WorldWideScience

Sample records for human ethical sense

  1. [Scientific ethics of human cloning].

    Science.gov (United States)

    Valenzuela, Carlos Y

    2005-01-01

    True cloning is fission, budding or other types of asexual reproduction. In humans it occurs in monozygote twinning. This type of cloning is ethically and religiously good. Human cloning can be performed by twinning (TWClo) or nuclear transfer (NTClo). Both methods need a zygote or a nuclear transferred cell, obtained in vitro (IVTec). They are under the IVTec ethics. IVTecs use humans (zygotes, embryos) as drugs or things; increase the risk of malformations; increase development and size of abnormalities and may cause long-term changes. Cloning for preserving extinct (or almost extinct) animals or humans when sexual reproduction is not possible is ethically valid. The previous selection of a phenotype in human cloning violates some ethical principles. NTClo for reproductive or therapeutic purposes is dangerous since it increases the risk for nucleotide or chromosome mutations, de-programming or re-programming errors, aging or malignancy of the embryo cells thus obtained.

  2. The Ethics of Human Spaceflight

    Science.gov (United States)

    Zoloth, Laurie

    2005-01-01

    This chapter intends to lay out some essential ethics questions that might frame the next step of space exploration. In this, I undertake two sorts of tasks. The first is to respond to the core ethic question: Is it ethical to travel in space? The second, assuming for the moment that I can convince you that the first premise can be justified, is to comment on what ethical challenges will face us there. It is appropriate to have a philosopher comment on this at the fortieth anniversary celebration, since it was also in 1962 that the National Academy of Science first convened a panel of philosophers to comment on space travel. They asked at that time whether it was indeed a worthwhile pursuit to travel in space and what might be expected of such an effort. What is at stake in any such boundary crossing is how the changing of essential human perimeters changes our own moral status. Will such boundary crossing worsen our human condition, or will it enhance it? In this way, the geopolitical quest is then linked to the quest for ontology, Pisarro hunting for the fountain of youth, for gold, and for territory. What follows are a series of ethical claims that link the problem of discovery in the larger world and the attendant ethical dilemmas of our explorations, as well as how this exploration alters our concepts of life on Earth. In this, the role of the ethicist is to function as both a skeptic and a stranger, aware of the optimism of science and the pessimism of philosophy.

  3. Overview on business ethics and human resources management ethics

    Directory of Open Access Journals (Sweden)

    Prof. Ph.D. Cãtãlina Bonciu

    2008-05-01

    Full Text Available In the contemporary business world ethics represents one of the most exciting challenges,precisely because there is still no universally valid modality for solving a problem of this kind. Adopting anethic personal behavior does not always ensure winning in the problems regarding the actual business, norin the organizational behavior itself. The personal values, either native or gained by an individual throughouthis socializing do not represent a support or advantage in the attitude towards the economic life. What is it that actually concerns the managers:to succeed in their activity or to have an ethic activity? A successful business is necessarily an ethic one, or one lacking ethics? In particular, should the human resources manager choose the human factor of solid moral and ethic grounds, or the one exclusively focused on money quantifiable performance?

  4. Ethical Considerations in Human Movement Research.

    Science.gov (United States)

    Olivier, Steve

    1995-01-01

    Highlights ethical issues for human subject research, identifying principles that form the construct of a code of research ethics and evaluating against this construct past human experimentation and current research in human movement studies. The efficacy of legislation and self-regulation is examined. Particular attention is given to the context…

  5. Public health nursing, ethics and human rights.

    Science.gov (United States)

    Ivanov, Luba L; Oden, Tami L

    2013-05-01

    Public health nursing has a code of ethics that guides practice. This includes the American Nurses Association Code of Ethics for Nurses, Principles of the Ethical Practice of Public Health, and the Scope and Standards of Public Health Nursing. Human rights and Rights-based care in public health nursing practice are relatively new. They reflect human rights principles as outlined in the Universal Declaration of Human Rights and applied to public health practice. As our health care system is restructured and there are new advances in technology and genetics, a focus on providing care that is ethical and respects human rights is needed. Public health nurses can be in the forefront of providing care that reflects an ethical base and a rights-based approach to practice with populations.

  6. Human research ethics committees in technical universities.

    Science.gov (United States)

    Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

    2014-07-01

    Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee.

  7. Making sense of ethics and law in the medical curriculum.

    Science.gov (United States)

    Dowie, A L

    2011-01-01

    The moment a patient comes into the treatment room, the medical professional is placed in both an ethical and a legal context. The task for medical teachers is to equip students for this clinical reality in a way that makes sense both to the learners and to the variety of medical educators in the school, all of whom will have their own interpretations of the nature of this subject area. Ethics and law in the medical curriculum (Dowie and Martin 2011), aims to provide an understanding of how ethics and law can be incorporated into the curriculum in a structured, coherent, and logical manner. It is essential that we begin with a vision of the primary purpose of our course, and clarify the overall domain of learning to which it relates. Rather than presenting students with a miscellany of ethico-legal topics, their learning can be reinforced by constructing a frame around the key emphases in law and ethics. A professional ethics frame is proposed, highlighting the everyday, theory-based, habits, intentions, consequences and society elements of this approach. The course also has to be mediated within the wider curriculum, and this benefits from a coherent and communicated course scheme that is directly meaningful within the educational setting of the medical school. Finally, within the Guide, examples of humanistic schemes are presented that centre on aspects of boundary in patient care, themed around body, person and community of practice.

  8. A Survey of Ethics Content in College-Level Remote Sensing Courses in the United States

    Science.gov (United States)

    Wetherholt, William A.; Rundquist, Bradley C.

    2010-01-01

    Easier access to submeter imagery has fueled debates over ethical uses of remote sensing. Some have called for ethics instruction to counter undesired uses of the technology. Here, this article reports the results of a survey examining attitudes related to teaching ethics in remote sensing. It was found that 52 percent of respondents teaching…

  9. Climate change, ethics and human security

    National Research Council Canada - National Science Library

    O'Brien, Karen L; St. Clair, Asuncion Lera; Kristoffersen, Berit; Cohen, Stewart J

    2010-01-01

    "Presenting human security perspectives on climate change, this volume raises issues of equity, ethics and environmental justice, as well as our capacity to respond to what is increasingly considered...

  10. Future global ethics: environmental change, embedded ethics, evolving human identity.

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2014-01-01

    markdownabstract__Abstract__ Work on global ethics looks at ethical connections on a global scale. It should link closely to environmental ethics, recognizing that we live in unified social-ecological systems, and to development ethics, attending systematically to the lives and interests of contemp

  11. Human Genome Editing and Ethical Considerations.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Singh, Bahadur

    2016-04-01

    Editing human germline genes may act as boon in some genetic and other disorders. Recent editing of the genome of the human embryo with the CRISPR/Cas9 editing tool generated a debate amongst top scientists of the world for the ethical considerations regarding its effect on the future generations. It needs to be seen as to what transformation human gene editing brings to humankind in the times to come.

  12. "Goodbye Dolly?" The ethics of human cloning.

    Science.gov (United States)

    Harris, J

    1997-01-01

    The ethical implications of human clones have been much alluded to, but have seldom been examined with any rigour. This paper examines the possible uses and abuses of human cloning and draws out the principal ethical dimensions, both of what might be done and its meaning. The paper examines some of the major public and official responses to cloning by authorities such as President Clinton, the World Health Organisation, the European parliament, UNESCO, and others and reveals their inadequacies as foundations for a coherent public policy on human cloning. The paper ends by defending a conception of reproductive rights of "procreative autonomy" which shows human cloning to be not inconsistent with human rights and dignity. PMID:9451604

  13. A Theoretical Framework for Human and Veterinary Medical Ethics Education

    Science.gov (United States)

    Magalhães-Sant'Ana, Manuel

    2016-01-01

    In their practice, physicians and veterinarians need to resort to an array of ethical competences. As a teaching topic, however, there is no accepted gold standard for human medical ethics, and veterinary medical ethics is not yet well established. This paper provides a reflection on the underlying aims of human and veterinary medical ethics…

  14. The ethics of human reproductive cloning.

    Science.gov (United States)

    Strong, Carson

    2005-03-01

    This article addresses the question of whether human reproductive cloning could be ethically justifiable in at least some cases involving infertile couples who would choose cloning as a way to have a genetically related child. At present, the risk of congenital anomalies constitutes a compelling argument against human reproductive cloning. The article explores whether reproductive cloning could be ethically justifiable if, at some future time, cloning becomes possible without an elevated risk of anomalies. It is argued that freedom to use cloning is a form of procreative freedom and, as such, deserves respect. All of the objections that have been raised against human reproductive cloning fall under three main categories: those that appeal to the interests of the child, those based on consequences for society, and those arising from teleological views. Objections that appeal to the child's interests are, in turn, of two main kinds: consequentialist and deontological. All of these types of objections are examined, and it is found that each involves serious problems that prevent it from being a reasonable objection in the context of the infertility cases considered. It is concluded that human reproductive cloning would be ethically justifiable in at least some cases involving infertile couples, provided that it could be performed without an elevated risk of anomalies.

  15. Human reproduction: possibilities and ethical borders.

    Directory of Open Access Journals (Sweden)

    Pr RenĂŠ Frydman

    2010-01-01

    Full Text Available Reproductive medicine is a new important field in all the countries. The possibilities are tremendous, therefore we have to decide if limits are necessary or should we consider that everything that have been initiated (as clone, gene transfer... can be apply in humans. That will be the challenge of a global ethical approach in each country with their culture, morality, guidelines or laws.

  16. Global Ethics and Human Security

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2009-01-01

    textabstractTerms like ‘human security’ try to catch the attention of an audience and to catch the user’s own attention; in other words they aim to stimulate and motivate. Having caught attention they try to organize it: they link to a perspective, a direction for and way of looking. Having caught a

  17. Principles for ethical research involving humans: ethical professional practice in impact assessment Part I

    National Research Council Canada - National Science Library

    Vanclay, Frank; Baines, James T; Taylor, C. Nicholas

    2013-01-01

    ... methods textbooks, this paper identifies current principles for ethical research involving humans and discusses their implications for impact assessment practice generally and social impact assessment specifically...

  18. THE SIXTH SENSE OF HUMAN?...

    Directory of Open Access Journals (Sweden)

    M.Arulmani, B.E

    2014-08-01

    Full Text Available Animals and lower animals do not have sixth Sense?... NO…NO….NO… All living organism as well as non-living organism considered also have 6th sense in gradient order. i. Which University mosquito studied to gain Techniques and cleverness to bite on the back beyond the reach of human hands?... ii. How the birds and Animals could predict the signals well in advance and move safely to other elevated places during “TSUNAMI 2004” Which human could not predict?... iii. How the pet dog could steel the chicken waste silently in the kitchen when owner under sleep?... iv. How honey bee, spider construct well defined knitted structure house?... This Scientific research article focus that not only human, all lower animals including Bacteria, Virus have “Intuition Sense” (Wisdom.

  19. [Neuroethics: Ethical Endowments of Human Brain].

    Science.gov (United States)

    López Moratalla, Natalia

    2015-01-01

    The neurobiological processes underlying moral judgement have been the focus of Neuroethics. Neurosciences demonstrate which cerebral areas are active and inactive whilst people decide how to act when facing a moral dilemma; in this way we know the correlation between determined cerebral areas and our human acts. We can explain how the ″ethical endowments″ of each person, common to all human beings, is ″embedded″ in the dynamic of cerebral flows. Of central interest is whether emotions play a causal role in moral judgement, and, in parallel, how emotion related areas of the brain contribute to moral judgement. The outcome of man's natural inclinations is on one hand linked to instinctive systems of animal survival and to basic emotions, and on the other, to the life of each individual human uninhibited by automatism of the biological laws, because he is governed by the laws of freedom. The capacity to formulate an ethical judgement is an innate asset of the human mind.

  20. Governing Nanotechnology: Social, Ethical and Human Issues

    Science.gov (United States)

    Bainbridge, William

    This chapter is a human-centered survey of nanotechnology's broader implications, reporting on the early phase of work by social scientists, philosophers, and other scholars. It begins with the social science agenda developed by governments, and the heritage of research on technology and organizations that social science brings to this mission. It then outlines current thinking about nanotechnology's economic impacts, health or environmental impacts, and social contributions. It discusses how technology can be regulated by a combination of informal ethics and formal law, then concludes by considering the shape of popular nanotechnology culture, as reflected in science fiction, public perceptions, and education.

  1. [Ethical principles in human scientific research].

    Science.gov (United States)

    Cruz-Coke, R

    1994-07-01

    Hippocrates was the first physician to use the scientific method to find rational and not religious or mythic causes, for the etiology of diseases. Hippocrates and Aristoteles did not dare to dissect the human body. Afterwards however, many scientists such as Herophilus, Erasitastrus, Vesalus and Fallopio, performed experiments in human beings using vivisection. According to that age's ideas, there was no cruelty in performing vivisection in criminals, since useful knowledge for the progress of medicine and relief of diseases was obtained. Only during the nineteenth century and with Claude Bernard (1865), the ethical principles of systematic scientific research in humans were defined. These principles were violated by nazi physicians during Hitler's dictatorship in Germany (1933-1945). As a response to these horrors, the Ethical Codes of Nuremberg (1947) and Geneva (1948), that reestablished all the strength of Hippocratic principles, were dictated. The Nuremberg rules enact that a research subject must give a voluntary consent, that the experiment must by necessary and exempt of death risk, that the research must be qualified and that the experiment must be discontinued if there is a risk for the subject. The Geneva statement is a modernized hippocratic oath that protects patient's life above all. These classical rules, in force at the present time, are the essential guides that must be applied by physicians and researchers.

  2. Developing a code of ethics for human cloning.

    Science.gov (United States)

    Collmann, J; Graber, G

    2000-01-01

    Under what conditions might the cloning of human beings constitute an ethical practice? A tendency exists to analyze human cloning merely as a technical procedure. As with all revolutionary technological developments, however, human cloning potentially exists in a broad social context that will both shape and be shaped by the biological techniques. Although human cloning must be subjected to technical analysis that addresses fundamental ethical questions such as its safety and efficacy, questions exist that focus our attention on broader issues. Asserting that cloning inevitably leads to undesirable consequences commits the fallacy of technological determinism and untenably separates technological and ethical evaluation. Drawing from the Report of the National Bioethics Advisory Committee and Aldous Huxley's Brave New World, we offer a draft "Code of Ethics for Human Cloning" in order to stimulate discussion about the ethics of the broader ramifications of human cloning as well as its particular technological properties.

  3. Basing Science Ethics on Respect for Human Dignity.

    Science.gov (United States)

    Aközer, Mehmet; Aközer, Emel

    2016-12-01

    A "no ethics" principle has long been prevalent in science and has demotivated deliberation on scientific ethics. This paper argues the following: (1) An understanding of a scientific "ethos" based on actual "value preferences" and "value repugnances" prevalent in the scientific community permits and demands critical accounts of the "no ethics" principle in science. (2) The roots of this principle may be traced to a repugnance of human dignity, which was instilled at a historical breaking point in the interrelation between science and ethics. This breaking point involved granting science the exclusive mandate to pass judgment on the life worth living. (3) By contrast, respect for human dignity, in its Kantian definition as "the absolute inner worth of being human," should be adopted as the basis to ground science ethics. (4) The pathway from this foundation to the articulation of an ethical duty specific to scientific practice, i.e., respect for objective truth, is charted by Karl Popper's discussion of the ethical principles that form the basis of science. This also permits an integrated account of the "external" and "internal" ethical problems in science. (5) Principles of the respect for human dignity and the respect for objective truth are also safeguards of epistemic integrity. Plain defiance of human dignity by genetic determinism has compromised integrity of claims to knowledge in behavioral genetics and other behavioral sciences. Disregard of the ethical principles that form the basis of science threatens epistemic integrity.

  4. Making Sense of Business Ethics - About Not Walking the Talk

    OpenAIRE

    Lindfelt, Lise-Lotte

    2006-01-01

    By using a sensemaking perspective, this article argues that it is not relevant to fully expect firms to walk their talk in ethical matters. Accuracy between words and deeds is utopia in a post-modern world, with chaos and complexity. Integrating diverse ways of doing ethical business across global regions rather creates legitimacy, trust and a good image among firms in business networks. So what is the role of the ethics code? The article gives examples from a case study on Stora En...

  5. Science, human nature, and a new paradigm for ethics education.

    Science.gov (United States)

    Lampe, Marc

    2012-09-01

    For centuries, religion and philosophy have been the primary basis for efforts to guide humans to be more ethical. However, training in ethics and religion and imparting positive values and morality tests such as those emanating from the categorical imperative and the Golden Rule have not been enough to protect humankind from its bad behaviors. To improve ethics education educators must better understand aspects of human nature such as those that lead to "self-deception" and "personal bias." Through rationalizations, faulty reasoning and hidden bias, individuals trick themselves into believing there is little wrong with their own unethical behavior. The application of science to human nature offers the possibility of improving ethics education through better self-knowledge. The author recommends a new paradigm for ethics education in contemporary modern society. This includes the creation of a new field called "applied evolutionary neuro-ethics" which integrates science and social sciences to improve ethics education. The paradigm can merge traditional thinking about ethics from religious and philosophical perspectives with new ideas from applied evolutionary neuro-ethics.

  6. Ethics education in advanced practice nursing: respect for human dignity.

    Science.gov (United States)

    Kalb, Kathleen A; O'Conner-Von, Susan

    2007-01-01

    Ethics education is an essential component of academic programs that prepare nurses for advanced practice; the concept of respect for human dignity is integral to this education. Sixty-three graduate students enrolled in their first course of a nurse practitioner program completed a researcher-developed Ethics Questionnaire that was designed to elicit their baseline ethics-related knowledge, including their understanding of the concept "respect for human dignity". Qualitative analysis of data yielded findings that validate the importance of using the American Nurses Association Code of Ethics for Nurses with Interpretive Statements as an essential foundation for ethics content and as a framework for understanding the meaning of human dignity in advanced practice nursing. Assessment and learning strategies are recommended.

  7. Ethical Issues in the Use of Humans for Research.

    Science.gov (United States)

    Bashaw, W. L.

    The APA Ethical Principles, the University of Georgia policy, standard research texts, and research literature on specific methodologies, all in relation to ethical issues in human research, are discussed. The 10 APA principles state, in essence, that the investigator is responsible for what happens, that confidentiality and the protection of the…

  8. ON THE ETHICS OF HUMAN DIGNITY IN TODAY'S CHANGING WORLD

    Directory of Open Access Journals (Sweden)

    VOROPAEVA Y.P.

    2012-01-01

    Full Text Available The article indicates the relevance of considering the ethics of human dignity in modern globalized world. Due to the fact that the basis of understanding of the new world is its recognition as a whole, there’s an important question of researching new supranational values ​​ where the fundamental value is the ethical category of «human dignity».

  9. Psihologie, morală, politică: avatarurile umanismului (Psychology, ethic, politics: the avatars of humanism

    Directory of Open Access Journals (Sweden)

    Alexandru MAMINA

    2016-06-01

    Full Text Available The article treats the impact of psychological researches upon the humanistic ethic came out from Lumières, and subsequently on the liberal thought influenced by that. Hence it first presents the crisis which psychoanalysis induced to the traditional image of human being as rational an capable of free will. It also shows the way that humanistic view was transformed and so recovered in a more democratic sense by the analytical psychology and mainly the cultural psychoanalysis.

  10. Ethical issues regarding human cloning: a nursing perspective.

    Science.gov (United States)

    Dinç, Leyla

    2003-05-01

    Advances in cloning technology and successful cloning experiments in animals raised concerns about the possibility of human cloning in recent years. Despite many objections, this is not only a possibility but also a reality. Human cloning is a scientific revolution. However, it also introduces the potential for physical and psychosocial harm to human beings. From this point of view, it raises profound ethical, social and health related concerns. Human cloning would have an impact on the practice of nursing because it could result in the creation of new physiological and psychosocial conditions that would require nursing care. The nursing profession must therefore evaluate the ethics of human cloning, in particular the potential role of nurses. This article reviews the ethical considerations of reproductive human cloning, discusses the main reasons for concern, and reflects a nursing perspective regarding this issue.

  11. Ethical issues in human reproduction: Islamic perspectives.

    Science.gov (United States)

    Serour, G I

    2013-11-01

    Sexual and reproductive rights of women are essential components of human rights. They should never be transferred, renounced or denied for any reason based on race, religion, origin, political opinion or economic conditions. Women have the right to the highest attainable standard of health care for all aspects of their reproductive and sexual health (RSH). The principle of autonomy emphasizes the important role of women in the decision-making. Choices of women in reproduction, after providing evidence based information, should be respected. Risks, benefits and alternatives should be clearly explained before they make their free informed consent. Justice requires that all be treated with equal standard and have equal access to their health needs without discrimination or coercion. When resources are limited there is tension between the principle of justice and utility. Islamic perspectives of bioethics are influenced by primary Sharia namely the Holy Quran, authenticated traditions and saying of the Profit Mohamed (PBUH), Igmaa and Kias (analogy). All the contemporary ethical principles are emphasized in Islamic Shariaa, thus these principles should be observed when providing reproductive and sexual health services for Muslim families or communities. The Family is the basic unit in Islam. Safe motherhood, family planning, and quality reproductive and sexual health information and services and assisted reproductive technology are all encouraged within the frame of marriage. While the Shiaa sect permits egg donation, and surrogacy the Sunni sect forbids a third party contribution to reproduction. Harmful practices in RSH as FGM, child marriage and adolescent pregnancy are prohibited in Islam. Conscientious objection to treatment should not refrain the physician from appropriate referral.

  12. The ethics of human genetic intervention: a postmodern perspective.

    Science.gov (United States)

    Dyer, A R

    1997-03-01

    Gene therapy for a particular disease like Parkinson's involves ethical principles worked out for other diseases. The major ethical issues for gene therapy (and the corresponding ethical principles) are safety (nonmalfeasance), efficacy (beneficence), informed consent (autonomy), and allocation of resources (justice). Yet genetic engineering (germ-line interventions or interventions to enhance human potentialities) raises emotions and fears that might cause resistance to gene therapies. Looking at these technologies in a postmodern perspective helps one to appreciate the issues at stake in social and cultural change with a new technology such as gene therapy. While "modern" technology and ethics have focused on the autonomy of the individual, we are beginning to see a lessening of such emphasis on individualism and autonomy and more emphasis on the health of the population. Such a social change could cause technologies about which society may currently be cautious (such as human genetic interventions) to become more acceptable or even expected.

  13. Sensing Super-Position: Human Sensing Beyond the Visual Spectrum

    Science.gov (United States)

    Maluf, David A.; Schipper, John F.

    2007-01-01

    The coming decade of fast, cheap and miniaturized electronics and sensory devices opens new pathways for the development of sophisticated equipment to overcome limitations of the human senses. This paper addresses the technical feasibility of augmenting human vision through Sensing Super-position by mixing natural Human sensing. The current implementation of the device translates visual and other passive or active sensory instruments into sounds, which become relevant when the visual resolution is insufficient for very difficult and particular sensing tasks. A successful Sensing Super-position meets many human and pilot vehicle system requirements. The system can be further developed into cheap, portable, and low power taking into account the limited capabilities of the human user as well as the typical characteristics of his dynamic environment. The system operates in real time, giving the desired information for the particular augmented sensing tasks. The Sensing Super-position device increases the image resolution perception and is obtained via an auditory representation as well as the visual representation. Auditory mapping is performed to distribute an image in time. The three-dimensional spatial brightness and multi-spectral maps of a sensed image are processed using real-time image processing techniques (e.g. histogram normalization) and transformed into a two-dimensional map of an audio signal as a function of frequency and time. This paper details the approach of developing Sensing Super-position systems as a way to augment the human vision system by exploiting the capabilities of Lie human hearing system as an additional neural input. The human hearing system is capable of learning to process and interpret extremely complicated and rapidly changing auditory patterns. The known capabilities of the human hearing system to learn and understand complicated auditory patterns provided the basic motivation for developing an image-to-sound mapping system. The

  14. Militarism, human welfare, and the APA Ethical Principles of Psychologists.

    Science.gov (United States)

    Summers, Craig

    1992-01-01

    A case study is presented of the American Psychological Association (APA), as a health care organization that promotes human welfare. APA includes policies on human welfare in its Ethical Principles of Psychologists and even lists the advancement of psychology "as a means of promoting human welfare" on its letterhead. Nevertheless, APA has other policies and activities based on military and weapons work that appear to conflict with its promotion of human welfare. Although military work in and of itself may not necessarily be problematic, work that contributes to people purposely being harmed or killed should be squared with the association's ethical guidelines. The results presented here show that this may not be the case: There currently appears to be little justification in the Ethical Principles for work intended to harm people. APA's active lobbying, research, and development for the military are documented here, in relation to an analysis of the Ethical Principles. APA's uncritical support for Operation Desert Storm is examined specifically, with regard to weapons technology and therapeutic treatment of U.S. soldiers on the battlefield. This one-sided support for victims of the war is not in keeping with a Hippocratic health care ethic to treat patients needing care, and to do so with neutrality and impartiality. Similarities to a historical example of nationalistic mental health ethics are discussed, with a review of the development of the German Institute for Psychological Research and Psychotherapy and of the German Society for Psychology in the Nazi wartime effort and the Holocaust. The results here show similar deficiencies in APA's ethical standards, not the least of which is that the code applies to individual members but not to APA policies, committees, or activities. This article concludes with suggested criteria for the Ethical Principles that would at least (a) recognize the ambiguities in systematically developing and using weapons to hurt people

  15. Justice in human research ethics. A conceptual and practical guide.

    Science.gov (United States)

    Pieper, Ian; Thomson, Colin J H

    2013-03-01

    One of the core values to be applied by a body reviewing the ethics of human research is justice. The inclusion of justice as a requirement in the ethical review of human research is relatively recent and its utility had been largely unexamined until debates arose about the conduct of international biomedical research in the late 1990s. The subsequent amendment of authoritative documents in ways that appeared to shift the meaning of conceptions of justice generated a great deal of controversy. Another difficulty has been that both the theory and the substance of justice that are applied by researchers or reviewers can be frequently seen to be subjective. Both the concept of justice--hether distributive or commutative--and what counts as a just distribution or exchange--are given different weight and meanings by different people. In this paper, the origins and more recent debates about the requirement to consider justice as a criterion in the ethical review of human research are traced, relevant conceptions of justice are distinguished, and the manner in which they can be applied meaningfully in the ethical review of all human research is identified. We also explain the way that these concepts are articulated in, and the intent and function of, specific paragraphs of the National Statement on Ethical Conduct in Human Research (2007). The National Statement identifies a number of issues that should be considered when a human research ethics committee is reviewing the justice aspects of an application. We provide guidance to researchers as to how they can show that there is a fair distribution of burdens and benefits in the participant experience and the research outcomes. We also provide practical guidance to researches on how to think through issues of justice so that they can demonstrate that the design of their research projects meets this ethical requirement.

  16. [Ethical considerations on human cloning. A psychoanalytic perspective].

    Science.gov (United States)

    Alvarez, A

    2000-01-01

    A brief review of ethical issues related to two types of human cloning is presented: cloning embryonic cells not intended to culminate in the birth of a new individual and cloning human beings. Advantages and objections related to both types of human cloning are analyzed from an ethical point of view. Repercussions on individuals born by the technique of cloning are discussed from a psychoanalytical perspective. It can be concluded that cloning embryonic cells could be admissible, while not cloning considered as a reproductive option.

  17. Ethics, standards, and procedures of animal and human chronobiology research.

    Science.gov (United States)

    Touitou, Yvan; Smolensky, Michael H; Portaluppi, Francesco

    2006-01-01

    The majority of research papers published in Chronobiology International report the findings of investigations conducted on laboratory animals and human beings. The editors and the readers of the journal expect the authors of submitted manuscripts to have made an important contribution to biological rhythm and related research through the ethical conduct of investigations and unbiased and accurate reporting of findings. Authors of scientific papers are required to disclose any potential conflict of interest. The journal accepts only papers that are original work, no part of which has been submitted for publication elsewhere, except as brief abstracts. The journal and its editors endorse the compliance of investigators to the principles of the Declaration of Helsinki of the World Medical Association, which relate to the conduct of ethical research on human beings, and the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council, which relate to the conduct of ethical research on laboratory and other animals. The peer review of manuscripts by Chronobiology International thus includes judgment as to whether or not the investigative methods conform to the standards of good research practice. This article updates the ethical policies, standards, and procedures for manuscripts submitted to Chronobiology International that involve human and animal biological rhythm research, both from the perspective of the criteria of quality chronobiology investigation and from the perspective of humane and ethical research on human beings and animals.

  18. Science Fiction, Ethics and the Human Condition

    DEFF Research Database (Denmark)

    Baron, Christian; Halvorsen, Peter Nicolai; Cornea, Christine

    . Further, those with a concern for the future may find inspiration in what a study of the politics and ethics of science fiction can tell us about the moral and political dilemmas of our own time. Although this book is more likely to be picked up by someone who already has an interest in science fiction...

  19. Medical ethics and human rights in wartime

    African Journals Online (AJOL)

    2015-03-09

    Mar 9, 2015 ... Dr Wouter Basson was charged with violating this medical ethics norm during the ... a criminal trial, with a higher standard of proof than a civil trial ... cannot escape responsibility by relying on a military order; that as long as a ...

  20. Environmental Health Research Involving Human Subjects: Ethical Issues

    Directory of Open Access Journals (Sweden)

    David B. Resnik

    2008-01-01

    Full Text Available This article reviews some of the ethical issues that arise in environmental health research with human subjects, such as minimizing risks to subjects, balancing benefits and risks in research, intentional exposure studies with human subjects, protecting third parties in research, informing subjects about environmental hazards, communicating health information to subjects, and protecting privacy and confidentiality.

  1. Ethics, religion and humanity: Rethinking religion in 21 st century ...

    African Journals Online (AJOL)

    Ethics, religion and humanity: Rethinking religion in 21 st century Africa. ... AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL · RESOURCES ... First and foremost, religion is a human activity. ... results of inhuman and unethical practices in religion and that these problems can be minimized ...

  2. [Ethics, inequality, poverty and human rights in psychiatry].

    Science.gov (United States)

    Pérez De Nucci, Armando M

    2007-01-01

    This article aims to show the existence of important failures in the field of Human Rights and equal possibilities in health. Human rights are analyzed an developed in the field of public and social health in our country. Ethics is the main field proposed to reach solutions in the context on EPEP (Etica para la erradicación de la pobreza).

  3. A Selected Review of the Underpinnings of Ethics for Human Performance Technology Professionals--Part One: Key Ethical Theories and Research.

    Science.gov (United States)

    Dean, Peter J.

    1993-01-01

    Provides a review of the key ethical theories and relevant empirical research relating to the practice of human performance technology. Topics addressed include ethics, morals, business ethics, ethics officers, empiricism versus normative ethical theory, consequentialism, utilitarianism, nonconsequentialism, Kohlberg model of cognitive moral…

  4. A Selected Review of the Underpinnings of Ethics for Human Performance Technology Professionals--Part One: Key Ethical Theories and Research.

    Science.gov (United States)

    Dean, Peter J.

    1993-01-01

    Provides a review of the key ethical theories and relevant empirical research relating to the practice of human performance technology. Topics addressed include ethics, morals, business ethics, ethics officers, empiricism versus normative ethical theory, consequentialism, utilitarianism, nonconsequentialism, Kohlberg model of cognitive moral…

  5. Creating a Controlled Vocabulary for the Ethics of Human Research: Towards a Biomedical Ethics Ontology

    Science.gov (United States)

    Koepsell, David; Arp, Robert; Fostel, Jennifer; Smith, Barry

    2009-01-01

    Ontologies describe reality in specific domains in ways that can bridge various disciplines and languages. They allow easier access and integration of information that is collected by different groups. Ontologies are currently used in the biomedical sciences, geography, and law. A Biomedical Ethics Ontology (BMEO) would benefit members of ethics committees who deal with protocols and consent forms spanning numerous fields of inquiry. There already exists the Ontology for Biomedical Investigations (OBI); the proposed BMEO would interoperate with OBI, creating a powerful information tool. We define a domain ontology and begin to construct a BMEO, focused on the process of evaluating human research protocols. Finally, we show how our BMEO can have practical applications for ethics committees. This paper describes ongoing research and a strategy for its broader continuation and cooperation. PMID:19374479

  6. Ethical fundamentals in human subjects research : On equipoise and human dignity

    NARCIS (Netherlands)

    van der Graaf - Verhave, R.|info:eu-repo/dai/nl/304821373

    2010-01-01

    In her PhD thesis Rieke van der Graaf has studied how we can ethically justify human subjects research. In particular she has studied two ethical fundamentals that play a key role in the justification process, that of equipoise and human dignity. Equipoise is often taken to mean that

  7. Ethical fundamentals in human subjects research : On equipoise and human dignity

    NARCIS (Netherlands)

    van der Graaf - Verhave, R.

    2010-01-01

    In her PhD thesis Rieke van der Graaf has studied how we can ethically justify human subjects research. In particular she has studied two ethical fundamentals that play a key role in the justification process, that of equipoise and human dignity. Equipoise is often taken to mean that physician-resea

  8. Ethical regulation or regulating ethics? The need for both internal and external governance of human experimentation.

    Science.gov (United States)

    Tomossy, George F

    2002-10-01

    Research regulation is a timely topic for discussions in bioethics and public health policy. This response to articles in the previous special issue of the Monash Bioethics Review emphasises the importance of having both internal and external controls on human experimentation. Unless both elements are incorporated into research ethics governance frameworks, they will ultimately fail to achieve what should be their primary goal: human subject protection.

  9. Human embryonic stem cell research: ethical and legal issues.

    Science.gov (United States)

    Robertson, J A

    2001-01-01

    The use of human embryonic stem cells to replace damaged cells and tissues promises future hope for the treatment of many diseases. However, many countries now face complex ethical and legal questions as a result of the research needed to develop these cell-replacement therapies. The challenge that must be met is how to permit research on human embryonic tissue to occur while maintaining respect for human life generally.

  10. Dolphin natures, human virtues: MacIntyre and ethical naturalism.

    Science.gov (United States)

    Glackin, Shane Nicholas

    2008-09-01

    Can biological facts explain human morality? Aristotelian 'virtue' ethics has traditionally assumed so. In recent years Alasdair MacIntyre has reintroduced a form of Aristotle's 'metaphysical biology' into his ethics. He argues that the ethological study of dependence and rationality in other species--dolphins in particular--sheds light on how those same traits in the typical lives of humans give rise to the moral virtues. However, some goal-oriented dolphin behaviour appears both dependent and rational in the precise manner which impresses MacIntyre, yet anything but ethically 'virtuous'. More damningly, dolphin ethologists consistently refuse to evaluate such behaviour in the manner MacIntyre claims is appropriate to moral judgement. In light of this, I argue that virtues--insofar as they name a biological or ethological category--do not name a morally significant one.

  11. [From Nuremberg to the ethics committees in human experimentation].

    Science.gov (United States)

    Demarez, Jean-Paul

    2008-02-01

    During the Nuremberg trials, the accusation prompted the creation of an ad hoc committee to advise on human experiments carried out on prisoners during wartime in the USA. Precisely a charge that had been brought against Karl Brandt and his colleagues. This committee was the forerunner of the Independent Committees, to which the Declaration of Helsinki assigned a role in analysing the ethics of research projects in humans. From 1980 onwards, in industrialised countries, the legislation regarding clinical trials began to incorporate similar structures, IRBs in the United States of America, Ethics Committees elsewhere, and the ''Committee for the Protection of Persons" in France. However, at that time, in spite of the misleading words, we went from ethics to law, from rules of conduct intended for researchers to legal regulations organising relations between sponsors, investigators and persons participating in biomedical research, which is not the same thing.

  12. Philanthropy and Human Rights in Business Ethics

    DEFF Research Database (Denmark)

    Larsen, Øjvind

    2017-01-01

    Philanthropy has become a concern which is taken seriously in the Western world. Normal people give donations and volunteer on a large scale within the institutions of civil society. This is the case for business corporations as well in the big global CSR movement, which has now been integrated...... in the UN Global Compact. Philanthropy has many dimensions; these include ethical, juridical, political, economic and cultural dimensions. In the last years, a lot has been written about philanthropy from a political, sociological, anthropological and managerial perspective. However, an essential question...

  13. [Ethical aspects of human lactation and breastfeeding].

    Science.gov (United States)

    Parrilla Rodríguez, A M; Gorrín Peralta, J J

    2000-06-01

    Breastfeeding has experienced a surge in Puerto Rico thanks to the efforts of many women, as well as governmental, non-governmental and private organizations. Among the aspects which can affect the initiation, establishment and maintenance of successful breastfeeding one finds potential ethical conflicts among health professionals as well as the financial interests of the companies which produce and market artificial milks. These companies dedicate great marketing efforts and enormous sums of money in the sale of their products, in detriment of breastfeeding. The profit motive of these companies is in open contradiction to public health and to breastfeeding promotion. The international community has carried out efforts for more than two decades in the creation of structures which protect the rights of women and their children to ideal nutrition practices, free from commercial pressures, through breastfeeding. Possible ethical conflicts related to the new industry of breastfeeding paraphernalia are discussed, especially when these are marketed exclusively for profit. Recommendations are presented for health professionals in order for them to be able to face and respond to the unethical strategies practiced by the manufacturers of artificial milks in utilizing these professionals for legitimating and marketing their products.

  14. Human dignity and biomedical ethics from a Christian theological ...

    African Journals Online (AJOL)

    2011-07-11

    Jul 11, 2011 ... based on human dignity in bioethics and in biomedical ethics is obsolete in general. .... on the one side and those concerned with Germany as a location for business and ..... charity includes a duty to heal. This command is ...

  15. Developing a Working Code of Ethics for Human Resource Personnel.

    Science.gov (United States)

    Rampal, Kuldip R.

    1991-01-01

    To develop codes of ethics for their profession, college human resources personnel must first understand their primary job-related responsibilities. These include being alert to evolving organizational needs; coordinating needed training of employees; appreciating the nuances of psychology, communication, and motivation; and observing employee…

  16. The ethics of human-robot relationships

    NARCIS (Netherlands)

    Graaf, de Maartje M.A.

    2015-01-01

    Currently, human-robot interactions are constructed according to the rules of human-human interactions inviting users to interact socially with robots. Is there something morally wrong with deceiving humans into thinking they can foster meaningful interactions with a technological object? Or is this

  17. TRAINING IN ETHICS OF HUMAN CAPITAL TO BUSINESS DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Neyda Ibañez

    2009-04-01

    Full Text Available The purpose of the investigation was to interpret training in ethics for action business students an introduction to the economy of the Faculty of Social and Economic Sciences at the University of Carabobo, as part of professional development in business studies. The investigation was addressed within the paradigm post positivist using ethnographic and hermeneutic method, descriptive mode of scientific research and technique participant-observation. It concludes that training in ethics management must transcend the economic theories located in the teleological by financial or economic interests toward the teleological including humanism.

  18. [Establishing and operating a human biobank. Ethical aspects].

    Science.gov (United States)

    Jahns, Roland

    2016-03-01

    Particularly in the past decade which has been marked by efforts to foster individualized/personalized medicine the need for well-characterized high-quality collections of human biological material has significantly increased. When establishing and operating a human biobank the interests and the "freedom" of biomedical research must always be weighed against the interests and rights of patients and/or donors; in this process ethical aspects should be considered systematically. In addition, the importance of quality control and quality assurance has largely increased in human biobanking, both from a scientific and even more from an ethical point of view, because donated biological materials are potentially stored for decades and (on request) might serve for currently not foreseeable biomedical research purposes. In addition, the compatibility of national human biobanks with international biobank networks becomes increasingly important.

  19. Metaphysical and ethical perspectives on creating animal-human chimeras.

    Science.gov (United States)

    Eberl, Jason T; Ballard, Rebecca A

    2009-10-01

    This paper addresses several questions related to the nature, production, and use of animal-human (a-h) chimeras. At the heart of the issue is whether certain types of a-h chimeras should be brought into existence, and, if they are, how we should treat such creatures. In our current research environment, we recognize a dichotomy between research involving nonhuman animal subjects and research involving human subjects, and the classification of a research protocol into one of these categories will trigger different ethical standards as to the moral permissibility of the research in question. Are a-h chimeras entitled to the more restrictive and protective ethical standards applied to human research subjects? We elucidate an Aristotelian-Thomistic metaphysical framework in which to argue how such chimeras ought to be defined ontologically. We then examine when the creation of, and experimentation upon, certain types of a-h chimeras may be morally permissible.

  20. Human enhancement from ethical interrogations to legal (un)certainty

    DEFF Research Database (Denmark)

    Nordberg, Ana

    2016-01-01

    Emerging technologies are paving the way for future revolutionary advances in science that may open the possibility to change the very anthropological definition of human being. This mere possibility has lead to ethical interrogations concerning the nature and boundaries of human nature and our...... relationship with science and technology. Meanwhile the Law has faced the challenge of reflecting on the legitimacy to legislate and whether the existing legal framework is appropriate to address the ethical concerns that emerging technologies bring fourth. It is a delicate balancing act between human dignity......, autonomy, non-discrimination, equality, and justice. Anchored in this background, this work is a reflection on the role of European Patent Law in this debate. The European Patent system contains rules designed to prevent the grant of patents concerning inventions that do not conform to the prevailing...

  1. Physician Encounters with Human Trafficking: Legal Consequences and Ethical Considerations.

    Science.gov (United States)

    Todres, Jonathan

    2017-01-01

    There is growing recognition and evidence that health care professionals regularly encounter-though they may not identify-victims of human trafficking in a variety of health care settings. Identifying and responding appropriately to trafficking victims or survivors requires not only training in trauma-informed care but also consideration of the legal and ethical issues that arise when serving this vulnerable population. This essay examines three areas of law that are relevant to this case scenario: criminal law, with a focus on conspiracy; service provider regulations, with a focus on mandatory reporting laws; and human rights law. In addition to imposing a legal mandate, the law can inform ethical considerations about how health care professionals should respond to human trafficking.

  2. Reflections on Ethics and Humanity in Pediatric Neurology: the Value of Recognizing Ethical Issues in Common Clinical Practice.

    Science.gov (United States)

    Ronen, Gabriel M; Rosenbaum, Peter L

    2017-05-01

    Our goals in this reflection are to (i) identify the ethical dimensions inherent in any clinical encounter and (ii) bring to the forefront of our pediatric neurology practice the myriad of opportunities to explore and learn from these ethical questions. We highlight specifically Beauchamp and Childress's principles of biomedical ethics. We use the terms ethics in common clinical practice and an ethical lens to remind people of the ubiquity of ethical situations and the usefulness of using existing ethical principles to analyze and resolve difficult situations in clinical practice. We start with a few common situations with which many of us tend to struggle. We describe what we understand as ethics and how and why developments in technology, novel potential interventions, policies, and societal perspectives challenge us to think about and debate ethical issues. Individual patients are not a singular population; each patient has their own unique life situations, culture, goals, and expectations that need to be considered with a good dose of humanity and humility. We believe that using an ethical lens-by which we mean making an explicit effort to identify and consider these issues openly-will help us to achieve this goal in practice, education, and research.

  3. Cloning humans? Biological, ethical, and social considerations.

    Science.gov (United States)

    Ayala, Francisco J

    2015-07-21

    There are, in mankind, two kinds of heredity: biological and cultural. Cultural inheritance makes possible for humans what no other organism can accomplish: the cumulative transmission of experience from generation to generation. In turn, cultural inheritance leads to cultural evolution, the prevailing mode of human adaptation. For the last few millennia, humans have been adapting the environments to their genes more often than their genes to the environments. Nevertheless, natural selection persists in modern humans, both as differential mortality and as differential fertility, although its intensity may decrease in the future. More than 2,000 human diseases and abnormalities have a genetic causation. Health care and the increasing feasibility of genetic therapy will, although slowly, augment the future incidence of hereditary ailments. Germ-line gene therapy could halt this increase, but at present, it is not technically feasible. The proposal to enhance the human genetic endowment by genetic cloning of eminent individuals is not warranted. Genomes can be cloned; individuals cannot. In the future, therapeutic cloning will bring enhanced possibilities for organ transplantation, nerve cells and tissue healing, and other health benefits.

  4. Human genome and open source: balancing ethics and business.

    Science.gov (United States)

    Marturano, Antonio

    2011-01-01

    The Human Genome Project has been completed thanks to a massive use of computer techniques, as well as the adoption of the open-source business and research model by the scientists involved. This model won over the proprietary model and allowed a quick propagation and feedback of research results among peers. In this paper, the author will analyse some ethical and legal issues emerging by the use of such computer model in the Human Genome property rights. The author will argue that the Open Source is the best business model, as it is able to balance business and human rights perspectives.

  5. [Triploid cloned human embryos: ethical, social, and legal aspects].

    Science.gov (United States)

    Bellver Capella, Vicente

    2012-01-01

    This work attempts to place the experiment within the scientific and social framework of pluripotent-stem-cell research and offer reflections of an ethical and (to a lesser extent) legal nature on the results obtained by this research group. To these ends, the work is divided into two parts. The first part describes the most important aspects of Noggle and Egli's announcement and the biotechnological and media context in which it was made. The second part is concerned with the bioethical issues raised by the experiment. There are basically four issues, which relate to: (1) the nuclear transfer technique, (2) the use of human ovules to carry out the experiment, (3) the destruction of human blastocysts, and (4) the ethical requirements of scientific publications.

  6. [AIDS: ethics and scientific investigation on human beings].

    Science.gov (United States)

    Guedj, R

    2008-04-01

    The experimentation on human beings of one or several therapeutic molecules discovered in laboratory is necessary and important because it helps to find new treatments or new diagnostic methods. But, it presents serious ethical problems. In this article we are analysing the example of the HIV infection. We are succinctly describing the research methods in laboratory for therapeutic molecules, first the experimentation on animals and then on human being in clinical trials. We will then try to show, with several examples, how during these last 25 years of HIV infection, the research of new molecules has not always respected the ethical rules set out in Helsinki declaration, "Code de la santé publique" or "Guide de bonnes pratiques cliniques-ICH" etc. We are discussing here the way to avoid these irregularities.

  7. Human resources: a common-sense discipline.

    Science.gov (United States)

    Courtney, Lisa R

    2004-02-01

    Being able to hire the right team members, keeping them engaged ina professional and productive environment, and avoiding litigation help keep the team functioning and meeting the everyday goals of providing quality patient care. Although these topics may seem complex, medical providers and professionals have resources available to them, such as the Human Resources department, the Medical Director, senior management,and legal counsel. Hiring the right people, creating a positive work environment, and avoiding litigation are all common sense principals that are relevant regardless of profession, industry, or company. Understanding how to apply the principles and concepts of Human Resources and personnel management can seem overwhelming: however, asking for help from the resources mentioned previously and applying the common sense information found in this article will help one to be a successful leader and practitioner.

  8. ETHICS IN HEALTH CARE: INDUCEMENT AND HUMAN SUBJECTS

    Directory of Open Access Journals (Sweden)

    MUNIR HOSSAIN TALUKDER

    2011-05-01

    Full Text Available Currently, most health researchers or donor organizations considerinducement as a vital part in promoting research. They propose benefits, such as post research free medical treatment, food, insurance facilities, or even cash, in order to meet sufficient number of subjects. So, inducement may influence one to participate in a research. Is it ethical to offer inducement to human subjects? What are the risks in such practice? What will happen if the donor agencies use subjects by hiding possible risks from them? When an inducement can satisfy ethical criteria? The CIOMS, FDA, and other ethical guidelines hold that inducement is unethical because it involves enough risk for voluntary informed consent. Supporting this position, a group of ethicists has argued that inducement undermines voluntariness especially when subjects are poor and vulnerable, and thus, unethical. In contrast to them, others argue that inducement contributes to discover new knowledge which can improve miserable condition of the poor. In their view, an inducement maintains all ethical criteria including subject’s autonomy, and therefore, morally permissible. The paper focuses this debate and analyzes both types ofargument. It examines whether inducement invalidate informed consent.Even if inducement may not violate the basic components of informedconsent, the paper concludes, subjects may claim a prima facie right to enjoy research outcomes.

  9. Public health ethics and more-than-human solidarity.

    Science.gov (United States)

    Rock, Melanie J; Degeling, Chris

    2015-03-01

    This article contributes to the literature on One Health and public health ethics by expanding the principle of solidarity. We conceptualise solidarity to encompass not only practices intended to assist other people, but also practices intended to assist non-human others, including animals, plants, or places. To illustrate how manifestations of humanist and more-than-human solidarity may selectively complement one another, or collide, recent responses to Hendra virus in Australia and Rabies virus in Canada serve as case examples. Given that caring relationships are foundational to health promotion, people's efforts to care for non-human others are highly relevant to public health, even when these efforts conflict with edicts issued in the name of public health. In its most optimistic explication, One Health aims to attain optimal health for humans, non-human animals and their shared environments. As a field, public health ethics needs to move beyond an exclusive preoccupation with humans, so as to account for moral complexity arising from people's diverse connections with places, plants, and non-human animals.

  10. How to challenge a culturalization of human existence? Promoting interculturalism and ethical thinking in education

    Directory of Open Access Journals (Sweden)

    Frédérique Brossard Børhaug

    2016-04-01

    Full Text Available What if culture appears to be a universal solution – and problem – to all human encounters in the multicultural school? When teachers explain the problems encountered by minority pupils simply by reference to their cultural (religious backgrounds, one faces the danger of culturalization where the other’s difference is explained only by his/her ethnicity. Culturalization is highly problematic because it emphasizes stereotyped inter-group differences and by doing so erases intra-group and inter-individual differences. The article argues that culture is fundamental in human existence, but it should not be an ambiguous dimension if the school seeks to help the learner get a stronger capacity of voice and aspiration. In order to challenge culturalization of human existence, it is crucial for education to promote the paradigm of interculturalism. Such a paradigm requires educators to acknowledge multiple forms of identity belongings for the individual and to resist the interpretation of culture as common sense. Education becomes intercultural and provides liberating categorizations for the individual when it acknowledges the true value of chosen cultural affiliations and individual aspirations. Nonetheless, promoting interculturalism might not be sufficient. Facing the potential danger of culturalization, we also need to foster ethics in education, in order to deconstruct the categories of cultural identity and belonging. Drawing on the philosophy of Emmanuel Levinas (1905-1995 the article argues that loving the other implies the act of loving the other person as a brother and as a stranger. Responsibility understood as an ethical responsibility opens up the community’s traditional structures and promotes a politics of ethical difference. Justice, thus, is not only about how well rights and duties are enforced, but also a matter of the other’s right to be other. Difference as a category is in other words not cultural but refers to the

  11. Humanizing business : a modern virtue ethics approach.

    OpenAIRE

    Moore, G.

    2005-01-01

    The paper begins by exploring whether a "tendency to avarice" exists in most capitalist business organisations. It concludes that it does and that this is problematic. The problem centres on the potential threat to the integrity of human character and the disablement of community. What, then, can be done about it? Building on previous work (Moore, 2002) in which Macintyre's notions of practice and institution were explored (Maclntyre, 1985), the paper offers a philosophically based argument i...

  12. The ethics of cloning and human embryo research.

    Science.gov (United States)

    Saran, Madeleine

    2002-01-01

    The successful cloning experiments that led to Dolly in 1997 have raised many ethical and policy questions. This paper will focus on cloning research in human embryonic cells. The possible gains of the research will be judged against the moral issues of doing research on a person. This paper concludes that while the embryo has some moral status, its moral status is outweighed by the multitude of benefits that embryonic stem cell research will bring to humanity. Policy suggestions are given for dealing with this new and developing field of stem cell research.

  13. Ethical Conduct in Research Involving Human Beings In Brazil

    Science.gov (United States)

    Novaes, Maria Rita Garbi; Guilhem, Dirce; Lolas, Fernando

    2010-01-01

    Objective Diagnose ethical conduct in research involving human beings in Brazil and the last 10 years of activity by the Human Research Ethics Committee of the Health Department - Federal District - CEP/SES/DF. Methods This work was based on a documentary research, descriptive and retrospective. It examined the database containing records of cases brought before the CEP/SES/DF, corresponding the period of June 1997 to December 2007. Results were generated in Excel program, version 2007. Results CEP/SES/DF has presented increasing number of research projects submitted to appreciation (n = 1129), composing: 90.4% approved 1.7% disapproved, 7.4% removed/filed and 0.5% excluded. Of these projects, 83% belonged to Group III, 18% multi-centered projects and 10% protocols with foreign participation. Time for approval has decreased over the years (30 to 60 days). Frequent pendencies: End of Free and Informed Consent (30%), Cover Sheet (25%), Methodology (20%), Curriculum vitae (12%), Budget (9%), and Others (4%). Conclusion The assessment of the CEP/SES/DF activities, during a ten-year period has shown its commitment to the legitimacy of research ethics review and scientific production SES/DF. There were some weaknesses such as difficulty in monitoring the accompaniment of the research; interruption of works due to adverse drug reaction; gaps or errors in the protocol submitted by the researcher. These situations are the achieving targets for the elaboration of specific criteria. PMID:20981277

  14. The economics and ethics of markets for human organs.

    Science.gov (United States)

    Hansmann, H

    1989-01-01

    In 1984, federal legislation outlawing payment for human organs for transplantation was adopted after only cursory discussion of the underlying policy issues. More considered analysis suggests that this prohibition may be overly broad. It appears possible to design suitably regulated market-type approaches to the acquisition and allocation of cadaveric organs (and perhaps of organs from living donors as well) that will be neither unduly offensive to ethical sensibilities nor easily abused and that may yield significant improvements over the existing system of organ procurement, which presents important ethical and practical problems of its own. Moreover, whatever ultimate judgment we reach concerning the merits of markets for transplantable organs, analysis of the sources of the initial moral resistance to the commercialization that lies behind measures such as the 1984 legislation offers insights into the respective roles of market and nonmarket institutions in general.

  15. Patenting human pluripotent cells: balancing commercial, academic and ethical interests.

    Science.gov (United States)

    Bahadur, G; Morrison, M

    2010-01-01

    The article addresses the issue of the ethics of patenting in human embryonic stem (hES) cells. The current stance of the European Patent Office in citing moral objections to patents on hES cells and the monopolistic scope of the Wisconsin Research Alumni Fund/Geron patents granted by the United States Patent and Trademark Office represent twin obstacles to achieving an ethical balance in patent rights in this field. The particular issues and strategies around granting patents on hES cells can be better understood by placing them in the context of the biotechnology industry and its role in the global bioeconomy. Some possible avenues of redress are considered based on the potential to open up cell pluripotency as new terrain for intellectual property offered by new technological breakthroughs such as induced pluripotent cells. Any changes in patent law should be accompanied by increased collaboration through devices such as patent pools.

  16. Use of Human Senses as Sensors

    Directory of Open Access Journals (Sweden)

    Yoshiaki Sugawara

    2009-04-01

    Full Text Available This paper is an overview of our recent findings obtained by the use of human senses as sensors, suggesting that human senses might be indispensable sensors, not only for practical uses but also for gaining a deeper understanding of humans. From this point of view, two kinds of studies, both based on semantic responses of participants, deserve emphasis. One study assessed the efficacy of the photocatalytic elimination of stains or bio-aerosols from an air environment using TiO2 as well as the photocatalytic deodorizing efficacy of a TiO2-type deodorizer; the other study evaluated the changes in perception of a given aroma while inhaling the fragrance of essential oils. In the latter study, we employed a sensory test for evaluating changes in perception of a given aroma. Sensory tests were conducted twice, when participants were undergoing the Kraepelin mental performance test (mental arithmetic or an auditory task (listening to environmental natural sounds, once before the task (pre-task and once after the task (post-task. The perception of fragrance was assessed by 13 contrasting pairs of adjectives as a function of the task assigned to participants. The obtained findings illustrate subtle nuances regarding how essential oils manifest their potency and how olfactory discrimination and responses occur in humans.

  17. Commodification of human tissue: implications for feminist and development ethics.

    Science.gov (United States)

    Dickenson, Donna

    2002-05-01

    One effect of late capitalism--the commodification of practically everything--is to knock down the Chinese walls between the natural and productive realms, to use a Marxist framework. Women's labour in egg extraction and 'surrogate' motherhood might then be seen as what it is, labour which produces something of value. But this does not necessarily mean that women will benefit from the commodification of practically everything, in either North or South. In the newly developing biotechnologies involving stem cells, the reverse is more likely, particular given the the shortage in the North of the egg donors who will be increasingly necessary to therapeutic cloning. Although most of the ethical debate has focused on the status of the embryo, this is to define ethics with no reference to global or gender justice. There has been little or no debate about possible exploitation of women, particularly of ovum donors from the South. Countries of the South without national ethics committees or guidelines may be particularly vulnerable: although there is increasing awareness of the susceptibility of poorer countries to abuses in research ethics, very little has been written about how they might be affected by the enormously profitable new technologies exploiting human tissue. Even in the UK, although the new Medical Research Council guidelines make a good deal of the 'gift relationship', what they are actually about is commodification. If donors believe they are demonstrating altruism, but biotechnology firms and researchers use the discourse of commodity and profit, we have not 'incomplete commodification' but complete commodification with a plausibly human face.

  18. Ethics in action: Approving and improving medical research with human subjects

    NARCIS (Netherlands)

    J.P. de Jong

    2013-01-01

    In this thesis, Jean Philippe de Jong presents a new understanding of ethical oversight on medical research with human subjects and proposes that two philosophies for ethical oversight exist: '(dis)approving' and 'improving'. Systems for ethical oversight on medical research have been in place for m

  19. Model of human visual-motion sensing

    Science.gov (United States)

    Watson, A. B.; Ahumada, A. J., Jr.

    1985-01-01

    A model of how humans sense the velocity of moving images is proposed. The model exploits constraints provided by human psychophysics, notably that motion-sensing elements appear tuned for two-dimensional spatial frequency, and by the frequency spectrum of a moving image, namely, that its support lies in the plane in which the temporal frequency equals the dot product of the spatial frequency and the image velocity. The first stage of the model is a set of spatial-frequency-tuned, direction-selective linear sensors. The temporal frequency of the response of each sensor is shown to encode the component of the image velocity in the sensor direction. At the second stage, these components are resolved in order to measure the velocity of image motion at each of a number of spatial locations and spatial frequencies. The model has been applied to several illustrative examples, including apparent motion, coherent gratings, and natural image sequences. The model agrees qualitatively with human perception.

  20. Ethical issues in neurografting of human embryonic cells.

    Science.gov (United States)

    Boer, G J

    1999-09-01

    During the last decade neurotransplantation has developed into a technique with the possible potential to repair damaged or degenerating human brain. Effective neurotransplantation has so far been based on the use of fetal brain tissue derived from aborted embryos or fetuses. The ethical issues related to this new therapeutic approach therefore not only concern the possible adverse side effects for a neural graft-receiving patient, but also the relationship between the requirements for fetal tissue and the decision-making process for induced abortion. Although for decades human embryos and fetuses have been the subject of biomedical studies, and, in principle, their use has therefore not been seen as ethically objectionable, the above points made it necessary to reconsider the moral issues. The present paper points out several of these issues, both from the donor and acceptor (patient) point of view. The conclusion is that under a series of restrictions intended to prevent the use of grafts from encouraging induced abortions and to maintain high standards of respect for life and human dignity, neurotransplantation using embryonic or fetal brain tissue parts cannot be rejected on moral grounds.

  1. The ethics of human reproductive cloning: when world views collide.

    Science.gov (United States)

    Cohen, Cynthia B

    2004-01-01

    Two camps in bioethics with seemingly opposing world views have staked out conflicting positions regarding the ethics of human reproductive cloning. These camps do not appear to share common concepts or ways of reasoning through which to exchange views and come to a meeting of minds about uses of this technology. Yet analysis of their respective approaches to several issues surrounding reproductive cloning, such as where the ethical limits of individual reproductive choice lie, whether the use of this technology would violate human dignity, whether it would create risks to the resulting fetuses and children that would make its use intolerable, and whether it would challenge certain core social values, reveals that they are not wholly opposed to one another. Indeed, it displays that they hold certain beliefs, values, and concerns in common. Moreover, it indicates that the different world views that they each presuppose, while flawed in certain respects, do not collide in every respect, but can be reconciled in significant ways that provide fertile ground for agreement about several issues related to human reproductive cloning.

  2. Human experimentation: historical perspective of breaches of ethics in US health care.

    Science.gov (United States)

    Layman, Elizabeth J

    2009-01-01

    Health care supervisors and managers may participate in ethical discussions and serve on ethics committees in their health care organizations. To aid them in their participation and service, this article expands upon the knowledge of ethics that they obtained in their academic training. The article provides readers with a common language based on frequently cited cases and key documents. The article traces a brief history of human experimentation, describes ethical breaches in the United States, and summarizes key documents guiding current thought on informed and voluntary consent. The article concludes with 3 common misconceptions that health care supervisors and managers will want to avoid in ethical discussions and ethical decision making. Health care supervisors and managers will be prepared to meaningfully contribute to the discussion of ethical issues and to the resolution of ethical problems in their health care organizations.

  3. Pandemic influenza: human rights, ethics and duty to treat.

    Science.gov (United States)

    Pahlman, I; Tohmo, H; Gylling, H

    2010-01-01

    The 2009 influenza A/H1N1 pandemic seems to be only moderately severe. In the future, a pandemic influenza with high lethality, such as the Spanish influenza in 1918-1919 or even worse, may emerge. In this kind of scenario, lethality rates ranging roughly from 2% to 30% have been proposed. Legal and ethical issues should be discussed before the incident. This article aims to highlight the legal, ethical and professional aspects that might be relevant to anaesthesiologists in the case of a high-lethality infectious disease such as a severe pandemic influenza. The epidemiology, the role of anaesthesiologists and possible threats to the profession and colleagueship within medical specialties relevant to anaesthesiologists are reviewed. During historical plague epidemics, some doctors have behaved like 'deserters'. However, during the Spanish influenza, physicians remained at their jobs, although many perished. In surveys, more than half of the health-care workers have reported their willingness to work in the case of severe pandemics. Physicians have the same human rights as all citizens: they have to be effectively protected against infectious disease. However, they have a duty to treat. Fair and responsible colleagueship among the diverse medical specialties should be promoted. Until disaster threatens humanity, volunteering to work during a pandemic might be the best way to ensure that physicians and other health-care workers stay at their workplace. Broad discussion in society is needed.

  4. [Human dignity as foundation of an ethics in psychiatry].

    Science.gov (United States)

    Achatz, Johannes; Knoepffler, Nikolaus

    2014-07-01

    Psychiatry is distinguished from other fields of medical expertise and bears a particular kind of responsibility, namely the treatment of persons incapable of informed consent per se. The History of psychiatry shows that much too often inhuman abuse was happening in psychiatric facilities. An ethics of psychiatry therefore requires a reliable and stable foundation for values that allow justifying normative claims embracing both characteristics. Such a basic foundation already exists in form of the pluralistic and international recognition of human dignity. We argue that human dignity does and has to go beyond "respect for autonomy" and by that it can function as highest authority on questions concerning value judgments on critical cases in psychiatric bioethics.

  5. Human-animal chimeras: ethical issues about farming chimeric animals bearing human organs.

    Science.gov (United States)

    Bourret, Rodolphe; Martinez, Eric; Vialla, François; Giquel, Chloé; Thonnat-Marin, Aurélie; De Vos, John

    2016-06-29

    Recent advances in stem cells and gene engineering have paved the way for the generation of interspecies chimeras, such as animals bearing an organ from another species. The production of a rat pancreas by a mouse has demonstrated the feasibility of this approach. The next step will be the generation of larger chimeric animals, such as pigs bearing human organs. Because of the dramatic organ shortage for transplantation, the medical needs for such a transgressive practice are indisputable. However, there are serious technical barriers and complex ethical issues that must be discussed and solved before producing human organs in animals. The main ethical issues are the risks of consciousness and of human features in the chimeric animal due to a too high contribution of human cells to the brain, in the first case, or for instance to limbs, in the second. Another critical point concerns the production of human gametes by such chimeric animals. These worst-case scenarios are obviously unacceptable and must be strictly monitored by careful risk assessment, and, if necessary, technically prevented. The public must be associated with this ethical debate. Scientists and physicians have a critical role in explaining the medical needs, the advantages and limits of this potential medical procedure, and the ethical boundaries that must not be trespassed. If these prerequisites are met, acceptance of such a new, borderline medical procedure may prevail, as happened before for in-vitro fertilization or preimplantation genetic diagnosis.

  6. Business Ethics: A Comparison of Business and Humanities Students and Faculty.

    Science.gov (United States)

    Curren, Mary T.; Harich, Katrin R.

    1996-01-01

    The ethics of 17 business scenarios were rated by 115 business students and 35 faculty and 44 humanities students and 22 faculty. Humanities faculty displayed the highest social responsibility, but discipline did not play a significant role overall. Both faculty groups generally had higher personal ethics than did students. (SK)

  7. The value of respect in human research ethics: a conceptual analysis and a practical guide.

    Science.gov (United States)

    Pieper, I J; Thomson, C J H

    2014-01-01

    In order to continue to maintain public trust and confidence in human research, participants must be treated with respect. Researchers and Human Research Ethics Committee members need to be aware that modern considerations of this value include: the need for a valid consenting process, the protection of participants who have their capacity for consent compromised; the promotion of dignity for participants; and the effects that human research may have on cultures and communities. This paper explains the prominence of respect as a value when considering the ethics of human research and provides practical advice for both researchers and Human Research Ethics Committee members in developing respectful research practices.

  8. The survey of clinical human experimentation research in ethical review of postgraduates students.

    Science.gov (United States)

    Xu, Yifan; Zhu, Zheng; Wang, Liyu

    2012-06-01

    An anonymous questionnaire was used to investigate the status quo of ethics review of human subject experiments among postgraduate students in clinical practice with the main conclusions as follows: Human subject experiments make up a large ratio of clinical research; the construction of an ethics review has been initially formulated, but there exists a gap in ethics awareness between advisors and the postgraduates with the desperate need to receive ethics review. It is necessary to realize the importance of informed consent and to strengthen the strict supervision of placebo application.

  9. Toward machines that behave ethically better than humans do

    NARCIS (Netherlands)

    Hoorn, J.F.; Pontier, M.A.

    2012-01-01

    With the increasing dependence on autonomous operating agents and robots the need for ethical machine behavior rises. This paper presents a moral reasoner that combines connectionism, utilitarianism and ethical theory about moral duties. The moral decision-making matches the analysis of expert ethic

  10. Toward machines that behave ethically better than humans do

    NARCIS (Netherlands)

    Hoorn, J.F.; Pontier, M.A.

    2012-01-01

    With the increasing dependence on autonomous operating agents and robots the need for ethical machine behavior rises. This paper presents a moral reasoner that combines connectionism, utilitarianism and ethical theory about moral duties. The moral decision-making matches the analysis of expert ethic

  11. Life in our hands? Some ethical perspectives on the human genome and human genome diversity projects

    Directory of Open Access Journals (Sweden)

    Cornelius W. du Toit

    2014-01-01

    Full Text Available The article dealt with implications of the human genome and the human genome diversity project. It examined some theological implications, such as: humans as the image of God, God as the creator of life, the changed role of miracles and healings in religion, the sacredness of nature, life and the genome. Ethical issues that were addressed include eugenics, germline intervention, determinism and the human genome diversity project. Economic and legal factors that play a role were also discussed. Whilst positive aspects of genome research were considered, a critical stance was adopted towards patenting the human genome and some concluding guidelines were proposed.

  12. Biobanking human embryonic stem cell lines: policy, ethics and efficiency.

    Science.gov (United States)

    Holm, Søren

    2015-12-01

    Stem cell banks curating and distributing human embryonic stem cells have been established in a number of countries and by a number of private institutions. This paper identifies and critically discusses a number of arguments that are used to justify the importance of such banks in policy discussions relating to their establishment or maintenance. It is argued (1) that 'ethical arguments' are often more important in the establishment phase and 'efficiency arguments' more important in the maintenance phase, and (2) that arguments relating to the interests of embryo and gamete donors are curiously absent from the particular stem cell banking policy discourse. This to some extent artificially isolates this discourse from the broader discussions about the flows of reproductive materials and tissues in modern society, and such isolation may lead to the interests of important actors being ignored in the policy making process.

  13. Evaluation in health promotion: thoughts from inside a human research ethics committee.

    Science.gov (United States)

    Allen, Judy; Flack, Felicity

    2015-12-01

    Health promotion research, quality improvement and evaluation are all activities that raise ethical issues. In this paper, the Chair and a member of human resear ch ethics committees provide an insiders' point of view on how to demonstrate ethical conduct in health promotion research and quality improvement. Several common issues raised by health promotion research and evaluation are discussed including researcher integrity, conflicts of interest, use of information, consent and privacy.

  14. Ethical review of research on human subjects at Unilever: reflections on governance.

    Science.gov (United States)

    Sheehan, Mark; Marti, Vernon; Roberts, Tony

    2014-07-01

    This article considers the process of ethical review of research on human subjects at a very large multinational consumer products company. The commercial context of this research throws up unique challenges and opportunities that make the ethics of the process of oversight distinct from mainstream medical research. Reflection on the justification of governance processes sheds important, contrasting light on the ethics of governance of other forms and context of research. © 2013 John Wiley & Sons Ltd.

  15. A critical intersection: human rights, public health nursing, and nursing ethics.

    Science.gov (United States)

    Easley, Cheryl E; Allen, Carol Easley

    2007-01-01

    Public health nurses must make moral decisions regarding practice in complex situations fraught with competing moral claims. While nurses often frame practice decisions within the context of ethical theory, consideration of human rights perspectives is more recent. Basic concepts of nursing and public health ethics and of human rights, in relationship to public health, will be discussed and related to the practice of public health nursing. Intersections of human rights, ethics, and public health nursing practice will be discussed in light of the assertion of health as a human right and described using the issues of HIV/AIDS and genetics/genomics.

  16. The ethics of impossible and possible changes to human nature.

    Science.gov (United States)

    Murphy, Timothy F

    2012-05-01

    Some commentators speak freely about genetics being poised to change human nature. Contrary to such rhetoric, Norman Daniels believes no such thing is plausible since 'nature' describes characteristic traits of human beings as a whole. Genetic interventions that do their work one individual at a time are unlikely to change the traits of human beings as a class. Even so, one can speculate about ways in which human beings as a whole could be genetically altered, and there is nothing about that venture that could not be deliberated in the way other high-impact questions can be evaluated. There might well come a time when it would be defensible to use genetics to change human beings as a class, in order to protect people in the face of changed environmental circumstances or to enhance existing capacities. Moreover, if one understands human nature not in an empirically descriptive way but in a metaphysical way having implications about human behavior, it can make sense to talk about de-naturing individuals through genetic changes. Even under a metaphysical conception of human nature, however, one can still imagine that people in the future might want to alter their traits in pursuit of another normative idea of a good and valuable life, and genetic modifications might function as a pathway to that change.

  17. Ethics of animal research in human disease remediation, its institutional teaching; and alternatives to animal experimentation.

    Science.gov (United States)

    Cheluvappa, Rajkumar; Scowen, Paul; Eri, Rajaraman

    2017-08-01

    Animals have been used in research and teaching for a long time. However, clear ethical guidelines and pertinent legislation were instated only in the past few decades, even in developed countries with Judeo-Christian ethical roots. We compactly cover the basics of animal research ethics, ethical reviewing and compliance guidelines for animal experimentation across the developed world, "our" fundamentals of institutional animal research ethics teaching, and emerging alternatives to animal research. This treatise was meticulously constructed for scientists interested/involved in animal research. Herein, we discuss key animal ethics principles - Replacement/Reduction/Refinement. Despite similar undergirding principles across developed countries, ethical reviewing and compliance guidelines for animal experimentation vary. The chronology and evolution of mandatory institutional ethical reviewing of animal experimentation (in its pioneering nations) are summarised. This is followed by a concise rendition of the fundamentals of teaching animal research ethics in institutions. With the advent of newer methodologies in human cell-culturing, novel/emerging methods aim to minimise, if not avoid the usage of animals in experimentation. Relevant to this, we discuss key extant/emerging alternatives to animal use in research; including organs on chips, human-derived three-dimensional tissue models, human blood derivates, microdosing, and computer modelling of various hues. © 2017 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

  18. Reporting of ethical protection in recent oral and maxillofacial surgery research involving human subjects.

    Science.gov (United States)

    Pitak-Arnnop, P; Sader, R; Hervé, C; Dhanuthai, K; Bertrand, J-Ch; Hemprich, A

    2009-07-01

    This retrospective observational study investigated the frequency of reporting ethical approval and informed consent in recently published oral and maxillofacial surgery (OMS) research involving human subjects. All research involving human subjects published in the International Journal of Oral and Maxillofacial Surgery, Journal of Oral and Maxillofacial Surgery, British Journal of Oral and Maxillofacial Surgery, and Journal of Cranio-Maxillofacial Surgery during January to June 2005-2007 were analysed for disclosure of ethical approval by a local ethical committee and obtaining informed consent from the subjects. 534 articles were identified; ethical approval was documented in 118 (22%) and individual patient consent in 135 (25%). 355 reports (67%) did not include a statement on ethical approval or informed consent and only 74 reports (14%) disclosed statements of both. Ethical documentation in retrospective and observational studies was scant; 12% of randomised controlled trials and 38% of non-random trials did not report both of ethical protections. Most recent OMS publications involving humans failed to mention ethical review or subjects' consent. Authors must adhere to the international research ethics guidelines and journal instructions, while editors should play a gatekeeper role to protect research participants, uphold scientific integrity and maintain public trust in the experimental process and OMS profession.

  19. [Medical, ethical and legal issues in cryopreservation of human embryos].

    Science.gov (United States)

    Beca, Juan Pablo; Lecaros, Alberto; González, Patricio; Sanhueza, Pablo; Mandakovic, Borislava

    2014-07-01

    Embryo cryopreservation improves efficiency and security of assisted reproduction techniques. Nonetheless, it can be questionable, so it must be justified from technical, legal and ethical points of view. This article analyses these perspectives. Embryo cryopreservation maximizes the probability of pregnancy, avoids new ovary stimulations and reduces the occurrence of multiple gestations. There is consensus that the in vitro embryo deserves legal protection by its own, although not as a newborn. Very few countries prohibit embryo cryopreservation based on the legal duty to protect human life since fecundation. Those countries that allow it, privilege women's reproductive rights. In Chile and in Latin America, no laws have been promulgated to regulate human assisted reproduction. The moral status of the embryo depends on how it is considered. Some believe it is a potential person while others think it is just a group of cells, but all recognize that it requires some kind of respect and protection. There is lack of information about the number of frozen embryos and their final destination. As a conclusion the authors propose that women or couples should have the right to decide autonomously, while institutions ought to be clear in their regulations. And the legislation must establish the legal status of the embryo before its implantation, the couples' rights and the regulation of the embryo cryopreservation. Personal, institutional or legal decisions must assume a concept about the moral status of the human embryo and try to avoid their destruction or indefinite storage.

  20. [The beginning of human life: ethical and legal perspectives in the context of biotechnological progress].

    Science.gov (United States)

    Barretto, Vicente de Paulo; Lauxen, Elis Cristina Uhry

    2017-07-13

    Questions concerning the beginning of human life have pervaded society since antiquity. In the post-modern world, scientific and technological advances have fueled discussions on the issue, such that debates previously concentrated on abortion now also focus on biotechnological interventions. The article addresses the latter, reflecting on the extent to which human dignity can be considered a (hermeneutic) reference in establishing ethical and legal parameters for biotechnological advances in the definition of the beginning of human life. The study's method was critical hermeneutic ethics, with ethics at the center of the process of understanding and interpretation, observing the contours of facticity. No consensus was found on the beginning of human life, so it is essential to engage in dialogue with the new reality resulting from biotechnological advances in the process of defining ethical and legal principles for protecting the embryo and human nature, with human dignity as the reference.

  1. Ethical leadership, employee well-being, and helping: the moderating role of human resource management

    NARCIS (Netherlands)

    Kalshoven, K.; Boon, C.T.

    2012-01-01

    In this multi-source study, we examined the link between ethical leadership, human resource management (HRM), employee well-being, and helping. Based on the Conservation of Resources Theory, we proposed a mediated moderation model linking ethical leadership to helping, which includes well-being as

  2. Ethics and human rights issues in perioperative nurses: a subsample of Maryland nurses.

    Science.gov (United States)

    Killen, A R; Fry, S T; Damrosch, S

    1996-04-01

    The purpose of this study was to identify the ethics and human rights issues encountered by Maryland perioperative nurses in their practice. The most frequently occurring issues, the most disturbing issues, and content for ethics education are identified. Implications for education, management, and future research are presented.

  3. Ethical leadership, employee well-being, and helping: the moderating role of human resource management

    NARCIS (Netherlands)

    Kalshoven, K.; Boon, C.T.

    2012-01-01

    In this multi-source study, we examined the link between ethical leadership, human resource management (HRM), employee well-being, and helping. Based on the Conservation of Resources Theory, we proposed a mediated moderation model linking ethical leadership to helping, which includes well-being as a

  4. Creating a Controlled Vocabulary for the Ethics of Human Research: Towards a Biomedical Ethics Ontology

    OpenAIRE

    Koepsell, David; Arp, Robert; Fostel, Jennifer; Smith, Barry

    2009-01-01

    Ontologies describe reality in specific domains in ways that can bridge various disciplines and languages. They allow easier access and integration of information that is collected by different groups. Ontologies are currently used in the biomedical sciences, geography, and law. A Biomedical Ethics Ontology (BMEO) would benefit members of ethics committees who deal with protocols and consent forms spanning numerous fields of inquiry. There already exists the Ontology for Biomedical Investigat...

  5. Chimeras: an ethical consideration

    Directory of Open Access Journals (Sweden)

    H. J.G. Zandman

    2011-07-01

    Full Text Available Scientists have started with experimentation that raises difficult ethical questions. It comprises taking material from the human blueprint (DNA and inserting this in various test animals. The purpose of such research is noble, namely the alleviation of hu- man suffering. Yet the ethical ramifications of blending the hu- man and animal genome are significant, especially for Chris- tians. The creation of all living entities after their kind and the image-bearing dignity attributed to man both come under se- vere ethical stress for those who presuppose divine order in God’s ecology.  For non-Christians the philosophical dilemma ought not to exist in the ethical sense if applied at the purest level. If the human is merely a kind of animal, along with and ontologically not diffe- rent from other animals, there is little logical reason to object to chimeric research apart from a concern about what such re- search and application might do to the order of life pragmati- cally. However, many non-Christian do object. Man is made in God’s image and the concept of human dignity and a universal sense of right and wrong still binds Christians and non-Chris- tians when considering ethics in the field of chimeric research. As the mixing of human stem cells with embryonic animals takes place, certain non-Christian authors protest that human dignity is being diminished and the animal essence is being vio- lated.

  6. Chimeras: an ethical consideration

    Directory of Open Access Journals (Sweden)

    H.J.G. Zandman

    2011-07-01

    Full Text Available Scientists have started with experimentation that raises difficult ethical questions. It comprises taking material from the human blueprint (DNA and inserting this in various test animals. The purpose of such research is noble, namely the alleviation of hu- man suffering. Yet the ethical ramifications of blending the hu- man and animal genome are significant, especially for Chris- tians. The creation of all living entities after their kind and the image-bearing dignity attributed to man both come under se- vere ethical stress for those who presuppose divine order in God’s ecology.  For non-Christians the philosophical dilemma ought not to exist in the ethical sense if applied at the purest level. If the human is merely a kind of animal, along with and ontologically not diffe- rent from other animals, there is little logical reason to object to chimeric research apart from a concern about what such re- search and application might do to the order of life pragmati- cally. However, many non-Christian do object. Man is made in God’s image and the concept of human dignity and a universal sense of right and wrong still binds Christians and non-Chris- tians when considering ethics in the field of chimeric research. As the mixing of human stem cells with embryonic animals takes place, certain non-Christian authors protest that human dignity is being diminished and the animal essence is being vio- lated.

  7. Toward machines that behave ethically better than humans do

    NARCIS (Netherlands)

    Hoorn, J.F.; Pontier, M.A.

    2012-01-01

    With the increasing dependence on autonomous operating agents and robots the need for ethical machine behavior rises. This paper presents a moral reasoner that combines connectionism, utilitarianism and ethical theory about moral duties. The moral decision-making matches the analysis of expert

  8. [Ethics, medical ethics, and occupational medicine: is their dialogue possible?].

    Science.gov (United States)

    Buzzi, Elisa

    2016-01-20

    Today's medicine faces some critical moral challenges, yet the medical class suffers from an increasingly evident malaise: a growing dissatisfaction with an ethical demand often perceived as a cumbersome burden of rules and prohibitions, which risk to erode the fiduciary relations with patients. Such a negative appraisal is partly due to a narrow interpretation of the meaning of ethics, a misconception whose roots are in the positivistic stance that permeates our culture, and in its almost exclusively technological bent. This radical orientation of our culture shows itself in the vanishing of the idea of an intrinsic ethical dimension of medicine and consequent eclipse of traditional medical ethics, currently all but assimilated by bioethics. Maintaining a clear distinction between medical ethics and bioethics is a fundamental condition for guaranteeing an original ethical reflection in medicine, thereby fostering a constructive dialogue between philosophical and medical ethics. In this sense, occupational medicine holds a very propitious position, at the cross-roads to some of the most important dimensions in human life and society: health, work, environment. In a milieu which is too often inclined to efface the living human being and the deepest needs of humanity, the moral commitment of medical profession to the care of the integral reality of the embodied human person is one of the most important ethical challenges facing occupational medicine and a most valuable contribution to the current ethical debate.

  9. e-Government Ethics : a Synergy of Computer Ethics, Information Ethics, and Cyber Ethics

    Directory of Open Access Journals (Sweden)

    Arief Ramadhan

    2011-08-01

    Full Text Available Ethics has become an important part in the interaction among humans being. This paper specifically discusses applied ethics as one type of ethics. There are three applied ethics that will be reviewed in this paper, i.e. computer ethics, information ethics, and cyber ethics. There are two aspects of the three applied ethics that were reviewed, i.e. their definition and the issues associated with them. The reviewing results of the three applied ethics are then used for defining e-Government ethics and formulating the issues of e-Government ethics. The e-Government ethics position, based on the previous three applied ethics, is also described in this paper. Computer ethics, information ethics and cyber ethics are considered as the foundations of e-Government ethics and several others applied ethics could enrich the e-Government ethics.

  10. Contemporary ethical issues in human milk-banking in the United States.

    Science.gov (United States)

    Miracle, Donna J; Szucs, Kinga A; Torke, Alexia M; Helft, Paul R

    2011-12-01

    Donor human milk has been used in the United States for >90 years, but recent advances in human milk science and laboratory techniques have led to increasing use of this resource. Pediatricians began using donor human milk in the 1900s in response to anecdotal observation that premature infants had better health outcomes when receiving their own mothers' milk. Since then, a formalized human milk-banking system developed in the mid-1980s and distributed >1 million ounces of pasteurized donor human milk in 2008. Despite growth in the use of pasteurized donor human milk, there is little discussion in the medical literature regarding the ethical considerations of collection and use of this resource. Key ethical considerations include issues surrounding medical decision-making and informed consent, increasing the limited supply of human milk, how ethically to allocate this scarce resource, and concerns linked to the marketing of a human milk.

  11. The influence of human resource management on improvement of business ethics

    Directory of Open Access Journals (Sweden)

    Radenko Maric

    2010-02-01

    Full Text Available In this paper the importance of practice of human resource management as of a significant driver of business ethics in companies has been considered. The basic premise of the paper is the fact that the company’s main source of unethical behaviour is situated in its people’s activities which further implies that many measures aimed to apply and improve business ethics belong to the domain of human resource management. Based on research results on a sample of 36 enterprises, the paper attempts to answer important questions as: what are the problems regarding business ethics facing human resource experts and to what extent the existing human resource management practices influence the application and improvement of business ethics in Serbian enterprises.

  12. Hans Jonas' Thought on The Ethics of Research on Human Subjects

    African Journals Online (AJOL)

    Dr Olaleye

    Subjects: Implications for Contemporary Medical Research in. Nigeria. Ebeh J.I1 and ... Keywords: Human Research ethics, Nigeria, Hans Jonas. *Author for corresp .... 1998) reported a case of over sixty embryos that were transplanted into ...

  13. Evolution of Attitudes in the Field of Human Research Ethics

    Directory of Open Access Journals (Sweden)

    Hugo Escobar-Melo

    2008-05-01

    Full Text Available The state of evolution of attitudes in a sample of 142 Medical Students at the Pontificia Universidad Javeriana in Bogota (at the beginning, middle and ending of their studies in the field of Human Research Ethics (HRE is analytically described. A complex scale of attitudes was used, with three components: affective, beliefs-related and behavioral, further divided into three theoretical categories taken from Bioethics: Subject-End/means- Dignity, Benefit and Justice. The relationship between the current medical education process and the attitudes regarding HRE in the sample are analyzed.A small trend towards progress in all categories and in all components of attitudes throughout medical education is described; neither the Benefit nor the Subject-End/means/Dignity categories evolve in a significant way; some significant differences were observed in the Justice category (beliefs and behavioral and in the Subject-End/means-Dignity category (beliefs component. The results allow for asking about the role of formation and evolution of those attitudes throughout the academic process. In conclusion, attitudes seem to be progressing relatively, without a decisive evolution.

  14. A code of ethics for evidence-based research with ancient human remains.

    Science.gov (United States)

    Kreissl Lonfat, Bettina M; Kaufmann, Ina Maria; Rühli, Frank

    2015-06-01

    As clinical research constantly advances and the concept of evolution becomes a strong and influential part of basic medical research, the absence of a discourse that deals with the use of ancient human remains in evidence-based research is becoming unbearable. While topics such as exhibition and excavation of human remains are established ethical fields of discourse, when faced with instrumentalization of ancient human remains for research (i.e., ancient DNA extractions for disease marker analyses) the answers from traditional ethics or even more practical fields of bio-ethics or more specific biomedical ethics are rare to non-existent. The Centre for Evolutionary Medicine at the University of Zurich solved their needs for discursive action through the writing of a self-given code of ethics which was written in dialogue with the researchers at the Institute and was published online in Sept. 2011: http://evolutionäremedizin.ch/coe/. The philosophico-ethical basis for this a code of conduct and ethics and the methods are published in this article. © 2015 Wiley Periodicals, Inc.

  15. Unfinished business: ongoing ethical exceptionalism in the oversight of human pluripotent stem cell research in Canada.

    Science.gov (United States)

    Baylis, Françoise; Downie, Jocelyn

    2012-01-01

    In this article, we critically examine the arguments for and against the exceptional status given human pluripotent stem cell research in Canada (through the latest [December 2010] revision of the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans), and conclude that this exceptionalism is unwarranted and ethically unsound. In our view, the three federal research granting agencies should honor their longstanding commitment that researchers, research sponsors, and Research Ethics Boards in Canada have access to "a single reference document for all research involving humans conducted under the auspices of institutions eligible for Agency funding." As well, responsibility for the development, interpretation, and implementation of Canada's research ethics guidelines should be under the authority of a single oversight body that is independent of the federal research granting Agencies.

  16. Human embryonic stem cell research: implications from an ethical and legal standpoint.

    Science.gov (United States)

    Trepagnier, D M

    2000-12-01

    The purpose of this paper is to discuss the ethical and legal implications of one of the newest and most controversial medical breakthroughs. Stem cell research has been performed on mice for many years, but human embryonic stem cells are believed by scientists to be the basis for possible treatments and/or cures to many diseases affecting millions of people around the world. In order to perform research on human embryonic stem cells, numerous ethical issues must be addressed. Guidelines and protocols can be established in order to allow scientists to pursue new medical advances while maintaining the highest ethical standards in the use of human embryos. An alternative to using embryos is adult stem cells which have recently proven to be more versatile than previously believed. Opposing views will always be encountered when facing new science technologies. Where should the ethical line be drawn?

  17. Psychotherapy is an ethical endeavor: Balancing science and humanism in clinical practice.

    Science.gov (United States)

    Allen, Jon G

    2013-01-01

    The author proposes that psychotherapy is best grounded in scienceinformed humanism and, more specifically, that psychotherapists at least implicitly promote ethical, moral--and indeed, virtuous--behavior. In doing so, therapists are challenged continually to engage in making evaluative moral judgments without being judgmental. He contends that psychotherapists, and psychologists especially, are overly reliant on science and might benefit from being more explicit in their ethical endeavors by being better informed about the illuminating philosophical literature on ethics. He highlights the concept of mentalizing, that is, attentiveness to mental states in self and others, such as needs, feelings, and thoughts. He proposes that mentalizing in the context of attachment relationships is common to all psychotherapies, and that this common process is best understood conjointly from the perspectives of developmental psychology and ethics. The author defends the thesis that employing psychotherapy to promote ethical, moral, and virtuous functioning can be justified on scientific grounds insofar as this functioning is conducive to health.

  18. Ethical issues in human reproduction: Protestant perspectives in the light of European Protestant and Reformed Churches.

    Science.gov (United States)

    Birkhäuser, Martin

    2013-11-01

    Protestantism is not a centralized religion. It is composed by many independent Churches having different moral and ethical standards. This review concentrates on the ethical principles prevalent in most modern European Reformed Churches. It does not intend to discuss the ethical principles of many other Protestant Churches present mainly in the USA. The common foundations of Protestant theology are the "five sola ("Sola scriptura", Sola fide", "Sola gratia", Solus Christus or Solo Christo", "Soli deo gloria"). In opposition to the Catholic Church, no intermediary is needed between the Bible and the believer. As a consequence, Protestant Churches have no Magisterium, such as the Catholic Church. Therefore Protestant Churches cannot declare a certain position to be the "official position". Each Christian is personally responsible for all his acts, including his ethical behaviour. There is no complete unanimity among all Protestants on ethics or on any other issue. Human dignity, personal rights and self-determination have to be respected in each ethical consideration. The supersession of the Old Mosaic Covenant (including traditional Jewish law or Halakhah, maintained in Catholicism) by the New Covenant and by Christian Theology has an important impact on Protestant ethics in reproductive medicine. In the New Covenant, the Protestants Churches did not maintain the mandatory obligation from the old Mosaic Covenant to be fruitful and to multiply: there is no divine obligation by God to procreate. As a consequence, contraception is not a sin and not unethical. The status of the embryo is the key for the ethical consideration of all methods used in reproductive medicine. Most representatives of modern Protestant theology and bioethics defend the opinion that the embryo is not an independent human being as is the newborn child. For most Protestant bio-ethicists, as long as an embryo has no nervous system, no organs and no pain receptors, it cannot be seen as a human

  19. The challenge of promoting professionalism through medical ethics and humanities education.

    Science.gov (United States)

    Doukas, David J; McCullough, Laurence B; Wear, Stephen; Lehmann, Lisa S; Nixon, Lois LaCivita; Carrese, Joseph A; Shapiro, Johanna F; Green, Michael J; Kirch, Darrell G

    2013-11-01

    Given recent emphasis on professionalism training in medical schools by accrediting organizations, medical ethics and humanities educators need to develop a comprehensive understanding of this emphasis. To achieve this, the Project to Rebalance and Integrate Medical Education (PRIME) II Workshop (May 2011) enlisted representatives of the three major accreditation organizations to join with a national expert panel of medical educators in ethics, history, literature, and the visual arts. PRIME II faculty engaged in a dialogue on the future of professionalism in medical education. The authors present three overarching themes that resulted from the PRIME II discussions: transformation, question everything, and unity of vision and purpose.The first theme highlights that education toward professionalism requires transformational change, whereby medical ethics and humanities educators would make explicit the centrality of professionalism to the formation of physicians. The second theme emphasizes that the flourishing of professionalism must be based on first addressing the dysfunctional aspects of the current system of health care delivery and financing that undermine the goals of medical education. The third theme focuses on how ethics and humanities educators must have unity of vision and purpose in order to collaborate and identify how their disciplines advance professionalism. These themes should help shape discussions of the future of medical ethics and humanities teaching.The authors argue that improvement of the ethics and humanities-based knowledge, skills, and conduct that fosters professionalism should enhance patient care and be evaluated for its distinctive contributions to educational processes aimed at producing this outcome.

  20. Ethical Standards of Scientific Research Involving Human Subjects in Brazil: Perspectives Concerning Psychology

    Directory of Open Access Journals (Sweden)

    Selma Leitão

    2015-01-01

    Full Text Available AbstractBrazilian associations for research in human, social and applied social sciences have long sought ethical aspects regulation compatible with the epistemological, theoretical and methodological specificities of these sciences. Consequently, the Brazilian regulatory system (Research Ethics Committees/CEPs of the National Research Ethics Commission/CONEP is currently undergoing an important review process. This article presents the positions taken by the National Association of Research and Postgraduate Studies in Psychology - ANPEPP. The article: (1 highlights the origins of the current ethics review model, based on biomedical research; (2 summarizes criticisms recurrent to this model; (3 identifies the directions required for the improvement of the system; and (4 lists the challenges to be overcome in the current process of creating specific regulations for the human and social sciences. The considerations presented highlight two crucial points that challenge the construction of a specific resolution for research ethics in the human and social sciences: (1 the clear characterization of what is meant by 'research in the human and social sciences' - and that would, therefore, have its ethical review regulated from the perspective of the specific resolution for the human and social sciences; and (2 the definition of parameters from which different risk levels in studies can be identified.

  1. Transforming educational accountability in medical ethics and humanities education toward professionalism.

    Science.gov (United States)

    Doukas, David J; Kirch, Darrell G; Brigham, Timothy P; Barzansky, Barbara M; Wear, Stephen; Carrese, Joseph A; Fins, Joseph J; Lederer, Susan E

    2015-06-01

    Effectively developing professionalism requires a programmatic view on how medical ethics and humanities should be incorporated into an educational continuum that begins in premedical studies, stretches across medical school and residency, and is sustained throughout one's practice. The Project to Rebalance and Integrate Medical Education National Conference on Medical Ethics and Humanities in Medical Education (May 2012) invited representatives from the three major medical education and accreditation organizations to engage with an expert panel of nationally known medical educators in ethics, history, literature, and the visual arts. This article, based on the views of these representatives and their respondents, offers a future-tense account of how professionalism can be incorporated into medical education.The themes that are emphasized herein include the need to respond to four issues. The first theme highlights how ethics and humanities can provide a response to the dissonance that occurs in current health care delivery. The second theme focuses on how to facilitate preprofessional readiness for applicants through reform of the medical school admission process. The third theme emphasizes the importance of integrating ethics and humanities into the medical school administrative structure. The fourth theme underscores how outcomes-based assessment should reflect developmental milestones for professional attributes and conduct. The participants emphasized that ethics and humanities-based knowledge, skills, and conduct that promote professionalism should be taught with accountability, flexibility, and the premise that all these traits are essential to the formation of a modern professional physician.

  2. Ethics education in research involving human beings in undergraduate medicine curriculum in Brazil.

    Science.gov (United States)

    Novaes, Maria Rita Garbi; Guilhem, Dirce; Barragan, Elena; Mennin, Stewart

    2013-12-01

    The Brazilian national curriculum guidelines for undergraduate medicine courses inspired and influenced the groundwork for knowledge acquisition, skills development and the perception of ethical values in the context of professional conduct. The evaluation of ethics education in research involving human beings in undergraduate medicine curriculum in Brazil, both in courses with active learning processes and in those with traditional lecture learning methodologies. Curricula and teaching projects of 175 Brazilian medical schools were analyzed using a retrospective historical and descriptive exploratory cohort study. Thirty one medical schools were excluded from the study because of incomplete information or a refusal to participate. Active research for information from institutional sites and documents was guided by terms based on 69 DeCS/MeSH descriptors. Curriculum information was correlated with educational models of learning such as active learning methodologies, tutorial discussions with integrated curriculum into core modules, and traditional lecture learning methodologies for large classes organized by disciplines and reviewed by occurrence frequency of ethical themes and average hourly load per semester. Ninety-five medical schools used traditional learning methodologies. The ten most frequent ethical themes were: 1--ethics in research (26); 2--ethical procedures and advanced technology (46); 3--ethic-professional conduct (413). Over 80% of schools using active learning methodologies had between 50 and 100 hours of scheduled curriculum time devoted to ethical themes whereas more than 60% of traditional learning methodology schools devoted less than 50 hours in curriculum time to ethical themes. The data indicates that medical schools that employ more active learning methodologies provide more attention and time to ethical themes than schools with traditional discipline-based methodologies. Given the importance of ethical issues in contemporary medical

  3. Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?

    Science.gov (United States)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2015-12-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.

  4. Introducing Human Rights Education in the Confucian Society of Taiwan: Its Implications for Ethical Leadership in Education.

    Science.gov (United States)

    Hwang, Kwang-Kuo

    2001-01-01

    Discusses recent introduction of human-rights education in Taiwan. Describes essential characteristics of Confucian ethics; compares Confucianism with ethical leadership in education. Discusses relationship between findings on the use of corporal punishment in Taiwanese schools and ethical leadership. Describes worldwide use of corporal punishment…

  5. Introducing Human Rights Education in the Confucian Society of Taiwan: Its Implications for Ethical Leadership in Education.

    Science.gov (United States)

    Hwang, Kwang-Kuo

    2001-01-01

    Discusses recent introduction of human-rights education in Taiwan. Describes essential characteristics of Confucian ethics; compares Confucianism with ethical leadership in education. Discusses relationship between findings on the use of corporal punishment in Taiwanese schools and ethical leadership. Describes worldwide use of corporal punishment…

  6. Robotic Nudges: The Ethics of Engineering a More Socially Just Human Being.

    Science.gov (United States)

    Borenstein, Jason; Arkin, Ron

    2016-02-01

    Robots are becoming an increasingly pervasive feature of our personal lives. As a result, there is growing importance placed on examining what constitutes appropriate behavior when they interact with human beings. In this paper, we discuss whether companion robots should be permitted to "nudge" their human users in the direction of being "more ethical". More specifically, we use Rawlsian principles of justice to illustrate how robots might nurture "socially just" tendencies in their human counterparts. Designing technological artifacts in such a way to influence human behavior is already well-established but merely because the practice is commonplace does not necessarily resolve the ethical issues associated with its implementation.

  7. Engaging research participants to inform the ethical conduct of mobile imaging, pervasive sensing, and location tracking research.

    Science.gov (United States)

    Nebeker, Camille; Lagare, Tiffany; Takemoto, Michelle; Lewars, Brittany; Crist, Katie; Bloss, Cinnamon S; Kerr, Jacqueline

    2016-12-01

    Researchers utilize mobile imaging, pervasive sensing, social media, and location tracking (MISST) technologies to observe and intervene with participants in their natural environment. The use of MISST methods and tools introduces unique ethical issues due to the type and quantity of data, and produces raising new challenges around informed consent, risk assessment, and data management. Since MISST methods are relatively new in behavioral research, there is little documented evidence to guide institutional review board (IRB) risk assessment and inform appropriate risk management strategies. This study was conducted to contribute the participant perspectives when considering ethical and responsible practices. Participants (n = 82) enrolled in an observational study where they wore several MISST devices for 1 week completed an exit survey. Survey items focused on the following: 1-device comfort, 2-informed consent, 3-privacy protections, and 4-bystander engagement. The informed consent process reflected participant actual experience. Device comfort and privacy were raised as concerns to both the participants and bystanders. While the majority of the participants reported a positive experience, it is important to note that the participants were volunteers who were not mandated to wear tracking devices and that persons who are mandated may not have a similar response. Findings support strategies proposed in the Kelly et al. (2013) ethical framework, which emphasizes procedures to improve informed consent, protect privacy, manage data, and respect bystander rights when using a wearable camera.

  8. Heterogeneity of Human Research Ethics Committees and Research Governance Offices across Australia: An observational study.

    Science.gov (United States)

    De Smit, Elisabeth; Kearns, Lisa S; Clarke, Linda; Dick, Jonathan; Hill, Catherine L; Hewitt, Alex W

    2016-01-01

    Conducting ethically grounded research is a fundamental facet of all investigations. Nevertheless, the administrative burdens of current ethics review are substantial, and calls have been made for a reduction in research waste. To describe the heterogeneity in administration and documentation required by Human Research Ethics Committees (HRECs) and Research Governance Offices (RGOs) across Australia. In establishing a nationwide study to investigate the molecular aetiology of Giant Cell Arteritis (GCA), for which archived pathological specimens from around Australia are being recruited, we identified variation across separate HREC and RGO requirements. Submission paperwork and correspondence from each collaborating site and its representative office for research were reviewed. This data was interrogated to evaluate differences in current guidelines. Twenty-five pathology departments across seven Australian States collaborated in this study. All states, except Victoria, employed a single ethics review model. There was discrepancy amongst HRECs as to which application process applied to our study: seven requested completion of a "National Ethics Application Form" and three a "Low Negligible Risk" form. Noticeable differences in guidelines included whether electronic submission was sufficient. There was variability in the total number of documents submitted (range five to 22) and panel review turnaround time (range nine to 136 days). We demonstrate the challenges and illustrate the heavy workload involved in receiving widespread ethics and governance approval across Australia. We highlight the need to simplify, homogenise, and nationalise human ethics for non-clinical trial studies. Reducing unnecessary administration will enable investigators to achieve research aims more efficiently.

  9. Can artificial parthenogenesis sidestep ethical pitfalls in human therapeutic cloning? An historical perspective

    Science.gov (United States)

    Fangerau, H

    2005-01-01

    The aim of regenerative medicine is to reconstruct tissue that has been lost or pathologically altered. Therapeutic cloning seems to offer a method of achieving this aim; however, the ethical debate surrounding human therapeutic cloning is highly controversial. Artificial parthenogenesis—obtaining embryos from unfertilised eggs—seems to offer a way to sidestep these ethical pitfalls. Jacques Loeb (1859–1924), the founding father of artificial parthogenesis, faced negative public opinion when he published his research in 1899. His research, the public's response to his findings, and his ethical foundations serve as an historical argument both for the communication of science and compromise in biological research. PMID:16319240

  10. A study on the effects of productivity of human resources in banking network and work ethics

    Directory of Open Access Journals (Sweden)

    Zahra Vazifeh

    2014-07-01

    Full Text Available Today, human resources are considered as the most important assets of any organization. Generally, human being has specific ethical features on personality characteristics forming the attitude, speech and behavior. It is possible that some factors create different attitudes, speech and behavior among people who are in one particular position. These human characteristics influence the efficiency and effectiveness of organization. The present study aims to investigate the relationship between work ethics and human resources productivity in banking network of city of Zahedan, Iran. The study chooses a sample of 236 employees who worked for different banks in city of Zahedan, Iran in 2013. To analyze the data, Pearson correlation test, Friedman ranking and independent t-test were used. The results show that there was a significant association between work ethics components and productivity (efficiency and effectiveness of human resources.

  11. Inferring Human Mobility from Sparse Low Accuracy Mobile Sensing Data

    DEFF Research Database (Denmark)

    Cuttone, Andrea; Jørgensen, Sune Lehmann; Larsen, Jakob Eg

    2014-01-01

    Understanding both collective and personal human mobility is a central topic in Computational Social Science. Smartphone sensing data is emerging as a promising source for studying human mobility. However, most literature focuses on high-precision GPS positioning and high-frequency sampling, which...... is not always feasible in a longitudinal study or for everyday applications because location sensing has a high battery cost. In this paper we study the feasibility of inferring human mobility from sparse, low accuracy mobile sensing data. We validate our results using participants' location diaries......, and analyze the inferred geographical networks, the time spent at different places, and the number of unique places over time. Our results suggest that low resolution data allows accurate inference of human mobility patterns....

  12. Persistant Pursuit for Ethics to Promote Human Health%矢志伦理为健康

    Institute of Scientific and Technical Information of China (English)

    李恩昌

    2011-01-01

    This paper gives a brief introduction of the author's personal experience of the 30 years'research on medical humanities, medical ethics, and journal compiling on the journal of Chinese Medical Ethics.%简略回顾了作者从事医学人文科学、医学伦理学研究30年的历程和从事杂志等期刊编辑工作的若干内容.

  13. [Ethical issues of human experimentation with special reference to informed consent].

    Science.gov (United States)

    Saso, L; Silvestrini, B

    2000-10-01

    Human experimentation in order to develop new medical therapies creates very complex ethical problems: when is it possible to test a new therapy on a human subject? Is it always necessary his/her consent? Which information should be given to the subject before requesting his/her consent? How to behave in the case of minors, psychiatric patients and other subjects not perfectly free or able to understand the information provided? Is it right to subject a person to an experimentation from which he/she will not get any direct advantage? Which results can be published? In other words, which are the ethical limits of human experimentation? These are difficult questions, to which the authors tried to answer referring to some ethically significant human experimentations, such as those performed by Lind and Jenner in the XVIII century, and those carried out by the nazi doctors, from whose trial derived the Nuremberg Code, which introduced for the first time, at an international level, the principle of the informed consent. Some of the limits of this document, including the impossibility of doing research on subjects not able to give their informed consent, such as minors and psychiatric patients, were overcome by the Declaration of Helsinki, whose current version resulted from several subsequent revisions. According to this document, a major role is played by the Institutional Review Boards or Institutional Ethical Committees that have the heavy responsibility of evaluating the ethical connotations of human experimentations.

  14. Robot Enhancement of Cognitive and Ethical Capabilities of Humans

    NARCIS (Netherlands)

    Fosch Villaronga, Eduard; Kalipalya-Mruthyunjaya, Vishwas; Seibt, Johanna; Norskov, Marco; Andersen, Soren Schack

    2016-01-01

    The aim of this paper is to mold and materialize the future of learning. The paper introduces a Modular Cognitive Educator System (MCES), which aims to help people learn cognitive and ethical capabilities to face one of the indirect impacts of the robot revolution, namely, its impact on the educatio

  15. Humanity in the Digital Age: Cognitive, Social, Emotional, and Ethical Implications

    Science.gov (United States)

    Yamamoto, Junko; Ananou, Simeon

    2015-01-01

    Even though technology has brought great benefits to current society, there are also indications that the manner in which people use technology has undermined their humanity in some respects. In this article the authors frame human nature in terms of four dimensions: cognition, social interaction, emotion, and ethics. We argue that while basic…

  16. Development ethics through the lenses of caring, gender, and human security.

    NARCIS (Netherlands)

    D.R. Gasper (Des); T-D. Truong (Thanh-Dam)

    2008-01-01

    textabstractThinking about ethics of development and human development must both treat development in a global perspective and yet reflect on the content of human. This paper explores some faces of globalization by using a gender perspective, in order to consider reproduction (psychological and

  17. When Being Virtuous Makes Sense: Bourgeois Ethics in the Golden Age vs. Embarrassment

    NARCIS (Netherlands)

    A. Yalç intas

    2004-01-01

    textabstractHave you ever thought of virtues? Temperance, Courage, Justice, Hope, and Love, just to name a few. And, have you ever thought that they could have anything to do with economics? Economists have long ago separated the moral philosophy (ethics) and the science of choice (economics) from e

  18. Human motion sensing and recognition a fuzzy qualitative approach

    CERN Document Server

    Liu, Honghai; Ji, Xiaofei; Chan, Chee Seng; Khoury, Mehdi

    2017-01-01

    This book introduces readers to the latest exciting advances in human motion sensing and recognition, from the theoretical development of fuzzy approaches to their applications. The topics covered include human motion recognition in 2D and 3D, hand motion analysis with contact sensors, and vision-based view-invariant motion recognition, especially from the perspective of Fuzzy Qualitative techniques. With the rapid development of technologies in microelectronics, computers, networks, and robotics over the last decade, increasing attention has been focused on human motion sensing and recognition in many emerging and active disciplines where human motions need to be automatically tracked, analyzed or understood, such as smart surveillance, intelligent human-computer interaction, robot motion learning, and interactive gaming. Current challenges mainly stem from the dynamic environment, data multi-modality, uncertain sensory information, and real-time issues. These techniques are shown to effectively address the ...

  19. Human Embryonic Stem Cell Research: Ethical Views of Buddhist, Hindu and Catholic Leaders in Malaysia.

    Science.gov (United States)

    Sivaraman, Mathana Amaris Fiona; Noor, Siti Nurani Mohd

    2016-04-01

    Embryonic Stem Cell Research (ESCR) raises ethical issues. In the process of research, embryos may be destroyed and, to some, such an act entails the 'killing of human life'. Past studies have sought the views of scientists and the general public on the ethics of ESCR. This study, however, explores multi-faith ethical viewpoints, in particular, those of Buddhists, Hindus and Catholics in Malaysia, on ESCR. Responses were gathered via semi-structured, face-to-face interviews. Three main ethical quandaries emerged from the data: (1) sanctity of life, (2) do no harm, and (3) 'intention' of the research. Concerns regarding the sanctity of life are directed at particular research protocols which interfere with religious notions of human ensoulment and early consciousness. The principle of 'do no harm' which is closely related to ahimsa prohibits all acts of violence. Responses obtained indicate that respondents either discourage research that inflicts harm on living entities or allow ESCR with reservations. 'Intention' of the research seems to be an interesting and viable rationale that would permit ESCR for the Buddhists and Hindus. Research that is intended for the purpose of alleviating human suffering is seen as being ethical. This study also notes that Catholics oppose ESCR on the basis of the inviolability of human life.

  20. The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas

    Directory of Open Access Journals (Sweden)

    London Leslie

    2010-08-01

    Full Text Available Abstract The controversy about the use of data from human volunteer studies involving experimental exposure to pesticides as part of regulatory risk assessment has been widely discussed, but the complex and interrelated scientific and ethical issues remain largely unresolved. This discussion paper, generated by authors who comprised a workgroup of the ICOH Scientific Committee on Rural Health, reviews the use of human experimental studies in regulatory risk assessment for pesticides with a view to advancing the debate as to when, if ever, such studies might be ethically justifiable. The discussion is based on three elements: (a a review of discussion papers on the topic of human testing of pesticides and the positions adopted by regulatory agencies in developed countries; (b an analysis of published and unpublished studies involving human testing with pesticides, both in the peer-reviewed literature and in the JMPR database; and (c application of an ethical analysis to the problem. The paper identifies areas of agreement which include general principles that may provide a starting point on which to base criteria for judgements as to the ethical acceptability of such studies. However, the paper also highlights ongoing unresolved differences of opinion inherent in ethical analysis of contentious issues, which we propose should form a starting point for further debate and the development of guidelines to achieve better resolution of this matter.

  1. The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas

    Science.gov (United States)

    2010-01-01

    The controversy about the use of data from human volunteer studies involving experimental exposure to pesticides as part of regulatory risk assessment has been widely discussed, but the complex and interrelated scientific and ethical issues remain largely unresolved. This discussion paper, generated by authors who comprised a workgroup of the ICOH Scientific Committee on Rural Health, reviews the use of human experimental studies in regulatory risk assessment for pesticides with a view to advancing the debate as to when, if ever, such studies might be ethically justifiable. The discussion is based on three elements: (a) a review of discussion papers on the topic of human testing of pesticides and the positions adopted by regulatory agencies in developed countries; (b) an analysis of published and unpublished studies involving human testing with pesticides, both in the peer-reviewed literature and in the JMPR database; and (c) application of an ethical analysis to the problem. The paper identifies areas of agreement which include general principles that may provide a starting point on which to base criteria for judgements as to the ethical acceptability of such studies. However, the paper also highlights ongoing unresolved differences of opinion inherent in ethical analysis of contentious issues, which we propose should form a starting point for further debate and the development of guidelines to achieve better resolution of this matter. PMID:20718963

  2. Inertial and magnetic sensing of human motion

    NARCIS (Netherlands)

    Roetenberg, Daniel

    2006-01-01

    Movement and posture tracking of the human body is of great interest in many different disciplines such as monitoring of activities of daily living, assessment of working load in ergonomics studies, measurement of neurological disorders, computer animation, and virtual reality applications. This the

  3. Human Participants in Engineering Research: Notes from a Fledgling Ethics Committee.

    Science.gov (United States)

    Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

    2015-08-01

    For the past half-century, issues relating to the ethical conduct of human research have focused largely on the domain of medical, and more recently social-psychological research. The modern regime of applied ethics, emerging as it has from the Nuremberg trials and certain other historical antecedents, applies the key principles of: autonomy, respect for persons, beneficence, non-maleficence, and justice to human beings who enter trials of experimental drugs and devices (Martensen in J Hist Med Allied Sci 56(2):168-175, 2001). Institutions such as Institutional Review Boards (in the U.S.) and Ethics Committees (in Europe and elsewhere) oversee most governmentally-funded medical research around the world, in more than a hundred nations that are signers of the Declaration of Helsinki (World Medical Association 2008). Increasingly, research outside of medicine has been recognized to pose potential risks to human subjects of experiments. Ethics committees now operate in the US, Canada, the U.K. and Australia to oversee all governmental-funded research, and in other jurisdictions, the range of research covered by such committees is expanding. Social science, anthropology, and other fields are falling under more clear directives to conduct a formal ethical review for basic research involving human participants (Federman et al. in Responsible research: a systems approach to protecting research participants. National Academies Press, Washington, 2003, p. 36). The legal and institutional response for protecting human subjects in the course of developing non-medical technologies, engineering, and design is currently vague, but some universities are establishing ethics committees to oversee their human subjects research even where the experiments involved are non-medical and not technically covered by the Declaration of Helsinki. In The Netherlands, as in most of Europe, Asia, Latin America, or Africa, no laws mandate an ethical review of non-medical research. Yet, nearly 2

  4. Ethical Considerations in Mandatory Disclosure of Data Acquired While Caring for Human Trafficking Survivors.

    Science.gov (United States)

    Kerr, Patrick L; Dash, Rachel

    2017-01-01

    Accurate data on the prevalence and psychological effects of human trafficking as well as treatment outcomes for survivors are essential for measuring the impact of interventions and generating better understanding of this phenomenon. However, such data are difficult to obtain. A legal mandate for health care professionals to report trafficking opens opportunities for advancing our work in the field of human trafficking but also poses risks to survivors seeking services. In this article, we provide an analysis of some critical ethical considerations for the development and implementation of a mandatory reporting policy and offer recommendations for the ethical implementation of such a policy.

  5. A Synergistic Approach to Human Rights and Public Health Ethics: Effective or a Source of Conflict?

    Directory of Open Access Journals (Sweden)

    Steinmetz-Wood, Madeleine

    2014-12-01

    Full Text Available Concerns over the growing disparities in health and wealth between members of society incited Stephanie Nixon and Lisa Forman, in their 2008 article Exploring synergies between human rights and public health ethics: A whole greater than the sum of its parts, to propose that the principles of human rights and public health ethics should be used in combination to develop norms for health action. This commentary reflects on the benefits as well as the difficulties that could arise from taking such an approach.

  6. Ethical issues of transplanting organs from transgenic animals into human beings.

    Science.gov (United States)

    Behnam Manesh, Shima; Omani Samani, Reza; Behnam Manesh, Shayan

    2014-01-01

    One of the most important applications of transgenic animals for medical purposes is to transplant their organs into human's body, an issue which has caused a lot of ethical and scientific discussions. we can divide the ethical arguments to two comprehensive groups; the first group which is known as deontological critiques (related to the action itself regardless of any results pointing the human or animal) and the second group, called the consequentialist critiques (which are directly pointing the consequences of the action). The latter arguments also can be divided to two subgroups. In the first one which named anthropocentrism, just humankind has inherent value in the moral society, and it studies the problem just from a human-based point of view while in second named, biocentrism all the living organism have this value and it deals specially with the problem from the animal-based viewpoint. In this descriptive-analytic study, ethical issues were retrieved from books, papers, international guidelines, thesis, declarations and instructions, and even some weekly journals using keywords related to transgenic animals, organ, and transplantation. According to the precautionary principle with the strong legal and ethical background, due to lack of accepted scientific certainties about the safety of the procedure, in this phase, transplanting animal's organs into human beings have the potential harm and danger for both human and animals, and application of this procedure is unethical until the safety to human will be proven.

  7. Ethics, Humanism and Poetry: Analysis of Nicolas Guillén Works

    Directory of Open Access Journals (Sweden)

    Iván Darío Moreno Acero

    2013-12-01

    Full Text Available Nicolás Guillén poetry is able to sound out the human and its condition. Besides, it portrays witnessed social phenomena. Thus, it is said that poetry leads to an ethical reflection on the human condition in the world. Hence, it has got a two-sided essence. First, as reasoning set depicting the daily horror and violence an individual deals with. Then, a significant and virtuous narrative that may lead to conceive better ways to inhabit the world. This paper analyzes three main Latin American philosophy topics in Nicolás Guillén works: the human deterioration amidst social, politic and economic conflicts, justice need and human reinvidication claimed by each conflict actor and the importance of listening to other narratives presenting ways to cope with horror and abolish it. In general, this article shows one of the results got by the research group: “Ethics and Literature: Narratives on the human. Nicolás Guillén poetry has images that can be useful for Ethics to enquire inhuman actions. It also holds utopian proposals to build up a fair society and ethic criteria concerning more human action and judgement.

  8. Ethical aspects of human embryonic stem cell research in the islamic world: positions and reflections.

    Science.gov (United States)

    Ilkilic, Ilhan; Ertin, Hakan

    2010-06-01

    Rapid technological developments in human embryonic stem cell research are holding promises of future new medical treatment for a range of currently incurable chronic diseases. At the same time, stem cell research using human embryos raises radically new, previously unimaginable ethical issues posing a dramatic challenge to humankind. By analysing the discourses on these ethical issues we can show that the cultural values and religious convictions of all stakeholders involved play a decisive role in formulating ethical positions. In the Islamic world, too, stem cell research using human embryos provokes new discussions about the moral status of the embryo according to Islamic ethical norms. In our paper we describe the theological and philosophical criteria used in this debate and discuss some ethical positions vis-à-vis embryonic stem cell research formulated in the Islamic world, including official regulations existing in some Muslim countries. While most of the existing literature in this field is primarily descriptive, the present paper endeavours to examine not only the arguments and their historical conditions as such; in addition, we will for the first time provide a critical reflection on the methodology underlying commonly held positions. In our view, this reflection is of paramount importance in establishing a straightforward constructive dialogue between different cultures and academic disciplines.

  9. Ethical issues surrounding the transplantation of human fetal tissues.

    Science.gov (United States)

    Hurd, R E

    1992-12-01

    Organ transplants have been one of the greatest advances in medicine. However, organs from living relatives or cadavers are in short supply, and many people die awaiting a donor organ. Increasing the donor pool by using organs from aborted fetuses has been proposed to increase the supply. In addition, there are benefits of using fetal tissue including its particular usefulness in children, the fact that it is not readily rejected, and its potential for growth. Guidelines for fetal research were issued in 1975, but a research moratorium was imposed in 1988 to allow study of ethical and legal issues. While the federal government delays in lifting the ban, several states have written laws governing experimentation with fetuses. Ethical arguments against using fetal tissue for organ transplant include a concern that this would create a branch of biomedicine which depends on the continuation of induced abortions. This could lead to neglect of research for other therapies. The timing and type of abortion should continue to benefit the mother, rather than the organ recipient. Ethicists debate whether or not use of aborted tissue implies complicity in the abortion process beyond that which exists for all members of a society which permits abortion. They also wonder whether knowing that some good could come of an abortion would influence a woman's decision to have one. Proposals to keep the use of fetal tissue ethical include banning the commercial use of sale of tissues, forbidding designation of the tissue recipient (to prevent harvesting fetal tissue for a relative), separating abortion counseling and management from harvesting of the tissue, and obtaining informed consent (perhaps from a proxy surrogate rather than from the mother) for the use of fetal tissue. When the medical and ethical communities have reached some consensus on these issues, crafted safeguards, and precluded conflicts of interest, then restrictions on government funding should be lifted. Whereas it

  10. Czech Journalists’ Refreshed Sense of Ethics in the Midst of Media Ownership Turmoil

    Directory of Open Access Journals (Sweden)

    Roman Hájek

    2015-12-01

    Full Text Available In recent years, the Czech Republic has seen the largest changes in media ownership since the early 1990s. Most striking was the purchase of one of the largest publishing houses Mafra by the tycoon Andrej Babiš in June 2013, followed by the takeover of the Czech branch of Ringier by other Czech businessmen later that year. The first case in particular instigated immense discussion about the economic and ethical crisis facing Czech journalism since Babiš is also a powerful political figure (currently the Minister of Finance. In response, a significant number of leading, well-known journalists left media owned by big business and launched projects of quality or “slow” journalism which had until that point been merely discussed theoretically. This paper—based on the results of the Czech part of the Worlds of Journalism Study project—addresses the shift in the ways journalists perceive their roles and ethical responsibilities before and after the 2013 ownership changes. We also present the manner in which these changes are reflected in emerging media projects. It seems that those journalists not affected by the ownership change tend to view journalism ethics and the ability of journalism to exert power more seriously than before.

  11. Convergent ethical issues in HIV/AIDS, tuberculosis and malaria vaccine trials in Africa: Report from the WHO/UNAIDS African AIDS Vaccine Programme's Ethics, Law and Human Rights Collaborating Centre consultation, 10-11 February 2009, Durban, South Africa

    National Research Council Canada - National Science Library

    Mamotte, Nicole; Wassenaar, Douglas; Koen, Jennifer; Essack, Zaynab

    2010-01-01

    .... In order to explore convergent ethical issues in HIV/AIDS, TB and malaria vaccine trials in Africa, the Ethics, Law and Human Rights Collaborating Centre of the WHO/UNAIDS African AIDS Vaccine...

  12. Reproductive cloning and human health: an ethical, international, and nursing perspective.

    Science.gov (United States)

    Sanchez-Sweatman, L R

    2000-03-01

    Human reproductive cloning came to the public's attention when Dolly, a sheep, was cloned in Scotland in 1997. This news quickly spread around the world causing both excitement at the possibilities that cloning techniques could offer, as well as apprehension about the ethical, social and legal implications should human reproductive cloning become possible. Many international organizations, such as the World Health Organization, the International Council of Nurses, and governments were concerned about the impact of human reproductive cloning on human health, dignity and human rights. To this end, many institutions have drafted resolutions, protocols and position statements outlining their concerns. This paper will outline some of the major ethical issues surrounding human reproductive cloning, the position of various international organizations and governments, and specifically the position of the International Council of Nurses.

  13. True or False, Process or Procedure: Parrhesia and a Consideration of Humanism, Subjectivity, and Ethics within Educational Research

    Science.gov (United States)

    Roof, David; Polush, Elena

    2016-01-01

    This paper seeks to examine ethics, humanism, and the concept of "parrhesia" ("pa???s?a") in the context of educational research. More specifically, it surveys Foucault's lectures on ethics to explore a framework for educational research that disrupts subjectivity and traditional forms of humanism while retaining a relational…

  14. The future of human embryonic stem cell research: addressing ethical conflict with responsible scientific research.

    Science.gov (United States)

    Gilbert, David M

    2004-05-01

    Embryonic stem (ES) cells have almost unlimited regenerative capacity and can potentially generate any body tissue. Hence they hold great promise for the cure of degenerative human diseases. But their derivation and the potential for misuse have raised a number of ethical issues. These ethical issues threaten to paralyze pubic funding for ES cell research, leaving experimentation in the hands of the private sector and precluding the public's ability to monitor practices, research alternatives, and effectively address the very ethical issues that are cause for concern in the first place. With new technology being inevitable, and the potential for abuse high, government must stay involved if the public is to play a role in shaping the direction of research. In this essay, I will define levels of ethical conflict that can be delineated by the anticipated advances in technology. From the urgent need to derive new ES cell lines with existing technology, to the most far-reaching goal of deriving genetically identical tissues from an adult patients cells, technology-specific ethical dilemmas can be defined and addressed. This staged approach provides a solid ethical framework for moving forward with ES cell research. Moreover, by anticipating the moral conflicts to come, one can predict the types of scientific advances that could overcome these conflicts, and appropriately direct federal funding toward these goals to offset potentially less responsible research directives that will inevitably go forward via private or foreign funding.

  15. The Human - Nature Relationship i n t he Context o f Theo - Centric Environmental Ethics

    Directory of Open Access Journals (Sweden)

    Gülşen YAYLI

    2015-07-01

    Full Text Available The environmental problems are one of the issues that intensively occupy the agenda of humankind. This fact mainly derives from the ambiguity of the s pan and the content of the issue. The concept of environmental problems can not be confined to th e soil, air and water pollution for the reason that it covers a scope wider than a classical pollution issues. Initially the form of the relations hip between h uman and nature has been relying on the “consumption at the level of content” which stands for a level that is enough to sustain the living. The perception of the nature used to be described with the metaphor of mother while natural environment was defined as the “mother earth”. However subsequent to natural environment definition of the Cartesian philosophy with its approach to the human nature relationship, the core metaphor to describe the natural environment has changed from the metaphor of “mother” to the “slave” which should serve by any means. The human - nature relationship within the context of ethics, both the parties an d their respective statues bear an importance. In terms of ethics of human - nature relationship, it is possible to mention three main approaches. First one is the anthropo - centric approach. Within the scope of historical process, human - nature relationship is addressed according to anthropo - centric ethics comprehension so human has remained at the center of discussion. Following the change of the perception regarding the issue of environment, new approaches have emerged that give emphasis not only on human beings but also others; on li ving and non - living beings with in the eco - system. In principle, this represents a departure from an anthropo - centric ethics to a new ethic approach which fall s into two categories, bio centric and eco - centric. The theo - centric ethics should also be included to these ethics approaches that are shaped within the sphere of positive sciences. The Abrahamic

  16. Mind the gap: Griffith University's approach to the governance of ethical conduct in human research.

    Science.gov (United States)

    Allen, Gary

    2007-01-01

    It is perhaps not coincidental that, at the same time the apparent institutional risks associated with the conduct of human research are increasing, so are the complaints from researchers about research ethics committees. Rather than seeking to implement systems that more efficiently catch wrong-doing, in 2003 Griffith University began implementing an alternative approach. This new approach focused on resourcing the reflective practice of researchers through every stage of their work--well before, and long after, they seek ethical clearance for that work. Institutions have a key role to play in human research ethics, and this can be usefully situated within the broader framework of the institution's governance framework. This paper summarises the new approach that Griffith University adopted in 2003, the implementation of this 'model', the experience to date, and the road ahead.

  17. The importance of ethic in the field of human tissue banking.

    Science.gov (United States)

    Morales Pedraza, Jorge; Herson, Marisa Roma

    2012-03-01

    A tissue bank is accountable before the community in fulfilling the expectations of tissue donors, their families and recipients. The expected output from the altruistic donation is that safe and high quality human tissue grafts will be provided for the medical treatment of patients. Thus, undertakings of tissue banks have to be not only authorised and audited by national competent health care authorities, but also comply with a strong ethical code, a code of practices and ethical principles. Ethical practice in the field of tissue banking requires the setting of principles, the identification of possible deviations and the establishment of mechanisms that will detect and hinder abuses that may occur during the procurement, processing and distribution of human tissues for transplantation. The opinions and suggestions manifested by the authors in this paper may not be necessarily a reflection of those within the institutions or community they are linked to.

  18. Ethical Issues of Transplanting Organs from Transgenic Animals into Human Beings

    Directory of Open Access Journals (Sweden)

    Shima Behnam Manesh

    2014-04-01

    Full Text Available One of the most important applications of transgenic animals for medical purposes is to transplant their organs into human’s body, an issue which has caused a lot of ethical and scientific discussions. we can divide the ethical arguments to two comprehensive groups; the first group which is known as deontological critiques (related to the action itself regardless of any results pointing the human or animal and the second group, called the consequentialist critiques (which are directly pointing the consequences of the action. The latter arguments also can be divided to two subgroups. In the first one which named anthropocentrism, just humankind has inherent value in the moral society, and it studies the problem just from a human-based point of view while in second named, biocentrism all the living organism have this value and it deals specially with the problem from the animal-based viewpoint. In this descriptive-analytic study, ethical issues were retrieved from books, papers, international guidelines, thesis, declarations and instructions, and even some weekly journals using keywords related to transgenic animals, organ, and transplantation. According to the precautionary principle with the strong legal and ethical background, due to lack of accepted scientific certainties about the safety of the procedure, in this phase, transplanting animal’s organs into human beings have the potential harm and danger for both human and animals, and application of this procedure is unethical until the safety to human will be proven.

  19. Still Human: A Call for Increased Focus on Ethical Standards in Cadaver Research.

    Science.gov (United States)

    Bach, Michelle C

    2016-12-01

    Research on human cadavers is an important mechanism of scientific progress and comprises a large industry in the United States. However, despite its importance and influence, there is little ethical or regulatory oversight of cadaver-based research. This lack of transparency raises important ethical questions. Thus, this paper serves as a call for ethicists and regulators to pay increased attention to cadaver research. I argue that cadaver research ought to be considered a subset of human subjects research and held accountable to higher ethical standards. After describing current practices, I argue that oversight of cadaver research as a form of human subjects research is appropriate because cadaver research is similar to other types of human research, participants in cadaver research incur risks of harm, and a current lack of oversight has allowed the cadaver industry to entice research participation through ethically questionable practices. This paper urges greater dialogue among human subjects research ethicists and regulators about what constitutes appropriate protections for participants in cadaver research.

  20. Engineer Ethics Education that Treated Safety Problem to Promote Development of General Human Competence and Independent Engineer

    Science.gov (United States)

    Hotta, Genji

    The human race came to expect the engineer‧s international activity by an international extension of the risk. The engineer should provide with “Overall ability” and “Independent ability” to answer the demand of the society. The engineer ethics education is effective to the acquisition of the ability that the society demands. Because the engineer ethics education teaches the engineer to develop “Ethics action as the individual” to “Ethics activity as the enterprise” . In the point of development of the comprehensive capacity, it can be said that the engineer ethics education is training that supports the action power that accomplishes the social responsibility. However, it is easy to make the engineer ethics education a polite fiction. Then, we propose to take the safety problem to the ethics education for the prevention of making to the polite fiction of the education.

  1. Heterogeneity of Human Research Ethics Committees and Research Governance Offices across Australia: An observational study

    Directory of Open Access Journals (Sweden)

    Elisabeth De Smit

    2016-02-01

    Full Text Available Background Conducting ethically grounded research is a fundamental facet of all investigations. Nevertheless, the administrative burdens of current ethics review are substantial, and calls have been made for a reduction in research waste. Aims To describe the heterogeneity in administration and documentation required by Human Research Ethics Committees (HRECs and Research Governance Offices (RGOs across Australia. Methods In establishing a nationwide study to investigate the molecular aetiology of Giant Cell Arteritis (GCA, for which archived pathological specimens from around Australia are being recruited, we identified variation across separate HREC and RGO requirements. Submission paperwork and correspondence from each collaborating site and its representative office for research were reviewed. This data was interrogated to evaluate differences in current guidelines. Results Twenty-five pathology departments across seven Australian States collaborated in this study. All states, except Victoria, employed a single ethics review model. There was discrepancy amongst HRECs as to which application process applied to our study: seven requested completion of a “National Ethics Application Form” and three a “Low Negligible Risk” form. Noticeable differences in guidelines included whether electronic submission was sufficient. There was variability in the total number of documents submitted (range five to 22 and panel review turnaround time (range nine to 136 days. Conclusion We demonstrate the challenges and illustrate the heavy workload involved in receiving widespread ethics and governance approval across Australia. We highlight the need to simplify, homogenise, and nationalise human ethics for non-clinical trial studies. Reducing unnecessary administration will enable investigators to achieve research aims more efficiently

  2. The use of animal tissues alongside human tissue: Cultural and ethical considerations.

    Science.gov (United States)

    Kaw, Anu; Jones, D Gareth; Zhang, Ming

    2016-01-01

    Teaching and research facilities often use cadaveric material alongside animal tissues, although there appear to be differences in the way we handle, treat, and dispose of human cadaveric material compared to animal tissue. This study sought to analyze cultural and ethical considerations and provides policy recommendations on the use of animal tissues alongside human tissue. The status of human and animal remains and the respect because of human and animal tissues were compared and analyzed from ethical, legal, and cultural perspectives. The use of animal organs and tissues is carried out within the context of understanding human anatomy and function. Consequently, the interests of human donors are to be pre-eminent in any policies that are enunciated, so that if any donors find the presence of animal remains unacceptable, the latter should not be employed. The major differences appear to lie in differences in our perceptions of their respective intrinsic and instrumental values. Animals are considered to have lesser intrinsic value and greater instrumental value than humans. These differences stem from the role played by culture and ethical considerations, and are manifested in the resulting legal frameworks. In light of this discussion, six policy recommendations are proposed, encompassing the nature of consent, respect for animal tissues as well as human remains, and appropriate separation of both sets of tissues in preparation and display. © 2015 Wiley Periodicals, Inc.

  3. Ethical reflection and psychotherapy.

    Science.gov (United States)

    Vyskocilová, Jana; Prasko, Jan

    2013-01-01

    Theories of ethics and ethical reflection may be applied to both theory and practice in psychotherapy. There is a natural affinity between ethics and psychotherapy. Psychotherapy practice is concerned with human problems, dilemmas and emotions related to both one's own and other people's values. Ethics is also concerned with dilemmas in human thinking and with how these dilemmas reflect other individuals' values. Philosophical reflection itself is not a sufficient basis for the ethics of psychotherapy but it may aid in exploring attitudes related to psychotherapy, psychiatry and health care. PubMed, Web of Science and Scopus databases were searched for articles containing the keywords "psychotherapy", "ethics", "therapeutic relationship" and "supervision". The search was conducted by repeating the terms in various combinations without language or time restrictions. Also included were data from monographs cited in reviews. The resulting text is a review with conclusions concerning ethical aspects of psychotherapy. The ability to behave altruistically, sense for justice and reciprocity and mutual help are likely to be genetically determined as dispositions to be later developed by upbringing or to be formed or deformed by upbringing. Early experiences lead to formation of ethical attitudes which are internalized and then applied to both one's own and other people's behavior. Altruistic behavior has a strong impact on an individual's health and its acceptance may positively influence the pathophysiological mechanisms underlying numerous diseases. Ethical theory and reflection, however, may be applied to both theory and practice of psychotherapy in a conscious, targeted and thoughtful manner. In everyday practice, psychotherapists and organizations must necessarily deal with conscious conflicts between therapeutic possibilities, clients' wishes, their own as well as clients' ideas and the real world. Understanding one's own motives in therapy is one of the aims of a

  4. The Use of Ethical Frameworks for Implementing Science as a Human Endeavour in Year 10 Biology

    Science.gov (United States)

    Yap, Siew Fong; Dawson, Vaille

    2014-01-01

    This research focuses on the use of ethical frameworks as a pedagogical model for socio-scientific education in implementing the "Science as a Human Endeavour" (SHE) strand of the Australian Curriculum: Science in a Year 10 biology class in a Christian college in metropolitan Perth, Western Australia. Using a case study approach, a mixed…

  5. Genetic Testing and Its Implications: Human Genetics Researchers Grapple with Ethical Issues.

    Science.gov (United States)

    Rabino, Isaac

    2003-01-01

    Contributes systematic data on the attitudes of scientific experts who engage in human genetics research about the pros, cons, and ethical implications of genetic testing. Finds that they are highly supportive of voluntary testing and the right to know one's genetic heritage. Calls for greater genetic literacy. (Contains 87 references.) (Author/NB)

  6. Applied Ethics in Nowadays Society

    OpenAIRE

    Tomita CIULEI

    2013-01-01

    This special issue is dedicated to Nowadays Applied Ethics in Society, and falls in the field of social sciences and humanities, being hosted both theoretical approaches and empirical research in various areas of applied ethics. Applied ethics analyzes of a series of morally concrete situations of social or professional practice in order to make / adopt decisions. In the field of applied ethics are integrated medical ethics, legal ethics, media ethics, professional ethics, environmental ethic...

  7. Applied Ethics in Nowadays Society

    OpenAIRE

    Tomita CIULEI

    2013-01-01

    This special issue is dedicated to Nowadays Applied Ethics in Society, and falls in the field of social sciences and humanities, being hosted both theoretical approaches and empirical research in various areas of applied ethics. Applied ethics analyzes of a series of morally concrete situations of social or professional practice in order to make / adopt decisions. In the field of applied ethics are integrated medical ethics, legal ethics, media ethics, professional ethics, environmental ethic...

  8. Ethics and methods for biological rhythm research on animals and human beings.

    Science.gov (United States)

    Portaluppi, Francesco; Smolensky, Michael H; Touitou, Yvan

    2010-10-01

    This article updates the ethical standards and methods for the conduct of high-quality animal and human biological rhythm research, which should be especially useful for new investigators of the rhythms of life. The editors of Chronobiology International adhere to and endorse the Code of Conduct and Best Practice Guidelines of the Committee On Publication Ethics (COPE), which encourages communication of such updates at regular intervals in the journal. The journal accepts papers representing original work, no part of which was previously submitted for publication elsewhere, except as brief abstracts, as well as in-depth reviews. The majority of research papers published in Chronobiology International entails animal and human investigations. The editors and readers of the journal expect authors of submitted manuscripts to have made an important contribution to the research of biological rhythms and related phenomena using ethical methods/procedures and unbiased, accurate, and honest reporting of findings. Authors of scientific papers are required to declare all potential conflicts of interest. The journal and its editors endorse compliance of investigators to the Guide for the Care and Use of Laboratory Animals of the Institute for Laboratory Animal Research of the National Research Council, relating to the conduct of ethical research on laboratory and other animals, and the principles of the Declaration of Helsinki of the World Medical Association, relating to the conduct of ethical research on human beings. The peer review of manuscripts by Chronobiology International thus includes judgment as to whether or not the protocols and methods conform to ethical standards. Authors are expected to show mastery of the basic methods and procedures of biological rhythm research and proper statistical assessment of data, including the appropriate application of time series data analyses, as briefly reviewed in this article. The journal editors strive to consistently achieve

  9. Human somatic cell nuclear transfer and reproductive cloning: an Ethics Committee opinion.

    Science.gov (United States)

    2016-04-01

    This document presents arguments that conclude that it is unethical to use somatic cell nuclear transfer (SCNT) for infertility treatment due to concerns about safety; the unknown impact of SCNT on children, families, and society; and the availability of other ethically acceptable means of assisted reproduction. This document replaces the ASRM Ethics Committee report titled, "Human somatic cell nuclear transfer and cloning," last published in Fertil Steril 2012;98:804-7. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. The search for truth and freedom: ethical issues surrounding human cloning and stem cell research.

    Science.gov (United States)

    Bruce, Alex

    2002-02-01

    The reality of cloning and stem cell research has provoked wonder, fear and anger. These developments have the potential fundamentally to alter humanity. But how well informed is the range of views being expressed? Is progress being threatened by understandable but uninformed fears? Or are scientists rushing toward an ethical abyss, so concerned with what they can do that they never stop to ask what they should do? This article identifies some of the fears and hopes surrounding cloning and stem cell research. It aims to provoke ethical debate in evaluating such research.

  11. Ethical Issues Surrounding the Use of Modern Human Remains for Research in South Africa.

    Science.gov (United States)

    Briers, N; Dempers, J J

    2017-02-01

    Chapter 8 of the South African National Health Act 61 of 2003 (NHA) that deals with the donation of human tissue was promulgated in 2012. The new Act is perceived to impose restrictions on low-risk research involving human remains. This study aimed to identify the issues raised by a research ethics committee (REC) when reviewing protocols where human remains are used as data source. REC minutes from 2009 to 2014 were reviewed, and issues raised by the committee were categorized. In total, 127 protocols submitted to the committee over 6 years involved human remains. Queries relating to science (22.2%) and administration (18.9%) were the most common, whereas queries relating to legal issues constituted only 10.2%. Ethical issues centered on informed consent regarding sensitive topics such as HIV, DNA, and deceased children. The change in legislation did not change the number or type of legal issues identified by the REC.

  12. Human genome education model project. Ethical, legal, and social implications of the human genome project: Education of interdisciplinary professionals

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, J.O. [Alliance of Genetic Support Groups, Chevy Chase, MD (United States); Lapham, E.V. [Georgetown Univ., Washington, DC (United States). Child Development Center

    1996-12-31

    This meeting was held June 10, 1996 at Georgetown University. The purpose of this meeting was to provide a multidisciplinary forum for exchange of state-of-the-art information on the human genome education model. Topics of discussion include the following: psychosocial issues; ethical issues for professionals; legislative issues and update; and education issues.

  13. Documentation of ethical conduct of human subject research published in Saudi medical journals.

    Science.gov (United States)

    Al-Gaai, E A; Hammami, M M; Al Eidan, M

    2012-07-01

    We evaluated the documentation of ethical conduct (obtaining institutional review board approval and consent and following ethical guidelines) of human subject research studies published in Saudi Arabian medical journals between 1979 and 2007. Studies were classified as retrospective, prospective noninterventional, interventional or survey/interview. Of 1838 studies published in 286 journal issues of 11 Saudi Arabian medical journals, only 0.9% documented the ethical guidelines followed, with a significantly higher rate for studies published after year 2000 (1.7%). Of 821 studies requiring institutional review board approval, 8.6% documented obtaining the approval and informed consent, with a significantly higher rate for interventional studies (19.4%), post-year 2000 studies (19.7%) and studies performed outside Saudi Arabia (15.9%). The low documentation rate suggests editor's lack of rigor and/or investigators' ignorance of guidelines. The higher documentation rate after year 2000 suggests an ongoing improvement.

  14. Bioethics methods in the ethical, legal, and social implications of the human genome project literature.

    Science.gov (United States)

    Walker, Rebecca L; Morrissey, Clair

    2014-11-01

    While bioethics as a field has concerned itself with methodological issues since the early years, there has been no systematic examination of how ethics is incorporated into research on the Ethical, Legal and Social Implications (ELSI) of the Human Genome Project. Yet ELSI research may bear a particular burden of investigating and substantiating its methods given public funding, an explicitly cross-disciplinary approach, and the perceived significance of adequate responsiveness to advances in genomics. We undertook a qualitative content analysis of a sample of ELSI publications appearing between 2003 and 2008 with the aim of better understanding the methods, aims, and approaches to ethics that ELSI researchers employ. We found that the aims of ethics within ELSI are largely prescriptive and address multiple groups. We also found that the bioethics methods used in the ELSI literature are both diverse between publications and multiple within publications, but are usually not themselves discussed or employed as suggested by bioethics method proponents. Ethics in ELSI is also sometimes undistinguished from related inquiries (such as social, legal, or political investigations).

  15. System Ethics: New Approach to Guarantee Human Rights

    Institute of Scientific and Technical Information of China (English)

    HE YING

    2011-01-01

    @@ Respect for and protection of human rights is an issue of common concern nowadays.In 2004, China added "The state respects and protects human rights"to Article 33 of its Constitution in the form of amendment.

  16. Core competencies for health care ethics consultants: in search of professional status in a post-modern world.

    Science.gov (United States)

    Engelhardt, H Tristram

    2011-09-01

    The American Society for Bioethics and the Humanities (ASBH) issued its Core Competencies for Health Care Ethics Consultation just as it is becoming ever clearer that secular ethics is intractably plural and without foundations in any reality that is not a social-historical construction (ASBH Core Competencies for Health Care Ethics Consultation, 2nd edn. American Society for Bioethics and Humanities, Glenview, IL, 2011). Core Competencies fails to recognize that the ethics of health care ethics consultants is not ethics in the usual sense of a morally canonical ethics. Its ethics is the ethics established at law and in enforceable health care public policy in a particular jurisdiction. Its normativity is a legal normativity, so that the wrongness of violating this ethics is simply the legal penalties involved and the likelihood of their being imposed. That the ethics of ethics consultation is that ethics legally established accounts for the circumstance that the major role of hospital ethics consultants is as quasi-lawyers giving legal advice, aiding in risk management, and engaging in mediation. It also indicates why this collage of roles has succeeded so well. This article shows how moral philosophy as it was reborn in the 13th century West led to the ethics of modernity and then finally to the ethics of hospital ethics consultation. It provides a brief history of the emergence of an ethics that is after morality. Against this background, the significance of Core Competencies must be critically reconsidered.

  17. Human Genome Diversity Project. Summary of planning workshop 3(B): Ethical and human-rights implications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    The third planning workshop of the Human Genome Diversity Project was held on the campus of the US National Institutes of Health in Bethesda, Maryland, from February 16 through February 18, 1993. The second day of the workshop was devoted to an exploration of the ethical and human-rights implications of the Project. This open meeting centered on three roundtables, involving 12 invited participants, and the resulting discussions among all those present. Attendees and their affiliations are listed in the attached Appendix A. The discussion was guided by a schedule and list of possible issues, distributed to all present and attached as Appendix B. This is a relatively complete, and thus lengthy, summary of the comments at the meeting. The beginning of the summary sets out as conclusions some issues on which there appeared to be widespread agreement, but those conclusions are not intended to serve as a set of detailed recommendations. The meeting organizer is distributing his recommendations in a separate memorandum; recommendations from others who attended the meeting are welcome and will be distributed by the meeting organizer to the participants and to the Project committee.

  18. Ethical implications of the human-animal bond in the laboratory.

    Science.gov (United States)

    Russow, Lilly-Marlene

    2002-01-01

    This analysis of the moral implications of a human-animal bond in a research setting begins by describing a set of criteria that delineate the human-animal bond in general and form the foundation on which moral issues rest. Questions about if, when, and how such bonds are formed are discussed briefly; the discussion focuses on how the concept of a human-animal bond fits into standard moral theories. The conclusion is that impartial theories such as utilitarianism and deontological theories must be supplemented with an ethics of caring and that the moral duties engendered by the human-animal bond are best identified with such a supplemented theory.

  19. Global Ethics Applied: Global Ethics, Economic Ethics

    OpenAIRE

    Stückelberger, Christoph

    2016-01-01

    Global Ethics Applied’ in four volumes is a reader of 88 selected articles from the author on 13 domains: Vol. 1 Global Ethics, Economic Ethics; Vol. 2 Environmental Ethics; Vol. 3 Development Ethics, Political Ethics, Dialogue and Peace Ethics, Innovation and Research Ethics, Information and Communication Ethics; Vol. 4 Bioethics and Medical Ethics, Family Ethics and Sexual Ethics, Leadership Ethics, Theological Ethics and Ecclesiology, Methods of Ethics. It concludes with the extended Bibli...

  20. e-Government Ethics : a Synergy of Computer Ethics, Information Ethics, and Cyber Ethics

    OpenAIRE

    Arief Ramadhan; Dana Indra Sensuse; Aniati Murni Arymurthy

    2011-01-01

    Ethics has become an important part in the interaction among humans being. This paper specifically discusses applied ethics as one type of ethics. There are three applied ethics that will be reviewed in this paper, i.e. computer ethics, information ethics, and cyber ethics. There are two aspects of the three applied ethics that were reviewed, i.e. their definition and the issues associated with them. The reviewing results of the three applied ethics are then used for defining e-Government eth...

  1. e-Government Ethics : a Synergy of Computer Ethics, Information Ethics, and Cyber Ethics

    OpenAIRE

    Arief Ramadhan; Dana Indra Sensuse; Aniati Murni Arymurthy

    2011-01-01

    Ethics has become an important part in the interaction among humans being. This paper specifically discusses applied ethics as one type of ethics. There are three applied ethics that will be reviewed in this paper, i.e. computer ethics, information ethics, and cyber ethics. There are two aspects of the three applied ethics that were reviewed, i.e. their definition and the issues associated with them. The reviewing results of the three applied ethics are then used for defining e-Government eth...

  2. AN AGENDA OF MORALITY FOR BUSINESS ETHICS

    Directory of Open Access Journals (Sweden)

    ANCA PUP

    2010-01-01

    Full Text Available The aim of this paper work is to conclude a short confirmation for business ethics. A redundant argument for business ethics, should, in our opinion start from the philosophical field. A major problem with business ethics is the foreclosing of philosophy, society and politics from its debate area. Before understanding the common sense for business ethics, we have to know how to act in a moral way. It is important to understand the identity of the human being, its signification and goals. Therefore the first part of this research enclose to philosophy, pointing out three aspects concerted to morality. We consider that only after a proper analyze of the human being, we can argue for business ethics and its implication in different area. Otherwise “business” becomes a problem for “ethics” and “ethics” become a problem for “business”.

  3. Ethical questions concerning research on human embryos, embryonic stem cells and chimeras.

    Science.gov (United States)

    Bobbert, Monika

    2006-12-01

    Research using human embryos and embryonic stem cells is viewed as important for various reasons. Apart from questions concerning legal regulations, numerous ethical objections are raised pertaining to the use of surplus embryos from reproductive medicine as well as the creation of embryos and stem cells through cloning. In the hopes of avoiding ethical problems, alternatives have been proposed including the extraction of egg cells from "dead" embryos derived from in vitro fertilization procedures, the extraction of pluripotent stem cells from blastocysts, technologies such as "altered nuclear transfer" (ANT) and "oocyte-assisted reprogramming" (ANT-OAR) as well as parthenogenesis. Initial ethical assessments show that certain questions pertaining to such strategies have remained unanswered. Furthermore, with the help of new or more differentiated biotechnological procedures, it is possible to create chimeras and hybrids in which human and non-human cells are combined. Human-animal chimeras, in which gametes or embryonic tissue have been mixed with embryonic or adult stem cells, demonstrate a different "quality" and "degree of penetration" from those produced in previous experiments. Not only does this have consequences regarding questions of patentability, this situation also raises fundamental questions concerning the human being's self image, the concept of person, identity and species and the moral rights and duties that are connected with such concepts. There is a need for legal regulation, on the national as well as the international level.

  4. Human and animal research guidelines: aligning ethical constructs with new scientific developments.

    Science.gov (United States)

    Ferdowsian, Hope

    2011-10-01

    Both human research and animal research operate within established standards and procedures. Although the human research environment has been criticized for its sometimes inefficient and imperfect process, reported abuses of human subjects in research served as the impetus for the establishment of the Nuremberg Code, Declaration of Helsinki, and the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and the resulting Belmont Report. No similar, comprehensive and principled effort has addressed the use of animals in research. Although published policies regarding animal research provide relevant regulatory guidance, these policies have not emerged from the process of specifying consistent and reasoned ethical principles. The lack of a fundamental effort to explore the ethical issues and principles regarding the use of animals in research has led to unclear and disparate policies. Recent studies have increased our understanding of animal cognition and emotion, suggesting that animals' potential for experiencing a wide variety of harms, such as pain and fear, is greater than has been previously appreciated. Furthermore, relationships between methods of captivity and certain laboratory procedures and the resulting adverse physical, social and psychological effects have been established. In light of this information, current protections may need to be reconsidered and modified. This paper explores the historical convergence and divergence in the creation of human and animal research guidelines, as well as opportunities to align ethical frameworks with new scientific discoveries.

  5. Where are human subjects in Big Data research? The emerging ethics divide

    Directory of Open Access Journals (Sweden)

    Jacob Metcalf

    2016-06-01

    Full Text Available There are growing discontinuities between the research practices of data science and established tools of research ethics regulation. Some of the core commitments of existing research ethics regulations, such as the distinction between research and practice, cannot be cleanly exported from biomedical research to data science research. Such discontinuities have led some data science practitioners and researchers to move toward rejecting ethics regulations outright. These shifts occur at the same time as a proposal for major revisions to the Common Rule—the primary regulation governing human-subjects research in the USA—is under consideration for the first time in decades. We contextualize these revisions in long-running complaints about regulation of social science research and argue data science should be understood as continuous with social sciences in this regard. The proposed regulations are more flexible and scalable to the methods of non-biomedical research, yet problematically largely exclude data science methods from human-subjects regulation, particularly uses of public datasets. The ethical frameworks for Big Data research are highly contested and in flux, and the potential harms of data science research are unpredictable. We examine several contentious cases of research harms in data science, including the 2014 Facebook emotional contagion study and the 2016 use of geographical data techniques to identify the pseudonymous artist Banksy. To address disputes about application of human-subjects research ethics in data science, critical data studies should offer a historically nuanced theory of “data subjectivity” responsive to the epistemic methods, harms and benefits of data science and commerce.

  6. Where are human subjects in Big Data research? The emerging ethics divide

    Directory of Open Access Journals (Sweden)

    Jacob Metcalf

    2016-06-01

    Full Text Available There are growing discontinuities between the research practices of data science and established tools of research ethics regulation. Some of the core commitments of existing research ethics regulations, such as the distinction between research and practice, cannot be cleanly exported from biomedical research to data science research. Such discontinuities have led some data science practitioners and researchers to move toward rejecting ethics regulations outright. These shifts occur at the same time as a proposal for major revisions to the Common Rule—the primary regulation governing human-subjects research in the USA—is under consideration for the first time in decades. We contextualize these revisions in long-running complaints about regulation of social science research and argue data science should be understood as continuous with social sciences in this regard. The proposed regulations are more flexible and scalable to the methods of non-biomedical research, yet problematically largely exclude data science methods from human-subjects regulation, particularly uses of public datasets. The ethical frameworks for Big Data research are highly contested and in flux, and the potential harms of data science research are unpredictable. We examine several contentious cases of research harms in data science, including the 2014 Facebook emotional contagion study and the 2016 use of geographical data techniques to identify the pseudonymous artist Banksy. To address disputes about application of human-subjects research ethics in data science, critical data studies should offer a historically nuanced theory of “data subjectivity” responsive to the epistemic methods, harms and benefits of data science and commerce.

  7. Engineering Substantially Prolonged Human Lifespans: Biotechnological Enhancement and Ethics

    NARCIS (Netherlands)

    Derkx, P.H.J.M.

    2006-01-01

    Substantial extension of the human lifespan has recently become a subject of lively debate. One reason for this is the completion in 2001 of the Human Genome Project and the experimental avenues for biogerontological research it has opened. Another is recent theoretical progress in biogerontology.

  8. Some thoughts on the diffusion of psychoanalysis: the group dimension, ethics and the sense of identity.

    Science.gov (United States)

    Namer, Albert

    2011-12-01

    In this paper the author questions some of the ways in which psychoanalysis is passed on to the wider public, one of which is sometimes evocative of the sales promotion of a consumer product in contemporary society. This methodology does not give sufficiently deep prior thought to the eventual consequences of side effects. The detailed exposition of clinical cases, for example, raises sensitive ethical issues, even when anonymity is preserved. Although it is true that making information about Freud's theories more widely available may indeed encourage people to think about training as psychoanalysts, it is noticeable that this process is sometimes considered to be a form of training in itself. Some participants feel that acquiring a psychoanalytical vocabulary and reading clinical reports form a sufficient basis for practising thereafter as psychotherapists, both in institutional contexts and in private practice. The absence of group work on the part of the organizers might explain why closer study is not made of the methodologies of transmission and the different levels that it involves. This is sometimes due to the absence of a common object, formed within and by the group, and to the emergence of manic defences in the group.

  9. [The gift of human body's products: philosophical and ethical aspects].

    Science.gov (United States)

    Baertschi, B

    2014-09-01

    In continental Europe, there is a very strong moral condemnation against putting parts or products of the human body on sale-and, consequently, against putting sperms and oocytes on sale. Only a gift is morally permissible. The situation is different in Anglo-Saxon countries. Who is right? Above all, it must be noticed that two views of the human body are facing each other here: for the first, the human body is a part of the person (so, it partakes of the person's dignity), whereas for the second, the human body is a possession of the person (the person is the owner of his/her body). In my opinion, the argument of dignity comes up against serious objections, and the property argument is more consistent. However, it does not follow that it would be judicious to put parts and products of the human body for sale on a market.

  10. Ethical Concerns About Human Genetic Enhancement in the Malay Science Fiction Novels.

    Science.gov (United States)

    Isa, Noor Munirah; Hj Safian Shuri, Muhammad Fakhruddin

    2017-03-09

    Advancements in science and technology have not only brought hope to humankind to produce disease-free offspring, but also offer possibilities to genetically enhance the next generation's traits and capacities. Human genetic enhancement, however, raises complex ethical questions, such as to what extent should it be allowed? It has been a great challenge for humankind to develop robust ethical guidelines for human genetic enhancement that address both public concerns and needs. We believe that research about public concerns is necessary prior to developing such guidelines, yet the issues have not been thoroughly investigated in many countries, including Malaysia. Since the novel often functions as a medium for the public to express their concerns, this paper explores ethical concerns about human genetic enhancement expressed in four Malay science fiction novels namely Klon, Leksikon Ledang, Transgenesis Bisikan Rimba and Transgenik Sifar. Religion has a strong influence on the worldview of the Malays therefore some concerns such as playing God are obviously religious. Association of the negative image of scientists as well as the private research companies with the research on human genetic enhancement reflects the authors' concerns about the main motivations for conducting such research and the extent to which such research will benefit society.

  11. Feto-maternal biology and ethics of human society

    Science.gov (United States)

    Paulesu, Luana; Ietta, Francesca; Petraglia, Felice

    2005-01-01

    The growing interest in human reproduction and the identity of the embryo have prompted us to bring some considerations to the attention of scientists. In particular, we focus on the interactive relationship between the embryo and the mother starting from the earliest stages of development. Principles governing the acceptance and growth of the embryo in the uterus may represent a model for mutual tolerance and peaceful co-existence in human society. PMID:16232317

  12. Feto-maternal biology and ethics of human society

    Directory of Open Access Journals (Sweden)

    Petraglia Felice

    2005-10-01

    Full Text Available Abstract The growing interest in human reproduction and the identity of the embryo have prompted us to bring some considerations to the attention of scientists. In particular, we focus on the interactive relationship between the embryo and the mother starting from the earliest stages of development. Principles governing the acceptance and growth of the embryo in the uterus may represent a model for mutual tolerance and peaceful co-existence in human society.

  13. On Creative Sense of Ethic Educators%高校德育主体的创新观念

    Institute of Scientific and Technical Information of China (English)

    谭建平; 陈湘俊

    2001-01-01

    高等教育培养学生的创新精神和创新能力是时代发展的需要。具备创新精神与创新观念是高校德育主体正确履行其职能和职责的先决条件。创新是德育主体实施创新教育应具备的一种基本能力。高校德育主体必须更新教育观念,不断提高创新素质,才能更好地实施创新教育。%Fostering college students' creative ability is a requirement of our times in higher education. Ethical educators must possess a sense of creation and an ability of creative education, which is a prerequisite for them to play an important role and perform functions in the campus creative education. To meet the needs of educational reform, the instructors should renew their efforts to qualify themselves for the post and fulfil the goal.

  14. Rethinking research ethics.

    Science.gov (United States)

    Rhodes, Rosamond

    2010-10-01

    Contemporary research ethics policies started with reflection on the atrocities perpetrated upon concentration camp inmates by Nazi doctors. Apparently, as a consequence of that experience, the policies that now guide human subject research focus on the protection of human subjects by making informed consent the centerpiece of regulatory attention. I take the choice of context for policy design, the initial prioritization of informed consent, and several associated conceptual missteps, to have set research ethics off in the wrong direction. The aim of this paper is to sort out these confusions and their implications and to offer instead a straightforward framework for considering the ethical conduct of human subject research. In the course of this discussion I clarify different senses of autonomy that have been confounded and present more intelligible justifications for informed consent. I also take issue with several of the now accepted dogmas that govern research ethics. These include: the primacy of informed consent, the protection of the vulnerable, the substitution of beneficence for research's social purpose, and the introduction of an untenable distinction between innovation and research.

  15. The ethical concept of the fetus as a patient and the beginning of human life

    OpenAIRE

    Kurjak, Asim; MARIA CARRERA, JOSE; McCullough, Laurence B.; Chervenak, Frank A.

    2009-01-01

    »When does human life begin?« is not one question, but three. The first question is, »When does human biological life begin?,« and is a scientific question. A brief review of embryology is provided to answer this question. The second question is, »When do obligations to protect human life begin?,« and is a question of general theological and philosophical ethics. A brief review of major world religions and philosophy is provided to answer this question has no settled answer and therefore invo...

  16. Ethical aspects of creating human-nonhuman chimeras capable of human gamete production and human pregnancy.

    Science.gov (United States)

    Palacios-González, César

    2015-01-01

    In this paper I explore some of the moral issues that could emerge from the creation of human-nonhuman chimeras (HNH-chimeras) capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that could emerge from the fact that a HNH-chimera could become pregnant with a human conceptus. I focus on two sets of problems: problems that would arise by virtue of the fact that a human is gestated by a nonhuman creature, and problems that would emerge from the fact that such pregnancies could affect the health of the HNH-chimera.

  17. Knowledge, Ethics and Choices: Theorizing the Functional Matrix of Literature as a Humanities Discipline

    OpenAIRE

    2016-01-01

    One may inaugurate the contemporary post-theory era with thinking beyond the theoretical aspects of literature. Or, in other words, it may facilitate a revision of literary theories in terms of exploring their functionality. But, a complex question involved here is, what may be its implications. How may it affect various disciplines especially the Humanities which are, unlike Sciences, deal with the abstract issues like truth, reality, ethicality, justice and many more like that? With these q...

  18. Recognition, Reification, and Practices of Forgetting: Ethical Implications of Human Resource Management

    OpenAIRE

    Islam, Gazi

    2012-01-01

    International audience; This article examines the ethical framing of employment in contemporary human resource management (HRM). Using Axel Honneth's theory of recognition and classical critical notions of reification, I contrast recognition and reifying stances on labor. The recognition approach embeds work in its emotive and social particu-larity, positively affirming the basic dignity of social actors. Reifying views, by contrast, exhibit a forgetfulness of recognition, removing action fro...

  19. Ethical, legal and economic issues raised by the use of human tissue in postgenomic research.

    Science.gov (United States)

    Reymond, M A; Steinert, R; Escourrou, J; Fourtanier, G

    2002-01-01

    Ethical, legal and economic framework issues concerning human samples, genetic data and bioresources are rapidly evolving. In most cases, international standards have not been defined. National legislations on the use and exploitation of human sample collections differ widely. Legislations relating to intellectual property rights, access to database information for public or private bodies, of national or foreign origin, are similarly diverse. Importation and exportation rules, concerning in particular data protection, biosafety and protection of individual rights, have not always been defined. This article makes a short assessment of the legal, ethical and economic framework in selected EC countries (Germany, France and UK), and compares them with the conditions in the USA. On the basis of the information collected, it is obvious that the use of human cells, tissues and organs in medical research has to be considered as a global, worldwide question. Such use has profound ethical, cultural and economic consequences not only in the country of origin, but also globally. Biotechnology and pharmaceutical companies conducting research with human samples are facing different framework conditions in the area of data protection, policy measures, economic support, exportation, etc., that already influence trade activities and investments of such firms at the international level. Over the 3 last years, a trend towards harmonization can be recognized: the World Health Organization has recognized the problems of postgenomic medical research as a priority. The OECD has created a taskforce on centers for biological resources. Biobanks are a common theme of the French and the German National Ethic Councils. A lack of international harmonization and consistency might not only present a challenge to biotechnology and pharmaceutical companies, but can also endanger the goals the laws and regulations seek to achieve. Copyright 2002 S. Karger AG, Basel

  20. Ethical and Human Rights Foundations of Health Policy: Lessons from Comprehensive Reform in Mexico.

    Science.gov (United States)

    Frenk, Julio; Gómez-Dantés, Octavio

    2015-12-10

    This paper discusses the use of an explicit ethical and human rights framework to guide a reform intended to provide universal and comprehensive social protection in health for all Mexicans, independently of their socio-economic status or labor market condition. This reform was designed, implemented, and evaluated by making use of what Michael Reich has identified as the three pillars of public policy: technical, political, and ethical. The use of evidence and political strategies in the design and negotiation of the Mexican health reform is briefly discussed in the first part of this paper. The second part examines the ethical component of the reform, including the guiding concept and values, as well as the specific entitlements that gave operational meaning to the right to health care that was enshrined in Mexico's 1983 Constitution. The impact of this rights-based health reform, measured through an external evaluation, is discussed in the final section. The main message of this paper is that a clear ethical framework, combined with technical excellence and political skill, can deliver major policy results.

  1. It Takes More Than Ethics

    Directory of Open Access Journals (Sweden)

    Chris Simpson

    2001-05-01

    things as care of others and environment, along with some sense of humility, giving, gratitude, purpose, distant vision and wardenship. How can ethical guidelines transcend into being 'inspirational' guidelines, independent of occupation? Is this not the realm of higher values? And if so, is this essential to the fundamental progress of human-kind? It may well be so. A few more simple observations and tools are offered that could be of assistance.

  2. Making Ethics Come Alive

    Science.gov (United States)

    McQueeney, Edward

    2006-01-01

    Making ethics relevant to students in a business communications course continues to be a challenge. Classroom practitioners have long noted the difficulties in surmounting the contradictions students sense in business ethics instruction. Furthermore, students often perceive ethics to be largely irrelevant to the skills necessary for success in…

  3. Exploring synergies between human rights and public health ethics: A whole greater than the sum of its parts

    Directory of Open Access Journals (Sweden)

    Nixon Stephanie

    2008-01-01

    Full Text Available Abstract Background The fields of human rights and public health ethics are each concerned with promoting health and elucidating norms for action. To date, however, little has been written about the contribution that these two justificatory frameworks can make together. This article explores how a combined approach may make a more comprehensive contribution to resolving normative health issues and to advancing a normative framework for global health action than either approach made alone. We explore this synergy by first providing overviews of public health ethics and of international human rights law relevant to health and, second, by articulating complementarities between human rights and public health ethics. Discussion We argue that public health ethics can contribute to human rights by: (a reinforcing the normative claims of international human rights law, (b strengthening advocacy for human rights, and (c bridging the divide between public health practitioners and human rights advocates in certain contemporary health domains. We then discuss how human rights can contribute to public health ethics by contributing to discourses on the determinants of health through: (a definitions of the right to health and the notion of the indivisibility of rights, (b emphasis on the duties of states to progressively realize the health of citizens, and (c recognition of the protection of human rights as itself a determinant of health. We also discuss the role that human rights can play for the emergent field of public health ethics by refocusing attention on the health and illness on marginalized individuals and populations. Summary Actors within the fields of public health, ethics and human rights can gain analytic tools by embracing the untapped potential for collaboration inherent in such a combined approach.

  4. Ethical issues of the research on human embryonic stem cells.

    Science.gov (United States)

    Hotta, Yoshitaro

    2008-09-01

    This paper examines the debate on human embryonic stem cell (hES) research. In Japan, as in many Western countries, the moral status of the human embryo has been the main focus. There is a dichotomy between the advocates of research on hES cells and the advocates of the dignity of the embryos. Advocates of research on hES cells claim that the act of abandoning the embryo and the act of using it for research have the same moral status. Critics of research using embryos reject this position, claiming that the embryo has a status incommensurable with other values. This paper points out that the standpoint of the woman providing the embryos has been overlooked in this discussion.

  5. Reflections on the ethics of recruiting foreign-trained human resources for health

    Directory of Open Access Journals (Sweden)

    Labonté Ronald

    2011-01-01

    Full Text Available Abstract Background Developed countries' gains in health human resources (HHR from developing countries with significantly lower ratios of health workers have raised questions about the ethics or fairness of recruitment from such countries. By attracting and/or facilitating migration for foreign-trained HHR, notably those from poorer, less well-resourced nations, recruitment practices and policies may be compromising the ability of developing countries to meet the health care needs of their own populations. Little is known, however, about actual recruitment practices. In this study we focus on Canada (a country with a long reliance on internationally trained HHR and recruiters working for Canadian health authorities. Methods We conducted interviews with health human resources recruiters employed by Canadian health authorities to describe their recruitment practices and perspectives and to determine whether and how they reflect ethical considerations. Results and discussion We describe the methods that recruiters used to recruit foreign-trained health professionals and the systemic challenges and policies that form the working context for recruiters and recruits. HHR recruiters' reflections on the global flow of health workers from poorer to richer countries mirror much of the content of global-level discourse with regard to HHR recruitment. A predominant market discourse related to shortages of HHR outweighed discussions of human rights and ethical approaches to recruitment policy and action that consider global health impacts. Conclusions We suggest that the concept of corporate social responsibility may provide a useful approach at the local organizational level for developing policies on ethical recruitment. Such local policies and subsequent practices may inform public debate on the health equity implications of the HHR flows from poorer to richer countries inherent in the global health worker labour market, which in turn could influence

  6. The role of veterinarians in equestrian sport: a comparative review of ethical issues surrounding human and equine sports medicine.

    Science.gov (United States)

    Campbell, Madeleine L H

    2013-09-01

    Veterinarians have a key role in providing medical care for sports horses during and between competitions, but the standard client:veterinarian relationship that exists in companion and production animal medicine is distorted by the involvement of third parties in sports medicine, resulting in distinct ethical dilemmas which warrant focused academic attention. By comparing the existing literature on human sports medicine, this article reviews the ethical dilemmas which face veterinarians treating equine athletes, and the role of regulators in contributing to or resolving those dilemmas. Major ethical dilemmas occur both between and during competitions. These include conflicts of responsibility, conflicts between the need for client confidentiality and the need to share information in order to maximise animal welfare, and the need for an evidence base for treatment. Although many of the ethical problems faced in human and equine sports medicine are similar, the duty conferred upon a veterinarian by the licensing authority to ensure the welfare of animals committed to his or her care requires different obligations to those of a human sports medicine doctor. Suggested improvements to current practice which would help to address ethical dilemmas in equine sports medicine include an enhanced system for recording equine injuries, the use of professional Codes of Conduct and Codes of Ethics to establish acceptable responses to common ethical problems, and insistence that treatment of equine athletes is evidence-based (so far as possible) rather than economics-driven.

  7. The role of veterinarians in equestrian sport: A comparative review of ethical issues surrounding human and equine sports medicine☆

    Science.gov (United States)

    Campbell, Madeleine L.H.

    2013-01-01

    Veterinarians have a key role in providing medical care for sports horses during and between competitions, but the standard client:veterinarian relationship that exists in companion and production animal medicine is distorted by the involvement of third parties in sports medicine, resulting in distinct ethical dilemmas which warrant focused academic attention. By comparing the existing literature on human sports medicine, this article reviews the ethical dilemmas which face veterinarians treating equine athletes, and the role of regulators in contributing to or resolving those dilemmas. Major ethical dilemmas occur both between and during competitions. These include conflicts of responsibility, conflicts between the need for client confidentiality and the need to share information in order to maximise animal welfare, and the need for an evidence base for treatment. Although many of the ethical problems faced in human and equine sports medicine are similar, the duty conferred upon a veterinarian by the licensing authority to ensure the welfare of animals committed to his or her care requires different obligations to those of a human sports medicine doctor. Suggested improvements to current practice which would help to address ethical dilemmas in equine sports medicine include an enhanced system for recording equine injuries, the use of professional Codes of Conduct and Codes of Ethics to establish acceptable responses to common ethical problems, and insistence that treatment of equine athletes is evidence-based (so far as possible) rather than economics-driven. PMID:23773811

  8. Human Behavior Recognition Using Foot Pressure Sensing Shoes

    Science.gov (United States)

    Sugimoto, Chika; Ozaki, Kenji; Ezoe, Ryosuke; Hosaka, Hiroshi; Yamato, Hiroyuki

    To recognize human behavior in unlimited environments, sensing shoes for measuring foot pressure distribution were developed. Seven pressure sensors were installed on an insole, and a measurement module was embedded in the shoe. An analysis for discriminating the user's movements from the foot pressure distribution was examined, considering the movements, walking, running, standing, sitting, going upstairs and downstairs, and cycling. These seven actions were discriminated using feature quantities such as the average, standard deviation, maximum, and difference deviation extracted from the data of three sensors by discriminant analysis. The evaluation results showed highly accurate behavior recognition based on foot pressure at some points. In addition, by canonical discriminant analysis, six discriminant functions which classify the seven actions with an accuracy of 100% were derived by using feature quantities extracted from five sensors. The results confirmed that discriminant analysis can be used for automatically recognizing human behaviors based on foot pressure data.

  9. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs.

    Science.gov (United States)

    Verrinder, Joy M; Ostini, Remo; Phillips, Clive J C

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was compared with that of students in non-animal related disciplines of human medicine and arts. All students (n = 531) completed a moral reasoning test, the VetDIT, with animal and human scenarios. When compared with reasoning on human ethics issues, the combined group of students evaluating animal ethics issues showed higher levels of Universal Principles reasoning, lower levels of Personal Interest reasoning and similar levels of Maintaining Norms reasoning. Arts students showed more personal interest reasoning than students in most animal-related programs on both animal and human ethics issues, and less norms-based reasoning on animal ethics issues. Medical students showed more norms-based reasoning on animal ethics issues than all of the animal-related groups. There were no differences in principled reasoning on animal ethics issues between program groups. This has implications for animal-related professions and education programs showing that students' preference for principled reasoning on animal ethics issues is not unique to animal-related disciplines, and highlighting the need to develop student (and professional) capacity to apply principled reasoning to address ethics issues in animal industries to reduce the risk of moral distress.

  10. A Touch Sensing Technique Using the Effects of Extremely Low Frequency Fields on the Human Body.

    Science.gov (United States)

    Elfekey, Hatem; Bastawrous, Hany Ayad; Okamoto, Shogo

    2016-12-02

    Touch sensing is a fundamental approach in human-to-machine interfaces, and is currently under widespread use. Many current applications use active touch sensing technologies. Passive touch sensing technologies are, however, more adequate to implement low power or energy harvesting touch sensing interfaces. This paper presents a passive touch sensing technique based on the fact that the human body is affected by the surrounding extremely low frequency (ELF) electromagnetic fields, such as those of AC power lines. These external ELF fields induce electric potentials on the human body-because human tissues exhibit some conductivity at these frequencies-resulting in what is called AC hum. We therefore propose a passive touch sensing system that detects this hum noise when a human touch occurs, thus distinguishing between touch and non-touch events. The effectiveness of the proposed technique is validated by designing and implementing a flexible touch sensing keyboard.

  11. A Touch Sensing Technique Using the Effects of Extremely Low Frequency Fields on the Human Body

    Directory of Open Access Journals (Sweden)

    Hatem Elfekey

    2016-12-01

    Full Text Available Touch sensing is a fundamental approach in human-to-machine interfaces, and is currently under widespread use. Many current applications use active touch sensing technologies. Passive touch sensing technologies are, however, more adequate to implement low power or energy harvesting touch sensing interfaces. This paper presents a passive touch sensing technique based on the fact that the human body is affected by the surrounding extremely low frequency (ELF electromagnetic fields, such as those of AC power lines. These external ELF fields induce electric potentials on the human body—because human tissues exhibit some conductivity at these frequencies—resulting in what is called AC hum. We therefore propose a passive touch sensing system that detects this hum noise when a human touch occurs, thus distinguishing between touch and non-touch events. The effectiveness of the proposed technique is validated by designing and implementing a flexible touch sensing keyboard.

  12. Citizenship, human rights, and dementia: Towards a new embodied relational ethic of sexuality.

    Science.gov (United States)

    Kontos, Pia; Grigorovich, Alisa; Kontos, Alexis P; Miller, Karen-Lee

    2016-05-01

    Sexual citizenship and sexual rights scholarship have made important contributions to broadening citizenship and more fully accommodating rights related to sexuality. However, this scholarship has concentrated primarily on the sexuality and intimacy-related needs of younger people and those who are not cognitively impaired. Consequently, it has inadvertently served to marginalize persons living with dementia who reside in long-term residential care settings. We argue that supporting sexual rights for persons with dementia requires a particular human rights ontology for citizenship-one that recognizes that corporeality is a fundamental source of self-expression, interdependence, and reciprocal engagement. This is an ontology that underpins our model of relational citizenship and that grounds our articulation of an ethic of embodied relational sexuality. In our view, this ethic offers important direction for the development of policy, legislation, and clinical guidelines to support sexual rights for persons with dementia in long-term residential care.

  13. An Ethics Perspective on Transcranial Magnetic Stimulation (TMS and Human Neuromodulation

    Directory of Open Access Journals (Sweden)

    Judy Illes

    2006-01-01

    Full Text Available This paper concerns the ethics of human neuromodulation using transcranial magnetic stimulation (TMS. We examine the challenges of modulating the brain with TMS through the research ethics lens and in clinical medicine for treating frank pathology, primarily in psychiatric diseases. We also consider contemporary issues raised in the neuroethics literature about managing unexpected findings, and relate these to TMS and to other frontier neurotechnology that is becoming openly available in the public domain. We argue that safety and informed consent are of paramount importance for TMS, but that personal values and sociocultural factors must also be considered when examining the promise of this technology and applications that ought to be highlighted for extra precautions.

  14. IS ETHICAL HACKING ETHICAL?

    OpenAIRE

    MUHAMMAD NUMAN ALI KHAN; DANISH JAMIL,

    2011-01-01

    This paper explores the ethics behind ethical hacking and whether there are problems that lie with this new field of work. Since ethical hacking has been a controversial subject over the past few years, the question remains of the true intentions of ethical hackers. The paper also looks at ways in which future research could be looked intoto help keep ethical hacking, ethical.

  15. Case-Based Learning as Pedagogy for Teaching Information Ethics Based on the Dervin Sense-Making Methodology

    Science.gov (United States)

    Dow, Mirah J.; Boettcher, Carrie A.; Diego, Juana F.; Karch, Marziah E.; Todd-Diaz, Ashley; Woods, Kristine M.

    2015-01-01

    The purpose of this mixed methods study is to determine the effectiveness of case-based pedagogy in teaching basic principles of information ethics and ethical decision making. Study reports results of pre- and post-assessment completed by 49 library and information science (LIS) graduate students at a Midwestern university. Using Creswell's…

  16. Sense of presence and anxiety during virtual social interactions between a human and virtual humans

    OpenAIRE

    Nexhmedin Morina; Willem-Paul Brinkman; Dwi Hartanto; Emmelkamp, Paul M. G.

    2014-01-01

    Virtual reality exposure therapy (VRET) has been shown to be effective in treatment of anxiety disorders. Yet, there is lack of research on the extent to which interaction between the individual and virtual humans can be successfully implanted to increase levels of anxiety for therapeutic purposes. This proof-of-concept pilot study aimed at examining levels of the sense of presence and anxiety during exposure to virtual environments involving social interaction with virtual humans and using d...

  17. Sense of presence and anxiety during virtual social interactions between a human and virtual humans

    OpenAIRE

    Nexhmedin Morina; Willem-Paul Brinkman; Dwi Hartanto; Emmelkamp, Paul M. G.

    2014-01-01

    Virtual reality exposure therapy (VRET) has been shown to be effective in treatment of anxiety disorders. Yet, there is lack of research on the extent to which interaction between the individual and virtual humans can be successfully implanted to increase levels of anxiety for therapeutic purposes. This proof-of-concept pilot study aimed at examining levels of the sense of presence and anxiety during exposure to virtual environments involving social interaction with virtual humans and using d...

  18. Societal and ethical issues in human biomonitoring – a view from science studies

    Directory of Open Access Journals (Sweden)

    Bauer Susanne

    2008-01-01

    Full Text Available Abstract Background Human biomonitoring (HBM has rapidly gained importance. In some epidemiological studies, the measurement and use of biomarkers of exposure, susceptibility and disease have replaced traditional environmental indicators. While in HBM, ethical issues have mostly been addressed in terms of informed consent and confidentiality, this paper maps out a larger array of societal issues from an epistemological perspective, i.e. bringing into focus the conditions of how and what is known in environmental health science. Methods In order to analyse the effects of HBM and the shift towards biomarker research in the assessment of environmental pollution in a broader societal context, selected analytical frameworks of science studies are introduced. To develop the epistemological perspective, concepts from "biomedical platform sociology" and the notion of "epistemic cultures" and "thought styles" are applied to the research infrastructures of HBM. Further, concepts of "biocitizenship" and "civic epistemologies" are drawn upon as analytical tools to discuss the visions and promises of HBM as well as related ethical problematisations. Results In human biomonitoring, two different epistemological cultures meet; these are environmental science with for instance pollution surveys and toxicological assessments on the one hand, and analytical epidemiology investigating the association between exposure and disease in probabilistic risk estimation on the other hand. The surveillance of exposure and dose via biomarkers as envisioned in HBM is shifting the site of exposure monitoring to the human body. Establishing an HBM platform faces not only the need to consider individual decision autonomy as an ethics issue, but also larger epistemological and societal questions, such as the mode of evidence demanded in science, policy and regulation. Conclusion The shift of exposure monitoring towards the biosurveillance of human populations involves fundamental

  19. Methodological and ethical issues in research using social media: a metamethod of Human Papillomavirus vaccine studies.

    Science.gov (United States)

    Gustafson, Diana L; Woodworth, Claire F

    2014-12-02

    Online content is a primary source of healthcare information for internet-using adults and a rich resource for health researchers. This paper explores the methodological and ethical issues of engaging in health research using social media. A metamethod was performed on systematically selected studies that used social media as a data source for exploring public awareness and beliefs about Human Papillomaviruses (HPV) and HPV vaccination. Seven electronic databases were searched using a variety of search terms identified for each of three concepts: social media, HPV vaccine, and research method. Abstracts were assessed for eligibility of inclusion; six studies met the eligibility criteria and were subjected to content analysis. A 10-item coding scheme was developed to assess the clarity, congruence and transparency of research design, epistemological and methodological underpinnings and ethical considerations. The designs of the six selected studies were sound, although most studies could have been more transparent about how they built in rigor to ensure the trustworthiness and credibility of findings. Statistical analysis that intended to measure trends and patterns did so without the benefit of randomized sampling and other design elements for ensuring generalizability or reproducibility of findings beyond the specified virtual community. Most researchers did not sufficiently engage virtual users in the research process or consider the risk of privacy incursion. Most studies did not seek ethical approval from an institutional research board or permission from host websites or web service providers. The metamethod exposed missed opportunities for using the dialogical character of social media as well as a lack of attention to the unique ethical issues inherent in operating in a virtual community where social boundaries and issues of public and private are ambiguous. This suggests the need for more self-conscious and ethical research practices when using social media

  20. Reconcilable differences? Human diversity, cultural relativity, and sense of community.

    Science.gov (United States)

    Townley, Greg; Kloos, Bret; Green, Eric P; Franco, Margarita M

    2011-03-01

    Sense of community (SOC) is one of the most widely used and studied constructs in community psychology. As proposed by Sarason in (The Psychological sense of community: prospects for a community psychology, Jossey-Bass, San Francisco, 1974), SOC represents the strength of bonding among community members. It is a valuable component of community life, and it has been linked to positive mental health outcomes, citizen participation, and community connectedness. However, promotion of SOC can become problematic in community psychology praxis when it conflicts with other core values proposed to define the field, namely values of human diversity, cultural relativity, and heterogeneity of experience and perspective. Several commentators have noted that promotion of SOC can conflict with multicultural diversity because it tends to emphasize group member similarity and appears to be higher in homogeneous communities. In this paper, we introduce the idea of a community-diversity dialectic as part of praxis and research in community psychology. We argue that systematic consideration of cultural psychology perspectives can guide efforts to address a community-diversity dialectic and revise SOC formulations that ultimately will invigorate community research and action. We provide a working agenda for addressing this dialectic, proposing that systematic consideration of the creative tension between SOC and diversity can be beneficial to community psychology.

  1. Admixed human embryos and stem cells: legislative, ethical and scientific advances.

    Science.gov (United States)

    Bahadur, G; Iqbal, M; Malik, S; Sanyal, A; Wafa, R; Noble, R

    2008-01-01

    This paper examines the regulatory framework currently governing the creation of animal-human hybrids and chimera embryos in stem cell research, and some of the ethical implications of such research. It discusses the findings of a recent government select committee that considered the topic. It considers the debate around the precise definition of a human embryo, and whether such hybrids therefore fall within the remit of the Human Fertilisation and Embryology Authority. It outlines the advantages of such hybrids, in lessening the need for human egg donors, as well as the moral objections to species boundary violation. It calls for an examination of the scientific benefits of such research to inform debate on the question, and argues for the need to take genuine account of the public's views on this matter.

  2. The Ethics of Traditional Chinese and Western Herbal Medicine Research: Views of Researchers and Human Ethics Committees in Australia

    Directory of Open Access Journals (Sweden)

    Caroline A. Smith

    2011-01-01

    Full Text Available Despite the growth of traditional Chinese medicine (TCM and western herbal medicine (WHM research in Australia, little is known about how ethics committees (HRECs assess the ethics of TCM or WHM research. The objectives of this study were to examine the experiences of TCM and WHM researchers and HRECs with the evaluation of ethics applications. Two cross-sectional surveys were undertaken of HRECs and TCM and WHM researchers in Australia. Anonymous self-completion questionnaires were administered to 224 HRECs and 117 researchers. A response confirming involvement in TCM or WHM research applications was received from 20 HRECs and 42 researchers. The most frequent ethical issues identified by HRECs related to herbal products including information gaps relating to mode of action of herbal medicines and safety when combining herbal ingredients. Researchers concurred that they were frequently requested to provide additional information on multiple aspects including safety relating to the side effects of herbs and herb-drug interactions. Overall adherence with the principles of ethical conduct was high among TCM and WHM researchers although our study did identify the need for additional information regarding assessment of risk and risk management.

  3. [Is an act of human love the in vitro fertilization? A proposal ethical analysis].

    Science.gov (United States)

    García Sánchez, Emilio

    2014-01-01

    Since 1978, when the first test tube baby, Louis Brown, was born, thousands of children have been born every year through in vitro fertilization. Many families keep attending fertility clinics in order to receive some treatment for their infertility problems and have a child. Children born in this way are worthy human beings. Their parents love them and devote themselves to their children admirably, showing real parental love. However, does this loving kindness justify, from an ethical point of view, any way of desiring and having a son or daughter? Is it really an act of human love to long for a child and satisfy this desire using artificial methods? Is it equally human and worthy to wish them choosing in vitro fertilization than to wish them through an intimate and loving relationship, in which the child emerges as a result of interpersonal donation? I answer these questions by analyzing the ethics proposal formulated by Rhonheimer and Carrasco de Paula. In short, only the intimate and loving sexual union between a man and a woman -as long as it is unconditional love- may be the dignity cause of the existence of a human being. And such union and unconditional requirement are absent in vitro fertilization.

  4. [The Ethics Committee meeting in Belgium May 7, 2004, on human experimentation].

    Science.gov (United States)

    Dresse, A

    2005-01-01

    The European directive 2001/20/EC concerning the performance or clinical trials has been transposed in the Belgian law of May 7, 2004, entitled "Loi relative aux expérimentations sur la personne humaine" (Moniteur belge, May 18, 2004)". The range of the law is larger than those of the directive. Several new elements must be underlined: 1. Any experimentation on a human being may only begin if the promoter received a positive advice from an ethical committee according to the provision of the law. 2. For multicentric assays, a single opinion, identical for all the participating centres must be obtained. This implies a close dialogue between the ethical committees. A central committee is proposed by the industrial promoter. Each clinical trial of a drug must have a unique identification number obtained at the European agency for the evaluation of medicinal products (EMEA). 3. Taking into account the fear of the pharmaceutical industry that some clinical studies could be "delocalized", the authorities accepted to reduce to twenty- eight days (instead of 60) the delay granted to the ethical committee in order to produce their single opinion. 4. The law of May 7, 2004, clearly defines the dispositions related to the protection of the participants. Particular dispositions are foreseen for the protection of minors, incapable adults and patients in emergency. 5. The promoter endorses, even without fault, the responsibility of the damage caused to the participant or his descendants. An insurance covering this risk must be contracted.

  5. Applied Ethics in Nowadays Society

    Directory of Open Access Journals (Sweden)

    Tomita CIULEI

    2013-12-01

    Full Text Available This special issue is dedicated to Nowadays Applied Ethics in Society, and falls in the field of social sciences and humanities, being hosted both theoretical approaches and empirical research in various areas of applied ethics. Applied ethics analyzes of a series of morally concrete situations of social or professional practice in order to make / adopt decisions. In the field of applied ethics are integrated medical ethics, legal ethics, media ethics, professional ethics, environmental ethics, business ethics etc. Classification-JEL: A23

  6. The Belmont Report. Ethical principles and guidelines for the protection of human subjects of research.

    Science.gov (United States)

    2014-01-01

    On July 12, 1974, the National Research Act (Pub. L. 93-348) was signed into law, thereby creating the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. One of the charges to the Commission was to identify the basic ethical principles that should underlie the conduct of biomedical and behavioral research involving human subjects and to develop guidelines which should be followed to assure that such research is conducted in accordance with those principles. In carrying out the above, the Commission was directed to consider: (a) the boundaries between biomedical and behavioral research and the accepted and routine practice of medicine, (b) the role of assessment of risk-benefit criteria in the determination of the appropriateness of research involving human subjects, (c) appropriate guidelines for the selection of human subjects for participation in such research and (d) the nature and definition of informed consent in various research settings. The Belmont Report attempts to summarize the basic ethical principles identified by the Commission in the course of its deliberations. It is the outgrowth of an intensive four-day period of discussions that were held in February 1976 at the Smithsonian Institution's Belmont Conference Center supplemented by the monthly deliberations of the Commission that were held over a period of nearly four years. It is a statement of basic ethical principles and guidelines that should assist in resolving the ethical problems that surround the conduct of research with human subjects. By publishing the Report in the Federal Register, and providing reprints upon request, the Secretary intends that it may be made readily available to scientists, members of Institutional Review Boards, and Federal employees. The two-volume Appendix, containing the lengthy reports of experts and specialists who assisted the Commission in fulfilling this part of its charge, is available as DHEW Publication No. (OS

  7. At the Limit: Introducing Energy with Human Senses

    Science.gov (United States)

    Stinken, Lisa; Heusler, Stefan; Carmesin, Hans-Otto

    2016-12-01

    Energy belongs to the core ideas of the physics curriculum. But at the same time, energy is one of the most complex topics in science education since it occurs in multiple ways, such as motion, sound, light, and thermal energy. It can neither be destroyed nor created, but only converted. Due to the variety of relevant scales and abstractness of the term energy, the question arises how to introduce energy at the introductory physics level. The aim of this article is to demonstrate how the concept of energy can become meaningful in the context of the human senses. Three simple experiments to investigate the minimal amount of energy that is required to generate a sensory perception are presented. In this way students can learn that even different sensory perceptions can be compared by using energy as the unifying concept.

  8. Tracking the Evolution of Smartphone Sensing for Monitoring Human Movement.

    Science.gov (United States)

    del Rosario, Michael B; Redmond, Stephen J; Lovell, Nigel H

    2015-07-31

    Advances in mobile technology have led to the emergence of the "smartphone", a new class of device with more advanced connectivity features that have quickly made it a constant presence in our lives. Smartphones are equipped with comparatively advanced computing capabilities, a global positioning system (GPS) receivers, and sensing capabilities (i.e., an inertial measurement unit (IMU) and more recently magnetometer and barometer) which can be found in wearable ambulatory monitors (WAMs). As a result, algorithms initially developed for WAMs that "count" steps (i.e., pedometers); gauge physical activity levels; indirectly estimate energy expenditure and monitor human movement can be utilised on the smartphone. These algorithms may enable clinicians to "close the loop" by prescribing timely interventions to improve or maintain wellbeing in populations who are at risk of falling or suffer from a chronic disease whose progression is linked to a reduction in movement and mobility. The ubiquitous nature of smartphone technology makes it the ideal platform from which human movement can be remotely monitored without the expense of purchasing, and inconvenience of using, a dedicated WAM. In this paper, an overview of the sensors that can be found in the smartphone are presented, followed by a summary of the developments in this field with an emphasis on the evolution of algorithms used to classify human movement. The limitations identified in the literature will be discussed, as well as suggestions about future research directions.

  9. Tracking the Evolution of Smartphone Sensing for Monitoring Human Movement

    Directory of Open Access Journals (Sweden)

    Michael B. del Rosario

    2015-07-01

    Full Text Available Advances in mobile technology have led to the emergence of the “smartphone”, a new class of device with more advanced connectivity features that have quickly made it a constant presence in our lives. Smartphones are equipped with comparatively advanced computing capabilities, a global positioning system (GPS receivers, and sensing capabilities (i.e., an inertial measurement unit (IMU and more recently magnetometer and barometer which can be found in wearable ambulatory monitors (WAMs. As a result, algorithms initially developed for WAMs that “count” steps (i.e., pedometers; gauge physical activity levels; indirectly estimate energy expenditure and monitor human movement can be utilised on the smartphone. These algorithms may enable clinicians to “close the loop” by prescribing timely interventions to improve or maintain wellbeing in populations who are at risk of falling or suffer from a chronic disease whose progression is linked to a reduction in movement and mobility. The ubiquitous nature of smartphone technology makes it the ideal platform from which human movement can be remotely monitored without the expense of purchasing, and inconvenience of using, a dedicated WAM. In this paper, an overview of the sensors that can be found in the smartphone are presented, followed by a summary of the developments in this field with an emphasis on the evolution of algorithms used to classify human movement. The limitations identified in the literature will be discussed, as well as suggestions about future research directions.

  10. Religious morality (and secular humanism) in Western civilization as precursors to medical ethics: A historic perspective

    Science.gov (United States)

    Faria, Miguel A.

    2015-01-01

    In discussing bioethics and the formulation of neuroethics, the question has arisen as to whether secular humanism should be the sole philosophical guiding light, to the exclusion of any discussion (or even mention) of religious morality, in professional medical ethics. In addition, the question has arisen as to whether freedom or censorship should be part of medical (and neuroscience) journalism. Should independent medical journals abstain from discussing certain issues, or should only the major medical journals — i.e., the New England Journal of Medicine (NEJM), the Journal of the American Medical Association (JAMA) or Lancet — be heard, speaking with one “consensual,” authoritative voice? This issue is particularly important in controversial topics impacting medical politics — e.g., public health policy, socio-economics, bioethics, and the so-called redistributive justice in health care. Should all sides be heard when those controversial topics are discussed or only a consensual (monolithic) side? This historical review article discusses those issues and opts for freedom in medical and surgical practice as well as freedom in medical journalism, particularly in opinion pieces such as editorials, commentaries, or letters to the editor, as long as they relate to medicine and, in our special case, to neuroscience and neurosurgery. After answering those questions, and in response to a critical letter to the editor, this review article then expounds comprehensively on the historical and philosophical origins of ethics and religious morality. Necessarily, we discuss the Graeco-Roman legacy and the Judeo-Christian inheritance in the development of ethics and religious morality in Western civilization and their impact on moral conduct in general and on medical and neuroscience ethics in particular. PMID:26110085

  11. Religious morality (and secular humanism in Western civilization as precursors to medical ethics: A historic perspective

    Directory of Open Access Journals (Sweden)

    Miguel A Faria

    2015-01-01

    Full Text Available In discussing bioethics and the formulation of neuroethics, the question has arisen as to whether secular humanism should be the sole philosophical guiding light, to the exclusion of any discussion (or even mention of religious morality, in professional medical ethics. In addition, the question has arisen as to whether freedom or censorship should be part of medical (and neuroscience journalism. Should independent medical journals abstain from discussing certain issues, or should only the major medical journals - i.e., the New England Journal of Medicine (NEJM, the Journal of the American Medical Association (JAMA or Lancet - be heard, speaking with one "consensual," authoritative voice? This issue is particularly important in controversial topics impacting medical politics - e.g., public health policy, socio-economics, bioethics, and the so-called redistributive justice in health care. Should all sides be heard when those controversial topics are discussed or only a consensual (monolithic side? This historical review article discusses those issues and opts for freedom in medical and surgical practice as well as freedom in medical journalism, particularly in opinion pieces such as editorials, commentaries, or letters to the editor, as long as they relate to medicine and, in our special case, to neuroscience and neurosurgery. After answering those questions, and in response to a critical letter to the editor, this review article then expounds comprehensively on the historical and philosophical origins of ethics and religious morality. Necessarily, we discuss the Graeco-Roman legacy and the Judeo-Christian inheritance in the development of ethics and religious morality in Western civilization and their impact on moral conduct in general and on medical and neuroscience ethics in particular.

  12. [Sulfonamide-research on human subjects in Nazi concentration camps: a critical re-evaluation of the epistemological and ethical dimension].

    Science.gov (United States)

    Roelcke, Volker

    2009-01-01

    Existing scholarship on the experiments performed in concentration camps beginning in 1942 on the value of sulfonamides in treatment of wound infections, in which inmates were used as experimental subjects, maintains that not only were the experiments ethically and legally completely reprehensible and unacceptable, but that they were also bad science in the sense that they were investigating questions that had already been resolved by valid medical research. In contrast to this, the paper argues on the basis of contemporary publications that the value of sulfonamides in the treatment of wound infections, including gas gangrene infections, was not yet established, that is, that the questions pursued by the experiments had not been resolved. It also argues that regarding their "design" and methodical principles, the experiments directly followed the rationality of contemporary clinical trials and animal experiments. However, for the step from animal to the human experiment, the experimental "objects" were only in regard to their body, but not to their individuality and subjectivity regarded as "human". In a concluding section, the paper lines out some implications for an adequate historical reconstruction of medical research on humans, in particular the importance of a combined focus on the scientific rationality as well as explicit or implicit value hierarchies. Further, the article points to the potential impact of such a revised image of the sulfonamide experiments for present day debates on the ethics of medical research.

  13. Questioning the concept of risk in ethical guidelines for research in the humanities and social sciences in Public Health.

    Science.gov (United States)

    Bosi, Maria Lúcia Magalhães

    2015-09-01

    This article discusses the use of the concept of risk in ethical guidelines directed to research in the humanities and social sciences (CHS), suggesting an alternative to that concept. In Public Health field (PH), risk assumes a peculiar semantics, closely linked to the idea of calculation and predictability, according to the disciplinary bases that support it. This circumstance makes incongruous its use in initiatives justified precisely by strong distinctions between biomedical and social research, as ilustrated by specific guidelines for CHS, especially to the qualitative approach. The authors do not seek to redefine risk, operating a conceptual transit, but to sustain an effective conceptual distance within these specific guidelines, keeping congruence with the objectives pursued by its construction. Taking risk in the quantitative sense, still hegemonic in PH, overlooks important dimensions, reifying the use of this concept in situations where uncertainty, unpredictability, intersubjectivity inherent to the processes beyond the calculation and measurement, as in the case of a significant portion of the research in CHS. Alternatively, it is suggested to replace the expression level of risk, as also appears in Brazilian resolutions.

  14. [Exactly what is ethical nursing care? the perspective of the clinical humanities].

    Science.gov (United States)

    Yu, An-Bang

    2014-10-01

    As Taiwan enters the post-modern era of professional medical care, a host of issues relating to nursing care are becoming increasingly pressing. On the one hand, the wide range of ailments of body and mind requiring treatment is placing a major financial burden on the national health care system. On the other hand, few hospitals are able to provide "comprehensive care of body and mind." In addition to primary prevention, the most effective way to reduce the overall cost of medical care is to effectively bring volunteer caregivers (those who have an "ethical connection" with the patient, i.e., family, friends, neighbors, volunteers, etc.) into all levels of the caregiving process. Moreover, as medical ethics becomes increasingly focused on the well-being of the patient, more attention is being given to the healing relationship itself. Due to its ability to swiftly relieve a wide variety of ailments, the Western medical model has become widely accepted in Asia. Yet, a patient may feel a greater sense of healing when treatment is based on the principles of ethical caregiving. For example, in the way it quickly relieves the prevailing symptoms, psychiatric medication is like a freeway. By contrast, volunteer caregiving is more like a local road, which may be slower, but eventually takes one all the way home. Thus, making nursing care more person-centered and indigenized gives the patient a sense of not only being cured, but also being "cared for." However, for a long time the theory and practice of nursing education in Taiwan has been based on the Western model of nursing. In this model nursing is treated as a branch of the biological sciences, an overall approach quite different from the traditional view of caregiving in Asian societies. Nonetheless, recent research and clinical practice indicates that an indigenized form of nursing care may be a more suitable approach to comprehensive care, and that such an approach has much potential for widespread application in

  15. ELSI Bibliography: Ethical legal and social implications of the Human Genome Project

    Energy Technology Data Exchange (ETDEWEB)

    Yesley, M.S. [comp.

    1993-11-01

    This second edition of the ELSI Bibliography provides a current and comprehensive resource for identifying publications on the major topics related to the ethical, legal and social issues (ELSI) of the Human Genome Project. Since the first edition of the ELSI Bibliography was printed last year, new publications and earlier ones identified by additional searching have doubled our computer database of ELSI publications to over 5600 entries. The second edition of the ELSI Bibliography reflects this growth of the underlying computer database. Researchers should note that an extensive collection of publications in the database is available for public use at the General Law Library of Los Alamos National Laboratory (LANL).

  16. Mapping and sequencing the human genome: Science, ethics, and public policy. Final report

    Energy Technology Data Exchange (ETDEWEB)

    McInerney, J.D.

    1993-03-31

    Development of Mapping and Sequencing the Human Genome: Science, Ethics, and Public Policy followed the standard process of curriculum development at the Biological Sciences Curriculum Study (BSCS), the process is described. The production of this module was a collaborative effort between BSCS and the American Medical Association (AMA). Appendix A contains a copy of the module. Copies of reports sent to the Department of Energy (DOE) during the development process are contained in Appendix B; all reports should be on file at DOE. Appendix B also contains copies of status reports submitted to the BSCS Board of Directors.

  17. Consensus standards for introductory e-learning courses in human participants research ethics.

    Science.gov (United States)

    Williams, John R; Sprumont, Dominique; Hirtle, Marie; Adebamowo, Clement; Braunschweiger, Paul; Bull, Susan; Burri, Christian; Czarkowski, Marek; Fan, Chien Te; Franck, Caroline; Gefenas, Eugenjius; Geissbuhler, Antoine; Klingmann, Ingrid; Kouyaté, Bocar; Kraehenbhul, Jean-Pierre; Kruger, Mariana; Moodley, Keymanthri; Ntoumi, Francine; Nyirenda, Thomas; Pym, Alexander; Silverman, Henry; Tenorio, Sara

    2014-06-01

    This paper reports the results of a workshop held in January 2013 to begin the process of establishing standards for e-learning programmes in the ethics of research involving human participants that could serve as the basis of their evaluation by individuals and groups who want to use, recommend or accredit such programmes. The standards that were drafted at the workshop cover the following topics: designer/provider qualifications, learning goals, learning objectives, content, methods, assessment of participants and assessment of the course. The authors invite comments on the draft standards and eventual endorsement of a final version by all stakeholders.

  18. [Influence of the Nuremberg physicians' trials--beginning a new era in the ethical judging of human experiments].

    Science.gov (United States)

    Kerpel-Fronius, Sándor

    2008-02-03

    This short historical review attempts to shed light on the tortuous road on which society moved toward the general acceptance of the idea of experimenting on human beings. Unfortunately people had to realize that under antihuman or lenient political leadership, some physicians might apply their knowledge against their fellow beings, or might endanger them while pursuing their scientific goals. For this reason, it became necessary to codify the ethical requirements of medical experiments. This was done first by the Prussian government in 1900. The historical significance of the Nuremberg physicians' trials is that, by recognizing the enormous scientific importance of human experiments, they led to the formulation of general ethical principles governing human studies, which became known as the Nuremberg Code. Broad, international regulations were developed as the consequence of the trial. Unfortunately human experiments performed on prison inmates were judged at the trial as ethically acceptable, provided an informed consent was signed. Misusing this possibility many unethical experiments were done primarily in the US after the war. The great indignation due to ethical misconduct in prison trials and the highly unethical Tuskegee experiments performed on black Americans' suffering from syphilis, led much later to the organization of independent ethics committees. Through these committees, society exercises supervision of human trials. However, in case of severely ill patients the physician might be left alone to make a quick, and ethically correct, decision corresponding to the situation. In the final analysis the safety and ethical protection of research subjects remain the joint responsibility of society and of the experimenting physicians.

  19. Extracellular calcium sensing receptor in human pancreatic cells

    Science.gov (United States)

    Rácz, G Z; Kittel, Á; Riccardi, D; Case, R M; Elliott, A C; Varga, G

    2002-01-01

    Background and aims: The extracellular calcium sensing receptor (CaR) plays a key role in the calcium homeostatic system and is therefore widely expressed in tissues involved in calcium metabolism. However, the CaR has also been identified in other tissues where its role is less clear. We have investigated the presence of the CaR in the human pancreas. Methods: Messenger RNA for the CaR was detected by reverse transcription-polymerase chain reaction and the protein was localised by immunostaining. CaR function was assayed in Capan-1 cells by measuring intracellular calcium and [3H] thymidine incorporation. Results: The receptor was highly expressed in human pancreatic ducts. It was also expressed in exocrine acinar cells, in islets of Langerhans, and in intrapancreatic nerves and blood vessels. The CaR was expressed in both normal and neoplastic human tissue samples but was detected in only one of five ductal adenocarcinoma cells lines examined. Experiments on the CaR expressing adenocarcinoma cell line Capan-1 showed that the CaR was functional and was linked to mobilisation of intracellular calcium. Stimulation of the CaR reduced Capan-1 cell proliferation. Conclusions: We propose that the CaR may play multiple functional roles in the human pancreas. In particular, the CaR on the duct luminal membrane may monitor and regulate the Ca2+ concentration in pancreatic juice by triggering ductal electrolyte and fluid secretion. This could help to prevent precipitation of calcium salts in the duct lumen. The CaR may also help to regulate the proliferation of pancreatic ductal cells. PMID:12377811

  20. In Search of Ecological Ethics

    Directory of Open Access Journals (Sweden)

    Catarina Jahnel de Oliveira

    2013-12-01

    Full Text Available In the scope of social science, studies dealing with environmental issues have gained prominence in recent years. Given the intense and profound changes the capitalist system has brought to society, culmina ng in the current environmental crisis, science and philosophy have sought ways to overcome the contradic s found in our current ethical model. In this sense, the objetive of this paper is, from a review of the related literature, to present ecological ethics as an alternative that points the way to the formula of strategies aimed at sustainability, since this ethical discourse, broaching issues such as anthropocentrism and moral competence, leads to a redefinition of the relationship between humans and their environment

  1. Ethical leadership.

    Science.gov (United States)

    Keselman, David

    2012-01-01

    In today's climate and environment, the conventional relationship between caring, economic, and administrative practices no longer serves the interest of patients, clinicians, or systems. A shift toward human caring values and an ethic of authentic healing relationships is required as systems now have to value human resources and life purposes, inner meaning, and processes for providers and patients alike. The costs of unethical behavior can be even greater for followers. When we assume the benefits of leadership, we also assume ethical burdens. It is the assertion and experience of the author that the triangle of ethics and ethical behavior, followers, and patient's outcomes are closely interrelated and affect each other in a very intimate and direct way. Unethical leadership may lead to follower disappointment and distrust, leading to lack of interest and commitment, consequently negatively impacting patient outcomes and organizational effectiveness.

  2. Integrating Public Health and Deliberative Public Bioethics: Lessons from the Human Genome Project Ethical, Legal, and Social Implications Program.

    Science.gov (United States)

    Meagher, Karen M; Lee, Lisa M

    2016-01-01

    Public health policy works best when grounded in firm public health standards of evidence and widely shared social values. In this article, we argue for incorporating a specific method of ethical deliberation--deliberative public bioethics--into public health. We describe how deliberative public bioethics is a method of engagement that can be helpful in public health. Although medical, research, and public health ethics can be considered some of what bioethics addresses, deliberative public bioethics offers both a how and where. Using the Human Genome Project Ethical, Legal, and Social Implications program as an example of effective incorporation of deliberative processes to integrate ethics into public health policy, we examine how deliberative public bioethics can integrate both public health and bioethics perspectives into three areas of public health practice: research, education, and health policy. We then offer recommendations for future collaborations that integrate deliberative methods into public health policy and practice.

  3. Overall Assessment of Human Research and Ethics Committees in the United Arab Emirates.

    Science.gov (United States)

    Abdulrahman, Mahera; Nair, Satish Chandrasekhar

    2017-04-01

    Growing demand for human health research in the United Arab Emirates (UAE) has prompted the need to develop a robust research ethics oversight. Examination of the structure, function, and practices of the human research ethics committees (HRECs), followed by evaluation of standards for measuring research output, was conducted. Results indicate that among the HRECs, 90% followed International Council for Harmonization-Good Clinical Practice guidelines, 66.6% have been in operation for more than 5 years, 95% reviewed proposals within 8 weeks, and 56% reviewed for scientific merit apart from ethics. However, systems to recognize accomplishments of researchers, funding transparency, and adverse event reporting were deployed in less than 30% of all HRECs. Research was incorporated into the vision and mission statements of many (65%) organizations. Research publications, collaborations, and recognitions were used to measure research output and report key performance indicators. In spite, resources to generate research output such as dedicated budget (20%), support staff (20%), and continuous training and mentoring program for medical residents (15%) and HREC members (25%) were somehow lacking. HREC structure and operations in the UAE are similar to other regions of the world. Systems to conduct research and report outcomes are defined in the UAE. Regulatory legislation and allocation of resources to support the clinical research enterprise will not only help to meet growing demand for clinical trials but also transform the quality of patient care in the UAE. It is anticipated that the results of this study will benefit investigators, regulators, pharmaceutical sponsors, and the policy makers in the region.

  4. Sense of presence and anxiety during virtual social interactions between a human and virtual humans

    Science.gov (United States)

    Brinkman, Willem-Paul; Hartanto, Dwi; Emmelkamp, Paul M.G.

    2014-01-01

    Virtual reality exposure therapy (VRET) has been shown to be effective in treatment of anxiety disorders. Yet, there is lack of research on the extent to which interaction between the individual and virtual humans can be successfully implanted to increase levels of anxiety for therapeutic purposes. This proof-of-concept pilot study aimed at examining levels of the sense of presence and anxiety during exposure to virtual environments involving social interaction with virtual humans and using different virtual reality displays. A non-clinical sample of 38 participants was randomly assigned to either a head-mounted display (HMD) with motion tracker and sterescopic view condition or a one-screen projection-based virtual reality display condition. Participants in both conditions engaged in free speech dialogues with virtual humans controlled by research assistants. It was hypothesized that exposure to virtual social interactions will elicit moderate levels of sense of presence and anxiety in both groups. Further it was expected that participants in the HMD condition will report higher scores of sense of presence and anxiety than participants in the one-screen projection-based display condition. Results revealed that in both conditions virtual social interactions were associated with moderate levels of sense of presence and anxiety. Additionally, participants in the HMD condition reported significantly higher levels of presence than those in the one-screen projection-based display condition (p = .001). However, contrary to the expectations neither the average level of anxiety nor the highest level of anxiety during exposure to social virtual environments differed between the groups (p = .97 and p = .75, respectively). The findings suggest that virtual social interactions can be successfully applied in VRET to enhance sense of presence and anxiety. Furthermore, our results indicate that one-screen projection-based displays can successfully activate levels of anxiety in

  5. Ethical consideration of experimentation using living human embryos: the Catholic Church's position on human embryonic stem cell research and human cloning.

    Science.gov (United States)

    Ohara, N

    2003-01-01

    Although the potential applications of human embryonic stem cells and therapeutic cloning hold promise for the alleged medical benefits, these technologies have posed profound ethical issues because they necessitate the destruction of human embryos. A fundamental point in the issues is the concept of the moral status of human embryos. The Catholic Church has held that human life begins at the moment of conception and therefore, has defended the dignity, inviolable right to life and integrity of human embryos. The Catholic Church has opposed human embryonic stem cell research and any kind of human cloning because they are contrary to the dignity of procreation, of conjugal union and of human embryos. Moreover, these techniques have the risk of creating a sub-category of human beings that are destined basically for the convenience of others. In conclusion, science and technology can never be independent of the criterion of morality, since technology exists for man and must respect his finality.

  6. Legal and ethical standards for protecting women's human rights and the practice of conscientious objection in reproductive healthcare settings.

    Science.gov (United States)

    Zampas, Christina

    2013-12-01

    The practice of conscientious objection by healthcare workers is growing across the globe. It is most common in reproductive healthcare settings because of the religious or moral values placed on beliefs as to when life begins. It is often invoked in the context of abortion and contraceptive services, including the provision of information related to such services. Few states adequately regulate the practice, leading to denial of access to lawful reproductive healthcare services and violations of fundamental human rights. International ethical, health, and human rights standards have recently attempted to address these challenges by harmonizing the practice of conscientious objection with women's right to sexual and reproductive health services. FIGO ethical standards have had an important role in influencing human rights development in this area. They consider regulation of the unfettered use of conscientious objection essential to the realization of sexual and reproductive rights. Under international human rights law, states have a positive obligation to act in this regard. While ethical and human rights standards regarding this issue are growing, they do not yet exhaustively cover all the situations in which women's health and human rights are in jeopardy because of the practice. The present article sets forth existing ethical and human rights standards on the issue and illustrates the need for further development and clarity on balancing these rights and interests. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  7. Does post-humanism still need ethics? The normativity of an open nature.

    Science.gov (United States)

    Murillo, José Ignacio

    2014-01-01

    In the current era, post-humanism usually adopts two forms. One of these is related to postmodern thought and its critique of Enlightenment ideals, while the other, which is usually referred to as transhumanism, declares itself the heir to optimistic belief in the technological progress of modernity. Nevertheless, both seem like new versions of the struggle between an individualist version of liberalism and its critics. In so far as they are ethical proposals, we may hold them to account for the vagueness of their moral objectives, which only seem to advocate - each in its own way - emancipation and the removal of barriers that may impede an increase in power. This defect is not, though, independent of their rejection of the notion of nature. By contrast, classical ethics does not focus so much on power or emancipation as on the nature of human telos and of his true growth, and it is only from this standpoint that it concerns itself with the means by which this can be achieved.

  8. Human cloning and embryo research: the 2003 John J. Conley Lecture on medical ethics.

    Science.gov (United States)

    George, Robert P

    2004-01-01

    The author, a member of the U.S. President's Council on Bioethics, discusses ethical issues raised by human cloning, whether for purposes of bringing babies to birth or for research purposes. He first argues that every cloned human embryo is a new, distinct, and enduring organism, belonging to the species Homo sapiens, and directing its own development toward maturity. He then distinguishes between two types of capacities belonging to individual organisms belonging to this species, an immediately exerciseable capacity and a basic natural capacity that develops over time. He argues that it is the second type of capacity that is the ground for full moral respect, and that this capacity (and its concomitant degree of respect) belongs to cloned human embryos no less than to adult human beings. He then considers and rejects counter-arguments to his position, including the suggestion that the capacity of embryos is equivalent to the capacity of somatic cells, that full human rights are afforded only to human organisms with functioning brains, that the possibility of twinning diminishes the moral status of embryos, that the fact that people do not typically mourn the loss of early embryos implies that they have a diminished moral status, that the fact that early spontaneous abortions occur frequently diminishes the moral status of embryos, and that his arguments depend upon a concept of ensoulment. He concludes that if the moral status of cloned human embryos is equivalent to that of adults, then public policy should be based upon this assumption.

  9. IS ETHICAL HACKING ETHICAL?

    Directory of Open Access Journals (Sweden)

    MUHAMMAD NUMAN ALI KHAN

    2011-05-01

    Full Text Available This paper explores the ethics behind ethical hacking and whether there are problems that lie with this new field of work. Since ethical hacking has been a controversial subject over the past few years, the question remains of the true intentions of ethical hackers. The paper also looks at ways in which future research could be looked intoto help keep ethical hacking, ethical.

  10. Differences in Moral Judgment on Animal and Human Ethics Issues between University Students in Animal-Related, Human Medical and Arts Programs

    OpenAIRE

    Verrinder, Joy M.; Remo Ostini; Phillips, Clive J. C.

    2016-01-01

    Moral judgment in relation to animal ethics issues has rarely been investigated. Among the research that has been conducted, studies of veterinary students have shown greater use of reasoning based on universal principles for animal than human ethics issues. This study aimed to identify if this was unique to students of veterinary and other animal-related professions. The moral reasoning of first year students of veterinary medicine, veterinary technology, and production animal science was co...

  11. Ethical issues in cloning.

    Science.gov (United States)

    Satris, S

    2000-01-01

    There is great public concern with the ethics of human cloning. This paper briefly examines some of what I identify as pseudo-problems or myths associated with cloning, and some of the more substantial ethical concerns.

  12. Research on ethics in two large Human Biomonitoring projects ECNIS and NewGeneris: a bottom up approach

    Directory of Open Access Journals (Sweden)

    Casteleyn Ludwine

    2008-01-01

    Full Text Available Abstract Assessment of ethical aspects and authorization by ethics committees have become a major constraint for health research including human subjects. Ethical reference values often are extrapolated from clinical settings, where emphasis lies on decisional autonomy and protection of individual's privacy. The question rises if this set of values used in clinical research can be considered as relevant references for HBM research, which is at the basis of public health surveillance. Current and future research activities using human biomarkers are facing new challenges and expectancies on sensitive socio-ethical issues. Reflection is needed on the necessity to balance individual rights against public interest. In addition, many HBM research programs require international collaboration. Domestic legislation is not always easily applicable in international projects. Also, there seem to be considerable inconsistencies in ethical assessments of similar research activities between different countries and even within one country. All this is causing delay and putting the researcher in situations in which it is unclear how to act in accordance with necessary legal requirements. Therefore, analysis of ethical practices and their consequences for HBM research is needed. This analysis will be performed by a bottom-up approach, based on a methodology for comparative analysis of determinants in ethical reasoning, allowing taking into account different social, cultural, political and historical traditions, in view of safeguarding common EU values. Based on information collected in real life complexity, paradigm cases and virtual case scenarios will be developed and discussed with relevant stakeholders to openly discuss possible obstacles and to identify options for improvement in regulation. The material collected will allow developing an ethical framework which may constitute the basis for a more harmonized and consistent socio-ethical and legal approach

  13. [Self-reflection, interpersonal behavior and psychoanalytic ethics].

    Science.gov (United States)

    Bürgy, M

    1997-05-01

    In the middle ages, ethical practice included a metaphysical theory of value. In comparison with that, self-reflection and interpersonality should be described as principles of more individual ethics and proceeding from philosophy to psychoanalysis in modern times. Drawing a borderline between human philosophy and metaphysies, Kant defined his so-called categorial imperative as a basic phenomenon of human reciprocity. Ethical relationship to another person, however, requires realization of one's own self, i.e. self-reflection. Hegel's subsequent association of intersubjectivity and selfreflection supplied the basis for Sarte's constitution of consciousness: Existence as existing for the good of the fellow-being. Self-reflection, basing on the sight of one's own self by the other person, leads to Sartre's concept of existential psychoanalysis and to his understanding of ethics. His concept illustrates the decline of significance of philosophy for the analysis of human relationship. Habermas describes self-reflection and interpersonality as fundamental principles of the psychoanalytic therapy and its ethical demands. With the historical concept of the super-ego, Freud established therapeutical one-sidedness and abstinence from ethics; however, as therapeutical interrelationship continued to intensity, ethics of depth psychology also began to develop. This ethical demand was not expressly formulated within the context of psychoanalysis, with the exception of jung and his epigones. Nevertheless, psychoanalytic interaction implies the development of self-reflection, which definitely represents a step forward in the sense of "ethical enlightenment" represented by Kant.

  14. Ethical issues in the translation of social neuroscience: a policy analysis of current guidelines for public dialogue in human research.

    Science.gov (United States)

    Zimmerman, Emma; Racine, Eric

    2012-01-01

    Social neuroscience and its potential implications create an interesting case study for examining human research ethics policies on the topic of public communication of research. We reviewed mainstream national and international human research ethics guidelines and policies on issues of public communication of research. Our analysis relied on five thematic nets to capture the interactions between research and the public: public understanding, knowledge translation, public participation, social outcomes, and dual use. Coverage of these topics is sparse and inconsistent in mainstream policies and guidelines. We identify three options to address these gaps and analyze their strengths and weaknesses.

  15. Legal, ethical, and human rights considerations for physicians treating children with atypical or ambiguous genitalia.

    Science.gov (United States)

    Greenberg, Julie A

    2017-06-01

    Some governments, human rights organizations, intersex organizations, and doctors have called for a moratorium on genital and gonadal surgeries for infants born with atypical or ambiguous genitalia. Moratorium supporters believe that the surgeries carry physical and emotional risks, the psychosocial benefits of these procedures have not been proven, and the surgeries violate the patients׳ fundamental human rights if they are performed before these patients can provide informed consent. Given these calls for a moratorium, treatment teams must determine how to treat their patients and how to counsel their patients׳ parents. This article examines the treatment teams׳ ethical and legal responsibilities and provides advice for treatment teams to follow that will protect their patients and their practices. Copyright © 2017. Published by Elsevier Inc.

  16. Medicine--the art of humaneness: on ethics of traditional Chinese medicine.

    Science.gov (United States)

    Qiu, R Z

    1988-08-01

    This essay discusses the ethics of traditional Chinese medicine. After a brief remark on the history of traditional Chinese medical ethics, the author outlines the Confucian ethics which formed the cultural context in which traditional Chinese medicine was evolving and constituted the core of its ethics. Then he argued that how Chinese physicians applied the principles of Confucian ethics in medicine and prescribed the attitude a physician should take to himself, to patients and to his colleagues. In the last part of the essay he discusses the characteristics of traditional Chinese medical ethics.

  17. The discursive production of professionals about humanizing health: singularity, rights and ethics1

    Science.gov (United States)

    Silva, Rose Mary Costa Rosa Andrade; de Oliveira, Denize Cristina; Pereira, Eliane Ramos

    2015-01-01

    Objective: to describe the discursive production of professionals about the humanization of health. Method: qualitative study of descriptive approach, inspired by the social representation theory, with 24 professionals in the healthcare field, working in a university hospital with the established humanization policy. The selection of participants was conducted according to criteria of adequacy and diversity for an intentional sample. Data collection was conducted by semi-structured interviews. Results: through content analysis, three categories emerged, around which the analyses were conducted: "humanizing health as an act of accepting the other as unique", "humanizing health as a matter of right" and "humanizing health as an ethical issue". The discursive production of professionals is based on a perspective which is based on the humanist prospect with socio-historical bias. Conclusion: healthcare professionals must know the National Humanization Policy in order to provide quality care, promoting the meeting, welcoming and recognition of oneself, others and their profession in the political and socio-historical scenario of their country as a citizen, not only of rights, but also of obligations. PMID:26487145

  18. The discursive production of professionals about humanizing health: singularity, rights and ethics.

    Science.gov (United States)

    Silva, Rose Mary Costa Rosa Andrade; de Oliveira, Denize Cristina; Pereira, Eliane Ramos

    2015-01-01

    to describe the discursive production of professionals about the humanization of health. qualitative study of descriptive approach, inspired by the social representation theory, with 24 professionals in the healthcare field, working in a university hospital with the established humanization policy. The selection of participants was conducted according to criteria of adequacy and diversity for an intentional sample. Data collection was conducted by semi-structured interviews. through content analysis, three categories emerged, around which the analyses were conducted: "humanizing health as an act of accepting the other as unique", "humanizing health as a matter of right" and "humanizing health as an ethical issue". The discursive production of professionals is based on a perspective which is based on the humanist prospect with socio-historical bias. healthcare professionals must know the National Humanization Policy in order to provide quality care, promoting the meeting, welcoming and recognition of oneself, others and their profession in the political and socio-historical scenario of their country as a citizen, not only of rights, but also of obligations.

  19. Ethics and data protection in human biomarker studies in environmental health.

    Science.gov (United States)

    Casteleyn, Ludwine; Dumez, Birgit; Van Damme, Karel; Anwar, Wagida A

    2013-08-01

    Human biomarker studies in environmental health are essential tools to study the relationship between health and environment. They should ultimately contribute to a better understanding of environmentally induced adverse health effects and to appropriate preventive actions. To ensure the protection of the rights and dignity of study participants a complex legal and ethical framework is applied, consisting of several international directives, conventions, and guidelines, whether or not translated in domestic laws. Main characteristics of ethics and data protection in studies using biomarkers in the field of environmental health are summarized and current discussions on related questions and bottlenecks highlighted. In the current regulatory context, dominated by the protection of the individual study participant, difficulties are reported due to the different interpretation and implementation of the regulations of concern within and across borders. Advancement of consistency and compatibility is recommended and efforts are ongoing. An increasing demand for secondary use of data and samples poses additional challenges in finding a right balance between the individual rights of the study participants on the one hand and the common interest of, and potential benefit for the public or community at large on the other. Ethics committees could play a key role in assessing problems originating from the sometimes competing needs at individual and societal level. Building trust in science amongst (potential) study participants and within the community allows the inclusion of arguments from the societal perspective. This requires increased attention for respectful communication efforts. Striving for public participation in decision making processes may promote policy relevant research and the related translation of study results into action.

  20. The ethics of human condition in the age of technological civilization. Back and forth with Heidegger and Jonas.

    Directory of Open Access Journals (Sweden)

    Angela Luzia Miranda

    2009-07-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE The ethical dimension of the human condition in our times takes increasingly more space in current philosophical discussions. In this context, the ethical principle of responsibility has been widely discussed, particularly by authors who work on the ethical implications of modern technology. In his essay on ethics for the technological age, Hans Jonas proposes to base ethics on a principle of responsibility, taking into account that we live in the age of technological civilization. The present paper explores the origins and sources of Jonas’ principle of responsibility, focusing on the influence of his teacher Martin Heidegger on Jonas’s work. The paper analyses the intrinsic and intriguing relationship between Heidegger’s ontological concept of “care” [Sorge] and the idea or responsibility in Jonas, and it examines further the current discussion on the possibility of an ethical foundation for the techno scientific civilization. Keywords:  Philosophy of technology; Éthics and technology; Ontology; Martin Heidegger; Hans Jonas.

  1. Reframing the ethical issues in part-human animal research: the unbearable ontology of inexorable moral confusion.

    Science.gov (United States)

    Haber, Matthew H; Benham, Bryan

    2012-01-01

    Research that involves the creation of animals with human-derived parts opens the door to potentially valuable scientific and therapeutic advances, yet invokes unsettling moral questions. Critics and champions alike stand to gain from clear identification and careful consideration of the strongest ethical objections to this research. A prevailing objection argues that crossing the human/nonhuman species boundary introduces inexorable moral confusion (IMC) that warrants a restriction to this research on precautionary grounds. Though this objection may capture the intuitions of many who find this research unsettling, it relies on mistaken views of both biology and moral standing, ultimately distorting the morally relevant facts. We critically examine IMC, identify mistaken essentialist assumptions, and reframe ethical concerns. The upshot is a stronger line of objection that encourages a more inclusive and productive ethical discourse.

  2. [Clinical research XXIV. From clinical judgment to ethics in research on humans].

    Science.gov (United States)

    Pérez-Rodríguez, Marcela; Palacios-Cruz, Lino; Rivas-Ruiz, Rodolfo; Talavera, Juan O

    2014-01-01

    Bioethics in research is an essential part of the structured review process of an article and it is based on three fundamental principles: respect for persons, beneficence and justice. In addition to not providing valid knowledge, a research with inadequate design, execution and statistical analysis is not ethical either, since these methodological deficiencies will produce information that will not be useful and, therefore, the risks that the participants were exposed to will have been in vain. Beyond scientific validity, there are other aspects that outline if an investigation is ethical, such as the clinical and social value of a study, a fair selection of participants, favorable risk-benefit balance, an independent review, the informed consent and respect for participants and potential participants. Throughout the article here presented, the documents that profile the behavior of investigators to protect the participants, such as the Declaration of Helsinki, the national regulations that rule us and the differences between research without risk, with minimal risk and with greater than minimal risk are discussed. That like in daily life, behavior in research involving human participants must be self-regulated, ie, people with knowledge of the existence of the law discover that the man is outside the realm of nature where work is done under the necessity of natural causality, and falls within the scope of the will; only if the man is free to decide their actions may be a law regulating their action.

  3. Ethics, the law, and prisoners: protecting society, changing human behavior, and protecting human rights.

    Science.gov (United States)

    Trestman, Robert L

    2014-09-01

    Restricting a person's liberty presents society with many inherent ethical challenges. The historical purposes of confinement have included punishment, penitence, containment, rehabilitation, and habilitation. While the purposes are indeed complex, multifaceted, and at times ambiguous or contradictory, the fact of incarceration intrinsically creates many ethical challenges for psychiatrists working in correctional settings. Role definition of a psychiatrist may be ambiguous, with potential tensions between forensic and therapeutic demands. Privacy may be limited or absent and confidentiality may be compromised. Patient autonomy may be threatened to address real or perceived security concerns. Care delivery may actually have harmful consequences in court cases for pretrial detainees or lethal consequences for those under a death sentence. An absence of data and targeted research hampers the development of evidence-based care delivery for the disenfranchised, understudied, and disproportionately ill prisoner population. In this review paper, I discuss a few of the challenges and dilemmas routinely faced and present a series of questions. Where feasible, proposed resolutions are offered.

  4. Reparations for environmental degradation and species extinction: a moral and ethical imperative for human society

    Directory of Open Access Journals (Sweden)

    John Cairns Jr.

    2003-05-01

    Full Text Available While the history of reparations within Homo sapiens is lengthy, only recently has the concept been applied to events that have caused degradation or damage to natural systems. Some effects have been unmistakable, even to the untrained eye, and reparations have been made in a short temporal span. However, what should be done about ecological damage that has occurred incrementally over large temporal or spatial spans? If all parties involved are no longer living (e.g. slavery, colonialism, should the descendants of one group, who had nothing to do with the situation and are individually innocent, pay descendants of the other, who did not suffer directly? Degradation of the planet's ecological life support system will cause all humans to suffer, directly or indirectly, regardless of the degree to which they contributed to the damage. Repair of ecological damage is an act of enlightened self-interest, as well as an ethical imperative. Although current events may make restoring the planet's ecological life support system seem futile, even irrational, the forces of destruction cannot exceed those of restoration for a substantial period of time without resulting in severe disequilibrium, whether societal or ecological. The only long-term hope for the human species - sustainability - is a constructive, compassionate approach. Regardless of what happens to humankind, it is probably that some species will survive until the sun fails. Even if the human species does not, it seems ethical to make an exit that is notable for acts of compassion rather than acts of rage and revenge.

  5. Revisiting eco-ethics and econ-ethics

    Directory of Open Access Journals (Sweden)

    Otto Kinne

    2002-11-01

    Full Text Available Modern humanity can survive only if traditional ethics are extended to include eco-ethics and econ-ethics. Success or failure in developing and implementing these new ethical constructs will affect the fate of our species Homo sapiens and that of millions of other forms of life. In the long run failure to accept and apply eco-ethics and econ-ethics would reduce the capacities of Planet Earth to support life.

  6. Narrative ethics for narrative care.

    Science.gov (United States)

    Baldwin, Clive

    2015-08-01

    Narrative permeates health care--from patients' stories taken as medical histories to the development of health policy. The narrative approach to health care has involved the move from narratives in health care as objects of study to the lens through which health care is studied and, more recently, to narrative as a form of care. In this paper, I argue that narrative care requires a move in the field of ethics--from a position where narratives are used to inform ethical decision making to one in which narrative is the form and process of ethical decision making. In other words, I argue for a narrative ethics for narrative care. The argument is relatively straightforward. If, as I argue, humans are narrative beings who make sense of themselves, others, and the world in and through narrative, we need to see our actions as both narratively based and narratively contextual and thus understanding the nature, form, and content of the narratives of which we are a part, and the process of narrativity, provides an intersubjective basis for ethical action.

  7. [Medical ethics in residency training].

    Science.gov (United States)

    Civaner, Murat; Sarikaya, Ozlem; Balcioğlu, Harun

    2009-04-01

    Medical ethics education in residency training is one of the hot topics of continuous medical education debates. Its importance and necessity is constantly stressed in declarations and statements on national and international level. Parallel to the major structural changes in the organization and the finance model of health care system, patient-physician relationship, identity of physicianship, social perception and status of profession are changing. Besides, scientific developments and technological advancements create possibilities that never exists before, and bring new ethical dilemmas along with. To be able to transplant human organs has created two major problems for instance; procurement of organs in sufficient numbers, and allocating them to the patients in need by using some prioritizing criteria. All those new and challenging questions force the health care workers to find authentic and justifiable solutions while keeping the basic professional values. In that sense, proper medical ethics education in undergraduate and postgraduate term that would make physician-to-be's and student-physicians acquire the core professional values and skill to notice, analyze and develop justifiable solutions to ethical problems is paramount. This article aims to express the importance of medical ethics education in residency training, and to propose major topics and educational methods to be implemented into. To this aim, first, undergraduate medical education, physician's working conditions, the exam of selection for residency training, and educational environment were revised, and then, some topics and educational methods, which are oriented to educate physicians regarding the professional values that they should have, were proposed.

  8. [The ethics of principles and ethics of responsibility].

    Science.gov (United States)

    Cembrani, Fabio

    2016-01-01

    In his brief comment, the author speculates if ethics in health-care relationship it still has a practical sense.The essay points out the difference between principles ethics and ethics of responsibility, supporting the latter and try to highlight its constitutive dimensions.

  9. Legal and Ethical Implications of Using Social Media in Human Resource Management

    Directory of Open Access Journals (Sweden)

    Lu Zhang

    2014-06-01

    Full Text Available Now more than ever we live in a society saturated with technology and media.  We are captured by the technology whirlwind such as the internet, instant messages, emails, and social media such as Twitter and Facebook.  Technologies not only are changing the way people live, work, and interact with each other but also the way companies conduct their businesses.  Social media no doubt is one of such technologies that enables companies to market their products and services in new and unique dimensions.  Beyond marketing, social media is also changing the way human resource professionals recruit and select employees.   Recruiting and selecting potential new employees using social media, is gaining popularity.  There are even software programs that capitalize on the information available on social media sites to assist human resources professionals to source, screen, and track job applicants.  Although there are many advantages in using social media networks to assist HR to select and filter job candidates, there are reasons for concerns.  In this paper, we’ll examine the legal and ethical consequences of using social media in the area of human resource management.   Keywords: Social Media, Facebook, Human Resources, Management.

  10. Human guinea pigs and the ethics of experimentation: the BMJ's correspondent at the Nuremberg medical trial.

    Science.gov (United States)

    Weindling, P

    1996-12-07

    Though the Nuremberg medical trial was a United States military tribunal, British forensic pathologists supplied extensive evidence for the trial. The BMJ had a correspondent at the trial, and he endorsed a utilitarian legitimation of clinical experiments, justifying the medical research carried out under Nazism as of long term scientific benefit despite the human costs. The British supported an international medical commission to evaluate the ethics and scientific quality of German research. Medical opinions differed over whether German medical atrocities should be given publicity or treated in confidence. The BMJ's correspondent warned against medical researchers being taken over by a totalitarian state, and these arguments were used to oppose the NHS and any state control over medical research.

  11. Archimedean Witness: The Application of Remote Sensing as an Aid to Human Rights Prosecutions

    Science.gov (United States)

    Walker, James Robin

    The 21st century has seen a significant increase in the use of remote sensing technology in the international human rights arena for the purposes of documenting crimes against humanity. The nexus between remote sensing, human rights activism, and international criminal prosecutions sits at a significant crossroads within geographic thought, calling attention to the epistemological and geopolitical implications that stem from the "view from nowhere" afforded by satellite imagery. Therefore, this thesis is divided into three sections. The first looks at the geographical questions raised by the expansion of remote sensing use in the context of international activism. The second explores the complications inherent in the presentation of remote sensing data as evidence of war crimes. Building upon the first two, the third section is a case study in alternate forms of analysis, aimed at expanding the utility of remote sensing data in international criminal prosecutions.

  12. Sense of presence and anxiety during virtual social interactions between a human and virtual humans

    Directory of Open Access Journals (Sweden)

    Nexhmedin Morina

    2014-04-01

    Full Text Available Virtual reality exposure therapy (VRET has been shown to be effective in treatment of anxiety disorders. Yet, there is lack of research on the extent to which interaction between the individual and virtual humans can be successfully implanted to increase levels of anxiety for therapeutic purposes. This proof-of-concept pilot study aimed at examining levels of the sense of presence and anxiety during exposure to virtual environments involving social interaction with virtual humans and using different virtual reality displays. A non-clinical sample of 38 participants was randomly assigned to either a head-mounted display (HMD with motion tracker and sterescopic view condition or a one-screen projection-based virtual reality display condition. Participants in both conditions engaged in free speech dialogues with virtual humans controlled by research assistants. It was hypothesized that exposure to virtual social interactions will elicit moderate levels of sense of presence and anxiety in both groups. Further it was expected that participants in the HMD condition will report higher scores of sense of presence and anxiety than participants in the one-screen projection-based display condition. Results revealed that in both conditions virtual social interactions were associated with moderate levels of sense of presence and anxiety. Additionally, participants in the HMD condition reported significantly higher levels of presence than those in the one-screen projection-based display condition (p = .001. However, contrary to the expectations neither the average level of anxiety nor the highest level of anxiety during exposure to social virtual environments differed between the groups (p = .97 and p = .75, respectively. The findings suggest that virtual social interactions can be successfully applied in VRET to enhance sense of presence and anxiety. Furthermore, our results indicate that one-screen projection-based displays can successfully activate levels

  13. Unintended consequences of human research ethics committees: au revoir workplace studies?

    Science.gov (United States)

    Bamber, Greg J; Sappey, Jennifer

    2007-07-01

    To protect the welfare and rights of participants in research and to facilitate research that will be of benefit, as well as protect them against litigation, universities and research-funding agencies in Australia adopted the National Statement on Ethical Conduct in Research Involving Humans (NHMRC 1999). In many other countries there are similar statements. However, the ways in which such statements are often implemented by Human Research Ethics Committees (HRECs) are in conflict with an important stream of industrial sociological research. This stream seeks to deconstruct workplaces and de-layer management rhetoric to understand the realities and complexities of the social relations of production. There is a pluralist basis for much industrial sociology that challenges the unitarist view of the workplace as essentially harmonious. While views of workplaces as being conflictual and exploitative have to be tempered with an understanding of the accommodative and cooperative nature of workplace relations, there is nevertheless a general recognition of acts of resistance, as well as those of cooperation. The way in which the National Statement is typically implemented in Australia means that many HRECs require written, informed consent, which in the first instance will usually be that of management. An unintended consequence is a research focus on consensus, which is at best one-sided and at worst seriously misleading. It is unlikely that managerial consent will be granted unless there is a 'good news story' guaranteed. This article explores the ways in which HRECs may influence workplace research. The publication of the revised National Statement provides a valuable opportunity not to be missed by HRECs to implement more effective and efficient practices which would not have the unintended consequences of the earlier version. This would deserve the support of researchers in industrial sociology and other branches of the social sciences.

  14. Predicting Team Performance through Human Behavioral Sensing and Quantitative Workflow Instrumentation

    Science.gov (United States)

    2016-07-27

    Information Theory · Operations Research · Decision- Making . 1 Introduction From network operations control centers to expeditionary military...instantiation of this approach, shown in Fig. 1, and its application to the study of teams’ abilities to effectively discover data, make sense of...Predicting Team Performance Through Human Behavioral Sensing and Quantitative Workflow Instrumentation Matthew Daggett1, Kyle O’Brien1, Michael

  15. Human impact on the planet: an earth system science perspective and ethical considerations

    Science.gov (United States)

    Williams, Richard S.

    2002-01-01

    natural and human history to stop further degradation of Earth?s ecosystems and extinction of its biota? The fate of the biosphere, including humanity, depends on a reaffirmation by all humans of all cultures and religions of the global importance of a planet-wide conservation of the Earth?s biotic heritage. For the world?s religions it means elevation of stewardship of the Earth to a moral imperative and a goal of complete preservation of the Earth?s biotic inheritance, one which is based on a Do No Harm ethic.

  16. Human Science for Human Freedom? Piaget's Developmental Research and Foucault's Ethical Truth Games

    Science.gov (United States)

    Zhao, Guoping

    2012-01-01

    The construction of the modern subject and the pursuit of human freedom and autonomy, as well as the practice of human science has been pivotal in the development of modern education. But for Foucault, the subject is only the effect of discourses and power-knowledge arrangements, and modern human science is part of the very arrangement that has…

  17. Human Science for Human Freedom? Piaget's Developmental Research and Foucault's Ethical Truth Games

    Science.gov (United States)

    Zhao, Guoping

    2012-01-01

    The construction of the modern subject and the pursuit of human freedom and autonomy, as well as the practice of human science has been pivotal in the development of modern education. But for Foucault, the subject is only the effect of discourses and power-knowledge arrangements, and modern human science is part of the very arrangement that has…

  18. Engineer Ethics

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dae Sik; Kim, Yeong Pil; Kim, Yeong Jin

    2003-03-15

    This book tells of engineer ethics such as basic understanding of engineer ethics with history of engineering as a occupation, definition of engineering and specialized job and engineering, engineer ethics as professional ethics, general principles of ethics and its limitation, ethical theory and application, technique to solve the ethical problems, responsibility, safety and danger, information engineer ethics, biotechnological ethics like artificial insemination, life reproduction, gene therapy and environmental ethics.

  19. The Ethics and Politics of Ethics Approval

    Science.gov (United States)

    Battin, Tim; Riley, Dan; Avery, Alan

    2014-01-01

    The regulatory scope of Human Research Ethics Committees can be problematic for a variety of reasons. Some scholars have argued the ethics approval process, for example, is antithetical to certain disciplines in the humanities and social sciences, while others are willing to give it qualified support. This article uses a case study to cast the…

  20. [Ethical and legal principles for the activities of bioprospection in relation to human beings and the human genome].

    Science.gov (United States)

    Romeo Casabona, Carlos María

    2012-01-01

    During recent decades, bioprospecting has become an important field of research, which looks for development alternatives, entry into global (environmental) markets, and the subsequent obtention of benefits under sustainable development principles. However, there is still so much to discuss regarding the social and environmental impacts produced by this activity, as well as its main limitations. To this end, the Forum/round-table discussion, entitled "Bioprospección, Etica y Sociedad" was organised to take place on 28 March 2012 at the National University of Colombia. Its main objective was to enrich our knowledge on bioprospecting considering the ethical considerations that involve society. The presentation given by Professor ROMEO CASABONA, regarding the connection between bioprospecting and the human genome deserves special attention and is presented below.

  1. Addressing the ethical issues raised by synthetic human entities with embryo-like features

    Science.gov (United States)

    Aach, John; Lunshof, Jeantine; Iyer, Eswar; Church, George M

    2017-01-01

    The "14-day rule" for embryo research stipulates that experiments with intact human embryos must not allow them to develop beyond 14 days or the appearance of the primitive streak. However, recent experiments showing that suitably cultured human pluripotent stem cells can self-organize and recapitulate embryonic features have highlighted difficulties with the 14-day rule and led to calls for its reassessment. Here we argue that these and related experiments raise more foundational issues that cannot be fixed by adjusting the 14-day rule, because the framework underlying the rule cannot adequately describe the ways by which synthetic human entities with embryo-like features (SHEEFs) might develop morally concerning features through altered forms of development. We propose that limits on research with SHEEFs be based as directly as possible on the generation of such features, and recommend that the research and bioethics communities lead a wide-ranging inquiry aimed at mapping out solutions to the ethical problems raised by them. DOI: http://dx.doi.org/10.7554/eLife.20674.001

  2. Biomimicry: a Necessary Eco-Ethical Dimension for a Future Human Sustainability

    Directory of Open Access Journals (Sweden)

    Javier Collado-Ruano

    2015-07-01

    Full Text Available This article reflects on the concept of “global citizenship” from a transdisciplinary methodology and a biomimetic approach. A sustainable human image appears with this epistemological symbiosis, that constitutes the DNA of a genuine tool of civilizational transformation. On the one hand, the transdisciplinary methodology is opened to the multi-referential conception of the three pillars proposed by Basarab Nicolescu (2008: levels of reality, logic of the included middle, and complexity. On the other hand, the concept of biomimicry approached by Janine M. Benyus (2012 identifies nine operating principles of life in order to mimic nature in the reformulation of new sustainable human production systems with the biosphere. The aim of this study is to identify international agreements on environmental and sustainable development, to elaborate some contribution in the post-2015 eco-political-educational strategic framework led by the United Nations with the Sustainable Development Goals. With the purpose of strengthening ties between education and sustainability through symbiotic bridges between nature and culture, the work identifies the vital axises that constitute the interdependence of ecosystems to make a biomimetic application in the social, political, and educational structures of human systems. Then, this paper is an innovational research that seeks to integrate the eco-ethics as a practice in the “Global Citizenship Education” proposed for UNESCO for next decade 2015-2025.

  3. Ethics and Law

    Science.gov (United States)

    Vilacoba Ramos, Andrés

    2007-04-01

    Ethics are the set of moral rules that govern human conduct. Hegel, for his part, asserted that ethicity implied the full realization of freedom, as well as the suppression of it as arbitrariness. In this paper, we point out that, through the relation between Law and Ethics, we can discover how high are the Ethics of a society, as well as the adherence of its members to it.

  4. ETHICS AND CHANGES IN SPORT

    OpenAIRE

    Jovo Radoš; Milan Nešić

    2008-01-01

    Ethics, as a practical philosophy, is found in essential relationships and relations with other relevant practical disciplines (economics, law, politics, sport, etc.). Every human activity is ethically grounded. Therefore, human ethics, which includes sport ethics, is one of the fundamental criteria for establishing moral relations in different are as of sport life. Sport morale stems from a universally accepted ethics legal principles that aim at maintaining sport spirit based on the Olympic...

  5. Incidental findings in the use of DNA to identify human remains: an ethical assessment.

    Science.gov (United States)

    Parker, Lisa S; London, Alex John; Aronson, Jay D

    2013-02-01

    DNA analysis is increasingly used to identify the remains of victims of conflicts and disasters. This is especially true in cases where remains are badly damaged and fragmented, or where antemortem records are unavailable. Incidental findings (IFs)-that is, genetics-related information for which investigators were not looking-may result from these identification efforts employing DNA analysis. Because of the critical role played by family members of the missing in identification efforts, as well as the familial nature of DNA, identification initiatives employing DNA analysis are particularly prone to reveal IFs about familial relationships, such as misattributed paternity or false beliefs about sibling relationships. Despite forensic scientists' widespread awareness of the possibility of generating IFs, to date there has been relatively little explicit guidance about their management. This paper fills that gap. It offers substantive guidance about the ethical management of IFs in this context. To ensure that the analysis addresses actual needs and practices in the field, one author (JDA) conducted semi-structured interviews with key informants from six regionally diverse organizations involved in post-conflict or post-disaster identification efforts. The paper first describes how methods of DNA analysis give rise to IFs. Next, it explains the importance of developing an ethically justified general policy for managing IFs and discusses features of DNA identification efforts that are relevant to such a policy. Then it presents an argument in support of a general policy of nondisclosure-specifically, that considerations of fair access to the individual and social benefits of identification efforts, and the concern to minimize and fairly distribute the risks of participation, support a policy of nondisclosure. It concludes by considering some implications of this argument for the choice among scientific practices involved in using DNA analysis to identify human remains

  6. Incidental Findings in the Use of DNA to Identify Human Remains: An Ethical Assessment

    Science.gov (United States)

    Parker, Lisa S.; Aronson, Jay D.

    2012-01-01

    DNA analysis is increasingly used to identify the remains of victims of conflicts and disasters. This is especially true in cases where remains are badly damaged and fragmented, or where antemortem records are unavailable. Incidental findings (IFs)—that is, genetics-related information for which investigators were not looking—may result from these identification efforts employing DNA analysis. Because of the critical role played by family members of the missing in identification efforts, as well as the familial nature of DNA, identification initiatives employing DNA analysis are particularly prone to reveal IFs about familial relationships, such as misattributed paternity or false beliefs about sibling relationships. Despite forensic scientists’ widespread awareness of the possibility of generating IFs, to date there has been relatively little explicit guidance about their management. This paper fills that gap. It offers substantive guidance about the ethical management of IFs in this context. To ensure that the analysis addresses actual needs and practices in the field, one author (JDA) conducted semi-structured interviews with key informants from six regionally diverse organizations involved in post-conflict or post-disaster identification efforts. The paper first describes how methods of DNA analysis give rise to IFs. Next, it explains the importance of developing an ethically justified general policy for managing IFs and discusses features of DNA identification efforts that are relevant to such a policy. Then it presents an argument in support of a general policy of nondisclosure—specifically, that considerations of fair access to the individual and social benefits of identification efforts, and the concern to minimize and fairly distribute the risks of participation, support a policy of nondisclosure. It concludes by considering some implications of this argument for the choice among scientific practices involved in using DNA analysis to identify human

  7. Where are human subjects in Big Data research? The emerging ethics divide

    OpenAIRE

    Jacob Metcalf; Kate Crawford

    2016-01-01

    There are growing discontinuities between the research practices of data science and established tools of research ethics regulation. Some of the core commitments of existing research ethics regulations, such as the distinction between research and practice, cannot be cleanly exported from biomedical research to data science research. Such discontinuities have led some data science practitioners and researchers to move toward rejecting ethics regulations outright. These shifts occur at the sa...

  8. Ethics and Dualism in Contemporary Psychology: From Avicenna and Descartes to Neuroscience

    OpenAIRE

    Jeftiċ, Alma

    2014-01-01

    From Avicenna and Descartes a long debate on the role of mind-body dilemma has left a huge impact on ethics of psychological research. That is especially applicable on researches that include both human and non-human participants, as well as their limitations and constraints that are connected to ethical principles. However, these principles are closely related to the interpretation of mind-body dilemma, which depends on different understandings of connection between soul and senses. The purp...

  9. Health care ethics consultation: an update on core competencies and emerging standards from the American Society For Bioethics and Humanities' core competencies update task force.

    Science.gov (United States)

    Tarzian, Anita J

    2013-01-01

    Ethics consultation has become an integral part of the fabric of U.S. health care delivery. This article summarizes the second edition of the Core Competencies for Health Care Ethics Consultation report of the American Society for Bioethics and Humanities. The core knowledge and skills competencies identified in the first edition of Core Competencies have been adopted by various ethics consultation services and education programs, providing evidence of their endorsement as health care ethics consultation (HCEC) standards. This revised report was prompted by thinking in the field that has evolved since the original report. Patients, family members, and health care providers who encounter ethical questions or concerns that ethics consultants could help address deserve access to efficient, effective, and accountable HCEC services. All individuals providing such services should be held to the standards of competence and quality described in the revised report.

  10. Protest of doctors: a basic human right or an ethical dilemma.

    Science.gov (United States)

    Abbasi, Imran Naeem

    2014-03-10

    Peaceful protests and strikes are a basic human right as stated in the United Nations' universal declaration on human rights. But for doctors, their proximity to life and death and the social contract between a doctor and a patient are stated as the reasons why doctors are valued more than the ordinary beings. In Pakistan, strikes by doctors were carried out to protest against lack of service structure, security and low pay. This paper discusses the moral and ethical concerns pertaining to the strikes by medical doctors in the context of Pakistan. The author has carefully tried to balance the discussion about moral repercussions of strikes on patients versus the circumstances of doctors working in public sector hospitals of a developing country that may lead to strikes. Doctors are envisaged as highly respectable due to their direct link with human lives. Under Hippocrates oath, care of the patient is a contractual obligation for the doctors and is superior to all other responsibilities. From utilitarian perspective, doctors' strikes are justifiable only if there is evidence of long term benefits to the doctors, patients and an improvement in service delivery. Despite that, it is hard to justify such benefits against the risks to the patients. Harms that may incur to the patients include: prolongation of sufferings, irreversible damage to health, delay in treatment, death, loss of work and waste of financial resources.In a system of socialized medicine, government owing to greater control over resources and important managerial decisions should assume greater responsibility and do justice to all stakeholders including doctors as well as patients. If a doctor is underpaid, has limited options for career growth and is forced to work excessively, then not only quality of medical care and ability to act in the best interests of patients is adversely affected, it may also lead to brain drain. There is no single best answer against or in favor of doctors' industrial

  11. National ethics guidance in Sub-Saharan Africa on the collection and use of human biological specimens: a systematic review.

    Science.gov (United States)

    Barchi, Francis; Little, Madison T

    2016-10-22

    Ethical and regulatory guidance on the collection and use of human biospecimens (HBS) for research forms an essential component of national health systems in Sub-Saharan Africa (SSA), where rapid advances in genetic- and genomic-based technologies are fueling clinical trials involving HBS and the establishment of large-scale biobanks. An extensive multi-level search for publicly available ethics regulatory guidance was conducted for each SSA country. A second review documented active trials listed in the WHO International Clinical Trials Registry Platform as of January 2015 in which HBS collection was specified in the protocol. Findings were combined to determine the extent to which countries that are study sites for HBS-related research are supported by regulatory guidance language on the collection, use, ownership and storage of biospecimens. Of the 49 SSA countries, 29 had some form of national ethics guidance, yet only 17 provided language relating to HBS-related research, with specific guidance on consent (14), ownership (6), reuse (10), storage (9), and export/import/transfer (13). Ten countries accounted for 84 % of the active clinical trials involving the collection of HBS in SSA. All except one of these countries were found to have some national guidance in the form of regulations, codes of ethics, and/or standard operating procedures; however, only seven of the ten offered any language specific to HBS. Despite the fact that the bulk of registered clinical trials in SSA involving HBS, as well as existing and proposed sites for biorepositories under the H3Africa Initiative, are currently situated in countries with the most complete ethics and regulatory guidance, variability in the regulations themselves may create challenges for planned and future pan-African collaborations and may require legislative action at the national level to revise. Countries in SSA that still lack regulatory guidance on HBS will require extensive health system strengthening in

  12. Ethics and Economics: A Comment on Narvaez's "Revitalizing Human Virtue by Restoring Organic Morality"

    Science.gov (United States)

    Minnameier, Gerhard

    2016-01-01

    This paper comments on Darcia Narvaez's Kohlberg Memorial Lecture (EJ1111256), published in this issue, with respect to her contrasting ethics and economics, or morality and market. My basic claim is that ethics and economics, properly understood, are just two sides of the same coin. One main point is that all morality solves cooperation problems…

  13. Ethical Guidelines for Human Communication and Public Discussion: A Gandhian Intercultural Perspective.

    Science.gov (United States)

    Bode, Robert A.

    Ethical communication scholars frequently find national popular rhetoric unethical. Some proposed ethical guidelines for the public presentation of ideas call for such elements as habits of search, justice, preference for public versus private motives, respect for dissent, airing of all relevant arguments, and persuasion without coercion or…

  14. University Students and Ethics of Computer Technology Usage: Human Resource Development

    Science.gov (United States)

    Iyadat, Waleed; Iyadat, Yousef; Ashour, Rateb; Khasawneh, Samer

    2012-01-01

    The primary purpose of this study was to determine the level of students' awareness about computer technology ethics at the Hashemite University in Jordan. A total of 180 university students participated in the study by completing the questionnaire designed by the researchers, named the Computer Technology Ethics Questionnaire (CTEQ). Results…

  15. Ethics and Economics: A Comment on Narvaez's "Revitalizing Human Virtue by Restoring Organic Morality"

    Science.gov (United States)

    Minnameier, Gerhard

    2016-01-01

    This paper comments on Darcia Narvaez's Kohlberg Memorial Lecture (EJ1111256), published in this issue, with respect to her contrasting ethics and economics, or morality and market. My basic claim is that ethics and economics, properly understood, are just two sides of the same coin. One main point is that all morality solves cooperation problems…

  16. University Students and Ethics of Computer Technology Usage: Human Resource Development

    Science.gov (United States)

    Iyadat, Waleed; Iyadat, Yousef; Ashour, Rateb; Khasawneh, Samer

    2012-01-01

    The primary purpose of this study was to determine the level of students' awareness about computer technology ethics at the Hashemite University in Jordan. A total of 180 university students participated in the study by completing the questionnaire designed by the researchers, named the Computer Technology Ethics Questionnaire (CTEQ). Results…

  17. [Experience of a research Ethics Committee and the challenges of the new Chilean legislation on research in human beings].

    Science.gov (United States)

    Oyarzún G, Manuel; Pinto C, María Eugenia; Raineri B, Gina G; Amigo, Hugo; Cifuentes O, Lucía; González, María Julieta; Horwitz, Nina; Marshall F, Claudia; Orellana V, Gricel

    2014-07-01

    The welfare of research participants must be guaranteed by international ethical standards. This article communicates the procedures of the Research Ethics Committee of the School of Medicine, University of Chile (CEISH). The new Chilean legislation on research in human beings is also discussed. Law 20.120: "On scientific research in human beings, its genome and forbidding human cloning" establishes the ethical principles that must be accomplished in every research involving human beings. Article 28 of the Law 20.584 "Regulation of the rights and duties of health care users", forbids the participation of handicapped people who cannot express their will in scientific research. Article 13 states that people not related directly with patient care cannot have access to his clinical records (with the exception of people with notarial authorization by the patient). CEISH proposes that, in case of people with intellectual deficiency, the decision to approve a scientific research should be analyzed on an individual basis. If the person is capable of expressing his or her will or has stated his or her consent beforehand, the research can be authorized. If the person cannot express his or her will, the scientific research cannot take place. In prospective studies, a consent from the patient and an authorization of the health authority should be required to access clinical records. In retrospective studies, consent should be obtained from the patient when personal information is going to be used. If the information is nameless, the consent can be disregarded.

  18. Human rights from the Nuremberg Doctors Trial to the Geneva Declaration. Persons and institutions in medical ethics and history.

    Science.gov (United States)

    Frewer, Andreas

    2010-08-01

    The "Universal Declaration of Human Rights" and the "Geneva Declaration" by the World Medical Association, both in 1948, were preceded by the foundation of the United Nations in New York (1945), the World Medical Association in London (1946) and the World Health Organization in Geneva (1948). After the end of World War II the community of nations strove to achieve and sustain their primary goals of peace and security, as well as their basic premise, namely the health of human beings. All these associations were well aware of the crimes by medicine, in particular by the accused Nazi physicians at the Nuremberg Doctors Trial (1946/47, sentence: August 1947). During the first conference of the World Medical Association (September 1947) issues of medical ethics played a major role: and a new document was drafted concerning the values of the medical profession. After the catastrophe of the War and the criminal activities of scientists, the late 1940s saw increased scrutiny paid to fundamental questions of human rights and medical ethics, which are still highly relevant for today's medicine and morality. The article focuses on the development of medical ethics and human rights reflected in the statement of important persons, codes and institutions in the field.

  19. Pathogen sensing, subsequent signalling, and signalosome in human platelets.

    Science.gov (United States)

    Garraud, Olivier; Berthet, Julien; Hamzeh-Cognasse, Hind; Cognasse, Fabrice

    2011-04-01

    Beyond haemostasis, platelets exert a potent role in innate immunity and particularly in its inflammatory arm. The extent of this action remains however debatable, despite clear - and old - evidence of a link between platelets and infection. Platelets can sense infectious pathogens by pathogen recognition receptors and they can even discriminate between various types of infectious signatures. In reply, they can shape their capacity to respond by activating a signalosome and by producing different profiles of pro-inflammatory cytokines and related products. The links between pathogen sensing, signalosome activation and protein production, and their finely tuned regulation are still under investigation since platelets lack a nucleus and thus, canonical molecular biology and genomics apparati.

  20. The Council of Europe Convention on Human Rights and Biomedicine: a new look at international biomedical law and ethics.

    Science.gov (United States)

    Salako, Solomon E

    2008-06-01

    The Council of Europe Convention on Human Rights and Biomedicine is European in conception but has a wider territorial application since non-Member States which have participated in its elaboration may sign it. This article evaluates the Convention as the first legally binding international biomedical law and ethics document to uphold human dignity as a fundamental concept and to provide a legal framework for societies with different sociocultural and philosophical backgrounds. It is argued that such a legal framework must be underpinned by a monist-naturalist conception of justice privileging human dignity as one of its guiding principles.

  1. Spheres of influence: Ethical, legal, and social issues of the Human Genome Project: What to do with what we know

    Energy Technology Data Exchange (ETDEWEB)

    Pellerin, C. (Alexandria, VA (United States))

    1994-01-01

    Since fiscal year 1991, the U.S. Human Genome Project has spent $170.6 million in federal funds to help isolate genes associated with Huntington's disease, amyotrophic lateral sclerosis, neurofibromatosis types 1 and 2, myotonic dystrophy, and fragile X syndrome and to localize genes that predispose people to breast cancer, colon cancer, hypertension, diabetes, and Alzheimer's disease. Now come the hard part. Biology's 21st century megaproject starts to look relatively manageable compared to another challenge facing the enterprise: sorting out ethical, legal, and social issues associated with using this information. [open quotes]The Human Genome Project,[close quotes] wrote Senior Editor Barbara Jasny in the October 1 Science editorial, stretches [open quotes]the limits of the technology and the limits of our ability to ethically and rationally apply genetic information to our lives.[close quotes

  2. Publishing SNP genotypes of human embryonic stem cell lines: policy statement of the International Stem Cell Forum Ethics Working Party.

    Science.gov (United States)

    Knoppers, Bartha M; Isasi, Rosario; Benvenisty, Nissim; Kim, Ock-Joo; Lomax, Geoffrey; Morris, Clive; Murray, Thomas H; Lee, Eng Hin; Perry, Margery; Richardson, Genevra; Sipp, Douglas; Tanner, Klaus; Wahlström, Jan; de Wert, Guido; Zeng, Fanyi

    2011-09-01

    Novel methods and associated tools permitting individual identification in publicly accessible SNP databases have become a debatable issue. There is growing concern that current technical and ethical safeguards to protect the identities of donors could be insufficient. In the context of human embryonic stem cell research, there are no studies focusing on the probability that an hESC line donor could be identified by analyzing published SNP profiles and associated genotypic and phenotypic information. We present the International Stem Cell Forum (ISCF) Ethics Working Party's Policy Statement on "Publishing SNP Genotypes of Human Embryonic Stem Cell Lines (hESC)". The Statement prospectively addresses issues surrounding the publication of genotypic data and associated annotations of hESC lines in open access databases. It proposes a balanced approach between the goals of open science and data sharing with the respect for fundamental bioethical principles (autonomy, privacy, beneficence, justice and research merit and integrity).

  3. Toward robot ethics through the ethics of autism

    OpenAIRE

    2011-01-01

    The aim of this chapter is to present an ethical landscape for humans and autonomous robots in the future of a physicalistic world, and which will touch mainly on a framework of robot ethics rather than the concrete ethical problems possibly caused by recent robot technologies. It might be difficult to find sufficient answers to such ethical problems as those occurring with future military robots unless we understand what autonomy in autonomous robots exactly implies for robot ethics. This ch...

  4. Controlling our destinies: Historical, philosophical, social and ethical perspectives on the Human Genome Project: Final report, July 1, 1995-June 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Sloan, P.R.

    1996-09-25

    This report briefly describes the efforts by the organizing committee in preparation for the conference entitled Controlling Our Destinies: Historical, Philosophical, Social, and Ethical Perspectives on the Human Genome Project. The conference was held October 5-8, 1995.

  5. Ethical issues in the ethnography of cyberspace.

    Science.gov (United States)

    Hakken, D

    2000-01-01

    The project of developing an anticipatory anthropology of the future reveals unique ethical opportunities. For example, the increased importance of performance means there is a substantial potential for a substantive "resocialing" of work in organizations, just as the decline of Modernism opens space for collective, situated ethics as opposed to individualized categorical imperatives. An anthropology of the future should address the question of the future of ethics in general. The very possibility of human agency, of informed individual moral action, is brought into question in new ways. The profound flexibility of the computer as a medium carries with it the dangers of hyper-abstraction, while the consolidation of capital reproduction on a global level increases the scope for apparently permanent mystification. Also important are the new ethical challenges raised for those engaged in knowledge "production" or science broadly conceived. These include the necessary effort to acknowledge fully the role of non-human agency, and the potentially profound possibilities in a transformation in the character of knowledge, a correlate, at least in part, of the commodification of knowledge associated with distance learning. These challenges accompany the more overt threats of transgenic entities and ecological degradation. How can one be an ethical intellectual or academic under these circumstances, let alone teach others to be? There are also some specific challenges facing anthropology in particular. Some derive from the increasing "privatization" of ethnography, both in its growing popularity in modes of social reproduction more directly implicated in the reproduction of capital and in the declining academic support for anthropology. In a very specific sense, anthropology has grounded its ethics on an appreciation of and support for the reproduction of "really existing" culture. This ethical compass is not available to the ethnographer who studies the future. How do we

  6. Ethics in human experimentation: the two military physicians who helped develop the Nuremberg Code.

    Science.gov (United States)

    Temme, Leonard A

    2003-12-01

    The Nuremberg Code is generally considered the beginning of modern ethics in human experimentation. The Code is a list of 10 principles that Judge Walter Beals included in the judgment he delivered at the close of the Nuremberg Medical Trial on 19 August 1947. Recently, scholars have studied the origin of the Code, who wrote it, and why. This is important to military medicine and the Aerospace Medical Association in particular because many of the defendants claimed their crimes were experiments in aviation and environmental physiology conducted under wartime conditions. The chief prosecutor of the Nuremberg Medical Trial, General Telford Taylor, relied on the guidance of an advisor provided by the American Medical Association, Andrew C. Ivy, one of the foremost physiologists of his time. The neurologist, Leo Alexander, then a colonel in the U.S. Army Reserves, was another medical advisor. Both men were crucial to the development of Taylor's courtroom strategy. The material Alexander and Ivy provided was incorporated verbatim in the section of the judgment that became the Code. Although both men contributed to the Code, Ivy provided what seems to be the first formulation of many of these principles during a meeting of Allied medical investigators at the Pasteur Institute in July 1946. Naval researchers should note that Ivy had been the Director of the Research Division of the Naval Medical Research Institute when it was commissioned on October 27, 1942.

  7. ELSI Bibliography: Ethical, legal and social implications of the Human Genome Project. 1994 Supplement

    Energy Technology Data Exchange (ETDEWEB)

    Yesley, M.S.; Ossorio, P.N. [comps.

    1994-09-01

    This report updates and expands the second edition of the ELSI Bibliography, published in 1993. The Bibliography and Supplement provides a comprehensive resource for identifying publications on the major topics related to the ethical, legal and social issues (ELSI) of the Human Genome Project. The Bibliography and Supplement are extracted from a database compiled at Los Alamos National Laboratory with the support of the Office of Energy Research, US Department of Energy. The second edition of the ELSI Bibliography was dated May 1993 but included publications added to the database until fall 1993. This Supplement reflects approximately 1,000 entries added to the database during the past year, bringing the total to approximately 7,000 entries. More than half of the new entries were published in the last year, and the remainder are earlier publications not previously included in the database. Most of the new entries were published in the academic and professional literature. The remainder are press reports from newspapers of record and scientific journals. The topical listing of the second edition has been followed in the Supplement, with a few changes. The topics of Cystic Fibrosis, Huntington`s Disease, and Sickle Cell Anemia have been combined in a single topic, Disorders. Also, all the entries published in the past year are included in a new topic, Publications: September 1993--September 1994, which provides a comprehensive view of recent reporting and commentary on the science and ELSI of genetics.

  8. From human ability to ethical principle: an intercultural perspective on autonomy.

    Science.gov (United States)

    Hanssen, Ingrid

    2004-01-01

    Based on an empirical study regarding ethical challenges within intercultural health care, the focus of this article is upon autonomy and disclosure, discussed in light of philosophy and anthropology. What are the consequences for patients if the patients' right to be autonomous and to participate in treatment and care decisions by health care workers is interpreted as an obligation to participate? To force a person to make independent choices who is socio-culturally unprepared to do so, may violate his/her integrity. This may in turn jeopardise the respect, integrity and human worth the principle of autonomy was meant to ensure, and if so, may damage any relationship of trust that may exist between patient and health care worker. There is necessarily a link between autonomy and disclosure. Western disclosure practices may make the relationship between patients and health care workers difficult--even distrustful. To confront a patient with a very serious diagnosis may be seen not only as a tactless action, but also an unforgivable one. Hence, among many ethnic groups it is a family member's duty to shield patients from bad or disquieting news, e.g., a cancer diagnosis. If a family member is used to interpret in such situations, will the information given equal the information communicated by that interpreter? Even though respect for a person's autonomy is part of the respect for a person, one's respect for the person in question should not depend on his/her ability or aptitude to act autonomously.

  9. Love and caring. Ethics of face and hand--an invitation to return to the heart and soul of nursing and our deep humanity.

    Science.gov (United States)

    Watson, Jean

    2003-01-01

    This manuscript offers a new view of old and timeless values: the essential ethic of love, informed by contemporary European philosophies, and caring theory, as well as ancient poetry and wisdom traditions. It integrates some of the philosophical views of Levinas and Logstrup with Watson's Transpersonal Caring Theory. The metaphysics, metaphors, and meanings associated with "ethics of face," the "infinity of the human soul," and "holding another's life in our hands" are tied to a deeply ethical foundation for the timeless practice of love and caring, as a means to sustain, not only our shared humanity, but the profession of nursing itself.

  10. [Health policies and politicized health? An analysis of sexual and reproductive health policies in Peru from the perspective of medical ethics, quality of care, and human rights].

    Science.gov (United States)

    Miranda, J Jaime; Yamin, Alicia Ely

    2008-01-01

    Health professionals view medical ethics as a discipline that provides the basis for more adequate patient care. In recent years the concepts of quality of care and human rights - with their attending discourses - have joined the concept of medical ethics among the paradigms to consider in care for humans both at the individual and health policy levels. The current study seeks to analyze such paradigms, based on a case study of sexual and reproductive health policies in Peru in the last 10 years.

  11. [Ethical aspects of human embryonic stem cell use and commercial umbilical cord blood stem cell banking. Ethical reflections on the occasion of the regulation of the European Council and Parliament on advanced therapy medicinal products].

    Science.gov (United States)

    Virt, G

    2010-01-01

    The regulation of the European Council and Parliament on advanced therapy medicinal products also includes therapies with human embryonic stem cells. The use of these stem cells is controversially and heavily discussed. Contrary to the use of adult stem cells, medical and ethical problems concerning the use of human embryonic stem cells persists, because this use is based on the destruction of human life at the very beginning. The regulation foresees, therefore, subsidiarity within the European Member States. Although there are no ethical problems in principle with the use of stem cells from the umbilical cord blood, there are social ethical doubts with the banking of these stem cells for autologous use without any currently foreseeable medical advantage by commercial blood banks. Also in this case subsidiarity is valid.

  12. Science, humanism, judgement, ethics: person-centered medicine as an emergent model of modern clinical practice.

    Science.gov (United States)

    Miles, Andrew

    2013-01-01

    The Medical University of Plovdiv (MUP) has as its motto 'Committed to humanity". But what does humanity in modern medicine mean? Is it possible to practise a form of medicine that is without humanity? In the current article, it is argued that modern medicine is increasingly being practised in a de-personalised fashion, where the patient is understood not as a unique human individual, a person, but rather as a subject or an object and more in the manner of a complex biological machine. Medicine has, it is contended, become distracted from its duty to care, comfort and console as well as to ameliorate, attenuate and cure and that the rapid development of medicine's scientific knowledge is, paradoxically, principally causative. Signal occurrences in the 'patient as a person' movement are reviewed, together with the emergence of the evidence-based medicine (EBM) and patient-centered care (PCC) movements. The characteristics of a model of medicine evolving in response to medicine's current deficiencies--person-centered healthcare (PCH)--are noted and described. In seeking to apply science with humanism, via clinical judgement, within an ethical framework, it is contended that PCH will prove to be far more responsive to the needs of the individual patient and his/her personal circumstances than current models of practice, so that neither a reductive anatomico-pathological, disease-centric model of illness (EBM), nor an aggressive patient-directed, consumerist form of care (PCC) is allowed continued dominance within modern healthcare systems. In conclusion, it is argued that PCH will enable affordable advances in biomedicine and technology to be delivered to patients within a humanistic framework of clinical practice that recognises the patient as a person and which takes full account of his/her stories, values, preferences, goals, aspirations, fears, worries, hopes, cultural context and which responds to his/her psychological, emotional, spiritual and social necessities

  13. Why human health and health ethics must be central to climate change deliberations.

    Directory of Open Access Journals (Sweden)

    Jerome Amir Singh

    Full Text Available Jerome Singh argues that health ethics principles must be afforded equal status to economics principles in climate change deliberations, and that the health community must play more of a leadership role.

  14. Installing an Ethics Pledge within K-12 Academia: A Restoration of Humanism

    Science.gov (United States)

    McBath, Gabrielle

    2012-01-01

    In May 2009, 33 Harvard M.B.A. Candidates proposed and published an ethics pledge entitled the M.B.A. Oath. It is a "voluntary student-led pledge that the goal of business managers is to 'serve the greater good.' It promises that Harvard M.B.A.[s] will act responsibly, ethically, and refrain from advancing their 'own narrow ambitions' at the…

  15. Ethics and Human Person According to Hispanic Ratiovitalism: Contributions of Julián Marías’s Philosophy

    Directory of Open Access Journals (Sweden)

    José Marcelo Siviero

    2009-08-01

    Full Text Available This paper intends to expose and analyze the arguments of philosopher Julián Marías regarding the problem of ethics of the human person, from the approach of human life and the metaphysical anthropology. A member of the “School of Madrid”, his thinking has been inspired by the philosophy of Ortega y Gasset. This paper seeks to recover that influence’s context, to introduce the main concepts of its theoretical model, and to present their considerations about life as a projective, biographical argument, an installation of the circumstances and mundane situations, as ways of constructing the person.

  16. A sense of the mysterious science and the human spirit

    CERN Document Server

    Lightman, Alan

    2006-01-01

    From the bestselling author of Einstein's Dreams comes this lyrical and insightful collection of science writing that delves into the mysteries of the scientific process and exposes its beauty and intrigue.In these brilliant essays, Lightman explores the emotional life of science, the power of imagination, the creative moment, and the alternate ways in which scientists and humanists think about the world. Along the way, he provides in-depth portraits of some of the great geniuses of our time, including Albert Einstein, Richard Feynman, Edward Teller, and astronomer Vera Rubin. Thoughtful, beautifully written, and wonderfully original, A Sense of the Mysterious confirms Alan Lightman's unique position at the crossroads of science and art.

  17. MEDICAL GENETICS AND ETHICS

    Directory of Open Access Journals (Sweden)

    Vladimir TRAJKOVSKI

    1999-05-01

    Full Text Available Fast development of medical genetics and it’s subdisciplines is noticed in last thirty years. Modern diagnostic methods made possible to establish human genome and its impairment. In human genetics, ethic is main principle in working. Ethic is science about biggest goodness for human or society, and its aim pro­tecting human health.Today's conditions for leaving and science development open a wide way for ethical approaches, but also for non-ethical manipulations with human even before his conception. We must keep to attitude that without law, with our behavior will must conduct our conscience. It is best to have neutral eugenetic attitude, which allows free ethical choice of each individual, in any case, for the well being of man.

  18. Contextual Sensing: Integrating Contextual Information with Human and Technical Geo-Sensor Information for Smart Cities.

    Science.gov (United States)

    Sagl, Günther; Resch, Bernd; Blaschke, Thomas

    2015-07-14

    In this article we critically discuss the challenge of integrating contextual information, in particular spatiotemporal contextual information, with human and technical sensor information, which we approach from a geospatial perspective. We start by highlighting the significance of context in general and spatiotemporal context in particular and introduce a smart city model of interactions between humans, the environment, and technology, with context at the common interface. We then focus on both the intentional and the unintentional sensing capabilities of today's technologies and discuss current technological trends that we consider have the ability to enrich human and technical geo-sensor information with contextual detail. The different types of sensors used to collect contextual information are analyzed and sorted into three groups on the basis of names considering frequently used related terms, and characteristic contextual parameters. These three groups, namely technical in situ sensors, technical remote sensors, and human sensors are analyzed and linked to three dimensions involved in sensing (data generation, geographic phenomena, and type of sensing). In contrast to other scientific publications, we found a large number of technologies and applications using in situ and mobile technical sensors within the context of smart cities, and surprisingly limited use of remote sensing approaches. In this article we further provide a critical discussion of possible impacts and influences of both technical and human sensing approaches on society, pointing out that a larger number of sensors, increased fusion of information, and the use of standardized data formats and interfaces will not necessarily result in any improvement in the quality of life of the citizens of a smart city. This article seeks to improve our understanding of technical and human geo-sensing capabilities, and to demonstrate that the use of such sensors can facilitate the integration of different

  19. Beyond the 'embryo question': human embryonic stem cell ethics in the context of biomaterial donation in the UK.

    Science.gov (United States)

    Bahadur, G; Morrison, M; Machin, L

    2010-12-01

    Discussion about the ethics of human embryonic stem cell (ESC) research in the UK tends to be dominated by the divisive and potentially intractable issue of the moral status of the embryo. This can have the effect of silencing or marginalizing other concerns, especially in the context of public engagement with science in this field. One such area of potential public concern is the donation of oocytes and embryos to stem cell research. Contemporary research on the views of donors and potential donors about a wide range of biomaterials, from solid organs to gametes and bone marrow, is reviewed and used to illustrate the range and types of ethical concerns articulated by this important group of stakeholders. Attitudes to donation are found to vary according to the type of tissue being donated or collected, the purpose for which donation is being sought and the nature of the recipient of the donation. Pertinently, attitudes towards donating oocytes are found to differ in some respects from donation of embryos or fetal tissue. The implications of these findings for ensuring ethically robust informed consent and publicly acceptable sourcing of human biomaterials for stem cell research are then considered.

  20. Contributions of skin and muscle afferent input to movement sense in the human hand.

    Science.gov (United States)

    Cordo, Paul J; Horn, Jean-Louis; Künster, Daniela; Cherry, Anne; Bratt, Alex; Gurfinkel, Victor

    2011-04-01

    In the stationary hand, static joint-position sense originates from multimodal somatosensory input (e.g., joint, skin, and muscle). In the moving hand, however, it is uncertain how movement sense arises from these different submodalities of proprioceptors. In contrast to static-position sense, movement sense includes multiple parameters such as motion detection, direction, joint angle, and velocity. Because movement sense is both multimodal and multiparametric, it is not known how different movement parameters are represented by different afferent submodalities. In theory, each submodality could redundantly represent all movement parameters, or, alternatively, different afferent submodalities could be tuned to distinctly different movement parameters. The study described in this paper investigated how skin input and muscle input each contributes to movement sense of the hand, in particular, to the movement parameters dynamic position and velocity. Healthy adult subjects were instructed to indicate with the left hand when they sensed the unseen fingers of the right hand being passively flexed at the metacarpophalangeal (MCP) joint through a previously learned target angle. The experimental approach was to suppress input from skin and/or muscle: skin input by anesthetizing the hand, and muscle input by unexpectedly extending the wrist to prevent MCP flexion from stretching the finger extensor muscle. Input from joint afferents was assumed not to play a significant role because the task was carried out with the MCP joints near their neutral positions. We found that, during passive finger movement near the neutral position in healthy adult humans, both skin and muscle receptors contribute to movement sense but qualitatively differently. Whereas skin input contributes to both dynamic position and velocity sense, muscle input may contribute only to velocity sense.

  1. Sensing human hand motions for controlling dexterous robots

    Science.gov (United States)

    Marcus, Beth A.; Churchill, Philip J.; Little, Arthur D.

    1988-01-01

    The Dexterous Hand Master (DHM) system is designed to control dexterous robot hands such as the UTAH/MIT and Stanford/JPL hands. It is the first commercially available device which makes it possible to accurately and confortably track the complex motion of the human finger joints. The DHM is adaptable to a wide variety of human hand sizes and shapes, throughout their full range of motion.

  2. Biomedical ethics.

    Science.gov (United States)

    Walters, LeRoy

    1985-10-25

    An overview is provided of bioethical issues recently under discussion in the United States. Six topics dominated the field in 1984 and early 1985: human gene therapy; in vitro fertilization and research with human embryos; appropriate care for dying patients, both adults and newborns; organ transplantation; resource allocation and payment for health care services; and the role of hospital ethics committees in medical decision making. Walters focuses on three of these topics: (1) the issuing of standards for somatic-cell gene therapy; (2) developments in the death and dying arena, including state living will legislation, the emergence of a viewpoint that artificial nutrition and hydration are not qualitatively different from respiratory life-support systems, and federal efforts to regulate appropriate treatment for handicapped newborns; and (3) the growing support among medical organizations for hospital ethics committees.

  3. The Ethical, Legal, and Social Implications Program of the National Human Genome Research Institute: reflections on an ongoing experiment.

    Science.gov (United States)

    McEwen, Jean E; Boyer, Joy T; Sun, Kathie Y; Rothenberg, Karen H; Lockhart, Nicole C; Guyer, Mark S

    2014-01-01

    For more than 20 years, the Ethical, Legal, and Social Implications (ELSI) Program of the National Human Genome Research Institute has supported empirical and conceptual research to anticipate and address the ethical, legal, and social implications of genomics. As a component of the agency that funds much of the underlying science, the program has always been an experiment. The ever-expanding number of issues the program addresses and the relatively low level of commitment on the part of other funding agencies to support such research make setting priorities especially challenging. Program-supported studies have had a significant impact on the conduct of genomics research, the implementation of genomic medicine, and broader public policies. The program's influence is likely to grow as ELSI research, genomics research, and policy development activities become increasingly integrated. Achieving the benefits of increased integration while preserving the autonomy, objectivity, and intellectual independence of ELSI investigators presents ongoing challenges and new opportunities.

  4. Modeling and remote sensing of human induced water cycle change

    Science.gov (United States)

    Pokhrel, Yadu N.

    2016-04-01

    The global water cycle has been profoundly affected by human land-water management especially during the last century. Since the changes in water cycle can affect the functioning of a wide range of biophysical and biogeochemical processes of the Earth system, it is essential to account for human land-water management in land surface models (LSMs) which are used for water resources assessment and to simulate the land surface hydrologic processes within Earth system models (ESMs). During the last two decades, noteworthy progress has been made in modeling human impacts on the water cycle but sufficient advancements have not yet been made, especially in representing human factors in large-scale LSMs toward integrating them into ESMs. In this study, an integrated modeling framework of continental-scale water cycle, with explicit representation of climate and human induced forces (e.g., irrigation, groundwater pumping) is developed and used to reconstruct the observed water cycle changes in the past and to attribute the observed changes to climatic and human factors. The new model builds upon two different previously developed models: a global LSM called the Human Impacts and GroundWater in the MATSIRO (HiGW-MAT) and a high-resolution regional groundwater model called the LEAF-Hydro-Flood. The model is used to retro-simulate the hydrologic stores and fluxes in close dialogue with in-situ and GRACE satellite based observations at a wide range of river basin scales around the world, with a particular focus on the changes in groundwater dynamics in northwest India, Pakistan, and the High Plains and Central Valley aquifers in the US.

  5. Ethical and policy issues surrounding the donation of cryopreserved and fresh embryos for human embryonic stem cell research.

    Science.gov (United States)

    Cohen, Cynthia B

    2009-06-01

    The use of human embryos in human embryonic stem cell (hESC) research raises significant ethical and policy issues associated with their donation. Recent research conducted in several countries assesses the percent of persons with cryopreserved and fresh supernumerary embryos willing to donate them for research, their reasons for considering this option, and the concerns they raise about its personal import. Such research provides new insights into rising ethical and policy questions associated with embryo donation for hESC research that should be addressed. In response to such questions, it is argued here that consent to the donation of supernumerary embryos for hESC research should be sought in two or three stages, depending on whether fresh or frozen embryos are at issue, in order to provide patients and their partners with sufficient time and information before they make a final decision. In addition, steps should be taken to support the voluntariness of their decisions by having personnel other than the treating reproductive specialist or stem cell investigators solicit their consent. Prospective embryo donors should also be given a choice about the uses to which hESCs derived from their donated embryos will be put in order to honor their ethical convictions and ensure that there are sufficient embryos for this research. The well-being and rights of those who donate embryos for this research require the sort of support and protection that can be provided by an ethical and policy framework that allows hESC investigations to move forward according to standards that are transparent and that resound with public values.

  6. The New World of Human Genetics: A dialogue between Practitioners & the General Public on Ethical, Legal & Social Implications of the Human Genome Project

    Energy Technology Data Exchange (ETDEWEB)

    Schofield, Amy

    2014-12-08

    The history and reasons for launching the Human Genome project and the current uses of genetic human material; Identifying and discussing the major issues stemming directly from genetic research and therapy-including genetic discrimination, medical/ person privacy, allocation of government resources and individual finances, and the effect on the way in which we perceive the value of human life; Discussing the sometimes hidden ethical, social and legislative implications of genetic research and therapy such as informed consent, screening and preservation of genetic materials, efficacy of medical procedures, the role of the government, and equal access to medical coverage.

  7. Gene-culture interaction and the evolution of the human sense of fairness.

    Science.gov (United States)

    Liu, Tru-Gin; Lu, Yao

    2016-08-26

    How Darwinian evolution would produce creatures with the proclivity of Darwinian generosity, most of them voluntarily giving up the immediate benefit for themselves or their genes, remains a puzzle. This study targets a problem, the origin of human sense of fairness, and uses fairness-related genes and the social manipulation of Darwinian generosity as the key variables underlying the human sense of fairness, inequity aversion, as well as their relationships within cooperation, and the anticipation foresight of the way relationships are affected by resource division, given the assumption of randomly matched partners. Here we suggest a model in which phenotype will gradually converge towards the perfect sense of fairness along with the prospect of cooperation. Later, the sense of fairness will decrease but it is never extinct. Where social manipulation of Darwinian generosity overshadows genetics, the sense of fairness could be acute to the degree of social manipulation. Above all, there still exists a threshold in the degree of social manipulation, beyond which altruism dominates selfishness in human cooperation. Finally, we propose three new directions toward more realistic scenarios stimulated by recent development of the synergy between statistical physics, network science and evolutionary game theory.

  8. Gene–culture interaction and the evolution of the human sense of fairness

    Science.gov (United States)

    Liu, Tru-Gin; Lu, Yao

    2016-01-01

    How Darwinian evolution would produce creatures with the proclivity of Darwinian generosity, most of them voluntarily giving up the immediate benefit for themselves or their genes, remains a puzzle. This study targets a problem, the origin of human sense of fairness, and uses fairness-related genes and the social manipulation of Darwinian generosity as the key variables underlying the human sense of fairness, inequity aversion, as well as their relationships within cooperation, and the anticipation foresight of the way relationships are affected by resource division, given the assumption of randomly matched partners. Here we suggest a model in which phenotype will gradually converge towards the perfect sense of fairness along with the prospect of cooperation. Later, the sense of fairness will decrease but it is never extinct. Where social manipulation of Darwinian generosity overshadows genetics, the sense of fairness could be acute to the degree of social manipulation. Above all, there still exists a threshold in the degree of social manipulation, beyond which altruism dominates selfishness in human cooperation. Finally, we propose three new directions toward more realistic scenarios stimulated by recent development of the synergy between statistical physics, network science and evolutionary game theory. PMID:27562008

  9. Bearing response-ability: theater, ethics and medical education.

    Science.gov (United States)

    Rossiter, Kate

    2012-03-01

    This paper addresses a growing concern within the medical humanities community regarding the perceived need for a more empathically-focused medical curricula, and advocates for the use of creative pedagogical forms as a means to attend to issues of suffering and relationality. Drawing from the ethical philosophy of Emmanuel Levinas, I critique the notion of empathy on the basis that it erases difference and disregards otherness. Rather, I propose that the concept of empathy may be usefully replaced with that of ethical responsibility, which suggests a shared sense of humanity outside the boundaries of presumed knowledge of the other. To illustrate this argument, I theorize the importance of theater within medical education. Theater, I argue, may engender ethical responsibility in the Levinasian sense, and thus may allow learners to differently engage with the experience of the suffering other. As such, I examine Margaret Edson's widely used play Wit as a platform for such an ethical encounter to occur. Thus, rather than working to understand the value of theater in medical education in terms of knowledge and skill acquisition, I theorize that its primacy within medical curricula arises from its ethical/relational potential, or potential to engender new forms of inter-human relationality.

  10. The effect of ethics training on students recognizing ethical violations and developing moral sensitivity.

    Science.gov (United States)

    Baykara, Zehra Gocmen; Demir, Sevil Guler; Yaman, Sengul

    2015-09-01

    Moral sensitivity is a life-long cognitive ability. It is expected that nurses who work in a professional purpose at "curing human beings" should have a highly developed moral sensitivity. The general opinion is that ethics education plays a significant role in this sense to enhance the moral sensitivity in terms of nurses' professional behaviors and distinguish ethical violations. This study was conducted as intervention research for the purpose of determining the effect of the ethics training on fourth-year students of the nursing department recognizing ethical violations experienced in the hospital and developing ethical sensitivity. The study was conducted with 50 students, with 25 students each in the experiment and control groups. Students in the experiment group were provided ethics training and consultancy services. The data were collected through the data collection form, which consists of questions on the socio-demographic characteristics and ethical sensitivity of the students, Moral Sensitivity Questionnaire, and the observation form on ethical principle violations/protection in the clinic environment. The data were digitized on the computer with the SPSS for Windows 13.0 program. The data were evaluated utilizing number, percentile calculation, paired samples t-test, Wilcoxon test, and the McNemar test. The total Moral Sensitivity Questionnaire pre-test score averages of students in the experiment group were determined to be 93.88 ± 13.57, and their total post-test score averages were determined to be 89.24 ± 15.90. The total pre-test score averages of students in the control group were determined to be 91.48 ± 17.59, and their total post-test score averages were determined to be 97.72 ± 19.91. In the study, it was determined that the post-training ethical sensitivity of students in the experiment group increased; however, this was statistically not significant. Furthermore, it was determined that the number of ethical principle protection

  11. The ethics of killing human/great-ape chimeras for their organs: a reply to Shaw et al.

    Science.gov (United States)

    Palacios-González, César

    2016-06-01

    The aim of this paper is to critically examine David Shaw, Wybo Dondorp, and Guido de Wert's arguments in favour of the procurement of human organs from human/nonhuman-primate chimeras, specifically from great-ape/human chimeras. My main claim is that their arguments fail and are in need of substantial revision. To prove this I first introduce the topic, and then reconstruct Shaw et al.'s position and arguments. Next, I show that Shaw et al.: (1) failed to properly apply the subsidiarity and proportionality principles; (2) neglected species overlapping cases in their ethical assessment; (3) ignored the ethics literature on borderline persons; and (4) misunderstood McMahan's two-tiered moral theory. These mistakes render an important part of their conclusions either false or problematic to the point that they would no longer endorse them. Finally I will briefly mention a possible multipolar solution to the human organ shortage problem that would reduce the need for chimeras' organs.

  12. Ethical considerations of randomized control trials with human participants in dentistry. A reflective analysis.

    Science.gov (United States)

    Chen, Eric

    2013-01-01

    A potential conflict is built into the roles of dentists and researchers with regard to ethical principles such as beneficence, nonmaleficence, respect for autonomy, and justice. The practitioner has an obligation to do what is believed to be best for the individual patient: the dentist as researcher has an obligation to use rigorous experimental methods, including randomized control trials (RCTs) to discover what is best for patients generally, including the investigation of experimental modalities. This is the equipoise problem-how can a professional be assured of offering the most beneficial treatment available if only using approaches that have worked in the past? This essay explores the ethical foundations for this challenge and proposes a groundwork for balancing ethical obligations to patients and the needs for scientific and public health advances.

  13. Research ethics in the dynamic of scientific field: challenges in the building of guidelines for social sciences and humanities.

    Science.gov (United States)

    Guerriero, Iara Coelho Zito; Bosi, Maria Lúcia Magalhães

    2015-09-01

    The development of guidelines on research ethics for social science and humanities (SSH) takes place in the scientific field, marked by disputes aimed at the establishment of hegemonic scientific standard. In Brazil, the National Health Council is responsible for approving these guidelines, which involve certain specificities. Based on the authors' experience in the SSH Working Group of the National Commission on Research Ethics (GT CHS / CONEP), this article presents the process of development of guidelines for SSH, and some its challenges: the distance between the statutory guarantee and the effective execution of guidelines; the biomedical hegemony and the marginal position of the SSH in the CEP / CONEP system; the inadequacy of the current resolution facing the research features in CHS; the use of the concept of risk in guidelines aimed at SSH in the health area. Some interfaces and tensions in the debate between scientific merit and ethical evaluation are also discussed. The analysis highlights important impasses and difficulties regarding inter-paradigmatic dialogue in health research, considered the characteristics of the different traditions, the CONEP's heavily relying on the positivist perspective and the defense of that paradigm hegemony.

  14. Trafficking in Human Beings for the Purpose of Organ Removal and the Ethical and Legal Obligations of Healthcare Providers.

    Science.gov (United States)

    Caulfield, Timothy; Duijst, Wilma; Bos, Mike; Chassis, Iris; Codreanu, Igor; Danovitch, Gabriel; Gill, John; Ivanovski, Ninoslav; Shin, Milbert

    2016-02-01

    Physicians and other health care professionals seem well placed to play a role in the monitoring and, perhaps, in the curtailment of the trafficking in human beings for the purpose of organ removal. They serve as important sources of information for patients and may have access to information that can be used to gain a greater understanding of organ trafficking networks. However, well-established legal and ethical obligations owed to their patients can create challenging policy tensions that can make it difficult to implement policy action at the level of the physician/patient. In this article, we explore the role-and legal and ethical obligations-of physicians at 3 key stages of patient interaction: the information phase, the pretransplant phase, and the posttransplant phase. Although policy challenges remain, physicians can still play a vital role by, for example, providing patients with a frank disclosure of the relevant risks and harms associated with the illegal organ trade and an honest account of the physician's own moral objections. They can also report colleagues involved in the illegal trade to an appropriate regulatory authority. Existing legal and ethical obligations likely prohibit physicians from reporting patients who have received an illegal organ. However, given the potential benefits that may accrue from the collection of more information about the illegal transactions, this is an area where legal reform should be considered.

  15. Ethical and legal considerations regarding the ownership and commercial use of human biological materials and their derivatives

    Directory of Open Access Journals (Sweden)

    Petrini C

    2012-09-01

    Full Text Available Carlo PetriniItalian National Institute of Health, Rome, ItalyAbstract: This article considers some of the ethical and legal issues relating to the ownership and use – including for commercial purposes – of biological material and products derived from humans. The discussion is divided into three parts: after first examining the general notion of ownership, it moves to the particular case of possible commercial use, and finally reflects on the case in point in the light of the preceding considerations. Units of cord blood donated altruistically for transplantation and which are found unsuitable for storage and transplantation, or which become unsuitable while stored in biobanks, are taken as an example. These cord-blood units can be discarded together with other biological waste, or they can be used for research or the development of blood-derived products such as platelet gel. Several ethical questions (eg, informed consent, property, distribution of profits, and others arise from these circumstances. In this regard, some criteria and limits to use are proposed.Keywords: bioethics, biological specimen banks, cord-blood stem cell transplantation, ethics, informed consent, legislation

  16. Ambient Assisted Living Systems in the Context of Human Centric Sensing and IoT Concept

    DEFF Research Database (Denmark)

    Zaric, Nicola; Pejanovic-Djurisic, Milica; Mihovska, Albena Dimitrova

    2016-01-01

    This paper proposes the concept of Human Centric Sensing in the context of Internet of Things and Ambient Assisted Living. The paper uses a case study to present and analyze the proposed idea, and identifies the main challenges and open issues that require research and policy attention....

  17. "Literariness," Formalism, and Sense Making: The Line and Stanza Structure of Human Thought.

    Science.gov (United States)

    Gee, James Paul

    1989-01-01

    Uses the "line and stanza" method to analyze and compare texts representing different cultural backgrounds and ages. Proposes that the textual characteristics identified by the Formalists as the measure of literature are actually the hallmarks of a cross-cultural human capacity for making deep sense of experience. (FMW)

  18. Ambulatory human motion tracking by fusion of inertial and magnetic sensing with adaptive actuation

    NARCIS (Netherlands)

    Schepers, H. Martin; Roetenberg, Daniel; Veltink, Peter H.

    2010-01-01

    Over the last years, inertial sensing has proven to be a suitable ambulatory alternative to traditional human motion tracking based on optical position measurement systems, which are generally restricted to a laboratory environment. Besides many advantages, a major drawback is the inherent drift cau

  19. [A study on origin of genetic ethics problem and countermeasure].

    Science.gov (United States)

    Cheng, Yan-Ping

    2008-03-01

    The genetic ethical problem is one of problems which are the most disputable or difficult to resolve perfectly in the fields of life science. In these years the research for the problems is being concentrated on the types of genetic ethical problem and the ways to resolve them. But the systematic research for origin of genetic ethical problem is rare to be known. Thus it seems to be short of theoretical support to bring forward corresponding countermeasure. In this paper we focus on the evolving germ of genetic ethical problem and its evolving rule from the twofold views of human biological evolution and cultural evolution. A human being is a double offspring with biological evolution and cultural evolution . And he is a species which has both biological and cultural attribute on the earth. Through comparing and studying human biological evolution , cultural evolution, and characteristics of both biological attribute and cultural attribute, we bring forward a viewpoint that all ethical problems originate from a conflict originating from interplay of human biological evolution and cultural evolution. We intend to seek for the gist of theory and practice in order to research for genetic ethical problem and put forward some corresponding countermeasures. At the same time we'll advance a series of corresponding countermeasures of genetic ethical problem. The final aim in the paper is that not only some of our opinions will be admitted, but also through learning and understanding genetic ethical problem and its origin, the decision-makers and investigators in genetics field will be promoted to have more sense of fate and responsibility , so that the average public are able to misunderstand less and understand more for studying and genetics applying. We all work hard for genetics career to make it in healthy and continuing development and give a lot of happiness to human beings.

  20. Molecular Vibration-Sensing Component in Human Olfaction

    Science.gov (United States)

    Vamvakias, Manolis; Ragoussis, Nikitas; Skoulakis, Efthimios M. C.; Turin, Luca

    2013-01-01

    Whether olfaction recognizes odorants by their shape, their molecular vibrations, or both remains an open and controversial question. A convenient way to address it is to test for odor character differences between deuterated and undeuterated odorant isotopomers, since these have identical ground-state conformations but different vibrational modes. In a previous paper (Franco et al. (2011) Proc Natl Acad Sci USA 108:9, 3797-802) we showed that fruit flies can recognize the presence of deuterium in odorants by a vibrational mechanism. Here we address the question of whether humans too can distinguish deuterated and undeuterated odorants. A previous report (Keller and Vosshall (2004) Nat Neurosci 7:4, 337-8) indicated that naive subjects are incapable of distinguishing acetophenone and d-8 acetophenone. Here we confirm and extend those results to trained subjects and gas-chromatography [GC]-pure odorants. However, we also show that subjects easily distinguish deuterated and undeuterated musk odorants purified to GC-pure standard. These results are consistent with a vibrational component in human olfaction. PMID:23372854

  1. Molecular vibration-sensing component in human olfaction.

    Directory of Open Access Journals (Sweden)

    Simon Gane

    Full Text Available Whether olfaction recognizes odorants by their shape, their molecular vibrations, or both remains an open and controversial question. A convenient way to address it is to test for odor character differences between deuterated and undeuterated odorant isotopomers, since these have identical ground-state conformations but different vibrational modes. In a previous paper (Franco et al. (2011 Proc Natl Acad Sci USA 108:9, 3797-802 we showed that fruit flies can recognize the presence of deuterium in odorants by a vibrational mechanism. Here we address the question of whether humans too can distinguish deuterated and undeuterated odorants. A previous report (Keller and Vosshall (2004 Nat Neurosci 7:4, 337-8 indicated that naive subjects are incapable of distinguishing acetophenone and d-8 acetophenone. Here we confirm and extend those results to trained subjects and gas-chromatography [GC]-pure odorants. However, we also show that subjects easily distinguish deuterated and undeuterated musk odorants purified to GC-pure standard. These results are consistent with a vibrational component in human olfaction.

  2. Research Ethics I: Responsible Conduct of Research (RCR)--Historical and Contemporary Issues Pertaining to Human and Animal Experimentation

    Science.gov (United States)

    Horner, Jennifer; Minifie, Fred D.

    2011-01-01

    Purpose: In this series of articles--"Research Ethics I", "Research Ethics II", and "Research Ethics III"--the authors provide a comprehensive review of the 9 core domains for the responsible conduct of research (RCR) as articulated by the Office of Research Integrity. In "Research Ethics I", they present a historical overview of the evolution of…

  3. Research Ethics I: Responsible Conduct of Research (RCR)--Historical and Contemporary Issues Pertaining to Human and Animal Experimentation

    Science.gov (United States)

    Horner, Jennifer; Minifie, Fred D.

    2011-01-01

    Purpose: In this series of articles--"Research Ethics I", "Research Ethics II", and "Research Ethics III"--the authors provide a comprehensive review of the 9 core domains for the responsible conduct of research (RCR) as articulated by the Office of Research Integrity. In "Research Ethics I", they present a historical overview of the evolution of…

  4. Access and use of human tissues from the developing world: ethical challenges and a way forward using a tissue trust.

    Science.gov (United States)

    Emerson, Claudia I; Singer, Peter A; Upshur, Ross E G

    2011-01-25

    Scientists engaged in global health research are increasingly faced with barriers to access and use of human tissues from the developing world communities where much of their research is targeted. In part, the problem can be traced to distrust of researchers from affluent countries, given the history of 'scientific-imperialism' and 'biocolonialism' reflected in past well publicized cases of exploitation of research participants from low to middle income countries. To a considerable extent, the failure to adequately engage host communities, the opacity of informed consent, and the lack of fair benefit-sharing have played a significant role in eroding trust. These ethical considerations are central to biomedical research in low to middle income countries and failure to attend to them can inadvertently contribute to exploitation and erode trust. A 'tissue trust' may be a plausible means for enabling access to human tissues for research in a manner that is responsive to the ethical challenges considered. Preventing exploitation and restoring trust while simultaneously promoting global health research calls for innovative approaches to human tissues research. A tissue trust can reduce the risk of exploitation and promote host capacity as a key benefit.

  5. Access and use of human tissues from the developing world: ethical challenges and a way forward using a tissue trust

    Directory of Open Access Journals (Sweden)

    Upshur Ross EG

    2011-01-01

    Full Text Available Abstract Background Scientists engaged in global health research are increasingly faced with barriers to access and use of human tissues from the developing world communities where much of their research is targeted. In part, the problem can be traced to distrust of researchers from affluent countries, given the history of 'scientific-imperialism' and 'biocolonialism' reflected in past well publicized cases of exploitation of research participants from low to middle income countries. Discussion To a considerable extent, the failure to adequately engage host communities, the opacity of informed consent, and the lack of fair benefit-sharing have played a significant role in eroding trust. These ethical considerations are central to biomedical research in low to middle income countries and failure to attend to them can inadvertently contribute to exploitation and erode trust. A 'tissue trust' may be a plausible means for enabling access to human tissues for research in a manner that is responsive to the ethical challenges considered. Summary Preventing exploitation and restoring trust while simultaneously promoting global health research calls for innovative approaches to human tissues research. A tissue trust can reduce the risk of exploitation and promote host capacity as a key benefit.

  6. The Social and Ethical Acceptability of NBICs for Purposes of Human Enhancement: Why Does the Debate Remain Mired in Impasse?

    Science.gov (United States)

    Béland, Jean-Pierre; Patenaude, Johane; Legault, Georges A; Boissy, Patrick; Parent, Monelle

    2011-12-01

    The emergence and development of convergent technologies for the purpose of improving human performance, including nanotechnology, biotechnology, information sciences, and cognitive science (NBICs), open up new horizons in the debates and moral arguments that must be engaged by philosophers who hope to take seriously the question of the ethical and social acceptability of these technologies. This article advances an analysis of the factors that contribute to confusion and discord on the topic, in order to help in understanding why arguments that form a part of the debate between transhumanism and humanism result in a philosophical and ethical impasse: 1. The lack of clarity that emerges from the fact that any given argument deployed (arguments based on nature and human nature, dignity, the good life) can serve as the basis for both the positive and the negative evaluation of NBICs. 2. The impossibility of providing these arguments with foundations that will enable others to deem them acceptable. 3. The difficulty of applying these same arguments to a specific situation. 4. The ineffectiveness of moral argument in a democratic society. The present effort at communication about the difficulties of the argumentation process is intended as a necessary first step towards developing an interdisciplinary response to those difficulties.

  7. The race toward 'ethically universally acceptable' human pluripotent (embryonic-like) stem cells: only a problem of sources?

    Science.gov (United States)

    Neri, Demetrio

    2011-06-01

    Over the past few years, several proposals aimed at procuring human pluripotent (embryonic-like) stem cells without involving the destruction of a human embryo have been proposed and widely discussed. This article focuses on a basic aspect of the debate, namely the plausibility of one or more of these new proposals being able to meet the ethical requirements that those who regard the human embryo as sacred have tried to impose on stem cells research in the last ten years. The thesis of the article is that focusing the discussion only on the sources of stem cells has prevented a full understanding of the foundation, meaning and scope of these ethical requirements. To substantiate this thesis, the article takes into consideration two issues: the first has to do with the potential of the cells obtained through some of the new approaches (iPS included), the second (and decisive) with the argument of the 'indirect complicity', applied to the use of 'contaminated' knowledge.

  8. Ethical Issues for Clinical Studies That use Human Embryonic Stem Cells: The 2014 Revisions to the Japanese Guidelines.

    Science.gov (United States)

    Mizuno, Hiroshi

    2015-10-01

    The use of human embryonic stem cells (hESCs) in clinical studies has been expanding in recent years. The application of hESCs in clinical studies raises ethical issues from a different standpoint compared with the use of other types of stem cells. In Japan, the Guidelines on the Derivation of Human Embryonic Stem Cells, and Guidelines on the Distribution and Utilization of Human Embryonic Stem Cells had been revised for clinical studies in 2014. In the revised guidelines, the method for protection of personal information was changed to offer the choice between unlinkable anonymization and linkable anonymization, to enable the use of information on diseases suffered by donors and the assurance of traceability for safety. Procedures for re-consent are generally prohibited out of consideration for donors' feelings. However, obtaining re-consent is permitted when consent for re-consent has been received in advance and approval has been given by an ethical review board, in which case the donors may be contacted. Incidental findings obtained from hESCs are not disclosed individually to donors, while the research results should be actively published for the common good. These guidelines have enabled the derivation, distribution, and use of hESCs for clinical studies.

  9. THE BRANDING OF ETHICS: A Multidisciplinary Investigation into the Ethical Branding Phenomenon in the UK

    OpenAIRE

    Zhang, Lifu

    2006-01-01

    Ethical considerations are a potentially powerful influence on consumer purchasing decisions. Marketers have begun to recognize the need to incorporate business ethics into their marketing activities. The practice of 'ethical branding' is a relatively new phenomenon and previous studies have been mainly focusing on how consumers make sense of it, rather than how and why marketers position their products as ethical brands. This study aims to explore the motives behind ethical branding decision...

  10. Managerji HRM in njihove etične dileme = Human Resource Managers and Their Ethical Dilemma

    Directory of Open Access Journals (Sweden)

    Mateja Primožič

    2011-09-01

    Full Text Available Douglas Renwick (2003 said that the personnel function plays therole of guardian of employees’ wellbeing, but on the other hand, hesaid that personnel managers also tamper with the wellbeing of employees.Looking at Renwick’s theory through Ulrich’s model of personnelmanagers as guardians of employees’ wellbeing, they play therole of strategic partners, managers of the changes and the role of theemployees representatives. Gantz and Hayes (in Payne and Wayland,1999 explicated a few fields where we can talk of ethical conflict whileperforming these roles: discrimination, psychological tests, anti-unionbehaviour, design of work flow, job insecurity, discipline, confidentiality,privacy, and firing because of technological redundancy. In this paperwe explore the field of potential and real ethical conflicts of humanresource managers.What are the most important values of humanresources managers? In which areas do ethical conflicts occur?And how do they solve these conflicts on an everyday basis? We usedquestionnaires to gather data on these issues. We found out that managerswho are in leading positions suffer the most, next are those whohave had long tenure. In this situation ethical codes don’t help much.

  11. Ethics or Morals: Understanding Students' Values Related to Genetic Tests on Humans

    Science.gov (United States)

    Lindahl, Mats Gunnar

    2009-01-01

    To make meaning of scientific knowledge in such a way that concepts and values of the life-world are not threatened is difficult for students and laymen. Ethics and morals pertaining to the use of genetic tests for hereditary diseases have been investigated and discussed by educators, anthropologists, medical doctors and philosophers giving, at…

  12. Capitalizing on the Human-Animal Bond to Teach Ethics to Youth

    Science.gov (United States)

    Rusk, Clinton P.; Brubaker, Keli M.; Balschweid, Mark A.; Pajor, Edmond A.

    2005-01-01

    Unethical occurrences at major livestock shows have spurred the need to raise ethical awareness to youngsters involved in agriculture. In order to eliminate unethical behavior, it is important to understand why people make the decisions they do. This study was based on Lawrence Kohlberg's theory of moral development, which is the increasing…

  13. Ethics or Morals: Understanding Students' Values Related to Genetic Tests on Humans

    Science.gov (United States)

    Lindahl, Mats Gunnar

    2009-01-01

    To make meaning of scientific knowledge in such a way that concepts and values of the life-world are not threatened is difficult for students and laymen. Ethics and morals pertaining to the use of genetic tests for hereditary diseases have been investigated and discussed by educators, anthropologists, medical doctors and philosophers giving, at…

  14. The Production, Scientific and Therapeutic Use of Human Embryonic Stem Cell: the Ethic Concern

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This article presents opinions on use of embryonic stem cells in the scientific and ethicalliterature and in public opinion. Given the growing relevance of the debate on the limitsand licitness of the production and use of such cells, there is a pressing need to reflecton the ethical implications, which are present in this article.

  15. The Ethics of Human Freedom and Healthcare Policy: A Nursing Theoretical Perspective.

    Science.gov (United States)

    Milton, Constance L

    2015-07-01

    Global healthcare and healthcare policies are evolving with change at a swift pace. Inherent in the discussions of a person's right to choose health is the notion of freedom. The author in this column compares and contrasts bioethical views of freedom and autonomy with alternative views and possibilities by examining an ethic of freedom grounded from a different paradigm, the humanbecoming nursing theoretical perspective.

  16. Ethical issues in physiotherapy

    DEFF Research Database (Denmark)

    Præstegaard, Jeanette; Gard, Gunvor

    2012-01-01

    Background: An important aspect of physiotherapy professional autonomy is the ethical code of the profession, both collectively and for the individual member of the profession. The aim of this study is to explore and add additional insight into the nature and scope of ethical issues as they are u......Background: An important aspect of physiotherapy professional autonomy is the ethical code of the profession, both collectively and for the individual member of the profession. The aim of this study is to explore and add additional insight into the nature and scope of ethical issues......: The ideal of being beneficent toward the patient. Here, the ethical issues uncovered in the interviews were embedded in three code-groups: 1) ethical issues related to equality; 2) feeling obligated to do one's best; and 3) transgression of boundaries. Conclusions: In an ethical perspective, physiotherapy...... in private practice is on a trajectory toward increased professionalism. Physiotherapists in private practice have many reflections on ethics and these reflections are primarily based on individual common sense arguments and on deontological understandings. As physiotherapy by condition is characterized...

  17. Ethical problems in radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Shrader-Frechette, K.; Persson, Lars

    2001-05-01

    In this report the authors survey existing international radiation-protection recommendations and standards of the ICRP, the IAEA, and the ILO. After outlining previous work on the ethics of radiation protection, professional ethics, and the ethics of human radiation experiments, the authors review ethical thinking on seven key issues related to radiation protection and ethics. They formulate each of these seven issues in terms of alternative ethical stances: (1) equity versus efficiency, (2) health versus economics, (3) individual rights versus societal benefits, (4) due process versus necessary sacrifice, (5) uniform versus double standards, (6) stake holder consent versus management decisions, and (7) environmental stewardship versus anthropocentric standards.

  18. Matrix metalloproteinase sensing via porous silicon microcavity devices functionalized with human antibodies

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Marta; Gergely, Csilla [GES-UMR 5650, CNRS, Universite Montpellier 2, Pl. Eugene Bataillon 34095, Montpellier Cedex 5 (France); Taleb Bendiab, Chakib; Massif, Laurent; Cuisinier, Frederic [EA4203, Faculte d' Odontologie, Universite Montpellier 1, Montpellier Cedex 5 (France); Palestino, Gabriela [Facultad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosi, Av. Salvador Nava 6, 78000 San Luis Potosi (Mexico); Agarwal, Vivechana [CIICAP, Universidad Autonoma del Estado de Morelos, Av. Universidad 1001, Col Chamilpa, Cuernavaca, Mor. (Mexico)

    2011-06-15

    Porous silicon microcavity (PSiMc) structures were used as support material for specific sensing of matrix metalloproteinases (MMPs). For lower concentrations of MMP-8, the structures were tested with two types of functionalization methods. Silanization of the oxidized porous silicon structures, followed by glutaraldehyde chemistry was found to give very inconsistent results. The use of biotinilated bovine serum albumin linked to the naked PSiMc was found to be an alternative method to attach the anti MMP-8 human antibody, previously modified with streptavidin, which was further used to sense MMP-8 (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  19. Depending on Ethics

    DEFF Research Database (Denmark)

    Christensen, Anne-Marie Søndergaard

    2007-01-01

    According to the standard reception, Kierkegaard thinks of ethics as a possible stage in human life. In this paper, I do not want to contest this interpretation, but I will argue that it often overlooks how the concept of ethics plays another vital role in Kierkegaard's thinking, namely that of e...

  20. Ethical issues in biotechnology.

    Science.gov (United States)

    Polkinghorne, J C

    2000-01-01

    New ethical questions have arisen from our ability to intervene in the structure of the genome. Responsible use of this technique requires ethical evaluation in which experts, potential beneficiaries and the general public should all participate. The examples of genetically modified food and of human genetics help to illustrate the issues involved.

  1. Sensing human physiological response using wearable carbon nanotube-based fabrics

    Science.gov (United States)

    Wang, Long; Loh, Kenneth J.; Koo, Helen S.

    2016-04-01

    Flexible and wearable sensors for human monitoring have received increased attention. Besides detecting motion and physical activity, measuring human vital signals (e.g., respiration rate and body temperature) provide rich data for assessing subjects' physiological or psychological condition. Instead of using conventional, bulky, sensing transducers, the objective of this study was to design and test a wearable, fabric-like sensing system. In particular, multi-walled carbon nanotube (MWCNT)-latex thin films of different MWCNT concentrations were first fabricated using spray coating. Freestanding MWCNT-latex films were then sandwiched between two layers of flexible fabric using iron-on adhesive to form the wearable sensor. Second, to characterize its strain sensing properties, the fabric sensors were subjected to uniaxial and cyclic tensile load tests, and they exhibited relatively stable electromechanical responses. Finally, the wearable sensors were placed on a human subject for monitoring simple motions and for validating their practical strain sensing performance. Overall, the wearable fabric sensor design exhibited advances such as flexibility, ease of fabrication, light weight, low cost, noninvasiveness, and user comfort.

  2. Static Human Detection and Scenario Recognition via Wearable Thermal Sensing System

    Directory of Open Access Journals (Sweden)

    Qingquan Sun

    2017-01-01

    Full Text Available Conventional wearable sensors are mainly used to detect the physiological and activity information of individuals who wear them, but fail to perceive the information of the surrounding environment. This paper presents a wearable thermal sensing system to detect and perceive the information of surrounding human subjects. The proposed system is developed based on a pyroelectric infrared sensor. Such a sensor system aims to provide surrounding information to blind people and people with weak visual capability to help them adapt to the environment and avoid collision. In order to achieve this goal, a low-cost, low-data-throughput binary sampling and analyzing scheme is proposed. We also developed a conditioning sensing circuit with a low-noise signal amplifier and programmable system on chip (PSoC to adjust the amplification gain. Three statistical features in information space are extracted to recognize static humans and human scenarios in indoor environments. The results demonstrate that the proposed wearable thermal sensing system and binary statistical analysis method are efficient in static human detection and human scenario perception.

  3. Human tactile perception as a standard for artificial tactile sensing--a review.

    Science.gov (United States)

    Dargahi, J; Najarian, S

    2004-06-01

    In this paper, we examine the most important features of human skin tactile properties with special emphasis on the characteristics which are vital in the design of artificial systems. Contrary to the visual and auditory senses, the touch signal is not a well-defined quantity. As a result, the researchers of this field are still dealing with the basics of collecting the most relevant data. Following this, mimicking the sense of touch by producing artificial tactile skin is a challenging process. Although the sense of touch is widely distributed all over the human body, the tactile perception in the human hand is of great importance in terms of surgical and medical robotics applications. In this study, the role of various mechanoreceptors in the human hand, such as, RA, SA I, SA II, and PC units are discussed in relation to the stimuli like force, position, softness, and surface texture. Taking human hand as a suitable tactile model, the necessary engineering features of an artificial tactile sensor, such as, spatial and temporal resolutions, force sensitivity, and linearity, are being reviewed. In this work, we also report on the current and possible future applications of tactile sensors in various surgical procedures.

  4. Everyday Ethics: Reflections on Practice

    Science.gov (United States)

    Rossman, Gretchen B.; Rallis, Sharon F.

    2010-01-01

    This introductory article frames the contributions for this issue on everyday ethics--moments that demand moral considerations and ethical choices that researchers encounter. We discuss concerns raised within the research community about the tendency to observe merely obligatory ethical procedures as outlined in Human Subjects Review regulations.…

  5. An Introduction To the View of Engineering Ethics

    Institute of Scientific and Technical Information of China (English)

    铁怀江

    2013-01-01

    China has stepped onto the crucial stage of transforming from a big engineering country to a real engineering power, and striving for building a wel-off society in an al-round way. But the fact can not be neglected that the level of engineering professionalization is still very low, and the engineers are stil not wel-reputed. This calls for the fields of engineering, engineering education and even all walks of life to deeply understand the implication of engineering as profession, to cultivate the sense of engineering professional duties and to put into practive the responsibilities of engineering profession. This dissertation puts forward the basic theory of engineering ethics, including the definition of engineering ethics,the major contents and their inner logic. Special emphasis is on the view of engineering ethics of the Chinese engineering undergraduates oriented professional ethics education. It is for the first time that the author clearly puts forward the concept“engineering ethics”and has elaborated the five categories:engineering benefits human being, engineering reputation, loyalty, co-operation, and self-government in engineering. In practice, it has been put forward in this dissertation that professional ethics safeguards self-government in engineering, of which education of engineering professional ethics is the premise, in that only when one achieves self-consciousness in ethics can they achieve self-discipline, and then self-government.

  6. Scientific research on human subjects and ethics procedures at the Istituto Superiore di Sanità: a survey of the articles issued in 2001.

    Science.gov (United States)

    Rosmini, Francesco; Ferrigno, Luigina; D'Angelo, Franca; Poltronieri, Elisabetta

    2006-01-01

    Principles promoting the protection of subjects involved in biomedical research are interpreted differently within the scientific community. The purpose of this paper is to describe the attitudes of researchers working at the Istituto Superiore di Sanità (ISS) regarding the ethical implications of studies involving human beings, with particular emphasis on aspects concerning informed consent (IC) and ethics committee (EC) review. In 2001, ISS researchers published a total of 733 articles, 93 (12.7%) of which were studies involving human beings. Nearly 2/3 (60/93) were epidemiological, while the remaining 35.5% were based on laboratory data. Half (47/93) reported physical or psychological interventions or treatments on study subjects. 40.9% of articles mentioned that informed consent had been obtained and only 12.9% that approval had been given by an ethics committee. The low proportion of articles on which a protocol had been submitted the EC was due in part to the type of studies, but also to the absence of an institutional EC prior to 2001. Ethical procedures were more present in laboratory than in epidemiologic studies (IC: 69.7% vs 25.0%, p ethical awareness on the part of epidemiologists. Further efforts are needed to develop and enforce clear institutional policies regarding ethical procedures.

  7. Conflictos en ética de investigación con seres humanos Ethical conflicts in research with human subjects

    Directory of Open Access Journals (Sweden)

    Miguel H. Kottow

    2005-06-01

    Full Text Available Desde la Declaración de Helsinki 2000, se intensificó y amplió un conflictivo debate que ha cuestionado muchos aspectos de la ética de investigación con seres humanos. La polémica incluye el uso de placebos, la aplicación del concepto de equiponderación, la distinción entre ética de investigación y ética clínica, así como la diferencia entre ensayos terapéuticos y no terapéuticos. El presente artículo insiste en fortalecer todos los argumentos, parámetros y estrategias de investigación que sean necesarios para proteger a los paciente-probandos, ante todo el mantenimiento de la mejor terapia existente, el rechazo del uso de placebos, la aplicación de la equiponderación, la preservación de requerimientos terapéuticos más allá del estudio y la compensación a comunidades-huésped en la medida que ellas hayan facilitado y apoyado la investigación. La propuesta de establecer un doble estándar de ética de investigación en seres humanos, una de máximos para países desarrollados y otra de mínimos pragmáticos a aplicar en países de desarrollo precario, debe ser rechazada por contravenir las intenciones de universalizabilidad de toda prescripción ética.The Declaration of Helsinki (2000 helped trigger a major debate on many ethical aspects of research with human subjects. Topics under discussion include the use of placebos, the application of equipoise, the distinction between research ethics and clinical ethics, and the difference between therapeutic and non-therapeutic trials. This article supports tenets that serve to protect patients involved in research, especially in those aspects concerning maintenance of best existing therapy, the rejection of using placebos, support of equipoise, the assurance that required medication shall be available beyond the termination of the research project, and that appropriate compensation will obtain to host communities inasmuch as they may have facilitated and supported the project

  8. Human Resource Ethics in Malaysia: A Study of Malaysian Employees’ Perception of Business Ethics and Its Relatedness to the Local Culture

    OpenAIRE

    Kuan, Kenneth Hwai Kien

    2005-01-01

    This research presents an exploratory view of the Malaysian working professional’s attitude towards business ethics. The study was done in view of the dearth of empirical study on this topic in Malaysia. The subject of business ethics is gaining popularity, due mainly to two factors. The first is the higher level of education attained by Malaysians as a result of development. Secondly, the effect of globalisation in which the Western world, primarily led by the United States has imposed their...

  9. Tortury i egzekucje w etyce kata [TORTURES AND EXECUTIONS IN THE EXECUTIONER ETHICS

    Directory of Open Access Journals (Sweden)

    Roman Tokarczyk

    2013-06-01

    Full Text Available Article is devoted to executioner ethics in the sense capital punishment ethics.At first definitions and concepts are presented. Next: torture ethics, execution ethics,executioner ethics principles, evaluations of executioner and executioner placein culture.Author contemplates historical and cultural background connected with executionerprofession from mainly the three points of view: torture ethics, executionethics, executioner ethics in the light both deontological as utilitarian currents of ethics.

  10. The search for oneself: Introductory notes on ethics and anthropology

    Directory of Open Access Journals (Sweden)

    J.P. (Kobus Labuschagne

    2013-01-01

    Full Text Available Human beings make choices, and get caught up by their choices. One cannot escape the choices one has made. Your choices draw the picture of who you really are. Sometimes you are haunted by the dire consequences of the choices you have made. Where does the necessity of taking responsibility for yourself, and the choices you have made, take you? Ethics and moral conduct make sense only in conjunction with the moral agent – humankind. This article is an introductory reflection on ethics and anthropology. The argument develops mainly from the view of a human being as a relational being. People are inescapably relational beings – always being in relation with other human beings, and never able to sever the lifesaving ties to God as the human being’s Maker. Human beings become themselves in relation to other human beings, and ultimately in relation to the One Other, God their Creator and Re-creator.

  11. Ethical Thought on Medical Humanities Quality Cultivating%医学人文品格培养的伦理思考

    Institute of Scientific and Technical Information of China (English)

    钟声; 杨晔; 陈新

    2012-01-01

    At present, the ethical missing in the medical humanities quality in medical staff is shown as the doctor - patient relationship apathy, the poor doctor - patient communication. The way of strengthening the humanities quality cultivation in medical staff is to cany forward humane spirits, to pay attention to the humanities quality cultivation in medical staff, promote the fusion of medical technology and humanistic spirit; to standardize the medical behaviors with medical ethics, guide medical practice with humanities quality, create a comfortable and harmonious medical environment, namely medical workers show the reverence for life; In medical practice, should promote " humanistic spirit" , remember " patients interest first" ; further carry forward the " humanistic care" and offer sincere love to patients.%目前,医务人员医学人文品格中的伦理性缺失表现为医患关系冷漠、医患沟通不畅等.加强医务人员人文品格的培养,其途径在于弘扬人文精神,注重医务工作者人文品格的培养,促进医疗技术与人文精神的融合;用医学伦理规范医疗行为,用人文品格指导医疗实践活动,努力营造宽松、和谐的医疗环境,即医务工作者要敬畏人的生命;医疗活动中,要倡导“人本精神”,牢记“患者利益至上”;进一步弘扬“人文关怀”,奉献真诚爱心.

  12. Lower Limb Wearable Capacitive Sensing and Its Applications to Recognizing Human Gaits

    Directory of Open Access Journals (Sweden)

    Qining Wang

    2013-10-01

    Full Text Available In this paper, we present an approach to sense human body capacitance and apply it to recognize lower limb locomotion modes. The proposed wearable sensing system includes sensing bands, a signal processing circuit and a gait event detection module. Experiments on long-term working stability, adaptability to disturbance and locomotion mode recognition are carried out to validate the effectiveness of the proposed approach. Twelve able-bodied subjects are recruited, and eleven normal gait modes are investigated. With an event-dependent linear discriminant analysis classifier and feature selection procedure, four time-domain features are used for pattern recognition and satisfactory recognition accuracies (97:3% ± 0:5%, 97:0% ± 0:4%, 95:6% ± 0:9% and 97:0% ± 0:4% for four phases of one gait cycle respectively are obtained. The accuracies are comparable with that from electromyography-based systems and inertial-based systems. The results validate the effectiveness of the proposed lower limb capacitive sensing approach in recognizing human normal gaits.

  13. [Kairos. Decision-making in medical ethics].

    Science.gov (United States)

    Jousset, David

    2014-06-01

    This paper assesses the decision making patterns in medical ethics: the formalized pattern of decision science, the meditative pattern of an art of judgement and lastly the still-to-be-elaborated pattern of kairology or sense of the right time. The ethical decision is to be thought out in the conditions of medical action while resorting to the philosophical concepts that shed light on the issue. And it is precisely where medicine and philosophy of human action meet that the Greek notion of kairos, or "propitious moment", evokes the critical point where decision has to do with what is vital. Reflection shows that this kairos can be thought out outside the sacrificial pattern (deciding comes down to killing a possibility) by understanding the opportune moment as a sign of ethical action, as the condition for the formation of the subject (making a decision) and finally as a new relationship to time, including in the context of medical urgency. Thus with an approach to clinical ethics centred on the relation to the individual, the focus is less on the probabilistic knowledge of the decidable than on the meaning of the decision, and the undecidable comes to be accepted as an infinite dimension going beyond the limits of our acts, which makes the contingency and the grandeur of human responsibility.

  14. [Humans or material? Three levels of the discourse about the stem cell research from theological-ethical view].

    Science.gov (United States)

    Ernst, Stephan

    2004-01-01

    In the debate on the ethical evaluation of the stem cell research three levels can be differentiated. The first level of argumentation is that of weighing up goods: The possible therapeutical success for thousands of humans seems to justify the consumption of a few embryos. It is show, that this, however, already presupposes - on a second argumentation level - a judgement on the moral status of the embryo. Different moments of time, when human dignity and life protection are ascribe to the embryo, have already been discussed, but in spite of all rationality of the arguments a consensus has not been reached. On this third level of argumentation two fundamental meanings of reality can be differentiated. The empirical-observing and the communicative-participating view. These lead to a different moral evaluation of the embryo. This contribution votes for the priority of the communicative-participating view. It receives addition support by theology and Christian faith.

  15. On Marxism Humanity Dimension in the Picture of Administrative Ethics%行政伦理学图景中的马克思主义人学向度

    Institute of Scientific and Technical Information of China (English)

    年勇

    2011-01-01

    行政人的伦理道德问题是行政伦理学所要探寻的主要问题,而"现实的人"及其存在方式是理解行政伦理学的前提。马克思主义人学是关于人的科学理论,它从人的存在、人的本质、人的地位、人的价值以及人的发展等多个角度为理解行政领域中的人提供了新的路数。以人学为向度的行政伦理学研究有助于理解马克思主义人学的科学内涵。%The moral and ethical issue of administrative personnel is the major issues that administrative ethics explores but "real people" and their existence way is the premise of understand administrative ethics.Marxism humanity is scientific theory about the people.It provide a new large way to understand administrative areas people from its human existence,human nature,people's status,human values and human development.The study of administrative ethics from humanity dimensions can help people to understand the scientific connotation of Marxist humanity。

  16. Reproductive cloning in humans and therapeutic cloning in primates: is the ethical debate catching up with the recent scientific advances?

    Science.gov (United States)

    Camporesi, S; Bortolotti, L

    2008-09-01

    After years of failure, in November 2007 primate embryonic stem cells were derived by somatic cellular nuclear transfer, also known as therapeutic cloning. The first embryo transfer for human reproductive cloning purposes was also attempted in 2006, albeit with negative results. These two events force us to think carefully about the possibility of human cloning which is now much closer to becoming a reality. In this paper we tackle this issue from two sides, first summarising what scientists have achieved so far, then discussing some of the ethical arguments in favour and against human cloning which are debated in the context of policy making and public consultation. Therapeutic cloning as a means to improve and save lives has uncontroversial moral value. As to human reproductive cloning, we consider and assess some common objections and failing to see them as conclusive. We do recognise, though, that there will be problems at the level of policy and regulation that might either impair the implementation of human reproductive cloning or make its accessibility restricted in a way that could become difficult to justify on moral grounds. We suggest using the time still available before human reproductive cloning is attempted successfully to create policies and institutions that can offer clear directives on its legitimate applications on the basis of solid arguments, coherent moral principles, and extensive public consultation.

  17. Machine medical ethics

    CERN Document Server

    Pontier, Matthijs

    2015-01-01

    The essays in this book, written by researchers from both humanities and sciences, describe various theoretical and experimental approaches to adding medical ethics to a machine in medical settings. Medical machines are in close proximity with human beings, and getting closer: with patients who are in vulnerable states of health, who have disabilities of various kinds, with the very young or very old, and with medical professionals. In such contexts, machines are undertaking important medical tasks that require emotional sensitivity, knowledge of medical codes, human dignity, and privacy. As machine technology advances, ethical concerns become more urgent: should medical machines be programmed to follow a code of medical ethics? What theory or theories should constrain medical machine conduct? What design features are required? Should machines share responsibility with humans for the ethical consequences of medical actions? How ought clinical relationships involving machines to be modeled? Is a capacity for e...

  18. Ethical decision making in the conduct of research: role of individual, contextual and organizational factors. Commentary on "Science, human nature, and a new paradigm for ethics education".

    Science.gov (United States)

    Langlais, Philip J

    2012-09-01

    Despite the importance of scientific integrity to the well-being of society, recent findings suggest that training and mentoring in the responsible conduct of research are not very reliable or effective inhibitors of research misbehavior. Understanding how and why individual scientists decide to behave in ways that conform to or violate norms and standards of research is essential to the development of more effective training programs and the creation of more supportive environments. Scholars in business management, psychology, and other disciplines have identified many important factors that affect ethical behavior, including individual, contextual, and organizational factors. Surprisingly little research has been conducted to examine the role of these factors in either the development of ethical decision-making skills, or their applicability to ethical issues commonly encountered in research and other scholarly and professional activities. Interdisciplinary approaches combined with research and discipline relevant paradigms should greatly enhance understanding of the individual contextual and organizational factors involved in ethical and unethical research conduct. Such studies will inform and facilitate the development of more effective ethics education programs in the sciences and engineering professions.

  19. Business ethics

    OpenAIRE

    Duong, Thi

    2002-01-01

    The goal of this paper is to present examples of business ethics issues. What is business ethics, things concerned in this field are and why it is needed and important when doing business? The concept of business ethics has connotations to provision, rules and standards in directing the behavior of actors in the business. Business ethics involves compliance with the law, the implementation of ethical responsibilities of a business, the protection of the rights of those who are related to the ...

  20. Age-related changes in the joint position sense of the human hand

    Directory of Open Access Journals (Sweden)

    Kalisch T

    2012-11-01

    Full Text Available Tobias Kalisch,1,2,* Jan-Christoph Kattenstroth,2,* Rebecca Kowalewski,2 Martin Tegenthoff,1 Hubert R Dinse21Department of Neurology, BG-Kliniken Bergmannsheil, Ruhr-University Bochum, Bochum, Germany; 2Neural Plasticity Lab, Institute for Neuroinformatics, Ruhr-University Bochum, Bochum, Germany*These authors contributed equally to this workAbstract: Age-related changes in lower limb joint position sense and their contributions to postural stability are well documented. In contrast, only a few studies have investigated the effect of age on proprioceptive hand function. Here, we introduce a novel test for measuring joint position sense in the fingers of the human hand. In a concurrent matching task, subjects had to detect volume differences between polystyrene balls grasped with their dominant (seven test stimuli: 126–505 cm3 and their nondominant hand (three reference stimuli: 210, 294, and 505 cm3. A total of 21 comparisons were performed to assess the number of errors, the weight of errors (ie, the volume difference between test and reference stimuli, and the direction of errors (ie, over- or underestimation of test stimulus. The test was applied to 45 healthy subjects aged 21 to 79 years. Our results revealed that all variables changed significantly with age, with the number of errors showing the strongest increase. We also assessed tactile acuity (two-point discrimination thresholds and sensorimotor performance (pegboard performance in a subset of subjects, but these scores did not correlate with joint position sense performance, indicating that the test reveals specific information about joint position sense that is not captured with pure sensory or motor tests. The average test–retest reliability assessed on 3 consecutive days was 0.8 (Cronbach's alpha. Our results demonstrate that this novel test reveals age-related decline in joint position sense acuity that is independent from sensorimotor performance.Keywords: aging, hand

  1. [Ethical dilemmas in health].

    Science.gov (United States)

    Boléo-Tomé, J

    2009-01-01

    It is difficult to speak of ethic dilemmas in a society that has relativism as the oficial philosophical and political doctrine, i.e., stable values and behavior references, are denied, both in health care and in any other area of human knowledge. In the field of medical sciences it is even pretended to pass from the observational methodology to a field of manipulation and manipulability. It is the very Ethic that is presented as a dilemma. In these conditions one needs to know the lines of thought that are defended, to replace and make disappear the stable ethic references: ecletism, historicism, scientificism, pragmatism, and nihilism itself, that lead to the 'new ethic paradigm', that has created by itself a pseudo-spirituality. The truth is we are adrift in the 'Ethic of Convenience' which changes according to the majorities. In this setting the way to go is to rediscover the abandoned ethic values: only with an objective ethic, with sound references and foundations, it is possible to re-establish and perfect the patient-physician relationship, for a better social health. And this begins with the ethic problem of human life.

  2. Improving Trend of Adhering to Ethical Measures in Iranian Research in Human Genetics: A Survey from 2005 to 2009; and the Road Ahead.

    Directory of Open Access Journals (Sweden)

    Seyed Hasan Saadat

    2013-10-01

    Full Text Available The overwhelming rate of progress in biotechnological research especially in human genetics, as well as the high levels of power these researches provide us to intervene in human lives, brings serious concerns on the ethical problems that may rise from these research endeavors. To address this critical issue in Iran, we conducted a study issuing publishing authors of studies in human genetics from Iran, between years 2005 to 2011.We contacted 116 corresponding authors of articles issuing genetics research on human subjects, asking them that whether they have gotten either informed consent from their study subjects or ethical approval from their institutional ethics committee.Only 13% of the authors presented both documents; 52% had not gotten any of the documents; 19% of authors felt no need for getting the mentioned documents; 13% declared that they only gotten oral consent and 3% of authors did not remember whether they have gotten any documentation or not.The trend for informed consent taking was improving over time, from 5% in year 2006 to 24% in 2009. The result was not satisfactory but showed good trend towards improvement, recommending more serious follow up concerning ethical aspects of articles published in human genetics.

  3. Work ethics and general work attitudes in adolescents are related to quality of life, sense of coherence and subjective health – a Swedish questionnaire study

    Directory of Open Access Journals (Sweden)

    Håkansson Anders

    2005-10-01

    Full Text Available Abstract Background Working life is an important arena in most people's lives, and the working line concept is important for the development of welfare in a society. For young people, the period before permanent establishment in working life has become longer during the last two decades. Knowledge about attitudes towards work can help us to understand young people's transition to the labour market. Adolescents are the future workforce, so it seems especially important to notice their attitudes towards work, including attitudes towards the welfare system. The aim of this study was to describe and analyse upper secondary school students' work attitudes, and to explore factors related to these attitudes. Methods The sample consisted of 606 upper secondary school students. They all received a questionnaire including questions about quality of life (QOL, sense of coherence (SOC, subjective health and attitudes towards work. The response rate was 91%. A factor analysis established two dimensions of work attitudes. Multivariate analyses were carried out by means of logistic regression models. Results Work ethics (WE and general work attitudes (GWA were found to be two separate dimensions of attitudes towards work. Concerning WE the picture was similar regardless of gender or study programme. Males in theoretical programmes appeared to have more unfavourable GWA than others. Multivariate analyses revealed that good QOL, high SOC and good health were significantly related to positive WE, and high SOC was positively related to GWA. Being female was positively connected to WE and GWA, while studying on a practical programme was positively related to GWA only. Among those who received good parental support, GWA seemed more favourable. Conclusion Assuming that attitudes towards work are important to the working line concept, this study points out positive factors of importance for the future welfare of the society. Individual factors such as female gender

  4. The human security approach as a frame for considering ethics of global environmental change

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2010-01-01

    textabstractWe need languages for transition; a human security framework adds value to languages of human rights, human development, and global public goods, through its emphases on interconnectedness and solidarity.

  5. Neuroethics: the pursuit of transforming medical ethics in scientific ethics.

    Science.gov (United States)

    Figueroa, Gustavo

    2016-02-20

    Ethical problems resulting from brain research have given rise to a new discipline termed neuroethics, representing a new kind of knowledge capable of discovering the neural basis for universal ethics. The article (1) tries to evaluate the contributions of neuroethics to medical ethics and its suitability to outline the foundations of universal ethics, (2) critically analyses the process of founding this universal ethic. The potential benefits of applying neuroimaging, psychopharmacology and neurotechnology have to be carefully weighed against their potential harm. In view of these questions, an intensive dialogue between neuroscience and the humanities is more necessary than ever.

  6. The ethics of information

    CERN Document Server

    Floridi, Luciano

    2013-01-01

    Luciano Floridi develops an original ethical framework for dealing with the new challenges posed by Information and Communication Technologies (ICTs). ICTs have profoundly changed many aspects of life, including the nature of entertainment, work, communication, education, health care, industrial production and business, social relations, and conflicts. They have had a radical and widespread impact on our moral lives and on contemporary ethical debates. Privacy, ownership, freedom of speech, responsibility, technological determinism, the digital divide, and pornography online are only some of the pressing issues that characterise the ethical discourse in the information society. They are the subject of Information Ethics (IE), the new philosophical area of research that investigates the ethical impact of ICTs on human life and society. Since the seventies, IE has been a standard topic in many curricula. In recent years, there has been a flourishing of new university courses, international conferences, workshop...

  7. Code of ethics and ethical dilemmas' management in health professions

    Directory of Open Access Journals (Sweden)

    Sofia Triadafyllidou

    2011-10-01

    Full Text Available As the main interest of health professionals is for the well-being of patients/clients, ethical decision making is one of the prominent elements of his/her professionalism. Aim: The present study aims to illustrate the role of ethical judgment and the so-called "moral imagination" in health professions. Method and material: Review of theoretical and research literature, including both classic and recent sources about ethical dilemmas that health professionals may anticipate, as well as the suggested ways to manage these dilemmas. Results: Health professionals often have to act in complicated situations. Review of relevant literature indicates that the professionals' ethical decisions are structured not only through the codes of ethics, but also through other collective practices, such as organizational culture and cultural schemas about the role of health professional. Resorting to schematic thinking may temporarily release the professional from his/her concerns, but in the long run, it may devoid him/her of the sense of satisfaction from work and of the ability to offer clients the optimal care. The development of the so-called "moral imagination" permits the professional to advance from the typical application of the rules to actual ethical judgment. Conclusions: Ethical decision making presupposes not only a thorough knowledge of ethical guidelines, but also the development of the ability to openly reflect upon the ethical dimensions of an issue (moral imagination that allows health professionals to overcome schematic thinking and investigate comprehensive solutions to ethical dilemmas.

  8. From deep-sea volcanoes to human pathogens: a conserved quorum-sensing signal in Epsilonproteobacteria.

    Science.gov (United States)

    Pérez-Rodríguez, Ileana; Bolognini, Marie; Ricci, Jessica; Bini, Elisabetta; Vetriani, Costantino

    2015-05-01

    Chemosynthetic Epsilonproteobacteria from deep-sea hydrothermal vents colonize substrates exposed to steep thermal and redox gradients. In many bacteria, substrate attachment, biofilm formation, expression of virulence genes and host colonization are partly controlled via a cell density-dependent mechanism involving signal molecules, known as quorum sensing. Within the Epsilonproteobacteria, quorum sensing has been investigated only in human pathogens that use the luxS/autoinducer-2 (AI-2) mechanism to control the expression of some of these functions. In this study we showed that luxS is conserved in Epsilonproteobacteria and that pathogenic and mesophilic members of this class inherited this gene from a thermophilic ancestor. Furthermore, we provide evidence that the luxS gene is expressed--and a quorum-sensing signal is produced--during growth of Sulfurovum lithotrophicum and Caminibacter mediatlanticus, two Epsilonproteobacteria from deep-sea hydrothermal vents. Finally, we detected luxS transcripts in Epsilonproteobacteria-dominated biofilm communities collected from deep-sea hydrothermal vents. Taken together, our findings indicate that the epsiloproteobacterial lineage of the LuxS enzyme originated in high-temperature geothermal environments and that, in vent Epsilonproteobacteria, luxS expression is linked to the production of AI-2 signals, which are likely produced in situ at deep-sea vents. We conclude that the luxS gene is part of the ancestral epsilonproteobacterial genome and represents an evolutionary link that connects thermophiles to human pathogens.

  9. Assessment of human respiration patterns via noncontact sensing using Doppler multi-radar system.

    Science.gov (United States)

    Gu, Changzhan; Li, Changzhi

    2015-03-16

    Human respiratory patterns at chest and abdomen are associated with both physical and emotional states. Accurate measurement of the respiratory patterns provides an approach to assess and analyze the physical and emotional states of the subject persons. Not many research efforts have been made to wirelessly assess different respiration patterns, largely due to the inaccuracy of the conventional continuous-wave radar sensor to track the original signal pattern of slow respiratory movements. This paper presents the accurate assessment of different respiratory patterns based on noncontact Doppler radar sensing. This paper evaluates the feasibility of accurately monitoring different human respiration patterns via noncontact radar sensing. A 2.4 GHz DC coupled multi-radar system was used for accurate measurement of the complete respiration patterns without any signal distortion. Experiments were carried out in the lab environment to measure the different respiration patterns when the subject person performed natural breathing, chest breathing and diaphragmatic breathing. The experimental results showed that accurate assessment of different respiration patterns is feasible using the proposed noncontact radar sensing technique.

  10. The Budapest Meeting 2005. Intensified networking on ethics of science : The case of reproductive cloning, germline gene therapy and human dignity

    NARCIS (Netherlands)

    van Steendam, Guido; Dinnyes, Andras; Mallet, Jacques; Roosendaal, Hans E.

    2006-01-01

    This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy.

  11. The Budapest Meeting 2005. Intensified networking on ethics of science : The case of reproductive cloning, germline gene therapy and human dignity

    NARCIS (Netherlands)

    Steendam, van Guido; Dinnyes, Andras; Mallet, Jacques; Roosendaal, Hans E.

    2006-01-01

    This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Dis

  12. The Budapest Meeting 2005. Intensified networking on ethics of science : The case of reproductive cloning, germline gene therapy and human dignity

    NARCIS (Netherlands)

    van Steendam, Guido; Dinnyes, Andras; Mallet, Jacques; Roosendaal, Hans E.

    2006-01-01

    This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6–9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Dis

  13. Professional virtue and professional self-awareness: a case study in engineering ethics.

    Science.gov (United States)

    Stovall, Preston

    2011-03-01

    This paper articulates an Aristotelian theory of professional virtue and provides an application of that theory to the subject of engineering ethics. The leading idea is that Aristotle's analysis of the definitive function of human beings, and of the virtues humans require to fulfill that function, can serve as a model for an analysis of the definitive function or social role of a profession and thus of the virtues professionals must exhibit to fulfill that role. Special attention is given to a virtue of professional self-awareness, an analogue to Aristotle's phronesis or practical wisdom. In the course of laying out my account I argue that the virtuous professional is the successful professional, just as the virtuous life is the happy life for Aristotle. I close by suggesting that a virtue ethics approach toward professional ethics can enrich the pedagogy of professional ethics courses and help foster a sense of pride and responsibility in young professionals.

  14. Fabrication of Anti-human Cardiac Troponin I Immunogold Nanorods for Sensing Acute Myocardial Damage

    Science.gov (United States)

    Guo, Z. R.; Gu, C. R.; Fan, X.; Bian, Z. P.; Wu, H. F.; Yang, D.; Gu, N.; Zhang, J. N.

    2009-12-01

    A facile, rapid, solution-phase method of detecting human cardiac troponin I for sensing myocardial damage has been described using gold nanorods-based biosensors. The sensing is demonstrated by the distinct change of the longitudinal surface plasmon resonance wavelength of the gold nanorods to specific antibody-antigen binding events. For a higher sensitivity, the aspect ratio of gold nanorods is increased up to ca 5.5 by simply adding small amount of HCl in seed-mediated growth solution. Experimental results show that the detecting limit of the present method is 10 ng/mL. Contrast tests reveal that these gold nanorods-based plasmonic biosensors hold much higher sensitivity than that of conventionally spherical gold nanoparticles.

  15. Fabrication of Anti-human Cardiac Troponin I Immunogold Nanorods for Sensing Acute Myocardial Damage

    Directory of Open Access Journals (Sweden)

    Fan X

    2009-01-01

    Full Text Available Abstract A facile, rapid, solution-phase method of detecting human cardiac troponin I for sensing myocardial damage has been described using gold nanorods-based biosensors. The sensing is demonstrated by the distinct change of the longitudinal surface plasmon resonance wavelength of the gold nanorods to specific antibody–antigen binding events. For a higher sensitivity, the aspect ratio of gold nanorods is increased up to ca 5.5 by simply adding small amount of HCl in seed-mediated growth solution. Experimental results show that the detecting limit of the present method is 10 ng/mL. Contrast tests reveal that these gold nanorods-based plasmonic biosensors hold much higher sensitivity than that of conventionally spherical gold nanoparticles.

  16. Reflexiones sobre ética de investigación en seres humanos Reflections about research ethics in humans

    Directory of Open Access Journals (Sweden)

    Alberto Perales

    2010-09-01

    Full Text Available Con el objetivo de plantear la necesaria reflexión moral sobre la responsabilidad personal que asume cada investigador cuando realiza investigación científica en seres humanos, se presenta un ensayo de temática científica y moral, utilizando información de la literatura científica y ética pertinentes. En torno a los conceptos de ética heterónoma y ética autónoma, se plantea que, en última instancia y allende el consentimiento Informado y los cursos de adiestramiento sobre ética en investigación, la conducta del/de la investigador/a dependerá de su propia responsabilidad moral puesta a prueba en diversos contextos situacionales. Se utilizan dos modelos explicativos para comprender esta dinámica, el de normalidad en salud mental y el del desarrollo moral del hombre. Se concluye que el proceso de investigación en seres humanos constituye una actividad científica y moral que, dependiendo de diversas situaciones de conflicto de interés, pondrá siempre a prueba los controles morales del investigador.In order to propose the necessary moral reflection about the personal responsibility that each researcher assumes when he performs scientific research in human beings, an essay of moral and scientific themes is presented, using information from the relevant scientific and ethical literature. Around the concepts of heteronomous and autonomous ethics, it is proposed that ultimately and beyond informed consent and training courses on research ethics, the behavior of the researcher will depend on his/her own moral responsibility, tested in different situational contexts. Two explanatory models are used in order to understand this dynamic, the one of normality in mental health and the one of moral development of men. We conclude that the research process in human beings is a scientific and moral activity that, depending in various situations of conflicts of interest, will always test the researcher’s moral controls.

  17. Virtuous acts as practical medical ethics: an empirical study.

    Science.gov (United States)

    Little, Miles; Gordon, Jill; Markham, Pippa; Rychetnik, Lucie; Kerridge, Ian

    2011-10-01

    To examine the nature, scope and significance of virtues in the biographies of medical practitioners and to determine what kind of virtues are at play in their ethical behaviour and reflection. A case study involving 19 medical practitioners associated with the Sydney Medical School, using semi-structured narrative interviews. Narrative data were analysed using dialectical empiricism, constant comparison and iterative reformulation of research questions. Participants represented virtuous acts as centrally important in their moral assessments of both themselves and others. Acts appeared to be contextually virtuous, rather than expressions of stable character traits, and virtue was linked to acts that served to protect or enhance fundamental values attached to ontological security and human flourishing. Virtue ethics, in this sense, was the single most important ethical system for each of the participants. Virtue ethics, construed as the appraisal of acts in contexts of risk, danger or threat to foundational values, emerged as the 'natural' ethical approach for medical practitioners in this case study. Teaching medical ethics to students and graduates alike needs to accommodate the priority attached to virtuous acts. © 2011 Blackwell Publishing Ltd.

  18. Information technology and ethics: An exploratory factor analysis

    Energy Technology Data Exchange (ETDEWEB)

    Conger, S. [Southern Methodist Univ., Dallas, TX (United States); Loch, K.D. [Georgia State Univ., Atlanta, GA (United States); Helft, B.L. [Baruch College, New York, NY (United States)

    1994-12-31

    Ethical dilemmas are situations in which a decision results in unpleasant consequences. The unpleasant consequences are treated as a zero-sum game in which someone always loses. Introducing information technology (IT) to a situation makes the recognition of a potential loser more abstract and difficult to identify, thus an ethical dilemma may go unrecognized. The computer mediates the human relationship which causes a lost sense of contact with a person at the other end of the computer connection. In 1986, Richard O. Mason published an essay identifying privacy, accuracy, property, and Access (PAPA) as the four main ethical issues of the information age. Anecdotes for each issue describe the injured party`s perspective to identify consequences resulting from unethical use of information and information technology. This research sought to validate Mason`s social issues empirically, but with distinct differences. Mason defined issues to raise awareness and initiate debate on the need for a social agenda; our focus is on individual computer users and the attitudes they hold about ethical behavior in computer use. This study examined the attitudes of the computer user who experiences the ethical dilemma to determine the extent to which ethical components are recognized, and whether Mason`s issues form recognizable constructs.

  19. Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation

    Science.gov (United States)

    Scotti, John S.; Leung, Ivanhoe K. H.; Ge, Wei; Bentley, Michael A.; Paps, Jordi; Kramer, Holger B.; Lee, Joongoo; Aik, WeiShen; Choi, Hwanho; Paulsen, Steinar M.; Bowman, Lesley A. H.; Loik, Nikita D.; Horita, Shoichiro; Ho, Chia-hua; Kershaw, Nadia J.; Tang, Christoph M.; Claridge, Timothy D. W.; Preston, Gail M.; McDonough, Michael A.; Schofield, Christopher J.

    2014-01-01

    The roles of 2-oxoglutarate (2OG)-dependent prolyl-hydroxylases in eukaryotes include collagen stabilization, hypoxia sensing, and translational regulation. The hypoxia-inducible factor (HIF) sensing system is conserved in animals, but not in other organisms. However, bioinformatics imply that 2OG-dependent prolyl-hydroxylases (PHDs) homologous to those acting as sensing components for the HIF system in animals occur in prokaryotes. We report cellular, biochemical, and crystallographic analyses revealing that Pseudomonas prolyl-hydroxylase domain containing protein (PPHD) contain a 2OG oxygenase related in structure and function to the animal PHDs. A Pseudomonas aeruginosa PPHD knockout mutant displays impaired growth in the presence of iron chelators and increased production of the virulence factor pyocyanin. We identify elongation factor Tu (EF-Tu) as a PPHD substrate, which undergoes prolyl-4-hydroxylation on its switch I loop. A crystal structure of PPHD reveals striking similarity to human PHD2 and a Chlamydomonas reinhardtii prolyl-4-hydroxylase. A crystal structure of PPHD complexed with intact EF-Tu reveals that major conformational changes occur in both PPHD and EF-Tu, including a >20-Å movement of the EF-Tu switch I loop. Comparison of the PPHD structures with those of HIF and collagen PHDs reveals conservation in substrate recognition despite diverse biological roles and origins. The observed changes will be useful in designing new types of 2OG oxygenase inhibitors based on various conformational states, rather than active site iron chelators, which make up most reported 2OG oxygenase inhibitors. Structurally informed phylogenetic analyses suggest that the role of prolyl-hydroxylation in human hypoxia sensing has ancient origins. PMID:25197067

  20. Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation.

    Science.gov (United States)

    Scotti, John S; Leung, Ivanhoe K H; Ge, Wei; Bentley, Michael A; Paps, Jordi; Kramer, Holger B; Lee, Joongoo; Aik, WeiShen; Choi, Hwanho; Paulsen, Steinar M; Bowman, Lesley A H; Loik, Nikita D; Horita, Shoichiro; Ho, Chia-hua; Kershaw, Nadia J; Tang, Christoph M; Claridge, Timothy D W; Preston, Gail M; McDonough, Michael A; Schofield, Christopher J

    2014-09-16

    The roles of 2-oxoglutarate (2OG)-dependent prolyl-hydroxylases in eukaryotes include collagen stabilization, hypoxia sensing, and translational regulation. The hypoxia-inducible factor (HIF) sensing system is conserved in animals, but not in other organisms. However, bioinformatics imply that 2OG-dependent prolyl-hydroxylases (PHDs) homologous to those acting as sensing components for the HIF system in animals occur in prokaryotes. We report cellular, biochemical, and crystallographic analyses revealing that Pseudomonas prolyl-hydroxylase domain containing protein (PPHD) contain a 2OG oxygenase related in structure and function to the animal PHDs. A Pseudomonas aeruginosa PPHD knockout mutant displays impaired growth in the presence of iron chelators and increased production of the virulence factor pyocyanin. We identify elongation factor Tu (EF-Tu) as a PPHD substrate, which undergoes prolyl-4-hydroxylation on its switch I loop. A crystal structure of PPHD reveals striking similarity to human PHD2 and a Chlamydomonas reinhardtii prolyl-4-hydroxylase. A crystal structure of PPHD complexed with intact EF-Tu reveals that major conformational changes occur in both PPHD and EF-Tu, including a >20-Å movement of the EF-Tu switch I loop. Comparison of the PPHD structures with those of HIF and collagen PHDs reveals conservation in substrate recognition despite diverse biological roles and origins. The observed changes will be useful in designing new types of 2OG oxygenase inhibitors based on various conformational states, rather than active site iron chelators, which make up most reported 2OG oxygenase inhibitors. Structurally informed phylogenetic analyses suggest that the role of prolyl-hydroxylation in human hypoxia sensing has ancient origins.

  1. The Budapest Meeting 2005 intensified networking on ethics of science: the case of reproductive cloning, germline gene therapy and human dignity.

    Science.gov (United States)

    Van Steendam, Guido; Dinnyés, András; Mallet, Jacques; Meloni, Rolando; Casabona, Carlos Romeo; González, Jorge Guerra; Kure, Josef; Szathmáry, Eörs; Vorstenbosch, Jan; Molnár, Péter; Edbrooke, David; Sándor, Judit; Oberfrank, Ferenc; Cole-Turner, Ron; Hargittai, István; Littig, Beate; Ladikas, Miltos; Mordini, Emilio; Roosendaal, Hans E; Salvi, Maurizio; Gulyás, Balázs; Malpede, Diana

    2006-10-01

    This paper reports on the meeting of the Sounding Board of the EU Reprogenetics Project that was held in Budapest, Hungary, 6-9 November 2005. The Reprogenetics Project runs from 2004 until 2007 and has a brief to study the ethical aspects of human reproductive cloning and germline gene therapy. Discussions during The Budapest Meeting are reported in depth in this paper as well as the initiatives to involve the participating groups and others in ongoing collaborations with the goal of forming an integrated network of European resources in the fields of ethics of science.

  2. Perspectives on Applied Ethics

    OpenAIRE

    2007-01-01

    Applied ethics is a growing, interdisciplinary field dealing with ethical problems in different areas of society. It includes for instance social and political ethics, computer ethics, medical ethics, bioethics, envi-ronmental ethics, business ethics, and it also relates to different forms of professional ethics. From the perspective of ethics, applied ethics is a specialisation in one area of ethics. From the perspective of social practice applying eth-ics is to focus on ethical aspects and ...

  3. Endobiont viruses sensed by the human host - beyond conventional antiparasitic therapy.

    Directory of Open Access Journals (Sweden)

    Raina N Fichorova

    Full Text Available Wide-spread protozoan parasites carry endosymbiotic dsRNA viruses with uncharted implications to the human host. Among them, Trichomonas vaginalis, a parasite adapted to the human genitourinary tract, infects globally ∼250 million each year rendering them more susceptible to devastating pregnancy complications (especially preterm birth, HIV infection and HPV-related cancer. While first-line antibiotic treatment (metronidazole commonly kills the protozoan pathogen, it fails to improve reproductive outcome. We show that endosymbiotic Trichomonasvirus, highly prevalent in T. vaginalis clinical isolates, is sensed by the human epithelial cells via Toll-like receptor 3, triggering Interferon Regulating Factor -3, interferon type I and proinflammatory cascades previously implicated in preterm birth and HIV-1 susceptibility. Metronidazole treatment amplified these proinflammatory responses. Thus, a new paradigm targeting the protozoan viruses along with the protozoan host may prevent trichomoniasis-attributable inflammatory sequelae.

  4. The Ethics of Exploitation

    Directory of Open Access Journals (Sweden)

    Paul McLaughlin

    2008-11-01

    Full Text Available Philosophical inquiry into exploitation has two major deficiencies to date: it assumes that exploitation is wrong by definition; and it pays too much attention to the Marxian account of exploitation. Two senses of exploitation should be distinguished: the ‘moral’ or pejorative sense and the ‘non-moral’ or ‘non-prejudicial’ sense. By demonstrating the conceptual inadequacy of exploitation as defined in the first sense, and by defining exploitation adequately in the latter sense, we seek to demonstrate the moral complexity of exploitation. We contend, moreover, that moral evaluation of exploitation is only possible once we abandon a strictly Marxian framework and attempt, in the long run, to develop an integral ethic along Godwinian lines.

  5. Emotions, narratives, and ethical mindfulness.

    Science.gov (United States)

    Guillemin, Marilys; Gillam, Lynn

    2015-06-01

    Clinical care is laden with emotions, from the perspectives of both clinicians and patients. It is important that emotions are addressed in health professions curricula to ensure that clinicians are humane healers as well as technical experts. Emotions have a valuable and generative role in health professional ethics education.The authors have previously described a narrative ethics pedagogy, the aim of which is to develop ethical mindfulness. Ethical mindfulness is a state of being that acknowledges everyday ethics and ethically important moments as significant in clinical care, with the aim of enabling ethical clinical practice. Using a sample narrative, the authors extend this concept to examine five features of ethical mindfulness as they relate to emotions: (1) being sensitized to emotions in everyday practice, (2) acknowledging and understanding the ways in which emotions are significant in practice, (3) being able to articulate the emotions at play during ethically important moments, (4) being reflexive and acknowledging both the generative aspects and the limitations of emotions, and (5) being courageous.The process of writing and engaging with narratives can lead to ethical mindfulness, including the capacity to understand and work with emotions. Strategies for productively incorporating emotions in narrative ethics teaching are described. This can be a challenging domain within medical education for both educators and health care students and thus needs to be addressed sensitively and responsibly. The potential benefit of educating health professionals in a way which addresses emotionality in an ethical framework makes the challenges worthwhile.

  6. Ethical Revision.

    Science.gov (United States)

    Jackman, Mary Kathryn

    1994-01-01

    Discusses the dilemma of how to respond to student papers advancing morally repugnant positions. Advocates conceptualizing writing as an ethical act and connecting ethics and revision. Describes briefly how three such student papers were handled. (SR)

  7. Ethical decision-making: the doctrine of sin and grace

    Directory of Open Access Journals (Sweden)

    S. P. Giles

    2009-07-01

    Full Text Available Ethical decision-making presupposes the possession of a free will. Central to a discussion on reformed ethics is the question of the bounds of freedom of the will. The reformed tradition, along with the wider Christian tradition, affirms that the will is not free in the Pelagian sense of being absolutely free, but is constrained by the effects of humanity’s fall from original righteousness. This ariticle considers the nature and extent to which the will is considered free, or no longer free at all. The question posed here, within the reformed theoretic ethical framework, is whether the will is so vitiated that a person is in- capable of any effective choice of action or inaction in the face of any moral dilemma, or does fallen humanity still possess some ability to make a free choice, albeit under conditions of impaired freedom of the will?

  8. Policy Writing as Dialogue: Drafting an Aboriginal Chapter for Canada's Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans

    Directory of Open Access Journals (Sweden)

    Jeff Reading

    2010-07-01

    Full Text Available Writing policy that applies to First Nations, Inuit and Métis peoples in Canada has become more interactive as communities and their representative organizations press for practical recognition of an Aboriginal right of self-determination. When the policy in development is aimed at supporting “respect for human dignity” as it is in the case of ethics of research involving humans, the necessity of engaging the affected population becomes central to the undertaking.

  9. Ethics in research with human beings: some issues about Psychology Ética em pesquisa com seres humanos: alguns tópicos sobre a psicologia

    Directory of Open Access Journals (Sweden)

    Sílvia Helena Koller

    2008-04-01

    Full Text Available This paper examines some ethical issues in research with human beings, especially addressing the area of Psychology, such as the use of ethical codes; minimum risk; informed consent; debriefing; confidentiality; and ethical committees. It suggests ways for researchers to increase understanding and the proper use of the ethical codes, to guarantee their own protection, and to avoid abuses of power. Special attention is given to methodological issues related to ethics.Este artigo examina alguns aspectos éticos em pesquisa com seres humanos, especialmente endereçando a área da Psicologia, tais como o uso de resoluções éticas; risco mínimo; consentimento livre e esclarecido; decepção; confidencialidade e atuação de comitês de ética. Sugere caminhos aos pesquisadores para incrementar o entendimento e o uso apropriado de códigos de ética, para garantir sua própria proteção e evitar abuso de poder. Atenção especial é dada a assuntos metodológicos relacionados à ética.

  10. Project ethics

    CERN Document Server

    Jonasson, Haukur Ingi

    2013-01-01

    How relevant is ethics to project management? The book - which aims to demystify the field of ethics for project managers and managers in general - takes both a critical and a practical look at project management in terms of success criteria, and ethical opportunities and risks. The goal is to help the reader to use ethical theory to further identify opportunities and risks within their projects and thereby to advance more directly along the path of mature and sustainable managerial practice.

  11. Current outlook of ethics in research with human subjects Panorama atual da ética em pesquisa em seres humanos

    Directory of Open Access Journals (Sweden)

    Marystella Tomoe Takahashi

    2011-04-01

    Full Text Available In the last decades, medical care has been increasingly permeated by the concept of evidence-based-medicine, in which clinical research plays a crucial role in establishing diagnostic and treatment. Following the improvements in clinical research, we have a growing concern and understanding that some ethical issues must be respected when the subjects are human beings. Research with human subjects relies on the principles of autonomy, beneficence, no maleficence and justice. Ordinance 196/96 from the National Health Board adds to the Brazilian legislation such renowned bioethical principles. AIM: Discuss the main ethical aspects involved in research with human subjects. MATERIALS AND METHODS: Critical analysis of Ordinance 196/96 and related literature. CONCLUSION: Ordinance 196/96 rules research with human subjects; nevertheless, it requires more in-depth discussions regarding the informed consent, use of placebo, research with vulnerable populations and research in developing countries.Nas últimas décadas, a medicina tem sido cada vez mais permeada pelo conceito de medicina baseada em evidências, na qual a pesquisa clínica possui papel crucial no estabelecimento de diretrizes diagnósticas e terapêuticas. Com o avanço da pesquisa clínica, surgiu a preocupação e o entendimento que certos padrões éticos devam ser obedecidos quando o objeto de estudo é o ser humano. A pesquisa em seres humanos baseia-se nos princípios da autonomia, beneficência, não maleficência e justiça. A Resolução 196/96 do Conselho Nacional de Saúde incorpora à legislação brasileira tais princípios bioéticos consagrados. OBJETIVO: Discutir os principais aspectos éticos envolvidos na pesquisa em seres humanos. MATERIAL E MÉTODO: Análise crítica da Resolução 196/96 do CNS e literatura correlata. CONCLUSÃO: A Resolução 196/96 do Conselho Nacional de Saúde regulamenta a experimentação em seres humanos, no entanto necessita de discussões mais

  12. Ethical Impotence

    Science.gov (United States)

    Sternberg, Robert J.

    2015-01-01

    Ethical impotence occurs when one wants to act ethically but feels powerless to do anything about the perceived unethical behavior. One may feel that one's actions will have no impact or that those actions actually will have harmful consequences to oneself and/or others. Ethical impotence can be understood in terms of an eight-step model of…

  13. Ethical leadership

    NARCIS (Netherlands)

    den Hartog, D.N.

    2015-01-01

    High-profile cases of leaders’ ethical failure in different settings and sectors have led to increased attention to ethical leadership in organizations. In this review, I discuss the rapidly developing field of ethical leadership from an organizational behavior/psychology perspective, taking a behav

  14. Human behavior understanding in networked sensing theory and applications of networks of sensors

    CERN Document Server

    Spagnolo, Paolo; Distante, Cosimo

    2014-01-01

    This unique text/reference provides a broad overview of both the technical challenges in sensor network development, and the real-world applications of distributed sensing. Important aspects of distributed computing in large-scale networked sensor systems are analyzed in the context of human behavior understanding, including such topics as systems design tools and techniques, in-network signals, and information processing. Additionally, the book examines a varied range of application scenarios, covering surveillance, indexing and retrieval, patient care, industrial safety, social and ambient

  15. What Role for Law, Human Rights, and Bioethics in an Age of Big Data, Consortia Science, and Consortia Ethics? The Importance of Trustworthiness

    Directory of Open Access Journals (Sweden)

    Edward S. Dove

    2015-08-01

    Full Text Available The global bioeconomy is generating new paradigm-shifting practices of knowledge co-production, such as collective innovation; large-scale, data-driven global consortia science (Big Science; and consortia ethics (Big Ethics. These bioeconomic and sociotechnical practices can be forces for progressive social change, but they can also raise predicaments at the interface of law, human rights, and bioethics. In this article, we examine one such double-edged practice: the growing, multivariate exploitation of Big Data in the health sector, particularly by the private sector. Commercial exploitation of health data for knowledge-based products is a key aspect of the bioeconomy and is also a topic of concern among publics around the world. It is exacerbated in the current age of globally interconnected consortia science and consortia ethics, which is characterized by accumulating epistemic proximity, diminished academic independence, “extreme centrism”, and conflicted/competing interests among innovation actors. Extreme centrism is of particular importance as a new ideology emerging from consortia science and consortia ethics; this relates to invariably taking a middle-of-the-road populist stance, even in the event of human rights breaches, so as to sustain the populist support needed for consortia building and collective innovation. What role do law, human rights, and bioethics—separate and together—have to play in addressing these predicaments and opportunities in early 21st century science and society? One answer we propose is an intertwined ethico-legal normative construct, namely trustworthiness. By considering trustworthiness as a central pillar at the intersection of law, human rights, and bioethics, we enable others to trust us, which in turns allows different actors (both nonprofit and for-profit to operate more justly in consortia science and ethics, as well as to access and responsibly use health data for public benefit.

  16. What Role for Law, Human Rights, and Bioethics in an Age of Big Data, Consortia Science, and Consortia Ethics? The Importance of Trustworthiness.

    Science.gov (United States)

    Dove, Edward S; Özdemir, Vural

    2015-09-01

    The global bioeconomy is generating new paradigm-shifting practices of knowledge co-production, such as collective innovation; large-scale, data-driven global consortia science (Big Science); and consortia ethics (Big Ethics). These bioeconomic and sociotechnical practices can be forces for progressive social change, but they can also raise predicaments at the interface of law, human rights, and bioethics. In this article, we examine one such double-edged practice: the growing, multivariate exploitation of Big Data in the health sector, particularly by the private sector. Commercial exploitation of health data for knowledge-based products is a key aspect of the bioeconomy and is also a topic of concern among publics around the world. It is exacerbated in the current age of globally interconnected consortia science and consortia ethics, which is characterized by accumulating epistemic proximity, diminished academic independence, "extreme centrism", and conflicted/competing interests among innovation actors. Extreme centrism is of particular importance as a new ideology emerging from consortia science and consortia ethics; this relates to invariably taking a middle-of-the-road populist stance, even in the event of human rights breaches, so as to sustain the populist support needed for consortia building and collective innovation. What role do law, human rights, and bioethics-separate and together-have to play in addressing these predicaments and opportunities in early 21st century science and society? One answer we propose is an intertwined ethico-legal normative construct, namely trustworthiness. By considering trustworthiness as a central pillar at the intersection of law, human rights, and bioethics, we enable others to trust us, which in turns allows different actors (both nonprofit and for-profit) to operate more justly in consortia science and ethics, as well as to access and responsibly use health data for public benefit.

  17. Making sense of information in noisy networks: human communication, gossip, and distortion.

    Science.gov (United States)

    Laidre, Mark E; Lamb, Alex; Shultz, Susanne; Olsen, Megan

    2013-01-21

    Information from others can be unreliable. Humans nevertheless act on such information, including gossip, to make various social calculations, thus raising the question of whether individuals can sort through social information to identify what is, in fact, true. Inspired by empirical literature on people's decision-making when considering gossip, we built an agent-based simulation model to examine how well simple decision rules could make sense of information as it propagated through a network. Our simulations revealed that a minimalistic decision-rule 'Bit-wise mode' - which compared information from multiple sources and then sought a consensus majority for each component bit within the message - was consistently the most successful at converging upon the truth. This decision rule attained high relative fitness even in maximally noisy networks, composed entirely of nodes that distorted the message. The rule was also superior to other decision rules regardless of its frequency in the population. Simulations carried out with variable agent memory constraints, different numbers of observers who initiated information propagation, and a variety of network types suggested that the single most important factor in making sense of information was the number of independent sources that agents could consult. Broadly, our model suggests that despite the distortion information is subject to in the real world, it is nevertheless possible to make sense of it based on simple Darwinian computations that integrate multiple sources.

  18. Considerations in applying compressed sensing to in vivo phosphorus MR spectroscopic imaging of human brain at 3T.

    Science.gov (United States)

    Hatay, Gokce Hale; Yildirim, Muhammed; Ozturk-Isik, Esin

    2017-08-01

    The purpose of this study was to apply compressed sensing method for accelerated phosphorus MR spectroscopic imaging ((31)P-MRSI) of human brain in vivo at 3T. Fast (31)P-MRSI data of five volunteers were acquired on a 3T clinical MR scanner using pulse-acquire sequence with a pseudorandom undersampling pattern for a data reduction factor of 5.33 and were reconstructed using compressed sensing. Additionally, simulated (31)P-MRSI human brain tumor datasets were created to analyze the effects of k-space sampling pattern, data matrix size, regularization parameters of the reconstruction, and noise on the compressed sensing accelerated (31)P-MRSI data. The (31)P metabolite peak ratios of the full and compressed sensing accelerated datasets of healthy volunteers in vivo were similar according to the results of a Bland-Altman test. The estimated effective spatial resolution increased with reduction factor and sampling more at the k-space center. A lower regularization parameter for both total variation and L1-norm penalties resulted in a better compressed sensing reconstruction of (31)P-MRSI. Although the root-mean-square error increased with noise levels, the compressed sensing reconstruction was robust for up to a reduction factor of 10 for the simulated data that had sharply defined tumor borders. As a result, compressed sensing was successfully applied to accelerate (31)P-MRSI of human brain in vivo at 3T.

  19. [Ethics and values in professional training in health: a case study].

    Science.gov (United States)

    Finkler, Mirelle; Caetano, João Carlos; Ramos, Flávia Regina Souza

    2013-10-01

    The scope of this research was to analyze the ethical dimension of the training of health professionals, specifically in Dentistry. Interviews were conducted with teachers, in addition to observation of academic activities and focus groups with students of two undergraduate courses. Data analysis revealed some elements of the hidden curriculum that influences the ethical dimension of training. The results discussed here suggest different ethical concepts in the academic environment with the predominance of an implicit code of ethics, the consequences of which require attention in the management of daily ethical conflicts. Based on common sense and a lack of intentionality of the academic staff with respect to the ethical training of students, it is imperative to know the values + they cherish in order to understand their moral development and identify a bioethical benchmark upon which the pedagogical-ethical issue is grounded. By way of conclusion, it is essential to assume individual and collective teaching responsibility for the ethical dimension of training in order that the professional training also has the potential for the integrated training of the human being as a whole.

  20. [Medical ethics as professional ethics].

    Science.gov (United States)

    Kwon, Ivo

    2012-09-25

    Contemporary medical ethics is far from the traditional concept of "In-Sul (benevolent art)" or "Yul-Li (倫, ethics), which emphasizes so much the personality or the character of a doctor. Nowadays, medical ethics should be considered as "professional ethics" which regulates the acts and medical practices of ordinary doctors in their daily practice. The key concepts of the professional ethics are "autonomy", "integrity", and "professional standard" established by medical organizations such as medical societies or associations. Most of Korean doctors have not been familiar with the concept of professional ethics or professionalism, which is due to the modern history of Korea. However, the concept of professional ethics is really critical to Korean doctors from the perspective of professional dignity and social respect to this profession. The current healthcare system of Korea is suffering from many problems of both private and public sector. Nonetheless, the professional ethics is urgently demanded for that very reason.

  1. Some Ethical-Moral Concerns in Administration.

    Science.gov (United States)

    Enns, Frederick

    1981-01-01

    Presents and analyzes moral-ethical issues that arise in administration and concludes that past descriptive, objective, and scientific approaches to administration have failed to take full account of the moral-ethical dimension of human existence. (Author/WD)

  2. Some Ethical-Moral Concerns in Administration.

    Science.gov (United States)

    Enns, Frederick

    1981-01-01

    Presents and analyzes moral-ethical issues that arise in administration and concludes that past descriptive, objective, and scientific approaches to administration have failed to take full account of the moral-ethical dimension of human existence. (Author/WD)

  3. The concept of human dignity in the ethics of genetic research.

    Science.gov (United States)

    Chan, David K

    2015-05-01

    Despite criticism that dignity is a vague and slippery concept, a number of international guidelines on bioethics have cautioned against research that is contrary to human dignity, with reference specifically to genetic technology. What is the connection between genetic research and human dignity? In this article, I investigate the concept of human dignity in its various historical forms, and examine its status as a moral concept. Unlike Kant's ideal concept of human dignity, the empirical or relational concept takes human dignity as something that is affected by one's circumstances and what others do. I argue that the dignity objection to some forms of genetic research rests on a view of human nature that gives humans a special status in nature - one that is threatened by the potential of genetic research to reduce individuals to their genetic endowment. I distinguish two main philosophical accounts of human nature. One of these, the Aristotelian view, is compatible with the use of genetic technology to help humans realize their inherent potential to a fuller extent.

  4. Detecting land use changes affected by human activities using remote sensing (Case study: Karkheh River Basin

    Directory of Open Access Journals (Sweden)

    Saeid Maddah

    2015-08-01

    Full Text Available Population growth and abundant activities in order to achieve maximum well-being has forced human to make a lot of changes in the nature. These changes will be cost-effective when they have the minimum damage on the landscape. One of the activities that human did for obtaining the water and preventing flood was making the dam in the track of running water. Since the dam is established until its impoundment and after impoundment, the condition of ecosystem and the appearance of the upstream and downstream of the dam will undergo changes. In this study, using satellite data and remote sensing, these changes have been studied and the landuse changes in vegetation, arid land, water level and residential and non-residential lands is measured in 1998 and 2014 using Maximum Likelihood method and support vector machine.

  5. Estimating three-dimensional orientation of human body parts by inertial/magnetic sensing.

    Science.gov (United States)

    Sabatini, Angelo Maria

    2011-01-01

    User-worn sensing units composed of inertial and magnetic sensors are becoming increasingly popular in various domains, including biomedical engineering, robotics, virtual reality, where they can also be applied for real-time tracking of the orientation of human body parts in the three-dimensional (3D) space. Although they are a promising choice as wearable sensors under many respects, the inertial and magnetic sensors currently in use offer measuring performance that are critical in order to achieve and maintain accurate 3D-orientation estimates, anytime and anywhere. This paper reviews the main sensor fusion and filtering techniques proposed for accurate inertial/magnetic orientation tracking of human body parts; it also gives useful recipes for their actual implementation.

  6. The ethics of cultural competence.

    Science.gov (United States)

    Paasche-Orlow, Michael

    2004-04-01

    Cultural competence curricula have proliferated throughout medical education. Awareness of the moral underpinnings of this movement can clarify the purpose of such curricula for educators and trainees and serve as a way to evaluate the relationship between the ethics of cultural competence and normative Western medical ethics. Though rarely stated explicitly, the essential principles of cultural competence are (1) acknowledgement of the importance of culture in people's lives, (2) respect for cultural differences, and (3) minimization of any negative consequences of cultural differences. Culturally competent clinicians promote these principles by learning about culture, embracing pluralism, and proactive accommodation. Generally, culturally competent care will advance patient autonomy and justice. In this sense, cultural competence and Western medical ethics are mutually supportive movements. However, Western bioethics and the personal ethical commitments of many medical trainees will place limits on the extent to which they will endorse pluralism and accommodation. Specifically, if the values of cultural competence are thought to embrace ethical relativity, inexorable conflicts will be created. The author presents his view of the ethics of cultural competence and places the concepts of cultural competence in the context of Western moral theory. Clarity about the ethics of cultural competence can help educators promote and evaluate trainees' integration of their own moral intuitions, Western medical ethics, and the ethics of cultural competence.

  7. Remote sensing captures varying temporal patterns of vegetation between human-altered and natural landscapes.

    Science.gov (United States)

    Leong, Misha; Roderick, George K

    2015-01-01

    Global change has led to shifts in phenology, potentially disrupting species interactions such as plant-pollinator relationships. Advances in remote sensing techniques allow one to detect vegetation phenological diversity between different land use types, but it is not clear how this translates to other communities in the ecosystem. Here, we investigated the phenological diversity of the vegetation across a human-altered landscape including urban, agricultural, and natural land use types. We found that the patterns of change in the vegetation indices (EVI and NDVI) of human-altered landscapes are out of synchronization with the phenology in neighboring natural California grassland habitat. Comparing these findings to a spatio-temporal pollinator distribution dataset, EVI and NDVI were significant predictors of total bee abundance, a relationship that improved with time lags. This evidence supports the importance of differences in temporal dynamics between land use types. These findings also highlight the potential to utilize remote sensing data to make predictions for components of biodiversity that have tight vegetation associations, such as pollinators.

  8. Remote sensing captures varying temporal patterns of vegetation between human-altered and natural landscapes

    Directory of Open Access Journals (Sweden)

    Misha Leong

    2015-08-01

    Full Text Available Global change has led to shifts in phenology, potentially disrupting species interactions such as plant–pollinator relationships. Advances in remote sensing techniques allow one to detect vegetation phenological diversity between different land use types, but it is not clear how this translates to other communities in the ecosystem. Here, we investigated the phenological diversity of the vegetation across a human-altered landscape including urban, agricultural, and natural land use types. We found that the patterns of change in the vegetation indices (EVI and NDVI of human-altered landscapes are out of synchronization with the phenology in neighboring natural California grassland habitat. Comparing these findings to a spatio-temporal pollinator distribution dataset, EVI and NDVI were significant predictors of total bee abundance, a relationship that improved with time lags. This evidence supports the importance of differences in temporal dynamics between land use types. These findings also highlight the potential to utilize remote sensing data to make predictions for components of biodiversity that have tight vegetation associations, such as pollinators.

  9. A Method for Remotely Sensing Vital Signs of Human Subjects Outdoors

    Directory of Open Access Journals (Sweden)

    Chuantao Li

    2015-06-01

    Full Text Available After chemical or nuclear leakage or explosions, finding survivors is a huge challenge. Although human bodies can be found by smart vehicles and drones equipped with cameras, it is difficult to verify if the person is alive or dead this way. This paper describes a continuous wave radar sensor for remotely sensing the vital signs of human subjects. Firstly, a compact and portable 24 GHz Doppler radar system is designed to conduct non-contact detection of respiration signal. Secondly, in order to improve the quality of the respiration signals, the self-correlation and adaptive line enhancer (ALE methods are proposed to minimize the interferences of any moving objects around the human subject. Finally, the detection capabilities of the radar system and the signal processing method are verified through experiments which show that human respiration signals can be extracted when the subject is 7 m away outdoors. The method provided in this paper will be a promising way to search for human subjects outdoors.

  10. Mimicking the human smell sensing mechanism with an artificial nose platform.

    Science.gov (United States)

    Lee, Sang Hun; Kwon, Oh Seok; Song, Hyun Seok; Park, Seon Joo; Sung, Jong Hwan; Jang, Jyongsik; Park, Tai Hyun

    2012-02-01

    Sensing smell is a highly complex biological process, and characterizing and mimicking the interaction between the olfactory receptor (OR) protein and its ligands is extremely challenging. Herein, we report a highly sensitive and selective human nose-like nanobioelectronic nose (nbe-nose), which responds to gaseous odorants sensitively and selectively, has a signal specificity pattern similar to that in the cellular signal transduction pathway, and maintains an antagonistic behavior similar to the human nose. The human olfaction mechanism was mimicked by using carboxylated polypyrrole nanotubes (CPNTs) functionalized with human OR protein. The nbe-nose was able to detect gaseous odorants at a concentration as low as 0.02 parts-per-trillion (ppt), which was comparable to a highly trained, human expert's nose. The nbe-nose can be used scientifically for smell mechanism studies. It can be also applied to various fields that rely on smell monitoring for industrial and public purposes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. A Method for Remotely Sensing Vital Signs of Human Subjects Outdoors

    Science.gov (United States)

    Li, Chuantao; Chen, Fuming; Jin, Jingxi; Lv, Hao; Li, Sheng; Lu, Guohua; Wang, Jianqi

    2015-01-01

    After chemical or nuclear leakage or explosions, finding survivors is a huge challenge. Although human bodies can be found by smart vehicles and drones equipped with cameras, it is difficult to verify if the person is alive or dead this way. This paper describes a continuous wave radar sensor for remotely sensing the vital signs of human subjects. Firstly, a compact and portable 24 GHz Doppler radar system is designed to conduct non-contact detection of respiration signal. Secondly, in order to improve the quality of the respiration signals, the self-correlation and adaptive line enhancer (ALE) methods are proposed to minimize the interferences of any moving objects around the human subject. Finally, the detection capabilities of the radar system and the signal processing method are verified through experiments which show that human respiration signals can be extracted when the subject is 7 m away outdoors. The method provided in this paper will be a promising way to search for human subjects outdoors. PMID:26115454

  12. Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue.

    Directory of Open Access Journals (Sweden)

    Diana Fatykhova

    Full Text Available Streptococcus pneumoniae is a major cause of pneumonia, sepsis and meningitis. The pore-forming toxin pneumolysin is a key virulence factor of S. pneumoniae, which can be sensed by the NLRP3 inflammasome. Among the over 90 serotypes, serotype 1 pneumococci (particularly MLST306 have emerged across the globe as a major cause of invasive disease. The cause for its particularity is, however, incompletely understood. We therefore examined pneumococcal infection in human cells and a human lung organ culture system mimicking infection of the lower respiratory tract. We demonstrate that different pneumococcal serotypes differentially activate inflammasome-dependent IL-1β production in human lung tissue and cells. Whereas serotype 2, 3, 6B, 9N pneumococci expressing fully haemolytic pneumolysins activate NLRP3 inflammasome-dependent responses, serotype 1 and 8 strains expressing non-haemolytic toxins are poor activators of IL-1β production. Accordingly, purified haemolytic pneumolysin but not serotype 1-associated non-haemolytic toxin activates strong IL-1β production in human lungs. Our data suggest that the evasion of inflammasome-dependent innate immune responses by serotype 1 pneumococci might contribute to their ability to cause invasive diseases in humans.

  13. Toward Cosmopolitan Ethics in Teacher Education: An Ontological Dimension of Learning Human Rights

    Science.gov (United States)

    Adami, Rebecca

    2014-01-01

    There is a globalization trend in teacher education, emphasizing the role of teachers to make judgments based on human rights in their teaching profession. Rather than emphasizing the epistemological dimension of acquiring knowledge "about" human rights through teacher education, an ontological dimension is emphasized in this paper of…

  14. Toward Cosmopolitan Ethics in Teacher Education: An Ontological Dimension of Learning Human Rights

    Science.gov (United States)

    Adami, Rebecca

    2014-01-01

    There is a globalization trend in teacher education, emphasizing the role of teachers to make judgments based on human rights in their teaching profession. Rather than emphasizing the epistemological dimension of acquiring knowledge "about" human rights through teacher education, an ontological dimension is emphasized in this paper of…

  15. Computer science security research and human subjects: emerging considerations for research ethics boards.

    Science.gov (United States)

    Buchanan, Elizabeth; Aycock, John; Dexter, Scott; Dittrich, David; Hvizdak, Erin

    2011-06-01

    This paper explores the growing concerns with computer science research, and in particular, computer security research and its relationship with the committees that review human subjects research. It offers cases that review boards are likely to confront, and provides a context for appropriate consideration of such research, as issues of bots, clouds, and worms enter the discourse of human subjects review.

  16. Addressing the ethical issues raised by synthetic human entities with embryo-like features

    NARCIS (Netherlands)

    Aach, John; Lunshof, Jeantine; Iyer, Eswar; Church, George M.

    2017-01-01

    The "14-day rule" for embryo research stipulates that experiments with intact human embryos must not allow them to develop beyond 14 days or the appearance of the primitive streak. However, recent experiments showing that suitably cultured human pluripotent stem cells can self organize and recapitul

  17. Perspective Intercultural Bioethics and Human Rights: the search for instruments for resolving ethical conflicts culturally based.

    Directory of Open Access Journals (Sweden)

    Aline ALBUQUERQUE

    2015-10-01

    Full Text Available This article aims to contribute to a deeper reflection on intercultural conflicts within the bioethics scope, and to point out the problem of using human rights as a theoretical normative mediator of the conflicts in bioethics that bear elements of interculturalism. The methodological steps adopted in this inquiry were: analysis of the concept of intercultural conflict in bioethics, from the perception developed by Colectivo Amani; study of human rights as tools of the culture of human beings, based on Bauman’s and Beauchamp’s theories; investigation of the toolsthat human rights offer so as to solve intercultural conflicts in bioethics. It was concluded that intercultural bioethics must incorporate to its prescriptive and descriptive tasks norms and institutions of human rights that ensure the participation and social integration of the individuals from communities that are in cultural conflict. Such measure will act as instrumentsfor the solution of intercultural conflicts.

  18. Human love--the inner essence of nursing ethics according to Estrid Rodhe. A study using the approach of history of ideas.

    Science.gov (United States)

    Kangasniemi, Mari; Haho, Annu

    2012-12-01

    The aim of this study is to describe the idea pattern of nursing ethics in the textbook written by the Swedish nurse Estrid Rodhe (1911). The purpose is to increase understanding of the ideas in early written history of nursing ethics by using the method of history of ideas. A theoretical premise, but also a fascinating factor in this study, is that the ethics of one profession is always contextual in relation to current period. The historical context of Rodhe's time was a time of difficult societal circumstances in Europe. Nurses' work was demanding, but a distinctive feature was enthusiasm to develop nursing. Discussion of the moral issues of nursing was intense, and the characteristics of a good nurse consisted of being as altruistic and unselfish woman. Based on our analysis, the inner essence of Rodhe's idea pattern consists of human love. It is reflected in her ideas of calling-based altruism, virtuous woman as a personal reason for being a nurse and nurses' ethical duty to implementation and subservience. Rodhe's thinking reflects the conventions of her time. The role of personal moral characteristics of nurses was highlighted and not viewed as separable from the professional. Her textbook represented nursing knowledge of ethics written by a nurse and making her a pioneer of the early written history of nursing in general. Understanding the past helps us comprehend current issues in nursing and makes visible cultural values that form the basis for today and tomorrow. It also provides a possibility to observe the same fundamental features in spite of temporal distance. Here, the history of ideas is a beneficial and fruitful method to increase our understanding of nursing ethics.

  19. Universalism, particularism and the ethics of dignity.

    Science.gov (United States)

    Pullman, Daryl

    2001-12-01

    This paper explores the problem of universalism and particularism in contemporary ethics, and its relationship to Christian bioethics in particular. An ethic of human dignity is outlined, which, it is argued, constrains moral discourse in the broad sense--thus meeting the demands of universalism--but which is at the same time amenable to a variety of particularist interpretations--thus acknowledging the current shift toward historicism, traditionalism, and culture. The particularist interpretations that are of central concern here are those provided by historic Christianity. The eventual goal is to indicate how a Christian conception of human dignity can have universal normative relevance both as a standard against which to assess competing particularist conceptions, and as a practical guide for everyday living. A Christian conception of dignity will in turn have significant implications when addressing contemporary issues in bioethics. These are ambitious goals, and a full explication of the ideas presented will not be possible in this context. Nevertheless, there is value in getting a bird's-eye view of the landscape before one goes about scaling the mountains and exploring the valleys. The present essay is intended as a general geography of the moral terrain in which an ethic of dignity in general, and a Christian perspective on dignity in particular, can provide normative guidance.

  20. Ethics in actor networks, or: what Latour could learn from Darwin and Dewey.

    Science.gov (United States)

    Waelbers, Katinka; Dorstewitz, Philipp

    2014-03-01

    In contemporary Science, Technology and Society (STS) studies, Bruno Latour's Actor Network Theory (ANT) is often used to study how social change arises from interaction between people and technologies. Though Latour's approach is rich in the sense of enabling scholars to appreciate the complexity of many relevant technological, environmental, and social factors in their studies, the approach is poor from an ethical point of view: the doings of things and people are couched in one and the same behaviorist (third person) vocabulary without giving due recognition to the ethical relevance of human intelligence, sympathy and reflection in making responsible choices. This article argues that two other naturalist projects, the non-teleological virtue ethics of Charles Darwin and the pragmatist instrumentalism of John Dewey can enrich ANT-based STS studies, both, in a descriptive and in a normative sense.

  1. Business ethics in ethics committees?

    Science.gov (United States)

    Boyle, P

    1990-01-01

    The "Ethics committees" column in this issue of the Hastings Center Report features an introduction by Cynthia B. Cohen and four brief commentaries on the roles hospital ethics committees may play in the making of institutional and public health care policy in the 1990s. The pros and cons of a broader, more public role for ethics committees in reconciling the business and patient care aspects of health care delivery are debated by Cohen in "Ethics committees as corporate and public policy advocates," and by Philip Boyle in this article. Boyle is an associate for ethical studies at The Hastings Center.

  2. Ethical attitudes on human cloning among professionals in Taiwan and the policy implications for regulation.

    Science.gov (United States)

    Yang, Che-Ming; Chung, Chun-Chih; Lu, Meei-Shiow; Lin, Chiou-Fen; Chen, Jiun-Shyan

    2005-01-01

    This research focused on understanding the attitudes toward human cloning in Taiwan among professionals in healthcare, law, and religion. The study was conducted utilizing a structured questionnaire. 220 healthcare professionals from two regional hospitals located in Taipei, 351 religious professionals in the northern Taiwan and 711 legal professionals were selected by to receive questionnaires. The valid response rate is 42.1% The questions were generated by an expert panel and represented major arguments in the human cloning debate. There were a total of six Likert scaled questions in the questionnaire. The responses were coded from 1 to 5 with 1 representing strong opposition to human cloning, 3 representing a neutral attitude; and 5 representing a strong favorable attitude toward human cloning. Healthcare professionals had the highest overall average score of 2.14 and the religious professionals had the lowest average at 1.58. All three categories of respondents' attitude toward cloning ranged from mild opposition to strong opposition to human cloning. The religious professionals were more strongly opposed to cloning. Age, education, and religion significantly influenced attitudes toward cloning. Professionals between fifty-one and sixty years old, those with less education, and Roman Catholic professionals were more strongly opposed to cloning. Religious professionals were more strongly opposed to human cloning than professionals in healthcare or law. Younger professionals as an age group demonstrated less opposition to human cloning. Regulation of human cloning will be influenced by professionals in healthcare, law, and religion, and the regulatory environment chosen now will play a pivotal role in influencing the acceptance of human cloning in the future.

  3. cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

    Science.gov (United States)

    Paijo, Jennifer; Döring, Marius; Spanier, Julia; Grabski, Elena; Nooruzzaman, Mohammed; Schmidt, Tobias; Witte, Gregor; Messerle, Martin; Hornung, Veit; Kaever, Volkhard; Kalinke, Ulrich

    2016-01-01

    Human cytomegalovirus (HCMV) infections of healthy individuals are mostly unnoticed and result in viral latency. However, HCMV can also cause devastating disease, e.g., upon reactivation in immunocompromised patients. Yet, little is known about human immune cell sensing of DNA-encoded HCMV. Recent studies indicated that during viral infection the cyclic GMP/AMP synthase (cGAS) senses cytosolic DNA and catalyzes formation of the cyclic di-nucleotide cGAMP, which triggers stimulator of interferon genes (STING) and thus induces antiviral type I interferon (IFN-I) responses. We found that plasmacytoid dendritic cells (pDC) as well as monocyte-derived DC and macrophages constitutively expressed cGAS and STING. HCMV infection further induced cGAS, whereas STING expression was only moderately affected. Although pDC expressed particularly high levels of cGAS, and the cGAS/STING axis was functional down-stream of STING, as indicated by IFN-I induction upon synthetic cGAMP treatment, pDC were not susceptible to HCMV infection and mounted IFN-I responses in a TLR9-dependent manner. Conversely, HCMV infected monocyte-derived cells synthesized abundant cGAMP levels that preceded IFN-I production and that correlated with the extent of infection. CRISPR/Cas9- or siRNA-mediated cGAS ablation in monocytic THP-1 cells and primary monocyte-derived cells, respectively, impeded induction of IFN-I responses following HCMV infection. Thus, cGAS is a key sensor of HCMV for IFN-I induction in primary human monocyte-derived DC and macrophages. PMID:27058035

  4. Biotechnology, Ethics and Education

    Science.gov (United States)

    Fitzsimons, Peter John

    2007-01-01

    Fundamental differences between current and past knowledge in the field of biotechnology mean that we now have at our disposal the means to irreversibly change what is meant by "human nature". This paper explores some of the ethical issues that accompany the (as yet tentative) attempt to increase scientific control over the human genetic code in…

  5. Furthering the sceptical case against virtue ethics in nursing ethics.

    Science.gov (United States)

    Holland, Stephen

    2012-10-01

    In a recent article in this journal I presented a sceptical argument about the current prominence of virtue ethics in nursing ethics. Daniel Putman has responded with a defence of the relevance of virtue in nursing. The present article continues this discussion by clarifying, defending, and expanding the sceptical argument. I start by emphasizing some features of the sceptical case, including assumptions about the nature of sceptical arguments, and about the character of both virtue ethics and nursing ethics. Then I respond to objections of Putman's such as that, according to virtue ethics, virtue is relevant to the whole of a human life, including one's behaviour in a professional context; and that eudaimonia should be central in explaining and motivating a nurse's decision to enter the profession. Having argued that these objections are not compelling, I go on to discuss an interesting recent attempt to reassert the role of virtue ethics in the ethics of professions, including nursing. This centres on whether role-specific obligations - e.g. the obligations that arise for a moral agent qua lawyer or mother - can be accommodated in a virtue ethics approach. Sean Cordell has argued that the difficulty of accommodating role-specific obligations results in an 'institution-shaped gap' in virtue ethics. He suggests a way of meeting this difficulty that appeals to the ergon of institutions. I endorse the negative point that role-specific obligations elude virtue ethics, but argue that the appeal to the ergon of institutions is unsuccessful. The upshot is further support for scepticism about the virtue ethics approach to nursing ethics. I end by gesturing to some of the advantages of a sceptical view of virtue ethics in nursing ethics. © 2012 Blackwell Publishing Ltd.

  6. Reflexiones sobre los principios éticos en investigación biomedica en seres humanos Ethical principles in biomedical research involving human beings

    Directory of Open Access Journals (Sweden)

    MARIANNE GAUDLITZ H

    2008-01-01

    Full Text Available La investigación biomedica en seres humanos plantea problemas valóneos. Una investigación científica debe ir de la mano de una serie de requisitos para que sea una investigación ética. La trayectoria de la investigación en el mundo occidental no ha estado libre de abusos. Las normas éticas internacionales han aparecido después de las transgresiones. La protección de los probandos que participan libre y voluntariamente en una investigación biomedica es una obligación ética, la dignidad de éstos está por sobre el progreso de la ciencia y el bienestar que éste acarrearíaBiomedical research involving human subjects present valoric problems. A scientific research must go hand in hand with several requisites to be ethic. Human experimentation through its history in the occidental world has not been exempt from abuses. Ethic international rules have appeared after the transgressions. The protection of the human beings that freely and willingly participate in a biomedical research is an ethic obligation. The dignity of the human beings is above the progress of science and the wealth it carries with it

  7. Justice and medical ethics.

    Science.gov (United States)

    Gillon, R

    1985-07-20

    Justice, in the sense of fair adjudication between conflicting claims, is held to be relevant to a wide range of issues in medical ethics. Several differing concepts of justice are briefly described, including Aristotle's formal principle of justice, libertarian theories, utilitarian theories, Marxist theories, the theory of John Rawls, and the view--held, for example, by W.D. Ross--that justice is essentially a matter of reward for individual merit.

  8. Just Another Reproductive Technology? The Ethics of Human Reproductive Cloning as an Experimental Medical Procedure

    National Research Council Canada - National Science Library

    D. Elsner

    2006-01-01

    Human reproductive cloning (HRC) has not yet resulted in any live births. There has been widespread condemnation of the practice in both the scientific world and the public sphere, and many countries explicitly outlaw the practice...

  9. The ethics of characterizing difference: guiding principles on using racial categories in human genetics.

    Science.gov (United States)

    Lee, Sandra Soo-Jin; Mountain, Joanna; Koenig, Barbara; Altman, Russ; Brown, Melissa; Camarillo, Albert; Cavalli-Sforza, Luca; Cho, Mildred; Eberhardt, Jennifer; Feldman, Marcus; Ford, Richard; Greely, Henry; King, Roy; Markus, Hazel; Satz, Debra; Snipp, Matthew; Steele, Claude; Underhill, Peter

    2008-01-01

    We are a multidisciplinary group of Stanford faculty who propose ten principles to guide the use of racial and ethnic categories when characterizing group differences in research into human genetic variation.

  10. Clinical ethics and nursing: "yes" to caring, but "no" to a female ethics of care.

    Science.gov (United States)

    Kuhse, Helga

    1995-07-01

    According to a contemporary school of thought there is a specific female approach to ethics which is based not on abstract "male" ethical principles or rules, but on "care". Nurses have taken a keen interest in these female approaches to ethics. Drawing on the views expounded by Carol Gilligan and Nel Noddings, nurses claim that a female "ethics of care" better captures their moral experiences than a traditional male "ethics of justice". This paper argues that "care" is best understood in a dispositional sense, that is, as sensitivity and responsiveness to the particularities of a situation and the needs of "concrete" others. While "care", in this sense, is necessary for ethics, it is not sufficient. Ethics needs "justice" as well as "care". If women and nurses excessively devalue principles and norms, they will be left without the theoretical tools to condemn some actions or practices, and to defend others. They will, like generations of nurses before them, be condemned to silence.

  11. Ubiquitous Geo-Sensing for Context-Aware Analysis: Exploring Relationships between Environmental and Human Dynamics

    Directory of Open Access Journals (Sweden)

    Euro Beinat

    2012-07-01

    Full Text Available Ubiquitous geo-sensing enables context-aware analyses of physical and social phenomena, i.e., analyzing one phenomenon in the context of another. Although such context-aware analysis can potentially enable a more holistic understanding of spatio-temporal processes, it is rarely documented in the scientific literature yet. In this paper we analyzed the collective human behavior in the context of the weather. We therefore explored the complex relationships between these two spatio-temporal phenomena to provide novel insights into the dynamics of urban systems. Aggregated mobile phone data, which served as a proxy for collective human behavior, was linked with the weather data from climate stations in the case study area, the city of Udine, Northern Italy. To identify and characterize potential patterns within the weather-human relationships, we developed a hybrid approach which integrates several spatio-temporal statistical analysis methods. Thereby we show that explanatory factor analysis, when applied to a number of meteorological variables, can be used to differentiate between normal and adverse weather conditions. Further, we measured the strength of the relationship between the ‘global’ adverse weather conditions and the spatially explicit effective variations in user-generated mobile network traffic for three distinct periods using the Maximal Information Coefficient (MIC. The analyses result in three spatially referenced maps of MICs which reveal interesting insights into collective human dynamics in the context of weather, but also initiate several new scientific challenges.

  12. Design of a Handheld Pseudo Random Coded UWB Radar for Human Sensing

    Directory of Open Access Journals (Sweden)

    Xia Zheng-huan

    2015-10-01

    Full Text Available This paper presents the design of a handheld pseudo random coded Ultra-WideBand (UWB radar for human sensing. The main tasks of the radar are to track the moving human object and extract the human respiratory frequency. In order to achieve perfect penetrability and good range resolution, m sequence with a carrier of 800 MHz is chosen as the transmitting signal. The modulated m-sequence can be generated directly by the high-speed DAC and FPGA to reduce the size of the radar system, and the mean power of the transmitting signal is 5 dBm. The receiver has two receiving channels based on hybrid sampling, the first receiving channel is to sample the reference signal and the second receiving channel is to obtain the radar echo. The real-time pulse compression is computed in parallel with a group of on-chip DSP48E slices in FPGA to improve the scanning rate of the radar system. Additionally, the algorithms of moving target tracking and life detection are implemented using Intel’s micro-processor, and the detection results are sent to the micro displayer fixed on the helmet. The experimental results show that the moving target located at less than 16 m far away from the wall can be tracked, and the respiratory frequency of the static human at less than 14 m far away from the wall can be extracted.

  13. An Impact of Social Code of Conduct as a Determinant of Ethical Conduct on Human Resources Practices from the Aspect of Strategic Management

    Directory of Open Access Journals (Sweden)

    Harun Demirkaya

    2013-09-01

    Full Text Available This study analyzes the social code of conduct as a determinant of ethical conduct on human resources practices in terms of strategic management and investigates how effective the factor of social conduct is in the human resources managers’ decisions and actions. As a result, it has been seen that human resources managers have a positive attitude towards the employees having advanced social conduct and confirmed that the employees having advanced social conduct have an advantage over their peers in many organizational practices beginning from the recruitment process.

  14. Christian ethic of love and Hindu ethic of dharma: comparative analysis

    Directory of Open Access Journals (Sweden)

    Pavenkov Oleg Vladimirovich

    2014-10-01

    Full Text Available This article is devoted to comparative analysis of two ethic systems: Hindu ethic of dharma and Christian ethic of love. If Christian ethic is the ethic of love, love is in the center of Christian moral values, then Hindu ethic is an example of ethic of law. The moral behavior of gods and humans is determined by Karma and cycle of samsara, which is impossible in Christianity. However forgiveness, self-restraint, non-stealing, purity are common moral obligations for Christians and Hindus.

  15. Position sense at the human elbow joint measured by arm matching or pointing.

    Science.gov (United States)

    Tsay, Anthony; Allen, Trevor J; Proske, Uwe

    2016-10-01

    Position sense at the human elbow joint has traditionally been measured in blindfolded subjects using a forearm matching task. Here we compare position errors in a matching task with errors generated when the subject uses a pointer to indicate the position of a hidden arm. Evidence from muscle vibration during forearm matching supports a role for muscle spindles in position sense. We have recently shown using vibration, as well as muscle conditioning, which takes advantage of muscle's thixotropic property, that position errors generated in a forearm pointing task were not consistent with a role by muscle spindles. In the present study we have used a form of muscle conditioning, where elbow muscles are co-contracted at the test angle, to further explore differences in position sense measured by matching and pointing. For fourteen subjects, in a matching task where the reference arm had elbow flexor and extensor muscles contracted at the test angle and the indicator arm had its flexors conditioned at 90°, matching errors lay in the direction of flexion by 6.2°. After the same conditioning of the reference arm and extension conditioning of the indicator at 0°, matching errors lay in the direction of extension (5.7°). These errors were consistent with predictions based on a role by muscle spindles in determining forearm matching outcomes. In the pointing task subjects moved a pointer to align it with the perceived position of the hidden arm. After conditioning of the reference arm as before, pointing errors all lay in a more extended direction than the actual position of the arm by 2.9°-7.3°, a distribution not consistent with a role by muscle spindles. We propose that in pointing muscle spindles do not play the major role in signalling limb position that they do in matching, but that other sources of sensory input should be given consideration, including afferents from skin and joint.

  16. Research about Medical Experiments Investigation Ethics on Human beings in China%我国医学人体试验伦理审查问题研究

    Institute of Scientific and Technical Information of China (English)

    张建莹; 何强

    2016-01-01

    With the rapid development of Chinese medicine these years, a growing number of research projects involving human subjects. Human trial is an irreplaceable means and the double impacts it brings also attracted attention of the whole society. Ethical review of human subjects in medical research for the development of the whole has a vital role. At present, China has been on a preliminary human trials of medical ethics review of the concept, but understanding of the nature and functions of the ethics review is not enough, and regulatory aspects of the formation of the ethics committee is also prob-lematic. Our country does not have a special law to regulate human trials of medical ethics review, and the relevant laws and regulations are not perfect. Here’s some main problems we still need to work on, how to improve our medical experi-ments investigation on human beings, human subjects under protected, guaranteeing medical experiments way to right.%随着我国近年来医学事业的迅猛发展,人体试验的科研项目越来越多。人体试验是我国医学科研发展中不可替代的必要手段之一,它带给人类的双重影响也引起了全社会的高度重视。对我国医学人体试验进行伦理审查至关重要,它不仅保护受试者的合法权益,对我国医学科研的健康发展也起到了积极作用。尽管我国对医学人体试验伦理审查已有了初步的概念,但是对伦理审查的职能、性质不够规范;伦理委员会组建和监管方面存在问题;医学人体试验伦理审查的相关法律并不完善等。如何改善我国医学人体试验伦理审查,保护受试者合法权益不受侵犯,保障医学科研健康发展都是本文将要探讨研究的主要问题。

  17. 人类胚胎干细胞研究的伦理分析%Ethical Analysis of Human Embryonic Stem Cell Research

    Institute of Scientific and Technical Information of China (English)

    滕菲

    2015-01-01

    随着人类胚胎干细胞研究的深入,一些顽症的治愈成为可能的同时,避免了器官移植所带来的免疫排斥这一难题,但也引发了一系列与生命有关的伦理问题,这是当代生命伦理面临的一个巨大难题。现就从如何看待人类胚胎入手,分析人类胚胎干细胞研究带来伦理问题的原因,阐明了为人类胚胎干细胞的研究制定严格的伦理规范、伦理程序及完备的法制化保障的必要性。%With the in-depth research of human embryonic stem cells, a variety of chronic and stubborn diseases can be cured,and at the same time,it can avoid severe organ transplantation immune rejection. But the research caused a series of ethical issues related to the life, and is a big problem of the contemporary bioethics. This article will start from how to view human embryos, analyzes the cause of the ethical problems brought by human embryonic stem cell research, clarify the necessity of establishing strict ethical norms, ethical procedures and a perfect legal safeguard system for human embryonic stem cell research.

  18. Students as resurrectionists--A multimodal humanities project in anatomy putting ethics and professionalism in historical context.

    Science.gov (United States)

    Hammer, Rachel R; Jones, Trahern W; Hussain, Fareeda Taher Nazer; Bringe, Kariline; Harvey, Ronee E; Person-Rennell, Nicole H; Newman, James S

    2010-01-01

    Because medical students have many different learning styles, the authors, medical students at Mayo Clinic, College of Medicine researched the history of anatomical specimen procurement, reviewing topic-related film, academic literature, and novels, to write, direct, and perform a dramatization based on Robert Louis Stevenson's The Body-Snatcher. Into this performance, they incorporated dance, painting, instrumental and vocal performance, and creative writing. In preparation for the performance, each actor researched an aspect of the history of anatomy. These micro-research projects were presented in a lecture before the play. Not intended to be a research study, this descriptive article discusses how student research and ethics discussions became a theatrical production. This addition to classroom and laboratory learning addresses the deep emotional response experienced by some students and provides an avenue to understand and express these feelings. This enhanced multimodal approach to"holistic learning" could be applied to any topic in the medical school curriculum, thoroughly adding to the didactics with history, humanities, and team dynamics.

  19. Development of knowledge based operation system for making product matching with requirement by human sense; Kansei tekigo seihinseizo wo mezashita chiteki opereshon shisumtemu ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Honda, Hiroyuki [Nagoya University, Aichi (Japan). Dept. of Biotechnology

    1999-12-16

    Knowledge based operation system was developed in order to apply the human sense to process operation. Since beverages such as coffee, beer and sake, are seriously evaluated by human sense, those sensory evaluations or data on those chemical composition were subjected to this research. Fuzzy neural network (FNN) ro its hierarchical structure (HFNN) was superior tool for modeling of human sense. With respect to the determination of the chemical composition from desired sensory evaluation, an innovative tool, CF-GA, was newly developed. Using these tools, construction of knowledge based operation system for making the product matching with requirement by human sense became promising. (author)

  20. The Ethical Problems and Perspective of Human Genome%人类基因组伦理:问题与前景

    Institute of Scientific and Technical Information of China (English)

    沈铭贤

    2001-01-01

    人类基因组计划(HGP)试图在分子层次上更深入、更全面地认识人体,为战胜疾病增进健康提供科学依据,从而造福人类。这是人类认识生命、认识自身的自然而又必然的结果。必须反对“基因决定论”,保护基因隐私,防止基因歧视,警惕“优生运动”死灰复燃。HGP与生老病死密切相关,对伦理特别敏感,尤其要强调伦理的规范和引导作用,而不能把科技与伦理对立起来。%The aim of HGP is to know human body competely and to provide the scientific basis for curing illness and strengthening health.It is the result of realization of life and human themselves.We must object the theory of gene-decision,protect gene privacy,prevent gene discrimiation and “eugenics movement” recur.HGP is related to human from the cradle to the grave,which is sensitive to ethical problems,especially emphasis on the guidance of ethics;whereas to prevent antagonism between scientific technology and ethic.

  1. Human resource management in the project-oriented organization: Employee well-being and ethical treatment

    NARCIS (Netherlands)

    Turner, R.; Huemann, M.; Keegan, A.

    2008-01-01

    As part of a wider study into human resource management (HRM) practices in project-oriented organizations, we investigated the issue of employee well-being. Project-oriented organizations adopt temporary work processes to deliver products and services to clients. This creates a dynamic work environm

  2. Human resource management in the project-oriented organization: Employee well-being and ethical treatment

    NARCIS (Netherlands)

    Turner, R.; Huemann, M.; Keegan, A.

    2008-01-01

    As part of a wider study into human resource management (HRM) practices in project-oriented organizations, we investigated the issue of employee well-being. Project-oriented organizations adopt temporary work processes to deliver products and services to clients. This creates a dynamic work

  3. Universities and a Human Development Ethics: A Capabilities Approach to Curriculum

    Science.gov (United States)

    Walker, Melanie

    2012-01-01

    This article takes up the challenge of curriculum change in relation to the contested purposes of universities. It argues for an expansive, public good understanding, rather than the thin market exchange norms which currently drive higher education policies. The paper suggests that a human capital approach to curriculum is then insufficient to…

  4. Universities and a Human Development Ethics: A Capabilities Approach to Curriculum

    Science.gov (United States)

    Walker, Melanie

    2012-01-01

    This article takes up the challenge of curriculum change in relation to the contested purposes of universities. It argues for an expansive, public good understanding, rather than the thin market exchange norms which currently drive higher education policies. The paper suggests that a human capital approach to curriculum is then insufficient to…

  5. CURRENT CONCEPTS IN THE ETHICAL CONDUCT OF HUMAN ENVIRONMENTAL HEALTH RESEARCH

    Science.gov (United States)

    In recent years, the concern for human research subject protection has increased markedly in the United States. The nature of research subject participation in controlled exposure environmental health research is such that the individual subject bears the risk of participation w...

  6. Creating human organs in chimaera pigs : an ethical source of immunocompatible organs?

    NARCIS (Netherlands)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2015-01-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises

  7. Creating human organs in chimaera pigs : an ethical source of immunocompatible organs?

    NARCIS (Netherlands)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2014-01-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises

  8. Ethical and Legal Considerations in Dental Caries Research Using Human Subjects: Conference Summary.

    Science.gov (United States)

    Jenny, Joanna

    1980-01-01

    Guidelines of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research are discussed. It is concluded that dentistry must not uncritically accept guidelines meant for a broader class of research, that guidelines can be misapplied, and that researchers must educate themselves on the Commission…

  9. Nursing ethics in a developing country

    Directory of Open Access Journals (Sweden)

    Annatjie Botes

    1999-09-01

    Full Text Available Nursing is a true profession, distinguished by its philosophy of care, its full-time commitment to human well being, its particular blend of knowledge and skills and its valuable service to the community (Curtin & Flaherty, 1982:92. Ethics is vital to nursing. Being a professional implies ethical behaviour and knowledge of what it means to be ethical (Pera & Van Tonder, 1996:v. Ethics is the foundation of committed service to humankind. When nurses practice in an ethical manner they should adhere to ethical principles like autonomy, beneficence, justice, veracity, fidelity, confidentiality and privacy.

  10. Conversing on Ethics, Morality and Education

    Science.gov (United States)

    McGavin, P. A.

    2013-01-01

    In philosophical use, "ethics" and "moral philosophy" are more closely synonymous--one deriving from Greek, "ethike" and the other from Latin "moralis." In typical social science paradigms, there generally prevails a consensual sense of contemporary everyday use of "ethics," except where earlier…

  11. The importance of the olfactory sense in the human behavior and evolution.

    Science.gov (United States)

    Sarafoleanu, C; Mella, C; Georgescu, M; Perederco, C

    2009-01-01

    Not long ago it was believed that the human olfactory sense had a low importance, a vision which turned into the exploration of the environment. Recent studies have shown that, despite the weak representation of the olfactory receptor common in other species too, the cortical areas of integration of the olfactory sensations are very large and have important interconnections with memory, language, and neuro-vegetative areas. In humans, olfaction has a small contribution in identifying objects or other people, but plays an important social and emotional part. People learn to love or to hate certain foods or objects only by appreciating their odor and this proved to be a very important economic factor. The most significant role of olfactory signals in humans appears to be the modulation of their behavior and interpersonal relationships, of their affiliation to certain groups or social classes, having a major influence in their tastes and personality. signal that will be sent to the specialized areas in their tastes and personality.

  12. Analyzing and sense making of human factors in the Malaysian radiation and nuclear emergency planning framework

    Science.gov (United States)

    Hamid, A. H. A.; Rozan, M. Z. A.; Deris, S.; Ibrahim, R.; Abdullah, W. S. W.; Rahman, A. A.; Yunus, M. N. M.

    2016-01-01

    The evolution of current Radiation and Nuclear Emergency Planning Framework (RANEPF) simulator emphasizes on the human factors to be analyzed and interpreted according to the stakeholder's tacit and explicit knowledge. These human factor criteria are analyzed and interpreted according to the "sense making theory" and Disaster Emergency Response Management Information System (DERMIS) design premises. These criteria are corroborated by the statistical criteria. In recent findings, there were no differences of distributions among the stakeholders according to gender and organizational expertise. These criteria are incrementally accepted and agreed the research elements indicated in the respective emergency planning frameworks and simulator (i.e. 78.18 to 84.32, p-value human factors criteria in the associated analyses and theoretical perspectives to be further acomodated in the future simulator development. This development is in conjunction with the proposed hypothesis building of the process factors and responses diagram. We proposed that future work which implies the additional functionality of the simulator, as strategized, condensed and concise, comprehensive public disaster preparedness and intervention guidelines, to be a useful and efficient computer simulation.

  13. Analyzing and sense making of human factors in the Malaysian radiation and nuclear emergency planning framework

    Energy Technology Data Exchange (ETDEWEB)

    Hamid, A. H. A., E-mail: amyhamijah@gmail.com, E-mail: amyhamijah@nm.gov.my [Faculty of Computing, Universiti Teknologi Malaysia (UTM), Skudai, 81310 Johor Bahru, Johor (Malaysia); Universiti Malaysia Kelantan (UMK), Pengkalan Chepa, 16100 Kota Bharu, Kelantan (Malaysia); Rozan, M. Z. A., E-mail: drmohdzaidi@gmail.com; Ibrahim, R. [Faculty of Computing, Universiti Teknologi Malaysia (UTM), Skudai, 81310 Johor Bahru, Johor (Malaysia); Deris, S. [Universiti Malaysia Kelantan (UMK), Pengkalan Chepa, 16100 Kota Bharu, Kelantan (Malaysia); Abdullah, W. S. W.; Yunus, M. N. M. [Malaysian Nuclear Agency (NM), Bangi, 43000 Kajang, Selangor (Malaysia); Rahman, A. A. [Faculty of Medicine and Health Sciences, Universiti Putra Malaysia (UPM), 43400 Serdang, Selangor (Malaysia)

    2016-01-22

    The evolution of current Radiation and Nuclear Emergency Planning Framework (RANEPF) simulator emphasizes on the human factors to be analyzed and interpreted according to the stakeholder’s tacit and explicit knowledge. These human factor criteria are analyzed and interpreted according to the “sense making theory” and Disaster Emergency Response Management Information System (DERMIS) design premises. These criteria are corroborated by the statistical criteria. In recent findings, there were no differences of distributions among the stakeholders according to gender and organizational expertise. These criteria are incrementally accepted and agreed the research elements indicated in the respective emergency planning frameworks and simulator (i.e. 78.18 to 84.32, p-value <0.05). This paper suggested these human factors criteria in the associated analyses and theoretical perspectives to be further acomodated in the future simulator development. This development is in conjunction with the proposed hypothesis building of the process factors and responses diagram. We proposed that future work which implies the additional functionality of the simulator, as strategized, condensed and concise, comprehensive public disaster preparedness and intervention guidelines, to be a useful and efficient computer simulation.

  14. Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs.

    Science.gov (United States)

    Quan, S; Yang, L; Abraham, N G; Kappas, A

    2001-10-09

    Our objective was to determine whether overexpression and underexpression of human heme oxygenase (HHO)-1 could be controlled on a long-term basis by introduction of the HO-1 gene in sense (S) and antisense (AS) orientation with an appropriate vector into endothelial cells. Retroviral vector (LXSN) containing viral long terminal repeat promoter-driven human HO-1 S (LSN-HHO-1) and LXSN vectors containing HHO-1 promoter (HOP)-controlled HHO-1 S and AS (LSN-HOP-HHO-1 and LSN-HOP-HHO-1-AS) sequences were constructed and used to transfect rat lung microvessel endothelial cells (RLMV cells) and human dermal microvessel endothelial cells (HMEC-1 cells). RLMV cells transduced with HHO-1 S expressed human HO-1 mRNA and HO-1 protein associated with elevation in total HO activity compared with nontransduced cells. Vector-mediated expression of HHO-1 S or AS under control of HOP resulted in effective production of HO-1 or blocked induction of endogenous human HO-1 in HMEC-1 cells, respectively. Overexpression of HO-1 AS was associated with a long-term decrease (45%) of endogenous HO-1 protein and an increase (167%) in unmetabolized exogenous heme in HMEC-1 cells. Carbon monoxide (CO) production in HO-1 S- or AS-transduced HMEC-1 cells after heme treatment was increased (159%) or decreased (50%), respectively, compared with nontransduced cells. HO-2 protein levels did not change. These findings demonstrate that HHO-1 S and AS retroviral constructs are functional in enhancing and reducing HO activity, respectively, and thus can be used to regulate cellular heme levels, the activity of heme-dependent enzymes, and the rate of heme catabolism to CO and bilirubin.

  15. Climate Blues: or How Awareness of the Human End might re-instil Ethical Purpose to the Writing of History

    Directory of Open Access Journals (Sweden)

    Mark Levene

    2013-05-01

    Full Text Available The accumulating evidence on the depth and accelerating trajectory of anthropogenic climate change poses the possibility of an early end to human existence as part of a more general biotic extinction. But if that is the case what does that mean for the latter day writing of history? Our response follows two main lines of thought. The first relates to the concept of the ‘Anthropocene’ and the possibilities that it offers historians to reconsider their subject in the light of what earth science is saying about earth history and our particularly recent role in its shaping. From this perspective, while the idea of a reconceptualised history by reference to key geological and other natural historical thresholds would certainly destabilise current academic practice, it might equally galvanise the historical discipline towards recognition of our present biospheric crisis. The second line of thought explores how history writing might contribute to an ethical response in the face of the end and an almost inevitable, accompanying violence, anomie and destruction. Apocalyptic language is eschewed by a progress-centred history. Here we argue that it is exactly the proper recovery of such discarded religiously subversive notions which could assist in the opening up of an alternative space repudiating a bankrupt political-economic system and envisioning instead a millennial social and environmental justice. The writings of Walter Benjamin, among others, offer historical pathfinders for such ideas. Combined with his presentation of an alternative, qualitative ‘Now’ time—thereby reconfiguring Judeo-Christian notions of kairos—such ideas speak both to the urgency for a purposeful, non- violent response to Endtime but also by implication, an ongoing human quest for grace.

  16. Seeking an ethical and legal way of procuring transplantable organs from the dying without further attempts to redefine human death

    Directory of Open Access Journals (Sweden)

    Evans David

    2007-06-01

    Full Text Available Abstract Because complex organs taken from unequivocally dead people are not suitable for transplantation, human death has been redefined so that it can be certified at some earlier stage in the dying process and thereby make viable organs available without legal problems. Redefinitions based on concepts of "brain death" have underpinned transplant practice for many years although those concepts have never found universal philosophical acceptance. Neither is there consensus about the clinical tests which have been held sufficient to diagnose the irreversible cessation of all brain function – or as much of it as is deemed relevant – while the body remains alive. For these reasons, the certification of death for transplant purposes on "brain death" grounds is increasingly questioned and there has been pressure to return to its diagnosis on the basis of cardiac arrest and the consequent cessation of blood circulation throughout the body. While superficially a welcome return to the traditional and universally accepted understanding of human death, examination of the protocols using such criteria for the diagnosis of death prior to organ removal reveals a materially different scenario in which the circulatory arrest is not certainly final and purely nominal periods of arrest are required before surgery begins. Recognizing the probably unresolvable conflict between allowing enough time to pass after truly final circulatory arrest for a safe diagnosis of death and its minimization for the sake of the wanted organs, Verheijde and colleagues follow others in calling for the abandonment of the "dead donor rule" and the enactment of legislation to permit the removal of organs from the dying, without pretence that they are dead before that surgery. While it may be doubted whether such a "paradigm change" in the ethics of organ procurement would be accepted by society, their call for its consideration as a fully and fairly informed basis for organ

  17. Political interventions in U.S. human embryo research: an ethical assessment.

    Science.gov (United States)

    Green, Ronald M

    2010-01-01

    For more than 30 years, beginning with the Reagan administration's refusal to support and provide oversight for embryo research, and continuing to the present in congressionally imposed limits on funding for such research, progress in infertility medicine and the development of stem cell therapies has been seriously delayed by a series of political interventions. In almost all cases, these interventions result from a view of the moral status of human embryo premised largely on religious assumptions. Although some believe that these interventions are valid expressions of religious values in the public sector, it is argued here that they, in fact, contradict Rawls's conception of public reasoning. Both the prohibition of research involving the human embryo as well as bans on federal funding for embryo-related research place the particular religious views of some citizens above the pressing health needs of almost all, and thus violate the ideal of civility implicit in the Rawlsian standard.

  18. A new medical research model: ethically and responsibly advancing health for humans and animals.

    Science.gov (United States)

    Olson, Patricia N; Ganzert, Robin R

    2015-01-01

    With the increasing use of genomics, computational analytics, emerging technologies, and personalized medicine, the possibility of a new research model is emerging. Using the clues from thousands of species living on our planet, scientists from many disciplines (medicine, veterinary medicine, wildlife) must collaborate, prioritize, and strategize on how to address causes of health and disease. Such clues should guide disease prevention, as well as the development of innovative, efficacious, and gentler therapies. Geographic and language barriers must be broken down, and scientists--even within a single academic, corporate, or government research site--must be vigilant in seeking the help of nonmedical disciplines of colleagues from whence answers might come. The public will become more interested in and demanding of such a model, desiring that all family members (humans and animals) have an opportunity for a long and healthy life. Above all, such activities will be humanely conducted with outcomes having the greatest chance for success.

  19. The Ethics of Human Life Extension: The Second Argument from Evolution.

    Science.gov (United States)

    Gyngell, Chris

    2015-12-01

    One argument that is sometimes made against pursuing radical forms of human life extension is that such interventions will make the species less evolvable, which would be morally undesirable. In this article, I discuss the empirical and evaluative claims of this argument. I argue that radical increases in life expectancy could, in principle, reduce the evolutionary potential of human populations through both biological and cultural mechanisms. I further argue that if life extension did reduce the evolvability of the species, this will be undesirable for three reasons: (1) it may increase the species' susceptibility to extinction risks, (2) it may adversely affect institutions and practices that promote well-being, and (3) it may impede moral progress.

  20. Ethics and Biosafety in Dental Care for Patients with Human Immunodeficiency Virus

    Directory of Open Access Journals (Sweden)

    Ana Ibis Betancourt García

    2013-02-01

    Full Text Available Background: the only way of contracting human immunodeficiency virus during dental treatment is through contact with the blood of an HIV-positive patient with non-intact skin or mucosa of the professional. This requires biosecurity measures to reduce the risk of crossed infection and ensure compliance of bioethical aspects to be considered when treating these patients. Objective: To determine knowledge levels of dentists on biosafety and bioethical principle of justice in the treatment of patients with human immunodeficiency virus. Methods: A cross sectional and descriptive study was conducted involving 45 professionals who worked in Stomatological clinics of three parishes in Caracas, Venezuela, from January to December 2010. The following were analyzed: knowledge on biosafety (mechanisms of disease transmission, control measures and flowchart sterilization measures before an accident and the justice bioethical principle (time and place of treatment, instruments used and time to devote to patient. Results: The knowledge level according to the bioethical principle of justice was assessed: 40% for good, 37.7% for average and 22.2% for bad. For biosecurity measures it was obtained: 26.6% good, 24.4% average and 48.8% bad. Conclusions: knowledge level on the bioethical principle of justice and biosecurity measures to treat patients living with human immunodeficiency virus is unsatisfactory in more than half of the dentists surveyed.

  1. Two concepts of medical ethics and their implications for medical ethics education.

    Science.gov (United States)

    Rhodes, Rosamond

    2002-08-01

    People who discuss medical ethics or bioethics come to very different conclusions about the levels of agreement in the field and the implications of consensus among health care professionals. In this paper I argue that these disagreements turn on a confusion of two distinct senses of medical ethics. I differentiate (1) medical ethics as a subject in applied ethics from (2) medical ethics as the professional moral commitments of health care professions. I then use the distinction to explain its significant implications for medical ethics education. Drawing on the recent work of John Rawls, I also show the centrality of philosophy in medical ethics by illustrating how contemporary philosophy can be used to construct an ethical framework for the medical professions.

  2. Abortion ethics.

    Science.gov (United States)

    Fromer, M J

    1982-04-01

    Nurses have opinions about abortion, but because they are health professionals and their opinions are sought as such, they are obligated to understand why they hold certain views. Nurses need to be clear about why they believe as they do, and they must arrive at a point of view in a rational and logical manner. To assist nurses in this task, the ethical issues surrounding abortion are enumerated and clarified. To do this, some of the philosophic and historic approaches to abortion and how a position can be logically argued are examined. At the outset some emotion-laden terms are defined. Abortion is defined as the expulsion of a fetus from the uterus before 28 weeks' gestation, the arbitrarily established time of viability. This discussion is concerned only with induced abortion. Since the beginning of recorded history women have chosen to have abortions. Early Jews and Christians forbade abortion on practical and religious grounds. A human life was viewed as valuable, and there was also the practical consideration of the addition of another person to the population, i.e., more brute strength to do the necessary physical work, defend against enemies, and ensure the continuation of the people. These kinds of pragmatic reasons favoring or opposing abortion have little to do with the Western concept of abortion in genaeral and what is going on in the U.S. today in particular. Discussion of the ethics of abortion must rest on 1 or more of several foundations: whether or not the fetus is a human being; the rights of the pregnant woman as opposed to those of the fetus, and circumstances of horror and hardship that might surround a pregnancy. Viability is relative. Because viability is not a specific descriptive entity, value judgments become part of the determination, both of viability and the actions that might be taken based on that determination. The fetus does not become a full human being at viability. That occurs only at conception or birth, depending on one's view

  3. Uncertain translation, uncertain benefit and uncertain risk: ethical challenges facing first-in-human trials of induced pluripotent stem (ips) cells.

    Science.gov (United States)

    Fung, Ronald K F; Kerridge, Ian H

    2013-02-01

    The discovery of induced pluripotent stem (iPS) cells in 2006 was heralded as a major breakthrough in stem cell research. Since then, progress in iPS cell technology has paved the way towards clinical application, particularly cell replacement therapy, which has refueled debate on the ethics of stem cell research. However, much of the discourse has focused on questions of moral status and potentiality, overlooking the ethical issues which are introduced by the clinical testing of iPS cell replacement therapy. First-in-human trials, in particular, raise a number of ethical concerns including informed consent, subject recruitment and harm minimisation as well as the inherent uncertainty and risks which are involved in testing medical procedures on humans for the first time. These issues, while a feature of any human research, become more complex in the case of iPS cell therapy, given the seriousness of the potential risks, the unreliability of available animal models, the vulnerability of the target patient group, and the high stakes of such an intensely public area of science. Our paper will present a detailed case study of iPS cell replacement therapy for Parkinson's disease to highlight these broader ethical and epistemological concerns. If we accept that iPS cell technology is fraught with challenges which go far beyond merely refuting the potentiality of the stem cell line, we conclude that iPS cell research should not replace, but proceed alongside embryonic and adult somatic stem cell research to promote cross-fertilisation of knowledge and better clinical outcomes.

  4. Nonviolent communication: a dialogical retrieval of the ethic of authenticity.

    Science.gov (United States)

    Nosek, Marcianna

    2012-11-01

    Charles Taylor called for a retrieval of the ethic of authenticity that has been distorted in modern notions of autonomy and self-fulfillment. Via exchanges with others who matter to us, he proposed that human identities develop through the use of rich language draped in shared horizons of significance. The fostering of these dialogical ties beyond purely instrumental purposes, along with the recognition of the human dignity in all, may avert the fallen ideal of authenticity. Nonviolent communication affords the skillful dialogue with others cradled in a shared sense of significance and supports the development of a meaningful identity-one that is formed through the realization of what exists beyond the self. The purpose of this article is to argue that nonviolent communication facilitates the retrieval of the ethic of authenticity. Narratives from nursing students' journals on the use of nonviolent communication skills will be used to support the argument.

  5. 近代情感主义伦理学道德探析%On the ethics of modern emotional ethics

    Institute of Scientific and Technical Information of China (English)

    杜润洲

    2016-01-01

    十七世纪英国经验主义伦理学是与欧洲大陆理性主义伦理学不断争论中发展起来的,从最初的理性主义逐渐向情感主义转化,观点的转变首先体现在对道德感的重视,注重对人心理和道德感的研究。本文前人对伦理学研究的基础上,对近代情感主义伦理学中的道德进行探析。%In the seventeenth Century the British empiricist ethics is developed with the continent rationalism ethics controversy in the initial gradually from rationalism to emotionalism translate, viewpoint change is reflected in the importance of moral sense, paying attention to the research of human psychology and moral sense. On the basis of the research of ethics, this article is to probe into the ethics of modern emotional ethics.

  6. Intelligence Ethics:

    DEFF Research Database (Denmark)

    Rønn, Kira Vrist

    2016-01-01

    Questions concerning what constitutes a morally justified conduct of intelligence activities have received increased attention in recent decades. However, intelligence ethics is not yet homogeneous or embedded as a solid research field. The aim of this article is to sketch the state of the art...... of intelligence ethics and point out subjects for further scrutiny in future research. The review clusters the literature on intelligence ethics into two groups: respectively, contributions on external topics (i.e., the accountability of and the public trust in intelligence agencies) and internal topics (i.......e., the search for an ideal ethical framework for intelligence actions). The article concludes that there are many holes to fill for future studies on intelligence ethics both in external and internal discussions. Thus, the article is an invitation – especially, to moral philosophers and political theorists...

  7. Evaluative profiling of arsenic sensing and regulatory systems in the human microbiome project genomes.

    Science.gov (United States)

    Isokpehi, Raphael D; Udensi, Udensi K; Simmons, Shaneka S; Hollman, Antoinesha L; Cain, Antia E; Olofinsae, Samson A; Hassan, Oluwabukola A; Kashim, Zainab A; Enejoh, Ojochenemi A; Fasesan, Deborah E; Nashiru, Oyekanmi

    2014-01-01

    The influence of environmental chemicals including arsenic, a type 1 carcinogen, on the composition and function of the human-associated microbiota is of significance in human health and disease. We have developed a suite of bioinformatics and visual analytics methods to evaluate the availability (presence or absence) and abundance of functional annotations in a microbial genome for seven Pfam protein families: As(III)-responsive transcriptional repressor (ArsR), anion-transporting ATPase (ArsA), arsenical pump membrane protein (ArsB), arsenate reductase (ArsC), arsenical resistance operon transacting repressor (ArsD), water/glycerol transport protein (aquaporins), and universal stress protein (USP). These genes encode function for sensing and/or regulating arsenic content in the bacterial cell. The evaluative profiling strategy was applied to 3,274 genomes from which 62 genomes from 18 genera were identified to contain genes for the seven protein families. Our list included 12 genomes in the Human Microbiome Project (HMP) from the following genera: Citrobacter, Escherichia, Lactobacillus, Providencia, Rhodococcus, and Staphylococcus. Gene neighborhood analysis of the arsenic resistance operon in the genome of Bacteroides thetaiotaomicron VPI-5482, a human gut symbiont, revealed the adjacent arrangement of genes for arsenite binding/transfer (ArsD) and cytochrome c biosynthesis (DsbD_2). Visual analytics facilitated evaluation of protein annotations in 367 genomes in the phylum Bacteroidetes identified multiple genomes in which genes for ArsD and DsbD_2 were adjacently arranged. Cytochrome c, produced by a posttranslational process, consists of heme-containing proteins important for cellular energy production and signaling. Further research is desired to elucidate arsenic resistance and arsenic-mediated cellular energy production in the Bacteroidetes.

  8. Involvement of the calcium-sensing receptor in human taste perception.

    Science.gov (United States)

    Ohsu, Takeaki; Amino, Yusuke; Nagasaki, Hiroaki; Yamanaka, Tomohiko; Takeshita, Sen; Hatanaka, Toshihiro; Maruyama, Yutaka; Miyamura, Naohiro; Eto, Yuzuru

    2010-01-08

    By human sensory analyses, we found that various extracellular calcium-sensing receptor (CaSR) agonists enhance sweet, salty, and umami tastes, although they have no taste themselves. These characteristics are known as "kokumi taste" and often appear in traditional Japanese cuisine. Although GSH is a typical kokumi taste substance (taste enhancer), its mode of action is poorly understood. Here, we demonstrate how the kokumi taste is enhanced by the CaSR, a close relative of the class C G-protein-coupled receptors T1R1, T1R2, and T1R3 (sweet and umami receptors). We identified a large number of CaSR agonist gamma-glutamyl peptides, including GSH (gamma-Glu-Cys-Gly) and gamma-Glu-Val-Gly, and showed that these peptides elicit the kokumi taste. Further analyses revealed that some known CaSR agonists such as Ca(2+), protamine, polylysine, L-histidine, and cinacalcet (a calcium-mimetic drug) also elicit the kokumi taste and that the CaSR-specific antagonist, NPS-2143, significantly suppresses the kokumi taste. This is the first report indicating a distinct function of the CaSR in human taste perception.

  9. Accelerated diffusion spectrum imaging via compressed sensing for the human connectome project

    Science.gov (United States)

    Lee, Namgyun; Wilkins, Bryce; Singh, Manbir

    2012-02-01

    Diffusion Spectrum Imaging (DSI) has been developed as a model-free approach to solving the so called multiple-fibers-per- voxel problem in diffusion MRI. However, inferring heterogeneous microstructures of an imaging voxel rapidly remains a challenge in DSI because of extensive sampling requirements in a Cartesian grid of q-space. In this study, we propose compressed sensing based diffusion spectrum imaging (CS-DSI) to significantly reduce the number of diffusion measurements required for accurate estimation of fiber orientations. This method reconstructs each diffusion propagator of an MR data set from 100 variable density undersampled diffusion measurements minimizing the l1-norm of the finite-differences (i.e.,anisotropic total variation) of the diffusion propagator. The proposed method is validated against a ground truth from synthetic data mimicking the FiberCup phantom, demonstrating the robustness of CS-DSI on accurately estimating underlying fiber orientations from noisy diffusion data. We demonstrate the effectiveness of our CS-DSI method on a human brain dataset acquired from a clinical scanner without specialized pulse sequences. Estimated ODFs from CS-DSI method are qualitatively compared to those from the full dataset (DSI203). Lastly, we demonstrate that streamline tractography based on our CS-DSI method has a comparable quality to conventional DSI203. This illustrates the feasibility of CS-DSI for reconstructing whole brain white-matter fiber tractography from clinical data acquired at imaging centers, including hospitals, for human brain connectivity studies.

  10. Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production by Saccharomyces cerevisiae.

    Science.gov (United States)

    Martínez, José L; Liu, Lifang; Petranovic, Dina; Nielsen, Jens

    2015-01-01

    Efficient production of appropriate oxygen carriers for transfusions (blood substitutes or artificial blood) has been pursued for many decades, and to date several strategies have been used, from synthetic polymers to cell-free hemoglobin carriers. The recent advances in the field of metabolic engineering also allowed the generation of different genetically modified organisms for the production of recombinant human hemoglobin. Several studies have showed very promising results using the bacterium Escherichia coli as a production platform, reporting hemoglobin titers above 5% of the total cell protein content. However, there are still certain limitations regarding the protein stability and functionality of the recombinant hemoglobin produced in bacterial systems. In order to overcome these limitations, yeast systems have been proposed as the eukaryal alternative. We recently reported the generation of a set of plasmids to produce functional human hemoglobin in Saccharomyces cerevisiae, with final titers of active hemoglobin exceeding 4% of the total cell protein. In this study, we propose a strategy for further engineering S. cerevisiae by altering the oxygen sensing pathway by deleting the transcription factor HAP1, which resulted in an increase of the final recombinant active hemoglobin titer exceeding 7% of the total cellular protein.

  11. Quorum sensing communication between bacteria and human cells: signals, targets and functions

    Directory of Open Access Journals (Sweden)

    Angelika eHolm

    2014-06-01

    Full Text Available Both direct and long-range interactions between pathogenic Pseudomonas aeruginosa bacteria and their eukaryotic hosts are important in the outcome of infections. For cell-to-cell communication, these bacteria employ the quorum sensing (QS system to pass on information of the density of the bacterial population and collectively switch on virulence factor production, biofilm formation and resistance development. Thus, QS allows bacteria to behave as a community to perform tasks which would be impossible for individual cells, e.g. to overcome defense and immune systems and establish infections in higher organisms. This review highlights these aspects of QS and our own recent research on how P.aeruginosa communicates with human cells using the small QS signal molecules N-acyl homoserine lactones (AHL. We focus on how this conversation changes the behavior and function of neutrophils, macrophages and epithelial cells and on how the signaling machinery in human cells responsible for the recognition of AHL. Understanding the bacteria-host relationships at both cellular and molecular levels is essential for the identification of new targets and for the development of novel strategies to fight bacterial infections in the future.

  12. Solonamide B inhibits quorum sensing and reduces Staphylococcus aureus mediated killing of human neutrophils.

    Science.gov (United States)

    Nielsen, Anita; Månsson, Maria; Bojer, Martin S; Gram, Lone; Larsen, Thomas O; Novick, Richard P; Frees, Dorte; Frøkiær, Hanne; Ingmer, Hanne

    2014-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) continues to be a serious human pathogen, and particularly the spread of community associated (CA)-MRSA strains such as USA300 is a concern, as these strains can cause severe infections in otherwise healthy adults. Recently, we reported that a cyclodepsipeptide termed Solonamide B isolated from the marine bacterium, Photobacterium halotolerans strongly reduces expression of RNAIII, the effector molecule of the agr quorum sensing system. Here we show that Solonamide B interferes with the binding of S. aureus autoinducing peptides (AIPs) to sensor histidine kinase, AgrC, of the agr two-component system. The hypervirulence of USA300 has been linked to increased expression of central virulence factors like α-hemolysin and the phenol soluble modulins (PSMs). Importantly, in strain USA300 Solonamide B dramatically reduced the activity of α-hemolysin and the transcription of psma encoding PSMs with an 80% reduction in toxicity of supernatants towards human neutrophils and rabbit erythrocytes. To our knowledge this is the first report of a compound produced naturally by a Gram-negative marine bacterium that interferes with agr and affects both RNAIII and AgrA controlled virulence gene expression in S. aureus.

  13. MSV3d: database of human MisSense Variants mapped to 3D protein structure.

    Science.gov (United States)

    Luu, Tien-Dao; Rusu, Alin-Mihai; Walter, Vincent; Ripp, Raymond; Moulinier, Luc; Muller, Jean; Toursel, Thierry; Thompson, Julie D; Poch, Olivier; Nguyen, Hoan

    2012-01-01

    The elucidation of the complex relationships linking genotypic and phenotypic variations to protein structure is a major challenge in the post-genomic era. We present MSV3d (Database of human MisSense Variants mapped to 3D protein structure), a new database that contains detailed annotation of missense variants of all human proteins (20 199 proteins). The multi-level characterization includes details of the physico-chemical changes induced by amino acid modification, as well as information related to the conservation of the mutated residue and its position relative to functional features in the available or predicted 3D model. Major releases of the database are automatically generated and updated regularly in line with the dbSNP (database of Single Nucleotide Polymorphism) and SwissVar releases, by exploiting the extensive Décrypthon computational grid resources. The database (http://decrypthon.igbmc.fr/msv3d) is easily accessible through a simple web interface coupled to a powerful query engine and a standard web service. The content is completely or partially downloadable in XML or flat file formats. Database URL: http://decrypthon.igbmc.fr/msv3d.

  14. 克隆人技术伦理根基之思考%Considerations on the Ethical Foundations of Human Cloning Technology

    Institute of Scientific and Technical Information of China (English)

    季爱民

    2014-01-01

    From the purpose of human cloning technology ,basic research of cloning generally does not cause a strong impact on the ethical issues ,while therapeutic and reproductive cloning really do .The ethical issues of reproductive cloning is especially detrimental to human dignity ,w hile the core of the ethical issues on therapeutic cloning is the rights and moral status of the embryonic .Taking the two property of truth and practice of human cloning technology into consideration ,as well as the relative criteria ,absolutely good or bad judge on the technology is not rigorous .However ,it is necessary to formulate ethical principles that regulate the technology field on bioethics .Among them ,the principle of informed consent is supposed to be an important one ,the ethics basis of w hich is :human being is ends ,not means .%从克隆人技术目的看,基础研究性克隆一般不会引起伦理上强烈冲击,治疗性和生殖性克隆则强烈冲击着人类伦理道德。生殖性克隆伦理问题的突出表现在于有损人类的尊严,治疗性克隆伦理问题的核心则是胚胎的权利与道德地位问题。考虑到克隆人技术的真理性和实践性两个层面,以及评判标准的相对性,对该技术进行绝对的善恶评判有失慎重。不过,生命伦理领域制定规范该技术的伦理原则是必须的,其中,知情同意原则理应是一个重要原则,其伦理学依据在于:人是目的,而不是手段。

  15. Ethical issues in research.

    Science.gov (United States)

    Artal, Raul; Rubenfeld, Sheldon

    2017-08-01

    Biomedical research is currently guided by ethical standards that have evolved over many centuries. Historical and political events, social and legal considerations, and continuous medical and technological advances have led to the prevailing research ethics and practice. Currently, patients and research subjects have complete autonomy while under medical care or when volunteering as research subjects. Enrolling volunteers in human subjects research includes a detailed and meaningful informed consent process that follows the cardinal principles of ethics: autonomy, beneficence, nonmaleficence, and justice. These principles were gradually adopted after World War II, primarily in response to the unethical behavior of German physicians and scientists during the Third Reich. This review emphasizes the importance of historical milestones and the essential role that ethics has in contemporary medical research. Research protocols should achieve maximum benefits for the society, have clinical and scientific value, be subject to independent review, respect human dignity, and follow the principles of informed consent, and most importantly, subjects should have complete autonomy. However, current principles and regulations cannot cover every conceivable situation, particularly in view of the new advances in science and technology. New and evolving medical technology, genetic research, therapeutic interventions, and innovations challenge society to maintain the highest moral and ethical principles. Copyright © 2017. Published by Elsevier Ltd.

  16. Toward an Ideal Relational Ethic: Rethinking university-community engagement

    Directory of Open Access Journals (Sweden)

    Steve Garlick

    2008-09-01

    Full Text Available This paper explores how an ideal relational ethic based on Zygmunt Bauman’s (1995 notion of forms of togetherness is needed to underpin university-community engagement processes and practices. We focus on the notion of being-for, and suggest that it can be used as an ‘engagement bridge’ between higher education institutions, the creation of human capital and communities, and can be a means to achieve ethical outcomes to local concerns. Much of Bauman’s (1995; 2001; 2007 theoretical development has focussed on the liquidity of modernity, to give the impression that community - in the spatially, physically located and fixed sense of the term - no longer exists. This paper proposes that spatial dimensions, particularly in the context of developing relational ethics, are important. This is particularly so for paying adequate attention to context-specific values, principles and issues in communities, for developing enterprising human capital via engagement, and for addressing matters of socio-political importance such as the environment. Contemporary neo-liberal times require ethical and moral leadership from universities. This paper suggests that such leadership can be developed from focussing attention on the forms of togetherness fostered by university-community engagement.

  17. Limb position sense, proprioceptive drift and muscle thixotropy at the human elbow joint.

    Science.gov (United States)

    Tsay, A; Savage, G; Allen, T J; Proske, U

    2014-06-15

    These experiments on the human forearm are based on the hypothesis that drift in the perceived position of a limb over time can be explained by receptor adaptation. Limb position sense was measured in 39 blindfolded subjects using a forearm-matching task. A property of muscle, its thixotropy, a contraction history-dependent passive stiffness, was exploited to place muscle receptors of elbow muscles in a defined state. After the arm had been held flexed and elbow flexors contracted, we observed time-dependent changes in the perceived position of the reference arm by an average of 2.8° in the direction of elbow flexion over 30 s (Experiment 1). The direction of the drift reversed after the arm had been extended and elbow extensors contracted, with a mean shift of 3.5° over 30 s in the direction of elbow extension (Experiment 2). The time-dependent changes could be abolished by conditioning elbow flexors and extensors in the reference arm at the test angle, although this led to large position errors during matching (±10°), depending on how the indicator arm had been conditioned (Experiments 3 and 4). When slack was introduced in the elbow muscles of both arms, by shortening muscles after the conditioning contraction, matching errors became small and there was no drift in position sense (Experiments 5 and 6). These experiments argue for a receptor-based mechanism for proprioceptive drift and suggest that to align the two forearms, the brain monitors the difference between the afferent signals from the two arms.

  18. Ethical Issues in Human Stem Cell Research%干细胞研究及其伦理学问题

    Institute of Scientific and Technical Information of China (English)

    翟晓梅

    2001-01-01

    The stem cell is a unique and essential cell type found in animals.When stem cells divide, some of the progeny mature into cells of a specific type , while others remain stem cells, ready to repair some of the everyday wear and tear undergone by our bodies. These stem cells are capable of continually reproducing themselves and serve to renew tissue throughout an individual's life. The most fundamental and extraordinary of the stem cells are found in the early-stage embryo. Scientific reports of the successful isolation and culture of the stem cells have offered hope of new cures for debilitating and even fatal illness, while at the same time renewing an important debate about the ethics of research involving human embryos and cadaveric fetal material.%干细胞是动物体内一种独特的基本细胞类型。干细胞分化时,有些成为特殊类型的细胞,另一些仍维持干细胞,准备替代机体衰老和损伤的细胞。这些干细胞本身能够复制,以供机体终生组织更新的需要。最基本的多能干细胞存在于早期胚胎中。科学家们成功分离和培育干细胞的报告,为退行性疾病和损伤甚至致命性疾病的治疗带来了新的希望。然而,与此同时也引起了世界范围的关于使用人类胚胎和死亡胎儿进行研究的伦理大争论。

  19. Just another reproductive technology? The ethics of human reproductive cloning as an experimental medical procedure.

    Science.gov (United States)

    Elsner, D

    2006-10-01

    Human reproductive cloning (HRC) has not yet resulted in any live births. There has been widespread condemnation of the practice in both the scientific world and the public sphere, and many countries explicitly outlaw the practice. Concerns about the procedure range from uncertainties about its physical safety to questions about the psychological well-being of clones. Yet, key aspects such as the philosophical implications of harm to future entities and a comparison with established reproductive technologies such as in vitro fertilisation (IVF) are often overlooked in discussions about HRC. Furthermore, there are people who are willing to use the technology. Several scientists have been outspoken in their intent to pursue HRC. The importance of concerns about the physical safety of children created by HRC and comparisons with concerns about the safety of IVF are discussed. A model to be used to determine when it is acceptable to use HRC and other new assisted reproductive technologies, balancing reproductive freedom and safety concerns, is proposed. Justifications underpinning potential applications of HRC are discussed, and it is determined that these are highly analogous to rationalisations used to justify IVF treatment. It is concluded that people wishing to conceive using HRC should have a prima facie negative right to do so.

  20. Values and Environmental Ethics – Pillars of Changing Human Behaviour Toward Sustainable Development

    Directory of Open Access Journals (Sweden)

    Florina Bran

    2013-02-01

    Full Text Available Sustainable development necessitates the harmonisation of human’s and nature’s needs under the siege of continuous demographic growth and the quest for wellbeing based on material things. This outcome implies important changes to occur at individual, collective and corporate behaviour. How they could be accomplished is a question that animates debates for several decades and revealed that solutions should be related to the process of valuation. Better understanding of value and how it relates to the needs of environmental protection is the aim of our analysis that recalls axiological milestones and compares them with environment related issues. Value as a product of object and subject in the framework of human aspirations is at some extent transposed in economic value. Environmental goods valuation in economic terms encounters numerous difficulties, including high costs and low reliability. Therefore we conclude that decision making should be underpinned not only by economic valuation, but also by value judgement that cannot be expressed in monetary terms.