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Sample records for humanities leiden university

  1. Psychology students from Leiden University

    DEFF Research Database (Denmark)

    Singla, Rashmi

    2017-01-01

    We are glad to share with our department that a group of 41 Psychology students from Leiden university, Holland were on a three hours visit to RUC Psychology department on Friday , 10.3.2017. The department is a valuable partner for students’ exchange , almost every semester there are RUC students...... travelling to Leiden. The trip was planned by Study Association Labyrint Leiden, and consisted of students at all levels from the bachelor as well as masters programs. A group of RUC psychology students Wiebke Sandermann; Emma Stinne Engstrøm; Mikkel Brilner Lund were in the organising group along...... with the study director Hans Sønderstrup Hansen and Rashmi Singla. It was an enriching experience for the RUC organizing group. International coordinator for Psychology Dieuwerke de Groot in Leiden reciprocated by writing: “A very enthusiastic mail from our students telling me they had such a wonderful time...

  2. Indigenous Peoples : Local Impacts of International Rights. Valedictory Lecture Leiden University

    NARCIS (Netherlands)

    Persoon, G.A.

    2017-01-01

    Valedictory lecture given by Prof.dr. Gerard A. Persoon Professor of Environment and Development and in particular Indigenous Peoples in Southeast Asia at Leiden University on Monday, October 23 2017Museum Volkenkunde / Ethnographic Museum

  3. Indigenous Peoples: Local Impacts of International Rights. Valedictory Lecture Leiden University

    OpenAIRE

    Persoon, G.A.

    2017-01-01

    Valedictory lecture given by Prof.dr. Gerard A. Persoon Professor of Environment and Development and in particular Indigenous Peoples in Southeast Asia at Leiden University on Monday, October 23 2017Museum Volkenkunde / Ethnographic Museum

  4. Key Inflammatory Processes in Human NASH Are Reflected in Ldlr-/-.Leiden Mice: A Translational Gene Profiling Study.

    Science.gov (United States)

    Morrison, Martine C; Kleemann, Robert; van Koppen, Arianne; Hanemaaijer, Roeland; Verschuren, Lars

    2018-01-01

    Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic mechanisms requires the use of pre-clinical models, for instance for time-resolved studies. Such models must reflect molecular disease processes of importance in patients. Herein we characterized inflammation in NASH patients on the molecular level by transcriptomics and investigated whether key human disease pathways can be recapitulated experimentally in Ldlr -/- .Leiden mice, an established pre-clinical model of NASH. Methods: Human molecular inflammatory processes were defined using a publicly available NASH gene expression profiling dataset (GSE48452) allowing the comparison of biopsy-confirmed NASH patients with normal controls. Gene profiling data from high-fat diet (HFD)-fed Ldlr -/- .Leiden mice (GSE109345) were used for assessment of the translational value of these mice. Results: In human NASH livers, we observed regulation of 65 canonical pathways of which the majority was involved in inflammation (32%), lipid metabolism (16%), and extracellular matrix/remodeling (12%). A similar distribution of pathways across these categories, inflammation (36%), lipid metabolism (24%) and extracellular matrix/remodeling (8%) was observed in HFD-fed Ldlr -/- .Leiden mice. Detailed evaluation of these pathways revealed that a substantial proportion (11 out of 13) of human NASH inflammatory pathways was recapitulated in Ldlr -/- .Leiden mice. Furthermore, the activation state of identified master regulators of inflammation (i.e., specific transcription factors, cytokines, and growth factors) in human NASH was largely reflected in Ldlr -/- .Leiden mice, further substantiating its translational value. Conclusion: Human NASH is characterized by upregulation of specific

  5. History and highlights of the teratological collection in the Museum Anatomicum of Leiden University, The Netherlands

    NARCIS (Netherlands)

    Boer, Lucas L.; Boek, Peter L. J.; van Dam, Andries J.; Oostra, Roelof-Jan

    2018-01-01

    The anatomical collection of the Anatomical Museum of Leiden University Medical Center (historically referred to as Museum Anatomicum Academiae Lugduno-Batavae) houses and maintains more than 13,000 unique anatomical, pathological and zoological specimens, and include the oldest teratological

  6. Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

    Science.gov (United States)

    Morrison, Martine C.; Kleemann, Robert; van Koppen, Arianne; Hanemaaijer, Roeland; Verschuren, Lars

    2018-01-01

    Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic mechanisms requires the use of pre-clinical models, for instance for time-resolved studies. Such models must reflect molecular disease processes of importance in patients. Herein we characterized inflammation in NASH patients on the molecular level by transcriptomics and investigated whether key human disease pathways can be recapitulated experimentally in Ldlr−/−.Leiden mice, an established pre-clinical model of NASH. Methods: Human molecular inflammatory processes were defined using a publicly available NASH gene expression profiling dataset (GSE48452) allowing the comparison of biopsy-confirmed NASH patients with normal controls. Gene profiling data from high-fat diet (HFD)-fed Ldlr−/−.Leiden mice (GSE109345) were used for assessment of the translational value of these mice. Results: In human NASH livers, we observed regulation of 65 canonical pathways of which the majority was involved in inflammation (32%), lipid metabolism (16%), and extracellular matrix/remodeling (12%). A similar distribution of pathways across these categories, inflammation (36%), lipid metabolism (24%) and extracellular matrix/remodeling (8%) was observed in HFD-fed Ldlr−/−.Leiden mice. Detailed evaluation of these pathways revealed that a substantial proportion (11 out of 13) of human NASH inflammatory pathways was recapitulated in Ldlr−/−.Leiden mice. Furthermore, the activation state of identified master regulators of inflammation (i.e., specific transcription factors, cytokines, and growth factors) in human NASH was largely reflected in Ldlr−/−.Leiden mice, further substantiating its translational value. Conclusion: Human NASH is characterized by upregulation of specific

  7. Jewish Medical Students and Graduates at the Universities of Padua and Leiden: 1617–1740

    Directory of Open Access Journals (Sweden)

    Kenneth Collins

    2013-01-01

    Full Text Available The first Jewish medical graduates at the University of Padua qualified in the fifteenth century. Indeed, Padua was the only medical school in Europe for most of the medieval period where Jewish students could study freely. Though Jewish students came to Padua from many parts of Europe the main geographical sources of its Jewish students were the Venetian lands. However, the virtual Padua monopoly on Jewish medical education came to an end during the seventeenth century as the reputation of the Dutch medical school in Leiden grew. For aspiring medieval Jewish physicians Padua was, for around three hundred years, the first, simplest, and usually the only choice.

  8. Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice

    NARCIS (Netherlands)

    Winther, M.P.J. de; Gijbels, M.J.J.; Dijk, K.W. van; Gorp, P.J.J. van; Suzuki, H.; Kodama, T.; Frants, R.R.; Havekes, L.M.; Hofker, M.H.

    1999-01-01

    Apolipoprotein (apo) E3Leiden is a dysfunctional apo E variant associated with familial dysbetalipoproteinemia in humans. Transgenic mice carrying the APOE3Leiden gene develop hyperlipidemia and are highly susceptible to diet-induced atherosclerosis. An early step in atherosclerosis is foam cell

  9. Frequency of factor V Leiden mutation

    International Nuclear Information System (INIS)

    Nasiruddin; Ali, W.; Rehman, Z.; Anwar, M.; Ayyub, M.; Ali, W.; Ahmed, S.

    2005-01-01

    Objective: To determine the frequency of factor V Leiden mutation. Design: Observational study. Patients and Methods: Two hundred subjects each of apparently healthy and unrelated Punjabi and Pathan origins were included in the study. Peripheral blood samples were collected in EDTA and DNA extracted by phenol- chloroform extraction method. DNA analysis was done by PCR for restriction fragment length polymorphism. The product was digested overnight with Mn/1 and electrophoresed on acrylamide gel to detect 67 and 153 base pair fragments of factor V Leiden against 37, 67 and 116 base pair fragments of normal factor V. Results: In the 400 subjects studied, only 5 cases of heterozygotes for factor V Leiden were detected. The overall carrier rate was 1.3% (95% CI 0.2-2.2%). The carrier rate in Punjabis and Pathans was 1 % and 1.5% respectively. Conclusion: This study confirms that the prevalence of factor V Leiden is low in Asians and Africans as compared to the European population. (author)

  10. Leiden Mutation and the Course of Severe Acute Pancreatitis

    Directory of Open Access Journals (Sweden)

    A. V. Ershov

    2013-01-01

    Full Text Available Objective: to evaluate the impact of Leiden mutation on the course of severe acute pancreatitis. Subjects and methods. One hundred and twelve people were examined. Group 1 comprised 50 patients diagnosed with severe acute pancreatitis without coagulation factor V (Leiden mutation. Group 2 included 42 patients with severe acute pancreatitis who were found to have Leiden mutation. Acute pancreatitis was first diagnosed in both groups. Group 3 consisted of 20 apparently healthy individuals (a control group. The severity of the underlying disease was determined in accordance with the clinical and laboratory parameters recommended by the I. I. Dzhanelidze Saint Petersburg Research Institute of Emergence Care. Results. This investigation revealed an association of Leiden mutation with trends in the development of acute pancreatitis. Group 2 exhibited a more severe disease: large focal pancreatic necrosis was twice more common and infectious complications developed more frequently; more aggressive and radical treatments were more often used. The patients with Leiden mutation had higher mortality rates (33% in the Leiden mutation group and 24% in the non-mutation group. Conclusion. The findings should be kept in mind in elaborating new diagnostic methods and principles in the treatment of the underlying disease and in the prevention of its complications in patients with severe acute pancreatitis. Key words: acute pancreatitis, Leiden mutation.

  11. Factor V Leiden mutation in pregnancy.

    Science.gov (United States)

    Cohen, Susan Murphy

    2004-01-01

    Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and 1% of the Black populations. Nurses should be knowledgeable about screening for and diagnosis of factor V Leiden mutation, risk reduction counseling, recommended care of the affected patient, and implications of anticoagulant therapy during the perinatal period.

  12. 21 CFR 864.7280 - Factor V Leiden DNA mutation detection systems.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Factor V Leiden DNA mutation detection systems....7280 Factor V Leiden DNA mutation detection systems. (a) Identification. Factor V Leiden deoxyribonucleic acid (DNA) mutation detection systems are devices that consist of different reagents and...

  13. Mistaken Identity and Mirror Images: Albert and Carl Einstein, Leiden and Berlin, Relativity and Revolution

    NARCIS (Netherlands)

    van Dongen, J.A.E.F.

    2012-01-01

    Albert Einstein accepted a “special” visiting professorship at the University of Leiden in the Netherlands in February 1920. Although his appointment should have been a mere formality, it took until October of that year before Einstein could occupy his special chair. Why the delay? The explanation

  14. Polychaeten aus den Zoologischen Museen von Leiden und Amsterdam I

    NARCIS (Netherlands)

    Augener, H.

    1933-01-01

    In der vorliegenden Arbeit ist die Untersuchung eines sehr umfangreichen Polychaeten-Materials niedergelegt, das mir von Herrn Prof. Dr. E. D. van Oort in Leiden und Herrn Prof. Dr. L. F. de Beaufort in Amsterdam zur Bearbeitung übergeben wurde. Von diesem Material ist der dem Museum in Leiden

  15. Clashes of discourses: Humanists and Calvinists in seventeenth-century academic Leiden

    NARCIS (Netherlands)

    Kromhout, D.

    2016-01-01

    Using Michel Foucault's concept of discursive change and Stephen Greenblatt's ideas about social poetics and self-fashioning, 'Clashes of Discourses: Calvinists and Humanists in Seventeenth-Century Academic Leiden' explains developments in the literary works of leading Leiden humanists against the

  16. Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice

    NARCIS (Netherlands)

    Westerterp, M.; Hoogt, C.C. van der; Haan, W. de; Offerman, E.H.; Dallinga-Thie, G.M.; Jukema, J.W.; Havekes, L.M.; Rensen, P.C.N.

    2006-01-01

    OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a humanized lipoprotein profile. METHODS AND RESULTS -

  17. Weldenkende burgers en Oranjeliefhebbers. Patriotten en Prinsgezinden in Leiden, 1775-1795

    NARCIS (Netherlands)

    de Jong, E.H.

    2014-01-01

    This book deals with the conflicts between Patriots and Orangists in Leiden, which will be assessed with the help of the theory of collective action by the American sociologist Charles Tilly. The urban economy in Leiden was dominated by a textile industry that concentrated on exports and was very

  18. Report on the International Workshop “The Golden Horde in a Global Perspective: Imperial Strategies”, Leiden University, May 7–8, 2015 »

    Directory of Open Access Journals (Sweden)

    Roman Hautala

    2015-09-01

    Full Text Available This article contains a report on the international conference organized by the University of Leiden in May 2015. According to its organizers, this conference has become the first Western European symposium dedicated to the study of the long history of the Golden Horde. The conference became a fruitful meeting place of the leading Russian and Tatar historians and archaeologists with their Western colleagues from the Netherlands, United Kingdom, United States of America, Hungary, Poland, and Finland. International participants of the Leiden conference discussed the most topical issues of historiography associated with eventful history of the Golden Horde. In particular, the conference participants paid special attention to the study of the administration of the ulus of Jochi that naturally combined governmental models of the Mongol Empire of the Chingizids with local administrative elements. A separate section of the conference was devoted to the analysis of the religious policy of the Golden Horde khans, where special attention was paid to the historiographical debate on the Islamization of the ulus of Jochi. The conference participants also paid considerable attention to the consideration of the material culture of the Golden Horde known both from written sources and, above all, from the materials of archaeological findings. Also, a number of reports of the confe­rence was devoted to foreign and domestic policies of the Golden Horde rulers, at the same time reflecting the central geopolitical role of the ulus of Jochi on the Eurasian continent and the high level of civilization of the Golden Horde. The main achievement of the Leiden conference was a statement on the need of deeper study of the Golden Horde history in order to overcome a number of stereotypes regarding misconceptions of the ulus of Jochi represented as backward and parasitic State formation. The conference participants agreed in general opinion about the necessity of similar

  19. Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome

    DEFF Research Database (Denmark)

    Benfield, Thomas L; Dahl, Mortens; Nordestgaard, Borge G

    2005-01-01

    The effect of the coagulation factor V Leiden mutation on infectious disease susceptibility and outcome is controversial.......The effect of the coagulation factor V Leiden mutation on infectious disease susceptibility and outcome is controversial....

  20. The Association of Factor V Leiden Mutation with Recurrent Pregnancy Loss

    International Nuclear Information System (INIS)

    Kashif, M.; Saeed, A.

    2015-01-01

    Objective: To determine the association of factor V Leiden mutation with recurrent pregnancy loss. Methods: The case-control study was conducted at the Department of Haematology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from January to June 2012, and comprised women of 18 to 45 years of age who had a history of recurrent pregnancy loss, and controls with no history of pregnancy loss. All the subjects belonged to Punjabi ethnic group. Three ml blood was taken from cases and controls and deoxyribonucleic acid was extracted. In order to identify Factor V Leiden mutation, polymerase chain reaction method was utilised combined with the amplification refractory mutation system. Data was analysed using SPSS 17. Results: Of the 112 subjects, 56(50 percent) were in each of the two groups. The presence of factor V Leiden mutation among the cases was 3(5.4 percent) while it was absent among the controls. The mutation was significantly associated with recurrent pregnancy loss (p=0.017).Recurrent pregnancy loss was higher in cases than controls (p=0.001). Conclusion: Factor V Leiden mutation was significantly associated with recurrent pregnancy loss. It should be considered one of the causes of recurrent pregnancy loss. (author)

  1. Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study

    NARCIS (Netherlands)

    Schouten, Marcel; van 't Veer, Cornelis; Roelofs, Joris Jth; Levi, Marcel; van der Poll, Tom

    2010-01-01

    Introduction: Streptococcus (S.) pneumoniae is the most common cause of community-acquired pneumonia. The factor V Leiden (FVL) mutation results in resistance of activated FV to inactivation by activated protein C and thereby in a prothrombotic phenotype. Human heterozygous FVL carriers have been

  2. Sensitive Dual Color in vivo Bioluminescence Imaging Using a New Red Codon Optimized Firefly Luciferase and a Green Click Beetle Luciferase

    Science.gov (United States)

    2011-04-01

    Bologna, Italy, 2 Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands, 3 Department of...and approved by the Bioethics Committee of Leiden University, The Netherlands (Animal protocol 08158). Allanimals received humane care in compliance

  3. Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice : An immunohistochemical study

    NARCIS (Netherlands)

    Gijbels, M.J.J.; Cammen, M. van der; Laan, L.J.W. van der; Emeis, J.J.; Havekes, L.M.; Hofker, M.H.; Kraal, G.

    1999-01-01

    Apolipoprotein E3-Leiden (APOE3-Leiden) transgenic mice develop hyperlipidemia and are highly susceptible to diet-induced atherosclerosis. We have studied the progression and regression of atherosclerosis using immunohistochemistry. Female transgenic mice were fed a moderate fat diet to study

  4. Mechanisms of the factor V Leiden paradox

    NARCIS (Netherlands)

    van Stralen, K. J.; Doggen, C. J. M.; Bezemer, I. D.; Pomp, E. R.; Lisman, T.; Rosendaal, F. R.

    2008-01-01

    Objective-Carriers of the factor V Leiden mutation (FVL-carriers) have a substantially increased risk of deep venous thrombosis (DVT), whereas the risk of pulmonary embolism (PE) is only mildly increased compared with noncarriers. So far few studies have investigated possible mechanisms for this

  5. The Trouble with Opium. Taste, Reason and Experience in Late Galenic Pharmacology with Special Regard to the University of Leiden (1575-1625).

    Science.gov (United States)

    Klerk, Saskia

    2014-01-01

    In the seventeenth century, the discrepancy between the taste of some drugs and their effects on the body was used to criticize Galenic medicine. In this paper, I argue that such contradictions were brought to light by the sixteenth-century study of drug properties within the Galenic tradition itself. Investigating how the taste of a drug corresponded to the effects it had on the body became a core problem for maintaining a medical practice that was both rational and effective. I discuss four physicians, connected to the University of Leiden, who attempted to understand drug properties, including taste, within a Galenic framework. The sixteenth-century discussions about the relationship between the senses, reason and experience, will help us understand the seventeenth-century criticism of Galenic medicine and the importance of discussions about materia medica for ideas regarding the properties of matter proposed in this period.

  6. Effects of dietary fish oil on serum lipids and VLDL kinetics in hyperlipidemic apolipoprotein E*3-Leiden transgenic mice

    NARCIS (Netherlands)

    Vlijmen, B.J.M. van; Mensink, R.P.; Hof, H.B. van 't; Offermans, R.F.G.; Hofker, M.H.; Havekes, L.M.

    1998-01-01

    Studying the effects of dietary fish oil on VLDL metabolism in humans is subject to both large intra- and interindividual variability. In the present study we therefore used hyperlipidentic apolipoprotein (APO) E*3-Leiden mice, which have impaired chylomicron and very low density lipoprotein (VDL)

  7. Evaluation the frequency of factor V Leiden mutation in pregnant women with preeclampsia syndrome in an Iranian population

    Directory of Open Access Journals (Sweden)

    Azadeh Azinfar

    2012-01-01

    Full Text Available Background: Role of genetic factors in etiology of preeclampsia is not confirmed yet.Objective: Gene defect frequency varies in different geographic areas as well as ethnic groups. In this study, the role of factor V Leiden mutation in the pathogenesis of preeclampsia syndrome among the pregnant population of northern shore of Persian Gulf in Iran, were considered.Materials and Methods: Between Jan. 2008 and Dec. 2009, in a nested case control study, pregnant women with preeclampsia (N=198 as cases and healthy (N=201 as controls were enrolled in the study. DNA were extracted from 10 CC peripheral blood and analyzed for presence of factor V Leiden mutation in these subjects. The maternal and neonatal outcomes of pregnancy according to the distribution of factor V Leiden were also compared among cases.Results: In total, 17(8.6% of cases and 2(1% of controls showed the factor V Leiden mutation. The incidence of factor V Leiden was typically higher in preeclamptic women than control group (OR: 9.34 %95 CI: 2.12-41.01. There was no difference in incidence rate of preterm delivery< 37 weeks (OR: 1.23 %95 CI: 0.38-4.02, very early preterm delivery<32 weeks (OR: 1.00 %95 CI: 0.12-8.46, intra uterine fetal growth restriction (IUGR (OR: 1.32 %95 CI: 0.15-11.30 ,and the rate of cesarean section (OR: 0.88 %95 CI: 0.29-2.62 among cases based on the prevalence of factor V Leiden mutation.Conclusion: The pregnant women with factor V Leiden mutation are prone for preeclampsia syndrome during pregnancy, but this risk factor was not correlated to pregnancy complications in the studied women

  8. Anécdotas castellanas en escritura hebraica. Apuntes paremiológicos conservados en las anotaciones hebreas de Alfonso de Zamora (Ms. Leiden Or. 645

    Directory of Open Access Journals (Sweden)

    Alonso Fontela, Carlos

    2011-12-01

    Full Text Available Problems of translation and interpretation are addressed in this presentation of Alfonso de Zamora’s Hebrew and Hebrew “Aljamiado” Spanish notes (ca. 1530 from Leiden University Library Ms. Or. 645 (ol. Warner 65 containing anecdotes, sayings and short tales. Additional notes dealing with a manuscript copy of the Targum to the Prophets comissioned by the University of Salamanca are also discussed.

    Este artículo estudia algunas notas manuscritas de Alfonso de Zamora en hebreo y en aljamía hebraico-castellana datadas hacia 1530, y procedentes del ms. Or. 645 (ol. Warner 65 de la Biblioteca de la Universidad de Leiden. Dichas notas contienen anécdotas, refranes y «cuentecillos», tales como las anécdotas «de fray Palomo», «de un portugués», y «de lo que dijo el gallego». Otras anotaciones de Zamora tratan de un trabajo de copia del Targum a los Profetas por encargo de la Universidad de Salamanca.

  9. Note sur les Buprestides du Museum de Leiden

    NARCIS (Netherlands)

    Thery, A.

    1935-01-01

    M. le Dr. H. C. Blöte, entomologiste du Rijksmuseum van Natuurlijke Historie à Leiden (Hollande) m'a confié l'étude de matériaux indéterminés appartenant aux collections de cet établissement, parmi ceux-ci j'ai trouvé quelques espèces nouvelles dont je donne ci-dessous la description. Les types de

  10. Factor V Leiden is associated with increased sperm count

    NARCIS (Netherlands)

    van Mens, T. E.; Joensen, U. N.; Bochdanovits, Z.; Takizawa, A.; Peter, J.; Jørgensen, N.; Szecsi, P. B.; Meijers, J. C. M.; Weiler, H.; Rajpert-de Meyts, E.; Repping, S.; Middeldorp, S.

    2017-01-01

    STUDY QUESTION: Is the thrombophilia mutation factor V Leiden (FVL) associated with an increased total sperm count? SUMMARY ANSWER: Carriers of FVL have a higher total sperm count than non-FVL-carriers, which could not be explained by genetic linkage or by observations in a FVL-mouse model. WHAT IS

  11. Apolipoprotein E*3-Leiden transgenic mice mode for hypolipidaemic drugs

    NARCIS (Netherlands)

    Vlijmen, B.J.M. van; Pearce, N.J.; Bergö, M.; Staels, B.; Yates, J.W.; Gribble, A.D.; Bond, B.C.; Hofker, M.H.; Havekes, L.M.; Groot, P.H.E.

    1998-01-01

    Apolipoprotein (APO) E*3-Leiden mice with impaired chylomicron and VLDL (very low density lipoprotein) remnant metabolism display hyperlipidaemia and atherosclerosis. In the present study, these mice were used for testing the hypolipidaemic effect of two marketed agents, lovastatin (CAS 75330-75-5)

  12. Growth in The Hague versus decline in Leiden. A comparison of spatial development in two Dutch cities between 1700 and 1870

    Directory of Open Access Journals (Sweden)

    Jelmer van der Zweep

    2017-04-01

    1830–1870 The Hague underwent considerable densification inside the canal ring as well as extensions north and south of the city. The number of new tenements built on inner yards in The Hague can give a distorted impression, as can the number of demolished buildings in Leiden, because the 1870 maps were much more detailed. In Leiden the advent of new factories prompted new construction on the former city walls. The Hague, too, became a major industrial player, while continuing to profit from its function as the centre of government. In 1870, The Hague had almost twoand-a-half times as many inhabitants as Leiden (92,000 versus 39,000, but within the canal girdle Leiden was still more densely built up. Between 1700 and 1870, The Hague developed into one of the Netherlands’ biggest cities, which it still is. Leiden plummeted from second place to the middle bracket, where it continues to sit today.

  13. Verzeichnis der Echiuridae, Sipunculidae und Priapulidae des Naturhistorichen Reichsmuseums in Leiden

    NARCIS (Netherlands)

    Stiasny, G.

    1930-01-01

    Die vorliegende Mitteilung ist das Ergebnis der Bearbeitung zumeist älteren Materiales an Echiuriden, Sipunculiden und Priapuliden des Naturhistorischen Reichs-Museums in Leiden. Obwohl die Sammlung nach Anzahl der Exemplare nicht umfangreich ist, zeigt sie einen überraschenden Reichtum an Formen

  14. Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice

    NARCIS (Netherlands)

    Delsing, D.J.; Jukema, J.W.; van de Wiel, M.A.; Emeis, J.; van der Laarse, A.; Havekes, L.M.; Princen, H.M.G.

    2003-01-01

    This study was designed to investigate the potential antiatherosclerotic effects of the calcium antagonist amlodipine as compared with the HMG-CoA reductase inhibitor atorvastatin and the combination of both in ApoE*3-Leiden transgenic mice. Four groups of 15 ApoE*3-Leiden mice were put on a

  15. A half century of abstracting at the African Studies Centre Leiden

    NARCIS (Netherlands)

    Doorn, van M.C.A.

    2013-01-01

    The article discusses the history of the abstracts and indexing journal originally known as 'Documentatieblad,' which was renamed to 'African Studies Abstracts (ASA)' and later to 'African Studies Abstracts Online' (ASAO), published by the African Studies Centre (ASC) in Leiden, the Netherlands

  16. Meta-analysis of factor V Leiden and ischemic stroke in young adults: the importance of case ascertainment.

    Science.gov (United States)

    Hamedani, Ali G; Cole, John W; Mitchell, Braxton D; Kittner, Steven J

    2010-08-01

    The factor V Leiden mutation is associated with ischemic stroke in children but not in adults. Whether it is associated with ischemic stroke in young adults, however, is uncertain. To address this issue, we performed a meta-analysis of 18 case-control studies of ischemic stroke in adults 50 years of age and younger published before June 2009. Across all studies, factor V Leiden was detected in 154 of 2045 cases (7.5%) and 217 of 5307 controls (4.1%), yielding a fixed-effect odds ratio of 2.00 (95% CI, 1.59-2.51). However, further analyses revealed substantial heterogeneity among these studies (P=0.005 for Q-test of heterogeneity). Hypothesizing that this heterogeneity could be related to differences among studies in case selection criteria, we stratified the meta-analysis into studies for which case samples were enriched or not enriched to include cases having an increased likelihood of prothrombotic genetic involvement ("selected" ischemic stroke studies, n=9) and those that recruited cases from consecutive neurology referrals or hospitalizations ("unselected" ischemic stroke studies, n=8). Among the 9 "selected" ischemic stroke studies, factor V Leiden was more strongly associated with stroke (OR, 2.73; 95% CI, 1.98-3.75), whereas among the 8 "unselected" ischemic stroke studies, the association between factor V Leiden and stroke was substantially weaker (OR, 1.40; 95% CI, 0.998-1.95). This difference was found to be statistically significant (P=0.003 for Woolf test for heterogeneity). We conclude that factor V Leiden is associated with ischemic stroke in young adults, particularly in patient populations in which there is an increased clinical suspicion of prothrombotic state.

  17. Prevalentie van chronische-vermoeidheidsyndroom in 4 huisartspraktijken in de regio Leiden [Prevalence of chronic fatigue syndrome in four general practices in Leyden region

    NARCIS (Netherlands)

    Versluis, R.G.J.A.; Waal, M.W.M. de; Opmeer, C.; Petri, H.; Springer, M.P.

    1997-01-01

    Doel. De prevalentie vaststellen van chronische-vermoeidheidsyndroom (CVS) in de huisartspraktijk. Opzet. Descriptief. Plaats. Huisartspraktijken in Leiden en omstreken. Methode. Het geanonimiseerde geautomatiseerde databestand van het Registratie Netwerk Universitaire Huisartspraktijken Leiden en

  18. Stemcell Information: SKIP000532 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available yology, Leiden University Medical Center, Leiden, and Interuniversity Cardiology Institute of the Netherland...ty Medical Center, Leiden, and Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherl...ands Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, and Interuniversity Cardiology...University Medical Center, Leiden, and Interuniversity Cardiology Institute of th... Embryology, Leiden University Medical Center, Leiden, and Interuniversity Cardiology Institute of the Nethe

  19. Factor V G1691A (Leiden is a major etiological factor in Egyptian Budd-Chiari syndrome patients

    Directory of Open Access Journals (Sweden)

    Tawhida Y. Abdel Ghaffar

    2011-12-01

    Full Text Available Objective: Budd-Chiari syndrome is a multifactorial disease in which several prothrombotic disorders may predispose patients to the development of thrombosis at this uncommon location (hepatic veins. The aim of this study was to determine the prevalence and characteristics of inherited thrombophilia in Egyptian Budd-Chiari syndrome patients.Materials and Methods: The study included 47 Budd-Chiari syndrome patients (20 children and 27 adults. Genotyping of Factor V G1691A (Leiden, prothrombin G20210A (PT, and methylenetetrahydrofolate reductase C677T were performed using real-time PCR and fluorescence melting curve detection analysis.Results: Factor V Leiden was observed in 29 patients (61.7%. It is the only factor that caused Budd-Chiari syndrome in 18 of the patients and in 5 of the patients with inferior vena cava involvement. Myeloproliferative disease was noted in 12 (25.5% patients, antiphospholipid syndrome in 5 (10.6%, and Behcet’s disease in 3 (6.4%. Interestingly, 3 of the children with Budd-Chiari syndrome had lipid storage disease.Conclusion: Factor V Leiden was a major etiological factor in Egyptian Budd-Chiari syndrome patients, which may have been related to the high frequency of this mutation in the study region. Factor V Leiden was also a strong thrombophilic factor and the leading cause of inferior vena cava thrombosis in these patients. Lipid storage disease should be included as a risk factor for Budd-Chiari syndrome.

  20. Gewenst beleid tegen ongewenst gedrag : onveiligheid binnen de organisatie kan leiden tot ziekteverzuim

    NARCIS (Netherlands)

    Dalen, E.J. van; Nuyens, M.

    2005-01-01

    Indimidatie en agressie en geweld op het werk kunnen leiden tot gevoelens van onveiligheid en ziekteverzuim. Bepalingen in de Arbowet hebben onvoldoende effect op beleidsvorming ter voorkoming van ongewenste omgangsvormen. Goede praktijkvoorbeelden van beleid tegen ongewenst gedrag kunnen

  1. Die Scyphomedusen-Sammlung des Naturhistorischen Reichsmuseums in Leiden : II. Stauromedusae, Coronatae, Semaeostomeae

    NARCIS (Netherlands)

    Stiasny, G.

    1919-01-01

    ALLGEMEINER TEIL. Die Bearbeitung der umfangreichen Scyphomedusen-Sammlung im Rijksmuseum van Natuurlijke Historie in Leiden ist nunmehr so weit vorgeschritten, dass sich eine Übersicht über dieselbe gewinnen lässt. In einer früheren Mitteilung wurde über die Cubomedusen berichtet, eine weitere zur

  2. Universal jurisdiction: state of affairs and ways ahead. : A policy paper

    NARCIS (Netherlands)

    L. Zegveld (Liesbeth); J.D. Handmaker (Jeff)

    2012-01-01

    textabstractOn 17 September 2010, the International Institute of Social Studies (ISS), Leiden University and ICCO organised an expert meeting at the ISS on universal jurisdiction (UJ). The meeting was chaired in the morning by Professor John Dugard and in the afternoon by Professor Karin Arts. The

  3. Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.

    Science.gov (United States)

    Westrick, Randal J; Tomberg, Kärt; Siebert, Amy E; Zhu, Guojing; Winn, Mary E; Dobies, Sarah L; Manning, Sara L; Brake, Marisa A; Cleuren, Audrey C; Hobbs, Linzi M; Mishack, Lena M; Johnston, Alexander J; Kotnik, Emilee; Siemieniak, David R; Xu, Jishu; Li, Jun Z; Saunders, Thomas L; Ginsburg, David

    2017-09-05

    Factor V Leiden ( F5 L ) is a common genetic risk factor for venous thromboembolism in humans. We conducted a sensitized N -ethyl- N -nitrosourea (ENU) mutagenesis screen for dominant thrombosuppressor genes based on perinatal lethal thrombosis in mice homozygous for F5 L ( F5 L/L ) and haploinsufficient for tissue factor pathway inhibitor ( Tfpi +/- ). F8 deficiency enhanced the survival of F5 L/L Tfpi +/- mice, demonstrating that F5 L/L Tfpi +/- lethality is genetically suppressible. ENU-mutagenized F5 L/L males and F5 L/+ Tfpi +/- females were crossed to generate 6,729 progeny, with 98 F5 L/L Tfpi +/- offspring surviving until weaning. Sixteen lines, referred to as "modifier of Factor 5 Leiden ( MF5L1-16 )," exhibited transmission of a putative thrombosuppressor to subsequent generations. Linkage analysis in MF5L6 identified a chromosome 3 locus containing the tissue factor gene ( F3 ). Although no ENU-induced F3 mutation was identified, haploinsufficiency for F3 ( F3 +/- ) suppressed F5 L/L Tfpi +/- lethality. Whole-exome sequencing in MF5L12 identified an Actr2 gene point mutation (p.R258G) as the sole candidate. Inheritance of this variant is associated with suppression of F5 L/L Tfpi +/- lethality ( P = 1.7 × 10 -6 ), suggesting that Actr2 p.R258G is thrombosuppressive. CRISPR/Cas9 experiments to generate an independent Actr2 knockin/knockout demonstrated that Actr2 haploinsufficiency is lethal, supporting a hypomorphic or gain-of-function mechanism of action for Actr2 p.R258G Our findings identify F8 and the Tfpi/F3 axis as key regulators in determining thrombosis balance in the setting of F5 L and also suggest a role for Actr2 in this process.

  4. Orthopterological notes I : On the Lesini of the Leiden Museum (Tettigoniidae, Copiphorinae)

    NARCIS (Netherlands)

    Jong, de C.

    1942-01-01

    When rearranging a part of the collections of Orthoptera in the Rijksmuseum van Natuurlijke Historie at Leiden I found a number of specimens belonging to this tribus, which by former authors is considered as a separate subfamily with the name Eumegalodontinae (Kirby, 1906, p. 289; Caudell, 1927, p.

  5. Increased sperm count may account for high population frequency of factor V Leiden

    NARCIS (Netherlands)

    Cohn, D. M.; Repping, S.; Büller, H. R.; Meijers, J. C. M.; Middeldorp, S.

    2010-01-01

    Background: Factor V Leiden (FVL) increases the risk of venous thrombosis and pregnancy loss in carriers. Nevertheless, this relatively old mutation is prevalent in Caucasion populations, which could be explained by positive selection pressure. Men with FVL have previously been found to have higher

  6. CETP does not affect triglyceride production or clearance in APOE*3-Leiden mice

    NARCIS (Netherlands)

    Bijland, S.; Berg, S.A.A. van den; Voshol, P.J.; Hoek, A.M. van den; Princen, H.M.G.; Havekes, L.M.; Rensen, P.C.N.; Dijk, K.W. van

    2010-01-01

    The cholesteryl ester transfer protein (CETP) facilitates the bidirectional transfer of cholesteryl esters and triglycerides (TG) between HDL and (V)LDL. By shifting cholesterol in plasma from HDL to (V)LDL in exchange for VLDL-TG, CETP aggravates atherosclerosis in hyperlipidemic APOE*3-Leiden

  7. Die Leiden des jungen Werthers: Den unge Werthers lidelser

    OpenAIRE

    Wibe, Henriette Nøddebo; Mathiassen, Jonas Bundgaard; Villadsen, Line Møgelvang; Aeppli, Jon Marius Brogaard; Hvidtfeldt, Sidi Sami Idrissi; Jakobsen, Mathias Simonsen

    2013-01-01

    This project investigate the philosophical influence of Jean-Jaques Rousseau’s Discours sur I’origine et les fondemens de I’inégalité parmi les hommes on Johann Wolfgang von Goethe’s Die Leiden des jungen Werthers. The concepts of the natural and conscious man that are set forth in the second Discours are compared to Werthers dualistic selfhood and the influence this has on the understanding of the narrative of Werther. Furthermore the project assesses the extent to which the revised 1787 ver...

  8. Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor

    NARCIS (Netherlands)

    Dijk, K.W. van; Vlijmen, B.J.M. van; Zee, A. van der; Hof, B. van 't; Boom, H. van der; Kobayashi, K.; Chan, L.; Havekes, L.M.; Hofker, M.H.

    1998-01-01

    We have investigated the interaction of apolipoprotein E2(Arg158- Cys) (apoE2) and apolipoprotein E3Leiden (apoE3-Leiden) with the very low density lipoprotein (VLDL) receptor in vivo and in vitro to define the possible role of this receptor in lipoprotein metabolism and atherosclerosis. The in vivo

  9. Subacute Budd-Chiari syndrome associated with polycythemia vera and factor V Leiden mutation

    NARCIS (Netherlands)

    Simsek, S; Verheesen, RV; Haagsma, EB; Lourens, J

    We describe a 48-year-old caucasian woman with a subacute Budd-Chiari syndrome attributed to the presence of polycythaemia vera, heterozygosity for the factor V Leiden mutation and the use of an oral contraceptive pill. Two diagnostic pitfalls were encountered. First, on CT scanning of the abdomen

  10. Plasma hepcidin levels and anemia in old age. The Leiden 85-Plus Study

    NARCIS (Netherlands)

    Elzen, W.P. den; Craen, A.J. de; Wiegerinck, E.T.G.; Westendorp, R.G.J.; Swinkels, D.W.; Gussekloo, J.

    2013-01-01

    Hepcidin, an important regulator of iron homeostasis, is suggested to be causally related to anemia of inflammation. The aim of this study was to explore the role of plasma hepcidin in anemia among older persons from the general population. The Leiden 85-Plus Study is a population-based study of

  11. Human universe

    CERN Document Server

    Cox, Brian

    2014-01-01

    Human life is a staggeringly strange thing. On the surface of a ball of rock falling around a nuclear fireball in the blackness of a vacuum the laws of nature conspired to create a naked ape that can look up at the stars and wonder where it came from. What is a human being? Objectively, nothing of consequence. Particles of dust in an infinite arena, present for an instant in eternity. Clumps of atoms in a universe with more galaxies than people. And yet a human being is necessary for the question itself to exist, and the presence of a question in the universe - any question - is the most wonderful thing. Questions require minds, and minds bring meaning. What is meaning? I don't know, except that the universe and every pointless speck inside it means something to me. I am astonished by the existence of a single atom, and find my civilisation to be an outrageous imprint on reality. I don't understand it. Nobody does, but it makes me smile. This book asks questions about our origins, our destiny, and our place i...

  12. PXR agonism decreases plasma HDL levels in ApoE*3-Leiden.CETP mice

    NARCIS (Netherlands)

    Haan, W. de; Vries-van der Weij, J. de; Mol, I.M.; Hoekstra, M.; Romijn, J.A.; Jukema, J.W.; Havekes, L.M.; Princen, H.M.G.; Rensen, P.C.N.

    2009-01-01

    Pregnane X receptor (PXR) agonism has been shown to affect multiple steps in both the synthesis and catabolism of HDL, but its integrated effect on HDL metabolism in vivo remains unclear. The aim of this study was to evaluate the net effect of PXR agonism on HDL metabolism in ApoE*3-Leiden (E3L) and

  13. Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice.

    Directory of Open Access Journals (Sweden)

    Chunxiu Hu

    Full Text Available Lipids are known to play crucial roles in the development of life-style related risk factors such as obesity, dyslipoproteinemia, hypertension and diabetes. The first selective cannabinoid-1 receptor blocker rimonabant, an anorectic anti-obesity drug, was frequently used in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m(2 with associated risk factors such as type II diabetes and dyslipidaemia in the past. Less is known about the impact of this drug on the regulation of lipid metabolism in plasma and liver in the early stage of obesity.We designed a four-week parallel controlled intervention on apolipoprotein E3 Leiden cholesteryl ester transfer protein (ApoE*3Leiden.CETP transgenic mice with mild overweight and hypercholesterolemia. A liquid chromatography-linear ion trap-Fourier transform ion cyclotron resonance-mass spectrometric approach was employed to investigate plasma and liver lipid responses to the rimonabant intervention. Rimonabant was found to induce a significant body weight loss (9.4%, p<0.05 and a significant plasma total cholesterol reduction (24%, p<0.05. Six plasma and three liver lipids in ApoE*3Leiden.CETP transgenic mice were detected to most significantly respond to rimonabant treatment. Distinct lipid patterns between the mice were observed for both plasma and liver samples in rimonabant treatment vs. non-treated controls. This study successfully applied, for the first time, systems biology based lipidomics approaches to evaluate treatment effects of rimonabant in the early stage of obesity.The effects of rimonabant on lipid metabolism and body weight reduction in the early stage obesity were shown to be moderate in ApoE*3Leiden.CETP mice on high-fat diet.

  14. Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

    DEFF Research Database (Denmark)

    van der Spoel, Evie; Rozing, Maarten P; Houwing-Duistermaat, Jeanine J

    2015-01-01

    Reduced insulin/insulin-like growth factor 1 (IGF-1) signaling has been associated with longevity in various model organisms. However, the role of insulin/IGF-1 signaling in human survival remains controversial. The aim of this study was to test whether circulating IGF-1 axis parameters associate...... with old age survival and functional status in nonagenarians from the Leiden Longevity Study. This study examined 858 Dutch nonagenarian (males≥89 years; females≥91 years) siblings from 409 families, without selection on health or demographic characteristics. Nonagenarians were divided over sex...

  15. On some Hymenoptera from the collection of Guerin-Méneville in the Leiden museum

    NARCIS (Netherlands)

    Vecht, van der J.

    1957-01-01

    About thirty years ago, while studying the Sphecinae of the Leiden Museum, I found two species of Sphex, described by F. E. Guérin-Méneville, represented here by specimens originating from the collection of this author. A note on these species, Sphex lanierii Guérin and Sphex paulinieri Guérin, was

  16. In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 → Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice

    NARCIS (Netherlands)

    Vlijmen, B.J.M. van; Dijk, K.W. van; Hof, H.B. van 't; Gorp, P.J.J. van; Zee, A. van der; Boom, H. van der; Breuer, M.L.; Hofker, M.H.; Havekesf, L.M.

    1996-01-01

    Apolipoprotein E*2(Arg-155 → Cys) (APOE*2) transgenic mice were generated and compared to the previously generated apolipoprotein E*3- Leiden (APOE*3-Leiden) transgenic mice to study the variable expression of hyperlipoproteinemia associated with these two APOE variants. In the presence of the

  17. Plasma lipoproteins in familial dysbetalipoproteinemia associated with apolipoproteins E2 (Arg158 -->Cys), E3-Leiden, and E2 (Lys146-->Gln), and effects of treatment with simvastatin

    NARCIS (Netherlands)

    Zhao, S.P.; Smelt, A.H.; Maagdenberg, A.M. van den; Tol, A. van; Vroom T.F.; Gevers Leuven, J.A.; Frants, R.R.; Havekes, L.M.; Laarse, A. van der; Hooft, F.M. van 't

    1994-01-01

    Using a density-gradient ultracentrifugation technique, we analyzed in detail the plasma lipoprotein profiles of 18 patients with familial dysbetalipoproteinemia (FD) who had apolipoprotein (apo) E2(Arg158-->Cys) homozygosity (the E2-158 variant, n = 6), apoE3-Leiden heterozygosity (the E3-Leiden

  18. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice

    OpenAIRE

    Lisa R. Hoving; Margreet R. de Vries; Rob C. M. de Jong; Saeed Katiraei; Amanda Pronk; Paul H. A. Quax; Vanessa van Harmelen; Ko Willems van Dijk

    2018-01-01

    The prebiotic inulin has proven effective at lowering inflammation and plasma lipid levels. As atherosclerosis is provoked by both inflammation and hyperlipidemia, we aimed to determine the effect of inulin supplementation on atherosclerosis development in hypercholesterolemic APOE*3-Leiden (E3L) mice. Male E3L mice were fed a high-cholesterol (1%) diet, supplemented with or without 10% inulin for 5 weeks. At week 3, a non-constrictive cuff was placed around the right femoral artery to induce...

  19. HOW UNIVERSAL ARE THE UNIVERSAL HUMAN RIGHTS TODAY?

    Directory of Open Access Journals (Sweden)

    Lia-Alexandra BALTADOR

    2016-12-01

    Full Text Available This paper aims to contribute to a constructive debate on human rights. The two World Wars of the last century brought about the creation of the United Nations aimed “to reaffirm faith in fundamental human rights, in the dignity and worth of the human person, in the equal rights of men and women and of nations large and small”. Only three years later the Universal Declaration of the Human Rights was elaborated and promoted by the UN, considered to be the foundation of international human rights law. Today, as globalization brings all closer together in a “global village”, one can see that there are many ways to perceive and guarantee human rights, in different states, but also within different states. Poverty, illiteracy, censorship, cruel treatment and even the lack of guarantee for the right to life are, unfortunately, the norm for many people of the world. Such observations bring up questions regarding the legitimacy, universality and coherence of human rights.

  20. Ein Werther der DDR : Plenzdorfs Neue Leiden des jungen W. im gespaltenen Deutschland

    OpenAIRE

    Jäger, Georg

    2009-01-01

    Die neuen Leiden des jungen W. wurden »bewußt auf Auslegbarkeit geschrieben« und irritierten die Kritiker durch »die ungeheure Breite der Assoziationsmöglichkeiten«. Durch die vier »strukturtragenden Schichten« oder Informationsebenen des Textes kommt es zu interferierenden Perspektiven: 1. die voranstehenden Dokumente (Zeitungsnotiz, drei Todesanzeigen), 2. »die szenisch-dialogisch objektivierte Erinnerungsperspektive der Eltern und Arbeitskollegen«, 3. die Kommentare Edgars »von jenseits de...

  1. Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study

    NARCIS (Netherlands)

    Streppel, M.T.; Vries, de J.H.M.; Meyboom, S.; Beekman, M.; Craen, A.J.M.; Slagboom, P.E.; Feskens, E.J.M.

    2013-01-01

    Background - Invalid information on dietary intake may lead to false diet-disease associations. This study was conducted to examine the relative validity of the food frequency questionnaire (FFQ) used to assess dietary intake in the Leiden Longevity Study. Methods - A total of 128 men and women

  2. Charles Darwin’s lost Cinereous Harrier found in the collection of the National Museum of Natural History Leiden

    NARCIS (Netherlands)

    Grouw, van H.; Steinheimer, F.D.

    2008-01-01

    During reorganisation of the Leiden bird collection a mounted harrier was found what seemed to be one of the still lost specimens collected by Darwin. After closer research it turned out it was indeed the last missing harrier of the Darwin collection.

  3. Has one of Captain Cook’s possums landed in Leiden? The possible holotype of Pseudocheirus peregrinus (Boddaert, 1785)

    NARCIS (Netherlands)

    Smeenk, C.

    2009-01-01

    The identity of an old female specimen of Pseudocheirus peregrinus (Boddaert, 1785) in the National Museum of Natural History, Leiden, is discussed and the early descriptions and nomenclatural history of the species are reviewed. The assumption by Temminck (1824) and Jentink (1888) that the animal

  4. Factor V Leiden is associated with increased sperm count

    DEFF Research Database (Denmark)

    van Mens, T E; Joensen, U N; Bochdanovits, Z

    2017-01-01

    STUDY QUESTION: Is the thrombophilia mutation factor V Leiden (FVL) associated with an increased total sperm count? SUMMARY ANSWER: Carriers of FVL have a higher total sperm count than non-FVL-carriers, which could not be explained by genetic linkage or by observations in a FVL-mouse model. WHAT...... IS KNOWN ALREADY: FVL has a high prevalence in Caucasians despite detrimental health effects. Carriers have been shown to have higher fecundity, which might partly explain this evolutionary paradox. STUDY DESIGN, SIZE, DURATION: We determined FVL status in two cohorts (Dutch, n = 627; Danish, n = 854....... There were differences in smoking, abstinence time and age between the cohorts. We corrected for these in the primary analysis, which consisted of a mixed linear effects model, also incorporating unobjectified population differences. In public haplotype data from subjects of European descent, we explored...

  5. Republic of Letters, Academies and Scientific Societies in the 18th Century: Leiden jar and science in teaching

    Directory of Open Access Journals (Sweden)

    Wagner Tadeu Jardim

    2017-12-01

    Full Text Available In this paper, the panorama that underpins the construction of the first electric condenser, known as the Leiden Jar, will be presented. Besides, the themes about the construction of science which are relevant to be discussed in Physics classes that concerns the development of this apparatus will be pointed. For this purpose, a historical narrative was constructed from primary and secondary sources, and it was inspired by the historiographical strand called Cultural History of Science. Thus, we seek to emphasize how ways of spreading knowledge in the context of Scientific Academies, Scientific Societies and what has been called Republic of Letters in the eighteenth century, constitute substantial extra-laboratory scientific practices for an understanding of the development of the Leiden Jar. Finally, in accordance with results from researches in the area of Science Teaching, we present some thoughts upon which elements of this narrative could be taken to the classroom.

  6. The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1

    NARCIS (Netherlands)

    Jaalouk, Diana E.; Ozawa, Nfichael G.; Sun, Jessica; Lahdenranta, Johanna; Schlingemann, Reinier O.; Pasqualini, Renata; Arap, Wadih

    2007-01-01

    For two decades, the antigen recognized by the Pathologische Anatomie Leiden-Endothelium (PAL-E) monoclonal antibody, a standard vascular endothelial cell marker, has remained elusive. Here, we used a combinatorial phage display-based approach ("epitope mapping") to select peptides binding to the

  7. Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type

    DEFF Research Database (Denmark)

    Sode, Birgitte F; Allin, Kristine H; Dahl, Morten

    2013-01-01

    ABO blood type locus has been reported to be an important genetic determinant of venous and arterial thrombosis in genome-wide association studies. We tested the hypothesis that ABO blood type alone and in combination with mutations in factor V Leiden R506Q and prothrombin G20210A is associated...

  8. Macht, machinaties en musea. Jan van der Hoeven, Hermann Schlegel en hun strijd om het Rijksmuseum van natuurlijke historie te Leiden

    Directory of Open Access Journals (Sweden)

    H.L. de Jonge

    2005-01-01

    Full Text Available Might, machinations and museums. Jan van der Hoeven, Hermann Schlegel and their battle over the National Museum for Natural History in LeidenMuseums had a central place in nineteenth-century natural history. Aside from being important places for carrying out research into nature, they were also powerful vehicles for transmitting and communicating scientific knowledge. That is why, in the nineteenth century, natural history museums were frequently battlegrounds for rival scientists. Often, clashes over scientific matters were at the same time conflicts about power and space. After all, the naturalist who could get control over a museum’s collection and decide how the specimens should be classified and exhibited ultimately had the power to dictate which scientific knowledge was communicated; which story was told by a collection of specimens. This article is about the power struggle over the directorate of the National Museum of Natural History in Leiden that broke out between Jan van der Hoeven, Professor of Natural History and Comparative Anatomy at Leiden and Herman Schlegel, the museum’s chief curator. Both were rooted in very different natural historical traditions and had completely different views on the role of the museum and how the collection should be arranged and exhibited. In this article, we follow the two scientists in their attempts to gain support for their nominations. In this way, we also get a picture of nineteenth century Dutch political culture and the role scientists could play in it.

  9. Phenotypic presentation of thrombophilia in double heterozygote for factor v leiden and prothrombin 20210 G>A mutations: Case report

    Directory of Open Access Journals (Sweden)

    Nagorni-Obradović Ljudmila

    2014-01-01

    Full Text Available Physicians usually do not suspect pulmonary thromboembolism in younger patients except in those who have thrombophilia. In those latter patients some special conditions such as trauma or surgery may provoke the disease. In some adult persons, thrombophilia may still remain unrecognized, until appearance of additional conditions influence development of thrombosis. A 55-year-old Caucasian female, non-smoker, experienced sudden chest pain and hemoptysis without chest trauma. History taking revealed type 2 diabetes mellitus and hypothyroidism. She was overweight with body mass index 29.0. The review of the family history revealed that her father and mother died of brain infarction, while her 22-year-old son and 24-year-old daughter were healthy. Due to suspicion for thrombosis, multi-slice computerized tomography thorax scan was done and pulmonary embolism was diagnosed. Although without clear risk factor for thrombosis in our patient, we performed laboratory investigation for congenital thrombophilia. Genetic analysis showed double heterozygous for factor V Leiden and prothrombin 20210 G>A mutations. Congenital thrombophilia was risk factor for thrombosis in our patient but haemostatic imbalance was not previously clinically recognized. She had two pregnancies without complications. Appearance of other associative factors such as endocrine disorders - hypothyroidism and metabolic syndrome with diabetes type 2, and overweigh were additional potential triggers for clinical manifestation of pulmonary thromboembolism in her adult age. Her children underwent genetic analysis, too. The son was also double heterozygous for factor V Leiden and prothrombin 20210 G>A mutations, while daughter was heterozygous for factor V Leiden, and none had clinical signs of thrombosis. [Projekat Ministarstva nauke Republike Srbije, br. ON175081 i br. ON 175091

  10. An early 'handwritten' shell exchange catalogue of the Leiden Museum, with notes on the collectors Rethaan Macaré and Tischbein

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2013-01-01

    A ‘handwritten’ (lithographed) shell exchange catalogue of the National Museum of Natural History, Leiden (The Netherlands), dated 1850 and containing 864 nominal taxa (861 molluscs and 3 brachiopods), is discussed in the context of the history of the museum. This catalogue must have been

  11. Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen

    NARCIS (Netherlands)

    Bloemenkamp, K. W.; Rosendaal, F. R.; Helmerhorst, F. M.; Büller, H. R.; Vandenbroucke, J. P.

    1995-01-01

    Recent concern about the safety of combined oral contraceptives (OCs) with third-generation progestagens prompted an examination of data from a population-based case-control study (Leiden Thrombophilia Study). We compared the risk of deep-vein thrombosis (DVT) during use of the newest OCs,

  12. The Universal Declaration of Human Rights

    Science.gov (United States)

    Landorf, Hilary

    2012-01-01

    A study of human rights prepares students for their role as global citizens and their study of practices in the world's countries that relate to the rights of human beings. Today, when one talks of human rights it is usually with reference to the 1948 Universal Declaration of Human Rights (UDHR). It is the task of teachers to give students the…

  13. The Universal Declaration of Human Rights - Only a Foundation.

    Science.gov (United States)

    Reichert, Elisabeth

    2002-01-01

    Explains provisions contained within the Universal Declaration of Human Rights, tracing historical beginnings of human rights to 1945, detailing events after 1945 up to the adoption of the Universal Declaration of Human Rights by the United Nations, and explaining essential terminology used in describing human rights instruments that have been…

  14. University rankings in computer science

    DEFF Research Database (Denmark)

    Ehret, Philip; Zuccala, Alesia Ann; Gipp, Bela

    2017-01-01

    This is a research-in-progress paper concerning two types of institutional rankings, the Leiden and QS World ranking, and their relationship to a list of universities’ ‘geo-based’ impact scores, and Computing Research and Education Conference (CORE) participation scores in the field of computer...... science. A ‘geo-based’ impact measure examines the geographical distribution of incoming citations to a particular university’s journal articles for a specific period of time. It takes into account both the number of citations and the geographical variability in these citations. The CORE participation...... score is calculated on the basis of the number of weighted proceedings papers that a university has contributed to either an A*, A, B, or C conference as ranked by the Computing Research and Education Association of Australasia. In addition to calculating the correlations between the distinct university...

  15. Human research ethics committees in technical universities.

    Science.gov (United States)

    Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

    2014-07-01

    Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee. © The Author(s) 2014.

  16. Factor V Leiden is associated with increased sperm count.

    Science.gov (United States)

    van Mens, T E; Joensen, U N; Bochdanovits, Z; Takizawa, A; Peter, J; Jørgensen, N; Szecsi, P B; Meijers, J C M; Weiler, H; Rajpert-De Meyts, E; Repping, S; Middeldorp, S

    2017-11-01

    Is the thrombophilia mutation factor V Leiden (FVL) associated with an increased total sperm count? Carriers of FVL have a higher total sperm count than non-FVL-carriers, which could not be explained by genetic linkage or by observations in a FVL-mouse model. FVL has a high prevalence in Caucasians despite detrimental health effects. Carriers have been shown to have higher fecundity, which might partly explain this evolutionary paradox. We determined FVL status in two cohorts (Dutch, n = 627; Danish, n = 854) of consecutively included men without known causes for spermatogenic failure, and performed an individual patient data meta-analysis of these two cohorts together with one previously published (Dutch, n = 908) cohort. We explored possible biological underpinnings for the relation between sperm count and FVL, by use of a FVL-mouse model and investigations of genetic linkage. Participants were male partners of subfertile couples (two Dutch cohorts) and young men from the general population (Danish cohort): FVL carrier rate was 4.0%, 4.6% and 7.3%, respectively. There were differences in smoking, abstinence time and age between the cohorts. We corrected for these in the primary analysis, which consisted of a mixed linear effects model, also incorporating unobjectified population differences. In public haplotype data from subjects of European descent, we explored linkage disequilibrium of FVL with all known single nucleotide polymorphisms in a 1.5 MB region around the F5 gene with an R2 cutoff of 0.8. We sequenced exons of four candidate genes hypothesized to be linked to FVL in a subgroup of FVL carriers with extreme sperm count values. The animal studies consisted of never mated 15-18-week-old C57BL/J6 mice heterozygous and homozygous for FVL and wild-type mice. We compared spermatogenesis parameters (normalized internal genitalia weights, epididymis sperm content and sperm motility) between FVL and wild-type mice. Human FVL carriers have a higher total sperm

  17. Prothrombin 20210 G: a mutation and Factor V Leiden mutation in women with a history of severe preeclampsia and (H)ELLP syndrome

    NARCIS (Netherlands)

    van Pampus, M. G.; Wolf, H.; Koopman, M. M.; van den Ende, A.; Buller, H. R.; Reitsma, P. H.

    2001-01-01

    The 20210 G-A prothrombin gene variant and the Factor V Leiden mutation are mutations associated with venous thrombotic risk. The aim of our study was to assess the prevalence of these specific mutations in women with a history of preeclampsia or hemolysis elevated liver enzymes, and low platelet

  18. Die Leiden des jungen Werthers à luz da história do conceito de subjetividade

    OpenAIRE

    Silva, Felipe Vale da

    2013-01-01

    O artigo analisa os paralelos entre o retrato do 'sujeito moderno em crise' visto no romance Die Leiden des jungen Werthers de Goethe e, por outro lado, o perfil psicossocial do 'homem do sentimento' do século XVIII, fruto da cultura da Empfindsamkeit. Defendo a perspectiva de que, no romance, Goethe não apenas se utiliza do formato literário mais tradicional da Empfindsamkeit (o do romance epistolar), como também se apropria de topói e técnicas discursivas que lhe são próprias em registro ra...

  19. HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy

    Directory of Open Access Journals (Sweden)

    Zeynep Ozcan Dag

    2014-01-01

    Full Text Available Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST. Factor 5 leiden (FVL is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy.

  20. Universe, human immortality and future human evaluation

    CERN Document Server

    Bolonkin, Alexander

    2011-01-01

    This book debates the universe, the development of new technologies in the 21st century and the future of the human race. Dr Bolonkin shows that a human soul is only the information in a person's head. He offers a new unique method for re-writing the main brain information in chips without any damage to the human brain. This is the scientific prediction of the non-biological (electronic) civilization and immortality of the human being. Such a prognosis is predicated upon a new law, discovered by the author, for the development of complex systems. According to this law, every self-copying system tends to be more complex than the previous system, provided that all external conditions remain the same. The consequences are disastrous: humanity will be replaced by a new civilization created by intellectual robots (which Dr Bolonkin refers to as "E-humans" and "E-beings"). These creatures, whose intellectual and mechanical abilities will far exceed those of man, will require neither food nor oxygen to sustain their...

  1. A Prelinguistic Gestural Universal of Human Communication

    Science.gov (United States)

    Liszkowski, Ulf; Brown, Penny; Callaghan, Tara; Takada, Akira; de Vos, Conny

    2012-01-01

    Several cognitive accounts of human communication argue for a language-independent, prelinguistic basis of human communication and language. The current study provides evidence for the universality of a prelinguistic gestural basis for human communication. We used a standardized, semi-natural elicitation procedure in seven very different cultures…

  2. Basics of teaching Latin at Humanities University

    Directory of Open Access Journals (Sweden)

    Bragova Arina Mikhailovna

    2017-04-01

    Full Text Available The article reviews the goals, tasks, methods, and results of teaching Latin at Humanities University. The article points out that the basis of teaching is analytical reading with elements of discursive analysis. In Humanities University teaching is being provided through the interdisciplinary approach. The educational process includes interactive exercises, the use various forms of control, for example, lingual-didactic testing in a virtual learning environment. The results of current and final control are formed with the help of the point-rating system of assessing knowledge.

  3. Building Human Resources Management Capacity for University Research: The Case at Four Leading Vietnamese Universities

    Science.gov (United States)

    Nguyen, T. L.

    2016-01-01

    At research-intensive universities, building human resources management (HRM) capacity has become a key approach to enhancing a university's research performance. However, despite aspiring to become a research-intensive university, many teaching-intensive universities in developing countries may not have created effective research-promoted HRM…

  4. List of the primary types of social wasps (Hymenoptera: Vespidae) deposited in the Nationaal Natuurhistorisch Museum, Leiden, and the Zoölogisch Museum, Amsterdam

    NARCIS (Netherlands)

    Kojima, J.; Achterberg, van C.

    1997-01-01

    The primary types of social wasp subfamilies Vespinae, Polistinae and Stenogastrinae housed in the Nationaal Natuurhistorisch Museum in Leiden and the Zoölogisch Museum in Amsterdam are listed. Their complete label data are given unless they are available elsewhere. Lectotypes of Polistes snelleni

  5. Human Research Ethics Committees in Technical Universities

    NARCIS (Netherlands)

    Koepsell, D.R.; Brinkman, W.P.; Pont, S.C.

    2014-01-01

    Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although

  6. The Leiden/Argentine/Bonn (LAB) Survey of Galactic HI : Final data release of the combined LDS and IAR surveys with improved stray-radiation corrections

    NARCIS (Netherlands)

    Kaberla, P.M.W.; Burton, W.B.; Hartmann, L.; Arnal, E.M.; Bajaja, E.; Morras, R.; Pöppel, W.G.L.

    2005-01-01

    We present the final data release of observations of ?21-cm emission from Galactic neutral hydrogen over the entire sky, merging the Leiden/Dwingeloo Survey (LDS: Hartmann & Burton 1997, Atlas of Galactic Neutral Hydrogen) of the sky north of ? = ?30? with the Instituto Argentino de Radioastronomía

  7. What We Have Learned from San Francisco Declaration on Research Assessment and Leiden Manifesto?

    Directory of Open Access Journals (Sweden)

    Carey Ming-Li Chen

    2017-03-01

    Full Text Available In recent years, the research performance evaluation of members of the academic community conducted by government or institutions has been applied with multiple indicators and peer review, however, there are many controversies about the design and application of research evaluation indicators. This article aims to introduce the development process of San Francisco Declaration on Research Assessment (DORA and Leiden Manifesto and summarize their contents of guidelines and attempts to compare the differences between these two documents. It hopes that this article can arise the attention and reflection of research evaluation indicators and relevant issues from Taiwan academic community to reach consensus of utilization of research evaluation indicators. It will be beneficial to develop the version of declaration with local characteristics in the future.

  8. Universal Humanism – A Globalization Context is the Classroom of Unheard Options ... how to Become More Human

    Directory of Open Access Journals (Sweden)

    Tone Svetelj

    2014-04-01

    Full Text Available Within the context of multi-cultural and multi-religious society, embedded in the process of globalization, a traditional understanding of humanism offers insufficient frameworks for an adequate comprehension of human flourishing and human search for meaning. In addition, modernity frames and evaluates in many aspects insufficiently the incomparable worth of the human person. This article offers some guidelines for further philosophical, theological and pedagogical reflection on a humanism that is more suitable for our life in the process of globalization and modernity. Such humanism continually moves us toward a better comprehension of what “human” means within a universe of divergent cultures, religions, traditions, and races. This humanism is called universal humanism , based on the Greek word kaqolou , comprising both universality and wholeness. The first part of this article analyzes some of the main characteristics of humanism in the Greek and Roman contexts, which provide historical and theoretical frameworks for universal humanism. The second part justifies the relevance and usefulness of such humanism: it helps us to transcend singular cultures, nations, political systems, religions, and, by default, to discover or explore anew the meaning of the human person on a global level. The last part of this article suggests some pedagogical attitudes that will help us to embrace and remain in a dialogical relationship with all of humanity, in order to enrich our comprehension of the incomparable worth of the human person, this time from a universal perspective.

  9. Johannes Müller, Exile Memories and the Dutch Revolt: The Narrated Diaspora, 1550-1750

    Directory of Open Access Journals (Sweden)

    C.A. (Annemieke Romein

    2017-10-01

    Full Text Available Johannes Müller, Exile Memories and the Dutch Revolt: The Narrated Diaspora, 1550-1750 (Dissertation Leiden University 2014; Leiden/ Boston: Brill. 2016, 254 pp., ISBN 9789004315914.

  10. Report on a collection of Crustacea Decapoda and Stomatopoda from Turkey and the Balkans

    NARCIS (Netherlands)

    Holthuis, L.B.

    1961-01-01

    Under the auspices of Leiden University and with the financial aid of various organisations and institutions, Messrs. E. Hennipman, P. Nijhoff, C. Swennen, A. S. Tulp, W. J. M. Vader, and W. J. J. O. de Wilde, most of whom are biological students of Leiden University, made a collecting trip to

  11. Arachidonic acid/docosahexaenoic acid-supplemented diet in early life reduces body weight gain, plasma lipids, and adiposity in later life in ApoE*3 Leiden mice

    NARCIS (Netherlands)

    Wielinga, P.Y.; Harthoorn, L.F.; Verschuren, L.; Schoemaker, M.H.; Jouni, Z.E.; Tol, E.A.F. van; Kleemann, R.; Kooistra, T.

    2012-01-01

    Scope: This study addresses whether early life arachidonic acid (ARA)/docosahexaenoic acid (DHA) supplementation or eicosapentaenoic acid (EPA)/DHA (Omacor) supplementation affects body weight gain, lipid metabolism, and adipose tissue quantity and quality in later life in ApoE*3Leiden-transgenic

  12. Reconciling Universality and Particularity through a Cosmopolitan Outlook on Human Rights

    Directory of Open Access Journals (Sweden)

    Rebecca Adami

    2012-08-01

    Full Text Available Human rights are today criticized as not compatible with different cultural values and the debate has circulated around Asian values and Islamic values as in dichotomy with human rights as universal ethics (Ignatieff, 2003. The theoretical dichotomy between universality and particularity is questioned pragmatically in this paper through a historical study. The working process of drafting the Universal Declaration of Human Rights (UDHR in 1946-48, which included thousands of people, is explored as a cosmopolitan space in which individuals from different cultural contexts met to negotiate human rights through cultural narratives. The process where particular values were negotiated with universal notion on human rights resulted in a common proclamation (UDHR without a common philosophical or ideological ground. This paper puts forth a thesis that human rights discourse can work as a cosmopolitan space, in which particular value systems meet in processes characterized by conflict and cohesion. Hence human rights can be understood as a master narrative compatible with different conflicting cultural narratives (Gibson & Somers, 1994.

  13. A prelinguistic gestural universal of human communication.

    Science.gov (United States)

    Liszkowski, Ulf; Brown, Penny; Callaghan, Tara; Takada, Akira; de Vos, Conny

    2012-01-01

    Several cognitive accounts of human communication argue for a language-independent, prelinguistic basis of human communication and language. The current study provides evidence for the universality of a prelinguistic gestural basis for human communication. We used a standardized, semi-natural elicitation procedure in seven very different cultures around the world to test for the existence of preverbal pointing in infants and their caregivers. Results were that by 10-14 months of age, infants and their caregivers pointed in all cultures in the same basic situation with similar frequencies and the same proto-typical morphology of the extended index finger. Infants' pointing was best predicted by age and caregiver pointing, but not by cultural group. Further analyses revealed a strong relation between the temporal unfolding of caregivers' and infants' pointing events, uncovering a structure of early prelinguistic gestural conversation. Findings support the existence of a gestural, language-independent universal of human communication that forms a culturally shared, prelinguistic basis for diversified linguistic communication. Copyright © 2012 Cognitive Science Society, Inc.

  14. Quiggin's Rank Dependent Model. Review of Generalized Expected Utility Theory: The Rank-Dependent Model, by John Quiggin

    OpenAIRE

    Wakker, Peter

    1994-01-01

    textabstractJohn Quiggin is a professor at the centre for Economic Policy Research of the Australian National University. His research interests are decision making under risk and agricultural economics. The reviewer is an associate professor at the Medical Decision Making Unit, University of Leiden, Leiden, The Netherlands. His main interest is decision making under uncertainty.

  15. Human rights – local value or universal norm?

    Directory of Open Access Journals (Sweden)

    Grigory Gutner

    2011-03-01

    Full Text Available The article argues for the universal character of human rights. It is demonstrated that they are not of specific value of Western culture but are a universal norm. This norm is valid not only for political practices but, first of all, for the morality and practice of argumentation. Human rights are strictly correlated with Kantian Categorical Imperative and can be substantiated by means of transcendental­pragmatic argument (K.­O. Apel. The difference between values and norms are also considered. It is demonstrated that values are always subjective and arbitrary meanwhile final justification is possible for norms.  

  16. Reconciling female genital circumcision with universal human rights.

    Science.gov (United States)

    Gordon, John-Stewart

    2017-09-18

    One of the most challenging issues in cross-cultural bioethics concerns the long-standing socio-cultural practice of female genital circumcision (FGC), which is prevalent in many African countries and the Middle East as well as in some Asian and Western countries. It is commonly assumed that FGC, in all its versions, constitutes a gross violation of the universal human rights of health, physical integrity, and individual autonomy and hence should be abolished. This article, however, suggests a mediating approach according to which one form of FGC, the removal of the clitoris foreskin, can be made compatible with the high demands of universal human rights. The argument presupposes the idea that human rights are not absolutist by nature but can be framed in a meaningful, culturally sensitive way. It proposes important limiting conditions that must be met for the practice of FGC to be considered in accordance with the human rights agenda. © 2017 John Wiley & Sons Ltd.

  17. The Universal Declaration of Human Rights

    International Nuclear Information System (INIS)

    1968-01-01

    Human Rights Year, so designated by the United Nations, is now coming to an end. The full text of the Universal Declaration, proclaimed in 1946, is given as a reminder of its ideals. In 1966 Covenants for acceptance by States were drawn up and opened for signature. (author)

  18. Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: results of a case-control study

    NARCIS (Netherlands)

    Janssen, H. L.; Meinardi, J. R.; Vleggaar, F. P.; van Uum, S. H.; Haagsma, E. B.; van der Meer, F. J.; van Hattum, J.; Chamuleau, R. A.; Adang, R. P.; Vandenbroucke, J. P.; van Hoek, B.; Rosendaal, F. R.

    2000-01-01

    In a collaborative multicenter case-control study, we investigated the effect of factor V Leiden mutation, prothrombin gene mutation, and inherited deficiencies of protein C, protein S, and antithrombin on the risk of Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT). We compared 43 BCS

  19. Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis : results of a case-control study

    NARCIS (Netherlands)

    Janssen, HLA; Meinardi, [No Value; Vleggaar, FP; van Uum, SHM; Haagsma, EB; van der Meer, FJM; van Hattum, J; Chamuleau, RAFM; Adang, RP; Vandenbroucke, JP; van Hoek, B; Rosendaal, FR

    2000-01-01

    In a collaborative multicenter case-control study, we investigated the effect of factor V Leiden mutation, prothrombin gene mutation, and inherited deficiencies of protein C, protein S, and antithrombin on the risk of Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT), We compared 43 BCS

  20. Human Rights Here and Now: Celebrating the Universal Declaration of Human Rights.

    Science.gov (United States)

    Flowers, Nancy, Ed.

    Although December 10, 1998, marked the 50th anniversary of the United Nations' Universal Declaration of Human Rights (UDHR), most people living in the United States remain unaware of this document, the foundation stone of all human rights. Intended for use by both community groups and teachers in elementary and secondary schools, this educational…

  1. An early (1850) 'handwritten' shell exchange catalogue of the Leiden Museum, with notes on the collectors Rethaan Macaré and Tischbein

    OpenAIRE

    Bruggen, van, A.C.

    2013-01-01

    A ‘handwritten’ (lithographed) shell exchange catalogue of the National Museum of Natural History, Leiden (The Netherlands), dated 1850 and containing 864 nominal taxa (861 molluscs and 3 brachiopods), is discussed in the context of the history of the museum. This catalogue must have been distributed in a limited edition to shell collectors interested in the exchange of specimens. Among the exchange partners of the museum were the well-known 19th century Dutch collector Lady (later Dowager) F...

  2. Essay review: Een eeuw op zijn kop

    Directory of Open Access Journals (Sweden)

    Ad Maas

    2015-02-01

    Full Text Available Beschouwing naar aanleiding van de publicatie van (1 Andreas Weber, Hybrid ambitions. Science, governance, and empire (Leiden: Leiden University Press 2012. xi+263 pp., ISBN: 978-90-8728-1663, € 49,95; (2 Martin P.M. Weiss, The masses and the muses. A history of Teylers Museum in the nineteenth century (Dissertatie: Universiteit Leiden 2013. ix+332 pp.; (3 Hieke Huistra, Preparations on the move. The Leiden anatomical collections in the nineteenth century (Dissertatie: Universiteit Leiden 2013. ix+163 pp.; (4 P.A.J. Caljé, Student, universiteit en samenleving. De Groningse universiteit in de negentiende eeuw (Hilversum: Verloren 2009. 631 pp., ISBN: 978-90-6550-978-9, € 49,-.

  3. 76 FR 14058 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... in the possession and control of the University of Wyoming Anthropology Department, Human Remains... made by University of Wyoming, Anthropology Department, Human Remains Repository, professional staff in...

  4. China Back in the Frame. A comparative study of Canton, Whampoa and Macao harbour views in the Leiden Museum of Ethnology and in the Guangzhou Museum

    NARCIS (Netherlands)

    Poel, van der R.H.M.; Groenendijk, E.; Viallé, C.; Blussé, L.

    2009-01-01

    This article presents a brief overview of research results deriving from the investigation of a group of 18th and 19th century export oil paintings from China in the collection of the National Museum of Ethnology n Leiden. The oils were compared with a group of reverse glass paintings in the same

  5. A genetic study of Factor V Leiden (G1691A) mutation in young ischemic strokes with large vessel disease in a South Indian population.

    Science.gov (United States)

    Anadure, Ravi; Christopher, Rita; Nagaraja, Dindagur; Narayanan, Coimbatore

    2017-10-01

    Factor V Leiden (FVL) has been, by far, the most investigated gene mutation, with 26 studies to date, on its role in arterial strokes. Overall, a meta-analysis of all these studies taken together showed that carriers of the Factor V Leiden allele were 1.33times more likely to develop arterial strokes when compared to controls. We subjected a highly select subset of young strokes, with large vessel infarcts, to genetic analysis for FVL mutation and compared them with matched healthy controls to look for a statistically significant association. In this prospective study, 6/120 cases (5%) and 2/120 controls (1.6%) were positive for heterozygous FVL (G1691A) mutation. The higher prevalence of FVL mutation in cases (5%) compared to controls (1.6%) did not show statistical significance with a Pearson's Chi square P value of 0.15. The Odds Ratio (OR) for risk of large vessel disease in FVL positive cases was 3.10 (95% CI of 0.61-15.7). FVL mutation (G1691A) in young Indian subjects with ischemic strokes does not seem to be significantly associated with large vessel disease. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. The association of factor V G1961A (factor V Leiden), prothrombin G20210A, MTHFR C677T and PAI-1 4G/5G polymorphisms with recurrent pregnancy loss in Bosnian women.

    Science.gov (United States)

    Jusić, Amela; Balić, Devleta; Avdić, Aldijana; Pođanin, Maja; Balić, Adem

    2018-08-01

    Aim To investigate association of factor V Leiden, prothrombin G20210A, MTHFR C677T and PAI-1 4G/5G polymorphisms with recurrent pregnancy loss in Bosnian women. Methods A total of 60 women with two or more consecutive miscarriages before 20 weeks of gestation with the same partners and without history of known causes or recurrent pregnancy loss were included. A control group included 80 healthy women who had one or more successful pregnancies without history of any complication which could be associated with miscarriages. Genotyping of factor V Leiden, prothrombin G20210A, MTHFR C677T and PAI-1 4G/5G polymorphisms were performed by polymerase chain reaction/restriction fragments length polymorphism method (PCR/RFLP). Results Both factor V Leiden and MTHFR C677T polymorphisms were significantly associated with recurrent pregnancy loss (RPL) in Bosnian women while prothrombin G20210A and PAI-1 4G/5G polymorphisms did not show strongly significant association. Conclusion The presence of thrombophilic polymorphisms may predispose women to recurrent pregnancy loss. Future investigation should be addressed in order to find when carriers of those mutations, polymorphisms should be treated with anticoagulant therapy. Copyright© by the Medical Assotiation of Zenica-Doboj Canton.

  7. Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial

    NARCIS (Netherlands)

    de Gast-Bakker, D. H.; de Wilde, R. B. P.; Hazekamp, M. G.; Sojak, V.; Zwaginga, J. J.; Wolterbeek, R.; de Jonge, E.; Gesink-van der Veer, B. J.

    2013-01-01

    To investigate the safety and effects of a restrictive red blood cell (RBC) transfusion strategy in pediatric cardiac surgery patients. Randomized controlled trial. Pediatric ICU in an academic tertiary care center, Leiden University Medical Center, Leiden, The Netherlands. One hundred seven

  8. Cerebral infarction and femoral venous thrombosis detected in a patient with diabetic ketoacidosis and heterozygous factor V Leiden G1691A and PAI-1 4G/5G mutations.

    Science.gov (United States)

    Yaroglu Kazanci, Selcen; Yesilbas, Osman; Ersoy, Melike; Kihtir, Hasan Serdar; Yildirim, Hamdi Murat; Sevketoglu, Esra

    2015-09-01

    Cerebral infarction is one of the serious neurological complications of diabetic ketoacidosis (DKA). Especially in patients who are genetically prone to thrombosis, cerebral infarction may develop due to inflammation, dehydration, and hyperviscocity secondary to DKA. A 6-year-old child with DKA is diagnosed with cerebral infarction after respiratory insufficiency, convulsion, and altered level of consciousness. Femoral and external iliac venous thrombosis also developed in a few hours after central femoral catheter had been inserted. Heterozygous type of factor V Leiden and PAI-14G/5G mutation were detected. In patients with DKA, cerebral infarction may be suspected other than cerebral edema when altered level of consciousness, convulsion, and respiratory insufficiency develop and once cerebral infarction occurs the patients should also be evaluated for factor V Leiden and PAI-14G/5G mutation analysis in addition to the other prothrombotic risk factors.

  9. 76 FR 14057 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... Anthropology Department, Human Remains Repository, Laramie, WY. The human remains and associated funerary... the human remains was made by University of Wyoming, Anthropology Department, Human Remains Repository...

  10. Human Resources Management in Educational Faculties of State Universities in Turkey

    Science.gov (United States)

    Öztürk, Sevim

    2016-01-01

    This study aims to evaluate the human resources management in the faculties of education of state universities in Turkey within the context of Human Resources Management Principles. The study population consisted of 40 academic members in the faculties of education of 20 different state universities and 10 academic unit administrators at different…

  11. Human rights on the thin red line between universality and relativity

    Directory of Open Access Journals (Sweden)

    Avramović Dragutin

    2014-01-01

    Full Text Available Human rights represent an open legal and political concept with a very wide value variable. Academic discussions on human rights nature have mostly commenced after the World War II during the trend of human rights internationalization, reaching their climax after the Cold war. This paper examines actual theories on human rights, from those accepting them as universal, up to those marking another pole, favoring idea of absolute relativity of human rights. The author asserts that the most acceptable should be a middle solution, standing of moderate relativism or position of relative universalism of human rights. He claims that only a very limited circle of basic, 'substantial' human rights, having been accepted through an intercultural consensus, may pretend to be treated as universal. Out of that narrow sphere, there are many other human rights whose meaning and interpretation depend strongly upon concrete cultural context. The author points that in those cases it is important to respect a relativistic discourse and that the only solution should be explored within an intercultural and inter-civilizational dialogue, where non-western values should be equally treated as the western ones.

  12. On the universal structure of human lexical semantics.

    Science.gov (United States)

    Youn, Hyejin; Sutton, Logan; Smith, Eric; Moore, Cristopher; Wilkins, Jon F; Maddieson, Ian; Croft, William; Bhattacharya, Tanmoy

    2016-02-16

    How universal is human conceptual structure? The way concepts are organized in the human brain may reflect distinct features of cultural, historical, and environmental background in addition to properties universal to human cognition. Semantics, or meaning expressed through language, provides indirect access to the underlying conceptual structure, but meaning is notoriously difficult to measure, let alone parameterize. Here, we provide an empirical measure of semantic proximity between concepts using cross-linguistic dictionaries to translate words to and from languages carefully selected to be representative of worldwide diversity. These translations reveal cases where a particular language uses a single "polysemous" word to express multiple concepts that another language represents using distinct words. We use the frequency of such polysemies linking two concepts as a measure of their semantic proximity and represent the pattern of these linkages by a weighted network. This network is highly structured: Certain concepts are far more prone to polysemy than others, and naturally interpretable clusters of closely related concepts emerge. Statistical analysis of the polysemies observed in a subset of the basic vocabulary shows that these structural properties are consistent across different language groups, and largely independent of geography, environment, and the presence or absence of a literary tradition. The methods developed here can be applied to any semantic domain to reveal the extent to which its conceptual structure is, similarly, a universal attribute of human cognition and language use.

  13. Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population

    Directory of Open Access Journals (Sweden)

    Mario D’Amico

    2013-01-01

    Full Text Available Thrombophilic genetic factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A were studied as risk factors in 235 Caucasian subjects: 85 patients with abdominal thrombosis (54 with portal vein thrombosis (PVT and 31 with Budd-Chiari syndrome (BCS without liver cirrhosis or hepatocellular carcinoma and 150 blood bank donors. Seventy-five patients with PVT/BCS showed associated disease or particular clinical status (46 PVT/29 BCS: 37 myeloproliferative neoplasm (20 PVT/17 BCS, 12 abdominal surgery (10 PVT/2 BCS, 10 contraception or pregnancy (6 PVT/4 BCS, 7 abdominal acute disease (6 PVT/1 BCS, and 9 chronic disease (4 PVT/5 BCS; ten patients did not present any association (8 PVT/2 BCS. PAI-14G-4G, MTHFR677TT, and V Leiden 506Q were significantly frequent (OR 95% CI and χ2 test with P value in abdominal thrombosis; in these patients PAI-14G-4G and MTHFR677TT distributions deviated from that expected from a population in the Hardy-Weinberg equilibrium (PAI-1: χ2=13.8, P<0.001; MTHFR677: χ2=7.1, P<0.01, whereas the equilibrium was respected in healthy controls. V Leiden Q506 and Prothrombin 20210A were in the Hardy-Weinberg equilibrium both in patients with abdominal thrombosis and healthy controls. Our study shows an important role of PAI-14G-4G and MTHFR677TT in abdominal thrombosis without liver cirrhosis or hepatocellular carcinoma.

  14. Universal Declaration of Human Rights: 40th Anniversary.

    Science.gov (United States)

    Adams, Juanita, Ed.

    December 10, 1988, marks the 40th anniversary of the adoption by the United Nations of the Universal Declaration of Human Rights. The Declaration represents the first comprehensive, global statement on basic human rights, embracing many of the values long held by U.S. citizens; and it urges all peoples and all nations to promote respect for the…

  15. Twintig jaar coeliakie bij kinderen in Nederland: Meer diagnosen en een veranderde verschijningsvorm [Twenty years of childhood coeliac disease in the Netherlands: More diagnoses and changed clinical picture

    NARCIS (Netherlands)

    George, E.K.; Mearin, M.L.; Kanhai, Sh.M.; Franken, H.C.M.; Houwen, R.H.J.; Hirasing, R.A.; Vandenbroucke, J.P.

    1998-01-01

    Objective. To assess the incidence of childhood coeliac disease in the Netherlands and to study the clinical features. Design. Prospective. Setting. Leiden University Medical Centre, Leiden, the Netherlands. Method. Cases of childhood coeliac disease in the Netherlands in 1993-1995 were identified

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-03-26

    Mar 26, 2007 ... Plasticity is a crucial component of the life cycle of invertebrates that live as active ... in terms of resources, or mainly in a dry season that is more stressful. ... Leiden University, PO Box 9516, 2300 RA Leiden, The Netherlands ...

  17. Splicing modulation therapy in the treatment of genetic diseases

    Directory of Open Access Journals (Sweden)

    Arechavala-Gomeza V

    2014-12-01

    Full Text Available Virginia Arechavala-Gomeza,1 Bernard Khoo,2 Annemieke Aartsma-Rus3 1Neuromuscular Disorders Group, BioCruces Health Research Institute, Barakaldo, Bizkaia, Spain; 2Endocrinology, Division of Medicine, University College London, London, UK; 3Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands All authors contributed equally to this manuscript Abstract: Antisense-mediated splicing modulation is a tool that can be exploited in several ways to provide a potential therapy for rare genetic diseases. This approach is currently being tested in clinical trials for Duchenne muscular dystrophy and spinal muscular atrophy. The present review outlines the versatility of the approach to correct cryptic splicing, modulate alternative splicing, restore the open reading frame, and induce protein knockdown, providing examples of each. Finally, we outline a possible path forward toward the clinical application of this approach for a wide variety of inherited rare diseases. Keywords: splicing, therapy, antisense oligonucleotides, cryptic splicing, alternative splicing

  18. The Dutch constitution beyond 200 : Tradition and innovation in a multilevel legal order

    NARCIS (Netherlands)

    Franco Ferrari, Giuseppe; Passchier, Reijer; Voermans, W.J.M.

    2018-01-01

    This book covers the updated papers presented at a seminar in Leiden, the Netherlands in November 2016, which was organized by the Italian Public Comparative and European Law Association (DPCE) and the Department of Constitutional and Administrative Law of Leiden University in celebration of the

  19. Book Reviews

    OpenAIRE

    Mary Somers Heidhues; U. Wikan; Henk Schulte Nordholt; Gehan Wijeyewardene; Oscar Salemink; James J. Fox; Jerome Rousseau; H. Claessen; Ratna Saptari; Marijke Barend-van Haeften; Harry A. Poeze; Wolfgang Marschall; G.E. Marrison; H. den Hertog; A. M. Luyendijk-Elshout

    1992-01-01

    - Jet Bakels, Robert Layton, The anthropology of art. Cambridge: Cambridge University Press, 1991, 258 pp. - J.M.S. Baljon, Herman Leonard Beck, De Islam in Nederland: Romancing religion? [Inaugurele rede theologische faculteit Tilburg 14.2.1992.] Tilburg: Tilburg University Press 1992. - R.H. Barnes, J.D.M. Platenkamp, North Halmahera: Non-Austronesian Languages, Austronesian cultures?, Lecture presented to the Oosters Genootschap in Nederland at Leiden on 23 May 1989, Leiden: Oost...

  20. Revisiting Kant's universal law and humanity formulas

    NARCIS (Netherlands)

    Nyholm, S.R.

    2015-01-01

    This book offers new readings of Kant’s "universal law" and "humanity" formulations of the categorical imperative. It shows how, on these readings, the formulas do indeed turn out being alternative statements of the same basic moral law, and in the process responds to many of the standard objections

  1. Timo de Rijk : 'We plant the seed'; interview

    NARCIS (Netherlands)

    De Rijk, T.; Bonger, S.

    2013-01-01

    Art historian Timo de Rijk was appointed Professor of Design, Culture and Society in Delft and Leiden last September. He calls this combination ‘a real breakthrough’. ‘Leiden University studies the workings of culture, while TU Delft aims at creating new things. These are fundamentally different

  2. Computational Linguistics in the Netherlands 2004 : Selected papers from the fifteenth CLIN meeting

    NARCIS (Netherlands)

    Wouden, Ton van der; Poß, Michaela; Reckman, Hilke; Cremers, Crit

    2005-01-01

    This volume contains a selection of the papers presented at the fifteenth installment of Computational Linguistics in the Netherlands, held at Leiden University on Friday, December 17th, 2004. Organized by the computational linguists of what was at that time called the Leiden Centre for Linguistics

  3. The Westward Movement of Chinese Export Harbour Views : Significant Paintings with a Social Function

    NARCIS (Netherlands)

    Poel, van der R.H.M.

    2012-01-01

    Article (Chapter) in proceedings of the First Rombouts Graduate Conference Globalization and Glocalization in China, at Leiden University, held in Leiden on 6 and 7 September 2011. This article offers a closer examination of Chinese export harbour views and, in doing so, reveals that waterfronts and

  4. The Birth of the Universal Declaration of Human Rights.

    Science.gov (United States)

    Cooper, Michael

    1998-01-01

    Outlines the history of the ideals and enactment of the United Nations' Universal Declaration of Human Rights (UDHR). Includes a discussion of the origins of the concept of human rights, the impact of World War II, the role of nongovernmental organizations, and the process of drafting and adopting the UDHR. (DSK)

  5. Professionalizing a Global Social Movement: Universities and Human Rights

    Science.gov (United States)

    Suarez, David; Bromley, Patricia

    2012-01-01

    Research on the human rights movement emphasizes direct changes in nation-states, focusing on the efficacy of treaties and the role of advocacy in mitigating immediate violations. However, more than 140 universities in 59 countries established academic chairs, research centers, and programs for human rights from 1968-2000, a development that…

  6. Scaling and universality in the human voice.

    Science.gov (United States)

    Luque, Jordi; Luque, Bartolo; Lacasa, Lucas

    2015-04-06

    Speech is a distinctive complex feature of human capabilities. In order to understand the physics underlying speech production, in this work, we empirically analyse the statistics of large human speech datasets ranging several languages. We first show that during speech, the energy is unevenly released and power-law distributed, reporting a universal robust Gutenberg-Richter-like law in speech. We further show that such 'earthquakes in speech' show temporal correlations, as the interevent statistics are again power-law distributed. As this feature takes place in the intraphoneme range, we conjecture that the process responsible for this complex phenomenon is not cognitive, but it resides in the physiological (mechanical) mechanisms of speech production. Moreover, we show that these waiting time distributions are scale invariant under a renormalization group transformation, suggesting that the process of speech generation is indeed operating close to a critical point. These results are put in contrast with current paradigms in speech processing, which point towards low dimensional deterministic chaos as the origin of nonlinear traits in speech fluctuations. As these latter fluctuations are indeed the aspects that humanize synthetic speech, these findings may have an impact in future speech synthesis technologies. Results are robust and independent of the communication language or the number of speakers, pointing towards a universal pattern and yet another hint of complexity in human speech. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  7. Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study.

    Science.gov (United States)

    Rozing, Maarten P; Westendorp, Rudi G J; de Craen, Anton J M; Frölich, Marijke; de Goeij, Moniek C M; Heijmans, Bastiaan T; Beekman, Marian; Wijsman, Carolien A; Mooijaart, Simon P; Blauw, Gerard-Jan; Slagboom, P Eline; van Heemst, Diana

    2010-03-01

    To explore measures of metabolic syndrome and glucose metabolism in families with exceptional longevity. Case-control study. A university hospital in Leiden, the Netherlands. One hundred twenty-one offspring of nonagenarian siblings, who were enriched for familial factors promoting longevity, and 113 of their partners. No subject had diabetes mellitus. Prevalence of metabolic syndrome was determined according to the criteria of the Third Report of the National Cholesterol Education Program. Glucose tolerance was assessed according to a 2-hour oral glucose tolerance test. The offspring of nonagenarians siblings had a lower prevalence of metabolic syndrome (P=.03), similar body composition, lower mean fasting blood glucose levels (4.99 vs 5.16 mmol/L; P=.01), lower mean fasting insulin levels (5.81 vs 6.75 mU/L; P=.04), a higher mean homeostasis model assessment of insulin sensitivity (0.78 vs 0.65; P=.02), and a more-favorable glucose tolerance (mean area under the receiver operating characteristic curve for glucose (13.2 vs 14.3; P=.007) than their partners. No significant differences were observed between the offspring and their partners in beta-cell function (insulogenic index 13.6 vs 12.5; P=.38). Despite similar body composition, the offspring of nonagenarian siblings showed a lower prevalence of metabolic syndrome and better glucose tolerance than their partners, centralizing the role of favorable glucose metabolism in familial longevity.

  8. Die Leiden des jungen Werthers à luz da história do conceito de subjetividade

    Directory of Open Access Journals (Sweden)

    Felipe Vale da Silva

    2013-06-01

    Full Text Available O artigo analisa os paralelos entre o retrato do 'sujeito moderno em crise' visto no romance Die Leiden des jungen Werthers de Goethe e, por outro lado, o perfil psicossocial do 'homem do sentimento' do século XVIII, fruto da cultura da Empfindsamkeit. Defendo a perspectiva de que, no romance, Goethe não apenas se utiliza do formato literário mais tradicional da Empfindsamkeit (o do romance epistolar, como também se apropria de topói e técnicas discursivas que lhe são próprias em registro radicalmente heterodoxo. A argumentação nos ligará a uma dedução da visão do conceito de subjetividade moderna com que Goethe trabalha em sua fase final do Sturm und Drang, e que o situa como importante nome do discurso filosófico da modernidade.

  9. Higgs production at next-to-next-to-leading order

    Indian Academy of Sciences (India)

    Instituut-Lorentz, University of Leiden, Leiden, The Netherlands. Abstract. We describe the calculation of inclusive Higgs boson production at hadronic colliders at next-to-next-to-leading order (NNLO) in perturbative quantum chromody- namics. We have used the technique developed in ref. [4]. Our results agree with those.

  10. Recommendation on measures to safeguard freedom of expression and undistorted competition in EU trade mark law

    DEFF Research Database (Denmark)

    Minssen, Timo

    2015-01-01

    , University of Oxford, United Kingdom Christophe Geiger Associate Professor, Director General and Director of the Research Department, Centre for International Intellectual Property Studies, University of Strasbourg, France Gustavo Ghidini Professor of Intellectual Property and Competition Law, University...... Institute for Innovation and Competition, Munich, Germany Paul van der Kooij Associate Professor of Intellectual Property Law, Leiden Law School, University of Leiden, The Netherlands Annette Kur Senior Researcher, Max Planck Institute for Innovation and Competition, Munich, and Honorary Professor...... Professor of Commercial Law, University of Parma, Italy Timo Minssen Associate Professor, Centre for Information and Innovation Law, University of Copenhagen, Denmark Ansgar Ohly Professor of Civil Law, Intellectual Property and Competition Law, University of Munich, Germany Alexander Peukert Professor...

  11. In Search of a Universal Human Rights Metaphor: Moral Conversations across Differences

    Science.gov (United States)

    Gordon, Mordechai

    2018-01-01

    This article takes up the educational challenge of the framers of the Universal Declaration of Human Rights. Specifically, the author explores the question of: how can we talk about a universal conception of human rights in a way that both respects the need for cultural pluralism and the necessity to protect those rights and freedoms that all…

  12. Human language reveals a universal positivity bias.

    Science.gov (United States)

    Dodds, Peter Sheridan; Clark, Eric M; Desu, Suma; Frank, Morgan R; Reagan, Andrew J; Williams, Jake Ryland; Mitchell, Lewis; Harris, Kameron Decker; Kloumann, Isabel M; Bagrow, James P; Megerdoomian, Karine; McMahon, Matthew T; Tivnan, Brian F; Danforth, Christopher M

    2015-02-24

    Using human evaluation of 100,000 words spread across 24 corpora in 10 languages diverse in origin and culture, we present evidence of a deep imprint of human sociality in language, observing that (i) the words of natural human language possess a universal positivity bias, (ii) the estimated emotional content of words is consistent between languages under translation, and (iii) this positivity bias is strongly independent of frequency of word use. Alongside these general regularities, we describe interlanguage variations in the emotional spectrum of languages that allow us to rank corpora. We also show how our word evaluations can be used to construct physical-like instruments for both real-time and offline measurement of the emotional content of large-scale texts.

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2005-01-01

    Full Text Available -Monika Arnez, Niels Mulder, Southeast Asian images; Towards civil society? Chiang Mai: Silkworm Books, 2003, ix + 253 pp. -Adriaan Bedner, Connie Carter, Eyes on the prize; Law and economic development in Singapore. The Hague: Kluwer Law International, xviii + 307 pp. [The London-Leiden series on law, administration and development 7.] -Amrit Gomperts, J.R. van Diessen ,Grote atlas van Nederlands Oost-Indië/Comprehensive atlas of the Netherlands East Indies. Zierikzee: Asia Maior, Utrecht: Koninklijk Nederlands Aardrijkskundig Genootschap (KNAG, 2004, 480 pp. (editors, with the collaboration of R.C.M. Braam, W. Leijnse, P.A. Levi, J.J. Reijnders, R.P.G.A. Voskuil and M.P.B. Ziellemans, F.J. Ormeling (eds -Stuart R. Harrop, Adriaan Bedner ,Towards integrated environmental law in Indonesia? Leiden: Research school CNWS, School of Asian, African and Amerindian studies, 2003, 161 pp. [CNWS publications 127.], Nicole Niessen (eds -David Henley, Paul H. Kratoska ,Locating Southeast Asia: Geographies of knowledge and politics of space. Singapore: Singapore University Press, 2005, xi + 326 pp., Remco Raben, Henk Schulte Nordholt (eds -Gerry van Klinken, Anthony J. Langlois, The politics of justice and human rights; Southeast Asia and universalist theory. Cambridge: Cambridge University Press, 2001, xi + 214 pp. [Cambridge Asia-Pacific studies.] -Koh Keng We, Jurrien van Goor, Prelude to colonialism; The Dutch in Asia. Hilversum: Verloren, 2004, 127 pp. -Lim Beng Soon, Thomas H. Slone, Prokem; An analysis of a Jakartan slang. Oakland: Masalai Press, 2003, 95 pp. -Lim Beng Soon, Neil Khor Jin Keong ,The Penang Po Leung Kuk; Chinese women, prostitution and a welfare organisation. Kuala Lumpur; The Malaysian branch of the Royal Asiatic society (MBRAS, 2004, VII + 181 pp., Khoo Keat Siew (eds -Dick van der Meij, J. Thomas Lindblad ,Macht en majesteit; Opstellen voor Cees Fasseur bij zijn afscheid als hoogleraar in de geschiedenis van Indonesië aan de

  14. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice.

    Science.gov (United States)

    Hoving, Lisa R; de Vries, Margreet R; de Jong, Rob C M; Katiraei, Saeed; Pronk, Amanda; Quax, Paul H A; van Harmelen, Vanessa; Willems van Dijk, Ko

    2018-02-03

    The prebiotic inulin has proven effective at lowering inflammation and plasma lipid levels. As atherosclerosis is provoked by both inflammation and hyperlipidemia, we aimed to determine the effect of inulin supplementation on atherosclerosis development in hypercholesterolemic APOE*3-Leiden ( E3L ) mice. Male E3L mice were fed a high-cholesterol (1%) diet, supplemented with or without 10% inulin for 5 weeks. At week 3, a non-constrictive cuff was placed around the right femoral artery to induce accelerated atherosclerosis. At week 5, vascular pathology was determined by lesion thickness, vascular remodeling, and lesion composition. Throughout the study, plasma lipids were measured and in week 5, blood monocyte subtypes were determined using flow cytometry analysis. In contrast to our hypothesis, inulin exacerbated atherosclerosis development, characterized by increased lesion formation and outward vascular remodeling. The lesions showed increased number of macrophages, smooth muscle cells, and collagen content. No effects on blood monocyte composition were found. Inulin significantly increased plasma total cholesterol levels and total cholesterol exposure. In conclusion, inulin aggravated accelerated atherosclerosis development in hypercholesterolemic E3L mice, accompanied by adverse lesion composition and outward remodeling. This process was not accompanied by differences in blood monocyte composition, suggesting that the aggravated atherosclerosis development was driven by increased plasma cholesterol.

  15. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice

    Directory of Open Access Journals (Sweden)

    Lisa R. Hoving

    2018-02-01

    Full Text Available The prebiotic inulin has proven effective at lowering inflammation and plasma lipid levels. As atherosclerosis is provoked by both inflammation and hyperlipidemia, we aimed to determine the effect of inulin supplementation on atherosclerosis development in hypercholesterolemic APOE*3-Leiden (E3L mice. Male E3L mice were fed a high-cholesterol (1% diet, supplemented with or without 10% inulin for 5 weeks. At week 3, a non-constrictive cuff was placed around the right femoral artery to induce accelerated atherosclerosis. At week 5, vascular pathology was determined by lesion thickness, vascular remodeling, and lesion composition. Throughout the study, plasma lipids were measured and in week 5, blood monocyte subtypes were determined using flow cytometry analysis. In contrast to our hypothesis, inulin exacerbated atherosclerosis development, characterized by increased lesion formation and outward vascular remodeling. The lesions showed increased number of macrophages, smooth muscle cells, and collagen content. No effects on blood monocyte composition were found. Inulin significantly increased plasma total cholesterol levels and total cholesterol exposure. In conclusion, inulin aggravated accelerated atherosclerosis development in hypercholesterolemic E3L mice, accompanied by adverse lesion composition and outward remodeling. This process was not accompanied by differences in blood monocyte composition, suggesting that the aggravated atherosclerosis development was driven by increased plasma cholesterol.

  16. Erratum to : Daphnia revisited: local stability and bifurcation theory for physiologically structured population models explained by way of an example (Journal of Mathematical Biology, , 61, 2, (277-318), 10.1007/s00285-009-0299-y)

    NARCIS (Netherlands)

    Diekmann, Odo; Gyllenberg, Mats; Metz, J. A.J.; Nakaoka, Shinji; de Roos, André M.

    2017-01-01

    In the original publication, the addresses of the authors Dr. J.A.J. Metz and Dr. S. Nakaoka were incorrectly published. The correct address list for the authors are: J.A.J. Metz: Institute of Biology and Institute of Mathematics, Leiden University, P.O. Box 9516, 2300RA Leiden, The Netherlands. S.

  17. Global-minded Human Resources and Expectations for Universities

    Science.gov (United States)

    Inoue, Hiroshi

    Under the globalized economy, Japanese corporations compete with rivals of the western countries and emerging economies. And domestically, they face with deflation, falling birth-rate, an aging society, and shrinking market. So they need to foster and retain global-minded human resources who can play an active role in global business, and who can drive innovation. What Japanese corporations expect for global-minded human resources are ability to meet challenges, ability to think independently free from conventional wisdom, communication skills in foreign languages, interests in foreign cultures and different values, and so on. In order to foster global-minded human resources, Keidanren work with the 13 universities selected under the Japanese Government‧s “Global 30” projects to undertake “Global-minded Human Resources Development Projects” .

  18. The United States and the universality of human rights.

    Science.gov (United States)

    Chomsky, N

    1999-01-01

    The United States takes a highly relativistic stance toward the Universal Declaration of Human Rights. It regards the socio-economic rights and the right to development as without status; exempts itself from all provisions of the Declaration by failing to sign the conventions designed to implement these provisions; and unilaterally qualifies its support of civil and political rights. Leading recipients of U.S. aid have traditionally included regimes with atrocious human rights records. Those struggling for human rights should have no illusions about the systems of power and their servants.

  19. Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study

    DEFF Research Database (Denmark)

    Benfield, Thomas; Ejrnæs, Karen; Juul, Klaus

    2010-01-01

    ABSTRACT: INTRODUCTION: Disturbance of the pro-coagulatant and anti-coagulant balance is associated with a poor outcome from critical illness. The objective of this study is to determine whether the Factor V Leiden (FVL) mutation is associated with susceptibility to or death from critical illness....... METHODS: A genetic association study involving four case cohorts comprising two Gram negative sepsis, one invasive pneumococcal disease and one intensive care unit cohort with a total of 1,249 patients. Controls were derived from a population-based cohort study (N = 8,147). DNA from patients and controls...... not appear to increase the risk of admission due to severe invasive infections. Nevertheless, in the subgroup of patients admitted to intensive care an increased risk and a poorer long-term outcome for individuals with critical illness were observed for FVL mutation carriers....

  20. Blood group AB and factor V Leiden as risk factors for pre-eclampsia: a population-based nested case-control study.

    Science.gov (United States)

    Hiltunen, Leena M; Laivuori, Hannele; Rautanen, Anna; Kaaja, Risto; Kere, Juha; Krusius, Tom; Paunio, Mikko; Rasi, Vesa

    2009-06-01

    Pre-eclampsia is an important cause of maternal morbidity and mortality. Its etiology is still unknown. Clinical symptoms correlate with activation of coagulation and inherited thrombophilia has been associated with pre-eclampsia. ABO blood group has been associated with thrombotic disorders and pre-eclampsia. We assessed ABO blood group, seven thrombophilia associated polymorphisms, and anti-beta2-glycoprotein I antibodies as risk factors for pre-eclampsia. We performed a population-based nested case-control study of 100,000 consecutive pregnancies in Finland. Cases and controls were identified by combining national registers and medical records were reviewed. We studied 248 cases fulfilling strict criteria for pre-eclampsia and 679 controls. Severe pre-eclampsia, early pre-eclampsia, and pre-eclampsia with intra-uterine growth restriction (IUGR) were analyzed separately. Blood group AB increased the risk for pre-eclampsia as a whole (OR 2.1, 95% CI 1.3-3.5), and in the three subgroups (OR 2.3, 3.8, 3.4; 95% CI 1.3-3.9, 2.0-7.1, 1.6-7.1). FV Leiden increased the risk as a whole (OR 1.7, 95% CI 0.8-3.9), and in the three subgroups, although not statistically significantly. Anti-beta2-glycoprotein I antibodies were not associated with pre-eclampsia. High body mass index, diabetes, first pregnancy, and twin pregnancy increased the risk from 1.5-fold to 8.2-fold. Our results confirm and extend the prior observation of blood group AB being a risk factor for pre-eclampsia. ABO blood group is known from all pregnant women. The value of blood group as risk factor for pre-eclampsia should be further assessed in prospective studies. In this study, FV Leiden was not statistically significant risk factor.

  1. Medical humanities and philosophy: is the universe expanding or contracting?

    Science.gov (United States)

    Stempsey, William E

    2007-12-01

    The question of whether the universe is expanding or contracting serves as a model for current questions facing the medical humanities. The medical humanities might aptly be described as a metamedical multiverse encompassing many separate universes of discourse, the most prominent of which is probably bioethics. Bioethics, however, is increasingly developing into a new interdisciplinary discipline, and threatens to engulf the other medical humanities, robbing them of their own distinctive contributions to metamedicine. The philosophy of medicine considered as a distinct field of study has suffered as a result. Indeed, consensus on whether the philosophy of medicine even constitutes a legitimate field of study is lacking. This paper presents an argument for the importance of a broad conception of the philosophy of medicine and the central role it should play in organizing and interpreting the various fields of study that make up the metamedical multiverse.

  2. The human touch our part in the creation of a Universe

    CERN Document Server

    Frayn, Michael

    2007-01-01

    MF will talk about his new book The Human Touch, in which he argues that our understanding of the universe is based upon a paradox. On the one hand, we all agree that humankind is a tiny and insignificant local anomaly. On the other hand, it is impossible to have any concept of the universe except through the constructions that human beings have placed upon it. Without human beings there would be no words or language. Would there still be numbers, if there were no one to count them? Or scientific laws, if there were no words or numbers in which to express them? Would the universe even be vast, without the very fact of our smallness and insignificance to give it scale? Could it have any expression in space and time at all, except in relation to our being where we are when we are? Some of these questions are no longer purely abstract, but are becoming of practical interest to cosmologists and physicists. About the speaker: Michael Frayn is the acclaimed author of Copenhagen, the theatre play that describes Heis...

  3. Human rights & intellectual property for universal access to new essential medicines

    NARCIS (Netherlands)

    Perehudoff, Katrina; 't Hoen, Elisabeth; Babar, Zaheer

    2018-01-01

    This chapter illustrates how human rights principles can help governments, even those with the most modest budgets, scale-up universal access to expensive essential medicines. The key message is that governments have legally binding human rights obligations to immediately take steps to provide

  4. Human Rights and the Political Economy of Universal Health Care

    Science.gov (United States)

    2016-01-01

    Abstract Health system financing is a critical factor in securing universal health care and achieving equity in access and payment. The human rights framework offers valuable guidance for designing a financing strategy that meets these goals. This article presents a rights-based approach to health care financing developed by the human right to health care movement in the United States. Grounded in a human rights analysis of private, market-based health insurance, advocates make the case for public financing through progressive taxation. Financing mechanisms are measured against the twin goals of guaranteeing access to care and advancing economic equity. The added focus on the redistributive potential of health care financing recasts health reform as an economic policy intervention that can help fulfill broader economic and social rights obligations. Based on a review of recent universal health care reform efforts in the state of Vermont, this article reports on a rights-based public financing plan and model, which includes a new business tax directed against wage disparities. The modeling results suggest that a health system financed through equitable taxation could produce significant redistributive effects, thus increasing economic equity while generating sufficient funds to provide comprehensive health care as a universal public good. PMID:28559677

  5. The University Council for Workforce and Human Resource Education: Its History, Purpose, and Activities

    Science.gov (United States)

    Johnson, Scott D.; Martinez, Reynaldo L., Jr.

    2009-01-01

    This article features the University Council for Workforce and Human Resource Education, a nonprofit organization representing leading United States universities that offer graduate programs in career and technical education (CTE) and human resource development (HRD). The mission of the Council is to be a recognized force in shaping the future of…

  6. Exploring the Role of Human Capital Management on Organizational Success: Evidence from Public Universities

    Directory of Open Access Journals (Sweden)

    Odunayo Paul SALAU

    2016-12-01

    Full Text Available The demand for higher education in Nigeria has been considered as not only an investment in human capital, but also a pre-requisite for economic development. Consequent upon the expansion of higher education in Nigeria, quite a number of institutions have suffered decay due to poor work environments, inadequate educational facilities and poor funding which have resulted into unabated brain drain, strike and turnover. However, the need to develop talents is no longer hidden, what remains controversial is knowing the best method for managing human capacity especially in Nigerian State owned universities. Thus, this study examined the relationship between human capital management and organizational success using three State owned universities in Southwest, Nigeria. These universities (Ekiti State University (EKSU, Lagos State University (LASU, Tai Solarin University of Education (TASUED were chosen for their uniqueness. Survey research design was adopted with 398 respondents (staff. Self-administered questionnaire was adopted and analyzed with the adoption of Structural Equation Modelling (SEM. However, the results indicated that adequate leadership practices; learning capacity; workforce optimization; knowledge accessibility; workplace culture and; mentorship are significant predictors of organizational success in higher education.

  7. Cultural variation is part of human nature : Literary universals, context-sensitivity, and "shakespeare in the bush".

    Science.gov (United States)

    Sugiyama, Michelle Scalise

    2003-12-01

    In 1966, Laura Bohannan wrote her classic essay challenging the supposition that great literary works speak to universal human concerns and conditions and, by extension, that human nature is the same everywhere. Her evidence: the Tiv of West Africa interpret Hamlet differently from Westerners. While Bohannan's essay implies that cognitive universality and cultural variation are mutually exclusive phenomena, adaptationist theory suggests otherwise. Adaptive problems ("the human condition") and cognitive adaptations ("human nature") are constant across cultures. What differs between cultures is habitat: owing to environmental variation, the means and information relevant to solving adaptive problems differ from place to place. Thus, we find differences between cultures not because human minds differ in design but largely because human habitats differ in resources and history. On this view, we would expect world literature to express both human universals and cultural particularities. Specifically, we should expect to find literary universality at the macro level (e.g., adaptive problems, cognitive adaptations) and literary variation at the micro level (e.g., local solutions to adaptive problems).

  8. Human rights from the grassroots up: Vermont's campaign for universal health care.

    Science.gov (United States)

    McGill, Mariah

    2012-06-15

    In 2008, the Vermont Workers' Center launched the "Healthcare Is a Human Right Campaign," a grassroots campaign to secure the creation of a universal health care system in Vermont. Campaign organizers used a human rights framework to mobilize thousands of voters in support of universal health care. In response to this extraordinary grassroots effort, the state legislature passed health care legislation that incorporates human rights principles into Vermont law and provides a framework for universal health care. The United States has often lagged behind other nations in recognizing economic, social, and cultural (ESC) rights, including the right to health. Nonetheless, activists have begun to incorporate ESC rights into domestic advocacy campaigns, and state and local governments are beginning to respond where the federal government has not. Vermont serves as a powerful example of how a human rights framework can inform health care policy and inspire grassroots campaigns in the United States. This three-part article documents the Vermont Workers' Center campaign and discusses the impact that human rights activity at the grassroots level may have on attitudes towards ESC rights in the United States. The first part describes the Vermont health care crisis and explains why the center adopted international human rights principles for their campaign. The article then goes on to discuss the three-year campaign and analyze the health care reform bill that the Vermont legislature passed. Finally, the article discusses the campaign's local and national impact. Copyright © 2012 McGill.

  9. Imagination and the Humanities in Honors across the Disciplines at a Jesuit University

    Science.gov (United States)

    Kraus, Joe

    2015-01-01

    Not every student has done honors work in the humanities, but all students experience research at a human level that necessarily recalls the work of the humanities. This article describes how Joe Kraus, a professor of literature at the University of Scranton, was inspired to see applied humanities in stories of human experiences, which helped him…

  10. Maintaining excellence in teaching of human anatomy: University of ...

    African Journals Online (AJOL)

    Measures to address these challenges have resulted in wide disparities in curriculum design teaching methods, number and composition of instructors. Inspite of the challenges, the Department of Human Anatomy of the University of Nairobi (UON) maintained excellence of teaching for over 40yrs. This article describes the ...

  11. Statistical universals reveal the structures and functions of human music.

    Science.gov (United States)

    Savage, Patrick E; Brown, Steven; Sakai, Emi; Currie, Thomas E

    2015-07-21

    Music has been called "the universal language of mankind." Although contemporary theories of music evolution often invoke various musical universals, the existence of such universals has been disputed for decades and has never been empirically demonstrated. Here we combine a music-classification scheme with statistical analyses, including phylogenetic comparative methods, to examine a well-sampled global set of 304 music recordings. Our analyses reveal no absolute universals but strong support for many statistical universals that are consistent across all nine geographic regions sampled. These universals include 18 musical features that are common individually as well as a network of 10 features that are commonly associated with one another. They span not only features related to pitch and rhythm that are often cited as putative universals but also rarely cited domains including performance style and social context. These cross-cultural structural regularities of human music may relate to roles in facilitating group coordination and cohesion, as exemplified by the universal tendency to sing, play percussion instruments, and dance to simple, repetitive music in groups. Our findings highlight the need for scientists studying music evolution to expand the range of musical cultures and musical features under consideration. The statistical universals we identified represent important candidates for future investigation.

  12. Our cosmic future : humanity's fate in the universe

    Science.gov (United States)

    Prantzos, Nikos

    2000-04-01

    What is humankind's ultimate fate and destiny in the Universe? Can human life and intelligence go on forever? This captivating and unparalleled book explores the future of the human race in the Universe, for centuries, millennia, and eons to come. Nikos Prantzos, distinguished astrophysicist and popular science writer, focuses not on what will be done, but on what could be done in light of our current knowledge and the speculations of eminent scientists. While he employs many concepts from physics, Prantzos also provides historical accounts of such ideas as terraforming, asteroid mining, interstellar travel, astroengineering, and eschatology, discussing their philosophical and social implications. Moreover, he uses the work of well known science and science-fiction writers--including Verne, Wells, Clarke, Tsiolkovsky, and Dyson--to illustrate many possibilities and concepts. Our Cosmic Future offers compelling answers to such intriguing questions as: Should we return to the Moon and eventually colonize Mars and other planets in our solar system? Why haven't we encountered an extraterrestrial civilization up to this time in our history? How can we avoid various cosmic threats, such as asteroid collisions and supernova explosions? Could we escape the remote, yet certain, death of the Sun? What will eventually happen to stars, our Galaxy, distant galaxies, and the Universe itself? With its artful blend of historical, scientific accounts and themes from classic works of science fiction, Our Cosmic Future is a spellbinding work that will enchant all readers interested in space travel and colonization, cosmology, and humankind's future prospects in the Cosmos.

  13. Increase of Universality in Human Brain during Mental Imagery from Visual Perception

    OpenAIRE

    Bhattacharya, Joydeep

    2009-01-01

    BACKGROUND: Different complex systems behave in a similar way near their critical points of phase transitions which leads to an emergence of a universal scaling behaviour. Universality indirectly implies a long-range correlation between constituent subsystems. As the distributed correlated processing is a hallmark of higher complex cognition, I investigated a measure of universality in human brain during perception and mental imagery of complex real-life visual object like visual art. METHODO...

  14. International Cooperation of Izmail State University for Humanities in 2015-2016

    Directory of Open Access Journals (Sweden)

    Mykola Kapliienko

    2016-05-01

    Full Text Available The article presents the state and perspectives of international cooperation of Izmail State University for Humanities with academic partners abroad. Special attention is given to the participation of the University in European research networks for educational and curricula quality promotion, as well as to improvement of academic staff professional qualification in view of social and regional needs for sustainable economic and social development.

  15. Behavioral Response Research Evaluation Workshop (BRREW)

    Science.gov (United States)

    2015-09-30

    Len Thomas & Catriona Harris Centre for Research into Ecological and Environmental Modelling (CREEM) University of St Andrews St Andrews , UK...Specifically Dr. Hans Slabbekoorn (University of Leiden), Professor Vincent Janik (University of St Andrews ) and Professor Douglas Wartzok (Florida

  16. Assessing the Impact of Arts and Humanities Research at the University of Cambridge. Technical Report

    Science.gov (United States)

    Levitt, Ruth; Celia, Claire; Diepeveen, Stephanie; Chonaill, Siobhan Ni; Rabinovich, Lila; Tiessen, Jan

    2010-01-01

    This project for the University of Cambridge and the Arts and Humanities Research Council (AHRC) assesses the impacts of arts and humanities research at the University of Cambridge. Evidence from interviews, a survey of research staff and detailed case studies indicates that these disciplines already have a broad range of impacts. Many of these…

  17. 75 FR 5108 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Science.gov (United States)

    2010-02-01

    ... Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park Service... funerary objects in the possession and control of the University of Wyoming, Anthropology Department, Human... of Wyoming, Anthropology Department, Human Remains Repository professional staff in consultation with...

  18. Learning History through the Universal Declaration of Human Rights

    Science.gov (United States)

    Landorf, Hilary; Pineda, Martha Fernanda

    2007-01-01

    Although adolescent students often do not have knowledge of specific laws, they usually have a keen sense of justice and fairness. In this article, the author discusses the Universal Declaration of Human Rights (UDHR) as a powerful tool to channel students' sense of fairness into visible actions. Adopted in December 1948 by the General Assembly of…

  19. Wer sich den Göttern widersetzt, der stirbt jung : Untersuchung der Unvermeidbarkeit des Suizids in Die Leiden des jungen Werthers hinsichtlich der Strömung des „Sturm und Drang“

    OpenAIRE

    Andersson, Rasmus

    2015-01-01

    Der Ausgang des Romans Die Leiden des Jungen Werther (1774, von Johann Wolfgang von Goethe) wird beim ersten Anblick oft als tragische Folge einer unglücklichen und unerwiderten Liebe zu Lotte angesehen. In dieser vorliegenden Arbeit wird der weit erforschten Frage der Unvermeidbarkeit des Suizids im Werk eine alternative Deutung geliefert. Diese ist außerhalb des Romans angesiedelt, und zeigt, dass der Suizid schon in der Epoche angelegt ist.

  20. Going Dutch: Higher Education in the Netherlands

    Science.gov (United States)

    Law, David

    2016-01-01

    This article outlines some of the policy issues currently faced by research-based universities in the Netherlands. The focus is on four leading universities (University of Amsterdam: UvA; Free University of Amsterdam: VU; Leiden University; and Delft University of Technology: TUD). The author visited these institutions as part of a Study Tour…

  1. Thromboembolic events in Fabry disease and the impact of factor V Leiden.

    Science.gov (United States)

    Lenders, Malte; Karabul, Nesrin; Duning, Thomas; Schmitz, Boris; Schelleckes, Michael; Mesters, Rolf; Hense, Hans-Werner; Beck, Michael; Brand, Stefan-Martin; Brand, Eva

    2015-03-10

    Although several reports suggest an increased thromboembolic event rate, especially regarding strokes and TIAs at early age in patients with Fabry disease (FD), the risk for patients with FD to experience these events, the clinical relevance of additional risk factors including the concurrence of factor V Leiden (FVL), and the benefit of enzyme replacement therapy (ERT) regarding these events remain unclear. Three hundred four consecutively recruited patients with FD were evaluated for their lifetime occurrence of thromboembolic events such as stroke, TIA, deep vein thrombosis, and pulmonary embolism. The thromboembolic risk was determined in patients with FD and concurrent FVL, and the impact of ERT was assessed. The 304 patients with FD had a median age of 41 years and 53 (17.4%) had experienced at least one thromboembolic event during their lifetime. Among 226 patients with FD screened for FVL, 16 gene carriers were identified (7.1%). The occurrence of thromboembolic events in patients with FD and concurrent FVL was significantly increased compared to those without FVL (hazard ratio = 5.45, 95% confidence interval 2.29-12.99; p risk of thromboembolic events compared to those without ERT (hazard ratio = 0.362, 95% confidence interval 0.132-0.992; p = 0.0422). This observational study confirms that patients with FD have a high risk of clinically relevant thromboembolic events, which could be aggravated by a concurrence of FVL. ERT might be of benefit in preventing vascular events in patients with FD. The latter observation needs confirmation, however, by randomized and controlled clinical trials. © 2015 American Academy of Neurology.

  2. Right to Development and Right to the City : A Proposal of Human Rights Categories Universal as assumptions Citizenship

    Directory of Open Access Journals (Sweden)

    Alessandra Danielle Carneiro dos Santos Hilário

    2016-05-01

    Full Text Available This article discusses the Right to the City, in a conceptual dimension and wide, and his dialectical relationship with the Universal Declaration of Human Rights of 1948 and its universalism and cultural relativism categories. The Right to the City (RtC is capitula- ted as one of the categories of the Human Right to Development from the compartments on Human Rights to descend from the Universal Declaration of Human Rights. Linked to this assumption, the discussion of universalism and cultural relativism theories bring to the fore important questions and considerations as to RtC condition, since in its current design and trampled by an evil legacy of neoliberalism, this right has demonstrated the need for authoritative action of the State, given the nature of fundamental human right of the third dimension. Through RtC, boasts up of economic, social and cultural rights, requiring a positive action of the state as compliance guarantee this human right. In this bias, relevant are discussions about the concept of law, morality, liberalism, effectiveness and universality of human rights theories and cultural relativism in dialectic with the RtC and its complexity. It starts from the assumption that the Universal Declaration of Human Rights and other statements which have descended universality (despite criticism, however, this har- vest, it is imperative closer examination of the concept, forecast, guarantee and effective- ness fundamental human rights, which may lead to a mixed application of universalistic and relativistic theories when analyzed from the perspective of these institutes. The Hu- man Right to Development (RtD presupposes notions of environmental sustainability and economic democracy, with qualified participation of social subjects (wide citizenship, seen continuous and articulated perspective as guiding the development process.

  3. Solidarity and the Universal Declaration on Bioethics and Human Rights.

    Science.gov (United States)

    Gunson, Darryl

    2009-06-01

    Recent work has stressed the importance of the concept of solidarity to bioethics and social philosophy generally. But can and should it feature in documents such as the Universal Declaration on Bioethics and Human Rights as anything more than a vague notion with multiple possible interpretations? Although noting the tension between universality and particularity that such documents have to deal with, and also noting that solidarity has a political content, the paper explores the suggestion that solidarity should feature more centrally in international regulations. The paper concludes with the view that when solidarity is seen aright, the UDBHR is an implicitly solidaristic document.

  4. The relationship of the factor V Leiden mutation or the deletion-deletion polymorphism of the angiotensin converting enzyme to postoperative thromboembolic events following total joint arthroplasty

    Directory of Open Access Journals (Sweden)

    Fang Carrie

    2001-04-01

    Full Text Available Abstract Background Although all patients undergoing total joint arthroplasty are subjected to similar risk factors that predispose to thromboembolism, only a subset of patients develop this complication. The objective of this study was to determine whether a specific genetic profile is associated with a higher risk of developing a postoperative thromboembolic complication. Specifically, we examined if the Factor V Leiden (FVL mutation or the deletion polymorphism of the angiotensin-converting enzyme (ACE gene increased a patient's risk for postoperative thromboembolic events. The FVL mutation has been associated with an increased risk of idiopathic thromboembolism and the deletion polymorphism of the ACE gene has been associated with increased vascular tone, attenuated fibrinolysis and increased platelet aggregation. Methods The presence of these genetic profiles was determined for 38 patients who had a postoperative symptomatic pulmonary embolus or proximal deep venous thrombosis and 241 control patients without thrombosis using molecular biological techniques. Results The Factor V Leiden mutation was present in none of the 38 experimental patients and in 3% or 8 of the 241 controls (p = 0.26. Similarly there was no difference detected in the distribution of polymorphisms for the ACE gene with the deletion-deletion genotype present in 36% or 13 of the 38 experimental patients and in 31% or 74 of the 241 controls (p = 0.32. Conclusions Our results suggest that neither of these potentially hypercoaguable states are associated with an increased risk of symptomatic thromboembolic events following total hip or knee arthroplasty in patients receiving pharmacological thromboprophylaxis.

  5. Zambezia: The Journal of Humanities of the University of Zimbabwe ...

    African Journals Online (AJOL)

    Zambezia: The Journal of Humanities of the University of Zimbabwe: Advanced Search ... Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., archive ((journal OR conference) NOT theses); Search for an exact phrase by ...

  6. Ehrenfest en Einstein. Menselijke katalysator van het heldere denken

    Directory of Open Access Journals (Sweden)

    Marijn J. Hollestelle

    2016-10-01

    Full Text Available Ehrenfest and EinsteinEhrenfest and Einstein met just before Ehrenfest became professor at Leiden University. They had much in common and became best friends. Ehrenfest shed light on some problematic aspects of Einstein’s work and during the years acted as an important sparring partner for Einstein. Ehrenfest also explained difficult aspects of Einstein’s work to the physics community. He set others on the track of working on general relativity and made Leiden an international centre for these developments during the years 1912–1920. Ehrenfest made sure Einstein was appointed part-time professor at Leiden, from which Leiden physics profited. He also aided Bohr and Einstein during their notorious debates. Ehrenfest struggled with depression his whole life. The rapid developments and mathematicising of quantum physics, Hitler’s appointment as Reichs Chancellor, money and marriage problems worsened his depressions. In 1933 Ehrenfest committed suicide, and Einstein moved to the United States and away from the study on quantum physics.

  7. Zambezia: The Journal of Humanities of the University of Zimbabwe

    African Journals Online (AJOL)

    Zambezia is a bi-annual journal of the University of Zimbabwe. Its focus is humanities in Zimbabwe and the surrounding region but specialist articles of a more general interest are also published. Vol 32, No 1 (2005). DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT Subscription or Fee Access. Table of ...

  8. Teaching Humanities in Medicine: The University of Massachusetts Family Medicine Residency Program Experience

    Science.gov (United States)

    Silk, Hugh; Shields, Sara

    2012-01-01

    Humanities in medicine (HIM) is an important aspect of medical education intended to help preserve humanism and a focus on patients. At the University of Massachusetts Family Medicine Residency Program, we have been expanding our HIM curriculum for our residents including orientation, home visit reflective writing, didactics and a department-wide…

  9. University Students' Knowledge and Attitudes Regarding Cervical Cancer, Human Papillomavirus, and Human Papillomavirus Vaccines in Turkey

    Science.gov (United States)

    Koç, Zeliha

    2015-01-01

    Objectives: The current descriptive study aimed to determine university students' knowledge and attitudes regarding cervical cancer, human papillomavirus (HPV), and HPV vaccines in Turkey. Participants: A total of 800 students participated. Methods: This study was carried out between September 1, 2012, and October 30, 2012, in 8 female…

  10. van der Waals

    Indian Academy of Sciences (India)

    University education was beyond reach for van der Waals as he had to work for earning his daily bread ... languages, which was a prerequisite for entering a University those days. van der Waals worked as a school ... take academic examinations at the University yet, van der Waals continued studying at Leiden. University ...

  11. Do Colleges and Universities Increase Their Region's Human Capital? Staff Report No. 401

    Science.gov (United States)

    Abel, Jaison R.; Deitz, Richard

    2009-01-01

    We investigate whether the degree production and research and development (R&D) activities of colleges and universities are related to the amount and types of human capital present in the metropolitan areas where the institutions are located. We find that degree production has only a small positive relationship with local stocks of human capital,…

  12. Human Rights and the Political Economy of Universal Health Care: Designing Equitable Financing.

    Science.gov (United States)

    Rudiger, Anja

    2016-12-01

    Health system financing is a critical factor in securing universal health care and achieving equity in access and payment. The human rights framework offers valuable guidance for designing a financing strategy that meets these goals. This article presents a rights-based approach to health care financing developed by the human right to health care movement in the United States. Grounded in a human rights analysis of private, market-based health insurance, advocates make the case for public financing through progressive taxation. Financing mechanisms are measured against the twin goals of guaranteeing access to care and advancing economic equity. The added focus on the redistributive potential of health care financing recasts health reform as an economic policy intervention that can help fulfill broader economic and social rights obligations. Based on a review of recent universal health care reform efforts in the state of Vermont, this article reports on a rights-based public financing plan and model, which includes a new business tax directed against wage disparities. The modeling results suggest that a health system financed through equitable taxation could produce significant redistributive effects, thus increasing economic equity while generating sufficient funds to provide comprehensive health care as a universal public good.

  13. Environmental performances of gas pipe materials

    International Nuclear Information System (INIS)

    Van Nifterik, G.

    1996-01-01

    In constructing new gas pipelines energy distribution companies are increasingly dealing with the question of which material has the lowest environmental impact. Gastec (Dutch gas research institute) and the 'Centrum voor Milieukunde Leiden' (Centre for Environmental Studies of the University of Leiden) studied and compared the environmental aspects of such materials. The study concerns the entire life cycle from raw materials production through digging and welding or fusion joining to the moment the materials are discarded as waste. 2 figs

  14. The Significance of UNESCO’s Universal Declaration on the Human Genome & Human Rights

    Directory of Open Access Journals (Sweden)

    Shawn H.E. Harmon

    2005-03-01

    Full Text Available Modern medical research, particularly genetic research, is changing the nature of medicine. Concerns surrounding these changes and their potential negative impact on human rights led UNESCO to spearhead collaboration by experts in the creation of an international instrument intended to provide guidance for the promotion of bioethics and the protection of human rights in the genetic context. The result was the Universal Declaration of the Human Genome and Human Rights. This article briefly highlights the scientific and social setting into which the Declaration was injected. This is followed by a consideration of the drafting body (the IBC so as to assess whether UNESCO was the appropriate body to lead this project. The process by which the Declaration was created is also considered so as to assess whether it represents an example of ethical and democratic drafting. Finally, the substantive content of the Declaration is considered and measured against the pre-existing regime so as to assess whether it represents an intelligible and coherent response to the concerns raised capable of offering guidance now and into the future. By assessing these procedural and substantive matters, one can draw some tentative conclusions about the utility and significance of the Declaration.

  15. Pain Assessment in Impaired Cognition (PAIC: content validity of the Dutch version of a new and universal tool to measure pain in dementia

    Directory of Open Access Journals (Sweden)

    van Dalen-Kok AH

    2017-12-01

    Full Text Available Annelore H van Dalen-Kok,1 Wilco P Achterberg,1 Wieke E Rijkmans,1 Sara A Tukker-van Vuuren,1 Suzanne Delwel,2,3 Henrica CW de Vet,4 Frank Lobbezoo,2,5 Margot WM de Waal1 1Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, 2Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA, University of Amsterdam and VU University Amsterdam, 3Department of Clinical Neuropsychology, Faculty of Behavioral and Movement Sciences, VU University, 4Department of Epidemiology and Biostatistics, The EMGO Institute for Health and Care Research, VU University Medical Center, 5MOVE Research Institute Amsterdam, VU University, Amsterdam, the Netherlands Objectives: Detection and measurement of pain in persons with dementia by using observational pain measurement tools is essential. However, the evidence for the psychometric properties of existing observational tools remains limited. Therefore, a new meta-tool has been developed: Pain Assessment in Impaired Cognition (PAIC, as a collaborative EU action. The aim is to describe the translation procedure and content validity of the Dutch version of the PAIC.Methods: Translation of the PAIC into Dutch followed the forward-backward approach of the Guidelines for Establishing Cultural Equivalence of Instruments. A questionnaire survey was administered to clinical nursing home experts (20 physicians and 20 nurses to determine whether the PAIC items are indicative of pain and whether items are specific for pain or for other disorders (anxiety disorder, delirium, dementia, or depression. To quantify content validity, mean scores per item were calculated.Results: Eleven items were indicative of pain, for example, “frowning,” “freezing,” and “groaning.” Fifteen items were considered to be pain-specific, for example, “frowning,” “curling up,” and “complaining.” There were discrepancies between the notion of pain characteristics according to nurses

  16. [A clinical case of young, oral combined contraceptive using women, heterozygous carrier of the Factor V (Leiden) which revealed thrombosis of the left internal jugular vein and brain ischemia with cerebral infarction and ischemic stroke].

    Science.gov (United States)

    Kovachev, S; Ramshev, K; Ramsheva, Z; Ivanov, A; Ganovska, A

    2013-01-01

    Thrombophilia is associated with increased risks of venous thrombosis in women taking oral contraceptive preparations. Universal thrombophilia screening in women prior to prescribing oral contraceptive preparations is not supported by current evidence. The case is presented of a 23 year-old women with a personal history of interruption and on the same day started with oral contraceptive (0.03 microg ethynil estradiol - 0.075 microg gestodene), which due on a 18 pill/day to acute headache, increasing vomiting and speaking defects. Physical/neurologic/gynecologic examinations observed a normal status. The MRI and CT revealed thrombosis of the left internal jugular vein and brain ischemia with cerebral infarction and ischemic stroke. The acute therapy of thrombotic findings was accompanied with many tests. The thrombophilia PCR-Real time - test finds heterozygous carrier of the Factor V (Leiden). This case shows the need of large prospective studies that should be undertaken to refine the risks and establish the associations of thrombophilias with venous thrombosis among contraceptive users. The key to a prompt diagnosis is to know the risk factors. The relative value of a thrombophilia screening programme before contraceptive using needs to be established.

  17. Intravenous Remifentanil Analgaesia for an Obstetric Patient with Type I Neurofibromatosis and a Factor V Leiden Mutation

    Directory of Open Access Journals (Sweden)

    José L. Gálvez

    2018-01-01

    Full Text Available Type I neurofibromatosis is characterised by altered skin pigmentation and the growth of benign tumours, particularly along the peripheral nerves and central nervous system. We report a 36-year-old primigravida woman in labour who was admitted to the obstetric suite of the Hospital Sant Joan de Déu, Barcelona, Spain, in 2007 with hypothyroidism, type I neurofibromatosis and a factor V Leiden mutation. Due to a lack of cranial and spinal imaging data, an epidural was not indicated; instead, continuous intravenous remifentanil analgaesia was administered. The remifentanil infusion was self-titrated by the patient using a visual analogue scale, with the dosage ranging from 0.01 to 0.25 μg/kg/minute. Due to rotational dystocia, Kjelland-type forceps were used during the delivery. After birth, the infant was found to have Apgar scores of 9 and 10, with no maternal or neonatal adverse effects observed. Although still controversial, remifentanil may be a successful alternative for analgaesia in similar cases; however, the specific risks and benefits for each patient should be considered prior to administration.

  18. Prednisone Therapy for Duchenne Dystrophy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-02-01

    Full Text Available The effects of prednisone on muscle function and the extent of steroid-related adverse effects were studied in 17 ambulant children with Duchenne muscular dystrophy (DMD at University Hospital, Groningen; Rehabilitation Centre, Utrecht; and Leiden University Medical Centre, the Netherlands.

  19. Factor V Leiden does not have a role in cryptogenic ischemic stroke among Iranian young adults.

    Science.gov (United States)

    Kheradmand, Ehsan; Pourhossein, Meraj; Amini, Gilda; Saadatnia, Mohammad

    2014-01-01

    Different risk factors have been suggested for ischemic stroke in young adults. In a group of these patients despite of extensive diagnostic work-up, the primary cause remains unknown. Coagulation tendency is accounted as a possible cause in these patients. Previous studies on factor V Leiden (FVL) as the main cause of inherited thrombophilia for clarifying the role of FVL in stroke have resulted in controversial findings. The current study investigates the role of this factor in ischemic stroke among Iranians. This case-control study was performed between September 2007 and December 2008 in Isfahan, Iran. The case group comprised of 22 patients of which 15 were males and 7 were females with age range of ≤50 years, diagnosed as ischemic stroke without classic risk factors and the control group consisted of 54 healthy young adults. After filling consent form, venous blood samples were obtained and sent to the laboratory for genetic examination. No FVL mutation was found in the case group. There was one carrier of the mutation as heterozygous in the control group (relative frequency = 1.85%). Based on our study, FVL might not be considered as an independent risk factor for ischemic stroke in Iranian individuals who are not suffering from other risk factors of ischemic stroke.

  20. Factor V leiden and ischemic stroke risk: the Genetics of Early Onset Stroke (GEOS) study.

    Science.gov (United States)

    Hamedani, Ali G; Cole, John W; Cheng, Yuching; Sparks, Mary J; O'Connell, Jeffrey R; Stine, Oscar C; Wozniak, Marcella A; Stern, Barney J; Mitchell, Braxton D; Kittner, Steven J

    2013-05-01

    Factor V Leiden (FVL) has been associated with ischemic stroke in children but not in adults. Although the FVL mutation is associated with increased risk for venous thrombosis, its association with ischemic stroke in young adults remains uncertain. Therefore, we examined the association between FVL and ischemic stroke in participants of the Genetics of Early Onset Stroke (GEOS) study. A population-based case control study identified 354 women and 476 men 15 to 49 years of age with first-ever ischemic stroke and 907 controls. Participant-specific data included vascular risk factors, FVL genotype and, for cases, the ischemic stroke subtype by modified Trial of ORG 10172 in Acute Stroke criteria. Logistic regression was used to calculate odds ratios for the entire population and for subgroups stratified by risk factors and ischemic stroke subtype. The frequency of the FVL mutation was similar between ischemic stroke patients (3.6%; 95% confidence interval [CI] 2.5%-5.1%) and nonstroke controls (3.8%; 95% CI 2.7%-5.2%). This frequency did not change significantly when cases were restricted to patients with stroke of undetermined etiology (4.1%; 95% CI 2.6%-6.4%). Among young adults, we found no evidence for an association between FVL and either all ischemic stroke or the subgroup with stroke of undetermined etiology. Published by Elsevier Inc.

  1. The politics of universalism. Strategic uses of human rights discourses in early modernity

    Directory of Open Access Journals (Sweden)

    Karen-Margrethe Simonsen

    2013-11-01

    Full Text Available This article investigates the political function of human rights in 16th-century Spain just after the conquest of America. It claims that the study of this period of early globalization is relevant for an understanding of the function of human rights discourses today, at the “end” of globalization. Historically speaking, human rights are closely connected with globalization, but at the same time, they raise the question about the foundation of globalization: is there a universal community or only economic and political power-relations? This article argues that the political use of human rights discourses is split down the middle: it serves both as a critique of power and as an extension of power, and the disclosure of this split helps us understand the inner politics of human rights. The article discusses the trial in Valladolid in 1550 when the rights of the barbarian Indians of America were put on trial. It focuses mainly on the arguments made by Bartolomé de las Casas and on the reasons why the King allowed las Casas’ fierce critique of the conquest to be published in a period of otherwise severe censorship. This article is inspired by Etienne Balibar's idea of “politics of universalism,” “political autonomy,” and “equaliberty.”.

  2. Universities and a Human Development Ethics: A Capabilities Approach to Curriculum

    Science.gov (United States)

    Walker, Melanie

    2012-01-01

    This article takes up the challenge of curriculum change in relation to the contested purposes of universities. It argues for an expansive, public good understanding, rather than the thin market exchange norms which currently drive higher education policies. The paper suggests that a human capital approach to curriculum is then insufficient to…

  3. Coagulopathy triggered autoimmunity: experimental antiphospholipid syndrome in factor V Leiden mice

    Science.gov (United States)

    2013-01-01

    Background We investigated interactions between genetically and autoimmune-mediated coagulopathies by inducing experimental antiphospholipid syndrome (eAPS) in mice carrying the factor V Leiden (FVL) mutation. Methods eAPS was induced in heterozygous and homozygous FVL transgenic mice (C57BL/6 background) by immunization with β2-glycoprotein I (β2-GPI). Autoantibody levels were measured at 1 and 5 months post-immunization. Mice were tested at 4 months post-immunization for behavior and cognitive function in the staircase, elevated plus-maze, and swim T-maze tests. Brains were removed and analyzed by immunohistochemistry for inflammatory markers and neurodegenerative processes. Results A single immunization with β2-GPI induced significantly higher and longer-lasting immune responses, and this was dependent on the number of FVL alleles. At 1 and 5 months post-immunization, levels of antibodies rose from 1.17 ± 0.07 to 1.62 ± 0.17 (optical density units; ODU) in homozygous FVL mice, compared with stable levels of 0.59 ± 0.17 and 0.48 ± 0.16 ODU in heterozygous FVL mice and a drop from 1.62 ± 0.21 to 0.61 ± 0.13 ODU in wild-type mice. Behavioral and cognitive clinical features of eAPS were also correlated with FVL allele load, as assessed by the elevated plus-maze (altered anxiety), staircase (hyperactivity and higher exploration), and swim T-maze (impaired learning) tests. Histological studies identified significant neurodegenerative changes in both grey and white matter in the eAPS-FVL brains. In spite of the potential interaction of two prothrombotic disease states, there were no ischemic lesions seen in this group. Conclusions The results indicate that genetically mediated coagulopathies increase the risk of developing coagulation-targeted autoimmune responses, and suggest the importance of antibody-mediated neurodegenerative processes in the brain in APS. PMID:23566870

  4. University-Firm Interactions in Brazil: Beyond Human Resources and Training Missions

    Science.gov (United States)

    Rapini, Marcia Siqueira; Chiarini, Tulio; Bittencourt, Pablo Felipe

    2015-01-01

    The motivation for this article comes from the proposition in the literature that Latin American universities are detached from the research needs of the productive sector and that they limit their role to the human resources and training missions. The authors investigated the Brazilian scenario, using data from a survey conducted in 2008-2009…

  5. The Universal Declaration of Human Rights: 50 Years Old but Still Coming of Age.

    Science.gov (United States)

    Flowers, Nancy

    1998-01-01

    Highlights the events of the past 50 years concerning the Universal Declaration of Human Rights that is the first document in human history to codify rights that apply to every person regardless of citizenship in a particular country. Explains why the United States does not comprehend the value of the declaration. (CMK)

  6. Who's afraid of Patterns?: The Particular versus the Universal and the Meaning of Humanities 3.0

    Directory of Open Access Journals (Sweden)

    Rens Bod

    2013-12-01

    Full Text Available The advent of Digital Humanities has enabled scholars to identify previously unknown patterns in the arts and letters; but the notion of pattern has also been subject to debate. In my response to the authors of this Forum, I argue that ‘pattern’ should not be confused with universal pattern. The term pattern itself is neutral with respect to being either particular or universal. Yet the testing and discovery of patterns – be they local or global – is greatly aided by digital tools. While such tools have been beneficial for the humanities, numerous scholars lack a sufficient grasp of the underlying assumptions and methods of these tools. I argue that in order to criticise and interpret the results of digital humanities properly, scholars must acquire a good working knowledge of the underlying tools and methods. Only then can digital humanities be fully integrated (humanities 3.0 with time-honoured (humanities 1.0 tools of hermeneutics and criticism.

  7. Getting Pole Position: Research Strategies in the Humanities at Swedish Universities

    Science.gov (United States)

    Geschwind, Lars

    2010-01-01

    The aim of this paper is to study research strategies in the Humanities in Sweden. The Swedish higher education sector is under transformation and a new funding system has been proposed. The study investigates the university strategy processes, mainly at the dean's level. The results show that most institutions are active in order to be well…

  8. The quantum theory of time, the block universe, and human experience.

    Science.gov (United States)

    Vaccaro, Joan A

    2018-07-13

    Advances in our understanding of the physical universe have dramatically affected how we view ourselves. Right at the core of all modern thinking about the universe is the assumption that dynamics is an elemental feature that exists without question. However, ongoing research into the quantum nature of time is challenging this view: my recently introduced quantum theory of time suggests that dynamics may be a phenomenological consequence of a fundamental violation of time reversal symmetry. I show here that there is consistency between the new theory and the block universe view. I also discuss the new theory in relation to the human experience of existing in the present moment, able to reflect on the past and contemplate a future that is yet to happen.This article is part of a discussion meeting issue 'Foundations of quantum mechanics and their impact on contemporary society'. © 2018 The Authors.

  9. Experiments on chemical and physical evolution of interstellar grain mantles

    International Nuclear Information System (INIS)

    Greenberg, J.M.

    1984-01-01

    The Astrophysical Laboratory at the University of Leiden is the first to succeed in simulating the essential conditions in interstellar space as they affect the evolution of interstellar grains. (author)

  10. A prepared speech in front of a pre-recorded audience: subjective, physiological, and neuroendocrine responses to the Leiden Public Speaking Task.

    Science.gov (United States)

    Westenberg, P Michiel; Bokhorst, Caroline L; Miers, Anne C; Sumter, Sindy R; Kallen, Victor L; van Pelt, Johannes; Blöte, Anke W

    2009-10-01

    This study describes a new public speaking protocol for youth. The main question asked whether a speech prepared at home and given in front of a pre-recorded audience creates a condition of social-evaluative threat. Findings showed that, on average, this task elicits a moderate stress response in a community sample of 83 12- to 15-year-old adolescents. During the speech, participants reported feeling more nervous and having higher heart rate and sweatiness of the hands than at baseline or recovery. Likewise, physiological (heart rate and skin conductance) and neuroendocrine (cortisol) activity were higher during the speech than at baseline or recovery. Additionally, an anticipation effect was observed: baseline levels were higher than recovery levels for most variables. Taking the anticipation and speech response together, a substantial cortisol response was observed for 55% of participants. The findings indicate that the Leiden Public Speaking Task might be particularly suited to investigate individual differences in sensitivity to social-evaluative situations.

  11. STUDENTS’ EVALUATION OF EDUCATION QUALITY IN HUMAN RESOURCE MANAGEMENT AREA: CASE OF PRIVATE CZECH UNIVERSITY

    Directory of Open Access Journals (Sweden)

    VNOUČKOVÁ, Lucie

    2016-06-01

    Full Text Available The quality of education, lessons, subjects and teachers perceived by students is currently often discussed topic regarding strategic management of universities. Assessment of higher education learning outcomes represents internalization of a higher education competition. The aim of the article is to evaluate perception of education quality of lectures, subjects and teachers by university students in the area of human resource management in private Czech university and to identify main approaches to academic staff. The data were collected by quantitative survey by questionnaire data collection (n=218. Students state that subjects, lessons and teachers in the area of human resource management lessons mostly satisfied their expectations (average value between 1.09 and 1.97. The students emphasised that the staff creates positive atmosphere and gives the opportunity to express an opinion which is very important for students at the university. Research outcomes show there is a dependency between the effort of teacher, student understanding and teachers’s willingness to give students an opportunity to express an opinion. The paper is extension of conference paper presented on ERIE conference 2016.

  12. [Towards an universal biolaw? Biolaw in action and funcionalization of human life's value].

    Science.gov (United States)

    Albert, Marta

    2013-01-01

    The paper analyzes the question of the universal biolaw from the point of view of the biojuridical praxis. The main problems concerning life's protection are found in the process of interpretation and re-creation of the norms (not in their literal texts) regulating the right to life and new rights, as personal autonomy. But it is also at this sphere where the possibilities of an universal biolaw founded on the funcionalization of the human life value are to be found.

  13. Human Space Exploration and Human Space Flight: Latency and the Cognitive Scale of the Universe

    Science.gov (United States)

    Lester, Dan; Thronson, Harley

    2011-01-01

    The role of telerobotics in space exploration as placing human cognition on other worlds is limited almost entirely by the speed of light, and the consequent communications latency that results from large distances. This latency is the time delay between the human brain at one end, and the telerobotic effector and sensor at the other end. While telerobotics and virtual presence is a technology that is rapidly becoming more sophisticated, with strong commercial interest on the Earth, this time delay, along with the neurological timescale of a human being, quantitatively defines the cognitive horizon for any locale in space. That is, how distant can an operator be from a robot and not be significantly impacted by latency? We explore that cognitive timescale of the universe, and consider the implications for telerobotics, human space flight, and participation by larger numbers of people in space exploration. We conclude that, with advanced telepresence, sophisticated robots could be operated with high cognition throughout a lunar hemisphere by astronauts within a station at an Earth-Moon Ll or L2 venue. Likewise, complex telerobotic servicing of satellites in geosynchronous orbit can be carried out from suitable terrestrial stations.

  14. A Tale of Many Cities: Universal Patterns in Human Urban Mobility

    Science.gov (United States)

    Noulas, Anastasios; Scellato, Salvatore; Lambiotte, Renaud; Pontil, Massimiliano; Mascolo, Cecilia

    2012-01-01

    The advent of geographic online social networks such as Foursquare, where users voluntarily signal their current location, opens the door to powerful studies on human movement. In particular the fine granularity of the location data, with GPS accuracy down to 10 meters, and the worldwide scale of Foursquare adoption are unprecedented. In this paper we study urban mobility patterns of people in several metropolitan cities around the globe by analyzing a large set of Foursquare users. Surprisingly, while there are variations in human movement in different cities, our analysis shows that those are predominantly due to different distributions of places across different urban environments. Moreover, a universal law for human mobility is identified, which isolates as a key component the rank-distance, factoring in the number of places between origin and destination, rather than pure physical distance, as considered in some previous works. Building on our findings, we also show how a rank-based movement model accurately captures real human movements in different cities. PMID:22666339

  15. A tale of many cities: universal patterns in human urban mobility.

    Directory of Open Access Journals (Sweden)

    Anastasios Noulas

    Full Text Available The advent of geographic online social networks such as Foursquare, where users voluntarily signal their current location, opens the door to powerful studies on human movement. In particular the fine granularity of the location data, with GPS accuracy down to 10 meters, and the worldwide scale of Foursquare adoption are unprecedented. In this paper we study urban mobility patterns of people in several metropolitan cities around the globe by analyzing a large set of Foursquare users. Surprisingly, while there are variations in human movement in different cities, our analysis shows that those are predominantly due to different distributions of places across different urban environments. Moreover, a universal law for human mobility is identified, which isolates as a key component the rank-distance, factoring in the number of places between origin and destination, rather than pure physical distance, as considered in some previous works. Building on our findings, we also show how a rank-based movement model accurately captures real human movements in different cities.

  16. Frederik Kaiser (1808-1872, een gekweld man met een missie

    Directory of Open Access Journals (Sweden)

    Huib Zuidervaart

    2011-06-01

    Full Text Available Frederik Kaiser (1808-1872, a tormented man with a missionThe Leiden astronomer Kaiser has been instrumental for the rise of Dutch astronomy in the late nineteenth-century. His career was impressive. In 1826, without any formal university education, he began at the Leiden Astronomical Observatory as an ordinary observer. Through his work in astronomy he obtained an honorary doctorate, which enabled him in 1838 to become director of the observatory. In 1844 he was appointed full professor and in the academic year 1857/1858 he even became Rector Magnificus of Leiden University. In 1860 he even saw the fulfillmentof his life-long dream: the opening of a brand new astronomical observatory. However, in spite of these obvious professional successes, Kaiser's personal life was full of melancholy. This paper investigates Kaiser's personality, using correspondence with his family, as well as testimonies written down by his students and other contemporaries. Among others, we demonstrate the way in which Kaiser used his personal network, as well as his fierce continuous – and often publicly expressed – complaining, as a successful strategy in establishing his new astronomical observatory.

  17. Unravelling 21st Century Riddles – Universal Network Visions from a Human Perspective

    NARCIS (Netherlands)

    Baken, N.; Van Belleghem, N.; Van Boven, E.; De Korte, A.

    2006-01-01

    Networks are omnipresent and universal. Mankind, for example, forms a social network. Today, information and communications technology (ICT) exponentially accelerates the interaction between the human nodes of this global social network. In that way, ICT appears to evoke a phase transformation,

  18. Identity and the Hegemony of Universal Human Rights

    Directory of Open Access Journals (Sweden)

    Tony Evans

    2017-01-01

    Full Text Available Human rights are commonly portrayed as a narrative that passes through several chapters before reaching its inevitable conclusion. This narrative begins with the horror of Nazism, moves to the centrality of human rights in the UN Charter, eulogizes the Universal Declaration, celebrates the achievements of standard setting as set out in the major covenants, offers detailed analysis of methods of monitoring and, finally, speculates on the future of compliance. This narrative is sustained, firstly, by ‘naturalist’ foundationalism and, secondly, by a widely held assumptions about the move towards ‘settled norms’ in the contemporary world order. Although some pessimism is voiced over continued reports of torture, genocide, structural economic deprivation, disappearances, ethnic cleansing, political prisoners, the suppression of trade union rights, gender inequality, religious persecution, and many other violations of internationally agreed human rights, most commentators and activists tacitly adopt an optimistic stance that envisages a future rights based international order. The still prevalent naturalist account of human rights, together with a narrative that boasts ‘settled norms’, suggests that the human rights regime represents a final ‘truth’ about the essential nature of all humankind; a common identity that describes the individual in an increasingly globalized world. This paper interrogates the ‘naturalist-settled norm’ account of human rights from the perspective of power and knowledge. It begins by distinguishing between the international human rights regime and the global discourse of human rights. The former adopts a legal approach, where the neutral, value-free, unbiased and impartial nature of the law is tacitly accepted. The latter refers to human rights as social, political and economic practice, and must therefore include an account of power. From this perspective, the discourse of human rights might be said to

  19. Deep vein thrombosis, ecythyma gangrenosum and heparin-induced thrombocytopenia occurring in a man with a heterozygous Factor V Leiden mutation

    Directory of Open Access Journals (Sweden)

    Mariya Apostolova

    2012-11-01

    Full Text Available Skin necrosis and limb gangrene are occasional thrombotic manifestations of anticoagulation therapy. We report a man heterozygous for the Factor V Leiden (FVL mutation, and with a history of recurrent deep venous thrombosis, who initially presented with a necrotic skin lesion of the right flank while on warfarin therapy with a therapeutic international normalized ratio. Warfarin was discontinued and he received intravenous heparin. Thereafter he developed thrombocytopenia and pedal erythema and was diagnosed with heparin-induced thrombocytopenia (HIT. Heparin was replaced with argatroban. He ultimately underwent bilateral below-knee amputations for the thrombotic complications of the HIT. The initial necrotic lesion healed with antibiotics and wound care. Pathologic examination of multiple biopsy specimens revealed two separate lesions. One was necrotic tissue infiltrated with methicillin resistant Staphylococcus aureus having features of ecthyma gangrenosum. The second showed thrombotic changes consistent with HIT. The case illustrates the differential diagnosis of skin necrosis and limb gangrene in patients on warfarin and heparin, and also the clinical complexities that can occur in a FVL heterozygote.

  20. LGBT rights versus Asian values: de/re-constructing the universality of human rights

    OpenAIRE

    Lee, Po-Han

    2016-01-01

    Law, especially from the international human rights regime, is a direct reference on which minority groups rely when it comes to ‘non-discrimination’. Drawing upon LGBT rights in Taiwan, as well as Hong Kong and Singapore, this article – through an application of K.H. Chen’s (2010) Asia as Method – critically reviews how global LGBT politics interact with local societies influenced by Confucianism. Along a perpetual competition between the universalism and cultural relativism of human rights,...

  1. Chlamydia trachomatis and genital human papillomavirus infections in female university students in Honduras.

    NARCIS (Netherlands)

    Tabora, N.; Zelaya, A.; Bakkers, J.; Melchers, W.J.; Ferrera, A.

    2005-01-01

    Sexually transmitted infections are a serious health problem in Honduras. Human papillomavirus (HPV) and Chlamydia trachomatis are major causes of sexually transmitted diseases. To determine the prevalence of C. trachomatis and HPV in young women, 100 female university students in Honduras were

  2. Is this a FAIR data repository?

    OpenAIRE

    Boehmer, Jasmin

    2017-01-01

    Presentation given as part of coaching task for University Leiden LIACS TEAM TASKS INFORMATICS ORIENTATION, on 17th November 2017. Group 3 - FAIR data with Rolf Kleef from International Aid Transparency Initiative (IATI).

  3. Why was this transfusion given? Identifying clinical indications for blood transfusion in health care data

    Directory of Open Access Journals (Sweden)

    van Hoeven LR

    2018-03-01

    Full Text Available Loan R van Hoeven,1,2 Aukje L Kreuger,3,4 Kit CB Roes,1 Peter F Kemper,2,4 Hendrik Koffijberg,5 Floris J Kranenburg,3,4,6 Jan MM Rondeel,7 Mart P Janssen1,2 1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 2Transfusion Technology Assessment Department, Sanquin Research, Amsterdam, the Netherlands; 3Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; 4Center for Clinical Transfusion Research, Sanquin Research, Leiden, the Netherlands; 5Department of Health Technology & Services Research, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, the Netherlands; 6Department of Intensive Care, Leiden University Medical Center, Leiden, the Netherlands; 7Department of Clinical Chemistry, Isala, Zwolle, the Netherlands Background: To enhance the utility of transfusion data for research, ideally every transfusion should be linked to a primary clinical indication. In electronic patient records, many diagnostic and procedural codes are registered, but unfortunately, it is usually not specified which one is the reason for transfusion. Therefore, a method is needed to determine the most likely indication for transfusion in an automated way.Study design and methods: An algorithm to identify the most likely transfusion indication was developed and evaluated against a gold standard based on the review of medical records for 234 cases by 2 experts. In a second step, information on misclassification was used to fine-tune the initial algorithm. The adapted algorithm predicts, out of all data available, the most likely indication for transfusion using information on medical specialism, surgical procedures, and diagnosis and procedure dates relative to the transfusion date.Results: The adapted algorithm was able to predict 74.4% of indications in the sample correctly (extrapolated to the full data set 75.5%. A kappa

  4. Deepest Infrared View of the Universe

    Science.gov (United States)

    2002-12-01

    VLT Images Progenitors of Today's Large Galaxies Summary An international team of astronomers [2] has made the deepest-ever near-infrared Ks-band image of the sky, using the ISAAC multi-mode instrument on the 8.2-m VLT ANTU telescope. For this, the VLT was pointed for more than 100 hours under optimal observing conditions at the Hubble Deep Field South (HDF-S) and obtained images in three near-infrared filters. The resulting images reveal extremely distant galaxies, which appear at infrared wavelengths, but are barely detected in the deepest optical images acquired with the Hubble Space Telescope (HST). Astronomer Marijn Franx from the University of Leiden and leader of the team concludes: "These results demonstrate that very deep observations in the near-infrared are essential to obtain a proper census of the earliest phases of the universe. The new VLT images have opened a new research domain which has not been observationally accessible before". The HDF-S is a tiny field on the sky in the southern constellation Tucana (The Toucan) - only about 1% of the area of the full moon. The NASA/ESA Hubble Space Telescope (HST) observed it with a total exposure time of about 1 week, yielding the deepest optical images ever taken of the sky, similar to those made earlier on the Hubble Deep Field North (HDF-N). The VLT infrared images of the same field were obtained in the course of a major research project, the Faint InfraRed Extragalactic Survey (FIRES). They were made at wavelengths up to 2.3 µm where the HST is not competitive. Ivo Labbé, another team member from the University of Leiden, is certain: "Without the unique capabilities of the VLT and ISAAC we would never have been able to observe these very remote galaxies. In fact, the image in the Ks-band is the deepest which has ever been made at that wavelength". The optical light emitted by the distant galaxies has been redshifted to the near-infrared spectral region [3]. Indeed, some of the galaxies found in the new

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Roxana Waterson

    1993-01-01

    Full Text Available - Donald F. Barr, J. Noorduyn, A critical survey of studies on the languages of Sulawesi, Leiden: KITLV Press, (Bibliographical Series 18, 1991, xiv + 245 pp., maps, index. - J. Boneschansker, H. Reenders, Alternatieve zending, Ottho Gerhard Heldring (1804-1876 en de verbreiding van het christendom in Nederlands-Indië, Kampen, 1991. - H.J.M. Claessen, Albert B. Robillard, Social change in the Pacific Islands. London & New York: Kegan Paul International. 1992, 507 pp. Maps, bibl. - Will Derks, J.J. Ras, Variation, transformation and meaning: Studies on Indonesian literatures in honour of A. Teeuw, Leiden: KITLV Press, (VKI 144, 1991, 236 pp., S.O. Robson (eds. - Will Derks, G.L. Koster, In deze tijd maar nauwelijks te vinden; De Maleise roman van hofjuffer Tamboehan, Vertaald uit het Maleis en ingeleid door G.L. Koster en H.M.J. Maier, Leiden: E.J. Brill, 1991, 174 pp., H.M.J. Maier (eds. - Mark Durie, C.D. Grijns, Jakarta Malay: a multi-dimensional approach to spacial variation. 2 vols., Leiden: KITLV Press, ( VKI 149, 1991. - Jan Fontein, Jan J. Boeles, The secret of Borobudur, Bangkok, privately published, 1985, 90 pp. + appendix, 29 pp. - M. Heins, L. Suryadinata, Military ascendancy and political culture: A study of Indonesia’s Golkar. Ohio: Ohio University, Monographs in International Studies, Southeast Asia Series, no.85, 1989, xiii + 223 pp. - V.J.H. Houben, Ismail Hussein, Antara dunia Melayu dengan dunia kebangsaan. Bangi: penerbit Universiti kebangsaan Malaysia 1990, 68 pp. - Victor T. King, Aruna Gopinath, Pahang 1880-1933: A political history (Monograph/Malaysian branch of the royal Asiatic society, 18. - G.J. Knaap, J. van Goor, Generale Missiven van Gouverneurs-Generaal en Raden aan heren XVII der Verenigde Oostindische Compagnie, IX: 1729-1737 (Rijks Geschiedkundige publicatiën, grote serie 205. ‘s- Gravenhage: Instituut voor Nederlandse Geschiedenis, 1988, xii + 895 p. - Otto D. van den Muijzenberg, John S. Furnivall, The

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Mary Somers Heidhues

    1992-07-01

    Full Text Available - Jet Bakels, Robert Layton, The anthropology of art. Cambridge: Cambridge University Press, 1991, 258 pp. - J.M.S. Baljon, Herman Leonard Beck, De Islam in Nederland: Romancing religion? [Inaugurele rede theologische faculteit Tilburg 14.2.1992.] Tilburg: Tilburg University Press 1992. - R.H. Barnes, J.D.M. Platenkamp, North Halmahera: Non-Austronesian Languages, Austronesian cultures?, Lecture presented to the Oosters Genootschap in Nederland at Leiden on 23 May 1989, Leiden: Oosters Genootschap in Nederland, 1990. 33 pp. - Hans Borkent, Directory of Southeast Asianists in the Pacific Northwest. Compiled by: Northwest Regional Consortium for Southeast Asian Studies. Seattle, WA: University of Washington [et al.], 1990. 108 pp. - Roy Ellen, Frans Hüsken, Cognation and social organization in Southeast Asia. Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde 145. Leiden: KITLV Press, 1991, 221 pp. figs. tables, index., Jeremy Kemp (eds. - C. de Jonge, Huub J.W.M. Boelaars, Indonesianisasi. Het omvormingsproces van de katholieke kerk in Indonesië tot de Indonesische katholieke kerk, Kerk en Theologie in Context, 13, Kampen: Kok, 1991, ix + 472 pp. - Nico de Jonge, Gregory Forth, Space and place in eastern Indonesia, University of Kent at Canterbury, Centre of South-east Asian Studies (Occasional Paper no. 16 1991. 85 pp., ills. - J. Kommers, Bernard Juillerat, Oedipe chasseur. Une mythologie du sujet en Nouvelle-Guinée, P.U.F., Le fil rouge, section 1 Psychanalyse. Paris, 1991. - Gerco Kroes, Signe Howell, Society and cosmos, the Chewong of Peninsular Malaysia, University of Chicago Press, 1989, xv + 294 pp. - Daniel S. Lev, S. Pompe, Indonesian Law 1949-1989: A bibliography of foreign-language materials with brief commentaries on the law, Van Vollenhoven Institute for Law and Administration in Non-Western Countries. Nijhoff, 1992. - A. M. Luyendijk-Elshout, H. den Hertog, De militair geneeskundige verzorging

  7. The relation between flexibility of human resources and performance indexes of selected hospitals of Tehran Medical Sciences University

    Directory of Open Access Journals (Sweden)

    Noushin Alibakhshi

    2016-12-01

    Full Text Available Today, flexibility has turned to one of important issues in management theories and policies and most current discussions about flexibility patterns focus on management policies, so that these patterns are one of important aspects of human resources strategic management. This study was performed with the aim of assessing the flexibility rate of human resources and performance indexes of Tehran Medical Sciences University hospitals and determining the possible relation between these variables. The present study is descriptive – analytical which was conducted in cross-sectional form in 2015. The statistical population was selected by stratifies random sampling method as 317 persons from nursing, administrative and financial personnel of 5 hospitals of Tehran Medical Sciences University. Data collecting toll was hospitals performance indexes form and Wright & Snell flexibility questionnaire of human resources. Data analysis was performed using SPSS 18 software and with the aid of descriptive statistical indexes and linear regression analysis. The results showed that personnel ( human resources had high flexibility = 4.16.\tthere was a significant relation between total flexibility and the index of bed circulation so that by one unit increase in bed circulation space, normally, the average of total flexibility decreased 0.64 units ( p-value<0.05. The results showed that human resources of Tehran Medical Sciences University hospitals have high flexibility, so authorities and policy makers are suggested to adopt policies of human resources management for creating flexibility in human resources and improving hospitals performance and amending hospitals status.

  8. Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

    Directory of Open Access Journals (Sweden)

    Qiang Feng

    2014-11-01

    Full Text Available Human induced pluripotent stem cells (iPSCs provide a potentially replenishable source for the production of transfusable platelets. Here, we describe a method to generate megakaryocytes (MKs and functional platelets from iPSCs in a scalable manner under serum/feeder-free conditions. The method also permits the cryopreservation of MK progenitors, enabling a rapid “surge” capacity when large numbers of platelets are needed. Ultrastructural/morphological analyses show no major differences between iPSC platelets and human blood platelets. iPSC platelets form aggregates, lamellipodia, and filopodia after activation and circulate in macrophage-depleted animals and incorporate into developing mouse thrombi in a manner identical to human platelets. By knocking out the β2-microglobulin gene, we have generated platelets that are negative for the major histocompatibility antigens. The scalable generation of HLA-ABC-negative platelets from a renewable cell source represents an important step toward generating universal platelets for transfusion as well as a potential strategy for the management of platelet refractoriness.

  9. Realizing Universal Health Coverage in East Africa: the relevance of human rights.

    Science.gov (United States)

    Yamin, Alicia Ely; Maleche, Allan

    2017-08-03

    Applying a robust human rights framework would change thinking and decision-making in efforts to achieve Universal Health Coverage (UHC), and advance efforts to promote women's, children's, and adolescents' health in East Africa, which is a priority under the Sustainable Development Agenda. Nevertheless, there is a gap between global rhetoric of human rights and ongoing health reform efforts. This debate article seeks to fill part of that gap by setting out principles of human rights-based approaches (HRBAs), and then applying those principles to questions that countries undertaking efforts toward UHC and promoting women's, children's and adolescents' health, will need to face, focusing in particular on ensuring enabling legal and policy frameworks, establishing fair financing; priority-setting processes, and meaningful oversight and accountability mechanisms. In a region where democratic institutions are notoriously weak, we argue that the explicit application of a meaningful human rights framework could enhance equity, participation and accountability, and in turn the democratic legitimacy of health reform initiatives being undertaken in the region.

  10. Teaching the Universal Declaration of Human Rights in a U.S. Government Course.

    Science.gov (United States)

    Rosen, Philip

    1990-01-01

    Discusses the United Nations Universal Declaration of Human Rights as a vehicle for learning democratic and humanistic values. Provides goals for instruction about the Declaration. Compares the Declaration to U.S. Supreme Court cases and congressional acts, and suggests classroom activities using it. Includes an appendix on Supreme Court cases and…

  11. Knowledge and attitude of Iranian University students toward human papilloma virus.

    Science.gov (United States)

    Ghojazadeh, Morteza; Azar, Zahra Fardi; Saleh, Parviz; Naghavi-Behzad, Mohammad; Azar, Nastaran Ghodratnezhad

    2012-01-01

    Increasing prevalence of human papilloma virus (HPV) infection and its association with cervical cancer as a leading cause of death make it necessary to evaluate and improve the public knowledge, especially of university students, about this cause of disease. A cross-sectional study of knowledge and attitude of a total 669 students from Tabriz University of Medical Sciences was therefore performed with a modified validated questionnaire, arranged into 5 parts and containing 55 questions, in July 2011. Questions were directed to study socio-demographic characteristics of the participant, knowledge about HPV disease, transmission route, relationship with cervical cancer, predisposing factors, and participants attitude toward people with HPV infection. All of the participants were Moslem with a mean age 25.6±5.33 years of age. All of the participants had heard of HPV, and acquired their knowledge through university courses (90.6%); the majority of them knew that HPV is a sexually transmitted disease and a potential cause for genital warts but general knowledge about details was not high. Mean knowledge score of residents and post graduate midwifery and nursing students was high as compared to other groups (Plevel (β=0.21, Pknowledge. Moderate level of knowledge about HPV among medical university students makes it necessary to set effective national public health efforts on HPV education and prevention considering he excess of young population in Iran vulnerable to cervical cancer.

  12. Learning about Factor V Leiden Thrombophilia

    Science.gov (United States)

    ... Care Genomic Medicine Working Group New Horizons and Research Patient Management Policy and Ethics Issues Quick Links for Patient Care Education All About the Human Genome Project Fact Sheets Genetic Education Resources for ...

  13. Teaching Humanities at the National University of la Plata, Argentina.

    Science.gov (United States)

    Acuña, Leopoldo E

    2003-10-01

    In this article the author begins by giving a brief history of medical education in Argentina, then provides some background information on the National University of La Plata. He describes two major initiatives at La Plata: a new and pioneering admission policy (implemented in 1993) and a change in the number of hours and years in the curriculum. He then looks back to the introduction in 1976 of La Plata's medical humanities program. Over its 20 year existence, the program has undergone a number of changes in response both to students' interests and financial concerns. The revised humanities curriculum now consists of four elective courses: medicine and literature, anthropology, history of medicine, and "medical kalology" (which focuses on music and dance). Unfortunately, the program, while it has been well received by both students and faculty and has inspired programs at other Argentinean schools, is threatened by Argentina's economic crisis.

  14. A human reliability analysis of the University of New Mexico's AGN- 201M nuclear research reactor

    International Nuclear Information System (INIS)

    Brumburgh, G.P.; Heger, A.S.

    1992-01-01

    During 1990--1991, a probabilistic risk assessment was conducted on the University of New Mexico's AGN-201M nuclear research reactor to address the risk and consequence of a maximum hypothetical release accident. The assessment indicated a potential for consequential human error to precipitate Chis scenario. Subsequently, a human reliability analysis was performed to evaluate the significance of human interaction on the reactor's safety systems. This paper presents the results of that investigation

  15. The Frequency of Factor V Leiden, Prothrombin G20210A and Methylenetetrahydrofolate Reductase C677T Mutations in Migraine Patients

    Directory of Open Access Journals (Sweden)

    Ruhsen Öcal

    2010-12-01

    Full Text Available OBJECTIVE: Migraine is an independent risk factor for ischemic stroke, but its pathophysiology is still unclear. Genetic factors that predispose patients to thrombosis have been studied in patients with migraine to highlight the pathogenesis, but the results remain controversial. In this study, the frequencies of factor V Leiden (FVL, prothrombin (Pt G20210A and methylenetetrahydrofolate reductase (MTHFR C677T mutations were investigated. METHODS: One hundred and sixty patients aged of 15 to 55 years with no history of systemic disease and who had been diagnosed as migraine according to the International Headache Society (IHS diagnostic criteria at Baskent University Hospital Neurology Outpatient Clinics were investigated for FVL, Pt G20210A and MTHFR C677T mutations from their genomic DNA, and the results were compared with those of healthy controls. RESULTS: One hundred and fifty five (96.9% of 160 migraine patients were homozygote normal, 5 (3.1% were heterozygote and none of them were homozygote mutant for FVL. The control group had 9.8% heterozygote individuals but the difference between the percentages was not statistically significant (p> 0.05. There were no homozygote mutant individuals in the Turkish population study in normal subjects like our study. Thirty nine (24.4% of 160 migraine patients were heterozygote and 8 (5% were homozygote mutant for MTHFR C677T. The control group had 37 (34.9% heterozygote and 6 (5.6% homozygote mutant individuals. The difference between the percentages was not statistically significant (p= 0.15. Three (1.9% of 160 migraine patients were heterozygote and 5 (2.9% of the control group were heterozygote mutant for Pt G20210A mutation. The control group had 37 (34.9% heterozygote and 6 (5.6% homozygote mutant individuals. The difference between the percentages was not statistically significant (p= 0.420. CONCLUSION: Our study indicates that FVL, Pt G20210A and MTHFR C677T gene mutations, which are considered

  16. The Frequency of Factor V Leiden, Prothrombin G20210A and Methylenetetrahydrofolate Reductase C677T Mutations in Migraine Patients

    Directory of Open Access Journals (Sweden)

    Ruhsen Öcal

    2010-12-01

    Full Text Available OBJECTIVE: Migraine is an independent risk factor for ischemic stroke, but its pathophysiology is still unclear. Genetic factors that predispose patients to thrombosis have been studied in patients with migraine to highlight the pathogenesis, but the results remain controversial. In this study, the frequencies of factor V Leiden (FVL, prothrombin (Pt G20210A and methylenetetrahydrofolate reductase (MTHFR C677T mutations were investigated. METHODS: One hundred and sixty patients aged of 15 to 55 years with no history of systemic disease and who had been diagnosed as migraine according to the International Headache Society (IHS diagnostic criteria at Baskent University Hospital Neurology Outpatient Clinics were investigated for FVL, Pt G20210A and MTHFR C677T mutations from their genomic DNA, and the results were compared with those of healthy controls. RESULTS: One hundred and fifty five (96.9% of 160 migraine patients were homozygote normal, 5 (3.1% were heterozygote and none of them were homozygote mutant for FVL. The control group had 9.8% heterozygote individuals but the difference between the percentages was not statistically significant (p> 0.05. There were no homozygote mutant individuals in the Turkish population study in normal subjects like our study. Thirty nine (24.4% of 160 migraine patients were heterozygote and 8 (5% were homozygote mutant for MTHFR C677T. The control group had 37 (34.9% heterozygote and 6 (5.6% homozygote mutant individuals. The difference between the percentages was not statistically significant (p= 0.15. Three (1.9% of 160 migraine patients were heterozygote and 5 (2.9% of the control group were heterozygote mutant for Pt G20210A mutation. The control group had 37 (34.9% heterozygote and 6 (5.6% homozygote mutant individuals. The difference between the percentages was not statistically significant (p= 0.420. CONCLUSION: Our study indicates that FVL, Pt G20210A and MTHFR C677T gene mutations, which are considered

  17. Human Rights in Thick and Thin Societies : The Universal Declaration and Bridging the Gap

    NARCIS (Netherlands)

    Kaplan, Seth Daniel

    2017-01-01

    In an increasingly diverse and multi-polar world, the international human rights field risks losing its legitimacy because of its focus on a particular set of values—autonomy, individualism, equality, choice, secularity, and rationality—that are not necessarily universally shared. There was once a

  18. Internet’s Affects on the Human and Communicational Capitals of the Faculty Members and the PhD and MA Students in Universities

    Directory of Open Access Journals (Sweden)

    Mahdi Montazerghaem

    2009-02-01

    Full Text Available Internet and other modern communication technologies have affected all aspects of the gathering, combining, and transforming knowledge, especially in scientific-educational and research organizations. These processes are parts of the whole intellectual capital in any organization. Intellectual capital is the hidden and intangible property which is oriented toward organizational goals. In the present study, I attempt to reflect on the affects internet has on some particular dimensions of intellectual capital, namely the human and the communicational, in Iran’s universities. According to the theoretical basis, it is shown that internet usage is an important factor in developing organizational intellectual capital (here, in the universities. Results show that human and communicational capitals are differently distributed in various universities. On the other hand, internet accessibility and consumption (type and quantity, as the independent variables of the study, have meaningful affects on human and communicational capitals in all universities. Furthermore, it is noteworthy to say that there are some other factors, as the ranking of the university, department, educational level (for students, and degree (for faculty members, and gender, which intervene in the process. Results show that internet usage, besides other factors as age, gender, marital status, could guide in explanation of the human and communicational capitals’ changes in the universities.

  19. Humanism's Sisyphean Task: Curricular Reform at Brown University during the Second World War

    Science.gov (United States)

    Porwancher, Andrew

    2011-01-01

    In the midst of a curricular debate at Brown University during the Second World War, the faculty's humanists seized the opportunity to pen their views on the nature and purpose of higher education. This investigation reveals humanism as a fragmented force, at once principal and peripheral to the American academy. The central argument of this study…

  20. Are university rankings useful to improve research? A systematic review.

    Science.gov (United States)

    Vernon, Marlo M; Balas, E Andrew; Momani, Shaher

    2018-01-01

    Concerns about reproducibility and impact of research urge improvement initiatives. Current university ranking systems evaluate and compare universities on measures of academic and research performance. Although often useful for marketing purposes, the value of ranking systems when examining quality and outcomes is unclear. The purpose of this study was to evaluate usefulness of ranking systems and identify opportunities to support research quality and performance improvement. A systematic review of university ranking systems was conducted to investigate research performance and academic quality measures. Eligibility requirements included: inclusion of at least 100 doctoral granting institutions, be currently produced on an ongoing basis and include both global and US universities, publish rank calculation methodology in English and independently calculate ranks. Ranking systems must also include some measures of research outcomes. Indicators were abstracted and contrasted with basic quality improvement requirements. Exploration of aggregation methods, validity of research and academic quality indicators, and suitability for quality improvement within ranking systems were also conducted. A total of 24 ranking systems were identified and 13 eligible ranking systems were evaluated. Six of the 13 rankings are 100% focused on research performance. For those reporting weighting, 76% of the total ranks are attributed to research indicators, with 24% attributed to academic or teaching quality. Seven systems rely on reputation surveys and/or faculty and alumni awards. Rankings influence academic choice yet research performance measures are the most weighted indicators. There are no generally accepted academic quality indicators in ranking systems. No single ranking system provides a comprehensive evaluation of research and academic quality. Utilizing a combined approach of the Leiden, Thomson Reuters Most Innovative Universities, and the SCImago ranking systems may provide

  1. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs.

    Science.gov (United States)

    Verrinder, Joy M; Ostini, Remo; Phillips, Clive J C

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students' preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress.

  2. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs

    Science.gov (United States)

    Verrinder, Joy M.; Ostini, Remo; Phillips, Clive J. C.

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students’ preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress. PMID:26934582

  3. LONG-TERM SUCCESS OF AORTOILIAC OPERATION FOR ARTERIOSCLEROTIC OBSTRUCTIVE DISEASE

    NARCIS (Netherlands)

    VANDENAKKER, PJ; VANSCHILFGAARDE, R; BRAND, R; VANBOCKEL, JH; TERPSTRA, JL

    The current retrospective study was performed on 747 patients with aortoiliac obstructive disease who under-went reconstructive operation. Unlike many other centers, the University Hospital Leiden has, throughout the years, maintained the strategy of avoiding the implantation of a prosthesis in

  4. Quantum leap from Dirac and Feynman, across the universe, to human body and mind

    CERN Document Server

    Ivancevic, Vladimir G

    2008-01-01

    This is a unique 21st-century monograph that reveals a basic, yet deep understanding of the universe, as well as the human mind and body - all from the perspective of quantum mechanics and quantum field theory.This book starts with both non-mathematical and mathematical preliminaries. It presents the basics of both non-relativistic and relativistic quantum mechanics, and introduces Feynman path integrals and their application to quantum fields and string theory, as well as some non-quantum applications. It then describes the quantum universe in the form of loop quantum gravity and quantum cosm

  5. Prostaglandins - universal biological regulators in the human body (literature review

    Directory of Open Access Journals (Sweden)

    О. V. Tymoshchuk

    2018-02-01

    Full Text Available Recently, researchers of different industries pay great attention to the problem of prostaglandins. Objective: to study and systematize the basic questions of structure, biological action and metabolism of prostaglandins in the human body and using their analogues in pharmacy through the domestic and foreign literature data analysis. Prostaglandins – biologically active substances which are similar in effect to hormones, but are synthesized in cells of different tissues. Prostaglandins as universal cellular mediators are widely distributed in the body, synthesized in small amounts in almost all tissues, have both local and systemic effects. For each prostaglandin there is a target organ. On chemical structure they are small molecules related to eicosanoids - a group of fat-like substances (lipids. Depending on the chemical structure prostaglandins are divided into series (A, B, C, D, E, F, G, H, I and J and three groups (1–3; type F isomers are to be indicated by additional letters α and β. Prostaglandins have an extremely wide range of physiological effects in the body and have three main functions: supporting, molecular, neurotransmitter. Most prostaglandins interact with specific receptors of plasma membranes, but some prostaglandins (group A can act without receptors. There is no stock of prostaglandins in the body, their life cycle is short, and they are quickly produced in response to biological stimulants exposure, have their effect in extremely small quantity and are rapidly inactivated in the bloodstream. Due to the extremely rapid breakdown of prostaglandins in the body they work near their place of secretion. Preparations of prostaglandins and their derivatives are used in experimental and clinical medicine for abortion and induction of labor, treatment of stomach ulcers, asthma, certain heart diseases, congenital heart defects in newborns, glaucoma, atherosclerosis, rheumatic and neurological diseases, kidney diseases, diabetes

  6. Human Rights, Fundamental Freedoms and Universal Values in International Relations

    Directory of Open Access Journals (Sweden)

    Lev S. Voronkov

    2016-01-01

    Full Text Available The author analyzes the evolution of human rights and fundamental freedoms in domestic political life of individual states and in international relations as well over the latest two centuries. The article traces the role of struggle for liberal political human rights and civilian freedoms in the dismantling of the feudal-absolutist regimes as well as the challenges of radical left-wing (communist and far right-wing (national-socialistic threats to be met by the supporters of liberal political rights and civil freedoms in the interwar period. The list of human rights and fundamental freedoms had constantly been updating in the postwar period, including by the efforts of the UNO and other international organizations, and fixing in different international documents. The author emphasizes the import role of the Conference on Security and Cooperation in Europe (CSCE in transforming the issues of human rights and fundamental freedoms into the essential element of public diplomacy of contemporary states. He traces the process of the increasing utilization of liberal political rights and civilian freedoms, which are usually the effective tools for domestic democratic transformation, within the framework of diplomatic practice of European and North-American states, aimed at ensuring their political and economic interests on the world stage. In this regard the author addresses the attempts of Western countries to legalize "humanitarian"interventions in circumvention of the UN Security Council. The article emphasizes the necessity to replenish the understanding of universal human rights and freedoms by the values, developed both by the international community within the framework of implementing the Millennium Development Goals and by various countries and peoples, which in sum constitute the modern international civilizational baggage.

  7. Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

    DEFF Research Database (Denmark)

    van der Spoel, Evie; Jansen, Steffy W; Akintola, Abimbola A

    2016-01-01

    Reduced growth hormone (GH) signaling has been consistently associated with increased health and lifespan in various mouse models. Here, we assessed GH secretion and its control in relation with human familial longevity. We frequently sampled blood over 24 h in 19 middle-aged offspring of long......-living families from the Leiden Longevity Study together with 18 of their partners as controls. Circulating GH concentrations were measured every 10 min and insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP3) every 4 h. Using deconvolution analysis, we found that 24-h.......39-0.53)] compared with controls [0.66 (0.56-0.77)], indicating tighter control of GH secretion. No significant differences were observed in circulating levels of IGF-1 and IGFBP3 between offspring and controls. In conclusion, GH secretion in human familial longevity is characterized by diminished secretion rate...

  8. Professor Kalkman retires

    NARCIS (Netherlands)

    Baas, Pieter

    1991-01-01

    On 13 December 1990 Prof. Dr. Cornelis (Kees) Kalkman retired from the positions of Professor of Plant Systematics and Scientific Director of the Rijksherbarium/ Hortus Botanicus by presenting his valedictory lecture to the academic community of Leiden University and the assembled Dutch Botanical

  9. Provision and assessment of pharmacology and pharmacotherapy education across an integrated medical school curriculum

    NARCIS (Netherlands)

    Franson, Kari Lanette

    2008-01-01

    The papers presented here detail the approach to provide pharmacology and pharmacotherapy education at the Leiden University Medical Center. First it was decided to use the ability-based education model as the educational method and to have consistent outcomes and assessments throughout the

  10. Bloodcurdling movies and measures of coagulation: Fear Factor crossover trial

    NARCIS (Netherlands)

    Nemeth, Banne; Scheres, Luuk J. J.; Lijfering, Willem M.; Rosendaal, Frits R.

    2015-01-01

    To assess whether, as has been hypothesised since medieval times, acute fear can curdle blood. Crossover trial. Main meeting room of Leiden University's Department of Clinical Epidemiology, the Netherlands, converted to a makeshift cinema. 24 healthy volunteers aged ≤30 years recruited among

  11. The Islamic Bookbinding Tradition. A Book Archaeological Study

    NARCIS (Netherlands)

    Scheper, Catharina Helena (Karin)

    2014-01-01

    The technique of Islamic bookbinding explores the development of the bookbinding tradition in the Islamic world. Based on an assessment of the collections in the University Library Leiden, the various sewing techniques, constructions and the application of covering materials are described in detail.

  12. Airway pathology in COPD : smoking cessation and pharmacological treatment intervention. Results from the GLUCOLD study

    NARCIS (Netherlands)

    Lapperre, Thérèse Sophie

    2010-01-01

    This thesis comprises data from the GLUCOLD study (Groningen Leiden Universities and Corticosteroids in Obstructive Lung Disease), a prospective study in COPD. In chapter 2 is shown that airflow limitation, asthma-like components, exhaled nitric oxide and sputum inflammatory cell counts offer

  13. The Impact of the Universal Declaration of Human Rights on the Study of History

    NARCIS (Netherlands)

    De Baets, Antoon

    There is perhaps no text with a broader impact on our lives than the 1948 Universal Declaration of Human Rights (UDHR). It is strange, therefore, that historians have paid so little attention to the UDHR. I argue that its potential impact on the study of history is profound. After asking whether the

  14. The Ecology of Arts and Humanities Education: Bridging the Worlds of Universities and Museums

    Science.gov (United States)

    Salazar-Porzio, Margaret

    2015-01-01

    In recent years, colleges and universities have been talking seriously about civic learning, but other stakeholders, particularly public arts, culture, and humanities institutions, must be part of the conversation in order to create a context for learning that develops the skills of graduates in robust ways that reflect the full promise of liberal…

  15. Familial longevity is marked by better cognitive performance at middle age: the Leiden Longevity Study.

    Directory of Open Access Journals (Sweden)

    Marjon Stijntjes

    Full Text Available BACKGROUND: Decline in cognitive performance is a highly prevalent health condition in elderly. We studied whether offspring of nonagenarian siblings with a familial history of longevity, perform better on cognitive tests compared to their partners as controls. This is relevant since it could provide insights into determinants underlying decline in cognitive performance. METHODS: Cross-sectional analysis within the longitudinal cohort of the Leiden Longevity Study consisting of middle-aged offspring of nonagenarian siblings together with their partners (n = 500, mean age (SD 66.3 (6.1 and 65.7 (7.2 years, respectively as controls. Memory function, attention and processing speed were tested using the 15-Picture Learning Test, Stroop test and Digit Symbol Substitution Test. Data were analyzed with regression adjusted for age, gender, years of education and additionally for diabetes mellitus, cardiovascular diseases, alcohol use, smoking, inflammatory markers and apolipoprotein E genotype. Robust standard errors were used to account for familial relationships among the offspring. RESULTS: Cognitive performance was worse at higher calendar age (p<0.001, all except Stroop test part 1. The offspring performed better compared to their partners on trial 3 (p = 0.005, the immediate (p = 0.016 and delayed (p = 0.004 recall of the 15-Picture Learning Test as well as on the interference and combined interference score of the Stroop test (p = 0.014 and p = 0.036, respectively in the fully adjusted model. The difference between offspring and partners was estimated to be more than three years according to the observed difference in calendar age. CONCLUSIONS: Offspring of nonagenarian siblings with a familial history of longevity have better cognitive performance compared to the group of their partners of comparable age. This effect is independent of age-related diseases and known possible confounders. Possible explanations might be differences in subclinical

  16. [People, the environment and health: the "Oneness" of human health from the perspective of universal life presented in "Changes"].

    Science.gov (United States)

    Yang, Ke-Ping

    2008-12-01

    This paper aimed to expand the paradigm of nursing and expand the essential factors of nursing theories beyond "environment" to encompass universal life. While individuals live between the sky and earth, we are an inseparable part of the universe. "Health" is derived from a oneness that embraces the body, mind and spirit. The human body contains the wisdom of the universe, known in Chinese philosophy as the wisdom of "Changes". The body has its own consciousness and possesses great powers of self-healing. Healthiness is the original condition of life. Modern medicine assumes sickness to be a natural phenomenon, with the essential nature of "Changes" neglected as a universal law for maintaining health. Dr. Sun, a renowned physician from the Tang Dynasty, was quoted as saying "Knowing Changes is the prerequisite of knowing medicine." Another saying holds that, "Every word and every sentence in the Book of Changes is an indicator of medicine." Much emphasis has been placed on the relationship between "Changes" and "medicine" in the past. This paper elaborates the relationship between nature and human health in order to provide a clear understanding of the nature of true health, described from the perspectives of medicine and "Changes", an evaluation of modern medical science and the oneness of body-mind-spirit, which is the reality of health. The human body is thus a reflection of the mind and spirit, while the mind and spirit is the "inner body". The body is a highly intelligent organism that truly reflects our inner world. Our inner world is also displayed through physical symptoms. As human suffering is caused by separation from our inner life, the only path to enjoying a healthy and joyful life is to achieve a oneness between our body-mind-spirit. Such is a universal law, which is called "Changes" or "Oneness".

  17. Kyoto University-National Taiwan University International Symposium "Social Cognitive Biology on Representation of Environment

    OpenAIRE

    Saiki, Jun

    2016-01-01

    Sponsored by Kyoto University, National Taiwan University; Cosponsored by Unit for Advanced Studies of the Human Mind, Kyoto University, Kokoro Research Center, Kyoto University, Supported by Supporting Program for InteRaction-based Initiative Team Studies (SPIRITS), Kyoto University

  18. Rhizostomeen von Manila

    NARCIS (Netherlands)

    Stiasny, G.

    1924-01-01

    Die hier beschriebene kleine Scyphomedusen-Sammlung wurde von Herrn Director P. B. Sivickis, Dept. of Zoology, University of Philippines, Manila, dem Rijksmuseum van Natuurlijke Historie in Leiden überwiesen. Das Material wurde im December 1922 in Manila-bay gefischt und befindet sich in bestem

  19. Beyond the galaxy how humanity looked beyond our milky way and discovered the entire Universe

    CERN Document Server

    Siegel, Ethan

    2016-01-01

    A look up at the night sky reveals a treasury of wonders. Even to the naked eye, the Moon, stars, planets, the Milky Way and even a few star clusters and nebulae illuminate the heavens. For millennia, humans struggled to make sense of what's out there in the Universe, from all we can see to that which lies beyond the limits of even our most powerful telescopes. Beyond the Galaxy traces our journey from an ancient, Earth-centered Universe all the way to our modern, 21st century understanding of the cosmos. Touching on not only what we know but also how we know it, Ethan Siegel takes us to the very frontiers of modern astrophysics and cosmology, from the birth of our Universe to its ultimate fate, and everything in between.

  20. The Geneva University Global Health and Human Rights Summer School: A 5-Year Intercultural Collaborative Experience

    Directory of Open Access Journals (Sweden)

    Philippe Chastonay

    2018-05-01

    Full Text Available Education and training in human rights has been set as a priority by the United Nations. Health and human rights are closely related. Training professionals from various backgrounds in human rights might ultimately contribute to improve the health of individuals and communities. We present the 5 years’ experience with a 3-week residential Global Health and Human Rights Course developed at the University of Geneva and implemented with the support/participation of international organizations (IOs and non-governmental organizations active in the health and human rights sector. Over the years, roughly 150 students from 43 nationalities, with many different educational backgrounds, attended the course. The male/female ratio was 1/5. The adopted educational approach was multifold and comprised lectures from academics and experts with field experience, group work, individual case studies, journal clubs, and site visits. Evaluation data show that site visits at IOs were highly appreciated as well as networking opportunities among students, with academics and experts with field experience. The variety of topics discussed was, at times, “too much”; yet, it allowed students to measure the extent of the challenges the field is facing. The adopted active learning approach facilitated the exchange of experiences among students and allowed them to get acquainted with different cultural sensitivities. The Global Health and Human Rights Summer-School of the University of Geneva allowed its participants, coming from all over the world, to identify challenges of the interlinked fields of health and human rights, reflect upon their underlying causes, and imagine possible solutions. Sharing our experience will hopefully help passionate educators around the world to develop similar programs.

  1. The Geneva University Global Health and Human Rights Summer School: A 5-Year Intercultural Collaborative Experience.

    Science.gov (United States)

    Chastonay, Philippe; Mpinga, Emmanuel K

    2018-01-01

    Education and training in human rights has been set as a priority by the United Nations. Health and human rights are closely related. Training professionals from various backgrounds in human rights might ultimately contribute to improve the health of individuals and communities. We present the 5 years' experience with a 3-week residential Global Health and Human Rights Course developed at the University of Geneva and implemented with the support/participation of international organizations (IOs) and non-governmental organizations active in the health and human rights sector. Over the years, roughly 150 students from 43 nationalities, with many different educational backgrounds, attended the course. The male/female ratio was 1/5. The adopted educational approach was multifold and comprised lectures from academics and experts with field experience, group work, individual case studies, journal clubs, and site visits. Evaluation data show that site visits at IOs were highly appreciated as well as networking opportunities among students, with academics and experts with field experience. The variety of topics discussed was, at times, "too much"; yet, it allowed students to measure the extent of the challenges the field is facing. The adopted active learning approach facilitated the exchange of experiences among students and allowed them to get acquainted with different cultural sensitivities. The Global Health and Human Rights Summer-School of the University of Geneva allowed its participants, coming from all over the world, to identify challenges of the interlinked fields of health and human rights, reflect upon their underlying causes, and imagine possible solutions. Sharing our experience will hopefully help passionate educators around the world to develop similar programs.

  2. [Cultural diversity and pluralism in the Universal Declaration on Bioethics and Human Rights].

    Science.gov (United States)

    Romeo Casabona, Carlos María

    2011-01-01

    The Universal Declaration on Bioethics and Human Rights represents a significant milestone in the history of Law, particularly in the application of International Law to an important area of human activity, namely the medical sciences, the life sciences and the technologies which, linked to both, can be applied to human relations. In parallel with this, and as will be analysed in this article, the Declaration has involved adopting a clear position regarding cultural diversity and pluralism in relation to Biomedicine. In this paper the author highlights the fact that perspectives have been opened which have hardly been explored concerning Biomedicine, such as the recognition of the value and respect which cultural diversity (multiculturalism), economic and social diversity deserve in relation to the issues covered by the Declaration, and the acceptance that the owners of the rights are not only individuals, but can also be groups.

  3. Individualized Biomathematical Modeling of Fatigue and Performance

    Science.gov (United States)

    2008-05-29

    Interactions and Transitions 53 New Discoveries , Inventions, or Patent Disclosures 56 FA9550-06-1-0055 Individualized Biomathematical Modeling of Fatigue...Old Dominion University, not supported on grant) Daniel J. Mollicone, Ph.D. ( Pulsar Informatics, Inc., not supported on grant) Christopher G...Mott, M.S. ( Pulsar Informatics, Inc., not supported on grant) Erik Olofsen, M.S. (Leiden University, the Netherlands, not supported on grant

  4. Museums theme – Quest for Absolute Zero: A Human Story about Rivalry and Cold

    Directory of Open Access Journals (Sweden)

    Dirk van Delft

    2017-11-01

    Full Text Available In 2008 Rijksmuseum Boerhaave organised an exhibition on the occasion of the centennial of the liquefaction of helium by Kamerlingh Onnes in Leiden. Quest for Absolute Zero was the first major temporary exhibition aimed at new target groups. Therefore the focus was on the human scale and the colourful story behind the ‘man of Absolute Zero’. The fierce competition with James Dewar from the Royal Institution was also highlighted. The outcome of Quest for Absolute Zero was extremely positive for Rijksmuseum Boerhaave in terms of visitor numbers, media coverage, collaborations and side events. The project also proved to be a very useful lever for the renewal of the permanent exhibition, scheduled to open in December 2017.

  5. The University Rover Challenge: A competition highlighting Human and Robotic partnerships for exploration

    Science.gov (United States)

    Smith, Heather; Duncan, Andrew

    2016-07-01

    The University Rover Challenge began in 2006 with 4 American college teams competing, now in it's 10th year there are 63 teams from 12 countries registered to compete for the top rover designed to assist humans in the exploration of Mars. The Rovers compete aided by the University teams in four tasks (3 engineering and 1 science) in the Mars analog environment of the Utah Southern Desert in the United States. In this presentation we show amazing rover designs with videos demonstrating the incredible ingenuity, skill and determination of the world's most talented college students. We describe the purpose and results of each of the tasks: Astronaut Assistant, Rover Dexterity, Terrain maneuvering, and Science. We explain the evolution of the competition and common challenges faced by the robotic explorers

  6. The induction of thyroid-gland tumours by ionizing radiation

    International Nuclear Information System (INIS)

    Daal, W.A.J. van.

    1981-01-01

    The study reported in this thesis formed part of an investigation on radiation-induced tumours in a sample of the patients given radiation therapy in the head and neck region for benign diseases at the Leiden University Hospital between 1932 and 1963. To find out whether it would be useful to trace and examine all patients, a random sample comprising 25% of the irradiated cohort was examined for (induced) tumours of the skin, mouth and throat, and the thyroid and parathyroid glands. The present study was confined to induced tumours of the thyroid gland. The literature is reviewed and analysed and the study described. With respect to the scientific aspects, it may be concluded that if the duration of followup is not taken into account, the prevalence of thyroid gland nodules and non-occult carcinomas in the surviving Leiden patients is roughly the same as that found in comparable studies done elsewhere, but for equivalent follow-up periods the incidence of both nodules and carcinomas is much lower for Leiden. (Auth.)

  7. Through measurement to knowledge the selected papers of Heike Kamerlingh onnes 1853–1926

    CERN Document Server

    Goudaroulis, Yorgos

    1991-01-01

    "Tile; D'apC:Tile; l. DpWTa ()coi 7rpo7rapod)w £ D'T}K,mi'. "between us and Goodness the gods have placed the sweat of our brows". This quote from Isiodos, the first lyrical poet, is jotted on a sheet of paper found among the papers of Heike Kamerlingh Onnes at the Boerhaave Museum, Leiden. On this same sheet, one can also read quotes from Schiller, Goethe, Shakespeare, Homer, Pindar and Dante. Each quote is for somebody or something. It appears to have been a game played at least by Ehrenfest and Crommelin -an unmistakable sign of these two physicists's deep culture. This particular quote was for the "Werkplaats", the Physical Laboratory of the University of Leiden. Our purpose in putting together the Selected Papers of its first Director, Kamerlingh Onnes (1853-1926), is to try and articulate the dominant trends of a different type of culture at Leiden: its physics culture during the years that established low temperature physics as a distinct branch of physics. Our aims in choosing the particular papers a...

  8. Bιβλιοκρισία του: V. SYROS, Die Rezeption der aristotelischen politischen Philosophie bei Marsilius von Padua. Eine Untersuchung zur ersten Diktion des Defensor pacis [Studies in Medieval and Reformation Traditions, ed. by A. C. Gow, v. 134], Leiden, 2007

    Directory of Open Access Journals (Sweden)

    Στυλιανός ΛΑΜΠΑΚΗΣ

    2012-01-01

    Full Text Available   Βιβλιοκρισία του : V. SYROS, Die Rezeption der aristotelischen politischen Philosophie bei Marsilius von Padua. Eine Untersuchung zur ersten Diktion des Defensor pacis. [Studies in Medieval and Reformation Traditions, edited by Andrew Colin Gow, volume 134], Brill, Leiden-Boston 2007, σελ. X+364, ISSN 1573-4188

  9. Existing data sources in clinical epidemiology: the Scandinavian Thrombosis and Cancer Cohort

    Directory of Open Access Journals (Sweden)

    Jensvoll H

    2015-09-01

    Full Text Available Hilde Jensvoll,1,2 Marianne T Severinsen,3,4 Jens Hammerstrøm,5 Sigrid K Brækkan,1,2 Søren R Kristensen,4,6 Suzanne C Cannegieter,7 Kristine Blix,1,2 Anne Tjønneland,8 Frits R Rosendaal,1,7,9 Olga Dziewiecka,1 Kim Overvad,10,11 Inger Anne Næss,12 John-Bjarne Hansen1,21Department of Clinical Medicine, KG Jebsen – Thrombosis Research and Expertise Center (TREC, UiT – The Arctic University of Norway, 2Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway; 3Department of Hematology, Aalborg University Hospital, 4Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; 5Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; 6Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark; 7Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; 8Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark; 9Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands; 10Department of Cardiology, Aalborg University Hospital, Aalborg, 11Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark; 12Department of Hematology, Trondheim University Hospital, Trondheim, NorwayBackground: Although venous thromboembolism (VTE is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian Thrombosis and Cancer (STAC Cohort was established by merging individual data from three large Scandinavian cohorts (The Tromsø Study, the second Nord-Trøndelag Health Study, and the Danish Diet, Cancer and Health Study. Here, we present the profile of the STAC cohort and provide age-specific incidence rates of VTE and cancerMethods: The STAC cohort includes 144,952 subjects aged 19–101 years

  10. MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota.

    Science.gov (United States)

    Zhang, Xu; Ning, Zhibin; Mayne, Janice; Moore, Jasmine I; Li, Jennifer; Butcher, James; Deeke, Shelley Ann; Chen, Rui; Chiang, Cheng-Kang; Wen, Ming; Mack, David; Stintzi, Alain; Figeys, Daniel

    2016-06-24

    The gut microbiota has been shown to be closely associated with human health and disease. While next-generation sequencing can be readily used to profile the microbiota taxonomy and metabolic potential, metaproteomics is better suited for deciphering microbial biological activities. However, the application of gut metaproteomics has largely been limited due to the low efficiency of protein identification. Thus, a high-performance and easy-to-implement gut metaproteomic approach is required. In this study, we developed a high-performance and universal workflow for gut metaproteome identification and quantification (named MetaPro-IQ) by using the close-to-complete human or mouse gut microbial gene catalog as database and an iterative database search strategy. An average of 38 and 33 % of the acquired tandem mass spectrometry (MS) spectra was confidently identified for the studied mouse stool and human mucosal-luminal interface samples, respectively. In total, we accurately quantified 30,749 protein groups for the mouse metaproteome and 19,011 protein groups for the human metaproteome. Moreover, the MetaPro-IQ approach enabled comparable identifications with the matched metagenome database search strategy that is widely used but needs prior metagenomic sequencing. The response of gut microbiota to high-fat diet in mice was then assessed, which showed distinct metaproteome patterns for high-fat-fed mice and identified 849 proteins as significant responders to high-fat feeding in comparison to low-fat feeding. We present MetaPro-IQ, a metaproteomic approach for highly efficient intestinal microbial protein identification and quantification, which functions as a universal workflow for metaproteomic studies, and will thus facilitate the application of metaproteomics for better understanding the functions of gut microbiota in health and disease.

  11. Open Letter Regarding the University of Minnesota's Program on Human Sexuality and Sexual Attitude Reassessment Seminars

    Science.gov (United States)

    Hunt, William C.; Nelson, James

    1976-01-01

    This article contains a letter which questions the value and ethics of the Program on Human Sexuality (University of Minnesota) and also contains the response to the letter by a member of the Theological-Ethical Task Force which sponsors the program. (Author)

  12. Travel, infection and immunity

    NARCIS (Netherlands)

    Soonawala, Darius

    2016-01-01

    Preface: The content of this thesis is based on research that was conducted at the travel and vaccination clinic at Leiden University Medical Centre (LUMC). This clinic provides pre-travel care to the general population, and to special groups of travellers, such as patients who use

  13. Researching Africa : Explorations of everyday African encounters

    NARCIS (Netherlands)

    Bruijn, de M.E.; Merolla, D.

    2010-01-01

    The studies in this volume are the result of research carried out by students of the Research Masters in African Studies (RMAS) at Leiden University who graduated in 2008. The studies cover such areas as conflict, democracy, migration, urban and rural studies, language, communication and youth. An

  14. The return of pedagogic: On the Dutch translation of Klaus Mollenhauer’s Vergessene Zusammenhänge

    NARCIS (Netherlands)

    W. Pols

    2014-01-01

    In the seventies, the translators of Vergessene Zusammenhänge (Ciske Balhan and myself) studied education at the University of Leiden. We specialized in social-educational theory (‘social pedagogic’) and we studied Klaus Mollenhauer. He was a well-known educationalist who conceptualized the field of

  15. Preface

    NARCIS (Netherlands)

    Binsbergen, van W.M.J.; Geschiere, P.L.; Binsbergen, van W.M.J.; Geschiere, P.L.

    1985-01-01

    Revised version of a book first published in 1982 in Dutch entitled "Oude produktiewijzen en binnendringend kapitalisme" by the Free University, Amsterdam, in association with the African Studies Centre, Leiden. The modern history of Africa can be seen in Marxist terms as a process by which the

  16. Egypt in material and mind : the use and perception of Aegyptiaca in Roman domestic contexts of Pompeii

    NARCIS (Netherlands)

    Mol, Eva Martine

    2015-01-01

    This dissertation was written within the NWO VIDI project ‘Cultural innovation in a globalising society, Egypt in the Roman world’, (Faculty of Archaeology, Leiden University) directed by dr. Miguel John Versluys. The general aim of this project is devoted to the understanding of the different

  17. In memoriam Prof. Dr J.T. Wiebes (1931-1999), evolutionary biologist and systematic entomologist

    NARCIS (Netherlands)

    Bruggen, van A.C.; Achterberg, van C.

    2000-01-01

    Born on 13 September 1931 in Rotterdam, Jacobus Theodorus [Koos] Wiebes read biology at Leiden University where he obtained his Ph.D. in 1963 on studies of Indo-Australian fig wasps. He started working on spiders (Lycosidae, Pisauridae) and beetles (Carabidae, Cetoniidae, Helodidae), but he earned

  18. Translating China : Henri Borel (1869-1933)

    NARCIS (Netherlands)

    Heijns, A.J.

    2016-01-01

    This thesis investigates how Dutch sinologist Henri Borel ‘translated’ China, by examining his renditions of Chinese literature and the writings about China that he produced over a period of forty years. Borel studied Hokkien Chinese at Leiden University and in Xiamen toward a career as Chinese

  19. The natural antibody repertoire of sharks and humans recognizes the potential universe of antigens.

    Science.gov (United States)

    Adelman, Miranda K; Schluter, Samuel F; Marchalonis, John J

    2004-02-01

    In ancestral sharks, a rapid emergence in the evolution of the immune system occurred, giving jawed-vertebrates the necessary components for the combinatorial immune response (CIR). To compare the natural antibody (NAb) repertoires of the most divergent vertebrates with the capacity to produce antibodies, we isolated NAbs to the same set of antigens by affinity chromatography from two species of Carcharhine sharks and from human polyclonal IgG and IgM antibody preparations. The activities of the affinity-purified anti-T-cell receptor (anti-TCR) NAbs were compared with those of monoclonal anti-TCR NAbs that were generated from a systemic lupus erythematosus patient. We report that sharks and humans, representing the evolutionary extremes of vertebrate species sharing the CIR, have NAbs to human TCRs, Igs, the human senescent cell antigen, and to numerous retroviral antigens, indicating that essential features of the combinatorial repertoire and the capacity to recognize the potential universe of antigens is shared among all jawed-vertebrates.

  20. THE MANAGEMENT AND THE DEVELOPMENT OF THE HUMAN RESOURCES IN THE PRE-UNIVERSITY EDUCATION

    Directory of Open Access Journals (Sweden)

    Luminita, ANDONE

    2014-11-01

    Full Text Available Through the management of the human resources it is provided the necessity of the workforce in an institution, on staff categories with the view of achieving the activities and the obtaining of the expected results. The descentralization of the budget institutions makes the obtaining of some principles of the human resources management to be essential so that they create the conditions of involving and participating in the institution activity, as we wish to live in a society where the fundamental values are creativity, liberty, pluralism and tolerance. The pre-university education institution(kindergartens, schools and high schools are not provided with a human resources manager. The descentralized management of the human resources level of the School County Inspectorate, the lack of a clear policy in the domain of the human resources ( at the level of the School County Inspectorate even if there is a management department of the human resources, those who work in this department do not have the necessary qualification, being selected teaching staff on certain criteria, and the unprofessional involvement of the local authorities, these being disruptive factors of the training-educational process.

  1. THE MANAGEMENT AND THE DEVELOPMENT OF THE HUMAN RESOURCES IN THE PRE-UNIVERSITY EDUCATION

    Directory of Open Access Journals (Sweden)

    Luminita, ANDONE

    2014-07-01

    Full Text Available Through the management of the human resources it is provided the necessity of the workforce in an institution, on staff categories with the view of achieving the activities and the obtaining of the expected results. The descentralization of the budget institutions makes the obtaining of some principles of the human resources management to be essential so that they create the conditions of involving and participating in the institution activity, as we wish to live in a society where the fundamental values are creativity, liberty, pluralism and tolerance. The pre-university education institution(kindergartens, schools and high schools are not provided with a human resources manager. The descentralized management of the human resources level of the School County Inspectorate, the lack of a clear policy in the domain of the human resources ( at the level of the School County Inspectorate even if there is a management department of the human resources, those who work in this department do not have the necessary qualification, being selected teaching staff on certain criteria, and the unprofessional involvement of the local authorities, these being disruptive factors of the training-educational process.

  2. Implementation of the human talent management through competencies model in a university in Metropolitan Lima

    Directory of Open Access Journals (Sweden)

    Juan C. Rodríguez

    2015-12-01

    Full Text Available This article is a work proposal that aims to describe the methodology proposed by the Management of Personnel Management from a university in Lima, to implement a management model based on competencies which traceability involves various technical HR processes practiced in the organization and is aligned to institutional outcomes defined in the balance score card. In order to do it, various literature sources were consulted, and the websites of the top ten universities worldwide to identify benchmarks were visited. Generic skills, competencies level, specific skills, competencies dictionary and graduation for each of the managements, occupational categories and administrative headquarters of the University: as a result, the following definitions and elements were obtained. In this way, the institution develops a tool to guide how and to what extent human resources should have and develop skills to achieve specific organizational results

  3. The frequency of β-globin gene haplotypes, α-thalassemia and genetic polymorphisms of methylenetetrahydrofolate reductase, factor V Leiden and prothrombin genes in children with sickle cell disease in Rio de Janeiro, Brazil Frequência dos haplótipos da globina beta, da talassemia alfa e dos polimorfismos genéticos dos genes da metilenotetrahidrofolato redutase, do fator V Leiden e da protrombina em crianças com doença falciforme no Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Isaac L. Silva Filho

    2010-02-01

    Full Text Available A freqüência dos haplótipos beta S e beta C do gene da globina e a prevalência de talassemia alfa e de mutações nos genes da metilenotetrahidrofolato redutase (MTHFR-C677T, do fator V de Leiden e da protrombina (G20210A foi estudada em crianças com doença falciforme do Rio de Janeiro. O haplótipo Bantu foi o mais freqüente (65,9%, 21,2% das crianças (18% heterozigotas e 3% homozigotas apresentam talassemia com mutação alfa 3.7kb, ao contrário da mutação alfa 4.2kb que não foi encontrada. Os alelos 677CT e 677TT da MTHFR foram observados em 20,2% e 4,8%, respectivamente. Os haplótipos Camarões, Árabe-Indiano e Senegal não foram detectados na amostra estudada, bem como mutações no gene do fator V de Leiden e da protrombina. Somente o haplótipo beta C CI foi observado. Esse é o primeiro estudo realizado em uma amostra proveniente do Programa de Triagem Neonatal para Hemoglobinopatias do estado do Rio de Janeiro. Apesar do Rio de Janeiro ser a segunda maior cidade brasileira e seus habitantes expressarem o elevado grau de miscigenação ocorrida no país, nossos resultados ainda coincidem com os registros históricos dos fluxos migratórios do gene beta S para o Brasil, bem como refletem a forte influência de indivíduos de origem africana na população do Rio de Janeiro.

  4. The genus Stackhousia in the Malay Archipelago

    NARCIS (Netherlands)

    Brouwer, F.I.

    1938-01-01

    This publication is based on herbarium, materials which were kindly placed at the author’s disposal by the Directors of the Herbarium of the Buitenzorg Botanic Garden (B), the Leiden National Herbarium (L), the Herbarium of the Utrecht University (U), and the Herbarium of the Berlin-Dahlem Botanical

  5. General linguistics and the study of Dutch. The case of C.F.P. Stutterheim (1903-1991)

    NARCIS (Netherlands)

    Noordegraaf, J.

    The mingling of linguistics and philosophy of language is characteristic of structuralism in the Netherlands. In this paper the case of the Dutch linguist C.F.P. Stutterheim (1903-1991), professor of Dutch language in the University of Leiden, is used to examine the extent to which this alliance

  6. Jona Willem te Water (1740-1822) : historicus en theoloog tussen traditie en Verlichting

    NARCIS (Netherlands)

    Mooij, Jacobus Daniël de

    2008-01-01

    Jona Willem te Water (1740-1822), a professor at Leiden University, was a man of influence in the Dutch Reformed Church, in many learned societies, in academic theology, and in Dutch historiography. He started his career as a Reformed minister in the province of Zeeland. His main historiographical

  7. Universal Declaration of Human Rights, A Lay Version for the Common Man, Woman and Child.

    Science.gov (United States)

    Tankard, Alice Doumanian

    This lay version of the Universal Declaration of Human Rights (the original version was adopted by the General Assembly of the United Nations in 1948) has been written in simplified vocabulary to make it understandable to a wider range of ages and reading abilities. The declaration consists of a preamble followed by a listing of 30 goals common to…

  8. Heterosybtypic T-cell immunity to influenza in humans: challenges for universal T-cell influenza vaccines

    Directory of Open Access Journals (Sweden)

    Saranya eSridhar

    2016-05-01

    Full Text Available Influenza A virus (IAV remains a significant global health issue causing annual epidemics, pandemics and sporadic human infections with highly pathogenic avian or swine influenza viruses. Current inactivated and live vaccines are the mainstay of the public health response to influenza although vaccine efficacy is lower against antigenically distinct viral strains. The first pandemic of the 21st century underlined the urgent need to develop new vaccines capable of protection against a broad range of influenza strains. Such universal influenza vaccines are based on the idea of heterosubtypic immunity wherein immune responses to epitopes conserved across IAV strains can confer protection against subsequent infection and disease. T-cells recognising conserved antigens are a key contributor to reducing viral load and limiting disease severity during heterosubtypic infection in animal models. Recent studies undertaken during the 2009 H1N1 pandemic provided key insights into the role of cross-reactive T-cells in mediating heterosubtypic protection in humans. This review focuses on human influenza to discuss the epidemiological observations that underpin cross-protective immunity, the role of T-cells as key players in mediating heterosubtypic immunity including recent data from natural history cohort studies and the ongoing clinical development of T-cell inducing universal influenza vaccines. The challenges and knowledge gaps for developing vaccines to generate long-lived protective T-cell responses is discussed.

  9. Patient experiences with self-monitoring renal function after renal transplantation: results from a single-center prospective pilot study

    Directory of Open Access Journals (Sweden)

    van Lint CL

    2015-12-01

    Full Text Available Céline L van Lint,1 Paul JM van der Boog,1 Wenxin Wang,2,3 Willem-Paul Brinkman,2 Ton JM Rövekamp,3 Mark A Neerincx,2 Ton J Rabelink,1 Sandra van Dijk1,4 1Department of Nephrology, Leiden University Medical Centre (LUMC, Leiden, 2Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, Delft, 3Department of Technology in Healthcare, Prevention and Health, Dutch Organization for Applied Scientific Research (TNO, Leiden, 4Department of Health, Medical and Neuropsychology, Faculty of Social and Behavioural Sciences, Leiden University, Leiden, the Netherlands Background: After a kidney transplantation, patients have to visit the hospital often to monitor for early signs of graft rejection. Self-monitoring of creatinine in addition to blood pressure at home could alleviate the burden of frequent outpatient visits, but only if patients are willing to self-monitor and if they adhere to the self-monitoring measurement regimen. A prospective pilot study was conducted to assess patients’ experiences and satisfaction.Materials and methods: For 3 months after transplantation, 30 patients registered self-measured creatinine and blood pressure values in an online record to which their physician had access to. Patients completed a questionnaire at baseline and follow-up to assess satisfaction, attitude, self-efficacy regarding self-monitoring, worries, and physician support. Adherence was studied by comparing the number of registered with the number of requested measurements.Results: Patients were highly motivated to self-monitor kidney function, and reported high levels of general satisfaction. Level of satisfaction was positively related to perceived support from physicians (P<0.01, level of self-efficacy (P<0.01, and amount of trust in the accuracy of the creatinine meter (P<0.01. The use of both the creatinine and blood pressure meter was considered pleasant and useful, despite the level of trust in the

  10. Human body donation in Thailand: Donors at Khon Kaen University.

    Science.gov (United States)

    Techataweewan, N; Panthongviriyakul, C; Toomsan, Y; Mothong, W; Kanla, P; Chaichun, A; Amarttayakong, P; Tayles, N

    2018-03-01

    Culture, society and spirituality contribute to variability in the characteristics of human body donors and donation programmes worldwide. The donors and the body donation programme at Khon Kaen University, northeast Thailand, reflect all these aspects of Thailand, including the status accorded to the donors and the ceremonial acknowledgement of the donors and their families. Data from the programme records and from surveys of samples of currently registering donors and recently received donor bodies are analysed to define the characteristics of both registering and received donors, including motivation, demography, socio-economic status, health, and use of the bodies. The body donation programme at Khon Kaen University currently has a very high rate of registration of body donors, with gender and age differences in the patterns of donation. Registrants include more females than males, a long-standing pattern, and are an average age of 50 years. The bodies of 12% of registrants are received after death and include more males than females. Both sexes are of an average age of 69 years. Males had registered their donation eight years prior to death and females ten years prior. Current registrants identified altruistic motives for their decision to donate, although the coincidence of body donation by a highly revered monk with a surge in donations in 2015 suggests that Buddhism plays a primary role in motivation. The opportunity to make merit for donors and their families, and respect shown to donors and the nature of the ceremonies acknowledging the donors and their families, including the use of the Royal Flame at the cremation ceremony, all contribute to decisions to donate. The characteristics of body donors and the body donation programme at Khon Kaen University are reflective of Thai society and the centrality of Buddhism to Thai culture. Copyright © 2017 Elsevier GmbH. All rights reserved.

  11. Evaluation of home collection performed by a human milk bank in a university hospital in Brazil.

    Directory of Open Access Journals (Sweden)

    Glória Menezes

    2014-05-01

    Full Text Available Objective. Evaluation of procedures during household milking and transport of human milk associated with their quality control. Materials and methods. 48 donors registered in the Human Milk Bank of the Clinics Hospital of the Federal University at Uberlândia. Observations were made during home visits. A checklist was elaborated according to the technical standards for human milk banks, been associated with  physical-chemical, and microbiological controls. The chi-square test, logistic regression and Spearman test (p menor que 0.05 were used for data analysis. Results. The results suggest that most donors assimilated the guidelines of the milk bank staff and procedures were satisfactorily performed. Conclusion. It could be demonstrated that milking and home collection are safe and effective ways for obtaining donated human milk.

  12. Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

    NARCIS (Netherlands)

    Morrison, M.C.; Kleemann, R.; Koppen, A. van; Hanemaaijer, R.; Verschuren, L.

    2018-01-01

    Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic

  13. Iz žyttievoho šliaxu ognoho istoryka (movoznavči zmanhannia Heuzinxy zamolodu)

    NARCIS (Netherlands)

    Noordegraaf, J.

    2006-01-01

    Having learned some Hebrew and Arabic at grammar school, Johan Huizinga (1872-1945) intended to study Arabic in Leiden, but his father did not approve of this idea for financial reasons. So, the young Huizinga enrolled as a student of Dutch at Groningen University in September 1891. In those days,

  14. Contemporary Salafism and the Rightly Guided Caliphate: Why Is It Emulated and What Was Its Reality?

    Science.gov (United States)

    2013-12-01

    Spuler, The Muslim World, Part I: The Age of the Caliphs, trans. F. R. C. Bagley (Leiden, Netherlands: E.J. Brill, 1960), 31. 70 Ibid., 19, 24; Crone...Interpretation. London: Cambridge University Press, 1971. Spuler, Bertold. The Muslim World, Part I: The Age of the Caliphs. Trans. F. R. C. Bagley

  15. Proeven over den invloed van golven op een strand. In verband met enkele waarnemingen aan de Nederlandsche kust

    NARCIS (Netherlands)

    Timmermans, P.D.

    1933-01-01

    In order to throw more light on the formation of submarine bars and offshore bars or barrier beaches and the minor shore forms beach cusps and ripple marks a series of experiments was made in the new laboratory for experimental geology of the Geological Institution of the University at Leiden. The

  16. The Rijksherbarium, 150 years old

    NARCIS (Netherlands)

    NN,

    1979-01-01

    On March 29 and 30, 1979, the Rijksherbarium at Leiden commemorated in a modest way its foundation by King William I, 150 years ago. On the first day of the celebration a large company, including several distinguished foreign botanists, gathered in the old central building of the University for a

  17. Knowledge, attitudes, and perception towards human papillomavirus among university students in Pakistan

    Directory of Open Access Journals (Sweden)

    Tahir Mehmood Khan

    2016-12-01

    Full Text Available This cross-sectional study comprises a questionnaire-based survey regarding knowledge about human papillomavirus and its vaccine among students in different educational fields at public and private universities in the city of Lahore in Pakistan. A 26-item questionnaire was used to attain the objective of this study. The reliability of this tool was assessed using Cronbach's alpha (0.79 and the Kaiser-Meyer-Olkin value was 0.827. The response rate to the survey was 78.0%, of whom the majority (74.9% were females and 308 (79% were single (median age=23 years. While assessing the respondents' knowledge about HPV, 223(57% students reported that they had already heard of HPV (human papillomavirus and nearly 215 (55% reported that HPV causes cervical cancer and can infect both men and women. Gender and field of study were two main factors found influencing the respondents' knowledge about HPV. Moreover, students' understanding about the mode of transmission of HPV was cursory: 40.51% said they did not know how HPV is transmitted, 133 (34.10% stated that HPV spreads through the exchange of bodily fluids, and 22 (5.64% selected cough/sneezing. In terms of prevention, 175 (44.87% students stated that HPV can be prevented by vaccination, 30.0% reported sexual abstinence, 21.54% using condoms, and nearly 5.38% disclosed use of antibiotics. Addressing the knowledge of students regarding HPV vaccine, nearly 53% stated there is no vaccine against HPV and almost 64% rejected the statement that HPV vaccine prevents cervical cancer. In addition, students reported that they will be more than willing to get vaccinated for HPV if their physician recommend them (RII=0.74 followed by parents (RII=0.69. The results of this study revealed a poor understanding among respondents about the health problems associated with HPV, its prevention, modes of transmission and arability of HPV vaccine in Pakistan. Keywords: Human papillomavirus, Vaccine, Knowledge, Attitude

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    Gerard Termorshuizen

    1999-01-01

    Full Text Available - Adriaan Bedner, Joachim Sterly, Simbu plant-lore; Plants used by the people in the Central Highlands of New Guinea; Volume 1: The people and their plant-lore; Volume 2: Botanical survey of Simbu plants; Volume 3: Ethnographical key. Berlin: Dietrich Reimer Verlag, 1997, 23 9 + 323 + 275 pp. - H.J.M. Claessen, Jan Rensel, Home in the islands; Housing and social change in the Pacific. Honolulu: University of Hawai’i Press, 1997, vii + 264 pp., Margaret Rodman (eds. - Peter van Eeuwijk, Norbert Kohnen, Traditionelle Medizin auf den Philippinen; Angstbewältigung und kognition bei Krankheiten. Stuttgart: Steiner, 1992, 396 pp. [Beiträge zur Südasienforschung 154.] - C.D. Grijns, William A. Smalley, Linguistic diversity and national unity; Language ecology in Thailand. Chicago: University of Chicago Press, 1994, xv + 436 pp. - Nico Kaptein, Ulrike Freitag, Hadhrami traders, scholars, and statesmen in the Indian Ocean, 1750s-1960s. Leiden: Brill, 1997, x + 392 pp., William G. Clarence-Smith (eds. - Elsbeth Locher-Scholten, Raden Ajeng Kartini, On feminism and nationalism; Kartini’s letters to Stella Zeehandelar 1899-1903, translated and with an introduction by Joost Coté. Clayton, Victoria: Monash Asia Instiute, Monash University, xxiii + 129 pp. - Alison Murray, L. Manderson, Sites of desire, economies of pleasure: Sexualities in Asia and the Pacific. Chicago: University of Chicago Press, 1997, xii + 367 pp., M. Jolly (eds. - Chris Penders, Harry A. Poeze, Politiek-Politioneele Overzichten van Nederlandsch-Indië, Deel IV, 1935-1941. Leiden: KITLV Uitgeverij, 1994, xciv + 485 pp. - Kathryn Robinson, Henk Schulte Nordholt, The spell of power; A history of Balinese politics 1650-1940. Leiden: The KITLV Press, 1996, ix + 389 pp. [VKI 170.] - Eric Tagliacozzo, Carl A. Trocki, Gangsters, democracy, and the state in Southeast Asia. Ithaca, N.Y.: Cornell University Southeast Asia Program, 1998, 94 pp. [Cornell University Southeast Asia Program

  19. The role of the humanities in the Bologna idea of a university: learning from the American model?

    Directory of Open Access Journals (Sweden)

    Jesper Eckhardt Larsen

    2006-01-01

    Full Text Available The Humboldtian idea of a university has, for better or for worse, served as a blueprint for the past two centuries of university development in large parts of Europe. It entails the idea of a unity between research and personal cultivation (Bildung that indeed has its shortcomings. Since the advent of a strong specialization and theorization the humanities have largely abandoned the more educational function, Bildung in its educational and ethical sense.The American liberal arts college- and university tradition on the other hand,particularly at the bachelor level, has traditionally separated the purely educational readings of a humanities ‘canon’ from the more scholarly pursuits of the humanities. Recent debates on the humanities show these differences across the Atlantic. While the highly specialized humanities in Europe have great problems proving their relevance in a modern society and job-market, the humanities in America are mostly discussed in terms of their educational accountability. Could the Bologna process be an occasionfor the European bachelor to be remodelled along the lines of the American liberal arts model? Could the humanities prove their relevance to non specialists in European higher education?La idea humboldtiana de la universidad ha sido, para bien o para mal, una referencia para el desarrollo universitario en una gran parte de Europa durante los dos siglos pasados. Implica un concepto de unión entre investigación y formación (Bildung que, efectivamente, tiene sus defectos. Desde la llegada de una fuerte especialización y teorización, las Humanidades han abandonado, en su mayor medida, la función educacional, Bildung en su sentido ético. Por otra parte, la tradición universitaria de las Artes Liberales americanas, particularmente a nivel de Licenciatura, ha diferenciado la lectura puramente educacional del «canon», del meramente académico. Debates recientes han mostrado la existencia de esta diferenciaci

  20. The effects of single dose TBI on hepatic and renal function in non-human primates and patients

    International Nuclear Information System (INIS)

    Broerse, J.J.; Bakker, B.; Davelaar, J.; Leer, J.W.H.; Niemer-Tucker, M.M.B.; Noordijk, E.M.

    1996-01-01

    Total body irradiation (TBI) and bone marrow transplantation (BMT) are common procedures in the treatment of severe combined immune deficiency syndromes, leukemia, non-Hodgkin lymphoma and other hematological disorders. Improved results following TBI and BMT have increased the number of patients in long term follow up. Late detrimental effects of TBI have been investigated in non-human primates and patients with emphasis on vital organs like liver and kidney. The response of monkeys to radiation is not significantly different from that in man. Long term effects of TBI could be studied by keeping 84 monkeys of different ages under continuous observation for a period up to 25 years. Effects on hepatic and renal function were demonstrated using serological and histological parameters. The values of the liver function parameters such as alkaline phosphatase and gamma glutamyl transferase in the irradiated group are significantly increased after TBI. Also the parameters of kidney dysfunction, e.g., Ht and urea show a significant change in the irradiated old aged cohort with respect to the controls. Between 1967 and 1993, 336 bone marrow transplantations were performed at the University Hospital Leiden. The present Study was restricted to those patients who survived at least 18 months after transplantation. This retrospective analysis consequently amounts to 120 patients. The monkey data indicated subclinical organ damage for postirradiation intervals exceeding 15 years. However, up to the present time, the human data do not support these findings since the follow up time is still restricted to a median survival of 4,5 years. Detrimental effects in liver and kidney function at a later stage can not be excluded yet, and careful examinations of the patients remain indicated

  1. African Studies Abstracts Online : number 53, 2016

    NARCIS (Netherlands)

    African Studies Centre Leiden (ASCL),

    2016-01-01

    ASA Online provides a quarterly overview of journal articles and edited works on Africa in the field of the social sciences and the humanities available in the ASC library. Issue 53 (2016). African Studies Centre, Leiden.

  2. African Studies Abstracts Online: number 53, 2016

    OpenAIRE

    African Studies Centre Leiden (ASCL)

    2016-01-01

    ASA Online provides a quarterly overview of journal articles and edited works on Africa in the field of the social sciences and the humanities available in the ASC library. Issue 53 (2016). African Studies Centre, Leiden.

  3. Extent of Implementing Accreditation and Quality Assurance Standards in Azal University of Human Development from the Faculty Members’ Perspective

    Directory of Open Access Journals (Sweden)

    Mohammed Zain Saleh ALSadi

    2017-10-01

    Full Text Available The research aimed to find out how far accreditation and quality assurance standards in Azal University for human development are implemented from the perspective of faculty members. To achieve this objective, to the researchers adopted descriptive analytical approach techniques. The research population was all the teaching staff at the university; and the sample consisted of (94 faculty members, (48.45 % of the total number of the population. A questionnaire was designed to collect data relevant to the testing of the research objectives. The questionnaire consisted of two parts: the first included the personal data, while the second part included the standards of accreditation and quality assurance. The study revealed the following results: The mean of implementing standards as a whole was (3.44, the standard deviation (0.76, and the extent of the using the standards was (high. There were no significant differences between the research participants’ responses about the extent of using the standards due to the variables (gender – Qualification – college type – years of teaching experience. In light of the results of the study, a set of recommendations were presented, including the need to provide the necessary requirements for implementing accreditation and quality assurance standards, whether material, human or financial resources, and creating a positive conducive learning environment to be suitable and ready for a complete implementation of quality standards. One of the main suggestions made by the research was to conduct a similar study on government and private universities and community colleges in Yemen. Keywords: Quality Assurance and accreditation; Azal University of Human Development.

  4. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2003-10-01

    Full Text Available -Monika Arnez, Keith Foulcher ,Clearing a space; Postcolonial readings of modern Indonesian literature. Leiden: KITlV Press, 2002, 381 pp. [Verhandelingen 202.], Tony Day (eds -R.H. Barnes, Thomas Reuter, The house of our ancestors; Precedence and dualism in highland Balinese society. Leiden: KITLV Press, 2002, viii + 359 pp. [Verhandelingen 198.] -Freek Colombijn, Adriaan Bedner, Administrative courts in Indonesia; A socio-legal study. The Hague: Kluwer law international, 2001, xiv + 300 pp. [The London-Leiden series on law, administration and development 6.] -Manuelle Franck, Peter J.M. Nas, The Indonesian town revisited. Singapore: Institute of Southeast Asian studies, 2002, vi + 428 pp. [Southeast Asian dynamics.] -Hans Hägerdal, Ernst van Veen, Decay or defeat? An inquiry into the Portuguese decline in Asia 1580-1645. Leiden: Research school of Asian, African and Amerindian studies, 2000, iv + 306 pp. [Studies on overseas history, 1.] -Rens Heringa, Genevieve Duggan, Ikats of Savu; Women weaving history in eastern Indonesia. Bangkok: White Lotus, 2001, xiii + 151 pp. [Studies in the material culture of Southeast Asia 1.] -August den Hollander, Kees Groeneboer, Een vorst onder de taalgeleerden; Herman Nuebronner van der Tuuk; Afgevaardigde voor Indië van het Nederlandsch Bijbelgenootschap 1847-1873; Een bronnenpublicatie. Leiden: KITlV Uitgeverij, 2002, 965 pp. -Edwin Jurriëns, William Atkins, The politics of Southeast Asia's new media. London: RoutledgeCurzon, 2002, xii + 235 pp. -Victor T. King, Poline Bala, Changing border and identities in the Kelabit highlands; Anthropological reflections on growing up in a Kelabit village near an international frontier. Kota Samarahan, Sarawak: Unit Penerbitan Universiti Malayasia Sarawak, Institute of East Asian studies, 2002, xiv + 142 pp. [Dayak studies contemporary society series 1.] -Han Knapen, Bernard Sellato, Innermost Borneo; Studies in Dayak cultures. Singapore: Singapore University Press

  5. The emotional impact of genetic testing and aspects of counseling prior to prescription of oral contraceptives.

    Science.gov (United States)

    Gartner, Verena; Weber, Michael; Eichinger, Sabine

    2008-11-01

    Oral contraceptives increase the thrombotic risk in women with factor V Leiden. Emotional aspects of genetic testing prior to the prescription of oral contraceptives (OC), aspects of counseling and referral patterns are widely unknown. Two hundred forty-seven women with and 132 women without factor V Leiden were interviewed by questionnaire. One hundred sixty-one women (65%) with factor V Leiden and 63 (48%) with wild-type factor V responded. One hundred seventy-one women (76%) reported being emotionally disturbed by genetic testing. Eighty percent of women with factor V Leiden and 16% of women with wild-type factor V were discouraged from OC use. Three percent of women with factor V Leiden were encouraged to take OC. Forty-one percent of women with factor V Leiden used at least one hormone contraceptive method after diagnosis. Only 46 women (29%) with factor V Leiden were counseled about the relevance of the mutation in case of pregnancy. Testing for factor V Leiden has considerable emotional impact. Recommendations after testing are not consistently driven by the test result.

  6. Balancing the principles: why the universality of human rights is not the Trojan horse of moral imperialism.

    Science.gov (United States)

    Semplici, Stefano

    2013-11-01

    The new dilemmas and responsibilities which arise in bioethics both because of the unprecedented pace of scientific development and of growing moral pluralism are more and more difficult to grapple with. At the 'global' level, the call for the universal nature at least of some fundamental moral values and principles is often being contended as a testament of arrogance, if not directly as a new kind of subtler imperialism. The human rights framework itself, which provided the basis for the most relevant international declarations and documents, is not exempt from the charge. However, the refusal of a top-down conception of the universal as a sort of product for exportation should not be confused with a relativistic landscape, where all the cows can be indifferently black or white. This contribution aims at outlining an approach, which reconciles universalism as enshrined in founding human rights declarations with respect for cultural diversity. In order to do so, two conceptual frameworks are discussed: the 'tool-kit' model and the morals/ethics difference. The example of the right to quality health care confirms the argument that striking a balance between cherishing pluralism and defending some fundamental rights and obligations does not amount to an assertion of moral imperialism.

  7. Dr C. Beets (1916-1995) and the 'Rijksmuseum van Geologie en Mineralogie'

    NARCIS (Netherlands)

    Winkler Prins, C.F.

    1996-01-01

    Dr Cornelis Beets, internationally renowned specialist of Indonesian Cainozoic molluscs, died on the 28th of July 1995. Born April 25, 1916, he read geology at Leiden University and obtained his PhD in 1941 on a geological study of the Turin Hills (Italy). When working on his PhD, he had already

  8. Revision of the Sapotaceae of the Malaysian area in a wider sense. XIII. Chrysophyllum L

    NARCIS (Netherlands)

    Vink, W.

    1958-01-01

    In the present study only those species of the genus Chrysophyllum have been incorporated which are found in the area covered by the Flora Malesiana, as well as those of Australia and New Caledonia. We express our most sincere thanks to the Curators of the State University at Leiden for allowing a

  9. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964),

  10. The Historical Significance of the Universal Declaration.

    Science.gov (United States)

    Eide, Asbjorn

    1998-01-01

    Explains the historical significance of the Universal Declaration of Human Rights. Focuses on the initiative for the Declaration and its elaboration, the precursors to modern human rights, the foundation of the Declaration, the rights contained in the Universal Declaration, three modes of human rights analysis, and global governance and human…

  11. Development of a Medical Humanities Program at Dalhousie University Faculty of Medicine, Nova Scotia, Canada, 1992-2003.

    Science.gov (United States)

    Murray, Jock

    2003-10-01

    The Medical Humanities Program at Dalhousie University Faculty of Medicine in Nova Scotia, Canada, was initiated in 1992 to incorporate the medical humanities into the learning and experiences of medical students. The goal of the program was to gain acceptance as an integral part of the medical school. The program assumed a broad concept of the medical humanities that includes medical history, literature, music, art, multiculturalism, philosophy, epistemology, theology, anthropology, professionalism, history of alternative therapies, writing, storytelling, health law, international medicine, and ethics. Phase I of the program has provided the same elective and research opportunities in the medical humanities that are available to the students in clinical and basic sciences, and has encouraged and legitimized the involvement of the humanities in the life and learning of the medical student through a wide array of programs and activities. Phase II will focus on further incorporation of the humanities into the curriculum. Phase III will be the development of a graduate program in medical humanities to train more faculty who will incorporate the humanities into their teaching and into the development of education programs.

  12. Vulnerability, diversity and scarcity: on universal rights.

    Science.gov (United States)

    Turner, Bryan Stanley; Dumas, Alex

    2013-11-01

    This article makes a contribution to the on-going debates about universalism and cultural relativism from the perspective of sociology. We argue that bioethics has a universal range because it relates to three shared human characteristics,--human vulnerability, institutional precariousness and scarcity of resources. These three components of our argument provide support for a related notion of 'weak foundationalism' that emphasizes the universality and interrelatedness of human experience, rather than their cultural differences. After presenting a theoretical position on vulnerability and human rights, we draw on recent criticism of this approach in order to paint a more nuanced picture. We conclude that the dichotomy between universalism and cultural relativism has some conceptual merit, but it also has obvious limitations when we consider the political economy of health and its impact on social inequality.

  13. Proposing a Universal Framework for Resilience: Optimizing Risk and Combating Human Vulnerabilities

    Science.gov (United States)

    Sarkar, Arunima

    2017-04-01

    strengthen and optimize the decision making skill and platform for a better sustainable society. The resilience framework provides a cross-sector and multi-level analysis to tackle the vulnerabilities which can be caused to essential utilities like power, water, transport and various machineries that are essential for human sustainability. The direction of resilience framework focuses on prevention of damage and disruption of disaster, mitigate the loss caused to human society and provide the best response for disaster resilience. Thus, the basic pillars which are important for the implementation of resilience is proper governance framework and transparency which takes into account various cost and risk analysis. Thus a common and universal framework for resilience is the main requirement for mass accessibility. The aim of resilience framework focuses on universal adaptability, coherence and validation. A mixed method analysis has been undertaken in this research paper which focuses on the following issues: • Legal, Institutional and community framework for integrating resilience framework of global north and global south. • Spatial as well as statistical analysis to structuralize disaster risk and resilient framework for disaster management. • Early warning system and emergency response in a comparative scale to analyse the various models of risk and resilience framework implemented in USA, China, Nepal and India for proposing an integrated resilience strategy.

  14. Is thrombophilia a major risk factor for deep vein thrombosis of the lower extremities among Lebanese patients?

    Directory of Open Access Journals (Sweden)

    R Kreidy

    2009-07-01

    Full Text Available R Kreidy1, N Irani-Hakime21Department of Vascular Surgery, 2Department of Laboratory Medicine, Saint George Hospital, University Medical Center, University of Balamand, Beirut, LebanonAim: Factor V Leiden (R506Q mutation is the most commonly observed inherited genetic abnormality related to vein thrombosis. Lebanon has one of the highest frequencies of this mutation in the world with a prevalence of 14.4% in the general population. The aim of this study is to define risk factors including inherited genetic abnormalities among Lebanese patients with lower extremity deep vein thrombosis. We report the clinical outcome of patients with thrombophilia.Methods: From January 1998 to January 2008, 162 patients (61 males and 101 females were diagnosed with lower extremity deep vein thrombosis. Mean age was 61 years (range: 21 to 95 years.Results: The most frequent risk factors for vein thrombosis were surgery, advanced age, obesity, and cancer. Twenty-five patients had thrombophilia, 16 patients had factor V Leiden (R506Q mutation, and seven patients had MTHFR C677T mutation. Ninety-two percent of patients screened for thrombophilia were positive. Screening was requested in young patients (16, patients with recurrent (11, spontaneous (8, and extensive (5 venous thrombosis, familial history (5, pregnancy (4, estroprogestative treatment (3, and air travel (1. Nine patients had one, 11 patients had two, and five had three of these conditions. Follow-up (6 to 120 months of these 25 patients treated with antivitamin K did not reveal recurrences or complications related to venous thromboembolism.Conclusion: Factor V Leiden mutation followed by MTHFR mutation are the most commonly observed genetic abnormalities in these series. Defining risk factors and screening for thrombophilia when indicated reduce recurrence rate and complications. Recommendations for thrombophilia screening will be proposed.Keywords: venous thrombosis, risk factors, genetics, factor V

  15. Measuring human betterment through avoidable mortality: a case for universal health care in the USA.

    Science.gov (United States)

    Hisnanick, J J; Coddington, D A

    1995-10-01

    The USA system of health care has begun a monumental change that will affect everyone, irrespective of their socioeconomic status, professional status or pre-existing health insurance status. Whatever type of plan is finally implemented through the legislative process, there will need to be a way to evaluate its success (or failure). One way to evaluate the plan's effectiveness is through its impact on human betterment as viewed by a reduction in 'avoidable mortality' for those most in need of health care; the poor and uninsured. For one USA minority population, universal health care has improved human betterment by reducing avoidable mortality, even in the face of a severe burden of poverty.

  16. STUDI KOMPARATIF ANTARA UNIVERSAL DECLARATION OF HUMAN RIGHTS 1948 DAN THE CAIRO DECLARATION ON HUMAN RIGHTS IN ISLAM 1990

    Directory of Open Access Journals (Sweden)

    Sunaryo Sunaryo

    2014-03-01

    Full Text Available Diskusi Hak Asasi Manusia (HAM merupakan salah satu topik yang tetap aktual dan mengglobal di samping masalah demokrasi dan lingkungan hidup. Manusia sebagai makhluk Tuhan dan makhluk sosial memiliki hak-hak asasi yang mesti dihormati dan dilindungi oleh siapapun. Di dalam Universal Declaration of Human Rights 1948 (UDHR dan di dalam The Cairo Declaration on Human Rights In Islam 1990 (CD, berbagai macam hak-hak asasi dimaksud telah diatur secara general dan komprehensif. Meskipun demikian, di antara kedua deklarasi tersebut di samping mempunyai persamaan juga memiliki perbedaan. Perbedaan-perbedaan tersebut antara lain tentang asal atau sumber dari masing-masing deklarasi yang tidak sama, hak atas kebebasan beragama dan hak untuk menikah, serta hak atas kewarganegaraan seseorang. Sementara itu ada juga ketentuan-ketentuan yang diatur di dalam CD tetapi tidak diatur dalam UDHR atau sebaliknya, seperti tentang riba (Pasal 14 CD tidak diatur di dalam UDHR, sebaliknya ketentuan tentang kebebasan berserikat dan berkumpul (Pasal 20 UDHR tidak diatur di dalam CD

  17. Patients’ perceptions of conservative treatment for a small abdominal aortic aneurysm

    Directory of Open Access Journals (Sweden)

    Tomee SM

    2018-01-01

    Full Text Available Stephanie M Tomee,1 Winifred A Gebhardt,2 Jean-Paul PM de Vries,3 Victoria C Hamelinck,1 Jaap F Hamming,1 Jan HN Lindeman1 1Department of Surgery, Leiden University Medical Center, Leiden, 2Health, Medical and Neuropsychology Unit, Institute of Psychology, Leiden University, Leiden, 3Department of Vascular Surgery, St Antonius Hospital, Nieuwegein, Leiden, the Netherlands Background: An abdominal aortic aneurysm (AAA is a progressive, generally symptomless disease that could ultimately result in a fatal rupture. Current guidelines advise conservative follow-up, and preventive surgical repair once the risk of rupture outweighs the cost of repair (55 mm in men. In developed countries, the majority of patients are diagnosed with AAAs less than 55 mm, and so enter a period of conservative surveillance. An important question is how patients perceive and cope with risk of rupture, AAA diagnosis and treatment, and presented AAA information. The goal of this study was to gain insight into patients’ perceptions of conservative treatment for a small AAA to increase patient satisfaction.Methods: We conducted semistructured in-depth interviews and used questionnaires measuring health-related quality of life (RAND 36-Item Health Survey 1.0, illness-perceptions (Illness Perception Questionnaire – Revised, and anxiety and depression (Hospital Anxiety and Depression Scale. Interviews were audio recorded and transcript contents were analyzed based on grounded theory. Mean scores of the questionnaires were compared to (population reference groups.Results: This study included ten male patients under surveillance for a small AAA from two hospitals in the Netherlands. Patients expressed no fear for AAA rupture, and also reported low levels of anxiety and depression in both the interviews and the Hospital Anxiety and Depression Scale. The presence of an AAA did not affect their social life or emotional well-being. The reported poorer physical health on RAND 36

  18. Contesting Border/Frontier Studies in China and Beyond: The Prospects and Pitfalls of Zomia as a Metaphor

    Directory of Open Access Journals (Sweden)

    Jinba Tenzin

    2017-09-01

    Full Text Available Megan Bryson. Goddess on the Frontier: Religion, Ethnicity, and Gender in Southwest China. Stanford, CA: Stanford University Press, 2016. 264 pp. $60 (cloth. Xiaofei Kang and Donald S. Sutton. Contesting the Yellow Dragon: Ethnicity, Religion, and the State in the Sino-Tibetan Borderland. Leiden: Brill, 2016. 494 pp. $202 (cloth/e-book.

  19. The Study of Scientific Outputs Status of Faculty Members of Humanities, Art and Social Sciences Faculties of State Universities of Iran during 2000-2008

    Directory of Open Access Journals (Sweden)

    Fatemeh Jafari

    2012-07-01

    Full Text Available This research investigated scientific outputs status of faculty members of Humanities, Art and Social Sciences faculties of state universities of Iran that indexed in A&HCI and SSCI during 2000 to 2008. Descriptive and analytical method was used to conduct this research. Findings showed that Tehran University with 38/73% and then Shiraz University with 15.65% had the greatest value of scientific outputs, while in other universities the status of scientific outputs was not satisfying. Article with 76.42% was the most published format and then meeting abstract, book review, proceeding paper are next in rank . 65.65% of scientific outputs were collective and 34.34% individual. Scientific outputs development process in universities during the investigated period was ascending. Scientific outputs of Humanities, Art and Social Sciences faculties of state universities were published in167 titles and through these 135 titles (80.83% were indexed in Journal Citation Reports and among these the impact factor of 74 journals (54.81% range from 0 to 1 and the other 61 (45.18% journals’ impact factors value more than one.

  20. Increased expression of endothelial antigen PAL-E in human diabetic retinopathy correlates with microvascular leakage

    NARCIS (Netherlands)

    Schlingemann, R. O.; Hofman, P.; Vrensen, G. F.; Blaauwgeers, H. G.

    1999-01-01

    AIMS/HYPOTHESIS: The Pathologische Anatomie Leiden-Endothelium (PAL-E) antigen is a marker for loss of the blood-brain barrier function in brain tumours. It is endothelium specific and is associated with the endothelial plasmalemmal vesicles (caveolae) involved in transcellular transport. To test

  1. Study of an investigation on factors influencing human resources productivity in Shiraz University of Medical Sciences

    Directory of Open Access Journals (Sweden)

    Zahra Ghasemi

    2016-01-01

    Full Text Available Introduction: Human resources development is one of the most important components of any organization and detecting important factors influencing human resources management plays an essential role in the success of the firms. In this study, we investigated different factors influencing human resources productivity of Shiraz University of Medical Sciences staff. Method: The present research was a cross-sectional study. Sample size was calculated 208 individuals. To access information about the human resource productivity, a valid and reliable questionnaire was used. The data were analyzed using SPSS software. Pearson correlation was used for statistical analysis of the data (p=0.05. Results:The results showed that there was a statistically significant relationship (p-value<0.001 between human resources productivity and factors affecting the productivity of human resources (motivational factors, leadership style, creativity and innovation, general and applied education, and competitive spirit. Motivational factors (r =0.89 and general education (r =0.65 had the most and the least effects on human resources productivity. Conclusion: Considering the fact that motivational factors were the most effective factors on human resource productivity, we recommend that managers should care more than before about this factor; also, in order to motivate the employees, they should consider the staff’s individual differences.

  2. Knowledge, perception and attitude towards human papillomavirus among pre-university students in Malaysia.

    Science.gov (United States)

    Kwang, Ng Beng; Yee, Choy Mun; Shan, Lim Pei; Teik, Chew Kah; Chandralega, Kampan Nirmala; Abdul Kadir, Abdul Karim

    2014-01-01

    To evaluate the knowledge, perception and attitudes towards human papilloma virus (HPV) among pre-university students in Malaysia. In this cross sectional study, between November 2013 to March 2014, in a public university, a convenient sampling method was used. A total of 716 respondents were recruited and interviewed with a set of standard questionnaires for assessment of knowledge, perception and attitudes towards HPV and predictor variables associated with level of knowledge. Almost half (48.9%) of the respondents scored less than 5 and were categorised as having poor knowledge. Three hundred and twelve (43.6%) respondents had moderate knowledge and only 54 (7.5%) respondents exhibited good knowledge with the score of 11 and above. Only 142 (20%) students perceived themselves to be vulnerable to HPV infection though 560 (78.2%) students thought that HPV infection is a serious disease. Perceived benefits and desire to be vaccinated were significantly associated with gender (p=0.000) and knowledge of HPV vaccine and cervical cancer (p=0.000). The level of knowledge regarding HPV among the pre-university students was low. However, student intention for vaccination increased with increasing level of knowledge. Thus, efforts to improve knowledge and awareness should be prioritised to increase uptake of the HPV vaccination programme and hence reduce morbidity and mortality from consequences of HPV infection, including cervical carcinoma.

  3. Malaysia's Human Rights Performance: Assessment of its First Session of Universal Periodic Review in the United Nations Human Rights Council

    Directory of Open Access Journals (Sweden)

    Ying Hooi Khoo

    2014-05-01

    Full Text Available Since its inception, the Universal Periodic Review (UPR has been subjected to a substantial amount of criticism. The mechanism began functioning in 2008, however there have been little made known about the roles and functions of the UPR. This article explicitly examines the first UPR process of Malaysia in 2009, in order to illustrate how the mechanism operates in practice by highlighting the engagement of Malaysia government with the stakeholders, the follow-up process and the main issues concerned. This article argues that in spite of the excellent diplomacy skills that portrayed by the Malaysian government in the UPR session, the human rights situation in the country has not been improved much. This paper seeks to determine how effective the UPR has been at encouraging human rights reforms nationally by analyzing and assessing the implementation actions of Malaysian government in response to their accepted UPR recommendations.

  4. Personal news

    NARCIS (Netherlands)

    NN,

    1980-01-01

    Dr. M.M.J. van Balgooy and his companions on the Celebes Expedition, Dr. E. Hennipman, Mr. G.J. de Joncheere and Dr. E.F. de Vogel left Leiden on 5 April 1979, visited the SING and BO-Herbaria on the way. In Celebes visit was paid to Hasanudin University at Ujung Pandang (olim Makassar), in Bali to

  5. Academic Specialization and Contemporary University Humanities Centers

    Science.gov (United States)

    Brownley, Martine W.

    2012-01-01

    Given the academic specialization endemic today in humanities disciplines, some of the most important work of humanities centers has become promoting education about the humanities in general. After charting the rise of humanities centers in the US, three characteristics of centers that enable their advancement of larger concerns of the humanities…

  6. Assessment of Morphological Variations and its Specific Location on the Surface of Adult Human Liver in Ethiopian Cadavers University of Gondar, Bahir Dar University, Addis Ababa University, St. Paulos Medical School and Hawassa University, Ethiopia

    Directory of Open Access Journals (Sweden)

    Tsegaye Mehare

    2017-10-01

    Full Text Available Background: Liver is the second largest organ next to skin and located in right hypochondrium, epigastrium and may extend to left hypochondrium in upper abdominal cavity. It accounts 2% to 3% of total body weight of individual. Land marking for interpreting different diagnostic image and localizing lesions in the liver is commonly done by major fissures. Sound knowledge about different morphological variations which are found on the surface of liver is mandatory to have safe surgical outcome. Segments of liver were extensively researched but there are only few studies dealt with the surface variation of the liver. Therefore, this study aims to assess morphological variations and its specific location on the surface of adult human liver in Ethiopian cadaver. Methodology: Institutional based cross sectional descriptive study design was conducted in 33 formalin fixed Ethiopian cadaveric livers in the Anatomy department of University of Gondar, Bahir Dar University, Addis Ababa University, St. Paulos Medical School and Hawassa University. Results: 45.45% of the liver was normal but 54.55% showed one or more variations. Additional fissures and very small left lobe with deep costal impressions were seen 27.27% and 21.21% cases respectively. Pons hepatis connecting left lobe with quadrate lobe and very deep renal impression with corset constriction were noted in 9.09% cases each. Additional lobes and absence of quadrate lobes were found in 6.06% cases each. Conclusion and Recommendation: Morphological variations on the liver surface were accessory fissure, very small left lobe with deep costal impressions, pons hepatis, shape variation and absence of quadrate lobe. The most common one among the variations was accessory fissure on the visceral and diaphragmatic surface.

  7. (Re)Discovering University Autonomy

    DEFF Research Database (Denmark)

    This book challenges traditional approach to university autonomy which is based on four pillars: organisational, financial, human resource, and academic. The main thesis is that a fuller understanding of university autonomy can only be obtained through a more holistic view of the complex inter-re...

  8. What Unites Us All: Establishing Special Education Teacher Education Universals

    Science.gov (United States)

    Darling, Sharon M.; Dukes, Charles; Hall, Kalynn

    2016-01-01

    The theoretical base that supports human universals served as a model for proposing special education teacher education universals. The human universals model is explained and put forth as a basis for identifying special education teacher education universals. Twenty-four English language journals from different countries representing four…

  9. A Christian Critique of the University.

    Science.gov (United States)

    Malik, Charles Habib

    Views on the place and power of the university, the church's role in the university, and the sciences and humanities are presented. The secularization of western universities raises fundamental criticisms from the Christian point of view that the university atmosphere is not congenial to Christian spiritual values, and that higher education…

  10. Assessing the quality of VA Human Research Protection Programs: VA vs. affiliated University Institutional Review Board.

    Science.gov (United States)

    Tsan, Min-Fu; Nguyen, Yen; Brooks, Robert

    2013-04-01

    We compared the Human Research Protection Program (HRPP) quality indicator data of the Department of Veterans Affairs (VA) facilities using their own VA institutional review boards (IRBs) with those using affiliated university IRBs. From a total of 25 performance metrics, 13 did not demonstrate statistically significant differences, while 12 reached statistically significance differences. Among the 12 with statistically significant differences, facilities using their own VA IRBs performed better on four of the metrics, while facilities using affiliate IRBs performed better on eight. However, the absolute difference was small (0.2-2.7%) in all instances, suggesting that they were of no practical significance. We conclude that it is acceptable for facilities to use their own VA IRBs or affiliated university IRBs as their IRBs of record.

  11. Universal mortality law and immortality

    Science.gov (United States)

    Azbel', Mark Ya.

    2004-10-01

    Well-protected human and laboratory animal populations with abundant resources are evolutionarily unprecedented. Physical approach, which takes advantage of their extensively quantified mortality, establishes that its dominant fraction yields the exact law, which is universal for all animals from yeast to humans. Singularities of the law demonstrate new kinds of stepwise adaptation. The law proves that universal mortality is an evolutionary by-product, which at any given age is reversible, independent of previous life history, and disposable. Life expectancy may be extended, arguably to immortality, by minor biological amendments in the animals. Indeed, in nematodes with a small number of perturbed genes and tissues it increased 6-fold (to 430 years in human terms), with no apparent loss in health and vitality. The law relates universal mortality to specific processes in cells and their genetic regulation.

  12. The right of public access to legal information : A proposal for its universal recognition as a human right

    NARCIS (Netherlands)

    Mitee, Leesi Ebenezer

    2017-01-01

    Abstract: This Article examines the desirability of the universal recognition of the right of public access to legal information as a human right and therefore as part of a legal framework for improving national and global access to legal information. It discusses the right of public access to legal

  13. Rhodes University

    African Journals Online (AJOL)

    Samridhi Sharma

    2013-10-29

    Oct 29, 2013 ... been taken may improve the reception, by the target audience, of the intended communication. This may ... alcohol marketing. Similarly .... of the intended users (Rhodes University support staff ..... Digital Human Modeling and.

  14. Astronomy through the ages the story of the human attempt to understand the universe

    CERN Document Server

    Wilson, Sir Robert

    2003-01-01

    From an historical perspective, this text presents an entirely non- mathematical introduction to astronomy from the first endeavours of the ancients to the current developments in research enabled by cutting edge technological advances. Free of mathematics and complex graphs, the book nevertheless explains deep concepts of space and time, of relativity and quantum mechanics, and of origin and nature of the universe. It conveys not only the intrinsic fascination of the subject, but also the human side and the scientific method as practised by Kepler, defined and elucidated by Galileo, and then demonstrated by Newton.

  15. Role of International Study Experiences in the Personal and Professional Development of University Lecturers in the Humanities and Social Sciences Fields in Thailand

    Science.gov (United States)

    Kaowiwattanakul, Sukanya

    2016-01-01

    This study investigates the role of international experience on personal and professional development of university academic staff in the Humanities and Social Sciences fields in Thailand. The participants were 23 lecturers from nine universities in Thailand. A semi-structured face-to-face interviewing method was employed. The findings reveal that…

  16. Are (Should) Human Rights (Be) Universal?

    Science.gov (United States)

    Howard, Rhoda E.

    1998-01-01

    Believes that the purpose of human rights is to change many culturally ingrained habits and customs that violate the dignity of the individual. Expounds the differences between cultural relativism and cultural absolutism. States that "weak" cultural relativism is sometimes an appropriate response to human-rights violations. (CMK)

  17. Lower blood pressure and apathy coincide in older persons with poorer functional ability: the Discontinuation of Antihypertensive Treatment in Elderly People (DANTE) Study Leiden.

    Science.gov (United States)

    Moonen, Justine E F; Bertens, Anne Suzanne; Foster-Dingley, Jessica C; Smit, Roelof A J; van der Grond, Jeroen; de Craen, Anton J M; de Ruijter, Wouter; van der Mast, Roos C

    2015-01-01

    To examine the association between blood pressure (BP) measures and symptoms of apathy and depression in older adults with various levels of functional ability. Cross-sectional study using baseline data from the Discontinuation of Antihypertensive Treatment in Elderly people (DANTE) Study Leiden. Primary care setting, the Netherlands. Community-dwelling individuals aged 75 and older (N = 430). Systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured during home visits. Symptoms of apathy and depression were assessed using the Apathy Scale and the Geriatric Depression Scale (GDS-15), respectively. Stratified linear regression was performed in participants with better and worse functional ability according to the median of the Groningen Activity Restriction Scale. In participants with lower functional ability, each 10-mmHg lower SBP, DBP, and MAP was associated with higher Apathy Scale scores (0.63, 0.92, and 0.94 points, respectively, all P < .005) but not with GDS-15 scores. In participants with higher functional ability, BP measures were not associated with Apathy Scale or GDS-15 scores. In older participants with poorer functional ability, lower BP was associated with more symptoms of apathy but not depression. © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.

  18. Effects of the Use of Electronic Human Resource Management (EHRM Within Human Resource Management (HRM Functions at Universities

    Directory of Open Access Journals (Sweden)

    Chux Gervase Iwu

    2016-09-01

    Full Text Available This study set out to examine the effect of e-hrm systems in assisting human resource practitioners to execute their duties and responsibilities. In comparison to developed economies of the world, information technology adoption in sub-Saharan Africa has not been without certain glitches. Some of the factors that are responsible for these include poor need identification, sustainable funding, and insufficient skills. Besides these factors, there is also the issue of change management and users sticking to what they already know. Although, the above factors seem negative, there is strong evidence that information systems such as electronic human resource management present benefits to an organization. To achieve this, a dual research approach was utilized. Literature assisted immensely in both the development of the conceptual framework upon which the study hinged as well as in the development of the questionnaire items. The study also made use of an interview checklist to guide the participants. The findings reveal a mix of responses that indicate that while there are gains in adopting e-hrm systems, it is wiser to consider supporting resources as well as articulate the needs of the university better before any investment is made.

  19. Human Rights/Human Needs.

    Science.gov (United States)

    Canning, Cynthia

    1978-01-01

    The faculty of Holy Names High School developed an interdisciplinary human rights program with school-wide activities focusing on three selected themes: the United Nations Universal Declaration of Human Rights, in conjunction with Human Rights Week; Food; and Women. This article outlines major program activities. (SJL)

  20. Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy

    Directory of Open Access Journals (Sweden)

    de Groot S

    2017-06-01

    Full Text Available Stefanie de Groot,1 Hans Gelderblom,1 Marta Fiocco,2,3 Judith VMG Bovée,4 Jacobus JM van der Hoeven,1 Hanno Pijl,5 Judith R Kroep1 1Department of Medical Oncology, 2Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 3Mathematical Department, Leiden University, 4Department of Pathology, 5Department of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands Background: Activation of the insulin-like growth factor 1 (IGF-1 pathway is involved in cell growth and proliferation and is associated with tumorigenesis, tumor progression, and therapy resistance in solid tumors. We examined whether variability in serum levels of IGF-1, IGF-2, and IGF-binding protein 3 (IGF-BP3 can predict event-free survival (EFS and overall survival (OS in Ewing sarcoma patients treated with chemotherapy.Patients and methods: Serum levels of IGF-1, IGF-2, and IGF-BP3 of 22 patients with localized or metastasized Ewing sarcoma treated with six cycles of vincristine/ifosfamide/doxorubicin/etoposide (VIDE chemotherapy were recorded. Baseline levels were compared with presixth cycle levels using paired t-tests and were tested for associations with EFS and OS. Continuous variables were dichotomized according to the Contal and O’Quigley procedure. Survival analyses were performed using Cox regression analysis.Results: High baseline IGF-1 and IGF-BP3 serum levels were associated with EFS (hazard ratio [HR] 0.075, 95% confidence interval [CI] 0.009–0.602 and HR 0.090, 95% CI 0.011–0.712, respectively in univariate and multivariate analyses (HR 0.063, 95% CI 0.007–0.590 and HR 0.057, 95% CI 0.005–0.585, respectively. OS was improved, but this was not statistically significant. IGF-BP3 and IGF-2 serum levels increased during treatment with VIDE chemotherapy (P=0.055 and P=0.023, respectively.Conclusion: High circulating serum levels of IGF-1 and IGF-BP3 and the molar ratio of IGF-1:IGF-BP3 serum levels were associated

  1. Phonology without universal grammar.

    Science.gov (United States)

    Archangeli, Diana; Pulleyblank, Douglas

    2015-01-01

    The question of identifying the properties of language that are specific human linguistic abilities, i.e., Universal Grammar, lies at the center of linguistic research. This paper argues for a largely Emergent Grammar in phonology, taking as the starting point that memory, categorization, attention to frequency, and the creation of symbolic systems are all nonlinguistic characteristics of the human mind. The articulation patterns of American English rhotics illustrate categorization and systems; the distribution of vowels in Bantu vowel harmony uses frequencies of particular sequences to argue against Universal Grammar and in favor of Emergent Grammar; prefix allomorphy in Esimbi illustrates the Emergent symbolic system integrating phonological and morphological generalizations. The Esimbi case has been treated as an example of phonological opacity in a Universal Grammar account; the Emergent analysis resolves the pattern without opacity concerns.

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    Niels Mulder

    1997-04-01

    Full Text Available - Peter Boomgaard, Robert L. Winzeler, Latah in Southeast Asia; The history and ethnography of a culture-bound syndrome. Cambridge: Cambridge University Press, 1995, xvi + 172 pp. [Publications of the Society for Psychological Anthropology 7.] - Ad Borsboom, H.C. Coombs, Aboriginal autonomy; Issues and strategies. Cambridge: Cambridge University Press, 1995, xvi + 251 pp. - Ad Borsboom, Daniel de Coppet, Cosmos and society in Oceania. Oxford: Berg, 1995, 416 pp. [Explorations in Anthropology Series]., André Iteanu (eds. - Raymond L. Bryant, P. Boomgaard, Forests and forestry 1823-1941. Amsterdam: Royal Tropical Institute, 184 pp. [Changing Economy in Indonesia vol. 16]., R. de Bakker (eds. - David Henley, Jan M. Pluvier, Historical atlas of South-east Asia. Leiden/New York/Köln: Brill, 1995, 83 + 64 pp. [Handbuch der Orientalistik, Dritter Abteilung (Südostasien, Achter Band]. - Victor T. King, Nico Schulte Nordholt, Social science in Southeast Asia; From particularism to universalism. Amsterdam: VU University Press (for the Centre for Asian Studies Amsterdam, 1995, 165 pp. [Comparative Asian Studies 17]., Leontine Visser (eds. - Han Knapen, Bernard Sellato, Nomads of the Borneo rainforest; The economics, politics, and ideology of settling down. Translated by Stephanie Morgan. Honolulu: University of Hawaii Press, 1994, xxiii + 280 pp. - R.Z. Leirissa, David E.F. Henley, Nationalism and regionalism in a colonial context; Minahasa in the Dutch East Indies. Leiden: KITLV Press, 1996, xii + 186 pp. [Verhandelingen 168]. - K. Loven, Kees Epskamp, On printed matter and beyond; Media, orality and literacy. The Hague: Centre for the Study of Education in Developing Countries (CESO, 1995, 136 pp. [CESO Paperback 23]. - Niels Mulder, Andrée Feillard, Islam et armée dans l’Indonésie contemporaine; Les pionniers de la tradition, Paris: Éditions l’Harmattan, 1995, 379 pp. [Association Archipel, Cahier d’Archipel 28]. - Tessel Pollmann, Cees

  3. Book Reviews

    Directory of Open Access Journals (Sweden)

    Peter Pels

    1995-04-01

    Full Text Available - Freek Colombijn, Hisao Furukawa, Coastal wetlands of Indonesia; Environment, subsistence and exploitation. Translated by Peter Hawkes. Kyoto: Kyoto University Press, 1994, vii + 219 pp., tables, figures, index. - C. van Dijk, Virginia Matheson Hooker, Culture and society in New Order Indonesia, Kuala Lumpur: Oxford University Press, 1993, xxiii + 302 pp. - M.R. Fernando, Frans van Baardewijk, The cultivation system, Java 1834-1880, Changing Economy in Indonesia 14. Amsterdam: Royal Tropical Institute, 1993, 327 pp. - Bernice D. de Jong Boers, Jacqueline Vel, The Uma-economy; Indigenous economics and development work in Lawonda, Sumba (Eastern Indonesia. PhD thesis Landbouwuniversiteit Wageningen, 1994, viii + 283 pp. Maps, tables, photographs, glossary. - Marijke J. Klokke, Lydia Kieven, Arjunas Askese; Ihre Darstellung im altjavanischen Arjunawiwaha und auf ausgewählten ostjavanischen Reliefs. Kölner Südostasien Studien Bd. 2. Bonn: Holos, 1994, 154 pp. - Marijke J. Klokke, Edi Sedyawati, Ganesa statuary of the Kadiri and Sinhasari periods; A study of art history. Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde 160. Leiden: KITLV Press 1994. - Gijs Koster, Annabel Teh Gallop, The legacy of the Malay letter - Warisan warkah Melayu. With an essay by E. Ulrich Kratz. London: British Library for the National Archives of Malaysia, 1994, 240 pp. - Stephen Markel, Marijke J. Klokke, Ancient Indonesian Sculpture, Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde 165. Leiden: KITLV Press 1994, vii + 210 pp., Pauline Lunsingh Scheurleer (eds. - Anke Niehof, Ingrid Rudie, Visible women in East coast Malay society; On the reproduction of gender in ceremonial, school and market. Oslo: Scandinavian University Press, 1994, xi + 337 pp. - Peter Pels, Nicholas Thomas, Colonialism’s culture; Anthropology, travel and government. Cambridge: Polity Press, 1994, xi + 238 pp. - Peter Pels, Nicholas B

  4. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

    DEFF Research Database (Denmark)

    Deelen, Joris; Beekman, Marian; Uh, Hae-Won

    2011-01-01

    By studying the loci which contribute to human longevity, we aim to identify mechanisms that contribute to healthy aging. To identify such loci, we performed a genome-wide association study (GWAS) comparing 403 unrelated nonagenarians from long-living families included in the Leiden Longevity Stu...

  5. (Re)Discovering University Autonomy

    DEFF Research Database (Denmark)

    This book challenges traditional approach to university autonomy which is based on four pillars: organisational, financial, human resource, and academic. The main thesis is that a fuller understanding of university autonomy can only be obtained through a more holistic view of the complex inter......-relationships between stakeholders and policies which can reinforce and equally pull in opposite directions. The holistic view is expressed in a model of institutional university autonomy that brings together the traditional basic four pillars of autonomy, and five interfaces: government–university; university......–university staff; academic staff–students; university–business; and university–internationalisation. This model is explored through international case studies that give new insights and reinforce our understanding that the issues relating to institutional university autonomy are complex, interactive and genuinely...

  6. Slavery, religion, and abolition in Suriname

    Directory of Open Access Journals (Sweden)

    Johannes Postma

    1997-07-01

    Full Text Available [First paragraph] "Om werk van jullie te hebben": Plantageleven in Suriname, 1730-1750. RUDI OTTO BEELDSNIJDER. Utrecht: Vakgroep Culturele Antropologie - Bronnen voor de Studie van Afro-Surinaamse Samenlevingen, 1994. xii + 351 pp. (Paper NLG 35.00 Surinaams contrast: Roofbouw en overleven in een Caraibische plantagekolonie 1750-1863. ALEX VAN STIPRIAAN. Leiden: KITLV Press, 1995. xiii + 494 pp. (Paper NLG 60.00 Strijders voor het Lam: Leven en werk van Herrnhutter broeders en zusters in Suriname, 1735-1900. MARIA LENDERS. Leiden: KITLV Press, 1996. xii + 451 pp. (Paper NLG 65.00 Fifty Years Later: Antislavery, Capitalism and Modernity in the Dutch Orbit. GERT OOSTINDIE (ed.. Leiden: KITLV Press, 1995; Pittsburgh: University of Pittsburgh Press, 1996. viii + 272 pp. (Paper NLG 45.00, US$ 22.50, Cloth US$ 45.00 The publication of the books under review is evidence of a growing scholarly interest in the history of Dutch activities in the Atlantic. Three of them are doctoral dissertations on Suriname history; the fourth contains the published proceedings of a conference held in 1993 that focused on the abolition of slavery in the Dutch colonies. Three were published by the Royal Institute of Linguistics and Anthropology (KITLV, which exhibits an increasing interest in publishing scholarly books about Dutch overseas history.

  7. Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics

    Directory of Open Access Journals (Sweden)

    Ratcliffe P

    2017-03-01

    Full Text Available Peter Ratcliffe,1,2 Peppi Koivunen,3 Johanna Myllyharju,3 Jiannis Ragoussis,4 Judith VMG Bovée,5 Ines Batinic-Haberle,6 Claire Vinatier,7 Valérie Trichet,8 Florence Robriquet,9 Lisa Oliver,9 Betty Gardie9,10 1Target Discovery Institute, University of Oxford, 2The Francis Crick Institute, London, UK; 3Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland; 4McGill University and Genome Quebec Innovation Centre, McGill University, Montreal, Canada; 5Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands; 6Department of Radiation Oncology, Duke University School of Medicine, Durham, NC, USA; 7INSERM UMR 1229, Regenerative Medicine and Skeleton-RMeS, Team STEP, University of Nantes, UFR Odontology, 8UMR 1238 INSERM, Université de Nantes, Faculté de Médecine, 9CRCINA, INSERM, Université de Nantes, Nantes, 10Ecole Pratique des Hautes Etudes, PSL Research University, Paris, France Abstract: The “Hypoxia Nantes 2016” organized its second conference dedicated to the field of hypoxia research. This conference focused on “the role of hypoxia under physiological conditions as well as in cancer” and took place in Nantes, France, in October 6–7, 2016. The main objective of this conference was to bring together a large group of scientists from different spheres of hypoxia. Recent advances were presented and discussed around different topics: genomics, physiology, musculoskeletal, stem cells, microenvironment and cancer, and oxidative stress. This review summarizes the major highlights of the meeting. Keywords: hypoxia, genomics, lipid metabolism, musculoskeletal, cancer, oxidative stress 

  8. Understanding University Technology Transfer

    Science.gov (United States)

    Association of American Universities, 2011

    2011-01-01

    Federal government agencies provide about $33 billion a year to universities to conduct scientific research. That continuing investment expands human knowledge and helps educate the next generation of science and technology leaders. New discoveries from university research also form the basis for many new products and processes that benefit the…

  9. Talent Management for Universities

    Science.gov (United States)

    Bradley, Andrew P.

    2016-01-01

    This paper explores human resource management practices in the university sector with a specific focus on talent pools and talent management more generally. The paper defines talent management in the context of the university sector and then explores its interdependence with organisational strategy, the metrics used to measure academic performance…

  10. Malignant astrocytoma following radiotherapy for craniopharyngioma

    Energy Technology Data Exchange (ETDEWEB)

    Maat-Schieman, M.L.C.; Bots, G.T.A.M.; Thomeer, T.W.M.; Vielvoye, G.J. (Rijksuniversiteit Leiden (Netherlands). Hospital)

    1985-05-01

    The case report describes a boy with a malignant astrocytoma in the mid-line of the cerebellum 14 years after X-ray therapy for craniopharyngioma. In Leiden University Hospital this is the first case of a suspected radiation-induced brain tumour in 66 patients treated for cranial lesions by radiotherapy between 1969 and 1979 who have survived more than 5 years.

  11. Malignant astrocytoma following radiotherapy for craniopharyngioma

    International Nuclear Information System (INIS)

    Maat-Schieman, M.L.C.; Bots, G.T.A.M.; Thomeer, T.W.M.; Vielvoye, G.J.

    1985-01-01

    The case report describes a boy with a malignant astrocytoma in the mid-line of the cerebellum 14 years after X-ray therapy for craniopharyngioma. In Leiden University Hospital this is the first case of a suspected radiation-induced brain tumour in 66 patients treated for cranial lesions by radiotherapy between 1969 and 1979 who have survived more than 5 years. (author)

  12. C. Walker-Said and J. D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp

    DEFF Research Database (Denmark)

    Whelan, Glen

    2017-01-01

    Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp.......Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp....

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Chanatip Kesavadhana

    2000-01-01

    Full Text Available - A.S. Baer, Philip Houghton, People of the Great Ocean; Aspects of human biology of the early Pacific. Cambridge: Cambridge University Press, 1996, x + 292 pp. - Greg Bankoff, Vicente L. Rafael, Figures of criminality in Indonesia, the Philippines, and colonial Vietnam. Ithaca, NY: Cornell University Southeast Asis Program, 1999, 258 pp. - Harold Brookfield, Donald Denoon, The Cambridge history of the Pacific Islanders. Cambridge: Cambridge University Press, 1997, xvi + 518 pp., Stewart Firth, Jocelyn Linnekin (eds. - Cynthia Chou, Shoma Munshi, Clifford Sather, The Bajau Laut; Adaptation, history, and fate in a maritime fishing society of south-eastern Sabah. Kuala Lumpur: Oxford University Press, 1997, xviii + 359 pp. - Cynthia Chou, Shoma Munshi, Krishna Sen, Gender and power in affluent Asia. London: Routledge, 1998, xiii + 323 pp., Maila Stivens (eds. - Freek Colombijn, Arne Kalland, Environmental movements in Asia. Richmond, Surrey: Curzon, 1998, xiii + 296 pp. [Nordic Institute of Asian Studies, Man and Nature in Asia Series 4.], Gerard Persoon (eds. - Kirsten W. Endres, Phan Huy Chu, Hai trinh chi luoc; Récit sommaire d’un voyage en mer (1833; Un émissaire Vietnamien à Batavia. Paris: EHESS, 1994, viii + 228 pp. [Cahier d’Archipel 25.] - Aone van Engelenhoven, Veronica Du Feu, Rapanui. London: Routledge, 1996, xv + 217 pp. [Routledge Descriptive Grammars.] - Fukui Hayao, Peter Boomgard, Paper landscapes; Explorations in the environmental history of Indonesia, 1997, vi + 424 pp. Leiden: KITLV Press. [Verhandelingen 178.], Freek Colombijn, David Henley (eds. - Volker Heeschen, J. Miedema, Texts from the oral tradition in the south-western Bird’s Head Peninsula of Irian Jaya; Teminabuan and hinterland. Leiden: DSALCUL, Jakarta: ISIR, 1995, vi + 98 pp. [Irian Jaya Source Materials 14.] - Volker Heeschen, J. Miedema, Texts from the oral tradition in the southern Bird’s Head Peninsula of Irian Jaya; Inanwatan-Berau, Arandai

  14. Book Reviews

    Directory of Open Access Journals (Sweden)

    Ann Kumar

    1999-10-01

    Full Text Available - Chris Ballard, Jeroen A. Overweel, Topics relating to Netherlands New Guinea in Ternate Residency memoranda of transfer and other assorted documents. Leiden: DSALCUL, Jakarta: IRIS, 1995, x + 146 pp. [Irian Jaya Source Materials 13.] - Timothy P. Barnard, Daniel Perret, Sejarah Johor-Riau-Lingga sehingga 1914; Sebuah esei bibliografi. Kuala Lumpur: Kementerian Kebudayaan, Kesenian dan Pelancongan Malaysia/École Francaise d’Extrême Orient, 1998, 460 pp. - Peter Boomgaard, Om Prakash, European commercial enterprise in pre-colonial India. Cambridge: Cambridge University Press, 1998, xviii + 377 pp. [The New Cambridge History of India II-5.] - U.T. Bosma, Oliver Kortendick, Drei Schwestern und ihre Kinder; Rekonstruktion von Familiengeschichte und Identitätstransmission bei Indischen Nerlanders mit Hilfe computerunterstützter Inhaltsanalyse. Canterbury: Centre for Social Anthropology and Computing, University of Kent at Canterbury, 1996, viii + 218 pp. [Centre for Social Anthropology and Computing Monograph 12.] - Freek Colombijn, Thomas Psota, Waldgeister und Reisseelen; Die Revitalisierung von Ritualen zur Erhaltung der komplementären Produktion in SüdwestSumatra. Berlin: Reimer, 1996, 203 + 15 pp. [Berner Sumatraforschungen.] - Christine Dobbin, Ann Maxwell Hill, Merchants and migrants; Ethnicity and trade among Yunannese Chinese in Southeast Asia. New Haven: Yale University Southeast Asia Studies, 1998, vii + 178 pp. [Yale Southeast Asia Studies Monograph 47.] - Aone van Engelenhoven, Peter Bellwood, The Austronesians; Historical and comparative perspectives. Canberra: Department of Anthropology, Research School of Pacific and Asian Studies, Australian National University, 1995, viii + 359 pp., James J. Fox, Darrell Tryon (eds. - Aone van Engelenhoven, Wyn D. Laidig, Descriptive studies of languages in Maluku, Part II. Jakarta: Badan Penyelenggara Seri NUSA and Universitas Katolik Indonesia Atma Jaya, 1995, xii + 112 pp. [NUSA

  15. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability.

    Directory of Open Access Journals (Sweden)

    Paul W Burridge

    2011-04-01

    Full Text Available The production of cardiomyocytes from human induced pluripotent stem cells (hiPSC holds great promise for patient-specific cardiotoxicity drug testing, disease modeling, and cardiac regeneration. However, existing protocols for the differentiation of hiPSC to the cardiac lineage are inefficient and highly variable. We describe a highly efficient system for differentiation of human embryonic stem cells (hESC and hiPSC to the cardiac lineage. This system eliminated the variability in cardiac differentiation capacity of a variety of human pluripotent stem cells (hPSC, including hiPSC generated from CD34(+ cord blood using non-viral, non-integrating methods.We systematically and rigorously optimized >45 experimental variables to develop a universal cardiac differentiation system that produced contracting human embryoid bodies (hEB with an improved efficiency of 94.7±2.4% in an accelerated nine days from four hESC and seven hiPSC lines tested, including hiPSC derived from neonatal CD34(+ cord blood and adult fibroblasts using non-integrating episomal plasmids. This cost-effective differentiation method employed forced aggregation hEB formation in a chemically defined medium, along with staged exposure to physiological (5% oxygen, and optimized concentrations of mesodermal morphogens BMP4 and FGF2, polyvinyl alcohol, serum, and insulin. The contracting hEB derived using these methods were composed of high percentages (64-89% of cardiac troponin I(+ cells that displayed ultrastructural properties of functional cardiomyocytes and uniform electrophysiological profiles responsive to cardioactive drugs.This efficient and cost-effective universal system for cardiac differentiation of hiPSC allows a potentially unlimited production of functional cardiomyocytes suitable for application to hPSC-based drug development, cardiac disease modeling, and the future generation of clinically-safe nonviral human cardiac cells for regenerative medicine.

  16. Teaching nanoscience across scientific and geographical borders - A European Master programme in nanoscience and nanotechnology

    International Nuclear Information System (INIS)

    Chesneau, A; Schwille, P; Groeseneken, G; Heremans, P; Rep, D; Rudquist, P; Wendin, G; Sluijter, B

    2008-01-01

    Within the Erasmus Mundus Master (EMM) Programme, five European Universities (KU Leuven, Belgium, Chalmers University of Technology, Sweden, Delft University of Technology and Leiden University, the Netherlands, and the University of Dresden, Germany) have joined forces to offer a unique master programme in Nanoscience and Nanotechnology, 'EMM-nano', at the cutting edge of state-of-the-art research. The students design and build their individual area of specialisation within nanophysics, nanotechnology, biophysics, biotechnology through their choice of trajectory between the partners. We discuss some of the challenges related to the crossdisciplinary nature of the field, educational activities in cleanrooms, and issues related to the integration of teaching programmes across the borders within Europe

  17. Paul Ehrenfest, Niels Bohr, and Albert Einstein: Colleagues and Friends

    Science.gov (United States)

    Klein, Martin J.

    2010-09-01

    In May 1918 Paul Ehrenfest received a monograph from Niels Bohr in which Bohr had used Ehrenfest's adiabatic principle as an essential assumption for understanding atomic structure. Ehrenfest responded by inviting Bohr, whom he had never met, to give a talk at a meeting in Leiden in late April 1919, which Bohr accepted; he lived with Ehrenfest, his mathematician wife Tatyana, and their young family for two weeks. Albert Einstein was unable to attend this meeting, but in October 1919 he visited his old friend Ehrenfest and his family in Leiden, where Ehrenfest told him how much he had enjoyed and profited from Bohr's visit. Einstein first met Bohr when Bohr gave a lecture in Berlin at the end of April 1920, and the two immediately proclaimed unbounded admiration for each other as physicists and as human beings. Ehrenfest hoped that he and they would meet at the Third Solvay Conference in Brussels in early April 1921, but his hope was unfulfilled. Einstein, the only physicist from Germany who was invited to it in this bitter postwar atmosphere, decided instead to accompany Chaim Weizmann on a trip to the United States to help raise money for the new Hebrew University in Jerusalem. Bohr became so overworked with the planning and construction of his new Institute for Theoretical Physics in Copenhagen that he could only draft the first part of his Solvay report and ask Ehrenfest to present it, which Ehrenfest agreed to do following the presentation of his own report. After recovering his strength, Bohr invited Ehrenfest to give a lecture in Copenhagen that fall, and Ehrenfest, battling his deep-seated self-doubts, spent three weeks in Copenhagen in December 1921 accompanied by his daughter Tanya and her future husband, the two Ehrenfests staying with the Bohrs in their apartment in Bohr's new Institute for Theoretical Physics. Immediately after leaving Copenhagen, Ehrenfest wrote to Einstein, telling him once again that Bohr was a prodigious physicist, and again

  18. New mutations and an updated database for the patched-1 (PTCH1) gene.

    Science.gov (United States)

    Reinders, Marie G; van Hout, Antonius F; Cosgun, Betûl; Paulussen, Aimée D; Leter, Edward M; Steijlen, Peter M; Mosterd, Klara; van Geel, Michel; Gille, Johan J

    2018-05-01

    Basal cell nevus syndrome (BCNS) is an autosomal dominant disorder characterized by multiple basal cell carcinomas (BCCs), maxillary keratocysts, and cerebral calcifications. BCNS most commonly is caused by a germline mutation in the patched-1 (PTCH1) gene. PTCH1 mutations are also described in patients with holoprosencephaly. We have established a locus-specific database for the PTCH1 gene using the Leiden Open Variation Database (LOVD). We included 117 new PTCH1 variations, in addition to 331 previously published unique PTCH1 mutations. These new mutations were found in 141 patients who had a positive PTCH1 mutation analysis in either the VU University Medical Centre (VUMC) or Maastricht University Medical Centre (MUMC) between 1995 and 2015. The database contains 331 previously published unique PTCH1 mutations and 117 new PTCH1 variations. We have established a locus-specific database for the PTCH1 gene using the Leiden Open Variation Database (LOVD). The database provides an open collection for both clinicians and researchers and is accessible online at http://www.lovd.nl/PTCH1. © 2018 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc.

  19. Assessing university students' sexual risk behaviors as predictors of human papillomavirus (HPV) vaccine uptake behavior.

    Science.gov (United States)

    Rohde, Rebecca L; Adjei Boakye, Eric; Christopher, Kara M; Geneus, Christian J; Walker, Ronald J; Varvares, Mark A; Osazuwa-Peters, Nosayaba

    2018-05-09

    There exists a significant gap in vaccine coverage of the human papillomavirus (HPV) among college-aged students. This study assessed sexual risk-taking behavior among university students and analyzed predictors of HPV vaccine initiation and completion in this population. Data (n = 746) were from an anonymous online, cross-sectional survey distributed to university students, between the ages of 19-26 years, at a private Midwestern university. Both chi-square and multivariable logistics regression models estimated the association between sociodemographic characteristics and sexual risk factors (including number of vaginal sexual partners, number of oral sexual partners, initiation of oral sex, and initiation of vaginal sex), with HPV vaccine initiation and completion. A significant number of participants (40%) had not received a single dose of the HPV vaccine series. Of those who initiated the series, more than half (51%) did not achieve completion. Additionally, a greater number of participants have had multiple (4 or more) oral sexual partners than vaginal sexual partners (25.7% vs. 20.3%). After adjusting for covariates, it was found that sexual risk factors were not significantly associated with HPV vaccine initiation or completion. HPV vaccine initiation and completion rates are suboptimal among university students. High levels of sexual-risk taking behaviors associated with HPV infection persist, yet are not significant predictors of HPV vaccine behaviors in this age group. To increase uptake among 18-26-year-old students, future public health interventions should focus on HPV vaccine education and uptake across the entire population, irrespective of sexual risk profile. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. For the Problem of Knowledge of the Universe

    Science.gov (United States)

    Kalanov, Temur Z.

    2003-04-01

    incorrect if they contain the assumption of existence of the bound of the Universe (i.e. if concepts of singular state of the Universe, of expending or compressing of the Universe, of stability or instability of the Universe underlie the theories). (2) The principle of movement of the Universe: the movement of the Universe is represented by birth and extermination of objects and, consequently, change of structure of the Universe as a system. In particular, it means that there exist copies of objects. (In fact, the principle of identity of quantum particles of the same kind (for example, electrons) is a form of manifestation (consequence) of the principle of birth and extermination of objects). (3) The principle of movement of the Universe is a form of manifestation of the principle of development of the Universe (Nature). (4) The principle of development of the Universe (Nature) is a form of manifestation of the principle of existence of Unitary (i.e. of God). (5) The principle of existence of Unitary (God): Unitary (God) exists as the dialectical unity, identity of the opposites the real (material) and non real (non material) aspects of Unitary. (6) The principle of existence of Unitary (God) represents principal point of a new dialectical gnosiology (i.e. theory of knowledge). (7) Dialectical unity, identity of human practice and of human non practice (i.e. of human ethics based on comprehension of existence of God) is the criterion human truth. (8) The criterion of human truth determines a true way of knowledge of the Nature (Universe). (9) A bound of human knowledge and of human development is determined by development principle. (10) The existence of the bound of human development means existence of the bound only between Mankind and non Mankind (i.e. Supreme Intellect). Hence, the end of evolution of Mankind means transition, transformation, transmutation, dissolution of Mankind into Supreme Intellect. The comprehension of existence of Supreme Intellect around us will

  1. On longevity and the aging process : a magnetic resonance imaging study of the brain

    NARCIS (Netherlands)

    Altmann-Schneider, Irmhild

    2015-01-01

    The aim of this thesis was to investigate the radiological phenotype of the human brain in familial longevity with regard to brain structure. This study was performed as part of the Leiden Longevity Study – a study population consisting of offspring of long-lived Dutch people who are genetically

  2. Astronomy in the Digital Universe

    Science.gov (United States)

    Haisch, Bernard M.; Lindblom, J.; Terzian, Y.

    2006-12-01

    The Digital Universe is an Internet project whose mission is to provide free, accurate, unbiased information covering all aspects of human knowledge, and to inspire humans to learn, make use of, and expand this knowledge. It is planned to be a decades long effort, inspired by the Encyclopedia Galactica concept popularized by Carl Sagan, and is being developed by the non-profit Digital Universe Foundation. A worldwide network of experts is responsible for selecting content featured within the Digital Universe. The first publicly available content is the Encyclopedia of Earth, a Boston University project headed by Prof. Cutler Cleveland, which will be part of the Earth Portal. The second major content area will be an analogous Encyclopedia of the Cosmos to be part of the Cosmos Portal. It is anticipated that this will evolve into a major resource for astronomy education. Authors and topic editors are now being recruited for the Encyclopedia of the Cosmos.

  3. In Search of Cultural Universals: Translation Universals. Case Studies

    Directory of Open Access Journals (Sweden)

    Gabriela DIMA

    2014-12-01

    Full Text Available Knowledge of the world is disclosed under various shapes, among which language is the best representative. Specific to humans, it renders feelings and thoughts concerning different communication contexts where words become dynamic primitives endowed with meanings, which recreate themes and reconfigure space and time as universal coordinates. The main objective of the paper is to provide a tentative analysis of the way in which translation universals are manifest in translating proverbs and sayings in the short novels Popa Tanda (Pope Tanda and Moara cu Noroc (The Lucky Mill by Ioan Slavici.

  4. Las plantas vasculares de la Península Ibérica en la obra de Clusio: envíos de semillas de Sevilla a Leiden

    Directory of Open Access Journals (Sweden)

    Menéndez de Luarca, Luis Ramón-Laca

    1997-12-01

    Full Text Available Before 1575 Carolus Clusius visited Spain and Portugal, in what can be considered the first extensive botanical collection trip for the Iberian Peninsula. He published in 1576 Rariorum aliquot stirpium per Hispanias observatarum historia, mainly based on materials collected during that expedition. The content of this book was later merged with additional information to créate a more comprehensive work dealing with the whole European flora, Rariorum plantarum historiae, published in 1601. An important element in the generation of this second book was the collaboration of Simón de Tovar, from Seville, who contributed with shipments of seeds and bulbs to Clusius. Thanks to Tovar, the number of plants recorded in Rar. stirp. hispan, hist, was increased with some remarkable examples in Rar. pl. hist. It is particularly interesting to note that at that moment American plants were a great novelty and Seville was the gate for the introduction of most of them, i.e. Sprekelia formosissima (L. Herbert [• Amaryllis formosissima L.] or Psidium guajava L. A reconstruction of Clusius itinerary based on the collection localities is given in this paper. A discussion of the correspondence between both botanists, including a critical list of the plants sent to Leiden by Tovar is presented.Carolus Clusius, o sencillamente Clusio, visitó España y Portugal antes de 1575, en lo que puede considerarse la primera herborización sistemática de la Península Ibérica. En 1576 fue publicada en Amberes la obra Rariorum aliquot stirpium per Hispanias observatarum historia, basada fundamentalmente en el material colectado durante este viaje. Esta obra fue refundida posteriormente con información adicional en Rariorum plantarían historiae, publicada en 1601, que trataba de abarcar el conjunto de la flora europea. Un elemento importante en la génesis de esta segunda obra fue la colaboración del sevillano Simón de Tovar, quien contribuyó con envíos de semillas

  5. Question of Drug Workers under the Prism Theory of Axel Honneth recognition . Human Right to Work and his pretension of Universal Validity

    OpenAIRE

    Maria Cecília Máximo Teodoro; Sabrina Colares Nogueira

    2016-01-01

    Relate the theme regarding the Theory of Recognition Axel Honnet, the human right to work as a human right to claim to universal validity, from the perspective of the Declaration of Fundamental Principles and Rights at Work ILO, for purposes of setting parameters and recognition of social (re) integration of chemical class dependent workers is the main goal of this article. We will analyze the theoretical framework in which the pursuit of human dignity at work is the goal of the state to whic...

  6. Néo-conservatisme contre Universalisme Neo-conservatism vs Universalism

    Directory of Open Access Journals (Sweden)

    Frank Romano

    2009-10-01

    Full Text Available This study will first set forth the principles underpinning universalism and neo-conservatism, followed by the re-launching of the polemic which pits neoconservatives against universalism, the former seeking to privilege the American Empire. The setting up and the support of international structures has become necessary for a true protection of human rights and true cooperation in the face of war and other conflicts. This requires the enhancement of a new concept, that of unification of the human race by unification of legal principles and by their universal application. The conflicts between nations give rise to the necessity for universal structures, such as an international tribunal capable of pursuing international anticompetitive practices, as well as those accused of genocide and crimes against humanity. Thus, a universalistic approach within a legal framework becomes fundamental for justice, even for the survival of humanity. However, American interventionist and neoconservative policy flies in the face of a universal movement. It advances rather the notion of the American Empire, which attempts to impose itself with impunity throughout today’s world. Moreover and extraordinarily, the Bush Administration succeeded in bringing together two opponents, the neoconservative and Fundamentalist Christian movements, which, together, block the progression of the universalistic movement towards a more balanced and evolved human race. As such, does the neoconservative movement, which encourages the development of this Empire, push the world into a downward anti-universal spiral? Does it even threaten to jeopardize our very survival? So-called universalism is the proposed answer to this threat. The antithesis to universalism is a political movement created in the United States: neoconservatism.

  7. Pomp and Circumstance: University Presidents and the Role of Human Capital in Determining Who Leads U.S. Research Institutions

    Science.gov (United States)

    Singell, Larry D., Jr.; Tang, Hui-Hsuan

    2013-01-01

    While there is wide agreement that leaders matter, little is known regarding the role that human capital plays in determining who becomes one. We exploit unique attributes of the higher education industry to examine if training and academic ability affect the placement of university presidents within the research hierarchy of U.S. institutions.…

  8. Knowledge of Saudi female university students regarding cervical cancer and acceptance of the human papilloma virus vaccine

    OpenAIRE

    Al-Shaikh, Ghadeer K.; Almussaed, Eman M.; Fayed, Amel A.; Khan, Farida H.; Syed, Sadiqa B.; Al-Tamimi, Tahani N.; Elmorshedy, Hala N.

    2014-01-01

    Objectives: To assess the level of knowledge regarding cervical cancer and the acceptance of the human papilloma virus (HPV) vaccine among Saudi female students in health colleges. Methods: This cross-sectional study of a convenient sample encompassed 1400 students in Health Colleges at Princess Nora Bint Abdul Rahman University, Riyadh, Saudi Arabia was conducted between December 2013 and February 2014. A self-administrated questionnaire was distributed to all participants. Data collected in...

  9. Human Rights in the Humanities

    Science.gov (United States)

    Harpham, Geoffrey

    2012-01-01

    Human rights are rapidly entering the academic curriculum, with programs appearing all over the country--including at Duke, Harvard, Northeastern, and Stanford Universities; the Massachusetts Institute of Technology; the Universities of Chicago, of Connecticut, of California at Berkeley, and of Minnesota; and Trinity College. Most of these…

  10. Question of Drug Workers under the Prism Theory of Axel Honneth recognition . Human Right to Work and his pretension of Universal Validity

    Directory of Open Access Journals (Sweden)

    Maria Cecília Máximo Teodoro

    2016-06-01

    Full Text Available Relate the theme regarding the Theory of Recognition Axel Honnet, the human right to work as a human right to claim to universal validity, from the perspective of the Declaration of Fundamental Principles and Rights at Work ILO, for purposes of setting parameters and recognition of social (re integration of chemical class dependent workers is the main goal of this article. We will analyze the theoretical framework in which the pursuit of human dignity at work is the goal of the state to which we treat below the dignity of man as a right whose claim to universal validity is based on the recognition of the theory of Axel Honneth . That said, we analyze the possible dignity of man at work in a global context from the recognition of new rights, especially with regard to the category of workers who occupy the social portion of chemical-dependent, whose participation in the social process is prevented, creating a category of workers socially excluded, which is intended to overcome.

  11. Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study.

    Science.gov (United States)

    van Bemmel, Thomas; Delgado, Victoria; Bax, Jeroen J; Gussekloo, Jacobijn; Blauw, Gerard J; Westendorp, Rudi G; Holman, Eduard R

    2010-04-01

    Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of daily living in community dwelling nonagenarians. Nested within the Leiden 85-plus study, a population based follow-up study of the oldest old, a sample of 81 nonagenarians was recruited. The left ventricular (LV) dimensions, function and the presence and severity of heart valvular disease were evaluated by echocardiography. Significant valvular heart disease included any mitral or aortic stenosis severity, moderate or severe mitral regurgitation, moderate or severe aortic regurgitation and moderate or severe tricuspid regurgitation. Activities of daily living were assessed using the Groningen Activity Restriction Scale (GARS). LV cavity diameters (end-diastolic diameter 47 +/- 8 mm, end-systolic diameter 30 +/- 8 mm) and systolic LV function (LV ejection fraction 66 +/- 13%) were within normal for the majority of the participants. Significant valvular disease was present in 57 (70%) individuals, with mitral regurgitation and aortic regurgitation as the most frequent valve diseases (49% and 28% respectively). The GARS score between individuals with and without significant valvular heart disease was similar (36.2 +/- 9.2 vs. 34.4 +/- 13.2, p = 0.5). Nonagenarian, outpatient individuals have a high prevalence of significant valvular heart disease. However, no relation was observed between the presence of significant valvular heart disease and the ability to perform activities of daily living.

  12. Plasminogen activator inhibitor-1 4G/5G polymorphism, factor V Leiden, prothrombin mutations and the risk of VTE recurrence.

    Science.gov (United States)

    Sundquist, Kristina; Wang, Xiao; Svensson, Peter J; Sundquist, Jan; Hedelius, Anna; Larsson Lönn, Sara; Zöller, Bengt; Memon, Ashfaque A

    2015-11-25

    Plasminogen-activator inhibitor (PAI)-1 is an important inhibitor of the plasminogen/plasmin system. PAI-1 levels are influenced by the 4G/5G polymorphism in the PAI-1 promoter. We investigated the relationship between the PAI-1 polymorphism and VTE recurrence, and its possible modification by factor V Leiden (FVL) and prothrombin (PTM) mutations. Patients (n=1,069) from the Malmö Thrombophilia Study were followed from discontinuation of anticoagulant treatment until diagnosis of VTE recurrence or the end of the study (maximum follow-up 9.8 years). One hundred twenty-seven patients (11.9 %) had VTE recurrence. PAI-1 was genotyped by TaqMan PCR. Cox regression analysis adjusted for age, sex and acquired risk factors of VTE showed no evidence of an association between PAI-1 genotype and risk of VTE recurrence in the study population as a whole. However, by including an interaction term in the analysis we showed that FVL but not PTM modified the effect of PAI-1 genotype: patients with the 4G allele plus FVL had a higher risk of VTE recurrence [hazard ratio (HR) =2.3, 95 % confidence interval (CI) =1.5-3.3] compared to patients with the 4G allele but no FVL (reference group) or FVL irrespective of PAI-1 genotype (HR=1.8, 95 % CI=1.3-2.5). Compared to reference group, 5G allele irrespective of FVL was associated with lower risk of VTE recurrence only when compared with 4G allele together with FVL. In conclusion, FVL has a modifying effect on PAI-1 polymorphism in relation to risk of VTE recurrence. The role of PAI-1 polymorphism as a risk factor of recurrent VTE may be FVL dependent.

  13. Kant's universal law formula revisited

    NARCIS (Netherlands)

    Nyholm, S.

    2015-01-01

    Kantians are increasingly deserting the universal law formula in favor of the humanity formula. The former, they argue, is open to various decisive objections; the two are not equivalent; and it is only by appealing to the human- ity formula that Kant can reliably generate substantive implications

  14. Human resources department in crisis: A case of a university in South Africa

    Directory of Open Access Journals (Sweden)

    Bethuel Sibongiseni Ngcamu

    2014-11-01

    Full Text Available Human Resources (HR departments in previously disadvantaged higher education institutions (HEI in South Africa have contributed to the crisis that has led them to be governed by appointed Administrators assigned by the Ministry of Higher Education and Training. The malfunctioning of HR departments persists even in the post-Administrator’s era, with a prevalence of personal, interpersonal and operational challenges. This study aimed at interrogating challenges faced by the HR Department of the university concerned post the appointed Administrator era and its negative effects. This study adopted a qualitative research approach whereby in-depth interviews were conducted with a sample of 10 HR Department staff members. Focus group discussions were also carried out with 20 academic and non-academic university leaders. Further data was also collected through ethnographic observation and secondary data was also used. The non-probability purposive sampling was used for qualitative analysis and NVivo was used for organizing and analyzing data gleaned from the in-depth interviews. The study findings consistently revealed unclear roles and responsibilities, outmoded recruitment and selection processes and poor interpersonal relations amongst the HR department staff members as some of the challenges that still persist post the Administrator’s era, all of which have contributed to the paralysis of organizational culture. University leaders can use the study findings as a tool to devise and implement radical change management interventions aiming at re-engineering HR departments that are operating abnormally, as well as for designing a responsive HR Strategic Architect. This study will contribute to the body of knowledge in the HR fraternity as there is a dearth of published studies on the internal challenges faces by HR Departments (both interpersonal and operational, which have the potential to hamper smooth operations of higher education institutions.

  15. Human Rights and Cultural Identity

    Directory of Open Access Journals (Sweden)

    John-Stewart Gordon

    2015-12-01

    Full Text Available Universal human rights and particular cultural identities, which are relativistic by nature, seem to stand in conflict with each other. It is commonly suggested that the relativistic natures of cultural identities undermine universal human rights and that human rights might compromise particular cultural identities in a globalised world. This article examines this supposed clash and suggests that it is possible to frame a human rights approach in such a way that it becomes the starting point and constraining framework for all non-deficient cultural identities. In other words, it is possible to depict human rights in a culturally sensitive way so that universal human rights can meet the demands of a moderate version of meta-ethical relativism which acknowledges a small universal core of objectively true or false moral statements and avers that, beyond that small core, all other moral statements are neither objectively true nor false.

  16. On the tenth anniversary of the "Universal Declaration on Bioethics and Human Rights".

    Science.gov (United States)

    Petrini, C

    2015-01-01

    In 2005 the representatives of 191 states meeting for the General Conference of UNESCO unanimously approved the "Universal Declaration on Bioethics and Human Rights". The Declaration is the only instrument of its kind: it was the first document adopted by a global organisation that addressed the whole range of issues with which bioethics is concerned and that is a legal instrument. Many of the principles affirmed in the Declaration had already been amply absorbed into the discipline of bioethics. All of them can be traced to the dignity and equality of every individual. The most evident novelty is to be found less in the content of the principles than in the balancing of individual and societal perspectives. Also in evidence are several compromises that were adopted in order to promote dialogue and mutual understanding.

  17. Why we need to find time for digital humanities: presenting a new partnership model at the University of Sussex

    Directory of Open Access Journals (Sweden)

    Jane Harvell

    2017-11-01

    Full Text Available Recognizing that academic libraries should develop and nurture strong, mutually beneficial relationships with researchers in digital humanities, the authors believe it is strategically important to invest time and resources exploring ideas and partnering with academic colleagues on projects. This approach can provide many unforeseen benefits to both the Library service and to the workforce. The article is based on our experience as Core Associates of the Sussex Humanities Lab at the University of Sussex. It outlines the impact this collaboration has had, including influencing working practices and culture within the Library, involvement in research bids, informing the development of new services, and addressing library questions using digital humanities methods. Most importantly, it exemplifies a new model of the librarian as equal partner in the research process.

  18. Development of a Centralized Human Resource Information System of Cavite State University

    Directory of Open Access Journals (Sweden)

    Jeffrey F. Papa

    2016-08-01

    Full Text Available This study focused in the automation and improvement of the Human Resource services. This includes managing of employees’ records, facilitating requests and processing of leave credits in accordance to the Civil Service Commission (CSC rules and regulation, tracking the employees' performance and skills, generating reports needed, and analyzing of employee information that will help in the decision making. This also includes attendance monitoring using biometrics, calculation of tardiness and absences of employees, and processing and printing of payroll. The system is developed using Visual Basic.Net, as the main programming language, SQL Server 2008 for back end database, MS Word and MS Excel for all needed reports. Two (2 units of computers that served as server and client, network devices and finger print biometric scanner completed the set-up of the developed system. The developed system consists of three (3 major application software or modules such as the Human Resource Information System, the Fingerprint Attendance System and the Payroll Alert System. The Human Resource Information System is used in the processing of employee records of the HR office. The Fingerprint Attendance System is used for getting the employee’s time-in and time-out for their attendance. The Payroll Alert System is used in notifying the accounting staff to generate the payroll on time. Test results based on efficiency in terms of CPU and memory usage, processing speed and accuracy of data, and consistency of outputs turned out favorable to the system. Forty respondents composed of faculty and administrative personnel of Cavite State University rated the system as “Excellent” with an overall mean of 4.73. It signifies that the developed system is acceptable and functions according to its preferred specifications.

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-04-01

    Full Text Available -Timothy P. Barnard, Cynthia Chou, Indonesian sea nomads; Money, magic, and fear of the Orang Suku Laut. London: RoutledgeCurzon, 2003, xii + 159 pp. -R.H. Barnes, Toos van Dijk, Gouden eiland in de Bandazee; Socio-kosmische ideeën op Marsela, Maluku Tenggara, Indonesië. Leiden: Onderzoekschool voor Aziatische, Afrikaanse en Amerindische studies (CNWS, Universiteit Leiden, 2000, 458 pp. [CNWS Publications 94.] -Andrew Beatty, Peter G. Riddell, Islam and the Malay-Indonesian world; Transmission and responses. Honolulu: University of Hawai'i Press, 2001, xvii + 349 pp. -Peter Boomgaard, Richard H. Grove ,El Niño - history and crisis; Studies from the Asia-Pacific region. Cambridge: White Horse Press, 2000, 230 pp., John Chappell (eds -Bernardita Reyes Churchill, Florentino Rodao, Franco y el imperio japonés; Imágenes y propaganda en tiempos de guerra. Barcelona: Plaza and Janés, 2002, 669 pp. -Matthew Cohen, Stuart Robson, The Kraton; Selected essays on Javanese courts. Translated by Rosemary Robson-McKillop. Leiden: KITLV Press, 2003, xxvi + 397 pp. [Translation series 28.] -Serge Dunis, Ben Finney, Sailing in the wake of the ancestors; Reviving Polynesian voyaging. Honolulu: Bishop Museum Press, 2003, 176 pp. [Legacy of excellence.] -Heleen Gall, Jan A. Somers, De VOC als volkenrechtelijke actor. Deventer: Gouda Quint, Rotterdam: Sanders Instituut, 2001, x + 350 pp. -David Henley, Harold Brookfield, Exploring agrodiversity. New York: Columbia University Press, 2001, xix + 348 pp. -David Hicks, Ernst van Veen ,A guide to the sources of the history of Dutch-Portuguese relations in Asia (1594-1797. With a foreword by Leonard Blussé. Leiden: Institute for the history of European expansion, 2001, iv + 378 pp. [Intercontinenta 24.], Daniël Klijn (eds -Nico Kaptein, Donald J. Porter, Managing politics and Islam in Indonesia. London: RoutledgeCurzon, 2002, xxi + 264 pp. -Victor T. King, Monica Janowski, The forest, source of life; The Kelabit of

  20. Universality of accelerating change

    Science.gov (United States)

    Eliazar, Iddo; Shlesinger, Michael F.

    2018-03-01

    On large time scales the progress of human technology follows an exponential growth trend that is termed accelerating change. The exponential growth trend is commonly considered to be the amalgamated effect of consecutive technology revolutions - where the progress carried in by each technology revolution follows an S-curve, and where the aging of each technology revolution drives humanity to push for the next technology revolution. Thus, as a collective, mankind is the 'intelligent designer' of accelerating change. In this paper we establish that the exponential growth trend - and only this trend - emerges universally, on large time scales, from systems that combine together two elements: randomness and amalgamation. Hence, the universal generation of accelerating change can be attained by systems with no 'intelligent designer'.

  1. Language Alternation in University Classrooms

    Science.gov (United States)

    Taha, T. A.

    2008-01-01

    This paper examines the alternate use of Arabic and English in the context of a university classroom, where a policy to use the former language in place of the latter was being implemented. Analysis of a sample of recorded university lectures of English and Arabic medium classes in sciences and humanities reveals that teachers use code switching,…

  2. An African Perspective on Human Rights.

    Science.gov (United States)

    Shiman, David

    1992-01-01

    Presents a series of classroom activities comparing differing views of human rights in the United Nations Universal Declaration of Human Rights and the African Charter on Human and People's Rights. Includes excerpts from the African Charter on Human and People's Rights and the full text of the Universal Declaration of Human Rights. (CFR)

  3. Watch Out for the Children: Army Policy and Child Soldiers

    Science.gov (United States)

    2016-06-01

    Arbor, MI: Fairfax Press, 1960), 63. 17 Emmy E . Werner, Reluctant Witnesses: Children’s Voices from the Civil War (Boulder, CO: Westview Press, 1998...Soldiers: From Violence to Protection (Cambridge, MA: Harvard University Press, 2006), 20–21. 71 Vera Achvarina and Simon F. Reich, “No Place to Hide...Conflict: Law, Policy and Practice (Leiden, Netherlands: Martinus Nijhoff Publishers, 2005), 23. 86 Tanya Zayed and Svenja Vollmer, E -Learning

  4. Book Reviews

    Directory of Open Access Journals (Sweden)

    Simon Kooijman

    1984-01-01

    Full Text Available - Gerard J. van den Broek, G. Varro, Orients, pour Georges Condominas. R. Hamayon, J. Matras-Troubetzkoy, J. Pouillon, L, Puiseux, Ch. Taillard, Toulouse, Editions Privat & Paris, Sudestasie, 1981, 345 pp., B. Condominas (eds. - M. Haddad, Nels Johnson, Islam and the politics of meaning in Palestinian nationalism, London: Kegan Paul International, 1982. - A. de Ruijter, Mary Douglas, In the active voice, London, Boston and Henley: Routledge and Kegan Paul, 1982, xi + 306 pp. - Peter Kloos, Paul Henley, The Panare. Tradition and change on the Amazonian frontier. New Haven, Yale University Press, 1982, 263 pp. - Peter Kloos, Conrad Phillip Kottak, Assault on Paradise. Social change in a Brazilian village. New York: Random House, 1983, 314 pp. - W.A. Shadid, M. van der Most van Spijk, Remember to be firm. Life histories of three Egyptian women, Women and development series, Cairo/Leiden 1982. 79 pp., H.Y. Fahmy, S. Zimmerman (eds. - W.A. Shadid, Marileen van der Most van Spijk, Eager to learn. An anthropological study of the needs of Egyptian village women; report of an experiment, Women and development series, Cairo/Leiden 1982. 84 pp. - W.A. Shadid, Marileen van der Most van Spijk, Who cares for her health? An anthropological study of women’s health care in a village in Upper Egypt, Women and development series, Cairo/Leiden 1982. 99 pp. - Willem van Schendel, Marvin Davis, Rank and rivalry: The politics of inequality in rural West Bengal, Cambridge: Cambridge University Press, 1983. - Simon Kooijman, Jerry W. Leach, The Kula, New perspectives on Massim exchange. Cambridge University Press, Cambridge, New York, New Rochelle, Melbourne, Sydney, 1983., Edmund Leach (eds. - Simon Kooijman, Martha Macintyre, The Kula. A Bibliography. Cambridge University Press, Cambridge, New York, New Rochelle, Melbourne, Sydney, 1983. - H. Dagmar, C.G. von Brandenstein, Names and substance of the Australian subsection system, The University of Chicago Press, N

  5. 76 FR 36152 - Notice of Inventory Completion: Western Michigan University, Anthropology Department, Kalamazoo...

    Science.gov (United States)

    2011-06-21

    ...: Western Michigan University, Anthropology Department, Kalamazoo, MI; Correction AGENCY: National Park... human remains and associated funerary objects. Western Michigan University, Department of Anthropology... may contact the Western Michigan University, Department of Anthropology. Disposition of the human...

  6. Human Cloning

    National Research Council Canada - National Science Library

    Johnson, Judith A; Williams, Erin D

    2006-01-01

    .... Scientists in other labs, including Harvard University and the University of California at San Francisco, intend to produce cloned human embryos in order to derive stem cells for medical research...

  7. Organization of educational process at the department of human anatomy of Saratov State Medical University n.a. V. I. Razumovsky

    Directory of Open Access Journals (Sweden)

    Bugaeva I0

    2017-06-01

    Full Text Available Human anatomy is one of the basic disciplines in the system of medical education. Knowledge in this area is necessary for the development of related theoretical subjects and constitutes a basis for studying clinical disciplines. Therefore the priority task of department of human anatomy is qualitative training of students at the modern level using classical and innovative pedagogical and computer technologies, being based on competence-based approach to training. In the article the features of organization of educational process at department of Human Anatomy of Saratov State Medical University n.a. V. I. Razumovsky, within the Federal state educational standard of the 3rd generation which key differences are considered: acquisition by students of cultural and professional competences.

  8. Positivity VII (Zaanen Centennial Conference)

    CERN Document Server

    Pagter, Ben; Gaans, Onno; Veraar, Mark

    2016-01-01

    This book presents the proceedings of Positivity VII, held from 22-26 July 2013, in Leiden, the Netherlands. Positivity is the mathematical field concerned with ordered structures and their applications in the broadest sense of the word. A biyearly series of conferences is devoted to presenting the latest developments in this lively and growing discipline. The lectures at the conference covered a broad spectrum of topics, ranging from order-theoretic approaches to stochastic processes, positive solutions of evolution equations and positive operators on vector lattices, to order structures in the context of algebras of operators on Hilbert spaces. The contributions in the book reflect this variety and appeal to university researchers in functional analysis, operator theory, measure and integration theory and operator algebras. Positivity VII was also the Zaanen Centennial Conference to mark the 100th birth year of Adriaan Cornelis Zaanen, who held the chair of Analysis in Leiden for more than 25 years and was ...

  9. Human Cloning

    Science.gov (United States)

    2006-07-20

    Human Fertilization and Embryology Authority (HFEA). A team of scientists headed by Alison Murdoch at the University of Newcastle received permission...not yet reported success in isolating stem cells from a cloned human embryo. A research team headed by Ian Wilmut at the University of Edinburgh...research group, headed by Douglas Melton and Kevin Eggan, submitted their proposal to a Harvard committee composed of ethicists, scientists and public

  10. In Defense of Soft Universalism

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Sten

    2011-01-01

    improved considerably since the time of the natural rights theories and the enlightenment. As a consequence prevailing international human rights are not the only possible human rights, and soft universalism is therefore partially open as regards the content of human rights, even though non discrimination...... human rights is the emerging global society, and human rights law is therefore best understood as (part of) the law of this emerging society. Seen in this way, human rights are an attempt to cope with a (partly) new situation, based on knowledge of human beings and society, a knowledge which has...... and other elements have some naturalness to them....

  11. Nõukogude anneksioon ja riigi järjepidevus : Eesti, Läti ja Leedu staatus rahvusvahelises õiguses 1940. a.-1991. a. ja pärast 1991. a : uurimus pingest normatiivsuse ja võimu vahel rahvusvahelises õiguses / Lauri Mälksoo ; tõlkinud Alar Hels

    Index Scriptorium Estoniae

    Mälksoo, Lauri, 1975-

    2005-01-01

    Tõlgitud väljaandest: Mälksoo, Lauri. Illegal Annexation and State Continuity : the case of the Incorporation of the Baltic States by the USSR. A Study of the Tension between Normativity and Power in International Law. - Leiden ; Boston : Brill, 2003. - 373 lk. - Bibl. lk. 341- 370 ja joonealustes märkustes. - (Monographs on International Law and Human Rights / Erik Castrén Institute of International Law and Human Rights ; 5). ISBN 90-411-2177-3

  12. Советская аннексия и государственный континуитет : международно-правовой статус Эстонии, Латвии и Литвы в 1940-1991 гг. и после 1991 г. : исслед�

    Index Scriptorium Estoniae

    Мялксоо, Лаури, 1975-

    2005-01-01

    Tõlgitud väljaandest: Mälksoo, Lauri. Illegal Annexation and State Continuity : the case of the Incorporation of the Baltic States by the USSR. A Study of the Tension between Normativity and Power in International Law. - Leiden ; Boston : Brill, 2003. - 373 lk. - Bibl. lk. 341- 370 ja joonealustes märkustes. - (Monographs on international law and human rights / Erik Castrén Institute of International Law and Human Rights ; 5). ISBN 90-411-2177-3

  13. Ukraine Open University: Its prospects in distance education development

    Directory of Open Access Journals (Sweden)

    Bohdan Shunevych

    2002-01-01

    Full Text Available The genesis, initiation, and expansion of distance education at the Ukraine Open International University for Human Development, located in Kyiv, will be examined in this case study, starting with a brief look at the positive changes taking place in Ukraine's traditional educational system, as well as recent developments in the country's distance education (DE system. To help readers understand the University's development from an insider's perspective, societal factors that currently influence its inter- and extra-institutional environment will also be examined. Next, the history, organizational structure, institutional activities, and background of the Ukraine Open International University for Human Development, along with the reasons driving the University's dual mode activities - both traditional and distance education - will be briefly analyzed. Included in this analysis is a summary of the challenges surrounding the application of both traditional and distance education models.The author concludes his case study by reflecting upon Ukraine Open International University for Human Development's experiences within the context of its being both a traditional education provider and new dual-mode distance education provider. Also discussed are some key indicators and predictions about what the future may hold for the University.

  14. Personnel of human anatomy department of Saratov State Medical University n.a. V. I. Razumovsky as the participants of the Great Patriotic War

    Directory of Open Access Journals (Sweden)

    Aleshkina O.Yu.

    2015-03-01

    Full Text Available The article provides evidence on participation of assistants who worked at the Department of Human Anatomy of Saratov State Medical University n.a. V. I. Razumovsky and took part in the Great Patriotic War.

  15. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-10-01

    ,Indonesian electoral behaviour; A statistical perspective. Singapore: Institute of Southeast Asian Studies, 2004, xli + 429 pp. [Indonesia's Population Series 2.], Evi Nurvida Arifin, Leo Suryadinata (eds -Hans Hägerdal, Arnaud Leveau, Le destin des fils du dragon; L'influence de la communauté chinoise au Viêt Nam et en Thaïlande. Paris: L'Harmattan, Bangkok: Institut de Recherche sur l'Asie de Sud Est Contemporaine, 2003, xii + 88 pp. -Han Bing Siong, A.W.H. Massier, Van recht naar hukum; Indonesische juristen en hun taal, 1915-2000. (Privately published, 2003, xiii + 234 pp. [PhD thesis, Leiden University.] -David Hicks, Andrew Berry, Infinite tropics; An Albert Russel Wallace anthology, with a preface by Stephen Jay Gould. London: Verso, 2002, xviii + 430 pp. -Carool Kersten, J. van Goor, Indische avonturen; Opmerkelijke ontmoetingen met een andere wereld. Den Haag: Sdu Uitgevers, 2000, 294 pp. -Lisa Migo, Robert Martin Dumas, 'Teater Abdulmuluk' in Zuid-Sumatra; Op de drempel van een nieuwe tijdperk. Leiden: Onderzoekschool CNWS, School voor Aziatische, Afrikaanse en Amerindische Studies, 2000, 345 pp. -John N. Miksic, Claude Guillot ,Historie de Barus, Sumatra; Le site de Lobu Tua; II; Étude archéologique et documents. Paris: Association Archipel, 2003, 339 pp. [Cahier d'Archipel 30.], Marie-France Dupoizat, Daniel Perret (eds -Sandra Niessen, Traude Gavin, Iban ritual textiles. Leiden: KITLV Press, 2003, xi + 356 pp. [Verhandelingen 205.] -Frank Okker, Jan Lechner, Uit de verte; Een jeugd in Indië 1927-1946. Met een nawoord van Gerard Termorshuizen. Leiden: KITLV Uitgeverij, 2004, 151 pp. [Boekerij 'Oost en West'.] -Angela Pashia, William D. Wilder, Journeys of the soul; Anthropological studies of death, burial and reburial practices in Borneo. Phillips ME: Borneo Research Council, 2003, vix + 366 pp. [Borneo Research Council Monograph Series 7.] -Jonathan H. Ping, Huub de Jonge ,Transcending borders; Arabs, politics, trade and Islam in Southeast Asia. Leiden

  16. The Challenge of University Autonomy

    DEFF Research Database (Denmark)

    Reilly, John; Turcan, Romeo V.; Bugaian, Larisa

    2016-01-01

    The authors introduce the reader to the book, providing a historical perspective and a current understanding of university autonomy. While appreciating the central role of the four dimensions of university autonomy – organisational, financial, human resource, and academic – the authors conjecture...... that a fuller understanding of university autonomy can only be obtained through a holistic view of the complex inter-relationships between stakeholders and policies which can reinforce and, equally, pull in opposite directions. This holistic view is represented in a model of institutional university autonomy......, which is discussed at length in the chapter. The authors conclude by presenting international case studies that give new insights and reinforce our understanding that the issues relating to institutional university autonomy are genuinely global....

  17. On the Role of Dust in the Universe

    Science.gov (United States)

    Martin, P. G.

    2004-05-01

    This article is a personal discourse on the various aspects of dust in the universe, its so-called role. My conclusion is that dust does make a difference. It directly alters the way we view the universe. It also changes the nature of the universe that we see. Finally, it is woven into the big picture of our own place in the universe and our understanding and responses. In arriving at this conclusion I explore a range of topics: the curse of extinction, dust as a photon converter, diversity, Galactic ecology, and a cosmic bawdy house. I also reflect on dust and (in)humanity. I argue that we must advance the post-Copernican enlightenment, so that a coherent understanding of our place in the universe, the big picture, becomes widely held, to provide a basis for improving life here and now, bringing humans into harmony with one another, other living fauna and flora, and the shared environment. Countering pernicious trends to the contrary will require a social revolution to accompany the scientific, through ``ideas transfer.'' This is much more challenging than propagating technology. Astronomers, particularly those versed in the beauties and multiple dimensions of dust in the universe, have an opportunity to participate, indeed to intervene. Since ``dust is us,'' this too is a role of dust in the universe, arguably the most profound if it is accepted that continued human existence has any importance.

  18. Olber's Paradox Revisited in a Static and Finite Universe

    Science.gov (United States)

    Couture, Gilles

    2012-01-01

    Building a Universe populated by stars identical to our Sun and taking into consideration the wave-particle duality of light, the biological limits of the human eye, the finite size of stars and the finiteness of our Universe, we conclude that the sky could very well be dark at night. Besides the human eye, the dominant parameter is the finite…

  19. A study of the relationship between variables from the model of human occupation and subjective well-being among university students in jordan.

    Science.gov (United States)

    Yazdani, Farzaneh; Jibril, Musa; Kielhofner, Gary

    2008-01-01

    The occupational role of a university student can create challenges that negatively affect subjective well-being. Cultural factors can make these problems particularly acute for students from Arab backgrounds. This study examined the relationship between variables derived from the Model of Human Occupation (MOHO) and Jordanian university students' subjective well-being. Using cluster sampling, a total of 670 participants were recruited from the undergraduate student body at the University of Jordan. Data were collected from these students using the Role checklist, the Occupational Self-Assessment, the Affectometer 2, and the Satisfaction with Life Scale. As hypothesized, reported roles, valuation of roles, perceived competence in volition, habituation, performance capacity/skills, and the environment were significantly correlated with subjective well-being. A discriminant analysis using the most strongly correlated items significantly classified students into known groups of high and low subjective well-being. Overall, MOHO-based variables offered an effective explanation of factors that influence subjective well-being in Jordanian university students.

  20. The University of Surrey database of elemental composition of human hair

    International Nuclear Information System (INIS)

    Altaf, W.J.; Akanle, O.A.; Admans, L.L.; Beasley, D.; Butler, C.; Spyrou, N.M.

    2004-01-01

    The elemental composition of human hair obtained from different studies at Surrey University over a period of 25 years has been recorded and forms part of a database, for biological and environmental samples, which is being developed. Instrumental neutron activation analysis (IAA), using reactor neutrons, was the principal method employed and from which reported data are presented. Elemental concentrations of Br, Ca, Ce, Cl, Co, Cr, Cs, F, Fe, Hf, K, Mg, Mn, Na, Rb, Sb, Sc, Se, V and Zn were obtained and recorded in the database. Chronological variations in two sets of subjects separated by a period of time of 16 years are also given. Variations in the concentration values of some elements related to the state of health and disease were reported for hair samples collected from subjects suffering from manic depression, senile dementia and breast cancer. Concentration values of some elements with relation to the nationality of subjects from Bulgaria, England, Kenya, Nigeria and Wales are presented and compared. This study is part of on-going research in the analysis of biomedical and bioenvironmental materials. The database is still in its infancy. (author)

  1. Normalization at the field level: fractional counting of citations

    OpenAIRE

    Leydesdorff, Loet; Opthof, Tobias

    2010-01-01

    Van Raan et al. (2010; arXiv:1003.2113) have proposed a new indicator (MNCS) for field normalization. Since field normalization is also used in the Leiden Rankings of universities, we elaborate our critique of journal normalization in Opthof & Leydesdorff (2010; arXiv:1002.2769) in this rejoinder concerning field normalization. Fractional citation counting thoroughly solves the issue of normalization for differences in citation behavior among fields. This indicator can also be used to obtain ...

  2. Insights into the effects of indicators on knowledge production in Astronomy

    OpenAIRE

    Heuritsch, Julia

    2018-01-01

    Nine interviews were conducted with astronomers from Leiden University, and a document analysis was performed on relevant institutional (self-) evaluation documents, annual reports, and CVs of the interviewees. The aim was to perform a qualitative study about the relationship between the research behaviour of astronomers and how their science is being evaluated. This study encompassed the funding and publication system as well as the indicators used to measure the scientific output, its quali...

  3. A human(e 'uni-versity': resisting scientism, technicism, and economism

    Directory of Open Access Journals (Sweden)

    J.J. Venter

    2006-07-01

    Full Text Available This article focuses on the issue of dehumanising knowledgegenerating procedures in the contemporary university. For this purpose different practical examples are analysed. It is argued that these dehumanising practices are rooted in present-day techno-scientistic elitism that has gone beyond the distinction between good and evil, and has developed into capitalistic pragmatism. Furthermore it is argued that these practices suppress critical reflection and creative alternatives in favour of gainful advantage within paradigmatic limitations. Real postmodern relativism thus does not exist; it is rather the absolutism of the economy and the market that determine the nature of knowledge-building processes.

  4. Learning Biases Predict a Word Order Universal

    Science.gov (United States)

    Culbertson, Jennifer; Smolensky, Paul; Legendre, Geraldine

    2012-01-01

    How recurrent typological patterns, or universals, emerge from the extensive diversity found across the world's languages constitutes a central question for linguistics and cognitive science. Recent challenges to a fundamental assumption of generative linguistics--that universal properties of the human language acquisition faculty constrain the…

  5. ADDRESSING SEXUAL VIOLENCE IN THE UNIVERSITY: HOW DO WE PREVENT AND PUNISH SEXUAL VIOLENCE AT CAMPUSES? A CASE OF MAKERERE UNIVERSITY.

    OpenAIRE

    Makoboza, Paul

    2016-01-01

    Sexual violence is a common human rights violation among campus students. Students within the university, faculty committees, and members of staff are not only involved in sexual violence, but also in addressing its causes. This thesis describes sexual violence victimization and perpetration awareness, its relationship with human right and punitive measures accorded to it in a sample of 150-university students. A cross sectional survey design was used to contact students through voluntary gat...

  6. 78 FR 65382 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  7. 78 FR 65369 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  8. 78 FR 65366 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  9. The universality of human rights: some pending questions

    African Journals Online (AJOL)

    Sidi Omar

    Cultural relativism, in brief, is the assertion that human values, far from being ... that particular human rights are like ‗essentially contested concepts' in which there ... There are obviously enough philosophical, ethical and legal arguments for ...

  10. Identification of subjects for social responsibility education at universities and the present activity at the university of Tokyo.

    Science.gov (United States)

    Karima, Risuke; Oshima, Yoshito; Yamamoto, Kazuo

    2006-01-01

    The management of corporate social responsibility (CSR) has recently become a critical concern for companies in advanced countries. For universities, there is a requirement to contribute to the promotion of CSR, resulting in graduates who have sufficient cognition of and a good attitude towards CSR. In addition, universities have social responsibilities, which can be called "University Social Responsibility (USR)." On the basis of the concepts of the guidelines for CSR in the "Green Paper," which was presented by the European Committee (EC) in 2001, we provide a perspective here on what factors dictate the establishment of education programs for social responsibilities at universities. These factors include an outline of the concepts and the significance of CSR, social ethics and the morals of higher education and research, compliances, human resource management, human rights, safety and health in academic settings, and various concerns regarding environmental safety and preservation. Additionally, through the concept postulated here for social responsible education, in this paper, we introduce the present activity at the University of Tokyo (UT) in terms of the education program for CSR and USR, proposing that the future establishment of university-wide education programs based on the concept of CSR and the value of sustainability is required at UT.

  11. "Taking the human out of human rights" human rights or group rights?

    Directory of Open Access Journals (Sweden)

    Bojanić Petar

    2015-01-01

    Full Text Available What interest me are the reasons why “human” or “human rights” could be important or possibly most important in constituting a group (hence the introduction of the complicated word “group” and “group right(s” in the subtitle. If I had to justify the existence of the latest debates on nature, justification and universality of human rights, on their distinction from other normative standards, on the philosophy and (legal foundation of human rights, on “Human Rights without (or with Foundations” (Raz, Tasioulas, Besson, then I would immediately conclude that this “process of grandiose concretization” of a complete fabrication is far from over. Despite the innumerable pacts and international conventions established after World War II, the slew of obligations to which states have agreed in the last few decades, the establishment of rights to secession or humanitarian intervention it is as if the constitution of classification of basic human rights and their universality is far from over. [Projekat Ministarstva nauke Republike Srbije, br. 43007

  12. The idea of university in a cosmopolitan perspective

    OpenAIRE

    Kemp, Peter

    2012-01-01

    The aim of this paper is to show why the humanities are more necessary than ever as part of the university education in our contemporary cosmopolitan age. We need the humanities if our educational institutions are to overcome the threats from narrow-minded politicians and business people to reduce education in schools and universities to simple instruction in management without guidance from the cultures of the world as expressed in art and literature, knowledge of languages, history, and phi...

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Janet Rodenburg

    1992-04-01

    Full Text Available - Leonard Y. Andaya, H.A. Poeze, Excursies in Celebes; Een bundel bijdragen bij het afscheid van J. Noorduyn als directeur-secretaris van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde. Leiden: KITLV Uitgeverij, 1991, 348 pp., P. Schoorl (eds. - Anne Booth, Adrian Clemens, Changing economy in Indonesia Volume 12b; Regional patterns in foreign trade 1911-40. Amsterdam: Royal Tropical Institute, 1992., J.Thomas Lindblad, Jeroen Touwen (eds. - A.P. Borsboom, James F. Weiner, The empty place; Poetry space, and being among the Foi of Papua New Guinea. Bloomington: Indiana University Press, 1991. - Martin van Bruinessen, Ozay Mehmet, Islamic identity and development; Studies of the Islamic periphery. London and New York: Routledge, 1990 (cheap paperback edition: Kula Lumpur: Forum, 1990, 259 pp. - H.J.M. Claessen, Timothy Earle, Chiefdoms: power, economy, and ideology. A school of American research book. Cambridge: Cambridge University Press, 1991. 341 pp., bibliography, maps, figs. - H.J.M. Claessen, Henk Schulte Nordholt, State, village, and ritual in Bali; A historical perspective. (Comparitive Asian studies 7. Amsterdam: VU University press for the centre for Asian studies Amsterdam, 1991. 50 pp. - B. Dahm, Ruby R. Paredes, Philippine colonial democracy. (Monograph series 32/Yale University Southeast Asia studies. New Haven: Yale Center for international and Asia studies, 1988, 166 pp. - Eve Danziger, Bambi B. Schieffelin, The give and take of everyday life; Language socialization of Kaluli children. (Studies in the social and cultural foundations of language 9. Cambridge: Cambridge University Press, 1991. - Roy Ellen, David Hicks, Kinship and religion in Eastern Indonesia. (Gothenburg studies in social anthropology 12. Gothenburg: Acta Universitatis Gothoburgensis, 1990, viii 132 pp., maps, figs, tbls. - Paul van der Grijp, Pierre Lemonnier, Guerres et festins; Paix, échanges et competition dans les highlands de Nouvelle

  14. Extra-Virgin Olive Oil with Natural Phenolic Content Exerts an Anti-Inflammatory Effect in Adipose Tissue and Attenuates the Severity of Atherosclerotic Lesions in Ldlr-/-.Leiden Mice.

    Science.gov (United States)

    Luque-Sierra, Amparo; Alvarez-Amor, Leticia; Kleemann, Robert; Martín, Franz; Varela, Lourdes M

    2018-05-15

    The present study investigates the effect of olive oils with different phenolic content in high-fat diets (HFDs) on hypertrophy and inflammation in adipose tissue and associated atherosclerosis, in the context of obesity. Ldlr-/-.Leiden mice were fed three different HFDs for 32 weeks and were compared with mice fed the standard low-fat diet (LFD). The different fats provided in the HFDs were lard (HFD-L), extra-virgin olive oil (EVOO; 79 mg kg -1 of phenolic compounds, HFD-EVOO), or EVOO rich in phenolic compounds (OL, 444 mg kg -1 of phenolic compounds, HFD-OL). All HFD-fed mice became obese, but only HFD-L-induced adipocyte hypertrophy. HFD-EVOO mice exhibited the greatest levels of Adiponectin in adipose tissue and presented atherosclerotic lesions similar to the LFD group, with a very low count of monocyte/macrophage compared with HFD-L and HFD-OL mice. Enrichment of the phenolic content of olive oil reduced the secretion of nitrites/nitrates in the aorta, but atherosclerosis was not attenuated in HFD-OL mice compared to other HFD mice. Consumption of olive oil with a natural content of phenolic compounds attenuates adipose tissue hypertrophy and inflammation and exerts antiatherosclerotic effects in mice. A higher phenolic content of olive oil did not provide further benefits in the prevention of atherosclerosis. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. A Human Right to Identity Formation? Identity, Politics, and the Universality of Human Rights

    Directory of Open Access Journals (Sweden)

    Richard T. Peterson

    2006-12-01

    Full Text Available This paper will build on ideas I presented at the previous conference (in 2003 on human rights at Mofid University. In that paper, I argued that it is a mistake to view human rights as the expression of a specific culture or historical identity (e.g., that of the “West”. Instead, human rights are better understood as historically emergent universals created in the conflict and interaction of various social groups with contrasting interests, cultural understandings, and identities. The aim of preserving a specific culture, religion, or historical identity against cultural imperialism or other kinds of domination can be supported by appealing to a human right to the formation of distinctive identities. Therefore this human right can contribute to a plurality of identities within the global network of societies that is emerging today. The aim of this paper is to develop this idea of a human right to identity formation دراین مقاله مخالفت خود را با تردید در جهان‌شمولی حقوق بشر اعلام کرده‌ام. این تردید، بر این باور مبتنی است که حقوق بشر، امری تحمیلی ازسوی غرب می‌باشد. من دلایلی برای انکار این نظر که حقوق بشر تماماً غربی است ارائه کرده، به وجوهی اشاره کردم که در واقع خیزش حقوق بشر، دست کم تا حدودی، ناشی از مبارزاتی است که با سلطة قدرت‌های غربی صورت می‌گیرد. این شیوه از استدلال، نیازمند انکار این مطلب نیست که زبان حقوق بشر گاه شکل سیاست‌هایی را گرفته که تمایز فرهنگ‌های دیگر را نمی‌توانند بفهمند (تشخیص دهند و از نابرابری جهانی ثروت و قدرت غفلت کرده‌اند، یا حتی از آن به نحو تلویحی حمایت

  16. Normative foundations of technology transfer and transnational benefit principles in the UNESCO Universal Declaration on Bioethics and Human Rights.

    Science.gov (United States)

    Faunce, Thomas Alured; Nasu, Hitoshi

    2009-06-01

    The United Nations Scientific, Education, and Cultural Organization Universal Declaration on Bioethics and Human Rights (UDBHR) expresses in its title and substance a controversial linkage of two normative systems: international human rights law and bioethics. The UDBHR has the status of what is known as a "nonbinding" declaration under public international law. The UDBHR's foundation within bioethics (and association, e.g., with virtue-based or principlist bioethical theories) is more problematic. Nonetheless, the UDBHR contains socially important principles of technology transfer and transnational benefit (articles 14, 15, and 21). This paper is one of the first to explore how the disciplines of bioethics and international human rights law may interact in the UDBHR to advance the policy relevance and health impact of such principles. It investigates their normative ancestry in the UDBHR, as well as relevant conceptual differences between bioethics and public international law in this respect, and how these may be relevant to their conceptual evolution and application.

  17. The Medical Humanities Effect: a Pilot Study of Pre-Health Professions Students at the University of Rochester.

    Science.gov (United States)

    Baker, Clayton J; Shaw, Margie Hodges; Mooney, Christopher J; Daiss, Susan Dodge-Peters; Clark, Stephanie Brown

    2017-12-01

    Qualitative and quantitative research on the impact of medical and health humanities teaching in baccalaureate education is sparse. This paper reviews recent studies of the impact of medical and health humanities coursework in pre-health professions education and describes a pilot study of baccalaureate students who completed semester-long medical humanities courses in the Division of Medical Humanities & Bioethics at the University of Rochester. The study format was an email survey. All participants were current or former baccalaureate students who had taken one or more courses in literature and narrative in medicine, bioethics, history of medicine, and/or visual arts and healthcare during the past four years. The survey gathered numerical data in several areas: demographic information, career plans, self-reported influence of coursework on educational and career plans, and self-reported influence of coursework on intellectual skills and abilities. It also gathered narrative commentary that elaborated on students' responses to the numerically-based questions. Notable findings from preliminary analysis of the data include higher scores of self-reported impact of the coursework on specific habits of mind and on preparedness for intended career rather than on gaining admission to future educational programs. Discussion of the results focuses on several potential future directions this type of study might take, including multi-center, longitudinal, and sequential approaches.

  18. Predictive value of a profile of routine blood measurements on mortality in older persons in the general population: the Leiden 85-plus Study.

    Directory of Open Access Journals (Sweden)

    Anne H van Houwelingen

    Full Text Available BACKGROUND: Various questionnaires and performance tests predict mortality in older people. However, most are heterogeneous, laborious and a validated consensus index is not available yet. Since most older people are regularly monitored by laboratory tests, we compared the predictive value of a profile of seven routine laboratory measurements on mortality in older persons in the general population with other predictors of mortality; gait speed and disability in instrumental activities of daily living (IADL. METHODOLOGY/PRINCIPAL FINDINGS: Within the Leiden 85-plus Study, a prospective population-based study, we followed 562 participants aged 85 years for mortality over five years. At baseline (age 85 years high-density lipoprotein cholesterol, albumin, alanine transaminase, hemoglobin, creatinin clearance, C-reactive protein and homocysteine were measured. Participants were stratified based on their number of laboratory abnormalities (0, 1, 2-4 and 5-7. The predictive capacity was compared with gait speed (6-meter walking test and disability in IADL (Groningen Activity Restriction Scale by C-statistics. At baseline, 418 (74% 85-year old participants had at least one laboratory abnormality. All cause mortality risk increased with increasing number of laboratory abnormalities to a hazard ratio of 5.64 [95% CI 3.49-9.12] for those with 5-7 laboratory abnormalities (p<0.001 compared to those without abnormalities. The c-statistic was 0.66 [95% CI 0.59-0.69], similar to that of gait speed and disability in IADL. CONCLUSIONS/SIGNIFICANCE: In the general population of oldest old, the number of abnormalities in seven routine laboratory measurements predicts five-year mortality as accurately as gait speed and IADL disability.

  19. [Sexual risk behaviours and PAP testing in university women vaccinated against human papillomavirus].

    Science.gov (United States)

    Fernández-Feito, Ana; Antón-Fernández, Raquel; Paz-Zulueta, María

    2018-05-01

    To estimate the association between the human papillomavirus (HPV) vaccine and sexual risk behaviour, as well as the participation in the Cervical Cancer Screening Program (CCSP). Cross-sectional study. School of Medicine and Health Sciences, School of Law, and School of Economics and Business (University of Oviedo). Female university students. Information was collected about contraceptive methods, sexual behaviours, HPV knowledge, and participation in the CCSP. Furthermore, proportions and odds ratio (OR) were estimated with their corresponding 95% confidence intervals (95%CI). Approximately two-thirds (67.7%) of the sample was vaccinated against HPV, and 216 women (65.3%) were sexually active. Barrier contraceptive methods were used by 67.6% during their current intimate relationships, being less frequent in non-vaccinated women (54.9% vs. 75.4% in vaccinated female students) (P=.002). The risk of having at least one sexual risk behaviour was higher in non-vaccinated women: OR2.29 (95%CI: 1.29-4.07). In addition, the probability of having a PAP test within the CCSP was higher in non-vaccinated women: OR2.18 (95%CI: 1.07-4.47). The prevalence of sexual risk behaviours in non-vaccinated women is elevated, and it is related to the lack of use of barrier contraceptive methods. The vaccination against HPV could affect sexual behaviours and the participation in the CCSP. Therefore, the information received by young people about contraceptive methods, sexually transmitted diseases, and cancer prevention should be reinforced. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  20. The Artful Universe Expanded

    Science.gov (United States)

    Barrow, John D.

    2005-07-01

    Our love of art, writes John Barrow, is the end product of millions of years of evolution. How we react to a beautiful painting or symphony draws upon instincts laid down long before humans existed. Now, in this enhanced edition of the highly popular The Artful Universe , Barrow further explores the close ties between our aesthetic appreciation and the basic nature of the Universe. Barrow argues that the laws of the Universe have imprinted themselves upon our thoughts and actions in subtle and unexpected ways. Why do we like certain types of art or music? What games and puzzles do we find challenging? Why do so many myths and legends have common elements? In this eclectic and entertaining survey, Barrow answers these questions and more as he explains how the landscape of the Universe has influenced the development of philosophy and mythology, and how millions of years of evolutionary history have fashioned our attraction to certain patterns of sound and color. Barrow casts the story of human creativity and thought in a fascinating light, considering such diverse topics as our instinct for language, the origins and uses of color in nature, why we divide time into intervals as we do, the sources of our appreciation of landscape painting, and whether computer-generated fractal art is really art. Drawing on a wide variety of examples, from the theological questions raised by St. Augustine and C.S. Lewis to the relationship between the pure math of Pythagoras and the music of the Beatles, The Artful Universe Expanded covers new ground and enters a wide-ranging debate about the meaning and significance of the links between art and science.

  1. Cosmology: The Universe in evolution

    International Nuclear Information System (INIS)

    Coyne, G.V.

    1995-01-01

    There are three principal pieces of evidence which, when taken together, support the notion that the Universe as a whole is evolving. These are: (a) the Hubble velocity-distance relationship; (b) the abundance of light elements in the Universe; and (c) the three degree cosmic background radiation. The best explanation of these observations is that the Universe began, if it had a beginning, in a hot dense state and it has been expanding and cooling down ever since. In the course of that process matter came to be out of energy, galaxies and stars formed, and you and I came to exist. In this process the emergence of organic material in general, and human beings in particular, seems to have required a very fine tuning of the evolutionary process itself. We do not yet have a definitive scientific explanation of that fine tuning and, therefore, we do not yet understand the linkage of the human being to cosmic evolution. But some interesting suggestions can be made. (author). Abstract only

  2. University as Regional Development Agent: A Counterfactual Analysis of an African University

    Science.gov (United States)

    Fongwa, Samuel N.; Wangenge-Ouma, Gerald

    2015-01-01

    The contribution of universities to regional development has in the last few decades gained significant currency. Inter alia, this contribution has been through steered national, regional, and institutional policies aimed at enhancing national development, good governance, human capital creation and innovation in an increasing knowledge-dependent…

  3. The idea of university in a cosmopolitan perspective

    Directory of Open Access Journals (Sweden)

    Peter Kemp

    2012-05-01

    Full Text Available The aim of this paper is to show why the humanities are more necessary than ever as part of the university education in our contemporary cosmopolitan age. We need the humanities if our educational institutions are to overcome the threats from narrow-minded politicians and business people to reduce education in schools and universities to simple instruction in management without guidance from the cultures of the world as expressed in art and literature, knowledge of languages, history, and philosophy.

  4. The Global Governance of Bioethics: Negotiating UNESCO's Universal Declaration on Bioethics and Human Rights (2005).

    Science.gov (United States)

    Langlois, Adèle

    2011-01-01

    UNESCO's Universal Declaration on Bioethics and Human Rights (2005) was drawn up by an independent panel of experts (the International Bioethics Committee) and negotiated by member states. UNESCO aimed for a participatory and transparent drafting process, holding national and regional consultations and seeking the views of various interest groups, including religious and spiritual ones. Furthermore, reflecting UNESCO's broad interpretation of bioethics, the IBC included medics, scientists, lawyers and philosophers among its membership. Nevertheless, several potential stakeholders-academic scientists and ethicists, government policy-makers and NGO representatives-felt they had not been sufficiently consulted or even represented during the Declaration's development. Better communications and understanding within and between national, regional and international layers of governance would help to avoid a recurrence of this problem in future negotiations.

  5. Assessing academic potential for university admission: The ...

    African Journals Online (AJOL)

    A Biographical Questionnaire (BQ) has been used in the Faculty of Humanities at the University of the Witwatersrand since the mid-80s, to identify potential to succeed at university among applicants who have not met the requirements for automatic admission. As the key instrument in a special admissions process, the

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Anthony Reid

    1998-01-01

    Full Text Available - J. Angerler, Jýrg Schneider, From upland to irrigated rice; The development of wet-rice agriculture in Rejang Musi, Southwest Sumatra. Berlin: Reimer, 1995, 214 pp. [Berner Sumatra-Forschungen.] - R.H. Barnes, Janet Hoskins, The play of time; Kodi perspectives on calendars, history, and exchange. Berkeley: University of California Press, 1993, xx + 414 pp. - Karin Bras, Christel Lýbben, Internationaler Tourismus als Faktor der Regionalentwicklung in Indonesien; Untersucht am Beispiel der Insel Lombok. Berlin: Dietrich Reimer, 1995, xiv + 178 pp. - Peter Boomgaard, Florentino Rodao, Espaýoles en Siam (1540-1939; Una aportaciýn al estudio de la presencia hispana en Asia Oriental. Madrid: Consejo Superior de Investigaciones Cientýficas, 1997, xix + 206 pp. [Biblioteca de Historia 32.] - Hans Hýgerdal, Winarsih Partaningrat Arifin, Babad Sembar; Chroniques de lýest javanais. Paris: Presses de lýýcole Francaise dýExtrýme Orient, 1995, 149 pp. [EFEO monographie 177.] - Els M. Jacobs, Gerrit J. Knaap, Shallow waters, rising tide; Shipping and trade in Java around 1775. Leiden: KITLV Press, 1996. [Verhandelingen van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde 172.] - Roy E. Jordaan, John Miksic, Ancient history. Singapore: Archipelago Press/Editions Didier Millet, n.d., 148 pp. [The Indonesian Heritage Series 1.] - Victor T. King, Penelope Graham, Iban shamanism; An analysis of the ethnographic literature. Canberra: Department of Anthropology, Research School of Pacific Studies, Australian National University, 1987 (reprint 1994, x + 174 pp. [Occasional Paper.] - Rita Smith Kipp, Simon Rae, Breath becomes the wind; Old and new in Karo religion. Dunedin: University of Otago Press, 1994, viii + 306 pp. - Niels Mulder, Raul Pertierra, Explorations in social theory and Philippine ethnography. Quezon City: University of the Philippines Press, 1997, xii + 262 pp. - Anthony Reid, Luc Nagtegaal, Riding the Dutch tiger; The Dutch East

  7. Honey From Maggots: Aura, Sacrifice, and the Human Universe in Charles Olson's "The Kingfishers"

    Science.gov (United States)

    Roethle, Christopher James

    In this thesis, I contend that some form of aura can be recovered from the ravages of technological reproduction described in Walter Benjamin's "The Work of Art in the Age of its Technological Reproducibility (Third Version)." Recovering this aura, however, may require adopting an aesthetic of immediacy through destruction and even wanton disposability (what Georges Bataille in his general economic theory calls "nonproductive expenditure") to ensure that, though routinely diluted and discarded, the split-second authenticity of a work remains, its radical ephemerality and formal irreproducibility opposing the enslaving, commodifying powers of the copy. The poetry and poetic theory of American poet Charles Olson, especially in his long poem "The Kingfishers" and his essays "Projective Verse" and "Human Universe," serves as an example of how an author might inscribe auratic energy along nonproductive, general economic lines.

  8. Purcell and NMR

    Science.gov (United States)

    Bloembergen, Nicolaas

    2012-02-01

    In 1946 and 1947 the author carried out research at Harvard University under the guydance of Professor Edward M.Purcell. The results were communicated in a frequently cited paper,often referred to as BPP, after the authors Bloembergen, Purcell and Pound. The same material appeared in my 1948 Ph. D. Leiden thesis ``Nuclear Magnetic Relaxation.'' Some personal interactions with Ed Purcell and Bob Pound in these early and in later years at Harvard will be recounted.

  9. Travel, infection and immunity

    OpenAIRE

    Soonawala, Darius

    2016-01-01

    Preface: The content of this thesis is based on research that was conducted at the travel and vaccination clinic at Leiden University Medical Centre (LUMC). This clinic provides pre-travel care to the general population, and to special groups of travellers, such as patients who use immunosuppressants or who have chronic diseases. The clinic is closely connected to the department of Infectious Diseases at LUMC. The setting of a travel clinic within an academic medical hospital, provides unique...

  10. University Students and Ethics of Computer Technology Usage: Human Resource Development

    Science.gov (United States)

    Iyadat, Waleed; Iyadat, Yousef; Ashour, Rateb; Khasawneh, Samer

    2012-01-01

    The primary purpose of this study was to determine the level of students' awareness about computer technology ethics at the Hashemite University in Jordan. A total of 180 university students participated in the study by completing the questionnaire designed by the researchers, named the Computer Technology Ethics Questionnaire (CTEQ). Results…

  11. Achieving Quality Assurance in Nigeria University System through ...

    African Journals Online (AJOL)

    This paper examines how quality assurance can be attained through Strategic Human Resources Development in Nigerian University system. The purpose is to ensure quality control and maintenance of acceptable standards in the University system. To seek solution to the problem, three research questions were posed.

  12. Factors Influencing Academic Failure of University Students

    Science.gov (United States)

    Khan, Yousaf Ali; Ahamad, Zahoor; Kousar, Sadia

    2013-01-01

    There was a close link between education and development. Education played a vital role in human capital formation. Academic failure from university was a problem that had became a serious concern for higher education institutions. This study presented the result of a recent investigation at the University of Gujrat that attempted to identify the…

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    M. Schoffeleers

    1989-10-01

    Full Text Available - Victoria J. Baker, Anthony Jackson, Anthropology at home, ASA monographs 25, London: Tavistock Publications, 1987, 221 pages. - Thomas Bargatzky, Martin A. van Bakel, Private politics; A multi-disciplinary approach to ‘Big-Man’ systems, Studies in Human Society, Vol. I, Leiden: E.J. Brill, 1986. x, 220 pp., illustrations, maps, index., Renée R. Hagesteijn, Pieter van de Velde (eds. - W.E.A. van Beek, Victor W. Turner, The anthropology of experience, (with an epilogue by Clifford Geertz. Urbana and Chicago: University of Illinois Press, 1986., Edward M. Bruner (eds. - W. van den Broeke, H. Meyer, De Deli Spoorweg Maatschappij; Driekwart eeuw koloniaal spoor, Zutphen: Walburg Pers, met medewerking van F.A.J. Heckler. 1987; 152 blz. - R. Buijtenhuijs, S. Bernus et al., Le fils et le neveu: Jeux et enjeux de la parenté tourarègue, Cambridge University Press, Cambridge/Editions de la Maison des Sciences de l’Homme, Paris, 1986, XI, 343 pp. - R. Buijtenhuijs, Dominique Casajus, La tente dans la solitude: La société et les morts chez les Touaregs Kel Ferwan, Cambridge University Press, Cambridge/Editions de la Maison des Sciences de l’Homme, Paris, 1987, 390 pp. - H.J.M. Claessen, Christine Ward Gailey, Kinship to kingship; Gender hierarchy and state formation in the Tongan Islands. Austin: University of Texas Press (Texas Press Sourcebooks in Anthropology, No. 14., 1987. 326 pp., figs., index, bibl. - Alfred E. Daniëls, Richard B. Davis, Muang metaphysics, Bangkok: Pandora Press,1984. - Alfred E. Daniëls, Gehan Wijeyewardene, Place and emotion in northern Thai ritual behaviour, Bangkok: Pandora Press, 1986. - P.M.H. Groen, Jacques van Doorn, The process of decolonization 1945-1975; The military experience in comparitive perspective, CASP publications no. 17, Erasmus Universiteit Rotterdam, 1987, 46 pp., Willem J. Hendrix (eds. - Rosemarijn Hoefte, Luis H. Daal, Antilliaans verhaal. Zutphen: De Walburg Pers, 1988, Ted

  14. What if there were no universities?

    Science.gov (United States)

    Vasbinder, Jan W

    2017-12-01

    To a large extent, the pursuit of science takes place in universities. In this essay, I ask the following questions. Supposing there were no universities, and that all the knowledge mankind has ever collected and generated is somehow accessible, would we invent universities to make this knowledge available to address the problems humanity faces? What should those universities perform, and what role would science play in such universities? To look for answers to those questions, I consider the nature of the problems dealt with by science, the knowledge needed to address those problems, the gap between the two, the need for interdisciplinarity and the need to educate the leaders of the future, and finally, the boundaries of scientific knowledge. © 2017 The Institute of Psychology, Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  15. Psychological Universals: What Are They and How Can We Know?

    Science.gov (United States)

    Norenzayan, Ara; Heine, Steven J.

    2005-01-01

    Psychological universals, or core mental attributes shared by humans everywhere, are a foundational postulate of psychology, yet explicit analysis of how to identify such universals is lacking. This article offers a conceptual and methodological framework to guide the investigation of genuine universals through empirical analysis of psychological…

  16. Social Foundations of Human Space Exploration

    CERN Document Server

    Dator, James A

    2012-01-01

    Social Foundations of Human Space Exploration presents a uniquely human perspective on the quest to explore space and to understand the universe through the lens of the arts, humanities, and social sciences. It considers early stories about the universe in various cultures; recent space fiction; the origins and cultural rationale for the space age; experiences of humans in space and their emerging interactions with robots and artificial intelligence; how humans should treat environments and alien life; and the alternative futures of space exploration and settlement.

  17. The life and times of religion and human rights

    NARCIS (Netherlands)

    Gaay Fortman, B. de; Salih, Mohamed

    2003-01-01

    Seen from a human perspective and as communal protection of human dignity, human rights are universal challenges to which all major traditions of the human family have subscribed. However, ways and means as to the realisation of this universal human ideal have been subject to controversy because of

  18. Development of a sensitive and specific epitope-blocking ELISA for universal detection of antibodies to human enterovirus 71 strains.

    Directory of Open Access Journals (Sweden)

    Fang He

    Full Text Available BACKGROUND: Human Enterovirus 71 (EV71 is a common cause of hand, foot and mouth disease (HFMD in young children. It is often associated with severe neurological diseases and mortalities in recent outbreaks across the Asia Pacific region. Currently, there is no efficient universal antibody test available to detect EV71 infections. METHODOLOGY/PRINCIPAL FINDING: In the present study, an epitope-blocking ELISA was developed to detect specific antibodies to human EV71 viruses in human or animal sera. The assay relies on a novel monoclonal antibody (Mab 1C6 that specifically binds to capsid proteins in whole EV71 viruses without any cross reaction to any EV71 capsid protein expressed alone. The sensitivity and specificity of the epitope-blocking ELISA for EV71 was evaluated and compared to microneutralization using immunized animal sera to multiple virus genotypes of EV71 and coxsackieviruses. Further, 200 serum sample from human individuals who were potentially infected with EV71 viruses were tested in both the blocking ELISA and microneutralization. Results indicated that antibodies to EV71 were readily detected in immunized animals or human sera by the epitope blocking ELISA whereas specimens with antibodies to other enteroviruses yielded negative results. This assay is not only simpler to perform but also shows higher sensitivity and specificity as compared to microneutralization. CONCLUSION: The epitope-blocking ELISA based on a unique Mab 1C6 provided highly sensitive and 100% specific detection of antibodies to human EV71 viruses in human sera.

  19. Realizing right to health through universal health coverage

    Directory of Open Access Journals (Sweden)

    ANJALI Singh

    2014-07-01

    Full Text Available Recognition of right to health is an essential step to work towards improvement of public health and to attain highest standard of physical and mental health of the people. Right to health in India is implicit part of right to life under Article 19 mentioned in the Constitution of India but is not recognized per se. Universal Health Coverage adopts rights based approach and principles of universality, equity, empowerment and comprehensiveness of care. The Universal Coverage Report of India makes recommendations in six identified areas to revamp the health systems in order to ensure right to health of Indians. These areas are: health financing and financial protection; health service norms; human resources for health; community participation and citizen engagement; access to medicines, vaccines and techno- logy; management and institutional reforms. This paper attempts to determine the ways inwhich Universal Health Coverage can make a contribution in realizing right to health and thus human rights in developing countries.

  20. Companies' human capital required for collaboration

    DEFF Research Database (Denmark)

    Albats, Ekaterina; Bogers, Marcel; Podmetina, Daria

    building, relationship building, IPR management and negotiation for the context of collaboration with universities. Our research has revealed an importance of expectation management skills for university-industry collaboration (UIC) context. We found that human capital for UIC is to be continuously......Universities are widely acknowledged as an important source of knowledge for corporate innovation, and collaboration with universities plays an important role in companies’ open innovation strategy. However, little is known about the human capital components required for collaboration...... with universities. Analysing the results of the survey among over 500 company managers we define the universal employees’ skills required for company’ successful collaborations with external stakeholders. Then through analysing qualitative interviews data we distinguish between these skills and capabilities...

  1. Heads of administration from the University of Bergen, Norway, visiting CERN

    CERN Multimedia

    AUTHOR|(CDS)2094367

    2017-01-01

    The faculty directors and heads of administration from the University of Bergen, Norway, visited CERN on November 6 2017. The group was received by Martin Steinacher, Director for Finance and Human Resources, Prof. Egil Lillestøl, honorary staff member and Jens Vigen, head librarian. The delegation from Bergen included: Kjell Bernstrøm, University Director, Øystein Iversen, Director for Faculty of Law, Tore Tungodden, Assistant University Director, Kari Fuglseth, Deputy Director General University Director´s Office, Laurice Høie, Higher Executive Officer University Director´s Office, Ingar Myking, Deputy Director General University Director´s Office, Alette Mykkeltvedt, Director for Faculty of Social Sciences, Elisabeth Lysebo, Director for Faculty of Mathematics and Natural Sciences, Kim Ove Hommen, Director for Faculty of Humanities, Kristin Nodland, Head of Administration University Museum, Synnøve Myhre, Director for Faculty of Fine Art, Music and Design, Ørjan Hauge, Assistant Director for Facu...

  2. How to build a universe

    CERN Document Server

    Cox, Brian; Feachem, Alexandra

    2017-01-01

    The Infinite Monkey Cage, the legendary BBC Radio 4 programme, brings you this irreverent celebration of scientific marvels. Join us on a hectic leap through the grand and bizarre ideas conjured up by human imagination, from dark matter to consciousness via neutrinos and earthworms. Professor Brian Cox and Robin Ince muse on multifaceted subjects involved in building a universe, with pearls of wisdom from leading scientists and comedians peppered throughout. Covering billions of concepts and conundrums, they tackle everything from the Big Bang to parallel universes, fierce creatures to extraterrestrial life, brain science to artificial intelligence. How to Build a Universe is an illuminating and inspirational celebration of science - sometimes silly, sometimes astounding and very occasionally facetious.

  3. Corporate Universities and Corporation- University Partnerships in Thailand: Complimenting Education in Learning, Leadership and Change

    Directory of Open Access Journals (Sweden)

    Oliver S. Crocco

    2017-04-01

    Full Text Available With an estimated workforce of 285 million and the establishment of the Association of Southeast Asian Nations (ASEAN Economic Community in 2015, ASEAN faces vast challenges in human resource development (HRD and higher education. These challenges in Thailand have resulted in the rise of corporate universities and corporation-university partnerships. Corporate partnerships in education adapt quickly to industry needs and are increasingly popular and complimentary to traditional higher education. This research looks at one corporate university and one corporation-university partnership to investigate how, if at all, corporate universities and partnerships address HRD issues such as adult learning, leadership development, organisational change, corporate social responsibility (CSR, as well as ethical and global issues. This research finds initial evidence that corporate educational strategies address a variety of HRD issues and have the potential to revolutionise and compliment higher education in Thailand in a way that drives the nation toward a more sustainable future.

  4. A General Education Course in Cultural Astronomy: Exploring the Universe Through Human Eyes

    Science.gov (United States)

    Larsen, Kristine

    2017-01-01

    Astronomy courses for non-science majors (often referred to as Astro 101) are the bread and butter of the general education service obligation of astronomy faculty and programs across the US. Their content has traditionally been a general survey of the solar system, stars and galaxies, or even the entire universe. However, because the audience is students who will not be continuing on in astronomy, there is actually no need to cover a broad range of specific topics. Rather, it is more important to concentrate on the scientific process, and hopefully leave the student with an understanding of the relevance of science in everyday life, regardless of his or her major. As a result, some faculty prefer a more interdisciplinary focus for their Astro 101 classes, for example courses on the search for extraterrestrial life. Another option for general education astronomy courses is what has become known as cultural astronomy. Cultural astronomy focuses on the ways in which astronomical knowledge and belief influences human behavior and social structures. Under this umbrella fall two important areas of study, archaeoastronomy (concentrating on ancient cultures) and enthoastronomy (focusing on extant cultures). Such interdisciplinary courses draw heavily upon archaeology, history, anthropology, art, and other fields more traditionally aligned with the humanities and social sciences than the natural sciences, and therefore can be attractive to students in these non-science majors. In such courses, students experience the “humanity” of science: the important connections between science and the human experience, and how experts in myriad fields contribute in meaningful ways to our understanding of how astronomical knowledge has been constructed and disseminated across time and space. This poster describes the content and pedagogy of a general education course in cultural astronomy for non-science majors that stresses hands-on and experiential learning, including the use of

  5. Building Sustainable Capacity with University Partnerships

    Science.gov (United States)

    Harris, J. M.

    2013-05-01

    Universities can play an important role in building scientific and technical capacity by providing educational opportunities for local and regional populations in developing countries. These opportunities may be short term or long term through for example faculty exchanges, student exchanges, and collaborative teaching and research activities. As the demand for talented graduates expands in developing countries, local universities face competition for students, lecturers, and professors from the same industries and communities they serve. This competition is in many ways counterproductive to building the sustainable human resource that is needed to support local development, management, and governance. Such competition is particularly evident for top science and engineering students in energy rich countries. University partnerships, e.g., in particular those between universities in OECD countries and universities in developing countries, have an important role to play in bridging the gap between today's lack of capacity and a sustainable human resource for the future. Such university partnerships, however, face many challenges, some of which can be traced to organizational and cultural differences In this presentation, I will discuss how university partnerships are formed, some of the benefits to partners, and some pitfalls to avoid during implementation of university partnerships. The examples are taken from Stanford partnerships that involve geoscience and engineering, and will include representative goals and content of the example partnerships. These partnerships I'll describe are actually trilateral, with partners from two or more universities and a private company or government agency. I conclude the presentation with a brief discussion on multiculturalism, perhaps the most important consideration when planning a partnership between diverse organizations. Organizers of partnerships must recognize the fact that multiculturalism and diversity are assets that

  6. Chapter 8. Ionisation radiation and human organism. Radioactivity of human tissues

    International Nuclear Information System (INIS)

    Toelgyessy, J.; Harangozo, M.

    2000-01-01

    This is a chapter of textbook of radioecology for university students. In this chapter authors deal with ionisation radiation and human organism as well as with radioactivity of human tissues. Chapter consists of next parts: (1) Radiation stress of human organism; (2) Radioactivity of human tissues and the factors influencing radioactive contamination; (3) Possibilities of decreasing of radiation stress

  7. Together with Research Centers and Universities

    Directory of Open Access Journals (Sweden)

    Nuno Domingos Garrido

    2016-10-01

    Full Text Available The Journal Motricidade has always been walking in parallel with the scientific communities. We found that the affiliation of most authors has, nearly always, a University (Uni or a Research Center (RC. In fact it is almost impossible to conduct research outside these two universes. In this sense, Uni and RC feed the most, if not all, of scientific journals worldwide. By this I mean that is in the interest of Motricidade to be associated with high-quality RC and Uni equally recognized. With regard to RC, Motricidade will publish this year a supplement of the International Congress of Research Centre in Sports Sciences, Health Sciences and Human Development (CIDESD. This RC has conducted research in a variety of areas within the Sport Sciences and Health and always with high recognition and associated publications. It was not by chance that this RC was evaluated with ‘very good’ by the Portuguese Foundation for Science and Technology (FCT panel and has been granted funding. This Congress, which takes place every two years, targets to converge research and high level practices within these three areas: Sports, Health and Human Development. The 2016 CIDESD edition is dedicated to "Exercise and Health, Sports and Human Development" and will be held at the University of Évora, between 11 and 12 November of 2016. The readers can check the program in the following link http://gdoc.uevora.pt/450120 and get more information in the Congress Site available at http://www.cidesd2016.uevora.pt/. With regard to Uni, Motricidade signed a cooperation protocol with the University of Beira Interior (UBI in May of 2016, involving the development and dissemination of scientific knowledge in Sports Sciences, Psychology, Human Development and Health. At the present, UBI hosts more than 6,000 students spread across five faculties - Arts & Letters, Sciences, Health Sciences, Humanities and Social Sciences and Engineering. When looking at the rankings, for instance

  8. University engagement and regional sustainability initiatives

    DEFF Research Database (Denmark)

    Lehmann, Martin; Christensen, Per; Thrane, Mikkel

    2009-01-01

    With an outset in ‘sustainability' defined as a continuous process requiring balance between (the emergence of) problems and our ability and capability to solve them using four distinct capitals available, i.e. natural, production, human and intellectual, and social capital, a model of universities...... University, Denmark, the linkages (actual, potential and missing) between academic work in research and education and sustainability initiatives are explored. The focus is both on the university's core activities as a provider of research and education and on the university's activities as an organisation, i...... societal benefit would be the ability to better cope with emerging problems endangering the sustainable development of our societies. It is concluded that Aalborg University with its long tradition for project-based and problem-oriented learning in fact has every opportunity to be able to lead by example...

  9. Neoliberalism and University Education in Sub-Saharan Africa

    Directory of Open Access Journals (Sweden)

    James R. Ochwa-Echel

    2013-09-01

    Full Text Available This article reviews the history of university development in Sub-Saharan Africa (SSA and discusses the impact of neoliberal policies. This will be followed by an examination of the problems facing universities in the region. The following questions will be explored: (a Are the existing universities in SSA serving the development needs of the region? (b Are these universities up to the task of moving SSA out of the predicaments it faces such as famine, HIV/AIDS, poverty, diseases, debt, and human rights abuses? Finally, the article argues that for universities to play a role in the development of the region, a new paradigm that makes university education a public good should be established.

  10. Roots of Violence in Indonesia, Freek Colombijn & J. Thomas Lindblad (eds

    Directory of Open Access Journals (Sweden)

    Glenn Smith

    2013-01-01

    Full Text Available This volume contains papers presented at the Leiden University workshop on “Violence in Indonesia. Its historical roots and its contemporary manifestations” in December 2000. The revised papers take into account developments up to early 2001. This useful anthology of essays is divided into three parts. The first part, “Historical continuity,” paints through case studies a picture of violence as an ever-present part of the Indonesian state. The second part, “Army violence,” specifically looks ...

  11. The low-energy experiment on EXOSAT

    International Nuclear Information System (INIS)

    Bleeker, J.A.M.

    1975-01-01

    The present concept of the Low-Energy-Experiment (LEE) for EXOSAT was proposed by a collaboration of the X-ray astronomy groups at Mullard Space Science Laboratories at University College London, the Space Research Laboratory at Utrecht and the Cosmic Ray Working Group at Leiden. In the following paragraphs the major characteristics of the instrumentation and the expected scientific return will be discussed. The summary comprises both the approved baseline configuration and the proposed option of a small imaging telescope

  12. An Artist in the University Medical Center. Review.

    Science.gov (United States)

    James, A. Everette, Jr.

    1991-01-01

    Reviews "An Artist in the University Medical Center" (M. Lesser, New Orleans: Tulane University Press, 1989), in which the artist captures the human side of the complex Tulane Medical Center in New Orleans (Louisiana). The interplay of drawings, etchings, watercolors, and prose conveys traditions of nurturing in the hospital. (SLD)

  13. Beyond the Letter of the Law: Accessibility, Universal Design, and Human-Centered Design in Video Tutorials

    Directory of Open Access Journals (Sweden)

    Amanda S. Clossen

    2014-05-01

    Full Text Available This article demonstrates how Universal and Human-Centered Design approaches can be applied to the process of library video tutorial creation in order to enhance accessibility. A series of questions that creators should consider in order to focus their design process is discussed. These questions break down various physical and cognitive limitations that users encounter, providing a framework for future video creation that is not dependent on specific software. By approaching accommodations more holistically, videos are created with accessibility in mind from their conception. Working toward the ideal of a video tutorial that is accessible to every user leads to the creation of more clearly worded, effective learning objects that are much more inclusive, making instructional concepts available to users of all abilities.

  14. ISLAM AND HUMAN RIGHTS IN INDONESIA: An Account of Muslim Intellectuals’ Views

    Directory of Open Access Journals (Sweden)

    Ahmad Nur Fuad

    2007-08-01

    Full Text Available The issue of Islam and human rights has become important issue in Indonesia at least since the last two decades. Indonesian Muslims have developed two different approaches to human rights: in complete agreement with the declaration of universal human rights; and in resistance to that declaration and developing understanding that Islam encompasses human rights values. The article argues for its part that human rights are not absolutely universal, because they are based chiefly on Western values, structures, ethics and morality. For that, it is reasonable to question their universality. The present article focuses on how Indonesian Muslim intellectuals conceive of human rights and Islamic values as they perceive the two. Specifically, it focuses on four principal issues in human rights discourse: freedom of opinion, religious freedoms, rights of women, and criminal law. The authors reveal in the conclusion that although some Indonesian Muslim intellectuals admit that universal human rights are truly universal, they still see differences in certain cases, due to differencesin socio-cultural background. They have tried to affect a synthesis between the universality and particularity of both Islamic and universal human rights in order to make both fit within the Indonesian context.

  15. transformation, theology and the public university in south africa

    African Journals Online (AJOL)

    theological task of theology at a public university – the articulation of transcendence ..... position of theology at the university and its relationship to the humanities; ..... preference; energy foci; international networking, and spatial arrangement. ... geographic location, denominational involvement, personality and theology of ...

  16. Theorizing University Identity Development: Multiple Perspectives and Common Goals

    Science.gov (United States)

    MacDonald, Ginger Phillips

    2013-01-01

    Universities articulate their identities during moments of organizational change. The process of development of university identity is herein explored from multiple theoretical strands: (a) industrial/organizational psychology, (b) human development/social psychology, (c) marketing, and (d) postmodern sociological. This article provides an…

  17. The Universal Protein Resource (UniProt)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase...

  18. 75 FR 52021 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Science.gov (United States)

    2010-08-24

    ... University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. Notice... University College of Dentistry, New York, NY. The human remains were removed from Port Clarence, Nome County... the human remains was made by New York University College of Dentistry professional staff in...

  19. Handgrip strength at midlife and familial longevity : The Leiden Longevity Study

    NARCIS (Netherlands)

    Ling, Carolina H.Y.; De Craen, Anton J.M.; Eline Slagboom, P.; Westendorp, Rudi G.J.; Maier, Andrea B.

    2012-01-01

    Low handgrip strength has been linked with premature mortality in diverse samples of middle-aged and elderly subjects. The value of handgrip strength as marker of "exceptional" human longevity has not been previously explored. We postulated that the genetic influence on extreme survival might also

  20. The Core Meaning of Human Dignity

    Directory of Open Access Journals (Sweden)

    Rinie Steinmann

    2016-06-01

    Full Text Available The concept of human dignity is relatively new in international and domestic constitutional law. Dignity is protected as a value or a right, or both, in international law and many domestic jurisdictions. It is difficult to define human dignity in a legal context, as the concept is not defined in the first international document which recognizes inherent human dignity and the protection thereof, the Universal Declaration of Human Rights (1946 and many international (and national documents enacted thereafter. Despite dissensus regarding the widespread use of the concept, dignity has come to display three elements in constitutional adjudication post World War Two: the ontological element which entails that human beings have equal inherent human dignity that cannot be waived or diminished; the second element being the claim that inherent human dignity has to be recognised and respected; and the limited-state claim as the third element which entails that states have a positive obligation to progressively realise human dignity through the mechanism of socio-economic rights. It is widely accepted that these elements root in Kantian moral ethics which holds that man's autonomy is based upon universal dignity, as a result of which man should never be used as a means to an end, but only as a means in himself. Kant expressed this idea through formulation of a categorical imperative, namely that everyone's inherent human dignity has to be respected and protected universally. The preamble of the Universal Declaration of Human Rights (1946, article 1(1 of the German Basic Law and section 10 of the Constitution of the Republic of South Africa, 1996 embody the elements of Kant's categorical imperative. As a result, the three elements are applied as a definitional term of human dignity in German and South African constitutional adjudication. Based on these elements, it can be argued that the current idea of universal inherent dignity, at least in German and

  1. The City as a Focus for Human Capital Migration: Towards a Dynamic Analysis of University Human Capital Contributions

    NARCIS (Netherlands)

    Benneworth, Paul Stephen; Herbst, Mikolaj

    2015-01-01

    Universities' contributions to urban development frequently focus on their micro- or macro-scale effects, ignoring the meso-scale effects they have on inter-territorial relationships. Although universities are seen as an essential part of the recipe for successful urban development, there is a

  2. The Consequences of Delaying Entrance into University

    DEFF Research Database (Denmark)

    Foley, Kelly; Groes, Fane

    Because the returns to education depend on the nite horizon of individuals' working lives, human capital models predict that if an individual is going to attend university, she should do so as soon as possible. Delaying university can also mean individuals have fewer years in which to accumulate...... post-schooling experience. In this paper, we use Danish administrative data to estimate the wage losses experienced by individuals who accumulate less post-schooling experience because they postponed entry into university following high school. All else equal, experience-related costs of delaying...

  3. The Elusive Universal Post-Mortem Interval Formula

    Energy Technology Data Exchange (ETDEWEB)

    Vass, Arpad Alexander [ORNL

    2011-01-01

    The following manuscript details our initial attempt at developing universal post-mortem interval formulas describing human decomposition. These formulas are empirically derived from data collected over the last 20 years from the University of Tennessee's Anthropology Research Facility, in Knoxville, Tennessee, USA. Two formulas were developed (surface decomposition and burial decomposition) based on temperature, moisture, and the partial pressure of oxygen, as being three of the four primary drivers for human decomposition. It is hoped that worldwide application of these formulas to environments and situations not readily studied in Tennessee will result in interdisciplinary cooperation between scientists and law enforcement personnel that will allow for future refinements of these models leading to increased accuracy.

  4. Environmental Waste Management in a School Hospital and in a Laboratory of Human Anatomy of a University

    Directory of Open Access Journals (Sweden)

    Kira Lusa Manfredini

    2013-12-01

    Full Text Available The scientific and professional activities developed in a Hospital School and a Laboratory of Human Anatomy of a university can generate parallel, chemical residues from various degrees of angerousness, which may require physical treatment and / or suitable chemical, before being sent to final destination. The General Hospital (GH generates monthly 10 L of xylenes and 50 L of glutaraldehyde to provide ass instance to their patients. Already the Laboratory of Human Anatomy of University de Caxias do Sul (AL-UCS uses more than 10,000 liters for preserving corpses in tanks. The present study aims to analyze the chemical waste management of the GH and the AL-UCS and propose techniques for recovery and reuse of chemicals formaldehyde, glutaraldehyde and xylenes, minimizing the impacts generated by the use, often indispensable and sometimes questionable, of such waste. So far two sets of samples were collected (in March and April 2013 of xylene, glutaraldehyde and formaldehyde in the GH and also at the AL-UCS and it is intended to repeat the collections with monthly periodicity, in the next two semesters. Partial results show that, comparing the relationship of area and the medium areas of the chromatographic (in µV.s of patterns with compounds of interest, an increase in the percentage of formaldehyde relative to the samples in standard formalin (121.84% may be due to contamination with organic compounds with a retention time close to the compound of interest, the xylene was little degradation in the samples, indicating that this compound can be reused in the common procedures of healthcare institutions, with respect to glutaraldehyde significant degradation was observed for the compound in samples represents only 61.88% of the chromatographic peak area of the standard, therefore the reuse of these compounds may require the use of purification methods such as simple distillation and fractional distillation

  5. Industry, university and government partnership to address research, education and human resource challenges for nuclear industry in Canada

    International Nuclear Information System (INIS)

    Mathur, R.M.

    2004-01-01

    Technology. Each of the above six NSERC-UNENE Industrial Research Chairs are tenured positions, funded at 2.0 M dollars or more for first five years. The Chairs may be subsequently renewed. A large number of graduate students are already enrolled with Professors Holt, Jiang and Pandey. In anticipation of receiving Ontario Council of Graduate Studies accreditation for the course-based M. Eng. Degree in Nuclear Engineering, the following courses have already been offered to a typical class of 20 students: Reactor Physics; Nuclear Plant Systems and Operations; Nuclear Reactor Safety Design; Thermal Hydraulics. In addition to these, courses to be offered in near future include: Engineering Risk Analysis; Reactor Chemistry and Corrosion; Nuclear Materials; Control, Instrumentation and Electrical Power Systems; Nuclear Waste Management; Fuel Management; Health Physics/Radiation Protection; Power Plant Thermodynamics; Codes, Standards and Jurisdictions; and Business Management. M.Eng. Courses are delivered in flexible format to suit distant faculty and part-time students. UNENE, an industry driven partnership of nuclear industry, universities and governments, created to address the future challenge of research, education and human resources in Canada, has made an impressive start. (author)

  6. Effect of Brain Drain (Human Capital Flight of Librarians on Service Delivery in Some Selected Nigerian Universities

    Directory of Open Access Journals (Sweden)

    Clara Chinyere Okoro

    2014-06-01

    Full Text Available This study seeks to describe and analyze the challenges occasioned by brain drain or human capital flight of librarians on service delivery in Nigerian Universities. The research adopted a descriptive survey design. A purposive sampling technique was used to select two geopolitical zones (South-South and South-West from the six geopolitical zones of Nigeria. Total enumeration was used because the population under study was considered appropriate for the research. The instrument used for data collection was questionnaire. Sixty copies of the instrument were distributed to 60 librarians in the two selected geopolitical zones. Copies of all the questionnaires were completed, retrieved, and found usable, thus giving a response rate of 100%. Survey results indicated that 315 librarians emigrated to foreign lands for various reasons, including unstable academic calendar and prospects for further training among others. This loss of personnel in the university libraries has a negative impact on service delivery as qualified information professionals and Information and Communication Technology (ICT experts are limited to mentor the younger professionals. Shift duties in academic libraries are also scaled down for lack of manpower. Based on the findings, the researchers recommend that the Federal Government of Nigeria should, as a matter of urgency, robustly fund tertiary education to enhance productivity. As they do this, the National Universities Commission (NUC is to empower academic libraries by ensuring that the staff development policy is strictly adhered to. This will translate into self-enhancement for staff, positive job attitude, and retention of professionals in the system.

  7. KNOWLEDGE AND ATTITUDE TOWARDS HUMAN PAPILLOMA VIRUS AND ITS VACCINE AMONG PHARMACY STUDENTS OF TERTIARY TEACHING UNIVERSITY HOSPITAL IN SOUTH INDIA

    OpenAIRE

    Raghupathi Mahitha; T. S. Arunprasath

    2016-01-01

    BACKGROUND Cervical cancer in women can be effectively prevented by HPV vaccine. Healthcare professionals including pharmacists have a role in creating awareness about this vaccine to public. In this context, it was decided to study awareness level about HPV among pharmacy students. The aim of the study is to study the knowledge and attitude towards human papilloma virus and it’s vaccine among pharmacy students of tertiary teaching university hospital in South India. MATERIA...

  8. Seroprevalence of human papillomavirus immunoglobulin G antibodies among women presenting at the reproductive health clinic of a university teaching hospital in Nigeria

    Directory of Open Access Journals (Sweden)

    Aminu M

    2014-05-01

    Full Text Available M Aminu,1 JZ Gwafan,1 HI Inabo,1 AO Oguntayo,2 EE Ella,1 AK Koledade21Department of Microbiology, Faculty of Science, Ahmadu Bello University, 2Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, NigeriaBackground: Human papillomavirus (HPV is the cause of 90%–95% of squamous cell cancers. Persistent infection with high-risk HPV can lead to development of precancerous lesions of the cervix in 5%–10% of infected women, and can progress to invasive cervical cancer 15–20 years later. This study was conducted to determine the seroprevalence of HPV immunoglobulin G (IgG antibodies among women of reproductive age attending a reproductive health clinic at Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.Methods: The study was descriptive, cross-sectional, and experimental, combining the use of a structured questionnaire and analysis of serum samples obtained from 350 consecutive consenting women. The serum samples were analyzed for IgG antibodies to HPV by enzyme-linked immunosorbent assay.Results: We found a seroprevalence of 42.9% (150/350 for IgG antibodies to HPV in these women. Women aged 45–49 years and those who had their sexual debut aged 20–23 years had the highest HPV seroprevalence, ie, 50% (57/114 and 51.1% (46/90, respectively. Presence of antibodies varied according to sociodemographic factors, but was significantly associated with educational status, tribe, and religion (P<0.05. Human papillomavirus infection was not significantly associated with the reproductive characteristics and sexual behavior of the women. Antibodies to HPV were detected in 50.0% (9/18 of women with a family history of cervical cancer and in 30.8% (4/13 of those with a history or signs of WHIM (warts, hypogammaglobulinemia, immunodeficiency, myelokathexis syndrome as a genetic disorder (P>0.05.Conclusion: Further studies are needed to determine the HPV serotypes and evaluate the risk of natural development

  9. 75 FR 33329 - Notice of Inventory Completion: New York University College of Dentistry, New York, NY

    Science.gov (United States)

    2010-06-11

    ... University College of Dentistry, New York, NY AGENCY: National Park Service, Interior. ACTION: Notice. Notice... the New York University College of Dentistry, New York, NY. The human remains were removed from.... A detailed assessment of the human remains was made by the New York University College of Dentistry...

  10. University course timetabling and the requirements: Survey in several universities in the east-coast of Malaysia

    Science.gov (United States)

    Aziz, Nurul Liyana Abdul; Aizam, Nur Aidya Hanum

    2017-08-01

    Course timetabling problem receives the highlight at the beginning of every semester. The problem is mainly on assigning courses to timeslot, rooms and lecturers which involving a set of rules and policies constraints. Generally, researchers present different features to signify their own universities' timetable according to the structure and behavior of their institution. However, the gap between theory and real-world applications that can be seen in the resulted timetable is the lacking of acknowledging human preferences. As to overcome this, it is very important to consider all the demands and preferences from timetabling community. This research therefore tries to accommodate the problem by investigating through surveys to several universities in the east coast of Malaysia the demands and preferences of individuals involved directly. Results from the questionnaires will be analyzed by using SPSS and all current issues regarding the demands will be included into our existing general university course timetabling mathematical model. The new university course timetabling mathematical model could best represent universities and be useful, especially in universities in Malaysia.

  11. Perceptions of the Veterinary Profession among Human Health Care Students before an Inter-Professional Education Course at Midwestern University.

    Science.gov (United States)

    Englar, Ryane E; Show-Ridgway, Alyssa; Noah, Donald L; Appelt, Erin; Kosinski, Ross

    2017-11-03

    Conflicts among health care professionals often stem from misperceptions about each profession's role in the health care industry. These divisive tendencies impede progress in multidisciplinary collaborations to improve human, animal, and environmental health. Inter-professional education (IPE) may repair rifts between health care professions by encouraging students to share their professional identities with colleagues in unrelated health care disciplines. An online survey was conducted at Midwestern University (MWU) to identify baseline perceptions about veterinary medicine among entry-level human health care students before their enrollment in an inter-professional course. Participation was anonymous and voluntary. The survey included Likert-type scales and free-text questions. Survey participants expressed their interest in and respect for the discipline of veterinary medicine, but indicated that their unfamiliarity with the profession hindered their ability to collaborate. Twenty percent of human health care students did not know the length of a Doctor of Veterinary Medicine (DVM) program and 27.6% were unaware that veterinarians could specialize. Although 83.2% of participants agreed that maintaining the human-animal bond is a central role of the veterinary profession, veterinary contributions to stem cell research, food and water safety, public health, environmental conservation, and the military were infrequently recognized. If IPE is to successfully pave the way for multidisciplinary collaboration, it needs to address these gaps in knowledge and broaden the definition of veterinary practice for future human health care providers.

  12. Black Holes in Our Universe

    Indian Academy of Sciences (India)

    are humanity's high-technology windows onto the universe. For reasons that will ... instrument ever built; and it was the first direct ... gravity will drive it to collapse into a black hole. Indeed, in 2007, ... Given their large X-ray power, it has been ...

  13. University of Maryland MRSEC - Leadership

    Science.gov (United States)

    . University of Maryland Materials Research Science and Engineering Center Home About Us Leadership MRSEC Templates Opportunities Search Home » About Us » Leadership Leadership Reutt-Robey photo Janice from the College of Arts and Humanities at UMD. Historical Leadership Ellen Williams MRSEC Director

  14. Women, University and Science in Twentieth-Century Spain

    Science.gov (United States)

    Canales, Antonio Fco.

    2018-01-01

    This article aims to question the widely accepted idea that female university students in Spain have, in the past, tended to opt for degrees in the field of humanities. Based on an analysis of the official statistics that are currently available, the paper demonstrates that Spanish female university students showed a clear preference for…

  15. The Localization Characteristic of the Idea and Mission of Private Universities in China

    Directory of Open Access Journals (Sweden)

    Fan Jixuan

    2013-12-01

    Full Text Available The idea and mission of college and university are always assuming a fluxion accompanied with social upheaval. The Chinese private universities' idea and mission take on local characteristic: “As the foundation of a nation, education should meet the needs of social development, should take the responsibility of practical application and take service for the community”, “Education should place people first, attach great importance to the improvement of the students' individual quality and put heavy emphasis on the service quality”, which have become the important content of the faith of Chinese private universities; “To strengthen the internationalization and to open running college”, which is the new direction of faith of Chinese private universities. It became those private universities’ bounden duty to translate normal human resources into quality human capital. So, those private universities have the responsibilities and missions to construct human resources powerful nation, to popular higher education with high standard satisfied by people.

  16. Universities' Role in Regional Development: A Case Study of University for Development Studies, Ghana

    Science.gov (United States)

    Abonyi, Usman Kojo

    2016-01-01

    This study, employing an interpretive research paradigm, sought to investigate into how University for Development Studies (UDS) is responding to its regional development mandate with a specific focus on how it is responding to human capital development, innovation capabilities, and social and environmental development in northern Ghana. A study…

  17. Assessing the universal health coverage target in the Sustainable Development Goals from a human rights perspective.

    Science.gov (United States)

    Chapman, Audrey R

    2016-12-15

    The UN's Sustainable Development Goals (SDGs), adopted in September 2015, include a comprehensive health goal, "to ensure healthy lives and promote well-being at all ages." The health goal (SDG 3) has nine substantive targets and four additional targets which are identified as a means of implementation. One of these commitments, to achieve universal health coverage (UHC), has been acknowledged as central to the achievement of all of the other health targets. As defined in the SDGs, UHC includes financial risk protection, access to quality essential health-care services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. This article evaluates the extent to which the UHC target in the SDGs conforms with the requirements of the right to health enumerated in the International Covenant on Economic, Social and Cultural Rights, the Convention on the Rights of the Child, and other international human rights instruments and interpreted by international human rights bodies. It does so as a means to identify strengths and weaknesses in the framing of the UHC target that are likely to affect its implementation. While UHC as defined in the SDGs overlaps with human rights standards, there are important human rights omissions that will likely weaken the implementation and reduce the potential benefits of the UHC target. The most important of these is the failure to confer priority to providing access to health services to poor and disadvantaged communities in the process of expanding health coverage and in determining which health services to provide. Unless the furthest behind are given priority and strategies adopted to secure their participation in the development of national health plans, the SDGs, like the MDGs, are likely to leave the most disadvantaged and vulnerable communities behind.

  18. Nursing challenges for universal health coverage: a systematic review

    Directory of Open Access Journals (Sweden)

    Mariana Cabral Schveitzer

    2016-01-01

    Full Text Available Objectives to identify nursing challenges for universal health coverage, based on the findings of a systematic review focused on the health workforce' understanding of the role of humanization practices in Primary Health Care. Method systematic review and meta-synthesis, from the following information sources: PubMed, CINAHL, Scielo, Web of Science, PsycInfo, SCOPUS, DEDALUS and Proquest, using the keyword Primary Health Care associated, separately, with the following keywords: humanization of assistance, holistic care/health, patient centred care, user embracement, personal autonomy, holism, attitude of health personnel. Results thirty studies between 1999-2011. Primary Health Care work processes are complex and present difficulties for conducting integrative care, especially for nursing, but humanizing practices have showed an important role towards the development of positive work environments, quality of care and people-centered care by promoting access and universal health coverage. Conclusions nursing challenges for universal health coverage are related to education and training, to better working conditions and clear definition of nursing role in primary health care. It is necessary to overcome difficulties such as fragmented concepts of health and care and invest in multidisciplinary teamwork, community empowerment, professional-patient bond, user embracement, soft technologies, to promote quality of life, holistic care and universal health coverage.

  19. Efficient coding explains the universal law of generalization in human perception.

    Science.gov (United States)

    Sims, Chris R

    2018-05-11

    Perceptual generalization and discrimination are fundamental cognitive abilities. For example, if a bird eats a poisonous butterfly, it will learn to avoid preying on that species again by generalizing its past experience to new perceptual stimuli. In cognitive science, the "universal law of generalization" seeks to explain this ability and states that generalization between stimuli will follow an exponential function of their distance in "psychological space." Here, I challenge existing theoretical explanations for the universal law and offer an alternative account based on the principle of efficient coding. I show that the universal law emerges inevitably from any information processing system (whether biological or artificial) that minimizes the cost of perceptual error subject to constraints on the ability to process or transmit information. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  20. Collaborative Thinking: The Challenge of the Modern University

    Science.gov (United States)

    Corrigan, Kevin

    2012-01-01

    More collaborative work in the humanities could be instrumental in helping to break down the traditional rigid boundaries between academic divisions and disciplines in modern universities. The value of the traditional model of the solitary humanities scholar or the collaborative science paradigm should not be discounted. However, increasing the…

  1. COPD depicted – patients drawing their lungs

    Directory of Open Access Journals (Sweden)

    Kaptein AA

    2017-11-01

    Full Text Available Ad A Kaptein,1 Jitske Tiemensma,2 Elizabeth Broadbent,3 Guus M Asijee,4,5 Maarten Voorhaar4,5 1Medical Psychology, Leiden University Medical Centre (LUMC, Leiden, the Netherlands; 2Psychological Sciences, University of California, Merced, CA, USA; 3Psychology Department, Auckland University Medical School, Auckland, New Zealand; 4CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, the Netherlands; 5Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany Background: Given the increasing importance of patient-reported outcomes (PRO in quality medical care, we examined the value and feasibility of an innovative method for assessing patients’ illness perceptions, represented in drawings made by patients with COPD of their lungs. Aim: The aim of our study was: to study patients’ representation of COPD as reflected in their drawings of their lungs; and to examine scores on a validated measure that assesses illness perceptions (ie, Brief Illness Perception Questionnaire [B-IPQ]. Patients and methods: One hundred outpatients with COPD, mean age 70 years, selected from a pharmacy database, participated and 98 filled out the B-IPQ. Eighty-seven patients completed the drawing task. Results: The illness perceptions as reflected in the responses to the B-IPQ scales represented a quite optimistic view of COPD and its consequences. The drawings of the lungs reflected a considerable discordance between patients’ representations and medically accepted representations of lungs of a person with COPD. Conclusion: Assessing illness perceptions in clinical care and research about COPD offers opportunities to identify goals for patient education and self-management. Inviting patients to draw their illness is an innovative and promising approach to assessing PRO. Keywords: COPD, drawings, illness perceptions, PRO, quality of life, self-management

  2. Human decomposition and the reliability of a 'Universal' model for post mortem interval estimations.

    Science.gov (United States)

    Cockle, Diane L; Bell, Lynne S

    2015-08-01

    one region to any other region. These results also suggest that there are other variables, apart from temperature and humidity that may impact the rate of human decomposition. These variables, or complex of variables, are considered regionally specific. Neither of the Universal Formulae performed well, and our results do not support the proposition of Universality for PMI estimation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. Prof. Dr. Hilbrand Boschma 22 April 1893 - 22 July 1976 : Obituary and bibliography

    NARCIS (Netherlands)

    Vervoort, W.

    1977-01-01

    Hilbrand Boschma, professor emeritus of systematic zoology and former director of the Rijksmuseum van Natuurlijke Historie (National Museum of Natural History), Leiden, Netherlands, passed away on 22 July, 1976, in Leiden at the age of 83. Born of peasant stock in IJsbrechtum, Wymbritseradeel, in

  4. 77 FR 34987 - Notice of Inventory Completion: University of Pennsylvania Museum of Archaeology & Anthropology...

    Science.gov (United States)

    2012-06-12

    ... Inventory Completion: University of Pennsylvania Museum of Archaeology & Anthropology, University of... of Pennsylvania Museum of Archaeology & Anthropology has completed an inventory of human remains in..., University of Pennsylvania Museum of Archaeology & Anthropology, University of Pennsylvania, 3260 South...

  5. The corpus-driven revolution in Polish Sign Language: the interview with Dr. Paweł Rutkowski

    Directory of Open Access Journals (Sweden)

    Iztok Kosem

    2018-02-01

    Full Text Available Dr. Paweł Rutkowski is head of the Section for Sign Linguistics at the University of Warsaw. He is a general linguist and a specialist in the field of syntax of natural languages, carrying out research on Polish Sign Language (polski język migowy — PJM. He has been awarded a number of prizes, grants and scholarships by such institutions as the Foundation for Polish Science, Polish Ministry of Science and Higher Education, National Science Centre, Poland, Polish–U.S. Fulbright Commission, Kosciuszko Foundation and DAAD. Dr. Rutkowski leads the team developing the Corpus of Polish Sign Language and the Corpus-based Dictionary of Polish Sign Language, the first dictionary of this language prepared in compliance with modern lexicographical standards. The dictionary is an open-access publication, available freely at the following address: http://www.slownikpjm.uw.edu.pl/en/. This interview took place at eLex 2017, a biennial conference on electronic lexicography, where Dr. Rutkowski was awarded the Adam Kilgarriff Prize and gave a keynote address entitled Sign language as a challenge to electronic lexicography: The Corpus-based Dictionary of Polish Sign Language and beyond. The interview was conducted by Dr. Victoria Nyst from Leiden University, Faculty of Humanities, and Dr. Iztok Kosem from the University of Ljubljana, Faculty of Arts.

  6. Attitudes of University of Botswana Faculty of Humanities students ...

    African Journals Online (AJOL)

    We administered a questionnaire to undergraduate students at the University of Botswana to find out the languages the students speak, and their attitudes towards minority languages spoken in their country as well as to determine what their views were towards including the said languages in the curriculum. We found out ...

  7. Cultural pathways through universal development.

    Science.gov (United States)

    Greenfield, Patricia M; Keller, Heidi; Fuligni, Andrew; Maynard, Ashley

    2003-01-01

    We focus our review on three universal tasks of human development: relationship formation, knowledge acquisition, and the balance between autonomy and relatedness at adolescence. We present evidence that each task can be addressed through two deeply different cultural pathways through development: the pathways of independence and interdependence. Whereas core theories in developmental psychology are universalistic in their intentions, they in fact presuppose the independent pathway of development. Because the independent pathway is therefore well-known in psychology, we focus a large part of our review on empirically documenting the alternative, interdependent pathway for each developmental task. We also present three theoretical approaches to culture and development: the ecocultural, the sociohistorical, and the cultural values approach. We argue that an understanding of cultural pathways through human development requires all three approaches. We review evidence linking values (cultural values approach), ecological conditions (ecocultural approach), and socialization practices (sociohistorical approach) to cultural pathways through universal developmental tasks.

  8. Philanthropy and Human Rights

    DEFF Research Database (Denmark)

    Larsen, Øjvind

    2013-01-01

    written about philanthropy from a political, sociological, anthropological and managerial perspective. However, an essential question remains: what does philanthropy mean? In a Greek context, philanthropy is connected to a friendly act towards one’s owns close connections such as family or fellow citizens......, and normally utilized to promote one’s own prestige in the city-state. In Roman context, universal humanism, humanitas, was invented. This universal perspective was also supported by Christianity. It is this universal concept of philanthropy which is the foundation for the different philanthropic traditions...... in Germany, England, France and USA. In each tradition is developed special features of the concept of philanthropy. The four traditions are summarized in the UN universal human rights, which has become the common normative reference for global philanthropy. In this way philanthropy has become, in a modern...

  9. The quantum universe: philosophical foundations and oriental medicine.

    Science.gov (United States)

    Kafatos, Menas C; Yang, Keun-Hang

    2016-12-01

    The existence of universal principles in both science and medicine implies that one can explore their common applicability. Here we explore what we have learned from quantum mechanics, phenomena such as entanglement and nonlocality, the role of participation of the observer, and how these may apply to oriental medicine. The universal principles of integrated polarity, recursion, and creative interactivity apply to all levels of existence and all human activities, including healing and medicine. This review examines the possibility that what we have learned from quantum mechanics may provide clues to better understand the operational principles of oriental medicine in an integrated way. Common to both is the assertion that Consciousness is at the foundation of the universe and the inner core of all human beings. This view goes beyond both science and medicine and has strong philosophical foundations in Western philosophy as well as monistic systems of the East.

  10. Historical Theology at public universities matter

    Directory of Open Access Journals (Sweden)

    Jerry Pillay

    2017-11-01

    Full Text Available South African universities are in the process of serious transformation and restructuring. The place of faculties of theology at universities has come under the spotlight resulting in the closure of several theological faculties or in the moving of theology to other faculties, mainly humanities or arts. Theology is under pressure and in the current academic environment, Church History, in its traditional form, has all but disappeared from South African universities.  This article is an attempt to address the current situation. Whilst this article looks at the issue of theology at public universities, its main focus is to explore the future study of church history in the context of universities and, in particular, a Faculty of Theology. Understanding church history in the broad framework as Historical Theology, this article asserts the significance of church history at public universities, but points out the need to restructure the Department giving due consideration to community engagement, internationalisation, transformation, africanisation and interreligious collaboration. All of these would have a serious impact on teaching, learning and research.

  11. Unequal Access to Universities in a Country with High Social Equality

    DEFF Research Database (Denmark)

    Munk, Martin D.; Baklanov, Nikita

    likely to choose gymnasium. The results also show a social gradient at the university level with males being more likely to become a graduate student. The choice of elite university is even more exclusive since especially students with relatively wealthy, highly educated parents, and mothers...... with a professional background have a higher chance of entering. Social selection is increasing at a lower level of strength. Our model 2 shows that students from families with higher levels of income are more likely to choose health sciences, social and natural sciences than the humanities. Also individuals...... with university educated fathers and mothers are more likely to choose health sciences than the humanities. Males are more likely than females to choose social and natural sciences than the humanities and health sciences. In addition, our model 3 shows that selection into health sciences is very clear. Mothers...

  12. Human Identities and Nation Building: Comparative Analysis, Markets, and the Modern University

    Science.gov (United States)

    Callejo Pérez, David; Hernández Ulloa, Abel; Martínez Ruiz, Xicoténcatl

    2014-01-01

    The purpose of this article is to discuss the dilemma of the multi-university in sustainable education, research, and outreach by addressing some of the ways in which universities, must generate actions that seek to address these challenges, develop strategic relationships, and maximize their potential in the areas of teaching, research and…

  13. 75 FR 8742 - Notice of Inventory Completion: Stephen F. Austin State University, Nacogdoches, TX

    Science.gov (United States)

    2010-02-25

    ... DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Stephen F. Austin... control of Stephen F. Austin State University, Nacogdoches, TX. The human remains and associated funerary..., which was under contract with Stephen F. Austin State University. In the early 1900s, human remains...

  14. Cultural universals: So what?

    Directory of Open Access Journals (Sweden)

    M. Elaine Botha

    1989-03-01

    Full Text Available The search for the elusive "cultural universal s” in a variety of academic disciplines has been motivated b y the spectre of relativism in its diverse guises. The problem of relativism has been thrust upon us inter alia by the inability of our epistemological models to account for social and cultural, moral and cognitive diversity and to provide us with criteria by means of which to judge aberrations like ideologies. Contrary to the general trend I would like to argue that it is not the spectre of relativism in its various guises which necessitates the search for cultural universals, nor is this the only motivation for a Christian to argue in favour of the recognition of cultural universals. Various authors have suggested that such universal structures do exist; that they condition human and societal behaviour and that it would in principle be possible to construct a theory of these structural universals or a "biogrammar" or "geography ” of the universal cultural acquisition device of humankind (cf. Harre,1976, 32; Johnson, 1987: xxxvii ; Tige r and Fox, 1974:17,30. Cross -cu ltural research in both psychology and anthropology has pointed to the existence of such traits, and in recent philosophical discussions Apel and others have pointed to the necessity of recognizing the existence of some sort of " transcendentalia" . These arguments emphasize elements that are common to diverse approaches to the problem of cultural universals. Christian scholars could accept most of these arguments as valid and yet argue in favour of a very specifically modified version of the notion of cultural universals. This essay attempts to develop such a position.

  15. Use of transgenic mice in lipoprotein metabolism and atherosclerosis research

    NARCIS (Netherlands)

    Havekes, L.M.; Vlijmen, B.J.M. van; Jong, M.C.; Dijk, K.W. van; Hofker, M.H.

    1997-01-01

    In APOE*3-Leiden transgenic mice the atherosclerotic lesion size is correlated with plasma cholesterol. In these mice the plasma lipid levels are positively correlated with the relative amount of APOE 3-Leiden protein on the VLDL particle. The plasma cholesterol levels are influenced by diet, age

  16. 77 FR 11582 - Notice of Inventory Completion: Central Washington University Department of Anthropology...

    Science.gov (United States)

    2012-02-27

    ...: Central Washington University Department of Anthropology, Ellensburg, WA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Central Washington University Department of Anthropology has... Central Washington University Department of Anthropology. Repatriation of the human remains and associated...

  17. Book Reviews

    Directory of Open Access Journals (Sweden)

    Hans Antlöv

    1996-04-01

    Full Text Available - R. Anderson Sutton, Wim van Zanten, Ethnomusicology in the Netherlands: present situation and traces of the past. Leiden: Centre of Non-Western Studies, Leiden University, 1995, ix + 330 pp. [Oideion; The performing arts worldwide 2. Special Issue]., Marjolijn van Roon (eds. - T.E. Behrend, Willem Remmelink, The Chinese War and the collapse of the Javanese state, 1725-1743. Leiden: KITLV Press, 1994, 297 pp. [Verhandelingen 162]. - Erik Brandt, Eric Venbrux, A death in the Tiwi Islands; Conflict, ritual and social life in an Australian Aboriginal Community. Cambridge: Cambridge University Press, 1995, xvii + 269 pp. - Madelon Djajadiningrat-Nieuwenhuis, Tineke Hellwig, In the shadow of change; Images of women in Indonesian literature. Berkeley: University of California, Centers for South and Southeast Asia Studies, 1994, xiii + 259 pp. [Monograph 35]. - M. Estellie Smith, Peter J.M. Nas, Issues in urban development; Case studies from Indonesia. Leiden: Research School CNWS, 1995, 293 pp. [CNWS Publications 33]. - Uta Gärtner, Jan Becka, Historical dictionary of Myanmar. Metuchen, N.J.: Scarecrow Press, xxii + 328 pp. [Asian Historical Dictionaries 15]. - Beatriz van der Goes, H. Slaats, Wilhelm Middendorp over de Karo Batak, 1914-1919. Deel 1. Nijmegen: Katholieke Universiteit, Faculteit der Rechtsgeleerdheid, 1994, xvii + 313 pp. [Reeks Recht en Samenleving 11]., K. Portier (eds. - Stephen C. Headley, Janet Carsten, About the house, Lévi-Strauss and beyond. Cambridge: Cambridge University Press, 1995, xiv + 300 pp., Stephen Hugh-Jones (eds. - Stephen C. Headley, James J. Fox, Inside Austronesian houses; Perspectives on domestic designs for living. Canberra: Department of Anthropology, Research School of Pacific Studies, The Australian National University, 1993, x + 237 pp. - M. Hekker, Helmut Buchholt, Continuity, change and aspirations; Social and cultural life in Minahasa, Indonesia. Singapore: Institute of Southeast Asian Studies, 1994

  18. Probing cosmic velocity flows in the local universe

    NARCIS (Netherlands)

    Romano Díaz, Emilio

    2004-01-01

    Probably from even before the dawn of civilization humans have been gazing at the starry nights and wondered about the world in which they found themselves living. Questions that have occupied humanity were ones like “How did the universe begin?” “How had everything come into being?”. Zie: Summary

  19. Women and culture. The case for universal rights.

    Science.gov (United States)

    Ruether, R R

    1996-01-01

    As the movement for women's human rights has become globalized, the charge that feminism is a form of Western cultural imperialism has emerged. An African Anglican priest used this as a response to the author's lecture on Christian feminism and added that "you can't challenge culture." The author responded that since racism could be considered a part of traditional White culture, does this mean that racism can't be challenged. The priest's argument is a common one used by Third World men, Third World women, and First World men to denounce the concept of human rights as women's rights. The Vatican used this argument during recent international conferences to oppose such things as the international approval of family planning and safe abortion, the diversity of notions of family, and an acknowledgement of homosexuality. In UN forums, Islamic nations also argue against women's rights and against the universalization of human rights, which they feel are properly superseded by local cultures. These concepts translated into debates at the Fourth World Conference on Women on topics such as conflicts between religious laws and women's inheritance rights. The culture-human rights argument is also used to defend the practice of female genital mutilation, which is used to control female sexuality in some traditional societies. Western feminist theory must guard against postmodernist critiques of modernity in the name of cultural diversity, since such critiques can make women vulnerable to right-wing male exploitation under premodern patriarchal norms. Classical philosophies of natural law, on the other hand, assume that the cosmos is a whole and that its nature implies ethical norms which govern human well-being. In this tradition, culture is a particular version of the common whole and must constantly be tested against discernment of the universals of human nature in order to be corrected. Feminists must temper their zeal for cultural diversity with an underlying acceptance

  20. Interdisciplinarity and transdisciplinarity: prospects for the design the university to come

    Directory of Open Access Journals (Sweden)

    José Acosta

    2016-12-01

    Full Text Available The present work presents some reflections on the current situation of the university as a social institution of high studies; particularly in the fact that it has emphasized in the disciplinary approach leading to the fragmentation of knowledge, the little link between the institution and its social context, among others. This situation represents an obstacle to achieve a true transformation in the university context. Based on the above, the methodological approach was guided by hermeneutics, which, as a critical and reflexive exercise, allowed to establish a state of the art on the theoretical treatment that has been given to the subject which contributed with the proposal of a series of reflections in Around the perspectives that will allow to dynamize the educational process in the university to come, which is the purpose of this investigation. Reason why, interdisciplinary is proposed as a way to achieve transdisciplinarity as referents that contribute to the conception of the university to come, from wich science,technology and humanism are assumed to contribute to the strengthening of human values And the social capital of the region, through a training that integrates university knowledge with the plurality of cultural, daily and historical knowledge to assist in the construction of a more humane society. 

  1. 77 FR 15802 - Notice of Inventory Completion: Central Washington University Department of Anthropology...

    Science.gov (United States)

    2012-03-16

    ...: Central Washington University Department of Anthropology, Ellensburg, WA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Central Washington University Department of Anthropology has... contact the Central Washington University Department of Anthropology. Repatriation of the human remains to...

  2. 76 FR 36149 - Notice of Inventory Completion: Western Michigan University, Department of Anthropology...

    Science.gov (United States)

    2011-06-21

    ...: Western Michigan University, Department of Anthropology, Kalamazoo, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: Western Michigan University, Department of Anthropology, has completed... contact the Western Michigan University, Department of Anthropology. Disposition of the human remains and...

  3. Urban Environment Development based on Universal Design Principles

    Science.gov (United States)

    Harsritanto, Bangun Ir

    2018-02-01

    Universal Design is a design which facilitated full range of human diversity. By applying Universal design principles, urban environment can be more functional and more user-friendly for everyone. This study examined five urban streets of South Korea as a country experienced on developing various urban street designs based on universal design. This study aimed to examine and compare the South Korea cases using seven principles of universal design. The research methods of this study are literature study, case study, and site observation. The results of this study are: South Korea cases are good practices, urgency of implementing the direction into local regulations; and change of urban development paradigm.

  4. Pathways from College to University: A Social Science Example from Ontario

    Science.gov (United States)

    LeSage, Ann; Samis, John; Hinch, Ron; Longo, Fabiola; DiGiuseppe, Maurice; Goodman, William; Percival, Jennifer; De La Rocha, Arlene; Rodrigues, Anna; Raby, Phil; Sanchez, Otto

    2014-01-01

    This study evaluates the impact of a College to University Pathway Program in the Faculty of Social Science and Humanities at The University of Ontario Institute of Technology. The findings support the assertion that Pathway students perform as well as or better than students who enter university directly from secondary school. This finding is…

  5. Knowledge, attitudes, and perception towards human papillomavirus among university students in Pakistan.

    Science.gov (United States)

    Khan, Tahir Mehmood; Buksh, Malik Allah; Rehman, Inayat Ur; Saleem, Ahsan

    2016-12-01

    This cross-sectional study comprises a questionnaire-based survey regarding knowledge about human papillomavirus and its vaccine among students in different educational fields at public and private universities in the city of Lahore in Pakistan. A 26-item questionnaire was used to attain the objective of this study. The reliability of this tool was assessed using Cronbach's alpha (0.79) and the Kaiser-Meyer-Olkin value was 0.827. The response rate to the survey was 78.0%, of whom the majority (74.9%) were females and 308 (79%) were single (median age=23 years). While assessing the respondents' knowledge about HPV, 223(57%) students reported that they had already heard of HPV (human papillomavirus) and nearly 215 (55%) reported that HPV causes cervical cancer and can infect both men and women. Gender and field of study were two main factors found influencing the respondents' knowledge about HPV. Moreover, students' understanding about the mode of transmission of HPV was cursory: 40.51% said they did not know how HPV is transmitted, 133 (34.10%) stated that HPV spreads through the exchange of bodily fluids, and 22 (5.64%) selected cough/sneezing. In terms of prevention, 175 (44.87%) students stated that HPV can be prevented by vaccination, 30.0% reported sexual abstinence, 21.54% using condoms, and nearly 5.38% disclosed use of antibiotics. Addressing the knowledge of students regarding HPV vaccine, nearly 53% stated there is no vaccine against HPV and almost 64% rejected the statement that HPV vaccine prevents cervical cancer. In addition, students reported that they will be more than willing to get vaccinated for HPV if their physician recommend them (RII=0.74) followed by parents (RII=0.69). The results of this study revealed a poor understanding among respondents about the health problems associated with HPV, its prevention, modes of transmission and arability of HPV vaccine in Pakistan. Copyright © 2016. Published by Elsevier B.V.

  6. 78 FR 5200 - Notice of Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA

    Science.gov (United States)

    2013-01-24

    ... Inventory Completion: University of Washington, Department of Anthropology, Seattle, WA AGENCY: National... Anthropology, has completed an inventory of human remains and associated funerary objects, in consultation with... acting on behalf of the University of Washington, Department of Anthropology. Disposition of the human...

  7. Wits University's response to HIV/AIDS: flagship programme or ...

    African Journals Online (AJOL)

    HIV/AIDS is a threat to the creation of human capital and development prospects in southern Africa and South Africa. The University of the Witwatersrand (Wits) is a well-regarded institution of higher education in Johannesburg. This paper outlines the university's qualified failure to implement its HIV/AIDS Policy through a ...

  8. [On the first studies of electrophysiology].

    Science.gov (United States)

    de Micheli, Alfredo

    2011-01-01

    A historical outline of the evolution of electrophysiology from the eighteenth century is shortly presented. Topics concerning the so called animal electricity starting from the observations on descharges of Torpedo fish until Bolognese Galvani's researches on the frogs are exposed. The points of view of their oppositionists also are examined. These ones, leaded by the physicist Alessandro Volta, professor in the University of Pavia, believed that electricity detected by galvanists was not inherent to animal but was due to the action of the metallic conductors present in the circuit: contact electricity. Only towards the middle of the nineteenth century the physicist Carlo Matteucci attained to demonstrate the existente of the real animal electricity in form of injury current. It was possible to determine that quantitatively thanks to the capillary electrometer built in 1872 by the French physicist Gabriel Lippmann. This instrument was used by the English physiologist Waller in order to obtain the primitive electrocardiographic tracings in humans (1887). At beginnings of the twentieth century, the Dutch professor Willem Einthoven, of the University of Leiden, introduced his string galvanometer which permitted to allow the modern electrocardiography. So it was possible to record the electrical potentials of myocardial cells, first in vitro, later in isolated and perfused heart, son after in dog's heart in situ and finally in human heart. Therefore now it is possible to effectuate endocardial and epicardial mappings, indispensable in order to diagnose and treat the cardiac arrhythmias.

  9. Prólogo arameo y anotaciones hebreas de Alfonso de Zamora para una copia manuscrita del Targum a los Profetas encargada por la Universidad de Salamanca

    Directory of Open Access Journals (Sweden)

    Fontela, Carlos Alonso

    2009-12-01

    Full Text Available University Library Ms. Or. 645, f. 110r (ol. Warner 65 F contains, besides a draft for an Aramaic prologue to the work on Targum written by Alonso de Zamora ca. 1532, additional notes written by himself dealing with the comission he received to copying Targumic texts. The present article improves the edition of the Aramaic prologue, previously published by Neubauer (1895, offering a Spanish translation and the edition of the marginal notes, that contain a draft of the prayers (תפלותופיהספדים for the partial colophons of the books of Ezekiel, Hosea and Joel’s Targums. These pa - tial colophons in the Leiden Ms. coincide with the clean drafts by Zamora preserved in an autograph manuscript, Salamanca University Library Ms. M-3 (Est.-1, Cajón I-Núm. 2. An explanation concerning additional annotations (the incipit of Isaiah 57, that spoiled the folio, and led it to its being re-used by Alonso de Zamora as a draft.

    El ms. Or. 645, f.º 110r (ol. Warner 65 F de la Leiden University Library, además del borrador de un prólogo arameo a la obra de Targum escrito por Alfonso de Zamora hacia el año 1532 por encargo de la Universidad de Salamanca, contiene otras anotaciones del mismo autor que aquí se publican por primera vez y que también formaban parte del mismo encargo de copia de textos targúmicos. En el presente artículo, además de mejorar el texto arameo del prólogo ya publicado por Neubauer en 1895, se ofrece su traducción española por primera vez. Asimismo, se publica y traduce una anotación marginal que consiste en un borrador de las jaculatorias o doxologías (תפלותופיהספדים para los colofones parciales de los libros del Targum de Ezequiel, Oseas y Joel. Estos colofones parciales del ms. de Leiden coinciden con los pasados a limpio que se conservan en el manuscrito autógrafo de Alfonso de Zamora ms. M-3 (Est.-1, Cajón I-Núm. 2 de la Biblioteca Universitaria de Salamanca. Se

  10. Unceratainty of Heisenberg in Universe Destruction

    Directory of Open Access Journals (Sweden)

    Sri Jumini

    2017-12-01

    Full Text Available The Qur'an is a guidence which explaines all about the universe to human being. The discovery of science has been able to explain the truth of the Qur'an scientifically. One of which is the principle of Heisenberg's uncertainty in the event of the universe destruction. The purpose of this research is to know: 1 Science's view of the event of the universe destruction (Big Crunch in Qur’an [Al Infithaar]: 1-3, and How the relation of Heisenberg’s uncertainty principles and the law of thermodynamics II toward  the collapse of the universe (Big Crunch based on Scientific views and the Quran. This research is a qualitative research using library research method which analyzes the related books directly or indirectly. The results of the analysis stated that: 1 The concentration of mass, which is big enough, relates to some of the laws of physics, those are: Relativity, Heisenberg's uncertainty principles, and the law of Thermodynamic II; 2 The universe will return at its sole point, i.e; the absence of the universe; 3 The destruction of the universe is the destruction of the order of the universe which then the stars fall scatteredly because of the gravitational force that prevents them disappears, the balance of the universe diminishes, decreases and becomes uncertain, and eventually disappears.

  11. A Human Rights Glossary.

    Science.gov (United States)

    Flowers, Nancy

    1998-01-01

    Presents a human rights glossary that includes definitions of basic terms, treaties, charters, and groups/organizations that have been featured in previous articles in this edition of "Update on Law-Related Education"; the human rights terms have been compiled as part of the celebration of the Universal Declaration of Human Rights…

  12. The Rijksherbarium, in past and present

    NARCIS (Netherlands)

    Kalkman, C.

    1979-01-01

    As is explained in other papers in this jubilee volume (v. Steenis – Kruseman, Smit) it was not on purpose, but by coincidence that the Rijksherbarium came to Leiden. However, Leiden will have been the obvious alternative after Brussels, for Fischer as well as for Von Siebold. There Reinwardt,

  13. On Compatibility Between University and Sustainability: Contentions, Opportunities, and Directions

    Directory of Open Access Journals (Sweden)

    Jung Hsiao

    2017-06-01

    Full Text Available The advocates of sustainability have started to regard universities as an important means to realize sustainable development since the Tbilisi Declaration in 1977, making universities a target of many initiatives to this day. However, as this study argues in accordance with the result of literature review, this phenomenon is politically correct as much as controversial. The reason lies in the fundamental question about the nature of university. In other words, the talk about how to realize the ideal of sustainable development through universities has to involve first the question of “what is the paradigm for universities?” As this study argues in light of rudimentary inquiries of the three paradigms and the reflection on educational philosophy, the university is better when it is based on the paradigm of “liberal education” rather than that of “knowledge factory” or “pragmatism.” The study suggests that universities should adhere to the paradigm of liberation education as the most appropriate response to the ideal of sustainable development. Not only so, this study further points out what universities can do on the basis of their roles in the society: a member in the society, a vocational education institution, a training center for future leaders, and an organization for humanity and knowledge. It is especially worth noting that universities have potentials and advantages for the development of humanities and environmental ethics that are yet to be discovered and expanded.

  14. Effect modification, interaction and mediation: an overview of theoretical insights for clinical investigators

    Directory of Open Access Journals (Sweden)

    Corraini P

    2017-06-01

    Full Text Available Priscila Corraini,1 Morten Olsen,1 Lars Pedersen,1 Olaf M Dekkers,1,2 Jan P Vandenbroucke1–3 1Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Leiden University Medical Center, Leiden, the Netherlands; 3Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK Abstract: We revisited the three interrelated epidemiological concepts of effect modification, interaction and mediation for clinical investigators and examined their applicability when using research databases. The standard methods that are available to assess interaction, effect modification and mediation are explained and exemplified. For each concept, we first give a simple “best-case” example from a randomized controlled trial, followed by a structurally similar example from an observational study using research databases. Our explanation of the examples is based on recent theoretical developments and insights in the context of large health care databases. Terminology is sometimes ambiguous for what constitutes effect modification and interaction. The strong assumptions underlying the assessment of interaction, and particularly mediation, require clinicians and epidemiologists to take extra care when conducting observational studies in the context of health care databases. These strong assumptions may limit the applicability of interaction and mediation assessments, at least until the biases and limitations of these assessments when using large research databases are clarified. Keywords: methods, epidemiology, effect modifiers, stratified analyses, health care administrative claims

  15. 77 FR 65403 - Notice of Inventory Completion: Maxwell Museum of Anthropology, University of New Mexico...

    Science.gov (United States)

    2012-10-26

    ... Inventory Completion: Maxwell Museum of Anthropology, University of New Mexico, Albuquerque, NM AGENCY... affiliated with the human remains may contact the Maxwell Museum of Anthropology. Repatriation of the human..., Maxwell Museum of Anthropology, MSC01 1050, University of New Mexico, Albuquerque, NM 87131-0001...

  16. 77 FR 65404 - Notice of Inventory Completion: Maxwell Museum of Anthropology, University of New Mexico...

    Science.gov (United States)

    2012-10-26

    ... Inventory Completion: Maxwell Museum of Anthropology, University of New Mexico, Albuquerque, NM; Correction... affiliated with the human remains may contact the Maxwell Museum of Anthropology. Repatriation of the human..., Maxwell Museum of Anthropology, MSC01 1050, University of New Mexico, Albuquerque, NM 87131-0001...

  17. Stochastic self-similar and fractal universe

    International Nuclear Information System (INIS)

    Iovane, G.; Laserra, E.; Tortoriello, F.S.

    2004-01-01

    The structures formation of the Universe appears as if it were a classically self-similar random process at all astrophysical scales. An agreement is demonstrated for the present hypotheses of segregation with a size of astrophysical structures by using a comparison between quantum quantities and astrophysical ones. We present the observed segregated Universe as the result of a fundamental self-similar law, which generalizes the Compton wavelength relation. It appears that the Universe has a memory of its quantum origin as suggested by R. Penrose with respect to quasi-crystal. A more accurate analysis shows that the present theory can be extended from the astrophysical to the nuclear scale by using generalized (stochastically) self-similar random process. This transition is connected to the relevant presence of the electromagnetic and nuclear interactions inside the matter. In this sense, the presented rule is correct from a subatomic scale to an astrophysical one. We discuss the near full agreement at organic cell scale and human scale too. Consequently the Universe, with its structures at all scales (atomic nucleus, organic cell, human, planet, solar system, galaxy, clusters of galaxy, super clusters of galaxy), could have a fundamental quantum reason. In conclusion, we analyze the spatial dimensions of the objects in the Universe as well as space-time dimensions. The result is that it seems we live in an El Naschie's E-infinity Cantorian space-time; so we must seriously start considering fractal geometry as the geometry of nature, a type of arena where the laws of physics appear at each scale in a self-similar way as advocated long ago by the Swedish school of astrophysics

  18. Human Rights: The Essential Reference.

    Science.gov (United States)

    Devine, Carol; Hansen, Carol Rae; Wilde, Ralph; Bronkhorst, Daan; Moritz, Frederic A.; Rolle, Baptiste; Sherman, Rebecca; Southard, Jo Lynn; Wilkinson, Robert; Poole, Hilary, Ed.

    This reference work documents the history of human rights theory, explains each article of the Universal Declaration of Human Rights, explores the contemporary human rights movement, and examines the major human rights issues facing the world today. This book is the first to combine historical and contemporary perspectives on these critical…

  19. The stormy waters of the International Criminal Court: universal fight against impunity or liberal universalization?

    Directory of Open Access Journals (Sweden)

    Mateus Kowalski

    2014-05-01

    Full Text Available The universalistic dimension of the International Criminal Court's (ICC nature and function is clear. Yet, this dimension must be thoroughly defined. We must ask ‘what universalism’? A rational approach to international social relations is different from an ethical one. While the rational approach may lead to universalization of localized specific moral models (e.g. the liberal Western model promoting its hegemony, the ethical approach promotes diversity through considering non-reducible differences and common human phenomena in which only a minimal common ethics is universal. This paper argues that the answer to this structural question is crucial to understand if the ICC is essentially a hegemonic tool to expand the predominant Western liberal model or rather a mechanism to fight impunity acknowledging diversity and rooted on an ethical concern. We contend that the ICC is immersed in troubled waters where it is not always possible to separate a universalizing Western liberal approach from an ethical universal approach. Nevertheless, we conclude that the Court, even if partially and at times serves as tool for hegemony, is essentially defined by the universalization of the fight against impunity through reference to a minimal common ethics.

  20. CURRENT SITUATION OF HUMAN RESOURCES IN ROMANIAN PRE-UNIVERSITY EUCATION CONTEXT OF E.U. INTEGRATION

    Directory of Open Access Journals (Sweden)

    Luminita Claudia CORBU

    2016-02-01

    Full Text Available The paper aims to present development of human resource in the process of accession to the European Union took into account the standards proposed by the European Union, as formulated at the level of principles and objectives, the Single European Act and the Treaty on European Union, including the Treaty Amsterdam, then the sequence of documents developed by the European Commission. It is expected that documents the evolution of education and training in the European Union around concepts such as: further education, knowledge society, knowledge - skills - competitiveness, globalization, discrimination and inequality etc. Around this concept formulated a strategy for workforce training to meet European standards and to escape from captivity regional. But this process of convergent evolution of the labor force for the European market has gone from multiple realities. One of these areas, with its own legacy in terms of human resources and how to perceive its specific educational objectives proposed by Europe was Romania. Knowing one of the toughest centralized systems, the labor market was absorbing all graduates of vocational education, high school and university, after 1989, Romania was confronted with a massive disturbance of the labor market. This dimension has been linked to a certain inadequacies supply training system Romanian, which itself on the one hand, a transformation natural caused by seclusion has been maintained for several years, on the other hand, in a process of adaptation to European standards.