TIC pour un accès équitable aux ressources humaines en sante en ...

International Development Research Centre (IDRC) Digital Library (Canada)

Ce projet vise à mieux comprendre comment les TIC peuvent faciliter la distribution équitable des ressources humaines en santé en renforçant et consolidant des activités ... Technologies de l'Information et de la Communication (TIC) pour un Accès équitable aux Ressources Humaines en santé qualifiées, motivées et bien ...

A Sandbox Environment for the CSM Standard and SPICE

Science.gov (United States)

Hare, T. M.; Laura, J. R.

2018-04-01

We present ongoing work USGS is undertaking to provide a programming environment for the Camera Sensor Model (CSM) standard and associated SPICE information. This allows for instrument testing and experimentation outside a given production area.

Des relations plus humaines ?

OpenAIRE

Ricciardi, Ferruccio

2013-01-01

À partir d’une approche sociohistorique, cet article s’intéresse aux effets de la croissance économique sur l’identité des cadres, en l’occurrence les groupements de cadres et patrons italiens qui, au lendemain de la Seconde Guerre mondiale, essaient de conjuguer les principes du catholicisme social dont ils se réclament dans l’arène publique avec les logiques issues du productivisme managérial américain qui s’impose en Europe occidentale. Le prisme des méthodes de « relations humaines » pour...

Coordonnateur, (h/f) Ressources humaines | CRDI - Centre de ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sous la direction de directrice des ressources humaines, le coordonnateur, ... est le principal responsable de la gestion des dossiers papier et électroniques de la ... ordre de priorité, tenir l'emploi du temps à jour, gérer un système de contrôle, ...

Inhibition of Pseudomonas aeruginosa virulence: characterization of the AprA-AprI interface and species selectivity.

Science.gov (United States)

Bardoel, Bart W; van Kessel, Kok P M; van Strijp, Jos A G; Milder, Fin J

2012-01-20

Pseudomonas aeruginosa secretes the virulence factor alkaline protease (AprA) to enhance its survival. AprA cleaves one of the key microbial recognition molecules, monomeric flagellin, and thereby diminishes Toll-like receptor 5 activation. In addition, AprA degrades host proteins such as complement proteins and cytokines. P. aeruginosa encodes a highly potent inhibitor of alkaline protease (AprI) that is solely located in the periplasm where it is presumed to protect periplasmic proteins against secreted AprA. We set out to study the enzyme-inhibitor interactions in more detail in order to provide a basis for future drug development. Structural and mutational studies reveal that the conserved N-terminal residues of AprI occupy the protease active site and are essential for inhibitory activity. We constructed peptides mimicking the N-terminus of AprI; however, these were incapable of inhibiting AprA-mediated flagellin cleavage. Furthermore, we expressed and purified AprI of P. aeruginosa and the homologous (37% sequence identity) AprI of Pseudomonas syringae, which remarkably show species specificity for their cognate protease. Exchange of the first five N-terminal residues between AprI of P. syringae and P. aeruginosa did not affect the observed specificity, whereas exchange of only six residues located at the AprI surface that contacts the protease did abolish specificity. These findings are elementary steps toward the design of molecules derived from the natural inhibitor of the virulence factor AprA and their use in therapeutic applications in Pseudomonas and other Gram-negative infections. Copyright © 2011 Elsevier Ltd. All rights reserved.

Les humains sont-ils des entités matérielles ?

Directory of Open Access Journals (Sweden)

Tauveron Matthias

2012-07-01

Full Text Available Nous étudions la sémantique des noms d’humains dans le lexique français. Dans la littérature, ces noms ont un positionnement indéterminé ou ambigu par rapport au critère concret/abstrait. Ce fait est regrettable car ce critère est considéré comme fondamental. Nous montrons leur positionnement particulier vis-à-vis de ce critère au travers de l’étude de métaphores attestées en corpus dans divers textes écrits. Nous suivons l’optique de Lakoff et Johnson en considérant que la métaphore est un révélateur des catégories de pensée. Dans cet esprit, la question est de savoir si les humains sont des entités matérielles ou non. L’étude est menée sur deux paramètres définitoires des entités matérielles : la masse et la spatialité. Nous apportons des caractérisations lexicales de ces deux propriétés. La masse est envisagée généralement, autour des noms, adjectifs et verbes relevés dans les dictionnaires. Nous proposons une synthèse des divers paramètres dénotant la spatialité dans la littérature, sous la forme de six points indépendants (forme, intérieur/extérieur, sous-parties, changement de posture, localisation, déplacement. L’étude de la spatialité est menée systématiquement dans ces directions grâce à des tests issus des caractérisations lexicales de ces aspects. Les tests font voir que, si les humains sont dotés d’une certaine dimension matérielle (qu’ils partagent ainsi avec les objets concrets, ils ont également au moins trois autres dimensions qui font qu’ils ne se réduisent pas à des objets matériels. Nous montrons ainsi que l’humain est, dans le lexique français, doté d’une multiplicité ontologique : en plus d’une dimension matérielle, il dispose d’une dimension psychologique, une dimension praxéologique et une dimension sociale. De plus, l’étude des métaphores montre que la dimension matérielle est souvent réduite voire anéantie par rapport aux

The effect of gamma radiation on the ageing of sulfur cured nr/csm and nbr/csm rubber blends reinforced by carbon black

Directory of Open Access Journals (Sweden)

Gordana Marković

2009-10-01

Full Text Available In this work the effect of the γ-radiation dose on ageing of carbon black reinforced elastomeric materials was studied. The compounds based on natural rubber/chlorosulfonated rubber blend (NR/CSM and butadiene acrylonitrile rubber/chlorosulfonated rubber blend (NBR/CSM (50:50, w/w with different loadings (0, 20, 40, 50, 60, 80 and 100 phr of the filler with the average particle size of 40 nm were cured by sulfur. The obtained elastomeric composites were subjected to radiation doses (100, 200, 300 and 400 kGy in the presence of oxygen. The changes of material mechanical properties were estimated after radiation accelerated ageing. By using Fourier transform infrared measurements (ATR-FTIR it was assessed that after exposure to doses of 100 kGy alcohols, ethers, lactones, anhydrides, esters and carboxylic acids are formed in materials. The formation of shorter polyene sequences and aromatic rings in aged samples are assumed on the basis of the obtained spectra.

Analyse du capital humain : diagnostic des dépenses d'éducation au Sénégal

OpenAIRE

Youssouph Ba

2011-01-01

Le but de notre travail consistait dans un premier temps à revisiter les soubassements théoriques du capital humain et savoir si l'augmentation du capital humain a un effet ponctuel sur la croissance économique (aussi bien dans la sphère des pays industrialisés que dans celle des pays en développement). Dans un second temps, il consistait à mesurer la politique du Sénégal en terme de capital humain : mesurer les efforts de financement de l'éducation d'une part et d'autre part, voir si ces eff...

L'infection a virus de l'Immunodeficience Humaine (VIH), facteur ...

African Journals Online (AJOL)

L'infection a virus de l'Immunodeficience Humaine (VIH), facteur predictif de gravite et de mortalite des accidents vasculaires cerebraux au Centre National Hospitalier et Universitaire-Hubert Koutoukou Maga (CNHU-HKM) de Cotonou, Benin.

Distribution des Glossines vecteurs de la Trypanosomose humaine ...

African Journals Online (AJOL)

SARAH

28 févr. 2015 ... RESUME. Objectifs : Dans le but de connaitre la densité apparente et la composition spécifique des glossines dans un ancien foyer de la Trypanosome humaine africaine au Gabon, une enquête entomologique a été menée dans deux biotopes du Parc National de Moukalaba Doudou (Sud Gabon) : le ...

Respirators: APR Issuer Self Study 33461

Energy Technology Data Exchange (ETDEWEB)

Chochoms, Michael [Los Alamos National Laboratory

2016-07-13

Respirators: APR Issuer Self-Study (course 33461) is designed to introduce and familiarize employees selected as air-purifying respirator (APR) issuers at Los Alamos National Laboratory (LANL) with the responsibilities, limitations, procedures, and resources for issuing APRs at LANL. The goal is to enable these issuers to consistently provide proper, functioning APRs to authorized users

Capital humain et croissance : Evidences sur les données de pays Africains

OpenAIRE

Dorothée Boccanfuso; Luc Savard; Bernice E. Savy

2009-01-01

La théorie économique a pendant longtemps admis une relation positive entre le capital humain et la croissance économique (Smith, 1776 ; Becker, 1964) qui sera remise en cause à la fin des années 90 dans plusieurs études (Caselli et al., 1996 ; Pritchett, 2001). Parmi les faiblesses identifiées par ces auteurs, la critique relative à l’utilisation du nombre moyen d’années d’étude comme proxy utilisé pour évaluer le stock de capital humain est souvent avancée. La non prise en considération des...

CAPITAL HUMAIN, EDUCATION ET CROISSANCE ÉCONOMIQUE Une approche économétrique

OpenAIRE

REZINE, Okacha

2015-01-01

Cette recherche examine le lien entre capital humain/éducation et croissance. On s’interroge, en particulier, sur les fondements théoriques de cette relation et sur la manière de la tester. Cette relation est testée sur un panel cylindré comprenant 31 pays africains et, sur la période 1965-2010. La première approche est consacrée à l’analyse des modèles de croissance endogène avec modèle de SOLOW (1956) sans et avec la prise de proxy du capital humain/éducation. Dans la deuxième approche o...

Les sciences cognitives ne sont pas des sciences humaines

Directory of Open Access Journals (Sweden)

Albert Ogien

2011-10-01

Full Text Available Cet article analyse les limites du naturalisme social que Laurence Kaufman et Laurent Cordonier proposent d’adopter dans cette même revue, en critiquant leur plaidoyer pour l’intégration des savoirs des sciences cognitives et des sciences humaines et sociales. Cette critique repose sur la réfutation de trois idées soutenues par les auteurs : 1 la description scientifique des mécanismes cognitifs élémentaires fournit une explication causale des conduites sociales qui doit se substituer à celles des sciences humaines et sociales ; 2 le recours au naturalisme permet de falsifier les préconceptions que ces dernières continuent à entretenir ; 3 le programme de naturalisation de l’esprit n’implique aucune forme de réductionnisme. Cette triple critique permet de rejeter leur appel en faveur d’un modèle intégré de la conduite humaine, en avançant un constat : dans la mesure où on ne sait pas comment combler le hiatus qui sépare les descriptions détaillées du cerveau au travail de l’explication des conduites des individus et de la manière dont ils en assurent la coordination dans le temps même où ils agissent en commun, les sciences humaines et sociales ont peu de choses à aller glaner du côté des sciences cognitives pour améliorer la manière dont elles analysent l’action. C’est que le travail de celles-ci se situe soit au niveau infra-humain du fonctionnement moléculaire, soit au niveau supra-humain de l’évolution ; et que seules les sciences humaines et sociales placent leurs analyses à un niveau simplement humain, en faisant des individus tels qu’ils vivent ensemble la mesure de toutes les choses qui les concernent. Ce qu’elles ne peuvent faire sur un mode naturaliste.Cognitive sciences are not social sciencesThis article examines the limits of the social naturalism proposed by Laurence Kauffman and Laurent Cordonier in this journal by criticizing their plea concerning knowledge integration of

Cost/CYP: a bottom line that helps keep CSM projects cost-efficient.

Science.gov (United States)

1985-01-01

In contraceptive social marketing (CSM), the objective is social good, but project managers also need to run a tight ship, trimming costs, allocating scarce funds, and monitoring their program's progress. 1 way CSM managers remain cost-conscious is through the concept of couple-years-of-protection (CYP). Devised 2 decades ago as an administrative tool to compare the effects of different contraceptive methods, CYP's uses have multiplied to include assessing program output and cost effectiveness. Some of the factors affecting cost/CYP are a project's age, sales volume, management efficiency, and product prices and line. These factors are interconnected. The cost/CYP figures given here do not include outlays for commodities. While the Agency for International Development's commodity costs alter slightly with each new purchase contrast, the agency reports that a condom costs about 4 cents (US), an oral contraceptive (OC) cycle about 12 cents, and a spermicidal tablet about 7 cents. CSM projects have relatively high start-up costs. Within a project's first 2 years, expenses must cover such marketing activities as research, packaging, warehousing, and heavy promotion. As a project ages, sales should grow, producing revenues that gradually amortize these initial costs. The Nepal CSM project provides an example of how cost/CYP can improve as a program ages. In 1978, the year sales began, the project's cost/CYP was about $84. For some time the project struggled to get its products to its target market and gradually overcome several major hurdles. The acquisition of jeeps eased distribution and, by adding another condom brand, sales were increased still more, bringing the cost/CYP down to $8.30 in 1981. With further sales increases and resulting revenues, the cost/CYP dropped to just over $7 in 1983. When the sales volume becomes large enough, CSM projects can achieve economies of scale, which greatly improves cost-efficiency. Fixed costs shrink as a proportion of total

Assessment and correction of BCC_CSM's performance in capturing leading modes of summer precipitation over North Asia

KAUST Repository

Gong, Zhiqiang

2017-11-07

This article examines the ability of Beijing Climate Center Climate System Model (BCC_CSM) in demonstrating the prediction accuracy and the leading modes of the summer precipitation over North Asia (NA). A dynamic-statistic combined approach for improving the prediction accuracy and the prediction of the leading modes of the summer precipitation over NA is proposed. Our results show that the BCC_CSM can capture part of the spatial anomaly features of the first two leading modes of NA summer precipitation. Moreover, BCC_CSM regains relationships such that the first and second mode of the empirical orthogonal function (EOF1 and EOF2) of NA summer precipitation, respectively, corresponds to the development of the El Niño and La Niña conditions in the tropical East Pacific. Nevertheless, BCC_CSM exhibits limited prediction skill over most part of NA and presents a deficiency in reproducing the EOF1\\'s and EOF2\\'s spatial pattern over central NA and EOF2\\'s interannual variability. This can be attributed as the possible reasons why the model is unable to capture the correct relationships among the basic climate elements over the central NA, lacks in its ability to reproduce a consistent zonal atmospheric pattern over NA, and has bias in predicting the relevant Sea Surface Temperature (SST) modes over the tropical Pacific and Indian Ocean regions. Based on the proposed dynamic-statistic combined correction approach, compared with the leading modes of BCC_CSM\\'s original prediction, anomaly correlation coefficients of corrected EOF1/EOF2 with the tropical Indian Ocean SST are improved from 0.18/0.36 to 0.51/0.62. Hence, the proposed correction approach suggests that the BCC_CSM\\'s prediction skill for the summer precipitation prediction over NA and its ability to capture the dominant modes could be certainly improved by choosing proper historical analogue information.

2183-IJBCS-Article-Bouet Alphonse

African Journals Online (AJOL)

hp

Short Communication http://indexmedicus.afro.who.int. Impact de la surveillance humaine sur les dégâts d'oiseaux en riziculture pluviale. Alphonse BOUET 1* ..... dès le lever du soleil pour rejoindre leurs refuges après le coucher du soleil. Il faut par ailleurs une ressource humaine suffisante pour mieux quadriller le champ.

Nephrolepis biserrata, une Ptéridophyte utilisée comme plante ...

African Journals Online (AJOL)

SARAH

30 sept. 2014 ... Extraction des épines de palmiers du corps humain : Dans la réalisation des activités humaines. (entretien des plantations de palmiers à huile, chasse, etc.), les accidents liés aux piquants des feuilles de palmiers sont courants. Pour extraire les restes d'organes de cette plante du corps après ces.

The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence.

Science.gov (United States)

Uzunova, Sonya Dimitrova; Zarkov, Alexander Stefanov; Ivanova, Anna Marianova; Stoynov, Stoyno Stefanov; Nedelcheva-Veleva, Marina Nedelcheva

2014-01-01

The S-phase checkpoint aims to prevent cells from generation of extensive single-stranded DNA that predisposes to genome instability. The S. cerevisiae complex Tof1/Csm3/Mrc1 acts to restrain the replicative MCM helicase when DNA synthesis is prohibited. Keeping the replication machinery intact allows restart of the replication fork when the block is relieved. Although the subunits of the Tof1/Csm3/Mrc1 complex are well studied, the impact of every single subunit on the triple complex formation and function needs to be established. This work studies the cellular localization and the chromatin binding of GFP-tagged subunits when the complex is intact and when a subunit is missing. We demonstrate that the complex is formed in cell nucleus, not the cytoplasm, as Tof1, Csm3 and Mrc1 enter the nucleus independently from one another. Via in situ chromatin binding assay we show that a Tof1-Csm3 dimer formation and chromatin binding is required to ensure the attachment of Mrc1 to chromatin. Our study indicates that the translocation into the nucleus is not the process to regulate the timing of chromatin association of Mrc1. We also studied the nuclear behavior of Mrc1 subunit in the process of adaptation to the presence hydroxyurea. Our results indicate that after prolonged HU incubation, cells bypass the S-phase checkpoint and proceed throughout the cell cycle. This process is accompanied by Mrc1 chromatin detachment and Rad53 dephosphorylation. In S. cerevisiae the subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3 independently enter the cell nucleus, where a Tof1-Csm3 dimer is formed to ensure the chromatin binding of Mrc1 and favor DNA replication and S-phase checkpoint fork arrest. In the process of adaptation to the presence of hydroxyurea Mrc1 is detached from chromatin and Rad53 checkpoint activity is diminished in order to allow S-phase checkpoint escape and completion of the cell cycle.

Association of bacteriochlorophyll a with the CsmA protein in chlorosomes of the photosynthetic green filamentous bacterium Chloroflexus aurantiacus

DEFF Research Database (Denmark)

Sakuragi, Y; Frigaard, N-U; Shimada, K

1999-01-01

with molecular masses of 11 and 18 kDa (CsmN and CmsM), whereas the spectral properties of BChl a and BChl c were not changed. By the new hexanol-detergent (HD) treatment, most BChl c and all of the detected proteins except CsmA were removed from the chlorosomes without changing the BChl a spectral properties....... Subsequent proteinase K treatment of these HD-treated chlorosomes caused digestion of CsmA and a simultaneous decrease of the BChl a absorption band. Based on these results, we suggest that CsmA is associated with BChl a in the chlorosomes. This suggestion was supported by the measured stoichiometric ratio...... of BChl a to CsmA in isolated chlorosomes, which was estimated to be between 1.2 and 2.7 by amino acid analysis of the SDS-PAGE-resolved protein bands....

Les estimations du capital humain au Canada : approche fondee sur le revenu de la vie entiere

OpenAIRE

Gu, Wulong; Wong, Ambrose

2010-01-01

Dans le present document, nous produisons une estimation de l'investissement en capital humain fonde sur le marche et du stock de ce capital au Canada au cours de la periode s'etendant de 1970 a 2007 selon l'approche fondee sur le revenu de la vie entiere. Nous comparons cette estimation a celle de l'investissement en capital physique et naturel et du stock de ce capital. En suivant la methode elaboree par Jorgenson et Fraumeni, nous estimons le stock de capital humain sous forme du revenu de...

Design Characteristics of Soft Control for APR+

Energy Technology Data Exchange (ETDEWEB)

Kim, Yongsoo; Sung, Chanho; Jung, Yeonsub [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

In the global nuclear industry, the design requirements have been largely divided into the US and the European ones. The APR+ design, based on the proven APR1400 design, was developed to fully comply with the US regulatory and utility requirements. It was also developed to improve the technical competitiveness and enlarge the export market share through design uniqueness and the improvement of safety. The robust design of safety and its validation were requested Post-Fukushima accident. So MMIS design and validation for reinforcing safety were accomplished in APR+ development project. In this paper, the design characteristics of soft control for APR+ are presented to enhance the safety of MMIS design. In this paper, the major design characteristics of soft control for APR+ were introduced to increase the safety of MMIS design. In addition to the design characteristics of soft control described above, the following should be investigated closely for APR+ to get into the global nuclear industry.

Design Characteristics of Soft Control for APR+

International Nuclear Information System (INIS)

Kim, Yongsoo; Sung, Chanho; Jung, Yeonsub

2016-01-01

In the global nuclear industry, the design requirements have been largely divided into the US and the European ones. The APR+ design, based on the proven APR1400 design, was developed to fully comply with the US regulatory and utility requirements. It was also developed to improve the technical competitiveness and enlarge the export market share through design uniqueness and the improvement of safety. The robust design of safety and its validation were requested Post-Fukushima accident. So MMIS design and validation for reinforcing safety were accomplished in APR+ development project. In this paper, the design characteristics of soft control for APR+ are presented to enhance the safety of MMIS design. In this paper, the major design characteristics of soft control for APR+ were introduced to increase the safety of MMIS design. In addition to the design characteristics of soft control described above, the following should be investigated closely for APR+ to get into the global nuclear industry

L'Empowerment au coeur des bouleversements induits par les TIC dans la gestion des ressources humaines

OpenAIRE

Blavier, André

2012-01-01

Observer l’influence des TIC (Technologies de l’Information et de la Communication” sur les ressources humaines à la lumière du seul débat “pour ou contre les réseaux sociaux dans l’entreprise ou l’organisation ?” est une approche bien trop restrictive. Les défis relatifs à l’évolution des ressources humaines s’inscrivent dans une perspective plus large, celle d’un environnement numérique global. Comme l’a souligné le rapport “Digital Economy Rankings 2010” d’IBM en collaboration avec l’Econ...

Robots humains, avez-donc une réalité ?

OpenAIRE

Amblard , Maxime; Boumaza , Amine

2015-01-01

International audience; Plusieurs laboratoires dans le monde travaillent à la création de robots humanoïdes . La technologie ayant considérablement évolué, il apparaît réaliste d’imaginer un quotidien accompagné de tels systèmes, à l’image du robot Nao, dont on discute encore comment lui faire partager des émotions pour simuler un comportement humain. Mais finalement, les robots sont déjà partout et depuis longtemps, dans les usines, les jouets électroniques, nos ordinateurs, nos tablettes, l...

Development of Core Simulator (CoSi) for APR1400 And Analysis of LPPT Result using APR1400-CoSi

International Nuclear Information System (INIS)

Moon, Sang-Rae; Kim, Yong-Bae; Lee, Eun-Ki

2014-01-01

According to NRC guidelines, Low Power Physics Test (LPPT) is required to be performed in low temperature/low pressure (160 .deg. C/42.2 kg/cm 2 ) as well as NOT/NOP (291.3 .deg. C/158.2 kg/cm 2 ) because Shin-Kori Unit 3 is FOAK nuclear power plant. Low Power Physics Test (LPPT) is essential to verify the nuclear design and robustness of reactor safety. LPPT consists of initial criticality, Point of Adding Heat (POAH), All Rod Out (ARO) Boron Concentration, Isothermal Temperature Coefficient (ITC), Control Rod Worth measurements and so on. KHNP-CRI has developed the Core Simulator for APR1400 (APR1400-CoSi) in order to improve the ability performing the LPPT. Especially, APR1400-CoSi has enhanced capability to calculate the full Core neutronic parameters by revising RAST-K that is three dimensional real time core kinetic program. APR1400-CoSi has been developed for education-training of Low Power Physics Test(LPPT). Particularly, APR1400-CoSi has an enhanced capability to calculate the full core neutronic parameters by revising RAST-K which is a three dimensional real time core kinetics program. Low Power Physics Test (LPPT) was performed using APR1400-CoSi and the results showed very similar values with the predicted ones. In other words, the initial core model of Shin-Kori Unit 3 in APR1400-CoSi system has been verified to be appropriate enough. Also, it was confirmed that the test range of Low Power Physics Test (LPPT) reamains effective even though the largest incremental bank reactivity is inserted in core by analyzing the power change during the rod SWAP test

Development of Reactor Coolant Pump for APR1400

Energy Technology Data Exchange (ETDEWEB)

Bang, Sang-Youn; Chu, Sung-Min; Chang, Jin-Young [Doosan Heavy Industries and Construction, Changwon (Korea, Republic of)

2015-10-15

The development was focused on the performance requirements for APR1400 and to achieve the goals of the safety, reliability and adaptability for APR1400 system design. In addition, APR1400 RCP design was customized considering convenience of installation, operation and maintainability. This paper describes the details of the development process, improved design feature and type test results. Based on development of core technology of RCP, DOOSAN supplies the localized and improved APR1400 RCP to Shin-Hanul 1 and 2 Project. This would be good experience that the RCP core technology can break foreign monopoly in supplying the domestic nuclear industry. Also, there expect APR1400 RCP can be sustainable revenue models in nuclear industry. Moreover, development of RCP will be a catalyst to enhance design capacity for equipment and system of nuclear power plant as well as evaluation and verification skills of Korean nuclear industry.

Thermomechanical CSM analysis of a superheater tube in transient state

Science.gov (United States)

Taler, Dawid; Madejski, Paweł

2011-12-01

The paper presents a thermomechanical computational solid mechanics analysis (CSM) of a pipe "double omega", used in the steam superheaters in circulating fluidized bed (CFB) boilers. The complex cross-section shape of the "double omega" tubes requires more precise analysis in order to prevent from failure as a result of the excessive temperature and thermal stresses. The results have been obtained using the finite volume method for transient state of superheater. The calculation was carried out for the section of pipe made of low-alloy steel.

ITAAC Development for APR1400 NRC Design Certification

International Nuclear Information System (INIS)

Kim, Jin Kwon; Kim, Myoung Ki

2013-01-01

ITAAC (Inspections, Tests, Analyses and Acceptance Criteria) is essential document for Design Certification, which is certified by NRC and ruled as the Appendix of the 10 CFR Part 52. Approximately 870 ITAAC items were selected for APR1400 Design Certification to be submitted to NRC. In this paper, the code and standard related to ITAAC and process of ITACC development are discussed to seek the way to complete the best ITAAC to get the Design Certification of APR1400 from NRC through the lessons learned from other competitive applicants. For saving the time and manpower to complete ITAAC of APR1400 NRC DC and reduction of the RAIs (Request Additional Information) from NRC, we took advantage of the lessons learned from the competitive designs like US-APWR and AP1000 based on KNGR ITAAC. Finally new and different ITAAC from ITAAC of KNGR was developed for APR1400 DC from NRC. RG 1.206 and SRPs were applied first in Korea to the APR1400 DCD preparation. For testability and acceptability check, ITAAC V and V table was completed by the system designers. APR1400 DCD will be submitted by the end of September this year and we hope that NRC issues lees RAIs on ITAAC document

Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis.

Directory of Open Access Journals (Sweden)

Jennifer J Wanat

2008-09-01

Full Text Available Chromosome movements are a general feature of mid-prophase of meiosis. In budding yeast, meiotic chromosomes exhibit dynamic movements, led by nuclear envelope (NE-associated telomeres, throughout the zygotene and pachytene stages. Zygotene motion underlies the global tendency for colocalization of NE-associated chromosome ends in a "bouquet." In this study, we identify Csm4 as a new molecular participant in these processes and show that, unlike the two previously identified components, Ndj1 and Mps3, Csm4 is not required for meiosis-specific telomere/NE association. Instead, it acts to couple telomere/NE ensembles to a force generation mechanism. Mutants lacking Csm4 and/or Ndj1 display the following closely related phenotypes: (i elevated crossover (CO frequencies and decreased CO interference without abrogation of normal pathways; (ii delayed progression of recombination, and recombination-coupled chromosome morphogenesis, with resulting delays in the MI division; and (iii nondisjunction of homologs at the MI division for some reason other than absence of (the obligatory CO(s. The recombination effects are discussed in the context of a model where the underlying defect is chromosome movement, the absence of which results in persistence of inappropriate chromosome relationships that, in turn, results in the observed mutant phenotypes.

Optimization Strategy of the APR+ BOP Technical Specifications

International Nuclear Information System (INIS)

Cho, Yoon Sang; Lee, Jae Gon; Han, Sung Heum

2016-01-01

The BOP is one of the key factors for successful project implementation of NPP. In constructing the APR1400 NPP, the BOP procurement has been one of the biggest concerns. Due to the design changes and increased capacity of equipment in NPP, lots of BOPs should be ‘first supplied equipment’ [hereinafter, ‘FSE’]. The manufacture-ability, and the performances of FSEs have not been fully proved and tested, manufacturers and suppliers are requested to submit Reports for Equipment Qualification Evaluation in accordance with 10 CFR 50.49, IEEE 323. They need at least 1-2 years’ tests for Environment Qualification (EQ) and Seismic Qualification (SQ). This study is focused how to prepare the BOP purchase specifications in order to control the FSEs, especially in safety class equipment. With the optimization plan for BOP packages of this study, the FSEs’ occurrence can be reasonably controlled as low as possible. For successful NPP project, the concerns in procuring BOPs shall be fully analyzed beforehand. Now Korea is preparing new era of APR+, with closing the time of APR1400. The technical specification of APR+ BOPs can be developed and prepared successfully and very effectively according to this optimization plan. This will be a great contribution not only in constructing APR+ in time, but also in exporting APR+ overseas, all over the world in the future

Optimization Strategy of the APR+ BOP Technical Specifications

Energy Technology Data Exchange (ETDEWEB)

Cho, Yoon Sang; Lee, Jae Gon; Han, Sung Heum [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

The BOP is one of the key factors for successful project implementation of NPP. In constructing the APR1400 NPP, the BOP procurement has been one of the biggest concerns. Due to the design changes and increased capacity of equipment in NPP, lots of BOPs should be ‘first supplied equipment’ [hereinafter, ‘FSE’]. The manufacture-ability, and the performances of FSEs have not been fully proved and tested, manufacturers and suppliers are requested to submit Reports for Equipment Qualification Evaluation in accordance with 10 CFR 50.49, IEEE 323. They need at least 1-2 years’ tests for Environment Qualification (EQ) and Seismic Qualification (SQ). This study is focused how to prepare the BOP purchase specifications in order to control the FSEs, especially in safety class equipment. With the optimization plan for BOP packages of this study, the FSEs’ occurrence can be reasonably controlled as low as possible. For successful NPP project, the concerns in procuring BOPs shall be fully analyzed beforehand. Now Korea is preparing new era of APR+, with closing the time of APR1400. The technical specification of APR+ BOPs can be developed and prepared successfully and very effectively according to this optimization plan. This will be a great contribution not only in constructing APR+ in time, but also in exporting APR+ overseas, all over the world in the future.

The APR1400 Core Design by Using APA Code System

International Nuclear Information System (INIS)

Choi, Yu Sun; Koh, Byung Marn

2008-01-01

The nuclear design for APR1400 has been performed to prepare the core model for Automatic Load Follow Operation Simulation. APA (ALPHA/ PHOENIXP/ ANC) code system is a tool for the multi-cycle depletion calculations for APR1400. Its detail versions for ALPHA, PHOENIX-P and ANC are 8.9.3, 8.6.1 and 8.10.5, respectively. The first and equilibrium core depletion calculations for APR1400 have been performed to assure the target cycle length and confirm the safety parameters. The parameters are satisfied within limitation about nuclear design criteria. This APR1400 core models will be based on the design parameters for APR1400 Simulator

L'évolution des valeurs de soin humain : une analyse dialectique de la proposition d'humanisation de Watson à la lumière d'une perspective nietzschéenne

OpenAIRE

Krol, Pawel

2014-01-01

La pratique du soin infirmier d’aujourd’hui hérite d’une longue et complexe évolution de valeurs. Outre les valeurs traditionnellement humaines de soigner, la pratique infirmière d’aujourd’hui intègre aussi des valeurs qui façonnent notre monde moderne. Ainsi, nous retraçons d’abord l’évolution de quelques-unes des valeurs traditionnelles rattachées au soin humain conservées dans les pratiques infirmières. Puis, nous montrons que certaines valeurs traditionnelles de soin humain sont progressi...

Limitations of BCC_CSM's ability to predict summer precipitation over East Asia and the Northwestern Pacific

KAUST Repository

Gong, Zhiqiang; Dogar, Muhammad Mubashar; Qiao, Shaobo; Hu, Po; Feng, Guolin

2017-01-01

This study examines the ability of the Beijing Climate Center Climate System Model (BCC_CSM) to predict the meridional pattern of summer precipitation over East Asia-Northwest Pacific (EA-NWP) and its East Asia-Pacific (EAP) teleconnection

Ce que nous faisons | Page 41 | CRDI - Centre de recherches pour ...

International Development Research Centre (IDRC) Digital Library (Canada)

aflatoxine du maïs et le degré d'exposition pour les humains au Zimbabwe. Ce projet examine des solutions d'après-récolte novatrices pour éviter la contamination du grain par l'aflatoxine. Zimbabwe. PROJECT ...

Antenna Pattern Range (APR)

Data.gov (United States)

Federal Laboratory Consortium — TheAntenna Pattern Range (APR)features a non-metallic arch with a trolley to move the transmit antenna from the horizon to zenith. At the center of the ground plane,...

Diagnostic Strategy in APR1400

International Nuclear Information System (INIS)

Kim, Dongyoung; Kim, Jonghyun

2013-01-01

These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room

Hard rock excavation at the CSM/OCRD test site using Swedish blast design techniques

International Nuclear Information System (INIS)

Holmberg, R.

1983-09-01

This report is the third in a series describing research conducted by the Colorado School of Mines for the Office of Crystalline Repository Development (OCRD) to determine the extent of blast damage in rock surrounding an underground opening. A special room, called the CSM/OCRD room, was excavated at the CSM experimental mine for the purpose of assessing blast damage in the rock around the room. Even though this mine is not proposed as a nuclear waste repository site, the instrumentation and methods of blast damage assessment developed in this project are applicable to proposed repository sites. This report describes the application of Swedish blasting technology for the excavation of the test room. The design of the blasting patterns including the selection of explosives, hole sizes and location, explosive loading densities, and delay intervals is based upon the theories of Langefors and Kihlstrom in combination with methods used at the Swedish Detonic Research Foundation for minimizing unwanted rock damage. The practical application of the design procedures to seven rounds and the achieved results is discussed

Ouverture commerciale : condition de la contribution effective du capital humain à la croissance économique des pays en développement

OpenAIRE

Yves Abessolo

2005-01-01

Dans la littérature actuelle une controverse persiste quant à la validation sur données de panel de l'hypothèse selon laquelle le capital humain contribue à la croissance. Nous confirmons ce résultat à l'aide d'un échantillon comprenant 23 pays d'Afrique subsaharienne entre 1980 et 1997. Cependant, l'estimation sur ces mêmes données de panel de modèles à termes interactifs puis à coefficients variables suggère que la contribution du capital humain à la croissance dépend du taux d'ouverture co...

Nigerian CSM project ready to roll.

Science.gov (United States)

1985-01-01

Nigeria's contraceptive social marketing (CSM) project is ready to be launched. Population Services Intenational (PSI) had completed the groundwork for the project, funded primarily by a $200,000 grant from the nonpofit D.K. Tyagi Fund. The Population Crisis Committee also provided support for the new project. At presstime, PSI was negotiating for continued project funding from the US Agency for International Development (USAID) and The Futures Group. PSI already has identified suitable products, researched brand names, arranged for distribution, appointed an advertising agency, designed packaging, written a marketing plan, and taken steps to create a local, nonprofit marketing organization to manage the project. PSI has named Tim Barton as the resident manager. He will take up his post once the issue of future funding is resolved. Contraceptives now available are distributed through the private sector and by the Planned Parenthood Federation of Nigeria, the Local International Planned Parenthood Federation affiliate. Nigeria's annual rate of population growth is about 3% and the country is urbanizing rapidly. A 1983 fertility report revealed that only 14% of Nigerian women had ever used any type of contraception; 6% of married women were using a contraceptive method at the time of the survey.

Egypt site of first CSM marketing audit.

Science.gov (United States)

1982-01-01

The 1st application of the marketing audit concept to a CSM project was implemented in Egypt's Family of the Future (FOF) contraceptive social marketing program in 1982. The audit defined the basic mission of the FOF as one of assisting the government in achieving its long range family planning goals. The stated FOF objectives are as follows: to create an awareness or an increase in demand for family planning services, particularly among the lower socioeconomic strata in urban Egypt; to establish and maintain a reliable supply mechanism to make FOF products more readily acceptable and available from pharmacies; and to consolidate the CSM operations and services first in the greater Cairo area and then expand to other urban areas in Egypt. The core strategy of the FOF incorporates several elements, including intensive media based advertising and personal promotion to promote the concept of family planning and to educate the general public about contraceptive alternatives. FOF product prices are considerably lower than commercial prices. Dr. Alan R. Andreasen, who conducted the audit on behalf of the FOF technical assistance contractor, noted that the FOF is growing rapidly and stated that the audit recommendations were intended to help FOF management. Dr. Andreasen conducted interviews with all the senior personnel at FOF and met with various specialized staff members such as the Public Relations Manager. Dr. Andreasen noted that at the time of the audit the FOF could claim major accomplishments in creating an awareness of the need for family planning and in product sales. From the time products were launched in 1979 through 1981 condom sales increased 260%. Foaming tablet sales increased more than 320% and IUD sales increased nearly 330%. The introduction of the Copper 7 IUD accounted for 35% of the growth of IUD sales in 1981. Couple years of protection (CYP) provided by all products increased from 45,533 in 1979 to 190,831 in 1981, an increase over 300%. The

Diagnostic Strategy in APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, Dongyoung; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2013-05-15

These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room.

Beyond Propietorship: Murphree's Laws on Community-based ...

International Development Research Centre (IDRC) Digital Library (Canada)

aflatoxine du maïs et le degré d'exposition pour les humains au Zimbabwe. Ce projet examine des solutions d'après-récolte novatrices pour éviter la contamination du grain par l'aflatoxine. Voir davantageTechnologies de gestion ...

JournalBase. Comparer les bases de données scientifiques internationales en sciences humaines et sociales (SHS

Directory of Open Access Journals (Sweden)

Denise Pumain

2010-01-01

Full Text Available Cet article dresse un tableau comparatif des contenus des bases de données et des listes de référence qui recensent les revues en sciences humaines et sociales (SHS. Il s’appuie sur JournalBase publié le 25 juin 2009 dans Cybergeo. Cette étude porte sur les bases AHCI et SSCI du Web of Science (publié par Thomson Reuters, de Scopus (publié par Elsevier, du European Reference Index for Humanities (ERIH (publié par la Fondation européenne pour la Science et de l’AERES (Agence pour l’évaluation de la recherche en France. La recherche a été réalisée en 2008 avec le soutien financier du TGE Adonis du CNRS. Avec quelque 20 000 entrées correspondant à environ 10 000 journaux différents, c’est une vue quasi exhaustive de la richesse des publications en sciences humaines et sociales qui est apportée par ce tableau. La nomenclature adoptée pour classer les revues par discipline est celle en 27 postes de la Fondation Européenne pour la Science. Les affectations multiples révèlent la multidisciplinarité des revues, assez fréquente en SHS, mais parfois aussi les incohérences des bases de données qui n’ont pas été rectifiées.L’article présente l’historique du projet, la méthodologie mise en place par les auteurs, les difficultés rencontrées dans la comparaison des données. Les premiers résultats mettent en évidence une couverture plus large de la liste ERIH pour les sciences humaines et une surreprésentation des revues anglophones dans les bases de données commerciales pour l’ensemble des disciplines. L’objectif de ce travail est d’alerter sur les contenus de ces bases de données, au moment où les outils bibliométriques soulèvent maints débats quant à leur application dans le champ des sciences humaines et sociales.

Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA.

Science.gov (United States)

Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

2014-07-01

Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant pathogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantly less virulent on both tomato and Arabidopsis thaliana. Moreover, infiltration of A. thaliana Col-0 leaves with DC3000 ΔaprA evoked a significantly higher level of expression of the defense-related genes FRK1 and PR-1 than did wild-type DC3000. In the flagellin receptor mutant fls2, pathogen virulence and defense-related gene activation did not differ between DC3000 and DC3000 ΔaprA. Together, these results suggest that AprA of DC3000 is important for evasion of recognition by the FLS2 receptor, allowing wild-type DC3000 to be more virulent on its host plant than AprA-deficient DC3000 ΔaprA. To provide further evidence for the role of DC3000 AprA in host immune evasion, we overexpressed the AprA inhibitory peptide AprI of DC3000 in A. thaliana to counteract the immune evasive capacity of DC3000 AprA. Ectopic expression of aprI in A. thaliana resulted in an enhanced level of resistance against wild-type DC3000, while the already elevated level of resistance against DC3000 ΔaprA remained unchanged. Together, these results indicate that evasion of host immunity by the alkaline protease AprA is important for full virulence of strain DC3000 and likely acts by preventing flagellin monomers from being recognized by its cognate immune receptor.

Development of Reference Source Terms for EU-APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, ByungIl; Lee, Chonghui; Lee, Dongsu; Ko, Heejin; Kang, Sangho [KEPCO Engineering and Construction Co. Inc., Yongin (Korea, Republic of)

2014-05-15

These source terms are developed for the typical U. S. NPP and do not reflect the design characteristics of EU-APR1400 (1,400 MWe PWR) which will be applied for the EUR certification in European countries. The process of developing the RST for EU-APR1400 is to undergo a similar process that NUREG-1465 had gone through when it came out with its proposed source terms. The purpose of this study is to develop the EU-APR1400 design-specific RST complied with the EUR. The Large LOCA is the reference equence used in the NUREG-1465 evaluation, whereas the EUAPR1400 risk-significant sequences are dominated by small LOCA and non-LOCA sequences. Moreover, when considering the EU-APR1400 has many design features to mitigate the consequences of severe accident phenomena, it is not surprising that the aspects of both release fractions and durations are distinctly different from NUREG-1465. This RST will be continuously updated to reflect to the design features of EU-APR1400, and then, be used as the reference for design purposes such as criteria satisfaction of radioactivity releases, equipment survivability, control room habitability for severe accident, and so on.

EU-APR Design in compliance with EUR Grid Requirement

Energy Technology Data Exchange (ETDEWEB)

Kim, Dong-Hwan; Lee, Keun-Sung [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

European Utility Requirements (EUR) provides technical requirements for the generation III nuclear power plant in the European countries. EUR grid requirements present the plant requirements to satisfy the needs of the grid network. The grid requirements are the precondition for the operation of a generating plant on the network. This paper describes EU-APR design which has taken account of EUR grid requirements. In this paper, EU-APR designs according to the EUR grid requirements were described. EU-APR was designed in compliance with the voltage and frequency operation field and also designed to have the capability of load following such as primary control, secondary control, and daily load following. Consequently, the EU-APR design according to the EUR grid requirements is expected to get competitiveness and enhance the license feasibility in the European nuclear market.

ÉTUDE DE CAS — Cuba : Le logement et le capital humain à Cuba ...

International Development Research Centre (IDRC) Digital Library (Canada)

10 janv. 2011 ... ÉTUDE DE CAS — Cuba : Le logement et le capital humain à Cuba ... Centre de recherches pour le développement international (CRDI) du Canada révèle ... Les ressources déjà limitées sont devenues encore plus rares. ... de l'Institut national pour l'hygiène, l'épidémiologie et la microbiologie (INHEM), ...

A Probability Analysis of the Generating Cost for APR1000+

Energy Technology Data Exchange (ETDEWEB)

Ha, Gag-Hyeon; Kim, Dae-Hun [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

The nuclear power plant market is expected to grow rapidly in order to address issues of global warming, cutting CO{sub 2} emissions and securing stable electricity supplies. Under these circumstances, the main primary goal of the APR1000+ development is to ensure export competitiveness in the developing countries in the Middle East and Southeast Asia. To that end, APR1000+(1,000MWe, 3.5 generation) will be developed based on APR+ (1,500MWe, 3.5 generation). And comparing to OPR1000(Korean Standard Nuclear power Plant, 2.5 generation), APR1000+ have many design features such as the 60 year design life time, comprehensive site requirement of 0.3g seismic design, stability improvement, operability improvement and provisions for severe accidents. In this simulation, the results of generating cost for APR1000+ preliminary conceptual design using a probability method was shown to be 48.37 ~ 74.22 won/kWh(median value 56.51 won/kWh). Those of OPR1000 was 42.08 ~ 61.77 won/kWh(median value 48.63 won/kWh). APR1000+ has -16.2% cost advantage over OPR1000 nuclear power plant. The main reason of this results is due to adding several safety designs.

The trauma registry compared to All Patient Refined Diagnosis Groups (APR-DRG).

Science.gov (United States)

Hackworth, Jodi; Askegard-Giesmann, Johanna; Rouse, Thomas; Benneyworth, Brian

2017-05-01

Literature has shown there are significant differences between administrative databases and clinical registry data. Our objective was to compare the identification of trauma patients using All Patient Refined Diagnosis Related Groups (APR-DRG) as compared to the Trauma Registry and estimate the effects of those discrepancies on utilization. Admitted pediatric patients from 1/2012-12/2013 were abstracted from the trauma registry. The patients were linked to corresponding administrative data using the Pediatric Health Information System database at a single children's hospital. APR-DRGs referencing trauma were used to identify trauma patients. We compared variables related to utilization and diagnosis to determine the level of agreement between the two datasets. There were 1942 trauma registry patients and 980 administrative records identified with trauma-specific APR-DRG during the study period. Forty-two percent (816/1942) of registry records had an associated trauma-specific APR-DRG; 69% of registry patients requiring ICU care had trauma APR-DRGs; 73% of registry patients with head injuries had trauma APR-DRGs. Only 21% of registry patients requiring surgical management had associated trauma APR-DRGs, and 12.5% of simple fractures had associated trauma APR-DRGs. APR-DRGs appeared to only capture a fraction of the entire trauma population and it tends to be the more severely ill patients. As a result, the administrative data was not able to accurately answer hospital or operating room utilization as well as specific information on diagnosis categories regarding trauma patients. APR-DRG administrative data should not be used as the only data source for evaluating the needs of a trauma program. Copyright © 2016 Elsevier Ltd. All rights reserved.

Le facteur humain et la sûreté de fonctionnement dans le ...

African Journals Online (AJOL)

Notre contribution porte sur le rôle fondamental du facteur humain dans le management intégré des risques d'une part et du rôle déterminant qu'il peut avoir à jouer pour que la sûreté de fonctionnement réponde à sa propriété d'autre part. Un rôle illustré à travers une analyse de risque dans un complexe de Gaz Naturel ...

Radiation exposure reduction in APR1400

International Nuclear Information System (INIS)

Bae, C. J.; Hwang, H. R.; Matteson, D. M.

2002-01-01

The primary contributors to the total occupational radiation exposure in operating nuclear power plants are operation and maintenance activities during refueling outages. The Advanced Power Reactor 1400 (APR1400) includes a number of design improvements and plans to utilize advanced maintenance methods and robotics to minimize the annual collective dose. The major radiation exposure reduction features implemented in APR1400 are a permanent refueling pool seal, quick opening transfer tube blind flange, improved hydrogen peroxide injection at shutdown, improved permanent steam generator work platforms, and more effective temporary shielding. The estimated average annual occupational radiation exposure for APR1400 based on the reference plant experience and an engineering judgment is determined to be in the order of 0.4 man-Sv, which is well within the design goal of 1 man-Sv. The basis of this average annual occupational radiation exposure estimation is an eighteen (18) month fuel cycle with maintenance performed to steam generators and reactor coolant pumps during refueling outage. The outage duration is assumed to be 28 days. The outage work is to be performed on a 24 hour per day basis, seven (7) days a week with overlapping twelve (12) hour work shifts. The occupational radiation exposure for APR1400 is also determined by an alternate method which consists of estimating radiation exposures expected for the major activities during the refueling outage. The major outage activities that cause the majority of the total radiation exposure during refueling outage such as fuel handling, reactor coolant pump maintenance, steam generator inspection and maintenance, reactor vessel head area maintenance, decontamination, and ICI and instrumentation maintenance activities are evaluated at a task level. The calculated value using this method is in close agreement with the value of 0.4 man-Sv, that has been determined based on the experience and engineering judgement

L’intégration du capital humain dans un outil de pilotage de la performance : le cas du tableau de bord stratégique

OpenAIRE

Borchani, Manel; Cheffi, Walid

2005-01-01

Cette communication examine comment un outil de contrôle de gestion, le tableau de bord stratégique (TdB), permet-il d’intégrer le capital humain dans le pilotage de la performance globale de l’entreprise ? La théorie des ressources (resource based view theory) considère que les Ressources Humaines (RH) sont des ressources internes précieuses pour l’entreprise. Cette théorie établit un lien entre elles, les compétences distinctives et l’avantage concurrentiel durable de l’entreprise. Un tel a...

APR1400 Locked Rotor Transient Analysis using KNAP

International Nuclear Information System (INIS)

Lee, Dong-Hyuk; Kim, Yo-Han; Ha, Sang Jun

2007-01-01

KEPRI (Korea Electric Power Research Institute) has developed safety analysis methodology for non-LOCA (Loss Of Coolant Accident) analysis of OPR1000 (Optimized Power Reactor 1000, formerly KSNP). The new methodology, named KNAP (Korea Non-LOCA Analysis Package), uses RETRAN as the main system analysis code for most transients. For locked rotor transient DNBR analysis, UNICORN-TM code is used. UNICORN-TM is the unified code of RETRAN, MASTER and TORC. The UNICORN-TM has 1-D and 3-D neutron kinetics calculation capability. For locked rotor DNBR analysis, 1-D neutron kinetics is used. In this paper, we apply KNAP methodology to APR1400 (Advanced Power Reactor 1400) locked rotor analysis and compare the results with those in the APR1400 SSAR(Standard Safety Analysis Report). The locked rotor transient is one of the 'decrease in reactor coolant system flow rate' events and the results are typically described in the chapter 15.3.3 of SAR (Safety Analysis Report). In this study, to confirm the applicability of the KNAP methodology and code system to APR1400, locked rotor transient is analyzed using UNICORN-TM code and the results are compared with those from APR1400 SSAR

APR1400 Locked Rotor Transient Analysis using KNAP

Energy Technology Data Exchange (ETDEWEB)

Lee, Dong-Hyuk; Kim, Yo-Han; Ha, Sang Jun [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

2007-07-01

KEPRI (Korea Electric Power Research Institute) has developed safety analysis methodology for non-LOCA (Loss Of Coolant Accident) analysis of OPR1000 (Optimized Power Reactor 1000, formerly KSNP). The new methodology, named KNAP (Korea Non-LOCA Analysis Package), uses RETRAN as the main system analysis code for most transients. For locked rotor transient DNBR analysis, UNICORN-TM code is used. UNICORN-TM is the unified code of RETRAN, MASTER and TORC. The UNICORN-TM has 1-D and 3-D neutron kinetics calculation capability. For locked rotor DNBR analysis, 1-D neutron kinetics is used. In this paper, we apply KNAP methodology to APR1400 (Advanced Power Reactor 1400) locked rotor analysis and compare the results with those in the APR1400 SSAR(Standard Safety Analysis Report). The locked rotor transient is one of the 'decrease in reactor coolant system flow rate' events and the results are typically described in the chapter 15.3.3 of SAR (Safety Analysis Report). In this study, to confirm the applicability of the KNAP methodology and code system to APR1400, locked rotor transient is analyzed using UNICORN-TM code and the results are compared with those from APR1400 SSAR.

Design characteristics of EU-APR1400 on-site power system

International Nuclear Information System (INIS)

Kim, D.H.; Kim, Y.S.; Kim, Y.S.

2014-01-01

In the global nuclear market, US and European design requirements have been largely used to develop the design of nuclear power plants(NPPs). The APR1400 design was developed on the basis of US regulatory guide and EPRI utility requirements document(URD). In order to enlarge the export market of APR1400, KHNP (Korea Hydro & Nuclear Power Co., Ltd) has developed the EU-APR1400 design which complies with the European nuclear design requirements. In this paper, the design characteristics of EU-APR1400 on-site power system developed according to the European design requirements of electrical power system are described. The European main design requirements of electrical power system involve 50 Hz rated frequency, 400/110 kV grid voltage, the application of the diversity and the redundancy, and so on. The EU-APR1400 on-site power system has been developed on the basis of these requirements. The representative designs include the redundancy, diversity, independence design, the emergency power supply design, the design for providing electrical power to the dedicated severe accident systems, and the design for European grid requirements. (author)

Pour une ingénierie des Environnements Informatiques pour l'Apprentissage Humain

OpenAIRE

Tchounikine , Pierre

2002-01-01

Nous proposons dans cet article une réflexion sur la notion d'ingénierie des EIAH (Environnements Informatiques pour l'Apprentissage Humain). Nous posons tout d'abord une définition de l'ingénierie des EIAH : travaux visant à définir des éléments de méthodes et de techniques reproductibles et/ou réutilisables facilitant la mise en place (conception – réalisation – expérimentation – évaluation - diffusion) d'environnements de formation ou d'apprentissage (dans leur articulation avec les dispos...

Assessment and correction of BCC_CSM's performance in capturing leading modes of summer precipitation over North Asia

KAUST Repository

Gong, Zhiqiang; Dogar, Muhammad Mubashar; Qiao, Shaobo; Hu, Po; Feng, Guolin

2017-01-01

in the tropical East Pacific. Nevertheless, BCC_CSM exhibits limited prediction skill over most part of NA and presents a deficiency in reproducing the EOF1's and EOF2's spatial pattern over central NA and EOF2's interannual variability. This can be attributed

ÉTUDE DE CAS — Cuba : Le logement et le capital humain à Cuba ...

International Development Research Centre (IDRC) Digital Library (Canada)

10 janv. 2011 ... Colin Campbell. Des projets communautaires améliorent la santé du cœur de La Havane. La vie en plein centre-ville peut mettre à rude épreuve la résistance des gens. Lorsque les quartiers périclitent, le dépérissement de la santé humaine suit de près. Un projet mené à Cuba avec l'appui du Centre de ...

Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

OpenAIRE

Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M.F; Van der Ent, S.; Van Strijp, J.A.G.

2014-01-01

Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of bacterial species. In addition, we investigated the role of AprA in virulence of the bacterial plant athogen P. syringae pv. tomato DC3000. The AprA-deficient DC3000 ΔaprA knockout mutant was significantl...

APR1400 CEA Withdrawal at Power Accident Analysis using KNAP

International Nuclear Information System (INIS)

Lee, Dong-Hyuk; Yang, Chang-Keun; Kim, Yo-Han; Sung, Chang-Kyung

2006-01-01

KEPRI (Korea Electric Power Research Institute) has been developing safety analysis methodology for non- LOCA (Loss Of Coolant Accident) analysis of OPR1000 (Optimized Power Reactor 1000, formerly KSNP). The new methodology, named KNAP (Korea Non-LOCA Analysis Package), uses RETRAN as the main system analysis code. RETRAN code is a non- LOCA safety analysis code developed by EPRI. The new methodology will replace existing CE (Combustion Engineering) supplied codes and methodologies currently used in non-LOCA analysis of OPR1000. In this paper, we apply KNAP methodology to APR1400 (Advanced Power Reactor 1400). The CEA (Control Element Assembly) withdrawal at power accident is one of the 'reactivity and power distribution anomalies' events and the results are typically described in the chapter 15.4.2 of SAR (Safety Analysis Report). The APR1400 has been designed to generate 1,400MWe of electricity with advanced features for greatly enhanced safety and economic goals. The CEA withdrawal at power analysis in APR1400 SSAR (Standard Safety Analysis Report) is analyzed with CESEC-III computer code. In this study, to confirm the applicability of the KNAP methodology and code system to APR1400, CEA withdrawal at power accident is analyzed using RETRAN code and it is compared with results from APR1400 SSAR

System Response Analysis of LOCV for APR1400 Using KNAP

International Nuclear Information System (INIS)

Kim, Yo-Han; Sung, Chang-Kyung; Jun, Hwang-Yong

2006-01-01

Korea Electric Power Research Institute (KEPRI) of Korea Electric Power Corporation (KEPCO) has been developed the non-loss-of-coolant accident (non-LOCA) analysis methodology, called as the Korea Non-LOCA Analysis Package (KNAP), for the typical Optimized Power Reactor 1000 (OPR1000) plants. Considering current licensing methodology conducted by ABB-CE, however, the KNAP could be applied to Advanced Power Reactor 1400 (APR1400). In spite of some difference in components of two plant types, there is a close resemblance between their nuclear steam supply systems (NSSS). So, in this study, the loss of condenser vacuum (LOCV) event were analyzed using KNAP for APR1400 to estimate the feasibility of the application and the results were compared with those given in APR1400 Standard Safety Analysis Report (SSAR), which were calculated using the CESEC-III code of ABB-CE. Through the study, it was concluded that the KNAP could be applicable to APR1400 on the view point of LOCV event

Functional Requirement Analysis and Function Allocation for APR 1400

International Nuclear Information System (INIS)

Nuraslinda, Anuar; Florah, Kamanja; Noloyiso, Mtoko and others

2013-01-01

This paper intends to fulfill the FRA and FA of the HFE as required in Chapter 4 of NUREG-0711 rev. 3 for APR1400 to satisfy both plant safety and power generation objectives. This paper aims to evaluate the FRA and FA for APR1400. The allocation of function is done at the system level for all processes for both the power generation and safety goals, following the NUREG/CR-3331 guideline. As a conclusion, this paper has successfully implemented the requirements and methodology specified in NUREG-0711 for APR 1400. The Functional Requirement Analysis (FRA) and Function Allocation (FA) are required by the regulation in the Human Factors Engineering (HFE) program. The FRA defines the functions, processes, and system for plant safety and power generation. The FA allocates the functions to human operator, automation, or a combination of two. The FRA and FA for APR1400 have been performed in the very early stage of development but only for the plant safety. However, the analysis did not include the goal of power generation and also did not fully satisfy the latest revision of NUREG-0711

Hybridation de la ressource humaine dans les associations : déterminants et effets.

OpenAIRE

Gontier , Patricia; Dansac , Christophe; Vachée , Cécile

2014-01-01

International audience; À l’image de la multiplicité des rôles que peuvent tenir les associations et autres organisations non orientées vers le profit dans nos sociétés, les ressources humaines impliquées dans les associations ou autres organisations non orientées vers le profit sont multiples. Dans leurs motivations, leurs compétences, et leurs parcours, les individus qui contribuent à ces organisations sont très différents. Parmi les bénévoles, on peut ainsi dissocier ceux qui administrent ...

Des relations plus humaines ?

Directory of Open Access Journals (Sweden)

Ferruccio Ricciardi

2012-05-01

Full Text Available À partir d’une approche sociohistorique, cet article s’intéresse aux effets de la croissance économique sur l’identité des cadres, en l’occurrence les groupements de cadres et patrons italiens qui, au lendemain de la Seconde Guerre mondiale, essaient de conjuguer les principes du catholicisme social dont ils se réclament dans l’arène publique avec les logiques issues du productivisme managérial américain qui s’impose en Europe occidentale. Le prisme des méthodes de « relations humaines » pour la gestion des salariés est ici utilisé pour rendre compte des modes de construction d’une identité professionnelle prise entre l’« esprit du religieux » et l’« esprit du capitalisme ». La déclinaison des « relations humaines » en fonction du projet de justice sociale préconisé par la doctrine sociale de l’Église en ressort amendée, car elles sont perçues moins comme un levier pour l’intégration des salariés que comme un instrument au service du contrôle politique de ceux-ci.Are the relations more human? Catholic executives and the employers facing the managerial productivism (Italy, ‘50s-‘60sThis article deals with the effects of economic growth on the identity of managers and the employers, especially the Italian ones who, after the World War II, try to combine their catholic principles with the issues of the managerial productivism spreading in the Western Europe. Adopting a socio-historical framework, the article analyses the implementation of the human relations techniques for the management of personnel in order to grasp a split professional identity between the ‘spirit of religious’ and the ‘spirit of capitalism’. The declination of the human relations theories according to the principles of social justice advocated by the social doctrine of the Church has been amended, because of the perception of the human relations as a means for political control of workers rather than an

Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl-peptidase IV.

Science.gov (United States)

Herlihy, Sarah E; Tang, Yu; Phillips, Jonathan E; Gomer, Richard H

2017-03-01

Autocrine proliferation repressor protein A (AprA) is a protein secreted by Dictyostelium discoideum cells. Although there is very little sequence similarity between AprA and any human protein, AprA has a predicted structural similarity to the human protein dipeptidyl peptidase IV (DPPIV). AprA is a chemorepellent for Dictyostelium cells, and DPPIV is a chemorepellent for neutrophils. This led us to investigate if AprA and DPPIV have additional functional similarities. We find that like AprA, DPPIV is a chemorepellent for, and inhibits the proliferation of, D. discoideum cells, and that AprA binds some DPPIV binding partners such as fibronectin. Conversely, rAprA has DPPIV-like protease activity. These results indicate a functional similarity between two eukaryotic chemorepellent proteins with very little sequence similarity, and emphasize the usefulness of using a predicted protein structure to search a protein structure database, in addition to searching for proteins with similar sequences. © 2016 The Protein Society.

Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl‐peptidase IV

Science.gov (United States)

Herlihy, Sarah E.; Tang, Yu; Phillips, Jonathan E.

2017-01-01

Abstract Autocrine proliferation repressor protein A (AprA) is a protein secreted by Dictyostelium discoideum cells. Although there is very little sequence similarity between AprA and any human protein, AprA has a predicted structural similarity to the human protein dipeptidyl peptidase IV (DPPIV). AprA is a chemorepellent for Dictyostelium cells, and DPPIV is a chemorepellent for neutrophils. This led us to investigate if AprA and DPPIV have additional functional similarities. We find that like AprA, DPPIV is a chemorepellent for, and inhibits the proliferation of, D. discoideum cells, and that AprA binds some DPPIV binding partners such as fibronectin. Conversely, rAprA has DPPIV‐like protease activity. These results indicate a functional similarity between two eukaryotic chemorepellent proteins with very little sequence similarity, and emphasize the usefulness of using a predicted protein structure to search a protein structure database, in addition to searching for proteins with similar sequences. PMID:28028841

A Probability Analysis of the Generating Cost for EU-APR1400 Single Unit

International Nuclear Information System (INIS)

Ha, Gak Hyeon; Kim, Sung Hwan

2014-01-01

The nuclear power plant market is expected to grow rapidly in order to address issues of global warming, reducing CO 2 emissions and securing stable electricity supplies. Under these circumstances, the main primary goal of the EU-APR100 development is to ensure export competitiveness in the European countries. To this end, EU-APR1400 have been developed based one te APR1400 (Advanced Power Reactor, GEN Type) The EU-APR1400 adds many advanced design features to its predecessor, as outlined below in Table 1. In this simulation, the results of the generating cost of the EU-APR1400 single unit were determined using the probability cost analysis technique, the generating cost range was shown to be 56.16 ∼ 70.92 won/kWh.

A Probability Analysis of the Generating Cost for EU-APR1400 Single Unit

Energy Technology Data Exchange (ETDEWEB)

Ha, Gak Hyeon; Kim, Sung Hwan [KHNP CRI, Seoul (Korea, Republic of)

2014-10-15

The nuclear power plant market is expected to grow rapidly in order to address issues of global warming, reducing CO{sub 2} emissions and securing stable electricity supplies. Under these circumstances, the main primary goal of the EU-APR100 development is to ensure export competitiveness in the European countries. To this end, EU-APR1400 have been developed based one te APR1400 (Advanced Power Reactor, GEN Type) The EU-APR1400 adds many advanced design features to its predecessor, as outlined below in Table 1. In this simulation, the results of the generating cost of the EU-APR1400 single unit were determined using the probability cost analysis technique, the generating cost range was shown to be 56.16 ∼ 70.92 won/kWh.

Thermo-Mechanical Characterisation of In-Plane Properties for CSM E-glass Epoxy Polymer Composite Materials – Part 1

DEFF Research Database (Denmark)

Jakobsen, Johnny; Jensen, Martin; Andreasen, Jens H.

2013-01-01

The in-plane thermo-mechanical properties and residual stresses of a CSM E-glass/Epoxy material are characterised through the use of DSC and TMA. The measured data is used to generate material models which describe the mechanical behaviour as a function of conversion and temperature. The in-plane...

APR1400 Fluidic Device Sensitivity Test

International Nuclear Information System (INIS)

Choi, Nam Hyun; Chu, In Cheol; Min, Kyong Ho; Song, Chul Hwa

2005-12-01

In the safety injection tank at the emergency core cooling system of APR1400, a new safety design feature, passive fluidic device is equipped which includes no active driving system. It is essential to evaluate the new design feature with various experiments. For this reason, three categories of sensitivity tests have been performed in the present study. As the first sensitivity experiment, the effect of the height of the stand pipe was investigated. The second sensitivity test was conducted with removing the insert plate gasket to examine its effect. The effect of the expansion of the control nozzle width was ascertained from the third sensitivity test. The results of each test showed that the passive fluidic device which will be equipped in the SIT tank of APR1400 has great integrity and repeatability

Le facteur humain. Réinventer notre rapport à la technologie de Vicente

Directory of Open Access Journals (Sweden)

Jacques Leplat

2005-11-01

Full Text Available Kim Vicente est connu du milieu ergonomique pour son très bon ouvrage « Cognitive work analysis » qui manifeste à la fois son expertise et son talent pédagogique. Ingénieur de formation, il a enseigné ensuite à l’université en tant que « professeur en ingénierie des facteurs humains ». Professeur invité au MIT et conseiller à la NASA, il est l’auteur de nombreuses publications de recherche qu’on rangerait dans l’ergonomie cognitive. Le présent ouvrage, qu’il a publié en anglais en 2003, est d...

Critical analyses on the localized corrosion behaviour in materials of energetic interests: Inconcel 600 CSM and Deltacogne

International Nuclear Information System (INIS)

Borello, A.; Frangini, S.; Masci, D.

1989-06-01

Concerning the two commonly observed phenomena of localized corrosion of Inconel 600 in high temperature caustic environments normally encountered in steam generators of PWR nuclear reactors, the aim of this work is to investigate the intergranular and the stress corrosion cracking behaviour of two heats of Alloy 600, having different origin. In fact one heat was produced by Centro Sviluppo Materiali (CSM) in laboratory scale; the other one was manufactured by Deltacogne following conventional industrial practices. The evaluation of intergranular corrosion susceptibility has been performed by means of the modified Huey test and the Electrochemical Potentiokinetic Reactivation (EPR). The stress corrosion cracking susceptibility was determined by the slow strain rate technique. The results of the present study show that the CSM heat has a better behaviour than the Deltacogne one as for the stress corrosion cracking susceptibility. On the contrary, concerning the intergranular corrosion resistance, both used tests point out that the Deltacogne material has a lower susceptibility to this type of localized corrosion. The sensitization areas in the TTS diagram, depend, even for the same heat, on the type of the test used for the evaluation. (author)

Evaluation of the Planned Outage Durations in EU-APR

Energy Technology Data Exchange (ETDEWEB)

Jung, Byung Joon; Lee, Keun Sung [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

EU-APR has been designed to comply with European Utility Requirements (EUR) and nuclear design requirements of the European countries. And it is modified and improved from its original design of APR1400. The whole duration varies depending on items for additional process. Refueling and regular maintenance outage is comprised of basic processes and Main turbine-generator outage includes dismantling inspection of main generator and high pressure turbine as a critical path in addition to basic processes. In-Service Inspection Outage includes Automatic ultrasonic inspection on the upper side/lower side of a nuclear reactor as a critical path in addition to basic processes. The planned outage durations of EU-APR are optimized according to the above results. And they are complied with EUR Requirement (EUR 2.2.7.2.2 B), respectively. In addition, outage duration can be reduced with improved operating technology and more maintenance friendly environment including betterment of filling, drain and ventilation.

Evaluation of the Planned Outage Durations in EU-APR

International Nuclear Information System (INIS)

Jung, Byung Joon; Lee, Keun Sung

2016-01-01

EU-APR has been designed to comply with European Utility Requirements (EUR) and nuclear design requirements of the European countries. And it is modified and improved from its original design of APR1400. The whole duration varies depending on items for additional process. Refueling and regular maintenance outage is comprised of basic processes and Main turbine-generator outage includes dismantling inspection of main generator and high pressure turbine as a critical path in addition to basic processes. In-Service Inspection Outage includes Automatic ultrasonic inspection on the upper side/lower side of a nuclear reactor as a critical path in addition to basic processes. The planned outage durations of EU-APR are optimized according to the above results. And they are complied with EUR Requirement (EUR 2.2.7.2.2 B), respectively. In addition, outage duration can be reduced with improved operating technology and more maintenance friendly environment including betterment of filling, drain and ventilation

Current status of integrated HFE V and V system of APR1400

International Nuclear Information System (INIS)

Lee, M. S.; Hong, J. H.; Lee, S. H.; Lee, Y. K.

2006-01-01

The first Advanced Light Water Reactor called Advanced Power Reactor (APR1400) has many specific features such as passive safety features, digital I and C, and digitalized main control room design. This digital-based neo-concept main control room design needs comprehensive verification and validation process to get the license for construction. An integrated system for APR1400 MMIS design validation is under development by KEPRI with the participating of KHNP. The facility which is based on the NUREG/CR-6393 and ANS3.5 can simulate all of the dynamic functions and responses of APR1400, and measure the human factors by using conventional subject methods and measuring the operator's biological signals. This system will be used in human factors V and V process of the PRM (NUREG0711) of APR1400 MMIS design. (authors)

Study on Maintenance Personnel Development Plan For The Exported APR1400 Commissioning

International Nuclear Information System (INIS)

Cho, Sungbae; Kim, Jongdae; Jun, Hokwang; Hwang, Inok; Kang, Jaeyuel

2012-01-01

This paper indicates ways to develop maintenance personnel for the exported APR1400 commissioning. The exported APR1400 has not been experienced ay maintenance yet, and requirements for maintenance personnel have not been clarified yet. Based on sound maintenance experience, KEPCO Plant Service and Engineering Company (KEPCO KPS) has studied on maintenance training and career requirement to establish a development plan of the maintenance personnel for the exported nuclear power plant. By defining manpower and training requirement, and mobilization plan, we expect to secure reliability of the exported APR1400

Contribution à la théorie du capital humain : Les bénéfices à court ...

African Journals Online (AJOL)

Les enfants scolarisés communiquent-ils à leurs parents paysans des connaissances reçues de l'école ? C'est la problématique de notre étude qui se fixe pour objectif de revisiter la théorie classique du capital humain, plus singulièrement dans le registre du délai des bénéfices que l'on en tire (court ou long terme).

L'écosanté, pour améliorer la santé humaine et préserver l ...

International Development Research Centre (IDRC) Digital Library (Canada)

27 oct. 2010 ... Puis, en 1992, il a lancé le programme Santé, société et environnement, qui réunissait des spécialistes de divers domaines dans le but d'étudier les répercussions des facteurs environnementaux sur la santé. La création du programme Écosystèmes et santé humaine (ÉCOSANTÉ) en 1996 a permis de ...

La prolongation de la vie humaine selon Francis Bacon. Ou : quel Tithon voulons-nous être ?

Directory of Open Access Journals (Sweden)

Dominique Weber

2011-07-01

Full Text Available Afin de comprendre avec exactitude la manière dont Francis Bacon envisage la question de la prolongation de la vie humaine, il faut impérativement examiner l’assise théologique de la réflexion du philosophe à ce sujet. Il convient aussi de restituer l’intégration de cette réflexion dans les objectifs plus amples de la philosophie naturelle nouvelle. Enfin, il est nécessaire de comprendre les dimensions proprement morales de la question. Car la prolongation de la vie humaine n’est pas seulement, au sein de la philosophie naturelle nouvelle, un cas parmi d’autres des recherches qu’il faut désormais effectuer : en réalité, c’est elle qui lui donne et qui lui fixe son sens ; avec elle se joue l’effectivité de l’identité espérée entre science et puissance. Mais il faut encore préciser qu’il ne s’agit aucunement pour l’homme de vieillir pour vieillir : il s’agit pour lui de pouvoir vieillir bien. Les leçons que Bacon tire de la fable de Tithon sont ici véritablement décisives.

48 CFR 1552.235-76 - Treatment of Confidential Business Information (APR 1996).

Science.gov (United States)

2010-10-01

... Business Information (APR 1996). 1552.235-76 Section 1552.235-76 Federal Acquisition Regulations System... Provisions and Clauses 1552.235-76 Treatment of Confidential Business Information (APR 1996). As prescribed in 1535.007-70(c), insert the following clause: Treatment of Confidential Business Information (TSCA...

Implementasi Automatic Packet Reporting System (APRS) Untuk Paket Data Pemantauan dan PengukuranUntuk Paket Data Pemantauan dan Pengukuran

OpenAIRE

Arief Goeritno

2016-01-01

Telah dilakukan implementasi Automatic Packet Reporting System (APRS) untuk paket data pemantauan dan pengukuran melalui tujuan penelitian, berupa: a) penyetelan program aplikasi pada jaringan APRS dan b) pengukuran terhadap penerimaan data berdasarkan kinerja sensor-sensor. Penyetelan program aplikasi APRS merupakan konfigurasi perangkat lunak untuk APRS yang akan digunakan pada stasiun penerimaan data APRS dengan program aplikasi yang biasa digunakan, yaitu hyperterminal dan UI-View 32. Pen...

In-situ load-deformation characterization of the CSM/OCRD jointed test block

International Nuclear Information System (INIS)

Richardson, A.M.; Hustrulid, W.; Brown, S.; Ubbes, W.

1985-01-01

An extensive ambient-temperature test series has recently been completed on a block of Precambrian Gneiss at the Colorado School of Mines (CSM) Experimental Mine in Idaho Springs, Colorado. Block tests came into existence out of a desire to test a relatively large volume of rock and thereby minimize the scaling problems encountered when laboratory test results are used to obtain modeling parameters for full-size structures. A typical block test involves isolation of a large, approximately two-meter cube of rock by cutting slots on four sides and inserting flatjacks for loading. Much interest has recently centered around block tests as a promising method for in-situ characterization of rock-masses for licensing future commercial nuclear-waste repositories in crystalline rock. To date only a few block tests have been conducted

48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

Science.gov (United States)

2010-10-01

... Control Act Confidential Business Information (APR 1996). 1552.235-75 Section 1552.235-75 Federal... Confidential Business Information (APR 1996). As prescribed in 1535.007(b), insert the following provision: Access to Toxic Substances Control Act Confidential Business Information (APR 1996) In order to perform...

Big Brother is watching but helping you : analyse et interprétation de mouvements humains (expressions, gestes, postures) : Big Brother is watching but helping you : human motion analysis and interpretation

OpenAIRE

Caplier , Alice

2005-01-01

Mes activités de recherche portent sur l'analyse et l'interprétation des mouvements humains à partir de données visuelles avec comme application principale l'amélioration du processus de communication entre l'homme et la machine. L'idée sous-jacente est de tendre vers une communication homme machine non pas par l'intermédiaire des traditionnels écran/clavier/souris mais vers un processus plus « humain » de communication. Ceci suppose que la machine est capable de reconnaître et d'interpréter ...

Selective Protein Extraction from Chlorobium tepidum Chlorosomes Using Detergents. Evidence That CsmA Forms Multimers and Binds Bacteriochlorophyll a

DEFF Research Database (Denmark)

Bryant, Donald A; Vassilieva, Elena V; Frigaard, Niels-Ulrik

2002-01-01

and location of this BChl a are not yet clearly understood. Chlorosomes were treated with sodium dodecyl sulfate (SDS), Lubrol PX, or Triton X-100, separately or in combination with 1-hexanol, and the extracted components were separated from the residual chlorosomes by ultrafiltration on centrifugal filters....... When chlorosomes were treated with low concentrations of SDS, all proteins except CsmA were extracted. However, this treatment did not significantly alter the size and shape of the chlorosomes, did not extract the BChl a, and caused only minor changes in the absorption spectrum of the chlorosomes....... Cross-linking studies with SDS-treated chlorosomes revealed the presence of multimers of the major chlorosome protein, CsmA, up to homooctamers. Extraction of chlorosomes with SDS and 1-hexanol solubilized all ten chlorosome envelope proteins as well as BChl a. Although the size and shape...

Capital humain et croissance : la littérature empirique à un tournant ?

OpenAIRE

Gurgand, Marc

2005-01-01

Depuis le début des années 1990, la littérature empirique sur le rôle du capital humain dans la croissance économique fourmille de résultats contradictoires. Cet article récapitule les éléments du débat en opposant les contributions selon deux axes, celui de la spécification économique et celui des méthodes économétriques. Le premier axe oppose les estimations qui s’appuient sur des modèles de convergence des économies, à proximité de leur équilibre stationnaire et celles, de nature plus comp...

Être humain, être dans la lune ?

Directory of Open Access Journals (Sweden)

Augustin Berque

2010-09-01

Full Text Available L’ouvrage commence par une épigraphe de Heidegger : […] ce sont les structures constituant l’existence qu’il s’agit de dégager l’une après l’autre. L’ensemble que forment ces structures réunies, nous l’appelons l’existentialité. Son analytique a le caractère d’une entente non pas existentielle mais existentiale . « […] nicht eines existenziellen, sondern existenzialen Verstehens » (Heidegger, [1927] 1993, p. 12. Il faut en effet savoir, ce que nous ...

Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity.

Science.gov (United States)

Lee, Seung Ah; Jang, Seong Han; Kim, Byung Hyun; Shibata, Toshio; Yoo, Jinwook; Jung, Yunjin; Kawabata, Shun-Ichiro; Lee, Bok Luel

2018-04-01

The biochemical characterization of virulence factors from entomopathogenic bacteria is important to understand entomopathogen-insect molecular interactions. Pseudomonas entomophila is a typical entomopathogenic bacterium that harbors virulence factors against several insects. However, the molecular actions of these factors against host innate immune responses are not clearly elucidated. In this study, we observed that bean bugs (Riptortus pedestris) that were injected with P. entomophila were highly susceptible to this bacterium. To determine how P. entomophila counteracts the host innate immunity to survive within the insect, we purified a highly enriched protein with potential host insect-killing activity from the culture supernatant of P. entomophila. Then, a 45-kDa protein was purified to homogeneity and identified as AprA which is an alkaline zinc metalloprotease of the genus Pseudomonas by liquid chromatography mass spectrometry (LC-MS). Purified AprA showed a pronounced killing effect against host insects and suppressed both host cellular and humoral innate immunity. Furthermore, to show that AprA is an important insecticidal protein of P. entomophila, we used an aprA-deficient P. entomophila mutant strain (ΔaprA). When ΔaprA mutant cells were injected to host insects, this mutant exhibited extremely attenuated virulence. In addition, the cytotoxicity against host hemocytes and the antimicrobial peptide-degrading ability of the ΔaprA mutant were greatly decreased. These findings suggest that AprA functions as an important insecticidal protein of P. entomophila via suppression of host cellular and humoral innate immune responses. Copyright © 2017 Elsevier Ltd. All rights reserved.

Radiological Impacts Assessment during Normal Decommissioning Operation for EU-APR

Energy Technology Data Exchange (ETDEWEB)

Hwang, Do Hyun; Lee, Keun Sung [KHNP CRI, Daejeon (Korea, Republic of); Lee, ChongHui [KEPCO Engineering and Construction, Gimcheon (Korea, Republic of)

2016-10-15

In this paper, radiological impacts on human beings during normal execution of the decommissioning operations from the current standard design of EU-APR which has been modified and improved from its original design of APR1400 to comply with EUR, are evaluated. Decommissioning is the final phase in the life cycle of a nuclear installation, covering all activities from shutdown and removal of fissile material to environmental restoration of the site. According to article 5.4 specified in chapter 2.20 of European Utility Requirements (EUR), all relevant radiological impacts on human being should be considered during the environmental assessment of decommissioning, including external exposure from direct radiation of plant and other radiation sources, and internal exposure due to inhalation and ingestion. In this paper, radiological impacts on human beings during normal circumstances of the decommissioning operation were evaluated from the current standard design of EU-APR based on the simple transport model and practical generic methodology for assessing the radiological impact provided by IAEA. The results of dose assessment fulfilled the dose limit for all scenarios.

GOTHIC Simulation of APR1400 Auxiliary Charging Pump room heat up

Energy Technology Data Exchange (ETDEWEB)

Ha, Hui-Un; Heo, Sun [KHNP, Daejeon (Korea, Republic of)

2014-10-15

As a part of the Advanced Power Reactor 1400 (APR1400) U. S. Nuclear Regulatory Commission Design Certification (NRC DC) project, we have been investigating Auxiliary Charging Pump (ACP) room heat up. With reference to the design specification of the ACP room, we determined input information and developed a GOTHIC model of the APR1400 ACP room. This calculation model is described herein, and representative results from the calculation are presented as well. The results of the present paper are used to determine the integrity of ACP operating in the accident. APR 1400 GOTHIC model was developed for ACP room heat up calculation. Calculation results confirm that door opening is cooling the room properly. It is found that the difference due to the surface option of heat conductors is insignificant. Based on this result, further studies should be performed to confirm integrity of ACP.

Conceptual Designs for the Performance Improvement of APR1400 SIT and Preliminary Performance Evaluation

International Nuclear Information System (INIS)

Chu, In-Cheol; Kwon, Tae-Soon; Song, Chul-Hwa

2008-01-01

Some evolutionary type PWRs such as APR1400 and APWR adopt advanced safety injection tank (SIT). The SIT of APR1400 has a fluidic device (FD) which passively controls ECC water injection flow rate into reactor coolant system during refill and reflood phases of LB-LOCA (i.e., a high injection flow rate during the refill phase and a low injection flow rate during the reflood phase). The benefit of the FD is the elimination of the function of low pressure safety injection pump from the safety injection system. The flow controlling performance of the APR1400 FD was evaluated using a prototypical full-scale test facility, called VAPER (Valve Performance Evaluation Rig). Even though the performance of the APR1400 FD satisfied major design and licensing requirements, further improvement of the performance is expected such as the extension of total injection period, the delay of nitrogen gas discharge. Several conceptual designs have been being drawn out in order to improve the performance of the APR1400 SIT. The performance of some designs was evaluated using a small scale SIT test rig. The present paper introduces some of the conceptual designs and shows the performance evaluation experimental results

Development of LBB Piping Evaluation Diagram for APR 1000 Main Steam Line Piping

International Nuclear Information System (INIS)

Yang, J. S.; Jeong, I. L.; Park, C. Y.; Bai, S. Y.

2010-01-01

This paper presents the piping evaluation diagram (PED) to assess the applicability of Leak-Before- Break(LBB) for APR 1000 main steam line piping. LBB-PED of APR 1000 main steam line piping is independent of its piping geometry and has a function of the loads applied in piping system. Also, in order to evaluate LBB applicability during construction process with only the comparative evaluation of material properties between actually used and expected, the expected changes of material properties are considered in the LBB-PED. The LBB-PED, therefore, can be used for quick LBB evaluation of APR 1000 main steam line piping of both design and construction

Review of APR+ Level 2 PSA

International Nuclear Information System (INIS)

Lehner, J.R.; Mubayi, V.; Pratt, W.T.

2012-01-01

Brookhaven National Laboratory (BNL) assisted the Korea Institute of Nuclear Safety (KINS) in reviewing the Level 2 Probabilistic Safety Assessment (PSA) of the APR+ Advanced Pressurized Water Reactor (PWR) prepared by the Korea Hydro and Nuclear Power Co., Ltd (KHNP) and KEPCO Engineering and Construction Co., Inc. (KEPCO-E and C). The work described in this report involves a review of the APR+ Level 2 PSA submittal (Ref. 1). The PSA and, therefore, the review is limited to consideration of accidents initiated by internal events. As part of the review process, the review team also developed three sets of Requests for Additional Information (RAIs). These RAIs were provided to KHNP and KEPCO-E and C for their evaluation and response. This final detailed report documents the review findings for each technical element of the PSA and includes consideration of all of the RAIs made by the reviewers as well as the associated responses. This final report was preceded by an interim report (Ref. 2) that focused on identifying important issues regarding the PSA. In addition, a final meeting on the project was held at BNL on November 21-22, 2011, where BNL and KINS reviewers discussed their preliminary review findings with KHNP and KEPCO-E and C staffs. Additional information obtained during this final meeting was also used to inform the review findings of this final report. The review focused not only on the robustness of the APR+ design to withstand severe accidents, but also on the capability and acceptability of the Level 2 PSA in terms of level of detail and completeness. The Korean nuclear regulatory authorities will decide whether the PSA is acceptable and the BNL review team is providing its comments for KINS consideration. Section 2.0 provides the basis for the BNL review. Section 3.0 presents the review of each technical element of the PSA. Conclusions and a summary are presented in Section 4.0. Section 5.0 contains the references.

Development of Nanosatellite Technology with APRS Module for Disaster Mitigation

Science.gov (United States)

Prahyang, S. Y.; Dhiya’Ulhaq, M. Z.; Golim, O. P.; Gunawan, R.; Suhandinata; Jahja, E.; Nelwan, E. R. G.; Ananta, C.; Chow, I. M.; Mali, N. D. F.

2018-05-01

Development of nanosatellite technology has enabled satellites to be developed with multiple capabilities for a specific mission in a short time with a low cost. Satellite communications are proved to be more effective in delivering information due to its large coverage area. Surya Satellite-1 will become the first Indonesian nanosatellite developed by undergraduate students. It is designed with low-cost commercial payloads, including an APRS module for communication and operated on VHF and UHF amateur radio frequencies. The mission of the satellites focused on disaster mitigation through APRS communication network with remote stations located on disaster-prone areas.

Probability Analysis of the Construction Cost of an APR1000 Single Unit

International Nuclear Information System (INIS)

Ha, Gak Hyeon; Suh, Yong Pyo; Kang, Yong Chul

2011-01-01

The nuclear power plant market is expected to grow rapidly in order to address issues of global warming, cutting CO 2 emissions and securing stable electricity supplies. Under these circumstances, the main primary goal of the APR1000 development is to ensure export competitiveness in the developing countries in the Middle East and Southeast Asia. To that end, APR1000 (1,000MWe, 3 rd generation) will be developed based on the OPR1000 (Korean standard nuclear power plant, 2.5 generation) by incorporating and improving the general requirements such as the 60 year design life time, comprehensive site requirement of 0.3g seismic design, stability improvement, operability improvement and provisions for severe accidents. The APR1000 adds 16 advanced design features to its predecessor, as outlined below in Table 1

Evaluation of the Main Steam Line Break Accident for the APR+ Standard Design using MARS-KS

Energy Technology Data Exchange (ETDEWEB)

Park, M. H.; Kim, Y. S.; Hwang, Min Jeong; Sim, S. K. [Environment Energy Technology, Daejeon (Korea, Republic of); Bang, Young Seok [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2015-05-15

As a part of licensing evaluation of the APR+ (Advanced Power Reactor +) standard design, Korea Institute of Nuclear Safety(KINS) performed safety evaluation of the APR+ Standard Safety Analysis Report(SSAR). The results of the safety evaluation of the APR+ Main Steam Line Break(MSLB) accident is presented for the most limiting post-trip return-to-power case with the single failure assumption of the Loss Of Offsite Power(LOOP). MARS-KS regulatory safety analysis code has been used to evaluate safety as well as the system behavior during MSLB accident. The MARS-KS analysis results are compared with the results of the MSLB safety analysis presented in the SSAR of the APR+. Independent safety evaluation has been performed using MARS-KS regulatory safety analysis code for the APR+ MSLB accident inside containment for the limiting case of the full power post-trip return-to-power. The results of MARS-KS analysis were compared with the results of the MSLB safety analysis presented in the APR+ SSAR. Due to higher cooldown of the MARS-KS analysis, the MARS-KS analysis results in a higher positive reactivity insertion into the core by the negative moderator and fuel temperature reactivity coefficients than the APR+ SSAR analysis. Both results show no return-to-power during the limiting case of the MSLB inside containment. However, APR+ SSAR moderator temperature reactivity insertion should be evaluated against the MARS-KS moderator density reactivity insertion for is conservatism. This study also clearly shows asymmetric thermal hydraulic behavior during the MSLB accident at intact and affected sides of the downcomer and the core. These asymmetric phenomena should be further investigated for the effects on the system design.

Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA

NARCIS (Netherlands)

Pel, Michiel J C; van Dijken, Anja J H; Bardoel, Bart W; Seidl, Michael F; van der Ent, Sjoerd; van Strijp, Jos A G; Pieterse, Corné M J

Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of

Pseudomonas syringae evades host Immunity by degrading flagellin monomers with alkaline protease AprA

NARCIS (Netherlands)

Pel, M.J.C.; Van Dijken, A.J.H.; Bardoel, B.W.; Seidl, M.F; Van der Ent, S.; Van Strijp, J.A.G.

2014-01-01

Bacterial flagellin molecules are strong inducers of innate immune responses in both mammals and plants. The opportunistic pathogen Pseudomonas aeruginosa secretes an alkaline protease called AprA that degrades flagellin monomers. Here, we show that AprA is widespread among a wide variety of

Quantitative Safety Impact of Severe Accident Management Systems for EU-APR during Low Power Shutdown Operation

International Nuclear Information System (INIS)

Lee, Keunsung; Hwang, Do Hun; Chang, Hyun-bin

2016-01-01

In order to enlarge and to diversify the export market of APR1400, the EU-APR design was developed based on the APR1400 design to comply with the latest version of the European Utility Requirements (EUR) revision D. The EU-APR design has the distinguished and advanced severe accident management systems taken from the APR1400 to obtain a containment integrity for the beyond design basis accident, such as the Passive Ex-vessel retaining and Cooling System (PECS), the Severe Accident Containment Spray System (SACSS) and the Containment Filtered Vent System (CFVS). The risk associated with the nuclear power plant can be identified through the Probabilistic Safety Assessment (PSA). In the EUR chapter 1 and 17 of volume 2, the Criteria for Limited Impact (CLI) should be applied to the Level 2 PSA as a risk metrics. The fraction of exceeding CLI for the EU-APR during LPSD operation was calculated as 4.52% of the CDF under the condition that all severe accident management systems are credited. The PECS, SACSS and CFVS are considered as the severe accident management system which is EU-APR dedicated system. The exemption of each system leads to increase the fraction of exceeding CLI to 54.18%, 89.74% and 21.32% respectively. In case if all these systems are unavailable, the fraction of exceeding CLI is increased to 100%. The most effective system is the SACSS that the system reduces containment pressure and temperature

Quantitative Safety Impact of Severe Accident Management Systems for EU-APR during Low Power Shutdown Operation

Energy Technology Data Exchange (ETDEWEB)

Lee, Keunsung; Hwang, Do Hun [KHNP CRI, Daejeon (Korea, Republic of); Chang, Hyun-bin [Future and Challenge Technology Co., Yongin (Korea, Republic of)

2016-10-15

In order to enlarge and to diversify the export market of APR1400, the EU-APR design was developed based on the APR1400 design to comply with the latest version of the European Utility Requirements (EUR) revision D. The EU-APR design has the distinguished and advanced severe accident management systems taken from the APR1400 to obtain a containment integrity for the beyond design basis accident, such as the Passive Ex-vessel retaining and Cooling System (PECS), the Severe Accident Containment Spray System (SACSS) and the Containment Filtered Vent System (CFVS). The risk associated with the nuclear power plant can be identified through the Probabilistic Safety Assessment (PSA). In the EUR chapter 1 and 17 of volume 2, the Criteria for Limited Impact (CLI) should be applied to the Level 2 PSA as a risk metrics. The fraction of exceeding CLI for the EU-APR during LPSD operation was calculated as 4.52% of the CDF under the condition that all severe accident management systems are credited. The PECS, SACSS and CFVS are considered as the severe accident management system which is EU-APR dedicated system. The exemption of each system leads to increase the fraction of exceeding CLI to 54.18%, 89.74% and 21.32% respectively. In case if all these systems are unavailable, the fraction of exceeding CLI is increased to 100%. The most effective system is the SACSS that the system reduces containment pressure and temperature.

Design features of Advanced Power Reactor (APR) 1400 steam generator

International Nuclear Information System (INIS)

Park, Tae-Jung; Park, Jun-Soo; Kim, Moo-Yong

2004-01-01

Advanced Power Reactor 1400 (APR 1400) which is to achieve the improvement of the safety and economical efficiency has been developed by Korea Hydro and Nuclear Power Co., Ltd. (KHNP) with the support from industries and research institutes. The steam generator for APR 1400 is an evolutionary type from System 80 + , which is the recirculating U-tube heat exchanger with integral economizer. Compared to the System 80 + steam generator, it is focused on the improved design features, operating and design conditions of APR 1400 steam generator. Especially, from the operation experience of Korean Standard Nuclear Power Plant (KSNP) steam generator, the lessons-learned measures are incorporated to prevent the tube wear caused by flow-induced vibration (FIV). The concepts for the preventive design features against FIV are categorized to two fields; flow distribution and dynamic response characteristics. From the standpoint of flow distribution characteristics, the egg-crate flow distribution plate (EFDP) is installed to prevent the local excessive flow loaded on the most susceptible tube to wear. The parametric study is performed to select the optimum design with the efficient mitigation of local excessive flow. ATHOS3 Mod-01 is used and partly modified to analyze the flow field of the APR 1400 steam generator. In addition, the upper tube bundle support is designed to eliminate the presence of tube with a low natural frequency. Based on the improved upper tube bundle support, the modal analysis is performed and compared with that of System 80 + . Using the results of flow distribution and modal analysis, the two mechanisms of flow-induced vibration are investigated; fluid-elastic instability (FEI) and random turbulence excitation (RTE). (authors)

Non-Integrated Standalone Tests of APR1400 Simulator

International Nuclear Information System (INIS)

Hwang, Su Hyun; Lee, Jeong Ik; Hong, Soon Joon; Lee, Byung Chul; Seo, Jeong Gwan; Lee, Myung Soo

2007-01-01

APR1400 being developed for the construction of New Kori 3 and 4 Units has improved safety and more economical efficiency compared with previous PWR. The ESF(Engineered Safety Features) newly introduced to enhance safety are as follows: DVI (Direct Vessel Injection), Fluidic Device, IRWST (In-containment Refueling Water Storage Tank). So the transient pattern of anticipated accidents will show different characteristics from previous PWR. There are multidimensional flow phenomena like as emergency core cooling coolant bypass discharge in the downcomer, downcomer boiling, and different safety injection characteristics due to fluidic device during LBLOCA. Also there is the phenomenon of critical flow due to the open of pressurizer POSRV (Pilot Operated Safety Relief valve) connected to IRWST and safety depressurization system and the prediction of discharge flow is very important. KEPRI is developing APR1400 simulator using RELAP-RT . RELAP-RT was developed by DS and S (Data systems and Solutions) based on RELAP5/MOD3.2. The improved features of RELAP-RT to function as a simulator are as follows: Add simulator functionality - Control by simulator executive - IC snap and reset capability - Back-track snap and reset capability - Fast time capability. Fast time capability(examples) - The rate of condensation has been limited. - Fictional choking model has been developed for internal junctions. - Wall heat transfer coefficients and heat fluxes has been limited. In this study, various NISTs (Non-Integrated Standalone Tests) were performed to verify the capability of RELAP-RT as APR1400 simulator by the comparison with RELAP5/MOD3.3

APR-246/PRIMA-1Met Inhibits and Reverses Squamous Metaplasia in Human Conjunctival Epithelium.

Science.gov (United States)

Li, Jing; Li, Cheng; Wang, Guoliang; Liu, Zhen; Chen, Pei; Yang, Qichen; Dong, Nuo; Wu, Huping; Liu, Zuguo; Li, Wei

2016-02-01

Squamous metaplasia is a common pathologic condition in ocular surface diseases for which there is no therapeutic medication in clinic. In this study, we investigated the effect of a small molecule, APR-246/PRIMA-1(Met), on squamous metaplasia in human conjunctival epithelium. Human conjunctival explants were cultured for up to 12 days under airlifting conditions. Epithelial cell differentiation and proliferation were assessed by Cytokeratin 10 (K10), K14, K19, Pax6, MUC5AC, and p63 immunostaining patterns. β-catenin and TCF-4 immunofluorescent staining and real-time PCR characterized Wnt signaling pathway involvement. Pterygium clinical samples were cultured under airlifting conditions with or without APR-246 for 4 days. p63, K10, β-catenin, and TCF-4 expression in pterygial epithelium was determined by immunofluorescent staining and real-time PCR. Airlift conjunctival explants resulted in increased stratification and intrastromal epithelial invagination. Such pathology was accompanied by increases in K10, K14, and p63 expression, whereas K19 and Pax6 levels declined when compared to those in freshly isolated tissue. On the other hand, APR-246 reversed all of these declines in K10, K14, and p63 expression. Furthermore, K19 and Pax6 increased along with rises in goblet cell density. These effects of APR-246 were accompanied by near restoration of normal conjunctival epithelial histology. APR-246 also reversed squamous metaplasia in pterygial epithelium that had developed after 4 days in ex vivo culture. Reductions in squamous metaplasia induced by APR-246 suggest it may provide a novel therapeutic approach in different squamous metaplasia-associated ocular surface diseases.

Preliminary Results Of LOCA Problem For APR1400 Reactor

International Nuclear Information System (INIS)

Le Dai Dien; Hoang Minh Giang; Le Thi Thu; Vo Thi Huong; Le Van Hong

2011-01-01

Several features of NPP with APR1400 nuclear reactor during a loss of coolant accident (LOCA) are investigated in this study. The report describes some main design characteristics of an engineering safety systems of APR1400 and the thermal hydraulic calculation results for steady-state using MARS and RELAP/SCDAPSIM codes. Large Break LOCA accident has been analyzed and evaluated based on acceptable criteria for ECCS given by US NRC. The results from cold leg break LOCA with broken area of 0.0465 m 2 in case of high pressure safety injection system (HPSI) failed to operate or 2 and 4 HPSI pumps are activated. The preliminary results of this work is a part of collaboration between INST researchers and KAERI experts in using RELAP tool for safety analysis of NPPs. (author)

The Ongoing Rediscovery of Après-Coup as a Central Freudian Concept.

Science.gov (United States)

House, Jonathan

2017-10-01

Après-coup, Freud's Nachträglichkeit, is an essential psychoanalytic concept structuring each of four concepts, four mental processes that lie at the foundation of Freud's thinking: psychic trauma, repression, the creation of the unconscious, and the creation of infantile sexuality. It is argued here that infantile sexual drives, in contrast to the self-preservative instincts, arise from a two-step process of translation and repression in which the residues of failed translation become source-objects of the drives. These residues of failed translation have an associative resonance with adult sexuality, and the child is driven to ongoing attempts to translate them, to make them meaningful après coup. Thus, après-coup is at the heart of the human subject as a sexual creature who requires, desires, and creates meaning.

Parole et identité humaine à l’âge classique

Directory of Open Access Journals (Sweden)

Pascale Gillot

2010-03-01

Full Text Available En prenant appui sur des textes de Descartes et de philosophes post-cartésiens comme Géraud de Cordemoy, ou encore des théoriciens de Port-Royal, tels Lancelot, Arnauld et Nicole, nous nous intéressons au statut double et paradoxal que revêt la parole dans la philosophie classique, au moment où se construit la question de l’union psychophysique et où sont proposées diverses « réponses » à cette question, dans la perspective d’une conceptualisation nouvelle d’une identité humaine rendue problématique. Le paradoxe tient au fait que l’activité de langage est d’abord manifestation de la pensée, indice publiquement observable ou témoignage extérieur de l’existence d’un esprit à l’origine des actes linguistiques, conformément à la théorie cartésienne à ce sujet ; mais la parole dénote aussi, dans la philosophie même de Descartes, une faculté spécifiquement humaine, propre au « vrai homme », en tant qu’il est indissolublement esprit et corps. Nous tentons de montrer que ce qui est en jeu dans les études brèves et éparses que Descartes consacre au langage, puis dans les développements ultérieurs de la Grammaire générale et raisonnée et de la Logique de Port-Royal, à travers la théorie du signe linguistique et de la signification, c’est la compréhension de la relation, nécessairement postulée et pourtant constamment renvoyée à l’ordre d’un lien contre-nature, et par là arbitraire, fruit d’une institution, entre la parole comme phénomène physique et la parole comme activité symbolique par excellence ; si bien que le prodige du phénomène humain du langage, comme expression publique des pensées, donne la mesure de l’énigme que constitue l’unité en l’homme du corps et de l’esprit.The aim of this paper is to lay emphasis on the connection between the mind-body problem and the theory of language which is developed in early-modern philosophy by Descartes and post

Deletion of aprA and nprA genes for alkaline protease A and neutral protease A from bacillus thuringiensis: effect on insecticidal crystal proteins.

Science.gov (United States)

Tan, Y; Donovan, W P

2001-11-17

The aprA gene encoding alkaline protease A (AprA) was cloned from Bacillus thuringiensis subsp. kurstaki, and the cloned gene was used to construct aprA-deleted (aprA1) strains of B. thuringiensis. An aprA1 strain of B. thuringiensis that contained the wild-type gene for neutral protease A (nprA(+)) displayed levels of extracellular proteolytic activity that were similar to those of an aprA(+)nprA(+) strain. However, when EDTA was included in the protease assay to inhibit NprA activity the aprA1nprA(+) strain displayed only 2% of the extracellular proteolytic activity of the aprA(+)nprA(+) strain. A strain that was deleted for both aprA and nprA (aprA1nprA3 strain) failed to produce detectable levels of proteolytic activity either in the presence or absence of EDTA in the assay. Compared with the aprA(+)nprA(+) strain the aprA1nprA(+) strain yielded 10% more full-length Cry1Bb crystal protein and the aprA1nprA3 strain yielded 25% more full-length Cry1Bb protein. No significant differences were seen in the 50% lethal dose of Cry1Bb protein from aprA(+)nprA(+) and aprA1nprA3 strains against three species of lepidopteran insects. These results suggest that enhanced yield of certain crystal proteins can be obtained by deletion of the genes aprA and nprA which are the major extracellular proteases of B. thuringiensis.

Development of the APR+ Auxiliary Building General Arrangement (GA)

International Nuclear Information System (INIS)

Moon, Hyung Keun; Park, Young Sheop; Kang, Yong Chul

2011-01-01

The general arrangement (GA) drawing of a nuclear power plant is the most basic drawing which contains all of the plant equipment, systems, and rooms. Therefore, it should be issued at an early design stage to provide the contours of the overall plant structure. This type of drawing is typically used widely throughout the design stages. The development project of APR+ (Advanced Power Reactor+), as a succeeding model of the APR1400 (Advanced Power Reactor 1400) design, has its own GA that encompasses all of its power buildings. This was developed starting in October of 2009. Among several of the buildings in this design, the Auxiliary Building (AB) is one of the most important buildings to produce electricity, and to protect against undesirable radiation emissions. This paper focuses on the design characteristics of the general arrangement of the AB

A Source Term Calculation for the APR1400 NSSS Auxiliary System Components Using the Modified SHIELD Code

International Nuclear Information System (INIS)

Park, Hong Sik; Kim, Min; Park, Seong Chan; Seo, Jong Tae; Kim, Eun Kee

2005-01-01

The SHIELD code has been used to calculate the source terms of NSSS Auxiliary System (comprising CVCS, SIS, and SCS) components of the OPR1000. Because the code had been developed based upon the SYSTEM80 design and the APR1400 NSSS Auxiliary System design is considerably changed from that of SYSTEM80 or OPR1000, the SHIELD code cannot be used directly for APR1400 radiation design. Thus the hand-calculation is needed for the portion of design changes using the results of the SHIELD code calculation. In this study, the SHIELD code is modified to incorporate the APR1400 design changes and the source term calculation is performed for the APR1400 NSSS Auxiliary System components

System Response Analysis of Rod Ejection Accident for APR1400 Using KNAP Hot Spot Model

International Nuclear Information System (INIS)

Kim, Yo-Han; Ha, Sang-Jun; Jun, Hwang-Yong

2006-01-01

Korea Electric Power Research Institute (KEPRI) has been developed the non-loss-of-coolant accident (non- LOCA) analysis methodology, called as the Korea Non- LOCA Analysis Package (KNAP), for the typical Optimized Power Reactor 1000 (OPR1000) plants. Considering current licensing methodology conducted by ABB-CE, however, the KNAP could be applied to Advanced Power Reactor 1400 (APR1400) also. In spite of some difference in design concepts of two plant types, there is a close resemblance between their nuclear steam supply systems (NSSS). So, in this study, the rod ejection accident (REA) event was analyzed using KNAP hot spot model (HSM) for APR1400 to estimate the feasibility of the application and the results were compared with those given in APR1400 Standard Safety Analysis Report (SSAR), which were calculated using the CESEC-III and STRIKIN-II code of ABB-CE. Through the study, it was concluded that the KNAP could be applicable to APR1400 on the view point of REA

Homology modeling of dissimilatory APS reductases (AprBA of sulfur-oxidizing and sulfate-reducing prokaryotes.

Directory of Open Access Journals (Sweden)

Birte Meyer

Full Text Available BACKGROUND: The dissimilatory adenosine-5'-phosphosulfate (APS reductase (cofactors flavin adenine dinucleotide, FAD, and two [4Fe-4S] centers catalyzes the transformation of APS to sulfite and AMP in sulfate-reducing prokaryotes (SRP; in sulfur-oxidizing bacteria (SOB it has been suggested to operate in the reverse direction. Recently, the three-dimensional structure of the Archaeoglobus fulgidus enzyme has been determined in different catalytically relevant states providing insights into its reaction cycle. METHODOLOGY/PRINCIPAL FINDINGS: Full-length AprBA sequences from 20 phylogenetically distinct SRP and SOB species were used for homology modeling. In general, the average accuracy of the calculated models was sufficiently good to allow a structural and functional comparison between the beta- and alpha-subunit structures (78.8-99.3% and 89.5-96.8% of the AprB and AprA main chain atoms, respectively, had root mean square deviations below 1 A with respect to the template structures. Besides their overall conformity, the SRP- and SOB-derived models revealed the existence of individual adaptations at the electron-transferring AprB protein surface presumably resulting from docking to different electron donor/acceptor proteins. These structural alterations correlated with the protein phylogeny (three major phylogenetic lineages: (1 SRP including LGT-affected Archaeoglobi and SOB of Apr lineage II, (2 crenarchaeal SRP Caldivirga and Pyrobaculum, and (3 SOB of the distinct Apr lineage I and the presence of potential APS reductase-interacting redox complexes. The almost identical protein matrices surrounding both [4Fe-4S] clusters, the FAD cofactor, the active site channel and center within the AprB/A models of SRP and SOB point to a highly similar catalytic process of APS reduction/sulfite oxidation independent of the metabolism type the APS reductase is involved in and the species it has been originated from. CONCLUSIONS: Based on the comparative

Constrained model predictive control for load-following operation of APR reactors

International Nuclear Information System (INIS)

Kim, Jae Hwan; Lee, Sim Won; Kim, Ju Hyun; Na, Man Gyun; Yu, Keuk Jong; Kim, Han Gon

2012-01-01

The load-following operation of APR+ reactor is needed to control the power effectively using the control rods and to restrain the reactivity control from using the boric acid for flexibility of plant operation. Usually, the reason why the disproportion of axial flux distribution occurs during load-following operation is xenon-induced oscillation. The xenon has a very high absorption cross-section and makes the impact on the reactor delayed by the iodine precursor. The power maneuvering using automatically load-following operation has advantage in terms of safety and economic operation of the reactor, so the controller has to be designed efficiently. Therefore, an advanced control method that meets the conditions such as automatic control, flexibility, safety, and convenience is necessary to load-following operation of APR+ reactor. In this paper, the constrained model predictive control (MPC) method is applied to design APR reactor's automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control. Some controllers use only the current tracking command, but MPC considers future commands in addition to the current tracking command. So, MPC can achieve better tracking performance than others. Furthermore, an MPC is to used in many industrial process control systems. The basic concept of the MPC is to solve an optimization problem for a finite future time interval at present time and to implement the first optimal control input as the current control input. The KISPAC-1D code, which models the APR+ nuclear power plants, is interfaced to the proposed controller to verify the tracking performance of the reactor power level and ASI. It is known that the proposed controller exhibits very fast tracking responses

Implementation and Analysis for APR1400 Soft Control System

International Nuclear Information System (INIS)

2015-01-01

Due to the rapid advancement of digital technology, the definite technical advantages of digital control system compared to analog control system are accelerating the implementation of advanced distributed digital control system in the nuclear power plant. One of the major advantages of digital control system is the capability of Soft Control System. The design of Soft Control System for Advanced Power Reactor 1400 (APR1400) plant of Man-Machine Interface System (MMIS) is based on full digital technologies to enhance reliability, operability and maintainability. Computer-based compact workstation has been adopted in the APR1400 Main Control Room (MCR) to provide convenient working environment. This paper introduces the approaches and methodologies of Soft Control System for the Advanced Control Room (ACR). This paper also explains major design features for operation and display of the Soft Control System and its implementation to cope with regulatory requirements. (authors)

Verbal Communication in the APR1400 Advanced Control Room

International Nuclear Information System (INIS)

Kim, Jong Hyun; Shin, Young Cheol

2007-01-01

This paper introduces the characteristics of communication in advanced main controlghd rooms (MCRs) and some observations from a case study performed for APR1400 MCR. In advanced MCRs, operators need not maintain the same communication patterns as they do in conventional ones. For example, a senior reactor operator (SRO) does not have to rely on board operators for information acquisition and can get any information from his/her own workstation. This situation may also bring about new problems in MCRs such as lack of shared situation awareness and collaboration between MCR operators. To cope with these problems, the APR1400 MCR adapts several approaches in design and training for encouraging operators to communicate with each other. This paper introduces the possible changes of communication patterns and the countermeasures in design and training. Some findings from an integrated system validation for Shin Kori Units 3 and 4 are also presented

Vingt ans après…

Directory of Open Access Journals (Sweden)

François Burgat

2002-05-01

Full Text Available Le dixième numéro des Chroniques Yéménites, publié vingt ans après la création du Centre Français d'Archéologie et de Sciences Sociales de Sanaa reflète des ambitions souvent exprimées: donner une chance aux jeunes chercheurs et couvrir un large éventail disciplinaire au service de l'affirmation de la vocation régionale du Centre. Depuis Sanaa ou Paris, chercheurs, doctorants ou stagiaires, de l'Ecole normale supérieure, de l'INALCO, de l'Université de Sanaa et de bon nombre d'institu...

Seismic analysis of APR1400 RCS for site envelope using big mass method

International Nuclear Information System (INIS)

Kim, J. Y.; Jeon, J. H.; Lee, D. H.; Park, S. H.

2002-01-01

One of design concepts of APR1400 is the site envelope considering various soil sites as well as rock site. The KSNP's are constructed on the rock site where only the translational excitations are directly transferred to the plant. On the other hand, the rotational motions affect the responses of the structures in the soil cases. In this study, a Big Mass Method is used to consider rotational motions as excitations at the foundation in addition to translational ones to obtain seismic responses of the APR1400 RCS main components. The seismic analyses for the APR1400 excited simultaneously by translation and rotational motions were performed. The results show that the effect of soil sites is not significant for the design of main components and supports of the RCS, but it may be considerable for the design of reactor vessel internals, piping, and nozzles which have lower natural frequencies

Preliminary Design of Optimized Reactor Insulator for Severe Accident Mitigation of APR1400

International Nuclear Information System (INIS)

Heo, Sun; Lee, Jae-Gon; Kang, Yong-Chul

2007-01-01

APR1400, a Korean evolutionary advance light water reactor, has many advanced safety feature to prevent and mitigate of design basis accident (DBA) and severe accident. When reactor cooling system (RCS) fails to cooling its core, the core melted down and the molten core gathers together on bottom of reactor vessel. The molten core hurts reactor vessel and is released to containment, which raises the release of radioactive isotopes and the heating of the containment atmosphere. Finally, the corium is accumulated in the bottom of reactor cavity and it also raises the Molten Core and Concrete Interaction (MCCI) and the heating of containment atmosphere. There are two strategies to cooling molten core. Those are in-vessel retention and ex-vessel cooling. At the early stage of APR1400 design, only ex-vessel cooling which is cooling of the molten core outside the vessel after vessel failure is considered based on EPRI Utility Requirement Document (URD) for Evolutionary LWR. However, a need has been arisen to reflect current research findings on severe accident phenomena and mitigation technologies to Korean URD and IVRERVC (In-Vessel corium Retention using Ex-Reactor Vessel Cooling) was adopted APR1400. The ERVC is not considered as a licensing design basis but based on the defense-in-depth principle and safety margin basis, which is the top-tier requirement of the severe accident mitigation design as stated in the KURD. The Severe Accident Management strategy for APR1400 is intended to aid the plant operating staff to secure reactor vessel integrity in the early stage of the severe accident. As a part of a design implementation of IVR-ERVC for APR1400, we developed the preliminary design requirement, design specification and conceptual design

Leadership et confiance développer le capital humain pour des organisations performantes

CERN Document Server

Duluc, Alain

2003-01-01

Aujourd'hui, l'encadrement des hommes consiste à tirer le meilleur parti de soi-même et des autres pour contribuer au développement de la performance. Ce type de leadership repose sur des valeurs telle qu'honnêteté, confiance, exemplarité, etc. Cet ouvrage propose une définition opérationnelle de ces valeurs et une façon de les mettre en ouvre. Il repose sur les méthodes et outils de développement personnel et organisationnel, élaborés par Will Schutz, un thérapeute américain. Sommaire : La complexité, nouveau passage des entreprises; Développer la confiance et la dimension humaine pour faire face à la complexité; Quelle forme de leadership pour demain?; Développer la confiance dans l'entreprise; La connaissance de soi et des autres, premier pas vers la confiance.

Single-tube condensation experiment in Passive Auxiliary Feedwater System of APR1400+

Energy Technology Data Exchange (ETDEWEB)

Shin, Chang Wook; No, Hee Cheon; Yun, Bong Yo; Jeon, Byong Guk [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

2012-05-15

Conventional Korean nuclear power plants, Advanced Power Reactors (APR), are characterized by an active cooling system. However, Active cooling system may not prevent significant damage without any AC power source available for its operation as vividly illustrated through the recent Fukushima incident. In the APR1400+ to be designed, an independent passive cooling system was added in order to overcome the aforementioned shortcomings. In the Passive Auxiliary Feedwater System (PAFS), gravity force and density difference between steam and water are used. The system comprises of 240 condensation tubes to efficiently remove decay heat. Before applying the PAFS to APR1400+, the system's safety and heat removal performance must be verified. The present study experimentally evaluates the heat removal performance of a single tube in the PAFS. The objectives of SCOP (Single-tube Condensation experiment facility of PAFS) are the evaluation of the heat removal performance in the tube of the PAFS and database construction under various tube designs and test conditions. Reaching these objectives, we developed advanced measurement techniques for the amount of moisture, heat flux, and water film thickness.

aprABC: A Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome

Science.gov (United States)

Abramovitch, Robert B.; Rohde, Kyle H.; Hsu, Fong-Fu; Russell, David G.

2011-01-01

Summary Following phagocytosis by macrophages, Mycobacterium tuberculosis (Mtb) senses the intracellular environment and remodels its gene expression for growth in the phagosome. We have identified an Acid and Phagosome Regulated (aprABC) locus that is unique to the Mtb complex and whose gene expression is induced during growth in acidic environments in vitro and in macrophages. Using the aprA promoter, we generated a strain that exhibits high levels of inducible fluorescence in response to growth in acidic medium in vitro and in macrophages. aprABC expression is dependent on the two-component regulator phoPR, linking phoPR signaling to pH sensing. Deletion of the aprABC locus causes defects in gene expression that impact aggregation, intracellular growth, and the relative levels of storage and cell wall lipids. We propose a model where phoPR senses the acidic pH of the phagosome and induces aprABC expression to fine-tune processes unique for intracellular adaptation of Mtb complex bacteria. PMID:21401735

Structural assessments of plate type support system for APR1400 reactor

Energy Technology Data Exchange (ETDEWEB)

Nguyen, Anh Tung; Namgung, Ihn, E-mail: inamgung@kings.ac.kr

2017-04-01

Highlights: • This paper investigates plate-type support structure for the reactor vessel of the APR 1400. • The tall column supports of APR1400 reactor challenges in seismic and severe accident events. • A plate-type support of reactor vessel was proposed and evaluated based on ASME code. • The plate-type support was assessed to show its higher rigidity than column-type. - Abstract: This paper investigates an alternative form of support structure for the reactor vessel of the APR 1400. The current reactor vessel adopts a four-column support arrangement locating on the cold legs of the vessel. Although having been successfully designed, the tall column structure challenges in seismic events. In addition, for the mitigation of severe accident consequences, the columns inhibit ex-vessel coolant flow, hence the elimination of the support columns proposes extra safety advantages. A plate-type support was proposed and evaluated for the adequacy of meeting the structural stiffness by Finite Element Analysis (FEA) approach. ASME Boiler and Pressure Vessel Code was used to verify the design. The results, which cover thermal and static structural analysis, show stresses are within allowable limits in accordance with the design code. Even the heat conduction area is increased for the plate-type of support system, the results showed that the thermal stresses are within allowable limits. A comparison of natural frequencies and mode shapes for column support and plate-type support were presented as well which showed higher fundamental frequencies for the plate-type support system resulting in greater rigidity of the support system. From the outcome of this research, the plate-type support is proven to be an alternative to current APR column type support design.

Simulation de mouvement humain sur postes de travail pour le diagnostic et l'aide à la conception

OpenAIRE

Hue, Valentin

2008-01-01

Les travaux présentés dans ce mémoire concernent la génération automatique de postures et mouvements humains sur poste de travail industriel. L'objectif poursuivi est d'animer de façon réaliste un mannequin numérique afin de simuler un opérateur dans l'exécution de sa tâche. Cette animation doit permettre d'aider à l'analyse des facteurs biomécaniques pouvant engendrer des Troubles Musculo-Squelettiques. Dans un premier temps, des choix de modélisation sont proposés en fonction de ce contexte...

Resultats visuels et complications apres chirurgie de la cataracte ...

African Journals Online (AJOL)

Resultats visuels et complications apres chirurgie de la cataracte: cas de l' Hopital Ophtalmologique Saint Andre de Tinre au nord-Benin. K.M. Amedome, C.R.A. Assavedo, M Aboudou, K Vonor, N Maneh, K Nonon Saa, K Dzidzinyo, K.D. Ayena, M Banla, K Balo ...

Containment Performance Analysis with Large Break LOCA for EU-APR1400

International Nuclear Information System (INIS)

Hwang, Do Hyun; Lee, Keun Sung; Kim, Yong Soo

2013-01-01

In this paper for containment performance analysis, the containment pressurization analysis is performed and thermo-hydraulic response analysis of containment structure is carried out to provide basic understanding of containment transient states under a severe accident sequence. Especially, in EU-APR1400 design, to reduce containment pressure and temperature, Severe Accident Containment Spray System (SACSS) is designed to be actuated automatically when Core Exit Temperature (CET) reaches 922 K (649 .deg. C). The containment performance analysis was carried on LBLOCA sequence for EU-APR1400 with SACSS through MAAP code. If SACSS is actuated when CET reaches 922 K (649 .deg. C) , the containment pressure and temperature decrease to a sufficient low level. The predicted atmospheric pressure of containment will not exceed the ultimate pressure capacity (UPC) and have a sufficient margin to it even though the UPC of the reference plant (Shin-Kori Units 3 and 4) is used instead because the UPC calculation for EU-APR1400 has not been completed. The largest load on the containment by LBLOCA is estimated at 306.1 kPa. Thus the margin to UPC is estimated to be 330 % in comparison with 1.329 MPa as UPC for the reference plant.

FORMER A L’EXERCICE D’UNE MEDECINE BIOTECHNOLOGIQUE ET HUMAINE

Directory of Open Access Journals (Sweden)

Jacques BRINGER

2017-05-01

Full Text Available Le bond en avant de la médecine au cours des dernières décennies s’est appuyé sur la recherche, l’innovation dans les nouvelles biotechnologies permettant le développement de soins plus efficaces, moins invasifs, mieux ciblés pour nombre de maladies. Dans le même temps, une meilleure gestion des risques et une organisation plus centrée sur le patient impliquent une étroite coopération entre les professionnels de santé activés selon les besoins du patient. Les étudiants en médecine doivent être entrainés à acquérir la pratique des nouvelles technologies et à se préparer à l’action en équipe avant d’intervenir dans le soin. Un tel entrainement par simulation vise à développer des mises en situation de « vraie vie » incluant l’obtention de compétences individuelles ou collectives et l’aptitude des cliniciens à une décision partagée et aux relations humaines telles que la capacité d’écoute, d’annonce et d’accompagnement s’appuyant sur le questionnement éthique et le souci de la personne.

MDEP Design-Specific Common Position CP-APR1400WG-01. Common position addressing Fukushima Daiichi nuclear power plant accident

International Nuclear Information System (INIS)

2016-05-01

The MDEP APR1400 Working Group (APR1400WG) members consist of members from Republic of Korea, United Arab Emirates, and the United States. A main objectives of MDEP is to encourage convergence of code, standard and safety goals with exploring the opportunities for harmonization of regulatory practice and cooperation on safety review of APR-1400 specific designs. This common position addressing is aimed at sharing knowledge, information and experience on safety improvement related to lessons learned from the Fukushima Daiichi NPP Accident or Fukushima Daiichi NPP Accident-related issues amongst APR-1400 WG member states to achieve the MEDP goal. Because not all of these Regulators have completed the regulatory review of their APR1400 applications yet, this paper identifies common preliminary approaches to address potential safety improvements for APR1400 plants, as well as common general expectations for new nuclear power plants, as related to lessons learned from the Fukushima Daiichi NPP Accident or Fukushima Daiichi NPP Accident-related issues. While some asymmetry exists among those of three Regulators in terms of design, regulatory practice and licensing milestone sharing information and common understanding on post-Fukushima Daiichi NPP Accident enhancement would be promote resilient design for countering beyond design extreme external event like Fukushima Daiichi NPP nuclear disaster. This common position paper aims at identifying characteristics of post-Fukushima Daiichi NPP Accident enhancements putting in place by each country and setting common position to achieve balanced and harmonized APR-1400 design. After the safety reviews of the APR1400 design applications that are currently in review are completed, the regulators will update this paper to reflect their safety conclusions regarding the APR1400 design and how the design could be enhanced to address Fukushima Daiichi NPP Accident-related issues. The common preliminary approaches are organised into

Uncertainty Evaluation of a Postulated LBLOCA for APR+ using KINS Realistic Evaluation Methodology and MARS-KS

Energy Technology Data Exchange (ETDEWEB)

Hwang, Min Jeong; Marigomena, Ralph; Yoo, Tae Ho; Kim, Y. S.; Sim, S. K. [Environment and Energy Technology, Inc., Daejeon (Korea, Republic of); Bang, Young Seok [KINS, Daejeon (Korea, Republic of)

2014-05-15

As a part of the regulatory safety research, Korea Institute of Nuclear Safety(KINS) also developed a best estimate safety analysis regulatory audit code, MARS-KS, to realistically predict and better understand the physical phenomena of the design basis accidents. KINS improved uncertainty propagation methodology using MARS-KS and applied the improved uncertainty evaluation method for the Shinkori Units 3 and 4 LBLOC. This study is to evaluate the uncertainty propagation of a postulated LBLOCA and quantify the safety margin using KINS-REM and MARS-KS code for the APR+ (Advanced Pressurizer Reactor Plus) Standard Safety Analysis Report(SSAR) which is under regulatory review by the KINS for its design approval. KINS-REM LBLOCA realistic evaluation methodology was used for the regulatory assessment of the APR+ LBLOCA using MARS-KS to evaluate the uncertainty propagation of the uncertainty variables as well as to assess the safety margin during the limiting case of the APR+ double ended guillotine cold leg LBLOCA. Uncertainty evaluation for the APR+ LBLOCA shows that the reflood PCT with upper limit of 95% probability at 95% confidence level is 1363.2 K and is higher than the blowdown PCT95/95 of 1275.3 K. The result shows that the current evaluation of APR+ LBLOCA PCT is within the acceptance criteria of 1477 K ECCS.

[Evaluation of the capacity of the APR-DRG classification system to predict hospital mortality].

Science.gov (United States)

De Marco, Maria Francesca; Lorenzoni, Luca; Addari, Piero; Nante, Nicola

2002-01-01

Inpatient mortality has increasingly been used as an hospital outcome measure. Comparing mortality rates across hospitals requires adjustment for patient risks before making inferences about quality of care based on patient outcomes. Therefore it is essential to dispose of well performing severity measures. The aim of this study is to evaluate the ability of the All Patient Refined DRG system to predict inpatient mortality for congestive heart failure, myocardial infarction, pneumonia and ischemic stroke. Administrative records were used in this analysis. We used two statistics methods to assess the ability of the APR-DRG to predict mortality: the area under the receiver operating characteristics curve (referred to as the c-statistic) and the Hosmer-Lemeshow test. The database for the study included 19,212 discharges for stroke, pneumonia, myocardial infarction and congestive heart failure from fifteen hospital participating in the Italian APR-DRG Project. A multivariate analysis was performed to predict mortality for each condition in study using age, sex and APR-DRG risk mortality subclass as independent variables. Inpatient mortality rate ranges from 9.7% (pneumonia) to 16.7% (stroke). Model discrimination, calculated using the c-statistic, was 0.91 for myocardial infarction, 0.68 for stroke, 0.78 for pneumonia and 0.71 for congestive heart failure. The model calibration assessed using the Hosmer-Leme-show test was quite good. The performance of the APR-DRG scheme when used on Italian hospital activity records is similar to that reported in literature and it seems to improve by adding age and sex to the model. The APR-DRG system does not completely capture the effects of these variables. In some cases, the better performance might be due to the inclusion of specific complications in the risk-of-mortality subclass assignment.

Design of a Load Following Controller for APR+ Nuclear Plants

International Nuclear Information System (INIS)

Lee, Sim Won; Kim, Jae Hwan; Kim, Dong Su; Na, Man Gyun; Yu, Keuk Jong

2011-01-01

The load-following operation of an APR+ nuclear plants is required to restrain the adjustment of boric acid concentration and to efficiently control the control rods for the flexibility of the operation. Especially, axial flux distribution disproportion that is usually caused by load-following operation in a reactor core induces xenon oscillation because the absorption cross-section of xenon is extremely large and its effects in a reactor are delayed by the iodine precursor. Rapid and smooth power maneuvering has its benefits in view of the economical and safe operation of reactors, so it is required that the controller is efficiently designed. Therefore, the load-following operation of an APR+ nuclear plants needs the ultimate automatic control and the advanced control method that satisfies the conditions such as the flexibility, safety and convenience. A model predictive control (MPC) method is applied to design an automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control for an APR+ nuclear plants. Some tracking controllers use only the current tracking command. On the other hand, since MPC considers future commands in addition to the current tracking command, the MPC can achieve better tracking performance. Therefore, the MPC has been applied very much to the control of industrial process systems. The basic concept of the MPC is to solve an optimization problem for generating finite future control inputs at current time and to implement as the current control input only the first control input among the solutions of the finite time steps. At the next time step, the second control input is not implemented and the procedure to solve the optimization problem is then repeated. The power level and the ASI are controlled by the regulating control banks and part-strength control banks together with the automatic adjustment of boric acid concentration. The 3-dimensional MASTER code, which models the APR+ nuclear

Design of a Load Following Controller for APR+ Nuclear Plants

Energy Technology Data Exchange (ETDEWEB)

Lee, Sim Won; Kim, Jae Hwan; Kim, Dong Su; Na, Man Gyun [Chosun University, Gwnagju (Korea, Republic of); Yu, Keuk Jong [Korea Hydro and Nuclear Power Co., Daejeon (Korea, Republic of)

2011-08-15

The load-following operation of an APR+ nuclear plants is required to restrain the adjustment of boric acid concentration and to efficiently control the control rods for the flexibility of the operation. Especially, axial flux distribution disproportion that is usually caused by load-following operation in a reactor core induces xenon oscillation because the absorption cross-section of xenon is extremely large and its effects in a reactor are delayed by the iodine precursor. Rapid and smooth power maneuvering has its benefits in view of the economical and safe operation of reactors, so it is required that the controller is efficiently designed. Therefore, the load-following operation of an APR+ nuclear plants needs the ultimate automatic control and the advanced control method that satisfies the conditions such as the flexibility, safety and convenience. A model predictive control (MPC) method is applied to design an automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control for an APR+ nuclear plants. Some tracking controllers use only the current tracking command. On the other hand, since MPC considers future commands in addition to the current tracking command, the MPC can achieve better tracking performance. Therefore, the MPC has been applied very much to the control of industrial process systems. The basic concept of the MPC is to solve an optimization problem for generating finite future control inputs at current time and to implement as the current control input only the first control input among the solutions of the finite time steps. At the next time step, the second control input is not implemented and the procedure to solve the optimization problem is then repeated. The power level and the ASI are controlled by the regulating control banks and part-strength control banks together with the automatic adjustment of boric acid concentration. The 3-dimensional MASTER code, which models the APR+ nuclear

The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods.

Science.gov (United States)

Kaplan, Bonnie J; Giesbrecht, Gerald F; Leung, Brenda M Y; Field, Catherine J; Dewey, Deborah; Bell, Rhonda C; Manca, Donna P; O'Beirne, Maeve; Johnston, David W; Pop, Victor J; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P; Eliasziw, Misha; McCargar, Linda J; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M; Letourneau, Nicole; Martin, Jonathan W

2014-01-01

The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offspring and many of their partners). The primary aims of the APrON study were to determine the relationships between maternal nutrient intake and status, before, during and after gestation, and (1) maternal mood; (2) birth and obstetric outcomes; and (3) infant neurodevelopment. We have collected comprehensive maternal nutrition, anthropometric, biological and mental health data at multiple points in the pregnancy and the post-partum period, as well as obstetrical, birth, health and neurodevelopmental outcomes of these pregnancies. The study continues to follow the infants through to 36 months of age. The current report describes the study design and methods, and findings of some pilot work. The APrON study is a significant resource with opportunities for collaboration. © 2012 John Wiley & Sons Ltd.

Veselības aprūpes iemaņas pusaudžiem bērnu namā

OpenAIRE

Zūpe, Daira

2008-01-01

Pētniecības darbā „Veselības aprūpes iemaņas pusaudžiem bērnu namā” autore Daira Zūpe izpēta un analizē vienu no bērnu namu aktuālajām problēmām veselības profilakses veicināšanā – veselības aprūpes iemaņu attīstīšanu. Pētījumā uzmanība pievērsta māsas lomai bērnu nama pusaudžu veselības aprūpes procesā, kur akcentēta veselības aprūpes pamatiemaņu nozīme veselības vecināšanā - fiziskās aktivitātes, ēšanas paradumi, kaitīgie ieradumi un higiēnas iemaņas. Pētniecības darba zinātniskā vadītā...

Aprūpes īpatnības bērniem ar Dauna sindromu stacionārā

OpenAIRE

Lūse, Ērika

2015-01-01

Bakalaura darba tēma – Aprūpes īpatnības bērniem ar Dauna sindromu stacionārā. Tēmas aktualitāte pievērst uzmanību bērna ar Dauna sindroma aprūpei, kā arī mazināt stereotipus par šiem bērniem. Darba mērķis ir izpētīt Dauna sindromu un māsas lomu šo bērnu aprūpē, kā arī aprūpes īpatnības. Pētniecības uzdevumi ir veikt zinātniskās literatūras analīzi, pētījuma atbilstošas māszinību teorijas atlasi, izstrādāt anketu, veikt pilot pētījumu, iegūto datu apkopošanu, analīze un secinājumu veikšana. I...

Thermo-mechanical Characterisation of In-plane Properties for CSM E-glass Epoxy Polymer Composite Materials

DEFF Research Database (Denmark)

Jakobsen, Johnny; Jensen, Martin; Andreasen, Jens Henrik

2013-01-01

The in-plane Young’s modulus of a CSM E-glass/epoxy material is characterised through the use of dynamic mechanical analysis (DMA). The measured data is used to generate material models which describe the property behaviour as a function of conversion and temperature. Gelation of the epoxy resin...... plays a major role in the modulus development and is measured directly on the glass/epoxy material. The Young’s modulus is described through a bi-functional model including the liquid/solid transition of the material. The evolution of Young’s modulus is modelled by decoupling modulus increments caused...... by time and temperature, and is graphically illustrated through a Modulus-Temperature- Transformation (MTT) diagram. Based on the established material models presented in this paper and models in Part-1, it is feasible to assess residual stresses and shape distortions of composite parts made from...

APR1400 Electrical Power System Conformance to SECY-91-078

Energy Technology Data Exchange (ETDEWEB)

Ha, Che-Wung; Kim, Yun-Ho [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

In this paper, the APR1400 electric power system for NRC-DC was described. In addition, the conformance to SECY 91-078 was evaluated. Enclosure 1 of the SECY provides an overview of the issue and states that the staff concludes that feeding the safety buses from the offsite power sources through non-safety buses or from a common transformer winding with non-safety loads is not the most reliable configuration. Such an arrangement increases the difficulty in properly regulating voltage at the safety buses, subjects the safety loads to transients caused by the non-safety loads, and adds additional failure points between the offsite power sources and safety loads. Therefore, it is the staff’s position that at least one offsite circuit to each redundant safety division should be supplied directly from one of the offsite power sources with no intervening non-safety buses, in such a manner that the offsite source can power the safety buses upon a failure of any non-safety bus. The APR1400 does not have an intervening nonsafety bus in the current offsite to onsite electrical configuration; however, the design does include nonsafety and safety buses coming from the same secondary side 4.16 kV transformer winding. Nevertheless, the APR1400 has designed the electrical interface system between offsite and onsite power with enhanced reliability measures to ensure that the nonsafety system will not impact the safety loads. The design complies with GDC 17 and also conforms to SECY-91-078.

Quality Control of Concrete Structure For APR1400 Construction

International Nuclear Information System (INIS)

Seo, Inseop; Song, Changhak; Kim, Duill

2012-01-01

Nuclear structure shall be constructed to protect internal facilities in the normal operation against external accidents such as the radiation shielding, earthquakes and to be leak-proof of radioactive substances to the external environment in case of loss of coolants. containment and auxiliary building of nuclear power plants are built in reinforced concrete structures to maintain these protection functions. Nuclear structures shall be designed to ensure soundness in operation since they are located on the waterfront where is easy do drain the cooling water and so deterioration and damage of concrete structures caused by seawater can occur. Durability is ensured for concrete structures of APR1400, a Korea standard NPP, in compliance with all safety requirements. In particular, owners perform quality control directly on the production and pouring of cast in place concrete for the concrete structure construction to make sure concrete structures established with quality homogeneity and durability. This report is to look into the quality control standard and management status of cast in place concrete for APR1400 construction

Study on Applicability of 10 CFR Part 21 to APR1400 DC Project

International Nuclear Information System (INIS)

Shin, He Young; Lee, Do Hwan; Lim, Jae Yong

2014-01-01

The tools such as NCR (non conformance report), CAR (corrective action request) and CAP (corrective action program) are widely used for that purpose based upon the rule of 10 CFR Part 50 Appendix B and the ASME Code NQA-1 requirements. These are the tools for a utility, as a purchaser taking over related basic components and services, to ensure strong quality assurance. During the conduct of the project for the acquisition of the standard design certification for APR1400 nuclear power plants from the U. S. NRC (APR1400 DC Project), a new CAP procedure that is appropriate to conduct this unique project was developed. However, it was also recommended to comply with the requirements under 10 CFR Part 21 which enhances nuclear safety quality assurances. Consequently, a new QA procedure is developed in order to deal with the 10 CFR Part 21 issues and this is integrated to the CAP procedure In this paper, the current corrective action program for the APR1400 DC project is introduced and the result of the study on the applicability of 10 CFR Part 21 to the project is indicated. In addition, further improving aspects to be considered are identified. As a frontier project to obtain the standard design certification for APR 1400 model from the U. S. NRC, a modified CAP procedure is developed and enhanced to deal with safety concerning issues in accordance with 10 CFR Part 21. In addition, the newly established QA procedure to directly control the reportability on 10 CFR Part 21 is interfaced into the existing CAP procedure

Assistant Personal Robot (APR: Conception and Application of a Tele-Operated Assisted Living Robot

Directory of Open Access Journals (Sweden)

Eduard Clotet

2016-04-01

Full Text Available This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot.

Apreçando Derivativos de Crédito no Brasil Credit Derivatives Pricing in Brazil

Directory of Open Access Journals (Sweden)

Jorge C. Kapotas

2004-12-01

Full Text Available Neste artigo apresentamos os principais modelos de apreçamento de instrumentos de crédito onde desenvolvem-se as equações de apreçamento de debêntures. Para tal, utilizam-se os modelos estruturais, de intensidade e, finalmente, de rating. A seguir, definimos o que são derivativos de crédito (CDS e derivamos fórmulas de apreçamento para estes instrumentos. Concluímos este artigo com uma aplicação ao mercado brasileiro. In this paper we present the main models used for pricing defaultable bonds and credit derivatives. The Merton structural model, the intensity framework and a Ratings based model are considered. We apply these techniques to the pricing of credit derivatives on Brazilian US$-indexed treasury bonds.

Écrire (d’après

Directory of Open Access Journals (Sweden)

Denis Saint-Amand

2009-03-01

Full Text Available De l’allusion à la citation, de l’emprunt criard au plagiat déguisé, les jeux d’influences et d’aller-retour avec tel ou tel modèle, grand ou mineur, ont toujours participé de l’élaboration du texte littéraire. Si l’intertextualité est sans aucun doute née en même temps que l’écriture (ou quelques minutes après et que, comme ont pu le montrer notamment Jacques-Philippe Saint-Gérand et Daniel Sangsue, les facettes multiples qu’elle déploie ont toujours suscité l’attention des hommes de lettre...

New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

Science.gov (United States)

Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

2015-01-01

Na-APR-1(M74) is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1(M74) and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1 wt in vitro, thereby providing proof of concept of Na-APR-1(M74) as a vaccine antigen. The mutated version, Na-APR-1(M74), was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1(M74) IgG. As little as 0.99 μg of recombinant Na-APR-1(M74) could induce anti Na-APR-1(M74) IgG in mice that were capable of inhibiting Na-APR-1w t-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1(M74) as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1 wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1(M74) which was assessed by fluorescence polarization, but with an ∼ 50-fold reduction in the dissociation constant. Taken together, these assays comprise a "toolbox" that could be useful for the analyses of Na-APR-1(M74) as it

Analytical Assessment of Environmental Impact for APR1400DC UHS Cooling Tower

Energy Technology Data Exchange (ETDEWEB)

Lee, Jaiho [KHNP-Central Research Institute, Daejeon (Korea, Republic of)

2015-05-15

Hot process water is pumped from the plant process to the cooling towers. Heat is rejected through evaporation of the process water, interacting with ambient air blown upward by fans.. Plumes generated from exit ports of the cooling tower may have adverse effects on the environment, such as deposition of cooling tower drift release, fogging, icing, shadowing, and ground-level temperature and humidity increase. These kinds of environmental impact of the cooling tower are linked closely with the dispersion of the cooling tower plumes. In this respect, predicting the behavior of the plumes has become one of the most important issues in the environmental assessments of the cooling towers. The SACTI (seasonal/annual cooling tower impact) model is an analytical tool to predict the environmental effect of cooling tower, which was developed by Argonne National Laboratory and University of Illinois with support from EPRI (electric power research institute). The initial version of SACTI has been widely used to assess the environmental effect of cooling towers in many industrial fields such as steam power plants and NPPs. Guo et. al. investigated impact of heat rejection and cooling tower height on plume dispersion using the SACTI model, for the purpose of the future construction of inland NPPs. They found that increasing cooling tower height decreases the plume length and height frequencies. Their simulation results showed that the increase in heat rejection increases the plum radius frequency. The APR1400DC is an advanced light water reactor developed for the purpose of NRC-DC (design certification). The cooling towers for APR1400DC UHS consist of two linear mechanical draft cooling towers (LMDCTs). The LMDCT for APR1400DC UHS is conceptually designed because the plant site has not been decided yet. In the present study, the dependency of plume dispersion on the number of cooling towers is investigated using SACTI-2-beta, for predicting annual environmental effect of APR

Effectiveness of External Reactor Vessel Cooling (ERVC) strategy for APR1400 and issues of phenomenological uncertainties

International Nuclear Information System (INIS)

Oh, S.J.; Kim, H.T.

2007-01-01

The APR1400(Advanced Power Reactor 1400) is an evolutionary advanced light water reactor with rated thermal power of 4000 MWt. For APR1400, External Reactor Vessel Cooling (ERVC) is adopted as a primary severe accident management strategy for in-vessel retention (IVR) of corium. The ERVC is a method of IVR by submerging the reactor vessel exterior. At the early stage of the APR1400 design, only ex-vessel cooling, cooling of the core melt outside the vessel after vessel is breached, is considered based on the EPRI Utility Requirement Document for Evolutionary LWR. However, based on the progress in implementation of Severe Accident Management Guidance (SAMG) for operating plants, as well as the research findings related to ERVC, ERVC strategy is adopted as a part of key severe accident management strategies. To improve its success, the strategy is reviewed and we implemented necessary design arrangement to increase its usefulness in managing the severe accident. In this paper, we examine the evolution of ERVC concept and its implementation in APR1400. Then, we review possible approach, including Risk-Oriented Accident Analysis Methodology (ROAAM), to evaluate the effectiveness of the strategy. (authors)

897.pdf | apr102004 | currsci | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; currsci; apr102004; 897.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

Implementasi Automatic Packet Reporting System (APRS Untuk Paket Data Pemantauan dan PengukuranUntuk Paket Data Pemantauan dan Pengukuran

Directory of Open Access Journals (Sweden)

Arief Goeritno

2016-03-01

Full Text Available Telah dilakukan implementasi Automatic Packet Reporting System (APRS untuk paket data pemantauan dan pengukuran melalui tujuan penelitian, berupa: a penyetelan program aplikasi pada jaringan APRS dan b pengukuran terhadap penerimaan data berdasarkan kinerja sensor-sensor. Penyetelan program aplikasi APRS merupakan konfigurasi perangkat lunak untuk APRS yang akan digunakan pada stasiun penerimaan data APRS dengan program aplikasi yang biasa digunakan, yaitu hyperterminal dan UI-View 32. Pengukuran penerimaan data berdasarkan kinerja sensor yang dilakukan melalui proses perekaman pada stasiun penerimaan data APRS. Kinerja sensor-sensor akan diamati pada stasiun pengiriman dan data hasil pengamatan akan dapat diterima pada stasiun penerimaan secara real time. Program aplikasi berbasis hyperterminal dan UI View 32 telah berhasil melakukan proses handshaking antara Terminal Node Controller (TNC dan komputer, sehingga data telemetri dari stasiun pengiriman paket data dapat diterima di stasiun penerimaan. Data telemetri dapat diamati pada stasiun penerimaan dan dapat diperoleh secara real time dengan format: YB0LRB-11>BEACON,WIDE2-1 [05/18/2014 04:03:49]: : T#010,008,093,004,122,075. Notifikasi YB0LRB-11 merupakan stasiun pengiriman paket data telemetri, kemudian data tersebut akan diterima pada stasiun penerima YD1PRY dengan format: YD1PRY-2>APLPN,ARISS [05/18/2014 04:03:07]: : !06.30.37S/106.48.26E#. Notifikasi tersebut merupakan pengiriman informasi data posisi oleh stasiun YD1PRY untuk inisialisasi pada jaringan APRS. Stasiun YB0LRB-11 ketika mengirim paket data telemetri dengan format: YB0LRB-11>BEACON,WIDE2-1 [05/18/2014 04:00:49]: : T#001,004,035,005,122,075. Paket data dari stasiun YB0LRB yang dipancar ulang atau digipeater dengan format: YB0LRB-11>BEACON,YD1PRY-2,WIDE2* [05/18/2014 04:00:50]: : T#001,004,035,005,122,075. Sensor pengukuran berkinerja relatif stabil, walaupun terdapat nilai simpangan pengukuran sebesar 1 cm atau

75 FR 44847 - Proposed Collection; Comment Request for Forms 943, 943-PR, 943-A, and 943A-PR

Science.gov (United States)

2010-07-29

... 943, 943-PR, 943- A, and 943A-PR AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and... comments concerning Forms 943, Employer's Annual Tax Return for Agricultural Employees, 943-PR, Planilla..., Agricultural Employer's Record of Federal Tax Liability, and 943A-PR, Registro De La Obligacion Contributiva...

Numerical Analysis of Molten Corium Dispersion during Hypothetical High-Pressure Accidents in APR1400 Nuclear Power Plant

International Nuclear Information System (INIS)

Kim, Jong Tae; Ha, Kwang Soon; Kim, Sang Baik; Kim, Hee Dong; Jeong, Jae Sik

2010-01-01

During a hypothetical high-pressure accident in a nuclear power plant (NPP), molten corium can be ejected through a breach of a reactor pressure vessel (RPV) and dispersed by the following jet of a high pressure steam in the RPV. The dispersed corium is fragmented into smaller droplets in a reactor cavity of the NPP by the steam jet with very high velocity and is released into the upper compartment of the NPP by an overpressure in the cavity. The heat-carrying fragments of the corium transfer the thermal energy to the ambient air in the containment and react chemically with steam and generate hydrogen which may be burnt in the containment. The thermal loads from the ejected molten corium on the containment which is called direct containment heating (DCH) can threaten the integrity of the containment. New generation NPPs such as APR1400 and EPR have been designed in consideration of reducing the possibility of the containment failure from the DCH. In order for that, APR1400 has a convolute-type corium chamber connected to the reactor cavity. In the case of EPR, severe-accident dedicated depressurization valves are installed to preclude a high pressure melt ejection (HPME). DCH in a NPP containment is related to many physical phenomena such as multi-phase hydrodynamics, thermodynamics and chemical reaction. In the evaluation of the DCH load, the melt dispersion rates depending on the RPV pressure are the most important parameter. Mostly, DCH was evaluated by using lumped-analysis codes with some correlations obtained from experiments for the dispersion rates. The corium dispersion rates for many types of the NPP containments had been obtained by experiments in 90s. And some correlations from the experimental data were developed. As mentioned above, APR1400 has a corium chamber to reduce the corium dispersion rate. But there is no experimental data for the dispersion rate specific to the APR1400 cavity geometry. So its performance for capturing of the dispersed corium

78 FR 47051 - Proposed Collection; Comment Request for Forms 943, 943-PR, 943-A, and 943A-PR

Science.gov (United States)

2013-08-02

... 943, 943-PR, 943- A, and 943A-PR AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and..., 943-PR, Planilla Para La Declarcion Anual De La Contribucion Federal Del Patrono De Empleados Agricolas, 943-A, Agricultural Employer's Record of Federal Tax Liability, and 943A-PR, Registro De La...

An Experimental Investigation on APR1400 Penetration Weld Failure by Metallic Melt

International Nuclear Information System (INIS)

An, Sang Mo; Ha, Kwang Soon; Kim, Hwan Yeol

2014-01-01

The penetrations are considered as the most vulnerable parts with respect to the reactor vessel failure when a core melt severe accident occurs and the corium reaches the lower head. Penetration tube failure modes can be divided into two categories; tube ejection out of the vessel lower head and rupture of the penetration tube outside the vessel. Tube ejection begins with degrading the penetration tube weld strength to zero as the weld is exposed to temperatures as high as the weld melting temperature, which is called weld failure, and then overcoming any binding force in the hole in the vessel wall that results from differential thermal expansion of the tube and vessel wall. Tube rupture assumes that the debris bed has melted the instrument tube inside the reactor and melt migrates down into the tube to a location outside the vessel wall where a pressure rupture can occur, thus breaching the pressure boundary. In the present paper, we have a focus on the tube ejection failure mode, specifically on the APR1400 weld failure by direct contact with a metallic melt. The objective is to investigate experimentally the ablation kinetics of an APR1400 penetration weld during the interactions with a metallic melt and to suggest the modification of the existing weld failure model. This paper involves the interaction experiments of two different metallic melts (metallic corium and stainless steel melts) with a weld specimen, and rough estimation of weld failure time. The interaction experiments between the metallic melts and an APR1400 penetration weld were performed to investigate the ablation kinetics of the penetration weld. Metallic corium and stainless steel melts were generated using an induction heating technique and interacted with a penetration weld specimen. The ablation rate of the weld specimen showed a range from 0.109 to 0..244 mm/s and thus the APR1400 penetration weld was estimated to be failed at hundreds of times after the interaction with the melt

Development of a Test Facility to Simulate the Reactor Flow Distribution of APR+

International Nuclear Information System (INIS)

Euh, D. J.; Cho, S.; Youn, Y. J.; Kim, J. T.; Kang, H. S.; Kwon, T. S.

2011-01-01

Recently a design of new reactor, APR+, is being developed, as an advanced type of APR1400. In order to analyze the thermal margin and hydraulic characteristics of APR+, quantification tests for flow and pressure distribution with a conservation of flow geometry are necessary. Hetsroni (1967) proposed four principal parameters for a hydraulic model representing a nuclear reactor prototype: geometry, relative roughness, Reynolds number, and Euler number. He concluded that the Euler number should be similar in the prototype and model under the preservation of the aspect ratio on the flow path. The effect of the Reynolds number at its higher values on the Euler number is rather small, since the dependency of the form and frictional loss coefficients on the Reynolds number is seen to be small. ABB-CE has carried out several reactor flow model test programs, mostly for its prototype reactors. A series of tests were conducted using a 3/16 scale reactor model. (see Lee et al., 2001). Lee et al (1991) performed experimental studies using a 1/5.03 scale reactor flow model of Yonggwang nuclear units 3 and 4. They showed that the measured data met the acceptance criteria and were suitable for their intended use in terms of performance and safety analyses. The design of current test facility was based on the conservation of Euler number which is a ratio of pressure drop to dynamic pressure with a sufficiently turbulent region having a high Reynolds number. By referring to the previous study, the APR+ design is linearly reduced to 1/5 ratio with a 1/2 of the velocity scale, which yields a 1/39.7 of Reynolds number scaling ratio. In the present study, the design feature of the facilities, named 'ACOP', in order to investigate flow and pressure distribution are described

Critical heat flux for APR1400 lower head vessel during a severe accident

International Nuclear Information System (INIS)

Noh, Sang W.; Suh, Kune Y.

2013-01-01

Highlights: ► Studied boiling on downward-facing hemispherical vessel with asymmetric thermal insulator. ► Scaled the APR1400 lower head linearly down by 1/10 including ICI tubes and shear keys. ► Performed thermal analysis using ANSYS V11.0 to determine the internal temperature and heat flux. ► Performed tests to obtain the CHF with saturated demineralized water at atmospheric pressure. ► Measured CHF accounting for 3D random flow effect expected in the APR1400 application. -- Abstract: Corium Ablation Stopper Apparatus (CASA) has a downward-facing hemispherical vessel and geometrically asymmetric thermal insulator of the Advanced Power Reactor 1400 MWe (APR1400) scaled linearly down by 1/10, as well as sixty-one in-core instrumentation (ICI) tubes and four shear keys. The heated vessel plays a pivotal role in CASA depending on the configuration of the oxide pool and metal layer to bring about the focusing effect expected of a molten pool in the lower head during a severe accident. The heated vessel was designed through a trial-and-error method and thermal analysis. Thermal analysis was performed using ANSYS V11.0 to investigate the effect of the internal temperature and heat flux on the integral hemispherical copper vessel. The CASA tests were carried out to obtain the critical heat flux (CHF) with saturated and demineralized water at the atmospheric pressure (0.1 MPa). The CHF in the metal layer through the hemispherical channel was found to be lower than that in the ULPU-2400 configuration V data through the streamlined thermal insulator. The experimental CHF was measured and obtained through the CASA hemispherical heated surface accounting for the three-dimensional random flow effect expected in the APR1400 application

Les perspectives nutritionnelles offertes par les OGM en alimentation humaine

Directory of Open Access Journals (Sweden)

Pascal Gérard

2004-03-01

Full Text Available Une étude des brevets récents, des publications scientifiques ainsi que des documents présentant les projets des firmes de biotechnologie constituent la base de cet article qui présente les perspectives de développement en alimentation humaine des organismes génétiquement modifiés (OGM présentant un intérêt nutritionnel. Si l’on trouve dans les brevets et les publications scientifiques des applications qui concernent l’amélioration ou l’enrichissement de la composition en macro- et micronutriments, ces applications restent curieusement à l’état de projets, très loin de la mise sur le marché. Les critiques aussi bien que les louanges dont sont l’objet les rares cas dont on pourrait envisager une mise en œuvre à moyen terme, comme le « riz doré », sont aussi injustifiées et excessives les unes que les autres. Les violentes polémiques autour des OGM risquent de handicaper le développement d’une technique puissante, qui n’est certes pas indispensable pour apporter une solution à l’éradication de la faim dans le monde, mais qui peut apporter des améliorations à la nutrition des populations, aussi bien des populations des pays en développement que des pays développés.

Evolution of glycaemia during irradiation syndrome; Evolution de la glycemie au cours du syndrome d'irradiation

Energy Technology Data Exchange (ETDEWEB)

Raisonnier, A [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

1967-03-15

The evolution of glycaemia following irradiation has been followed in the rat and pig. The results concerning a case of human accidental exposure have also been included. The author has tried to see whether the observed variations are reproducible and have a prognostic value. (author) [French] L'evolution de la glycemie a ete suivie, chez le rat et le porc, apres irradiation. Les resultats relatifs a une irradiation accidentelle humaine sont egalement rapportes. L'auteur cherche a definir si les variations observees sont reproductibles et ont une valeur pronostique. (auteur)

Evolution of glycaemia during irradiation syndrome; Evolution de la glycemie au cours du syndrome d'irradiation

Energy Technology Data Exchange (ETDEWEB)

Raisonnier, A. [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

1967-03-15

The evolution of glycaemia following irradiation has been followed in the rat and pig. The results concerning a case of human accidental exposure have also been included. The author has tried to see whether the observed variations are reproducible and have a prognostic value. (author) [French] L'evolution de la glycemie a ete suivie, chez le rat et le porc, apres irradiation. Les resultats relatifs a une irradiation accidentelle humaine sont egalement rapportes. L'auteur cherche a definir si les variations observees sont reproductibles et ont une valeur pronostique. (auteur)

Geneviève Cazes-Valette (dir., Faire la cuisine. Analyses pluridisciplinaires d’un nouvel espace de modernité

Directory of Open Access Journals (Sweden)

Pascale Moity-Maïzi

2007-05-01

Full Text Available Après Cuisines du monde, ouvrage anthropologique centré sur les techniques de transformation et de préparation alimentaires, Faire la cuisine nous offre un panorama pluridisciplinaire de regards sur la « cuisine » dans toutes ses dimensions possibles. De l’architecte au nutritionniste en passant par le sociologue, l’anthropologue, ou l’économiste, tous les regards sont permis sur cet espace-temps qui traverse notre histoire humaine et nos continents.Organisé en grandes sections, l’ouvrage pri...

Vibration Analysis for Steam Dryer of APR1400 Steam Generator

Energy Technology Data Exchange (ETDEWEB)

Han, Sung-heum; Ko, Doyoung [KHNP CRI, Daejeon (Korea, Republic of); Cho, Minki [Doosan Heavy Industry, Changwon (Korea, Republic of)

2016-10-15

This paper is related to comprehensive vibration assessment program for APR1400 steam generator internals. According to U.S. Nuclear Regulatory Commission, Regulatory Guide 1.20 (Rev.3, March 2007), we conducted vibration analysis for a steam dryer as the second steam separator of steam generator internals. The vibration analysis was performed at the 100 % power operating condition as the normal operation condition. The random hydraulic loads were calculated by the computational fluid dynamics and the structural responses were predicted by power spectral density analysis for the probabilistic method. In order to meet the recently revised U.S. NRC RG 1.20 Rev.3, the CVAP against the potential adverse flow effects in APR1400 SG internals should be performed. This study conducted the vibration response analysis for the SG steam dryer as the second moisture separator at the 100% power condition, and evaluated the structural integrity. The predicted alternating stress intensities were evaluated to have more than 17.78 times fatigue margin compared to the endurance limit.

Kalevipoeg tänapäeval - ühe tulevase Euroopa kultuuri document humain : psühholoogilis-antropoloogilisi aspekte / Peter Petersen ; tõlkinud Krista Räni

Index Scriptorium Estoniae

Petersen, Peter, 1933-

2003-01-01

Lisa 1. William Butler Yeats. Ta igatseb endale taevakangaid / tõlkinud Märt Väljataga, lk. 2587 ; Lisa 2. Novalis. Neue Fragmente. Nr. 393 (Novalis. Werke und Briefe. Stuttgart ; Hamburg : Deutscher Bücherbund, 1962), lk. 2587-2588 ; Lisa 3. Tabel väärtuste kohta, mida Kalevipoja-eeposes esile tuuakse, lk. 2588. Bibl. lk. 2589-2590. Tõlgitud käsikirjast: "Kalevipoeg heute - document humain einer künftigen Kultur Europas: psychologisch-anthropologische Aspekte"

GPM GROUND VALIDATION AIRBORNE SECOND GENERATION PRECIPITATION RADAR (APR-2) GCPEX V1

Data.gov (United States)

National Aeronautics and Space Administration — The GPM Ground Validation Airborne Second Generation Precipitation Radar (APR-2) GCPEx dataset was collected during the GPM Cold-season Precipitation Experiment...

1001.pdf | 25apr2010 | currsci | Indian Academy of Sciences

Indian Academy of Sciences (India)

2010-04-25

Apr 25, 2010 ... error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube · Twitter · Facebook · Blog. Academy News. IAS Logo. Summer Research Fellowship Programme 2018. Dates Extended To 7 December 2017. Register here · Focus Area Science ...

Improved Design of Crew Operation in Computerized Procedure System of APR1400

Energy Technology Data Exchange (ETDEWEB)

Seong, No Kyu; Jung, Yeon Sub; Sung, Chan Ho [KHNP, Daejeon (Korea, Republic of)

2016-05-15

The operators perform the paper-based procedures in analog-based conventional main control room (MCR) depending on only communications between operators except a procedure controller such as a Shift Supervisor (SS), however in digital-based MCR the operators can confirm the procedures simultaneously in own console when the procedure controller of computerized procedure (CP) opens the CP. The synchronization and a synchronization function between procedure controller and other operators has to be considered to support the function of crew operation. This paper suggests the improved design of crew operation in computerized procedure system of APR1400. This paper suggests the improved design of APR1400 CPS. These improvements can help operators perform the crew procedures more efficiently. And they reduce a burden of communication and misunderstanding of computerized procedures. These improvements can be applied to CPS after human factors engineering verification and validation.

Greta Kaits 9. apr. 1928 - 29. aug. 1946 : [luuletused] / Mats Traat

Index Scriptorium Estoniae

Traat, Mats, 1936-

2008-01-01

Sisu : Greta Kaits 9. apr. 1928 - 29. aug. 1946 ; Villem Hänilane 1898 - 1952 ; Peeter Pedak 1897 - 1953 ; Max Äidse 1903 - 1959 ; Lavinia Laidam ; Buchard Pruus ; Sergei Krivokopõtov ; Allan Luht 5. VII 1962 - 17. V 2007 ; Karl Saarmets 9. III 1924 - 14. IX 1981 ; Raimo Ritsik

Les pertes après récolte en Afrique : examen analytique et synthèse ...

International Development Research Centre (IDRC) Digital Library (Canada)

Partout en Afrique, les pertes après récolte le long de la chaîne alimentaire, de la ferme à la table, mettent en péril la sécurité alimentaire des agriculteurs dépourvus de ressources. La réduction des pertes après récolte peut aider à accroître la disponibilité, la qualité nutritionnelle et la salubrité des aliments, et à améliorer ...

Main steam line break accident simulation of APR1400 using the model of ATLAS facility

Science.gov (United States)

Ekariansyah, A. S.; Deswandri; Sunaryo, Geni R.

2018-02-01

A main steam line break simulation for APR1400 as an advanced design of PWR has been performed using the RELAP5 code. The simulation was conducted in a model of thermal-hydraulic test facility called as ATLAS, which represents a scaled down facility of the APR1400 design. The main steam line break event is described in a open-access safety report document, in which initial conditions and assumptionsfor the analysis were utilized in performing the simulation and analysis of the selected parameter. The objective of this work was to conduct a benchmark activities by comparing the simulation results of the CESEC-III code as a conservative approach code with the results of RELAP5 as a best-estimate code. Based on the simulation results, a general similarity in the behavior of selected parameters was observed between the two codes. However the degree of accuracy still needs further research an analysis by comparing with the other best-estimate code. Uncertainties arising from the ATLAS model should be minimized by taking into account much more specific data in developing the APR1400 model.

GPM GROUND VALIDATION AIRBORNE SECOND GENERATION PRECIPITATION RADAR (APR-2) GCPEX V1

Data.gov (United States)

National Aeronautics and Space Administration — The Second Generation Airborne Precipitation Radar (APR-2) is a dual-frequency (13 GHz and 35 GHz), Doppler, dual-polarization radar system. It has a downward...

The Gravity Makeup on the LORHR Event during Mid-loop Operation for APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, Cheol Woo; Lee, Yong Hee; Lee, Gyu Cheon; Kim, Shin Whan [KEPCO, Daejeon (Korea, Republic of)

2015-05-15

This paper is to investigate means of the available gravity makeup after the event to prevent or sustain the core uncovery and fuel failure for the typical advanced power reactor nuclear power plants (APR1400). Unlike the OPR1000 (optimized power reactor 1000 nuclear power plants), the refueling water storage tank of APR1400 cannot be used for gravity makeup since it is located on the bottom of the containment with a lower elevation than the reactor vessel. So, the other means of gravity makeup and their effect on the core uncovery are accounted. The use of the water used for the cask loading pit (CLP) during refueling or the safety injection line filling tank (SIFT), which are not designed for gravity makeup during the event, and safety injection tanks (SITs) are considered as the alternative source of makeup feed. The results show that gravity makeup of a SIT provides a sufficient operator action time for the LORHR with the station black out (SBO) during the mid-loop operation for the APR1400. From the LORHR event analysis, the effective means of gravity makeup for APR1400 to cope with this event concurrent loss of all AC power is determined as the gravity feed using SITs. Other means for gravity makeup using CLP or SIFT, which are not designed to mitigate the LORHR event, are evaluated as not effective to the event due to the large flow resistances and the low elevation head to overcome the system pressure increase during the LORHR. The use of one SIT and two SITs for the LORHR provides the core uncovery times as 3 hr 8 min and 4 hr 32 min extending 1 hr 15 min and 2 hr 38 min from the base case, respectively.

MELCOR code modeling for APR1400

Energy Technology Data Exchange (ETDEWEB)

Choi, Young; Park, S. Y.; Kim, D. H.; Ahn, K. I.; Song, Y. M.; Kim, S. D.; Park, J. H

2001-11-01

The severe accident phenomena of nuclear power plant have large uncertainties. For the retention of the containment integrity and improvement of nuclear reactor safety against severe accident, it is essential to understand severe accident phenomena and be able to access the accident progression accurately using computer code. Furthermore, it is important to attain a capability for developing technique and assessment tools for an advanced nuclear reactor design as well as for the severe accident prevention and mitigation. The objective of this report is to establish technical bases for an application of the MELCOR code to the Korean Next Generation Reactor (APR1400) by modeling the plant and analyzing plant steady state. This report shows the data and the input preparation for MELCOR code as well as state-state assessment results using MELCOR code.

Modalités d'occupation du territoire et relations humains-grands Carnivores durant le Pléistocène supérieur :Approche archéozoologique, taphonomique et paléoécologique du Bassin mosan dans son contexte nord-ouest européen

OpenAIRE

Jimenez, Elodie-Laure

2017-01-01

Au sein des territoires du nord-ouest européen, la Belgique et son Bassin mosan ont livré ces 150 dernières années une somme prodigieuse de témoins des populations humaines et animales paléolithiques. Alors que ces vestiges laissent supposer le caractère attractif de la région lors de la dernière glaciation du Pléistocène (115-10 ka BP), ces communautés d’ongulés et leurs prédateurs— humains et grands Carnivores — ont dû toutefois s’adapter à de nombreuses variations environne...

An investigation of major influences on the seismic response of APR1400 reactor vessel internals - 15145

International Nuclear Information System (INIS)

Byun, Y.J.; Kim, J.G.; Sung, K.K.; Lee, D.H.

2015-01-01

This paper deals with 3 topics concerning the APR1400 reactor vessel internals (RVI) seismic analysis: nonlinear problems, approaches to account for uncertainties of seismic model, and dynamic responses to various seismic excitations. First, the noticeable nonlinear characteristics of the RVI seismic model are discussed, and the modeling methods for properly simulating the nonlinear behaviors of RVI under seismic loads are presented. By applying these methods to the seismic model, the seismic analysis can correctly predict the dynamic response of RVI. Next, two approaches to account for the uncertainties of seismic model are evaluated: the time history broadening method, and the sensitivity analysis based on NUREG-0800, Section 4.2, Appendix A. From the evaluation results, it is confirmed that the time history broadening method employed in the seismic analysis of APR1400 RVI sufficiently accounts for the uncertainty of seismic model. Finally, the response characteristics of APR1400 RVI to various seismic excitations are investigated. The seismic excitations corresponding to various soil profiles, including the effects of cracked and un-cracked concrete stiffness on the reactor containment building structure, are used as forcing functions. From this study, the effects of various site conditions on the dynamic response of APR1400 RVI are identified. As a result, the enveloped seismic responses obtained from this study will contribute to the development of RVI seismic design that covers a wide range of potential site conditions. (authors)

967.pdf | 10apr2010 | currsci | Indian Academy of Sciences

Indian Academy of Sciences (India)

2010-04-10

Apr 10, 2010 ... error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held from 29–30 June 2018 ...

Phylogenetic Diversity of aprA Genes in Subseafloor Sediments on the Northwestern Pacific Margin off Japan.

Science.gov (United States)

Aoki, Masataka; Kakiuchi, Ryota; Yamaguchi, Takashi; Takai, Ken; Inagaki, Fumio; Imachi, Hiroyuki

2015-01-01

Markedly diverse sequences of the adenosine-5'-phosphosulfate reductase alpha subunit gene (aprA), which encodes a key enzyme in microbial sulfate reduction and sulfur oxidation, were detected in subseafloor sediments on the northwestern Pacific off Japan. The aprA gene sequences were grouped into 135 operational taxonomic units (90% sequence identity), including genes related to putative sulfur-oxidizing bacteria predominantly detected in sulfate-depleted deep sediments. Our results suggest that microbial ecosystems in the subseafloor biosphere have phylogenetically diverse genetic potentials to mediate cryptic sulfur cycles in sediments, even where sulfate is rarely present.

Application of Nuclear Application Programs to APR1400 Simulator

International Nuclear Information System (INIS)

Hwang, Do Hyun; Lee, Myeong Soo; Hong, Jin Hyuk

2012-01-01

Advanced Power Reactor 1400MWe (APR1400) simulator has been developed and installed at Kori Training Center for operators of ShinKori no.3, 4 nuclear power plant by Korea Hydro and Nuclear Power,s Central Research Institute (KHNP CRI). NAPS (Nuclear Application Programs) is a computerbased system which provides operators with past and real-time information for monitoring and controlling NSSS (Nuclear Steam Supply System), BOP (Balance Of Plant) and Electric system. NAPS consists of several programs such as COLSS (Core Operating Limit Supervisory System), SPADES+ (Safety Parameter Display and Evaluation System), CEA (Control Element Assembly) Application Program, and so on. Each program makes calculations based on its own algorithm and provides information available for operation. In order to use NAPS programs with a simulator even though they are being used in a real plant, they should be modified to add several simulation functions such as reset, snap, run/freeze and backtrack required by ANSI/ANS-3.5 to the original NAPS functionality. On top of that, interfacing programs should be developed for the data communication between respective NAPS programs and simulator sever. The purpose of this paper is to provide the overall architecture of the communication system between NAPS and simulator model, and to describe the method to apply NAPS to APR1400 simulator

Cold-Leg Small Break LOCA Analysis of APR1400 Plant Using a SPACE/sEM Code

International Nuclear Information System (INIS)

Lim, Sang Gyu; Lee, Suk Ho; Yu, Keuk Jong; Kim, Han Gon; Lee, Jae Yong

2013-01-01

The Small Break Loss-of-Coolant Accident (SBLOCA) evaluation methodology (EM) for APR1400, called sEM, is now being developed using SPACE code. SPACE/sEM is to set up a conservative evaluation methodology in accordance with appendix K of 10 CFR 50. Major required and acceptable features of the evaluation models are described as below. - Fission product decay : 1.2 times of ANS97 decay curve - Critical flow model : Henry-Fauske Moody two phase critical flow model - Metal-Water reaction model : Baker-Just equation - Critical Heat Flux (CHF) : B and W, Barnett and Modified Barnett correlation - Post-CHF : Groeneveld 5.7 film boiling correlation A series of test matrix is established to validate SPACE/sEM code in terms of major SBLOCA phenomena, e.g. core level swelling and boiling, core heat transfer, critical flow, loop seal clearance and their integrated effects. The separated effect tests (SETs) and integrated effect tests (IETs) are successfully performed and these results shows that SPACE/sEM code has a conservatism comparing with experimental data. Finally, plant calculations of SBLOCA for APR1400 are conducted as described below. - Break location sensitivity : DVI line, hot-leg, cold-leg, pump suction leg. - Break size spectrum : 0.4ft 2 ∼0.02ft 2 (DVI) 0.5ft 2 ∼0.02ft 2 (hot-leg, cold-leg, pump suction leg) This paper deals with break size spectrum analysis of cold-leg break accidents. Based on the calculation results, emergency core cooling system (ECCS) performances of APR1400 and typical SBLOCA phenomena can be evaluated. Cold-leg SBLOCA analysis for APR1400 is performed using SPACE/sEM code under harsh environment condition. SPACE/sEM code shows the typical SBLOCA behaviors and it is reasonably predicted. Although SPACE/sEM code has conservative models and correlations based on appendix K of 10 CFR 50, PCT does not exceed the requirement (1477 K). It is concluded that ECCS in APR1400 has a sufficient performance in cold-leg SBLOCA

Cold-Leg Small Break LOCA Analysis of APR1400 Plant Using a SPACE/sEM Code

Energy Technology Data Exchange (ETDEWEB)

Lim, Sang Gyu; Lee, Suk Ho; Yu, Keuk Jong; Kim, Han Gon; Lee, Jae Yong [Central Research Institute, KHNP, Ltd., Daejeon (Korea, Republic of)

2013-10-15

The Small Break Loss-of-Coolant Accident (SBLOCA) evaluation methodology (EM) for APR1400, called sEM, is now being developed using SPACE code. SPACE/sEM is to set up a conservative evaluation methodology in accordance with appendix K of 10 CFR 50. Major required and acceptable features of the evaluation models are described as below. - Fission product decay : 1.2 times of ANS97 decay curve - Critical flow model : Henry-Fauske Moody two phase critical flow model - Metal-Water reaction model : Baker-Just equation - Critical Heat Flux (CHF) : B and W, Barnett and Modified Barnett correlation - Post-CHF : Groeneveld 5.7 film boiling correlation A series of test matrix is established to validate SPACE/sEM code in terms of major SBLOCA phenomena, e.g. core level swelling and boiling, core heat transfer, critical flow, loop seal clearance and their integrated effects. The separated effect tests (SETs) and integrated effect tests (IETs) are successfully performed and these results shows that SPACE/sEM code has a conservatism comparing with experimental data. Finally, plant calculations of SBLOCA for APR1400 are conducted as described below. - Break location sensitivity : DVI line, hot-leg, cold-leg, pump suction leg. - Break size spectrum : 0.4ft{sup 2}∼0.02ft{sup 2}(DVI) 0.5ft{sup 2}∼0.02ft{sup 2}(hot-leg, cold-leg, pump suction leg) This paper deals with break size spectrum analysis of cold-leg break accidents. Based on the calculation results, emergency core cooling system (ECCS) performances of APR1400 and typical SBLOCA phenomena can be evaluated. Cold-leg SBLOCA analysis for APR1400 is performed using SPACE/sEM code under harsh environment condition. SPACE/sEM code shows the typical SBLOCA behaviors and it is reasonably predicted. Although SPACE/sEM code has conservative models and correlations based on appendix K of 10 CFR 50, PCT does not exceed the requirement (1477 K). It is concluded that ECCS in APR1400 has a sufficient performance in cold-leg SBLOCA.

Neuchatel ne gardera pas le Palais de l'equilibre apres Expo.02

CERN Multimedia

2002-01-01

"La ville de Neuchatel ne souhaite pas conserver le Palais de l'equilibre apres Expo.02. Par 24 voix contre 7, le Conseil general a rejete le plan special du Conseil communal qui proposait de transformer l'edifice en un centre de congres" (1/2 page).

Resilience engineering. Concepts and precepts de Hollnagel, Woods et Leveson

Directory of Open Access Journals (Sweden)

Jacques Leplat

2007-10-01

Full Text Available Le concept de résilience a conquis ces dernières années une large place dans les sciences humaines. Son étymologie et son histoire aident à comprendre ses « mille visages ». Après avoir trouvé sa place dans de nombreuses spécialités de la psychologie, il s’est introduit maintenant en ergonomie, notamment en rapport avec les recherches conduites dans le domaine de la sécurité, comme en témoigne cet ouvrage. Ce livre collectif rassemble en 12 chapitres les contributions de 25 auteurs, participa...

Avicenna. London, 2e éd., Routledge, 1995, 240 p., index.

OpenAIRE

Jambet, Christian

2010-01-01

Condenser la pensée d’Avicenne en un ouvrage bref est une gageure. Elle est ici tenue par l’A. qui, après une biographie détaillée, propose une belle analyse de la métaphysique, de l’eschatologie et de la rhétorique d’Avicenne. On regrettera seulement que quelques rapprochements aventureux (avec Hume, Descartes et surtout avec Kant) ne soient pas mieux fondés. Ils n’en sont pas moins suggestifs. Pages importantes sur le devenir de l’âme humaine (la question de son éventuelle divinisation) et ...

La représentation sociale de la culture de l'Autre : Figures opposées de l'Indien Primitif et du Maghrebin Indépendant chez des élèves de 1ère année d'IUT en situation de problème absurde

OpenAIRE

Maffiolo, Daniel

2006-01-01

Dans le cadre d'une intervention pédagogique, 47 élèves en 1ère année d'IUT sont soumis à un problème absurde de sciences humaines comparant un groupe de Maghrebins et un groupe de Zapotèques. Après avoir présenté les effets quantitatifs en termes de contrat de communication didactique, on propose une analyse qualitative intertextuelle des copies, mettant à jour la production collective d'une double représentation sociale opposant sous forme argumentative l'Indien Primitif au Maghrebin Indépe...

Progress of Design Improvements for APR1400 Computerized Procedure System from HFE V and V results and Design Experience

International Nuclear Information System (INIS)

Lee, Sungjin; Seong, Nokyu

2015-01-01

This study shows major already improved design features from the above three processes and a design proposal for to-be-improving items. APR1400 CPS has been verified and validated by the HFE process, internal design review and site acceptance tests. APR1400 Computerized Procedure System (CPS) has been applied to Shin-Kori Nuclear Power Plant (SKN) 3 and 4 units, Shin-Hanul Nuclear Power Plant (SHN) 1 and 2 units and Baraka Nuclear Power Plant (BNPP) 1, 2, 3 and 4 units. Since APR1400 CPS is a first-of-a-kind (FOAK) human machine interface (HMI) for executing a computerized procedure in the nuclear power plant's main control room in South Korea, it has been continuously improved through a) the human factor engineering (HFE) verification and validation (V and V), b) the internal design review and c) prototype tests. Human engineering discrepancies (HEDs) can be identified by the HFE V and V activity. Some HEDs of APR1400 CPS for SKN 3 and 4 and SHN 1 and 2 have been adopted as a role of design improvement in the CPS system while others were regarded as an operator training requirement or part of task contents. Various requests for improving the CPS have been collected from those results. A HMI system should be improved continuously for removing potential defects. Some of introduced design features in this paper has been adopted for APR1400 nuclear power plants. Some of them are under the review in the CPS design team of KHNP

Application of Standardized ITAAC to the APR1400 Design Certification

Energy Technology Data Exchange (ETDEWEB)

Kang, Deogji; Kim, Yunho [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

Design certification applications (DCAs) submitted pursuant to 10 CFR Part 52 contain two tiers of information, Tier 1 and Tier 2. Tier 1 contains information that is to be certified through rulemaking, and includes the inspections, tests, analyses, and acceptance criteria (ITAAC). Tier 2 contains more detailed information and is the source for information included in Tier1. DC applicants have developed the ITAAC with their own format and contents. This has caused the ineffectiveness of the review process by Nuclear Regulatory Commission (NRC) at the design certification stage. Standardizing the format and content of Tier 1 and ITAAC will achieve greater efficiency and effectiveness for Tier 1 and ITAAC development and NRC review, and for ITAAC implementation and verification. NRC provided the proposed standardized ITAAC for APR1400, and KHNP is considering the application of the proposed ITAAC. The strategy for application of the NRC proposed standardized ITAAC to the APR1400 design certification is now under developing, and a meeting with NRC to review the NRC proposed standardized ITAAC is expected to be held in the near future. In this review process, establishment of industry position on the NRC proposed standardized ITAAC is very important. The support from NEI and US industry is expected to be gained.

Application of Standardized ITAAC to the APR1400 Design Certification

International Nuclear Information System (INIS)

Kang, Deogji; Kim, Yunho

2016-01-01

Design certification applications (DCAs) submitted pursuant to 10 CFR Part 52 contain two tiers of information, Tier 1 and Tier 2. Tier 1 contains information that is to be certified through rulemaking, and includes the inspections, tests, analyses, and acceptance criteria (ITAAC). Tier 2 contains more detailed information and is the source for information included in Tier1. DC applicants have developed the ITAAC with their own format and contents. This has caused the ineffectiveness of the review process by Nuclear Regulatory Commission (NRC) at the design certification stage. Standardizing the format and content of Tier 1 and ITAAC will achieve greater efficiency and effectiveness for Tier 1 and ITAAC development and NRC review, and for ITAAC implementation and verification. NRC provided the proposed standardized ITAAC for APR1400, and KHNP is considering the application of the proposed ITAAC. The strategy for application of the NRC proposed standardized ITAAC to the APR1400 design certification is now under developing, and a meeting with NRC to review the NRC proposed standardized ITAAC is expected to be held in the near future. In this review process, establishment of industry position on the NRC proposed standardized ITAAC is very important. The support from NEI and US industry is expected to be gained

The comparison between layout and design of APR1400 MCR and EPRI requirement

International Nuclear Information System (INIS)

Suharyo Widagdo; Darlis; Sigit Santoso; T J Suryono

2013-01-01

A good man-machine interface system is needed by a nuclear power reactor because of its complexity and high safety factor. The man-machine interface system is centralized in the main control room (MCR). All of monitoring and controlling activity to keep the installation operation safety can be done from this place. In order to increase its ability in monitoring and controlling a hard effort to raise the interface system to the highest possible level is done not only by using the latest computer technology and instrumentation system but also using Human Engineering, as well. The paper aims to compare the lay out and design the APR1400 MCR and the requirement from EPRI about main control room lay out and design as response of TMI-2 accident. We can see from the discussion that the design of the MCR of APR1400 have been applied the request of EPRI. (author)

Effect of the design change of the LSSBP on core flow distribution of APR+ Reactor

International Nuclear Information System (INIS)

Kim, Kihwan; Euh, Dong-Jin; Choi, Hae-Seob; Kwon, Tae-Soon

2014-01-01

The uniform core inlet flow distribution of an Advanced Power Reactor Plus (APR+) is required to prevent the failure rate of the HIPER fuel assembly and improve the core thermal margin. KEPCO-E and C and KAERI proposed a design change of the Lower Support Structure Bottom Plate (LSSBP), since the core flow rates were intense near the outer region of the intact LSSBP in a previous study. In this study, an experiment was carried out to evaluate the effect of the design change of the LSSBP on the core flow distribution using the APR+ Core Flow and Pressure (ACOP) test facility. The results showed great improvement on the core flow distribution under a 4-pump balanced flow condition. Under the 4-pump balanced flow condition, fifteen tests were repeated using the ACOP test facility to verify the effect of the 50% blocked flow area at the outer region of the LSSBP on the core inlet flow distribution. The profiles of the core inlet mass flow rates were analyzed using ensemble averaged values, and compared with that of the intact LSSBP. The results showed great improvement for the overall core region. The change in design of the LSSBP is expected to improve the hydraulic performance of an APR+ reactor

Extended Station Blackout Analyses of an APR1400 with MARS-KS

International Nuclear Information System (INIS)

Kim, WoongBae; Jang, HyungWook; Oh, Seungjong; Lee, Sangyong

2016-01-01

The Fukushima Dai-ichi nuclear power plant accident shows that natural disasters such as earthquakes and the subsequent tsunamis can cause station blackout for several days. The electricity required for essential systems during a station blackout is provided from the emergency backup batteries installed at the nuclear power plant. In South Korea, in the event of an extended station blackout, the life of these emergency backup batteries has recently been extended from 8 hours to 24 hours at Shin-Kori 5, 6 and APR1400 for design certification. For a battery life of 24 hours, available safety means system, equipment and procedures are studied and analyzed in their ability to cope with an extended station blackout. A sensitivity study of reactor coolant pump seal leakage is performed to verify how different seal leakages could affect the system. For simulating of extended station blackout scenarios, the best estimate MARS-KS was used. In this paper, an APR1400 RELAP5 input deck was developed for station blackout scenario to analyze operation strategy by manually depressurizing the reactor coolant system through the steam generator's secondary side. Additionally, a sensitivity study was performed on reactor coolant pump seal leakage

Extended Station Blackout Analyses of an APR1400 with MARS-KS

Energy Technology Data Exchange (ETDEWEB)

Kim, WoongBae; Jang, HyungWook; Oh, Seungjong; Lee, Sangyong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2016-10-15

The Fukushima Dai-ichi nuclear power plant accident shows that natural disasters such as earthquakes and the subsequent tsunamis can cause station blackout for several days. The electricity required for essential systems during a station blackout is provided from the emergency backup batteries installed at the nuclear power plant. In South Korea, in the event of an extended station blackout, the life of these emergency backup batteries has recently been extended from 8 hours to 24 hours at Shin-Kori 5, 6 and APR1400 for design certification. For a battery life of 24 hours, available safety means system, equipment and procedures are studied and analyzed in their ability to cope with an extended station blackout. A sensitivity study of reactor coolant pump seal leakage is performed to verify how different seal leakages could affect the system. For simulating of extended station blackout scenarios, the best estimate MARS-KS was used. In this paper, an APR1400 RELAP5 input deck was developed for station blackout scenario to analyze operation strategy by manually depressurizing the reactor coolant system through the steam generator's secondary side. Additionally, a sensitivity study was performed on reactor coolant pump seal leakage.

Evaluation of Ablation rate by the change of Sacrificial Material for PECS in EU-APR

International Nuclear Information System (INIS)

Hwang, Do Hyun; Kim, Yong Soo; Lee, Keun Sung

2015-01-01

EU-APR, modified and improved from its original design of APR1400, has been developed to comply with European Utility Requirements (EUR) and nuclear design requirements of the European countries. In EU-APR, Severe Accident Mitigation Systems are dedicated to providing an independent defense line from that of Engineered Safety Feature (ESF) and Diverse Safety Feature (DSF). They consist of Emergency Reactor Depressurization System (ERDS), Passive Ex-vessel corium retaining and Cooling System (PECS), Severe Accident Containment Spray System (SACSS), Hydrogen Mitigation System (HMS) and Containment Filtered Vent System (CFVS). The PECS, so called core catcher, was introduced to prevent the Molten Core Concrete Interaction (MCCI) after Reactor Vessel (RV) failure. The PECS has experienced a lot of changes from its original design. Recently, the most significant change was that as a SM, limestone concrete is installed on PECS's body wall instead of previous sacrificial material rich in Fe 2 O 3 . The main reason of this design change is to overcome the issue that the sacrificial material is ablated rather too fast when reacting with corium that contains a large fraction of Zr metal. Other changes in the geometry of PECS's wall and downcomer design are considered as minor ones. In this paper, the comparison of ablation rates between previous SM and limestone concrete is carried out using MAAP5 code with respective MCCI model according to the material. In this paper, major improvements of MAAP5 model for PECS in EU-APR are presented and the evaluation of ablation rate for the previous SM model and the new LC model is carried out by means of ablation depths with LBLOCA sequence. Two models have respective unique ablation process. The ablation of LC model proceeds at a constant rate regardless of water while the ablation of SM model proceeds at a faster rate before the arrival of cooling water for corium and SM mixture. The change of sacrificial material also

Revision of the dosimetric parameters of the CSM11 LDR Cs-137 source.

Science.gov (United States)

Otal, Antonio; Martínez-Fernández, Juan Manuel; Granero, Domingo

2011-03-01

The clinical use of brachytherapy sources requires the existence of dosimetric data with enough of quality for the proper application of treatments in clinical practice. It has been found that the published data for the low dose rate CSM11 Cs-137 source lacks of smoothness in some regions because the data are too noisy. The purpose of this study was to calculate the dosimetric data for this source in order to provide quality dosimetric improvement of the existing dosimetric data of Ballester et al . [1]. In order to obtain the dose rate distributions Monte Carlo simulations were done using the GEANT4 code. A spherical phantom 40 cm in radius with the Cs-137 source located at the centre of the phantom was used. The results from Monte Carlo simulations were applied to derive AAPM Task Group 43 dosimetric parameters: anisotropy function, radial dose function, air kerma strength and dose rate constant. The dose rate constant obtained was 1.094 ± 0.002 cGy h -1 U -1 . The new calculated data agrees within experimental uncertainties with the existing data of Ballester et al . but without the statistical noise of that study. The obtained data presently fulfills all the requirements of the TG-43U1 update and thus it can be used in clinical practice.

The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates.

Directory of Open Access Journals (Sweden)

Ruth M Kennan

Full Text Available Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease that is characterized by the separation of the hoof from the underlying tissue. D. nodosus secretes three subtilisin-like proteases whose analysis forms the basis of diagnostic tests that differentiate between virulent and benign strains and have been postulated to play a role in virulence. We have constructed protease mutants of D. nodosus; their analysis in a sheep virulence model revealed that one of these enzymes, AprV2, was required for virulence. These studies challenge the previous hypothesis that the elastase activity of AprV2 is important for disease progression, since aprV2 mutants were virulent when complemented with aprB2, which encodes a variant that has impaired elastase activity. We have determined the crystal structures of both AprV2 and AprB2 and characterized the biological activity of these enzymes. These data reveal that an unusual extended disulphide-tethered loop functions as an exosite, mediating effective enzyme-substrate interactions. The disulphide bond and Tyr92, which was located at the exposed end of the loop, were functionally important. Bioinformatic analyses suggested that other pathogenic bacteria may have proteases that utilize a similar mechanism. In conclusion, we have used an integrated multidisciplinary combination of bacterial genetics, whole animal virulence trials in the original host, biochemical studies, and comprehensive analysis of crystal structures to provide the first definitive evidence that the extracellular secreted proteases produced by D. nodosus are required for virulence and to elucidate the molecular mechanism by which these proteases bind to their natural substrates. We postulate that this exosite mechanism may be used by proteases produced by

Trois modèles « éducatifs » : droit, potentialité et capital humain

Directory of Open Access Journals (Sweden)

Ingrid Robeyns

2011-05-01

Full Text Available Dans cet article, j’analyse trois logiques normatives qui peuvent fonder les politiques éducatives en portant une attention particulière aux questions liées aux spécificités des sexes. Ces trois modèles éducatifs sont la théorie du capital humain, le discours du droit et l’approche des potentialités. D’abord, je décris cinq rôles que l’éducation peut jouer. Ensuite, j’analyse les trois modèles pouvant fonder les politiques éducatives. La théorie du capital humain pose un certain nombre de problèmes parce qu’elle s’avère économiciste, fragmentée et essentiellement instrumentaliste. Le discours du droit et l’approche des potentialités sont en principe des modèles multidimensionnels et inclusifs et peuvent par le fait même tenir compte des rôles intrinsèques et non économicistes de l’éducation. Toutefois, selon la manière dont quelqu’un satisfait aux exigences spécifiques des cadres théoriques du droit et des potentialités, ceux-ci peuvent également présenter des difficultés. Je termine cet article en soutenant que la visée intrinsèque des politiques éducatives devrait être d’augmenter les potentialités des individus et que nous devrions employer les discours du droit de façon stratégique, c’est-à-dire lorsqu’il est probable qu’ils amènent les gens à réaliser leurs potentialités.In this paper, I discuss three normative approaches that can establish educational policies with special attention to gender issues. These three models of education are human capital theory, the discourse of law and the capabilities theory. First, I describe five roles that education can play. Then I analyze the three foundational models of educational policies. The human capital theory raises a number of problems because it is economistic, fragmented and largely instrumental. The discourse of law and the capabilites theory are usually multidimensional and inclusive; they can thereby take into account

Investigation of the Condensation Effect at IRWST Pool Surface on Containment Back Pressure in APR1400 Containment

International Nuclear Information System (INIS)

Lee, Eui Jong; Lee, Jin Yong; Lee, Byung Chul

2006-01-01

The APR1400 has several new design concepts in order to improve the plant safety functions during a postulated accident. The In-Containment Refueling Water Storage Tank (IRWST) is one of the new design concepts of APR1400 and installed at the bottom of containment building to promote the plant safety functions by simplifying emergency core cooling water source and preventing release of the fission product during an accidents. This design feature, however, brings about uncertainty factors which may necessitate conventional prediction of temperature and pressure of containment building improved or revised under accident conditions. The hot steam which is released from RCS break enters into the IRWST through four Pressure Relief Dampers (PRDs). It is expected to be condensed with water stored in IRWST, colder than incoming steam. The purpose of this study is to examine closely the influence of the condensation effect at IRWST on containment back pressure in APR1400 containment building using the GOTHIC code which can predict the steam condensation on IRWST pool surface

La gestion des ressources humaines peut-elle être un facteur de fidélisation de la clientèle du centre E. Leclerc Casteldis ?

OpenAIRE

Laurie Ple

2010-01-01

Le secteur de la grande distribution est un domaine passionnant par son histoire, son évolution et sa place au cœur de nombreuses mutations de notre société. L'explorer à travers la gestion des ressources humaines est tout de suite paru attirant. Étant donné que la grande distribution évolue dans un contexte de plus en plus compétitif, la fidélisation de la clientèle est devenue un de ses grands enjeux. La grande distribution a développé des outils de fidélisation, mais ils sont largement rep...

The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study : rationale and methods

NARCIS (Netherlands)

Kaplan, Bonnie J.; Giesbrecht, Gerald F.; Leung, Brenda M. Y.; Field, Catherine J.; Dewey, Deborah; Bell, Rhonda C.; Manca, Donna P.; O'Beirne, Maeve; Johnston, David W.; Pop, Victor J.; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P.; Eliasziw, Misha; McCargar, Linda J.; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M.; Letourneau, Nicole; Martin, Jonathan W.

The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their

The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study : Rationale and methods

NARCIS (Netherlands)

Kaplan, B.J.; Giesbrecht, G.F.; Leung, B.M.; Field, C.J.; Dewey, D.; Bell, R.C.; Manca, D.P.; O'Beirne, M.; Johnston, D.W.; Pop, V.J.M.; Singhal, N.; Gagnon, L.; Bernier, F.P.; Eliasziw, M.; McCargar, L.J.; Kooistra, L.; Farmer, A.; Cantell, M.; Goonewardene, L.; Casey, L.M.; Letourneau, N.; Martin, J.W.

2014-01-01

The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their

Calculation of fuel and moderator temperature coefficients in APR1400 nuclear reactor by MVP code

International Nuclear Information System (INIS)

Pham Tuan Nam; Le Thi Thu; Nguyen Huu Tiep; Tran Viet Phu

2014-01-01

In this project, these fuel and moderator temperature coefficients were calculated in APR1400 nuclear reactor by MVP code. APR1400 is an advanced water pressurized reactor, that was researched and developed by Korea Experts, its electric power is 1400 MW. The neutronics calculations of full core is very important to analysis and assess a reactor. Results of these calculation is input data for thermal-hydraulics calculations, such as fuel and moderator temperature coefficients. These factors describe the self-safety characteristics of nuclear reactor. After obtaining these reactivity parameters, they were used to re-run the thermal hydraulics calculations in LOCA and RIA accidents. These thermal-hydraulics results were used to analysis effects of reactor physics parameters to thermal hydraulics situation in nuclear reactors. (author)

The effect of nodalization and temperature of reactor upper region: Sensitivity analysis for APR-1400 LBLOCA

International Nuclear Information System (INIS)

Kang, Dong Gu

2017-01-01

Highlights: • The nodalization of APR-1400 was modified to reflect the characteristic of upper region temperature. • The effect of nodalization and temperature of reactor upper region on LBLOCA consequence was evaluated. • The modification of nodalization is an essential prerequisite in APR-1400 LBLOCA analysis. - Abstract: In best estimate (BE) calculation, the definition of system nodalization is important step influencing the prediction accuracy for specific thermal-hydraulic phenomena. The upper region of reactor is defined as the region of the upper guide structure (UGS) and upper dome. It has been assumed that the temperature of upper region is close to average temperature in most large break loss of coolant accident (LBLOCA) analysis cases. However, it was recently found that the temperature of upper region of APR-1400 reactor might be little lower than or similar to hot leg temperature through the review of detailed design data. In this study, the nodalization of APR-1400 was modified to reflect the characteristic of upper region temperature, and the effect of nodalization and temperature of reactor upper region on LBLOCA consequence was evaluated by sensitivity analysis including best estimate plus uncertainty (BEPU) calculation. In basecase calculation, in case of modified version, the peak cladding temperature (PCT) in blowdown phase became higher and the blowdown quenching (or cooling) was significantly deteriorated as compared to original case, and as a result, the cladding temperature in reflood phase became higher and the final quenching was also delayed. In addition, thermal-hydraulic parameters were compared and analyzed to investigate the effect of change of upper region on cladding temperature. In BEPU analysis, the 95 percentile PCT used in current regulatory practice was increased due to the modification of upper region nodalization, and it occurred in the reflood phase unlike original case.

Seismic analysis of the APR1400 nuclear reactor system using a verified beam element model

Energy Technology Data Exchange (ETDEWEB)

Park, Jong-beom [Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722 (Korea, Republic of); Park, No-Cheol, E-mail: pnch@yonsei.ac.kr [Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722 (Korea, Republic of); Lee, Sang-Jeong; Park, Young-Pil [Department of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722 (Korea, Republic of); Choi, Youngin [Korea Institute of Nuclear Safety, 62 Gwahak-ro, Yuseong-gu, Daejeon 34142 (Korea, Republic of)

2017-03-15

Highlights: • A simplified beam element model is constructed based on the real dynamic characteristics of the APR1400. • Time history analysis is performed to calculate the seismic responses of the structures. • Large deformations can be observed at the in-phase mode of reactor vessel and core support barrel. - Abstract: Structural integrity is the first priority in the design of nuclear reactor internal structures. In particular, nuclear reactor internals should be designed to endure external forces, such as those due to earthquakes. Many researchers have performed finite element analyses to meet these design requirements. Generally, a seismic analysis model should reflect the dynamic characteristics of the target system. However, seismic analysis based on the finite element method requires long computation times as well as huge storage space. In this research, a beam element model was developed and confirmed based on the real dynamic characteristics of an advanced pressurized water nuclear reactor 1400 (APR1400) system. That verification process enhances the accuracy of the finite element analysis using the beam elements, remarkably. Also, the beam element model reduces seismic analysis costs. Therefore, the beam element model was used to perform the seismic analysis. Then, the safety of the APR1400 was assessed based on a seismic analysis of the time history responses of its structures. Thus, efficient, accurate seismic analysis was demonstrated using the proposed beam element model.

Seismic analysis of the APR1400 nuclear reactor system using a verified beam element model

International Nuclear Information System (INIS)

Park, Jong-beom; Park, No-Cheol; Lee, Sang-Jeong; Park, Young-Pil; Choi, Youngin

2017-01-01

Highlights: • A simplified beam element model is constructed based on the real dynamic characteristics of the APR1400. • Time history analysis is performed to calculate the seismic responses of the structures. • Large deformations can be observed at the in-phase mode of reactor vessel and core support barrel. - Abstract: Structural integrity is the first priority in the design of nuclear reactor internal structures. In particular, nuclear reactor internals should be designed to endure external forces, such as those due to earthquakes. Many researchers have performed finite element analyses to meet these design requirements. Generally, a seismic analysis model should reflect the dynamic characteristics of the target system. However, seismic analysis based on the finite element method requires long computation times as well as huge storage space. In this research, a beam element model was developed and confirmed based on the real dynamic characteristics of an advanced pressurized water nuclear reactor 1400 (APR1400) system. That verification process enhances the accuracy of the finite element analysis using the beam elements, remarkably. Also, the beam element model reduces seismic analysis costs. Therefore, the beam element model was used to perform the seismic analysis. Then, the safety of the APR1400 was assessed based on a seismic analysis of the time history responses of its structures. Thus, efficient, accurate seismic analysis was demonstrated using the proposed beam element model.

Characterisation of the thermostable protease AprX in strains of Pseudomonas fluorescens and impact on the shelf-life of dairy products: preliminary results

Directory of Open Access Journals (Sweden)

Nadia Andrea Andreani

2016-12-01

Full Text Available Bacterial proteases are involved in food spoilage and shelf-life reduction. Among the bacterial proteases, a predominant role in spoilage of dairy products seems to be played by the thermostable metallo-protease AprX, which is produced by various strains of Pseudomonas fluorescens. Differences in AprX enzyme activity among different strains were highlighted, but the most proteolytic strains were not identified. In this study, the presence of the aprX gene was evaluated in 69 strains isolated from food matrices and 18 reference strains belonging to the P. fluorescens group, which had been previously typed by the multi locus sequence typing method. Subsequently, a subset of reference strains was inoculated in ultra-high temperature milk, and the expression of the aprX gene was evaluated at 22 and 6°C. On the same milk samples, the proteolytic activity was then evaluated through Azocasein and trinitrobenzenesulfonic acid solution assays. Finally, to assess the applicability of the former assay directly on dairy products the proteolityc activity was tested on industrial ricotta samples using the Azocasein assay. These results demonstrate the spread of aprX gene in most strains tested and the applicability of Azocasein assay to monitor the proteolytic activity in dairy products.

Complex regulation of AprA metalloprotease in Pseudomonas fluorescens M114: evidence for the involvement of iron, the ECF sigma factor, PbrA and pseudobactin M114 siderophore.

Science.gov (United States)

Maunsell, Bláithín; Adams, Claire; O'Gara, Fergal

2006-01-01

In the soil bacterium Pseudomonas fluorescens M114, extracellular proteolytic activity and fluorescent siderophore (pseudobactin M114) production were previously shown to be co-ordinately negatively regulated in response to environmental iron levels. An iron-starvation extracytoplasmic function sigma factor, PbrA, required for the transcription of siderophore biosynthetic genes, was also implicated in M114 protease regulation. The current study centred on the characterization and genetic regulation of the gene(s) responsible for protease production in M114. A serralysin-type metalloprotease gene, aprA, was identified and found to encode the major, if not only, extracellular protease produced by this strain. The expression of aprA and its protein product were found to be subject to complex regulation. Transcription analysis confirmed that PbrA was required for full aprA transcription under low iron conditions, while the ferric uptake regulator, Fur, was implicated in aprA repression under high iron conditions. Interestingly, the iron regulation of AprA was dependent on culture conditions, with PbrA-independent AprA-mediated proteolytic activity observed on skim milk agar supplemented with yeast extract, when supplied with iron or purified pseudobactin M114. These effects were not observed on skim milk agar without yeast extract. PbrA-independent aprA expression was also observed from a truncated transcriptional fusion when grown in sucrose asparagine tryptone broth supplied with iron or purified pseudobactin M114. Thus, experimental evidence suggested that iron mediated its effects via transcriptional activation by PbrA under low iron conditions, while an as-yet-unidentified sigma factor(s) may be required for the PbrA-independent aprA expression and AprA proteolytic activity induced by siderophore and iron.

Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine.

Science.gov (United States)

Seid, Christopher A; Curti, Elena; Jones, R Mark; Hudspeth, Elissa; Rezende, Wanderson; Pollet, Jeroen; Center, Lori; Versteeg, Leroy; Pritchard, Sonya; Musiychuk, Konstantin; Yusibov, Vidadi; Hotez, Peter J; Bottazzi, Maria Elena

2015-01-01

Over 400 million people living in the world's poorest developing nations are infected with hookworms, mostly of the genus Necator americanus. A bivalent human hookworm vaccine composed of the Necator americanus Glutathione S-Transferase-1 (Na-GST-1) and the Necator americanus Aspartic Protease-1 (Na-APR-1 (M74)) is currently under development by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP). Both monovalent vaccines are currently in Phase 1 trials. Both Na-GST-1 and Na-APR-1 antigens are expressed as recombinant proteins. While Na-GST-1 was found to express with high yields in Pichia pastoris, the level of expression of Na-APR-1 in this host was too low to be suitable for a manufacturing process. When the tobacco plant Nicotiana benthamiana was evaluated as an expression system, acceptable levels of solubility, yield, and stability were attained. Observed expression levels of Na-APR-1 (M74) using this system are ∼300 mg/kg. Here we describe the achievements and obstacles encountered during process development as well as characterization and stability of the purified Na-APR-1 (M74) protein and formulated vaccine. The expression, purification and analysis of purified Na-APR-1 (M74) protein obtained from representative 5 kg reproducibility runs performed to qualify the Na-APR-1 (M74) production process is also presented. This process has been successfully transferred to a pilot plant and a 50 kg scale manufacturing campaign under current Good Manufacturing Practice (cGMP) has been performed. The 50 kg run has provided a sufficient amount of protein to support the ongoing hookworm vaccine development program of the Sabin PDP.

Extended station blackout analyses of an APR1400 with MARS-KS

Directory of Open Access Journals (Sweden)

Kim Woongbae

2016-01-01

Full Text Available The Fukushima Daiichi nuclear power plant accident shows that natural disasters such as earthquakes and the subsequent tsunamis can cause station blackout for several days. The electric energy required for essential systems during a station blackout is provided from emergency backup batteries installed at the nuclear power plant. In South Korea, in the event of an extended station blackout, the life of these emergency backup batteries has recently been extended from 8 hours to 24 hours at Shin-Kori 5, 6, and APR1400 for design certification. For a battery life of 24 hours, available safety means system, equipment and procedures are studied and analyzed in their ability to cope with an extended station blackout. A sensitivity study of reactor coolant pump seal leakage is performed to verify how different seal leakages could affect the system. For simulating extended station blackout scenarios, the best estimate MARS-KS computer code was used. In this paper, an APR1400 RELAP5 input deck was developed for station blackout scenario to analyze operation strategy by manually depressurizing the reactor coolant system through the steam generator's secondary side. Additionally, a sensitivity study on reactor coolant pump seal leakage was carried out.

Evaluation of Ablation rate by the change of Sacrificial Material for PECS in EU-APR

Energy Technology Data Exchange (ETDEWEB)

Hwang, Do Hyun; Kim, Yong Soo; Lee, Keun Sung [KHNP-CRI, Daejeon (Korea, Republic of)

2015-05-15

EU-APR, modified and improved from its original design of APR1400, has been developed to comply with European Utility Requirements (EUR) and nuclear design requirements of the European countries. In EU-APR, Severe Accident Mitigation Systems are dedicated to providing an independent defense line from that of Engineered Safety Feature (ESF) and Diverse Safety Feature (DSF). They consist of Emergency Reactor Depressurization System (ERDS), Passive Ex-vessel corium retaining and Cooling System (PECS), Severe Accident Containment Spray System (SACSS), Hydrogen Mitigation System (HMS) and Containment Filtered Vent System (CFVS). The PECS, so called core catcher, was introduced to prevent the Molten Core Concrete Interaction (MCCI) after Reactor Vessel (RV) failure. The PECS has experienced a lot of changes from its original design. Recently, the most significant change was that as a SM, limestone concrete is installed on PECS's body wall instead of previous sacrificial material rich in Fe{sub 2}O{sub 3}. The main reason of this design change is to overcome the issue that the sacrificial material is ablated rather too fast when reacting with corium that contains a large fraction of Zr metal. Other changes in the geometry of PECS's wall and downcomer design are considered as minor ones. In this paper, the comparison of ablation rates between previous SM and limestone concrete is carried out using MAAP5 code with respective MCCI model according to the material. In this paper, major improvements of MAAP5 model for PECS in EU-APR are presented and the evaluation of ablation rate for the previous SM model and the new LC model is carried out by means of ablation depths with LBLOCA sequence. Two models have respective unique ablation process. The ablation of LC model proceeds at a constant rate regardless of water while the ablation of SM model proceeds at a faster rate before the arrival of cooling water for corium and SM mixture. The change of sacrificial material

Outcomes of patients with abdominoperineal resection (APR) and low anterior resection (LAR) who had very low rectal cancer.

Science.gov (United States)

Yeom, Seung-Seop; Park, In Ja; Jung, Sung Woo; Oh, Se Heon; Lee, Jong Lyul; Yoon, Yong Sik; Kim, Chan Wook; Lim, Seok-Byung; Kim, Nayoung; Yu, Chang Sik; Kim, Jin Cheon

2017-10-01

We compared the oncological outcomes of sphincter-saving resection (SSR) and abdominoperineal resection (APR) in 409 consecutive patients with very low rectal cancer (i.e., tumors within 3 cm from the anal verge); 335 (81.9%) patients underwent APR and 74 (18.1%) underwent SSR. The APR group comprised higher proportions of men (67.5% vs 55.4%, P = .049) and advanced-stage patients (P cancer stages. RFS was associated with ypT and ypN stages in patients who received PCRT, while pN stage, lymphovascular invasion (LVI), and circumferential resection margin (CRM) involvement were risk factors for RFS in those who did not receive PCRT. Notably, SSR was not found to be a risk factor for RFS in either subgroup. Patients who were stratified according to cancer stage and PCRT also showed no differences in RFS according to the mode of surgery. Our results demonstrate that, regardless of PCRT administration, SSR is an effective treatment for very low rectal cancer, while CRM is an important prognostic factor for patients who did not receive PCRT.

Development of phenomena identification and ranking table for APR1400 main steam line break

International Nuclear Information System (INIS)

Song, J. H.; Chung, B. D.; Jeong, J. J.

2003-01-01

A Phenomena Identification and Ranking Table (PIRT) was developed for the Main Steam Line Break (MSLB) event of an APR-1400 (Advanced Power Reactor-1400). A team of experts from research institutes, industries, and regulatory bodies participated in the development. The selected event was a double-ended steam line break at full power with the reactor coolant pump running. The panel selected the fuel performance as the primary safety criterion for ranking. The plant design data, the results of APR-1400 safety analysis, and the results of additional best estimate analysis by MARS2.1 were utilized. Three phases of pre-trip, rapid cool-down, and safety injection phase were identified. Then, the ranking of a system, components, phenomenon/process based on the relative importance to the primary evaluation criterion were followed for each time phase. Finally, the knowledge-level for each important process in the component was ranked in terms of the existing knowledge. The highly ranked phenomena identified for APR-1400 MSLB are tube wall heat transfer at the steam generator shell, void distribution at the steam generator shell, liquid entrainment in the separators, mixture level in the separators, boron mixing in the upper down comer, boron transport and thermal mixing in the lower plenum, stored energy release in the upper head, and flow to and/from the upper head. The PIRT will be used as a guide in planning cost effective experimental programs and code development efforts, especially for the quantification of the process and/or phenomena, which have a high importance but low knowledge level

Le corps sexué au cœur du politique - Dépendances et Justice sociale

OpenAIRE

Gardien, Eve

2012-01-01

Article; International audience; Avec la définition du concept de santé sexuelle en 1974, l'OMS a mis en avant la part de responsabilité de nos sociétés dans l'état de bonne ou mauvaise santé sexuelle des populations. La sexualité sort ainsi du champ de l'intime et se pose la question de la justice sociale. Après un détour pour appréhender la part de l'environnement social dans l'apprentissage des techniques sexuelles, le développement des corps humains et la production des situations de dépe...

Simulation du mouvement humain en vue d'applications ergonomiques - Vers une approche de simulation basée sur données et assistée par connaissances

OpenAIRE

WANG, X

2003-01-01

Le mannequin numérique, comme outil de conception, a pour objectif de permettre aux ingénieurs de prendre en compte des facteurs humains dans la conception de produits ou de postes de travail. Il doit être capable de représenter le futur opérateur ou l'utilisateur du produit, de simuler son activité, d'évaluer ses interactions avec son environnement et d'en déduire des informations sur les astreintes subies. Si les avancées technologiques, notamment dans le domaine informatique, permettent un...

Conflito étnico, direitos humanos e intervenção internacional

Directory of Open Access Journals (Sweden)

Tullo Vigevani

2008-01-01

Full Text Available Dans cet article, on examine comment les conflits ethniques atteignent de façon négative les droits de l'homme et comment a lieu l'intervention internationale en vue de la défense de ces droits. Pour cela, on oppose la structure qui déclenche des conflits ethniques et un cadre idéal où l'État serait capable d'assurer l'exercice des droits humains, selon l’optique soutenue par les Nations Unies. Ainsi, à mesure qu'on dénonce les points où ce genre de conflit mine les fondements de ces droits, on construit un deuxième cadre où ils ne sont pas assurés, et c'est là que se pose la question de l'intervention humanitaire. Enfin, on observe que, malgré l'importance des droits humains dans l'après-Guerre Froide, ils ne forment pas une association d'objectifs. Il faut donc, pour comprendre les critères de sélection qui commandent les interventions humanitaires, prendre en compte d'autres intérêts.

Face au risque

CERN Document Server

Grosse, Christian; November, Valérie

2007-01-01

Ce volume collectif sur le risque inaugure la collection L'ÉQUINOXE. Ancré dans l'histoire pour mesurer les continuités et les ruptures, il illustre la manière dont les sciences humaines évaluent et mesurent les enjeux collectifs du risque sur les plans politiques, scientifiques, énergétiques, juridiques et éthiques. Puisse-t-il nourrir la réflexion sur la culture et la prévention du risque. Ses formes épidémiques, écologiques, sociales, terroristes et militaires nourrissent les peurs actuelles, structurent les projets sécuritaires et constituent - sans doute - les défis majeurs à notre modernité. Dans la foulée de la richesse scientifique d'Equinoxe, L'ÉQUINOXE hérite de son esprit en prenant à son tour le pari de contribuer - non sans risque - à enrichir en Suisse romande et ailleurs le champ éditorial des sciences humaines dont notre société a besoin pour forger ses repères. Après Face au risque suivra cet automne Du sens des Lumières. (MICHEL PORRET Professeur Ordinaire à la F...

RÉGIME FISCAL DES MEMBRES DU PERSONNEL EN FRANCE: DÉCLARATION DES REVENUS 2002 - French version only

CERN Multimedia

2003-01-01

http://cern.ch/hr-div/internal/generalinfo/impots/impots_fr.asp IMPORTANT 1) Les autorités fiscales françaises ont informé l'Organisation de certaines modifications concernant le régime fiscal applicable à certains membres du personnel du CERN domiciliés en France. La Direction générale du CERN tente actuellement de clarifier certaines modalités d'application de ces mesures. Pour le moment, les membres du personnel résidant en France sont priés de se conformer aux instructions ci-après, ainsi qu'à celles qui seront éventuellement publiées en la matière au cours de l'année 2003. 2) Pour faire face à l'augmentation des demandes de consultation, la Division des Ressources humaines a mis en place un service de "première orientation" ("help desk") au 72838 qui vous adressera vers les services internes ou extérieurs compétents. Cependant, la Division des Ressources humaines ne pouvant se substituer aux autorités fiscales et ne disposant pas des ressources nécessaires pour traiter l'ensemble ...

Evaluation of Coolant Injection Procedure in the Severe Accident Management Strategy of APR1400

International Nuclear Information System (INIS)

Cho, Yongjin; Lim, Kukhee; Song, Sungchu; Lee, Sukho; Hwang, Taesuk

2013-01-01

A coolant injection strategy in the severe accident management guideline (SAMG) of APR1400 relates to immediate coolant injection into RCS (Reactor Coolant System) or injection following the recovery of secondary coolant inventory. This strategy could play important role in accident mitigation and radiological consequences. In this study, appropriateness of the strategy was evaluated using MELCOR1.8.6 and several sensitivity studies of the key parameters were performed. Analysis for APR1400 using MELCOR 1.8.6 was performed to evaluate the effectiveness of accident management strategies and the following conclusions were identified. Sequential operation of secondary and RCS injection may not be the best strategy and the simultaneous injection of secondary and RCS injection could be more preferable. At least, the RCS injection should start before complete drainage of water in the safety injection tank using mobile pumps. In this study, the effectiveness of timing of operator action has been examined and the amount of injection flowrate needs to be studied in the future

Simplified study for the proposed APR1400 condenser performance based on EL-DABAA SITE, EGYPT, with respect to BNPP and SHIN KORI NPP

Energy Technology Data Exchange (ETDEWEB)

Abdoelatef, M. Gomaa; Rezk, Osama; Lee, YonKwan [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2015-10-15

• Perception of nuclear power as a convenient, economically competitive and viable source of energy which, if introduced in the country, would not only complement the traditional energy sources, but would also promote technological development and serve as an incentive for social and economic progress. In this paper we will introduce APR-1400 as the most likely selected reactor type for 1st Egyptian Nuclear Power Plant. Then we will study the optimized APR-1400 condenser performance based on El-Dabaa site conditions. As the climate conditions, especially the seawater temperatures (intake for the cooling system) having a direct effects on the condenser performance and the overall NPP Efficiency, we studied the seawater temperature change based on EL-Dabaa site conditions and it's feedback on the proposed APR-1400 condenser performance and the NPP efficiency. All of the calculations and analysis had been executed by using KINGS NPA by applying EL-Dabaa seawater temperature variations for the 2 types of APR-1400 Condensers (Shinkori, south Korea and Barakah, UAE), and the main findings were as follow: For the APR-1400 condensers (Shinkori and Barakah) performance • The average difference all over the year for saturation temperature, cooling water outlet temperature, and condenser pressure are 0.135 .deg. C, .05785 .deg. C, and 0.3948 mHgA respectively. This shows that the Barakah condenser performance is not significantly better than the shinkori condenser performance based on EL-Dabaa Conditions, especially if we considered the cost difference between the two condensers designs. For APR-1400 NPPs (Shinkori and Barakah) net efficiency • The average difference all over the year for the power productions and net efficiency are 1.4791 MWe and .00037 %, respectively.

Hard rock excavation at the CSM/OCRD test site using crater theory and current United States controlled smooth wall blasting practices, June 1982

International Nuclear Information System (INIS)

Sperry, P.E.; Chitombo, G.P.; Hustrulid, W.A.

1984-08-01

This report is the fourth in a series describing experiments conducted by the Colorado School of Mines for the Office of Crystalline Repository Development (OCRD) to determine the extent of blast damage in rock surrounding an underground opening. The report describes the application of tunnel design procedures based upon crater theory and current United States controlled smooth wall blasting practices for the excavation of the CSM/OCRD test room in the Colorado School of Mines, Experimental Mine (Edgar Mine) in Idaho Springs, Colorado. Ten blast rounds were used to excavate the test room. The first seven rounds were designed with Swedish Techniques, and described in the third report in this series, and the design of rounds eight through ten used crater theory. Crater theory is described in this document along with its application to the CSM/OCRD Room excavation. Calculation for spacing, burden, number and type of holes, explosives placement, and overall powder factor are discussed. A series of single charge cratering test shots, designed to evaluate some of the input data for the blast designs, are discussed. The input data include: Strain Energy Factor E, a dimensionless factor which varies according to the explosive and rock type; Critical Depth, N, the charge depth at which the explosive begins to fracture rock at the free face; Optimum Depth Ratio Δ 0 , which is a ratio between Optimum Charge Depth, d 0 , and Critical Charge Depth, d/sub c/; and charge Weight, W. A non-linear least squared regression method to best fit the general bell-shape curve of the crater results is discussed. Both scaled weight and scaled volume criteria are reported in the analysis of results. 10 references, 17 figures, 16 tables

La cohérence dans la mobilisation du capital humain:une illustration de la théorie de l’architecture organisationnelle dans les banques de réseau

OpenAIRE

Christine Marsal

2006-01-01

(VF)S’il est courant d’opposer capital financier et capital humain les organisations mettent en place des mécanismes de coordination afin de faire converger les intérêts des deux catégories de partenaires que sont les salariés et les actionnaires. La théorie de l’architecture organisationnelle permet de fournir un cadre d’analyse pertinent pour rendre compte de ces mécanismes. Dans ce cadre nous pouvons constater la pluralité des mécanismes d’incitation. Parmi eux, les incitations financières...

Using a Classroom Response System to Improve Multiple-Choice Performance in AP[R] Physics

Science.gov (United States)

Bertrand, Peggy

2009-01-01

Participation in rigorous high school courses such as Advanced Placement (AP[R]) Physics increases the likelihood of college success, especially for students who are traditionally underserved. Tackling difficult multiple-choice exams should be part of any AP program because well-constructed multiple-choice questions, such as those on AP exams and…

Analysis of Turbine Load Rejection for APR1400 using SPACE

Energy Technology Data Exchange (ETDEWEB)

Kim, Sang Jin; Park, Chan Eok; Choi, Jong Ho; Lee, Gyu Cheon [KEPCO Engineering and Construction Co. Ltd., Deajeon (Korea, Republic of)

2016-10-15

Turbine Load Rejection event is one of the Performance Related Design Basis Event (PRDBE) that can be stabilized using plant control systems without any safety system actuation. The initiation of the event is turbine load rejection from 100% to 5% in 0.019 seconds. The NSSS control systems of APR1400 is composed of the Power Control System (PCS) and the Process-Component Control System (P-CCS). The PCS includes Reactor Regulating System (RRS), Reactor Power Cutback System (RPCS) and Digital Rod Control System (DRCS). The P-CCS includes the Pressurizer Pressure Control System (PPCS), the Pressurizer Level Control System (PLCS), the Feedwater Control System (FWCS) and the Steam Bypass Control System (SBCS). Turbine load rejection results in the increase of secondary pressure due to sudden blocking of steam flow to turbine. Then the Reactor Coolant System (RCS) cooling through steam generators is decreased rapidly and the RCS temperature will be increased. Turbine load rejection is a typical event to test NSSS control systems since it requires the automatic response of all major NSSS control systems. It is shown that the NSSS control systems of APR1400 have the capability to stabilize the plant without any safety system actuation for turbine load rejection event. This analysis results show that SPACE code has the capability to analyze the turbine load rejection event. However, further validation is necessary for other PRDBEs such as Two Main Feedwater Pumps Trip, Turbine Load Step Change and Turbine Load Ramp Down (5%/min) to verify the capability of SPACE for the full range of performance analyses.

Analysis of Turbine Load Rejection for APR1400 using SPACE

International Nuclear Information System (INIS)

Kim, Sang Jin; Park, Chan Eok; Choi, Jong Ho; Lee, Gyu Cheon

2016-01-01

Turbine Load Rejection event is one of the Performance Related Design Basis Event (PRDBE) that can be stabilized using plant control systems without any safety system actuation. The initiation of the event is turbine load rejection from 100% to 5% in 0.019 seconds. The NSSS control systems of APR1400 is composed of the Power Control System (PCS) and the Process-Component Control System (P-CCS). The PCS includes Reactor Regulating System (RRS), Reactor Power Cutback System (RPCS) and Digital Rod Control System (DRCS). The P-CCS includes the Pressurizer Pressure Control System (PPCS), the Pressurizer Level Control System (PLCS), the Feedwater Control System (FWCS) and the Steam Bypass Control System (SBCS). Turbine load rejection results in the increase of secondary pressure due to sudden blocking of steam flow to turbine. Then the Reactor Coolant System (RCS) cooling through steam generators is decreased rapidly and the RCS temperature will be increased. Turbine load rejection is a typical event to test NSSS control systems since it requires the automatic response of all major NSSS control systems. It is shown that the NSSS control systems of APR1400 have the capability to stabilize the plant without any safety system actuation for turbine load rejection event. This analysis results show that SPACE code has the capability to analyze the turbine load rejection event. However, further validation is necessary for other PRDBEs such as Two Main Feedwater Pumps Trip, Turbine Load Step Change and Turbine Load Ramp Down (5%/min) to verify the capability of SPACE for the full range of performance analyses

PLUS 7TM advanced fuel assembly development program for KSNPs and APR1400

International Nuclear Information System (INIS)

Kim, Kyutae; Stucker, David L.

2002-01-01

KNFC and Westinghouse have recently completed the development of the PLUS 7 TM advanced 16 X 16 fuel assembly for the Korean Standard Nuclear Plants (KSNPs) and the Advanced Power Reactor 1400 (APR 1400). This fuel design utilized the proven advanced design features including mixing vane spacer grids to increase critical heat flux performance, ZIRLO TM advanced materials to enable high-duty, high burnup fuel management and an optimized fuel rod diameter which improves fuel cycle cost while resulting in significant standardization of Korean fuel manufacture. PLUS 7 TM , also includes a patented spacer grid design with conformal fuel rod support designed to provide superior fuel rod wear/fretting resistance while minimizing pressure drop. This paper will present an overview of the PLUS 7 TM fuel assembly development process including a summary of the three-year design and testing program from a mechanical, neutronic, and thermal/hydraulic perspective. The PLUS 7 TM fuel for the KSNPs and the APR1400 reactors results in multi-million dollar per cycle savings in imported enriched uranium product for the Korean nuclear power program with technology specifically developed for Korea by experienced Korean engineers

A Study on the Embedment Effect in the Soil-Structure Interaction Analysis of the APR1400

International Nuclear Information System (INIS)

Young-Sun Jang; Kwang-Ho Joo; Chong-Hak Kim

2002-01-01

The SSI (Soil-Structure Interaction) analyses are being performed for the APR1400 (Advanced Power Reactor 1400 MWe, Old name - KNGR; Korean Next Generation Reactor) design, because the APR1400 is developed as a Standard Nuclear Power Plant concept enveloping suitable soil conditions. For the SSI analyses, SASSI program which adopts the Flexible Volume Method is used. In the SSI analyses, there can be uncertainties by Bond and De-bond problem between the structure and lateral soil elements. According to ASCE Standard 4, one method to address this concern is to assume no connectivity between structure and lateral soil over the upper half of the embedment of 20 ft (6 m), whichever is less. This study is performed as a part of the parametric analyses for the APR1400 seismic analyses to address the concern of the potential embedment effect on the in-structure response spectra due to connectivity between structure and lateral soil. In this study, 4 model cases are analyzed to check the potential embedment effect - Full connection, 20 ft no connectivity which is defined as a minimum De-bond depth of the soil in ASCE Standard 4 and 26.5 ft no connectivity between structure and lateral soil over the upper half of the embedment. Last one is full no connection for only reference. The in-structure response spectra are compared with the response spectra without considering the embedment effect. (authors)

Evaluation Methodology for Void Swelling Susceptibility of APR1400 Reactor Vessel Internals for U.S. NRC Design Certification

Energy Technology Data Exchange (ETDEWEB)

Kweon, Hyeong Do; Lee, Do Hwan [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

The APR1400 RVI (Reactor Vessel Internals) operates in harsh conditions, such as long term exposure to neutron irradiation, high temperatures, reactor coolant environment, and other operating loads. Therefore, even though the RVI components are mainly made of austenitic stainless steel which is well known to have good mechanical and corrosion-resistive properties, these operating conditions. The aging is characterized by a chromium depletion along grain boundaries of austenitic stainless steel, a decrease in ductility and fracture toughness of the steel, an increase in yield and ultimate strength of the steel, and a potential volume change due to void formation in the steel. For these reasons, under certain conditions of stress, temperature, and level of irradiation, the void swelling which is one of the challenging degradation mechanisms affecting the integrity of the RVI may appear at specific locations of the RVI, especially due to high neutron fluence and high temperature under localized gamma heating and low velocity of coolant flow. To assess the effects of operating neutron fluences, temperatures and stresses on the material properties changes and the susceptibility to the void swelling, the evaluation methodology of the APR1400 RVI components for U.S. NRC Design Certification was suggested in this paper. The approach to the evaluation is summarized as follows: 1. RVI component list of the APR1400 is collected. 2. Initial screening to determine the evaluation scope is completed using the design values of fluences. 3. Functionality assessments (radiation transport analysis, CFD analysis, structural analysis) are sequentially performed. 4. Susceptibility to the void swelling is identified through ANSYS/USERMAT module. KHNP believes that the proposed methodology which is based on the EPRI works for operating reactors is the best way to evaluate the void swelling for new reactors such as the APR1400.

Cloned Bacillus subtilis alkaline protease (aprA) gene showing high level of keratinolytic activity.

Science.gov (United States)

Zaghloul, T I

1998-01-01

The Bacillus subtilis alkaline protease(aprA) gene was previously cloned on a pUBHO-derivative plasmid. High levels of expression and gene stability were demonstrated when B. subtilis cells were grown on the laboratory medium 2XSG. B. subtilis cells harboring the multicopy aprA gene were grown on basal medium, supplemented with 1 % chicken feather as a source of energy, carbon, and nitrogen. Proteolytic and keratinolytic activities were monitored throughout the cultivation time. A high level of keratinolytic activity was obtained, and this indicates that alkaline protease is acting as a keratinase. Furthermore, considerable amounts of soluble proteins and free amino acids were obtained as a result of the enzymatic hydrolysis of feather. Biodegradation of feather waste using these cells represents an alternative way to improve the nutritional value of feather, since feather waste is currently utilized on a limited basis as a dietary protein supplement for animal feedstuffs. Moreover, the release of free amino acids from feather and the secreted keratinase enzyme would promote industries based on feather waste.

Constructibility assessment of APR1400

International Nuclear Information System (INIS)

Cho, Sung Jae; Kang, Yong Chul; Lee, Jae Gon; Lim, Woo Sang

2003-01-01

APR1400 (formerly KNGR) development is one of national G-7 projects sponsored by government and KHNP (Korea Hydro and Nuclear Power Co., LTD). It is an evolutionary standard reactor with the thermal output of 4000MWt and has been adopted for Shin-Kori Unit 3 and 4. The government organizations, research institutes, universities and industries have participated in the project since 1992 along with KHNP, and the standard design certification program was issued in May 2002. The project set up the top-tier requirements about the safety, economy, operability and maintainability, and constructibility in the early design stage. The requirements have been evaluated periodically during the design process, and the results were reflected to the design. This paper describes the methods for constructibility enhancement and the results of schedule analysis to assure meeting construction duration target, which is set to 48 months from the first concrete pouring to the commercial operation on the condition that learning effects are maximized at Nth plant. To meet the target schedule, the design characteristics and constructibility studies such as new construction methods and construction schedule analysis were performed. The new construction methods presented here are over the top method for NSSS components, deck plate and steel from for concrete wall and slab, automatic welding for large bore piping, and modularization of components and structure, etc. (author)

Analysis of Total Loss of Feedwater for APR1400 using SPACE

Energy Technology Data Exchange (ETDEWEB)

Hong, Seong Min; Park, Seok Jeong; Park, Chan Eok; Choi, Jong Ho; Lee, Gyu Cheon [KEPCO Engineering and Construction, Deajeon (Korea, Republic of)

2016-10-15

The Total Loss of FeedWater (TLOFW) event is an accident that main feedwater and auxiliary feedwater of secondary side are not supplied to steam generators. APR1400 uses the Safety Depressurization and Vent System (SDVS) for the F and B operation and SDVS is designed to perform the rapid depressurization function of Reactor Coolant System (RCS) through the remote manual operation when TLOFW is occurred. If RCS pressure falls below a Safety Injection Pump (SIP) working pressure, it can be possible to start the F and B operation which injects SIP flow to RCS and releases the RCS vapor and two-phase flow through Pilot Operated Safety Relief Valves (POSRVs) by opening the POSRVs, and then it can be possible to remove the decay heat. The design requirement of SDVS is that the core water level should be maintained at higher than 2 feet from the top of active core during the F and B operation. The TLOFW analysis was carried out to evaluate the capability of decay heat removal for APR1400 using newly developed SPACE code. The analysis results show that the F and B operation with 2 POSRVs and 2 SIPs and the F and B operation with 4 POSRVs and 4 SIPs meet the SDVS design requirement for the fuel cladding temperature. The comparison with RELAP5 shows good agreement and it validates the applicability of SPACE code for this type of accident analysis.

Single port-assisted fully laparoscopic abdominoperineal resection (APR) with immediate V-RAM flap reconstruction of the perineal defect.

LENUS (Irish Health Repository)

Ali, Sayid

2012-09-01

Abdominoperineal resection (APR) of anorectal cancers after neoadjuvant chemoradiotherapy may incur significant perineal morbidity. While vertical rectus abdominis muscle (V-RAM) flaps can fill the pelvic resection space with health tissue, their use has previously been described predominantly in association with laparotomy. Here, we describe a means of combination laparoscopic APR with V-RAM flap reconstruction that allows structural preservation of the entire abdominal wall throughout the oncological resection and of the deep parietal layers after V-RAM donation. Furthermore, a single port access device used at the end colostomy site allows a second senior surgeon assist with an additional two working instruments for the purpose of improved pelvic tissue retraction, especially useful in obese patients.

Diversity of sulfur-cycle prokaryotes in freshwater lake sediments investigated using aprA as the functional marker gene.

Science.gov (United States)

Watanabe, Tomohiro; Kojima, Hisaya; Takano, Yoshinori; Fukui, Manabu

2013-09-01

The diversity of sulfate-reducing prokaryotes (SRPs) and sulfur-oxidizing prokaryotes (SOPs) in freshwater lake ecosystems was investigated by cloning and sequencing of the aprA gene, which encodes for a key enzyme in dissimilatory sulfate reduction and sulfur oxidation. To understand their diversity better, the spatial distribution of aprA genes was investigated in sediments collected from six geographically distant lakes in Antarctica and Japan, including a hypersaline lake for comparison. The microbial community compositions of freshwater sediments and a hypersaline sediment showed notable differences. The clones affiliated with Desulfobacteraceae and Desulfobulbaceae were frequently detected in all freshwater lake sediments. The SOP community was mainly composed of four major phylogenetic groups. One of them formed a monophyletic cluster with a sulfur-oxidizing betaproteobacterium, Sulfuricella denitrificans, but the others were not assigned to specific genera. In addition, the AprA sequences, which were not clearly affiliated to either SRP or SOP lineages, dominated the libraries from four freshwater lake sediments. The results showed the wide distribution of some sulfur-cycle prokaryotes across geographical distances and supported the idea that metabolic flexibility is an important feature for SRP survival in low-sulfate environments. Copyright © 2013 Elsevier GmbH. All rights reserved.

Precificação de consultoria empresarial com a contribuição das estratégias de apreçamento = Entrepreneurial Counseling Pricing with Pricing Strategy Contribution

Directory of Open Access Journals (Sweden)

Nivaldo João dos Santos

2008-11-01

Full Text Available A precificação de serviços de consultoria também pode se beneficiar dos conceitos e idéias das estratégias de apreçamento de bens de consumo de massa, especificamente na área de consultoria de gestão empresarial. Apesar deste campo ser dominado por grandes corporações multinacionais, ainda existe espaço para empresas e profissionais nacionais. Por se tratar de mercado que envolve valores de grande magnitude, imaginasse que as instituições de sucesso adotem estratégia de apreçamento. Neste trabalho, estratégias de apreçamento foram selecionadas para exame e verificação de aplicabilidade quando do estabelecimento valor pelos serviços da consultoria de gestão empresarial. O apreçamento de desnatação, apreçamento de penetração, apreçamento neutro e apreçamento baseado em valor tiveram seus conceitos sintetizados para fins de verificação. O apreçamento baseado em valor se revelou o mais propício para este tipo de produto (consultoria e o processo de comunicação é o elemento crítico para evidenciar valor, benefícios e, finalmente, justificar o preço do serviço. A sugestão de roteiro para apreçamento de serviço de consultoria empresarial é apresentada ao final, como resultado da análise das diversas estratégias de apreçamento.The pricing of counseling services may also benefit from strategy concepts and ideas ofmass consumption goods pricing, specifically within the entrepreneurial managementcounseling area. Even though this field has been taken over by big multinationalcorporations, there is still some space for national enterprisings and professionals. As itis a market that involves values of great magnitude, it is thought that successfulinstitutions adopt this pricing strategy. In this study, pricing strategies were selectedfor analysis and applicability checking by the time the price for entrepreneurialmanagement counseling service was established. The skimming pricing, penetratingpricing, neutral

"A epopeia da decadência": um estudo sobre o Essai sur l'inégalité des races humaines (1853-1855, de Arthur de Gobineau

Directory of Open Access Journals (Sweden)

Helga da Cunha Gahyva

2011-12-01

Full Text Available O presente artigo discute a concepção racial de Arthur de Gobineau a partir de sua mais famosa obra, o Essai sur l'inégalité des races humaines. Se comumente este tratado é associado à discussão racialista que toma corpo nas últimas décadas do século XIX, pretendo relacioná-lo a uma polêmica característica da virada do século XVII para o XVIII, a Querela das duas raças. Neste sentido, o objetivo do artigo é revelar, em primeiro lugar, como a reflexão de Gobineau é tributária de um conceito de linhagem tornado paulatinamente anacrônico no mundo pós-revolucionário. Em segundo, demonstrar a hipótese segundo a qual o Essai, menos do que um estudo sobre raças pretensamente "biológicas", representa fundamentalmente uma recusa à nova ordem igualitária que se impõe na era moderna.The present article discusses the racial concepts of Arthur de Gobineau based on his most famous work, Essai sur l'inegalité des races humaines. Instead of associating these with the racialist debate of the last decades of the XIX the century, I relate them to a polemical text characteristic of the late XVII and early XVIII century: The Quarrel of the Two Races. In this sense, my main objective is to show that, in the first place, the Gobineau's work owes significant debts to the concept of the "bloodline", an idea which gradually became anachronistic after the French Revolution. In addition, I argue that, rather than being a study of supposedly "biological" races, Gobineau's "Essay" should be regarded as a refusal of the new egalitarian order of modern times.

Sorti d’usine

Directory of Open Access Journals (Sweden)

Robert Kosmann

2011-12-01

Full Text Available Le texte  qui suit date maintenant de  1992. Après avoir travaillé durant 18 ans à la Régie Renault, l’usine d’outillage de St Ouen (93 de ce  constructeur automobile a fermé.  J’ai alors cherché du travail, sans résultat, ne disposant à l’époque que d’un CAP de fraisage et d’un diplôme peu qualifiant de fin de collège (BEPC. Militant syndical, j’avais de plus un dossier qui ne me permettait pas d’embauche pour quelque poste que ce soit dans l’industrie si les services de ressources humain...

A Quantitative Feasibility Study on Potential Safety Improvement Effects of Advanced Safety Features in APR-1400 when Applied to OPR-1000

Energy Technology Data Exchange (ETDEWEB)

Ualikhan Zhiyenbayev [KAIST, Daejeon (Korea, Republic of); Chung, Dae Wook [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2015-10-15

This study aims to test the feasibility of the applications using Probabilistic Safety Assessment (PSA). Particularly, three of those advanced safety features are selected as follows: 1. Providing an additional Emergency Diesel Generator (EDG); 2. Increasing the capacity of Class 1E batteries; 3. Placing a Refueling Water Storage Tank (RWST) inside containment, i.e., change from RWST to IRWST. The Advanced Power Reactor 1400 (APR-1400) adopts several advanced safety features compared to its predecessor, the Optimized Power Reactor 1000 (OPR-1000), which includes an additional Emergency Diesel Generator, increase in battery capacity, in-containment refueling water storage tank (IRWST), and so on. Considering the remarkable advantages of these safety features in safety improvement and the design similarities between APR-1400 and OPR-1000, it is feasible to apply key advanced safety features of APR-1400 to OPR-1000 to enhance the safety. The selected safety features are incorporated into OPR-1000 PSA model using the Advanced Information Management System (AIMS) for PSA and CDFs are re-evaluated for each application and combination of three applications. Based on current results, it is concluded that three of key advanced safety features of APR-1400 can be effectively applied to OPR-1000, resulting in considerable safety improvement. In aggregate, three advanced safety features, which are an additional EDG, increased battery capacity and IRWST, can reduce the CDF of OPR-1000 by more than 15% when applied altogether.

A Quantitative Feasibility Study on Potential Safety Improvement Effects of Advanced Safety Features in APR-1400 when Applied to OPR-1000

International Nuclear Information System (INIS)

Ualikhan Zhiyenbayev; Chung, Dae Wook

2015-01-01

This study aims to test the feasibility of the applications using Probabilistic Safety Assessment (PSA). Particularly, three of those advanced safety features are selected as follows: 1. Providing an additional Emergency Diesel Generator (EDG); 2. Increasing the capacity of Class 1E batteries; 3. Placing a Refueling Water Storage Tank (RWST) inside containment, i.e., change from RWST to IRWST. The Advanced Power Reactor 1400 (APR-1400) adopts several advanced safety features compared to its predecessor, the Optimized Power Reactor 1000 (OPR-1000), which includes an additional Emergency Diesel Generator, increase in battery capacity, in-containment refueling water storage tank (IRWST), and so on. Considering the remarkable advantages of these safety features in safety improvement and the design similarities between APR-1400 and OPR-1000, it is feasible to apply key advanced safety features of APR-1400 to OPR-1000 to enhance the safety. The selected safety features are incorporated into OPR-1000 PSA model using the Advanced Information Management System (AIMS) for PSA and CDFs are re-evaluated for each application and combination of three applications. Based on current results, it is concluded that three of key advanced safety features of APR-1400 can be effectively applied to OPR-1000, resulting in considerable safety improvement. In aggregate, three advanced safety features, which are an additional EDG, increased battery capacity and IRWST, can reduce the CDF of OPR-1000 by more than 15% when applied altogether

Probability of Neutralization Estimation for APR1400 Physical Protection System Design Effectiveness Evaluation

Energy Technology Data Exchange (ETDEWEB)

Kim, Myungsu; Lim, Heoksoon; Na, Janghwan; Chi, Moongoo [Korea Hydro and Nuclear Power Co. Ltd. Central Research Institute, Daejeon (Korea, Republic of)

2015-05-15

It is focusing on development of a new designing process which can be compatible to international standards such as IAEA1 and NRC2 suggest. Evaluation for the design effectiveness was found as one of the areas to improve. If a design doesn't meet a certain level of effectiveness, it should be re-designed accordingly. The effectiveness can be calculated with combination of probability of Interruption and probability of neutralization. System Analysis of Vulnerability to Intrusion (SAVI) has been developed by Sandia National Laboratories for that purpose. With SNL's timely detection methodology, SAVI has been used by U.S. nuclear utilities to meet the NRC requirements for PPS design effectiveness evaluation. For the SAVI calculation, probability of neutralization is a vital input element that must be supplied. This paper describes the elements to consider for neutralization, probability estimation methodology, and the estimation for APR1400 PPS design effectiveness evaluation process. Markov chain and Monte Carlo simulation are often used for simple numerical calculation to estimate P{sub N}. The results from both methods are not always identical even for the same situation. P{sub N} values for APR1400 evaluation were calculated based on Markov chain method and modified to be applicable for guards/adversaries ratio based analysis.

Review of EU-APR Design for Selected Safety Issues of WERNA RHWG 2013

Energy Technology Data Exchange (ETDEWEB)

Kim, Yong Soo; Kim, Ji Hwan [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

Western European Nuclear Regulators' Association (WENRA) was established in 1999 to develop a harmonized approach to nuclear safety and radiation protection and their regulation. In 2013, the Reactor Harmonization Working Group (RHWG) of WENRA sets out the common positions on the seven selected key safety issues. This paper is to introduce the regulatory positions of WENRA RHWG 2013 and to review the compliance of the EU-APR with them. In this paper, we reviewed the compliance of the EUAPR regarding seven safety issues for new NPPs presented by WERNA RHWG in 2013. The EU-APR design fully complies with all WERNA RHWG safety issues since the following measures have been incorporated in it: - Successive five levels of DiD maintaining independence between different levels of DiD - Diverse design against multiple failure events such as ATWS, SBO, Loss of Ultimate Heat Sink, and Loss of Spent Fuel Pool Cooling - SAs dedicated mitigation systems to ensure the containment integrity during the SAs. - Practically eliminates accident sequences with a large or early release of radiological materials by diverse designs for multiple failure events, SAs dedicated mitigation system, and double containment design - Standard site parameters not lead to core melt accidents due to natural or man-made external hazards.

Real-time PCR quantification and diversity analysis of the functional genes aprA and dsrA of sulfate-reducing bacteria in marine sediments of the Peru continental margin and the Black Sea

Directory of Open Access Journals (Sweden)

Axel eSchippers

2011-12-01

Full Text Available A quantitative, real-time PCR (Q-PCR assay for the functional gene adenosine 5´-phosphosulfate reductase (aprA of sulfate-reducing bacteria (SRB was designed. This assay was applied together with described Q-PCR assays for dissimilatory sulfite reductase (dsrA and the 16S rRNA gene of total Bacteria to marine sediments from the Peru margin (0 – 121 meters below seafloor (mbsf and the Black Sea (0 – 6 mbsf. Clone libraries of aprA show that all isolated sequences originate from SRB showing a close relationship to aprA of characterised species or form a new cluster with only distant relation to aprA of isolated SRB. Below 40 mbsf no aprA genes could be amplified. This finding corresponds with results of the applied new Q-PCR assay for aprA. In contrast to the aprA the dsrA gene could be amplified up to sediment depths of 121 mbsf. Even in such an extreme environment a high diversity of this gene was detected. The 16S rRNA gene copy numbers of total Bacteria were much higher than those of the functional genes at all sediment depths and used to calculate the proportion of SRB to the total Bacteria. The aprA and dsrA copy numbers comprised in average 0.5 - 1 % of the 16S rRNA gene copy numbers of total Bacteria in the sediments up to a depth of ca. 40 mbsf. Depth profiles of the aprA and dsrA copy numbers were almost equal for all sites. Gene copy numbers decreased concomitantly with depth from around 108 / g sediment close to the sediment surface to less than 105 / g sediment at 5 mbsf. In the zone without detectable sulfate in the pore water from ca. 40 – 121 mbsf (Peru margin ODP site 1227, only dsrA (but not aprA was detected with copy numbers of less than 104 / g sediment, comprising ca. 14 % of the 16S rRNA gene copy numbers of total Bacteria. In this zone sulfate might be provided for SRB by anaerobic sulfide oxidation.

Developing Optimal Procedure of Emergency Outside Cooling Water Injection for APR1400 Extended SBO Scenario Using MARS Code

Energy Technology Data Exchange (ETDEWEB)

Hwang, Jong Rok; Oh, Seung Jong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2013-10-15

In this study, we examined optimum operator actions to mitigate extended SBO using MARS code. Particularly, this paper focuses on analyzing outside core cooling water injection scenario, and aimed to develop optimal extended SBO procedure. Supplying outside emergency cooling water is the key feature of flexible strategy in extended SBO situation. An optimum strategy to maintain core cooling is developed for typical extended SBO. MARS APR1400 best estimate model was used to find optimal procedure. Also RCP seal leakage effect was considered importantly. Recent Fukushima accident shows the importance of mitigation capability against extended SBO scenarios. In Korea, all nuclear power plants incorporated various measures against Fukushima-like events. For APR1400 NPP, outside connectors are installed to inject cooling water using fire trucks or portable pumps. Using these connectors, outside cooling water can be provided to reactor, steam generators (SG), containment spray system, and spent fuel pool. In U. S., similar approach is chosen to provide a diverse and flexible means to prevent fuel damage (core and SFP) in external event conditions resulting in extended loss of AC power and loss of ultimate heat sink. Hence, hardware necessary to cope with extended SBO is already available for APR1400. However, considering the complex and stressful condition encountered by operators during extended SBO, it is important to develop guidelines/procedures to best cope with the event.

Domestic activity for technical development of the APR1400's RCP performance test

Energy Technology Data Exchange (ETDEWEB)

Cho, Seok; Kim, Seok; Bae, Byung-Uhn; Cho, Yun-Jae; Kim, Yeon-Sik; Jeon, Woo-Jin; Yun, Young-Jung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2015-10-15

The thermal hydraulic and electric capability of the RCP test facility (RCPTF) covers up to 18.5 MPa, 343 .deg. C, 11.7 m{sup 3}/s, and 14.0 MW in the design pressure, temperature, flow rate, and the maximum electric power, respectively. In 2013, commissioning test had been performed to verify its designed capability, followed by several modifications in the RCPTF including signal processing and control logic to enhance verification and evaluation capability of the RCP performance. After finishing the commissioning and modification of the RCPTF, type test for the new-type RCP had been performed successfully. In this paper, several technical issues developed in the 2013 and the type test's method and results will be described. In the present paper, the technical activities for the development of the verification test of APR1400's RCP are described. KAERI has completed the full set of technology development, prerequisite for the RCP verification test, and now on the way to perform a test for the sealing capacity of the seal assembly during the Station Block Out (SBO) condition of APR1400.

Monitoring the impact of an aspartic protease (MpAPr1) on grape proteins and wine properties.

Science.gov (United States)

Theron, Louwrens Wiid; Bely, Marina; Divol, Benoit

2018-04-23

The perception of haze in wine is brought about when pathogenesis-related proteins become unstable and aggregate, subsequently resulting in crosslinking until it develops into light-dispersing particles. Elimination of these proteins is usually achieved via bentonite fining, which, although effective, suffers from several drawbacks. The utilization of proteases has been proposed as an ideal alternative. In a previous study, an aspartic protease (MpAPr1) from the yeast Metschnikowia pulcherrima was purified and shown to be partially active against grape proteins in synthetic medium. In this study, the effects of pure MpAPr1 supplemented to Sauvignon Blanc juice on subsequent fermentation were investigated. The juice was incubated for 48 h and thereafter inoculated with Saccharomyces cerevisiae. Results revealed that the enzyme had no observable effects on fermentation performance and retained activity throughout. Protein degradation could be detected and resulted in a significant modification of the wine composition and an increase in the presence of certain volatile compounds, especially those linked to amino acid metabolism.

Numerical Investigation of APR1400 Loop Seal Reformation and Clearing Phenomena during Post-LOCA Long-term Cooling Period using RELAP5

Energy Technology Data Exchange (ETDEWEB)

Lee, S. I.; Jeon, J. H.; Park, J. H.; Sung, H. J.; Lee, J. I.; Choi, T. S. [KEPCO NF, Daejeon (Korea, Republic of)

2016-10-15

Hand calculations had been tried to show that the loop seal reformation does not degrade the LTC performance of the APR1400, but the result was unclear. Therefore, the code assessments of the phenomena for APR1400 are required to guarantee the performance of LTC. In the present study, RELAP5/MOD3.3 patch04 (3.3iy) is used for the assessments. The safety degradation, e.g., possible cladding temperature rise due to LSRC during LTC period would be stronger when the safety injection (SI) is larger, while the core uncovery is more probable when the SI is smaller. In other words, it is not easy to determine the limiting condition of safety injection as two or four safety injection pumps (SIPs) in APR1400. In the present study, both the minimum SI condition with two SIPs and the maximum SI condition with four SIPs are considered. The study focuses only on the top slot break condition due to its highest possibility of LSRC phenomena. The LSRC issues for APR1400 are discussed and investigated through numerical investigation using RELAP5MOD3.3 patch04 for top-slot cold leg (pump discharge line) breaks. The major items investigated are whether the simultaneous four loop seal reformation is possible and whether there is any possible violation of the long term coolability criteria in 10 CFR 50.46. Safety injection with two SIPs and four SIPs are investigated to find that the four loop seal reformation condition before the simultaneous injection may occur only with four SIPs.

Entre guajiros et espagnols, les humains: récits Añun

Directory of Open Access Journals (Sweden)

1990-01-01

Full Text Available L’article présente une série de textes tirés de la tradition orale añun, groupe arawak en voie d’extinction (côte nord-ouest du Lac de Maracaïbo, Venezuela. Sans prendre de position théorique, l’auteur se propose de montrer comment la tradition orale, à travers des récits allégoriques évoquant les dangers de l’intégration, reflète les relations que les Añun entretiennent avec les autres groupes humains de la région et qui dans les contes, se traduisent par des métaphores animales. ENTRE GUAJIROS Y ESPAÑOLES, LOS HUMANOS - RELATOS AÑÚN. Este artículo presenta una serie de relatos de la tradición oral añún, grupo arawak en vías de extinción, localizado en el litoral noroeste del Lago de Maracaibo, Venezuela. Sin tomar ninguna posición teórica, la autora se propone mostrar a través de unos relatos alegóricos que evocan los peligros de la integración, cómo la tradición oral refleja las relaciones experimentadas por los Añún con los demás grupos humanos de la región, traducidas en los cuentos por metáforas animales. BETWEEN GUAJIROS AND SPANIARDS, THE HUMANS - AÑUN TALES. This article presents a selection of tales belonging to the oral tradition of the Añun people, an Arawak group threatened with extinction (North West coast of Maracaibo Lake, Venezuela. Leaving aside all theoretical discussion, the author attempts to show how oral tradition, through allegorical tales illustrating the dangers of integration, reflects the relationships held by the Añun with the other human groups living in the area and which, in the narrative, find expression in animal metaphors.

Apports nutritionnels, dépense et bilan énergétiques chez l’homme et les primates non-humains : aspects méthodologiques Nutritional intakes, energy expenditure and energy balance in human and non-human primates: methodological aspects

Directory of Open Access Journals (Sweden)

Laurent Tarnaud

2011-02-01

Full Text Available Cet article est une revue des méthodes de terrain et des techniques de laboratoire, traditionnelles et récentes, qui permettent d’évaluer les apports alimentaires et nutritionnels, les profils d’activité, la dépense énergétique et les réserves énergétiques corporelles des primates humains et non-humains. Cette revue a pour objectif de faire le point sur l’avancement des techniques utilisées pour estimer les paramètres énergétiques en anthropobiologie. Les primates non-humains et l’homme partagent un certain nombre de traits psycho-physiologiques issus des processus d’adaptation biologique à l’environnement et/ou liés à l’inertie phylogénétique. Identifier les mécanismes qui président à la dynamique énergétique chez les primates non-humains permet ainsi de situer certaines des bases biologiques partagées avec l’homme dans le contexte de l’évolution. Cette revue s'attache donc à présenter les méthodes en dégageant, lorsqu’ils existent, les points de recoupement des différentes approches méthodologiques appliquées à l’homme et aux primates non-humains. Par ailleurs, des comparaisons inter-populationnelles au sein de l’espèce humaine ou chez des primates non-humains permettent de préciser les relations entre les variables écologiques et les adaptations énergétiques. Dans cet article le lecteur trouvera différentes méthodes, présentées dans différents chapitres, selon qu'il s'intéresse à décrire et quantifier les apports alimentaires, nutritionnels et énergétiques des individus dans des conditions environnementales spécifiques, mesurer les dépenses énergétiques associées aux activités ou déterminer le statut nutritionnel et la composition corporelle des individus ou encore préciser le rôle des composés secondaires sur la sélection des items alimentaires et les propriétés pharmacologiques des plantes consommées. À l’origine descriptives, les méthodes actuelles

ETUDE DE L'EFFET DE QUELQUES FACTEURS SUR LA CYTOTOXICITE INDUITE PAR L'AMPHOTERICINE B ASSOCIEE AUX LIPOPROTEINES DU SERUM SANGUIN CHEZ DES CELLULES DE GLOBULES ROUGES HUMAINES

OpenAIRE

BOUCHERIT, ATMANI Zahia

2014-01-01

toxiques. Dans le cadre de l'élaboration d'une stratégie de développement de cette molécule visant à augmenter l'index thérapeutique tout en réduisant la toxicité, nous avons étudié l'effet de quelques facteurs sur la cytotoxicité induite par l'amphotéricine B associée à des lipoprotéines du sérum sanguin chez le globule rouge humain (modèle universel de cellules animales supérieures). Dans notre travail nous avons abordé d'une part, les effets des caractéristiques des lipoprot...

Post-test analysis for the APR1400 LBLOCA DVI performance test using MARS

International Nuclear Information System (INIS)

Bae, Kyoo Hwan; Lee, Y. J.; Kim, H. C.; Bae, Y. Y.; Park, J. K.; Lee, W.

2002-03-01

Post-test analyses using a multi-dimensional best-estimate analysis code, MARS, are performed for the APR1400 LBLOCA DVI (Direct Vessel Injection) performance tests. This report describes the code evaluation results for the test data of various void height tests and direct bypass tests that have been performed at MIDAS test facility. MIDAS is a scaled test facility of APR1400 with the objective of identifying multi-dimensional thermal-hydraulic phenomena in the downcomer during the reflood conditions of a large break LOCA. A modified linear scale ratio was applied in its construction and test conditions. The major thermal-hydraulic parameters such as ECC bypass fraction, steam condensation fraction, and temperature distributions in downcomer are compared and evaluated. The evaluation results of MARS code for the various test cases show that: (a) MARS code has an advanced modeling capability of well predicting major multi-dimensional thermal-hydraulic phenomena occurring in the downcomer, (b) MARS code under-predicts the steam condensation rates, which in turn causes to over-predict the ECC bypass rates. However, the trend of decrease in steam condensation rate and increase in ECC bypass rate in accordance with the increase in steam flow rate, and the calculation results of the ECC bypass rates under the EM analysis conditions generally agree with the test data

Benjamin Crémieux, Inquiétude et reconstruction. Essai sur la littérature d’après-guerre

OpenAIRE

Brangé, Mireille

2016-01-01

Après xxe siècle (1924) en 2010 reparaît ce recueil de 1931 où l’A. étudie ensemble «les faits littéraires, les concordances et les divergences qui caractérisent une époque, les formes spécifiques qu’y prennent les œuvres, […] leurs rapports avec le milieu historique et social, la vision de la vie qui s’y exprime» (p. 8). La même année que les Essais critiques d’Arland et que les articles de Drieu La Rochelle sur «la fin de l’après-guerre», il interroge l’inquiétude des années 1920 et envisag...

Migration d'une broche dans le canal médullaire cervical après une ...

African Journals Online (AJOL)

Migration d'une broche dans le canal médullaire cervical après une ostéosynthèse de l'articulation acromio-claviculaire. Bah Aliou, El Alaoui Adil. Abstract. We report the case of a 49 year-old right-handed chef with left shoulder trauma occurred during a football game. The diagnosis was fracture of the distal quarter of ...

L’Allemagne : un non – lieu pour les exiles judéo-allemands après 1945 ?

OpenAIRE

Bohnekamp, Dorothea

2017-01-01

L’omniprésence de l’Allemagne dans les productions littéraires des exilés judéo-allemands en France après 1945 pose tout d’abord la question des différentes représentations de ce pays chez les rescapés. Le nombre important de métaphores spatiales interroge plus particulièrement le rôle de l’espace, matériel/urbain ou symbolique, dans la mémoire des émigrants et dans la reconstruction d’une Heimat souvent imaginaire. Après la guerre, cet attachement souvent ambivalent à l’Allemagne comme patri...

L’amour courtois et la symbolique de la Kénose dans le motet 10 de Guillaume de Machaut

Directory of Open Access Journals (Sweden)

Charlène Mercier

2009-04-01

Full Text Available Dans l’esprit médiéval, chaque chose est ordonnée par l’harmonie de Dieu, décidée selon un plan unique. Il en va ainsi du macrocosme, de l’ordre régissant l’univers tout entier, au microcosme, allant jusqu’à gouverner la structure interne de chaque création de l’intellect humain. D’après la première épître de saint Paul aux Corinthiens (13, 12 : « Videmus nunc per speculum in aenigmate, tunc autem facie ad faciem . » Étudier une pièce de l’époque reviendrait-il à décrypter les liens cachés e...

Analysis of MSGTR events for APR1400 by means of best estimate thermal-hydraulic system code

International Nuclear Information System (INIS)

Jeong, Ji Hwan; Kim, Sang Jae; Chang, Keun Sun; Lee, Jae Hun

2001-01-01

A multiple steam generator tube rupture (MSGTR) event has never occurred in the history of commercial nuclear reactor operation while single steam generator tube rupture (SGTR) event is reported to occur every two years. As there is no history of MSGTR event, the understandings of transients and consequences of this event are not so much. In this study, a postulated MSGTR event in advanced power reactor 1400 (APR1400) is analyzed using thermal-hydraulic system code. The APR 1400 is a two-loop, 1000 MWe, PWR supposed to be built in 2009. MARS1.4 is used in this study. The present study aims to understand the effects of rupture location in heat transfer tubes and selection of affected steam generator following a MSGTR event. The effects of five tube rupture locations are compared with each other. The comparison shows that the response of APR1400 is to allow shortest time for operator action following a tubes rupture in the vicinity of hot-leg side tube sheet and to allow longest time following a tube ruptures at the tube top. The MSSV lift time for rupture at tube-top is evaluated as 24.5% larger than that for rupture at hot-leg side tube sheet. Also, the MSSV lift time for four cases are compared in order to examine how long operator response time is allowed depending on which steam generator is affected. The comparison shows that the cases for both of two steam generators are affected allow longer time for operator action compared with the cases that a single steam generator is affected. Further more, the tube ruptures in the steam generator where a pressurizer is linked leads to the shortest operator response time

La Trypanosomose Humaine Africaine dans l’espace ivoiro-burkinabé : optimisation des stratégies de surveillance épidémiologique

Directory of Open Access Journals (Sweden)

Kambiré R.

2012-11-01

Full Text Available L’objectif de cet article est de décrire les récentes données de surveillance médicale de la Trypanosomose Humaine Africaine (THA au Burkina Faso et en Côte d’Ivoire afin (i de dresser un bilan de la situation actuelle de la maladie dans ces deux pays qui entretiennent depuis plus d’un siècle des liens migratoires, économiques et épidémiologiques intimes et (ii de définir les stratégies à mettre en place dans l’objectif d’une élimination durable. Les résultats de la surveillance active et passive ont montré que les trypanosomés dépistés au Burkina-Faso ces dernières années sont tous des cas importés provenant de Côte d’Ivoire. Cependant, la réintroduction du parasite est effective et le risque d’une reprise de la transmission existe. En Côte d’Ivoire, plusieurs foyers “historiques” toujours endémiques font craindre des phénomènes de réémergence et de propagation. Dans l’objectif d’une élimination durable de la THA dans ces deux pays, les acteurs de la lutte doivent adapter leur système de surveillance en fonction des différents contextes épidémiologiques. Les prévalences actuelles ne justifient plus, excepté des cas particuliers, l’usage systématique et très onéreux du dépistage actif par prospections médicales exhaustives. Elles tendent plutôt à privilégier des systèmes intégrés aux systèmes de santé nationaux et utiliser des méthodes permettant de cibler les zones prioritaires d’intervention à partir notamment d’un échange d’informations épidémiologiques entre les deux pays. Pour accompagner le processus d’élimination durable, les acteurs de la recherche doivent étudier le rôle respectif des réservoirs humain et animal dans le maintien de la transmission, participer au suivi sur le long terme des cas traités et des suspects sérologiques, et évaluer en termes de coût/efficacité les stratégies mises en place par les Programmes Nationaux afin de les

Real-Time PCR Quantification and Diversity Analysis of the Functional Genes aprA and dsrA of Sulfate-Reducing Prokaryotes in Marine Sediments of the Peru Continental Margin and the Black Sea.

Science.gov (United States)

Blazejak, Anna; Schippers, Axel

2011-01-01

Sulfate-reducing prokaryotes (SRP) are ubiquitous and quantitatively important members in many ecosystems, especially in marine sediments. However their abundance and diversity in subsurface marine sediments is poorly understood. In this study, the abundance and diversity of the functional genes for the enzymes adenosine 5'-phosphosulfate reductase (aprA) and dissimilatory sulfite reductase (dsrA) of SRP in marine sediments of the Peru continental margin and the Black Sea were analyzed, including samples from the deep biosphere (ODP site 1227). For aprA quantification a Q-PCR assay was designed and evaluated. Depth profiles of the aprA and dsrA copy numbers were almost equal for all sites. Gene copy numbers decreased concomitantly with depth from around 10(8)/g sediment close to the sediment surface to less than 10(5)/g sediment at 5 mbsf. The 16S rRNA gene copy numbers of total bacteria were much higher than those of the functional genes at all sediment depths and used to calculate the proportion of SRP to the total Bacteria. The aprA and dsrA copy numbers comprised in average 0.5-1% of the 16S rRNA gene copy numbers of total bacteria in the sediments up to a depth of ca. 40 mbsf. In the zone without detectable sulfate in the pore water from about 40-121 mbsf (Peru margin ODP site 1227), only dsrA (but not aprA) was detected with copy numbers of less than 10(4)/g sediment, comprising ca. 14% of the 16S rRNA gene copy numbers of total bacteria. In this zone, sulfate might be provided for SRP by anaerobic sulfide oxidation. Clone libraries of aprA showed that all isolated sequences originate from SRP showing a close relationship to aprA of characterized species or form a new cluster with only distant relation to aprA of isolated SRP. For dsrA a high diversity was detected, even up to 121 m sediment depth in the deep biosphere.

Histoire d'une cité scientifique le campus du CNRS à Gif-sur-Yvette (1946-2016)

CERN Document Server

2016-01-01

L'histoire du campus de Gif-sur-Yvette, cité scientifique de renommée internationale, commence en 1946, à l'heure de la reconstruction de la recherche française, ajuste après le deuxième conflit mondial. L'histoire du campus de Gif-sur-Yvette, cité scientifique de renommée internationale, commence en 1946, à l'heure de la reconstruction de la recherche française, ajuste après le deuxième conflit mondial. À cette époque, l'on cherche à favoriser l'émergence d'études nouvelles, à soutenir les travaux fondamentaux sans s'interdire de réfléchir à leurs applications, ou encore à stimuler l'interdisciplinarité. L'acquisition du domaine par le CNRS reflète alors l'ambition de son directeur, Frédéric Joliot-Curie, de refonder la Recherche scientifique et de restaurer son rayonnement. Depuis, le campus de Gif-sur-Yvette a connu une formidable aventure, aussi bien humaine que scientifique. Pionnier dans de nombreux domaines, en biologie, en chimie mais aussi en sciences du climat et de l'env...

The Experience of Staging Nijinsky's "L'Apres-Midi d'un Faune" in a Higher Education Dance Program

Science.gov (United States)

Curran, Tina

2010-01-01

This study documented the experiences of staging Vaslav Nijinsky's "L'Apres-midi d'un Faune" in a higher education dance program. The ballet was staged from Labanotation. Research questions focused on teaching and learning pedagogy, characterization of the process over time, experiences of the participants and teaching approaches. The project…

Verification of SAMG entry condition for APR1400

Energy Technology Data Exchange (ETDEWEB)

Yun, Junghyun; Kim, Taewan; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2013-10-15

In the wake of the Fukushima accident, severe accident management has become important more than ever. While Emergency Operating Procedures (EOPs) focuses on cooling down the core during a design basis accident, the prime objective of severe accident management guideline (SAMG) is to prevent the release of radioactive material into the environment during a severe accident. Only one fixed value of core exit temperature (CET) has been applied for several decades to different types of nuclear power plants (NPPs) in Korea. Although the different types of NPPs have different cladding materials and system designs, the identical CET, i. e., 650 .deg. C, is applied as the entry condition to the SAMG of all the NPPs (except CANDU plants), i. e., Westinghouse type, OPR1000, and APR1400. In this paper, the transition point is re-evaluated for dominant severe accident sequences; station black-out (SBO), small break loss of coolant accident (SBLOCA), and me dium break loss of coolant accident (MBLOCA). In cases of SBO and SBLOCA, the current SAMG entry condition seems proper, while it needs to be reconsidered for MBLOCA case.

Analysis Of Feedwater Line Break Of APR1400 By MARS Code

International Nuclear Information System (INIS)

Nguyen Thi Thanh Thuy; Le Dai Dien, Hoang Minh Giang

2011-01-01

This paper will deal with analysis of Feed water Line Break problem (FWLB) of the APR 1400 NPP with initial conditions: operation at 100% of power, double-ended break area of 0.058 m 2 and the break location of the feedwater line between the check valve and the steam generator. The analysis was simulated by MARS code through two step: calculation for steady state and calculation for transient state with initial condition mentioned. Some output result were presented with explanation: sequence of events corresponding to the time of the accident, the system behavior as temperature, pressure, steam generator water levels as well as DNBR, etc. before and after the accident. (author)

Analysis Of Control Rod Ejection Of APR1400 By RELAP5

International Nuclear Information System (INIS)

Le Thi Thu; Hoang Minh Giang; Vo Thi Huong; Le Dai Dien

2011-01-01

This paper presents the analysis of Reactivity Induced Accident caused by ejection of a Control Element Assembly (CEA) from APR 1400 reactor vessel within 0.05 second. The initial condition were assumed as following: power level at 102%, delayed neutron fraction β = 412 pcm and CEA worth = 110 pcm. The analysis was simulated by RELAP5 code through two step: calculation of steady state and calculation of transient with initial condition mentioned as above. Some output results were presented with explanation: sequence of events corresponding to the time of the accident, the system behavior as power, reactivity feedback from fuel temperature changes (Doppler) as well as temperature, pressure, DNBR within 6 second of the accident. (author)

Nuclear wastes management: the lessons from the C.S.M. disposal site (Centre de Stockage de la Manche). Memory-less Centre, Future-less Centre?; Gestion des dechets radioactifs: les lecons du Centre de Stockage de la Manche (C.S.M.). Centre Sans Memoire, Centre Sans Avenir?

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-05-15

With its 527 217 m{sup 3} of low and medium activity wastes put in storage between 1969 and 1994, the C.S.M.( center of storage of Manche) is and remains to this day a necessary element to understand the problems posed by the eternal storage of nuclear materials and the limits of the notion of reversibility. There are therefore teachings to be drawn. We cannot repeat past mistakes in particular with high activity wastes which we wish to bury deep underground. This report is based on the analysis of the existing bibliography, of the internal A.N.D.R.A. documents which we released to the public, of the lessons drawn from our participation in the official concerting and work groups, and finally of the data obtained after inquiries were done in the region in the framework of R.I.V.I.E;R.E. (citizens network of radioecological surveillance, information and evaluation). In spite of all efforts produced, many questions remain unanswered regarding this site so it is sometimes difficult to be more precise. (N.C.)

Unit Risk Quotient (RQ) and Relative Significance of Radionuclide on Flora and Fauna to the EU-APR Optimization

Energy Technology Data Exchange (ETDEWEB)

Lee, Keunsung [KHNP-CRI, Daejeon (Korea, Republic of); Kim, Sukhoon [FNC Technology Co., Ltd., Yongin (Korea, Republic of); Lee, Chonghui [KEPCO E and C, Yongin (Korea, Republic of)

2015-05-15

As part of the project for acquiring the certification from EUR organization, in accordance with Articles 4.8 and 5.5 specified in Section 2.20 of EUR Volume 2, the effects of ionizing radiation from the standard design of EU-APR on biota and ecosystems during operation and decommissioning phases shall be assessed. This assessment must be carried out according to the ERICA (i.e. Environmental Risk from Ionizing Contaminants: Assessment and management) integrated approach. This paper describes the evaluation results for unit risk quotient and relative significance by radionuclide derived from performing Tier 1 assessment on flora and fauna for the EU-APR design using ERICA Tool. As specified previously, Pa-231 and Th-228 are the most significant for the terrestrial and for the marine/freshwater ecosystems, respectively. And, in terms of environmental risk, those radionuclides having the most impact on flora and fauna are relatively more significant than isotope having the least impact by about 7 to 10 orders of magnitude.

Unit Risk Quotient (RQ) and Relative Significance of Radionuclide on Flora and Fauna to the EU-APR Optimization

International Nuclear Information System (INIS)

Lee, Keunsung; Kim, Sukhoon; Lee, Chonghui

2015-01-01

As part of the project for acquiring the certification from EUR organization, in accordance with Articles 4.8 and 5.5 specified in Section 2.20 of EUR Volume 2, the effects of ionizing radiation from the standard design of EU-APR on biota and ecosystems during operation and decommissioning phases shall be assessed. This assessment must be carried out according to the ERICA (i.e. Environmental Risk from Ionizing Contaminants: Assessment and management) integrated approach. This paper describes the evaluation results for unit risk quotient and relative significance by radionuclide derived from performing Tier 1 assessment on flora and fauna for the EU-APR design using ERICA Tool. As specified previously, Pa-231 and Th-228 are the most significant for the terrestrial and for the marine/freshwater ecosystems, respectively. And, in terms of environmental risk, those radionuclides having the most impact on flora and fauna are relatively more significant than isotope having the least impact by about 7 to 10 orders of magnitude

CFD Analysis of Random Turbulent Flow Load in Steam Generator of APR1400 Under Normal Operation Condition

International Nuclear Information System (INIS)

Lim, Sang Gyu; You, Sung Chang; Kim, Han Gon

2011-01-01

Regulatory guide 1.20 revision 3 of the Nuclear Regulatory Committee (NRC) modifies guidance for vibration assessments of reactor internals and steam generator internals. The new guidance requires applicants to provide a preliminary analysis and evaluation of the design and performance of a facility, including the safety margins of during normal operation and transient conditions anticipated during the life of the facility. Especially, revision 3 require rigorous assessments of adverse flow effects in the steam dryer cased by flow-excited acoustic and structural resonances such as the abnormality from power-uprated BWR cases. For two nearly identical nuclear power plants, the steam system of one BWR plant experienced failure of steam dryers and the main steam system components when steam flow was increased by 16 percent for extended power uprate (EPU). The mechanisms of those failures have revealed that a small adverse flow changing from the prototype condition induced severe flow-excited acoustic and structural resonances, leading to structural failures. In accordance with the historical background, therefore, potential adverse flow effects should be evaluated rigorously for steam generator internals in both BWR and Pressurized Water Reactor (PWR). The Advanced Power Reactor 1400 (APR1400), an evolutionary light water reactor, increased the power by 7.7 percent from the design of the 'Valid Prototype', System80+. Thus, reliable evaluations of potential adverse flow effects on the steam generator of APR1400 are necessary according to the regulatory guide. This paper is part of the computational fluid dynamics (CFD) analysis results for evaluation of the adverse flow effect for the steam generator internals of APR1400, including a series of sensitivity analyses to enhance the reliability of CFD analysis and an estimation the effect of flow loads on the internals of the steam generator under normal operation conditions

JournalBase - Une étude comparative internationale des bases de données des revues scientifiques en sciences humaines et sociales (SHS

Directory of Open Access Journals (Sweden)

Christine Kosmopoulos

2009-06-01

Full Text Available Pour la première fois en 2009 ont été ici présentés dans un tableau comparatif les contenus des bases de données qui recensent les revues en sciences humaines et sociales (SHS, du Web of Science (publié par Thomson Reuters et de Scopus (publié par Elsevier ainsi que des listes de référence European Reference Index for Humanities (ERIH (publiée par la Fondation européenne pour la Science et de l'AERES. Avec quelque 20 000 entrées, c’est une vue quasi exhaustive de la richesse des publications en sciences humaines et sociales qui est enfin apportée par ce tableau. La nomenclature adoptée pour classer les revues par discipline est celle en 27 postes de la Fondation Européenne pour la Science. Les affectations multiples révèlent la multidisciplinarité des revues, assez fréquente en SHS, mais parfois aussi les incohérences des bases de données qui n’ont pas été rectifiées.La recherche a été réalisée en 2008 avec le soutien financier du TGE Adonis du CNRS.Une mise à jour prochaine sera proposée en ligne.L’objectif final de ce projet, qui concerne l'ensemble de la communauté internationale en SHS, était de mettre en ligne, en version bilingue anglais/français, la base de données de JournalBase en mode interactif sur une plate-forme collaborative ainsi que le rapport final de l’étude, afin que les décideurs, les scientifiques, les experts de l'information scientifique disposent d’informations à jour et qu’ils puissent contribuer à faire avancer la réflexion sur ces questions, par l’échange d’expériences et de bonnes pratiques d’utilisation.Un article présentant l'historique du projet, la méthodologie mise en place et les difficultés rencontrées dans la comparaison des données a été publié le 8 janvier 2010. Il analyse également les premiers résultats.Désormais vous pouvez accéder à l'information intégrale de JournalBase sur le site : http://journalbase.cnrs.fr

Mitas kaip kultūrų interpretacijų sankirta Cliffordo Geertzo antropologijoje | Le mythe comme un ensemble des interprétations des cultures dans l‘antropologie de Clifford Geertz

Directory of Open Access Journals (Sweden)

Neringa Mikalauskienė

2007-01-01

Full Text Available La méthode que Clifford Geertz appelle, lui-même, «une description dense» [thick description] peut être nommée une interprétation inductive parce qu’ici on passe de différentes formes de la culture aux conclusions générales: on commence par une analyse minutieuse («microscopique» des moindres phénomènes et on finit par des interprétations et des définitions plus globales. Le mythe se trouve introduit dans «les moindres phénomènes» et, en même temps, il apparaît comme agissant dans les différentes sphères de la vie. Le mythe «s’eparpille» tant dans le langage quotidien, tant dans les normes réglant la vie sociale que dans la religion.Pour Geertz le mythe est un système de symboles qui forme des motivations constantes de la conduite humaine. Ce système révèle une conception d’être qui se manifeste dans le quotidien de la sorte que les motivations de la conduite se montrent réellement. L’analyse du mythe, d’après Geertz, est inséparable du celle du rite qui fait, à son tour, partie du drame rituel où la distance entre le spectateur et l’acteur est abolie. La nature humaine, entraînée dans la magie du théâtre rituel, se voit transformée, et les êtres humains sont ainsi inscrits dans la société.Le mythe est un fait culturel concret et il peut surgir dans de différents domaines de la vie. Il est possible donc de le traiter comme un moyen d’approche de toute la culture parce que celle-ci n’est qu’une totalité des systèmes convergents de significations: de la religion, de l’art, de l’idéologie, du droit ect.Le mythe est lu, tout d’abord, comme un texte spécifique utile à l’analyse de la culture parce qu’il est un dépôt de symboles constants. Et la culture, d’après Geertz, effectue un contrôle symbolique de la conduite.L’analyse du mythe est une fiction an premier sens du mot fictio: «modelé», «fait». Cette analyse n’est rien d’autre qu’une prévision des

Preliminary design of S-CO{sub 2} Brayton cycle for APR-1400 with power generation and desalination process

Energy Technology Data Exchange (ETDEWEB)

Bae, Seong Jun; Lee, Won Woong; Jeong, Yong Hoon; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of); Yoon, Ho Joon [KUSTAR, Abu Dhabi (United Arab Emirates)

2015-10-15

This study was conducted to explore the capabilities of the S-CO{sub 2} Brayton cycle for a cogeneration system for APR-1400 application. Three concepts of the S-CO{sub 2} simple recuperated co-generation cycle were designed. A supercritical CO{sub 2} (S-CO{sub 2}) Brayton cycle is recently receiving significant attention as a promising power conversion system in wide range of energy applications due to its high efficiency and compact footprint. The main reason why the S-CO{sub 2} Brayton cycle has these advantages is that the compressor operates near the critical point of CO{sub 2} (30.98 .deg. C, 7.38MPa) to reduce the compression work significantly compared to the other Brayton cycles. In this study, the concept of replacing the entire steam cycle of APR-1400 with the S-CO{sub 2} Brayton cycle is evaluated. The power generation purpose S-CO{sub 2} Brayton cycles are redesigned to generate power and provide heat to the desalination system at the same time. The performance of these newly suggested cycles are evaluated in this paper. The target was to deliver 147MW heat to the desalination process. The thermal efficiencies of the three concepts are not significantly different, but the 3{sup rd} concept is relatively simpler than other cycles because only an additional heat exchanger is required. Although the 2{sup nd} concept is relatively complicated in comparison to other concepts, the temperatures at the inlet and outlet of the DHX are higher than that of the others. As shown in the results, the S-CO{sub 2} Brayton cycles are not easy to outperform the steam cycle with very simple layout and general design points under APR-1400 operating condition. However, this study shows that the S-CO{sub 2} Brayton cycles can be designed as a co-generation cycle while producing the target desalination heat with a simple configuration. In addition, it was also found that the S-CO{sub 2} Brayton cycle can achieve higher cycle thermal efficiency than the steam power cycle under

EFFET DES VITAMINES B12, B9 ET B6 ET LEURS INTERACTIONS SUR LA FRAGILITE OSMOTIQUE DES ERYTHROCYTES HUMAINS

Directory of Open Access Journals (Sweden)

B HOUCHER

2001-06-01

Full Text Available L’effet des vitamines B12, B9 et B6 sur la fragilité osmotique des érythrocytes humains a été exploré in vitro. De fortes concentrations de vitamines B12 et B6 ont protégé les érythrocytes de l’hémolyse hypotonique, avec une protection maxima atteinte respectivement à 10 et 500 µg/ml. A concentrations plus faibles, cependant, ces vitamines ont favorisé grandement l’hémolyse hypotonique. Par contre, la vitamine B9 a montré uniquement un effet hémolytique de 4 à 200 µg/ml. Cet effet peut être expliqué par la nature acide de la molécule. L’effet nul sur la fragilité osmotique de deux vitamines antagonistes, peut probablement être expliqué par l’antagonisme partiel ou par la présence de ces deux vitamines simultanément: ces dernières se lient en quantités appréciables à la cellule intacte de même qu’à l’hémolysat et il y’ a compétition mutuelle entre ces vitamines et leur transport.

Best-estimated multi-dimensional calculation during LB LOCA for APR1400

International Nuclear Information System (INIS)

Oh, D. Y.; Bang, Y. S.; Cheong, A. J.; Woong, S.; Korea, W.

2010-01-01

Best-estimated (BE) calculation with uncertainty quantification for the emergency core cooling system (ECCS) performance analysis during Loss of Coolant Accident (LOCA) is more broadly used in nuclear industries and regulations. In Korea, demand on regulatory audit calculation is continuously increasing to support the safety review for life extension, power up-rating and advanced nuclear reactor design. The thermal-hydraulic system code, MARS (Multi-dimensional Analysis of Reactor Safety), with multi-dimensional capability is used for audit calculation. It achieves to describe the complicated phenomena in reactor coolant system by very effectively consolidating the one dimensional RELAP5/MOD3 with the multidimensional COBRA-TF codes. The advanced power reactors (APR1400) to be evaluated has four separated hydraulic trains of the high pressure injection system (HPSI) with direct vessel injection (DVI) which is different from the existing commercial PWRs. Also, the therma-hydraulic behavior of DVI plant would be considerably different from that of a cold-leg safety injection since the low pressure safety injection system are eliminated and the high pressure safety flow are injected into the specific elevation of reactor vessel downcomer. The ECCS bypass induced by the downcomer boiling due to hot wall heating of reactor vessel during reflooding phase is one of the important phenomena which should be considered in DVI plants. Therefore, in this study, BE calculation with one-dimensional (1-D) and multi-dimensional (multi-D) MARS models during LBLOCA are performed for APR1400 plant. In the multi-D evaluation, the reactor vessel is modeled by multi-D components and the specific treatment of flow path inside reactor vessel, e.g., upper guide structure, is essential. The concept of hot zone is adopted to simulate the limiting thermal-hydraulic conditions surrounding hot rod, which is similar to hot channel in 1-D. Also, alternative treatment of the hot rods in multi-D is

Recovery and radio-resistance in mice after external irradiation; Restauration et radio-resistance chez la souris apres irradiation externe

Energy Technology Data Exchange (ETDEWEB)

Le Guillou, S [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1965-07-01

The author presents a literature study concerning recovery from external irradiation and an analysis of experimental data (which appear to suggest the idea of a radio-resistance in animals), as well as the hypotheses put forward for explaining this phenomenon. The author then describes an experiment carried out on mice whose LD 50/30 days increased from 1005 to 1380 rads and for which it was shown that an increase occurs in the number of certain anti-bodies circulating after a low dose of {gamma} irradiation. (author) [French] L'auteur presente une etude bibliographique de la restauration apres irradiation externe et une analyse des donnees experimentales qui paraissent suggerer la notion de radioresistance chez les animaux ainsi que les hypotheses cherchant a expliquer ce phenomene. Il relate ensuite une experience realisee sur des souris dont la DL 50/30 jours est passee de 1005 a 1380 rads et dans laquelle est montree l'augmentation de certains anticorps circulant apres une faible dose d'irradiation gamma. (auteur)

A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts

Directory of Open Access Journals (Sweden)

Liang Y

2018-03-01

Full Text Available Yayun Liang,1 Benford Mafuvadze,1 Cynthia Besch-Williford,2 Salman M Hyder1 1Deparment of Biomedical Sciences and Dalton Cardiovascular Research Center, Columbia, MO, USA; 2IDEXX BioResearch, Columbia, MO, USA Background: Between 30 and 40% of human breast cancers express a defective tumor suppressor p53 gene. Wild-type p53 tumor suppressor protein promotes cell-cycle arrest and apoptosis and inhibits vascular endothelial growth factor–dependent angiogenesis, whereas mutant p53 protein (mtp53 lacks these functions, resulting in tumor cell survival and metastasis. Restoration of p53 function is therefore a promising drug-targeted strategy for combating mtp53-expressing breast cancer. Methods: In this study, we sought to determine whether administration of APR-246, a small-molecule drug that restores p53 function, in combination with 2aG4, an antibody that targets phosphatidylserine residues on tumor blood vessels and disrupts tumor vasculature, effectively inhibits advanced hormone-dependent breast cancer tumor growth. Results: APR-246 reduced cell viability in mtp53-expressing BT-474 and T47-D human breast cancer cells in vitro, and significantly induced apoptosis in a dose-dependent manner. However, APR-246 did not reduce cell viability in MCF-7 breast cancer cells, which express wild-type p53. We next examined APR-246’s anti-tumor effects in vivo using BT-474 and T47-D tumor xenografts established in female nude mice. Tumor-bearing mice were treated with APR-246 and/or 2aG4 and tumor volume followed over time. Tumor growth was more effectively suppressed by combination treatment than by either agent alone, and combination therapy completely eradicated some tumors. Immunohistochemistry analysis of tumor tissue sections demonstrated that combination therapy more effectively induced apoptosis and reduced cell proliferation in tumor xenografts than either agent alone. Importantly, combination therapy dramatically reduced the density of blood

Comparison of APR1400 safety between brake site and shin-Kori site Due to the difference in the climate conditions

International Nuclear Information System (INIS)

Yoon, Ho Joon; Lee, Jeong Ik; Lee, Jeong Ik

2012-01-01

Brake Nuclear Power Plant (BNPP) is now under the construction based on APR1400 designed by Korean Electric Power Corporation (KEPCO). APR1400 is a two loop pressurized water reactor, the nuclear steam supply system (NSSS) US designed for about put of 4,000 MWt, with a corresponding electrical output of approximately 1,390 MWe. The first APR1400 (SKN 3 and 4) constructed in Shin-Kori, Korea has been modified according to the surrounding environment of the United Arab Emirates. In this paper, authors would like to compare safety issues between B NPP and Skin due to the changes of surroundings, since the site characteristics are very different. For instance, the mean annual air temperature in the UAE is 28 .deg. C and the peak air temperature was recorded as 48.8 .deg. C. Sea temperatures are varying from 17. deg. C in January to 35. deg. C in August, while that of Korea is in 9-16. deg. C range. Hot climate of UAE and the malfunction of HVAC system can lead the increasing of the water temperature in safety injection system (SIS). The heated water in SIS may affect the safety margin of the peak cladding temperature (PCT). The change of PCT and response time according to design basis accident scenarios such as large break LOCA are analyzed in detail. To evaluate such effect, Mars code was utilized to evaluate assumed condition by KAIST and the analyses of the results were carried out by Khalifa Univ.

Réduction des pertes de mangues après la récolte en Asie du Sud ...

International Development Research Centre (IDRC) Digital Library (Canada)

29 avr. 2016 ... Près de 70 % de la production mondiale de mangues provient de l'Inde, mais les pertes après récolte en raison d'une manutention, d'un transport et d'une transformation inadéquats peuvent atteindre 35 %. De plus, les prix obtenus par les producteurs sont souvent peu élevés à cause de la saturation du ...

Le don après un décès d'origine cardiocirculatoire au Canada

Science.gov (United States)

Shemie, Sam D.; Baker, Andrew J.; Knoll, Greg; Wall, William; Rocker, Graeme; Howes, Daniel; Davidson, Janet; Pagliarello, Joe; Chambers-Evans, Jane; Cockfield, Sandra; Farrell, Catherine; Glannon, Walter; Gourlay, William; Grant, David; Langevin, Stéphan; Wheelock, Brian; Young, Kimberly; Dossetor, John

2006-01-01

Résumé Ces recommandations sont le fruit d'un processus multidisciplinaire national ayant duré un an et visant à déterminer si et comment l'on pourrait procéder au don d'organes après un décès d'origine cardiocirculatoire («don après le décès cardiocirculatoire», ou DDC) au Canada. Le forum national organisé en février 2005 a permis aux participants de discuter et d'élaborer des recommandations sur les principes, interventions et pratiques se rapportant au DDC. Les aspects éthiques et juridiques ont été abordés dans les discussions. À la fin du Forum, la majorité des participants ont été favorables à l'implantation de programmes de DDC au Canada. Les participants du Forum ont également convenu qu'il fallait formuler et prôner des valeurs fondamentales pour orienter l'élaboration de programmes et de protocoles basés sur le cadre médical, éthique et juridique établi lors de cette réunion. Même si la possibilité d'un don d'organes et de tissus doit faire partie intégrante des soins de fin de vie, il faut insister sur le fait que le devoir de diligence envers les patients mourants et leurs familles doit demeurer la priorité des équipes soignantes. La complexité et les répercussions profondes du décès sont reconnues et doivent être respectées, de même que les différences personnelles, ethnoculturelles et religieuses face à la mort et au don d'organes. Les décisions d'arrêter le traitement de maintien des fonctions vitales, la prise en charge des derniers moments de la vie et le diagnostic de décès selon des critères cardiocirculatoires doivent être distincts et indépendants des processus de don et transplantation. Ce rapport contient des recommandations destinées aux gestionnaires de program, aux autorités sanitaires régionales et aux instances appelés à élaborer les protocoles de DDC. Les programmes doivent être conçus en fonction des éléments suivants : direction et planification locales, éducation et

Preliminary Analysis of Ex-Vessel Steam Explosion using TEXAS-V code for APR1400

International Nuclear Information System (INIS)

Song, Sung Chu; Lee, Jung Jae; Cho, Yong Jin; Hwang, Taesuk

2013-01-01

The purpose of this study is to explore input development and the audit calculation using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS computational models are one of the simplified tools for simulations of fuel-coolant interaction during mixing, triggering and explosion phase. The models of TEXAS code were validated by performing the fundamental experimental investigation in the KROTOS facility at JRC, Ispra. The experiments such as KROTOS and FARO experiment are aimed at providing benchmark data to examine the effect of fuel-coolant initial conditions and mixing on explosion energetics with alumina and prototypical core material. TEXAS-V code used in this study was to analyze and predict the ex-vessel steam explosion for a reactor scale. The input deck to simulate the flooded reactor cavity of APR1400 is developed and base case calculation is performed. This study will provide a base for further study. The code will be of use for the evaluation and sensitivity study of ex-vessel steam explosion for ERVC strategy in the future studies. Analysis result of this study is similar to the result of other study. Through this study, it is found that TEXAS-V could be the used as a tool for predicting the steam explosion load on a reactor scale, as fast running computer code. In addition, TEXAS-V code could be to evaluate the impact of various uncertainties, which are not clearly understood yet, to provide a conservative envelope for the steam explosion

Preliminary Analysis of Ex-Vessel Steam Explosion using TEXAS-V code for APR1400

Energy Technology Data Exchange (ETDEWEB)

Song, Sung Chu; Lee, Jung Jae; Cho, Yong Jin; Hwang, Taesuk [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2013-10-15

The purpose of this study is to explore input development and the audit calculation using TEXAS-V code for ex-vessel steam explosion for a flooded reactor cavity of APR1400. TEXAS computational models are one of the simplified tools for simulations of fuel-coolant interaction during mixing, triggering and explosion phase. The models of TEXAS code were validated by performing the fundamental experimental investigation in the KROTOS facility at JRC, Ispra. The experiments such as KROTOS and FARO experiment are aimed at providing benchmark data to examine the effect of fuel-coolant initial conditions and mixing on explosion energetics with alumina and prototypical core material. TEXAS-V code used in this study was to analyze and predict the ex-vessel steam explosion for a reactor scale. The input deck to simulate the flooded reactor cavity of APR1400 is developed and base case calculation is performed. This study will provide a base for further study. The code will be of use for the evaluation and sensitivity study of ex-vessel steam explosion for ERVC strategy in the future studies. Analysis result of this study is similar to the result of other study. Through this study, it is found that TEXAS-V could be the used as a tool for predicting the steam explosion load on a reactor scale, as fast running computer code. In addition, TEXAS-V code could be to evaluate the impact of various uncertainties, which are not clearly understood yet, to provide a conservative envelope for the steam explosion.

Reliability analysis of protection system of advanced pressurized water reactor - APR 1400

International Nuclear Information System (INIS)

Varde, P. V.; Choi, J. G.; Lee, D. Y.; Han, J. B.

2003-04-01

Reliability analysis was carried out for the protection system of the Korean Advanced Pressurized Water Reactor - APR 1400. The main focus of this study was the reliability analysis of digital protection system, however, towards giving an integrated statement of complete protection reliability an attempt has been made to include the shutdown devices and other related aspects based on the information available to date. The sensitivity analysis has been carried out for the critical components / functions in the system. Other aspects like importance analysis and human error reliability for the critical human actions form part of this work. The framework provided by this study and the results obtained shows that this analysis has potential to be utilized as part of risk informed approach for future design / regulatory applications

Multi-pentad prediction of precipitation variability over Southeast Asia during boreal summer using BCC_CSM1.2

Science.gov (United States)

Li, Chengcheng; Ren, Hong-Li; Zhou, Fang; Li, Shuanglin; Fu, Joshua-Xiouhua; Li, Guoping

2018-06-01

Precipitation is highly variable in space and discontinuous in time, which makes it challenging for models to predict on subseasonal scales (10-30 days). We analyze multi-pentad predictions from the Beijing Climate Center Climate System Model version 1.2 (BCC_CSM1.2), which are based on hindcasts from 1997 to 2014. The analysis focus on the skill of the model to predict precipitation variability over Southeast Asia from May to September, as well as its connections with intraseasonal oscillation (ISO). The effective precipitation prediction length is about two pentads (10 days), during which the skill measured by anomaly correlation is greater than 0.1. In order to further evaluate the performance of the precipitation prediction, the diagnosis results of the skills of two related circulation fields show that the prediction skills for the circulation fields exceed that of precipitation. Moreover, the prediction skills tend to be higher when the amplitude of ISO is large, especially for a boreal summer intraseasonal oscillation. The skills associated with phases 2 and 5 are higher, but that of phase 3 is relatively lower. Even so, different initial phases reflect the same spatial characteristics, which shows higher skill of precipitation prediction in the northwest Pacific Ocean. Finally, filter analysis is used on the prediction skills of total and subseasonal anomalies. The results of the two anomaly sets are comparable during the first two lead pentads, but thereafter the skill of the total anomalies is significantly higher than that of the subseasonal anomalies. This paper should help advance research in subseasonal precipitation prediction.

Analysis of a 12-Finger Rod Drop using RETRAN/MASTER Code System for APR1400

International Nuclear Information System (INIS)

Yu, Keuk Jong; You, Sung Chang; Kim, Han Gon

2009-01-01

The Optimized Power Reactor 1000 (OPR1000) has 4-finger and 12-finger Control Element Assemblies (CEAs). When the 12-finger CEA is dropped, Core Protection Calculator System (CPCS) shuts down the reactor to prevent fuel damage that could occur from the sudden reactor power peaking. By contrast, the improved CPCS of Advanced Power Reactor 1400 (APR1400), which has systems similar to those of the OPR1000, decreases reactor power rapidly using its Reactor Power Cutback System (RPCS) to avoid unwanted reactor trips caused by the CPCS during a 12- finger CEA drop event. RETRAN is a best-estimate code for transient analysis of Non-LOCA. The RETRAN control logic, which includes the function of reducing reactor power during a 12-Finger CEA drop, has been developed for the APR1400. A MATRAN program has also been developed. MATRAN is the interface program for realtime processing to connect RETRAN with MASTER code which is a nuclear analysis and design code. MATRAN supplies adequate feedback reactivities from the MASTER code to RETRAN code. The purpose of this study is to analyze the behavior of a nuclear reactor core and its primary system using conventional RETRAN analysis procedure and MATRAN program analysis procedure during a 12- finger CEA drop. In addition, the axial power distribution and Axial Shape Index (ASI) are produced by the MATRAN program and they are confirmed as within operation limits

Recovery and radio-resistance in mice after external irradiation; Restauration et radio-resistance chez la souris apres irradiation externe

Energy Technology Data Exchange (ETDEWEB)

Le Guillou, S. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1965-07-01

The author presents a literature study concerning recovery from external irradiation and an analysis of experimental data (which appear to suggest the idea of a radio-resistance in animals), as well as the hypotheses put forward for explaining this phenomenon. The author then describes an experiment carried out on mice whose LD 50/30 days increased from 1005 to 1380 rads and for which it was shown that an increase occurs in the number of certain anti-bodies circulating after a low dose of {gamma} irradiation. (author) [French] L'auteur presente une etude bibliographique de la restauration apres irradiation externe et une analyse des donnees experimentales qui paraissent suggerer la notion de radioresistance chez les animaux ainsi que les hypotheses cherchant a expliquer ce phenomene. Il relate ensuite une experience realisee sur des souris dont la DL 50/30 jours est passee de 1005 a 1380 rads et dans laquelle est montree l'augmentation de certains anticorps circulant apres une faible dose d'irradiation gamma. (auteur)

The Analysis of Uncontrolled CEA Bank withdrawal from low power Accident for APR1400 Using KNAP

International Nuclear Information System (INIS)

Yang, Chang-Keun; Kim, Yo-Han; Ha, Sang-Jun

2006-01-01

In Korea, the nuclear industries such as fuel manufacturer, the architect engineer and the utility, have been using the methodologies and codes of vendors, such as Westinghouse(WH), Combustion Engineering(CE), for the safety analyses of nuclear power plants. Consequently the industries have kept up the many organizations to operate the methodologies and to maintain the codes for each vendor. It may cause difficulty to improve the safety analyses efficiency and technology related. So, the necessity another of methodologies and code systems applicable to Non- LOCA, beyond design basis accident and performance analyses for all types of pressurized water reactor (PWR) has been raised. As the first requirement, the best-estimate codes were required for applicable wider application area and realistic behavior prediction of power plants with various and sophisticated functions. After the review on several candidates, RETRAN-3D has been chosen as a system analysis code. The draft version of the methodology was developed based on the references for the general purpose, and modified to apply it to specific plants in Korea. As a part of the feasibility estimation for the methodology and code system, uncontrolled CEA bank withdrawal from low power accident for the Advanced Power Reactor 1400(APR1400) was selected to verify the feasibility using the RETRAN-3D. And the results were compared with the Standard Safety Analysis Reports (SSAR) of APR1400

Performance Assessment of Turbulence Models for the Prediction of the Reactor Internal Flow in the Scale-down APR+

International Nuclear Information System (INIS)

Lee, Gonghee; Bang, Youngseok; Woo, Swengwoong; Kim, Dohyeong; Kang, Minku

2013-01-01

The types of errors in CFD simulation can be divided into the two main categories: numerical errors and model errors. Turbulence model is one of the important sources for model errors. In this study, in order to assess the prediction performance of Reynolds-averaged Navier-Stokes (RANS)-based two equations turbulence models for the analysis of flow distribution inside a 1/5 scale-down APR+, the simulation was conducted with the commercial CFD software, ANSYS CFX V. 14. In this study, in order to assess the prediction performance of turbulence models for the analysis of flow distribution inside a 1/5 scale-down APR+, the simulation was conducted with the commercial CFD software, ANSYS CFX V. 14. Both standard k-ε model and SST model predicted the similar flow pattern inside reactor. Therefore it was concluded that the prediction performance of both turbulence models was nearly same. Complex thermal-hydraulic characteristics exist inside reactor because the reactor internals consist of fuel assembly, control rod assembly, and the internal structures. Either flow distribution test for the scale-down reactor model or computational fluid dynamics (CFD) simulation have been conducted to understand these complex thermal-hydraulic features inside reactor

Réduction des pertes de mangues après la récolte en Asie du Sud ...

International Development Research Centre (IDRC) Digital Library (Canada)

29 avr. 2016 ... On a également conçu des boîtes spéciales contenant de la fibre de banane imprégnée d'hexanal, dont l'utilisation pour le transport de la mangue permet de conserver le fruit beaucoup plus longtemps. Réduction des pertes de mangues après la récolte en Asie du Sud​ (PDF, 506 Ko). Il s'agit de l'une ...

Minimum containment pressure and its effect on ECCS performance of APR-1400

International Nuclear Information System (INIS)

Kim, In Goo; Bang, Young S.; Kim, Hho Jung

2004-01-01

The containment pressure has a strong effect on the late reheat behavior for a large break LOCA, associated with the DVI issue. The downcomer boiling, which occurs during the post-reflood phase, has a negative effect on core cooling for a LBLOCA. Because the downcomer boiling is enhanced as the containment pressure decreases, how to determine containment pressure is important to the evaluation of ECCS performance. In spite of its importance of containment pressure, there are few studies on the containment pressure and the interaction between RCS and containment thermal hydraulics. To have a better knowledge of the effect of containment pressure on APR-1400 ECCS performance, a parametric study for containment pressure has been carried out. Also, the interaction between RCS and containment behavior has been also investigated

A la recherche de la dimension sociale du développement durable

Directory of Open Access Journals (Sweden)

Christian Brodhag

2004-03-01

Full Text Available Au sens le plus large, le développement soutenable vise à favoriser un état d’harmonie entre les êtres humains et entre l’homme et la nature (CMED, 1988. Mais si les études portant sur les rapports entre l’homme et la nature s’accumulent, celles portant sur l’harmonie entre êtres humains trouvent encore assez peu d’échos. A l’échelle territoriale, comment faire valoir cette harmonie sociale ? Après quelques rappels théoriques sur les notions de développement durable, de négociation et conservation, la dernière partie est consacrée à la présentation de l’acteur en 4 dimensions (4D, une proposition méthodologique qui vise à faciliter une démarche de gestion à la fois intégrée et participative des ressources naturelles.In a broader sense, sustainable development aims to enhance a state of harmony between human beings and between man and nature (CMED, 1988. Yes, but if studies on man and nature relationships are frequently conducted, those on harmony between human beings remain pretty rare. On a territory, how can we value this social harmony ? After a few recall of the notions of sustainable development, negotiation and conservation, the last part will present the Actor in 4 dimensions, a methodological proposition which aims to facilitate integrated and participatory management approaches toward natural resources.

Use case driven approach to develop simulation model for PCS of APR1400 simulator

International Nuclear Information System (INIS)

Dong Wook, Kim; Hong Soo, Kim; Hyeon Tae, Kang; Byung Hwan, Bae

2006-01-01

The full-scope simulator is being developed to evaluate specific design feature and to support the iterative design and validation in the Man-Machine Interface System (MMIS) design of Advanced Power Reactor (APR) 1400. The simulator consists of process model, control logic model, and MMI for the APR1400 as well as the Power Control System (PCS). In this paper, a use case driven approach is proposed to develop a simulation model for PCS. In this approach, a system is considered from the point of view of its users. User's view of the system is based on interactions with the system and the resultant responses. In use case driven approach, we initially consider the system as a black box and look at its interactions with the users. From these interactions, use cases of the system are identified. Then the system is modeled using these use cases as functions. Lower levels expand the functionalities of each of these use cases. Hence, starting from the topmost level view of the system, we proceeded down to the lowest level (the internal view of the system). The model of the system thus developed is use case driven. This paper will introduce the functionality of the PCS simulation model, including a requirement analysis based on use case and the validation result of development of PCS model. The PCS simulation model using use case will be first used during the full-scope simulator development for nuclear power plant and will be supplied to Shin-Kori 3 and 4 plant. The use case based simulation model development can be useful for the design and implementation of simulation models. (authors)

Multi-analytical characterisation of D’Aprés Cormon by José Veloso Salgado

Energy Technology Data Exchange (ETDEWEB)

Cardeira, A.M. [Faculdade de Belas-Artes da Universidade de Lisboa, Largo da Academia Nacional de Belas-Artes, 1249-058 Lisboa (Portugal); Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Longelin, S. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Costa, S.; Candeias, A. [Laboratório José de Figueiredo, Direcção Geral do Património Cultural, Rua das Janelas Verdes 37, 1249-018 Lisboa (Portugal); Laboratório HERCULES e Centro de Química de Évora, Universidade de Évora, Largo Marquês de Marialva 8, 7000 Évora (Portugal); Carvalho, M.L. [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal); Manso, M., E-mail: marta974@cii.fc.ul.pt [Centro de Física Atómica da Universidade de Lisboa, Av. Professor Gama Pinto 2, 1649-003 Lisboa (Portugal)

2014-07-15

This case study reveals the analytical characterisation carried out on ‘D’Aprés Cormon’ (1891) by Veloso Salgado, a copy of ‘Caïn’ (1880) by Fernando Cormon, belonging nowadays to Musée d’Orsay. Infrared Reflectography made in situ revealed underdrawing grid that was used to transpose the original painting to a smaller scale, pictorial style, execution method and retouched/restored areas. In situ EDXRF analysis together with Raman microscopy allowed the identification of gypsum, lead white, titanium white, yellow ochre, vermilion, ultramarine and lamp black. These results provide valuable information about the Salgado’s palette and his production technique.

Nuclear wastes management: the lessons from the C.S.M. disposal site (Centre de Stockage de la Manche. Memory-less Centre, Future-less Centre?

International Nuclear Information System (INIS)

2006-05-01

With its 527 217 m 3 of low and medium activity wastes put in storage between 1969 and 1994, the C.S.M.( center of storage of Manche) is and remains to this day a necessary element to understand the problems posed by the eternal storage of nuclear materials and the limits of the notion of reversibility. There are therefore teachings to be drawn. We cannot repeat past mistakes in particular with high activity wastes which we wish to bury deep underground. This report is based on the analysis of the existing bibliography, of the internal A.N.D.R.A. documents which we released to the public, of the lessons drawn from our participation in the official concerting and work groups, and finally of the data obtained after inquiries were done in the region in the framework of R.I.V.I.E;R.E. (citizens network of radioecological surveillance, information and evaluation). In spite of all efforts produced, many questions remain unanswered regarding this site so it is sometimes difficult to be more precise. (N.C.)

Appraisal of the Psychiatric Diagnostic Screening Questionnaire in a perinatal cohort: The APrON study.

Science.gov (United States)

Leung, Brenda; Letourneau, Nicole; Bright, Katherine; Giesbrecht, Gerald F; Ntanda, Henry; Gagnon, Lisa

2017-08-01

Depression and anxiety are routinely screened as part of perinatal care. However, other Axis 1 disorders and specific anxiety disorders are less likely to be screened or assessed as part of obstetric care. The objective of this study was to determine whether the Psychiatric Diagnostic Screening Questionnaire (PDSQ) is a potentially useful tool to screen for psychiatric conditions in pregnant and postpartum women in a community setting. We compared the prevalence of DSM Axis I disorders obtained on the PDSQ with: (1) the prevalence of these disorders reported in previous studies of pregnant and postpartum women, and (2) scores obtained on the Edinburgh Postpartum Depression Scale (EPDS) and the Symptom Checklist-90-Revised (SCL-90R) anxiety scale. Data were obtained from the Alberta Pregnancy Outcomes and Nutrition (APrON) study. The PDSQ was completed by 1575 women prenatally and 1481 postnatally. The three most prevalent PDSQ conditions were social phobia, somatic disorder, and obsessive-compulsive disorder (OCD). The prevalence of social phobia, alcohol disorder, OCD and psychosis were higher in the APrON cohort compared with statistics in the literature. The proportion of women meeting depression and anxiety cut-offs on the PDSQ were lower than for the EPDS and the SCL-90R. The Cohens Kappa index ( k) indicated poor to fair agreement between the measures in classifying pregnant women as depressed or anxious. The PDSQ subscales may not be appropriate for the pregnant population. Research into instruments more specific to pregnant and postpartum women are needed to determine the prevalence of psychiatric disorders in this population.

Applying CSM-CERES-Maize to define a sowing window for irrigated maize crop - The Riacho´s Farm case study

Directory of Open Access Journals (Sweden)

Denise Freitas Silva

2011-08-01

Full Text Available Irrigation use constitutes an alternative to improve maize production in Central Minas Gerais State, Brazil. However, even under adequate water supply conditions, other environmental factors may influence maize crop growth and development and may, ultimately, affect grain yield. This study aimed to establish a sowing window for irrigated maize crop, based on simulation results obtained with the decision support model CSM-CERES-Maize. Simulations were made for crop management conditions of Riacho´s Farm, located in Matozinhos, Minas Gerais State, Brazil. It was employed the model´s seasonal tool, along with a data set containing 46 years of weather data records, to simulate maize yield for weekly sowing scenarios, starting on August 1st and ending on July 24th of each year. One defined an irrigated maize sowing window, taking into account the yield break risk that a farmer would be willing to take. The model proved to be an interesting tool to assist in decision making, regarding crop and irrigation management, for an irrigated maize production system. Assuming a 10% yield break in the expected average maximum maize yield, it was defined as sowing window, the period from January 23rd to March 6th, with February 20th as the best sowing date. Other sowing windows may be established according to the risk that the farmer would be willing to take.

Precificação de consultoria empresarial com a contribuição das estratégias de apreçamento = Entrepreneurial Counseling Pricing with Pricing Strategy Contribution

OpenAIRE

Nivaldo João dos Santos; Erves Ducati; Antonio Cezar Bornia

2008-01-01

A precificação de serviços de consultoria também pode se beneficiar dos conceitos e idéias das estratégias de apreçamento de bens de consumo de massa, especificamente na área de consultoria de gestão empresarial. Apesar deste campo ser dominado por grandes corporações multinacionais, ainda existe espaço para empresas e profissionais nacionais. Por se tratar de mercado que envolve valores de grande magnitude, imaginasse que as instituições de sucesso adotem estratégia de apreçamento. Neste tra...

Contrôle hormonal des caractéristiques des fibres musculaires après la naissance

OpenAIRE

Cassar-Malek, Isabelle; Listrat, Anne; Picard, Brigitte

1998-01-01

Après la naissance, la croissance et les propriétés contractiles et métaboliques des fibres musculaires sont soumises à une régulation endocrinienne complexe. A l’exception des glucocorticoïdes, la plupart des hormones présente une action anabolique sur le tissu musculaire. Leur influence sur les caractéristiques des fibres est cependant très différente. Ainsi, les hormones somatotropes affectent peu la composition en fibres des muscles. La GH, comme l’IGF-1, régulerait cependant l’expression...

« Points de suture ». Panser l’interdépendance humaine dans quatre récits français contemporains

Directory of Open Access Journals (Sweden)

Chloé Brendlé

2018-04-01

Full Text Available Comment rendre visibles les liens qui unissent les êtres humains d’un monde globalisé et médiatisé ? L’article aborde dans le domaine littéraire cette question posée par les théories du care. Il dégage des poétiques de l’interdépendance à partir de quatre récits d’auteurs français contemporains (Annie Ernaux, Laurent Mauvignier, Emmanuel Carrère, Maylis de Kerangal. Partant de l’analyse de la métaphore de l’« onde de choc », il met au jour une esthétique et une narratologie de la mise en relation, ainsi qu’un désir de communauté. How does one render visible the connections between human beings in a globalized and media-staged world? This article addresses such a line of questioning, which is central to theories of care, within the context of the literary field. It fleshes out a poetics of interdependence based on four narratives by contemporary French authors (Annie Ernaux, Laurent Mauvignier, Emmanuel Carrère, Maylis de Kerangal. With an analysis of the “shock-wave metaphor” as its starting point, it identifies an esthetics and a narratology of connection, as well as a yearning for community.

Apreçamento de opções de IDI usando o modelo CIR

Directory of Open Access Journals (Sweden)

José Santiago Fajardo Barbachan

2003-06-01

Full Text Available A opção de IDI da BM&F possui características peculiares que torna o seu apreçamento diferente das opções de taxa de juros mais comuns, como as de títulos de renda fixa. Este artigo desenvolve uma fórmula para apreçamento dessas opções de IDI, utilizando a precificação livre de arbitragem. O modelo utilizado considera apenas um fator estocástico: a taxa de juros livre de risco de curto prazo. A equação diferencial usada para modelar o comportamento da taxa de juros é a do modelo CIR (COX INGERSOLL & ROSS, 1985, que possui reversão à média e não permite a existência de taxas de juros nominais negativas. Também é feita uma estimação dos parâmetros do modelo proposto baseando-se em dados históricos, para então comparar o preço teórico da opção baseado nestes parâmetros com os preços de mercado e com o preço teórico considerando a modelagem de Vasicek (1977.The IDI option from the BM&F (Commodities and Futures Exchange has unusual characteristics, that make its pricing different from common interest rate options. This paper develops a closed form formula for the pricing of these IDI options, using an arbitrage-free pricing approach. The model used considers only one stochastic factor: the short-term risk-free interest rate. The differential equation used to model the behavior of the interest rate comes from the CIR (COX INGERSOLL & ROSS, 1985 model, which has mean reversion property and does not allow negative nominal interest rates. It is also done a parameter estimation of the proposed model based on historic data, and then compares the theoretical price of the option based on these parameters with the market price and with the theoretical price considering the Vasicek (1977 model.

Análise do efeito não linear do patrimônio líquido no apreçamento de fundos de investimento em ações

Directory of Open Access Journals (Sweden)

Paulo Rogério Faustino Matos

2012-01-01

Full Text Available Este artigo faz uso do Capital Asset Pricing Model (CAPM, em sua versão canônica e com extensões não lineares, visando a apreçar um painel de 75 fundos de investimento em ações no Brasil, ao longo dos últimos 11 anos. O resultado sugere que a versão linear desse arcabouço não seja capaz de apreçar ou de prever retornos reais de fundos que possuam elevados patrimônio líquido (PL e outperformance, em relação ao índice da Bolsa de Valores de São Paulo (Ibovespa, corroborando evidências anteriores. A versão não linear com thresholds baseados no PL parece lidar melhor com a questão de alfas de Jensen significativos, apesar de ser estatisticamente indicada apenas para poucos fundos com elevado PL, mas baixa outperformance. Essa é uma evidência de que, apesar de o tamanho influenciar na gestão e, possivelmente, na performance de um fundo, a modelagem de apreçamento desse efeito deve ser feita linearmente.

A MARS and MIDAS Linked Accident Simulation for Large LOCA in APR1400

International Nuclear Information System (INIS)

Choi, Young; Kim, K. R.; Kim, D. H.; Chung, B. D.

2006-01-01

A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. The objectives of this paper are to explain how to identify the MAR-MIDAS linked calculation outlines and the technical problems, including the MARS data transfer method, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables

Analysis on Containment Response Following a LBLOCA of APR1400

International Nuclear Information System (INIS)

Han, Kyu Hyun

2016-01-01

The predictions are in good agreements with the final safety analysis report, which implies the containment integrity is maintained during or after an accident like loss of coolant accident. In this study, the CONTEMPT-LT/028 was used to calculate the pressure and temperature, and in the follow-up study, CONTAIN 2.0 will be used for the pressure and temperature predictions in APR1400 reactors. Shin-Hanul Units 1 and 2 may possess different characteristics of peak pressure and temperature in containment following a large break loss-of-coolant-accident. To assess the important performance independently and to compare with prediction results presented in the final safety analysis report (FSAR) of Shin-Hanul Units 1 and 2 might be helpful to regulatory review for identifying validity of the FSAR. The end of blowdown (EOB) time during a LOCA could largely affect the peak pressure and temperature in the containment. This paper provides CONTEMPT-LT/028 prediction of the peak pressure and temperature of Shin-Hanul Units 1 and 2 following a large break loss-of-coolant-accident and compares with licensee's prediction results.

Analysis on Containment Response Following a LBLOCA of APR1400

Energy Technology Data Exchange (ETDEWEB)

Han, Kyu Hyun [KINS, Daejeon (Korea, Republic of)

2016-05-15

The predictions are in good agreements with the final safety analysis report, which implies the containment integrity is maintained during or after an accident like loss of coolant accident. In this study, the CONTEMPT-LT/028 was used to calculate the pressure and temperature, and in the follow-up study, CONTAIN 2.0 will be used for the pressure and temperature predictions in APR1400 reactors. Shin-Hanul Units 1 and 2 may possess different characteristics of peak pressure and temperature in containment following a large break loss-of-coolant-accident. To assess the important performance independently and to compare with prediction results presented in the final safety analysis report (FSAR) of Shin-Hanul Units 1 and 2 might be helpful to regulatory review for identifying validity of the FSAR. The end of blowdown (EOB) time during a LOCA could largely affect the peak pressure and temperature in the containment. This paper provides CONTEMPT-LT/028 prediction of the peak pressure and temperature of Shin-Hanul Units 1 and 2 following a large break loss-of-coolant-accident and compares with licensee's prediction results.

Big Bang et au-delà les nouveaux horizons de l'Univers

CERN Document Server

Barrau, Aurélien

2015-01-01

Notre Univers a-t-il un début ? Est-il unique ? La science moderne a révolutionné notre compréhension de l’Univers. Bien que l’étude du cosmos soit sans doute aussi ancienne que la pensée, notre image du réel est en ce moment même en train de se redessiner. Il est maintenant possible de connaître certains aspects des processus qui eurent lieu moins d’un milliardième de milliardième de milliardième de seconde après le Big Bang. À la lumière des dernières découvertes du satellite Planck, Aurélien Barrau décrit en termes simples le cosmos qui se dessine sous nos yeux. Trous noirs, modèle standard de la physique des particules, gravité… les piliers et les énigmes du Big Bang sont abordés les uns après les autres, à la manière d’une balade aux origines de l’Univers. « Parce que la science est avant tout une aventure humaine, j’ai esquissé, ici et là, en contrepoint des explications physiques fournies dans la langue la plus simple et la plus accessible possible, mon expér...

Real-time PCR quantification and diversity analysis of the functional genes aprA and dsrA of sulfate-reducing bacteria in marine sediments of the Peru continental margin and the Black Sea

OpenAIRE

Axel eSchippers; Anna eBlazejak

2011-01-01

A quantitative, real-time PCR (Q-PCR) assay for the functional gene adenosine 5´-phosphosulfate reductase (aprA) of sulfate-reducing bacteria (SRB) was designed. This assay was applied together with described Q-PCR assays for dissimilatory sulfite reductase (dsrA) and the 16S rRNA gene of total Bacteria to marine sediments from the Peru margin (0 – 121 meters below seafloor (mbsf)) and the Black Sea (0 – 6 mbsf). Clone libraries of aprA show that all isolated sequences originate from SRB...

Molecular analysis of the diversity of sulfate-reducing and sulfur-oxidizing prokaryotes in the environment, using aprA as functional marker gene.

Science.gov (United States)

Meyer, Birte; Kuever, Jan

2007-12-01

The dissimilatory adenosine-5'-phosphosulfate reductase is a key enzyme of the microbial sulfate reduction and sulfur oxidation processes. Because the alpha- and beta-subunit-encoding genes, aprBA, are highly conserved among sulfate-reducing and sulfur-oxidizing prokaryotes, they are most suitable for molecular profiling of the microbial community structure of the sulfur cycle in environment. In this study, a new aprA gene-targeting assay using a combination of PCR and denaturing gradient gel electrophoresis is presented. The screening of sulfate-reducing and sulfur-oxidizing reference strains as well as the analyses of environmental DNA from diverse habitats (e.g., microbial mats, invertebrate tissue, marine and estuarine sediments, and filtered hydrothermal water) by the new primer pair revealed an improved microbial diversity coverage and less-pronounced template-to-PCR product bias in direct comparison to those of the previously published primer set (B. Deplancke, K. R. Hristova, H. A. Oakley, V. J. McCracken, R. Aminov, R. I. Mackie, and H. R. Gaskins, Appl. Environ. Microbiol. 66:2166-2174, 2000). The concomitant molecular detection of sulfate-reducing and sulfur-oxidizing prokaryotes was confirmed. The new assay was applied in comparison with the 16S rRNA gene-based analysis to investigate the microbial diversity of the sulfur cycle in sediment, seawater, and manganese crust samples from four study sites in the area of the Lesser Antilles volcanic arc, Caribbean Sea (Caribflux project). The aprA gene-based approach revealed putative sulfur-oxidizing Alphaproteobacteria of chemolithoheterotrophic lifestyle to have been abundant in the nonhydrothermal sediment and water column. In contrast, the sulfur-based microbial community that inhabited the surface of the volcanic manganese crust was more complex, consisting predominantly of putative chemolithoautotrophic sulfur oxidizers of the Betaproteobacteria and Gammaproteobacteria.

Signoles Aude, Le Hamas au pouvoir et après ?, Toulouse, Editions Milan, 2006.

Directory of Open Access Journals (Sweden)

Jean-François Legrain

2007-11-01

Full Text Available Dans les étroites limites imposées par la collection (absence totale de notes et de bibliographie, 112 p. en format réduit, le petit livre d’Aude Signoles, Le Hamas au pouvoir et après ?, commence à combler un vide de l’édition française. Le seul livre jusque là disponible en français et entièrement consacré à Hamas remonte à 7 années maintenant ; doté de nombreuses erreurs factuelles et faisant comme si Hamas était apparu avec l’autonomie des années 1990, il ignorait tout de son passé d’Ass...

Variability of nursing care by APR-DRG and by severity of illness in a sample of nine Belgian hospitals.

Science.gov (United States)

Pirson, Magali; Delo, Caroline; Di Pierdomenico, Lionel; Laport, Nancy; Biloque, Veronique; Leclercq, Pol

2013-10-10

As soon as Diagnosis related Groups (DRG) were introduced in many hospital financing systems, most nursing research revealed that DRG were not very homogeneous with regard to nursing care. However, few studies are based on All Patient refined Diagnosis related Groups (APR-DRGs) and few of them use recent data. Objectives of this study are: (1) to evaluate if nursing activity is homogeneous by APR-DRG and by severity of illness (SOI) (2) to evaluate the outlier's rate associated with the nursing activity and (3) to compare nursing cost homogeneity per DRG and SOI. Study done in 9 Belgian hospitals on a selection of APR-DRG with more than 30 patients (7 638 inpatient stays). The evaluation of the homogeneity is based on coefficients of variation (CV). The 75th percentile + 1.5 × inter-quartile range was used to select high outliers. 25th percentile -1.5 × inter-quartile range was used to select low outliers. Nursing costs per ward were distributed on inpatient stays of each ward following two techniques (the LOS vs. the number of nursing care minutes per stay). The homogeneity of LOS by DRG and by SOI is relatively good (CV: 0.56). The homogeneity of the nursing activity by DRG is less good (CVs between 0.36 and 1.54) and is influenced by nursing activity outliers (high outliers' rate: 5.19%, low outliers' rate: 0.14%). The outlier's rate varies according to the studied variable. The high outliers' rate is higher for nursing activity than for LOS. The homogeneity of nursing costs is higher when costs are based on the LOS of patients than when based on minutes of nursing care (CVs between 0.26 and 1.46 for nursing costs based on LOS and between 0.49 and 2.04 for nursing costs based on minutes of nursing care). It is essential that the calculation of nursing cost by stay and by DRG for hospital financing purposes was based on nursing activity data, that more reflect resources used in wards, and not on LOS data. The only way to obtain this information is

L'Islam noir à Bahia d'après les travaux de l'école ethnologique brèsilienne

Directory of Open Access Journals (Sweden)

Roger Bastide

1951-03-01

Full Text Available RICARD (Robert. - L'Islam noir à Bahia d'après les travaux de l'école ethnologique brèsilienne (Primeiro Artigo do Parágrafo Depois da publicação, em frances, do livro de Nina Rodrigues sobre O animismo fetichista dos negros da Bahia e da duas memórias do Piére Etienne, parece que a França pouco tem ouvido falar dos problemas afro-brasileiras.

Vegetation cover and long-term conservation of radioactive waste packages: the case study of the CSM waste disposal facility (Manche District, France).

Science.gov (United States)

Petit-Berghem, Yves; Lemperiere, Guy

2012-03-01

The CSM is the first French waste disposal facility for radioactive waste. Waste material is buried several meters deep and protected by a multi-layer cover, and equipped with a drainage system. On the surface, the plant cover is a grassland vegetation type. A scientific assessment has been carried out by the Géophen laboratory, University of Caen, in order to better characterize the plant cover (ecological groups and associated soils) and to observe its medium and long term evolution. Field assessments made on 10 plots were complemented by laboratory analyses carried out over a period of 1 year. The results indicate scenarios and alternative solutions which could arise, in order to passively ensure the long-term safety of the waste disposal system. Several proposals for a blanket solution are currently being studied and discussed, under the auspices of international research institutions in order to determine the most appropriate materials for the storage conditions. One proposal is an increased thickness of these materials associated with a geotechnical barrier since it is well adapted to the forest plants which are likely to colonize the site. The current experiments that are carried out will allow to select the best option and could provide feedback for other waste disposal facility sites already being operated in France (CSFMA waste disposal facility, Aube district) or in other countries.

Response Time Analysis and Test of Protection System Instrument Channels for APR1400 and OPR1000

Energy Technology Data Exchange (ETDEWEB)

Lee, Chang Jae; Han, Seung; Yun, Jae Hee; Baek, Seung Min [Department of Instrumentation and Control System Engineering, KEPCO Engineering and Construction, Daejeon (Korea, Republic of); Lee, Sang Jeong [Department of Electronics Engineering, Chungnam National University, Daejeon (Korea, Republic of)

2015-07-01

Safety limits are required to maintain the integrity of physical barriers designed to prevent the uncontrolled release of radioactive materials in nuclear power plants. The safety analysis establishes two critical constraints that include an analytical limit in terms of a measured or calculated variable, and a specific time after the analytical limit is reached to begin protective action. Keeping with the nuclear regulations and industry standards, satisfying these two requirements will ensure that the safety limit will not be exceeded during the design basis event, either an anticipated operational occurrence or a postulated accident. Various studies on the setpoint determination methodology for the safety-related instrumentation have been actively performed to ensure that the requirement of the analytical limit is satisfied. In particular, the protection setpoint methodology for the advanced power reactor 1400 (APP1400) and the optimized power reactor 1000 (OPR1000) has been recently developed to cover both the design basis event and the beyond design basis event. The developed setpoint methodology has also been quantitatively validated using specific computer programs and setpoint calculations. However, the safety of nuclear power plants cannot be fully guaranteed by satisfying the requirement of the analytical limit. In spite of the response time verification requirements of nuclear regulations and industry standards, it is hard to find the studies on the systematically integrated methodology regarding the response time evaluation. In cases of APR1400 and OPR1000, the response time analysis for the plant protection system is partially included in the setpoint calculation and the response time test is separately performed via the specific plant procedure. The test technique has a drawback which is the difficulty to demonstrate completeness of timing test. The analysis technique has also a demerit of resulting in extreme times that not actually possible. Thus

Response Time Analysis and Test of Protection System Instrument Channels for APR1400 and OPR1000

International Nuclear Information System (INIS)

Lee, Chang Jae; Han, Seung; Yun, Jae Hee; Baek, Seung Min; Lee, Sang Jeong

2015-01-01

Safety limits are required to maintain the integrity of physical barriers designed to prevent the uncontrolled release of radioactive materials in nuclear power plants. The safety analysis establishes two critical constraints that include an analytical limit in terms of a measured or calculated variable, and a specific time after the analytical limit is reached to begin protective action. Keeping with the nuclear regulations and industry standards, satisfying these two requirements will ensure that the safety limit will not be exceeded during the design basis event, either an anticipated operational occurrence or a postulated accident. Various studies on the setpoint determination methodology for the safety-related instrumentation have been actively performed to ensure that the requirement of the analytical limit is satisfied. In particular, the protection setpoint methodology for the advanced power reactor 1400 (APP1400) and the optimized power reactor 1000 (OPR1000) has been recently developed to cover both the design basis event and the beyond design basis event. The developed setpoint methodology has also been quantitatively validated using specific computer programs and setpoint calculations. However, the safety of nuclear power plants cannot be fully guaranteed by satisfying the requirement of the analytical limit. In spite of the response time verification requirements of nuclear regulations and industry standards, it is hard to find the studies on the systematically integrated methodology regarding the response time evaluation. In cases of APR1400 and OPR1000, the response time analysis for the plant protection system is partially included in the setpoint calculation and the response time test is separately performed via the specific plant procedure. The test technique has a drawback which is the difficulty to demonstrate completeness of timing test. The analysis technique has also a demerit of resulting in extreme times that not actually possible. Thus

Intervention intégrée quant au risque de diabète après le diabète ...

International Development Research Centre (IDRC) Digital Library (Canada)

Les femmes ayant souffert de diabète sucré de la grossesse, un diabète temporaire qui apparaît pendant la grossesse, présentent un risque élevé de développer le diabète de type 2 après leur grossesse. Cette étude de recherche abordera le problème en Afrique du Sud par l'intermédiaire d'une intervention novatrice au ...

Molecular Analysis of the Diversity of Sulfate-Reducing and Sulfur-Oxidizing Prokaryotes in the Environment, Using aprA as Functional Marker Gene▿ †

Science.gov (United States)

Meyer, Birte; Kuever, Jan

2007-01-01

The dissimilatory adenosine-5′-phosposulfate reductase is a key enzyme of the microbial sulfate reduction and sulfur oxidation processes. Because the alpha- and beta-subunit-encoding genes, aprBA, are highly conserved among sulfate-reducing and sulfur-oxidizing prokaryotes, they are most suitable for molecular profiling of the microbial community structure of the sulfur cycle in environment. In this study, a new aprA gene-targeting assay using a combination of PCR and denaturing gradient gel electrophoresis is presented. The screening of sulfate-reducing and sulfur-oxidizing reference strains as well as the analyses of environmental DNA from diverse habitats (e.g., microbial mats, invertebrate tissue, marine and estuarine sediments, and filtered hydrothermal water) by the new primer pair revealed an improved microbial diversity coverage and less-pronounced template-to-PCR product bias in direct comparison to those of the previously published primer set (B. Deplancke, K. R. Hristova, H. A. Oakley, V. J. McCracken, R. Aminov, R. I. Mackie, and H. R. Gaskins, Appl. Environ. Microbiol. 66:2166-2174, 2000). The concomitant molecular detection of sulfate-reducing and sulfur-oxidizing prokaryotes was confirmed. The new assay was applied in comparison with the 16S rRNA gene-based analysis to investigate the microbial diversity of the sulfur cycle in sediment, seawater, and manganese crust samples from four study sites in the area of the Lesser Antilles volcanic arc, Caribbean Sea (Caribflux project). The aprA gene-based approach revealed putative sulfur-oxidizing Alphaproteobacteria of chemolithoheterotrophic lifestyle to have been abundant in the nonhydrothermal sediment and water column. In contrast, the sulfur-based microbial community that inhabited the surface of the volcanic manganese crust was more complex, consisting predominantly of putative chemolithoautotrophic sulfur oxidizers of the Betaproteobacteria and Gammaproteobacteria. PMID:17921272

Evolution of glycaemia in the rat after gamma irradiation; Evolution de la glycemie chez le rat apres irradiation gamma

Energy Technology Data Exchange (ETDEWEB)

Marble, G; Frossard, H; Breuil, L; Engler, R [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

1965-07-01

The study of glycaemia variations in the rat after irradiation has made it possible to observe not only a premature hyperglycemia but also a belated hypoglycemia whose importance and subsequent evolution seem to depend on the dose given to the animal. (authors) [French] L'etude des variations de la glycemie du rat apres irradiation a permis de noter une hyperglycemie precoce mais egalement une hypoglycemie retardee dont l'amplitude et l'evolution seraient fonction de la dose delivree a l'animal. (auteurs)

Aircraft Impact Assessment of APR1400 Reactor Containment Building

International Nuclear Information System (INIS)

Moon, Il Hwan; Kim, Do Yeon; Kim, Jae Hee; Kim, Sang Yun

2011-01-01

The implementation of a protection to withstand aircraft impact on safety-related structures and systems is basically based on a probabilistic evaluation for each site, if the licensing body doesn't require a deterministic approach. Existing nuclear power plants in Korea were designed based on the probabilistic approach, and the aircraft impact hazard remained less than a probability of 10 -7 . However, a man-made aircraft impact have been considered as a possible external accident for the nuclear power plant. New plant designs that are to be constructed in the U.S. after July 2009 must consider the effect of impact from a large commercial aircraft according to the requirements of 10 CFR 50.150. Especially, Reactor Containment Building (RCB) housing the safety-related equipment and fuels should be protected safely against aircraft crash without perforation and scabbing failure of external wall. APR1400 RCB is constructed as a prestressed concrete containment vessel (PCCV) which is surrounded by the auxiliary building housing additional safety-related equipment and other systems. In this study, the aircraft impact analyses for the RCB are carried out using Riera forcing function and aircraft model. Considered external wall thickness is 4 ft 6 in. for the cylindrical wall and 4 ft for the dome. Actual strengths of concrete and steel are considered as the material properties. For these analyses, the dynamic increment factor and concrete aging effect are considered in accordance with NEI 07-13(2011)

ÉTUDE COMPARATIVE SUR L’ÉVOLUTION DE L’ALCOOLÉMIE AU COURS DU TEMPS

Directory of Open Access Journals (Sweden)

Madalina Toma

2007-12-01

Full Text Available La consommation excessive d’alcool éthylique est connue depuis longtemps comme très dangereuse pour la santé humaine. De plus, l’alcool au volant représente, après la vitesse excessive, la deuxième cause d’accidents mortels sur la route. Quoique autorisé au volant à faibles doses dans certains pays, l’alcool met toujours en danger la vie du chauffeur et de ses passagers. Le taux d’alcool dans le sang, pour la même quantité d’éthanol consommée, varie en fonction de différents facteurs physiologiques. Il existe à l’heure actuelle de nombreuses modalités d’estimer l’évolution de l’alcoolémie au cours du temps. Nous avons essayé de démontrer que cette évolution présente une forte variabilité, en fonction du sexe, de l’age et de la physiologie individuelle

O après-coup e a reconsolidação da memória

Directory of Open Access Journals (Sweden)

Graziele Luiza Barizon Scopel Gerbasi

2015-04-01

Full Text Available Em diferentes áreas do conhecimento é reconhecido que a memória está sujeita a transformações ao longo do tempo. Partindo desse pressuposto, o objetivo do presente estudo é apresentar uma discussão compreendendo a ideia de que nossas recordações são suscetíveis a transformações e a concepção de après-coup. Há o delineamento de algumas ideias acerca da temporalidade em Psicanálise e do mecanismo de reconsolidação da memória segundo as Neurociências. Utilizando-se tais conceitos, evidenciou-se a viabilidade de se pensar uma interlocução entre a Psicanálise e as Neurociências.

[Social marketers' lack of success in using CSM discipline to harness commercial resources and increase contraceptive prevalence].

Science.gov (United States)

Davies, J

1984-01-01

Social marketers have certainly shown that the CSM discipline can quickly and cost-effectively harness commercial resources to increase contraceptive prevalence. But why hasn't the social marketing idea caught on in more countries? According to Social Marketing Forum, only a tiny number of countries have active programs after more than a decade of effort. The most likely reason for this lack of success is doubt and fear on the part of both developing countries' officials and donor agencies about allowing marketing enthusiasts--with our very noticeable advertising methods--to join the family planning fight. And what has our answer been? Usually, a head-on retort such as, "But look at all the condoms we've sold]" And that gets us nowhere, because the successful peddling of 1 not-so-impressive method doesn't begin to balance the fears of a possible backlash that brash condom promotions could bring down on official heads. The lesson we should be learning is that social marketers possess to narrow an outlook and promote a small range of products that don't enthuse decisionmakers. Hence, we are often perceived as condom salesmen--and not much more. What should we be doing? We should be selling the idea of using private sector experience to assist national development. That means social development, particularly improved health, family planning and women's education. These 3 activities have proven effective in reducing fertility and would add up to a marketing opportunity--a longterm challenge that should enthuse dicisionmakers, private sector entrepreneurs and donor agencies alike. Further, our model--the commercial sector--is renowned for branching out and secceeding in a broad range of endeavors. As an example, Procter and Gamble uses separate divisions to market different products. Initiatives already exist in many countries to harness the private sector as a development tool. Social marketers should be leading the initiative--and benefitting from it, too. full text

Replacing soybean meal for cottonseed meal on performance of lactating dairy cows.

Science.gov (United States)

Imaizumi, Hugo; De Souza, Jonas; Batistel, Fernanda; Santos, Flávio Augusto Portela

2016-01-01

Cottonseed meal (CSM) is an alternative source of protein, and previous studies have been shown that it can replace soybean meal (SBM) without decrease animal performance. However, Brazilian CSM has a different chemical composition compared with the usual CSM reported in the literature. The objective of this experiment was to evaluate the effects of replacing SBM for Brazilian CSM on performance and energy balance of mid-lactating dairy cows. Forty-two Holstein cows were used in a replicate 3 × 3 Latin square design. Increasing contents of CSM (0, 15, and 30% of dry matter (DM)) were fed in diets to replace SBM. Milk yield and feed efficiency were linearly reduced with the replacement of CSM for SBM (P = 0.001). Milk fat content tended to increase quadratically (P = 0.07) with CSM addition. Replacing SBM for CSM affected milk protein content quadratically (P = 0.05). Milk urea nitrogen and plasma urea nitrogen (PUN) tended to respond quadratically (P = 0.06 and 0.10) when CSM replaced SBM to the diets. Variation in body weight (BW) also responded quadratically as CSM replaced SBM (P = 0.05). Altogether, the findings suggest better performance when cows receive SBM diet compared with the Brazilian CSM diet.

Landslide causes: Human impacts on a Himalayan landslide swarm Les impacts humains sur une séquence de glissements de terrain dans l’Himalaya

Directory of Open Access Journals (Sweden)

Martin Haigh

2012-12-01

healing as they have in the undisturbed forest along the Kilbury Road. However, past surveys confirm that landslide numbers on the Almora Lower Mall have remained steady since 1985. Since, the impacts of this rainfall event were manifest only as increased landslide outfall, not increased numbers, the chief influences of outfall volume remain hillslope angle, height of the initial roadcut, undermining by channel incision and the fact that these hillsides exist close to criticality, their limits of stability.Les géographes se voient régulièrement sollicités pour diagnostiquer les causes des catastrophes naturelles et fournir des pistes aux décideurs politiques. Notre étude porte sur un des cataclysmes - glissements de terrain et inondations - ayant touché le district himalayen d’Almora (Uttarakhand, durant la fin de la mousson de 2010. Le phénomène a affecté des milliers de kilomètres de routes et ses ravages se sont chiffrés à plus de 125 000 000 $. Les causes ont été investiguées sur une portion de route de 7,4 km qui avait fait l’objet d’une étude antérieure. Les glissements de terrain ont été examinés un par un, avec identification d’une série d’indicateurs environnementaux rendant compte de causes possibles. Les résultats ont montré que le nombre de glissements enregistrés sur la route n’était pas inhabituel. L’étude se porta dès lors sur l’exploration des facteurs susceptibles d’avoir accru leur volume. L’opinion locale y voyait principalement des impacts humains, en particulier le développement urbain récent, ou encore certaines faiblesses géologiques. Cependant, les résultats prouvent que les impacts humains tels que la construction, la déforestation et l’effondrement des terrasses agricoles étaient associés à des glissements de moindre ampleur, tandis que les facteurs géologiques ne montraient pas de corrélations significatives avec le volume des glissements. Les facteurs de génie routier comme la pr

Behaviour of BF{sub 3} counters after in-pile irradiation; Comportement de compteurs a BF{sub 3} apres irradiation dans un reacteur

Energy Technology Data Exchange (ETDEWEB)

Verdant, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1967-07-01

The behaviour of a proportional BF{sub 3}LCT 14 NE 31 counter with aluminium cathode has been studied after irradiation from 10{sup 5} to 10{sup 6} n.cm{sup -2} in the swimming-pool reactor Triton. The pulse spectrum was only slightly modified by two successive irradiations at 10{sup 15} n.cm{sup -2}, and 1 hour after the end of the irradiation the decrease in sensitivity reached 10 to 20 per cent. One hour after irradiation at 10{sup 16} n.cm{sup -2} this decrease was 20 per cent but the pulse spectrum was affected. The advantages of an aluminium cathode with respect to a standard counter using a copper cathode and irradiated under the same conditions are given. Beforehand, it had been established that the limit for use of an aluminium-cathode counter in the presence of {gamma} radiation is about 200 R.h{sup -1}. (author) [French] Le comportement d'un compteur proportionnel a BF-3LCT 14 NE 31, a cathode d'aluminium, a ete etudie apres des irradiations de 10{sup 5} a 10{sup 6} n.cm{sup -2} dans la pile-piscine TRITON. Deux irradiations successives de 10{sup 15} n.cm{sup -2} ont peu modifie le spectre des impulsions et 1 heure apres la fin de l'exposition la perte de sensibilite etait de 10 a 20 pour cent. Une heure apres une irradiation de 10{sup 16} n.cm{sup -2}, cette perte etait de 20 pour cent mais le spectre d'impulsions etait perturbe. L'avantage d'une cathode en aluminium est mis en evidence par comparaison avec un compteur standard a cathode de cuivre irradie dans les memes conditions. En preliminaire, on avait etabli que la limite d'utilisation d'un compteur a cathode d'aluminium en presence de rayonnements {gamma} etait de l'ordre de 200 R.h{sup -1}. (auteur)

Failure Mode and Effect Analysis of the Application Software of the Safety-critical I and C System in APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, Koheun; Kim, Yong geul; Choi, Woong seok; Sohn, Se do [KEPCO Engineering and Construction, Daejeon (Korea, Republic of)

2016-10-15

In APR1400, the computer software hazard analysis is performed by hazard and operability analysis (HAZOP) method. Meanwhile, HAZOP has its limitation and cannot be considered better than fault tree analysis (FTA) or failure mode and effect (FMEA) analysis. HAZOP assumes that the system has been carefully studied, and all possible hazards, their effects or consequences and remedies are incorporated in the system. But incorporating every possible event in the design is impossible. In this light, this paper attempts to use FMEA method for evaluating the risk for safety-critical instrumentation and control (I and C) system software for NPP which is more practically than HAZOP. It is possible because the software failures are due to systematic faults that causing simultaneous failure in multiple division when the triggering event happens. This analysis is applied to safety-critical system of Shin-Hanul units 1 and 2 NPP, i.e., APR1400. Through SFMEA, the critical software failure modes and tasks that could result in CCF are identified and also evaluated to determine the associated risk level (e.g. high or intermediate or low) based on the failure effect. Biggest benefit from this analysis comparing with HAZOP is it can reveal the possible weak points and provide the guidance to the V and V team by helping to generate the test cases.

SN 2010jl: Optical to Hard X-ray Observations Reveal an Explosion Embedded In a Ten Solar Mass Cocoon

DEFF Research Database (Denmark)

Ofek, Eran O.; Zoglauer, Andreas; Boggs, Steven E.

2014-01-01

Some supernovae (SNe) may be powered by the interaction of the SN ejecta with a large amount of circumstellar matter (CSM). However, quantitative estimates of the CSM mass around such SNe are missing when the CSM material is optically thick. Specifically, current estimators are sensitive to uncer......Some supernovae (SNe) may be powered by the interaction of the SN ejecta with a large amount of circumstellar matter (CSM). However, quantitative estimates of the CSM mass around such SNe are missing when the CSM material is optically thick. Specifically, current estimators are sensitive...

Culture inavouée dans la nature, nature soumise dans la culture

Directory of Open Access Journals (Sweden)

Claude Rivière

2001-12-01

Full Text Available On peut tirer de l'idée que l'on se fait de la nature, soit une apologie de l'ordre dans le cosmos, soit un argument pour justifier l'existence d'un Dieu maître de la foudre et des saisons, soit l'enchantement d'un retour à l'état de nature supposé non conflictuel, soit enfin une conviction matérialiste selon laquelle l'homme doit dompter sa gourmandise et assurer la survie optimale de l'environnement sans le polluer. La société n'est pas à penser comme une modalité d'oubli de la nature mais en rapport d'inclusion dans la nature. Après périple philosophique de Platon à Moscovici, on déviera dans le champ des artistes peignant d'après nature et dans celui des linguistes analysant ce qui est dit contre nature. C'est la culture qui oppose nature et convention, fait et norme, matière et liberté humaine. C'est elle aussi qui nous fournit notre vocabulaire, nos classifications et nos jugements de valeur à propos de la nature. Récemment un courant écologiste se pose en protecteur sourcilleux de l'environnement et en organisateur d'un développement durable, mais dans la deep ecology, on glisse vers le culte d'une biosphère de rêve.

The role of the Northern Sea Route in the development of floating nuclear power sources and prospects of cooperation with the EU countries, BRICS and APR

International Nuclear Information System (INIS)

Shadrin, A.P.; Ignat'ev, V.S.; Ivanov, V.A.

2015-01-01

The report discusses the construction of a transportable nuclear reactor, which will become the basis for the development of floating nuclear power sources on the Northern Sea Route. In this regard, the prospects of cooperation with the countries of the European Union, BRICS and APR [ru

Measurement techniques of local parameters in the downcomer boiling experiment of APR1400

International Nuclear Information System (INIS)

Lee, Eu Hwak

2004-02-01

In order to investigate boiling phenomena experimentally in the downcomer during LBLOCA with Direct Vessel Injection (DVI), which is a new Safety Injection System (SIS) of Advanced Power Reactor 1400 MW (APR1400), several parameters should be measured through the verification of their applicability. In this study, measurement techniques of the parameters are developed for the downcomer boiling experiment; local phase velocities, local void fraction and heat flux from the heated wall. The experiment has been performed with the heated wall, which has a thickness of 8.2 cm and a height of 32.5 cm and made of the same material as the prototype (APR1400) with chrome coating against rusting. The newly developed pitot tube is applied to the measurement of local liquid velocity and its calibration curve is obtained experimentally with the consideration of the effect according to water temperature and hole size changes. The developed pitot tube measures the local liquid velocity with 0.69 % deviation and it is confirmed that the water temperature and geometrical change does not affect the calibration curve. The high-speed camera and commercial software are used to measure the local vapor velocity with the accuracy of 0.06 m/sec per pixel and the procedure is confirmed in the present study. It turns out that the vapor velocity is insensitive to void size. High-speed camera and image processing are used to measure the local void fraction with the determined intensity criterion for distinguishing each phase and the results are compared with the bulk void fraction by differential pressure transmitters. In the actual experiment, the developed method is applied successfully and the results show that the criterion of intensity has little effect on local void fraction. And, it is observed that the tendency between the measured local and bulk void faction is maintained with time. In order to measure heat flux from the heated wall, two heat flux measurement techniques are developed

Analysis of steam condensation in APR1400 IRWST for loss of coolant accident

Energy Technology Data Exchange (ETDEWEB)

Oh, Young Suk

2006-02-15

The In-Containment Refueling Water Storage Tank (IRWST) of APR1400 is installed at the bottom of containment building to promote the plant safety functions during an accident. This design feature brings about uncertainty factors which may necessitate conventional prediction of temperature and pressure of containment building improved or revised when an accident occurs. The hot steam which is released from RCS break enters the IRWST through four Pressure Relief Dampers (PRDs). It is expected to be condensed with water stored in IRWST, in which water is colder than incoming steam. The purpose of this study is to investigate the influence of IRWST and pressure relief damper on back pressure and temperature in APR1400 containment codes such as CONTEMPT-LT and GOTHIC. The comparison of codes showed that GOTHIC code be more appropriate for the prediction of containment pressure and temperature under the condition of steam condensation occurring in confined water pool. Especially, the GOTHIC has superior capability to treat multi-compartmentalized geometry This study developed one-compartment (single) model, two-compartment (separated) model, and three-dimension (3-D) model, respectively. Two compartment model separates the IRWST from the other containment compartments. In 3-D model, only the IRWST is nodalized with Cartesian modeling. The single model is developed for comparison with two-compartment model which can analyze PRD's influence. The separated model for predicting PRD's influence divides the space between containment and IRWST. 3-D model for IRWST was generated because it is not symmetric considering location of sparger, pump, and suction sump. Therefore, IRWST is simulated with not only detailed three-dimensional behavior but also independent flow paths for four PRDs. Many experimental studies for the direct-contact heat transfer in stratified steam water flows, cocurrent or countercurrent, have been performed (Segev et al., 1981; Lim et al., 1981

Analysis of steam condensation in APR1400 IRWST for loss of coolant accident

International Nuclear Information System (INIS)

Oh, Young Suk

2006-02-01

The In-Containment Refueling Water Storage Tank (IRWST) of APR1400 is installed at the bottom of containment building to promote the plant safety functions during an accident. This design feature brings about uncertainty factors which may necessitate conventional prediction of temperature and pressure of containment building improved or revised when an accident occurs. The hot steam which is released from RCS break enters the IRWST through four Pressure Relief Dampers (PRDs). It is expected to be condensed with water stored in IRWST, in which water is colder than incoming steam. The purpose of this study is to investigate the influence of IRWST and pressure relief damper on back pressure and temperature in APR1400 containment codes such as CONTEMPT-LT and GOTHIC. The comparison of codes showed that GOTHIC code be more appropriate for the prediction of containment pressure and temperature under the condition of steam condensation occurring in confined water pool. Especially, the GOTHIC has superior capability to treat multi-compartmentalized geometry This study developed one-compartment (single) model, two-compartment (separated) model, and three-dimension (3-D) model, respectively. Two compartment model separates the IRWST from the other containment compartments. In 3-D model, only the IRWST is nodalized with Cartesian modeling. The single model is developed for comparison with two-compartment model which can analyze PRD's influence. The separated model for predicting PRD's influence divides the space between containment and IRWST. 3-D model for IRWST was generated because it is not symmetric considering location of sparger, pump, and suction sump. Therefore, IRWST is simulated with not only detailed three-dimensional behavior but also independent flow paths for four PRDs. Many experimental studies for the direct-contact heat transfer in stratified steam water flows, cocurrent or countercurrent, have been performed (Segev et al., 1981; Lim et al., 1981; Kim and

Development of a Desktop Simulator for APR1400 Nuclear Power Plant

International Nuclear Information System (INIS)

Lee, J. B.

2016-01-01

It is essential for utilities to possess a full-scope simulator for operator training and operation test for operators. But it is very expensive and sometimes lack of fidelity if processes of developing the simulator and designing the plant are in parallel. It is due to the situation that simulator development stage sometimes precedes the plant design stage and modifications may occur to the design of the plant in construction stage. In an attempt to build a low cost and efficient simulator, a desktop simulator has been developed. This model is described herein. Using desktop simulators for training operators is an efficient method for familiarizing operators with their plant’s operation. A low cost and efficient desktop simulator for APR1400 has been developed, and brief features are introduced here. It is configured to mimic a full-scale simulator, and can be used for operators to be familiarized to their plant’s operation. Since the size of the simulator is small enough to be fit in a desk, it can be used in a classroom or in an office at any time. It can also be used to evaluate design changes or modifications of the plant before implementing them to the plant

Development of a Desktop Simulator for APR1400 Nuclear Power Plant

Energy Technology Data Exchange (ETDEWEB)

Lee, J. B. [KHNP Central Research Institute, Daejeon (Korea, Republic of)

2016-10-15

It is essential for utilities to possess a full-scope simulator for operator training and operation test for operators. But it is very expensive and sometimes lack of fidelity if processes of developing the simulator and designing the plant are in parallel. It is due to the situation that simulator development stage sometimes precedes the plant design stage and modifications may occur to the design of the plant in construction stage. In an attempt to build a low cost and efficient simulator, a desktop simulator has been developed. This model is described herein. Using desktop simulators for training operators is an efficient method for familiarizing operators with their plant’s operation. A low cost and efficient desktop simulator for APR1400 has been developed, and brief features are introduced here. It is configured to mimic a full-scale simulator, and can be used for operators to be familiarized to their plant’s operation. Since the size of the simulator is small enough to be fit in a desk, it can be used in a classroom or in an office at any time. It can also be used to evaluate design changes or modifications of the plant before implementing them to the plant.

Comment mesurer la relation humain-technologies-organisation ? How to measure the human-technology-organization relationship? Presentation of a symbiosis-based questionnaire for evaluating the human-technology-organization relationship Cómo medir la relación humano-tecnologías-organización ? Elaboración de un cuestionario de medición de la relación humano-tecnología-organización basado en el modelo de la simbiosis

Directory of Open Access Journals (Sweden)

Éric Brangier

2007-10-01

Full Text Available Cet article vise à restituer une recherche relative à la mise au point d’une échelle de mesure de la relation entre l’humain, la technologie et l’organisation. Tout d’abord, les auteurs débattent des différents modèles théoriques de l’acceptation des technologies (technology acceptance model, théorie de la satisfaction de l’utilisateur, la théorie de la nonconformité aux attentes, puis proposent de considérer que la relation entre l’humain, la technologie et l’organisation peut s’appréhender selon une approche symbiotique qui considère qu’humains et technologies sont reliés par des rapports de forte dépendance, voire de fusion réciproque ou de couplage mutuel. La présentation d’un modèle de la symbiose humain-technologie-organisation donne ensuite lieu à l’élaboration d’un questionnaire administré à un échantillon de 172 personnes. Enfin, les analyses soulignent que l’approche symbiotique fournit des niveaux d’explicativité très intéressants, notamment en soulignant l’importance du couplage entre l’humain et la machine, et en révélant ainsi que les liens qui tissent la relation entre l’humain, l’organisation et la machine peuvent être dits mutuellement dépendants. Cet article propose donc une alternative aux modèles qui insistent sur les conditions d’acceptation des technologies par l’humain en montrant qu’aujourd’hui les technologies contemporaines sont en passe de devenir des symbiotes qui, d’un point de vue métaphorique, se couplent avec les individus.This article aims to reconstruct research relating to the development of a measurement scale for the man-technology-organization relationship. The authors first discuss various theoretical models for technology acceptance: the technology acceptance model, user’s satisfaction theory, expectancy disconfirmation theory, and then suggest that the man-technology-organization relationship can be studied through a

Cervical spondylotic myelopathy: the clinical phenomenon and the current pathobiology of an increasingly prevalent and devastating disorder.

Science.gov (United States)

Kalsi-Ryan, Sukhvinder; Karadimas, Spyridon K; Fehlings, Michael G

2013-08-01

Cervical spondylotic myelopathy (CSM) is a common disorder involving chronic progressive compression of the cervical spinal cord due to degenerative disc disease, spondylosis, or other degenerative pathology. CSM is the most common form of spinal cord impairment and causes functional decline leading to reduced independence and quality of life. Despite a sound understanding of the disease process, clinical presentation and management, a universal definition of CSM and a standardized index of severity are not currently used universally. Work is required to develop a definition and establish clinical predictors of progression to improve management of CSM. Despite advances in decompressive and reconstructive surgery, patients are often left with residual disability. Gaps in knowledge of the pathobiology of CSM have limited therapeutic advances to complement surgery. Although the histopathologic and pathophysiologic similarities between CSM and traumatic spinal cord injury have long been acknowledged, the unique pathomechanisms of CSM remain unexplored. Increased efforts to elucidate CSM pathobiology could lead to the discovery of novel therapeutic targets for human CSM and other spinal cord diseases. Here, the natural history of CSM, epidemiology, clinical presentation, and current methods of clinical management are reported, along with the current state of basic scientific research in the field.

Validation of the All Patient Refined Diagnosis Related Group (APR-DRG) Risk of Mortality and Severity of Illness Modifiers as a Measure of Perioperative Risk.

Science.gov (United States)

McCormick, Patrick J; Lin, Hung-Mo; Deiner, Stacie G; Levin, Matthew A

2018-03-22

The All Patient Refined Diagnosis Related Group (APR-DRG) is an inpatient visit classification system that assigns a diagnostic related group, a Risk of Mortality (ROM) subclass and a Severity of Illness (SOI) subclass. While extensively used for cost adjustment, no study has compared the APR-DRG subclass modifiers to the popular Charlson Comorbidity Index as a measure of comorbidity severity in models for perioperative in-hospital mortality. In this study we attempt to validate the use of these subclasses to predict mortality in a cohort of surgical patients. We analyzed all adult (age over 18 years) inpatient non-cardiac surgery at our institution between December 2005 and July 2013. After exclusions, we split the cohort into training and validation sets. We created prediction models of inpatient mortality using the Charlson Comorbidity Index, ROM only, SOI only, and ROM with SOI. Models were compared by receiver-operator characteristic (ROC) curve, area under the ROC curve (AUC), and Brier score. After exclusions, we analyzed 63,681 patient-visits. Overall in-hospital mortality was 1.3%. The median number of ICD-9-CM diagnosis codes was 6 (Q1-Q3 4-10). The median Charlson Comorbidity Index was 0 (Q1-Q3 0-2). When the model was applied to the validation set, the c-statistic for Charlson was 0.865, c-statistic for ROM was 0.975, and for ROM and SOI combined the c-statistic was 0.977. The scaled Brier score for Charlson was 0.044, Brier for ROM only was 0.230, and Brier for ROM and SOI was 0.257. The APR-DRG ROM or SOI subclasses are better predictors than the Charlson Comorbidity Index of in-hospital mortality among surgical patients.

Fatou, Julia, Montel le grand prix des sciences mathématiques de 1918, et après

CERN Document Server

Audin, Michèle

2009-01-01

Comment Fatou et Julia ont inventA(c) ce que la (TM)on appelle aujourda (TM)hui les ensembles de Julia, avant, pendant et aprA]s la premiA]re guerre mondiale? La (TM)histoire est racontA(c)e, avec ses mathA(c)matiques, ses conflits, ses personnalitA(c)s. Elle est traitA(c)e A partir de sources nouvelles, et avec rigueur. On pourra sa (TM)y initier A la (TM)itA(c)ration des fractions rationnelles et A la dynamique complexe (ensembles de Julia, de Mandelbrot, ensembles-limites). Qui A(c)taient Pierre Fatou, Gaston Julia, Paul Montel? On y trouvera en particulier des informations sur un mathA(c)m

Improved Design of PECS to reduce Flow Instability for EU-APR1400

International Nuclear Information System (INIS)

Hwang, Do Hyun; Lee, Keunsung

2014-01-01

For EU-APR1400, PECS (Passive Ex-vessel corium retaining and Cooling System), so-called core catcher, was adopted to keep the integrity of basemat in containment by preventing MCCI (Molten Core Concrete Interaction) through retaining core debris and cooling corium outside the reactor vessel. In this paper, the improved design of PECS is presented to increase coolability by reducing flow instability in the region of cooling channel. In this paper, flow instability analysis was carried out using CFD code to find out the most improved design of PECS, which is to increase coolability by reducing bubble entrainment in the region of cooling channel. The reduction of bubble entrainment in the downcomer facilitates higher mass flow rates in the downcomer. Among presented four designed for the downcomer of PECS, the superstep design shows the highest mass flow rate and the lowest gas holdup in the downcomer as well as in the cooling channel. Compared with the existing design, the elimination of the horizontal part and the addition of an extra space above the vertical entrance to the downcomer seem to help the separation of the vapor

Corporate Sustainability Management and Its Market Benefits

Directory of Open Access Journals (Sweden)

Joonhyun Kim

2018-05-01

Full Text Available An increasing number of firms around the world are applying corporate sustainability management (CSM to their business operations, and the research interest on the effect of CSM in terms of the capital market benefit has grown rapidly under the different research settings across various countries. This study investigates whether CSM contributes to increasing firm value and improving the market response to earnings disclosure, using Korean firms as the sample. The test results show that firms with CSM reporting outperform the other firms in terms of Tobin’s Q and the market-adjusted stock returns over a year. Further, investors respond more strongly to the earnings announcement events of the CSM firms than the non-CSM firms, which is more likely to be attributed to the enhanced corporate disclosure practice of the CSM firms than an improvement in earnings quality. Our findings indicate that the shareholders of firms with CSM reporting can enjoy relatively higher market valuations and enhanced information content of earnings disclosures. In conclusion, the results show that the CSM activities in pursuit of a harmonious relationship with the various stakeholders bring different forms of market benefits to shareholders as well.

Quantum mechanics as a natural generalization of classical statistical mechanics

International Nuclear Information System (INIS)

Xu Laizi; Qian Shangwu

1994-01-01

By comparison between equations of motion of geometrical optics (GO) and that of classical statistical mechanics (CSM), it is found that there should be an analogy between GO and CSM instead of GO and classical mechanics (CM). Furthermore, by comparison between the classical limit (CL) of quantum mechanics (QM) and CSM, the authors find that CL of QM is CSM not CM, hence they demonstrated that QM is a natural generalization of CSM instead of CM

Fuel assembly design for APR1400 with low CBC

Energy Technology Data Exchange (ETDEWEB)

Hah, Chang Joo, E-mail: changhah@kings.ac.kr [Department of NPP Engineering, KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2015-04-29

APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gd rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to Δk{sub TARGET}. A set of new designed fuel assembly satisfies an objective function, min [f=∑{sub i}(Δk{sub FA}−Δk{sub i})], and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to Δk{sub TARGET} as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.

PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

DEFF Research Database (Denmark)

Zandi, Roza; Selivanova, Galina; Christensen, Camilla Laulund

2011-01-01

Small cell lung cancer (SCLC) is a highly malignant disease with poor prognosis, necessitating the need to develop new and efficient treatment modalities. PRIMA-1(Met) (p53-dependent reactivation of massive apoptosis), also known as APR-246, is a small molecule, which restores tumor suppressor...... function to mutant p53 and induces cancer cell death in various cancer types. Since p53 is mutated in more than 90% of SCLC, we investigated the ability of PRIMA-1(Met) to induce apoptosis and inhibit tumor growth in SCLC with different p53 mutations....

Analysis for the Effects of Grid Voltage Degradation on APR1400 Operation, Case Study for Egypt

International Nuclear Information System (INIS)

Hassan, Mostafa Ahmed Fouad; Koo, Chang Choong

2015-01-01

Egypt is one of the countries planning to introduce a NPP into its electrical power system. Although the Egyptian power system has sufficient capacity to integrate any commercially available nuclear unit as the total installed capacity of the power system is more than 32GWe, which is more than 10 times capacity of any nuclear unit in the range of 1000 to 1700MWe, the system is vulnerable to extreme voltage variations, especially voltage degradation during peak load conditions. These conditions can lead to voltage collapse if a counter measure, usually load shedding, is not taken in a proper time. Hence, it is necessary to analyze the effect of such conditions on the safe and economic operation of the NPP. In this paper we analyzed the effects of grid voltage degradation on the safe and economic operation of the Advanced Power Reactor (APR1400) to determine any adverse effects on the plant auxiliary loads while operating in the Egyptian power system. In this paper the effects of grid voltage degradation on the safe and economic operation of APR1400 were investigated taking into account, generator operating limits, plant safety requirements, operation modes and loading categories in order to determine any adverse effect on the plant auxiliary loads while operating in the Egyptian power system. The results of the load flow and motor starting analysis demonstrated that during normal operation the automatic voltage regulator and transformers OLTCs can mitigate the effect of grid voltage degradation without any detrimental effect on the plant auxiliary loads. During the highly unlikely LOCA condition if the grid voltage degraded below 95%, the degraded voltage relays at Class 1E 4.16 kV buses will trip the supply and load breakers and reconnect the required safety loads to the EDG after 4 minutes time delay. During this period the safety loads required for LOCA can be started and accelerated to their rated speed safely even in the worst case of expected degraded voltage

A Study on the Coupled FEM-Analysis for Reactor Vessel Lower Head of APR1400 under the Severe Accident Scenario

Energy Technology Data Exchange (ETDEWEB)

Kim, Hyonam; Namgung, Ihn [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2014-10-15

For the stabilization of the RPV the in-vessel retention strategy with external reactor vessel cooling (IVR-ERVC) is adopted in APR1400. Under this severe accident condition, a good understanding of the mechanical behavior of the reactor vessel lower head (RVLH) is necessary both for verification of structural integrity and for improving the design applying appropriate accident mitigation strategies. The purpose of this study is to develop the analysis method of the RVLH with thermo-mechanical analysis using FEM tool (ANSYS v.15) in case of core-melting severe accident condition, and then analyze the RVLH of APR1400 including creep behavior. The plastic strain can be the major cause of lower head failure on the reactor vessel, and the creep cannot be not negligible factor of the failure under the severe accident condition. In the study, we applied constant convection coefficient at assumed temperature on the outside wall of RPV and substitute creep data of SA-508. In addition, it was found that the steel ablation at the interface between corium and vessel steel is not only a thermal phenomenon in the METCOR experiments. Corrosion processes and the formation of eutectics lead to the erosion of the vessel steel at temperatures that are significantly lower than the melting temperature of steel. It called thermo-chemical attack of the corium (corrosion). Reduced wall thickness because of the thermo-chemical effect by corium increase the equivalent plastic strain, and decrease the minimum time to reach 20% creep strain.

Evaluation on thermal-hydraulic characteristics for passive safety device of APR1400

Energy Technology Data Exchange (ETDEWEB)

Yoo, Seong Yeon; Lee, S. H.; Son, M. K. [Korea Association for Nuclear Technology, Taejon (Korea, Republic of); Jee, M. S.; Chung, M. H. [Chungnam National Univ., Taejon (Korea, Republic of)

2001-07-15

To establish evaluation and verification guideline for the APR1400, thermal-hydraulic characteristics for fuel rod bundle, reactor vessel and fluidic device is analyzed using FLUENT. Scope and major results of research are as follows : Thermal-hydraulic characteristics for nuclear fuel rod bundle: design data for nuclear fuel rod bundle and structure are surveyed, and 3 x 3 sub-channel model is adopted to investigate the fluid flow and heat transfer characteristics in fuel rod bundle. Computational results are compared with the heat transfer data measured by naphthalene sublimation method, and numerical analysis and evaluation are performed at various design conditions and flow conditions. Thermal-hydraulic characteristics for reactor vessel: reactor vessel design data are surveyed to develop numerical model. Porous media model is applied for fuel rod bundle, and full-scale, three dimensional simulation is performed at actual operating conditions. Distributions of velocity, pressure and temperature are discussed. Flow characteristics for fluidic device: three dimensional numerical model for fluidic device is developed, and numerical results are compared with experimental data obtained at KAERI in order to verify numerical simulation. In addition, variation of flow rate is investigated at various elapsed times after valve operating, and flow characteristics is analyzed at low and high flow rate conditions, respectively.

Modeling of melt retention in EU-APR1400 ex-vessel core catcher

Energy Technology Data Exchange (ETDEWEB)

Granovsky, V. S.; Sulatsky, A. A.; Khabensky, V. B.; Sulatskaya, M. B. [Alexandrov Research Inst. of Technology NITI, Sosnovy Bor (Russian Federation); Gusarov, V. V.; Almyashev, V. I.; Komlev, A. A. [Saint Petersburg State Technological Univ. SPbSTU, St.Petersburg (Russian Federation); Bechta, S. [KTH, Stockholm (Sweden); Kim, Y. S. [KHNP, 1312 Gil 70, Yuseongdaero, Yuseong-gu, Daejeon (Korea, Republic of); Park, R. J.; Kim, H. Y.; Song, J. H. [KAERI, 989 Gil 111, Daedeokdaero, Yuseong-gu, Daejeon (Korea, Republic of)

2012-07-01

A core catcher is adopted in the EU-APR1400 reactor design for management and mitigation of severe accidents with reactor core melting. The core catcher concept incorporates a number of engineering solutions used in the catcher designs of European EPR and Russian WER-1000 reactors, such as thin-layer corium spreading for better cooling, retention of the melt in a water-cooled steel vessel, and use of sacrificial material (SM) to control the melt properties. SM is one of the key elements of the catcher design and its performance is critical for melt retention efficiency. This SM consists of oxide components, but the core catcher also includes sacrificial steel which reacts with the metal melt of the molten corium to reduce its temperature. The paper describes the required properties of SM. The melt retention capability of the core catcher can be confirmed by modeling the heat fluxes to the catcher vessel to show that it will not fail. The fulfillment of this requirement is demonstrated on the example of LBLOCA severe accident. Thermal and physicochemical interactions between the oxide and metal melts, interactions of the melts with SM, sacrificial steel and vessel, core catcher external cooling by water and release of non-condensable gases are modeled. (authors)

Total Counting and Spectroscopy in the Assessment of Alpha Radioactivity in Human Tissues; Determination de la Radioactivite Alpha des Tissus Humains par Dosage de l'Activite Globale et Spectroscopie; Obshchee izmerenie i spektroskopiya pri opredelenii al'fa-radioaktivnosti tkanej cheloveka; Evaluacion de la Actividad Alfa en los Tejidos Humanos por Recuento Global y Espectroscopia

Energy Technology Data Exchange (ETDEWEB)

Mayneord, W. V.; Hill, C. R. [Physics Department, Institute of Cancer Research, Royal Cancer Hospital, Clifton Avenue, Belmont, Surrey (United Kingdom)

1964-10-15

'identifier les radionucleides d'apres des mesures de la periode. L'auteur decrit deux spectrometres alpha qui ont ete utilises avec des substances tres diverses (tissus humains et echantillons du milieu ambiant). Il s'est attache particulierement au dosage du {sup 210}Po que l'on sait maintenant etre present dans certains produits alimentaires et dans des tissus humains. Il expose les methodes employees pour l'etude du {sup 239}Pu dans l'atmosphere et donne des exemples de mesures de faibles concentrations de ce radionucleide dans l'air. Il expose egalement les methodes utilisees pour le dosage du {sup 239}Pu dans les tissus humains normaux et communique quelques resultats. Il etudie la contribution du {sup 210}Po dans le debit de dose du au rayonnement naturel dans les os et les organes de reproduction humains; Il montre que cette contribution peut constituer une fraction significative de la dose totale recue. (author) [Spanish] Los autores describen sucintamente un programa de mediciones de la actividad alfa, que abarco siete anos. El programa, que se basaba inicialmente en el empleo de una sensible y sencilla tecnica de recuento, con ayuda de pantallas delgadas de sulfuro de cinc y de cadmio, comprende en la actualidad tecnicas de espectroscopia alfa especiales para fuentes de gran superficie y de baja actividad especifica. Estas tecnicas permiten medir actividades especificas de hasta 10{sup -13} c/g y pueden en ciertos casos alcanzar una resolucion energetica del orden de 40 keV, permitiendo al mismo tiempo una identificacion independiente basada en la medicion del periodo de semidesintegracion. Se describen dos espectrometros alfa utilizados para examinar una gran variedad de materias provenientes del cuerpo humano y del medio ambiente. Se ha dedicado especial atencion al estudio del {sup 210}Po que, como ahora se sabe, se halla presente en buen numero de productos alimenticios y de tejidos humanos. Asimismo, se describen tecnicas de analisis del {sup 239}Pu presente en la

Development of a Human Performance Evaluation Support System for Human Factors Validation of MCR MMI Design in APR-1400

International Nuclear Information System (INIS)

Ha, Jun Su; Seong, Poong Hyun

2005-01-01

As CRT-based display and advanced information technology were applied to advanced reactors such as APR-1400 (Advanced Power Reactor-1400), human operators' tasks became more cognitive works. As a results, Human Factors Engineering (HFE) became more important in designing the MCR (Main Control Room) MMI (Man-Machine Interface) of an advanced reactor. According to the Human Factors Engineering Program Review Model, human factors validation of MCR MMI design should be performed through performance-based tests to determine whether it acceptably supports safe operation of the plant. In order to support the evaluation of the performance, a HUman Performance Evaluation Support System (HUPESS) is in development

Cellulose/soy protein isolate composite membranes: evaluations of in vitro cytocompatibility with Schwann cells and in vivo toxicity to animals.

Science.gov (United States)

Luo, Lihua; Gong, Wenrong; Zhou, Yi; Yang, Lin; Li, Daokun; Huselstein, Celine; Wang, Xiong; He, Xiaohua; Li, Yinping; Chen, Yun

2015-01-01

To evaluate the in vitro cytocompatibility of cellulose/soy protein isolate composite membranes (CSM) with Schwann cells and in vivo toxicity to animals. A series of cellulose/soy protein isolate composite membranes (CSM) were prepared by blending, solution casting and coagulation process. The cytocompatibility of the CSM to Schwann cells were evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and by direct cells culture of Schwann cells on the surfaces of the CSM, respectively. The in vivo toxicity of the CSM to animals were also evaluated by acute toxicity testing, skin sensitization testing, pyrogen testing and intracutaneous stimulation testing, respectively, according to the ISO 10993 standard. The MTT assay showed that the cell viability of Schwann cells cultured in extracts from the CSM was higher than that from the neat cellulose membrane without containing SPI component. The direct cells culture indicated that the Schwann cells could attach and grow well on the surface of the CSM and the incorporation of SPI into cellulose contributed to improvement of cell adhesion and proliferation. The evaluations of in vivo biological safety suggested that the CSM showed no acute toxicity, no skin sensitization and no intracutaneous stimulation to the experimental animals. The CSM had in vitro cytocompatibility with Schwann cells and biological safety to animals, suggesting potential for the applications as nerve conduit for the repair of nerve defect.

22 Sanou_F 03.pmd

African Journals Online (AJOL)

hond

au niveau du corps humain, il peut s'agir d'un faux visage, de l'aspect réel d'un visage humain ; au niveau des arts plastiques, le masque peut être la reproduction d'un visage humain ou animal ; le masque peut aussi être un simple objet à l'image des masques à gaz, d'une élévation de terre, d'un abri en acier, etc. Il existe ...

Dicty_cDB: VFK143 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Q) /CSM/SL/SLC3-C/SLC352Q.Seq.d/ 1336 0.0 SFE831 (SFE831Q) /CSM/SF/SFE8-B/SFE831Q.Seq.d/ 1336 0.0 AHD492 (AHD492...Q) /CSM/AH/AHD4-D/AHD492Q.Seq.d/ 1336 0.0 AFG189 (AFG189Q) /CSM/AF/AFG1-D/AFG

Application of the risk-informed methodology for APR1400 P-T limits curve

Energy Technology Data Exchange (ETDEWEB)

Kim, K.; Namgung, I. [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2014-07-01

A reactor pressure vessel (RPV) in a nuclear power plant has operational limits of pressure and temperature to prevent a potential drastic propagation of cracks due to brittle fracture. We call it a pressure-temperature limits curve (P-T limits curve). Appendix G of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code, Section XI, provides deterministic procedures to develop the P-T limits curve for the reactor pressure vessel. Recently, an alternative risk-informed methodology has been added in the ASME Code. Risk-informed means that we can consider insights from a probabilistic risk assessment by using this methodology. This alternative methodology provides a simple procedure to develop risk-informed P-T limits for heat up, cool down, and hydrostatic test events. The risk-informed P-T limits curve is known to provide more operational flexibility, particularly for reactor pressure vessels with relatively high irradiation levels and radiation sensitive materials. In this paper, we developed both the deterministic and a risk-informed P-T limits curve for an APR1400 reactor using Appendix G of the ASME Code, Section XI and compare the results in terms of additional operational margin. (author)

Conceptual design of passive containment cooling system with air holdup tanks of improved APR+

International Nuclear Information System (INIS)

Jeon, Byong Guk; Cheon No, Hee

2014-01-01

In Korea, after the successful validation of passive auxiliary feedwater system (PAFS), a passive containment cooling system (PCCS) gets attention for future development. We suggested PCCS design based on APR+, an advanced PWR developed in Korea, and performed scoping analysis. On the extension of the simple scoping analysis, MARS simulation is performed to incorporate the behavior of water pool outside the containment as well as steam-air mixture inside the containment. Through the simulation we demonstrated the effectiveness of the air holdup tank (AHT). Also we investigated the effect of the models of heat transfer coefficients between steam-air mixture side and water side, and flow instability inside HX tubes. The presence of AHT enables us to reduce the number of required HX tubes more than half through an increase in the heat transfer coefficients due to the reduction of air fraction in the containment. Finally flow instability was observed and mitigated by putting orifice plates at the inlet of tubes, increasing height of return nozzle, and increasing a tube angle. (authors)

Impact de la dynamique de peuplement sur la distribution des glossines et des trypanosomoses dans la boucle du Mouhoun (Burkina Faso*

Directory of Open Access Journals (Sweden)

Rouamba J.

2009-03-01

Full Text Available Au Burkina-Faso, la boucle du Mouhoun constitue un foyer historique des trypanosomoses humaines africaines (THA et animales africaines (TAA, transmises par les glossines. Aujourd’hui, la THA semble avoir disparu de cette région après quelques soubresauts dans les années 1970, tandis que la TAA continue de sévir. Afin de mieux comprendre ces évolutions divergentes, nous avons mené une étude géographique basée sur l’analyse de photographies aériennes entre 1952 et 2007, ainsi que d’enquêtes de terrain sur les aspects médicaux, entomologiques et vétérinaires des trypanosomoses. Il apparaît que le paysage de cette région a connu en l’espace d’un siècle des modifications intenses, notamment du fait de l’augmentation des densités de population et des surfaces cultivées, qui n’ont pas été sans conséquences sur le nombre et la distribution des mouches tsé-tsé. Associée à la lutte médicale qui avait permis la stérilisation du réservoir humain de trypanosomes dans les années 1940, cette dégradation paysagère, accompagnée du développement des aménagements hydrauliques et d’évolutions des modalités de migration des hommes et des animaux, semble pouvoir expliquer ces disparités THA/TAA. La mise en évidence de ces facteurs, et leur prise en compte lors d’études ultérieures menées dans d’autres régions, devrait permettre de délimiter des zones d’intervention prioritaires contre les trypanosomoses et leurs vecteurs dans un contexte de lutte internationale contre ces pathologies.

The Development and Evaluation of Inherent RPCS for the APR1400

Energy Technology Data Exchange (ETDEWEB)

Choi, Jae D.; Ryu, Seok H.; Jung, Dong C.; Kim, Joon S.; Baek, Byung C.; Sung, Song K.; You, Guk J. [KNF, Daejeon (Korea, Republic of); Kim, Han G. [KHNP, Daejeon (Korea, Republic of); Chi, Sung G. [KOPEC, Daejeon (Korea, Republic of)

2008-10-15

The APR1400 RPCS (Reactor Power Cutback System) is designed to rapidly reduce the core power to eliminate the need for a reactor trip following a large load rejection or a loss of two main feedwater pumps at high power. GDC (General Design Criteria) 25 says 'Protection system requirements for reactivity control malfunctions. The protection system shall be designed to assure that SAFDL (Specified Acceptable Fuel Design Limits) are not exceeded for any single malfunction of the reactivity control systems, such as accidental withdrawal (not ejection or dropout) of control rods.' In order to comply GDC 25, CPCS (Core Protection Calculator System) will apply a big power penalty({approx} 1.3) to determine the minimum DNBR (Departure from Nucleate Boiling Ratio), the maximum LPD(Local Power Density) and reactor may immediately trip by CPCS low DNBR and high LPD during high power operation for 12-finger CEA drop. The purpose of this study is to develop the inherent RPCS to avoid unwanted reactor trips due to a 12-finger CEA drop. In order to accomplish this purpose, the CPCS should be modified to send RPCS actuation signal and not to apply power penalty due to 12-finger CEA drop for a shot period. During this period which is determined by assessment of safety, the SAFDL will not be violated without any CPCS trip function. The system and CPCS performance is evaluated to verify that CPCS trip does not occurred during 12-finger CEA drop event.

Strong late-time circumstellar interaction in the peculiar supernova iPTF14hls

Science.gov (United States)

Andrews, Jennifer E.; Smith, Nathan

2018-06-01

We present a moderate-resolution spectrum of the peculiar Type II supernova (SN) iPTF14hls taken on day 1153 after discovery. This spectrum reveals the clear signature of shock interaction with dense circumstellar material (CSM). We suggest that this CSM interaction may be an important clue for understanding the extremely unusual photometric and spectroscopic evolution seen over the first 600 d of iPTF14hls. The late-time spectrum shows a double-peaked intermediate-width H α line indicative of expansion speeds around 1000 km s-1, with the double-peaked shape hinting at a disc-like geometry in the CSM. If the CSM were highly asymmetric, perhaps in a disc or torus that was ejected from the star 3-6 yr prior to explosion, the CSM interaction could have been overrun and hidden below the SN ejecta photosphere from a wide range of viewing angles. In that case, CSM interaction luminosity would have been thermalized well below the photosphere, potentially sustaining the high luminosity without exhibiting the traditional observational signatures of strong CSM interaction (narrow H α emission and X-rays). Variations in density structure of the CSM could account for the multiple rebrightenings of the light curve. We propose that a canonical 1 × 1051 erg explosion energy with enveloped CSM interaction as seen in some recent SNe, rather than an entirely new explosion mechanism, may be adequate to explain the peculiar evolution of iPTF14hls.

Comparison of serpent and triton generated FEW group constants for APR1400 nuclear reactor core

International Nuclear Information System (INIS)

Elsawi, Mohamed A.; Alnoamani, Zainab

2015-01-01

The accuracy of full-core reactor power calculations using diffusion codes is strongly dependent on the quality of the homogenized cross sections and other few-group constants generated by lattice codes. For many years, deterministic lattice codes have been used to generate these constants using different techniques: the discrete ordinates, collision probability or the method of characteristics, just to name a few. These codes, however, show some limitations, for example, on complex geometries or near heavy absorbers as in modern pressurized water reactor (PWR) designs like the Korean Advanced Power Reactor 1400 (APR1400) core. The use of continuous-energy Monte Carlo (MC) codes to produce nuclear constants can be seen as an attractive option when dealing with fuel or reactor types that lie beyond the capabilities of conventional deterministic lattice transport codes. In this paper, the few-group constants generated by two of the state-of-the-art reactor physics codes, SERPENT and SCALE/TRITON, will be critically studied and their reliability for being used in subsequent diffusion calculations will be evaluated. SERPENT is a 3D, continuous-energy, Monte Carlo reactor physics code which has a built-in burn-up calculation capability. It has been developed at the Technical Research Center of Finland (VTT) since 2004. SCALE/TRITON, on the other hand, is a control module developed within the framework of SCALE package that enables performing deterministic 2-D transport calculations on nuclear reactor core lattices. The approach followed in this paper is as follows. First, the few-group nuclear constants for the APR1400 reactor core were generated using SERPENT (version 2.1.22) and NEWT (in SCALE version 6.1.2) codes. For both codes, the critical spectrum, calculated using the B1 method, was used as a weighting function. Second, 2-D diffusion calculations were performed using the US NRC core simulator PARCS employing the two few-group constant sets generated in the first

Analysis of Hydrogen Concentration Distribution during an SBO Accident for Shin-Ulchin APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, Jongtae; Hong, Seong Wan [Korea Atomic energy Research Institute, Daejeon (Korea, Republic of)

2013-10-15

To prohibit the accumulation of hydrogen, the containment volume is considered to reduce the hydrogen concentration, or hydrogen mitigation devices such as PARs or igniters are installed in the containment. In the case of the Fukushima NPPs, the applied strategy for the hydrogen safety is the use of a containment venting system (CVS). In this way, the hydrogen accumulated in the containment vessel is vented into the environment. One of the causes of the hydrogen explosions occurring in the containment buildings of the Fukushima NPPs is expected to be the failure of the venting system. The hydrogen was therefore easily accumulated in the containment building. It is uncertain what the ignition source for the hydrogen combustion was during the accident. However, it is not too conservative to assume that an ignition source exists at any time and any place in a containment during a core-melt accident. Shin-Ulchin 1 and 2, which are construction plants of an APR 1400, are two of the newest NPPs in Korea. They have many features to enhance the safety margin during a design-based and beyond-design-based accident. One of them is the in-containment refueling water storage tank (IRWST) located inside the containment. It is used as a sink/source for feed-bleed operation. When the core is damaged along an accident progression, the hydrogen generated in the RPV can be released into the IRWST of the APR1400 with steam and water. From a previous study, it was found that a highly concentrated hydrogen/air mixture can be developed if the hydrogen is released into the IRWST. In the case of Shin-Ulchin 1 and 2, the hydrogen mitigation strategy during a high-pressure accident such as a station blackout (SBO) is changed by installing a 3-way valve. When a severe accident management (SAM) for the plant is initiated, the flow path from a pressurizer to the IRWST is changed into a steam-generator (S/G) compartment by turning the 3-wat valve actively (pilot operated). By doing so, it is

La correction et la révision de l’écrit en français langue seconde: médiation humaine, médiation informatique Correcting and editing texts written by FSL students: human mediation vs. computer-assisted mediation

Directory of Open Access Journals (Sweden)

Chantal Dion

2003-06-01

Full Text Available L’apprentissage de la correction / révision de l’écrit par les apprenants de français langue seconde peut-elle tirer profit des correcteurs orthographiques et grammaticaux des traitements de texte ou des correcticiels spécialisés ? La nature de la médiation informatique permet-elle aux apprenants de corriger de façon efficace leurs textes et comment se compare-t-elle avec la correction humaine ? Qu’est-ce qui différencie ces deux médiations ? Des textes rédigés par des anglophones ont été soumis aux deux types de corrections, humaine et informatique, soit deux enseignantes ayant vingt ans d’expérience et la correction informatique effectuée par le correcteur orthographique et grammatical de Word et les deux correcticiels canadiens, Le correcteur 101 et Antidote. Les résultats montrent que la nature de ces médiations n’est pas comparable et que la médiation informatique, pour être efficace, nécessite la participation active, intelligente et instruite de l’utilisateur et que les correcticiels ne peuvent pas corriger efficacement des textes d’étudiants de niveau intermédiaire.Can spellcheckers or grammar correctors, be they part of a word processor or stand-alone programs, help FSL students become more adept at correcting or editing the written texts they produce? Does computer-assisted mediation enable learners to correct their work efficiently and how does it compare with human mediation? What differentiates them? Texts written by anglophone students were corrected using both methods, i.e., on the one hand, by two teachers with 20 years experience and, on the other hand, using the specialized tools available with MSWord as well as two Canadian text correction programs, Le Correcteur 101 and Antidote. It turns out that the two methods are of very different natures ; computer-based correction can only give some positive results if the users have received appropriate training enabling them to actively and

Partners in Physics with Colorado School of Mines' Society of Physics Students

Science.gov (United States)

Moore, Shirley; Stilwell, Matthew; Boerner, Zach

2011-04-01

The Colorado School of Mines (CSM) Society of Physics Students (SPS) revitalized in 2008 and has since blown up with outreach activity, incorporating all age levels into our programs. In Spring 2010, CSM SPS launched a new program called Partners in Physics. Students from Golden High School came to CSM where they had a college-level lesson on standing waves and their applications. These students then joined volunteers from CSM in teaching local elementary school students about standing waves beginning with a science show. The CSM and high school students then helped the children to build make-and-take demonstrations incorporating waves. This year, rockets are the theme for Partners in Physics and we began with demonstrations with local middle school students. In Spring 2011, CSM SPS will be teaching elementary school students about projectile motion and model rockets along with these middle school students. Colorado School of Mines Department of Physics

Removal of radiostrontium from man; Elimination du radiostrontium de l'organisme humain; Vyvedenie radioaktivnogo strontsiya iz organizma cheloveka; Eliminacion del radioestroncio por el organismo humano

Energy Technology Data Exchange (ETDEWEB)

Spencer, H. [Edward Hines, Jr. Hospital Hines, IL (United States)

1963-02-15

radioisotope {sup 85}Sr dont la periode est relativement courte, servait d'indicateur. Apres avoir administre, par voie intraveineuse et par voie buccale, une meme dose de {sup 85}Sr, on a etudie les taux plasmatiques et les excretions urinaires et fecales. On a constate que, quel que soit le mode d'administration, l'excretion de {sup 85}Sr se faisait avant tout par l'intermediaire des reins. Une moyenne de 20% de la dose administree par voie buccale etait absorbee a partir de l'intestin; d'autre part, un grand nombre de sujets ont excrete dans l'urine, en 12 jours, environ 50% de la dose absorbee. Par ailleurs, des etudes, au cours desquelles on administrait simultanement des doses de {sup 85}Sr et de {sup 45}Ca par voie buccale ont montre que l'organisme marque une preference pour l'absorption de {sup 45}Ca et pour l'excretion de {sup 85}Sr, le rapport d'absorption entre {sup 45}Ca et {sup 85}Sr etant de 2,6:1. Pour ce qui est du {sup 85}Sr, les etudes faites sur les memes personnes pour une forte et une faible ingestion de calcium ont montre que, chez la plupart des sujets, l'ingestion de calcium en forte quantite n'entrauiait aucune modification notable de l'absorption de {sup 85}Sr. Vu que l 'excretion urinaire de {sup 85}Sr allait de pair avec l'excretion urinaire de calcium, on a fait intervenir divers agents pour stimulei l'excretion de calcium. L'injection intraveineuse du calcium et du strontium stables ou l'administration par voie buccale de chlorure d'ammonium-seule ou associee a l'ingestion intraveineuse de calcium et de certains agents de chelation-se sont revelees efficaces pour eliminer le radiostrontium de l'organisme humain, meme deux a quatre semaines apres avoir administre l'indicateur. D'autre part, on a etudie l'equilibre de {sup 90}Sr chez 12 jeunes sujets normaux benevoles, sans administration de radioisotope. Les resultats obtenus pour {sup 90}Sr sont analogues aux resultats pour {sup 85}Sr. (author) [Spanish] Se ha estudiado el metabolismo del

Modeling Type II-P/II-L Supernovae Interacting with Recent Episodic Mass Ejections from Their Presupernova Stars with MESA and SNEC

Science.gov (United States)

Das, Sanskriti; Ray, Alak

2017-12-01

We show how dense, compact, discrete shells of circumstellar gas immediately outside of red supergiants affect the optical light curves of Type II-P/II-L supernovae (SNe), using the example of SN 2013ej. Earlier efforts in the literature had used an artificial circumstellar medium (CSM) stitched to the surface of an evolved star that had not gone through a phase of late-stage heavy mass loss, which, in essence, is the original source of the CSM. In contrast, we allow enhanced mass-loss rate from the modeled star during the 16O and 28Si burning stages and construct the CSM from the resulting mass-loss history in a self-consistent way. Once such evolved pre-SN stars are exploded, we find that the models with early interaction between the shock and the dense CSM reproduce light curves far better than those without that mass loss and, hence, having no nearby dense CSM. The required explosion energy for the progenitors with a dense CSM is reduced by almost a factor of two compared to those without the CSM. Our model, with a more realistic CSM profile and presupernova and explosion parameters, fits observed data much better throughout the rise, plateau, and radioactive tail phases as compared to previous studies. This points to an intermediate class of supernovae between Type II-P/II-L and Type II-n SNe with the characteristics of simultaneous UV and optical peak, slow decline after peak, and a longer plateau.

Proteomic comparison by iTRAQ combined with mass spectrometry of egg white proteins in laying hens (Gallus gallus) fed with soybean meal and cottonseed meal

Science.gov (United States)

He, Tao; Zhang, Haijun; Wang, Jing; Wu, Shugeng; Yue, Hongyuan; Qi, Guanghai

2017-01-01

Cottonseed meal (CSM) is commonly used in hens’ diets to replace soybean meal (SBM). However, the molecular consequences of this substitution remains unclear. To investigate the impact of this substitution at the molecular level, iTRAQ combined with biochemical analysis was performed in Hy-Line W-36 hens supplemented with a mixed diet of CSM and SBM. Egg weight, albumen height, and Haugh unit were significantly reduced in the CSM100 group (100% crude protein of SBM replaced by CSM) compared with the SBM group (Phen diet. PMID:28813468

Développement humain, développement durable et « pays en développement » : comment articuler et mesurer les différentes dimensions ?

Directory of Open Access Journals (Sweden)

Bruno Boidin

2004-02-01

Full Text Available Cet article cherche à préciser la place qu’occupent les différentes dimensions du développement durable au sein de l’analyse économique du développement, et en particulier les dimensions humaine et sociale. Ceci nous amène à considérer les relations complexes entre les différents actifs (santé, éducation, capital social…, marquées par des effets d’irréversibilité qui peuvent remettre en cause la durabilité. Se pose alors la question de la mesure du développement durable prenant en compte ces articulations entre les dimensions. Une grille d’évaluation des mesures synthétiques du développement durable est proposée et appliquée à une sélection d’indicateurs.This article seeks to specify the place of various dimensions of sustainable development within development economics, in particular human and social dimensions. This leads us to consider the complex relations between the various assets (health, education, social capital…, characterized by irreversibility effects which can jeopardize sustainability. It is therefore necessary to find a measure of sustainable development, taking into account these interactions between dimensions. We propose criteria to evaluate synthetic measurements of sustainable development, and apply them to selected indicators.

Isolation and characterization of cobalt-sensitive mutant of Neurospora crassa

Directory of Open Access Journals (Sweden)

Krishnapuram Rashmi

2014-12-01

Full Text Available Objective: To isolate and demonstrate the mechanism of metal transport in cobalt-sensitive mutant (CSM of Neurospora crassa (N. crassa. Methods: Isolation of CSM of N. crassa, I50 determination, growth measurements, metal ion uptake studies and sexual crosses were performed to determine the mechanism of sensitivity and locus. Results: CSMs of N. crassa were isolated by mutagenesis with diethyl sulfate. More than 500 isolates were screened and out of these isolates, CSM-I was 5-fold and CSM-II was 10-fold sensitive to Co on liquid medium as compared to the wild type. Compositional analysis of cell wall revealed the decrease in total phosphate content. N. crassa CSM bound much less cobalt to cell wall fraction than wild type. The data indicated closer linkage between resistance and mating type locus (mat, which is, located on LG I. Conclusions: A CSM of N. crassa is 5-fold more sensitive than wild type and cross sensitive to nickel and copper and hyper-accumulates 2-4 fold more toxic metal ions over wild type. The mechanism for sensitivity is decreased in cobalt-binding to cell wall fraction and increased intracellular uptake. N. crassa-acon-3 morphologically resembles the CSM, cobalt-sensitive and maps to similar locus.

Predicting prostate cancer-specific outcome after radical prostatectomy among men with very high-risk cT3b/4 PCa: a multi-institutional outcome study of 266 patients.

Science.gov (United States)

Moltzahn, F; Karnes, J; Gontero, P; Kneitz, B; Tombal, B; Bader, P; Briganti, A; Montorsi, F; Van Poppel, H; Joniau, S; Spahn, M

2015-03-01

The value of radical prostatectomy (RP) as an approach for very high-risk prostate cancer (PCa) patients is controversial. To examine the risk of 10-year cancer-specific mortality (CSM) and other-cause mortality (OCM) according to clinical and pathological characteristics of very high-risk cT3b/4 PCa patients treated with RP as the primary treatment option. In a multi-institutional cohort, 266 patients with very high-risk cT3b/4 PCa treated with RP were identified. All patients underwent RP and pelvic lymph-node dissection. Competing-risk analyses assessed 10-year CSM and OCM before and after stratification for age and Charlson comorbidity index (CCI). Overall, 34 (13%) patients died from PCa and 73 (28%) from OCM. Ten-year CSM and OCM rates ranged from 5.6% to 12.9% and from 10% to 38%, respectively. OCM was the leading cause of death in all subgroups. Age and comorbidities were the main determinants of OCM. In healthy men, CSM rate did not differ among age groups (10-year CSM rate for ⩽64, 65-69 and ⩾70 years: 16.2%, 11.5% and 17.1%, respectively). Men with a CCI ⩾1 showed a very low risk of CSM irrespective of age (10-year CSM: 5.6-6.1%), whereas the 10-year OCM rates increased with age up to 38% in men ⩾70 years. Very high-risk cT3b/4 PCa represents a heterogeneous group. We revealed overall low CSM rates despite the highly unfavorable clinical disease. For healthy men, CSM was independent of age, supporting RP even for older men. Conversely, less healthy patients had the highest risk of dying from OCM while sharing very low risk of CSM, indicating that this group might not benefit from an aggressive surgical treatment. Outcome after RP as the primary treatment option in cT3b/4 PCa patients is related to age and comorbidity status.

Drop size measurements and entrainment in APR1400 during LBLOCA reflood phase

Energy Technology Data Exchange (ETDEWEB)

Lee, Eo Hwak

2010-02-15

A study has been performed to investigate droplet size in the nuclear reactor of APR1400 during LBLOCA reflood phase and to develop droplet entrainment and deposition models for SPACE (Safety and Performance CodE) which is a safety analysis tool for PWR being developed in Korea. A freezing technique for measuring the size of droplets was developed to obtain the droplet size distribution in horizontal annular flow in a pipe with a 37.1 mm diameter. Droplets are frozen by using an extremely low temperature nitrogen gas with liquid film extraction. They are then photographed with a microscope and a CCD camera and measured by means of an image process. The results are compared with various experimental data. The droplet sizes measured by the freezing technique are comparable with those measured by other methods at a high superficial air velocity (of 50 m/s). However, because of the film extraction problem, the droplet sizes measured at a low superficial air velocity of less than 40 m/s are higher than those measured by other methods. A present method suggested for predicting the Sauter mean diameter is based on the maximum droplet size correlation for the experimental data, with and without liquid film extraction. The average droplet size is remarkably smaller downstream of the liquid film extractor because large droplets from the liquid film are excluded. In order to understand and to predict a heat transfer between superheated steam and droplets properly during reflood phase of LBLOCA, it is very important to measure broken droplet sizes by spacer grids. A study, therefore, has been performed to investigate droplet size in rod bundles with spacer grids and to develop a spacer grid droplet breakup model for safety analysis codes. Experiments were conducted with liquid droplets (SMD of 300∼700 μm) and various spacer grids at superficial air velocity of 10 m/s and 20 m/s based on FLECHT SEASET. The test channel and the grids were heated to 150 .deg. C to prevent

Drop size measurements and entrainment in APR1400 during LBLOCA reflood phase

International Nuclear Information System (INIS)

Lee, Eo Hwak

2010-02-01

A study has been performed to investigate droplet size in the nuclear reactor of APR1400 during LBLOCA reflood phase and to develop droplet entrainment and deposition models for SPACE (Safety and Performance CodE) which is a safety analysis tool for PWR being developed in Korea. A freezing technique for measuring the size of droplets was developed to obtain the droplet size distribution in horizontal annular flow in a pipe with a 37.1 mm diameter. Droplets are frozen by using an extremely low temperature nitrogen gas with liquid film extraction. They are then photographed with a microscope and a CCD camera and measured by means of an image process. The results are compared with various experimental data. The droplet sizes measured by the freezing technique are comparable with those measured by other methods at a high superficial air velocity (of 50 m/s). However, because of the film extraction problem, the droplet sizes measured at a low superficial air velocity of less than 40 m/s are higher than those measured by other methods. A present method suggested for predicting the Sauter mean diameter is based on the maximum droplet size correlation for the experimental data, with and without liquid film extraction. The average droplet size is remarkably smaller downstream of the liquid film extractor because large droplets from the liquid film are excluded. In order to understand and to predict a heat transfer between superheated steam and droplets properly during reflood phase of LBLOCA, it is very important to measure broken droplet sizes by spacer grids. A study, therefore, has been performed to investigate droplet size in rod bundles with spacer grids and to develop a spacer grid droplet breakup model for safety analysis codes. Experiments were conducted with liquid droplets (SMD of 300∼700 μm) and various spacer grids at superficial air velocity of 10 m/s and 20 m/s based on FLECHT SEASET. The test channel and the grids were heated to 150 .deg. C to prevent

Dicty_cDB: SLH287 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH287 (Link to dictyBase) - - - Contig-U16243-1 SLH287Z (Link... to Original site) - - SLH287Z 614 - - - - Show SLH287 Library SL (Link to library) Clone ID SLH287 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-D/SLH287Q.Seq.d/ Representative seq. ID SLH28...7Z (Link to Original site) Representative DNA sequence >SLH287 (SLH287Q) /CSM/SL/SLH2-D/SLH287Q.Seq.d/ XXXXX...6Q) /CSM/SS/SSJ6-B/SSJ636Q.Seq.d/ 1217 0.0 SLH575 (SLH575Q) /CSM/SL/SLH5-D/SLH575Q.Seq.d/ 1217 0.0 SLH287 (SLH287Q) /CSM/SL/SLH2

Dicty_cDB: SLH218 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH218 (Link to dictyBase) - - - Contig-U16325-1 SLH218F (Link to Original site) SLH2...18F 419 - - - - - - Show SLH218 Library SL (Link to library) Clone ID SLH218 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-A/SLH218Q.Seq.d/ Representative seq. ID SLH21...8F (Link to Original site) Representative DNA sequence >SLH218 (SLH218Q) /CSM/SL/SLH2-A/SLH218Q.Seq.d/ CCATG...) /CSM/SL/SLI3-C/SLI370Q.Seq.d/ 831 0.0 SLI170 (SLI170Q) /CSM/SL/SLI1-C/SLI170Q.Seq.d/ 831 0.0 SLH218 (SLH218Q) /CSM/SL/SLH2-A/SLH2

Mise à jour sur le nouveau vaccin 9-valent pour la prévention du virus du papillome humain

Science.gov (United States)

Yang, David Yi; Bracken, Keyna

2016-01-01

Résumé Objectif Informer les médecins de famille quant à l’efficacité, à l’innocuité, aux effets sur la santé publique et à la rentabilité du vaccin 9-valent contre le virus du papillome humain (VPH). Qualité des données Des articles pertinents publiés dans PubMed jusqu’en mai 2015 ont été examinés et analysés. La plupart des données citées sont de niveau I (essais randomisés et contrôlés et méta-analyses) ou de niveau II (études transversales, cas-témoins et épidémiologiques). Des rapports et recommandations du gouvernement sont aussi cités en référence. Message principal Le vaccin 9-valent contre le VPH, qui offre une protection contre les types 6, 11, 16, 18, 31, 33, 45, 52 et 58 du VPH, est sûr et efficace et réduira encore plus l’incidence des infections à VPH, de même que les cas de cancer lié au VPH. Il peut également protéger indirectement les personnes non immunisées par l’entremise du phénomène d’immunité collective. Un programme d’immunisation efficace peut prévenir la plupart des cancers du col de l’utérus. Les analyses montrent que la rentabilité du vaccin 9-valent chez les femmes est comparable à celle du vaccin quadrivalent original contre le VPH (qui protège contre les types 6, 11, 16 et 18 du VPH) en usage à l’heure actuelle. Toutefois, il faut investiguer plus en profondeur l’utilité d’immuniser les garçons avec le vaccin 9-valent contre le VPH. Conclusion en plus d’être sûr, le vaccin 9-valent protège mieux contre le VPH que le vaccin quadrivalent. Une analyse coûtefficacité en favorise l’emploi, du moins chez les adolescentes. Ainsi, les médecins devraient recommander le vaccin 9-valent à leurs patients plutôt que le vaccin quadrivalent contre le VPH.

RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System.

Directory of Open Access Journals (Sweden)

Tina Y Liu

Full Text Available CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated systems are RNA-guided adaptive immunity pathways used by bacteria and archaea to defend against phages and plasmids. Type III-A systems use a multisubunit interference complex called Csm, containing Cas proteins and a CRISPR RNA (crRNA to target cognate nucleic acids. The Csm complex is intriguing in that it mediates RNA-guided targeting of both RNA and transcriptionally active DNA, but the mechanism is not well understood. Here, we overexpressed the five components of the Thermus thermophilus (T. thermophilus Type III-A Csm complex (TthCsm with a defined crRNA sequence, and purified intact TthCsm complexes from E. coli cells. The complexes were thermophilic, targeting complementary ssRNA more efficiently at 65°C than at 37°C. Sequence-independent, endonucleolytic cleavage of single-stranded DNA (ssDNA by TthCsm was triggered by recognition of a complementary ssRNA, and required a lack of complementarity between the first 8 nucleotides (5' tag of the crRNA and the 3' flanking region of the ssRNA. Mutation of the histidine-aspartate (HD nuclease domain of the TthCsm subunit, Cas10/Csm1, abolished DNA cleavage. Activation of DNA cleavage was dependent on RNA binding but not cleavage. This leads to a model in which binding of an ssRNA target to the Csm complex would stimulate cleavage of exposed ssDNA in the cell, such as could occur when the RNA polymerase unwinds double-stranded DNA (dsDNA during transcription. Our findings establish an amenable, thermostable system for more in-depth investigation of the targeting mechanism using structural biology methods, such as cryo-electron microscopy and x-ray crystallography.

RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System.

Science.gov (United States)

Liu, Tina Y; Iavarone, Anthony T; Doudna, Jennifer A

2017-01-01

CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems are RNA-guided adaptive immunity pathways used by bacteria and archaea to defend against phages and plasmids. Type III-A systems use a multisubunit interference complex called Csm, containing Cas proteins and a CRISPR RNA (crRNA) to target cognate nucleic acids. The Csm complex is intriguing in that it mediates RNA-guided targeting of both RNA and transcriptionally active DNA, but the mechanism is not well understood. Here, we overexpressed the five components of the Thermus thermophilus (T. thermophilus) Type III-A Csm complex (TthCsm) with a defined crRNA sequence, and purified intact TthCsm complexes from E. coli cells. The complexes were thermophilic, targeting complementary ssRNA more efficiently at 65°C than at 37°C. Sequence-independent, endonucleolytic cleavage of single-stranded DNA (ssDNA) by TthCsm was triggered by recognition of a complementary ssRNA, and required a lack of complementarity between the first 8 nucleotides (5' tag) of the crRNA and the 3' flanking region of the ssRNA. Mutation of the histidine-aspartate (HD) nuclease domain of the TthCsm subunit, Cas10/Csm1, abolished DNA cleavage. Activation of DNA cleavage was dependent on RNA binding but not cleavage. This leads to a model in which binding of an ssRNA target to the Csm complex would stimulate cleavage of exposed ssDNA in the cell, such as could occur when the RNA polymerase unwinds double-stranded DNA (dsDNA) during transcription. Our findings establish an amenable, thermostable system for more in-depth investigation of the targeting mechanism using structural biology methods, such as cryo-electron microscopy and x-ray crystallography.

Two-phase flow parameters of a downcomer boiling during a postulated reflood phase of APR1400; Parametres d'ecoulement diphasique dans un ebullition a la cuve en acier pendant un refroidissement d'un APRP de APR1400

Energy Technology Data Exchange (ETDEWEB)

Byong-Jo, Yun; Dong-Jin, Euh; Chul-Hwa, Song [Korea Atomic Energy Research Inst. (Korea, Republic of)

2009-07-01

Downcomer boiling phenomena is one of the key issues for a postulated large-break LOCA (LBLOCA) in a conventional pressurized water reactor, because it can degrade the hydraulic head of the coolant in the downcomer and consequently affect the reflood flow rate for a core cooling. To investigate the thermal hydraulic behavior in the downcomer region of the APR1400, a test program for a downcomer boiling is being progressed for the reflood phase of a postulated LBLOCA. Test was performed in a one side heated rectangular test channel which was designed by adopting a full-pressure, full-height, and full-size downcomer-gap approach, but with the circumferential length was reduced 47.08-fold. The test consists of two steps: (I) for the global two-phase flow parameters and (II) for the local two-phase flow parameters. The step-I test has already been completed. In the present paper, the experimental results of the step-II test are introduced. (authors)

Consolidation and Decomposition of APR1400 NRC Design Certification Processes for Collaborative and Accelerated Processing

Energy Technology Data Exchange (ETDEWEB)

Cho, Young Chul [FNC Technology Co., Yongin (Korea, Republic of); Kang, Deog Ji [KNHP, Daejeon (Korea, Republic of)

2016-05-15

KEPCO and KHNP are conducting APR1400 Design Certification from NRC. For the proper management of processes and information, a system called RIS (Regulatory Information management System) has been implemented by FNC from 2014, and it is on the final stage. In retaining the certification from NRC, RIS will be a very essential role by providing platform for collaborative and accelerated processing of responses to RAI (Request of Additional Information). Preparation of responses to RAI with this kind of systematic approach may be the first in the world. Westinghouse is doing manually and using MS Excel to collect the processing status. Where as, RIS will enable each member can do his own job and collect the status automatically. In this paper, how collaborative and accelerated processing of responses to RAI can be enabled will be described, and further enhancements will also be discussed. It handles MS Word directory with the help of VSTO. And with the help of Aspose.Total for .NET, the prepared response to RAI meets NRC's requirements. Through some further work and direct integration with requirement management solution, RIS can be expanded to cover a prior impact notice in case of DCD being altered.

Preliminary COM3D Analysis for H{sub 2} Combustion in the APR1400 Containment

Energy Technology Data Exchange (ETDEWEB)

Kang, Hyung Seok; Kim, Jongtae; Kim, Sang-Baik; Hong, Seong-Wan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2015-10-15

In order to assure the containment integrity of APR1400, it is necessary to evaluate an overpressure buildup resulting from a propagation of hydrogen flame along the structure and wall in the containment during a severe accident using the COM3D. Korea Atomic Energy Research Institute (KAERI) established a numerical analysis system for evaluating an overpressure buildup owing to a hydrogen combustion in the containment of a nuclear power plant by importing COM3D from KIT in Germany. The COM3D has been currently used in the simulations of the combustions and explosions, together with the system of industrial risk mitigation of hydrogen and burnable gases in nuclear containment and auxiliary buildings. KAERI performed the hydrogen combustion analysis using the COM3D code with the initial hydrogen distribution calculated by the GASFLOW under assumption of 85% metal-water reaction in the reactor vessel. From the COM3D results, we can know that the pressure buildup was about 100 kPa because the flame speed was not increased above 1000 m/s and the pressure wave passed through the open spaces in the large containment.

Dicty_cDB: Contig-U03367-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Contig-U03367-1 no gap 323 - - - - 2 1 U03367 0 0 0 0 0 0 0 0 0 0 0 0 1 1 Show Contig-U03367-1 Contig... ID Contig-U03367-1 Contig update 2001. 8.29 Contig sequence >Contig-U03367-1 (Contig-U03367-1Q) /CSM_Contig/Contig...TTGCGGGTTGGCAGGACTGTNGGNAGGCATGGNCATCGGTATNNTTGGAG ATGCTNGTGTGAGGGCGAATGCT Gap no gap Contig length 323 Chro...HLXXGLXCGLAGLXXGMXIGXXGDAXVRANA own update 2004. 6. 9 Homology vs CSM-cDNA Query= Contig-U03367-1 (Contig...-U03367-1Q) /CSM_Contig/Contig-U03367-1Q.Seq.d (323 letters) Database: CSM 6905 sequ

Exploring the Physics of Unstable Nuclei

Science.gov (United States)

Volya, Alexander

In this presentation the Continuum Shell Model (CSM) approach is advertised as a powerful theoretical tool for studying physics of unstable nuclei. The approach is illustrated using 17O as an example, which is followed by a brief presentation of the general CSM formalism. The successes of the CSM are highlighted and references are provided throughout the text. As an example, the CSM is applied perturbatively to 20O allowing one to explore the effects of continuum on positions of weakly bound states and low-lying resonances, as well as to discern some effects of threshold discontinuity.

The effect of carotid sinus massage is independent of posture in patients with heart disease

DEFF Research Database (Denmark)

Mickley, H; Hansen, K N; Oxhøj, H

1989-01-01

unilateral right- and left-sided CSM performed in the supine and in the sitting position, while heart rate and systolic blood pressure were monitored. No statistically significant differences in the CSM-induced response in systolic blood pressure or heart rate were found between the two postures....... In the supine position the drop in heart rate was significantly greater after right-sided than after left-sided CSM (P less than 0.05). In only one patient (1%) was a significant carotid sinus reflex evoked. The response was cardioinhibitory with asystole for 3700 ms during right-sided, supine CSM...

Exploring the physics of unstable nuclei

International Nuclear Information System (INIS)

Volya, Alexander

2015-01-01

In this presentation the Continuum Shell Model (CSM) approach is advertised as a powerful theoretical tool for studying physics of unstable nuclei. The approach is illustrated using 17 O as an example, which is followed by a brief presentation of the general CSM formalism. The successes of the CSM are highlighted and references are provided throughout the text. As an example, the CSM is applied perturbatively to 20 O allowing one to explore the effects of continuum on positions of weakly bound states and low-lying resonances, as well as to discern some effects of threshold discontinuity. (author)

Conférence principale : Le changement climatique mondial, ses ...

International Development Research Centre (IDRC) Digital Library (Canada)

10 mai 2011 ... Écosystèmes et santé humaine ... dioxyde de carbone dans l'atmosphère « très au‑delà de la limite [historique] ... de développement humain sans surcharger son environnement ». ... Institut national pour la recherche spatiale.

Command and Service Module Communications

Science.gov (United States)

Interbartolo, Michael

2009-01-01

This viewgraph presentation examines Command and Service Module (CSM) Communications. The communication system's capabilities are defined, including CSM-Earth, CSM-Lunar Module and CSM-Extravehicular crewman communications. An overview is provided for S-band communications, including data transmission and receiving rates, operating frequencies and major system components (pre-modulation processors, unified S-band electronics, S-band power amplifier and S-band antennas). Additionally, data transmission rates, operating frequencies and the capabilities of VHF communications are described. Major VHF components, including transmitters and receivers, and the VHF multiplexer and antennas are also highlighted. Finally, communications during pre-launch, ascent, in-flight and entry are discussed. Overall, the CSM communication system was rated highly by flight controllers and crew. The system was mostly autonomous for both crew and flight controllers and no major issues were encountered during flight.

AGAINST THE WIND: RADIO LIGHT CURVES OF TYPE IA SUPERNOVAE INTERACTING WITH LOW-DENSITY CIRCUMSTELLAR SHELLS

Energy Technology Data Exchange (ETDEWEB)

Harris, Chelsea E.; Nugent, Peter E.; Kasen, Daniel N., E-mail: chelseaharris@berkeley.edu [Astronomy Department, University of California Berkeley, Berkeley, CA (United States)

2016-06-01

For decades a wide variety of observations spanning the radio through optical and on to the X-ray have attempted to uncover signs of type Ia supernovae (SNe Ia) interacting with a circumstellar medium (CSM). The goal of these studies is to constrain the nature of the hypothesized SN Ia mass-donor companion. A continuous CSM is typically assumed when interpreting observations of interaction. However, while such models have been successfully applied to core-collapse SNe, the assumption of continuity may not be accurate for SNe Ia, because shells of CSM could be formed by pre-supernova eruptions (novae). In this work, we model the interaction of SNe with a spherical, low-density, finite-extent CSM and create a suite of synthetic radio synchrotron light curves. We find that CSM shells produce sharply peaked light curves. We also identify a fiducial set of models that obey a common evolution and can be used to generate radio light curves for an interaction with an arbitrary shell. The relations obeyed by the fiducial models can be used to deduce CSM properties from radio observations; we demonstrate this by applying them to the nondetections of SN 2011fe and SN 2014J. Finally, we explore a multiple shell CSM configuration and describe its more complicated dynamics and the resultant radio light curves.

Comparisons Between Experimental and Semi-theoretical Cutting Forces of CCS Disc Cutters

Science.gov (United States)

Xia, Yimin; Guo, Ben; Tan, Qing; Zhang, Xuhui; Lan, Hao; Ji, Zhiyong

2018-05-01

This paper focuses on comparisons between the experimental and semi-theoretical forces of CCS disc cutters acting on different rocks. The experimental forces obtained from LCM tests were used to evaluate the prediction accuracy of a semi-theoretical CSM model. The results show that the CSM model reliably predicts the normal forces acting on red sandstone and granite, but underestimates the normal forces acting on marble. Some additional LCM test data from the literature were collected to further explore the ability of the CSM model to predict the normal forces acting on rocks of different strengths. The CSM model underestimates the normal forces acting on soft rocks, semi-hard rocks and hard rocks by approximately 38, 38 and 10%, respectively, but very accurately predicts those acting on very hard and extremely hard rocks. A calibration factor is introduced to modify the normal forces estimated by the CSM model. The overall trend of the calibration factor is characterized by an exponential decrease with increasing rock uniaxial compressive strength. The mean fitting ratios between the normal forces estimated by the modified CSM model and the experimental normal forces acting on soft rocks, semi-hard rocks and hard rocks are 1.076, 0.879 and 1.013, respectively. The results indicate that the prediction accuracy and the reliability of the CSM model have been improved.

Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Science.gov (United States)

Jiménez-Ortigosa, Cristina; Aimanianda, Vishukumar; Muszkieta, Laetitia; Mouyna, Isabelle; Alsteens, David; Pire, Stéphane; Beau, Remi; Krappmann, Sven; Beauvais, Anne; Dufrêne, Yves F.

2012-01-01

Aspergillus fumigatus has two chitin synthases (CSMA and CSMB) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synthases, single and double csm mutant strains were constructed and analyzed. Although there was a slight reduction in mycelial growth of the mutants, the total chitin synthase activity and the cell wall chitin content were similar in the mycelium of all of the mutants and the parental strain. In the conidia, chitin content in the ΔcsmA strain cell wall was less than half the amount found in the parental strain. In contrast, the ΔcsmB mutant strain and, unexpectedly, the ΔcsmA/ΔcsmB mutant strain did not show any modification of chitin content in their conidial cell walls. In contrast to the hydrophobic conidia of the parental strain, conidia of all of the csm mutants were hydrophilic due to the presence of an amorphous material covering the hydrophobic surface-rodlet layer. The deletion of CSM genes also resulted in an increased susceptibility of resting and germinating conidia to echinocandins. These results show that the deletion of the CSMA and CSMB genes induced a significant disorganization of the cell wall structure, even though they contribute only weakly to the overall cell wall chitin synthesis. PMID:22964252

Steady state flow evaluations for passive auxiliary feedwater system of APR

International Nuclear Information System (INIS)

Park, Jongha; Kim, Jaeyul; Seong, Hoje; Kang, Kyoungho

2012-01-01

This paper briefly introduces a methodology to evaluate steady state flow of APR+ Passive Auxiliary Feedwater System (PAFS). The PAFS is being developed as a safety grade passive system to completely replace the existing active Auxiliary Feedwater System (AFWS). Natural circulation cooling can be generally classified into the single-phase, two-phase, and boiling-condensation modes. The PAF is designed to be operated in a boiling-condensation natural circulation mode. The steady-state flow rate should be equal to the steady-state boiling/condensation rate determined by the steady-state energy and momentum balances in the PAFS. The determined steady-state flow rate can be used in the design optimization for the natural circulation loop of the PAFS through the steady-state momentum balance. Since the retarding force, which is to be balanced by the driving force in the natural circulation system design depends on the reliable evaluation of the success of a natural circulation system design depends on the reliable evaluation of the pressure loss coefficients. In PAFS, the core decay heat is released by natural circulation flow between the S G secondary side and the Passive Condensation Heat Exchanger (PCHX) that is immersed in the Passive Condensation Cooling Tank (PCCT). The PCCT is located on the top of Auxiliary building The driving force is determined by the difference between the S/G (heat Source) secondary water level and condensation liquid (heat sink) level. It will overcome retarding force at flowrate in the system, which is determined by vaporization and condensation of the steam which is generated at the S/G by the latent heat in system. In this study, the theoretical method to estimate the steady state flow rate in boiling-condensation natural circulation system is developed and compared with test results

Spectrum structure and coherent state of the two-particle Calogero-Sutherland model: an application of the pseudo-angular-momentum operator method

International Nuclear Information System (INIS)

Li Wenbo; Li Mishan; Li Yaling; Wen Xiaoyang; Yuan Guangjun; Zhang Chi; Yang Tao

2005-01-01

The generality of the Calogero-Sutherland model (CSM) is studied with the aid of its several variations. The CSM is then solved by a new approach, the pseudo-angular-momentum operator method. The symmetry in spectrum space and valid region of the parameter are discussed. Analytic expressions of the eigenstate are obtained. The coherent states of the CSM are also discussed

Regards sur la matière des quantas et des choses

CERN Document Server

Espagnat, Bernard d'

1993-01-01

La physique quantique n'est pas seulement à la base de nombreuses inventions de pointe. Elle constitue aussi une révolution conceptuelle de grande ampleur.Bien que ses implications pratiques comme ses conséquences philosophiques soient immenses, la physique quantique est encore mal connue des non-spécialistes, en partie à cause des difficultés qu'il y a à exposer ses fondements.Or c'est justement la gageure réussie de cet ouvrage. En un style clair, enjoué et dépourvu d'équations, Etienne Klein nous guide dans les profondeurs de la matière. Nous découvrons avec lui des expériences aussi étranges que celle des fentes de Young ", qui montre que la matière est à la fois onde et corpuscule et que ses caractéristiques sont en partie liées... à notre propre existence en tant qu'observateur humain! Après avoir pris connaissance de paradoxes surprenants comme celui du chat de Schrödinger _ un chat à la fois mort et vivant! _ nous abordons la mystérieuse question de la " non-séparabilité ", s...

Gestionnaire, Relations de travail et relations avec les employés (h/f ...

International Development Research Centre (IDRC) Digital Library (Canada)

Assurer l'établissement de rapports organisationnels fiables sur le rendement de la gestion des ressources humaines par rapport au Plan de mise en oeuvre des ressources humaines, au Rapport annuel du CRDI, aux tableaux de bord organisationnels et autres obligations de production de rapports en coordonnant la ...

Haïti : les pouvoirs de l'art dans Le Sang et la Mer de Gary Victor et La Belle Amour humaine de Lyonel Trouillot

Directory of Open Access Journals (Sweden)

Odile Gannier

2012-11-01

Full Text Available Dans cet article, l'auteure pose une question en écho aux événements de janvier 2010 : "comment écrire encore après les catastrophes ?". Elle en prend pour témoins les œuvres de Gary Victor et de Lyonel Trouillot (respectivement parues en 2010 et 2011 qui, pour l'une, raconte l'histoire d'une orpheline, Hérodiane, au parcours difficile, et rapporte, pour l'autre, l'enquête d'Anaïse, une étrangère, sur les traces de sa famille haïtienne. Odile Gannier analyse la construction de l'intrigue et des personnages, mais aussi les tonalités et les genres représentés dans les deux œuvres, ainsi que leurs multiples similitudes avec d'autres formes de production artistique (la peinture en particulier.

Effect of fillers on parameters of dry and swollen polymer matrix networks

Directory of Open Access Journals (Sweden)

Stojčeva-Radovanović Blaga

2002-01-01

Full Text Available The effect of nano- and micro- particle size of SiO2 on dry and swollen parameter network of the polymer matrix blends of acrylontrile-butadiene (NBR and chlorosulphonated polyethylene (CSM such as: volume and mass degree of swelling Rv and Rw; volume fraction of NBR-CSM polymer matrix in swollen gel V2 elasticity modulus G; interaction parameter between NBR-CSM polymer matrix and solvent λ and crossiinking density ν, was tested. The influence of nano-and micro- particle size of SiO2 on physical and mechanical properties, as well as effectiveness volume ratio of filiers in NBR-CSM polymer matrix at 300% elongation was tested using Einstein-Quth-Gold equation. The Kraus equation for swelling test of NBR-CSM polymer matrix containing nano- and micro- particle size of SiO2. Test results have shown that a greater interaction of nano-particie size of SiO2 with NBR-CSM polymer matrix, and possible chemical bonding, than the one of micro-silica was a consequence of a greater contact area. This results in better physical and mechanical properties.

Free harmonic oscillators, Jack polynomials, and Calogero-Sutherland systems

International Nuclear Information System (INIS)

Gurappa, N.; Panigrahi, Prasanta K.

2000-01-01

The algebraic structure and the relationships between the eigenspaces of the Calogero-Sutherland model (CSM) and the Sutherland model (SM) on a circle are investigated through the Cherednik operators. We find an exact connection between the simultaneous nonsymmetric eigenfunctions of the A N-1 Cherednik operators, from which the eigenfunctions of the CSM and SM are constructed, and the monomials. This construction allows us to simultaneously diagonalize both CSM and SM (after gauging away the Hamiltonians by suitable measures) and also enables us to write down a harmonic oscillator algebra involving the Cherednik operators, which yields the raising and lowering operators for both of these models. The connections of the CSM with free oscillators and the SM with free particles on a circle are established in a novel way. We also point out the subtle differences between the excitations of the CSM and the SM

Petites considérations polémiques et néanmoins objectives sur la recherche (en littérature) et sa diffusion (électronique)

OpenAIRE

Dozo, Björn-Olav; Provenzano, François

2012-01-01

Le présent article fait écho à certains débats qui traversent les milieux de la recherche en sciences humaines et sociales. Les acteurs de la diffusion de la recherche se réunissent (compte rendu de la rencontre qui s’est tenue au 16e salon de la revue, ayant pour thème : « revues de sciences humaines au temps d'Internet : quelles promesses ? Quelles menaces ? »), une liste de diffusion/ discussion concernant les revues en Sciences Humaines et Sociales a été créée, différents acteurs (http://...

Dicty_cDB: Contig-U01997-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Contig-U01997-1 gap included 886 2 1683026 1682230 MINUS 3 4 U01997 1 0 0 0 0 0 2 0 0 0 0 0 0 0 Show Contig...-U01997-1 Contig ID Contig-U01997-1 Contig update 2001. 8.29 Contig sequence >Contig-U01997-1 (Contig-U01997-1Q) /CSM_Contig/Contig-U01997...ATTGAAATAATATTTATTTATTTTTTTAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA Gap gap included Contig...nfkvfgieiifiyffkkkkkkkkkkkkkkkkkkk own update 2004. 6. 9 Homology vs CSM-cDNA Query= Contig-U01997-1 (Contig-U01997-1Q) /CSM_Contig.../Contig-U01997-1Q.Seq.d (896 letters) Database: CSM 6905 sequences; 5,674,871 total l

Dicty_cDB: Contig-U12545-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Contig-U12545-1 gap included 1165 3 3275272 3276395 PLUS 1 2 U12545 0 1 0 0 0 0 0 0 0 0 0 0 0 0 Show Contig...-U12545-1 Contig ID Contig-U12545-1 Contig update 2002.12.18 Contig sequence >Contig-U12545-1 (Contig-U12545-1Q) /CSM_Contig/Contig-U12545...CGTTCTAAATCACTCATTAAAAGATTAAAAATTAAANAAGGTAATATC TCACGACNGCTNNCTCATACACACN Gap gap included Contig length 11...vliknlskrkerkis*klyqlkriqlsl vknwlklvlnhslkd*klxkvishdxxliht own update 2004. 6.10 Homology vs CSM-cDNA Query= Contig...-U12545-1 (Contig-U12545-1Q) /CSM_Contig/Contig-U12545-1Q.Seq.d (1175 letters) Database: CSM 6905 s

Dicty_cDB: VHD492 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available VH (Link to library) VHD492 (Link to dictyBase) - - - Contig-U15308-1 - (Link to Original site) - - VHD492...Z 675 - - - - Show VHD492 Library VH (Link to library) Clone ID VHD492 (Link to dicty...iol.tsukuba.ac.jp/CSM/VH/VHD4-D/VHD492Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >VHD492 (VHD492Q) /CSM/VH/VHD4-D/VHD492Q.Seq.d/ XXXXXXXXXXCTTCATC...xkiipink Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value VHD492 (VHD492Q) /CSM/VH/VHD4-D/VHD492

Dicty_cDB: SLC473 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC473 (Link to dictyBase) - - - Contig-U16054-1 SLC473F (Link to Original site) SLC4...73F 698 - - - - - - Show SLC473 Library SL (Link to library) Clone ID SLC473 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-D/SLC473Q.Seq.d/ Representative seq. ID SLC47...3F (Link to Original site) Representative DNA sequence >SLC473 (SLC473Q) /CSM/SL/SLC4-D/SLC473Q.Seq.d/ AGAAA... CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC473 (SLC473Q) /CSM/SL/SLC4

Ancillary outcome measures for assessment of individuals with cervical spondylotic myelopathy.

Science.gov (United States)

Kalsi-Ryan, Sukhvinder; Singh, Anoushka; Massicotte, Eric M; Arnold, Paul M; Brodke, Darrel S; Norvell, Daniel C; Hermsmeyer, Jeffrey T; Fehlings, Michael G

2013-10-15

Narrative review. To identify suitable outcome measures that can be used to quantify neurological and functional impairment in the management of cervical spondylotic myelopathy (CSM). CSM is the leading cause of acquired spinal cord disability, causing varying degrees of neurological impairment which impact on independence and quality of life. Because this impairment can have a heterogeneous presentation, a single outcome measure cannot define the broad range of deficits seen in this population. Therefore, it is necessary to define outcome measures that characterize the deficits with greater validity and sensitivity. This review was conducted in 3 stages. Stage I: To evaluate the current use of outcome measures in CSM, PubMed was searched using the name of the outcome measure and the common abbreviation combined with "CSM" or "myelopathy." Stage II: Having identified a lack of appropriate outcome measures, we constructed criteria by which measures appropriate for assessing the various aspects of CSM could be identified. Stage III: A second literature search was then conducted looking at specified outcomes that met these criteria. All literature was reviewed to determine specificity and psychometric properties of outcomes for CSM. Nurick grade, modified Japanese Orthopaedic Association Scale, visual analogue scale (VAS) for pain, Short Form (36) Health Survey (SF-36), and Neck Disability Index were the most commonly cited measures. The Short-Form 36 Health Survey and Myelopathy Disability Index have been validated in the CSM population with multiple studies, whereas the modified Japanese Orthopaedic Association Scale score, Nurick grade, and European Myelopathy Scale each had only one study assessing psychometric characteristics. No validity, reliability, or responsiveness studies were found for the VAS or Neck Disability Index in the CSM population. We recommend that the modified Japanese Orthopaedic Association Scale, Nurick grade, Myelopathy Disability Index

413-IJBCS-Article-Dr Biego Henri

African Journals Online (AJOL)

User

humaine est clairement établie. En effet, ces .... Les valeurs entre parenthèses représentent les valeurs limites (minima et extrema). Tableau 2: .... National de Recherche Agronomique en. 2001. ... Initiative de Programme Ecosystèmes et Santé. Humaine. Centre de Recherches pour le. Développement International, p. 4.

Radiation protection measurements at Paks and its surroundings after the accident of the Chernobylsk nuclear power plant from 28 Apr 1986

International Nuclear Information System (INIS)

German, Endre; Kemenes, Laszlo; Rosa, Geza; Szabo, I.C.; Ormai, Peter; Ronaky, Jozsef; Divos, Ferenc; Varju, Bela; Horvath, Etelka.

1986-08-01

Experimental data on the contaminantion measured within a radius of 30 km from the Paks Nuclear Power Plant due to the accident of the Chernobylsk-4 reactor are given for the period between 28 Apr and 13 Jun 1986. Measurements on airborne and fallout activities, surface contamination of the ground, dose rates of γ radiation, activity concentration of the Danube, of milk, plant and food samples and the activity of human thyroid gland were carried out in the environmental control lab of the Paks NPP. According to the preliminary dose calculations the increment of the radiation exposure of the population is regarded to mount up to the average dose burden for half a year due to natural environmental radiation. (V.N.)

Dicty_cDB: SLG376 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available 572Q) /CSM/SS/SSD5-C/SSD572Q.Seq.d/ 555 e-157 CHB571 (CHB571Q) /CSM/CH/CHB5-C/CHB571Q.Seq.d/ 494 e-139 CFD492 (CFD492...Q) /CSM/CF/CFD4-D/CFD492Q.Seq.d/ 474 e-133 own update 2003.10.30 Homology vs DNA Score E Sequences

Data-driven risk identification in phase III clinical trials using central statistical monitoring.

Science.gov (United States)

Timmermans, Catherine; Venet, David; Burzykowski, Tomasz

2016-02-01

Our interest lies in quality control for clinical trials, in the context of risk-based monitoring (RBM). We specifically study the use of central statistical monitoring (CSM) to support RBM. Under an RBM paradigm, we claim that CSM has a key role to play in identifying the "risks to the most critical data elements and processes" that will drive targeted oversight. In order to support this claim, we first see how to characterize the risks that may affect clinical trials. We then discuss how CSM can be understood as a tool for providing a set of data-driven key risk indicators (KRIs), which help to organize adaptive targeted monitoring. Several case studies are provided where issues in a clinical trial have been identified thanks to targeted investigation after the identification of a risk using CSM. Using CSM to build data-driven KRIs helps to identify different kinds of issues in clinical trials. This ability is directly linked with the exhaustiveness of the CSM approach and its flexibility in the definition of the risks that are searched for when identifying the KRIs. In practice, a CSM assessment of the clinical database seems essential to ensure data quality. The atypical data patterns found in some centers and variables are seen as KRIs under a RBM approach. Targeted monitoring or data management queries can be used to confirm whether the KRIs point to an actual issue or not.

Evaluation of energy digestibility and prediction of digestible and metabolizable energy from chemical composition of different cottonseed meal sources fed to growing pigs.

Science.gov (United States)

Li, J T; Li, D F; Zang, J J; Yang, W J; Zhang, W J; Zhang, L Y

2012-10-01

The present experiment was conducted to determine the digestible energy (DE), metabolizable energy (ME) content, and the apparent total tract digestibility (ATTD) of energy in growing pigs fed diets containing one of ten cottonseed meals (CSM) collected from different provinces of China and to develop in vitro prediction equations for DE and ME content from chemical composition of the CSM samples. Twelve growing barrows with an initial body weight of 35.2±1.7 kg were allotted to two 6×6 Latin square designs, with six barrows and six periods and six diets for each. A corn-dehulled soybean meal diet was used as the basal diet, and the other ten diets were formulated with corn, dehulled soybean meal and 19.20% CSM. The DE, ME and ATTD of gross energy among different CSM sources varied largely and ranged from 1,856 to 2,730 kcal/kg dry matter (DM), 1,778 to 2,534 kcal/kg DM, and 42.08 to 60.47%, respectively. Several chemical parameters were identified to predict the DE and ME values of CSM, and the accuracy of prediction models were also tested. The best fit equations were: DE, kcal/kg DM = 670.14+31.12 CP+659.15 EE with R(2) = 0.82, RSD = 172.02, penergy varied substantially among different CSM sources, and that some prediction equations can be applied to predict DE and ME in CSM with an acceptable accuracy.

Characteristics of combustion flame sprayed nickel aluminum using a Coanda Assisted Spray Manipulation collar for off-normal deposits

Science.gov (United States)

Archibald, Reid S.

A novel flame spray collar called the Coanda Assisted Spray Manipulation collar (CSM) has been tested for use on the Sulzer Metco 5P II combustion flame spray gun. A comparison study of the stock nozzle and the CSM has been performed by evaluating the porosity, surface roughness, microhardness, tensile strength and microscopy of normal and off-normal sprayed NiAl deposits. The use of the CSM collar resulted in the need to position the sprayed coupons closer to the gun, which in turn affected the particle impact energy and particle temperatures of the NiAl powder. For the CSM, porosities had a larger scatterband, surface roughness was comparably the same, microhardness was lower, and tensile strength was higher. The microscopy analysis revealed a greater presence of unmelted particles and steeper intersplat boundaries for the CSM. For both processes, the porosity and surface roughness increased and the microhardness decreased as the spray angle decreased.

Studies of chemical interactions between chlorosulphonated polyethylene and nit rile rubber

Directory of Open Access Journals (Sweden)

Marković Gordana

2005-01-01

Full Text Available Highly polar rubbers interact with each other through their active functional groups via condensation or substitution reactions at high temperature. Chlorosulphonated polyethylene (CSM rubber is a highly reactive rubber, the reactivity of with is due to the -SO2CI groups. When CSM reacts with nit rile rubber (NBR, a chemical reaction takes place between the two rubbers at high temperature. Fourier transform infrared (FTIR studies support that CSM/NBR (50/50 w/w isothermally induces a self cross-linking blend, when cross-linking takes place via the acrylonitrile groups of NBR and the SO2CI groups or the insitu generated allyl chloride moieties of CSM. There is a loss of some -CN groups during cross-linking. This may be due to an attack on the -CN groups by HCI (produced during the heating of CSM in the presence of inherent moisture in the polymers. Amid type of linkage is formed due to cross-linking.

The structure and emerging trends of construction safety management research: a bibliometric review.

Science.gov (United States)

Liang, Huakang; Zhang, Shoujian; Su, Yikun

2018-03-29

Recently, construction safety management (CSM) practices and systems have become important topics for stakeholders to take care of human resources. However, few studies have attempted to map the global research on CSM. A comprehensive bibliometric review was conducted in this study based on multiple methods. In total, 1172 CSM-related papers from the Web of Science Core Collection database were examined. The analyses focused on publication year, country-institute, publication source, author and research topics. The results indicated that the USA, China, Australia and the UK took leading positions in CSM research. Two branches of journals were identified, namely the branch of engineering science and that of safety science and social science. Additionally, seven themes together with 28 specific topics were detected to allow researchers to track the main structure and temporal evolution of CSM research. Finally, the main research trends and potential research directions were discussed to guide the future research.

: tous les projets | Page 436 | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

Tout -, Développement, Économie, Environnement, Évaluation, Alimentation et agriculture ... Les auteurs du Rapport arabe sur le développement humain 2005 mettent en évidence un ... à savoir l'abondance de capital humain féminin qualifié dans la région du Moyen-Orient et de ... Programme: Emploi et croissance.

Porous carbon with small mesoporesas an ultra-high capacity adsorption medium

Science.gov (United States)

Gao, Biaofeng; Zhou, Haitao; Chen, De; Yang, Jianhong

2017-10-01

Resins (732-type), abundant and inexpensive resources were used to prepare porous carbon with small mesopores (CSM) by carbonization and post-chemical-activation with potassium hydroxide (KOH). The N2 adsorption measurements revealed that CSM had high surface areas (1776.5 m2 g-1), large pore volumes (1.10 cm3 g-1), and nearly optimal narrow small mesopore sizes ranging from 2 to 7 nm. CSM was used as adsorbent to investigate the adsorption behavior for Rhodamine B (RhB). Due to the optimal pore size distributions (PSD), intensive-stacking interaction, S-doped, and electrostatic attraction, the CSM exhibited an ultra-high-capacity of 1590 mg g-1 for RhB in aqueous solutions.

Dicty_cDB: VHK246 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available VH (Link to library) VHK246 (Link to dictyBase) - - - Contig-U16440-1 VHK246P (Link to Original site) VHK2...46F 617 VHK246Z 760 VHK246P 1357 - - Show VHK246 Library VH (Link to library) Clone ID VHK2...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VH/VHK2-B/VHK246Q.Seq.d/ Representative seq. ID VHK2...46P (Link to Original site) Representative DNA sequence >VHK246 (VHK246Q) /CSM/VH/VHK2-B/VHK2...y vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value VHK246 (VHK246Q) /CSM/VH/VHK2-B/VHK2

Dicty_cDB: SLH247 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH247 (Link to dictyBase) - - - Contig-U16280-1 SLH247Z (Link... to Original site) - - SLH247Z 632 - - - - Show SLH247 Library SL (Link to library) Clone ID SLH247 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-B/SLH247Q.Seq.d/ Representative seq. ID SLH24...7Z (Link to Original site) Representative DNA sequence >SLH247 (SLH247Q) /CSM/SL/SLH2-B/SLH247Q.Seq.d/ XXXXX...ant alignments: (bits) Value SLH247 (SLH247Q) /CSM/SL/SLH2-B/SLH247Q.Seq.d/ 1253 0.0 SLA487 (SLA487Q) /CSM/S

Dicty_cDB: SLH265 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH265 (Link to dictyBase) - - - Contig-U13901-1 SLH265Z (Link... to Original site) - - SLH265Z 631 - - - - Show SLH265 Library SL (Link to library) Clone ID SLH265 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-C/SLH265Q.Seq.d/ Representative seq. ID SLH26...5Z (Link to Original site) Representative DNA sequence >SLH265 (SLH265Q) /CSM/SL/SLH2-C/SLH265Q.Seq.d/ XXXXX... alignments: (bits) Value SLH265 (SLH265Q) /CSM/SL/SLH2-C/SLH265Q.Seq.d/ 1059 0.0 VFL442 (VFL442Q) /CSM/VF/V

Dicty_cDB: SLH207 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH207 (Link to dictyBase) - - - Contig-U11514-1 SLH207P (Link to Original site) SLH2...07F 689 SLH207Z 675 SLH207P 1364 - - Show SLH207 Library SL (Link to library) Clone ID SLH2...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-A/SLH207Q.Seq.d/ Representative seq. ID SLH2...07P (Link to Original site) Representative DNA sequence >SLH207 (SLH207Q) /CSM/SL/SLH2-A/SLH2...**yi Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLH207 (SLH207Q) /CSM/SL/SLH2-A/SLH2

Dicty_cDB: SLC443 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC443 (Link to dictyBase) - - - Contig-U16518-1 SLC443P (Link to Original site) SLC4...43F 466 SLC443Z 304 SLC443P 770 - - Show SLC443 Library SL (Link to library) Clone ID SLC4... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-B/SLC443Q.Seq.d/ Representative seq. ID SLC4...43P (Link to Original site) Representative DNA sequence >SLC443 (SLC443Q) /CSM/SL/SLC4-B/SLC4...Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC443 (SLC443Q) /CSM/SL/SLC4-B/SLC4

Dicty_cDB: SLC407 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC407 (Link to dictyBase) - - - Contig-U16560-1 SLC407Z (Link... to Original site) - - SLC407Z 365 - - - - Show SLC407 Library SL (Link to library) Clone ID SLC407 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-A/SLC407Q.Seq.d/ Representative seq. ID SLC40...7Z (Link to Original site) Representative DNA sequence >SLC407 (SLC407Q) /CSM/SL/SLC4-A/SLC407Q.Seq.d/ XXXXX...vvtkf*cqt e** Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC407 (SLC407Q) /CSM/SL/SLC4

Dicty_cDB: SLC404 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC404 (Link to dictyBase) - G22406 DDB0190371 Contig-U03918-1 SLC4...04E (Link to Original site) - - - - - - SLC404E 229 Show SLC404 Library SL (Link to library) Clone ID SLC4...riginal site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-A/SLC404Q.Seq.d/ ...Representative seq. ID SLC404E (Link to Original site) Representative DNA sequence >SLC404 (SLC404Q) /CSM/SL/SLC4-A/SLC4...y vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC404 (SLC404Q) /CSM/SL/SLC4-A/SLC4

Dicty_cDB: SLC413 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC413 (Link to dictyBase) - - - Contig-U15735-1 SLC413P (Link to Original site) SLC4...13F 686 SLC413Z 466 SLC413P 1152 - - Show SLC413 Library SL (Link to library) Clone ID SLC4...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-A/SLC413Q.Seq.d/ Representative seq. ID SLC4...13P (Link to Original site) Representative DNA sequence >SLC413 (SLC413Q) /CSM/SL/SLC4-A/SLC4...iknkikkknikqkkkk Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC413 (SLC413Q) /CSM/SL/SLC4

Dicty_cDB: SLC434 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC434 (Link to dictyBase) - - - Contig-U15434-1 SLC434Z (Link... to Original site) - - SLC434Z 438 - - - - Show SLC434 Library SL (Link to library) Clone ID SLC434 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-B/SLC434Q.Seq.d/ Representative seq. ID SLC43...4Z (Link to Original site) Representative DNA sequence >SLC434 (SLC434Q) /CSM/SL/SLC4-B/SLC434Q.Seq.d/ XXXXX...logy vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SLC434 (SLC434Q) /CSM/SL/SLC4-B/SLC4

Dicty_cDB: SLC450 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC450 (Link to dictyBase) - - - Contig-U16382-1 SLC450Z (Link... to Original site) - - SLC450Z 416 - - - - Show SLC450 Library SL (Link to library) Clone ID SLC450 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-C/SLC450Q.Seq.d/ Representative seq. ID SLC45...0Z (Link to Original site) Representative DNA sequence >SLC450 (SLC450Q) /CSM/SL/SLC4-C/SLC450Q.Seq.d/ XXXXX...cant alignments: (bits) Value SLC450 (SLC450Q) /CSM/SL/SLC4-C/SLC450Q.Seq.d/ 678 0.0 VFO858 (VFO858Q) /CSM/V

Dicty_cDB: SLC435 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC435 (Link to dictyBase) - - - Contig-U16260-1 SLC435E (Link... to Original site) - - - - - - SLC435E 373 Show SLC435 Library SL (Link to library) Clone ID SLC435 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-B/SLC435Q.Seq.d/ Representative seq. ID SLC43...5E (Link to Original site) Representative DNA sequence >SLC435 (SLC435Q) /CSM/SL/SLC4-B/SLC435Q.Seq.d/ GGAGA...I815Q) /CSM/SL/SLI8-A/SLI815Q.Seq.d/ 694 0.0 SLC435 (SLC435Q) /CSM/SL/SLC4-B/SLC4

THE MORPHOLOGY AND DYNAMICS OF JET-DRIVEN SUPERNOVA REMNANTS: THE CASE OF W49B

Energy Technology Data Exchange (ETDEWEB)

González-Casanova, Diego F.; De Colle, Fabio [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, A. P. 70-543, 04510 D. F. (Mexico); Ramirez-Ruiz, Enrico [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Lopez, Laura A. [MIT-Kavli Institute for Astrophysics and Space Research, 77 Massachusetts Avenue, 37-664H, Cambridge, MA 02139 (United States)

2014-02-01

The circumstellar medium (CSM) of a massive star is modified by its winds before a supernova (SN) explosion occurs, and thus the evolution of the resulting supernova remnant (SNR) is influenced by both the geometry of the explosion as well as the complex structure of the CSM. Motivated by recent work suggesting the SNR W49B was a jet-driven SN expanding in a complex CSM, we explore how the dynamics and the metal distributions in a jet-driven explosion are modified by the interaction with the surrounding environment. In particular, we perform hydrodynamical calculations to study the dynamics and explosive nucleosynthesis of a jet-driven SN triggered by the collapse of a 25 M {sub ☉} Wolf-Rayet star and its subsequent interaction with the CSM up to several hundred years following the explosion. We find that although the CSM has small-scale effects on the structure of the SNR, the overall morphology and abundance patterns are reflective of the initial asymmetry of the SN explosion. Thus, we predict that jet-driven SNRs, such as W49B, should be identifiable based on morphology and abundance patterns at ages up to several hundred years, even if they expand into a complex CSM environment.

CIRCUMSTELLAR SHELL FORMATION IN SYMBIOTIC RECURRENT NOVAE

Energy Technology Data Exchange (ETDEWEB)

Moore, Kevin; Bildsten, Lars [Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106 (United States)

2012-12-20

We present models of spherically symmetric recurrent nova shells interacting with circumstellar material (CSM) in a symbiotic system composed of a red giant (RG) expelling a wind and a white dwarf accreting from this material. Recurrent nova eruptions periodically eject material at high velocities ({approx}> 10{sup 3} km s{sup -1}) into the RG wind profile, creating a decelerating shock wave as CSM is swept up. High CSM densities cause the shocked wind and ejecta to have very short cooling times of days to weeks. Thus, the late-time evolution of the shell is determined by momentum conservation instead of energy conservation. We compute and show evolutionary tracks of shell deceleration, as well as post-shock structure. After sweeping up all the RG wind, the shell coasts at a velocity {approx}100 km s{sup -1}, depending on system parameters. These velocities are similar to those measured in blueshifted CSM from the symbiotic nova RS Oph, as well as a few Type Ia supernovae that show evidence of CSM, such as 2006X, 2007le, and PTF 11kx. Supernovae occurring in such systems may not show CSM interaction until the inner nova shell gets hit by the supernova ejecta, days to months after the explosion.

Bundled payment reimbursement for anterior and posterior approaches for cervical spondylotic myelopathy: an analysis of private payer and Medicare databases.

Science.gov (United States)

Virk, Sohrab S; Phillips, Frank M; Khan, Safdar N

2018-03-01

OBJECTIVE Cervical spondylotic myelopathy (CSM) is a progressive spinal condition that often requires surgery. Studies have shown the clinical equivalency of anterior versus posterior approaches for CSM surgery. The purpose of this study was to determine the amount and type of resources used for anterior and posterior surgical treatment of CSM by using large national databases of clinical and financial information from patients. METHODS This study consists of 2 large cohorts of patients who underwent either an anterior or posterior approach for treatment of CSM. These patients were selected from the Medicare 5% National Sample Administrative Database (SAF5) and the Humana orthopedic database (HORTHO), which is a database of patients with private payer health insurance. The outcome measures were the cost of a 90-day episode of care, as well as a breakdown of the cost components for each surgical procedure between 2005 and 2014. RESULTS A total of 16,444 patients were included in this analysis. In HORTHO, there were 10,332 and 1556 patients treated with an anterior or posterior approach for CSM, respectively. In SAF5, there were 3851 and 705 patients who were treated by an anterior or posterior approach for CSM, respectively. The mean ± SD reimbursements for anterior and posterior approaches in the HORTHO database were $20,863 ± $2014 and $23,813 ± $4258, respectively (p = 0.048). The mean ± SD reimbursements for anterior and posterior approaches in the SAF5 database were $18,219 ± $1053 and $25,598 ± $1686, respectively (p reimbursements for a rehabilitation/skilled nursing facility and hospital/inpatient care for patients who underwent a posterior approach in both the private payer and Medicare databases. In all cohorts in this study, the hospital-related reimbursement was more than double the surgeon-related reimbursement. CONCLUSIONS This study provides resource utilization information for a 90-day episode of care for both anterior and posterior approaches

Dicty_cDB: FC-BS09 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available FC (Link to library) FC-BS09 (Link to dictyBase) - - - Contig-U16215-1 FC-BS09Z (Li...nk to Original site) - - FC-BS09Z 626 - - - - Show FC-BS09 Library FC (Link to library) Clone ID FC-BS09 (Li.../dictycdb.biol.tsukuba.ac.jp/CSM/FC/FC-BS/FC-BS09Q.Seq.d/ Representative seq. ID FC-BS...09Z (Link to Original site) Representative DNA sequence >FC-BS09 (FC-BS09Q) /CSM/FC/FC-BS/FC-BS09Q.Seq....ignments: (bits) Value SSF360 (SSF360Q) /CSM/SS/SSF3-C/SSF360Q.Seq.d/ 854 0.0 FC-BS09 (FC-BS09Q) /CSM/FC/FC-BS/FC-BS

Dicty_cDB: Contig-U09694-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Contig-U09694-1 gap included 1129 1 4027135 4026071 MINUS 3 4 U09694 2 0 1 0 0 0 0 0 0 0 0 0 0 0 Show Contig...-U09694-1 Contig ID Contig-U09694-1 Contig update 2002. 9.13 Contig sequence >Contig-U09694-1 (Contig-U09694-1Q) /CSM_Contig/Contig-U0969...TTAAATTAAAACAACAACAATTTCATAATATAAATAAT Gap gap included Contig length 1129 Chromosome number (1..6, M) 1 Chr...iklkqqqfklkqqqfhninn own update 2004. 6.10 Homology vs CSM-cDNA Query= Contig-U09694-1 (Contig-U09694-1Q) /CSM_Contig/Contig...E Sequences producing significant alignments: (bits) Value Contig-U09694-1 (Contig-U09694-1Q) /CSM_Contig

Dicty_cDB: Contig-U12086-1 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available Contig-U12086-1 gap included 1101 3 5710254 5711336 PLUS 1 2 U12086 0 0 0 0 0 0 0 1 0 0 0 0 0 0 Show Contig...-U12086-1 Contig ID Contig-U12086-1 Contig update 2002.12.18 Contig sequence >Contig-U12086-1 (Contig-U12086-1Q) /CSM_Contig/Contig-U12086...ATCGGATTA Gap gap included Contig length 1101 Chromosome number (1..6, M) 3 Chromosome length 6358359 Start ...te 2004. 6.10 Homology vs CSM-cDNA Query= Contig-U12086-1 (Contig-U12086-1Q) /CSM_Contig/Contig...Sequences producing significant alignments: (bits) Value Contig-U12086-1 (Contig-U12086-1Q) /CSM_Contig/Conti... 404 e-113 Contig

Dicty_cDB: SHD492 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SH (Link to library) SHD492 (Link to dictyBase) - - - Contig-U16471-1 SHD492P (Link to Original site) SHD492...F 121 SHD492Z 819 SHD492P 920 - - Show SHD492 Library SH (Link to library) Clone ID SHD492... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SH/SHD4-D/SHD492Q.Seq.d/ Representative seq. ID SHD492...P (Link to Original site) Representative DNA sequence >SHD492 (SHD492Q) /CSM/SH/SHD4-D/SHD492....Seq.d/ 805 0.0 SHD613 (SHD613Q) /CSM/SH/SHD6-A/SHD613Q.Seq.d/ 805 0.0 SHD492 (SHD492Q) /CSM/SH/SHD4-D/SHD492

Dicty_cDB: AFK258 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available AF (Link to library) AFK258 (Link to dictyBase) - - - Contig-U15883-1 AFK258Z (Link... to Original site) - - AFK258Z 705 - - - - Show AFK258 Library AF (Link to library) Clone ID AFK258 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/AF/AFK2-C/AFK258Q.Seq.d/ Representative seq. ID AFK25...8Z (Link to Original site) Representative DNA sequence >AFK258 (AFK258Q) /CSM/AF/AFK2-C/AFK258Q.Seq.d/ XXXXX...its) Value CFC754 (CFC754Q) /CSM/CF/CFC7-C/CFC754Q.Seq.d/ 656 0.0 AFM846 (AFM846Q) /CSM/AF/AFM8-B/AFM846Q.Seq.d/ 656 0.0 AFK2

Dicty_cDB: SLH242 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH242 (Link to dictyBase) - - - Contig-U16343-1 SLH242Z (Link... to Original site) - - SLH242Z 476 - - - - Show SLH242 Library SL (Link to library) Clone ID SLH242 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-B/SLH242Q.Seq.d/ Representative seq. ID SLH24...2Z (Link to Original site) Representative DNA sequence >SLH242 (SLH242Q) /CSM/SL/SLH2-B/SLH242Q.Seq.d/ XXXXX...d/ 910 0.0 SLI231 (SLI231Q) /CSM/SL/SLI2-B/SLI231Q.Seq.d/ 910 0.0 SLH242 (SLH242Q) /CSM/SL/SLH2-B/SLH2

Dicty_cDB: SLH222 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH222 (Link to dictyBase) - - - Contig-U16475-1 SLH222Z (Link... to Original site) - - SLH222Z 433 - - - - Show SLH222 Library SL (Link to library) Clone ID SLH222 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-A/SLH222Q.Seq.d/ Representative seq. ID SLH22...2Z (Link to Original site) Representative DNA sequence >SLH222 (SLH222Q) /CSM/SL/SLH2-A/SLH222Q.Seq.d/ XXXXX...603Q.Seq.d/ 728 0.0 SLI537 (SLI537Q) /CSM/SL/SLI5-B/SLI537Q.Seq.d/ 728 0.0 SLH222 (SLH222Q) /CSM/SL/SLH2

Dicty_cDB: SLH241 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH241 (Link to dictyBase) - - - Contig-U15835-1 SLH241E (Link... to Original site) - - - - - - SLH241E 371 Show SLH241 Library SL (Link to library) Clone ID SLH241 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-B/SLH241Q.Seq.d/ Representative seq. ID SLH24...1E (Link to Original site) Representative DNA sequence >SLH241 (SLH241Q) /CSM/SL/SLH2-B/SLH241Q.Seq.d/ GAAGT....Seq.d/ 638 0.0 VFE160 (VFE160Q) /CSM/VF/VFE1-C/VFE160Q.Seq.d/ 638 0.0 SLH241 (SLH241Q) /CSM/SL/SLH2-B/SLH24

Dicty_cDB: SLH278 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH278 (Link to dictyBase) - - - Contig-U16382-1 SLH278Z (Link... to Original site) - - SLH278Z 528 - - - - Show SLH278 Library SL (Link to library) Clone ID SLH278 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-D/SLH278Q.Seq.d/ Representative seq. ID SLH27...8Z (Link to Original site) Representative DNA sequence >SLH278 (SLH278Q) /CSM/SL/SLH2-D/SLH278Q.Seq.d/ XXXXX...75 (SLH375Q) /CSM/SL/SLH3-D/SLH375Q.Seq.d/ 1047 0.0 SLH278 (SLH278Q) /CSM/SL/SLH2-D/SLH278Q.Seq.d/ 1047 0.0

Dicty_cDB: SLH221 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLH221 (Link to dictyBase) - - - Contig-U16381-1 SLH221Z (Link... to Original site) - - SLH221Z 595 - - - - Show SLH221 Library SL (Link to library) Clone ID SLH221 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLH2-A/SLH221Q.Seq.d/ Representative seq. ID SLH22...1Z (Link to Original site) Representative DNA sequence >SLH221 (SLH221Q) /CSM/SL/SLH2-A/SLH221Q.Seq.d/ XXXXX...LH722 (SLH722Q) /CSM/SL/SLH7-A/SLH722Q.Seq.d/ 559 e-158 SLH221 (SLH221Q) /CSM/SL/SLH2-A/SLH221Q.Seq.d/ 559 e

Dicty_cDB: SSF460 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SS (Link to library) SSF460 (Link to dictyBase) - - - Contig-U03803-1 SSF460Z (Link... to Original site) - - SSF460Z 453 - - - - Show SSF460 Library SS (Link to library) Clone ID SSF460 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSF4-C/SSF460Q.Seq.d/ Representative seq. ID SSF46...0Z (Link to Original site) Representative DNA sequence >SSF460 (SSF460Q) /CSM/SS/SSF4-C/SSF460Q.Seq.d/ XXXXX...s) Value SSM309 (SSM309Q) /CSM/SS/SSM3-A/SSM309Q.Seq.d/ 424 e-118 SSH196 (SSH196Q) /CSM/SS/SSH1-D/SSH196Q.Seq.d/ 424 e-118 SSF4

Dicty_cDB: SLC485 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC485 (Link to dictyBase) - - - Contig-U16358-1 SLC485Z (Link... to Original site) - - SLC485Z 452 - - - - Show SLC485 Library SL (Link to library) Clone ID SLC485 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-D/SLC485Q.Seq.d/ Representative seq. ID SLC48...5Z (Link to Original site) Representative DNA sequence >SLC485 (SLC485Q) /CSM/SL/SLC4-D/SLC485Q.Seq.d/ XXXXX... 825 0.0 SLG820 (SLG820Q) /CSM/SL/SLG8-A/SLG820Q.Seq.d/ 825 0.0 SLC485 (SLC485Q) /CSM/SL/SLC4-D/SLC4

Dicty_cDB: SLC486 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC486 (Link to dictyBase) - - - Contig-U16480-1 SLC486E (Link... to Original site) - - - - - - SLC486E 451 Show SLC486 Library SL (Link to library) Clone ID SLC486 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-D/SLC486Q.Seq.d/ Representative seq. ID SLC48...6E (Link to Original site) Representative DNA sequence >SLC486 (SLC486Q) /CSM/SL/SLC4-D/SLC486Q.Seq.d/ GTCAT...7Q.Seq.d/ 868 0.0 SLD427 (SLD427Q) /CSM/SL/SLD4-B/SLD427Q.Seq.d/ 868 0.0 SLC486 (SLC486Q) /CSM/SL/SLC4-D/SLC4

Dicty_cDB: SLC436 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC436 (Link to dictyBase) - - - Contig-U16460-1 SLC436Z (Link... to Original site) - - SLC436Z 344 - - - - Show SLC436 Library SL (Link to library) Clone ID SLC436 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-B/SLC436Q.Seq.d/ Representative seq. ID SLC43...6Z (Link to Original site) Representative DNA sequence >SLC436 (SLC436Q) /CSM/SL/SLC4-B/SLC436Q.Seq.d/ XXXXX.../CSM/SL/SLE2-C/SLE258Q.Seq.d/ 470 e-132 SLC773 (SLC773Q) /CSM/SL/SLC7-D/SLC773Q.Seq.d/ 470 e-132 SLC4

Dicty_cDB: SLC403 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC403 (Link to dictyBase) - - - Contig-U16252-1 SLC403Z (Link... to Original site) - - SLC403Z 492 - - - - Show SLC403 Library SL (Link to library) Clone ID SLC403 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-A/SLC403Q.Seq.d/ Representative seq. ID SLC40...3Z (Link to Original site) Representative DNA sequence >SLC403 (SLC403Q) /CSM/SL/SLC4-A/SLC403Q.Seq.d/ XXXXX...-B/SLE731Q.Seq.d/ 902 0.0 SLC403 (SLC403Q) /CSM/SL/SLC4-A/SLC403Q.Seq.d/ 902 0.0 SLC241 (SLC241Q) /CSM/SL/SL

Dicty_cDB: SLC409 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC409 (Link to dictyBase) - - - Contig-U14931-1 SLC409Z (Link... to Original site) - - SLC409Z 483 - - - - Show SLC409 Library SL (Link to library) Clone ID SLC409 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-A/SLC409Q.Seq.d/ Representative seq. ID SLC40...9Z (Link to Original site) Representative DNA sequence >SLC409 (SLC409Q) /CSM/SL/SLC4-A/SLC409Q.Seq.d/ XXXXX... SLH501 (SLH501Q) /CSM/SL/SLH5-A/SLH501Q.Seq.d/ 858 0.0 SLF191 (SLF191Q) /CSM/SL/SLF1-D/SLF191Q.Seq.d/ 858 0.0 SLC409 (SLC4

Dicty_cDB: SLC470 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC470 (Link to dictyBase) - - - Contig-U15735-1 SLC470Z (Link... to Original site) - - SLC470Z 386 - - - - Show SLC470 Library SL (Link to library) Clone ID SLC470 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-C/SLC470Q.Seq.d/ Representative seq. ID SLC47...0Z (Link to Original site) Representative DNA sequence >SLC470 (SLC470Q) /CSM/SL/SLC4-C/SLC470Q.Seq.d/ XXXXX...Seq.d/ 533 e-151 SLF229 (SLF229Q) /CSM/SL/SLF2-B/SLF229Q.Seq.d/ 533 e-151 SLC470 (SLC470Q) /CSM/SL/SLC4-C/SLC4

Dicty_cDB: SLC487 [Dicty_cDB

Lifescience Database Archive (English)

Full Text Available SL (Link to library) SLC487 (Link to dictyBase) - - - Contig-U12865-1 SLC487Z (Link... to Original site) - - SLC487Z 404 - - - - Show SLC487 Library SL (Link to library) Clone ID SLC487 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC4-D/SLC487Q.Seq.d/ Representative seq. ID SLC48...7Z (Link to Original site) Representative DNA sequence >SLC487 (SLC487Q) /CSM/SL/SLC4-D/SLC487Q.Seq.d/ XXXXX...1 0.0 SSF377 (SSF377Q) /CSM/SS/SSF3-D/SSF377Q.Seq.d/ 801 0.0 SLC492 (SLC492Q) /CSM/SL/SLC4-D/SLC4

Developing a conceptual model for the internal data source to measure customer satisfaction

OpenAIRE

Al-Mutawa, T; Eldabi, T; Brinkman, WP

2006-01-01

Traditional CSM approach is performed at certain frequencies. The gap between such events can be termed as a ‘blind period’, because customer satisfaction is left unobserved and unmanaged. The blind period may sometimes accelerate the growth of customer dissatisfaction. One way to eliminate the impact of the blind period is to reduce the gap between CSM events. The initial assessment indicates that conducting CSM more frequently, may weaken the accuracy of measurement, and increase the cost o...

Contrôleur Régional (h/f) | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

En collaboration avec la Division des ressources humaines, administrer, mettre en œuvre et évaluer des règlements administratifs, des systèmes, des contrôles et des services reliés à tous les aspects de la gestion des ressources humaines au bureau régional, ce qui comprend le recrutement, la classification et la ...

Résultats de recherche | Page 53 | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

Corruption, opportunités économiques et concurrence. Published date. 1 janvier 2012. Études ... Mouvements sociaux dans le contexte de conflits armés : causes et effets de la défense des droits humains (1980-2012). La place de plus en plus prépondérante qui occupe la défense des droits humains dans les ...

Detailed evaluation of two phase natural circulation flow in the cooling channel of the ex-vessel core catcher for EU-APR1400

Energy Technology Data Exchange (ETDEWEB)

Park, Rae-Joon, E-mail: rjpark@kaeri.re.kr; Ha, Kwang-Soon; Rhee, Bo-Wook; Kim, Hwan Yeol

2016-03-15

Highlights: • Ex-vessel core catcher of PECS is installed in EU-APR1400. • CE-PECS has been conducted to test a cooling capability of the PECS. • Two phase flow in CE-PECS and PECS was analyzed using RELAP5/MOD3. • RELAP5 results are very similar to the CE-PECS data. • The super-step design is suitable for steam injection into the downcomer in PECS. - Abstract: The ex-vessel core catcher of the PECS (Passive Ex-vessel corium retaining and Cooling System) is installed to retain and cool down the corium in the reactor cavity of the EU (European Union)-APR (Advanced Power Reactor) 1400. A verification experiment on the cooling capability of the PECS has been conducted in the CE (Cooling Experiment)-PECS. Simulations of a two-phase natural circulation flow using the RELAP5/MOD3 computer code in the CE-PECS and PECS have been conducted to predict the two-phase flow characteristics, to determine the natural circulation mass flow rate in the cooling channel, and to evaluate the scaling in the experimental design of the CE-PECS. Particularly from a comparative study of the prototype PECS and the scaled test facility of the CE-PECS, the orifice loss coefficient in the CE-PECS was found to be 6 to maintain the coolant circulation mass flux, which is approximately 273.1 kg/m{sup 2} s. The RELAP5 results on the coolant circulation mass flow rate are very similar to the CE-PECS experimental results. An increase in the coolant injection temperature and the heat flux lead to an increase in the coolant circulation mass flow rate. In the base case simulation, a lot of vapor was injected into the downcomer, which leads to an instability of the two-phase natural circulation flow. A super-step design at a downcomer inlet is suitable to prevent vapor injection into the downcomer piping.

Detailed evaluation of two phase natural circulation flow in the cooling channel of the ex-vessel core catcher for EU-APR1400

International Nuclear Information System (INIS)

Park, Rae-Joon; Ha, Kwang-Soon; Rhee, Bo-Wook; Kim, Hwan Yeol

2016-01-01

Highlights: • Ex-vessel core catcher of PECS is installed in EU-APR1400. • CE-PECS has been conducted to test a cooling capability of the PECS. • Two phase flow in CE-PECS and PECS was analyzed using RELAP5/MOD3. • RELAP5 results are very similar to the CE-PECS data. • The super-step design is suitable for steam injection into the downcomer in PECS. - Abstract: The ex-vessel core catcher of the PECS (Passive Ex-vessel corium retaining and Cooling System) is installed to retain and cool down the corium in the reactor cavity of the EU (European Union)-APR (Advanced Power Reactor) 1400. A verification experiment on the cooling capability of the PECS has been conducted in the CE (Cooling Experiment)-PECS. Simulations of a two-phase natural circulation flow using the RELAP5/MOD3 computer code in the CE-PECS and PECS have been conducted to predict the two-phase flow characteristics, to determine the natural circulation mass flow rate in the cooling channel, and to evaluate the scaling in the experimental design of the CE-PECS. Particularly from a comparative study of the prototype PECS and the scaled test facility of the CE-PECS, the orifice loss coefficient in the CE-PECS was found to be 6 to maintain the coolant circulation mass flux, which is approximately 273.1 kg/m"2 s. The RELAP5 results on the coolant circulation mass flow rate are very similar to the CE-PECS experimental results. An increase in the coolant injection temperature and the heat flux lead to an increase in the coolant circulation mass flow rate. In the base case simulation, a lot of vapor was injected into the downcomer, which leads to an instability of the two-phase natural circulation flow. A super-step design at a downcomer inlet is suitable to prevent vapor injection into the downcomer piping.

Study of cover source mismatch in steganalysis and ways to mitigate its impact

Science.gov (United States)

Kodovský, Jan; Sedighi, Vahid; Fridrich, Jessica

2014-02-01

When a steganalysis detector trained on one cover source is applied to images from a different source, generally the detection error increases due to the mismatch between both sources. In steganography, this situation is recognized as the so-called cover source mismatch (CSM). The drop in detection accuracy depends on many factors, including the properties of both sources, the detector construction, the feature space used to represent the covers, and the steganographic algorithm. Although well recognized as the single most important factor negatively affecting the performance of steganalyzers in practice, the CSM received surprisingly little attention from researchers. One of the reasons for this is the diversity with which the CSM can manifest. On a series of experiments in the spatial and JPEG domains, we refute some of the common misconceptions that the severity of the CSM is tied to the feature dimensionality or their "fragility." The CSM impact on detection appears too difficult to predict due to the effect of complex dependencies among the features. We also investigate ways to mitigate the negative effect of the CSM using simple measures, such as by enlarging the diversity of the training set (training on a mixture of sources) and by employing a bank of detectors trained on multiple different sources and testing on a detector trained on the closest source.

The Origin and Evolution of the Infrared Light Curve of SN2010jl

Science.gov (United States)

Dwek, Eli; Sarangi, Arkaprabha; Arendt, Richard; Fox, Ori; Kallman, Timothy; Kazanas, Demosthenes

2018-01-01

SN2010jl is a luminous core-collapse supernova (CCSN) of Type IIn that is surrounded by a dense circumstellar medium (CSM). The supernova (SN) luminosity vastly exceeds the available power from radiactive elements in the ejecta, and is powered by the interaction of the SN shock wave with the ambient medium. Upper limits on the UV and near-IR (NIR) emission from pre-explosion images of the region suggest that any progenitor star was hidden by pre-existing CSM dust. After day ~80, the SN spectrum shows the development of an IR excess above the extrapolated UVO emission arising from the shocked CSM. This IR component is attributed to thermal emission from dust.After day ~300, the light curve exhibits a rise in the NIR luminosity, concurrent with a steep decline at UVO wavelengths. Ruling out any possible contribution of SN-condensed dust to the IR light curve, we show that the early IR emission arises from the pre-existing CSM dust that survived the flash of radiation from the shock breakout. The late IR emission arises from newly-formed CSM dust that condensed in the cooling dust-free postshock gas of the advancing SN shock wave. Our analysis presents the first detailed modeling of dust formation in a cooling postshock environment, and provides important insights into the interaction of the SN shock wave with the CSM.

The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.

Science.gov (United States)

Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

2016-01-01

The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Japānas un Amerikas Savienoto Valstu kauja par Okinavu 1945. gada: 1.aprīlis – 22. jūnijs

OpenAIRE

Leimanis, Normunds

2017-01-01

Bakalaura darba tēmas nosaukums ir „Japānas un Amerikas Savienoto Valstu kauja par Okinavu 1945. gada: 1. aprīlis – 22. jūnijs ”. Tā ir viena no lielākajām un asiņainākajām kaujām, kura notika Otrā Pasaules kara laika beigās. Tā bija viena no pēdējām kaujām Otrā Pasaules kara laikā. Kaujā par Okinavu piedalijās amerikāņu un japāņu karaspēki, kas cīnījās par savu valsti un tās godu. Galvenie Okinavas kaujas dalībnieki bija japāņu 32. armija un amerikāņu 10.armija. Galvenais atbildīgais par ...

Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

Energy Technology Data Exchange (ETDEWEB)

Kim, Ki-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices.

Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

International Nuclear Information System (INIS)

Kim, Ki-Hwan

2016-01-01

Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices

Réutilisation d'argiles très plastiques (A4) en remblai : Suivi du comportement après trois ans de réalisation

OpenAIRE

BERCHE, Véronique; ROBERT, Nicolas; BOUSSAFIR, Yasmina; FERBER, Valéry

2013-01-01

Cet article présente la réalisation de remblais en argile très plastiques en 2003 sur l'A34 dans les Ardennes (France) ainsi que les résultats du suivi du comportement de ces remblais dans le temps. Après un bref rappel des conditions de réalisation de ces remblais, un résumé des résultats de portance et de densité à court et moyen terme sera exposé. Dans un deuxième temps, des résultats de densité (double sonde Gamma et passage au banc Gamma) et essais Dynaplaque réalisés en 2006 seront c...

Evaluasi penggunaan tepung cangkang rajungan sebagai bahan baku pakan juwana udang windu Penaeus monodon

Directory of Open Access Journals (Sweden)

Agus Kurnia

2016-12-01

Full Text Available ABSTRACT Feeding trial was conducted to determine the optimum dietary level of the crab shell meal (CSM for replacement of fish meal (FM for growth and survival rate of black tiger shrimp larvae. The shrimp (initial weight: 0,0134±0,02 g were fed with six experimental diet for six weeks which were formulated to replace FM protein by with CSM at various substitution levels: diet A (0% CSM substitution level, diet B (25% CSM substitution level, diet C (50% CSM substitution level, diet D (75% CSM substitution level, diet E (100% CSM substitution level, diet F (commercial diet. Results from the feeding trial indicates that the shrimp fed with all treatment diet were not significantly different in weight gain and FCR. However, survival rate on the shrimp fed with diet F was significantly different to the other groups. The present study conclude that CSM could be used as protein ingredient in the diet of monodon shrimp juvenile. Keywords: replacement, crabs shell meal, fish meal, black tiger shrimp, survival rate  ABSTRAK Penelitian pakan dilakukan untuk menentukan dosis optimum tepung cangkang rajungan (TCR untuk mengganti tepung ikan (TI dalam pakan terhadap pertumbuhan dan kelangsungan hidup larva udang windu. Udang windu (berat awal: 0,00134±0,02 g diberi pakan uji selama enam minggu yang diformulasi untuk mengganti TI dengan tingkat persentasi penggantian TCR dengan desain formulasi pakan A (0% substitusi TCR, pakan B (25% substitusi TCR, pakan C (50% substitusi TCR, pakan D (75% substitusi TCR, pakan E (100% substitusi TCR, dan pakan F (pakan komersial sebagai pakan kontrol. Hasil dari penelitian ini menunjukkan bahwa udang yang diberi pakan untuk semua perlakuan tidak memberikan pengaruh nyata terhadap pertumbuhan dan laju pertumbuhan harian. Akan tetapi kelompok udang yang diberi pakan F berpengaruh nyata terhadap kelangsungan hidup dibanding dengan perlakuan lainnya. Hasil penelitian ini menyimpulkan bahwa tepung cangkang rajungan

Dicty_cDB: FC-BR23 [Dicty_cDB

Lifescience Database Archive (English)

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Dicty_cDB: SLH285 [Dicty_cDB

Lifescience Database Archive (English)

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Dicty_cDB: SLC441 [Dicty_cDB

Lifescience Database Archive (English)

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Dicty_cDB: SLC489 [Dicty_cDB

Lifescience Database Archive (English)

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First regional CSM program planned.

Science.gov (United States)

1982-09-01

6 countries in the English-speaking Caribbean (Antigua, Barbados, Dominica, St. Kitts/Nevis, St. Lucia, and St. Vincent) are scheduled to form the 1st regional contraceptive social marketing program. The program will be under the auspices of the Barbados Family Planning Association. By combining resources, contraceptive social marketing should be able to effectively augment family planning activities in smaller countries where individual programs wuld be too costly. The regional program will also determine whether program elements from 1 country in a region are relevant in other countries. The Caribbean region as a whole has experienced a general decline in both crude birth rates and fertility rates during the past 15 years; however, adolescent fertility rates remain high and an average of 46% of the populations of Caribbean countries are under 15 years of age. Although heavy emigration has traditionally curbed population increases, new restrictive immigration laws are expected. Further increases in the working age population will contribute to already high unemployment rates and hinder economic development. The 6 countries selected for the social marketing program are receptive to innovative family planning approaches and have the basic marketing infrastructure required. Community-based distribution programs already in operation in these countries distribute condoms, oral contraceptives, and barrier methods. The success of these programs has plateaued, and there is a need for delivery systems capable of reaching broader segments of the population. The social marketing program will be phased in to ensure local acceptance among national leaders and consumers. The regional program hopes to borrow elements from Jamaica's contraceptive social marketing program to avoid the costs involved in starting a program from scratch. A major innovation will be the use of mass media advertising for contraceptives.

CSM a success in Bangladesh.

Science.gov (United States)

1983-01-01

The Bangladesh Social Marketing Project (SMP), providing contraceptives at an annual rate of 931,000 couple years of protection (CYP) as of June 1983, is a success. This figure has grown markedly since the start of the program in late 1975, when the SMP provided 80,000 CYPs, or 8% of nonclinical protection provided. The SMP has contributed to the steadily increasing national nonclinical contraceptive distribution. Currently, SMP distribution accounts for as much as the government and nongovernment programs combined. When clinical methods (including sterilizations) are added to national distribution, the SMP share represents about 28% of total contraceptive use. The SMP does not provide clinical methods, but the entire increase in nonclinical protection provided by the national program since 1975 has been the result of SMP product sales. The SMP utilizes the available mass media for promotion, including print, radio, television, as well as outdoor media and point of purchase materials. Mobile Film Units (MFUs) are an innovative promotional method employed by the SMP. Approximately 80 night time outdoor showings are organized each month in rural areas by SMP promoters. Typically, several short films, usually a popular story with a family planning theme, are run. Between each film the SMP products are of advertised. Products are often sold during and after the films. Retail outlets for SMP products include general stores, pharmacies, and other small shops. When products were introduced in 1975 retail outlets totaled 7500. By August 1983 the number of country wide retailers carrying SMP products had grown to nearly 100,000. In 1982 a marketing strategy emphasizing the role of doctors and rural medical practitioners (RMPs) was introduced. There are between 70,00-100,000 RMPs in Bangladesh. They are well known and respected "doctors" in their villages and add an extensive family planning outreach to the SMP system. The most important advantage of using the RMPs is their personal contact with OC users. Since October 1981 the SMP has detailed approximately 30,000 RMPs; 15,000 have attended conferences and 6600 have purchased OCs. Consumers targeted by the SMP have annual incomes ranging from US$200-$400. A well defined organizational system has evolved that delineates the roles of government, the contractor, and the project personnel regarding specific policy, enterprise, management, and operational functions. The project staff of nearly 300 includes managers for the sales, development, marketing, and finance and administration departments.

Entre culture générale et enjeux des métiers d'ingénieur : la diversité des enseignements en sciences humaines et sociales à l'École Centrale de Lyon

Directory of Open Access Journals (Sweden)

Hourcade Nicolas

2014-01-01

Full Text Available Ce texte analyse le développement d'enseignements en sciences humaines et sociales à l'École Centrale de Lyon, établissement formant des ingénieurs généralistes. Très limités au milieu des années 1990, les cours de SHS constituent aujourd'hui un aspect significatif de la formation. La première spécificité de cette offre pédagogique est de comprendre un nombre relativement important de cours obligatoires, complétés par des activités optionnelles. Sa seconde particularité est de traiter de thématiques générales à côté de contenus classiques liés aux enjeux des métiers d'ingénieur. Sa troisième caractéristique est de s'appuyer sur une implication de l'équipe SHS dans les activités professionnalisantes, tout en les séparant des enseignements disciplinaires. Enfin, l'inscription des SHS à l'ECL s'effectue plus par l'enseignement que par la recherche, chaque membre de l'équipe étant rattaché à un laboratoire extérieur différent.

Suivi après le traitement du cancer du sein

Science.gov (United States)

Sisler, Jeffrey; Chaput, Geneviève; Sussman, Jonathan; Ozokwelu, Emmanuel

2016-01-01

Résumé Objectif Offrir aux médecins de famille un résumé des recommandations fondées sur les données probantes pour guider les soins aux survivantes traitées pour le cancer du sein. Qualité des données Une recherche documentaire a été effectuée dans MEDLINE entre 2000 et 2016 à l’aide des mots-clés anglais suivants : breast cancer, survivorship, follow-up care, aftercare, guidelines et survivorship care plans, en se concentrant sur la revue des lignes directrices publiées récemment par les organismes nationaux de cancérologie. Les données étaient de niveaux I à III. Message principal Les soins aux survivantes comportent 4 facettes : surveillance et dépistage, prise en charge des effets à long terme, promotion de la santé et coordination des soins. La surveillance des récidives ne se traduit que par une mammographie annuelle, et le dépistage d’autres cancers doit suivre les lignes directrices basées sur la population. La prise en charge des effets à long terme du cancer et de son traitement aborde des problèmes courants tels la douleur, la fatigue, le lymphœdème, la détresse et les effets indésirables des médicaments, de même que les préoccupations à long terme comme la santé du cœur et des os. La promotion de la santé met en relief les bienfaits de l’activité chez les survivantes du cancer, avec l’accent mis sur l’activité physique. Les soins aux survivantes sont de meilleure qualité lorsque divers services et professionnels de la santé participent aux soins, et le médecin de famille joue un rôle important dans la coordination des soins. Conclusion Les médecins de famille sont de plus en plus souvent les principaux fournisseurs de soins de suivi après le traitement du cancer du sein. Le cancer du sein doit être considéré comme une affection médicale chronique, même chez les femmes en rémission, et les patientes profitent de la même approche que celle utilisée pour les autres affections chroniques en

Onset of liquid droplet entrainment on a direct vessel injection system for APR1400

Energy Technology Data Exchange (ETDEWEB)

Kim, Han-sol; Lee, Jae-Young [Handong Global University, Pohang (Korea, Republic of); Kim, Jong-Rok; Euh, Dong-Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2016-10-15

In this research, a series of visualization works was conducted to understand droplet entrainment of the flow pattern generated in direct vessel injection system(DVI) of Korea nuclear power plant, APR 1400. In the emergency situation of a nuclear power plant, reliability of DVI cooling can be an important issue. It is known that, the amount and the rate of entrainment during the DVI cooling process can significantly affect the total heat removal. To visualize the film Reynolds number closely related with onset of droplet entrainment induced by falling film flow and lateral air flow in a small gap, confocal chromatic sensing method for measuring accurately film thickness and depth averaging particle image velocimetry for film velocity were used. The results have been post processed 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. To visualize the droplet entrainment induced by falling film flow and lateral air flow in a small gap, shadowgraph method with CCD camera (2200fps, 1280 pixel X 800 pixel, ) on coated plate with super water-repellent agent was used. The results have been post processed using 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. By adopting both super hydrophobic coating method and shadowgraph method, entrainment in a narrow gap was successfully visualized that has rarely performed before and meaningful results for DVI system research fields have been made.

Onset of liquid droplet entrainment on a direct vessel injection system for APR1400

International Nuclear Information System (INIS)

Kim, Han-sol; Lee, Jae-Young; Kim, Jong-Rok; Euh, Dong-Jin

2016-01-01

In this research, a series of visualization works was conducted to understand droplet entrainment of the flow pattern generated in direct vessel injection system(DVI) of Korea nuclear power plant, APR 1400. In the emergency situation of a nuclear power plant, reliability of DVI cooling can be an important issue. It is known that, the amount and the rate of entrainment during the DVI cooling process can significantly affect the total heat removal. To visualize the film Reynolds number closely related with onset of droplet entrainment induced by falling film flow and lateral air flow in a small gap, confocal chromatic sensing method for measuring accurately film thickness and depth averaging particle image velocimetry for film velocity were used. The results have been post processed 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. To visualize the droplet entrainment induced by falling film flow and lateral air flow in a small gap, shadowgraph method with CCD camera (2200fps, 1280 pixel X 800 pixel, ) on coated plate with super water-repellent agent was used. The results have been post processed using 4G Insight software. By measuring two dimensional film Reynolds number, we can predict the onset of droplet entrainment and obtain visible breakup region intuitively. By adopting both super hydrophobic coating method and shadowgraph method, entrainment in a narrow gap was successfully visualized that has rarely performed before and meaningful results for DVI system research fields have been made

Detection of sequential activation of left atrium and coronary sinus musculature in the general population

Directory of Open Access Journals (Sweden)

Masaki Ota, MD

2016-12-01

Conclusions: Far-field LA potentials are often recorded in the CS during sequential LA and CSM activation in the general population. The timing of LA potentials in CS recordings reflected the direction of conduction across the CSM.

THE FLOODS FROM JUNE-JULY 2010 ON THE RIVERS FROM THE SUCEAVA HYDROGRAPHIC BASIN

Directory of Open Access Journals (Sweden)

ADRIANA MIHAELA PORCUŢAN

2014-10-01

Full Text Available Le bassin hydrographique asymétrique de Suceava, avec une surface de 2612 km2, est situé dans le nord de la Roumanie, mais il se propage également sur le territoire ukrainien, jusqu'à 47 o 58' N. Ce bassin hydrographique comprend deux grandes unités de secours avec des caractéristiques géographiques distinctes (montagneuse et plateau, séparés par une zone de transition représenté par un secteur de piemont et une succession de dépressions. L'analyse des crues a été faite en utilisant les données de 8 stations hydrologiques qui surveillent les inondations du cours principal (3 et des affluents les plus importants de la rivière (5. Après avoir analysé les facteurs naturels et humains qui ont produit le inondations de Juin - July 2010, on a déterminé l'espace des ondes de crue, l'heure et paramètres hydriques des cours d'eau surveillés, et à la fin il a évalué l'environnement, les risques sociaux et économiques déterminées par ces inondations.

ACADEMIE NATIONALE DE MEDECINE - UNE TRADITION BICENTENAIRE DE MODERNITE

Directory of Open Access Journals (Sweden)

Claude JAFFIOL

2017-05-01

Full Text Available EXTRACTC'est sous le signe de la modernité, qu’est fondée l'Académie nationale de médecine, au début du XIXème siècle, alors que notre discipline émerge d'une longue période d'obscurantisme.Après Bichat, mort prématurément, les pionniers, Laënnec, dont le stéthoscope permet pour la première fois d'écouter ce qui se passe à l'intérieur du corps humain ,  Larrey, le premier chirurgien des temps modernes , Pinel, le premier psychiatre... sont appelés  à siéger dans la jeune académie fondée par Louis XVIII en 1820.Toujours sous le signe de la modernité, c'est à l'Académie de médecine que présentent leurs travaux révolutionnaires Pasteur et Marie Curie, deux figures emblématiques de la science, des découvreurs comme Laveran, prix Nobel de médecine, des novateurs comme Robert Debré, pédiatre éminent mais aussi inventeur des CHU. Alexander Fleming y fit connaître au monde sa découverte de la pénicilline.

Effect of feeding cottonseed meal on some hematological and serum biochemical parameters in broiler birds

Directory of Open Access Journals (Sweden)

G. Thirumalaisamy

2016-07-01

Full Text Available Aim: The study was undertaken to find out the effect of feeding cottonseed meal (CSM on performance of hematological and serum biochemical parameters in broiler birds. Materials and Methods: A 6-week biological trial was carried out with 432-day-old Cobb 400 broiler chicks distributed to nine experimental diets with six replicates, each containing eight chicks. The experimental diets were formulated based on total amino acids (BTAA or based on digestible amino acids (BDAA with or without iron supplementation with two levels of CSM (2% and 4% and control diet based on maize – soybean. The whole blood was subjected to hematological studies. The serum samples were analyzed for protein fractions and lipid profiles. Results: The packed cell volume (PCV value, red blood cell (RBC numbers, and hemoglobin (Hb were lower in iron unsupplemented CSM BTAA or BDAA diets than the control (33.86-35.54 vs. 36.41%, 2.78-2.87 vs. 2.98 × 106/μl, and 10.30-10.70 vs. 10.88%. Supplementation of iron in CSM diets improved the PCV, RBC numbers, and Hb, and the values were comparable to the control. White blood cell numbers, mean corpuscular volume, mean corpuscular Hb (MCH, and MCH concentration values were comparable to the control. The erythrocyte osmotic fragility (EOF was poor in birds fed diets containing up to 4% CSM BTAA or CSM BDAA without iron supplementation (32.02-32.57 vs. 28.77%. Supplementation of iron improved the EOF. The serum cholesterol level did not change with or without iron supplementation. Conclusion: This study suggested that feeding of CSM BTAA or BDAA up to 4% level voiding iron supplementation lowers the hematological parameters, whereas supplementation of iron did not alter serum protein fractions and cholesterol profile; however, it had lowered some hematological parameters, which was rectified by iron supplementation.

Balance of Autonomic Nervous System Predicts Who Benefits from a Self-management Intervention Program for Irritable Bowel Syndrome.

Science.gov (United States)

Jarrett, Monica E; Cain, Kevin C; Barney, Pamela G; Burr, Robert L; Naliboff, Bruce D; Shulman, Robert; Zia, Jasmine; Heitkemper, Margaret M

2016-01-31

To determine if potential biomarkers can be used to identify subgroups of people with irritable bowel syndrome (IBS) who will benefit the most or the least from a comprehensive self-management (CSM) intervention. In a two-armed randomized controlled trial a CSM (n = 46) was compared to a usual care (n = 46) group with follow-up at 3 and 6 months post randomization. Biomarkers obtained at baseline included heart rate variability, salivary cortisol, interleukin-10 produced by unstimulated peripheral blood mononuclear cells, and lactulose/mannitol ratio. Linear mixed models were used to test whether these biomarkers predicted improvements in the primary outcomes including daily abdominal pain, Gastrointestinal Symptom score and IBS-specific quality of life. The nurse-delivered 8-session CSM intervention is more effective than usual care in reducing abdominal pain, reducing Gastrointestinal Symptom score, and enhancing quality of life. Participants with lower nighttime high frequency heart rate variability (vagal modulation) and increased low frequency/high frequency ratio (sympathovagal balance) had less benefit from CSM on abdominal pain. Salivary cortisol, IL-10, and lactulose/mannitol ratio were not statistically significant in predicting CSM benefit. Baseline symptom severity interacts with treatment, namely the benefit of CSM is greater in those with higher baseline symptoms. Cognitively-focused therapies may be less effective in reducing abdominal pain in IBS patients with higher sympathetic tone. Whether this a centrally-mediated patient characteristic or related to heightened arousal remains to be determined.

The influence of irradiation treatment on gossypol and protein digestibility of decorticated cottonseed meal for Broiler chicks

International Nuclear Information System (INIS)

Farag, M.D.H.

2000-01-01

The Effect of gamma irradiation (5-20 kGy) on the chemical composition, soluble protein, available lysine, gossypol, in-vitro and in vivo digestibility of decorticated cottonseed meal (CSM) and the performance of broilers fed processed CSM were investigated. Radiation treatment of CSM at dose levels of 5, 10, 15 and 20 kGy did not affect moisture, crude protein, ether extract, crude fiber, ash and NFW content. However, the treatment reduced soluble protein by 4.18, 7.82, 10.91, 13.46%, respectively. Fluorodinitrobenzene-available lysine concentration reduced by 4.48, 8.12, 17.65 and 21.29% respectively. The concentrations of total gossypol decreased by 7.97, 15.78, 19.92 and 25.39% and free gossypol by 3.74, 7.85, 18.43 and 28.01%, respectively. The digestibility of CSM protein was increased by 5.3, 9.0, 16.6 and 17.2%, for in-vitro digestibility and by 4.8, 7.3, 9.4 and 12.9% for in-vivo due to treatment with 5,10, 15 and 20 kGy, respectively. From 7 to 42 days, arbor acres broilers were freely given iso energetic and iso nitrogenous : corn-soy control diet or diets containing 300 g kg -1 raw or irradiated CSM at 4, 15 or 20 kGy. Intake of raw CSM affected growth, feed intake and feed conversion as compared with birds receiving the control diet

Language mapping using high gamma electrocorticography, fMRI, and TMS versus electrocortical stimulation.

Science.gov (United States)

Babajani-Feremi, Abbas; Narayana, Shalini; Rezaie, Roozbeh; Choudhri, Asim F; Fulton, Stephen P; Boop, Frederick A; Wheless, James W; Papanicolaou, Andrew C

2016-03-01

The aim of the present study was to compare localization of the language cortex using cortical stimulation mapping (CSM), high gamma electrocorticography (hgECoG), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS). Language mapping using CSM, hgECoG, fMRI, and TMS were compared in nine patients with epilepsy. Considering CSM as reference, we compared language mapping approaches based on hgECoG, fMRI, and TMS using their sensitivity, specificity, and the results of receiver operating characteristic (ROC) analyses. Our results show that areas involved in language processing can be identified by hgECoG, fMRI, and TMS. The average sensitivity/specificity of hgECoG, fMRI, and TMS across all patients was 100%/85%, 50%/80%, and 67%/66%, respectively. The average area under the ROC curve of hgECoG, fMRI, and TMS across CSM-positive patients was 0.98, 0.76, and 0.68, respectively. There is considerable concordance between CSM, hgECoG, fMRI, and TMS language mapping. Our results reveal that hgECoG, fMRI, and TMS are valuable tools for presurgical language mapping. Language mapping on the basis of hgECoG, fMRI, and TMS can provide important additional information, therefore, these methods can be used in conjunction with CSM or as an alternative, when the latter is deemed impractical. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Replacing cottonseed meal with ground Prosopis juliflora pods; effect on intake, weight gain and carcass parameters of Afar sheep fed pasture hay basal diet.

Science.gov (United States)

Yasin, Mohammed; Animut, Getachew

2014-08-01

The experiment was conducted to determine the supplementary feeding value of ground Prosopis juliflora pod (Pjp) and cottonseed meal (CSM) and their mixtures on feed intake, body weight gain and carcass parameters of Afar sheep fed a basal diet of pasture hay. Twenty-five yearling fat-tailed Afar rams with mean initial live weight 17.24 ± 1.76 kg (mean ± SD) were used in a randomized complete block design. Animals were blocked on their initial body weight. The experiment was conducted for 12 weeks and carcass evaluation followed. Treatments were hay alone ad libitum (T 1) or with 300 g CSM (T 2), 300 g Pjp (T 5), 2:1 ratio (T 3) and 1:2 ratio of CSM : Pjp (T 4). The CP contents of the hay, CSM and Pjp were 10.5, 44.5 and 16.7 %, respectively. Hay DM intake was higher (P < 0.05) for non-supplemented and total DM intake was lower in non-supplemented. Average daily weight gain (ADG) was lower (P < 0.05) for T 1 compared to all supplemented treatments except T 5. Hot carcass weight and rib-eye muscle area also followed the same trend like that of ADG. Compared with feeding hay alone, supplementing with CSM or a mixture of CSM and Pjp appeared to be a better feeding strategy, biologically, for yearling Afar rams.

Development of the APR1400 model for countercurrent natural circulation in hot leg and steam generator under station blackout

International Nuclear Information System (INIS)

Park, Sang Gil; Kim, Han Chul

2012-01-01

In order to analyze severe accident phenomena, Korea Institute of Nuclear Safety (KINS) made a MELCOR model for APR1400 to examine natural circulation and creep rupture failure in the Reactor Coolant System (RCS) under station blackout (SBO). In this study, we are trying to advance the former model to describe natural circulation more accurately. After Fukushima accident, the concerns of severe accident management, assuring the heat removal capability, has risen for the case when the SBO is happened and there are no more electric powers to cool down decay heat. Under SBO there are three kinds of natural circulation which can delay the core heatup. One is in vessel natural circulation in the upper plenum of reactor vessel and the second is countercurrent natural circulation in hot leg through steam generator tubes and the last is full loop natural circulation when the reactor coolant pump loop seal is cleared and reactor coolant pump sealing is damaged by high temperature and high pressure. Among them this study focuses on the countercurrent natural circulation model using MELCOR1.8.6

Air clearing pressure oscillation produced in a quenching tank by a prototype unit cell sparger of the APR1400

International Nuclear Information System (INIS)

Cho, Seok; Song, Chul-Hwa; Park, Choon-Kyong; Kim, Hwan-Yeol; Baek, Won-Pil

2008-01-01

KAERI has performed a series of experiments to investigate the performance of a prototype sparger for the APR1400 in view of a dynamic load oscillation with a variation of the test conditions such as a discharged air mass, a submergence of the sparger, the valve opening time, and the pool temperature during an air clearing phase. The air mass and pool temperature are in the range of 0.8-1.5 kg and 20-90 o C, respectively. The valve opening time can be adjusted within the range of 0.6-1.8 s. The maximum positive pressure amplitude, which is observed at the bottom of the quenching tank, is increased with the maximum header pressure of the sparger. The valve opening time has a considerable effect on the maximum amplitude. As the opening time decreases, the maximum amplitude at the tank wall is increased. Air mass and pool temperature, however, have a weak effect on the maximum amplitude. Oscillation frequency is decreased with an increase of the air mass in the range of 2.5-4.5 Hz

The incoming global technological and industrial revolution towards competitive sustainable manufacturing

DEFF Research Database (Denmark)

Jovane, F.; Yoshikawa, H.; Alting, Leo

2008-01-01

, knowledge-based, competitive sustainable manufacturing (CSM) has been widely considered as main enabler. This paper presents the necessary steps from economic growth to sustainable development. The reference model for proactive action (RMfPA) is proposed to develop and implement CSM, at national and global...... levels. Furthermore, we also review strategies to pursue CSM at the macro-meso-field level in addition to ongoing national initiatives in different countries and by international organizations. A case study concerning the European Manufuture initiative is cited. The overall results conclude that RMf...

1514-IJBCS-Article-Melima Mamatchi

African Journals Online (AJOL)

KODJIO NORBERT

déterminées dans le sang humain à Gbodjomé (zone de référence) et à Kpémé où les populations consomment des aliments ... Cd et du Pb, qui provoquent un stress oxydatif dans l'organisme humain qui présente une disponibilité à la bioaccumulation de ces ..... reins, le foie, le système nerveux, le sang et peuvent être ...

La Santé: Une Approche Écosystémique

International Development Research Centre (IDRC) Digital Library (Canada)

Le défi consiste à satisfaire les besoins humains sans altérer ni mettre en danger ... L'évolution de cette science a influencé la réflexion de médecins comme le docteur ... Pour les artisans d'une vision globale, l'humain et ses aspirations, son .... coûteux que bien des soins médicaux et des interventions en santé primaire.

Résultats de recherche | Page 137 | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

... Croissance de l'économie et débouchés économiques des femmes 12 Apply ... Les auteurs du Rapport arabe sur le développement humain 2005 mettent en évidence ... à savoir l'abondance de capital humain féminin qualifié dans la région du ... Quinze années de guerre civile et l'instabilité politique et économique qui ...

Strategic Sustainability Management for Enhancing Corporate Value: in the context of Korean Business Circles

NARCIS (Netherlands)

Y-G. Ahn

2007-01-01

textabstractIn line with the growing importance of Corporate Sustainability Management (CSM) in business circles, the linkages between CSM, corporate values and performance is becoming increasingly higher on the agenda both for internal corporate management purposes and for external relations for

Determination of iron absorption and excretion by whole-body counting; Determination de l'absorption et de l'excretion du fer par la methode de comptage global humain

Energy Technology Data Exchange (ETDEWEB)

Hollard, D; Benabid, Y; Berard, M; Bonnin, J; Darnault, J; Millet, M [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1969-07-01

Using a whole-body counter, the authors have studied {sup 59}Fe absorption and loss in 8 normal subjects and in 30 iron deficient patients. Results showed that whole-body counting provided an excellent and simple method for iron retention measurements, obviating many inaccuracies of previous technic. Normal absorption of radio iron with this procedure has ranged from 9 per cent to 20 per cent of the administered tracer in normal subjects, with a mean of 15 per cent. A significant increase in {sup 59}Fe absorption was noted in 21 iron-deficient patients in whom the retention ranged from 40 to 100 per cent. However, 3 iron-deficient patients were found to have low absorption, and their severe iron deficiency could be correlated with this defect in absorption. This method permits also the determination of the rate of iron excretion during the following months and therefore the study of the mechanism of some pathological loss. (authors) [French] L'utilisation de la methode de comptage humain global a permis aux auteurs d'etudier l'absorption et l'excretion du fer-59 chez 8 sujets temoins et 30 sujets hyposideremiques. Les resultats montrent que cette technique simple et directe offre de nombreux avantages sur les methodes employees jusqu'a maintenant pour cette determination. La valeur normale de l'absorption du fer chez les temoins est d'environ 15 pour cent de la dose ingeree. Ce chiffre est tres fortement augmente chez 21 sujets hyposideremiques, pouvant atteindre 100 pour cent de la dose ingeree. Par contre, pour 3 malades, cette absorption est si faible qu'elle suggere une carence par defaut d'absorption. Cette methode permet egalement de suivre l'excretion du fer au cours des mois qui suivent l'examen et de determiner le mecanisme de fuites anormales. (auteurs)

Adverse events after cervical spinal manipulative therapy: consensus based classification and definitions

NARCIS (Netherlands)

Dr. C.P. van der Schans; M. Schmitt; dr. S.E. Lakke; H.A. Kranenburg

2015-01-01

Cervical spinal manipulations (CSM) are frequently employed techniques to alleviate neck pain and headache. Minor and major complications following CSM have been described, though clear consensus on definition and the classification of the complications had not yet been achieved. As a result,

Continuum Level Density in Complex Scaling Method

International Nuclear Information System (INIS)

Suzuki, R.; Myo, T.; Kato, K.

2005-01-01

A new calculational method of continuum level density (CLD) at unbound energies is studied in the complex scaling method (CSM). It is shown that the CLD can be calculated by employing the discretization of continuum states in the CSM without any smoothing technique

Adverse events after cervical spinal manipulative therapy: consensus based classification and definitions

NARCIS (Netherlands)

Kranenburg, Rik; Jorna-Lakke, Sandra; Schmitt, M.A.; van der Schans, Cees

2016-01-01

Cervical spinal manipulations (CSM) are frequently employed techniques to alleviate neck pain and headache. Minor and major complications following CSM have been described, though clear consensus on definition and the classification of the complications had not yet been achieved. As a result,

The Incredibly Long-Lived SN 2005ip

Science.gov (United States)

Fox, Ori

2016-10-01

Type IIn supernovae (SNe IIn) are defined by their relatively narrow spectral line features associated with a dense circumstellar medium (CSM) formed by the progenitor star. The nature of the progenitor and mass loss remains relatively unknown. Shock interaction with the dense CSM can often result in significant UV emission for several years post-explosion, thereby probing the CSM characteristics, progenitor mass loss history and, ultimately, the progenitor itself. The Type IIn SN 2005ip proves to be one of the most interesting and well-studied targets within this subclass. Compared to all other supernovae, SN 2005ip is the most luminous for its age. Now more than 11 years post-explosion, the SN has released >10^51 erg throughout its lifetime as the forward shock continues to collide with a dense CSM. Here we propose HST/STIS-MAMA UV observations of SN 2005ip to investigate the massive CSM. When accounting for the shock travel time, these observations will probe material lost from the progenitor more than 1000 years prior to the explosion. We already have a single HST/STIS spectrum of SN 2005ip from 2014, which was obtained while the shock was still within a higher mass regime. With just 5 orbits, a second spectrum will allow us to directly trace the evolution of the CSM and produce new constraints on the pre-SN mass-loss history. Coinciding with Cycle 24's UV Initiative, this program offers new insight regarding both the progenitor and explosion characteristics of the SN IIn subclass.

Family Access to a Dentist Study (FADS): A Multi-Center Randomized Controlled Trial

Science.gov (United States)

Nelson, Suchitra; Riedy, Christine; Albert, Jeffrey M; Lee, Wonik; Slusar, Mary Beth; Curtan, Shelley; Ferretti, Gerald; Cunha-Cruz, Joana; Milgrom, Peter

2015-01-01

Introduction Many low-income parent/caregivers do not understand the importance of cavity-free primary (baby) teeth and the chronic nature of dental caries (tooth decay). As a consequence, dental preventive and treatment utilization is low even when children are screened in schools and referred for care. This study aims to test a referral letter and Dental Information Guide (DIG) designed using the Common-Sense Model of Self-Regulation (CSM) framework to improve caregivers’ illness perception of dental caries and increase utilization of care by children with restorative dental needs. Methods A multi-site randomized controlled trial with caregivers of Kindergarten to 4th grade children in urban Ohio and rural Washington State will compare five arms: (1) CSM referral letter alone; (2) CSM referral letter + DIG; (3) reduced CSM referral letter alone; (4) reduced CSM referral letter + DIG; (5) standard (control) referral. At baseline, children will be screened at school to determine restorative dental needs. If in need of treatment, caregivers will be randomized to study arms and an intervention packet will be sent home. The primary outcome will be dental care based on a change in oral health status by clinical examination 7 months post-screening (ICDAS sealant codes 1 and 2; restoration codes 3–8; extraction). Enrollment commenced summer 2015 with results in summer 2016. Conclusion This study uses the CSM framework to develop and test behavioral interventions to increase dental utilization among low-income caregivers. If effective this simple intervention has broad applicability in clinical and community-based settings. PMID:26500170

Intake, selection, digesta retention, digestion and gut fill of two coprophageous species, rabbits (Oryctolagus cuniculus) and guinea pigs (Cavia porcellus), on a hay-only diet.

Science.gov (United States)

Franz, R; Kreuzer, M; Hummel, J; Hatt, J-M; Clauss, M

2011-10-01

A colonic separation mechanism (CSM) is the prerequisite for the digestive strategy of coprophagy. Two different CSM are known in small herbivores, the 'wash-back' CSM of lagomorphs and the 'mucous-trap' CSM of rodents. Differences between these groups in their digestive pattern when fed exclusively hay were investigated in six rabbits (Oryctolagus cuniculus) and six guinea pigs (Cavia porcellus). Intake, digestibility (by total faecal collection), solute and particle mean retention times (MRT, using Co-EDTA and Cr-mordanted fibres) were measured. Rabbits selected less fibrous parts of the hay than guinea pigs, leaving orts with higher content of neutral detergent fibre [NDF; 721 ± 21 vs. 642 ± 31 g/kg dry matter (DM) in guinea pigs]. They also expressed a lower NDF digestibility (0.44 ± 0.10 vs. 0.55 ± 0.05 of total), a similar particle MRT (15 ± 3 vs. 18 ± 6 h), a longer solute MRT (51 ± 9 vs. 16 ± 4 h), and a lower calculated dry matter gut fill (19.6 ± 4.7 vs. 29.7 ± 4.1 g DM/kg body mass) than guinea pigs (p bacterial matter from the colonic digesta plug than the 'mucous-trap' CSM found in the guinea pigs. Related to metabolic body mass, rabbits therefore need a less capacious colon for their CSM where a more efficient bacteria wash-out is reflected in the lower fibre digestibility. A lighter digestive tract could contribute to a peculiarity of lagomorphs: their ability to run faster than other similar-sized mammals. © 2010 Blackwell Verlag GmbH.

Surgical Treatment of Cervical Spondylotic Myelopathy Associated Hypertension--A Retrospective Study of 309 Patients.

Directory of Open Access Journals (Sweden)

Ze-qun Li

Full Text Available Hypertension is the most prevalent cardiovascular disease, and various risk factors are known to be involved in it. Cervical spondylotic myelopathy (CSM is the most common non-traumatic cause of myelopathy, which displays neurological symptoms and may induce systemic symptoms. To date, it is still unknown whether CSM is associated with hypertension, and if so, whether the decompression operations can attenuate CSM associated hypertension. Here, a total of 309 patients with CSM who received anterior or posterior decompression surgery were enrolled as subjects. Blood pressure measurements were performed before and within one week after the surgery. Among the 309 subjects, 144 (46.6% of them exhibited hypertension before surgery, a significantly higher ratio than that of the whole population. One week after surgery, blood pressure of 106 (73.6% patients turned back to normal. Blood pressure of another 37(25.7% patients decreased with different degrees, although still higher than normal. Moreover, it appears that both approaches were effective in improving blood pressure, while the posterior approach was more effective in decreasing systolic blood pressure. We speculate this type of hypertension might result from hyperactivity of sympathetic nervous system as the heart rate of these patients decreased after surgery as well. Collectively, compression of spinal cord in CSM patients might be associated with hypertension, and decompression surgery largely attenuated this type of hypertension. These findings prove CSM to be a potential associated factor of high blood pressure and may shed light on therapies of hypertension in clinics.

Analysis of insecticide resistance-related genes of the Carmine spider mite Tetranychus cinnabarinus based on a de novo assembled transcriptome.

Directory of Open Access Journals (Sweden)

Zhifeng Xu

Full Text Available The carmine spider mite (CSM, Tetranychus cinnabarinus, is an important pest mite in agriculture, because it can develop insecticide resistance easily. To gain valuable gene information and molecular basis for the future insecticide resistance study of CSM, the first transcriptome analysis of CSM was conducted. A total of 45,016 contigs and 25,519 unigenes were generated from the de novo transcriptome assembly, and 15,167 unigenes were annotated via BLAST querying against current databases, including nr, SwissProt, the Clusters of Orthologous Groups (COGs, Kyoto Encyclopedia of Genes and Genomes (KEGG and Gene Ontology (GO. Aligning the transcript to Tetranychus urticae genome, the 19255 (75.45% of the transcripts had significant (e-value <10-5 matches to T. urticae DNA genome, 19111 sequences matched to T. urticae proteome with an average protein length coverage of 42.55%. Core Eukaryotic Genes Mapping Approach (CEGMA analysis identified 435 core eukaryotic genes (CEGs in the CSM dataset corresponding to 95% coverage. Ten gene categories that relate to insecticide resistance in arthropod were generated from CSM transcriptome, including 53 P450-, 22 GSTs-, 23 CarEs-, 1 AChE-, 7 GluCls-, 9 nAChRs-, 8 GABA receptor-, 1 sodium channel-, 6 ATPase- and 12 Cyt b genes. We developed significant molecular resources for T. cinnabarinus putatively involved in insecticide resistance. The transcriptome assembly analysis will significantly facilitate our study on the mechanism of adapting environmental stress (including insecticide in CSM at the molecular level, and will be very important for developing new control strategies against this pest mite.

Optimization of the composition of the powdered cereal sprouts mixtures

Directory of Open Access Journals (Sweden)

Tumbas-Šaponjac Vesna T.

2016-01-01

Full Text Available Sprouts of cereals have received significant attention as functional food due to their nutritional and functional value. Consumption of sprouts has become increasingly popular among people interested in improving and maintaining their health status by changing dietary habits. Cereal grains contain several classes of phytochemicals, i.e. phenolics, chlorophylls, and carotenoids. However, their nutritional and chemical profile is altered and improved during germination. The purpose of this study was to find the best ratio of the powdered wheat (WS, oat (OS and barley (BS sprouts for designing the cereal sprout mixture (CSM with the highest total phenolic content (TPh and antioxidant capacity (AC, using Simplex-Centroid experimental design and response surface methodology (RSM. Single- and multi-response optimizations showed that OS did not contribute to TPh or AC values of CSM and, therefore, was not included in any of the compositions of the optimized CSM. Single-response optimizations showed that the highest TPh was found for CSM containing 82% BS and 18% WS, while the best AC was found for pure BS. The predicted ratio of cereal sprout powders in CSM obtained by multi-response optimization was: 96% BS and 4% WS. This mixture possessed the highest predicted TPh and AC (372.32 mg GAE/100 g, 549.99 μmol TE/100 g, respectively, which was confirmed to be in accordance with the experimental values. Based on the results obtained in this study, a designed CSM is proposed as a convenient ingredient of functional food products, dietary supplements and nutraceuticals.

Au-delà du vecteur | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

30 mai 2011 ... L'équipe du programme Écosystèmes et santé humaine (ÉCOSANTÉ) du CRDI travaille avec des chercheurs de pays en développement en vue de trouver des solutions aux problèmes de santé humaine reliés à l'état des écosystèmes. Regarder la vidéo sur YouTube (sélectionner le sous-titrage en ...

Aircraft Trajectories Computation-Prediction-Control. Volume 1 (La Trajectoire de l’Avion Calcul-Prediction-Controle)

Science.gov (United States)

1990-03-01

Vigilance and Performance in Automatized Systems. Org.: Prof A. Coblentz Laboratoire d’Anthropologie et d’Ecologie Humaine - Universit& Rene Descartes , PARIS...Humaine - Universit6 Ren6 Descartes , PARIS, September 1988 BOY G., CEP-Onera "Assistance A l’Opdrateur: Une Approche de l’Intelligence Artificielle...Appliqi6e, Universit6 Ren6 Descartes - Paris V "Effect of Monotony on Vigilance and Biomechanical Behaviour" In: Commission of European Communities

Une approche écosanté pour le contrôle de la fièvre de la vallée du ...

International Development Research Centre (IDRC) Digital Library (Canada)

17 août 2016 ... La fièvre de la vallée du Rift est une maladie grave qui se transmet par la piqûre d'un moustique qui infecte l'être humain, le bétail et les animaux sauvages. De plus, les êtres humains peuvent contracter la maladie par tout contact avec des animaux infectés. La maladie s'est répandue dans toute l'Afrique ...

Identification of sulfur-cycle prokaryotes in a low-sulfate lake (Lake Pavin) using aprA and 16S rRNA gene markers.

Science.gov (United States)

Biderre-Petit, Corinne; Boucher, Delphine; Kuever, Jan; Alberic, Patrick; Jézéquel, Didier; Chebance, Brigitte; Borrel, Guillaume; Fonty, Gérard; Peyret, Pierre

2011-02-01

Geochemical researches at Lake Pavin, a low-sulfate-containing freshwater lake, suggest that the dominant biogeochemical processes are iron and sulfate reduction, and methanogenesis. Although the sulfur cycle is one of the main active element cycles in this lake, little is known about the sulfate-reducer and sulfur-oxidizing bacteria. The aim of this study was to assess the vertical distribution of these microbes and their diversities and to test the hypothesis suggesting that only few SRP populations are involved in dissimilatory sulfate reduction and that Epsilonproteobacteria are the likely key players in the oxidative phase of sulfur cycle by using a PCR aprA gene-based approach in comparison with a 16S rRNA gene-based analysis. The results support this hypothesis. Finally, this preliminary work points strongly the likelihood of novel metabolic processes upon the availability of sulfate and other electron acceptors.