Inlet-engine matching for SCAR including application of a bicone variable geometry inlet

Science.gov (United States)

Wasserbauer, J. F.; Gerstenmaier, W. H.

1978-01-01

Airflow characteristics of variable cycle engines (VCE) designed for Mach 2.32 can have transonic airflow requirements as high as 1.6 times the cruise airflow. This is a formidable requirement for conventional, high performance, axisymmetric, translating centerbody mixed compression inlets. An alternate inlet is defined, where the second cone of a two cone center body collapses to the initial cone angle to provide a large off-design airflow capability, and incorporates modest centerbody translation to minimize spillage drag. Estimates of transonic spillage drag are competitive with those of conventional translating centerbody inlets. The inlet's cruise performance exhibits very low bleed requirements with good recovery and high angle of attack capability.

Intraretinal proliferation induced by retinal detachment

International Nuclear Information System (INIS)

Fisher, S.K.; Erickson, P.A.; Lewis, G.P.; Anderson, D.H.

1991-01-01

Cellular proliferation after retinal detachment was studied by 3 H-thymidine light microscopic autoradiography in cats that had experimental detachments of 0.5-180 days duration. The animals underwent labeling 2 hr before death with an intraocular injection of 200 microCi of 3 H-thymidine. The number of labeled nuclei were counted in 1-micron thick tissue sections in regions of detachment, in regions of the experimental eyes that remained attached, and in control eyes that had no detachments. In the normal eye, in one that had only the lens and vitreous removed, and in the eyes with 0.5- and 1-day detachments, the number of labeled nuclei ranged from 0/mm (0.5-day detachment) to 0.38/mm (lens and vitreous removed only). By 2 days postdetachment, the number of labeled nuclei increased to 2.09/mm. The highest levels of labeling occurred in two animals with detachments of 3 (7.86/mm) and 4 (7.09/mm) days. Thereafter, the numbers declined steadily until near-baseline counts were obtained at 14 days. The number of labeled nuclei was slightly elevated in the attached regions of two animals with 3-day detachments. Labeled cell types included: Mueller cells, astrocytes, pericytes, and endothelial cells of the retinal vasculature, and both resident (microglial cells) and invading macrophages. In an earlier study RPE cells were also shown to proliferate in response to detachment. Thus, these data show that proliferation is a rapid response to detachment, reaching a maximum within 4 days, and that virtually every nonneuronal cell type in the retina can participate in this response. The data suggest that events leading to such clinical manifestations as proliferative vitreoretinopathy and subretinal fibrosis may have their beginnings in this very early proliferative response

Controlling marginally detached divertor plasmas

Science.gov (United States)

Eldon, D.; Kolemen, E.; Barton, J. L.; Briesemeister, A. R.; Humphreys, D. A.; Leonard, A. W.; Maingi, R.; Makowski, M. A.; McLean, A. G.; Moser, A. L.; Stangeby, P. C.

2017-06-01

A new control system at DIII-D has stabilized the inter-ELM detached divertor plasma state for H-mode in close proximity to the threshold for reattachment, thus demonstrating the ability to maintain detachment with minimal gas puffing. When the same control system was instead ordered to hold the plasma at the threshold (here defined as T e  =  5 eV near the divertor target plate), the resulting T e profiles separated into two groups with one group consistent with marginal detachment, and the other with marginal attachment. The plasma dithers between the attached and detached states when the control system attempts to hold at the threshold. The control system is upgraded from the one described in Kolemen et al (2015 J. Nucl. Mater. 463 1186) and it handles ELMing plasmas by using real time D α measurements to remove during-ELM slices from real time T e measurements derived from divertor Thomson scattering. The difference between measured and requested inter-ELM T e is passed to a PID (proportional-integral-derivative) controller to determine gas puff commands. While some degree of detachment is essential for the health of ITER’s divertor, more deeply detached plasmas have greater radiative losses and, at the extreme, confinement degradation, making it desirable to limit detachment to the minimum level needed to protect the target plate (Kolemen et al 2015 J. Nucl. Mater. 463 1186). However, the observed bifurcation in plasma conditions at the outer strike point with the ion B   ×  \

Inlet design for high-speed propfans

Science.gov (United States)

Little, B. H., Jr.; Hinson, B. L.

1982-01-01

A two-part study was performed to design inlets for high-speed propfan installation. The first part was a parametric study to select promising inlet concepts. A wide range of inlet geometries was examined and evaluated - primarily on the basis of cruise thrust and fuel burn performance. Two inlet concepts were than chosen for more detailed design studies - one apropriate to offset engine/gearbox arrangements and the other to in-line arrangements. In the second part of this study, inlet design points were chosen to optimize the net installed thrust, and detailed design of the two inlet configurations was performed. An analytical methodology was developed to account for propfan slipstream effects, transonic flow efects, and three-dimensional geometry effects. Using this methodology, low drag cowls were designed for the two inlets.

Self-sustained detachment observed in LHD and comparison with detachment and Marfe in W7-AS

International Nuclear Information System (INIS)

Miyazawa, J.; Masuzaki, S.; Yamada, H.; Sakamoto, R.; Peterson, B. J.; Shoji, M.; Ohyabu, N.; Komori, A.; Motojima, O.

2005-01-01

One of the crucial issues for a magnetically confined fusion reactor [1-3] is the reduction of the divertor heat load. Edge plasma cooling by increasing the density or introducing impurities such as neon as radiators is effective for reducing the divertor heat load by detaching the plasma from the divertor plates. In high-density tokamak plasmas, the so-called high-recycling regime is predicted by two-point model [4,5], where the divertor temperature (density) nonlinearly decreases (increases) with the main plasma density. Detachment takes place when the density is increased further. Then, the pressure in the flux tube is no longer conserved due to the increased radiation loss, charge exchange loss, and volume recombination. Eventually, the discharge is terminated by disruption often via rapid formation of a radiation condensation Marfe [5,6]. This scenario well explains the experimental results of tokamaks [5,7]. A similar kind of conventional detachment has been also intensively studied in a stellarator, W7-AS, after modification to the island divertor configuration [8,9]. Detachment in W7-AS is achieved by increasing the density beyond the density threshold for the high-density H-mode (HDH) [10]. As the density is increased further to the operational density limit, complete detachment takes place and, in some cases, the Marfe is formed on (or inside of) the last-closed-flux-surface (LCFS) [11-13]. These are reviewed in Section 4. Recently, a new state of self-sustained detachment has been found in LHD and named the Serpens mode (Self-regulated plasma edge neath the last-closed-flux-surface) [15,16]. In the Serpens mode, the hot plasma boundary is shrinking to equal 90 % of the LCFS radius. Large fluctuations appear in the divertor flux, H alpha and Cm signals, together with a rotating radiation belt named the serpent [17]. Detachment in LHD is observed in a significant decrease in the ion saturation current, Isat, measured on the divertor tiles [18,19]. In this

Paediatric retinal detachment: aetiology, characteristics and outcomes.

Science.gov (United States)

McElnea, Elizabeth; Stephenson, Kirk; Gilmore, Sarah; O'Keefe, Michael; Keegan, David

2018-01-01

To provide contemporary data on the aetiology, clinical features and outcomes of paediatric retinal detachment. A retrospective review of all those under 16y who underwent surgical repair for retinal detachment at a single centre between the years 2008 and 2015 inclusive was performed. In each case the cause of retinal detachment, the type of detachment, the presence or absence of macular involvement, the number and form of reparative surgeries undertaken, and the surgical outcome achieved was recorded. Twenty-eight eyes of 24 patients, 15 (62.5%) of whom were male and 9 (37.5%) of whom were female, their mean age being 11.6y and range 2-16y developed retinal detachment over the eight year period studied. Trauma featured in the development of retinal detachment in 14 (50.0%) cases. Retinal detachment was associated with other ocular and/or systemic conditions in 11 (39.3%) cases. A mean of 3.0 procedures with a range of 1-9 procedures per patient were undertaken in the management of retinal detachment. Complex vitrectomy combined with scleral buckling or complex vitrectomy alone were those most frequently performed. Mean postoperative visual acuity was 1.2 logMAR with range 0.0-3.0 logMAR. In 22 of 26 (84.6%) cases which underwent surgical repair the retina was attached at last follow-up. Aggressive management of paediatric retinal detachment including re-operation increases the likelihood of anatomical success. In cases where the retinal detachment can be repaired by an external approach alone there is a more favourable visual outcome.

Transconjunctival drainage of serous and hemorrhagic choroidal detachment.

Science.gov (United States)

Rezende, Flávio A; Kickinger, Mônica C; Li, Gisèle; Prado, Renata F; Regis, Luiz Gustavo T

2012-02-01

To describe a novel surgical technique for drainage of bullous serous and hemorrhagic choroidal detachments. A prospective, consecutive case series of 6 eyes with serous and/or hemorrhagic choroidal detachments secondary to intraocular surgery was documented to evaluate the feasibility of using the 25-gauge and 20-gauge transconjunctival trocar/cannula systems to drain choroidal detachments. Two eyes had expulsive hemorrhagic choroidal detachments and 4 eyes had serous choroidal detachments after glaucoma surgeries. A 25-gauge infusion line was placed in the anterior chamber. A 20-gauge (in eyes with hemorrhagic choroidal detachments) or a 25-gauge (in eyes with serous detachments) trocar/cannula system was inserted into the suprachoroidal space 7.0 mm from limbus. After drainage, the cannulas were removed and no sutures were placed. Pars plana vitrectomy was performed only in eyes with concomitant pathology that demanded the additional procedure. The primary outcome measure was presence of choroidal detachment at 1 week, 2 weeks, and 1 month postoperatively. Secondary outcome measures were visual acuity at 6 months and intraocular pressure at 1 week and 1, 3, and 6 months postoperatively. Drainage of hemorrhagic choroidal detachments resulted in resolution of the detachments by 1 month postoperatively. In eyes with serous detachments, resolution was achieved by 1 week postdrainage. In both groups, intraocular pressure increased to at least 10 mmHg by postoperative Week 1. The visual acuity improved in all eyes. No complications related to the transconjunctival technique were noted. Transconjunctival drainage of serous and hemorrhagic choroidal detachments seems to be a feasible and simple surgical option with minimal scleral and conjunctival damage. Pars plana vitrectomy may not be necessary when draining choroidal detachments in this manner.

Paediatric retinal detachment: aetiology, characteristics and outcomes

Directory of Open Access Journals (Sweden)

Elizabeth McElnea

2018-02-01

Full Text Available AIM: To provide contemporary data on the aetiology, clinical features and outcomes of paediatric retinal detachment. METHODS: A retrospective review of all those under 16y who underwent surgical repair for retinal detachment at a single centre between the years 2008 and 2015 inclusive was performed. In each case the cause of retinal detachment, the type of detachment, the presence or absence of macular involvement, the number and form of reparative surgeries undertaken, and the surgical outcome achieved was recorded. RESULTS: Twenty-eight eyes of 24 patients, 15 (62.5% of whom were male and 9 (37.5% of whom were female, their mean age being 11.6y and range 2-16y developed retinal detachment over the eight year period studied. Trauma featured in the development of retinal detachment in 14 (50.0% cases. Retinal detachment was associated with other ocular and/or systemic conditions in 11 (39.3% cases. A mean of 3.0 procedures with a range of 1-9 procedures per patient were undertaken in the management of retinal detachment. Complex vitrectomy combined with scleral buckling or complex vitrectomy alone were those most frequently performed. Mean postoperative visual acuity was 1.2 logMAR with range 0.0-3.0 logMAR. In 22 of 26 (84.6% cases which underwent surgical repair the retina was attached at last follow-up. CONCLUSION: Aggressive management of paediatric retinal detachment including re-operation increases the likelihood of anatomical success. In cases where the retinal detachment can be repaired by an external approach alone there is a more favourable visual outcome.

Study on imaging diagnosis of the ciliochoroidal detachment

International Nuclear Information System (INIS)

Shi Dapeng; Feng Gansheng; Li Shuyin

2008-01-01

Objective: To investigate the characteristics of imaging appearances and diagnostic value of ciliochoroidal detachment. Methods: Ultrasound, MRI and CT appearances of 19 eases of ciliochoroidal detachment were reviewed, which included 9 cases of serous ciliochoroidal detachment, 7 cases of choroid hematoma, and 3 cases of ciliary, body detachment. All cases were examined by both B ultrasound and MRI at the same time, 11 of them were examined by CT. Results: Ultrasound showed membrane bulge of the eyeball wall with different extent in 9 cases of serous ciliochoroidal detachment. Its postzone connected the equator or close to optic disc and its prozone could not been detected by ultrasound. There was echofree fluid darkspace under detached membrane. MRI showed membrane detachment at both nasal side and temporal side of ocular annelation in 9 cases of ciliochoroidal detachment. The detached membrane was approximately symmetry, its anterior margin did not exceed ciliary body adhesion of ocular annelation and its posterior margin stopped at posterior part of ocular annelation. There was long T 1 and long T 2 signal under detached membrane. CT showed slight thickening of ocular annelation and slightly increased density of eyeball in 5 eases of serous ciliochoroidal detachment. Ultrasound showed hemispheroid or curve bulge of eyeball wall, projected toward the vitreous cavity in 7 cases of choroid hematoma, and there was an amount of low echo light spot under the detached membrane. Both MRI (7 cases) and CT (5 cases) showed hemispheroid, fusiform or curve bulge on the nasal side, temporal side and posterior part of ocular annelation. They appeared as isodensity or slight high density on CT, iso- or high signal on T 1 WI and T 2 WI. Stratification was seen on T 2 WI in 1 case of choroid hematoma. Ciliary body detachment could not been detected by either MRI (3 cases) or CT (1 case) except ultrasound. Conclusion: Imaging examination may provide reliable diagnostic evidence

Retinal Detachment

Science.gov (United States)

... to your brain. It provides the sharp, central vision needed for reading, driving, and seeing fine detail. A retinal detachment lifts or pulls the retina from its normal position. It can occur at ...

A history of detachable coils: 1987-2012.

Science.gov (United States)

Hui, Ferdinand K; Fiorella, David; Masaryk, Thomas J; Rasmussen, Peter A; Dion, Jacques E

2014-03-01

The development of detachable coils is one of the most pivotal developments in neurointervention, providing a tool that could be used to treat a wide variety of hemorrhagic stroke. From the original Guglielmi detachable coil, a number of different coil designs and delivery designs have evolved. This article reviews the history of commercially available detachable coils. A timeline of detachable coils was constructed and coil design philosophies were reviewed. A complete list of commercially available coils is presented in a timeline format. Detachable coil technology continues to evolve. Advances in construction and design have yielded products which may benefit patients in terms of safety, radiation dose reduction and cost of treatment. Continued evolution is expected, irrespective of competing disruptive technologies.

A Tale of Two Inlets: Tidal Currents at Two Adjacent Inlets in the Indian River Lagoon

Science.gov (United States)

Webb, B. M.; Weaver, R. J.

2012-12-01

The tidal currents and hydrography at two adjacent inlets of the Indian River Lagoon estuary (Florida) were recently measured using a personal watercraft-based coastal profiling system. Although the two inlets—Sebastian Inlet and Port Canaveral Inlet—are separated by only 60 km, their characteristics and dynamics are quite unique. While Sebastian Inlet is a shallow (~4 m), curved inlet with a free connection to the estuary, Port Canaveral Inlet is dominated by a deep (~13 m), straight ship channel and has limited connectivity to the Banana River through a sector gate lock. Underway measurements of tidal currents were obtained using a bottom tracking acoustic Doppler current profiler; vertical casts of hydrography were obtained with a conductivity-temperature-depth profiling instrument; and continuous underway measurements of surface water hydrography were made using a Portable SeaKeeper system. Survey transects were performed to elucidate the along-channel variability of tidal flows, which appears to be significant in the presence of channel curvature. Ebb and flood tidal currents in Sebastian Inlet routinely exceeded 2.5 m/s from the surface to the bed, and an appreciable phase lag exists between tidal stage and current magnitude. The tidal currents at Port Canaveral Inlet were much smaller (~0.2 m/s) and appeared to be sensitive to meteorological forcing during the study period. Although the lagoon has free connections to the ocean 145 km to the north and 45 km to the south, Sebastian Inlet likely drains much of the lagoon to its north, an area of ~550 sq. km.

[Surgical managment of retinal detachment].

Science.gov (United States)

Haritoglou, C; Wolf, A

2015-05-01

The detachment of the neurosensory retina from the underlying retinal pigment epithelium can be related to breaks of the retina allowing vitreous fluid to gain access to the subretinal space, to exudative changes of the choroid such as tumours or inflammatory diseases or to excessive tractional forces exerted by interactions of the collagenous vitreous and the retina. Tractional retinal detachment is usually treated by vitrectomy and exudative detachment can be addressed by treatment of the underlying condition in many cases. In rhegmatogenous retinal detachment two different surgical procedures, vitrectomy and scleral buckling, can be applied for functional and anatomic rehabilitation of our patients. The choice of the surgical procedure is not really standardised and often depends on the experience of the surgeon and other more ocular factors including lens status, the number of retinal breaks, the extent of the detachment and the amount of preexisting PVR. Using both techniques, anatomic success rates of over 90 % can be achieved. Especially in young phakic patients scleral buckling offers the true advantage to prevent the progression of cataract formation requiring cataract extraction and intraocular lens implantation. Therefore, scleral buckling should be considered in selected cases as an alternative surgical option in spite of the very important technical refinements in modern vitrectomy techniques. Georg Thieme Verlag KG Stuttgart · New York.

Variable geometry for supersonic mixed-compression inlets

Science.gov (United States)

Sorensen, N. E.; Latham, E. A.; Smeltzer, D. B.

1974-01-01

Study of two-dimensional and axisymmetric supersonic mixed-compression inlet systems has shown that the geometry of both systems can be varied to provide adequate transonic airflow to satisfy the airflow demand of most jet engines. Collapsing geometry systems for both types of inlet systems provide a generous amount of transonic airflow for any design Mach number inlet system. However, the mechanical practicality of collapsing centerbodies for axisymmetric inlet systems is doubtful. Therefore, translating centerbody axisymmetric inlets with auxiliary airflow systems to augment the transonic airflow capability are an attractive alternative. Estimates show that the capture mass-flow ratio at Mach number 1.0 can be increased approximately 0.20 for a very short axisymmetric inlet system designed for Mach number 2.37. With this increase in mass-flow ratio, even variable-cycle engine transonic airflow demand can be matched without oversizing the inlet at the design Mach number.

Risk of retinal detachment in patients with lattice degeneration.

Science.gov (United States)

Sasaki, K; Ideta, H; Yonemoto, J; Tanaka, S; Hirose, A; Oka, C

1998-01-01

To determine the risk of retinal detachment in patients with lattice degeneration of the retina, we statistically analyzed the incidence of retinal detachment in these patients. The data of hospital patients with retinal detachment associated with lattice degeneration in Kumamoto Prefecture, Japan, in 1990 were collected. The prevalence of lattice degeneration in Kumamoto was reported to be 9.5% in 1980. Based on population data from the 1990 census, the cumulative incidence of retinal detachment associated with lattice degeneration was calculated in this study. Among 1,840,000 residents in Kumamoto, there were 110 patients with retinal detachment associated with lattice degeneration; 72 with detachment resulting from tractional tears (tears), and 38 with detachment from atrophic holes. The cumulative incidence of retinal detachment from atrophic holes was 1.5% at the age of 40 years; from tears it was 3.6% at the age of 80 years. The cumulative incidence of detachment from both atrophic holes and tears was 5.3% at the age of 80 years. The results of this study are useful for clarifying the natural course of lattice degeneration.

Frictional and elastic energy in gecko adhesive detachment.

Science.gov (United States)

Gravish, Nick; Wilkinson, Matt; Autumn, Kellar

2008-03-06

Geckos use millions of adhesive setae on their toes to climb vertical surfaces at speeds of over 1 m s(-1). Climbing presents a significant challenge for an adhesive since it requires both strong attachment and easy, rapid removal. Conventional pressure-sensitive adhesives are either strong and difficult to remove (e.g. duct tape) or weak and easy to remove (e.g. sticky notes). We discovered that the energy required to detach adhering tokay gecko setae (W(d)) is modulated by the angle (theta) of a linear path of detachment. Gecko setae resist detachment when dragged towards the animal during detachment (theta = 30 degrees ) requiring W(d) = 5.0+/-0.86(s.e.) J m(-2) to detach, largely due to frictional losses. This external frictional loss is analogous to viscous internal frictional losses during detachment of pressure-sensitive adhesives. We found that, remarkably, setae possess a built-in release mechanism. Setae acted as springs when loaded in tension during attachment and returned elastic energy when detached along the optimal path (theta=130 degrees ), resulting in W(d) = -0.8+/-0.12 J m(-2). The release of elastic energy from the setal shaft probably causes spontaneous release, suggesting that curved shafts may enable easy detachment in natural, and synthetic, gecko adhesives.

Risk of Retinal Detachment After Pediatric Cataract Surgery

DEFF Research Database (Denmark)

Haargaard, Birgitte; Andersen, Elisabeth W; Oudin, Anna

2014-01-01

PURPOSE: To determine the long-term risk of retinal detachment following pediatric cataract surgery and to identify risk factors for retinal detachment. METHODS: We included all children (aged 0 to 17 years) who during the time period of 1977 to 2005 underwent pediatric cataract surgery in Denmark...... was based on medical chart review. RESULTS: Among 1043 eyes of 656 children undergoing surgery for pediatric cataract, 25 eyes (23 children) developed retinal detachment at a median time of 9.1 years after surgery. The overall 20-year risk of retinal detachment was 7% (95% confidence interval [CI]: 3...... (16% [95% CI: 6%-24%]). CONCLUSIONS: The estimated overall risk of retinal detachment 20 years after pediatric cataract surgery was 7%, but only 3% for isolated cataract. Particularly high risks of retinal detachment after cataract surgery were associated with mental retardation and having other...

Retinal Detachment

Directory of Open Access Journals (Sweden)

Adnan Riaz, MD

2018-04-01

Full Text Available History of present illness: A 58-year-old female presented to the emergency department reporting six days of progressive, atraumatic left eye vision loss. Her symptoms started with the appearance of dark spots and “spider webs,” and then progressed to darkening of vision in her left eye. She reports mild pain since yesterday. Her review of symptoms was otherwise negative. Ocular physical examination revealed normal external appearance, intact extraocular movements, and visual acuities of 20/25 OD and light/dark sensitivity OS. Fluorescein uptake was negative and slit lamp exam was unremarkable. Significant findings: Bedside ocular ultrasound revealed a serpentine, hyperechoic membrane that appeared tethered to the optic disc posteriorly with hyperechoic material underneath. These findings are consistent with retinal detachment (RD and associated retinal hemorrhage. Discussion: The retina is a layer of organized neurons that line the posterior portion of the posterior chamber of the eye. RD occurs when this layer separates from the underlying epithelium, resulting in ischemia and progressive photoreceptor degeneration, with potentially rapid and permanent vision loss if left untreated.1 Risk factors include advanced age, male sex (60%, race (Asians and Jews, and myopia and lattice degeneration.2 Bedside ultrasound (US performed by emergency physicians provides a valuable tool that has been used by ophthalmologists for decades to evaluate intraocular disease.1,3 Findings on bedside ultrasound consistent with RD include a hyperechoic membrane floating in the posterior chamber. RD usuallyremain tethered to the optic disc posteriorly and do not cross midline, a feature distinguishing them from posterior vitreous detachments. Associated retinal hemorrhage, seen as hyperechoic material under the retinal flap, can often be seen.1,2 US can also distinguish between “mac-on” and “mac-off” detachments. If the retina is still attached to the

Chronostratigraphic Analysis of Geomorphic Features within the Former Sinepuxent Inlet: A Wave-Dominated Tidal Inlet along Assateague Island, MD, USA

Science.gov (United States)

Seminack, C.; McBride, R.; Petruny, L. M.

2017-12-01

The former Sinepuxent Inlet, located along the mixed-energy, wave-dominated Assateague Island, MD-VA, USA, contains some of the most robust recurved-spit ridges along the span of the barrier island. In addition, this former tidal inlet exhibits a poorly developed flood-tidal delta containing at least two sets of curvilinear ridges known as "washarounds". Historical maps and nautical charts indicate that the former Sinepuxent Inlet was open from 1755 to 1832. However, previous studies conducted at the former Sinepuxent Inlet hypothesized that the site was exposed to episodic breaching events because of the extensive width of the former inlet throat, constrained by the northern and southern recurved-spit ridges. A total of 16 sediment cores, 10 optically stimulated luminescence (OSL) samples, and three 14C samples (mixed benthic foraminifera and eastern mud snail [Ilyanassa obsolete]) were collected from the former Sinepuxent Inlet to place morphostratigraphic units into a chronological context. Six OSL samples were collected from the northern and southern recurved-spit ridges at mean sea level (MSL) to constrain genesis ages. Southern recurved-spit ages varied more than their northern counterparts, ranging from 1640 to 1990 AD. The northern recurved-spit ridges varied in age from 1770 to 1900 AD. Two OSL samples collected from flood-tidal delta ridges yielded ages from 1680 to 2000 AD. In addition, two 14C samples collected at 128 and 101 cm below MSL within the inlet throat yielded ages between 1720 and post-1950 AD. Ultimately, these dates overlap with the inlet activity phase as indicated in historical documents. Conversely, two OSL samples (155 and 201 cm below MSL) and one 14C sample (134 cm below MSL) collected from the inlet throat returned ages between 760 and 1465 AD. The contrast in ages between the older inlet throat and subaerial ridge samples supports the hypothesis that the former Sinepuxent Inlet was reactivated numerous times. Thus, the three age

Inlet-engine matching for SCAR including application of a bicone variable geometry inlet. [Supersonic Cruise Aircraft Research

Science.gov (United States)

Wasserbauer, J. F.; Gerstenmaier, W. H.

1978-01-01

Airflow characteristics of variable cycle engines (VCE) designed for Mach 2.32 can have transonic airflow requirements as high as 1.6 times the cruise airflow. This is a formidable requirement for conventional, high performance, axisymmetric, translating centerbody mixed compression inlets. An alternate inlet is defined where the second cone of a two cone centerbody collapses to the initial cone angle to provide a large off-design airflow capability, and incorporates modest centerbody translation to minimize spillage drag. Estimates of transonic spillage drag are competitive with those of conventional translating centerbody inlets. The inlet's cruise performance exhibits very low bleed requirements with good recovery and high angle of attack capability.

Coastal inlets and tidal basins

NARCIS (Netherlands)

De Vriend, H.J.; Dronkers, J.; Stive, M.J.F.; Van Dongeren, A.; Wang, J.H.

2002-01-01

lecture note: Tidal inlets and their associated basins (lagoons) are a common feature of lowland coasts all around the world. A significant part ofthe world's coastlines is formed by barrier island coasts, and most other tidal coasts are interrupted by estuaries and lagoon inlets. These tidal

Retinal detachment repair

Science.gov (United States)

... medicines Problems breathing You may not recover full vision. ... detachments can be repaired. Failure to repair the retina always results in loss of vision to some degree. After surgery, the quality of ...

Retinal detachment in paediatric patients

International Nuclear Information System (INIS)

Zafar, S. N.; Qureshi, N.; Azad, N.; Khan, A.

2013-01-01

Objective: To assess the causes of retinal detachment in children and the various operative procedures requiring vitreoretinal surgical intervention for the same. Study Design: Case series. Place and Duration of Study: Department of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, from January 2006 to May 2009. Methodology: A total of 281 eyes of 258 patients, (aged 0 - 18 years) who underwent vitreo-retinal surgical intervention for retinal detachment were included. Surgical log was searched for the type of retinal detachment and its causes. Frequencies of various interventions done in these patients viz. vitrectomy, scleral buckle, use of tamponading agents, laser photocoagulation and cryotherapy were noted. Results were described as descriptive statistics. Results: Myopia was the cause in 62 (22.1%) and trauma in 51 (18.1%) of the eyes. Total retinal detachment (RD) was treated in 94 (33.5%) eyes, sub total RD in 36 (12.8%), recurrent RD in 32 (11.4%), giant retinal tear in 28 (10%), tractional RD in 15 (5.3%) and exudative RD in 2 (0.7%). Prophylactic laser or cryotherapy was applied in 74 (26.3%) of the eyes. Pars plana vitrectomy (PPV) was carried out in 159 (56.6%) eyes while scleral buckle procedure was done in 129 (45.9%) eyes. Silicon oil was used in 149 (53%), perfluorocarbon liquid in 32 (11.4%) and gas tamponade in 20 (7.1%) eyes. Conclusion: The most common cause of retinal detachment in paediatric patients was myopia, followed by trauma. Total RD was more common as compared to the other types. The most common procedure adopted was pars plana vitrectomy followed by scleral buckle procedure. (author)

The prognosis of retinal detachment due to lattice degeneration.

Science.gov (United States)

Benson, W E; Morse, P H

1978-09-01

In a series of 553 consecutive retinal detachments, 29% (120) were due to lattice degeneration. Forty-five percent of these were due to atrophic holes in the lattice degeneration and 55% were due to tears caused by traction posterior to or at the end of a patch of lattice. In phakic patients, retinal detachments due to atrophic holes were most common in young myopes. Detachments due to traction tears were seen in older, less myopic patients. The incidence of massive periretinal proliferation was less (5%) in detachments due to lattice degeneration than in detachments not due to lattice degeneration (6.5%).

Reconstruction of paleo-inlet dynamics using sedimentologic analyses, geomorphic features, and benthic foraminiferal assemblages: former ephemeral inlets of Cedar Island, Virginia, USA

Science.gov (United States)

McBride, R.; Wood, E. T.

2017-12-01

Cedar Island, VA is a low-profile, washover-dominated barrier island that has breached at least three times in the past sixty years. Cedar Island Inlet, a former wave-dominated tidal inlet, was open for the following time periods: 1) 1956-1962, 2) 1992-1997, and 3) 1998-2007. Air photos, satellite imagery, and geomorphic features (i.e., relict flood tidal deltas, recurved-spit ridges) record the spatial and temporal extent of the three ephemeral inlets. Based on three sediment vibracores, benthic foraminiferal and sedimentologic analyses offer high resolution insights of inlet dynamics and lifecycle evolution. Four foraminiferal biofacies are completely dominated by Elphidium excavatum (54-100%) and contain unique assemblages of accessory species based on cluster analyses: tidal inlet floor (low abundance estuarine and shelf species; 23% Haynesina germanica); flood tidal delta/inlet fill (high abundance estuarine and shelf species; 2% Buccella frigida, 2% Ammonia parkinsoniana, and 2% Haynesina germanica); high-energy inlet fill (low abundance, low diversity shelf species; 9% Elphidium gunteri); and washover/beach/aeolian (low abundance, predominantly shelf species; 3% Buccella frigida and 3% Ammonia parkinsoniana). The estuarine biofacies is barren of all foraminifera. Grain size trends indicate a first order coarsening-upward succession with second order coarsening- and fining-upwards packages in inlet throat deposits, while a first order fining-upward succession is observed in flood tidal delta deposits with two second order coarsening-upward packages in the proximal flood tidal delta. Contrary to typical wave-dominated tidal inlets that open, migrate laterally in the direction of net longshore transport, and close, the 1998-2007 tidal inlet, and possibly the 1956-1962 inlet, migrated laterally and rotated, whereas the 1992-1997 inlet remained stationary and did not rotate. In the vicinity of the vibracores, preserved deposits are attributed to the 1956-1962 and

Fluctuation characteristics in detached recombining plasmas

International Nuclear Information System (INIS)

Ohno, Noriyasu; Tanaka, Naoyuki; Takamura, Shuichi; Budaev, Viatcheslav

2002-01-01

Fluctuation in detached recombining plasmas has been investigated experimentally in the linear divertor plasma simulator, NAGDIS-II. As increasing neutral gas pressure, floating potential fluctuation of the target plate installed at the end of the NADIS-II device becomes larger and bursty negative spikes are observed in the signal associated with a transition from attached to detached a plasmas. The fluctuation property has been analyzed by using Fast Fourier Transform (FFT), probability distribution function (PDF) and wavelet transform. The PDF of the floating potential fluctuation in the attached plasma condition obeys the Gaussian distribution function, on the other hand, the PDF in detached plasma shows a strong deviation from the Gaussian distribution function, which can be characterized by flatness and skewness. Comparison of the fluctuation properties between the floating potential and the optical emission from the detached plasma has been done based on the wavelet transform to show that a strong correlation between them, which could indicate bursty transport of energetic electrons from upstream to downstream region along the magnetic field. (author)

Performance study for inlet installations

Science.gov (United States)

Bingaman, Donald C.

1992-01-01

A conceptual design trade study was conducted by McDonnell Aircraft Company (MCAIR) and NASA LARC PAB to determine the impact of inlet design features incorporated for reduced detectability on inlet performance, weight, and cost, for both fighter and attack-type aircraft. Quality Function Deployment (QFD) techniques were used to prioritize trade study issues, and select 'best' air induction system configurations for each of two notional aircraft, the Multi-Role Fighter (MRF) and the Advanced Medium Attack (AMA) bomber. Database deficiencies discovered in the trade study process were identified, and technology roadmaps were developed to address these deficiencies. Finally, two high speed inlet wind tunnel model concepts were developed for follow-on wind tunnel investigations.

Ocular hemodynamics in patients with rhegmatogenous retinal detachment

Directory of Open Access Journals (Sweden)

N. H. Zavgorodnya

2014-10-01

Full Text Available Aim. In case of retinal detachment atrophic processes lead to irreversible loss of functions within 4–6 days, it happens on underlying low ocular blood flow. In order to evaluate the degree of violation of regional hemodynamics in patients with retinal detachment two groups of patients were examined: the main group (52 patients with rhegmatogenous retinal detachment and the control group (24 myopic patients with lattice form of peripheral chorioretinal dystrophy. Methods and results. Doppler and reography results had been compared, significant decrease of blood flow in patients with retinal detachment was found. No differences between affected and fellow eye in these patients, close negative correlation between the level of ocular blood flow and the degree of myopia in the control group. Conclusion. This demonstrates the feasibility of actions to improve regional blood flow in patients operated on for retinal detachment.

Investigation on inlet recirculation characteristics of double suction centrifugal compressor with unsymmetrical inlet

Science.gov (United States)

Yang, Ce; Wang, Yingjun; Lao, Dazhong; Tong, Ding; Wei, Longyu; Liu, Yixiong

2016-08-01

The inlet recirculation characteristics of double suction centrifugal compressor with unsymmetrical inlet structures were studied in numerical method, mainly focused on three issues including the amounts and differences of the inlet recirculation in different working conditions, the circumferential non-uniform distributions of the inlet recirculation, the recirculation velocity distributions of the upstream slot of the rear impeller. The results show that there are some differences between the recirculation of the front impeller and that of the rear impeller in whole working conditions. In design speed, the recirculation flow rate of the rear impeller is larger than that of the front impeller in the large flow range, but in the small flow range, the recirculation flow rate of the rear impeller is smaller than that of the front impeller. In different working conditions, the recirculation velocity distributions of the front and rear impeller are non-uniform along the circumferential direction and their non-uniform extents are quite different. The circumferential non-uniform extent of the recirculation velocity varies with the working conditions change. The circumferential non-uniform extent of the recirculation velocity of front impeller and its distribution are determined by the static pressure distribution of the front impeller, but that of the rear impeller is decided by the coupling effects of the inlet flow distortion of the rear impeller, the circumferential unsymmetrical distribution of the upstream slot and the asymmetric structure of the volute. In the design flow and small flow conditions, the recirculation velocities at different circumferential positions of the mean line of the upstream slot cross-section of the rear impeller are quite different, and the recirculation velocities distribution forms at both sides of the mean line are different. The recirculation velocity distributions in the cross-section of the upstream slot depend on the static pressure

Risk of progression in macula-on rhegmatogenous retinal detachment.

Science.gov (United States)

Callizo, Josep; Pfeiffer, Sebastian; Lahme, Eva; van Oterendorp, Christian; Khattab, Mohammed; Bemme, Sebastian; Kulanga, Miroslav; Hoerauf, Hans; Feltgen, Nicolas

2017-08-01

To identify factors that may lead to a rapid progression in macula-on rhegmatogenous retinal detachment (RRD), in particular, those that may lead to macular involvement. Observational, prospective, single-center study. Patients referred for surgery due to primary rhegmatogenous retinal detachment with the macula on between 2009 and 2013 were included. Relevant factors analyzed included age, time delay until surgery, lens status, myopia, the detachment's location and configuration as well as number, size and type of retinal breaks. Eyes underwent optical coherence tomography to detect macular detachment. A multivariate analysis was performed to investigate the effect of several factors in the progression of retinal detachment. A total of 116 eyes of 116 patients were included. Mean time delay between admission and surgery was 1.8 ± 1.4 days. Progression was observed in 19.8% of the eyes. Of those, 47.8% presented macular detachment. Ten of the 11 (90.9%) eyes presenting progression involving the macula also exhibited a bullous configuration, which was the only parameter that correlated significantly with detachment progression in patients with (p = 0.0036) and without (p = 0.0014) macular involvement. For the first time in a prospective trial, a bullous configuration was found to be a highly significant predictor for progression in macula-on detachments. Our data support prompt surgery in patients diagnosed with bullous macula-on RRD.

Posterior vitreous detachment and retinal detachment after cataract surgery.

Science.gov (United States)

Ripandelli, Guido; Coppé, Andrea Maria; Parisi, Vincenzo; Olzi, Diego; Scassa, Cecilia; Chiaravalloti, Adele; Stirpe, Mario

2007-04-01

To evaluate possible changes of vitreous status in emmetropic eyes after uneventful phacoemulsification surgery, and possible related complications such as the onset of retinal detachment (RD). Retrospective case series. Four hundred fifty-three emmetropic eyes from 453 patients (mean age, 62.03+/-5.57 years) subjected to uneventful phacoemulsification with intraocular lens implantation in the capsular bag were considered in the study. They had a refractive error within +/-0.5 diopters (mean, -0.21+/-0.08). Eyes with peripheral retinal lattice degeneration were included only if asymptomatic and only if the degeneration involved one retinal quadrant. After cataract surgery, the 453 eyes were evaluated preoperatively at days 1, 15, and 30 and months 3, 6, 12, 18, 24, 36, 48, and 60. The whole period of follow-up was 5 years. Evaluation of vitreous status by biomicroscopic examination, indirect binocular ophthalmoscopy, and B-scan ultrasonography. Postoperative onset of posterior vitreous detachment (PVD) and RD. After cataract surgery, a PVD occurred in 107 of 141 (75.88%) eyes without preoperative PVD or lattice degeneration. Posterior vitreous detachment occurred in 41 of 47 eyes (87.23%) with preoperative lattice degeneration and no PVD. Eyes with preoperative lattice degeneration and postoperative PVD showed a higher incidence of RD after cataract surgery (21.27%) than eyes without preoperative PVD or lattice degeneration (0.70%). In all patients with lattice degeneration, RD originated from horseshoe retinal tears on lattice areas located on the superior quadrants. No correlation was observed between the development of RD and age. Our results suggest that the onset of postoperative PVD should be considered an important risk factor for the development of RD after cataract surgery, particularly in eyes with lattice areas.

The potential and need for energy saving in standard family detached and semi-detached wooden houses in arctic Greenland

DEFF Research Database (Denmark)

Bjarløv, Søren Peter; Vladyková, Petra

2011-01-01

The paper gives an account of the potential and need for energy saving in standard family detached and semi-detached wooden houses in Greenland. It is based on studies of house construction compared with Building Regulation requirements and the spread of buildings over time. In the climatic...... conditions of Greenland, there is considerable potential for energy saving in houses due to their construction, shape and condition. To estimate the total potential for energy saving and thus reducing CO2 emissions, we carried out a detailed investigation of three typical standard semi-detached family houses...

A review of direct experimental measurements of detachment

Science.gov (United States)

Boedo, J.; McLean, A. G.; Rudakov, D. L.; Watkins, J. G.

2018-04-01

Detached divertor plasmas feature strong radial and parallel gradients of density, temperature, electric fields and flow over the divertor volume and therefore, sampling the divertor plasma directly provides crucial knowledge to the interpretation and modeling efforts. We review the contribution of diagnostics that directly sample the plasma to the advancement of knowledge of the physics of detachment and detached divertors, such as the characteristics of the various regimes, discovery and quantification of drifts and identification of convection of heat and particles. We focus on wall probes, scanning probes, retarding field analyzers and Thomson scattering in the divertor region and also include the contribution of measurements away from the divertor that provide insight on how divertor detachment affects core, edge or pedestal conditions. Wall probes are critical as they can be installed in closed volumes of difficult access to other diagnostics and measure plasma parameters at the divertor structures, which define the plasma boundary conditions and where detachment effects are more likely to be strongest.

Tractional retinal detachment in Usher syndrome type II.

Science.gov (United States)

Rani, Alka; Pal, Nikhil; Azad, Raj Vardhan; Sharma, Yog Raj; Chandra, Parijat; Vikram Singh, Deependra

2005-08-01

Retinal detachment is a rare complication in patients with retinitis pigmentosa. A case is reported of tractional retinal detachment in a patient with retinitis pigmentosa and sensorineural hearing loss, which was diagnosed as Usher syndrome type II. Because of the poor visual prognosis, the patient refused surgery in that eye. Tractional retinal detachment should be added to the differential diagnoses of visual loss in patients with retinitis pigmentosa.

Transition in plasma fluctuation between attached and detached plasmas

International Nuclear Information System (INIS)

Okazaki, Katsuya; Ohno, Noriyasu; Kajita, Shin; Tanaka, Hirohiko

2012-01-01

The static and dynamic behaviors of detached plasmas have received considerable attention because the use of a detached divertor is thought to provide a promising method for reducing the heat flux to plasma-facing components. In this study, fluctuations were measured with an electrostatic probe as the plasma was changed from attached to detached states by increasing the neutral gas pressure. The transition from an attached plasma to a detached plasma was found to change the phase relation between the density and the potential. (author)

A computer investigation of chemically mediated detachment in bacterial biofilms.

Science.gov (United States)

Hunt, Stephen M; Hamilton, Martin A; Sears, John T; Harkin, Gary; Reno, Jason

2003-05-01

A three-dimensional computer model was used to evaluate the effect of chemically mediated detachment on biofilm development in a negligible-shear environment. The model, BacLAB, combines conventional diffusion-reaction equations for chemicals with a cellular automata algorithm to simulate bacterial growth, movement and detachment. BacLAB simulates the life cycle of a bacterial biofilm from its initial colonization of a surface to the development of a mature biofilm with cell areal densities comparable to those in the laboratory. A base model founded on well established transport equations that are easily adaptable to investigate conjectures at the biological level has been created. In this study, the conjecture of a detachment mechanism involving a bacterially produced chemical detachment factor in which high local concentrations of this detachment factor cause the bacteria to detach from the biofilm was examined. The results show that the often observed 'mushroom'-shaped structure can occur if detachment events create voids so that the remaining attached cells look like mushrooms.

Sediment Budget Analysis; Masonboro Inlet, North Carolina

Science.gov (United States)

2017-08-15

ER D C/ CH L TR -1 7- 13 Regional Sediment Management (RSM) Program Sediment Budget Analysis; Masonboro Inlet, North Carolina Co as ta...ERDC/CHL TR-17-13 August 2017 Sediment Budget Analysis; Masonboro Inlet, North Carolina Kevin B. Conner U.S. Army Engineer District, Wilmington P...Engineers Washington, DC 20314-1000 Under Project 454632, “Sediment Budget Analysis, Masonboro Inlet, NC” ERDC/CHL TR-17-13 ii Abstract A

Detached Bridgman Growth of Germanium and Germanium-Silicon Alloy Crystals

Science.gov (United States)

Szofran, F. R.; Volz, M. P.; Schweizer, M.; Cobb, S. D.; Motakef, S.; Croell, A.; Dold, P.; Curreri, Peter A. (Technical Monitor)

2002-01-01

Earth based experiments on the science of detached crystal growth are being conducted on germanium and germanium-silicon alloys (2 at% Si average composition) in preparation for a series of experiments aboard the International Space Station (ISS). The purpose of the microgravity experiments includes differentiating among proposed mechanisms contributing to detachment, and confirming or refining our understanding of the detachment mechanism. Because large contact angle are critical to detachment, sessile drop measurements were used to determine the contact angles as a function of temperature and composition for a large number of substrates made of potential ampoule materials. Growth experiments have used pyrolytic boron nitride (pBN) and fused silica ampoules with the majority of the detached results occurring predictably in the pBN. The contact angles were 173 deg (Ge) and 165 deg (GeSi) for pBN. For fused silica, the contact angle decreases from 150 deg to an equilibrium value of 117 deg (Ge) or from 129 deg to an equilibrium value of 100 deg (GeSi) over the duration of the experiment. The nature and extent of detachment is determined by using profilometry in conjunction with optical and electron microscopy. The stability of detachment has been analyzed, and an empirical model for the conditions necessary to achieve sufficient stability to maintain detached growth for extended periods has been developed. Results in this presentation will show that we have established the effects on detachment of ampoule material, pressure difference above and below the melt, and silicon concentration; samples that are nearly completely detached can be grown repeatedly in pBN.

Experimental results from detached plasmas in TFTR

International Nuclear Information System (INIS)

Strachan, J.D.; Boody, F.P.; Bush, C.E.

1986-10-01

Detached plasmas are formed in TFTR which have the principal property of the boundary to the high temperature plasma core being defined by a radiating layer. This paper documents the properties of TFTR ohmic-detached plasmas with a range of plasma densities at two different plasma currents

Characterisation of detached plasmas on the MAST tokamak

Energy Technology Data Exchange (ETDEWEB)

Harrison, J.R., E-mail: james.harrison@ccfe.ac.uk [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Department of Physics, University of York, Heslington, York, YO10 5DD (United Kingdom); Lisgo, S.W. [ITER Organization, Route de Vinon-sur-Verdon, St.Paul-lez-Durance, Cedex (France); Gibson, K.J. [Department of Physics, University of York, Heslington, York, YO10 5DD (United Kingdom); Tamain, P. [CEA, IRFM, F-13108 Saint-Paul-lez-Durance (France); Dowling, J. [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom)

2011-08-01

Divertor detachment is an attractive operating regime for the next generation of tokamak devices, as it offers a means of mitigating the steady-state heat flux to plasma facing components. In order to clarify the dominant physical mechanisms that govern detachment, high quality data from several diagnostics are required to constrain theoretical models. To that end, high spatial ({approx}3 mm) and temporal (5 kHz) resolution measurements have been made of the intensity of deuterium Balmer and carbon emission lines during the onset and evolution of detachment of the lower inner strike point in MAST L-mode discharges. Furthermore, spatially-resolved measurements of the shapes and intensities of high-n Balmer lines have been recorded to infer plasma conditions during the detached phase.

Hypersonic Combustor Model Inlet CFD Simulations and Experimental Comparisons

Science.gov (United States)

Venkatapathy, E.; TokarcikPolsky, S.; Deiwert, G. S.; Edwards, Thomas A. (Technical Monitor)

1995-01-01

Numerous two-and three-dimensional computational simulations were performed for the inlet associated with the combustor model for the hypersonic propulsion experiment in the NASA Ames 16-Inch Shock Tunnel. The inlet was designed to produce a combustor-inlet flow that is nearly two-dimensional and of sufficient mass flow rate for large scale combustor testing. The three-dimensional simulations demonstrated that the inlet design met all the design objectives and that the inlet produced a very nearly two-dimensional combustor inflow profile. Numerous two-dimensional simulations were performed with various levels of approximations such as in the choice of chemical and physical models, as well as numerical approximations. Parametric studies were conducted to better understand and to characterize the inlet flow. Results from the two-and three-dimensional simulations were used to predict the mass flux entering the combustor and a mass flux correlation as a function of facility stagnation pressure was developed. Surface heat flux and pressure measurements were compared with the computed results and good agreement was found. The computational simulations helped determine the inlet low characteristics in the high enthalpy environment, the important parameters that affect the combustor-inlet flow, and the sensitivity of the inlet flow to various modeling assumptions.

[Preventive treatment of retinal detachment in aphakic eyes].

Science.gov (United States)

Regnault, F; Bregeat, P

1977-01-01

We have examined 243 cases with retinal detachment occurring within 6 months following cataract surgery. In 92 of them retinal tear was due to lattice degeneration, in 66 to snail track degeneration and in 17 to equatorial degeneration. 290 other patients had preventive treatments. In this group, there were only 10 cases of retinal detachment. 9 out of 22 patients who had no preventive treatment suffered retinal detachments. There are two reasons for the occurrence of this retinal detachment in the 6 months following cataract surgery in eyes where retinal degenerations are found: (1) surgical trauma even with cryoextraction is responsible for traction of the vitreous base, (2) rapid disappearance of the hyaluronic acid in the aphakic vitreous is responsible for the degradation of the vitreous with formation of large zones of liquid vitreous. When adhesion between the vitreous and the retinal degeneration area remains, the traction is responsible for retinal tear or retinal detachment. The importance of the preventive treatment of retinal lesions prior to cataract surgery should be stressed.

The fellow eye of patients with phakic rhegmatogenous retinal detachment from atrophic holes of lattice degeneration without posterior vitreous detachment.

Science.gov (United States)

Gonzales, C R; Gupta, A; Schwartz, S D; Kreiger, A E

2004-11-01

Primary phakic rhegmatogenous retinal detachment (RRD) without posterior vitreous detachment (PVD) represents a unique clinical entity that behaves differently from RRD associated with PVD. While previous studies have reported the long term findings in the fellow eye of patients with RRD and PVD, the outcome of the fellow eye of patients with RRD without PVD is not known. Consecutive patients with RRD not associated with PVD were studied retrospectively. The authors evaluated the fellow eye for retinal detachment or other vision threatening pathology. 27 patients (mean age 32 years) were studied with follow up of between 9 and 326 months (mean 111 months). 24 (89%) were myopic. Bilateral retinal detachment occurred in eight patients (30%). On initial examination, 17 patients (63%) had retinal findings (including lattice degeneration, atrophic holes, and/or cystic retinal tufts) in the fellow eye that might predispose them to retinal detachment. 14 vision threatening events or diagnoses occurred (nine of which were rhegmatogenous in nature) in the fellow eye including eight retinal detachments, one traumatic PVD without retinal tears, one retinal tear after PVD, one diagnosis of pigmentary glaucoma needing trabeculectomy, two visually significant cataracts, and one diagnosis of chorioretinitis. 23 patients (85%) maintained visual acuity better than 20/50, with most retaining 20/20 vision in the fellow eye. Patients who experience RRD without PVD are at risk of developing vision threatening events in the contralateral eye and, as such, the fellow eye should be followed carefully.

[Prevention of retinal detachment and treatment of retinoschisis].

Science.gov (United States)

Messmer, E P

1990-01-01

The necessity for prophylactic treatment for degenerative disease in the peripheral retina cannot be evaluated merely on the basis of the ophthalmoscopic findings. Factors such as the patient's history, refraction, the status of the vitreous, and prospective future cataract extraction all have a major impact on the risk of developing retinal detachment. The latter condition can be classified in to three groups: (1) low risk (patients with no history of retinal detachment, intraocular surgery or posterior vitreous detachment, myopia less than three diopters): treatment of atrophic holes and lattice degeneration is not justified, treatment of flap tears according to the circumstances; (2) medium risk (patients with no history of retinal or posterior vitreous detachment; however, myopia of more than three diopters and/or aphakia): the treatment of lattice degeneration is not justified; treatment of breaks according to the circumstances; (3) high risk: (patients with symptoms of posterior vitreous detachment): the treatment of lattice degeneration and atrophic holes is not justified: treatment of tears is necessary; fellow eyes: the treatment of retinal breaks is necessary; treatment of lattice degeneration seems advisable in cases with bilateral symmetric findings or prior to cataract extraction. Treatment of senile retinoschisis is only justified in cases with large and centrally located holes in the outer wall or in the presence of symptomatic schisis detachment.

Wave-driven fluxes through New River Inlet, NC

Science.gov (United States)

Wargula, A.; Raubenheimer, B.; Elgar, S.

2012-12-01

The importance of wave forcing to inlet circulation is examined using observations of waves, water levels, and currents collected in and near New River Inlet, NC during April and May, 2012. A boat-mounted system was used to measure current profiles along transects across the inlet mouth during three 14-hr periods, providing information on cross-inlet current structure, as well as discharge. Additionally, an array of 13 colocated pressure gages and profilers were deployed along 2 km of the inlet channel (5 to 10 m water depths) and ebb shoal channel (2 to 3 m water depths) and 19 colocated pressure gages and acoustic Doppler velocimeters were deployed across and offshore of the ebb shoal (1 to 5 m water depths) (Figure 1). The inlet is well mixed and tidal currents ranged from +/- 1.5 m/s, maximum discharge rates at peak ebb and flood were about 700 to 900 m3/s, offshore significant wave heights Hsig were 0.5 to 2.5 m, and wind speeds ranged from 0 to 14 m/s. Time-integrated residual discharge over semi-diurnal tidal cycles with similar ranges was ebb dominant during calm conditions (May 11, net out-of-inlet discharge ~ 55 m3, Hsig ~ 0.5 m, NW winds ~ 3 m/s) and flood dominant during stormier conditions (May 14, net into-inlet discharge ~ 15 m3, Hsig ~ 1.2 m, S winds ~ 6.5 m/s). Low-pass filtered in situ profiler data suggest wave-forcing affects the fluxes into and out of the inlet. The observations will be used to examine the momentum balance governing the temporal and cross-inlet (channel vs. shoal) variation of these fluxes, as well as the effect of waves on ebb and flood flow dominance. Funding provided by the Office of Naval Research and a National Security Science and Engineering Faculty Fellowship.; Figure 1: Google Earth image of New River Inlet, NC. Colors are depth contours (scale on the right, units are m relative to mean sea level) and symbols are locations of colocated current meters and pressure gages.

Kinematic evidence for downdip movement on the Mormon Peak detachment

Science.gov (United States)

Walker, Christopher D.; Anders, Mark H.; Christie-Blick, Nicholas

2007-03-01

The Mormon Peak detachment is considered to be one of the best examples of a rooted upper crustal detachment fault that propagated through the brittle crust at a low angle. The hanging wall of the detachment today consists of a number of isolated blocks that have been interpreted as remnants of a once-contiguous extensional allochthon. Here we present the results of a new study of directional indicators from the basal surfaces beneath these blocks. These measurements do not agree with the long-standing interpretation of a S75°W movement direction for the detachment hanging wall. Instead, the most recent movement on each section of the detachment took place approximately parallel to the present downdip direction. We conclude that the Mormon Peak detachment is best explained as the basal surfaces to a series of rootless gravity slides.

Unstart Coupling Mechanism Analysis of Multiple-Modules Hypersonic Inlet

Directory of Open Access Journals (Sweden)

Jichao Hu

2013-01-01

Full Text Available The combination of multiplemodules in parallel manner is an important way to achieve the much higher thrust of scramjet engine. For the multiple-modules scramjet engine, when inlet unstarted oscillatory flow appears in a single-module engine due to high backpressure, how to interact with each module by massflow spillage, and whether inlet unstart occurs in other modules are important issues. The unstarted flowfield and coupling characteristic for a three-module hypersonic inlet caused by center module II and side module III were, conducted respectively. The results indicate that the other two hypersonic inlets are forced into unstarted flow when unstarted phenomenon appears on a single-module hypersonic inlet due to high backpressure, and the reversed flow in the isolator dominates the formation, expansion, shrinkage, and disappearance of the vortexes, and thus, it is the major factor of unstart coupling of multiple-modules hypersonic inlet. The coupling effect among multiple modules makes hypersonic inlet be more likely unstarted.

Unstart coupling mechanism analysis of multiple-modules hypersonic inlet.

Science.gov (United States)

Hu, Jichao; Chang, Juntao; Wang, Lei; Cao, Shibin; Bao, Wen

2013-01-01

The combination of multiplemodules in parallel manner is an important way to achieve the much higher thrust of scramjet engine. For the multiple-modules scramjet engine, when inlet unstarted oscillatory flow appears in a single-module engine due to high backpressure, how to interact with each module by massflow spillage, and whether inlet unstart occurs in other modules are important issues. The unstarted flowfield and coupling characteristic for a three-module hypersonic inlet caused by center module II and side module III were, conducted respectively. The results indicate that the other two hypersonic inlets are forced into unstarted flow when unstarted phenomenon appears on a single-module hypersonic inlet due to high backpressure, and the reversed flow in the isolator dominates the formation, expansion, shrinkage, and disappearance of the vortexes, and thus, it is the major factor of unstart coupling of multiple-modules hypersonic inlet. The coupling effect among multiple modules makes hypersonic inlet be more likely unstarted.

Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment

Directory of Open Access Journals (Sweden)

L. Sh. Bilandarli

2017-01-01

Full Text Available Review describes the theme of rhegmatogenous retinal dеtаchment associated with choroidal separation. It is rare, but quite severe eye pathology. In most cases it has a very poor prognosis. Most authors consider the retinal detachment as a primary pathogenetic part, which decompensates the production of aqueous humor by increasing the absorptive surface of the retinal pigment epithelium. Dilatation of choroidal arterioles occurs in hypotension, it leads to extravasation of protein-rich fluid in the choroidal and the suprachoroidal space. This helps to further swelling and separation of the ciliary body and the choroid with reduced production of aqueous humor and progressive hypotension. There is a high risk of developing “retino-choroidal” separation in patients with macular rupture due to localization of retinal separation and rupture rear hyaloid membrane. The protein level in aqueous humor can be increased to 70 times. It may be a result of reflux of suprachoroidal proteins through uveoscleral route and / or venous proteins through the trabecular network. In addition, the diffusion of proteins from the posterior camera and vitreous cavity is possible. This creates favorable conditions for cell proliferation that can lead to postoperative proliferative vitreoretinopathy. Typically patients have a pronounced signs of inflammation, pain, and “red eye”, which is accompanied with vision decrement. Rhegmatogenous retinal reparationcan be associated with such clinical symptoms as severe panuveit, deepening of the anterior camera and the inflammatory response in the moisture, concentric wrinkles and sagging back of the iris, posterior synechia, iridofakodenez, blurred vitreous detachment of the ciliary body, hypotension, and choroidal and retinal detachment in addition. Debatableness of etiopathogenesis and a clinical picture, which is similar to other eye diseases create significant difficulties in early diagnosis and proper treatment of

CFD Models of a Serpentine Inlet, Fan, and Nozzle

Science.gov (United States)

Chima, R. V.; Arend, D. J.; Castner, R. S.; Slater, J. W.; Truax, P. P.

2010-01-01

Several computational fluid dynamics (CFD) codes were used to analyze the Versatile Integrated Inlet Propulsion Aerodynamics Rig (VIIPAR) located at NASA Glenn Research Center. The rig consists of a serpentine inlet, a rake assembly, inlet guide vanes, a 12-in. diameter tip-turbine driven fan stage, exit rakes or probes, and an exhaust nozzle with a translating centerbody. The analyses were done to develop computational capabilities for modeling inlet/fan interaction and to help interpret experimental data. Three-dimensional Reynolds averaged Navier-Stokes (RANS) calculations of the fan stage were used to predict the operating line of the stage, the effects of leakage from the turbine stream, and the effects of inlet guide vane (IGV) setting angle. Coupled axisymmetric calculations of a bellmouth, fan, and nozzle were used to develop techniques for coupling codes together and to investigate possible effects of the nozzle on the fan. RANS calculations of the serpentine inlet were coupled to Euler calculations of the fan to investigate the complete inlet/fan system. Computed wall static pressures along the inlet centerline agreed reasonably well with experimental data but computed total pressures at the aerodynamic interface plane (AIP) showed significant differences from the data. Inlet distortion was shown to reduce the fan corrected flow and pressure ratio, and was not completely eliminated by passage through the fan

Brazos Santiago Inlet, Texas, Shoaling Study

Science.gov (United States)

2018-02-01

Development Center 3909 Halls Ferry Road Vicksburg, MS 39180-6199 Final report Approved for public release; distribution is unlimited. Prepared...focus of this study was to understand the shoaling process in the BSI and to suggest sand management alternatives to reduce inlet maintenance ...Santiago Inlet Entrance Channel maintenance dredging quantities (normal distribution). ........................................................ 20

Method of detaching adherent cells for flow cytometry

KAUST Repository

Kaur, Mandeep

2015-12-24

In one aspect, a method for detaching adherent cells can include adding a cell lifting solution to the media including a sample of adherent cells and incubating the sample of adherent cells with the cell lifting solution. No scraping or pipetting is needed to facilitate cell detachment. The method do not require inactivation of cell lifting solution and no washing of detaching cells is required to remove cell lifting solution. Detached cells can be stained with dye in the presence of cell lifting solution and are further analyzed using flow cytometer. The method has been tested using 6 different cell lines, 4 different assays, two different plate formats (96 and 384 well plates) and two different flow cytometry instruments. The method is simple to perform, less time consuming, with no cell loss and makes high throughput flow cytometry on adherent cells a reality.

Inlet Trade Study for a Low-Boom Aircraft Demonstrator

Science.gov (United States)

Heath, Christopher M.; Slater, John W.; Rallabhandi, Sriram K.

2016-01-01

Propulsion integration for low-boom supersonic aircraft requires careful inlet selection, placement, and tailoring to achieve acceptable propulsive and aerodynamic performance, without compromising vehicle sonic boom loudness levels. In this investigation, an inward-turning streamline-traced and axisymmetric spike inlet are designed and independently installed on a conceptual low-boom supersonic demonstrator aircraft. The airframe was pre-shaped to achieve a target ground under-track loudness of 76.4 PLdB at cruise using an adjoint-based design optimization process. Aircraft and inlet performance characteristics were obtained by solution of the steady-state Reynolds-averaged Navier-Stokes equations. Isolated cruise inlet performance including total pressure recovery and distortion were computed and compared against installed inlet performance metrics. Evaluation of vehicle near-field pressure signatures, along with under- and off-track propagated loudness levels is also reported. Results indicate the integrated axisymmetric spike design offers higher inlet pressure recovery, lower fan distortion, and reduced sonic boom. The vehicle with streamline-traced inlet exhibits lower external wave drag, which translates to a higher lift-to-drag ratio and increased range capability.

HAMLET binding to α-actinin facilitates tumor cell detachment.

Science.gov (United States)

Trulsson, Maria; Yu, Hao; Gisselsson, Lennart; Chao, Yinxia; Urbano, Alexander; Aits, Sonja; Mossberg, Ann-Kristin; Svanborg, Catharina

2011-03-08

Cell adhesion is tightly regulated by specific molecular interactions and detachment from the extracellular matrix modifies proliferation and survival. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a protein-lipid complex with tumoricidal activity that also triggers tumor cell detachment in vitro and in vivo, suggesting that molecular interactions defining detachment are perturbed in cancer cells. To identify such interactions, cell membrane extracts were used in Far-western blots and HAMLET was shown to bind α-actinins; major F-actin cross-linking proteins and focal adhesion constituents. Synthetic peptide mapping revealed that HAMLET binds to the N-terminal actin-binding domain as well as the integrin-binding domain of α-actinin-4. By co-immunoprecipitation of extracts from HAMLET-treated cancer cells, an interaction with α-actinin-1 and -4 was observed. Inhibition of α-actinin-1 and α-actinin-4 expression by siRNA transfection increased detachment, while α-actinin-4-GFP over-expression significantly delayed rounding up and detachment of tumor cells in response to HAMLET. In response to HAMLET, adherent tumor cells rounded up and detached, suggesting a loss of the actin cytoskeletal organization. These changes were accompanied by a reduction in β1 integrin staining and a decrease in FAK and ERK1/2 phosphorylation, consistent with a disruption of integrin-dependent cell adhesion signaling. Detachment per se did not increase cell death during the 22 hour experimental period, regardless of α-actinin-4 and α-actinin-1 expression levels but adherent cells with low α-actinin levels showed increased death in response to HAMLET. The results suggest that the interaction between HAMLET and α-actinins promotes tumor cell detachment. As α-actinins also associate with signaling molecules, cytoplasmic domains of transmembrane receptors and ion channels, additional α-actinin-dependent mechanisms are discussed.

Structural recovery of the detached macula after retinal detachment repair as assessed by optical coherence tomography.

Science.gov (United States)

Joe, Soo Geun; Kim, Yoon Jeon; Chae, Ju Byung; Yang, Sung Jae; Lee, Joo Yong; Kim, June-Gone; Yoon, Young Hee

2013-06-01

To investigate correlations between preoperative and postoperative foveal microstructures in patients with macula-off rhegmatogenous retinal detachment (RRD). We reviewed the records of 31 eyes from 31 patients with macula-off RRD who had undergone successful re-attachment surgery. We analyzed data obtained from complete ophthalmologic examinations and optical coherence tomography (OCT) before and 9 to 12 months after surgery. All postoperative OCT measurements were taken with spectral-domain OCT, but a subset of preoperative OCT measurements were taken with time-domain OCT. The mean duration of macular detachment was 15.5 ± 15.2 days, and mean preoperative best-corrected visual acuity (BCVA, logarithm of the minimum angle of resolution) was 1.03 ± 0.68. Preoperative visual acuity was correlated with retinal detachment height (p macula-off duration. The final BCVA was significantly correlated with integrity of the junction between the photoreceptor inner and outer segments (IS/OS) combined with the continuity of external limiting membrane (ELM) (p = 0.025). The presence of IRS and OLU on a detached macula were highly correlated with the final postoperative integrity of the IS/OS junction and the ELM (p = 0.017). Eyes preoperatively exhibiting IRS and OLU showed a higher incidence of disruption to the photoreceptor IS/OS junction and the ELM at final follow-up. Such a close correlation between preoperative and postoperative structural changes may explain why ultimate visual recovery in such eyes is poor.

Negative ion detachment processes

International Nuclear Information System (INIS)

Champion, R.L.; Doverspike, L.D.

1990-10-01

This paper discusses the following topics: H - and D - collisions with atomic hydrogen; collisional decomposition of SF 6 - ; two-electron loss processes in negative ion collisions; associative electron detachment; and negative ion desorption from surfaces

Exudative Retinal Detachment Treatment in a Patient with Thrombotic Thrombocytopenic Purpura

Directory of Open Access Journals (Sweden)

Magali Sampo

2016-02-01

Full Text Available Purpose: We report a case of unilateral exudative retinal detachment in a patient with thrombotic thrombocytopenic purpura (TTP, without associated hypertension, successfully treated with plasmapheresis. Case Report: A 46-year-old woman with a medical history of TTP presented with unilateral exudative retinal detachment. Biological and radiological assessment eliminated other causes of exudative retinal detachment, including hypertension. Plasma exchange was performed, followed by a rapid improvement in visual acuity and total disappearance of serous detachment. Conclusion: Exudative unilateral retinal detachment is a rare complication of TTP and can be successfully treated by plasma exchange.

[Stickler's syndrome (dystrophia vitreoretinalis hereditaria). Results of surgery for retinal detachment].

Science.gov (United States)

Karel, I; Dolezalová, J; Oudová, P

2001-05-01

Stickler's syndrome (SS) is an autosomal dominant hereditary disease of the collagenous connective tissue where impaired development of the vitreous body gel and peripheral retina and detachment of the retina are associated with general manifestations. The objective of the retrospective study was to evaluate the long-term results of surgery of retinal detachment in SS. The group of patients comprised 7 patients, 6 men and 1 woman aged 4 to 45 years, average age 16.8 years. Autosomal dominant heredity was obvious in 6 members (85.7%) of two families. General manifestations of SS included abnormalities of the facial skeleton (6 patients), cleft palate (4 patients), impaired hearing (2 patients), marfanoid habitus (2 patients) and hyperextensibility of the joints (4 patients). In the eyes with SS was manifested by myopia from -1 to -9 D and a liquid vitreous body. Multiple foci of lattice degeneration supplemented the finding in 6 patients (85.7%). Detachment of the retina was a manifestation of SS in 12 of 14 eyes (85.7%). It was manifested in 5 of 7 patients concurrently or within 12 years in both eyes. The causes of retinal detachment were multiple equatorial and postequatorial tears due to lattice degeneration in 8 eyes (66.7%) or a giant tear in 4 eyes (33.3%). Advanced proliferative vitreoretinopathy (PVR) was associated with retinal detachment in 8 eyes (66.7%) and in 6 eyes (50%) it was not possible to assess the beginning of retinal detachment. In 3 of 5 patients with bilateral retinal detachment the adverse course of retinal detachment on the first eye was followed 8 to 12 years previously in another department: two retinal detachments with giant tears were evaluated as inoperable and one inveterated detachment with advanced PVR was operated unsuccessfully. Retinal detachment was operated in 9 eyes of 7 patients, in two patients both eyes were operated simultaneously. The patients were followed up after surgery for 11 months to 15 years, on average for 65

DETACHMENT OF HUMAN FIBROBLASTS FROM FEP-TEFLON SURFACES

NARCIS (Netherlands)

VANKOOTEN, TG; SCHAKENRAAD, JM; VANDERMEI, HC; BUSSCHER, HJ

1991-01-01

In this study a comparison is made between the detachment behavior of human fibroblasts adhered to hydrophobic FEP-Teflon (water contact angle 109 degrees) and to hydrophilic glass (water contact angle smaller than 15 degrees) during exposure to a laminar, incrementally loaded flow. Detachment from

Reconstruction of core inlet temperature distribution by cold leg temperature measurements

International Nuclear Information System (INIS)

Saarinen, S.; Antila, M.

2010-01-01

The reduced core of Loviisa NPP contains 33 thermocouple measurements measuring the core inlet temperature. Currently, these thermocouple measurements are not used in determining the inlet temperature distribution. The average of cold leg temperature measurements is used as inlet temperature for each fuel assembly. In practice, the inlet temperature distribution is not constant. Thus, using a constant inlet temperature distribution induces asymmetries in the measured core power distribution. Using a more realistic inlet temperature distribution would help us to reduce virtual asymmetries of the core power distribution and increase the thermal margins of the core. The thermocouples at the inlet cannot be used directly to measure the inlet temperature accurately because the calibration of the thermocouples that is done at hot zero power conditions is no longer valid at full power, when there is temperature change across the core region. This is due to the effect of neutron irradiation on the Seebeck coefficient of the thermocouple wires. Therefore, we investigate in this paper a method to determine the inlet temperature distribution based on the cold leg temperature measurements. With this method we rely on the assumption that although the core inlet thermocouple measurements do not measure the absolute temperature accurately they do measure temperature changes with sufficient accuracy particularly in big disturbances. During the yearly testing of steam generator safety valves we observe a large temperature increase up to 12 degrees in the cold leg temperature. The change in the temperature of one of the cold legs causes a local disturbance in the core inlet temperature distribution. Using the temperature changes observed in the inlet thermocouple measurements we are able to fit six core inlet temperature response functions, one for each cold leg. The value of a function at an assembly inlet is determined only by the corresponding cold leg temperature disturbance

Experimental Investigation of a Large-Scale Low-Boom Inlet Concept

Science.gov (United States)

Hirt, Stefanie M.; Chima, Rodrick V.; Vyas, Manan A.; Wayman, Thomas R.; Conners, Timothy R.; Reger, Robert W.

2011-01-01

A large-scale low-boom inlet concept was tested in the NASA Glenn Research Center 8- x 6- foot Supersonic Wind Tunnel. The purpose of this test was to assess inlet performance, stability and operability at various Mach numbers and angles of attack. During this effort, two models were tested: a dual stream inlet designed to mimic potential aircraft flight hardware integrating a high-flow bypass stream; and a single stream inlet designed to study a configuration with a zero-degree external cowl angle and to permit surface visualization of the vortex generator flow on the internal centerbody surface. During the course of the test, the low-boom inlet concept was demonstrated to have high recovery, excellent buzz margin, and high operability. This paper will provide an overview of the setup, show a brief comparison of the dual stream and single stream inlet results, and examine the dual stream inlet characteristics.

Detachments in Shale: Controlling Characteristics on Fold-Thrust Belt Style

Science.gov (United States)

Hansberry, Rowan; King, Ros; Collins, Alan; Morley, Chris

2013-04-01

Fold-thrust belts occur across multiple tectonic settings where thin-skinned deformation is accommodated by one or more detachment zones, both basal and within the fold-thrust belt. These fold-thrust belts exhibit considerable variation in structural style and vergence depending on the characteristics (e.g. strength, thickness, and lithology) and number of detachment zones. Shale as a detachment lithology is intrinsically weaker than more competent silts and sands; however, it can be further weakened by high pore pressures, reducing resistance to sliding and; high temperatures, altering the rheology of the detachment. Despite the implications for petroleum exploration and natural hazard assessment the precise nature by which detachments in shale control and are involved in deformation in fold-thrust belts is poorly understood. Present-day active basal detachment zones are usually located in inaccessible submarine regions. Therefore, this project employs field observations and sample analysis of ancient, exhumed analogues to document the nature of shale detachments (e.g. thickness, lithology, dip and dip direction, deformational temperature and thrust propagation rates) at field sites in Thailand, Norway and New Zealand. X-ray diffraction analysis of illite crystallinity and oxygen stable isotopes analysis are used as a proxy for deformational temperature whilst electron-backscatter diffraction analysis is used to constrain microstructural deformational patterns. K-Ar dating of synkinematic clay fault gouges is being applied to date the final stages of activity on individual faults with a view to constraining thrust activation sequences. It is not possible to directly measure palaeo-data for some key detachment parameters, such as pore pressure and coefficients of friction. However, the use of critical taper wedge theory has been used to successfully infer internal and basal coefficients of friction and depth-normalized pore pressure within a wedge and at its base

[Paediatric retinal detachment and hereditary vitreoretinal disorders].

Science.gov (United States)

Meier, P

2013-09-01

The number of retinal detachments in children is very low in comparison to the number in adults. One predisposing factor for development of paediatric retinal detachment is suffering from hereditary vitreoretinal degeneration (e.g., Stickler syndrome, Wagner syndrome, Kniest dysplasia, familial exudative vitreoretinopathy, congenital X-linked retinoschisis, Knobloch syndrome, incontinentia pigmenti, Norrie disease). Hereditary vitreoretinopathies are characterised by an abnormal-appearing vitreous gel with associated retinal changes. In most of these eyes further ocular abnormalities can be diagnosed. A group of hereditary disorders is associated with characteristic systemic abnormalities. Allied conditions should be considered in the clinical diagnosis. Vitreoretinopathies are the most common cause of inherited retinal detachment. In most eyes primary vitrectomy is necessary, and disease-specific surgical treatment is discussed. Georg Thieme Verlag KG Stuttgart · New York.

Cell detachment method using shock wave induced cavitation

NARCIS (Netherlands)

Junge, L.; Junge, L.; Ohl, C.D.; Wolfrum, B.; Arora, M.; Ikink, R.

2003-01-01

The detachment of adherent HeLa cells from a substrate after the interaction with a shock wave is analyzed. Cavitation bubbles are formed in the trailing, negative pressure cycle following the shock front. We find that the regions of cell detachment are strongly correlated with spatial presence of

Cup detachment during vacuum-assisted vaginal delivery and birth outcome.

Science.gov (United States)

Krispin, Eyal; Aviram, Amir; Salman, Lina; Chen, Rony; Wiznitzer, Arnon; Gabbay-Benziv, Rinat

2017-11-01

To determine the perinatal outcome associated with cup detachment during vacuum-assisted vaginal delivery (VAVD). A retrospective cohort study of all women attempting VAVD in a tertiary hospital (2012-2014). Singleton-term pregnancies were included. Antepartum fetal death and major fetal structural or chromosomal abnormalities were excluded. Primary outcome was neonatal birth trauma (subgaleal hematoma, subarachnoid hematoma, subdural hematoma, skull fracture, and/or erb's palsy). Secondary outcomes were maternal complications or other neonatal morbidities. Outcomes were compared between women after ≥1 cup detachment (study group) and the rest (control group). Logistic regression analysis was utilized to adjust results to potential confounders. Overall, 1779 women attempted VAVD during study period. Of them, in 146 (8.2%), the cup detached prior to delivery; 130/146 (89%) had a single detachment. After detachment, 4 (2.7%) delivered by cesarean section, 77 (52.7%) delivered after cup reapplication, and 65 (44.6%) delivered spontaneously. Women in the study group were more likely to undergo VAVD due to prolonged second stage, and were characterized by lower rates of metal cup use. Neonates in the detachment group had higher rates of subarachnoid hematoma and composite neonatal birth trauma (2.7 vs. 0.1% and 4.8 vs. 1.8%, respectively, p Cup detachment is associated with a higher rate of adverse neonatal outcome. Cup reapplication should be considered carefully.

Flow Simulation of Supersonic Inlet with Bypass Annular Duct

Science.gov (United States)

Kim, HyoungJin; Kumano, Takayasu; Liou, Meng-Sing; Povinelli, Louis A.; Conners, Timothy R.

2011-01-01

A relaxed isentropic compression supersonic inlet is a new concept that produces smaller cowl drag than a conventional inlet, but incurs lower total pressure recovery and increased flow distortion in the (radially) outer flowpath. A supersonic inlet comprising a bypass annulus to the relaxed isentropic compression inlet dumps out airflow of low quality through the bypass duct. A reliable computational fluid dynamics solution can provide considerable useful information to ascertain quantitatively relative merits of the concept, and further provide a basis for optimizing the design. For a fast and reliable performance evaluation of the inlet performance, an equivalent axisymmetric model whose area changes accounts for geometric and physical (blockage) effects resulting from the original complex three-dimensional configuration is proposed. In addition, full three-dimensional calculations are conducted for studying flow phenomena and verifying the validity of the equivalent model. The inlet-engine coupling is carried out by embedding numerical propulsion system simulation engine data into the flow solver for interactive boundary conditions at the engine fan face and exhaust plane. It was found that the blockage resulting from complex three-dimensional geometries in the bypass duct causes significant degradation of inlet performance by pushing the terminal normal shock upstream.

Inlet effects on vertical-downward air–water two-phase flow

Energy Technology Data Exchange (ETDEWEB)

Qiao, Shouxu; Mena, Daniel; Kim, Seungjin, E-mail: skim@psu.edu

2017-02-15

Highlights: • Inlet effects on two-phase flow parameters in vertical-downward flow are studied. • Flow regimes in the vertical-downward two-phase flow are defined. • Vertical-downward flow regime maps for three inlet configurations are developed. • Frictional pressure loss analysis for three different inlets is performed. • Database of local two-phase flow parameters for each inlet configuration. - Abstract: This paper focuses on investigating the geometric effects of inlets on global and local two-phase flow parameters in vertical-downward air–water two-phase flow. Flow visualization, frictional pressure loss analysis, and local experiments are performed in a test facility constructed from 50.8 mm inner diameter acrylic pipes. Three types of inlets of interest are studied: (1) two-phase flow injector without a flow straightener (Type A), (2) two-phase flow injector with a flow straightener (Type B), and (3) injection through a horizontal-to-vertical-downward 90° vertical elbow (Type C). A detailed flow visualization study is performed to characterize flow regimes including bubbly, slug, churn-turbulent, and annular flow. Flow regime maps for each inlet are developed and compared to identify the effects of each inlet. Frictional pressure loss analysis shows that the Lockhart–Martinelli method is capable of correlating the frictional loss data acquired for Type B and Type C inlets with a coefficient value of C = 25, but additional data may be needed to model the Type A inlet. Local two-phase flow parameters measured by a four-sensor conductivity probe in four bubbly and near bubbly flow conditions are analyzed. It is observed that vertical-downward two-phase flow has a characteristic center-peaked void profile as opposed to a wall-peaked profile as seen in vertical-upward flow. Furthermore, it is shown that the Type A inlet results in the most pronounced center-peaked void fraction profile, due to the coring phenomenon. Type B and Type C inlets

Numerical modeling of turbulent swirling flow in a multi-inlet vortex nanoprecipitation reactor using dynamic DDES

Science.gov (United States)

Hill, James C.; Liu, Zhenping; Fox, Rodney O.; Passalacqua, Alberto; Olsen, Michael G.

2015-11-01

The multi-inlet vortex reactor (MIVR) has been developed to provide a platform for rapid mixing in the application of flash nanoprecipitation (FNP) for manufacturing functional nanoparticles. Unfortunately, commonly used RANS methods are unable to accurately model this complex swirling flow. Large eddy simulations have also been problematic, as expensive fine grids to accurately model the flow are required. These dilemmas led to the strategy of applying a Delayed Detached Eddy Simulation (DDES) method to the vortex reactor. In the current work, the turbulent swirling flow inside a scaled-up MIVR has been investigated by using a dynamic DDES model. In the DDES model, the eddy viscosity has a form similar to the Smagorinsky sub-grid viscosity in LES and allows the implementation of a dynamic procedure to determine its coefficient. The complex recirculating back flow near the reactor center has been successfully captured by using this dynamic DDES model. Moreover, the simulation results are found to agree with experimental data for mean velocity and Reynolds stresses.

Coolant inlet device for nuclear reactors

International Nuclear Information System (INIS)

Ando, Hiroshi; Abe, Yasuhiro; Iwabuchi, Toshihiko; Yamamoto, Kenji.

1969-01-01

Herein disclosed is a coolant inlet device for liquid-metal cooled reactors which employs a coolant distributor serving also as a supporting means for the reactor core. The distributor is mounted within the reactor vessel so as to slide horizontally on supporting lugs, and is further slidably connected via a junction pipe to a coolant inlet conduit protruding through the floor of the vessel. The distributor is adapted to uniformly disperse the highly pressured coolant over the reactor core so as to reduce the stresses sustained by the reactor vessel as well as the supporting lugs. Moreover, the slidable nature of the distributor allows thermal shock and excessive coolant pressures to be prevented or alleviated, factors which posed major difficulties in conventional coolant inlet devices. (Owens, K. J.)

An Investigation of the Drag and Pressure Recovery of a Submerged Inlet and a Nose Inlet in the Transonic Flight Range with Free-fall Models

Science.gov (United States)

Selna, James; Schlaff, Bernard A

1951-01-01

The drag and pressure recovery of an NACA submerged-inlet model and an NACA series I nose-inlet model were investigated in the transonic flight range. The tests were conducted over a mass-flow-ratio range of 0.4 to 0.8 and a Mach number range of about 0.8 to 1.10 employing large-scale recoverable free-fall models. The results indicate that the Mach number of drag divergence of the inlet models was about the same as that of a basic model without inlets. The external drag coefficients of the nose-inlet model were less than those of the submerged-inlet model throughout the test range. The difference in drag coefficient based on the maximum cross-sectional area of the models was about 0.02 at supersonic speeds and about 0.015 at subsonic speeds. For a hypothetical airplane with a ratio of maximum fuselage cross-sectional area to wing area of 0.06, the difference in airplane drag coefficient would be relatively small, about 0.0012 at supersonic speeds and about 0.0009 at subsonic speeds. Additional drag comparisons between the two inlet models are made considering inlet incremental and additive drag.

Numerical analysis of the bubble detachment diameter in nucleate boiling

International Nuclear Information System (INIS)

Lamas, M I; Sáiz Jabardo, J M; Arce, A; Fariñas, P

2012-01-01

The present paper presents a tri-dimensional CFD (Computational Fluid Dynamics) model to investigate the fluid flow around bubbles attached to heated walls. Transient solutions of the governing field equations in a domain containing the bubbles and the surrounding liquid have been obtained. The nucleation, growing and detachment processes have been analyzed. Concerning the software, the open source OpenFOAM has been used. Special attention has been given to the bubble detachment diameter. Two mechanisms have been considered as physically related to the detachment: surface tension and buoyancy. As expected, it has been verified that the bubble detachment diameter depends on the contact angle, operating pressure and properties of the fluid. Several fluids have been considered (water, R134a, ammonia and R123), as well as several operating pressures (between 0.1 and 10 bar) and contact angles (between 10 and 80°). It has been concluded that the detachment diameter depends strongly on the contact angle and fluid properties and slightly on the pressure. A correlation for the bubble detachment diameter has been developed based on the obtained numerical results. Data from this expression compare reasonably well with those from other correlations from the literature.

Design of the Detachable Extension Shaft Assembly for KJRR

International Nuclear Information System (INIS)

Lee, Jin Haeng; Yoo, Yeon-Sik; Cho, Yeong-Garp; Ryou, Myoung-Han; Ryu, Jeong-Soo

2015-01-01

In this study, we designed the ESA and basket which can increase the connecting force between the ES adapter and the ES, and can be easily attachable and detachable with the basket. Because the upper part of the ESA can be placed near the reactor core for a long time and directly connected to the FFA, the deterioration of its mechanical properties is expected to be relatively quicker than the lower part of the ESA. The ESA is therefore composed of an Extension Shaft (ES) and an ES adapter, and the ES adapter can be detachable from the ES and replaceable by new one. In the previous design concept, the ES adapter had four latches which can be detached from the ES in the reactor core by external pulling force, and the detached CAR or SSR, FFA and ES adapter are individually disconnected in some baskets when it is needed to replace CAR/SSR/FFA or shuffle them. When the force is too small, the bundle of CAR/SSR/FFA and ES adapter can be unexpectedly detached from the ES. To solve the problem, we have studied another design concept which can increase the connecting force and can be easily detachable when it is needed. The forces needed to be connected and disconnected were calculated from FE analysis, and the force to be disconnected can be guessed without FE contact analysis. The prototypes of the designed components were fabricated, and they were suitable to be used

Oregon inlet: Hydrodynamics, volumetric flux and implications for larval fish transport

Energy Technology Data Exchange (ETDEWEB)

Nichols, C.R. [National Oceanic and Atmospheric Administration, Silver Springs, MD (United States); Pietrafesa, L.J. [North Carolina State Univ., Raleigh, NC (United States). Department of Marine, Earth and Atmospheric Sciences

1997-05-01

The temporal response of Oregon Inlet currents to atmospheric forcing and sea level fluctuations is analyzed using time and frequency domain analysis. Temporally persistent and spatially extensive ebb and flood events are identified using data sets from both within and outside of Oregon Inlet. Prism estimates are made to generate a time series of volumetric flux of water transported through the inlet. Water masses flooding into the Pamlico Sound via Oregon Inlet are identified in temperature (T) and salinity (S) space to determine their source of origin. Correlations are examined between the atmospheric wind field, the main axial slope of the inlet`s water level, inlet flow and T, S properties. Synoptic scale atmospheric wind events are found to dramatically and directly affect the transport of water towards (away from) the inlet on the ocean side, in concert with the contemporaneous transport away from (towards) the inlet on the estuary side, and a subsequent flooding into (out of) the estuary via Oregon Inlet. Thus, while astronomical tidal flooding and ebbing events are shown to be one-sided as coastal waters either set-up or set-down, synoptic scale wind events are shown to be manifested as a two-sided in-phase response set-up and set-down inside and outside the inlet, and thus are extremely effective in driving currents through the inlet. These subinertial frequency flood events are believed to be essential for both the recruitment and subsequent retention of estuarine dependent larval fish from the coastal ocean into Pamlico Sound. Year class strength of these finish may be determined annually by the relative strength and timing of these climatological wind events.

Bilateral Rhegmatogenous Retinal Detachment during External Beam Radiotherapy

Directory of Open Access Journals (Sweden)

Takako Hidaka

2016-06-01

Full Text Available Herein, we report a case of nontraumatic bilateral rhegmatogenous retinal detachment (RRD during external beam radiotherapy for nonocular tumor, presented as an observational case study in conjunction with a review of the relevant literature. A 65-year-old male was referred to our hospital due to bilateral RRD. He underwent a biopsy for a tumor of the left frontal lobe 4 months prior to presentation, and the tumor had been diagnosed as primary central nerve system B-cell type lymphoma. He received chemotherapy and external beam radiotherapy for 1 month. There were no traumatic episodes. Bilateral retinal detachment occurred during a series of radiotherapies. Simultaneous nontraumatic bilateral retinal detachment is rare. The effects of radiotherapy on ocular functionality, particularly in cases involving retinal adhesion and vitreous contraction, may include RRD. Thus, it is necessary to closely monitor the eyes of patients undergoing radiotherapy, particularly those undergoing surgery for retinal detachment and those with a history of photocoagulation for retinal tears, a relevant family history, or risk factors known to be associated with RRD.

Status of the variable diameter centerbody inlet program

Science.gov (United States)

Saunders, John D.; Linne, A. A.

1992-01-01

The Variable Diameter Centerbody (VDC) inlet is an ongoing research program at LeRC. The VDC inlet is a mixed compression, axisymmetric inlet that has potential application on the next generation supersonic transport. This inlet was identified as one of the most promising axisymmetric concepts for supersonic cruise aircraft during the SCAR program in the late 1970's. Some of its features include high recovery, low bleed, good angle-of-attack tolerance, and excellent engine airflow matching. These features were demonstrated at LeRC in the past by the design and testing of fixed hardware models. A current test program in the LeRC 10' x 10' Supersonic Wind Tunnel (SWT) will attempt to duplicate these features on model hardware that actually incorporates a flight-like variable diameter centerbody mechanism.

A Meta-Analysis on Antecedents and Outcomes of Detachment from Work.

Science.gov (United States)

Wendsche, Johannes; Lohmann-Haislah, Andrea

2016-01-01

Detachment from work has been proposed as an important non-work experience helping employees to recover from work demands. This meta-analysis (86 publications, k = 91 independent study samples, N = 38,124 employees) examined core antecedents and outcomes of detachment in employee samples. With regard to outcomes, results indicated average positive correlations between detachment and self-reported mental (i.e., less exhaustion, higher life satisfaction, more well-being, better sleep) and physical (i.e., lower physical discomfort) health, state well-being (i.e., less fatigue, higher positive affect, more intensive state of recovery), and task performance (small to medium sized effects). However, average relationships between detachment and physiological stress indicators and work motivation were not significant while associations with contextual performance and creativity were significant, but negative. Concerning work characteristics, as expected, job demands were negatively related and job resources were positively related to detachment (small sized effects). Further, analyses revealed that person characteristics such as negative affectivity/neuroticism (small sized effect) and heavy work investment (medium sized effect) were negatively related to detachment whereas detachment and demographic variables (i.e., age and gender) were not related. Moreover, we found a medium sized average negative relationship between engagement in work-related activities during non-work time and detachment. For most of the examined relationships heterogeneity of effect sizes was moderate to high. We identified study design, samples' gender distribution, and affective valence of work-related thoughts as moderators for some of these aforementioned relationships. The results of this meta-analysis point to detachment as a non-work (recovery) experience that is influenced by work-related and personal characteristics which in turn is relevant for a range of employee outcomes.

Cellular volume regulation and substrate stiffness modulate the detachment dynamics of adherent cells

Science.gov (United States)

Yang, Yuehua; Jiang, Hongyuan

2018-03-01

Quantitative characterizations of cell detachment are vital for understanding the fundamental mechanisms of cell adhesion. Experiments have found that cell detachment shows strong rate dependence, which is mostly attributed to the binding-unbinding kinetics of receptor-ligand bond. However, our recent study showed that the cellular volume regulation can significantly regulate the dynamics of adherent cell and cell detachment. How this cellular volume regulation contributes to the rate dependence of cell detachment remains elusive. Here, we systematically study the role of cellular volume regulation in the rate dependence of cell detachment by investigating the cell detachments of nonspecific adhesion and specific adhesion. We find that the cellular volume regulation and the bond kinetics dominate the rate dependence of cell detachment at different time scales. We further test the validity of the traditional Johnson-Kendall-Roberts (JKR) contact model and the detachment model developed by Wyart and Gennes et al (W-G model). When the cell volume is changeable, the JKR model is not appropriate for both the detachments of convex cells and concave cells. The W-G model is valid for the detachment of convex cells but is no longer applicable for the detachment of concave cells. Finally, we show that the rupture force of adherent cells is also highly sensitive to substrate stiffness, since an increase in substrate stiffness will lead to more associated bonds. These findings can provide insight into the critical role of cell volume in cell detachment and might have profound implications for other adhesion-related physiological processes.

Electric field effects on the dynamics of bubble detachment from an inclined surface

International Nuclear Information System (INIS)

Di Marco, P; Morganti, N; Saccone, G

2015-01-01

An experimental apparatus to study bubble detachment from an inclined surface under the action of electric forces is described. It consists of a container filled with FC72 at room temperature and pressure where a train of gas bubbles is injected from an orifice. An electrostatic field can be imposed around the bubble, while the cell can be tilted from 0 to 90°. It is possible to study interface growth with the aid of high-speed cinematography. Since the interface is asymmetrical, a mirror system allowed to acquire, in the same frame, two images at 90° of the bubble. Different inclinations, injection rates and voltages were tested in order to couple the effects of shear gravity and electric field. Curvature and contact angles have been derived with appropriate interpolation methods of the profile. Force balances on the bubble were checked, finding an electric force, which, at first pulls the bubbles from the orifice, then pushes it against the surface. The motion of the center of gravity confirms this behaviour. A power balance has been developed to determine the energy contributions, revealing that surface growth incorporates both the effects of inlet power and electric field. (paper)

Jet Inlet Efficiency

Science.gov (United States)

2013-08-08

AFRL-RW-EG-TR-2014-044 Jet Inlet Efficiency Nigel Plumb Taylor Sykes-Green Keith Williams John Wohleber Munitions Aerodynamics Sciences...CONTRACT NUMBER N/A 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) Nigel Plumb Taylor Sykes-Green Keith Williams John

From detached to attached buildup complexes

DEFF Research Database (Denmark)

Rafaelsen, B.; Elvebakk, G.; Andreassen, K.

2008-01-01

-like ridges and possibly areas with restricted circulation. Warm-water carbonate buildups, forming ridges and isolated mounds, occur in the Gipsdalen Group (latest Serpukhovian-mid-Sakmarian), where they initially grew in a detached platform setting. The carbonate buildups are several tens of kilometres long...... deposition and buildup growth bridged the detached platform with the attached platform. In the Bjarmeland Group (Lower Permian) 0.35-4.8 km wide, 1.5-27 km long and 60-420 m thick cool-water bryozoan-dominated straight, sinuous and continuous carbonate ridges or atoll-like ridges are located on top...

Round atrophic holes in lattice degeneration--an important cause of phakic retinal detachment.

Science.gov (United States)

Tillery, W V; Lucier, A C

1976-01-01

Round atrophic holes in lattice degeneration are an important cause of phakic retinal detachment. Detachments due solely to round holes in lattice accounted for almost 2.8% of all retinal detachments treated at Wills Eye Hospital from January 1970 to August 1973. These detachments had the following important characteristics: 1. One of the patients were under the age of 30 years. 2. Over 75% of the patients had refractive errors more myopic than -3 D spherical equivalent. 3. Inferior detachments were slightly more common than superior detachments. When located inferiorly, there was a tendency for slow progression as indicated by the frequent presence of pigmented demarcation lines. 4. Surgical repair with standard scleral buckling techniques was successful in 98% of these detachments. Young, moderate to highly myopic patients with round holes in areas of lattice degeneration seem to have a greater risk of developing this type of detachment. Patients with the triad of youth, myopia, and round holes in lattice degeneration deserve close observation.

Lattice degeneration of the retina and retinal detachment.

Science.gov (United States)

Semes, L P

1992-01-01

Lattice retinal degeneration is considered the most significant peripheral retinal disorder potentially predisposing to retinal breaks and retinal detachment. Lattice degeneration affects the vitreous and inner retinal layers with secondary changes as deep as the retinal pigment epithelium and perhaps the choriocapillaris. Variations in clinical appearance are the rule; geographically, lattice lesions favor the vertical meridians between the equator and the ora serrata. Lattice degeneration begins early in life and has been reported in sequential generations of the same family. Along with its customary bilateral occurrence, lattice shares other characteristics of a dystrophy. The association between the vitreous and retina in lattice lesions may be responsible for the majority of lattice-induced retinal detachments. The tumultuous event of posterior vitreous separation in the presence of abnormally strong vitreoretinal adherence is the trigger for a retinal tear that, in turn, may lead to retinal detachment. Although retinal holes in young patients with lattice degeneration may play a role in the evolution of retinal detachment, the clinical course of lattice degeneration seems to be one of dormancy rather than of progressive change. This discussion outlines the pathophysiology of lattice retinal degeneration and the relationship of pathophysiology to clinical presentation. The epidemiology of lattice degeneration is summarized, as are the possible precursors to retinal detachment. A clinical characterization of the natural history of lattice degeneration is offered, and interventions for complications are described. To conclude, management strategies from a primary-care standpoint are reviewed.

36 CFR 13.320 - Preference to Cook Inlet Region, Incorporated.

Science.gov (United States)

2010-07-01

... Region, Incorporated. 13.320 Section 13.320 Parks, Forests, and Public Property NATIONAL PARK SERVICE... to Cook Inlet Region, Incorporated. (a) The Cook Inlet Region, Incorporated (CIRI), in cooperation with village corporations within the Cook Inlet region when appropriate, will have a right of first...

Detection of detachments and inhomogeneities in frescos by Compton scattering

International Nuclear Information System (INIS)

Castellano, A.; Cesareo, R.; Buccolieri, G.; Donativi, M.; Palama, F.; Quarta, S.; De Nunzio, G.; Brunetti, A.; Marabelli, M.; Santamaria, U.

2005-01-01

A mobile instrument has been developed for the detection and mapping of detachments in frescos by using Compton back scattered photons. The instrument is mainly composed of a high energy X-ray tube, an X-ray detection system and a translation table. The instrument was first applied to samples simulating various detachment situations, and then transferred to the Vatican Museum to detect detachments and inhomogeneities in the stanza di Eliodoro, one of the 'Raphael's stanze'

A Meta-Analysis on Antecedents and Outcomes of Detachment from Work

Science.gov (United States)

Wendsche, Johannes; Lohmann-Haislah, Andrea

2017-01-01

Detachment from work has been proposed as an important non-work experience helping employees to recover from work demands. This meta-analysis (86 publications, k = 91 independent study samples, N = 38,124 employees) examined core antecedents and outcomes of detachment in employee samples. With regard to outcomes, results indicated average positive correlations between detachment and self-reported mental (i.e., less exhaustion, higher life satisfaction, more well-being, better sleep) and physical (i.e., lower physical discomfort) health, state well-being (i.e., less fatigue, higher positive affect, more intensive state of recovery), and task performance (small to medium sized effects). However, average relationships between detachment and physiological stress indicators and work motivation were not significant while associations with contextual performance and creativity were significant, but negative. Concerning work characteristics, as expected, job demands were negatively related and job resources were positively related to detachment (small sized effects). Further, analyses revealed that person characteristics such as negative affectivity/neuroticism (small sized effect) and heavy work investment (medium sized effect) were negatively related to detachment whereas detachment and demographic variables (i.e., age and gender) were not related. Moreover, we found a medium sized average negative relationship between engagement in work-related activities during non-work time and detachment. For most of the examined relationships heterogeneity of effect sizes was moderate to high. We identified study design, samples' gender distribution, and affective valence of work-related thoughts as moderators for some of these aforementioned relationships. The results of this meta-analysis point to detachment as a non-work (recovery) experience that is influenced by work-related and personal characteristics which in turn is relevant for a range of employee outcomes. PMID:28133454

Simultaneous mass detection for direct inlet mass spectrometry

International Nuclear Information System (INIS)

Gordon, R.L.

1979-05-01

The evolution of analytical techniques for application in trace analysis has led to interest in practical methods for real-time monitoring. Direct inlet mass spectrometry (DIMS) has been the subject of considerable activity in recent years. A DIMS instrument is described which consists of an inlet system designed to permit particles entrained in the inlet air stream to strike a hot, oxidized rhenium filament which serves as a surface ionization source. A mass analyzer and detection system then permits identification of the elemental composition of particulates which strike the filament

Current surgery of retinal detachment recurrence. Review

Directory of Open Access Journals (Sweden)

V. D. Zakharov

2012-01-01

Full Text Available this review presents a detailed analysis and an experience of surgical treatment of retinal detachment recurrence associated with light silicone oil tamponade of vitreous cavity. Approaches and variants of treatment were described in the historical aspect and till now. there are considered general and particular issues in case of retinal detachment recurrence appearance, expediency and volume of intraoperative manipulations, time of operation and choice of temporary substitute of vitreous body for a purpose of postoperative tamponade of vitreous cavity.

Detection of detachments and inhomogeneities in frescos by Compton scattering

Energy Technology Data Exchange (ETDEWEB)

Castellano, A. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Cesareo, R. [Istituto di Matematica e Fisica, Universita di Sassari, 07100 Sassari (Italy) and INFN, Sezione di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari (Italy)]. E-mail: cesareo@uniss.it; Buccolieri, G. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Donativi, M. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); Palama, F. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Quarta, S. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); De Nunzio, G. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Brunetti, A. [Istituto di Matematica e Fisica, Universita di Sassari, 07100 Sassari (Italy); INFN, Sezione di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari (Italy); Marabelli, M. [Istituto Centrale del Restauro, P.zza S. Francesco di Paola, 00184 Rome (Italy); Santamaria, U. [Laboratori dei Musei Vaticani, Citta del Vaticano, Rome (Italy)

2005-07-01

A mobile instrument has been developed for the detection and mapping of detachments in frescos by using Compton back scattered photons. The instrument is mainly composed of a high energy X-ray tube, an X-ray detection system and a translation table. The instrument was first applied to samples simulating various detachment situations, and then transferred to the Vatican Museum to detect detachments and inhomogeneities in the stanza di Eliodoro, one of the 'Raphael's stanze'.

Disappearance of a detached vapor mass in subcooled water

International Nuclear Information System (INIS)

Inada, Shigeaki; Miyasaka, Yoshiki; Izumi, Ryotaro.

1986-01-01

Experiments on pool transition boiling of water under atmospheric pressure on a heated surface 10 mm in diameter were conducted for subcooling 15 - 50 K. The mass flux of condensation of a detached coalescent vapor bubble was experimentally estimated by a mathematical model based on the mass transfer mechanism of condensation. As a result, it is clarified that the mass flux of condensation of the detached bubble was influenced by the initial growing velocity of a vapor bubble immediately following the detached bubble. The disappearance velocity of the detached bubble defined as a ratio of the bubble diameter at the departure to the time required until the disappearance, is in the range 0.2 to 2.0 m/sec. The disappearance velocity is proportional to the initial growing velocity of the bubble, to the square of the heat flux of the heated surface and to the cube of the wall superheat, separately. (author)

A chick model of retinal detachment: cone rich and novel.

Directory of Open Access Journals (Sweden)

Colleen M Cebulla

Full Text Available Development of retinal detachment models in small animals can be difficult and expensive. Here we create and characterize a novel, cone-rich retinal detachment (RD model in the chick.Retinal detachments were created in chicks between postnatal days 7 and 21 by subretinal injections of either saline (SA or hyaluronic acid (HA. Injections were performed through a dilated pupil with observation via surgical microscope, using the fellow eye as a control. Immunohistochemical analyses were performed at days 1, 3, 7, 10 and 14 after retinal detachment to evaluate the cellular responses of photoreceptors, Müller glia, microglia and nonastrocytic inner retinal glia (NIRG. Cell proliferation was detected with bromodeoxyuridine (BrdU-incorporation and by the expression of proliferating cell nuclear antigen (PCNA. Cell death was detected with terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL. As in mammalian models of RD, there is shortening of photoreceptor outer segments and mis-trafficking of photoreceptor opsins in areas of RD. Photoreceptor cell death was maximal 1 day after RD, but continued until 14 days after RD. Müller glia up-regulated glial fibriliary acidic protein (GFAP, proliferated, showed interkinetic nuclear migration, and migrated to the subretinal space in areas of detachment. Microglia became reactive; they up-regulated CD45, acquired amoeboid morphology, and migrated toward outer retina in areas of RD. Reactive NIRG cells accumulated in detached areas.Subretinal injections of SA or HA in the chick eye successfully produced retinal detachments and cellular responses similar to those seen in standard mammalian models. Given the relatively large eye size, and considering the low cost, the chick model of RD offers advantages for high-throughput studies.

Happy, healthy, and productive: the role of detachment from work during nonwork time.

Science.gov (United States)

Fritz, Charlotte; Yankelevich, Maya; Zarubin, Anna; Barger, Patricia

2010-09-01

Mentally distancing oneself from work during nonwork time can help restore resources lost because of work demands. In this study, we examined possible outcomes of such psychological detachment from work, specifically well-being and job performance. Although employees may need to mentally detach from work to restore their well-being, high levels of detachment may require a longer time to get back into "working mode," which may be negatively associated with job performance. Our results indicate that higher levels of self-reported detachment were associated with higher levels of significant other-reported life satisfaction as well as lower levels of emotional exhaustion. In addition, we found curvilinear relationships between psychological detachment and coworker reported job performance (task performance and proactive behavior). Thus, although high psychological detachment may enhance employee well-being, it seems that medium levels of detachment are most beneficial for job performance. Copyright 2010 APA, all rights reserved

Mechanisms of redox metabolism and cancer cell survival during extracellular matrix detachment.

Science.gov (United States)

Hawk, Mark A; Schafer, Zachary T

2018-01-16

Non-transformed cells that become detached from the extracellular matrix (ECM) undergo dysregulation of redox homeostasis and cell death. In contrast, cancer cells often acquire the ability to mitigate programmed cell death pathways and recalibrate the redox balance to survive after ECM detachment, facilitating metastatic dissemination. Accordingly, recent studies of the mechanisms by which cancer cells overcome ECM detachment-induced metabolic alterations have focused on mechanisms in redox homeostasis. The insights into these mechanisms may inform the development of therapeutics that manipulate redox homeostasis to eliminate ECM-detached cancer cells. Here, we review how ECM-detached cancer cells balance redox metabolism for survival. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

Numerical Simulation of Boundary Layer Ingesting (BLI) Inlet-Fan Interaction

Science.gov (United States)

Giuliani, James; Chen, Jen-Ping; Beach, Timothy; Bakhle, Milind

2014-01-01

Future civil transport designs may incorporate engine inlets integrated into the body of the aircraft to take advantage of efficiency increases due to weight and drag reduction. Additional increases in engine efficiency are predicted if the inlet ingests the lower momentum boundary layer flow. Previous studies have shown, however, that efficiency benefits of Boundary Layer Ingesting (BLI) ingestion are very sensitive to the magnitude of fan and duct losses, and blade structural response to the non-uniform flow field that results from a BLI inlet has not been studied in-depth. This paper presents an effort to extend the modeling capabilities of an existing rotating turbomachinery unsteady analysis code to include the ability to solve the external and internal flow fields of a BLI inlet. The TURBO code has been a successful tool in evaluating fan response to flow distortions for traditional engine/inlet integrations, such as the development of rotating stall and inlet distortion through compressor stages. This paper describes the first phase of an effort to extend the TURBO model to calculate the external and inlet flowfield upstream of fan so that accurate pressure distortions that result from BLI configurations can be computed and used to analyze fan aerodynamics and structural response. To validate the TURBO program modifications for the BLI flowfield, experimental test data obtained by NASA for a flushmounted S-duct with large amounts of boundary layer ingestion was modeled. Results for the flow upstream and in the inlet are presented and compared to experimental data for several high Reynolds number flows to validate the modifications to the solver. Quantitative data is presented that indicates good predictive capability of the model in the upstream flow. A representative fan is attached to the inlet and results are presented for the coupled inlet/fan model. The impact on the total pressure distortion at the AIP after the fan is attached is examined.

Nonresonant excess photon detachment of negative hydrogen ions

International Nuclear Information System (INIS)

Gulley, M. S.; Zhao, Xin Miao; Bryant, H. C.; Strauss, Charlie E. M.; Funk, David J.; Stintz, A.; Rislove, D. C.; Kyrala, G. A.; Ingalls, W. B.; Miller, W. A.

1999-01-01

One-photon detachment and two-photon nonresonant excess photon detachment of electrons from the H - ion (outer-electron binding energy = 0.7542 eV) are observed with 1.165 eV laser pulses from a Nd:YAG laser (where YAG denotes yttrium aluminum garnet). A Penning ion source produces a pulsed 8 μA, 35 keV H - beam that intersects a laser beam cylindrically focused down to a 17 μm full width at half maximum waist in the ion beam direction, creating a high-intensity interaction region with peak intensities of up to 10 11 W/cm 2 . The interaction time is 7 ps. The detached electrons are detected by a time-of-flight apparatus enabling us to detect a very small two-photon signal in the presence of a very large signal from single photon detachments. By rotating the linear polarization angle, we study the angular distribution of the electrons for both one- and two-photon detachments. The spectra are modeled to determine the asymmetry parameters and one- and two-photon cross sections. We find β 2 to be 2.54+0.44/-0.60 and β 4 to be 2.29+0.07/-0.31, corresponding to a D state of 89+3/-12% of the S wave and D wave detachments for the two-photon results. The relative phase angle between the S and D amplitudes is measured to be less than 59 degree sign . The measured cross sections are found to be consistent with theoretical predictions. The one-photon photodetachment cross section is measured to be (3.6±1.7)x10 -17 cm 2 . The two-photon photodetachment generalized cross section is (1.3±0.5)x10 -48 cm 4 sec, consistent with theoretical calculations of the cross section. The three-photon generalized cross section is less than 4.4x10 -79 cm 6 sec 2 . (c) 1999 The American Physical Society

Ohmic discharges in Tore Supra - Marfes and detached plasmas

International Nuclear Information System (INIS)

Vallet, J.C.

1990-01-01

The Tore Supra plasma characteristics are given. The observed discharges are either leaning on the graphite inner first wall or limited by movable pump limiters located outboard and at the bottom of the vacuum chamber. The particular plasma conditions which lead to marfes and detached plasmas in ohmically heated He and D2 discharges limited by the inner wall are investigated. The results show that the ratio of radiated power to ohmic power increase linearly with M.g. As M.g rises, attached plasma, marfe and detached plasma are sequentially observed. Detached plasma with an effective radius as small as. 7 times the limiter radius was observed on Tore Supra

Shape Evolution of Detached Bridgman Crystals Grown in Microgravity

Science.gov (United States)

Volz, M. P.; Mazuruk, K.

2015-01-01

A theory describing the shape evolution of detached Bridgman crystals in microgravity has been developed. A starting crystal of initial radius r0 will evolve to one of the following states: Stable detached gap; Attachment to the crucible wall; Meniscus collapse. Only crystals where alpha plus omega is great than 180 degrees will achieve stable detached growth in microgravity. Results of the crystal shape evolution theory are consistent with predictions of the dynamic stability of crystallization (Tatarchenko, Shaped Crystal Growth, Kluwer, 1993). Tests of transient crystal evolution are planned for ICESAGE, a series of Ge and GeSi crystal growth experiments planned to be conducted on the International Space Station (ISS).

FACTORS ASSOCIATED WITH VISUAL OUTCOME AFTER MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT SURGERY.

Science.gov (United States)

Park, Dae Hyun; Choi, Kyung Seek; Sun, Hae Jung; Lee, Sung Jin

2018-01-01

To evaluate preoperative factors influencing the visual outcome and postoperative factors associated with the changes in visual acuity, after reattachment surgery to treat macula-off rhegmatogenous retinal detachment. A total of 180 eyes of 180 patients who underwent reattachment surgery to treat macula-off rhegmatogenous retinal detachment, and who were followed up for more than 12 months, were reviewed retrospectively. Preoperative and postoperative characteristics, including optical coherence tomography findings, were comprehensively analyzed using univariate and multivariate models to evaluate preoperative factors influencing best-corrected visual acuity 12 months after macula-off rhegmatogenous retinal detachment surgery and postoperative factors associated with changes in best-corrected visual acuity after surgery. Preoperatively, the extent of detachment (P = 0.037), macula-off duration (P macula-off rhegmatogenous retinal detachment surgery were the extent of detachment, macula-off duration, and external limiting membrane integrity. Postoperatively, predictive factors were the outer retinal microstructures, particularly the photoreceptor outer segment layer.

[Clinical Characteristics of Rhegmatogenous Retinal Detachment in Highly Myopic and Phakic Eyes].

Science.gov (United States)

Orihara, Tadashi; Hirota, Kazunari; Yokota, Reiji; Kunita, Daisuke; Itoh, Yuji; Rii, Tosho; Koto, Takashi; Hiraoka, Tomoyuki; Inoue, Makoto; Hirakata, Akito

2016-05-01

To evaluate clinical characteristics of rhegmatogenous retinal detachment in high myopic and phakic eyes. The subjects were 1174 eyes of phakic rhegmatogenous retinal detachment detected in 1199 eyes that underwent initial vitreoretinal surgery between April 2006 and March 2011. Eyes with macular hole retinal detachment or secondary retinal detachment were excluded. The 486 eyes with high myopia (spherical equivalent ≤ -6.0 D or axial length ≥ 26.5 mm) and the 688 eyes with non-high myopia were compared. The mean age was significantly younger in the high myopia group (42.7 ± 14.2 years old, p lattice degeneration were more frequent (16.7%, 20.4%, respectively). The incidences of the retinal detachment in younger age and those caused by retinal holes were higher in the high myopia group. Higher incidence of retinal detachment and lattice degeneration in the fellow eyes of the high myopia group indicated that careful observation also in the fellow eyes was recommended.

Classification of posterior vitreous detachment

Science.gov (United States)

Kakehashi, Akihiro; Takezawa, Mikiko; Akiba, Jun

2014-01-01

Diagnosing a posterior vitreous detachment (PVD) is important for predicting the prognosis and determining the indication for vitreoretinal surgery in many vitreoretinal diseases. This article presents both classifications of a PVD by slit-lamp biomicroscopy and of a shallow PVD by optical coherence tomography (OCT). By biomicroscopy, the vitreous condition is determined based on the presence or absence of a PVD. The PVD then is classified as either a complete posterior vitreous detachment (C-PVD) or a partial posterior vitreous detachment (P-PVD). A C-PVD is further divided into a C-PVD with collapse and a C-PVD without collapse, while a P-PVD is divided into a P-PVD with shrinkage of the posterior hyaloid membrane (P-PVD with shrinkage) and a P-PVD without shrinkage of the posterior hyaloid membrane (P-PVD without shrinkage). A P-PVD without shrinkage has a subtype characterized by vitreous gel attachment through the premacular hole in a posterior hyaloid membrane to the macula (P-PVD without shrinkage [M]). By OCT, a shallow PVD is classified as the absence of a shallow PVD or as a shallow PVD. A shallow PVD is then subclassified as a shallow PVD without shrinkage of the posterior vitreous cortex, a shallow PVD with shrinkage of the posterior vitreous cortex, and a peripheral shallow PVD. A shallow PVD without shrinkage of the posterior vitreous cortex has two subtypes: an age-related shallow PVD and a perifoveal PVD associated with a macular hole. PMID:24376338

Detached Statements

Directory of Open Access Journals (Sweden)

Mark McBride

2018-04-01

Full Text Available Joseph Raz has introduced an interesting class of statements —detached statements— into the philosophical lexicon. In brief, such statements are (informa- tive normative statements, yet the speaker does not, in so uttering them, express or convey acceptance of the point of view of the hearer to whom they are addressed (as contrasted with committed statements, where the speaker does express or convey such acceptance. I propose to offer a novel analysis of such statements (and to clear away some confusions about them. In brief, such statements will be analysed as wide-scope normative conditionals.

Kinematic Fitting of Detached Vertices

Energy Technology Data Exchange (ETDEWEB)

Mattione, Paul [Rice Univ., Houston, TX (United States)

2007-05-01

The eg3 experiment at the Jefferson Lab CLAS detector aims to determine the existence of the $\\Xi_{5}$ pentaquarks and investigate the excited $\\Xi$ states. Specifically, the exotic $\\Xi_{5}^{--}$ pentaquark will be sought by first reconstructing the $\\Xi^{-}$ particle through its weak decays, $\\Xi^{-}\\to\\pi^{-}\\Lambda$ and $\\Lambda\\to\\pi^{-}$. A kinematic fitting routine was developed to reconstruct the detached vertices of these decays, where confidence level cuts on the fits are used to remove background events. Prior to fitting these decays, the exclusive reaction $\\gamma D\\rightarrow pp\\pi^{-}$ was studied in order to correct the track measurements and covariance matrices of the charged particles. The $\\Lambda\\rightarrow p\\pi^{-}$ and $\\Xi^{-}\\to\\pi^{-}\\Lambda$ decays were then investigated to demonstrate that the kinematic fitting routine reconstructs the decaying particles and their detached vertices correctly.

Classification of tidal inlets along the Central east coast of India

Digital Repository Service at National Institute of Oceanography (India)

Reddy, N.A.; Vikas, M.; Rao, S.; JayaKumar S.

) as long as the alongshore sediment bypasses the tidal inlet. Classification of coastal systems in a broader view is necessary for the management of tidal inlets. There are several methods to classify tidal inlets based on different perspectives namely geo...

U-Pb zircon age for a volcanic suite in the Rankin Inlet Group, Rankin Inlet map area, District of Keewatin, Northwest Territories

International Nuclear Information System (INIS)

Tella, S.; Roddick, J.C.; VanBreemen, O.

1996-01-01

U-Pb zircon analyses from a felsic band within dominantly mafic volcanics of the Rankin Inlet Group yields a U-Pb upper concordia intercept age of 2663 ± 3 Ma. These supracrustals at Rankin Inlet appear to be 15-20 Ma younger than volcanics of the Kaminak Group in the Tavani area, 70 km to the southwest. The 2.68-2.66 Ga volcanism in the Tavani and Rankin Inlet areas coincided with the last stage of the main phase of magmatism in the Slave Structural Province. (author). 16 refs., 1 tab., 3 figs

U-Pb zircon age for a volcanic suite in the Rankin Inlet Group, Rankin Inlet map area, District of Keewatin, Northwest Territories

Energy Technology Data Exchange (ETDEWEB)

Tella, S; Roddick, J C; VanBreemen, O [Geological Survey of Canada, Ottawa, ON (Canada)

1997-12-31

U-Pb zircon analyses from a felsic band within dominantly mafic volcanics of the Rankin Inlet Group yields a U-Pb upper concordia intercept age of 2663 {+-} 3 Ma. These supracrustals at Rankin Inlet appear to be 15-20 Ma younger than volcanics of the Kaminak Group in the Tavani area, 70 km to the southwest. The 2.68-2.66 Ga volcanism in the Tavani and Rankin Inlet areas coincided with the last stage of the main phase of magmatism in the Slave Structural Province. (author). 16 refs., 1 tab., 3 figs.

Rhegmatogenous retinal detachment and conventional surgical treatment.

Science.gov (United States)

Golubovic, M

2013-01-01

The aim of the paper was to present the efficacy and indications for application of conventional surgical treatment of retinal detachment by using external implants, that is,application of encircling band and buckle. This study comprised patients from the University Eye Clinic in Skopje. A total of 33 patients were diagnosed and surgically treated in the period between May 2010 and August 2011. Conventional surgery was applied in smaller number of patients whose changes of the vitreous body were manifested by detachment of posterior hyaloid membrane, syneresis, with appearance of a small number of pigment cells in the vitreous body and synchysis, and the very retina was with fresh detachment without folds or epiretinal changes (that is, PVR A grade). There were a larger number of patients with more distinct proliferative changes of the vitreous body and of the retina, grades PVR B to C1-C2, and who also underwent the same surgical approach. Routine ophthalmologic examinations were performed, including: determination of visual acuity by Snellen's optotypes, determination of eye pressure with Schiotz's tonometer, examination of anterior segment on biomicroscopy, indirect biomicroscopy of posterior eye segment (vitreous body and retina) and examination on biomicroscopy with Goldmann prism, B scan echography of the eyes before and after surgical treatment. Conventional treatment was used by external application of buckle or application of buckle and encircling band. In case of one break, radial buckle was applied and in case of multiple breaks in one quadrant limbus parallel buckle was applied. Besides buckle, encircling band was applied in patients with total or subtotal retinal detachment with already present distinct changes in the vitreous body (PVR B or C1-C2) and degenerative changes in the vitreous body. Breaks were closed with cryopexy. The results obtained have shown that male gender was predominant and that the disease was manifested in younger male adults

On The Detachment of Massive Trans-Neptunian Objects

Science.gov (United States)

Fleisig, Jacob; Madigan, Ann-Marie; Zderic, Alexander

2018-06-01

Our Solar System contains a large population of icy bodies stretching well beyond the orbit of Neptune. These objects, known collectively as the Scattered Disk, are remnants from the early formation of the Solar System that were scattered outward from their birth location by Neptune. But not all fit the bill.Sedna, one particularly massive Trans-Neptunian Object (TNO), does not conform to the scattering pattern. Its orbital eccentricity (e) is much lower than expected for a scattered object. This means its perihelion distance (proportional to 1-e) is much larger than the orbit of Neptune, or that it is “detached” from the main Solar System. Many more TNOs share similarities with Sedna. These observations suggest that there is a large population of detached TNOs that have a dynamical history different than that of the objects scattered by Neptune.The physical mechanism by which these massive minor planets become detached is currently unknown. However, we have discovered a phenomenon, driven by differential precession between TNOs of different masses and mutual secular gravitational torques, that naturally detach massive minor planets. This mechanism could have notable consequences for the outer Solar System and may shed some light on the origin of the detached population of minor planets near the Scattered Disk.

Enzymatic detachment of therapeutic mesenchymal stromal cells grown on glass carriers in a bioreactor.

Science.gov (United States)

Salzig, Denise; Schmiermund, Alexandra; P Grace, Pablo; Elseberg, Christiane; Weber, Christian; Czermak, Peter

2013-01-01

Cell therapies require the in vitro expansion of adherent cells such as mesenchymal stromal cells (hMSCs) in bioreactor systems or other culture environments, followed by cell harvest. As hMSCs are strictly adherent cells, cell harvest requires cell detachment. The use of hMSCs for cell therapy requires GMP production in accordance with the guidelines for advanced therapeutic medical products. Therefore, several GMP-conform available proteolytic enzymes were investigated for their ability to promote hMSC detachment. An allogeneic hMSC cell line (hMSC-TERT) that is used in clinical trials in the form of alginate cell capsules was chosen as a model. This study investigated the influence of several factors on the outcome of proteolytic hMSC-TERT detachment. Therefore, hMSC-TERT detachment was analyzed in different cultivation systems (static, dynamic) and in combination with further cell processing including encapsulation. Only two of the commercially available enzymes (AccutaseTM, TrypZeanTM) that fulfill all process requirements (commercial availability, cost, GMP conditions during manufacturing and non-animal origin) are found to be generally suitable for detaching hMSC-TERT. Combining cell detachment with encapsulation demonstrated a high impact of the experimental set up on cell damage. It was preferable to reduce the temperature during detachment and limit the detachment time to a maximum of 20 minutes. Cell detachment in static systems was not comparable with detachment in dynamic systems. Detachment yields in dynamic systems were lower and cell damage was higher for the same experimental conditions. Finally, only TrypZeanTM seemed to be suitable for the detachment of hMSC-TERT from dynamic reactor systems.

Experimental Research on Optimizing Inlet Airflow of Wet Cooling Towers under Crosswind Conditions

Science.gov (United States)

Chen, You Liang; Shi, Yong Feng; Hao, Jian Gang; Chang, Hao; Sun, Feng Zhong

2018-01-01

A new approach of installing air deflectors around tower inlet circumferentially was proposed to optimize the inlet airflow and reduce the adverse effect of crosswinds on the thermal performance of natural draft wet cooling towers (NDWCT). And inlet airflow uniformity coefficient was defined to analyze the uniformity of circumferential inlet airflow quantitatively. Then the effect of air deflectors on the NDWCT performance was investigated experimentally. By contrast between inlet air flow rate and cooling efficiency, it has been found that crosswinds not only decrease the inlet air flow rate, but also reduce the uniformity of inlet airflow, which reduce NDWCT performance jointly. After installing air deflectors, the inlet air flow rate and uniformity coefficient increase, the uniformity of heat and mass transfer increases correspondingly, which improve the cooling performance. In addition, analysis on Lewis factor demonstrates that the inlet airflow optimization has more enhancement of heat transfer than mass transfer, but leads to more water evaporation loss.

Inhibition of microparticle release triggers endothelial cell apoptosis and detachment

NARCIS (Netherlands)

Abid Hussein, Mohammed N.; Böing, Anita N.; Sturk, Augueste; Hau, Chi M.; Nieuwland, Rienk

2007-01-01

Endothelial cell cultures contain caspase 3-containing microparticles (EMP), which are reported to form during or after cell detachment. We hypothesize that also adherent endothelial cells release EMP, thus protecting these cells from caspase 3 accumulation, detachment and apoptosis. Human umbilical

Tracing detached and attached care practices in nursing education

DEFF Research Database (Denmark)

Soffer, Ann Katrine B.

2014-01-01

The implementation of skills labs in Danish nursing education can, in itself, be viewed as a complexity. The students are expected to eventually carry out their work in a situated hospital practice, but they learn their professional skills in a different space altogether, detached and removed from...... of care are not explicated in the curriculum or textbooks; however, they surfaced once this crooked approach to studying care in a simulated practice was applied. The article starts from the assertion that detached engagements are not recognized within the field of nursing education as an equal component...... analytical approach to care work, as involving both attached and detached engagement within Danish nursing education, is advocated....

Effect of inlet straighteners on centrifugal fan performance

Energy Technology Data Exchange (ETDEWEB)

Bayomi, N.N.; Abdel Hafiz, A. [Faculty of Engineering, Mataria, Helwan University, 11718 Masaken, El-Helmia, Cairo (Egypt); Osman, A.M. [Faculty of Engineering, Shoubra, Zagazig University, Cairo (Egypt)

2006-11-15

The use of straighteners in the inlet duct of centrifugal fans is suggested for eliminating any inlet distortion. An experimental investigation was performed to study the effect of inlet straighteners on the performance characteristics of centrifugal fans. Two types of straighteners were used, circular tubes and zigzag cross section, with different lengths. Circular tubes with different diameters have been investigated. The study was conducted on three types of fans, namely radial, backward with exit blade angles 60{sup o} and 75{sup o} and forward with 105{sup o} and 120{sup o}. The results confirm that the inlet straighteners exhibit different effects on the fan performance for the different blade angles. Accordingly, the results indicate the selection of long circular tube straighteners with large diameter for radial blades, long zigzag type for backward 60{sup o} blade angle and short zigzag type for backward 75{sup o} blade angle. Generally, good improvements in efficiency are observed for radial and backward blades on account of a slight drop in static head. In addition, an increase in the flow margin up to 12% and a decrease in the noise level from 3 to 5dB are indicated compared to the free inlet condition. On the contrary, unfavorable influences are exerted on the forward fan performance. (author)

Retinal Detachment due to CrossFit Training Injury.

Science.gov (United States)

Joondeph, Stephanie A; Joondeph, Brian C

2013-01-01

The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

Retinal Detachment due to CrossFit Training Injury

OpenAIRE

Joondeph, Stephanie A.; Joondeph, Brian C.

2013-01-01

The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

CFD application to supersonic/hypersonic inlet airframe integration. [computational fluid dynamics (CFD)

Science.gov (United States)

Benson, Thomas J.

1988-01-01

Supersonic external compression inlets are introduced, and the computational fluid dynamics (CFD) codes and tests needed to study flow associated with these inlets are outlined. Normal shock wave turbulent boundary layer interaction is discussed. Boundary layer control is considered. Glancing sidewall shock interaction is treated. The CFD validation of hypersonic inlet configurations is explained. Scramjet inlet modules are shown.

Seismic Slip on an Oblique Detachment Fault at Low Angles

Science.gov (United States)

Janecke, S. U.; Steely, A. N.; Evans, J. P.

2008-12-01

Pseudotachylytes are one of the few accepted indicators of seismic slip along ancient faults. Low-angle normal faults have produced few large earthquakes in historic times and low-angle normal faults (detachment faults) are typically severely misoriented relative to a vertical maximum compressive stress. As a result many geoscientists question whether low-angle normal faults produce earthquakes at low angles. Relationships in southern California show that a major low-angle normal-oblique fault slipped at low angles and produced large earthquakes. The exhumed Late Cenozoic West Salton detachment fault preserves spectacular fault- related pseudotachylytes along its fault plane and injected into its hanging wall and footwall. Composite pseudotachylyte zones are up to 1.25 m thick and persists over lateral distances of at least 10's of meters. Pseudotachylyte is common in most thin sections of damaged fault rocks with more than 20% (by volume) of cataclasite. We recognized the presence of original melt using numerous criteria: abundant spherulites in thin sections, injection structures at both the thin-section and outcrop scale, black aphanitic textures, quenched vein margins, variations in microcrystallite textures and/or size with respect to the vein margin, and glassy textures in hand sample. Multiple earthquakes are inferred to produce the layered "stratigraphy" in some exposures of pseudotachylytes. We infer that the West Salton detachment fault formed and slipped at low angles because it nearly perfectly reactivates a Cretaceous ductile thrust system at the half km scale and dips between 10 and 45 degrees. The about 30 degree NNE dip of the detachment fault on the north side of Yaqui Ridge is likely steeper than its dip during detachment slip because there is local steepening on the flanks of the Yaqui Ridge antiform in a contractional stepover of a crosscutting Quaternary San Felipe dextral fault zone. These relationships indicate a low dip on the detachment

Dynamics of the inlet system of a four-stroke engine

Science.gov (United States)

Boden, R H; Schecter, Harry

1944-01-01

Tests were run on a single-cylinder and a multicylinder four-stroke engine in order to determine the effect of the dynamics of the inlet system upon indicated mean effective pressure. Tests on the single-cylinder engine were made at various speeds, inlet valve timings, and inlet pipe lengths. These tests indicated that the indicated mean effective pressure could be raised considerably at any one speed by the use of a suitably long inlet pipe. Tests at other speeds with this length of pipe showed higher indicated mean effective pressure than with a very short pipe, although not so high as could be obtained with the pipe length adjusted for each speed. A general relation was discovered between optimum time of inlet valve closing and pipe length; namely, that longer pipes require later inlet valve closing in order to be fully effective. Tests were also made on three cylinders connected to a single pipe. With this arrangement, increased volumetric efficiency at low speed was obtainable by using a long pipe, but only with a sacrifice of volumetric efficiency at high speed. Volumetric efficiency at high speed was progressively lower as the pipe length was increased.

The Scale Effects of Engineered Inlets in Urban Hydrologic Processes

Science.gov (United States)

Shevade, L.; Montalto, F. A.

2017-12-01

Runoff from urban surfaces is typically captured by engineered inlets for conveyance to receiving water bodies or treatment plants. Normative hydrologic and hydraulic (H&H) modeling tools generally assume 100% efficient inlets, though observations by the authors suggest this assumption is invalid. The discrepancy is key since the more efficiently the inlet, the more linearly hydrologic processes scale with catchment area. Using several years of remote sensing, the observed efficiencies of urban green infrastructure (GI) facility inlets in New York City are presented, as a function of the morphological and climatological properties of their catchments and events. The rainfall-runoff response is modeled with EPA to assess the degree of inaccuracy that the assumption of efficient inlets introduces in block and neighborhood-scale simulations. Next, an algorithm is presented that incorporates inlet efficiency into SWMM and the improved predictive skill evaluated using Nash-Sutcliffe and root-mean-square error (RMSE). The results are used to evaluate the extent to which decentralized green stormwater management facilities positioned at the low points of urban catchments ought to be designed with larger capacities than their counterparts located further upslope.

The seasonal cycle of Titan's detached haze

Science.gov (United States)

West, Robert A.; Seignovert, Benoît; Rannou, Pascal; Dumont, Philip; Turtle, Elizabeth P.; Perry, Jason; Roy, Mou; Ovanessian, Aida

2018-04-01

Titan's `detached' haze, seen in Voyager images in 1980 and 1981 and monitored by the Cassini Imaging Science Subsystem (ISS) during the period 2004-2017, provides a measure of seasonal activity in Titan's mesosphere with observations over almost half of Saturn's seasonal cycle. Here we report on retrieved haze extinction profiles that reveal a depleted layer (having a diminished aerosol content), visually manifested as a gap between the main haze and a thin, detached upper layer. Our measurements show the disappearance of the feature in 2012 and its reappearance in 2016, as well as details after the reappearance. These observations highlight the dynamical nature of the detached haze. The reappearance seems congruent with earlier descriptions by climate models but more complex than previously described. It occurs in two steps, first as haze reappearing at 450 ± 20 km and one year later at 510 ± 20 km. These observations provide additional tight and valuable constraints about the underlying mechanisms, especially for Titan's mesosphere, that control Titan's haze cycle.

40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.

Science.gov (United States)

2010-07-01

... Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet Intrastate Air Quality Control Region (Alaska) consists of the territorial area encompassed by the boundaries... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Cook Inlet Intrastate Air Quality...

Retinal Detachment due to CrossFit Training Injury

Directory of Open Access Journals (Sweden)

Stephanie A. Joondeph

2013-01-01

Full Text Available The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

The NASA Ames Hypersonic Combustor-Model Inlet CFD Simulations and Experimental Comparisons

Science.gov (United States)

Venkatapathy, E.; Tokarcik-Polsky, S.; Deiwert, G. S.; Edwards, Thomas A. (Technical Monitor)

1995-01-01

Computations have been performed on a three-dimensional inlet associated with the NASA Ames combustor model for the hypersonic propulsion experiment in the 16-inch shock tunnel. The 3-dimensional inlet was designed to have the combustor inlet flow nearly two-dimensional and of sufficient mass flow necessary for combustion. The 16-inch shock tunnel experiment is a short duration test with test time of the order of milliseconds. The flow through the inlet is in chemical non-equilibrium. Two test entries have been completed and limited experimental results for the inlet region of the combustor-model are available. A number of CFD simulations, with various levels of simplifications such as 2-D simulations, 3-D simulations with and without chemical reactions, simulations with and without turbulent conditions, etc., have been performed. These simulations have helped determine the model inlet flow characteristics and the important factors that affect the combustor inlet flow and the sensitivity of the flow field to these simplifications. In the proposed paper, CFD modeling of the hypersonic inlet, results from the simulations and comparison with available experimental results will be presented.

Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet.

Science.gov (United States)

Lutomski, Corinne A; El-Baba, Tarick J; Inutan, Ellen D; Manly, Cory D; Wager-Miller, James; Mackie, Ken; Trimpin, Sarah

2014-07-01

This represents the first report of laserspray ionization vacuum (LSIV) with operation directly from atmospheric pressure for use in mass spectrometry. Two different types of electrospray ionization source inlets were converted to LSIV sources by equipping the entrance of the atmospheric pressure inlet aperture with a customized cone that is sealed with a removable glass plate holding the matrix/analyte sample. A laser aligned in transmission geometry (at 180° relative to the inlet) ablates the matrix/analyte sample deposited on the vacuum side of the glass slide. Laser ablation from vacuum requires lower inlet temperature relative to laser ablation at atmospheric pressure. However, higher inlet temperature is required for high-mass analytes, for example, α-chymotrypsinogen (25.6 kDa). Labile compounds such as gangliosides and cardiolipins are detected in the negative ion mode directly from mouse brain tissue as intact doubly deprotonated ions. Multiple charging enhances the ion mobility spectrometry separation of ions derived from complex tissue samples.

Measuring the force of single protein molecule detachment from surfaces with AFM.

Science.gov (United States)

Tsapikouni, Theodora S; Missirlis, Yannis F

2010-01-01

Atomic force microscopy (AFM) was used to measure the non-specific detachment force of single fibrinogen molecules from glass surfaces. The identification of single unbinding events was based on the characteristics of the parabolic curves, recorded during the stretching of protein molecules. Fibrinogen molecules were covalently bound to Si(3)N(4) AFM tips, previously modified with 3-aminopropyl-dimethyl-ethoxysilane, through a homobifunctional poly(ethylene glycol) linker bearing two hydroxysulfosuccinimide esters. The most probable detachment force was found to be 210 pN, when the tip was retracting with a velocity of 1400 nm/s, while the distribution of the detachment distances indicated that the fibrinogen chain can be elongated beyond the length of the physical conformation before detachment. The dependence of the most probable detachment force on the loading rate was examined and the dynamics of fibrinogen binding to the surface were found amenable to the simple expression of the Bell-Evans theory. The theory's expansion, however, by incorporating the concept of the rupture of parallel residue-surface bonds could only describe the detachment of fibrinogen for a small number of such bonds. Finally, the mathematical expression of the Worm-Like Chain model was used to fit the stretching curves before rupture and two interpretations are suggested for the description of the AFM curves with multiple detachment events.

Boundary conditions for free surface inlet and outlet problems

KAUST Repository

Taroni, M.; Breward, C. J. W.; Howell, P. D.; Oliver, J. M.

2012-01-01

We investigate and compare the boundary conditions that are to be applied to free-surface problems involving inlet and outlets of Newtonian fluid, typically found in coating processes. The flux of fluid is a priori known at an inlet, but unknown

Metabolism during ECM Detachment: Achilles Heel of Cancer Cells?

Science.gov (United States)

Mason, Joshua A; Hagel, Kimberly R; Hawk, Mark A; Schafer, Zachary T

2017-07-01

Integrin-mediated attachment to the extracellular matrix (ECM) is required to combat the induction of programmed cell death in a variety of distinct cell types. If cells fail to maintain proper ECM attachment, they become subject to elimination via an apoptotic cell death program known as anoikis. However, anoikis inhibition is not sufficient to promote the long-term survival of ECM-detached cells. Several recent studies have unveiled the profound (anoikis-independent) impact of cell metabolism on the viability of ECM-detached cells. Thus, we posit that, during metastatic dissemination (when cancer cells are exposed to periods of ECM detachment), cancer cells must alter their metabolism in a fashion that promotes survival and ultimately contributes to metastatic outgrowth. Copyright © 2017 Elsevier Inc. All rights reserved.

Self-sustained detachment in the Large Helical Device

International Nuclear Information System (INIS)

Miyazawa, J.; Masuzaki, S.; Sakamoto, R.; Arimoto, H.; Kondo, K.; Tamura, N.; Shoji, M.; Nishiura, M.; Murakami, S.; Funaba, H.; Peterson, B.J.; Sakakibara, S.; Kobayashi, M.; Tanaka, K.; Narihara, K.; Yamada, I.; Morita, S.; Goto, M.; Osakabe, M.; Ashikawa, N.; Morisaki, T.; Nishimura, K.; Yamada, H.; Ohyabu, N.; Komori, A.; Motojima, O.

2006-01-01

Self-sustained detachment has been obtained in the Large Helical Device (LHD). Strong hydrogen gas puffing of ∼200 Pa m 3 s -1 after a density feedback phase detaches the plasma from the divertor plates with high reproducibility. High electron density of over 1 x 10 20 m -3 is sustained without gas puffing until the heating beam stops and a high-density flat top for 2 s has been demonstrated. Throughout the self-sustained detachment phase, the minor radius of the hot plasma column shrinks to ∼90% of the last-closed-flux-surface, which corresponds to the ι-bar ι/2π = 1/q =1 rational surface. This new state has been named the 'Serpens mode', for self-regulated plasma edge 'neath the last-closed-flux-surface. Global energy confinement of the Serpens mode is compared with the international stellarator scaling 1995 (ISS95) and the recently established scaling for high-density LHD plasmas (HD scaling), where shrinking confinement volume and shallow penetration of the heating beams are taken into account. Although the energy confinement of the Serpens mode seems deteriorated compared with ISS95, as in the case of high-density attached plasmas, it is consistent with the HD scaling. This suggests that the energy confinement properties of detached plasmas in LHD are similar to those in high-density attached plasmas

Postoperative recovery of visual function after macula-off rhegmatogenous retinal detachment.

Science.gov (United States)

van de Put, Mathijs A J; Croonen, Danna; Nolte, Ilja M; Japing, Wouter J; Hooymans, Johanna M M; Los, Leonoor I

2014-01-01

To determine which factors affect the recovery of visual function in macula off rhegmatogenous retinal detachment (RRD). In a prospective study of forty-five patients with a primary macula-off RRD of 24 hours to 6 weeks duration, the height of the macular detachment was determined by ultrasonography. At 12 months postoperatively, best corrected visual acuity (BCVA), contrast acuity, and color confusion indexes (CCI) were obtained. Macular detachment was present for 2-32 (median 7) days before repair. A shorter duration of macular detachment was correlated with a better CCI saturé (p = 0.0026) and lower LogMAR BCVA (better Snellen visual acuity) (p = 0.012). Also, a smaller height of macular detachment was correlated with a lower LogMAR BCVA (p = 0.0034). A younger age and lower pre-operative LogMAR BCVA at presentation were both correlated with better postoperative contrast acuity in the total group (age: p = 1.7×10(-4) and pre-operative LogMAR BCVA: p = 0.0034). Functional recovery after macula-off RRD is affected by the duration and the height of the macular detachment. Recovery of contrast acuity is also affected by age and BCVA at presentation. ARVO annual meeting 2013, May 7, Seattle, Washington, United States of America. trialregister.nl NTR839.

Inlet Flow Control and Prediction Technologies for Embedded Propulsion Systems

Science.gov (United States)

McMillan, Michelle L.; Mackie, Scott A.; Gissen, Abe; Vukasinovic, Bojan; Lakebrink, Matthew T.; Glezer, Ari; Mani, Mori; Mace, James L.

2011-01-01

Fail-safe, hybrid, flow control (HFC) is a promising technology for meeting high-speed cruise efficiency, low-noise signature, and reduced fuel-burn goals for future, Hybrid-Wing-Body (HWB) aircraft with embedded engines. This report details the development of HFC technology that enables improved inlet performance in HWB vehicles with highly integrated inlets and embedded engines without adversely affecting vehicle performance. In addition, new test techniques for evaluating Boundary-Layer-Ingesting (BLI)-inlet flow-control technologies developed and demonstrated through this program are documented, including the ability to generate a BLI-like inlet-entrance flow in a direct-connect, wind-tunnel facility, as well as, the use of D-optimal, statistically designed experiments to optimize test efficiency and enable interpretation of results. Validated improvements in numerical analysis tools and methods accomplished through this program are also documented, including Reynolds-Averaged Navier-Stokes CFD simulations of steady-state flow physics for baseline, BLI-inlet diffuser flow, as well as, that created by flow-control devices. Finally, numerical methods were employed in a ground-breaking attempt to directly simulate dynamic distortion. The advances in inlet technologies and prediction tools will help to meet and exceed "N+2" project goals for future HWB aircraft.

Microphysical Modeling of Titan's Detached Haze Layer in a 3D GCM

Science.gov (United States)

Larson, Erik J.; Toon, Owen B.; West, Robert A.; Friedson, A. James

2015-11-01

We investigate the formation and seasonal cycle of the detached haze layer in Titan’s upper atmosphere using a 3D GCM with coupled aerosol microphysics. The base of the detached haze layer is defined by a local minimum in the vertical extinction profile. The detached haze is seen at all latitudes including the south pole as seen in Cassini images from 2005-2012. The layer merges into the winter polar haze at high latitudes where the Hadley circulation carries the particles downward. The hemisphere in which the haze merges with the polar haze varies with season. We find that the base of the detached haze layer occurs where there is a near balance between vertical winds and particle fall velocities. Generally the vertical variation of particle concentration in the detached haze region is simply controlled by sedimentation, so the concentration and the extinction vary roughly in proportion to air density. This variation explains why the upper part of the main haze layer, and the bulk of the detached haze layer follow exponential profiles. However, the shape of the profile is modified in regions where the vertical wind velocity is comparable to the particle fall velocity. Our simulations closely match the period when the base of the detached layer in the tropics is observed to begin its seasonal drop in altitude, and the total range of the altitude drop. However, the simulations have the base of the detached layer about 100 km lower than observed, and the time for the base to descend is slower in the simulations than observed. These differences may point to the model having somewhat lower vertical winds than occur on Titan, or somewhat too large of particle sizes, or some combination of both. Our model is consistent with a dynamical origin for the detached haze rather than a chemical or microphysical one. This balance between the vertical wind and particle fall velocities occurs throughout the summer hemisphere and tropics. The particle concentration gradients that

A case of traction retinal detachment in a patient with Gaucher disease.

Science.gov (United States)

Watanabe, Akira; Gekka, Tamaki; Arai, Kota; Tsuneoka, Hiroshi

2017-01-01

This is the first report of vitreous surgery for traction retinal detachment in a patient with type III Gaucher disease with multiple vitreous opacities. A 16-year-old boy who was diagnosed with Gaucher disease at age two and was undergoing enzyme replacement therapy presented with numerous white opacities of varying sizes in the vitreous bodies of both eyes. Visual acuity was 20/40 in the right eye and 20/2000 in the left eye. The retina of the left eye was completely detached, and vitreous surgery was performed. Liquefaction of the vitreous body was advanced, and the central part of the vitreous cavity contained almost no vitreous humor. The macular region was successfully aspirated with a vitreous cutter to form a posterior vitreous detachment. From the optic disk to the nasal side, however, posterior vitreous detachment formation was prevented by strong adhesions between the retina and the vitreous body. The traction retinal detachment of the posterior fundus improved after vitreous body resection alone. Traction retinal detachment may occur as a result of severe vitreous liquefaction in cases of Gaucher disease with numerous vitreous opacities.

Calculation of external-internal flow fields for mixed-compression inlets

Science.gov (United States)

Chyu, W. J.; Kawamura, T.; Bencze, D. P.

1987-01-01

Supersonic inlet flows with mixed external-internal compressions were computed using a combined implicit-explicit (Beam-Warming-Steger/MacCormack) method for solving the three-dimensional unsteady, compressible Navier-Stokes equations in conservation form. Numerical calculations were made of various flows related to such inlet operations as the shock-wave intersections, subsonic spillage around the cowl lip, and inlet started versus unstarted conditions. Some of the computed results were compared with wind tunnel data.

Carbon distribution during plasma detachment triggered by edge magnetic island formation in LHD

International Nuclear Information System (INIS)

Dong, C.F.; Morita, S.; Kobayashi, M.; Oishi, T.; Goto, M.; Wang, E.H.; Huang, X.L.

2013-01-01

The detached plasma has been successfully achieved by applying the edge 1/1 magnetic island in Large Helical Device (LHD). Carbon, which is uniquely the dominant intrinsic impurity in general LHD discharges, is considered to be the main radiating species in the island-triggered detached plasma. The vertical profile of CIV measured from general discharges of LHD is characterized by a single edge intensity peak. In detached plasmas triggered by the edge magnetic island formation, however, the vertical profile of CIV shows a significant difference. Double edge peaks of CIV are found during the plasma detachment and the CIV radiation is also remarkably enhanced in the vicinity of X-point, whereas the vertical profile of CVI does not show any significant difference in both the attached and detached plasmas. In this proceeding the carbon distribution during the plasma detachment is presented and the results are discussed with edge magnetic field structure. (author)

Incidence and Pattern of Retinal Detachment in a Tertiary Eye ...

African Journals Online (AJOL)

Objectives: The aim was to determine the hospital incidence, pattern and clinical presentation of retinal detachment at the Guinness Eye Center, Onitsha, Nigeria. Materials and Methods: Case files of all retinal detachment patients seen at the Guinness Eye Center Onitsha between June 1997 and May 2012 were reviewed.

A new scaling for divertor detachment

Science.gov (United States)

Goldston, R. J.; Reinke, M. L.; Schwartz, J. A.

2017-05-01

The ITER design, and future reactor designs, depend on divertor ‘detachment,’ whether partial, pronounced or complete, to limit heat flux to plasma-facing components and to limit surface erosion due to sputtering. It would be valuable to have a measure of the difficulty of achieving detachment as a function of machine parameters, such as input power, magnetic field, major radius, etc. Frequently the parallel heat flux, estimated typically as proportional to P sep/R or P sep B/R, is used as a proxy for this difficulty. Here we argue that impurity cooling is dependent on the upstream density, which itself must be limited by a Greenwald-like scaling. Taking this into account self-consistently, we find the impurity fraction required for detachment scales dominantly as power divided by poloidal magnetic field. The absence of any explicit scaling with machine size is concerning, as P sep surely must increase greatly for an economic fusion system, while increases in the poloidal field strength are limited by coil technology and plasma physics. This result should be challenged by comparison with 2D divertor codes and with measurements on existing experiments. Nonetheless, it suggests that higher magnetic field, stronger shaping, double-null operation, ‘advanced’ divertor configurations, as well as alternate means to handle heat flux such as metallic liquid and/or vapor targets merit greater attention.

Evaluation of PM-10 commercial inlets for new surveillance air sampler

International Nuclear Information System (INIS)

Langer, G.

1986-01-01

The inlet for the present Rock Flats Plant surveillance sampler does not meet the new but still tentative PM-10 (<10-μm particle mass) criterion for sampling the hazardous fraction of airborne dust. Since this criterion relates mainly to non-radioactive emissions, DOE and EPA are presently in the process of promulgating emission guidelines specifically for non-reactor DOE nuclear facilities. The authors present approach is to select a commercial inlet and modify its, if necessary, to meet the PM-10 criterion, keeping in mind that they may have to recover the dust collected in the inlet. There is no EPA-approved PM-10 inlet design; instead, EPA issued a performance specification. As a nuclear operation, Rocky Flats has to sample continuously to ensure no period remains unmonitored, instead of every sixth day, as set forth by EPA for non-nuclear installations. During this study period, the authors developed an inlet evaluation methodology to meet the above, anticipated EPA requirements. Also, they started testing two potential inlets. 6 references, 2 figures, 1 table

Emotional detachment in psychopathy: Involvement of dorsal default-mode connections.

Science.gov (United States)

Sethi, Arjun; Gregory, Sarah; Dell'Acqua, Flavio; Periche Thomas, Eva; Simmons, Andy; Murphy, Declan G M; Hodgins, Sheilagh; Blackwood, Nigel J; Craig, Michael C

2015-01-01

Criminal psychopathy is defined by emotional detachment [Psychopathy Checklist - Revised (PCL-R) factor 1], and antisocial behaviour (PCL-R factor 2). Previous work has associated antisocial behaviour in psychopathy with abnormalities in a ventral temporo-amygdala-orbitofrontal network. However, little is known of the neural correlates of emotional detachment. Imaging studies have indicated that the 'default-mode network' (DMN), and in particular its dorsomedial (medial prefrontal - posterior cingulate) component, contributes to affective and social processing in healthy individuals. Furthermore, recent work suggests that this network may be implicated in psychopathy. However, no research has examined the relationship between psychopathy, emotional detachment, and the white matter underpinning the DMN. We therefore used diffusion tensor imaging (DTI) tractography in 13 offenders with psychopathy and 13 non-offenders to investigate the relationship between emotional detachment and the microstructure of white matter connections within the DMN. These included the dorsal cingulum (containing the medial prefrontal - posterior cingulate connections of the DMN), and the ventral cingulum (containing the posterior cingulate - medial temporal connections of the DMN). We found that fractional anisotropy (FA) was reduced in the left dorsal cingulum in the psychopathy group (p = .024). Moreover, within this group, emotional detachment was negatively correlated with FA in this tract portion bilaterally (left: r = -.61, p = .026; right: r = -.62, p = .023). These results suggest the importance of the dorsal DMN in the emotional detachment observed in individuals with psychopathy. We propose a 'dual-network' model of white matter abnormalities in the disorder, which incorporates these with previous findings. Copyright © 2014 Elsevier Ltd. All rights reserved.

Tidal and subtidal exchange flows at an inlet of the Wadden Sea

Science.gov (United States)

Valle-Levinson, Arnoldo; Stanev, Emil; Badewien, Thomas H.

2018-03-01

Observations of underway velocity profiles during complete spring and neap tidal cycles were used to determine whether the spatial structures of tidal and subtidal flows at a tidal inlet in a multiple-inlet embayment are consistent with those observed at single-inlet embayments. Measurements were obtained at the Otzumer Balje, one of the multiple inlets among the East Frisian Islands of the Wadden Sea. The 1.5 km-wide inlet displayed a bathymetric profile consisting of a channel ∼15 m deep flanked by tide observations spanned 36 h in the period May 11-12, 2011, while spring tide measurements exceeded 48 h from May 17 to May 19, 2011. Analysis of observations indicate that frictional effects from bathymetry molded tidal flows. Spatial distributions of semidiurnal tidal current amplitude and phase conform to those predicted by an analytical model for a basin with one inlet. Maximum semidiurnal flows appear at the surface in the channel, furthest away from bottom friction effects. Therefore, Otzumer Balje displays tidal hydrodynamics that are independent of the other inlets of the embayment. Subtidal exchange flows are laterally sheared, with residual inflow in the channel combined with outflow over shoals. The spatial distribution of these residual flows follow theoretical expectations of tidally driven flows interacting with bathymetry. Such distribution is similar to the tidal residual circulation at other inlets with only one communication to the ocean, suggesting that at subtidal scales the Otzumer Balje responds to tidal forcing independently of the other inlets.

Correlation of visual recovery with macular height in macula-off retinal detachments.

Science.gov (United States)

Mowatt, L; Tarin, S; Nair, R G; Menon, J; Price, N J

2010-02-01

To determine the relationship between the preoperative macular height of a macular detachment and visual outcome of the post retinal reattachment. Prospective case series of 26 patients who presented to the Wolverhampton Eye Infirmary with a primary rhegmatogenous macula-off retinal detachment. Macular detachment height was assessed by B-scan ultrasound (10 Mhz) in the seated and supine postures before surgery. Age, gender, duration of the detachment, type of surgery, preoperative (pre-op) and postoperative (post-op) visual acuities at 3 and 6 months and status of the fellow eye were noted. A total of 26 eyes of 26 patients (mean age: 61.4 years+/-15.56 SD) were recruited. The mean logMAR pre- and post-op visual acuities at 3 and 6 months were 1.5+/-1.1 SD (range: 0.2-3), 0.38+/-0.23 SD (range: 0-0.84), and at 6 months 0.29+/-0.22 SD (range: 0-1.0). The median period of the macular detachment was 4.5 days (95% CI: 2-8 days). There was no significant difference between the mean macular heights while seated 2.42 mm+/-1.2 or supine 2.39 mm+/-1.0 (t-test, P=0.9). Correlation showed that the pre-op macular height is a statistical predictor of post-op visual acuity in our group of patients with macula-off retinal detachments. The shallower the macular detachment the greater the likelihood of a good visual outcome.

Heat flux management via advanced magnetic divertor configurations and divertor detachment

Energy Technology Data Exchange (ETDEWEB)

Kolemen, E., E-mail: ekolemen@princeton.edu [Princeton University, Princeton, NJ 08544 (United States); Allen, S.L. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Bray, B.D. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Fenstermacher, M.E. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Humphreys, D.A.; Hyatt, A.W. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Lasnier, C.J. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Leonard, A.W. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Makowski, M.A.; McLean, A.G. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Maingi, R.; Nazikian, R. [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States); Petrie, T.W. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Soukhanovskii, V.A. [Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States); Unterberg, E.A. [Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, TN 37831 (United States)

2015-08-15

The snowflake divertor (SFD) control and detachment control to manage the heat flux at the divertor are successfully demonstrated at DIII-D. Results of the development and implementation of these two heat flux reduction control methods are presented. The SFD control algorithm calculates the position of the two null-points in real-time and controls shaping coil currents to achieve and stabilize various snowflake configurations. Detachment control stabilizes the detachment front fixed at specified distance between the strike point and the X-point throughout the shot.

Fasudil, a Clinically Used ROCK Inhibitor, Stabilizes Rod Photoreceptor Synapses after Retinal Detachment.

Science.gov (United States)

Townes-Anderson, Ellen; Wang, Jianfeng; Halász, Éva; Sugino, Ilene; Pitler, Amy; Whitehead, Ian; Zarbin, Marco

2017-06-01

Retinal detachment disrupts the rod-bipolar synapse in the outer plexiform layer by retraction of rod axons. We showed that breakage is due to RhoA activation whereas inhibition of Rho kinase (ROCK), using Y27632, reduces synaptic damage. We test whether the ROCK inhibitor fasudil, used for other clinical applications, can prevent synaptic injury after detachment. Detachments were made in pigs by subretinal injection of balanced salt solution (BSS) or fasudil (1, 10 mM). In some animals, fasudil was injected intravitreally after BSS-induced detachment. After 2 to 4 hours, retinae were fixed for immunocytochemistry and confocal microscopy. Axon retraction was quantified by imaging synaptic vesicle label in the outer nuclear layer. Apoptosis was analyzed using propidium iodide staining. For biochemical analysis by Western blotting, retinal explants, detached from retinal pigmented epithelium, were cultured for 2 hours. Subretinal injection of fasudil (10 mM) reduced retraction of rod spherules by 51.3% compared to control detachments ( n = 3 pigs, P = 0.002). Intravitreal injection of 10 mM fasudil, a more clinically feasible route of administration, also reduced retraction (28.7%, n = 5, P ROCK, was decreased with 30 μM fasudil ( n = 8-10 explants, P ROCK signaling with fasudil reduced photoreceptor degeneration and preserved the rod-bipolar synapse after retinal detachment. These results support the possibility, previously tested with Y27632, that ROCK inhibition may attenuate synaptic damage in iatrogenic detachments.

The fellow eye of patients with phakic lattice retinal detachment.

Science.gov (United States)

Folk, J C; Arrindell, E L; Klugman, M R

1989-01-01

A retrospective study was performed to determine whether the prophylactic treatment of areas of lattice degeneration, holes, or breaks reduced the risk of subsequent new breaks or detachment in the fellow undetached phakic eyes of patients with a phakic lattice retinal detachment (RD). Three hundred eighty-eight consecutive patients who presented to the University of Iowa between 1959 and 1984 were followed for a mean of 7.9 +/- 5.8 years after the detachment in the first eye. Fellow eyes which received no prophylactic treatment had a 2.5 times greater risk of a new break or RD over 7 years than eyes receiving full prophylactic treatment (19.4 versus 7.5%; P = 0.0002). Fellow eyes receiving no treatment also had a greater risk of a new RD over 7 years than eyes receiving full treatment (5.1 versus 1.8%; P = 0.0125). These results do not allow us to make recommendations concerning which fellow eyes, if any, should be prophylactically treated. On the one hand, prophylactic treatment did significantly reduce the risk of new breaks and detachments. On the other hand, however, prophylactic treatment reduced the risk of new RD alone in the fellow eye only from 5.1 to 1.8% over 7 years. In addition, prophylactic treatment did not reduce the risk of detachment in the higher risk eyes with high myopia or extensive lattice.

Validation of helium inlet design for ITER toroidal field coil

International Nuclear Information System (INIS)

Boyer, C.; Seo, K.; Hamada, K.; Foussat, A.; Le Rest, M.; Mitchell, N.; Decool, P.; Savary, F.; Sgobba, S.; Weiss, K.P.

2014-01-01

The ITER organization has performed design and its validation tests on a helium inlet structure for the ITER Toroidal Field (TF) coil under collaboration with CERN, KIT, and CEA Cadarache. Detailed structural analysis was performed in order to optimize the weld shape. A fatigue resistant design on the fillet weld between the shell covers and the jacket is an important point on the helium inlet structure. A weld filler material was selected based on tensile test at liquid helium temperature after Nb 3 Sn reaction heat treatment. To validate the design of the weld joint, fatigue tests at 7 K were performed using heat-treated butt weld samples. A pressure drop measurement of a helium inlet mock-up was performed by using nitrogen gas at room temperature in order to confirm uniform flow distribution and pressure drop characteristic. These tests have validated the helium inlet design. Based on the validation, Japanese and European Union domestic agencies, which have responsibilities of the TF coil procurement, are preparing the helium inlet mock-up for a qualification test. (authors)

On the use of purchased fuelwood in detached houses in Finland

International Nuclear Information System (INIS)

Tuomi, S.; Mattila, K.

1996-01-01

The study, conducted jointly by the Finnish Forest Research Institute (METLA) and the Work Efficiency Institute (TTS-Institute), looked into the volumes of fuelwood consumed by, the manner of fuel wood procurement employed, and the usage plans of people living in detached houses. The study was conducted during the heating season 1992/93. METLA collected the study material by the means of a nation-wide mail inquiry. The base population for the study was provided by all the 1.4 million detached houses in Finland. The sample comprised 12 273 detached houses. This publication of the Forestry Department of TTS-Institute is a separate report on the use of fuelwood and other issues related to purchased fuelwood. An estimated total of 5.6 million m 3 of fuelwood were consumed in by household living in detached houses throughout Finland during the heating season 1992/93. The consumption of fuelwood on farms was 2.5 million m 3 , in detached houses proper 2.3 million m 3 , in recreational homes 0.6 million m 3 , and other houses 0.2 million m 3 . 3.6 million m 3 of the fuelwood consumed was acquired from the users' own woodlots. The proportion of purchased wood was nearly a million m 3 and another million m 3 of fuelwood were acquired by some other way. Of the purchased fuelwood, 12 % was bought ready- chopped. More than one owner of detached houses considered the use of purchased wood a possibility. Ready-chopped firewood was the most popular form of fuelwood. The owners of nearly 220 000 detached houses planned to increase their fuelwood consumption during the next two years and 27 % of them intended to buy their fuelwood. 11 % of the respondents were of the opinion that there was not enough purchased fuelwood in suitable form available in their locality. (19 refs.)

Organics Verification Study for Sinclair and Dyes Inlets, Washington

Energy Technology Data Exchange (ETDEWEB)

Kohn, Nancy P.; Brandenberger, Jill M.; Niewolny, Laurie A.; Johnston, Robert K.

2006-09-28

Sinclair and Dyes Inlets near Bremerton, Washington, are on the State of Washington 1998 303(d) list of impaired waters because of fecal coliform contamination in marine water, metals in sediment and fish tissue, and organics in sediment and fish tissue. Because significant cleanup and source control activities have been conducted in the inlets since the data supporting the 1998 303(d) listings were collected, two verification studies were performed to address the 303(d) segments that were listed for metal and organic contaminants in marine sediment. The Metals Verification Study (MVS) was conducted in 2003; the final report, Metals Verification Study for Sinclair and Dyes Inlets, Washington, was published in March 2004 (Kohn et al. 2004). This report describes the Organics Verification Study that was conducted in 2005. The study approach was similar to the MVS in that many surface sediment samples were screened for the major classes of organic contaminants, and then the screening results and other available data were used to select a subset of samples for quantitative chemical analysis. Because the MVS was designed to obtain representative data on concentrations of contaminants in surface sediment throughout Sinclair Inlet, Dyes Inlet, Port Orchard Passage, and Rich Passage, aliquots of the 160 MVS sediment samples were used in the analysis for the Organics Verification Study. However, unlike metals screening methods, organics screening methods are not specific to individual organic compounds, and are not available for some target organics. Therefore, only the quantitative analytical results were used in the organics verification evaluation. The results of the Organics Verification Study showed that sediment quality outside of Sinclair Inlet is unlikely to be impaired because of organic contaminants. Similar to the results for metals, in Sinclair Inlet, the distribution of residual organic contaminants is generally limited to nearshore areas already within the

Impeller inlet geometry effect on performance improvement for centrifugal pumps

International Nuclear Information System (INIS)

Luo, Xianwu; Zhang, Yao; Peng, Junqi; Xu, Hongyuan; Yu, Weiping

2008-01-01

This research treats the effect of impeller inlet geometry on performance improvement for a boiler feed pump, who is a centrifugal pump having specific speed of 183 m.m 3 min -1 .min -1 and close type impeller with exit diameter of 450 mm. The hydraulic performance and cavitation performance of the pump have been tested experimentally. In order to improve the pump, five impellers have been considered by extending the blade leading edge or applying much larger blade angle at impeller inlet compared with the original impeller. The 3-D turbulent flow inside those pumps has been analyzed basing on RNG k-ε turbulence model and VOF cavitation model. It is noted that the numerical results are fairly good compared with the experiments. Based on the experimental test and numerical simulation, the following conclusions can be drawn: (1) Impeller inlet geometry has important influence on performance improvement in the case of centrifugal pump. Favorite effects on performance improvement have been achieved by both extending the blade leading edge and applying much larger blade angle at impeller inlet: (2) It is suspected that the extended leading edge have favorite effect for improving hydraulic performance, and the much larger blade angle at impeller inlet have favorite effect for improving cavitation performance for the test pump: (3) Uniform flow upstream of impeller inlet is helpful for improving cavitation performance of the pump

Effect of a dual inlet channel on cell loading in microfluidics.

Science.gov (United States)

Yun, Hoyoung; Kim, Kisoo; Lee, Won Gu

2014-11-01

Unwanted sedimentation and attachment of a number of cells onto the bottom channel often occur on relatively large-scale inlets of conventional microfluidic channels as a result of gravity and fluid shear. Phenomena such as sedimentation have become recognized problems that can be overcome by performing microfluidic experiments properly, such as by calculating a meaningful output efficiency with respect to real input. Here, we present a dual-inlet design method for reducing cell loss at the inlet of channels by adding a new " upstream inlet " to a single main inlet design. The simple addition of an upstream inlet can create a vertically layered sheath flow prior to the main inlet for cell loading. The bottom layer flow plays a critical role in preventing the cells from attaching to the bottom of the channel entrance, resulting in a low possibility of cell sedimentation at the main channel entrance. To provide proof-of-concept validation, we applied our design to a microfabricated flow cytometer system (μFCS) and compared the cell counting efficiency of the proposed μFCS with that of the previous single-inlet μFCS and conventional FCS. We used human white blood cells and fluorescent microspheres to quantitatively evaluate the rate of cell sedimentation in the main inlet and to measure fluorescence sensitivity at the detection zone of the flow cytometer microchip. Generating a sheath flow as the bottom layer was meaningfully used to reduce the depth of field as well as the relative deviation of targets in the z-direction (compared to the x-y flow plane), leading to an increased counting sensitivity of fluorescent detection signals. Counting results using fluorescent microspheres showed both a 40% reduction in the rate of sedimentation and a 2-fold higher sensitivity in comparison with the single-inlet μFCS. The results of CD4(+) T-cell counting also showed that the proposed design results in a 25% decrease in the rate of cell sedimentation and a 28% increase in

Scleral buckling for retinal detachment in patients with retinoblastoma

International Nuclear Information System (INIS)

Buzney, S.M.; Pruett, R.C.; Regan, C.D.; Walton, D.S.; Smith, T.R.

1984-01-01

Three children (two girls and one boy) with bilateral retinoblastoma each developed a presumed rhegmatogenous retinal detachment in one eye. All three eyes had previously received radiation and cryotherapy. In each case the retinal detachment responded promptly to conventional surgical methods via scleral buckling in the area of treated retinoblastoma and presumed retinal break. All three eyes have retained useful vision for follow-up periods of 3.5 to 12 years

Scleral buckling for retinal detachment in patients with retinoblastoma

Energy Technology Data Exchange (ETDEWEB)

Buzney, S.M.; Pruett, R.C.; Regan, C.D.; Walton, D.S.; Smith, T.R.

1984-10-15

Three children (two girls and one boy) with bilateral retinoblastoma each developed a presumed rhegmatogenous retinal detachment in one eye. All three eyes had previously received radiation and cryotherapy. In each case the retinal detachment responded promptly to conventional surgical methods via scleral buckling in the area of treated retinoblastoma and presumed retinal break. All three eyes have retained useful vision for follow-up periods of 3.5 to 12 years.

Recombination dominated hydrogenic emission from the detached plasmas in W7-AS

International Nuclear Information System (INIS)

Ramasubramanian, N.; Koenig, R.; Wenzel, U.; Thomsen, H.; McCormick, K.; Grigull, P.; Feng, Y.; Klinger, T.; John, A.

2003-01-01

Beyond a certain threshold average density in the High-Density H-Mode the island divertor plasma in the stellarator W7-AS undergoes partial detachment. The tomographic reconstruction of the radiated power density from the detached pulses show that the radiation profile in the triangular plane is also asymmetric. In the detached phase, the spectrometer viewing tangentially to the target tiles in the top divertor region manifests that the impurity radiation layer is close to the X-points. The spectral analysis also demonstrates the presence of a hydrogen radiation zone dominated by recombination emission close to the target tiles. This papers presents the emission from the deeply detached locations including the volume recombination in a stable discharge. (orig.)

Background-Oriented Schlieren used in a hypersonic inlet test at NASA GRC

Science.gov (United States)

Clem, Michelle; Woike, Mark; Saunders, John

2016-01-01

Background Oriented Schlieren (BOS) is a derivative of the classical schlieren technology, which is used to visualize density gradients, such as shock wave structures in a wind tunnel. Changes in refractive index resulting from density gradients cause light rays to bend, resulting in apparent motion of a random background pattern. The apparent motion of the pattern is determined using cross-correlation algorithms (between no-flow and with-flow image pairs) producing a schlieren-like image. One advantage of BOS is its simplified setup which enables a larger field-of-view (FOV) than traditional schlieren systems. In the present study, BOS was implemented into the Combined Cycle Engine Large-Scale Inlet Mode Transition Experiment (CCE LIMX) in the 10x10 Supersonic Wind Tunnel at NASA Glenn Research Center. The model hardware for the CCE LIMX accommodates a fully integrated turbine based combined cycle propulsion system. To date, inlet mode transition between turbine and ramjet operation has been successfully demonstrated. High-speed BOS was used to visualize the behavior of the flow structures shock waves during unsteady inlet unstarts, a phenomenon known as buzz. Transient video images of inlet buzz were recorded for both the ramjet flow path (high speed inlet) and turbine flow path (low speed inlet). To understand the stability limits of the inlet, operation was pushed to the point of unstart and buzz. BOS was implemented in order to view both inlets simultaneously, since the required FOV was beyond the capability of the current traditional schlieren system. An example of BOS data (Images 1-6) capturing inlet buzz are presented.

33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a) Explosives...

Long time durability tests of fabric inlet stratification pipes

DEFF Research Database (Denmark)

Andersen, Elsa; Furbo, Simon

2008-01-01

and that this destroys the capability of building up thermal stratification for the fabric inlet stratification pipe. The results also show that although dirt, algae etc. are deposited in the fabric pipes in the space heating tank, the capability of the fabric inlet stratifiers to build up thermal stratification...

Rhegmatogenous retinal detachment following intravitreal ocriplasmin

NARCIS (Netherlands)

Madi, Haifa A.; Haynes, Richard J.; Depla, Diana; de la Cour, Morten D.; Lesnik-Oberstein, Sarit; Muqit, Mahi M. K.; Patton, Niall; Price, Nick; Steel, David H. W.

2016-01-01

To describe the characteristics and outcomes of patients presenting with rhegmatogenous retinal detachment (RRD) after ocriplasmin (OCP) injection. Retrospective, multi-centre, observational case series with case note review. Eight patients with symptomatic vitreomacular traction (six with

Modelling Morphological Response of Large Tidal Inlet Systems to Sea Level Rise

NARCIS (Netherlands)

Dissanayake, P.K.

2011-01-01

This dissertation qualitatively investigates the morphodynamic response of a large inlet system to IPCC projected relative sea level rise (RSLR). Adopted numerical approach (Delft3D) used a highly schematised model domain analogous to the Ameland inlet in the Dutch Wadden Sea. Predicted inlet

Flow Control in a Compact Inlet

Science.gov (United States)

Vaccaro, John C.

2011-12-01

An experimental investigation of flow control, via various control jets actuators, was undertaken to eliminate separation and secondary flows in a compact inlet. The compact inlet studied was highly aggressive with a length-to-diameter ratio of 1.5. A brand new facility was designed and built to enable various actuation methodologies as well as multiple measurement techniques. Techniques included static surface pressure, total pressure, and stereoscopic particle image velocimetry. Experimental data were supplemented with numerical simulations courtesy of Prof. Kenneth Jansen, Dr. Onkar Sahni, and Yi Chen. The baseline flow field was found to be dominated by two massive separations and secondary flow structures. These secondary structures were present at the aerodynamic interface plane in the form of two counter-rotating vortices inducing upwash along centerline. A dominant shedding frequency of 350 Hz was measured both at the aerodynamic interface plane and along the lower surface of the inlet. Flow control experiments started utilizing a pair of control jets placed in streamwise locations where flow was found to separate. Tests were performed for a range of inlet Mach numbers from 0.2 to 0.44. Steady and unsteady static pressure measurements along the upper and lower walls of the duct were performed for various combinations of actuation. The parameters that were tested include the control jets momentum coefficient, their blowing ratio, the actuation frequency, as well as different combinations of jets. It was shown that using mass flux ratio as a criterion to define flow control is not sufficient, and one needs to provide both the momentum coefficient and the blowing ratio to quantify the flow control performance. A detailed study was undertaken on controlling the upstream separation point for an inlet Mach number of 0.44. Similar to the baseline flow field, the flow field associated with the activation of a two-dimensional control jet actuator was dominated by

Effect of the inlet throttling on the thermal-hydraulic instability of the natural circulation BWR

International Nuclear Information System (INIS)

Furuya, Masahiro; Inada, Fumio; Yoneda, Kimitoshi

1997-01-01

Although it is well-established that inlet restriction has a stabilizing for forced circulation BWR, the effect of inlet on the thermal-hydraulic stability of natural circulation BWR remains unknown since increasing inlet restriction affect thermal-hydraulic stability due to reduction of the recirculation flow rate. Therefore experiments have been conducted to investigate the effect of inlet restriction on the thermal-hydraulic stability. A test facility used in this experiments was designed and constructed to have non-dimensional values which are nearly equal to those of natural circulation BWR. Experimental results showed that driving force of the natural circulation was described as a function of heat flux and inlet subcooling independent of inlet restriction. Stability maps in reference to the channel inlet subcooling, heat flux were presented for various inlet restriction which were carried out by an analysis based on the homogeneous flow various using this function. Instability region during the inlet subcooling shifted to the higher inlet subcooling with increasing inlet restriction and became larger with increasing heat flux. (author)

Should we attempt global (inlet engine airframe) control design?

Science.gov (United States)

Carlin, C. M.

1980-01-01

The feasibility of multivariable design of the entire airplane control system is briefly addressed. An intermediate step in that direction is to design a control for an inlet engine augmentor system by using multivariable techniques. The supersonic cruise large scale inlet research program is described which will provide an opportunity to develop, integrate, and wind tunnel test a control for a mixed compression inlet and variable cycle engine. The integrated propulsion airframe control program is also discussed which will introduce the problem of implementing MVC within a distributed processing avionics architecture, requiring real time decomposition of the global design into independent modules in response to hardware communication failures.

Turbulent Simulations of Divertor Detachment Based On BOUT + + Framework

Science.gov (United States)

Chen, Bin; Xu, Xueqiao; Xia, Tianyang; Ye, Minyou

2015-11-01

China Fusion Engineering Testing Reactor is under conceptual design, acting as a bridge between ITER and DEMO. The detached divertor operation offers great promise for a reduction of heat flux onto divertor target plates for acceptable erosion. Therefore, a density scan is performed via an increase of D2 gas puffing rates in the range of 0 . 0 ~ 5 . 0 ×1023s-1 by using the B2-Eirene/SOLPS 5.0 code package to study the heat flux control and impurity screening property. As the density increases, it shows a gradually change of the divertor operation status, from low-recycling regime to high-recycling regime and finally to detachment. Significant radiation loss inside the confined plasma in the divertor region during detachment leads to strong parallel density and temperature gradients. Based on the SOLPS simulations, BOUT + + simulations will be presented to investigate the stability and turbulent transport under divertor plasma detachment, particularly the strong parallel gradient driven instabilities and enhanced plasma turbulence to spread heat flux over larger surface areas. The correlation between outer mid-plane and divertor turbulence and the related transport will be analyzed. Prepared by LLNL under Contract DE-AC52-07NA27344. LLNL-ABS-675075.

Peripheral retinal degenerations and the risk of retinal detachment.

Science.gov (United States)

Lewis, Hilel

2003-07-01

To review the degenerative diseases of the peripheral retina in relationship with the risk to develop a rhegmatogenous retinal detachment and to present recommendations for use in eyes at increased risk of developing a retinal detachment. Focused literature review and author's clinical experience. Retinal degenerations are common lesions involving the peripheral retina, and most of them are clinically insignificant. Lattice degeneration, degenerative retinoschisis, cystic retinal tufts, and, rarely, zonular traction tufts, can result in a rhegmatogenous retinal detachment. Therefore, these lesions have been considered for prophylactic therapy; however, adequate studies have not been performed to date. Well-designed, prospective, randomized clinical studies are necessary to determine the benefit-risk ratio of prophylactic treatment. In the meantime, the evidence available suggests that most of the peripheral retinal degenerations should not be treated except in rare, high-risk situations.

Protein changes in the retina following experimental retinal detachment in rabbits

DEFF Research Database (Denmark)

Mandal, Nakul; Lewis, Geoffrey P.; Fisher, Steven K.

2011-01-01

Retinal detachment leads to the widespread cellular remodeling of the retina. The purpose of this study was to identify protein changes that accompany these cellular alterations by comparing the proteomic profiles of sham and experimentally detached rabbit retina. Elucidation of the proteins most...

Energy efficient air inlet humidity control; Energiezuinige inblaasvochtregeling

Energy Technology Data Exchange (ETDEWEB)

Gielen, J.H. [C Point, DLV Plant, Horst (Netherlands)

2005-03-15

This project report describes the results of research conducted on the control of the inlet, humidification and dehumidification, based on the air inlet humidity rate. The project was carried out at a mushroom cultivation business in Heijen, the Netherlands [Dutch] Deze projectrapportage geeft de resultaten van het onderzoek naar het regelen van de luchtklep, bevochtiging en ontvochtiging, op basis van het inblaasvochtgehalte. Het project werd uitgevoerd op een champignonkwekerij in Heijen.

Dissecting the roles of ROCK isoforms in stress-induced cell detachment.

Science.gov (United States)

Shi, Jianjian; Surma, Michelle; Zhang, Lumin; Wei, Lei

2013-05-15

The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1(-/-) and ROCK2(-/-) mice, we have recently reported that they play different roles in regulating doxorubicin-induced stress fiber disassembly and cell detachment: ROCK1 is involved in destabilizing the actin cytoskeleton and cell detachment, whereas ROCK2 is required for stabilizing the actin cytoskeleton and cell adhesion. Here, we present additional insights into the roles of ROCK1 and ROCK2 in regulating stress-induced impairment of cell-matrix and cell-cell adhesion. In response to doxorubicin, ROCK1(-/-) MEFs showed significant preservation of both focal adhesions and adherens junctions, while ROCK2(-/-) MEFs exhibited impaired focal adhesions but preserved adherens junctions compared with the wild-type MEFs. Additionally, inhibition of focal adhesion or adherens junction formations by chemical inhibitors abolished the anti-detachment effects of ROCK1 deletion. Finally, ROCK1(-/-) MEFs, but not ROCK2(-/-) MEFs, also exhibited preserved central stress fibers and reduced cell detachment in response to serum starvation. These results add new insights into a novel mechanism underlying the anti-detachment effects of ROCK1 deletion mediated by reduced peripheral actomyosin contraction and increased actin stabilization to promote cell-cell and cell-matrix adhesion. Our studies further support the differential roles of ROCK isoforms in regulating stress-induced loss of central stress fibers and focal adhesions as well as cell detachment.

Bilateral patching in retinal detachment: fluid mechanics and retinal "settling".

Science.gov (United States)

Foster, William J

2011-07-20

When a patient suffers a retinal detachment and surgery is delayed, it is known clinically that bilaterally patching the patient may allow the retina to partially reattach or "settle." Although this procedure has been performed since the 1860s, there is still debate as to how such a maneuver facilitates the reattachment of the retina. Finite element calculations using commercially available analysis software are used to elucidate the influence of reduction in eye movement caused by bilateral patching on the flow of subretinal fluid in a physical model of retinal detachment. It was found that by coupling fluid mechanics with structural mechanics, a physically consistent explanation of increased retinal detachment with eye movements can be found in the case of traction on the retinal hole. Large eye movements increase vitreous traction and detachment forces on the edge of the retinal hole, creating a subretinal vacuum and facilitating increased subretinal fluid. Alternative models, in which intraocular fluid flow is redirected into the subretinal space, are not consistent with these simulations. The results of these simulations explain the physical principles behind bilateral patching and provide insight that can be used clinically. In particular, as is known clinically, bilateral patching may facilitate a decrease in the height of a retinal detachment. The results described here provide a description of a physical mechanism underlying this technique. The findings of this study may aid in deciding whether to bilaterally patch patients and in counseling patients on pre- and postoperative care.

Interactions Between Wetlands and Tidal Inlets

National Research Council Canada - National Science Library

Sanchez, Alejandro

2008-01-01

This Coastal and Hydraulics Engineering Technical Note (CHETN) presents numerical simulations investigating how the loss of wetlands in estuaries modifies tidal processes in inlet navigation channels...

Impeller inlet geometry effect on performance improvement for centrifugal pumps

Energy Technology Data Exchange (ETDEWEB)

Luo, Xianwu; Zhang, Yao; Peng, Junqi; Xu, Hongyuan [Tsinghua University, Beijing (China); Yu, Weiping [Zhejiang Pump Works, Zhejiang (China)

2008-10-15

This research treats the effect of impeller inlet geometry on performance improvement for a boiler feed pump, who is a centrifugal pump having specific speed of 183 m.m{sup 3}min{sup -1}.min{sup -1} and close type impeller with exit diameter of 450 mm. The hydraulic performance and cavitation performance of the pump have been tested experimentally. In order to improve the pump, five impellers have been considered by extending the blade leading edge or applying much larger blade angle at impeller inlet compared with the original impeller. The 3-D turbulent flow inside those pumps has been analyzed basing on RNG k-{epsilon} turbulence model and VOF cavitation model. It is noted that the numerical results are fairly good compared with the experiments. Based on the experimental test and numerical simulation, the following conclusions can be drawn: (1) Impeller inlet geometry has important influence on performance improvement in the case of centrifugal pump. Favorite effects on performance improvement have been achieved by both extending the blade leading edge and applying much larger blade angle at impeller inlet: (2) It is suspected that the extended leading edge have favorite effect for improving hydraulic performance, and the much larger blade angle at impeller inlet have favorite effect for improving cavitation performance for the test pump: (3) Uniform flow upstream of impeller inlet is helpful for improving cavitation performance of the pump

Physics of Acoustic Radiation from Jet Engine Inlets

Science.gov (United States)

Tam, Christopher K. W.; Parrish, Sarah A.; Envia, Edmane; Chien, Eugene W.

2012-01-01

Numerical simulations of acoustic radiation from a jet engine inlet are performed using advanced computational aeroacoustics (CAA) algorithms and high-quality numerical boundary treatments. As a model of modern commercial jet engine inlets, the inlet geometry of the NASA Source Diagnostic Test (SDT) is used. Fan noise consists of tones and broadband sound. This investigation considers the radiation of tones associated with upstream propagating duct modes. The primary objective is to identify the dominant physical processes that determine the directivity of the radiated sound. Two such processes have been identified. They are acoustic diffraction and refraction. Diffraction is the natural tendency for an acoustic wave to follow a curved solid surface as it propagates. Refraction is the turning of the direction of propagation of sound waves by mean flow gradients. Parametric studies on the changes in the directivity of radiated sound due to variations in forward flight Mach number and duct mode frequency, azimuthal mode number, and radial mode number are carried out. It is found there is a significant difference in directivity for the radiation of the same duct mode from an engine inlet when operating in static condition and in forward flight. It will be shown that the large change in directivity is the result of the combined effects of diffraction and refraction.

Evaluation of magnetic resonance imaging in thoracic inlet tumors

Energy Technology Data Exchange (ETDEWEB)

Sakai, Eiro (Kobe Univ. (Japan). School of Medicine)

1993-06-01

To evaluate the detectability of tumor invasion to the thoracic inlet, MRI was performed in 57 patients with thoracic inlet tumor, and the diagnostic accuracy of MRI was compared with that of CT concerning the utility for thoracic inlet lesions. And we assessed abnormal findings in comparison with surgical or autopsy findings. In the local extent of the tumor, the accuracy for tumor invasion to the vessels such as subclavian artery and vein was 94.9% for MRI, and 83.5% for CT, and to the brachial plexus was 95.0% for MRI, and 60.0% for CT. MRI was superior to CT, but MRI was equivalent to CT with regard to invasion to the base of the neck, lateral chest wall, ribs, and vertebral bodies. However on MRI, it is easier to understand the longitudinal tumor extent than on CT. CT has superior spatial resolusion but CT has also disadvantages, such as streak artifact caused by shoulder joints, resulting in image degradation. In contrast, MRI has inherent advantages, and multiple images which facilitate the relationship between tumor and normal structures. Coronal and sagittal MR images facilitated three-dimensional observation of tumor of invasion in the thoracic inlet. Furthermore to improve image quality of MRI for the thoracic inlet, we newly devised a high molecular polyester shell for fixing a surface coil. On the high resolution MR (HR-MR) imaging using our shell, normal lymph nodes, muscles, blood vessels and the branches of the branchial plexus were clearly visualized in detail. Our shell was simple to process and facilitated immobilization of a surface coil. HR-MR technique produces images of high resolution after simple preparation. In conclusion, MRI was very useful for detecting lesions of the thoracic inlet and in deciding surgical indication and the planning for radiotherapy. (author).

Can barrier islands survive sea level rise? Tidal inlets versus storm overwash

Science.gov (United States)

Nienhuis, J.; Lorenzo-Trueba, J.

2017-12-01

Barrier island response to sea level rise depends on their ability to transgress and move sediment to the back barrier, either through flood-tidal delta deposition or via storm overwash. Our understanding of these processes over decadal to centennial timescales, however, is limited and poorly constrained. We have developed a new barrier inlet environment (BRIE) model to better understand the interplay between tidal dynamics, overwash fluxes, and sea-level rise on barrier evolution. The BRIE model combines existing overwash and shoreface formulations [Lorenzo-Trueba and Ashton, 2014] with alongshore sediment transport, inlet stability [Escoffier, 1940], inlet migration and flood-tidal delta deposition [Nienhuis and Ashton, 2016]. Within BRIE, inlets can open, close, migrate, merge with other inlets, and build flood-tidal delta deposits. The model accounts for feedbacks between overwash and inlets through their mutual dependence on barrier geometry. Model results suggest that when flood-tidal delta deposition is sufficiently large, barriers require less storm overwash to transgress and aggrade during sea level rise. In particular in micro-tidal environments with asymmetric wave climates and high alongshore sediment transport, tidal inlets are effective in depositing flood-tidal deltas and constitute the majority of the transgressive sediment flux. Additionally, we show that artificial inlet stabilization (via jetty construction or maintenance dredging) can make barrier islands more vulnerable to sea level rise. Escoffier, F. F. (1940), The Stability of Tidal Inlets, Shore and Beach, 8(4), 114-115. Lorenzo-Trueba, J., and A. D. Ashton (2014), Rollover, drowning, and discontinuous retreat: Distinct modes of barrier response to sea-level rise arising from a simple morphodynamic model, J. Geophys. Res. Earth Surf., 119(4), 779-801, doi:10.1002/2013JF002941. Nienhuis, J. H., and A. D. Ashton (2016), Mechanics and rates of tidal inlet migration: Modeling and application to

Effects of temporal muscle detachment and coronoidotomy on facial growth in young rats

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Fernanda Engelberg Fernandes Gomes

2012-08-01

Full Text Available This study analyzed the effects of unilateral detachment of the temporal muscle and coronoidotomy on facial growth in young rats. Thirty one-month-old Wistar rats were distributed into three groups: detachment, coronoidotomy and sham-operated. Under general anesthesia, unilateral detachment of the temporal muscle was performed for the detachment group, unilateral coronoidotomy was performed for the coronoidotomy group, and only surgical access was performed for the sham-operated group. The animals were sacrificed at three months of age. Their soft tissues were removed, and the mandible was disarticulated. Radiographic projections-axial views of the skulls and lateral views of hemimandibles-were taken. Cephalometric evaluations were performed, and the values obtained were submitted to statistical analyses. There was a significant homolateral difference in the length of the premaxilla, height of the mandibular ramus and body, and the length of the mandible in all three groups. However, comparisons among the groups revealed no significant differences between the detachment and coronoidotomy groups for most measurements. It was concluded that both experimental detachment of the temporal muscle and coronoidotomy during the growth period in rats induced asymmetry of the mandible and affected the premaxilla.

Phakic retinal detachment associated with atrophic hole of lattice degeneration of the retina.

Science.gov (United States)

Murakami-Nagasako, F; Ohba, N

1983-01-01

Forty patients with phakic nontraumatic retinal detachment caused by atrophic retinal hole of lattice degeneration were reviewed. The condition was characterized by insidious, slowly developing shallow detachment, with frequent formation of demarcation lines. Often, the patients did not recognize their visual problems until the detachment had extended to the macular region. Young patients under 40 years of age were more common than older patients. Myopic refractive errors were frequently associated. The results of surgical repair were favorable. The risk of retinal detachment in lattice degeneration with atrophic holes was estimated to be about 1 in 90 patients, and prophylactic treatment for this common anomaly is not readily recommended.

A numerical study of plasma detachment conditions in JET divertor plasmas

Energy Technology Data Exchange (ETDEWEB)

Simonini, R; Corrigan, G; Radford, G; Spence, J; Taroni, A; Weber, S [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking

1994-07-01

Simulation results obtained with the EDGE2D/U code confirm that for a given particle inventory in the SOL (including the divertor), the main parameter determining whether or not particle, momentum and energy detachment occurs, is the residual power P - P{sub lost}, where P is the total power entering the SOL and P{sub lost} is the power lost by transport to walls and by volume losses in the SOL outside the region where detachment takes place. For particle contents leading to reasonable values of the separatrix mid-plane density, detachment is found if the residual power is low enough. Typically the residual power must be inferior to 3 MW for good detachment, with the exact value depending on the geometry of the divertor, the transport assumptions and the neutral recirculation scheme. The results show that divertor plasma conditions relevant for the study of power exhaust and impurity control problems are possible in JET. 9 refs., 2 figs., 1 tab.

Massive Bilateral Serous Retinal Detachment in a Case of Hypertensive Chorioretinopathy

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Luis Villalba-Pinto

2014-07-01

Full Text Available Introduction: Systemic high blood pressure is related to a variety of retinal manifestations. We present an atypical case of hypertensive chorioretinopathy with massive bilateral serous retinal detachment. Case Report: A 26-year-old male with a genitourinary malformation and secondary grade IV chronic kidney failure as well as high blood pressure complained of acute vision loss. Dilated fundus examination evidenced a bilateral serous retinal detachment with macular involvement. The patient was unresponsive to oral antihypertensive therapy and dialysis treatment. The serous retinal detachment progressively decreased after the restoration of dialysis and antihypertensive therapy. The final visual acuity was 0.50 in both eyes. Discussion: In cases of serous macular detachment, it is mandatory to rule out different systemic and ocular diseases. The presence of uncontrolled high blood pressure may produce aggressive bilateral retinal changes, thus hypertension must be under early and strict control in order to improve the visual outcomes.

Massive Bilateral Serous Retinal Detachment in a Case of Hypertensive Chorioretinopathy

Science.gov (United States)

Villalba-Pinto, Luis; Hernández-Ortega, M. Ángeles; de los Mozos, F. Javier Lavid; Pascual-Camps, Isabel; Dolz-Marco, Rosa; Arevalo, J. Fernando; Gallego-Pinazo, Roberto

2014-01-01

Introduction Systemic high blood pressure is related to a variety of retinal manifestations. We present an atypical case of hypertensive chorioretinopathy with massive bilateral serous retinal detachment. Case Report A 26-year-old male with a genitourinary malformation and secondary grade IV chronic kidney failure as well as high blood pressure complained of acute vision loss. Dilated fundus examination evidenced a bilateral serous retinal detachment with macular involvement. The patient was unresponsive to oral antihypertensive therapy and dialysis treatment. The serous retinal detachment progressively decreased after the restoration of dialysis and antihypertensive therapy. The final visual acuity was 0.50 in both eyes. Discussion In cases of serous macular detachment, it is mandatory to rule out different systemic and ocular diseases. The presence of uncontrolled high blood pressure may produce aggressive bilateral retinal changes, thus hypertension must be under early and strict control in order to improve the visual outcomes. PMID:25120474

Phosphorus mass balance in a highly eutrophic semi-enclosed inlet near a big metropolis: a small inlet can contribute towards particulate organic matter production.

Science.gov (United States)

Asaoka, Satoshi; Yamamoto, Tamiji

2011-01-01

Terrigenous loading into enclosed water bodies has been blamed for eutrophic conditions marked by massive algal growth and subsequent hypoxia due to decomposition of dead algal cells. This study aims to describe the eutrophication and hypoxia processes in a semi-enclosed water body lying near a big metropolis. Phosphorus mass balance in a small inlet, Ohko Inlet, located at the head of Hiroshima Bay, Japan, was quantified using a numerical model. Dissolved inorganic phosphorous inflow from Kaita Bay next to the inlet was five times higher than that from terrigenous load, which may cause an enhancement of primary production. Therefore, it was concluded that not only the reduction of material load from the land and the suppression of benthic flux are needed, but also reducing the inflow of high phosphorus and oxygen depleted water from Kaita Bay will form a collective alternative measure to remediate the environmental condition of the inlet. Copyright © 2011 Elsevier Ltd. All rights reserved.

Blade bowing effects on radial equilibrium of inlet flow in axial compressor cascades

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Han XU

2017-10-01

Full Text Available The circumferentially averaged equation of the inlet flow radial equilibrium in axial compressor was deduced. It indicates that the blade inlet radial pressure gradient is closely related to the radial component of the circumferential fluctuation (CF source item. Several simplified cascades with/without aerodynamic loading were numerically studied to investigate the effects of blade bowing on the inlet flow radial equilibrium. A data reduction program was conducted to obtain the CF source from three-dimensional (3D simulation results. Flow parameters at the passage inlet were focused on and each term in the radial equilibrium equation was discussed quantitatively. Results indicate that the inviscid blade force is the inducement of the inlet CF due to geometrical asymmetry. Blade bowing induces variation of the inlet CF, thus changes the radial pressure gradient and leads to flow migration before leading edge (LE in the cascades. Positive bowing drives the inlet flow to migrate from end walls to mid-span and negative bowing turns it to the reverse direction to build a new equilibrium. In addition, comparative studies indicate that the inlet Mach number and blade loading can efficiently impact the effectiveness of blade bowing on radial equilibrium in compressor design.

Endovascular therapy of arteriovenous fistulae with electrolytically detachable coils

Energy Technology Data Exchange (ETDEWEB)

Jansen, O.; Doerfler, A.; Forsting, M.; Hartmann, M.; Kummer, R. von; Tronnier, V.; Sartor, K. [Dept. of Neuroradiology, University of Heidelberg Medical School (Germany)

1999-12-01

We report our experience in using Guglielmi electrolytically detachable coils (GDC) alone or in combination with other materials in the treatment of intracranial or cervical high-flow fistulae. We treated 14 patients with arteriovenous fistulae on brain-supplying vessels - three involving the external carotid or the vertebral artery, five the cavernous sinus and six the dural sinuses - by endovascular occlusion using electrolytically detachable platinum coils. The fistula was caused by trauma in six cases. In one case Ehlers-Danlos syndrome was the underlying disease, and in the remaining seven cases no aetiology could be found. Fistulae of the external carotid and vertebral arteries and caroticocavernous fistulae were reached via the transarterial route, while in all dural fistulae a combined transarterial-transvenous approach was chosen. All fistulae were treated using electrolytically detachable coils. While small fistulae could be occluded with electrolytically detachable coils alone, large fistulae were treated by using coils to build a stable basket for other types of coil or balloons. In 11 of the 14 patients, endovascular treatment resulted in complete occlusion of the fistula; in the remaining three occlusion was subtotal. Symptoms and signs were completely abolished by this treatment in 12 patients and reduced in 2. On clinical and neuroradiological follow-up (mean 16 months) no reappearance of symptoms was recorded. (orig.)

Jet Engine Fan Response to Inlet Distortions Generated by Ingesting Boundary Layer Flow

Science.gov (United States)

Giuliani, James Edward

Future civil transport designs may incorporate engines integrated into the body of the aircraft to take advantage of efficiency increases due to weight and drag reduction. Additional increases in engine efficiency are predicted if the inlets ingest the lower momentum boundary layer flow that develops along the surface of the aircraft. Previous studies have shown, however, that the efficiency benefits of Boundary Layer Ingesting (BLI) inlets are very sensitive to the magnitude of fan and duct losses, and blade structural response to the non-uniform flow field that results from a BLI inlet has not been studied in-depth. This project represents an effort to extend the modeling capabilities of TURBO, an existing rotating turbomachinery unsteady analysis code, to include the ability to solve the external and internal flow fields of a BLI inlet. The TURBO code has been a successful tool in evaluating fan response to flow distortions for traditional engine/inlet integrations. Extending TURBO to simulate the external and inlet flow field upstream of the fan will allow accurate pressure distortions that result from BLI inlet configurations to be computed and used to analyze fan aerodynamics and structural response. To validate the modifications for the BLI inlet flow field, an experimental NASA project to study flush-mounted S-duct inlets with large amounts of boundary layer ingestion was modeled. Results for the flow upstream and in the inlet are presented and compared to experimental data for several high Reynolds number flows to validate the modifications to the solver. Once the inlet modifications were validated, a hypothetical compressor fan was connected to the inlet, matching the inlet operating conditions so that the effect on the distortion could be evaluated. Although the total pressure distortion upstream of the fan was symmetrical for this geometry, the pressure rise generated by the fan blades was not, because of the velocity non-uniformity of the distortion

The efficacy of fluid-gas exchange for the treatment of postvitrectomy retinal detachment.

Science.gov (United States)

Jang, Ji Hye; Kim, Yu Cheol; Kim, Kwang Soo

2009-12-01

This study was designed to evaluate the efficacy of fluid-gas exchange for the treatment of postvitrectomy retinal detachment. We retrospectively reviewed the records of 33 consecutive patients (35 eyes) who underwent fluid-gas exchange treatment for postvitrectomy retinal detachment using the two-needle pars plana approach technique. The retinal reattachment rate was 80.0% after complete intravitreal gas disappearance following the fluid-gas exchange; the overall success rate was 65.7%. Visual acuity was improved or stable in 80.0% of cases; a two-line or greater vision improvement or a best-corrected visual acuity of 0.4 or better occurred in 62.9% of cases. The success rates for superior retinal detachments and posterior pole retinal detachments were 76.5% and 85.7%, respectively. Fluid-gas exchange represents a simple and cost-effective alternative outpatient procedure for retinal reattachment without reoperation for the treatment of superior and posterior pole retinal detachments.

The influence of refractive error and lattice degeneration on the incidence of retinal detachment.

Science.gov (United States)

Burton, T C

1989-01-01

This study indicates the feasibility of stratifying the general population into various risk pools for retinal detachment depending on a person's age, refractive status, and the presence of lattice degeneration. At first impression the risks seem at variance with the fine clinical studies of Byer, who has shown a very low detachment rate in the population with lattice degeneration. In all likelihood the vast majority of his patients were emmetropic or mildly myopic, so that very few would be expected to develop detachments during their entire lifetimes, let along during intervals of only 10 to 20 years. This study shows the futility of following, or treating prophylactically, young emmetropic individuals with lattice degeneration. Assuming that prophylaxis is actually effective, one would have to treat 1000 emmetropic lattice patients in the 30 to 39 year age group to prevent a single detachment over a 10-year period. Lattice patients with low to moderate degrees of myopia tend to develop detachments between 40 and 60 years of age caused by premature posterior vitreous separation and tractional tears. Clearly prophylaxis for this group is not warranted, since only 5% to 10% of these individuals will experience detachments in their lifetimes. On the other hand this study has verified the previous suspicions that persons with myopia exceeding -5.0 D accompanied by lattice degeneration have an extraordinarily high risk of detachment during their lifetimes. Detachments in this group tend to cluster in the second, third, and fourth decades, are typically caused by atrophic holes, are slowly progressive, and are often simultaneously bilateral. Enhanced vigilance is certainly appropriate during this time and perhaps consideration should be given to prophylactically treating this group. This would be no small task, since within a population of 1 million persons there would be about 1150 aged 10 to 39 years with myopia exceeding -5.0 D and lattice degeneration. Only 4

Vitrectomy, lensectomy and silicone oil tamponade in the management of retinal detachment associated with choroidal detachment

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Jian-Di Liu

2013-06-01

Full Text Available AIM: To report the results of combined vitrectomy, lensectomy and silicone oil (SO tamponade in treating primary rhegmatogenous retinal detachment (RRD associated with choroidal detachment (CD.METHODS: A retrospective, consecutive and case series study of 21 subjects with concurrent RRD associated with CD was conducted. All subjects underwent a standard three-port 20G pars plana vitrectomy (PPV with lensectomy and silicone oil tamponade. Mean follow-up time was 8 months (rang from 4 to 19 months. The primary and final anatomic success rate, visual acuity and final intraocular pressure(IOP were recorded and analyzed.RESULTS: Of 21 subjects, 8 were women and 13 were men. Age at presentation ranged from 22 to 75 years (mean 57.4 years. The presenting vision ranged from light perception to 0.15. The initial IOP ranged from 3mmHg to 12mmHg (mean 6.2mmHg. All eyes were phakic except one pseudophakic. No intraocular lens was implanted during the primary surgical intervention. Fifteen of 21 (71.4% eyes had retina reattached after one operation. Six eyes had recurrent inferior retinal detachment due to proliferation. Five of them were successfully reattached after one or more additional operations. Mean IOP at final follow-up was 15.2mmHg (range from 8mmHg to 20mmHg. One case declined for further operation. The final reattachment rate was 95.2%. Visual acuity improved in 19 (90.5% eyes, was unchanged in 1 (4.8% eye and decreased in 1 (4.8% eye.CONCLUSION: Combination of vitrectomy, lensectomy and silicone tamponade is an effective method in treating RRD associated with CD, reducing the incidence of postoperative hypotony.

Complex descemet′s membrane tears and detachment during phacoemulsification

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Faik Orucoglu

2015-01-01

Full Text Available Purpose: To report a case of complex Descemet′s membrane detachment (DMD and tears during phacoemulsification cataract surgery. Case Report: A 64-year-old woman underwent phacoemulsification surgery in her right eye and developed tears and partial loss of Descemet′s membrane (DM while the aspiration port was inserted through the main incision. Massive corneal edema obscured the view and the anterior chamber was barely visible the following day. Scheimpflug imaging was used to complement slit lamp examination in the postoperative period. Frequent topical corticosteroid drops were initiated. After 5 days of treatment, multiple tears and detachment of DM were visible and the anterior chamber was filled with air. After 5 weeks, the cornea regained much of its clarity despite large DM tears and focal loss of DM. Conclusion: Despite partial loss of DM, the corneal edema mostly disappeared after 5 weeks of air bubble injection. Scheimpflug imaging was beneficial in the diagnosis and monitoring of DM tears and detachments.

Screening for anthracnose disease resistance in strawberry using a detached leaf assay

Science.gov (United States)

Inoculation of detached strawberry leaves with Colletotrichum species may provide a rapid, non-destructive method of identifying anthracnose resistant germplasm. The reliability and validity of assessing disease severity is critical to disease management decisions. We inoculated detached strawberr...

Retinal detachment repair and cataract surgery in patients with atopic dermatitis.

Science.gov (United States)

Gnana Jothi, V; McGimpsey, S; Sharkey, J A; Chan, W C

2017-09-01

PurposeThe aim of this study is to report a case series of ocular complications including retinal detachment (RD) and cataract in atopic dermatitis (AD) and surgical management involving a majority of Caucasian patients.Patients and methodsThis study is an observational case series, originally designed as an audit. It involves detailed discussion of history, clinical features, and surgical management of patients presenting with retinal detachment and cataracts secondary to severe AD. Six consecutive patients with diagnosis of severe AD requiring posterior segment and cataract surgery were included in the study.ResultsEight eyes of six patients had retinal detachment. Most of them involved the temporal retina. The retinal breaks were located anteriorly close to the ora serrata in six eyes and Giant tear retinal (GRT) detachment was found in two eyes. Five eyes had proliferative vitreo-retinopathy (PVR) at presentation. All six patients had bilateral cataracts and cataract surgery was performed in eleven eyes. Bilateral simultaneous surgery was essential in two patients. Three eyes had secondary intra-ocular lens (IOL) implantation with pars plana vitrectomy for subluxed lens implant.ConclusionsAnterior retinal breaks and temporal RD are common in retinal detachment secondary to AD. PVR is often present, which makes surgical management difficult. Cataract formation is quite often and late subluxation of IOL may occur.

Effects of low-Z and high-Z impurities on divertor detachment and plasma confinement

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H.Q. Wang

2017-08-01

Full Text Available The impurity-seeded detached divertor is essential for heat exhaust in ITER and other reactor-relevant devices. Dedicated experiments with injection of N2, Ne and Ar have been performed in DIII-D to assess the impact of the different impurities on divertor detachment and confinement. Seeding with N2, Ne and Ar all promote divertor detachment, greatly reducing heat flux near the strike point. The upstream plasma density at the onset of detachment decreases with increasing impurity-puffing flow rates. For all injected impurity species, the confinement and pedestal pressure are correlated with the impurity content and the ratio of separatrix loss power to the l-H transition threshold power. As the divertor plasma approaches detachment, the high-Z impurity seeding tends to degrade the core confinement owing to the increased core radiation. In particular, Ar injection with up to 50% of the injected power radiating in the core cools the pedestal and core plasmas, thus significantly degrading the confinement. As for Ne seeding, medium confinement with H98∼0.8 can be maintained during the detachment phase with the pedestal temperature being reduced by about 50%. In contrast, in the N2 seeded plasmas, radiation is predominately confined in the boundary plasma, which leads to less effect on the confinement and pedestal. In the case of strong N2 gas puffing, the confinement recovers during the detachment, from ∼20% reduction at the onset of the detachment to greater than unity comparable to that before the seeding. The core and pedestal temperatures feature a reduction of 30% from the initial attached phase and remain nearly constant during the detachment phase. The improvement in confinement appears to arise from the increase in pedestal and core density despite the temperature reduction.

Simulation of experimentally achieved detached plasmas using the UEDGE code

International Nuclear Information System (INIS)

Porter, G.D.; Allen, S.; Fenstermacher, M.

1995-01-01

The introduction of a divertor Thomson scattering system in DIII-D has enabled accurate determination of the plasma properties in the divertor region. We identify two plasma regimes; detached and attached. The electron temperature in the detached regime is about 2 eV, much lower than 5 to 10 eV determined earlier. We show that fluid models of the DIII-D scrape-off layer plasma are able to reproduce many of the features of these two plasma regimes, including the boundaries for transition between them. Detailed comparison between the results obtained from the fluid models and experiment suggest the models underestimate the spatial extent of the low temperature region associated the detached plasma mode. We suggest that atomic physics processes at the low electron temperatures reported here may account for this discrepancy

Unsteady flow characteristic analysis of turbine based combined cycle (TBCC inlet mode transition

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Jun Liu

2015-09-01

Full Text Available A turbine based combined cycle (TBCC propulsion system uses a turbine-based engine to accelerate the vehicle from takeoff to the mode transition flight condition, at which point, the propulsion system performs a “mode transition” from the turbine to ramjet engine. Smooth inlet mode transition is accomplished when flow is diverted from one flowpath to the other, without experiencing unstart or buzz. The smooth inlet mode transition is a complex unsteady process and it is one of the enabling technologies for combined cycle engine to become a functional reality. In order to unveil the unsteady process of inlet mode transition, the research of over/under TBCC inlet mode transition was conducted through a numerical simulation. It shows that during the mode transition the terminal shock oscillates in the inlet. During the process of inlet mode transition mass flow rate and Mach number of turbojet flowpath reduce with oscillation. While in ramjet flowpath the flow field is non-uniform at the beginning of inlet mode transition. The speed of mode transition and the operation states of the turbojet and ramjet engines will affect the motion of terminal shock. The result obtained in present paper can help us realize the unsteady flow characteristic during the mode transition and provide some suggestions for TBCC inlet mode transition based on the smooth transition of thrust.

Validation of Helium Inlet Design for ITER Toroidal Field Coil

CERN Document Server

Boyer, C; Hamada, K; Foussat, A; Le Rest, M; Mitchell, N; Decool, P; Savary, F; Sgobba, S; Weiss, K-P

2014-01-01

The ITER organization has performed design and its validation tests on a helium inlet structure for the ITER Toroidal Field (TF) coil under collaboration with CERN, KIT, and CEA-Cadarache. Detailed structural analysis was performed in order to optimize the weld shape. A fatigue resistant design on the fillet weld between the shell covers and the jacket is an important point on the helium inlet structure. A weld filler material was selected based on tensile test at liquid helium temperature after Nb$_{3}$Sn reaction heat treatment. To validate the design of the weld joint, fatigue tests at 7 K were performed using heat-treated butt weld samples. A pressure drop measurement of a helium inlet mock-up was performed by using nitrogen gas at room temperature in order to confirm uniform flow distribution and pressure drop characteristic. These tests have validated the helium inlet design. Based on the validation, Japanese and European Union domestic agencies, which have responsibilities of the TF coil procurement, a...

Inlet effect induced ''upstream'' critical heat flux in smooth tubes

International Nuclear Information System (INIS)

Kitto, J.B. Jr.

1986-01-01

An unusual form of ''upstream'' critical heat flux (CHF) has been observed and directly linked to the inlet flow pattern during an experimental study of high pressure (17 - 20 MPa) water flowing through a vertical 38.1 mm ID smooth bore tube with uniform axial and nonuniform circumferential heating. These upstream CHF data were characterized by temperature excursions which initially occurred at a relatively fixed axial location in the middle of the test section while the outlet and inlet heated lengths experienced no change. A rifled tube inlet flow conditioner could be substituted for a smooth tube section to generate the desired swirling inlet flow pattern. The upstream CHF data were found to match data from a uniformly heated smooth bore tube when the comparison was made using the peak local heat flux. The mechanism proposed to account for the upstream CHF observations involves the destructive interference between the decaying swirl flow and the secondary circumferential liquid flow field resulting from the one-sided heating

Lowest auto-detachment state of the water anion

International Nuclear Information System (INIS)

Houfek, K.; Cizek, M.

2016-01-01

Because of the abundance of water in living tissue the reactive low-energy electron collisions with the water molecule represent an important step in the radiation damage of cells. In this paper, the potential energy surface of the ground state of the water anion H_2O"- is carefully mapped using multireference configuration interaction (MRCI) calculations for a large range of molecular geometries. Particular attention is paid to a consistent description of both the O"-+H_2 and OH"-+H asymptotes and to a relative position of the anion energy to the ground state energy of the neutral molecule. The auto-detachment region, where the anion state crosses to the electronic continuum is identified. The local minimum in the direction of the O"- + H_2 channel previously reported by Werner et al. [J. Chem. Phys. 87, 2913 (1987)] is found to be slightly off the linear geometry and is separated by a saddle from the auto-detachment region. The auto-detachment region is directly accessible from the OH"-+H asymptote. For the molecular geometries in the auto-detachment region and in its vicinity we also performed fixed-nuclei electron-molecule scattering calculations using the R-matrix method. Tuning of consistency of a description of the correlation energy in both the multireference CI and R-matrix calculations is discussed. Two models of the correlation energy within the R-matrix method that are consistent with the quantum chemistry calculations are found. Both models yield scattering quantities in a close agreement. The results of this work will allow a consistent formulation of the nonlocal resonance model of the water anion in a future publication

Assessment of X-point target divertor configuration for power handling and detachment front control

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M.V. Umansky

2017-08-01

Full Text Available A study of long-legged tokamak divertor configurations is performed with the edge transport code UEDGE (Rognlien et al., J. Nucl. Mater. 196, 347, 1992. The model parameters are based on the ADX tokamak concept design (LaBombard et al., Nucl. Fusion 55, 053020, 2015. Several long-legged divertor configurations are considered, in particular the X-point target configuration proposed for ADX, and compared with a standard divertor. For otherwise identical conditions, a scan of the input power from the core plasma is performed. It is found that as the power is reduced to a threshold value, the plasma in the outer leg transitions to a fully detached state which defines the upper limit on the power for detached divertor operation. Reducing the power further results in the detachment front shifting upstream but remaining stable. At low power the detachment front eventually moves to the primary X-point, which is usually associated with degradation of the core plasma, and this defines the lower limit on the power for the detached divertor operation. For the studied parameters, the operation window for a detached divertor in the standard divertor configuration is very small, or even non-existent; under the same conditions for long-legged divertors the detached operation window is quite large, in particular for the X-point target configuration, allowing a factor of 5–10 variation in the input power. These modeling results point to possibility of stable fully detached divertor operation for a tokamak with extended divertor legs.

Critical flashing flows in nozzles with subcooled inlet conditions

International Nuclear Information System (INIS)

Abuaf, N.; Jones, O.C. Jr.; Wu, B.J.C.

1983-01-01

Examination of a large number of experiments dealing with flashing flows in converging and converging-diverging nozzles reveals that knowledge of the flashing inception point is the key to the prediction of critical flow rates. An extension of the static flashing inception correlation of Jones [16] and Alamgir and Lienhard [17] to flowing systems has allowed the determination of the location of flashing inception in nozzle flows with subcooled inlet conditions. It is shown that in all the experiments examined with subcooled inlet regardless of the degree of inlet subcooling, flashing inception invariably occurred very close to the throat. A correlation is given to predict flashing inception in both pipes and nozzles which matches all data available, but is lacking verification in intermediate nozzle geometries where turbulence may be important. A consequence of this behavior is that the critical mass flux may be correlated to the pressure difference between the nozzle inlet and flashing inception, through a single phase liquid discharge coefficient and an accurate prediction of the flashing inception pressure at the throat. Comparison with the available experiments indicate that the predicted mass fluxes are within 5 percent of the measurements

Visual recovery after surgical repair of chronic macular detachment associated with peripheral retinoschisis

OpenAIRE

Vaidehi S. Dedania; Devon H. Ghodasra; Mark W. Johnson

2018-01-01

Purpose: To report 2 cases of chronic macular detachment associated with peripheral retinoschisis in which surgical repair resulted in significant visual recovery. Observations: A 44-year-old man and 60-year-old woman were evaluated for chronic macular detachment, with a duration of 5 years and 6 months, respectively. In each case, optical coherence tomography was used to establish a diagnosis of full-thickness macular detachment resulting from peripheral retinoschisis and to confirm or ident...

Magnetic Detachment and Plume Control in Escaping Magnetized Plasma

International Nuclear Information System (INIS)

Schmit, P.F.; Fisch, N.J.

2008-01-01

The model of two-fluid, axisymmetric, ambipolar magnetized plasma detachment from thruster guide fields is extended to include plasmas with non-zero injection angular velocity profiles. Certain plasma injection angular velocity profiles are shown to narrow the plasma plume, thereby increasing exhaust efficiency. As an example, we consider a magnetic guide field arising from a simple current ring and demonstrate plasma injection schemes that more than double the fraction of useful exhaust aperture area, more than halve the exhaust plume angle, and enhance magnetized plasma detachment

Classifier utility modeling and analysis of hypersonic inlet start/unstart considering training data costs

Science.gov (United States)

Chang, Juntao; Hu, Qinghua; Yu, Daren; Bao, Wen

2011-11-01

Start/unstart detection is one of the most important issues of hypersonic inlets and is also the foundation of protection control of scramjet. The inlet start/unstart detection can be attributed to a standard pattern classification problem, and the training sample costs have to be considered for the classifier modeling as the CFD numerical simulations and wind tunnel experiments of hypersonic inlets both cost time and money. To solve this problem, the CFD simulation of inlet is studied at first step, and the simulation results could provide the training data for pattern classification of hypersonic inlet start/unstart. Then the classifier modeling technology and maximum classifier utility theories are introduced to analyze the effect of training data cost on classifier utility. In conclusion, it is useful to introduce support vector machine algorithms to acquire the classifier model of hypersonic inlet start/unstart, and the minimum total cost of hypersonic inlet start/unstart classifier can be obtained by the maximum classifier utility theories.

A life-cycle model for wave-dominated tidal inlets along passive margin coasts of North America

Science.gov (United States)

Seminack, Christopher T.; McBride, Randolph A.

2018-03-01

A regional overview of 107 wave-dominated tidal inlets along the U.S. Atlantic coast, U.S. Gulf of Mexico coast, and Canadian Gulf of St. Lawrence coast yielded a generalized wave-dominated tidal inlet life-cycle model that recognized the rotational nature of tidal inlets. Tidal inlets are influenced by concurrently acting processes transpiring over two timescales: short-term, event-driven processes and long-term, evolutionary processes. Wave-dominated tidal inlets are classified into three rotational categories based on net longshore sediment transport direction and rotation direction along the landward (back-barrier) portion of the inlet channel: downdrift channel rotation, updrift channel rotation, or little-to-no channel rotation. Lateral shifting of the flood-tidal delta depocenter in response to available estuarine accommodation space appears to control inlet channel rotation. Flood-tidal delta deposits fill accommodation space locally within the estuary (i.e., creating bathymetric highs), causing the tidal-inlet channel to rotate. External influences, such as fluvial discharge, pre-existing back-barrier channels, and impeding salt marsh will also influence inlet-channel rotation. Storm events may rejuvenate the tidal inlet by scouring sediment within the flood-tidal delta, increasing local accommodation space. Wave-dominated tidal inlets are generally unstable and tend to open, concurrently migrate laterally and rotate, infill, and close. Channel rotation is a primary reason for wave-dominated tidal inlet closure. During rotation, the inlet channel lengthens and hydraulic efficiency decreases, thus causing tidal prism to decrease. Tidal prism, estuarine accommodation space, and sediment supply to the flood-tidal delta are the primary variables responsible for tidal inlet rotation. Stability of wave-dominated tidal inlets is further explained by: stability (S) = tidal prism (Ω) + estuarine accommodation space (V) - volume of annual sediment supply (Mt

Seasonal behaviour of tidal inlets in a tropical monsoon area

NARCIS (Netherlands)

Lam, N.T.; Stive, M.J.F.; Verhagen, H.J.; Wang, Z.B.

2008-01-01

Morphodynamics of a tidal inlet system on a micro-tidal coast in a tropical monsoon influenced region is modelled and discussed. Influences of river flow and wave climate on the inlet morphology are investigated with the aid of process-based state-of-the-art numerical models. Seasonal and episodic

Electron detachment in ion-atom collisions

International Nuclear Information System (INIS)

Vreugd, C. de.

1980-01-01

The electron detachment process that occurs in negative ion-atom collisions is investigated. Differential cross sections were measured for the collisions of F - , Cl - , Br - , I - on He, Ne, Ar, Kr, Xe, Na and K. Electron energy distributions were obtained for some of the systems. (Auth.)

Adenocarcinoma of the lung presenting as retinal detachment

Directory of Open Access Journals (Sweden)

Kaushik Saha

2014-01-01

Full Text Available Retinal detachment is a rare presentation of lung cancer. A young female presented with blurring of vision in her right eye for the last 10 days without any history of trauma. On indirect ophthalmoscopy, there was a presence of right sided retinal detachment which was treated with oral prednisolone (60 mg/day. After 1 month of continuous treatment, she came back with dry cough left sided chest pain and deterioration of her eye symptoms. Chest X-ray showed left lung mass. Computed tomography guided fine needle aspiration cytology and with immunohistochemistry confirmed adenocarcinoma of the lung. She was treated with 6 cycles of chemotherapy with paclitaxel and gemcitabine.

Impact of inlet coherent motions on compressor performance

Science.gov (United States)

Forlese, Jacopo; Spoleti, Giovanni

2017-08-01

Automotive engine induction systems may be characterized by significant flow angularity and total pressure distortion at the compressor inlet. The impact of the swirl on compressor performance should be quantified to guide the design of the induction systems. In diesel engines, the presence of a valve for flow reduction and control of low pressure EGR recirculation could generate coherent motion and influence the performance of the compressor. Starting from experimental map, the compressor speed-lines have been simulated using a 3D CFD commercial code imposing different concept motion at the inlet. The swirl intensity, the direction and the number of vortices have been imposed in order to taking into account some combinations. Finally, a merit function has been defined to evaluate the performance of the compressor with the defined swirl concepts. The aim of the current work is to obtain an indication on the effect of a swirling motion at the compressor inlet on the engine performance and provide a guideline to the induction system design.

Safety detaching hook specification.

CSIR Research Space (South Africa)

Roux, JD

1999-05-01

Full Text Available hydraulic tensioning system The impactor must subject the safety detaching hook to an impact energy of 150 kJ minimum. A high speed digital imaging system, capable of recording at least 2000 full frames per second, shall be used to record video images... document compiled by the Contractor, detailing all major events in the production phase, including but not necessarily limited to inspection requirements, test procedures and acceptance/rejection criteria, sampling plans and equipment to be employed...

Euler Calculations at Off-Design Conditions for an Inlet of Inward Turning RBCC-SSTO Vehicle

Science.gov (United States)

Takashima, N.; Kothari, A. P.

1998-01-01

The inviscid performance of an inward turning inlet design is calculated computationally for the first time. Hypersonic vehicle designs based on the inward turning inlets have been shown analytically to have increased effective specific impulse and lower heat load than comparably designed vehicles with two-dimensional inlets. The inward turning inlets are designed inversely from inviscid stream surfaces of known flow fields. The computational study is performed on a Mach 12 inlet design to validate the performance predicted by the design code (HAVDAC) and calculate its off-design Mach number performance. The three-dimensional Euler equations are solved for Mach 4, 8, and 12 using a software package called SAM, which consists of an unstructured mesh generator (SAMmesh), a three-dimensional unstructured mesh flow solver (SAMcfd), and a CAD-based software (SAMcad). The computed momentum averaged inlet throat pressure is within 6% of the design inlet throat pressure. The mass-flux at the inlet throat is also within 7 % of the value predicted by the design code thereby validating the accuracy of the design code. The off-design Mach number results show that flow spillage is minimal, and the variation in the mass capture ratio with Mach number is comparable to an ideal 2-D inlet. The results from the inviscid flow calculations of a Mach 12 inward turning inlet indicate that the inlet design has very good on and off-design performance which makes it a promising design candidate for future air-breathing hypersonic vehicles.

Coastal Response, a system of detached breakwaters

Science.gov (United States)

García Ortiz, Isabelo; Negro Valdecantos, Vicente; Santos López, Jose; Esteban, María Dolores

2017-04-01

The coastline's sedimentary response in the form of a tombolo or semi-tombolo (salient) as a result of the construction of detached breakwaters is an aspect that should be known in the design phase so that these marine structures may be properly designed. In achieving an ecological, social and economic value, such areas must also be properly managed. All design methods in existence since Dean (1978) are mainly based on hypotheses formulated from geometric studies on existing formations. No relationship at all is established with climate and littoral dynamics typical of the location (only Suh and Darlymple (1987) and the Japanese Ministry of Construction (1986) present relationships depending on wave variables). Neither has the influence on systems with more than two breakwaters been studied. These methods are not fully adapted to the cases existing on the Spanish Mediterranean littoral. The lines of investigation as proposed by L. Bricio and V. Negro (2010) were continued with for this study. These researchers developed a method for dimensioning isolated, detached breakwaters and their semi-tombolo or tombolo associated formations using all the characteristics of the site (energy, geometric and structural), specific climate and geomorphology and littoral dynamics' characteristics. This methodology is currently acknowledged and accepted in works undertaken on the Spanish Mediterranean littoral. A linear regression was obtained in the investigation undertaken on the 18 detached breakwater systems along the whole of the 1670 km of the Spanish Mediterranean littoral using the proposals made by L. Bricio and V. Negro. The adjustment of R2 ≥ 0.90 was used for the sandy, tombolo formations behind all the detached breakwater systems between several non-dimensional monomials displaying the most representative characteristics of the site. L/H12 + (2ṡB)/G =12,15ṡ(X/Xc)+7,3231 X: Distance of breakwaters from coastline Xc: Distance from coastline where the closure depth

Single- and double-electron detachment in collisions of two negative hydrogen ions

International Nuclear Information System (INIS)

Melchert, F.; Schulze, R.; Kruedener, S.; Meuser, S.; Salzborn, E.

1995-01-01

Employing the crossed-beams technique in conjunction with a beam-pulsing method, we have measured absolute cross sections σ tot for the process H - + H - → H O +... for CM energies between 2.5 and 100 keV. Combining the present results with our previously measured cross sections for double-electron detachment (σ OO ) and triple-electron detachment (σ 0+ ), we obtain cross sections σ 0- for the single electron detachment process from the relation σ 0- = σ tot -σ 00 -σ 0+ . The experimental data of single- and double-electron detachment are well described by theoretical results based on the non-stationary tunnelling approach. Both cross sections are calculated for CM energies between 0.15 and 300 keV. A new two-electron simultaneous transition mechanism is introduced. The importance of this process for the theoretical assessment of the experimental results is discussed. (Author)

Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment

Directory of Open Access Journals (Sweden)

Takao Morinaga

2018-06-01

Full Text Available Cholesterol, a major component of the plasma membrane, determines the physicalproperties of biological membranes and plays a critical role in the assembly of membranemicrodomains. Enrichment or deprivation of membrane cholesterol affects the activities of manysignaling molecules at the plasma membrane. Cell detachment changes the structure of the plasmamembrane and influences the localizations of lipids, including cholesterol. Recent studies showedthat cell detachment changes the activities of a variety of signaling molecules. We previously reportedthat the localization and the function of the Src-family kinase Lyn are critically regulated by itsmembrane anchorage through lipid modifications. More recently, we found that the localization andthe activity of Lyn were changed upon cell detachment, although the manners of which vary betweencell types. In this review, we highlight the changes in the localization of Lyn and a role of cholesterolin the regulation of Lyn’s activation following cell detachment.

General Investigation of Tidal Inlets: Stability of Selected United States Tidal Inlets

Science.gov (United States)

1991-09-01

characteristics in relation to the variability of the hydr; aulic parameters. An inlet can fall into any of four "stability" classes 48 Orientation Parameter 80...nlot he ~ :Ke(: t 93. If a fairly straight coast with uniform offshore slopes and a regionally homogeneous wave climate is considered, a reasonable...expectation is LhaL the longshore transport quantities and directions are homogeneous. Given a long-term variability in wave climate , a corresponding

30 CFR 77.303 - Hot gas inlet chamber dropout doors.

Science.gov (United States)

2010-07-01

... Section 77.303 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND... employ a hot gas inlet chamber shall be equipped with drop-out doors at the bottom of the inlet chamber...

Retinal detachment secondary to ocular perforation during retrobulbar Anaesthesia

Directory of Open Access Journals (Sweden)

Gopal Lingam

1995-01-01

Full Text Available The clinical characteristics and the retinal breaks associated with rhegmatogenous retinal detachments secondary to accidental globe perforation during local infiltration anaesthesia in five highly myopic eyes are presented. Retinal detachment was total with variable proliferative vitreoretinopathy. The pattern of retinal breaks was rather typical and predictable. Management involved vitreous surgery with internal tamponade by silicone oil in four eyes and perfluoropropane gas in one eye. At the last follow-up, all eyes had attached retina. One eye did not recover useful vision due to possible concurrent optic nerve damage.

Retinal detachment in black South Africans

African Journals Online (AJOL)

low incidence of retinal detachment in black patients is not known. ... a retinal break. Predisposing factors include peripheral retinal degenerations, myopia, aphakia and trauma. Delay in presentation increases the difficulty in achieving adequate surgical ... On examination, note was taken of the visual acuity in both eyes, the ...

Detached Eddy Simulations of Hypersonic Transition

Science.gov (United States)

Yoon, S.; Barnhardt, M.; Candler, G.

2010-01-01

This slide presentation reviews the use of Detached Eddy Simulation (DES) of hypersonic transistion. The objective of the study was to investigate the feasibility of using CFD in general, DES in particular, for prediction of roughness-induced boundary layer transition to turbulence and the resulting increase in heat transfer.

Selective catalytic reduction converter design: The effect of ammonia nonuniformity at inlet

International Nuclear Information System (INIS)

Paramadayalan, Thiyagarajan; Pant, Atul

2013-01-01

A three-dimensional CFD model of SCR converter with detailed chemistry is developed. The model is used to study the effects of radial variation in inlet ammonia profile on SCR emission performance at different temperatures. The model shows that radial variation in inlet ammonia concentration affects the SCR performance in the operating range of 200-400 .deg. C. In automotive SCR systems, ammonia is non-uniformly distributed due to evaporation/reaction of injected urea, and using a 1D model or a 3D model with flat ammonia profile at inlet for these conditions can result in erroneous emission prediction. The 3D SCR model is also used to study the effect of converter design parameters like inlet cone angle and monolith cell density on the SCR performance for a non-uniform ammonia concentration profile at the inlet. The performance of SCR is evaluated using DeNO x efficiency and ammonia slip

An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment

OpenAIRE

Mathew, David J.; Sarma, Saurabh Kumar; Basaiawmoit, Jennifer V.

2016-01-01

Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment. An asymptomatic 35-year-old lady with minimal refractive error was found to have extensive lattice degeneration, peripheral retinal detachment and fibrotic changes peripherally with elevation of retinal vessels on dilated retinal examination. There were al...

CFD analysis of flow distribution at the core inlet of SMART

Energy Technology Data Exchange (ETDEWEB)

Bae, Youngmin, E-mail: ybae@kaeri.re.kr [Korea Atomic Energy Research Institute, 150 Deokjin-dong, Yuseong-gu, Daejeon 305-353 (Korea, Republic of); Kim, Young In; Park, Cheon Tae [Korea Atomic Energy Research Institute, 150 Deokjin-dong, Yuseong-gu, Daejeon 305-353 (Korea, Republic of)

2013-05-15

Highlights: ► Core inlet flow distribution of system-integrated modular advanced reactor (SMART) is numerically investigated. ► Effects of mesh resolution, turbulence model, Reynolds number, and inflow condition are examined. ► Numerical results show that lower core support plate effectively distributes the flow at the core inlet of SMART. -- Abstract: This study numerically investigates the flow distribution at the core inlet region of the system-integrated modular advanced reactor (SMART). The single-phase turbulent flow is computed by the commercial CFD code, Fluent 12.0 on the computational domain consisting of three main parts: fuel assemblies, a lower core support plate, and a flow skirt. Simulations are carried out with different mesh resolutions, turbulence models, and upstream boundary conditions. The CFD results show that the flow distribution at the core inlet is almost identical for the two Reynolds numbers and turbulence models tested here, and the effect of mesh refinement on the flow distribution at the core inlet is negligible. It is also found that under a uniform upstream boundary condition, the maximum difference in mass flow rate between the fuel assemblies is less than 2%, while it slightly increases to 2.3% under a non-uniform condition. These results consequently indicate that the present design of the lower core support plate effectively distributes the flow at the core inlet of SMART, even when the flow discharged from the upstream has a certain degree of non-uniformity.

Negative ion detachment cross sections

International Nuclear Information System (INIS)

Champion, R.L.; Doverspike, L.D.

1992-10-01

The authors have measured absolute cross sections for electron detachment and charge exchange for collision of O and S with atomic hydrogen, have investigated the sputtering and photodesorption of negative ions from gas covered surfaces, and have begun an investigation of photon-induced field emission of electrons from exotic structures. Brief descriptions of these activities as well as future plans for these projects are given below

Middle Miocene E-W tectonic horst structure of Crete through extensional detachment faults

International Nuclear Information System (INIS)

Papanikolaou, D; Vassilakis, E

2008-01-01

Two east-west trending extensional detachment faults have been recognized in Crete, one with top-to-the-north motion of the hanging wall toward the Cretan Sea and one with top-to-the-south motion of the hanging wall toward the Libyan Sea. The east-west trending zone between these two detachment faults, which forms their common footwall, comprises a tectonic horst formed during Middle Miocene slip on the detachment faults. The detachment faults disrupt the overall tectono-stratigraphic succession of Crete and are localized along pre-existing thrust faults and along particular portions of the stratigraphic sequence, including the transition between the Permo-Triassic Tyros Beds and the base of the Upper Triassic-Eocene carbonate platform of the Tripolis nappe. By recognizing several different tectono-stratigraphic formations within what is generally termed the 'phyllite-quartzite', it is possible to distinguish these extensional detachment faults from thrust faults and minor discontinuities in the sequence. The deformation history of units within Crete can be summarized as: (i) compressional deformation producing arc-parallel east-west trending south-directed thrust faults in Oligocene to Early Miocene time (ii) extensional deformation along arc-parallel, east-west trending detachment faults in Middle Miocene time, with hanging wall motion to the north and south; (iii) Late Miocene-Quaternary extensional deformation along high-angle normal and oblique normal faults that disrupt the older arc-parallel structures

Vortex Generators in a Two-Dimensional, External-Compression Supersonic Inlet

Science.gov (United States)

Baydar, Ezgihan; Lu, Frank K.; Slater, John W.

2016-01-01

Computational fluid dynamics simulations are performed as part of a process to design a vortex generator array for a two-dimensional inlet for Mach 1.6. The objective is to improve total pressure recovery a on at the engine face of the inlet. Both vane-type and ramp-type vortex generators are examined.

Parametric Data from a Wind Tunnel Test on a Rocket-Based Combined-Cycle Engine Inlet

Science.gov (United States)

Fernandez, Rene; Trefny, Charles J.; Thomas, Scott R.; Bulman, Mel J.

2001-01-01

A 40-percent scale model of the inlet to a rocket-based combined-cycle (RBCC) engine was tested in the NASA Glenn Research Center 1- by 1-Foot Supersonic Wind Tunnel (SWT). The full-scale RBCC engine is scheduled for test in the Hypersonic Tunnel Facility (HTF) at NASA Glenn's Plum Brook Station at Mach 5 and 6. This engine will incorporate the configuration of this inlet model which achieved the best performance during the present experiment. The inlet test was conducted at Mach numbers of 4.0, 5.0, 5.5, and 6.0. The fixed-geometry inlet consists of an 8 deg.. forebody compression plate, boundary layer diverter, and two compressive struts located within 2 parallel sidewalls. These struts extend through the inlet, dividing the flowpath into three channels. Test parameters investigated included strut geometry, boundary layer ingestion, and Reynolds number (Re). Inlet axial pressure distributions and cross-sectional Pitot-pressure surveys at the base of the struts were measured at varying back-pressures. Inlet performance and starting data are presented. The inlet chosen for the RBCC engine self-started at all Mach numbers from 4 to 6. Pitot-pressure contours showed large flow nonuniformity on the body-side of the inlet. The inlet provided adequate pressure recovery and flow quality for the RBCC cycle even with the flow separation.

Early rhegmatogenous retinal detachment following laser in situ keratomileusis for high myopia.

Science.gov (United States)

Farah, M E; Höfling-Lima, A L; Nascimento, E

2000-01-01

Four eyes had early rhegmatogenous retinal detachment within 3 months of laser in situ keratomileusis (LASIK) for correction of high myopia using the microkeratome, Clear Corneal Molder. In two eyes, retinal detachment resulted from horseshoe tears, one occurring in an otherwise normal region of the retina and the other at the margin of an area of lattice degeneration detected during preoperative examination. The first eye was treated with retinopexy using a 287 encircling scleral exoplant, drainage of subretinal fluid, and laser photocoagulation by indirect ophthalmoscopy. The other eye was treated with pneumatic retinopexy and cryotherapy. In the other eyes, retinal detachment was the result of giant tears with no evidence of prior retinal degeneration. These eyes were treated with pars plana vitrectomy, fluid-gas exchange with 15% perfluoropropane (C3F8), endolaser photocoagulation, and a 42 encircling scleral exoplant. After treatment, the first two eyes achieved spectacle-corrected visual acuity of 20/40. In the last two eyes, final spectacle-corrected visual acuity was 20/400 in one eye and light perception in the other. Although no cause-effect relationship between LASIK and retinal detachment can be stated, these cases suggest that LASIK may be associated with retinal detachment, particularly in highly myopic eyes. Further studies are necessary to determine high-risk patient characteristics.

Unwanted detachment of the Solitaire device during mechanical thrombectomy in acute ischemic stroke.

Science.gov (United States)

Castaño, C; Dorado, L; Remollo, S; García-Bermejo, P; Gomis, M; Pérez de la Ossa, N; Millán, M; García-Sort, M R; Hidalgo, C; López-Cancio, E; Cubells, C; Dávalos, A

2016-01-27

The use of retrievable stents for endovascular clot retrieval has dramatically improved successful revascularization and clinical outcome in selected patients with acute stroke. To describe the rate and clinical consequences of unwanted spontaneous detachment of these devices during mechanical thrombectomy. We studied 262 consecutive patients treated with the retrievable stent, Solitaire, for acute ischemic stroke between November 2008 and April 2015. Clinical, procedural, and outcome variables were compared between patients with and without unexpected detachment of this device. Detachment was classified as proximal to the stent proximal marker (type A) or distal to the marker (type B). Poor functional outcome was defined as modified Rankin scale score >2 at 90 days. Unwanted detachment occurred in 6/262 (2.3%) cases, four of type A and two of type B. Stent recovery was possible in three patients, all of 'type A', but in none of 'type B'. The number of prior passes was higher in patients with undesired detachment (3 (2-5) vs 2 (1-3), p=0.007). Detachment was associated with higher rate of symptomatic intracranial hemorrhage (SICH) (33.3% vs 4.3%, p=0.001), poorer outcome (100% vs 54.8%, p=0.028), and higher mortality rate at 90 days (50% vs 17%, p=0.038). Unwanted detachment of a Solitaire is an uncommon complication during mechanical thrombectomy in patients with acute ischemic stroke and is associated with the clot retrieval attempts, SICH, poor outcome, and higher mortality. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Design of a reactor inlet temperature controller for EBR-2 using state feedback

International Nuclear Information System (INIS)

Vilim, R.B.; Planchon, H.P.

1990-01-01

A new reactor inlet temperature controller for pool type liquid-metal reactors has been developed and will be tested in EBR-II. The controller makes use of modern control techniques to take into account stratification and mixing in the cold pool during normal operation. Secondary flowrate is varied so that the reactor inlet temperature tracks a setpoint while reactor outlet temperature, primary flowrate and secondary cold leg temperature are treated as exogenous disturbances and are free to vary. A disturbance rejection technique minimizes the effect of these disturbances on inlet temperature. A linear quadratic regulator improves inlet temperature response. Tests in EBR-II will provide experimental data for assessing the performance improvements that modern control can produce over the existing EBR-II analog inlet temperature controller. 10 refs., 8 figs

Model of detached plasmas

International Nuclear Information System (INIS)

Yoshikawa, S.; Chance, M.

1986-07-01

Recently a tokamak plasma was observed in TFTR that was not limited by a limiter or a divertor. A model is proposed to explain this equilibrium, which is called a detached plasma. The model consists of (1) the core plasma where ohmic heating power is lost by anomalous heat conduction and (2) the shell plasma where the heat from the core plasma is radiated away by the atomic processes of impurity ions. A simple scaling law is proposed to test the validity of this model

Phycocyanin stability in microcapsules processed by spray drying method using different inlet temperature

Science.gov (United States)

Purnamayati, L.; Dewi, EN; Kurniasih, R. A.

2018-02-01

Phycocyanin is natural blue colorant which easily damages by heat. The inlet temperature of spray dryer is an important parameter representing the feature of the microcapsules.The aim of this study was to investigate the phycocyanin stability of microcapsules made from Spirulina sp with maltodextrin and κ-Carrageenan as the coating material, processed by spray drying method in different inlet temperature. Microcapsules were processed in three various inlet temperaturei.e. 90°C, 110°C, and 130°C, respectively. The results indicated that phycocyanin microcapsule with 90°C of inlet temperature produced the highest moisture content, phycocyanin concentration and encapsulation efficiency of 3,5%, 1,729% and 29,623%, respectively. On the other hand, the highest encapsulation yield was produced by 130°C of theinlet temperature of 29,48% and not significantly different with 110°C. The results of Scanning Electron Microscopy (SEM) showed that phycocyanin microcapsules with 110°C of inlet temperature produced the most rounded shape. To sum up, 110°C was the best inlet temperature to phycocyanin microencapsulation by the spray dryer.

Proteomic analysis of the vitreous following experimental retinal detachment in rabbits

DEFF Research Database (Denmark)

Mandal, Nakul; Lewis, Geoffrey P.; Fisher, Steven K.

2015-01-01

of the vitreous following experimental retinal detachment using a comparative proteomic based approach. Materials and Methods. Retinal detachment was created in the right eyes of six New Zealand red pigmented rabbits. Sham surgery was undertaken in five other rabbits that were used as controls. After seven days......Purpose. The pathogenesis of rhegmatogenous retinal detachment (RRD) remains incompletely understood, with no clinically effective treatment for potentially severe complications such as photoreceptor cell death and proliferative vitreoretinopathy. Here we investigate the protein profile...... the eyes were enucleated and the vitreous was removed. The vitreous samples were evaluated with two-dimensional polyacrylamide gel electrophoresis and the differentially expressed proteins were identified with tandem mass spectrometry. Results. Ten protein spots were found to be at least twofold...

Effect of inlet cone pipe angle in catalytic converter

Science.gov (United States)

Amira Zainal, Nurul; Farhain Azmi, Ezzatul; Arifin Samad, Mohd

2018-03-01

The catalytic converter shows significant consequence to improve the performance of the vehicle start from it launched into production. Nowadays, the geometric design of the catalytic converter has become critical to avoid the behavior of backpressure in the exhaust system. The backpressure essentially reduced the performance of vehicles and increased the fuel consumption gradually. Consequently, this study aims to design various models of catalytic converter and optimize the volume of fluid flow inside the catalytic converter by changing the inlet cone pipe angles. Three different geometry angles of the inlet cone pipe of the catalytic converter were assessed. The model is simulated in Solidworks software to determine the optimum geometric design of the catalytic converter. The result showed that by decreasing the divergence angle of inlet cone pipe will upsurge the performance of the catalytic converter.

Coupled Analysis of an Inlet and Fan for a Quiet Supersonic Jet

Science.gov (United States)

Chima, Rodrick V.; Conners, Timothy R.; Wayman, Thomas R.

2010-01-01

A computational analysis of a Gulfstream isentropic external compression supersonic inlet coupled to a Rolls-Royce fan has been completed. The inlet was designed for a small, low sonic boom supersonic vehicle with a design cruise condition of M = 1.6 at 45,000 ft. The inlet design included an annular bypass duct that routed flow subsonically around an engine-mounted gearbox and diverted flow with high shock losses away from the fan tip. Two Reynolds-averaged Navier-Stokes codes were used for the analysis: an axisymmetric code called AVCS for the inlet and a three dimensional (3-D) code called SWIFT for the fan. The codes were coupled at a mixing plane boundary using a separate code for data exchange. The codes were used to determine the performance of the inlet/fan system at the design point and to predict the performance and operability of the system over the flight profile. At the design point the core inlet had a recovery of 96 percent, and the fan operated near its peak efficiency and pressure ratio. A large hub radial distortion generated in the inlet was not eliminated by the fan and could pose a challenge for subsequent booster stages. The system operated stably at all points along the flight profile. Reduced stall margin was seen at low altitude and Mach number where flow separated on the interior lips of the cowl and bypass ducts. The coupled analysis gave consistent solutions at all points on the flight profile that would be difficult or impossible to predict by analysis of isolated components.

Coupled Analysis of an Inlet and Fan for a Quiet Supersonic Aircraft

Science.gov (United States)

Chima, Rodrick V.; Conners, Timothy R.; Wayman, Thomas R.

2009-01-01

A computational analysis of a Gulfstream isentropic external compression supersonic inlet coupled to a Rolls-Royce fan was completed. The inlet was designed for a small, low sonic boom supersonic vehicle with a design cruise condition of M = 1.6 at 45,000 feet. The inlet design included an annular bypass duct that routed flow subsonically around an engine-mounted gearbox and diverted flow with high shock losses away from the fan tip. Two Reynolds-averaged Navier-Stokes codes were used for the analysis: an axisymmetric code called AVCS for the inlet and a 3-D code called SWIFT for the fan. The codes were coupled at a mixing plane boundary using a separate code for data exchange. The codes were used to determine the performance of the inlet/fan system at the design point and to predict the performance and operability of the system over the flight profile. At the design point the core inlet had a recovery of 96 percent, and the fan operated near its peak efficiency and pressure ratio. A large hub radial distortion generated in the inlet was not eliminated by the fan and could pose a challenge for subsequent booster stages. The system operated stably at all points along the flight profile. Reduced stall margin was seen at low altitude and Mach number where flow separated on the interior lips of the cowl and bypass ducts. The coupled analysis gave consistent solutions at all points on the flight profile that would be difficult or impossible to predict by analysis of isolated components.

Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Directory of Open Access Journals (Sweden)

Giuseppe Lo Giudice

2011-03-01

Full Text Available Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of subthreshold transpupillary thermotherapy (TTT in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC.Methods: Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA. Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW. Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results: The mean number of TTT sessions was 1.4 ± 0.5. All eyes were followed up for at least 6 months (mean 9.6 ± 3.2 standard deviation; range 6–12 months. The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P < 0.001. Mean optical coherence tomography (OCT central foveal thickness was significantly lower in all patients (P < 0.001 compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion: Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.Keywords: central serous chorioretinopathy, indocyanine green angiography, neurosensory detachment, transpupillary

[Functional results of cryosurgical procedures in rhegmatogenous retinal detachment including macula region - our experience].

Science.gov (United States)

Chrapek, O; Sín, M; Jirková, B; Jarkovský, J; Rehák, J

2013-10-01

Aim of this study is to evaluate retrospectively functional results of cryosurgical treatment of uncomplicated, idiopathic rhegmatogenous retinal detachment including macula region in phakic patients operated on at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc, Czech Republic, E.U., during the period 2002 -2013, and to evaluate the significance of the macula detachment duration for the final visual acuity. In the study group were included 56 eyes of 56 patients operated in the years 2003 - 2012 at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc. All patients were phakic and in all of them, the retinal detachment including the macula region was diagnosed. The mean follow-up period of the patients was 8,75 months. The initial and final visual acuity testing were performed. Comparing the initial and final visual acuity we rated the level of the visual acuity change. The result was stated as improved, if the visual acuity improved by 1 or more lines on the ETDRS chart. The result was rated as stabilized, if the visual acuity remained the same or it changed by 1 line of the ETDRS chart only. The result was evaluated as worsened, if the visual acuity decreased by 1 or more lines of the ETDRS chart. In the followed-up group, the authors compared visual acuity levels in patients with the macula detachment duration 10 days and 11 days. For the statistical evaluation of achieved results, the Mann - Whitney U test was used. The visual acuity improved in 49 (87 %), did not changed in 5 (9 %) and worsened in 2 (4 %) patients. The patients with macula detachment duration 10 days achieved statistically significant better visual acuity than patients with macula detachment duration 11 days. Patients with macula detachment duration 10 days have better prognosis for functional result than patients with macula detachment duration 11 days.

Classification of posterior vitreous detachment

OpenAIRE

Kakehashi, Akihiro; Takezawa, Mikiko; Akiba, Jun

2013-01-01

Akihiro Kakehashi,1 Mikiko Takezawa,1 Jun Akiba21Department of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, 2Kanjodori Eye Clinic, Asahikawa, JapanAbstract: Diagnosing a posterior vitreous detachment (PVD) is important for predicting the prognosis and determining the indication for vitreoretinal surgery in many vitreoretinal diseases. This article presents both classifications of a PVD by slit-lamp biomicroscopy and of a shallow PVD by optical coherence tomography...

Functional and environmental design of detached, low crest level breakwaters

International Nuclear Information System (INIS)

Bricio Garberi, L.; Negro Valdecantos, V.; Diez Gonzalez, J. J.; Lopez Gutierrez, J. S.

2010-01-01

The research work as presented in this article covers the design of detached breakwaters since they constitute a type of coastal defense work with which to combat many of the erosion problems found on beaches in a stable, sustainable fashion. The main aim of this work is to formulate a functional and environmental (non structural) method of design enabling the fundamental characteristics of a detached breakwater to be defined as a function of the effect it is wished to induce on the coast whilst meeting social demands and preserving or improving the quality of the littoral environment. The general applicability of the method is also sought by means of considering relations between variables od different natures (climatic, geomorphologic and geometric) influencing the changes experienced on the coast after the detached breakwater has been built. The study of the relations between the different variables is carried out on the data from a abase of nineteen actual, existing detached breakwaters on the Spanish Mediterranean coastline and follows a methodology based on the implementation of non-dimensional monomials and on a search for relations of dependency between them. Finally, a discussion on the results obtained lead to a proposal for a design method that uses some of the graphic relations found between the variables studied with which the aforesaid main objective is achieved. (Author) 9 refs.

Efficacy of ophthalmic solutions to detach adhering Pseudomonas aeruginosa from contact lenses

NARCIS (Netherlands)

Landa, AS; van der Mei, HC; van Rij, G; Busscher, HJ

Purpose. To compare the efficacies of two all-in-one contact lens (CL) cleaning solutions and a detergent mixture on the detachment of a pathogenic bacterium adhering to two types of contact lenses in the absence and presence of a tear film. Methods. Bacterial-detachment studies were carried out in

Risk of serous retinal detachment in patients with end-stage renal disease on dialysis.

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Yuh-Shin Chang

Full Text Available The aim of this retrospective, nationwide, matched cohort study was to investigate the association of serous retinal detachment with having end-stage renal disease (ESRD while on dialysis. The cohort study included 94,024 patients with ESRD on dialysis registered between January 2000 to December 2009 in the Taiwan National Health Insurance Research Database. An age- and sex-matched control group comprised 94,024 patients selected from the Taiwan Longitudinal Health Insurance Database 2000. Information for each patient was collected from the index date until December 2011. Twenty-seven ESRD patients and 11 controls developed serous retinal detachment (P < 0.001 during follow-up, demonstrating a significantly increased risk of serous retinal detachment in patients with ESRD on dialysis compared with controls (incidence rate ratio = 3.39, 95% confidence interval [CI] = 1.68-6.83. After adjustment for potential confounders, patients were 3.86 times more likely to develop serous retinal detachment than the full cohort (adjusted HR = 3.86, 95% CI = 1.15-12.96. In conclusion, patients with ESRD on dialysis demonstrate an increased risk of serous retinal detachment. Interdisciplinary collaboration between nephrologists and ophthalmologists is important to deal with serous retinal detachment in patients with ESRD on dialysis and prevent impairments of visual acuity.

Macular detachment associated with an optic pit: optical coherence tomography patterns and surgical outcomes.

Science.gov (United States)

Skaat, Alon; Moroz, Iris; Moisseiev, Joseph

2013-01-01

To describe the different optical coherence tomography (OCT) patterns in macular detachment associated with an optic disc pit and their long-term evolution following vitrectomy.
 The data of 5 patients (9-43 years of age) with unilateral macular detachment associated with an optic disc pit, who had at least 1 year of follow-up, were compiled. Pars plana vitrectomy combined with gas tamponade was performed as the primary procedure in all patients. The OCT scans, best-corrected visual acuity (BCVA), and anatomic outcomes were documented.
 Two main OCT patterns were identified: a multilayer schisis pattern and a serous detachment pattern. Patients with multilayer schisis pattern were older and demonstrated worse mean preoperative (20/160) and postoperative (20/50) BCVA compared to serous detachment pattern patients (20/30 and 20/20, respectively). An average of 2.3 procedures per patient was needed in the multilayer schisis pattern compared to just one procedure in the serous detachment pattern. In 3 patients, additional pneumatic retinopexy was performed with full resolution of the subretinal fluid achieved.
 Two distinct OCT patterns were observed in eyes with macular detachments with an optic pit, with different clinical features and prognoses. Excellent final visual acuity was obtained in all eyes, including those that required several surgical procedures.

Influence of Cell Detachment on the Respiration Rate of Tumor and Endothelial Cells

Science.gov (United States)

Danhier, Pierre; Copetti, Tamara; De Preter, Géraldine; Leveque, Philippe; Feron, Olivier; Jordan, Bénédicte F.; Sonveaux, Pierre; Gallez, Bernard

2013-01-01

Cell detachment is a procedure routinely performed in cell culture and a necessary step in many biochemical assays including the determination of oxygen consumption rates (OCR) in vitro. In vivo, cell detachment has been shown to exert profound metabolic influences notably in cancer but also in other pathologies, such as retinal detachment for example. In the present study, we developed and validated a new technique combining electron paramagnetic resonance (EPR) oximetry and the use of cytodex 1 and collagen-coated cytodex 3 dextran microbeads, which allowed the unprecedented comparison of the OCR of adherent and detached cells with high sensitivity. Hence, we demonstrated that both B16F10 melanoma cells and human umbilical vein endothelial cells (HUVEC) experience strong OCR decrease upon trypsin or collagenase treatments. The reduction of cell oxygen consumption was more pronounced with a trypsin compared to a collagenase treatment. Cells remaining in suspension also encounter a marked intracellular ATP depletion and an increase in the lactate production/glucose uptake ratio. These findings highlight the important influence exerted by cell adhesion/detachment on cell respiration, which can be probed with the unprecedented experimental assay that was developed and validated in this study. PMID:23382841

Influence of cell detachment on the respiration rate of tumor and endothelial cells.

Science.gov (United States)

Danhier, Pierre; Copetti, Tamara; De Preter, Géraldine; Leveque, Philippe; Feron, Olivier; Jordan, Bénédicte F; Sonveaux, Pierre; Gallez, Bernard

2013-01-01

Cell detachment is a procedure routinely performed in cell culture and a necessary step in many biochemical assays including the determination of oxygen consumption rates (OCR) in vitro. In vivo, cell detachment has been shown to exert profound metabolic influences notably in cancer but also in other pathologies, such as retinal detachment for example. In the present study, we developed and validated a new technique combining electron paramagnetic resonance (EPR) oximetry and the use of cytodex 1 and collagen-coated cytodex 3 dextran microbeads, which allowed the unprecedented comparison of the OCR of adherent and detached cells with high sensitivity. Hence, we demonstrated that both B16F10 melanoma cells and human umbilical vein endothelial cells (HUVEC) experience strong OCR decrease upon trypsin or collagenase treatments. The reduction of cell oxygen consumption was more pronounced with a trypsin compared to a collagenase treatment. Cells remaining in suspension also encounter a marked intracellular ATP depletion and an increase in the lactate production/glucose uptake ratio. These findings highlight the important influence exerted by cell adhesion/detachment on cell respiration, which can be probed with the unprecedented experimental assay that was developed and validated in this study.

Electron-detachment cross sections of halogen negative-ion projectiles for inertial confinement fusion

Science.gov (United States)

Sant'Anna, M. M.; Zappa, F.; Santos, A. C. F.; de Barros, A. L. F.; Wolff, W.; Coelho, L. F. S.; de Castro Faria, N. V.

2004-07-01

Negative-ion beams have recently been suggested as sources of high-energy heavy atoms to be used as drivers for inertial confinement fusion (ICF). Owing to their electron affinities limited to a few eV, anions can be efficiently photo-detached in the vicinity of the fusion chamber, with the resulting high-velocity neutral projectiles following ballistic trajectories towards the hydrogen pellet target. Electron-detachment cross sections are needed as parameters to estimate the beam attenuation in the path from the ion source to the hydrogen pellet. Halogen anions are possible projectile choices. In this paper we present experimental data for total electron-detachment cross sections for F-, Cl-, Br- and I- ions incident on N2, in the 0.94-74 keV u-1 energy range. Our measurements can benchmark theory on anion electron detachment at intermediate to high velocities. Comparison between different projectiles shows very similar collision velocity dependencies. A simple geometrical scaling is presented, providing an estimate for electron-detachment cross sections at the MeV u-1 energy range. The presented scaling indicates that the vacuum requirements due to the use of halogen anions for ICF are less critical than previously suggested.

Electron-detachment cross sections of halogen negative-ion projectiles for inertial confinement fusion

International Nuclear Information System (INIS)

Sant'Anna, M M; Zappa, F; Santos, A C F; Barros, A L F de; Wolff, W; Coelho, L F S; Faria, N V de Castro

2004-01-01

Negative-ion beams have recently been suggested as sources of high-energy heavy atoms to be used as drivers for inertial confinement fusion (ICF). Owing to their electron affinities limited to a few eV, anions can be efficiently photo-detached in the vicinity of the fusion chamber, with the resulting high-velocity neutral projectiles following ballistic trajectories towards the hydrogen pellet target. Electron-detachment cross sections are needed as parameters to estimate the beam attenuation in the path from the ion source to the hydrogen pellet. Halogen anions are possible projectile choices. In this paper we present experimental data for total electron-detachment cross sections for F - , Cl - , Br - and I - ions incident on N 2 , in the 0.94-74 keV u -1 energy range. Our measurements can benchmark theory on anion electron detachment at intermediate to high velocities. Comparison between different projectiles shows very similar collision velocity dependencies. A simple geometrical scaling is presented, providing an estimate for electron-detachment cross sections at the MeV u -1 energy range. The presented scaling indicates that the vacuum requirements due to the use of halogen anions for ICF are less critical than previously suggested

Evaluation of PM-10 commercial inlets for new surveillance air sampler

International Nuclear Information System (INIS)

Langer, G.

1987-01-01

The purpose of this project is to adapt an existing sampling inlet or develop a new one to collect airborne dust particles <10-μm aerodynamic equivalent diameter. These inlets are necessary to meet new EPA and DOE guidelines for surveillance of nuclear facilities

Electron detachment by H- + H- collisions

International Nuclear Information System (INIS)

Chibisov, M.I.; Yavlinskii, Yu.N.

1994-01-01

The autoionization channels for electrons detachment in collisions of two negative hydrogen ions in the energy range 300 - 500 eV and > 500 eV are investigated. In small energy range at large inter-ion distances the asymptotic approximation is used; at high energies - perturbation theory and classical motion are used. 18 refs., 3 figs

Prophylactic treatment of the fellow eye of patients with retinal detachment: a retrospective study.

Science.gov (United States)

Avitabile, Teresio; Bonfiglio, Vincenza; Reibaldi, Michele; Torrisi, Benedetto; Reibaldi, Alfredo

2004-03-01

Controversy exists over the prophylactic treatment of predisposing lesions to prevent retinal detachment. Seven hundred sixty consecutive phakic fellow eyes with rhegmatogenous retinal detachment in the first eye were examined by the same vitreoretinal surgeon before detachment surgery and for a follow-up period ranging from 1 to 72 months, with a mean of 36 months. During this period, in 305 fellow eyes (40.1%) predisposing retinal lesions were present and prophylactic treatments (photocoagulation, cryotherapy or scleral buckle) were performed independently of vitreous status. The results were then compared with the incidence of bilateral RD without prophylaxis reported in Folk and Burton's study of 1982; the two study's data were well matched and showed no significant difference in regards to age, sex, incidence myopia > or =-2.5 and incidence of lattice degeneration. The objective was to investigate whether or not prophylactic treatment is able to avert retinal detachment in the fellow eye. The age of the patients with peripheral retinal lesions was correlated inversely with the presence of myopia. Nine eyes out of 305 eyes treated (2.9%) developed a retinal detachment, reducing the rate of bilateral retinal detachment to 1.2% (9 eyes out of 760). This incidence of bilaterality (1.2%) was lower than the incidence of retinal detachment in fellow eyes not prophylactically treated as reported in the literature, and there exists a highly statistically significant difference between this study's data of 1.2% after prophylaxis and a 13.4% rate of bilaterality as reported by Folk without prophylaxis (P=0.0000).

Meniscus Shapes in Detached Bridgman Growth

Science.gov (United States)

Volz, M. P.; Mazuruk, K

2010-01-01

In detached Bridgman crystal growth, most of the melt is in contact with the ampoule wall, but the crystal is separated from the wall by a small gap, typically 1-100 micrometers. A liquid free surface, or meniscus, bridges across this gap at the position of the melt-crystal interface. Meniscus shapes have been calculated for the case of detached Bridgman growth in cylindrical ampoules by solving the Young-Laplace equation. Key parameters affecting meniscus shapes are the growth angle, contact angle of the meniscus to the ampoule wall, the pressure differential across the meniscus, and the Bond number, a measure of the ratio of gravitational to capillary forces. In general, for specified values of growth and contact angles, solutions exist only over a finite range of pressure differentials. For intermediate values of the Bond number, there are multiple solutions to the Young-Laplace equations. There are also cases where, as a function of pressure differential, existence intervals alternate with intervals where no solutions exist. The implications of the meniscus shape calculations on meniscus stability are discussed.

Performance and Adaptive Surge-Preventing Acceleration Prediction of a Turboshaft Engine under Inlet Flow Distortion

Directory of Open Access Journals (Sweden)

Cao Dalu

2017-01-01

Full Text Available The intention of this paper is to research the inlet flow distortion influence on overall performance of turboshaft engine and put forward a method called Distortion Factor Item (DFI to improve the fuel supply plan for surge-preventing acceleration when turboshaft engine suddenly encounters inlet flow distortion. Based on the parallel compressor theory, steady-state and transition-state numerical simulation model of turboshaft engine with sub-compressor model were established for researching the influence of inlet flow distortion on turboshaft engine. This paper made a detailed analysis on the compressor operation from the aspects of performance and stability, and then analyzed the overall performance and dynamic response of the whole engine under inlet flow distortion. Improved fuel supply plan with DFI method was applied to control the acceleration process adaptively when encountering different inlet flow distortion. Several simulation examples about extreme natural environments were calculated to testify DFI method’s environmental applicability. The result shows that the inlet flow distortion reduces the air inflow and decreases the surge margin of compressor, and increase the engine exhaust loss. Encountering inlet flow distortion has many adverse influences such as sudden rotor acceleration, turbine inlet temperature rise and power output reduction. By using improved fuel supply plan with DFI, turboshaft engine above-idle acceleration can avoid surge effectively under inlet flow distortion with environmental applicability.

Microjet flow control in an ultra-compact serpentine inlet

Directory of Open Access Journals (Sweden)

Da Xingya

2015-10-01

Full Text Available Microjets are used to control the internal flow to improve the performance of an ultra-compact serpentine inlet. A highly offset serpentine inlet with length-to-diameter ratio of 2.5 is designed and static tests are conducted to analyze the internal flow characteristics in terms of pressure recovery, distortion and flow separation. Flow separation is encountered in the second S-turn, and two strong counter-rotating vortices are formed at the aerodynamic interface plane (AIP face which occupy a quarter of the outlet area and result in severe pressure loss and distortion. A flow control model employing a row of microjets in the second turn is designed based on the internal flow characteristics and simplified CFD simulations. Flow control tests are conducted to verify the control effectiveness and understand the characteristics as a function of inlet throat Mach number, injection mass flow ratio, jet Mach number and momentum coefficient. At all test Mach numbers, microjet flow control (MFC effectively improves the recovery and reduces the distortion intensity. Between inlet throat Mach number 0.2 and 0.5, the strong flow separation in the second S-turn is suppressed at an optimum jet flow ratio of less than 0.65%, resulting in a maximum improvement of 4% for pressure recovery coefficient and a maximum decrease of 75% for circumferential distortion intensity at cruise. However, in order to suppress the flow separation, the injection rate should retain in an effective range. When the injection rate is higher than this range, the flow is degraded and the distortion contour is changed from 90° circumferential distortion pattern to 180° circumferential distortion pattern. Detailed data analysis shows that this optimum flow ratio depends on inlet throat Mach number and the momentum coefficient affects the control effectiveness in a dual stepping manner.

An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment.

Science.gov (United States)

Mathew, David J; Sarma, Saurabh Kumar; Basaiawmoit, Jennifer V

2016-07-01

Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment. An asymptomatic 35-year-old lady with minimal refractive error was found to have extensive lattice degeneration, peripheral retinal detachment and fibrotic changes peripherally with elevation of retinal vessels on dilated retinal examination. There were also areas of white without pressure, chorioretinal scarring and retinal breaks. All the changes were limited to beyond the equator but were found to span 360 degrees. She was treated with barrage laser all around to prevent extension of the retinal detachment posteriorly. She remained stable till her latest follow-up two years after the barrage laser. This case is reported for its rarity with a discussion of the probable differential diagnoses. To the best of our knowledge, this is the first report of such findings in lattice degeneration.

Psychological detachment from work during non-work time: linear or curvilinear relations with mental health and work engagement?

Science.gov (United States)

Shimazu, Akihito; Matsudaira, Ko; Jonge, Jan DE; Tosaka, Naoya; Watanabe, Kazuhiro; Takahashi, Masaya

2016-06-10

This study examined whether a higher level of psychological detachment during non-work time is associated with better employee mental health (Hypothesis 1), and examined whether psychological detachment has a curvilinear relation (inverted U-shaped pattern) with work engagement (Hypothesis 2). A large cross-sectional Internet survey was conducted among registered monitors of an Internet survey company in Japan. The questionnaire included scales for psychological detachment, employee mental health, and work engagement as well as for job characteristics and demographic variables as potential confounders. The hypothesized model was tested with moderated structural equation modeling techniques among 2,234 respondents working in the tertiary industries with regular employment. Results showed that psychological detachment had curvilinear relations with mental health as well as with work engagement. Mental health improved when psychological detachment increased from a low to higher levels but did not benefit any further from extremely high levels of psychological detachment. Work engagement showed the highest level at an intermediate level of detachment (inverted U-shaped pattern). Although high psychological detachment may enhance employee mental health, moderate levels of psychological detachment are most beneficial for his or her work engagement.

Stability analysis for tidal inlets of Thuan An and Tu Hien using Escoffier diagram

NARCIS (Netherlands)

Lam, N.T.; Verhagen, H.J.; Van der Wegen, M.

2004-01-01

Stability analysis of tidal inlets is very important in providing knowledge on the behaviour of tidal inlet and lagoon systems. The analysis results can help to plan and manage the system effectively as well as to provide information for stability design of the inlets. This paper presents a method

Detachment dynamics of colloidal spheres with adhesive interactions

Science.gov (United States)

Bergenholtz, J.

2018-04-01

Escape of colloidal-size particles from various kinds of solids, such as aggregates and surfaces, occurs in a wide variety of settings of both fundamental and applied scientific interest. In this paper an exact solution for the detachment of adhesive spheres from each other by means of diffusion is presented. The solution takes into account repeated detachment and reattachment events in the course of time on the way toward the permanently separated state. For strongly adhesive spheres this state is approached in an exponential manner essentially regardless of how the bound state is specified. The analytical solution is shown to capture semiquantitatively the escape from more realistic potential wells using a mapping procedure whereby equality of second virial coefficients is imposed.

Variations of posterior vitreous detachment

OpenAIRE

Kakehashi, A.; Kado, M.; Akiba, J.; Hirokawa, H.

1997-01-01

AIMS—To identify variations in posterior vitreous detachment (PVD) and establish a clinical classification system for PVD.
METHODS—400 consecutive eyes were examined using biomicroscopy and vitreous photography and classified the PVD variations—complete PVD with collapse, complete PVD without collapse, partial PVD with thickened posterior vitreous cortex (TPVC), or partial PVD without TPVC.
RESULTS—In each PVD type, the most frequently seen ocular pathologies were as follows: in complete PVD ...

Mechanism of bubble detachment from vibrating walls

Energy Technology Data Exchange (ETDEWEB)

Kim, Dongjun; Park, Jun Kwon, E-mail: junkeun@postech.ac.kr; Kang, Kwan Hyoung [Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), San 31, Hyoja-dong, Pohang 790-784 (Korea, Republic of); Kang, In Seok [Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), San 31, Hyoja-dong, Pohang 790-784 (Korea, Republic of)

2013-11-15

We discovered a previously unobserved mechanism by which air bubbles detach from vibrating walls in glasses containing water. Chaotic oscillation and subsequent water jets appeared when a wall vibrated at greater than a critical level. Wave forms were developed at water-air interface of the bubble by the wall vibration, and water jets were formed when sufficiently grown wave-curvatures were collapsing. Droplets were pinched off from the tip of jets and fell to the surface of the glass. When the solid-air interface at the bubble-wall attachment point was completely covered with water, the bubble detached from the wall. The water jets were mainly generated by subharmonic waves and were generated most vigorously when the wall vibrated at the volume resonant frequency of the bubble. Bubbles of specific size can be removed by adjusting the frequency of the wall's vibration.

Improved Hypersonic Inlet Performance Using Validated Strut Compression Designs

Science.gov (United States)

Bulman, M. J.; Stout, P. W.; Fernandez, R.

1997-01-01

Aerojet is currently executing two Strutjet propulsion contracts: one a Rocket Based Combined Cycle (RBCC) engine for a NASA-Marshall Space Flight Center (MSFC) Advanced Reusable Transportation Technology (ARTT) program, the second a Dual Mode Ram/Scramjet engine for a USAF Wright Laboratories Storable Fuel Scramjet Flow Path Concepts program. The engines employed in both programs operate at supersonic and low hypersonic speeds and use inlets employing forebody external and sidewall compression. Aerojet has developed and validated a successful design methodology applicable to these inlet types. Design features include an integrated vehicle forebody, external side compression struts, strut sidewall and throat bleed, a throat shock trap, and variable geometry internal contraction. Computation Fluid Dynamic (CFD) predictions and test data show these inlets allow substantially increased flow turning angles over other designs. These increased flow turning angles allow shorter and lighter engines than current designs, which in turn enables higher performing vehicles with broad operating characteristics. This paper describes the designs of two different inlets evaluated by the NASA-MSFC and USAF programs, discusses the results of wind tunnel tests performed by NASA-Lewis Research Center, and provides correlations of test data with CFD predictions. Parameters of interest include low Mach number starting capability, start sensitivity as a function of back pressure at various contraction ratios, flow turning angles, strut and throat bleed effects, and pressure recovery at various Mach numbers.

Swozzle based burner tube premixer including inlet air conditioner for low emissions combustion

Science.gov (United States)

Tuthill, Richard Sterling; Bechtel, II, William Theodore; Benoit, Jeffrey Arthur; Black, Stephen Hugh; Bland, Robert James; DeLeonardo, Guy Wayne; Meyer, Stefan Martin; Taura, Joseph Charles; Battaglioli, John Luigi

2002-01-01

A burner for use in a combustion system of a heavy-duty industrial gas turbine includes a fuel/air premixer having an air inlet, a fuel inlet, and an annular mixing passage. The fuel/air premixer mixes fuel and air into a uniform mixture for injection into a combustor reaction zone. The burner also includes an inlet flow conditioner disposed at the air inlet of the fuel/air premixer for controlling a radial and circumferential distribution of incoming air. The pattern of perforations in the inlet flow conditioner is designed such that a uniform air flow distribution is produced at the swirler inlet annulus in both the radial and circumference directions. The premixer includes a swozzle assembly having a series of preferably air foil shaped turning vanes that impart swirl to the airflow entering via the inlet flow conditioner. Each air foil contains internal fuel flow passages that introduce natural gas fuel into the air stream via fuel metering holes that pass through the walls of the air foil shaped turning vanes. By injecting fuel in this manner, an aerodynamically clean flow field is maintained throughout the premixer. By injecting fuel via two separate passages, the fuel/air mixture strength distribution can be controlled in the radial direction to obtain optimum radial concentration profiles for control of emissions, lean blow outs, and combustion driven dynamic pressure activity as machine and combustor load are varied.

Geometry of tidal inlet systems : A key factor for the net sediment transport in tidal inlets

NARCIS (Netherlands)

Ridderinkhof, W.; de Swart, H. E.; van der Vegt, M.; Alebregtse, N. C.; Hoekstra, P.

2014-01-01

The net transport of sediment between the back-barrier basin and the sea is an important process for determining the stability of tidal inlet systems. Earlier studies showed that in a short basin, tidal flats favor peak ebb-currents stronger than peak flood currents, implying export of coarse

Management of retinal detachment in block related globe perforation with pneumatic retinopexy

Directory of Open Access Journals (Sweden)

Karandeep Rishi

2013-01-01

Full Text Available Retinal detachment after ocular perforation related to local anesthesia is a common complication, which is usually associated with a poor prognosis despite complex vitreoretinal surgical procedures. We report a case of 62-year-old male with cataract surgery done 4 weeks back with nasal retinal detachment with a posterior break. Pneumatic retinopexy was performed and laser barrage of the breaks was done the next day when the retina got attached. A vision of 20/30 was achieved at the end of 2 months. To the best of our knowledge, this is a first case report in literature where pneumatic retinopexy was used to manage a retinal detachment caused by block-related perforation.

Thermodynamic assessment of impact of inlet air cooling techniques on gas turbine and combined cycle performance

International Nuclear Information System (INIS)

Mohapatra, Alok Ku; Sanjay

2014-01-01

The article is focused on the comparison of impact of two different methods of inlet air cooling (vapor compression and vapor absorption cooling) integrated to a cooled gas turbine based combined cycle plant. Air-film cooling has been adopted as the cooling technique for gas turbine blades. A parametric study of the effect of compressor pressure ratio, compressor inlet temperature (T i , C ), turbine inlet temperature (T i , T ), ambient relative humidity and ambient temperature on performance parameters of plant has been carried out. Optimum T i , T corresponding to maximum plant efficiency of combined cycle increases by 100 °C due to the integration of inlet air cooling. It has been observed that vapor compression cooling improves the efficiency of gas turbine cycle by 4.88% and work output by 14.77%. In case of vapor absorption cooling an improvement of 17.2% in gas cycle work output and 9.47% in gas cycle efficiency has been observed. For combined cycle configuration, however, vapor compression cooling should be preferred over absorption cooling in terms of higher plant performance. The optimum value of compressor inlet temperature has been observed to be 20 °C for the chosen set of conditions for both the inlet air cooling schemes. - Highlights: • Inlet air cooling improves performance of cooled gas turbine based combined cycle. • Vapor compression inlet air cooling is superior to vapor absorption inlet cooling. • For every turbine inlet temperature, there exists an optimum pressure ratio. • The optimum compressor inlet temperature is found to be 293 K

Adhesion mechanism of a gecko-inspired oblique structure with an adhesive tip for asymmetric detachment

International Nuclear Information System (INIS)

Sekiguchi, Yu; Sato, Chiaki; Takahashi, Kunio

2015-01-01

An adhesion model of an oblique structure with an adhesive tip is proposed by considering a limiting stress for adhesion to describe the detachment mechanism of gecko foot hairs. When a force is applied to the root of the oblique structure, normal and shear stresses are generated at contact and the adhesive tip is detached from the surface when reaching the limiting stress. An adhesion criterion that considers both the normal and shear stresses is introduced, and the asymmetric detachment of the oblique structure is theoretically investigated. In addition, oblique beam array structures are manufactured, and an inclination effect of the structure on the asymmetric detachment is experimentally verified. (paper)

Experimental Investigation of a Forward Swept Rotor in a Multistage Fan with Inlet Distortion

Directory of Open Access Journals (Sweden)

Aspi R. Wadia

2011-01-01

Full Text Available Previous studies of transonic swept rotors in single stage fans have demonstrated the potential of significant improvements in both efficiency and stall margin with forward swept blading. This paper extends the assessment of the payoff derived from forward sweep to multistage configurations. The experimental investigation compare two builds of an advanced two-stage fan configuration tested alternately with a radial and a forward swept stage 1 blade. In the two-stage evaluations, the testing was extended to include the effect on inlet flow distortion. While the common second stage among the two builds prevented the overall fan from showing clean inlet performance and stability benefits with the forward swept rotor 1, this configuration did demonstrate superior front stage efficiency and tolerance to inlet distortion. Having obtained already low distortion sensitivity with the radial rotor 1 configuration relative to current production military fan standards, the sensitivity to inlet distortion was halved with the forward swept rotor 1 configuration. In the case of the 180-degree one-per-rev distortion pattern, the two-stage configuration was evaluated both with and without inlet guide vanes (IGVs. The presence of the inlet guide vanes had a profound impact in lowering the two-stage fan's sensitivity with inlet distortion.

Shoreline response to detached breakwaters in prototype

NARCIS (Netherlands)

Khuong, T.C.

2016-01-01

An accurate prediction of shoreline changes behind detached breakwaters is, in regard to the adjustment to the environmental impact, still a challenge for designers and coastal managers. This research is expected to fill the gaps in the estimation of shoreline changes by developing new and

Long-term effects of short-term retinal bleb detachments in rabbits.

Science.gov (United States)

Ivert, Lena; Kjeldbye, Hild; Gouras, Peter

2002-03-01

To examine the effects of saline-induced bleb detachments in rabbit retina. Retinal bleb detachments were produced by the injection of 50 microl of balanced salt solution (BSS) into the subretinal space of one eye of each of six rabbits using a glass pipette with a flat tip, 50 microm in diameter. The retina was examined by biomicroscopy, scanning laser ophthalmoscopy (SLO), auto-fluorescence and simultaneous fluorescein and indocyanine green (ICG) angiography. Histological examination was carried out at 1, 2, 3 and 4 months after surgery. All rabbits showed leakage of fluorescein for at least a day after detachment, but within 1 month the leakage ceased. ICG staining developed gradually at the level of the RPE or Bruch's membrane near sites of previous staining. Lipofuscin fluorescence also developed gradually around areas of staining. Histology revealed the source of the excessive lipofuscin to be in the RPE layer, especially in cells migrating away from Bruch's membrane. Short-term bleb detachments cause a transient breakdown in the blood-retinal barrier, long-term ICG staining at or deep to the RPE layer, hyperlipofuscinosis and migration of the RPE. The abnormal lipofuscin accumulation is apparent on fluorescence ophthalmoscopy and can be confused with markers such as green fluorescent protein.

Observation of multiphoton detachment of the H/sup -/ ion

International Nuclear Information System (INIS)

Tang, C.Y.; Harris, P.G.; Mohagheghi, A.H.; Los Alamos National Laboratory, Los Alamos, New Mexico 87545; Cohen Mechanical Design, Broomall, Pennsylvania 19008; The University of Connecticut, Storrs, Connecticut 06268; Western Washington University, Bellingham, Washington 98225)

1989-01-01

We have observed nonresonant multiphoton electron detachment of H/sup -/ ions in moderately intense (a few tens of GW/cm 2 ) laser fields. A well-collimated beam of H/sup -/ ions with an energy of 581 MeV was intersected by focused 10.6-μm radiation from a pulsed CO 2 laser. The center-of-mass photon energy was tuned using the relativistic Doppler shift so that the minimum number of simultaneous photons required for electron detachment ranged from three to sixteen. Definite signals were observed for the minimum photon number ranging from three to eight. Our preliminary results show evidence for structure in the relative total cross section

Boundary conditions for free surface inlet and outlet problems

KAUST Repository

Taroni, M.

2012-08-10

We investigate and compare the boundary conditions that are to be applied to free-surface problems involving inlet and outlets of Newtonian fluid, typically found in coating processes. The flux of fluid is a priori known at an inlet, but unknown at an outlet, where it is governed by the local behaviour near the film-forming meniscus. In the limit of vanishing capillary number Ca it is well known that the flux scales with Ca 2/3, but this classical result is non-uniform as the contact angle approaches π. By examining this limit we find a solution that is uniformly valid for all contact angles. Furthermore, by considering the far-field behaviour of the free surface we show that there exists a critical capillary number above which the problem at an inlet becomes over-determined. The implications of this result for the modelling of coating flows are discussed. © 2012 Cambridge University Press.

Effect of blade sweep on inlet flow in axial compressor cascades

Directory of Open Access Journals (Sweden)

Hao Chang

2015-02-01

Full Text Available This paper presents comparative numerical studies to investigate the effects of blade sweep on inlet flow in axial compressor cascades. A series of swept and straight cascades was modeled in order to obtain a general understanding of the inlet flow field that is induced by sweep. A computational fluid dynamics (CFD package was used to simulate the cascades and obtain the required three-dimensional (3D flow parameters. A circumferentially averaged method was introduced which provided the circumferential fluctuation (CF terms in the momentum equation. A program for data reduction was conducted to obtain a circumferentially averaged flow field. The influences of the inlet flow fields of the cascades were studied and spanwise distributions of each term in the momentum equation were analyzed. The results indicate that blade sweep does affect inlet radial equilibrium. The characteristic of radial fluid transfer is changed and thus influencing the axial velocity distributions. The inlet flow field varies mainly due to the combined effect of the radial pressure gradient and the CF component. The axial velocity varies consistently with the incidence variation induced by the sweep, as observed in the previous literature. In addition, factors that might influence the radial equilibrium such as blade camber angles, solidity and the effect of the distance from the leading edge are also taken into consideration and comparatively analyzed.

Optimization of inlet plenum of A PBMR using surrogate modeling

International Nuclear Information System (INIS)

Lee, Sang-Moon; Kim, Kwang-Yong

2009-01-01

The purpose of present work is to optimize the design of inlet plenum of PBMR type gas cooled nuclear reactor numerically using a combining of three-dimensional Reynolds-averaged Navier-Stokes (RANS) analysis and surrogate modeling technique. Shear stress transport (SST) turbulence model is used as a turbulence closure. Three geometric design variables are selected, namely, rising channel diameter to plenum height ratio, aspect ratio of the plenum cross section, and inlet port angle. The objective function is defined as a linear combination of uniformity of three-dimensional flow distribution term and pressure drop in the inlet plenum and rising channels of PBMR term with a weighting factor. Twenty design points are selected using Latin-hypercube method of design of experiment and objective function values are obtained at each design point using RANS solver. (author)

Onyx embolization with the Apollo detachable tip microcatheter: A single-center experience.

Science.gov (United States)

Miller, Timothy R; Giacon, Luciano; Kole, Matthew J; Chen, Rong; Jindal, Gaurav; Gandhi, Dheeraj

2018-06-01

Purpose The Apollo Onyx Delivery Microcatheter (Ev3, Irvine, CA) is a detachable-tip microcatheter that was developed to reduce the risk of microcatheter entrapment during ethylene-vinyl alcohol copolymer (Onyx) embolizations. We report our experience with the microcatheter in a variety of neurointerventional procedures. Methods We retrospectively reviewed all Onyx embolizations performed in the head, neck, and spine using the Apollo Onyx Delivery Microcatheter from its introduction at our institution in July 2014 to August 2016. Information regarding patient diagnoses, procedural details, as well as clinical outcomes were obtained from the electronic medical record, procedure reports, and relevant angiographic imaging. Results A total of 58 arterial pedicle Onyx embolizations were performed in 37 patients. There were no cases of microcatheter entrapment, early/inadvertent tip detachment, or vessel injury upon removal of the device. There were two instances (3.5%) of leakage of Onyx from the microcatheter detachment site during embolization, which did not result in adverse sequelae. Clinical outcomes were excellent, with nearly all embolizations achieving the intended goal. In multivariate analysis, length of Onyx reflux along the microcatheter tip and utilization of a higher viscosity agent, Onyx 34, were significantly associated with tip detachment. Conclusion The use of the Apollo Microcatheter is both safe and effective during neurointerventional embolizations using Onyx. Leakage of liquid embolic agent from the detachment site is an infrequent technical complication that may be encountered with the device.

Influence of inlet water on the biotic and abiotic variables in a fish pond

Directory of Open Access Journals (Sweden)

L. H. Sipaúba-Tavares

Full Text Available Abstract The effects of treated and untreated water inlets with macrophytes on the improvement of water quality and zooplankton community were evaluated in a fish pond with continuous water flow. Water and zooplankton samples were retrieved at four sites during nine months. There were differences (p<0.01 between inlet water from fish pond and inlet water from canal with macrophytes, featuring higher concentrations of nutrient load, mainly TAN and TP in the former. The inlet water from fish pond contained a higher number of abundant species (9 species, whilst the water supply from the canal with macrophytes had a greater richness (31 species of zooplankton species. Results showed that inlet water without macrophytes directly affected the characteristics of the water column and the dominance of zooplankton species such as Thermocyclops decipiens, and greater abundance of Rotifera species. Since aquatic plants in the inlet water of fish pond analyzed showed lower allochthonous material loads from the previous fish pond, the management adopted with macrophytes may be applied to avoid eutrophication risks, common in farm ponds.

Investigation of Unsteady Flow Interaction Between an Ultra-Compact Inlet and a Transonic Fan

Science.gov (United States)

Hah, Chunill; Rabe, Douglas; Scribben, Angie

2015-01-01

In the present study, unsteady flow interaction between an ultra-compact inlet and a transonic fan stage is investigated. Future combat aircraft require ultra-compact inlet ducts as part of an integrated, advanced propulsion system to improve air vehicle capability and effectiveness to meet future mission needs. The main purpose of the study is to advance the current understanding of the flow interaction between two different ultra-compact inlets and a transonic fan for future design applications. Both URANS and LES approaches are used to calculate the unsteady flow field and are compared with the available measured data. The present study indicates that stall inception is mildly affected by the distortion pattern generated by the inlet with the current test set-up. The numerical study indicates that the inlet distortion pattern decays significantly before it reaches the fan face for the current configuration. Numerical results with a shorter distance between the inlet and fan show that counter-rotating vortices near the rotor tip due to the serpentine diffuser affects fan characteristics significantly.

Prediction of the Inlet Nozzle Velocity Profiles for the CANDU-6 Moderator Analysis

International Nuclear Information System (INIS)

Yoon, Churl; Park, Joo Hwan

2006-01-01

For the moderator analysis of the CANDU reactors in Korea, predicting local moderator subcooling in the Calandria vessels is one of the main concerns for the estimation of heat sink capability of moderator under LOCA transients. The moderator circulation pattern is determined by the combined forces of the inlet jet momentum and the buoyancy flow. Even though the inlet boundary condition plays an important role in determining the moderator circulations, no measured data of detailed inlet velocity profiles is available. The purpose of this study is to produce the velocity profiles at the inlet nozzles by a CFD simulation. To produce the velocity vector fields at the inlet nozzle surfaces, the internal flows in the nozzle assembly were simulated by using a commercial CFD code, CFX-5.7. In the reference, the analytical capability of CFX-5.7 had been estimated by a validation of the CFD code against available experimental data for separate flow phenomena. Various turbulence models and grid spacing had been also tested. In the following section, the interface treatment between the computational domains would be explained. In section 3, the inlet nozzle flow through the CANDU moderator nozzle assembly was predicted by using the obtained technology of the CFD simulation

Efficient energy recovering air inlet system for an internal combustion engine

NARCIS (Netherlands)

2011-01-01

An air inlet system (10) for an internal combustion engine (200) is provided. The air inlet system comprises an air intake port (20), an air output port (30) for providing air for a combustion chamber (202) of the combustion engine (200), and a turbine (40). The turbine (40) is situated in between

Efficient energy recovering air inlet system for an international combustion engine

NARCIS (Netherlands)

2013-01-01

An air inlet system (10) for an internal combustion engine (200) is provided. The air inlet system comprises an air intake port (20), an air output port (30) for providing air for a combustion chamber (202) of the combustion engine (200), and a turbine (40). The turbine (40) is situated in between

Bilateral Simultaneous Rhegmatogenous Retinal Detachment following Laser in situ Keratomileusis

Directory of Open Access Journals (Sweden)

Erhan Yumusak

2016-06-01

Full Text Available A 21-year-old woman developed simultaneous rhegmatogenous retinal detachment after laser in situ keratomileusis (LASIK in both eyes. She underwent pars plana vitrectomy surgery combined with endolaser photocoagulation and silicone oil tamponade in the right eye. A week later, pneumatic retinopexy was done in the left eye. As the retinal tear did not seal, 360° scleral buckling surgery was performed and retina was attached. Bilateral simultaneous rhegmatogenous retinal detachment after LASIK for correction of myopia can be a serious complication. Patients should be informed about the possibility of this complication.

Between Involvement and Detachment

DEFF Research Database (Denmark)

Thomasen, Gry

that the Department of State attempted a ‘political bargain’, with which the allies would be given political consultation and a détente in return for re-commitment to integration, whereas the Acheson Committee proposed a détente and deterrence formula in NATO to the overcome this perceived alliance disintegration....... Thus the US proposed the Harmel formula before Harmel. In general, the developments in Western Europe put the Johnson administration in a state of alarm, and the European allies therefore had a larger impact on America’s policies, except in the essentially detached nuclear policy, which...

Inlet throttling effect on the boiling two-phase flow stability in a natural circulation loop with a chimney

International Nuclear Information System (INIS)

Furuya, M.; Inada, F.; Yasuo, A.

2001-01-01

Experiments have been conducted to investigate an effect of inlet restriction on the thermal-hydraulic stability. A Test facility used in this study was designed and constructed to have non-dimensional values that are nearly equal to those of natural circulation BWR. Experimental results showed that driving force of the natural circulation at the stability boundary was described as a function of heat flux and inlet subcooling independent of inlet restriction. In order to extend experimental database regarding thermal-hydraulic stability to different inlet restriction, numerical analysis was carried out based on the homogeneous flow model. Stability maps in reference to the core inlet subcooling and heat flux were presented for various inlet restrictions using the above-mentioned function. Instability region during the inlet subcooling shifted to the higher inlet subcooling with increasing inlet restriction and became larger with increasing heat flux. (orig.)

Experimental investigation of a two-inlet air-based building integrated photovoltaic/thermal (BIPV/T) system

International Nuclear Information System (INIS)

Yang, Tingting; Athienitis, Andreas K.

2015-01-01

Highlights: • BIPV/T system thermal efficiency is 5% higher using two inlets compared to one. • BIPV/T thermal efficiency is 7.6% higher using semi-transparent than opaque PV. • Detailed air temperature profile in BIPV/T channel is obtained. • Nusselt number correlations are developed. - Abstract: An experimental study of thermal characteristics of a novel two-inlet air-based open-loop building integrated photovoltaic/thermal (BIPV/T) system using a full-scale solar simulator is presented. Experimental prototypes of one-inlet and two-inlet BIPV/T systems were constructed for conducting comparative experiments. Variations of BIPV/T systems are also investigated including systems employing opaque mono-crystalline silicon photovoltaic (PV) panels and systems employing semi-transparent mono-crystalline PV panels. Experimental results demonstrate that an equivalent two-inlet system with frameless PV panels can increase the thermal efficiency by 5% compared to a conventional one-inlet system, and that the BIPV/T system with semi-transparent PV panels achieves 7.6% higher thermal efficiency due to the absorption of some solar radiation at the bottom surface in the BIPV/T system cavity. Also, the two-inlet BIPV/T design is easily implemented and does not add significant cost. Detailed air temperature measurements reveal that the mixing of the warm outlet air from the first section and the cool ambient air drawn in from the second inlet contributes to the improved performance of the two-inlet system. Based on a thermal network model of the BIPV/T system and experimental data, correlations are developed for the convective heat transfer coefficients in the two sections. These are necessary for further analysis and development of BIPV/T system with multiple inlets.

76 FR 24513 - Public Land Order No. 7765; Partial Revocation Jupiter Inlet Lighthouse Withdrawal; Florida

Science.gov (United States)

2011-05-02

...] Public Land Order No. 7765; Partial Revocation Jupiter Inlet Lighthouse Withdrawal; Florida AGENCY... as part of the Jupiter Inlet Lighthouse Outstanding Natural Area. DATES: Effective Date: May 2, 2011... U.S.C. 1787), which created the Jupiter Inlet Lighthouse Outstanding Natural Area, and which...

Posterior vitreous detachment - prevalence of and risk factors for retinal tears

Directory of Open Access Journals (Sweden)

Bond-Taylor M

2017-09-01

Full Text Available Martin Bond-Taylor,1 Gunnar Jakobsson,1,2 Madeleine Zetterberg1,2 1Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, 2Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden Purpose: The present study aimed to describe clinical characteristics of patients with posterior vitreous detachment (PVD, to determine the prevalence of retinal tears in PVD patients, and to find predictors for retinal tears in this patient group. Methods: Retrospective analysis of medical records on patients diagnosed with PVD, retinal tears, or vitreous hemorrhage at the Department of Ophthalmology at Sahlgrenska University Hospital, a tertiary eye center. Results: Between February and July 2009, 365 patients consulted the Department of Ophthalmology for PVD-related symptoms. The incidence of retinal tears was 14.5% (n=53 and that of vitreous and/or retinal hemorrhage was 22.7% (n=83. For analysis of possible predictors for complications to PVD, patients diagnosed with retinal tears or vitreous hemorrhage between May and July 2009 were also included in the study, resulting in a total of 426 patients. Predictors of a retinal tear were symptoms of visual impairment (P=0.024, the presence of vitreous or retinal hemorrhage at examination (P<0.001, and a duration of symptoms for <24 hours (P=0.004. Symptoms of flashes did not constitute an extra risk of retinal tears (P=0.135. Subsequent retinal pathology (follow-up time 4.5 years, including vitreous detachment/hemorrhage or retinal tears/detachment, occurred more often in patients presenting with a retinal tear. For patients with a retinal tear, the relative risk of having a retinal detachment in the same eye during the follow-up time was 17.7 when compared to patients without a retinal tear (risk ratio 17.7, 95% confidence interval 2.2–145. Conclusion: Patients seeking care on the first day have a

Vortex Generators in a Streamline-Traced, External-Compression Supersonic Inlet

Science.gov (United States)

Baydar, Ezgihan; Lu, Frank K.; Slater, John W.; Trefny, Charles J.

2017-01-01

Vortex generators within a streamline-traced, external-compression supersonic inlet for Mach 1.66 were investigated to determine their ability to increase total pressure recovery and reduce total pressure distortion. The vortex generators studied were rectangular vanes arranged in counter-rotating and co-rotating arrays. The vane geometric factors of interest included height, length, spacing, angle-of-incidence, and positions upstream and downstream of the inlet terminal shock. The flow through the inlet was simulated numerically through the solution of the steady-state, Reynolds-averaged Navier-Stokes equations on multi-block, structured grids using the Wind-US flow solver. The vanes were simulated using a vortex generator model. The inlet performance was characterized by the inlet total pressure recovery and the radial and circumferential total pressure distortion indices at the engine face. Design of experiments and statistical analysis methods were applied to quantify the effect of the geometric factors of the vanes and search for optimal vane arrays. Co-rotating vane arrays with negative angles-of-incidence positioned on the supersonic diffuser were effective in sweeping low-momentum flow from the top toward the sides of the subsonic diffuser. This distributed the low-momentum flow more evenly about the circumference of the subsonic diffuser and reduced distortion. Co-rotating vane arrays with negative angles-of-incidence or counter-rotating vane arrays positioned downstream of the terminal shock were effective in mixing higher-momentum flow with lower-momentum flow to increase recovery and decrease distortion. A strategy of combining a co-rotating vane array on the supersonic diffuser with a counter-rotating vane array on the subsonic diffuser was effective in increasing recovery and reducing distortion.

Empirical method to calculate Clinch River Breeder Reactor (CRBR) inlet plenum transient temperatures

International Nuclear Information System (INIS)

Howarth, W.L.

1976-01-01

Sodium flow enters the CRBR inlet plenum via three loops or inlets. An empirical equation was developed to calculate transient temperatures in the CRBR inlet plenum from known loop flows and temperatures. The constants in the empirical equation were derived from 1/4 scale Inlet Plenum Model tests using water as the test fluid. The sodium temperature distribution was simulated by an electrolyte. Step electrolyte transients at 100 percent model flow were used to calculate the equation constants. Step electrolyte runs at 50 percent and 10 percent flow confirmed that the constants were independent of flow. Also, a transient was tested which varied simultaneously flow rate and electrolyte. Agreement of the test results with the empirical equation results was good which verifies the empirical equation

Evaluation of inlet sampling integrity on NSF/NCAR airborne platforms

Science.gov (United States)

Campos, T. L.; Stith, J. L.; Stephens, B. B.; Romashkin, P.

2017-12-01

An inlet test project was conducted during IDEAS-IV-GV (2013), to evaluate the sampling integrity of two inlet designs. Use of a single CO2 sensor provided a high precision detector and a large difference in the mean cabin and external concentrations (500-700 ppmv in the cabin). The original HIAPER Modular InLet (HIMIL) is comprised of a tapered flow straightening flow through `cigar' mounted to a strut. The cigar center sampling line sits 12" from the fuselage skin. An o-ring seals the feedthrough plate coupling sampling lines from the strut into the cigar. However, there is no seal to prevent air inside the strut from seeping out around the cigar body. A pressure-equalizing drain hole in the strut access panel; it was positioned at an approximate distance of 4" from the fuselage to ensure that air from any source that drained out of the strut was confined to a low release point. A second aft-facing inlet design was also evaluated. The sampling center line was moved farther from the fuselage at a height of 16". A similar approach was also applied to sampling locations on the C-130 in 2015. The results of these tests and recommendations for best practices will be presented.

Study on the design of inlet and exhaust system of a stationary internal combustion engine

International Nuclear Information System (INIS)

Kesgin, Ugur

2005-01-01

The design and operational variables of inlet and exhaust systems are decisive to determine overall engine performance. The best engine overall performance can be obtained by proper design of the engine inlet and exhaust systems and by matching the correct turbocharger to the engine. This paper presents the results of investigations to design the inlet and exhaust systems of a stationary natural gas engine family. To do this, a computational model is verified in which zero dimensional phenomena within the cylinder and one dimensional phenomena in the engine inlet and exhaust systems are used. Using this engine model, the effects of the parameters of the inlet and exhaust systems on the engine performance are obtained. In particular, the following parameters are chosen: valve timing, valve diameter, valve lift profiles, diameter of the exhaust manifold, inlet and exhaust pipe lengths, and geometry of pipe junctions. Proper sizing of the inlet and exhaust pipe systems is achieved very precisely by these investigations. Also, valve timing is tuned by using the results obtained in this study. In general, a very high improvement potential for the engines studied here is presented

Dissecting the roles of ROCK isoforms in stress-induced cell detachment

OpenAIRE

Shi, Jianjian; Surma, Michelle; Zhang, Lumin; Wei, Lei

2013-01-01

The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1 ?/? and ROCK2?/? mice, we have recently reported that they play different roles in regulating doxorubicin-induced stress fiber disassembly and cell detachment: ROCK1 is involved in destabilizing the actin cytoskeleton and cell detachment, whereas ROCK2 is required for stabilizing the actin...

Thermal stratification built up in hot water tank with different inlet stratifiers

DEFF Research Database (Denmark)

Dragsted, Janne; Furbo, Simon; Dannemand, Mark

2017-01-01

Thermal stratification in a water storage tank can strongly increase the thermal performance of solar heating systems. Thermal stratification can be built up in a storage tank during charge, if the heated water enters through an inlet stratifier. Experiments with a test tank have been carried out...... in order to elucidate how well thermal stratification is established in the tank with differently designed inlet stratifiers under different controlled laboratory conditions. The investigated inlet stratifiers are from Solvis GmbH & Co KG and EyeCular Technologies ApS. The inlet stratifier from Solvis Gmb...... for Solvis GmbH & Co KG had a better performance at 4 l/min. In the intermediate charge test the stratifier from EyeCular Technologies ApS had a better performance in terms of maintaining the thermal stratification in the storage tank while charging with a relative low temperature. [All rights reserved...

Applicability of Different Hydraulic Parameters to Describe Soil Detachment in Eroding Rills

Science.gov (United States)

Wirtz, Stefan; Seeger, Manuel; Zell, Andreas; Wagner, Christian; Wagner, Jean-Frank; Ries, Johannes B.

2013-01-01

This study presents the comparison of experimental results with assumptions used in numerical models. The aim of the field experiments is to test the linear relationship between different hydraulic parameters and soil detachment. For example correlations between shear stress, unit length shear force, stream power, unit stream power and effective stream power and the detachment rate does not reveal a single parameter which consistently displays the best correlation. More importantly, the best fit does not only vary from one experiment to another, but even between distinct measurement points. Different processes in rill erosion are responsible for the changing correlations. However, not all these procedures are considered in soil erosion models. Hence, hydraulic parameters alone are not sufficient to predict detachment rates. They predict the fluvial incising in the rill's bottom, but the main sediment sources are not considered sufficiently in its equations. The results of this study show that there is still a lack of understanding of the physical processes underlying soil erosion. Exerted forces, soil stability and its expression, the abstraction of the detachment and transport processes in shallow flowing water remain still subject of unclear description and dependence. PMID:23717669

Biochar-amended filter socks reduce herbicide losses via tile line surface inlets

Science.gov (United States)

Standing water in depressions and behind terraces in fields with subsurface drainage systems can result in reduced crop yields. This concern can be partially alleviated by installing surface inlets that reduce the duration of ponding. Unfortunately, these inlets provide an open conduit for surface w...

The fellow eye in patients with unilateral retinal detachment: findings and prophylactic treatment.

Science.gov (United States)

Laatikainen, L

1985-10-01

During a 4-year period, 1978-1981, 312 patients were operated on for unilateral rhegmatogenous detachment of the retina. Of the fellow eyes, 11% showed moderate (VA 0.15-0.4) and 5% severe (VA less than or equal to 0.1) visual impairment. Of the fellow eyes 49% were myopic (- 1.0 D. or more), and aphakia was present in 14%. Details of the peripheral fundus were adequately recordable for 260 fellow eyes. Degenerations considered to predispose to retinal detachment were found in 98 eyes (38%): lattice degeneration in 54 (21%), granular tuft in 17 (7%), retinal tear(s) in 12 (5%), and retinoschisis in 15 (6%). Prophylactic treatment of predisposing degenerations was performed in 91 of the 98 eyes using cryo- or photocoagulation (argon laser). No intra- or permanent post-operative complications were noticed. One of the treated fellow eyes (1.1%) detached 10 months after prophylactic treatment due to new tears. In the untreated group, 6 of the 221 eyes detached (2.7%). The difference was not statistically significant, but the groups were not comparable because 93% of the eyes showing predisposing degenerations were treated. None of the eyes treated for retinal breaks or lattice degeneration has detached. In these cases prophylactic treatment of the fellow eye is recommended. In most eyes cryocoagulation seems to be preferable to photocoagulation.

Growth and detachment of single hydrogen bubbles in a magnetohydrodynamic shear flow

Science.gov (United States)

Baczyzmalski, Dominik; Karnbach, Franziska; Mutschke, Gerd; Yang, Xuegeng; Eckert, Kerstin; Uhlemann, Margitta; Cierpka, Christian

2017-09-01

This study investigates the effect of a magnetohydrodynamic (MHD) shear flow on the growth and detachment of single sub-millimeter-sized hydrogen gas bubbles. These bubbles were electrolytically generated at a horizontal Pt microelectrode (100 μ m in diameter) in an acidic environment (1 M H2SO4 ). The inherent electric field was superimposed by a homogeneous electrode-parallel magnetic field of up to 700 mT to generate Lorentz forces in the electrolyte, which drive the MHD flow. The growth and motion of the hydrogen bubble was analyzed by microscopic high-speed imaging and measurements of the electric current, while particle tracking velocimetry (μ PTV ) and particle image velocimetry (μ PIV ) were applied to measure the surrounding electrolyte flow. In addition, numerical flow simulations were performed based on the experimental conditions. The results show a significant reduction of the bubble growth time and detachment diameter with increasing magnetic induction, which is known to improve the efficiency of water electrolysis. In order to gain further insight into the bubble detachment mechanism, an analysis of the forces acting on the bubble was performed. The strong MHD-induced drag force causes the bubble to slowly slide away from the center of the microelectrode before its detachment. This motion increases the active electrode area and enhances the bubble growth rate. The results further indicate that at large current densities the coalescence of tiny bubbles formed at the foot of the main bubble might play an important role for the bubble detachment. Moreover, the occurrence of Marangoni stresses at the gas-liquid interface is discussed.

Adaptive timing of detachment in a tick parasitizing hole-nesting birds.

Science.gov (United States)

White, J; Heylen, D J A; Matthysen, E

2012-02-01

In non-permanent parasites with low intrinsic mobility such as ticks, dispersal is highly dependent on host movements as well as the timing of separation from the hosts. Optimal detachment behaviour is all the more crucial in nidicolous ticks as the risk of detaching in non-suitable habitat is high. In this study, we experimentally investigated the detachment behaviour of Ixodes arboricola, a nidicolous tick that primarily infests birds roosting in tree-holes. We infested great tits with I. arboricola larvae or nymphs, and submitted the birds to 2 experimental treatments, a control treatment in which birds had normal access to nest boxes and an experimental treatment, in which the birds were prevented access to their nest boxes for varying lengths of time. In the control group, most ticks detached within 5 days, whereas in the experimental group, ticks remained on the bird for as long as the bird was prevented access (up to 14 days). This prolonged attachment caused a decrease in survival and engorgement weight in nymphs, but not in larvae. The capacity of I. arboricola larvae to extend the duration of attachment in non-suitable environments with no apparent costs, may be an adaptation to unpredictable use of cavities by roosting hosts during winter, and at the same time may facilitate dispersal of the larval instars.

Zonal Detached-Eddy Simulation of Turbulent Unsteady Flow over Iced Airfoils

KAUST Repository

Zhang, Yue

2015-07-23

This paper presentsamultiscale finite-element formulation for the second modeofzonal detached-eddy simulation. The multiscale formulation corrects the lack of stability of the standard Galerkin formulation by incorporating the effect of unresolved scales to the grid (resolved) scales. The stabilization terms arise naturally and are free of userdefined stability parameters. Validation of the method is accomplished via the turbulent flow over tandem cylinders. The boundary-layer separation, free shear-layer rollup, vortex shedding from the upstream cylinder, and interaction with the downstream cylinder are well reproduced. Good agreement with experimental measurements gives credence to the accuracy of zonal detached-eddy simulation in modeling turbulent separated flows. A comprehensive study is then conducted on the performance degradation of ice-contaminated airfoils. NACA 23012 airfoil with a spanwise ice ridge and Gates Learjet Corporation-305 airfoil with a leading-edge horn-shape glaze ice are selected for investigation. Appropriate spanwise domain size and sufficient grid density are determined to enhance the reliability of the simulations. A comparison of lift coefficient and flowfield variables demonstrates the added advantage that the zonal detached-eddy simulation model brings to the Spalart-Allmaras turbulence model. Spectral analysis and instantaneous visualization of turbulent structures are also highlighted via zonal detached-eddy simulation. Copyright © 2015 by the CFD Lab of McGill University. Published by the American Institute of Aeronautics and Astronautics, Inc.

Being mindful at work and at home : Buffering effects in the stressor–detachment model

NARCIS (Netherlands)

Haun, Verena C.; Nübold, Annika; Bauer, Anna G.

In this daily diary study, we examined the moderating role of employee domain‐specific mindfulness within the stressor–detachment model (Sonnentag & Fritz, 2015, Journal of Organizational Behavior, 36, 72). According to the stressor–detachment model, emotional and quantitative demands should be

Miniature piezo electric vacuum inlet valve

Science.gov (United States)

Keville, Robert F.; Dietrich, Daniel D.

1998-03-24

A miniature piezo electric vacuum inlet valve having a fast pulse rate and is battery operated with variable flow capability. The low power (piezo electric valves which require preloading of the crystal drive mechanism and 120 Vac, thus the valve of the present invention is smaller by a factor of three.

Mercury in Sediment, Water, and Biota of Sinclair Inlet, Puget Sound, Washington, 1989-2007

Science.gov (United States)

Paulson, Anthony J.; Keys, Morgan E.; Scholting, Kelly L.

2010-01-01

Historical records of mercury contamination in dated sediment cores from Sinclair Inlet are coincidental with activities at the U.S. Navy Puget Sound Naval Shipyard; peak total mercury concentrations occurred around World War II. After World War II, better metallurgical management practices and environmental regulations reduced mercury contamination, but total mercury concentrations in surface sediment of Sinclair Inlet have decreased slowly because of the low rate of sedimentation relative to the vertical mixing within sediment. The slopes of linear regressions between the total mercury and total organic carbon concentrations of sediment offshore of Puget Sound urban areas was the best indicator of general mercury contamination above pre-industrial levels. Prior to the 2000-01 remediation, this indicator placed Sinclair Inlet in the tier of estuaries with the highest level of mercury contamination, along with Bellingham Bay in northern Puget Sound and Elliott Bay near Seattle. This indicator also suggests that the 2000/2001 remediation dredging had significant positive effect on Sinclair Inlet as a whole. In 2007, about 80 percent of the area of the Bremerton naval complex had sediment total mercury concentrations within about 0.5 milligrams per kilogram of the Sinclair Inlet regression. Three areas adjacent to the waterfront of the Bremerton naval complex have total mercury concentrations above this range and indicate a possible terrestrial source from waterfront areas of Bremerton naval complex. Total mercury concentrations in unfiltered Sinclair Inlet marine waters are about three times higher than those of central Puget Sound, but the small numbers of samples and complex physical and geochemical processes make it difficult to interpret the geographical distribution of mercury in marine waters from Sinclair Inlet. Total mercury concentrations in various biota species were compared among geographical locations and included data of composite samples, individual

Analytical and Experimental Investigation of Inlet-engine Matching for Turbojet-powered Aircraft at Mach Numbers up to 2.0

Science.gov (United States)

Esenwein, Fred T; Schueller, Carl F

1952-01-01

An analysis of inlet-turbojet-engine matching for a range of Mach numbers up to 2.0 indicates large performance penalties when fixed-geometry inlets are used. Use of variable-geometry inlets, however, nearly eliminates th The analysis was confirmed experimentally by investigating at Mach numbers of 0, 0.63, and 1.5 to 2.0 two single oblique-shock-type inlets of different compression-ramp angles, which simulated a variable-geometry configuration. The experimental investigation indicated that total-pressure recoveries comparable withose attainable with well designed nose inlets were obtained with the side inlets when all the boundary layer ahead of the inlets was removed. Serious drag penalties resulted at a Mach number of 2.0 from the use of blunt-cowl leading edges. However, sharp-lip inlets produced large losses in thrust for the take-off condition. These thrust penalties which are associated with the the low-speed operation of the sharp-lip inlet designs can probably be avoided without impairing the supersonic performance of the inlet by the use of auxiliary inlets or blow-in doors.

Bathymetric Signatures of Oceanic Detachment Faulting and Potential Ultramafic Lithologies at Outcrop or in the Shallow Subseafloor

Science.gov (United States)

Cann, J. R.; Smith, D. K.; Escartin, J.; Schouten, H.

2008-12-01

For ten years, domal bathymetric features capped by corrugated and striated surfaces have been recognized as exposures of oceanic detachment faults, and hence potentially as exposures of plutonic rocks from lower crust or upper mantle. Associated with these domes are other bathymetric features that indicate the presence of detachment faulting. Taken together these bathymetric signatures allow the mapping of large areas of detachment faulting at slow and intermediate spreading ridges, both at the axis and away from it. These features are: 1. Smooth elevated domes corrugated parallel to the spreading direction, typically 10-30 km wide parallel to the axis; 2. Linear ridges with outward-facing slopes steeper than 20°, running parallel to the spreading axis, typically 10-30 km long; 3. Deep basins with steep sides and relatively flat floors, typically 10-20 km long parallel to the spreading axis and 5-10 km wide. This characteristic bathymetric association arises from the rolling over of long-lived detachment faults as they spread away from the axis. The faults dip steeply close to their origin at a few kilometers depth near the spreading axis, and rotate to shallow dips as they continue to evolve, with associated footwall flexure and rotation of rider blocks carried on the fault surface. The outward slopes of the linear ridges can be shown to be rotated volcanic seafloor transported from the median valley floor. The basins may be formed by the footwall flexure, and may be exposures of the detachment surface. Critical in this analysis is that the corrugated domes are not the only sites of detachment faulting, but are the places where higher parts of much more extensive detachment faults happen to be exposed. The fault plane rises and falls along axis, and in some places is covered by rider blocks, while in others it is exposed at the sea floor. We use this association to search for evidence for detachment faulting in existing surveys, identifying for example an area

Electron detachment of the hydrogen-bonded amino acid side-chain guanine complexes

Science.gov (United States)

Wang, Jing; Gu, Jiande; Leszczynski, Jerzy

2007-07-01

The photoelectron spectra of the hydrogen-bonded amino acid side-chain-guanine complexes has been studied at the partial third order (P3) self-energy approximation of the electron propagator theory. The correlation between the vertical electron detachment energy and the charge distributions on the guanine moiety reveals that the vertical electron detachment energy (VDE) increases as the positive charge distribution on the guanine increases. The low VDE values determined for the negatively charged complexes of the guanine-side-chain-group of Asp/Glu suggest that the influence of the H-bonded anionic groups on the VDE of guanine could be more important than that of the anionic backbone structure. The even lower vertical electron detachment energy for guanine is thus can be expected in the H-bonded protein-DNA systems.

Photorefractive keratectomy for visual rehabilitation of anisometropia induced by retinal detachment surgery.

Science.gov (United States)

Bilgihan, K; Ozdek, S C; Gürelik, G; Adigüzel, U; Onol, M; Hasanreisoglu, B

2000-01-01

To evaluate the efficacy of unilateral photorefractive keratectomy to correct anisometropia induced by retinal detachment surgery. Photorefractive keratectomy was performed in 10 eyes of 10 patients with anisometropia induced by previous retinal detachment surgery. The Aesculap Meditec MEL 60 excimer laser was used. Preoperative mean spherical equivalent refraction was -5.20 D. Mean postoperative spherical equivalent refraction was -0.25 D after a mean follow-up of 12.9 months. Mean preoperative spherical equivalent refraction difference between two eyes of 4.87 D was decreased to a mean 0.60 D postoperatively (t-test, P < .0001). All patients were free of anisometropic symptoms after laser surgery. Unilateral photorefractive keratectomy seems to be an effective method to correct anisometropia induced by conventional retinal detachment surgery, especially for patients with spectacle and contact lens intolerance.

Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment.

Science.gov (United States)

Wilkinson, Charles P

2014-09-05

Asymptomatic retinal breaks and lattice degeneration are visible lesions that are risk factors for later retinal detachment. Retinal detachments occur when fluid in the vitreous cavity passes through tears or holes in the retina and separates the retina from the underlying retinal pigment epithelium. Creation of an adhesion surrounding retinal breaks and lattice degeneration, with laser photocoagulation or cryotherapy, has been recommended as an effective means of preventing retinal detachment. This therapy is of value in the management of retinal tears associated with the symptoms of flashes and floaters and persistent vitreous traction upon the retina in the region of the retinal break, because such symptomatic retinal tears are associated with a high rate of progression to retinal detachment. Retinal tears and holes unassociated with acute symptoms and lattice degeneration are significantly less likely to be the sites of retinal breaks that are responsible for later retinal detachment. Nevertheless, treatment of these lesions frequently is recommended, in spite of the fact that the effectiveness of this therapy is unproven. The objective of this review was to assess the effectiveness and safety of techniques used to treat asymptomatic retinal breaks and lattice degeneration for the prevention of retinal detachment. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2014, Issue 2), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to February 2014), EMBASE (January 1980 to February 2014), PubMed (January 1948 to February 2014), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials

Viscous flow considerations in the design of the Busemann hypersonic air inlet

International Nuclear Information System (INIS)

Walsh, P.C.; Tahir, R.B.; Molder, S.

2002-01-01

A cost effective means of traveling to a low earth orbit is using an aircraft that relies on air-breathing engine technology for most of its trajectory while in the atmosphere. The scramjets that would be used to provide propulsion require inlet air diffusion with minimal total pressure losses to maintain efficiency. The Busemann inlet was designed using inviscid flow assumptions specifically for such purposes. This paper presents an investigation into the effects of viscosity on inlet performance in terms of static pressure rise and internal shockwave configuration. The viscous effects within the inlet can alter the design pressure ratio as much as 50%. It was shown that a correction based on a displacement radius calculation was sufficient to restore the static pressure performance of the inviscid design. An improvement of 16% in total pressure losses was observed with the corrected Busemann profile. Results are compared to experimentally determined surface pressure values. (author)

Adolescent-Peer Relationships, Separation and Detachment from Parents, and Internalizing and Externalizing Behaviors: Linkages and Interactions

Science.gov (United States)

Jager, Justin; Yuen, Cynthia X.; Putnick, Diane L.; Hendricks, Charlene; Bornstein, Marc H.

2018-01-01

Most research exploring the interplay between context and adolescent separation and detachment has focused on the family; in contrast, this investigation directs its attention outside of the family to peers. Utilizing a latent variable approach for modeling interactions and incorporating reports of behavioral adjustment from 14-year-old adolescents (N = 190) and their mothers, we examine how separation and detachment relate to adolescent peer relationships, and whether peer relationships moderate how separation and detachment relate to adolescent internalizing and externalizing behaviors. Positive peer relationships were both associated with lower detachment and sharply attenuated relations between detachment and higher adolescent internalizing and externalizing. Separation from parents was unrelated to peer relationships, and regardless of whether peer relationships were positive, separation was not related to adolescent internalizing and externalizing. We integrate these findings with those from family-focused investigations and discuss their substantive and clinical implications. PMID:29527086

Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins.

Science.gov (United States)

Takshak, Anjneya; Kunwar, Ambarish

2016-05-01

Many cellular processes are driven by collective forces generated by a team consisting of multiple molecular motor proteins. One aspect that has received less attention is the detachment rate of molecular motors under mechanical force/load. While detachment rate of kinesin motors measured under backward force increases rapidly for forces beyond stall-force; this scenario is just reversed for non-yeast dynein motors where detachment rate from microtubule decreases, exhibiting a catch-bond type behavior. It has been shown recently that yeast dynein responds anisotropically to applied load, i.e. detachment rates are different under forward and backward pulling. Here, we use computational modeling to show that these anisotropic detachment rates might help yeast dynein motors to improve their collective force generation in the absence of catch-bond behavior. We further show that the travel distance of cargos would be longer if detachment rates are anisotropic. Our results suggest that anisotropic detachment rates could be an alternative strategy for motors to improve the transport properties and force production by the team. © 2016 The Protein Society.

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death.

Directory of Open Access Journals (Sweden)

Marie-Noëlle Delyfer

Full Text Available BACKGROUND: Retinal detachment often leads to a severe and permanent loss of vision and its therapeutic management remains to this day exclusively surgical. We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment in order to identify new potential pharmacological targets that could be used in combination with surgery to further improve final outcome. METHODOLOGY/PRINCIPAL FINDINGS: Statistical analysis reveals major involvement of the immune response in the disease. Interestingly, using a novel approach relying on coordinated expression, the interindividual variation was monitored to unravel a second crucial aspect of the pathological process: the death of photoreceptor cells. Within the genes identified, the expression of the major histocompatibility complex I gene HLA-C enables diagnosis of the disease, while PKD2L1 and SLCO4A1 -which are both down-regulated- act synergistically to provide an estimate of the duration of the retinal detachment process. Our analysis thus reveals the two complementary cellular and molecular aspects linked to retinal detachment: an immune response and the degeneration of photoreceptor cells. We also reveal that the human specimens have a higher clinical value as compared to artificial models that point to IL6 and oxidative stress, not implicated in the surgical specimens studied here. CONCLUSIONS/SIGNIFICANCE: This systematic analysis confirmed the occurrence of both neurodegeneration and inflammation during retinal detachment, and further identifies precisely the modification of expression of the different genes implicated in these two phenomena. Our data henceforth give a new insight into the disease process and provide a rationale for therapeutic strategies aimed at limiting inflammation and photoreceptor damage associated with retinal detachment and, in turn, improving visual prognosis after retinal surgery.

Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.

Science.gov (United States)

Auckland, Philip; Clarke, Nicholas I; Royle, Stephen J; McAinsh, Andrew D

2017-06-05

Kinetochores mediate chromosome congression by either sliding along the lattice of spindle microtubules or forming end-on attachments to their depolymerizing plus-ends. By following the fates of individual kinetochores as they congress in live cells, we reveal that the Ska complex is required for a distinct substep of the depolymerization-coupled pulling mechanism. Ska depletion increases the frequency of naturally occurring, force-dependent P kinetochore detachment events, while being dispensable for the initial biorientation and movement of chromosomes. In unperturbed cells, these release events are followed by reattachment and successful congression, whereas in Ska-depleted cells, detached kinetochores remain in a futile reattachment/detachment cycle that prevents congression. We further find that Ska is progressively loaded onto bioriented kinetochore pairs as they congress. We thus propose a model in which kinetochores mature through Ska complex recruitment and that this is required for improved load-bearing capacity and silencing of the spindle assembly checkpoint. © 2017 Auckland et al.

Rhegmatogenous retinal detachment in an eye of retinoblastoma treated by radiation and cryocoagulation

International Nuclear Information System (INIS)

Inoue, Makoto; Tanaka, Yasuhiko; Kawai, Masataka; Nii, Seiji; Katsura, Hiroshi; Kaneko, Akihiro

1999-01-01

A 4-month-old female infant was diagnosed as bilateral retinoblastoma. The left eye was treated by enucleation and the right by radiation. The right eye received repeated thermochemotherapy, cryocoagulation and photocoagulation for recurrence. Total retinal detachment was detected after surgery for complicated cataract at the age of 2 years 9 months. Vitreous surgery led to the detection of posterior vitreous detachment and retinal breaks in the coagulated scar areas with vitreoretinal adhesion around the calcified tumor. During the following one year, the retina has been attached with no reoccurrence of the tumor. This case illustrates that rhegmatogenous retinal detachment is a possibility in retinoblastoma treated by radiation or retinal coagulations. (author)

Effects of RGD immobilization on light-induced cell sheet detachment from TiO{sub 2} nanodots films

Energy Technology Data Exchange (ETDEWEB)

Cheng, Kui; Wang, Tiantian [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); Yu, Mengliu [The Affiliated Stomatologic Hospital, Zhejiang University, Hangzhou 310003 (China); The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China); Wan, Hongping [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); Lin, Jun [The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China); Weng, Wenjian, E-mail: wengwj@zju.edu.cn [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); The Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China); Wang, Huiming, E-mail: hmwang1960@hotmail.com [The Affiliated Stomatologic Hospital, Zhejiang University, Hangzhou 310003 (China); The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China)

2016-06-01

Light-induced cell detachment is reported to be a safe and effective cell sheet harvest method. In the present study, the effects of arginine–glycine–aspartic acid (RGD) immobilization on cell growth, cell sheet construction and cell harvest through light illumination are investigated. RGD was first immobilized on TiO{sub 2} nanodots films through simple physical adsorption, and then mouse pre-osteoblastic MC3T3-E1 cells were seeded on the films. It was found that RGD immobilization promoted cell adhesion and proliferation. It was also observed that cells cultured on RGD immobilized films showed relatively high level of pan-cadherin. Cells harvested with ultraviolet illumination (365 nm) showed good viability on both RGD immobilized and unmodified TiO{sub 2} nanodot films. Single cell detachment assay showed that cells detached more quickly on RGD immobilized TiO{sub 2} nanodot films. That could be ascribed to the RGD release after UV365 illumination. The current study demonstrated that RGD immobilization could effectively improve both the cellular responses and light-induced cell harvest. - Highlights: • RGD immobilization on TiO{sub 2} nanodots film favors light-induced cell sheet detachment. • Physically adsorbed RGD detaches from the film through ultraviolet illumination. • RGD detachment promotes cells and cell sheets detachment.

Method of detaching adherent cells for flow cytometry

KAUST Repository

Kaur, Mandeep; Esau, Luke E.

2015-01-01

In one aspect, a method for detaching adherent cells can include adding a cell lifting solution to the media including a sample of adherent cells and incubating the sample of adherent cells with the cell lifting solution. No scraping or pipetting

Incidence of retinal detachment associated with atopic dermatitis in Japan: review of cases from 1992 to 2011

Directory of Open Access Journals (Sweden)

Sasoh M

2015-06-01

Full Text Available Mikio Sasoh,1,2 Hitoshi Mizutani,3 Hisashi Matsubara,1 Motoyasu Furuta,4 Yoshitsugu Matsui,1 Kei-ichi Yamanaka,3 Mineo Kondo11Department of Ophthalmology, Graduate School of Medicine, Mie University, Tsu, 2Local Independent Administrative Institution, Mie Prefectural General Medical Center, Yokkaichi, 3Department of Dermatology, Graduate School of Medicine, Mie University, Tsu, 4Japanese Red Cross Ise Hospital, Ise, Mie, JapanPurpose: The present study aims to investigate the number and characteristics of retinal detachment with atopic dermatitis (AD in these 20 years, and the number of the first visit AD outpatients in almost the same period.Methods: A retrospective review of 101 consecutive surgically treated retinal detachments with AD patients from 1992 to 2011 was conducted. Retinal detachments were divided into two groups: eyes operated on from 1992 to 2001 (former AD group, n=63 and eyes operated on from 2002 to 2011 (recent AD group, n=38. We also reviewed the records of the first visit AD outpatients from 1993 to 2011 except 1998.Results: The percentage of bilateral detachment was significantly higher in the former AD group (14/63 than that in the recent AD group (0/38 (P=0.0002. In addition, patients in the recent AD group were significantly older than those in the former AD group (P=0.0084. The annual cases with non-AD retinal detachment remained invariant for 20 years. The ratio of the retinal detachment with AD for the total retinal detachment was significantly lower in the recent (38/847 AD group than that in the former (63/796 AD group (P=0.0038. The number of the first visit AD outpatients linearly decreased in these 19 years (153 cases in 1993 and 65 cases in 2011.Conclusion: Our study indicates an apparent decrease in retinal detachment with AD in the recent 10 years, and might suggest the importance of dermatitis control for prevention of retinal detachment with AD.Keywords: atopic dermatitis, incidence, ocular

Nuclear research reactor IEA-R1 heat exchanger inlet nozzle flow - a preliminary study

International Nuclear Information System (INIS)

Angelo, Gabriel; Andrade, Delvonei Alves de; Fainer, Gerson; Angelo, Edvaldo

2009-01-01

As a computational fluid mechanics training task, a preliminary model was developed. ANSYS-CFX R code was used in order to study the flow at the inlet nozzle of the heat exchanger of the primary circuit of the nuclear research reactor IEA-R1. The geometry of the inlet nozzle is basically compounded by a cylinder and two radial rings which are welded on the shell. When doing so there is an offset between the holes through the shell and the inlet nozzle. Since it is not standardized by TEMA, the inlet nozzle was chosen for a preliminary study of the flow. Results for the proposed model are presented and discussed. (author)

Analysis of the pump-turbine S characteristics using the detached eddy simulation method

Science.gov (United States)

Sun, Hui; Xiao, Ruofu; Wang, Fujun; Xiao, Yexiang; Liu, Weichao

2015-01-01

Current research on pump-turbine units is focused on the unstable operation at off-design conditions, with the characteristic curves in generating mode being S-shaped. Unlike in the traditional water turbines, pump-turbine operation along the S-shaped curve can lead to difficulties during load rejection with unusual increases in the water pressure, which leads to machine vibrations. This paper describes both model tests and numerical simulations. A reduced scale model of a low specific speed pump-turbine was used for the performance tests, with comparisons to computational fluid dynamics(CFD) results. Predictions using the detached eddy simulation(DES) turbulence model, which is a combined Reynolds averaged Naviers-Stokes(RANS) and large eddy simulation(LES) model, are compared with the two-equation turbulence mode results. The external characteristics as well as the internal flow are for various guide vane openings to understand the unsteady flow along the so called S characteristics of a pump-turbine. Comparison of the experimental data with the CFD results for various conditions and times shows that DES model gives better agreement with experimental data than the two-equation turbulence model. For low flow conditions, the centrifugal forces and the large incident angle create large vortices between the guide vanes and the runner inlet in the runner passage, which is the main factor leading to the S-shaped characteristics. The turbulence model used here gives more accurate simulations of the internal flow characteristics of the pump-turbine and a more detailed force analysis which shows the mechanisms controlling of the S characteristics.

Effects of selected design variables on three ramp, external compression inlet performance. [boundary layer control bypasses, and mass flow rate

Science.gov (United States)

Kamman, J. H.; Hall, C. L.

1975-01-01

Two inlet performance tests and one inlet/airframe drag test were conducted in 1969 at the NASA-Ames Research Center. The basic inlet system was two-dimensional, three ramp (overhead), external compression, with variable capture area. The data from these tests were analyzed to show the effects of selected design variables on the performance of this type of inlet system. The inlet design variables investigated include inlet bleed, bypass, operating mass flow ratio, inlet geometry, and variable capture area.

Selective detachment process in column flotation froth

Energy Technology Data Exchange (ETDEWEB)

Honaker, R.Q.; Ozsever, A.V.; Parekh, B.K. [University of Kentucky, Lexington, KY (United States). Dept. of Mining Engineering

2006-05-15

The selectivity in flotation columns involving the separation of particles of varying degrees of floatability is based on differential flotation rates in the collection zone, reflux action between the froth and collection zones, and differential detachment rates in the froth zone. Using well-known theoretical models describing the separation process and experimental data, froth zone and overall flotation recovery values were quantified for particles in an anthracite coal that have a wide range of floatability potential. For highly floatable particles, froth recovery had a very minimal impact on overall recovery while the recovery of weakly floatable material was decreased substantially by reductions in froth recovery values. In addition, under carrying-capacity limiting conditions, selectivity was enhanced by the preferential detachment of the weakly floatable material. Based on this concept, highly floatable material was added directly into the froth zone when treating the anthracite coal. The enriched froth phase reduced the product ash content of the anthracite product by five absolute percentage points while maintaining a constant recovery value.

Towards an entropy-based detached-eddy simulation

Science.gov (United States)

Zhao, Rui; Yan, Chao; Li, XinLiang; Kong, WeiXuan

2013-10-01

A concept of entropy increment ratio ( s¯) is introduced for compressible turbulence simulation through a series of direct numerical simulations (DNS). s¯ represents the dissipation rate per unit mechanical energy with the benefit of independence of freestream Mach numbers. Based on this feature, we construct the shielding function f s to describe the boundary layer region and propose an entropy-based detached-eddy simulation method (SDES). This approach follows the spirit of delayed detached-eddy simulation (DDES) proposed by Spalart et al. in 2005, but it exhibits much better behavior after their performances are compared in the following flows, namely, pure attached flow with thick boundary layer (a supersonic flat-plate flow with high Reynolds number), fully separated flow (the supersonic base flow), and separated-reattached flow (the supersonic cavity-ramp flow). The Reynolds-averaged Navier-Stokes (RANS) resolved region is reliably preserved and the modeled stress depletion (MSD) phenomenon which is inherent in DES and DDES is partly alleviated. Moreover, this new hybrid strategy is simple and general, making it applicable to other models related to the boundary layer predictions.

Bilateral Asymmetric Rhegmatogenous Retinal Detachment in a Patient with Stickler Syndrome

Directory of Open Access Journals (Sweden)

Caner Öztürk

2018-04-01

Full Text Available Here we present the long-term anatomical and visual outcomes of bilateral asymmetric rhegmatogenous retinal detachment repair in a patient with Stickler syndrome. A 17-year-old girl presented with decreased visual acuity in both eyes for more than one year. Her best-corrected visual acuity (BCVA was 0.1 in the right eye and 0.05 in the left eye. Slit-lamp anterior segment examination revealed subcapsular cataract in both eyes. Fundus examination showed bilateral rhegmatogenous retinal detachment, chronic retinal detachment accompanied by multiple retinal holes, tears and membranous fibrillary vitreous in the peripheral retina. Grade C2 proliferative vitreoretinopathy was observed in the left eye. Scleral buckling surgery was performed initially for both eyes. After the primary surgical procedure, retinal reattachment was achieved in the right eye and the left eye underwent phacoemulsification, intraocular lens implantation, pars plana vitrectomy (PPV, and silicone oil injection. After these surgical procedures retinal reattachment was achieved in the left eye. Silicone oil removal was performed six months after PPV surgery. After surgical treatment, BCVA was 0.6 in the right eye at the end of the 3.5-year follow-up period. After silicone oil removal, BCVA reached 0.2 in the left eye after 36 months of follow-up and retinal reattachment was achieved in both eyes. Scleral buckling surgery and PPV are effective and confidential methods for the treatment of chronic retinal detachment cases in Stickler syndrome.

Inlet for fuel assembly having finger control rods

International Nuclear Information System (INIS)

Berglund, A.; Suvanto, A.; Tornblom, L.

1975-01-01

A nuclear reactor with vertically arranged fuel assemblies positioned on supporting members and with control rods displaceably arranged in guide tubes between the fuel rods inside the fuel assemblies is described. The supporting plate is provided with a transverse end piece with throttling means for the liquid flow which passes from below up through the supporting member and past the fuel rods in the fuel assembly. The inlets for the guide tubes for the control rods are located below the end piece and the throttling means. In this way a higher pressure prevails at the inlet to the guide tubes than above the end piece, so that a stronger flow of coolant is produced through guide tubes than through the fuel assembly. (U.S.)

Digital integrated control of a Mach 2.5 mixed-compression supersonic inlet and an augmented mixed-flow turbofan engine

Science.gov (United States)

Batterton, P. G.; Arpasi, D. J.; Baumbick, R. J.

1974-01-01

A digitally implemented integrated inlet-engine control system was designed and tested on a mixed-compression, axisymmetric, Mach 2.5, supersonic inlet with 45 percent internal supersonic area contraction and a TF30-P-3 augmented turbofan engine. The control matched engine airflow to available inlet airflow. By monitoring inlet terminal shock position and over-board bypass door command, the control adjusted engine speed so that in steady state, the shock would be at the desired location and the overboard bypass doors would be closed. During engine-induced transients, such as augmentor light-off and cutoff, the inlet operating point was momentarily changed to a more supercritical point to minimize unstarts. The digital control also provided automatic inlet restart. A variable inlet throat bleed control, based on throat Mach number, provided additional inlet stability margin.

Identifying subsurface detachment defects by acoustic tracing

Czech Academy of Sciences Publication Activity Database

Sklodowski, R.; Drdácký, Miloš; Sklodowski, M.

2013-01-01

Roč. 56, June (2013), s. 56-64 ISSN 0963-8695 R&D Projects: GA ČR(CZ) GBP105/12/G059 Institutional support: RVO:68378297 Keywords : acoustic excitation * plaster detachment defects * frequency response * inspection systems * signal processing Subject RIV: JN - Civil Engineering Impact factor: 1.717, year: 2013 http://www.sciencedirect.com/science/article/pii/S0963869513000303

Three-dimensional Improved Delayed Detached Eddy Simulation of a two-bladed vertical axis wind turbine

International Nuclear Information System (INIS)

Lei, Hang; Zhou, Dai; Bao, Yan; Li, Ye; Han, Zhaolong

2017-01-01

Highlights: • The Improved Delayed Detached Eddy Simulation and polyhedral mesh are utilized. • Power coefficient and wake velocity are compared between experiments and simulations. • Improved Delayed Detached Eddy Simulation shows more vortices under dynamic stall. • Different scales of flow separations are distinguished by these two models. - Abstract: The aerodynamic performance of a two-bladed vertical axis wind turbine is investigated using the turbulence model of the Improved Delayed Detached Eddy Simulation and the polyhedral mesh. The sliding mesh technique is used to simulate the rotation of the rotor. Meanwhile, the results obtained by the shear stress transport k-ω model are presented as contrast. Then, the simulated power coefficients at different tip speed ratios and the wake velocity are validated by comparison with the experimental data from available literature. It is shown that the power coefficients and wake velocity predicted by the Improved Delayed Detached Eddy Simulation are closer to the experimental data than those by the shear stress transport k-ω model. The pressure distributions predicted by the two turbulence models show different degrees of discrepancies in different scales of flow separation. By comparing the vorticity magnitude graphs, the Improved Delayed Detached Eddy Simulation is found to be able to capture more exquisite vortices after the flow separations. Limited by its inherent ability, the shear stress transport k-ω model predicts vortices that are less realistic than those of Improved Delayed Detached Eddy Simulation. Hence, it may cause some errors in predicting the pressure distributions, especially when the blades suffer dynamic stall. It is demonstrated that the Improved Delayed Detached Eddy Simulation is regarded as a reliable model to analyze the aerodynamic performance of vertical axis wine turbines.

Erosion/redeposition analysis : status of modeling and code validation for semi-detached tokamak edge plasmas

International Nuclear Information System (INIS)

Brooks, J. N.

1999-01-01

We are analyzing erosion and tritium codeposition for ITER, DIII-D, and other devices with a focus on carbon divertor and metallic wall sputtering, for detached and semi-detached edge plasmas. Carbon chemical-sputtering hydrocarbon-transport is computed in detail using upgraded models for sputtering yields, species, and atomic and molecular processes. For the DIII-D analysis this includes proton impact and dissociative recombination for the full methane and higher hydrocarbon chains. Several mixed material (Si-C doping and Be/C) effects on erosion are examined. A semi-detached reactor plasma regime yields peak net wall erosion rates of ∼1.0 (Be), ∼0.3 (Fe), and ∼0.01 (W) cm/burn-yr, and ∼50 cm/burn-yr for a carbon divertor. Net carbon erosion is dominated by chemical sputtering in the ∼1-3 eV detached plasma zone. Tritium codeposition in divertor-sputtered redeposited carbon is high (∼10-20 g-T/1000 s ). Silicon and beryllium mixing tends to reduce carbon erosion. Initial hydrocarbon transport calculations for the DIII-D DiMES-73 detached plasma experiment show a broad spectrum of redeposited molecules with ∼90% redeposition fraction

Automatic efficiency optimization of an axial compressor with adjustable inlet guide vanes

Science.gov (United States)

Li, Jichao; Lin, Feng; Nie, Chaoqun; Chen, Jingyi

2012-04-01

The inlet attack angle of rotor blade reasonably can be adjusted with the change of the stagger angle of inlet guide vane (IGV); so the efficiency of each condition will be affected. For the purpose to improve the efficiency, the DSP (Digital Signal Processor) controller is designed to adjust the stagger angle of IGV automatically in order to optimize the efficiency at any operating condition. The A/D signal collection includes inlet static pressure, outlet static pressure, outlet total pressure, rotor speed and torque signal, the efficiency can be calculated in the DSP, and the angle signal for the stepping motor which control the IGV will be sent out from the D/A. Experimental investigations are performed in a three-stage, low-speed axial compressor with variable inlet guide vanes. It is demonstrated that the DSP designed can well adjust the stagger angle of IGV online, the efficiency under different conditions can be optimized. This establishment of DSP online adjustment scheme may provide a practical solution for improving performance of multi-stage axial flow compressor when its operating condition is varied.

Large Eddy Simulation and the effect of the turbulent inlet conditions in the mixing Tee

International Nuclear Information System (INIS)

Ndombo, Jean-Marc; Howard, Richard J.A.

2011-01-01

Highlights: → LES of Tee junctions can easily reproduce the bulk flow. → The presence or absence of a turbulent inlet condition has an affect on the wall heat transfer. → The maximum heat transfer moves 1 cm and reduces by 10% when a turbulent inlet is used. - Abstract: Thermal fatigue in Pressurized Water Reactor plants has been found to be very acute in some hot/cold Tee junction mixing zones. Large Eddy Simulation (LES) can be used to capture the unsteadiness which is responsible for the large mechanical stresses associated with thermal fatigue. Here one LES subgrid model is studied, namely the Dynamic Smagorinsky model. This paper has two goals. The first is to demonstrate some results obtained using the EDF R and D Code Saturne applied to the Vattenfall Tee junction benchmark (version 2006) and the second is to look at the effect of including synthetic turbulence at the Tee junction pipe inlets. The last goal is the main topic of this paper. The Synthetic Eddy Method is used to create the turbulent inlet conditions and is applied to two kinds of grids. One contains six million cells and the other ten million. The addition of turbulence at the inlet does not seem to have much effect on the bulk flow and all computations are in good agreement with the experimental data. However, the inlet turbulence does have an effect on the near wall flow. All cases show that the wall temperature fluctuation and the wall temperature/velocity correlation are not the same when a turbulent inlet condition is used. Inclusion of the turbulent inlet condition moves the downstream location of the maximum temperature/velocity correlation by 1 cm and reduces its magnitude by 10%. This result is very important because the temperature/velocity correlation is closely related to the turbulent heat transfer in the flow, which is in turn responsible for the mechanical stresses on the structure. Finally we have studied in detail the influence of the turbulent inlet condition just

Development of a solenoid actuated planar valveless micropump with single and multiple inlet-outlet arrangements

Science.gov (United States)

Kumar, N.; George, D.; Sajeesh, P.; Manivannan, P. V.; Sen, A. K.

2016-07-01

We report a planar solenoid actuated valveless micropump with multiple inlet-outlet configurations. The self-priming characteristics of the multiple inlet-multiple outlet micropump are studied. The filling dynamics of the micropump chamber during start-up and the effects of fluid viscosity, voltage and frequency on the dynamics are investigated. Numerical simulations for multiple inlet-multiple outlet micropumps are carried out using fluid structure algorithm. With DI water and at 5.0 Vp-p, 20 Hz frequency, the two inlet-two outlet micropump provides a maximum flow rate of 336 μl min-1 and maximum back pressure of 441 Pa. Performance characteristics of the two inlet-two outlet micropump are studied for aqueous fluids of different viscosity. Transport of biological cell lines and diluted blood samples are demonstrated; the flow rate-frequency characteristics are studied. Viability of cells during pumping with multiple inlet multiple outlet configuration is also studied in this work, which shows 100% of cells are viable. Application of the proposed micropump for simultaneous pumping, mixing and distribution of fluids is demonstrated. The proposed integrated, standalone and portable micropump is suitable for drug delivery, lab-on-chip and micro-total-analysis applications.

Work stressors and partner social undermining: Comparing negative affect and psychological detachment as mechanisms.

Science.gov (United States)

Meier, Laurenz L; Cho, Eunae

2018-05-14

With the mounting evidence that employees' work experiences spill over into the family domain and cross over to family members, it is important to understand the underlying mechanism through which work experiences affect the family domain and what factors may alleviate the adverse impact of work stress. Expanding previous research that mainly focused on the affect-based mechanism (negative affect), the present research investigated a resource-based mechanism (psychological detachment from work) in the relationship linking two work stressors (high workload and workplace incivility) with social undermining toward the partner at home. We also explored the relative strength of the mediating effects of the two mechanisms. In addition, we tested whether relationship satisfaction moderates the proposed effect of detachment on partner undermining. We tested these research questions using two studies with differing designs: a five-wave longitudinal study (N = 470) and a multisource study (N = 131). The results suggest that stressful work experiences affect the family domain via lack of detachment as well as negative affect, that the two pathways have comparable strength, and that high relationship satisfaction mitigates the negative effect of lack of detachment on partner undermining. In sum, this research extends the spillover-crossover model by establishing that poor psychological detachment from work during leisure time is an additional mechanism that links work and family. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

The effect of inlet conditions on lean premixed gas turbine combustor performance

Science.gov (United States)

Vilayanur, Suresh Ravi

The combustion community is today faced with the goal to reduce NOx at high efficiencies. This requirement has directed attention to the manner by which air and fuel are treated prior to and at the combustor inlet. This dissertation is directed to establishing the role of combustor inlet conditions on combustor performance, and to deriving an understanding of the relationship between inlet conditions and combustion performance. To investigate the complex effect of inlet parameters on combustor performance, (1) a test facility was designed and constructed, (2) hardware was designed and fabricated, (3) a statistically based technique was designed and applied, and (4) detailed in-situ measurements were acquired. Atmospheric tests were performed at conditions representative of industrial combustors: 670 K inlet preheat and an equivalence ratio of 0.47, and make the study immediately relevant to the combustion community. The effects of premixing length, fuel distribution, swirl angle, swirl vane thickness and swirl solidity were investigated. The detailed in-situ measurements were performed to form the database necessary to study the responsible mechanisms. A host of conventional and advanced diagnostics were used for the investigation. In situ measurements included the mapping of the thermal and velocity fields of the combustor, obtaining species concentrations inside the combustor, and quantifying the fuel-air mixing entering the combustor. Acoustic behavior of the combustor was studied, including the application of high speed videography. The results reveal that the principal statistically significant effect on NOx production is the inlet fuel distribution, and the principal statistically significant effect on CO production is the swirl strength. Elevated levels of NOx emission result when the fuel is weighted to the centerline. Eddies shedding off the swirler hub ignite as discrete packets, and due to the elevated concentrations of fuel, reach higher temperatures

Rocket Based Combined Cycle Exchange Inlet Performance Estimation at Supersonic Speeds

Science.gov (United States)

Murzionak, Aliaksandr

A method to estimate the performance of an exchange inlet for a Rocket Based Combined Cycle engine is developed. This method is to be used for exchange inlet geometry optimization and as such should be able to predict properties that can be used in the design process within a reasonable amount of time to allow multiple configurations to be evaluated. The method is based on a curve fit of the shocks developed around the major components of the inlet using solutions for shocks around sharp cones and 2D estimations of the shocks around wedges with blunt leading edges. The total pressure drop across the estimated shocks as well as the mass flow rate through the exchange inlet are calculated. The estimations for a selected range of free-stream Mach numbers between 1.1 and 7 are compared against numerical finite volume method simulations which were performed using available commercial software (Ansys-CFX). The total pressure difference between the two methods is within 10% for the tested Mach numbers of 5 and below, while for the Mach 7 test case the difference is 30%. The mass flow rate on average differs by less than 5% for all tested cases with the maximum difference not exceeding 10%. The estimation method takes less than 3 seconds on 3.0 GHz single core processor to complete the calculations for a single flight condition as oppose to over 5 days on 8 cores at 2.4 GHz system while using 3D finite volume method simulation with 1.5 million elements mesh. This makes the estimation method suitable for the use with exchange inlet geometry optimization algorithm.

Characterizing Interferences in an NOy Thermal Dissociation Inlet

Science.gov (United States)

Womack, C.; Veres, P. R.; Brock, C. A.; Neuman, J. A.; Eilerman, S. J.; Zarzana, K. J.; Dube, W. P.; Wild, R. J.; Wooldridge, P. J.; Cohen, R. C.; Brown, S. S.

2016-12-01

Nitrogen oxides (NOx = NO and NO2) are emitted into the troposphere by various anthropogenic and natural sources, and contribute to increased levels of ambient ozone. Reactive nitrogen species (NOy), which include nitric acid, peroxy acetyl and organic nitrates, and other species, serve as reservoirs and sinks for NOx, thus influencing O3 production. Their detection is therefore critical to understanding ozone chemistry. However, accurate measurements of NOy have proven to be difficult to obtain, and measurements of total NOy sometimes do not agree with the sum of measurements of its individual components. In recent years, quartz thermal dissociation (TD) inlets have been used to thermally convert all NOy species to NO2, followed by detection by techniques such as laser induced fluorescence (LIF) or cavity ringdown spectroscopy (CRDS). Here we discuss recent work in characterizing the NOy channel of our four-channel TD-CRDS instrument. In particular, we have examined the thermal conversion efficiency of several representative NOy species under a range of experimental conditions. We find that under certain conditions, the conversion efficiency is sensitive to inlet residence time and to the concentration of other trace gases found in ambient sampling, such as ozone. We also report the thermal dissociation curves of N2O5 and ammonium nitrate aerosol, and discuss the interferences observed when ammonia and ozone are co-sampled in the inlet.

A hybrid CFD/characteristics method for fast characterization of hypersonic blunt forebody/inlet flow

Science.gov (United States)

Gao, WenZhi; Li, ZhuFei; Yang, JiMing

2015-10-01

A hybrid CFD/characteristic method (CCM) was proposed for fast design and evaluation of hypersonic inlet flow with nose bluntness, which targets the combined advantages of CFD and method of characteristics. Both the accuracy and efficiency of the developed CCM were verified reliably, and it was well demonstrated for the external surfaces design of a hypersonic forebody/inlet with nose bluntness. With the help of CCM method, effects of nose bluntness on forebody shock shapes and the flowfield qualities which dominate inlet performance were examined and analyzed on the two-dimensional and axisymmetric configurations. The results showed that blunt effects of a wedge forebody are more substantial than that of related cone cases. For a conical forebody with a properly blunted nose, a recovery of the shock front back to that of corresponding sharp nose is exhibited, accompanied with a gradually fading out of entropy layer effects. Consequently a simplification is thought to be reasonable for an axisymmetric inlet with a proper compression angle, and a blunt nose of limited radius can be idealized as a sharp nose, as the spillage and flow variations at the entrance are negligible, even though the nose scale increases to 10% cowl lip radius. Whereas for two-dimensional inlets, the blunt effects are substantial since not only the inlet capturing/starting capabilities, but also the flow uniformities are obviously degraded.

Densiron® 68 as an intraocular tamponade for complex inferior retinal detachments

Directory of Open Access Journals (Sweden)

Hussain RN

2011-05-01

Full Text Available Rumana N Hussain, Somnath BanerjeeLeicester Royal Infirmary, Leicester, UKIntroduction: Densiron® 68 is a high-density liquid used to tamponade inferior retinal detachments. We present a case series of 12 patients treated with Densiron as an intraocular tamponade agent.Methods: A retrospective analysis of 12 eyes in 12 patients was carried out. The primary endpoint was anatomic reattachment of the retina following removal of Densiron oil.Results: All patients had inferior detachments; 33% had associated proliferative vitreoretinopathy (PVR. Densiron was utilized as a primary agent in five patients (42%; the remaining patients had prior unsuccessful surgery for retinal reattachment, including pars plana vitrectomy, cryotherapy, laser, encirclement, gas (C3F8 or C2F6, or silicone oil. Eleven patients (91% had successful reattachment of the retina at 3 months following removal of Densiron; one patient had extensive PVR, total retinal detachment, preretinal macula fibrosis, and chronic hypotony, and surgical intervention was unsuccessful. Six patients (50% had raised intraocular pressure (IOP, resolving in the majority of cases following Densiron removal; two patients had long-term raised IOP requiring topical or surgical therapy. Of the six phakic patients, 50% developed significant cataract in the operated eye. Of those with successful retinal reattachment, visual outcome was variable, with 36% patients gaining two to four lines on Snellen, 27% remaining objectively the same, and 36% losing one to two lines.Conclusion: The anatomic success rate is high (91% in patients requiring Densiron tamponade for inferior retinal detachments with or without evidence of PVR either as a primary or secondary intervention. A common complication is raised IOP; however, this most often resolves following removal of the oil.Keywords: intraocular tamponade, silicone oil, retinal detachment, retinal reattachments

Unsteady supercritical/critical dual flowpath inlet flow and its control methods

Directory of Open Access Journals (Sweden)

Jun LIU

2017-12-01

Full Text Available The characteristics of unsteady flow in a dual-flowpath inlet, which was designed for a Turbine Based Combined Cycle (TBCC propulsion system, and the control methods of unsteady flow were investigated experimentally and numerically. It was characterized by large-amplitude pressure oscillations and traveling shock waves. As the inlet operated in supercritical condition, namely the terminal shock located in the throat, the shock oscillated, and the period of oscillation was about 50 ms, while the amplitude was 6 mm. The shock oscillation was caused by separation in the diffuser. This shock oscillation can be controlled by extending the length of diffuser which reduces pressure gradient along the flowpath. As the inlet operated in critical condition, namely the terminal shock located at the shoulder of the third compression ramp, the shock oscillated, and the period of oscillation was about 7.5 ms, while the amplitude was 12 mm. At this condition, the shock oscillation was caused by an incompatible backpressure in the bleed region. It can be controlled by increasing the backpressure of the bleed region. Keywords: Airbreathing hypersonic vehicle, Dual flowpath inlet, Terminal shock oscillation, Turbine based combined cycle, Unsteady flow

Cost-Utility of Evaluation for Posterior Vitreous Detachment and Prophylaxis of Retinal Detachment.

Science.gov (United States)

Yannuzzi, Nicolas A; Chang, Jonathan S; Brown, Gary C; Smiddy, William E

2018-01-01

To evaluate the costs and cost-utility of examination for posterior vitreous detachment (PVD) and treatment of associated pathology, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD). A decision analysis model of cost-utility. There were no participants. Published retrospective data on the natural course of PVD, retinal tears, and lattice degeneration were used to quantitate the visual benefits of examination and treatment. Center for Medicare and Medicaid Services data were used to calculate associated modeled costs in a hospital/facility-based and nonfacility/ambulatory surgical center (ASC)-based setting. Published standards of utility for a given level of visual acuity were used to derive costs and quality-adjusted life years (QALYs). Cost of evaluation and treatment, utility of defined health states, QALY, and cost per QALY. The modeled cost of evaluation of a patient with PVD and treatment of associated pathology in the facility/hospital (nonfacility/ASC)-based setting was $65 to $190 ($25-$71) depending on whether a single or 2-examination protocol was used. The cost per QALY saved was $255 to $638/QALY ($100-$239/QALY). Treatment of a symptomatic horseshoe tear resulted in a net cost savings of $1749 ($1314) and improved utility, whereas treatment of an asymptomatic horseshoe tear resulted in $2981/QALY ($1436/QALY). Treatment of asymptomatic lattice degeneration in an eye in which the fellow eye had a history of RD resulted in $4414/QALY ($2187/QALY). Evaluation and management of incident acute PVD (and symptomatic horseshoe tears) offer a low cost and a favorable cost-utility (low $/QALY) as a result of the minimization of the cost and morbidity associated with the development of RD, thus justifying current practice standards. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Hexuronic Acid Stereochemistry Determination in Chondroitin Sulfate Glycosaminoglycan Oligosaccharides by Electron Detachment Dissociation

Science.gov (United States)

Leach, Franklin E.; Ly, Mellisa; Laremore, Tatiana N.; Wolff, Jeremy J.; Perlow, Jacob; Linhardt, Robert J.; Amster, I. Jonathan

2012-09-01

Electron detachment dissociation (EDD) has previously provided stereo-specific product ions that allow for the assignment of the acidic C-5stereochemistry in heparan sulfate glycosaminoglycans (GAGs), but application of the same methodology to an epimer pair in the chondroitin sulfate glycoform class does not provide the same result. A series of experiments have been conducted in which glycosaminoglycan precursor ions are independently activated by electron detachment dissociation (EDD), electron induced dissociation (EID), and negative electron transfer dissociation (NETD) to assign the stereochemistry in chondroitin sulfate (CS) epimers and investigate the mechanisms for product ion formation during EDD in CS glycoforms. This approach allows for the assignment of electronic excitation products formed by EID and detachment products to radical pathways in NETD, both of which occur simultaneously during EDD. The uronic acid stereochemistry in electron detachment spectra produces intensity differences when assigned glycosidic and cross-ring cleavages are compared. The variations in the intensities of the doubly deprotonated 0,2X3 and Y3 ions have been shown to be indicative of CS-A/DS composition during the CID of binary mixtures. These ions can provide insight into the uronic acid composition of binary mixtures in EDD, but the relative abundances, although reproducible, are low compared with those in a CID spectrum acquired on an ion trap. The application of principal component analysis (PCA) presents a multivariate approach to determining the uronic acid stereochemistry spectra of these GAGs by taking advantage of the reproducible peak distributions produced by electron detachment.

Air versus gas tamponade in retinal detachment surgery

NARCIS (Netherlands)

Tan, H. Stevie; Oberstein, Sarit Y. Lesnik; Mura, Marco; Bijl, Heico M.

2013-01-01

Objective To compare the outcome of air tamponade with gas tamponade in primary vitrectomy for the treatment of rhegmatogenous retinal detachment (RRD). Methods We examined the records of 524 cases of 523 patients that underwent primary vitrectomy for RRD with air or sulphur hexafluoride 20% gas

Effects of inlet distortion on gas turbine combustion chamber exit temperature profiles

Science.gov (United States)

Maqsood, Omar Shahzada

Damage to a nozzle guide vane or blade, caused by non-uniform temperature distributions at the combustion chamber exit, is deleterious to turbine performance and can lead to expensive and time consuming overhaul and repair. A test rig was designed and constructed for the Allison 250-C20B combustion chamber to investigate the effects of inlet air distortion on the combustion chamber's exit temperature fields. The rig made use of the engine's diffuser tubes, combustion case, combustion liner, and first stage nozzle guide vane shield. Rig operating conditions simulated engine cruise conditions, matching the quasi-non-dimensional Mach number, equivalence ratio and Sauter mean diameter. The combustion chamber was tested with an even distribution of inlet air and a 4% difference in airflow at either side. An even distribution of inlet air to the combustion chamber did not create a uniform temperature profile and varying the inlet distribution of air exacerbated the profile's non-uniformity. The design of the combustion liner promoted the formation of an oval-shaped toroidal vortex inside the chamber, creating localized hot and cool sections separated by 90° that appeared in the exhaust. Uneven inlet air distributions skewed the oval vortex, increasing the temperature of the hot section nearest the side with the most mass flow rate and decreasing the temperature of the hot section on the opposite side. Keywords: Allison 250, Combustion, Dual-Entry, Exit Temperature Profile, Gas Turbine, Pattern Factor, Reverse Flow.

The impact of inlet angle and outlet angle of guide vane on pump in reversal based hydraulic turbine performance

International Nuclear Information System (INIS)

Shi, F X; Yang, J H; Wang, X H; Zhang, R H; Li, C E

2012-01-01

In this paper, in order to research the impact of inlet angle and outlet angle of guide vane on hydraulic turbine performance, a centrifugal pump in reversal is adopted as turbine. A numerical simulation method is adopted for researching outer performance and flow field of turbine. The results show: inlet angle has a crucial role to turbine, to the same flow, there is a noticeable decline for the efficiency and head of turbine with the inlet angle increases. At the best efficiency point(EFP),to a same inlet angle, when the inlet angle greater than inlet angle, velocity circulation in guide vane outlet decreases, which lead the efficiency of turbine to reduce, Contrarily, the efficiency rises. With the increase of inlet angle and outlet angle, the EFP moves to the big flow area and the uniformity of pressure distribution becomes worse. The paper indicates that the inlet angle and outlet angle have great impact on the turbine performance, and the best combination exists for the inlet angle and outlet angle of the guide vane.

Modeling detachment physics in the NSTX snowflake divertor

Energy Technology Data Exchange (ETDEWEB)

Meier, E.T., E-mail: emeier@wm.edu [Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); Soukhanovskii, V.A. [Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); Bell, R.E.; Diallo, A.; Kaita, R.; LeBlanc, B.P. [Princeton Plasma Physics Laboratory, Princeton, NJ 08540 (United States); McLean, A.G. [Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States); Podestà, M. [Princeton Plasma Physics Laboratory, Princeton, NJ 08540 (United States); Rognlien, T.D.; Scotti, F. [Lawrence Livermore National Laboratory, Livermore, CA 94551 (United States)

2015-08-15

The snowflake divertor is a proposed technique for coping with the tokamak power exhaust problem in next-step experiments and eventually reactors, where extreme power fluxes to material surfaces represent a leading technological and physics challenge. In lithium-conditioned National Spherical Torus Experiment (NSTX) discharges, application of the snowflake divertor typically induced partial outer divertor detachment and severalfold heat flux reduction. UEDGE is used to analyze and compare conventional and snowflake divertor configurations in NSTX. Matching experimental upstream profiles and divertor measurements in the snowflake requires target recycling of 0.97 vs. 0.91 in the conventional case, implying partial saturation of the lithium-based pumping mechanism. Density scans are performed to analyze the mechanisms that facilitate detachment in the snowflake, revealing that increased divertor volume provides most of the parallel heat flux reduction. Also, neutral gas power loss is magnified by the increased wetted area in the snowflake, and plays a key role in generating volumetric recombination.

Bubble growth and detachment between two close surfaces

International Nuclear Information System (INIS)

Fath, H.E.S.

1985-01-01

Nucleate boiling is an efficient heat transfer process both as a mean of achieving high heat flux at moderate surface temperature and as a mean of generating steam. The ability to predict nucleate boiling heat flux depends on many interconnected factors such as the number of active sites, the frequency of bubble emission at these sites, and the heat transfer associated with a single bubble. Therefore, the determination of the bubble shape, growth, detachment diameter, and detachment time plays an important role in understanding the boiling mechanisms and in predicting the heat transfer rates. Although much research have been carried-out for the study of free bubble dynamics, the analysis of such problem in a narrow gap-between two close and parallel surfaces (as the gaps between steam generator tubes and tube sheet) has not been attempted, so far as the author is aware. This paper represents an attempt to shed some light on this complex problem. (author)

Intellectual property rights and detached human body parts.

Science.gov (United States)

Pila, Justine

2014-01-01

This paper responds to an invitation by the editors to consider whether the intellectual property (IP) regime suggests an appropriate model for protecting interests in detached human body parts. It begins by outlining the extent of existing IP protection for body parts in Europe, and the relevant strengths and weaknesses of the patent system in that regard. It then considers two further species of IP right of less obvious relevance. The first are the statutory rights of ownership conferred by domestic UK law in respect of employee inventions, and the second are the economic and moral rights recognised by European and international law in respect of authorial works. In the argument made, both of these species of IP right may suggest more appropriate models of sui generis protection for detached human body parts than patent rights because of their capacity better to accommodate the relevant public and private interests in respect of the same.

Bedform evolution in a tidal inlet referred from wavelet analysis

DEFF Research Database (Denmark)

Fraccascia, Serena; Winter, Christian; Ernstsen, Verner Brandbyge

2011-01-01

Bedforms are common morphological features in subaqueous and aeolian environments and their characterization is commonly the first step to better understand forcing factors acting in the system. The aim of this study was to investigate the spectral characteristics of compound bedforms in a tidal...... inlet and evaluate how they changed over consecutive years, when morphology was modified and bedforms migrated. High resolution bathymetric data from the Grådyb tidal inlet channel (Danish Wadden Sea) from seven years from 2002 to 2009 (not in 2004) were analyzed. Continuous wavelet transform of bed...

Spectroscopic investigations of divertor detachment in TCV

Directory of Open Access Journals (Sweden)

K. Verhaegh

2017-08-01

The inferred magnitude of recombination is small compared to the target ion current at the time detachment (particle flux drop starts at the target. However, recombination may be having more localized effects (to a flux tube which we cannot discern at this time. Later, at the highest densities achieved, the total recombination does reach levels similar to the particle flux.

Acoustic Monitoring of Beluga Whale Interactions with Cook Inlet Tidal Energy Project

Energy Technology Data Exchange (ETDEWEB)

Worthington, Monty [ORPC Alaska, LLC, Anchorage, AK (United States)

2014-02-05

Cook Inlet, Alaska is home to some of the greatest tidal energy resources in the U.S., as well as an endangered population of beluga whales (Delphinapterus leucas). Successfully permitting and operating a tidal power project in Cook Inlet requires a biological assessment of the potential and realized effects of the physical presence and sound footprint of tidal turbines on the distribution, relative abundance, and behavior of Cook Inlet beluga whales. ORPC Alaska, working with the Project Team—LGL Alaska Research Associates, University of Alaska Anchorage, TerraSond, and Greeneridge Science—undertook the following U.S. Department of Energy (DOE) study to characterize beluga whales in Cook Inlet – Acoustic Monitoring of Beluga Whale Interactions with the Cook Inlet Tidal Energy Project (Project). ORPC Alaska, LLC, is a wholly-owned subsidiary of Ocean Renewable Power Company, LLC, (collectively, ORPC). ORPC is a global leader in the development of hydrokinetic power systems and eco-conscious projects that harness the power of ocean and river currents to create clean, predictable renewable energy. ORPC is developing a tidal energy demonstration project in Cook Inlet at East Foreland where ORPC has a Federal Energy Regulatory Commission (FERC) preliminary permit (P-13821). The Project collected baseline data to characterize pre-deployment patterns of marine mammal distribution, relative abundance, and behavior in ORPC’s proposed deployment area at East Foreland. ORPC also completed work near Fire Island where ORPC held a FERC preliminary permit (P-12679) until March 6, 2013. Passive hydroacoustic devices (previously utilized with bowhead whales in the Beaufort Sea) were adapted for study of beluga whales to determine the relative abundance of beluga whale vocalizations within the proposed deployment areas. Hydroacoustic data collected during the Project were used to characterize the ambient acoustic environment of the project site pre-deployment to inform the

Evaluation of turbine microjet engine operating parameters in conditions conducive to inlet freezing

Directory of Open Access Journals (Sweden)

Markowski Jaroslaw

2017-01-01

Full Text Available The problem of turbine microjet engine operation is related to flight conditions of unmanned aircraft. These flights are often performed at low altitudes, where, in autumn and winter conditions, the air can be characterized by high humidity and low temperature. Such operating conditions may cause freezing the turbine engine inlet. In particular, this problem may be related to microengines, which most often are not equipped with a de-icing installation. Frosting of the inlet violates the air flow conditions at the engine inlet and may cause unstable operation and even outages, which eventually may lead to a loss of aircraft’s stability and breakdown. Therefore, an attempt was made to evaluate the changes in operational parameters of the turbine microjet engine under conditions leading to the freezing of the inlet. The engine test was performed in stationary conditions and the analysis of the obtained results are presented in this article.

Septal Leaflet versus Chordal Detachment in Closure of Hard-To-Expose Ventricular Septal Defects.

Science.gov (United States)

Pourmoghadam, Kamal K; Boron, Agnieszka; Ruzmetov, Mark; Narasimhulu, Sukumar Suguna; Kube, Alicia; O'Brien, Michael C; DeCampli, William M

2018-04-04

Different techniques have been used for exposure of ventricular septal defect (VSD) margins when there is crowding of the VSD anatomy by tricuspid valve (TV) subvalvar apparatus. The aim of this study was to compare surgical outcomes, for the two techniques of TV leaflet detachment and the rarely described TV chordal detachment for hard-to-expose VSDs. Patients undergoing transatrial VSD repair were identified from our institutional database. Follow-up echocardiography and patient data were obtained from medical records. Between 1/2005-8/2016, 130 isolated conoventricular VSDs were repaired. Among these, 26patients had leaflet detachment, while 15 underwent chordal detachment, and 89 had regular VSD repair (reference group). There was no significant difference between the groups in age, weight, postoperative length-of-stay, genetic/syndromic abnormalities, time-to-extubation, and left and right ventricular systolic function. The cardiopulmonary bypass and cross-clamp time were significantly higher in leaflet detachment group, when compared with reference group (118+28vs102+32, p=0.02; and 73+20vs61+23, p=0.01, respectively). Echocardiographic follow-up were available for 87patients at a mean of 2.6years (1month-11years). Tricuspid regurgitation was rated as none or trivial in 66(76%), mild in 20(23%) and moderate in one reference group patient. There was no difference in presence of residual VSD, or degree of tricuspid regurgitation amongst the three groups. There was no reoperation for tricuspid regurgitation. Tricuspid valve leaflet and chordal detachment techniques provide equally viable and safe alternative to closure of hard-to-expose VSDs while maintaining appropriate TV function. Their use in our series did not lead to increased TV dysfunction at early-to-midterm echocardiographic assessment. Copyright © 2018. Published by Elsevier Inc.

BILATERAL SEROUS MACULAR DETACHMENT IN A PATIENT WITH NEPHROTIC SYNDROME.

Science.gov (United States)

Bilge, Ayse D; Yaylali, Sevil A; Yavuz, Sara; Simsek, İlke B

2018-01-01

The purpose of this study was to report a case of a woman with nephrotic syndrome who presented with blurred vision because of bilateral serous macular detachment. Case report and literature review. A 55-year-old woman with a history of essential hypertension, diabetes, and nephrotic syndrome was presented with blurred vision in both eyes. Her fluorescein angiography revealed dye leakage in the early and subretinal pooling in the late phases, and optical coherence tomography scans confirmed the presence of subretinal fluid in the subfovel area. In nephrotic syndrome cases especially with accompaniment of high blood pressure, fluid accumulation in the retina layer may occur. Serous macular detachment must be kept in mind when treating these patients.

Evolving trends in primary retinal detachment repair: microincisional vitrectomy and the role of OCT.

Science.gov (United States)

Williams, Patrick D; Hariprasad, Seenu M

2014-01-01

Retinal detachment repair continues to evolve toward less invasive techniques that can safely, efficiently, and consistently provide optimal outcomes. In fact, 53% of U.S. respondents to the American Society of Retinal Specialists 2013 Preferences and Trends Survey said they would perform a vitrectomy without scleral buckle to treat a retinal detachment with a superior tear, while 25% would perform pneumatic retinopexy, and 21% would use a scleral buckle with or without vitrectomy.11 Compared to in 2005, many more surgeons prefer vitrectomy-only repair, whereas fewer prefer scleral buckle. Interestingly, preferences toward pneumatic retinopexy have slightly declined, which may reflect increased confidence in vitrectomy surgery to repair a detached retina safely and efficiently as an alternative. Even complex detachments can be treated in a minimally invasive fashion with the improvements in instrumentation, trocars, and oil infusion. While trends will likely continue toward minimal invasiveness, some form of scleral buckle, vitrectomy, and pneumatic retinopexy will all persist as treatment options. OCT advancements may allow for individualized discussions of visual prognosis and surgical decision making without the need for any invasive testing.

Outcomes in bullous retinal detachment

Directory of Open Access Journals (Sweden)

Sarah P. Read

2017-06-01

Conclusions and importance: GRTs are an uncommon cause of retinal detachment. While pars plana vitrectomy with tamponade is standard in GRT management, there is variability in the use of scleral buckling and PFO in these cases. This is in contrast to retinal dialysis where scleral buckle alone can yield favorable results. Though a baseball ocular trauma is common, retinal involvement is rare compared to other sports injuries such as those occurring with tennis, soccer and golf. Sports trauma remains an important cause of retinal injury and patients should be counseled on the need for eye protection.

Effect of inlet and outlet flow conditions on natural gas parameters in supersonic separation process.

Directory of Open Access Journals (Sweden)

Yan Yang

Full Text Available A supersonic separator has been introduced to remove water vapour from natural gas. The mechanisms of the upstream and downstream influences are not well understood for various flow conditions from the wellhead and the back pipelines. We used a computational model to investigate the effect of the inlet and outlet flow conditions on the supersonic separation process. We found that the shock wave was sensitive to the inlet or back pressure compared to the inlet temperature. The shock position shifted forward with a higher inlet or back pressure. It indicated that an increasing inlet pressure declined the pressure recovery capacity. Furthermore, the shock wave moved out of the diffuser when the ratio of the back pressure to the inlet one was greater than 0.75, in which the state of the low pressure and temperature was destroyed, resulting in the re-evaporation of the condensed liquids. Natural gas would be the subsonic flows in the whole supersonic separator, if the mass flow rate was less than the design value, and it could not reach the low pressure and temperature for the condensation and separation of the water vapor. These results suggested a guidance mechanism for natural gas supersonic separation in various flow conditions.

Computational Fluid Dynamics (CFD) Simulation of Hypersonic Turbine-Based Combined-Cycle (TBCC) Inlet Mode Transition

Science.gov (United States)

Slater, John W.; Saunders, John D.

2010-01-01

Methods of computational fluid dynamics were applied to simulate the aerodynamics within the turbine flowpath of a turbine-based combined-cycle propulsion system during inlet mode transition at Mach 4. Inlet mode transition involved the rotation of a splitter cowl to close the turbine flowpath to allow the full operation of a parallel dual-mode ramjet/scramjet flowpath. Steady-state simulations were performed at splitter cowl positions of 0deg, -2deg, -4deg, and -5.7deg, at which the turbine flowpath was closed half way. The simulations satisfied one objective of providing a greater understanding of the flow during inlet mode transition. Comparisons of the simulation results with wind-tunnel test data addressed another objective of assessing the applicability of the simulation methods for simulating inlet mode transition. The simulations showed that inlet mode transition could occur in a stable manner and that accurate modeling of the interactions among the shock waves, boundary layers, and porous bleed regions was critical for evaluating the inlet static and total pressures, bleed flow rates, and bleed plenum pressures. The simulations compared well with some of the wind-tunnel data, but uncertainties in both the windtunnel data and simulations prevented a formal evaluation of the accuracy of the simulation methods.

Performance of the University of Denver Low Turbulence, Airborne Aerosol Inlet in ACE-Asia

Science.gov (United States)

Lafleur, B.; Wilson, J. C.; Seebaugh, W. R.; Gesler, D.; Hilbert, H.; Mullen, J.; Reeves, J. M.

2002-12-01

The University of Denver Low Turbulence Inlet (DULTI) was flown on the NCAR C-130 in ACE-Asia. This inlet delivered large sample flows at velocities of a few meters per second at the exit of the inlet. This flow was slowed from the true air speed of the aircraft (100 to 150 m/s) to a few meters per second in a short diffuser with porous walls. The flow in the diffusing section was laminar. The automatic control system kept the inlet operating at near isokinetic intake velocities and in laminar flow for nearly all the flight time. The DULTI permits super micron particles to be sampled and delivered with high efficiency to the interior of the aircraft where they can be measured or collected. Because most of the air entering the inlet is removed through the porous medium, the sample flow experiences inertial enhancements. Because these enhancements occur in laminar flow, they are calculable using FLUENT. Enhancement factors are defined as the ratio of the number of particles of a given size per unit mass of air in the sample to the number of particles of that size per unit mass of air in the ambient. Experimenters divide measured mixing ratios of the aerosol by the enhancement factor to get the ambient mixing ratio of the particles. The diffuser used in ACE-Asia differed from that used in PELTI (2000), TexAQS2000 (2000) and ITCT (2002). In this poster, the flow parameters measured in the inlet in flight are compared with those calculated from FLUENT. And enhancement factors are presented for flight conditions. The enhancement factors are found to depend upon the Stokes number of particles in the entrance to the inlet and the ratio of the mass flow rate of air removed by suction to the mass flow rate delivered as sample.

Fruit Detachment and Classification Method for Strawberry Harvesting Robot

Directory of Open Access Journals (Sweden)

Guo Feng

2008-03-01

Full Text Available Fruit detachment and on-line classification is important for the development of harvesting robot. With the specific requriements of robot used for harvesting strawberries growing on the ground, a fruit detachment and classification method is introduced in this paper. OHTA color spaces based image segmentation algorithm is utilized to extract strawberry from background; Principal inertia axis of binary strawberry blob is calculated to give the pose information of fruit. Strawberry is picked selectively according to its ripeness and classified according to its shape feature. Histogram matching based method for fruit shape judgment is introduced firstly. Experiment results show that this method can achieve 93% accuracy of strawberry's stem detection, 90% above accuracy of ripeness and shape quality judgment on black and white background. With the improvement of harvesting mechanism design, this method has application potential in the field operation.

Fruit Detachment and Classification Method for Strawberry Harvesting Robot

Directory of Open Access Journals (Sweden)

Guo Feng

2008-11-01

Full Text Available Fruit detachment and on-line classification is important for the development of harvesting robot. With the specific requriements of robot used for harvesting strawberries growing on the ground, a fruit detachment and classification method is introduced in this paper. OHTA color spaces based image segmentation algorithm is utilized to extract strawberry from background; Principal inertia axis of binary strawberry blob is calculated to give the pose information of fruit. Strawberry is picked selectively according to its ripeness and classified according to its shape feature. Histogram matching based method for fruit shape judgment is introduced firstly. Experiment results show that this method can achieve 93% accuracy of strawberry's stem detection, 90% above accuracy of ripeness and shape quality judgment on black and white background. With the improvement of harvesting mechanism design, this method has application potential in the field operation.

New piezo driven gas inlet valve for fusion experiments

International Nuclear Information System (INIS)

Usselmann, E.; Hemmerich, J.L.; How, J.; Holland, D.; Orchard, J.; Winkel, T.; Schargitz, U.; Pocheim, N.

1989-01-01

The gas inlet valves used at the JET experiment are described and their performances are discussed. A new gas-valve development suitable to replace the existing valves at JET and for future use in large fusion experiments is presented. The new valve is equipped with a piezo-electric translator and has a dosing range of 0-800 mbarls -1 for D 2 . The operating mode of the valve is fail-safe closed with a leak-rate of ≤ 10 -9 mbarls -1 . The design, the test results and throughput values in dependence of filling pressure and control voltage are presented and experiences with the prototype valve as a new gas inlet valve for the JET operation are described

Numerical modelling to assess maintenance strategy management options for a small tidal inlet

Science.gov (United States)

Shaeri, Saeed; Tomlinson, Rodger; Etemad-Shahidi, Amir; Strauss, Darrell

2017-03-01

Small tidal inlets are found to be more sensitive to anthropogenic alteration than their larger counterparts. Such alterations, although typically supported by technical design reports, sometimes require amendments or modification. One of the most suitable tools to conduct the necessary studies in this regard is numerical modelling, since the behaviour of the inlet system in response to proposed remedial actions, can easily be identified. In this paper, various alternative proposals are investigated to determine the most practical and viable option to mitigate the need for ongoing maintenance at a typical small, jettied tidal inlet. The main tool to investigate the alternatives is the hydro-sedimentological modelling of the inlet system, which was performed using the Delft3D software package. The proposed alternative entrance modifications were based upon structural alterations of the inlet system (such as a jetty extension or submerged weir) and non-structural scenarios (such as a change of the time of the dredging campaign or the deposition location of the dredged material). It was concluded that whilst a detailed study is inevitable in order to achieve a comprehensive design plan, based upon the results of this study the construction of a submerged weir at the entrance channel can satisfy the needs of most of the stakeholders, with justifiable costs over a longer period.

75 FR 1582 - Endangered and Threatened Species; Designation of Critical Habitat for the Cook Inlet Beluga Whale

Science.gov (United States)

2010-01-12

... Cook Inlet Beluga Whale AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... designate critical habitat for the endangered Cook Inlet beluga whale, Delphinapterus leucas, under the... the Cook Inlet beluga whale can be found on our Web site at: http://www.fakr.noaa.gov/ FOR FURTHER...

Luminescent Measurement Systems for the Investigation of a Scramjet Inlet-Isolator

Directory of Open Access Journals (Sweden)

Azam Che Idris

2014-04-01

Full Text Available Scramjets have become a main focus of study for many researchers, due to their application as propulsive devices in hypersonic flight. This entails a detailed understanding of the fluid mechanics involved to be able to design and operate these engines with maximum efficiency even at their off-design conditions. It is the objective of the present cold-flow investigation to study and analyse experimentally the mechanics of the fluid structures encountered within a generic scramjet inlet at M = 5. Traditionally, researchers have to rely on stream-thrust analysis, which requires the complex setup of a mass flow meter, a force balance and a heat transducer in order to measure inlet-isolator performance. Alternatively, the pitot rake could be positioned at inlet-isolator exit plane, but this method is intrusive to the flow, and the number of pitot tubes is limited by the model size constraint. Thus, this urgent need for a better flow diagnostics method is addressed in this paper. Pressure-sensitive paint (PSP has been applied to investigate the flow characteristics on the compression ramp, isolator surface and isolator sidewall. Numerous shock-shock interactions, corner and shoulder separation regions, as well as shock trains were captured by the luminescent system. The performance of the scramjet inlet-isolator has been shown to improve when operated in a modest angle of attack.

Return to work and risk of subsequent detachment from employment after myocardial infarction

DEFF Research Database (Denmark)

Smedegaard, Laerke; Numé, Anna Karin; Charlot, Mette

2017-01-01

Background--Limited data are available on return to work and subsequent detachment from employment after admission for myocardial infarction (MI). Methods and Results--Using individual-level linkage of data from nationwide registries, we identified patients of working age (30-65 years) discharged...... after first-time MI in the period 1997 to 2012, who were employed before admission. To assess the cumulative incidence of return to work and detachment from employment, the Aalen Johansen estimator was used. Incidences were compared with population controls matched on age and sex. Logistic regression...... was applied to estimate odds ratios for associations between detachment from employment and age, sex, comorbidities, income, and education level. Of 39 296 patients of working age discharged after first-time MI, 22 394 (56.9%) were employed before admission. Within 1 year 91.1% (95% confidence interval [CI...

JET ENGINE INLET DISTORTION SCREEN AND DESCRIPTOR EVALUATION

Directory of Open Access Journals (Sweden)

Jiří Pečinka

2017-02-01

Full Text Available Total pressure distortion is one of the three basic flow distortions (total pressure, total temperature and swirl distortion that might appear at the inlet of a gas turbine engine (GTE during operation. Different numerical parameters are used for assessing the total pressure distortion intensity and extent. These summary descriptors are based on the distribution of total pressure in the aerodynamic interface plane. There are two descriptors largely spread around the world, however, three or four others are still in use and can be found in current references. The staff at the University of Defence decided to compare the most common descriptors using basic flow distortion patterns in order to select the most appropriate descriptor for future department research. The most common descriptors were identified based on their prevalence in widely accessible publications. The construction and use of these descriptors are reviewed in the paper. Subsequently, they are applied to radial, angular, and combined distortion patterns of different intensities and with varied mass flow rates. The tests were performed on a specially designed test bench using an electrically driven standalone industrial centrifugal compressor, sucking air through the inlet of a TJ100 small turbojet engine. Distortion screens were placed into the inlet channel to create the desired total pressure distortions. Of the three basic distortions, only the total pressure distortion descriptors were evaluated. However, both total and static pressures were collected using a multi probe rotational measurement system.

Tangential inlet supersonic separators: a novel apparatus for gas purification

DEFF Research Database (Denmark)

Wen, Chuang; Walther, Jens Honore; Yang, Yan

2016-01-01

A novel supersonic separator with a tangential inlet is designed to remove the condensable components from gas mixtures. The dynamic parameters of natural gas in the supersonic separation process are numerically calculated using the Reynolds stress turbulence model with the Peng-Robinson real gas...... be generated by the tangential inlet, and it increases to the maximum of 200 m/s at the nozzle throat due to decrease of the nozzle area of the converging part. The tangential velocity can maintain the value of about 160 m/s at the nozzle exit, and correspondingly generates the centrifugal acceleration of 3...

North Inlet • Winyah Bay (NIW) National Estuarine Research Reserve Meteorological Data, North Inlet Estuary, Georgetown, South Carolina: 1997 • 1999.

Data.gov (United States)

Baruch Institute for Marine and Coastal Sciences, Univ of South Carolina — The North Inlet Estuary and the adjacent lower northeastern section of Winyah Bay Estuary were designated as part of the National Estuarine Research Reserve System...

Detachment from Parents, Problem Behaviors, and the Moderating Role of Parental Support among Italian Adolescents

Science.gov (United States)

Pace, Ugo; Zappulla, Carla

2013-01-01

This study examined the relationship of emotional detachment from parents, parental support, and problem behaviors and focused on the unique and common contribution that detachment and parental support made to internalizing and externalizing behavioral problems. A total of 461 young adolescents, 13 to 14 years old ("M" = 13.4;…

Characteristics Air Flow in Room Chamber Test Refrigerator Household Energy Consumption with Inlet Flow Variation

Science.gov (United States)

Susanto, Edy; Idrus Alhamid, M.; Nasruddin; Budihardjo

2018-03-01

Room Chamber is the most important in making a good Testing Laboratory. In this study, the 2-D modeling conducted to assess the effect placed the inlet on designing a test chamber room energy consumption of household refrigerators. Where the geometry room chamber is rectangular and approaching the enclosure conditions. Inlet varied over the side parallel to the outlet and compared to the inlet where the bottom is made. The purpose of this study was to determine and define the characteristics of the airflow in the room chamber using CFD simulation. CFD method is used to obtain flow characteristics in detail, in the form of vector flow velocity and temperature distribution inside the chamber room. The result found that the position of the inlet parallel to the outlet causes air flow cannot move freely to the side of the floor, even flow of air moves up toward the outlet. While by making the inlet is below, the air can move freely from the bottom up to the side of the chamber room wall as well as to help uniform flow.

Analysis of DC control in double-inlet GM type pulse tube refrigerators for detectors

Science.gov (United States)

Du, B. Y.

2016-10-01

Pulse tube refrigerators have demonstrated many advantages with respect to temperature stability, vibration, reliability and lifetime among cryo-coolers for detectors. Double-inlet type pulse tube refrigerators are popular in GM type pulse tube refrigerators. The single double-inlet valve may introduce DC flow in refrigerator, which deteriorates the performance of pulse tube refrigerator. One new type of DC control mode is introduced in this paper. Two parallel-placed needle valves with opposite direction named double-valve configuration, instead of single double-inlet valve, are used in our experiment to reduce the DC flow. With two double-inlet operating, the lowest cold end temperature of 18.1K and a coolant of 1.2W@20K have been obtained. It has proved that this method is useful for controlling DC flow of the pulse tube refrigerators, which is very important to understand the characters of pulse tube refrigerators for detectors.

Effects of inlet/outlet configurations on the electrostatic capture of airborne nanoparticles and viruses

International Nuclear Information System (INIS)

Jang, Jaesung; Akin, Demir; Bashir, Rashid

2008-01-01

Motivated by capture and detection of airborne biological agents in real time with a cantilever biosensor without introducing the agents into liquids, we present the effects of inlet/outlet configurations of a homemade particle collector on the electrostatic capture of airborne 100 nm diameter nanoparticles under swirling gas flows. This particle collector has three different inlet/outlet configurations: forward inlet/outlet (FO), backward inlet/outlet (BO) and straight inlet/outlet (SO) configurations. We also present the electrostatic capture of Vaccinia viruses using the same particle collector and compare these virus measurements with the nanoparticle cases. The most particles were collected in the FO configuration. The numbers of particles captured in the BO and SO configurations were close within their standard deviations. For all the three configurations tested, the number of particles captured in the center electrode C was much smaller than those captured in the other electrodes at a flow rate of 1.1 l min −1 and an applied potential of 2 kV. Using a commercial CFD code FLUENT, we also simulated the effects of the three inlet/outlet configurations on the particle capture in terms of particle trajectories, velocities and travel times. This simulation was in a good agreement with measurements that the FO configuration is the most favorable to particle capture among the tested configurations at a flow rate of 1.1 l min −1 . The effects of particle diameters on the capture will also be discussed. This collector can be used for real-time monitoring of bioaerosols along with cantilever biosensors

Timing and conditions of clay fault gouge formation on the Naxos detachment (Cyclades, Greece)

Science.gov (United States)

Mancktelow, N.; Zwingmann, H.; Mulch, A.

2016-10-01

Clay fault gouge from the Naxos detachment (locally up to 1.0-1.5 m thick) is reported and dated for the first time. K-Ar ages on eight clay size fractions from the detachment and a minor fault in the immediate footwall have a narrow range, from 10.3 to 9.0 Ma, with an average of 9.7 ± 0.5 Ma (±1σ). These results are in excellent accord with regional and local age constraints, independently demonstrating the reliability of the method. Hydrogen δD values fall in the range -89 to -95‰, indicating interaction with infiltrating meteoric water during gouge formation, which is consistent with deposition of freshwater sediments in the hanging wall at the same time. Clay mineralogy in the detachment gouge is predominantly mixed layer illite-smectite with subordinate 1 M illite and kaolinite but without higher-temperature 2 M1 illite/mica. Clay fault gouge predominantly formed over a limited time and temperature range, potentially acting as a weak lubricant promoting movement on the Naxos detachment, with correspondingly rapid exhumation and cooling of the underlying footwall.

Silicone oil removal after rhegmatogenous retinal detachment: comparing techniques

NARCIS (Netherlands)

Tan, H. S.; Dell'omo, R.; Mura, M.

2012-01-01

Purpose To assess the outcome of silicone oil removal after rhegmatogenous retinal detachment (RRD) surgery, and to compare results of a two-port (infusion-extraction) versus a three-port (full vitrectomy) approach. Methods Primary outcome measure was the rate of redetachment. Secondary outcome

Characterization of the island divertor plasma of W7-AS stellarator in the deeply detached state with volume recombination

International Nuclear Information System (INIS)

Ramasubramanian, N.; Koenig, R.; Feng, Y.; Giannone, L.; Grigull, P.; Klinger, T.; McCormick, K.; Thomsen, H.; Wenzel, U.

2004-01-01

In the high-density H-mode of the Stellarator Wendelstein 7-AS, the plasma detaches from the island divertor targets when the line-averaged density exceeds a critical value. This quasi-stationary detachment is found to be partial and shows edge-localized, poloidally asymmetric radiation. The spectroscopic characteristics of the deeply detached plasma are reported, including evidence for volume recombination. The detached plasma radiates up to 90% of the absorbed power with larger contributions from the locations close to magnetic X-points outside the divertor region. The spectral analysis of the Balmer series indicate very high densities and low temperatures at the detached regions. The results of the spectral analysis underline the importance of three-dimensional modelling. An initial comparison is made with the latest results from EMC3-EIRENE modelling. (author)

Evolution and Impacts of a New Inlet Formed in Fire Island National Park by Superstorm Sandy (Invited)

Science.gov (United States)

Flood, R. D.; Flagg, C. N.; Goff, J. A.; Austin, J. A.; Schwab, W. C.; Denny, J. F.; Christensen, B. A.; Browne, C. M.; Saustrup, S.

2013-12-01

Superstorm Sandy impacted the New York / New Jersey area on October 29, 2012 and brought a storm surge of 1.5 to 2.5 m and waves with a significant wave height of 9.5 m to the south shore of Long Island, New York. The storm cut three inlets across Fire Island barrier islands. Two of the inlets were closed mechanically, but the third inlet, cut through a wilderness area of the Fire Island National Seashore, remains open and provides a rare opportunity to study the evolution and dynamics of an unmanaged inlet. This new inlet formed where Fire Island is narrow and is near the site of an earlier inlet that closed in 1825. Great South Bay (GSB) is located between Fire Island and the Long Island mainland. The salinity in GSB increased by 5 salinity units following the breach and has remained high. GSB has had chronic water quality issues associated with a high population density that may be moderated by flow related to the new inlet. Water flow through the new inlet is controlled by the difference between offshore tide and GSB tide, but GSB tide does not appear to have been altered by flow through the inlet. This is different from the traditional view of inlet dynamics where a balance is sought between channel cross-sectional area, tidal prism (which together give channel velocity) and longshore sediment transport. At SoMAS we have been monitoring the evolution of the new inlet since its formation. We have conducted overflights at 1 to 3 week intervals to track the changing inlet geometry and the location of flood-tidal and ebb-tidal deltas. We have also done small-boat bathymetric surveys of the channel itself every 3 to 5 weeks to track the shape and cross-sectional area of the channel. The channel was quite small shortly after the breach with a depth of about 2 m. The channel grew fast as it cut into underlying fine-grain sediments, reaching a depth of over 6 m following several late winter storms. The inlet channel initially migrated quickly to the west, but its

Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda

OpenAIRE

Chen, Fu-jen

2017-01-01

In his article "Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda" Fu-Jen Chen situates his study within today's prevailing climate of global consumption to argue that the 2007 film Juno—featuring an unconventional portrayal of the adoption triad and a cynical detachment from public values—not only trivializes and depoliticizes the practice of adoption but also serves as an ideological supplement to today's global capitalism. Furthermore, Kung Fu Panda 1 & 2 (2008; 2...

Measurement of cell adhesion force by vertical forcible detachment using an arrowhead nanoneedle and atomic force microscopy

International Nuclear Information System (INIS)

Ryu, Seunghwan; Hashizume, Yui; Mishima, Mari; Kawamura, Ryuzo; Tamura, Masato; Matsui, Hirofumi; Matsusaki, Michiya; Akashi, Mitsuru; Nakamura, Chikashi

2014-01-01

Graphical abstract: - Highlights: • We developed a method to measure cell adhesion force by detaching cell using an arrowhead nanoneedle and AFM. • A nanofilm consisting of fibronectin and gelatin was formed on cell surface to reinforce the cell cortex. • By the nanofilm lamination, detachment efficiencies of strongly adherent cell lines were improved markedly. - Abstract: The properties of substrates and extracellular matrices (ECM) are important factors governing the functions and fates of mammalian adherent cells. For example, substrate stiffness often affects cell differentiation. At focal adhesions, clustered–integrin bindings link cells mechanically to the ECM. In order to quantitate the affinity between cell and substrate, the cell adhesion force must be measured for single cells. In this study, forcible detachment of a single cell in the vertical direction using AFM was carried out, allowing breakage of the integrin–substrate bindings. An AFM tip was fabricated into an arrowhead shape to detach the cell from the substrate. Peak force observed in the recorded force curve during probe retraction was defined as the adhesion force, and was analyzed for various types of cells. Some of the cell types adhered so strongly that they could not be picked up because of plasma membrane breakage by the arrowhead probe. To address this problem, a technique to reinforce the cellular membrane with layer-by-layer nanofilms composed of fibronectin and gelatin helped to improve insertion efficiency and to prevent cell membrane rupture during the detachment process, allowing successful detachment of the cells. This method for detaching cells, involving cellular membrane reinforcement, may be beneficial for evaluating true cell adhesion forces in various cell types

The effect of inlet distorted flow on steady and unsteady performance of a centrifugal compressor

International Nuclear Information System (INIS)

Park, Jae Hyoung; Kang, Shin Hyoung

2005-01-01

Effects of inlet distorted flow on performance, stall and surge are experimentally investigated for a high-speed centrifugal compressor. Tested results for the distorted inlet flow cases are compared with the result of the undistorted one. The performance of compressor is slightly deteriorated due to the inlet distortion. The inlet distortion does not affect the number of stall cell and the propagation velocity. It also does not change stall inception flow rate. However, as the distortion increases, stall starts at the higher flow rate for low speed at the lower flow rate for high speed. For 50,000 rpm stall occurs as the flow rate decreases, however disappears for the smaller flow rate. This is due to the interaction of surge and stall. After the stall and surge interact, the number of stall cell decreases

Two-Dimensional Bifurcated Inlet Variable Cowl Lip Test Completed in 10- by 10-Foot Supersonic Wind Tunnel

Science.gov (United States)

Hoffman, T. R.

2000-01-01

Researchers at the NASA Glenn Research Center at Lewis Field successfully tested a variable cowl lip inlet at simulated takeoff conditions in Glenn s 10- by 10-Foot Supersonic Wind Tunnel (10x10 SWT) as part of the High-Speed Research Program. The test was a follow-on to the Two-Dimensional Bifurcated (2DB) Inlet/Engine test. At the takeoff condition for a High-Speed Civil Transport aircraft, the inlet must provide adequate airflow to the engine with an acceptable distortion level and high-pressure recovery. The test was conducted to study the effectiveness of installing two rotating lips on the 2DB Inlet cowls to increase mass flow rate and eliminate or reduce boundary layer flow separation near the lips. Hardware was mounted vertically in the test section so that it extended through the tunnel ceiling and that the 2DB Inlet was exposed to the atmosphere above the test section. The tunnel was configured in the aerodynamic mode, and exhausters were used to pump down the tunnel to vacuum levels and to provide a maximum flow rate of approximately 58 lb/sec. The test determined the (1) maximum flow in the 2DB Inlet for each variable cowl lip, (2) distortion level and pressure recovery for each lip configuration, (3) boundary layer conditions near variable lips inside the 2DB Inlet, (4) effects of a wing structure adjacent to the 2DB Inlet, and (5) effects of different 2DB Inlet exit configurations. It also employed flow visualization to generate enough qualitative data on variable lips to optimize the variable lip concept. This test was a collaborative effort between the Boeing Company and Glenn. Extensive inhouse support at Glenn contributed significantly to the progress and accomplishment of this test.

Scleral buckling for retinal detachment in Ibadan, Sub-Saharan Africa: anatomical and visual outcome

Directory of Open Access Journals (Sweden)

Oluleye TS

2013-05-01

Full Text Available TS Oluleye, OA Ibrahim, BA OlusanyaRetina and Vitreous Unit, Department of Ophthalmology, University College Hospital, Ibadan, NigeriaBackground: Scleral buckle surgery is not a commonly performed surgical procedure in Sub-Saharan Africa due to a paucity of trained vitreo retinal surgeons. The aim of the study was to review sclera buckle procedures with a view to evaluating the anatomical and visual outcomes.Methods: Case records of patients that had scleral buckle surgery at the Retina Unit of the University College Hospital, Ibadan, Nigeria, between 2007 and 2010 were reviewed. Information retrieved included patients' demographics, duration of symptoms, and presenting vision. Other information included site of retinal break, extent of retinal detachment, involvement of the fellow eye, and macular involvement. Postoperative retina reattachment and postoperative visual acuity were also recorded. Proportions and percentages were used to analyze data.Results: Forty five eyes of 42 patients were studied with a male to female ratio of 1.6:1. The mean age was 47.7 years (±17.6 years. The median duration before presentation was 3 months (range: 5 days – 156 months. Subtotal retinal detachment was found in 35 eyes (77.8% while total retinal detachment occurred in ten eyes (22.2%. Thirty four eyes (75.6% had "macular off" detachments. At 6 weeks, there was an improvement in visual acuity in 23 eyes (51.1%, while visual acuity remained the same in nine eyes (20% and was worse in 13 eyes (28.9%. Anatomical attachment was seen in 43 eyes (95.6% on the operation table, in 40 eyes (90.9% at first day postoperatively and in 32 eyes (86.5% at 6 weeks after surgery.Conclusion: Outcome of sclera buckle surgery for rhegmatogenous retinal detachment may be improved in developing countries of Sub Sahara Africa if adequate awareness is created to educate the populace on early presentation.Keywords: retinal detachment, scleral buckle surgery, anatomical and visual

Effectiveness of methods for detaching orthodontic implants likely to fracture upon rotational torque – an animal study

Science.gov (United States)

Nakagaki, Susumu; Yasuda, Yoshitaka; Handa, Keisuke; Koike, Toshiyuki; Saito, Takashi; Mizoguchi, Itaru

2016-01-01

Abstract Orthodontic implants may fracture at the cortical bone level upon rotational torque. The impacted fragment can be detached by a range of methods, which are all more or less time‐consuming and injurious to the cortical bone. The aim of this study was to compare three different methods for detaching an orthodontic implant impacted in cortical bone. Health Sciences University of Hokkaido animal ethics committee approved the study protocol. Orthodontic titanium‐alloy (Ti‐6Al‐4 V) implants were placed bilaterally on the buccal side of the mandible of beagle dogs. Subsequently, the implants were detached using either a low‐speed handpiece with a round bur, alternatively by use of a low‐power or a high‐power ultrasonic instrument. In the first experiment, 56 orthodontic implants were placed into the dissected mandible from 7 animals. The methods for detachment were compared with respect to time interval, as well as associated undesirable bone loss as appraised by use of cone‐beam computed tomography. In experiment two, 2x2 implants were placed bilaterally in the mandible of 8 animals and subsequently detached by manual rotational torque, and the described three methods for detachment. The implant socket was investigated histologically as a function of removal method immediately after removal, and after 1, 3 and 8 weeks and contrasted with the healing of the socket of the implant that was detached by manual rotational torque. Statistical significance was appraised by the use of non‐parametric Kruskal‐Wallis one‐way analysis of variance. The method using the low‐power ultrasonic required significantly longer removal time versus the two other methods, i.e. high‐power ultrasonic and low‐speed handpiece with a round bur (p Orthodontic implants likely to fracture upon rotational torque or impacted fractured fragments should be detached preferably with an ultrasonic instrument, because of less associated bone loss and more rapid bone

Aero-Thermo-Structural Analysis of Inlet for Rocket Based Combined Cycle Engines

Science.gov (United States)

Shivakumar, K. N.; Challa, Preeti; Sree, Dave; Reddy, Dhanireddy R. (Technical Monitor)

2000-01-01

NASA has been developing advanced space transportation concepts and technologies to make access to space less costly. One such concept is the reusable vehicles with short turn-around times. The NASA Glenn Research Center's concept vehicle is the Trailblazer powered by a rocket-based combined cycle (RBCC) engine. Inlet is one of the most important components of the RBCC engine. This paper presents fluid flow, thermal, and structural analysis of the inlet for Mach 6 free stream velocity for fully supersonic and supercritical with backpressure conditions. The results concluded that the fully supersonic condition was the most severe case and the largest stresses occur in the ceramic matrix composite layer of the inlet cowl. The maximum tensile and the compressive stresses were at least 3.8 and 3.4, respectively, times less than the associated material strength.

Occupational Lifting Tasks and Retinal Detachment in Non-Myopics and Myopics: Extended Analysis of a Case-control Study

OpenAIRE

Mattioli, Stefano; Curti, Stefania; De Fazio, Rocco; Cooke, Robin Mt; Zanardi, Francesca; Bonfiglioli, Roberta; Farioli, Andrea; Violante, Francesco S.

2012-01-01

Objectives: Lifting heavy weights involves the Valsalva manoeuvre, which leads to intraocular pressure spikes. We used data from a case-control study to further investigate the hypothesis that occupational lifting is a risk factor for retinal detachment. Methods: The study population included 48 cases (patients operated for retinal detachment) and 84 controls (outpatients attending an eye clinic). The odds ratios (OR) of idiopathic retinal detachment were estimated with a logistic regressi...

Psychological detachment from work during non-work time: linear or curvilinear relations with mental health and work engagement?

OpenAIRE

SHIMAZU, Akihito; MATSUDAIRA, Ko; DE JONGE, Jan; TOSAKA, Naoya; WATANABE, Kazuhiro; TAKAHASHI, Masaya

2016-01-01

This study examined whether a higher level of psychological detachment during non-work time is associated with better employee mental health (Hypothesis 1), and examined whether psychological detachment has a curvilinear relation (inverted U-shaped pattern) with work engagement (Hypothesis 2). A large cross-sectional Internet survey was conducted among registered monitors of an Internet survey company in Japan. The questionnaire included scales for psychological detachment, employee mental he...

Exchange inlet optimization by genetic algorithm for improved RBCC performance

Science.gov (United States)

Chorkawy, G.; Etele, J.

2017-09-01

A genetic algorithm based on real parameter representation using a variable selection pressure and variable probability of mutation is used to optimize an annular air breathing rocket inlet called the Exchange Inlet. A rapid and accurate design method which provides estimates for air breathing, mixing, and isentropic flow performance is used as the engine of the optimization routine. Comparison to detailed numerical simulations show that the design method yields desired exit Mach numbers to within approximately 1% over 75% of the annular exit area and predicts entrained air massflows to between 1% and 9% of numerically simulated values depending on the flight condition. Optimum designs are shown to be obtained within approximately 8000 fitness function evaluations in a search space on the order of 106. The method is also shown to be able to identify beneficial values for particular alleles when they exist while showing the ability to handle cases where physical and aphysical designs co-exist at particular values of a subset of alleles within a gene. For an air breathing engine based on a hydrogen fuelled rocket an exchange inlet is designed which yields a predicted air entrainment ratio within 95% of the theoretical maximum.

[Two cases of retinal detachment following laser in Situ keratomileusis repaired by scleral buckling surgery].

Science.gov (United States)

Onguchi, Tatsuya; Eshita, Tadahiko; Mita, Shinji; Ishida, Susumu; Shinoda, Kei; Kitamura, Shizuaki; Kawashima, Shinichi; Inoue, Makoto; Oguchi, Yoshihisa; Toda, Ikuko; Kato, Naoko

2002-02-01

As laser in situ keratomileusis (LASIK) becomes the treatment of choice in the field of refractive surgery, postoperative rhegmatogenous retinal detachment has also begun to occur. However, since it has not been reported yet here in Japan, we report two cases of retinal detachment following LASIK with suggestions based on our experience. A 34-year-old male(Case 1) and a 26-year-old male(Case 2) suffered from retinal detachment one month and eight months after LASIK, respectively. Contributing retinal breaks were a horseshoe tear in Case 1 and atrophic holes in the lattice degeneration in Case 2. Each patient underwent partial scleral buckling with no intraoperative complication, resulting in successful retinal reattachment. Postoperatively, myopic changes developed and persisted one month in Case 1 and several months in Case 2. Great attention should be paid to the possibility of postoperative myopia after a repair of retinal detachment following LASIK. Thus, we stress the necessity of close cooperation between LASIK surgeons and vitreoretinal surgeons to settle the matter.

Long-term evolution of sand waves in the Marsdiep inlet. II: Relation to hydrodynamics

Science.gov (United States)

Buijsman, Maarten C.; Ridderinkhof, Herman

2008-05-01

A discussion is presented about the mechanisms that govern the spatial and seasonal variability in sand-wave height and migration speed in the 4 km wide Marsdiep tidal inlet, the Netherlands. Since 1998, current velocities and water depths have been recorded with an ADCP that is mounted under the ferry 'Schulpengat'. In this paper, the current measurements were used to explain the sand-wave observations presented in Buijsman and Ridderinkhof [this issue. Long-term evolution of sand waves in the Marsdiep inlet. I: high-resolution observations. Continental Shelf Research, doi: 10.1016/j.csr.2007.10.011]. Across nearly the entire inlet, the sand waves migrate in the flood direction. In the flood-dominated southern part of the inlet, the 'measured' (i.e. based on sand-wave shape and migration speed) and predicted bedload transport agree in direction, magnitude, and trends, whereas in the ebb-dominated northern part the predicted bedload and suspended load transport is opposite to the sand-wave migration. In the southern part, 55% of the bedload transport is due to tidal asymmetries and 45% due to residual currents. In addition to the well-known tidal asymmetries, asymmetries that arise from the interaction of M2 and its overtides with S2 and its compound tides are also important. It is hypothesised that in the northern part of the inlet the advection of suspended sand and lag effects govern the sand-wave migration. The relative importance of suspended load transport also explains why the sand waves have smaller lee-slope angles, are smaller, more rounded, and more three-dimensional in the northern half of the inlet. The sand waves in this part of the inlet feature the largest seasonal variability in height and migration speed. This seasonal variability may be attributed to the tides or a seasonal fluctuation in fall velocity. In both cases sediment transport is enhanced in winter, increasing sand-wave migration and decreasing sand-wave height. The influence of storms

Repair of Total Tractional Retinal Detachment in Norrie Disease: Report of Technique and Successful Surgical Outcome.

Science.gov (United States)

Todorich, Bozho; Thanos, Aristomenis; Yonekawa, Yoshihiro; Capone, Antonio

2017-03-01

Norrie disease is a rare, but devastating cause of pediatric retinal detachment, universally portending a poor visual prognosis. This paper describes successful surgical management of an infant with total retinal detachment associated with Norrie disease mutation. The infant was a full-term white male who presented with bilateral total funnel retinal detachments (RDs). He underwent genetic testing, which demonstrated single-point mutation 133 G>A transition in exon 2 of the NDP gene. The retinal detachment was managed with translimbal iridectomy, lensectomy, capsulectomy, and vitrectomy. Careful dissection of the retrolental membranes resulted in opening of the funnel. Single-stage surgery in this child's eye achieved re-attachment of the posterior pole with progressive reabsorption of subretinal fluid and cholesterol without the need for external drainage. Fluorescein angiography, performed at 2 months postoperatively, demonstrated perfusion of major vascular arcades, but with significant abnormalities and aneurysmal changes of higher-order vessels, suggestive of retinal and vascular dysplasia. The child has maintained brisk light perception vision. Early surgical intervention with careful dissection of tractional tissues can potentially result in good anatomic outcomes in some patients with Norrie disease-associated retinal detachment. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:260-262.]. Copyright 2017, SLACK Incorporated.

The effect of inclusion of inlets in dual drainage modelling

Science.gov (United States)

Chang, Tsang-Jung; Wang, Chia-Ho; Chen, Albert S.; Djordjević, Slobodan

2018-04-01

In coupled sewer and surface flood modelling approaches, the flow process in gullies is often ignored although the overland flow is drained to sewer network via inlets and gullies. Therefore, the flow entering inlets is transferred to the sewer network immediately, which may lead to a different flood estimation than the reality. In this paper, we compared two modelling approach with and without considering the flow processes in gullies in the coupled sewer and surface modelling. Three historical flood events were adopted for model calibration and validation. The results showed that the inclusion of flow process in gullies can further improve the accuracy of urban flood modelling.

Cold water inlet in solar tanks - valuation

DEFF Research Database (Denmark)

Andersen, Elsa

1999-01-01

The aim of the project is to make a proposal for how to value a storage tank with a poor design of the cold water inlet. Based on measurements and calculations a number of curves, which are valid for this valuation, are worked out. Based on a simple test with a uniform heated storage tank the rat...

Characteristics and Surgical Outcomes of Rhegmatogenous Retinal Detachment Following Myopic LASIK

Science.gov (United States)

Daftarian, Narsis; Dehghan, Mohammad-Hossein; Ahmadieh, Hamid; Soheilian, Masoud; Karkhaneh, Reza; Lashay, Alireza; Mirshahi, Ahmad; Parhizkar, Hamid; Kazemimoghadam, Mohsen; Modarreszadeh, Mehdi; Hashemi, Masih; Fadaei, Mojtaba; Entezari, Morteza

2009-01-01

Purpose To describe the clinical features and surgical outcomes of rhegmatogenous retinal detachment (RRD) following myopic laser in situ keratomileusis (LASIK). Methods In a retrospective, non-comparative case series, 46 eyes that had undergone vitreoretinal surgery for management of RRD following myopic LASIK were identified. Data was reviewed with emphasis on characteristics of the RRD, employed surgical techniques, and anatomic and visual outcomes. Results Mean pre-LASIK myopia was −9.7±3.9 (range −4.00 to −18.00) diopters (D). Mean interval between LASIK and development of RRD was 11.6±11.2 months. Posterior vitreous detachment was present in 44 eyes (95.6%). The retinal breaks included flap tears in 36 (78.3%) eyes, giant tears in 8 (17.4%) eyes and atrophic holes in 2 (4.3%) eyes. In eyes with flap tears, the breaks were multiple, large or posterior to the equator in 24(66.7%) eyes. Retinal breaks were related to lattice degeneration in 20 (43.5%) eyes of which, three had history of prophylactic barrier laser photocoagulation. Scleral buckling was performed as the initial procedure in 32 (69.6%) eyes and primary vitrectomy was undertaken in 14 (30.4%) eyes. The initial surgical procedure failed in 14 (30.4%) eyes due to proliferative vitreoretinopathy (PVR). Retinal reattachment was finally achieved in 43 (93.4%) eyes. Postoperative visual acuity ≥20/40 and ≥20/200 was achieved in 16 (34.8%) and 25 (54.3%) eyes, respectively. Conclusion Post-LASIK retinal detachment has a complex nature in eyes with moderate to high myopia. The retinal detachment is complex in terms of size, number and location of retinal breaks, is associated with a high rate of PVR and entails unfavorable visual outcomes. PMID:23198065

Recombination and detachment in oxygen discharges: the role of metastable oxygen molecules

International Nuclear Information System (INIS)

Gudmundsson, J T

2004-01-01

A global (volume averaged) model of oxygen discharges is used to study the transition from a recombination dominated discharge to a detachment dominated discharge. The model includes the metastable oxygen molecules O 2 (a 1 Δ g ) and O 2 (b 1 Σ g + ) and the three Herzberg states O 2 (A 3 Σ u + , A' 3 Δ u , c 1 Σ u - ). Dissociative attachment of the oxygen molecule in the ground state O 2 ( 3 Σ g - ) and the metastable oxygen molecule O 2 (a 1 Δ g ) are the dominating channels for creation of the negative oxygen ion O - . At high pressures, dissociative attachment of the Herzberg states contributes significantly to the creation of the negative oxygen ion, O - . The detachment by a collision of the metastable oxygen molecule O 2 (b 1 Σ g + ) with the oxygen ion, O - , is a significant loss process for the O - at pressures above 10 mTorr. Its contribution to the loss is more significant at a lower applied power, but at the higher pressures it is always significant. Detachment by collision with O( 3 P) is also an important loss mechanism for O - . We find that ion-ion recombination is the dominating loss process for negative ions in oxygen discharges at low pressures and calculate the critical pressure where the contributions of recombination reactions and detachment reactions are equal. This critical pressure depends on the applied power, increases with applied power and is in the range 5-14 mTorr in the pressure and power range investigated

Prediction of bubble detachment diameter in flow boiling based on force analysis

International Nuclear Information System (INIS)

Chen Deqi; Pan Liangming; Ren Song

2012-01-01

Highlights: ► All the forces acting on the growing bubbles are taken into account in the model. ► The bubble contact diameter has significant effect on bubble detachment. ► Bubble growth force and surface tension are more significant in narrow channel. ► A good agreement between the predicted and the measured results is achieved. - Abstract: Bubble detachment diameter is one of the key parameters in the study of bubble dynamics and boiling heat transfer, and it is hard to be measured in a boiling system. In order to predict the bubble detachment diameter, a theoretical model is proposed based on forces analysis in this paper. All the forces acting on a bubble are taken into account to establish a model for different flow boiling configurations, including narrow and conventional channels, upward, downward and horizontal flows. A correlation of bubble contact circle diameter is adopted in this study, and it is found that the bubble contact circle diameter has significant effect on bubble detachment. A new correlation taking the bubble contact circle diameter into account for the evaluation of bubble growth force is proposed in this study, and it is found that the bubble growth force and surface tension force are more significant in narrow channel when comparing with that in conventional channel. A visual experiment was carried out in order to verify present model; and the experimental data from published literature are used also. A good agreement between predicted and measured results is achieved.

77 FR 6065 - Proposed Information Collection; Comment Request; Cook Inlet Beluga Whale Economic Survey

Science.gov (United States)

2012-02-07

... Collection; Comment Request; Cook Inlet Beluga Whale Economic Survey AGENCY: National Oceanic and Atmospheric... beluga whales found in the Cook Inlet of Alaska is one of five distinct population segments in United... beluga whale, such as population increases, are primarily the result of the non- consumptive value people...

The radontechnical process of the sub-slab suction system in detached, semi-detached and terraced houses; Imupistejaerjestelmaen radontekninen toiminta eri tyyppisissae pien- ja rivitaloissa

Energy Technology Data Exchange (ETDEWEB)

Kettunen, A.V.; Rissanen, R.; Viljanen, M. [Helsinki Univ. of Technology, Otaniemi (Finland). Lab. of Structural Engineering and Building Physics; Arvela, H. [Finnish Centre for Radiation and Nuclear Safety, Helsinki (Finland)

1997-12-31

The sub-slab suction system is a repair method for decreasing radon transfer from soil to indoor air in houses. The sub-slab suction system changes the flow field with the aim to reduce the radon content under the ground slab or/and changes the flow direction from indoor air to foundation soil. The study is divided into the theoretical and experimental part. The theoretical part concentrates on solving the factors affecting the sub-slab suction system taking into consideration features of old houses. The experimental part uses the results of the theoretical part when the level and the type of the suction point had been chosen. The effect of the sub-slab suction system was tested with pressure difference experiments and the radon content measurements in 26 different, typical Finnish detached, semi-detached and terrace houses.

Detached Concern of Forensic Mental Health Nurses in Therapeutic Relationships With Patients: The Application of the Early Recognition Method Related to Detached Concern

NARCIS (Netherlands)

Fluttert, F.A.J.; Meijel, B.K.G. van; Nijman, H.L.I.; Björkly, S.; Grypdonck, M.H.F.

2010-01-01

Objective - Improvement of the interaction between forensic mental health nurses and patients may lead to a reduction of inpatient violence. The concept under study is detached concern, which refers to nurses' skills to neutralize the emotional appeal of patients by a balanced attitude between

Spectral domain optical coherence tomography imaging of subretinal bands associated with chronic retinal detachments

OpenAIRE

Kothari, Nikisha; Kuriyan, Ajay E; Flynn, Harry W

2016-01-01

Nikisha Kothari, Ajay E Kuriyan, Harry W Flynn JrDepartment of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USAAbstract: We report three patients with subretinal bands associated with retinal detachment in chronic retinal detachments who underwent successful retinal reattachment. Subretinal bands before and after surgery can be identified on clinical examination and spectral domain optical coherence tomography. Removal of subr...

Improving the performances of H-Darrieus cross-flow turbines through proper detached end plate designs

Science.gov (United States)

Villeneuve, Thierry; Boudreau, Matthieu; Dumas, Guy; CFD Laboratory LMFN Team

2017-11-01

Previous studies on H-Darrieus cross-flow turbines have highlighted the fact that their performances are highly sensitive to the detrimental effects associated with the blades tips. Wingtip devices could be designed in order to attenuate these effects, but the benefits of such devices are always impaired by their added viscous drag since they are moving with the turbine's blades. In this context, the development of fixed and detached end plates, i.e., which are not in contact with the turbine's blades, could reduce the tip losses without the undesirable added drag of typical wingtip devices moving with the blades. The case of a single stationary blade with detached end plates has first been investigated with RANS simulations in order to understand the mechanisms responsible for the increase of the blade's lift. An analysis of the vorticity lines' dynamics provides crucial insights into the effects of the gap width between the blade and the detached end plate on the blade's loading and on the intensity of the tip vortices. Based on these observations, various configurations of detached end plates are tested on cross-flow turbines via RANS and DDES simulations. Preliminary results show that appropriate detached end plates can significantly increase the turbines' efficiency. The authors gratefully acknowledge the Natural Sciences and Engineering Research Council of Canada (NSERC) for their financial support as well as Compute Canada and Calcul Québec for their supercomputer allocations.

Ocular coherence tomographic examination of postoperative foveal architecture after scleral buckling vs vitrectomy for macular off retinal detachment.

LENUS (Irish Health Repository)

Gibran, S K

2012-02-03

AIMS: This pilot study uses Optical Coherence Tomography (OCT) imaging to compare the difference in foveal architecture after successful retinal detachment (RD) surgery by scleral buckling or pars plana vitrectomy (PPV). METHODS: Prospective recruitment of patients with macular off RDs. Detachment surgery was undertaken by scleral buckling, external drainage, and air injection (group 1) or by PPV (group 2). Postoperatively patients had clinical examinations and OCT at 1, 3, 6, and 12 months. If abnormalities persisted, a further OCT was obtained at 18 months. RESULTS: Retinal reattachment, including clinical macular reattachment, was achieved in all cases within 24 h postoperatively. In group 1 (n=22), postoperative OCT showed persistent foveal detachment in 63% of cases (n=14) at 1 and 3 months. At 6 and 12 months, 36% (n=8) and 9% (n=2) had a persistent foveal detachment, respectively, and at 18 months, foveal detachment eventually. In group 2 (n=21), postoperative OCT showed an attached fovea in all cases; however, foveal thickening suggesting intraretinal oedema was present in all cases. The oedematous appearance of retina on OCT settled in 1-3 months. No foveal abnormality was seen at 6 and 12 months postoperatively. CONCLUSIONS: A high proportion of patients with successful retinal reattachment surgery by scleral buckling had foveal detachments postoperatively. No cases who had PPV had foveal detachments; however, transient retinal oedema was evident in all cases. The aetiology of these changes is unknown and warrants further investigation, as there is the potential of a long-term effect on vision.

Macula-Sparing rhegmatogenous retinal detachment: Is emergent surgery necessary?

Directory of Open Access Journals (Sweden)

Sasan Mahmoudi

2016-01-01

Full Text Available The status of the macula is a significant factor in determining final visual outcomes in rhegmatogenous retinal detachment (RRD and should be considered in the timing of surgical repair. Several studies have shown that macula-involving RRDs attain similar visual and anatomic outcomes when surgery is performed within seven days as compared to emergent surgery (within 24 hours. In contrast, surgery prior to macular detachment in macula-sparing RRDs generally yields the best visual outcomes. In the case of macula-sparing RRDs, it is not clear how long the macula may remain attached, therefore, standard practice dictates emergent surgery. Timing of presentation, examination findings, case complexity, co-existing medical conditions, surgeon expertise, and timing and quality of access to operating facilities and staff, however, should all be considered in determining whether a macula-sparing RRD requires immediate intervention or if equivalent visual and possibly better overall outcomes can be achieved with scheduled surgery within an appropriate time frame.

Acute lymphoblastic leukemia presenting with bilateral serous macular detachment

Directory of Open Access Journals (Sweden)

Luisa Vieira

2015-12-01

Full Text Available ABSTRACT Acute lymphoblastic leukemia is a malignant hematopoietic neoplasia, which is rare in adults. Although ocular fundus alterations may be commonly observed in the course of the disease, such alterations are rarely the presenting signs of the disease. Here we describe the case of a patient with painless and progressive loss of visual acuity (right eye, 2/10; left eye, 3/10 developing over two weeks, accompanied by fever and cervical lymphadenopathy. Fundus examination showed bilateral macular serous detachment, which was confirmed by optical coherence tomography. Fluorescein angiography revealed hyperfluorescent pinpoints in the posterior poles. The limits of the macular detachment were revealed in the late phase of the angiogram. The results of blood count analysis triggered a thorough, systematic patient examination. The diagnosis of acute lymphoblastic leukemia B (CD10+ was established, and intensive systemic chemotherapy was immediately initiated. One year after the diagnosis, the patient remains in complete remission without any ophthalmologic alterations.

AFSC/REFM: Cook Inlet Beluga Whale Economic Survey 2013

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project was to collect data to understand the publics preferences for protecting the Cook Inlet beluga whale (CIBW), a distinct population...

An experimental study of the effects of bodyside compression on forward swept sidewall compression inlets ingesting a turbulent boundary layer

Science.gov (United States)

Rodi, Patrick E.

1993-01-01

Forward swept sidewall compression inlets have been tested in the Mach 4 Blowdown Facility at the NASA Langley Research Center to study the effects of bodyside compression surfaces on inlet performance in the presence of an incoming turbulent boundary layer. The measurements include mass flow capture and mean surface pressure distributions obtained during simulated combustion pressure increases downstream of the inlet. The kerosene-lampblack surface tracer technique has been used to obtain patterns of the local wall shear stress direction. Inlet performance is evaluated using starting and unstarting characteristics, mass capture, mean surface pressure distributions and permissible back pressure limits. The results indicate that inlet performance can be improved with selected bodyside compression surfaces placed between the inlet sidewalls.

A CFD Study on Inlet Plenum Flow Field of Pebble Bed Reactor

International Nuclear Information System (INIS)

Kim, Min Hwan; Lee, Won Jae; Chang, Jong Hwa

2005-01-01

High temperature gas cooled reactor, largely divided into two types of PBR (Pebble Bed Reactor) and PMR (Prismatic Modular Reactor), has becomes great interest of researchers in connection with the hydrogen production. KAERI has started a project to develop the gas cooled reactor for the hydrogen production and has been doing in-depth study for selecting the reactor type between PBR and PMR. As a part of the study, PBMR (Pebble Bed Modular Reactor) was selected as a reference PBR reactor for the CFD analysis and the flow field of its inlet plenum was simulated with computational fluid dynamics program CFX5. Due to asymmetrical arrangement of pipes to the inlet plenum, non-uniform flow distribution has been expected to occur, giving rise to non-uniform power distribution at the core. Flow fields of different arrangement of inlet pipes were also investigated, as one of measures to reduce the non-uniformity

Quantification of tidal inlet morphodynamics using high-resolution MBES and LiDAR

DEFF Research Database (Denmark)

Ernstsen, Verner Brandbyge; Lefebvre, Alice; Fraccascia, Serena

-bathymetric surveys using high-resolution red and green Light Detection And Ranging (LiDAR). Detailed digital elevation models with a grid cell size of 1 m x 1 m were generated and analysed geomorphometrically. The analyses reveal a main ebb-directed net sand transport in the main channel; however, due...... to the geometry of the main channel, displaying a confluent meander bend, confined areas in the main channel are characterised by an opposite-directed net sand transport. In the inter-tidal areas the main net sand transport is flood-directed. However, also here the analyses reveal the existence of oblique second...... is transported from the inlet channel to the intertidal flat. Therefore, in addition to the typical main sand transport directions with net export in the inlet channel and net import over the adjacent inter-tidal flats, these investigations suggest an exchange and possible recirculation of sand between the inlet...

Portable apparatus for containing and regulating flow of a liquid into a drainage inlet

International Nuclear Information System (INIS)

Warren, R.E.

1991-01-01

This patent describes a method of using an apparatus suitable for containing a mixture of spilled petroleum liquid and water and regulating the flow of water into a storm drain, having a drainage inlet with a recess area extending about a perimeter of the drainage inlet, while minimizing the flow of the petroleum liquid into the storm drain, the apparatus comprising, flange means, defining a central opening therein, for engaging the recess area of the storm drain, the flange means being substantially the same size and shape as a cover of the storm drain so that when the cover is removed from the storm drain, the method comprising the steps of: positioning the apparatus over a storm drain with the flange means being received and supported by the recess area of the storm drain with the central opening overlying the drainage inlet; allowing the mixture of petroleum liquid and water to collect around the apparatus; controlling the position of the movable hollow member, relative to the flange means, to control the flow of water into the drainage inlet, through the sidewall and central openings, while maintaining the petroleum liquid floating on the water and preventing entry of the petroleum liquid into the at least sidewall opening; and collecting the petroleum liquid after a sufficient quantity of water has been allowed to flow into the drainage inlet

ASSESSING CLIMATE CHANGE IMPACTS ON THE STABILITY OF SMALL TIDAL INLETS: Part 2- DATA RICH ENVIRONMENTS.

Science.gov (United States)

Duong, Trang Minh; Ranasinghe, Roshanka; Thatcher, Marcus; Mahanama, Sarith; Wang, Zheng Bing; Dissanayake, Pushpa Kumara; Hemer, Mark; Luijendijk, Arjen; Bamunawala, Janaka; Roelvink, Dano; Walstra, Dirkjan

2018-01-01

Climate change (CC) is likely to affect the thousands of bar-built or barrier estuaries (here referred to as Small tidal inlets - STIs) around the world. Any such CC impacts on the stability of STIs, which governs the dynamics of STIs as well as that of the inlet-adjacent coastline, can result in significant socio-economic consequences due to the heavy human utilisation of these systems and their surrounds. This article demonstrates the application of a process based snap-shot modelling approach, using the coastal morphodynamic model Delft3D , to 3 case study sites representing the 3 main STI types; Permanently open, locationally stable inlets (Type 1), Permanently open, alongshore migrating inlets (Type 2) and Seasonally/Intermittently open, locationally stable inlets (Type 3). The 3 case study sites (Negombo lagoon - Type 1, Kalutara lagoon - Type 2, and Maha Oya river - Type 3) are all located along the southwest coast of Sri Lanka. After successful hydrodynamic and morphodynamic model validation at the 3 case study sites, CC impact assessment are undertaken for a high end greenhouse gas emission scenario. Future CC modified wave and riverflow conditions are derived from a regional scale application of spectral wave models (WaveWatch III and SWAN) and catchment scale applications of a hydrologic model (CLSM) respectively, both of which are forced with IPCC Global Climate Model output dynamically downscaled to ~ 50 km resolution over the study area with the stretched grid Conformal Cubic Atmospheric Model CCAM. Results show that while all 3 case study STIs will experience significant CC driven variations in their level of stability, none of them will change Type by the year 2100. Specifically, the level of stability of the Type 1 inlet will decrease from 'Good' to 'Fair to poor' by 2100, while the level of (locational) stability of the Type 2 inlet will also decrease with a doubling of the annual migration distance. Conversely, the stability of the Type 3 inlet

Effectiveness of EDTA and Modified Salt Solution to Detach and Kill Cells from Enterococcus faecalis Biofilm.

Science.gov (United States)

de Almeida, Josiane; Hoogenkamp, Michel; Felippe, Wilson T; Crielaard, Wim; van der Waal, Suzette V

2016-02-01

Disruption of the matrix of endodontic biofilms will aid in their removal from a root canal. Therefore, the aim of this study was to investigate the efficacy of EDTA and a modified salt solution (MSS) to detach bacteria from biofilms. Forty-eight-hour-old Enterococcus faecalis biofilms were grown on glass coverslips and then treated for 1 hour by immersion in 17% EDTA or MSS. Phosphate-buffered saline served as a negative control. Then, residual biofilm cells on the substrate and the detached cells in the supernatant were collected. Viability was verified by the colony-forming unit (CFU) counting method. Propidium monoazide (PMA) treatment in conjunction with quantitative polymerase chain reaction (qPCR) was also performed to detect the presence of E. faecalis 16S ribonucleic RNA genes. Data were analyzed using 1-way analysis of variance and Tukey or Kruskal-Wallis and Dunn tests. The Pearson R test evaluated the correlation between results from CFU and PMA (α = 5%). qPCR showed that EDTA detached 99% of biofilm cells, and MSS detached 94% of biofilm cells (both P < .001). In contrast to EDTA, MSS was highly antimicrobial. The treatment promoted an ample log 7 reduction of the attached cells (P < .001), and almost no live cells were detected in the supernatant (P < .001). Positive correlations between CFU and qPCR with PMA were observed (r = 0.959 and r = 0.729). EDTA detached cells in biofilms with a minor antimicrobial effect. Besides a great antimicrobial effect, MSS also detached biofilm cells. These dispersals of biofilms give insights into new endodontic biofilm removal strategies. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Effects of Near Soil Surface Characteristics on the Soil Detachment Process in a Chronological Series of Vegetation Restoration

Science.gov (United States)

Wang, Bing

2017-04-01

The effects of near soil surface characteristics on the soil detachment process might be different at different stages of vegetation restoration. This study was performed to investigate the effects of the near soil surface factors of plant litter, biological soil crusts (BSCs), dead roots and live roots on the soil detachment process by overland flow at different stages of restoration. Soil samples (1 m long, 0.1 m wide, and 0.05 m high) under four treatment conditions were collected from 1-yr-old and 24-yr-old natural grasslands and subjected to flow scouring under five different shear stresses ranging from 5.3 to 14.6 Pa. The results indicated that the effects of near soil surface characteristics on soil detachment were substantial during the process of vegetation restoration. The total reduction in the soil detachment capacity of the 1-yr-old grassland was 98.1%, and of this total, 7.9%, 30.0% and 60.2% was attributed to the litter, BSCs and plant roots, respectively. In the 24-yr-old grassland, the soil detachment capacity decreased by 99.0%, of which 13.2%, 23.5% and 62.3% was caused by the litter, BSCs and plant roots, respectively. Combined with the previously published data of a 7-yr-old grassland, the influence of plant litter on soil detachment was demonstrated to increase with restoration time, but soil detachment was also affected by the litter type and composition. The role of BSCs was greater than that of plant litter in reducing soil detachment during the early stages of vegetation recovery. However, its contribution weakened with time since restoration. The influence of plant roots accounted for at least half or up to two-thirds of the total near soil surface factors, of which more than 72.6% was attributed to the physical binding effects of the roots. The chemical bonding effect of the roots increased with time since restoration and was greater than the effect of the litter on soil detachment in the late stages of vegetation restoration. The

The Role of an Electric Field in the Formation of a Detached Regime in Tokamak Plasma

Science.gov (United States)

Senichenkov, I.; Kaveeva, E.; Rozhansky, V.; Sytova, E.; Veselova, I.; Voskoboynikov, S.; Coster, D.

2018-03-01

Modeling of the transition to the detachment of ASDEX Upgrade tokamak plasma with increasing density is performed using the SOLPS-ITER numerical code with a self-consistent account of drifts and currents. Their role in plasma redistribution both in the confinement region and in the scrape-off layer (SOL) is investigated. The mechanism of high field side high-density formation in the SOL in the course of detachment is suggested. In the full detachment regime, when the cold plasma region expands above the X-point and reaches closed magnetic-flux surfaces, plasma perturbation in a confined region may lead to a change in the confinement regime.

A study on flow development in an APU-style inlet and its effect on centrifugal compressor performance

Science.gov (United States)

Lou, Fangyuan

The objectives of this research were to investigate the flow development inside an APU-style inlet and its effect on centrifugal compressor performance. The motivation arises from the increased applications of gas turbine engines installed with APU-style inlets such as unmanned aerial vehicles, auxiliary power units, and helicopters. The inlet swirl distortion created from these complicated inlet systems has become a major performance and operability concern. To improve the integration between the APU-style inlet and gas turbine engines, better understanding of the flow field in the APU-style inlet and its effect on gas turbine is necessary. A research facility for the purpose of performing an experimental investigation of the flow field inside an APU-style inlet was developed. A subcritical air ejector is used to continuously flow the inlet at desired corrected mass flow rates. The facility is capable of flowing the APU inlet over a wide range of corrected mass flow rate that matches the same Mach numbers as engine operating conditions. Additionally, improvement in the system operational steadiness was achieved by tuning the pressure controller using a PID control method and utilizing multi-layer screens downstream of the APU inlet. Less than 1% relative unsteadiness was achieved for full range operation. The flow field inside the rectangular-sectioned 90? bend of the APU-style inlet was measured using a 3-Component LDV system. The structures for both primary flow and the secondary flow inside the bend were resolved. Additionally, the effect of upstream geometry on the flow development in the downstream bend was also investigated. Furthermore, a Single Stage Centrifugal Compressor research facility was developed at Purdue University in collaboration with Honeywell to operate the APU-style inlet at engine conditions with a compressor. To operate the facility, extensive infrastructure for facility health monitoring and performance control (including lubrication

Effect of flow rate distribution at the inlet on hydrodynamic mixing in narrow rectangular multi-channel

International Nuclear Information System (INIS)

Xu Jianjun; Chen Bingde; Wang Xiaojun

2008-01-01

Flow and heat transfer in the narrow rectangular multi-channel is widely en- countered in the engineering application, hydrodynamic mixing in the narrow rectangular multi-channel is one of the important concerns. With the help of the Computational Fluid Dynamics code CFX, the effect of flow rate distribution of the main channel at the inlet on hydrodynamic mixing in the narrow rectangular multi-channel is numerical simulated. The results show that the flow rate distributions at the inlet have a great effect on hydrodynamics mixing in multi-channel, the flow rate in the main channel doesn't change with increasing the axial mixing section when the average flow rate at the inlet is set. Hydrodynamic mixing will arise in the mixing section when the different ratio of the flow rate distribution at the inlet is set, and hydrodynamic mixing increases with the difference of the flow rate distribution at the inlet increase. The trend of the flow rate distribution of the main channel is consistent during the whole axial mixing section, and hydrodynamic mixing in former 4 mixing section is obvious. (authors)

Fundus autofluorescence findings in a mouse model of retinal detachment.

Science.gov (United States)

Secondi, Roberta; Kong, Jian; Blonska, Anna M; Staurenghi, Giovanni; Sparrow, Janet R

2012-08-07

Fundus autofluorescence (fundus AF) changes were monitored in a mouse model of retinal detachment (RD). RD was induced by transscleral injection of hyaluronic acid (Healon) or sterile balanced salt solution (BSS) into the subretinal space of 4-5-day-old albino Abca4 null mutant and Abca4 wild-type mice. Images acquired by confocal scanning laser ophthalmoscopy (Spectralis HRA) were correlated with spectral domain optical coherence tomography (SD-OCT), infrared reflectance (IR), fluorescence spectroscopy, and histologic analysis. Results. In the area of detached retina, multiple hyperreflective spots in IR images corresponded to punctate areas of intense autofluorescence visible in fundus AF mode. The puncta exhibited changes in fluorescence intensity with time. SD-OCT disclosed undulations of the neural retina and hyperreflectivity of the photoreceptor layer that likely corresponded to histologically visible photoreceptor cell rosettes. Fluorescence emission spectra generated using flat-mounted retina, and 488 and 561 nm excitation, were similar to that of RPE lipofuscin. With increased excitation wavelength, the emission maximum shifted towards longer wavelengths, a characteristic typical of fundus autofluorescence. In detached retinas, hyper-autofluorescent spots appeared to originate from photoreceptor outer segments that were arranged within retinal folds and rosettes. Consistent with this interpretation is the finding that the autofluorescence was spectroscopically similar to the bisretinoids that constitute RPE lipofuscin. Under the conditions of a RD, abnormal autofluorescence may arise from excessive production of bisretinoid by impaired photoreceptor cells.

Primary 25-gauge transconjunctival sutureless vitrectomy in pseudophakic retinal detachment

Directory of Open Access Journals (Sweden)

Horozoglu Fatih

2007-01-01

Full Text Available Aims: There are few reports on 25-gauge transconjunctival sutureless vitrectomy (TSV in cases of pseudophakic retinal detachment. We conducted this study to report the anatomic and functional outcomes of 25-gauge TSV in the treatment of primary pseudophakic retinal detachment (RD. Design: Prospective, interventional case series. Materials and Methods: Fifteen eyes of 15 patients with RD after cataract surgery with phacoemulsification were evaluated. Primary pseudophakic RDs with macular detachment and proliferative vitreoretinopathy Stage B or less were included in the study. Pars plana vitrectomy with the 25-gauge TSV system, perfluorocarbon liquid injection followed by air exchange, endolaser photocoagulation and sulfur hexafluoride gas (20% injection were applied to all eyes. Results: Mean follow-up time was 9.2 months (range, six to 12 months. Retinal reattachment with a single operation was achieved in 93% of eyes and with additional surgery, the retina was reattached in 100% of eyes. Preoperative visual acuity was less than 20/200 in all eyes (range, hand motions to 20/400. Postoperative visual acuity was 20/40 or better in eight eyes (53% and between 20/50 and 20/200 in seven eyes (47%. No severe hypotony was encountered and no sutures were required to close the scleral and conjunctival openings. Postoperative complications were macular pucker in one eye (7% and cystoid macular edema in another eye (7%. Conclusions: Primary 25-gauge TSV system appears to be an effective and safe procedure in the treatment of uncomplicated pseudophakic RD.

Characterisation and airborne deployment of a new counterflow virtual impactor inlet

Directory of Open Access Journals (Sweden)

T. Shingler

2012-06-01

Full Text Available A new counterflow virtual impactor (CVI inlet is introduced with details of its design, laboratory characterisation tests and deployment on an aircraft during the 2011 Eastern Pacific Emitted Aerosol Cloud Experiment (E-PEACE. The CVI inlet addresses three key issues in previous designs; in particular, the inlet operates with: (i negligible organic contamination; (ii a significant sample flow rate to downstream instruments (∼15 l min⁻¹ that reduces the need for dilution; and (iii a high level of accessibility to the probe interior for cleaning. Wind tunnel experiments characterised the cut size of sampled droplets and the particle size-dependent transmission efficiency in various parts of the probe. For a range of counter-flow rates and air velocities, the measured cut size was between 8.7–13.1 μm. The mean percentage error between cut size measurements and predictions from aerodynamic drag theory is 1.7%. The CVI was deployed on the Center for Interdisciplinary Remotely Piloted Aircraft Studies (CIRPAS Twin Otter for thirty flights during E-PEACE to study aerosol-cloud-radiation interactions off the central coast of California in July and August 2011. Results are reported to assess the performance of the inlet including comparisons of particle number concentration downstream of the CVI and cloud drop number concentration measured by two independent aircraft probes. Measurements downstream of the CVI are also examined from one representative case flight coordinated with shipboard-emitted smoke that was intercepted in cloud by the Twin Otter.

Outcome of surgery after macula-off retinal detachment - results from MUSTARD, one of the largest databases on buckling surgery in Europe.

Science.gov (United States)

Thelen, Ulrich; Amler, Susanne; Osada, Nani; Gerding, Heinrich

2012-08-01

To evaluate the anatomical success rate of scleral buckling surgery in the treatment of rhegmatogenous retinal detachment and to evaluate the differences in outcome between patients suffering macula-off retinal detachment and those without a macular involvement. As a retrospective interventional case series, Munster Study on Therapy Achievements in Retinal Detachment (MUSTARD) is one of the largest ever established of retinal detachment patients and their outcome after buckling surgery, with 4325 patients who underwent surgery between 1980 and 2001. In 53.94% (n = 2134) of 3956 patients with nontraumatic retinal detachment, the macula was involved. The main outcome measure was the achievement of dry anatomical attachment of the retina. The success rate in patients with macula-off retinal detachment is 80.46% and thus 7.78% lower (p macula intact whose success rate amounted to 88.24%. The overall success rate of all 4325 MUSTARD patients was 83.98%. Scleral buckling is an established and mostly successful method for the treatment of retinal detachment. As our case series has demonstrated, even eyes with macula-off can be treated successfully by this procedure, thereby avoiding the complications of primary vitrectomy. © 2010 The Authors. Journal compilation © 2010 Acta Ophthalmol.

Effect of inlet conditions on the performance of a palladium membrane reactor

International Nuclear Information System (INIS)

Birdsell, S.A.; Willms, R.S.; Arzu, P.; Costello, A.

1997-10-01

Palladium membrane reactors (PMR) will be used to remove tritium and other hydrogen isotopes from impurities, such as tritiated methane and tritiated water, in the exhaust of the International Thermonuclear Experimental Reactor. In addition to fusion-fuel processing, the PMR system can be used to recover tritium from tritiated waste water. This paper investigates the effect of inlet conditions on the performance of a PMR. A set of experiments were run to determine, independently, the effect of inlet compositions and residence time on performance. Also, the experiments were designed to determine if the injected form of hydrogen (CH 4 or H 2 O) effects performance. Results show that the PMR operates at optimal hydrogen recovery with a broad range of inlet compositions and performance is shown to increase with increased residence time. PMR performance is shown to be independent of whether hydrogen is injected in the form of CH 4 or H 2 O

Rocket-Based Combined Cycle Engine Technology Development: Inlet CFD Validation and Application

Science.gov (United States)

DeBonis, J. R.; Yungster, S.

1996-01-01

A CFD methodology has been developed for inlet analyses of Rocket-Based Combined Cycle (RBCC) Engines. A full Navier-Stokes analysis code, NPARC, was used in conjunction with pre- and post-processing tools to obtain a complete description of the flow field and integrated inlet performance. This methodology was developed and validated using results from a subscale test of the inlet to a RBCC 'Strut-Jet' engine performed in the NASA Lewis 1 x 1 ft. supersonic wind tunnel. Results obtained from this study include analyses at flight Mach numbers of 5 and 6 for super-critical operating conditions. These results showed excellent agreement with experimental data. The analysis tools were also used to obtain pre-test performance and operability predictions for the RBCC demonstrator engine planned for testing in the NASA Lewis Hypersonic Test Facility. This analysis calculated the baseline fuel-off internal force of the engine which is needed to determine the net thrust with fuel on.

Second order tidally induced flow in the inlet of a coastal lagoon

Science.gov (United States)

Eguiluz, Ana; Wong, Kuo-Chuin

2005-08-01

Current meter data obtained in Indian River Inlet and Indian River Bay, Delaware are analyzed to compute second order low-frequency tidal flow and tidally induced mean flow in the system. Results from least-squares harmonic analysis show that nonlinearly induced M4 currents in the inlet and bay occur at order 10 -1 of the M2 amplitudes, indicating weak nonlinearity in the system. Tidally rectified mean flow computed from Mm and Msf is ˜3 cm s -1, which is of the same order of magnitude as the observed mean current. The estimated low-frequency tidal flow and the tidally induced mean flow agree well with scalings computed for the inlet and with results found by Münchow et al. [Münchow, A., Masse, A.K., Garvine, R.W., 1992. Astronomical and nonlinear tidal currents in a coupled estuary shelf system. Continental Shelf Research 12, 471-498] in Delaware Bay.

CFD code calibration and inlet-fairing effects on a 3D hypersonic powered-simulation model

Science.gov (United States)

Huebner, Lawrence D.; Tatum, Kenneth E.

1993-01-01

A three-dimensional (3D) computational study has been performed addressing issues related to the wind tunnel testing of a hypersonic powered-simulation model. The study consisted of three objectives. The first objective was to calibrate a state-of-the-art computational fluid dynamics (CFD) code in its ability to predict hypersonic powered-simulation flows by comparing CFD solutions with experimental surface pressure dam. Aftbody lower surface pressures were well predicted, but lower surface wing pressures were less accurately predicted. The second objective was to determine the 3D effects on the aftbody created by fairing over the inlet; this was accomplished by comparing the CFD solutions of two closed-inlet powered configurations with a flowing-inlet powered configuration. Although results at four freestream Mach numbers indicate that the exhaust plume tends to isolate the aftbody surface from most forebody flowfield differences, a smooth inlet fairing provides the least aftbody force and moment variation compared to a flowing inlet. The final objective was to predict and understand the 3D characteristics of exhaust plume development at selected points on a representative flight path. Results showed a dramatic effect of plume expansion onto the wings as the freestream Mach number and corresponding nozzle pressure ratio are increased.

The Effect of Inlet Waveforms on Computational Hemodynamics of Patient-Specific Intracranial Aneurysms

OpenAIRE

Xiang, J.; Siddiqui, A.H.; Meng, H.

2014-01-01

Due to the lack of patient-specific inlet flow waveform measurements, most computational fluid dynamics (CFD) simulations of intracranial aneurysms usually employ waveforms that are not patient-specific as inlet boundary conditions for the computational model. The current study examined how this assumption affects the predicted hemodynamics in patient-specific aneurysm geometries. We examined wall shear stress (WSS) and oscillatory shear index (OSI), the two most widely studied hemodynamic qu...

OEDGE modeling of DIII-D density scan discharges leading to detachment

Science.gov (United States)

Elder, J. D.; Stangeby, P. C.; Bray, B. D.; Brooks, N.; Leonard, A. W.; McLean, A. G.; Unterberg, E. A.; Watkins, J. G.

2015-08-01

The OEDGE code is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and ADAS hydrogenic emission atomic physics data for Dα, Dβ and Dγ for values of Te and ne characteristic of the range of divertor plasma conditions from attached to weakly detached. Confidence in these values is essential to spectroscopic interpretation of any experiment or modeling effort. Good agreement between experiment and calculated emissions is found for both EIRENE and ADAS calculated emission profiles, confirming their reliability for plasma conditions down to ∼1 eV. For the cold dense plasma conditions characteristic of detachment, it is found that the calculated emissions are especially sensitive to Te.

Complex genetics of familial exudative vitreoretinopathy and related pediatric retinal detachments

Science.gov (United States)

Kondo, Hiroyuki

2015-01-01

Familial exudative vitreoretinopathy (FEVR) is a hereditary vitreoretinal disorder that can cause various types of retinal detachments. The abnormalities in eyes with FEVR are caused by poor vascularization in the peripheral retina. The genetics of FEVR is highly heterogeneous, and mutations in the genes for Wnt signaling and a transcription factor have been reported to be responsible for FEVR. These factors have been shown to be the regulators of the pathophysiological pathways of retinal vascular development. Studies conducted to identify the causative genes of FEVR have uncovered a diverse and complex relationship between FEVR and other diseases; for example, Norrie disease, a Mendelian-inherited disease; retinopathy of prematurity, a multifactorial genetic disease; and Coats disease, a nongenetic disease, associated with pediatric retinal detachments. PMID:29018668

Genetic risk of rhegmatogenous retinal detachment a familial aggregation study

NARCIS (Netherlands)

S.L. Go (Sioe Lie); C. Hoyng (Carel); C.C.W. Klaver (Caroline)

2005-01-01

textabstractObjective: To investigate the magnitude of the genetic risk of nonsyndromic rhegmatogenous retinal detachments (RRDs) in a familial aggregation study. Design: Two hundred three consecutive patients with RRD and 461 controls without RRD were ascertained at the Department of Ophthalmology

Study of Plasma Detachment in a Simplified 2D Geometry using UEDGE

International Nuclear Information System (INIS)

Groth, M; Mahdavi, A M; Porter, G D; Rognlien, T D

2001-01-01

The location of the ionization front in a generic, detached plasma has been studied in a two-dimensional slab geometry by varying the core plasma density and input heating power. The ratio of the recombination to ionization current and the momentum losses in the computational domain have been used to quantify the degree of detachment. Contours of constant ratio of these parameter in the core plasma density--heating power parameter space show that at high input power higher momentum losses can be achieved even at low density. High fraction of recombination, however, require high core densities to sufficiently separate the plasma from the target plate

Surgical management of retinal diseases: proliferative diabetic retinopathy and traction retinal detachment.

Science.gov (United States)

Cruz-Iñigo, Yousef J; Acabá, Luis A; Berrocal, Maria H

2014-01-01

Current indications for pars plana vitrectomy in patients with proliferative diabetic retinopathy (PDR) include vitreous hemorrhage, tractional retinal detachment (TRD), combined tractional and rhegmatogenous retinal detachment (CTRRD), diabetic macular edema associated with posterior hyaloidal traction, and anterior segment neovascularization with media opacities. This chapter will review the indications, surgical objectives, adjunctive pharmacotherapy, microincision surgical techniques, and outcomes of diabetic vitrectomy for PDR, TRD, and CTRRD. With the availability of new microincision vitrectomy technology, wide-angle microscope viewing systems, and pharmacologic agents, vitrectomy can improve visual acuity and achieve long-term anatomic stability in eyes with severe complications from PDR. © 2014 S. Karger AG, Basel

Clinically undetected retinal breaks causing retinal detachment: A review of options for management.

Science.gov (United States)

Gupta, Deepak; Ching, Jared; Tornambe, Paul E

2017-08-12

The successful detection of retinal breaks is a critical step in rhegmatogenous retinal detachment surgery in order to prevent persistent/recurrent retinal detachments. Not all retinal breaks causing retinal detachments are obvious. Retinal breaks may be obscured by opacities that are either anterior segment related, lens related, or posterior segment related. Rules to identify breaks based on subretinal fluid configuration are more difficult to apply in pseudophakic, aphakic, and scleral buckle encircled eyes-and in eyes with repeat detachments and those with proliferative vitreoretinopathy. Exudative detachments exhibit characteristic features and must be ruled out. A thorough clinical examination preoperatively is important even if a vitrectomy is planned. We review the incidence and causes of undetected breaks, along with preoperative/clinical issues that may hinder break detection. We review the literature with respect to investigative approaches and techniques that are available to the vitreoretinal surgeon when primary breaks remain clinically undetected during the preoperative examination. We broadly divide the surgical approaches into ones where the surgeon utilizes techniques to pursue actively a search for breaks versus adopting a purely speculative approach. Advantages and disadvantages of various techniques are appraised. Intuitively one might argue that an encircling scleral buckle combined with vitrectomy would give higher single operation success than pars plana vitrectomy alone because "undetected" retinal breaks would be addressed by a 360° plombage. We could not confirm this concept. Newer techniques, such as pars plana vitrectomy augmented with dye extrusion or endoscopic-assisted pars plana vitrectomy, show encouraging results. Technological advances such as intraoperative optical coherence tomography will also help to broaden the vitreoretinal surgeon's armamentarium. At this time, there is no gold standard in terms of the recommended

The role of energy advisors on adoption of energy efficiency measures in detached houses

Energy Technology Data Exchange (ETDEWEB)

Mahapatra, Krushna; Nair, Gireesh; Gustavsson, Leif [Ecotechnology, Mid Sweden Univ., Oestersund (Sweden)

2009-07-01

External actors can influence potential adopters to adopt energy efficiency measures. In Sweden energy advisers are one such actor group who provides energy advice and information to the end users. Currently, all municipalities offer energy advisers' service. The success of such service for improvement of energy efficiency of detached houses depends on homeowners' perception towards it. In this context we conducted a national survey of about 3000 owners of detached houses through stratified random sampling method in 2008 summer. We found that majority of owners' of detached houses consider energy advisers as an important source of information. Furthermore, many homeowners who contacted energy advisers for advice had implemented the suggestions. However, only a few homeowners had actually contacted energy advisers. Our findings suggest that it is beneficial to continue the energy adviser service, but more efforts are needed to increase homeowners' awareness of and satisfaction with such services.

Ancient Wall Tiles – The Importance of the Glaze/Ceramic Interface in Glaze Detachment

Directory of Open Access Journals (Sweden)

Marisa COSTA

2014-04-01

Full Text Available One of the most severe pathologies suffered by early industrially produced tiles in Portugal in late nineteenth century is glaze detachment in wall tiles placed in the lower part of the façade. It is known that salts crystallize provoking the glaze detachment, destroying the waterproofing and the beauty of the wall tile and this is one of the crucial factors towards this occurrence. The present work questions the importance of the thickness of glaze/ceramic body interface, in what concerns glaze detachment provoked by salt crystallization. SEM-EDS was used to perform all the observations that lead to the conclusion that the exuberance of the interface between glaze and ceramic body has no influence in the resistance of the glaze to salt crystallization though time, being the porous network more determinant. DOI: http://dx.doi.org/10.5755/j01.ms.20.1.3815

FTIR measurements of OH in deformed quartz and feldspars of the South Tibetan Detachment, Greater Himalaya

Science.gov (United States)

Jezek, L.; Law, R. D.; Jessup, M. J.; Searle, M. P.; Kronenberg, A. K.

2017-12-01

OH absorption bands due to water in deformed quartz and feldspar grains of mylonites from the low-angle Lhotse Detachment (of the South Tibetan Detachment System, Rongbuk Valley north of Mount Everest) have been measured by Fourier Transform Infrared (FTIR) Spectroscopy. Previous microstructural studies have shown that these rocks deformed by dislocation creep at high temperature conditions in the middle crust (lower - middle amphibolite facies), and oxygen isotope studies suggest significant influx of meteoric water. OH absorption bands at 3400 cm-1 of quartz mylonites from the footwall of the Lhotse Detachment Fault are large, with the character of the molecular water band due to fluid inclusions in milky quartz. Mean water contents depend on structural position relative to the core of the Lhotse Detachment, from 1000 ppm (OH/106 Si) at 420 m below the fault to 11,350 (+/-1095) ppm near its center. The gradient in OH content shown by quartz grains implies influx of meteoric water along the Lhotse Detachment from the Tibetan Plateau ground surface to middle crustal depths, and significant fluid penetration into the extruding Himalayan slab by intergranular, permeable fluid flow processes. Feldspars of individual samples have comparable water contents to those of quartz and some are wetter. Large water contents of quartz and feldspar may have contributed to continued deformation and strain localization on the South Tibetan Detachment System. Dislocation creep in quartz is facilitated by water in laboratory experiments, and the water contents of the Lhotse fault rocks are similar to (and even larger than) water contents of quartz experimentally deformed during water weakening. Water contents of feldspars are comparable to those of plagioclase aggregates deformed experimentally by dislocation and diffusion creep under wet conditions.

Background-Oriented Schlieren (BOS) for Scramjet Inlet-isolator Investigation

Science.gov (United States)

Che Idris, Azam; Rashdan Saad, Mohd; Hing Lo, Kin; Kontis, Konstantinos

2018-05-01

Background-oriented Schlieren (BOS) technique is a recently invented non-intrusive flow diagnostic method which has yet to be fully explored in its capabilities. In this paper, BOS technique has been applied for investigating the general flow field characteristics inside a generic scramjet inlet-isolator with Mach 5 flow. The difficulty in finding the delicate balance between measurement sensitivity and measurement area image focusing has been demonstrated. The differences between direct cross-correlation (DCC) and Fast Fourier Transform (FFT) raw data processing algorithm have also been demonstrated. As an exploratory study of BOS capability, this paper found that BOS is simple yet robust enough to be used to visualize complex flow in a scramjet inlet in hypersonic flow. However, in this case its quantitative data can be strongly affected by 3-dimensionality thus obscuring the density value with significant errors.

Performance of a high-work low aspect ration turbine tested with a realistic inlet radial temperature profile

Science.gov (United States)

Stabe, R. G.; Whitney, W. J.; Moffitt, T. P.

1984-01-01

Experimental results are presented for a 0.767 scale model of the first stage of a two-stage turbine designed for a high by-pass ratio engine. The turbine was tested with both uniform inlet conditions and with an inlet radial temperature profile simulating engine conditions. The inlet temperature profile was essentially mixed-out in the rotor. There was also substantial underturning of the exit flow at the mean diameter. Both of these effects were attributed to strong secondary flows in the rotor blading. There were no significant differences in the stage performance with either inlet condition when differences in tip clearance were considered. Performance was very close to design intent in both cases.

Collisional-electron detachment of Cl- on diatomic molecules

International Nuclear Information System (INIS)

Annis, B.K.; Datz, S.

1981-01-01

Recent experimental results for collisional-electron detachment of Cl - by H 2 /D 2 , N 2 , O 2 , NO, and CO are discussed. The emphasis is on angular distributions and energy loss measurements for laboratory energies of a few hundred eV. Evidence for the possibility of bound excited states of N 2 Cl and COCl and the role of target negative-ion resonant states is presented

Coming back to work in the morning: Psychological detachment and reattachment as predictors of work engagement.

Science.gov (United States)

Sonnentag, Sabine; Kühnel, Jana

2016-10-01

Research has shown that recovery processes in general and psychological detachment in particular are important for work engagement. We argue that work engagement additionally benefits from reattachment to work in the morning (i.e., mentally reconnecting to work before actually starting to work) and that the gains derived from psychological detachment and reattachment are stronger in the morning than in the afternoon. We tested our hypotheses in a daily diary study with a sample of 167 employees who completed 2 surveys per day over the period of 2 workweeks. Hierarchical linear modeling showed that work engagement was higher in the morning than in the afternoon. Evening psychological detachment and morning reattachment positively predicted work engagement throughout the day. The association between reattachment and work engagement was stronger in the morning than in the afternoon. This study demonstrates that not only psychological detachment from work during leisure time, but also reattachment to work when coming back to work are crucial for daily engagement at work. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Microperimetry and optical coherent tomography in patients operated on y the conventional retinal detachment surgery

International Nuclear Information System (INIS)

Guerra Garcia, Roberto Alejandro; Rodriguez Rodriguez, Beatriz N; Eguia Martinez, Frank

2008-01-01

A descriptive study was made to determine the visual acuity, microperimetry and optical coherence tomography in patients operated on by the conventional rhegmatogenous retinal detachment at 'Ramon Pando Ferrer' Cuban Ophthalmologic Institute from October 2006 to March 2007. Twenty six patients, who had gone to the hospital with normal values in ophthalmoscopy and biomicroscopy and three-six months of disease development. Better corrected visual acuity, fixation, average sensitivity, morphology and macular thickness were obtained after surgery. Average visual acuity was 0,41 and fixation was stable in most of patients; average retinal sensitivity was 11 decibels. The most frequent finding was serum detachment. Average macular thickness was 246,3 micras. There was no statistical relation between preoperative time of disease development and the macular characteristics of detachment in these tests. (Author)

Long-Term Ecological Research (LTER) Climate Data with Water Parameters from North Inlet Meteorological Station, North Inlet Estuary, Georgetown, South Carolina: 1982-1996.

Data.gov (United States)

Baruch Institute for Marine and Coastal Sciences, Univ of South Carolina — Meteorological data with water parameters were collected on an hourly basis from June 3, 1982 through April 29, 1996 in the North Inlet Estuary, Georgetown County,...

INTERNAL LIMITING MEMBRANE PEELING-DEPENDENT RETINAL STRUCTURAL CHANGES AFTER VITRECTOMY IN RHEGMATOGENOUS RETINAL DETACHMENT.

Science.gov (United States)

Hisatomi, Toshio; Tachibana, Takashi; Notomi, Shoji; Koyanagi, Yoshito; Murakami, Yusuke; Takeda, Atsunobu; Ikeda, Yasuhiro; Yoshida, Shigeo; Enaida, Hiroshi; Murata, Toshinori; Sakamoto, Taiji; Sonoda, Koh-Hei; Ishibashi, Tatsuro

2018-03-01

To examine retinal changes after vitrectomy with internal limiting membrane (ILM) peeling, we used 3-dimensional optical coherence tomography (3D-OCT) in rhegmatogenous retinal detachment cases. The 68 eyes from 67 patients with rhegmatogenous retinal detachment were studied, including 35 detached macula cases (51%) and 33 attached macula cases. Internal limiting membrane peeling was performed with fine forceps after brilliant blue G staining. The 3D-OCT images were obtained with volume-rendering technologies from cross-sectional OCT images. The 3D-OCT detected 45 eyes (66%) with ILM peeling-dependent retinal changes, including dissociated optic nerve fiber layer appearance, dimple sign, temporal macular thinning, ILM peeling area thinning, or forceps-related retinal thinning. The ILM peeled area was detectable in only 9 eyes with 3D-OCT, whereas it was undetectable in other 59 eyes. The dissociated optic nerve fiber layer appearance was detected in 8 of the total cases (12%), and dimple signs were observed in 14 cases (21%). Forceps-related thinning was also noted in eight cases (24%) of attached macula cases and in four cases (11%) of detached macula cases. No postoperative macular pucker was noted in the observational period. The 3D-OCT clearly revealed spatial and time-dependent retinal changes after ILM peeling. The changes occurred in 2 months and remained thereafter.

[Photosynthetic characteristics of Cuscuta japonica and its hosts during parasitization and after detachment].

Science.gov (United States)

Wang, Dong; Hu, Fei; Chen, Yu-Fen; Yang, Jun; Kong, Chui-Hua

2007-08-01

The study on the photosynthetic characteristics of Cuscuta japonica and its hosts showed that there was a negative correlation between the photosynthetic pigment content (PPC) of C. japonica and its hosts. The PPC increased in the C. japonica-preferred hosts' parasitized and neighboring leaves, but decreased in its less preferred hosts' parasitized and neighboring leaves. The leaves parasitized by C. japonica and their neighboring far from the parasitized ones had a lowered net photosynthesis rate P(n), and the decreasing order accorded with that of parasitization. The decrease of P(n) for C. japonica-less preferred hosts was mainly due to the stomatal factors, but that for the preferred hosts was regulated by multi-factors. Under light, the PPC of C. japonica detached from preferred hosts increased faster than that of C. japonica detached from less preferred hosts, but the dry matter decrease was in adverse. In dark, however, the changes in PPC and dry matter content of C. japonica were not significant, whatever hosts it was detached from.

Epithelial cell detachment by Porphyromonas gingivalis biofilm and planktonic cultures

NARCIS (Netherlands)

Huang, L.; van Loveren, C.; Ling, J.; Wei, X.; Crielaard, W.; Deng, D.M.

2016-01-01

Porphyromonas gingivalis is present as a biofilm at the sites of periodontal infections. The detachment of gingival epithelial cells induced by P. gingivalis biofilms was examined using planktonic cultures as a comparison. Exponentially grown planktonic cultures or 40-h biofilms were co-incubated

Measurement of the relative afferent pupillary defect in retinal detachment.

Science.gov (United States)

Bovino, J A; Burton, T C

1980-07-01

A swinging flashlight test and calibrated neutral density filters were used to quantitate the depth of relative afferent pupillary defects in ten patients with retinal detachment. Postoperatively, the pupillary responses returned to normal in seven of nine patients with anatomically successful surgery.

Genetic risk of rhegmatogenous retinal detachment: a familial aggregation study.

NARCIS (Netherlands)

Go, S.L.; Hoyng, C.B.; Klaver, C.C.W.

2005-01-01

OBJECTIVE: To investigate the magnitude of the genetic risk of nonsyndromic rhegmatogenous retinal detachments (RRDs) in a familial aggregation study. DESIGN: Two hundred three consecutive patients with RRD and 461 controls without RRD were ascertained at the Department of Ophthalmology of the

Feasibility of Shape-Memory Ni/Ti Alloy Wire Containing Tube Elevators for Transcrestal Detaching Maxillary Sinus Mucosa: Ex Vivo Study

Directory of Open Access Journals (Sweden)

Yanfeng Li

2016-12-01

Full Text Available Background: Osteotome sinus floor elevation is a less invasive approach to augment an insufficient alveolar bone at the posterior maxilla for dental implantation. However, this approach has some limitations due to the lack of sinus lift tools available for clinical use and the small transcrestal access to the maxillary sinus floor. We recently invented shape-memory Ni/Ti alloy wire containing tube elevators for transcrestal detaching maxillary sinus mucosa, and developed goat ex vivo models for direct visualizing the effectiveness of detaching sinus mucosa in real time during transcrestal maxillary sinus floor elevation. Methods: We evaluated our invented elevators, namely elevator 012 and elevator 014, for their effectiveness for transcrestal detaching maxillary sinus mucosa using the goat ex vivo models. We measured the length of sinus mucosa detached in mesial and distal directions or buccal and palatal directions, and the space volume created by detaching maxillary sinus mucosa in mesial, distal, buccal and palatal directions using the invented elevators. Results: Elevator 012 had a shape-memory Ni/Ti alloy wire with a diameter of 0.012 inch, while elevator 014 had its shape-memory Ni/Ti alloy wire with a diameter of 0.014 inch. Elevator 012 could detach the goat maxillary sinus mucosa in the mesial or distal direction for 12.1±4.3 mm, while in the buccal or palatal direction for 12.5±6.7 mm. The elevator 014 could detach the goat maxillary sinus mucosa for 23.0±4.9 mm in the mesial or distal direction, and for 19.0±8.1 mm in the buccal or palatal direction. An average space volume of 1.7936±0.2079 ml was created after detaching the goat maxillay sinus mucosa in both mesial/distal direction and buccal/palatal direction using elevator 012; while the average space volume created using elevator 014 was 1.8764±0.2366 ml. Conclusion: Both two newly invented tube elevators could effectively detach the maxillary sinus mucosa on the goat ex

Feasibility of Shape-Memory Ni/Ti Alloy Wire Containing Tube Elevators for Transcrestal Detaching Maxillary Sinus Mucosa: Ex Vivo Study.

Science.gov (United States)

Li, Yanfeng; Wang, Fuli; Hu, Pin; Fan, Jiadong; Han, Yishi; Liu, Bin; Liu, Tao; Yang, Chunhao; Gu, Xiangmin

2016-01-01

Osteotome sinus floor elevation is a less invasive approach to augment an insufficient alveolar bone at the posterior maxilla for dental implantation. However, this approach has some limitations due to the lack of sinus lift tools available for clinical use and the small transcrestal access to the maxillary sinus floor. We recently invented shape-memory Ni/Ti alloy wire containing tube elevators for transcrestal detaching maxillary sinus mucosa, and developed goat ex vivo models for direct visualizing the effectiveness of detaching sinus mucosa in real time during transcrestal maxillary sinus floor elevation. We evaluated our invented elevators, namely elevator 012 and elevator 014, for their effectiveness for transcrestal detaching maxillary sinus mucosa using the goat ex vivo models. We measured the length of sinus mucosa detached in mesial and distal directions or buccal and palatal directions, and the space volume created by detaching maxillary sinus mucosa in mesial, distal, buccal and palatal directions using the invented elevators. Elevator 012 had a shape-memory Ni/Ti alloy wire with a diameter of 0.012 inch, while elevator 014 had its shape-memory Ni/Ti alloy wire with a diameter of 0.014 inch. Elevator 012 could detach the goat maxillary sinus mucosa in the mesial or distal direction for 12.1±4.3 mm, while in the buccal or palatal direction for 12.5±6.7 mm. The elevator 014 could detach the goat maxillary sinus mucosa for 23.0±4.9 mm in the mesial or distal direction, and for 19.0±8.1 mm in the buccal or palatal direction. An average space volume of 1.7936±0.2079 ml was created after detaching the goat maxillay sinus mucosa in both mesial/distal direction and buccal/palatal direction using elevator 012; while the average space volume created using elevator 014 was 1.8764±0.2366 ml. Both two newly invented tube elevators could effectively detach the maxillary sinus mucosa on the goat ex vivo sinus models. Moreover, elevator 014 has advantages over

Daily impaired detachment and short-term effects of impaired sleep quality on next-day commuting near-accidents - an ambulatory diary study.

Science.gov (United States)

Pereira, Diana; Bucher, Sarah; Elfering, Achim

2016-08-01

This study investigated the short-term effects of daily recovery, that is, impaired psychological detachment from work and various actigraphical indicators of sleep quality, on near-accidents when commuting to work the next morning. Furthermore, the mediating effect of actigraphically assessed sleep quality on the relationship between impaired psychological detachment from work and near-accidents when commuting to work was analysed. Fifty-six full-time employees of a Swiss assurance company participated in the one-week study. Multilevel analyses revealed that impaired detachment was highly related to a decrease in sleep duration. Furthermore, impaired daily recovery processes, such as impaired psychological detachment from work and disturbed sleep quality, were related to commuting near-accidents. Impaired sleep quality mediated the effect of impaired psychological detachment from work on these near-accidents. Our results show that occupational safety interventions should address both impaired psychological detachment from work and sleep quality in order to prevent near accidents when commuting to work. Practitioner Summary: Commuting accidents occur frequently and have detrimental effects on employees, organisations and society. This study shows that daily lack of recovery, that is, impaired psychological detachment and impaired sleep quality, is related to near-accidents when commuting to work the next morning. Primary prevention of commuting accidents should therefore address daily lack of recovery.

[Internal limiting membrane peeling as prophylaxis of epimacular membrane formation in eyes undergoing vitrectomy for rhegmatogenous retinal detachement].

Science.gov (United States)

Hejsek, L; Dusová, J; Stepanov, A; Rozsíval, P

2014-06-01

Rhegmatogenous retinal detachment is a serious condition that can significantly impair visual function, even after a successful surgery. One of the complications that can significantly impair visual acuity in the postoperative period is a development of the epimacular membrane (ERM). The aim of this work is to monitor the effect of peeling of the internal limiting membrane (ILM) in the macula at the anatomical and functional results in the postoperative period, especially with regard to the development of ERM. Prospective study of 21 eyes, which underwent peeling of ILM during pars plana vitrectomy for rhegmatogenous retinal detachment (on detached macula). The ILM peeling was done without using decalin during this procedure. We tested best corrected visual acuity (BCVA) and followed fundus biomicroscopic findings. Proliferative vitreoretinopathy (PVR) was evaluated according to the recommendations of the Retina Society Terminology Committee. To exclude the development of ERM in the macula optical coherence tomography (OCT) was performed at the end of the 18-month follow-up period. In total, the results of 21 eyes of 21 patients who underwent PPV for rhegmatogenous retinal detachment were evaluated. In all of them was during PPV performed ILM peeling on detached macula, these are followed prospectively. ILM peeling without using decalin was sufficient in all eyes. All eyes with ILM peeling did not develop ERM at the end of the follow-up period. ILM peeling during PPV for rhegmatogenous retinal detachment reduces the risk of developing secondary ERM.

Giant High-Flow Type Pulmonary Arteriovenous Malformation: Coil Embolization with Flow Control by Balloon Occlusion and an Anchored Detachable Coil

International Nuclear Information System (INIS)

Kanematsu, Masayuki; Kondo, Hiroshi; Goshima, Satoshi; Tsuge, Yusuke; Watanabe, Haruo; Moriyama, Noriyuki

2012-01-01

Pulmonary arteriovenous malformations (PAVMs) are often treated by pushable fibered or non-fibered microcoils, using an anchor or scaffold technique or with an Amplatzer plug through a guiding sheath. When performing percutaneous transcatheter microcoil embolization, there is a risk of coil migration, particularly with high-flow type PAVMs. The authors report on a unique treatment in a patient with a giant high-flow PAVM whose nidus had a maximum diameter of 6 cm. A detachable coil, not detached from a delivery wire (an anchored detachable coil), was first placed in the feeding artery under flow control by balloon occlusion, and then multiple microcoils were packed proximally to the anchored detachable coil. After confirming the stability of the microcoils during a gradual deflation of the balloon, we finally released the first detachable coil. The nidus was reduced in size to 15 mm at one year postoperatively.

Modeling of combined effects of divertor closure and advanced magnetic configuration on detachment in DIII-D by SOLPS

Science.gov (United States)

Si, H.; Guo, H. Y.; Covele, B.; Leonard, A. W.; Watkins, J. G.; Thomas, D.; Ding, R.

2018-05-01

One of the major challenges facing the design and operation of next-step high-power steady-state fusion devices is to develop a divertor solution for handling power exhaust, while ensuring acceptable divertor target plate erosion, which necessitates access to divertor detachment at relative low main plasma densities compatible with current drive and high plasma confinement. Detailed modeling with SOLPS is carried out to examine the effect of divertor closure on detachment with the normal single null divertor (SD) configuration, as well as one of the advanced divertor configurations, such as x-divertor (XD) respectively. The SOLPS modeling for a high confinement plasma in DIII-D finds that increasing divertor closure with SD reduces the upstream separatrix density at the onset of detachment from 1.18× {{10}19} {{m}-3} to 0.88× {{10}19} {{m}-3} . Moreover, coupling the divertor closure with XD further promotes the onset of divertor detachment at a still lower upstream separatrix density, down to the value of 0.67× {{10}19} {{m}-3} , thus, showing that divertor closure and advanced magnetic configuration can work synergistically to facilitate divertor detachment.

An Analysis of Microbial Pollution in the Sinclair-Dyes Inlet Watershed

Energy Technology Data Exchange (ETDEWEB)

May, Christopher W.; Cullinan, Valerie I.

2005-09-21

This assessment of fecal coliform sources and pathways in Sinclair and Dyes Inlets is part of the Project ENVironmental InVESTment (ENVVEST) being conducted by the Navy's Puget Sound Naval Shipyard and Intermediate Maintenance Facility in cooperation with the US Environmental Protection Agency, Washington State Department of Ecology, the Suquamish Tribe, Kitsap County, the City of Bremerton, the City of Port Orchard, and other local stakeholders. The goal of this study was to identify microbial pollution problems within the Sinclair-Dyes Inlet watershed and to provide a comprehensive assessment of fecal coliform (FC) contamination from all identifiable sources in the watershed. This study quantifies levels of contamination and estimated loadings from known sources within the watersheds and describes pollutant transport mechanisms found in the study area. In addition, the effectiveness of pollution prevention and mitigation measures currently in place within the Sinclair-Dyes Inlet watershed are discussed. This comprehensive study relies on historical data collected by several cooperating agencies, in addition to data collected during the study period from spring 2001 through summer 2005. This report is intended to provide the technical information needed to continue current water quality cleanup efforts and to help implement future efforts.

Primary Repair of Moderate Severity Rhegmatogenous Retinal Detachment: A Critical Decision-Making Algorithm.

Science.gov (United States)

Velez-Montoya, Raul; Jacobo-Oceguera, Paola; Flores-Preciado, Javier; Dalma-Weiszhausz, Jose; Guerrero-Naranjo, Jose; Salcedo-Villanueva, Guillermo; Garcia-Aguirre, Gerardo; Fromow-Guerra, Jans; Morales-Canton, Virgilio

2016-01-01

We reviewed all the available data regarding the current management of non-complex rhegmatogenous retinal detachment and aimed to propose a new decision-making algorithm aimed to improve the single surgery success rate for mid-severity rhegmatogenous retinal detachment. An online review of the Pubmed database was performed. We searched for all available manuscripts about the anatomical and functional outcomes after the surgical management, by either scleral buckle or primary pars plana vitrectomy, of retinal detachment. The search was limited to articles published from January 1995 to December 2015. All articles obtained from the search were carefully screened and their references were manually reviewed for additional relevant data. Our search specifically focused on preoperative clinical data that were associated with the surgical outcomes. After categorizing the available data according to their level of evidence, with randomized-controlled clinical trials as the highest possible level of evidence, followed by retrospective studies, and retrospective case series as the lowest level of evidence, we proceeded to design a logical decision-making algorithm, enhanced by our experiences as retinal surgeons. A total of 7 randomized-controlled clinical trials, 19 retrospective studies, and 9 case series were considered. Additional articles were also included in order to support the observations further. Rhegmatogenous retinal detachment is a potentially blinding disorder. Its surgical management seems to depend more on a surgeon´s preference than solid scientific data or is based on a good clinical history and examination. The algorithms proposed herein strive to offer a more rational approach to improve both anatomical and functional outcomes after the first surgery.

EARLY SIMULTANEOUS FUNDUS AUTOFLUORESCENCE AND OPTICAL COHERENCE TOMOGRAPHY FEATURES AFTER PARS PLANA VITRECTOMY FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT

NARCIS (Netherlands)

Dellʼomo, Roberto; Mura, Marco; Lesnik Oberstein, Sarit Y.; Bijl, Heico; Tan, H. Stevie

2012-01-01

Purpose: To describe fundus autofluorescence and optical coherence tomography (OCT) features of the macula after pars plana vitrectomy for rhegmatogenous retinal detachment. Methods: Thirty-three eyes of 33 consecutive patients with repaired rhegmatogenous retinal detachment with or without the

Experimental Investigation of a Hypersonic Inlet with Variable Sidewall for Flow Control

Science.gov (United States)

Rolim, T. C.; Lu, F. K.

The main function of a scramjet inlet is to decelerate and compress the air for subsequent reaction with the fuel inside the combustor and, of course, contribute toward meeting the thrust requirement for the entire mission by providing adequate mass flow. It is desirable that the inlet be lightweight and that its geometry be capable of producing a uniform flow in an appropriate state to permit efficient mixing and subsequent combustion. Engine cycle analysis indicates that high contraction ratios CR are desirable for achieving high overall engine efficiency.

Performance of a high-work low aspect ratio turbine tested with a realistic inlet radial temperature profile

Science.gov (United States)

Stabe, R. G.; Whitney, W. J.; Moffitt, T. P.

1984-01-01

Experimental results are presented for a 0.767 scale model of the first stage of a two-stage turbine designed for a high by-pass ratio engine. The turbine was tested with both uniform inlet conditions and with an inlet radial temperature profile simulating engine conditions. The inlet temperature profile was essentially mixed-out in the rotor. There was also substantial underturning of the exit flow at the mean diameter. Both of these effects were attributed to strong secondary flows in the rotor blading. There were no significant differences in the stage performance with either inlet condition when differences in tip clearance were considered. Performance was very close to design intent in both cases. Previously announced in STAR as N84-24589

A SECOND CASE OF BILATERAL RHEGMATOGENOUS RETINAL DETACHMENTS REPAIRED WITH SIMULTANEOUS BILATERAL PNEUMATIC RETINOPEXY.

Science.gov (United States)

Rubin, Uriel; De Jager, Cornelis; Zakour, Moayed; Gonder, J Thomas

2017-01-01

To present a case of a patient with simultaneous bilateral retinal detachments treated successfully with bilateral pneumatic retinopexy. Case report. This is a case of an otherwise healthy 49-year-old woman with no remarkable ocular history that presented with simultaneous phakic superior bilateral rhegmatogenous retinal detachments. Treatment on the day of presentation included laser retinopexy of the inferior lattice degeneration in the left eye and bilateral intravitreal injection of 0.4 cc of 100% C3F8 gas preceded by topical anesthesia. After 48 hours, both retinas were completely reattached, and bilateral laser retinopexy was performed to the superior tears. After a review of the literature, the authors could find only two reported cases of simultaneous bilateral retinal detachments treated successfully with pneumatic retinopexy. This is not only a cost-effective procedure but also allows treatment when there is no immediate operating room availability or a when a quick referral for surgery is not possible.

OEDGE modeling of DIII-D density scan discharges leading to detachment

Energy Technology Data Exchange (ETDEWEB)

Elder, J.D., E-mail: david@starfire.utias.utoronto.ca [University of Toronto Institute for Aerospace Studies, Toronto M3H 5T6 (Canada); Stangeby, P.C. [University of Toronto Institute for Aerospace Studies, Toronto M3H 5T6 (Canada); General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Bray, B.D. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Brooks, N. [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94550 (United States); Leonard, A.W. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); McLean, A.G. [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94550 (United States); Unterberg, E.A. [Oak Ridge National Laboratories, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Watkins, J.G. [Sandia National Laboratories, PO Box 5800, Albuquerque, NM 87185 (United States)

2015-08-15

The OEDGE code is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and ADAS hydrogenic emission atomic physics data for D{sub α}, D{sub β} and D{sub γ} for values of T{sub e} and n{sub e} characteristic of the range of divertor plasma conditions from attached to weakly detached. Confidence in these values is essential to spectroscopic interpretation of any experiment or modeling effort. Good agreement between experiment and calculated emissions is found for both EIRENE and ADAS calculated emission profiles, confirming their reliability for plasma conditions down to ∼1 eV. For the cold dense plasma conditions characteristic of detachment, it is found that the calculated emissions are especially sensitive to T{sub e}.

Detached-eddy simulation of flow around the NREL phase VI blade

DEFF Research Database (Denmark)

Johansen, Jeppe; Sørensen, Niels N.; Michelsen, J.A.

2002-01-01

the blade axis. Computed blade characteristics are compared with experimental data from the NREL/NASA Ames Phase VI unsteady experiment. The detached-eddy simulation model is a method for predicting turbulence in computational fluid dynamics computations, which combines a Reynolds-averaged Navier......-eddy simulation show considerably more three-dimensional flow structures compared to conventional two-equation Reynolds-averaged Navier–Stokes turbulence models, but no particular improvements are seen in the global blade characteristics. Copyright © 2002 John Wiley & Sons, Ltd.......The detached-eddy simulation model implemented in the computational fluid dynamics code EllipSys3D is used to calculate the flow around the non-rotating NREL Phase VI wind turbine blade. Results are presented for flow around a parked blade at fixed angle of attack and a blade pitching along...

Correlates of interpersonal dependency and detachment in an adolescent inpatient sample.

Science.gov (United States)

Haggerty, Greg; Siefert, Caleb J; Bornstein, Robert F; Sinclair, Samuel Justin; Blais, Mark A; Zodan, Jennifer; Rao, Nyapati

2015-01-01

Interpersonal dependency has been linked to psychological distress, depression, help seeking, treatment compliance, and sensitivity to interpersonal cues in adult samples. However, there is a dearth of research focusing on dependency in child and adolescent samples. The current study examined the construct validity of a measure of interpersonal dependency. The authors investigated how interpersonal dependency and detachment relate to behavioral problems, subjective well-being, interpersonal problems, and global symptom severity in adolescent inpatients. Destructive overdependence (DO) and dysfunctional detachment (DD) were positively related to interpersonal distress, behavioral problems, and symptom severity and negatively related to psychological health and well-being. Healthy dependency (HD) was associated with fewer behavioral problems and less symptom severity and positively related to subjective well-being. The clinical implications of these findings are discussed.

Reconstitutable control assembly having removable control rods with detachable split upper end plugs

International Nuclear Information System (INIS)

Gjertsen, R.K.; Knott, R.P.; Sparrow, J.A.

1989-01-01

This patent describes, in a reconstitutable control assembly for use with a nuclear fuel assembly, the control assembly including a spider structure and at least one control rod, an attachment joint for detachable fastening the control rod to the spider structure. The attachment joint comprising: a hollow connecting finger on the spider structure; and an elongated detachable split upper end plug on the control rod having a pair of separate upper and lower plug portions, the upper plug portion having integrally-connected tandemly- arranged upper, middle and lower sections. The lower plug portion having integrally-connected tandemly-arranged upper, middle and lower segments

Changes in Retinal Function and Cellular Remodeling Following Experimental Retinal Detachment in a Rabbit Model

Directory of Open Access Journals (Sweden)

Tilda Barliya

2017-01-01

Full Text Available Purpose. To explore functional electroretinographic (ERG changes and associated cellular remodeling following experimental retinal detachment in a rabbit model. Methods. Retinal detachment was created in ten rabbits by injecting 0.1 ml balanced salt solution under the retina. Fundus imaging was performed 0, 3, 7, 14, and 21 days postoperatively. ERGs were recorded pre- and 7 and 21 days postoperatively. Eyes were harvested on day 21 and evaluated immunohistochemically (IHC for remodeling of second- and third-order neurons. Results. Retinal reattachment occurred within two weeks following surgery. No attenuation was observed in the photopic or scotopic a- and b-waves. A secondary wavefront on the descending slope of the scotopic b-wave was the only ERG result that was attenuated in detached retinas. IHC demonstrated anatomical changes in both ON and OFF bipolar cells. Bassoon staining was observed in the remodeled dendrites. Amacrine and horizontal cells did not alter, but Muller cells were clearly reactive with marked extension. Conclusion. Retinal detachment and reattachment were associated with functional and anatomical changes. Exploring the significance of the secondary scotopic wavefront and its association with the remodeling of 2nd- and 3rd-order neurons will shade more light on functional changes and recovery of the retina.

PIE Nacelle Flow Analysis and TCA Inlet Flow Quality Assessment

Science.gov (United States)

Shieh, C. F.; Arslan, Alan; Sundaran, P.; Kim, Suk; Won, Mark J.

1999-01-01

This presentation includes three topics: (1) Analysis of isolated boattail drag; (2) Computation of Technology Concept Airplane (TCA)-installed nacelle effects on aerodynamic performance; and (3) Assessment of TCA inlet flow quality.

Detached concern of forensic mental health nurses in therapeutic relationships with patients the application of the early recognition method related to detached concern.

Science.gov (United States)

Fluttert, Frans; van Meijel, Berno; Nijman, Henk; Bjørkly, Stål; Grypdonck, Mieke

2010-08-01

Improvement of the interaction between forensic mental health nurses and patients may lead to a reduction of inpatient violence. The concept under study is detached concern, which refers to nurses' skills to neutralize the emotional appeal of patients by a balanced attitude between objectivity and emotional involvement. The Patient Contact Questionnaire (PCQ) aims at measuring the degree of concern of nurses for their patients. The PCQ was applied in a pretest-posttest design, evaluating the effects of the Early Recognition Method (ERM). This method aims at the prevention of inpatient violence in forensic psychiatry. Subjects were 116 forensic mental heath nurses working on 16 wards of a large Dutch forensic hospital. First, the baseline scores were compared to scores reported in an earlier study conducted in general psychiatry. Second, pretest-posttest comparisons were carried out for all nurses, and for subgroups of nurses with regard to gender, educational level, years of working experience, and patient population. Third, pretest-posttest comparisons were made on the PCQ item level. The baseline scores of male nurses indicated significantly higher levels of concern than those of female nurses. In addition, more experienced nurses scored significantly higher with regard to concern than less experienced nurses. When comparing the scores before and after applying ERM, no significant differences were found. However, the sores of female nurses showed a tendency toward more concern after implementation of ERM. Detached concern may be a meaningful concept in forensic mental health nursing in measuring nurses' concern for their patients. Levels of detached concern did not change significantly after application of ERM. However, the application of the PCQ could contribute to a better understanding of the interaction between nurses and their patients. 2010 Elsevier Inc. All rights reserved.

Evaluation of the macular architecture of patients operated on from macula-off rhegmatogenous retinal detachment using optical coherence tomography

International Nuclear Information System (INIS)

Ramos Lopez, Meisy; Obret Mendive, Isabel; Hernandez Silva, Juan Raul

2010-01-01

With the support of optical coherence tomography, to evaluate the macular condition of the patients operated on from rhegmatogenous retinal detachment, with detached macula, who underwent buckling surgery and pars plana vitrectomy

Imaging findings of spontaneous detachment of the deltoid muscle as a complication of massive rotator cuff tear

International Nuclear Information System (INIS)

Bianchi, Stefano; Martinoli, Carlo; Abdelwahab, Ibrahim Fikry

2006-01-01

A tear at the origin of the deltoid muscle is uncommon and usually occurs as a complication of shoulder surgery. We report a case of spontaneous deltoid detachment as a complication of massive rotator cuff tear in a 70-year-old woman evaluated by standard radiographs, ultrasound, arthrography and MR-arthrography. We present the multimodality imaging findings with review of the literature. We found that ultrasound is an accurate modality in detecting and assessing spontaneous detachment of the deltoid muscle. As ultrasound is a noninvasive, low-cost, and universally available imaging modality we suggest using ultrasound as the first modality for evaluation of spontaneous detachment of the deltoid muscle. (orig.)

Determination of the capabilities of a detachment for neutralizing chemical attack effects in the brigade defense zone

Directory of Open Access Journals (Sweden)

Dejan R. Inđić

2012-04-01

Full Text Available This paper presents one possible way of deploying detachments for neutralizing the effects of chemical attacks in a brigade defense zone. The detachment composition is provisional and depends on the assessment of whether the enemy in the incoming combat will use weapons of mass destruction. A detachment consists of several organizational units: medical care forces, chemical reconnaissance forces, forces for the establishment of combat efficiency and chemical decontamination forces. The capabilities of the mentioned forces depend on their size, equipment, training level, extent of effects and combat conditions. The paper indicates a potential to overcome the gap in the provisions after disbanding the Army Corps.

Long-term Morphological Modeling at Coastal Inlets

Science.gov (United States)

2015-05-15

that of Humboldt Bay, CA. The model reproduces reasonably well several geomorphic and hydrodynamic features of the inlet at Humboldt Bay. The...geometries, and model setup (e.g., sediment transport formulas) to investigate the controlling geomorphic parameters and the applicability of the CMS...2015 9 The model reproduces the general geomorphic features of Humboldt Bay. The ebb shoal volume is in the lower range of the estimated amount

Analysis of detached recombining plasmas by collisonal-radiative model with energetic electron component

International Nuclear Information System (INIS)

Ohno, N.; Motoyama, M.; Takamura, S.

2001-01-01

Investigation of plasma detachment is still one of the most important subjects in the edge plasma of magnetically confined fusion devices. It was found that volumetric plasma recombination plays an essential role on reduction of particle flux in detached plasmas. The volumetric plasma recombination process has been confirmed in several diverted tokamaks and linear simulators by observing line emission from highly excited states due to three-body recombination process and continuum emission due to radiative recombination process. Electron temperature and density in the detached plasma were also evaluated from analysis of the light emission. To determine the electron temperature, the line emission spectrum is analyzed to calculate the population densities of excited levels. The population distribution among the highly excited states follows the Saha-Boltzmann distribution very closely. This implies that those states are in local thermal equilibrium (LTE) condition with free electrons in plasma so that the electron temperature can be obtained by using method of Boltzmann plot. Another method to determine the electron temperature is to compare the observed continuum spectrum with the theoretically calculated one. In our experiments using the linear diverter simulator, however, there is a clear difference for two evaluated values. One of the possible reasons is thought to be that there is a small amount of energetic electrons existing in detached recombining region. In order to evaluate the electron temperature more preciously, we need to investigate the influence of the energetic electrons on the evaluation of bulk electron temperature in a detached plasma. Collisonal-radiative (GR) model has been utilized for analyzing the light emission intensities from plasma. However, Maxwellian electron distribution function is usually assumed in the CR model. In this paper, we report a quantitative analysis of the line emission spectrum in the detached recombining plasmas by

Inicial nasal mucosa detachment using piezoelectric device in the Le Fort I osteotomy: A technical note

OpenAIRE

Shinohara, Elio Hitoshi; Kaba, Shajadi Carlos Pardo; Ruiz, Marcelo Martinson; Horikawa, Fernando Kendi

2013-01-01

In maxillary Le Fort I type osteotomy the detachment of the nasal mucosa should be done carefully. Piezoelectric surgery contributed much to increase the safety of osteotomies, despite the initial advantage of minimizing the risk of injury in nervous tissue, mainly in bilateral sagittal split osteotomy; we use the piezoelectric device for the initial detachment of the nasal mucosa in the maxillary osteotomy.

Aerosol Inlet Characterization Experiment Report

Energy Technology Data Exchange (ETDEWEB)

Bullard, Robert L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Kuang, Chongai [Brookhaven National Lab. (BNL), Upton, NY (United States); Uin, Janek [Brookhaven National Lab. (BNL), Upton, NY (United States); Smith, Scott [Brookhaven National Lab. (BNL), Upton, NY (United States); Springston, Stephen R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2017-05-01

The U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility Aerosol Observation System inlet stack was characterized for particle penetration efficiency from 10 nm to 20 μm in diameter using duplicate scanning mobility particle sizers (10 nm-450 nm), ultra-high-sensitivity aerosol spectrometers (60 nm-μm), and aerodynamic particle sizers (0.5 μm-20 μm). Results show good model-measurement agreement and unit transmission efficiency of aerosols from 10 nm to 4 μm in diameter. Large uncertainties in the measured transmission efficiency exist above 4 μm due to low ambient aerosol signal in that size range.

Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser.

Science.gov (United States)

Chandra, Parijat; Tewari, Ruchir; Salunkhe, Nitesh; Kumawat, Devesh; Kumar, Vinod

2017-06-29

Rhegmatogenous retinal detachment after successfully regressed retinopathy of prematurity is a rare occurrence. Late onset rhegmatogenous retinal detachment has been reported infrequently. The authors report a case of aggressive posterior retinopathy of prematurity that underwent uneventful regression after laser photocoagulation and later developed an inoperable closed funnel retinal detachment due to a giant retinal tear. This case represents the earliest development of such complications in regressed aggressive posterior retinopathy of prematurity treated by laser. Development of a giant retinal tear has also not been previously reported after laser treatment. This case highlights that successful regression of severe retinopathy of prematurity does not safeguard against future complications and requires frequent long-term follow-up. [J Pediatr Ophthalmol Strabismus. 2017;54:e34-e36.]. Copyright 2017, SLACK Incorporated.

Optimal sensor placement for control of a supersonic mixed-compression inlet with variable geometry

Science.gov (United States)

Moore, Kenneth Thomas

A method of using fluid dynamics models for the generation of models that are useable for control design and analysis is investigated. The problem considered is the control of the normal shock location in the VDC inlet, which is a mixed-compression, supersonic, variable-geometry inlet of a jet engine. A quasi-one-dimensional set of fluid equations incorporating bleed and moving walls is developed. An object-oriented environment is developed for simulation of flow systems under closed-loop control. A public interface between the controller and fluid classes is defined. A linear model representing the dynamics of the VDC inlet is developed from the finite difference equations, and its eigenstructure is analyzed. The order of this model is reduced using the square root balanced model reduction method to produce a reduced-order linear model that is suitable for control design and analysis tasks. A modification to this method that improves the accuracy of the reduced-order linear model for the purpose of sensor placement is presented and analyzed. The reduced-order linear model is used to develop a sensor placement method that quantifies as a function of the sensor location the ability of a sensor to provide information on the variable of interest for control. This method is used to develop a sensor placement metric for the VDC inlet. The reduced-order linear model is also used to design a closed loop control system to control the shock position in the VDC inlet. The object-oriented simulation code is used to simulate the nonlinear fluid equations under closed-loop control.

Prophylactic treatment to the fellow eye of patients with phakic lattice retinal detachment: analysis of failures and risks of treatment.

Science.gov (United States)

Folk, J C; Bennett, S R; Klugman, M R; Arrindell, E L; Boldt, H C

1990-01-01

The authors performed a retrospective analysis on 296 phakic patients who had bilateral lattice degeneration and a retinal detachment in one eye. The analysis was done to determine the complications of full prophylactic treatment to lattice and breaks in the fellow eye and to explain the reasons that this treatment sometimes did not prevent new retinal breaks or detachments. The patients were followed for a mean +/- SD of 7.415 +/- 5.422 years after their first detachment. Twenty-four new tears occurred in the fellow eyes during this time, seven (29.2%) of which were away from areas of visible lattice. Prophylactic treatment did not appear to cause new tears or increase the risk of detachment if a new tear occurred. It also did not compromise the surgical repair in those patients who had eyes in which new breaks or detachments developed. The risk of visual loss was similar in those patients receiving prophylactic treatment compared with those not receiving treatment.

Visualization of intermittent blobby plasma transport in attached and detached plasmas of the NAGDIS-II

International Nuclear Information System (INIS)

Ohno, Noriyasu; Furuta, Katsuhiro; Takamura, Shuichi

2004-01-01

We investigated the intermittent convective plasma transport in a attached and/or detached plasma condition of the linear divertor plasma simulator, NAGDIS-II. Images taken by a fast-imaging camera clearly show that in attached plasmas, blobs are peeled off the bulk plasma, and propagate outward with an azimuthal motion. In detached plasmas, plasma turbulence observed near the plasma recombining region drives strong intermittent radial plasma transport, which could broaden the radial density profile. (author)

Cook Inlet and Kenai Peninsula, Alaska ESI: INDEX (Index Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains vector polygons representing the boundaries used in the creation of the Environmental Sensitivity Index (ESI) for Cook Inlet and Kenai...

Flow hydrodynamics near inlet key of Piano Key Weir (PKW)

Indian Academy of Sciences (India)

Department of Water Resources Development and Management, Indian Institute ... on the hydrodynamic performance near inlet key of Piano Key Weir (PKW). ... nature of flows is clearly understood with the help of advanced instrumentation.

Cook Inlet and Kenai Peninsula, Alaska ESI: BIRDS (Bird Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains biological resource data for alcids, shorebirds, waterfowl, diving birds, pelagic birds, gulls and terns in Cook Inlet and Kenai Peninsula,...

Cook Inlet and Kenai Peninsula, Alaska ESI: NESTS (Nest Points)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains biological resource data for alcids, shorebirds, waterfowl, diving birds, pelagic birds, gulls and terns in Cook Inlet and Kenai Peninsula,...

AFSC/NMML: Cook Inlet Beluga Opportunistic Sightings, 1975 to 2015

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — As a part of National Marine Fisheries Service (NMFS) management of the endangered Cook Inlet beluga whale population, a database of opportunistic beluga whale...