WorldWideScience

Sample records for human gestalt mechanism

  1. [Gestalt therapy.].

    Science.gov (United States)

    Corbeil, J; Poupard, D

    1978-01-01

    The authors describe Gestalt Therapy. They retrace its fundamental theoretical axes. These are psychoanalysis, character analysis, the german Gestalt theory of perception, existentialism, and the Orient. Some principal concepts are then elaborated more fully such as the cycle of awareness, desensitization, excitation anxiety and the five defense mechanisms: retroflection, introjection, projection, deflection, and confluence. The nature and goals of the therapeutic process are also described before the presentation of some techniques specific to this approach such as enactment and role playing. Finally, certain basic Gestalt rules, which aim at facilitating and intensifying the communication process among group members, are enunciated.

  2. Gestalt Processing in Human-Robot Interaction: A Novel Account for Autism Research

    Directory of Open Access Journals (Sweden)

    Maya Dimitrova

    2015-12-01

    Full Text Available The paper presents a novel analysis focused on showing that education is possible through robotic enhancement of the Gestalt processing in children with autism, which is not comparable to alternative educational methods such as demonstration and instruction provided solely by human tutors. The paper underlines the conceptualization of cognitive processing of holistic representations traditionally named in psychology as Gestalt structures, emerging in the process of human-robot interaction in educational settings. Two cognitive processes are proposed in the present study - bounding and unfolding - and their role in Gestalt emergence is outlined. The proposed theoretical approach explains novel findings of autistic perception and gives guidelines for design of robot-assistants to the rehabilitation process.

  3. Gestalt Processing in Human-Robot Interaction: A Novel Account for Autism Research

    Directory of Open Access Journals (Sweden)

    Maya Dimitrova

    2015-12-01

    Full Text Available The paper presents a novel analysis focused on showing that education is possible through robotic enhancement of the Gestalt processing in children with autism, which is not comparable to alternative educational methods such as demonstration and instruction provided solely by human tutors. The paper underlines the conceptualization of cognitive processing of holistic representations traditionally named in psychology as Gestalt structures, emerging in the process of human-robot interaction in educational settings. Two cognitive processes are proposed in the present study - bounding and unfolding - and their role in Gestalt emergence is outlined. The proposed theoretical approach explains novel findings of autistic perception and gives guidelines for design of robot-assistants to the rehabilitation process.

  4. Coding of melodic gestalt in human auditory cortex.

    Science.gov (United States)

    Schindler, Andreas; Herdener, Marcus; Bartels, Andreas

    2013-12-01

    The perception of a melody is invariant to the absolute properties of its constituting notes, but depends on the relation between them-the melody's relative pitch profile. In fact, a melody's "Gestalt" is recognized regardless of the instrument or key used to play it. Pitch processing in general is assumed to occur at the level of the auditory cortex. However, it is unknown whether early auditory regions are able to encode pitch sequences integrated over time (i.e., melodies) and whether the resulting representations are invariant to specific keys. Here, we presented participants different melodies composed of the same 4 harmonic pitches during functional magnetic resonance imaging recordings. Additionally, we played the same melodies transposed in different keys and on different instruments. We found that melodies were invariantly represented by their blood oxygen level-dependent activation patterns in primary and secondary auditory cortices across instruments, and also across keys. Our findings extend common hierarchical models of auditory processing by showing that melodies are encoded independent of absolute pitch and based on their relative pitch profile as early as the primary auditory cortex.

  5. Relationship of Bender Gestalt Developmental Scores and Human Drawing Developmental Scores in a Sample of Turkish Preschool Children

    Science.gov (United States)

    Ozer, Serap

    2009-01-01

    The Bender Gestalt test and Human Drawings are frequently utilized tests in assessing school readiness in children. This study was a pilot attempt to evaluate these two tests in a Turkish sample as they relate to first grade behaviour as measured by teacher ratings. One hundred and five children were evaluated at the end of kindergarten using the…

  6. Relationship of Bender Gestalt Developmental Scores and Human Drawing Developmental Scores in a Sample of Turkish Preschool Children

    Science.gov (United States)

    Ozer, Serap

    2009-01-01

    The Bender Gestalt test and Human Drawings are frequently utilized tests in assessing school readiness in children. This study was a pilot attempt to evaluate these two tests in a Turkish sample as they relate to first grade behaviour as measured by teacher ratings. One hundred and five children were evaluated at the end of kindergarten using the…

  7. Gestalt Therapy: Its Inheritance from Gestalt Psychology.

    Science.gov (United States)

    Yontef, Gary M.

    When adequately elaborated, the basic method of Gestalt therapy can be traced to the phenomenological field theory of Gestalt psychology. Gestalt therapy differs from Gestalt psychology not because of a difference in philosophy or method, but because of different contexts; the clinical context has different demands than those of basic research.…

  8. Gestalt factors modulate basic spatial vision.

    Science.gov (United States)

    Sayim, B; Westheimer, G; Herzog, M H

    2010-05-01

    Human perception of a stimulus varies depending on the context in which the stimulus is presented. Such contextual modulation has often been explained by two basic neural mechanisms: lateral inhibition and spatial pooling. In the present study, we presented observers with a vernier stimulus flanked by single lines; observers' ability to discriminate the offset direction of the vernier stimulus deteriorated in accordance with both explanations. However, when the flanking lines were part of a geometric shape (i.e., a good Gestalt), this deterioration strongly diminished. These findings cannot be explained by lateral inhibition or spatial pooling. It seems that Gestalt factors play an important role in contextual modulation. We propose that contextual modulation can be used as a quantitative measure to investigate the rules governing the grouping of elements into meaningful wholes.

  9. Using Gestalt Psychodrama Experiments in Rehabilitation Counseling

    Science.gov (United States)

    Coven, A. B.

    1977-01-01

    Gestalt therapy is an existential helping approach that assumes human beings have the potential to choose their behavior and thus define their own meaning in life. Applying Gestalt theory, disabled persons can define the meaning of the disability to their total person. (Author)

  10. The Bender Gestalt Test with the Human Figure Drawing Test for Young School Children. A Manual for Use with the Koppitz Scoring System.

    Science.gov (United States)

    Koppitz, Elizabeth Munsterberg

    Presented is a manual for scoring the Bender Gestalt Test and the Human Figure Drawing Test for screening and diagnostic uses with emotionally disturbed, brain damaged, or perceptually handicapped 5- to 11-year-old children. Given are suggestions for administering and scoring the Bender test which examines distortion of shape, rotation,…

  11. Gestalt Interactional Groups

    Science.gov (United States)

    Harman, Robert L.; Franklin, Richard W.

    1975-01-01

    Gestalt therapy in groups is not limited to individual work in the presence of an audience. Describes several ways to involve gestalt groups interactionally. Interactions described focus on learning by doing and discovering, and are noninterpretive. (Author/EJT)

  12. Awareness in Gestalt sex therapy.

    Science.gov (United States)

    Mosher, D L

    1979-01-01

    Awareness is conceived to be selective, curative, a method, a prescription for ideal living, and a ground for human existence. In this paper the following gestalt awareness methods are described: continuum of awareness, awareness questions, biobehavioral feedback, directed awareness, concentration, present-centering, taking responsibilty, and shuttles in awareness. The use of these methods is illustrated in a gestalt therapy dialogue. The application of awareness as concept and method to sensate focus and to the treatment of the prematurely ejaculating male is discussed. Shuttles in awareness and the shared continua of awareness are introduced as promising new methods in the treatment of sexual dysfunction and as enhancing sexual pleasure and communion.

  13. First, you need a Gestalt: An interaction of bottom-up and top-down streams during the perception of the ambiguously rotating human walker.

    Science.gov (United States)

    Pastukhov, Alexander

    2017-04-25

    Our visual system combines sensory evidence with prior knowledge to produce a representation of an outside world. Here, we explored the limits of the feedforward computation using an ambiguously rotating human biological motion. Specifically, we investigated whether an overall rotation, which was added to all the displays used in the study, would be perceived when the point-light walker was presented upside-down, a condition that typically obliterates perception of a human Gestalt. We report that inversion of the point-light walker or the absence of an identifiable Gestalt abolished the perception of an overall rotation. Perception of rotation was restored if the human walker Gestalt could be identified (an upright walker), if observers were informed about the nature of the motion display, or if observers expected to see the rotation of an unknown dynamic object. This implies that a mathematically more complex human motion was accounted for before the remaining motion components could be used to infer an overall rotation. Our results indicate that the perceptual inference does not proceed in a hierarchical manner with the simpler components being identified first. Instead, prior knowledge acts as a starting point for the decomposition of an even relatively simple combination of two motions.

  14. Simultanagnosia does not affect processes of auditory Gestalt perception.

    Science.gov (United States)

    Rennig, Johannes; Bleyer, Anna Lena; Karnath, Hans-Otto

    2017-05-01

    Simultanagnosia is a neuropsychological deficit of higher visual processes caused by temporo-parietal brain damage. It is characterized by a specific failure of recognition of a global visual Gestalt, like a visual scene or complex objects, consisting of local elements. In this study we investigated to what extend this deficit should be understood as a deficit related to specifically the visual domain or whether it should be seen as defective Gestalt processing per se. To examine if simultanagnosia occurs across sensory domains, we designed several auditory experiments sharing typical characteristics of visual tasks that are known to be particularly demanding for patients suffering from simultanagnosia. We also included control tasks for auditory working memory deficits and for auditory extinction. We tested four simultanagnosia patients who suffered from severe symptoms in the visual domain. Two of them indeed showed significant impairments in recognition of simultaneously presented sounds. However, the same two patients also suffered from severe auditory working memory deficits and from symptoms comparable to auditory extinction, both sufficiently explaining the impairments in simultaneous auditory perception. We thus conclude that deficits in auditory Gestalt perception do not appear to be characteristic for simultanagnosia and that the human brain obviously uses independent mechanisms for visual and for auditory Gestalt perception. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. 论认知视域下格式塔意象的细节构建机制--以《浮生六记》英译本为例%On the Constructive Mechanism of the Details of Image-Gestalt in the Cognitive Perspective---A Case Study of English Translation of Six Chapters of a Floating Life

    Institute of Scientific and Technical Information of China (English)

    李文琼

    2014-01-01

    Gestalt psychology is widely used in numerous fields of humanities and social sciences due to its universal effect. In the study of literary translation , Nida, Holmes and Bell successively raise disparate transformation patterns between two languages , directing the research orientation of translation to the operating mechanism of the translator’s psychological cognition. Based on previous studies, Jiang Qiuxia puts forward the transformation schema of image -gestalt dominated by aesthetic connotation. Though the transformation schema of image-gestalt realizes the perfect combination between gestalt psychology and translation aesthetics for the very first time , the relevant details of implementation fails to be specified. This paper dissects Six Chapters of a Floating Life translated by Lin Yutang with multiple perspectives and finds out that the reconstruction of image-gestalt involves aesthetic mentality of the audiences and the cognitive structure of the translator. Moreover, the restoration degree of gestalt quality in the source text closely relates to the language rhythm, the dynamic balance of cultural distance as well as the equivalent transformation of the integral image. This paper finally concludes that the cognitive description towards image-gestalt is feasible and effective.%姜秋霞提出的“格式塔意象”语言转换模式虽然实现了格式塔心理学与翻译美学的完美结合,却没有规定格式塔意象图式的具体构建细节。通过对林语堂《浮生六记》的英译本进行多角度的细致剖析,笔者发现格式塔意象的再造过程涉及受众主体的审美心理和译者自身的认知结构,源文本格式塔质的还原程度与语言节奏的审美功能、文化距离的动态平衡及整体意象的对等转换密切相关,从认知层面对格式塔意象进行细节描述具有可行性和有效性。

  16. Image processing analysis of traditional Gestalt vision experiments

    Science.gov (United States)

    McCann, John J.

    2002-06-01

    In the late 19th century, the Gestalt Psychology rebelled against the popular new science of Psychophysics. The Gestalt revolution used many fascinating visual examples to illustrate that the whole is greater than the sum of all the parts. Color constancy was an important example. The physical interpretation of sensations and their quantification by JNDs and Weber fractions were met with innumerable examples in which two 'identical' physical stimuli did not look the same. The fact that large changes in the color of the illumination failed to change color appearance in real scenes demanded something more than quantifying the psychophysical response of a single pixel. The debates continues today with proponents of both physical, pixel-based colorimetry and perceptual, image- based cognitive interpretations. Modern instrumentation has made colorimetric pixel measurement universal. As well, new examples of unconscious inference continue to be reported in the literature. Image processing provides a new way of analyzing familiar Gestalt displays. Since the pioneering experiments by Fergus Campbell and Land, we know that human vision has independent spatial channels and independent color channels. Color matching data from color constancy experiments agrees with spatial comparison analysis. In this analysis, simple spatial processes can explain the different appearances of 'identical' stimuli by analyzing the multiresolution spatial properties of their surrounds. Benary's Cross, White's Effect, the Checkerboard Illusion and the Dungeon Illusion can all be understood by the analysis of their low-spatial-frequency components. Just as with color constancy, these Gestalt images are most simply described by the analysis of spatial components. Simple spatial mechanisms account for the appearance of 'identical' stimuli in complex scenes. It does not require complex, cognitive processes to calculate appearances in familiar Gestalt experiments.

  17. Perceiving conspecifics as integrated body-gestalts is an embodied process.

    Science.gov (United States)

    Kessler, Klaus; Miellet, Sebastien

    2013-08-01

    We investigated the effect of posture congruence on social perception. Specifically, we tested the hypothesis that completing "body gestalts," rather than being a purely visual process, is mediated by congruence in the postures of observer and stimulus. We developed novel stimuli showing a face and 2 hands that could be combined in various ways to form "body gestalts" implying different postures. In 3 experiments we found that imitative finger movements were consistently faster when the observer's posture matched the posture implied by the configuration of face and hands shown onscreen, suggesting that participants intuitively used their own body schema to "fill in the gaps" in the stimuli. Besides shaping how humans perceive others' bodies, embodied body-gestalt (eBG) completion may be an essential social and survival mechanism, for example, allowing for quick recovery from deceptive actions. It may also partly explain why humans subconsciously align themselves in everyday interactions: This might facilitate optimal corepresentation at higher, conscious levels.

  18. Gestalt theory: implications for radiology education.

    Science.gov (United States)

    Koontz, Nicholas A; Gunderman, Richard B

    2008-05-01

    The Gestalt theory of modern psychology is grounded in the ideas that holistic rather than atomistic approaches are necessary to understand the mind, and that the mental whole is greater than the sum of its component parts. Although the Gestalt school fell out of favor due to its descriptive rather than explanatory nature, it permanently changed our understanding of perception. For the radiologist, such fundamental Gestalt concepts as figure-ground relationships and a variety of "grouping principles" (the laws of closure, proximity, similarity, common region, continuity, and symmetry) are ubiquitous in daily work, not to mention in art and personal life. By considering the applications of these principles and the stereotypical ways in which humans perceive visual stimuli, a radiology learner may incur fewer errors of diagnosis. This article serves to introduce several important principles of Gestalt theory, identify examples of these principles in widely recognizable fine art, and highlight their implications for radiology education.

  19. On the gestalt concept.

    Science.gov (United States)

    Breidbach, Olaf; Jost, Jürgen

    2006-08-01

    We define a gestalt as the invariants of a collection of patterns that can mutually be transformed into each other through a class of transformations encoded by, or conversely, determining that gestalt. The class of these transformations needs to satisfy structural regularities like the ones of the mathematical structure of a group. This makes an analysis of a gestalt possible in terms of relations between its representing patterns. While the gestalt concept has its origins in cognitive psychology, it has also important implications for morphology.

  20. Intermediate grouping on remotely sensed data using Gestalt algebra

    Science.gov (United States)

    Michaelsen, Eckart

    2014-10-01

    Human observers often achieve striking recognition performance on remotely sensed data unmatched by machine vision algorithms. This holds even for thermal images (IR) or synthetic aperture radar (SAR). Psychologists refer to these capabilities as Gestalt perceptive skills. Gestalt Algebra is a mathematical structure recently proposed for such laws of perceptual grouping. It gives operations for mirror symmetry, continuation in rows and rotational symmetric patterns. Each of these operations forms an aggregate-Gestalt of a tuple of part-Gestalten. Each Gestalt is attributed with a position, an orientation, a rotational frequency, a scale, and an assessment respectively. Any Gestalt can be combined with any other Gestalt using any of the three operations. Most often the assessment of the new aggregate-Gestalt will be close to zero. Only if the part-Gestalten perfectly fit into the desired pattern the new aggregate-Gestalt will be assessed with value one. The algebra is suitable in both directions: It may render an organized symmetric mandala using random numbers. Or it may recognize deep hidden visual relationships between meaningful parts of a picture. For the latter primitives must be obtained from the image by some key-point detector and a threshold. Intelligent search strategies are required for this search in the combinatorial space of possible Gestalt Algebra terms. Exemplarily, maximal assessed Gestalten found in selected aerial images as well as in IR and SAR images are presented.

  1. Gestalt y aprendizaje / Gestalt and learning

    Directory of Open Access Journals (Sweden)

    Fallas Vargas, Fabrizio

    2008-04-01

    Full Text Available Resumen: El presente trabajo explora las principales implicaciones de la teoría Gestalt en tanto que modelo de aprendizaje. Para ello desarrolla las categorías de análisis fundamental producidas por sus exponentes fundadores, Wertheimer, Koffka, y Köhler, el concepto de pensamiento productivo, así como las reglas perceptuales derivadas de sus investigaciones empíricas. Asimismo se exploran aplicaciones pedagógicas y psicopedagógicas de la teoría, en articulación con el concepto axial de la Gestalt en términos de aprendizaje: die Einsicht, el cual es elaborado en forma crítica.Abstract: This paper explores the main implications of Gestalt theory as a model of learning. To achieve that purpose, it develops the categories of fundamental analysis conceived by it´s founders: Wertheimer, Koffka, and Köhler. It also develops the concept of productive thinking, as well as the rules of perception derived from their empirical investigations. Likewise, it explores pedagogical and psychopedagogical applications of the theory, articulated with the axial concept of Gestalt theory, in terms of learning: die Einsicht, which is elaborated in a critical approach.

  2. Interactional Gestalt Therapy.

    Science.gov (United States)

    Warehime, Robert G.

    1981-01-01

    Group gestalt therapy in which the leader facilitates the development of helping capacity in group members is described. The general characteristics of this approach are discussed and ground rules concerning leader and member behaviors are suggested. (RC)

  3. Learning theory and gestalt therapy.

    Science.gov (United States)

    Harper, R; Bauer, R; Kannarkat, J

    1976-01-01

    This article discusses the theory and operations of Gestalt Therapy from the viewpoint of learning theory. General comparative issues are elaborated as well as the concepts of introjection, retroflextion, confluence, and projection. Principles and techniques of Gestalt Therapy are discussed in terms of learning theory paradigm. Practical implications of the various Gestalt techniques are presented.

  4. Gestalt therapy: theory and practice.

    Science.gov (United States)

    Jones, A

    Gestalt therapy, a particular type of psychotherapy, draws on existential and various Eastern philosophies, and aims to enable the individual to seek his or her own solutions to personal problems. Literally translated as 'whole', Gestalt focuses the individual to appreciate and experience the present. This article examines the Gestalt theory and considers its application to a terminally ill client and his wife.

  5. Multiple Fingers - One Gestalt.

    Science.gov (United States)

    Lezkan, Alexandra; Manuel, Steven G; Colgate, J Edward; Klatzky, Roberta L; Peshkin, Michael A; Drewing, Knut

    2016-01-01

    The Gestalt theory of perception offered principles by which distributed visual sensations are combined into a structured experience ("Gestalt"). We demonstrate conditions whereby haptic sensations at two fingertips are integrated in the perception of a single object. When virtual bumps were presented simultaneously to the right hand's thumb and index finger during lateral arm movements, participants reported perceiving a single bump. A discrimination task measured the bump's perceived location and perceptual reliability (assessed by differential thresholds) for four finger configurations, which varied in their adherence to the Gestalt principles of proximity (small versus large finger separation) and synchrony (virtual spring to link movements of the two fingers versus no spring). According to models of integration, reliability should increase with the degree to which multi-finger cues integrate into a unified percept. Differential thresholds were smaller in the virtual-spring condition (synchrony) than when fingers were unlinked. Additionally, in the condition with reduced synchrony, greater proximity led to lower differential thresholds. Thus, with greater adherence to Gestalt principles, thresholds approached values predicted for optimal integration. We conclude that the Gestalt principles of synchrony and proximity apply to haptic perception of surface properties and that these principles can interact to promote multi-finger integration.

  6. Dreams and gestalt therapy

    OpenAIRE

    Vásquez, Francisco; Departamento Académico de Psiquiatría, Facultad de Medicina, UNMSM

    2013-01-01

    The dream is described here by in the course of the time and the meaning it has and had according to time and culture. The general theory of dreams is focused from Hippocrates until our days, as well as its psychological, religious and cultural interpretation. Emphasis is made on the therapeutic function of dreams, in the Freudian, Jungian and gestalt therapy. It meditates on Freud’s, Jung’s and Perls’ contributions, enlarging the concepts of dream in the gestalt therapy that considers the dr...

  7. Gestalt y aprendizaje / Gestalt and learning

    OpenAIRE

    Fallas Vargas, Fabrizio

    2008-01-01

    Resumen: El presente trabajo explora las principales implicaciones de la teoría Gestalt en tanto que modelo de aprendizaje. Para ello desarrolla las categorías de análisis fundamental producidas por sus exponentes fundadores, Wertheimer, Koffka, y Köhler, el concepto de pensamiento productivo, así como las reglas perceptuales derivadas de sus investigaciones empíricas. Asimismo se exploran aplicaciones pedagógicas y psicopedagógicas de la teoría, en articulación con el concepto axial de la Ge...

  8. Playing Games with Games People Play. Contributions of Gestalt Theory to Individual Counseling. Self-Discovery through Art: A Group Experience. A Review of Personal Research on Experimental-Gestalt Growth Groups. Gestalt Dreamwork as a Method for Self Discovery.

    Science.gov (United States)

    Guinan, James F.; And Others

    The existential Gestalt approach to facilitating the human growth process is discussed, from somewhat different vantage points, in these papers. Two seek to elaborate the basic principles and facilitating "techniques" of Gestalt therapy, while maintaining that one can truly understand only by experiencing. The use of Focus Groups, in which a focal…

  9. Gestalt psychology in Italy.

    Science.gov (United States)

    Verstegen, I

    2000-01-01

    Graz gestalt psychology was introduced into Italy after World War I with Vittorio Benussi's emigration to Padua. His earliest adherent, Cesare Musatti, defended Graz theory, but after Benussi's premature death became an adherent of the Berlin gestalt psychology of Wertheimer-Köhler-Koffka. He trained his two most important students, Fabio Metelli and Gaetano Kanizsa, in orthodox Berlin theory. They established rigid "schools" in Padua and Trieste. The structure of Italian academics allowed for such strict orthodoxy, quite unlike the situation in America, where scientific objectivity mitigated against schools. In the 1960s, some of the students of Metelli and Kanizsa (above all Bozzi) initiated a realist movement-felt in Kanizsa's late work-that was quite independent of that of J. J. Gibson. Finally, more recently, Benussi and Graz theorizing have been embraced again, sentimentally, as a predecedent to Kanizsa-Bozzi.

  10. Gestalt y Aprendizaje

    Directory of Open Access Journals (Sweden)

    Fabrizio Fallas Vargas

    2008-01-01

    Full Text Available El presente trabajo explora las principales implicaciones de la teoría Gestalt en tanto que modelo de aprendizaje. Para ello desarrolla las categorías de análisis fundamental producidas por sus exponentes fundadores, Wertheimer, Koffka, y Köhler, el concepto de pensamiento productivo, así como las reglas perceptuales derivadas de sus investigaciones empíricas. Asimismo se exploran aplicaciones pedagógicas y psicopedagógicas de la teoría, en articulación con el concepto axial de la Gestalt en términos de aprendizaje: die Einsicht, el cual es elaborado en forma crítica.

  11. Gestalt Therapy and the Cousellor

    Science.gov (United States)

    Peavy, R. Vance

    1973-01-01

    The article briefly describes the principal values in Gestalt Therapy and outlines some of the practices commonly employed in Gestalt work. Implications for counsellors are suggested--both as a mode of counsellor training and as an approach to be used by counsellors. (Author)

  12. Gestalt Approach to Family Therapy.

    Science.gov (United States)

    Bauer, Rudolph

    1979-01-01

    Gestalt psychotherapy is presented as a synthesis of a number of psychological traditions. Two particular techniques are described in detail: the empty chair technique which is a strategy that focuses on the parents' internalized object relations which are played out between themselves and with their children and the Gestalt experiment. (Author)

  13. The Legacy of Gestalt Psychology.

    Science.gov (United States)

    Rock, Irvin; Palmer, Stephen

    1990-01-01

    Discussed are the principles of Gestalt psychology and the history and future of the movement. A comparison of Gestalt, Behaviorist, and Structuralist ideas is included. The study of perception, learning, memory, and thinking from the Gestaltist point of view is described. (KR)

  14. Gestalt Psychology and Bilingual Education.

    Science.gov (United States)

    Blomstedt, Bob; And Others

    Several concepts detailed in Gestalt psychology/therapy appear to have a close relationship with many concepts being applied in bilingual education. The primary contribution of Gestalt psychology to learning theory in the U.S. is an emphasis on perception and reintegration of relationships within an organized whole. To the teacher this means that…

  15. Gestalt Theory and Instructional Design.

    Science.gov (United States)

    Moore, Patrick; Fitz, Chad

    1993-01-01

    Offers a brief overview of Gestalt theory. Shows how six Gestalt principles (proximity, closure, symmetry, figure-ground segregation, good continuation, and similarity) can be applied to improve a reader's comprehension of a badly designed instruction module that uses several graphics. (SR)

  16. Gestalt Therapy and the Specious Present.

    Science.gov (United States)

    Nordberg, Robert

    Whereas Gestalt Therapy purports to apply the principles of Gestalt psychology to psychotherapeutic situations, its emphasis upon the here-and-now and upon sensations as distinct from meanings is directly contrary to the spirit and assumptions of Gestalt theory as developed by Max Wertheimer and others. When Gestalt therapy does succeed, it is by…

  17. Gestalt Therapy and the Specious Present.

    Science.gov (United States)

    Nordberg, Robert

    Whereas Gestalt Therapy purports to apply the principles of Gestalt psychology to psychotherapeutic situations, its emphasis upon the here-and-now and upon sensations as distinct from meanings is directly contrary to the spirit and assumptions of Gestalt theory as developed by Max Wertheimer and others. When Gestalt therapy does succeed, it is by…

  18. Gestalt y Aprendizaje

    OpenAIRE

    Fabrizio Fallas Vargas

    2008-01-01

    El presente trabajo explora las principales implicaciones de la teoría Gestalt en tanto que modelo de aprendizaje. Para ello desarrolla las categorías de análisis fundamental producidas por sus exponentes fundadores, Wertheimer, Koffka, y Köhler, el concepto de pensamiento productivo, así como las reglas perceptuales derivadas de sus investigaciones empíricas. Asimismo se exploran aplicaciones pedagógicas y psicopedagógicas de la teoría, en articulación con el concepto axial de la...

  19. Gestalt and phenomenal transparency.

    Science.gov (United States)

    Koenderink, Jan; van Doorn, Andrea; Pont, Sylvia; Richards, Whitman

    2008-01-01

    Phenomenal transparency is commonly studied by using a stimulus configuration introduced by Metelli: a bipartite patch, divided into equal left and right halves is overlaid with a smaller, concentric bipartite patch, divided along the same line. Observers are instructed to report either a transparent patch over an opaque bipartite field or a mosaic of four opaque patches. We show theoretically and empirically that these are only two of five generic perceptual categories, namely, transparent patch, transparent annulus (hole), mosaic, partial transparency, and multiple transparency (ambiguous) cases. Thus Gestalt factors complicate the interpretation "phenomenal transparency." We propose a framework that avoids this complication. There is excellent agreement between predictions and results.

  20. Some gestalt contributions to psychiatry.

    Science.gov (United States)

    Clegg, Kathleen A

    2010-07-01

    Gestalt theory and methods support significant behavioral change and personal growth, yet they have not been widely incorporated into modern psychiatric practice. Challenges to employing Gestalt principles in psychiatric practice exist, such as focus on diagnosis to guide treatment planning, key elements of psychiatric training, primacy of medication management in psychiatric practice, and financial pressures. However, the concepts of the co-created relational field in the here and now, the paradoxical theory of change, the cycle of experience, and the use of experiment are Gestalt concepts and methods that can be effectively applied in the modern practice of clinical psychiatry and psychiatric education.

  1. On computational Gestalt detection thresholds.

    Science.gov (United States)

    Grompone von Gioi, Rafael; Jakubowicz, Jérémie

    2009-01-01

    The aim of this paper is to show some recent developments of computational Gestalt theory, as pioneered by Desolneux, Moisan and Morel. The new results allow to predict much more accurately the detection thresholds. This step is unavoidable if one wants to analyze visual detection thresholds in the light of computational Gestalt theory. The paper first recalls the main elements of computational Gestalt theory. It points out a precision issue in this theory, essentially due to the use of discrete probability distributions. It then proposes to overcome this issue by using continuous probability distributions and illustrates it on the meaningful alignment detector of Desolneux et al.

  2. Parietal cortex mediates conscious perception of illusory gestalt.

    Science.gov (United States)

    Zaretskaya, Natalia; Anstis, Stuart; Bartels, Andreas

    2013-01-09

    Grouping local elements into a holistic percept, also known as spatial binding, is crucial for meaningful perception. Previous studies have shown that neurons in early visual areas V1 and V2 can signal complex grouping-related information, such as illusory contours or object-border ownerships. However, relatively little is known about higher-level processes contributing to these signals and mediating global Gestalt perception. We used a novel bistable motion illusion that induced alternating and mutually exclusive vivid conscious experiences of either dynamic illusory contours forming a global Gestalt or moving ungrouped local elements while the visual stimulation remained the same. fMRI in healthy human volunteers revealed that activity fluctuations in two sites of the parietal cortex, the superior parietal lobe and the anterior intraparietal sulcus (aIPS), correlated specifically with the perception of the grouped illusory Gestalt as opposed to perception of ungrouped local elements. We then disturbed activity at these two sites in the same participants using transcranial magnetic stimulation (TMS). TMS over aIPS led to a selective shortening of the duration of the global Gestalt percept, with no effect on that of local elements. The results suggest that aIPS activity is directly involved in the process of spatial binding during effortless viewing in the healthy brain. Conscious perception of global Gestalt is therefore associated with aIPS function, similar to attention and perceptual selection.

  3. Cortical Thought Theory: A Working Model of the Human Gestalt Mechanism.

    Science.gov (United States)

    1985-07-01

    SUMFILE(7hSECFIL(7) DIMENSION RINP (4098) DIMENSION A(2,2)oCRAY(64,64) CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC C C...THE DIMENSION OF A(IADEM,IADEM) IADEM=2 C IDEM IS THE DIMENSION RINP AND RIMP AND THE LENGTH OF FFT’S TAKEN IDEM=4096 (. PEALL=L SCALE=40./(ALOGIO...lRINP(J),J=1,L),AMAX,PWR IF(PWR .T. 3.000E7)CO TO 9999 RSUM=O. AMAXUP=+1B. +ALOG1O(PWR)𔃻O. DO 6022 J=1,L RINP (J)=( RINP (J) "AMAXUP+VWIND)*LOCLEN/VWIND

  4. The Gestalt Experiment in Sex Therapy.

    Science.gov (United States)

    Mosher, Donald L.

    1979-01-01

    The Gestalt experiment is applicable to sex therapy. Familiarity with modes and methods of experimenting permits the therapist's creativity to emerge. Applications of sexual metaphors and sex dysfunction as a nightmare are presented, using methods drawn from Gestalt dream work. The use of Gestalt experiments are illustrated in a client-therapist…

  5. Gestalt Therapy: Development, Theory, and Techniques.

    Science.gov (United States)

    Witchel, Robert

    This paper presents a full review of the literature in the area of Gestalt Therapy and could be helpful in familiarizing people with this discipline. The roots contributing to the development of Gestalt therapy as presently practiced are explored briefly. Gestalt theory is presented in a developmental way, initially exploring the relationship…

  6. Perceptual Grouping via Untangling Gestalt Principles

    DEFF Research Database (Denmark)

    Qi, Yonggang; Guo, Jun; Li, Yi

    2013-01-01

    Gestalt principles, a set of conjoining rules derived from hu- man visual studies, have been known to play an important role in computer vision. Many applications such as image segmentation, contour grouping and scene understanding of- ten rely on such rules to work. However, the problem of Gestalt...... the importance of Gestalt rules by solving a learning to rank problem, and formulate a multi-label graph-cuts algo- rithm to group image primitives while taking into account the learned Gestalt confliction. Our experiment results confirm the existence of Gestalt confliction in perceptual grouping and demonstrate...

  7. Perceptual Grouping via Untangling Gestalt Principles

    DEFF Research Database (Denmark)

    Qi, Yonggang; Guo, Jun; Li, Yi

    2013-01-01

    Gestalt principles, a set of conjoining rules derived from hu- man visual studies, have been known to play an important role in computer vision. Many applications such as image segmentation, contour grouping and scene understanding of- ten rely on such rules to work. However, the problem of Gestalt...... the importance of Gestalt rules by solving a learning to rank problem, and formulate a multi-label graph-cuts algo- rithm to group image primitives while taking into account the learned Gestalt confliction. Our experiment results confirm the existence of Gestalt confliction in perceptual grouping and demonstrate...

  8. Bilateral theta-burst TMS to influence global gestalt perception.

    Science.gov (United States)

    Ritzinger, Bernd; Huberle, Elisabeth; Karnath, Hans-Otto

    2012-01-01

    While early and higher visual areas along the ventral visual pathway in the inferotemporal cortex are critical for the recognition of individual objects, the neural representation of human perception of complex global visual scenes remains under debate. Stroke patients with a selective deficit in the perception of a complex global Gestalt with intact recognition of individual objects - a deficit termed simultanagnosia - greatly helped to study this question. Interestingly, simultanagnosia typically results from bilateral lesions of the temporo-parietal junction (TPJ). The present study aimed to verify the relevance of this area for human global Gestalt perception. We applied continuous theta-burst TMS either unilaterally (left or right) or bilateral simultaneously over TPJ. Healthy subjects were presented with hierarchically organized visual stimuli that allowed parametrical degrading of the object at the global level. Identification of the global Gestalt was significantly modulated only for the bilateral TPJ stimulation condition. Our results strengthen the view that global Gestalt perception in the human brain involves TPJ and is co-dependent on both hemispheres.

  9. Bilateral theta-burst TMS to influence global gestalt perception.

    Directory of Open Access Journals (Sweden)

    Bernd Ritzinger

    Full Text Available While early and higher visual areas along the ventral visual pathway in the inferotemporal cortex are critical for the recognition of individual objects, the neural representation of human perception of complex global visual scenes remains under debate. Stroke patients with a selective deficit in the perception of a complex global Gestalt with intact recognition of individual objects - a deficit termed simultanagnosia - greatly helped to study this question. Interestingly, simultanagnosia typically results from bilateral lesions of the temporo-parietal junction (TPJ. The present study aimed to verify the relevance of this area for human global Gestalt perception. We applied continuous theta-burst TMS either unilaterally (left or right or bilateral simultaneously over TPJ. Healthy subjects were presented with hierarchically organized visual stimuli that allowed parametrical degrading of the object at the global level. Identification of the global Gestalt was significantly modulated only for the bilateral TPJ stimulation condition. Our results strengthen the view that global Gestalt perception in the human brain involves TPJ and is co-dependent on both hemispheres.

  10. The Gestalt approach to stuttering.

    Science.gov (United States)

    Kaplan, N R; Kaplan, M L

    1978-02-01

    This article describes the application of Gestalt therapy concepts to the treatment of stuttering. Within this framework stuttering is seen as an organized self-system rather than a symptom. This self-system is maintained and reinforced by the stutter's experience of this physical self, self-expectancies, self-messages, projections on others, and total viewing of self as a limited and inadequate person. The individual enmeshes himself or herself into this system and restricts himself to familiar behaviors, in this case stuttering, because he has no framework for other ways of functioning. The Gestalt therapeutic framework as a basis of unlocking the individual's limited style of functioning is explored.

  11. Gestalt Approaches to Conjoint Therapy

    Science.gov (United States)

    Kelly, Brian J.; Gill, John D.

    1978-01-01

    An alternative to individual counseling is marriage and family counseling. It is the preferred mode of treatment for all but the social isolate. The specific methods by which persons avoid healthy contacts are discussed, as are counseling methodologies which are based on Gestalt and family systems theory. (Author)

  12. Gestalt Effect of Self Assessment

    Science.gov (United States)

    McDonald, Betty

    2012-01-01

    Defining self assessment as the involvement of students in identifying standards and/or criteria to apply to their work and making judgements about the extent to which they have met these criteria and standards, this paper seeks to highlight the gestalt effect of self assessment. The total effect of self assessment on the learner is greater than…

  13. Gestalt perception is associated with reduced parietal beta oscillations.

    Science.gov (United States)

    Zaretskaya, Natalia; Bartels, Andreas

    2015-05-15

    The ability to perceive composite objects as a whole is fundamental for visual perception in a complex and cluttered natural environment. This ability may be mediated by increased communication between neural representations of distinct object elements, and has been linked to increased synchronization of oscillatory brain activity in the gamma band. Previous studies of perceptual grouping either guided attention between local and global aspects of a given stimulus or manipulated its physical properties to achieve grouped and ungrouped perceptual conditions. In contrast to those studies, we fully matched the physical properties underlying global and local percepts using a bistable stimulus that causes the viewer to perceive either local motion of multiple elements or global motion of two illusory shapes without any external change. To test the synchronization hypothesis we recorded brain activity with EEG, while human participants viewed the stimulus and reported changes in their perception. In contrast to previous findings we show that power of the beta-band was lower during perception of global Gestalt than during that of local elements. Source localization places these differences in the posterior parietal cortex, overlapping with a site previously associated with both attention and Gestalt perception. These findings reveal a role of parietal beta-band activity in internally, rather than externally or attention-driven processes of Gestalt perception. They also add to the growing evidence for shared neural substrates of attention and Gestalt perception, both being linked to parietal cortex. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Use of gestalt in wayfinding design and analysis of wayfinding process

    Institute of Scientific and Technical Information of China (English)

    Li NIU; Leiqing XU; Zhong TANG

    2008-01-01

    The authors brought forward the definition of "Gestalt space" and indicated this kind of space can be easily cognized. Three experiments showed that "clas-sification" and "grouping" are the human strategies to solve wayfinding problems. "Similarity" and "Legibi-lity" of the space are advantageous to help people to com-plete wayfinding tasks. The designer should provide the essential "Legibility" in Gestalt space, by using some tech-niques such as "break" and "accession" to settle the way-finding problem.

  15. Frequency tagging yields an objective neural signature of Gestalt formation.

    Science.gov (United States)

    Alp, Nihan; Kogo, Naoki; Van Belle, Goedele; Wagemans, Johan; Rossion, Bruno

    2016-04-01

    The human visual system integrates separate visual inputs into coherently organized percepts, going beyond the information given. A striking example is the perception of an illusory square when physically separated inducers are positioned and oriented in a square-like configuration (illusory condition). This illusory square disappears when the specific configuration is broken, for instance, by rotating each inducer (non-illusory condition). Here we used frequency tagging and electroencephalography (EEG) to identify an objective neural signature of the global integration required for illusory surface perception. Two diagonal inducers were contrast-modulated at different frequency rates f1 and f2, leading to EEG responses exactly at these frequencies over the occipital cortex. Most importantly, nonlinear intermodulation (IM) components (e.g., f1+f2) appeared in the frequency spectrum, and were much larger in response to the illusory square figure than the non-illusory control condition. Since the IMs reflect long-range interactions between the signals from the inducers, these data provide an objective (i.e., at a precise and predicted EEG frequency) signature of neural processes involved in the emergence of illusory surface perception. More generally, these findings help to establish EEG frequency-tagging as a highly valuable approach to investigate the underlying neural mechanisms of subjective Gestalt phenomena in an objective and quantitative manner, at the system level in humans. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Person-Centered Gestalt Therapy: A Synthesis.

    Science.gov (United States)

    Herlihy, Barbara

    1985-01-01

    Highlights the similarities between the person-centered approach to counseling of Carl Rogers and the Gestalt therapy of Fritz Perls. Discusses implementation of the two approaches and suggests they may be synthesized into a person-centered Gestalt therapy. (MCF)

  17. Gestalt Therapy Interventions for Group Counseling

    Science.gov (United States)

    Passons, William R.

    1972-01-01

    The author offers a brief introduction to some of the basic tenets of Gestalt therapy, noting goals that are similar to those in counseling theories. He also suggests several interventions from Gestalt therapy to be considered for group counseling and discusses their applications. (Author)

  18. Group Counseling Using the Gestalt Approach.

    Science.gov (United States)

    Schneibel, Dan

    The phenomenological-existential therapy known as gestalt therapy sees awareness as its major goal. Clients are helped to become aware of what they are doing, how they are doing it, and how they can change themselves while, at the same time, learning to accept and value themselves. An important topic in the gestalt group process is the key…

  19. Looking at Gestalt Group Impact: An Experiment.

    Science.gov (United States)

    Serok, Shraga; Bar, Ruth

    1984-01-01

    Tested the impact of gestalt group therapy on aspects of self-concept in graduate students (N=33). Results showed a significant rise in decisiveness, general adaptation and self-criticism in the gestalt group as compared to the control groups and showed no significant changes in the self-identification and self-acceptance parameters. (LLL)

  20. Gestalt and Adventure Therapy: Parallels and Perspectives.

    Science.gov (United States)

    Gilsdorf, Rudiger

    This paper calls attention to parallels in the literature of adventure education and that of Gestalt therapy, demonstrating that both are rooted in an experiential tradition. The philosophies of adventure or experiential education and Gestalt therapy have the following areas in common: (1) emphasis on personal growth and the development of present…

  1. Person-Centered Gestalt Therapy: A Synthesis.

    Science.gov (United States)

    Herlihy, Barbara

    1985-01-01

    Highlights the similarities between the person-centered approach to counseling of Carl Rogers and the Gestalt therapy of Fritz Perls. Discusses implementation of the two approaches and suggests they may be synthesized into a person-centered Gestalt therapy. (MCF)

  2. Gestalt and psychoanalytic therapies: structural analysis and rapprochement.

    Science.gov (United States)

    Nielsen, A C

    1980-10-01

    This paper examines the psychoanalytic concepts of interpretation, resistance, and transference as manifest in gestalt therapy. Although these concepts are de-emphasized, criticized, and disavowed in gestalt theoretical writings, they are actually fundamental to the underlying or "deep" structure of gestalt therapy. Examples of gestalt interventions are described and indications for their use suggested.

  3. Mediocrity or Excellence: An Identity Crisis in Gestalt Therapy Training.

    Science.gov (United States)

    Yontef, Gary M.

    Gestalt Therapy is in a growth crisis. In practice, there is an abundance of inadequate practitioners and trainers of Gestalt Therapy. In the literature, there is an abundance of introductory works, a paucity of advanced texts, and a misunderstanding and inadequate representation of Gestalt Therapy. Gestalt Therapy training is confused by unclear…

  4. Gestalt Algebra—A Proposal for the Formalization of Gestalt Perception and Rendering

    OpenAIRE

    Eckart Michaelsen

    2014-01-01

    Gestalt Algebra gives a formal structure suitable for describing complex patterns in the image plain. This can be useful for recognizing hidden structure in images. The work at hand refers to the laws of perceptual psychology. A manifold called the Gestalt Domain is defined. Next to the position in 2D it also contains an orientation and a scale component. Algebraic operations on it are given for mirror symmetry as well as organization into rows. Additionally the Gestalt Domain contains an ass...

  5. The Application of Gestalt Theory in Translation

    Institute of Scientific and Technical Information of China (English)

    于海

    2014-01-01

    The Gestalt theory is an important integral of integrated approach to translation, which tries to bridge the gap between linguistic oriented translation and literary oriented translation. The gestalt principle is a vertical stratificational model, which is proceeds from level A at the top to level F at the bottom. In other words, from the macro- level to the micro- level. Thus, from the perspective of gestalt theory, we can have a holistic understanding of the source text, and at the same time the translated texts would be more precise.

  6. Parietal cortex mediates perceptual Gestalt grouping independent of stimulus size.

    Science.gov (United States)

    Grassi, Pablo R; Zaretskaya, Natalia; Bartels, Andreas

    2016-06-01

    The integration of local moving elements into a unified gestalt percept has previously been linked to the posterior parietal cortex. There are two possible interpretations for the lack of involvement of other occipital regions. The first is that parietal cortex is indeed uniquely functionally specialized to perform grouping. Another possibility is that other visual regions can perform grouping as well, but that the large spatial separation of the local elements used previously exceeded their neurons' receptive field (RF) sizes, preventing their involvement. In this study we distinguished between these two alternatives. We measured whole-brain activity using fMRI in response to a bistable motion illusion that induced mutually exclusive percepts of either an illusory global Gestalt or of local elements. The stimulus was presented in two sizes, a large version known to activate IPS only, and a version sufficiently small to fit into the RFs of mid-level dorsal regions such as V5/MT. We found that none of the separately localized motion regions apart from parietal cortex showed a preference for global Gestalt perception, even for the smaller version of the stimulus. This outcome suggests that grouping-by-motion is mediated by a specialized size-invariant mechanism with parietal cortex as its anatomical substrate. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Analysis of transference in Gestalt group psychotherapy.

    Science.gov (United States)

    Frew, J E

    1990-04-01

    In Gestalt therapy, transference is viewed as a contact boundary disturbance which impairs the patient's ability to accurately perceive the present therapy situation. The boundary disturbances in Gestalt therapy most closely related to the analytic notion of transference are projection, introjection, and confluence. In Gestalt group psychotherapy, group members interfere with the process of need identification and satisfaction by distorting their contact with each other through projecting, introjecting, and being confluent. The Gestalt group therapist uses interventions directed to individuals and to the group to increase participants' awareness of these boundary disturbances and of the present contact opportunities available to them when these disturbances are resolved. In formulating interventions, the leader is mindful of the function of boundary disturbances to the group-as-a-whole as well as to individuals.

  8. [Gestalt therapy of complaints].

    Science.gov (United States)

    De Baranchuk, J Z; Dayan, A; Gomez, A; Grimaldi, S; Morra, A

    1980-03-01

    People can express their suffering voicing it, complaining with their body, with gestures, movements; for alerts eyes it is even more comprehensive and true than words. Complaints that human beings are capable of expressing are not so many, there are only a handful, and this work intends to be exhaustive in its exposition. It is possible to complain against third persons. It is also possible to do so against oneself assuming either the intransigent attitude of a father who judges a son who does not fulfill his expectancies, or as a son who resents the paternal demands which he feels he cannot comply. Other kind of complaints include physical symptoms, either isolated (cephalea, dysnea, urticaria) or constituting syndromes or illnesses. Losses suffered are also a source of complaints, whatever the lost object might be (person, situation, material things or a part of oneself). It can be mourned because of its absence, or else by feeling guilty of the real or imaginary damage inflicted or else by feeling indisolubly linked to it with a phantom tie. Other types of complaints are the feeling of dependancy towards something oppressive, be it a substance, such as alcohol, smoking, drugs or overeating, or it may be a person or a situation. In view of the compulsive addiction characteristics with which the subject lives, it is possible to assimilate this dependancy and the feeling of oppression and damage to the link with a toxic.

  9. Gestalt Workshops: Suggested In-Service Training for Teachers.

    Science.gov (United States)

    Fiordo, Richard

    1981-01-01

    Fritz Perls' Gestalt Workshops are explained and recommended for inservice training for teachers. Since Gestalt Workshops increase their participants' growth, awareness, and integration personally and environmentally, their benefit to classroom teachers would be direct and dramatic. (Author)

  10. Gestalt Principles in the Control of Motor Action

    Science.gov (United States)

    Klapp, Stuart T.; Jagacinski, Richard J.

    2011-01-01

    We argue that 4 fundamental gestalt phenomena in perception apply to the control of motor action. First, a motor gestalt, like a perceptual gestalt, is holistic in the sense that it is processed as a single unit. This notion is consistent with reaction time results indicating that all gestures for a brief unit of action must be programmed prior to…

  11. Gestalt Principles in the Control of Motor Action

    Science.gov (United States)

    Klapp, Stuart T.; Jagacinski, Richard J.

    2011-01-01

    We argue that 4 fundamental gestalt phenomena in perception apply to the control of motor action. First, a motor gestalt, like a perceptual gestalt, is holistic in the sense that it is processed as a single unit. This notion is consistent with reaction time results indicating that all gestures for a brief unit of action must be programmed prior to…

  12. Using Gestalt Theory to Teach Document Design and Graphics.

    Science.gov (United States)

    Moore, Patrick; Fitz, Chad

    1993-01-01

    Presents a brief overview of Gestalt theory. Discusses and illustrates six key principles of Gestalt psychology as they apply to document design and graphics. Presents exercise that students may use to improve their understanding of the principles and develop their document design skills. Distinguishes between Gestalt theory and rhetoric. (RS)

  13. Práce se sny v Gestalt terapii

    OpenAIRE

    Tláskalová, Pavlína

    2009-01-01

    There are presented Gestalt dreamwork methods in this thesis. It describes Gestalt theoretical concepts relevant in work with dreams. Possible therapist's attitudes related to dreamwork are introduced. Qualitative research which maps practical application of dreamwork in Gestalt therapy practice has been carried out.

  14. Using Gestalt Theory to Teach Document Design and Graphics.

    Science.gov (United States)

    Moore, Patrick; Fitz, Chad

    1993-01-01

    Presents a brief overview of Gestalt theory. Discusses and illustrates six key principles of Gestalt psychology as they apply to document design and graphics. Presents exercise that students may use to improve their understanding of the principles and develop their document design skills. Distinguishes between Gestalt theory and rhetoric. (RS)

  15. Gênese e construção de uma filosofia da gestalt na gestalt-terapia

    OpenAIRE

    Granzotto, Rosane Lorena

    2005-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia A Gestalt-terapia é uma proposta de intervenção psicoterapêutica que se entende fundamentada numa leitura gestáltica da metapsicologia freudiana, por um lado, e numa interpretação fenomenológica da Psicologia da Gestalt, por outro. Seu principal mentor, Perls, referiu-se a esses fundamentos como uma sorte de "filosofia da gestalt", parcialmente des...

  16. A Century of Gestalt Psychology in Visual Perception I. Perceptual Grouping and Figure-Ground Organization

    Science.gov (United States)

    Wagemans, Johan; Elder, James H.; Kubovy, Michael; Palmer, Stephen E.; Peterson, Mary A.; Singh, Manish; von der Heydt, Rüdiger

    2012-01-01

    In 1912, Max Wertheimer published his paper on phi motion, widely recognized as the start of Gestalt psychology. Because of its continued relevance in modern psychology, this centennial anniversary is an excellent opportunity to take stock of what Gestalt psychology has offered and how it has changed since its inception. We first introduce the key findings and ideas in the Berlin school of Gestalt psychology, and then briefly sketch its development, rise, and fall. Next, we discuss its empirical and conceptual problems, and indicate how they are addressed in contemporary research on perceptual grouping and figure-ground organization. In particular, we review the principles of grouping, both classical (e.g., proximity, similarity, common fate, good continuation, closure, symmetry, parallelism) and new (e.g., synchrony, common region, element and uniform connectedness), and their role in contour integration and completion. We then review classic and new image-based principles of figure-ground organization, how it is influenced by past experience and attention, and how it relates to shape and depth perception. After an integrated review of the neural mechanisms involved in contour grouping, border-ownership, and figure-ground perception, we conclude by evaluating what modern vision science has offered compared to traditional Gestalt psychology, whether we can speak of a Gestalt revival, and where the remaining limitations and challenges lie. A better integration of this research tradition with the rest of vision science requires further progress regarding the conceptual and theoretical foundations of the Gestalt approach, which will be the focus of a second review paper. PMID:22845751

  17. Preferences for behavioural, analytic and gestalt psychotherapy.

    Science.gov (United States)

    Sobel, H J

    1979-09-01

    This study investigated preferences for behavioural, analytic and gestalt psychotherapy among a sample of 40 SES class III and IV adult females and 67 college freshmen who had never been actual therapy patients. A scaled survey assessed general preference, preference given an imagined long-standing depressive disorder, preference given an imagined specific phobia, and preference for the therapist-patient relationship. Three audio tapes were designed, each describing one of the modalities. High inter-rater reliability and agreement were determined by three independent judges. Results showed that young females had a general preference for gestalt therapy. Young and old females, but not young males, significantly preferred behavioural therapy for a specific phobia. Under forced-choice conditions the group as a whole significantly preferred gestalt therapy. No differences were found for the relationship or preference given a depressive disorder. Preference was hypothesized as a cognitive structure with potential use in therapist-client matching.

  18. [Transference and countertransference in Gestalt therapy].

    Science.gov (United States)

    Schnake Silva, A

    1981-01-01

    The aim is to demonstrate the presence of transference within Gestalt Psychotherapy, opinion not shared by many gestaltists. For this purpose she includes Freud's findings and comments on transference. She also takes into consideration Jung's and Melanie Klein's concepts on transference. The author concludes that transference is in Psychoanalysis a decisive concept in diagnosing and defining a prognosis. She refers to the fact that in Gestalt Psychotherapy the patient projects on the therapist disturbed aspects of his personallity as well as healthy ones, which determines the characteristics of the relationship. In Gestalt Therapy transference is made easy by the self-responsibility the patient has to assume in the process. Within this frame-work some of the techniques which facilitate the use of transference are mentioned: gestual observation, conscience awareness, an alliance with the healthful aspects of the patient, work in the "here-and-now", clarifying projections, switch from environmental support to inner support.

  19. An overview of quantitative approaches in Gestalt perception.

    Science.gov (United States)

    Jäkel, Frank; Singh, Manish; Wichmann, Felix A; Herzog, Michael H

    2016-09-01

    Gestalt psychology is often criticized as lacking quantitative measurements and precise mathematical models. While this is true of the early Gestalt school, today there are many quantitative approaches in Gestalt perception and the special issue of Vision Research "Quantitative Approaches in Gestalt Perception" showcases the current state-of-the-art. In this article we give an overview of these current approaches. For example, ideal observer models are one of the standard quantitative tools in vision research and there is a clear trend to try and apply this tool to Gestalt perception and thereby integrate Gestalt perception into mainstream vision research. More generally, Bayesian models, long popular in other areas of vision research, are increasingly being employed to model perceptual grouping as well. Thus, although experimental and theoretical approaches to Gestalt perception remain quite diverse, we are hopeful that these quantitative trends will pave the way for a unified theory. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Gestalt and Totality. The Case of Merleau-Ponty and Gestalt Psychology

    OpenAIRE

    Nilsen, Håvard

    2008-01-01

    Connected via Merleau-Ponty’s pupil Claude Lefort, Castoriadis followed many of Merleau-Ponty’s main theoretical themes, phenomenology and psychology. In this paper, a little acknowledged aspect of Merleau-Ponty’s philosophy is presented, specifically how he used Gestalt psychology as a crucial part of his theoretical project. Today, Gestalt psychology is usually only mentioned in introductory courses in psychology, in the chapters on perception. At the beginning of the 20th century, however,...

  1. Gestalt and Totality. The Case of Merleau-Ponty and Gestalt Psychology

    OpenAIRE

    Nilsen, Håvard

    2008-01-01

    Connected via Merleau-Ponty’s pupil Claude Lefort, Castoriadis followed many of Merleau-Ponty’s main theoretical themes, phenomenology and psychology. In this paper, a little acknowledged aspect of Merleau-Ponty’s philosophy is presented, specifically how he used Gestalt psychology as a crucial part of his theoretical project. Today, Gestalt psychology is usually only mentioned in introductory courses in psychology, in the chapters on perception. At the beginning of the 20th century, however,...

  2. Gestalt Group Dreamwork Demonstrations in Taiwan

    Science.gov (United States)

    Coven, Arnold B.

    2004-01-01

    The application of Gestalt dreamwork was explored with counselor education students and professors at two Taiwan universities. The literature indicates Asians are reluctant to disclose personal matters or to display emotions. Contrary to expectations, the Taiwanese participants readily enacted roles, were personally open, and expressed intense…

  3. A Gestalt Approach to Group Supervision

    Science.gov (United States)

    Melnick, Joseph; Fall, Marijane

    2008-01-01

    The authors define and then describe the practice of group supervision. The role of creative experiment in assisting supervisees who perceive themselves as confused, moving in circles, or immobilized is described. Fictional case examples illustrate these issues in supervision. The authors posit the "good fit" of Gestalt theory and techniques with…

  4. Bender Gestalt Performance of Normal Older Adults.

    Science.gov (United States)

    Lacks, Patricia; Storandt, Martha

    1982-01-01

    Provides normative data on the Bender Gestalt Test (BGT) with a sample of 334 normal older adults. Showed that these older adults do not perform on the BGT in a manner that can be called brain damaged. Use of the cut-off score developed with younger persons appears appropriate. (Author)

  5. A Graphic Analysis Bender Gestalt Test.

    Science.gov (United States)

    Hilgert, Larry D.

    1985-01-01

    Bender Gestalt Test data from 60 severely emotionally handicapped and 60 normal children were computer digitized and scored traditionally. Reliability results from comparison of analysis techniques favored computer approach; criterion-related validity was unsuccessful for both scoring methods; and concurrent validity results indicated limited…

  6. Junior High Norms for the Bender Gestalt.

    Science.gov (United States)

    Grow, Richard T.

    1980-01-01

    Junior high students were tested to supply normative data supporting the Bender Gestalt. Subject's performance was not significantly related to sex or occupation of the family bread winner. These variables do not have to be controlled for in norming visual motor tests at the junior high level. (Author)

  7. Gestalt Therapy and General System Theory.

    Science.gov (United States)

    Whitner, Phillip A.

    While General Systems Theory (GST) concepts appear to be applicable in explaining some of the phenomena that occur in a Gestalt Therapy group, research is needed to support this assumption. General Systems Theory may not be a group theory per se. Instead, GST may be a theory about groups. A meta-theory exists where its value and usefulness is…

  8. Reflections on Fritz Perls's Gestalt Prayer.

    Science.gov (United States)

    Dolliver, Robert H.

    1981-01-01

    Reviews the alternative forms of Fritz Perls' Gestalt Prayer, which was highly influential in the 1970s when individuality and personal rights were being explored. The prayer is subject to interpretation. Counselors should clarify for clients that ongoing relationships require a great deal of work. (JAC)

  9. A Gestalt Approach to Group Supervision

    Science.gov (United States)

    Melnick, Joseph; Fall, Marijane

    2008-01-01

    The authors define and then describe the practice of group supervision. The role of creative experiment in assisting supervisees who perceive themselves as confused, moving in circles, or immobilized is described. Fictional case examples illustrate these issues in supervision. The authors posit the "good fit" of Gestalt theory and techniques with…

  10. Gestalt Group Dreamwork Demonstrations in Taiwan

    Science.gov (United States)

    Coven, Arnold B.

    2004-01-01

    The application of Gestalt dreamwork was explored with counselor education students and professors at two Taiwan universities. The literature indicates Asians are reluctant to disclose personal matters or to display emotions. Contrary to expectations, the Taiwanese participants readily enacted roles, were personally open, and expressed intense…

  11. The role of temporo-parietal junction (TPJ) in global Gestalt perception.

    Science.gov (United States)

    Huberle, Elisabeth; Karnath, Hans-Otto

    2012-07-01

    Grouping processes enable the coherent perception of our environment. A number of brain areas has been suggested to be involved in the integration of elements into objects including early and higher visual areas along the ventral visual pathway as well as motion-processing areas of the dorsal visual pathway. However, integration not only is required for the cortical representation of individual objects, but is also essential for the perception of more complex visual scenes consisting of several different objects and/or shapes. The present fMRI experiments aimed to address such integration processes. We investigated the neural correlates underlying the global Gestalt perception of hierarchically organized stimuli that allowed parametrical degrading of the object at the global level. The comparison of intact versus disturbed perception of the global Gestalt revealed a network of cortical areas including the temporo-parietal junction (TPJ), anterior cingulate cortex and the precuneus. The TPJ location corresponds well with the areas known to be typically lesioned in stroke patients with simultanagnosia following bilateral brain damage. These patients typically show a deficit in identifying the global Gestalt of a visual scene. Further, we found the closest relation between behavioral performance and fMRI activation for the TPJ. Our data thus argue for a significant role of the TPJ in human global Gestalt perception.

  12. Gestalt compositionality and instruction-based meaning construction.

    Science.gov (United States)

    Col, Gilles; Aptekman, Jeanne; Girault, Stéphanie; Poibeau, Thierry

    2012-05-01

    We would like to propose a new model of meaning construction based on language comprehension considered as a dynamic process during which the meaning of each linguistic unit and the global meaning of the sentence are determined simultaneously. This model, which may be called "gestalt compositionality," is radically opposed to the classic compositional mechanism advocated by linguistic formalism based on the primacy of syntax. The process considers the syntactic structure of an utterance as the product of meaning construction rather than its source. The comprehension of an utterance is consequently directly based on the interaction between the different basic components of this utterance: lexical units, grammatical markers, positional relations between units, and more generally, basic "constructions" in the sense of Construction Grammar. Thus, meaning is really the result of a gestalt compositional process insomuch as the contribution of each basic component depends on the contribution of the other components present in the utterance. We show a first attempt at modeling from French and English examples.

  13. Behavior, Organization, Substance: Three Gestalts of General Systems Theory

    OpenAIRE

    De Florio, Vincenzo

    2014-01-01

    The term gestalt, when used in the context of general systems theory, assumes the value of "systemic touchstone", namely a figure of reference used to categorize the properties or qualities of a set of systems. Typical gestalts used in biology are those based on anatomical or physiological characteristics, which correspond respectively to architectural and organizational design choices in natural and artificial systems. In this paper we discuss three gestalts of general systems theory: behavi...

  14. Music, thinking, perceived motion: the emergence of Gestalt theory.

    Science.gov (United States)

    Wertheimer, Michael

    2014-05-01

    Histories of psychology typically assert that Gestalt theory began with the publication of Max Wertheimer's 1912b paper on the phi phenomenon, the compelling visual apparent motion of actually stationary stimuli. The current author discusses the origin of Gestalt theory, as told by the historical record starting with M. Wertheimer's upbringing and ending with his most recent Gestalt theories. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  15. A gestalt-experiential perspective on resistance.

    Science.gov (United States)

    Engle, David; Holiman, Marjorie

    2002-02-01

    The authors present background on the gestalt-experiential understanding of resistance, conceptualized to be either resistance to awareness or resistance to contact. The authors discuss why they do not use the term resistance and describe the phenomena as a client's self-protective attempt to avoid the anxiety necessitated by change. Such resistant behaviors occur outside a client's awareness and often result in an ambivalence or conflict about change. The authors also describe using in-session experiments as a way to engage with the client in exploring such a state of ambivalence or conflict. Finally, they respond to the case studies presented elsewhere in this issue and propose intervention strategies consistent with the gestalt-experiential perspective.

  16. Gestalt Reasoning with Conjunctions and Disjunctions.

    Science.gov (United States)

    Dumitru, Magda L; Joergensen, Gitte H

    2016-01-01

    Reasoning, solving mathematical equations, or planning written and spoken sentences all must factor in stimuli perceptual properties. Indeed, thinking processes are inspired by and subsequently fitted to concrete objects and situations. It is therefore reasonable to expect that the mental representations evoked when people solve these seemingly abstract tasks should interact with the properties of the manipulated stimuli. Here, we investigated the mental representations evoked by conjunction and disjunction expressions in language-picture matching tasks. We hypothesised that, if these representations have been derived using key Gestalt principles, reasoners should use perceptual compatibility to gauge the goodness of fit between conjunction/disjunction descriptions (e.g., the purple and/ or the green) and corresponding binary visual displays. Indeed, the results of three experimental studies demonstrate that reasoners associate conjunction descriptions with perceptually-dependent stimuli and disjunction descriptions with perceptually-independent stimuli, where visual dependency status follows the key Gestalt principles of common fate, proximity, and similarity.

  17. Brain mechanisms underlying human communication

    NARCIS (Netherlands)

    Noordzij, M.L.; Newman-Norlund, S.E.; Ruiter, J.P.A. de; Hagoort, P.; Levinson, S.C.; Toni, I.

    2009-01-01

    Human communication has been described as involving the coding-decoding of a conventional symbol system, which could be supported by parts of the human motor system (i.e. the "mirror neurons system"). However, this view does not explain how these conventions could develop in the first place. Here we

  18. Brain mechanisms underlying human communication

    NARCIS (Netherlands)

    Noordzij, Matthijs Leendert; Newman-Norlund, Sarah E.; de Ruiter, Jan Peter; Hagoort, Peter; Levinson, Stephen C.; Toni, Ivan

    2009-01-01

    Human communication has been described as involving the coding-decoding of a conventional symbol system, which could be supported by parts of the human motor system (i.e. the “mirror neurons system”). However, this view does not explain how these conventions could develop in the first place. Here we

  19. Bender Gestalt Signs as Indicants of Conceptual Impulsivity

    Science.gov (United States)

    Brannigan, Gary G.; And Others

    1978-01-01

    Sixty children were individually administered the Matching Familiar Figures Test and the Bender Gestalt Test. A significant relationship was found between errors on the Bender Gestalt Test and impulsivity. Specifically, increased or decreased loops, change in angulation, loops for circles, and circles for dots or dots for circles were all…

  20. Gestalt Therapy and Feminist Therapy: A Proposed Integration.

    Science.gov (United States)

    Enns, Carolyn Zerbe

    1987-01-01

    Offers a proposal for integrating the Gestalt goals of self-responsibility with a feminist perspective that places value on the web of relationships in women's lives and focuses attention on the environmental constraints and socialization that affect women's choices. Discusses Gestalt techniques for enhancing women's growth and examines…

  1. Gestalt Therapy and the Counseling Practicum: A Marriage.

    Science.gov (United States)

    Witchel, Robert

    This paper briefly summarizes the literature relating to the counseling practicum experience, as well as reviews the development and basic principles of Gestalt therapy. A marriage between the Gestalt therapy approach and the counseling practicum is developed as follows: "Experiential learning, the here-and-now, I-and-thou, and integrating…

  2. Active Interventions in Clinical Practice: Contributions of Gestalt Therapy.

    Science.gov (United States)

    Lammert, Marilyn; Dolan, Mary M.

    1983-01-01

    Describes two dimensions of Gestalt therapy that can enhance clinical practice--orientation to the present and active-experimental style--and examines them in relation to some traditional principles of practice. Gestalt theory offers a method of discovery that is a combination of phenomenology and behaviorism. (JAC)

  3. Alcoholism and Self-Responsibility: The Gestalt Approach.

    Science.gov (United States)

    Graceffo, Samuel A.

    1979-01-01

    The Gestalt concept of self-responsibility is the acknowledgement by the individual that he/she is the author of all behavior. The behavior of the alcoholic is contrasted with the self-responsible individual. Clinical application of Gestalt therapy techniques to alcoholism is demonstrated and discussed with case illustrations. (Author)

  4. Is Gestalt Therapy a Humanistic Form of Psychotherapy?

    Science.gov (United States)

    Bergantino, Len

    1977-01-01

    Believes the therapeutic situation that offers the greatest awareness with the least amount of dehumanization is a synthesis of the gestalt and the existential humanistic (EH) orientations. Considers the relationship and possible synthesis of the existential and gestalt positions. (Author/RK)

  5. Two Aspects of Scorer Reliability in the Bender Gestalt Test

    Science.gov (United States)

    Morsbach, Gisela; And Others

    1975-01-01

    This study investigated (a) interscorer reliability of the Bender-Gestalt Test by using more than one person to score the same test protocols; and (b) rate-rerate reliability of the Bender-Gestalt Test after a half-year interval. (Author)

  6. New studies of adults' responses to the Bender Gestalt.

    Science.gov (United States)

    Murray, J B

    2001-02-01

    The Bender-Gestalt test originated in 1936 with Lauretta Bender for evaluating perceptual and motor development of children 4 to 11 yr. old. Koppitz (1964) developed a scoring system for the test. Lacks (1984) contributed normative data for testing adults. Seven studies since Lacks' which have contributed to normative data of adults' responses to the Bender-Gestalt are reviewed here.

  7. Grouping and Emergent Features in Vision: Toward a Theory of Basic Gestalts

    Science.gov (United States)

    Pomerantz, James R.; Portillo, Mary C.

    2011-01-01

    Gestalt phenomena are often so powerful that mere demonstrations can confirm their existence, but Gestalts have proven hard to define and measure. Here we outline a theory of basic Gestalts (TBG) that defines Gestalts as emergent features (EFs). The logic relies on discovering wholes that are more discriminable than are the parts from which they…

  8. Grouping and Emergent Features in Vision: Toward a Theory of Basic Gestalts

    Science.gov (United States)

    Pomerantz, James R.; Portillo, Mary C.

    2011-01-01

    Gestalt phenomena are often so powerful that mere demonstrations can confirm their existence, but Gestalts have proven hard to define and measure. Here we outline a theory of basic Gestalts (TBG) that defines Gestalts as emergent features (EFs). The logic relies on discovering wholes that are more discriminable than are the parts from which they…

  9. Gestalt Therapy and Cognitive Therapy - Contrasts or Complementarities?

    DEFF Research Database (Denmark)

    Tønnesvang, Jan; Sommer, Ulla; Hammink, James

    2010-01-01

    The article investigates the relationship between crucial concepts and understandings in gestalt therapy and cognitive therapy aiming at discussing if and how they can be mutually enriching when considered as complementary parts in a more encompassing integrative therapeutic approach. It is argued...... that gestalt therapy, defined as a fieldtheoretical approach to the study of gestalt formation process, can complement the schema-based understanding and practice in cognitive therapy. The clinical benefits from a complementary view of the two approaches will be a wider scope of awareness toward individual...... between fundamental awareness work in gestalt therapy and the tendency within cognitive therapy toward incorporating mindfulness as a therapeutic tool. In the conclusion of the article, additional complementary points between the two approaches are outlined. Keywords: integrative therapy, gestalt...

  10. Gestalt psychology: the forgotten paradigm in abnormal psychology.

    Science.gov (United States)

    Silverstein, Steven M; Uhlhaas, Peter J

    2004-01-01

    Gestalt views of psychopathology are almost completely ignored in mainstream psychology and psychiatry. However, a review of available evidence indicates a remarkable consistency between these views and current data from experimental psychopathology and cognitive neuroscience. This consistency is especially pronounced in the area of schizophrenia. In addition, there is a convergence of cognitive and neurobiological evidence regarding the validity of early Gestalt views of both normal brain-behavior relationships and disordered ones, as in schizophrenia. This article reviews some contributions of Gestalt psychology regarding schizophrenia and examines these views in light of more recent findings from cognitive psychology, cognitive neuroscience, and experimental psychopathology. We conclude that Gestalt theory is a viable theoretical framework from which to understand schizophrenia. Specifically, it appears that a breakdown of Gestalt organizational processes may characterize both the cognitive and the brain processes in schizophrenia.

  11. [Ludwik Fleck and the Gestalt psychology of his time].

    Science.gov (United States)

    Zittel, Claus

    2014-01-01

    The notion of 'Gestalt' plays a prominent role in Ludwik Fleck's theory of thought styles. This paper scrutinizes how Fleck adopted the concepts and even methods of Gestalt psychology that he sometimes vaguely refers to. Systematically comparing the argumentation and theoretical outlines of Fleck's social theory of perception and the principles of some Gestalt theories, this article will show and discuss their similarities and fundamental differences. According to Fleck, both science and individual perception rest on social actions and cultural traditions. In particular, Fleck emphasized the relevance of the common language and collective meanings for the shaping of objects according to the thought style of a scientific collective. In contrast to the principles of Gestalt theories, in Fleck's view not only the perception, but also the constitution of scientific objects and even the'laws' of perception depend on social and cultural constructions of reality. That leads him to a particular theory of Gestalt perception

  12. Gestalt Algebra—A Proposal for the Formalization of Gestalt Perception and Rendering

    Directory of Open Access Journals (Sweden)

    Eckart Michaelsen

    2014-07-01

    Full Text Available Gestalt Algebra gives a formal structure suitable for describing complex patterns in the image plain. This can be useful for recognizing hidden structure in images. The work at hand refers to the laws of perceptual psychology. A manifold called the Gestalt Domain is defined. Next to the position in 2D it also contains an orientation and a scale component. Algebraic operations on it are given for mirror symmetry as well as organization into rows. Additionally the Gestalt Domain contains an assessment component, and all the meaning of the operations implementing the Gestalt-laws is realized in the functions giving this component. The operation for mirror symmetry is binary, combining two parts into one aggregate as usual in standard algebra. The operation for organization into rows, however, combines n parts into an aggregate, where n may well be more than two. This is algebra in its more general sense. For recognition, primitives are extracted from digital raster images by Lowe’s Scale Invariant Feature Transform (SIFT. Lowe’s key-point descriptors can also be utilized. Experiments are reported with a set of images put forth for the Computer Vision and Pattern Recognition Workshops (CVPR 2013 symmetry contest.

  13. Qi Gong exercises and Feldenkrais method from the perspective of Gestalt concept and humanistic psychology.

    Science.gov (United States)

    Posadzki, Paul; Stöckl, Andrea; Mucha, Dariusz

    2010-07-01

    This study describes two similar approaches to human movement: Qi Gong exercises and the Feldenkrais method. These systems are investigated in terms of Gestalt concepts and humanistic psychology. Moshe Feldenkrais created the concept known as Awareness Through Movement. This concept assumes that by becoming more aware of one's movements, one functions at a higher level. In similar ways to those using the Feldenkrais method, individuals may become more aware of their own movements by performing Qi Gong exercises: A therapeutic modality that facilitates mind-body integration. Qi Gong exercises commonly lead to increased personal awareness accompained by enhanced quality, fluency and smoothness of movement. These two methods of movement therapies are explored in terms of their relations with Gestalt concept and humanistic psychology. (c) 2008. Published by Elsevier Ltd. All rights reserved.

  14. Mechanism of human tooth eruption

    DEFF Research Database (Denmark)

    Kjær, Inger

    2014-01-01

    discussed in the introduction. Human studies, mainly clinical and radiological, have focused on normal eruption and gender differences. Why a tooth begins eruption and what enables it to move eruptively and later to end these eruptive movements is not known. Pathological eruption courses contribute...

  15. [Gestalt therapy, extension of psychoanalysis (author's transl)].

    Science.gov (United States)

    Moreau, A

    1980-01-01

    Gestalt therapy extends considerably psychoanalysis. 1. Transfer in psychoanalysis allows to work on the disturbed relations which the patient transfers onto his analyst, relations created by the parents and repeated now. The extended transfer in a therapeutic group of life allows to work on the fact that the patient recreates here and now the difficulties he encounters in life. 2. The game of the analyst and the encounter show that beyond transfer and projection, a real encounter may take place, a precious means to create life here and now. 3. The difference between individual therapy and group-therapy is about this: the former is centered on illness, the latter on life; the former helps to understand, the latter to live; the individual talks about facts from the past and from elsewhere and the group lives "here and now", which allows to test feelings, a powerful source of life. 4. A session of group-therapy, as developed here, allows to see how one can find a response to a need or avoid to find a response to it. 5. A comparison-table between psycho-analysis and gestalt shows the difference of method, diagnosis, therapeutic process, therapeutist's attitude and of the position of the patient. 6. Psycho-analysis is perhaps a relay after religion? Several elements make us believe this: tension in contacts, ritual, authority, protection, neutrality, guilty making. 7. To contest or contest one-self has helped me to compare the contester with the psycho-analyst: both contest society, but they don't change their behavior. The gestalt-therapeutist is in a way like a hippie: though contesting society, he brings a change to his way of life, while being closer to life.

  16. Mechanisms for Human Spatial Competence

    Science.gov (United States)

    2007-01-01

    experience. To take a famous example from Stevens & Coupe [43], when studying a map of the United States, San Diego will tend to be encoded with respect to...Relations. Cognitive Psychology 18, 87–121 (1986) 43. Stevens , A., Coupe, P.: Distortions in Judged Spatial Relations. Cognitive Psychology 10, 422...Model of Human Attentional Networks. Cognitive Systems Research 5, 119–134 (2004) 60. Finke, R.A., Pinker , S., Farah, M.: Reinterpreting Visual

  17. Getrieben oder Gestalter in Marketing und Vertrieb?

    OpenAIRE

    Belz, Christian; Lee, You-Cheong

    2014-01-01

    Fühlen sich die Manager in Marketing und Vertrieb als Gestalter oder Getriebene? Was tun Führungskräfte in Marketing und Vertrieb wirklich und wo setzen sie Schwerpunkte in ihrer Aufgabe? Wie nutzen sie ihre Zeit? Diese Fragen beantworten wir, gestützt auf eine Online-Erhebung im 1. Quartal 2013. 135 Führungskräfte beteiligten sich, davon waren 38,5 Prozent für Marketing, 23 Prozent für Vertrieb und 38,5 Prozent für beide Funktionen zuständig. Das Ergebnis: Verantwortliche in Marketin...

  18. Undrestanding of the 'self' in Gestalt therapy

    Directory of Open Access Journals (Sweden)

    Rudi Kotnik

    2001-09-01

    Full Text Available In Gestalt therapy theory there is an emphasis on understanding of the 'self' as a process (as opposed to structure. The paper examines the relationship between process and structure in understanding of the 'self'. For this purpose a brief review of other theoretical approaches is presented in the introduction, while the main discussion is followed by illustrations and implications for clinical practice. The result of focusing on process as here and now, rather than on content, is awareness of the processes in the therapeutic relationship. And a change in a therapeutic relationship brings up a possibilities for changes in a real-life situations.

  19. Gestalt-binding of tropomyosin on actin during thin filament activation.

    Science.gov (United States)

    Lehman, William; Orzechowski, Marek; Li, Xiaochuan Edward; Fischer, Stefan; Raunser, Stefan

    2013-08-01

    Our thesis is that thin filament function can only be fully understood and muscle regulation then elucidated if atomic structures of the thin filament are available to reveal the positions of tropomyosin on actin in all physiological states. After all, it is tropomyosin influenced by troponin that regulates myosin-crossbridge cycling on actin and therefore controls contraction in all muscles. In addition, we maintain that a complete appreciation of thin filament activation also requires that the mechanical properties of tropomyosin itself are recognized and then related to the effect of myosin-association on actin. Taking the Gestalt-binding of tropomyosin into account, coupled with our electron microscopy structures and computational chemistry, we propose a comprehensive mechanism for tropomyosin regulatory movement over the actin filament surface that explains the cooperative muscle activation process. In fact, well-known point mutations of critical amino acids on the actin-tropomyosin binding interface disrupt Gestalt-binding and are associated with a number of inherited myopathies. Moreover, dysregulation of tropomyosin may also be a factor that interferes with the gatekeeping operation of non-muscle tropomyosin in the controlling interactions of a wide variety of cellular actin-binding proteins. The clinical relevance of Gestalt-binding is discussed in articles by the Marston and the Gunning groups in this special journal issue devoted to the impact of tropomyosin on biological systems.

  20. Gestalt principle use in college students, children with autism, toddlers (Homo sapiens), and cotton top tamarins (Saguinus oedipus).

    Science.gov (United States)

    Neiworth, Julie J; Whillock, Katherine M; Kim, Seo Hyun; Greenberg, Julia R; Jones, Katherine B; Patel, Anushka R; Steefel-Moore, David L; Shaw, Allyson J; Rupert, Deborah D; Gauer, Jacqueline L; Kudura, Aisha G

    2014-05-01

    The use of Gestalt principles of proximity, similarity, and closure to recognize objects by configural superiority was examined in college students, low- and high-functioning children with autism, toddlers, and adult cotton top tamarin monkeys. At issue was whether the monkeys showed differences from humans in perceptual processing and whether they showed any similarities with clinical or developmental groups. The method required a pointing response to discriminate an odd item in a 4-item visual display. All subjects were trained to a high accuracy to point to the odd item before being tested with graphic stimuli that differentiated feature changes based on configural superiority. The results were that college students and high-functioning children with autism responded faster and more accurately to trials in which the odd item was easily noticed by the use of Gestalt principles and configural superiority. Toddlers also responded more accurately to the Gestalt trials, but without being faster at making the response. Low-functioning children with autism and tamarins showed no advantage to Gestalt trials but exhibited different processing styles. The implications of these findings to track the evolution of human perception and to develop a primate model for the perceptual deficits of autism are discussed. ©2014 APA, all rights reserved.

  1. Brain mechanisms underlying human communication.

    Science.gov (United States)

    Noordzij, Matthijs L; Newman-Norlund, Sarah E; de Ruiter, Jan Peter; Hagoort, Peter; Levinson, Stephen C; Toni, Ivan

    2009-01-01

    Human communication has been described as involving the coding-decoding of a conventional symbol system, which could be supported by parts of the human motor system (i.e. the "mirror neurons system"). However, this view does not explain how these conventions could develop in the first place. Here we target the neglected but crucial issue of how people organize their non-verbal behavior to communicate a given intention without pre-established conventions. We have measured behavioral and brain responses in pairs of subjects during communicative exchanges occurring in a real, interactive, on-line social context. In two fMRI studies, we found robust evidence that planning new communicative actions (by a sender) and recognizing the communicative intention of the same actions (by a receiver) relied on spatially overlapping portions of their brains (the right posterior superior temporal sulcus). The response of this region was lateralized to the right hemisphere, modulated by the ambiguity in meaning of the communicative acts, but not by their sensorimotor complexity. These results indicate that the sender of a communicative signal uses his own intention recognition system to make a prediction of the intention recognition performed by the receiver. This finding supports the notion that our communicative abilities are distinct from both sensorimotor processes and language abilities.

  2. Brain mechanisms underlying human communication

    Directory of Open Access Journals (Sweden)

    Matthijs L Noordzij

    2009-07-01

    Full Text Available Human communication has been described as involving the coding-decoding of a conventional symbol system, which could be supported by parts of the human motor system (i.e. the “mirror neurons system”. However, this view does not explain how these conventions could develop in the first place. Here we target the neglected but crucial issue of how people organize their non-verbal behavior to communicate a given intention without pre-established conventions. We have measured behavioral and brain responses in pairs of subjects during communicative exchanges occurring in a real, interactive, on-line social context. In two fMRI studies, we found robust evidence that planning new communicative actions (by a sender and recognizing the communicative intention of the same actions (by a receiver relied on spatially overlapping portions of their brains (the right posterior superior temporal sulcus. The response of this region was lateralized to the right hemisphere, modulated by the ambiguity in meaning of the communicative acts, but not by their sensorimotor complexity. These results indicate that the sender of a communicative signal uses his own intention recognition system to make a prediction of the intention recognition performed by the receiver. This finding supports the notion that our communicative abilities are distinct from both sensorimotor processes and language abilities.

  3. Gestalt principles in the control of motor action.

    Science.gov (United States)

    Klapp, Stuart T; Jagacinski, Richard J

    2011-05-01

    We argue that 4 fundamental gestalt phenomena in perception apply to the control of motor action. First, a motor gestalt, like a perceptual gestalt, is holistic in the sense that it is processed as a single unit. This notion is consistent with reaction time results indicating that all gestures for a brief unit of action must be programmed prior to initiation of any part of the movement. Additional reaction time results related to initiation of longer responses are consistent with processing in terms of a sequence of indivisible motor gestalts. Some actions (e.g., many involving coordination of the hands) can be carried out effectively only if represented as a unitary gestalt. Second, a perceptual gestalt is independent of specific sensory receptors, as evidenced by perceptual constancy. In a similar manner a motor gestalt can be represented independently of specific muscular effectors, thereby allowing motor constancy. Third, just as a perceptual pattern (e.g., a Necker cube) is exclusively structured into only 1 of its possible configurations at any moment in time, processing prior to action is limited to 1 motor gestalt. Fourth, grouping in apparent motion leads to stream segregation in visual and auditory perception; this segregation is present in motor action and is dependent on the temporal rate. We discuss congruence of gestalt phenomena across perception and motor action (a) in relation to a unitary perceptual-motor code, (b) with respect to differences in the role of awareness, and (c) in conjunction with separate neural pathways for conscious perception and motor control.

  4. A Gestalt perspective on working with people with HIV disease.

    Science.gov (United States)

    Sabar, S

    1997-03-01

    Four aspects of Gestalt practice that are particularly relevant to HIV-related therapy are explored: the client-therapist relationship, the phenomenonological method, awareness as the goal of therapy, and experiments and role playing. Applying the Gestalt ideals of self-regulation, wholeness, and growth to a person with HIV is vital to counteract the patient's loss of immune function. The Gestalt experience cycle, defined as a model of how people identify their needs and then set out to meet those needs, is a useful paradigm in HIV-related therapy.

  5. Gestalt imagery: A critical factor in language comprehension.

    Science.gov (United States)

    Bell, N

    1991-01-01

    Gestalt imagery-the ability to create imaged wholes-is a critical factor in oral and written language comprehension. Despite good decoding, good vocabulary, and adequate background experiences, many individuals experience weak gestalt imagery, thus processing "parts" rather than "wholes," from verbal stimuli, spoken or written. This contributes to a Language Comprehension Disorder that may be accompanied by a commonality of symptoms: weak reading comprehension, weak oral language comprehension, weak oral language expression, weak written language expression, difficulty following directions, and a weak sense of humor. Sequential stimulation using an inquiry technique develops gestalt imagery and results in significant improvement in reading comprehension.

  6. Gestalt and Totality. The Case of Merleau-Ponty and Gestalt Psychology

    Directory of Open Access Journals (Sweden)

    Nilsen, Håvard

    2008-12-01

    Full Text Available Connected via Merleau-Ponty’s pupil Claude Lefort, Castoriadis followed many of Merleau-Ponty’s main theoretical themes, phenomenology and psychology. In this paper, a little acknowledged aspect of Merleau-Ponty’s philosophy is presented, specifically how he used Gestalt psychology as a crucial part of his theoretical project. Today, Gestalt psychology is usually only mentioned in introductory courses in psychology, in the chapters on perception. At the beginning of the 20th century, however, they were widely debated as an attempt at transforming positivism and scientific epistemology. The aim of this paper is to show a largely forgotten, but significant source of influence in intellectual history and 20th century philosophy.

  7. Use of Gestalt Therapy Within a Drug Treatment Program.

    Science.gov (United States)

    Sideroff, Stephen I.

    1979-01-01

    Presents a Gestalt therapeutic approach that has shown promise within a drug treatment program. The major issues discussed include the acquisition of self-support, taking responsibility, dealing with anxiety, contact, and the expression of pent-up feelings. (Author)

  8. Gestalt psychotherapy in the outpatient treatment of borderline ...

    African Journals Online (AJOL)

    the use of Gestalt psychotherapy in the treatment of BPD patients. The authors ... psychological tests showed difficulties in social communication and adjustment, as .... impairments in reasoning, personality, movement, speech, social graces ...

  9. Gestalt Effects in Visual Working Memory.

    Science.gov (United States)

    Kałamała, Patrycja; Sadowska, Aleksandra; Ordziniak, Wawrzyniec; Chuderski, Adam

    2017-01-01

    Four experiments investigated whether conforming to Gestalt principles, well known to drive visual perception, also facilitates the active maintenance of information in visual working memory (VWM). We used the change detection task, which required the memorization of visual patterns composed of several shapes. We observed no effects of symmetry of visual patterns on VWM performance. However, there was a moderate positive effect when a particular shape that was probed matched the shape of the whole pattern (the whole-part similarity effect). Data support the models assuming that VWM encodes not only particular objects of the perceptual scene but also the spatial relations between them (the ensemble representation). The ensemble representation may prime objects similar to its shape and thereby boost access to them. In contrast, the null effect of symmetry relates the fact that this very feature of an ensemble does not yield any useful additional information for VWM.

  10. Joint action: Neurocognitive mechanisms supporting human interaction

    NARCIS (Netherlands)

    Bekkering, H.; Bruijn, E.R.A. de; Cuijpers, R.H.; Newman-Norlund, R.D.; Schie, H.T. van; Meulenbroek, R.G.J.

    2009-01-01

    Humans are experts in cooperating with each other when trying to accomplish tasks they cannot achieve alone. Recent studies of joint action have shown that when performing tasks together people strongly rely on the neurocognitive mechanisms that they also use when performing actions individually, th

  11. Human Error Mechanisms in Complex Work Environments

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1988-01-01

    will account for most of the action errors observed. In addition, error mechanisms appear to be intimately related to the development of high skill and know-how in a complex work context. This relationship between errors and human adaptation is discussed in detail for individuals and organisations...

  12. The Impact of Gestalt Group Psychotherapy on Parents' Perceptions of Children Identified as Problematic.

    Science.gov (United States)

    Little, Linda F.

    Gestalt therapy respects parents' perceptions of their children and does not attempt to train parents to become therapists for their children. To examine the impact of Gestalt group psychotherapy on parents' perceptions of children identified as problematic, an experimental group of 10 parents participated in 10 2-hour Gestalt sessions. A group of…

  13. Reassessment of Inferring Personality Traits from Bender-Gestalt Drawing Styles.

    Science.gov (United States)

    Holmes, Cooper B.; And Others

    1984-01-01

    Assessed patients with closure difficulty on the Bender-Gestalt (N=50) and patients with edging tendencies on the Bender-Gestalt (N=50) for possible personality traits associated with those drawing styles. Results did not support using clients' Bender-Gestalt drawing style as a basis for inferring personality traits. (LLL)

  14. How color, regularity, and good Gestalt determine backward masking.

    Science.gov (United States)

    Sayim, Bilge; Manassi, Mauro; Herzog, Michael

    2014-06-18

    The strength of visual backward masking depends on the stimulus onset asynchrony (SOA) between target and mask. Recently, it was shown that the conjoint spatial layout of target and mask is as crucial as SOA. Particularly, masking strength depends on whether target and mask group with each other. The same is true in crowding where the global spatial layout of the flankers and target-flanker grouping determine crowding strength. Here, we presented a vernier target followed by different flanker configurations at varying SOAs. Similar to crowding, masking of a red vernier target was strongly reduced for arrays of 10 green compared with 10 red flanking lines. Unlike crowding, single green lines flanking the red vernier showed strong masking. Irregularly arranged flanking lines yielded stronger masking than did regularly arranged lines, again similar to crowding. While cuboid flankers reduced crowding compared with single lines, this was not the case in masking. We propose that, first, masking is reduced when the flankers are part of a larger spatial structure. Second, spatial factors counteract color differences between the target and the flankers. Third, complex Gestalts, such as cuboids, seem to need longer processing times to show ungrouping effects as observed in crowding. Strong parallels between masking and crowding suggest similar underlying mechanism; however, temporal factors in masking additionally modulate performance, acting as an additional grouping cue. © 2014 ARVO.

  15. Gestalt Therapy and the Therapeutic Presence of Fritz Perls: An Interview with Claudio Naranjo

    Directory of Open Access Journals (Sweden)

    Iván Ramírez Calderón

    2011-01-01

    Full Text Available As exceptional witness and participant in the origin and development of the Gestalt therapy, Claudio Naranjo considers in this interview the cha- racteristics of this form of therapy, doing so from his work and his personal encounter with the man and the therapeutic figure of Fritz Perls. In the interview the experiential base and the therapeutic change elements are established, along with the therapeutic attitude, and the holistic conception of the person; also, the contrasts among academic psychology, the spiritual dimension of human beings, and the therapist’s intuition in the help rela- tionship are highlighted.

  16. The mechanism of humanization of globalistionion consciousness of humanity

    Directory of Open Access Journals (Sweden)

    R. M. Kolisnichenko

    2016-08-01

    Humanistic type of globalistion consciousness involves improving operations globalistion institutions of socialization to the level necessary for effective humanization of a globalistion public consciousness. Representatives of the humanistic type of globalistion consciousness consider it necessary to increase the volume of international aid allocated to media development, cultural industry, education in developing countries, the global establishment of democracy, the introduction of the world Court of Human Rights, to ensure the independence of political parties from the harmful influence of the business elite, the active involvement of institutions globalistion socialization to the targeted formation humanistic globalistion consciousness of the world population. It proved the urgent need for a global revision of the strategic approaches to qualitative development of globalistion institutions of socialization in the world to create an effective mechanism for the humanization of a globalistion consciousness of humanity.

  17. Wittgenstein on Köhler and Gestalt psychology: a critique.

    Science.gov (United States)

    Pastore, N

    1991-10-01

    Wittgenstein's objections to Köhler and gestalt psychology are critically examined. Principal features of Köhler's Gestalt Psychology are discussed that are relevant to Wittgenstein's views. They include Köhler's concepts of "subjective" and "objective" experiences, "sensory organization," and "empiristic theory." Wittgenstein's objections, which focus on the concept of sensory organization, are examined. Wittgenstein employs the term "aspect," which is derived from the findings of gestalt psychology, as a replacement for Köhler's term "sensory organization." After tracing his uses of aspect, it is shown that aspect is a superordinate entity distinct from 'sensory content' (colors and shapes). This dualism of aspect and sensory content is of the same kind that prevailed in the empiristic theory of visual perception. Wittgenstein's adherence to the empiristic theory is discussed. Finally, the difference between Wittgenstein's aspect and Köhler's sensory organization is examined.

  18. Local and Global Gestalt Laws: A Neurally Based Spectral Approach.

    Science.gov (United States)

    Favali, Marta; Citti, Giovanna; Sarti, Alessandro

    2017-02-01

    This letter presents a mathematical model of figure-ground articulation that takes into account both local and global gestalt laws and is compatible with the functional architecture of the primary visual cortex (V1). The local gestalt law of good continuation is described by means of suitable connectivity kernels that are derived from Lie group theory and quantitatively compared with long-range connectivity in V1. Global gestalt constraints are then introduced in terms of spectral analysis of a connectivity matrix derived from these kernels. This analysis performs grouping of local features and individuates perceptual units with the highest salience. Numerical simulations are performed, and results are obtained by applying the technique to a number of stimuli.

  19. [A meta-analysis of the effectiveness of gestalt therapy].

    Science.gov (United States)

    Bretz, H J; Heekerens, H P; Schmitz, B

    1994-01-01

    This metaanalytical assessment of evaluation research in the field of Gestalt therapy has been conducted on the basis of 38 studies which took place between 1970 and 1986. Its scope is substantially broader than the metaanalysis of Smith, Glass and Miller (1980) or the secondary analysis of Grawe's Berner Workgroup documented in Forschungsgutachten zu Fragen eines Psychotherapeutengesetzes (1991). The results indicate Gestalt therapy to be an effective psychotherapeutic treatment which is not inferior to other comparable methods of treatment. No definitive statement can be made concerning differential indication, individual therapy setting or long-term measures.

  20. An outcome study of gestalt-oriented growth workshops.

    Science.gov (United States)

    Leung, Grace Suk Man; Leung, Timothy Yuk Ki; Ng, Monica Lai Tuen

    2013-01-01

    Compared to other intervention modalities, there are relatively few outcome studies of gestalt therapy. This study aimed to address this gap by evaluating the therapeutic effects of four gestalt-oriented group workshops designed to enhance well-being in professionals trained as social workers, counselors, and psychologists. The results of this preliminary, uncontrolled study indicated that the 55 participants had better emotional well-being and experienced a heightened sense of hope following the workshops. The factors leading to these positive outcomes are discussed.

  1. Statistical Mechanical Approach to Human Language

    CERN Document Server

    Kosmidis, K; Argyrakis, P; Kosmidis, Kosmas; Kalampokis, Alkiviadis; Argyrakis, Panos

    2005-01-01

    We use the formulation of equilibrium statistical mechanics in order to study some important characteristics of language. Using a simple expression for the Hamiltonian of a language system, which is directly implied by the Zipf law, we are able to explain several characteristic features of human language that seem completely unrelated, such as the universality of the Zipf exponent, the vocabulary size of children, the reduced communication abilities of people suffering from schizophrenia, etc. While several explanations are necessarily only qualitative at this stage, we have, nevertheless, been able to derive a formula for the vocabulary size of children as a function of age, which agrees rather well with experimental data.

  2. Human factors assessment mechanical compression tools

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, C. [BC Research Inc., Vancouver, BC (Canada)

    1999-09-01

    The design and use of mechanical compression tools in electrical distribution functions were examined from the point of view of effects of design and use of tools on human operators. Various alternative tools such as manual compression tools, battery operated tools, wedge pressure tools, hydraulic tools, and insulating piercing connectors were also examined for purposes of comparison. Results of the comparative assessment were summarized and a tool satisfaction ratings table was produced for Burndy MD6, Huskie-Robo (REC 258) and Ampact (small) tools, rating level of effort, fatigue experienced, tool mass, force required to crimp, ease of use, comfort while using the tool, maneuverability, and overall satisfaction. Both the battery operated tool as well as the wedge pressure tool have been found to have ergonomic advantages over the mechanical compression tool.

  3. Human Structural Variation: Mechanisms of Chromosome Rearrangements.

    Science.gov (United States)

    Weckselblatt, Brooke; Rudd, M Katharine

    2015-10-01

    Chromosome structural variation (SV) is a normal part of variation in the human genome, but some classes of SV can cause neurodevelopmental disorders. Analysis of the DNA sequence at SV breakpoints can reveal mutational mechanisms and risk factors for chromosome rearrangement. Large-scale SV breakpoint studies have become possible recently owing to advances in next-generation sequencing (NGS) including whole-genome sequencing (WGS). These findings have shed light on complex forms of SV such as triplications, inverted duplications, insertional translocations, and chromothripsis. Sequence-level breakpoint data resolve SV structure and determine how genes are disrupted, fused, and/or misregulated by breakpoints. Recent improvements in breakpoint sequencing have also revealed non-allelic homologous recombination (NAHR) between paralogous long interspersed nuclear element (LINE) or human endogenous retrovirus (HERV) repeats as a cause of deletions, duplications, and translocations. This review covers the genomic organization of simple and complex constitutional SVs, as well as the molecular mechanisms of their formation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. The Statistical Mechanics of Human Weight Change

    CERN Document Server

    Lang, John C; Abrams, Daniel M

    2016-01-01

    In the context of the global obesity epidemic, it is important to know who becomes obese and why. However, the processes that determine the changing shape of Body Mass Index (BMI) distributions in high-income societies are not well-understood. Here we establish the statistical mechanics of human weight change, providing a fundamental new understanding of human weight distributions. By compiling and analysing the largest data set so far of year-over-year BMI changes, we find, strikingly, that heavy people on average strongly decrease their weight year-over-year, and light people increase their weight. This drift towards the centre of the BMI distribution is balanced by diffusion resulting from random fluctuations in diet and physical activity that are, notably, proportional in size to BMI. We formulate a stochastic mathematical model for BMI dynamics, deriving a theoretical shape for the BMI distribution and offering a mechanism to explain the ongoing right-skewed broadening of BMI distributions over time. The...

  5. Gestalt-A Learning Theory for Graphic Design Education

    Science.gov (United States)

    Jackson, Ian

    2008-01-01

    This article will begin by seeking to define the notion of learning "by, through" and "from" experience. A linkage will then be established between these notions of experiences and gestalt theory. This will be explored within a subject specific context of graphic design. Links will be highlighted between the inherent nature of graphic design and…

  6. Bender Gestalt Recall: Memory Measure or Intelligence Estimate?

    Science.gov (United States)

    Armentrout, James A.

    1976-01-01

    WAIS subtset standard scores, IQ scores, and factorial deviation quotients were correlated with Bender Gestalt recall scores for 111 vocational rehabilitation clients. Results found that the Bender recall task could not classify Ss as to general intelligence level with greater accuracy than could be obtained with the WAIS Vocabulary subtest alone.…

  7. Factor- Analytic Study of Performance on the Bender-Gestalt

    Science.gov (United States)

    Haynes, Jack R.

    1970-01-01

    College students were given the 16 Personality Factor Questionnaire, the Guilford Zimmerman Spatial Orientation and Spatial Visualization Tests, and the Bender Gestalt. Analyses revealed that personality characteristics were related to Bender performance and that the Bender was not measuring a unitary dimension of behavior. (Author)

  8. Sociocultural Factors and Bender Visual Motor Gestalt Performance.

    Science.gov (United States)

    Sapp, Gary L.

    The Bender Visual Motor Gestalt Test (BG), a test of visual-motor integration, is a screening device used to investigate school-related factors that may produce poor academic achievement and learning disabilities. Because BG test stimuli are not obviously related to classroom content, and because BG scores are frequently offered as evidence of…

  9. The Application of Gestalt Principles in Classroom Teaching

    Science.gov (United States)

    Phillips, Mark

    1976-01-01

    Discusses the application of principles and techniques derived from Gestalt therapy to education. Initial investigations of the results of these applications have noted significant benefits to both teachers and students, including personal control, self-knowledge and self-esteem. For journal availability, see SO 504 730. (Author/DB)

  10. Gestalt Therapy with Females Involved in Intimate Violence.

    Science.gov (United States)

    Little, Linda F.

    This paper notes recent evidence suggesting that couples characterized by violent interactions respond best to therapy when seen first in individual therapy sessions. Clinicians are then presented with a Gestalt therapy approach to intervening in cases of intimate violence that goes beyond crisis intervention. The focus is on the female's roles in…

  11. Predicting Benefit from a Gestalt Therapy Marathon Workshop.

    Science.gov (United States)

    Healy, James; Dowd, E. Thomas

    1981-01-01

    Tested the utility of the Personal Orientation Inventory (POI), the Myers-Briggs Type Indicator, and the Girona Affect Scale in predicting the outcomes of a marathon Gestalt therapy workshop. Signigicant predictive equations were generated that use the POI to predict gains on the Girona Affect Scale. (Author/RC)

  12. A Gestalt Point of View on Facilitating Growth in Counseling

    Science.gov (United States)

    Harman, Robert L.

    1975-01-01

    If counselors are to be facilitators of client growth, it would seem essentail that they become familiar with the concept of growth and ways to facilitate it. The author defines growth from a gestalt therapy point of view and provides techniques and examples of ways to facilitate client growth. (Author)

  13. The Importance of Group Process in Gestalt Therapy.

    Science.gov (United States)

    Korb, Margaret Patton; Themis, Sharon

    1980-01-01

    Discusses the Gestalt therapy group process and its roots in theory and therapeutic orientation. Indicates that the process itself, particularly the role of the therapist, is a key factor in the intensity and power of the group experience for the participants. (Author)

  14. An Annotated Bibliography of the Gestalt Methods, Techniques, and Therapy

    Science.gov (United States)

    Prewitt-Diaz, Joseph O.

    The purpose of this annotated bibliography is to provide the reader with a guide to relevant research in the area of Gestalt therapy, techniques, and methods. The majority of the references are journal articles written within the last 5 years or documents easily obtained through interlibrary loans from local libraries. These references were…

  15. Guidelines for Training in Advanced Gestalt Therapy Skills.

    Science.gov (United States)

    Holiman, Marjorie; Engle, David

    1989-01-01

    Describes guidelines for gestalt training emphasizing observation of novice and expert therapists, opportunities to practice skills, and procedures to provide trainees with immediate feedback. Claims three methods of evaluation are useful to trainees: publicly monitoring progress; increasing specificity of feedback; and helping trainees to…

  16. Intrapersonal and Interpersonal Models: Blending Gestalt and Family Therapies

    Science.gov (United States)

    Hatcher, Chris

    1978-01-01

    Family therapy is primarily focused upon interpersonal or transactional issues. Gestalt therapy is particularly well suited for short term work on intrapersonal and boundary issues. This paper shows how the selective integration of the two approaches provides a significant, new dimension in the development of family therapy. (Author)

  17. A Taxonomic Approach to the Gestalt Theory of Perls

    Science.gov (United States)

    Raming, Henry E.; Frey, David H.

    1974-01-01

    This study applied content analysis and cluster analysis to the ideas of Fritz Perls to develop a taxonomy of Gestalt processes and goals. Summaries of the typal groups or clusters were written and the implications of taxonomic research in counseling discussed. (Author)

  18. To What Extent Do Gestalt Grouping Principles Influence Tactile Perception?

    Science.gov (United States)

    Gallace, Alberto; Spence, Charles

    2011-01-01

    Since their formulation by the Gestalt movement more than a century ago, the principles of perceptual grouping have primarily been investigated in the visual modality and, to a lesser extent, in the auditory modality. The present review addresses the question of whether the same grouping principles also affect the perception of tactile stimuli.…

  19. Gestalt-A Learning Theory for Graphic Design Education

    Science.gov (United States)

    Jackson, Ian

    2008-01-01

    This article will begin by seeking to define the notion of learning "by, through" and "from" experience. A linkage will then be established between these notions of experiences and gestalt theory. This will be explored within a subject specific context of graphic design. Links will be highlighted between the inherent nature of graphic design and…

  20. Gestalt therapy and cognitive therapy--contrasts or complementarities?

    Science.gov (United States)

    Tønnesvang, Jan; Sommer, Ulla; Hammink, James; Sonne, Mikael

    2010-12-01

    The article investigates the relationship between crucial concepts and understandings in gestalt therapy and cognitive therapy aiming at discussing if and how they can be mutually enriching when considered as complementary parts in a more encompassing integrative therapeutic approach. It is argued that gestalt therapy, defined as a field-theoretical approach to the study of gestalt formation process, can complement the schema-based understanding and practice in cognitive therapy. The clinical benefits from a complementary view of the two approaches will be a wider scope of awareness toward individual and contextual aspects of therapeutic change processes, toward different levels of memory involved in these processes, and toward the relationship between basic needs, sensation and cognition in therapeutic work. Further, a dialogue between the two approaches will pave the way for addressing the connection between fundamental awareness work in gestalt therapy and the tendency within cognitive therapy toward incorporating mindfulness as a therapeutic tool. In the conclusion of the article, additional complementary points between the two approaches are outlined. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  1. The Gestalt principle of similarity benefits visual working memory.

    Science.gov (United States)

    Peterson, Dwight J; Berryhill, Marian E

    2013-12-01

    Visual working memory (VWM) is essential for many cognitive processes, yet it is notably limited in capacity. Visual perception processing is facilitated by Gestalt principles of grouping, such as connectedness, similarity, and proximity. This introduces the question, do these perceptual benefits extend to VWM? If so, can this be an approach to enhance VWM function by optimizing the processing of information? Previous findings have demonstrated that several Gestalt principles (connectedness, common region, and spatial proximity) do facilitate VWM performance in change detection tasks (Jiang, Olson, & Chun, 2000; Woodman, Vecera, & Luck, 2003; Xu, 2002, 2006; Xu & Chun, 2007). However, one prevalent Gestalt principle, similarity, has not been examined with regard to facilitating VWM. Here, we investigated whether grouping by similarity benefits VWM. Experiment 1 established the basic finding that VWM performance could benefit from grouping. Experiment 2 replicated and extended this finding by showing that similarity was only effective when the similar stimuli were proximal. In short, the VWM performance benefit derived from similarity was constrained by spatial proximity, such that similar items need to be near each other. Thus, the Gestalt principle of similarity benefits visual perception, but it can provide benefits to VWM as well.

  2. To What Extent Do Gestalt Grouping Principles Influence Tactile Perception?

    Science.gov (United States)

    Gallace, Alberto; Spence, Charles

    2011-01-01

    Since their formulation by the Gestalt movement more than a century ago, the principles of perceptual grouping have primarily been investigated in the visual modality and, to a lesser extent, in the auditory modality. The present review addresses the question of whether the same grouping principles also affect the perception of tactile stimuli.…

  3. Clinical gestalt and the prediction of massive transfusion after trauma.

    Science.gov (United States)

    Pommerening, Matthew J; Goodman, Michael D; Holcomb, John B; Wade, Charles E; Fox, Erin E; Del Junco, Deborah J; Brasel, Karen J; Bulger, Eileen M; Cohen, Mitch J; Alarcon, Louis H; Schreiber, Martin A; Myers, John G; Phelan, Herb A; Muskat, Peter; Rahbar, Mohammad; Cotton, Bryan A

    2015-05-01

    Early recognition and treatment of trauma patients requiring massive transfusion (MT) has been shown to reduce mortality. While many risk factors predicting MT have been demonstrated, there is no universally accepted method or algorithm to identify these patients. We hypothesised that even among experienced trauma surgeons, the clinical gestalt of identifying patients who will require MT is unreliable. Transfusion and mortality outcomes after trauma were observed at 10 U.S. Level-1 trauma centres in patients who survived ≥ 30 min after admission and received ≥ 1 unit of RBC within 6h of arrival. Subjects who received ≥ 10 units within 24h of admission were classified as MT patients. Trauma surgeons were asked the clinical gestalt question "Is the patient likely to be massively transfused?" 10 min after the patients arrival. The performance of clinical gestalt to predict MT was assessed using chi-square tests and ROC analysis to compare gestalt to previously described scoring systems. Of the 1245 patients enrolled, 966 met inclusion criteria and 221 (23%) patients received MT. 415 (43%) were predicted to have a MT and 551(57%) were predicted to not have MT. Patients predicted to have MT were younger, more often sustained penetrating trauma, had higher ISS scores, higher heart rates, and lower systolic blood pressures (all pGestalt sensitivity was 65.6% and specificity was 63.8%. PPV and NPV were 34.9% and 86.2% respectively. Data from this large multicenter trial demonstrates that predicting the need for MT continues to be a challenge. Because of the increased mortality associated with delayed therapy, a more reliable algorithm is needed to identify and treat these severely injured patients earlier. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. A Review of the Non-Motoric Visual Gestalt Test and a Comparison with the Bender Visual-Motor Gestalt Test.

    Science.gov (United States)

    Elovitz, Gerald P.

    1979-01-01

    Measures of visual perception, such as the Bender Visual-Motor Gestalt Test (BVMGT) usually require motoric responding, i.e., drawing of figures. An alternative test, the Non-Motoric Visual Gestalt Test (NVGT), is compared with the BVMGT and shown to be superior in measuring visual-perceptual abilities that can discriminate poor and average…

  5. Pain inhibits pain; human brainstem mechanisms.

    Science.gov (United States)

    Youssef, A M; Macefield, V G; Henderson, L A

    2016-01-01

    Conditioned pain modulation is a powerful analgesic mechanism, occurring when a painful stimulus is inhibited by a second painful stimulus delivered at a different body location. Reduced conditioned pain modulation capacity is associated with the development of some chronic pain conditions and the effectiveness of some analgesic medications. Human lesion studies show that the circuitry responsible for conditioned pain modulation lies within the caudal brainstem, although the precise nuclei in humans remain unknown. We employed brain imaging to determine brainstem sites responsible for conditioned pain modulation in 54 healthy individuals. In all subjects, 8 noxious heat stimuli (test stimuli) were applied to the right side of the mouth and brain activity measured using functional magnetic resonance imaging. This paradigm was then repeated. However, following the fourth noxious stimulus, a separate noxious stimulus, consisting of an intramuscular injection of hypertonic saline into the leg, was delivered (conditioning stimulus). During this test and conditioning stimulus period, 23 subjects displayed conditioned pain modulation analgesia whereas 31 subjects did not. An individual's analgesic ability was not influenced by gender, pain intensity levels of the test or conditioning stimuli or by psychological variables such as pain catastrophizing or fear of pain. Brain images were processed using SPM8 and the brainstem isolated using the SUIT toolbox. Significant increases in signal intensity were determined during each test stimulus and compared between subjects that did and did not display CPM analgesia (ppain modulation circuitry provides a framework for the future investigations into the neural mechanisms responsible for the maintenance of persistent pain conditions thought to involve altered analgesic circuitry.

  6. Catalytic Mechanism of Human Alpha-galactosidase

    Energy Technology Data Exchange (ETDEWEB)

    Guce, A.; Clark, N; Salgado, E; Ivanen, D; Kulinskaya, A; Brumer, H; Garman, S

    2010-01-01

    The enzyme {alpha}-galactosidase ({alpha}-GAL, also known as {alpha}-GAL A; E.C. 3.2.1.22) is responsible for the breakdown of {alpha}-galactosides in the lysosome. Defects in human {alpha}-GAL lead to the development of Fabry disease, a lysosomal storage disorder characterized by the buildup of {alpha}-galactosylated substrates in the tissues. {alpha}-GAL is an active target of clinical research: there are currently two treatment options for Fabry disease, recombinant enzyme replacement therapy (approved in the United States in 2003) and pharmacological chaperone therapy (currently in clinical trials). Previously, we have reported the structure of human {alpha}-GAL, which revealed the overall structure of the enzyme and established the locations of hundreds of mutations that lead to the development of Fabry disease. Here, we describe the catalytic mechanism of the enzyme derived from x-ray crystal structures of each of the four stages of the double displacement reaction mechanism. Use of a difluoro-{alpha}-galactopyranoside allowed trapping of a covalent intermediate. The ensemble of structures reveals distortion of the ligand into a {sup 1}S{sub 3} skew (or twist) boat conformation in the middle of the reaction cycle. The high resolution structures of each step in the catalytic cycle will allow for improved drug design efforts on {alpha}-GAL and other glycoside hydrolase family 27 enzymes by developing ligands that specifically target different states of the catalytic cycle. Additionally, the structures revealed a second ligand-binding site suitable for targeting by novel pharmacological chaperones.

  7. The Southern California Sensory Integration Tests (Ayres) and the Bender Gestalt: a correlative study.

    Science.gov (United States)

    Kimball, J G

    1977-01-01

    The Southern California Sensory Integration Tests (SCSIT) and the Bender Gestalt are two measures used to evaluate children with suspected perceptual-motor deficits. Since these tests are used primarily by two groups of professionals, occupational therapists and psychologists, it was thought that studying the correlations between these two tests might help psychologists to know which children needed to be referred to an occupational therapist for sensory integrative evaluation, and might help the occupational therapist to understand the psychologist's use of the Bender Gestalt. The use of the Bender by the occupational therapist as a screening device for sensory integrative dysfunction was also investigated. The SCSIT and Bender were given to 26 children with suspected sensory integrative dysfunction. Scores on the Bender were found to be predictive of grouped scores on the Form and Space Perception and Praxis-Tactile sections of the SCSIT, but not of the Postural and Bilateral Integration section. It was concluded that when the Bender is used as a screening device for sensory integrative dysfunction, some measure of postural mechanisms must be included. Correlations between the Bender and individual tests of the SCSIT were also studied.

  8. Harmonic context influences pitch class equivalence judgments through gestalt and congruency effects.

    Science.gov (United States)

    Slana, Anka; Repovš, Grega; Fitch, W Tecumseh; Gingras, Bruno

    2016-05-01

    The context in which a stimulus is presented shapes the way it is processed. This effect has been studied extensively in the field of visual perception. Our understanding of how context affects the processing of auditory stimuli is, however, rather limited. Western music is primarily built on melodies (succession of pitches) typically accompanied by chords (harmonic context), which provides a natural template for the study of context effects in auditory processing. Here, we investigated whether pitch class equivalence judgments of tones are affected by the harmonic context within which the target tones are embedded. Nineteen musicians and 19 non-musicians completed a change detection task in which they were asked to determine whether two successively presented target tones, heard either in isolation or with a chordal accompaniment (same or different chords), belonged to the same pitch class. Both musicians and non-musicians were most accurate when the chords remained the same, less so in the absence of chordal accompaniment, and least when the chords differed between both target tones. Further analysis investigating possible mechanisms underpinning these effects of harmonic context on task performance revealed that both a change in gestalt (change in either chord or pitch class), as well as incongruency between change in target tone pitch class and change in chords, led to reduced accuracy and longer reaction times. Our results demonstrate that, similarly to visual processing, auditory processing is influenced by gestalt and congruency effects. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. A century of Gestalt psychology in visual perception: I. Perceptual grouping and figure-ground organization

    OpenAIRE

    Wagemans, Johan; Elder, James H.; Kubovy, Michael; Palmer, Stephen E.; Peterson, Mary A.; Singh, Manish; von der Heydt, Rüdiger

    2012-01-01

    In 1912, Max Wertheimer published his paper on phi motion, widely recognized as the start of Gestalt psychology. Because of its continued relevance in modern psychology, this centennial anniversary is an excellent opportunity to take stock of what Gestalt psychology has offered and how it has changed since its inception. We first introduce the key findings and ideas in the Berlin school of Gestalt psychology, and then briefly sketch its development, rise, and fall. Next, we discuss its empiri...

  10. Human Cooperation and Its Underlying Mechanisms.

    Science.gov (United States)

    Strang, Sabrina; Park, Soyoung Q

    2017-01-01

    Cooperation is a uniquely human behavior and can be observed across cultures. In order to maintain cooperative behavior in society, people are willing to punish deviant behavior on their own expenses and even without any personal benefits. Cooperation has been object of research in several disciplines. Psychologists, economists, sociologists, biologists, and anthropologists have suggested several motives possibly underlying cooperative behavior. In recent years, there has been substantial progress in understanding neural mechanisms enforcing cooperation. Psychological as well as economic theories were tested for their plausibility using neuroscientific methods. For example, paradigms from behavioral economics were adapted to be tested in the magnetic resonance imaging (MRI) scanner. Also, related brain functions were modulated by using transmagnetic brain stimulation (TMS). While cooperative behavior has often been associated with positive emotions, noncooperative behavior was found to be linked to negative emotions. On a neural level, the temporoparietal junction (TPJ), the striatum, and other reward-related brain areas have been shown to be activated by cooperation, whereas noncooperation has mainly been associated with activity in the insula.

  11. Unresolved questions in human copper pump mechanisms.

    Science.gov (United States)

    Wittung-Stafshede, Pernilla

    2015-11-01

    Copper (Cu) is an essential transition metal providing activity to key enzymes in the human body. To regulate the levels and avoid toxicity, cells have developed elaborate systems for loading these enzymes with Cu. Most Cu-dependent enzymes obtain the metal from the membrane-bound Cu pumps ATP7A/B in the Golgi network. ATP7A/B receives Cu from the cytoplasmic Cu chaperone Atox1 that acts as the cytoplasmic shuttle between the cell membrane Cu importer, Ctr1 and ATP7A/B. Biological, genetic and structural efforts have provided a tremendous amount of information for how the proteins in this pathway work. Nonetheless, basic mechanistic-biophysical questions (such as how and where ATP7A/B receives Cu, how ATP7A/B conformational changes and domain-domain interactions facilitate Cu movement through the membrane, and, finally, how target polypeptides are loaded with Cu in the Golgi) remain elusive. In this perspective, unresolved inquiries regarding ATP7A/B mechanism will be highlighted. The answers are important from a fundamental view, since mechanistic aspects may be common to other metal transport systems, and for medical purposes, since many diseases appear related to Cu transport dysregulation.

  12. PRACTICE OF GESTALT THEORY IN INDUSTRIAL PRODUCT DESIGN

    Directory of Open Access Journals (Sweden)

    Erkut ERYAYAR

    2011-08-01

    Full Text Available It is common knowledge that Gestalt Theory argues that an organized whole represents more than the sum of its parts. According to this theory, which emerged in studies on visual perception, a whole is made up of many parts each of which cannot reflect the whole on its own. Likewise, an industrial design comprises various parts which create a meaningful and functional whole. The success of a design can be measured against its ability to be perceived the same way as it is designed. In this respect, the inclusion of Gestalt theory principles in the process of design will enable the end product to differ from others and its user to perceive it in the right direction.

  13. [A scientific-cultural approach to the Gestalt concept].

    Science.gov (United States)

    Huneeus, F

    1976-06-01

    In the descriptions of the gestalt process formulated by F. S. Perls (Gestalt Therapy Verbatim, Real People Press, Lafayette, 1969) and other gestalt psychologists, it appears as if the gestalt formation was a general and universal tendency of living and non living matter as well. Broadly speaking, they state that a gestalt is something that in itself wants to be formed and completed, something which emerges as a distinct entity (figure) from a undifferentiated environment (background). From experience we know that perceptions of any kind, have this as a prerequisite: the perceived object or process has to out of equilibrium with the environment, otherwise it remains undetectable. On the other hand, the second law of thermodynamics prescribes that the tendency for spontaneous isolated processes is exactly the opposite. With time, processes tend towards equilibrium, things tend to equalize, heterogeneity tends to become homogeneity, order into disorder. Thus these two very important "rules of the game" for natural processes are seemingly contradictory. While one states that matter tends to differentiate into figure and ground, the other states that exactly the opposite is what will occur - with time, all distinction and differentiation will disappear. Of the many problems posed by biological entities to the physical sciences, their obvious differentiation within the growth span of the organism, is a flagrant violation of the second law and hence they, as a whole, escape the realm of thermodynamics. Only living organisms can go against the second law. Living organisms tend to form gestalts and they perceive the world through the formation of gestalt pairs. However, the first man-made creature that knowingly could obviate the results prescribed by the second law, was Maxwell's Demon. He can produce heterogeneity from homogeneity since he can handle information. In Maxwell's hypothetical experiment, his Demon can pick out fast molecules from slow molecules taking a

  14. Bender-Gestalt Test correlates of prognosis in Unipolar Depression

    Directory of Open Access Journals (Sweden)

    Mr. Anand Prakash MPhil

    2010-07-01

    Full Text Available The Bender-Gestalt test (B-G test was administered to examine its prognostic implications in an Ethiopian sample with unipolar depression. Total 30 patients with moderate level of depression were included in study and their time taken was compared against the performance on the B-G test. Finally, a significant difference was found between time taken and Z-scores of the test supporting the prognostic value of this test in unipolar depression.

  15. Gestalt-like representations hijack Chunk-and-Pass processing.

    Science.gov (United States)

    Dumitru, Magda L

    2016-01-01

    Christiansen & Chater (C&C) make two related and somewhat contradictory claims, namely that the ever abstract language representations built during Chunk-and-Pass processing allow for ever greater interference from extra-linguistic information, and that it is nevertheless the language system that re-codes incoming information into abstract representations. I analyse these claims and discuss evidence suggesting that Gestalt-like representations hijack Chunk-and-Pass processing.

  16. To what extent do Gestalt grouping principles influence tactile perception?

    Science.gov (United States)

    Gallace, Alberto; Spence, Charles

    2011-07-01

    Since their formulation by the Gestalt movement more than a century ago, the principles of perceptual grouping have primarily been investigated in the visual modality and, to a lesser extent, in the auditory modality. The present review addresses the question of whether the same grouping principles also affect the perception of tactile stimuli. Although, to date, only a few studies have explicitly investigated the existence of Gestalt grouping principles in the tactile modality, we argue that many more studies have indirectly provided evidence relevant to this topic. Reviewing this body of research, we argue that similar principles to those reported previously in visual and auditory studies also govern the perceptual grouping of tactile stimuli. In particular, we highlight evidence showing that the principles of proximity, similarity, common fate, good continuation, and closure affect tactile perception in both unimodal and crossmodal settings. We also highlight that the grouping of tactile stimuli is often affected by visual and auditory information that happen to be presented simultaneously. Finally, we discuss the theoretical and applied benefits that might pertain to the further study of Gestalt principles operating in both unisensory and multisensory tactile perception.

  17. Oscillatory dynamics of Gestalt perception in schizophrenia revisited.

    Science.gov (United States)

    Spencer, Kevin M; Ghorashi, Shahab

    2014-01-01

    Abnormalities in γ oscillations (30-100 Hz) in the scalp-recorded electroencephalogram (EEG) have been proposed to reflect neural circuitry abnormalities in schizophrenia. Oscillations in the γ band are thought to play an important role in visual perception, mediating the binding of visual features into coherent objects. However, there is relatively little evidence to date of deficits in γ-mediated processes associated with Gestalt perception in schizophrenia. Fourteen healthy control subjects (HC) and 17 chronic schizophrenia patients (SZ) discriminated between illusory Kanisza Squares and No-Square control stimuli, indicating their judgment with a manual button press. Time-frequency decomposition of the EEG was computed with the Morlet wavelet transform. Time-frequency maps of phase locking factor (PLF) values were calculated for stimulus- and response-locked oscillations. HC and SZ did not differ in reaction time, error rate, an early ERP effect associated with Gestalt processing, nor an early visual-evoked γ oscillation. Two response-locked high γ effects had greater PLF for Square than No-Square stimuli in HC, and the reverse pattern in SZ. One of these effects was correlated with thought disorder symptom ratings in SZ. SZ demonstrated abnormalities in γ oscillations associated with the perception of Gestalt objects, while their early visual-evoked γ activity was mostly normal, contrary to previous results. This study supports the hypothesis that high-frequency oscillations are sensitive to aspects of psychosis.

  18. Oscillatory Dynamics of Gestalt Perception in Schizophrenia Revisited

    Directory of Open Access Journals (Sweden)

    Kevin M Spencer

    2014-02-01

    Full Text Available Background: Abnormalities in γ oscillations (30-100 Hz in the scalp-recorded electroencephalogram (EEG have been proposed to reflect neural circuitry abnormalities in schizophrenia. Oscillations in the γ band are thought to play an important role in visual perception, mediating the binding of visual features into coherent objects. However, there is relatively little evidence to date of deficits in γ-mediated processes associated with Gestalt perception in schizophrenia.Methods: Fourteen healthy control subjects (HC and 17 chronic schizophrenia patients (SZ discriminated between illusory Kanisza Squares and No-Square control stimuli, indicating their judgment with a manual button press. Time-frequency decomposition of the EEG was computed with the Morlet wavelet transform. Time-frequency maps of phase locking factor (PLF values were calculated for stimulus- and response-locked oscillations.Results: HC and SZ did not differ in reaction time, error rate, an early ERP effect associated with Gestalt processing, nor an early visual-evoked γ oscillation. Two response-locked high γ effects had greater PLF for Square than No-Square stimuli in HC, and the reverse pattern in SZ. One of these effects was correlated with thought disorder symptom ratings in SZ.Conclusions: SZ demonstrated abnormalities in γ oscillations associated with the perception of Gestalt objects, while their early visual-evoked γ activity was mostly normal, contrary to previous results. This study supports the hypothesis that high-frequency oscillations are sensitive to aspects of psychosis.

  19. Human vagal baroreflex mechanisms in space.

    Science.gov (United States)

    Eckberg, Dwain L; Halliwill, John R; Beightol, Larry A; Brown, Troy E; Taylor, J Andrew; Goble, Ross

    2010-04-01

    Although astronauts' cardiovascular function is normal while they are in space, many have altered haemodynamic responses to standing after they return to Earth, including inordinate tachycardia, orthostatic hypotension, and uncommonly, syncope. Simulated microgravity impairs vagal baroreceptor-cardiac reflex function and causes orthostatic hypotension. Actual microgravity, however, has been shown to either increase, or not change vagal baroreflex gain. In this study, we tested the null hypothesis that spaceflight does not impair human baroreflex mechanisms. We studied 11 American and two German astronauts before, during (flight days 2-8), and after two, 9- and 10-day space shuttle missions, with graded neck pressure and suction, to elicit sigmoid, vagally mediated carotid baroreflex R-R interval responses. Baseline systolic pressures tended to be higher in space than on Earth (P = 0.015, repeated measures analysis of variance), and baseline R-R intervals tended to be lower (P = 0.049). Baroreceptor-cardiac reflex relations were displaced downward on the R-R interval axis in space. The average range of R-R interval responses to neck pressure changes declined from preflight levels by 37% on flight day 8 (P = 0.051), maximum R-R intervals declined by 14% (P = 0.003), and vagal baroreflex gain by 9% (P = 0.009). These measures returned to preflight levels by 7-10 days after astronauts returned to Earth. This study documents significant increases of arterial pressure and impairment of vagal baroreflex function in space. These results and results published earlier indicate that microgravity exposure augments sympathetic, and diminishes vagal cardiovascular influences.

  20. Microstructure and mechanics of human resistance arteries.

    Science.gov (United States)

    Bell, J S; Adio, A O; Pitt, A; Hayman, L; Thorn, C E; Shore, A C; Whatmore, J L; Winlove, C P

    2016-12-01

    Vascular diseases such as diabetes and hypertension cause changes to the vasculature that can lead to vessel stiffening and the loss of vasoactivity. The microstructural bases of these changes are not presently fully understood. We present a new methodology for stain-free visualization, at a microscopic scale, of the morphology of the main passive components of the walls of unfixed resistance arteries and their response to changes in transmural pressure. Human resistance arteries were dissected from subcutaneous fat biopsies, mounted on a perfusion myograph, and imaged at varying transmural pressures using a multimodal nonlinear microscope. High-resolution three-dimensional images of elastic fibers, collagen, and cell nuclei were constructed. The honeycomb structure of the elastic fibers comprising the internal elastic layer became visible at a transmural pressure of 30 mmHg. The adventitia, comprising wavy collagen fibers punctuated by straight elastic fibers, thinned under pressure as the collagen network straightened and pulled taut. Quantitative measurements of fiber orientation were made as a function of pressure. A multilayer analytical model was used to calculate the stiffness and stress in each layer. The adventitia was calculated to be up to 10 times as stiff as the media and experienced up to 8 times the stress, depending on lumen diameter. This work reveals that pressure-induced reorganization of fibrous proteins gives rise to very high local strain fields and highlights the unique mechanical roles of both fibrous networks. It thereby provides a basis for understanding the micromechanical significance of structural changes that occur with age and disease.

  1. Recognition of Grouping Patterns in Trademarks Based on the Gestalt Psychology

    Science.gov (United States)

    Iguchi, Hiromasa; Abe, Koji; Misawa, Tadanobu; Kimura, Haruhiko; Daido, Yoshimasa

    According to the Gestalt principals, in this paper, we model features for measuring the attraction degree between couples of image components, and grouping areas in trademark images are recognized. This investigation would be used for content-based image retrieval from the view of mirroring human perception for images. The features of proximity, shape similarity, closure, and good continuation are extracted from every combination of two components in an image. After that, according to results of the judgments, a grouping pattern for the query is fixed. Besides, changing combination of the features, the proposed method can output plural grouping patterns. In the experiments, we have evaluated the proposed method on 74 test images comparing between outputs by the proposed method and grouping patterns for the test images obtained from results of questionnaires by 104 participants.

  2. Lung No dules Detection in CT Images Using Gestalt-Based Algorithm

    Institute of Scientific and Technical Information of China (English)

    QIU Shi; WEN Desheng; CUI Ying; FENG Jun

    2016-01-01

    To overcome low accuracy and high false positive of existing computer-aided lung nodules detec-tion. We propose a novel lung nodule detection scheme based on the Gestalt visual cognition theory. The pro-posed scheme involves two parts which simulate human eyes cognition features such as simplicity, integrity and classification. Firstly, lung region was segmented from lung Computed tomography (CT) sequences. Then local three-dimensional information was integrated into the Maximum intensity projection (MIP) images from axial, coronal and sagittal profiles. In this way, lung nodules and vascular are strengthened and discriminated based on pathologic image characteristics of lung nodules. The experimental database includes fifty-three high resolution CT images contained lung nodules, which had been confirmed by biopsy. The experimental results show that, the accuracy rate of the proposed algorithm achieves 91.29%. The proposed frame-work improves performance and computation speed for computer aided nodules detection.

  3. Gestalt Practice and Arts-Based Training for Leadership, Innovation and Change Management Skills

    Science.gov (United States)

    Liotas, Naoum

    2014-01-01

    Gestalt practice and arts-based training has been examined and evaluated using evidence from the literature and personal experience. Gestalt practice allows the training and learning process to take into account the intrapersonal as well as the interpersonal aspects of the group and the individuals involved: the resulting knowledge and…

  4. Predicting Reading and Arithmetic Achievement by Using Bender Gestalt and Visual Memory Technique.

    Science.gov (United States)

    Rust, James O.; And Others

    1982-01-01

    First grade students were administered a screening battery that included the Otis-Lennon Mental Ability Test, the Metropolitan Readiness Test, the Bender Gestalt Test, and the Visual Memory Technique. Stepwise regression equations revealed that the Bender Gestalt Test significantly increased the predictive power of the test battery. (FL)

  5. Perls with Gloria Re-reviewed: Gestalt Techniques and Perls's Practices.

    Science.gov (United States)

    Dolliver, Robert H.

    1991-01-01

    Reviews the filmed interview with Gloria by Perls (1965) which demonstrated some standard Gestalt therapy techniques and presents examples from film. Identifies discrepancies between Perls's description of Gestalt therapeutic processes and his interview behavior. Makes reflections on the inherent difficulties with the concept of the emerging…

  6. Reviewing the Past in the Here and Now: Using Gestalt Therapy Techniques with Life Review.

    Science.gov (United States)

    Crose, Royda

    1990-01-01

    Discusses a Gestalt therapy perspective on the life review process and the use of Gestalt therapy techniques in helping the older client achieve resolution of past conflicts. Notes that, with such resolution, the developmental task of ego integration in the final years of life may be realized. (Author/NB)

  7. Breaking Ground: A Study of Gestalt Therapy Theory and Holland's Theory of Vocational Choice.

    Science.gov (United States)

    Hartung, Paul J.

    In both Gestalt therapy and Holland's theory of vocational choice, person-environment interaction receives considerable emphasis. Gestalt therapy theory suggests that people make contact (that is, meet needs) through a characteristic style of interacting with the environment. Holland identifies six personality types in his theory and asserts that…

  8. The Influence of Integrative Gestalt Therapy on Acquisition of Daily Life Skills and Habits.

    Science.gov (United States)

    Zic, Anamarija; And Others

    This study evaluated the effects of Integrative Gestalt Therapy on the intellectual aspects of social competence in 13 children, ages 7 to 11, living in Zagreb, Croatia. These children had intellectual disabilities (IQ 54 to 84) as well as psychological and/or behavior problems. Integrative Gestalt Therapy emphasizes the wholeness of a person's…

  9. Good Moments in Gestalt Therapy: A Descriptive Analysis of Two Perls Sessions.

    Science.gov (United States)

    Boulet, Donald; And Others

    1993-01-01

    Analyzed two Gestalt therapy sessions conducted by Fritz Perls using category system for identifying in-session client behaviors valued by Gestalt therapists. Four judges independently rated 210 client statements. Found common pattern of therapeutic movement: initial phase dominated by building block good moments and second phase characterized by…

  10. Comparison of Native American Navajo Bender-Gestalt Performance with Koppitz and Sompa Norms.

    Science.gov (United States)

    Moore, Clay L.; Zarske, John A.

    1984-01-01

    Compared Bender-Gestalt performance of 452 Navajo children with 1974 Koppitz and System of Multicultural Pluralistic Assessment norms (SOMPA), and investigated the use of the Bender-Gestalt for diagnosing learning disabilities. Results suggested the Koppitz and SOMPA White norms may be useful in psychological assessment of Navajo children. (JAC)

  11. A Century of Gestalt Psychology in Visual Perception: II. Conceptual and Theoretical Foundations

    Science.gov (United States)

    Wagemans, Johan; Feldman, Jacob; Gepshtein, Sergei; Kimchi, Ruth; Pomerantz, James R.; van der Helm, Peter A.; van Leeuwen, Cees

    2012-01-01

    Our first review article (Wagemans et al., 2012) on the occasion of the centennial anniversary of Gestalt psychology focused on perceptual grouping and figure-ground organization. It concluded that further progress requires a reconsideration of the conceptual and theoretical foundations of the Gestalt approach, which is provided here. In…

  12. A Century of Gestalt Psychology in Visual Perception: I. Perceptual Grouping and Figure-Ground Organization

    Science.gov (United States)

    Wagemans, Johan; Elder, James H.; Kubovy, Michael; Palmer, Stephen E.; Peterson, Mary A.; Singh, Manish; von der Heydt, Rudiger

    2012-01-01

    In 1912, Max Wertheimer published his paper on phi motion, widely recognized as the start of Gestalt psychology. Because of its continued relevance in modern psychology, this centennial anniversary is an excellent opportunity to take stock of what Gestalt psychology has offered and how it has changed since its inception. We first introduce the key…

  13. Gestalt Perception and Local-Global Processing in High-Functioning Autism

    Science.gov (United States)

    Bolte, Sven; Holtmann, Martin; Poustka, Fritz; Scheurich, Armin; Schmidt, Lutz

    2007-01-01

    This study examined gestalt perception in high-functioning autism (HFA) and its relation to tasks indicative of local visual processing. Data on of gestalt perception, visual illusions (VI), hierarchical letters (HL), Block Design (BD) and the Embedded Figures Test (EFT) were collected in adult males with HFA, schizophrenia, depression and…

  14. Gestalt Practice and Arts-Based Training for Leadership, Innovation and Change Management Skills

    Science.gov (United States)

    Liotas, Naoum

    2014-01-01

    Gestalt practice and arts-based training has been examined and evaluated using evidence from the literature and personal experience. Gestalt practice allows the training and learning process to take into account the intrapersonal as well as the interpersonal aspects of the group and the individuals involved: the resulting knowledge and…

  15. Gestalt Perceptual Organization of Visual Stimuli Captures Attention Automatically: Electrophysiological Evidence.

    Science.gov (United States)

    Marini, Francesco; Marzi, Carlo A

    2016-01-01

    The visual system leverages organizational regularities of perceptual elements to create meaningful representations of the world. One clear example of such function, which has been formalized in the Gestalt psychology principles, is the perceptual grouping of simple visual elements (e.g., lines and arcs) into unitary objects (e.g., forms and shapes). The present study sought to characterize automatic attentional capture and related cognitive processing of Gestalt-like visual stimuli at the psychophysiological level by using event-related potentials (ERPs). We measured ERPs during a simple visual reaction time task with bilateral presentations of physically matched elements with or without a Gestalt organization. Results showed that Gestalt (vs. non-Gestalt) stimuli are characterized by a larger N2pc together with enhanced ERP amplitudes of non-lateralized components (N1, N2, P3) starting around 150 ms post-stimulus onset. Thus, we conclude that Gestalt stimuli capture attention automatically and entail characteristic psychophysiological signatures at both early and late processing stages. Highlights We studied the neural signatures of the automatic processes of visual attention elicited by Gestalt stimuli. We found that a reliable early correlate of attentional capture turned out to be the N2pc component. Perceptual and cognitive processing of Gestalt stimuli is associated with larger N1, N2, and P3.

  16. A Century of Gestalt Psychology in Visual Perception: I. Perceptual Grouping and Figure-Ground Organization

    Science.gov (United States)

    Wagemans, Johan; Elder, James H.; Kubovy, Michael; Palmer, Stephen E.; Peterson, Mary A.; Singh, Manish; von der Heydt, Rudiger

    2012-01-01

    In 1912, Max Wertheimer published his paper on phi motion, widely recognized as the start of Gestalt psychology. Because of its continued relevance in modern psychology, this centennial anniversary is an excellent opportunity to take stock of what Gestalt psychology has offered and how it has changed since its inception. We first introduce the key…

  17. A Century of Gestalt Psychology in Visual Perception: II. Conceptual and Theoretical Foundations

    Science.gov (United States)

    Wagemans, Johan; Feldman, Jacob; Gepshtein, Sergei; Kimchi, Ruth; Pomerantz, James R.; van der Helm, Peter A.; van Leeuwen, Cees

    2012-01-01

    Our first review article (Wagemans et al., 2012) on the occasion of the centennial anniversary of Gestalt psychology focused on perceptual grouping and figure-ground organization. It concluded that further progress requires a reconsideration of the conceptual and theoretical foundations of the Gestalt approach, which is provided here. In…

  18. Gestalt Perception and Local-Global Processing in High-Functioning Autism

    Science.gov (United States)

    Bolte, Sven; Holtmann, Martin; Poustka, Fritz; Scheurich, Armin; Schmidt, Lutz

    2007-01-01

    This study examined gestalt perception in high-functioning autism (HFA) and its relation to tasks indicative of local visual processing. Data on of gestalt perception, visual illusions (VI), hierarchical letters (HL), Block Design (BD) and the Embedded Figures Test (EFT) were collected in adult males with HFA, schizophrenia, depression and…

  19. International Human Rights Mechanism and Construction of Harmonious Human Rights Relations

    Institute of Scientific and Technical Information of China (English)

    LIU JIE

    2007-01-01

    @@ The international human rights mechanism is a product of the pursuit for peace and justice of the human society. As the core values of the international human rights mechanism, the universal human rights standards provide the international community with a basic path of human rights development in different countries. In recent years a limited few of countries have utilized the universal human rights standards to promote their own strategic wills, and interfere in the sovereignty and domestic affairs of other countries with the excuse of human rights.However, the establishment and improvement of the human rights mechanism provide an institutional mode and path for the promotion of equality, dialog, and cooperation in the human rights issues of all countries. In addition, the establishment and improvement of the human rights mechanism also benefit the construction of harmonious human rights relations in a faster pace on the precondition of respect for national sovereignty by the international community.

  20. [Significance of the gestalt, primary, and family therapy for psychoanalysis].

    Science.gov (United States)

    Sperling, E

    1978-01-01

    The technical therapeutic premises and the application of gestalt-, primal- and familytherapy are investigated. It is concluded, that these premises and application attempt to do justice to the change of the patients and to the widely varied offer of serious syndromes rather than to psychoanalytic routine by "Uberinvestierung" in the patient. Not only the insistence on ego-psychology but also the emphasis on transference as the only therapeutic medium are viewed critically. The confrontation is in competition with the interpretion; The acting out can help to intensify experience. As the most important result for psychoanalytic work appears the conclusion "ex omissione".

  1. The validity of the Bender-Gestalt emotional indicators.

    Science.gov (United States)

    Rossini, E D; Kaspar, J C

    1987-01-01

    We evaluated the concurrent validity of the revised Bender-Gestalt emotional indicators (Koppitz, 1975) among three groups of children in the 7- to 10-year age range: adjustment disorder, behavior disorder, and normal control. The concurrent validity of the emotional indicators total score was demonstrated. Notably, with the developmental level controlled, both clinical groups produced significantly more emotional indicators than the control group, although the two clinical groups could not be differentiated. Nominal-data analyses of the 13 individual emotional indicators indicated that three specific indicators (confused order, large size, boxed figures) possessed validity as pathognomonic signs. We discuss issues concerning the use of the emotional indicators in clinical practice.

  2. Bender-Gestalt reproduction times for retarded adults.

    Science.gov (United States)

    Andert, J N; Hustak, T L; Dinning, W D

    1978-10-01

    Examined the length of time required by retarded adults to complete the Bender-Gestalt test with a sample of 241 test administrations. In order to provide for normative comparisons among retarded adults, descriptive data are presented on the Bender reproduction times of adults in three AAMD ranges of retardation based on WAIS IQs and two ranges based on Stanford-Binet IQs. Negative correlations were found between the length of Bender times and the degree of retardation. The duration of Bender times was correlated positively with the number of errors in reproduction as measured by the Koppitz developmental scoring system.

  3. Revisiting Wittgenstein on Köhler and Gestalt psychology.

    Science.gov (United States)

    Benjafield, John G

    2008-01-01

    In an article in this journal, Nicholas Pastore rejected Ludwig Wittgenstein's critique of Wolfgang Köhler and Gestalt psychology. Pastore appears not to have appreciated Wittgenstein's argument that Köhler mistook conceptual questions for factual ones. A simi-lar confusion seems to underlie at least some aspects of contemporary neuroscience. Be that as it may, Wittgenstein has had minimal influence on the research practices of psychologists while Köhler remains influential. This outcome would not have surprised Wittgenstein, who predicted that scientists would not see his work as relevant to theirs.

  4. La psicologia della Gestalt come scuola di rispetto

    Directory of Open Access Journals (Sweden)

    Giuseppe Galli

    2012-01-01

    Full Text Available Gestalt Psychology as a School of Respect - Respect as “phenomenological principle” means that one must respect phenomenal reality in the same way as physical reality. Respect as “epistemological principle” means that studying the self of the other the researcher must establish an intimate and equal relation with this person. This is not an accidental aspect, but one of the basic epistemological factors of the “field” in the sense of Lewin’s “action-research”. Respect as “educational principle” means that in the caring for a living being we must respect its inner factors and conditions and its rhythm of development.

  5. Mechanical Properties of Four Human Longbones.

    Science.gov (United States)

    1981-11-30

    Ultimate Properties of Compact Bone Tissue," J. Biomechanics, 1975, pp. 393-405. 41. Bass, William M., Human Osteology: A Laboratory and Field Manual of...bone’s proximal and distal epiphyses. Most of the measurements used can be found in the antropological literature [1, 2, 4, 5, 61. Those that cannot...using strain sensing load cells connected to j a manual switch and balance unit and digital display. The torque applied was inferred by the tensile

  6. Gestalt descriptions embodiments and medical image interpretation

    DEFF Research Database (Denmark)

    Friis, Jan Kyrre Berg Olsen

    2017-01-01

    In this paper I will argue that medical specialists interpret and diagnose through technological mediations like X-ray and fMRI images, and by actualizing embodied skills tacitly they are determining the identity of objects in the perceptual field. The initial phase of human interpretation of vis...

  7. institutional mechanisms for human rights protection in nigeria

    African Journals Online (AJOL)

    Mofasony

    legal and institutional mechanisms for protecting the human rights guaranteed in .... by the Constitution of the Federal Republic of Nigeria, African Charter, the .... special care administrative acts which are or appear to be contrary to any law or.

  8. Epigenetic Mechanisms of the Aging Human Retina

    Science.gov (United States)

    Pennington, Katie L.; DeAngelis, Margaret M.

    2015-01-01

    Degenerative retinal diseases, such as glaucoma, age-related macular degeneration, and diabetic retinopathy, have complex etiologies with environmental, genetic, and epigenetic contributions to disease pathology. Much effort has gone into elucidating both the genetic and the environmental risk factors for these retinal diseases. However, little is known about how these genetic and environmental risk factors bring about molecular changes that lead to pathology. Epigenetic mechanisms have received extensive attention of late for their promise of bridging the gap between environmental exposures and disease development via their influence on gene expression. Recent studies have identified epigenetic changes that associate with the incidence and/or progression of each of these retinal diseases. Therefore, these epigenetic modifications may be involved in the underlying pathological mechanisms leading to blindness. Further genome-wide epigenetic studies that incorporate well-characterized tissue samples, consider challenges similar to those relevant to gene expression studies, and combine the genome-wide epigenetic data with genome-wide genetic and expression data to identify additional potentially causative agents of disease are needed. Such studies will allow researchers to create much-needed therapeutics to prevent and/or intervene in disease progression. Improved therapeutics will greatly enhance the quality of life and reduce the burden of disease management for millions of patients living with these potentially blinding conditions. PMID:26966390

  9. Mechanics of human voice production and control

    Science.gov (United States)

    Zhang, Zhaoyan

    2016-01-01

    As the primary means of communication, voice plays an important role in daily life. Voice also conveys personal information such as social status, personal traits, and the emotional state of the speaker. Mechanically, voice production involves complex fluid-structure interaction within the glottis and its control by laryngeal muscle activation. An important goal of voice research is to establish a causal theory linking voice physiology and biomechanics to how speakers use and control voice to communicate meaning and personal information. Establishing such a causal theory has important implications for clinical voice management, voice training, and many speech technology applications. This paper provides a review of voice physiology and biomechanics, the physics of vocal fold vibration and sound production, and laryngeal muscular control of the fundamental frequency of voice, vocal intensity, and voice quality. Current efforts to develop mechanical and computational models of voice production are also critically reviewed. Finally, issues and future challenges in developing a causal theory of voice production and perception are discussed. PMID:27794319

  10. Mechanisms of trinucleotide repeat instability during human development.

    Science.gov (United States)

    McMurray, Cynthia T

    2010-11-01

    Trinucleotide expansion underlies several human diseases. Expansion occurs during multiple stages of human development in different cell types, and is sensitive to the gender of the parent who transmits the repeats. Repair and replication models for expansions have been described, but we do not know whether the pathway involved is the same under all conditions and for all repeat tract lengths, which differ among diseases. Currently, researchers rely on bacteria, yeast and mice to study expansion, but these models differ substantially from humans. We need now to connect the dots among human genetics, pathway biochemistry and the appropriate model systems to understand the mechanism of expansion as it occurs in human disease.

  11. Effectiveness of hypnosis therapy and Gestalt therapy as depression treatments

    Directory of Open Access Journals (Sweden)

    Elizabeth González-Ramírez

    2017-03-01

    Full Text Available We analyzed the effectiveness of two psychological therapies to treat depression in the Culiacan population, Mexico. According to criteria of MINI (international Neuropsychiatric interview, 30 individuals from a total of 300 were selected and diagnosed with some kind of depression. Patients were divided in three groups: 1 treatment with hypnosis therapy, 2 treatment with Gestalt-hypnosis therapy, and 3 control group. Before and after the treatments the Beck Anxiety Inventory (BAI was applied to know the depression level of the analyzed groups. The results show that the three groups were presenting a moderated level of depression. The groups under hypnosis therapy and Gestalt-hypnosis therapy show statistical differences between pre-test and post-test. The hypnosis therapy shows significant statistic differences to treat depression with respect to the other two groups. In conclusion, the therapeutic hypnosis is an effective treatment and has relevance to treat depression, while other therapeutic treatments tend to be slow and with minor result. This study is the first of this kind carried out in Culiacan in Sinaloa, Mexico.

  12. Structure and mechanical behavior of human hair.

    Science.gov (United States)

    Yu, Yang; Yang, Wen; Wang, Bin; Meyers, Marc André

    2017-04-01

    The understanding of the mechanical behavior of hair under various conditions broadens our knowledge in biological materials science and contributes to the cosmetic industry. The hierarchical organization of hair is studied from the intermediate filament to the structural levels. The effects of strain rate, relative humidity, and temperature are evaluated. Hair exhibits a high tensile strength, 150-270MPa, which is significantly dependent on strain rate and humidity. The strain-rate sensitivity, approximately 0.06-0.1, is comparable to that of other keratinous materials and common synthetic polymers. The structures of the internal cortex and surface cuticle are affected by the large tensile extension. One distinguishing feature, the unwinding of the α-helix and the possible transformation to β-sheet structure of keratin under tension, which affects the ductility of hair, is analytically evaluated and incorporated into a constitutive equation. A good agreement with the experimental results is obtained. This model elucidates the tensile response of the α-keratin fibers. The contributions of elastic and plastic strains on reloading are evaluated and correlated to structural changes. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Parametric studies of human thermal mechanisms and measurements.

    Science.gov (United States)

    Thornton, S B; Nair, S S

    2000-04-01

    A systematic methodology is proposed for mathematically quantifying the effects of measurement inaccuracies due to instrument uncertainty in a human calorimetry project. Human thermal mechanisms are poorly understood at the systems level and this study investigates the importance of these mechanisms quantitatively. The proposed methodology uses sensitivity derivatives combined with sensor accuracies to quantify the effect of each heat transfer mechanism contributing to the errors in the system equations. The method is applicable to any differentiable model to be validated by experimentation. To illustrate the methodology, two example cases, a reclining nude resting subject and a reclining clothed working subject, are analyzed. The calculated expected errors clearly suggest specific modifications.

  14. The application of Gestalt principles in a middle school science classroom

    Science.gov (United States)

    Akbar, Salma

    This thesis is an initial step in creating an educational philosophy for a private, affiliated school through the application of Gestalt principles. Middle school science students were given a pre-test for measuring their critical thinking skills which were defined by Gestalt principles (Blosser 1973) and modeled on real life science fair project scenarios. After taking the pre-test, the students were assigned science fair projects. Simultaneously they were informally assessed by a rubric. Finally, the students took a post-test to see if their critical thinking skills improved as a result of being guided to think along the lines of the Gestalt learning theory. As a result of completing the procedure, the researcher found that the students' critical thinking skills were improved as evidenced by the higher test scores on the post-test. The pilot study was successful and Gestalt Principles could be successfully implemented as part of the private school curriculum.

  15. Differential Effect of Amphetamine Optical Isomers on Bender Gestalt Performance of the Minimally Brain Dysfunctioned

    Science.gov (United States)

    Arnold, L. Eugene; And Others

    1978-01-01

    The differential effect of amphetamine optical isomers on Bender Gestalt performance was examined in 31 hyperkinetic minimally brain dysfunctioned children between the ages of 4 and 12 years, using a double-blind Latin-square crossover comparison. (Author)

  16. An Item Analysis and Validity Investigation of Bender Visual Motor Gestalt Test Score Items

    Science.gov (United States)

    Lambert, Nadine M.

    1971-01-01

    This investigation attempted to demonstrate the utility of standard item analysis procedures for selecting the most reliable and valid items for scoring Bender Visual Motor Gestalt Test test records. (Author)

  17. Comparison of Bender-Gestalt and WISC Correlations for Puerto Rican, White and Negro Children

    Science.gov (United States)

    Marmorale, Ann M.; Brown, Fred

    1975-01-01

    This study investigated whether a positive relationship between Bender-Gestalt performance and intelligence test scores would be found for Puerto Rican children and, as well, the generalizability of previous results obtained with Negro children. (Author/RK)

  18. Bender Gestalt Signs and Anti-Social Acting Out Tendencies in Adolescents

    Science.gov (United States)

    Brannigan, Gary G.; Benowity, Martin L.

    1975-01-01

    This study explores the relationship between performance on the Bender-Gestalt test and antisocial acting out tendencies in adolescents. Results indicate that uneven figure size and exaggerated curvature are the best indicators of antisocial acting out tendencies. (Author)

  19. Values in Fritz Perls's Gestalt Therapy: On the Dangers of Half-Truths.

    Science.gov (United States)

    Cadwallader, Eva H.

    1984-01-01

    Examines some of the values in Perls's theory of psychotherapy, which his Gestalt Prayer epitomizes. Argues that at least five of the major value claims presupposed by his psychotherapeutic theory and practice are in fact dangerous half-truths. (JAC)

  20. A Comparison of Gestalt and Relationship Enhancement Treatments with Married Couples.

    Science.gov (United States)

    Jessee, Randall E.; Guerney, Bernard G., Jr.

    1981-01-01

    Compared the effectiveness of Relationship Enhancement and Gestalt Relationship Facilitation. Results indicated couples (N=36) in both groups made significant gains, but Relationship Enhancement participants achieved greater gains in communication, relationship satisfaction, and ability to handle problems. (Author/JAC)

  1. The Bender-Gestalt Test in Differential Diagnosis of Adolescents with Learning Difficulties

    Science.gov (United States)

    Mordock, John B.; and others

    1968-01-01

    Attempt to assess efficiency of Haine and Koppitz scoring systems with Bender-Gestalt in ability to differentiate between brain-damaged and other young people in a residential treatment center did not prove useful. (Author/CJ)

  2. Values in Fritz Perls's Gestalt Therapy: On the Dangers of Half-Truths.

    Science.gov (United States)

    Cadwallader, Eva H.

    1984-01-01

    Examines some of the values in Perls's theory of psychotherapy, which his Gestalt Prayer epitomizes. Argues that at least five of the major value claims presupposed by his psychotherapeutic theory and practice are in fact dangerous half-truths. (JAC)

  3. Subliminal Gestalt grouping: evidence of perceptual grouping by proximity and similarity in absence of conscious perception.

    Science.gov (United States)

    Montoro, Pedro R; Luna, Dolores; Ortells, Juan J

    2014-04-01

    Previous studies making use of indirect processing measures have shown that perceptual grouping can occur outside the focus of attention. However, no previous study has examined the possibility of subliminal processing of perceptual grouping. The present work steps forward in the study of perceptual organization, reporting direct evidence of subliminal processing of Gestalt patterns. In two masked priming experiments, Gestalt patterns grouped by proximity or similarity that induced either a horizontal or vertical global orientation of the stimuli were presented as masked primes and followed by visible targets that could be congruent or incongruent with the orientation of the primes. The results showed a reliable priming effect in the complete absence of prime awareness for both proximity and similarity grouping principles. These findings suggest that a phenomenal report of the Gestalt pattern is not mandatory to observe an effect on the response based on the global properties of Gestalt stimuli. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Gestalt therapy approaches with aggressive children in a day care setting

    OpenAIRE

    Maxey, Win

    1987-01-01

    This research study was designed to evaluate whether or not Gestalt therapy approaches could be used effectively when intervening with aggressive acts in a day care setting. Five focus children were observed at timed intervals as to whether or not they were aggressive, how the caretaker intervened, and how the children responded to the caretaker intervention. After a baseline of aggressive acts was established, caretakers were trained to use Gestalt therapy interventio...

  5. Gestalt perceptual organization of visual stimuli captures attention automatically: Electrophysiological evidence

    OpenAIRE

    Francesco Marini; Carlo Alberto Marzi

    2016-01-01

    The visual system leverages organizational regularities of perceptual elements to create meaningful representations of the world. One clear example of such function, which has been formalized in the Gestalt psychology principles, is the perceptual grouping of simple visual elements (e.g., lines and arcs) into unitary objects (e.g., forms and shapes). The present study sought to characterize automatic attentional capture and related cognitive processing of Gestalt-like visual stimuli at the ps...

  6. Gestalt Perceptual Organization of Visual Stimuli Captures Attention Automatically: Electrophysiological Evidence

    OpenAIRE

    Marini, Francesco; Marzi, Carlo A.

    2016-01-01

    The visual system leverages organizational regularities of perceptual elements to create meaningful representations of the world. One clear example of such function, which has been formalized in the Gestalt psychology principles, is the perceptual grouping of simple visual elements (e.g., lines and arcs) into unitary objects (e.g., forms and shapes). The present study sought to characterize automatic attentional capture and related cognitive processing of Gestalt-like visual stimuli at the ps...

  7. Measurements and Characterizations of Mechanical Properties of Human Skins

    Science.gov (United States)

    Song, Han Wook; Park, Yon Kyu

    A skin is an indispensible organ for humans because it contributes to metabolism using its own biochemical functions and protects the human body from external stimuli. Recently, mechanical properties such as a thickness, a friction and an elastic coefficient have been used as a decision index in the skin physiology and in the skin care market due to the increased awareness of wellbeing issues. In addition, the use of mechanical properties is known to have good discrimination ability in the classification of human constitutions, which are used in the field of an alternative medicine. In this study, a system that measures mechanical properties such as a friction and an elastic coefficient is designed. The equipment consists of a load cell type (manufactured by the authors) for the measurements of a friction coefficient, a decompression tube for the measurement of an elastic coefficient. Using the proposed system, the mechanical properties of human skins from different constitutions were compared, and the relative repeatability error for measurements of mechanical properties was determined to be less than 2%. Combining the inspection results of medical doctors in the field of an alternative medicine, we could conclude that the proposed system might be applicable to a quantitative constitutional diagnosis between human constitutions within an acceptable level of uncertainty.

  8. Natural Rubber Nanocomposite with Human-Tissue-Like Mechanical Characteristic

    Science.gov (United States)

    Murniati, Riri; Novita, Nanda; Sutisna; Wibowo, Edy; Iskandar, Ferry; Abdullah, Mikrajuddin

    2017-07-01

    The blends of synthetic rubber and natural rubber with nanosilica were prepared using a blending technique in presence of different filler volume fraction. The effect of filler on morphological and mechanical characteristics was studied. Utilization of human cadaver in means of medical study has been commonly used primarily as tools of medical teaching and training such as surgery. Nonetheless, human cadaver brought inevitable problems. So it is necessary to find a substitute material that can be used to replace cadavers. In orthopaedics, the materials that resemble in mechanical properties to biological tissues are elastomers such as natural rubber (latex) and synthetic rubber (polyurethanes, silicones). This substitution material needs to consider the potential of Indonesia to help the development of the nation. Indonesia is the second largest country producer of natural rubber in the world. This paper aims to contribute to adjusting the mechanical properties of tissue-mimicking materials (TMMs) to the recommended range of biological tissue value and thus allow the development of phantoms with greater stability and similarity to human tissues. Repeatability for the phantom fabrication process was also explored. Characteristics were then compared to the control and mechanical characteristics of different human body part tissue. Nanosilica is the best filler to produce the best nanocomposite similarities with human tissue. We produced composites that approaching the properties of human internal tissues.

  9. Differential functioning of Bender Visual-Motor Gestalt Test items.

    Science.gov (United States)

    Sisto, Fermino Fernandes; Dos Santos, Acácia Aparecida Angeli; Noronha, Ana Paula Porto

    2010-02-01

    Differential Item Functioning (DIF) refers to items that do not function the same way for comparable members of different groups. The present study focuses on analyzing and classifying sex-related differential item functioning in the Bender Visual-Motor Gestalt Test. Subjects were 1,052 children attending public schools (513 boys, 539 girls, ages 6-10 years). The protocols were scored using the Bender Graduated Scoring System, which evaluates only the distortion criterion using the Rasch logistic response model. The scoring system fit the Rasch model, although two items were found to be biased by sex. When analyzing differential functioning of items for boys and girls separately, the number of differentially functioning items was equal.

  10. Conflicts and missed signals in psychoanalysis, behaviorism, and Gestalt psychology.

    Science.gov (United States)

    Murray, D J; Kilgour, A R; Wasylkiw, L

    2000-04-01

    At the turn of the 20th century, European psychologists found themselves in conflict situations with respect to the role that private mental states should play in a scientific psychology. Out of this conflict arose 3 of the best-known schools of the 20th century: psychoanalysis, behaviorism, and Gestalt psychology. Each of these schools is discussed with respect to two characteristics. First, the authors discuss the attitude of each school on the meaning of the word unconscious as it was understood around 1900. Second, the authors discuss the influence of each school on the reception accorded to books written around 1900 espousing viewpoints that did not cohere with the school's beliefs. Such books may be considered "missed signals" in the history of psychology. "Hits" associated with each school are also highlighted.

  11. An early history of the Gestalt factors of organisation.

    Science.gov (United States)

    Vezzani, Stefano; Marino, Barbara F M; Giora, Enrico

    2012-01-01

    Wertheimer's (1923, Psychologische Forschung 4 301 - 350) idea that the perceptual world is articulated according to factors of organisation is widely acknowledged as one of the most original contributions of Gestalt psychology and stands as a milestone in the history of vision research. An inquiry focused on the forerunners of some of Wertheimer's factors of perceptual organisation is documented here. In fact, in 1900 Schumann described grouping by proximity and by vertical symmetry, and in 1903 G E Müller identified the factors of sameness/similarity and contour. Other authors contributed to the early description of these factors, such as Rubin, who in 1922 originally illustrated grouping by similarity. Even though Wertheimer himself granted these authors due recognition, later psychologists have paid little attention to their contributions. Some possible reasons for this negligence are briefly discussed.

  12. Ein Integraler Gestalt-Ansatz fuer Therapie und Beratung

    Directory of Open Access Journals (Sweden)

    Martina Gremmler-Fuhr

    2005-06-01

    Full Text Available Zusammenfassung: In diesem Text stellen wir unseren Ansatz für Psychotherapie und Beratung auf dem Hintergrund des integralen Paradigmas dar. Wir erläutern zunächst kurz vier Anforderungen an ein integrales Konzept in diesem professionellen Bereich: Umgang mit Komplexität und Vielperspektivität, Berücksichtigung gerichteter, vieldimensionaler Entwicklung, Orientierungs- und Sinngebungsfunktion, Realisierung relationaler Qualitäten in der Arbeit. Nach einer Begriffsbestimmung von „Therapie“, „Beratung“ und „Bildung“ charakterisieren wir das seit vielen Jahren von uns entwickelte Konzept für den Integralen Gestalt-Ansatz unter den Fragen nach (1 den Intentionen und Aufgaben von Therapie und Beratung, (2 der Gestaltung der Kommunikation und Beziehung, (3 der Art der Problemdefinition und dem Umgang mit Diagnostik sowie (4 den Strategien und Methoden – alle unter Rückkopplung an die zuvor erläuterten Anforderungen an ein integrales Konzept. Abstract: In this text we present our approach to psychotherapy and counseling on the background of the integral paradigm. We shortly explain four major requirements for such an integral concept: handling complexity and multi-perspectivity, considering directed and multi-dimensional development, offering orientation and meaning, relational qualities. After defining the terms „psychotherapy“, „counselling“, and „education“ we present our concept for the Integral Gestalt Approach which we have developed and evaluated for many years by dealing with four questions: (1 the intentions and tasks of therapy and counselling, (2 the formation of communication and relationship, (3 the specific way of defining problems and using diagnostics, and (4 the strategies and methods – all related back to the major requirements of an integral concept.

  13. Conjoining Gestalt Rules for Abstraction of Architectural Drawings%基于格式塔的建筑物图画抽象

    Institute of Scientific and Technical Information of China (English)

    南亮亮; Andrei Sharf; 谢科; Tien-Tsin Wong; Oliver Deussen; Daniel Cohen-Or; 陈宝权

    2012-01-01

    We present a method for structural summarization and abstraction of complex spatial arrangements found in architectural drawings. The method is based on the well-known Gestalt rules, which summarize how forms, patterns, and semantics are perceived by humans from bits and pieces of geometric information. Although defining a computational model for each rule alone has been extensively studied, modeling a conjoint of Gestalt rules remains a challenge. In this work, we develop a computational framework which models Gestalt rules and more importantly, their complex interactions. We apply conjoining rules to line drawings, to detect groups of objects and repetitions that conform to Gestalt principles. We summarize and abstract such groups in ways that maintain structural semantics by displaying only a reduced number of repeated elements, or by replacing them with simpler shapes. We show an application of our method to line drawings of architectural models of various styles, and the potential of extending the technique to other computer-generated illustrations, and three-dimensional models.%格式塔(Gestalt)理论总结了人类认知规则、模式和语义的若干规律,已有大量的研究针对独立的格式塔规则建立计算模型,但建立多个格式塔规则相互作用的耦合模型仍然是一个挑战.基于格式塔理论的若干主要规则建立了一个针对多个格式塔规则耦合的计算模型,并将该模型用于建筑物线画图的抽象;通过减少图画中重复结构元素的数目,或者将复杂的结构用简单结构替换的方式对建筑物结构进行概括和抽象.实验结果表明,该方法可以应用于风格各异的建筑物线画图,并可以扩展到其他类型的图画以及三维模型.

  14. The metaphor-gestalt synergy underlying the self-organisation of perception as a semiotic process.

    Science.gov (United States)

    Rail, David

    2013-04-01

    Recently the basis of concept and language formation has been redefined by the proposal that they both stem from perception and embodiment. The experiential revolution has lead to a far more integrated and dynamic understanding of perception as a semiotic system. The emergence of meaning in the perceptual process stems from the interaction between two key mechanisms. These are first, the generation of schemata through recurrent sensorimotor activity (SM) that underlies category and language formation (L). The second is the interaction between metaphor (M) and gestalt mechanisms (G) that generate invariant mappings beyond the SM domain that both conserve and diversify our understanding and meaning potential. We propose an important advance in our understanding of perception as a semiotic system through exploring the affect of self-organising to criticality where hierarchical behaviour becomes widely integrated through 1/f process and isomorphisms. Our proposal leads to several important implications. First, that SM and L form a functional isomorphism depicted as SM L. We contend that SM L is emergent, corresponding to the phenomenal self. Second, meaning structures the isomorphism SM L through the synergy between M and G (M-G). M-G synergy is based on a combination of structuring and imagination. We contend that the interaction between M-G and SM L functions as a macro-micro comutation that governs perception as semiosis. We discuss how our model relates to current research in fractal time and verb formation.

  15. Interactive Evolutionary Computation for Analyzing Human Awareness Mechanisms

    Directory of Open Access Journals (Sweden)

    Hideyuki Takagi

    2012-01-01

    Full Text Available We discuss the importance of establishing awareness science and show the idea of using interactive evolutionary computation (IEC as a tool for analyzing awareness mechanism and making awareness models. First, we describe the importance of human factors in computational intelligence and that IEC is one of approaches for the so-called humanized computational intelligence. Second, we show examples that IEC is used as an analysis tool for human science. As analyzing human awareness mechanism is in this kind of analyzing human characteristics and capabilities, IEC may be able to be used for this purpose. Based on this expectation, we express one idea for analyzing the awareness mechanism. This idea is to make an equivalent model of an IEC user using a learning model and find latent variables that connect inputs and outputs of the user model and that help to understand or explain the inputs-outputs relationship. Although there must be several definitions of awareness, this idea is based on one definition that awareness is to find out unknown variables that helps our understanding. If we establish a method for finding the latent variables automatically, we can realize an awareness model in computer.

  16. Similarities and Dissimilarities in Coauthorship Networks: Gestalt Theory as Explanation for Well-Ordered Collaboration Structures and Production of Scientific Literature.

    Science.gov (United States)

    Kretschmer, Hildrun

    2002-01-01

    Based on Gestalt theory, the author assumes the existence of a field-force equilibrium to explain how, according to the conciseness principle, mathematically precise gestalts could exist in coauthorship networks. Develops a mathematical function to describe these gestalts in scientific literature and discusses structural characteristics of…

  17. Similarities and Dissimilarities in Coauthorship Networks: Gestalt Theory as Explanation for Well-Ordered Collaboration Structures and Production of Scientific Literature.

    Science.gov (United States)

    Kretschmer, Hildrun

    2002-01-01

    Based on Gestalt theory, the author assumes the existence of a field-force equilibrium to explain how, according to the conciseness principle, mathematically precise gestalts could exist in coauthorship networks. Develops a mathematical function to describe these gestalts in scientific literature and discusses structural characteristics of…

  18. Do clinicians decide relying primarily on Bayesians principles or on Gestalt perception? Some pearls and pitfalls of Gestalt perception in medicine.

    Science.gov (United States)

    Cervellin, Gianfranco; Borghi, Loris; Lippi, Giuseppe

    2014-08-01

    Clinical judgment is a foundation of medical practice and lies at the heart of a physician's knowledge, expertise and skill. Although clinical judgment is an active part of all medical fields, thus including diagnosis and therapy, communication and decision making, it is still poorly defined. It can be considered a synthesis of intuition (mainly based on Gestalt principles) and an analytical approach. Gestalt perception finds its rationale in the evidence that perception of any given object or experience exhibits intrinsic qualities that cannot be completely reduced to visual, auditory, tactile, olfactory, or gustatory components. Thus, perceptions are not constructed in a "bottom-up" fashion from such elements, but are instead globally perceived, in a more "top-down" fashion. Gestalt perception, if cautiously and carefully combined with structured (techno)logical tools, would permit one to defoliate the often too-many-branches built diagnostic trees, and help physicians to better develop their competency. On the other hand, the practice of evidence-based medicine lies in the integration of individual clinical expertise and judgment with the best available external clinical evidence from systematic research. This article is aimed at providing some general concepts about Gestalt perception, and to discuss some aspects of clinical practice potentially influenced by this approach.

  19. Mechanism of toppling instability of the human body in floodwaters

    Science.gov (United States)

    Shu, C. W.; Han, S. S.; Kong, W. N.; Dong, B. L.

    2016-08-01

    Extreme urban flood events occur frequently in China, often leading to heavy casualties. Thus, it is of great importance to study the mechanism of the instability of the human body in floodwaters. The results of such research can provide scientific reference for city flood control standards. In this paper, a formula for the incipient velocity of the human body, during toppling instability in floodwaters, was derived based on mechanical characteristics, instability mechanism, and critical conditions during instability. A series of flume experiments were conducted to investigate the incipient velocity of two 3D printed human body models of different sizes; the resultant experimental data was used to determine parameters in the derived formula. Additionally, grip strength was taken as a standard of a person's ability to withstand floodwaters. Finally, crowd factors were introduced, and based on this study, a criterion for the toppling instability of different subjects in floodwaters was proposed. Compared to the results of previous studies, the proposed formula can better predict the instability of the human body in floodwaters.

  20. An intrinsically safe mechanism for physically coupling humans with robots.

    Science.gov (United States)

    O'Neill, Gerald; Patel, Harshil; Artemiadis, Panagiotis

    2013-06-01

    Robots are increasingly used in tasks that include physical interaction with humans. Examples can be found in the area of rehabilitation robotics, power augmentation robots, as well as assistive and orthotic devices. However, current methods of physically coupling humans with robots fail to provide intrinsic safety, adaptation and efficiency, which limit the application of wearable robotics only to laboratory and controlled environments. In this paper we present the design and verification of a novel mechanism for physically coupling humans and robots. The device is intrinsically safe, since it is based on passive, non-electric features that are not prone to malfunctions. The device is capable of transmitting forces and torques in all directions between the human user and the robot. Moreover, its re-configurable nature allows for easy and consistent adjustment of the decoupling force. The latter makes the mechanism applicable to a wide range of human-robot coupling applications, ranging from low-force rehabilitation-therapy scenarios to high-force augmentation cases.

  1. Cytotoxinic Mechanism of Hydroxyapatite Nanoparticles on Human Hepatoma Cell Lines

    Institute of Scientific and Technical Information of China (English)

    CAO Xian-ying; QI Zhi-tao; DAI Hong-lian; YAN Yu-hua; LI Shi-pu

    2003-01-01

    Stable and single-dispersed HAP nanoparticles were synthesized with chemical method assisted by ultrasonic treatment.HAP nanoparticles were surveyed by AFM and Zataplus.The effect on the Bel-7402 human hepatoma cell lines treated with HAP nanoparticles was investigated by the MTT methods and observation of morphology,and the mechanism was studied in changes of cell cycle and ultrastructure.The result shows that inhibition of HAP nanoparticles on the Bel-7402 human hepatoma cell lines is obviously in vitro.HAP nanoparticles the entered cancer cytoplasm,and cell proliferation is stopped at G1 phase of cell cycle,thus,cancer cells die directly.

  2. Correlation of the Scores on Barron's Ego Strength Scale with the Scores on the Bender-Gestalt Test.

    Science.gov (United States)

    Martin, John D.; And Others

    1979-01-01

    The degree of relationship between scores on the Barron Ego Strength Scale and the scores on the Bender-Gestalt Test was investigated on a sample of college students. Correlations were moderate to low. Racial differences were observed on the Bender-Gestalt Test. (Author/JKS)

  3. Comparison of the Qualitative and Developmental Scoring Systems for the Modified Version of the Bender-Gestalt Test.

    Science.gov (United States)

    Brannigan, Gary G.; Brunner, Nancy A.

    1993-01-01

    Examined two scoring systems for Modified Version of the Bender-Gestalt Test. Administered Bender-Gestalt and Otis-Lennon School Ability Test to 75 first-grade and 84 second-grade students. Both systems were significantly correlated with school ability. Results of tests for differences between correlations indicated that Qualitative Scoring System…

  4. The Performance of Learning Disabled Children on the Kaufman Assessment Battery for Children and the Bender-Gestalt Test.

    Science.gov (United States)

    Haddad, Frederick A.

    1986-01-01

    Results of the Kaufman Assessment Battery for Children (K-ABC) and Bender-Gestalt Test were compared for a sample of learning disabled children that included 24 blacks and 24 whites; mean age 9 years. A significant correlation coefficient was found between the K-ABC Simultaneous Scale and the Bender-Gestalt Test error score. Implications of these…

  5. Grouping in object recognition: the role of a Gestalt law in letter identification.

    Science.gov (United States)

    Pelli, Denis G; Majaj, Najib J; Raizman, Noah; Christian, Christopher J; Kim, Edward; Palomares, Melanie C

    2009-02-01

    The Gestalt psychologists reported a set of laws describing how vision groups elements to recognize objects. The Gestalt laws "prescribe for us what we are to recognize 'as one thing'" (Kohler, 1920). Were they right? Does object recognition involve grouping? Tests of the laws of grouping have been favourable, but mostly assessed only detection, not identification, of the compound object. The grouping of elements seen in the detection experiments with lattices and "snakes in the grass" is compelling, but falls far short of the vivid everyday experience of recognizing a familiar, meaningful, named thing, which mediates the ordinary identification of an object. Thus, after nearly a century, there is hardly any evidence that grouping plays a role in ordinary object recognition. To assess grouping in object recognition, we made letters out of grating patches and measured threshold contrast for identifying these letters in visual noise as a function of perturbation of grating orientation, phase, and offset. We define a new measure, "wiggle", to characterize the degree to which these various perturbations violate the Gestalt law of good continuation. We find that efficiency for letter identification is inversely proportional to wiggle and is wholly determined by wiggle, independent of how the wiggle was produced. Thus the effects of three different kinds of shape perturbation on letter identifiability are predicted by a single measure of goodness of continuation. This shows that letter identification obeys the Gestalt law of good continuation and may be the first confirmation of the original Gestalt claim that object recognition involves grouping.

  6. Mechanisms for training security inspectors to enhance human performance

    Energy Technology Data Exchange (ETDEWEB)

    Burkhalter, H.E.; Sessions, J.C.

    1988-01-01

    The Department of Energy (DOE) has established qualification standards for protective force personnel employed at nuclear facilities (10 CFR Part 1046 (Federal Register)). Training mechanisms used at Los Alamos to enhance human performance in meeting DOE standards include, but are not limited to, the following: for cardio-respiratory training, they utilize distance running, interval training, sprint training, pacing, indoor aerobics and circuit training; for muscular strength, free weights, weight machines, light hand weights, grip strength conditioners, and calistenics are employed; for muscular endurance, participants do high repetitions (15 - 40) using dumbbells, flex weights, resistive rubber bands, benches, and calisthenics; for flexibility, each training session devotes specific times to stretch the muscles involved for a particular activity. These training mechanisms with specific protocols can enhance human performance.

  7. INTEGRATION MECHANISMS OF IMPROVEMENT OF HUMAN RESOURCES MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Vera A. Akimenko

    2013-01-01

    Full Text Available In the current economic conditions, the efficiency of business processes of an organization is determined by the quality of the staff. Therefore, actual is the creation and application of new approaches to the management of human re-sources. The article presents a comparative analysis of management practices and their impact on the effectiveness of personnel management, the mechanism of their integration to improve the efficiency of the process.

  8. Bioactive proteins in human milk: mechanisms of action.

    Science.gov (United States)

    Lönnerdal, Bo

    2010-02-01

    Human milk contains a multitude of bioactive proteins, with very diverse functions. Some of these proteins are involved in the synthesis and expression of milk, but the majority appears to have evolved to provide physiological activities in the breast-fed infant. These activities are exerted by a wide variety of mechanisms and have largely been unraveled by in vitro studies. To be active in the gastrointestinal tract, these proteins must be able to resist proteolytic degradation, at least for some time. We have evaluated the human milk proteins lactoferrin, haptocorrin, alpha(1)-antitrypsin, and transforming growth factor -beta in an in vitro digestion model, mimicking the conditions of the infant gastrointestinal milieu. These bioactive proteins are resistant against proteolysis and can remain intact or as larger fragments through passage of the gastrointestinal tract. In vitro digestibility assays can be helpful to assess which human milk proteins can resist proteolysis and to what extent.

  9. The mechanism of gene targeting in human somatic cells.

    Directory of Open Access Journals (Sweden)

    Yinan Kan

    2014-04-01

    Full Text Available Gene targeting in human somatic cells is of importance because it can be used to either delineate the loss-of-function phenotype of a gene or correct a mutated gene back to wild-type. Both of these outcomes require a form of DNA double-strand break (DSB repair known as homologous recombination (HR. The mechanism of HR leading to gene targeting, however, is not well understood in human cells. Here, we demonstrate that a two-end, ends-out HR intermediate is valid for human gene targeting. Furthermore, the resolution step of this intermediate occurs via the classic DSB repair model of HR while synthesis-dependent strand annealing and Holliday Junction dissolution are, at best, minor pathways. Moreover, and in contrast to other systems, the positions of Holliday Junction resolution are evenly distributed along the homology arms of the targeting vector. Most unexpectedly, we demonstrate that when a meganuclease is used to introduce a chromosomal DSB to augment gene targeting, the mechanism of gene targeting is inverted to an ends-in process. Finally, we demonstrate that the anti-recombination activity of mismatch repair is a significant impediment to gene targeting. These observations significantly advance our understanding of HR and gene targeting in human cells.

  10. The mechanism of gene targeting in human somatic cells.

    Science.gov (United States)

    Kan, Yinan; Ruis, Brian; Lin, Sherry; Hendrickson, Eric A

    2014-04-01

    Gene targeting in human somatic cells is of importance because it can be used to either delineate the loss-of-function phenotype of a gene or correct a mutated gene back to wild-type. Both of these outcomes require a form of DNA double-strand break (DSB) repair known as homologous recombination (HR). The mechanism of HR leading to gene targeting, however, is not well understood in human cells. Here, we demonstrate that a two-end, ends-out HR intermediate is valid for human gene targeting. Furthermore, the resolution step of this intermediate occurs via the classic DSB repair model of HR while synthesis-dependent strand annealing and Holliday Junction dissolution are, at best, minor pathways. Moreover, and in contrast to other systems, the positions of Holliday Junction resolution are evenly distributed along the homology arms of the targeting vector. Most unexpectedly, we demonstrate that when a meganuclease is used to introduce a chromosomal DSB to augment gene targeting, the mechanism of gene targeting is inverted to an ends-in process. Finally, we demonstrate that the anti-recombination activity of mismatch repair is a significant impediment to gene targeting. These observations significantly advance our understanding of HR and gene targeting in human cells.

  11. Perception of Border Ownership by Multiple Gestalt Factors

    Directory of Open Access Journals (Sweden)

    Shohei Matsuoka

    2012-10-01

    Full Text Available Gestalt factors such as convexity, closure, and size promote the perception of the direction of figure. Although recent studies have investigated the effects of the individual factors, it has not been clarified how these factors interact with each other, when the features coexist in a local contour. In the present study, we examined psychophysically the interaction of convexity and closure that coexist in a local contour of natural image. First, we established the quantification of convexity and closure (indices to represent the factors for contours of natural images. By using these quantities, we selected a set of local contours that includes a uniform and wide variation of convexity and closure. Second, we performed a psychophysical experiment to measure the apparent direction of figure for the set of local contours. The result showed that the perceived direction of figure tends to agree with the direction of closure when both convexity and closure coexist in a local contour. The result also showed that while the direction of closure dominates the perception of the direction of figure, the index of closure does not correlate linearly with the perceptual judgment. These results suggest that the perceptual judgment of the direction of figure depends mostly on closure when it coexists with convexity, and that the dependence is dichotomic; two contours with different degrees of closure do not evoke distinct perception. Closure appears to be a dominant and strong cue for the direction of figure.

  12. A Gestalt approach to Gram-negative entry.

    Science.gov (United States)

    Silver, Lynn L

    2016-12-15

    A major obstacle confronting the discovery and development of new antibacterial agents to combat resistant Gram-negative (GN) organisms is the lack of a rational process for endowing compounds with properties that allow (or promote) entry into the bacterial cytoplasm. The major permeability difference between GN and Gram-positive (GP) bacteria is the GN outer membrane (OM) which is a permeability barrier itself and potentiates efflux pumps that expel compounds. Based on the fact that OM-permeable and efflux-deleted GNs are sensitive to many anti-GP drugs, recent efforts to approach the GN entry problem have focused on ways of avoiding efflux and transiting or compromising the OM, with the tacit assumption that this could allow entry of compounds into the GN cytoplasm. But bypassing the OM and efflux obstacles does not take into account the additional requirement of penetrating the cytoplasmic membrane (CM) whose sieving properties appear to be orthogonal to that of the OM. That is, tailoring compounds to transit the OM may well compromise their ability to enter the cytoplasm. Thus, a Gestalt approach to understanding the chemical requirements for GN entry seems a useful adjunct. This might consist of characterizing compounds which reach the cytoplasm, grouping (or binning) by routes of entry and formulating chemical 'rules' for those bins. This will require acquisition of data on large numbers of compounds, using non-activity-dependent methods of measuring accumulation in the cytoplasm. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Gestalt grouping via closure degrades suprathreshold depth percepts.

    Science.gov (United States)

    Deas, Lesley M; Wilcox, Laurie M

    2014-08-19

    It is well known that the perception of depth is susceptible to changes in configuration. For example, stereoscopic precision for a pair of vertical lines can be dramatically reduced when these lines are connected to form a closed object. Here, we extend this paradigm to suprathreshold estimates of perceived depth. Using a touch-sensor, observers made quantitative estimates of depth between a vertical line pair presented in isolation or as edges of a closed rectangular object with different figural interpretations. First, we show that the amount of depth estimated within a closed rectangular object is consistently reduced relative to the vertical edges presented in isolation or when they form the edges of two segmented objects. We then demonstrate that the reduction in perceived depth for closed objects is modulated by manipulations that influence perceived closure of the central figure. Depth percepts were most disrupted when the horizontal connectors and vertical lines matched in color. Perceived depth increased slightly when the connectors had opposite contrast polarity, but increased dramatically when flankers were added. Thus, as grouping cues were added to counter the interpretation of a closed object, the depth degradation effect was systematically eliminated. The configurations tested here rule out explanations based on early, local interactions such as inhibition or cue conflict; instead, our results provide strong evidence of the impact of Gestalt grouping, via closure, on depth magnitude percepts from stereopsis. © 2014 ARVO.

  14. Robotic Powered Transfer Mechanism modeling on Human Muscle Structure

    Science.gov (United States)

    Saito, Yukio

    It is considered in engineering that one power source can operate one joint. However, support movement mechanism of living organism is multi joint movement mechanism. Considerably different from mechanical movement mechanism, two pairs of uni-articular muscles and a pair of bi-articular muscles are involved in it. In leg, movements observed in short run including leg idling, heel contact and toeing are operated by bi-articular muscles of the thigh showing strong legs to support body weight. Pursuit of versatility in welfare robot brings its comparison with conventional machinery or industrial robot to the fore. Request for safety and technology allowing elderly people to operate the robot is getting stronger in the society. The robot must be safe when it is used together with other welfare equipment and simpler system avoiding difficult operation has to be constructed. Appearance of recent care and assistance robot is getting similar to human arm in comparison with industrial robot. Being easily able to imagine from industrial robot, mid-heavyweight articulated robot to support 60-70kgf combined with large output motor and reduction gears is next to impossible to be installed in the bath room. This research indicated that upper limb arm and lower limb thigh of human and animals are holding coalitional muscles and movement of uni-artcular muscle and bi-articular muscle conjure the image of new actuators.

  15. The mechanical properties of the human hip capsule ligaments.

    Science.gov (United States)

    Hewitt, John D; Glisson, Richard R; Guilak, Farshid; Vail, T Parker

    2002-01-01

    The human hip capsule is adapted to facilitate upright posture, joint stability, and ambulation, yet it routinely is excised in hip surgery without a full understanding of its mechanical contributions. The objective of this study was to provide information about the mechanical properties of the ligaments that form the hip capsule. Cadaver bone-ligament-bone specimens of the iliofemoral, ischiofemoral, and femoral arcuate ligaments were tested to failure in tension. The hip capsule was found to be an inhomogeneous structure and should be recognized as being composed of discrete constituent ligaments. The anterior ligaments, consisting of the 2 arms of the iliofemoral ligament, were much stronger than the posterior ischiofemoral ligament, withstanding greater force at failure and exhibiting greater stiffness. Knowledge of the anatomy and mechanical properties of the capsule may help the hip surgeon choose an appropriate surgical approach or repair strategy.

  16. Mechanisms of human immunodeficiency virus type 2 RNA packaging

    DEFF Research Database (Denmark)

    Ni, Na; Nikolaitchik, Olga A; Dilley, Kari A;

    2011-01-01

    Human immunodeficiency virus type 2 (HIV-2) has been reported to have a distinct RNA packaging mechanism, referred to as cis packaging, in which Gag proteins package the RNA from which they were translated. We examined the progeny generated from dually infected cell lines that contain two HIV-2...... proviruses, one with a wild-type gag/gag-pol and the other with a mutant gag that cannot express functional Gag/Gag-Pol. Viral titers and RNA analyses revealed that mutant viral RNAs can be packaged at efficiencies comparable to that of viral RNA from which wild-type Gag/Gag-Pol is translated. These results...... do not support the cis-packaging hypothesis but instead indicate that trans packaging is the major mechanism of HIV-2 RNA packaging. To further characterize the mechanisms of HIV-2 RNA packaging, we visualized HIV-2 RNA in individual particles by using fluorescent protein-tagged RNA-binding proteins...

  17. Role of Gestalt grouping in selective attention: evidence from the Stroop task.

    Science.gov (United States)

    Lamers, Martijn J M; Roelofs, Ardi

    2007-11-01

    Selective attention has been intensively studied using the Stroop task. Evidence suggests that Stroop interference in a color-naming task arises partly because of visual attention sharing between color and word: Removing the target color after 150 msec reduces interference (Neumann, 1986). Moreover, removing both the color and the word simultaneously reduces interference less than does removing the color only (La Heij, van der Heijden, & Plooij, 2001). These findings could also be attributed to Gestalt grouping principles, such as common fate. We report three experiments in which the role of Gestalt grouping was further investigated. Experiment I replicated the reduced interference, using words and color patches. In Experiment 2, the color patch was not removed but only repositioned (Gestalt grouping in selective attention.

  18. The Bender-Gestalt with adolescents: comparison of two scoring systems.

    Science.gov (United States)

    McIntosh, J A; Belter, R W; Saylor, C F; Finch, A J; Edwards, G L

    1988-03-01

    The present study was designed to evaluate the relative efficacy of two different scoring systems (Koppitz, 1975; Lacks, 1984) for use in evaluating Bender-Gestalt performance by adolescents. Normative data are presented for the two scoring systems with a sample of "normal" controls (N = 150), emotionally disturbed (N = 140), and mentally retarded/neurologically impaired adolescents (N = 47), aged 12-17. Results suggested that age and psychopathology were not related to the quality of the Bender-Gestalt reproductions of these subjects. An inverse relationship was found between cognitive ability and visual motor skills. Data obtained from these samples of adolescents showed a high degree of consistency between the scoring systems, which suggests that either scoring procedure is suitable for evaluating the Bender-Gestalt performance of adolescents.

  19. A Gestalt-terapia na universidade: da f(ô)rma à boa forma

    OpenAIRE

    Luciana Loyola Madeira Soares

    2009-01-01

    Este texto apresenta uma discussão sobre as características do trabalho de supervisão em Gestalt-terapia nos Serviços de Psicologia Aplicada dos cursos de graduação em Psicologia. Com uma presença que ainda pode ser considerada recente na universidade, a Gestalt-terapia propõe uma abordagem no estágio em Psicologia Clínica que não se confunde com uma formação de gestalt-terapeutas. Sua estratégia passa pelo desdobramento de possibilidades criativas da relação do supervisor com o estagiário e,...

  20. Turkish children's Bender-Gestalt test performance: differences in public and private school children.

    Science.gov (United States)

    Ozer, Serap

    2011-02-01

    The present study was undertaken to provide data on the Bender-Gestalt test for children aged 5 to 11 in Turkey. Although it is well documented that sociocultural factors are important in cognitive evaluations, the effects of type of school and differing educational opportunities provided by these schools on the Bender-Gestalt test have not been previously investigated. The aim of the present study was to investigate the effect of age, sex, and school type on Bender-Gestalt performance. The test was individually administered to 484 children between the ages of 5 and 11 years. The children were enrolled in either public or private schools. Koppitz's Developmental Scoring System was utilized. The results indicated that older children performed with fewer errors. Girls performed with fewer errors than boys. Finally, as expected, private school children outperformed their public school peers. The results are discussed with respect to the importance of taking into account various educational factors in utilizing commonly used tests.

  1. Mechanism of resveratrol-induced relaxation in the human gallbladder.

    Science.gov (United States)

    Tsai, Ching-Chung; Lee, Ming-Che; Tey, Shu-Leei; Liu, Ching-Wen; Huang, Shih-Che

    2017-05-08

    Resveratrol is a polyphenolic compound extracted from plants and is also a constituent of red wine. Resveratrol produces relaxation of vascular smooth muscle and may prevent cardiovascular diseases. Although resveratrol has been reported to cause relaxation of the guinea pig gallbladder, limited data are available about the effect of resveratrol on the gallbladder smooth muscle in humans. The purpose of this study was to investigate the relaxation effects of resveratrol in human gallbladder muscle strips. We studied the relaxant effects of resveratrol in human gallbladder. In addition, we also investigated mechanism of resveratrol-induced relaxation in human gallbladder by tetraethylammonium (a non-selective potassium channels blocker), iberiotoxin (an inhibitor of large conductance calcium-activated potassium channel), glibenclamide (an ATP-sensitive potassium channel blocker), charybdotoxin (an inhibitor of large conductance calcium-activated potassium channels and slowly inactivating voltage-gated potassium channels), apamine (a selective inhibitor of the small conductance calcium-activated potassium channel), KT 5720 (a cAMP-dependent protein kinase A inhibitor), KT 5823 (a cGMP-dependent protein kinase G inhibitor), NG-Nitro-L-arginine (a competitive inhibitor of nitric oxide synthase), tetrodotoxin (a selective neuronal Na(+) channel blocker), and ω-conotoxin GVIA (a selective neuronal Ca(2+) channel blocker). The present study showed that resveratrol has relaxant effects in human gallbladder muscle strips. In addition, we found that resveratrol-induced relaxation in human gallbladder is associated with nitric oxide, ATP-sensitive potassium channel, and large conductance calcium-activated potassium channel pathways. This study provides the first evidence concerning the relaxant effects of resveratrol in human gallbladder muscle strips. Furthermore, these results demonstrate that resveratrol is a potential new drug or health supplement in the treatment of

  2. Neuropsychological assessment with the Visual Gestalt Test: psychometric properties and differential diagnostic probabilities.

    Science.gov (United States)

    la Cour, Peter; Andersen, Ruth

    2006-02-01

    The Visual Gestalt Test is a neuropsychological instrument developed for evaluation of learning and memory of visuo-spatial material. A revised strategy of scoring has motivated the present study, where data from 153 normal persons, 99 epilepsy patients, and 24 depressed patients are presented and compared. The Visual Gestalt Test is observed to discriminate between normal and diagnosed groups in several ways. Additionally it is found to discriminate between depressed and brain damage subgroups of patients. Data are presented in order to supplement previously published ways of scoring and norms. Practical guidelines for the clinical applications of the test are suggested as perspectives.

  3. A Gestalt music analysis : philosophical theory, method, and analysis of Iegor Reznikoff's compositions

    OpenAIRE

    Utriainen, Jaana

    2005-01-01

    Jaana Utriainen on väitöskirjassaan luonut hahmofilosofisen musiikkianalyysiteorian ja –metodin GMAn (A Gestalt Music Analysis) ja soveltanut sitä ranskalaisen Iégor Reznikoffin neljään laulusävellykseen.- Etsin vastauksia väitteelle, jonka mukaan sävellyksistä on analysoitavissa ja tulkittavissa säveltäjän luova musiikillinen hahmoprosessi eli säveltäjän sisäinen musiikillinen hahmo. Lisäksi muodostin analyysimallin, jonka avulla musiikin hahmon laatu (Gestalt Quality) voidaan analysoida ja ...

  4. Gestalt Intervention Groups for Anxious Parents in Hong Kong: A Quasi-Experimental Design.

    Science.gov (United States)

    Leung, Grace Suk Man; Khor, Su Hean

    2017-01-01

    This study examined the impact of gestalt intervention groups for anxious Chinese parents in Hong Kong. A non-randomized control group pre-test/post-test design was adopted. A total of 156 parents participated in the project. After 4 weeks of treatment, the intervention group participants had lower anxiety levels, less avoidance of inner experiences, and more kindness towards oneself and mindfulness when compared to control group participants. However, the dimension of self-judgment remained unchanged. The adaptation of gestalt intervention to suit the Chinese culture was discussed.

  5. Secondary Mechanisms of Affinity Maturation in the Human Antibody Repertoire

    Directory of Open Access Journals (Sweden)

    Bryan S. Briney

    2013-03-01

    Full Text Available V(DJ recombination and somatic hypermutation (SHM are the primary mechanisms for diversification of the human antibody repertoire. These mechanisms allow for rapid humoral immune responses to a wide range of pathogenic challenges. V(DJ recombination efficiently generate a virtually limitless diversity through random recombination of variable (V, diversity (D and joining (J genes with diverse nontemplated junctions between the selected gene segments. Following antigen stimulation, affinity maturation by SHM produces antibodies with refined specificity mediated by mutations typically focused in complementarity determining regions (CDRs, which form the bulk of the antigen recognition site. While V(DJ recombination and SHM are responsible for much of the diversity of the antibody repertoire, there are several secondary mechanisms that, while less frequent, make substantial contributions to antibody diversity including V(DDJ recombination (or D-D fusion, somatic-hypermutation-associated insertions and deletions, and affinity maturation and antigen contact by non-CDR regions of the antibody. In addition to enhanced diversity, these mechanisms allow the production of antibodies that are critical to response to a variety of viral and bacterial pathogens but that would be difficult to generate using only the primary mechanisms of diversification.

  6. Biomechanical Analysis of Force Distribution in Human Finger Extensor Mechanisms

    Directory of Open Access Journals (Sweden)

    Dan Hu

    2014-01-01

    Full Text Available The complexities of the function and structure of human fingers have long been recognised. The in vivo forces in the human finger tendon network during different activities are critical information for clinical diagnosis, surgical treatment, prosthetic finger design, and biomimetic hand development. In this study, we propose a novel method for in vivo force estimation for the finger tendon network by combining a three-dimensional motion analysis technique and a novel biomechanical tendon network model. The extensor mechanism of a human index finger is represented by an interconnected tendinous network moving around the phalanx’s dorsum. A novel analytical approach based on the “Principle of Minimum Total Potential Energy” is used to calculate the forces and deformations throughout the tendon network of the extensor mechanism when subjected to an external load and with the finger posture defined by measurement data. The predicted deformations and forces in the tendon network are in broad agreement with the results obtained by previous experimental in vitro studies. The proposed methodology provides a promising tool for investigating the biomechanical function of complex interconnected tendon networks in vivo.

  7. Integration of Social Sciences and Humanities into Mechanical Engineering Curriculum

    Directory of Open Access Journals (Sweden)

    Nikša Dubreta

    2014-04-01

    Full Text Available Article deals with ways in which social sciences and humanities have been integrated from the 1980s to the present day into curriculum of Faculty of Mechanical Engineering and Naval Architecture at University of Zagreb, Croatia. After a brief review and summary of selected research and theoretical contributions to the subject theme, a specific research setting is indicated and contextualized. Elements of socio-historical approach are established primarily through analysis of corresponding documents: curriculums from the 1980s, 1990s and 2000s and from key documents on strategic development of the Faculty. It is stressed that social sciences and humanities topics are continually represented in mechanical engineering study program as legitimate, but separate unit, poorly integrated in the main engineering courses. Together with more or less expressed orientation toward micro-social and micro-economical issues in industry and business, it points to the main features in continuity of establishing the field of social sciences and humanities. Finally, it is shown that chances to widen and enrich aforementioned field are in close relation to the character of engineering and its social contextualization expressed in a key Faculty’s strategic documents.

  8. Gestalt-like constraints produce veridical (Euclidean) percepts of 3D indoor scenes.

    Science.gov (United States)

    Kwon, TaeKyu; Li, Yunfeng; Sawada, Tadamasa; Pizlo, Zygmunt

    2016-09-01

    This study, which was influenced a lot by Gestalt ideas, extends our prior work on the role of a priori constraints in the veridical perception of 3D shapes to the perception of 3D scenes. Our experiments tested how human subjects perceive the layout of a naturally-illuminated indoor scene that contains common symmetrical 3D objects standing on a horizontal floor. In one task, the subject was asked to draw a top view of a scene that was viewed either monocularly or binocularly. The top views the subjects reconstructed were configured accurately except for their overall size. These size errors varied from trial to trial, and were shown most-likely to result from the presence of a response bias. There was little, if any, evidence of systematic distortions of the subjects' perceived visual space, the kind of distortions that have been reported in numerous experiments run under very unnatural conditions. This shown, we proceeded to use Foley's (Vision Research 12 (1972) 323-332) isosceles right triangle experiment to test the intrinsic geometry of visual space directly. This was done with natural viewing, with the impoverished viewing conditions Foley had used, as well as with a number of intermediate viewing conditions. Our subjects produced very accurate triangles when the viewing conditions were natural, but their performance deteriorated systematically as the viewing conditions were progressively impoverished. Their perception of visual space became more compressed as their natural visual environment was degraded. Once this was shown, we developed a computational model that emulated the most salient features of our psychophysical results. We concluded that human observers see 3D scenes veridically when they view natural 3D objects within natural 3D environments. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. A current genetic and epigenetic view on human aging mechanisms.

    Science.gov (United States)

    Ostojić, Sala; Pereza, Nina; Kapović, Miljenko

    2009-06-01

    The process of aging is one of the most complex and intriguing biological phenomenons. Aging is a genetically regulated process in which the organism's maximum lifespan potential is pre-determined, while the rate of aging is influenced by environmental factors and lifestyle. Considering the complexity of mechanisms involved in the regulation of aging process, up to this date there isn't a major, unifying theory which could explain them. As genetic/epigenetic and environmental factors both inevitably influence the aging process, here we present a review on the genetic and epigenetic regulation of the most important molecular and cellular mechanisms involved in the process of aging. Based on the studies on oxidative stress, metabolism, genome stability, epigenetic modifications and cellular senescence in animal models and humans, we give an overview of key genetic and molecular pathways related to aging. As most of genetic manipulations which influence the aging process also affect reproduction, we discuss aging in humans as a post-reproductive genetically determined process. After the age of reproductive success, aging continously progresses which clinically coincides with the onset of most chronic diseases, cancers and dementions. As evolution shapes the genomes for reproductive success and not for post-reproductive survival, aging could be defined as a protective mechanism which ensures the preservation and progress of species through the modification, trasmission and improvement of genetic material.

  10. Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6

    Science.gov (United States)

    Huang, Jo-Hsi; Ku, Wei-Chi; Chen, Yen-Chun; Chang, Yi-Ling; Chu, Chia-Ying

    2017-01-01

    DDX6 is a conserved DEAD-box protein (DBP) that plays central roles in cytoplasmic RNA regulation, including processing body (P-body) assembly, mRNA decapping, and translational repression. Beyond its cytoplasmic functions, DDX6 may also have nuclear functions because its orthologues are known to localize to nuclei in several biological contexts. However, it is unclear whether DDX6 is generally present in human cell nuclei, and the molecular mechanism underlying DDX6 subcellular distribution remains elusive. In this study, we showed that DDX6 is commonly present in the nuclei of human-derived cells. Our structural and molecular analyses deviate from the current model that the shuttling of DDX6 is directly mediated by the canonical nuclear localization signal (NLS) and nuclear export signal (NES), which are recognized and transported by Importin-α/β and CRM1, respectively. Instead, we show that DDX6 can be transported by 4E-T in a piggyback manner. Furthermore, we provide evidence for a novel nuclear targeting mechanism in which DDX6 enters the newly formed nuclei by “hitch-hiking” on mitotic chromosomes with its C-terminal domain during M phase progression. Together, our results indicate that the nucleocytoplasmic localization of DDX6 is regulated by these dual mechanisms. PMID:28216671

  11. Sex hormone effects on autonomic mechanisms of thermoregulation in humans.

    Science.gov (United States)

    Charkoudian, Nisha; Stachenfeld, Nina

    2016-04-01

    Autonomic mechanisms are fundamental to human physiological thermoregulation, and female reproductive hormones have substantial influences on several aspects of these mechanisms. Of these, the best recognized are the thermoregulatory responses that occur at menopause (hot flushes) and the changes in body temperature within the menstrual cycle which may help couples predict ovulation. Our goal in this brief review is to summarize current knowledge regarding the influences of reproductive hormones on autonomic mechanisms in human thermoregulation. In general, estrogens tend to promote lower body temperatures via augmentation of heat dissipation responses, whereas progesterone tends to promote higher body temperatures. Recent evidence suggests specific influences of estrogens on central autonomic nuclei involved in control of skin blood flow and sweating. Estrogens also augment vasodilation by direct effects on peripheral blood vessels. Influences of progesterone are less well understood, but include both centrally regulated changes in thermoregulatory set-point as well as and peripheral effects, including augmented vasoconstriction in the skin. We conclude with a brief discussion of thermoregulatory adjustments associated with changing hormone levels during menopause, pregnancy and polycystic ovary syndrome. Published by Elsevier B.V.

  12. Ketamine inhibits human sperm function by Ca(2+)-related mechanism.

    Science.gov (United States)

    He, Yuanqiao; Zou, Qianxing; Li, Bingda; Chen, Houyang; Du, Xiaohong; Weng, Shiqi; Luo, Tao; Zeng, Xuhui

    2016-09-09

    Ketamine, a dissociative anesthetic, which was widely used in human and animal medicine, has become a popular recreational drug, as it can induce hallucinatory effects. Ketamine abuse can cause serious damage to many aspects of the organism, mainly reflected in the nervous system and urinary system. It has also been reported that ketamine can impair the male genital system. However, the detailed effect of ketamine on human spermatozoa remains unclear. Thus, we investigated the in vitro effects of ketamine on human sperm functions, to elucidate the underlying mechanism. Human sperm were treated in vitro with different concentrations of ketamine (0, 0.125, 0.25, 0.5, 1 g/L). The results showed that 0.25-1 g/L ketamine inhibited sperm total motility, progressive motility and linear velocity, in a dose-dependent manner. In addition, the sperm's ability to penetrate viscous medium and the progesterone-induced acrosome reaction were significantly inhibited by ketamine. Ketamine did not affect sperm viability, capacitation and spontaneous acrosome reaction. The intracellular calcium concentration ([Ca(2+)]i), which is a central factor in the regulation of human sperm function, was decreased by ketamine (0.125-1 g/L) in a dose-dependent manner. Furthermore, the currents of the sperm-specific Ca(2+) channel, CatSper, which modulates Ca(2+) influx in sperm, were inhibited by ketamine (0.125-1 g/L) in a dose-dependent manner. Our findings suggest that ketamine induces its toxic effects on human sperm functions by reducing sperm [Ca(2+)]i through inhibition of CatSper channel. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Beyond membrane channelopathies: alternative mechanisms underlying complex human disease

    Institute of Scientific and Technical Information of China (English)

    Konstantinos Dean BOUDOULAS; Peter J MOHLER

    2011-01-01

    Over the past fifteen years, our understanding of the molecular mechanisms underlying human disease has flourished in large part due to the discovery of gene mutations linked with membrane ion channels and transporters. In fact, ion channel defects ("channelopathies" - the focus of this review series) have been associated with a spectrum of serious human disease phenotypes including cystic fibrosis, cardiac arrhythmia, diabetes, skeletal muscle defects, and neurological disorders. However, we now know that human disease, particularly excitable cell disease, may be caused by defects in non-ion channel polypeptides including in cellular components residing well beneath the plasma membrane. For example, over the past few years, a new class of potentially fatal cardiac arrhythmias has been linked with cytoplasmic proteins that include sub-membrane adapters such as ankyrin-B (ANK2),ankyrin-G (ANK3), and alpha-1 syntrophin, membrane coat proteins including caveolin-3 (CAV3), signaling platforms including yotiao (AKAPg), and cardiac enzymes (GPD1L). The focus of this review is to detail the exciting role of lamins, yet another class of gene products that have provided elegant new insight into human disease.

  14. Implementing Human-like Intuition Mechanism in Artificial Intelligence

    CERN Document Server

    Dundas, Jitesh

    2011-01-01

    Human intuition has been simulated by several research projects using artificial intelligence techniques. Most of these algorithms or models lack the ability to handle complications or diversions. Moreover, they also do not explain the factors influencing intuition and the accuracy of the results from this process. In this paper, we present a simple series based model for implementation of human-like intuition using the principles of connectivity and unknown entities. By using Poker hand datasets and Car evaluation datasets, we compare the performance of some well-known models with our intuition model. The aim of the experiment was to predict the maximum accurate answers using intuition based models. We found that the presence of unknown entities, diversion from the current problem scenario, and identifying weakness without the normal logic based execution, greatly affects the reliability of the answers. Generally, the intuition based models cannot be a substitute for the logic based mechanisms in handling su...

  15. [Reaction mechanism of cefotaxime with human serum albumin].

    Science.gov (United States)

    Liu, Luo-sheng; Wang, Xing-po; Zhao, Quan-qin; Zhang, Yu-yi

    2006-06-01

    The reaction mechanism of cefotaxime with human serum albumin (HSA) and the affinity between cefotaxime and beta-lactamase were investigated by spectrometry and spectrofluorimetry. The interaction dissociation constants of human serum albumin and cefotaxime were determined from a double reciprocal Lineweaver-Burk plot. The binding distance and transfer efficiency between cefotaxime and HSA were also obtained according to the theory of Förster non-radiation energy transfer. The result suggested that the main binding force between cefotaxime and HSA is electrostatic force interaction. The high beta-lactamase stability of cefotaxime may be correlative with its molecular structure. The antibiotic activity and valence are connected with transfer efficiency and dissociation constant. The effect of cefotaxime on the conformation of HSA was also analyzed using synchronous fluorescence spectrometry.

  16. Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis

    Directory of Open Access Journals (Sweden)

    Thomas A. Milne

    2012-09-01

    Full Text Available Epigenetics is often defined as the study of heritable changes in gene expression or chromosome stability that don’t alter the underlying DNA sequence. Epigenetic changes are established through multiple mechanisms that include DNA methylation, non-coding RNAs and the covalent modification of specific residues on histone proteins. It is becoming clear not only that aberrant epigenetic changes are common in many human diseases such as leukemia, but that these changes by their very nature are malleable, and thus are amenable to treatment. Epigenetic based therapies have so far focused on the use of histone deacetylase (HDAC inhibitors and DNA methyltransferase inhibitors, which tend to have more general and widespread effects on gene regulation in the cell. However, if a unique molecular pathway can be identified, diseases caused by epigenetic mechanisms are excellent candidates for the development of more targeted therapies that focus on specific gene targets, individual binding domains, or specific enzymatic activities. Designing effective targeted therapies depends on a clear understanding of the role of epigenetic mutations during disease progression. The Mixed Lineage Leukemia (MLL protein is an example of a developmentally important protein that controls the epigenetic activation of gene targets in part by methylating histone 3 on lysine 4. MLL is required for normal development, but is also mutated in a subset of aggressive human leukemias and thus provides a useful model for studying the link between epigenetic cell memory and human disease. The most common MLL mutations are chromosome translocations that fuse the MLL gene in frame with partner genes creating novel fusion proteins. In this review, we summarize recent work that argues MLL fusion proteins could function through a single molecular pathway, but we also highlight important data that suggests instead that multiple independent mechanisms underlie MLL mediated leukemogenesis.

  17. Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Ballabio, Erica; Milne, Thomas A., E-mail: thomas.milne@imm.ox.ac.uk [MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital Headington, Oxford OX3 9DS (United Kingdom)

    2012-09-10

    Epigenetics is often defined as the study of heritable changes in gene expression or chromosome stability that don’t alter the underlying DNA sequence. Epigenetic changes are established through multiple mechanisms that include DNA methylation, non-coding RNAs and the covalent modification of specific residues on histone proteins. It is becoming clear not only that aberrant epigenetic changes are common in many human diseases such as leukemia, but that these changes by their very nature are malleable, and thus are amenable to treatment. Epigenetic based therapies have so far focused on the use of histone deacetylase (HDAC) inhibitors and DNA methyltransferase inhibitors, which tend to have more general and widespread effects on gene regulation in the cell. However, if a unique molecular pathway can be identified, diseases caused by epigenetic mechanisms are excellent candidates for the development of more targeted therapies that focus on specific gene targets, individual binding domains, or specific enzymatic activities. Designing effective targeted therapies depends on a clear understanding of the role of epigenetic mutations during disease progression. The Mixed Lineage Leukemia (MLL) protein is an example of a developmentally important protein that controls the epigenetic activation of gene targets in part by methylating histone 3 on lysine 4. MLL is required for normal development, but is also mutated in a subset of aggressive human leukemias and thus provides a useful model for studying the link between epigenetic cell memory and human disease. The most common MLL mutations are chromosome translocations that fuse the MLL gene in frame with partner genes creating novel fusion proteins. In this review, we summarize recent work that argues MLL fusion proteins could function through a single molecular pathway, but we also highlight important data that suggests instead that multiple independent mechanisms underlie MLL mediated leukemogenesis.

  18. Kinetic mechanism of the activation of human plasminogen by streptokinase.

    Science.gov (United States)

    Kosow, D P

    1975-10-07

    A method of determining the initial rate of plasminogen activation has been developed. The method has been used to investigate the mechanism of activation of human plasminogen by streptokinase. Plasmin formation follows saturation kinetics. Inhibition of plasmin formation by epsilon-aminocaproic acid is uncompetitive with a Ki of 0.6 mM. A model consistent with the data is that streptokinase induces a conformational change in the plasminogen molecule, producing an active center which cleaves an internal peptide bond to produce plasmin. Thus, streptokinase functions as a catalytic allosteric effector.

  19. Assessing neuromuscular mechanisms in human-exoskeleton interaction.

    Science.gov (United States)

    Sylla, N; Bonnet, V; Venture, G; Armande, N; Fraisse, P

    2014-01-01

    In this study, we propose to evaluate a 7 DOF exoskeleton in terms of motion control. Using criteria from the human motor control literature, inverse optimization was performed to assess an industrial screwing movement. The results of our study show that the hybrid composition of the free arm movement was accurately determined. At contrary, when wearing the exoskeleton, which produces an arbitrary determined torque compensation, the motion is different from the naturally adopted one. This study is part of the evaluation and comprehension of the complex neuromuscular mechanism resulting in wearing an exoskeleton several hours per day for industrial tasks assistance.

  20. Nanoscale Mechanical Stimulation of Human Mesenchymal Stem Cells

    Directory of Open Access Journals (Sweden)

    H Nikukar

    2014-05-01

    We observed significant responses after 1 and 2-week stimulations in cell number, cell shapes and phenotypical markers. Microarray was performed for all groups. Cell count showed normal cell growth with stimulation. However, cell surface area, cell perimeter, and arboration after 1-week stimulation showed significant increases. Immunofluorescent studies have showed significant increase in osteocalcin production after stimulation. Conclusions: Nanoscale mechanical vibration showed significant changes in human mesenchymal stem cell behaviours. Cell morphology changed to become more polygonal and increased expression of the osteoblast markers were noted. These findings with gene regulation changes suggesting nanoscale mechanostimulation has stimulated osteoblastogenesis.  Keywords:  Mesenchymal, Nanoscale, Stem Cells.

  1. Molecular mechanism of size control in development and human diseases

    Institute of Scientific and Technical Information of China (English)

    Xiaolong Yang; Tian Xu

    2011-01-01

    How multicellular organisms control their size is a fundamental question that fascinated generations of biologists.In the past 10 years, tremendous progress has been made toward our understanding of the molecular mechanism underlying size control. Original studies from Drosophila showed that in addition to extrinsic nutritional and hormonal cues, intrinsic mechanisms also play important roles in the control of organ size during development. Several novel signaling pathways such as insulin and Hippo-LATS signaling pathways have been identified that control organ size by regulating cell size and/or cell number through modulation of cell growth, cell division, and cell death. Later studies using mammalian cell and mouse models also demonstrated that the signaling pathways identified in flies are also conserved in mammals. Significantly, recent studies showed that dysregulation of size control plays important roles in the development of many human diseases sucha as cancer,diabetes,and hypertrophy.

  2. Mechanism of human antibody-mediated neutralization of Marburg virus.

    Science.gov (United States)

    Flyak, Andrew I; Ilinykh, Philipp A; Murin, Charles D; Garron, Tania; Shen, Xiaoli; Fusco, Marnie L; Hashiguchi, Takao; Bornholdt, Zachary A; Slaughter, James C; Sapparapu, Gopal; Klages, Curtis; Ksiazek, Thomas G; Ward, Andrew B; Saphire, Erica Ollmann; Bukreyev, Alexander; Crowe, James E

    2015-02-26

    The mechanisms by which neutralizing antibodies inhibit Marburg virus (MARV) are not known. We isolated a panel of neutralizing antibodies from a human MARV survivor that bind to MARV glycoprotein (GP) and compete for binding to a single major antigenic site. Remarkably, several of the antibodies also bind to Ebola virus (EBOV) GP. Single-particle EM structures of antibody-GP complexes reveal that all of the neutralizing antibodies bind to MARV GP at or near the predicted region of the receptor-binding site. The presence of the glycan cap or mucin-like domain blocks binding of neutralizing antibodies to EBOV GP, but not to MARV GP. The data suggest that MARV-neutralizing antibodies inhibit virus by binding to infectious virions at the exposed MARV receptor-binding site, revealing a mechanism of filovirus inhibition.

  3. Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti‐inflammatory effect

    National Research Council Canada - National Science Library

    Shen, Yuh‐Chiang; Chen, Chieh‐Fu; Chiou, Wen‐Fei

    2002-01-01

    .... To further elucidate the possible mechanism(s) underlying the ANDRO's effect, N ‐formyl‐methionyl‐leucyl‐phenylalanine (fMLP)‐induced adhesion and transmigration of isolated peripheral human neutrophils were studied...

  4. Mechanisms of GII.4 norovirus persistence in human populations.

    Directory of Open Access Journals (Sweden)

    Lisa C Lindesmith

    2008-02-01

    Full Text Available BACKGROUND: Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military, cruise ships, hospitals, and assisted living communities. The evolutionary mechanisms governing the persistence and emergence of new norovirus strains in human populations are unknown. Primarily organized by sequence homology into two major human genogroups defined by multiple genoclusters, the majority of norovirus outbreaks are caused by viruses from the GII.4 genocluster, which was first recognized as the major epidemic strain in the mid-1990s. Previous studies by our laboratory and others indicate that some noroviruses readily infect individuals who carry a gene encoding a functional alpha-1,2-fucosyltransferase (FUT2 and are designated "secretor-positive" to indicate that they express ABH histo-blood group antigens (HBGAs, a highly heterogeneous group of related carbohydrates on mucosal surfaces. Individuals with defects in the FUT2 gene are termed secretor-negative, do not express the appropriate HBGA necessary for docking, and are resistant to Norwalk infection. These data argue that FUT2 and other genes encoding enzymes that regulate processing of the HBGA carbohydrates function as susceptibility alleles. However, secretor-negative individuals can be infected with other norovirus strains, and reinfection with the GII.4 strains is common in human populations. In this article, we analyze molecular mechanisms governing GII.4 epidemiology, susceptibility, and persistence in human populations. METHODS AND FINDINGS: Phylogenetic analyses of the GII.4 capsid sequences suggested an epochal evolution over the last 20 y with periods of stasis followed by rapid evolution of novel epidemic strains. The epidemic strains show a linear relationship in time, whereby serial replacements emerge from the previous cluster. Five major evolutionary clusters were identified, and representative ORF2 capsid

  5. A experiência emocional atualizadora em Gestalt-terapia de curta duração

    OpenAIRE

    Ênio Brito Pinto

    2009-01-01

    Apresenta-se e se discute o conceito, de Alexander, de experiência emocional corretiva, sob a ótica da abordagem gestáltica. Propõe-se que em Gestalt-terapia se deva falar em experiência emocional atualizadora. Discute-se a noção de neurose e de psicopatologia em Gestalt-terapia, bem como as implicações desses conceitos no processo de Gestalt-terapia de Curta Duração.

  6. Bases filosóficas e implicações técnicas na Gestalt-terapia

    OpenAIRE

    Porto, Rosane Carneiro

    1989-01-01

    Este trabalho tem por objetivo fazer uma reflexão epistemológica das bases filosóficas da Gestalt-terapia, procurando relacioná-las com suas técnicas e procedimentos terapêuticos. A Gestalt-terapia é apresentada a partir de sua origem, incluindo-se uma biografia de Fritz Perls, onde fica evidenciada a influência de outras abordagens no seu pensamento. Os pressupostos filosóficos são enfocados procurando relacionar alguns conceitos centrais da fenomenologia e do existencialismo com a Gestalt-t...

  7. Bases filosóficas e implicações técnicas na Gestalt-terapia

    OpenAIRE

    Porto, Rosane Carneiro

    1989-01-01

    Este trabalho tem por objetivo fazer uma reflexão epistemológica das bases filosóficas da Gestalt-terapia, procurando relacioná-las com suas técnicas e procedimentos terapêuticos. A Gestalt-terapia é apresentada a partir de sua origem, incluindo-se uma biografia de Fritz Perls, onde fica evidenciada a influência de outras abordagens no seu pensamento. Os pressupostos filosóficos são enfocados procurando relacionar alguns conceitos centrais da fenomenologia e do existencialismo com a Gestalt-t...

  8. A experiência emocional atualizadora em Gestalt-terapia de curta duração

    Directory of Open Access Journals (Sweden)

    Ênio Brito Pinto

    2009-04-01

    Full Text Available Apresenta-se e se discute o conceito, de Alexander, de experiência emocional corretiva, sob a ótica da abordagem gestáltica. Propõe-se que em Gestalt-terapia se deva falar em experiência emocional atualizadora. Discute-se a noção de neurose e de psicopatologia em Gestalt-terapia, bem como as implicações desses conceitos no processo de Gestalt-terapia de Curta Duração.

  9. Detail and Gestalt Focus in Individuals with Optimal Outcomes from Autism Spectrum Disorders

    Science.gov (United States)

    Fitch, Allison; Fein, Deborah A.; Eigsti, Inge-Marie

    2015-01-01

    Individuals with high-functioning autism (HFA) have a cognitive style that privileges local over global or gestalt details. While not a core symptom of autism, individuals with HFA seem to reliably show this bias. Our lab has been studying a sample of children who have overcome their early ASD diagnoses, showing "optimal outcomes" (OO).…

  10. Gestalt and Figure-Ground: Reframing Graduate Attribute Conversations between Educational Developers and Academics

    Science.gov (United States)

    Knewstubb, Bernadette; Ruth, Alison

    2015-01-01

    Academics implementing graduate attributes, and the educational developers who support those academics, may experience graduate attributes and disciplinary knowledge and skills as unrelated dimensions of curriculum. Gestalt conceptions of curriculum, together with a figure-ground understanding of the relationship between disciplinary understanding…

  11. Gestalt Therapy: Student Perceptions of Fritz Perls in "Three Approaches to Psychotherapy"

    Science.gov (United States)

    Reilly, Joe; Jacobus, Veronica

    2009-01-01

    The "Three Approaches to Psychotherapy" ("TAP") videotape series introduces students to three major schools of psychotherapy: client-centered therapy, Gestalt therapy, and rational-emotive therapy. A sample of undergraduate students viewed the "TAP" series. The students were surveyed about their observations of…

  12. Reliability of the Advanced Psychodiagnostic Interpretation (API) Scoring System for the Bender Gestalt.

    Science.gov (United States)

    Aucone, Ernest J.; Raphael, Alan J.; Golden, Charles J.; Espe-Pfeifer, Patricia; Seldon, Jen; Pospisil, Tanya; Dornheim, Liane; Proctor-Weber, Zoe; Calabria, Michael

    1999-01-01

    Assessed the interrater reliability of the revised Advanced Psychodiagnostic Interpretation (API) (A. Raphael and C. Golden, 1998) scoring system for the Bender Gestalt Test (L. Bender, 1938). Agreement across nine raters exceeded 90% for each of three clinical protocols, and kappa statistics indicated good interrater reliability. (SLD)

  13. Multiple Sources of Test Bias on the WISC-R and Bender-Gestalt Test.

    Science.gov (United States)

    Oakland, Thomas; Feigenbaum, David

    1979-01-01

    Assessed test bias on the Wechsler Intelligence Test for Children-Revised (WISC-R) and Bender-Gestalt. On the Bender, evidence of bias was infrequent and irregular. On the WISC-R, group differences were most discernible for age, sex, family structure, and race. Consistent patterns of bias were not apparent among comparison groups. (Author)

  14. Comparison of the Minnesota Percepto-Diagnostic Test and Bender-Gestalt: Relationship with Achievement Criteria.

    Science.gov (United States)

    Fuller, Gerald B.; Wallbrown, Fred H.

    1983-01-01

    Compared the Bender Gestalt (BD) and Minnesota Percepto-Diagnostic Test (MPD) in predicting academic achievement for younger children (N=69). Results suggested that the MPD is more sensitive than the Bender in identifying visual-motor perception areas of achievement performance problems. (LLL)

  15. Correlations of the WRAT and PIAT Reading Recognition Subtest Scores with the VMI And Bender Gestalt.

    Science.gov (United States)

    Vance, Booney; Gore, William V.

    The relationship between word recognition subtests of the Wide Range Achievement Test and Peabody Individual Achievement Test with Bender-Gestalt and the Berry-Buktencia Test of Visual Motor Integration was examined with 27 children (7-14 years old) referred for psychological services. The Bender and Berry tests are among the most popular…

  16. Bender-Gestalt Emotional Indicators and Acting-Out Behavior in Young Children.

    Science.gov (United States)

    Trahan, Donald; Stricklin, Ann

    1979-01-01

    The relationship between 15 emotional indicators on the Bender Gestalt Test and the acting out behavior of 93 children, ages 5 to 12, as rated by their teachers, was investigated. Use of the Bender as a projective measure was seriously questioned. The ten-item behavioral rating scale is appended. (MH)

  17. Bender-Gestalt Test and Social Interactions of Kindergarten Children: Effects of Socialization Practices

    Science.gov (United States)

    Lifshitz, Michaela

    1978-01-01

    The present study assessed the extent to which kindergarten children's performance on the Bender-Gestalt Test is related to sex and sociocultural variables and to children's social behavior. Two distinctly different Israeli populations were included: the Druze and the Jews. Significant correlations between perceptual indicators and social…

  18. The Bender Visual Motor Gestalt Test: Implications for the Diagnosis and Prediction of Reading Achievement.

    Science.gov (United States)

    Lesiak, Judi

    1984-01-01

    Reviews 32 studies about the utility of the Bender Visual-Motor Gestalt Test (BG) as a predictor of reading, its relationship to reading achievement, and ability to differentiate between good and poor readers. Results question the use of the BG (scored using discrete error systems) in a diagnostic reading battery. (BH)

  19. Comparison of Two Scoring Systems for the Modified Version of the Bender-Gestalt Test.

    Science.gov (United States)

    Schachter, Steven; And Others

    1991-01-01

    Examined relative utility of two scoring systems for Modified Version of Bender-Gestalt Test in predicting performance on Developmental Test of Visual-Motor Integration. Findings from 53 kindergarten and 47 first grade students indicated that Qualitative Scoring System was significantly better predictor of visual-motor integration skills than…

  20. Comparison of the Bender-Gestalt and Revised Developmental Test of Visual-Motor Integration.

    Science.gov (United States)

    Armstrong, Barbara B.; Knopf, Karen F.

    1982-01-01

    Using children with learning disabilities and children enrolled in regular classrooms, test scores on the Bender-Gestalt and the Developmental Test of Visual-Motor Integration indicated high and significant correlations for the learning-disabled group and low but significant correlations for regular students. A nine-month mean difference in scores…

  1. Bender Gestalt Test Performance and the Word Recognition Skills of Disadvantaged Children

    Science.gov (United States)

    Baker, E. H.; Thurber, Steven

    1976-01-01

    The Bender Gestalt Test and the WRAT reading section were administered to 147 disadvantaged children. The zero-order correlation of -.62 was found to be moderated by the variable of age. For younger subjects, highly significant first- and second-order partial correlations were obtained with age and/or WISC information scores held constant. (Author)

  2. Further Validation of the Qualitative Scoring System for the Modified Bender-Gestalt Test.

    Science.gov (United States)

    Brannigan, Gary G.; And Others

    1995-01-01

    Compares the Qualitative Scoring System and the Developmental Scoring Systems, both Bender-Gestalt tests, in predicting achievement on the Metropolitan Achievement Test (MAT). In this study, first through fourth graders (n=409) from regular elementary schools were subjected to both tests; both systems correlated significantly with school…

  3. Correlations of the WRAT and PIAT Reading Recognition Subtest Scores with the VMI And Bender Gestalt.

    Science.gov (United States)

    Vance, Booney; Gore, William V.

    The relationship between word recognition subtests of the Wide Range Achievement Test and Peabody Individual Achievement Test with Bender-Gestalt and the Berry-Buktencia Test of Visual Motor Integration was examined with 27 children (7-14 years old) referred for psychological services. The Bender and Berry tests are among the most popular…

  4. Transactional Analysis and Gestalt Therapy Used in Conjunction with Group Counseling for Married Couples

    Science.gov (United States)

    Sisson, P. Joe; And Others

    1977-01-01

    This study investigated the effects of combining Transactional Analysis and Gestalt therapy with group counseling for married couples. Six treatment couples and 12 control group members were pre/post administered the Tennessee Self-Concept Scale to assess changes in the level of their self-esteem. There were some significant results. (Author/JEL)

  5. The Compatibility of Feminist Theology and Gestalt Therapy: A Study of "Practical-Values."

    Science.gov (United States)

    Hinksman, Barrie

    2001-01-01

    An on-going theoretical issue for pastoral counseling concerns the integration of psychological and theological concepts. The possibility of exploring the compatibility of Gestalt psychotherapy and feminist theology is considered with reference to the 'practical-values' of each, and it is proposed that there is significant common ground between…

  6. Gestalt Therapy with the Dying Patient: Integrative Work Using Clay, Poetry Therapy, and Creative Media.

    Science.gov (United States)

    Petzold, Hilarion G.

    1982-01-01

    Reports the use of death therapy with a cancer patient. Gestalt therapy and creative media were used to facilitate an integration of life and a sense of balance with life. Suggests that counseling the dying means walking along a stretch of the path together. (Author)

  7. Organization of Experience among Family Members in the Immediate Present: A Gestalt/Systems Integration.

    Science.gov (United States)

    Kaplan, Marvin L.; Kaplan, Netta R.

    1982-01-01

    Outlines two formulations that generate conceptual perspectives of immediate phenomena: (1) the family system has a time-enduring stability; (2) the family system has an immediate and temporary organization. Integrates systems thinking and Gestalt Therapy while recognizing individual experience as embedded in a self-maintaining system of the…

  8. Gestalt Therapy with Parents When a Child is Presented as the Problem.

    Science.gov (United States)

    Little, Linda F.

    1986-01-01

    Findings suggest that parents (N=23) who sought therapy because of "problematic" children differed in valuing style (e.g., rejection, extrinsic valuing, overprotection) from two samples of parents from normal populations. Parents who participated in Gestalt therapy groups made significant changes in their reported parenting styles. (Author/ABB)

  9. Gestalt Therapy in a Social Psychiatric Setting: The 'Oil & Water' Solution.

    Science.gov (United States)

    Neill, R. B.

    1979-01-01

    In this case study of a residential treatment center for emotionally disturbed adolescents, evaluative data demonstrated that Gestalt Therapy was neither designed nor intended for use in an institutional setting with severely disturbed young adolescents, with people of lower socioeconomic status or of low verbal skill and intelligence. (Author/SJL)

  10. Comparison of the Koppitz and Watkins Scoring Systems for the Bender Gestalt Test.

    Science.gov (United States)

    Johnston, Cris W.; Lanak, Brenda

    1985-01-01

    The Bender Gestalt Test was administered to 25 children (7-10 years old) referred for neuropsychological assessment and scored using the Koppitz system and the Watkins system. Although the scores obtained using the two different sets of criteria were highly correlated, the Watkins rules produced generally better performance. (Author/CL)

  11. Concurrent validity of the Koppitz Bender-Gestalt emotional indicators among women with mental retardation.

    Science.gov (United States)

    Dixon, J L

    1998-02-01

    This study evaluated the concurrent validity of Koppitz' revised Bender-Gestalt Emotional Indicators among 44 women with mental retardation. The concurrent validity of the Emotional Indicator total score was not supported when compared with responses on two widely used and accepted screening inventories, the Reiss Screen and the Inventory for Client and Agency Planning.

  12. Koppitz errors on the Bender-Gestalt for adult retardates: normative data.

    Science.gov (United States)

    Andert, J N; Dinning, W D; Hustak, T L

    1976-04-01

    Normative data on the Koppitz developmental scoring system for the Bender-Gestalt test were derived from a sample which included 510 protocols of adult resident retardates. Percentile norms are presented on Koppitz error scores for three AAMD ranges of retardation based on WAIS IQs and two AAMD ranges of retardation based on Stanford-Binet IQs.

  13. The Stability of Koppitz Scores on the Bender-Gestalt for Reading Disabled Children.

    Science.gov (United States)

    Wallbrown, Fred H.; Fremont, Theodore

    1980-01-01

    Findings support Koppitz's assertion that the total error score for the Bender Gestalt Test is stable and reliable. Working time is a relatively stable dimension of Bender performance, which may be of value in assessment activities. Perseveration and integration should not be used in differential diagnosis. (Author)

  14. The Koppitz Developmental Scoring System for the Bender-Gestalt: Is It Developmental?

    Science.gov (United States)

    Taylor, Ronald L.; And Others

    1984-01-01

    Investigated the developmental aspects of the Koppitz scoring system with 652 children who took the Bender Motor Gestalt Test. Scores were fitted to various developmental curves by computer. Results indicated only 35 percent of the Bender test performance variance was accounted for by age. (JAC)

  15. A Comparison of Special Education Teacher and Psychologist Scoring of the Bender Visual Motor Gestalt Test

    Science.gov (United States)

    Foster, Glen G.; And Others

    1976-01-01

    Ten special education teachers and two school psychologists scored the Bender-Gestalt protocals of elementary school children using the Koppitz scoring system. The reported correlations between teachers and school psychologists compared favorably to correlations between school psychologists as well as to interrater reliabilities reported in the…

  16. Emotional Indicators on the Bender-Gestalt and the Devereux Child Behavior Rating Scale

    Science.gov (United States)

    Gregory Mary K.

    1977-01-01

    A heterogeneous group of elementary school children referred for psycho-educational diagnosis were rated on the Devereux Child Behavior Rating Scale and the Bender Visual-Motor Gestalt Test, scoring for Koppitz Emotional Indicators. Findings suggests that certain DCB factors may be more predictive of emotional problems than others in the scale.…

  17. Understanding Phylogenies in Biology: The Influence of a Gestalt Perceptual Principle

    Science.gov (United States)

    Novick, Laura R.; Catley, Kefyn M.

    2007-01-01

    Cladograms, hierarchical diagrams depicting evolutionary histories among (groups of) species, are commonly drawn in 2 informationally equivalent formats--tree and ladder. The authors hypothesize that these formats are not computationally equivalent because the Gestalt principle of good continuation obscures the hierarchical structure of ladders.…

  18. Gestalt Processing in Autism: Failure to Process Perceptual Relationships and the Implications for Contextual Understanding

    Science.gov (United States)

    Brosnan, Mark J.; Scott, Fiona J.; Fox, Simone; Pye, Jackie

    2004-01-01

    Background: Deficits in autism have been characterised as a bias towards local over global processing. This paper examines whether there is a deficit in gestalt grouping in autism. Method: Twenty-five low-functioning children with autism and 25 controls who were matched for chronological age and verbal mental age took part in the study. Results:…

  19. Different Gestalt Processing for Different Actions? Comparing Object-Directed Reaching and Looking Time Measures

    Science.gov (United States)

    Vishton, P.M.; Ware, E.A.; Badger, A.N.

    2005-01-01

    Six experiments compared the Gestalt processing that mediates infant reaching and looking behaviors. Experiment 1 demonstrated that the positioning and timing of 8- and 9-month-olds' reaching was influenced by remembered relative motion. Experiment 2 suggested that a visible gap, without this relative motion, was not sufficient to produce these…

  20. Development of form similarity as a Gestalt grouping principle in infancy.

    Science.gov (United States)

    Quinn, Paul C; Bhatt, Ramesh S; Brush, Diana; Grimes, Autumn; Sharpnack, Heather

    2002-07-01

    Given evidence demonstrating that infants 3 months of age and younger can utilize the Gestalt principle of lightness similarity to group visually presented elements into organized percepts, four experiments using the familiarization/novelty-preference procedure were conducted to determine whether infants can also organize visual pattern information in accord with the Gestalt principle of form similarity. In Experiments 1 and 2, 6- to 7-month-olds, but not 3- to 4-month-olds, presented with generalization and discrimination tasks involving arrays of X and O elements responded as if they organized the elements into columns or rows based on form similarity. Experiments 3 and 4 demonstrated that the failure of the young infants to use form similarity was not due to insufficient processing time or the inability to discriminate between the individual X and O elements. The results suggest that different Gestalt principles may become functional over different time courses of development, and that not all principles are automatically deployed in the manner originally proposed by Gestalt theorists.

  1. The Use of Gestalt Interventions in the Treatment of the Resistant Alcohol-Dependent Client.

    Science.gov (United States)

    Ramey, Luellen

    1998-01-01

    Reviews ethical and practical dilemmas associated with clients who have hidden alcohol dependencies, and proposes an approach rooted in Gestalt counseling theory which confronts these issues and is compatible with a current emerging alcohol-treatment model. Suggests specific activities for addressing client resistance to revealing a hidden alcohol…

  2. Different Gestalt Processing for Different Actions? Comparing Object-Directed Reaching and Looking Time Measures

    Science.gov (United States)

    Vishton, P.M.; Ware, E.A.; Badger, A.N.

    2005-01-01

    Six experiments compared the Gestalt processing that mediates infant reaching and looking behaviors. Experiment 1 demonstrated that the positioning and timing of 8- and 9-month-olds' reaching was influenced by remembered relative motion. Experiment 2 suggested that a visible gap, without this relative motion, was not sufficient to produce these…

  3. Detail and Gestalt Focus in Individuals with Optimal Outcomes from Autism Spectrum Disorders

    Science.gov (United States)

    Fitch, Allison; Fein, Deborah A.; Eigsti, Inge-Marie

    2015-01-01

    Individuals with high-functioning autism (HFA) have a cognitive style that privileges local over global or gestalt details. While not a core symptom of autism, individuals with HFA seem to reliably show this bias. Our lab has been studying a sample of children who have overcome their early ASD diagnoses, showing "optimal outcomes" (OO).…

  4. Gestalt Therapy: Student Perceptions of Fritz Perls in "Three Approaches to Psychotherapy"

    Science.gov (United States)

    Reilly, Joe; Jacobus, Veronica

    2009-01-01

    The "Three Approaches to Psychotherapy" ("TAP") videotape series introduces students to three major schools of psychotherapy: client-centered therapy, Gestalt therapy, and rational-emotive therapy. A sample of undergraduate students viewed the "TAP" series. The students were surveyed about their observations of…

  5. Exploring the influence of gestalt therapy training on psychiatric nursing practice: stories from the field.

    Science.gov (United States)

    Kelly, Teresa; Howie, Linsey

    2011-08-01

    Psychiatric nurses interested in extending their interpersonal and psychotherapeutic skills sometimes undertake postgraduate training in gestalt therapy. Little is known about how this new knowledge and psychotherapeutic skill base informs their practice. This paper presents the findings of a qualitative study that aimed to explore the influence of gestalt therapy training on psychiatric nursing practice. Within a framework of narrative inquiry, four psychiatric nurses trained in gestalt therapy were invited to tell their stories of training in a gestalt approach to therapy, and recount their experiences of how it influenced their practice. In keeping with narrative analysis methods, the research findings were presented as a collection of four stories. Eight themes were derived from a thematic analysis conducted within and across the four stories. The discussion of the themes encapsulates the similarities and differences across the storied collection, providing a community and cultural context for understanding the individual stories. © 2011 The Authors. International Journal of Mental Health Nursing © 2011 Australian College of Mental Health Nurses Inc.

  6. Can two dots form a Gestalt? Measuring emergent features with the capacity coefficient.

    Science.gov (United States)

    Hawkins, Robert X D; Houpt, Joseph W; Eidels, Ami; Townsend, James T

    2016-09-01

    While there is widespread agreement among vision researchers on the importance of some local aspects of visual stimuli, such as hue and intensity, there is no general consensus on a full set of basic sources of information used in perceptual tasks or how they are processed. Gestalt theories place particular value on emergent features, which are based on the higher-order relationships among elements of a stimulus rather than local properties. Thus, arbitrating between different accounts of features is an important step in arbitrating between local and Gestalt theories of perception in general. In this paper, we present the capacity coefficient from Systems Factorial Technology (SFT) as a quantitative approach for formalizing and rigorously testing predictions made by local and Gestalt theories of features. As a simple, easily controlled domain for testing this approach, we focus on the local feature of location and the emergent features of Orientation and Proximity in a pair of dots. We introduce a redundant-target change detection task to compare our capacity measure on (1) trials where the configuration of the dots changed along with their location against (2) trials where the amount of local location change was exactly the same, but there was no change in the configuration. Our results, in conjunction with our modeling tools, favor the Gestalt account of emergent features. We conclude by suggesting several candidate information-processing models that incorporate emergent features, which follow from our approach. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Gestalt Processing in Autism: Failure to Process Perceptual Relationships and the Implications for Contextual Understanding

    Science.gov (United States)

    Brosnan, Mark J.; Scott, Fiona J.; Fox, Simone; Pye, Jackie

    2004-01-01

    Background: Deficits in autism have been characterised as a bias towards local over global processing. This paper examines whether there is a deficit in gestalt grouping in autism. Method: Twenty-five low-functioning children with autism and 25 controls who were matched for chronological age and verbal mental age took part in the study. Results:…

  8. Gestalt and Figure-Ground: Reframing Graduate Attribute Conversations between Educational Developers and Academics

    Science.gov (United States)

    Knewstubb, Bernadette; Ruth, Alison

    2015-01-01

    Academics implementing graduate attributes, and the educational developers who support those academics, may experience graduate attributes and disciplinary knowledge and skills as unrelated dimensions of curriculum. Gestalt conceptions of curriculum, together with a figure-ground understanding of the relationship between disciplinary understanding…

  9. Understanding Phylogenies in Biology: The Influence of a Gestalt Perceptual Principle

    Science.gov (United States)

    Novick, Laura R.; Catley, Kefyn M.

    2007-01-01

    Cladograms, hierarchical diagrams depicting evolutionary histories among (groups of) species, are commonly drawn in 2 informationally equivalent formats--tree and ladder. The authors hypothesize that these formats are not computationally equivalent because the Gestalt principle of good continuation obscures the hierarchical structure of ladders.…

  10. Human adipocyte function is impacted by mechanical cues.

    Science.gov (United States)

    Pellegrinelli, V; Heuvingh, J; du Roure, O; Rouault, C; Devulder, A; Klein, C; Lacasa, M; Clément, E; Lacasa, D; Clément, K

    2014-06-01

    Fibrosis is a hallmark of human white adipose tissue (WAT) during obesity-induced chronic inflammation. The functional impact of increased interstitial fibrosis (peri-adipocyte fibrosis) on adjacent adipocytes remains unknown. Here we developed a novel in vitro 3D culture system in which human adipocytes and decellularized material of adipose tissue (dMAT) from obese subjects are embedded in a peptide hydrogel. When cultured with dMAT, adipocytes showed decreased lipolysis and adipokine secretion and increased expression/production of cytokines (IL-6, G-CSF) and fibrotic mediators (LOXL2 and the matricellular proteins THSB2 and CTGF). Moreover, some alterations including lipolytic activity and fibro-inflammation also occurred when the adipocyte/hydrogel culture was mechanically compressed. Notably, CTGF expression levels correlated with the amount of peri-adipocyte fibrosis in WAT from obese individuals. Moreover, dMAT-dependent CTGF promoter activity, which depends on β1-integrin/cytoskeleton pathways, was enhanced in the presence of YAP, a mechanosensitive co-activator of TEAD transcription factors. Mutation of TEAD binding sites abolished the dMAT-induced promoter activity. In conclusion, fibrosis may negatively affect human adipocyte function via mechanosensitive molecules, in part stimulated by cell deformation. Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

  11. Summary of Human Ankle Mechanical Impedance During Walking

    Science.gov (United States)

    Rouse, Elliott J.; Krebs, Hermano Igo

    2016-01-01

    The human ankle joint plays a critical role during walking and understanding the biomechanical factors that govern ankle behavior and provides fundamental insight into normal and pathologically altered gait. Previous researchers have comprehensively studied ankle joint kinetics and kinematics during many biomechanical tasks, including locomotion; however, only recently have researchers been able to quantify how the mechanical impedance of the ankle varies during walking. The mechanical impedance describes the dynamic relationship between the joint position and the joint torque during perturbation, and is often represented in terms of stiffness, damping, and inertia. The purpose of this short communication is to unify the results of the first two studies measuring ankle mechanical impedance in the sagittal plane during walking, where each study investigated differing regions of the gait cycle. Rouse et al. measured ankle impedance from late loading response to terminal stance, where Lee et al. quantified ankle impedance from pre-swing to early loading response. While stiffness component of impedance increases significantly as the stance phase of walking progressed, the change in damping during the gait cycle is much less than the changes observed in stiffness. In addition, both stiffness and damping remained low during the swing phase of walking. Future work will focus on quantifying impedance during the “push off” region of stance phase, as well as measurement of these properties in the coronal plane. PMID:27766187

  12. Calendula extract: effects on mechanical parameters of human skin.

    Science.gov (United States)

    Akhtar, Naveed; Zaman, Shahiq Uz; Khan, Barkat Ali; Amir, Muhammad Naeem; Ebrahimzadeh, Muhammad Ali

    2011-01-01

    The aim of this study was to evaluate the effects of newly formulated topical cream of Calendula officinalis extract on the mechanical parameters of the skin by using the cutometer. The Cutometer 580 MPA is a device that is designed to measure the mechanical properties of the skin in response to the application of negative pressure. This non-invasive method can be useful for objective and quantitative investigation of age related changes in skin, skin elasticity, skin fatigue, skin hydration, and evaluation of the effects of cosmetic and antiaging topical products. Two creams (base and formulation) were prepared for the study. Both the creams were applied to the cheeks of 21 healthy human volunteers for a period of eight weeks. Every individual was asked to come on week 1, 2, 3, 4, 5, 6, 7, and 8 and measurements were taken by using Cutometer MPA 580 every week. Different mechanical parameters of the skin measured by the cutometer were; R0, R1, R2, R5, R6, R7, and R8. These were then evaluated statistically to measure the effects produced by these creams. Using ANOVA, and t-test it was found that R0, and R6 were significant (p 0.05). The instrumental measurements produced by formulation reflected significant improvements in hydration and firmness of skin.

  13. Mechanical compression attenuates normal human bronchial epithelial wound healing

    Directory of Open Access Journals (Sweden)

    Malavia Nikita

    2009-02-01

    Full Text Available Abstract Background Airway narrowing associated with chronic asthma results in the transmission of injurious compressive forces to the bronchial epithelium and promotes the release of pro-inflammatory mediators and the denudation of the bronchial epithelium. While the individual effects of compression or denudation are well characterized, there is no data to elucidate how these cells respond to the application of mechanical compression in the presence of a compromised epithelial layer. Methods Accordingly, differentiated normal human bronchial epithelial cells were exposed to one of four conditions: 1 unperturbed control cells, 2 single scrape wound only, 3 static compression (6 hours of 30 cmH2O, and 4 6 hours of static compression after a scrape wound. Following treatment, wound closure rate was recorded, media was assayed for mediator content and the cytoskeletal network was fluorescently labeled. Results We found that mechanical compression and scrape injury increase TGF-β2 and endothelin-1 secretion, while EGF content in the media is attenuated with both injury modes. The application of compression after a pre-existing scrape wound augmented these observations, and also decreased PGE2 media content. Compression stimulated depolymerization of the actin cytoskeleton and significantly attenuated wound healing. Closure rate was partially restored with the addition of exogenous PGE2, but not EGF. Conclusion Our results suggest that mechanical compression reduces the capacity of the bronchial epithelium to close wounds, and is, in part, mediated by PGE2 and a compromised cytoskeleton.

  14. Selection and inhibition mechanisms for human voluntary action decisions.

    Science.gov (United States)

    Zhang, Jiaxiang; Hughes, Laura E; Rowe, James B

    2012-10-15

    One can choose between action alternatives that have no apparent difference in their outcomes. Such voluntary action decisions are associated with widespread frontal-parietal activation, and a tendency to inhibit the repetition of a previous action. However, the mechanism of initiating voluntary actions and the functions of different brain regions during this process remains largely unknown. Here, we combine computational modeling and functional magnetic resonance imaging to test the selection and inhibition mechanisms that mediate trial-to-trial voluntary action decisions. We fitted an optimized accumulator model to behavioral responses in a finger-tapping task in which participants were instructed to make chosen actions or specified actions. Model parameters derived from each individual were then applied to estimate the expected accumulated metabolic activity (EAA) engaged in every single trial. The EAA was associated with blood oxygenation level-dependent responses in a decision work that was maximal in the supplementary motor area and the caudal anterior cingulate cortex, consistent with a competitive accumulation-to-threshold mechanism for action decision by these regions. Furthermore, specific inhibition of the previous action's accumulator was related to the suppression of response repetition. This action-specific inhibition correlated with the activity of the right inferior frontal gyrus, when the option to repeat existed. Our findings suggest that human voluntary action decisions are mediated by complementary processes of intentional selection and inhibition.

  15. Development of gestalt-reading processes in children: assessment using the Boder test.

    Science.gov (United States)

    Chiarenza, G A; Coati, P; Cucci, M

    1994-01-01

    According to Boder, there are two processes involved in reading: visual-gestalt and analytic-phonetic. The gestalt process is activated for known words, forming part of the child's "sight vocabulary", and it enables him/her to recognize words even when they are exposed for a very short time. The analytic-phonetic process involves the auditory channel when the words are not part of the "sight vocabulary" and require a spelling process. At first, neither the English version nor the Italian adaptation of the Boder test included a control of word exposition time (ET) and reading time (RT). Both parameters are necessary for a check of the gestalt and phonetic processes. The aim of this paper was the assessment of minimum ET for the words belonging to the "sight vocabulary" and of RT for a word read through a gestalt process. Seventy-five primary schoolchildren from the first to the fifth class were presented with 100 meaningful words (MF) and 100 meaningless (ML) words, using ETs ranging from 150 to 650 ms. The results showed that, at the age of 7 years, the gestalt process was completely developed. Of MF words, 95% were correctly read and it did not change significantly with longer ETs. The RT for MF words did not change with different ETs and remained stable after the age of 7 years. Finally, the RT for ML words was always longer than the RT for MF words, and the difference was significant in 8-, 9- and 10-year-old children.

  16. Gestalt assessment of online educational resources may not be sufficiently reliable and consistent.

    Science.gov (United States)

    Krishnan, Keeth; Thoma, Brent; Trueger, N Seth; Lin, Michelle; Chan, Teresa M

    2017-04-01

    Online open educational resources are increasingly used in medical education, particularly blogs and podcasts. However, it is unclear whether these resources can be adequately appraised by end-users. Our goal was to determine whether gestalt-based recommendations are sufficient for emergency medicine trainees and attending physicians to reliably recommend online educational resources to others. Raters (33 trainees and 21 attendings in emergency medicine from North America) were asked to rate 40 blog posts according to whether, based on their gestalt, they would recommend the resource to (1) a trainee or (2) an attending physician. The ratings' reliability was assessed using intraclass correlation coefficients (ICC). Associations between groups' mean scores were assessed using Pearson's r. A repeated measures analysis of variance (RM-ANOVA) was completed to determine the effect of the level of training on gestalt recommendation scale (i. e. trainee vs. attending). Trainees demonstrated poor reliability when recommending resources for other trainees (ICC = 0.21, 95% CI 0.13-0.39) and attendings (ICC = 0.16, 95% CI = 0.09-0.30). Similarly, attendings had poor reliability when recommending resources for trainees (ICC = 0.27, 95% CI 0.18-0.41) and other attendings (ICC = 0.22, 95% CI 0.14-0.35). There were moderate correlations between the mean scores for each blog post when either trainees or attendings considered the same target audience. The RM-ANOVA also corroborated that there is a main effect of the proposed target audience on the ratings by both trainees and attendings. A gestalt-based rating system is not sufficiently reliable when recommending online educational resources to trainees and attendings. Trainees' gestalt ratings for recommending resources for both groups were especially unreliable. Our findings suggest the need for structured rating systems to rate online educational resources.

  17. Applying analysis of the gestalt theory in the digital image processing%格式塔理论在数字图像处理中的应用

    Institute of Scientific and Technical Information of China (English)

    程焱辉; 张立; 王必安

    2012-01-01

    With the gestaltt theory and the digital image processing technology,the article analyses the application of the digital image processing with some of the interrelated conclusion of the gestalt visual psychology, advances the method of the digital image fragmenting and the digital image rebuild based on the gestalt visual psychology, strives to reach the consistence of the objective image algorthm and the subjective experience of the human, probes into the subjective method of the digital image quality estimating.%结合格式塔心理学理论与数字图像处理技术,分析了格式塔视觉心理的相关结论在图像处理方面的一些应用,提出了基于格式塔视觉心理的图像分割和图像重建方法,力求达到图像客观算法与人的主观感受的一致性,探讨图像质量评价的主观方法.

  18. Mechanisms of human immunodeficiency virus type 2 RNA packaging

    DEFF Research Database (Denmark)

    Ni, Na; Nikolaitchik, Olga A; Dilley, Kari A;

    2011-01-01

    that specifically recognize stem-loop motifs in the viral genomes, an assay termed single virion analysis. These studies revealed that >90% of the HIV-2 particles contained viral RNAs and that RNAs derived from different viruses were copackaged frequently. Furthermore, the frequencies of heterozygous particles...... two monomeric RNAs. Additionally, single virion analyses demonstrated a similar RNA distribution in viral particles regardless of whether both viruses had a functional gag or one of the viruses had a nonfunctional gag, providing further support for the trans-packaging hypothesis. Together......Human immunodeficiency virus type 2 (HIV-2) has been reported to have a distinct RNA packaging mechanism, referred to as cis packaging, in which Gag proteins package the RNA from which they were translated. We examined the progeny generated from dually infected cell lines that contain two HIV-2...

  19. Mechanical impedance of the human body in vertical direction.

    Science.gov (United States)

    Holmlund, P; Lundström, R; Lindberg, L

    2000-08-01

    The mechanical impedance of the human body in sitting posture and vertical direction was measured during different experimental conditions, such as vibration level (0.5-1.4 m/s2), frequency (2-100 Hz), body weight (57-92 kg), relaxed and erect upper body posture. The outcome shows that impedance increases with frequency up to a peak at about 5 Hz after which it decreases in a complex manner which includes two additional peaks. The frequency at which the first and second impedance peak occurs decreases with higher vibration level. Erect, compared with relaxed body posture resulted in higher impedance magnitudes and with peaks located at somewhat higher frequencies. Heavy persons show higher impedance magnitudes and peaks at lower frequencies.

  20. Mechanics of airflow in the human nasal airways.

    Science.gov (United States)

    Doorly, D J; Taylor, D J; Schroter, R C

    2008-11-30

    The mechanics of airflow in the human nasal airways is reviewed, drawing on the findings of experimental and computational model studies. Modelling inevitably requires simplifications and assumptions, particularly given the complexity of the nasal airways. The processes entailed in modelling the nasal airways (from defining the model, to its production and, finally, validating the results) is critically examined, both for physical models and for computational simulations. Uncertainty still surrounds the appropriateness of the various assumptions made in modelling, particularly with regard to the nature of flow. New results are presented in which high-speed particle image velocimetry (PIV) and direct numerical simulation are applied to investigate the development of flow instability in the nasal cavity. These illustrate some of the improved capabilities afforded by technological developments for future model studies. The need for further improvements in characterising airway geometry and flow together with promising new methods are briefly discussed.

  1. Molecular mechanisms of acrolein toxicity: relevance to human disease.

    Science.gov (United States)

    Moghe, Akshata; Ghare, Smita; Lamoreau, Bryan; Mohammad, Mohammad; Barve, Shirish; McClain, Craig; Joshi-Barve, Swati

    2015-02-01

    Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant and its potential as a serious environmental health threat is beginning to be recognized. Humans are exposed to acrolein per oral (food and water), respiratory (cigarette smoke, automobile exhaust, and biocide use) and dermal routes, in addition to endogenous generation (metabolism and lipid peroxidation). Acrolein has been suggested to play a role in several disease states including spinal cord injury, multiple sclerosis, Alzheimer's disease, cardiovascular disease, diabetes mellitus, and neuro-, hepato-, and nephro-toxicity. On the cellular level, acrolein exposure has diverse toxic effects, including DNA and protein adduction, oxidative stress, mitochondrial disruption, membrane damage, endoplasmic reticulum stress, and immune dysfunction. This review addresses our current understanding of each pathogenic mechanism of acrolein toxicity, with emphasis on the known and anticipated contribution to clinical disease, and potential therapies.

  2. Perception of global gestalt by temporal integration in simultanagnosia.

    Science.gov (United States)

    Huberle, Elisabeth; Rupek, Paul; Lappe, Markus; Karnath, Hans-Otto

    2009-01-01

    Patients with bilateral parieto-occipital brain damage may show intact processing of individual objects, while their perception of multiple objects is disturbed at the same time. The deficit is termed 'simultanagnosia' and has been discussed in the context of restricted visual working memory and impaired visuo-spatial attention. Recent observations indicated that the recognition of global shapes can be modulated by the spatial distance between individual objects in patients with simultanagnosia and thus is not an all-or-nothing phenomenon depending on spatial continuity. However, grouping mechanisms not only require the spatial integration of visual information, but also involve integration processes over time. The present study investigated motion-defined integration mechanisms in two patients with simultanagnosia. We applied hierarchical organized stimuli of global objects that consisted of coherently moving dots ('shape-from-motion'). In addition, we tested the patients' ability to recognize biological motion by presenting characteristic human movements ('point-light-walker'). The data revealed largely preserved perception of biological motion, while the perception of motion-defined shapes was impaired. Our findings suggest separate mechanisms underlying the recognition of biological motion and shapes defined by coherently moving dots. They thus argue against a restriction in the overall capacity of visual working memory over time as a general explanation for the impaired global shape recognition in patients with simultanagnosia.

  3. Apoptosis mechanisms of human gastric cancer cell line MKN-45 infected with human mutant p27

    Institute of Scientific and Technical Information of China (English)

    Jin-Shui Zhu; Long Wang; Guo-Qiang Cheng; Qin Li; Zu-Ming Zhu; Li Zhu

    2005-01-01

    AIM: To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS: The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment analysis, we measured the apoptotic effect of Ad-p27mt on the human gastric cancer cells. RESULTS: Ad-p27mt was successfully constructed and the infection efficiency reached 100%. After 18 h of infection, we observed an apoptotic hypodiploid peak on the flow cytometer before G1-S and apoptotic characteristic bands in the DNA electrophoresis. The apoptotic rate detected by TUNEL method was significantly higher in the Ad-p27mt group (89.4±3.12%)compared to the control group (3.12±0.13%, P < 0.01).CONCLUSION: Human mutant p27 can induce apoptosis of the human gastric cancer cells in vitro.

  4. Koppitz Bender Gestalt Scores in First-Grade Children as Related to Ethnocultural Background, Socioeconomic Class, and Sex Factors

    Science.gov (United States)

    Zuelzer, Margot B.; And Others

    1976-01-01

    This study investigated whether Koppitz Bender Gestalt Scores were related to ethnocultural, socioeconomic and sex factors when statistical controls for intelligence were used. When intelligence was controlled for, it eliminated many effects for these variables. Results are discussed. (NG)

  5. Natural Defense Mechanisms of the Human Brain against Chronic Ischemia

    Directory of Open Access Journals (Sweden)

    A. V. Sergeev

    2015-01-01

    Full Text Available Objective: to study the structural bases of natural defense mechanisms of the human brain against chronic ischemia. Materials and methods. To accomplish this, histological, immunohistochemical (NSE, calbindin, NPY, p38 and morphometric examinations of intraoperative biopsy specimens were performed to determine the reorganization of excitatory and inhibitory neurons in the ischemic penumbra of the temporal cerebral cortex (CC. Morphometric analysis was made using the specially developed algorithms to verify neurons and their elements in the ImageJ 1.46 program. Results. The reduction in the total numerical density of neurons and synapses in chronic ischemia was ascertained to be accompanied by the compensatorily enhanced expression of NSE, calbindin, p38, and NPY in the remaining CC neurons. There were signs of hypertrophy of inhibitory CC interneurons and growth of their processes. In consequence, the impact of inhibitory CC interneurons on excitatory neurons was likely to enhance. Conclusion. In chronic ischemia, the human brain is anticipated to respond to damage to some cells via compensatory excitatory and inhibitory neuronal reorganization directed towards its natural defense against excitatory damage and towards better conditions for compensatory recovery of the structure and function of CC. 

  6. A mechanism for frequency modulation in songbirds shared with humans.

    Science.gov (United States)

    Amador, Ana; Margoliash, Daniel

    2013-07-03

    In most animals that vocalize, control of fundamental frequency is a key element for effective communication. In humans, subglottal pressure controls vocal intensity but also influences fundamental frequency during phonation. Given the underlying similarities in the biomechanical mechanisms of vocalization in humans and songbirds, songbirds offer an attractive opportunity to study frequency modulation by pressure. Here, we present a novel technique for dynamic control of subsyringeal pressure in zebra finches. By regulating the opening of a custom-built fast valve connected to the air sac system, we achieved partial or total silencing of specific syllables, and could modify syllabic acoustics through more complex manipulations of air sac pressure. We also observed that more nuanced pressure variations over a limited interval during production of a syllable concomitantly affected the frequency of that syllable segment. These results can be explained in terms of a mathematical model for phonation that incorporates a nonlinear description for the vocal source capable of generating the observed frequency modulations induced by pressure variations. We conclude that the observed interaction between pressure and frequency was a feature of the source, not a result of feedback control. Our results indicate that, beyond regulating phonation or its absence, regulation of pressure is important for control of fundamental frequencies of vocalizations. Thus, although there are separate brainstem pathways for syringeal and respiratory control of song production, both can affect airflow and frequency. We hypothesize that the control of pressure and frequency is combined holistically at higher levels of the vocalization pathways.

  7. Neural mechanisms of discourse comprehension: a human lesion study.

    Science.gov (United States)

    Barbey, Aron K; Colom, Roberto; Grafman, Jordan

    2014-01-01

    Discourse comprehension is a hallmark of human social behaviour and refers to the act of interpreting a written or spoken message by constructing mental representations that integrate incoming language with prior knowledge and experience. Here, we report a human lesion study (n = 145) that investigates the neural mechanisms underlying discourse comprehension (measured by the Discourse Comprehension Test) and systematically examine its relation to a broad range of psychological factors, including psychometric intelligence (measured by the Wechsler Adult Intelligence Scale), emotional intelligence (measured by the Mayer, Salovey, Caruso Emotional Intelligence Test), and personality traits (measured by the Neuroticism-Extraversion-Openness Personality Inventory). Scores obtained from these factors were submitted to voxel-based lesion-symptom mapping to elucidate their neural substrates. Stepwise regression analyses revealed that working memory and extraversion reliably predict individual differences in discourse comprehension: higher working memory scores and lower extraversion levels predict better discourse comprehension performance. Lesion mapping results indicated that these convergent variables depend on a shared network of frontal and parietal regions, including white matter association tracts that bind these areas into a coordinated system. The observed findings motivate an integrative framework for understanding the neural foundations of discourse comprehension, suggesting that core elements of discourse processing emerge from a distributed network of brain regions that support specific competencies for executive and social function.

  8. Differences in Mechanical Properties of the Human and Monkey Tibia

    Science.gov (United States)

    Arnaud, Sara B.; Hutchinson, T. M.; Bakulin, A. V.; Rahkmanov, A. S.; Steele, C. R.; Hargens, Alan R. (Technical Monitor)

    1996-01-01

    A method which uses an instrument that detects the response of a long bone to a vibratory stimulus to quantify mechanical properties non-invasively was revised and validated for use in the tibia. Stored data from healthy men was reanalyzed and compared with values from non-human primates. The analysis uses the relationship K(sub b) = 48 EI/L(sup 3) where K(sub b) is the lateral stiffness of a beam with force applied midspan, E is the elastic modulus, I the geometric moment of inertia and L, the limb length. Values for stiffness (EI, Nm(sup2)), the Euler buckling load (P(sub cr) = EI (pi/L)(sup 2)), and bone sufficiency (S) which represents the axial load the bone can support, adjusted to BW (S=P(sub cr)/BW) were obtained. The interest precision of the method in relaxed men, 5.8%, and in sedated male monkeys, 4.3%, was based on repeated measures in the same subjects at 1 month intervals. The R tibias of 40 men, aged 38.6 +/- 7.3 yrs with BW 78.9 +/- 7.9 kg, showed average (+/- SD) L to be 35 +/- 2 cm, EI 222 +/- 71 Nm(sup 2), P(sub cr) 18.1 +/- 4.9 kN, and S 23.4 +/- 5.7 N. The R tibias of 24 Rhesus monkeys ranging in age from 2-12 years, BW 4.9 +/- 3 kg, showed L to be 14.7 +/- 1.9 cm, EI 6.0 +/- 4.8 Nm(sup 2), P(sub cr) 2.51 +/- 1.2 kN and S 57.3 N. These measurements indicate that the tibia of a terrestrial non-human primate, M. mulatta, has higher load carrying capacity for the level of body weights in the species than the human bone.

  9. The possible mechanisms of the human microbiome in allergic diseases.

    Science.gov (United States)

    Ipci, Kagan; Altıntoprak, Niyazi; Muluk, Nuray Bayar; Senturk, Mehmet; Cingi, Cemal

    2017-02-01

    In the present paper, we discuss the importance of the microbiome in allergic disease. In this review paper, the data from the Medline (PubMed) and search engine of Kirikkale University were systematically searched for all relevant articles in June 15th, 2015 for the past 30 years. The keywords of "microbiome", "dysbiosis", "allergy", "allergic rhinitis", "allergic disease", "mechanisms" and "treatment" were used alone or together. In this paper, microbiomes were presented in terms of "Definition", "Influence of \\the human microbiome on health", "The microbiome and allergic diseases", and "Modulation of the gut microbiota in terms of treatment and prevention". Microbiological dysbiosis is also reviewed. The microbiome is the genetic material of all microbes (bacteria, fungi, protozoa, and viruses) that live on or in the human body. Microbes outnumber human cells in a 10:1 ratio. Most microbes live in the gut, particularly the large intestine. Changes in the immune function of the respiratory tract are (at least in theory) linked to the immunomodulatory activity of the gut microbiota via the concept of a "common mucosal response". The gut microbiota shapes systemic immunity, thus affecting the lung mucosa. Alternatively, changes in the gut microbiota may reflect alterations in the oropharyngeal microbiota, which may in turn directly affect the lung microbiota and host immune responses via microaspiration. Dysbiosis is defined as qualitative and quantitative changes in the intestinal flora; and modern diet and lifestyle, antibiotics, psychological and physical stress result in alterations in bacterial metabolism, as well as the overgrowth of potentially pathogenic microorganisms. All immune system components are directly or indirectly regulated by the microbiota. The nature of microbial exposure early in life appears to be important for the development of robust immune regulation; disruption of either the microbiota or the host response can trigger chronic

  10. Hibernation Control Mechanism and Possible Applications to Humans

    Science.gov (United States)

    Kondo, N.

    Mammalian hibernation, characterized by the ability to survive temporarily at low body temperatures close to 0oC, has been reported to increase resistance to various lethal events such as low body temperature, severe ischemia, bacterial infection and irradiation, and to prolong the life span. The application of this physiological phenomenon to space life has been dreamed of. However, realization of this dream has been prevented by a poor understanding of the control mechanisms of hibernation. Recent findings of a novel and unique protein complex (HP) in the blood of chipmunks, a rodent hibernator, which is controlled by the endogenous circannual rhythm of hibernation, allowed new developments in understanding the molecular mechanism of hibernation and its physiological significance. From these studies, two hormones regulated by the brain were identified as promising candidate molecules controlling HP production in the liver, assuming that hibernation is controlled via the neuroendocrine system and regulated by the endogenous circannual rhythm in the brain. A circannual HP rhythm was observed in chipmunks maintaining euthermia under conditions of constant warmth, suggesting that the physiological control of hibernation progresses without a lowering of body temperature. Furthermore, the study of HP rhythm on longevity revealed that a circannual rhythm plays an essential role in the much longer life span of hibernators. The present progress in hibernation research may open a new pathway for manipulating a circannual rhythm controlling hibernation in humans. In the future, this will make it feasible to take advantage of hibernation in space life.

  11. Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs

    NARCIS (Netherlands)

    Kim, T.J.; Joo, C.; Seong, J.; Vafabakhsh, R.; Botvinick, E.L.; Berns, M.W.; Palmer, A.E.; Wang, N.; Ha, T.; Jakobsson, E.; Sun, J.; Wang, Y.

    2015-01-01

    It is unclear that how subcellular organelles respond to external mechanical stimuli. Here, we investigated the molecular mechanisms by which mechanical force regulates Ca2+ signaling at endoplasmic reticulum (ER) in human mesenchymal stem cells. Without extracellular Ca2+, ER Ca2+ release is the so

  12. Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs

    NARCIS (Netherlands)

    Kim, T.J.; Joo, C.; Seong, J.; Vafabakhsh, R.; Botvinick, E.L.; Berns, M.W.; Palmer, A.E.; Wang, N.; Ha, T.; Jakobsson, E.; Sun, J.; Wang, Y.

    2015-01-01

    It is unclear that how subcellular organelles respond to external mechanical stimuli. Here, we investigated the molecular mechanisms by which mechanical force regulates Ca2+ signaling at endoplasmic reticulum (ER) in human mesenchymal stem cells. Without extracellular Ca2+, ER Ca2+ release is the

  13. Soft tissues store and return mechanical energy in human running.

    Science.gov (United States)

    Riddick, R C; Kuo, A D

    2016-02-08

    During human running, softer parts of the body may deform under load and dissipate mechanical energy. Although tissues such as the heel pad have been characterized individually, the aggregate work performed by all soft tissues during running is unknown. We therefore estimated the work performed by soft tissues (N=8 healthy adults) at running speeds ranging 2-5 m s(-1), computed as the difference between joint work performed on rigid segments, and whole-body estimates of work performed on the (non-rigid) body center of mass (COM) and peripheral to the COM. Soft tissues performed aggregate negative work, with magnitude increasing linearly with speed. The amount was about -19 J per stance phase at a nominal 3 m s(-1), accounting for more than 25% of stance phase negative work performed by the entire body. Fluctuations in soft tissue mechanical power over time resembled a damped oscillation starting at ground contact, with peak negative power comparable to that for the knee joint (about -500 W). Even the positive work from soft tissue rebound was significant, about 13 J per stance phase (about 17% of the positive work of the entire body). Assuming that the net dissipative work is offset by an equal amount of active, positive muscle work performed at 25% efficiency, soft tissue dissipation could account for about 29% of the net metabolic expenditure for running at 5 m s(-1). During running, soft tissue deformations dissipate mechanical energy that must be offset by active muscle work at non-negligible metabolic cost.

  14. A comparison of clinical and nonclinical groups of children on the bender - gestalt and draw a person tests

    OpenAIRE

    Özer, Serap

    2010-01-01

    The present study compared a clinical and a control sample of Turkish children on the Bender Gestalt and Draw A Person tests. 44 of the children from a clinic sample were compared to 44 children from a matched nonclinical school sample The tests were scored according to the Koppitz criteria. ANOVA comparisons showed differences on the Bender Gestalt test, and the HFD. The two groups did not differ on the number of Emotional Indicators. Correct classification of the children in the clinical gr...

  15. Individual Gestalt Is Unreliable for the Evaluation of Quality in Medical Education Blogs: A METRIQ Study.

    Science.gov (United States)

    Thoma, Brent; Sebok-Syer, Stefanie S; Krishnan, Keeth; Siemens, Marshall; Trueger, N Seth; Colmers-Gray, Isabelle; Woods, Rob; Petrusa, Emil; Chan, Teresa

    2017-09-01

    Open educational resources such as blogs are increasingly used for medical education. Gestalt is generally the evaluation method used for these resources; however, little information has been published on it. We aim to evaluate the reliability of gestalt in the assessment of emergency medicine blogs. We identified 60 English-language emergency medicine Web sites that posted clinically oriented blogs between January 1, 2016, and February 24, 2016. Ten Web sites were selected with a random-number generator. Medical students, emergency medicine residents, and emergency medicine attending physicians evaluated the 2 most recent clinical blog posts from each site for quality, using a 7-point Likert scale. The mean gestalt scores of each blog post were compared between groups with Pearson's correlations. Single and average measure intraclass correlation coefficients were calculated within groups. A generalizability study evaluated variance within gestalt and a decision study calculated the number of raters required to reliably (>0.8) estimate quality. One hundred twenty-one medical students, 88 residents, and 100 attending physicians (93.6% of enrolled participants) evaluated all 20 blog posts. Single-measure intraclass correlation coefficients within groups were fair to poor (0.36 to 0.40). Average-measure intraclass correlation coefficients were more reliable (0.811 to 0.840). Mean gestalt ratings by attending physicians correlated strongly with those by medical students (r=0.92) and residents (r=0.99). The generalizability coefficient was 0.91 for the complete data set. The decision study found that 42 gestalt ratings were required to reliably evaluate quality (>0.8). The mean gestalt quality ratings of blog posts between medical students, residents, and attending physicians correlate strongly, but individual ratings are unreliable. With sufficient raters, mean gestalt ratings provide a community standard for assessment. Copyright © 2017 American College of Emergency

  16. Vliv duševního života na tělesnost v gestalt terapii

    OpenAIRE

    Legátová, Natália

    2011-01-01

    This thesis attempts to investigate the possibilities for application of Gestalt therapy to deal with psychosomatic problems. The induction of thesis presents the development of Gestalt psychology from its beginning until today. The next section highlights the differences in other psychotherapeutic approaches, specifically deal with Daseinanalysis, which has a different approach to a holistic understanding of man. On the other hand, thesis attempts to map the same statements with psychosomati...

  17. Mechanism of human natural killer cell activation by Haemophilus ducreyi.

    Science.gov (United States)

    Li, Wei; Janowicz, Diane M; Fortney, Kate R; Katz, Barry P; Spinola, Stanley M

    2009-08-15

    The role of natural killer (NK) cells in the host response to Haemophilus ducreyi infection is unclear. In pustules obtained from infected human volunteers, there was an enrichment of CD56bright NK cells bearing the activation markers CD69 and HLA-DR, compared with peripheral blood. To study the mechanism by which H. ducreyi activated NK cells, we used peripheral blood mononuclear cells from uninfected volunteers. H. ducreyi activated NK cells only in the presence of antigen-presenting cells. H. ducreyi-infected monocytes and monocyte-derived macrophages activated NK cells in a contact- and interleukin-18 (IL-18)-dependent manner, whereas monocyte-derived dendritic cells induced NK activation through soluble IL-12. More lesional NK cells than peripheral blood NK cells produced IFN-gamma in response to IL-12 and IL-18. We conclude that NK cells are recruited to experimental lesions and likely are activated by infected macrophages and dendritic cells. IFN-gamma produced by lesional NK cells may facilitate phagocytosis of H. ducreyi.

  18. Mechanical stimulation improves tissue-engineered human skeletal muscle

    Science.gov (United States)

    Powell, Courtney A.; Smiley, Beth L.; Mills, John; Vandenburgh, Herman H.

    2002-01-01

    Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and allowing the cells to differentiate for 8 to 16 days. The resulting HBAMs are representative of skeletal muscle in that they contain parallel arrays of postmitotic myofibers; however, they differ in many other morphological characteristics. To engineer improved HBAMs, i.e., more in vivo-like, we developed Mechanical Cell Stimulator (MCS) hardware to apply in vivo-like forces directly to the engineered tissue. A sensitive force transducer attached to the HBAM measured real-time, internally generated, as well as externally applied, forces. The muscle cells generated increasing internal forces during formation which were inhibitable with a cytoskeleton depolymerizer. Repetitive stretch/relaxation for 8 days increased the HBAM elasticity two- to threefold, mean myofiber diameter 12%, and myofiber area percent 40%. This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue.

  19. Mechanical stimulation improves tissue-engineered human skeletal muscle

    Science.gov (United States)

    Powell, Courtney A.; Smiley, Beth L.; Mills, John; Vandenburgh, Herman H.

    2002-01-01

    Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and allowing the cells to differentiate for 8 to 16 days. The resulting HBAMs are representative of skeletal muscle in that they contain parallel arrays of postmitotic myofibers; however, they differ in many other morphological characteristics. To engineer improved HBAMs, i.e., more in vivo-like, we developed Mechanical Cell Stimulator (MCS) hardware to apply in vivo-like forces directly to the engineered tissue. A sensitive force transducer attached to the HBAM measured real-time, internally generated, as well as externally applied, forces. The muscle cells generated increasing internal forces during formation which were inhibitable with a cytoskeleton depolymerizer. Repetitive stretch/relaxation for 8 days increased the HBAM elasticity two- to threefold, mean myofiber diameter 12%, and myofiber area percent 40%. This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue.

  20. Role of compensatory meiosis mechanisms in human spermatogenesis.

    Science.gov (United States)

    Borgers, Mareike; Wolter, Martin; Hentrich, Anna; Bergmann, Martin; Stammler, Angelika; Konrad, Lutz

    2014-09-01

    Disturbances of checkpoints in distinct stages of spermatogenesis (mitosis, meiosis, and spermiogenesis) contribute to impaired spermatogenesis; however, the efficiency of meiotic entry has not been investigated in more detail. In this study, we analyzed azoospermic patients with defined spermatogenic defects by the use of octamer-binding protein 2 for type A spermatogonia, sarcoma antigen 1 for mitosis-meiosis transition and SMAD3 for pachytene spermatocytes. Especially patients with maturation arrest (MA) at the level of primary spermatocytes showed significantly reduced numbers of spermatogonia compared with patients with histologically intact spermatogenesis or patients with hypospermatogenesis (Hyp). For a detailed individual classification of the patients, we distinguished between 'high efficiency of meiotic entry' (high numbers of pachytene spermatocytes) and 'low efficiency of meiotic entry' (low numbers of pachytene spermatocytes). Only patients with histologically normal spermatogenesis (Nsp) and patients with Hyp showed normal numbers of spermatogonia and a high efficiency of meiotic entry. Of note, only patients with histologically Nsp or patients with Hyp could compensate low numbers of spermatogonia with a high efficiency of meiotic entry. In contrast, patients with MA always showed a low efficiency of meiotic entry. This is the first report on patients with impaired spermatogenesis, showing that half of the patients with Hyp but all patients with MA cannot compensate reduced numbers in spermatogonia with a highly efficient meiosis. Thus, we suggest that compensatory meiosis mechanisms in human spermatogenesis exist.

  1. Mechanical properties of human autologous tubular connective tissues (human biotubes) obtained from patients undergoing peritoneal dialysis.

    Science.gov (United States)

    Nakayama, Yasuhide; Kaneko, Yoshiyuki; Takewa, Yoshiaki; Okumura, Noriko

    2016-10-01

    Completely autologous in vivo tissue-engineered connective tissue tubes (Biotubes) have promise as arterial vascular grafts in animal implantation studies. In this clinical study of patients undergoing peritoneal dialysis (PD) (n = 11; age: 39-83 years), we evaluated human Biotubes' (h-Biotubes) mechanical properties to determine whether Biotubes with feasibility as vascular grafts could be formed in human bodies. We extracted PD catheters, embedded for 4-47 months, and obtained tubular connective tissues as h-Biotubes (internal diameter: 5 mm) from around the catheter' silicone tubular parts. h-Biotubes were composed mainly of collagen with smooth luminal surfaces. The average wall thickness was 278 ± 178 μm. No relationship was founded between the tubes' mechanical properties and patients' ages or PD catheter embedding periods statistically. However, the elastic modulus (2459 ± 970 kPa) and tensile strength (623 ± 314 g) of h-Biotubes were more than twice as great as those from animal Biotubes, formed from the same PD catheters by embedding in the beagle subcutaneous pouches for 1 month, or beagle arteries. The burst strength (6338 ± 1106 mmHg) of h-Biotubes was almost the same as that of the beagle thoracic or abdominal aorta. h-Biotubes could be formed in humans over a 4-month embedding period, and they satisfied the mechanical requirements for application as vascular grafts. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 1431-1437, 2016.

  2. As implicações filosóficas da teoria da Gestalt

    OpenAIRE

    Jonas Fornitano Cholfe

    2009-01-01

    A Teoria da Gestalt, cujos fundamentos são erigidos no intercâmbio entre as idéias de Köhler, Koffka e Wertheimer, tem como objetivo principal o restabelecimento do vínculo entre a ciência e a vida humana. A noção de Gestalt, pensada como uma entidade da qual o sentido e o valor são características intrínsecas, constitui-se como a chave desse empreendimento. Partindo da tese fenomenológica, da defesa de que a elucidação conceitual exige o retorno aos dados da experiência direta, os gestaltist...

  3. Speech-rhythm characteristics of client-centered, Gestalt, and rational-emotive therapy interviews.

    Science.gov (United States)

    Chen, C L

    1981-07-01

    The aim of this study was to discover whether client-centered, Gestalt, and rational-emotive psychotherapy interviews could be described and differentiated on the basis of quantitative measurement of their speech rhythms. These measures were taken from the sound portion of a film showing interviews by Carl Rogers, Frederick Perls, and Albert Ellis. The variables used were total session and percentage of speaking times, speaking turns, vocalizations, interruptions, inside and switching pauses, and speaking rates. The three types of interview had very distinctive patterns of speech-rhythm variables. These patterns suggested that Rogers's Client-centered therapy interview was patient dominated, that Ellis's rational-emotive therapy interview was therapist dominated, and that Perls's Gestalt therapy interview was neither therapist nor patient dominated.

  4. Preexposure effects in spatial learning: From gestaltic to associative and attentional cognitive maps

    Directory of Open Access Journals (Sweden)

    Edward S. Redhead

    2002-01-01

    Full Text Available In this paper a series of studies and theoretical proposals about how preexposure to environmental cues affects subsequent spatial learning are reviewed. Traditionally, spatial learning had been thought to depend on gestaltic non-associative processes, and well established phenomena such as latent learning or instantaneous transfer have been taken to provide evidence for this sort of cognitive mapping. However, reviewing the literature examining these effects reveals that there is no need to advocate for gestaltic processes since standard associative learning theory provides an adequate framework for accounting for navigation skills. Recent studies reveal that attentional processes play a role in spatial learning. The need for an integrated attentional and associative approach to explain spatial learning is discussed.

  5. Quantum Mechanics and Molecular Mechanics Study of the Catalytic Mechanism of Human AMSH-LP Domain Deubiquitinating Enzymes.

    Science.gov (United States)

    Zhu, Wenyou; Liu, Yongjun; Ling, Baoping

    2015-08-25

    Deubiquitinating enzymes (DUBs) catalyze the cleavage of the isopeptide bond in polyubiquitin chains to control and regulate the deubiquitination process in all known eukaryotic cells. The human AMSH-LP DUB domain specifically cleaves the isopeptide bonds in the Lys63-linked polyubiquitin chains. In this article, the catalytic mechanism of AMSH-LP has been studied using a combined quantum mechanics and molecular mechanics method. Two possible hydrolysis processes (Path 1 and Path 2) have been considered. Our calculation results reveal that the activation of Zn(2+)-coordinated water molecule is the essential step for the hydrolysis of isopeptide bond. In Path 1, the generated hydroxyl first attacks the carbonyl group of Gly76, and then the amino group of Lys63 is protonated, which is calculated to be the rate limiting step with an energy barrier of 13.1 kcal/mol. The energy barrier of the rate limiting step and the structures of intermediate and product are in agreement with the experimental results. In Path 2, the protonation of amino group of Lys63 is prior to the nucleophilic attack of activated hydroxyl. The two proton transfer processes in Path 2 correspond to comparable overall barriers (33.4 and 36.1 kcal/mol), which are very high for an enzymatic reaction. Thus, Path 2 can be ruled out. During the reaction, Glu292 acts as a proton transfer mediator, and Ser357 mainly plays a role in stabilizing the negative charge of Gly76. Besides acting as a Lewis acid, Zn(2+) also influences the reaction by coordinating to the reaction substrates (W1 and Gly76).

  6. La teoria della Gestalt. Figure, temi di interesse e prospettive per la didattica

    OpenAIRE

    Zudini, Verena

    2014-01-01

    A partire da una breve rassegna degli studiosi principali e dei temi da questi sviluppati nel contesto della teoria della Gestalt, se ne considereranno aspetti di rilievo per la didattica, in particolare della matematica. Si mostrerà come tali aspetti risultino quanto mai attuali nelle analisi cognitive e come il loro approfondimento possa essere utile per capire soprattutto in quali direzioni orientare la ricerca futura. Starting from a brief survey on the most authoritative scholar...

  7. With Doug: an Eastern Orthodox--Gestalt framework for pastoral psychotherapy in the armed forces.

    Science.gov (United States)

    Alexander, David

    2013-01-01

    In military behavioral healthcare, a short-term, solutions-focused system often privileges cognitive techniques over existential, affective, or psychodynamic approaches to care. Pastoral psychotherapy, which often privileges existential and person-centered care, has the potential to prove a pivotal complement in treating the whole person. This article offers an existential approach to pastoral psychotherapy in the military using integrated concepts and applications from Gestalt Therapy and Eastern Orthodox pastoral care.

  8. Measuring Growth and Decline in Visual-Motor Processes with the Bender-Gestalt Second Edition

    Science.gov (United States)

    Decker, Scott L.

    2008-01-01

    The purpose of this study is to develop a change-sensitive scale for evaluating developmental change in visual-motor ability across the life span. A partial-credit item-response model is used to estimate theta values for each age group between 4 and 90 using the Bender-Gestalt II standardization sample (N = 4,000). Results from this study suggest…

  9. A patient with a large pulmonary saddle embolus eluding both clinical gestalt and validated decision rules.

    Science.gov (United States)

    Hennessey, Adam; Setyono, Devy A; Lau, Wayne Bond; Fields, Jason Matthew

    2012-06-01

    We report a patient with chest pain who was classified as having low risk for pulmonary embolism with clinical gestalt and accepted clinical decision rules. An inadvertently ordered D-dimer and abnormal result, however, led to the identification of a large saddle embolus. This case illustrates the fallibility of even well-validated decision aids and that an embolism missed by these tools is not necessarily low risk or indicative of a low clot burden. Copyright © 2011. Published by Mosby, Inc.

  10. THE INCIDENCE OF BENDER-GESTALT FIGURE DEVIATIONS IN A GROUP OF MENTALLY RETARDED PSYCHIATRIC PATIENTS

    Directory of Open Access Journals (Sweden)

    Habibollah Ghassemzadeh

    1994-06-01

    Full Text Available The Bender-Gestalt Test was given to thirty mentally-retarded psychiatric patients. The mean, standard deviation, and standard error were 56.73, 26.25, and 4.80 respectively. Rotation was the most frequent major deviation which occurred in all the designs."nDesign # 7 was the most difficult one to be reproduced in the sample. This design by itself, was subject to 47% of distortion, 79% of omission, and 21% of rotation.

  11. A GENTLER GESTALT THERAPY: ON REDUCING STIMULATION IN ADULT SURVIVORS OF ABUSE

    OpenAIRE

    Andrew Lapides

    2012-01-01

    Adult survivors of abuse require a slower progression in treatment. Profoundly abused patients suffering from pre-oedipal conditions may become overstimulated using gestalt methods. This paper will focus on reducing stimulation in the patient using methods borrowed from modern psychoanalysis, which was developed by Hyman Spotnitz. The author argues for a combined approach that emphasizes support rather then frustration in the development of the treatment process.

  12. Dynamics of Psychological Crisis Experience With Psychological Consulting by Gestalt Therapy Methods

    OpenAIRE

    Fahrutdinova, Liliya Raifovna; Nugmanova, Dzhamilia Renatovna

    2014-01-01

    Dynamics of experience as such and its corporeal, emotional and cognitive elements in the situation of psychological consulting provisioning is covered. The aim of research was to study psychological crisis experience dynamics in the situation when psychological consulting by gestalt therapy methods is provided. Theoretical analysis of the problem of crisis situations, phenomenon and structural, and dynamic organization of experience of the subject of consulting have been carried out. To fulf...

  13. A GENTLER GESTALT THERAPY: ON REDUCING STIMULATION IN ADULT SURVIVORS OF ABUSE

    Directory of Open Access Journals (Sweden)

    Andrew Lapides

    2012-04-01

    Full Text Available Adult survivors of abuse require a slower progression in treatment. Profoundly abused patients suffering from pre-oedipal conditions may become overstimulated using gestalt methods. This paper will focus on reducing stimulation in the patient using methods borrowed from modern psychoanalysis, which was developed by Hyman Spotnitz. The author argues for a combined approach that emphasizes support rather then frustration in the development of the treatment process.

  14. Measuring Growth and Decline in Visual-Motor Processes with the Bender-Gestalt Second Edition

    Science.gov (United States)

    Decker, Scott L.

    2008-01-01

    The purpose of this study is to develop a change-sensitive scale for evaluating developmental change in visual-motor ability across the life span. A partial-credit item-response model is used to estimate theta values for each age group between 4 and 90 using the Bender-Gestalt II standardization sample (N = 4,000). Results from this study suggest…

  15. Gestalt perception and the decline of global precedence in older subjects.

    Science.gov (United States)

    Staudinger, Markus R; Fink, Gereon R; Mackay, Clare E; Lux, Silke

    2011-01-01

    Our visual world is hierarchically organized. Hierarchical processing is frequently investigated using Navon figures (large letters made up of smaller ones). In young adults, many studies reported faster reaction times (RT) to target letters presented at the global level [i.e., global precedence (GP)]. Furthermore, an age-related decline of this GP has been reported. We tested whether deficits in perceptual grouping via Gestalt laws (Gestalt principles of Proximity and Continuity) might contribute to this decline. In a directed attention task with valid and invalid cues, 20 young (mean age 22) and 20 older (mean age 57) male subjects had to indicate whether a target letter appeared at the global or local level of a Navon figure. The number of local letters forming the global figure was modulated in 5 steps. As expected, during valid trials, young adults showed a GP that linearly increased with increasing numbers of local letters (i.e., GP enhancement). This suggests that GP is related to perceptual grouping via Gestalt laws. By contrast, the group of older subjects demonstrated no precedence effect in RT and a non-significant trend toward GP in error rates (ER). No GP enhancement with an increasing number of local elements was observed. Exploratory analysis revealed that individual insensitivity to the modulation of matrix density, as revealed by a lack of global RT acceleration, was restricted to subjects that showed an overall local precedence (LP). Because older subjects tended to more frequently display an insensitivity to matrix modulation and an LP, we conclude that deficient Gestalt detection as indicated by non-enhanced global RT might contribute to the RT-related decline of GP with age. Copyright © 2010 Elsevier Srl. All rights reserved.

  16. Dynamics of psychological crisis experience with psychological consulting by gestalt therapy methods.

    Science.gov (United States)

    Fahrutdinova, Liliya Raifovna; Nugmanova, Dzhamilia Renatovna

    2015-01-01

    Dynamics of experience as such and its corporeal, emotional and cognitive elements in the situation of psychological consulting provisioning is covered. The aim of research was to study psychological crisis experience dynamics in the situation when psychological consulting by gestalt therapy methods is provided. Theoretical analysis of the problem of crisis situations, phenomenon and structural, and dynamic organization of experience of the subject of consulting have been carried out. To fulfill research project test subjects experience crisis situation have been selected, studied in the situation when they provided psychological consulting by methods of gestalt therapy, and methodology of study of crisis situations experience has been prepared. Specifics of psychological crisis experience have been revealed and its elements in different stages of psychological consulting by gestalt therapy methods. Dynamics of experience of psychological crisis and its structural elements have been revealed and reliable changes in it have been revealed. Dynamics of psychological crisis experience and its structural elements have been revealed and reliable changes in it have been revealed. "Desiccation" of experience is being observed, releasing its substantiality of negative impression to the end of consulting and development of the new experience of control over crisis situation. Interrelations of structural elements of experience in the process of psychological consulting have been shown. Effecting one structure causes reliable changes in all others structural elements of experience. Giving actual psychological help to clients in crisis situation by methods of gestalt therapy is possible as it was shown in psychological consulting sessions. Structure of client's request has been revealed - problems of personal sense are fixed as the most frequent cause of clients' applications, as well as absence of choices, obtrusiveness of negative thoughts, tend to getting stuck on events

  17. Assessing the influence of gestalt-type characteristics on preferences over lifetime health profiles.

    Science.gov (United States)

    Oliver, Adam

    2008-01-01

    In contrast to the basic tenets of economic theory, there is substantial evidence that people's remembered and predicted utility of events systematically differs from the utility that they experience. These systematic differences are caused by "gestalt characteristics.'' The objective of this study was to test whether people maximize quality-adjusted life years (QALYs), or whether QALY maximization is compromised by their being influenced by factors that resemble the gestalt characteristics when choosing between lifetime health profiles. Time trade-off values were elicited from 50 respondents, who were also presented with a series of hypothetical questions that each depicted 2 lifetime health profiles. The respondents were asked to choose which of the 2 profiles in each question they would prefer to experience. By inputting the values that the respondents placed on the health states into the lifetime health profiles, it was possible to observe whether their answers were consistent with QALY maximization or with various hypothesized gestalt-type effects. Across decisions that involve a simple trade-off between the length of life and the quality of the health state, choices consistent with QALY maximizing were relatively common, although even here approximately half of the respondents violated this rule. Consistency with QALY maximization was lower in most of the other tests and indicated that many people might, for example, prefer to trade off some lifetime health to experience a good end to life, or to avoid highly unstable lifetime health profiles. The respondents' answers were often consistent with the hypothesized gestalt-type effects, but it is probable that for some of the questions the characteristics themselves were not driving the respondents' answers and that factors such as complex rates of discounting might have played a role. However, whatever the driving motivation behind the respondents' answers, the important point to note from this study is that

  18. Religion in human evolution: on some generative and selective mechanisms

    DEFF Research Database (Denmark)

    Jensen, Jeppe Sinding

    2012-01-01

    On the use of moral psychology in reconstructing the evolutionary role of religion in human social development......On the use of moral psychology in reconstructing the evolutionary role of religion in human social development...

  19. The Effectiveness of Gestalt Therapy and Cognitive Therapy on Improvement of Life Quality of War Veterans

    Directory of Open Access Journals (Sweden)

    S Sadeghi

    2012-02-01

    Full Text Available Background & Aim: The imposed war burdened a lot of problems on the society of Iran during the past few years. In this course, veterans didn’t immune from its harmful effects. The aim of the present study was to determine the effectiveness of integrated group gestalt therapy and cognitive therapy on improvement of quality of life of veterans of city of Jahrom, Iran. Methods: The present clinical trial study was conducted on thirty veterans of Jahrom in 2010. The subjects included all the war veterans of Jahrom, 820 with 25-69 percent physical damage. Random sampling was executed and the world Health Organization life quality questionnaire (WHOQOL-BREF was given to 150 of them. Fifteen people in each group were replaced by another fifteen people. The test group received eight sessions of group consultation in Gestalt therapy and cognition therapy ways, but the control group received no therapy. The gathered data was analyzed using ANOVA test. Results: The result of this study showed that-there is a significant difference between the life quality dimensions (physical health, mental health, life environment and social relations between the test and control group (p=0.001. Conclusion: The results of this study showed that the integrated of group counseling by gestalt therapy and cognitive therapy had an influence on increasing the veteran’s life qualifications in aspects of physical health, mental health, life environment and social relations.

  20. A Gestalt-terapia na universidade: da f(ôrma à boa forma

    Directory of Open Access Journals (Sweden)

    Luciana Loyola Madeira Soares

    2009-04-01

    Full Text Available Este texto apresenta uma discussão sobre as características do trabalho de supervisão em Gestalt-terapia nos Serviços de Psicologia Aplicada dos cursos de graduação em Psicologia. Com uma presença que ainda pode ser considerada recente na universidade, a Gestalt-terapia propõe uma abordagem no estágio em Psicologia Clínica que não se confunde com uma formação de gestalt-terapeutas. Sua estratégia passa pelo desdobramento de possibilidades criativas da relação do supervisor com o estagiário e, deste, com os clientes em atendimento. A condução do trabalho na supervisão visa à melhor forma possível para configurar a singularidade do aprendizado das habilidades do futuro psicólogo clínico, e, para isso, distancia-se da rigidez das formatações teóricas e de um enquadramento fechado em dispositivos técnicos.

  1. Studies with lucid dreaming as add-on therapy to Gestalt therapy.

    Science.gov (United States)

    Holzinger, B; Klösch, G; Saletu, B

    2015-06-01

    The aim of the present exploratory clinical study was to evaluate LD as an add-on therapy for treating nightmares. Thirty-two subjects having nightmares (ICD-10: F51.5) at least twice a week participated. Subjects were randomly assigned to group: A) Gestalt therapy group (= GTG), or B) Gestalt and lucid dreaming group therapy (= LDG). Each group lasted ten weeks. Participants kept a sleep/dream diary over the treatment. Examinations with respect to nightmare frequency and sleep quality (Pittsburgh Sleep Quality Index) were carried out at the beginning, after five and ten weeks and at a follow-up three months later. Concerning nightmare frequency, a significant reduction was found in both groups after the ten-week-study and at the follow-up (Wilcoxon test: P ≤ 0.05). Significant reduction in dream recall frequency could only be observed in the GTG (Wilcoxon test: P ≤ 0.05). For subjects having succeeded in learning lucid dreaming, reduction was sooner and higher. Sleep quality improved for both groups at the follow-up (P ≤ 0.05, Wilcoxon test). Only the LDG showed significant improvement at the end of therapy (P ≤ 0.05). Lucid dreaming, in combination with Gestalt therapy, is a potent technique to reduce nightmare frequency and improve the subjective quality of sleep. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Understanding human action: integrating meanings, mechanisms, causes, and contexts

    NARCIS (Netherlands)

    M. Keestra

    2012-01-01

    Humans are capable of understanding an incredible variety of actions performed by other humans. Even though these range from primary biological actions like eating and fleeing, to acts in parliament or in poetry, humans generally can make sense of each other’s actions. Understanding other people’s a

  3. Understanding human action: integrating meanings, mechanisms, causes, and contexts

    NARCIS (Netherlands)

    Keestra, M.; Repko, A.F.; Newell, W.H.; Szostak, R.

    2012-01-01

    Humans are capable of understanding an incredible variety of actions performed by other humans. Even though these range from primary biological actions like eating and fleeing, to acts in parliament or in poetry, humans generally can make sense of each other’s actions. Understanding other people’s

  4. Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle.

    Directory of Open Access Journals (Sweden)

    Mark E Wylam

    Full Text Available Cigarette smoke contributes to or exacerbates airway diseases such as asthma and COPD, where airway hyperresponsiveness and airway smooth muscle (ASM proliferation are key features. While factors such as inflammation contribute to asthma in part by enhancing agonist-induced intracellular Ca(2+ ([Ca(2+]i responses of ASM, the mechanisms by which cigarette smoke affect ASM are still under investigation. In the present study, we tested the hypothesis that cigarette smoke enhances the expression and function of Ca(2+ regulatory proteins leading to increased store operated Ca(2+ entry (SOCE and cell proliferation. Using isolated human ASM (hASM cells, incubated in the presence and absence cigarette smoke extract (CSE we determined ([Ca(2+]i responses and expression of relevant proteins as well as ASM proliferation, reactive oxidant species (ROS and cytokine generation. CSE enhanced [Ca(2+]i responses to agonist and SOCE: effects mediated by increased expression of TRPC3, CD38, STIM1, and/or Orai1, evident by attenuation of CSE effects when siRNAs against these proteins were used, particularly Orai1. CSE also increased hASM ROS generation and cytokine secretion. In addition, we found in the airways of patients with long-term smoking history, TRPC3 and CD38 expression were significantly increased compared to life-long never-smokers, supporting the role of these proteins in smoking effects. Finally, CSE enhanced hASM proliferation, an effect confirmed by upregulation of PCNA and Cyclin E. These results support a critical role for Ca(2+ regulatory proteins and enhanced SOCE to alter airway structure and function in smoking-related airway disease.

  5. Physiological and Biomechanical Mechanisms of Distance Specific Human Running Performance.

    Science.gov (United States)

    Thompson, M A

    2017-08-01

    Running events range from 60-m sprints to ultra-marathons covering 100 miles or more, which presents an interesting diversity in terms of the parameters for successful performance. Here, we review the physiological and biomechanical variations underlying elite human running performance in sprint to ultramarathon distances. Maximal running speeds observed in sprint disciplines are achieved by high vertical ground reaction forces applied over short contact times. To create this high force output, sprint events rely heavily on anaerobic metabolism, as well as a high number and large cross-sectional area of type II fibers in the leg muscles. Middle distance running performance is characterized by intermediates of biomechanical and physiological parameters, with the possibility of unique combinations of each leading to high-level performance. The relatively fast velocities in mid-distance events require a high mechanical power output, though ground reaction forces are less than in sprinting. Elite mid-distance runners exhibit local muscle adaptations that, along with a large anaerobic capacity, provide the ability to generate a high power output. Aerobic capacity starts to become an important aspect of performance in middle distance events, especially as distance increases. In distance running events, V˙O2max is an important determinant of performance, but is relatively homogeneous in elite runners. V˙O2 and velocity at lactate threshold have been shown to be superior predictors of elite distance running performance. Ultramarathons are relatively new running events, as such, less is known about physiological and biomechanical parameters that underlie ultra-marathon performance. However, it is clear that performance in these events is related to aerobic capacity, fuel utilization, and fatigue resistance. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology 2017. This work is written by US Government employees and is in

  6. Bender Visual-Motor Gestalt Test in adolescents: relationship between visual-motor development and the Tanner Stages.

    Science.gov (United States)

    Keppeke, Lívia de Freitas; Cintra, Isa de Pádua; Schoen, Teresa Helena

    2013-08-01

    Visual-motor skill is fundamental to human development and is an important component of psychological evaluations. The goal of the present study was to determine whether there is a correlation between visual-motor development, as measured by the Bender Visual-Motor Gestalt Test (Bender test), and sexual maturity in adolescents, based on the Tanner Stages in Adolescents. 134 adolescents from 10 to 15 years of age participated in the study. The Bender test and the Raven's Progressive Matrices Test were employed. The measures were administered individually and information on sexual maturity and the presence of developmental disorders was collected from medical charts. The results of the Bender test were not affected by gender, age, schooling, or changes stemming from puberty, but were significantly affected by having repeated a school year and by developmental disorders. An association was found with Raven's scores. The Bender test proved sensitive to developmental disorders in adolescence. No association was found between visual-motor development and sexual maturity in adolescents.

  7. The Geographic Distribution of Human Capital: Measurement of Contributing Mechanisms

    OpenAIRE

    2010-01-01

    This paper investigates how the geographic distribution of human capital evolves over time. With U.S. data, I decompose generation-to-generation changes in local human capital into three factors: the previous generation’s human capital, intergenerational transmission of skills from parents to their children, and migration of the children. I find evidence of regression to the mean of local skills at the state level and divergence at the commuting zone level. Labor market size, climate, local c...

  8. Construct validity of the Bender-Gestalt II: comparison with Wechsler Intelligence Scale for Children-III.

    Science.gov (United States)

    Decker, Scott L; Allen, Ryan; Choca, James P

    2006-02-01

    This study investigated the relationships of visuomotor constructs as measured by the Bender-Gestalt II with the subtests of the WISC-III. A factor analysis included the standardized Copy and Recall scores of the Bender-Gestalt II and subtest scores of the WISC-III. The Copy score was predicted to load on measures of visual and spatial thinking and the Recall score on a short-term memory factor. The results of a principal components analysis suggest a four-factor solution with the Bender-Gestalt II Copy score loading on a visual and spatial thinking factor primarily with WISC-III Perceptual Organization subtests. The Recall score loaded on a visual and spatial thinking factor as well as a short-term memory factor with the WISC-III Digit Span subtest. The results suggest the Bender-Gestalt II Copy subtest shared commonality with the visual and spatial tasks given the similarity in the visuomotor demands of each test and was less influenced by processing speed or cultural knowledge than other tests on the visual and spatial thinking factor. Also, results suggest Bender-Gestalt II Recall measures elements of both visual and spatial thinking as well as aspects of short-term memory and memory retrieval. Clinical guidelines for co-administration and underlying processing demands are discussed.

  9. Molecular adaptations in human atrial fibrillation : mechanisms of protein remodeling

    NARCIS (Netherlands)

    Brundel, Bianca Johanna Josephina Maria

    2000-01-01

    The main goal was to study the molecular remodeling in human atrial fibrillation. We focussed on gene expression of proteins wich influence the calcium homeostasis and action potential duration in human AF. The impact of modulation sysems like the natriuretic peptide system and the endothelin system

  10. Drugs associated with teratogenic mechanisms. Part II : a literature review of the evidence on human risks

    NARCIS (Netherlands)

    van Gelder, Marleen M. H. J.; de Jong-van den Berg, Lolkje T. W.; Roeleveld, Nel

    2014-01-01

    What is the current state of knowledge on the human risks of drugs suspected to be associated with teratogenic mechanisms? Evidence for the presence or absence of human risks of birth defects is scarce or non-existent for the majority of drugs associated with teratogenic mechanisms. Medical drugs su

  11. Sequence-level mechanisms of human epigenome evolution.

    Science.gov (United States)

    Prendergast, James G D; Chambers, Emily V; Semple, Colin A M

    2014-06-24

    DNA methylation and chromatin states play key roles in development and disease. However, the extent of recent evolutionary divergence in the human epigenome and the influential factors that have shaped it are poorly understood. To determine the links between genome sequence and human epigenome evolution, we examined the divergence of DNA methylation and chromatin states following segmental duplication events in the human lineage. Chromatin and DNA methylation states were found to have been generally well conserved following a duplication event, with the evolution of the epigenome largely uncoupled from the total number of genetic changes in the surrounding DNA sequence. However, the epigenome at tissue-specific, distal regulatory regions was observed to be unusually prone to diverge following duplication, with particular sequence differences, altering known sequence motifs, found to be associated with divergence in patterns of DNA methylation and chromatin. Alu elements were found to have played a particularly prominent role in shaping human epigenome evolution, and we show that human-specific AluY insertion events are strongly linked to the evolution of the DNA methylation landscape and gene expression levels, including at key neurological genes in the human brain. Studying paralogous regions within the same sample enables the study of the links between genome and epigenome evolution while controlling for biological and technical variation. We show DNA methylation and chromatin divergence between duplicated regions are linked to the divergence of particular genetic motifs, with Alu elements having played a disproportionate role in the evolution of the epigenome in the human lineage.

  12. Region-specific mechanical properties of the human patella tendon

    DEFF Research Database (Denmark)

    Haraldsson, B T; Aagaard, P; Krogsgaard, M

    2004-01-01

    . A stereoscopic microscope equipped with a digital camera recorded elongation. The fascicles were preconditioned five cycles before the failure test based on pilot data on rat tendon fascicle. Human fascicle length increased with repeated cycles (P

  13. PET FACE: MECHANISMS UNDERLYING HUMAN-ANIMAL RELATIONSHIPS

    Directory of Open Access Journals (Sweden)

    Marta eBorgi

    2016-03-01

    Full Text Available Accumulating behavioral and neurophysiological studies support the idea of infantile (cute faces as highly biologically relevant stimuli rapidly and unconsciously capturing attention and eliciting positive/affectionate behaviors, including willingness to care. It has been hypothesized that the presence of infantile physical and behavioral features in companion (or pet animals (i.e. dogs and cats might form the basis of our attraction to these species. Preliminary evidence has indeed shown that the human attentional bias toward the baby schema may extend to animal facial configurations. In this review, the role of facial cues, specifically of infantile traits and facial signals (i.e. eyes gaze as emotional and communicative signals is highlighted and discussed as regulating human-animal bond, similarly to what can be observed in the adult-infant interaction context. Particular emphasis is given to the neuroendocrine regulation of social bond between humans and animals through oxytocin secretion. Instead of considering companion animals as mere baby substitutes for their owners, in this review we highlight the central role of cats and dogs in human lives. Specifically, we consider the ability of companion animals to bond with humans as fulfilling the need for attention and emotional intimacy, thus serving similar psychological and adaptive functions as human-human friendships. In this context, facial cuteness is viewed not just as a releaser of care/parental behavior, but more in general as a trait motivating social engagement. To conclude, the impact of this information for applied disciplines is briefly described, particularly in consideration of the increasing evidence of the beneficial effects of contacts with animals for human health and wellbeing.

  14. Patterns of Selection of Human Movements IV: Energy Efficiency, Mechanical Advantage, and Asynchronous Arm-Cranking

    OpenAIRE

    Hagler, Stuart

    2017-01-01

    Human movements are physical processes combining the classical mechanics of the human body moving in space and the biomechanics of the muscles generating the forces acting on the body under sophisticated sensory-motor control. The characterization of the performance of human movements is a problem with important applications in clinical and sports research. One way to characterize movement performance is through measures of energy efficiency that relate the mechanical energy of the body and m...

  15. Patterns of Selection of Human Movements III: Energy Efficiency, Mechanical Advantage, and Walking Gait

    OpenAIRE

    Hagler, Stuart

    2016-01-01

    Human movements are physical processes combining the classical mechanics of the human body moving in space and the biomechanics of the muscles generating the forces acting on the body under sophisticated sensory-motor control. One way to characterize movement performance is through measures of energy efficiency that relate the mechanical energy of the body and metabolic energy expended by the muscles. We expect the practical utility of such measures to be greater when human subjects execute m...

  16. Insights into the phosphatase and the synthase activities of human bisphosphoglycerate mutase: a quantum mechanics/molecular mechanics simulation.

    Science.gov (United States)

    Chu, Wen-Ting; Zheng, Qing-Chuan; Zhang, Hong-Xing

    2014-03-07

    Bisphosphoglycerate mutase (BPGM) is a multi-activity enzyme. Its main function is to synthesize the 2,3-bisphosphoglycerate, the allosteric effector of hemoglobin. This enzyme can also catalyze the 2,3-bisphosphoglycerate to the 3-phosphoglycerate. In this study, the reaction mechanisms of both the phosphatase and the synthase activities of human bisphosphoglycerate mutase were theoretically calculated by using the quantum mechanics/molecular mechanics method based on the metadynamics and umbrella sampling simulations. The simulation results not only show the free energy curve of the phosphatase and the synthase reactions, but also reveal the important role of some residues in the active site. Additionally, the energy barriers of the two reactions indicate that the activity of the synthase in human bisphosphoglycerate mutase is much higher than that of the phosphatase. The estimated reaction barriers are consistent with the experimental data. Therefore, our work can give important information to understand the catalytic mechanism of the bisphosphoglycerate mutase family.

  17. On the mechanical behavior of the human biliary system

    Institute of Scientific and Technical Information of China (English)

    Xiaoyu Luo; Wenguang Li; Nigel Bird; Swee Boon Chin; NA Hill; Alan G Johnson

    2007-01-01

    This paper reviews the progress made in understanding the mechanical behaviour of the biliary system.Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous gallbladder pain often pose diagnostic difficulties and undergo repeated ultrasound scans and oral cholecystograms. Moreover, surgery to remove the gallbladder in these patients, in an attempt to relieve the symptoms, gives variable results. Extensive research has been carried out to understand the physiological and pathological functions of the biliary system, but the mechanism of the pathogenesis of gallstones and pain production still remain poorly understood. It is believed that the mechanical factors play an essential role in the mechanisms of the gallstone formation and biliary diseases. However, despite the extensive literature in clinical studies, only limited work has been carried out to study the biliary system from the mechanical point of view. In this paper, we discuss the state of art knowledge of the fluid dynamics of bile flow in the biliary tract, the solid mechanics of the gallbladder and bile ducts, recent mathematical and numerical modelling of the system,and finally the future challenges in the area.

  18. Fuzzy synthetic evaluation on layoff mechanism for human resource

    Institute of Scientific and Technical Information of China (English)

    LEI Yong; PU Yong-jian

    2004-01-01

    According to the modern theory of human resource management, the condition of buyout mainly depends on two variables of an employee: his interior value of product and exterior work reward. There exist shortages in evaluating the value of the employees in an enterprise. Consequently, a lot of employees might be laid off. Hence, this paper puts forward a two-stage method for decision-making to carry out a selective plan of buyout, based on the fuzzy synthetic evaluation involing many factors impacting on human resource. Moreover, a positive analysis is also given.

  19. A psicologia da gestalt e a ciência empírica contemporânea

    OpenAIRE

    Arno Engelmann

    2002-01-01

    Wertheimer realizou um experimento que era explicado seguindo-se fatores holísticos gestálticos, e isto há mais de noventa anos. Apesar disso, estudos recentes demonstram a vivacidade desse tipo de explicação. Basicamente, ao se observar coisas do mundo, observa-se suas formas ou melhor suas Gestalten. A seguir, pode-se dividir essas Gestalten em partes. Porém cada parte será sempre parte daquela Gestalt que lhe deu inicio e não um elemento constituinte básico. A teoria da Gestalt não é exclu...

  20. Mechanically induced ankle inversion during human walking and jumping.

    NARCIS (Netherlands)

    Nieuwenhuijzen, P.H.J.A.; Grüneberg, C.; Duysens, J.E.J.

    2002-01-01

    A new method to study sudden ankle inversions during human walking and jumping is presented. Ankle inversions of 25 degrees were elicited using a box containing a trap door. During the gait task, subjects walked at a speed of 4 km/h. At a pre-programmed delay after left heel strike, an electromagnet

  1. Mechanically induced ankle inversion during human walking and jumping.

    NARCIS (Netherlands)

    Nieuwenhuijzen, P.H.J.A.; Grüneberg, C.; Duysens, J.E.J.

    2002-01-01

    A new method to study sudden ankle inversions during human walking and jumping is presented. Ankle inversions of 25 degrees were elicited using a box containing a trap door. During the gait task, subjects walked at a speed of 4 km/h. At a pre-programmed delay after left heel strike, an electromagnet

  2. The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis.

    Science.gov (United States)

    Fauci, Anthony S.

    1988-01-01

    Discusses how the infection of the human immunodeficiency virus (HIV) results in a profound immunosuppression due predominantly to a selective depletion of helper/inducer T lymphocytes that express the receptor for the virus, as well as neuropsychiatric abnormalities in the brain. (TW)

  3. A Century of Gestalt Psychology in Visual Perception II. Conceptual and Theoretical Foundations

    Science.gov (United States)

    Wagemans, Johan; Feldman, Jacob; Gepshtein, Sergei; Kimchi, Ruth; Pomerantz, James R.; van der Helm, Peter A.; van Leeuwen, Cees

    2012-01-01

    Our first review paper on the occasion of the centennial anniversary of Gestalt psychology focused on perceptual grouping and figure-ground organization. It concluded that further progress requires a reconsideration of the conceptual and theoretical foundations of the Gestalt approach, which is provided here. In particular, we review contemporary formulations of holism within an information-processing framework, allowing for operational definitions (e.g., integral dimensions, emergent features, configural superiority, global precedence, primacy of holistic/configural properties) and a refined understanding of its psychological implications (e.g., at the level of attention, perception, and decision). We also review four lines of theoretical progress regarding the law of Prägnanz—the brain’s tendency of being attracted towards states corresponding to the simplest possible organization, given the available stimulation. The first considers the brain as a complex adaptive system and explains how self-organization solves the conundrum of trading between robustness and flexibility of perceptual states. The second specifies the economy principle in terms of optimization of neural resources, showing that elementary sensors working independently to minimize uncertainty can respond optimally at the system level. The third considers how Gestalt percepts (e.g., groups, objects) are optimal given the available stimulation, with optimality specified in Bayesian terms. Fourth, Structural Information Theory explains how a Gestaltist visual system that focuses on internal coding efficiency yields external veridicality as a side-effect. To answer the fundamental question of why things look as they do, a further synthesis of these complementary perspectives is required. PMID:22845750

  4. The superior colliculus is sensitive to gestalt-like stimulus configuration in hemispherectomy patients.

    Science.gov (United States)

    Georgy, Loraine; Celeghin, Alessia; Marzi, Carlo A; Tamietto, Marco; Ptito, Alain

    2016-08-01

    Patients with cortical blindness following a lesion to the primary visual cortex (V1) may retain nonconscious visual abilities (blindsight). One intriguing, though largely unexplored question, is whether nonconscious vision in the blind hemifield of hemianopic patients can be sensitive to higher-order perceptual organization, and which V1-independent structure underlies such effect. To answer this question, we tested two rare hemianopic patients who had undergone hemispherectomy, and in whom the only post-chiasmatic visual structure left intact in the same side of the otherwise damaged hemisphere was the superior colliculus (SC). By using a variant of the redundant target effect (RTE), we presented single dots, patterns composed by the same dots organized in quadruple gestalt-like configurations, or patterns of four dots arranged in random configurations, either singly to the intact visual hemifield or bilaterally to both hemifields. As reported in a number of prior studies on blindsight patients, we found that bilateral stimulation yielded faster reaction times (RTs) than single stimulation of the intact field for all conditions (i.e., there was an implicit RTE). In addition to this effect, both patients showed a further speeding up of RTs when the gestalt-like, but not the random shape, quadruple patterns were projected to their blind hemifield during bilateral stimulation. Because other retino-recipient subcortical and cortical structures in the damaged hemisphere are absent, the SC on the lesioned side seems solely responsible for such an effect. The present results provide initial support to the notion that nonconscious vision might be sensitive to perceptual organization and stimulus configuration through the pivotal contribution of the SC, which can enhance the processing of gestalt-like or structured stimuli over meaningless or randomly assembled ones and translate them into facilitatory motor outputs. Copyright © 2016 The Authors. Published by Elsevier

  5. Accuracy of gestalt perception of acute chest pain in predicting coronary artery disease.

    Science.gov (United States)

    das Virgens, Cláudio Marcelo Bittencourt; Lemos, Laudenor; Noya-Rabelo, Márcia; Carvalhal, Manuela Campelo; Cerqueira Junior, Antônio Maurício Dos Santos; Lopes, Fernanda Oliveira de Andrade; de Sá, Nicole Cruz; Suerdieck, Jéssica Gonzalez; de Souza, Thiago Menezes Barbosa; Correia, Vitor Calixto de Almeida; Sodré, Gabriella Sant'Ana; da Silva, André Barcelos; Alexandre, Felipe Kalil Beirão; Ferreira, Felipe Rodrigues Marques; Correia, Luís Cláudio Lemos

    2017-03-26

    To test accuracy and reproducibility of gestalt to predict obstructive coronary artery disease (CAD) in patients with acute chest pain. We studied individuals who were consecutively admitted to our Chest Pain Unit. At admission, investigators performed a standardized interview and recorded 14 chest pain features. Based on these features, a cardiologist who was blind to other clinical characteristics made unstructured judgment of CAD probability, both numerically and categorically. As the reference standard for testing the accuracy of gestalt, angiography was required to rule-in CAD, while either angiography or non-invasive test could be used to rule-out. In order to assess reproducibility, a second cardiologist did the same procedure. In a sample of 330 patients, the prevalence of obstructive CAD was 48%. Gestalt's numerical probability was associated with CAD, but the area under the curve of 0.61 (95%CI: 0.55-0.67) indicated low level of accuracy. Accordingly, categorical definition of typical chest pain had a sensitivity of 48% (95%CI: 40%-55%) and specificity of 66% (95%CI: 59%-73%), yielding a negligible positive likelihood ratio of 1.4 (95%CI: 0.65-2.0) and negative likelihood ratio of 0.79 (95%CI: 0.62-1.02). Agreement between the two cardiologists was poor in the numerical classification (95% limits of agreement = -71% to 51%) and categorical definition of typical pain (Kappa = 0.29; 95%CI: 0.21-0.37). Clinical judgment based on a combination of chest pain features is neither accurate nor reproducible in predicting obstructive CAD in the acute setting.

  6. Finding the missing stimulus mismatch negativity (MMN): emitted MMN to violations of an auditory gestalt.

    Science.gov (United States)

    Salisbury, Dean F

    2012-04-01

    Deviations from repetitive auditory stimuli evoke a mismatch negativity (MMN). Counterintuitively, omissions of repetitive stimuli do not. Violations of patterns reflecting complex rules also evoke MMN. To detect a MMN to missing stimuli, we developed an auditory gestalt task using one stimulus. Groups of six pips (50 ms duration, 330 ms stimulus onset asynchrony [SOA], 400 trials), were presented with an intertrial interval (ITI) of 750 ms while subjects (n=16) watched a silent video. Occasional deviant groups had missing 4th or 6th tones (50 trials each). Missing stimuli evoked a MMN (pgestalt grouping rule. Patterned stimuli appear more sensitive to omissions and ITI than homogenous streams.

  7. Gestalt Therapy and the Therapeutic Presence of Fritz Perls: An Interview with Claudio Naranjo

    OpenAIRE

    Ramírez Calderón, Iván; Escuela de Gestalt Claudio Naranjo Transformación Humana Colombia

    2010-01-01

    Como testigo y participe de excepción en el origen y desarrollo de la Terapia Gestalt, en esta entrevista Claudio Naranjo considera las características de esta forma de terapia, y lo hace a partir de su trabajo y de su encuentro personal con el hombre y la figura terapéutica de Fritz Perls. A lo largo de la entrevista se establece la base experiencial y los elementos del cambio terapéutico, junto con la actitud terapéutica, y la concepción holística de la persona; además se destacan los con...

  8. Gestalt-Terapia e Terapia Sistêmica: o corpo em psicoterapia

    OpenAIRE

    Marília Toscano de Araujo Gurgel

    2008-01-01

    Este trabalho demonstra a contribuição da abordagem corporal da Gestalt-Terapia para a Terapia Familiar Sistêmica. O método utilizado foi a gravação de uma oficina de corpo estruturada em saberes das duas abordagens. A oficina proporcionou, a cada participante, maior qualidade de atenção, presença, contato e criatividade, uma forma mais integrada de construir sua identidade. O entrecruzamento das duas abordagens trouxe às pessoas maior consciência de quem são e como são no "mundo", ajudando-a...

  9. The stability of four kinds of perceptual erros on the Bender-Gestalt.

    Science.gov (United States)

    Engin, A W; Wallbrown, F H

    1976-09-01

    The test-retest reliability of the Bender-Gestalt Test was investigated for 157 second graders from two middle-class schools. The test-retest interval ranged from 11 days through 15 days. Testing was conducted in accordance with the Koppitz procedure, but errors of distortion, rotation, integration, and preservation were determined separately. The total time required to reproduce the designs were also recorded. The reliability estimate for the Koppitz score was generally satisfactory, but the estimates obtained for the four separate error categories and total working time were substantially smaller.

  10. Comparison of the Developmental Test of Visual-Motor Integration and the Bender-Gestalt test.

    Science.gov (United States)

    Brown, M J

    1977-12-01

    The Developmental Test of Visual-motor Integration (Beery) and the Bender-Gestalt test (Bender) were administered to 44 second-grade children. Developmental age scores (Koppitz scoring) and age equivalents (Beery) were compared. The correlation of .43 between Bender (Koppitz scoring) and Beery scores was moderate but statistically significant. A t test for dependent groups indicated a significant difference between the means on the Bender and Beery tests. These results confirm that neither test should be utilized as the sole indicator of visual-motor perception.

  11. Fenomenologia do onírico: a gestalt-terapia e a daseinsanálise

    Directory of Open Access Journals (Sweden)

    Ívena Pérola do Amaral Santos

    Full Text Available O texto apresenta a gestalt-terapia e a daseinsanálise enquanto abordagens representativas no trabalho clínico com o sonhar humano, tendo como base o método fenomenológico. Traz os conceitos teóricos e as aplicações práticas propostas por ambas. Por fim, traz uma análise das convergências e divergências entre as duas teorias, estabelecendo-se suas distinções e contribuições.

  12. Gestalt Therapy Applied: A Case Study with an Inpatient Diagnosed with Substance Use and Bipolar Disorders.

    Science.gov (United States)

    Aiach Dominitz, Valerie

    2017-01-01

    The aim of the present paper is to open the discourse regarding the unmet needs of specific patients, especially those with substance use disorder and/or personality disorder where 'multimorbidities', and/or 'overdiagnosis' and/or 'diagnosis overlap' are frequent. An additional aim is to review the main therapeutic purpose and concepts of Gestalt therapy which might be appropriate in the treatment of these patients often characterized by their difficulties in being aware and in contact in the 'here and now'. I first start with an overview of Gestalt therapy concepts. Then, I illustrate Gestalt's 'here and now' and awareness concepts applied during 18 sessions with an inpatient diagnosed with substance use and bipolar disorders. In addition, the patient had to face an open criminal charge, was regarded as having an antisocial personality disorder and argued suffering from post-traumatic stress disorder. After this two-month therapy period, the patient entered for the first time a daily rehabilitation program in the community, where he was doing well (this after a few prior hospitalizations). The awareness development in the 'here and now' through which different contact styles and cycles of experiences are experienced is a process that allowed the patient to start experiencing contact with himself, his true needs and his environment. This contributed to his well-being improvement, led and supported his rehabilitation and reinsertion within the society and decrease his relapses, either with drugs or criminal activities. Copyright © 2016 John Wiley & Sons, Ltd. People with substance use disorder (where 'multimorbidities', 'overdiagnosis' or 'diagnosis overlap' are frequent), people with personality disorder(s) or people who have difficulties in defining what really disturbs them are the same people who could benefit of GT encouraging awareness and contact development in the 'here and now'. Gestalt therapy should not be regarded as a practitioner's toolbox but as a

  13. Fenomenologia do onírico: a gestalt-terapia e a daseinsanálise

    Directory of Open Access Journals (Sweden)

    Ívena Pérola do Amaral Santos

    Full Text Available O texto apresenta a gestalt-terapia e a daseinsanálise enquanto abordagens representativas no trabalho clínico com o sonhar humano, tendo como base o método fenomenológico. Traz os conceitos teóricos e as aplicações práticas propostas por ambas. Por fim, traz uma análise das convergências e divergências entre as duas teorias, estabelecendo-se suas distinções e contribuições.

  14. Fenomenologia do onírico: a gestalt-terapia e a daseinsanálise

    OpenAIRE

    Ívena Pérola do Amaral Santos

    2004-01-01

    O texto apresenta a gestalt-terapia e a daseinsanálise enquanto abordagens representativas no trabalho clínico com o sonhar humano, tendo como base o método fenomenológico. Traz os conceitos teóricos e as aplicações práticas propostas por ambas. Por fim, traz uma análise das convergências e divergências entre as duas teorias, estabelecendo-se suas distinções e contribuições.

  15. Molecular Mechanisms of Metastasis Suppression in Human Breast Cancer

    Science.gov (United States)

    2000-07-01

    and breast carcinoma metastasis, Wake Forest University Cancer Center, July 28 Molecular mechanisms controlling melanoma and breast carcinoma...Bowman Show, August 17 Molecular regulation of melanoma and breast carcinoma metastasis, Wake Forest University Cancer Center, July 28 Molecular...Institute, April 20, Pathology ofNeoplasia Cumberland Unit, American Cancer Society, April 19; Breast Cancer Research Ministerio de Sanidad y

  16. A second mechanism of increase of cerebellar hypermetria in humans

    Science.gov (United States)

    Manto, Mario-Ubaldo; Bosse, Pierre

    2003-01-01

    So far, there is only one procedure known to increase hypermetria in cerebellar patients. Facing an increased inertia of the moving limb, patients presenting a lesion of the lateral cerebellum are able to increase appropriately the intensity of the agonist electromyographic (EMG) activity (the launching force), but are unable to adapt the intensity of the antagonist activity (the braking force). As a result, hypermetria is larger when the inertial load is artificially increased. Recent studies have demonstrated that hyperventilation increases hypermetria in patients presenting a spinocerebellar ataxia type 6 (SCA 6), a disorder associated with polyglutamine expansions in the α1A-voltage-dependent calcium channel. The mechanism of this increase of hypermetria has not been identified so far. In the present work, we combined kinematic, EMG and transcranial Doppler studies to understand the effects of hyperventilation on fast goal-directed movements in patients presenting a SCA 6. Both in the normal mechanical state and after increasing the inertial load of the moving hand, hyperventilation induced an increase of hypermetria. Hyperventilation increased the delay of the onset latency of the antagonist EMG activity and decreased the rate of rise of both the agonist and the antagonist EMG activities. Hyperventilation induced a marked decrease in cerebral blood flow velocities. The mechanism of this provocative test is original and is distinct from the mechanism of the load-induced increase of hypermetria. PMID:12588903

  17. Dynamic Simulation and Analysis of Human Walking Mechanism

    Science.gov (United States)

    Azahari, Athirah; Siswanto, W. A.; Ngali, M. Z.; Salleh, S. Md.; Yusup, Eliza M.

    2017-01-01

    Behaviour such as gait or posture may affect a person with the physiological condition during daily activities. The characteristic of human gait cycle phase is one of the important parameter which used to described the human movement whether it is in normal gait or abnormal gait. This research investigates four types of crouch walking (upright, interpolated, crouched and severe) by simulation approach. The assessment are conducting by looking the parameters of hamstring muscle joint, knee joint and ankle joint. The analysis results show that based on gait analysis approach, the crouch walking have a weak pattern of walking and postures. Short hamstring and knee joint is the most influence factor contributing to the crouch walking due to excessive hip flexion that typically accompanies knee flexion.

  18. Abnormalities in human pluripotent cells due to reprogramming mechanisms.

    Science.gov (United States)

    Ma, Hong; Morey, Robert; O'Neil, Ryan C; He, Yupeng; Daughtry, Brittany; Schultz, Matthew D; Hariharan, Manoj; Nery, Joseph R; Castanon, Rosa; Sabatini, Karen; Thiagarajan, Rathi D; Tachibana, Masahito; Kang, Eunju; Tippner-Hedges, Rebecca; Ahmed, Riffat; Gutierrez, Nuria Marti; Van Dyken, Crystal; Polat, Alim; Sugawara, Atsushi; Sparman, Michelle; Gokhale, Sumita; Amato, Paula; Wolf, Don P; Ecker, Joseph R; Laurent, Louise C; Mitalipov, Shoukhrat

    2014-07-10

    Human pluripotent stem cells hold potential for regenerative medicine, but available cell types have significant limitations. Although embryonic stem cells (ES cells) from in vitro fertilized embryos (IVF ES cells) represent the 'gold standard', they are allogeneic to patients. Autologous induced pluripotent stem cells (iPS cells) are prone to epigenetic and transcriptional aberrations. To determine whether such abnormalities are intrinsic to somatic cell reprogramming or secondary to the reprogramming method, genetically matched sets of human IVF ES cells, iPS cells and nuclear transfer ES cells (NT ES cells) derived by somatic cell nuclear transfer (SCNT) were subjected to genome-wide analyses. Both NT ES cells and iPS cells derived from the same somatic cells contained comparable numbers of de novo copy number variations. In contrast, DNA methylation and transcriptome profiles of NT ES cells corresponded closely to those of IVF ES cells, whereas iPS cells differed and retained residual DNA methylation patterns typical of parental somatic cells. Thus, human somatic cells can be faithfully reprogrammed to pluripotency by SCNT and are therefore ideal for cell replacement therapies.

  19. Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans

    Directory of Open Access Journals (Sweden)

    Siti W. Mohd-Zin

    2017-01-01

    Full Text Available Spina bifida is among the phenotypes of the larger condition known as neural tube defects (NTDs. It is the most common central nervous system malformation compatible with life and the second leading cause of birth defects after congenital heart defects. In this review paper, we define spina bifida and discuss the phenotypes seen in humans as described by both surgeons and embryologists in order to compare and ultimately contrast it to the leading animal model, the mouse. Our understanding of spina bifida is currently limited to the observations we make in mouse models, which reflect complete or targeted knockouts of genes, which perturb the whole gene(s without taking into account the issue of haploinsufficiency, which is most prominent in the human spina bifida condition. We thus conclude that the need to study spina bifida in all its forms, both aperta and occulta, is more indicative of the spina bifida in surviving humans and that the measure of deterioration arising from caudal neural tube defects, more commonly known as spina bifida, must be determined by the level of the lesion both in mouse and in man.

  20. Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans.

    Science.gov (United States)

    Mohd-Zin, Siti W; Marwan, Ahmed I; Abou Chaar, Mohamad K; Ahmad-Annuar, Azlina; Abdul-Aziz, Noraishah M

    2017-01-01

    Spina bifida is among the phenotypes of the larger condition known as neural tube defects (NTDs). It is the most common central nervous system malformation compatible with life and the second leading cause of birth defects after congenital heart defects. In this review paper, we define spina bifida and discuss the phenotypes seen in humans as described by both surgeons and embryologists in order to compare and ultimately contrast it to the leading animal model, the mouse. Our understanding of spina bifida is currently limited to the observations we make in mouse models, which reflect complete or targeted knockouts of genes, which perturb the whole gene(s) without taking into account the issue of haploinsufficiency, which is most prominent in the human spina bifida condition. We thus conclude that the need to study spina bifida in all its forms, both aperta and occulta, is more indicative of the spina bifida in surviving humans and that the measure of deterioration arising from caudal neural tube defects, more commonly known as spina bifida, must be determined by the level of the lesion both in mouse and in man.

  1. Human Tuberculosis I. Epidemiology, Diagnosis and Pathogenetic Mechanisms.

    Science.gov (United States)

    Sgaragli, Giampietro; Frosini, Maria

    2016-01-01

    Mycobacterium tuberculosis (M. tuberculosis), an almost genetically monomorphic pathogen is a human parasite, transmitted mostly by humans and causes tuberculosis (TB). TB is firmly associated to poverty, although lack of proper nutrition and lowered immune status are contributing factors for disease development. TB remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent and is responsible for nearly 1.5 million deaths annually. Some steps of the progress of our knowledge of M. tuberculosis physiology and its interactions with human beings, are reviewed here. This progress has provided fertile ground for improving diagnosis and cure of TB infection. For TB diagnostics laboratories in high-burden countries, primary isolation is the first step before performing drug susceptibility testing (DST) of M. tuberculosis. IGRA (interferon-γ release assay)-based tests for diagnosis of active TB are sufficiently fast, specific and sensitive to allow to contain infection and distinguish among latent TB infection and BCG vaccination individuals from those who have clinically resolved M. tuberculosis infection after anti-TB treatment.

  2. Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans

    Science.gov (United States)

    Abou Chaar, Mohamad K.; Ahmad-Annuar, Azlina

    2017-01-01

    Spina bifida is among the phenotypes of the larger condition known as neural tube defects (NTDs). It is the most common central nervous system malformation compatible with life and the second leading cause of birth defects after congenital heart defects. In this review paper, we define spina bifida and discuss the phenotypes seen in humans as described by both surgeons and embryologists in order to compare and ultimately contrast it to the leading animal model, the mouse. Our understanding of spina bifida is currently limited to the observations we make in mouse models, which reflect complete or targeted knockouts of genes, which perturb the whole gene(s) without taking into account the issue of haploinsufficiency, which is most prominent in the human spina bifida condition. We thus conclude that the need to study spina bifida in all its forms, both aperta and occulta, is more indicative of the spina bifida in surviving humans and that the measure of deterioration arising from caudal neural tube defects, more commonly known as spina bifida, must be determined by the level of the lesion both in mouse and in man. PMID:28286691

  3. Mechanisms and genes in human strial presbycusis from animal models.

    Science.gov (United States)

    Ohlemiller, Kevin K

    2009-06-24

    Schuknecht proposed a discrete form of presbycusis in which hearing loss results principally from degeneration of cochlear stria vascularis and decline of the endocochlear potential (EP). This form was asserted to be genetically linked, and to arise independently from age-related pathology of either the organ of Corti or cochlear neurons. Although extensive strial degeneration in humans coincides with hearing loss, EPs have never been measured in humans, and age-related EP reduction has never been verified. No human genes that promote strial presbycusis have been identified, nor is its pathophysiology well understood. Effective application of animal models to this issue requires models demonstrating EP decline, and preferably, genetically distinct strains that vary in patterns of EP decline and its cellular correlates. Until recently, only two models, Mongolian gerbils and Tyrp1(B-lt) mice, were known to undergo age-associated EP reduction. Detailed studies of seven inbred mouse strains have now revealed three strains (C57BL/6J, B6.CAST-Cdh23(CAST), CBA/J) showing essentially no EP decline with age, and four strains ranging from modest to severe EP reduction (C57BL/6-Tyr(c-2J), BALB/cJ, CBA/CaJ, NOD.NON-H2(nbl)/LtJ). Collectively, animal models support five basic principles regarding a strial form of presbycusis: 1) Progressive EP decline from initially normal levels as a defining characteristic; 2) Non-universality, not all age-associated hearing loss involves EP decline; 3) A clear genetic basis; 4) Modulation by environment or stochastic events; and 5) Independent strial, organ of Corti, and neural pathology. Shared features between human strial presbycusis, gerbils, and BALB/cJ and C57BL/6-Tyr(c-2J) mice further suggest this condition frequently begins with strial marginal cell dysfunction and loss. By contrast, NOD.NON-H2(nbl) mice may model a sequence more closely associated with strial microvascular disease. Additional studies of these and other inbred mouse

  4. Hereditary hearing loss: from human mutation to mechanism.

    Science.gov (United States)

    Lenz, Danielle R; Avraham, Karen B

    2011-11-01

    The genetic heterogeneity of hereditary hearing loss is thus far represented by hundreds of genes encoding a large variety of proteins. Mutations in these genes have been discovered for patients with different modes of inheritance and types of hearing loss, ranging from syndromic to non-syndromic and mild to profound. In many cases, the mechanisms whereby the mutations lead to hearing loss have been partly elucidated using cell culture systems and mouse and other animal models. The discovery of the genes has completely changed the practice of genetic counseling in this area, providing potential diagnosis in many cases that can be coupled with clinical phenotypes and offer predictive information for families. In this review we provide three examples of gene discovery in families with hereditary hearing loss, all associated with elucidation of some of the mechanisms leading to hair cell degeneration and pathology of deafness.

  5. Recent Advances in Computational Mechanics of the Human Knee Joint

    Directory of Open Access Journals (Sweden)

    M. Kazemi

    2013-01-01

    Full Text Available Computational mechanics has been advanced in every area of orthopedic biomechanics. The objective of this paper is to provide a general review of the computational models used in the analysis of the mechanical function of the knee joint in different loading and pathological conditions. Major review articles published in related areas are summarized first. The constitutive models for soft tissues of the knee are briefly discussed to facilitate understanding the joint modeling. A detailed review of the tibiofemoral joint models is presented thereafter. The geometry reconstruction procedures as well as some critical issues in finite element modeling are also discussed. Computational modeling can be a reliable and effective method for the study of mechanical behavior of the knee joint, if the model is constructed correctly. Single-phase material models have been used to predict the instantaneous load response for the healthy knees and repaired joints, such as total and partial meniscectomies, ACL and PCL reconstructions, and joint replacements. Recently, poromechanical models accounting for fluid pressurization in soft tissues have been proposed to study the viscoelastic response of the healthy and impaired knee joints. While the constitutive modeling has been considerably advanced at the tissue level, many challenges still exist in applying a good material model to three-dimensional joint simulations. A complete model validation at the joint level seems impossible presently, because only simple data can be obtained experimentally. Therefore, model validation may be concentrated on the constitutive laws using multiple mechanical tests of the tissues. Extensive model verifications at the joint level are still crucial for the accuracy of the modeling.

  6. Recent advances in computational mechanics of the human knee joint.

    Science.gov (United States)

    Kazemi, M; Dabiri, Y; Li, L P

    2013-01-01

    Computational mechanics has been advanced in every area of orthopedic biomechanics. The objective of this paper is to provide a general review of the computational models used in the analysis of the mechanical function of the knee joint in different loading and pathological conditions. Major review articles published in related areas are summarized first. The constitutive models for soft tissues of the knee are briefly discussed to facilitate understanding the joint modeling. A detailed review of the tibiofemoral joint models is presented thereafter. The geometry reconstruction procedures as well as some critical issues in finite element modeling are also discussed. Computational modeling can be a reliable and effective method for the study of mechanical behavior of the knee joint, if the model is constructed correctly. Single-phase material models have been used to predict the instantaneous load response for the healthy knees and repaired joints, such as total and partial meniscectomies, ACL and PCL reconstructions, and joint replacements. Recently, poromechanical models accounting for fluid pressurization in soft tissues have been proposed to study the viscoelastic response of the healthy and impaired knee joints. While the constitutive modeling has been considerably advanced at the tissue level, many challenges still exist in applying a good material model to three-dimensional joint simulations. A complete model validation at the joint level seems impossible presently, because only simple data can be obtained experimentally. Therefore, model validation may be concentrated on the constitutive laws using multiple mechanical tests of the tissues. Extensive model verifications at the joint level are still crucial for the accuracy of the modeling.

  7. Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance.

    Science.gov (United States)

    Gault, Judith; Sarin, Hemant; Awadallah, Nabil A; Shenkar, Robert; Awad, Issam A

    2004-07-01

    Cerebrovascular malformations affect more than 3% of the population, exposing them to a lifetime risk of hemorrhagic stroke, seizures, and focal neurological deficits. Cerebral cavernous malformations (CCMs) exhibit an immature vessel wall, a brittle hemorrhagic tendency, and epileptogenesis, whereas arteriovenous malformations (AVMs) lack capillary beds and manifest apoplectic bleeding under high-flow conditions. There are also more benign venous anomalies, capillary malformations, and lesions with mixed and transitional features. Advances have been made toward understanding the natural history, radiological and pathological correlates, and clinical management. Yet, mechanisms of lesion genesis and clinical manifestations remain largely unknown, and the clinical behavior in individual patients is highly unpredictable. Lesion pathogenesis likely involves abnormal assembly or maintenance of blood vessels, resulting in dysmorphic vessel phenotypes. Familial CCM disease is in part caused by mutations in a cytoskeletal-related protein that is likely integral to interendothelial cell connectivity and maturation of the vascular wall. Rare familial forms of AVM disease have been correlated with two different transforming growth factor-beta receptor components, possibly causing disturbance in signaling during vascular assembly. Relevance of these mechanisms to the more common and otherwise identical sporadic CCM and AVM lesions is being explored. In this report, basic mechanisms of vasculogenesis and angiogenesis and how they possibly relate to the common cerebrovascular malformation lesions are reviewed. Novel concepts are discussed related to the cellular, molecular, and genetic substrates in CCM and AVM as well as to how this knowledge can be applied to predict, explain, and possibly modify clinical disease manifestations.

  8. Enzymes approved for human therapy: indications, mechanisms and adverse effects.

    Science.gov (United States)

    Baldo, Brian A

    2015-02-01

    Research and drug developments fostered under orphan drug product development programs have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of rare disorders. The introduction and regulatory approval of 20 different recombinant enzymes has enabled, often for the first time, effective enzyme-replacement therapy for some lysosomal storage disorders, including Gaucher (imiglucerase, taliglucerase, and velaglucerase), Fabry (agalsidase alfa and beta), and Pompe (alglucosidase alfa) diseases and mucopolysaccharidoses I (laronidase), II (idursulfase), IVA (elosulfase), and VI (galsulfase). Approved recombinant enzymes are also now used as therapy for myocardial infarction (alteplase, reteplase, and tenecteplase), cystic fibrosis (dornase alfa), chronic gout (pegloticase), tumor lysis syndrome (rasburicase), leukemia (L-asparaginase), some collagen-based disorders such as Dupuytren's contracture (collagenase), severe combined immunodeficiency disease (pegademase bovine), detoxification of methotrexate (glucarpidase), and vitreomacular adhesion (ocriplasmin). The development of these efficacious and safe enzyme-based therapies has occurred hand in hand with some remarkable advances in the preparation of the often specifically designed recombinant enzymes; the manufacturing expertise necessary for commercial production; our understanding of underlying mechanisms operative in the different diseases; and the mechanisms of action of the relevant recombinant enzymes. Together with information on these mechanisms, safety findings recorded so far on the various adverse events and problems of immunogenicity of the recombinant enzymes used for therapy are presented.

  9. A Combined Softening and Hardening Mechanism for Low Frequency Human Motion Energy Harvesting Application

    Directory of Open Access Journals (Sweden)

    Khalis Suhaimi

    2014-01-01

    Full Text Available This paper concerns the mechanism for harvesting energy from human body motion. The vibration signal from human body motion during walking and jogging was first measured using 3-axes vibration recorder placed at various places on the human body. The measured signal was then processed using Fourier series to investigate its frequency content. A mechanism was proposed to harvest the energy from the low frequency-low amplitude human motion. This mechanism consists of the combined nonlinear hardening and softening mechanism which was aimed at widening the bandwidth as well as amplifying the low human motion frequency. This was realized by using a translation-to-rotary mechanism which converts the translation motion of the human motion into the rotational motion. The nonlinearity in the system was realized by introducing a winding spring stiffness and the magnetic stiffness. Quasi-static and dynamic measurement were conducted to investigate the performance of the mechanism. The results show that, with the right degree of nonlinearity, the two modes can be combined together to produce a wide flat response. For the frequency amplification, the mechanism manages to increase the frequency by around 8 times in terms of rotational speed.

  10. Neisseria meningitidis, pathogenetic mechanisms to overcome the human immune defences.

    Science.gov (United States)

    Gasparini, R; Amicizia, D; Lai, P L; Panatto, D

    2012-06-01

    Neisseria meningitidis is hosted only by humans and colonizes the nasopharynx; it survives in the human body by reaching an equilibrium with its exclusive host. Indeed, while cases of invasive disease are rare, the number of asymptomatic Neisseria meningitides carriers is far higher. The aim of this paper is to summarize the current knowledge of survival strategies of Neisseria meningitides against the human immune defences. Neisseria meningitidis possesses a variety of adaptive characteristics which enable it to avoid being killed by the immune system, such as the capsule, the lipopolysaccharide, groups of proteins that block the action of the antimicrobial proteins (AMP), proteins that inhibit the complement system, and components that prevent both the maturation and the perfect functioning of phagocytes. The main means of adhesion of Neisseria meningitides to the host cells are Pili, constituted by several proteins of whom the most important is Pilin E. Opacity-associated proteins (Opa) and (Opc) are two proteins that make an important contribution to the process of adhesion to the cell. Porins A and B contribute to neisserial adhesion and penetration into the cells, and also inhibit the complement system. Factor H binding protein (fhbp) binds factor H, allowing the bacteria to survive in the blood. Neisserial adhesin A (NadA) is a minor adhesin that is expressed by 50% of the pathogenic strains. NadA is known to be involved in cell adhesion and invasion and in the induction of proinflammatory cytokines. Neisserial heparin binding antigen (NHBA) binds heparin, thus increasing the resistance of the bacterium in the serum.

  11. Aquaporin water channels: molecular mechanisms for human diseases.

    Science.gov (United States)

    Agre, Peter; Kozono, David

    2003-11-27

    Although water is the major component of all biological fluids, the molecular pathways for water transport across cell membranes eluded identification until the discovery of the aquaporin family of water channels. The atomic structure of mammalian AQP1 illustrates how this family of proteins is freely permeated by water but not protons (hydronium ions, H3O+). Definition of the subcellular sites of expression predicted their physiological functions and potential clinical disorders. Analysis of several human disease states has confirmed that aquaporins are involved in multiple different illnesses including abnormalities of kidney function, loss of vision, onset of brain edema, starvation, and arsenic toxicity.

  12. Mechanism of mast cell adhesion to human tenocytes in vitro.

    Science.gov (United States)

    Behzad, Hayedeh; Tsai, Shu-Huei; Nassab, Paulina; Mousavizadeh, Rouhollah; McCormack, Robert G; Scott, Alex

    2015-01-01

    Mast cells and fibroblasts are two key players involved in many fibrotic and degenerative disorders. In the present study we examined the nature of binding interactions between human mast cells and tendon fibroblasts (tenocytes). In the mast cell-fibroblast co-culture model, mast cells were shown to spontaneously bind to tenocytes, in a process that was partially mediated by α5β1 integrin receptors. The same receptors on mast cells significantly mediated binding of these cells to tissue culture plates in the presence of tenocyte-conditioned media; the tenocyte-derived fibronectin in the media was shown to also play a major role in these binding activities. Upon binding to tenocytes or tissue culture plates, mast cells acquired an elongated phenotype, which was dependent on α5β1 integrin and tenocyte fibronectin. Additionally, tenocyte-derived fibronectin significantly enhanced mRNA expression of the adhesion molecule, THY1, by mast cells. Our data suggests that α5β1 integrin mediates binding of mast cells to human tenocyte and to tenocyte-derived ECM proteins, in particular fibronectin.

  13. Neural mechanisms of perceptual grouping in human visual cortex

    Institute of Scientific and Technical Information of China (English)

    MAO Lihua; HAN Shihui; GUO Chunyan; JIANG Yi

    2004-01-01

    The current work examined neural substrates of perceptual grouping in human visual cortex using event-related potential (ERP) recording. Stimulus arrays consisted of local elements that were either evenly spaced (uniform stimuli) or grouped into columns or rows by proximity or color similarity (grouping stimuli). High-density ERPs were recorded while subjects identified orientations of perceptual groups in stimulus arrays that were presented randomly in one of the four quadrants of the visual field. Both uniform and grouping stimulus arrays elicited an early ERP component (C1), which peaked at about 70 ms after stimulus onset and changed its polarity as a function of stimulated elevations. Dipole modeling based on realistic- head boundary-element models revealed generators of the C1 component in the calcarine cortex. The C1 was modulated by perceptual grouping of local elements based on proximity, and this grouping effect was stronger in the upper than in the lower visual field. The findings provide ERP evidence for the engagement of human primary visual cortex in the early stage of perceptual grouping.

  14. Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Mostafalou, Sara; Abdollahi, Mohammad, E-mail: Mohammad.Abdollahi@UToronto.Ca

    2013-04-15

    Along with the wide use of pesticides in the world, the concerns over their health impacts are rapidly growing. There is a huge body of evidence on the relation between exposure to pesticides and elevated rate of chronic diseases such as different types of cancers, diabetes, neurodegenerative disorders like Parkinson, Alzheimer, and amyotrophic lateral sclerosis (ALS), birth defects, and reproductive disorders. There is also circumstantial evidence on the association of exposure to pesticides with some other chronic diseases like respiratory problems, particularly asthma and chronic obstructive pulmonary disease (COPD), cardiovascular disease such as atherosclerosis and coronary artery disease, chronic nephropathies, autoimmune diseases like systemic lupus erythematous and rheumatoid arthritis, chronic fatigue syndrome, and aging. The common feature of chronic disorders is a disturbance in cellular homeostasis, which can be induced via pesticides' primary action like perturbation of ion channels, enzymes, receptors, etc., or can as well be mediated via pathways other than the main mechanism. In this review, we present the highlighted evidence on the association of pesticide's exposure with the incidence of chronic diseases and introduce genetic damages, epigenetic modifications, endocrine disruption, mitochondrial dysfunction, oxidative stress, endoplasmic reticulum stress and unfolded protein response (UPR), impairment of ubiquitin proteasome system, and defective autophagy as the effective mechanisms of action. - Highlights: ► There is a link between exposure to pesticides and incidence of chronic diseases. ► Genotoxicity and proteotoxicity are two main involved mechanisms. ► Epigenetic knowledge may help diagnose the relationships. ► Efficient policies on safe use of pesticides should be set up.

  15. Human and bovine spinal disc mechanics subsequent to trypsin injection

    Directory of Open Access Journals (Sweden)

    Jeremy Alsup

    2017-10-01

    The Translational Potential of this Article: Preclinical testing of novel spinal devices is essential to the design validation and regulatory processes, but current testing techniques rely on cadaveric testing of primarily older spines with essentially random amounts of disc degeneration. The present work investigates the viability of using trypsin injections to create a more uniform preclinical model of disc degeneration from a mechanics perspective, for the purpose of testing spinal devices. Such a model would facilitate translation of new spinal technologies to clinical practice.

  16. The human rhinovirus: human-pathological impact, mechanisms of antirhinoviral agents, and strategies for their discovery.

    Science.gov (United States)

    Rollinger, Judith M; Schmidtke, Michaela

    2011-01-01

    As the major etiological agent of the common cold, human rhinoviruses (HRV) cause millions of lost working and school days annually. Moreover, clinical studies proved an association between harmless upper respiratory tract infections and more severe diseases e.g. sinusitis, asthma, and chronic obstructive pulmonary disease. Both the medicinal and socio-economic impact of HRV infections and the lack of antiviral drugs substantiate the need for intensive antiviral research. A common structural feature of the approximately 100 HRV serotypes is the icosahedrally shaped capsid formed by 60 identical copies of viral capsid proteins VP1-4. The capsid protects the single-stranded, positive sense RNA genome of about 7,400 bases in length. Both structural as well as nonstructural proteins produced during the viral life cycle have been identified as potential targets for blocking viral replication at the step of attachment, entry, uncoating, RNA and protein synthesis by synthetic or natural compounds. Moreover, interferon and phytoceuticals were shown to protect host cells. Most of the known inhibitors of HRV replication were discovered as a result of empirical or semi-empirical screening in cell culture. Structure-activity relationship studies are used for hit optimization and lead structure discovery. The increasing structural insight and molecular understanding of viral proteins on the one hand and the advent of innovative computer-assisted technologies on the other hand have facilitated a rationalized access for the discovery of small chemical entities with antirhinoviral (anti-HRV) activity. This review will (i) summarize existing structural knowledge about HRV, (ii) focus on mechanisms of anti-HRV agents from synthetic and natural origin, and (iii) demonstrate strategies for efficient lead structure discovery.

  17. Mechanical properties of an artificial vascularized human skin

    Science.gov (United States)

    Passot, A.; Cabodevila, G.

    2011-05-01

    In order to make blood sample tests an artificial skin similar to that of the baby's heel is modeled and realized. The most superficial bloodstream and the two main layers of the skin -epidermis and dermis- have to be recreated. Studies and capillaroscopies of the baby's heel give characteristics of these layers and the bloodstream. The skin is viscohyperelastic, but the choice of materials that will be used is based on the Young's modulus. The epidermis layer is based on a stronger less adhesive silicon rubber Elastosil. The dermis layer is composed of a mixture based on a very soft sticky silicon rubber Silgel and Sylgard. The mixture of Silgel with 5% Sylgard has an elastic modulus of 48 kPa which is similar to that of the dermis. The artificial skin is an assembly of several layers including a layer of Sylgard that is structured by a mold representing the capillary network and adapted to manufacturing processes in a clean room. Each layer is deposited by spin coating and is combined with the other through adhesion. Mechanical tests such as tension are performed to verify the mechanical properties of the artificial skin.

  18. Pesticides and human chronic diseases: evidences, mechanisms, and perspectives.

    Science.gov (United States)

    Mostafalou, Sara; Abdollahi, Mohammad

    2013-04-15

    Along with the wide use of pesticides in the world, the concerns over their health impacts are rapidly growing. There is a huge body of evidence on the relation between exposure to pesticides and elevated rate of chronic diseases such as different types of cancers, diabetes, neurodegenerative disorders like Parkinson, Alzheimer, and amyotrophic lateral sclerosis (ALS), birth defects, and reproductive disorders. There is also circumstantial evidence on the association of exposure to pesticides with some other chronic diseases like respiratory problems, particularly asthma and chronic obstructive pulmonary disease (COPD), cardiovascular disease such as atherosclerosis and coronary artery disease, chronic nephropathies, autoimmune diseases like systemic lupus erythematous and rheumatoid arthritis, chronic fatigue syndrome, and aging. The common feature of chronic disorders is a disturbance in cellular homeostasis, which can be induced via pesticides' primary action like perturbation of ion channels, enzymes, receptors, etc., or can as well be mediated via pathways other than the main mechanism. In this review, we present the highlighted evidence on the association of pesticide's exposure with the incidence of chronic diseases and introduce genetic damages, epigenetic modifications, endocrine disruption, mitochondrial dysfunction, oxidative stress, endoplasmic reticulum stress and unfolded protein response (UPR), impairment of ubiquitin proteasome system, and defective autophagy as the effective mechanisms of action. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Some normative data on the Bender Gestalt test performance of Iranian children.

    Science.gov (United States)

    Yousefi, F; Shahim, S; Razavieh, A; Mehryar, A H; Hosseini, A A; Alborzi, S

    1992-11-01

    The Bender Gestalt test of visuomotor coordination was applied to a sample of Iranian children (N = 1,600) aged between 6.0 years and 10 years and 11 months attending grades 1 through 5 of 16 public primary schools in Shiraz city, southern Iran. The administration of the test and its scoring followed the standard procedures recommended by Koppitz. The reliability of the test in its new context was investigated through readministering it to a group of 60 children after four weeks, the r being .77. The validity of the test was established by comparing scores of children at different age levels and by correlating test results with marks obtained in two sets of examinations, results of Goodenough Harris Draw-A-Person Test and indices of parental education and occupation. The results are mostly in the expected direction and indicate that the Bender Gestalt test may be used as a simple measure of cognitive-intellectual development in Iran. Observed differences between Iranian norms and those of Koppitz (1963, 1975) for American children are briefly discussed and explained.

  20. Arnheim's Gestalt Theory of Visual Balance: Examining the Compositional Structure of Art Photographs and Abstract Images

    Directory of Open Access Journals (Sweden)

    I C McManus

    2011-08-01

    Full Text Available In Art and Visual Perception, Rudolf Arnheim, following on from Denman Ross's A Theory of Pure Design, proposed a Gestalt theory of visual composition. The current paper assesses a physicalist interpretation of Arnheim's theory, calculating an image's centre of mass (CoM. Three types of data are used: a large, representative collection of art photographs of recognised quality; croppings by experts and non-experts of photographs; and Ross and Arnheim's procedure of placing a frame around objects such as Arnheim's two black disks. Compared with control images, the CoM of art photographs was closer to an axis (horizontal, vertical, or diagonal, as was the case for photographic croppings. However, stronger, within-image, paired comparison studies, comparing art photographs with the CoM moved on or off an axis (the “gamma-ramp study”, or comparing adjacent croppings on or off an axis (the “spider-web study”, showed no support for the Arnheim-Ross theory. Finally, studies moving a frame around two disks, of different size, greyness, or background, did not support Arnheim's Gestalt theory. Although the detailed results did not support the Arnheim-Ross theory, several significant results were found which clearly require explanation by any adequate theory of the aesthetics of visual composition.

  1. Gestalt grouping effects on tactile information processing: when touching hands override spatial proximity.

    Science.gov (United States)

    Frings, Christian; Spence, Charles

    2013-04-01

    Using a tactile variant of the negative-priming paradigm, we analyzed the influence of Gestalt grouping on the ability of participants to ignore distracting tactile information. The distance between participants' hands, to which the target and distractor stimuli were simultaneously delivered, was varied (near/touching hands vs. hands far apart). In addition, the influence of touching hands was controlled, as participants wore gloves and their hands were blocked from vision by a cover. The magnitude of the tactile negative-priming effect was modulated by the interaction between hand separation and whether or not gloves were worn. When the hands were touching, negative priming emerged only while wearing gloves that prevented direct skin-to-skin contact. In contrast, when the separation between the participants' hands was larger, negative priming emerged only when gloves were not worn. This pattern of results is interpreted in terms of the competing influences of two interacting Gestalt principles--namely, connectedness and proximity--on the processing of tactile distractors.

  2. Stimulus size mediates Gestalt processes in object perception - evidence from simultanagnosia.

    Science.gov (United States)

    Rennig, Johannes; Karnath, Hans-Otto

    2016-08-01

    Simultanagnosia caused by posterior temporo-parietal brain damage is characterized through an inability to recognize a global Gestalt from an arrangement of single objects while perception of single objects appears widely intact. We asked whether recognition of single objects in simultanagnosia is still intact if objects are really large, i.e. if they exceed the size of a usual computer screen. Single objects were presented in three different sizes: 'regular', 'medium', and 'large'. Simultanagnosia patients demonstrated a decrease of recognition performance with increasing object size; recognition of 'large' objects was significantly impaired while perception of 'regular' sized objects was unaffected. The results argue against the traditional view of preserved recognition of single objects in simultanagnosia. They provide evidence for a more general perceptual impairment that emerges irrespective of presenting single or multiple objects, but whenever the visual system has to assemble information over larger spatial distances or other demanding viewing conditions. It appears that perception of large single objects requires intact abilities of dorsal Gestalt processing, in addition to regular functions of ventral object recognition. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Predicting and preventing peripheral intravenous cannula insertion failure in the emergency department: Clinician 'gestalt' wins again.

    Science.gov (United States)

    Rippey, James Cr; Carr, Peter J; Cooke, Marie; Higgins, Niall; Rickard, Claire M

    2016-12-01

    Failed attempts at peripheral i.v. cannula (PIVC) insertion in the ED are common. The psychological, physical and economic impact of these failures is significant. We sought to explore whether clinicians of differing experience levels can predict their own likelihood (clinician 'gestalt') of first-time cannula insertion success on any given patient. Data analyses from a prospective self-reported study assessing risk factors for first-time insertion success in a tertiary adult ED. We constructed and compared two simple theoretical clinical decision algorithms in an attempt to improve first-time PIVC insertion success rates. This best algorithm identified a subgroup of 18% of the total PIVC population at higher risk of failure. This 18% comprised 57% of all PIVC failures, and implementation would result in a relative risk reduction of PIVC failure by 31%. When applied to our sample population, an algorithm relying on clinician gestalt to identify patients at high risk of PIVC failure had the greatest potential impact. These patients would be referred to expert PIVC inserters prior to, rather than after, failed attempts. © 2016 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  4. Arnheim's Gestalt theory of visual balance: Examining the compositional structure of art photographs and abstract images.

    Science.gov (United States)

    McManus, I C; Stöver, Katharina; Kim, Do

    2011-01-01

    In Art and Visual Perception, Rudolf Arnheim, following on from Denman Ross's A Theory of Pure Design, proposed a Gestalt theory of visual composition. The current paper assesses a physicalist interpretation of Arnheim's theory, calculating an image's centre of mass (CoM). Three types of data are used: a large, representative collection of art photographs of recognised quality; croppings by experts and non-experts of photographs; and Ross and Arnheim's procedure of placing a frame around objects such as Arnheim's two black disks. Compared with control images, the CoM of art photographs was closer to an axis (horizontal, vertical, or diagonal), as was the case for photographic croppings. However, stronger, within-image, paired comparison studies, comparing art photographs with the CoM moved on or off an axis (the 'gamma-ramp study'), or comparing adjacent croppings on or off an axis (the 'spider-web study'), showed no support for the Arnheim-Ross theory. Finally, studies moving a frame around two disks, of different size, greyness, or background, did not support Arnheim's Gestalt theory. Although the detailed results did not support the Arnheim-Ross theory, several significant results were found which clearly require explanation by any adequate theory of the aesthetics of visual composition.

  5. Figure and Ground in the Visual Cortex: V2 Combines Stereoscopic Cues with Gestalt Rules

    Science.gov (United States)

    Qiu, Fangtu T.; von der Heydt, Rüdiger

    2006-01-01

    Figure-ground organization is a process by which the visual system identifies some image regions as foreground and others as background, inferring three-dimensional (3D) layout from 2D displays. A recent study reported that edge responses of neurons in area V2 are selective for side-of-figure, suggesting that figure-ground organization is encoded in the contour signals (border-ownership coding). Here we show that area V2 combines two strategies of computation, one that exploits binocular stereoscopic information for the definition of local depth order, and another that exploits the global configuration of contours (gestalt factors). These are combined in single neurons so that the ‘near’ side of the preferred 3D edge generally coincides with the preferred side-of-figure in 2D displays. Thus, area V2 represents the borders of 2D figures as edges of surfaces, as if the figures were objects in 3D space. Even in 3D displays gestalt factors influence the responses and can enhance or null the stereoscopic depth information. PMID:15996555

  6. Connectionism, parallel constraint satisfaction processes, and gestalt principles: (re) introducing cognitive dynamics to social psychology.

    Science.gov (United States)

    Read, S J; Vanman, E J; Miller, L C

    1997-01-01

    We argue that recent work in connectionist modeling, in particular the parallel constraint satisfaction processes that are central to many of these models, has great importance for understanding issues of both historical and current concern for social psychologists. We first provide a brief description of connectionist modeling, with particular emphasis on parallel constraint satisfaction processes. Second, we examine the tremendous similarities between parallel constraint satisfaction processes and the Gestalt principles that were the foundation for much of modem social psychology. We propose that parallel constraint satisfaction processes provide a computational implementation of the principles of Gestalt psychology that were central to the work of such seminal social psychologists as Asch, Festinger, Heider, and Lewin. Third, we then describe how parallel constraint satisfaction processes have been applied to three areas that were key to the beginnings of modern social psychology and remain central today: impression formation and causal reasoning, cognitive consistency (balance and cognitive dissonance), and goal-directed behavior. We conclude by discussing implications of parallel constraint satisfaction principles for a number of broader issues in social psychology, such as the dynamics of social thought and the integration of social information within the narrow time frame of social interaction.

  7. Developmental Model Using Gestalt-Play versus Cognitive-Verbal Group with Chinese Adolescents: Effects on Strengths and Adjustment Enhancement

    Science.gov (United States)

    Shen, Yih-Jiun

    2007-01-01

    This study compared the effectiveness of short-term developmental group counseling applying Gestalt-play versus cognitive-verbal approaches with Taiwanese adolescents. On a measure of behavioral and emotional strengths, teachers reported significant changes in students' overall behavioral and emotional strengths measured via total scores. Specific…

  8. A psicologia da gestalt e a ciência empírica contemporânea

    Directory of Open Access Journals (Sweden)

    Engelmann Arno

    2002-01-01

    Full Text Available Wertheimer realizou um experimento que era explicado seguindo-se fatores holísticos gestálticos, e isto há mais de noventa anos. Apesar disso, estudos recentes demonstram a vivacidade desse tipo de explicação. Basicamente, ao se observar coisas do mundo, observa-se suas formas ou melhor suas Gestalten. A seguir, pode-se dividir essas Gestalten em partes. Porém cada parte será sempre parte daquela Gestalt que lhe deu inicio e não um elemento constituinte básico. A teoria da Gestalt não é exclusivamente psicológica, como o demonstraram principalmente Wertheimer, Köhler e Koffka. Iniciou-se com um experimento sobre a visão de movimentos correspondendo a estímulos estáticos, mas continuou propondo-se inclusive, de um lado, uma Gestalt física formada da corrente elétrica gestálticas dentro de um condutor ou, de outro, uma Gestalt sociológica formada de muitos seres humanos, como o dançar de pares ao som de um samba realizado por um grupo de músicos.

  9. The Bender Gestalt and the Ravens Progressive Matrices Measures of Perceptual Behavior, Motor Behavior and Perceptual-Motor Behavior.

    Science.gov (United States)

    Roberds, Jeannette

    The scores of 79 second-grade pupils on the Ravens Colored Progressive Matrices and the Bender Gestalt were factor-analyzed using six different factor-analytic procedures. Sex, age, and vocabulary test scores were included in the analysis as marker variables. The original factor solutions were subjected to oblique transformation and the…

  10. Comparison of the Bender Gestalt Test for Both Black and White Brain-Damaged Patients Using Two Scoring Systems

    Science.gov (United States)

    Butler, Oliver T.; And Others

    1976-01-01

    This study tested for cultural bias in the Bender Visual Motor Gestalt Test. Subjects were 72 black and white patients diagnosed as either brain damaged or psychiatric. Bender protocols were scored by Pascal-Suttell and Hain systems. No race effect appeared except for the Pascal-Suttell system for which blacks scored significantly better. (Author)

  11. The Bender Visual Motor Gestalt Test: Correlations with WISC-R and Attainment Measures in a Clinic Sample.

    Science.gov (United States)

    Hamer, Ann

    1988-01-01

    Use of the Bender Visual Motor Gestalt Test in Australia was studied by comparing it with existing research, scores on the Wechsler Intelligence Scale for Children-Revised (WISC-R), and other attainment tests. Subjects were 142 children aged 7-11 years. The suitability of the instrument in Australia is discussed. (SLD)

  12. The Feasibility of a Group Bender-Gestalt Test for Preschool and Primary School-Aged Children

    Science.gov (United States)

    McCarthy, Denis P.

    1975-01-01

    Study devised and tested a method for group administration of the Bender-Gestalt Test that would be feasible for screening large groups of beginning school-age children. Results indicate that the group method of presentation can yield results as valid and reliable as the traditional individual method of administration. (Author)

  13. Comparison of the Minnesota Percepto-Diagnostic Test-Revised and Bender-Gestalt in Predicting Achievement.

    Science.gov (United States)

    Fuller, Gerald B.; Vance, Booney

    1993-01-01

    Investigated whether Minnesota Percepto-Diagnostic Test-Revised (MPD-R) or Bender-Gestalt Test (BG) would more accurately predict achievement at first-, third-, and fifth-grade levels. Administered both tests to 84 children in counterbalanced order. Results indicated that MPD-R was better predictor of achievement than BG, especially at first- and…

  14. Memory-for-Designs, Bender-Gestalt, Trail Making Test, and WISC-R Performance of Retarded and Adequate Readers

    Science.gov (United States)

    McManis, Donald L.; And Others

    1978-01-01

    Twelve reading-disabled and 12 nondisabled boys, of average intellectual ability, in Grades 3 to 6 were compared on the Memory-For-Designs, Bender-Gestalt, Trail Making Test, and the 11 subtests of the Wechsler Intelligence Scale for Children--Revised (WISC-R). (Author)

  15. The Bender Gestalt Test: A Review of Reported Research with School-Age Subjects, 1966-1977

    Science.gov (United States)

    Buckley, Pepper D.

    1978-01-01

    The past 11 years of published research investigating the use of the Bender Gestalt Test with school-age children are reviewed. Seen as a psychometric instrument, scored according to standardized procedures, this recent work does not conclusively support use of the test for prediction of school achievement or emotional disturbance. (Author)

  16. The Visual Aural Digit Span Test and Bender Gestalt Test as Predictors of Wide Range Achievement Test-Revised Scores.

    Science.gov (United States)

    Smith, Teresa C.; Smith, Billy L.

    1988-01-01

    Examined Visual Aural Digit Span Test (VADS) and Bender-Gestalt (BG) scores as predictors of Wide Range Achievement Test-Revised (WRAT-R) scores among 115 elementary school students referred for low academic achievement. Divided children into three age groups. Results suggest BG and VADS Test can be effective screening devices for young children…

  17. Gifted Children and Visual-Motor Development: A Comparison of Bender-Gestalt and VMI Test Performance.

    Science.gov (United States)

    Knoff, Howard M.; Sperling, Barbara L.

    1986-01-01

    A sample of 63 gifted elementary-school students was administered the Bender Visual-Motor Gestalt Test and the Developmental Test of Visual-Motor Integration. Group results revealed no significant differences between the two tests, that they did correlate significantly, and that younger students had advanced visual-motor development when tested…

  18. Interscorer Reliability of the Modified Version of the Bender-Gestalt Test for Preschool and Primary School Children.

    Science.gov (United States)

    Fuller, Gerald B.; Vance, Booney

    1995-01-01

    Extends the reliability research of the Qualitative Scoring System for the Modified Version of the Bender-Gestalt Test. The test was administered to 48 children, and the 48 test protocols were scored independently by two psychologists using the Qualitative Scoring System. Results indicated that the scoring system is highly reliable. (JPS)

  19. Validity of the Draw-A-Person and Bender Gestalt Tests as Measures of Impulsivity with Adolescents.

    Science.gov (United States)

    Oas, Peter

    1984-01-01

    Designated 100 psychiatrically hospitalized and 114 nonhospitalized adolescents as impulsive or nonimpulsive and compared them to determine the validity of signs of impulsivity on the Draw-A-Person and Bender Gestalt tests. Signs of impulsivity and nonimpulsivity on these tests discriminated between impulsive and nonimpulsive adolescents with…

  20. Gifted Children and Visual-Motor Development: A Comparison of Bender-Gestalt and VMI Test Performance.

    Science.gov (United States)

    Knoff, Howard M.; Sperling, Barbara L.

    1986-01-01

    A sample of 63 gifted elementary-school students was administered the Bender Visual-Motor Gestalt Test and the Developmental Test of Visual-Motor Integration. Group results revealed no significant differences between the two tests, that they did correlate significantly, and that younger students had advanced visual-motor development when tested…

  1. A Comparison of the Koppitz and Hutt Techniques of Bender-Gestalt Administration Correlated with WISC-R Performance Scores.

    Science.gov (United States)

    Redfering, David L.; Collins, Jackie

    1982-01-01

    Forty elementary students were administered the Bender-Gestalt Test using two techniques: Koppitz routine instructions and the Hutt testing-the-limits method. The mean number of Koppitz errors was approximately two greater than the number obtained using the Hutt technique. (Author/BW)

  2. Expanded Koppitz Scoring System of the Bender Gestalt Visual-Motor Test for Adolescents: A Pilot Study.

    Science.gov (United States)

    Bolen, Larry M.; And Others

    1992-01-01

    Examined use of Bender Gestalt Visual-Motor Test with school-age adolescents over age 11. Mean error scores suggest that visual-motor development is not maturationally complete by age 11 years, 11 months. Suggests additional research focusing on extending normative sample or developing new scoring system for adolescents. (Author/NB)

  3. Developmental Model Using Gestalt-Play versus Cognitive-Verbal Group with Chinese Adolescents: Effects on Strengths and Adjustment Enhancement

    Science.gov (United States)

    Shen, Yih-Jiun

    2007-01-01

    This study compared the effectiveness of short-term developmental group counseling applying Gestalt-play versus cognitive-verbal approaches with Taiwanese adolescents. On a measure of behavioral and emotional strengths, teachers reported significant changes in students' overall behavioral and emotional strengths measured via total scores. Specific…

  4. A psicologia da gestalt e a ciência empírica contemporânea

    Directory of Open Access Journals (Sweden)

    Arno Engelmann

    Full Text Available Wertheimer realizou um experimento que era explicado seguindo-se fatores holísticos gestálticos, e isto há mais de noventa anos. Apesar disso, estudos recentes demonstram a vivacidade desse tipo de explicação. Basicamente, ao se observar coisas do mundo, observa-se suas formas ou melhor suas Gestalten. A seguir, pode-se dividir essas Gestalten em partes. Porém cada parte será sempre parte daquela Gestalt que lhe deu inicio e não um elemento constituinte básico. A teoria da Gestalt não é exclusivamente psicológica, como o demonstraram principalmente Wertheimer, Köhler e Koffka. Iniciou-se com um experimento sobre a visão de movimentos correspondendo a estímulos estáticos, mas continuou propondo-se inclusive, de um lado, uma Gestalt física formada da corrente elétrica gestálticas dentro de um condutor ou, de outro, uma Gestalt sociológica formada de muitos seres humanos, como o dançar de pares ao som de um samba realizado por um grupo de músicos.

  5. [Mechanism of heat transfer in various regions of human body].

    Science.gov (United States)

    Luchakov, Iu I; Nozdrachev, A D

    2009-01-01

    The processes of heat transfer in a human body were studied with the use of a mathematical model. It has been shown that only conductive or only convective heat transfer may occur in different body areas. The rate of blood-mediated heat transfer in the presence of blood circulation is many times higher than heat transfer due to temperature gradient; therefore, the convective process prevails over the conductive process. The body core contains a variety of blood vessels, and the bulk of blood concentrates there in the norm. Hence, heat transfer in it is mainly convective. In surface tissues, where the rate of blood circulation is lower and the vasculature has certain specific features, heat transfer is mainly conductive. Hence, the core and surface tissues are absolutely different body zones in terms of heat transfer.

  6. Human Energy Expenditure and Postural Coordination on the Mechanical Horse.

    Science.gov (United States)

    Baillet, Héloïse; Thouvarecq, Régis; Vérin, Eric; Tourny, Claire; Benguigui, Nicolas; Komar, John; Leroy, David

    2017-01-01

    The authors investigated and compared the energy expenditure and postural coordination of two groups of healthy subjects on a mechanical horse at 4 increasing oscillation frequencies. Energy expenditure was assessed from the oxygen consumption, respiratory quotient, and heart rate values, and postural coordination was characterized by relative phase computations between subjects (elbow, head, trunk) and horse. The results showed that the postural coordination of the riders was better adapted (i.e., maintenance of in-phase and antiphase) than that of the nonriders, but the energy expenditure remains the same. Likewise, we observed an energy system shifting only for nonriders (from aerobic to lactic anaerobic mode). Finally, cross-correlations showed a link between energy expenditure and postural coordination in the riders (i.e., effectiveness).

  7. Students' Learning Strategies with Multiple Representations: Explanations of the Human Breathing Mechanism

    Science.gov (United States)

    Won, Mihye; Yoon, Heojeong; Treagust, David F.

    2014-01-01

    The purpose of this study was to understand how students utilized multiple representations to learn and explain science concepts, in this case the human breathing mechanism. The study was conducted with Grade 11 students in a human biology class. Semistructured interviews and a two-tier diagnostic test were administered to evaluate students'…

  8. Modeling Human Error Mechanism for Soft Control in Advanced Control Rooms (ACRs)

    Energy Technology Data Exchange (ETDEWEB)

    Aljneibi, Hanan Salah Ali [Khalifa Univ., Abu Dhabi (United Arab Emirates); Ha, Jun Su; Kang, Seongkeun; Seong, Poong Hyun [KAIST, Daejeon (Korea, Republic of)

    2015-10-15

    To achieve the switch from conventional analog-based design to digital design in ACRs, a large number of manual operating controls and switches have to be replaced by a few common multi-function devices which is called soft control system. The soft controls in APR-1400 ACRs are classified into safety-grade and non-safety-grade soft controls; each was designed using different and independent input devices in ACRs. The operations using soft controls require operators to perform new tasks which were not necessary in conventional controls such as navigating computerized displays to monitor plant information and control devices. These kinds of computerized displays and soft controls may make operations more convenient but they might cause new types of human error. In this study the human error mechanism during the soft controls is studied and modeled to be used for analysis and enhancement of human performance (or human errors) during NPP operation. The developed model would contribute to a lot of applications to improve human performance (or reduce human errors), HMI designs, and operators' training program in ACRs. The developed model of human error mechanism for the soft control is based on assumptions that a human operator has certain amount of capacity in cognitive resources and if resources required by operating tasks are greater than resources invested by the operator, human error (or poor human performance) is likely to occur (especially in 'slip'); good HMI (Human-machine Interface) design decreases the required resources; operator's skillfulness decreases the required resources; and high vigilance increases the invested resources. In this study the human error mechanism during the soft controls is studied and modeled to be used for analysis and enhancement of human performance (or reduction of human errors) during NPP operation.

  9. Lymphoid Cell-Glioma Cell Interaction Enhances Cell Coat Production by Human Gliomas: Novel Suppressor Mechanism

    Science.gov (United States)

    Dick, Steven J.; Macchi, Beatrice; Papazoglou, Savvas; Oldfield, Edward H.; Kornblith, Paul L.; Smith, Barry H.; Gately, Maurice K.

    1983-05-01

    Certain human glioma lines produce mucopolysaccharide coats that impair the generation of cytolytic lymphocytes in response to these lines in vitro. Coat production is substantially enhanced by the interaction of glioma cells with a macromolecular factor released by human peripheral blood mononuclear cells in culture. This interaction thus constitutes an unusual mechanism by which inflammatory cells may nonspecifically suppress the cellular immune response to at least one class of solid tumors in humans.

  10. [Embryonic mechanisms in development of spina bifida in humans].

    Science.gov (United States)

    Vostrikov, O V; Zotov, V A; Nikitenko, E V

    2004-01-01

    The study of 86 human embryos and fetuses beginning from 23rdday of development up to 18th week after fecundation has detected 23 cases of pathologic development which correspond to the modern definition of spina bifida (SB). It is shown that the cause of various forms of the anomaly is the disturbance or temporary delay of a movement of caudal neurulation wave forming the spinal cord. The anomaly size and type are determined by the time and duration of a pathogenic action on neurulation. Postnatal or the 1st type of SB develops in neurulation wave disturbance not longer than 4-6 hours. Anomaly consequence may be compensated surgically. The 2nd or fetal type of SB arises when neurulation delay is from 6 to 20 hours. If the delay occurs on the 22-24th day of development, embryos die by the neurulation end. If the delay takes place on the 26-28th day embryos may survive till the late fetal period. In embryonal or type III of SB embryos die by the end of the 8th week and do not enter the medical statistics. Their death is associated with delayed movement of the caudal neurulation wave for 24 hours and longer. This results in a spontaneous abortion.

  11. Fisheries bycatch as an inadvertent human-induced evolutionary mechanism.

    Directory of Open Access Journals (Sweden)

    Christophe Barbraud

    Full Text Available Selective harvesting of animals by humans can affect the sustainability and genetics of their wild populations. Bycatch - the accidental catch of non-target species - spans the spectrum of marine fauna and constitutes a harvesting pressure. Individual differences in attraction to fishing vessels and consequent susceptibility to bycatch exist, but few studies integrate this individual heterogeneity with demography. Here, we tested for the evidence and consequences of individual heterogeneity on the demography of the wandering albatross, a seabird heavily affected by fisheries bycatch. We found strong evidence for heterogeneity in survival with one group of individuals having a 5.2% lower annual survival probability than another group, and a decrease in the proportion of those individuals with the lowest survival in the population coinciding with a 7.5 fold increase in fishing effort in the foraging areas. Potential causes for the heterogeneity in survival are discussed and we suggest that bycatch removed a large proportion of individuals attracted by fishing vessels and had significant phenotypic and population consequences.

  12. Epigenetic mechanisms in human adenovirus type 12 oncogenesis.

    Science.gov (United States)

    Doerfler, Walter

    2009-06-01

    For the past 30 years, my laboratory has concentrated its work on demonstrating that the epigenetic consequences of foreign DNA insertion into established mammalian genomes -de novo DNA methylation of the integrate and alterations of methylation patterns across the recipient genome - are essential elements in setting the stage towards oncogenic transformation. We have primarily studied human adenovirus type 12 (Ad12) which induces undifferentiated tumors in Syrian hamsters (Mesocricetus auratus) either at the site of subcutaneous Ad12 injection or intraperitoneally upon intramuscular injection. Up to 90% of the hamsters injected with Ad12 develop tumors within 3-6 weeks. Integration of foreign DNA, its de novo methylation, and the consequences of insertion on the cellular methylation and transcription profiles have been studied in detail. While viral infections are a frequent source of foreign genomes entering mammalian and other hosts and often their genomes, we have also pursued the fate of food-ingested foreign DNA in the mouse organism. The persistence of this DNA in the animals is transient and there is no evidence for the expression or germ line fixation of foreign DNA. Nevertheless, the occasional cell that carries integrated genomes from that foreign source deserves the oncologist's sustained interest.

  13. Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.

    Science.gov (United States)

    Pérez, J L

    1997-09-01

    Long term therapies needed for managing human cytomegalovirus (HCMV) infections in immunosupressed patients provided the background for the emergence of the resistance to antivirals active against HCMV. In addition, laboratory selected mutants have also been readily achieved. Both clinical and laboratory resistant strains share the same determinants of resistance. Ganciclovir resistance may be due to a few mutations in the HCMV UL97 gene and/or viral DNA pol gene, the former being responsible for about 70% of clinical resistant isolates. Among them, V464, V594, S595 and F595 are the most frequent mutations. Because of their less extensive clinical use, much less is known about resistance to foscarnet and cidofovir (formerly, HPMPC) but in both cases, it has been associated to mutations in the DNA pol. Ganciclovir resistant strains showing DNA pol mutations are cross-resistant to cidofovir and their corresponding IC50 are normally higher than those from strains harboring only mutations at the UL97 gene. To date, foscarnet resistance seems to be independent of both ganciclovir and cidofovir resistance.

  14. Overview of human obesity and central mechanisms regulating energy homeostasis.

    Science.gov (United States)

    Crowley, Vivion E F

    2008-05-01

    Obesity is now regarded as a global epidemic affecting both adults and children, and is associated with significant morbidity and mortality. Thus the effective management of obesity has become an important clinical focus. Therefore, an understanding of the pathways controlling appetite, satiety and food intake is critical for gaining an insight into the pathogenesis of obesity and also for the development of diagnostic tests and therapeutic agents for use in the clinical management of this condition. Over the last decade or more research using both mouse and human genetic models has elucidated the critical role of the leptin-melanocortin pathway in the hypothalamus, in regulating mammalian energy balance. In tandem with this, a clearer understanding of the regulation of gut-derived hormones and their interaction with the central nervous system has further illuminated the complex interplay between central and peripheral aspects of energy regulation. The obesity epidemic and the expanded knowledge base relating to its aetiopathogenesis have specific implications for clinical biochemistry. In particular, an increase in workload may be expected due to biochemical investigation of obesity and its co-morbidities. Moreover, advice on the in-depth investigation of complex cases of obesity may be sought, including information on newer diagnostic tests, such as serum leptin or molecular genetic analysis. There may also be a substantive role for chemical pathologists in establishing and running clinical obesity services. Finally, clinical biochemistry has a role in research pertaining to obesity and cardiometabolic risk.

  15. Planes of Phenomenological Experience: The Psychology of Deafness as an Early Example of American Gestalt Psychology, 1928-1940.

    Science.gov (United States)

    Schmidt, Marion A

    2017-07-17

    When, in 1928, the Clarke School for the Deaf in Northampton, Massachusetts, opened a psychological research division, it was nothing unusual in a time fascinated with the sciences of education. Yet with its longstanding ties to Northampton's Smith College, the school was able to secure the collaboration of eminent Gestalt psychologist Kurt Koffka, who, in turn, engaged 2 more German-speaking emigrants, Margarete Eberhardt and social psychologist Fritz Heider, and Heider's American wife Grace Moore Heider. This collaboration has seen little attention from historians, who have treated Koffka's and Heider's time in Northampton as a transitory phase. I argue, however, that their research on deafness adds to the history of emigration and knowledge transfer between European and American Schools of psychology, and to historical understanding of the interrelation of Gestalt, child, and social psychology. Professionals in child studies and developmental psychology were keenly interested in the holistic and introspective approach Gestalt psychology offered. Deaf children were considered a particularly fascinating research population for exploring the relationship between thought and language, perception and development, Gestalt, and reality. At the Clarke School, Grace Moore Heider was among the first Americans to apply Gestalt principles to child psychology. In a time in which pejorative eugenic beliefs dominated professional perceptions of disability, the Heiders' groundbreaking work defined the deaf as a social and phenomenological minority. This was in opposition to dominant beliefs in deaf education, yet it points to early roots of a social model of deafness and disability, which historians usually locate in 1960s and '70s activism. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Clinician gestalt estimate of pretest probability for acute coronary syndrome and pulmonary embolism in patients with chest pain and dyspnea.

    Science.gov (United States)

    Kline, Jeffrey A; Stubblefield, William B

    2014-03-01

    Pretest probability helps guide diagnostic testing for patients with suspected acute coronary syndrome and pulmonary embolism. Pretest probability derived from the clinician's unstructured gestalt estimate is easier and more readily available than methods that require computation. We compare the diagnostic accuracy of physician gestalt estimate for the pretest probability of acute coronary syndrome and pulmonary embolism with a validated, computerized method. This was a secondary analysis of a prospectively collected, multicenter study. Patients (N=840) had chest pain, dyspnea, nondiagnostic ECGs, and no obvious diagnosis. Clinician gestalt pretest probability for both acute coronary syndrome and pulmonary embolism was assessed by visual analog scale and from the method of attribute matching using a Web-based computer program. Patients were followed for outcomes at 90 days. Clinicians had significantly higher estimates than attribute matching for both acute coronary syndrome (17% versus 4%; Psyndrome (r(2)=0.15) and pulmonary embolism (r(2)=0.06). Areas under the receiver operating characteristic curve were lower for clinician estimate compared with the computerized method for acute coronary syndrome: 0.64 (95% confidence interval [CI] 0.51 to 0.77) for clinician gestalt versus 0.78 (95% CI 0.71 to 0.85) for attribute matching. For pulmonary embolism, these values were 0.81 (95% CI 0.79 to 0.92) for clinician gestalt and 0.84 (95% CI 0.76 to 0.93) for attribute matching. Compared with a validated machine-based method, clinicians consistently overestimated pretest probability but on receiver operating curve analysis were as accurate for pulmonary embolism but not acute coronary syndrome. Copyright © 2013 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

  17. Mechanism of action of ozone on the human lung

    Energy Technology Data Exchange (ETDEWEB)

    Hazucha, M.J.; Bates, D.V.; Bromberg, P.A. (Univ. of North Carolina, Chapel Hill (USA))

    1989-10-01

    Fourteen healthy normal volunteers were randomly exposed to air and 0.5 ppm of ozone (O3) in a controlled exposure chamber for a 2-h period during which 15 min of treadmill exercise sufficient to produce a ventilation of approximately 40 l/min was alternated with 15-min rest periods. Before testing an esophageal balloon was inserted, and lung volumes, flow rates, maximal inspiratory (at residual volume and functional residual capacity) and expiratory (at total lung capacity and functional residual capacity) mouth pressures, and pulmonary mechanics (static and dynamic compliance and airway resistance) were measured before and immediately after the exposure period. After the postexposure measurements had been completed, the subjects inhaled an aerosol of 20% lidocaine until response to citric acid aerosol inhalation was abolished. All of the measurements were immediately repeated. We found that the O3 exposure (1) induced a significant mean decrement of 17.8% in vital capacity (this change was the result of a marked fall in inspiratory capacity without significant increase in residual volume), (2) significantly increased mean airway resistance and specific airway resistance but did not change dynamic or static pulmonary compliance or viscous or elastic work, (3) significantly reduced maximal transpulmonary pressure (by 19%) but produced no changes in inspiratory or expiratory maximal mouth pressures, and (4) significantly increased respiratory rate (in 5 subjects by more than 6 breaths/min) and decreased tidal volume.

  18. Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η.

    Science.gov (United States)

    Su, Yan; Egli, Martin; Guengerich, F Peter

    2016-02-19

    Ribonucleotides and 2'-deoxyribonucleotides are the basic units for RNA and DNA, respectively, and the only difference is the extra 2'-OH group on the ribonucleotide sugar. Cellular rNTP concentrations are much higher than those of dNTP. When copying DNA, DNA polymerases not only select the base of the incoming dNTP to form a Watson-Crick pair with the template base but also distinguish the sugar moiety. Some DNA polymerases use a steric gate residue to prevent rNTP incorporation by creating a clash with the 2'-OH group. Y-family human DNA polymerase η (hpol η) is of interest because of its spacious active site (especially in the major groove) and tolerance of DNA lesions. Here, we show that hpol η maintains base selectivity when incorporating rNTPs opposite undamaged DNA and the DNA lesions 7,8-dihydro-8-oxo-2'-deoxyguanosine and cyclobutane pyrimidine dimer but with rates that are 10(3)-fold lower than for inserting the corresponding dNTPs. X-ray crystal structures show that the hpol η scaffolds the incoming rNTP to pair with the template base (dG) or 7,8-dihydro-8-oxo-2'-deoxyguanosine with a significant propeller twist. As a result, the 2'-OH group avoids a clash with the steric gate, Phe-18, but the distance between primer end and Pα of the incoming rNTP increases by 1 Å, elevating the energy barrier and slowing polymerization compared with dNTP. In addition, Tyr-92 was identified as a second line of defense to maintain the position of Phe-18. This is the first crystal structure of a DNA polymerase with an incoming rNTP opposite a DNA lesion.

  19. Facilitation by exogenous attention for static and dynamic gestalt groups.

    Science.gov (United States)

    Gonen, Fahrettin F; Hallal, Hamza; Ogmen, Haluk

    2014-08-01

    Attentional mechanisms allow the brain to selectively allocate its resources to stimuli of interest within the huge amount of information reaching its sensory systems. The voluntary component of attention, endogenous attention, can be allocated in a flexible manner depending on the goals and strategies of the observer. On the other hand, the reflexive component, exogenous attention, is driven by the stimulus. Here, we investigated how exogenous attention is deployed to moving stimuli that form distinct perceptual groups. We showed that exogenous attention is deployed according to a reference frame that moves along with the stimulus. Moreover, in addition to the cued stimulus, exogenous attention is deployed to all elements forming a perceptual group. These properties provide a basis for the efficient deployment of exogenous attention under ecological viewing conditions.

  20. Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans.

    Science.gov (United States)

    Indovina, Iole; Robbins, Trevor W; Núñez-Elizalde, Anwar O; Dunn, Barnaby D; Bishop, Sonia J

    2011-02-10

    Investigations of fear conditioning in rodents and humans have illuminated the neural mechanisms underlying cued and contextual fear. A critical question is how personality dimensions such as trait anxiety act through these mechanisms to confer vulnerability to anxiety disorders, and whether humans' ability to overcome acquired fears depends on regulatory skills not characterized in animal models. In a neuroimaging study of fear conditioning in humans, we found evidence for two independent dimensions of neurocognitive function associated with trait vulnerability to anxiety. The first entailed increased amygdala responsivity to phasic fear cues. The second involved impoverished ventral prefrontal cortical (vPFC) recruitment to downregulate both cued and contextual fear prior to omission (extinction) of the aversive unconditioned stimulus. These two dimensions may contribute to symptomatology differences across anxiety disorders; the amygdala mechanism affecting the development of phobic fear and the frontal mechanism influencing the maintenance of both specific fears and generalized anxiety.

  1. Insights into the Phosphoryl Transfer Mechanism of Human Ubiquitous Mitochondrial Creatine Kinase.

    Science.gov (United States)

    Li, Quanjie; Fan, Shuai; Li, Xiaoyu; Jin, Yuanyuan; He, Weiqing; Zhou, Jinming; Cen, Shan; Yang, ZhaoYong

    2016-12-02

    Human ubiquitous mitochondrial creatine kinase (uMtCK) is responsible for the regulation of cellular energy metabolism. To investigate the phosphoryl-transfer mechanism catalyzed by human uMtCK, in this work, molecular dynamic simulations of uMtCK∙ATP-Mg(2+)∙creatine complex and quantum mechanism calculations were performed to make clear the puzzle. The theoretical studies hereof revealed that human uMtCK utilizes a two-step dissociative mechanism, in which the E227 residue of uMtCK acts as the catalytic base to accept the creatine guanidinium proton. This catalytic role of E227 was further confirmed by our assay on the phosphatase activity. Moreover, the roles of active site residues in phosphoryl transfer reaction were also identified by site directed mutagenesis. This study reveals the structural basis of biochemical activity of uMtCK and gets insights into its phosphoryl transfer mechanism.

  2. A Pilot Study of Visual-Motor Developmental Inter-Test Reliability: The Beery Developmental Test of Visual Motor Integration and the Bender Visual Motor Gestalt Test.

    Science.gov (United States)

    Porter, Gary L.; Binder, Dorothy M.

    1981-01-01

    To determine the intertest reliability of the Beery Developmental Test of Visual Motor Integration (VMI) and the Bender Visual Motor Gestalt Test (BGT), 64 six to nine year olds were administered both tests.

  3. Mechanical characterization of human brain tumors from patients and comparison to potential surgical phantoms.

    Science.gov (United States)

    Stewart, Daniel C; Rubiano, Andrés; Dyson, Kyle; Simmons, Chelsey S

    2017-01-01

    While mechanical properties of the brain have been investigated thoroughly, the mechanical properties of human brain tumors rarely have been directly quantified due to the complexities of acquiring human tissue. Quantifying the mechanical properties of brain tumors is a necessary prerequisite, though, to identify appropriate materials for surgical tool testing and to define target parameters for cell biology and tissue engineering applications. Since characterization methods vary widely for soft biological and synthetic materials, here, we have developed a characterization method compatible with abnormally shaped human brain tumors, mouse tumors, animal tissue and common hydrogels, which enables direct comparison among samples. Samples were tested using a custom-built millimeter-scale indenter, and resulting force-displacement data is analyzed to quantify the steady-state modulus of each sample. We have directly quantified the quasi-static mechanical properties of human brain tumors with effective moduli ranging from 0.17-16.06 kPa for various pathologies. Of the readily available and inexpensive animal tissues tested, chicken liver (steady-state modulus 0.44 ± 0.13 kPa) has similar mechanical properties to normal human brain tissue while chicken crassus gizzard muscle (steady-state modulus 3.00 ± 0.65 kPa) has similar mechanical properties to human brain tumors. Other materials frequently used to mimic brain tissue in mechanical tests, like ballistic gel and chicken breast, were found to be significantly stiffer than both normal and diseased brain tissue. We have directly compared quasi-static properties of brain tissue, brain tumors, and common mechanical surrogates, though additional tests would be required to determine more complex constitutive models.

  4. Diagnostically relevant facial gestalt information from ordinary photos.

    Science.gov (United States)

    Ferry, Quentin; Steinberg, Julia; Webber, Caleb; FitzPatrick, David R; Ponting, Chris P; Zisserman, Andrew; Nellåker, Christoffer

    2014-06-24

    Craniofacial characteristics are highly informative for clinical geneticists when diagnosing genetic diseases. As a first step towards the high-throughput diagnosis of ultra-rare developmental diseases we introduce an automatic approach that implements recent developments in computer vision. This algorithm extracts phenotypic information from ordinary non-clinical photographs and, using machine learning, models human facial dysmorphisms in a multidimensional 'Clinical Face Phenotype Space'. The space locates patients in the context of known syndromes and thereby facilitates the generation of diagnostic hypotheses. Consequently, the approach will aid clinicians by greatly narrowing (by 27.6-fold) the search space of potential diagnoses for patients with suspected developmental disorders. Furthermore, this Clinical Face Phenotype Space allows the clustering of patients by phenotype even when no known syndrome diagnosis exists, thereby aiding disease identification. We demonstrate that this approach provides a novel method for inferring causative genetic variants from clinical sequencing data through functional genetic pathway comparisons.DOI: http://dx.doi.org/10.7554/eLife.02020.001.

  5. Comparison of the unstructured clinician gestalt, the wells score, and the revised Geneva score to estimate pretest probability for suspected pulmonary embolism.

    Science.gov (United States)

    Penaloza, Andrea; Verschuren, Franck; Meyer, Guy; Quentin-Georget, Sybille; Soulie, Caroline; Thys, Frédéric; Roy, Pierre-Marie

    2013-08-01

    The assessment of clinical probability (as low, moderate, or high) with clinical decision rules has become a cornerstone of diagnostic strategy for patients with suspected pulmonary embolism, but little is known about the use of physician gestalt assessment of clinical probability. We evaluate the performance of gestalt assessment for diagnosing pulmonary embolism. We conducted a retrospective analysis of a prospective observational cohort of consecutive suspected pulmonary embolism patients in emergency departments. Accuracy of gestalt assessment was compared with the Wells score and the revised Geneva score by the area under the curve (AUC) of receiver operating characteristic curves. Agreement between the 3 methods was determined by κ test. The study population was 1,038 patients, with a pulmonary embolism prevalence of 31.3%. AUC differed significantly between the 3 methods and was 0.81 (95% confidence interval [CI] 0.78 to 0.84) for gestalt assessment, 0.71 (95% CI 0.68 to 0.75) for Wells, and 0.66 (95% CI 0.63 to 0.70) for the revised Geneva score. The proportion of patients categorized as having low clinical probability was statistically higher with gestalt than with revised Geneva score (43% versus 26%; 95% CI for the difference of 17%=13% to 21%). Proportion of patients categorized as having high clinical probability was higher with gestalt than with Wells (24% versus 7%; 95% CI for the difference of 17%=14% to 20%) or revised Geneva score (24% versus 10%; 95% CI for the difference of 15%=13% to 21%). Pulmonary embolism prevalence was significantly lower with gestalt versus clinical decision rules in low clinical probability (7.6% for gestalt versus 13.0% for revised Geneva score and 12.6% for Wells score) and non-high clinical probability groups (18.3% for gestalt versus 29.3% for Wells and 27.4% for revised Geneva score) and was significantly higher with gestalt versus Wells score in high clinical probability groups (72.1% versus 58.1%). Agreement

  6. La Definición del Concepto de Percepción en Psicología con Base en la Teoria Gestalt

    OpenAIRE

    Gilberto Leonardo Oviedo

    2004-01-01

    This article presents the contribution of the Gestalt theory (Theory of the form) in the definition of the perceptual concept. It begins with the philosophical analysis of the formulated by the asociacionist and then follow with the subsequently debate established between this philosophical view and the representatives of the Gestalt movement.The main laws of perception, with special emphasis in the principle of the good contours and the holism are particularly examinated. Finally, the conclu...

  7. Mechanical loading and the synthesis of 1,25(OH)2D in primary human osteoblasts.

    Science.gov (United States)

    van der Meijden, K; Bakker, A D; van Essen, H W; Heijboer, A C; Schulten, E A J M; Lips, P; Bravenboer, N

    2016-02-01

    The metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D) is synthesized from its precursor 25-hydroxyvitamin D (25(OH)D) by human osteoblasts leading to stimulation of osteoblast differentiation in an autocrine or paracrine way. Osteoblast differentiation is also stimulated by mechanical loading through activation of various responses in bone cells such as nitric oxide signaling. Whether mechanical loading affects osteoblast differentiation through an enhanced synthesis of 1,25(OH)2D by human osteoblasts is still unknown. We hypothesized that mechanical loading stimulates the synthesis of 1,25(OH)2D from 25(OH)D in primary human osteoblasts. Since the responsiveness of bone to mechanical stimuli can be altered by various endocrine factors, we also investigated whether 1,25(OH)2D or 25(OH)D affect the response of primary human osteoblasts to mechanical loading. Primary human osteoblasts were pre-incubated in medium with/without 25(OH)D3 (400 nM) or 1,25(OH)2D3 (100 nM) for 24h and subjected to mechanical loading by pulsatile fluid flow (PFF). The response of osteoblasts to PFF was quantified by measuring nitric oxide, and by PCR analysis. The effect of PFF on the synthesis of 1,25(OH)2D3 was determined by subjecting osteoblasts to PFF followed by 24h post-incubation in medium with/without 25(OH)D3 (400 nM). We showed that 1,25(OH)2D3 reduced the PFF-induced NO response in primary human osteoblasts. 25(OH)D3 did not significantly alter the NO response of primary human osteoblasts to PFF, but 25(OH)D3 increased osteocalcin and RANKL mRNA levels, similar to 1,25(OH)2D3. PFF did not increase 1,25(OH)2D3 amounts in our model, even though PFF did increase CYP27B1 mRNA levels and reduced VDR mRNA levels. CYP24 mRNA levels were not affected by PFF, but were strongly increased by both 25(OH)D3 and 1,25(OH)2D3. In conclusion, 1,25(OH)2D3 may affect the response of primary human osteoblasts to mechanical stimuli, at least with respect to NO production. Mechanical stimuli may affect

  8. On the other hand: Increased cortical activation to human versus mechanical hands in infants.

    Science.gov (United States)

    Biondi, Marisa; Boas, David A; Wilcox, Teresa

    2016-11-01

    There is a large body of work demonstrating that infants are sensitive to the distinction between human and mechanical entities from the early months of life, and have different expectations for the way these entities move and interact. The current work investigates the extent to which the functional organization of the immature brain reflects these early emerging sensitivities. Infants aged 8months watched two kinds of hands (human or mechanical) engage in two kinds of events (one with a functional outcome and one without). Using functional near-infrared spectroscopy (fNIRS), we assessed hemodynamic activation in the left and right temporal and temporal-occipital cortex in response to these events. The neuroimaging data revealed a significantly greater increase in activation in the right middle-posterior temporal cortex to events executed by the human than the mechanical hand; the event in which the hand engaged (function or non-function) did not significantly influence hemodynamic responses. In comparison, the left middle-temporal cortex showed significantly greater activation to events executed by the human than mechanical hand, but only when the events were functionally relevant. That is, the left middle-posterior temporal cortex responded selectively to human (as compared to mechanical) agents, but only in the context of functionally relevant actions on objects. These results reveal that the immature brain is functionally specialized to support infants' processing of human and non-human agents as distinct entities. These results also shed light on the cognitive and cortical mechanisms that guide infants' learning about agentive action and object function.

  9. Energy cost and mechanical efficiency of riding a human-powered recumbent bicycle.

    Science.gov (United States)

    Capelli, Carlo; Ardigo, Luca Paolo; Schena, Federico; Zamparo, Paola

    2008-10-01

    When dealing with human-powered vehicles, it is important to quantify the capability of converting metabolic energy in useful mechanical work by measuring mechanical efficiency. In this study, net mechanical efficiency (eta) of riding a recumbent bicycle on flat terrain and at constant speeds (v, 5.1-10.0 m/s) was calculated dividing mechanical work (w, J/m) by the corresponding energy cost (C(c), J/m). w and C(c) increased linearly with the speed squared: w = 9.41 + 0.156 . v(2); C(c) = 39.40 + 0.563 . v(2). eta was equal to 0.257 +/- 0.0245, i.e. identical to that of concentric muscular contraction. Hence, i) eta seems unaffected by the biomechanical arrangement of the human-vehicle system; ii) the efficiency of transmission seems to be close to 100%, suggesting that the particular biomechanical arrangement does not impair the transformation of metabolic energy in mechanical work. When dealing with human-powered vehicles, it is important to quantify mechanical efficiency (eta) of locomotion. eta of riding a recumbent bicycle was calculated dividing the mechanical work to the corresponding energy cost of locomotion; it was practically identical to that of concentric muscular contraction (0.257 +/- 0.0245), suggesting that the power transmission from muscles to pedals is unaffected by the biomechanical arrangement of the vehicle.

  10. Ruling Out Pulmonary Embolism in Primary Care: Comparison of the Diagnostic Performance of "Gestalt" and the Wells Rule.

    Science.gov (United States)

    Hendriksen, Janneke M T; Lucassen, Wim A M; Erkens, Petra M G; Stoffers, Henri E J H; van Weert, Henk C P M; Büller, Harry R; Hoes, Arno W; Moons, Karel G M; Geersing, Geert-Jan

    2016-05-01

    Diagnostic prediction models such as the Wells rule can be used for safely ruling out pulmonary embolism (PE) when it is suspected. A physician's own probability estimate ("gestalt"), however, is commonly used instead. We evaluated the diagnostic performance of both approaches in primary care. Family physicians estimated the probability of PE on a scale of 0% to 100% (gestalt) and calculated the Wells rule score in 598 patients with suspected PE who were thereafter referred to secondary care for definitive testing. We compared the discriminative ability (c statistic) of both approaches. Next, we stratified patients into PE risk categories. For gestalt, a probability of less than 20% plus a negative point-of-care d-dimer test indicated low risk; for the Wells rule, we used a score of 4 or lower plus a negative d-dimer test. We compared sensitivity, specificity, efficiency (percentage of low-risk patients in total cohort), and failure rate (percentage of patients having PE within the low-risk category). With 3 months of follow-up, 73 patients (12%) were confirmed to have venous thromboembolism (a surrogate for PE at baseline). The c statistic was 0.77 (95% CI, 0.70-0.83) for gestalt and 0.80 (95% CI, 0.75-0.86) for the Wells rule. Gestalt missed 2 out of 152 low-risk patients (failure rate = 1.3%; 95% CI, 0.2%-4.7%) with an efficiency of 25% (95% CI, 22%-29%); the Wells rule missed 4 out of 272 low-risk patients (failure rate = 1.5%; 95% CI, 0.4%-3.7%) with an efficiency of 45% (95% CI, 41%-50%). Combined with d-dimer testing, both gestalt using a cutoff of less than 20% and the Wells rule using a score of 4 or lower are safe for ruling out PE in primary care. The Wells rule is more efficient, however, and PE can be ruled out in a larger proportion of suspected cases. © 2016 Annals of Family Medicine, Inc.

  11. Discovery of multi-ring basins - Gestalt perception in planetary science

    Science.gov (United States)

    Hartmann, W. K.

    1981-01-01

    Early selenographers resolved individual structural components of multi-ring basin systems but missed the underlying large-scale multi-ring basin patterns. The recognition of multi-ring basins as a general class of planetary features can be divided into five steps. Gilbert (1893) took a first step in recognizing radial 'sculpture' around the Imbrium basin system. Several writers through the 1940's rediscovered the radial sculpture and extended this concept by describing concentric rings around several circular maria. Some reminiscences are given about the fourth step - discovery of the Orientale basin and other basin systems by rectified lunar photography at the University of Arizona in 1961-62. Multi-ring basins remained a lunar phenomenon until the fifth step - discovery of similar systems of features on other planets, such as Mars (1972), Mercury (1974), and possibly Callisto and Ganymede (1979). This sequence is an example of gestalt recognition whose implications for scientific research are discussed.

  12. Hiperatividade: doença ou essência um enfoque da gestalt-terapia

    OpenAIRE

    Sheila Antony; Jorge Ponciano Ribeiro

    2005-01-01

    Este trabalho discute a hiperatividade considerando a metáfora do corpo da criança e o seu funcionamento psicológico, de forma a esclarecer se a sua expressão constitui doença ou um modo próprio de ser. O transtorno de déficit de atenção/hiperatividade (TDAH) tem sido extensivamente investigado em pesquisas que visam aprimorar os critérios diagnósticos e conhecer sua etiologia. Poucos estudos são orientados para elucidar a dimensão psíquica da criança hiperativa. A Gestalt-Terapia é uma abord...

  13. Comparison of the Bender-Gestalt and revised Developmental Test of Visual-Motor Integration.

    Science.gov (United States)

    Armstrong, B B; Knopf, K F

    1982-08-01

    The Bender-Gestalt and the Developmental Test of Visual-motor Integration were administered to two groups of 40 children each, ages 7 through 10 yr. Developmental age scores (Koppitz scoring) and age equivalents (Revised Beery manual) were obtained. Children screened for learning disabilities were selected for one group and children enrolled in regular classrooms were selected for another group. The correlation of .74 between the Bender and Beery test scores was high and statistically significant for the learning-disabled group. The correlation of .36 was low though statistically significant for the regular students, which suggests the groups performed differently on the tests. A significant mean difference of 9 mo. was noted between the Bender and Beery scores.

  14. Turkish children's Bender-Gestalt Test performance: a pilot study and preliminary norms.

    Science.gov (United States)

    Ozer, Serap

    2007-12-01

    The present study was undertaken to provide preliminary data for norms on the Bender-Gestalt Test for 253 children ages 5 yr., 5 mo. to 11 yr., 10 mo. in Turkey. The Koppitz Developmental Scoring System gave mean error scores of 4.2 (SD = 3.3) for girls and 3.6 (SD = 3.0) for boys. The mean error scores obtained by all age groups are presented and compared with other cross-cultural data. These scores decreased across age groups, supporting Bender's maturational hypothesis of the test. The present sample performed at a higher developmental level than the Koppitz normative sample for the 5- and 6-year age groups, while means for other age groups were similar to the original U.S. norms. That this pattern is supported in other cross-cultural studies is discussed as well as the importance of developing local norms for visual spatial tests.

  15. The Bender-Gestalt psychopathology scale: failure to infer validity in a school-aged sample.

    Science.gov (United States)

    Rossini, E D

    1993-06-01

    The concurrent validity of Hutt's (1977) empirical psychopathology scale of the Bender Visual-Motor Gestalt Test was evaluated among three groups of younger school-aged children within the 7-to-10- year age range (M = 109.1): adjustment disordered, conduct disordered, and nonclinical controls (n = 40/group). Excellent interscorer reliability was achieved with approximately 2 hr of self-study of the scoring manual. Although the conduct-disordered group was significantly more immature on Koppitz' Developmental Scoring System, there were no significant differences among groups on the psychopathology scale when visual-motor development was covaried (M = 50.5). This was an unexpected result, given Hutt's initial validation study among school-aged children. The psychopathology scale was not inferred to be valid among adolescents in the only known concurrent validation study. Pending supportive validation research, the psychopathology scale should not be employed in the clinical assessment of younger school-aged children.

  16. Effects of serial position on Bender-Gestalt errors using Koppitz's criteria.

    Science.gov (United States)

    Nyfield, B; Patalano, F

    1998-12-01

    The validity of the Koppitz Developmental scoring system in identifying organic impairment among functionally impaired adolescents was challenged in the current study. It was proposed that there are two distinct subtypes of errors in this system: those that are valid indicators of organic impairment (Category A) and those which are not but occur as a function of specific emotional factors (Category B). 46 male adolescents with a primary diagnosis of Conduct Disorder, Oppositional Defiant Disorder, or Attention-Deficit Hyperactivity Disorder were administered the Bender-Gestalt once using the standard order of administration and once in reverse order. It was hypothesized that more errors would be committed on cards presented later than those presented earlier in sequence for Category B but not Category A errors. Analysis provided partial support for this hypothesis.

  17. The Bender-Gestalt as a method of personality assessment with adolescents.

    Science.gov (United States)

    Belter, R W; McIntosh, J A; Finch, A J; Williams, L D; Edwards, G L

    1989-05-01

    Normative data are presented for two Bender-Gestalt scoring systems with a sample of "normal" controls (n = 150), emotionally disturbed (n = 140), and mentally retarded/neurologically impaired (MR/NI) adolescents (n = 47), aged 12 to 17 years. The results failed to support the use of Hutt's (1985) Psychopathology Scale and Adolescent Configuration in differentiating the "normal" and emotionally disturbed groups, but did support their use in differentiating the MR/NI group from the other two. The Hutt scores also were found to be related inversely to age and IQ. By contrast, the Koppitz scores differentiated the three groups from each other and were not related significantly to IQ. The results supported limited use of Koppitz's (1975) Emotional Indicators as a "sign" approach to brief screening for emotional disturbance in adolescents.

  18. Gestalt-terapia herança em re-vista

    OpenAIRE

    Patrícia Wallerstein Gomes

    2001-01-01

    Este trabalho investiga e discute as possíveis razões que levaram a Gestalt-terapia a ter a imagem de uma abordagem frágil, sem consistência teórica e, portanto, mais fácil de ser exercida, vez que não exigiria do profissional uma capacitação teórica ou a necessidade de estudos mais aprofundados. A autora, definindo-se como herdeira desta abordagem, resgata sua origem e concepção, apontando a importância dos pais, Fritz e Laura Perls, considerando suas crenças, mitos e valores pessoais e a in...

  19. Hiperatividade: doença ou essência um enfoque da gestalt-terapia

    Directory of Open Access Journals (Sweden)

    Sheila Antony

    Full Text Available Este trabalho discute a hiperatividade considerando a metáfora do corpo da criança e o seu funcionamento psicológico, de forma a esclarecer se a sua expressão constitui doença ou um modo próprio de ser. O transtorno de déficit de atenção/hiperatividade (TDAH tem sido extensivamente investigado em pesquisas que visam aprimorar os critérios diagnósticos e conhecer sua etiologia. Poucos estudos são orientados para elucidar a dimensão psíquica da criança hiperativa. A Gestalt-Terapia é uma abordagem fenomenológico-existencial assentada em teorias holísticas que reconhecem a multidimensionalidade do humano, enfocando a relação (o contato como ontológica à existência humana.

  20. Gestalt-Terapia e Terapia Sistêmica: o corpo em psicoterapia

    Directory of Open Access Journals (Sweden)

    Marília Toscano de Araujo Gurgel

    2008-06-01

    Full Text Available Este trabalho demonstra a contribuição da abordagem corporal da Gestalt-Terapia para a Terapia Familiar Sistêmica. O método utilizado foi a gravação de uma oficina de corpo estruturada em saberes das duas abordagens. A oficina proporcionou, a cada participante, maior qualidade de atenção, presença, contato e criatividade, uma forma mais integrada de construir sua identidade. O entrecruzamento das duas abordagens trouxe às pessoas maior consciência de quem são e como são no "mundo", ajudando-as no processo de assunção da história que contam. A experiência mostrou aos terapeutas as possibilidades que o trabalho corporal oferece como método de apreensão da realidade co-construída.