMS Hospital, Hubballi, were studied over a period of one and a half year. Cases were categorised according to ATPIII and new IDF criteria for metabolic syndrome and compared. Clinical evaluation, ECG, lipid profile and 2D-echo was done. Statistical analysis done using unpaired t-test, Mann-Whitney tests, Chi-square test and Kappa statistics. RESULTS Of the total 100, 57 had metabolic syndrome by either ATP criteria or IDF criteria. Kappa=0.859 (p-value 150 mg/dL and DM or FBS >100 mg/dL (p value <0.001. The mean values of SBP (144.0 vs. 120.8, DBP (85.6 vs. 73.8 and waist circumference (95.4 vs. 87.7 was statistically significant (p value <0.01 between patients with metabolic syndrome and without metabolic syndrome with IDF criteria (p value <0.001. It was observed LAD (28.1% was the most common vessel involved individually. There was no much significance related to metabolic syndrome. Incidence of CAD was more common in patients with metabolic syndrome than other group. CONCLUSION The prevalence of metabolic syndrome was high in patients with CAD. Both metabolic syndrome definitions identify subset

  3. Report on visit from Prof. Kim Lutzen: Friday, 6 November 1998, Korolinska Institute (dept of nursing Stockholm, Sweden

    Directory of Open Access Journals (Sweden)

    Kim Lutzen

    1999-10-01

    Full Text Available Prof. Kim Lutzen contacted the Department of Advanced Nursing Sciences, Unisa, via the Department's Web Page. Prof. Lutzen is the Chair of the Department of Nursing, which offers undergraduate, master and doctoral programmes. This Department of Nursing is situated within the Karolinska Institute, which comprises 29 Departments of Health Sciences, including a number of Medical Departments, Dentistry, Occupational Therapy, Physiotherapy, and Nursing. Prof. Lutzen emphasised that there is no Swedish phrase similar to "nursing science", consequently this t e n seems to be somewhat unfamiliar to the Swedish nurses. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  4. The complete larval development of Eurypanopeus canalensis Abele and Kim, 1989 (Crustacea: Brachyura: Panopeidae described from laboratory reared material

    Directory of Open Access Journals (Sweden)

    Marcelo U. García-Guerrero

    2005-09-01

    Full Text Available The estuarine panopeid crab Eurypanopeus canalensis Abele and Kim, 1989, is an eastern tropical Pacific species with a known distribution from the southeastern Gulf of California, Mexico, to Panama. Its complete larval development is fully described and illustrated from laboratory-reared material. The four zoeal stages and the megalopa are compared with two congeneric species from the West Atlantic, E. abbreviatus (Stimpson, 1860 and E. depressus (Smith, 1869. The main differences between larvae of E. canalensis and those of these two species include telson setation and the presence/absence of a stout hook-like spine in the megalopae cheliped ischium.

  5. An Inquiry of Intentions in Kim Hye-yong's 'First Meeting': A North Korean Short Story in Korea Today (2007).

    OpenAIRE

    Alzo David-West

    2013-01-01

    This paper examines the problem of the intentional fallacy in the North Korean short story 'First Meeting' by Kim Hye-yong. Serially published in Korea Today in 2007, the nationalist allegory centres on Shin Ch'ong-mi, a young female journalist in Pyongyang, who falls in love with her penfriend Song-u, a soldier in the Korean People's Army, and struggles to remain devoted to him when he suddenly stops writing. With the literary-critical method of counterintuitive reading, the inquiry analyses...

  6. Teasing out the compressed education debates in contemporary South Korea: Media portrayal of figure skater Yuna Kim

    OpenAIRE

    Kim, Hye Jin

    2013-01-01

    In this thesis, I argue that the heated debates about South Korea’s education policy consist of problems that arise from different genres of discourses that in turn belong to different historical moments and education values. I engage in a media discourse analysis of the reportage on South Korean international sport celebrity Yuna Kim that highlight the key education debates currently taking place in South Korea. First, I deal with the neologism umchinttal (my mom’s friend’s daughter) as an i...

  7. The Expression of the Femininity and Imperialism : Through comparison study of works of Toshiko Tamura and Myung-soon Kim

    OpenAIRE

    金, 玟妵

    2005-01-01

    Toshiko Tamura and Myung-soon Kim flourished in 1910-20 in Japan and Korea. In those days it was an act of a man to write. The feminine was demanded above all to the thing which a woman wrote by the literary world and the society, so that woman does not invade a domain of a man. A lot of studies about that the motherhood is one of a model of feminine, it was used to mobilize a woman for war, while militarism advances. Then is what kind of position was there the femininity at socially and cult...

  8. New Nordic Exceptionalism: Jeuno JE Kim and Ewa Einhorn's The United Nations of Norden and other realist utopias

    Directory of Open Access Journals (Sweden)

    Mathias Danbolt

    2016-11-01

    Full Text Available At the 2009 Nordic Culture Forum summit in Berlin that centered on the profiling and branding of the Nordic region in a globalized world, one presenter stood out from the crowd. The lobbyist Annika Sigurdardottir delivered a speech that called for the establishment of “The United Nations of Norden”: A Nordic union that would gather the nations and restore Norden's role as the “moral superpower of the world.” Sigurdardottir's presentation generated such a heated debate that the organizers had to intervene and reveal that the speech was a performance made by the artists Jeuno JE Kim and Ewa Einhorn. This article takes Kim and Einhorn's intervention as a starting point for a critical discussion of the history and politics of Nordic image-building. The article suggests that the reason Kim and Einhorn's speech passed as a serious proposal was due to its meticulous mimicking of two discursive formations that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn's United Nations of Norden (UNN-performance, the article examines the historical development and ideological underpinnings of the image of Nordic unity at play in the discourses of Nordic exceptionalism and the New Nordic. By focusing on how the UNN-project puts pressure on the role of utopian imaginaries in the construction of Nordic self-images, the article describes the emergence of a discursive framework of New Nordic Exceptionalism.

  9. Validation Study of Kim's Sham Needle by Measuring Facial Temperature: An N-of-1 Randomized Double-Blind Placebo-Controlled Clinical Trial

    Directory of Open Access Journals (Sweden)

    Sanghun Lee

    2012-01-01

    Full Text Available Introduction. In 2008, Kim's sham needle was developed to improve the quality of double-blinded studies. The aim of this study is to validate Kim's sham needle by measuring facial temperature. Methods. We designed “N-of-1” trials involving 7 smokers. One session was composed of 2 stimulations separated by a 2 h washout period. Six sessions were applied daily for all subjects. Infrared thermal imaging was used to examine the effects of acupuncture (HT8, KI2 on facial temperature following smoking-induced decrease. Results. All subjects demonstrated decreased temperatures after sham needle treatment, but 5 of the 7 subjects showed increased temperatures after real needle treatment. 6 of the 7 subjects showed a significant difference (P<0.05 between treatments with real and sham needles. Thus, the physiological stimulation of Kim's sham needle is different from that of a real needle, suggesting that Kim's sham needle is a potential inactive control intervention.

  10. Muusikauudised : Lu : k ja Jäääär koos laval. Britney Spears tegutseb. Lenny Kravitz ja Mick Jagger. Kim Wilde

    Index Scriptorium Estoniae

    2001-01-01

    Tartus Sõbra majas toimunud kontserdist. Videost "Britney: The video". Heliplaatidest: "Britney", "The Best of Pink Floyd", "Lenny", Mick Jagger "Goddess In The Doorway", "The Very Best Of Kim Wilde"

  11. Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis.

    Science.gov (United States)

    Nozaki, Yuji; Nikolic-Paterson, David J; Snelgrove, Sarah L; Akiba, Hisaya; Yagita, Hideo; Holdsworth, Stephen R; Kitching, A Richard

    2012-05-01

    The T-cell immunoglobulin mucin 1 (Tim-1) modulates CD4(+) T-cell responses and is also expressed by damaged proximal tubules in the kidney where it is known as kidney injury molecule-1 (Kim-1). We sought to define the role of endogenous Tim-1 in experimental T-cell-mediated glomerulonephritis induced by sheep anti-mouse glomerular basement membrane globulin acting as a planted foreign antigen. Tim-1 is expressed by infiltrating activated CD4(+) cells in this model, and we studied the effects of an inhibitory anti-Tim-1 antibody (RMT1-10) on immune responses and glomerular disease. Crescentic glomerulonephritis, proliferative injury, and leukocyte accumulation were attenuated following treatment with anti-Tim-1 antibodies, but interstitial foxp3(+) cell accumulation and interleukin-10 mRNA were increased. T-cell proliferation and apoptosis decreased in the immune system along with a selective reduction in Th1 and Th17 cellular responses both in the immune system and within the kidney. The urinary excretion and renal expression of Kim-1 was reduced by anti-Tim-1 antibodies reflecting diminished interstitial injury. The effects of anti-Tim-1 antibodies were not apparent in the early phase of renal injury, when the immune response to sheep globulin was developing. Thus, endogenous Tim-1 promotes Th1 and Th17 nephritogenic immune responses and its neutralization reduces renal injury while limiting inflammation in cell-mediated glomerulonephritis.

  12. Viscous flux flow velocity and stress distribution in the Kim model of a long rectangular slab superconductor

    Science.gov (United States)

    Yang, Yong; Chai, Xueguang

    2018-05-01

    When a bulk superconductor endures the magnetization process, enormous mechanical stresses are imposed on the bulk, which often leads to cracking. In the present work, we aim to resolve the viscous flux flow velocity υ 0/w, i.e. υ 0 (because w is a constant) and the stress distribution in a long rectangular slab superconductor for the decreasing external magnetic field (B a ) after zero-field cooling (ZFC) and field cooling (FC) using the Kim model and viscous flux flow equation simultaneously. The viscous flux flow velocity υ 0/w and the magnetic field B* at which the body forces point away in all of the slab volumes during B a reduction, are determined by both B a and the decreasing rate (db a /dt) of the external magnetic field normalized by the full penetration field B p . In previous studies, υ 0/w obtained by the Bean model with viscous flux flow is only determined by db a /dt, and the field B* that is derived only from the Kim model is a positive constant when the maximum external magnetic field is chosen. This means that the findings in this paper have more physical contents than the previous results. The field B* stress changing with decreasing field B a after ZFC if B* ≤ 0. The effect of db a /dt on the stress is significant in the cases of both ZFC and FC.

  13. Helen Kim as New Woman and Collaborator: A Comprehensive Assessment of Korean Collaboration under Japanese Colonial Rule

    Directory of Open Access Journals (Sweden)

    AhRan Ellie Bae

    2017-02-01

    Full Text Available Although almost seventy years has passed since Korea's liberation from Japanese rule, the issue of collaboration still haunts Korea today. Attempts to resolve this issue have tended to focus attention on the traitorous actions of "collaborators" without considering the gray areas that surround their actions such as the circumstances that influenced the accused to commit their alleged traitorous acts and the intentions that drove their decisions. Helen Kim, as a "new woman" and an educator, valued the necessity of providing education for women. Yet, her efforts to realize this goal, to the contrary, forced her into actions that would later be used to construct a reputation as a Japanese collaborator. Korea's nationalist historiography has a tendency to polarize this issue by categorizing a "collaborator" as either a traitor or a patriot. However, when we take a closer look at these collaborators' lives, we discover that most collaboration happened in gray areas where it is often difficult to clearly draw a line between treason and collaboration. Helen Kim's case suggests that the issue of collaboration cannot be fully explained by nationalist historiography's framework and we must give attention to these gray areas. Through her story I hope to complicate the issue of collaboration by raising questions that address the gray areas that surround the actions of "collaborators." In doing so, I hope to challenge the nationalist historiography's propensity to oversimplify this issue and present a more nuanced understanding of it.

  14. An Inquiry of Intentions in Kim Hye-yong's 'First Meeting': A North Korean Short Story in Korea Today (2007.

    Directory of Open Access Journals (Sweden)

    Alzo David-West

    2013-11-01

    Full Text Available This paper examines the problem of the intentional fallacy in the North Korean short story 'First Meeting' by Kim Hye-yong. Serially published in Korea Today in 2007, the nationalist allegory centres on Shin Ch'ong-mi, a young female journalist in Pyongyang, who falls in love with her penfriend Song-u, a soldier in the Korean People's Army, and struggles to remain devoted to him when he suddenly stops writing. With the literary-critical method of counterintuitive reading, the inquiry analyses the structural relations of the narrative, its discourse on desire, its apparent intentions, and its contravening elements, revealing an incidental unstable narrative that is symbolically protesting of the moral of the story to affectionately embrace the political authority of the North Korean party-army regime in the military-first (songun era.

  15. Cooling Simulation and Thermal Abuse Modeling of Lithium-Ion Batteries Using the Newman, Tiedemann, Gu, and Kim (NTGK) Model

    DEFF Research Database (Denmark)

    Saeed Madani, Seyed; Swierczynski, Maciej Jozef; Kær, Søren Knudsen

    2017-01-01

    This paper gives insight into the cooling simulation and thermal abuse modeling of lithium-ion batteries by ANSYS FLUENT. Cooling strategies are important issues in the thermal management of lithium-ion battery systems, and it is essential to investigate them attentively in order to maintain...... the functioning temperature of batteries within an optimum range. The high temperature is able not only to decrease the efficiency of batteries but also may lead to the thermal runaway. To comprehend further, the thermal abuse behavior of lithium-ion batteries based on The Newman, Tiedemann, Gu, and Kim (NTGK......) model has been implemented in ANSYS FLUENT software. The results show that to achieve an optimum energy consumption for battery cooling, a minimum value of average heat transfer coefficient can be selected in order to keep the functioning temperature of batteries within an optimum range....

  16. Urinary KIM-1, NGAL and L-FABP for the diagnosis of AKI in patients with acute coronary syndrome or heart failure undergoing coronary angiography.

    Science.gov (United States)

    Torregrosa, Isidro; Montoliu, Carmina; Urios, Amparo; Andrés-Costa, María Jesús; Giménez-Garzó, Carla; Juan, Isabel; Puchades, María Jesús; Blasco, María Luisa; Carratalá, Arturo; Sanjuán, Rafael; Miguel, Alfonso

    2015-11-01

    Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type fatty acid-binding protein (uL-FABP) for early detection of AKI in these patients, comparing their performance with another group of cardiac surgery patients. Biomarkers were measured in 193 patients, 12 h after intervention. In the ROC analysis, AUC for KIM-1, NGAL and L-FABP was 0.713, 0.958 and 0.642, respectively, in the coronary angiography group, and 0.716, 0.916 and 0.743 in the cardiac surgery group. Urinary KIM-1 12 h after intervention is predictive of AKI in adult patients undergoing coronary angiography, but NGAL shows higher sensitivity and specificity. L-FABP provides inferior discrimination for AKI than KIM-1 or NGAL in contrast to its performance after cardiac surgery. This is the first study showing the predictive capacity of KIM-1 for AKI after coronary angiography. Further studies are still needed to answer relevant questions about the clinical utility of biomarkers for AKI in different clinical settings.

  17. Pyongyangi leedi Macbeth tõmbab niite Põhja-Koreas / Yuriko Koike

    Index Scriptorium Estoniae

    Koike, Yuriko

    2010-01-01

    Põhja-Korea liidri Kim Jong-il'i õest Kim Kyong-hui'st. Autori, Jaapani endise kaitseministri väitel on hakatud uskuma, et Kim Jong-il võib igal hetkel määrata just Kim Kyong-hui üleminekuaja valitsejaks, kes peab korraldama tema surma järel kolmanda põlvkonna Kimi võimuletuleku, kuid Kim Kyong-hui võib ise ihata saada Kim Jong-ili mantlipärijaks

  18. Procjena citomorfologije, HPV statusa i HPV 16 genotipa u predikciji ishoda bolesti kod pacijentica s citološkim nalazom ASCUS i LSIL

    OpenAIRE

    Vrdoljak-Mozetič, Danijela; Štemberger-Papić, Snježana; Verša Ostojić, Damjana; Rubeša-Mihaljević, Roberta; Dinter, Morana; Brnčić-Fischer, Alemka; Krašević, Maja

    2016-01-01

    Cilj: Istražiti međusobnu povezanost i prognostički značaj HPV statusa (humani papiloma-virus), HPV 16 genotipa i citomorfologije kod pacijentica s citološkim nalazom abnormalnih stanica pločastog epitela vrata maternice graničnog i blagog stupnja. Materijali i metode: U studiju su uključene pacijentice s inicijalnim citološkim nalazom vrata maternice atipičnih skvamoznih stanica neodređenog značenja (ASCUS, N = 160) i skvamozne intraepitelne lezije niskog stupnja (LSIL, N = 155). Analizirane...

  19. Chun Doo Hwan's Manipulation of the Kwangju Popular Uprising

    National Research Council Canada - National Science Library

    Sohn, Donald

    1998-01-01

    Many scholars and journalists point to the tragic events that occurred in the Kwangju Popular Uprising as a pronounced materialization of the dependent nature of the relationship between U.S. and South Korea...

  20. KIM, Steady-State Transport for Fixed Source in 2-D Thermal Reactor by Monte-Carlo

    International Nuclear Information System (INIS)

    Cupini, E.; De Matteis, A.; Simonini, R.

    1980-01-01

    1 - Description of problem or function: KIM (K-infinite Monte Carlo) is a program which solves the steady-state linear transport equation for a fixed-source problem (or, by successive fixed-source runs, for the eigenvalue problem) in a two-dimensional infinite thermal reactor lattice. The main quantities computed in some broad energy groups are the following: - Fluxes and cross sections averaged over the region (i.e. a space portion that can be unconnected but contains everywhere the same homogeneous material), grouping of regions, the whole element. - Average absorption and fission rates per nuclide. - Average flux, absorption and production distributions versus energy. 2 - Method of solution: Monte Carlo simulation is used by tracing particle histories from fission birth down through the resonance region until absorption in the thermal range. The program is organised in three sections for fast, epithermal and thermal simulation, respectively; each section implements a particular model for both numerical techniques and cross section representation (energy groups in the fast section, groups or resonance parameters in the epithermal section, points in the thermal section). During slowing down (energy above 1 eV) nuclei are considered as stationary, with the exception of some resonance nuclei whose spacing between resonances is much greater than the resonance width. The Doppler broadening of s-wave resonances of these nuclides is taken into account by computing cross sections at the current neutron energy and at the temperature of the nucleus hit. During thermalization (energy below 1 eV) the thermal motion of some nuclides is also considered, by exploiting scattering kernels provided by the library for light water, heavy water and oxygen at several temperatures. KIM includes splitting and Russian roulette. A characteristic feature of the program is its approach to the lattice geometry. In fact, besides the usual continuous treatment of the geometry using the well

  1. Kim Magrini | NREL

    Science.gov (United States)

    System Control software Education Ph.D., Physical Chemistry, University of Colorado at Boulder, 1984-1989 But Converges During Decomposition-Transformation," Soil Biology and Biochemistry (2013) " Catalytic Conditioning of Biomass-Derived Syngas," Topics in Catalysis (2012) "Transformation of

  2. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time

    NARCIS (Netherlands)

    Kramer, Andrea B.; van Timmeren, Mirjan M.; Schuurs, Theo A.; Vaidya, Vishal S.; Bonventre, Joseph V.; van Goor, Harry; Navis, Gerjan

    Kramer AB, van Timmeren MM, Schuurs TA, Vaidya VS, Bonventre JV, van Goor H, Navis G. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol 296: F1136-F1145, 2009. First published February

  3. Evaluation of a commercially available ELISA kit for quantifying imidacloprid residues in Erthrina sandwicensis leaves for management of the Erythrina gall wasp, Quadrastichus erythrinae Kim.

    Science.gov (United States)

    Joseph Fischer; Brian Strom; Sheri Smith

    2009-01-01

    The erythrina gall wasp (EGW), Quadrastichus erythrinae Kim 2004, was first detected in Hawaii in 2005 and has been infesting and killing Erythrina trees throughout the island chain since. It is believed EGW originated from Africa (Messing et al. 2009). Its host range appears to be limited to Erythrina; its...

  4. The trouble with halos: invited commentary on Kim, S., & Harris, P. L. (2014). Children prefer to learn from mind-readers. British Journal of Developmental Psychology.

    Science.gov (United States)

    Richert, Rebekah A

    2014-11-01

    This commentary on Kim and Harris (2014) addresses the authors' interpretation of the halo effect, in which 5- to 6-year-old children preferentially agreed with an informant who could read other people's minds, regardless of domain of knowledge. © 2014 The British Psychological Society.

  5. Understanding internal backgrounds in NaI(Tl) crystals toward a 200 kg array for the KIMS-NaI experiment

    Energy Technology Data Exchange (ETDEWEB)

    Adhikari, P.; Adhikari, G.; Oh, S.Y. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Choi, S.; Joo, H.W.; Kim, K.W.; Kim, S.K. [Seoul National University, Department of Physics and Astronomy, Seoul (Korea, Republic of); Ha, C.; Jeon, E.J.; Kang, W.G.; Kim, H.O.; Kim, N.Y.; Lee, H.S.; Lee, J.H.; Lee, M.H.; Leonard, D.S.; Li, J.; Olsen, S.L.; Park, H.K.; Park, K.S.; So, J.H.; Yoon, Y.S. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Hahn, I.S. [Ewha Womans University, Department of Science Education, Seoul (Korea, Republic of); Kim, H.J. [Kyungpook National University, Department of Physics, Daegu (Korea, Republic of); Kim, Y.D. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Kim, Y.H. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Park, H.S. [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2016-04-15

    The Korea Invisible Mass Search (KIMS) collaboration has developed low-background NaI(Tl) crystals that are suitable for the direct detection of WIMP dark matter. Building on experience accumulated during the KIMS-CsI programs, the KIMS-NaI experiment will consist of a 200 kg NaI(Tl) crystal array surrounded by layers of shielding structures and will be operated at the Yangyang underground laboratory. The goal is to provide an unambiguous test of the DAMA/LIBRA annual modulation signature. Measurements of six prototype crystals show progress in the reduction of internal contamination from radioisotopes. Based on our understanding of these measurements, we expect to achieve a background level in the final detector configuration that is less than 1 count/day/keV/kg for recoil energies around 2 keV. The annual modulation sensitivity for the KIMS-NaI experiment shows that an unambiguous 7σ test of the DAMA/LIBRA signature would be possible with a 600 kg year exposure with this system. (orig.)

  6. Anthropocene Knowledge Practices in McKenzie Wark’s Molecular Red and Kim Stanley Robinson’s Aurora

    Directory of Open Access Journals (Sweden)

    Gib Prettyman

    2018-02-01

    Full Text Available Through a close reading of McKenzie Wark’s theoretical treatise 'Molecular Red' (2015 and Kim Stanley Robinson’s novel 'Aurora' (2015, this essay examines how Anthropocene knowledge practices challenge our conceptions of human agency in provocative and potentially productive ways. For example, our knowledge of climate science arises through global material infrastructures. As material components of Anthropocene knowledge practices, these infrastructures reveal the material labors and cyborg structures by means of which our knowledge is produced. Wark sees the heterogenous materiality of Anthropocene knowledge practices as evidence for the value of ‘low theories’ based on a ‘labor point of view.’ At the same time, Anthropocene knowledge practices reveal ‘eco-logical’ complexities and fundamental recognitions of the ‘intra-action’ of entangled matter. These complexities produce very estranged views of human agency. Robinson’s novel highlights the eco-logical implications of contemporary knowledge practices by imagining an interstellar ship that must function as a completely artificial ecosystem for a 170-year voyage to another solar system. The significance of knowledge practices and eco-logical complexity is most evident when failures or crises arise, and 'Aurora' tells the story of many such failures. However, I argue that Robinson’s novel and Wark’s ‘low theory’ ultimately function as hopeful accounts of Anthropocene knowledge practices. Among other things, these practices show the material importance of storytelling and point the way toward more complexly realist theories of human agency.

  7. Concept development of "compassion fatigue" in clinical nurses: Application of Schwartz-Barcott and Kim's hybrid model

    Directory of Open Access Journals (Sweden)

    Mahdieh Sabery

    2017-06-01

    Full Text Available Compassion fatigue is not a new concept in nursing; yet, it is not well known and there is no fixed clear definition of the term. The ambiguity surrounding how to define compassion fatigue has challenged its measurement and evaluation. Thus, any attempt to determine attributes of this underdeveloped concept and studying it in a new socio-cultural context requires concept development. The purpose of this study is to clarify the concept of compassion fatigue through concept development and to produce a vivid and tentative definition of this concept in clinical practice. Concept development was conducted using a three-step hybrid concept analysis including theoretical, fieldwork, and final analysis phases according to Schwartz-Barcott and Kim's method. We reviewed and analyzed 48 articles that met the inclusion criteria. Following, the first author conducted 13 interviews with clinical nurses followed by an inductive content analysis. Finally, a comprehensive definition of compassion fatigue in nurses was attained. Compassion fatigue in nurses can be explained as a cumulative and progressive process of absorption of the patient’s pain and suffering formed from the sympathetic and caring interactions with the patients and their families. The physical, emotional, intellectual, spiritual, social, and organizational consequences of compassion fatigue are so extensive that they threaten the existential integrity of the nurse. Context-based variables (culture, family, and community such as personality features like devotion behaviors and commitment towards the patient, exposure to multiple stressors, organizational challenges, and lack of self-care are factors associated with an increased risk of compassion fatigue. Concept development of compassion fatigue is the first step in the protection of nurses against the destructive consequences of compassion fatigue and to improve quality of care.

  8. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka.

    Science.gov (United States)

    De Silva, Pallagae Mangala C S; Mohammed Abdul, Khaja Shameem; Eakanayake, Eakanayake M D V; Jayasinghe, Sudheera Sammanthi; Jayasumana, Channa; Asanthi, Hewa Bandulage; Perera, Hettiarachigae S D; Chaminda, Gamage G Tushara; Chandana, Ediriweera P S; Siribaddana, Sisira H

    2016-09-01

    Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734) were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence) and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1) and Bandagiriya (EL2). Albuminuria (ACR ≥ 30mg/g); serum creatinine based estimation of glomerular filtration rate (eGFR); creatinine normalized urinary kidney injury molecule (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were measured. Fourteen new CKDu cases (18%) from EL1 and nine CKDu cases (9%) from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr). No CKDu cases were identified in non-endemic study locations in Matara (CM) and Nuwara Eliya (CN). Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal injury

  9. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka

    Science.gov (United States)

    Mohammed Abdul, Khaja Shameem; Eakanayake, Eakanayake M. D. V.; Jayasinghe, Sudheera Sammanthi; Jayasumana, Channa; Asanthi, Hewa Bandulage; Perera, Hettiarachigae S. D.; Chaminda, Gamage G. Tushara; Chandana, Ediriweera P. S.; Siribaddana, Sisira H.

    2016-01-01

    Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734) were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence) and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1) and Bandagiriya (EL2). Albuminuria (ACR ≥ 30mg/g); serum creatinine based estimation of glomerular filtration rate (eGFR); creatinine normalized urinary kidney injury molecule (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were measured. Fourteen new CKDu cases (18%) from EL1 and nine CKDu cases (9%) from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr). No CKDu cases were identified in non-endemic study locations in Matara (CM) and Nuwara Eliya (CN). Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal injury

  10. Can You Anchor a Shimmering Nation State via Regional Indigenous Roots? Kim Scott talks to Anne Brewster about That Deadman Dance

    Directory of Open Access Journals (Sweden)

    Anne Brewster

    2011-10-01

    Full Text Available This interview focuses mainly on Kim Scott’s new novel That Deadman Dance which won the regional Commonwealth Writers Prize (Southeast Asian and Pacific region and the Miles Franklin Award. The topics of conversation include Scott’s involvement in the Noongar language project (and the relationship of this project to the novel, the novel itself, the challenges of writing in English, the resistance paradigm and indigenous sovereignty and nationalism.

  11. The View From Pyongyang: Prospects for Survival in the 21st Century

    National Research Council Canada - National Science Library

    Neky, Patrick

    2000-01-01

    .... What course will Kim Jong II choose for himself and his country? The political structure of the DPRK has been deliberately crafted to focus all meaningful power and decision-making on the person of Kim Jong II and retains no ability to reform itself...

  12. Creating Learning: A Korean Drummer's Lifelong Quest to Be the Best

    Science.gov (United States)

    Kang, Dae Joong

    2010-01-01

    In this article, the author interrogates how one famous Korean traditional drummer Mr. Myong-hwan Kim's lifelong learning is affected by the sociocultural and historical context as it contributes to the construction of his life. This article analyzed an oral history book that contains Mr. Kim's interview narratives since he died 20 years ago.…

  13. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus.

    Science.gov (United States)

    Fufaa, Gudeta D; Weil, E Jennifer; Nelson, Robert G; Hanson, Robert L; Bonventre, Joseph V; Sabbisetti, Venkata; Waikar, Sushrut S; Mifflin, Theodore E; Zhang, Xiaoming; Xie, Dawei; Hsu, Chi-Yuan; Feldman, Harold I; Coresh, Josef; Vasan, Ramachandran S; Kimmel, Paul L; Liu, Kathleen D

    2015-01-01

    Kidney injury molecule 1 (KIM-1), liver fatty acid-binding protein (L-FABP), N-acetyl-β-D-glucosaminidase (NAG) and neutrophil gelatinase-associated lipocalin (NGAL) are urinary biomarkers of renal tubular injury. We examined their association with incident end-stage renal disease (ESRD) and all-cause mortality in American Indians with type 2 diabetes. Biomarker concentrations were measured in baseline urine samples in 260 Pima Indians who were followed for a median of 14 years. HRs were reported per SD of creatinine (Cr)-normalised log-transformed KIM-1, NAG and NGAL, and for three categories of L-FABP. During follow-up, 74 participants developed ESRD and 101 died. Median concentrations of KIM-1/Cr, NAG/Cr and NGAL/Cr and the proportion of detectable L-FABP were highest in those with macroalbuminuria (p associated with ESRD (HR 1.59, 95% CI 1.20, 2.11) and mortality (HR 1.39, 95% CI 1.06, 1.82); L-FABP/Cr was inversely associated with ESRD (HR [for highest vs lowest tertile] 0.40, 95% CI 0.19, 0.83). Addition of NGAL/Cr to models that included albuminuria and glomerular filtration rate increased the c-statistic for predicting ESRD from 0.828 to 0.833 (p = 0.001) and for death from 0.710 to 0.722 (p = 0.018). Addition of L-FABP/Cr increased the c-statistic for ESRD from 0.828 to 0.832 (p = 0.042). In Pima Indians with type 2 diabetes, urinary concentrations of NGAL and L-FABP are associated with important health outcomes, but they are unlikely to add to risk prediction with standard markers in a clinically meaningful way given the small increase in the c-statistic.

  14. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu among Agricultural Communities in Sri Lanka.

    Directory of Open Access Journals (Sweden)

    Pallagae Mangala C S De Silva

    2016-09-01

    Full Text Available Chronic Kidney Disease of uncertain etiology (CKDu is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734 were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1 and Bandagiriya (EL2. Albuminuria (ACR ≥ 30mg/g; serum creatinine based estimation of glomerular filtration rate (eGFR; creatinine normalized urinary kidney injury molecule (KIM-1 and neutrophil gelatinase-associated lipocalin (NGAL were measured. Fourteen new CKDu cases (18% from EL1 and nine CKDu cases (9% from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr. No CKDu cases were identified in non-endemic study locations in Matara (CM and Nuwara Eliya (CN. Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal

  15. „Ritualno” i „struktuirano” odbacivanje u arheološkim interpretacijama: primer sistema za vodosnabdevanje na lokalitetu „Kale” u Krševici

    Directory of Open Access Journals (Sweden)

    Ivan Vranić

    2016-11-01

    Full Text Available Pitanja vezana za rituale, kultove, religiju ili magiju predstavljaju važne ali u značajnoj meri zanemarene i teorijski nedovoljno precizno utemeljene teme u savremenim arheološkim interpretacijama. Cilj rada jeste da na konkretnim primerima potencijalno ritualnih aktivnosti vezanih za izgradnju i moguće „ritualno ubijanje” sistema za vodosnabdevanje na lokalitetu „Kale” u Krševici pokaže kako ovo zanemarivanje nije samo posledica aktuelnosti i trendova o odabiru istraživačkih tema, već se radi o ozbiljnijem problemu koji pokazuje određene nedostatke savremenih pristupa vezanih za arheologiju identiteta i koncepte struktuiranog ili simboličkog odbacivanja.

  16. The prevalence of musculoskeletal disorders and occupational risk factors in Kashan SAIPA automobile industry workers by key indicator method (KIM, 1390

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Introduction: work related musculoskeletal disorders are the most wide spread type of occupational diseases among workers. Awkward body postures during work and manual material handling are among the most important risk factors of musculoskeletal disorders in different jobs. Due to importance of recognizing these factors prevalence and risk factor of work related musculoskeletal disorders, this research was aimed to study the among employees of Kashan City’s Saipa automobile industry in 2011. .Material and Method: This study is a descriptive-cross sectional study conducted among workers with manual material handling 37 activities and 84 work duties. To recognize musculoskeletal disorders, body map questionnaire was applied and occupational risk factors were evaluated using Key Index Method (KIM. Data was analyzed using SPSS and Excel software. .Result: Highest prevalence of musculoskeletal disorders was in low and upper back region (%92. Based on the results from KIM, workers in the installing the tire, shuttle-aided fitting of seat, and engine work station had higher risk level with the scores of 66, 52 and 52, respectively. Risk level among three individuals (%3.6 was at 1, 40 (%47.6 at 2, 38 (%45.2 risk level 3, and 3 (%3.6 at 4. .Conclusion: Awkward body posture, improper twisting and flexion of low back were major risk factor among worker doing manual material handling tasks. Regarding the high prevalence of musculoskeletal disorders, appropriate ergonomic interventions such as engineering and organization interactions can reduce this risk factors (posture, heavy load, duration, workplace conditions as much as the risk level reach to an acceptable level.

  17. "The Day All of the Different Parts of Me Can Come Along": Intersectionality and U.S. Third World Feminism in the Poetry of Pat Parker and Willyce Kim.

    Science.gov (United States)

    Van Ausdall, Mimi Iimuro

    2015-01-01

    This article brings to light the poetry of Pat Parker and Willyce Kim, two key figures within the 1970s and '80s women in print movement. While Parker and Kim have been rightly placed within African-American and Asian-American histories, respectively, and working-class and lesbian-feminist literary histories, their work is most fully understood within the context of U.S. Third World Feminism. Through close readings of poetic form and content in addition to engagement with current debates about intersectionality as a methodology, the article links Kim and Parker's works to central contributions of U.S. Third World Feminism such as intersectionality and power across and within difference that continue to influence feminist theory today.

  18. Analysis of the coexisting pathways for NO and N2O formation in Chernozem using the (15)N-tracer SimKIM-Advanced model.

    Science.gov (United States)

    Stange, Claus Florian; Spott, Oliver; Russow, Rolf

    2013-01-01

    The nitrogen (N) cycle consists of a variety of microbial processes. These processes often occur simultaneously in soils, but respond differently to local environmental conditions due to process-specific biochemical restrictions (e.g. oxygen levels). Hence, soil nitrogen cycling (e.g. soil N gas production through nitrification and denitrification) is individually affected through these processes, resulting in the complex and highly dynamic behaviour of total soil N turnover. The development and application of methods that facilitate the quantification of individual contributions of coexisting processes is a fundamental prerequisite for (i) understanding the dynamics of soil N turnover and (ii) implementing these processes in ecosystem models. To explain the unexpected results of the triplet tracer experiment (TTE) of Russow et al. (Role of nitrite and nitric oxide in the processes of nitrification and denitrification in soil: results from (15)N tracer experiments. Soil Biol Biochem. 2009;41:785-795) the existing SimKIM model was extended to the SimKIM-Advanced model through the addition of three separate nitrite subpools associated with ammonia oxidation, oxidation of organic nitrogen (Norg), and denitrification, respectively. For the TTE, individual treatments with (15)N ammonium, (15)N nitrate, and (15)N nitrite were conducted under oxic, hypoxic, and anoxic conditions, respectively, to clarify the role of nitric oxide as a denitrification intermediate during N2O formation. Using a split nitrite pool, this analysis model explains the observed differences in the (15)N enrichments in nitric oxide (NO) and nitrous oxide (N2O) which occurred in dependence on different oxygen concentrations. The change from oxic over hypoxic to anoxic conditions only marginally increased the NO and N2O release rates (1.3-fold). The analysis using the model revealed that, under oxic and hypoxic conditions, Norg-based N2O production was the dominant pathway, contributing to 90 and 50

  19. Urinary Vitamin D Binding Protein and KIM-1 Are Potent New Biomarkers of Major Adverse Renal Events in Patients Undergoing Coronary Angiography.

    Directory of Open Access Journals (Sweden)

    Lyubov Chaykovska

    Full Text Available Vitamin-D-binding protein (VDBP is a low molecular weight protein that is filtered through the glomerulus as a 25-(OH vitamin D 3/VDBP complex. In the normal kidney VDBP is reabsorbed and catabolized by proximal tubule epithelial cells reducing the urinary excretion to trace amounts. Acute tubular injury is expected to result in urinary VDBP loss. The purpose of our study was to explore the potential role of urinary VDBP as a biomarker of an acute renal damage.We included 314 patients with diabetes mellitus or mild renal impairment undergoing coronary angiography and collected blood and urine before and 24 hours after the CM application. Patients were followed for 90 days for the composite endpoint major adverse renal events (MARE: need for dialysis, doubling of serum creatinine after 90 days, unplanned emergency rehospitalization or death.Increased urine VDBP concentration 24 hours after contrast media exposure was predictive for dialysis need (no dialysis: 113.06 ± 299.61 ng/ml, n = 303; need for dialysis: 613.07 ± 700.45 ng/ml, n = 11, Mean ± SD, p<0.001, death (no death during follow-up: 121.41 ± 324.45 ng/ml, n = 306; death during follow-up: 522.01 ± 521.86 ng/ml, n = 8; Mean ± SD, p<0.003 and MARE (no MARE: 112.08 ± 302.00 ng/ml, n = 298; MARE: 506.16 ± 624.61 ng/ml, n = 16, Mean ± SD, p<0.001 during the follow-up of 90 days after contrast media exposure. Correction of urine VDBP concentrations for creatinine excretion confirmed its predictive value and was consistent with increased levels of urinary Kidney Injury Molecule-1 (KIM-1 and baseline plasma creatinine in patients with above mentioned complications. The impact of urinary VDBP and KIM-1 on MARE was independent of known CIN risk factors such as anemia, preexisting renal failure, preexisting heart failure, and diabetes.Urinary VDBP is a promising novel biomarker of major contrast induced nephropathy-associated events 90 days after contrast media exposure.

  20. Kim Davis: A Mother's Dilemma.

    Science.gov (United States)

    Hudecki, Michael S.

    2000-01-01

    Presents a discussion case in which parents must decide whether or not to enroll their sons in an experimental treatment program for muscular dystrophy. Identifies teaching objectives and discusses the key issues of the case--muscle structure and function, muscular dystrophy, scientists and money, scientific method and the FDA, and family health…

  1. Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine.

    Science.gov (United States)

    Zhang, Jun; Goering, Peter L; Espandiari, Parvaneh; Shaw, Martin; Bonventre, Joseph V; Vaidya, Vishal S; Brown, Ronald P; Keenan, Joe; Kilty, Cormac G; Sadrieh, Nakissa; Hanig, Joseph P

    2009-08-01

    The present study compared the immunolocalization of Kim-1, renal papillary antigen (RPA)-1, and RPA-2 with that of inducible nitric oxide synthase (iNOS) and nitrotyrosine in kidneys of gentamicin sulfate (Gen)- and cisplatin (Cis)-treated rats. The specificity of acute kidney injury (AKI) biomarkers, iNOS, and nitrotyrosine was evaluated by dosing rats with valproic acid (VPA). Sprague-Dawley (SD) rats were injected subcutaneously (sc) with 100 mg/kg/day of Gen for six or fourteen days; a single intraperitoneal (ip) dose of 1, 3, or 6 mg/kg of Cis; or 650 mg/kg/day of VPA (ip) for four days. In Gen-treated rats, Kim-1 was expressed in the epithelial cells, mainly in the S1/S2 segments but less so in the S3 segment, and RPA-1 was increased in the epithelial cells of collecting ducts (CD) in the cortex. Spatial expression of iNOS or nitrotyrosine with Kim-1 or RPA-1 was detected. In Cis-treated rats, Kim-1 was expressed only in the S3 segment cells, and RPA-1 and RPA-2 were increased in the epithelial cells of medullary CD or medullary loop of Henle (LH), respectively. Spatial expression of iNOS or nitrotyrosine with RPA-1 or RPA-2 was also identified. These findings suggest that peroxynitrite formation may be involved in the pathogenesis of Gen and Cis nephrotoxicity and that Kim-1, RPA-1, and RPA-2 have the potential to serve as site-specific biomarkers for Gen or Cis AKI.

  2. Standards of Justice for Human Being and Doing in Kim Stanley Robinson’s 2312 and C. S. Friedman’s This Alien Shore

    Directory of Open Access Journals (Sweden)

    Claire P. Curtis

    2017-09-01

    Full Text Available The creation of superior societies and communities in which bodies live better and thrive depends on richly detailed accounts of imagined societies including flexible theories of justice that can be used to evaluate them. Both Kim Stanley Robinson’s '2312' (2012 and C. S. Friedman’s 'This Alien Shore' (1998 attempt to rethink what bodies can do and be, by exploring ways of living together among those with different, and differently compatible, bodies. The novels are set in future spacefaring societies away from the Earth, which nevertheless struggle with the fact of Earth’s existence. Each novel describes radical cognitive and bodily change: chosen alteration in '2312' and environmental transformation in 'This Alien Shore'. In each novel, the body, and what bodies can do and be, is a central issue. But how might we evaluate the societies these novels describe to gauge their contributions to articulating desires for a better way of being? In this article I employ Martha Nussbaum’s ‘capabilities approach’ (encompassing life, bodily health, bodily integrity, senses, emotions, reason, affiliation, play, other species, control over environment to think about justice in the articulation of evaluative standards. In so doing the analysis I develop addresses some key questions raised by these novels, including: Whose body will matter? Will there be bodily norms? How will communities confront different bodily abilities? How can we enhance our own thinking about how to live in and among bodies? How does (and should the idea of the body politic change when our expectations about bodies changes?

  3. Mis toimub Põhja-Koreas? / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2004-01-01

    Infoagentuuri UPI teatel võib Põhja-Korea liider Kim Jong-il olla surnud, avalikest kohtadest on hakatud maha võtma tema portreesid. Põhja-Korea infoagentuur eitab seda. Ekspertide versioonidest Põhja-Koreas toimuva kohta

  4. Implications of Competition for Rare Earth Elements (REE) in Africa

    Science.gov (United States)

    2011-03-15

    their nuclear programs as well. To emphasize North Korea’s national concern over the issue, Kim Jong Il visited the Hamhung Semiconductor Materials...Chain,‖ (September 30, 2010): Summary Section. 37 16 Ibid, 4. 17 ― Kim Jong IL Provides Field Guidance to Factory and Scientific Institution...legitimize its nuclear program by seeking support from countries belonging to the Non-Aligned Movement ( NAM ), most of which come from Africa. Iranian

  5. Abielu, perekonna ja õnnistuse tähendus / Chung Hwan Kwak

    Index Scriptorium Estoniae

    Kwak, Chung Hwan

    2002-01-01

    Ettekanne Rahvusvahelise ja Relgioonidevahelise Föderatsiooni Maailmarahu eest (IIFWP) Tallinnas peetud seminaril "Riigi uuendamine: perekondi tugevdavate, meie noori kasvatavate ja ühiskonda taasehitavate printsiipide ja praktikate uurimine" : lühendatult

  6. Expression of porcine myosin heavy chain 1 gene in Berkshire loins ...

    African Journals Online (AJOL)

    Expression of porcine myosin heavy chain 1 gene in Berkshire loins with a high pH24 value. Jin Hun Kang, Woo Young Bang, Eun Jung Kwon, Yong Hwa Lee, Da Hye Park, Eun Seok Cho, Min Ji Kim, Jong-Soon Choi, Hwa Chun Park, Beom Young Park, Chul Wook Kim ...

  7. Comparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats

    Directory of Open Access Journals (Sweden)

    Lee IC

    2016-06-01

    Full Text Available In-Chul Lee,1 Je-Won Ko,1 Sung-Hyeuk Park,1 Je-Oh Lim,1 In-Sik Shin,1 Changjong Moon,1 Sung-Hwan Kim,2 Jeong-Doo Heo,3 Jong-Choon Kim1 1College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 2Jeonbuk Department of Inhalation Research, Korea Institute of Toxicology, Jeongeup, 3Gyeongnam Department of Environment and Toxicology, Korea Institute of Toxicology, Gyeongnam, Republic of Korea Abstract: Despite widespread use and prospective biomedical applications of copper nanoparticles (Cu NPs, their biosafety issues and kinetics remain unclear. Thus, the aim of this study was to compare the detailed in vivo toxicity of Cu NPs and cupric ions (CuCl2; Cu ions after a single oral dose. We determined the physicochemical characteristics of Cu NPs, including morphology, hydrodynamic size, zeta potential, and dissolution in gastric (pH 1.5, vehicle (pH 6.5, and intestinal (pH 7.8 conditions. We also evaluated the kinetics of Cu following a single equivalent dose (500 mg/kg of Cu NPs and Cu ions. Cu NPs had highest dissolution (84.5% only in gastric conditions when compared with complete dissolution of Cu ions under various physiological milieus. Kinetic analysis revealed that highest Cu levels in blood and tested organs of Cu NP-treated rats were 15%–25% lower than that of Cu ions. Similar to the case of Cu ions, Cu levels in the tested organs (especially liver, kidney, and spleen of Cu NP-treated rats increased significantly when compared with the vehicle control. However, delay in reaching the highest level and biopersistence of Cu were observed in the blood and tested organs of Cu NP-treated rats compared with Cu ions. Extremely high levels of Cu in feces indicated that unabsorbed Cu NPs or absorbed Cu ions were predominantly eliminated through liver/feces. Cu NPs exerted apparent toxicological effects at higher dose levels compared with Cu ions and showed sex-dependent differences in mortality, biochemistry, and

  8. Association between vitamin D receptor polymorphisms and osteoporosis in patients with COPD

    Directory of Open Access Journals (Sweden)

    Kim SW

    2015-09-01

    Full Text Available Sei Won Kim,1 Jong Min Lee,1 Jick Hwan Ha,1 Hyeon Hui Kang,1 Chin Kook Rhee,1 Jin Woo Kim,1 Hwa Sik Moon,1 Ki Hyun Baek,2 Sang Haak Lee1 1Division of Pulmonology, Critical Care and Sleep Medicine, 2Division of Endocrinology and Metabolism, Department of Internal Medicine, St Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Background: Patients with COPD are at an increased risk of osteoporosis. Although many studies have addressed the relationship between the vitamin D receptor (VDR polymorphisms and bone health, this relationship has not been fully investigated in patients with COPD. In this study, we investigated the association of VDR polymorphisms with bone mineral density (BMD and other clinical parameters in patients with COPD. Patients and methods: In total, 200 patients with COPD were included in this study. The VDR polymorphisms rs1544410 (A/G-BsmI, rs7975232 (A/C-ApaI, rs731236 (C/T-TaqI, and rs10735810 (C/T-FokI were determined by Sanger sequencing using blood DNA samples. BMD of the lumbar vertebra and the femoral neck was measured by dual-energy X-ray absorptiometry. Other clinical parameters were also evaluated. Haplotype and multivariate analyses were also performed. Results: Sex, body mass index, steroid use, percentage of forced expiratory volume in 1 second (FEV1, alkaline phosphatase, and 25-hydroxyvitamin D significantly influenced the risk of osteoporosis. Patients with osteoporosis were more likely to carry the rs7975232 C allele compared to normal patients with BMD. Haplotypes GCT and GAT were related to osteoporosis. Patients without the haplotype GAT allele showed a significantly lower T-score at the femoral neck and an increased risk of osteoporosis (odds ratio [OR]= 2.78, 95% confidence interval [CI]= 1.20–6.48, P=0.018 compared with carriers in the dominant model. Conclusion: Genetic variations in VDR are significantly associated with osteoporosis among patients with COPD

  9. North Korean Policy Elites

    Science.gov (United States)

    2004-06-01

    by Kim’s former Japanese chef , Kenji Fujimoto, reveal that Kim could get just about anything he wanted in his personal life, from foreign delicacies...for his table to Japanese jet skis and Sony home electronics.9 Likewise, the account of Yi Nam-oak (Li Nam-ok), who grew up as a companion to Kim’s...title Kin Seinichi no Ryoryinin [Kim Jong-il’s Chef ], Tokyo: Fusosha, 2003. The title of the Korean edition is Kim Jong-il ui yorisa. FBIS translated

  10. A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

    Science.gov (United States)

    2015-07-21

    Hybrid Biosensor Jieun Lee1,2, Jaeman Jang1, Bongsik Choi1, Jinsu Yoon1, Jee-Yeon Kim3, Yang-Kyu Choi3, Dong Myong Kim1, Dae Hwan Kim1 & Sung-Jin Choi1...This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response...of field-effect-transistor (FET)-based biosensors . The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential

  11. Jong lesers se identifisering met karakters: skryfteorie en -praktyk

    Directory of Open Access Journals (Sweden)

    F. Greyling

    2005-07-01

    Full Text Available Young readers’ identification with characters: the theory and practice of creative writing It is generally acknowledged that reader identification with characters contributes to readers’ involvement in the text and the subsequent pleasure derived from reading stories. It seems that establishing a relationship with the implied reader of the text comes naturally for successful authors. There is, however, a lack of coherent theory on reader identification with characters which can be used in the teaching of creative writing. This article combines insights gained from various disciplines in order to develop a coherent theory of the phenomenon of reader identification. Of special interest are the results of reader-response research regarding the relation between individuals’ development phase and identification with characters. Some of the possibilities which the writer can utilise to establish a relationship with the reader and influence the nature of reader identification with characters are the choice of characters and their depiction in the text, the narrative strategy and the use of viewpoint.

  12. Drugs in een plattelandsgemeente. Een vervolgonderzoek bij jonge hashisgebruikers

    NARCIS (Netherlands)

    Timmerman, Harmannus

    1977-01-01

    In deze studie hebben we de resultaten gepresenteerd van een vervolgonderzoek naar de gevolgen van het druggebruik in een plattelandsgemeente (t.w. Gieten). Zoals uit dit onderzoek blijkt, kwamen uit een gebruikersgroep zoals onze house-bezoekers, geen mensen die afhankelijk zijn geworden van

  13. Leipoldt en Diponegoro | De Jong | South African Journal of Cultural ...

    African Journals Online (AJOL)

    He was the leader of a stubborn rising, the Java War in 1825-1830. He is now one of the great heroes of Indonesian nationalism. The work "Visit to the East Indies" states that Leipoldt left the 'Ulysses' in Amsterdam and visited the Rijksmuseum there to view the painting by Nicolaas Pieneman, Dutch painter, of the surrender ...

  14. Jong wonen: de gewoonste zaak van de wereld?

    NARCIS (Netherlands)

    Schnabel, P.; Kullberg, J.

    2006-01-01

    Als het om wonen gaat, denken we vaak in stereotype beelden. Ook bij het plannen en ontwikkelen van wijken lijken we weinig rekening to houden met de belevingswereld van de individuele mens. We gaan uit van concrete parameters als programma's, doelgroepen, budgetten en dichtheden. We spreken over

  15. Die jong kind se belewenis van intensiewe sportdeelname ...

    African Journals Online (AJOL)

    sport far more negatively than parents and coaches would suppose. Girls also experience intensive participation in sport more negatively than boys, while individual sport types are inclined to be more stressful for young children than team sports. Competition anxiety, followed by spectator behaviour and pressure to perform

  16. Vriendschappen tussen jong en oud in 25 Europese landen

    NARCIS (Netherlands)

    P.A. Dykstra (Pearl); M. Fleischmann (Maria)

    2016-01-01

    markdownabstract_Cross-age friendships in 25 European countries_ This paper focuses on individual and country-level circumstances shaping friendships between young and old to gain insight into conditions for intergenerational solidarity. Using European Social Survey data, findings show that

  17. De bijdrage van leefstijl aan gewichtsstijging bij jong volwassenen

    NARCIS (Netherlands)

    Wendel-Vos GCW; Nooyens ACJ; Schuit AJ; PZO

    2004-01-01

    In this report, the contribution of lifestyle to weight gain in young adults is addressed. Aspects of lifestyle factors associated with weight gain differ between men and women. For example, among men consumption of savoury snacks seemed to be associated with weight gain, whereas among women

  18. Nachtvorst en microklimaat : in het bijzonder in jonge bosaanplant

    NARCIS (Netherlands)

    Schneider, T.

    1967-01-01

    In forestry frost may cause considerable damage. A purpose of this publication was to consider whether any of the many methods of preventing frost were suitable for forestry. Much of the research was devoted to a description of the microclimate and the relation between the physical phenomena

  19. Baseline characteristics and response to 2 years of growth hormone (GH) replacement of hypopituitary patients with GH deficiency due to adult-onset craniopharyngioma in comparison with patients with nonfunctioning pituitary adenoma: data from KIMS (Pfizer International Metabolic Database).

    Science.gov (United States)

    Verhelst, Johan; Kendall-Taylor, Pat; Erfurth, Eva Marie; Price, David Anthony; Geffner, Mitchell; Koltowska-Häggström, Maria; Jönsson, Peter J; Wilton, Patrick; Abs, Roger

    2005-08-01

    In epidemiological studies, hypopituitary adults show increased mortality compared with population controls. Patients with hypopituitarism caused by a craniopharyngioma (CP) and/or its treatment have a higher mortality than patients with other etiologies, such as a nonfunctioning pituitary adenoma (NFPA). To analyze this difference, we used the KIMS database (Pfizer International Metabolic Database) comparing CP and NFPA patients in terms of baseline characteristics and responses to GH replacement. Baseline characteristics were studied in 351 CP patients (189 men and 162 women; mean age, 42.5 yr) and compared with 370 NFPA patients, matched for age and sex (185 men and 185 women; mean age, 42.5 yr). The effects of 2 yr of GH replacement were analyzed in a subgroup of 183 CP and 209 NFPA patients. At baseline, both CP and NFPA patients had characteristic features of GH deficiency, with low serum IGF-I, increased body fat, dyslipidemia, and reduced quality of life. Male CP patients were significantly more obese (30.0 vs. 28.2 kg/m2; P = 0.0003) compared with NFPA patients, had a higher waist/hip ratio (P = 0.004), higher triglycerides (P = 0.003), and lower high-density lipoprotein cholesterol (P = 0.03). Similar, but much smaller, differences were seen in female CP compared with NFPA patients, only reaching significance for waist/hip ratio (P = 0.05) and triglycerides (P = 0.0004). CP patients had more often undergone surgery by the transcranial route (68.8% vs. 30.9%; P NFPA patients (58.7% vs. 19.8%; P NFPA patients. After 2 yr of GH replacement therapy, similar significant improvements were evident in both groups in fat-free mass, total and low-density lipoprotein cholesterol, and Quality-of-Life-Assessment in GH Deficient Adults score compared with baseline. In contrast to NFPA patients, CP patients had no significant decrease in body fat with GH therapy. In the KIMS database, patients with CP have more often undergone surgery by the transcranial route than

  20. Retarderi na teškim vozilima

    Directory of Open Access Journals (Sweden)

    Joško Rapanić

    2012-10-01

    Full Text Available The objective of all the braking systems fitted in vehicles isto reduce the speed, as well as to keep them at a standstill. Inorder to increase the active road traffic safety, the experts inthe leading vehicle manufacturer companies are trying from day to day to find a more efficient solution of the highest possiblequality. Braking problems, i.e. problems of stopping the vehiclesare closely related to time, forces, momentum, mass andother physical quantities. This is best seen in the braking ofheavy duty vehicles, trucks, buses, where the braking efficacyis questionable due to high inertia forces caused by heavyweight and more recently relatively high speeds. Such vehiclesare fitted with system of brakes that operate on compressed airor combination of pneumatics and hydraulics, since the driverhas not got enough power to achieve appropriate braking effect.However, the biggest problems occur by trucks runningdownhill, when the braking system is operated continuously fora longer period of time. This causes heating and overheating ofthe system elements ("fading", thus reducing the braking effect.In extreme cases, particularly if the system is poorly maintained,it can eventually fail completely.Because of the mentioned reasons for difficulties in brakingof trucks, such vehicles have been recently fitted with anauxiliary slow-down system. This system is completely independentfromthe main one on the wheels and is used exclusivelyfor slowing down or for maintaining of speed.

  1. Ajateenistusest, ausalt! / Kim Järvepõld

    Index Scriptorium Estoniae

    Järvepõld, Kim

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 9. apr. 2007, lk. 7. Autor leiab, et põhiseaduslik nõue, mille järgi on kõik Eesti kodanikud kohustatud osa võtma riigikaitsest, pole vastavuses tegeliku olukorraga, ning arvab, et kohustuslik ajateenistus tuleb kaotada või viia kooskõlla põhiseadusega

  2. kim Tasarım ve Ekşi Sözlük: İnternet’in Dönüşümünü Anlamak

    Directory of Open Access Journals (Sweden)

    Babacan Taşdemir

    2014-02-01

    Full Text Available Son yıllarda bir yanda devletler, diğer yanda sermaye kuruluşları, siyasi, idari ve ticari amaçları ile İnternet ortamını gittikçe daha fazla kolonileştirmektedirler. Bu da siyasi ve ticari baskılardan azade bir özgürlük alanı olarak görülen İnternet’e ilişkin toplumsal beklentilere zıt bir durum ortaya çıkarmaktadır. Çalışmamız, İnternet’teki bu dönüşümü üretim gücü ve üretim ilişkileri kavramları üzerinden eleştirel bir gözle değerlendirmeyi önermektedir. Dönüşüm, ‘Teknolojik Değişimin Döngüsel Modeli’ndeki ‘mayalanma dönemi’ ve ‘hâkim tasarım’ kavramlarının sunduğu potansiyelden faydalanılarak açıklanmaya çalışılmaktadır.  Burada ‘mayalanma dönemi’ ile İnternette ifade özgürlüğü açısından daha uygun olan ilk dönemlere, ‘hâkim tasarım’ ile ise yerleşik üretim ve iktidar ilişkilerinin daha fazla nüfuz ettiği yakın döneme gönderme yapılmaktadır. Ekşi Sözlük örneği ile de savlarını destekleyen çalışmamız, üç kategori üzerinden örnek olaylarla Sözlük’ün dönüşümünü değerlendirmektedir: İş çevreleriyle ticari ilişkilere bağlı dönüşüm, İnternet’in düzenlenmesine dair hukuki çerçeve ve kamu otoriteleri ile ilişkilere bağlı olarak geçirilen dönüşüm, Sözlük kullanıcıları ve sahipleri arasındaki örgütsel ilişkinin değişimi dolayımında geçirilen dönüşüm. Sonuç olarak, İnternet’in ‘mayalanma döneminde’, yani görece serbest bir ortamda, Ekşi Sözlük popülaritesini ve saygınlığını, yaratıcı ve muhalif duruş ile karakterize olan bir ifade alanı olarak kazansa da, zaman içinde tamamen kâr merkezli bir işletmeye dönüşmektedir. Böylece bir yandan pazarlama stratejilerinin ana mecralarından biri diğer yandan da politik baskıya tabii sıradan bir forum ve paylaşım sitesi haline gelmektedir. Sözlük’ün gelişimine ilişkin örnek olaylar ele

  3. Vorinostat-eluting poly(DL-lactide-co-glycolide) nanofiber-coated stent for inhibition of cholangiocarcinoma cells

    OpenAIRE

    Kwak TW; Lee HL; Song YH; Kim C; Kim JS; Seo SJ; Jeong YI; Kang DH

    2017-01-01

    Tae Won Kwak,1,* Hye Lim Lee,2,* Yeon Hui Song,2 Chan Kim,3 Jungsoo Kim,2 Sol-Ji Seo,2 Young-Il Jeong,2 Dae Hwan Kang2,4 1Medical Convergence Textile Center, Gyeongbuk, Republic of Korea; 2Biomedical Research Institute, Pusan National University Hospital, Pusan, Republic of Korea; 3Amogreentech Co. Ltd. Gyeonggi-do, Republic of Korea; 4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongnam, Republic of Korea *These auth...

  4. Kim, czym, kiedy, gdzie i dlaczego są polscy Żydzi? Wyobrażanie, konstruowanie i zawłaszczanie Żydów polskich

    Directory of Open Access Journals (Sweden)

    Scott Ury

    2017-12-01

    Full Text Available Who, what, when, where, and why is Polish Jewry? Envisioning, constructing, and possessing Polish Jewry This article examines the different ways that various communities of scholars imagine, research and teach about “Polish Jewry.” Focusing on scholarship written in Israel, Poland and the United States over the past generation or two, the article argues that each particular community of scholars constructs a particular version of Polish Jewry and that each of these versions is deeply influenced by contemporary social, political and communal needs and demands. As a result, scholars very often end up constructing radically different versions of Polish Jewish history and society. These scholarly differences reflect many of the challenges and difficulties related to researching and writing about the history and culture of Polish Jews since 1989.   Kim, czym, kiedy, gdzie i dlaczego są polscy Żydzi? Wyobrażanie, konstruowanie i zawłaszczanie Żydów polskich Artykuł stanowi omówienie odmiennych sposobów, jakimi różne społeczności badaczy wyobrażają grupę polskich Żydów, badają ją i nauczają o niej. Na podstawie analizy działalności naukowej badaczy z Izraela, Polski i Stanów Zjednoczonych ostatnich dwóch pokoleń autor pokazuje, że każda społeczność badaczy konstruuje własny, specyficzny obraz grupy zwanej „polskimi Żydami” i że obrazy te pozostają pod przemożnym wpływem współczesnych potrzeb i wymogów o naturze społecznej, politycznej i wspólnotowej. Na skutek tych różnic uczeni tworzą często radykalnie odmienne obrazy historii i społeczeństwa polskich Żydów. Różnice stanowią odzwierciedlenie przeszkód i utrudnień, jakie po 1989 roku wiążą się z badaniem i opisywaniem historii i kultury polskich Żydów.

  5. Keeping Kim; How the Kim Conundrum Best Serves American Interests in the Asia Pacific

    Science.gov (United States)

    2018-04-18

    Bombs South Korea’s Yeonpyeong Island," The Telegraph, November 23. 2010. http://www.telegraph.co.uk/news/worldnews/asia...southkorea/8153000/North-Korea- bombs -South-Koreas- Yeonpyeong-Island.html (accessed 01/05/2017, 2017). 25 A key initiative during the Sunshine Policy was...tr ad in g pa rt ne r Sa m e et hn ic ity ; di ff er en t sy st em o f go ve rn an ce So ve re ig nt y iss ue s a lw ay s co ns id er ed

  6. El individuo en el cambio: la transformación de las relaciones bilaterales entre la República de Corea y la República Popular Democrática de Corea, bajo la figura del presidente surcoreano Kim Dae-Jung

    OpenAIRE

    Perilla Moreno, Jairo Andrés

    2017-01-01

    Este artículo busca interpretar el proceso mediante el cual las ideas y presupuestos políticos y sociales del expresidente surcoreano Kim Dae-Jung, permitieron una transformación significativa de las relaciones bilaterales entre Corea del Sur y Corea del Norte, durante su periodo presidencial entre los años 1998 y 2003. Inicialmente, dichas relaciones estuvieron caracterizadas por una incesante tensión militar como resultado de la Guerra de Corea, escenario dentro del cual apareció la figura ...

  7. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Ravi P Agarwal1 Jong Kyu Kim2 Donal O' Regan3. Department of Mathematical Sciences, Florida Institute of Technology, Melbourne, Florida 32901-6975, USA; Department of Mathematics, Kyungnam University, Masan, Kyungnam 631-701, Korea; Department of Mathematics, National University of Ireland, Galway, Ireland ...

  8. Семья Ким сохранит власть в КНДР / Юрген Тамме

    Index Scriptorium Estoniae

    Тамме, Юрген

    2011-01-01

    Põhja-Korea võimukorralduses toimuvat ümbritseb salapära. Kim jong-uni nooruse ja kogenematuse tõttu arvatakse, et lähiaastail juhib Põhja- Koread nõunikkond, kes aitab Kimil end eliidi seas kehtestada. Võimuvõitlus Põhja-Koreas

  9. Kimid hoiavad diktaatoritooli / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2011-01-01

    Põhja-Korea võimukorralduses toimuvat ümbritseb salapära. Kim jong-uni nooruse ja kogenematuse tõttu arvatakse, et lähiaastail juhib Põhja- Koread nõunikkond, kes aitab Kimil end eliidi seas kehtestada. Võimuvõitlus Põhja-Koreas

  10. Usmirenije Severnoi Korei / Joseph S. Nye ; tõlk. Nikolai Zhdanovitsh

    Index Scriptorium Estoniae

    Nye, Joseph S.

    2006-01-01

    USA president George Bush lootis, et tal õnnestub Põhja-Korea tuumaprobleemi lahendada režiimi vahetamisega. Arvestati, et isolatsioon ja sanktsioonid viivad Kim Jong Il'i diktatuuri kukutamiseni. Kuna režiim osutus vastupidavaks, nõustuti kuuepoolsete läbirääkimistega Hiina, Venemaa, Jaapani ja mõlema Koreaga

  11. В Южной Корее вновь пишут о болезни Ким Чен Ира / Эвелин Калдоя

    Index Scriptorium Estoniae

    Калдоя, Эвелин, 1980-

    2009-01-01

    Viidates Lõuna-Korea ja Hiina luureandmetele, väidab Lõuna-Korea meedia, et Põhja-Korea liidril Kim Jong-ilil on kõhunäärmevähk ja talle pole antud elada rohkem kui 5 aastat. Põhja-Korea valitsejadünastia

  12. Kahe Korea liidrid võtsid vahelduseks jälle rahukursi / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2007-01-01

    Kohtusid Põhja- ja Lõuna-Korea juhid Kim Jong-il ja Roh Moo-hyun. Vastuvõetud deklaratsioonis ei puudutata tuumarelvaküsimust ega käsitleta sõjavange, kes jäid Põhja-Korea surmalaagritesse. Lisa: Lubadusi antakse ohtralt, täitma neid ei kiirustata

  13. kim Seyyid Mehmed And His Book Called Nazire-i Hilye-i Hâkanî / HÂKİM SEYYİD MEHMED EFENDİ’NİN “NAZİRE-İ HİLYE-İ HÂKANΔ ADLI ESERİ

    Directory of Open Access Journals (Sweden)

    Yakup POYRAZ (M.A.H.

    2007-08-01

    Full Text Available As a result of the deep divine love people had for our Prophet, various literarytypes such as mevlit and na’t appeared. Of these types, hilye is one of the morepopular ones. Hilyes describe our Prophet physically and morally and theyusually convey the divine love poets have for him. The best-known hilye inTurkish literature, Hilye-i Hâkanî, was written by Hâkanî Mehmet Bey in 16thcentury. One of the nazires written in this hilye belongs to Hâkim SeyyidMehmed who was an 8th century poet. This nazire is usually regarded as one ofthe best in Hilye-i Hâkanî. In this article investigated Hilye-i Hâkanî and madeuseful form to literature.

  14. Transducing a Sermon, Inducing Conversion

    OpenAIRE

    Harkness, Nicholas H.

    2017-01-01

    This paper is an analysis of the final sermon of Billy Graham’s 1973 Crusade in Seoul, South Korea, when he preached to a crowd estimated to exceed one million people. Next to Graham at the pulpit was Billy Jang Hwan Kim, a preacher who, in his capacity as interpreter, translated Graham’s sermon verbally and peri-verbally—utterance by utterance, tone by tone, gesture by gesture—for the Koreanspeaking audience. I examine the dynamic pragmatics (for example, chronotopic formulations, deictic ca...

  15. Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

    OpenAIRE

    Yoon, Seonghae; Lee, Howard; Kim, Tae-Eun; Lee, SeungHwan; Chee, Dong-Hyun; Cho, Joo-Youn; Yu, Kyung-Sang; Jang, In-Jin

    2014-01-01

    Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER...

  16. RAZLIKE U MOTORIČKIM SPOSOBNOSTIMA BOKSERA I NESPORTISTA

    Directory of Open Access Journals (Sweden)

    Benin Murić

    2011-03-01

    Full Text Available This research was conducted with the aim to define differences in motor abilities and morphological characteristics between judists and non/athletes of the same age. Sample encompassed 120 subjects having 60 students non/athletes and 60 students actively engaged in sports. For the evaluation of motor abilities there were conducted 12 measuring instruments. Testing of the posted hypotheses was performed on the basis of statistical data. The obtained results of this research in motor area have shown that there is statistically significant difference between selected boxsers and students not going in for box. This difference is defined by significantly better values and results in motor tests performed by the selected boxers.

  17. Belarus - a unique case in the European context? / Kim Lausten

    Index Scriptorium Estoniae

    Lausten, Kim

    2003-01-01

    Valgevene presidendi Aleksander Lukashenko autoritaarsest režiimist, sellega seonduvatest võimalikest ohtudest Valgevene naaberriikide julgeolekule. Autor analüüsib Lukashenko režiimi institutsioonilisi ning sotsiaalpoliitilisi tagamaid

  18. [Recent books on international law] / Yoonie Kim, Paul R Williams

    Index Scriptorium Estoniae

    Kim, Yoonie

    2005-01-01

    Arvustus: Lauri Mälksoo. Illegal Annexation and State Continuity : The Case of the Incorporation of the Baltic States by the USSR. Study of the Tension between Normativity and Power in International Law. Leiden ; Boston, 2003

  19. Overgewicht bij jonge kinderen en volwassenen: kwantificeren van de kloof tussen energie-inneming en energieverbruik

    NARCIS (Netherlands)

    Berg SW van den; Scholtens S; Wijga AH; Verschuren WMM; Boer JMA; CVG; PZO

    2006-01-01

    For the first time in the Netherlands the gap between energy intake and energy expenditure has been quantified for children and adults. Small daily changes in energy balance may, in the long term, make the difference between becoming overweight or not. Ten per cent of two-year olds either develop

  20. Amerikanen in toga : de Romeinse Republiek als rolmodel voor de jonge Verenigde Staten van Amerika

    NARCIS (Netherlands)

    de Vries, Tietje

    2015-01-01

    Inspired by their education in the classics and their belief that the past was to serve as a model for the presence, the American Founding Fathers took the political system of the early Roman Republic as the basis for the new polity of the independent United States of America. When necessary, they

  1. Tetanus bij een jong ongevaccineerd meisje na een val op straat

    NARCIS (Netherlands)

    Dolman, K. M.; Plötz, F. B.; Wolfs, T. F. W.; Beunders, J. H. J.; van Vught, A. J.

    2002-01-01

    A 4-year-old girl developed tetanus after she had fallen on the street a week before. She had never been vaccinated and despite pressure from the family practitioner, the parents refused to allow her to be given human anti-tetanus immunoglobulin as a matter of principle after the wound had been

  2. Space allowance of young goats during transportation to slaughter = Beladingsdichtheid tijdens het wegtransport van jonge geiten

    NARCIS (Netherlands)

    Hindle, V.A.; Reimert, H.G.M.; Werf, van der J.T.N.; Lambooij, E.

    2011-01-01

    Research was performed during long distance road transportations of young goats (6-8 weeks). Effects of three space allowances on physiological responses (blood parameters, heart rate and body temperature) were measured.

  3. De Nouvelles littéraires: een spraakmakend debuut van een jonge uitgever, 1715-1720

    Directory of Open Access Journals (Sweden)

    Edwin van Meerkerk

    2000-12-01

    Full Text Available Het onderzoek naar zeventiende- en achttiende-eeuwse geleerdentijdschriften heeft al vele interessante studies opgeleverd. Daarbij is echter, zo blijkt uit dit artikel, nooit voldoende onderzocht wat de werkelijke verspreiding van deze periodieken was. De canon die in de literatuur wordt geschetst, komt niet overeen met de werkelijkheid. Een tot nog toe onopgemerkt debuut van een Haagse uitgever stak alle grote tijdschriften naar de kroon.

  4. Learning From Mah Jong - Towards a Multi-Agent System That Can Recognize Graphic Units

    NARCIS (Netherlands)

    Achten, H.H.; Jessurun, A.J.; Chiu, Mao-Lin; Kvan, J.-Y.; Morozumi, M.; Jeng, T.-S.

    2003-01-01

    Sketching is a major means of exploiting the first conceptual developments in architectural design. If we want to support the architect in the ideas-developing phase of design, then we need to understand the conventions of depiction and encoding in drawings. The theory of graphic units provides an

  5. Antenne 2010: trends in alcohol, tabak en drugs bij jonge Amsterdammers

    NARCIS (Netherlands)

    Benschop, A.; Nabben, T.; Korf, D.J.

    2011-01-01

    Since 1993, Amsterdam Antenna has been documenting and analysing trends in nightlife and substance use among Amsterdam young adults and adolescents. Our panel study traces the latest developments every year by holding individual, semi-annual interviews with a panel of avid nightlifers and

  6. De groei van jonge Hevea-oculaties = The growth of young Hevea buddings

    NARCIS (Netherlands)

    Ostendorf, F.W.

    1933-01-01

    Results were presented of studies on the initial growth of Hevea buddings, at the Proefstation West-Java, Buitenzorg (now Bogor). The time elapsing between cutting off the stock above the union and sprouting of the implanted bud was a clonal character; so also was the angle between the young sprout

  7. Asthma Symptoms in Early Childhood: A public health perspective [Astmasymptomen bij jonge kinderen: een volksgezondheids perspectief

    NARCIS (Netherlands)

    Hafkam-de Groen, E.

    2014-01-01

    This thesis focuses on asthma symptoms in early childhood. From a public health perspective, we aim to improve health and health-related quality of life through the prevention of asthma symptoms and by signaling, counselling or management of children who are at a high risk of developing asthma. The

  8. Jonge beginnende automobilisten, hun ongevalsrisico en maatregelen om dit terug te dringen : een literatuurstudie.

    NARCIS (Netherlands)

    Vlakveld, W.P.

    2005-01-01

    Young, novice motorists, their crash rates, and measures to reduce them; A literature study The crash rate of young novice motorists is relatively high worldwide. This study searched the literature to see if research had shown what the causes were of this high crash rate. There were two large

  9. Optical imaging to trace near infrared fluorescent zinc oxide nanoparticles following oral exposure

    Directory of Open Access Journals (Sweden)

    Lee CM

    2012-06-01

    Full Text Available Chang-Moon Lee,1–4,* Hwan-Jeong Jeong,1–4,* Kuk-No Yun,1–3 Dong Wook Kim,1–4 Myung-Hee Sohn,1–4 Jong Kwon Lee,5 Jayoung Jeong,5 Seok Tae Lim1–4 *These authors contributed equally to this work.1Department of Nuclear Medicine; 2Cyclotron Research Center; 3Research Institute of Clinical Medicine; 4Institute for Medical Sciences, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 5Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Osong-Eup, Chungchungbuk-Do, Republic of KoreaBackground: Understanding how nanomaterials are distributed in the body after exposure is important for assessing whether they are safe. In this study, we investigated the behavior and accumulation of nanoscaled and submicron-scaled zinc oxide (ZnO particles in the body using optical imaging following oral exposure.Methods: To trace these nanoparticles in the body, ZnO nanoparticles were conjugated with a monoreactive hydroxysuccinimide ester of Cy5.5 (Cy5.5-NHS, and the conjugation-stabilizing effect of Cy5.5 on the nanoparticles was evaluated in simulated gastric fluid (pH 1.2 for 7 hours. To compare the distribution of Cy5.5-NHS and Cy5.5-conjugated ZnO nanoparticles, Cy5.5-NHS 0.5 mg/kg and Cy5.5-conjugated ZnO nanoparticles 250 mg/kg were administered orally to healthy rats. We collected blood from the rats at predesignated time points for 7 hours after administration, and optical imaging studies were performed at 1, 2, 3, 5, and 7 hours after dosing. To investigate the extent of nanoparticle accumulation in the organs and tissues, the mice were sacrificed at 23 hours after administration, and the organs were removed and imaged.Results: Cy5.5-conjugated ZnO nanoparticles were stable in simulated gastric fluid for 7 hours. The signal intensity of Cy5.5-NHS in blood was highest 3 hours after oral administration, and Cy5.5-conjugated ZnO nanoparticles showed the highest signal

  10. Social-Economic Foundation for Smooth Changes in Korea

    Institute of Scientific and Technical Information of China (English)

    Wang Zaibang

    2012-01-01

    Chairman Kim Jong-il's death has sparked worldwide interest in the 'future direction of the D.P.R.K. political, economic, social and diplomatic policies. After all, as the youngest national leader in the world, Kim Jong-un has little experience, especially as he has been involved in national governance for such a very short time. Whether he earl unite all the high-level leaders of the ruling party, government and military and achieve a smooth transition in national political, economic and social life will affect the well-being of all Korean people, and the security and stability in the whole of Northeast Asia. However, a dispassionate analysis of North Korea's recent economic and social development may show that North Korea's future prospects may not be as gloomy as some people predict.

  11. North Korea’s Nuclear Weapons Development and Diplomacy

    Science.gov (United States)

    2007-01-03

    December 23, 2006. P. A12. Many of Kim Jong-il’s luxury goods purchases have been in Europe. They include Mercedes Benz and BMW automobiles, expensive...small scale atomic bomb. Most believed that North Korea had not reached the technology level to test the prototype of a small nuclear warhead.1 The...and possibly other weapons technology to Iran. There are known divisions within the Chinese government and Communist Party over the issue of support

  12. The North Korean Economy: Overview and Policy Analysis

    Science.gov (United States)

    2007-04-18

    Special Report (1). The Economist, May 3, 2003 (U.S. Edition). 13 See, for example: Natural Wonders Prove Kim Jong-Il’s Divinity: North Korean Media ...clams and matsutake mushrooms are particularly prized in the Japanese market. Japan sends items such as vehicles, electrical machinery, boilers/reactors...client of BDA was widely reported to be conducting “numerous illegal activities, including distributing counterfeit currency and smuggling counterfeit

  13. The Lynchpin Grapples with Frustration and Distrust

    Science.gov (United States)

    2012-06-01

    speaker was alarmed by the Democratic Party’s warning that it will abrogate the KORUS FTA , a bold (some say reckless) strategy for a party that negotiated...the DPRK and China, perhaps even at the expense of the alliance. The KORUS FTA might also be abrogated and fights over issues such as bilateral...assure respect, fulfill a deterrent role, guarantee regime survival, and are useful (to a point) as negotiating cards . With Kim Jong Il’s death, the

  14. North Korea and Support to Terrorism: An Evolving History

    Directory of Open Access Journals (Sweden)

    Bruce E. Bechtol, Jr.

    2010-01-01

    Full Text Available The DPRK's (Democratic People's Republic of Korea or North Korea support for terrorism began as an ideologically-based policy financed by the Soviet Union that eventually led to a policy designed to put money into the coffers of the elite in Pyongyang—in short, a "proliferation for hire" policy. This article articulates a brief history of the North Korean regime, the rise to power of Kim Il-sung and his son, Kim Jong-il, and North Korea's persistent support to terrorist groups around the globe.

  15. De invloed van geïdealiseerde mediabeelden op het zelfbeeld van jonge meisjes: Het positieve effect van mediabewustzijn.

    NARCIS (Netherlands)

    Deen, van der F.S.; Schwinghammer, S.A.; Verkooijen, K.T.

    2011-01-01

    This study examines the influence of idealised (extremely attractive) models appearing in beauty advertisements on the self-image of 10-13 year-old girls and investigates the possible protective role of media awareness. Model attractiveness (idealised vs. normally attractive) and media awareness

  16. Toetsen en trainen van gevaarherkenning : onderzoek naar de toetsbaarheid en trainbaarheid van gevaarherkenning bij jonge beginnende automobilisten in 2007.

    NARCIS (Netherlands)

    Vlakveld, W.P.

    2008-01-01

    Hazard perception is considered to be an essential part of the driving task. In young novice drivers, however, hazard perception still is poorly developed. In its research programme for the period 2007-2010, SWOV therefore wishes to investigate the possibilities to measure and train hazard

  17. Ziet men een tegenstelling tussen jong en oud? Een studie naar de invloed van sociale identificatie, competitie en contact

    NARCIS (Netherlands)

    Pauw, Rodinde; Maas, Ineke

    2015-01-01

    In this study we ask to what extent the Dutch population perceives a conflict between the young and old and how we can explain this. We use Social Identification Theory, Realistic Conflict Theory, and Contact Theory to derive hypotheses. These are tested with newly collected data on a representative

  18. De ontwikkeling van de rijvaardigheid van jonge bromfietsers : een vervolgmeting in 2001, een jaar na een eerder experiment in Leeuwarden

    NARCIS (Netherlands)

    Goldenbeld, C. Houwing, S. & Craen, S. de

    2002-01-01

    In October-November 2000, a field experiment was done in the traffic environment of the city of Leeuwarden, to study the effects of a 16-hour moped driver training on the driving skills of young, inexperienced Dutch moped riders (See ITRD E203869). This report presents the results of a follow-up

  19. A multi-agent Mah Jong playing system : towards real-time recognition of graphic units in graphic representations

    NARCIS (Netherlands)

    Achten, H.H.; Jessurun, A.J.

    2003-01-01

    In architectural design, sketching is an important means to explore the first conceptual developments in the design process. It is necessary to understand the conventions of depiction and encoding in sketches and drawings if we want to support the architect in the sketching activity. The theory of

  20. Over de ontzilting van den bodem in de Wieringermeer : een studie over de zout- en waterbeweging in jonge poldergronden

    NARCIS (Netherlands)

    Zuur, A.J.

    1938-01-01

    The initial concentration of salt in the soil moisture of the Wieringermeer (reclaimed from the sea in 1930) was about 2 %. The moisture content of the soil and hence the salt content in dry matter increased with increasing clay content.
    Percolating rainwater attained the concentration of the

  1. Gunstige invloed van een standaardeliminatiedieet op het gedrag van jonge kinderen met aandachtstekorthyperactiviteitsstoornis (ADHD), een verkennend onderzoek.

    NARCIS (Netherlands)

    Pelsser, L.M.J.

    2002-01-01

    OBJECTIVE: To determine whether a standard elimination diet can decrease the ADHD-symptoms in a heterogeneous group of young children with ADHD. DESIGN: Open, descriptive. METHOD: 40 children, 36 boys and 4 girls, aged 3-7 (average 4.8 years), who met the DSM-IV-criteria for ADHD, followed their

  2. Manuscripts on foundation of Korea nuclear power

    International Nuclear Information System (INIS)

    Park, Ik Su

    1999-12-01

    It is comprised of the manuscripts and recollections on foundation of Korea nuclear power, which includes conversation with Yoon, Se Won, conversation with Choe, Paeng Seop, conversation with Lee, Dong Jip, conversation with Lee, Sang Su, conversation with Kim, Jong Ju, conversation with Lee, Jong Hun, conversation with Youn, Yong Ryeok, conversation with Han, Pil Sun, recollection of my nuclear power by Lee, Chang Gun, recollection of safety regulation in early nuclear power by An, Yeong Ju, recollection of nuclear business in early nuclear power by Lee, Min Ha, recollection of non destructive examination by Je, Hauk, extra story related nuclear power in early period by Heo, Nam and nuclear power and I by Park,Ik Su.

  3. North Korea -- Still an Intelligence Problem

    Directory of Open Access Journals (Sweden)

    Stephan Blancke

    2014-06-01

    Full Text Available A few years after Kim Jong Un came into office, North Korea is still attracting controversy in the headlines, and political sanctions are still in operation. Despite the harsh measures in place to isolate Pyongyang from sources of money and luxury, the rulers are able to get what they want using front companies or the help of other states. The reasons for this are deeply rooted in the North Korean political structure. A network of high ranking officials, their children, and political minions are grappling for power and wealth. Beside the powerful Kim clan there exist other families in North Korea whose loyalty must be secured with bribes. If the loyalty of the influential families is eroded, the power base of Kim Jong Un is likely to soon diminish. As a result, the North Korean government is searching for sources of money. Illicit drugs may be one solution the ruling regime find attractive to this problem, but there appears to be a twist: struggling ordinary citizens are showing signs that they too are taking part in this illegal enterprise. This is manifested by their willingness to become involved in crime in the same way as the corrupt regime.

  4. Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers

    OpenAIRE

    Oh, Minkyung; Park, Sung-Eun; Ghim, Jong-Lyul; Choi, Young-Kyung; Shim, Eon-Jeong; Shin, Jae-Gook; Kim, Eun-Young

    2017-01-01

    Minkyung Oh,1,2,* Sung-Eun Park,3,* Jong-Lyul Ghim,1–3 Young-Kyung Choi,1 Eon-Jeong Shim,1–3 Jae-Gook Shin,1–3 Eun-Young Kim1–3 1Department of Pharmacology, 2PharmacoGenomics Research Center, Inje University College of Medicine, Busan, 3Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, Republic of Korea *These authors contributed equally to this work Objective: This study compared the pharmacokinetic (PK) and safety pro...

  5. Targeting Biological Sensing with Commercial SERS Substrates

    Science.gov (United States)

    2012-09-01

    substrate substrate. Sl x 4 mm waf urement to re ossible contam substrates, fiv resented as an e being used f tigated, and nam eived in an ac cations...targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA," Journal of Drug Targeting, 900-914 (2011). [35] Jong , H.J., Na...J.H., Jin, B.S., Lee, W.K., Lee, W.H., Jung, H.J., Kim , S.C., Lim, S.H., Yu, Y.G., "Identification of Dinitrotoluene Selective Peptides by Phage

  6. Journal Of The Korean Hydrogen Energy Society 2

    International Nuclear Information System (INIS)

    2001-11-01

    This book deals with studies such as new ball-milled metal hydride electrode for rechargeable batteries by Noh, Haki; Park, Chung Nyeon, hydrogen absorption by laves phase related BCC solid solution alloys by Etsuo Akiba. The hydrogen absorption kinetics in very thin pd film by Cho, Young Sin; Lee, Jong Suk; Kim, Chang Won. The effect of the ceramic precipitates on the hydrogen solubility in pd alloys by Koh, Je Mann; Lee, Kil Hong; Bada, Seung Nam; Noh, Hak, and AC impedance study of the electrochemical behavior of hydrogen, Oxygen gas mixture at nafion, catalyst electrode interface by Song, S. M and Lee, W. M.

  7. Still at Odds: The Japanese Abduction Issue and North Korea’s Circumvention

    OpenAIRE

    Anthony DiFilippo

    2013-01-01

    Durante las décadas de 1970 y 1980, Corea del Norte, o tal y como se la conoce oficialmente, la República Democrática Popular de Corea (RDPC), secuestró a una serie de ciudadanos japoneses. Este asunto, hoy por hoy todavía sin resolver, se ha politizado enormemente en Japón, en particular desde que el difunto Kim Jong-Il admitiese al anterior primer ministro japonés, Junichiro Koizumi que efectivamente la RDPC había secuestrado ciudadanos japoneses durante la Guerra Fría. Pyongyang sin embarg...

  8. The role of relA and spoT in Yersinia pestis KIM5 pathogenicity.

    Directory of Open Access Journals (Sweden)

    Wei Sun

    2009-08-01

    Full Text Available The ppGpp molecule is part of a highly conserved regulatory system for mediating the growth response to various environmental conditions. This mechanism may represent a common strategy whereby pathogens such as Yersinia pestis, the causative agent of plague, regulate the virulence gene programs required for invasion, survival and persistence within host cells to match the capacity for growth. The products of the relA and spoT genes carry out ppGpp synthesis. To investigate the role of ppGpp on growth, protein synthesis, gene expression and virulence, we constructed a Delta relA Delta spoT Y. pestis mutant. The mutant was no longer able to synthesize ppGpp in response to amino acid or carbon starvation, as expected. We also found that it exhibited several novel phenotypes, including a reduced growth rate and autoaggregation at 26 degrees C. In addition, there was a reduction in the level of secretion of key virulence proteins and the mutant was > 1,000-fold less virulent than its wild-type parent strain. Mice vaccinated subcutaneously (s.c. with 2.5x10(4 CFU of the Delta relA Delta spoT mutant developed high anti-Y. pestis serum IgG titers, were completely protected against s.c. challenge with 1.5x10(5 CFU of virulent Y. pestis and partially protected (60% survival against pulmonary challenge with 2.0x10(4 CFU of virulent Y. pestis. Our results indicate that ppGpp represents an important virulence determinant in Y. pestis and the Delta relA Delta spoT mutant strain is a promising vaccine candidate to provide protection against plague.

  9. Concept Development of “Nursing Presence”: Application of Schwartz-Barcott and Kim's Hybrid Model

    Directory of Open Access Journals (Sweden)

    Fatemeh Mohammadipour, PhD

    2017-03-01

    Conclusion: Co-constructed interaction underscored the value of the nursing presence as an integral component of caring with humanistic and patient-centered approaches. The findings could help clinical nurses have a better understanding of the nursing presence. Findings also can improve educators' and managers' knowledge for developing and conducting appropriate education strategies and caring activities to facilitate the promotion of nursing presence.

  10. Hlapivi spojevi arome dalmatinske pancete proizvedene u različitim tehnološkim uvjetima

    OpenAIRE

    Krvavica, Marina; Milak, Vedrana

    2017-01-01

    Cilj ovog istraživanja bio je utvrditi u kojoj mjeri razlike u načinu soljenja (sa ili bez aditiva, utrošak soli/salamure, duljina faze soljenja), načinu dimljenja (ložište unutar ili izvan objekta i temperatura dima) te duljina sušenja i zrenja, utječu na sastav hlapivih spojeva arome dalmatinske pancete. U navedenu svrhu uzeta su po 2 uzorka dalmatinske pancete iz dva različita preradbena objekta na području Dalmacije, u kojima je panceta proizvedena na sljedeći način: objekt A – salamurenj...

  11. RAZLIKE U MOTORIČKIM SPOSOBNOSTIMA ODBOJKAŠA I NETRENIRANIH UČENIKA

    Directory of Open Access Journals (Sweden)

    Petar Karadžić

    2011-09-01

    Full Text Available Volleyball is a typical sport of polistructural motion. It is abundant in fast and varied body motions such as jumping, half-roll, rolling and throwing with fast reactions to various situations. This study was conducted with the aim of determining the difference between general motor skills of young volleyball players and untrained boys of the same age. The sample of examinees for this survey was taken from the population of boys aged 15 and 16 years. The experimental group was comprised of 16 male players from VC “Buducnost PB”.. The control group was comprised of 15 eighth grade boys from elementary school "Vuk Karadzic" from Podgorica. Testing of motor abilities in this study was conducted using the following variables: japan test, sargent’s test, standing long jump, throwing a medicine ball from lying position, raising the trunk from the ground, push-ups on the ground, hand taping, and a deep bend on the bench. From the area of comparative parametric statistics, for independent samples, T-test was applied. It was found that between the two groups (trained young volleyball players and their untrained peers in the control group, generally, there is no significant statistical difference in terms of basic motor skills. Statistically significant difference was found only in the test of raising the trunk from the ground which was used to hypothetically evaluate the repetitive potential of abdominal muscles. Only in this test, namely, the realized level of significance was below the theoretical limit (Sig. <.05.. We can assume that volleyball training has an abundance of stimulus that aim on development of abdominal muscles

  12. A Grand Challenge: Immortal Information and Through-Life Knowledge Management (KIM

    Directory of Open Access Journals (Sweden)

    Alexander Ball

    2006-11-01

    Full Text Available ‘Immortal information and through-life knowledge management: strategies and tools for the emerging product-service business paradigm’, is a Grand Challenge project involving eleven different UK universities and incorporating substantial industry collaboration. It is investigating a range of issues associated with the move towards a product-service paradigm in the engineering sector, in particular the long-term curation of digital data, learning from production and use, and appropriate governance and management techniques.

  13. Matematika u vojnotehničkim dostignućima / Mathematics in military-technical achievements

    Directory of Open Access Journals (Sweden)

    Natalija B. Jelenković

    2010-10-01

    Full Text Available Matematika se definiše kao vrsta filozofije ili pogleda na svet, sredstvo za razvijanje apstraktnog mišljenja, a služi i za pojednostavljenje prirodnih nauka. Prilično je specijalna - izučava količinu i poredak; uopšteno, to je nauka o formalnim strukturama. Ona je i kombinacija slobode kreativne misli i strogih logičkih pravila, ali i deduktivna nauka koja daje pravila i zakone pomoću kojih baratamo brojevima i prostorom. Kao takva, matematika je i savremeni alat za vojnotehnička dostignuća modernog doba, kao što su: sve vrste radio i radio-relejnih veza, radarska sredstva, sredstva za upravljanje, navigaciju, televizijska, optoelektronska, hidro- akustična sredstva, sredstva za protivelektronsku borbu, kao i mnoga elektronska tehnička sredstava, naoružanje i vojna oprema Kopnene vojske, Vazduhoplovstva i protiv-vazduhoplovne odbrane, Ratne mornarice. Prethodno istaknute definicije matematike su korišćene kao osnova za uopšteno sistematizovano izlaganje metodom uporednog opisivanja, nabrajanjem činjenica, definisanjem pojmova. Cilj članka je da se na osnovu nabrojanja postojećih primena matematike i proširivanjem znanja može dalje napredovati u istraživanju mnogih vojnih oblasti. Pored toga, članak ima i pedagoški cilj, a to je da kroz opise i karakteristike sredstava ratne tehnike zainteresuje i afirmiše značaj i lepotu vojnog poziva. Rezultati razvoja informacionih tehnologija su, pored ostalog, i savršenija vojnotehnička dostignuća, a predstavljaju i inspiraciju za mnoge inovacije i uspehe. / In this article, mathematics is dealt with as a science necessary for the design, development and implementation of certain military-technical achievements such as many electronic devices, smart missiles, miniature antennas, camouflage military clothing and other military equipment. Some areas of applied, discrete and continuous mathematics are underlined in particular. Application of mathematics The importance of mathematics for military-technical achievements is reflected in the fact that mathematics allowed the existence and development of military disciplines such as: fortifications, military statistics, military economics, cryptography, military psychology, air force, military-technical and military information science. There are also many applications using mathematical models and linear programming. Mathematics is thus necessary and indispensable as a tool, a way of expression and communication, as well as the basic creation of further progress. This article reveals the connection of mathematics and certain military areas that are important for the development of the armed forces and war materiel. The application of mathematics in military- technical achievements is entailed in the connection of mathematics with military disciplines. Information technology - Basic concepts Some identified problems occurring in military purposes are mentioned through some basic concepts and benefits related to information technology. Comparative description and listing of characteristic traits resulting in the noticed and given advantages and disadvantages highlighted the creation of information technologies, first by using conventional programs and programming and then by using artificial intelligence and expert systems.

  14. Systemically applied insecticides for treatment of erythrina gall wasp, quadrastichus erythrinae kim hymenoptera: Eulophidae

    Science.gov (United States)

    Doccola, J.J.; Smith, S.L.; Strom, B.L.; Medeiros, A.C.; Von Allmen, E.

    2009-01-01

    Abstract The erythrina gall wasp (EGW), believed native to Africa, is a recently described species and now serious invasive pest of Erythrina (coral trees) in tropical and subtropical locales. Erythrina are favored ornamental and landscape trees, as well as native members of threatened ecosystems. The EGW is a tiny, highly mobile, highly invasive wasp that deforms (galls) host trees causing severe defoliation and tree death. The first detection of EGW in the United States was in O'ahu, Hawai'i in April 2005. It quickly spread through the Hawai'ian island chain (U.S.) killing ornamental and native Erythrina in as little as two years. At risk are endemic populations of Erythrinaas well as ornamental landscape species in the same genus, the latter of which have already been killed and removed from O'ahu at a cost of more than USD $1 million. Because EGW are so small and spread so quickly, host injury is usually detected before adult wasps are observed, making prophylactic treatments less likely than therapeutic ones. This study evaluates two stem-injected insecticides, imidacloprid (IMA-jet??) and emamectin benzoate, delivered through Arborjet Tree I.V.?? equipment, for their ability to affect E. sandwicensis (wiliwili) canopy demise under severe EGW exposure. IMA-jet, applied at a rate of 0.16 g AI/cm basal diameter (0.4 g AI/in. dia.), was the only effective treatment for maintaining canopy condition of wiliwili trees. Emamectin benzoate, applied at a rate of -0.1 g AI/cm basal diameter (-0.25 g AI/in. dia.), was not effective in this application, although it was intermediate in effect between IMA-jet and untreated trees. The relatively high concentrations of imidacloprid in leaves, and its durability for at least 13 months in native wiliwili growing on a natural, dryland site, suggest that treatment applications against EGW can impact canopy recovery even under suboptimal site and tree conditions. ?? 2009 International Society of Arboriculture.

  15. RAZLIKE U MOTORIČKIM SPOSOBNOSTIMA UČENIKA SPORTISTA I UČENIKA NESPORTISTA

    Directory of Open Access Journals (Sweden)

    Hasim Mekić

    2011-09-01

    Full Text Available Teaching physical education in primary schools takes more character to growing concerns that stem from the personal attitude of the students teaching on the one hand, and poor motivation of teachers due to lack of adequate working conditions for the other. As the official attitude of the community not to allow such a situation, the more we meet with the appearance of lack of justification to continue the spread of pronunciation, and very little to takemeasures to combat such a situation. Testing in sport and physical education, at the present time is the present phenomenon than it was before. Course planned test involves measuring the organized team sports, students in specialized conditions (laboratories. However, testing is a term that includes the daily, routine measurement of results in the function of training process monitoring results as either transverse or longitudinal cross-section of states. Motor skills are one of the psychosomatic status, which expresses the efficiency of motor response and motor behavior of humans. Motor skills are very important part during the building of sports performance in most sports. One part of the motor abilities under significant influence of genetic factors, while the other part subject to the influence of various external factors, especially in sports exercise which is represented in physical education and sports training for children and youth, sports and recreation for adults.

  16. Primena GIS-a u hidrološkim istraživanjima - primer reke Lepenice

    Directory of Open Access Journals (Sweden)

    Milanović Ana

    2007-01-01

    Full Text Available The basic component of GIS technology (Geographical Information Systems is the base of graphical data, which can be used for geographical definition of spaces elements- entities. As a new, modern, technology, it has more application in different hydrological researches. In GIS creation Lepenica river basin, it was applied softwares: Micro Station, GeoMedia, Surfer 7. Map and AutoCAD. After data base creation, it was enabled for users to get different information of Lepenica river basin on the simple way. Getting data are used for creation of three thematic maps (altitude zones map, hydrographical net map and precipitation isoline map.

  17. Dr Jung Hyun KIM Vice Minister for Education, Science and Technology MEST Republic of Korea

    CERN Multimedia

    Jean-Claude Gadmer

    2010-01-01

    He learnt about CERN's LHC computing grid project from Frédéric Hemmer, head of the information technology department. In addition, the vice-minister toured the ATLAS visitor centre, the CMS control centre, the ALICE experiment's exhibition and control room, and he met Korean scientists at CERN.

  18. Obredi i teologija u mistagoškim katehezama Ćirila Jeruzalemskoga

    OpenAIRE

    Mandac, Marijan

    2002-01-01

    U uvodnom dijelu donosi se kratki životopis sv. Ćirila Jeruzalemskoga i prikaz njegovih Mistagoških kateheza kojima se najavljuje hrvatski prijevod. Potom se predstavlja kratak sadržaj svih pet mistagoških kateheza: Prva s obredima odricanja od Sotone, pristajanje uz Krista i ispovijed vjere; Druga s obredom pomazanja i odijevanja posebne krsne odjeće; Treća je posvećena potvrdi i predstavlja nezaobilazno djelo patrističke literature o tome; Četvrta izlaže otajstvo euharistije, a peta tumači ...

  19. RAZLIKE U MOTORIČKIM SPOSOBNOSTIMA UČENIKA SPORTISTA I UČENIKA NESPORTISTA

    OpenAIRE

    Hasim Mekić; Benin Murić; Vladan Milić; Fahrudin Mavrić

    2011-01-01

    Teaching physical education in primary schools takes more character to growing concerns that stem from the personal attitude of the students teaching on the one hand, and poor motivation of teachers due to lack of adequate working conditions for the other. As the official attitude of the community not to allow such a situation, the more we meet with the appearance of lack of justification to continue the spread of pronunciation, and very little to takemeasures to combat such a situation. Test...

  20. Sinise ookeani strateegia : konkurentsi vältimise kunst / W. Chan Kim, Renee Mauborgne

    Index Scriptorium Estoniae

    Kim, W. Chan, 1952-

    2006-01-01

    Sinise ookeani strateegia õpetab, kuidas tegutseda konkurentidest vabal turul. Kommenteerib Hansapanga juhatuse esimees Erkki Raasuke. Lisad: Sinine ookean Tartus; Punane ookean versus sinine ookean. Tabel: Sinise ookeani loomise ajaloost

  1. Lessons learned from 15 years of KIMS and 5 years of ACROSTUDY

    DEFF Research Database (Denmark)

    Luger, Anton; Feldt-Rasmussen, Ulla; Abs, Roger

    2011-01-01

    -deficient adults for 15 years. Approximately 5 years ago, the ACROSTUDY database was established to monitor the long-term safety and effectiveness of pegvisomant in patients with acromegaly. CONCLUSIONS: By collecting data on the treatment of relatively rare conditions in routine clinical practice...

  2. TIP ORGANIZACIJE GRUPE U KOŠARKAŠKIM TIMOVIMA 1. LIGE SRBIJE I CRNE GORE

    Directory of Open Access Journals (Sweden)

    Igor Vučković

    2006-06-01

    Full Text Available In this study were analysed the differences between better placed and worse placed teams of the First basketaball league of Serbia and Montenegro in The type of group organization. The aim was to see in which type of group organization (extrovert or introvert mentioned teams belong, and then to relate it with the final position of their team on the standing. After discriminant analysis it was concluded that there are significant differences between better placed and worse placed teams in The type of group organization with the benefit of the better placed teams.

  3. Type 2-diabetes--en heterogen sygdom med kim i fostertilstanden

    DEFF Research Database (Denmark)

    Vaag, Allan

    2012-01-01

    Type 2 diabetes (T2D) is a heterogeneous disease with a multifactorial aetiology involving defects in the pancreatic beta cells, liver, muscles, adipose tissue, guts, brain, kidneys and heart. While genetics may only explain a minor proportion of T2D, the contribution of an adverse intrauterine...... environment may take centre stage in the global propagation of T2D. Impaired expandability of subcutaneous adipose tissue in persons with low birthweight may cause T2D due to lipotoxicity in non-adipose organs. Future implications include a stronger focus on individualized treatments in T2D patients...

  4. Fluorinated Materials for Air-stable and Moisture-resistant Flexible Optoelectronics

    Science.gov (United States)

    2014-01-02

    Kim Jong , H.; Shin, S.; Yang, H.; An, B.-K.; Yang, L.; Park Soo, Y. Adv Mater 2012, 24, 911-915; (c) Geng, Y.; Li, H.-B.; Wu, S.-X.; Su, Z.-M. J...Park, J.-U.; Shir, D. J.-L.; Nam , Y.-S.; Jeon, S.; Rogers, J. A. Chem. Rev. 2007, 107, 1117-1160; (g) Murphy, A. R.; Frechet, J. M. J. Chem. Rev. 2007...2649-2655; (w) Song, H.-J.; Kim , D.-H.; Lee, E.-J.; Heo, S.-W.; Lee, J.-Y.; Moon, D.-K. Macromolecules (Washington, DC, U. S.) 2012, 45, 7815- 7822; (x

  5. An Introduction to Human Resource Development in Taiwan, R.O.C. = Jong Hwa Min Gwo Ren Li Tz Yuan Fa Jaan Jyan Jieh.

    Science.gov (United States)

    Lee, Lung-Sheng; Chen, Ya-Yan

    In Taiwan, human resource development (HRD) is defined as the systematic education, training, and development employers provide for their employees as well as organizational development for corporations. A history of HRD development indicates that in the 1960s, the government began to implement planning measures for HRD in business and industry;…

  6. Implementation of Genetic Algorithm for Solving De Jong Test Function on Cloud Environment and Compare Its Performance with Local Host Environment

    OpenAIRE

    Syed Tauhid Zuhori

    2012-01-01

    In this day, Cloud Computing has gained large attention not only from IT specialists but also from many clients. It is global network (internet)-based computing, where shared resources, software and information are provided to computers and other devices on-demand, like the electricity bill. Firstly Cost can be reduced and the technology is also known as green saver or power technology. Secondly, the dynamic and flexible scalability of cloud computing. The third is that cloud computing is pla...

  7. Het effect van begeleid rijden (2toDrive) op zelfgerapporteerde ongevallen en overtredingen : een vragenlijstonderzoek onder alle jonge automobilisten in Nederland.

    NARCIS (Netherlands)

    Schagen, I.N.L.G. van Korving, H. & Craen, S. de

    2015-01-01

    The effect of accompanied driving (2toDrive) on self-reported crashes and violations : a questionnaire survey among all young drivers in the Netherlands. In 2011, a six-year accompanied driving pilot under the name of 2toDrive was launched in the Netherlands: young people can get their driving

  8. Het effect van begeleid rijden (2toDrive) op zelfgerapporteerde ongevallen en overtredingen : een vragenlijstonderzoek onder alle jonge automobilisten in Nederland.

    OpenAIRE

    Schagen, I.N.L.G. van Korving, H. & Craen, S. de

    2015-01-01

    The effect of accompanied driving (2toDrive) on self-reported crashes and violations : a questionnaire survey among all young drivers in the Netherlands. In 2011, a six-year accompanied driving pilot under the name of 2toDrive was launched in the Netherlands: young people can get their driving licence B before they are 18 years old, but until their 18th birthday they can only drive while accompanied by an experienced driver. This way they gain more and more varied experience before driving so...

  9. Jong en anders. Onderzoek naar de aandacht voor lesbische, homo, bi-jongeren, transgenderjongeren en jongeren met een intersekse conditie in de jeugdsector

    Directory of Open Access Journals (Sweden)

    Michelle Emmen

    2015-09-01

    Full Text Available Young and different. Research on the attention paid to lesbian, gay, bisexual and transgender youth and young people with an intersex condition in the youth field  Because young LGBT people tend to have worse mental health and become suicidal more often (Kuyper, 2015; Van Bergen & Van Lisdonk, 2010; Kuyper 2015; Collier, Bos & Sandfort 2013; Van Beusekom, Collier, Bos & Sandfort, 2014; Keuzenkamp, 2012, it is to be expected that they are in touch with professionals in the field of youth care more regularly. Hitherto, no research has been conducted into the question of whether LGBT individuals are overrepresented in the field of youth care, so it is unclear whether this is indeed the case. It is also unknown how many individuals with an intersex condition are treated through youth care channels. We do know, however, that there are issues with regard to this target group that are relevant for youth care. These young people are not always registered as such by professionals (Abdallah, De Boer, Bouwens & Bos, 2007; De Boer, Sonneveld, Abdallah, Manesh & Bos, 2009; Felten & Boote, 2012, LGBTi feelings or identity are rarely discussed (Van Denzel, Van Driel & Vondel, 2014, and few professionals take action in the sense of providing for the specific needs, questions and problems on the part of LGBT young people. At the same time, professionals do have questions and learning needs with regard to discussing LGBT issues with individual young people and in groups (Abdallah et al., 2007; JoU, 2013. In 2014, research first took place in the Netherlands into the extent to which professionals working with young people are aware of the existence of, and the specific risks, needs and problems associated with LGBT young people and young people with an intersex condition (Rossenberg, 2013; Van Lisdonk, 2014, and the nature of this awareness. This took the form of a descriptive questionnaire study among 421 professionals, in addition to qualitative input from an expert meeting. The questionnaire was divided into separate questions about lesbian, gay and bisexual young people, questions on transgender youth, and questions on young people with an intersex condition. The questions about the first two groups of young people concern the four themes: registration, discussion, action and learning needs and questions. The questions regarding young people with an intersex condition focus exclusively on registration, since it was expected that professionals do not distinguish between these young people and may even be unaware of the existence of an intersex condition. In the analysis, a chi-squared test was used to look for indications that respondents with specific characteristics would respond differently to the questions. The group of respondents who consider themselves as heterosexual, and the group who indicated that they are gay, lesbian, bisexual, queer, transgender or different, showed significant[1] differences in their responses to parts of the questionnaire. This study shows that professionals’ awareness of and sensitivity to the sexual preferences and gender identity of young people in the youth field is not self-evident. There is a lack of knowledge about these young people: professionals do register LGBT feelings, but do so less often than may be assumed on the basis of figures on the number of LGBTi young people[2]. Nine percent of respondents have never consciously met an LGB young person and 47% have never registered transgender feelings. None of the respondents are familiar with young people with an intersex condition. Some 60% of professionals do not or only rarely discuss assumptions of LGB feelings, while for transgender young people the figure is 71%. Only a minority of professionals act on the LGBT identity of the young person, for instance by focusing on specific LGBT objectives or by referring to specialist care, and 70% never do so with transgender young people. Professionals do not connect LGBT feelings with the other mental and social problems these young people may have: “I find it unnecessary (to discuss LGBT feelings if it’s not a problem”. They do not see LGBT feelings as something special and do not consider that they have a role in supporting young people in discovering and learning to deal with their LGBT feelings. The lack of information on the difficulties experienced by LGBT young people, in combination with an inability to provide adequate support and a lack of direction, cause LGBT young people in the youth field to be overlooked. However, most professionals, 81%, do have questions in this area and need to learn more about the field of LGBTi issues. The fact that professionals see no role for themselves in supporting LGBT young people may be related to the fact that they see an LGBT orientation as “nothing special”. Professionals do not realize that the young people themselves do find it special to discover their own LGB feelings. Usually it takes them a few years before they dare to discuss it with someone else (Kuyper, 2015a; Van Lisdonk & Van Bergen, 2010. It is the same for transgender young people, whose physical gender is not in line with the gender they identify with: that is indeed something special. Professionals tend to reason on the basis of their own tolerant adult perspective and avoid discussing LGBT orientations as something special. This study shows that LGBTi young people very often do not receive the right kind of support. We would like their care to include an acknowledgement of their “being different” and of their specific needs, wishes and problems. This leads us to recommendations on three levels: to municipalities, to organizations in the youth field and to professionals. At the municipal level, it is important to incorporate LGBTi in local policy and in the requirements for calls for tender. Organizations in the field of youth care should include the theme of LGBTi in their diversity policies, and operationalize the issue into suggestions for questions concerning sexual and gender diversity in the intake. At the level of professionals, further research would be useful: action research to determine what kinds of specific competences are needed to support LGBTi young people. Incorporating these competences into the curriculums of universities of applied science will ensure that future professionals know how to support LGBTi young people. SAMENVATTINGJong en anders. Onderzoek naar de aandacht voor lesbische, homo, bi-jongeren, transgenderjongeren en jongeren met een intersekse conditie in de jeugdsectorOmdat LHBT-jongeren een slechtere psychische gezondheid hebben en vaker suïcidaal zijn (Kuyper, 2015; Van Bergen & Van Lisdonk, 2010; Kuyper 2015; Collier, Bos & Sandfort, 2013; Van Beusekom, Collier, Bos & Sandfort, 2014; Keuzenkamp, 2012 ligt het voor de hand dat zij vaker in aanraking komen met professionals in de jeugdsector. In 2014 is voor het eerst in Nederland een onderzoek uitgevoerd naar de mate waarin en op welke manier er onder professionals die werken met jongeren aandacht is voor het bestaan, de specifieke risico’s, behoeften en problemen van LHBT-jongeren en jongeren met een intersekse conditie (Rossenberg, 2013; Van Lisdonk, 2014. Het gaat om een beschrijvend vragenlijstonderzoek onder 421 professionals, aangevuld met kwalitatieve input uit een expertmeeting. Uit de resultaten blijkt dat aandacht van professionals voor seksuele voorkeur en genderidentiteit niet vanzelfsprekend is. Er is sprake van een gebrek aan kennis over deze jongeren: 41% weet niet hoe te signaleren dat een jongere worstelt met LHB-gevoelens en voor transgenderjongeren is dat 64%. Geen van de respondenten ontmoette ooit bewust een jongere met een intersekse conditie. Professionals brengen LHBT-gevoelens niet in verband met andere psychische en sociale problemen die deze jongeren hebben. Zij ervaren LHBT-gevoelens zelf niet als iets bijzonders en zien geen rol voor zichzelf in het ondersteunen van de betreffende jongeren. De combinatie van een gebrek aan kennis van de moeilijkheden die LHBTi-jongeren ervaren en het bestaan van handelingsverlegenheid en een gebrek aan handelingsperspectief zorgt ervoor dat aandacht voor LHBTi-jongeren in de jeugdsector niet vanzelfsprekend is.

  10. Welke soort rood zwenkgras (Festuca rubra s.l.) komt voor in de jonge kustduinen van Voorne en die van overig Nederland?

    NARCIS (Netherlands)

    Freijsen, A.H.J.; Heeres, Els

    1972-01-01

    By common consent two taxa of Festuca rubra s.l. occur in sandy outer dunes along the N.W. European coasts. Festuca juncifolia St. Amans is considered to be a typical grass of Ammophiladunes. Festuca rubra subsp. arenaria (Osb.) Richt. could be found on almost fixed dunes. The only usable character

  11. Effect of zinc oxide nanoparticles on dams and embryo–fetal development in rats

    Directory of Open Access Journals (Sweden)

    Hong J

    2014-12-01

    Full Text Available Jeong-Sup Hong,1,2 Myeong-Kyu Park,1 Min-Seok Kim,1 Jeong-Hyeon Lim,1 Gil-Jong Park,1 Eun-Ho Maeng,1 Jae-Ho Shin,3 Yu-Ri Kim,4 Meyoung-Kon Kim,4 Jong-Kwon Lee,5 Jin-A Park,2 Jong-Choon Kim,6 Ho-Chul Shin2 1Health Care Research Laboratory, Korea Testing and Research Institute, Gimpo, 2College of Veterinary Medicine, Konkuk University, Seoul, 3Department of Biomedical Laboratory Science, Eulji University, Seongnam-si, 4Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, 5Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, 6College of Veterinary Medicine, Chonnam National University, Gwangju, Korea Abstract: This study investigated the potential adverse effects of zinc oxide nanoparticles (ZnOSM20[-] NPs; negatively charged, 20 nm on pregnant dams and embryo–fetal development after maternal exposure over the period of gestational days 5–19 with Sprague Dawley rats. ZnOSM20(- NPs were administered to pregnant rats by gavage at 0 mg/kg/day, 100 mg/kg/day, 200 mg/kg/day, and 400 mg/kg/day. All dams were subjected to caesarean section on gestational day 20, and all the fetuses were examined for external, visceral, and skeletal alterations. Toxicity in the dams manifested as significantly decreased body weight at 400 mg/kg/day and decreased liver weight, and increased adrenal glands weight at 200 mg/kg/day and 400 mg/kg/day. However, no treatment-related difference in the number of corpora lutea, the number of implantation sites, the implantation rate (%, resorption, dead fetuses, litter size, fetal deaths, fetal and placental weights, and sex ratio were observed between the groups. Morphological examinations of the fetuses demonstrated no significant difference in the incidences of abnormalities between the groups. No significant difference was found in the Zn content of fetal tissue between the control and high-dose groups. These results showed

  12. Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation

    Directory of Open Access Journals (Sweden)

    Yoon TH

    2012-03-01

    Full Text Available Ki-Chun Yoo1, Chang-Hwan Yoon1, Dongwook Kwon2, Kyung-Hwan Hyun1, Soo Jung Woo1, Rae-Kwon Kim1, Eun-Jung Lim1, Yongjoon Suh1, Min-Jung Kim1, Tae Hyun Yoon2, Su-Jae Lee11Laboratory of Molecular Biochemistry, 2Laboratory of Nanoscale Characterization and Environmental Chemistry, Department of Chemistry, Hanyang University, Seoul, Republic of KoreaBackground: Titanium dioxide (TiO2 has been widely used in many areas, including biomedicine, cosmetics, and environmental engineering. Recently, it has become evident that some TiO2 particles have a considerable cytotoxic effect in normal human cells. However, the molecular basis for the cytotoxicity of TiO2 has yet to be defined.Methods and results: In this study, we demonstrated that combined treatment with TiO2 nanoparticles sized less than 100 nm and ultraviolet A irradiation induces apoptotic cell death through reactive oxygen species-dependent upregulation of Fas and conformational activation of Bax in normal human cells. Treatment with P25 TiO2 nanoparticles with a hydrodynamic size distribution centered around 70 nm (TiO2P25–70 together with ultraviolet A irradiation-induced caspase-dependent apoptotic cell death, accompanied by transcriptional upregulation of the death receptor, Fas, and conformational activation of Bax. In line with these results, knockdown of either Fas or Bax with specific siRNA significantly inhibited TiO2-induced apoptotic cell death. Moreover, inhibition of reactive oxygen species with an antioxidant, N-acetyl-L-cysteine, clearly suppressed upregulation of Fas, conformational activation of Bax, and subsequent apoptotic cell death in response to combination treatment using TiO2P25–70 and ultraviolet A irradiation.Conclusion: These results indicate that sub-100 nm sized TiO2 treatment under ultraviolet A irradiation induces apoptotic cell death through reactive oxygen species-mediated upregulation of the death receptor, Fas, and activation of the preapoptotic protein

  13. Savremene metode analize ulja u tehničkim sistemima / Modern methods of oil analysis in technical systems

    Directory of Open Access Journals (Sweden)

    Sreten R. Perić

    2010-01-01

    Full Text Available Analiza ulja na osnovu pravilno definisanog programa predstavlja veoma efikasan metod monitoringa stanja tehničkih sistema koji obezbeđuje rane upozoravajuće znake potencijalnih problema, koji vode ka otkazu i zastoju tehničkih sistema. Ova analiza je veoma efikasan alat programa za monitoring stanja tehničkih sistema. Mnogobrojni uređaji i testovi za analizu ulja omogućavaju kvalitetan monitoring i dijagnosticiranje problema koji nastaju u procesu podmazivanja. Korišćenjem programa za analizu motornih ulja: skraćuje se neplanirano vreme otkaza vozila, poboljšava pouzdanost vozila, produžava radni vek motora, optimizira interval zamene ulja i smanjuju troškovi održavanja vozila. / Different technical systems require an appropriate lubricant to be used at an appropriate place, at appropriate time and in appropriate quantity. Determination of technical systems condition has a very important role in the development of theory and practice of friction, wear and lubrication. Lubricant is, as a contact element of tribomechanical systems, a carrier of information about the state of the whole system, from the aspect of tribological and other ageing processes. The analysis of oils, based on a properly defined program, thus represents a very effective method for monitoring the condition of technical systems, which ensures early warning signals of potential problems that could lead to failure and break down of technical systems. Introduction It is not always simple to determine a type of lubricant, frequency of lubrication and the quantity of lubricant to be used. The optimal recommendation would be to follow specifications of technical system manufacturers, experience, lab research or professional recommendation of lubricant suppliers. Rational lubricant consumption can be obtained by timely oil replacement, which then enables a maximum possible period of use as well as high-quality lubrication. Since the primary role of lubricants is to reduce negative effects of tribological processes related to friction, wear and temperature increase in tribomechanical systems, all types of maintenance include lubrication as a very important part of the whole procedure. On the other hand, lubricant is, as a contact element of the system, a carrier of information about the condition of the whole system, from the aspect of tribological and other ageing processes. Therefore, an analysis of oils, based on a properly defined program, represents a very effective method for monitoring the condition of technical systems, which ensures early warning signals of potential problems that could lead to failure and break down of technical systems. Besides mechanical components in a system structure, the condition of lubricant itself is also affected, which leads to a loss of lubricating properties. Contamination and degradation of lubricating oils There are numerous opportunities for contamination and degradation of lubricating oils. Contamination and degradation of oil exploitation cannot be completely prevented, but can be significantly reduced, which is very important both for oil and for a technical system itself. The rate and degree of degradation of oil are proportional to the rate and extent of contamination. It is therefore important to prevent rapid contamination of oil, before and during use. The spectrum of oil contaminants is considerably wide. Any contaminant destructive impact on oil, reducing its physical-chemical and working properties, results in shortening its service life as well as the service life of the technical system in question. During oil exploitation, changes occur in: chemical compositions and properties of base oils, chemical compositions and properties of additives, and consequently chemical compositions of oils in general, as a result of contamination and degradation. The most significant oil contaminants are base oils degradation products, additives degradation products, metal particles as a result of wear processes, solid particles from the environment, water and products of fuel combustion. During the operation the following changes occur: contamination of oil by the products of its own degradation, by products of incomplete combustion of fuel and by contaminants of various origin. The main objectives of the analysis and monitoring of oil exploitation in vehicles The main objectives of the analysis and monitoring of oil exploitation in vehicles are: - analysis of system element wear processes, - analysis of lubricant contamination processes, - monitoring changes in the properties of lubricants in order to optimize the life of system functionality control (penetration of contaminants, temperature and pressure, filter efficiency, etc. and - determining the extent of damage and causes of failure. The analysis of the contents of different metals in lubricants is very important. Metal particles are abrasive, and act as catalysts in oil oxidation. In motor oils, they can originate from additives, wear processes, fuel, air and cooling liquid. Metals from additives may be Zn, Ca, Ba, or Mg and they indicate additive deterioration. Metals originating from wear are: Fe, Pb, Cu, Cr, Al, Mn, Ag, Sn, and they point to increased wear in these systems. The elements originating from cooling liquids are Na and B, and their increased content indicates the penetration of cooling liquid in the lubricant. The increased content of Si or Ca, which originate from the air, points to a malfunction of the air filter. Condition monitoring through oil analysis tests There are many different types of oil analysis tests that are used to evaluate lubricants. The tests must cover three areas: technical system condition, contamination condition, and lubricant condition. From the technical system condition aspect, attention should be paid to the presence of any metal particles in oil and the tendencies in their change. The second focus would be the lubricant condition, especially viscosity change, increase in oxidation, and signs of additive depletion. The third focus would be impurities, where the emphasis should be placed on particle number, water content and metal impurities. Theoretically, oil analyses are divided into three classes. In reality, all three condition-monitoring classes are interrelated and must be considered as a whole. For example, an increase in viscosity could be an indication that a lubricant is oxidizing. But oxidation could be an incorrect conclusion, if there is no indication of an increasing oxidation tendency obtained either by the acid number (AN values analysis or the Fourier Transform-Infrared (FT-IR analysis. Lubricant monitoring enables its refreshing or replacement before serious technical system damage occurs. If damage is noticed in the course of operation, and is caused by impurities or lubricant problems, the technical system condition can be monitored and the system may be shut down immediately to minimize damage. There are the two types of alarms, i.e. warning signs used in oil analysis: absolute and statistical alarms. An effective oil analysis relies on the combination of both types. The warning limit is the absolute alarm. The statistical tendency takes into account variability based on oil sampling and its contamination and represents the standard deviation. The deviation from the normal variability indicates serious problems, which is the first signal for taking action and dealing with the problem. As the deviation tendency approaches the warning limit, oil replacement, oil purification or a system inspection is required. Metal particles content and viscosity or some other parameters can be tested. The normal variability range takes into account minor variations caused by analytical accuracy, sample homogeneity, etc. Statistical alarms, which provide the earliest possible warning without false alarms, are difficult to achieve. The factors such as oil adding or changing, filter changes and a sampling technique can distort the results. The following tests are most frequently used in technical system condition monitoring: - Spectrometric Analysis, - Analytical Ferrography, - Rotrode Filter Spectroscopy (RFS, - Infrared Analysis (FT-IR, - Viscosity, - Total acid number (TAN, - Total Base Number (TBN - Water and Particle Count.

  14. PROMENE KRVNOG PRITISKA U TOKU TESTA FIZIČKIM OPTEREĆENJEM KOD NORMOTENZIVNIH I HIPERTENZIVNIH REKREATIVACA

    Directory of Open Access Journals (Sweden)

    Mirko Šaranović

    2008-08-01

    Full Text Available Background. Arterial hypertension is a leading cause of morbidity in developed countries. It often decreases functional capacities of the cardiovascular system. Changes of pressure during physical exercise are a very significant a prognostic factor. Aim. The aim of this investigation was to assess changes of blood pressure and heart rate during exercise in normotensive and hypertensive men involved in recreational physical activity. Methods. The study included 90 young men (aged 30-40 years involved in recreation (60 with hypertension, 30 with normal pressure. The bicycle ergometer test was performed after rest, the load increased gradually from 50 to 125W. Blood pressure and heart rate were measured at rest and during the exercise. Results. Systolic and diastolic pressure increased signifi cantly in both groups during the ergometry test, compared to the values at rest. This increase was higher among hypertensive men for every graduation of test load (p<0.05. Heart rate was similar in both groups at rest, but higher values were noted among hypertensive men (p<0.05.

  15. Growth of a plasmid-bearing (pYV) Yersinia pestis KIM5 in retail raw ground pork

    Science.gov (United States)

    Yersinia pestis can cause oro-pharyngeal plague as a result of consumption or handling of meat from infected animals. Thus, food naturally or intentionally contaminated can have a role in the dissemination of human plague. The growth of a conditionally virulent plasmid (pYV)-bearing rifampicin-res...

  16. VizieR Online Data Catalog: Low-resolution near-infrared stellar spectra from CIBER (Kim+, 2017)

    Science.gov (United States)

    Kim, M. G.; Lee, H. M.; Arai, T.; Bock, J.; Cooray, A.; Jeong, W.-S.; Kim, S. J.; Korngut, P.; Lanz, A.; Lee, D. H.; Lee, M. G.; Matsumoto, T.; Matsuura, S.; Nam, U. W.; Onishi, Y.; Shirahata, M.; Smidt, J.; Tsumura, K.; Yamamura, I.; Zemcov, M.

    2017-06-01

    We present flux-calibrated near-infrared spectra of 105 stars from 0.8{skin, we do not use the first flight data in this work. The star spectral types are determined by fitting known spectral templates to the measured LRS spectra. We use the Infrared Telescope Facility (IRTF) and Pickles 1998 (Cat. J/PASP/110/863) templates for the SED fitting. The SpeX instrument installed on the IRTF observed stars using a medium-resolution spectrograph (R=2000). The template library contains spectra for 210 cool stars (F to M type) with wavelength coverage from 0.8 to 2.5μm (Cushing 2005ApJ...623.1115C; Rayner 2009ApJS..185..289R). The Pickles library is a synthetic spectral library that combines spectral data from various observations to achieve wavelength coverage from the UV (0.115μm) to the near-infrared (2.5μm). It contains 131 spectral templates for all star types (i.e., O to M type) with a uniform sampling interval of 5Å. (6 data files).

  17. Estimation of spawning area of Pisodonophis sangjuensis Ji and Kim, 2011 (Pisces: Ophichthidae) based on leptocephali size and distribution

    Science.gov (United States)

    Ji, Hwan-Sung; Hwang, Kangseok; Choi, Jung Hwa; Cha, Hyung-Kee; Kim, Jin-Koo

    2017-06-01

    Pre-metamorphic leptocephali of Pisodonophis sangjuensis ( n = 91, 10.4-90.2 mm in total length, TL) were collected in the East China Sea for the first time. Pre-metamorphic leptocephali of P. sangjuensis, which were identified using mitochondrial DNA cytochrome c oxidase subunit I gene (mtDNA COI), are characterized by various combinations of morphological characters: 8 moderate to pronounced gut loops with the kidney terminating on the 6-7th loops; and 8 subcutaneous pigment patches on the tail just ventral to the notochord. Pisodonophis sangjuensis leptocephali were more numerously collected offshore than inshore around Jeju Island. The smallest leptocephali ( 100.0 mm TL) were collected from around Jeju Island and the southern coast of Korea. Our findings indicate that P. sangjuensis spawns offshore south of Jeju Island that is an area associated with high water temperature, and then the hatched leptocephali are transported to Jeju Island or the southern coast of Korea by the Tsushima Warm Current.

  18. Support for harmful treatment and reduction of empathy toward blacks: "Remnants" of stereotype activation involving Hurricane Katrina and "Lil' Kim"

    NARCIS (Netherlands)

    Johnson, J.D.; Bushman, B.J.

    2008-01-01

    Two experiments involving White participants tested the influence of media-based Black stereotypes on subsequent responses to Black and White persons-in-need. Experiment 1 showed that priming the "Black criminal" stereotype through exposure to photographs of Blacks looting after Hurricane Katrina

  19. Report on the Second KIMS-CNA Conference: The PLA Navys Build-Up and ROK-USN Cooperation

    Science.gov (United States)

    2009-02-01

    Modernization (London and Washington, DC: Kegan Paul International and The AEI Press, 1996), p. 274. See also his “China’s Push Through the South China Sea...to change its nature of the PLA Navy naval strategy from “brown water” force to “ green /blue water” navy enable to secure its vast maritime...and “full ocean-going green water fleet.” It is conceivable that the Chinese navy’s goal of its operational capability is not “blue water navy,” but

  20. VizieR Online Data Catalog: ChaMP X-ray point source catalog (Kim+, 2007)

    Science.gov (United States)

    Kim, M.; Kim, D.-W.; Wilkes, B. J.; Green, P. J.; Kim, E.; Anderson, C. S.; Barkhouse, W. A.; Evans, N. R.; Ivezic, Z.; Karovska, M.; Kashyap, V. L.; Lee, M. G.; Maksym, P.; Mossman, A. E.; Silverman, J. D.; Tananbaum, H. D.

    2009-01-01

    We present the Chandra Multiwavelength Project (ChaMP) X-ray point source catalog with ~6800 X-ray sources detected in 149 Chandra observations covering ~10deg2. The full ChaMP catalog sample is 7 times larger than the initial published ChaMP catalog. The exposure time of the fields in our sample ranges from 0.9 to 124ks, corresponding to a deepest X-ray flux limit of f0.5-8.0=9x10-16ergs/cm2/s. The ChaMP X-ray data have been uniformly reduced and analyzed with ChaMP-specific pipelines and then carefully validated by visual inspection. The ChaMP catalog includes X-ray photometric data in eight different energy bands as well as X-ray spectral hardness ratios and colors. To best utilize the ChaMP catalog, we also present the source reliability, detection probability, and positional uncertainty. (10 data files).

  1. VizieR Online Data Catalog: NIR polarimetric study in the LMC N159/N160 field (Kim+, 2017)

    Science.gov (United States)

    Kim, J.; Jeong, W.-S.; Pyo, J.; Pak, S.; Park, W.-K.; Kwon, J.; Tamura, M.

    2018-04-01

    Simultaneous JHKs polarimetric observations of the N159/N160 c were performed on 2007 February 3 and 5. We used the near-infrared camera SIRIUS (Nagayama et al. 2003SPIE.4841..459N) and the polarimeter SIRPOL (Kandori et al. 2006SPIE.6269E..51K) of the Infrared Survey Facility (IRSF) 1.4 m telescope at the South African Astronomical Observatory in Sutherland, South Africa. The camera has a field of view of 7.7"x7.7" and a pixel scale of 0.45"/pixel. One set of observations for a target field consisted of 20 s exposures at 10 dithered positions for four wave-plate angles (0°, 45°, 22.5°, and 67.5°) in the J, H, and Ks bands, and the whole sequence is repeated 10 and 9 times for the N159 and N160 fields centered at (α, δ)2000=(5h39m37.1s, -69°43'45.1") and (5h40m05.6s, -69°36'25.8"), respectively. (2 data files).

  2. ANALYSIS OF CORNEAL ASTIGMATISM BEFORE AND AFTER PTERYGIUM SURGERY- A PROSPECTIVE STUDY IN PATIENTS ATTENDING KIMS, HUBLI

    Directory of Open Access Journals (Sweden)

    Y. B. Bajantri

    2017-10-01

    Full Text Available BACKGROUND Pterygium is a very common degenerative condition seen in Indian subcontinent. It is a wing-shaped fibrovascular encroaching up on the cornea from either sides. The prevalence rate is 5.2%. Pterygium is known to affect refractive astigmatism. The induced astigmatism may become significant to cause visual distortion, even though the pterygium remains distant from visual axis induced astigmatism maybe either “with-the-rule” or “against-the-rule.” The aim of the study is to- 1. Compare preoperative with postoperative astigmatism in case of pterygium. 2. Assess the amount of astigmatism in case of pterygia of different lengths measured from the limbus over the cornea. MATERIALS AND METHODS The study included 70 eyes of 70 patients with primary pterygium. Preoperative evaluation included pterygium size, visual acuity, keratometry and refraction with subjective correction. Patients included in the study were divided into three groups based on length of pterygium encroaching on cornea (1 to 2 mm, 2 to 3 mm, >3 mm. Each eye underwent bare sclera pterygium excision. Postoperative visual acuity, keratometry and refraction were evaluated on 1st day, at the end of 1st week, 4 th week and 9th week. The pre and postoperative results were compared and analysed. RESULTS An average of all 70 cases with mean pterygium length 3.2 mm had a mean keratometry astigmatism of 1.84 ± 0.89D preoperatively and 0.514 ± 0.52D postoperatively indicating a reduction of pterygium-induced corneal astigmatism by 1.45 ± 0.77D (p value <0.0001, which was statistically significant. CONCLUSION Pterygium-induced corneal astigmatism is directly proportional to the size of the pterygium. Thus, early surgical excision reduces the corneal astigmatism, and hence, improves the visual acuity.

  3. Subsurface temperature estimation from climatology and satellite SST for the sea around Korean Peninsula 1Bong-Guk, Kim, 1Yang-Ki, Cho, 1Bong-Gwan, Kim, 1Young-Gi, Kim, 1Ji-Hoon, Jung 1School of Earth and Environmental Sciences, Seoul National University

    Science.gov (United States)

    Kim, Bong-Guk; Cho, Yang-Ki; Kim, Bong-Gwan; Kim, Young-Gi; Jung, Ji-Hoon

    2015-04-01

    Subsurface temperature plays an important role in determining heat contents in the upper ocean which are crucial in long-term and short-term weather systems. Furthermore, subsurface temperature affects significantly ocean ecology. In this study, a simple and practical algorithm has proposed. If we assume that subsurface temperature changes are proportional to surface heating or cooling, subsurface temperature at each depth (Sub_temp) can be estimated as follows PIC whereiis depth index, Clm_temp is temperature from climatology, dif0 is temperature difference between satellite and climatology in the surface, and ratio is ratio of temperature variability in each depth to surface temperature variability. Subsurface temperatures using this algorithm from climatology (WOA2013) and satellite SST (OSTIA) where calculated in the sea around Korean peninsula. Validation result with in-situ observation data show good agreement in the upper 50 m layer with RMSE (root mean square error) less than 2 K. The RMSE is smallest with less than 1 K in winter when surface mixed layer is thick, and largest with about 2~3 K in summer when surface mixed layer is shallow. The strong thermocline and large variability of the mixed layer depth might result in large RMSE in summer. Applying of mixed layer depth information for the algorithm may improve subsurface temperature estimation in summer. Spatial-temporal details on the improvement and its causes will be discussed.

  4. Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride

    Directory of Open Access Journals (Sweden)

    Baek I

    2015-06-01

    Full Text Available In-hwan Baek,1,* Eun-Sol Ha,2,* Jin-Wook Yoo,2 Yunjin Jung,2 Min-Soo Kim21College of Pharmacy, Kyungsung University, 2College of Pharmacy, Pusan National University, Busan, Republic of Korea*These authors contributed equally to this workAbstract: In this study, a gelatin microparticle-containing self-microemulsifying formulation (SMF was developed using a spray-drying method to enhance the oral delivery of the poorly water-soluble therapeutic dutasteride. The effect of the amount of gelatin and the type and amount of hydrophilic additives, namely, Gelucire® 44/14, poloxamer 407, sodium lauryl sulfate, Soluplus®, Solutol™ HS15, and D-α-tocopheryl polyethylene glycol 1000 succinate, on the droplet size, dissolution, and oral absorption of dutasteride from the SMF was investigated. Upon dispersion of the gelatin microparticle-containing SMF in water after spray-drying, the mean droplet size of the aqueous dispersion was in the range of 110–137 nm. The in vitro dissolution and recrystallization results showed that gelatin could be used as a solid carrier and recrystallization inhibitor for the SMF of dutasteride. Furthermore, combination of the gelatin microparticle-containing SMF and Soluplus enhanced the dissolution properties and oral absorption of dutasteride. The results of our study suggest that the gelatin microparticle-containing SMF in combination with Soluplus could be useful to enhance the oral absorption of dutasteride.Keywords: dissolution, solubility, bioavailability, dutasteride

  5. Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization

    Directory of Open Access Journals (Sweden)

    Ha ES

    2015-06-01

    Full Text Available Eun-Sol Ha,1 In-hwan Baek,2 Jin-Wook Yoo,1 Yunjin Jung,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2College of Pharmacy, Kyungsung University, Busan, Republic of Korea Abstract: The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubility measurements, surface-modified pranlukast hemihydrate microparticles were manufactured using the spray-drying method with hydroxypropylmethyl cellulose, sucrose laurate, and water and without the use of an organic solvent. The hydrophilicity of the surface-modified pranlukast hemihydrate microparticle increased, leading to enhanced dissolution and oral bioavailability of pranlukast hemihydrate without a change in crystallinity. The surface-modified microparticles with an hydroxypropylmethyl cellulose/sucrose laurate ratio of 1:2 showed rapid dissolution of up to 85% within 30 minutes in dissolution medium (pH 6.8 and oral bioavailability higher than that of the commercial product, with approximately 2.5-fold and 3.9-fold increases in area under the curve (AUC0→12 h and peak plasma concentration, respectively. Therefore, the surface-modified microparticle is an effective oral drug delivery system for the poorly water-soluble therapeutic pranlukast hemihydrate. Keywords: solubility, wettability, sucrose laurate, cellulose

  6. USA og Kina lægger med forskellig strategi an til forhandlinger med Nordkorea

    DEFF Research Database (Denmark)

    Nørup Sørensen, Camilla Tenna

    2017-01-01

    Der har de seneste uger været en massiv dækning i danske medier af Nordkorea og det lukkede lands bestræbelser på at udvikle langtrækkende missiler og atomvåben. Der har ikke været mangel på dommedagsscenarier og fremstillinger af den nordkoreanske leder Kim Jong-Un som en irrationel og uberegnel......, er også gået lige ind hjulpet ekstra på vej af USA’s angreb i Syrien, som foregik, mens Trump havde den kinesiske præsident Xi Jinping til middag i Florida. Men er der egentlig så meget nyt?...

  7. North Korea, Quo Vadis?

    Directory of Open Access Journals (Sweden)

    Karl H. Stingeder

    2014-03-01

    Full Text Available North Korean politics appears neither irrational nor unpredictable: the logic of its actions may at first seem opaque, but it nonetheless displays its own rationale and patterns. – North Korea: a ruthless political actor, now under the leadership of Kim Jong-Un who inherited the regime’s leadership from his father and "Supreme Leader", Kim Jong-Il, in 2011. The country’s policy is based on its ongoing political agenda of (nuclear brinkmanship, a true threat to the world – or at least that's how the Western hemisphere sees it. Yet our factual knowledge of this post-Leninist and totalitarian regime is extremely limited and relatively distorted; it is largely circumstantial evidence and judgmental speculation that accounts for our perception of this East Asian state. Northeast Asia (China, Japan, South and North Korea, Taiwan is a region dominated by the legacy of the Cold War. The North Korean leadership has indeed established its priorities, primarily its isolationist orientation, but in the long term the regime cannot survive without external stimulus. Most importantly, even in a long-term, non-violent and gradual transformation of North Korea considerable danger can ultimately result in the demise of the regime. Apart from few signs of a North Korean "civil society", currently only the army might have the resources to see through a regime change. In the meantime, the strategies of isolationism as well as tight control of the media remain as fundamental cornerstones of the regime. A close-knit network of social control has been established and access to the internet for the most part is limited to the regime’s entrusted cadre.

  8. Development and validation of the Pictorial Cognitive Screening Inventory for illiterate people with dementia

    Directory of Open Access Journals (Sweden)

    Park S

    2014-09-01

    Full Text Available Soowon Park,1,* Se-Eun Park,1,* Min-Ji Kim,2 Hee-Yeon Jung,1,2 Jung-Seok Choi,1,2 Kee-Hwan Park,3 Inhye Kim,1 Jun-Young Lee1,2 1Department of Neuropsychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea; 2Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Department of Psychology, The Catholic University of Korea, Bucheon, Republic of Korea *These authors contributed equally to this work Purpose: The purpose of this study was to develop and validate a tool called the Pictorial Cognitive Screening Inventory (PCSI, which consists of pictorial memory and attention tests that are not influenced by literacy level.Patients and methods: PCSI, Mini Mental State Examination (MMSE, and Clinical Dementia Rating (CDR questionnaires were administered to 80 elderly participants (20 illiterate normal, 20 illiterate with dementia, 20 literate normal, and 20 literate with dementia.Results: PCSI scores were highly correlated with those of the MMSE (r 0.51 and the CDR (r -0.71. In addition, the PCSI scores differed significantly between the normal group and the dementia group (mean difference 1.71, standard error [SE] 0.14, P<0.001, while no such difference was observed between the illiterate group and the literate group (mean difference 0.00, SE 0.24, P=0.997. Diagnostic validity of the PCSI is excellent, with a sensitivity of 90% and a specificity of 98% for screening dementia, whereas the MMSE has a sensitivity of 85% and a specificity of 60%.Conclusion: These results indicate that the PCSI is a sensitive and reliable test for screening dementia, regardless of an individual’s literacy skills. The PCSI meets the increasing needs for screening of dementia in illiterate elderly populations in developing countries. Keywords: screening, dementia, literacy, cognition 

  9. Prenatal development toxicity study of zinc oxide nanoparticles in rats

    Directory of Open Access Journals (Sweden)

    Hong JS

    2014-12-01

    Full Text Available Jeong-Sup Hong,1,2 Myeong-Kyu Park,1 Min-Seok Kim,1 Jeong-Hyeon Lim,1 Gil-Jong Park,1 Eun-Ho Maeng,1 Jae-Ho Shin,3 Meyoung-Kon Kim,4 Jayoung Jeong,5 Jin-A Park,2 Jong-Choon Kim,6 Ho-Chul Shin2 1Health Care Research Laboratory, Korea Testing and Research Institute, Gimpo, South Korea; 2College of Veterinary Medicine, Konkuk University, Seoul, South Korea; 3Department of Biomedical Laboratory Science, Eulji University, Seongnam-si, South Korea; 4Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea; 5Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungcheongbuk-do, South Korea; 6College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea Abstract: This study investigated the potential adverse effects of zinc oxide nanoparticles ([ZnOSM20(+ NPs] zinc oxide nanoparticles, positively charged, 20 nm on pregnant dams and embryo–fetal development after maternal exposure over the period of gestational days 5–19 with Sprague-Dawley rats. ZnOSM20(+ NPs were administered to pregnant rats by gavage at 0, 100, 200, and 400 mg/kg/day. All dams were subjected to a cesarean section on gestational day 20, and all of the fetuses were examined for external, visceral, and skeletal alterations. Toxicity in the dams manifested as significantly decreased body weight after administration of 400 mg/kg/day NPs; reduced food consumption after administration of 200 and 400 mg/kg/day NPs; and decreased liver weight and increased adrenal glands weight after administration of 400 mg/kg/day NPs. However, no treatment-related difference in: number of corpora lutea; number of implantation sites; implantation rate (%; resorption; dead fetuses; litter size; fetal deaths and placental weights; and sex ratio were observed between the groups. On the other hand, significant decreases between treatment groups and controls were seen for fetal weights after

  10. Enzyme-responsive doxorubicin release from dendrimer nanoparticles for anticancer drug delivery

    Directory of Open Access Journals (Sweden)

    Lee SJ

    2015-08-01

    Full Text Available Sang Joon Lee,1,* Young-Il Jeong,2,* Hyung-Kyu Park,3 Dae Hwan Kang,2,4 Jong-Suk Oh,3 Sam-Gyu Lee,5 Hyun Chul Lee31Department of Biomedical Sciences, Chonnam National University Medical School, Gwangju, 2Biomedical Research Institute, Pusan National University Hospital, Busan, 3Department of Microbiology, Chonnam National University Medical School, Gwangju, 4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongnam, 5Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea*These authors contributed equally to this workBackground: Since cancer cells are normally over-expressed cathepsin B, we synthesized dendrimer-methoxy poly(ethylene glycol (MPEG-doxorubicin (DOX conjugates using a cathepsin B-cleavable peptide for anticancer drug targeting.Methods: Gly-Phe-Leu-Gly peptide was conjugated with the carboxylic acid end groups of a dendrimer, which was then conjugated with MPEG amine and doxorubicin by aid of carbodiimide chemistry (abbreviated as DendGDP. Dendrimer-MPEG-DOX conjugates without Gly-Phe-Leu-Gly peptide linkage was also synthesized for comparison (DendDP. Nanoparticles were then prepared using a dialysis procedure.Results: The synthesized DendGDP was confirmed with 1H nuclear magnetic resonance spectroscopy. The DendDP and DendGDP nanoparticles had a small particle size of less than 200 nm and had a spherical morphology. DendGDP had cathepsin B-sensitive drug release properties while DendDP did not show cathepsin B sensitivity. Further, DendGDP had improved anticancer activity when compared with doxorubicin or DendDP in an in vivo CT26 tumor xenograft model, ie, the volume of the CT26 tumor xenograft was significantly inhibited when compared with xenografts treated with doxorubicin or DendDP nanoparticles. The DendGDP nanoparticles were found to be relatively concentrated in the tumor tissue and

  11. Leidlikud lahendused : uus elamuehitus Amsterdamis = Enforcing Ingenuity New Housing in Amsterdam / Hans Ibelings ; hollandi keelest tõlk. eesti keelde Katrin Laiapea ja inglise keelde Robyn de Jong-Dalziel

    Index Scriptorium Estoniae

    Ibelings, Hans

    2001-01-01

    Amsterdami kahe elamurajooni planeeringust. Borneo-Sporenburgi (1994-2001) planeeringu tegi Adriaan Geuze ja tema büroo West 8. Kolm hiigelelamut projekteerisid Koen van Velsen, Frits van Dongen ja Kees Christiaanse. Valmimisjärgus IJburgi planeeringu autorid Felix Claus, Frits van Dongen ja Ton Schaap. 13 ill

  12. The Role of Designated Driver Programs in the Prevention of Alcohol-Impaired Driving: A Critical Reassessment [and] Designated Driver Programs: A Commentary on the DeJong and Wallack Article.

    Science.gov (United States)

    DeJong, William; And Others

    1992-01-01

    Focus on the designated driver strategy by broadcasters and the alcohol industry deflects attention from other alcohol-related problems and the factors influencing underage alcohol consumption. Strategies should emphasize sobriety checkpoints, no sales to minors, advertising reform, and excise taxes on alcohol. (SK)

  13. "Als het bedrijf er maar niet teveel last van heeft" : de invloed van het ouderschapsbeleid en de ouderschapscultuur van supermarkten en boekhandels op de combinatieproblemen van mannelijke en vrouwelijke werknemers met jonge kinderen

    NARCIS (Netherlands)

    Veenis, E.

    2000-01-01

    What impact do businesses have on the efforts of parents with young children who combine work and family, and what factors within the business play a role in this? This was the principal question in this comparative case study of two retailers, a large supermarket chain and a small group of

  14. The prevalence of musculoskeletal disorders and occupational risk factors in Kashan SAIPA automobile industry workers by key indicator method (KIM), 1390

    OpenAIRE

    2012-01-01

    Introduction: work related musculoskeletal disorders are the most wide spread type of occupational diseases among workers. Awkward body postures during work and manual material handling are among the most important risk factors of musculoskeletal disorders in different jobs. Due to importance of recognizing these factors prevalence and risk factor of work related musculoskeletal disorders, this research was aimed to study the among employees of Kashan City’s Saipa automobile industry in 2...

  15. First experience under the exemption regime of EC Regulation 1228/2003 on Conditions for Access to the Network of Cross-Border Exchanges in Electricity / Kim Talus

    Index Scriptorium Estoniae

    Talus, Kim

    2005-01-01

    23. aprillil 2005 Euroopa Komisjoni poolt vastu võetud otsusest anda roheline tuli Estlink'i projektile, mis tähendab koostööd Eesti ja Soome elektrivõrkude vahel ; Euroopa Komisjon võttis aluseks regulatsiooni nr. 1228/2003 artikli 7

  16. Whole-genome sequencing reveals that Shewanella haliotis Kim et al. 2007 can be considered a later heterotypic synonym of Shewanella algae Simidu et al. 1990.

    Science.gov (United States)

    Szeinbaum, Nadia; Kellum, Cailin E; Glass, Jennifer B; Janda, J Michael; DiChristina, Thomas J

    2018-04-01

    Previously, experimental DNA-DNA hybridization (DDH) between Shewanellahaliotis JCM 14758 T and Shewanellaalgae JCM 21037 T had suggested that the two strains could be considered different species, despite minimal phenotypic differences. The recent isolation of Shewanella sp. MN-01, with 99 % 16S rRNA gene identity to S. algae and S. haliotis, revealed a potential taxonomic problem between these two species. In this study, we reassessed the nomenclature of S. haliotis and S. algae using available whole-genome sequences. The whole-genome sequence of S. haliotis JCM 14758 T and ten S. algae strains showed ≥97.7 % average nucleotide identity and >78.9 % digital DDH, clearly above the recommended species thresholds. According to the rules of priority and in view of the results obtained, S. haliotis is to be considered a later heterotypic synonym of S. algae. Because the whole-genome sequence of Shewanella sp. strain MN-01 shares >99 % ANI with S. algae JCM 14758 T , it can be confidently identified as S. algae.

  17. Acceptance of Gold Medal From the Catalan Society of Transplantation by Drs. Lorraine Racusen and Kim Solez - With Remarks on the Banff Meeting Spirit.

    Science.gov (United States)

    Racusen, L C; Solez, K

    2017-12-01

    The awarding of the gold medal from the Catalan Society of Transplantation to the organizers of the Banff Transplant Pathology meetings is an opportunity to acknowledge gratitude to all the people who have helped make these meetings a success over the past 26 years. Other large organizations have given up consensus conferences, but the Banff consensus process is thriving. It is unusual for any organization to have the same leadership for 26 years. It has only worked for the Banff meetings because the leadership was flexible and able to change with the times. People have often talked about the "special Banff spirit." This year's meeting gave us the opportunity to examine this spirit in detail by analyzing how the meeting consensus sessions and social events functioned. The meeting has never used expert facilitators, but instead has employed experts within the transplant pathology community to moderate discussions. The size of the working sessions is important; they have usually been less than 150 people, which is within "Dunbar's number," meaning that in gatherings of that size one can have empathetic feeling for all the people there. In larger gatherings one loses that "we are all in this together" feeling and people begin thinking "us" versus "them" thoughts. For "unknown" young people the ability to easily talk to well-known leaders in the field is rewarding and keeps them coming back for more time after time. Images of the social events do not suggest any sort of hierarchy; everyone interacts with everyone else. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  18. A. Kim, k.f. Anderson, j. Berliner, j. Hassan, j. Jensen, h.j. Mertz, h. Pietsch, a. Rao, R. Scherer, and a. Sutterfield.

    Science.gov (United States)

    Kim, A; Anderson, K F; Berliner, J; Hassan, J; Jensen, J; Mertz, H J; Pietsch, H; Rao, A; Scherer, R; Sutterfield, A

    2003-10-01

    In this study, three dummies were evaluated on the component level and as a whole. Their responses were compared with available volunteer and embalmed Post Mortem Human Subject (PMHS) data obtained under similar test conditions to evaluate their biofidelity. The volunteer and PMHS data, used as comparators in this study, were used previously to establish some of the biofidelity requirements of the Hybrid III. The BioRID II, the Hybrid III, and the RID2 were all subjected to rear impact HYGE sled tests with deltaVs of 17 and 28 km/hr to determine their biofidelity in these conditions. A static pull test, where a load was manually applied to the head of each dummy, was used to evaluate the static strength of their necks in flexion and extension. Finally, pendulum tests were conducted with the Hybrid III and RID2 to evaluate the dynamic characteristics of their necks in flexion and extension. The sled test results indicate that out of the three dummies, the overall flexibility of the Hybrid III is comparable to that of the volunteer anticipating the impact. The overall flexibilities of the BioRID II and the RID2 are greater than those of all the comparators used in this study (the tensed volunteer and the two embalmed PMHSs). The responses of the Hybrid III are closer to those of the tensed volunteer than those of the PMHSs. The responses of the BioRID II and the RID2 are closer to those of the PMHSs than to the tensed volunteer.

  19. RAZLIKE U NEKIM MOTORIČKIM SPOSOBNOSTIMA KOD UČENIKA OBUHVAĆENIM NASTAVNIM I VANNASTAVNIM AKTIVNOSTIMA IZ KOŠARKE

    Directory of Open Access Journals (Sweden)

    Miodrag Kocić

    2005-05-01

    Full Text Available The aim of this research was to determine the effects that the third class of physical education during one term had on the mobility of the students tested. 101 students, who were divided into two groups, took part in the research. The first group, which was the control group, was made up of 50 students and the second group was made up of the remaining 51 students who were members of the basketball section. The system for measuring mobility encompassed six different disciplines: the high jump, 20 meters high start race, pull-ups, press-ups, forward bend (and lifting the upper part of the body on the bench. All the results of the research were processed in a usual way giving the information on central and dispersion statistics for all disciplines. The differences between the groups were determined by discriminative analysis

  20. Upotreba Kaizen filozofije u upravljačkim strukturama kompanija u Srbiji / The Use of Keizen Philosophy in the Managing Structures in the Companies in Serbia

    Directory of Open Access Journals (Sweden)

    Simona Žikić

    2016-11-01

    Full Text Available In the moment when there is a question mark over the economy of every country and the markets are not stable, but ever changing, moving forward, and/or collapsing, one of the most successful approaches to the survival and improvement of the management of the companies is Keizen concept. Keizen concept of management is philosophy that is initially used in Japan, where it comes from, but in other places all around the world as well, mostly in America and the countries in Western civilization. Keizen philosophy is the concept of continuous improvement, which, strategically observed, contributes improvement and prosperity of the companies. Having in mind its occurrence, the first results of Keizen philosophy’s approach can be identified in the development of Japanese economy, which reached unbelievable results and improvement only few years after the Second World War. Japanese companies very soon became competitive at the global market thanks to Kaizen philosophy, no matter the fact that his approach includes managing concepts and concepts of business organization which are diametrically opposite to the current dominant opinion and application of the concepts of managing business organization from the Western companies. This is the reason why the idea of this paper is to show the main values that are in the core of Kaizen philosophy and to show that the application of this business  concept is possible in Serbia, besides the small number of those who already did it. The aim of this paper is to bring closer the importance of the development of human resources and their influence on the structure of the companies’ management, because only with the human resources department based well, there is a possibility of Keizen philosophy application.

  1. Introductory Statement by Won-Soo Kim [International Conference on Nuclear Security: Commitments and Actions, Vienna (Austria), 5-9 December 2016

    International Nuclear Information System (INIS)

    Kim, Won-Soo

    2017-01-01

    We need to treat WMD risks and threats holistically. Lessons learned in one area can be emulated in another. The IAEA has learned valuable lessons through its own emergency management work and partnership with other UN agencies, including through the UN Counter-Terrorism Implementation Task Force. These lessons could be beneficial in developing response mechanisms for biological incidents.

  2. Analisis Kandungan Timbal (Pb) Dan Kadmium (Cd) Pada Kangkung Air (Ipomoea aquatica Forssk) DAN kangkung Darat (Ipomoea reptans Poir) Di Daerah Mabar-Kim Secara Spektrofotometri Serapan Atom

    OpenAIRE

    Sari, Arisa Dian

    2011-01-01

    Kangkung is a kind of vegetables that is commonly consumed by people and it contains a lot of vitamin A. Surrounding the Industry Area in Medan such as Mabar, vegetables are planted by people, one of them is kangkung. Since the industries growth in the area of the vegetables are expanded, it is wondered that the kangkung has been contaminated by lead and cadmium metals. The purpose of this research is to know the lead and cadmium metals of water kangkung and land kangkung planted in Mabar the...

  3. Analysis of zinc oxide nanoparticles binding proteins in rat blood and brain homogenate

    Directory of Open Access Journals (Sweden)

    Shim KH

    2014-12-01

    Full Text Available Kyu Hwan Shim,1 John Hulme,1 Eun Ho Maeng,2 Meyoung-Kon Kim,3 Seong Soo A An1 1Department of Bionano Technology, Gachon Medical Research Institute, Gachon University, Sungnam-si, Gyeonggi-do, South Korea; 2Department of Analysis, KTR, Kimpo, Gyeonggi-do, South Korea; 3Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea Abstract: Nanoparticles (NPs are currently used in chemical, cosmetic, pharmaceutical, and electronic products. Nevertheless, limited safety information is available for many NPs, especially in terms of their interactions with various binding proteins, leading to potential toxic effects. Zinc oxide (ZnO NPs are included in the formulation of new products, such as adhesives, batteries, ceramics, cosmetics, cement, glass, ointments, paints, pigments, and supplementary foods, resulting in increased human exposures to ZnO. Hence, we investigated the potential ZnO nanotoxic pathways by analyzing the adsorbed proteins, called protein corona, from blood and brain from four ZnO NPs, ZnOSM20(-, ZnOSM20(+, ZnOAE100(-, and ZnOAE100(+, in order to understand their potential mechanisms in vivo. Through this study, liquid chromatography–mass spectroscopy/mass spectroscopy technology was employed to identify all bound proteins. Totals of 52 and 58 plasma proteins were identified as being bound to ZnOSM20(- and ZnOSM20(+, respectively. For ZnOAE100(- and ZnOAE100(+, 58 and 44 proteins were bound, respectively. Similar numbers of proteins were adsorbed onto ZnO irrespective of size or surface charge of the nanoparticle. These proteins were further analyzed with ClueGO, a Cytoscape plugin, which provided gene ontology and the biological interaction processes of identified proteins. Interactions between diverse proteins and ZnO nanoparticles could result in an alteration of their functions, conformation, and clearance, eventually affecting many biological processes. Keywords: brain

  4. Entrapment of curcumin into monoolein-based liquid crystalline nanoparticle dispersion for enhancement of stability and anticancer activity

    Directory of Open Access Journals (Sweden)

    Baskaran R

    2014-06-01

    Full Text Available Rengarajan Baskaran,1 Thiagarajan Madheswaran,2 Pasupathi Sundaramoorthy,1 Hwan Mook Kim,1 Bong Kyu Yoo1 1College of Pharmacy, Gachon University, Incheon, South Korea; 2College of Pharmacy Yeungnam University, Gyeongsan, South Korea Abstract: Despite the promising anticancer potential of curcumin, its therapeutic application has been limited, owing to its poor solubility, bioavailability, and chemical fragility. Therefore, various formulation approaches have been attempted to address these problems. In this study, we entrapped curcumin into monoolein (MO-based liquid crystalline nanoparticles (LCNs and evaluated the physicochemical properties and anticancer activity of the LCN dispersion. The results revealed that particles in the curcumin-loaded LCN dispersion were discrete and monodispersed, and that the entrapment efficiency was almost 100%. The stability of curcumin in the dispersion was surprisingly enhanced (about 75% of the curcumin survived after 45 days of storage at 40°C, and the in vitro release of curcumin was sustained (10% or less over 15 days. Fluorescence-activated cell sorting (FACS analysis using a human colon cancer cell line (HCT116 exhibited 99.1% fluorescence gating for 5 µM curcumin-loaded LCN dispersion compared to 1.36% for the same concentration of the drug in dimethyl sulfoxide (DMSO, indicating markedly enhanced cellular uptake. Consistent with the enhanced cellular uptake of curcumin-loaded LCNs, anticancer activity and cell cycle studies demonstrated apoptosis induction when the cells were treated with the LCN dispersion; however, there was neither noticeable cell death nor significant changes in the cell cycle for the same concentration of the drug in DMSO. In conclusion, entrapping curcumin into MO-based LCNs may provide, in the future, a strategy for overcoming the hurdles associated with both the stability and cellular uptake issues of the drug in the treatment of various cancers. Keywords: liquid

  5. Measuring negative symptoms in patients with schizophrenia: reliability and validity of the Korean version of the Motivation and Pleasure Scale-Self-Report

    Directory of Open Access Journals (Sweden)

    Kim JS

    2016-05-01

    Full Text Available Ji-Sun Kim,1 Seon-Kyeong Jang,1 Seon-Cheol Park,2 Jung-Seo Yi,3 Joong-Kyu Park,4 Jung Suk Lee,5 Kee-Hong Choi,6 Seung-Hwan Lee1,7 1Clinical Emotion and Cognition Research Laboratory, Goyang, 2Department of Psychiatry, Inje University Haeundae Paik Hospital, Busan, 3Department of Psychiatry, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 4Department of Rehabilitation Psychology, Daegu University, Daegu, 5Department of Psychiatry, National Health Insurance Service Ilsan Hospital, Goyang, 6Department of Psychology, Korea University, Seoul, 7Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea Background: The Clinical Assessment Interview for Negative Symptoms (CAINS is one of the validated interview measures of negative symptoms in psychotic disorders. The Motivation and Pleasure Scale-Self-Report (MPSR is a self-report measure that assesses the motivation and pleasure domains of negative symptoms based on the CAINS. This study evaluated the reliability and validity of a Korean version of the MPSR.Methods: A total of 139 patients with schizophrenia completed the MPSR, CAINS, Scale for the Assessment of Negative Symptoms (SANS, Brief Psychiatric Rating Scales, Calgary Depression Scale for Schizophrenia, and other measures of trait and cognitive function.Results: The 15-item MPSR showed good internal consistency. In addition, it also had a good convergent validity with the Motivation and Pleasure subscale of the CAINS and the anhedonia/avolition subscale of the SANS. The scale was not associated with psychotic symptoms, agitation/mania, and depression/anxiety, and it showed good discriminant validity. MPSR scores were significantly correlated with Behavioral Activation System total score for trait measure.Conclusion: The Korean version of the MPSR is a notable self-report method for examining the severity of negative symptoms in schizophrenia. Keywords: Korean

  6. Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension

    Directory of Open Access Journals (Sweden)

    Ahn KT

    2016-04-01

    Full Text Available Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea Objectives: Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. Methods: Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg were enrolled. Central blood pressure and radial augmentation index (AIx corrected for a heart rate of 75 bpm (radial AIx 75 were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension. Results: A total of 203 patients were enrolled, of whom men numbered 101 (49.7%. The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005, a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R2=0.428, β=6.237, 95% confidence interval [CI] for women 1.480–10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively. Conclusion: In patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75. Keywords: hypertension, augmentation index, height, sex

  7. Hyaluronan-conjugated liposomes encapsulating gemcitabine for breast cancer stem cells

    Directory of Open Access Journals (Sweden)

    Han NK

    2016-04-01

    Full Text Available Na-Kyung Han,1,* Dae Hwan Shin,1,* Jung Seok Kim,1 Kwon Yeon Weon,2 Chang-Young Jang,1 Jin-Seok Kim1 1Research Center for Cell Fate Control (RCCFC and College of Pharmacy, Sookmyung Women’s University, Seoul, 2College of Pharmacy, Catholic University of Daegu, Gyeongbuk, Korea *These authors contributed equally to this work Abstract: Investigation of potential therapeutics for targeting breast cancer stem cells (BCSCs is important because these cells are regarded as culprit of breast cancer relapse. Accomplishing this kind of strategy requires a specific drug-delivery system using the distinct features of liposomes. Studies on targeted liposomal delivery systems have indicated the conjugation of hyaluronan (HA, a primary ligand for CD44 surface markers, as an appropriate method for targeting BCSCs. For this study, enriched BCSCs were obtained by culturing MCF-7 breast cancer cells in nonadherent conditions. The enriched BCSCs were challenged with HA-conjugated liposomes encapsulating gemcitabine (2, 2-difluoro-2-deoxycytidine, GEM. In vitro study showed that the HA-conjugated liposomes significantly enhanced the cytotoxicity, anti-migration, and anti-colony formation abilities of GEM through targeting of CD44 expressed on BCSCs. In pharmacokinetic study, area under the drug concentration vs time curve (AUC of the immunoliposomal GEM was 3.5 times higher than that of free GEM, indicating that the HA-conjugated liposomes enhanced the stability of GEM in the bloodstream and therefore prolonged its half-life time. The antitumor effect of the immunoliposomal GEM was 3.3 times higher than that of free GEM in a xenograft mouse model, probably reflecting the unique targeting of the CD44 receptor by HA and the increased cytotoxicity and stability through the liposomal formulation. Furthermore, marginal change in body weight demonstrated that the use of liposomes considerably reduced the systemic toxicity of GEM on normal healthy cells. Taken together

  8. Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

    Directory of Open Access Journals (Sweden)

    Ha ES

    2015-08-01

    Full Text Available Eun-Sol Ha,1 Jeong-Soo Kim,2 In-hwan Baek,3 Jin-Wook Yoo,1 Yunjin Jung,1 Hyung Ryong Moon,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2Dong-A ST Co Ltd, Yongin, 3College of Pharmacy, Kyungsung University, Busan, South Korea Abstract: In the present study, solid dispersion nanoparticles with a hydrophilic polymer and surfactant were developed using the supercritical antisolvent (SAS process to improve the dissolution and oral absorption of megestrol acetate. The physicochemical properties of the megestrol acetate solid dispersion nanoparticles were characterized using scanning electron microscopy, differential scanning calorimetry, powder X-ray diffraction, and a particle-size analyzer. The dissolution and oral bioavailability of the nanoparticles were also evaluated in rats. The mean particle size of all solid dispersion nanoparticles that were prepared was <500 nm. Powder X-ray diffraction and differential scanning calorimetry measurements showed that megestrol acetate was present in an amorphous or molecular dispersion state within the solid dispersion nanoparticles. Hydroxypropylmethyl cellulose (HPMC solid dispersion nanoparticles significantly increased the maximum dissolution when compared with polyvinylpyrrolidone K30 solid dispersion nanoparticles. The extent and rate of dissolution of megestrol acetate increased after the addition of a surfactant into the HPMC solid dispersion nanoparticles. The most effective surfactant was Ryoto sugar ester L1695, followed by d-a-tocopheryl polyethylene glycol 1000 succinate. In this study, the solid dispersion nanoparticles with a drug:HPMC:Ryoto sugar ester L1695 ratio of 1:2:1 showed >95% rapid dissolution within 30 minutes, in addition to good oral bioavailability, with approximately 4.0- and 5.5-fold higher area under the curve (0–24 hours and maximum concentration, respectively, than raw megestrol acetate powder. These results suggest that the preparation of megestrol

  9. Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

    Directory of Open Access Journals (Sweden)

    Kim YH

    2015-06-01

    Full Text Available Yo Han Kim,1 Hee Youn Choi,1 Yook-Hwan Noh,1 Shi Hyang Lee,1 Hyeong-Seok Lim,1 Chin Kim,2 Kyun-Seop Bae11Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, 2Chong Kun Dang Clinical Research and Clinical Epidemiology and Medical Information, CKD Pharmaceuticals, Seoul, Republic of KoreaBackground: Carvedilol is a third-generation β-blocker indicated for congestive heart failure and high blood pressure. The aim of this study was to investigate the dose proportionality of the carvedilol sustained-release (SR formulation in healthy male subjects.Methods: An open-label, single dose-ascending, 10-sequence, 3-period balanced incomplete block study was performed using healthy male subjects. In varying sequences, each subject received three of five carvedilol SR formulations (8, 16, 32, 64, or 128 mg once. The treatment periods were separated by a washout period of 7 days. Serial blood samples were collected up to 48 h after dosing. The plasma concentrations of carvedilol were determined by using validated liquid chromatography–tandem mass spectrometry. Pharmacokinetic parameters including the area under the plasma concentration–time curve (AUC from time 0 to the last measurable time (AUClast, AUC extrapolated to infinity (AUCinf, and the measured peak plasma concentration (Cmax were obtained by noncompartmental analysis. Dose proportionality was evaluated if the ln–ln plots of AUClast, AUCinf, and Cmax versus dose were linear and the 90% confidence intervals (CIs of the slopes were within 0.9195 and 1.0805. Tolerability was assessed by vital signs, electrocardiogram, clinical laboratory tests, and monitoring of adverse events (AEs throughout the study.Results: A total of 31 subjects were enrolled, and 30 completed the study. The assessment of dose proportionality meets the statistical criteria; the point estimates of slope were 1.0104 (90% CI: 0.9849–1.0359 for AUClast, 1

  10. Vorinostat-eluting poly(DL-lactide-co-glycolide nanofiber-coated stent for inhibition of cholangiocarcinoma cells

    Directory of Open Access Journals (Sweden)

    Kwak TW

    2017-10-01

    Full Text Available Tae Won Kwak,1,* Hye Lim Lee,2,* Yeon Hui Song,2 Chan Kim,3 Jungsoo Kim,2 Sol-Ji Seo,2 Young-Il Jeong,2 Dae Hwan Kang2,4 1Medical Convergence Textile Center, Gyeongbuk, Republic of Korea; 2Biomedical Research Institute, Pusan National University Hospital, Pusan, Republic of Korea; 3Amogreentech Co. Ltd. Gyeonggi-do, Republic of Korea; 4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongnam, Republic of Korea *These authors contributed equally to this work Purpose: The aim of this study was to fabricate a vorinostat (Zolinza™-eluting nanofiber membrane-coated gastrointestinal (GI stent and to study its antitumor activity against cholangiocarcinoma (CCA cells in vitro and in vivo. Methods: Vorinostat and poly(DL-lactide-co-glycolide dissolved in an organic solvent was sprayed onto a GI stent to make a nanofiber-coated stent using an electro-spinning machine. Intact vorinostat and vorinostat released from nanofibers was used to assess anticancer activity in vitro against various CCA cells. The antitumor activity of the vorinostat-eluting nanofiber membrane-coated stent was evaluated using HuCC-T1 bearing mice. Results: A vorinostat-incorporated polymer nanofiber membrane was formed on the surface of the GI stent. Vorinostat was continuously released from the nanofiber membrane over 10 days, and its release rate was higher in cell culture media than in phosphate-buffered saline. Released vorinostat showed similar anticancer activity against various CCA cells in vitro compared to that of vorinostat. Like vorinostat, vorinostat released from nanofibers induced acetylation of histone H4 and inhibited histone deacetylases 1·3·4/5/7 expression in vitro and in vivo. Furthermore, vorinostat nanofibers showed a higher tumor growth inhibition rate in HuCC-T1 bearing mice than vorinostat injections. Conclusion: Vorinostat-eluting nanofiber membranes showed significant antitumor

  11. Novel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate

    Directory of Open Access Journals (Sweden)

    Yousaf AM

    2016-01-01

    Full Text Available Abid Mehmood Yousaf,1,2 Omer Mustapha,1 Dong Wuk Kim,1 Dong Shik Kim,1 Kyeong Soo Kim,1 Sung Giu Jin,1 Chul Soon Yong,3 Yu Seok Youn,4 Yu-Kyoung Oh,5 Jong Oh Kim,3 Han-Gon Choi1 1College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi, South Korea; 2Faculty of Pharmacy, University of Central Punjab, Johar, Lahore, Pakistan; 3College of Pharmacy, Yeungnam University, Gyongsan, North Gyeongsang, 4School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi, 5College of Pharmacy, Seoul National University, Seoul, South Korea Purpose: The purpose of the present research was to develop a novel electrosprayed nanospherule providing the most optimized aqueous solubility and oral bioavailability for poorly water-soluble fenofibrate.Methods: Numerous fenofibrate-loaded electrosprayed nanospherules were prepared with polyvinylpyrrolidone (PVP and Labrafil® M 2125 as carriers using the electrospray technique, and the effect of the carriers on drug solubility and solvation was assessed. The solid state characterization of an optimized formulation was conducted by scanning electron microscopy, powder X-ray diffraction, differential scanning calorimetry, and Fourier transform infrared spectroscopic analyses. Oral bioavailability in rats was also evaluated for the formulation of an optimized nanospherule in comparison with free drug and a conventional fenofibrate-loaded solid dispersion.Results: All of the electrosprayed nanospherule formulations had remarkably enhanced aqueous solubility and dissolution compared with free drug. Moreover, Labrafil M 2125, a surfactant, had a positive influence on the solubility and dissolution of the drug in the electrosprayed nanospherule. Increases were observed as the PVP/drug ratio increased to 4:1, but higher ratios gave no significant increases. In particular, an electrosprayed nanospherule composed of fenofibrate, PVP, and Labrafil M 2125 at the weight ratio of 1

  12. Three-dimensional culture and interaction of cancer cells and dendritic cells in an electrospun nano-submicron hybrid fibrous scaffold

    Directory of Open Access Journals (Sweden)

    Kim TE

    2016-03-01

    Full Text Available Tae-Eon Kim,1–3,* Chang Gun Kim,1–3,* Jin Soo Kim,4 Songwan Jin,4 Sik Yoon,5 Hae-Rahn Bae,6 Jeong-Hwa Kim,7,8 Young Hun Jeong,7,8 Jong-Young Kwak1–3 1Department of Pharmacology, School of Medicine, 2Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea; 3Immune Network Pioneer Research Center, Ajou University Medical Center, Suwon, South Korea; 4Department of Mechanical Engineering, Korea Polytechnic University, Gyeonggi, South Korea; 5Department of Anatomy, School of Medicine, Pusan National University, Yangsan, South Korea; 6Department of Physiology, College of Medicine, Dong-A University, Busan, South Korea; 7School of Mechanical Engineering, 8Department of Mechanical Engineering, Graduate School, Kyungpook National University, Daegu, South Korea *These authors contributed equally to this work Abstract: An artificial three-dimensional (3D culture system that mimics the tumor microenvironment in vitro is an essential tool for investigating the cross-talk between immune and cancer cells in tumors. In this study, we developed a 3D culture system using an electrospun poly(ε-caprolactone (PCL nanofibrous scaffold (NFS. A hybrid NFS containing an uninterrupted network of nano- and submicron-scale fibers (400 nm to 2 µm was generated by deposition onto a stainless steel mesh instead of an aluminum plate. The hybrid NFS contained multiplanar pores in a 3D structure. Surface-seeded mouse CT26 colon cancer cells and bone marrow-derived dendritic cells (BM-DCs were able to infiltrate the hybrid NFS within several hours. BM-DCs cultured on PCL nanofibers showed a baseline inactive form, and lipopolysaccharide (LPS-activated BM-DCs showed increased expression of CD86 and major histocompatibility complex Class II. Actin and phosphorylated FAK were enriched where unstimulated and LPS-stimulated BM-DCs contacted the fibers in the 3D hybrid NFS. When BM-DCs were cocultured with mitoxantrone-treated CT26 cells in

  13. Diminished autonomic neurocardiac function in patients with generalized anxiety disorder

    Directory of Open Access Journals (Sweden)

    Kim K

    2016-12-01

    Full Text Available Kyungwook Kim,1 Seul Lee,2 Jong-Hoon Kim1–3 1Gachon University School of Medicine, 2Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine, Gachon University, 3Neuroscience Research Institute, Gachon University, Incheon, Republic of Korea Background: Generalized anxiety disorder (GAD is a chronic and highly prevalent disorder that is characterized by a number of autonomic nervous system symptoms. The purpose of this study was to investigate the linear and nonlinear complexity measures of heart rate variability (HRV, measuring autonomic regulation, and to evaluate the relationship between HRV parameters and the severity of anxiety, in medication-free patients with GAD. Methods: Assessments of linear and nonlinear complexity measures of HRV were performed in 42 medication-free patients with GAD and 50 healthy control subjects. In addition, the severity of anxiety symptoms was assessed using the State-Trait Anxiety Inventory and Beck Anxiety Inventory. The values of the HRV measures of the groups were compared, and the correlations between the HRV measures and the severity of anxiety symptoms were assessed. Results: The GAD group showed significantly lower standard deviation of RR intervals and the square root of the mean squared differences of successive normal sinus intervals values compared to the control group (P<0.01. The approximate entropy value, which is a nonlinear complexity indicator, was also significantly lower in the patient group than in the control group (P<0.01. In correlation analysis, there were no significant correlations between HRV parameters and the severity of anxiety symptoms. Conclusion: The present study indicates that GAD is significantly associated with reduced HRV, suggesting that autonomic neurocardiac integrity is substantially impaired in patients with GAD. Future prospective studies are required to investigate the effects of pharmacological or non-pharmacological treatment on

  14. [The early medical textbooks in Korea: medical textbooks published at Je Joong Won-Severance Hospital Medical School].

    Science.gov (United States)

    Park, H W

    1998-01-01

    Kwang Hye Won(Je Joong Won), the first western hospital in Korea, was founded in 1885. The first western Medical School in Korea was open in 1886 under the hospital management. Dr. O. R. Avison, who came to Korea in 1893, resumed the medical education there, which was interrupted for some time before his arrival in Korea. He inaugurated translating and publishing medical textbooks with the help of Kim Pil Soon who later became one of the first seven graduates in Severance Hospital Medical School. The first western medical textbook translated into Korean was Henry Gray's Anatomy. However, these twice-translated manuscripts were never to be published on account of being lost and burnt down. The existing early anatomy textbooks, the editions of 1906 and 1909, are not the translation of Gray's Anatomy, but that of Japanese anatomy textbook of Gonda. The remaining oldest medical textbook in Korean is Inorganic Materia Medica published in 1905. This book is unique among its kind that O. R. Avison is the only translator of the book and it contains the prefaces of O. R. Avison and Kim Pil Soon. The publication of medical textbook was animated by the participation of other medical students, such as Hong Suk Hoo and Hong Jong Eun. The list of medical textbooks published includes almost all the field of medicine. The medical textbooks in actual existence are as follows: Inorganic Materia Medica (1905), Inorganic Chemistry (1906), Anatomy I (1906), Physiology (1906), Diagnostics I (1906), Diagnostics II (1907), Obstetrics (1908), Organic Chemistry (1909), Anatomy (1909), and Surgery (1910).

  15. Analysis of North Korea's Nuclear Tests under Prospect Theory

    International Nuclear Information System (INIS)

    Lee, Han Myung; Ryu, Jae Soo; Lee, Kwang Seok; Lee, Dong Hoon; Jun, Eunju; Kim, Mi Jin

    2013-01-01

    North Korea has chosen nuclear weapons as the means to protect its sovereignty. Despite international society's endeavors and sanctions to encourage North Korea to abandon its nuclear ambition, North Korea has repeatedly conducted nuclear testing. In this paper, the reason for North Korea's addiction to a nuclear arsenal is addressed within the framework of cognitive psychology. The prospect theory addresses an epistemological approach usually overlooked in rational choice theories. It provides useful implications why North Korea, being under a crisis situation has thrown out a stable choice but taken on a risky one such as nuclear testing. Under the viewpoint of prospect theory, nuclear tests by North Korea can be understood as follows: The first nuclear test in 2006 is seen as a trial to escape from loss areas such as financial sanctions and regime threats; the second test in 2009 was interpreted as a consequence of the strategy to recover losses by making a direct confrontation against the United States; and the third test in 2013 was understood as an attempt to strengthen internal solidarity after Kim Jong-eun inherited the dynasty, as well as to enhance bargaining power against the United States. Thus, it can be summarized that Pyongyang repeated its nuclear tests to escape from a negative domain and to settle into a positive one. In addition, in the future, North Korea may not be willing to readily give up its nuclear capabilities to ensure the survival of its own regime

  16. Analysis of North Korea's Nuclear Tests under Prospect Theory

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Han Myung; Ryu, Jae Soo; Lee, Kwang Seok; Lee, Dong Hoon; Jun, Eunju; Kim, Mi Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    North Korea has chosen nuclear weapons as the means to protect its sovereignty. Despite international society's endeavors and sanctions to encourage North Korea to abandon its nuclear ambition, North Korea has repeatedly conducted nuclear testing. In this paper, the reason for North Korea's addiction to a nuclear arsenal is addressed within the framework of cognitive psychology. The prospect theory addresses an epistemological approach usually overlooked in rational choice theories. It provides useful implications why North Korea, being under a crisis situation has thrown out a stable choice but taken on a risky one such as nuclear testing. Under the viewpoint of prospect theory, nuclear tests by North Korea can be understood as follows: The first nuclear test in 2006 is seen as a trial to escape from loss areas such as financial sanctions and regime threats; the second test in 2009 was interpreted as a consequence of the strategy to recover losses by making a direct confrontation against the United States; and the third test in 2013 was understood as an attempt to strengthen internal solidarity after Kim Jong-eun inherited the dynasty, as well as to enhance bargaining power against the United States. Thus, it can be summarized that Pyongyang repeated its nuclear tests to escape from a negative domain and to settle into a positive one. In addition, in the future, North Korea may not be willing to readily give up its nuclear capabilities to ensure the survival of its own regime.

  17. Improvement in the amine glass platform by bubbling method for a DNA microarray

    Directory of Open Access Journals (Sweden)

    Jee SH

    2015-10-01

    Full Text Available Seung Hyun Jee,1 Jong Won Kim,2 Ji Hyeong Lee,2 Young Soo Yoon11Department of Chemical and Biological Engineering, Gachon University, Seongnam, Gyeonggi, Republic of Korea; 2Genomics Clinical Research Institute, LabGenomics Co., Ltd., Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of KoreaAbstract: A glass platform with high sensitivity for sexually transmitted diseases microarray is described here. An amino-silane-based self-assembled monolayer was coated on the surface of a glass platform using a novel bubbling method. The optimized surface of the glass platform had highly uniform surface modifications using this method, as well as improved hybridization properties with capture probes in the DNA microarray. On the basis of these results, the improved glass platform serves as a highly reliable and optimal material for the DNA microarray. Moreover, in this study, we demonstrated that our glass platform, manufactured by utilizing the bubbling method, had higher uniformity, shorter processing time, lower background signal, and higher spot signal than the platforms manufactured by the general dipping method. The DNA microarray manufactured with a glass platform prepared using bubbling method can be used as a clinical diagnostic tool. Keywords: DNA microarray, glass platform, bubbling method, self-assambled monolayer

  18. The Astronomical Instrument, So-Gahui Invented During King Sejong Period

    Science.gov (United States)

    Lee, Yong-Sam Lee; Kim, Sang-Hyuk

    2002-09-01

    So-ganui, namely small simplified armillary sphere, was invented as an astronomical instrument by Lee Cheon, Jeong Cho, Jung In-Ji under 16 years' rule of King Sejong. We collect records and observed data on So-ganui. It is designed to measure position of celestial sphere and to determine time. It also can be transformed equatorial to horizontal, and horizontal to equatorial coordinate. It can measure the right ascension, declination, altitude and azimuth. It is composed of Sayu-hwan (Four displacements), Jeokdo-hwan (Equatorial dial), Baekgak-hwan (Ring with one hundred-interval quarters), Gyuhyeong (Sighting aliadade), Yongju (Dragon-pillar) and Bu (Stand). So-ganui was used conveniently portable surveying as well as astronomical instrument and possible to determine time during day and night.

  19. North Korea's satellite launch: provocation and ballistic progress

    International Nuclear Information System (INIS)

    Sitt, Bernard

    2013-12-01

    North Korea's putting into orbit of a small meteorological satellite using an Unha-3 launcher on the 13 December 2013, a year on from Kim Jong-il's passing, smacks of provocation. The launch of an SLV that is closely related to the Taepodong-2 and that has numerous characteristics in common with a long-range ballistic missile contravened Security Council Resolutions 1695 (2006), 1718 (2006), and 1874 (2009), adopted in response to nuclear and ballistic tests carried out by Pyongyang. These resolutions implemented a progressively more strenuous regime of sanctions, which cannot fail to have marked the North Korean dictatorship, at least in economic and financial terms. The provisional successes and failures of the Six-party talks, mediated by China, which have been at a dead-end since 2009 bear witness to the unpredictability of the North's reactions. Pyongyang's double-agenda is, nonetheless, relatively easily to discern. Firstly, with this successful launch, North Korea has redeemed the failure of the first Unha-3 launch on the 13 April 2012, at the same time as Kim Jong-un took power and the country was celebrating the centenary of the birth of its founder, Kim Il-sung. This success evidently helps to bolster both the young leader's prestige on the domestic front and his sway over the army. Simultaneously, and beyond any symbolic value, North Korea's development of long-range ballistic capabilities constitutes veritable progress, on the back of a series of failures since 2006. Naturally, the reliability of the Unha-3 launcher (or of an improved Taepodong-2) is by no means guaranteed. Moreover, its payload is limited, since it can presently only launch small satellites, and thus well below the capacity needed to carry a nuclear weapon. If this is indeed North Korea's objective in years to come, it will need to make considerable technological progress, including the development of sufficiently small nuclear devices, which would necessitate further nuclear tests. In

  20. North Korea's satellite launch: provocation and ballistic progress; Le lancement d'un satellite par la Coree du Nord: entre provocation et progres des capacites balistiques

    Energy Technology Data Exchange (ETDEWEB)

    Sitt, Bernard

    2013-12-15

    North Korea's putting into orbit of a small meteorological satellite using an Unha-3 launcher on the 13 December 2013, a year on from Kim Jong-il's passing, smacks of provocation. The launch of an SLV that is closely related to the Taepodong-2 and that has numerous characteristics in common with a long-range ballistic missile contravened Security Council Resolutions 1695 (2006), 1718 (2006), and 1874 (2009), adopted in response to nuclear and ballistic tests carried out by Pyongyang. These resolutions implemented a progressively more strenuous regime of sanctions, which cannot fail to have marked the North Korean dictatorship, at least in economic and financial terms. The provisional successes and failures of the Six-party talks, mediated by China, which have been at a dead-end since 2009 bear witness to the unpredictability of the North's reactions. Pyongyang's double-agenda is, nonetheless, relatively easily to discern. Firstly, with this successful launch, North Korea has redeemed the failure of the first Unha-3 launch on the 13 April 2012, at the same time as Kim Jong-un took power and the country was celebrating the centenary of the birth of its founder, Kim Il-sung. This success evidently helps to bolster both the young leader's prestige on the domestic front and his sway over the army. Simultaneously, and beyond any symbolic value, North Korea's development of long-range ballistic capabilities constitutes veritable progress, on the back of a series of failures since 2006. Naturally, the reliability of the Unha-3 launcher (or of an improved Taepodong-2) is by no means guaranteed. Moreover, its payload is limited, since it can presently only launch small satellites, and thus well below the capacity needed to carry a nuclear weapon. If this is indeed North Korea's objective in years to come, it will need to make considerable technological progress, including the development of sufficiently small nuclear devices, which would necessitate further nuclear tests. In

  1. Comparison of tadalafil pharmacokinetics after administration of a new orodispersible film versus a film-coated tablet

    Directory of Open Access Journals (Sweden)

    Park SI

    2018-04-01

    Full Text Available Sang-In Park,1,* Su-Hak Heo,2,3,* Gihwan Kim,2 Seokhoon Chang,2 Keon-Hyoung Song,3 Min-Gul Kim,4 Eun-Heui Jin,5 JaeWoo Kim,5 SeungHwan Lee,1 Jang Hee Hong5,6 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; 2R&D Center, C.L. Pharm Co., Ltd, Seoul, Republic of Korea; 3Department of Pharmaceutical Engineering, College of Medical Science, Soonchunhyang University, Asan, Republic of Korea; 4Department of Pharmacology, School of Medicine, Chonbuk National University, Jeonju, Republic of Korea; 5Clinical Trials Center, Chungnam National University Hospital, Daejeon, Republic of Korea; 6Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, Republic of Korea *These authors contributed equally to this work Background: An orodispersible film (ODF of tadalafil may provide increased convenience for erectile dysfunction (ED patients as compared to conventional tablet formulations. In this study, we aimed to compare the pharmacokinetic, safety, and tolerability profiles of a newly developed ODF formulation of tadalafil to those of a film-coated tablet (FCT of tadalafil.Materials and methods: This study was conducted in healthy male subjects using an open-label, randomized sequence, two-period, two-formulation, single-dose, crossover design. The subjects were randomly assigned to one of two sequences of the two formulations: both the test drug (ODF and the reference drug (FCT contained 20 mg of tadalafil. Blood samples were collected up to 72 h after administration. Plasma concentrations of tadalafil were analyzed using liquid chromatography–tandem mass spectrometry. Geometric mean ratios (GMRs of the ODF to FCT formulations and their 90% CIs for the pharmacokinetic parameters were estimated. Safety and tolerability were assessed throughout the study.Results: Forty healthy male subjects were enrolled, and 36 of these completed the

  2. Optical imaging of absorption and distribution of RITC-SiO2 nanoparticles after oral administration

    Directory of Open Access Journals (Sweden)

    Lee CM

    2014-12-01

    Full Text Available Chang-Moon Lee,1 Tai Kyoung Lee,2–5 Dae-Ik Kim,1,6 Yu-Ri Kim,7 Meyoung-Kon Kim,7 Hwan-Jeong Jeong,2–5 Myung-Hee Sohn,2–5 Seok Tae Lim2–5 1Department of Biomedical Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 2Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 3Cyclotron Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 4Biomedical Research Institute, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 5Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 6School of Electrical, Electronic Communication, and Computer Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 7Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seounbuk-Gu, Seoul, Republic of Korea Purpose: In this study, we investigated the absorption and distribution of rhodamine B isothiocyanate (RITC-incorporated silica oxide nanoparticles(SiNPs (RITC-SiNPs after oral exposure, by conducting optical imaging, with a focus on tracking the movement of RITC-SiNPs of different particle size and surface charge. Methods: RITC-SiNPs (20 or 100 nm; positively or negatively charged were used to avoid the dissociation of a fluorescent dye from nanoparticles via spontaneous or enzyme-catalyzed reactions in vivo. The changes in the nanoparticle sizes and shapes were investigated in an HCl solution for 6 hours. RITC-SiNPs were orally administered to healthy nude mice at a dose of 100 mg/kg. Optical imaging studies were performed at 2, 4, and 6 hours after oral administration. The mice were sacrificed at 2, 4, 6, and 10 hours post-administration, and ex vivo imaging studies were performed

  3. Iron oxide-based nanomagnets in nanomedicine: fabrication and applications

    Directory of Open Access Journals (Sweden)

    Meng Meng Lin

    2010-02-01

    Full Text Available Iron oxide-based nanomagnets have attracted a great deal of attention in nanomedicine over the past decade. Down to the nanoscale, superparamagnetic iron oxide nanoparticles can only be magnetized in the presence of an external magnetic field, which makes them capable of forming stable colloids in a physio-biological medium. Their superparamagnetic property, together with other intrinsic properties, such as low cytotoxicity, colloidal stability, and bioactive molecule conjugation capability, makes such nanomagnets ideal in both in-vitro and in-vivo biomedical applications. In this review, a chemical, physical, and biological synthetic approach to prepare iron oxide-based nanomagnets with different physicochemical properties was illustrated and compared. The growing interest in iron oxide-based nanomagnets with multifunctionalities was explored in cancer diagnostics and treatment, focusing on their combined roles in a magnetic resonance contrast agent, hyperthermia, and magnetic force assisted drug delivery. Iron oxides as magnetic carriers in gene therapy were reviewed with a focus on the sophisticated design and construction of magnetic vectors. Finally, the iron oxide-based nanomagnet also represents a very promising tool in particle/cell interfacing in controlling cellular functionalities, such as adhesion, proliferation, differentiation, and cell patterning, in stem cell therapy and tissue engineering applications. Meng Meng Lin received a BSc in biotechnology at the University of Hong Kong, China in 2004 and an MSc in biomedical nanotechnology at Newcastle University, UK, in 2005. She is currently working toward her PhD at the Institute of Science and Technology in Medicine, Keele University, UK. She was a visiting student at the Royal Institute of Technology, Sweden, in 2006. Her research interests include nanoparticles preparation, cell/nanomaterials interface, and cancer-oriented drug delivery. Hyung-Hwan Kim received an MSc degree in

  4. Tissue distribution and excretion kinetics of orally administered silica nanoparticles in rats

    Directory of Open Access Journals (Sweden)

    Lee JA

    2014-12-01

    Full Text Available Jeong-A Lee,1 Mi-Kyung Kim,1 Hee-Jeong Paek,1 Yu-Ri Kim,2 Meyoung-Kon Kim,2 Jong-Kwon Lee,3 Jayoung Jeong,3 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, Republic of Korea; 3Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungchungbuk–do, Republic of Korea Purpose: The effects of particle size on the tissue distribution and excretion kinetics of silica nanoparticles and their biological fates were investigated following a single oral administration to male and female rats. Methods: Silica nanoparticles of two different sizes (20 nm and 100 nm were orally administered to male and female rats, respectively. Tissue distribution kinetics, excretion profiles, and fates in tissues were analyzed using elemental analysis and transmission electron microscopy. Results: The differently sized silica nanoparticles mainly distributed to kidneys and liver for 3 days post-administration and, to some extent, to lungs and spleen for 2 days post-administration, regardless of particle size or sex. Transmission electron microscopy and energy dispersive spectroscopy studies in tissues demonstrated almost intact particles in liver, but partially decomposed particles with an irregular morphology were found in kidneys, especially in rats that had been administered 20 nm nanoparticles. Size-dependent excretion kinetics were apparent and the smaller 20 nm particles were found to be more rapidly eliminated than the larger 100 nm particles. Elimination profiles showed 7%–8% of silica nanoparticles were excreted via urine, but most nanoparticles were excreted via feces, regardless of particle size or sex. Conclusion: The kidneys, liver, lungs, and spleen were found to be the target organs of orally-administered silica nanoparticles in rats, and this organ

  5. Short- and long-term outcomes of laparoscopic surgery vs open surgery for transverse colon cancer: a retrospective multicenter study

    Directory of Open Access Journals (Sweden)

    Kim JW

    2016-04-01

    Full Text Available Jong Wan Kim,1 Jeong Yeon Kim,1 Byung Mo Kang,2 Bong Hwa Lee,3 Byung Chun Kim,4 Jun Ho Park5 1Department of Surgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong Si, 2Department of Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon Si, 3Department of Surgery, Hallym Sacred Heart Hospital, College of Medicine, Hallym University, Anyang Si, 4Department of Surgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, 5Department of Surgery, Kangdong Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea Purpose: The purpose of the present study was to compare the perioperative and oncologic outcomes between laparoscopic surgery and open surgery for transverse colon cancer.Patients and methods: We conducted a retrospective review of patients who underwent surgery for transverse colon cancer at six Hallym University-affiliated hospitals between January 2005 and June 2015. The perioperative outcomes and oncologic outcomes were compared between laparoscopic and open surgery.Results: Of 226 patients with transverse colon cancer, 103 underwent laparoscopic surgery and 123 underwent open surgery. There were no differences in the patient characteristics between the two groups. Regarding perioperative outcomes, the operation time was significantly longer in the laparoscopic group than in the open group (267.3 vs 172.7 minutes, P<0.001, but the time to soft food intake (6.0 vs 6.6 days, P=0.036 and the postoperative hospital stay (13.7 vs 15.7 days, P=0.018 were shorter in the laparoscopic group. The number of harvested lymph nodes was lower in the laparoscopic group than in the open group (20.3 vs 24.3, P<0.001. The 5-year overall survival (90.8% vs 88.6%, P=0.540 and disease-free survival (86.1% vs 78.9%, P=0.201 rates were similar in both groups.Conclusion: The present study showed that laparoscopic surgery is associated

  6. PLGA nanofiber membranes loaded with epigallocatechin-3-O-gallate are beneficial to prevention of postsurgical adhesions

    Directory of Open Access Journals (Sweden)

    Shin YC

    2014-08-01

    Full Text Available Yong Cheol Shin,1,* Won Jun Yang,1,* Jong Ho Lee,1 Jin-Woo Oh,2 Tai Wan Kim,3 Jong-Chul Park,4 Suong-Hyu Hyon,5 Dong-Wook Han1 1Department of Cogno-Mechatronics Engineering, Pusan National University, Busan, Republic of Korea; 2Department of Nanomaterials Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan, Republic of Korea; 3Department of Design, College of Arts, Pusan National University, Busan, Republic of Korea; 4Department of Medical Engineering, Yonsei University College of Medicine, Seoul, Republic of Korea; 5Center for Fiber and Textile Science, Kyoto Institute of Technology, Kyoto, Japan *These authors contributed equally to this work Abstract: This study concentrates on the development of biodegradable nanofiber membranes with controlled drug release to ensure reduced tissue adhesion and accelerated healing. Nanofibers of poly(lactic-co-glycolic acid (PLGA loaded with epigallocatechin-3-O-gallate (EGCG, the most bioactive polyphenolic compound in green tea, were electrospun. The physicochemical and biomechanical properties of EGCG-releasing PLGA (E-PLGA nanofiber membranes were characterized by atomic force microscopy, EGCG release and degradation profiles, and tensile testing. In vitro antioxidant activity and hemocompatibility were evaluated by measuring scavenged reactive oxygen species levels and activated partial thromboplastin time, respectively. In vivo antiadhesion efficacy was examined on the rat peritonea with a surgical incision. The average fiber diameter of E-PLGA membranes was approximately 300–500 nm, which was almost similar to that of pure PLGA equivalents. E-PLGA membranes showed sustained EGCG release mediated by controlled diffusion and PLGA degradation over 28 days. EGCG did not adversely affect the tensile strength of PLGA membranes, whereas it significantly decreased the elastic modulus and increased the strain at break. E-PLGA membranes were significantly effective in

  7. Analysis of SiO2 nanoparticles binding proteins in rat blood and brain homogenate

    Directory of Open Access Journals (Sweden)

    Shim KH

    2014-12-01

    Full Text Available Kyu Hwan Shim,1 John Hulme,1 Eun Ho Maeng,2 Meyoung-Kon Kim,3 Seong Soo A An1 1Department of Bionano Technology, Gachon Medical Research Institute, Gachon University, Sungnam-si, 2Department of Analysis, KTR, Kimpo, Gyeonggi-do, 3Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea Abstract: A multitude of nanoparticles, such as titanium oxide (TiO2, zinc oxide, aluminum oxide, gold oxide, silver oxide, iron oxide, and silica oxide, are found in many chemical, cosmetic, pharmaceutical, and electronic products. Recently, SiO2 nanoparticles were shown to have an inert toxicity profile and no association with an irreversible toxicological change in animal models. Hence, exposure to SiO2 nanoparticles is on the increase. SiO2 nanoparticles are routinely used in numerous materials, from strengthening filler for concrete and other construction composites, to nontoxic platforms for biomedical application, such as drug delivery and theragnostics. On the other hand, recent in vitro experiments indicated that SiO2 nanoparticles were cytotoxic. Therefore, we investigated these nanoparticles to identify potentially toxic pathways by analyzing the adsorbed protein corona on the surface of SiO2 nanoparticles in the blood and brain of the rat. Four types of SiO2 nanoparticles were chosen for investigation, and the protein corona of each type was analyzed using liquid chromatography-tandem mass spectrometry technology. In total, 115 and 48 plasma proteins from the rat were identified as being bound to negatively charged 20 nm and 100 nm SiO2 nanoparticles, respectively, and 50 and 36 proteins were found for 20 nm and 100 nm arginine-coated SiO2 nanoparticles, respectively. Higher numbers of proteins were adsorbed onto the 20 nm sized SiO2 nanoparticles than onto the 100 nm sized nanoparticles regardless of charge. When proteins were compared between the two charges, higher numbers of proteins were

  8. Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Jang K

    2017-03-01

    Full Text Available Kyungho Jang,1,2,* Min-Kyoung Kim,3,4,* Jaeseong Oh,1 SeungHwan Lee,1 Joo-Youn Cho,1 Kyung-Sang Yu,1 Tai Kiu Choi,3 Sang-Hyuk Lee,3,4 Kyoung Soo Lim4 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Center for Clinical Pharmacology and Biomedical Research Institute, Chonbuk National University Medical School, Jeonju, 3Department of Psychiatry, 4Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, Republic of Korea *These authors contributed equally to this work Purpose: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1 to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute respiratory distress syndrome, a severe complication of influenza; however, its influence on the pharmacokinetics (PK of oseltamivir is controversial. The aim of this study was to investigate the effects of coadministering oseltamivir and dexamethasone on the PK of oseltamivir in healthy volunteers. Methods: An open-label, two-period, one-sequence, multiple-dose study was conducted in 19 healthy male volunteers. Oseltamivir (75 mg was orally administered on Day 1 and Day 8, and dexamethasone (1.5 mg was administered once daily from Day 3 to Day 8. Serial blood and urine samples were collected for PK analysis of oseltamivir and oseltamivir carboxylate on Day 1 and Day 8. Oseltamivir and oseltamivir carboxylate concentrations in plasma and urine were determined using liquid chromatography–tandem mass spectrometry. Results: Area under the plasma concentration–time curve (AUC of oseltamivir and oseltamivir carboxylate decreased after dexamethasone treatment for 6 days. The geometric mean ratio (90% confidence interval of the metabolic ratio

  9. Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Yoon S

    2014-01-01

    Full Text Available Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER formulation with that of the reference immediate-release (IR formulation in the fasting state. The effect of food on the bioavailability of itopride ER was also assessed. Methods: A single-center, open-label, randomized, multiple-dose, three-treatment, three-sequence, crossover study was performed in 24 healthy male subjects, aged 22–48 years, who randomly received one of the following treatments for 4 days in each period: itopride 150 mg ER once daily under fasting or fed conditions, or itopride 50 mg IR three times daily in the fasting state. Steady-state pharmacokinetic parameters of itopride, including peak plasma concentration (Cmax and area under the plasma concentration versus time curve over 24 hours after dosing (AUC0–24h, were determined by noncompartmental analysis. The geometric mean ratio of the pharmacokinetic parameters was derived using an analysis of variance model. Results: A total of 24 healthy Korean subjects participated, 23 of whom completed the study. The geometric mean ratio and its 90% confidence interval of once-daily ER itopride versus IR itopride three times a day for AUC0–24h were contained within the conventional bioequivalence range of 0.80–1.25 (0.94 [0.88–1.01], although Cmax was reached more slowly and was lower for itopride ER than for the IR formulation. Food delayed the time taken to reach Cmax for itopride ER, but AUC0–24h was not affected. There were no serious adverse events and both formulations were

  10. Review: Margaret A. Morrison, Eric Haley, Kim Bartel Sheehan & Ronal E. Taylor (2002. Using Qualitative Research in Advertising: Strategies, Techniques, and Applications / Shay Sayre (2001. Qualitative Methods for Marketplace Research

    Directory of Open Access Journals (Sweden)

    Susanne Friese

    2004-01-01

    Full Text Available The review discusses two books, both covering very similar contents and addressing more or less the same audience. The book by SAYRE is about the use of qualitative method in marketplace research in general and is aimed at marketing students and practitioners; the book by MORRISON, HALEY, SHEEHAN and TAYLOR focuses more specifically on one area of mar­keting, namely advertising research. MORRISON et al. provide the more practical perspective, a fact that is also reflected in the writing style of the book. It is stimulating to read, even for readers fa­miliar with qualitative methods. It provides insights from the perspective of advertising agency plan­ners and demonstrates how qualitative methods are applied in a commercial context. SAYRE, in comparison, provides more details and builds her book around five theoretical perspectives. It is writ­ten by an academic for a largely academic audi­ence, containing all the basics that one needs to know when embarking on a qualitative research project. It differs from other qualitative method books in that the various steps along the way are illustrated by examples from the field of marketing. The book will, therefore, resonate well with mar­ket­ing students. Nonetheless, both books can be recommended as text books for qualitative method courses in marketing—SAYRE's book for market­ing students in general, and MORRISON et al.'s book for students specializing in the field of adver­tising. When used in a course where students conduct a small scale research project on their own, both books need to be supplemented by further readings or teacher input. Specifically, the sections on qualitative data analysis are too thin in MORRISON et al. and too broad in SAYRE in order to be useful to students without further explanation and training. Nonetheless, the two books are the best I have seen so far when it comes to selecting a book to be used in a qualitative method course for marketing students. URN: urn:nbn:de:0114-fqs0401258

  11. Comment on "Combination of cupric ion with hydroxylamine and hydrogen peroxide for the control of bacterial biofilms on RO membranes by Hye-Jin Lee, Hyung-Eun Kim, Changha Lee [Water Research 110, 2017, 83-90]".

    Science.gov (United States)

    Chen, Long; Peng, Ying; Tang, Min; Wu, Feng

    2017-07-01

    The methodology employed by Lee et al. to terminate their bactericidal assays was found to be flawed via our demonstrations. Briefly, EDTA or sulfite combining with cupric ion did not fully terminate, and instead even boosted the P. aeruginosa death. We therefore suggested them to seek for other means of reaction termination, such as the combination of buffering agent PBS and Cu(II)-complexing agent EDTA. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Oral vaccination with LcrV from Yersinia pestis KIM delivered by live attenuated Salmonella enterica serovar Typhimurium elicits a protective immune response against challenge with Yersinia pseudotuberculosis and Yersinia enterocolitica.

    Science.gov (United States)

    Branger, Christine G; Torres-Escobar, Ascención; Sun, Wei; Perry, Robert; Fetherston, Jacqueline; Roland, Kenneth L; Curtiss, Roy

    2009-08-27

    The use of live recombinant attenuated Salmonella vaccines (RASV) synthesizing Yersinia proteins is a promising approach for controlling infection by Yersinia species. In this study, we constructed attenuated Salmonella strains which synthesize a truncated form of LcrV, LcrV196 and evaluated the immune response and protective efficacy elicited by these strains in mice against two other major species of Yersinia: Yersinia pseudotuberculosis and Yersinia enterocolitica. Surprisingly, we found that the RASV strain alone was sufficient to afford nearly full protection against challenge with Y. pseudotuberculosis, indicating the likelihood that Salmonella produces immunogenic cross-protective antigens. In contrast, lcrV196 expression was required for protection against challenge with Y. enterocolitica strain 8081, but was not sufficient to achieve significant protection against challenge with Y. enterocolitica strain WA, which expressed a divergent form of lcrV. Nevertheless, we are encouraged by these findings to continue pursuing our long-term goal of developing a single vaccine to protect against all three human pathogenic species of Yersinia.

  13. Exercise for frail elders Exercise for frail elders Best-Martini Elizabeth Kim A Product Botenhagen-Di Genova Human Kinetics £24.50 0 73603 687 3 0736036873.

    Science.gov (United States)

    2003-09-01

    Department of Health Publications Free 208 pp This guide provides practical advice on how to obtain information, services and equipment. It is aimed at people who are older, disabled or who have mental health problems and those who support them. Copies are available in Braille, audio cassette, disk, large print and in a range of languages. Tel: 0800 555777. www.doh.gov.uk /disabledguide.

  14. Report on the KIMS-CNA Conference (2nd): The PLA Navy’s Build-Up and ROK-USN Cooperation, Held in Seoul, Korea on 20 November 2008

    Science.gov (United States)

    2009-02-01

    Kegan Paul International and The AEI Press, 1996), p. 274. See also his "China’s Push Through the South China Sea: The Interaction of Bureaucratic and...to " green /blue water" navy enable to secure its vast maritime territorial claims with modern combat capability. For long time, the Chinese navy...operational capability placed somewhat between "coastal defense" and "full ocean-going green water fleet." It is conceivable that the Chinese navy’s

  15. A 90-day study of sub-chronic oral toxicity of 20 nm positively charged zinc oxide nanoparticles in Sprague Dawley rats

    Directory of Open Access Journals (Sweden)

    Park HS

    2014-12-01

    Full Text Available Hark-Soo Park,1 Seon-Ju Kim,1 Taek-Jin Lee,1 Geon-Yong Kim,1 EunHo Meang,1 Jeong-Sup Hong,1 Su-Hyon Kim,1 Sang-Bum Koh,1 Seung-Guk Hong,1 Yle-Shik Sun,1 Jin Seok Kang,2 Yu-Ri Kim,3 Meyoung-Kon Kim,3 Jayoung Jeong,4 Jong-Kwon Lee,4 Woo-Chan Son,5 Jae-Hak Park61General Toxicology Team, Korea Testing and Research Institute, Seoul, 2Department of Biomedical Laboratory Science, Namseoul University, Cheonan, 3Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, 4National Institute of Food and Drug Safety Evaluation, Seoul, 5Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 6Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, KoreaPurpose: The study reported here was conducted to determine the systemic oral toxicity and to find the no-observed-adverse-effect level of 20 nm positively charged zinc oxide (ZnOSM,20(+ nanoparticles in Sprague Dawley rats for 90 days.Methods: For the 90-day toxicity study, the high dose was set as 500 mg per kg of body weight (mg/kg and the middle and low dose were set to 250 mg/kg and 125 mg/kg, respectively. The rats were held for a 14-day recovery period after the last administration, to observe for the persistence or reduction of any toxic effects. A distributional study was also carried out for the systemic distribution of ZnOSM,20(+ NPs.Results: No rats died during the test period. There were no significant clinical changes due to the test article during the experimental period in functional assessment, body weight, food and water consumption, ophthalmological testing, urine analysis, necropsy findings, or organ weights, but salivation was observed immediately after administration in both sexes. The total red blood cell count was increased, and hematocrit, albumin, mean cell volume, mean cell hemoglobin, and mean cell hemoglobin concentration were decreased significantly compared with

  16. ‘The’ pathway towards the elite level in Dutch basketball : A multidimensional and longitudinal study on the development of talented youth basketball players

    NARCIS (Netherlands)

    te Wierike, Sanne Cornelia Maria

    2016-01-01

    Veel jonge talentvolle basketballers hebben één doel voor ogen; de top halen in hun sport. Hoe de ontwikkeling van jonge speler tot aan volwassen basketballer verloopt, is onderzocht in het promotieonderzoek van Sanne te Wierike. Dit onderzoek is uitgevoerd bij Bewegingswetenschappen (UMCG,

  17. Through the Eyes of an Infant : The Early Development of Visual Scanning and Disengagement of Attention

    NARCIS (Netherlands)

    Hunnius, S.

    2005-01-01

    Sabine Hunnius bestudeerde de ontwikkeling van het kijkgedrag van baby's tussen de zes weken en zes maanden. Het kijkgedrag van een jonge baby onderscheidt zich sterk van dat van een volwassene. Zeer jonge baby’s kijken al wel naar dingen die zich binnen hun blikveld bevinden, hierbij komen echter

  18. 68 - 75 Galadanchi et al.c

    African Journals Online (AJOL)

    User

    Restricted HartreeFock (RHF) and Density Functional Theory (DFT) studies were carried out on the organic semi ... arrays), organic light emitting diodes (OLEDs), solar cells and low-cost devices (Kitamura,Arakawa, 2008;. Hwan et al.2004; Byoungnan,2008). Organic semiconductors are materials with semiconducting.

  19. 4. VII kell 17 avatakse Haapsalu Evald Okase muuseumis rahvusvaheline klaasinäitus...

    Index Scriptorium Estoniae

    2004-01-01

    Ühtlasi lõpevad II Haapsalu klaasipäevad "Maritima". Korraldaja Kai Koppel. Klaasi puhuvad Rait Parts, Robert Tannahill Kanadast, Sun Hwan Hong Koreast, Kai Koppel. Näitusel näeb eesti klaasikunstnike Mare Saare, Ivo Lille, Rait Präätsa jt. töid

  20. Third North Korean nuclear test: what is the state of the North's programme?

    International Nuclear Information System (INIS)

    Sitt, Bernard

    2013-02-01

    Two months ago, following North Korea's Unha-3 launch, which put a small satellite into orbit, this publication discussed the possibility of a third North Korean nuclear test. As expected, Pyongyang remained true to its traditional policy of provocation. With carefully calculated timing, it carried out a third nuclear test on 12 February, just hours after Barack Obama's State of the Union address, four days before former leader Kim Jong-il's birthday, and on the eve of the investiture of the new South Korean president on the 25 February. Moreover, the North Korean regime is billing this test as a riposte to the new round of sanctions adopted on by the Security Council on 22 January following the Unha-3 launch in December, as it announced on the 24 January. Yet, aside from the associated posturing, this test confirms, if more confirmation were needed, the North's determination to develop an effective nuclear deterrent. The use of the term miniaturisation is certainly in part a propaganda exercise (can actual miniaturisation be achieved after three nuclear tests, one or two of whose success is highly doubtful?). Nonetheless, North Korea has clearly made progress in developing a nuclear weapon and an intercontinental ballistic missile derived from the Taepodong-2, and has promised to carry out further ballistic launches. Without a doubt, even if the North is a long way from possessing what we would consider an operational nuclear capability, its determination has helped it to make progress, and the country shows no signs of wanting to change course. In light of this fact, what can the international community do beyond existing and future sanctions regimes? Doubtless very little. China, which continues to support the North and which has been known in the past to exert influence on Pyongyang, has expressed its firm displeasure as to the North's activities but appears to have no leverage over Kim Jong-un. The Six-Party talks have little chance of being revived, as North

  1. Still at Odds: The Japanese Abduction Issue and North Korea’s Circumvention

    Directory of Open Access Journals (Sweden)

    Anthony DiFilippo

    2013-05-01

    Full Text Available Durante las décadas de 1970 y 1980, Corea del Norte, o tal y como se la conoce oficialmente, la República Democrática Popular de Corea (RDPC, secuestró a una serie de ciudadanos japoneses. Este asunto, hoy por hoy todavía sin resolver, se ha politizado enormemente en Japón, en particular desde que el difunto Kim Jong-Il admitiese al anterior primer ministro japonés, Junichiro Koizumi que efectivamente la RDPC había secuestrado ciudadanos japoneses durante la Guerra Fría. Pyongyang sin embargo lleva desde hace un tiempo manteniendo que el asunto relativo a los secuestros quedó resuelto hace varios años, a la par que insiste en que Japón ha de pedir disculpas a la RDPC por la colonización de la Península de Corea. Por su parte, Tokio se mantiene firme en lo que respecta a la necesidad de resolver el problema de los secuestros, subrayando que es uno de los principales problemas que se oponen a la normalización de las relaciones Japón-Corea del Norte. En gran medida por la fuerte relación de seguridad que liga a Japón con los Estados Unidos, y que en los últimos años se ha tenido que enfrentar al desafío múltiple de los lanzamientos de misiles balísticos y los ensayos nucleares, este artículo también trata la cambiante postura de Washington en relación con el asunto de los secuestros.

  2. Hydrogen adsorption strength and sites in the metal organic framework MOF5: Comparing experiment and model calculations

    Science.gov (United States)

    Mulder, F. M.; Dingemans, T. J.; Schimmel, H. G.; Ramirez-Cuesta, A. J.; Kearley, G. J.

    2008-07-01

    Hydrogen adsorption in porous, high surface area, and stable metal organic frameworks (MOF's) appears a novel route towards hydrogen storage materials [N.L. Rosi, J. Eckert, M. Eddaoudi, D.T. Vodak, J. Kim, M. O'Keeffe, O.M. Yaghi, Science 300 (2003) 1127; J.L.C. Rowsell, A.R. Millward, K. Sung Park, O.M. Yaghi, J. Am. Chem. Soc. 126 (2004) 5666; G. Ferey, M. Latroche, C. Serre, F. Millange, T. Loiseau, A. Percheron-Guegan, Chem. Commun. (2003) 2976; T. Loiseau, C. Serre, C. Huguenard, G. Fink, F. Taulelle, M. Henry, T. Bataille, G. Férey, Chem. Eur. J. 10 (2004) 1373]. A prerequisite for such materials is sufficient adsorption interaction strength for hydrogen adsorbed on the adsorption sites of the material because this facilitates successful operation under moderate temperature and pressure conditions. Here we report detailed information on the geometry of the hydrogen adsorption sites, based on the analysis of inelastic neutron spectroscopy (INS). The adsorption energies for the metal organic framework MOF5 equal about 800 K for part of the different sites, which is significantly higher than for nanoporous carbon materials (˜550 K) [H.G. Schimmel, G.J. Kearley, M.G. Nijkamp, C.T. Visser, K.P. de Jong, F.M. Mulder, Chem. Eur. J. 9 (2003) 4764], and is in agreement with what is found in first principles calculations [T. Sagara, J. Klassen, E. Ganz, J. Chem. Phys. 121 (2004) 12543; F.M. Mulder, T.J. Dingemans, M. Wagemaker, G.J. Kearley, Chem. Phys. 317 (2005) 113]. Assignments of the INS spectra is realized using comparison with independently published model calculations [F.M. Mulder, T.J. Dingemans, M. Wagemaker, G.J. Kearley, Chem. Phys. 317 (2005) 113] and structural data [T. Yildirim, M.R. Hartman, Phys. Rev. Lett. 95 (2005) 215504].

  3. Mobile Phone Interventions for Sleep Disorders and Sleep Quality: Systematic Review.

    Science.gov (United States)

    Shin, Jong Cheol; Kim, Julia; Grigsby-Toussaint, Diana

    2017-09-07

    Although mobile health technologies have been developed for interventions to improve sleep disorders and sleep quality, evidence of their effectiveness remains limited. A systematic literature review was performed to determine the effectiveness of mobile technology interventions for improving sleep disorders and sleep quality. Four electronic databases (EBSCOhost, PubMed/Medline, Scopus, and Web of Science) were searched for articles on mobile technology and sleep interventions published between January 1983 and December 2016. Studies were eligible for inclusion if they met the following criteria: (1) written in English, (2) adequate details on study design, (3) focus on sleep intervention research, (4) sleep index measurement outcome provided, and (5) publication in peer-reviewed journals. An initial sample of 2679 English-language papers were retrieved from five electronic databases. After screening and review, 16 eligible studies were evaluated to examine the impact of mobile phone interventions on sleep disorders and sleep quality. These included one case study, three pre-post studies, and 12 randomized controlled trials. The studies were categorized as (1) conventional mobile phone support and (2) utilizing mobile phone apps. Based on the results of sleep outcome measurements, 88% (14/16) studies showed that mobile phone interventions have the capability to attenuate sleep disorders and to enhance sleep quality, regardless of intervention type. In addition, mobile phone intervention methods (either alternatively or as an auxiliary) provide better sleep solutions in comparison with other recognized treatments (eg, cognitive behavioral therapy for insomnia). We found evidence to support the use of mobile phone interventions to address sleep disorders and to improve sleep quality. Our findings suggest that mobile phone technologies can be effective for future sleep intervention research. ©Jong Cheol Shin, Julia Kim, Diana Grigsby-Toussaint. Originally published

  4. Estimation of health state utilities in breast cancer

    Directory of Open Access Journals (Sweden)

    Kim SH

    2017-03-01

    Full Text Available Seon-Ha Kim,1 Min-Woo Jo,2 Minsu Ock,2 Hyeon-Jeong Lee,2 Jong-Won Lee3,4 1Department of Nursing, College of Nursing, Dankook University, Cheonan, 2Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, 3Department of Breast and Endocrine Surgery, Asan Medical Center, Seoul, 4Department of Surgery, University of Ulsan College of Medicine, Seoul, South Korea Purpose: The aim of this study is to determine the utility of breast cancer health states using the standard gamble (SG and visual analog scale (VAS methods in the Korean general population.Materials and methods: Eight hypothetical breast cancer health states were developed based on patient education material and previous publications. Data from 509 individuals from the Korean general population were used to evaluate breast cancer health states using the VAS and the SG methods, which were obtained via computer-assisted personal interviews. Mean utility values were calculated for each human papillomavirus (HPV-related health state.Results: The rank of health states was identical between two valuation methods. SG values were higher than VAS values in all health states. The utility values derived from SG were 0.801 (noninvasive breast cancer with mastectomy and followed by reconstruction, 0.790 (noninvasive breast cancer with mastectomy only, 0.779 (noninvasive breast cancer with breast-conserving surgery and radiation therapy, 0.731 (invasive breast cancer with surgery, radiation therapy, and/or chemotherapy, 0.610 (locally advanced breast cancer with radical mastectomy with radiation therapy, 0.587 (inoperable locally advanced breast cancer, 0.496 (loco-regional recurrent breast cancer, and 0.352 (metastatic breast cancer.Conclusion: Our findings might be useful for economic evaluation of breast cancer screening and interventions in general populations. Keywords: breast neoplasm, Korea, quality-adjusted life years, quality of life

  5. Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway

    Directory of Open Access Journals (Sweden)

    Soni KK

    2017-10-01

    Full Text Available Kiran Kumar Soni,1,* Yu Seob Shin,1,* Bo Ram Choi,1 Keshab Kumar Karna,1 Hye Kyung Kim,2 Sung Won Lee,3 Chul Young Kim,4 Jong Kwan Park1 1Department of Urology, Chonbuk National University and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University, Jeonju, 2College of Pharmacy, Kyungsung University, Busan, 3Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University Medical School, Seoul, 4College of Pharmacy, Hangyang University, Ansan, Republic of Korea *These authors contributed equally to this work Abstract: Finasteride is used to treat male pattern baldness and benign prostatic hyperplasia. This study investigated the toxicity of finasteride and recovery by DA-9401 using Sprague Dawley (SD rats. Forty adult male SD rats were assigned to four groups: control (CTR, finasteride 1 mg/kg/day (F, finasteride 1 mg/kg + DA-9401 100 mg/kg/day (F + DA 100 and finasteride 1 mg/kg + DA-9401 200 mg/kg/day (F + DA 200. Treatments were by oral delivery once daily for 90 consecutive days. The gross anatomical parameters assessed included: genital organ weight; vas deferens sperm count and sperm motility; testosterone, dihydrotestosterone (DHT and malondialdehyde levels; and histological and terminal deoxynucleotidyl transferase enzyme mediated dUTP nick-end labeling (TUNEL staining of testis for spermatogenic cell density, Johnsen’s score and apoptosis. Testicular tissue was also used for evaluating endoplasmic reticulum (ER stress and apoptotic proteins. Epididymis weight, seminal vesicle weight, prostate weight, penile weight and vas deferens sperm motility showed significant differences between the F group and the CTR, F + DA 100 and F + DA 200 groups. There was no significant change in the testosterone level. DHT level decreased significantly in the F group compared with the CTR

  6. Relationship between cognitive insight and subjective quality of life in outpatients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Kim JH

    2015-08-01

    Full Text Available Jong-Hoon Kim,1 Seul Lee,1 Ah-Young Han,1 Kyungwook Kim,2 Jinyoung Lee1 1Neuroscience Research Institute, Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine, Gachon University, Incheon, Republic of Korea; 2Department of Medicine, Gachon University School of Medicine, Gachon University, Incheon, Republic of Korea Background: The concept of cognitive insight refers to the cognitive processes involved in patients’ re-evaluation of their anomalous experiences and of their misinterpretations. The purpose of the present study was to examine the relationship between cognitive insight and subjective quality of life in patients with schizophrenia to further shed light on the nature of cognitive insight and its functional correlates in schizophrenia.Methods: Seventy-one stable outpatients with schizophrenia were evaluated for cognitive insight and subjective quality of life using the Beck Cognitive Insight Scale (BCIS and the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4. The symptoms of schizophrenia were also assessed. Pearson’s correlation analysis and partial correlation analysis that controlled for the severity of symptoms were performed to adjust for the possible effects of symptoms.Results: The self-reflectiveness subscale score of the BCIS had significant positive correlations with the SQLS-R4 psychosocial domain and total SQLS-R4 scores, indicating that the higher the level of cognitive insight, the lower the subjective quality of life. In partial correlation analysis controlling for symptoms, the BCIS self-reflectiveness subscale score still had a significant correlation with the SQLS-R4 psychosocial domain score. The correlation coefficient between the BCIS self-reflectiveness and total SQLS-R4 scores was reduced to a nonsignificant statistical tendency.Conclusion: The results of our study suggest that cognitive insight, particularly the level of self-reflectiveness, is negatively associated with

  7. Sex differences in the effect of aging on dry eye disease

    Directory of Open Access Journals (Sweden)

    Ahn JH

    2017-08-01

    Full Text Available Jong Ho Ahn,1 Yoon-Hyeong Choi,2 Hae Jung Paik,1 Mee Kum Kim,3 Won Ryang Wee,3 Dong Hyun Kim1 1Department of Ophthalmology, Gachon University Gil Medical Center, 2Department of Preventive Medicine, Gachon University College of Medicine, Incheon, 3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea Purpose: Aging is a major risk factor in dry eye disease (DED, and understanding sexual differences is very important in biomedical research. However, there is little information about sex differences in the effect of aging on DED. We investigated sex differences in the effect of aging and other risk factors for DED.Methods: This study included data of 16,824 adults from the Korea National Health and Nutrition Examination Survey (2010–2012, which is a population-based cross-sectional survey. DED was defined as the presence of frequent ocular dryness or a previous diagnosis by an ophthalmologist. Basic sociodemographic factors and previously known risk factors for DED were included in the analyses. Linear regression modeling and multivariate logistic regression modeling were used to compare the sex differences in the effect of risk factors for DED; we additionally performed tests for interactions between sex and other risk factors for DED in logistic regression models.Results: In our linear regression models, the prevalence of DED symptoms in men increased with age (R=0.311, P=0.012; however, there was no association between aging and DED in women (P>0.05. Multivariate logistic regression analyses showed that aging in men was not associated with DED (DED symptoms/diagnosis: odds ratio [OR] =1.01/1.04, each P>0.05, while aging in women was protectively associated with DED (DED symptoms/diagnosis: OR =0.94/0.91, P=0.011/0.003. Previous ocular surgery was significantly associated with DED in both men and women (men/women: OR =2.45/1.77 [DED symptoms] and 3.17/2.05 [DED diagnosis], each P<0.001. Tests for

  8. Sleep and cognitive problems in patients with attention-deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Lee HK

    2014-09-01

    Full Text Available Hae Kook Lee, Jong-Hyun Jeong, Na-Young Kim, Min-hyeon Park, Tae-Won Kim, Ho-Jun Seo, Hyun-Kook Lim, Seung-Chul Hong, Jin-Hee Han Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea Objectives: Attention-deficit hyperactivity disorder (ADHD is characterized by inattentive and impulsive behavior. Many ADHD patients reportedly have cognitive dysfunction and sleep problems, including longer sleep latency, lower sleep efficiency, and shorter total sleep time. The purpose of this study was to examine neurocognitive functions and nocturnal sleep parameters in patients with ADHD, using a cognitive function test and actigraphy.Methods: Subjects included 37 male patients with ADHD and 32 controls (7–12 years of age. For each participant, we determined intelligence quotient (IQ and administered the Matching Familiar Figures Test (MFFT and 72-hour actigraphy. The relationships between sleep parameters and cognitive functions were assessed.Results: ADHD patients significantly differed from controls in several cognitive functions and sleep variables. In the MFFT, response error rate (P<0.001 and error counts (P=0.003 were significantly increased in ADHD patients compared with control children. MFFT response latency was significantly shorter in ADHD patients than in controls (P<0.001. In addition, sleep latency (P=0.01, wake after sleep onset (WASO (P<0.001, and fragmentation index (P<0.001 were evaluated by actigraphy and found to be significantly increased in patients with ADHD compared with controls. However, no significant differences in total sleep time or sleep efficiency were observed. WASO and response error rates were positively correlated in patients with ADHD (rho =0.52, P=0.012. Furthermore, fragmentation index sleep variables were significantly positively correlated with response error (rho =0.44, P=0.008 and response latency rates (rho =0.4, P=0.018 in the MFFT. Reaction error rate was significantly

  9. Dose-dependent effects of cisplatin on the severity of testicular injury in Sprague Dawley rats: reactive oxygen species and endoplasmic reticulum stress

    Directory of Open Access Journals (Sweden)

    Soni KK

    2016-12-01

    Full Text Available Kiran Kumar Soni,1 Hye Kyung Kim,2 Bo Ram Choi,1 Keshab Kumar Karna,1 Jae Hyung You,1 Jai Seong Cha,1 Yu Seob Shin,1 Sung Won Lee,3 Chul Young Kim,4 Jong Kwan Park1 1Department of Urology, Institute for Medical Sciences, Chonbuk National University Medical School – Biomedical Research and Institute and Clinical Trial Center for Medical Devices, Chonbuk National University Hospital, Jeonju, 2College of Pharmacy, Kyungsung University, Busan, 3Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University Medical School, Seoul, 4College of Pharmacy, Hanyang University, Ansan, Republic of Korea Abstract: Cisplatin (CIS is used in the treatment of cancer, but its nonspecific systemic actions lead to toxic effects on other parts of the body. This study investigated the severity of CIS toxicity by increasing its dose over a constant time period. Sprague Dawley rats were divided into five treatment groups and control group with CIS (2, 4, 6, 8, and 10 mg/kg administered intraperitoneally for 5 days. The body and organs were weighed, epididymal sperm was counted, and sperm motility and sperm apoptosis were evaluated. Blood samples were evaluated for complete blood count, reactive oxygen and nitrogen species, malondialdehyde levels, and total testosterone. The testicular tissue was examined for steroidogenic acute regulatory protein and endoplasmic reticulum stress protein. Epididymal sperm was collected for CatSper Western blot. The toxic effects of different doses of CIS on the testis and kidney were compared histologically. The weights of body, testis, epididymis, prostate, seminal vesicle, and kidney; sperm count; sperm motility; steroidogenic acute regulatory protein level; and epididymal sperm count were significantly lower in the CIS-treated groups than in the control group. In contrast, sperm apoptosis, plasma reactive oxygen and nitrogen species, and malondialdehyde, testosterone, red blood cell

  10. Regarding the influence of sex and aging on dry eye disease

    Directory of Open Access Journals (Sweden)

    Han SB

    2017-09-01

    Full Text Available Sang Beom HanDepartment of Ophthalmology, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, Republic of KoreaI read with great interest the article by Ahn et al1 entitled “Sex differences in the effect of aging on dry eye disease”, in which the authors revealed the sex differences in the effect of aging on dry eye disease (DED in Korean adult population. They also showed the differences in patterns of DED following ocular surgery according to sex.1 The large population-based cross-sectional study was undoubtfully well designed and conducted, and suggests that matching of age and sex is recommended in further researches on DED.1However, I would like to point out that there exist controversies regarding the effect of aging and sex on DED. Our previous study showed that age had no significant association with the prevalence of DED in adults of 65 years or older, while female sex was significantly related to increased prevalence of DED.2 By contrast, studies in the US demonstrated that prevalence of DED increased with aging both in male and female populations.3,4 Moreover, there are differences in pathophysiology of DED according to age. Although dysfunction of lacrimal and meibomian glands may play an important role in the pathogenesis of DED in the elderly, DED associated with visual display terminal use or contact lens wear is more common in young and middle-aged patients.5 Therefore, I believe these differences in the pathogenesis should be considered in the evaluation of the effects of sex and aging on DED.Authors' replyJong Ho Ahn,1 Yoon-Hyeong Choi,2 Hae Jung Paik,1 Mee Kum Kim,3 Won Ryang Wee,3 Dong Hyun Kim11Department of Ophthalmology, Gachon University Gil Medical Center, 2Department of Preventive Medicine, Gachon University College of Medicine, Incheon, 3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South KoreaWe thank the author for taking a

  11. Effect-site concentration of remifentanil for preventing cough during emergence in elderly patients undergoing nasal surgery: a comparison with adult patients

    Directory of Open Access Journals (Sweden)

    Yoo JY

    2016-09-01

    Full Text Available Ji Young Yoo,1 Jong Yeop Kim,1 Hyun Jeong Kwak,2 Dong Chul Lee,2 Go Wun Kim,1 Sook Young Lee,1 Yun Jeong Chae1 1Department of Anaesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, 2Department of Anaesthesiology and Pain Medicine, Gachon University, Gil Medical Center, Incheon, Korea Purpose: Prevention of cough during emergence after nasal surgery is important for avoiding surgical site bleeding. We investigated the remifentanil effect-site concentration in 50% (EC50 of the elderly patients undergoing nasal surgery for smooth emergence without cough and compared it with that of adult patients.Methods: Twenty-two elderly (aged 65–80 years and 25 adult patients (aged 20–60 years with an American Society of Anesthesiologists physical status I/II undergoing nasal surgery were enrolled. Anesthesia was maintained with sevoflurane and remifentanil. Remifentanil EC50 and EC95 for preventing cough were determined using the modified Dixon’s up-and-down method and isotonic regression with bootstrapping approach. Recovery profiles were also recorded.Results: With Dixon’s up-and-down method, the EC50 of remifentanil in elderly patients (2.40±0.25 ng/mL was not significantly different from that of adults (2.33±0.30 ng/mL (P=0.687. With isotonic regression, the EC95 of remifentanil in elderly patients (3.32 [95% confidence interval: 3.06–3.38] ng/mL was not significantly different from that of adults (3.30 [95% confidence interval: 2.96–3.37] ng/mL. However, eye opening time (14.1±3.8 vs 12.0±2.9 seconds, extubation time (17.2±4.1 vs 14.0±3.0 seconds, and postanesthesia care unit duration (44.5±7.6 vs 38.7±3.4 minutes in elderly patients were significantly longer than those in adults (P<0.05.Conclusion: Remifentanil EC50 for preventing cough after nasal surgery with sevoflurane anesthesia did not differ between elderly and adult patients. However, delayed awakening and respiratory adverse events may warrant attention

  12. A genetic screen of the mutations in the Korean patients with early-onset Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    An SS

    2016-12-01

    Full Text Available Seong Soo An,1,* Sun Ah Park,2,* Eva Bagyinszky,1 Sun Oh Bae,1 Yoon-Jeong Kim,2 Ji Young Im,2 Kyung Won Park,3 Kee Hyung Park,4 Eun-Joo Kim,5 Jee Hyang Jeong,6 Jong Hun Kim,7 Hyun Jeong Han,8 Seong Hye Choi,9 SangYun Kim10 1Department of Bionano Technology, Gachon University, Seongnam-si, 2Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon, 3Department of Neurology, Dong-A University College of Medicine and Institute of Convergence Bio-Health, Busan, 4Department of Neurology, Gachon University Gil Medical Center, Incheon, 5Department of Neurology, Pusan National University Hospital, Busan, 6Department of Neurology, Ewha Womans University Mokdong Hospital, Seoul, 7Department of Neurology, Ilsan Hospital, National Health Insurance Corporation, 8Department of Neurology, Myongii Hospital, Goyang, 9Department of Neurology, Inha University School of Medicine, Incheon, 10Department of Neurology, Seoul National University College of Medicine & Neurocognitive Behavior Center, Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea *These authors contributed equally to this work Abstract: Early-onset Alzheimer’s disease (EOAD has distinct clinical characteristics in comparison to late-onset Alzheimer’s disease (LOAD. The genetic contribution is suggested to be more potent in EOAD. However, the frequency of causative mutations in EOAD could be variable depending on studies. Moreover, no mutation screening study has been performed yet employing large population in Korea. Previously, we reported that the rate of family history of dementia in EOAD patients was 18.7% in a nationwide hospital-based cohort study, the Clinical Research Center for Dementia of South Korea (CREDOS study. This rate is much lower than in other countries and is even comparable to the frequency of LOAD patients in our country. To understand the genetic characteristics of EOAD in Korea, we screened the common Alzheimer’s disease (AD

  13. Randomised controlled trial of the efficacy of misoprostol used as a ...

    African Journals Online (AJOL)

    Randomised controlled trial of the efficacy of misoprostol used as a cervical ripening agent prior to termination of pregnancy in the first trimester. Eric T M de Jonge, Rachel Jewkes, Jonathan Levin, Helen Rees ...

  14. Traditsioonist ja uuendusest korea modernkunstis / Katrin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2005-01-01

    Souli galeriides ja muuseumides valitseb eeldatud kõrgtehnoloogilise kunsti asemel maalikunst. Pikemalt naiskunstnik Wook-kyung Choi (1940-1985) ja Jong-gu Lee näitustest ning soo- ja naisuuringute kongressist "Women's World 2005"

  15. Extraction and Purification of Flavonoids from Radix Puerariae

    African Journals Online (AJOL)

    and preparations are now on sale. ... significant for optimization of extraction, resin selection and ... and flavonoids as indexes, optimize the proper density. ..... system. Sep Purif Technol. 2008; 62: 590-595. 12. Chen JH, Liau BC, Jong TT.

  16. Key pluvial parameters in assessing rainfall erosivity in the south ...

    Indian Academy of Sciences (India)

    Monica Dumitraşcu

    2017-06-19

    Jun 19, 2017 ... models, such as the one proposed by Morgan, based on scoring ... 1997), EMMED model (De Jong et al. 1998), etc. ... Accord- ing to the World Health Organization (WHO ...... ural and technological hazards in urban ecosys-.

  17. Disgust propensity and disgust sensitivity : Separate constructs that are differentially related to specific fears

    NARCIS (Netherlands)

    van Overveld, W. J. M.; de Jong, P. J.; Peters, M. L.; Cavanagh, K.; Davey, G. C. L.

    Studies concentrating on interindividual differences in experiencing disgust have indicated that disgust propensity is associated with certain disorders, such as fear of blood and fear of spiders (de Jong & Merckelbach, 1998). However, current indices of disgust propensity suffer from conceptual

  18. Solid Foods: How to Get Your Baby Started

    Science.gov (United States)

    ... nutritional interventions. The Journal of Allergy and Clinical Immunology: In Practice. 2013;1:29. For consumers: Seven ... allergic diseases. The Journal of Allergy and Clinical Immunology. 2013;131:78. Kiefte-de Jong JC, et ...

  19. Raamaturappija / Karl Martin Sinijärv

    Index Scriptorium Estoniae

    Sinijärv, Karl Martin, 1971-

    1997-01-01

    Jong, Erica. Hirm viiekümnenda eluaasta ees; Tiigi, Liia. Pühadelaud; Talvet, Jüri. Eesti eleegia ja teisi luuletusi; Tolkien, John Ronald Reuel. Sõrmuse vennaskond. Sõrmuste isand; Masing, Uku. Mälestusi taimedest

  20. ␖Horsonality : a study on the personality of the horse

    NARCIS (Netherlands)

    Visser, E.K.

    2002-01-01

    Onderzoek naar de persoonlijkheidsstructuur van paarden. Er waren twee doelen: 1: kijken of persoonlijkheidseigeschappen van jonge paarden gekwantificeerd en 2: of deze persoonlijkheidseigenschappen de springeigenschappen van een paard op 3-jarige leeftijd kunnen voorspellen

  1. Sexual risky behaviour among Slovak adolescents and young adults : social and psychological factors

    NARCIS (Netherlands)

    Kalina, Ondrej

    2012-01-01

    Het centrale doel van dit proefschrift was om de relatie tussen seksueel risicovol gedrag (SRB) van adolescenten en jong volwassenen en gedragsfactoren verkennen (bijvoorbeeld het gebruik van alcohol, vorige seksueel gedrag), psychologische factoren (bv. extraversie, welzijn) en sociale factoren

  2. Literatuuronderzoek naar gegevens betreffende de betekenis van een aantal verwekkers van zoonosen in verband met de vleesconsumptie. VI: Yersinia enterocolitica

    NARCIS (Netherlands)

    Bos; J.M.; Engel; H.W.B.; Groothuis; D.G.; Knapen; F.van; Oosterom; J.; Weiss; J.W.

    1985-01-01

    Yersinia enterocolitica kan bij de mens aanleiding geven tot verschillende ziektebeelden. Het meest wordt de acute enterocolitis beschreven, vooral bij zeer jonge kinderen, maar daarnaast zijn ook de acute mesenteriale lymfadenitis en terminale ileitis (pseudoappendicitis) bekend. Dragerschap

  3. The fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices

    Directory of Open Access Journals (Sweden)

    Lee JA

    2015-03-01

    Full Text Available Jeong-A Lee,1,* Mi-Kyung Kim,1,* Hyoung-Mi Kim,2,* Jong Kwon Lee,3 Jayoung Jeong,4 Young-Rok Kim,5 Jae-Min Oh,2 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Wonju, Republic of Korea; 3Hazard Substances Analysis Division, Gwangju Regional Food and Drug Administration, Ministry of Food and Drug Safety, Gwangju, Republic of Korea; 4Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Chungcheongbuk-do, Republic of Korea; 5Department of Food Science and Biotechnology, Kyung Hee University, Yongin, Republic of Korea *These authors contributed equally to this work Background: Orally administered particles rapidly interact with biological fluids containing proteins, enzymes, electrolytes, and other biomolecules to eventually form particles covered by a corona, and this corona potentially affects particle uptake, fate, absorption, distribution, and elimination in vivo. This study explored relationships between the biological interactions of calcium carbonate particles and their biokinetics.Methods: We examined the effects of food grade calcium carbonates of different particle size (nano [N-Cal] and bulk [B-Cal]: specific surface areas of 15.8 and 0.83 m2/g, respectively on biological interactions in in vitro simulated physiological fluids, ex vivo biofluids, and in vivo in gastrointestinal fluid. Moreover, absorption and tissue distribution of calcium carbonates were evaluated following a single dose oral administration to rats.Results: N-Cal interacted more with biomatrices than bulk materials in vitro and ex vivo, as evidenced by high fluorescence quenching ratios, but it did not interact more actively with biomatrices in vivo. Analysis of coronas revealed that immunoglobulin, apolipoprotein, thrombin, and fibrinogen

  4. Organization of research team for nano-associated safety assessment in effort to study nanotoxicology of zinc oxide and silica nanoparticles

    Directory of Open Access Journals (Sweden)

    Kim YR

    2014-12-01

    Full Text Available Yu-Ri Kim,1,* Sung Ha Park,2,* Jong-Kwon Lee,3 Jayoung Jeong,3 Ja Hei Kim,4 Eun-Ho Meang,5 Tae Hyun Yoon,6 Seok Tae Lim,7 Jae-Min Oh,8 Seong Soo A An,9 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea; 2Department of Biochemistry, University of Bath, Bath, UK; 3Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungchungbuk-do, 4Consumers Korea, Chongro-ku, 5General toxicology team, Korea Testing and Research Institute, 6Laboratory of Nanoscale Characterization and Environmental Chemistry, Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul, 7Department of Nuclear Medicine, Chonbuk National University Medical School, Jeonju, Jellabuk-Do, 8Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Gangwon-do, 9Department of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, South Korea *Authors contributed equally to this work Abstract: Currently, products made with nanomaterials are used widely, especially in biology, biotechnologies, and medical areas. However, limited investigations on potential toxicities of nanomaterials are available. Hence, diverse and systemic toxicological data with new methods for nanomaterials are needed. In order to investigate the nanotoxicology of nanoparticles (NPs, the Research Team for Nano-Associated Safety Assessment (RT-NASA was organized in three parts and launched. Each part focused on different contents of research directions: investigators in part I were responsible for the efficient management and international cooperation on nano-safety studies; investigators in part II performed the toxicity evaluations on target organs such as assessment of genotoxicity, immunotoxicity, or skin penetration; and investigators in part III evaluated the toxicokinetics of NPs with newly developed

  5. IAEA Completes Nuclear Security Review Mission in Republic of Korea

    International Nuclear Information System (INIS)

    2014-01-01

    security, and the example given by the ROK strengthens the message about the value of applying the IAEA Security Guidance and the use of its advisory services,'' said Carlos Torres Vidal, Head of the IAEA Nuclear Security of Materials and Facilities Section. ''The IPPAS mission was very useful in improving the ROK's nuclear security regime. The Republic of Korea will implement the recommendations and suggestions in the near future, and we intend to invite a follow-up mission afterwards,'' said Kim Yong-Hwan, the Secretary General of NSSC. Background The mission was the 62nd IPPAS mission conducted by the IAEA since the programme began in 1995. The ROK was the 40th country which hosted an IPPAS mission. IPPAS missions are intended to help States strengthen their national nuclear security regime. The missions provide peer advice on implementing international instruments, and IAEA guidance on the protection of nuclear and other radioactive material and associated facilities. The missions call upon a team of international experts to assess a nation's system of physical protection, compare it with international best practices and make recommendations for improvement. IPPAS missions are conducted both on a nationwide and facility-specific basis. (IAEA)

  6. Tugevus ja nõrkus : loovus ja endised tööstusalad Hollandis = Strength and vulnerability : creativity and former indastrial sites in the Netherlands / Klaske Havik

    Index Scriptorium Estoniae

    Havik, Klaske, 1975-

    2005-01-01

    2003. a. septembris Amsterdamis toimunud konverentsist "Loovus ja linn" (peaesineja Richard Florida). Kasvulavade poliitikast. Westergasfabriek'i ümberkujundamisest (AB Mecanoo, Kathryn Gustafson), NDSM-i sadamakai kultuurikeskkonnaks kujundamisest (arhitektuuribürood loetletud) Amsterdamis, disainitehaseks renoveeritud Van Nelle tehasest (renoveerimist juhtis Wessel de Jonge, ruumikujundus: Claessens & Erdmann), ööklubist "Now & Wow" (arhitekt Marten de Jong, disainerid Robbert de Vrieze, Martijn van der Wiel), klubist "Las Palmas" Rotterdamis jm. Bibliograafia lk. 57

  7. Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups

    Directory of Open Access Journals (Sweden)

    Hong SC

    2011-12-01

    Full Text Available Seong Cheol Hong1,*, Jong Ho Lee1,*, Jaewook Lee1, Hyeon Yong Kim1, Jung Youn Park2, Johann Cho3, Jaebeom Lee1, Dong-Wook Han11Department of Nanomedical Engineering, BK21 Nano Fusion Technology Division, College of Nanoscience and Nanotechnology, Pusan National University, 2Department of Biotechnology Research, National Fisheries Research and Development Institute, Busan, 3Electronic Materials Lab, Samsung Corning Precision Materials Co, Ltd, Gumi City, Gyeongsangbukdo, Korea*These authors contributed equally to this workAbstract: Superparamagnetic iron oxide nanoparticles (SPIONs have been widely utilized for the diagnosis and therapy of specific diseases, as magnetic resonance imaging (MRI contrast agents and drug-delivery carriers, due to their easy transportation to targeted areas by an external magnetic field. For such biomedical applications, SPIONs must have multifunctional characteristics, including optimized size and modified surface. However, the biofunctionality and biocompatibility of SPIONs with various surface functional groups of different sizes have yet to be elucidated clearly. Therefore, it is important to carefully monitor the cytotoxicity and genotoxicity of SPIONs that are surfaced-modified with various functional groups of different sizes. In this study, we evaluated SPIONs with diameters of approximately 10 nm and 100~150 nm, containing different surface functional groups. SPIONs were covered with –O-groups, so-called bare SPIONs. Following this, they were modified with three different functional groups – hydroxyl (–OH, carboxylic (–COOH, and amine (–NH2 groups – by coating their surfaces with tetraethyl orthosilicate (TEOS, (3-aminopropyltrimethoxysilane (APTMS, TEOS-APTMS, or citrate, which imparted different surface charges and sizes to the particles. The effects of SPIONs coated with these functional groups on mitochondrial activity, intracellular accumulation of reactive oxygen species, membrane integrity

  8. Effectiveness of elastic band-type ankle–foot orthoses on postural control in poststroke elderly patients as determined using combined measurement of the stability index and body weight-bearing ratio

    Directory of Open Access Journals (Sweden)

    Kim JH

    2015-11-01

    Full Text Available Jong Hyun Kim, Woo Sang Sim, Byeong Hee Won Usability Evaluation Technology Center, Advanced Biomedical and Welfare R&D Group, Korea Institute of Industrial Technology, Cheonan-si, Chungcheongnam-do, South Korea Purpose: Poor recovery of postural stability poststroke is the primary cause of impairment in activities and social participation in elderly stroke survivors. The purpose of our study was to experimentally evaluate the effectiveness of our new elastic ankle–foot orthosis (AFO, compared to a traditional AFO fabricated with hard plastic, in improving postural stability in elderly chronic stroke survivors. Patients and methods: Postural stability was evaluated in ten chronic stroke patients, 55.7±8.43 years old. Postural stability was evaluated using the standardized methods of the Biodex Balance System combined with a foot pressure system, under three experimental conditions, no AFO, rigid plastic AFO, and elastic AFO (E-AFO. The following dependent variables of postural stability were analyzed: plantar pressure under the paretic and nonparetic foot, area of the center of balance (COB and % time spent in each location, distance traveled by the COB away from the body center, distance traveled by the center of pressure, and calculated index of overall stability, as well as indices anterior–posterior and medial–lateral stability. Results: Both AFO designs improved all indices of postural stability. Compared to the rigid plastic AFO, the E-AFO produced additional positive effects in controlling anterior–posterior body sway, equalizing weight bearing through the paretic and nonparetic limbs, and restraining the displacement of the center of pressure and of the COB. Conclusion: Based on our outcomes, we recommend the prescription of E-AFOs as part of a physiotherapy rehabilitation program to promote recovery of postural stability poststroke. When possible, therapeutic outcomes should be documented using the Biodex Balance System and

  9. Receptor-targeted, drug-loaded, functionalized graphene oxides for chemotherapy and photothermal therapy

    Directory of Open Access Journals (Sweden)

    Thapa RK

    2016-06-01

    Full Text Available Raj Kumar Thapa,1 Ju Yeon Choi,1 Bijay Kumar Poudel,1 Han-Gon Choi,2 Chul Soon Yong,1 Jong Oh Kim1 1College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongsanbuk-do, South Korea; 2College of Pharmacy, Hanyang University, Ansan, South Korea Abstract: Cancer is one of the leading causes of death worldwide. Although different chemotherapeutic agents have been developed to treat cancers, their use can be limited by low cellular uptake, drug resistance, and side effects. Hence, targeted drug delivery systems are continually being developed in order to improve the efficacy of chemotherapeutic agents. The main aim of this study was to prepare folic acid (FA-conjugated polyvinyl pyrrolidone-functionalized graphene oxides (GO (FA-GO for targeted delivery of sorafenib (SF. GO were prepared using a modified Hummer’s method and subsequently altered to prepare FA-GO and SF-loaded FA-GO (FA-GO/SF. Characterization of GO derivatives was done using ultraviolet/visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, atomic force microscopy, zeta potential measurements, and determination of in vitro drug release. Hemolytic toxicity, in vitro cytotoxicity, cellular uptake, and apoptotic effects of FA-GO/SF were also investigated. The results revealed that GO was successfully synthesized and that further transformation to FA-GO improved the stability and SF drug-loading capacity. In addition, the enhanced SF release under acidic conditions suggested possible benefits for cancer treatment. Conjugation of FA within the FA-GO/SF delivery system enabled targeted delivery of SF to cancer cells expressing high levels of FA receptors, thus increasing the cellular uptake and apoptotic effects of SF. Furthermore, the photothermal effect achieved by exposure of GO to near-infrared irradiation enhanced the anticancer effects of FA-GO/SF. Taken together, FA-GO/SF is a potential carrier for targeted delivery of chemotherapeutic agents in cancer

  10. Looking for nukes

    International Nuclear Information System (INIS)

    Albright, David

    2007-01-01

    How hard could it be to find hundreds of tons of radioactive nuclear material? We've certainly got plenty of motivation to keep tabs on this stuff. There's the threat of terrorist groups like Al Qaeda, the standoff between Pakistan's and India's arsenals and North Korea's Kim Jong II. Iran, the next big nuclear challenge, already has missiles that can strike Israel and a thriving civilian nuclear-power program. It claims to have no ambition for nuclear weapons, but verifying this is critical. We must know how much to press for a diplomatic solution or how seriously to consider a military strike. Nuclear intelligence, however, is problematic. Despite all the high-tech gear that intelligence agencies have developed, facts on the ground are so thin that the whole question of what countries like Iran are doing with nuclear weapons is vulnerable to manipulation by policymakers. Who can forget how Condoleezza Rice, as head of the National Security Council in September 2002, declared that the United States could not let the 'smoking gun' of Iraq's nuclear program become a mushroom cloud? Too often intelligence about clandestine nuclear programs is spotty and can easily be misread. Many people might think that technology allows spies to easily snoop on weapons plants, but that is not true. Satellite images can flag buildings suspected of being part of a nuclear-weapons program, but they cannot reveal what goes on inside. It's easy to hide a gas-centrifuge plant, which is needed to take ordinary uranium and turn it into highly enriched uranium for weapons. Spy-satellite photos of new construction at pre-1991 Iraqi nuclear-weapons sites helped convince the CIA that Iraq was building a uranium-enrichment plant. It turned out to be a repair shop for military radar, The chief evidence U.S. intelligence agents mustered on Iraq was a shipment of thousands of aluminum tubes thought to be key components of a gas centrifuge. Intercepted nuclear hardware and communications are

  11. Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers

    Directory of Open Access Journals (Sweden)

    Oh M

    2017-12-01

    Full Text Available Minkyung Oh,1,2,* Sung-Eun Park,3,* Jong-Lyul Ghim,1–3 Young-Kyung Choi,1 Eon-Jeong Shim,1–3 Jae-Gook Shin,1–3 Eun-Young Kim1–3 1Department of Pharmacology, 2PharmacoGenomics Research Center, Inje University College of Medicine, Busan, 3Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Busan, Republic of Korea *These authors contributed equally to this work Objective: This study compared the pharmacokinetic (PK and safety profiles of a fixed-dose combination (FDC formulation of telmisartan and S-amlodipine with those of concomitant administration of the two drugs.Materials and methods: This was an open-label, randomized, crossover study in healthy male Koreans. All subjects were administered an FDC tablet containing 40 mg telmisartan and 5 mg S-amlodipine and were also coadministered the same dose of both drugs given separately. The crossover study design included a 14-day washout period between the two treatments. Blood samples were collected up to 168 h following drug administration. The plasma concentrations of telmisartan and S-amlodipine were determined by liquid chromatography tandem mass spectrometry. PK parameters and plasma concentration–time curves were compared. Safety was assessed by measuring vital signs, clinical laboratory tests, physical examinations, and patient interviews.Results: The geometric mean ratios and 90% CIs for the maximum plasma concentration (Cmax and area under the curve from time zero to the last sampling time (AUCt were 0.8782 (0.8167–0.9444 and 0.9662 (0.9210–1.0136 for telmisartan and 1.0069 (0.9723–1.0427 and 1.0324 (0.9969–1.0690 for S-amlodipine, respectively. A total of 36 adverse events (AEs were reported by 23 subjects, but no statistical differences were observed between the two treatments. The most frequently reported AE was a mild-to-moderate headache that was generally self-limiting.Conclusion: For both telmisartan and S-amlodipine, the Cmax and AUCt 90% CIs

  12. Effects of anti-vascular endothelial growth factor monoclonal antibody (bevacizumab on lens epithelial cells

    Directory of Open Access Journals (Sweden)

    Jun JH

    2016-06-01

    Full Text Available Jong Hwa Jun,1 Wern-Joo Sohn,2 Youngkyun Lee,2 Jae-Young Kim21Department of Ophthalmology, School of Medicine, Dongsan Medical Center, Keimyung University, 2Department of Oral Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu, South KoreaAbstract: The molecular and cellular effects of anti-vascular endothelial growth factor monoclonal antibody (bevacizumab on lens epithelial cells (LECs were examined using both an immortalized human lens epithelial cell line and a porcine capsular bag model. After treatment with various concentrations of bevacizumab, cell viability and proliferation patterns were evaluated using the water-soluble tetrazolium salt assay and 5-bromo-2'-deoxyuridine enzyme-linked immunosorbent assay, respectively. The scratch assay and Western blot analysis were employed to validate the cell migration pattern and altered expression levels of signaling molecules related to the epithelial–mesenchymal transition (EMT. Application of bevacizumab induced a range of altered cellular events in a concentration-dependent manner. A 0.1–2 mg/mL concentration demonstrated dose-dependent increase in proliferation and viability of LECs. However, 4 mg/mL decreased cell proliferation and viability. Cell migrations displayed dose-dependent retardation from 0.1 mg/mL bevacizumab treatment. Transforming growth factor-β2 expression was markedly increased in a dose-dependent manner, and α-smooth muscle actin, matrix metalloproteinase-9, and vimentin expression levels showed dose-dependent changes in a B3 cell line. Microscopic observation of porcine capsular bag revealed changes in cellular morphology and a decline in cell density compared to the control after 2 mg/mL treatment. The central aspect of posterior capsule showed delayed confluence, and the factors related to EMT revealed similar expression patterns to those identified in the cell line. Based on these results, bevacizumab modulates the proliferation

  13. Self-perceived cognitive deficits and their relationship with internalized stigma and quality of life in patients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Shin YJ

    2016-06-01

    Full Text Available Yeon-Jeong Shin,1,2 Yo-Han Joo,1 Jong-Hoon Kim1–3 1Neuroscience Research Institute, 2Department of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, 3Department of Psychiatry, Gil Medical Center, Gachon University School of Medicine, Gachon University, Incheon, Republic of Korea Background: We investigated self-perceived cognitive deficits and their relationship with internalized stigma and quality of life in patients with schizophrenia in order to shed light on the clinical correlates of subjective cognitive deficits in schizophrenia.Methods: Seventy outpatients with schizophrenia were evaluated. Patients’ self-perceived cognitive deficits, internalized stigma, and subjective quality of life were assessed using the Scale to Investigate Cognition in Schizophrenia (SSTICS, the Internalized Stigma of Mental Illness Scale (ISMI, and the Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4, respectively. Correlation and regression analyses controlling for the severity of symptoms of schizophrenia were performed, and a mediation analysis was conducted to examine the hypothesis that internalized stigma mediates the relationship between self-perceived cognitive deficits and subjective quality of life.Results: Pearson’s partial correlation analysis showed significant correlations among the SSTICS, ISMI, and SQLS-R4 scores (P<0.01. Multiple regression analysis showed that the SSTICS and ISMI scores significantly predicted the SQLS-R4 score (P<0.01. Mediation analysis revealed that the strength of the association between the SSTICS and SQLS-R4 scores decreased from β=0.74 (P<0.01 to β=0.56 (P<0.01, when the ISMI score was statistically controlled. The Sobel test revealed that this difference was significant (P<0.01, indicating that internalized stigma partially mediated the relationship between self-perceived cognitive deficits and quality of life.Conclusion: The present study indicates that self

  14. Twelve-week, prospective, open-label, randomized trial on the effects of an anticholinergic agent or antidiuretic agent as add-on therapy to an alpha-blocker for lower urinary tract symptoms

    Directory of Open Access Journals (Sweden)

    Shin YS

    2014-07-01

    Full Text Available Yu Seob Shin,1 Li Tao Zhang,1 Chen Zhao,2 Young Gon Kim,1 Jong Kwan Park1 1Department of Urology, Chonbuk National University Medical School, and Institute for Medical Sciences, Chonbuk National University and Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University Hospital, Jeonju, South Korea; 2Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, and Shanghai Institute of Andrology, Shanghai, People’s Republic of China Purpose: The effects of an anticholinergic or antidiuretic agent as add-on therapy to an ­alpha-blocker for lower urinary tract symptoms (LUTS according to a voiding diary in 3 days are unknown. We prospectively investigated the efficacy of an anticholinergic or antidiuretic agent as add-on therapy for nocturia in men previously treated with an alpha-blocker for LUTS.Subjects and methods: Patients were randomly subdivided into two groups. All patients had a 4-week washout. Group A had alpha-blocker for 4 weeks, then an alpha-blocker plus an anticholinergic agent for 4 weeks, and, finally, 4 weeks of an alpha-blocker plus an antidiuretic agent. Group B had an alpha-blocker for 4 weeks, then an alpha-blocker plus an antidiuretic agent for 4 weeks, and, finally, 4 weeks of an alpha-blocker plus an anticholinergic agent. In both groups, patients were subdivided into nocturnal polyuria, decreased nocturnal bladder capacity (NBC, or nocturia by both causes subgroups. A 3-day voiding diary, total International Prostate Symptom Score (IPSS, IPSS sub-scores, Overactive Bladder Symptom Score, uroflowmetry, and post-void residual urine volume, were assessed at baseline, and at 4, 8, and 12 weeks.Results: A total of 405 patients completed the study. During treatment, the changes from baseline in total IPSS and IPSS sub-scores were significantly decreased at 4 weeks and were maintained for 12 weeks. In the nocturnal polyuria subgroup of Groups A and B

  15. Importance of Active Participation in Obesity Management Through Mobile Health Care Programs: Substudy of a Randomized Controlled Trial.

    Science.gov (United States)

    Oh, Bumjo; Yi, Ga-Hye; Han, Min Kyu; Kim, Jong Seung; Lee, Chang Hee; Cho, Belong; Kang, Hee Cheol

    2018-01-03

    passive group and 209 in the control group (without SmartCare service). There was a statistically significant difference in improvements to body weight, BMI, body fat percentage, and waist circumference among active participants compared with less active participants and the control group (Pservice, encouraging active participation is important. Clinicaltrials.gov NCT01344811; https://clinicaltrials.gov/ct2/show/NCT01344811 (Archived by WebCite at http://www.webcitation.org/6alT2MmIB). ©Bumjo Oh, Ga-Hye Yi, Min Kyu Han, Jong Seung Kim, Chang Hee Lee, Belong Cho, Hee Cheol Kang. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 03.01.2018.

  16. Photothermal-modulated drug delivery and magnetic relaxation based on collagen/poly(γ-glutamic acid hydrogel

    Directory of Open Access Journals (Sweden)

    Cho SH

    2017-03-01

    Full Text Available Sun-Hee Cho,1,* Ahreum Kim,1,* Woojung Shin,2 Min Beom Heo,1 Hyun Jong Noh,1 Kwan Soo Hong,3,4 Jee-Hyun Cho,3,4 Yong Taik Lim1,2 1SKKU Advanced Institute of Nanotechnology (SAINT, 2School of Chemical Engineering, Sungkyunkwan University, Suwon, 3Bioimaging Research Team, Korea Basic Science Institute, Cheongju, 4Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea *These authors contributed equally to this work Abstract: Injectable and stimuli-responsive hydrogels have attracted attention in molecular imaging and drug delivery because encapsulated diagnostic or therapeutic components in the hydrogel can be used to image or change the microenvironment of the injection site by controlling various stimuli such as enzymes, temperature, pH, and photonic energy. In this study, we developed a novel injectable and photoresponsive composite hydrogel composed of anticancer drugs, imaging contrast agents, bio-derived collagen, and multifaceted anionic polypeptide, poly (γ-glutamic acid (γ-PGA. By the introduction of γ-PGA, the intrinsic temperature-dependent phase transition behavior of collagen was modified to a low viscous sol state at room temperature and nonflowing gel state around body temperature. The modified temperature-dependent phase transition behavior of collagen/γ-PGA hydrogels was also evaluated after loading of near-infrared (NIR fluorophore, indocyanine green (ICG, which could transform absorbed NIR photonic energy into thermal energy. By taking advantage of the abundant carboxylate groups in γ-PGA, cationic-charged doxorubicin (Dox and hydrophobic MnFe2O4 magnetic nanoparticles were also incorporated successfully into the collagen/γ-PGA hydrogels. By illumination of NIR light on the collagen/γ-PGA/Dox/ICG/MnFe2O4 hydrogels, the release kinetics of Dox and magnetic relaxation of MnFe2O4 nanoparticles could be modulated. The experimental results suggest that

  17. Reklamların ve Cinsiyet Kimliği Rolünün Tüketicilerin Satın Alma Davranışları Üzerindeki Etkisi = The Effect of Advertisements and Gender Identity Role on Consumer Buying Behavior

    Directory of Open Access Journals (Sweden)

    Mehmet İsmail YAĞCI

    2010-01-01

    Full Text Available Gender is a segmentation criterion which has been used for a long time especially for the analyses of consumer behavior in traditional marketing. However an obligation has aroused to digress the traditional patterns in order to understand consumer behavior in our rapidly changing world. At this point, “gender identity role” concept which is frequently encountered in the literature reminded may help researchers in understanding complex consumer buying behavior. In this study, consumer’s gender identity’s impact on their response to advertisements and whether their socio-economic status levels’ effect their gender identities or not have been analyzed and some significant relations have been found.

  18. Informatics Observed [and] Agenda: A Tool for Agenda Setting Research [and] Telos Language Partner: Multimedia Language Learning, Authoring and Customisation [and] Towards a Consumer Perspective on Information Behaviour Research [and] The Digital Library as Access Management Facilitator [and] Knowledge and Information Management (KIM'21) [and] Perspectives of ICT in Professional Development and Education.

    Science.gov (United States)

    Cawkell, Tony; Kok, Yeong Haur; Goh, Angela; Holaday, Duncan; Hoffstaedter, Petra; Kohn, Kurt; Rowley, Jennifer; van Halm, Johan; Pye, Jo

    1999-01-01

    The following collection of articles reprinted from "CD ROM and Online Review" include "a new way of learning." Discuses research and development funding in educational technology and recommends to offer vast sums to investigate the best way of teaching a particular topic, and through that to fund the use of computers as an incidental part of the…

  19. 1942-1943 Arası Dönemde Kıbrıs Türk Kimliğinin İlk Kurumsallaşma Hareketleri Early Movements of Institutionalizing the Cypriot Turkish Identity Between 1942 and 1943

    Directory of Open Access Journals (Sweden)

    Sibel AKGÜN

    2012-09-01

    Full Text Available Cyprus has been occupying the agenda of international relationssince the mid-20th Century, and it still remains among the unsolvedproblems in the world. The island has a political history that is definedby contrasting interests and political demands in the EasternMediterranean. Apart from global and local balances, the main problem in Cyprus is the idea of nationalism that emerged mostly in 1878 and has crystallized in the process of ethnic differentiation between the two major ethnic and religious communities living in the island. This idea has been consolidated by the policies pursued by the British colonial administration and by the influences of local elites; and thus two conflicting identities emerged. How these two identities, whose objectives and methods are different from one another, firstly emerged in a serious manner is of importance in political-cultural-sociocultural terms. The factors that triggered these processes and helped them get institutionalized constitute an important issue that needs to be addressed as much as their origins. It was the 1940s when those organizations firstly formed, which would serve as social carriers in the fields of media and political and professional organization. This process, which was triggered by international developments, will be addressed by examining each of the organizations such as KATAK and Halkın Sesi. While addressing this process, whose institutional foundations were Enosis, British colonial administration policies and Cypriot Turkish nationalism; the developments of the time will also be taken into consideration. The main subject of the study, on the other hand, will be the dynamics and development of these foundations in the 1940s in terms of organization for the Cypriot Turkish community. Kıbrıs, 20. yüzyılın ortasından itibaren uluslararası ilişkileringündeminde olup, günümüzün çözümlenmemiş sorunlarından biriniteşkil etmektedir. Ada, Doğu Akdeniz’de birbirine karşıt çıkarların vesiyasi isteklerin belirlediği siyasi tarihi ile hareketli bir geçmişe sahiptir.Küresel ve bölgesel dengelerin dışında, Kıbrıs’ta asıl sorun, büyükölçüde 1878 yılından başlayan ve adanın iki büyük etnik ve dinsel halkıarasında, etnik farklılaşma süreci ile belirginleşmiş olan milliyetçilikolgusudur. Bu olguya, İngiliz sömürge yönetiminin izlediği politikalar veyerel seçkin denilen aydınlar ve elitlerin etkisi de eklenince birbirinekarşıt, çatışan bir kimlik ikiliği ortaya çıkmıştır. Amaçları ve yönelimlerifarklı olan bu kimliklerin, oluşma süreci dışında politik - kültürel -sosyo ekonomik olarak ciddi anlamda ilk ortaya çıkma süreçleriönemlidir. Bu süreci tetikleyen ve kurumsallaşmasına neden olanfaktörler, ilk oluşmaya başlama dönemleri kadar önemli ve üzerindedurulması gereken bir konudur.Kıbrıs Türk halkı içinde basın yayın, siyasi ve meslekiörgütlenme alanlarında birer sosyal taşıyıcı olan yapılarınoluşturulması 1940’lı yıllara denk gelmektedir. Uluslararasıgelişmelerin etkisi ile başlayan bu süreç, tek tek KATAK, Halkın Sesigibi sosyal taşıyıcı yapıların incelenmesi ile ele alınacaktır. Kurumsaltemelinde Enosis, İngiliz sömürge yönetimi politikaları ve Kıbrıs Türkmilliyetçiliği olan bu süreç ele alınırken, dönemin gelişmeleri de gözönünde bulundurularak bir çözümleme yapılacaktır. Ayrı ayrı elealınabilecek olan bu temellerin, Kıbrıs Türk halkı için kurumsallaşmaanlamında 1940’lı yıllardaki dinamiği ve gelişimi ise çalışmanın anakonusu olacaktır.

  20. Tracking Theory Building and Use Trends in Selected LIS Journals: More Research is Needed. A review of: Kim, Sung‐Jin, and Dong Y. Jeong. “An Analysis of the Development and Use of Theory in Library and Information Science Research Articles.” Library & Information Science Research 28.4 (Sept. 2006: 548‐62.

    Directory of Open Access Journals (Sweden)

    Carol Perryman

    2007-09-01

    Full Text Available Objective ‐ The authors measure theory incidents occurring in four LIS journals between 1984‐2003 in order to examine their number and quality and to analyze them by topic. A third objective, only identified later in the text of the study, was to compare theory development and use between Korean and international journals. Research questions asked include whether LIS has its own theoretical base as a discipline, and what characteristics the theoretical framework has.Design – Bibliometric study.Setting – Journal issues selected from four LIS journals for the time span from 1984 ‐ 2003.Subjects – Two international journals, Journal of the American Society for Information Science and Technology (JASIST and Library and Information Science Research (LISR were selected based on their high ranking in the Social Sciences Citation Index (SSCI impact factors. Two Korean journals, Journal of the Korean Society for Information Management (JKSIM and Journal of the Korean Society for Library and Information Science (JKSLIS were selected.Methods ‐ After having determined a definition of theory, and identifying different levels of theory, the authors set up rules for the identification of theory incidents, which are defined as “events in which the author contributed to the development or the use of theory in his/her own paper” (550. Content analysis of 1661 research articles was performed to measure theory incidents according to working definitions. Interrater reliability was ensured by conducting independent coding for “subfield classification, identification of theory incidents, and quality measurement” (555,using a sample of 199 articles (random selection not specified, achieving 94‐97% interrater reliability. Incidents, once identified, were evaluated for quality using Dubin’s “efficiency of law” criteria, involving measures of relatedness, directionality, co‐variation, rate of change, and “profundity,” defined as the depth to which theory is incorporated into the research study.Main Results ‐ 21.79% (n=362 of the articles contained theory incidents that were analyzed and evaluated. Trend measurement indicated an overall increase, although a slight decrease was shown in the year range 1993‐2003. International journals accounted for 61.33% of theory incidents, compared to 38.67% for the Korean journals. T‐testing showed that differences in means between Korean and international journals were not statistically significant. Topical theory areas were ranked by frequency. The top five areas were shown to be nearly identical between Korean and international journals. ANOVA was performed with significant results in the difference between efficiency ratings. Conclusion – The authors find that the overall proportion of theory incidents including both theory development and use increased through the 20‐year time span examined, and that LIS has established its own theoretical framework based upon the frequency of incidents.

  1. Fall proof: improving mobility and balance Elizabeth Best-Martini Fall proof: improving mobility and balance and Kim A Botenhagen-Di Genova Human Kinetics £24.50 0 73603 687 3 0736036873 Debra Rose Human Kinetics £38 0 73604 088 9 0736040889.

    Science.gov (United States)

    2003-09-01

    A structured balance and mobility-training programme specifically designed to reduce physical frailty and the rising incidence of falls among older people. This practical manual blends theory into practical applications and covers an introduction to the body systems, balance assessments and a discussion of contemporary motor learning principles. Tel: Customer Services 0113 255 5665. Email: hk@hkeurope.com.

  2. X-ray crystal structures of the pheromone-binding domains of two quorum-hindered transcription factors, YenR of Yersinia enterocolitica and CepR2 of Burkholderia cenocepacia: KIM et al.

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Youngchang [Midwest Center for Structural Genomics, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Structural Biology Center, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Chhor, Gekleng [Midwest Center for Structural Genomics, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Tsai, Ching-Sung [Department of Microbiology, Cornell University, Ithaca New York 14853; Fox, Gabriel [Department of Microbiology, Cornell University, Ithaca New York 14853; Chen, Chia-Sui [Department of Microbiology, Cornell University, Ithaca New York 14853; Winans, Nathan J. [Department of Microbiology, Cornell University, Ithaca New York 14853; Jedrzejczak, Robert [Structural Biology Center, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Joachimiak, Andrzej [Midwest Center for Structural Genomics, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Structural Biology Center, Biosciences, Argonne National Laboratory, Argonne Illinois 60439; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago Illinois 60637; Winans, Stephen C. [Department of Microbiology, Cornell University, Ithaca New York 14853

    2017-07-24

    The ability of LuxR-type proteins to regulate transcription is controlled by bacterial pheromones, N-acylhomoserine lactones (AHLs). Most LuxR-family proteins require their cognate AHLs for activity, and some of them require AHLs for folding and stability, and for protease-resistance. However, a few members of this family are able to fold, dimerize, bind DNA, and regulate transcription in the absence of AHLs; moreover, these proteins are antagonized by their cognate AHLs. One such protein is YenR of Yersinia enterocolitica, which is antagonized by N-3-oxohexanoyl-l-homoserine lactone (OHHL). This pheromone is produced by the OHHL synthase, a product of the adjacent yenI gene. Another example is CepR2 of Burkholderia cenocepacia, which is antagonized by N-octanoyl-l-homoserine lactone (OHL), whose synthesis is directed by the cepI gene of the same bacterium. Here, we describe the high-resolution crystal structures of the AHL binding domains of YenR and CepR2. YenR was crystallized in the presence and absence of OHHL. While this ligand does not cause large scale changes in the YenR structure, it does alter the orientation of several highly conserved YenR residues within and near the pheromone-binding pocket, which in turn caused a significant movement of a surface-exposed loop.

  3. Osman Turan'ın Siyasetçi Kimliği ve Yassıada'da Yargılanması (1954-1961 Political Identity Of Osman Turan And His Trial In Yassıada (1954-1961

    Directory of Open Access Journals (Sweden)

    Zehra ARSLAN

    2013-09-01

    Full Text Available Osman Turan entered politics as the parliamentarian of Trabzonfrom Democrat Party after the elections held on 2nd of May 1954. Hecontinued his service until 1960 coup d’etat. During his service, heexpressed that he did not approve some of the enforcements ofDemocrat Party, to which he was a member, such as making Kırşehir adistrict, arrangements at universities and cautions against theopposition during the speeches he gave in Grand National Assembly ofTurkey and party group. In the post-1960 coup d’etat period (27th ofMay, a Grand Jury was constituted which led the accusations madetowards DP members after the coup d’etat and some laws grantingextraordinary authorities were enacted. Osman Turan was not presentin the Assembly due to health problems which prevented him fromrating either favorably or unfavorably. His name was mentioned withthose of oppositions since he sometimes contradicted Menderes. Therewere even rumors that he would be expelled. However, Osman Turanpreferred to keep his battle within DP. He was arrested after coup d’etatand he gave his testimony on 30th of June in 1960 for the first time. Hewas put on trial within the scope of articles no. 141 and 146 fromTurkish Penal Code in the bylaw prepared by prosecution. The onlyaccusation made in the name of Osman Turan in the bylaw was theclaim that he received a certain amount of foreign currency. As a resultof evidence he provided in addition to his defense and investigation, itwas proven that the claims against him were unreal. He experiencedsome health problems during his arrest which lasted for 16.5 months.He could not attend all of the trials for he was being treated in thehospital located in garrison. Osman Turan was one of the 45 defendantswho were arrested due to violation of constitutional law on 15th ofSeptember 1961 and acquitted later on. 2 Mayıs 1954 seçimleri ile Demokrat Parti Trabzon Milletvekili olarak aktif siyasete atılan Osman Turan, 27 Mayıs 1960 Darbesi'ne kadar bu görevini sürdürmüştür. Milletvekilliği süresince mensubu bulunduğu Demokrat Partinin Kırşehir'in ilçe haline getirilmesi, üniversitelerde yapılan düzenlemeler, muhalefete karşı alınan tedbirler vb. uygulamalarını tasvip etmediğini TBMM ve parti grubunda yaptığı konuşmalarda dile getirmiştir. 27 Mayıs Darbesi sonrası DP mensuplarına yönelik suçlamaların başını çeken Tahkikat Encümeni oluşturulması ve bu encümene olağanüstü yetkiler veren kanunların çıkartılması sırasında da Osman Turan, sağlık problemleri nedeniyle mecliste bulunamamış dolayısı ile bu kanunlara lehte veya aleyhte oy vermemiştir. Menderes'le zaman zaman ters düştüğü için parti içerisinde adı, muhaliflerle birlikte anılmış hatta ihraç edileceği yönünde söylentiler ortaya atılmıştı. Fakat mücadelesini DP içerisinde sürdürme yolunu seçen Osman Turan, darbe ile birlikte tutuklanmış, ilk ifadesini de 30 Haziran 1960 tarihinde vermiştir. İddia makamı tarafından hazırlanan kararnamede, Türk Ceza Kanununun 141 ve 146ncı maddeleri kapsamında yargılanmıştır. Kararnamede Osman Turan'ın adının geçtiği tek suçlama ise bir miktar döviz aldığı iddiası olmuştur. Savunmasına ek olarak sunduğu deliller ve yapılan soruşturmalar sonucunda aleyhinde yapılan suçlamaların gerçek dışı olduğu kanıtlanmıştır. Toplam 16,5 ay tutukluluk döneminde sağlık problemleri yaşamış ve garnizondaki hastanede tedavi altına alındığı için duruşmaların tümüne iştirak edememiştir. Osman Turan, 15 Eylül 1961 tarihinde anayasayı ihlal suçundan tutuklu bulunup beraatına karar verilen 45 sanık arasında yer almıştır.

  4. Application of the Single Hardening Model in the Finite Element Program ABAQUS

    DEFF Research Database (Denmark)

    Jakobsen, Kim Parsberg

    model, developed by Lade and Kim (Kim & Lade 1988, Lade & Kim 1988a, Lade & Kim 1988b) is implemented as a user defined material module, UMAT, in the commercial finite element program, ABAQUS. The advantages of the Single Hardening Model Iie in its ability to predict elastic and plastic displacements...

  5. In situ rumen degradability characteristics of rice straw, soybean ...

    African Journals Online (AJOL)

    In situ rumen degradability characteristics of rice straw, soybean curd residue and peppermint (Mentha piperita) in Hanwoo steer (Bos Taurus coreanae). Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon ...

  6. Browse Title Index

    African Journals Online (AJOL)

    Items 6201 - 6250 of 11090 ... Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon. Vol 10, No 65 (2011), In vitro activity of certain antimicrobial agents in combination with Augouardia letestii hexane extracts against methicillin-resistant Staphylococcus ...

  7. EDITORIAL: Focus on Plasma Medicine

    Science.gov (United States)

    Morfill, G. E.; Kong, M. G.; Zimmermann, J. L.

    2009-11-01

    -pressure microwave plasmas in an N2 and O2 gas mixture M K Singh, A Ogino and M Nagatsu Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma H J Lee, C H Shon, Y S Kim, S Kim, G C Kim and M G Kong The acidification of lipid film surfaces by non-thermal DBD at atmospheric pressure in air A Helmke, D Hoffmeister, N Mertens, S Emmert, J Schuette and W Vioel Reduction and degradation of amyloid aggregates by a pulsed radio-frequency cold atmospheric plasma jet D L Bayliss, J L Walsh, G Shama, F Iza and M G Kong The effect of low-temperature plasma on bacteria as observed by repeated AFM imaging René Pompl, Ferdinand Jamitzky, Tetsuji Shimizu, Bernd Steffes, Wolfram Bunk, Hans-Ulrich Schmidt, Matthias Georgi, Katrin Ramrath, Wilhelm Stolz, Robert W Stark, Takuya Urayama, Shuitsu Fujii and Gregor Eugen Morfill Removal and sterilization of biofilms and planktonic bacteria by microwave-induced argon plasma at atmospheric pressure Mi Hee Lee, Bong Joo Park, Soo Chang Jin, Dohyun Kim, Inho Han, Jungsung Kim, Soon O Hyun, Kie-Hyung Chung and Jong-Chul Park Cell permeabilization using a non-thermal plasma M Leduc, D Guay, R L Leask and S Coulombe Physical and biological mechanisms of direct plasma interaction with living tissue Danil Dobrynin, Gregory Fridman, Gary Friedman and Alexander Fridman Nosocomial infections-a new approach towards preventive medicine using plasmas G E Morfill, T Shimizu, B Steffes and H-U Schmidt Generation and transport mechanisms of chemical species by a post-discharge flow for inactivation of bacteria Takehiko Sato, Shiroh Ochiai and Takuya Urayama Low pressure plasma discharges for the sterilization and decontamination of surfaces F Rossi, O Kylián, H Rauscher, M Hasiwa and D Gilliland Contribution of a portable air plasma torch to rapid blood coagulation as a method of preventing bleeding S P Kuo, O Tarasenko, J Chang, S Popovic, C Y Chen, H W Fan, A Scott, M Lahiani, P Alusta, J D Drake and M Nikolic A two

  8. Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation

    Directory of Open Access Journals (Sweden)

    Yousaf AM

    2015-03-01

    Full Text Available Abid Mehmood Yousaf,1 Dong Wuk Kim,1 Yu-Kyoung Oh,2 Chul Soon Yong,3 Jong Oh Kim,3 Han-Gon Choi11College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, 2College of Pharmacy, Seoul National University, Seoul, 3College of Pharmacy, Yeungnam University, Gyongsan, South KoreaBackground: The intention of this research was to prepare and compare various solubility-enhancing nanoparticulated systems in order to select a nanoparticulated formulation with the most improved oral bioavailability of poorly water-soluble fenofibrate.Methods: The most appropriate excipients for different nanoparticulated preparations were selected by determining the drug solubility in 1% (w/v aqueous solutions of each carrier. The polyvinylpyrrolidone (PVP nanospheres, hydroxypropyl-β-cyclodextrin (HP-β-CD nanocorpuscles, and gelatin nanocapsules were formulated as fenofibrate/PVP/sodium lauryl sulfate (SLS, fenofibrate/HP-β-CD, and fenofibrate/gelatin at the optimized weight ratios of 2.5:4.5:1, 1:4, and 1:8, respectively. The three solid-state products were achieved using the solvent-evaporation method through the spray-drying technique. The physicochemical characterization of these nanoparticles was accomplished by powder X-ray diffraction, differential scanning calorimetry, scanning electron microscopy, and Fourier-transform infrared spectroscopy. Their physicochemical properties, aqueous solubility, dissolution rate, and pharmacokinetics in rats were investigated in comparison with the drug powder.Results: Among the tested carriers, PVP, HP-β-CD, gelatin, and SLS showed better solubility and were selected as the most appropriate constituents for various nanoparticulated systems. All of the formulations significantly improved the aqueous solubility, dissolution rate, and oral bioavailability of fenofibrate compared to the drug powder. The drug was present in the amorphous form in HP-β-CD nanocorpuscles; however, in

  9. Prikaz knjige: Budislav Vukas, ml., Hrvatska državnost – pravnopovijesne prosudbe: uz 25. godišnjicu prijama Republike Hrvatske u Ujedinjene narode, Pravni fakultet Sveučilišta u Rijeci, Rijeka, 2017.

    Directory of Open Access Journals (Sweden)

    Mirela Krešić

    2018-01-01

    Full Text Available Godina 2017. u svjetskim je razmjerima bila iznimno dinamična godina. Obilježila su je različita zbivanja koja u našem globalnom selu imaju posvemašnji utjecaj bilo da je riječ o prirodnim katastrofama (uragani, požari, poplave i potresi ili onima na koje je znatno više utjecaja imala ljudska ruka, od terorističkih samoubilačkih napada, nuklearnog mahnitanja sjevernokorejskog vođe Kim Jong Una, neobičnog predsjednikovanja Donalda Trumpa ili, ako pogledamo bliže našem dvorištu, migrantskih valova, pokretanja postupka britanskog izlaska iz Europske unije te pokušaja katalonske vlade da izbori neovisnost od Španjolske. Istodobno tu su godinu u Hrvatskoj obilježile duboke društvene podjele, ideološke svađe te iseljavanje znatnog broja građana. Nezadovoljstvo koje hrvatski građani osjećaju i izražavaju prema stanju u državi, funkcioniranju njezinih institucija i pravcu u kojem zemlja ide daje nam pravo, ali nas i obvezuje, svakog pojedinačno i društvo u cjelini, upitati se što smo učinili u proteklih nemalih dva i pol desetljeća, odnosno jesmo li učinili dovoljno kako bismo opravdali stečenu neovisnost o kojoj su brojne generacije prije nas sanjale. Upravo je protek čak četvrt stoljeća od stjecanja neovisnosti bio poticaj prof. Budislavu Vukasu, mlađem da se u godini obilježavanja 25. godišnjice prijama Republike Hrvatske u Ujedinjene narode (22. svibnja, ali i obljetnice njezina međunarodnog priznanja (15. siječnja, pozabavi pitanjem hrvatske državnosti u prošlosti i njezinu kontinuitetu/diskontinuitetu kroz stoljeća. Rezultat njegova istraživanja je monografija Hrvatska državnost – pravnopovijesne prosudbe u izdanju Pravnog fakulteta Sveučilišta u Rijeci. Na 240 stranica teksta monografija daje autorovo viđenje “fenomena kontinuiteta hrvatske državnosti” (str. 9, pri čemu se na događanja s početka devedesetih godina prošlog stoljeća može gledati kao na svojevrsnu kulminaciju spomenutog

  10. The state of research after 25 years of Nanotechnology

    Science.gov (United States)

    Demming, Anna

    2013-01-01

    In 1990 the transistor was big—not just hugely prevalent in day-to-day devices but literally large in size compared with present day counterparts. Still, as Christoph Gerber describes in our latest Nanotechnology Discussions podcast [1], with transistor footprints decreasing every two years as described in Moore's law, by 1990 the electronics industry saw itself broaching new territory: nanotechnology. Atoms had made their debut as real-world observables with the first scanning probe microscopes only a few years previously, prompted by efforts to understand how physical systems behave at this scale. And in this heady climate of burgeoning nanoscale innovations Nanotechnology published its first issue, the world's first academic journal dedicated to nanoscale science and technology. This year the journal publishes its 25th volume and to celebrate we have commissioned a special issue presenting a snapshot of developments leading some of the most active areas in the field today [2]. As nanotechnology has matured both device-focused and fundamental research have placed high demands on improving fabrication processes to generate structures cheaply, efficiently and reliably. Since its discovery graphene has been under close scrutiny for the potential to exploit its optical transparency, mechanical flexibility and high carrier mobility. 'However', point out Ho Cho, Jong-Hyun Ahn and colleagues in Korea, 'it is still significantly challenging to develop clean and simple fabrication procedures'. They demonstrate how photo-curable ion gel gate dielectrics can be used to produce self-aligned flexible graphene transistors and inverters [3] simply without extra graphene-patterning steps. Sang Ouk Kim and colleagues at the Korea Advanced Institute of Science and Technology demonstrate another method for avoiding complex fabrication techniques, creating highly aligned graphene nanoribbon with their mussel-inspired block copolymer lithography and directed self-assembly [4

  11. Teratogenicity and brain aromatase-induction of monosodium ...

    African Journals Online (AJOL)

    Teratogenicity and brain aromatase-induction of monosodium glutamate in estrogen-responsive mosaic transgenic zebra fish Danio rerio. Tamer Said Abdelkader, Chang Seo-Na, Kim Tae-Hyun, Song Juha, Kim Dongso, Jae-Hak Park ...

  12. American Vitiligo Research Foundation

    Science.gov (United States)

    ... Place Vitiligo Voices Contact Welcome to The American Vitiligo Foundation Home Page Top Isabella T., California An ... 20.00 USD 20 for - 35.00 USD Vitiligo Doesn't Scare Me by Kim Kirkland Kim ...

  13. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... J Jia B M Johnson S C Johnson K S Joo S Kametani J H Kang M Kann S S Kapoor S Kelly B Khachaturov A Khanzadeev J Kikuchi D J Kim H J Kim S Y Kim Y G Kim W W Kinnison E Kistenev A Kiyomichi C Klein-Boesing S Klinksiek L Kochenda V Kochetkov D Koehler T Kohama D Kotchetkov A Kozlov P J Kroon K Kurita ...

  14. South African Gastroenterology Review - Vol 3, No 1 (2005)

    African Journals Online (AJOL)

    Identification of clinically-informative biomarkers for risk stratification within the spectrum of gastro-esophageal reflux disease in the South African population · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C van Rensburg, JNP de Villiers, C Daniels, C Wright, M Kidd, G de Jong, ...

  15. Testing causal models of job characteristics and employee well-being : a replication study using cross-lagged structural equation modelling

    NARCIS (Netherlands)

    Doest, ter L.; Jonge, de J.

    2006-01-01

    This study re-evaluated causal relationships between job characteristics (demands, autonomy, social support) and employee well-being (job satisfaction, emotional exhaustion) in a methodological replication of De Jonge et al.'s (2001) two-wave panel study. The principal difference was the 2-year time

  16. Workforce Issues.

    Science.gov (United States)

    1996

    This document consists of four papers presented during a symposium on work force issues moderated by Jan DeJong at the 1996 conference of the Academy of Human Resource Development (AHRD). "Rethinking the Ties that Bind: An Exploratory Study of Employee Development in Utilities in Canada and the United States" (Michael Aherne, David…

  17. Het geluid van de Beatles. Een muzieksociologische studie

    NARCIS (Netherlands)

    Tillekens, Gerardus Jacobus

    1998-01-01

    Het geluid van de Beatles. Er valt niet veel meer aan te doen. Met een soort emotionele superlijm zit het geluid van de Beatles en al die andere groepen van de Britse beatexplosie voor altijd verkleefd aan het beeld van de jaren zestig. Voor velen, zowel jong als oud kwam dat moment van culturele

  18. Marine Gastropods from Curaçao, Aruba and Bonaire

    NARCIS (Netherlands)

    Jong, de K.M.; Coomans, H.E.

    1988-01-01

    The present study is based on the well-known publication “Caribbean Seashells” by Warmke & Abbott (1961); its data are not repeated here, but a large number of mainly small species were added. Most data from “Gegevens over Mariene Gastropoden van Curaçao” by De Jong & Kristensen (1965) have been

  19. 9th state of logistics survey for South Africa: connecting neighbours - engaging the world

    CSIR Research Space (South Africa)

    Viljoen, N

    2013-06-01

    Full Text Available -1 Collaboration between CSIR, Imperial logistics and Stellenbosch University 9th state of logistics survey for South Africa: connecting neighbours - engaging the world Viljoen N, Bean W. Havenga J. Simpson Z. Jankauskaite Z. Gounder S. Steyn W. de Jonge G...

  20. BOEKBESPREKINGS P.P. BOOK REVIEWS

    African Journals Online (AJOL)

    LOCAL ANAESTHESIA. Physiology and Pharmacology oj Local Anesthesia. By R. H. de Jong, M.D. Pp. xiv + 267. Illustrated. $12.50. Spring- field, Ill.: Charles C. Thomas. 1970. This book fills a gap in anaesthetic literature. It is written in lucid style, with ideas logically, if repetitively developed with clear figures and useful ...

  1. South African Medical Journal - Vol 90, No 3 (2000)

    African Journals Online (AJOL)

    Randomised controlled trial of the efficacy of misoprostol used as a cervical ripening agent prior to termination of pregnancy in the first trimester · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Eric T M de Jonge, Rachel Jewkes, Jonathan Levin, Helen Rees, 256-261 ...

  2. Assortiment-kanaalmatch voor biologische fair tradeproducten

    NARCIS (Netherlands)

    LEI,

    2008-01-01

    Stichting FairBites ontwikkelt middels een innovatief organisatiemodel biologische en fair trade voedingsproducten voor de out-of-home (OOH) markt. Deze producten zijn zeer beperkt beschikbaar in dit marktsegment dat ± 35% van de voedingsmarkt vertegenwoordigd. FairBites richt zich op jong

  3. development in a basement terrain

    African Journals Online (AJOL)

    2004-05-17

    May 17, 2004 ... especially as a reconnaissance tool (de Jong et al., 1981; de. Rooy et al., 1986; ... ful naval radio transmitters in the very low frequency range. (15-25kHz). ... involved partial curve matching and computer iteration tech- niques. .... result predicted depth to fresh basement bedrock to be 46m whilst drilling ...

  4. Vocational education in the Netherlands: in search of a new identity

    NARCIS (Netherlands)

    Dr. Jan Geurts; dr. Frans Meijers

    2007-01-01

    When the Netherlands developed a national system of vocational education at the end of the 19th century, it was a direct answer to obvious shortcomings in the technical and trade professions (De Jonge, 1968). It concentrated on training craftsmen for the traditional, mainly agrarian economy, and

  5. Morfologische en functionele aspecten van de opslag en afgifte van insuline bij de ongeboren en pasgeboren rat

    NARCIS (Netherlands)

    Freie, Harm Maarten Paul

    1974-01-01

    Onderwerp van de in dit proefschrift beschreven onderzoekingen was de ontwikkeling van de insulineproducerende endocriene pancrreas bij de jonge rat in de periode voor en na de geboorte en de relaties tussen verschillende morfologische en functionele aspecten van deze ontwikkeling. Zie: Samenvatting

  6. Solid State Quantum Computer in Silicon

    Science.gov (United States)

    2008-09-30

    Zac Evans Martin Fuechsle Virginia Gill Toby Hopf Lenneke Jong Gajendran Kandasamy Wee Han Lim Graeme Lowe Melissa Makin Mladen Mitic Dane McCamey...Hudson 0.50 Linda Macks 0.50 Andrea Morello 1.00 Thilo Reusch 1.00 Frank Ruess 0.00 Giordano Scappucci 0.00 Laurens Willems van Beveren 0.60

  7. Starters slaan hun slag! : woningmarkt in de uitverkoop

    NARCIS (Netherlands)

    Francke, M.; van de Minne, A.

    2013-01-01

    Woningprijzen in Nederland dalen al sinds 2008. De gevolgen zijn groot: inmiddels staan naar schatting een miljoen huishoudens onder water. Echter, jonge huishoudens die nog willen starten op de koopwoningmarkt kunnen door de dalende woningprijzen en de lage hypotheekrente woningen kopen die

  8. Vormgeven aan loopbanen - De Talent Development Company

    NARCIS (Netherlands)

    Katinka Klop; Marlo Kengen

    2010-01-01

    Tijden van economische crisis vragen om nieuwe, creatieve vormen van personeelsvoorziening. Hoe behouden we ervaren vakmensen? En tegelijkertijd: Hoe winnen we jonge mensen voor onze sector? Hoe ontwikkelen we vakmensen in crisistijd? STAN heeft een concept ontwikkeld dat oplossingen moet bieden

  9. Auditory Weighting Functions and TTS/PTS Exposure Functions for Marine Mammals Exposed to Underwater Noise

    Science.gov (United States)

    2016-12-01

    male I’a nui hahai TYH WEN MUK, NOC female HF Jacobs and Hall, 1972 Kastelein et al., 2002** Kastelein, Hoek, de Jong, and Wensveen...Ridgway, S. H., D. A. Carder, T. Kamolnick, R. R. Smith, C. E. Schlundt, and W. R. Elsberry. 2001. “Hearing and Whistling in the Deep Sea: Depth

  10. Pain following primary total knee replacement: Causes, diagnosis and treatment

    NARCIS (Netherlands)

    van Geene, A.R.; Saris, Daniël B.F.; Custers, R.J.H.

    2015-01-01

    De plaatsing van een totale knieprothese (TKP) is een succesvolle ingreep bij patiënten met invaliderende gonartrose. Ondanks de goede resultaten is er een grote groep patiënten die niet tevreden is na de ingreep. Mannen, jonge patiënten en patiënten met chronische pijn zijn vaker tevreden na een

  11. Unifying Learning Object Repositories in MACE

    NARCIS (Netherlands)

    Prause, Christian; Ternier, Stefaan; De Jong, Tim; Apelt, Stefan; Scholten, Marius; Wolpers, Martin; Eisenhauer, Markus; Vandeputte, Bram; Specht, Marcus; Duval, Erik

    2007-01-01

    Prause, C., Ternier, S., De Jong, T., Apelt, S., Scholten, M., Wolpers, M., et al. (2007). Unifying Learning Object Repositories in MACE. In D. Massart, J.-N. Colin & F. V. Assche (Eds.). Proceedings of the First International Workshop on Learning Object Discovery & Exchange (LODE'07). September,

  12. Reference: 177 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 177 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u15722472i Al-Daoude ...lator of the plant disease resistance protein RPM1. 3 1016-28 15722472 2005 Mar The Plant cell Al-Daoude Antonious|Grant Murray|Ko Jong-Hyun|de Torres Zabala Marta

  13. Bestrijding van rouwmuggen en oevervliegen

    NARCIS (Netherlands)

    Pijnakker, J.; Leman, A.; Messelink, G.J.; Grosman, A.H.; Holstein, van R.

    2011-01-01

    Rouwmuggen zijn zeer algemeen in kassen, en meestal talrijker dan de typische plaag-insecten. De meeste soorten voeden zich met schimmels en met organisch materiaal, en zijn onschadelijke voor planten. Enkele soorten kunnen schadelijk zijn in zaaibedden, aan stekmateriaal en aan jonge planten. Veel

  14. In grote lijnen: Thema's in de natuurwetenschappen

    NARCIS (Netherlands)

    Weerdenburg, J.; Priem, H.N.A.; Hooff, J.A.R.A.M. van; Hoekstra, W.P.M.; Grind, W.A.P.F.L. van de

    Wie kent het verhaal niet? Van 1831-1836 maakte de jonge natuuronderzoeker Charles Robert Darwin een reis om de wereld mee op het Britse oorlogschip Beagle. Drieëntwintig jaar later publiceerde hij On the Origin of Species by Means of Natural Selection, waarin hij de theorie uitwerkt dat alle

  15. Tuut

    NARCIS (Netherlands)

    Blacquiere, T.

    2014-01-01

    Jonge net ‘geboren’ koninginnen tuten, de nog niet geboren koninginnen antwoorden met gekwaak. Dit behoort tot de standaard lesstof op de beginnerscursussen van de bijenhouders, en tot de meest tot de verbeelding sprekende verschijnselen in het bijenvolk. Niet in het minst vanwege de bekende

  16. Predictors and stages of very young child EFL learners’ English development in China

    NARCIS (Netherlands)

    Sun, He

    2015-01-01

    Het aantal zeer jonge taalleerders is sterk toegenomen in de wereld, maar studies over deze populatie zijn er weinig. Het huidige proefschrift neemt Chinese kleuters die Engels leren in China als focus, en bestudeert hun gedragsontwikkeling in de klas (op basis van twee case studies) en de

  17. Experiences with automated categorization in e-government information retrieval

    DEFF Research Database (Denmark)

    Jonasen, Tanja Svarre; Lykke, Marianne

    2014-01-01

    High-precision search results are essential for supporting e-government employees’ information tasks. Prior studies have shown that existing features of e-government retrieval systems need improvement in terms of search facilities (e.g., Goh et al. 2008), navigation (e.g., de Jong and Lentz 2006)...

  18. Behavioral therapy for functional constipation in childhood: health-related quality of life, emotional and behavior problems & parental child-rearing attitudes

    NARCIS (Netherlands)

    van Dijk, M.

    2011-01-01

    Kinderen met obstipatie worden behandeld met laxeermiddelen en krijgen gedragsadviezen (zoals toilettraining) en voorlichting. Toch houdt een derde van de patiënten tot in de jonge volwassenheid klachten. Marieke van Dijk vergeleek gedragstherapie in combinatie met laxatietherapie met de

  19. Stress speelt een belangrijke rol : inzicht in koploosheid groeit door gezamenlijk onderzoek

    NARCIS (Netherlands)

    Groot, S.P.C.; Kierkels, T.; Heuvelink, E.

    2016-01-01


    Jonge tomaten- en paprikaplanten, maar ook een aantal andere gewassen, houden soms opeens op met groeien. Koploosheid was lange tijd een lastig maar zeer slecht begrepen fenomeen. De laatste jaren is het inzicht in een stroomversnelling gekomen. In ieder geval is het aantal mogelijke oorzaken

  20. Orthopterological notes IV Notes on Indomalayan and African Pterophyl-Linae (Tettigoniidae)

    NARCIS (Netherlands)

    Jong, de C.

    1960-01-01

    The present paper contains a number of new facts concerning Indomalayan Pterophyllinae, which came to my attention after the publication of my first paper on this subfamily (De Jong, 1938 1))· Further it contains the description of new species: Cymatomera blötei and Tegrolcinia karnyi, an allotype:

  1. Religiosity and Premarital Sexual Permissiveness: A Response to the Reiss-Heltsley and Broderick Debate

    Science.gov (United States)

    Ruppel, Howard J., Jr.

    1970-01-01

    When religiosity among college students was measured by Faulkner and DeJong's 5-D Scale of Religiosity" and the Reiss scale was used to measure permissiveness, the expected stronger relationship between religiosity and permissiveness in groups with traditions of low sexual permissiveness than in groups with traditions of high sexual…

  2. Sexually transmitted infections, including HIV, in the Netherlands in 2008

    NARCIS (Netherlands)

    Koedijk FDH; van Veen MG; Op de Coul ELM; van den Broek IVF; van Sighem AI; Verheij RA; van der Sande MAB; LIS

    2009-01-01

    Chlamydia, gonorroe, syfilis. Na een stabilisatie van het percentage positieve chlamydiatesten in 2007, is dit in 2008 weer toegenomen. Vooral onder jonge heteroseksuelen en bij mannen die seks hebben met mannen (MSM) komt chlamydia veel voor. Het percentage positieve gonorroe- en syfilistesten

  3. De oudere werknemer in onregelmatige dienst : een praktijkstudie naar de beleving van verschillende roosterdiensten door ouderen vs jongeren

    NARCIS (Netherlands)

    Groenesteijn, L.; Looze, M.P. de

    2010-01-01

    TNO onderzocht bij een bedrijf waar veel ouderen werken, hoe de werkroosters verbeterd kunnen worden opdat oudere werknemers langer gezond en productief kunnen doorwerken. Jong en oud bleken het meest tevreden te zijn over de dagdienst en het rooster met alleen ochtend- en middagdienst zonder

  4. Epidemiological characteristics of oral and oropharyngeal squamous cell carcinoma

    NARCIS (Netherlands)

    van Monsjou, H.

    2015-01-01

    In de afgelopen decennia zijn er opmerkelijke veranderingen opgetreden in de epidemiologie van het plaveiselcelcarcinoom in het hoofd-halsgebied (HNSCC). Naast de typische HNSCC patiënt (man, 60-70 jaar, nicotine- en alcohol-abusus) is er meer aandacht gekomen voor de jonge HNSCC patiënt (<40-45

  5. The Growing Relationship Between South Korea and China: Consequences for North Korea

    Science.gov (United States)

    2006-03-01

    vassal state. Korean kings only “rendered obeisance” to China because it “signified their cultural respect for China as the center of…the civilized...Korea Game," Far Eastern Economic Review 163, no. 24 (Jun 15 2000): 16. The authors are quoting Lee Jong Seok, a senior Pyongyang watcher at Sejong

  6. Novel diagnostic and therapeutic targets in Marfan syndrome

    NARCIS (Netherlands)

    Radonić, T.

    2012-01-01

    Het Marfansyndroom is een erfelijke aandoening van het bindweefsel, met als belangrijkste kenmerk een verwijding van de aorta (hoofdslagader) die tot een plotse dood op jonge leeftijd kan leiden. De groeifactor TGF-β speelt daarbij een belangrijke rol. Teodora Radonic onderzocht of losartan, een

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1953-04-01

    Full Text Available - G.J. Held, P.E. de Josselin de Jong, Minangkabau and Negri Sembilan; Socio-political structure in Indonesia, 1951, PhD thesis, Leiden, viii + 208 pp. H.Th. Fischer, C. Nooteboom, Trois problèmes d'ethnologie maritime, 1952, Rotterdam: Museum van Land- en Volkenkunde, 25 figuren.

  8. #MeToo en seksueel grensoverschrijdend gedrag van scholieren

    NARCIS (Netherlands)

    Kocken, P.L.; Lijster, G. de; Ridder, J. de

    2018-01-01

    Seksueel grensoverschrijdend gedrag in onder andere de amusementswereld doet al enkele maanden stof opwaaien. Vrouwen die te maken hebben gehad met seksueel geweld of ongewenst gedrag, geven met #MeToo op Twitter en Facebook een statement af dat grenzen zijn bereikt en overschreden. Al op jonge

  9. Loneliness of older immigrant groups in Canada: Effects of ethnic-cultural background

    NARCIS (Netherlands)

    de Jong-Gierveld, J.; van der Pas, S.; Keating, N.

    2015-01-01

    This study aimed to explore the loneliness of several groups of older immigrants in Canada compared to native-born older adults. Data from the Canadian General Social Survey, Cycle 22 (N older adults = 3,692) were used. The dependent variable is the 6 item De Jong Gierveld loneliness scale.

  10. Campus Memories: Learning with Contextualised Blogging

    NARCIS (Netherlands)

    De Jong, Tim; Al Takrouri, Bashar; Specht, Marcus; Koper, Rob

    2006-01-01

    De Jong, T., Al Takrouri, B., Specht, M., Koper, R. (2007). Campus Memories: Learning with Contextualised Blogging. In D. Griffiths, R. Koper & O. Liber (Eds). Proceedings of The 2nd TenCompetence Workshop (pp. 59-67), January 11-12, 2007, Manchester, United Kingdom.

  11. The Interface Between Fresh and Salt Groundwater in Horizontal Aquifers : The Dupuit–Forchheimer Approximation Revisited

    NARCIS (Netherlands)

    van Duijn, C. J.; Schotting, R. J.

    We analyze the motion of a sharp interface between fresh and salt groundwater in horizontal, confined aquifers of infinite extend. The analysis is based on earlier results of De Josselin de Jong (Proc Euromech 143:75–82, 1981). Parameterizing the height of the interface along the horizontal base of

  12. The interface between fresh and salt groundwater in horizontal aquifers : the Dupuit–Forchheimer approximation revisited

    NARCIS (Netherlands)

    van Duijn, C. J.; Schotting, R. J.

    2017-01-01

    We analyze the motion of a sharp interface between fresh and salt groundwater in horizontal, confined aquifers of infinite extend. The analysis is based on earlier results of De Josselin de Jong (Proc Euromech 143:75–82, 1981). Parameterizing the height of the interface along the horizontal base of

  13. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. W-P Sung. Articles written in Sadhana. Volume 34 Issue 3 June 2009 pp 421-437. A model for signal processing and predictive control of semi-active structural control system · M-H Shih W-P Sung Ching-Jong Wang · More Details Abstract Fulltext PDF. The theory for structural control has been ...

  14. A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks

    NARCIS (Netherlands)

    De Jong, Tim; Fuertes, Alba; Schmeits, Tally; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong, T., Fuertes, A., Schmeits, T., Specht, M., & Koper, R. (2009). A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks. In D. Goh (Ed.), Multiplatform E-Learning Systems and Technologies: Mobile Devices for Ubiquitous ICT-Based Education (pp.

  15. Kniphoogte en ingebogen blad beïnvloeden uitloop roos

    NARCIS (Netherlands)

    Baas, R.

    2005-01-01

    Verschil in uitloop van jonge scheuten bij roos wordt vooral bepaald door variatie van het uitgangsmateriaal. Dit bepaalt de snelheid van uitlopen en de grootte van de griffeltak. Hoe groter de griffel, hoe meer en zwaarder de volgende scheuten. Hoog knippen zorgt voor een snellere uitloop

  16. Teacher competencies for working with young talent : part 2: integration of arts disciplines

    NARCIS (Netherlands)

    Kors, Ninja; Rickels, Horst; Smilde, Rineke; Verkuil, Marinus

    2007-01-01

    Twenty sixteen year old fourth-graders of the School for Young Talent (School voor Jong Talent) in The Royal Academy of Fine Arts, Design, Music and Dance (Hogeschool van Beeldende Kunsten, Muziek en Dans) participated in a pilot project that combined music, dance and visual arts in a creative

  17. “Fruit fight”: Leedvermaak en “Word-of-Mouth” bij consumentengroepen

    NARCIS (Netherlands)

    Vonkeman, C.C.; Ouwerkerk, J.W.; Van Dijk, Wilco W.

    2011-01-01

    Een onderzoek onder jonge BlackBerry-gebruikers toont aan dat domeinrelevantie en sociale identificatie met de eigen consumentengroep een interactieve bijdrage leveren aan de voorspelling van de mate van leedvermaak die zij ervaren om gebruikers van Apple’s iPhone na negatieve berichtgeving over dit

  18. Research

    African Journals Online (AJOL)

    abp

    2015-01-27

    Jan 27, 2015 ... 3. Ferrajolo C, Verhamme KM, Trifirò G, 't Jong GW, Giaquinto C,. Picelli G, Oteri A, de Bie S, Valkhoff VE, Schuemie MJ,. Mazzaglia G, Cricelli C, Rossi F, Capuano A, Sturkenboom MC. Idiopathic acute liver injury in paediatric outpatients: incidence and signal detection in two European countries. Drug Saf.

  19. Slumping of brine mounds : bounds on behaviour

    NARCIS (Netherlands)

    Philips, J.R.; Duijn, van C.J.

    1996-01-01

    Two modifications of the approximate analysis of interface motion during two-fluid density-driven flows of De Josselin de Jong (Proc. Euromech., 143: 75–82, 1981) are applied to the slumping of finite two-dimensional and axisymmetric brine mounds. Both lead to simple similarity solutions. One

  20. Slimme strategieën tegen schade door koolmot

    NARCIS (Netherlands)

    Leeuwen, van W.K.

    2007-01-01

    De rupsen van de koolmot zijn geen grote eters maar als ze in grote aantallen voorkomen kunnen ze flinke schade aanrichten. Vooral jonge koolgewassen en uitgroeiende spruiten moeten het daarbij ontgelden. Er zijn enkele strategieën waarmee koolmot beheerst kan worden: afdekken van het gewas,

  1. Democracy, globalization and ethnic violence

    NARCIS (Netherlands)

    Bezemer, D.J.; Jong-A-Pin, R.

    Bezemer, Dirk, and Jong-A-Pin, Richard Democracy, globalization and ethnic violence Do democratization and globalization processes combine to increase the incidence of violence in developing and emerging economies? The present paper examines this hypothesis by a study of internal violence in

  2. Identification and characterization of Brucella effector proteins

    NARCIS (Netherlands)

    de Jong, Maarten Frederik

    2012-01-01

    Brucella-bacteriën gebruiken de eiwitten VceB en VceC om het immuunsysteem van humane gastheercellen te omzeilen, blijkt uit het promotieonderzoek van Maarten de Jong. Dit biedt nieuwe aanknopingspunten voor de bestrijding van deze gevaarlijke bacterie. Brucellose is een wereldwijd voorkomende

  3. Ethics in action: Approving and improving medical research with human subjects

    NARCIS (Netherlands)

    de Jong, J.P.

    2013-01-01

    In this thesis, Jean Philippe de Jong presents a new understanding of ethical oversight on medical research with human subjects and proposes that two philosophies for ethical oversight exist: '(dis)approving' and 'improving'. Systems for ethical oversight on medical research have been in place for

  4. Educator Language Ideologies and a Top-Down Dual Language Program

    Science.gov (United States)

    Fitzsimmons-Doolan, Shannon; Palmer, Deborah; Henderson, Kathryn

    2017-01-01

    Dual language bilingual education (DLBE) programs are framed to reflect pluralist discourses (de Jong, E. [2013]. "Policy Discourses and U.S. Language in Education Policies." "Peabody Journal of Education" 88 (1): 98-111) and affiliated language ideologies. The continued expansion of DLBE programs not surprisingly brings to…

  5. '"Crazy Mina" guerrillas hit Holland." Transfer van Dolle Mina's ludieke acties' van en naar de VS (1968-1970)'

    NARCIS (Netherlands)

    Geerlings, A.J.M.

    2014-01-01

    Zaterdagavond 24 januari 1970, kwart over negen ’s avonds. Het tv-programma Brandpunt zond een item uit over actiegroep Dolle Mina. Jonge meiden die opriepen tot een kookstaking, die mannen nafloten op straat en een korset verbrandden. Vier miljoen mensen zaten die avond aan de buis gekluisterd en

  6. Een toekomst voor outdoor fitness in Nederland?

    NARCIS (Netherlands)

    Wiggers, Hiske

    De eerste kennismaking met outdoor fitness was in het Fuxing Park in Shanghai, een park waar jong en oud samen komen om te sporten (outdoor fitness, dans en tai-chi) of om ontspannen hun vrije dag door te brengen. een unieke ervaring die verwarring en allerlei vragen tot gevolg had. waarom komen

  7. Een helpende hand? De rol van discriminatie bij het hulpgedrag van kinderen

    NARCIS (Netherlands)

    Sierksma, J.

    2016-01-01

    Kinderen zijn heel prosociaal ingesteld en vinden het belangrijk om anderen te helpen. Zo zijn kinderen op de jonge leeftijd van 14 maanden al gemotiveerd om anderen te hulp te schieten, bijvoorbeeld door gevallen pennen op te rapen of door een kastje voor iemand open te doen die zijn of haar handen

  8. THE HEIDELBERG CATECHISM AND THE CHURCH

    African Journals Online (AJOL)

    in the CMa 125 the ministry of the gospel as human contribution is added. We conclude with the .... the main manual for instruction of the Christian faith, also on the church. It is remarkable that leading .... De Jong, r. 2013. Trouw. [Online.] ...

  9. Transmissie van Mycobacterium bovis tussen mens en dier

    NARCIS (Netherlands)

    Vries, de G.; Beer, de J.; Bakker, D.; Soolingen, D.

    2015-01-01

    Nederland is officieel vrij van rundertuberculose. Toch komt af en toe nog Mycobacterium bovis-tuberculose voor bij relatief jonge autochtone Nederlanders. Ook zijn er recent nog wel boviene-uitbraken geweest. Dat roept de vraag op of er ook nu nog transmissie is van M.bovis tussen mens en dier.

  10. Pepino mozaïekvirus; een blijvend probleem??

    NARCIS (Netherlands)

    Stijger, I.; Vlugt, van der R.A.A.

    2006-01-01

    Pepinomozaïekvirus (PepMV) is een virus wat voor het eerst gevonden is in bladmonsters genomen in 1974 van pepino planten (Solanum muricatum) in de Canete vallei in Peru. Jonge bladeren van deze planten vertoonden wat geel mozaïek. In de elektronenmicroscoop (EM) bleken er in deze planten typische

  11. Monitoring the entry of young people into labour market: the potential of the EU-LFS

    NARCIS (Netherlands)

    Berkhout, P.H.G.; Berkhout, E.E.; Biermans, M.L.; van der Valk, J.

    2006-01-01

    Om beter zicht te krijgen op de toetreding van jonge mensen op de arbeidsmarkt in de EU is er in de 'EU Labour Force Study 2000' een ad hoc module geïntroduceerd. Deze module, 'School-To-Work Transition', staat in 2009 opnieuw gepland. Vooruitlopend hierop is SEO Economisch Onderzoek door Eurostat

  12. Sex and Drugs before Rock 'n' Roll : Youth Culture and Masculinity during Holland's Golden Age

    NARCIS (Netherlands)

    Roberts, Benjamin B.

    2012-01-01

    Dit boek richt zich op één generatie van jonge mannen die werd geboren rond 1600 en volwassen werd tijdens het hoogtepunt van de Gouden Eeuw. Van bekende generatiegenoten, zoals Rembrandt van Rijn, wordt onderzocht hoe ze uiting gaven aan hun jongerencultuur en mannelijkheid. Roberts onderzoekt de

  13. Suikers en zoetstoffen kunnen de smaakaversie tegen alcohol bij jongeren onderdrukken en consumptie bevorderen :

    NARCIS (Netherlands)

    Opperhuizen A; GBO

    2010-01-01

    De zoete smaak van sommige zwak-alcoholhoudende dranken zorgt voor smaakherkenning en waarderingsreacties in de hersenen waardoor de aversie tegen alcohol onderdrukt kan worden.. De smaaksamenstelling van deze dranken verlaagt hierdoor de drempel om sneller en meer alcohol te gaan gebruiken op jonge

  14. Als ze maar van me afblijven : Een onderzoek naar antihomoseksueel geweld in Amsterdam

    NARCIS (Netherlands)

    Buijs, Laurens; Duyvendak, Jan Willem; Hekma, Gert

    2008-01-01

    Geweld tegen homo's is een veelvoorkomend en structureel verschijnsel in Nederlands gay capital. Ondanks de liberale reputatie van Amsterdam zijn vooroordelen over mannelijkheid en (homo)seksualiteit wijdverspreid. Dat leidt, voornamelijk bij jonge mannen, tot het plegen van geweld. Als ze maar van

  15. Elon Musk, een visionaire ondernemer

    NARCIS (Netherlands)

    ir.ing. Ruud Thelosen

    2016-01-01

    Deze biografie van de nog vrij jonge ondernemer en maatschappijvernieuwer Elon Musk is een bijzonder boek over een bijzondere man. Musk beschikt over uitzonderlijke gaven en heeft deze ook sterk ontwikkeld. Daarnaast realiseert hij zijn diepste dromen, die misschien wel leiden tot een Marskolonie.

  16. Astma bij peuters en kleuters: Resultaten van het PIAMA onderzoek

    NARCIS (Netherlands)

    Wijga AH; Brussee JE; Smit HA; PZO

    2004-01-01

    In dit rapport worden resultaten gepresenteerd over het beloop van gediagnosticeerd astma bij kinderen van 0-5 jaar in het PIAMA onderzoek. Specifiek voor deze leeftijdsgroep is het probleem dat astma wel voorkomt, maar medisch niet met zekerheid is vast te stellen. Bij jonge kinderen leiden

  17. A reference model and technical framework for mobile social software for learning

    NARCIS (Netherlands)

    De Jong, Tim; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong,T., Specht, M., & Koper, R. (2008). A reference model and technical framework for mobile social software for learning. In I. A. Sánchez & P. Isaías (Eds.), Proceedings of the IADIS Mobile Learning Conference 2008 (pp. 206-210). April, 11-13, 2008, Carvoeiro, Portugal.

  18. Development of Repeated Sprint Ability in Talented Youth Basketball Players

    NARCIS (Netherlands)

    te Wierike, Sanne C. M.; de Jong, Mark C.; Tromp, Eveline J. Y.; Vuijk, Pieter J.; Lemmink, Koen A. P. M.; Malina, Robert M.; Elferink-Gemser, Marije T.; Visscher, Chris

    te Wierike, SCM, de Jong, MC, Tromp, EJY, Vuijk, PJ, Lemmink, KAPM, Malina, RM, Elferink-Gemser, MT, and Visscher, C. Development of repeated sprint ability in talented youth basketball players. J Strength Cond Res 28(4): 928-934, 2014-Factors affecting repeated sprint ability (RSA) were evaluated

  19. De Ratio van Corporate Governance

    NARCIS (Netherlands)

    A. de Jong (Abe)

    2006-01-01

    textabstractAbe de Jong (1970) is Professor in Corporate Finance and Corporate Governance at RSM Erasmus University. He obtained a PhD in finance at Tilburg University (1999). His research and teaching interests are in the area of empirical corporate finance and include capital structure choice,

  20. Reverse engineering large-scale genetic networks: synthetic versus ...

    Indian Academy of Sciences (India)

    2010-04-19

    Apr 19, 2010 ... process computationally to describe the structure of the sys- tem and ... to the different mathematical formalisms used to model net-. Keywords. gene ..... All the algorithms were implemented in MATLAB 7.0 and run on all the 'gold ..... De Jong H. 2002 Medeling and simulation of genetic regulatory systems: a ...

  1. Does postoperative 'M' technique (R) massage with or without mandarin oil reduce infants' distress after major craniofacial surgery?

    NARCIS (Netherlands)

    de Jong, Marjan; Lucas, Cees; Bredero, Hansje; van Adrichem, Leon; Tibboel, Dick; van Dijk, Monique

    2012-01-01

    de jong m., lucas c., bredero h., van adrichem l., tibboel d. & van dijk m. (2011) Does postoperative M technique (R) massage with or without mandarin oil reduce infants distress after major craniofacial surgery? Journal of Advanced Nursing68(6), 17481757. Abstract Aim. This article is a report of a

  2. Zwangerschapsverlof voor boerinnen en tuindersvrouwen

    NARCIS (Netherlands)

    Blom, U.P.; Hoek, van den J.M.

    1989-01-01

    Onderzoek in 2 fasen naar de behoefte aan en de mogelijkheden tot zwangerschaps- en bevallingsverlof bij meewerkende echtgenotes in de agrarische sector: in de 1e fase zijn via een schriftelijke enquete onder 515 jonge meewerkende echtgenotes gegevens verzameld over de mate van meewerken op het

  3. Die adversatiewe stelsel van bewyslewering en die beste belang ...

    African Journals Online (AJOL)

    MJM Venter

    weeg. Hierdie vraag word teen die agtergrond daarvan beoordeel dat veral dispute ..... restructuring family into the highly polarized positions of court-based dispute resolution.16. Talle alternatiewe om tekortkominge in die adversatiewe proses te ..... De Jong M "Mediation and Other Appropriate Forms of Alternative Dispute.

  4. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. M-H Shih. Articles written in Sadhana. Volume 34 Issue 3 June 2009 pp 421-437. A model for signal processing and predictive control of semi-active structural control system · M-H Shih W-P Sung Ching-Jong Wang · More Details Abstract Fulltext PDF. The theory for structural control has been ...

  5. Dental erosion : the role of acidic beverages, saliva and toothpastes in the development and reduction of dental erosion

    NARCIS (Netherlands)

    Jager, Derk Hendrik Jan

    2012-01-01

    Tanderosie, het oplossen van glazuur en dentine onder invloed van zuren die niet door bacteriën zijn geproduceerd, lijkt een grote rol te spelen in het ontstaan van gebitsslijtage op jonge leeftijd. Het is nog niet volledig bekend hoe tanderosie ontstaat. Daarom was het doel van dit

  6. Cross sectional efficient estimation of stochastic volatility short rate models

    NARCIS (Netherlands)

    Danilov, Dmitri; Mandal, Pranab K.

    2001-01-01

    We consider the problem of estimation of term structure of interest rates. Filtering theory approach is very natural here with the underlying setup being non-linear and non-Gaussian. Earlier works make use of Extended Kalman Filter (EKF). However, as indicated by de Jong (2000), the EKF in this

  7. 14 November 2014 - F. van der Duyn Schouten Rector Magnificus Vrije Universiteit University Amsterdam Kingdom of the Netherlands

    CERN Multimedia

    Guillaume, Jeanneret

    2014-01-01

    signing the Guest Book with ATLAS Collaboration, Dutch senior physicist H. ten Kate and visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler; ATLAS Collaboration, Director of Nikhef as of December 1, 2014 S. Bentvelsen and ATLAS Collaboration, Nikhef P. de Jong.

  8. Tritrichomonas foetus bij de kat

    NARCIS (Netherlands)

    van der Leij, W.J.R.

    Tritrichomonas foetus-infecties bij katten verlopen vaak symptoomloos, maar kunnen ook tot chronische colitis leiden. Klinische klachten worden vooral gevonden bij jonge raskatten. Of dit te maken heeft met de leefomstandigheden van raskatten of met een verhoogde gevoeligheid is niet duidelijk. De

  9. Root and critical point behaviors of certain sums of polynomials

    Indian Academy of Sciences (India)

    Seon-Hong Kim

    2018-04-24

    Apr 24, 2018 ... Root and critical point behaviors of certain sums of polynomials. SEON-HONG KIM1,∗. , SUNG YOON KIM2, TAE HYUNG KIM2 and SANGHEON LEE2. 1Department of Mathematics, Sookmyung Women's University, Seoul 140-742, Korea. 2Gyeonggi Science High School, Suwon 440-800, Korea.

  10. Tubular kidney injury molecule-1 in protein-overload nephropathy

    NARCIS (Netherlands)

    van Timmeren, Mirjan M.; Bakker, Stephan J. L.; Vaidya, Vishal S.; Bailly, Veronique; Schuurs, Theo A.; Damman, Jeffrey; Stegeman, Coen A.; Bonventre, Joseph V.; van Goor, Harry

    Kim-1, a recently discovered membrane protein, is undetectable in normal kidneys but markedly induced in proximal tubules after ischemic and toxic injury. The function of Kim-1 is unclear, but it is implicated in damage/repair processes. The Kim-1 ectodomain is cleaved by metalloproteinases and

  11. 75 FR 69160 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-11-10

    ... Kendall Teresa Kennedy Christin Susan Kim Chung H. Kim Hannah Boyoung Kim Johnny Han Kin Tse Wing Kiresepi... Ronald Lao Man Bee Lao Ruperto C. Laty Fabrice S. Lau Kwok Chu Lau Lawrence Juen-Yee Lau Megan Shirley... Po Polly Tsangrides Philippos Alexandros Tse Anthony Wai Chung Tse Christopher Tung Alan Leih-Sing...

  12. Working Programme 2010. Knowledge Institute for Mobility Policy

    International Nuclear Information System (INIS)

    Jorritsma, P.; Derriks, H.; Francke, J.; Gordijn, H.; Groot, W.; Harms, L.; Van der Loop, H.; Peer, S.; Savelberg, F.; Wouters, P.

    2009-12-01

    The Dutch Knowledge Institute for Mobility Policy (KiM) provides analyses of mobility that influence the policy. As a separate institute within the Ministry of Transport, Public Works and Water management, the KiM conducts strategic outlooks and policy analyses. KiM establishes working programs annually. [nl

  13. Influence of hydrogen on chemical vapour synthesis of different ...

    Indian Academy of Sciences (India)

    Administrator

    The role of hydrogen on the surface passivation behaviour of the Ni catalyst and its ..... Chae S J, Güneş F, Kim K K, Kim E S, Han G H, Kim S M,. Shin H-J, Yoon ... Xiong Y G, Suda Y, Wang D Z, Huang Y J and Ren Z F 2005. Nanotechnology ...

  14. The impact of sugar and fatty acid on the bioactivity of N-fatty acyl-L ...

    Indian Academy of Sciences (India)

    SRIKANTH VUDHGIRI

    complex on colon cancer cells J. Food Biochem. 39. 238. 36. Kim D H, Jung E A, Sohng I S, Han J A, Kim T H and Han M J 1998 Intestinal bacterial metabolism of flavonoids and its relation to some biological activities. Arch. Pharm. Res. 21 17. 37. Kim D H 2002 Herbal medicines are activated by intesti- nal microflora Nat.

  15. Brassia campestris L. ssp. chinensis L.var. utilis Tsen et Lee

    African Journals Online (AJOL)

    omodibo

    2012-12-31

    Dec 31, 2012 ... On the basis of morphological and cultural features, the pathogen ... Alternaria isolate from Purple-Caitai showed 99% identity with other ITS sequences of .... Cho KH, Park SH, Kim KT, Kim S, Kim JS, Park BS, Woo JG, Lee HJ.

  16. Supplementary data: Association of CTLA4, CD28 and ICOS gene ...

    Indian Academy of Sciences (India)

    Supplementary data: Association of CTLA4, CD28 and ICOS gene polymorphisms with clinicopathologic characteristics of childhood IgA nephropathy in Korean population. Hak-Jae Kim, Joo-Ho Chung, Sungwook Kang, Su-Kang Kim, Byoung-Soo Cho, Sung-Do Kim and Won-Ho Hahn. J. Genet. 90, 151–155. Table 1.

  17. Graphene Synthesis and Characterization

    Science.gov (United States)

    2015-04-08

    aplications in devices, because can be properly scaled to industrial level. It was studied the experimental parameters involved in the growth of graphene...Balakrishnan, T. Lei, H. R. Kim, Y. I. Song, Y.-J. Kim, K. S. Kim, B. Özyilmaz, J:-H Ahn, B. H. Hong and S. Iijima, Nature Nanotechnology , 5, 574, 2010. Roll

  18. Ocular manifestations of idiopathic aplastic anemia: retrospective study and literature review

    Directory of Open Access Journals (Sweden)

    Mansour AM

    2014-04-01

    Full Text Available Ahmad M Mansour,1 Jong Wook Lee,2 Seung Ah Yahng,2 Kyu Seop Kim,3 Maha Shahin,4 Nelson Hamerschlak,5 Rubens N Belfort,6 Shree K Kurup71Department of Ophthalmology, American University of Beirut, Rafic Hariri University Hospital, Beirut, Lebanon; 2Division of Hematology, Seoul St Mary’s Hospital, The Catholic University of Korea, Seoul, Republic of Korea; 3Department of Ophthalmology, Seoul St Mary’s Hospital, The Catholic University of Korea, Seoul, Republic of Korea; 4Department of Ophthalmology, Mansoura University, Mansoura City, Egypt; 5Oncology and Hematology Program, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil; 6Vision Institute, Hospital São Paulo, Federal University of São Paulo, Brazil; 7Department of Ophthalmology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USAAbstract: Aplastic anemia (AA is a rare disease with few reports on its ophthalmic ­manifestations. The ocular findings are described in a retrospective consecutive series of 719 AA Korean patients followed at the Hematology Clinic of The Catholic University of Korea. Out of a total of 719 patients, 269 patients had eye examinations, 156 patients had retinal evaluation, and 37 (23.7% had retinal findings. These 37 patients had unilateral retinal ­hemorrhage in seven and bilateral retinal hemorrhage in 30 with mean hemoglobin of 6.6 g/dL (range 2.7–12.6 g/dL and platelet counts of 18.8×109/L (range 4–157×109/L; central retinal vein occlusion-like picture occurred in nine patients and these had similar rheology to the rest of the subjects; optic disc edema, cotton-wool spots, macular edema, and dry eyes occurred in two, three, five, and three patients, respectively. In this Korean series of 141 subjects with AA, systemic bleeding occurred in 24.8% of subjects, retinal hemorrhage in 37% of subjects, and any bleeding site (eye or elsewhere occurred in 47.5% of subjects with AA. A

  19. A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects

    Directory of Open Access Journals (Sweden)

    Park SI

    2015-02-01

    Full Text Available Sang-In Park,1,* Howard Lee,1,2,* Jaeseong Oh,1 Kyoung Soo Lim,3 In-Jin Jang,1 Jeong-Ae Kim,4 Jong Hyuk Jung,4 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Clinical Trials Center, Seoul National University Hospital, Seoul, 3Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine and CHA Bundang Medical Center, Seongnam, 4LG Life Sciences, Ltd, Seoul, Republic of Korea *These authors contributed equally to this work Background: In type 2 diabetes mellitus, fixed-dose combination (FDC can provide the complementary benefits of correction of multiple pathophysiologic defects such as dysfunctions in glycemic or metabolic control while improving compliance compared with separate tablets taken together. The objective of the study reported here was to compare the pharmacodynamic (PD, pharmacokinetic (PK, and tolerability profiles of gemigliptin and extended-release metformin (metformin XR between FDC and separate tablets.Methods: A randomized, open-label, single-dose, two-way, two-period, crossover study was conducted in 28 healthy male volunteers. Two FDC tablets of gemigliptin/metformin 25/500 mg or separate tablets of gemigliptin (50 mg ×1 and metformin XR (500 mg ×2 were orally administered in each period. Serial blood samples were collected up to 48 hours post-dose to determine dipeptidyl peptidase 4 (DPP-4 activity using spectrophotometric assay and concentrations of gemigliptin and metformin using tandem mass spectrometry. Geometric mean ratios (GMRs of FDC to separate tablet formulations and their 90% confidence intervals (CIs were calculated to compare the PD and PK parameters between the two formulations. Tolerability was assessed throughout the study.Results: The plasma DPP-4 activity

  20. Korean Medication Algorithm Project for Bipolar Disorder: third revision

    Directory of Open Access Journals (Sweden)

    Woo YS

    2015-02-01

    Full Text Available Young Sup Woo,1 Jung Goo Lee,2,3 Jong-Hyun Jeong,1 Moon-Doo Kim,4 Inki Sohn,5 Se-Hoon Shim,6 Duk-In Jon,7 Jeong Seok Seo,8 Young-Chul Shin,9 Kyung Joon Min,10 Bo-Hyun Yoon,11 Won-Myong Bahk1 1Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; 2Department of Psychiatry, Inje University Haeundae Paik Hospital, Busan, South Korea;3Paik Institute for Clinical Research, Inje Univeristy, Busan, South Korea; 4Department of Psychiatry, Jeju National University Hospital, Jeju, South Korea; 5Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, South Korea; 6Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University, Cheonan, South Korea; 7Department of Psychiatry, Sacred Heart Hospital, Hallym University, Anyang, South Korea; 8Department of Psychiatry, School of Medicine, Konkuk University, Chungju, South Korea; 9Department of Psychiatry, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, South Korea; 10Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, South Korea; 11Department of Psychiatry, Naju National Hospital, Naju, South Korea Objective: To constitute the third revision of the guidelines for the treatment of bipolar disorder issued by the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP 2014. Methods: A 56-item questionnaire was used to obtain the consensus of experts regarding pharmacological treatment strategies for the various phases of bipolar disorder and for special populations. The review committee included 110 Korean psychiatrists and 38 experts for child and adolescent psychiatry. Of the committee members, 64 general psychiatrists and 23 child and adolescent psychiatrists responded to the survey. Results: The treatment of choice (TOC for euphoric, mixed, and psychotic mania was the combination of a mood stabilizer (MS and an atypical antipsychotic (AAP; the TOC for

  1. Urine Kidney Injury Molecule-1: A Potential Non-invasive Biomarker for Patients with Renal Cell Carcinoma

    Science.gov (United States)

    Zhang, Ping L.; Mashni, Joseph W.; Sabbisetti, Venkata S.; Schworer, Charles M.; Wilson, George D.; Wolforth, Stacy C.; Kernen, Kenneth M.; Seifman, Brian D.; Amin, Mitual B.; Geddes, Timothy J.; Lin, Fan; Bonventre, Joseph V.; Hafron, Jason M.

    2014-01-01

    Objective To evaluate the use of urine KIM-1 as a biomarker for supporting a diagnosis of kidney cancers before operation. Methods A total of 19 patients were enrolled in the study based on preoperative imaging studies. Pre-operative and follow-up (1 month) uKIM-1 levels were measured and normalized with uCr levels and renal tumors were stained for KIM-1 using immunohistochemical techniques. Results The percentage of KIM-1 positive staining RCC cells ranged from 10 to 100% and the staining intensity ranged from 1+ to 3+. Based on the KIM-1 staining, 19 cases were divided into the KIM-1-negative staining group (n =7) and the KIM-1-positive group (n = 12). Serum creatinine (sCR) levels were significantly elevated after nephrectomy in both groups. In the KIM-1 negative group, uKIM-1/uCr remained at a similar level before (0.37 ± 0.1 ng/mg Cr) and after nephrectomy (0.32 ± 0.01 ng/mg Cr). However, in the KIM-1 positive group, elevated uKIM-1/uCr at 1.20 ± 0.31 ng/mg Cr was significantly reduced to 0.36± 0.1 ng/mg Cr, which was similar to the pre-operative uKIM-1/uCr (0.37 ± 0.1 ng/mg Cr) in the KIM-1 negative group. Conclusion Our study showed significant reduction in uKIM-1/uCr after nephrectomy, suggesting that urine KIM-1 may serve as a surrogate biomarker for kidney cancer and a non-invasive pre-operative measure to evaluate the malignant potential of renal masses. PMID:23979814

  2. Synthesis, Transfer, and Characterization of Nanoscale 2-Dimensional Materials

    Science.gov (United States)

    2015-09-01

    Shi Y, Hamsen C, Jia X, Kim KK, Reina A, Hofmann M, Kong J. Synthesis of few-layer hexagonal boron nitride thin film by chemical vapor deposition...hexagonal boron nitride layers. Nano Letters. 2010;10(8):3209–3215. 12. Kim KK, Hsu A, Jia X, Kim SM, Shi Y, Hofmann M, Kong J. Synthesis of...microscopy. Physical Review B. 2009;80(15):155425. 33. Kim KK, Hsu A, Jia X, Kim SM, Shi Y, Hofmann M, Kong J. Synthesis of monolayer hexagonal boron

  3. Nanotechnology in paper electronics

    Science.gov (United States)

    Demming, Anna; Österbacka, Professor Ronald; Han, Jin-Woo, Dr

    2014-03-01

    connections in the nervous system, these synaptic transistors can mimic synaptic stimulation response and short-term synaptic plasticity. The idea of harnessing paper electronics for display applications seems a natural update on the familiar traditional uses of paper to host text and images. Jong-Man Kim and Bora Yoon at Hanyang University in Korea screen print a flexible paper-based display for representing the digits 0-9 [5]. The device exploits the electrochromothermic properties of five different polydiacetylenes to allow a range of activation temperatures and operational voltages for the display. A number of other applications also feature in the special issue, including two different supramolecular recognition architectures for DNA hybridization in sensing applications [6] and all-solid flexible micro-supercapacitors with excellent cycling stability [7]. The demonstrated potential in the alternative energy industry seems particularly fitting given the environmental recommendations of paper electronics. Despite the promising outlook demonstrated for fabricating on paper by screen or ink-jet printing, as Henrik A Andersson and colleagues point out, it may be some time before devices can be printed with the functionality of even the most inexpensive microcontroller or other integrated circuit [8]. In their report they consider different methods to mount and contact standard surface mount device components to ink-jet printed conductive tracks on paper substrates. 'If paper is used as a substrate for printed hybrid electronics, it opens the possibility of integrating low-cost electronic functions directly on packages, even possibly directly in the production line', they add. A blank sheet of paper can be considered useful for making notes, convenient for slipping in a purse or pocket and enormously inspiring for the infinity of ideas not yet written on it. As this special issue demonstrates [2-14] all three attributes are at least as valid when using paper for electronics

  4. Comparison of hydration and nutritional status between young and elderly hemodialysis patients through bioimpedance analysis

    Directory of Open Access Journals (Sweden)

    Lee JE

    2015-08-01

    Full Text Available Jung Eun Lee,1,2 In Young Jo,3 Song Mi Lee,3 Woo Jeong Kim,3 Hoon Young Choi,2,4 Sung Kyu Ha,4 Hyung Jong Kim,5 Hyeong Cheon Park2,4 1Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, 2Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, 3Department of Nutrition Services, Gangnam Severance Hospital, 4Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 5Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea Background: The number of elderly people on dialysis is increasing rapidly. Fluid overload and malnutrition status are serious problems in elderly dialysis patients. We aimed to compare the hydration and nutritional status through bioimpedance analysis (BIA between young and elderly hemodialysis (HD patients and to analyze risk factors related to fluid overload and malnutrition status in these patients.Method: We conducted a cross-sectional study, in which 82 HD (males 42, mean age 58.7±12.9 years patients were enrolled. We collected different types of data: laboratory data, such as serum creatinine, albumin, total iron-binding capacity, hemoglobin, total cholesterol; anthropometric data, such as hand grip strength (HGS; BIA data, such as intracellular water, skeletal muscle mass, body cell mass, bone mineral content, phase angle (PhA, extra cellular water (ECW/total body water (TBW ratio; and malnutrition-inflammation score (MIS, which is a traditional nutritional parameter for dialysis patients. All patients were stratified into two groups according to their age: young (<65 years [n=54] and elderly (≥65 years [n=28].Results: Total iron-binding capacity and HGS were significantly lower in elderly HD patients than in young HD patients (198.9±35.6 vs 221.4±52.1 mcg/dL; and 22.4±10.3 vs 36.4±23.2 kg, respectively (P<0.05. Also, intracellular water and Ph

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Willem Ysbrantsz. Bontekoe

    1958-10-01

    Full Text Available - P.E. de Josselin de Jong, Kaj Birket-Smith, An ethnological sketch of Rennell Island: a Polynesian outlier in Melanesia. Dan. Hist. Filol. Medd. 35, no. 3 (1956. 207 p. - P.E. de Josselin de Jong, B. Schrieke, Selected writings of...Indonesian sociological studies. Part Two: Ruler and realm in early Java. W. van Hoeve Ltd., The Hague & Bandung 1957, 309 p., notes, bibl. - P. van Emst, J.W. Schoorl, Kultuur en kultuurveranderingen in het Moejoe-Gebied. Diss. Leiden 1957. Handelsuitgave bij J.N. Voorhoeve, Den Haag 1957, 298 pp. - W. Ph. Coolhaas, Willem Ysbrantsz. Bontekoe, Journaal van Willem Ysbrantsz. Bontekoe, uitgegeven naar de oorspronkelijke tekst met woordverklaringen door Clara Eggink; Tjeenk Willink, Haarlem, 1957, 159 p. - L.F. Fitzhardinge, M. Clark, Sources of Australian history, selected and edited by M. Clark. London, Oxford University Press, 1957.

  6. Plant virus directed fabrication of nanoscale materials and devices

    Science.gov (United States)

    2015-03-26

    Structural features within the internal and external PVN surfaces are amenable to either chemi- cal or genetic modifications for the display of novel moieties...structures: from nanoboomerangs to tetrapods. Nanoscale 7, 344–355. Eggen, R., Verver, J., Wellink, J., De Jong, A., Goldbach, R., van Kammen, A., 1989...in planta expression and for templates for synthetic biology applica- tions. New Phytol. 200, 16–26. Saunders, K., Sainsbury, F., Lomonossoff, G.P

  7. De Geologie van het Val Brembo di Foppolo en de Valle di Carisole

    NARCIS (Netherlands)

    Wennekers, J.H.L.

    1928-01-01

    Le terrain exploré fait partie du prolongement vers l’est de la zone des Alpes bergamasques que Cosijn et Jong ont commencé à mettre en carte en 1926 (fig. 1). Il comprend des parties du cristallin situé au nord de la „ligne orobique”, du paquet d’écaillés (série porphyrique, série Collio,

  8. Multiple Kernel Learning for Explosive Hazard Detection in Forward-Looking Ground-Penetrating Radar

    Science.gov (United States)

    2012-04-01

    Kevin Stone, Derek T. Anderson, James M. Keller, Dominic K.C. Ho, Tuan T. Ton, David C. Wong , Mehrdad Soumekh University of Missouri - Columbia...James M. Kellera, K.C. Hoa, Tuan T. Tone, David C. Wong\\ and Mehrdad Soumekhd aDept. ofElectrical and Computer Engineering, University of Missouri...2] Cremer , F., Schavemaker, J.G., de Jong, W., and Schutte, K., "Comparison of vehicle-mounted forward-looking polarimetric infrared and downward

  9. Narrow-Band Processing and Fusion Approach for Explosive Hazard Detection in FLGPR

    Science.gov (United States)

    2011-01-01

    Keller, K. C. Ho, Tuan T. Ton, David C. Wong, Mehrdad Soumekh University of Missouri - Columbia Office of Sponsored Programs The Curators of the...Timothy C. Havens* a , James M. Keller a , K.C. Ho a , Tuan T. Ton b , David C. Wong b , and Mehrdad Soumekh c a Dept. of Electrical and Computer...ARO. REFERENCES [1] Cremer , F., Schavemaker, J.G., de Jong, W., and Schutte, K., "Comparison of vehicle-mounted forward-looking polarimetric

  10. Improved Detection and False Alarm Rejection Using FLGPR and Color Imagery in a Forward-Looking System

    Science.gov (United States)

    2010-01-01

    W911NF-05-1-0069 Havens, Tim, C. Spain, Christopher, J. Ho, Dominic, K.C. Keller, James, M. Ton, Tuan, T. Wong, David , C. Soumekh, Mehrdad...James M. Kellera, Tuan T. Tonb, David C. Wong, and Mehrdad Soumekhc aDept. of Electrical and Computer Engineering, University of Missouri...Research Office (48343-EV) in support of the u.s. Army RDECOM CERDEC NVESD. REFERENCES [1] Cremer , F., Schavemaker, J.G., de Jong, W., and Schutte, K

  11. Fulltext PDF

    Indian Academy of Sciences (India)

    E K, Guan R, Magnone S R, Johnson E F, Bouska J J,. Olson A M, Jong R D, Oltersdorf T, Luo Y, Rosenberg. S H, Girandaa V L and Li Q 2006 Bioorg. Med. Chem. 14 6832. 9. D'Amour F E and Smith D L 1941 J. Pharmacol. Exp. Ther. 72 74. 10. Winter C A, Risley E A and Nuss G W 1962 Proc. Soc. Exp. Biol. Med. 111 544.

  12. NRH Neuroscience Research Center

    Science.gov (United States)

    2008-06-01

    Subacute Rehabilitation Programs for Medicare Beneficiiaries with Hip Fracture .: Medical Care. 43 (September) No. 9, 892-901. • DeJong, Gebern (2005...and Costs after Hip Fracture and Stroke: A Comparison of Rehabilitation Settings. JAMA (1997); 277(5): 396-404. 4 Heinemann AW, Hamilton B...back as 1936.32 Hospital associated malnutrition was reported in the middle and late 1970’s.33 34 Early enteral feeding in trauma patients has

  13. ONR Tokyo Scientific Bulletin. Volume 5, Number 1, January-March 1980,

    Science.gov (United States)

    1980-03-01

    postage stamps and a children’s poster contest, for which SCOPE provided prize money. SCOPE is now organizing a seminar on ecotoxicological problems in...the southwest coast is near the most important site for aquaculture. 4. Studies of the pollution of the shellfish cultivation areas of the west coast. 5... Ecotoxicological Problems in the Taipei, Taiwan Dr. Jong-Chin Su, Institute of Zoology lndoPacific Region Academia Sinica, Taipei 115 April 13-17 International

  14. The Balancer Policy Reviewed from the Perspective of the ROK-U.S. Alliance: Toward a Mature ROK-U.S. Alliance

    Science.gov (United States)

    2006-12-01

    one of Korea’s ancient three kingdoms, existed for 700 years ruled by 26 wise kings ) in the papers of the Northeast Project, a government-funded...Relations,” in Korea-U.S. Relations in Transition, ed. Baek Jong-chun and Lee Sang-hyun (Sungnam: Sejong Institute, 2002). 51 military alliance it was...President, President’s Roh’s Inauguration Announcement, Vol. 1, Secretary Office, 2003. 62 Sejong Laboratory, National strategy for 21st century

  15. Enhanced Densification of White Cast Iron Powders by Cyclic Phase Transformations under Stress.

    Science.gov (United States)

    1981-08-01

    Little or no significant enhancement in densification was reported in these cases where no applied stresses were used. Kohara [9) extended this work...enhancement of densification observed by Kohara , although limited, was attributed to the occurrence of transformation superplasticity. As will be shown... Kohara : Metall. Trans., 1976, vol. 7, p. 1239. 10. Y. Oshida, J. Jpn. Soc, Powder and Powder Metall., 1975, vol. 22, p. 147. 11. M. de Jong and G. W

  16. From Rowing Between Two Reefs to Sailing in Two Oceans: The End of A Thousand Friends, Zero Enemies

    Science.gov (United States)

    2015-12-01

    Post, February 4, 2015, http://www.thejakartapost.com/news/2015/02/04/susi-best-performing-minister-lsi.html and Hans Nicholas Jong, “Survey Suggests...relations. The prime drivers of Indonesia’s foreign policy, as Paige Johnson Tan assesses, are contextualized to the country’s domestic politics...political and economic conditions, and sometimes even natural disasters, provide a practical limit on Indonesia’s aspirations.102 Tan gives the example

  17. A case report of suicidal behavior related to subclinical hyperthyroidism

    OpenAIRE

    Jeong, Jong-Hyun; Joo,Soo-Hyun; Hong,Seung-Chul

    2014-01-01

    Soo-Hyun Joo, Jong-Hyun Jeong, Seung-Chul HongDepartment of Psychiatry, St Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, KoreaAbstract: Abnormalities in thyroid function are associated with many psychiatric symptoms. We present a report of a 15-year-old girl who was admitted to the psychiatry inpatient unit with symptoms of suicidal behavior, irritability, and impulsivity. One year previously, she had become more short-tempered, and had started to c...

  18. An Assessment of Media Coverage of the B-2 Stealth Bomber

    Science.gov (United States)

    1990-01-01

    15 Sharon M. Friedman, Carole M. Gorney, and Brenda P. Egolf, "Reporting on Radiation: A Content Analysis of Chernobyl Coverage," Journal of...Mitterrand," Political Science Quarterly, 39 (1987): 103-122. 1 29 Jane Blankenship, Serefa Mendez - Mendez , Jong Guen King and Joseph Giodan, "Initial... Carole M. Gorney and Brenda P. Egolf, "Reporting on Radiation: A Content Analysis of Chernobyl Coverage," Journal of Communication, Summer3 (1987

  19. Die opleiding van bedryfsielkundiges aan die universiteit van Fort Hare

    Directory of Open Access Journals (Sweden)

    W. Botha

    1977-11-01

    Full Text Available Die Departement Bedryfsielkunde aan die Universiteit van Fort Hare is 'n relatiewe jong departement en het eers in 1965 tot stand gekom. Voor hierdie datum is Bedryfsielkunde as 'n kort kursus deur die departement van suiwer Sielkunde aangebied en een van die destydse dosente, Dr. W. Backer, het die inisiatief geneem om 'n selfstandige departement van Bedryfsielkunde in die Fakulteit van Ekonomiese Wetenskappe op die been te bring.

  20. Seasonal variations in the vertical distribution of benthic microalgae in the upper sediment of the Mdloti Estuary, South Africa

    CSIR Research Space (South Africa)

    Mundree, S

    2003-01-01

    Full Text Available on the surrounding sedimentary envi- ronment (Lucas et al. 2000). Hence, cycles of re-sus- pension, deposition and burial of microphytobenthos are caused primarily by turbulent water currents and further influenced by sediment properties or cohe- siveness (Mehta 1988...), wave action, storm events (Demers et al. 1987, de Jonge and van Beusekom 1992, 1995) and bioturbation or biostabilisation by benthic animals (Grant and Daborn 1994, Miller et al. 1996). Furthermore, small-scale characteristics of the sedimentary...

  1. Ervaren stressoren bij Peruviaanse universiteitsstudenten

    OpenAIRE

    Van den Broucke, Stephan; Chau, Cecilia

    2011-01-01

    Achtergrond: Omgaan met de ontwikkelingstaken van de adolescentie kan leiden tot psychische druk. Ofschoon de specifieke stressoren die jonge mensen ervaren sterk afhankelijk zijn van de culturele context waarin zij opgroeien, is er maar weinig onderzoek verricht naar de stress en naar de manieren om ermee om te gaan bij jongeren in landen buiten Noord-Amerika of Europa. Doelstelling: Nagaan van ervaren stressoren en coping- mechanismen bij Peruviaanse universiteitstudenten. Meth...

  2. The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women

    Directory of Open Access Journals (Sweden)

    N V Mazurina

    2013-03-01

    Full Text Available Реферат по материалам статьи The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women. Park HТ, Lee ES, Cheon EP, Lee DR, Yang K-S, Kim YT, Hur JY, Kim SH, Lee KW, Kim T. Clinical Endocrinology 2012; 76, 59-66.

  3. Pop / Raul Saaremets

    Index Scriptorium Estoniae

    Saaremets, Raul

    2002-01-01

    Heliplaatidest Starsailor" Love is Here". Chicago Underground Quartet "Chicago Underground Quartet". Mower "Mower". Kim Wilde "The Very Best of". Mull Historical Society "Loss". Jill Scott "Experience: 826+"

  4. Assessment of the Genetic Variation in Bone Fracture Healing

    Science.gov (United States)

    2004-10-01

    9 A ppendices ............................................................................................. 10 3...injuries as well as acute trauma (Kim, 2003; Pittet et al., 2002). 6 Figure 1. Transverse (upper) and sagittal (lower) images obtained using

  5. First results from RHIC-PHENIX£

    Indian Academy of Sciences (India)

    S C Johnson,. Ѕѕ. K S Joo, ѕї. S Kametani,. ½. J H Kang,. ¿. M Kann, їј. S S Kapoor,. ¾. S Kelly, B Khachaturov,. ¾. A Khanzadeev, їј. J Kikuchi,. ½. D J Kim,. ¿. H J Kim,. ¿. S Y Kim,. ¿. Y G Kim,. ¿. W W Kinnison,. ½. E Kistenev,. ¿. A Kiyomichi,. ¿. C Klein-Boesing, ѕѕ. S Klinksiek,. ¾. L Kochenda, їј. D Kochetkov, V Kochetkov,.

  6. Joint Services Electronics Program. Electronics Research at the University of Texas at Austin.

    Science.gov (United States)

    1986-09-30

    White, Physics Kyoung II Kim , ECE John White, Aerospace Tae Sung Kim , ECE Murray Wolinsky, Physics Taiho Koh, ECE * L.A. Wu, Physics Tom Koonce...on Acutc.SpehadSignal Processing, Vol. 1, March 1984, San Diego, California, pp. - ’ -’.,"" 27. Kyoung 11 Kim and Edward J. Powers, "Digital Estimation...Craig Farley, ECE, M.S., May 1985, "The Migration and Activation of Impurities in Ion- Implanted Semiconductors." Dae Yong Kim , ECE, M.S., May 1985

  7. Urban / Heidi Purga

    Index Scriptorium Estoniae

    Purga, Heidy, 1975-

    2005-01-01

    Uutest heliplaatidest Earth, Wind & Fire "Illumination", Kanye West "Late Registration", Stereo MC's "Paradise", Shaggy "Clothes Drop", Lil Kim "The Naked Truth", Babyface "Grown and Sexy", Sean Paul "Trinity"

  8. Characteristics of porous zirconia coated with hydroxyapatite as ...

    Indian Academy of Sciences (India)

    TECS

    Zirconia; porosity; hydroxyapatite; coating; compressive strength. 1. Introduction. A lot of .... typically from 300–500 μm, estimated from the SEM images. Thus, the .... Kim H W, Georgiou F, Knowles J C, Koh Y H and Kim H E. 2004 Biomaterials ...

  9. Compassion and Curiosity - TCGA

    Science.gov (United States)

    William Kim, M.D., is motivated by two things: compassion and curiosity. Dr. Kim has taken these dual motivations and created a career in which he cares directly for patients and spearheads research that may lead to improved treatment options.

  10. Determination of antidepressant activity of Cyperus rotundus L ...

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research April 2017; 16 (4): 867-871 ... 1Shandong University School of Medicine, Jinan, 250012, 2Department of Psychology, People's Hospital of Linyi City, Linyi,. 276003 ..... Academic Press, 1977: 692-698. 8. Porsolt RD, Bertin A ... Lim DW, Jung JW, Park JH, Baek NI, Kim YT, Kim IH,.

  11. Studies on dehydrogenation of cyclohexanol to cyclohexanone over ...

    Indian Academy of Sciences (India)

    B SRIDEVI

    cGovernment College for Women, Osmania University, Koti, Hyderabad, ... MS received 12 September 2016; revised 22 February 2017; accepted 28 ..... Burri D R, Jun K W, Kim Y H, Kim J M, Park S E .... troscopy (New York: Plenum Press).

  12. Kidney injury molecule-1 in renal disease

    NARCIS (Netherlands)

    Waanders, Femke; van Timmeren, Mirjan M.; Stegeman, Coen A.; Bakker, Stephan J. L.; van Goor, Harry

    Kidney injury molecule-1 (KIM-1) is a marker for renal proximal tubular damage, the hallmark of virtually all proteinuric, toxic and ischaemic kidney diseases. KIM-1 has gained increasing interest because of its possible pathophysiological role in modulating tubular damage and repair. In this

  13. Effect of Renin-Angiotensin-Aidosterone System Inhibition, Dietary Sodium Restriction, and/or Diuretics on Urinary Kidney Injury Molecule 1 Excretion in Nondiabetic Proteinuric Kidney Disease : A Post Hoc Analysis of a Randomized Controlled Trial

    NARCIS (Netherlands)

    Waanders, Femke; Vaidya, Vishal S.; van Goor, Harry; Leuvenink, Henri; Damman, Kevin; Hamming, Inge; Bonventre, Joseph V.; Vogt, Liffert; Navis, Gerjan

    Background: Tubulointerstitial damage plays an important role in chronic kidney disease (CKD) with proteinuria. Urinary kidney injury molecule 1 (KIM-1) reflects tubular KIM-1 and is considered a sensitive biomarker for early tubular damage. We hypothesized that a decrease in proteinuria by using

  14. Emissive lead(II) benzenedicarboxylate metal-organic frameworks

    Indian Academy of Sciences (India)

    Abdul Malik P Peedikakkal

    2018-04-16

    Apr 16, 2018 ... Jang E, Jun S, Jang H, Lim J, Kim B and Kim Y 2010. White-light-emitting ... 2837; (b) Li Y-F, Wang D, Liao Z, Kang Y, Ding. W-H, Zheng X-J, Jin L-P 2016 .... Zuo J-L and Zhou H-C 2007 Synthesis and Characteri- zations of a ...

  15. Hydrophilic Cucurbit[7]uril-Pseudorotaxane-Anchored-Monolayer-Protected Gold Nanorods

    Science.gov (United States)

    2013-03-20

    FULL PAPER DOI:10.1002/ejic.201300010 Hydrophilic Cucurbit[7]uril-Pseudorotaxane-Anchored- Monolayer-Protected Gold Nanorods Xiang Ma,[a] Yuhua Xue... Cao , Q. Wang, H. Tian, Chem. Commun. 2011, 47, 3559–3561. [8] a) I. Hwang, K. Baek, M. Jung, Y. Kim, K. M. Park, D. W. Lee, N. Selvapalam, K. Kim, J. Am

  16. Chemical Composition and Anti-Biofilm Activity of Burdock (Arctium ...

    African Journals Online (AJOL)

    formation for cultures treated with burdock leaf fraction, thus confirming the inhibitory efficiency of .... subjected three times to 1 min of sonication ..... 15. Lee K-H, Kim B-S, KeumK-S, Yu H-H, Kim Y-H. Essential. Oil of Curcuma longa Inhibits ...

  17. Bifunctional xylanases and their potential use in biotechnology

    Digital Repository Service at National Institute of Oceanography (India)

    Khandeparker, R.; Numan, M.Th.

    . J Chromatography 919:389–394 33. Hong SY, Lee JS, Cho KM, Math RK, Kim YH, Hong SJ, Cho YU, Kim H, Yun HD (2006) Assembling a novel bifunctional cel- lulase–xylanase from Thermotoga maritima by end-to-end fusion. Biotechnol Lett 28:1857–1862 34...

  18. Efficacy of sodium bicarbonate as anaesthetic for yellow seahorse, Hippocampus kuda (Bleeker, 1852)

    Digital Repository Service at National Institute of Oceanography (India)

    Pawar, H.B.; Ingole, B.S.; Sreepada, R.A.

    .J., Ryu, B.M., Kim, M.M., Kim, S.K., 2008. Free Radical and Reactive Oxygen Species Scavenging Activities of the Extracts from Seahorse, Hippocampus kuda, Bleeler. Biotechnol. Bioprocess Eng. 13, 705- 715. 20. Ross, L.G., Ross, B., 1999. Anaesthetic...

  19. Frames and extension problems I

    DEFF Research Database (Denmark)

    Christensen, Ole

    2014-01-01

    In this article we present a short survey of frame theory in Hilbert spaces. We discuss Gabor frames and wavelet frames and set the stage for a discussion of various extension principles; this will be presented in the article Frames and extension problems II (joint with H.O. Kim and R.Y. Kim)....

  20. Gene expression profiles in adenosine-treated human mast cells ...

    African Journals Online (AJOL)

    Gene expression profiles in adenosine-treated human mast cells. ... SW Kang, JE Jeong, CH Kim, SH Choi, SH Chae, SA Jun, HJ Cha, JH Kim, YM Lee, YS ... beta 4, ring finger protein, high-mobility group, calmodulin 2, RAN binding protein, ...

  1. Gender-divergent expression of lipid and bile acid metabolism ...

    Indian Academy of Sciences (India)

    Yuji Tanaka

    2018-04-10

    Apr 10, 2018 ... mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A. J. Nutr. ... Pozo Rosado P and. Garcıa López D 2011 Positive effects of physical exercise on ... Diabetes 59 1899–1905. Kim J, Kim J and Kwon ...

  2. Synthesis of Nitrogen-doped Carbon Nanotubes with Layered ...

    African Journals Online (AJOL)

    NICO

    Nitrogen-doped carbon nanotubes (CNx) were synthesized by the catalytic chemical vapour deposition ... dispersed metal nanoparticles over oxide matrices can be obtained ..... 18 S.Y. Kim, J. Lee, C.W. Na, J. Park, K. Seo and B. Kim, Chem.

  3. Institutional Change through Assessment: Contrasting Case Studies

    Science.gov (United States)

    Deess, E. Pierre; Elliot, Norbert

    2009-01-01

    The framework for understanding the management difference is neatly captured by the "red ocean" and "blue ocean" strategies described by W. Chan Kim and Renee Mauborgne in "Blue Ocean Strategy" (Kim & Mauborgne, 2004). In the original, the terms refer to alternative market strategies. Red ocean means competition in a market defined by a zero sum…

  4. Analysis of the early response to chemotherapy in lung cancer using ...

    African Journals Online (AJOL)

    Histogram analysis based on the whole-tumor ROI method is preferred for .... displayed on the y-axis. The histogram ... Wang H, Fei B. Diffusion-weighted MRI for monitoring ... Ahn SJ, Choi SH, Kim YJ, Kim KG, Sohn CH, Han MH,. Chang KH ...

  5. Pt-Pd nanoelectrocatalyst of ultralow Pt content for the oxidation of ...

    Indian Academy of Sciences (India)

    formic acid oxidation on Pt4Pd96 nanoparticles. Keywords. ..... Choi J H, Jeong K J, Dong Y, Han J, Lim T H, Lee J S ... Rhee C K, Kim B J, Ham C, Kim Y J, Song K and Kwon ... Wang R, Liao S and Ji S 2008 J. Power Sources 180 205. 18.

  6. Symplocaceae

    African Journals Online (AJOL)

    There are only few reports on the chemical composition of ... However, literature searches have shown no report on ..... Jiang J, Feng Z, Wang Y, Zhang P. New phenolics from the roots of ... Song J, Li N, Xia Y, Gao Z, Zou SF, Kong L, Yao YJ, Jiao. YN, Yan YH ... Han YH, Kee JY, Park J, Kim HL, Jeong MY, Kim DS,. Jeon YD ...

  7. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 112; Issue 2. Sums of Two Polynomials with Each having Real Zeros Symmetric with the Other. Seon-Hong Kim. Volume 112 Issue 2 ... Author Affiliations. Seon-Hong Kim1. School of Mathematical Sciences, Seoul National University, Seoul 151-742, Korea ...

  8. Effects of glycyrrhizin pre-treatment on transient ischemic brain ...

    African Journals Online (AJOL)

    Effects of glycyrrhizin pre-treatment on transient ischemic brain injury in mice. ... on transient ischemic brain injury in mice. Chiyeon Lim, Sehyun Lim, Young-Jun Lee, Bokcheul Kong, Byoungho Lee, Chang-Hyun Kim, Buyeo Kim, Suin Cho ... induced brain damage. Keywords: Glycyrrhizin, licorice, stroke, apoptosis ...

  9. Barrier Engineered Quantum Dot Infrared Photodetectors

    Science.gov (United States)

    2015-06-01

    251108. 6. Barve, Ajit V., Saumya Sengupta, Jun Oh Kim, John Montoya , Brianna Klein, Mohammad Ali Shirazi, Marziyeh Zamiri et al., "Barrier selection... H . Kim, Z-B. Tian, and Sanjay Krishna. "Barrier Engineered Infrared Photodetectors Based on Type-II InAs/GaSb Strained Layer Superlattices." (2013

  10. Assessment of Mindfulness with the French Version of the Kentucky Inventory of Mindfulness Skills in Community and Borderline Personality Disorder Samples

    Science.gov (United States)

    Nicastro, Rosetta; Jermann, Francoise; Bondolfi, Guido; McQuillan, Annabel

    2010-01-01

    This article explores mindfulness skills in community and borderline personality disorder (BPD) samples. Study 1 includes 173 community volunteers and explores the psychometric properties of the French version of the Kentucky Inventory of Mindfulness Skills (KIMS). Study 2 explores the KIMS factor structure in 130 BPD patients and compares KIMS…

  11. African Journal of Biotechnology - Vol 11, No 48 (2012)

    African Journals Online (AJOL)

    ... brain aromatase-induction of monosodium glutamate in estrogen-responsive mosaic transgenic zebra fish Danio rerio · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Tamer Said Abdelkader, Chang Seo-Na, Kim Tae-Hyun, Song Juha, Kim Dongso, Jae-Hak Park ...

  12. We Are Going to Have to Imagine Our Way Out of This One...

    DEFF Research Database (Denmark)

    De Cock, Christian

    2018-01-01

    Book reviews of: New York 2140. Kim Stanley Robinson. London: Orbit, 2017. 624 pp. £20 (hbk). ISBN 9780356508757 Science in the Capital trilogy: Forty Signs of Rain (2004 – ASIN: B01KTJYB5G), Fifty Degrees Below (2005 – ASIN: B00BS06T88), Sixty Days & Counting (2007 – ASIN: B00BS06T8I) – Kim...

  13. High frequency plant regeneration from mature seed- derived callus ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-15

    Dec 15, 2009 ... Ki-Won Lee, Gi Jun Choi, Ki-Yong Kim, Hee Chung Ji, Hyung Soo Park, Sei Hyung Yoon and ... Gramineae family plants (Ha et al., 2001; Dong and Qu, ..... Lee SH, Ahsan N, Lee KW, Kim DH, Lee DG, Kwak SS, Kwon SY, ...

  14. Effect of aging on copper nanoparticles synthesized by pulsed laser ...

    Indian Academy of Sciences (India)

    Administrator

    2009-06-23

    Jun 23, 2009 ... Hsieh C T, Chen J M, Lin H H and Shih H C 2003 Appl. Phys. Lett. 83 3383. Hsieh J H, Kuo P W, Peng K C, Liu S J, Hsueh J D and Chang. S C 2008 Thin ... Jung J H, Kim T W, Song M S, Kim Y H and Yoo K H 2007. J. Appl.

  15. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (81st, Baltimore, Maryland, August 5-8, 1998). Advertising.

    Science.gov (United States)

    Association for Education in Journalism and Mass Communication.

    The Advertising section of the Proceedings contains the following 18 papers: "The Birth of Adwatches: Political Advertising Becomes Front-Page News" (Jennifer Greer); "A Cross-Cultural Comparison of the Effects of Source Credibility on Attitudes and Behavioral Intentions" (Kak Yoon, Choong Hyun Kim, and Min-Sun Kim);…

  16. Strain-Induced Pseudo-Magnetic Fields Greater Than 300 Tesla in Graphene Nanobubbles

    Science.gov (United States)

    2010-07-30

    H. L. Stormer , P. Kim, Nature 438, 201 (2005). 8. K. S. Novoselov et al., Nature 438, 197 (2005). 9. K. I. Bolotin, F. Ghahari, M. D. Shulman, H. L... Stormer , P. Kim, Nature 462, 196 (2009). 10. X. Du, I. Skachko, F. Duerr, A. Luican, E. Y. Andrei, Nature 462, 192 (2009). 11. V. M. Pereira, A. H

  17. Electronic Struture and Quantum Effects of Thin Metal Film Systems Based on Silicon Carbide

    Science.gov (United States)

    2013-05-01

    324, 924 (2009). [33] K. S. Novoselov et al., Nature (London) 438, 197 (2005). [34] Y. Zhang, Y.-W. Tan, H. L. Stormer , and P. Kim, Nature (London...Zhang, Y.-W. Tan, H. L. Stormer , and P. Kim, Nature (London) 438, 201 (2005). [6] K. S. Novoselov et al., Nature Phys. 2, 177 (2006). [7] E. McCann and V

  18. Electron Transport in Graphene From a Diffusion-Drift Perspective

    Science.gov (United States)

    2010-02-24

    Tung, M.E. Schwartz, M. Takita, Y.-J. Wang, P. Kim, and H.L. Stormer , “Cyclotron resonance in bilayer graphene,” Phys. Rev. Lett. 100, 087403 (2008...Dec. 2004. [3] K. I. Bolotin, K. J. Sikes, Z. Jiang, M. Klima, G. Fudenberg, J. Hone, P. Kim, and H. L. Stormer , “Ultrahigh electron mobility in

  19. Snapshots from a leading eco-city

    DEFF Research Database (Denmark)

    Mehlsen, Camilla

    2009-01-01

    The government of Singapore wants to make Singapore the leading Eco-city in Asia. Professor Kim Chuan Goh explains why this might be an achievable goal.......The government of Singapore wants to make Singapore the leading Eco-city in Asia. Professor Kim Chuan Goh explains why this might be an achievable goal....

  20. Gas sensing application of nanocrystalline zinc oxide thin films ...

    Indian Academy of Sciences (India)

    ZnO is a material with a variety of potential applications such as electronics,7 photonics,8 acoustics,9 TCO layer in ..... change, as a response to surface chemical reactions with environmental gases. ..... Wang D, Chu X and Gong M 2007 Nanotechnology 18 185601. 79. Kim K M, Hyun-Mook Jeong, Hae-Ryong Kim, Kwon-Il ...

  1. Different impacts of respiratory symptoms and comorbidities on COPD-specific health-related quality of life by COPD severity

    Directory of Open Access Journals (Sweden)

    Lee H

    2017-11-01

    Full Text Available Hyun Lee,1,* Byung Woo Jhun,1,* Juhee Cho,2–4 Kwang Ha Yoo,5 Jin Hwa Lee,6 Deog Kyeom Kim,7 Jong Deog Lee,8 Ki-Suck Jung,9 Jung Yeon Lee,10 Hye Yun Park1 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; 2Center for Clinical Epidemiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; 3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 4Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, South Korea; 5Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, South Korea; 6Division of Pulmonary and Critical Care Medicine, School of Medicine, Ewha Womans University, Seoul, South Korea; 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea; 8Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University Hospital, Jinju, South Korea; 9Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, South Korea; 10Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungju Hospital, Konkuk University School of Medicine, Chungju, South Korea *These authors contributed equally to this work Background: Patients with chronic obstructive pulmonary disease (COPD often have poor health-related quality of life (HRQoL that is disproportionate to their degree of airflow limitation. This study evaluated the association between St

  2. TESTING SOME PEDO-TRANSFER FUNCTIONS (PTFS IN APULIA REGION

    Directory of Open Access Journals (Sweden)

    Floriano Buccigrossi

    2009-03-01

    Full Text Available The knowledge of soil water retention vs. soil water matric potential is used to study irrigation and drainage schedules, soil water storage capacity (plant available water, solute movement, plant growth and water stress. The hydraulic soil properties measuring is expensive, laborious and takes too long time, so, frequently, matemathic models, called pedo-transfer functions (PTFs are utilized to estimate hydraulic soil properties through soil chimical and phisical characteristics. Six pedo-transfer functions have been evaluated (Gupta & Larson, 1979; Rawls et al., 1982; De Jong et al., 1983; Rawls & Brakensiek, 1985; Saxton et al., 1986; Vereecken et al., 1989 by comparing estimated with measured soil moisture values at soil water matric potential of –33 and –1500 kPa of 361 soil samples collected from 185 pedons of Apulia Region (South Italy, having various combinations of particle-size distribution, soil organic matter content and bulk density. Accuracy of the soil moisture predictions have been evaluated by statistic indexes such as Weighted stantard error (WSEE, Mean Deviation (MD, Root Mean Squared Deviation (RMSD and the determination coefficient (R2 between estimated and measured water retention values. The Rawls PTF model demostrated to have the lowest values of WSEE, MD and RMSD indexes (0.044, -0.007 and 0.059 m3 H2O m-3 soil, respectively at –33 Kpa soil water matric potential (Field Capacity, while for estimating soil moisture at the Wilting Point (-1500 kPa Rawls & Brakensiek model is adequate (WSEE, MD and RMSD of 0.034, -0.016 and 0.046 m3 H2O m-3 soil. De Jong, Saxton and Rawls & Brakensiek models, at –33 kPa soil water matric potential and Gupta & Larson and De Jong models at –1500 kPa soil water matric potential, showed the highest statistic errors.

  3. Kilovoltage Intrafraction Monitoring for Prostate Intensity Modulated Arc Therapy: First Clinical Results

    International Nuclear Information System (INIS)

    Ng, Jin Aun; Booth, Jeremy T.; Poulsen, Per R.; Fledelius, Walther; Worm, Esben Schjødt; Eade, Thomas; Hegi, Fiona; Kneebone, Andrew; Kuncic, Zdenka; Keall, Paul J.

    2012-01-01

    Purpose: Most linear accelerators purchased today are equipped with a gantry-mounted kilovoltage X-ray imager which is typically used for patient imaging prior to therapy. A novel application of the X-ray system is kilovoltage intrafraction monitoring (KIM), in which the 3-dimensional (3D) tumor position is determined during treatment. In this paper, we report on the first use of KIM in a prospective clinical study of prostate cancer patients undergoing intensity modulated arc therapy (IMAT). Methods and Materials: Ten prostate cancer patients with implanted fiducial markers undergoing conventionally fractionated IMAT (RapidArc) were enrolled in an ethics-approved study of KIM. KIM involves acquiring kV images as the gantry rotates around the patient during treatment. Post-treatment, markers in these images were segmented to obtain 2D positions. From the 2D positions, a maximum likelihood estimation of a probability density function was used to obtain 3D prostate trajectories. The trajectories were analyzed to determine the motion type and the percentage of time the prostate was displaced ≥3, 5, 7, and 10 mm. Independent verification of KIM positional accuracy was performed using kV/MV triangulation. Results: KIM was performed for 268 fractions. Various prostate trajectories were observed (ie, continuous target drift, transient excursion, stable target position, persistent excursion, high-frequency excursions, and erratic behavior). For all patients, 3D displacements of ≥3, 5, 7, and 10 mm were observed 5.6%, 2.2%, 0.7% and 0.4% of the time, respectively. The average systematic accuracy of KIM was measured at 0.46 mm. Conclusions: KIM for prostate IMAT was successfully implemented clinically for the first time. Key advantages of this method are (1) submillimeter accuracy, (2) widespread applicability, and (3) a low barrier to clinical implementation. A disadvantage is that KIM delivers additional imaging dose to the patient.

  4. Die oorsake van en bydraende faktore tot eensaamheid: 'n literatuuroorsig

    OpenAIRE

    Doman, LCH; le Roux, A

    2010-01-01

    'n Groot deel van die bevolking ervaar gereeld eensaamheid en dit word as 'n algemene verskynsel in die menslike bestaan beskou. Verskeie studies dui daarop dat jong mense veral vatbaar is vir eensaamheid. Eensaamheid word ook beskou as 'n risiko-faktor vir 'n wye verskeidenheid probleme wat 'n potensiële gevaar vir die mens se gesondheid inhou. Verskeie faktore wat 'n invloed op die mate van eensaamheid het, is ook kenmerkend van die Suid-Afrikaanse konteks. Rokach se model van eensaamheidsv...

  5. Loneliness and Internet addiction of Polish adolescents

    OpenAIRE

    Izabela Tabak; Dorota Zawadzka

    2017-01-01

    Background and aims: Internet addiction in adolescents has been a growing problem over the recent years. The aim of the study was to assess the relationships between Internet addiction, loneliness (social and emotional) and adolescents’ lower quality of life. Methods: An anonymous survey was conducted in Poland in lower and upper secondary schools on a sample of  376 students, aged 14–19. The  Young’s Diagnostic Questionnaire, the De Jong Gierveld Loneliness Scale and KIDSCREEN-10...

  6. Workshop on Diffuse Discharge Opening Switches (January 13-15, 1982).

    Science.gov (United States)

    1982-04-23

    published). 6. E. H. A. Granneman, M. Klewer, K. J. Nygaard and M. J. Van der Wiel, "Two-photon ionization of Cs2 , Rb2 and RBCs using an Ar-ion laser...G. H. Bearman and J. J. Leventhal, Phys. Rev. Lett 41, 1227 (1978). 3. A. deJong and F. van der Volk, J. Phys. B 12, L561 (1979). 225 4. F. Roussel, P...Marshall Molen Old Dominion University R.M. Patrick AVCO Everett Research Laboratory Karl Schoenbach Texas Tech University Peter Turchi R & D Associates

  7. Disease: H00146 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00146 Alpha-N-acetylgalactosaminidase deficiency, including: Schindler disease; K...ided into three types. Type 1 is Schindler disease, characterized by mental retardation, spasticity ,and myo...n alpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease). ... JOURNAL ... J Hum Genet 49:1-8 (20... ... TITLE ... The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler a...eland AM, de Jong JG, Wevers RA, Renier WO, Schindler D, Coll MJ, Chabas A, Sakuraba H, Suzuki Y, van Diggel

  8. Imaging, Sensing, And Communication Through Highly Scattering Complex Media

    Science.gov (United States)

    2015-11-24

    diameter of 20 µm, the terminal velocity would be around 0.1 m/s [Bes1950]. To test this, estimation can be made based on (19). Assuming standard air...diffuse optical tomography,” Phys. Med. Biol. 52, 3619–3641 (2007). [Can2006] E. J. Candès, J. K. Romberg , and T. Tao, “Stable signal recovery from...M. van Dam, G. Themelis, L. M. A. Crane, N. J. Harlaar, R. G. Pleijhuis, W. Kelder, A. Sarantopoulos, J. S. de Jong, H. J. G. Arts, A. G. J. van der

  9. Usamljenost žena odrasle dobi: Uloga percipirane kvalitete bračnog odnosa i samostišavanja

    OpenAIRE

    Lacković-Grgin, Katica; Nekić, Marina; Penezić, Zvjezdan

    2009-01-01

    Empirijska istraživanja u različitim kulturama konzistentno su utvrdila da su osobe u braku kao i one u izvanbračnoj zajednici manje usamljene od samaca, razvedenih i udovaca (de Jong Gierveld, 1987; Joness, Hebb, 2003). Budući da Weiss u svom interakcionističkom modelu usamljenosti naglašava da emocionalna i socijalna usamljenost nastaju kad socijalne interakcije ne osiguravaju osobi socijalne zalihe kao što su privrženost, socijalna integracija, potvrda vlastite vrijednosti i druge, razumno...

  10. Network Intrusion Dataset Assessment

    Science.gov (United States)

    2013-03-01

    International Conference on Computational Intelligence and Natural Computing, volume 2, pages 413–416, June 2009. • Rung Ching Chen, Kai -Fan Cheng, and...Chia-Fen Hsieh . “Using rough set and support vector machine for network intrusion detection.” International Journal of Network Security & Its...intrusion detection using FP tree rules.” Journal Of Advanced Networking and Applications, 1(1):30–39, 2009. • Ming-Yang Su, Gwo-Jong Yu , and Chun-Yuen

  11. The Development and Study of Molecular Electronic Switches and their Field-Effect Transistor (FET) Device Properties

    Science.gov (United States)

    2015-02-27

    Grand Rapids, MI) meetings and conferences. References 1. L.N Lucas, J.J.D. de Jong, J.H. van Esch, R.M. Kellogg , B.L. Berringa. Eur. J. Org...R.M. Kellogg , H.L. Feringa, H.L. Eur. J. Org. Chem., 2003, 155-166. 6. B. Qin, R. Yao, X. Zhao, H. Tian. Org. Biomol. Chem., 1, 2003, 2187-2191...7. L.N. Lucas, J.H. van Euch, R.M. Kellogg , B. Feringa. Chem. Comm., 1998, 2313-2314.

  12. Professionalisme met verwysing na die posisie van bedryfsielkunde en die bedryfsielkundige in Suid-Afrika

    Directory of Open Access Journals (Sweden)

    A. van der Merwe

    1981-11-01

    Bedryfsielkunde, as relatief jong maar snelgroeiende wetenskap, word aan die hand van ses kriteria vir 'n professie evalueer. Resultate in hierdie verband dui in die algemeen daarop dat die vakgebied alreeds vir 'n aantal jare in 'n oorgangsfase tot ‘n volwaardige professie is en dat daar in hierdie proses reeds ver op die professionele kontinuum gevorder is. Verdere onder-soeke ten opsigte van professionele opleiding, die statutêre organisering van Bedryfsielkunde asook 'n professionele kode en vereniging vir die Bedryfsielkunde word bepleit ten einde die professionele posisie van die vakgebied volledig te konsolideer.

  13. STUDI PERBANDINGAN ANTARA ALGORITMA BIVARIATE MARGINAL DISTRIBUTION DENGAN ALGORITMA GENETIKA

    Directory of Open Access Journals (Sweden)

    Chastine Fatichah

    2006-01-01

    Full Text Available Bivariate Marginal Distribution Algorithm is extended from Estimation of Distribution Algorithm. This heuristic algorithm proposes the new approach for recombination of generate new individual that without crossover and mutation process such as genetic algorithm. Bivariate Marginal Distribution Algorithm uses connectivity variable the pair gene for recombination of generate new individual. Connectivity between variable is doing along optimization process. In this research, genetic algorithm performance with one point crossover is compared with Bivariate Marginal Distribution Algorithm performance in case Onemax, De Jong F2 function, and Traveling Salesman Problem. In this research, experimental results have shown performance the both algorithm is dependence of parameter respectively and also population size that used. For Onemax case with size small problem, Genetic Algorithm perform better with small number of iteration and more fast for get optimum result. However, Bivariate Marginal Distribution Algorithm perform better of result optimization for case Onemax with huge size problem. For De Jong F2 function, Genetic Algorithm perform better from Bivariate Marginal Distribution Algorithm of a number of iteration and time. For case Traveling Salesman Problem, Bivariate Marginal Distribution Algorithm have shown perform better from Genetic Algorithm of optimization result. Abstract in Bahasa Indonesia : Bivariate Marginal Distribution Algorithm merupakan perkembangan lebih lanjut dari Estimation of Distribution Algorithm. Algoritma heuristik ini mengenalkan pendekatan baru dalam melakukan rekombinasi untuk membentuk individu baru, yaitu tidak menggunakan proses crossover dan mutasi seperti pada Genetic Algorithm. Bivariate Marginal Distribution Algorithm menggunakan keterkaitan pasangan variabel dalam melakukan rekombinasi untuk membentuk individu baru. Keterkaitan antar variabel tersebut ditemukan selama proses optimasi berlangsung. Aplikasi yang

  14. Book Reviews

    Directory of Open Access Journals (Sweden)

    John Bastin

    1957-10-01

    Full Text Available - P.E. de Josselin de Jong, Philip Lumban Tobing, The structure of the Toba-Batak belief in the high God. Amsterdam (Jacob van Campen 1956. (Diss. Utrecht. 177 pp., map, plates, bibl. - R. Reinsma, John Bastin, The native policies of Sir Stamford Raffles in Java and Sumatra. An Economic Interpretation, Clarendon Press: Oxford University Press, 1957; 163 blz. - A.F.P. Hulsewé, Lindsay Ride, Robert Morrison, the scholar and the man, and illustrated catalogue of the exhibition held at the University of Hongkong...to commemorate the 150th anniversary of Robert Morrison’s arrival in China; Hongkong, 1957. VIII + 48 + 24 +pp.

  15. Multifunctional Poly(2,5-benzimidazole)/Carbon Nanotube Composite Films

    Science.gov (United States)

    2010-01-01

    Multifunctional Poly(2,5- benzimidazole )/Carbon Nanotube Composite Films JI-YE KANG,1 SOO-MI EO,1 IN-YUP JEON,1 YEONG SUK CHOI,2 LOON-SENG TAN,3 JONG...molecular-weight poly(2,5- benzimidazole ) (ABPBI). ABPBI/carbon nanotube (CNT) compo- sites were prepared via in situ polymerization of the AB-monomer in the...polymerization; multiwalled carbon nanotube (MWCNT); nano- composites; poly(2,5- benzimidazole ); (ABPBI); polycondensa- tion; poly(phosphoric acid); single-walled

  16. Quality assurance for the clinical implementation of kilovoltage intrafraction monitoring for prostate cancer VMAT

    DEFF Research Database (Denmark)

    Ng, J. A.; Booth, J. T.; O'Brien, R. T.

    2014-01-01

    is being piloted in a clinical trial for prostate cancer patients treated with VMAT (NCT01742403). The purpose of this work was to develop clinical process and quality assurance (QA) practices for the clinical implementation of KIM. Methods: Informed by and adapting existing guideline documents from other...... real-time monitoring systems, KIM-specific QA practices were developed. The following five KIM-specific QA tests were included: (1) static localization accuracy, (2) dynamic localization accuracy, (3) treatment interruption accuracy, (4) latency measurement, and (5) clinical conditions accuracy. Tests...... developed and implemented for prostate cancer VMAT....

  17. Advanced Materials and Processing 2010

    Science.gov (United States)

    Zhang, Yunfeng; Su, Chun Wei; Xia, Hui; Xiao, Pengfei

    2011-06-01

    Strain sensors made from MWNT/polymer nanocomposites / Gang Yin, Ning Hu and Yuan Li -- Shear band evolution and nanostructure formation in titanium by cold rolling / Dengke Yang, Peter D. Hodgson and Cuie Wen -- Biodegradable Mg-Zr-Ca alloys for bone implant materials / Yuncang Li ... [et al.] -- Hydroxyapatite synthesized from nanosized calcium carbonate via hydrothermal method / Yu-Shiang Wu, Wen-Ku Chang and Min Jou -- Modeling of the magnetization process and orthogonal fluxgate sensitivity of ferromagnetic micro-wire arrays / Fan Jie ... [et al.] -- Fabrication of silicon oxide nanowires on Ni coated silicon substrate by simple heating process / Bo Peng and Kwon-Koo Cho -- Deposition of TiOxNy thin films with various nitrogen flow rate: growth behavior and structural properties / S.-J. Cho ... [et al.] -- Observation on photoluminescence evolution in 300 KeV self-ion implanted and annealed silicon / Yu Yang ... [et al.] -- Facile synthesis of lithium niobate from a novel precursor H[symbol] / Meinan Liu ... [et al.] -- Effects of the buffer layers on the adhesion and antimicrobial properties of the amorphous ZrAlNiCuSi films / Pai-Tsung Chiang ... [et al.] -- Fabrication of ZnO nanorods by electrochemical deposition process and its photovoltaic properties / Jin-Hwa Kim ... [et al.] -- Cryogenic resistivities of NbTiAlVTaLax, CoCrFeNiCu and CoCrFeNiAl high entropy alloys / Xiao Yang and Yong Zhang -- Modeling of centrifugal force field and the effect on filling and solidification in centrifugal casting / Wenbin Sheng, Chunxue Ma and Wanli Gu -- Electrochemical properties of TiO[symbol] nanotube arrays film prepared by anodic oxidation / Young-Jin Choi ... [et al.] -- Effect of Ce additions on high temperature properties of Mg-5Sn-3Al-1Zn alloy / Byoung Soo Kang ... [et al.] -- Sono-electroless plating of Ni-Mo-P film / Atsushi Chiba, Masato Kanou and Wen-Chang Wu -- Diameter dependence of giant magneto-impedance effect in co-based melt extracted amorphous

  18. Rheumatoid Arthritis and Complementary Medicine: In Depth

    Science.gov (United States)

    ... unproven. Many factors—including differences in tai chi styles, number of movements, length of the practice, and ... JY, Kim YJ, et al. Acupuncture for symptom management of rheumatoid arthritis: a pilot study. Clinical Rheumatology. ...

  19. Plaadid / Mart Normet

    Index Scriptorium Estoniae

    Normet, Mart, 1979-

    2006-01-01

    Uutest heliplaatidest Freddie Mercury "Lover Of Life", "World 2006", Charlotte Gainsbourg "5:55", Sam Moore "Overnight Sensational", Iain Archer "Magnetic North", Kim Wilde "Never Say Never", Tiziano Ferro "Nadie Esta Solo"

  20. ORF Alignment: NC_003143 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available regulation of aerobic, anaerobic respiration and ... osmotic balance [Yersinia pestis KIM] gb|AAS6229...onal regulation of ... aerobic, anaerobic respiration and osmotic balance ... [Yersinia pestis

  1. ORF Alignment: NC_005810 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available regulation of aerobic, anaerobic respiration and ... osmotic balance [Yersinia pestis KIM] gb|AAS6229...onal regulation of ... aerobic, anaerobic respiration and osmotic balance ... [Yersinia pestis

  2. ORF Alignment: NC_006155 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available regulation of aerobic, anaerobic respiration and ... osmotic balance [Yersinia pestis KIM] gb|AAS6229...onal regulation of ... aerobic, anaerobic respiration and osmotic balance ... [Yersinia pestis

  3. ORF Alignment: NC_004088 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available regulation of aerobic, anaerobic respiration and ... osmotic balance [Yersinia pestis KIM] gb|AAS6229...onal regulation of ... aerobic, anaerobic respiration and osmotic balance ... [Yersinia pestis

  4. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... About Media Donate Spinal Cord Injury Medical Expert Videos ... Kim Eberhardt Muir, MS Coping with a New Injury Robin Dorman, PsyD Sex and Fertility After Spinal Cord Injury Diane M. ...

  5. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... About Media Donate Spinal Cord Injury Medical Expert Videos ... Home Kim Eberhardt Muir, MS Coping with a New Injury Robin Dorman, PsyD Sex and Fertility After Spinal Cord Injury Diane M. ...

  6. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... About Media Donate Spinal Cord Injury Medical Expert Videos ... Home Kim Eberhardt Muir, MS Coping with a New Injury Robin Dorman, PsyD Sex and Fertility After Spinal Cord Injury Diane M. ...

  7. ICWIP 2008

    Indian Academy of Sciences (India)

    Scope: The 3rd IUPAP International Conference on Women in Physics (ICWIP 2008) will be held ... Maki Kawai (The Institute of Physical and Chemical Research, Japan). Young-Kee Kim ... Hyunggyu Park (Korea Institute for Advanced Study).

  8. Joonistuste näitus "Improvisatsioon" Tallinna Kunstihoones 4. VIII - 10. IX

    Index Scriptorium Estoniae

    2006-01-01

    Rahvusvahelisel näitusel osaleb üle 70 kunstniku Eestist ning külalised: Valgerdur Hauksdottir, Kim Kang, Juho Karjalainen, Solveig (Sol) Kjok, Ingrid Ledent, Roman Tolici, Peter Shvetsov, Marie Sivak. Kontserdid ja tantsuetendus koos joonistajatega

  9. DEPOSITION DISTRICUTION AMONG THE PARALLEL PATHWAYS IN THE HUMAN LUNG CONDUCTING AIRWAY STRUCTURE.

    Science.gov (United States)

    DEPOSITION DISTRIBUTION AMONG THE PARALLEL PATHWAYS IN THE HUMAN LUNG CONDUCTING AIRWAY STRUCTURE. Chong S. Kim*, USEPA National Health and Environmental Effects Research Lab. RTP, NC 27711; Z. Zhang and C. Kleinstreuer, Department of Mechanical and Aerospace Engineering, North C...

  10. Multidrug and vancomycin resistance among clinical isolates of ...

    African Journals Online (AJOL)

    2017-09-03

    Sep 3, 2017 ... Babcock University, Ilisan-Remo, Ogun State, Nigeria ... 2017 Olufunmiso et al; licensee African Health Sciences. This is an Open ..... Cole AM, Tahk S, Oren A, Yoshioka D, Kim YH, Park .... Part 2: Cambridge University press,.

  11. against booklice

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research January 2017; 16 (1): 171-177 ... Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin ..... Sinicae, Science Press, Beijing, China; 1979. ... Yeom HJ, Kang J, Kim SW, Park IK.

  12. In situ rumen degradability characteristics of rice straw, soybean ...

    African Journals Online (AJOL)

    김성진

    2012-10-05

    Oct 5, 2012 ... Abbreviations: SCR, Soybean curd residue; HPLC, high- performance liquid ... amino acids, and tocopherol which have several active functions (Ryoo et al., 2004; Kim and ..... of grape seeds extracts.' MS thesis, Sungshin ...

  13. Neuropathic pain: targeting the melatonin MT receptor

    African Journals Online (AJOL)

    inflammatory drugs (NSAIDs) and opioids is highly effective in ... to drug treatment. .... effects in chronic neuropathic pain, which are mediated by the .... Reiter R, Tan D, Kim S, Cruz M. Delivery of pineal melatonin to the brain and SCN:.

  14. Understanding the efficacy of influent waste water on microbial ...

    African Journals Online (AJOL)

    acer

    composition on the species structure and the diversity of bacterial consortia. The community ... 2010; Kim et al., 2011; Ye et al., 2011; Zhang et al.,. 2011a; b), greatly ..... molecular fine scale analysis of natural ammonia-oxidizing populations.

  15. Fabrication of organic light emitting diode using Molybdenum ...

    Indian Academy of Sciences (India)

    65

    efficiency is found to be increased compared to the single layer anode OLED. To study the ... their co-workers fabricated OLEDs on bilayer graphene electrode [5]. Daeil Kim ... On the other hand Fluorine doped Tin Oxide (FTO) though being.

  16. Bedrock geologic map of the Knox Mountain pluton area, Marshfield and Peacham, Vermont

    Data.gov (United States)

    Vermont Center for Geographic Information — Digital Data from VG08-3 Kim, J., Charnock, R., Chow, D. and Springston, G., 2008, Bedrock geologic map of the Knox Mountain pluton area, Marshfield and Peacham,...

  17. Introducing new products that affect consumer privacy : A mediation model

    NARCIS (Netherlands)

    Lancelot Miltgen, Caroline; Henseler, Jörg; Gelhard, Carsten Volker; Popovic, Ales

    2016-01-01

    Many innovative products can only fully deploy their value if they rely on consumers' personal information. This issue challenges the confidence that consumers have in new innovations, and revolutionizes marketing practices. Malhotra, Kim, and Agarwal's (2004) framework provides the theoretical

  18. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... Sores Mary Zeigler, MS Transition from Hospital to Home Kim Eberhardt Muir, MS ... advice, recommend or endorse health care products or services, or control the information found on external websites. ...

  19. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Sores Mary Zeigler, MS Transition from Hospital to Home Kim Eberhardt Muir, MS ... medical advice, recommend or endorse health care products or services, or control the information found on external websites. ...

  20. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... Sores Mary Zeigler, MS Transition from Hospital to Home Kim Eberhardt Muir, MS ... advice, recommend or endorse health care products or services, or control the information found on external websites. ...