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Sample records for hulsberg sarah monson

  1. Tutorial to SARAH

    CERN Document Server

    Staub, Florian

    2016-01-01

    I give in this brief tutorial a short practical introduction to the Mathematica package SARAH. First, it is shown how an existing model file can be changed to implement a new model in SARAH. In the second part, masses, vertices and renormalisation group equations are calculated with SARAH. Finally, the main commands to generate model files and output for other tools are summarised.

  2. HANFORD SAFETY ANALYSIS & RISK ASSESSMENT HANDBOOK (SARAH)

    Energy Technology Data Exchange (ETDEWEB)

    EVANS, C B

    2004-12-21

    The purpose of the Hanford Safety Analysis and Risk Assessment Handbook (SARAH) is to support the development of safety basis documentation for Hazard Category 2 and 3 (HC-2 and 3) U.S. Department of Energy (DOE) nuclear facilities to meet the requirements of 10 CFR 830, ''Nuclear Safety Management''. Subpart B, ''Safety Basis Requirements.'' Consistent with DOE-STD-3009-94, Change Notice 2, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Documented Safety Analyses'' (STD-3009), and DOE-STD-3011-2002, ''Guidance for Preparation of Basis for Interim Operation (BIO) Documents'' (STD-3011), the Hanford SARAH describes methodology for performing a safety analysis leading to development of a Documented Safety Analysis (DSA) and derivation of Technical Safety Requirements (TSR), and provides the information necessary to ensure a consistently rigorous approach that meets DOE expectations. The DSA and TSR documents, together with the DOE-issued Safety Evaluation Report (SER), are the basic components of facility safety basis documentation. For HC-2 or 3 nuclear facilities in long-term surveillance and maintenance (S&M), for decommissioning activities, where source term has been eliminated to the point that only low-level, residual fixed contamination is present, or for environmental remediation activities outside of a facility structure, DOE-STD-1120-98, ''Integration of Environment, Safety, and Health into Facility Disposition Activities'' (STD-1120), may serve as the basis for the DSA. HC-2 and 3 environmental remediation sites also are subject to the hazard analysis methodologies of this standard.

  3. Erfolgreiche Ambivalenz. Sarah Bernhardts Inszenierungen von Weiblichkeit Successful Ambivalence: Sarah Bernhardt’s Staging of Femininity

    Directory of Open Access Journals (Sweden)

    Doris Kolesch

    2007-03-01

    Full Text Available Claudia Thorun untersucht die Inszenierungen von Weiblichkeit am Beispiel der Schauspielerin Sarah Bernhardt, die im späten 19. und beginnenden 20. Jahrhundert zu den erfolgreichsten Künstlerinnen ihrer Zeit gehörte. Dazu werden die Darstellungen ausgewählter Rollenfiguren ebenso analysiert wie die schauspieltheoretischen Überlegungen Bernhardts und schließlich die Rezeption ihres Schaffens in Theaterkritiken, aber auch Werbebildern und Medieninszenierungen. Das lesenswerte Buch erlaubt Einblicke in konkrete theatrale Verkörperungen von Weiblichkeit im Fin de Siècle, unternimmt jedoch keine ausreichende theatergeschichtliche wie kulturwissenschaftliche Kontextualisierung, obwohl die Verfasserin in der Einleitung ihrer Studie das Ziel formuliert, Gendertheorie, Theatergeschichte und Kulturwissenschaft zu verknüpfen.Claudia Thorun examines the staging of femininity using the example of the actress Sarah Bernhardt, who in the late nineteenth century was among the most successful artists of her time. The study includes analyses of the representation of specific roles, Bernhardt’s theories on acting, and finally the reception of her work in theater critiques, as well as advertisement images and representations in the media. The book, which is a worthwhile read, allows for insight into the concrete theatrical embodiment of femininity at the fin de siècle. It does not provide, however, adequate contextualization within theater history nor cultural studies, even though in her introduction, the author asserts that it is her intention to link together gender theory, theater history, and cultural studies.

  4. Exploring new models in all detail with SARAH

    CERN Document Server

    Staub, Florian

    2015-01-01

    I give an overview about the features the Mathematica package SARAH provides to study new models. In general, SARAH can handle a wide range of models beyond the MSSM coming with additional chiral superfields, extra gauge groups, or distinctive features like Dirac gaugino masses. All of these models can be implemented in a compact form in SARAH and are easy to use: SARAH extracts all analytical properties of the given model like two-loop renormalization group equations, tadpole equations, mass matrices and vertices. Also one- and two-loop corrections to tadpoles and self-energies can be obtained. For numerical calculations SARAH can be interfaced to other tools to get the mass spectrum, to check flavour or dark matter constraints, and to test the vacuum stability, or to perform collider studies. In particular, the interface to SPheno allows a precise prediction of the Higgs mass in a given model comparable to MSSM precision by incorporating the important two-loop corrections. I show in great detail at the exam...

  5. SARAH 3.2: Dirac gauginos, UFO output, and more

    Science.gov (United States)

    Staub, Florian

    2013-07-01

    SARAH is a Mathematica package optimized for the fast, efficient and precise study of supersymmetric models beyond the MSSM: a new model can be defined in a short form and all vertices are derived. This allows SARAH to create model files for FeynArts/FormCalc, CalcHep/CompHep and WHIZARD/O'Mega. The newest version of SARAH now provides the possibility to create model files in the UFO format which is supported by MadGraph 5, MadAnalysis 5, GoSam, and soon by Herwig++. Furthermore, SARAH also calculates the mass matrices, RGEs and 1-loop corrections to the mass spectrum. This information is used to write source code for SPheno in order to create a precision spectrum generator for the given model. This spectrum-generator-generator functionality as well as the output of WHIZARD and CalcHep model files has seen further improvement in this version. Also models including Dirac gauginos are supported with the new version of SARAH, and additional checks for the consistency of the implementation of new models have been created. Program summaryProgram title:SARAH Catalogue identifier: AEIB_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIB_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 3 22 411 No. of bytes in distributed program, including test data, etc.: 3 629 206 Distribution format: tar.gz Programming language: Mathematica. Computer: All for which Mathematica is available. Operating system: All for which Mathematica is available. Classification: 11.1, 11.6. Catalogue identifier of previous version: AEIB_v1_0 Journal reference of previous version: Comput. Phys. Comm. 182 (2011) 808 Does the new version supersede the previous version?: Yes, the new version includes all known features of the previous version but also provides the new features mentioned below

  6. Sarah J. Hale High School-Project SABER.

    Science.gov (United States)

    Rosenblatt, Harold

    Project SABER, which operated in Sarah J. Hale High School in South Brooklyn, New York, consisted of bilingual instructional and supportive services to 9th and 10th grade Spanish language students. Students received bilingual instruction in social studies, science, math, and Spanish. All the SABER students received English as a second language…

  7. Linnakirjutaja Sarah J. Portner: Tallinn ei jää Pariisile alla / Sarah J. Portner ; intervjueerinud Mari Peegel

    Index Scriptorium Estoniae

    Portner, Sarah Jana, 1983-

    2011-01-01

    Saksa Ida-Euroopa kultuurifoorumi (Deutsches Kulturforum östliches Europa, Potsdam), Tallinna linna ja kirjanike liidu stipendiumiga viibib 5 kuud Tallinnas ja kirjutab linnakrooniku blogi (tallinna-linnakirjutaja-2011.blogspot.com) Passau ülikoolis kultuuriteooriat õppinud Sarah J. Portner. Blogi fookuses on Euroopa rahvaste ühine ajalugu

  8. Researcher Profile: An Interview with Sarah Asebedo, Ph.D.

    OpenAIRE

    Martie Gillen

    2016-01-01

    Sarah Asebedo, Ph.D., CFP®, is an Assistant Professor of Personal Financial Planning with Texas Tech University. With extensive financial planning practitioner experience, her goal is to connect research and financial planning practice with a focus on the relationship between psychological attributes, financial conflicts, and financial behavior. Her work has been published in the Journal of Financial Planning, Journal of Financial Therapy, Journal of Financial Counselin...

  9. Tuulegeneraatori sündroom: infraheli mahavaikitud mõju / Sarah Laurie ; intervjueerinud Helen Arusoo

    Index Scriptorium Estoniae

    Laurie, Sarah

    2013-01-01

    Austraalia arst ja tuulegeneraatori sündroomi ohvreid abistava rahvusvahelise organisatsiooni Waubra Foundation tegevtirektor Sarah Laurie loodab saada tuulegeneraatori sündroomile meedikute tunnustuse

  10. Researcher Profile: An Interview with Sarah Asebedo, Ph.D.

    Directory of Open Access Journals (Sweden)

    Martie Gillen

    2016-12-01

    Full Text Available Sarah Asebedo, Ph.D., CFP®, is an Assistant Professor of Personal Financial Planning with Texas Tech University. With extensive financial planning practitioner experience, her goal is to connect research and financial planning practice with a focus on the relationship between psychological attributes, financial conflicts, and financial behavior. Her work has been published in the Journal of Financial Planning, Journal of Financial Therapy, Journal of Financial Counseling and Planning, and Financial Planning Review. Asebedo currently serves as President-Elect for the Financial Therapy Association. She earned her Ph.D. in Personal Financial Planning from Kansas State University.

  11. HANFORD SAFETY ANALYSIS and RISK ASSESSMENT HANDBOOK (SARAH)

    International Nuclear Information System (INIS)

    EVANS, C.B.

    2004-01-01

    The purpose of the Hanford Safety Analysis and Risk Assessment Handbook (SARAH) is to support the development of safety basis documentation for Hazard Category 2 and 3 (HC-2 and 3) U.S. Department of Energy (DOE) nuclear facilities to meet the requirements of 10 CFR 830, ''Nuclear Safety Management''. Subpart B, ''Safety Basis Requirements.'' Consistent with DOE-STD-3009-94, Change Notice 2, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Documented Safety Analyses'' (STD-3009), and DOE-STD-3011-2002, ''Guidance for Preparation of Basis for Interim Operation (BIO) Documents'' (STD-3011), the Hanford SARAH describes methodology for performing a safety analysis leading to development of a Documented Safety Analysis (DSA) and derivation of Technical Safety Requirements (TSR), and provides the information necessary to ensure a consistently rigorous approach that meets DOE expectations. The DSA and TSR documents, together with the DOE-issued Safety Evaluation Report (SER), are the basic components of facility safety basis documentation. For HC-2 or 3 nuclear facilities in long-term surveillance and maintenance (S and M), for decommissioning activities, where source term has been eliminated to the point that only low-level, residual fixed contamination is present, or for environmental remediation activities outside of a facility structure, DOE-STD-1120-98, ''Integration of Environment, Safety, and Health into Facility Disposition Activities'' (STD-1120), may serve as the basis for the DSA. HC-2 and 3 environmental remediation sites also are subject to the hazard analysis methodologies of this standard

  12. Mourir/survivre. Lumières de Sarah Kane

    Directory of Open Access Journals (Sweden)

    Martine Delvaux

    2012-01-01

    Full Text Available L’article propose une lecture de la première et de la dernière œuvres de la dramaturge britannique Sarah Kane, Blasted et 4.48 Psychosis, afin de réfléchir sur son legs théâtral. En s’appuyant sur Survivance des lucioles de Georges Didi-Huberman (2009, le texte met en lumière le rapport à l’espoir qui émane de l’œuvre de Kane et de son pessimisme apparent. Delvaux voit, dans l’écriture fragmentée, sarcastique et provocante, non pas le testament d’une artiste cliniquement dépressive mais plutôt un ultime outil de résistance à la noirceur, un refus radical de cette posture cynique que lui attribuait la critique. This article offers a reading of British dramaturge Sarah Kane’s first and last pieces, Blasted and 4.48 Psychosis, in order to reflect on her dramatic heritage. Drawing upon Georges Didi-Huberman’s Survivance des lucioles (2009, the text sheds light on the question of hope in what has been seen as pessimism in Kane’s work. Rather than understanding Kane’s fragmented, sarcastic and provocative writing as a testament of a clinically depressed author, Delvaux sees it as a work of resistance, a desire to see the light in an all-encompassing cultural darkness, suggesting that Kane, in fact, refuses the cynical posturethat critics have associated with her work.

  13. Expression, purification, crystallization and preliminary X-ray analysis of the human NORE1 SARAH domain

    International Nuclear Information System (INIS)

    Kim, Hye Jin; Hwang, Eunha; Han, Young-Hyun; Choi, Saehae; Lee, Woo Cheol; Kim, Hye-Yeon; Jeon, Young Ho; Cheong, Chaejoon; Cheong, Hae-Kap

    2012-01-01

    The crystallization of the human NORE1 SARAH domain is reported. NORE1 is an important tumour suppressor in human cancers that interacts with the pro-apoptotic protein kinase MST1/2 through SARAH domains. The SARAH domain (residues 366–413) of human NORE1 was expressed in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion method. The crystal diffracted to 2.7 Å resolution and belonged to space group P6 1 22, with unit-cell parameters a = b = 73.041, c = 66.092 Å, α = β = 90, γ = 120°

  14. Nüüdiskunst on maailmas hinnas / Sarah Cosulich Canarutto ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Cosulich Canarutto, Sarah

    2004-01-01

    Põhja-Itaalias Passariano villa Maninis avatud kaasaegse kunsti keskuse kuraator Sarah Cosulich Canarutto uue kunstikeskuse tulevikuplaanidest. Keskust juhatab Francesco Bonami. Alustati näitustega "Love/Hate" ja "Vernice"

  15. Two-loop Higgs mass calculations beyond the MSSM with SARAH and SPheno

    Energy Technology Data Exchange (ETDEWEB)

    Nickel, Kilian [Physikalisches Institut, Universitaet Bonn (Germany); Staub, Florian [Theory Division, CERN, Geneva (Switzerland); Goodsell, Mark [LPTHE, UPMC Univ. Paris 06 (France)

    2015-07-01

    We present a recent extension to the Mathematica package SARAH which allows for Higgs mass calculations at the two-loop level in a wide range of supersymmetric models beyond the MSSM. These calculations are based on the effective potential approach. For the numerical evaluation Fortran code for SPheno is generated by SARAH. This allows to predict the Higgs mass in more complicated SUSY theories with a similar precision as most state-of-the-art spectrum generators do for the MSSM.

  16. SARAH 4: A tool for (not only SUSY) model builders

    Science.gov (United States)

    Staub, Florian

    2014-06-01

    We present the new version of the Mathematica package SARAH which provides the same features for a non-supersymmetric model as previous versions for supersymmetric models. This includes an easy and straightforward definition of the model, the calculation of all vertices, mass matrices, tadpole equations, and self-energies. Also the two-loop renormalization group equations for a general gauge theory are now included and have been validated with the independent Python code PyR@TE. Model files for FeynArts, CalcHep/CompHep, WHIZARD and in the UFO format can be written, and source code for SPheno for the calculation of the mass spectrum, a set of precision observables, and the decay widths and branching ratios of all states can be generated. Furthermore, the new version includes routines to output model files for Vevacious for both, supersymmetric and non-supersymmetric, models. Global symmetries are also supported with this version and by linking Susyno the handling of Lie groups has been improved and extended.

  17. Sarah Louise Heath Palin. Siivutu raamatukogutädi tõus päästeingliks / Hendrik Vosman

    Index Scriptorium Estoniae

    Vosman, Hendrik

    2008-01-01

    Ilmunud ka: Postimees : na russkom jazõke 12. sept. lk. 8. Vabariiklaste asepresidendikandidaati Sarah Palini koolitab välispoliitika valdkonnas välja president George W. Bushi endistest nõunikest koosnev meeskond. Sarah Palini poliitilisest karjäärist Alaskas ning valimisest asepresidendikandidaadiks. Lisa: 5 fakti

  18. Laura Mariani, Sarah Bernhardt, Colette e l'arte del travestimento ...

    African Journals Online (AJOL)

    User

    Laura Mariani, Sarah Bernhardt, Colette e l'arte del travestimento,. Bologna, Il Mulino, 1996. Anche questo secondo libro che Laura Mariani dedica alla storia delle attrici si svolge al confine tra storia del teatro e storia delle donne: un intreccio fertile di suggestioni e spunti teorici. Tema dell'indagine, condotta soprattutto ...

  19. A Revolution in the Education of Women. Ten Years of Continuing Education at Sarah Lawrence College.

    Science.gov (United States)

    Richter, Melissa Lewis; Whipple, Jane Banks

    The Sarah Lawrence Continuing Education Center provides educational opportunities for women who are not now in college, but who wish to continue their educations. This book is a publication about and a catalog for the Continuing Education Center. The Undergraduate Program is explained, as are procedures for admission, financial aid, course work,…

  20. Tea with Mother: Sarah Palin and the Discourse of Motherhood as a Political Ideal

    Directory of Open Access Journals (Sweden)

    Janet McCabe

    2016-02-01

    Full Text Available Seldom has someone emerged so unexpectedly and sensationally on to the American political scene as Sarah Palin. With Palin came what had rarely, if ever, been seen before on a presidential trail: hockey moms, Caribou-hunting, pitbulls in lipstick parcelled as political weaponry. And let’s not forget those five children, including Track 19, set to deploy to Iraq, Bristol, and her unplanned pregnancy at 17, and Trig, a six-month-old infant with Down’s syndrome. Never before had motherhood been so finely balanced with US presidential politics. Biological vigour translated into political energy, motherhood transformed into an intoxicating political ideal. This article focuses on Sarah Palin and how her brand of “rugged Alaskan motherhood” (PunditMom 2008 became central to her media image, as well as what this representation has to tell us about the relationship between mothering as a political ideal, US politics, and the media.

  1. The Sarah evaluation scale for children and adolescents with cerebral palsy: description and results

    Directory of Open Access Journals (Sweden)

    Katia S. Pinto

    2016-01-01

    Full Text Available ABSTRACT Background Assessments of motor-functional aspects in cerebral palsy are crucial to rehabilitation programs. Objective To introduce the Sarah motor-functional evaluation scale and to report the initial results of its measurement properties. This scale was created based on the experience of the Sarah Network of Rehabilitation Hospitals in the care of children and adolescents with cerebral palsy. Method Preliminary results concerning the measurement properties of the scale were obtained via assessment of 76 children and adolescents with cerebral palsy. Experts' opinions were used to determine an expected empirical score by age group and to differentiate severity levels. Results The scale exhibited a high Cronbach’s alpha coefficient (0.95. Strong correlation was observed with experts’ classification for severity levels (0.81 to 0.97 and with the scales Gross Motor Function Measure and Pediatric Evaluation of Disability Inventory (0.80 to 0.98. Regression analysis detected a significant relationship between the scale score and the severity of the child’s motor impairment. The inter-rater reliability was also strong (intraclass correlation coefficient ranging from 0.98 to 0.99. The internal responsiveness of the scale score was confirmed by significant differences between longitudinal evaluations (paired Student’s t test with p<0.01; standardized response mean of 0.60. Conclusion The Sarah scale provides a valid measure for assessing the motor skills and functional performance of children and adolescents with cerebral palsy. The preliminary results showed that the Sarah scale has potential for use in routine clinical practice and rehabilitation units.

  2. “Feminism” as Ideology: Sarah Palin’s Anti-feminist Feminism and Ideology Critique

    Directory of Open Access Journals (Sweden)

    Michelle Rodino-Colocino

    2012-05-01

    Full Text Available The point of this essay is threefold: to describe the main tenets of Marx’s theory of ideology by critically engaging in the work of Marx and Engels, to flesh out the claim that Sarah Palin’s  “feminism” works ideologically as Marx and Engels describe, and consequently, to demonstrate that ideology critique is important intellectual work for feminist Marxist scholars. As I suggest in the conclusion, this is work that should inform scholars’ political activism.

  3. Be Afraid: Sarah Palin and the Emergence of a Neoconservative Feminist Standpoint

    OpenAIRE

    Farrell Kelly, John

    2009-01-01

    In August 2008, U.S. Republican presidential candidate John McCain chose Alaska Governor Sarah Palin to be the vice presidential candidate. Palin’s selection evoked a range of passionate responses. Many people were shocked: some were shocked and elated, some were shocked and appalled, and some were shocked and emotionally torn. In addition to evoking passionate responses, Palin’s selection foregrounded a wide range of issues relating to gender: the historical gender disparity in candidates, t...

  4. Stan Hawkins et Sarah Niblock, Prince: The Making of a Pop Music Phenomenon

    OpenAIRE

    Guedj, Pauline

    2014-01-01

    Prince: The Making of a Pop Music Phenomenom constitue l’une des premières publications académiques consacrée à Prince. Ses auteurs, Stan Hawkins, musicologue et Sarah Niblock, professeur en journalisme, s’y donnent pour but de remettre le « phénomène » Prince au cœur des débats sur les cultures populaires nord-américaines et de revenir sur la figure particulière de cet artiste dans l'élaboration d'expériences musicales ancrées dans les deux dernières décennies du vingtième siècle et les dix ...

  5. Divided Spirits. Tequila, Mezcal, and The Politics of Production, de Sarah Bowen

    Directory of Open Access Journals (Sweden)

    Olga I. Mancha Caceres

    2017-05-01

    Full Text Available Sarah Bowen, profesora asociada del Departamento de Sociologia y Antropologia de la Universidad Estatal de Carolina del Norte, presenta en Divided Spirits. Tequila, Mezcal, and The Politics of Production, el resultado de algo mas de una década de trabajo sobre las denominaciones de origen (DO en México, Francia y Estados Unidos, en el que nos presenta un profundo analisis del complejo mundo de la producción y comercialización del tequila y el mezcal ¿dos productos identitarios de México?, las dinamicas sociales, económicas y politicas que promueven y el papel de sus multiples y desiguales actores involucrados.

  6. Just emotions: Reading the Sarah and Hagar narrative (Genesis 16, 21 through the lens of human dignity

    Directory of Open Access Journals (Sweden)

    Juliana Claassens

    2013-09-01

    Full Text Available This article seeked to read the interconnected narratives of Sarah and Hagar (Genesis 16, 21 in terms of the hermeneutical lens of human dignity. For the purpose of this article, recent studies on the performative nature of emotions, which considered the central role of emotions such as pain, disgust and hatred in shaping the lives of individuals as well as the ways in which people relate to one another, were helpful in contemplating the situations of dehumanisation faced by both Sarah and Hagar as well as the broader question regarding upholding human worth in a context of indignity. This article furthermore considered the role of emotions in a conversation on ethics and particularly the way in which the narrative offered a fruitful avenue for considering Israel�s relationship to their neighbours � a line of interpretation that holds potential for reflecting on complex interracial and interethnic relationships in today�s global context.

  7. Roy Ellen, Stephen J. Lycett, Sarah E. Johns, eds., 2013, Understanding Cultural Transmission in Anthropology: A Critical Synthesis New York and Oxford: Berghahn Books

    Directory of Open Access Journals (Sweden)

    Clelia Viecelli

    2015-10-01

    Full Text Available recensione: Roy Ellen, Stephen J. Lycett, Sarah E. Johns, eds., 2013, Understanding Cultural Transmission in Anthropology: A Critical Synthesis New York and Oxford: Berghahn Books di Clelia Viecelli

  8. Sarah Schulman’s Empathy, Ties that Bind, and the Possibilities of the Stranger

    Directory of Open Access Journals (Sweden)

    Amy Tziporah Karp

    2017-09-01

    Full Text Available In her novel 'Empathy' (1992, Sarah Schulman imagines what it means to be caught between the assimilation of Ashkenazi Jewish Americans and the otherness of Eastern Europe. Schulman’s protagonist Anna O. traverses many landscapes and, unlike other characters in the novel that work to transcend their stranger identity, Anna O. makes a new life for herself through negotiating what I will call a liminal identity. For Schulman, the task of illuminating the stranger condition that her main character inhabits is a tricky one. While characters of earlier Jewish American texts by writers such as Anzia Yezierska were readily understood as strangers working towards ‘becoming American’, it is implicitly accepted that Anna O., living in queer 1990s New York City, is already a completely assimilated American. Schulman uses a variety of narrative strategies that culminate in a somewhat messy palimpsest attempting to convey the nuanced experience of the stranger. The resulting textual fragmentation removes any stable point of reference so that scholars and readers of 'Empathy' must reconstruct various narrative elements in trying to make sense of Anna O.’s world. One is left to consult volumes of critical work that hardly get to the heart of Anna O.’s Jewish queer experience, to piece them together into a patchwork that may, by its end, accomplish the task of excavating Schulman’s postmodern stranger. In this article I argue that inhabiting the position of the stranger allows Anna O. the possibility of creating some sort of coexistence between, and cohabitation of, her queer and Jewish identities. In this way, Schulman constructs the stranger as a subject position replete with possibility rather than as a liability that must be shed in order to acculturate onself to American life.

  9. The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease.

    Science.gov (United States)

    Lee, Soojin; Bang, Se Min; Hong, Yoon Ki; Lee, Jang Ho; Jeong, Haemin; Park, Seung Hwan; Liu, Quan Feng; Lee, Im-Soon; Cho, Kyoung Sang

    2016-03-01

    Expression of the Down syndrome critical region 1 (DSCR1) protein, an inhibitor of the Ca(2+)-dependent phosphatase calcineurin, is elevated in the brains of individuals with Down syndrome (DS) or Alzheimer's disease (AD). Although increased levels of DSCR1 were often observed to be deleterious to neuronal health, its beneficial effects against AD neuropathology have also been reported, and the roles of DSCR1 on the pathogenesis of AD remain controversial. Here, we investigated the role of sarah (sra; also known as nebula), a Drosophila DSCR1 ortholog, in amyloid-β42 (Aβ42)-induced neurological phenotypes in Drosophila. We detected sra expression in the mushroom bodies of the fly brain, which are a center for learning and memory in flies. Moreover, similar to humans with AD, Aβ42-expressing flies showed increased Sra levels in the brain, demonstrating that the expression pattern of DSCR1 with regard to AD pathogenesis is conserved in Drosophila. Interestingly, overexpression of sra using the UAS-GAL4 system exacerbated the rough-eye phenotype, decreased survival rates and increased neuronal cell death in Aβ42-expressing flies, without modulating Aβ42 expression. Moreover, neuronal overexpression of sra in combination with Aβ42 dramatically reduced both locomotor activity and the adult lifespan of flies, whereas flies with overexpression of sra alone showed normal climbing ability, albeit with a slightly reduced lifespan. Similarly, treatment with chemical inhibitors of calcineurin, such as FK506 and cyclosporin A, or knockdown of calcineurin expression by RNA interference (RNAi), exacerbated the Aβ42-induced rough-eye phenotype. Furthermore, sra-overexpressing flies displayed significantly decreased mitochondrial DNA and ATP levels, as well as increased susceptibility to oxidative stress compared to that of control flies. Taken together, our results demonstrating that sra overexpression augments Aβ42 cytotoxicity in Drosophila suggest that DSCR1

  10. The calcineurin inhibitor Sarah (Nebula exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Soojin Lee

    2016-03-01

    Full Text Available Expression of the Down syndrome critical region 1 (DSCR1 protein, an inhibitor of the Ca2+-dependent phosphatase calcineurin, is elevated in the brains of individuals with Down syndrome (DS or Alzheimer's disease (AD. Although increased levels of DSCR1 were often observed to be deleterious to neuronal health, its beneficial effects against AD neuropathology have also been reported, and the roles of DSCR1 on the pathogenesis of AD remain controversial. Here, we investigated the role of sarah (sra; also known as nebula, a Drosophila DSCR1 ortholog, in amyloid-β42 (Aβ42-induced neurological phenotypes in Drosophila. We detected sra expression in the mushroom bodies of the fly brain, which are a center for learning and memory in flies. Moreover, similar to humans with AD, Aβ42-expressing flies showed increased Sra levels in the brain, demonstrating that the expression pattern of DSCR1 with regard to AD pathogenesis is conserved in Drosophila. Interestingly, overexpression of sra using the UAS-GAL4 system exacerbated the rough-eye phenotype, decreased survival rates and increased neuronal cell death in Aβ42-expressing flies, without modulating Aβ42 expression. Moreover, neuronal overexpression of sra in combination with Aβ42 dramatically reduced both locomotor activity and the adult lifespan of flies, whereas flies with overexpression of sra alone showed normal climbing ability, albeit with a slightly reduced lifespan. Similarly, treatment with chemical inhibitors of calcineurin, such as FK506 and cyclosporin A, or knockdown of calcineurin expression by RNA interference (RNAi, exacerbated the Aβ42-induced rough-eye phenotype. Furthermore, sra-overexpressing flies displayed significantly decreased mitochondrial DNA and ATP levels, as well as increased susceptibility to oxidative stress compared to that of control flies. Taken together, our results demonstrating that sra overexpression augments Aβ42 cytotoxicity in Drosophila suggest that DSCR1

  11. SARAH goes left and right looking beyond the Standard Model and meets SUSY

    Energy Technology Data Exchange (ETDEWEB)

    Opferkuch, Toby Oliver

    2017-07-07

    Progress in the search for physics beyond the Standard Model (BSM) proceeds through two main avenues. The first requires the development of models that address the host of theoretical and experimental deficiencies of the Standard Model (SM). The second avenue requires scrutinising these models against all available data as well as checks for theoretical consistency. Unfortunately there exists a large number of strongly motivated models as well as an absence of any signs illuminating the correct path nature has chosen. With the lack of a clear direction, automated tools provide an effective means to test as many models as possible. In this thesis we demonstrate how the SARAH framework can be used in this context as well as its adaptability for confronting unexpected hints of new physics, such as the diphoton excess, that have arisen at the Large Hadron Collider (LHC) over the previous years. We then turn to more theoretical constraints namely, studying the stability of the electroweak vacuum in minimal supersymmetric models. Here we studied the impact of previously neglected directions when including non-standard vacuum expectation values. In the second half of this thesis we consider low-scale left-right symmetric models both with and without supersymmetry. In the non-supersymmetric case we consider constraints arising from charged lepton flavour violation. We have significantly improved existing parametrisations allowing for the new Yukawa couplings to be determined as a function of the underlying model parameters. The last scenario we consider is a model based on SO(10) unification at the high-scale. We build a complete model with TeV-scale breaking of the left-right phase studying in detail the phenomenology.

  12. Sarah Ysalgué Ysalgué: una figura de la ciencia y la pedagogía en Cuba

    Directory of Open Access Journals (Sweden)

    Jesús Piclín Minot

    2017-11-01

    Full Text Available En el presente artículo se aborda el estudio de la vida y obra de personalidades como objeto de estudio inherente a este campo del saber científico. Las ideas cardinales que en él se desarrollan, se sostienen en torno a la Dra. Sarah Ysalgué como una figura de la ciencia en Cuba, por su contribución a la Geografía como ciencia y su enseñanza.

  13. Outcasts Searching for a Place To Fit: A Study of "Frankenstein" by Mary Shelley and "Staying Fat for Sarah Byrnes" by Chris Crutcher.

    Science.gov (United States)

    Martin, Amy

    All people have to deal with feelings of loneliness, isolation, fear, and lack of acceptance, especially in the teenage years. Both of the novels "Staying Fat for Sarah Byrnes" and "Frankenstein" deal with these issues. By 10th grade, students are really searching for who they are and what they want out of life. It is…

  14. Doing justice to the political: the International Criminal Court in Uganda and Sudan: a reply to Sarah Nouwen and Wouter Werner

    NARCIS (Netherlands)

    Schotel, B.

    2011-01-01

    This article is a reaction to Sarah Nouwen and Wouter Werner, ‘Doing Justice to the Political. The International Criminal Court in Uganda and Sudan’, 21 EJIL (2010) 941. It takes issue with attempts to understand international law and particularly the workings of the International Criminal Court in

  15. Lesson Development for English Learners in Content Area Settings: Key Considerations. Q&A with Sarah Catherine K. Moore, Ph.D. 2016 Educator Effectiveness Webinar Series

    Science.gov (United States)

    Moore, Sarah Catherine K.

    2016-01-01

    In this webinar, Dr. Sarah Catherine K. Moore, Program Director at the Center for Applied Linguistics, outlined factors for content area teachers to consider as they design and deliver lessons for mainstream classrooms that include English learner (EL) students. This Q&A addressed the questions participants had for Dr. Moore following the…

  16. A Web-Based Training Resource for Therapists to Deliver an Evidence-Based Exercise Program for Rheumatoid Arthritis of the Hand (iSARAH): Design, Development, and Usability Testing.

    Science.gov (United States)

    Srikesavan, Cynthia Swarnalatha; Williamson, Esther; Eldridge, Lucy; Heine, Peter; Adams, Jo; Cranston, Tim; Lamb, Sarah E

    2017-12-13

    The Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH) is a tailored, progressive exercise program for people having difficulties with wrist and hand function due to rheumatoid arthritis (RA). The program was evaluated in a large-scale clinical trial and was found to improve hand function, was safe to deliver, and was cost-effective. These findings led to the SARAH program being recommended in the UK National Institute for Health and Care Excellence guidelines for the management of adults with RA. To facilitate the uptake of this evidence-based program by clinicians, we proposed a Web-based training program for SARAH (iSARAH) to educate and train physiotherapists and occupational therapists on delivering the SARAH program in their practice. The overall iSARAH implementation project was guided by the 5 phases of the analysis, design, development, implementation, and evaluation (ADDIE) system design model. The objective of our study was to conduct the first 3 phases of the model in the development of the iSARAH project. Following publication of the trial, the SARAH program materials were made available to therapists to download from the trial website for use in clinical practice. A total of 35 therapists who downloaded these materials completed an online survey to provide feedback on practice trends in prescribing hand exercises for people with RA, perceived barriers and facilitators to using the SARAH program in clinical practice, and their preferences for the content and Web features of iSARAH. The development and design of iSARAH were further guided by a team of multidisciplinary health professionals (n=17) who took part in a half-day development meeting. We developed the preliminary version of iSARAH and tested it among therapists (n=10) to identify and rectify usability issues and to produce the final version. The major recommendations made by therapists and the multidisciplinary team were having a simple Web design and layout, clear

  17. Sarah Sepulchre, dir. Décoder les séries télévisées.

    Directory of Open Access Journals (Sweden)

    Jan Baetens

    2011-08-01

    Full Text Available

    Sarah Sepulchre, dir. Décoder les séries télévisées.

    Bruxelles: De Boeck, coll. InfoCom, 2011-06-22 ISBN 978-2-8041-6375-4

  18. NRDA-processed CTD data from the Sarah Bordelon in the Gulf of Mexico, Cruise 7 Leg 1, collected from 2010-12-04 to 2010-12-19, associated with the Deepwater Horizon Oil Spill event (NCEI Accession 0130702)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conductivity Temperature and Depth (CTD) measurements were collected aboard the M/V Sarah Bordelon, Cruise 07 to determine physical oceanographic parameters of the...

  19. Her Excellency Mrs Sarah Gillett Her Majesty's Ambassador to the Swiss Confederation United Kingdom of Great Britain and Northern Ireland on the occasion of the Antony Gormley sculpture unveiling ceremony Wednesday 7th December 2011

    CERN Document Server

    Maximilien Brice

    2011-01-01

    Her Excellency Mrs Sarah Gillett Her Majesty's Ambassador to the Swiss Confederation United Kingdom of Great Britain and Northern Ireland on the occasion of the Antony Gormley sculpture unveiling ceremony Wednesday 7th December 2011

  20. The gendered embodiment of shame: Intersections of acquaintance rape, trauma and self-blame in Pompidou posse by Sarah Lotz

    Directory of Open Access Journals (Sweden)

    Jessica Murray

    2014-08-01

    Full Text Available This article offers a feminist literary analysis of the gendered embodiment of shame in Pompidou posse by Sarah Lotz. In this novel, Lotz depicts female characters who are sexually assaulted by acquaintances and the resultant shame and trauma reside in their bodies. I will demonstrate that the embodied shame of these characters is distinctly gendered and that this shapes their attempts to cope with the aftermath of the sexual assaults. A close reading of the text reveals that the characters are exposed to overwhelming social messages of female culpability in a larger context that is rife with misogyny. As a result, they anticipate blame to such an extent that they blame themselves and internalise this blame as shame. By focusing on the bodies of the survivors, Lotz demonstrates the embodiment of shame, but she also suggests a corporeal challenge to silencing. The bodies of these characters speak loudly, albeit sometimes in the halting language of trauma, and they function to alert them to danger, to help them excavate memories that are made inaccessible and to testify to traumatic sexual assault.

  1. Là que la mort vit. Sur les théâtres de Jon Fosse, Sarah Kane et Rodrigo García

    OpenAIRE

    Rafis, V.

    2012-01-01

    Should theatre come about through the meeting of printed matter on paper and of a place in which to execute it, then death – offering neither the ability to say nor to do – can only ever appear foreign to it. Deprived of words and of images, and shrouded in both dissolution and silence, this death is seconded only by nothingness – the nothingness itself according no representation. In spite of this, representing death is the work undertaken by Jon Fosse, Sarah Kane and Rodrigo García. With re...

  2. Tallinna vanalinn on punaseim paik, mida rännates olen näinud! / Sarah Jana Portner ; intervjueerinud Maarja-Liis Arujärv, Oliver Õunmaa

    Index Scriptorium Estoniae

    Portner, Sarah Jana, 1983-

    2011-01-01

    Intervjuu sakslannast ajakirjaniku Sarah Jana Portneriga, kelle Saksa Ida-Euroopa Kultuurifoorum valis Tallinna linnakirjutajaks. Kirjutatu läheb kirja Tallinna-teemalisse blogisse. 26. septembril avab Portner Tallinna Ülikooli Akadeemilise Raamatukogu fuajees fotonäituse "Tallinn - inimeste ja majade lood". Näitus annab ettekujutuse, mis toimub Tallinna vanalinna fassaadide taga ning kes seal elavad

  3. Wirklich wie im wirklichen Leben. Sarah Kember untersucht die (Re-Produktion des kleinen Unterschieds und seiner großen Folgen in Theorie und Praxis von Artificial Life Real as in real life. Sarah Kember examines the (reproduction of ‘the small difference and its big consequences’ in the theory and practice of artificial life.

    Directory of Open Access Journals (Sweden)

    Verena Kuni

    2004-03-01

    Full Text Available Wie greifen diese ‚virtuellen Realitäten‘ in unsere Körper- und Identitätskonzepte, unsere Subjekt- und Geschlechtervorstellungen ein? Sarah Kembers Buch verspricht, erhellende Schneisen durch das Dickicht der definitionsmächtigen Diskurse, Konzepte und Konstruktionen zu schlagen und neue Wege für feministische Interventionen in die Auseinandersetzungen um ‚Artificial Life‘ aufzuzeigen.ow a way through the labyrinth of discourse, concepts and constructions, and to open the door for feminist interpretations in debates about artificial life.

  4. AN ANALYSIS OF THE HADICAL STORY OF PROPHET IBRAHIM AND SARAH WITH A ZHOLIM KING AS A TEACHING MATERIAL IN ISLAMIC EDUCATION

    Directory of Open Access Journals (Sweden)

    Salmah Salmah

    2018-04-01

    Full Text Available In the world of education, a delivery of stories is one of the effective strategies to deliver educational materials to children or learners. As the matter of facts, sometimes the stories told to the children or learners are taken from untruthful sources or fairy tales that will cause a delusion in the child's mind. It is important for parents or educators to convey valued stories coming from the teachings of Islamic values, such as the stories of the previous people delivered by the Prophet Mohammad through his traditions. The purpose of this study is to examine the editorial accounts of the story of the prophet Abraham and Sarah with the zholim King, and to know the understanding of the hadith and the educational analysis associated with this hadith. To obtain the information on the hadith about the story, the researcher uses a takhrîj hadith method, in as much as, it was found there are various relevant hadiths of the Prophet Muhammad related to the story. These hadiths have been analyzed for their historical qualities and linked them with Islamic education materials.

  5. “Knaller-Sex für alle”: Popfeminist Body Politics in Lady Bitch Ray, Charlotte Roche, and Sarah Kuttner

    Directory of Open Access Journals (Sweden)

    Carrie Smith-Prei

    2011-01-01

    Full Text Available Germany has seen a recent upsurge in publications proclaiming that feminism is again an urgent matter for a new generation of women. Faced with the reactionary demography debate and the hegemony of second-wave feminism, young writers, musicians, journalists, and critics call for new models of feminism relevant to women today. As one of these viable models, popfeminism draws on dominant trends in mass culture, on pop’s forty-year history as a cultural prefix in Germany, and on traditional feminism in order to create a new, ostensibly apolitical, feminist subculture based in self-stylization and individual autonomy. Shared by many popfeminist sources is the depiction of negatively coded female corporeality. This article begins with a theoretical analysis of writings on sexuality and the body in recent (popfeminist nonfiction. It then examines the negative corporeal self-stylizations in Turkish-German rapper Lady Bitch Ray’s performances since 2006, in former music video host Charlotte Roche’s novel Feuchtgebiete (2008, and in media personality Sarah Kuttner’s novel Mängelexemplar (2009. Ultimately, these negatively coded bodies are shown to uncover popfeminism’s political intent.

  6. “A horror so deep only ritual can contain it”: The art of dying in the theatre of Sarah Kane

    Directory of Open Access Journals (Sweden)

    Sara Soncini

    2010-10-01

    Full Text Available Death is an overarching presence in Sarah Kane's dramatic universe, peopled by characters charging towards death, and usually encountering it in scenes of Grand Guignol excess and grotesque violence. Death is ambivalently presented as the only escape from the nightmare of living and, at the same time, as that which makes living a nightmare; as the moment of "complete sanity and humanity" in which "everything suddenly connects", and as the ultimate, irrevocable and unredeemable act of self-annihilation. Following Kane's turn towards a more poetic form of drama, in her last two plays this discourse of death is handed over to the words nameless characters or unidentified voices who are likewise engaged in a long, painful quest for selfhood pivoting on the awareness of mortality and the simultaneous dread of and longing for death it engenders. This essay focuses on the ritual quality of the death scenes and/or narratives that crowd Kane's drama. Throughout her work, dying is never an easy, straightforward business, but rather a long, complicated, and at times frustrating mise en scène which also entails rehearsing a repertory of traditional rituals and, once their shortcomings become apparent, devising and testing new ones. The amount of theatricality involved in the art of dying is foregrounded through a web of intertextual references to other literary and/or dramatic sources; this dialogue ties in with a self-reflexive probing of the theatre's ability to provide a ritual that will be capable of "contain[ing] the horror" by supplying a formal framework to express, embody and experience death collectively.

  7. Strengthening and stretching for rheumatoid arthritis of the hand (SARAH: design of a randomised controlled trial of a hand and upper limb exercise intervention - ISRCTN89936343

    Directory of Open Access Journals (Sweden)

    Adams Jo

    2012-11-01

    Full Text Available Abstract Background Rheumatoid Arthritis (RA commonly affects the hands and wrists with inflammation, deformity, pain, weakness and restricted mobility leading to reduced function. The effectiveness of exercise for RA hands is uncertain, although evidence from small scale studies is promising. The Strengthening And Stretching for Rheumatoid Arthritis of the Hand (SARAH trial is a pragmatic, multi-centre randomised controlled trial evaluating the clinical and cost effectiveness of adding an optimised exercise programme for hands and upper limbs to best practice usual care for patients with RA. Methods/design 480 participants with problematic RA hands will be recruited through 17 NHS trusts. Treatments will be provided by physiotherapists and occupational therapists. Participants will be individually randomised to receive either best practice usual care (joint protection advice, general exercise advice, functional splinting and assistive devices or best practice usual care supplemented with an individualised exercise programme of strengthening and stretching exercises. The study assessors will be blinded to treatment allocation and will follow participants up at four and 12 months. The primary outcome measure is the Hand function subscale of the Michigan Hand Outcome Questionnaire, and secondary outcomes include hand and wrist impairment measures, quality of life, and resource use. Economic and qualitative studies will also be carried out in parallel. Discussion This paper describes the design and development of a trial protocol of a complex intervention study based in therapy out-patient departments. The findings will provide evidence to support or refute the use of an optimised exercise programme for RA of the hand in addition to best practice usual care. Trial registration Current Controlled Trials ISRCTN89936343

  8. ‘The resonance of ruins and the question of history’: Southeast Asia in Ruins: Art and Empire in the Early 19th Century, by Sarah Tiffin, Singapore: NUS Press, 2016,

    Directory of Open Access Journals (Sweden)

    Anna Blair

    2017-12-01

    Full Text Available Southeast Asia in Ruins: Art and Empire in the Early 19th Century, by Sarah Tiffin, offers an overview of eighteenth-century interpretations of ruin as applied to the images of Java’s abandoned temples that illustrated Thomas Stamford Raffles’ The History of Java. These images were surrounded by discourse on aesthetics, politics, and religion that served to reinforce British beliefs in their own cultural superiority, and Tiffin argues that this was particularly the case in Raffles’ book, which served as a retrospective justification of his administration and reflected his personal feelings of loss. In this review, I argue that Southeast Asia in Ruins raises interesting questions about the nature of historical objectivity, visual literacy and cross-cultural ruin appreciation that have relevance beyond the period examined by the book.

  9. 2541-IJBCS-Article-Nwozo Sarah Onyenib

    African Journals Online (AJOL)

    hp

    Due to high cost of protein relative to other major nutrients, as part of search for cheaper alternative source for good quality protein for dietary purposes, we evaluated Detarium senegalense seed meal by comparing growth ..... oxidative stress are shown on Tables 5 and 6 ..... metabolism and biochemical regulation in the.

  10. VizieR Online Data Catalog: Standard Galactic field RR Lyrae. I. Photometry (Monson+, 2017)

    Science.gov (United States)

    Monson, A. J.; Beaton, R. L.; Scowcroft, V.; Freedman, W. L.; Madore, B. F.; Rich, J. A.; Seibert, M.; Kollmeier, J. A.; Clementini, G.

    2017-06-01

    The Three-hundred MilliMeter Telescope (TMMT) is a fully robotic, 300mm telescope at Las Campanas Observatory (LCO), for which the nightly operation and data processing have been completely automated. Over the course of two years data were collected on 179 individual nights for our sample of the 55 RR Lyrae in the B, V, and IC broadband filters. Of these nights, 76 were under photometric conditions and calibrated directly. The 103 nonphotometric nights were roughly calibrated by using the default transformation equations, but only provide differential photometry relative to the calibrated frames. This resulted in 59698 final individual observations. Individual data points have a typical photometric precision of 0.02mag. The statistical error falls rapidly with hundreds of observations, with the zero-point uncertainties being the largest source of uncertainty in the final reported mean magnitude. To compare the results of our TMMT campaign to previous studies of these RR Lyrae (RRL) and to fill gaps in our TMMT phase coverage, we have compiled available broadband data from literature published over the past 30 years and spanning our full wavelength coverage (0.4 to 4.5μm) from the optical to mid-infrared. We have homogenized these diverse data sets to the following filter systems: Johnson UBV, Kron-Cousins RI, 2MASS J,H,Ks, and Spitzer [3.6], [4.5]. The All Sky Automated Survey (ASAS; http://www.astrouw.edu.pl/asas/) is a long-term project monitoring all stars brighter than V~14mag. The program covers both hemispheres, with telescopes at Las Campanas Observatory in Chile and Haleakala on Maui, both of which provide simultaneous I and V photometry. The GEOS RR Lyr Survey (http://www.ast.obs-mip.fr/users/leborgne/dbRR/grrs.html) is a long-term program utilizing TAROT (http://tarot.obs-hp.fr/) at Calern Observatory (Nice University, France). Annual data releases from this project add times for maximum light for program stars over the last year of observations. In addition to the large programs previously described, we use optical data from individual studies over the past 30 years (Barnes et al. 1992PASP..104..514B, Cacciari et al. 1987A&AS...69..135C, Skillen et al. 1993SAAOC..15...90S, Liu & Janes 1989ApJS...69..593L, Paczynski 1965AcA....15..115P, Jones et al. 1992ApJ...386..646J, Warren 1966MNSSA..25..103W, Fernley et al. 1989MNRAS.236..447F, Fernley et al. 1990MNRAS.242..685F, and Clementini et al. 2000AJ....120.2054C). Single-epoch photometry is available from 2MASS (Cutri et al. 2003, Cat. II/246) in J, H, and Ks. Data from Sollima et al. 2008 (Cat. J/MNRAS/384/1583), Liu & Janes 1989ApJS...69..593L, Barnes et al. 1992PASP..104..514B, and Fernley et al. 1993A&AS...97..815F, Skillen et al. 1989MNRAS.241..281S, Fernley et al. 1990MNRAS.242..685F, Fernley et al. 1989MNRAS.236..447F and Skillen et al. 1993MNRAS.265..301S are adopted. The mid-infrared [3.6] and [4.5] observations were taken using Spitzer/IRAC as part of the Warm-Spitzer Exploration Science Carnegie RR Lyrae Program (CRRP; PID 90002, Freedman et al. 2012sptz.prop90002F). WISE (Wright et al. 2010AJ....140.1868W; see also Cutri et al. 2012, Cat. II/311) or NEOWISE (Mainzer et al. 2011ApJ...731...53M, Mainzer et al. 2014, Cat. J/ApJ/792/30) photometry is available for each of our stars. (5 data files).

  11. Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial.

    Science.gov (United States)

    Vilgrain, Valérie; Pereira, Helena; Assenat, Eric; Guiu, Boris; Ilonca, Alina Diana; Pageaux, Georges-Philippe; Sibert, Annie; Bouattour, Mohamed; Lebtahi, Rachida; Allaham, Wassim; Barraud, Hélène; Laurent, Valérie; Mathias, Elodie; Bronowicki, Jean-Pierre; Tasu, Jean-Pierre; Perdrisot, Rémy; Silvain, Christine; Gerolami, René; Mundler, Olivier; Seitz, Jean-Francois; Vidal, Vincent; Aubé, Christophe; Oberti, Frédéric; Couturier, Olivier; Brenot-Rossi, Isabelle; Raoul, Jean-Luc; Sarran, Anthony; Costentin, Charlotte; Itti, Emmanuel; Luciani, Alain; Adam, René; Lewin, Maïté; Samuel, Didier; Ronot, Maxime; Dinut, Aurelia; Castera, Laurent; Chatellier, Gilles

    2017-12-01

    Sorafenib is the recommended treatment for patients with advanced hepatocellular carcinoma. We aimed to compare the efficacy and safety of sorafenib to that of selective internal radiotherapy (SIRT) with yttrium-90 ( 90 Y) resin microspheres in patients with hepatocellular carcinoma. SARAH was a multicentre, open-label, randomised, controlled, investigator-initiated, phase 3 trial done at 25 centres specialising in liver diseases in France. Patients were eligible if they were aged at least 18 years with a life expectancy greater than 3 months, had an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1, Child-Pugh liver function class A or B score of 7 or lower, and locally advanced hepatocellular carcinoma (Barcelona Clinic Liver Cancer [BCLC] stage C), or new hepatocellular carcinoma not eligible for surgical resection, liver transplantation, or thermal ablation after a previously cured hepatocellular carcinoma (cured by surgery or thermoablative therapy), or hepatocellular carcinoma with two unsuccessful rounds of transarterial chemoembolisation. Patients were randomly assigned (1:1) by a permutated block method with block sizes two and four to receive continuous oral sorafenib (400 mg twice daily) or SIRT with 90 Y-loaded resin microspheres 2-5 weeks after randomisation. Patients were stratified according to randomising centre, ECOG performance status, previous transarterial chemoembolisation, and presence of macroscopic vascular invasion. The primary endpoint was overall survival. Analyses were done on the intention-to-treat population; safety was assessed in all patients who received at least one dose of sorafenib or underwent at least one of the SIRT work-up exams. This study has been completed and the final results are reported here. The trial is registered with ClinicalTrials.gov, number NCT01482442. Between Dec 5, 2011, and March 12, 2015, 467 patients were randomly assigned; after eight patients withdrew consent, 237 were assigned to

  12. Surficial geologic map of the Mount Grace-Ashburnham-Monson-Webster 24-quadrangle area in central Massachusetts

    Science.gov (United States)

    Stone, Janet R.

    2013-01-01

    The surficial geologic map shows the distribution of nonlithified earth materials at land surface in an area of 24 7.5-minute quadrangles (1,238 mi2 total) in central Massachusetts. Across Massachusetts, these materials range from a few feet to more than 500 ft in thickness. They overlie bedrock, which crops out in upland hills and as resistant ledges in valley areas. The geologic map differentiates surficial materials of Quaternary age on the basis of their lithologic characteristics (such as grain size and sedimentary structures), constructional geomorphic features, stratigraphic relationships, and age. Surficial materials also are known in engineering classifications as unconsolidated soils, which include coarse-grained soils, fine-grained soils, and organic fine-grained soils. Surficial materials underlie and are the parent materials of modern pedogenic soils, which have developed in them at the land surface. Surficial earth materials significantly affect human use of the land, and an accurate description of their distribution is particularly important for assessing water resources, construction-aggregate resources, and earth-surface hazards, and for making land-use decisions. This work is part of a comprehensive study to produce a statewide digital map of the surficial geology at a 1:24,000-scale level of accuracy. This report includes explanatory text (PDF), quadrangle maps at 1:24,000 scale (PDF files), GIS data layers (ArcGIS shapefiles), metadata for the GIS layers, scanned topographic base maps (TIF), and a readme.txt file.

  13. Rootsi saamid võitlevad õiguse eest maale / Sarah Edmonds

    Index Scriptorium Estoniae

    Edmonds, Sarah

    2007-01-01

    Rootsi saamide parlamendil on 1. jaanuarist õigus määrata kohalikud piirid ja jagada abiraha loomasööda ostmiseks ja kompensatsioonide maksmiseks. Nüüd soovivad saamid maaga seotud küsimuste lahendamist. Lisa: Rootsi tõrjub põlisasukate konventsiooni

  14. Suurbritannia tutvustab end Paides / Sarah Squire ; interv. Signe Kalberg

    Index Scriptorium Estoniae

    Squire, Sarah

    2002-01-01

    Paides toimub Briti saatkonna, Briti Nõukogu Suurbritannia ja Euroopa päev. Suursaadik vastab küsimustele Euroopa päeva kohta 8. mail, Suurbritannia ja EL-i suhete kohta, oma diplomaatilise tegevuse kohta

  15. Adaptive sports ankle prosthetics. Interview by Sarah A. Curran.

    Science.gov (United States)

    Lyle, David K

    2012-09-01

    Participating in sport at all levels is gaining a dedicated following and this is also apparent in individuals with an amputation. Currently, there is a wide variety of ankle prostheses available which attempt to provide function, control, and comfort, as well as good aesthetic appeal. Participation in sport, however, increases the demands placed upon ankle prostheses. This can compromise function and performance, and constrain the opportunities of participation in various outdoor and water sports. In acknowledging this limitation and the need to develop more versatile ankle prostheses, this article introduces the evolution of a prototype ankle prosthesis referred to as "Adaptive Sports Ankle." The ankle prosthesis, which is compatible with any foot pyramid adapter, offers the same range of motion as the normal human ankle joint and is made up of components that are chemical and corrosion resistant. These design features that are specifically created to accommodate below-the-knee amputees provide an ideal prosthesis for those wishing to lead an active lifestyle and participate in aquatic (i.e. swimming, surfing, and scuba diving), snowboarding, and equestrian activities. Although it is acknowledged that there is a need to establish research on the Adaptive Sports Ankle, its introduction to the market will enhance and expand opportunities of those individuals with a lower limb amputation to lead an active and healthy lifestyle.

  16. Sarah was a butch: sexual identity, gender practices, and Sarah's place as mother in the Jewish National Pantheon.

    Science.gov (United States)

    Kalev, Henriette Dahan

    2012-01-01

    Three fields of discourse regarding a masculine-like woman connect at a point that the queer field calls intersex, medical practice calls a sexual disorder, and rabbinic literature terms aylonit. The queer discursive field focuses on the freedom to choose an identity, but not the freedom from choosing one. The medical field focuses on sexual practice as the source of determining "normal" sexuality. In the discursive field of Jewish law there are no demands, because the Halakhic authority determines gender identity on behalf of the individual, maintaining ambiguity. Copyright © Taylor & Francis Group, LLC

  17. Studio della convezione durante il monsone africano: osservazioni e modellazione della precipitazione e del ruolo della circolazione regionale sulla composizione atmosferica

    OpenAIRE

    Orlandi, Emiliano

    2010-01-01

    The improvement of knowledge and understanding of the West African Monsoon (WAM) is a fundamental scientific issue with implications on economy, health, water resources and food security in West African countries. In a region where agriculture is mainly rain fed, a delay in the rainy season onset or a dry year could compromise food and water security and lead to dearth conditions. The natural interannual and interseasonal variability of the WAM and the dramatic change from wet ...

  18. Sarah Zappulla Muscarà-Enzo Zappulla, Gabriele d'Annunzio ...

    African Journals Online (AJOL)

    User

    E fu D'Annunzio a curare il libretto della Figlia di Iorio per la musica di. Alberto Franchetti (Scala di Milano, 29 marzo 1906). Il volume offre dunque un panorama fitto di informazioni, commentate con rigore critico, storico e filologico, nel quale figurano sia il testo originale della tragedia sia le tre versioni dialettali: con un.

  19. Sarah Le Menestrel. La voie des Cadiens. Tourisme et identité en Louisiane.

    Directory of Open Access Journals (Sweden)

    Nathalie Dessens

    2006-03-01

    Full Text Available Cet ouvrage, publié dans la collection « Histoire et Société, Cultures Américaines », est une belle étude ethnologique du récent renouveau de la culture cadienne en Louisiane. L’introduction explique clairement les cadres méthodologiques de cette étude de terrain, menée au sein même de la communauté cadienne. Elle évoque aussi les divers problèmes inhérents à l’enquête anthropologique, entre autres celui du rôle et des implications du chercheur. Le corps de l’ouvrage se compose de trois parti...

  20. Sarah Kay, Terence Cave & Malcolm Bowie, eds. A Short History of French Literature

    Directory of Open Access Journals (Sweden)

    Anne-Marie SMITH-DI BIASIO

    2006-06-01

    Full Text Available At once kaleidoscopic and telescopic, the book presents three periods of French literature, the Middle Ages, the Early Modern and the Modern, in both overview and close-up. A triptych by three authors, each an eminent academic, and indeed emblematic specialist in their field, it condenses a remarkable amount of scholarship, close reading and critical practice. If three distinct voices emerge, they also converse, since there are echoes and overlaps between sections.This is a carefully crafted,...

  1. Sarah J. Hale High School Project SABER. ESEA Title VII. Final Evaluation Report, 1979-80.

    Science.gov (United States)

    New York City Board of Education, Brooklyn, NY. Office of Educational Evaluation.

    This is an evaluation of a Title VII Bilingual Program conducted at a New York City High School in 1979-80. The report contains information on the program goals and objectives, the school site, and the student characteristics. Aspects of the instructional component discussed include programming, mainstreaming, and program funding.…

  2. Ercole Patti, La cugina, a cura di Sarah Zappulla Muscarà, Casa de ...

    African Journals Online (AJOL)

    User

    asse, vero tronco portante di un frondoso rameggio, è la storia di Enzo e della cugina Agata. E questo si capisce fin dalle prime battute quando, incontratisi nella stanza del figlio dell'ingegnere, ossia di Enzo, cominciano i toccamenti e.

  3. Ischemic Stroke in Young Adults: Profile of SARAH Hospital Brasília From 2008 to 2012.

    Science.gov (United States)

    Montanaro, Vinícius V A; Freitas, Denise D S; Ruiz, Miguel C M; Cavalcanti, Eduardo B U; Marinho, Patricia B C; Freitas, Maria C D N B; Oliveira, Eleonora M J D

    2017-03-01

    The societal and economic impact of ischemic stroke in young adults is considerable. The etiological investigation of ischemic stroke in this population is also challenging. To describe the characteristics of young patients with ischemic stroke admitted to a neurological rehabilitation program in Brazil. This transversal retrospective study analyzed data from the electronic health records of 134 patients aged 18 to 45 years with ischemic stroke admitted from 2008 to 2012. The average patient age at the time of ictus was 33 years; 56% of the subjects were female, and 29.3% had undetermined etiologies of stroke, on the basis of both TOAST and SSS TOAST criteria. Further, 48.7% of the subjects had a known vascular risk factor, which was arterial hypertension in most cases. The results of thrombophilia testing were positive in 13.7% of patients, but in only 3.7% of patients, thrombophilia was determined to be the causal mechanism of the stroke. There was a significant association between thrombophilia and patent foramen ovale, but no significant association was found between thrombophilia and arterial dissection. Among the patients with artery dissections, 46% had a history of trauma, which was statistically significant. Etiological diagnosis of stroke in the young is challenging for clinicians. Hence, a more effective classification scheme, better investigative mechanisms, and correct determination of causal associations in ischemic stroke are needed. Thrombophilia screening should be performed in the presence of relevant clinical signs and/or family history.

  4. The medically examined applicant for private insurance and his/her right to informed consent: a comparative analysis / Sarah Defloor

    Index Scriptorium Estoniae

    Defloor, Sarah

    2011-01-01

    Tervisekindlustuse õiguslikud küsimused ja patsiendi õigused. Inimõiguste ja biomeditsiini konventsioon inimõiguste ja inimväärikuse kaitse bioloogia ja arstiteaduse rakendamisel (vastu võetud 04.04.1997)

  5. Euroopa püüab toime tulla idatööliste marsiga läände / Sarah Laitner, Stefan Wagstyl

    Index Scriptorium Estoniae

    Laitner, Sarah

    2006-01-01

    Mitmed EL-i nn. vanad riigid kõhklevad, kas kaotada piirangud Ida-Euroopa tööjõule. Briti valitsuse väitel on riigi majandus tööturu piirangu kaotamisest kasu saanud, samas on suurenenud noorte pikaajaline töötus. Ida-Euroopas on aga mõnes valdkonnas tekkinud tööjõupuudus. Lisa: Iiri pelgab olukorda tööjõuturul. Tabel: Riikide suhtumine tööjõu vaba liikumise piirangutesse

  6. The Italian translation and adaptation of The Service Standards for Therapeutic Communities for Children and Young People 2nd Edition (by John O’Sullivan & Sarah Paget

    Directory of Open Access Journals (Sweden)

    Simone Bruschetta

    2014-09-01

    Full Text Available This work presents the adaptation to the Italian context of the "Community of Communities standards" (by O'Sullivan & Paget. We have tried to remain as faithful as possible to the Community of Communities clinical sense, organizational and psychodynamic statements, while still trying to locate the huge experience behind the philosophy of the therapeutic community in the socio-political Italian context. In Italy, health work is heavily regulated within public institutions with their own competences that cover specific administrative services, different types of users and particular territorial areas. Especially in the health services to childhood, the institutional and legal powers that law administration attaches to families, public schools, social services of territorial competence and local health authorities, require an articulated taking charge, involving all these institutions, which is often added to the Juvenile Court of Justice, with its almost limitless powers of decree. For this reason, in chapter 5.4. of list (collaborating, we proposed two additional items (5.4.3 and 5.4.4, to 5.4.1 and 5.4.2, to better define the design mode of the clinical taking care by communities in Italian context and culture. These are the only items added to the text.Keywords: Therapeutic Community, Children, Yang People, Service Standards, Clinical Quality

  7. Women as Members of Communities. Third Grade Social Studies: Abigail Adams, Sarah Winnemucca, Helen Keller, Shirley Chisholm, March Fong Eu, [and] Carmen Delgado Votaw.

    Science.gov (United States)

    National Women's History Project, Santa Rosa, CA.

    Part of the National Women's History Project funded to promote the study of women in history, this unit will help third grade students learn about women's contributions to U.S. society. Equity cannot be achieved until equality is expected and until the contributions of all women are understood and accepted as a simple matter of fact. The unit…

  8. Sarah's birth. How the medicalisation of childbirth may be shaped in different settings: Vignette from a study of routine intervention in Jeddah, Saudi Arabia.

    Science.gov (United States)

    Scamell, Mandie; Altaweli, Roa; McCourt, Christine

    2017-02-01

    The expansion of the medicalisation of childbirth has been described in the literature as being a global phenomenon. The vignette described in this paper, selected from an ethnographic study of routine intervention in Saudi Arabian hospitals illustrates how the worldwide spread of the bio-medical model does not take place within a cultural vacuum. To illuminate the ways in which the medicalisation of birth may be understood and practised in different cultural settings, through a vignette of a specific birth, drawn as a typical case from an ethnographic study that investigated clinical decision-making in the second stage of labour in Saudi Arabia. Ethnographic data collection methods, including participant observation and interviews. The data presented in this paper are drawn from ethnographic field notes collected during field work in Saudi Arabia, and informed by analysis of a wider set of field notes and interviews with professionals working in this context. While the medicalisation of care is a universal phenomenon, the ways in which the care of women is managed using routine medical intervention are framed by the local cultural context in which these practices take place. The ethnographic data presented in this paper shows the medicalisation of birth thesis to be incomplete. The evidence presented in this paper illustrates how local belief systems are not so much subsumed by the expansion of the bio-medical model of childbirth, rather they may actively facilitate a process of localised reinterpretation of such universalised and standardised practices. In this case, aspects of the social and cultural context of Jeddah operates to intensify the biomedical model at the expense of respectful maternity care. In this article, field note data on the birth of one Saudi Arabian woman is used as an illustration of how the medicalisation of childbirth has been appropriated and reinterpreted in Jeddah, Saudi Arabia. Copyright © 2016 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  9. “Knaller-Sex für alle”: Popfeminist Body Politics in Lady Bitch Ray, Charlotte Roche, and Sarah Kuttner

    OpenAIRE

    Carrie Smith-Prei

    2011-01-01

    Germany has seen a recent upsurge in publications proclaiming that feminism is again an urgent matter for a new generation of women. Faced with the reactionary demography debate and the hegemony of second-wave feminism, young writers, musicians, journalists, and critics call for new models of feminism relevant to women today. As one of these viable models, popfeminism draws on dominant trends in mass culture, on pop’s forty-year history as a cultural prefix in Germany, and on traditional femi...

  10. Seasonal Workers in Mediterranean Agriculture: the social costs of eating fresh, dirigé par Jörg Gertel et Sarah Ruth Sippel (2014)

    OpenAIRE

    Perrotta, Domenico

    2014-01-01

    GERTEL J. and SIPPEL S.R. (eds.) (2014), Seasonal Workers in Mediterranean Agriculture. The social costs of eating fresh, Routledge, [London] 294p. Cet ouvrage collectif a trois grands motifs d’intérêt. En premier lieu, en recueillant un grand nombre de recherches empiriques réalisées dans différents domaines disciplinaires, il constitue la première tentative en langue anglaise de systématiser ce que la science sociale a produit au cours des quinze dernières années par rapport au thème des ou...

  11. Là que la mort vit. Sur les théâtres de Jon Fosse, Sarah Kane et Rodrigo García

    NARCIS (Netherlands)

    Rafis, V.

    2012-01-01

    Should theatre come about through the meeting of printed matter on paper and of a place in which to execute it, then death – offering neither the ability to say nor to do – can only ever appear foreign to it. Deprived of words and of images, and shrouded in both dissolution and silence, this death

  12. Violence, xenophobia and crime

    African Journals Online (AJOL)

    prominent domestic and international media coverage of threats of xenophobic violence, predicted to start ..... 2010; V Igglesden, T Monson et al., Humanitarian. Assistance to ... Johannesburg, CoRMSA, Crisis in Zimbabwe. Coalition, FMS ...

  13. The Density-wave Theory and Spiral Structures by Looking at Spiral Arms through a Multi-wavelength StudyHamed Pour-Imani1,2, Daniel Kennefick1,2, Julia Kennefick1,2, Mohamed Shameer Abdeen1,2, Eric Monson1,2, Douglas W. Shields1,2, B. L. Davis31Department of Physics, University of Arkansas, Fayetteville, AR 72701, USA2Arkansas Center for Space & Planetary Sciences, Univ. of Arkans

    Science.gov (United States)

    Pour-Imani, Hamed; Kennefick, Daniel; Kennefick, Julia; Shameer Abdeen, Mohammad; Monson, Erick; Shields, Douglas William; Davis, Benjamin L.

    2018-01-01

    The density-wave theory of spiral structure, though first proposed as long ago as the mid-1960s by C.C. Lin and F. Shu, continues to be challenged by rival theories, such as the manifold theory. One test between these theories which has been proposed is that the pitch angle of spiral arms for galaxies should vary with the wavelength of the image in the density-wave theory, but not in the manifold theory. The reason is that stars are born in the density wave but move out of it as they age. In this study, we combined large sample size with a wide range of wavelengths to investigate this issue. For each galaxy, we used wavelength FUV151nm, U-band, H-alpha, optical wavelength B-band and infrared 3.6 and 8.0μm. We measured the pitch angle with the 2DFFT and Spirality codes (Davis et al. 2012; Shields et al. 2015). We find that the B-band and 3.6μm images have smaller pitch angles than the infrared 8.0μm image in all cases, in agreement with the prediction of the density-wave theory. We also find that the pitch angle at FUV and H-alpha are close to the measurements made at 8.0μm. The Far-ultraviolet wavelength at 151nm shows very young, very bright UV stars still in the star-forming region (they are so bright as to be visible there and so short-lived that they never move out of it). We find that for both sets of measurements (2dFFT and Spirality) the 8.0μm, H-alpha and ultraviolet images agree in their pitch angle measurements, suggesting that they are, in fact, sensitive to the same region. By contrast, the 3.6μm and B-band images are uniformly tighter in pitch angle measurements than these wavelengths, suggesting that the density-wave picture is correct.

  14. Effects of Absence and Cognitive Skills Index on Various Achievement Indicators. A Study of ISTEP Scores, Discrepancies, and School-Based Math and English Tests of 1997-1998 Seventh Grade Students at Sarah Scott Middle School, Terre Haute, Indiana.

    Science.gov (United States)

    Davis, Holly S.

    This study examines the correlation between absence, cognitive skills index (CSI), and various achievement indicators such as the Indiana Statewide Testing for Educational Progress (ISTEP) test scores, discrepancies, and school-based English and mathematics tests for 64 seventh-grade students from one middle school. Scores for each of the subtests…

  15. Sarah Dellmann: Widerspenstige Körper. Körper, Kino, Sprache und Subversion in Tod Brownings FREAKS und Filmen mit Lon Chaney. Marburg: Schüren Verlag 2009.

    Directory of Open Access Journals (Sweden)

    Fabian Tietke

    2010-11-01

    Full Text Available Im vorliegenden Band werden Filme des in den 1920er und 1930er Jahren sehr erfolgreichen Regisseurs Tod Browning analysiert, insbesondere sein heute bekanntestes Werk Freaks. Mithilfe historischer Kontextualisierungen und eines filmwissenschaftlichen Instrumentariums untersucht Dellmann die These, dass sich in diesem Werk Spuren eines heute verloren gegangenen Körperverständnisses finden lassen – vor allem andere Repräsentationen von Behinderung und behinderten männlichen Körpern.The present anthology analyzes several movies of the director Tod Browning (who was very successful in the 1920s and 1930s, particularly the movie Freaks which, today, is his most well-known work. Using historical contextualizations and a Film Studies background, Dellmann explores the thesis that this work shows traces of an understanding of the body that today no longer exist, above all the representation of disabilities and disabled male bodies.

  16. Paclitaxel/carboplatin with or without sorafenib in the first-line treatment of patients with stage III/IV epithelial ovarian cancer: a randomized phase II study of the Sarah Cannon Research Institute

    International Nuclear Information System (INIS)

    Hainsworth, John D; Thompson, Dana S; Bismayer, John A; Gian, Victor G; Merritt, William M; Whorf, Robert C; Finney, Lindsey H; Dudley, B Stephens

    2015-01-01

    This trial compared the efficacy and toxicity of standard first-line treatment with paclitaxel/carboplatin versus paclitaxel/carboplatin plus sorafenib in patients with advanced ovarian carcinoma. Patients with stage 3 or 4 epithelial ovarian cancer with residual measurable disease or elevated CA-125 levels after maximal surgical cytoreduction were randomized (1:1) to receive treatment with paclitaxel (175 mg/m 2 , 3 h infusion, day 1) and carboplatin (AUC 6.0, IV, day 1) with or without sorafenib 400 mg orally twice daily (PO BID). Patients were reevaluated for response after completing 6 weeks of treatment (two cycles); responding or stable patients received six cycles of paclitaxel/carboplatin. Patients receiving the sorafenib-containing regimen continued sorafenib (400 PO BID) for a total of 52 weeks. Eighty-five patients were randomized and received treatment.Efficacy was similar for patients receiving paclitaxel/carboplatin/sorafenib versus paclitaxel/carboplatin: overall response rates 69% versus 74%; median progression-free survival 15.4 versus 16.3 months; 2 year survival 76% versus 81%. The addition of sorafenib added substantially to the toxicity of the regimen; rash, hand–foot syndrome, mucositis, and hypertension were significantly more common in patients treated with sorafenib. The addition of sorafenib to standard paclitaxel/carboplatin did not improve efficacy and substantially increased toxicity in the first-line treatment of advanced epithelial ovarian cancer. Based on evidence from this study and other completed trials, sorafenib is unlikely to have a role in the treatment of ovarian cancer

  17. NREL Manager Elected to IREC Board of Directors

    Science.gov (United States)

    Manager Elected to IREC Board of Directors For more information contact: Sarah Holmes Barba, 303 -275-3023 email: Sarah Barba Golden, Colo., May 14, 2001 - David Warner, manager of the Information and

  18. 75 FR 7043 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... Valley, AL 01/25/10 01/15/10 Office (Comp). 73343 Convergys, IMG (Wkrs)...... Lake Mary, FL......... 01... Tardy-Conners Group, LLC Monson, ME 01/26/10 01/22/10 (Wkrs). 73360 Mann-Hummel Advanced Louisville, KY...

  19. Attention-Deficit/Hyperactivity Disorder-Related Impulsivity and Cyberbullying in Social Media.

    Science.gov (United States)

    Reilly, Marie; Fogler, Jason; Selkie, Ellen; Augustyn, Marilyn

    2016-01-01

    Sarah is a 13-year-old eighth grader who was recently diagnosed for the first time with attention-deficit/hyperactivity disorder (ADHD)-inattentive type, and the family elected to treat her with behavioral interventions to help her organization and attention. She had struggled with distractibility and disorganization since the fourth grade. At home, Sarah's mother described her as "spacey" and unable to complete the morning routine without constant supervision. Over time, her mother observed that it seemed as if Sarah had given up on school.As Sarah became an adolescent, her self-esteem suffered because of her academic struggles, and she placed increasing emphasis on her appearance, including focus on remaining thin and refusing to leave the house without makeup. It was in this context that Sarah recently posted photographs of herself in various stages of undress and/or drinking alcohol on Snapchat, a photograph-sharing application in which users can send "snaps"-photographs that disappear soon after opening. However, snap recipients can take a screenshot or photograph of the snap, thereby saving the image. For unknown reasons, Sarah's close female friend took screenshots of these provocative photographs and sent them to their classmates and Sarah's older brother.Sarah's family contacted the police and has been working with her school to address this incident. This experience resulted in significant family stress and distrust of Sarah. For example, her mother took away her cell phone and laptop and has "grounded her" for a month from all out of school activities.Sarah's family seeks guidance regarding teaching Sarah about using social media responsibly and preventing this from happening again. Sarah's mom comes to your urgent care session asking for help because she does not feel that Sarah has "learned her lesson." What would you do next?

  20. Suursaadikud Keskerakonna peakorteris

    Index Scriptorium Estoniae

    2001-01-01

    Ameerika Ühendriikide suursaadik Melissa Wells kohtus Edgar Savisaare, Peeter Kreitzbergi ja Sven Mikseriga. Kommentaarid suursaadik Melissa Wells'ilt. Suurbritannia suursaadik Sarah Squire Keskerakonna peakorteris

  1. 76 FR 28022 - Increasing Market and Planning Efficiency Through Improved Software; Notice of Technical...

    Science.gov (United States)

    2011-05-13

    ... advancements related to these technologies, the potential benefits or costs associated with these advancements... further information about these conferences, please contact: Sarah McKinley (Logistical Information...

  2. Staarkleidid / Lee Hanael

    Index Scriptorium Estoniae

    Hanael, Lee

    2008-01-01

    10 maailma kuulsamat kleiti kuulusid Marilyn Monroele, Audrey Hepburnile, printsess Dianale, Vivien Leighle, Tina Turnerile, Julia Robertsile, Liz Hurleyle, Sarah Jessica Parkerile, Keira Knightleyle, Jacqueline Kennedyle

  3. Virtual Racism Rears its Head: Uncovering Librarian Bias in E-mail Reference Services. A review of: Shachaf, Pnina, and Sarah Horowitz. “Are Virtual Reference Services Color Blind?” Library & Information Science Research 28.4 (Sept. 2006: 501‐20.

    Directory of Open Access Journals (Sweden)

    Wendy Furlan

    2007-06-01

    Full Text Available Objective – To examine whether librarians provide equitable virtual reference services to diverse user groups.Design – Unobtrusive method of defined scenarios submitted via e-mail.Setting – Twenty‐three Association of Research Libraries (ARL member libraries from across the United States. All ARL member libraries were invited to participate, with the 23 acceptances providing 19% participation.Subjects – Anonymous librarians from the 23 participating libraries’ virtual e‐mail reference services. Up to 6 librarians from each library may have been involved. Six fictitious personas were developed to represent particular ethnic or religious groups, whereby the ethnic or religious affiliation was only indicated by the name chosen for each user and the correspondinge‐mail address. Names were selected from lists of names or baby names available online: Latoya Johnson (African‐American, Rosa Manuz (Hispanic, Chang Su (Asian ‐Chinese, Mary Anderson(Caucasian/Christian, Ahmed Ibrahim (Muslim, and Moshe Cohen(Caucasian/Jewish. These personas were used to submit reference queries via e‐mail to the virtual reference services taking part in the study.Methods – Five different types of reference queries were developed for use in this study. Three were based on prior published research as they were deemed to be answerable by the majority of libraries. They included a dissertation query, a sports team query, and a population query all designed to be tailored to the target institution. The other 2 queries were developed with participating institutions’ virtual reference guidelines in mind, and were thought to not be answered by the target institutions when submitted by unaffiliated users. They consisted of a subject query on a special collection topic that asked for copies of relevant articles to be sent out, and an article query requesting that a copy of a specific article be e‐mailed to the patron. The study was conducted over a 6 week period beginning the second week of September, 2005. Each week, 1 fictitious persona was used to e‐mail a reference query to the virtual reference service of each of the 23 participating institutions. Five of each type of query were sent by each persona. During September and October 2005, a total of 138 queries were sent. Each institution received a different query for each of the first 5 weeks, and in the sixth week they received a repeat of a previous request with details of title or years altered. All other text in every request sent was kept consistent. Each institution only received 1 request from each persona during the study. In order to eliminate any study bias caused by an informed decision regarding the order in which personas were used, they were randomly arranged (alphabetically by surname. Furthermore, to avoid suspicions from responding librarians, queries were emailed on different days of the week at different times. This created some limitations in interpretating response times as some queries were submitted on weekends. All queries were analysed by Nvivo software in order to identify attributes and patterns to aid qualitative analysis. Each transaction (a single query and any related responses was classified according to 12 attributes and 59 categories based on various associations’ digital reference guidelines. Transactions were coded and then 10% re‐coded by a different coder. This led to the clarification and refinement of the coding scheme, resulting in the number of categories used being reduced to 23. Coding was then performed in 3 iterations until 90%agreement between the 2 coders was reached. The final inter‐coder reliability was 92%. The study did not support cross tabulation among user groups on most content categories due to the small sample size.Main results – Response times varied greatly between users. Moshe (Caucasian/Jewish received an average turn‐around of less than a day. At the other end of the spectrum, Ahmed’s (Muslimresponses took an average of 3.5 days. Both Ahmed and Latoya (African‐American sent queries which took over 18 days to receive a response. The length (number of words of replies also indicated a differing level of service with Mary (Caucasian/Christianand Moshe receiving far lengthier responses than the other 4 personas. Number of replies (including automatic replies was examined in comparison with the number of replies which answered the question, and again indicated Mary and Moshe were receiving a better level of service. The way in which the user was addressed by the librarian was examined as another measure of service, i.e. first name, full name, honorific. This again mirrored the low level of service received by Ahmed. The professional endings used by librarians in their replies also reinforced the high quality of service received by Moshe across other categories. Results for Rosa (Latino and Chang (Asian ‐Chinese were average for most categories presented.Conclusion – In this study, a discriminatory pattern was clearly evident, with the African‐American and Muslim users receiving poor levels of service from virtual reference librarians across all dimensions of quality evaluated. The Caucasian (Christian and Jewish users also noticeably received the best level of service. It is noted, however, that the sample size of the study is not large enough for generalisations to be drawn and that future, more statistically significant studies are warranted. Many other questions are raised by the study for possible future research into racism exhibited by library staff and services.

  4. Purchase of Journal Portfolios by Research Libraries is not Cost-Effective and May Lead to Normalization of Collections. A Review of: Murphy, Sarah Ann. “The Effects of Portfolio Purchasing on Scientific Subject Collections.” College & Research Libraries July 2008: 332-40.

    Directory of Open Access Journals (Sweden)

    Stephanie Walker

    2009-03-01

    Full Text Available Objectives – To determine whether the purchase of journal portfolios (i.e., packages of journals purchased as a group from publishers, such as Elsevier’s ScienceDirect from publishers is an effective means of meeting research needs for faculty in the life, medical, physical, and applied sciences, and to determine the effects of such purchases on research library collections.Design – Citation analysis.Setting – Ohio State University libraries in the life, medical, physical, and applied sciences.Subjects – A total of 253,604 citations from 6,815 articles published between the years 2003 and 2005 by Ohio State University faculty in the life, medical, physical, and applied sciences were analyzed using the Bradford distribution (an explanation of the Bradford Distribution is provided later in this review.Methods – Using ISI’s Science Citation Index,the author generated a list of articles published by Ohio State University (OSU faculty in the life, medical, physical, and applied sciences between the years 2003 and 2005. The author then assigned each article to a specific discipline, according to the OSU College of the first OSU author listed. For example, if an article was written by several co-authors, and the first OSU author listed was a faculty member in OSU’s College of Dentistry, the article would be designated a Dentistry article. Multi-disciplinary works were assigned to the college of the first OSU author listed. (The OSU Colleges considered to be part of the study were the College of Biological Sciences; the College of Dentistry; the College of Engineering; Food, Agriculture, and Environmental Sciences; the College of Mathematical and Physical Sciences; the College of Medicine; the College of Optometry; the College of Pharmacy; and the College of Veterinary Medicine. Books, conference proceedings, theses, and other non-journal materials were excluded from the set of citations considered. Next, the author pulled journal citations from each article, again utilizing Science Citation Index. The references were analyzed to determine the number of times each individual journal had been cited. The author then created a list of journals which had been cited in articles by OSU faculty in the various colleges, grouped by college. The journals were arranged in descending order, according to the number of times each journal had been cited. Thus there would be, for example, a list of all journals cited in articles published by faculty members in the OSU College of Dentistry between 2003 and 2005.Most journals had been cited only once over the three-year period. A total of 2,407 journal titles were cited 10 or more times. In total, the author analyzed 253,604 citations from 6,815 articles. A Bradford distribution of journal citations was calculated, and journals were divided into three categories. The three categories were called Zones 1, 2, and 3, with Zone 1 being corej ournals for the faculty, Zone 2 being more secondary titles, and Zone 3 being those cited least frequently. For those not familiar with this type of analysis, a definition of Bradford’s law is available on the U.S. National Institute for Standards and Technology website. It is included here for ease of reference: “Journals in a field can be divided into three parts, each with about one-third of all articles: 1 a core of a few journals; 2 a second zone, with more journals ;and 3 a third zone, with the bulk of journals. The number of journals is 1:n:n². Note that Bradford formulated his law after studying a bibliography of geophysics, covering 326 journals in the field. He discovered that 9 journals contained 429 articles, 59 contained 499 articles, and 258 contained 404 articles. Although Bradford's Law is not statistically accurate, librarians commonly use it as a guideline” (Black. The author then determined how the OSU Libraries purchased access to each title. The three options analyzed were: 1 through OHIOLink (through which OSU Libraries purchase the bulk of the journal portfolios to which they subscribe,2 through the independent purchase of an electronic subscription, or 3 through the independent purchase of a print subscription. The cost for each title was calculated by taking the amount paid for OHIOLink subscriptions and removing the cost of non-scientific journals from the total amount. Pricing for the non-scientific journals was obtained using EBSCO’s Librarian’s Handbook 2006-2007 and Ulrich’s Periodical Directory. To account for inflation, any 2007 prices were adjusted by 6. The above activities were designed to calculate both the cost of each title as purchased through OHIOLink, and what the OSU Libraries would have paid for each individual title if it had been purchased separately.Main Results – Of all journals cited by OSU faculty in the life, medical, physical, and applied sciences during the years studied, only 7% were available in print format only. The percentage of cited journal titles that were included in portfolio purchases varied considerably across the colleges. The college for which the greatest percentage of cited journals were obtained via OHIOLink was the College of Mathematical and Physical Sciences; 85.7% of journals cited by this College were purchased via OHIOLink. Overall figures for the cited journals analyzed were as follows: 52.0% were purchased via OHIOLink portfolio purchases, and 26.3% were purchased individually in electronic format by the OSU Libraries. Of all journals listed in Zone 1 (those designated as “core journals” for the fields in question,100% had electronic versions, though OSU Libraries continued to subscribe to the print version in addition to the electronic version for five titles, due to embargoes of 4-12 months in the electronic subscriptions. In terms of how the Zone 1 journals were acquired, 35.5% were purchased via OHIOLink as part of a portfolio purchase, and 62.2% were individually purchased. For the College of Biological Sciences; the College of Food, Agricultural, and Environmental Sciences; the College of Medicine; the College of Nursing; the College of Pharmacy; and the College of Veterinary Medicine, fewer than 40% of the Zone 1 (core, most highly cited titles for their disciplines were purchased via OHIOLink. For the Collegeo f Mathematical and Physical Sciences, 75.5% of Zone 1 titles were purchased via OHIOLink. This figure was 60.5% in the College of Engineering. By contrast, over 50% of the titles in Zone 1 for the Colleges of Dentistry, Nursing, Pharmacy, and Veterinary Medicine were purchased individually, and not via portfolio purchases from OHIOLink. The author notes that in these fields, the majority of research is published in journals from professional societies or smaller publishers, which have neither the high profile nor the market that some journals in other fields have, and thus are frequently not included in portfolios available via consortia such as OHIOLink. The author also provides a numerical breakdown, showing exactly how many titles in each of Zones 1, 2, and 3 were purchased via OHIOLink, how many were purchased directly by OSU in electronic form, and how many were purchased in print form, for each college and for all colleges combined. For all colleges combined, the overall results are as follows: Zone 1 included 45 cited journal titles. Of these, 16 were purchased via OHIOLink, 28 were purchased in electronic format directly by OSU, none were purchased in print, and one was considered “Other” (not at OSU, ceased, or cancelled. Zone 2 included 299 cited journal titles. Of these, 167 were purchased via OHIOLink, 109 were purchased in electronic format directly by OSU, 13 were purchased in print, and 10 fell under “Other”. Zone 3 included 2,063 cited journal titles. Of these, 1,068 were purchased via OHIOLink, 497 were purchased in electronic format directly by OSU, 155 were purchased in print, and 343 fell under “Other”. The author also provides a list of the top 50 journals cited, including the number of citations linked to each title and how the title was purchased. Of the top 50 journals, 32 were purchased directly by OSU Libraries in electronic format, and only 18 were purchased via OHIOLink. Interestingly, however, 70% of OSU Libraries’ total expenditures on titles in the life, medical, physical, and allied sciences are devoted to OHIOLink. The author notes that if OSU had not had OHIOLink, they would have paid 61.4% more to directly purchase the journals cited in this analysis which they currently obtain by portfolio purchases. However, if they purchased only those titles which the faculty in question had cited 10 or more times, the cost would be 30% more. If they purchased only the titles which had been cited 15 or more times, OSU would only have paid an 8.9% premium to buy the titles directly from the publisher rather than through OHIOLink.Conclusion – As the author points out, her findings raise the question as to whether the large amount of content provided by buying into the “Big Deal” portfolio purchases (as they are frequently called is really worth it for OSU Libraries. The author notes that other articles have asserted that portfolio purchases form a significant barrier to libraries wishing to purchase individual titles, as the amount spent on portfolio purchases can limit a library’s financial flexibility. Even when other individual titles may more closely meet faculty needs, it can be difficult to justify cancelling portfolio purchases that offer a larger number of journals in the field. The advantages and disadvantages of portfolio purchasing at Ohio State University Libraries are clear from the author’s research: while some fields are well-served by portfolio purchases, others are not, with large percentages of the journals which are most important in their fields not being available through such portfolios. Furthermore, due to the percentage of the OSU Libraries’ budget dedicated to OHIOLink portfolio purchases, flexibility to purchase titles not in portfolios is indeed limited. The author’s pricing calculations lead to the conclusion that OSU Libraries pay between an 8.9%-30.0% premium to maintain access to 3,813 titles (75.4% which were cited fewer than 10 times over the three year period between 2003 and 2005. The author concludes that the premium paid to access over three-quarters of the journals available in portfolios should be reconsidered, as they are relatively infrequently used and thus may not be meeting faculty research needs. The author recommends that large research libraries(including OSU Libraries consider a return to à la carte purchasing. Additionally, the author notes that purchase of portfolios by a large percentage of research libraries may lead to normalization of library collections and loss of the ability to support non-commercial publishers who publish strong research in specialized fields.

  5. Purchase of Journal Portfolios by Research Libraries is not Cost-Effective and May Lead to Normalization of Collections. A Review of: Murphy, Sarah Ann. “The Effects of Portfolio Purchasing on Scientific Subject Collections.” College & Research Libraries July 2008: 332-40.

    OpenAIRE

    Stephanie Walker

    2009-01-01

    Objectives – To determine whether the purchase of journal portfolios (i.e., packages of journals purchased as a group from publishers, such as Elsevier’s ScienceDirect) from publishers is an effective means of meeting research needs for faculty in the life, medical, physical, and applied sciences, and to determine the effects of such purchases on research library collections.Design – Citation analysis.Setting – Ohio State University libraries in the life, medical, physical, and applied scienc...

  6. Evidence Based Research Activities, Interests and Opportunities Exist for Practitioners in all Library Sectors in the British Isles. A review of: McNicol, Sarah. “Is Research an Untapped Resource in the Library and Information Profession?” Journal of Librarianship and Information Science 36.3 (September 2004:119-26.

    Directory of Open Access Journals (Sweden)

    Julie McKenna

    2006-03-01

    Full Text Available Objective – To scope the range, nature and challenges of present, planned and future research by practitioners within libraries in the British Isles. Design – A series of survey questionnaires sent by mail. Setting – Public, academic, health, special and school libraries of the British Isles. Subjects – A total of 2384 questionnaires were sent out and 334 responses were received. 62 academic libraries, 83 health libraries, 78 public libraries, 63 school libraries and 48 special libraries participated in the study. Methods – This study was undertaken in 2003 by a research team at the University of Central England. Survey questionnaires were sent by mail to library directors in all public library authorities, academic libraries, health libraries and special libraries in England, Wales, Scotland, Northern Ireland and the Republic of Ireland. In addition, questionnaires were sent to the librarians in all state and independent schools within a sample of nine local education authorities. Each participant was asked to identify past and future research issues of interest and the barriers to research practice within their library. Research was defined to include work on both externally funded and inhouse projects and examples of the types of activities that this might include were provided. Main results – Half the respondents reported that they had been involved in some form of research in the past two years, with the lowest level of involvement from school libraries and the highest in public libraries. Generally, only the library directly involved in conducting the research made use of the findings and a gap in the dissemination of results was identified across sectors. User surveys were the most common form of research undertaken across libraries and slightly fewer respondents intended to carry out research in the coming twelve months than had in the past (the area most commonly mentioned was user surveys. Information and communications technology (ICT was an area of planned future research in all libraries, as were user needs and user behaviour. The most frequently cited barriers to research activity across all sectors were lack of time and financial resources. Staff skills and the lack of focus on practical problems to solve were indicated as a barrier in health, public and academic libraries. Libraries reported a range of common uses for the research findings including: informing strategic and service planning; providing benchmarking data and measuring the effectiveness of services; identification of marketing and public relations opportunities; discovery of staff training needs; and use of the results to demonstrate the value of libraries to funding bodies. Conclusion – This study provides insight into practitioner‐focused areas of research interest and possible areas for future investigation. As the author reports in her conclusion, the survey results cannot be considered representative of the wider population. Since research interests often overlap, a sector wide or cross‐sectoral research approach should be considered to allow library staff to identify and resolve common problems. Wide dissemination of research results within the practitioner community would be of benefit to all. Greater communication between practitioner and information science communities is also encouraged, as these communities’ work is mutually beneficial.

  7. Libraries Demonstrate Low Adherence to Virtual Reference Service Guidelines. A Review of: Shachaf, Pnina, and Sarah M. Horowitz. “Virtual Reference Service Evaluation: Adherence to RUSA Behavioral Guidelines and IFLA Digital Reference Guidelines.” Library & Information Science Research 30.2 (2008: 122-37.

    Directory of Open Access Journals (Sweden)

    Elise Cogo

    2009-06-01

    Full Text Available Objectives – This study evaluates the level to which virtual (asynchronous e-mail reference services adhere to professional guidelines. Specifically, it addresses the following research questions:1 To what extent do virtual reference services adhere to the American Library Association (ALA Reference and User Services Association (RUSA and the International Federation of Library Associations (IFLA guidelines?2 How does the level of adherence to RUSA or IFLA guidelines vary based on request type, user name, and institution?3 Is there a correlation between outcome measures of reference transactions (accuracy, completeness, and satisfaction and the level of adherence to RUSA or IFLA guidelines?Design – Unobtrusive evaluation of researcher-generated queries.Setting – Fifty-four academic libraries in North America.Subjects – A total of 324 queries were sent to the 54 libraries, with each library receiving six different types of requests from six different user names.Methods – Researchers developed two coding schemes for the guidelines (34 codes and 12 attributes for the RUSA guidelines and 33 codes and 10 attributes for the IFLA guidelines. Each of the six user names used represented an ethnic and/or religious group identity: Mary Anderson (Caucasian, Christian, Moshe Cohen (Caucasian, Jewish, Ahmed Ibrahim (Arab, Latoya Johnson (African American, Rosa Manuz (Hispanic, and Chang Su (Asian. The six request types were designed so that three would be answered (questions 1-3 and three would be out of scope and not answered (questions 4-6. The following queries were sent, individualized for each institution: 1 Dissertation query; 2 Sports team query; 3 Population query; 4 Subject query; 5 Article query; 6 Request for a PDF copy. The 324 queries were uploaded into NVivo 2 software, and all e-mail transactions were coded and analyzed.Main Results – Analysis of the 324 transactions from 54 libraries showed the following results:1 Low levels of adherence to both sets of guidelines;2 Varied levels of adherence based on request types and user names on both sets of guidelines;3 Variation in institutional rank according to different sets of guidelines;4 No correlation between user satisfaction and adherence to either set of guidelines.Conclusion – This study suggests that higher levels of virtual reference service effectiveness could be achieved by automatically integrating some less observed behaviours (e.g., thank you notes into replies sent to users and by increasing librarians’ awareness of professional guidelines through training and detailed institutional policies. The authors also suggest that librarians should be aware of their tendencies to react differently to different user groups, and that administrators can facilitate this by providing diversity workshops.

  8. Bringing Bike Share to a Low-Income Community

    Centers for Disease Control (CDC) Podcasts

    This podcast is an interview with Sarah Kretman Stewart, MPH, MEd, Healthy Living Minneapolis Project Specialist at the Minneapolis Health Department. In this program, Sarah talks about the impact a bike share program had on the low-income town of Near North, Minnesota.

  9. 07 Smith 02.pmd

    African Journals Online (AJOL)

    Owner

    23 Jun 2009 ... Londen: W.W. Norton & Company, 514–22,. Goodwin, Sarah Webster. 1993. Romanticism and the ghost of prostitution: Freud, Maria, and “Alice. Fell”, in Goodwin, Sarah Webster & Bronfen, Elisabeth (reds.) Death and Representation. Baltimore en Londen: The John Hopkins University Press, 152–73.

  10. Zhit v televizore opasnei vsehh boleznei

    Index Scriptorium Estoniae

    2004-01-01

    Briti teadlaste (King's College) Tim Crayford'i, Richard Hooper'i ja Sarah Evans'i poolt läbi viidud uurimusest, milles nad tegid statistikat teleseriaalide kangelaste surmapõhjuste, sünnituste, psüühhiliste häirete kohta. Kommentaar ka arst Sarah Clement'ilt

  11. Beyond Feminism and the Dynamics of Mass Movements.

    Science.gov (United States)

    Gonzales, Sylvia

    In response to an article appearing in "The New York Times Magazine" by Anne Roiphe titled "The Trouble at Sarah Lawrence", which alleges "that the open visibility of female homosexuals in the student body, nourished by Sarah Lawrence's Women Studies Program, has led the prestigious college to ruin", this paper questions whether women's studies or…

  12. On-line measurement of food viscosity during flow

    DEFF Research Database (Denmark)

    Mason, Sarah Louise; Friis, Alan

    2006-01-01

    Sarah L. Mason and Alan Friis discuss some of the principles and equipment used to monitor food viscosity in real time.......Sarah L. Mason and Alan Friis discuss some of the principles and equipment used to monitor food viscosity in real time....

  13. A Case Study of a Parent's Educational Practice.

    Science.gov (United States)

    Coldron, John; Boulton, Pam

    1999-01-01

    Examines a parent's ("Sarah") educational practice and provides a description of her family. Focuses on how Sarah began her educational practice before her children were born, her conception of education and educational success, how she makes decisions in a context of uncertainty, and the role of emotions in her educational practice. (CMK)

  14. Breast cancer in female radium dial workers first employed before 1930

    International Nuclear Information System (INIS)

    Adams, E.E.; Brues, A.M.

    1980-01-01

    Female radium dial workers first employed before 1930 were analyzed for breast cancer mortality and incidence using method and rate tables described by Monson and the Mantel-Haenszel summary chi-square test for significance. Of 1180 located women, 736 were measured to estimate radium intake. This measured group was analyzed for breast cancer mortality and incidence according to four possible risk factors: radium intake dose, duration of employment, age at first exposure, and parity. The measured women showed a significant excess of breast cancer incidence and mortality only among those women with a radium intake of 50 μCi or greater

  15. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... tells a person how much to eat from different food groups based on age, gender, and activity level. Reviewed by: Sarah R. Gibson, ... of Nondiscrimination Visit the Nemours Web site. ...

  16. Pärt, Arvo: "Miserere", "Festina lente" / Volkmar Fischer

    Index Scriptorium Estoniae

    Fischer, Volkmar

    1991-01-01

    Uuest heliplaadist Pärt, Arvo: "Miserere", "Festina lente", "Sarah Was Ninety Years Old". The Hilliard Ensemble. Orchester der Beethovenhalle Bonn. Dirigent Dennis Russel Davies (ECM Records, distr Amigo)

  17. Bookeri lühinimekiri on valitud

    Index Scriptorium Estoniae

    2004-01-01

    Briti prestiizhseima kirjandusauhinna "The Man Booker Prize" lühinimekirja on jõudnud järgmised autorid: Achmat Dangor, Sarah Hall, Alan Hollinghurst, David Mitchell, Colm T̤ibín, Gerard Woodward jt.

  18. Groundbreaking approach to disaster relief

    OpenAIRE

    2008-01-01

    The humanitarian response to Cyclone Nargis, which struck Myanmar on 2 and 3 May, heralds a fundamentally new approach to relief coordination. As a result, a unique survey showed what really happened to the survivors. Sarah Cumberland reports.

  19. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... a spinal cord injury important? play_arrow What role does “compression” play in a spinal cord injury? ...

  20. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... do to prevent pressure sores? play_arrow What role does diet and hydration play in preventing pressure ...

  1. Sexospécificités | Page 196 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    -urban South Asia and find fair and sustainable solutions. ... Yoseth Ariza Araύjo, Sarah Olson, and Coll Hutchison, winners of the Student Poster Awards, and Dr Susilowati Tana, Ecohealth Research Presentation Award winner, were all ...

  2. Near-peer mentorship for undergraduate training in Ugandan ...

    African Journals Online (AJOL)

    Near-peer mentorship for undergraduate training in Ugandan medical schools: views of undergraduate students. Godfrey Zari Rukundo, Aluonzi Burani, Jannat Kasozi, Claude Kirimuhuzya, Charles Odongo, Catherine Mwesigwa, Wycliff Byona, Sarah Kiguli ...

  3. Plaadid / Immo Mihkelson

    Index Scriptorium Estoniae

    Mihkelson, Immo, 1959-

    2002-01-01

    Heliplaatide Orlando poleo "La Buenode la Vida", Spider-Man "Music from and inspired by", James Last "Gentleman of Music", Morcheeba "Charango", The Vines "Highly Evolved", Jesus and Teh Mary Chain "21 Singles", Sarah Brightman "Encore", Wyclef Jean "Masquerade" arvustus

  4. Ideaalse ja vulgaarse maailma kokkupõrge / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2005-01-01

    Briti kaasaegse kunsti valiknäitus "Supernoova" Tallinna Kunstihoones. Kuraator on Caroline Douglas. Osalevad Jane ja Louise Wilson, Haluk Akakce, Richard Wright, Toby Ziegler, Sarah Morris, Keith Coventry

  5. 'Of peasants, peacocks and priests; a Portuguese village'

    OpenAIRE

    Iturra, Raul

    2009-01-01

    Made on very early equipment, silent 8mm film and tape recorder. Narration by Sarah Harrison. An early product of the Rivers Video Project. A film about a north Portuguese village in 1985, based on the fieldwork of Raul Iturra

  6. Selgusid aasta 2010 tegijad / Meelis Kaubi

    Index Scriptorium Estoniae

    Kaubi, Meelis

    2010-01-01

    Saare maakonna aasta õppijaks valiti Rehe Pagar OÜ juhataja Glaudja Majorova, Aasta koolitajaks Signe Sarah Arro, Aasta koolitussõbralikumaks organisatsiooniks Trelleborg IP Estonia ja Aasta koolitussõbralikumaks omavalitsuseks Pöide vald

  7. Interview of David Elliston Allen

    OpenAIRE

    Allen, David

    2009-01-01

    Interviewed on 12 April 1983 by Jack Goody and Alan Macfarlane and filmed and edited by Sarah Harrison. Made on old and low quality equipment. An interview of the historian and naturalist David Elliston Allen

  8. Secondhand Smoke: What It Means to You

    Science.gov (United States)

    ... Leads, Writers, and Editorial Assistance Sarah Gregory, Health Communications Specialist, CDC Peter Xiques, Writer, Science Applications International Corporation Vickie Reddick, Writer, Science Applications International Corporation Graphic Design C. Mark Van Hook, Graphic Designer, Science ...

  9. Clean Hands Count

    Medline Plus

    Full Text Available ... 36 Clinton roasts Trump at Al Smith charity dinner - Duration: 18:49. CBS News 586,360 views ... 5 HEALTHY HABITS Changed My Life | What I Eat In A Day - Duration: 17:04. Sarahs Day ...

  10. 1. IV avati Tallinna Kunstihoone galeriis šoti videokunstinäitus "Nähtamatud väljad"

    Index Scriptorium Estoniae

    2004-01-01

    Kuraatorid Sarah Felton ja Su Grierson, osalevad kunstnikud Victoria Clare Bernie, Samantha Clark, Maria Doyle, S. Felton, S. Grierson, Belinda Guidi, Anne Bjerge Hansen, Metacorpus, Jane McInally, Rosalind Nashashibi, Susannah Silver ja Susan Sloan

  11. Staarid, kellel on oma parfüüm

    Index Scriptorium Estoniae

    2006-01-01

    Parfüümidest: Britney Spearsi "Fantasy, Paris Hiltoni "Just Me", Maria Sharapova "Maria Sharapova", Sarah Jessica Parkeri "Lovely", Jennifer Lopezi "Still", David ja Viktoria Beckhami "Intimately Beckham"

  12. Keep Contacts Clean (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Contact lenses can be a comfortable and convenient alternative to traditional eye glasses, but without proper care, they can cause severe eye problems. In this podcast, Sarah Collier discusses the importance of proper maintenance of contact lenses.

  13. Brief Introduction to Hepatitis B for Parents of Adopted Children

    Science.gov (United States)

    Brief Introduction to Hepatitis B for Parents of Adopted Children by Sarah Jane Schwarzenberg, MD What is hepatitis B? ... injury will also need careful medical management. In short, prospective par- ents of children with hepatitis B ...

  14. Hollandi tudengineiu leidis Kullamaalt oma baltisaksa juured / Lehte Ilves

    Index Scriptorium Estoniae

    Ilves, Lehte, 1951-

    2009-01-01

    Hollandis Haarlemi ülikoolis teletööd õppiv Sarah Alberti koolitööks tehtav dokumentaalfilm oma juurtest, tõi neiu Kullamaale, kust ta leidis materjali oma baltisakslasest vanaema von Maydelli kohta

  15. Obstetric fistula: a narrative review of the literature on preventive ...

    African Journals Online (AJOL)

    Obstetric fistula: a narrative review of the literature on preventive ... Eniya K. Lufumpa, Sarah Steele ... The literature also highlights the need for increased governmental support, as a means of preventing the development of fistulas.

  16. 78 FR 37537 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

    Science.gov (United States)

    2013-06-21

    ... objectives (e.g., forward period, commitment period, product definition and specificity, market [email protected] . Sarah McKinley (Logistical Information), Office of External Affairs, Federal Energy...

  17. Work, health and wellbeing: the challenges of managing health at work

    National Research Council Canada - National Science Library

    Vickerstaff, Sarah; Phillipson, Chris; Wilkie, Ross

    2012-01-01

    ... has been requested. ISBN 978 1 84742 808 0 hardback The rights of Sarah Vickerstaff, Chris Phillipson and Ross Wilkie to be identified as editors of this work has been asserted by them in accordance wit...

  18. ASA24-Australia

    Science.gov (United States)

    The Australian project, led by Associate Professor Sarah McNaughton of The Institute for Nutrition and Physical Activity (IPAN) at Deakin University, brought together 5 national institutions with major research programs in nutrition.

  19. Chelsea Flower Show 2007 / Merilen Mentaal

    Index Scriptorium Estoniae

    Mentaal, Merilen, 1972-

    2007-01-01

    Uusimaid aiatrende Londonist. Enimkasutatud materjalid puit, eri vormi ja struktuuriga kivid ning vesi. Võiduaiaks kivifirma Bradstone'i aed "600 päeva Bradstone'iga", disainer Sarah Eberle. 15 värv. ill

  20. Bridging the divide

    Science.gov (United States)

    Tesh, Sarah

    2017-09-01

    The recent International Conference on Women in Physics shows that there is still a long way to go to reach gender equality. Sarah Tesh reports from Birmingham, UK - where education activist Malala Yousafzai made a surprise appearance

  1. How to Run Successful Teen Volunteer Programs - Forms for teen volunteers and teen advisory groups (TAG) -Powerpoint Presentations

    OpenAIRE

    Donald, Sarah; Donoghue, Vicki; Dawley, Amy

    2010-01-01

    Based on work with teen volunteers, teen advisory councils, teen reading buddy programs and anime and manga clubs, Sarah Donald, Vicki Donoghue and Amy Dawley discuss their successes with teenagers, and practical ways to serve teens in the community.

  2. 76 FR 47537 - Southern Arizona Resource Advisory Committee

    Science.gov (United States)

    2011-08-05

    ...: The meeting will be held at the Tucson Interagency Fire Center, 2646 E. Commerce Center Place, Tucson... be sent to Sarah Davis, Coronado National Forest, 300 W. Congress Street, Tucson, AZ 85701, or by e...

  3. Book Review: Greenwood, M. et al. (Eds.. (2015. Determinants of Indigenous Peoples' Health in Canada: Beyond the Social

    Directory of Open Access Journals (Sweden)

    Javier Mignone

    2017-03-01

    Full Text Available This article provides a review of the book Determinants of Indigenous Peoples’ Health in Canada: Beyond the Social edited by Margo Greenwood, Sarah de Leeuw, Nicole Marie Lindsay, and Charlotte Reading.

  4. Digging the METEOSAT Treasure—3 Decades of Solar Surface Radiation

    Directory of Open Access Journals (Sweden)

    Richard Müller

    2015-06-01

    Full Text Available Solar surface radiation data of high quality is essential for the appropriate monitoring and analysis of the Earth's radiation budget and the climate system. Further, they are crucial for the efficient planning and operation of solar energy systems. However, well maintained surface measurements are rare in many regions of the world and over the oceans. There, satellite derived information is the exclusive observational source. This emphasizes the important role of satellite based surface radiation data. Within this scope, the new satellite based CM-SAF SARAH (Solar surfAce RAdiation Heliosat data record is discussed as well as the retrieval method used. The SARAH data are retrieved with the sophisticated SPECMAGIC method, which is based on radiative transfer modeling. The resulting climate data of solar surface irradiance, direct irradiance (horizontal and direct normal and clear sky irradiance are covering 3 decades. The SARAH data set is validated with surface measurements of the Baseline Surface Radiation Network (BSRN and of the Global Energy and Balance Archive (GEBA. Comparison with BSRN data is performed in order to estimate the accuracy and precision of the monthly and daily means of solar surface irradiance. The SARAH solar surface irradiance shows a bias of 1.3 \\(W/m^2\\ and a mean absolute bias (MAB of 5.5 \\(W/m^2\\ for monthly means. For direct irradiance the bias and MAB is 1 \\(W/m^2\\ and 8.2 \\(W/m^2\\ respectively. Thus, the uncertainty of the SARAH data is in the range of the uncertainty of ground based measurements. In order to evaluate the uncertainty of SARAH based trend analysis the time series of SARAH monthly means are compared to GEBA. It has been found that SARAH enables the analysis of trends with an uncertainty of 1 \\(W/m^2/dec\\; a remarkable good result for a satellite based climate data record. SARAH has been also compared to its legacy version, the satellite based CM-SAF MVIRI climate data record. Overall

  5. Women in History--Madame C. J. Walker 1867-1919

    Science.gov (United States)

    Huber, Germaine W.

    2009-01-01

    This article profiles Madame C. J. Walker. Sarah Breedlove was born on December 23, 1867, the fifth of six children of Owen and Minerva Breedlove. Sarah was the first of the Breedlove children to be born after the end of slavery. Her parents died when she was six or seven years of age. At age fourteen she married Moses McWilliams, who also died in…

  6. The Future of the Ballistic Missile Submarine Force in the Russian Nuclear Triad

    Science.gov (United States)

    2008-09-01

    based forces are the more economical leg of the triad.61 An estimate made in 1995 by B.I. Pustovit , then the expert for the Committee for Military...Theodore Gerber, a professor of sociology at the University of Wisconsin–Madison, and Sarah Mendelson, a senior fellow in the Russia and Eurasia... Sarah Mendelson, “Strong Public Support for Military Reform in Russia” Program on New Approaches to Russian Security, Policy memo 288 (2003), 3. 45 In

  7. Cryomilling of Thermoplastic Powder for Prepreg Applications

    Science.gov (United States)

    2013-09-01

    Cryomilling of Thermoplastic Powder for Prepreg Applications by Brian Parquette, Anit Giri, Daniel J. O’Brien, Sarah Brennan, Kyu Cho, and...MD 21005-5066 ARL-TR-6591 September 2013 Cryomilling of Thermoplastic Powder for Prepreg Applications Brian Parquette and Sarah Brennan...COVERED (From - To) 1 March 2012–30 May 2013 4. TITLE AND SUBTITLE Cryomilling of Thermoplastic Powder for Prepreg Applications 5a. CONTRACT

  8. Bringing Bike Share to a Low-Income Community

    Centers for Disease Control (CDC) Podcasts

    2013-08-14

    This podcast is an interview with Sarah Kretman Stewart, MPH, MEd, Healthy Living Minneapolis Project Specialist at the Minneapolis Health Department. In this program, Sarah talks about the impact a bike share program had on the low-income town of Near North, Minnesota.  Created: 8/14/2013 by Preventing Chronic Disease (PCD), National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/14/2013.

  9. Effects of cognitive-behavioral conjoint therapy for PTSD on partners' psychological functioning.

    Science.gov (United States)

    Shnaider, Philippe; Pukay-Martin, Nicole D; Fredman, Steffany J; Macdonald, Alexandra; Monson, Candice M

    2014-04-01

    A number of studies have documented that posttraumatic stress disorder (PTSD) symptoms in "one" partner are negatively associated with their intimate partner's psychological functioning. The present study investigated intimate partners' mental health outcomes (i.e., depression, anxiety, and anger) in a sample of 40 partners of individuals with PTSD within a randomized waitlist controlled trial of cognitive-behavioral conjoint therapy for PTSD (Monson & Fredman, 2012). There were no significant differences between active treatment and waitlist in intimate partners' psychological functioning at posttreatment. Subgroup analyses, however, of partners exhibiting clinical levels of distress at pretreatment on several measures showed reliable and clinically significant improvements in their psychological functioning at posttreatment and no evidence of worsening. Results suggest that cognitive-behavioral conjoint therapy for PTSD may have additional benefits for partners presenting with psychological distress. Copyright © 2014 International Society for Traumatic Stress Studies.

  10. Dynamics of capillary condensation in lattice gas models of confined fluids: a comparison of dynamic mean field theory with dynamic Monte Carlo simulations.

    Science.gov (United States)

    Edison, John R; Monson, Peter A

    2013-06-21

    This article addresses the accuracy of a dynamic mean field theory (DMFT) for fluids in porous materials [P. A. Monson, J. Chem. Phys. 128, 084701 (2008)]. The theory is used to study the relaxation processes of fluids in pores driven by step changes made to a bulk reservoir in contact with the pore. We compare the results of the DMFT to those obtained by averaging over large numbers of dynamic Monte Carlo (DMC) simulation trajectories. The problem chosen for comparison is capillary condensation in slit pores, driven by step changes in the chemical potential in the bulk reservoir and involving a nucleation process via the formation of a liquid bridge. The principal difference between the DMFT results and DMC is the replacement of a distribution of nucleation times and location along the pore for the formation of liquid bridges by a single time and location. DMFT is seen to yield an otherwise qualitatively accurate description of the dynamic behavior.

  11. Dzhässikavad toovad linna jõulurõõmu / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2008-01-01

    "Jazzkaare" kolm dzhässiõhtut Pärnus - 3. dets. Eliisabeti kirikus Raivo Tafenau, Ain Agan ja Laura Põldvere, 9. dets. Endla teatris Saksamaa vokaalansambel Berlin Voices (Esther Kaiser, Sarah Kaiser, Marc Secara, Kristofer Benn) ja 11. dets. Ammende villas norra laulja Gine Andressen. Berlin Voices soojendusansamblina esineb Pärnu noorte vokaalansambel Greip

  12. Having Healthy Babies (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Most babies in the United States are born perfectly healthy. However, a small percentage are born with birth defects, and these conditions account for one of every five infant deaths in the United States. In this podcast, Dr. Sarah Tinker discusses ways for women to improve their chances of having a healthy baby.

  13. Becoming a Japanese Language Learner, User, and Teacher: Revelations From Life History Research

    Science.gov (United States)

    Armour, William S.

    2004-01-01

    This article discusses how Sarah Lamond, a Japanese language teacher in Sydney, Australia has juggled three of her identities: second language (L2) learner, L2 user, and L2 teacher. Data come from four interviews used to create an edited life history. These data are used to draw attention to the relationship between L2 learner and language user.…

  14. Browse Title Index

    African Journals Online (AJOL)

    Items 151 - 200 of 533 ... Vol 34, No 1 (2016), Determining ESL learners' vocabulary needs from a textbook corpus: challenges and prospects, Abstract. Jabulani Sibanda, Jean Baxen. Vol 20, No 4 (2002):, Determining the appropriate code in a South African business environment, Abstract. Marné Pienaar, Sarah Slabbert.

  15. Tähesadu kunstihoones

    Index Scriptorium Estoniae

    2005-01-01

    Tallinna Kunstihoones Briti Nõukogu koostatud näitus "Supernoova". Kuraator Caroline Douglas. Osalevad Gary Hume, Liam Gillick, Jane & Louise Wilson, Sarah Morris, Haluk Akakce, Phillip Allen, Keith Coventry, Dan Norton, Toby Paterson, Tony Swain, John Wood & Paul Harrison, Richard Wright, Toby Ziegler

  16. Wild Birds and the Urban Ecology of Ticks

    Centers for Disease Control (CDC) Podcasts

    2012-12-21

    Dr. Sarah Hamer, Assistant Professor and Veterinary Ecologist with the College of Veterinary Medicine at Texas A&M University, discusses her investigation of ticks on wild birds in urban Chicago.  Created: 12/21/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 12/27/2012.

  17. A review of birds in Uganda: records updating the Uganda Atlas and ...

    African Journals Online (AJOL)

    Wattled Crane Bugeranus carunculatus. On 2 May 2009 one was located at Kibimba Rice Scheme by Sarah Nachuha Kasozi .... the birds as Golden-naped Weavers. This record was published in the Bulletin of the ... on 2 April 1948. There were no other records until a bird was seen at Kibimba rice scheme on 20 November ...

  18. The Practices of Geography

    Science.gov (United States)

    Bednarz, Sarah Witham

    2016-01-01

    Sarah Bednarz begins by thanking Rebecca Theobald for the invitation to contrubute to this issue of "The Geography Teacher"("TGT"). As a member of the National Council for Geographic Education (NCGE) Publications Committee and coeditor of the "Journal of Geography," Bednarz confesses that she was not favorably…

  19. PÖFF käib vaikselt edasi / Margit Adorf

    Index Scriptorium Estoniae

    Adorf, Margit, 1974-

    2007-01-01

    PÖFFi filme: Wong Kar-Wai mängufilm "Mu mustikakarva ööd" ("My Blueberry Nights") : Hongkong - Hiina - Prantsusmaa 2007 ja loodusfilm "Arktika lugu" ("Arctic Tale") : režissöörid Sarah Robertson, Adam Ravetch : Ameerika Ühendriigid 2007

  20. The Social Relevance of Montessori in the First Plane

    Science.gov (United States)

    Andrews, Sarah Werner

    2015-01-01

    This article represents an amazing reversal of linguistic analysis. Usually Montessori language is translated into "state" terminology. In this case, Sarah Werner Andrews puts state quality assessment terms into Montessori language. For example, domains for school readiness include 1) physical wellbeing and motor development, 2) social…

  1. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. Gh Jeelani. Articles written in Journal of Earth System Science. Volume 120 Issue 3 June 2011 pp 399-411. Assessing variability of water quality in a groundwater-fed perennial lake of Kashmir Himalayas using linear geostatics · S Sarah Gh Jeelani Shakeel Ahmed.

  2. 75 FR 68636 - President's Working Group Report on Money Market Fund Reform

    Science.gov (United States)

    2010-11-08

    ... Sarah ten Siethoff at (202) 551-6792, Division of Investment Management, Securities and Exchange... question of whether further, more fundamental changes to the regulatory structure governing money market funds may be warranted.\\5\\ \\3\\ Money Market Fund Reform, Investment Company Act Release No. 29132 (Feb...

  3. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... is that eating to reach your peak performance level likely doesn't require a special diet or supplements. It's all about working ... the U.S. government's website ChooseMyPlate.gov , which tells a person how much to eat ... level. Reviewed by: Sarah R. Gibson, MD Date reviewed: ...

  4. Novel Eurasian Highly Pathogenic Influenza A H5 Viruses in Wild Birds, Washington, USA, 2014

    Centers for Disease Control (CDC) Podcasts

    2015-03-24

    Sarah Gregory reads an abridged version of the article, Novel Eurasian Highly Pathogenic Influenza A H5 Viruses in Wild Birds, Washington, USA, 2014.  Created: 3/24/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 4/13/2015.

  5. Action needed to help Cape Town adapt to climate change | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-06-09

    Jun 9, 2016 ... The impacts of climate change on the city of Cape Town, South Africa, are outlined in a new book, Climate Change at the City Scale. IDRC-supported researchers Anton Cartwright, Susan Parnell, Gregg Oelofse, and Sarah Ward argue that local governments and scientists need to work together to take ...

  6. Short Note A perceived local extinction of Red-billed Oxpeckers in ...

    African Journals Online (AJOL)

    Short Note A perceived local extinction of Red-billed Oxpeckers in the Yabelo region, southern Ethiopia. Richard J Mellanby, Celia Broadhurst, Mengistu Wondafrash, Mihiret Ewnetu, Sandy Watt, Rob Critchlow, Aman Dadesa, Tom Deas, Chere Enawgaw, Berihun Gebremedhin, Ellie Graham, Sarah MacLean, Ben Ross ...

  7. The Darjeeling Distinction: Labor and Justice on Fair-Trade Tea Plantations in India

    Directory of Open Access Journals (Sweden)

    Julia Poerting

    2015-05-01

    Full Text Available Reviewed: The Darjeeling Distinction: Labor and Justice on Fair-Trade Tea Plantations in India. By Sarah Besky. Berkeley, CA: University of California press, 2014. xxxi + 233 pp. US$ 29.95. ISBN 978-0-520-27739-7.

  8. bouwen aan morgen met het bouwmateriaal van gisteren: tobit 7-8 ...

    African Journals Online (AJOL)

    He realises that it will only be possible to share a future together if the chaos of Sarah's past can be transformed, which begins when Tobias kills the voracious fish in the Tigris. River, a symbolic representation of destructive chaos. Once this has been defeated, Tobias is also able to triumph over Asmodeus, the demon ...

  9. Bouwen aan morgen met het bouwmateriaal van gisteren: Tobit 7-8 ...

    African Journals Online (AJOL)

    He realises that it will only be possible to share a future together if the chaos of Sarah's past can be transformed, which begins when Tobias kills the voracious fish in the Tigris River, a symbolic representation of destructive chaos. Once this has been defeated, Tobias is also able to triumph over Asmodeus, the demon ...

  10. Antinociceptive Properties and Acute Toxicity of Ethanol Extract of ...

    African Journals Online (AJOL)

    Sarah RG de Lima-Saraiva1, Henrique CC Saraiva2, Juliane C Silva2, Leonardo ... 56.304-205, Petrolina, Pernambuco, 3Universidade Estadual de Feira de ..... Santos VNC, Freitas RA, Deschamps FC, Biavatti, MW. ... Queiroz AC, Lira DP, Dias TL, Souza ET, Matta CB, ... Alexandre-Moreira MS, Piuvezam MR, Araújo CC,.

  11. Download this PDF file

    African Journals Online (AJOL)

    Owner

    There have been several other translations of Marais's work as well, from Sarah. Goldblatt herself with ..... Marais, understandably he skirted details of this demolition job, and continued to do ... disdaining to use my thunder” (592–93). With all ...

  12. Determining Permissible Oxygen and Water Vapor Transmission Rate for Non-Retort Military Ration Packaging

    Science.gov (United States)

    2011-11-01

    OXYGEN AND WATER VAPOR TRANSMISSION RATE FOR NON- RETORT MILITARY RATION PACKAGING by Danielle Froio Alan Wright Nicole Favreau and Sarah...ANSI Std. Z39.18 RETORT STORAGE SHELF LIFE RETORT POUCHES SENSORY ANALYSIS OXYGEN CRACKERS PACKAGING SENSORY... Packaging for MRE. (a) MRE Retort Pouch Quad-Laminate Structure; (b) MRE Non- retort Pouch Tri-Laminate Structure

  13. The Right to Dissent and Its Implications for Schooling

    Science.gov (United States)

    Stitzlein, Sarah M.

    2012-01-01

    In this article Sarah Stitzlein highlights an educational right that has been largely unacknowledged in the past but has recently gained significance given renewed citizen participation in displays of public outcry on our streets and in our town halls. Dissent is typically conceived of as a negative right--a liberty that guarantees that the…

  14. Similarities and Differences in Patterns and Geolocation of SSH Attack Data

    Science.gov (United States)

    2015-09-01

    mysql , oracle, sarah, and louise were then configured on the honeypots, admin as the root user and the other four as non-privileged user accounts [10...The data did, however, disclose the most popular course of action, which “was to check the software configuration, change the password, check the

  15. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... eat from different food groups based on age, gender, and activity level. Reviewed by: Sarah R. Gibson, MD Date reviewed: September 2014 More on this topic for: Teens Nutrition & Fitness Center Sports Physicals Figuring Out Fat and Calories Sports Center ...

  16. 78 FR 21934 - Coordination Between Natural Gas and Electricity Markets; Supplemental Notice of Technical...

    Science.gov (United States)

    2013-04-12

    ...) 502-6682, [email protected] . Sarah McKinley (Logistical Information), Office of External... the benefits and costs to each approach? Given technological advances, are there opportunities to reduce the time between electric offers and resource commitment? What would the benefits and costs be to...

  17. How to appoint a new chief nurse, win friends and influence people.

    Science.gov (United States)

    Butterworth, Tony

    2004-07-01

    OUR CHIEF nurse for England, Sarah Mullally, has announced her intention to leave the NHS and the search is on for her replacement. Speculation on who it will be is rife; this is an opportune moment therefore to reflect on the ideal qualities of the new chief nursing officer (CNO) for England.

  18. Maydellide järeltulija teeb filmi oma juurtest / Maire Kõrver

    Index Scriptorium Estoniae

    Kõrver, Maire, 1961-

    2009-01-01

    Eestis, sh Raplamaal viibis Hollandis Haarlemi ülikoolis teletööd õppiv Maydellide järeltulija Sarah Albert, kes teeb koolitööna dokumentaalfilmi oma juurtest. Külaskäigust vanas mõisahoones asuvasse Maidla lastekodusse, Teenuse mõisa, Kullamaa kirikusse ja kalmistule ning Päri mõisa

  19. Human Robotic Swarm Interaction Using an Artificial Physics Approach

    Science.gov (United States)

    2014-12-01

    Sarah has done an amazing job at being a mom and a spouse to a sometimes eccentric naval officer. Most importantly, I’d like to thank Jesus Christ...physicometics-based frame- work in a four-robot auditory scene monitoring scenario [19]. In his experiments, Apker et al. uses the four- wheeled Pioneer3-AT ground

  20. 76 FR 7907 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2011-02-11

    ... PATRICK COYLE BRENDAN H D'ALVIELLA EUGENIE AIMEE GOBLET DARWIN ANGELA MARY BRUCE DAVID CARY RICHARD DAVID... ELIZABETH U FUNG PASCALE N GIBSON MATTHEW CHARLES GIBSON SARAH CLAIRE GIDRON GILLA MEZZAN GINDIN DMITRY... LINDA ANETTE HANSEN PAUL ROBERT HARDWICK III CHARLES CHEEVER HARRIS JANE VELDA HARSONO SUDARGO HARTLEY...

  1. Teaching in the Restorative Window: Authenticity, Conviction, and Critical-Restorative Pedagogy in the Work of One Teacher-Leader

    Science.gov (United States)

    Fine, Sarah M.

    2018-01-01

    In this article, Sarah M. Fine uses portraiture to explore the undertheorized question of what it means to teach in ways that align with the values of the restorative justice framework. The piece centers around the work of Nora, a veteran teacher-leader who explored this question in the context of her own classroom and, as a result, shifted her…

  2. Sead, joodikud ja muidu tõprad rohelisel ekraanil / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2004-01-01

    Iiri filmiprogrammis "Green Screen", mille on koostanud Iiri Filmiinstituut ja Iiri Filminõukogu Euroopa Liitu astuvate riikide jaoks, võib kinos "Sõprus" näha kaheksat uuemat filmi. Tutvustavalt kahest mängufilmist : Kirsten Sheridani "Diskopõrsad" ja Aisling Walshi "St Jude'i vangid" ning Sarah Share'i portreefilmist "Shane MacGowani lugu"

  3. 26. IX sai Kumus kokku Euroopa Nõukogu juurde kuuluv Euroopa Näituse nõukogu / Sirje Helme ; interv. R[eet] V[arblane

    Index Scriptorium Estoniae

    Helme, Sirje, 1949-

    2007-01-01

    Kumus toimunud Euroopa Näituse seminarist, mille eesmärgiks oli näituse "Kunst pärast aastat 1945" kontseptsiooni, sisu jm. väljatöötamine. Seminaril osalesid Piotr Piotrowski, Lazlo Beke, Monika Flacke, Sarah Wilson, Anda Rottenberg, Viktor Misiano jt. Seminari Kumus korraldamise põhjustest, mida seminari Eestis läbiviimine meile annab

  4. For Your Bookshelf.

    Science.gov (United States)

    Jones, Rebecca

    2002-01-01

    Reviews notable education books of 2001: "Not in Front of the Children" (Marjorie Heins); "The other Boston Busing Story" (Susan E. Eaton); "Another Planet" (Elinor Burkett); "Parents Under Siege" (James Garbarino and Claire Bedard); "Radical Equations" (Robert P. Moses and Charles E. Cobb, Jr.); "School" (Sheila Curran Bernard and Sarah Mondale);…

  5. Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment | Poster

    Science.gov (United States)

    Noriho Iida, Amiran Dzutsev, C. Andrew Stewart, Loretta Smith, Nicolas Bouladoux, Rebecca A. Weingarten, Daniel A. Molina, Rosalba Salcedo, Timothy Back, Sarah Cramer, Ren-Ming Dai, Hiu Kiu, Marco Cardone, Shruti Naik, Anil K. Patri, Ena Wang, Francesco M. Marincola, Karen M. Frank, Yasmine Belkaid, Giorgio Trinchieri, Romina S. Goldszmid Science 342(6161):967-970, 2013

  6. Acceptability, feasibility and challenges of implementing an HIV ...

    African Journals Online (AJOL)

    Prafulta Jaiantilal

    2015-03-17

    Mar 17, 2015 ... Sarah A. Gutinb, Beverley Cummingsc, Francisco Mbofanad,. Carol Dawson Rosee .... 2006; World Health Organization. 2007). In the USA .... riers and facilitators to behavior change, risky or unsafe behaviors and attitudes toward ... ware Development 2011), a qualitative analysis software tool, was used to ...

  7. Nipah Virus Transmission from Bats to Humans Associated with Drinking Traditional Liquor Made from Date Palm Sap, Bangladesh, 2011–2014

    Centers for Disease Control (CDC) Podcasts

    2016-06-30

    Sarah Gregory reads an abridged version of the article, Nipah Virus Transmission from Bats to Humans Associated with Drinking Traditional Liquor Made from Date Palm Sap, Bangladesh, 2011–2014.  Created: 6/30/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 6/30/2016.

  8. Resurgence of Yellow Fever in Angola, 2015–2016

    Centers for Disease Control (CDC) Podcasts

    2016-10-12

    Sarah Gregory reads an abridged version of an article on the resurgence of yellow fever in Angola.  Created: 10/12/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 10/12/2016.

  9. Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014

    Centers for Disease Control (CDC) Podcasts

    2016-08-16

    Sarah Gregory reads an abridged version of the article, Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014.  Created: 8/16/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 8/16/2016.

  10. Pandemic Fear and Literature: Observations from Jack London’s The Scarlet Plague

    Centers for Disease Control (CDC) Podcasts

    2014-11-18

    Sarah Gregory reads an abridged version of the essay, Pandemic Fear and Literature: Observations from Jack London’s The Scarlet Plague.  Created: 11/18/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 11/20/2014.

  11. Keep Contacts Clean (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2014-11-20

    Contact lenses can be a comfortable and convenient alternative to traditional eye glasses, but without proper care, they can cause severe eye problems. In this podcast, Sarah Collier discusses the importance of proper maintenance of contact lenses.  Created: 11/20/2014 by MMWR.   Date Released: 11/20/2014.

  12. The Kinetics and Dynamics of Elementary Gas-Phase Reactions

    Science.gov (United States)

    2002-09-01

    Philip James Alam Hasson Sarah Wright Kevin Hickson Delphine Chastaing Peter Barnes Simon Beach Paul Barrass David Carty Alejandra Paramo ...Ghana micghosei@yahoo.com Professor Richard Palmer University of Birmingham, UK R.E.Palmer@bham.ac.uk Ms Alejandra Paramo University of

  13. Computer Modeling of the Effects of Atmospheric Conditions on Sound Signatures

    Science.gov (United States)

    2016-02-01

    simulation. 11 5. References 1. Attenborough K. Sound propagation in the atmosphere. In: Rossing TD, editor. Springer handbook of...ARL-TR-7602 ● FEB 2016 US Army Research Laboratory Computer Modeling of the Effects of Atmospheric Conditions on Sound ...Laboratory Computer Modeling of the Effects of Atmospheric Conditions on Sound Signatures by Sarah Wagner Science and Engineering Apprentice

  14. 1984 Program Report on the Army-Navy Initiative in the National Capital Area in Support of the Department of Defense Science and Engineering Apprenticeship Program for High School Students

    Science.gov (United States)

    1985-03-01

    Mexico . The other method was by the Faraday Rotation Principle calculated by polarimeter here at the lab. To measure the TEC by either method gives a base...shock in chronic rats. Springbrook High School Montgomery County, Md. Sarah Gaffen Investigated the herpes Varicella Mentor: Dr. John Hay Zoster virus

  15. 2015 Military Investigation and Justice Experience Survey (MIJES). Overview Report

    Science.gov (United States)

    2016-03-16

    consisting of Ms. Natalie Namrow, Ms. Sarah De Silva, Ms. Kathleen Dippold, SRA International, Inc., a CSRA Company, Dr. Samantha Daniel, Dr. Paul Cook ...construed as substantiated allegations of professional reprisal, ostracism, or maltreatment. General Satisfaction With Individuals/Resources... Professional Reprisal, Ostracism, and Maltreatment The Department strives to create an environment where military members feel comfortable and safe

  16. Fulltext PDF

    Indian Academy of Sciences (India)

    mounted on a slender intensely red stalk and arranged into long , drooping , candelabra-like sprays. Stamens are ten with long filaments. The young pods are brilliant crimson. The plant's name was given in honour of Sarah, Countess of Amherst, wife of the governor of Myanmar; nobilis, on account of the exquisite beauty of ...

  17. Chelsea - pelgupaik keset suurlinna / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1975-

    2007-01-01

    Chelsea Flower Show'st, millest jäid märksõnadena meelde looduslähedus, ühiskondlik hoolivus ja minevikuihalus. Parima näituseaia tiitli pälvis Sarah Eberle kujundatud kosmoseaed "600 Days with Bradstone". Pikemalt ka Andi Sturgeoni kujundatud vähiuuringute keskuse aiast. 10 värv. vaadet

  18. For Youth, by Youth: A Third Student-Run Homeless Shelter

    Science.gov (United States)

    Seider, Scott C.

    2016-01-01

    This past winter, the third student-run homeless shelter in the United States came into being. Two recent Harvard graduates, Sam Greenberg and Sarah Rosenkrantz, who had volunteered at the Harvard Square Homeless Shelter as college students, saw a need within the Boston and Cambridge communities for a homeless shelter serving young adults. Drawing…

  19. Think Aloud in Groups: Mediating Poetry for Children with Cecília Meireles, Paulo Freire, and John Dewey

    Science.gov (United States)

    Diniz, Telma Franco

    2018-01-01

    As suggested by its title, this article reports on a Think Aloud in Group (TAG) practice in which a group of Y5 children thought aloud the poem "The Blue Boy", written in Portuguese by Cecília Meireles and translated into English by Sarah Rebecca Kersley. As a dialogical and collaborative literacy practice, TAG aims to transform the…

  20. Invités de marque, conférenciers de renom et près de 4 000 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 juin 2016 ... Mettant en vedette Edward Cameron, directeur général, Business for Social Responsibility; Maria Emilia Correa, cofondatrice, Sistema B; Duncan Onyango, directeur, Afrique de l'Est, Acumen; et Sarah Keyes, directrice – durabilité, recherche, orientation et soutien, Comptables professionnels agréés ...

  1. A Novel Hand-Held Optical Imager with Real-Time Co-Registration Facilities Towards Diagnostic Mammography

    Science.gov (United States)

    2012-01-01

    patients after microdose administration of near-infrared f uorophore: A feasibility study,” Radiol- ogy, vol. 246, no. 3, pp. 734–741, 2008. Sarah J...Adams KE, et al. (2008). Imaging of lymph flow in breast cancer patients after microdose administration of a near-infrared fluorophore: feasibility

  2. Putative Lineage of Novel African Usutu Virus, Central Europe

    Centers for Disease Control (CDC) Podcasts

    2015-10-15

    Sarah Gregory reads an abridged version of "Putative Lineage of Novel African Usutu Virus, Central Europe.".  Created: 10/15/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 10/15/2015.

  3. Unfolding a Problem

    Science.gov (United States)

    Currier, Sarah Cox

    2015-01-01

    In this article, Sarah Currier, a math specialist at Elizabeth Hall International School in Minnesota, describes how she used origami in a deliberate manner to teach content. She shares how she uses paper folding to teach mathematical concepts, reinforce vocabulary, and as a problem-solving model. She also offers ideas for using origami in other…

  4. Correction Notice: Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom

    Directory of Open Access Journals (Sweden)

    JMBE Production Editor

    2016-05-01

    Full Text Available Correction for Sarah E. Council and Julie E. Horvath, “Tools for Citizen-Science Recruitment and Student Engagement in Your Research and in Your Classroom,” which appeared in the Journal of Microbiology & Biology Education, volume 17, number 1, March 2016, pages 38–40.

  5. Formation of atoll garnets in the UHP eclogites of the Tso Morari ...

    Indian Academy of Sciences (India)

    Mallika K Jonnalagadda

    2017-11-22

    Nov 22, 2017 ... Shivani Harshe1, Sarah Gain2 and William L Griffin2. 1. Department of ..... M orari complex. L1. -. N ormal. G arnet. T rav erse. Mineral. G arnet. A mp. Garnet. Cp x. G ...... along with white mica occur as shear bands (0.5. GPa and 500 ..... erals in the crust; Treatise on Geochemistry, Amsterdam. Elsevier 3 ...

  6. Mobile health for early retention in HIV care: a qualitative study in ...

    African Journals Online (AJOL)

    Mobile health for early retention in HIV care: a qualitative study in Kenya (WelTel Retain). Kirsten Smillie, Natasha Van Borek, Mia L van der Kop, Abigael Lukhwaro, Neville Li, Sarah Karanja, Anik R Patel, David Ojakaa, Richard T Lester ...

  7. 2017 summer reading from IDRC.ca | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-08-15

    Aug 15, 2017 ... Farmers like Sarah and Christopher Senyumba-Zake can now raise livestock in Kampala, Uganda. From the ground up: Urban agriculture reforms take root. Dr Noah Adamtey speaking to small-holder farmers in Kenya about composting techniques. From waste to fertilizer: IDRC awardee closing the ...

  8. Browse Author Index

    African Journals Online (AJOL)

    Skinner, Donald · Skinner, Donald · Skovdal, Morten · Sliep, Yvonne · Smillie, Kirsten · Smit, Jennifer A. Smith, Dawn K · Smith, Helen · Smith, Julia · Smith, Sarah · Snipstad, Mai Bente · Sodemann, Morten · Soko, Mavis · Sone, Albert Mouelle · Souza, Emmanuel · Spark-du Preez1, N · Spiegel, Paul B · Sprague, Courtenay

  9. Resisting Biopolitics through “Diaphanous Wonder”: Richard Flanagan's Gould's Book of Fish

    NARCIS (Netherlands)

    Wiese, Doro|info:eu-repo/dai/nl/304842699

    2014-01-01

    In Gould's Book of Fish (2003), author Richard Flanagan manages to invent a format in which content and style account for historical events on Sarah Island, Tasmania in the 1820s, yet he does so in a manner that is not in the least objective, disinterested or fact-orientated. The perspective of

  10. Assessing What Factors Are Driving the Army Civilian Acquisition Multigenerational Workforce Age/Experience Mix

    Science.gov (United States)

    2015-05-06

    45 viii ix Abstract Generation members are born , start school, enter the workforce, have children, and retire at about the...and Army acquisition workforce has evolved into a multigenerational workforce of young (Millennials, born 1980–2000), middle age (Generation X, 1965...younger workforce. Editors of TDn2K, a restaurant workforce data and analytics provider firm ( Restaurant Hospitality, 2014), quoting Sarah Atkinson

  11. Veterinary Research Manpower Development for Defense

    Science.gov (United States)

    2013-09-01

    Center Karen Alroy 2008 2012 Intern/Small Animal – Friendship Hospital for Animals Sarah Carter 2008 2010 Veterinarian - MSPCA at Nevins Farm ...Mukherjee, J.: Preliminary studies for the identification of brucella melitensis in the Dominican Republic goat population. 2011 Merial-NIH National

  12. 78 FR 49270 - Information Collection; MyUSA

    Science.gov (United States)

    2013-08-13

    ... personal and/or business confidential information provided. FOR FURTHER INFORMATION CONTACT: Sarah Crane... information collected is basic profile information, and may include: name, home address, phone number, gender... small business owner, a parent or a student. Use of the system, and contribution of personal information...

  13. Piiritagune teater huvitab igat näitlejat / Kadri Bank

    Index Scriptorium Estoniae

    Bank, Kadri

    2006-01-01

    VIIIndast rahvusvahelisest sõltumatute ja amatöörteatrite festivalist "Apostrof" Prahas 30. VII - 4. VIII, kus osales ka Tartu Üliõpilasteater lavastusega "Puhastatud" (autor Sarah Kane, lavastaja Kalev Kudu). Lavastus pälvis publikuhääletusel 14 osaleja seas viienda koha

  14. Discipline and Pleasure: The Pedagogical Work of Disneyland

    Science.gov (United States)

    Aronstein, Susan L.; Finke, Laurie A.

    2013-01-01

    Disneyland is work disguised as play; school disguised as vacation. While Walt Disney's curriculum deploys across all of its products, it literally engulfs the approximately 50 million "guests" who visit the Disney Parks each year. Drawing on Sarah Ahmed's phenomenological reading of orientation in Queer phenomenology, this…

  15. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... eat from different food groups based on age, gender, and activity level. Reviewed by: Sarah R. Gibson, MD Date reviewed: September 2014 More on this topic for: Teens Nutrition & Fitness Center Sports Physicals Figuring Out Fat and Calories Sports Center Vitamins ...

  16. New observations on the stratigraphy and radiocarbon dates at the Cross Creek site, Opito, Coromandel Peninsula

    International Nuclear Information System (INIS)

    Furey, L.; Petchey, F.; Sewell, B.; Green, R.

    2008-01-01

    This paper re-examines stratigraphy and radiocarbon dates at Cross Creek in Sarah's Gully. Three new radiocarbon dates are presented for Layer 9, the earliest, and previously undated, occupation. This investigation is part of a programme of archaeological work being carried out on the Coromandel Peninsula. (author). 51 refs., 4 figs., 3 tabs

  17. A Hermeneutic Phenomenological Approach to Understanding ...

    African Journals Online (AJOL)

    User

    focus in a new way, it enables us to glimpse the phenomenon anew, with the prospect of .... three girls (Claudia, Sarah and Kamille) and three ... were registered in the enriched school programme. .... phenomenological dynamic offers an original and ..... is a registered nurse and Professor in the Department of Education,.

  18. Why the Government Needs a Little History Lesson

    Science.gov (United States)

    Benn, Melissa

    2014-01-01

    The decision by ex-Secretary of State for Education Michael Gove to send his daughter to a state school caused much press comment and was discussed in a widely read article by Gove's spouse, the "Daily Mail" columnist Sarah Vine. In this piece, Vine praised non selective state education, drawing on her own personal experience and that of…

  19. Teen Scene Vaccines (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Vaccination of infants and toddlers is a common and well-accepted practice in the U.S. However, parents need to be aware of shots that are recommended for preteens. In this podcast, Dr. Sarah Reagan-Steiner discusses the importance of ensuring that older children are up-to-date on their vaccines.

  20. 75 FR 11149 - Bowersock Mills and Power Company; Notice of Application Tendered for Filing With the Commission...

    Science.gov (United States)

    2010-03-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13526-001] Bowersock Mills...: Bowersock Mills Power Company (Bowersock). e. Name of Project: Bowersock Mills and Power Company Expanded....S.C. 791(a)-825(r). h. Applicant Contact: Sarah Hill-Nelson, The Bowersock Mills and Power Company...

  1. Researching and Theorizing the "Age Taboo" on Intergenerational Sexualities

    Science.gov (United States)

    Yuill, Richard; Elliot, David

    2012-01-01

    By means of an ethnographic project, Sarah Goode's Understanding and Addressing Adult Sexual Attraction to Children aspires to better understand the self-conception and self-identification of pedophiles, with the ultimate aim of deconstructing the phenomenon by which culture demonizes pedophiles in order to better protect children. However, the…

  2. African Journal of AIDS Research - Vol 9, No 4 (2010)

    African Journals Online (AJOL)

    The effects of gender and socioeconomic status on youth sexual-risk norms: evidence from a poor urban community in South Africa · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Michael Rogan, Michaela Hynie, Marisa Casale, Stephanie Nixon, Sarah Flicker, Geoff Jobson, ...

  3. Contrapower Sexual Harassment of Military Officers

    Science.gov (United States)

    2007-08-01

    Sexual Harassment 1 Contrapower Sexual Harassment of Military Officers Sexual harassment is generally categorized in one of two ways: quid pro quo ...power or status over the victim (McKinney, 1992). The very definition of quid pro quo sexual harassment generally necessitates a superior harassing a...Contrapower Sexual Harassment of Military Officers A Thesis Presented by Sarah K. Clapp to the

  4. Learning Lichens

    Science.gov (United States)

    Thorne, Sarah

    2017-01-01

    The lichen is an ideal subject for student study because it is omnipresent in school yards, easily collected and observed year-round, a pioneer of evolution on land, and a bioindicator of air pollution. After doing fieldwork on this unusual composite organism as an apprentice with a team of lichenologists, Sarah Thorne developed Learning Lichens.…

  5. Appel à propositions pour le concours de 2018 du Programme ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 nov. 2017 ... Zipline uses drone technology to save lives. Sarah Farhat / Banque mondiale. Le CRDI, l'Israel Science Foundation, la Fondation Azrieli et les Instituts de recherche en santé du Canada annoncent l'appel de propositions pour la quatrième ronde du Programme conjoint canado-israélien de recherche en ...

  6. Assessment of Self-Efficacy in Systems Engineering as an Indicator of Competency Level Achievement

    Science.gov (United States)

    2014-06-01

    i.e., students, or entry level employees) towards a common goal (i.e., the desired future state) (Ponton et al. 2001, 247). Robbins , Bradley and...04, MIT Sloan, Cambridge, MA. Lucas, William A., Sarah Y. Cooper, Tony Ward, and Frank Cave. 2009. “Industry Placement, Authentic Experience and

  7. Working in the Finance and Procurement Department

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    The CERN Finance and Procurement (FP) Department handles around 35,000 internal purchase orders every year. A large number of them are processed by administrative assistant Sarah Pamelard and her two colleagues Dominique Trolliet and Laurence Fol. As you will see, this is not just any old desk job.   Sarah Pamelard in her office. Sarah Pamelard has worked at CERN for 23 years (see box). She began her career as an assistant in the electronics design office and has been an administrative assistant in the FP Department's purchasing service for the last year and a half. Her work involves processing all internal purchase orders for amounts not exceeding 10,000 CHF. "For each order we have to find the supplier who will provide the best services. Our search covers suppliers in all the Member States to ensure the best possible balance of financial return among them", explains Sarah. The skills that the job demands are not confined to the area of finance. Above all, you need to be very w...

  8. A Baseline Description of DTIC Scientific and Technical Information Support System

    Science.gov (United States)

    1986-09-01

    discussed below. Operations Research And Economic Analysis Office (DTIC-LO) This organizational element is currently being staffed. Its primary planned... Analysis Centers DASIAC - Ed Martin, Dave Reitz GACIAC - Richard Bartl* MCIAC - Helen Pestel * MMIAC - Sarah Ellingsworth...Overall Organization 2-5 Office Of The Administrator And Personal Staff 2-7 Equal Employment Opportunity Manager 2-7 Information Analysis

  9. First, Do No Harm: Teaching Writing in the Wake of Traumatic Events

    Science.gov (United States)

    DeBacher, Sarah; Harris-Moore, Deborah

    2016-01-01

    Sarah DeBacher and Deborah Harris-Moore offer their experiences with teaching in the aftermath of traumatic situations. DeBacher, who taught at the University of New Orleans in the aftermath of Hurricane Katrina, and Harris-Moore, who taught at UC Santa Barbara following a mass shooting, explore the difficulty of teaching writing in the wake of…

  10. Discerning the Chemical Composition and Mutagenic Effects of Soy Biodiesel PM

    Science.gov (United States)

    Discerning the Chemical Composition and Mutagenic Effects of Soy Biodiesel PM David G. Nashab, Esra Mutluc, William T. Prestond, Michael D. Haysb, Sarah H. Warrenc, Charly Kingc, William P. Linakb, M. lan Gilmourc, and David M. DeMarinic aOak Ridge Institute for Science and Ed...

  11. Joint Operating Environment: Trends and Challenges for the Future Joint Force Through 2030

    Science.gov (United States)

    2007-12-01

    and political discontent as demonstrated recently by powerful criminal organizations in Rio de Janeiro challenging government control and...infections in developing countries where 95 percent of urban sewage is dumped untreated in rivers and lakes. Water pollution is estimated to cause...5 De Benitez, Sarah Thomas et al. (2003) Youth Explosion in Developing World Cities: Approaches to reducing

  12. Bentley Research Fellowship

    International Development Research Centre (IDRC) Digital Library (Canada)

    2008-04-12

    Dr Bentley passed away April 12, 2008. The 2016 Bentley Research Fellowship was awarded to Sarah Allen, PhD candidate in Geography at York University. The Fellowship supported her research entitled: Urban Water Scarcity in the Mekong River Delta, Vietnam: An Urban Political Ecology Analysis of Urbanization and ...

  13. 78 FR 9660 - Pacific Halibut Fisheries; Catch Sharing Plan

    Science.gov (United States)

    2013-02-11

    ... accepted in Microsoft Word, Excel, or Adobe PDF file formats only. FOR FURTHER INFORMATION CONTACT: Sarah... the Sekiu River mouth, as defined by a line extending from 48[deg]17.30' N. lat., 124[deg]23.70' W... changes will have a disproportionate negative effect on small entities versus large entities. Based on the...

  14. Pariisis armastatakse kunsti / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2011-01-01

    Ameerika päritolu 20. sajandi alguse kunstimetseenide Leo, Gertrude, Michael ja Sarah Steini kunstikogule pühendatud Grand Palais' väljapanekust "Matisse, Cézanne, Picasso... Steinide perekond". Jeu de Paume'i ameerika fotokunstniku Diane Arbusi retrospektiivnäitusest

  15. Research Article ( New England Journal of Medicine ) A trial of a 7 ...

    African Journals Online (AJOL)

    Research Article (New England Journal of Medicine) A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults. Neil French, Stephen B. Gordon, Thandie Mwalukomo, Sarah A. White, Gershom Mwafulirwa, Herbert Longwe, Martin Mwaiponya, Eduard E. Zijlstra, Malcolm E. Molyneux, Charles F. Gilks ...

  16. Publications | Page 366 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 3651 - 3660 of 6384 ... Sarah McCans grew up in Montreal and earned an undergraduate degree in human geography at Queen's University in Kingston, Ont., and a Master's degree in landscape architecture at the University of Guelph. Her first job after university involved computer-aided drafting of projects such as ...

  17. African Journal of AIDS Research - Vol 10, No 1 (2011)

    African Journals Online (AJOL)

    Delays in presenting for tuberculosis treatment associated with fear of learning one is HIV-positive · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Valerie Møller, Ida Erstad, Jane M Cramm, Anna P Nieboer, Harry Finkenflügel, Sarah Radloff, Tinashe Ndoro, Stella A Kwizera.

  18. A qualitative analysis of the barriers to antiretroviral therapy initiation ...

    African Journals Online (AJOL)

    A qualitative analysis of the barriers to antiretroviral therapy initiation among children 2 to 18 months of age in Swaziland. Charisse V Ahmed, Pauline Jolly, Luz Padilla, Musa Malinga, Chantal Harris, Nobuhle Mthethwa, Inessa Ba, Amy Styles, Sarah Perry, Raina Brooks, Florence Naluyinda-Kitabire, Makhosini Mamba, ...

  19. Reconsidering Emancipatory Education: Staging a Conversation between Paulo Freire and Jacques Ranciere

    Science.gov (United States)

    Galloway, Sarah

    2012-01-01

    In this essay Sarah Galloway considers emancipation as a purpose for education through examining the theories of Paulo Freire and Jacques Ranciere. Both theorists are concerned with the prospect of distinguishing between education that might socialize people into what is taken to be an inherently oppressive society and education with emancipation…

  20. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 96; Issue 5. J. B. S. Haldane: the John Innes years. SARAH WILMOT. HALDANE AT 125 Volume 96 Issue 5 November 2017 pp 815-826. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jgen/096/05/0815-0826. Keywords. J. B. S. ...

  1. 75 FR 28103 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice

    Science.gov (United States)

    2010-05-19

    ...-3704; Fax: (907) 238-3705; E-mail: [email protected] , [email protected] . Sarah Jenkins, ICWA Social...: (907) 368- 3122; Fax: (907) 368-5401; E-mail: n/a. Point Lay, Native Village of, Sophie Henry, IRA...

  2. Guide to Eating for Sports

    Medline Plus

    Full Text Available ... depends on the individual's age, size, level of physical activity, and environmental temperature. Experts recommend that athletes drink ... different food groups based on age, gender, and activity level. Reviewed by: Sarah R. Gibson, MD Date reviewed: ... Center Sports Physicals Figuring Out Fat and Calories Sports Center Vitamins ...

  3. Evaluation of satellite and reanalysis wind products with in situ wave glider wind observations in the Southern Ocean

    CSIR Research Space (South Africa)

    Schmidt, KM

    2017-12-01

    Full Text Available observations in the Southern Ocean 2 3 Kevin M. Schmidta, Sebastiaan Swartb,c,d, Chris Reasonc, Sarah Nicholsonb,c 4 a Marine Research Institute, University of Cape Town, Rondebosch, South Africa 5 b Southern Ocean Carbon & Climate Observatory, Council...

  4. Control of Disease Recurrence by Tumor-Infiltrating T Cells in Ovarian Cancer

    Science.gov (United States)

    2011-03-01

    size of at least 1 million clonotypes René L. Warren,1 J. Douglas Freeman,1 Thomas Zeng,1 Gina Choe,1 Sarah Munro,1 Richard Moore,1 John R. Webb,2 and...gene therapy. Hum. Gene Ther. 20, 1106. Van Camp, K., Cools, N., Stein, B., Van de Velde, A., Goossens , H., Berneman, Z. N., Van Tendeloo, V., 2010

  5. Global Journal of Educational Research - Vol 16, No 2 (2017)

    African Journals Online (AJOL)

    Managing teachers work safety for quality Service delivery in secondary schools in rivers State · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Emmanuel O. Eseyin, Stalla Chidinma Anieheobi, Sarah Oyemwen Osah, Ololade Adebiyi, 81-86.

  6. Grand Conversations across Texts

    Science.gov (United States)

    Crafton, Linda K., Ed.; Johnson, Nancy J., Ed.

    2008-01-01

    This issue of "School Talk" brings together the ideas of purposefulness and intertextuality together in a teaching practice called intentional intertextual inquiry. "Making Inquiry Intentional and Intertextual" (Karen Smith, Sarah Diaz, and Silvia Edgerton) discusses the framework that combines inquiry-based learning and intertextuality within…

  7. Targeting the S1P Axis and Development of a Novel Therapy for Obesity-Related Triple-Negative Breast Cancer

    Science.gov (United States)

    2015-09-01

    Catherine I. Dumur, Zara Zelenko, Emily J. Gallagher, Derek Leroith, Sheldon Milstien1, Kazuaki Takabe and Sarah Spiegel. The Phosphorylated Prodrug...Akimitsu Yamada, Masayuki Nagahashi, Tomoyoshi Aoyagi, Hiroaki Aoki, Catherine I. Dumur, Zara Zelenko, Emily J. Gallagher, Derek Leroith, Sheldon

  8. African Health Sciences

    African Journals Online (AJOL)

    African Health Sciences is an open access, free online, internationally ... by the African Health Journals Partnership Project that is funded by the US National .... Homa Ahmadzia, Sarah Cigna, Imelda Namagembe, Charles Macri, France ... Workers (HEWs) delivering integrated community case management (iCCM) of ...

  9. Biogenic volatile organic compounds (BVOCs) emissions from Abies alba in a French forest.

    Science.gov (United States)

    Moukhtar, S; Couret, C; Rouil, L; Simon, V

    2006-02-01

    Air quality studies need to be based on accurate and reliable data, particularly in the field of the emissions. Biogenic emissions from forests, crops, and grasslands are now considered as major compounds in photochemical processes. Unfortunately, depending on the type of vegetation, these emissions are not so often reliably defined. As an example, although the silver fir (Abies alba) is a very widespread conifer tree in the French and European areas, its standard emission rate is not available in the literature. This study investigates the isoprene and monoterpenes emission from A. alba in France measured during the fieldwork organised in the Fossé Rhénan, from May to June 2003. A dynamic cuvette method was used. Limonene was the predominant monoterpene emitted, followed by camphene, alpha-pinene and eucalyptol. No isoprene emission was detected. The four monoterpenes measured showed different behaviours according to micrometeorological conditions. In fact, emissions of limonene, alpha-pinene and camphene were temperature-dependant while eucalyptol emissions were temperature and light dependant. Biogenic volatile organic compounds emissions were modeled using information gathered during the field study. Emissions of the three monoterpenes previously quoted were achieved using the monoterpenes algorithm developed by Tingey et al. (1980) [Tingey D, Manning M, Grothaus L, Burns W. Influence of light and temperature on monoterpene emission rates from slash pine. Plant Physiol 1980;65: 797-801.] and the isoprene algorithm [Guenther, A., Monson, R., Fall, R., 1991. Isoprene and monoterpene emission rate variability: observations with eucalyptus and emission rate algorithm development. J Geophys Res 26A: 10799-10808.]; [Guenther, A., Zimmerman, P., Harley, P., Monson, R., Fall, R., 1993. Isoprene and monoterpene emission rate variability: model evaluation and sensitivity analysis. J Geophys Res 98D: 12609-12617.]) was used for the eucalyptol emission. With these

  10. Researching Primary Teachers' Professional Agency: Employing Interactive Ethnography to Overcome Reluctance to Teach Science

    Science.gov (United States)

    Martin, Jenny

    2017-09-01

    This paper provides a report of a case study on the professional agency of an experienced early years teacher, Sarah, who successfully embedded a chemical science program of teaching-learning for her students aged between 6 and 8. Interactive ethnography informs the research design, and discursive psychology provides the tools for the analysis of Sarah's speech acts for her positioning as a responsible agent. Reframing the problem of primary teacher reluctance to teach science in terms of primary teachers' professional agency using discursive psychology, this ontological study provides new insight into issues related to the provision of science education in primary schools and asks: How do primary teachers position themselves and others in relation to science curriculum and education? The research calls for research methodologies and reform efforts in primary science that are better grounded in the local moral orders of primary schools.

  11. Automatic calculation of supersymmetric renormalization group equations and loop corrections

    Science.gov (United States)

    Staub, Florian

    2011-03-01

    SARAH is a Mathematica package for studying supersymmetric models. It calculates for a given model the masses, tadpole equations and all vertices at tree-level. This information can be used by SARAH to write model files for CalcHep/ CompHep or FeynArts/ FormCalc. In addition, the second version of SARAH can derive the renormalization group equations for the gauge couplings, parameters of the superpotential and soft-breaking parameters at one- and two-loop level. Furthermore, it calculates the one-loop self-energies and the one-loop corrections to the tadpoles. SARAH can handle all N=1 SUSY models whose gauge sector is a direct product of SU(N) and U(1) gauge groups. The particle content of the model can be an arbitrary number of chiral superfields transforming as any irreducible representation with respect to the gauge groups. To implement a new model, the user has just to define the gauge sector, the particle, the superpotential and the field rotations to mass eigenstates. Program summaryProgram title: SARAH Catalogue identifier: AEIB_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIB_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 97 577 No. of bytes in distributed program, including test data, etc.: 2 009 769 Distribution format: tar.gz Programming language: Mathematica Computer: All systems that Mathematica is available for Operating system: All systems that Mathematica is available for Classification: 11.1, 11.6 Nature of problem: A supersymmetric model is usually characterized by the particle content, the gauge sector and the superpotential. It is a time consuming process to obtain all necessary information for phenomenological studies from these basic ingredients. Solution method: SARAH calculates the complete Lagrangian for a given model whose

  12. Homme kell 18 avatakse Villa Manini kaasaja kunsti keskuses...

    Index Scriptorium Estoniae

    2004-01-01

    Uue Euroopa foto- ja videokunstinäitus "Instant Europe", kus on väljas kümne hiljaaegu Euroopa Liitu astunud riigi - Küpros, Eesti, Läti, Leedu, Malta, Poola, Tšehhi, Slovakkia, Sloveenia, Ungari - kunstnike tööd. Kuraatorid Francesco Bonami ja Sarah Cosulich Canarutto. Eestit esindavad Jaan Toomik, Kai Kaljo, Ene-Liis Semper ja Liina Siib

  13. Plaadid / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2003-01-01

    Uutest plaatidest Sarah Connor "Unbelievable", Robbie Williams "Escapology", Stan Getz "The Definitive Stan Getz", Santana "Sunrise", Wallflowers "Red Letter Days", Robert Palmer "At His Very Best", INXS "Definitive", Hilary Hahn "Mendelssohn/Shostakovich", System Of A Down "Steal This Album!", Disturbed "Believe", "Divas Las Vegas", Yann Tiersen " C'Etait Ici", We Will Rock You " Original London Cast Recording", Busta Rhymes " It Ain't Safe No More", David Bowie "Best Of", Terence Trent D'Arby "Greatest Hits"

  14. The Guerrillas in the Boardroom: What COIN Theory Teaches Leaders about Organizational Change, and How Corporate Change Models Could Transform Military Doctrine

    Science.gov (United States)

    2016-09-25

    there. When I was at CGSC, students studied two models for organizational change. One was authored by John Kotter, a former Harvard business professor...who had spent nearly 40 years studying what worked and did not work for business leaders trying to transform their organizations. Based on that...counterinsurgents meeting only with key leaders, which is what U.S. doctrine prescribes.31 As Sarah Chayes points out in her book , Thieves of State

  15. Dirty Pop: Contemporary British Painting, Group Exhibition

    OpenAIRE

    Stubbs, Michael

    2013-01-01

    Phil Allen, Peter Ashton Jones, Jake Clark, Richard Clegg, Dan Coombs, Nelson Diplexcito, Nadine Feinson, Mick Finch, Richard Hamilton, Dan Hays, Gavin Lockheart, Andrea Medjesi Jones, David Leeson, Duncan Newton, Sarah Pickstone, Colin Smith, John Stark, Michael Stubbs, James White, Mark Wright.\\ud \\ud Dirty Pop, curated for &Model by Mark Wright, presents twenty contemporary painters whose work connects with Pop Art of the 1960’s, and particularly the legacy of the important British artist ...

  16. Implementation of an Integrated Orthopedic Curriculum to Increase Clinical and Procedural Competency amongst Pediatric Residents

    Science.gov (United States)

    2017-04-05

    to Increase Clinical and Procedural Competency Amongst Pediatric Residents presented at/published to APPD Conference, Anaheim, CA, 5-8 April 2017 in...Increase Clinical and Procedural Competency amongst Pediatric Residents 7. FUNDING RECEIVED FOR THIS STUDY? 0 YES l8] t-’O FUNDING SOURCE 8. DO YOU NEED...and Procedural Competency amongst Pediatric Residents Sarah Nelin MD, Taneishia Jones, MD, Jason Beachler MD, Michelle Lawson MD, Bryan Lawson, MD

  17. State and Individuality: The New Tendencies of the State Action on Behavior

    Directory of Open Access Journals (Sweden)

    Marina Fischer Monteiro de Araujo

    2016-11-01

    Full Text Available There are several teories that seek to analyse and relate the state´s action and the conservation of individuality. With the resumption of paternalistic theories, represented by Coercive Paternalism, by Sarah Conly, and the Libertarian Paternalism by Cass Sustein and Richard Thaler, the world started to give more attention to factors such as de boundaries of tradicional sciences. This work aims to undestand better the paternalistic movement and provide examples of implementations in the brazilian reality.

  18. Statistical Methods for Studying Genetic Variation in Populations

    Science.gov (United States)

    2012-08-01

    iteration will converge to a local optimum, similar to what happens in an EM algorithm. Empirically, a near global optimal can be obtained by multiple...and E Matthysen. Genetic variability and gene flow 131 in the globally , critically-endangered Taita thrush. Conservation Genetics, 1:45–55, 2000. 4.5.2...Libioulle, Edouard Louis, Sarah Hansoul, Cynthia Sandor, Frédéric Farnir, Denis Franchi - mont, Séverine Vermeire, Olivier Dewit, Martine de Vos, Anna

  19. Kuninglikus õukonnateatris. I-IV osa / Jaanus Rohumaa

    Index Scriptorium Estoniae

    Rohumaa, Jaanus, 1969-

    1999-01-01

    Jaanus Rohumaa Londonis Royal Court Theatre' poolt korraldatud residentuuris, mis on mõeldud tänapäeva näitekirjanikele ja lavastajatele. Muljeid kokkutulnud eri maade näitekirjanikest ja lavastajatest. Jaanus Rohumaa lavastab Londonis Royal Shakespeare Company teatris Jaan Tätte näidendit "Ristumine peateega"(II osa) Inglise näitekirjaniku Sarah Kane'i loomingust, Robert Lepage'i lavastusest "Imede geomeetria" (III osa)

  20. Prader–Willi syndrome: clinical problems in transition from pediatric to adult care

    OpenAIRE

    Crinò, Antonino; Fintini,Danilo; Bocchini,Sarah; Carducci,Chiara; Grugni,Graziano

    2016-01-01

    Antonino Crinò,1 Danilo Fintini,1 Sarah Bocchini,1 Chiara Carducci,1 Graziano Grugni,2 1Autoimmune Endocrine Diseases Unit, Bambino Gesù Children’s Hospital, Research Institute, Palidoro, Rome, 2Division of Auxology, Italian Auxological Institute, Research Institute, Piancavallo, Verbania, Italy Abstract: Prader–Willi syndrome (PWS) represents the most common form of genetic obesity. Thanks to the advances in medical care and technology, many...

  1. Prader–Willi syndrome: clinical problems in transition from pediatric to adult care

    OpenAIRE

    Crinò A; Fintini D; Bocchini S; Carducci C; Grugni G

    2016-01-01

    Antonino Crinò,1 Danilo Fintini,1 Sarah Bocchini,1 Chiara Carducci,1 Graziano Grugni,2 1Autoimmune Endocrine Diseases Unit, Bambino Gesù Children’s Hospital, Research Institute, Palidoro, Rome, 2Division of Auxology, Italian Auxological Institute, Research Institute, Piancavallo, Verbania, Italy Abstract: Prader–Willi syndrome (PWS) represents the most common form of genetic obesity. Thanks to the advances in medical care and technology, many persons with PWS li...

  2. Teen Scene Vaccines (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2015-07-30

    Vaccination of infants and toddlers is a common and well-accepted practice in the U.S. However, parents need to be aware of shots that are recommended for preteens. In this podcast, Dr. Sarah Reagan-Steiner discusses the importance of ensuring that older children are up-to-date on their vaccines.  Created: 7/30/2015 by MMWR.   Date Released: 7/30/2015.

  3. Having Healthy Babies (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-01-19

    Most babies in the United States are born perfectly healthy. However, a small percentage are born with birth defects, and these conditions account for one of every five infant deaths in the United States. In this podcast, Dr. Sarah Tinker discusses ways for women to improve their chances of having a healthy baby.  Created: 1/19/2017 by MMWR.   Date Released: 1/19/2017.

  4. 'My job challenges me every day'.

    Science.gov (United States)

    2017-06-14

    After qualifying as a children's nurse at the end of 1990, Brian McGowan worked as a staff nurse in paediatric intensive care before moving on to work in burns and reconstructive surgery. He developed the clinical educator post in Belfast, Northern Ireland and, after a brief stint as a research nurse, was appointed as a lecturer at Ulster University in 2001. He and his wife Fiona have two children, Jack and Sarah.

  5. Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway

    OpenAIRE

    Hodroj,Mohammad Hassan; Jardaly,Achraf; abi Raad,Sarah; Zouein,Annalise; Rizk,Sandra

    2018-01-01

    Mohammad Hassan Hodroj, Achraf Jardaly, Sarah Abi Raad, Annalise Zouein, Sandra Rizk Department of Natural Sciences, Lebanese American University, Beirut, Lebanon Background: Topotecan (TP) is an anticancer drug acting as topoisomerase I inhibitor that is used in the treatment of many types of cancers including leukemia, but it has significant side effects. Andrographolide, a compound extracted from Andrographis paniculata, was recently proven to inhibit the growth of cancer cells and can ind...

  6. Characterization of Psychological and Biological Factors in an Animal Model of Warrior Stress

    Science.gov (United States)

    2013-07-26

    through the ups and downs of grad school. My “older sisters” in the lab, who “ voted me” in, Kristen, Amy, Sarah, Steph, and Cindy, I thank them...Services University, Bethesda, MD 13. Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. 2002. Diffusion tensor MR imaging in...Petersen NJ, Scheibel R, et al. 2010. Diffusion tensor imaging of mild to moderate blast-related traumatic brain injury and its sequelae. J. Neurotrauma 27

  7. Adolescent mental health: Challenges with maternal noncompliance

    OpenAIRE

    Nejtek, Vicki A; Hardy, Sarah; Winter, Scott

    2010-01-01

    Vicki A Nejtek, Sarah Hardy, Scott WinterUniversity of North Texas Health Science Center, Fort Worth, TX, USAAbstract: The leading cause of suicide ideation, attempts, and completion in adolescents is persistent and unresolved parental conflict. National statistics show extremely high rates of childhood neglect and abuse are perpetrated most often by single mothers. Psychiatric disorders arising from maternal–child dysfunction are well-documented. However, resources to prevent offsp...

  8. Fall Events at the NCI Campus at Frederick | Poster

    Science.gov (United States)

    Take a Hike Day – September 19 Occupational Health Services and the R&W Club teamed up again to hold Take a Hike Day on September 19. About 45 employees walked or jogged the 1.3-mile course around Fort Detrick during their lunch hours. The event is designed to encourage employees to engage in physical activity, according to Sarah Hooper, RN, manager of OHS. Sports pouch kits

  9. A Cooperative Communication System for the Advancement of Safe, Effective, and Efficient Patient Care

    Science.gov (United States)

    2015-09-01

    that could inform current diagnoses and treatments. Dr. Nemeth retained Sarah Murray, RN, to serve as Research Nurse for the remainder of the...changes in Phase 3. In Phase 2, we combined several functions into the Charge Nurse Rounds (CRN) View, including Orders, Tasks, and a Checklist...Assessment ( Rescheduled for November 2015) [pending NCE approval] 5. Validation Assessment (Scheduled for January 2016) [pending NCE approval] 6. Tested

  10. A Community College Instructor's Reflective Journey Toward Developing Pedagogical Content Knowledge for Nature of Science in a Non-majors Undergraduate Biology Course

    Science.gov (United States)

    Krajewski, Sarah J.; Schwartz, Renee

    2014-08-01

    Research supports an explicit-reflective approach to teaching about nature of science (NOS), but little is reported on teachers' journeys as they attempt to integrate NOS into everyday lessons. This participatory action research paper reports the challenges and successes encountered by an in-service teacher, Sarah, implementing NOS for the first time throughout four units of a community college biology course (genetics, molecular biology, evolution, and ecology). Through the action research cycles of planning, implementing, and reflecting, Sarah identified areas of challenge and success. This paper reports emergent themes that assisted her in successfully embedding NOS within the science content. Data include weekly lesson plans and pre/post reflective journaling before and after each lesson of this lecture/lab combination class that met twice a week. This course was taught back to back semesters, and this study is based on the results of a year-long process. Developing pedagogical content knowledge (PCK) for NOS involves coming to understand the overlaps and connections between NOS, other science subject matter, pedagogical strategies, and student learning. Sarah found that through action research she was able to grow and assimilate her understanding of NOS within the biology content she was teaching. A shift in orientation toward teaching products of science to teaching science processes was a necessary shift for NOS pedagogical success. This process enabled Sarah's development of PCK for NOS. As a practical example of putting research-based instructional recommendations into practice, this study may be very useful for other teachers who are learning to teach NOS.

  11. How Should Air Force Expeditionary Medical Capabilities Be Expressed

    Science.gov (United States)

    2009-01-01

    Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Sci- ence, Vol. 4, 2006, pp. 135–146; Sarah A. Lister, Hurricane Katrina: The Public...setting this might mean releasing the patient to a nursing home. In a domestic civilian disaster setting, it may mean releasing the patient to some...described below. The Mobile Aeromedical Staging Facility (MASF) is a 15-person, communications-capable UTC that provides supportive/resuscita- tive nursing

  12. Spectacular Subjects : Race, Rhetoric, and Visuality in American Public Cultures (1870-1900)

    OpenAIRE

    Jabour, Tania Nicole

    2015-01-01

    Spectacular Subjects engages with the campaigns of three activists who inserted themselves into the nineteenth century American public sphere to combat forces of exploitation and disfranchisement in the communities they came to represent. The project is divided into three chapters, which correspond to the figures profiled : Ida B. Wells, an African American anti-lynching crusader; Sarah Winnemucca, a Native American advocate for reservation reform; and Wong Chin Foo, a Chinese American journa...

  13. Le futur du travail | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12 juin 2017 ... Trois hommes qui travaillent sur le projet de livraison de drone au Rwanda. Sarah Farhat / Banque mondiale. La numérisation, l'automatisation et les communications en réseau façonnent de plus en plus les sociétés, les marchés du travail et les occasions d'emploi à l'échelle mondiale. Les changements ...

  14. Ikka PÖFFist, 13. korda / Helmut Jänes

    Index Scriptorium Estoniae

    Jänes, Helmut, 1972-

    2009-01-01

    13. Pimedate Ööde Filmifestival Tallinnas. Võistlusfilmid: "Minu aasta ilma seksita" (Austraalia; režissöör Sarah Watt), "Laila sünnipäev" (Palestiina-Tuneesia-Holland; režissöör Rashid Masharawi), "Emma Blanki viimased päevad" (Holland; režissöör Alex van Warmerdam), "Sinihabe" (Prantsusmaa; režissöör Catherine Breillat)

  15. Det er fullt her inne!

    OpenAIRE

    Hay, Simen Formo

    2018-01-01

    Program og foto. Teaterforestilling vist 12., 13., 14., 16.-18. april 2018 på Seilduken Scene 6 Bacheloroppgave i regi, fra Teaterhøgskolen, med regi av Simen F.H.. Et avgangsprosjekt, med skuespillerne Ina Svenningdal, Sindre Hansen, Sarah Francesca Brænne, Brede Fristad, William Greni Arnø, Lars Halvor Andreassen. Bandet Elon Musk deltar, og kleskolleksjon lanseres av Alva Brosten / Hijacked. Foto: S. Hutton?

  16. Transient Nonlinear Optical Properties of Thin Film Titanium Nitride

    Science.gov (United States)

    2017-03-23

    13] • Chemical composition • Crystal structure and lattice parameters • Defect structure This tuneability will be useful in future engineering ...Nitride SarahKatie Thomas Follow this and additional works at: https://scholar.afit.edu/etd Part of the Materials Science and Engineering Commons This... Thesis is brought to you for free and open access by AFIT Scholar. It has been accepted for inclusion in Theses and Dissertations by an authorized

  17. Seriedrømme

    DEFF Research Database (Denmark)

    Ion Wille, Jakob

    2016-01-01

    narrative indhold og karakterernes handlinger. Mange vil sikkert tænke på Sarah Lunds islandske uldsweater i tv-serien Forbrydelsen (2007-2012) som et eksempel på ikonisk design, fordi den knytter sig så tæt til hendes karakters samlede udtryk. Mindre fokuseret, men mindst lige så væsentlig for seriens...

  18. Years after Inventors Die, Royalties Are Pennies from Heaven

    Science.gov (United States)

    Blumenstyk, Goldie

    2009-01-01

    Sarah L. Kieweg had her own nice surprise when the University of Central Florida contacted her. She understood quite a bit about her father's pioneering work on artificial intelligence in the 1990s. Still, in 2006, eight years after he died of a heart attack, at age 50, the call from the university came out of the blue: some of James R. Driscoll's…

  19. Project Portal User-Centered Design and Engineering Report

    Science.gov (United States)

    2016-06-01

    TECHNICAL REPORT 3013 June 2016 Project Portal User-Centered Design and Engineering Report Deborah Gill-Hesselgrave Veronica Higgins Sarah...Design and Engineering Branch Under authority of Chris Raney, Head Command and Control Technology and Experiments Division iii EXECUTIVE...navy.mil  Christian Szatkowski christian.szatkowski@navy.mil  Roni Higgins roni.higgins@navy.mil  Jake Viraldo jacob.viraldo@navy.mil B

  20. Teachers and Content Area Reading: Attitudes, Beliefs and Change

    Science.gov (United States)

    Hall, L.A.

    2005-01-01

    ''Sometimes the teacher will say, 'Read to the bottom of the page,' and I try but I fall behind. Then she asks questions and a whole bunch of kids can answer the questions but I can't. I try to keep up with everything but it's really hard. Sarah; 6th grade social studies student''. This paper presents the results of a review of the research into…

  1. L΄artiste et ses perceptions: vers une nouvelle théorie de l΄art

    Directory of Open Access Journals (Sweden)

    Victor Anches

    2012-06-01

    Full Text Available Review to: Konrad Fiedler, Sur l’origine de l’activité artistique, deuxième édition, traduit par Inès Rotermund, Sarah Schmidt, Werner Uwer, Sacha Zilberfarb, sous la direction de Danièle Cohn, Ileana Parvu. Paris: Editions Rue d’Ulm/Presses de l’Ecole normale supérieure, 2008

  2. Isotopic and chemical investigations of quaternary aquifer in sinai peninsula

    International Nuclear Information System (INIS)

    Sadek, M.A.; Ahmed, M.A.; Awad, M.A.

    2001-01-01

    The present study has been conducted to investigate the renewal activity and mineralization potential of the quaternary aquifer in Sinai peninsula using environmental isotopes and hydrochemistry. The quaternary aquifer is vital for development processes as it has a wide extension and shallow water table. The total dissolved salts vary greatly from one location to another and range widely between 510-7060 mg/1, reflecting all categories from fresh to saline water. The change in salinity all over Sinai can be attributed to variations in the rate of evaporation. Leaching and dissolution of terrestrial salts during floods as well as the effects of sea spray and saline water intrusion. The main sources of groundwater recharge are the infiltration of Local precipitation and surface runoff as well as lateral flow through hydraulic connection with fractured aquifers. Snow melt also contributes to aquifer recharge in some areas in the central part of southern Sinai. The environmental stable isotopic contents of the ground water in the quaternary aquifer in Sinai reflect the isotopic composition of rain water from continental and east Mediterranean precipitation and monsonal air mass which comes from Indian ocean as well as the seepage of partly evaporated floodwater. The southern samples are more suitable for drinking and irrigation purposes due to its lower salinity and sodium hazard

  3. Architectural elements and bounding surfaces in fluvial deposits: anatomy of the Kayenta formation (lower jurassic), Southwest Colorado

    Science.gov (United States)

    Miall, Andrew D.

    1988-03-01

    Three well-exposed outcrops in the Kayenta Formation (Lower Jurassic), near Dove Creek in southwestern Colorado, were studied using lateral profiles, in order to test recent regarding architectural-element analysis and the classification and interpretation of internal bounding surfaces. Examination of bounding surfaces within and between elements in the Kayenta outcrops raises problems in applying the three-fold classification of Allen (1983). Enlarging this classification to a six-fold hierarchy permits the discrimination of surfaces intermediate between Allen's second- and third-order types, corresponding to the upper bounding surfaces of macroforms, and internal erosional "reactivation" surfaces within the macroforms. Examples of the first five types of surface occur in the Kayenta outcrops at Dove Creek. The new classifications is offered as a general solution to the problem of description of complex, three-dimensional fluvial sandstone bodies. The Kayenta Formation at Dove Creek consists of a multistorey sandstone body, including the deposits of lateral- and downstream-accreted macroforms. The storeys show no internal cyclicity, neither within individual elements nor through the overall vertical thickness of the formation. Low paleocurrent variance indicates low sinuosity flow, whereas macroform geometry and orientation suggest low to moderate sinuosity. The many internal minor erosion surfaces draped with mud and followed by intraclast breccias imply frequent rapid stage fluctuation, consistent with variable (seasonal? monsonal? ephemmeral?) flow. The results suggest a fluvial architecture similar to that of the South Saskatchewan River, through with a three-dimensional geometry unlike that interpreted from surface studies of that river.

  4. Dynamic mean field theory for lattice gas models of fluid mixtures confined in mesoporous materials.

    Science.gov (United States)

    Edison, J R; Monson, P A

    2013-11-12

    We present the extension of dynamic mean field theory (DMFT) for fluids in porous materials (Monson, P. A. J. Chem. Phys. 2008, 128, 084701) to the case of mixtures. The theory can be used to describe the relaxation processes in the approach to equilibrium or metastable equilibrium states for fluids in pores after a change in the bulk pressure or composition. It is especially useful for studying systems where there are capillary condensation or evaporation transitions. Nucleation processes associated with these transitions are emergent features of the theory and can be visualized via the time dependence of the density distribution and composition distribution in the system. For mixtures an important component of the dynamics is relaxation of the composition distribution in the system, especially in the neighborhood of vapor-liquid interfaces. We consider two different types of mixtures, modeling hydrocarbon adsorption in carbon-like slit pores. We first present results on bulk phase equilibria of the mixtures and then the equilibrium (stable/metastable) behavior of these mixtures in a finite slit pore and an inkbottle pore. We then use DMFT to describe the evolution of the density and composition in the pore in the approach to equilibrium after changing the state of the bulk fluid via composition or pressure changes.

  5. A trip to Rome—thanks to antimatter

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Angels and Demons exhibition created by the PH Department’s Education Group came to an end last summer. The exhibition was accompanied by a competition, with a first prize of a flight to Rome. Now we know the winner’s name. An exhibit of the Angels&Demons - the science behind the story exhibition She is Sarah Manton, and she is from Scotland. In September Sarah will fly to Rome with her husband to retrace the Angels and Demons street itinerary. “We are looking forward to visiting the usual tourist sights, including all the places that feature in Angels and Demons such as the Pantheon,” she said in answer to a question from the exhibition organisers. The couple was touring CERN when, intrigued by the Globe and the name of the exhibition, they decided to do a visit and participate in the competition. Five correct answers on antimatter later—and several months on—Sarah got a pleasant surprise: “I decided to have a go at the quiz an...

  6. Cine Club

    CERN Multimedia

    Cine Club

    2015-01-01

    Wednesday 16 December 2015 at 20:00 CERN Council Chamber Love Streams Directed by John Cassavetes USA, 1984, 141 minutes The film describes a few days in the life of the writer Robert Harmon and his sister Sarah. The decadent life of Robert is made of alcohol, cigarettes, and short-time relationships with women; women he interviews for a book, he spends a weekend with at a casino or falls in love with for the fun of an evening. Having no constraints, he is unable to be responsible for anything including the care of his son, leaving him alone in a hotel room and teaching the 8-year-old boy how to drink. His life is made of his own phantasms as an artist. His sister is divorcing from her husband because of her exuberant and insane behaviour. She scares her daughter Debbie who prefers to stay with her father, a decision that hurts Sarah very deeply and reinforces her nervous breakdown. Most of the movie takes place in the house of Robert. We watch Robert and Sarah struggling with their own lives. As the movie...

  7. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    International Nuclear Information System (INIS)

    Staub, Florian; Athron, Peter; Basso, Lorenzo

    2016-02-01

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model.

  8. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    Energy Technology Data Exchange (ETDEWEB)

    Staub, Florian [CERN, Theoretical Physics Department, Geneva (Switzerland); Athron, Peter [Monash University, ARC Centre of Excellence for Particle Physics at the Terascale, School of Physics, Melbourne, VIC (Australia); Basso, Lorenzo [CPPM, Aix-Marseille Universite, CNRS-IN2P3, UMR 7346, Marseille Cedex 9 (France); Goodsell, Mark D. [Sorbonne Universites, LPTHE, UMR 7589, CNRS and Universite Pierre et Marie Curie, Paris Cedex 05 (France); Harries, Dylan [The University of Adelaide, Department of Physics, ARC Centre of Excellence for Particle Physics at the Terascale, Adelaide, SA (Australia); Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby [Bethe Center for Theoretical Physics and Physikalisches Institut der Universitaet Bonn, Bonn (Germany); Ubaldi, Lorenzo [Tel-Aviv University, Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv (Israel); Vicente, Avelino [Instituto de Fisica Corpuscular (CSIC-Universitat de Valencia), Valencia (Spain); Voigt, Alexander [Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)

    2016-09-15

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model. (orig.)

  9. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    Energy Technology Data Exchange (ETDEWEB)

    Staub, Florian [CERN, Geneva (Switzerland). Theoretical Physics Dept.; Athron, Peter [Monash Univ., Melbourne (Australia). ARC Center of Excellence for Particle Physics at the Terascale; Basso, Lorenzo [Aix-Marseille Univ., CNRS-IN2P3, UMR 7346 (France). CPPM; and others

    2016-02-15

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model.

  10. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    CERN Document Server

    Staub, Florian; Basso, Lorenzo; Goodsell, Mark D.; Harries, Dylan; Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby; Ubaldi, Lorenzo; Vicente, Avelino; Voigt, Alexander

    2016-09-23

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective...

  11. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    International Nuclear Information System (INIS)

    Staub, Florian; Athron, Peter; Basso, Lorenzo; Goodsell, Mark D.; Harries, Dylan; Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby; Ubaldi, Lorenzo; Vicente, Avelino; Voigt, Alexander

    2016-01-01

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model. (orig.)

  12. The Abrupt Onset of the Modern South Asian Monsoon Winds (iodp Exp. 359)

    Science.gov (United States)

    Betzler, C.; Eberli, G. P.; Kroon, D.; Wright, J. D.; Swart, P. K.; Nath, B. N.; Reijmer, J.; Alvarez Zarikian, C. A.

    2016-12-01

    The South Asian Monson (SAM) is one of the most extreme features in Earth's climate system, yet its initiation and variations are not well established. The SAM is a seasonal reversal of winds accompanied by changes in precipitation with heavy rain during the summer monsoon. It is one of the most intense annually recurring climatic elements and of immense importance in supplying moisture to the Indian subcontinent thus affecting human population and vegetation, as well as marine biota in the surrounding seas. The seasonal precipitation change is one of the SAM elements most noticed on land, whereas the reversal of the wind regime is the dominating driver of circulation in the central and northern Indian Ocean realm. New data acquired during International Ocean Discovery Program Expedition 359 from the Inner Sea of the Maldives provide a previously unread archive that reveals an abrupt onset of the SAM-linked ocean circulation pattern and its relationship to the long term Neogene climate cooling. In particular it registers ocean current fluctuations and changes of intermediate water mass properties for the last 25 myrs that are directly related to the monsoon. Dating the deposits of SAM wind-driven currents yields an age of 12.9 Ma indicating an abrupt SAM onset, over a short period of 300 kyrs. This coincided with the Indian Ocean Oxygen Minimum Zone expansion as revealed by geochemical tracers and the onset of upwelling reflected by the sediment's content of sedimentary organic matter. A weaker `proto-monsoon' existed between 12.9 and 25 Ma, as mirrored by the sedimentary signature of dust influx. Abrupt SAM initiation favors a strong influence of climate in addition to the tectonic control, and we propose that the post Miocene Climate Optimum cooling, together with increased continentalization and establishment of the bipolar ocean circulation, i.e. the beginning of the modern world, shifted the monsoon over a threshold towards the modern system.

  13. Partner Accommodation Moderates Treatment Outcomes for Couple Therapy for Posttraumatic Stress Disorder

    Science.gov (United States)

    Fredman, Steffany J.; Pukay-Martin, Nicole D.; Macdonald, Alexandra; Wagner, Anne C.; Vorstenbosch, Valerie; Monson, Candice M.

    2015-01-01

    Objective Partner accommodation of posttraumatic stress disorder (PTSD) symptoms (i.e., altering one’s own behaviors to minimize patient distress and/or relationship conflict due to patients’ PTSD symptoms) has been shown to be positively associated with patient and partner psychopathology and negatively associated with patient and partner relationship satisfaction cross-sectionally. However, the prognostic value of partner accommodation in treatment outcomes is unknown. The goals of the present study were to determine if partner accommodation decreases as a function of couple therapy for PTSD and if pretreatment partner accommodation moderates the efficacy of couple therapy for PTSD. Method Thirty-nine patients with PTSD and their intimate partners (n = 39) were enrolled in a randomized controlled trial of cognitive-behavioral conjoint therapy (CBCT) for PTSD (Monson & Fredman, 2012) and received CBCT for PTSD immediately or after three months of waiting. Blinded assessors determined clinician-rated PTSD symptoms and patient-rated PTSD and depressive symptoms and relationship satisfaction at baseline, mid-treatment/4 weeks of waiting, and posttreatment/12 weeks of waiting. Results Contrary to expectation, partner accommodation levels did not change over time for either treatment condition. However, baseline partner accommodation significantly moderated treatment outcomes. Higher levels of partner accommodation were associated with greater improvements in PTSD, depressive symptoms, and relationship satisfaction among patients receiving CBCT for PTSD compared with waiting list. At lower levels of partner accommodation, patients in both groups improved or remained at low levels of these outcomes. Conclusions Individuals with PTSD who have more accommodating partners may be particularly well-suited for couple therapy for PTSD. PMID:26501498

  14. Extensive validation of CM SAF surface radiation products over Europe.

    Science.gov (United States)

    Urraca, Ruben; Gracia-Amillo, Ana M; Koubli, Elena; Huld, Thomas; Trentmann, Jörg; Riihelä, Aku; Lindfors, Anders V; Palmer, Diane; Gottschalg, Ralph; Antonanzas-Torres, Fernando

    2017-09-15

    This work presents a validation of three satellite-based radiation products over an extensive network of 313 pyranometers across Europe, from 2005 to 2015. The products used have been developed by the Satellite Application Facility on Climate Monitoring (CM SAF) and are one geostationary climate dataset (SARAH-JRC), one polar-orbiting climate dataset (CLARA-A2) and one geostationary operational product. Further, the ERA-Interim reanalysis is also included in the comparison. The main objective is to determine the quality level of the daily means of CM SAF datasets, identifying their limitations, as well as analyzing the different factors that can interfere in the adequate validation of the products. The quality of the pyranometer was the most critical source of uncertainty identified. In this respect, the use of records from Second Class pyranometers and silicon-based photodiodes increased the absolute error and the bias, as well as the dispersion of both metrics, preventing an adequate validation of the daily means. The best spatial estimates for the three datasets were obtained in Central Europe with a Mean Absolute Deviation (MAD) within 8-13 W/m 2 , whereas the MAD always increased at high-latitudes, snow-covered surfaces, high mountain ranges and coastal areas. Overall, the SARAH-JRC's accuracy was demonstrated over a dense network of stations making it the most consistent dataset for climate monitoring applications. The operational dataset was comparable to SARAH-JRC in Central Europe, but lacked of the temporal stability of climate datasets, while CLARA-A2 did not achieve the same level of accuracy despite predictions obtained showed high uniformity with a small negative bias. The ERA-Interim reanalysis shows the by-far largest deviations from the surface reference measurements.

  15. Short outlines of books by Estonian authors / Rutt Hinrikus, Janika Kronberg

    Index Scriptorium Estoniae

    Hinrikus, Rutt, 1946-

    2000-01-01

    Andres Ehin. Alateadvus on alatasa purjus; Peeter Torop. Kultuurimärgid; Matt Barker. Sarah' jalad; Jaan Isotamm. Mina Johnny B.; Jaan Kaplinski. Silm. Hektor; Jaan Kaplinski. Kevad kahel rannikul ehk tundeline teekond Ameerikasse; Rein Raud. Pisiasjad, mis omavad tähtsust; Kerttu Rakke. Kalevipoeg; Elin Toona. Rõõm teeb taeva taga tuld; Veera Saar. Neid ammuseid aegu; Toomas Vint. Nädalavahetusel. Mängides; Varjatud ilus haigus : valik sajandilõpu eesti luuletajaid / koostanud Kajar Pruul; Viiu Härm. Duubel kaks

  16. Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer

    Science.gov (United States)

    2016-10-01

    Institutes of Health 900 Rockville Pike Bethesda, MD 20892 Phone : (240) 276-6280 15 E-mail: sarah.lee@nih.gov 1 R01 CA179170-02 (PI: Ronai, Z.) 09/30...Cammie La National Institutes of Health 9000 Rockville Pike Bethesda, MD 20892 Phone : (240) 276-6323 E-mail: cl311z@nih.gov 1 R01 CA172017-02...PI: Ronai, Z.) 07/01/13–04/30/16 1.2 calendar (10.0%) NIH/NCI ATF2 Oncogenic Addiction in Melanoma Goals: The major goal of this project is to

  17. Evaluation of Biomarkers Predictive of Benefit from the PD-1 Inhibitor MK-3475 in Patients with Non-Small Cell Lung Cancer and Brain Metastases

    Science.gov (United States)

    2017-07-01

    Small Cell Lung Cancer and Brain Metastases PRINCIPAL INVESTIGATOR: Sarah B. Goldberg, MD CONTRACTING ORGANIZATION: Yale University New Haven, CT...benefit in patients with non- small cell lung cancer (NSCLC). However, the overall response rate is only 20-30% and there is no clearly-defined...9. Appendices……………………………………………………………14 4 1. INTRODUCTION: Lung cancer is the leading cause of cancer death in the United States, resulting in more

  18. Legal protection of the underwater cultural heritage: lessons from the Titanic

    OpenAIRE

    Dromgoole, Sarah

    2005-01-01

    Dr Sarah Dromgoole (Reader in Law, University of Leicester) charts the history of the legal protection of the underwater cultural heritage and considers some of the lessons that can be learnt from developments in respect of the remains of RMS Titanic. One or two issues of an ethical nature are also explored. Article based on a lecture delivered at the IALS in June 2005 and published in Amicus Curiae - Journal of the Society for Advanced Legal Studies. The Journal is produced by the Society fo...

  19. Layering of life (Sara novel of Peter Sarić)

    OpenAIRE

    Kostić, Dragomir J.

    2015-01-01

    Novel Sara of Petar Sarić consists of two parts; in it are processed or present two wars, two major wars in the region of Montenegro and Herzegovina, the First and Second World War. However, it is more novel about divisions within the family and the man himself, (and infamous assault of godfather Luka on Sarah also and his murder are in that function), in the first part; and on the divisions among the people, in general, in the second part of the novel. The second part is, in fact, the image ...

  20. Refugees Flexing Social Power as Agents of Stability: Creating Modes of Economic Livelihoods in Kenya’s Camps

    Science.gov (United States)

    2017-11-21

    Creating Modes of Economic Livelihoods in Kenya’s Camps Co ns tr uc tio n En gi ne er in g R es ea rc h La bo ra to ry Lance L. Larkin and Sarah A...November 2017 Refugees Flexing Social Power as Agents of Stability Creating Modes of Economic Livelihoods in Kenya’s Camps Lance L. Larkin and...understanding shows that refugee camp citizens harness their own social power, acting as agents of social and economic stability within the country

  1. Leadership among people who use AAC: ISAAC's Project LEAD

    CSIR Research Space (South Africa)

    Bryen, DN

    2008-08-01

    Full Text Available stream_source_info Bryen_2008.pdf.txt stream_content_type text/plain stream_size 23272 Content-Encoding UTF-8 stream_name Bryen_2008.pdf.txt Content-Type text/plain; charset=UTF-8 Leadership in ISAAC: Leading the Way... Diane Nelson Bryen, USA Sarah Lever, USA Sayomdeb Mujherjee, India Martin Pistorius, South Africa Melinda Smith, Australia Leading the Way � square6 Powerful conference title square6 Important call for leadership development Across the Globe...

  2. Mindfulness training applied to addiction therapy: insights into the neural mechanisms of positive behavioral change

    OpenAIRE

    Garland, Eric; Howard,Matthew; Priddy,Sarah; McConnell,Patrick; Riquino,Michael; Froeliger,Brett

    2016-01-01

    Eric L Garland,1,2 Matthew O Howard,3 Sarah E Priddy,1 Patrick A McConnell,4 Michael R Riquino,1 Brett Froeliger4 1College of Social Work, 2Hunstsman Cancer Institute, University of Utah, Salt Lake City, UT, USA; 3School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 4Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA Abstract: Dual-process models from neuroscience suggest that addiction is driven by dysregulated interact...

  3. Physiological and training characteristics of recreational marathon runners

    OpenAIRE

    Gordon, Dan; Wightman, Sarah; Basevitch, Itay; Johnstone, James; Espejo-Sanchez, Carolina; Beckford, Chelsea; Boal, Mariette; Scruton, Adrian; Ferrandino, Mike; Merzbach, Viviane

    2017-01-01

    Dan Gordon,1 Sarah Wightman,2 Itay Basevitch,1 James Johnstone,1 Carolina Espejo-Sanchez,1 Chelsea Beckford,1 Mariette Boal,1 Adrian Scruton,1 Mike Ferrandino,1 Viviane Merzbach1 1Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, 2The Flying Runner, Cambridge, UK Purpose: The aim of this study was to examine the physical and training characteristics of recreational marathon runners within finish time bandings (2.5–3 h, 3–3.5 h, 3...

  4. From Diagnosis to Gnosis: writing, knowledge, and repair in breast cancer and BRCA memoirs.

    Science.gov (United States)

    Boesky, Amy

    2015-01-01

    This essay explores the reparative work of diagnostic retellings in breast cancer and BRCA memoirs (memoirs written by women who learn they carry a mutation predisposing them to develop breast or ovarian cancers). It considers four memoirists (Felicia Knaul, Melanie Norton, Masha Gessen, and Sarah Gabriel) as they illuminate initial moments of "finding out"--learning they have cancer or have tested positive for a BRCA mutation. These memoirists invite readers to appreciate the complexity of cancer as a lived experience. Writing about breast cancer and the risk of its development helps writers and readers alike to understand illness in greater depth, challenging some aspects of care and championing others.

  5. Recent Patterns of Population Change in America’s Urban Places,

    Science.gov (United States)

    1980-08-01

    0 00w a 0 0 3c 0 ON * 00 * Qj C) m 0 C\\ 0 N 4 N .- C𔃾-4 ..- 9 AI bo 0 0 u a, f~00 0~ ~~~ 0\\ 0 0~ 0Y w~ 0 f4 0)J CNCD G)40 & 00CC hi -C 0 22 0 00c log...Left Behind: Population Trends and Policy for Rural America," Rural Sociology, 36, 4: 449-470. Fuguitt, Glen V. and Calvin L. Beale, 1978, "Population...Redistribution in Nonmetropolitan Areas," in Sarah Mills (ed.), Population Distribution and Policy , Commission on Population Growth and the American Future

  6. SHERPA: A systematic human error reduction and prediction approach

    International Nuclear Information System (INIS)

    Embrey, D.E.

    1986-01-01

    This paper describes a Systematic Human Error Reduction and Prediction Approach (SHERPA) which is intended to provide guidelines for human error reduction and quantification in a wide range of human-machine systems. The approach utilizes as its basic current cognitive models of human performance. The first module in SHERPA performs task and human error analyses, which identify likely error modes, together with guidelines for the reduction of these errors by training, procedures and equipment redesign. The second module uses a SARAH approach to quantify the probability of occurrence of the errors identified earlier, and provides cost benefit analyses to assist in choosing the appropriate error reduction approaches in the third module

  7. Radio listening in a life-historical perspective

    DEFF Research Database (Denmark)

    Blaakilde, Anne Leonora

    are interpreted as material-semiotic interactions, as well as the embodied and subjective experiences and memories in time and space are interpreted in a postphenomenological perspective. Encompassing these rather different theories is the notion of soundscape (Schafer) which, in a newer reading inspired by John...... things matter. UCL Press, London. Pink, Sarah and Mackley, Kerstin Leder 2013. Saturated and situated: expanding the meaning of media in the routines of everyday life. Media Culture Society, vol. 35, no. 6: 677-691. Schafer, R. Murray 1994. The Soundscape: Our Sonic Environment and the Tuning...

  8. Searching African skies the square kilometre array and South Africa's quest to hear the songs of the stars

    CERN Document Server

    Wild, Sarah

    2012-01-01

    An ambitious scientific project is unfolding in the desert of South Africa, with a multi-decade timeline that will eventually see expansion into Western Australia-a project that is detailed and celebrated in this book on the Square Kilometre Array (SKA). The SKA will be the largest and most sensitive radio telescope, expanding the capabilities of scientific probing and addressing significant unanswered questions about the universe, such as on the formation of galaxies and the nature of gravity. Keen technology correspondent Sarah Wild covers the important development with this exploration of i

  9. Vesicular stomatitis virus modified with single chain IL-23 exhibits oncolytic activity against tumor cells in vitro and in vivo

    OpenAIRE

    Reiss, Carol Shoshkes

    2010-01-01

    James M Miller1, Sarah McNulty Bidula1,5, Troels Mygind Jensen1,6, Carol Shoshkes Reiss1,2,3,41Department of Biology, New York University, New York, NY, USA; 2Center for Neural Science, NYU; 3NYU Cancer Institute; 4Departments of Microbiology, NYU School of Medicine and Mt Sinai School of Medicine, New York, NY, USA; 5Present address Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA,USA 6Present address: Univercity of Copenhagen, Copenhagen, DenmarkAbstract: Viruse...

  10. Il volto crudele del nemico. Figure di terroristi nella letteratura israeliana

    Directory of Open Access Journals (Sweden)

    Sara Ferrari

    2012-11-01

    Full Text Available The aim of this lecture is to explore the question of representing terrorists in Israeli literature, namely in the books, Ha-me’ahev, (The Lover, by A.B. Yehoshua, Ha-Qaytanah Shel Kneller (Kneller Happy Camp by Etgar Keret, Shum gemadim lo yavo’u (The King of Falafel by Sarah Shilo and Tanin pigua (Croc attack by Assaf Gavron. A particular attention will be devoted to the confrontation with the other and its purpose in these books.

  11. The Twitter Book

    CERN Document Server

    O'Reilly, Tim

    2009-01-01

    This practical guide will teach you everything you need to know to quickly become a Twitter power user, including strategies and tactics for using Twitter's 140-character messages as a serious--and effective--way to boost your business. Co-written by Tim O'Reilly and Sarah Milstein, widely followed and highly respected Twitterers, the practical information in The Twitter Book is presented in a fun, full-color format that's packed with helpful examples and clear explanations.A Sneak Preview on SlideShare

  12. Tervetuloa mun päivään - ja elämään! : yksityisen ja julkisen rajanteko suomalaisten nais- ja miestubettajien my day -videoilla

    OpenAIRE

    Roiha, Paula

    2017-01-01

    Tässä tutkimuksessa tutkitaan, miten tubettajat ylittävät yksityinen/julkinen -dualismia YouTuben my day -videoilla. Tutkimuksen lähtökohtana on Sarah Michele Fordin teoria julkisesta ja yksityisestä jatkumona. Ford liittää yksityiseen ja julkiseen sekä tilallisen että henkilökohtaisen ulottuvuuden. Tältä pohjalta aineistoa tarkasteltiin kuvauspaikkojen sekä videoilla käsiteltyjen aiheiden kautta. Teoriataustassa hyödynnetään myös Sari Näreen käsitteitä yksityisestä, intiimistä ja integriteet...

  13. Screwed Up

    DEFF Research Database (Denmark)

    2014-01-01

    About the (Im)material Artefacts project by Sarah Younan: Emerging digital technologies provide new ways to engage with artefacts and recent developments in 3D print are rapidly bridging the gap between digital and physical objects. For the (Im)material Artefacts project ceramic artefacts from...... practice Hansen combines digital processing with an intuitive grasp of form and materials. Hansen develops software and models his born-digital objects from scratch before 3D printing them. His participation in the (Im)material Artefacts project presented Hansen with a different challenge; to re...

  14. Impact of Obesity on Tamoxifen Chemoprevention in a Model of Ductal Carcinoma in Situ

    Science.gov (United States)

    2012-10-01

    Sarah M. Smith. McDonald JM*, Dunlap SM*, Cogdell D, Dunmire V, Wei Q, Starzinski-Powitz A, Sawaya R, Bruner J, Fuller GN, Aldape K, and Zhang W...Sciences 104(28):11736-41, July 2007. Moore LM, Holmes KM, Smith SM, Wu Y, Tchougounova E, Uhrbom L, Sawaya R, Bruner JM, Fuller GN, and Zhang W... Bruner JM Kuang J, Yu H, Fuller GN and Zhang W. Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP. Oncogene 29(24):3501-8, June

  15. Interview with Bradley Quinn

    OpenAIRE

    Clarke, Sarah E. Braddock; Quinn, Bradley

    2012-01-01

    Sarah E. Braddock Clarke is an author, curator and consultant who lectures at University College Falmouth in Cornwall, where she works on the Fashion Design and\\ud Performance Sportswear Design B.A. (Hons) Degrees. Co-author of SportsTech and coauthor of Techno Textiles 1 and 11, Braddock Clarke is a leading expert in the field of\\ud fashion and performance sportswear. Her research focuses on emerging technologies and new materials, and explores the impact of digital media on textiles created...

  16. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent

    2015-01-01

    INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin...... in the management of patients in warfarintreatment provided good quality of care. Sampling intervaland diagnostic coding were significantly correlated withtreatment quality. FUNDING: The study received financial support from theSarah Krabbe Foundation, the General Practitioners’ Educationand Development Foundation...

  17. Desempenho de cultivares de couve-flor de verão em Ipameri Performance of cultivars of cauliflower summer in Ipameri

    Directory of Open Access Journals (Sweden)

    Odilon Peixoto de Morais Júnior

    2012-11-01

    Full Text Available Com o propósito de avaliar o comportamento de seis cultivares de couve-flor de verão, quanto à produção e resistência à podridão negra (Xanthomonas campestris pv. campestris, instalou-se um experimento em campo, em Ipameri-GO, com o delineamento experimental em blocos completos casualizados com seis tratamentos e quatro repetições. Cada parcela experimental, de 10m², constou de 20 plantas distribuídas no espaçamento de 1,0m entre linhas e 0,5m entre plantas. Foram avaliadas as cultivares: híbridos 'Cindy', 'Sarah AF-1169', 'Sharon', 'Verona', 'Lisvera' e a variedade Piracicaba precoce. Os híbridos Verona e Sharon mostraram-se promissores para cultivo nas condições edafoclimáticas em que foram avaliados, com produtividades de 34,17 e 30,64t ha-1, respectivamente, e com moderados níveis de resistência à podridão negra. A variedade Piracicaba precoce apresentou produção inferior às dos melhores híbridos avaliados e moderada resistência à podridão negra. O híbrido Sarah não é recomendado para plantio na região de Ipameri-GO por apresentar baixa produção e baixa resistência à podridão negra.In order to evaluate the behavior of six cultivars of cauliflower summer, as production and resistance to black rot (Xanthomonas campestris pv. campestris, installed a field experiment in Ipameri-GO, with the experimental in randomized complete blocks with six treatments and four replications. Each plot of 10m², consisting of 20 plants distributed at a spacing of 1.0m between rows and 0.5m between plants. We evaluated the cultivars: hybrids 'Cindy', 'Sarah AF-1169', 'Sharon', 'Verona', 'Lisvera' and the variety Piracicaba precoce. Hybrids Verona and Sharon proved promising for cultivation in the environmental conditions that were evaluated, with yields of 34.17 and 30.64t ha-1 respectively, and moderate levels of resistance to black rot. The variety Piracicaba precoce showed lower production of the best hybrids and moderate

  18. Deixis and verbal politeness in request production in english and spanish

    OpenAIRE

    Díaz Pérez, Francisco Javier

    2006-01-01

    El ensayo del dramaturgo británico constituye una introducción indispensable para el resto de artículos de este volumen, ya que, en todos ellos, se explora alguna de las cuestiones enunciadas por el autor con respecto a los mecanismos de composición y funcionamiento cultural y social actuales. En su reflexión sobre la malograda dramaturga, Sarah Kane, Bond repasa el conjunto de las circunstancias del hecho dramático, lo humano y la imaginación, para dibujar un certero y a la vez controvertido...

  19. Tuberculosis case finding in first-degree relative contacts not living with index tuberculosis cases in Kampala, Uganda

    OpenAIRE

    Chheng P; Nsereko M; Malone LL; Okware B; Zalwango S; Joloba M; Boom WH; Mupere E; Stein CM

    2015-01-01

    Phalkun Chheng,1,2 Mary Nsereko,2 LaShaunda L Malone,2 Brenda Okware,2 Sarah Zalwango,2 Moses Joloba,2,3 W Henry Boom,2 Ezekiel Mupere,1,2,4 Catherine M Stein1,2 On behalf of the Tuberculosis Research Unit 1Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA; 2Uganda-Case Western Reserve University Research Collaboration, 3Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda; 4Department of Pediatric...

  20. Military Engagement and Forward Presence: Down But Not Out as Tools to Shape and Win

    Science.gov (United States)

    2016-01-01

    No. 4, Fall 2012, pp. 23-35. 18. Sarah Kinosian, “Mexico prepping to buy more Black Hawks: settling in for a lengthy fight in drug war ?” The...Enduring Freedom- Philippines Been a Success?” Small Wars Journal, April 5, 2013. 22. Michael Shifter, “Plan Colombia: A Retrospective,” Ameri- cas...ARMY WAR COLLEGE FOR THIS AND OTHER PUBLICATIONS, VISIT US AT http://www.carlisle.army.mil/ Carlisle Barracks, PA and UNITED STATES ARMY WAR COLLEGE

  1. Writing on Multiple Journeys

    OpenAIRE

    Robbins, Sarah; Pullen, Ann Ellis

    2012-01-01

    In their beautifully researched study and critical edition, Nellie Arnott’s Writings on Angola, 1905–1913: Missionary Narratives Linking Africa and America (Parlor Press), authors Sarah Robbins and Ann Ellis Pullen examine in fine detail the historical record of the transnational network of literary work produced by Arnott. Tracing her legacy in the study’s third chapter, “Writing on Multiple Journeys,” the authors argue on behalf of Arnott’s capacity to create authority and celebrity as well...

  2. A renaissance in library metadata? The importance of community collaboration in a digital world

    Directory of Open Access Journals (Sweden)

    Sarah Bull

    2016-07-01

    Full Text Available This article summarizes a presentation given by Sarah Bull as part of the Association of Learned and Professional Society Publishers (ALPSP seminar ‘Setting the Standard’ in November 2015. Representing the library community at the wide-ranging seminar, Sarah was tasked with making the topic of library metadata an engaging and informative one for a largely publisher audience. With help from co-author Amanda Quimby, this article is an attempt to achieve the same aim! It covers the importance of library metadata and standards in the supply chain and also reflects on the role of the community in successful standards development and maintenance. Special emphasis is given to the importance of quality in e-book metadata and the need for publisher and library collaboration to improve discovery, usage and the student experience. The article details the University of Birmingham experience of e-book metadata from a workflow perspective to highlight the complex integration issues which remain between content procurement and discovery.

  3. Pædagogisk improvisation

    DEFF Research Database (Denmark)

    Kristensen, Dorthe Riis; Leegaard, Sarah Palle

    2017-01-01

    Sarah Palle Leegaard og Dorthe Riis Kristensen indleder deres artikel ”Pædagogisk improvisation” med at konstatere, at ”begrebet pædagogisk improvisation er en definition på pædagogens grundlæggende faglighed på højde med det at trække vejret”. Når vi trækker vejret ind, tager vi dét til os, som...... pædagogisk improvisation er udviklet i forbindelse med et forskningsprojekt, hvor Sarah Palle Leegaard og Dorthe Riis Kristensen har fokus på det, de betegner som pædagogens upåagtede faglighed i skoleregi. Hensigten er at udvikle en tydelig fagforskel i henholdsvis lærer- og pædagogprofessionen med henblik...... på at styrke samarbejdet. På baggrund af undersøgelser i praksis i form af bl.a. interviews med lærere og pædagoger, iagttagelser af situationer fra samarbejdet i klasserummet samt oplæg og praktiske øvelser i pædagogisk improvisation (dans) redegør artiklen for, hvordan de deltagende lærere og...

  4. Queensland's proposed surrogacy legislation: an opportunity for national reform.

    Science.gov (United States)

    Johnson, Tammy

    2010-02-01

    Surrogacy has existed since Biblical times when Hagar, the maidservant of the infertile Sarah, acted as a surrogate to bear Sarah and her husband, Abraham, a son. Despite the longevity of the practice of surrogacy, modern society has been reluctant to embrace surrogacy arrangements due to the ethical and sometimes practical debates they spark. This reluctance is evidenced by the general lack of legislative support for surrogacy arrangements in Australia and worldwide. In 2009 it was announced that Queensland will decriminalise altruistic surrogacy. While this decision is a step towards bringing Queensland in line with other Australian jurisdictions, it also has the potential to open up a Pandora's Box of legal and ethical issues. This article provides a snapshot of the anticipated new Queensland surrogacy legislation together with a brief overview of the regulation of surrogacy in all Australian jurisdictions. Recommendations are made as to whether there is a need for further reform of surrogacy regulation in certain Australian jurisdictions and if so, whether the proposed Queensland legislation constitutes an appropriate model on which to base such reform.

  5. Portraiture in the Large Lecture: Storying One Chemistry Professor's Practical Knowledge

    Science.gov (United States)

    Eddleton, Jeannine E.

    Practical knowledge, as defined by Freema Elbaz (1983), is a complex, practically oriented set of understandings which teachers use to actively shape and direct their work. The goal of this study is the construction of a social science portrait that illuminates the practical knowledge of a large lecture professor of general chemistry at a public research university in the southeast. This study continues Elbaz's (1981) work on practical knowledge with the incorporation of a qualitative and intentionally interventionist methodology which "blurs the boundaries of aesthetics and empiricism in an effort to capture the complexity, dynamics, and subtlety of human experience and organizational life," (Lawrence-Lightfoot & Davis, 1997). This collection of interviews, observations, writings, and reflections is designed for an eclectic audience with the intent of initiating conversation on the topic of the large lecture and is a purposeful attempt to link research and practice. Social science portraiture is uniquely suited to this intersection of researcher and researched, the perfect combination of methodology and analysis for a project that is both product and praxis. The following research questions guide the study. • Are aspects of Elbaz's practical knowledge identifiable in the research conversations conducted with a large lecture college professor? • Is practical knowledge identifiable during observations of Patricia's large lecture? Freema Elbaz conducted research conversations with Sarah, a high school classroom and writing resource teacher who conducted much of her teaching work one on one with students. Patricia's practice differs significantly from Sarah's with respect to subject matter and to scale.

  6. Final Report for DOE Grant DE-FG02-03ER25579; Development of High-Order Accurate Interface Tracking Algorithms and Improved Constitutive Models for Problems in Continuum Mechanics with Applications to Jetting

    Energy Technology Data Exchange (ETDEWEB)

    Puckett, Elbridge Gerry [U.C. Davis, Department of Mathematics; Miller, Gregory Hale [.C. Davis, Department of Chemical Engineering

    2012-10-14

    Much of the work conducted under the auspices of DE-FG02-03ER25579 was characterized by an exceptionally close collaboration with researchers at the Lawrence Berkeley National Laboratory (LBNL). For example, Andy Nonaka, one of Professor Miller's graduate students in the Department of Applied Science at U. C. Davis (UCD) wrote his PhD thesis in an area of interest to researchers in the Applied Numerical Algorithms Group (ANAG), which is a part of the National Energy Research Supercomputer Center (NERSC) at LBNL. Dr. Nonaka collaborated closely with these researchers and subsequently published the results of this collaboration jointly with them, one article in a peer reviewed journal article and one paper in the proceedings of a conference. Dr. Nonaka is now a research scientist in the Center for Computational Sciences and Engineering (CCSE), which is also part of the National Energy Research Supercomputer Center (NERSC) at LBNL. This collaboration with researchers at LBNL also included having one of Professor Puckett's graduate students in the Graduate Group in Applied Mathematics (GGAM) at UCD, Sarah Williams, spend the summer working with Dr. Ann Almgren, who is a staff scientist in CCSE. As a result of this visit Sarah decided work on a problem suggested by the head of CCSE, Dr. John Bell, for her PhD thesis. Having finished all of the coursework and examinations required for a PhD, Sarah stayed at LBNL to work on her thesis under the guidance of Dr. Bell. Sarah finished her PhD thesis in June of 2007. Writing a PhD thesis while working at one of the University of California (UC) managed DOE laboratories is long established tradition at UC and Professor Puckett has always encouraged his students to consider doing this. Another one of Professor Puckett's graduate students in the GGAM at UCD, Christopher Algieri, was partially supported with funds from DE-FG02-03ER25579 while he wrote his MS thesis in which he analyzed and extended work originally

  7. Satellite-based climate data records of surface solar radiation from the CM SAF

    Science.gov (United States)

    Trentmann, Jörg; Cremer, Roswitha; Kothe, Steffen; Müller, Richard; Pfeifroth, Uwe

    2017-04-01

    The incoming surface solar radiation has been defined as an essential climate variable by GCOS. Long term monitoring of this part of the earth's energy budget is required to gain insights on the state and variability of the climate system. In addition, climate data sets of surface solar radiation have received increased attention over the recent years as an important source of information for solar energy assessments, for crop modeling, and for the validation of climate and weather models. The EUMETSAT Satellite Application Facility on Climate Monitoring (CM SAF) is deriving climate data records (CDRs) from geostationary and polar-orbiting satellite instruments. Within the CM SAF these CDRs are accompanied by operational data at a short time latency to be used for climate monitoring. All data from the CM SAF is freely available via www.cmsaf.eu. Here we present the regional and the global climate data records of surface solar radiation from the CM SAF. The regional climate data record SARAH (Surface Solar Radiation Dataset - Heliosat, doi: 10.5676/EUM_SAF_CM/SARAH/V002) is based on observations from the series of Meteosat satellites. SARAH provides 30-min, daily- and monthly-averaged data of the effective cloud albedo, the solar irradiance (incl. spectral information), the direct solar radiation (horizontal and normal), and the sunshine duration from 1983 to 2015 for the full view of the Meteosat satellite (i.e, Europe, Africa, parts of South America, and the Atlantic ocean). The data sets are generated with a high spatial resolution of 0.05° allowing for detailed regional studies. The global climate data record CLARA (CM SAF Clouds, Albedo and Radiation dataset from AVHRR data, doi: 10.5676/EUM_SAF_CM/CLARA_AVHRR/V002) is based on observations from the series of AVHRR satellite instruments. CLARA provides daily- and monthly-averaged global data of the solar irradiance (SIS) from 1982 to 2015 with a spatial resolution of 0.25°. In addition to the solar surface

  8. Session: Avian migration and implications for wind power development in the Eastern United States

    Energy Technology Data Exchange (ETDEWEB)

    Mabey, Sarah; Cooper, Brian

    2004-09-01

    This session at the Wind Energy and Birds/Bats workshop consisted of two presentations followed by a discussion/question and answer period. The session was arranged to convey what is known about avian migration, particularly in the eastern US. The first presentation ''Migration Ecology: Issues of Scale and Behavior'' by Sarah Mabey frames the issue of migratory bird interactions with wind energy facilities from an ecological perspective: when, where, and why are migrant bird species vulnerable to wind turbine collision. The second presentation ''Radar Studies of Nocturnal Migration at Wind Sites in the Eastern US'' by Brian Cooper reported on radar studies conducted at wind sites in the eastern US, including Mount Storm, Clipper Wind, and others.

  9. Cognitive systems engineering in health care

    CERN Document Server

    Bisantz, Ann M; Fairbanks, Rollin J

    2014-01-01

    Cognitive Engineering for Better Health Care Systems, Ann M. Bisantz, Rollin J. Fairbanks, and Catherine M. BurnsThe Role of Cognitive Engineering in Improving Clinical Decision Support, Anne Miller and Laura MilitelloTeam Cognitive Work Analysis as an Approach for Understanding Teamwork in Health Care, Catherine M. BurnsCognitive Engineering Design of an Emergency Department Information System, Theresa K. Guarrera, Nicolette M. McGeorge, Lindsey N. Clark, David T. LaVergne, Zachary A. Hettinger, Rollin J. Fairbanks, and Ann M. BisantzDisplays for Health Care Teams: A Conceptual Framework and Design Methodology, Avi ParushInformation Modeling for Cognitive Work in a Health Care System, Priyadarshini R. PennathurSupport for ICU Clinician Cognitive Work through CSE, Christopher Nemeth, Shilo Anders, Jeffrey Brown, Anna Grome, Beth Crandall, and Jeremy PamplinMatching Cognitive Aids and the "Real Work" of Health Care in Support of Surgical Microsystem Teamwork, Sarah Henrickson Parker and Shawna J. PerryEngageme...

  10. Multifocal choroiditis following simultaneous hepatitis A, typhoid, and yellow fever vaccination

    Directory of Open Access Journals (Sweden)

    Escott S

    2013-02-01

    Full Text Available Sarah Escott, Ahmad B Tarabishy, Frederick H DavidorfHavener Eye Institute, The Ohio State University, Columbus, OH, USAAbstract: The paper describes the first reported case of multifocal choroiditis following simultaneous hepatitis-A, typhoid, and yellow fever vaccinations. A 33-year-old male developed sudden onset of flashing lights and floaters in his right eye 3 weeks following hepatitis A, typhoid, and yellow fever vaccinations. Fundus examination and angiography confirmed the presence of multiple peripheral chorioretinal lesions. These lesions demonstrated characteristic morphologic changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis. Vaccine-induced intraocular inflammation has been described infrequently. We demonstrate the first case of self-resolving multifocal choroiditis following simultaneous administration of hepatitis A, yellow fever, and typhoid immunizations.Keywords: multifocal choroiditis, vaccination, hepatitis A, typhoid, yellow fever

  11. De la estética de la recepción a la animación a la lectura: consideraciones teóricas para una propuesta de animación de la lectura literaria en espacios no convencionales

    OpenAIRE

    Higuera Guarín, Gladys Yaneth

    2016-01-01

    El presente artículo propone explorar el modo en que la estética de la recepción se consolida como la base para entender la importancia de la promoción de lectura en comunidades vulnerables. Esta reflexión constituye la base teórica para la implementación de un proyecto de animación de lectura con los internos de la cárcel El Olivo de Santa Rosa de Viterbo, en el cual se emplean las fichas de animación de Beatriz Helena Robledo y las categorías de análisis literario de Sarah Hirschman. The...

  12. Editorial, Volume 7, Issue 2

    Directory of Open Access Journals (Sweden)

    Kristy L Archuleta

    2016-12-01

    Full Text Available This issue features four articles, two profiles, and one book review. Each article adds a new contribution to the field of financial therapy. First, Dr. Asebedo applies a conflict resolution framework to money arguments. Next, Drs. Rea, Zuiker, and Mendenhall explore financial management practices among emerging adult couples. In the third paper, Drs. Ann Woodyard and Cliff Robb help to add further description of financial satisfaction. Then, Dr. Russell James offers a unique theoretical analysis of mortality salience and financial decisions. This issue also features a practitioner profile of Beth Crittenden and a scholar profile of Sarah Asebedo. Finally, we conclude with a review by Neal VanZutphen about a book entitled, The Seven Principles for Making Marriage Work.

  13. 以適讀性公式挑選英文讀本之探究 How to Use Readability Formulas to Access and Select English Reading Materials

    Directory of Open Access Journals (Sweden)

    Hai-Hon Chen

    2012-12-01

    Full Text Available 本研究旨在說明常用的適讀性公式。以三本英文讀本The empty pot(670字)、Smoky night(1,267字)、和Sarah, plain and tall(3,158字)為研究對象,以Microsoft Word文書處理軟體的可讀性公式、網路免費適讀工具的適讀公式、以及手算,進行讀物適讀年級程度的計算;其次,比較同一讀本在不同的適讀軟體公式或手算所得的結果是否相同?研究結果指出: 1. 三本讀物The empty pot字數最少、適合美國五年級程度閱讀,Sarah, plain and tall字數最多、適合美國三、四年級閱讀程度,Smoky night適合美國三年級程度。 2. Microsoft Word文書處理的可讀性公式統計,可取得文本全文的適讀分數及年級程度,簡易方便使用。 3. 適讀性公式會依公式採用分析比較的因素不同,結果稍有差異,但每本書的難度排列順序或適讀年級的順序是相同的。 4. 適讀性公式的決定因素相同,不論是手算的Fry圖或使用電腦工具的Flesch-Kincaid,所得的年級程度相同。文中並提出臺灣教師、圖書教師或館員應用適讀性公式為臺灣學生選擇英語讀物的建議。The purpose of this study was to describe the most common readability formulas. Three children’s books, The empty pot (670 words, Smoky night (1,267 words, and Sarah, plain and tall (3,158 words were used as the subjects to calculate the numerical or grade-level score. The study also focused on comparing readability formulas that were calculated using different methods: with a tool embedded in a Microsoft Word processing program, with Free Text Readability Consensus Calculator tools found on the web, and by hand. Results were presented as follows: 1. The empty pot that was the least words got a fifth-grade level, Sarah, plain and tall that was the most words got a third-fourth grade level, Smoky night a third grade level. 2. Readability formula embedded in a Microsoft

  14. Trends In Academic Content for Mobile Devices [video

    Directory of Open Access Journals (Sweden)

    Dan D'Agostino

    2012-06-01

    Full Text Available This presentation by Sarah Forbes and Dan D'Agostino was given at the Ontario Library Association's Super Conference in Toronto, Ontario, on February 3, 2012. Session Abstract from the Super Conference Program: As ownership of mobile devices continues to proliferate, libraries are finding it difficult to provide academic content that works well in the mobile world. Discover how various e-book and e-journal formats can be made to work with mobile devices of all kinds, and will explore the next generation of digital content designed for mobile devices – new formats that may re-invent how information is used by readers. Partnership would like to thank the authors and the Ontario Library Association for their generous permission to publish an Open Access version of this conference session. This is one of several Super Conference 2012 video presentations available for purchase from Super Conference: the Virtual Experience - http://ola.scholarlab.ca/.

  15. MRI findings in the painful hemiplegic shoulder

    International Nuclear Information System (INIS)

    Tavora, D.G.F.; Gama, R.L.; Bomfim, R.C.; Nakayama, M.; Silva, C.E.P.

    2010-01-01

    Aim: To evaluate the magnetic resonance imaging (MRI) findings in painful hemiplegic shoulder (PHS) in hemiplegic post-stroke patients. Materials and methods: Patients with hemiplegia following their first cerebrovascular accident who were admitted to the Sarah Network of Hospitals for Rehabilitation were studied. Forty-five patients with pain in the hemiplegic shoulder and 23 post-stroke patients without shoulder pain were investigated. MRI and radiographic findings of the hemiplegic and contralateral asymptomatic shoulders were evaluated. Results: Some MRI findings were more frequent in PHS group, including synovial capsule thickening, synovial capsule enhancement, and enhancement in the rotator cuff interval. Conclusions: Adhesive capsulitis was found to be a possible cause of PHS.

  16. MRI findings in the painful hemiplegic shoulder

    Energy Technology Data Exchange (ETDEWEB)

    Tavora, D.G.F., E-mail: danielgurgel@sarah.b [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Gama, R.L.; Bomfim, R.C. [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Nakayama, M. [Department of Radiology, Federal University of Grande Dourados, Dourados (Brazil); Silva, C.E.P. [Department of Statistics, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil)

    2010-10-15

    Aim: To evaluate the magnetic resonance imaging (MRI) findings in painful hemiplegic shoulder (PHS) in hemiplegic post-stroke patients. Materials and methods: Patients with hemiplegia following their first cerebrovascular accident who were admitted to the Sarah Network of Hospitals for Rehabilitation were studied. Forty-five patients with pain in the hemiplegic shoulder and 23 post-stroke patients without shoulder pain were investigated. MRI and radiographic findings of the hemiplegic and contralateral asymptomatic shoulders were evaluated. Results: Some MRI findings were more frequent in PHS group, including synovial capsule thickening, synovial capsule enhancement, and enhancement in the rotator cuff interval. Conclusions: Adhesive capsulitis was found to be a possible cause of PHS.

  17. Throne of Glass, Celaena Sardothien et la violence au féminin

    Directory of Open Access Journals (Sweden)

    Fanie Demeule

    2017-05-01

    Full Text Available En analysant le cas de l’héroïne de la série de fantasy jeunesse Throne of Glass de Sarah J. Maas, cet article désire réfléchir sur la normativité des représentations de la violence physique chez un personnage littéraire de sexe féminin. Pour ce faire, nous examinerons dans un premier temps les stratégies de négociation de la violence du personnage de Celaena Sardothien à travers le dispositif textuel, puis nous observerons la polémique entourant sa réception au sein du lectorat.

  18. The African State and the role and nature of non-state sources of security in the Democratic Republic of Congo and South Africa

    DEFF Research Database (Denmark)

    Mandrup, Thomas

    2012-01-01

    use of violence as being the domain of the modern state, which as a natural consequence, delegitimises non-state providers of security. Legitimacy is, therefore, tied to the formal state. Th e international debate concerning the role of PMSCs has been split primarily into two segments. One argues...... to control confl icts has led to low-intensity confl icts (LIC), which can be witnessed, for instance, in Uganda, the Democratic Republic of Congo, Colombia and Sri Lanka (O’Brien, 1998, p. 80). Since the end of the Cold War it has been common for weak state rulers with formal state legitimacy...... security contractors have led, both historically and at the present day, to fi erce academic and public debate. As Sarah Percy argues, the anti-mercenary discourse has two basic elements. One focuses on the fact that mercenaries use force outside what is considered to be legitimate, authoritative control...

  19. Privatisation of security:

    DEFF Research Database (Denmark)

    use of violence as being the domain of the modern state, which as a natural consequence, delegitimises non-state providers of security. Legitimacy is, therefore, tied to the formal state. Th e international debate concerning the role of PMSCs has been split primarily into two segments. One argues...... to control confl icts has led to low-intensity confl icts (LIC), which can be witnessed, for instance, in Uganda, the Democratic Republic of Congo, Colombia and Sri Lanka (O’Brien, 1998, p. 80). Since the end of the Cold War it has been common for weak state rulers with formal state legitimacy...... security contractors have led, both historically and at the present day, to fi erce academic and public debate. As Sarah Percy argues, the anti-mercenary discourse has two basic elements. One focuses on the fact that mercenaries use force outside what is considered to be legitimate, authoritative control...

  20. Taus and the Trigger for Discovery at ATLAS

    International Nuclear Information System (INIS)

    Demers, Sarah

    2017-01-01

    This five year grant allowed Yale Professor Sarah Demers and her students and postdocs to contribute to the ATLAS Experiment at CERN's Large Hadron Collider. We worked on a particular mode of the Higgs Boson decay, contributing to the discovery of this particle as well as measuring the particle's properties. We also performed a 'first of its kind' measurement at a hadron collider in the measurement of tau polarization, which increased the sensitivity of ATLAS in a number of exciting ways, both for making measurements of known particles and for hunting for new ones. We also contributed to the tau trigger - the real-time selection that chooses data that includes the signature of the tau lepton. Four PhD students in the Yale Physics Department received their PhDs during the term of this grant, with at least partial support from the grant.

  1. Systematic review of the association between Alzheimer’s disease and chronic glaucoma

    Directory of Open Access Journals (Sweden)

    Janssen SF

    2015-05-01

    Full Text Available Sarah F Janssen,1 Nomdo M Jansonius,2 Femke Bouwman,3 Frank D Verbraak,1,4 Arthur A Bergen51Department of Ophthalmology, VU Medical Center, Amsterdam; 2Department of Ophthalmology, University of Groningen, University Medical Center Groningen, Groningen; 3Alzheimer Center, VU Medical Center, 4Department of Ophthalmology, 5Department of Clinical Genetics, Academic Medical Center, Amsterdam, the NetherlandsWe read with great interest the paper by Tsilis et al entitled "Systematic review of the association between Alzheimer’s disease and chronic glaucoma" published recently in this journal.1 The potential overlap in the pathobiological background of Alzheimer’s disease (AD and primary open angle glaucoma (POAG is currently a topic of intense discussion and could provide further insight into both of these complex diseases.View original paper by Tsilis et al.

  2. ‘When the Reservoir Comes’: Drowned Villages, Community and Nostalgia in Contemporary British Fiction

    Directory of Open Access Journals (Sweden)

    Eileen Pollard

    2017-12-01

    Full Text Available A ‘drowned’ or flooded village describes the destruction of a settlement or community to make way for a reservoir; as a practice, it most commonly occurred in Britain during the late nineteenth and early twentieth centuries when the need for fresh water in growing industrial cities was at its height. This essay will explore three different representations of the ‘drowned village’ in contemporary British fiction. Reginald Hill’s On Beulah Height (1992, Hilary Mantel’s short story ‘The Clean Slate’ (2001 and Sarah Hall’s Haweswater (2002 will all be considered in terms of how the drowned village is presented and described, and what this representation suggests about the ways nostalgia, ritual and ruin impact upon notions of community and place.

  3. Neurose traumática, neurose de transferência: um relato autobiográfico do holocausto

    OpenAIRE

    Gustavo Adolfo Ramos Mello Neto

    2012-01-01

    Trata-se de tomar em conta neuroses que se desenvolvem a partir de um trauma explícito, ocorrido na realidade material, mas que se apresentam com algumas características de neuroses de transferência. Expõe-se, então, algo da descrição clássica da neurose traumática e, em seguida, um relato autobiográfico da escritora franco-judia Sarah Kofman, que passou sua infância na França durante a Segunda Guerra Mundial, teve seu pai morto em Auschwitz e foi obrigada a viver escondida durante esse perío...

  4. Women Artists: The Linda Nochlin Reader 

    OpenAIRE

    Allain Bonilla, Marie-Laure

    2016-01-01

    De Linda Nochlin, on connaît essentiellement l’essai explosif « Why Have There Been No Great Female Artists? » (1971), référence incontournable de l’histoire de l’art féministe, et les écrits sur la représentation des femmes par les artistes masculins au XIXe siècle. L’originalité de cette anthologie est qu’elle met en avant les écrits de Linda Nochlin sur les femmes artistes, de Berthe Morisot à Sarah Lucas, à travers une sélection de trente essais rédigés depuis 1971 et classés par décennie...

  5. Inchbald’S Kotzebue: The Wise Man of the East (1799 and Social Assemblage Theory

    Directory of Open Access Journals (Sweden)

    Worrall David

    2014-02-01

    Full Text Available This article argues that Lord Mansfield's judgement in favour of the actor Charles Macklin in 1775 wrought a profound change on noisy and disruptive theatre auditoriums. Mansfield ruled that persons returning to theatres to repeatedly disrupt performances were guilty of conspiracy and performers' lost earning were assessed as felonies in English common law. Those found guilty might have substantial damages awarded against them and might be liable for a prison sentence. The paper traces that Garrick's Drury Lane was repeatedly disrupted but with no action being taken, even though ringleaders had been identified. Macklin's case, arising from his engagement at Covent Garden, suppressed repeatedly rowdy evenings. The paper suggests that Sarah Siddons's rise at Drury Lane from 1782 onwards was linked to these changes in the legal environment for stage performers.

  6. WRONGFUL TRADING: COMPARATIVE APPROACH (ENGLAND AND WALES, RUSSIA AND THE USA

    Directory of Open Access Journals (Sweden)

    D. Konstantinov

    2015-01-01

    Full Text Available This paper is designed to discover legal rules addressing insolvency trading in three jurisdictions: England and Wales, Russia and the USA. Originally it was a master’s dissertation written under supervision of Ms. Sarah Paterson, who was extremely helpful and patient. The key jurisdiction for the research is England and Wales, whose wrongful trading provision apparently was the very first insolvency regulation in the field. Here, we will give particular attention to the factual circumstances of insolvency trading and research how the concept of wrongful trading addresses them. The next question will be how the American concept of deepening insolvency and the Russian concept of subsidiary liability are comparable with wrongful trading. Later, we will focus on the functions that should be performed by the regulations. Also, the effectiveness of wrongful trading and similar overseas provisions will be examined. Finally, this paper attempts to find obstacles to the wide application of wrongful trading provision.

  7. More features, greater connectivity.

    Science.gov (United States)

    Hunt, Sarah

    2015-09-01

    Changes in our political infrastructure, the continuing frailties of our economy, and a stark growth in population, have greatly impacted upon the perceived stability of the NHS. Healthcare teams have had to adapt to these changes, and so too have the technologies upon which they rely to deliver first-class patient care. Here Sarah Hunt, marketing co-ordinator at Aid Call, assesses how the changing healthcare environment has affected one of its fundamental technologies - the nurse call system, argues the case for wireless such systems in terms of what the company claims is greater adaptability to changing needs, and considers the ever-wider range of features and functions available from today's nurse call equipment, particularly via connectivity with both mobile devices, and ancillaries ranging from enuresis sensors to staff attack alert 'badges'.

  8. Brilliant! New Art from London, Walker Art Center, 1995–96

    Directory of Open Access Journals (Sweden)

    Richard Flood

    2016-07-01

    Full Text Available There can be little doubt that the accepted origins of the Young British Artists (YBAs began with Freeze, the exhibition organized by Damian Hirst in 1988. It was packed with graduates of Goldsmiths College where the artist and educator Michael Craig-Martin had recently revamped the curriculum to allow students to choose from a buffet of courses, rather than using the prix fixe menu. Hirst turned out to be a natural entrepreneur and guided his fellow Goldsmiths’ graduates into the public eye well before the traditional art world machinations would have allowed. After Freeze came Modern Medicine, spearheaded by Hirst, Carl Freedman, and Billee Sellman, and East Country Yard Show, devised by Sarah Lucas and Henry Bond, both in 1990. A year later, the Serpentine Gallery endorsed what was beginning to feel something like a movement in its Broken English exhibition, overseen by Hirst.

  9. Le travesti dans le théâtre du xixe siècle : une distribution à contre-genre ?

    OpenAIRE

    Khoury, Camille

    2018-01-01

    Quelques-unes des actrices les plus célèbres du xixe siècle ont laissé à la postérité le souvenir de leurs rôles travestis. C’est notamment le cas de Virginie Déjazet – au point que le déjazet est rapidement devenu synonyme de rôle travesti – ou encore de Sarah Bernhardt. Le travesti est alors un spectacle commun sur les scènes académiques françaises – tandis que certains rôles sont écrits pour être joués en travesti, de grandes actrices s’emparent de rôles masculins pour confronter leur géni...

  10. The hunting season’s over

    CERN Document Server

    2014-01-01

    Hundreds of Internet users from across the globe have been scouring the Computer Centre for LEGO figurines in recent weeks (see here). The time has come to announce the results…   We’ve received nearly 5,000 screen-shots, the precious trophies gleaned from hours of virtual scavenging through the CERN Computing Centre, and we’re pleased to see our hunt raised so much interest. Unfortunately, rules being rules, we have to choose the two winners by drawing lots, so prizes will be winging their way to… Sarah Charley (CERN) Stefan Hayes We kindly thank everyone who took part in the hunt with so much gusto and hope you all had as much fun as we did! You can discover all the figurines here: http://lego-scavenger-hunt.web.cern.ch/ The CERN Bulletin team

  11. Russian science trapped in web of rapid change

    International Nuclear Information System (INIS)

    Josephson, P.R.

    1995-01-01

    During the Cold War, Soviet physicists were revered for their contribution to the country's prestige, economic growth, and national security, says Paul Josephson, a professor in the Department of Science, Technology, and Society at Sarah Lawrence College in Bronxville, New York. But the lavish support the Russian physics establishment once received is gone. In fact, the dissolution of the Soviet regime and deepening economic and political crisis have left scientists struggling to maintain their programs and keep institutes open. Internal crisis and the internationalization of science and technology have led to a drain of top Russian scientists in many fields, particularly in mathematics and theoretical physics. The West has responded to these concerns by giving financial aid and sponsoring initiatives designed to keep former Soviet scientists employed either at home or in the United States or Europe. However, the ultimate health of Russian science will depend on internal government reforms and public support, concludes Josephson

  12. TEDGlobal>Geneva

    CERN Document Server

    Claudia Marcelloni

    2015-01-01

    On Tuesday 8 December, a TEDGlobal Conference took place at the Bâtiment des Forces Motrices (BFM) in downtown Geneva.   Charlotte Lindberg Warakaulle, Director for International Relations at CERN, speaking at the workshop for TEDx organisers held at CERN (Image: Laetitia Gessler)  Curated by Bruno Giussani, the TED European Director, it was the first official TED event to take place in Switzerland. Under the theme “Critical Junctures” the program, which was unknown to the audience beforehand, featured two sessions and more than a dozen speakers. Among them were voices from local residents whose work has worldwide impact, such as the UN High Commissioner for Refugees, Antonio Guterres; Swiss neurosurgeon Jocelyne Bloch; Head of the Biorobotics Laboratory at EPFL, Auke Ijspeert; Founder of Apelab, Emilie Joly; and National Geographic explorer, Sarah Marquis. CERN was represented by a particle physicist from the LHCb collab...

  13. Primordial Spirituality

    Directory of Open Access Journals (Sweden)

    Kees Waaijman

    2010-11-01

    Full Text Available This article explores the primordial spirituality of the Bible, as expressed in names, narratives and prayers. It looks at the nomadic families of Abraham and Sarah, Isaac and Rebecca, Jacob, Lea and Rachel, moving around from Mesopotamia via Canaan into Egypt and vice versa (see Gn 11:31–32; 12:4–5; 27:43; 28:10; 29:4; Gn 24 and 29–31. It analyses their experiences, covering the span between birth and death and listens to their parental concerns about education as survival. It also follows their journeys along the margins of the deserts. It shares their community life as it takes shape in mutual solidarity, mercy and compassion.

  14. Award ceremony for the "Crèche and School" competition

    CERN Multimedia

    Staff Association

    2018-01-01

    Whenever there is a competition, there are obviously participants – and especially winners! The awards ceremony for the competition to find a new name for the CERN Staff Association's Crèche and School took place on 15 May. During the ceremony, jointly led by Céline Grobon (President of the Crèche and School Steering Committee), Carole Dargagnon (Headmistress of the Crèche and School) and Jean-Baptiste Zenner (Staff Association delegate), the proposals selected by the jury were rewarded. The first place went to Marie-Luz Cavagna for her proposal "Le jardin des petits chercheurs", and the second place to Sarah Palluel for her proposal "Le Jardin des Zélectrons". Finally, Aude Mourey and Sandra Fleury tied for third place with their respective proposals "Les petits atomes" and "La crèche des particules". Can we find the winning name of the competition among...

  15. Generic calculation of two-body partial decay widths at the full one-loop level

    Science.gov (United States)

    Goodsell, Mark D.; Liebler, Stefan; Staub, Florian

    2017-11-01

    We describe a fully generic implementation of two-body partial decay widths at the full one-loop level in the SARAH and SPheno framework compatible with most supported models. It incorporates fermionic decays to a fermion and a scalar or a gauge boson as well as scalar decays into two fermions, two gauge bosons, two scalars or a scalar and a gauge boson. We present the relevant generic expressions for virtual and real corrections. Whereas wave-function corrections are determined from on-shell conditions, the parameters of the underlying model are by default renormalised in a \\overline{ {DR}} (or \\overline{ {MS}}) scheme. However, the user can also define model-specific counter-terms. As an example we discuss the renormalisation of the electric charge in the Thomson limit for top-quark decays in the standard model. One-loop-induced decays are also supported. The framework additionally allows the addition of mass and mixing corrections induced at higher orders for the involved external states. We explain our procedure to cancel infrared divergences for such cases, which is achieved through an infrared counter-term taking into account corrected Goldstone boson vertices. We compare our results for sfermion, gluino and Higgs decays in the minimal supersymmetric standard model (MSSM) against the public codes SFOLD, FVSFOLD and HFOLD and explain observed differences. Radiatively induced gluino and neutralino decays are compared against the original implementation in SPheno in the MSSM. We exactly reproduce the results of the code CNNDecays for decays of neutralinos and charginos in R-parity violating models. The new version SARAH 4.11.0 by default includes the calculation of two-body decay widths at the full one-loop level. Current limitations for certain model classes are described.

  16. Generic calculation of two-body partial decay widths at the full one-loop level

    Energy Technology Data Exchange (ETDEWEB)

    Goodsell, Mark D. [UPMC Univ. Paris 06 (France); Centre National de la Recherche Scientifique (CNRS), 75 - Paris (France); Sorbonne Univ., Paris (France); Liebler, Stefan [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Staub, Florian [Karlsruhe Institute for Technology, Karlsruhe (Germany). Inst. for Theoretical Physics; Karlsruhe Institute for Technology, Eggenstein-Leopoldshafen (Germany). Inst. for Nuclear Physics

    2017-04-15

    We describe a fully generic implementation of two-body partial decay widths at the full one-loop level in the SARAH and SPheno framework compatible with most supported models. It incorporates fermionic decays to a fermion and a scalar or a gauge boson as well as scalar decays into two fermions, two gauge bosons, two scalars or a scalar and a gauge boson. We present the relevant generic expressions for virtual and real corrections. Whereas wavefunction corrections are determined from on-shell conditions, the parameters of the underlying model are by default renormalised in a DR (or MS) scheme. However, the user can also define model-specific counter-terms. As an example we discuss the renormalisation of the electric charge in the Thomson limit for top-quark decays in the standard model. One-loop induced decays are also supported. The framework additionally allows the addition of mass and mixing corrections induced at higher orders for the involved external states. We explain our procedure to cancel infra-red divergences for such cases, which is achieved through an infra-red counter-term taking into account corrected Goldstone boson vertices. We compare our results for sfermion, gluino and Higgs decays in the minimal supersymmetric standard model (MSSM) against the public codes SFOLD, FVSFOLD and HFOLD and explain observed differences. Radiative induced gluino and neutralino decays are compared against the original implementation in SPheno in the MSSM. We exactly reproduce the results of the code CNNDecays for decays of neutralinos and charginos in R-parity violating models. The new version SARAH 4.11.0 by default includes the calculation of two-body decay widths at the full one-loop level. Current limitations for certain model classes are described.

  17. A new CM SAF Solar Surface Radiation Climate Data Set derived from Meteosat Satellite Observations

    Science.gov (United States)

    Trentmann, J.; Mueller, R. W.; Pfeifroth, U.; Träger-Chatterjee, C.; Cremer, R.

    2014-12-01

    The incoming surface solar radiation has been defined as an essential climate variable by GCOS. It is mandatory to monitor this part of the earth's energy balance, and thus gain insights on the state and variability of the climate system. In addition, data sets of the surface solar radiation have received increased attention over the recent years as an important source of information for the planning of solar energy applications. The EUMETSAT Satellite Application Facility on Climate Monitoring (CM SAF) is deriving surface solar radiation from geostationary and polar-orbiting satellite instruments. While CM SAF is focusing on the generation of high-quality long-term climate data records, also operationally data is provided in short time latency within 8 weeks. Here we present SARAH (Solar Surface Radiation Dataset - Heliosat), i.e. the new CM SAF Solar Surface Radiation data set based on Meteosat satellite observations. SARAH provides instantaneous, daily- and monthly-averaged data of the effective cloud albedo (CAL), the direct normalized solar radiation (DNI) and the solar irradiance (SIS) from 1983 to 2013 for the full view of the Meteosat satellite (i.e, Europe, Africa, parts of South America, and the Atlantic ocean). The data sets are generated with a high spatial resolution of 0.05 deg allowing for detailed regional studies, and are available in netcdf-format at no cost without restrictions at www.cmsaf.eu. We provide an overview of the data sets, including a validation against reference measurements from the BSRN and GEBA surface station networks.

  18. Generic calculation of two-body partial decay widths at the full one-loop level

    Energy Technology Data Exchange (ETDEWEB)

    Goodsell, Mark D. [Sorbonne Universites, UPMC Univ Paris 06, UMR 7589, LPTHE, Paris (France); CNRS, UMR 7589, LPTHE, Paris (France); Liebler, Stefan [DESY, Hamburg (Germany); Staub, Florian [Karlsruhe Institute of Technology, Institute for Theoretical Physics (ITP), Karlsruhe (Germany); Karlsruhe Institute of Technology, Institute for Nuclear Physics (IKP), Eggenstein-Leopoldshafen (Germany)

    2017-11-15

    We describe a fully generic implementation of two-body partial decay widths at the full one-loop level in the SARAH and SPheno framework compatible with most supported models. It incorporates fermionic decays to a fermion and a scalar or a gauge boson as well as scalar decays into two fermions, two gauge bosons, two scalars or a scalar and a gauge boson. We present the relevant generic expressions for virtual and real corrections. Whereas wave-function corrections are determined from on-shell conditions, the parameters of the underlying model are by default renormalised in a DR (or MS) scheme. However, the user can also define model-specific counter-terms. As an example we discuss the renormalisation of the electric charge in the Thomson limit for top-quark decays in the standard model. One-loop-induced decays are also supported. The framework additionally allows the addition of mass and mixing corrections induced at higher orders for the involved external states. We explain our procedure to cancel infrared divergences for such cases, which is achieved through an infrared counter-term taking into account corrected Goldstone boson vertices. We compare our results for sfermion, gluino and Higgs decays in the minimal supersymmetric standard model (MSSM) against the public codes SFOLD, FVSFOLD and HFOLD and explain observed differences. Radiatively induced gluino and neutralino decays are compared against the original implementation in SPheno in the MSSM. We exactly reproduce the results of the code CNNDecays for decays of neutralinos and charginos in R-parity violating models. The new version SARAH 4.11.0 by default includes the calculation of two-body decay widths at the full one-loop level. Current limitations for certain model classes are described. (orig.)

  19. The Promise and Pitfalls of Using Crowdsourcing in Research Prioritization for Back Pain: Cross-Sectional Surveys.

    Science.gov (United States)

    Bartek, Matthew A; Truitt, Anjali R; Widmer-Rodriguez, Sierra; Tuia, Jordan; Bauer, Zoya A; Comstock, Bryan A; Edwards, Todd C; Lawrence, Sarah O; Monsell, Sarah E; Patrick, Donald L; Jarvik, Jeffrey G; Lavallee, Danielle C

    2017-10-06

    The involvement of patients in research better aligns evidence generation to the gaps that patients themselves face when making decisions about health care. However, obtaining patients' perspectives is challenging. Amazon's Mechanical Turk (MTurk) has gained popularity over the past decade as a crowdsourcing platform to reach large numbers of individuals to perform tasks for a small reward for the respondent, at small cost to the investigator. The appropriateness of such crowdsourcing methods in medical research has yet to be clarified. The goals of this study were to (1) understand how those on MTurk who screen positive for back pain prioritize research topics compared with those who screen negative for back pain, and (2) determine the qualitative differences in open-ended comments between groups. We conducted cross-sectional surveys on MTurk to assess participants' back pain and allow them to prioritize research topics. We paid respondents US $0.10 to complete the 24-point Roland Morris Disability Questionnaire (RMDQ) to categorize participants as those "with back pain" and those "without back pain," then offered both those with (RMDQ score ≥7) and those without back pain (RMDQ Crowdsourcing platforms such as MTurk support efforts to efficiently reach large groups of individuals to obtain input on research activities. In the context of back pain, a prevalent and easily understood condition, the rank list of those with back pain was highly correlated with that of those without back pain. However, subtle differences in the content and quality of free-text comments suggest supplemental efforts may be needed to augment the reach of crowdsourcing in obtaining perspectives from patients, especially from specific populations. ©Matthew A Bartek, Anjali R Truitt, Sierra Widmer-Rodriguez, Jordan Tuia, Zoya A Bauer, Bryan A Comstock, Todd C Edwards, Sarah O Lawrence, Sarah E Monsell, Donald L Patrick, Jeffrey G Jarvik, Danielle C Lavallee. Originally published in the

  20. Dilemas éticos da vida humana: a trajetória hospitalar de crianças portadoras de paralisia cerebral grave The ethical dilemmas of human life: the hospital history of children with serious cerebral palsy

    Directory of Open Access Journals (Sweden)

    Debora Diniz

    1996-09-01

    Full Text Available O artigo é um estudo antropológico que aborda os pressupostos éticos do tratamento médico ministrado em crianças portadoras de paralisia cerebral grave. A pesquisa foi realizada a partir de um trabalho etnográfico de oito meses, com pacientes em tratamento no Centro de Paralisia Cerebral do Hospital Sarah, Salvador. A observação da terapêutica ministrada a estas crianças, que apresentam pouquíssimas mudanças do quadro clínico, levou ao questionamento já bastante sugerido em discussões relativas à deontologia médica: Qual o objetivo do tratamento médico empregado nestas crianças? Na verdade, os resultados desta pesquisa indicaram a existência de explicações sócio-humanistas que estariam além da explicação médico-científica oficial, a qual resumiria a terapêutica a um fisicalismo corporal.This study deals with the ethical premises of medical treatment for children with serious cerebral palsy. Eight months of ethnographic research were carried out with patients at the Cerebral Palsy Center in the Sarah Hospital in Salvador, Bahia, Brazil. Observation of treatment for these children, who displayed limited clinical change, led to the following question, as suggested by discussions from medical deontology: What is the purpose of medical treatment for children with serious cerebral palsy? The results of our research point to social and humanist explanations going beyond the official medical scientific explanation, which limits treatment to corporal mechanicism.

  1. Generic calculation of two-body partial decay widths at the full one-loop level

    International Nuclear Information System (INIS)

    Goodsell, Mark D.; Liebler, Stefan; Staub, Florian; Karlsruhe Institute for Technology, Eggenstein-Leopoldshafen

    2017-04-01

    We describe a fully generic implementation of two-body partial decay widths at the full one-loop level in the SARAH and SPheno framework compatible with most supported models. It incorporates fermionic decays to a fermion and a scalar or a gauge boson as well as scalar decays into two fermions, two gauge bosons, two scalars or a scalar and a gauge boson. We present the relevant generic expressions for virtual and real corrections. Whereas wavefunction corrections are determined from on-shell conditions, the parameters of the underlying model are by default renormalised in a DR (or MS) scheme. However, the user can also define model-specific counter-terms. As an example we discuss the renormalisation of the electric charge in the Thomson limit for top-quark decays in the standard model. One-loop induced decays are also supported. The framework additionally allows the addition of mass and mixing corrections induced at higher orders for the involved external states. We explain our procedure to cancel infra-red divergences for such cases, which is achieved through an infra-red counter-term taking into account corrected Goldstone boson vertices. We compare our results for sfermion, gluino and Higgs decays in the minimal supersymmetric standard model (MSSM) against the public codes SFOLD, FVSFOLD and HFOLD and explain observed differences. Radiative induced gluino and neutralino decays are compared against the original implementation in SPheno in the MSSM. We exactly reproduce the results of the code CNNDecays for decays of neutralinos and charginos in R-parity violating models. The new version SARAH 4.11.0 by default includes the calculation of two-body decay widths at the full one-loop level. Current limitations for certain model classes are described.

  2. Introduction to special issue on 'Cosmology and Time' for SHPMP

    Science.gov (United States)

    Grosholz, Emily

    2015-11-01

    This collection of essays stems from the Workshop on Cosmology and Time held at the Pennsylvania State University on April 16-17, 2013, with support from the Department of Philosophy, the Schreyer Honors College, and the Center for Fundamental Theory/Institute for Gravitation and the Cosmos. My thanks to Shannon Sullivan and Susan Welch, Arun Upneja and Christian Brady, and Abhay Ashtekar, Murat Gunaydin and Randi Neshteruk. I'd also like to acknowledge helpful counsel from Gordon Fleming (Professor of Physics Emeritus, Penn State), who has been generous with his time and expertise, and John Norton (Director, Center for History and Philosophy of Science, University of Pittsburgh), who not only contributed to the workshop but also introduced me to the work of two of his graduate students. The original intention of the workshop was to pair younger scholars with older, more established scholars; during the workshop, we listened to exchanges between Bryan Roberts and Abhay Ashtekar, William Nelson and Sarah Shandera, Thomas Pashby and Gordon Fleming, David Sloan and Kurt Gibble, Elie During and myself, and Alexis de Saint-Ours and John Norton. Though some of these exchanges did not persist through the creation of this collection of essays, those that did were further developed in useful ways. I also wanted to bring philosophers and scientists together, as well as colleagues from Europe and North America. The latter intention was strengthened by the later addition of responses or essays by Jeremy Butterfield, Julian Barbour, Klaus Mainzer, and Lee Smolin, to complement the 'overview' essays by Abhay Ashtekar and John Norton that begin and end the second part. Though the thoughtful and stimulating essays and responses by William Nelson, Sarah Shandera, Kurt Gibble, Elie During and Klaus Mainzer did not survive the process of assembling this special issue, because they were too technical or did not fit in structurally or could not be revised in time, their contributions

  3. IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans

    Science.gov (United States)

    Blair, Aaron; Vineis, Paolo; Ahrens, Wolfgang; Andersen, Aage; Anto, Josep M.; Armstrong, Bruce K.; Baccarelli, Andrea A.; Beland, Frederick A.; Berrington, Amy; Bertazzi, Pier Alberto; Birnbaum, Linda S.; Brownson, Ross C.; Bucher, John R.; Cantor, Kenneth P.; Cardis, Elisabeth; Cherrie, John W.; Christiani, David C.; Cocco, Pierluigi; Coggon, David; Comba, Pietro; Demers, Paul A.; Dement, John M.; Douwes, Jeroen; Eisen, Ellen A.; Engel, Lawrence S.; Fenske, Richard A.; Fleming, Lora E.; Fletcher, Tony; Fontham, Elizabeth; Forastiere, Francesco; Frentzel-Beyme, Rainer; Fritschi, Lin; Gerin, Michel; Goldberg, Marcel; Grandjean, Philippe; Grimsrud, Tom K.; Gustavsson, Per; Haines, Andy; Hartge, Patricia; Hansen, Johnni; Hauptmann, Michael; Heederik, Dick; Hemminki, Kari; Hemon, Denis; Hertz-Picciotto, Irva; Hoppin, Jane A.; Huff, James; Jarvholm, Bengt; Kang, Daehee; Karagas, Margaret R.; Kjaerheim, Kristina; Kjuus, Helge; Kogevinas, Manolis; Kriebel, David; Kristensen, Petter; Kromhout, Hans; Laden, Francine; Lebailly, Pierre; LeMasters, Grace; Lubin, Jay H.; Lynch, Charles F.; Lynge, Elsebeth; ‘t Mannetje, Andrea; McMichael, Anthony J.; McLaughlin, John R.; Marrett, Loraine; Martuzzi, Marco; Merchant, James A.; Merler, Enzo; Merletti, Franco; Miller, Anthony; Mirer, Franklin E.; Monson, Richard; Nordby, Karl-Cristian; Olshan, Andrew F.; Parent, Marie-Elise; Perera, Frederica P.; Perry, Melissa J.; Pesatori, Angela Cecilia; Pirastu, Roberta; Porta, Miquel; Pukkala, Eero; Rice, Carol; Richardson, David B.; Ritter, Leonard; Ritz, Beate; Ronckers, Cecile M.; Rushton, Lesley; Rusiecki, Jennifer A.; Rusyn, Ivan; Samet, Jonathan M.; Sandler, Dale P.; de Sanjose, Silvia; Schernhammer, Eva; Costantini, Adele Seniori; Seixas, Noah; Shy, Carl; Siemiatycki, Jack; Silverman, Debra T.; Simonato, Lorenzo; Smith, Allan H.; Smith, Martyn T.; Spinelli, John J.; Spitz, Margaret R.; Stallones, Lorann; Stayner, Leslie T.; Steenland, Kyle; Stenzel, Mark; Stewart, Bernard W.; Stewart, Patricia A.; Symanski, Elaine; Terracini, Benedetto; Tolbert, Paige E.; Vainio, Harri; Vena, John; Vermeulen, Roel; Victora, Cesar G.; Ward, Elizabeth M.; Weinberg, Clarice R.; Weisenburger, Dennis; Wesseling, Catharina; Weiderpass, Elisabete; Zahm, Shelia Hoar

    2015-01-01

    , Cardis E, Cherrie JW, Christiani DC, Cocco P, Coggon D, Comba P, Demers PA, Dement JM, Douwes J, Eisen EA, Engel LS, Fenske RA, Fleming LE, Fletcher T, Fontham E, Forastiere F, Frentzel-Beyme R, Fritschi L, Gerin M, Goldberg M, Grandjean P, Grimsrud TK, Gustavsson P, Haines A, Hartge P, Hansen J, Hauptmann M, Heederik D, Hemminki K, Hemon D, Hertz-Picciotto I, Hoppin JA, Huff J, Jarvholm B, Kang D, Karagas MR, Kjaerheim K, Kjuus H, Kogevinas M, Kriebel D, Kristensen P, Kromhout H, Laden F, Lebailly P, LeMasters G, Lubin JH, Lynch CF, Lynge E, ‘t Mannetje A, McMichael AJ, McLaughlin JR, Marrett L, Martuzzi M, Merchant JA, Merler E, Merletti F, Miller A, Mirer FE, Monson R, Nordby KC, Olshan AF, Parent ME, Perera FP, Perry MJ, Pesatori AC, Pirastu R, Porta M, Pukkala E, Rice C, Richardson DB, Ritter L, Ritz B, Ronckers CM, Rushton L, Rusiecki JA, Rusyn I, Samet JM, Sandler DP, de Sanjose S, Schernhammer E, Seniori Costantini A, Seixas N, Shy C, Siemiatycki J, Silverman DT, Simonato L, Smith AH, Smith MT, Spinelli JJ, Spitz MR, Stallones L, Stayner LT, Steenland K, Stenzel M, Stewart BW, Stewart PA, Symanski E, Terracini B, Tolbert PE, Vainio H, Vena J, Vermeulen R, Victora CG, Ward EM, Weinberg CR, Weisenburger D, Wesseling C, Weiderpass E, Zahm SH. 2015. IARC Monographs: 40 years of evaluating carcinogenic hazards to humans. Environ Health Perspect 123:507–514; http://dx.doi.org/10.1289/ehp.1409149 PMID:25712798

  4. Neurose traumática, neurose de transferência: um relato autobiográfico do holocausto Neurosis traumática, neurosis de transferencia: un relato autobiográfico do holocausto Traumatic neurostaçãois, transference neurosis: an autobiographical account of the holocaust

    Directory of Open Access Journals (Sweden)

    Gustavo Adolfo Ramos Mello Neto

    2012-09-01

    Full Text Available Trata-se de tomar em conta neuroses que se desenvolvem a partir de um trauma explícito, ocorrido na realidade material, mas que se apresentam com algumas características de neuroses de transferência. Expõe-se, então, algo da descrição clássica da neurose traumática e, em seguida, um relato autobiográfico da escritora franco-judia Sarah Kofman, que passou sua infância na França durante a Segunda Guerra Mundial, teve seu pai morto em Auschwitz e foi obrigada a viver escondida durante esse período. Discute-se, de um lado, o objeto, a partir da perda, e o jogo que se estabelece com ele e, de outro, o trauma em si. Busca-se mostrar que a interação entre essas duas correntes forma uma trama complexa, talvez responsável pelas características de neurose de transferência, mais do que de neurose traumática. O erótico, no sentido fálico-edípico, parece ser o que produz essa complexidade, funcionando como fator de elaboração do trauma.Se trata de considerar las neurosis que se desarrollan a partir de un trauma explícito, ocurrido a partir de la realidad material, pero, que se presentan con algunas características de neurosis de transferencia. Se expone, así, algo de la descripción clásica de la neurosis traumática y, en seguida, un relato autobiográfico de la escritora franco-judía Sarah Kofman, que pasó su infancia en Francia durante la Segunda Guerra Mundial, perdió a su padre en Auschwitz y fue obligada a vivir escondida durante todo ese tiempo.Se discute, por un lado, el objeto, a partir de la pérdida, y el juego que se establece con él y, por otro, el trauma en sí. Buscamos enseñar que la interacción entre estas dos corrientes forma una trama compleja, tal vez responsable por las características de neurosis de transferencia, más que de neurosis traumática. Lo erótico, en el sentido fálico-edípico, parecer ser lo que produce esa complejidad, funcionando como factor de elaboración del trauma.This text takes

  5. Numerical simulation of surface solar radiation over Southern Africa. Part 1: Evaluation of regional and global climate models

    Science.gov (United States)

    Tang, Chao; Morel, Béatrice; Wild, Martin; Pohl, Benjamin; Abiodun, Babatunde; Bessafi, Miloud

    2018-02-01

    This study evaluates the performance of climate models in reproducing surface solar radiation (SSR) over Southern Africa (SA) by validating five Regional Climate Models (RCM, including CCLM4, HIRHAM5, RACMO22T, RCA4 and REMO2009) that participated in the Coordinated Regional Downscaling Experiment program over Africa (CORDEX-Africa) along with their ten driving General Circulation Models (GCMs) from the Coupled Model Intercomparison Project Phase 5 over SA. The model simulated SSR was thereby compared to reference data from ground-based measurements, satellite-derived products and reanalyses over the period 1990-2005. Results show that (1) the references obtained from satellite retrievals and reanalyses overall overestimate SSR by up to 10 W/m2 on average when compared to ground-based measurements from the Global Energy Balance Archive, which are located mainly over the eastern part of the southern African continent. (2) Compared to one of the satellite products (Surface Solar Radiation Data Set—Heliosat Edition 2; SARAH-2): GCMs overestimate SSR over SA in terms of their multi-model mean by about 1 W/m2 (compensation of opposite biases over sub-regions) and 7.5 W/m2 in austral summer and winter respectively; RCMs driven by GCMs show in their multimodel mean underestimations of SSR in both seasons with Mean Bias Errors (MBEs) of about - 30 W/m2 in austral summer and about - 14 W/m2 in winter compared to SARAH-2. This multi-model mean low bias is dominated by the simulations of the CCLM4, with negative biases up to - 76 W/m2 in summer and - 32 W/m2 in winter. (3) The discrepancies in the simulated SSR over SA are larger in the RCMs than in the GCMs. (4) In terms of trend during the "brightening" period 1990-2005, both GCMs and RCMs (driven by European Centre for Medium-Range Weather Forecasts Reanalysis ERA-Interim, short as ERAINT and GCMs) simulate an SSR trend of less than 1 W/m2 per decade. However, variations of SSR trend exist among different references data

  6. Lipofuscinose ceróide neuronal: achados clínicos e neurorradiológicos Neuronal ceroid lipofuscinosis: clinical and neuroradiological findings

    Directory of Open Access Journals (Sweden)

    Rômulo Lopes Gama

    2007-06-01

    Full Text Available Lipofuscinose ceróide neuronal (LCN constitui um grupo de doenças neurodegenerativas caracterizadas pelo depósito anormal de uma substância autofluorescente de lipopigmentos, que lembra ceróide e lipofuscina, dentro dos lisossomos dos neurônios e outros tipos de células. Os principais subtipos fenotípicos, baseando-se na idade de início, curso clínico e morfologia ultraestrutural, são classificados em formas infantil, infantil tardia, juvenil e adulta. Seis genes associados a lipofuscinose ceróide foram identificados e aproximadamente 150 mutações também são descritas. Relatamos sete pacientes com LCN baseados na história clínica, achados neurorradiológicos e patológicos avaliados na Rede Sarah de Hospitais de Reabilitação - Fortaleza - Ceará - Brasil. Cinco casos foram confirmados com biópsia de pele, sendo dois casos irmãos de pacientes confirmados. O diagnóstico precoce de LCN, uma doença com herança autossômica recessiva, é mandatório para aconselhamento genético e prevenção de outros casos na família. Os achados de imagem podem contribuir no diagnóstico diferencial.The neuronal ceroid lipofuscinoses (NCL are a group of neurodegenerative disorders, characterized by abnormal storage of an autofluorescent substance of lipopigments, resembling ceroid and lipofuscin, within lysosomes of neurons and other types of cells. The main phenotypic subtypes have been established on the basis of age of onset, clinical course, and ultra structural morphology, and classified as infantile, late infantile, juvenile and adult forms. Six genes have been associated with human NCL and approximately 150 mutations have been described. The aim of this study is to report the clinical, neuroradiological, and morphological characteristics of seven patients evaluated at Sarah Network of Hospitals for Reabilitation - Fortaleza - Ceará - Brazil. Five cases were histopathologically confirmed with skin biopsy and two were siblings of

  7. Schriftstellerinnen der DDR und feministisches Bewußtsein im Staatssozialismus GDR Women Authors and Feminist Consciousness During State Socialism

    Directory of Open Access Journals (Sweden)

    Eva Kaufmann

    2001-11-01

    Full Text Available Seit den 1960er Jahren produzierten Schriftstellerinnen in der DDR wie Christa Wolf, Irmtraud Morgner, Sarah Kirsch, Brigitte Reimann, Charlotte Worgitzky, Lia Pirskawetz, und Maya Wiens eine vielfältige Literatur zu frauenrelevanten Themen. Den Obertitel „The Promised Land“ (das gelobte Land hat Lorna Martens Irmtraud Morgner entlehnt, der Autorin, die sie neben Christa Wolf als wichtigste Zeugin für „feminist writing“ in der DDR betrachtet. In Morgners Roman Leben und Abenteuer der Trobadora Beatriz steht der Begriff „gelobtes Land“ bezogen auf die DDR in einem ironischen Zusammenhang. Mit simplem Jaja oder Neinnein ist diesem „Ort des Wunderbaren“ (Morgner nicht beizukommen. Vergleichbares signalisiert auch das Fragezeichen, das Martens hinter den Begriff „Promised Land“ setzt. Der anspielungsreiche Verweis auf das Land erscheint auch insofern nützlich, als die Eigenart feministischen Schreibens genauer zu fassen ist, wenn über das Land selbst, namentlich seine Frauenpolitik, Auskünfte gegeben werden. Lorna Martens möchte herausfinden, wie Schriftstellerinnen in der DDR feministisches Bewusstsein artikuliert haben, d.h. feministisches Bewusstsein unter den vom Staatssozialismus geschaffenen Bedingungen.From the 1960s on, women writers in the German Democratic Republic (GDR, including Christa Wolf, Irmtraud Morgner, Sarah Kirsch, Brigitte Reimann, Charlotte Worgitzky, Lia Pirskawetz, and Maya Wiens, produced a large body of writing on women’s issues. Martens wants to investigate how these women authors in the GDR have articulated their feminist consciousness under the conditions of state socialism. Martens’ use of the title The Promised Land is an allusion to a book by Irmtraud Morgner, an author whom, along with Christa Wolf, Martens considers one of the most important witnesses of feminist writing in the GDR. In Morgner’s book The Life and Adventures of Troubadour Beatriz the term “promised land” is being

  8. A teologia, o feminino Theology and the feminine

    Directory of Open Access Journals (Sweden)

    Adriana Valerio

    2005-08-01

    Full Text Available O artigo retrata exemplos de mulheres e místicas que leram a Bíblia de uma forma nova e diferente de como a secular tradição masculina fez. Elas conseguiram reinterpretar sua experiência de fé com palavras originais e manifestam uma subjetividade cheia de dúvidas expressa sabiamente pelo uso da ironia. São elas: Domenica Narducci da Paradiso (+1553, que comenta com grande coragem a famosa proibição paulina "As mulheres calem em assembléia" (1Cor 14,34; Arcangela Tarabotti (+1652, que sem temor denuncia o escândalo dos enclausuramentos forçados; Sarah Grimké (+1873, que leva adiante uma leitura emancipacionista e igualitária das Sagradas Escrituras; Elisa Salerno (+1957, que encontra na má interpretação da Bíblia os fundamentos da exclusão feminina e acusa a Igreja Católica de "heresia antifeminista". O rastro de pensadoras nunca se exauriu e retoma vigor nos dias atuais com os estudos e as reflexões de teólogas que impulsionam suas igrejas a buscar novos modos de viver a igualdade e a diversidade, com o intuito de reconhecer na diversidade um valor imprescindível para a fé no Deus Uno e Trino.The essay presents some examples of women and mystics who have read the Bible differently from the age-old male tradition. They have been able to reinterpret their own experience of faith using a new language, showing a doubtful subjectivity skillfully expressed through irony. They are: Domenica Narducci da Paradiso (+1553, who courageously comments on the famous prohibition ofSt. Paul that "Women must be silent in the assembly" (1Cor 14,34; Arcangela Tarabotti (+1652, who does not fear to denounce the scandal of compulsory wows; Sarah Grimké (+1873, who carries out a reading of the Holy Texts in the light of the emancipation and equality; Elisa Salerno (+1957, who characterizes the roots of female marginalization in the tendentious interpretation of the Bible and accuses the Catholic church of "anti-feministic heresy". Such a

  9. Anthropologists in/of the neoliberal academy

    Directory of Open Access Journals (Sweden)

    Tracey Heatherington

    2016-08-01

    Full Text Available Questo Forum raccoglie brevi interventi di antropologi che con ruoli diversi lavorano in differenti contesti universitari, allo scopo di riflettere su recenti esperienze di riforme neoliberiste del sistema pubblico dell'istruzione superiore. I contributi esplorano processi di neoliberalizzazione dell'università e cambiamenti istituzionali in corso in Australia e Nuova Zelanda, Romania, Danimarca, Grecia, Finlandia, Messico, Stati Uniti, Olanda, Spagna, Canada e Regno Unito. L'obiettivo è quello di costruire una piattaforma che possa ospitare riflessioni critiche sulle trasformazioni attuali dell'accademia e delle relative implicazioni per il futuro dell'antropologia. Auspichiamo che il Forum serva anche a indurre i colleghi alle prese con le conseguenze del vigente regime di austerità a formare una coalizione in favore di una idea di università diversa da quella oggi dominante. Contributi di Cris Shore & Susan Wright, Vintilă Mihăilescu, Sarah F. Green, Gabriela Vargas-Cetina & Steffan Igor Ayora-Diaz, Tracey Heatherington, Dimitris Dalakoglou, Noelle Molé Liston, Susana Narotzky, Jaro Stacul, Meredith Welch-Devine, Jon P. Mitchell.

  10. Recent development in clusters of rare earths and actinides. Chemistry and materials

    International Nuclear Information System (INIS)

    Zheng, Zhiping

    2017-01-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  11. The pollen of metaphor: Box, cage, and trap as containment in the eighteenth century.

    Science.gov (United States)

    Milne, Anne

    2016-06-01

    This article uses the concept of "the pollen of metaphor" to discuss three forms of non-human animal containment in the eighteenth century: François Huber's Leaf or Book Hive bee box first described in his Nouvelles Observations sur les Abeilles (1792, English translation 1806), Sarah Trimmer's bird cages in her didactic children's book, Fabulous Histories; Or, The Story of the Robins (1786), and a mouse trap in Anna Letitia Barbauld's 1773 poem, "The Mouse's Petition, found in the trap where he had been confined all night by Dr. Priestley, for the sake of making experiments with different kinds of air." All three works highlight the eighteenth-century art of observation. The inherent commitment to relationships in the observation process suggests that interpreting ocular evidence involves "plausible relations," metaphor and/or "productive analogy." The article teases out subtle differences between the ways that each author uses containments and concludes that while Huber seeks to circumscribe non-human animal behavior within the bounds of 'reasonable' animal husbandry to better serve human needs, Trimmer goes further to connect 'appropriate' non-human animal containment to moral strictures governing humans. Barbauld's intervention using a literate, speaking animal subject confronts such moral governance to argue for equal rights based on principles of true equality rather than what is observed to be 'reasonable' and/or 'moral.' Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. The Secret Life of Archives: Sally Siddons, Sir Thomas Lawrence, and The Material of Memory

    Directory of Open Access Journals (Sweden)

    Laura Engel

    2014-03-01

    Full Text Available This essay is in two parts, in the first I attempt to map out strategies for considering archival materials through the lens of performance, and in the second I enact or perform some of those strategies through a close reading of a letter from Sally Siddons, daughter of the famous actress Sarah Siddons, to the renown portrait painter and rakish bad boy, Sir Thomas Lawrence. I present a methodology that considers archival researchers as tourists who approach archival objects and images as material for curating a virtual exhibition. I argue that this strategy allows us to recognize and attempt to envision the interdisciplinary relationship amongst archival materials in order to imagine them in spatial, theatrical, and visual proximity to one another. In this way as researchers we are performing a kind of re-enactment, an animation, of the secret life of archives, which attempts to account the embodied traces of the past by providing an accessible thought provoking map for audiences.

  13. Dilemas éticos da vida humana: a trajetória hospitalar de crianças portadoras de paralisia cerebral grave

    Directory of Open Access Journals (Sweden)

    Debora Diniz

    Full Text Available O artigo é um estudo antropológico que aborda os pressupostos éticos do tratamento médico ministrado em crianças portadoras de paralisia cerebral grave. A pesquisa foi realizada a partir de um trabalho etnográfico de oito meses, com pacientes em tratamento no Centro de Paralisia Cerebral do Hospital Sarah, Salvador. A observação da terapêutica ministrada a estas crianças, que apresentam pouquíssimas mudanças do quadro clínico, levou ao questionamento já bastante sugerido em discussões relativas à deontologia médica: Qual o objetivo do tratamento médico empregado nestas crianças? Na verdade, os resultados desta pesquisa indicaram a existência de explicações sócio-humanistas que estariam além da explicação médico-científica oficial, a qual resumiria a terapêutica a um fisicalismo corporal.

  14. Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability.

    Science.gov (United States)

    Arimori, Takao; Kitago, Yu; Umitsu, Masataka; Fujii, Yuki; Asaki, Ryoko; Tamura-Kawakami, Keiko; Takagi, Junichi

    2017-10-03

    Antibody fragments are frequently used as a "crystallization chaperone" to aid structural analysis of complex macromolecules that are otherwise crystallization resistant, but conventional fragment formats have not been designed for this particular application. By fusing an anti-parallel coiled-coil structure derived from the SARAH domain of human Mst1 kinase to the variable region of an antibody, we succeeded in creating a novel chimeric antibody fragment of ∼37 kDa, termed "Fv-clasp," which exhibits excellent crystallization compatibility while maintaining the binding ability of the original IgG molecule. The "clasp" and the engineered disulfide bond at the bottom of the Fv suppressed the internal mobility of the fragment and shielded hydrophobic residues, likely contributing to the high heat stability and the crystallizability of the Fv-clasp. Finally, Fv-clasp antibodies showed superior "chaperoning" activity over conventional Fab fragments, and facilitated the structure determination of an ectodomain fragment of integrin α6β1. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Ageism and its clinical impact in oncogeriatry: state of knowledge and therapeutic leads

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    Schroyen S

    2014-12-01

    Full Text Available Sarah Schroyen,1 Stéphane Adam,1 Guy Jerusalem,2,3 Pierre Missotten1 1University of Liège, Psychology of Aging Unit, 2University of Liège, Laboratory of Medical Oncology, 3CHU Sart Tilman Liege, Department of Medical Oncology, Liège, Belgium Abstract: Cancer is a major health problem that is widespread in elderly people. Paradoxically, older people suffering from cancer are often excluded from clinical trials and are undertreated when compared to younger patients. One explanation for these observations is age stigma (ie, stereotypes linked to age, and thus ageism. These stigmas can result in deleterious consequences for elderly people’s mental and physical health in “normal” aging. What, then, is the impact in a pathological context, such as oncology? Moreover, health care professionals’ attitudes can be tainted with ageism, thus leading to undesirable consequences for patients. To counter these stigmas, we can apply some possible interventions emerging from research on normal aging and from social psychology, such as intergenerational contact, activation of positive stereotypes, self-affirmation, and so on; these tools can improve opinions of aging among the elderly people themselves, as well as health care professionals, thus affecting patients’ mental and physical health. Keywords: oncogeriatry, clinical approaches, stigmatization, ageism

  16. The association between self-injurious behaviors and autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Minshawi NF

    2014-04-01

    Full Text Available Noha F Minshawi,1 Sarah Hurwitz,2 Jill C Fodstad,1 Sara Biebl,3 Danielle H Morriss,4 Christopher J McDougle51Department of Psychiatry, Indiana University School of Medicine, Christian Sarkine Autism Treatment Center, James Whitcomb Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA; 2School of Education, Indiana University, Bloomington, IN, USA; 3Child and Adolescent Behavioral Health, Sanford Health, Fargo, ND, USA; 4Medical College of South Carolina, Charleston, SC, USA; 5Departments of Psychiatry and Pediatrics, Lurie Center for Autism, Massachusetts General Hospital and MassGeneral Hospital for Children, Harvard Medical School, Boston, MA, USAAbstract: A key area of concern in children with autism spectrum disorders (ASDs are self-injurious behaviors (SIBs. These are behaviors that an individual engages in that may cause physical harm, such as head banging, or self-biting. SIBs are more common in children with ASD than those who are typically developing or have other neurodevelopmental disabilities. Therefore, it is important that clinicians who work with children with ASD have a solid understanding of SIB. The purpose of this paper is to review the research on the epidemiology of SIB in children with ASD, factors that predict the presence of SIB in this population, and the empirically supported behavioral treatments available.Keywords: self-injury, autism spectrum disorders, applied behavior analysis

  17. Open Praxis, volumen 4 issue 1

    Directory of Open Access Journals (Sweden)

    Editor Open Praxis

    2010-03-01

    Full Text Available - Correlation between Performance and Quality of Academic Staff in National Open University of Nigeria (NOUN Olubiyi Adeniyi Adewale, Timothy Olugbenga Ajadi & Juliet O.Inegbedion (1-7 - Benchmarking E-Learning in UK Universities: Lessons from and for the International Context Paul Bacsich (9-17 - Structural equation modelling of factors affecting success in student’s performance in ODL-Programs: Extending Quality Management concepts Per Bergamin, Simone Ziska & Rudolf Groner (18-25 - Quality Assurance in Open and Distance Learning in India S.K. Gandhe (26-32 - Leading innovative approaches to the financial crisis Sarah Guri-Rosenblit (33-38 - TOWARDS KNOWLEDGE BASED ECONOMIES - the contribution of open distance learning strategies in addressing equity and inclusiveness issues in small states like Mauritius Jheengut (39-63 - New Approaches to Quality Assurance in the Changing World of Higher Education Maria Jose Lemaitre (64-75 - Entrepreneurship: New Challenges for Higher Education Institutions Josep Lladós (76-87 - A Psychometric Study in the Performance of Distance learners Ravi K Mahajan (88-94 - Managing Quality Assurance for Distance Learning Programs in Malaysia Mohd Ismail Ramli (95-101 - Employability and lifelong learning Hazel Simmons-McDonald (102-113

  18. The Newton papers the strange and true odyssey of Isaac Newton's manuscripts

    CERN Document Server

    Dry, Sarah

    2014-01-01

    When Isaac Newton died at 85 without a will on March 20, 1727, he left a mass of disorganized papers-upwards of 8 million words-that presented an immediate challenge to his heirs. Most of these writings, on subjects ranging from secret alchemical formulas to impassioned rejections of the Holy Trinity to notes and calculations on his core discoveries in calculus, universal gravitation, and optics, were summarily dismissed by his heirs as "not fit to be printed." Rabidly heretical, alchemically obsessed, and possibly even mad, the Newton presented in these papers threatened to undermine not just his personal reputation but the status of science itself. As a result, the private papers of the world's greatest scientist remained hidden to all but a select few for over two hundred years. In The Newton Papers, Sarah Dry divulges the story of how this secret archive finally came to light-and the complex and contradictory man it revealed. Covering a broad swath of history, Dry explores who controlled Newton's legacy, ...

  19. Tasmanian tigers and polar bears: The documentary moving image and (species loss

    Directory of Open Access Journals (Sweden)

    Belinda Smaill

    2015-04-01

    Full Text Available In this essay I explore how two divergent examples of the nonfiction moving image can be understood in relation to the problem of representing species loss. The species that provide the platform for this consideration are the thylacine, better known as the Tasmanian tiger, and the polar bear. They represent the two contingencies of species loss: endangerment and extinction. My analysis is structured around moving images from the 1930s of the last known thylacine and the very different example of Arctic Tale (Adam Ravetch, Sarah Robertson, 2007, a ‘Disneyfied’ film that dramatises climate change and its impact on the polar bear. Species loss is frequently perceived in a humanist sense, reflecting how we ‘imagine ourselves’ or anthropocentric charactersations of non-human others. I offer a close analysis of the two films, examining the problem of representing extinction through a consideration of the play of absence and presence, vitality and extinguishment, that characterises both the ontology of cinema and narratives about species loss.

  20. Important aspects of midwifery

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    E. Barnett

    1980-09-01

    Full Text Available The art of midwifery must be one of the oldest of acquired skills. In prehistoric times, the more experienced women assisted and comforted their younger relatives during parturition. There are scattered references to midwives in ancient literature, including the Bible. In Genesis 35:17 we learn that Rachel’s death was the result of “ hard labour” . One should congratulate the midwife who delivered Sarah of a son at the age of 90 years - Genesis 17:17. Midwifery stagnated during the Middle Ages due, partly to the ignorance of the midwives as well as to a lack of knowledge of human anatomy coupled with the accepted teaching of the ancients, which was regarded as the ultimate authority. Great advances in the art and science of midwifery have occurred since the Middle Ages, amounting to a revolution in thought and practice. Less than 100 years ago, in 1898, in W.S. Playfair’s “Science and Practice of Midwifery” no mention was made of any form of antenatal examination or even of the testing of urine for albumin. Times have indeed changed - today the whole concept of maternal and child care would be quite unrecognisable to a Victorian midwife. We have also accepted the male midwife into our midst.

  1. Ageism in Belgium and Burundi: a comparative analysis

    Directory of Open Access Journals (Sweden)

    Marquet M

    2016-08-01

    Full Text Available Manon Marquet, Pierre Missotten, Sarah Schroyen, Desiderate Nindaba, Stéphane Adam Psychology of Aging Unit, University of Liège, Liège, Belgium Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than from the culture itself. We tested this assumption by conducting a survey among people living in a least developed country compared with those living in a developed country.Participants and methods: Twenty-seven Belgians living in Belgium, 29 Burundians living in Belgium, and 32 Burundians living in Burundi were included in this study. Their attitudes toward older adults were assessed using several self-reported measures.Results: Statistical analyses confirmed that older people are more negatively perceived by Burundians living in Burundi than by Burundians and Belgians living in Belgium, whose attitudes did not differ from each other.Conclusion: Consistent with our hypothesis, our results suggest that the level of development of a country and more particularly the lack of government spending on older people (pension and health care systems may contribute to their younger counterparts perceiving them more negatively. Keywords: attitudes toward older adults, cross-cultural differences, socioeconomic development, intergenerational relations

  2. HIF-mediated innate immune responses: cell signaling and therapeutic implications

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    Harris AJ

    2014-05-01

    Full Text Available Alison J Harris, AA Roger Thompson, Moira KB Whyte, Sarah R Walmsley Academic Unit of Respiratory Medicine, Department of Infection and Immunity, University of Sheffield, Sheffield, UK Abstract: Leukocytes recruited to infected, damaged, or inflamed tissues during an immune response must adapt to oxygen levels much lower than those in the circulation. Hypoxia inducible factors (HIFs are key mediators of cellular responses to hypoxia and, as in other cell types, HIFs are critical for the upregulation of glycolysis, which enables innate immune cells to produce adenosine triphosphate anaerobically. An increasing body of evidence demonstrates that hypoxia also regulates many other innate immunological functions, including cell migration, apoptosis, phagocytosis of pathogens, antigen presentation and production of cytokines, chemokines, and angiogenic and antimicrobial factors. Many of these functions are mediated by HIFs, which are not only stabilized posttranslationally by hypoxia, but also transcriptionally upregulated by inflammatory signals. Here, we review the role of HIFs in the responses of innate immune cells to hypoxia, both in vitro and in vivo, with a particular focus on myeloid cells, on which the majority of studies have so far been carried out. Keywords: hypoxia, neutrophils, monocytes, macrophages

  3. Supersymmetric and non-supersymmetric models without catastrophic Goldstone bosons

    Energy Technology Data Exchange (ETDEWEB)

    Braathen, Johannes; Goodsell, Mark D. [LPTHE, UPMC Univ. Paris 6, Sorbonne Universites, Paris (France); LPTHE, CNRS, Paris (France); Staub, Florian [Karlsruhe Institute of Technology, Institute for Theoretical Physics (ITP), Karlsruhe (Germany); Karlsruhe Institute of Technology, Institute for Nuclear Physics (IKP), Eggenstein-Leopoldshafen (Germany)

    2017-11-15

    The calculation of the Higgs mass in general renormalisable field theories has been plagued by the so-called ''Goldstone Boson Catastrophe'', where light (would-be) Goldstone bosons give infra-red divergent loop integrals. In supersymmetric models, previous approaches included a workaround that ameliorated the problem for most, but not all, parameter space regions; while giving divergent results everywhere for non-supersymmetric models. We present an implementation of a general solution to the problem in the public code SARAH, along with new calculations of some necessary loop integrals and generic expressions. We discuss the validation of our code in the Standard Model, where we find remarkable agreement with the known results. We then show new applications in Split SUSY, the NMSSM, the Two-Higgs-Doublet Model, and the Georgi-Machacek model. In particular, we take some first steps to exploring where the habit of using tree-level mass relations in non-supersymmetric models breaks down, and show that the loop corrections usually become very large well before naive perturbativity bounds are reached. (orig.)

  4. Scientists Like Me: Faces of Discovery

    Science.gov (United States)

    Enevoldsen, A. A. G.; Culp, S.; Trinh, A.

    2010-08-01

    During the International Year of Astronomy, Pacific Science Center is hosting a photography exhibit: Scientists Like Me: Faces of Discovery. The exhibit contains photographs of real, current astronomers and scientists working in astronomy and aerospace-related fields from many races, genders, cultural affiliations and walks of life. The photographs were taken and posters designed by Alyssa Trinh and Sarah Culp, high school interns in Discovery Corps, Pacific Science Center's youth development program. The direct contact between the scientists and the interns helps the intended audience of teachers and families personally connect with scientists. The finished posters from this exhibit are available online (http://pacificsciencecenter.org/scientists) for teachers to use in their classrooms, in addition to being displayed at Pacific Science Center and becoming part of Pacific Science Center's permanent art rotation. The objective of this project was to fill a need for representative photographs of scientists in the world community. It also met two of the goals of International Year of Astronomy: to provide a modern image of science and scientists, and to improve the gender-balanced representation of scientists at all levels and promote greater involvement by all people in scientific and engineering careers. We would like to build on the success of this project and create an annual summer internship, with different interns, focusing on creating posters for different fields of science.

  5. Reviewing the options for local estrogen treatment of vaginal atrophy

    Directory of Open Access Journals (Sweden)

    Lindahl SH

    2014-03-01

    Full Text Available Sarah H Lindahl Sutter East Bay Medical Foundation, SEBMF – Diablo Division, Castro Valley, CA, USA Background: Vaginal atrophy is a chronic condition with symptoms that include vaginal dryness, pain during sex, itching, irritation, burning, and discharge, as well as various urinary problems. Up to 45% of postmenopausal women may be affected, but it often remains underreported and undertreated. This article aims to review the current recommendations for treatment of vaginal atrophy, and current data on the effectiveness and safety of local vaginal estrogen therapies. Methods: Literature regarding vaginal atrophy (2007–2012 was retrieved from PubMed and summarized, with emphasis on data related to the treatment of vaginal atrophy with local vaginal estrogen therapy. Results: Published data support the effectiveness and endometrial safety of low-dose local estrogen therapies. These results further support the general recommendation by the North American Menopause Society that a progestogen is not needed for endometrial protection in patients using low-dose local vaginal estrogen. Benefits of long-term therapy for vaginal atrophy include sustained relief of symptoms as well as physiological improvements (eg, decreased vaginal pH and increased blood flow, epithelial thickness, secretions. Conclusion: Currently available local vaginal estrogen therapies are well tolerated and effective in relieving symptoms of vaginal atrophy. Recent data support the endometrial safety of low-dose regimens for up to 1 year. Keywords: menopause, estrogen, local estrogen therapy, vaginal atrophy

  6. On Judith Butler: A Phenomenology of Lived, narrated and Represented Embodiment

    Directory of Open Access Journals (Sweden)

    Olga Belmonte García

    2017-07-01

    Full Text Available In this paper we take Judith Butler’s thinking as a basis from which to consider the ideas of three authors. In our view, these authors complement Butler’s project of helping excluded people to fight for a dignified life, a “liveable life”; and specifically to the idea of using performative resignifications of discourses and practices. On one hand, we present the writings of Sarah Ahmed and Lanei Rodemeyer; they consider the spatiality and temporality of the lived body (Ahmed and the relationship between the lived body and discourse (Rodemeyer. In both cases, “pure phenomenology” (and not hermeneutics is applied to the question of sexual diversity. On the other hand, we delve into the works of Louise Bourgeois, for whom artistic creation is a way of exorcising pain and becoming free of socially constructed prisons. Starting from the paths opened by these authors, we believe that a phenomenology is possible in which there is place for what does not fit into the norm. this phenomenology would make it possible, on one side, to rend visibility to those who do not fit into the established norms and categories and, on another side, to contribute to a reformulation of discourse, such a transformation that allows the excluded to inhabit them. “Pure” phenomenology, that aims at going to “the things themselves” do not naturalise oppressions, but it is rather an ally to recognise, denounce and provide a reparation for them.

  7. Taus at ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Demers, Sarah M. [Yale Univ., New Haven, CT (United States). Dept. of Physics

    2017-12-06

    The grant "Taus at ATLAS" supported the group of Sarah Demers at Yale University over a period of 8.5 months, bridging the time between her Early Career Award and her inclusion on Yale's grant cycle within the Department of Energy's Office of Science. The work supported the functioning of the ATLAS Experiment at CERN's Large Hadron Collider and the analysis of ATLAS data. The work included searching for the Higgs Boson in a particular mode of its production (with a W or Z boson) and decay (to a pair of tau leptons.) This was part of a broad program of characterizing the Higgs boson as we try to understand this recently discovered particle, and whether or not it matches our expectations within the current standard model of particle physics. In addition, group members worked with simulation to understand the physics reach of planned upgrades to the ATLAS experiment. Supported group members include postdoctoral researcher Lotte Thomsen and graduate student Mariel Pettee.

  8. Is it morally permissible for hospital nurses to access prisoner-patients' criminal histories?

    Science.gov (United States)

    Neiman, Paul

    2016-01-01

    In the United States, information about a person's criminal history is accessible with a name and date of birth. Ruth Crampton has studied nurses' care for prisoner-patients in hospital settings and found care to be perfunctory and reactive. This article examines whether it is morally permissible for nurses in hospital settings to access information about prisoner-patients' criminal histories. Nurses may argue for a right to such information based on the right to personal safety at work or the obligation to provide prisoner-patients with the care that they deserve. These two arguments are considered and rejected. It is further argued that accessing information about a prisoner-patient's criminal history violates nurses' duty to care. Care, understood through Sarah Ruddick's account as work and relationship, requires nurses to be open and unbiased in order to do their part in forming a caring relationship with patients. Knowledge of a prisoner-patient's criminal history inhibits the formation of this relationship and thus violates nurses' duty to care.

  9. Recent development in clusters of rare earths and actinides. Chemistry and materials

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Zhiping (ed.) [Arizona Univ., Tucson, AZ (United States). Dept. of Chemistry and Biochemistry

    2017-02-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  10. Final Report- "An Algorithmic and Software Framework for Applied Partial Differential Equations (APDEC): A DOE SciDAC Integrated Software Infrastructure Center (ISIC)

    Energy Technology Data Exchange (ETDEWEB)

    Elbridge Gerry Puckett

    2008-05-13

    All of the work conducted under the auspices of DE-FC02-01ER25473 was characterized by exceptionally close collaboration with researchers at the Lawrence Berkeley National Laboratory (LBNL). This included having one of my graduate students - Sarah Williams - spend the summer working with Dr. Ann Almgren a staff scientist in the Center for Computational Sciences and Engineering (CCSE) which is a part of the National Energy Research Supercomputer Center (NERSC) at LBNL. As a result of this visit Sarah decided to work on a problem suggested by Dr. John Bell the head of CCSE for her PhD thesis, which she finished in June 2007. Writing a PhD thesis while working at one of the University of California (UC) managed DOE laboratories is a long established tradition at the University of California and I have always encouraged my students to consider doing this. For example, in 2000 one of my graduate students - Matthew Williams - finished his PhD thesis while working with Dr. Douglas Kothe at the Los Alamos National Laboratory (LANL). Matt is now a staff scientist in the Diagnostic Applications Group in the Applied Physics Division at LANL. Another one of my graduate students - Christopher Algieri - who was partially supported with funds from DE-FC02-01ER25473 wrote am MS Thesis that analyzed and extended work published by Dr. Phil Colella and his colleagues in 1998. Dr. Colella is the head of the Applied Numerical Algorithms Group (ANAG) in the National Energy Research Supercomputer Center at LBNL and is the lead PI for the APDEC ISIC which was comprised of several National Laboratory research groups and at least five University PI's at five different universities. Chris Algieri is now employed as a staff member in Dr. Bill Collins' research group at LBNL developing computational models for climate change research. Bill Collins was recently hired at LBNL to start and be the Head of the Climate Science Department in the Earth Sciences Division at LBNL. Prior to

  11. 18 Million Cracks, but No Cigar: News Media and the Campaigns of Clinton, Palin, and Bachmann

    Directory of Open Access Journals (Sweden)

    Nicole R. Foster Shoaf

    2016-09-01

    Full Text Available Decades of research within political science, political communication, and mass media found pervasive gender biased media coverage of female political candidates. However, recent research suggests that gender stereotypes do not have a consistent effect in all campaign environments and when gender stereotypes are not activated, female candidates are not disadvantaged. As a result, if we see a reduction in reliance on gender stereotypes in the media, female candidates should enjoy a more level playing field. In this analysis, we focus on mass media’s coverage of female candidates in elite executive political races. This study conducts a content analysis of media coverage of three recent women candidates for the United States’ highest executive offices: Senator Hillary Clinton, Congresswoman Michelle Bachmann, and Governor Sarah Palin. Our analysis of newspapers and television news coverage confirms the media do not discuss female and male candidates in neutral terms, but instead fall back onto traditional gender stereotypes and emphasize female candidates’ physical appearances and family roles far more frequently than they do for male candidates. This may, in turn, prime gender stereotypes in voters, impair candidates’ fundraising ability, and limit the electoral ambition of future generations of female candidates.

  12. Weighing Posthumanism: Fatness and Contested Humanity

    Directory of Open Access Journals (Sweden)

    Sofia Apostolidou

    2016-11-01

    Full Text Available Our project on fatness begins by turning attention to the multiple cultural instances in which fatness has been intrinsically linked with notions such as self—neglect and poor self—management. In Foucauldian terms, we analyse the fat subject as a failed homo economicus, an individual who has failed to be an “entrepreneur of himself, being for himself his own capital, being for himself his own producer, being for himself the source of [his] earnings” (Foucault, 2008, p. 226. From this perspective, we analyse instances of collective hatred towards fat subjects as direct results of the biopolitical triplet of responsibility, rationality, and morality. Morality is our bridge into the field of posthumanism, in which, as we demonstrate, these biopolitical imperatives also apply, reinforced by the field’s fascination with prosthetics and enhancement. Where, by biopolitical standards, fat subjects have failed to manage themselves, posthuman subjects find themselves guilty of not responsibly, rationally, and morally manipulating themselves to optimal productivity. Using criticism that disability studies scholars like Sarah S. Jain and Vivian Sobchack have voiced about posthumanism, we demonstrate the ways in which, within posthumanism, all subjects can be found as lacking when compared to their potential, enhanced post­human version.

  13. Quality of life and wishes in Duchenne Muscular Dystrophy: the perception of children and their parents

    Directory of Open Access Journals (Sweden)

    Benito Arias Martínez

    2009-12-01

    Full Text Available Objective: To assess the agreement between children with Duchenne Muscular Dystrophy (DMD and their parents regarding the perception of quality of life (QOL and the wishes expressed by children. Methods: The study involved 14 patients (median age = 9.9 yearsold followed up in Sarah Rehabilitation Center – Fortaleza, Brazil and their parents. The following instruments were used: AUQEI questionnaire (Autoquestionnaire Qualité de Vie Enfant Imagé and Three Wishes Projective Technique, this being analyzed by Nereo & Hinton’s system of categories (2003. Results: The analysis of AUQEI showed a good agreement with ICC (intraclass correlation coefficient = 0,699 and a positive and significant correlation between scores of both children and their parents (rho = 0.54, p < 0.05. The Three Wishes also showed a good agreement, mainly in the categories of Material Goods and Activities. Conclusions: Despite children with DMD and their parents exhibited similar perceptions of the QOL and wishes, we suggest that both be heard in respect to aspects of the rehabilitation program. This study provides additional data concerning the need for child QOL assessment instruments that include parallel versions directed to the children and their parents.

  14. Quality of life and swallowing questionnaire for individuals with Parkinson's disease: development and validation.

    Science.gov (United States)

    Diniz, Juliana Garcia; da Silva, Alfredo Carlos; Nóbrega, Ana Caline

    2018-05-21

    Individuals with Parkinson's disease (PD) may exhibit some degree of change in swallowing dynamics during the course of the disease. These changes can affect their physical, functional and emotional quality of life. To develop a quality of life and swallowing questionnaire for individuals with PD. The first version of the questionnaire comprised 29 items taken from the accounts of 50 patients treated over a 2-month period at Sarah Hospital in Salvador, Bahia, Brazil. A committee of 10 experts in the field analyzed the content and reduced the questionnaire to 28 questions. The questionnaire was then administered to 140 PD patients and 47 healthy individuals. A factor analysis of the items guided the drafting of the final questionnaire, which consisted of 19 items grouped into four factors, encompassing physical, functional and emotional aspects. A test-retest assessment was conducted with 44 individuals with PD. The internal consistency, estimated by the mean of Cronbach's alpha coefficient, varied between 0.71 (domain 3) and 0.94 (domain 1) in the test and between 0.69 (domain 3) and 0.95 (domain 1) in the retest. The correlation coefficient in the test/retest comparison was high and significant, demonstrating that the measurement was stable. A significant difference was observed between the PD group and the comparison group. The questionnaire developed is a valid, statistically appropriate and clinically effective self-administered instrument for individuals with PD. © 2018 Royal College of Speech and Language Therapists.

  15. Dilemas éticos da vida humana: a trajetória hospitalar de crianças portadoras de paralisia cerebral grave

    Directory of Open Access Journals (Sweden)

    Diniz Debora

    1996-01-01

    Full Text Available O artigo é um estudo antropológico que aborda os pressupostos éticos do tratamento médico ministrado em crianças portadoras de paralisia cerebral grave. A pesquisa foi realizada a partir de um trabalho etnográfico de oito meses, com pacientes em tratamento no Centro de Paralisia Cerebral do Hospital Sarah, Salvador. A observação da terapêutica ministrada a estas crianças, que apresentam pouquíssimas mudanças do quadro clínico, levou ao questionamento já bastante sugerido em discussões relativas à deontologia médica: Qual o objetivo do tratamento médico empregado nestas crianças? Na verdade, os resultados desta pesquisa indicaram a existência de explicações sócio-humanistas que estariam além da explicação médico-científica oficial, a qual resumiria a terapêutica a um fisicalismo corporal.

  16. Treatment of post-partum depression: a review of clinical, psychological and pharmacological options

    Directory of Open Access Journals (Sweden)

    Elizabeth Fitelson

    2010-12-01

    Full Text Available Elizabeth Fitelson1, Sarah Kim4, Allison Scott Baker3, Kristin Leight21Director, 2Attending Psychiatrist, TheWomen's Program, 3Child and Adolescent Psychiatry Fellow, Division of Child Psychiatry, 4PGY-I Resident in Psychiatry, Department of Psychiatry, Columbia University Medical Center, New York, NY, USAAbstract: Postpartum depression (PPD is a common complication of childbearing, and has increasingly been identified as a major public health problem. Untreated maternal depression has multiple potential negative effects on maternal-infant attachment and child development. Screening for depression in the perinatal period is feasible in multiple primary care or obstetric settings, and can help identify depressed mothers earlier. However, there are multiple barriers to appropriate treatment, including concerns about medication effects in breastfeeding infants. This article reviews the literature and recommendations for the treatment of postpartum depression, with a focus on the range of pharmacological, psychotherapeutic, and other non-pharmacologic interventions. Keywords: postpartum depression, postnatal depression, lactation, antidepressant, hormone therapy, psychotherapy, bright light therapy, omega-3

  17. "'Jackin’ for Beats'": DJing for Citation Critique

    Directory of Open Access Journals (Sweden)

    Todd Craig

    2013-10-01

    Full Text Available A challenge in teaching English composition is helping students envision plagiarism as “borrowing” – showing love to author(s and/or text(s that further their argument(s, versus “stealing” – biting someone’s style and words. Alastair Pennycook (1996 and Sarah Wakefield (2006 have contributed pieces to the elaborate plagiarism/citation puzzle, while Houston Baker situated the hip-hop DJ in seminal text Black Studies, Rap and the Academy (1993. Merging these moments introduces critical questions: Did Diddy invent “the remix” or become the illest beat-biter ever? How did DJ/Producers Pete Rock and Large Professor pay homage to previous musical genres to further hip-hop remix production without just taking 4-8 bar samples, copying sources and claiming unethical ownership? And how can this discussion provide students a window into citation conversations? This article will remix these “texts” to introduce the idea of DJ Rhetoric to discuss plagiarism. Through the lens of the hip-hop DJ in writing classrooms, one can foster an appreciation of the difference between “love and theft” in student citation. This article will couple examples from hip-hop music/culture while simultaneously remixing interviews from various hip-hop DJ/producers to help answer these difficult questions.

  18. Hemolytic disease of the fetus and newborn caused by an antibody to a low-prevalence antigen, anti-SARA.

    Science.gov (United States)

    Towns, Dale; Hannon, Judith; Hendry, Julia; Barnes, Janet; Goldman, Mindy

    2011-09-01

    The first case describing the SARAH (SARA) antigen occurred in 1990, in an Australian blood donor. Hemolytic disease of the fetus and newborn (HDFN) due to anti-SARA has not been previously described. We report a case of HDFN in a multiparous female. The pregnancy was unremarkable except that she was involved in a seemingly minor motor vehicle accident at 25 weeks' gestation. Routine prenatal antibody screening was negative throughout the pregnancy. She presented at 37 weeks' gestation because of decreased fetal movements. Labor was induced and a 2702-g infant male was delivered. The infant's hemoglobin was 49 g/L and the bilirubin was 153 µmol/L. Blood samples from the parents and infant were referred to Canadian Blood Services National Immunohematology Reference Laboratory and subsequently to the Australian Red Cross Red Cell Reference Service. The father's and infant's red blood cells were confirmed to be SARA positive, and the mother's plasma contained anti-SARA. The infant was successfully treated with a double-volume exchange transfusion. This is the first example of HDFN associated with this antibody. © 2011 American Association of Blood Banks.

  19. Adolescent mental health: Challenges with maternal noncompliance

    Directory of Open Access Journals (Sweden)

    Vicki A Nejtek

    2010-03-01

    Full Text Available Vicki A Nejtek, Sarah Hardy, Scott WinterUniversity of North Texas Health Science Center, Fort Worth, TX, USAAbstract: The leading cause of suicide ideation, attempts, and completion in adolescents is persistent and unresolved parental conflict. National statistics show extremely high rates of childhood neglect and abuse are perpetrated most often by single mothers. Psychiatric disorders arising from maternal–child dysfunction are well-documented. However, resources to prevent offspring victimization are lacking. Here, we report maternal neglect of a 15-year-old male brought to the psychiatric emergency room for suicidal ideation. An inpatient treatment plan including pharmacotherapy, family therapy and psychological testing was initiated. The patient’s mother failed to attend clinic appointments or family therapy sessions. Clinician attempts to engage the mother in the treatment plan was met with verbal assaults, aggression, and threatening behavior. The patient decompensated in relation to the mother’s actions. Child Protective Services were contacted and a follow-up assessment with the patient and mother is pending. Psychiatric treatment of the mother may be a necessary intervention and prevention regimen for both the adolescent and the mother. Without consistent Child Protective Services oversight, medical and psychosocial follow-up, the prognosis and quality of life for this adolescent is considered very poor. Stringent mental health law and institutional policies are needed to adequately intercede and protect adolescents with mental illness.Keywords: adolescent, suicide, maternal treatment noncompliance, maternal neglect

  20. Psychos’ Haunting Memories: A(n (Uncommon Literary Heritage

    Directory of Open Access Journals (Sweden)

    Maria Antónia Lima

    2015-07-01

    Full Text Available In our times, one of the most prevailing forms of terror is certainly the psychological terror. In the history of literature and cinema, it’s impossible to forget some very widely known characters called psychos, especially those created by Edgar Allan Poe, Robert Bloch, Stephen King, Bret Easton Ellis, Sarah Kane and Patrick McGrath. Usually, they are haunted not only by their own private memories, but also by a literary memory that associates them to a common heritage, as if each psychotic character belonged to a very old gothic family, in which every member had been cursed to inherit the disease of his ancestors or the sins of his fathers. Haunted by images of their past, that recurrently return to the present, these psychos defy the barriers of time and all the traditional distinctions between reality and imagination, because one can never be sure if the stories are really about murders or about victims of their very diseased minds. Uncertainties and doubts disturb the reader as they also disturb the main character in search of a lost identity. Keywords: Psychos, Terror, Haunting Memories, Literary Heritage, Poe.

  1. IDEAS (Integrate, Design, Assess, and Share): A Framework and Toolkit of Strategies for the Development of More Effective Digital Interventions to Change Health Behavior.

    Science.gov (United States)

    Mummah, Sarah Ann; Robinson, Thomas N; King, Abby C; Gardner, Christopher D; Sutton, Stephen

    2016-12-16

    Developing effective digital interventions to change health behavior has been a challenging goal for academics and industry players alike. Guiding intervention design using the best combination of approaches available is necessary if effective technologies are to be developed. Behavioral theory, design thinking, user-centered design, rigorous evaluation, and dissemination each have widely acknowledged merits in their application to digital health interventions. This paper introduces IDEAS, a step-by-step process for integrating these approaches to guide the development and evaluation of more effective digital interventions. IDEAS is comprised of 10 phases (empathize, specify, ground, ideate, prototype, gather, build, pilot, evaluate, and share), grouped into 4 overarching stages: Integrate, Design, Assess, and Share (IDEAS). Each of these phases is described and a summary of theory-based behavioral strategies that may inform intervention design is provided. The IDEAS framework strives to provide sufficient detail without being overly prescriptive so that it may be useful and readily applied by both investigators and industry partners in the development of their own mHealth, eHealth, and other digital health behavior change interventions. ©Sarah Ann Mummah, Thomas N Robinson, Abby C King, Christopher D Gardner, Stephen Sutton. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 16.12.2016.

  2. Cine club

    CERN Document Server

    Cine club

    2017-01-01

    Wednesday 1st March 2017 at 20:00 CERN Council Chamber Fish Tank Directed by Andrea Arnold UK, 2009, 123 minutes Mia, an aggressive fifteen-year-old girl, lives on an Essex estate with her tarty mother, Joanne, and precocious little sister Tyler. She has been thrown out of school and is awaiting admission to a referrals unit and spends her days aimlessly. She begins an uneasy friendship with Joanne's slick boyfriend, Connor, who encourages her one interest, dancing. Original version English; French subtitles In collaboration with the Women In Technology Community Wednesday 8 March 2017 at 20:00 CERN Council Chamber Suffragette Directed by Sarah Gavron UK, 2015, 106 minutes A drama that tracks the story of the foot soldiers of the early feminist movement, women who were forced underground to pursue a dangerous game of cat and mouse with an increasingly brutal State. These were primarily working-class women who had seen peaceful protest achieve nothing. Turning to violence as the only route to chan...

  3. Social Semantics for an Effective Enterprise

    Science.gov (United States)

    Berndt, Sarah; Doane, Mike

    2012-01-01

    An evolution of the Semantic Web, the Social Semantic Web (s2w), facilitates knowledge sharing with "useful information based on human contributions, which gets better as more people participate." The s2w reaches beyond the search box to move us from a collection of hyperlinked facts, to meaningful, real time context. When focused through the lens of Enterprise Search, the Social Semantic Web facilitates the fluid transition of meaningful business information from the source to the user. It is the confluence of human thought and computer processing structured with the iterative application of taxonomies, folksonomies, ontologies, and metadata schemas. The importance and nuances of human interaction are often deemphasized when focusing on automatic generation of semantic markup, which results in dissatisfied users and unrealized return on investment. Users consistently qualify the value of information sets through the act of selection, making them the de facto stakeholders of the Social Semantic Web. Employers are the ultimate beneficiaries of s2w utilization with a better informed, more decisive workforce; one not achieved with an IT miracle technology, but by improved human-computer interactions. Johnson Space Center Taxonomist Sarah Berndt and Mike Doane, principal owner of Term Management, LLC discuss the planning, development, and maintenance stages for components of a semantic system while emphasizing the necessity of a Social Semantic Web for the Enterprise. Identification of risks and variables associated with layering the successful implementation of a semantic system are also modeled.

  4. Serological prevalence of celiac disease in Brazilian population of multiple sclerosis, neuromyelitis optica and myelitis.

    Science.gov (United States)

    de Oliveira, Pérola; de Carvalho, Daniel Rocha; Brandi, Ivar Viana; Pratesi, Riccardo

    2016-09-01

    Comorbidity of celiac disease with demyelinating diseases of the central nervous system has been reported since the 1960s. The objective of this study was to determine the serological prevalence of celiac disease in the largest series of patients diagnosed with multiple sclerosis, neuromyelitis optica, or myelitis. A prevalence study was conducted with patients evaluated at Sarah Network of Rehabilitation Hospitals between March 2012 and September 2013. They were previously diagnosed with multiple sclerosis, neuromyelitis optica, or idiopathic myelitis. The serum levels of antibodies against tissue transglutaminase and endomysium were assessed. Of the 379 patients evaluated, 249 (65.70%) were diagnosed with multiple sclerosis, 37 (9.56%) with neuromyelitis optica, and 96 (24.54%) with idiopathic myelitis. Two patients (0.53%), one with multiple sclerosis and other with myelitis, tested positive for both antibodies. Our study do not confirm the relationship between celiac serological antibodies with multiple sclerosis, neuromyelitis optica and inflammatory myelitis of an unknown etiology. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. FlexibleSUSY-A spectrum generator generator for supersymmetric models

    Science.gov (United States)

    Athron, Peter; Park, Jae-hyeon; Stöckinger, Dominik; Voigt, Alexander

    2015-05-01

    We introduce FlexibleSUSY, a Mathematica and C++ package, which generates a fast, precise C++ spectrum generator for any SUSY model specified by the user. The generated code is designed with both speed and modularity in mind, making it easy to adapt and extend with new features. The model is specified by supplying the superpotential, gauge structure and particle content in a SARAH model file; specific boundary conditions e.g. at the GUT, weak or intermediate scales are defined in a separate FlexibleSUSY model file. From these model files, FlexibleSUSY generates C++ code for self-energies, tadpole corrections, renormalization group equations (RGEs) and electroweak symmetry breaking (EWSB) conditions and combines them with numerical routines for solving the RGEs and EWSB conditions simultaneously. The resulting spectrum generator is then able to solve for the spectrum of the model, including loop-corrected pole masses, consistent with user specified boundary conditions. The modular structure of the generated code allows for individual components to be replaced with an alternative if available. FlexibleSUSY has been carefully designed to grow as alternative solvers and calculators are added. Predefined models include the MSSM, NMSSM, E6SSM, USSM, R-symmetric models and models with right-handed neutrinos.

  6. `Pd20Sn13' revisited: crystal structure of Pd6.69Sn4.31

    Directory of Open Access Journals (Sweden)

    Wilhelm Klein

    2015-07-01

    Full Text Available The crystal structure of the title compound was previously reported with composition `Pd20Sn13' [Sarah et al. (1981. Z. Metallkd, 72, 517–520]. For the original structure model, as determined from powder X-ray data, atomic coordinates from the isostructural compound Ni13Ga3Ge6 were transferred. The present structure determination, resulting in a composition Pd6.69Sn4.31, is based on single crystal X-ray data and includes anisotropic displacement parameters for all atoms as well as standard uncertainties for the atomic coordinates, leading to higher precision and accuracy for the structure model. Single crystals of the title compound were obtained via a solid-state reaction route, starting from the elements. The crystal structure can be derived from the AlB2 type of structure after removing one eighth of the atoms at the boron positions and shifting adjacent atoms in the same layer in the direction of the voids. One atomic site is partially occupied by both elements with a Pd:Sn ratio of 0.38 (3:0.62 (3. One Sn and three Pd atoms are located on special positions with site symmetry 2. (Wyckoff letter 3a and 3b.

  7. International Conference on Recent Trends in Physics 2016 (ICRTP2016)

    International Nuclear Information System (INIS)

    2016-01-01

    The ICRTP conference series, a bi-annual affair, has been hosted by School of Physics, Devi Ahilya University, Indore - 452001 (India), since 2012. The third such conference in this series ICRTP2016 was held during 13 - 14 February 2016. The purpose of the conference was to provide a platform that would enable scientists, teachers, researchers and students to interact and share ideas, thoughts and scientific findings in all areas of Physics, including Condensed matter and Materials Physics, Laser and Plasma Physics, Nuclear Physics, Computational Physics, High Energy Physics. Over 160 participants from India, Italy, Portugal and, Spain attended the conference that included an inaugural talk, a special talk, 16 invited talks, 3 oral presentations and, a poster session. Presented posters were judged by a panel of experts and, 3 best posters were awarded cash prize. We extend our heartfelt appreciation to all the conference committee members and, reviewers for their valuable time in making this conference a great success. We thank all the participants for making ICRTP 2016 an unforgettable event. Special thanks to Ms. Madhuri Shah for providing editorial assistance. Financial support from University Grants Commission (UGC), New Delhi, India is gratefully acknowledged. Sincere thanks to university administration, faculty members, administrative staff volunteers and, students of the School of Physics for their support in organizing ICRTP 2016. Thanks are due to Ms Sarah Toms, Conference Publishing Coordinator, Journal of Physics Conference Series (JPCS), IOP Publishing Ltd, UK, for all help in bringing out ICRTP 2016 proceedings in JPCS. (paper)

  8. The role of the NLRP3 inflammasome in gout

    Directory of Open Access Journals (Sweden)

    Sarah R Kingsbury

    2011-03-01

    Full Text Available Sarah R Kingsbury1,2, Philip G Conaghan1,2, Michael F McDermott1,21Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine 2NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UKAbstract: Gout is an inflammatory arthritis characterized by abrupt self-limiting attacks of inflammation caused by precipitation of monosodium urate crystals (MSU in the joint. Recent studies suggest that orchestration of the MSU-induced inflammatory response is dependent on the proinflammatory cytokine IL-1ß, underlined by promising results in early IL-1 inhibitor trials in gout patients. This IL-1-dependent innate inflammatory phenotype, which is observed in a number of diseases in addition to gout, is now understood to rely on the formation of the macromolecular NLRP3 inflammasome complex in response to the MSU 'danger signal'. This review focuses on our current understanding of the NLRP3 inflammasome and its critical role in MSU-crystal induced inflammatory gout attacks. It also discusses the management of treatment-resistant acute and chronic tophaceous gout with IL-1 inhibitors; early clinical studies of rilonacept (IL-1 Trap, canakinumab (monoclonal anti-IL-1ß antibody, and anakinra have all demonstrated treatment efficacy in such patients.Keywords: gout, inflammasome, NLRP3, IL-1

  9. Adorno, Obama, and Empire: Reflections on the U.S. Presidential Election and the Next President

    Directory of Open Access Journals (Sweden)

    Lukas Kaelin

    2008-12-01

    Full Text Available As tempting as it might be, politics is a difficult field for philosophers.Well known are Plato’s and Heidegger’s attempt to influence the political developments of their time, which went badly wrong. Much safer is it to provide an interpretation of current political events, which is the aim of this paper. The paper attempts to philosophically assess the recent U.S. presidential race and to look at some aspects of the underlying beliefs of Barack Obama that aided him in his campaign. The philosophical framework used in order to interpret the political events are mainly from the Critical Theory of Theodor W. Adorno and the neo-Marxist approach of Michael Hardt and Antonio Negri. Further observations will concentrate on the logic and attraction of the electoral process and the dialectical logic of Sarah Palin’s statements. The first part will discuss the form of U.S. electoral politics, especially the perpetual campaign, whereas the second part will put the policiesof the next U.S. president into a philosophical context.

  10. Environmental political targets of the EU: German-French contributions for the achievement of the EU goals. Proceedings; Umweltpolitische Ziele der EU: Deutsch-franzoesische Beitraege zur Zielerreichung. Concepts franco-allemands pour atteindre les objectifs environnementaux de l'UE. Tagungsband. Actes

    Energy Technology Data Exchange (ETDEWEB)

    Cail, Sylvain; Moest, Dominik; Fichtner, Wolf; Percebois, Jacques (eds.)

    2009-07-01

    The first German-French workshop on energy economy and sustainability on January 29 and 30, 2009 at Karlsruhe (Federal Republic of Germany) comprised the following lectures: (1) Systematic evaluation of the sustainability in energy projects (Volker Stelzer); (2) Comparative value of various mechanisms of promoting renewable energy sources (Jacques Percebois, Olivier Rousse); (3) Communities as actors in climate protection (Lioba Markl, Nurten Avci); (4) The chain of value of photovoltaic systems containing crystalline silicon (Christin Oeser); (5) The wind power industry as an example of the German-French cooperation for the achievement of environmental political targets of the EU (Katharina Braig, Markus Jenne); (6) A short history of the future of biomass and biofuels in relation to white biotechnologies (Gerard Goma, Carole Molina-Jouve); (7) Generation and feeding of methane from biomass (Frank Graf); (8) Energy evaluation of the thickening of the biomass by rapid pyrolysis (Guillain Mauviel et al.); (9) Future role of renewable energies in European electricity supply (Dominik Moest et al.); (10) A systematic evaluation of the potentials for reducing CO{sub 2} as an element of company management (Sarah Schwarz); (11) A system dynamics model of the German electricity market (Tobias Jaeger).

  11. Brick Lane Patchwork

    Directory of Open Access Journals (Sweden)

    Emanuele Monegato

    2009-12-01

    Full Text Available The essay Brick Lane Patchwork takes its roots in the consideration that the most effective cultural representations of London Brick Lane are explicitly or implicitly linked to the nature of a patchwork. Many contemporary cultural representations made a vain and ambitious effort to portray the real soul(s of Brick Lane, without taking into consideration its complexity and, therefore, delivering a distinctive image of the area as if it was a single piece of cloth, not a whole quilt. Starting from already existing cultural representations of Brick Lane (Monica Ali's first novel Brick Lane and its filmic adaptation directed by Sarah Gavron, the poetic memoir Salaam Brick Lane - a Year in the New East End and the short film Brick Lane by Paul Makkar, which are going to be privileged squared cloths to be sewn in the above mentioned patchwork, the aim of this essay is both to detect its proper cultural representations and to sew an imaginative patchwork quilt, a new and multiple image of this London area enhancing its hybrid soul(s, its blending procedure and contemporary facets. Ali M., 2004, Brick Lane, Doubleday Black Swan, London.Gavron S., 2007, Brick Lane, Sony Pictures Classics.Hall T., 2005, Salaam Brick Lane - A Year in the New East End, John Murray Publishers, London. Makkar P., 2002, Brick Lane, Anapurna Films.

  12. The principle of procreative beneficence: old arguments and a new challenge.

    Science.gov (United States)

    Hotke, Andrew

    2014-06-01

    In the last ten years, there have been a number of attempts to refute Julian Savulescu's Principle of Procreative Beneficence; a principle which claims that parents have a moral obligation to have the best child that they can possibly have. So far, no arguments against this principle have succeeded at refuting it. This paper tries to explain the shortcomings of some of the more notable arguments against this principle. I attempt to break down the argument for the principle and in doing so, I explain what is needed to properly refute it. This helps me show how and why the arguments of Rebecca Bennett, Sarah Stoller and others fail to refute the principle. Afterwards, I offer a new challenge to the principle. I attack what I understand to be a fundamental premise of the argument, a premise which has been overlooked in the literature written about this principle. I argue that there is no reason to suppose, as Savulescu does, that morality requires us to do what we have most reason to do. If we reject this premise, as I believe we have reason to do, the argument for Procreative Beneficence fails. © 2012 John Wiley & Sons Ltd.

  13. Schriftstellerinnen der DDR und feministisches Bewußtsein im Staatssozialismus

    Directory of Open Access Journals (Sweden)

    Eva Kaufmann

    2001-11-01

    Full Text Available Seit den 1960er Jahren produzierten Schriftstellerinnen in der DDR wie Christa Wolf, Irmtraud Morgner, Sarah Kirsch, Brigitte Reimann, Charlotte Worgitzky, Lia Pirskawetz, und Maya Wiens eine vielfältige Literatur zu frauenrelevanten Themen. Den Obertitel „The Promised Land“ (das gelobte Land hat Lorna Martens Irmtraud Morgner entlehnt, der Autorin, die sie neben Christa Wolf als wichtigste Zeugin für „feminist writing“ in der DDR betrachtet. In Morgners Roman Leben und Abenteuer der Trobadora Beatriz steht der Begriff „gelobtes Land“ bezogen auf die DDR in einem ironischen Zusammenhang. Mit simplem Jaja oder Neinnein ist diesem „Ort des Wunderbaren“ (Morgner nicht beizukommen. Vergleichbares signalisiert auch das Fragezeichen, das Martens hinter den Begriff „Promised Land“ setzt. Der anspielungsreiche Verweis auf das Land erscheint auch insofern nützlich, als die Eigenart feministischen Schreibens genauer zu fassen ist, wenn über das Land selbst, namentlich seine Frauenpolitik, Auskünfte gegeben werden. Lorna Martens möchte herausfinden, wie Schriftstellerinnen in der DDR feministisches Bewusstsein artikuliert haben, d.h. feministisches Bewusstsein unter den vom Staatssozialismus geschaffenen Bedingungen.

  14. A STUDY ABOUT PHYSICOCHEMICAL COMPOSITION OF FRESH AND LYOPHILIZED ROYAL JELLY

    Directory of Open Access Journals (Sweden)

    OLIMPIA POPESCU

    2008-10-01

    Full Text Available This paper contents a summery about physicochemical composition of frash and lyophilized royal jelly. Royal jelly (RJ is a yellowish and creamy secretion from hypo pharyngeal and mandibular glands of young worker bees (Apis mellifera L. to feed all larvae for the first three days of their life and the queen bee for both her larval life and adulthood.. Royal jelly is a honey bee secretion that is used in the nutrition of the larvae. Queen bees are made, not born, and their feeding with royal jelly is the key to that process. The geographical authenticity of royal jelly can be determined also by pollen analysis (Ricciardelli d'Albore et al., 1978; Ricciardelli d'Albore, 1986. The physicochemical composition of pure royal jelly are analyzed by determining moisture, ash, lipids, proteins, carbohydrates, 10-HDA; and for lyophilized royal jelly are analyzed by determining ash, lipids, protein, carbohydrates, 10-HDA, sugars. 10-HDA content is the criteria of royal jelly quality analysis and it is a freshness parameter(Antinelli J.F., Sarah Zeggane, Renee Davico, Catherine Rognone, Jean Paul Faucon, Louisette Lizzani.

  15. Interview with Dr. Charley Zeanah: (interviewed by Normand Carrey MD, Tulane University, New Orleans, January 9, 2013).

    Science.gov (United States)

    2013-05-01

    Dr. Charles Zeanah is the Mary K. Sellars-Polchow Chair in Psychiatry, Professor of Clinical Pediatrics and Vice Chair for Child and Adolescent Psychiatry in the Department of Psychiatry and Behavioral Sciences at Tulane University School of Medicine in New Orleans. He is also Executive Director of the Institute for Infant and Early Childhood Mental Health at Tulane. He is the recipient of multiple awards including the Irving Phillips Award for Prevention, (AACAP), the Presidential Citation for Distinguished Research and Leadership in Infant Mental Health (American Orthopsychiatric Association), the Sarah Haley Memorial Award for Clinical Excellence (International Society for Traumatic Stress Studies), the Blanche F. Ittelson Award for Research in Child Psychiatry (APA), and the Serge Lebovici Award for International Contributions in Infant Mental Health (World Association for Infant Mental Health). Dr. Zeanah is a Distinguished Fellow of AACAP, a Distinguished Fellow of the APA and a Board Member of Zero to Three. He is the Editor of Handbook of Infant Mental Health (3(rd) edition) considered as the state of the art textbook and standard reference in the field of Infant Mental Health.

  16. Club d'orientation

    CERN Multimedia

    Le Club d’Orientation du CERN

    2011-01-01

    La première course d’orientation comptant pour la Coupe Genevoise de printemps a eu lieu près de Cossonay samedi 19 mars ; une bonne soixantaine de coureurs avaient fait le déplacement. Les vainqueurs sont : technique long, Domenico Lepori (Care Vevey) s’imposant d’une minute devant Yannick Gagneret (O’Jura) ; technique moyen, Jean-Rodolphe Knuchel (CO Lausanne-Jorat) devant Cédric Wehrle (CO CERN) ; technique court, Marie Droz (ANCO) ; facile moyen, Elia Martarelli devant Konstantinos Haider (CO CERN); facile court, Sarah Stuber (CO Lausanne-Jorat). Prochain rendez-vous à noter : samedi 26 mars dans la forêt d’Attalens (Canton de Vaud), parking au terrain de foot. Les inscriptions et départs de la course populaire se feront entre 13h et 15h. Pour ceux qui ne connaissent pas l’orientation, c’est l&am...

  17. SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Sung Jun [Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, United States; Ni, Lisheng [Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, United States; Osinski, Adam [Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, United States; Tomchick, Diana R. [Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States; Brautigam, Chad A. [Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, United States; Luo, Xuelian [Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, United States; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, United States

    2017-10-24

    The Hippo pathway controls tissue growth and homeostasis through a central MST-LATS kinase cascade. The scaffold protein SAV1 promotes the activation of this kinase cascade, but the molecular mechanisms remain unknown. Here, we discover SAV1-mediated inhibition of the PP2A complex STRIPAKSLMAP as a key mechanism of MST1/2 activation. SLMAP binding to autophosphorylated MST2 linker recruits STRIPAK and promotes PP2A-mediated dephosphorylation of MST2 at the activation loop. Our structural and biochemical studies reveal that SAV1 and MST2 heterodimerize through their SARAH domains. Two SAV1–MST2 heterodimers further dimerize through SAV1 WW domains to form a heterotetramer, in which MST2 undergoes trans-autophosphorylation. SAV1 directly binds to STRIPAK and inhibits its phosphatase activity, protecting MST2 activation-loop phosphorylation. Genetic ablation of SLMAP in human cells leads to spontaneous activation of the Hippo pathway and alleviates the need for SAV1 in Hippo signaling. Thus, SAV1 promotes Hippo activation through counteracting the STRIPAKSLMAP PP2A phosphatase complex.

  18. The use of cognitive behavioral therapy in the treatment of resistant depression in adolescents

    Directory of Open Access Journals (Sweden)

    Prieto-Hicks X

    2012-09-01

    Full Text Available Sarah Hamill-Skoch,1 Paul Hicks,2 Ximena Prieto-Hicks11Department of Psychiatry, 2Department of Family and Community Medicine, University of Arizona, Tuscon, AZ, USAAbstract: Major depressive disorder often begins in adolescence, is chronic and recurrent, and heightens an individual's risk for major depressive disorder in adulthood. Treatment-resistant depression is a problem for a significant minority of adolescents. Few studies have examined treatments for treatment-resistant depression among adolescents, and even fewer have examined the use of cognitive-behavioral therapy as a monotherapy or in combination with pharmacological treatments. Mental health professionals have a strong interest in understanding what treatments are appropriate for adolescents who are treatment resistant. Preliminary evidence from current published trials indicates that the use of cognitive-behavioral therapy in combination with antidepressant medication yields the best outcome for treatment-resistant depression in adolescents. Secondary analyses also suggest that the utility of cognitive behavioral therapy can be increased by ensuring adolescents receive a therapeutic dose of treatment sessions (more than nine sessions and the inclusion of two treatment components: social skills and problem solving training. Guidelines for clinicians as well as areas for future research are discussed.Keywords: cognitive behavior therapy, treatment-resistant depression, adolescent depression

  19. Tattoo removal with ingenol mebutate

    Directory of Open Access Journals (Sweden)

    Cozzi SJ

    2017-05-01

    Full Text Available Sarah-Jane Cozzi,1 Thuy T Le,1 Steven M Ogbourne,2 Cini James,1 Andreas Suhrbier1 1Inflammation Biology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, 2Genecology Research Center, Faculty of Science, Health, Engineering and Education, University of the Sunshine Coast, Maroochydore DC, QLD, Australia Abstract: An increasing number of people are getting tattoos; however, many regret the decision and seek their removal. Lasers are currently the most commonly used method for tattoo removal; however, treatment can be lengthy, costly, and sometimes ineffective, especially for certain colors. Ingenol mebutate is a licensed topical treatment for actinic keratoses. Here, we demonstrate that two applications of 0.1% ingenol mebutate can efficiently and consistently remove 2-week-old tattoos from SKH/hr hairless mice. Treatment was associated with relocation of tattoo microspheres from the dermis into the posttreatment eschar. The skin lesion resolved about 20 days after treatment initiation, with some cicatrix formation evident. The implications for using ingenol mebutate for tattoo removal in humans are discussed. Keywords: tattoo, ingenol mebutate, mouse 

  20. Education and certification of genetic counselors.

    Science.gov (United States)

    Katsichti, L; Hadzipetros-Bardanis, M; Bartsocas, C S

    1999-01-01

    Genetic counseling is defined by the American Society of Human Genetics as a communication process which deals with the human problems associated with the occurrence, or risk of occurrence, of a genetic disorder in a family. The first graduate program (Master's degree) in genetic counseling started in 1969 at Sarah Lawrence College, NY, USA, while in 1979 the National Society of Genetic Counseling (NSGC) was established. Today, there are 29 programs in U.S.A. offering a Master's degree in Genetic Counseling, five programs in Canada, one in Mexico, one in England and one in S. Africa. Most of these graduate programs offer two year training, consisting of graduate courses, seminars, research and practical training. Emphasis is given in human physiology, biochemistry, clinical genetics, cytogenetics, molecular and biochemical genetics, population genetics and statistics, prenatal diagnosis, teratology and genetic counseling in relation to psychosocial and ethical issues. Certification for eligible candidates is available through the American Board of Medical Genetics (ABMG). Requirements for certification include a master's degree in human genetics, training at sites accredited by the ABMG, documentation of genetic counseling experience, evidence of continuing education and successful completion of a comprehensive ABMG certification examination. As professionals, genetic counselors should maintain expertise, should insure mechanisms for professional advancement and should always maintain the ability to approach their patients.

  1. Challenges and Opportunities of Big Data in Health Care: A Systematic Review.

    Science.gov (United States)

    Kruse, Clemens Scott; Goswamy, Rishi; Raval, Yesha; Marawi, Sarah

    2016-11-21

    Big data analytics offers promise in many business sectors, and health care is looking at big data to provide answers to many age-related issues, particularly dementia and chronic disease management. The purpose of this review was to summarize the challenges faced by big data analytics and the opportunities that big data opens in health care. A total of 3 searches were performed for publications between January 1, 2010 and January 1, 2016 (PubMed/MEDLINE, CINAHL, and Google Scholar), and an assessment was made on content germane to big data in health care. From the results of the searches in research databases and Google Scholar (N=28), the authors summarized content and identified 9 and 14 themes under the categories Challenges and Opportunities, respectively. We rank-ordered and analyzed the themes based on the frequency of occurrence. The top challenges were issues of data structure, security, data standardization, storage and transfers, and managerial skills such as data governance. The top opportunities revealed were quality improvement, population management and health, early detection of disease, data quality, structure, and accessibility, improved decision making, and cost reduction. Big data analytics has the potential for positive impact and global implications; however, it must overcome some legitimate obstacles. ©Clemens Scott Kruse, Rishi Goswamy, Yesha Raval, Sarah Marawi. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 21.11.2016.

  2. At the margins of biomedicine: the ambiguous position of 'Registered Medical Practitioners' in rural Indian healthcare.

    Science.gov (United States)

    Nahar, Papreen; Kannuri, Nanda Kishore; Mikkilineni, Sitamma; Murthy, G V S; Phillimore, Peter

    2017-05-01

    This analysis challenges a tendency in public health and the social sciences to associate India's medical pluralism with a distinction between biomedicine, as a homogeneous entity, and its non-biomedical 'others'. We argue that this overdrawn dichotomy obscures the important part played by 'informal' biomedical practice, an issue with salience well beyond India. Based on a qualitative study in rural Andhra Pradesh, South India, we focus on a figure little discussed in the academic literature - the Registered Medical Practitioner (RMP) - who occupies a niche in the medical market-place as an informal exponent of biomedical treatment. We explore the significance of these practitioners by tracking diagnosis and treatment of one increasingly prominent medical 'condition', namely diabetes. The RMP, who despite the title is rarely registered, sheds light on the supposed formal-informal sector divide in India's healthcare system, and its permeability in practice. We develop our analysis by contrasting two distinctive conceptualisations of 'informality' in relation to the state in India - one Sarah Pinto's, the other Ananya Roy's. © 2016 The Authors. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL.

  3. A Proton Flare Triggered the Mw 8.1 Chiapos Mexican Earthquake

    Science.gov (United States)

    Elfaki, H.; Yousef, S.

    2017-12-01

    In a 2015 Cairo University M.Sc. thesis by Sarah Khodairy, very strong earthquakes were found to be highly correlated with proton flares. Strange blue and green bright flashes of light across Mexico accompanied the 8th of September 2017 Mw 1.8 Chiapas earthquake. Those lights were contemporary with a solar proton flare. Those green and blue lights are indicative of the arrival of proton streams over Mexico and their interaction with atmospheric Oxygen and Nitrogen atoms respectively in analogy with aurora lights. The proton streams attacked the weak spots of tectonic plates where the Coscos plate is being subducted below the North American plate. It is suggested that they induced telluric electric currents in the ground and in the magma thus caused motion and more subduction in the tectonic plates. Such motion immediately trigged the Chiapas earthquake in the near vicinity. The Bz component of the interplanetary magnetic field was highly negative, a door was opened in the magnetosphere and the proton stream easily leaked inside and targeted Mexico. This proton flare was accompanied by coronal mass ejection and extremely strong X.9.3- class X-ray flare as well as magnetic storms. On the other hand, the 19th of September Mw 7.1 Puebla central Mexico earthquake was initiated by fast solar wind coronal hole stream. Such stream if they hit ground they cause earthquakes, if they hit narrow seas like the Red Sea they cause flash floods. However if they target Oceans they initiate hurricanes.

  4. "How to stop choking to death": Rethinking lesbian separatism as a vibrant political theory and feminist practice.

    Science.gov (United States)

    Enszer, Julie R

    2016-01-01

    In contemporary feminist discourses, lesbian separatism is often mocked. Whether blamed as a central reason for feminism's alleged failure or seen as an unrealistic, utopian vision, lesbian separatism is a maligned social and cultural formation. This article traces the intellectual roots of lesbian feminism from the early 1970s in The Furies and Radicalesbians through the work of Julia Penelope and Sarah Lucia Hoagland in the 1980s and 1990s, then considers four feminist and lesbian organizations that offer innovative engagements with lesbian separatism. Olivia Records operated as a separatist enterprise, producing and distributing womyn's music during the 1970s and 1980s. Two book distributors, Women in Distribution, which operated in the 1970s, and Diaspora Distribution, which operated in the 1980s, offer another approach to lesbian separatism as a form of economic and entrepreneurial engagement. Finally, Sinister Wisdom, a lesbian-feminist literary and arts journal, enacts a number of different forms of lesbian separatism during its forty-year history. These four examples demonstrate economic and cultural investments of lesbian separatism and situate its investments in larger visionary feminist projects. More than a rigid ideology, lesbian separatism operates as a feminist process, a method for living in the world.

  5. β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model

    Directory of Open Access Journals (Sweden)

    Zigmond E

    2014-10-01

    Full Text Available Ehud Zigmond,1,* Oshrat Tayer-Shifman,1,* Gadi Lalazar,1 Ami Ben Ya'acov,1 Sarah Weksler-Zangen,2 David Shasha,1 Miriam Sklair-Levy,3 Lidya Zolotarov,1 Zvi Shalev,1 Rony Kalman,2 Ehud Ziv,2 Itamar Raz,2 Yaron Ilan1 1Liver Unit, 2Diabetes Unit, 3Department of Radiology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel *These authors contributed equally to this workAbstract: Liver steatosis is a common characteristic of obesity and type 2 diabetes, and fatty liver disease is increasingly recognized as a major health burden. Accumulating evidence suggests that β-glycosphingolipids play an important role in insulin sensitivity and thus could affect hepatic steatosis. To determine the effect associated with β-glycosphingolipid-mediated amelioration of liver injury, seven groups of Psammomys obesus on a high-energy diet were studied. Animals were treated with daily injections of β-glucosylceramide, β-lactosylceramide, or a combination of both. β-glycosphingolipids ameliorated the hepatic injury manifested by decreased liver enzymes, liver weight, and hepatic fat, and improved liver histology. Administration of both β-glucosylceramide and β-lactosylceramide also decreased interferon (IFN-γ serum levels. These effects were associated with improved serum cholesterol and triglyceride levels. These data suggest that β-glycosphingolipids ameliorate liver injury in an animal model of nonalcoholic steatohepatitis.Keywords: NAFLD, glycolipids, STAT, NASH, insulin resistance, diabetes

  6. Intervention in health care teams and working relationships

    Directory of Open Access Journals (Sweden)

    Laurenson M

    2012-09-01

    Full Text Available Mary Laurenson, Tracey Heath, Sarah GribbinUniversity of Hull, Faculty of Health and Social Care, Department of Health Professional Studies, Cottingham, Hull, United KingdomIntroduction: Communication is an intrinsic part of collaborative working but can be problematic when the complexities of professional and personal identities inhibit quality care provision. This paper investigates these complexities and recommends interventions to facilitate collaborative working.Methods: A qualitative comparative approach examined data collected from participants using purposive non-probability sampling. Perspectives were obtained from four professional groups (nurses, social workers, care managers, and police, from different organizations with different theoretical and practice frameworks, and from a fifth group (informal carers.Results: Curriculum change and leadership initiatives are required to address the complexities inhibiting collaborative working relationships. Integrating complexity theory, personality typology, and problem-based learning into the curriculum to understand behavioral actions will enable interventions to effect change and promote the centrality of those being cared for.Keywords: interprofessional education and working, complexity, communication, personality, problem-based learning

  7. Transient loading of CD34+ hematopoietic progenitor cells with polystyrene nanoparticles

    Directory of Open Access Journals (Sweden)

    Deville S

    2017-01-01

    Full Text Available Sarah Deville,1,2 Wahyu Wijaya Hadiwikarta,1 Nick Smisdom,1,2 Bart Wathiong,1,3 Marcel Ameloot,2 Inge Nelissen,1 Jef Hooyberghs1,3 1VITO, Flemish Institute for Technological Research, Mol, Belgium; 2Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium; 3Theoretical Physics, Hasselt University, Diepenbeek, Belgium Abstract: CD34+ hematopoietic progenitor cells (HPCs offer great opportunities to develop new treatments for numerous malignant and non-malignant diseases. Nanoparticle (NP-based strategies can further enhance this potential, and therefore a thorough understanding of the loading behavior of HPCs towards NPs is essential for a successful application. The present study focusses on the interaction kinetics of 40 nm sized carboxylated polystyrene (PS NPs with HPCs. Interestingly, a transient association of the NPs with HPCs is observed, reaching a maximum within 1 hour and declining afterwards. This behavior is not seen in dendritic cells (CD34-DCs differentiated from HPCs, which display a monotonic increase in NP load. We demonstrate that this transient interaction requires an energy-dependent cellular process, suggesting active loading and release of NPs by HPCs. This novel observation offers a unique approach to transiently equip HPCs. A simple theoretical approach modeling the kinetics of NP loading and release is presented, contributing to a framework of describing this phenomenon. Keywords: nanoparticles, hematopoietic progenitor cells, dendritic cells, uptake, release

  8. Paul Gauguin and the origin of Art Noveau

    Science.gov (United States)

    Asmus, John F.

    1997-10-01

    Since the turn of the century there has been widespread acknowledgement that Alphonse Mucha inspired the birth of the Art Nouveau movement when he created the 'Gismonda' poster advertising the opening of the Sarah Bernhardt play of that name in Paris in 1894. At an estate sale in 1954 a small collage bearing a likeness of the Mucha 'Gismonda' was offered. It was composed of fragments of sixty postage stamps glued to a small ceramic tile. Digital computer image processing has been applied to the collage design, scratches on the handle of a walking stick in the same collection, and the Mucha poster. From comparative analyses of the enhanced 'Gismonda' images it is revealed that the little collage is considerably more detailed and compete than the Mucha 'original'. Thus, it is concluded that the poster is a hasty photographic plagiarism of the intricate collage. Further image processing of the scratches on the handle of the walking stick and the collage reveal them to conform to the famous and enigmatic 'P GO' monogram signature of the artist Paul Gauguin. Thus, it follows that the original design was created by Gauguin rather than by Mucha. It may be that while Gauguin was in Brittany recovering from injuries sustained in a brawl his former lover, Annah la Javanese, pilfered his belongings and took them with her to Paris and her next lover, photographer-designer, Alphonse Mucha, who copied the collage and offered it as the Gismonda Poster.

  9. Paul Gauguin in Brittany

    Science.gov (United States)

    Asmus, John F.

    2009-07-01

    Ever since the dawn of the 20th Century there has been a universal consensus that Alphonse Mucha launched the sensation that became known as Art Nouveau. This event was associated with the appearance of his Gismonda poster promoting the Sarah Bernhardt play of that name in Paris in 1894. At an estate sale in 1954 a small collage bearing a likeness of Mucha's Gismonda was offered. It had been fabricated by gluing slivers cut from sixty postage stamps to a 20cm ceramic tile. Digital computer image enhancement was applied to the collage design, initials on a walking stick from the same estate collection, and the Mucha poster. These geometrical analyses revealed that the collage is more detailed than the Mucha "original". This led to our hypothesis that the famous poster was a hasty photographic plagiarism of the intricate ceramic-tile collage. Image analyses of the initials on the companion walking stick revealed conformity with the famous enigmatic "P GO" monogram of Paul Gauguin. We conclude that Gauguin rather than Mucha created the Gismonda composition. Historical evidence suggests that, while Gauguin was in Brittany recovering from injuries sustained in a fistfight, Annah la Javanese stole his possessions and took them to Paris where her next lover, Mucha, copied the collage and presented it as his original poster design.

  10. Intrauterine hypoxia: clinical consequences and therapeutic perspectives

    Directory of Open Access Journals (Sweden)

    Thompson LP

    2015-09-01

    Full Text Available Loren P Thompson,1 Sarah Crimmins,1 Bhanu P Telugu,2 Shifa Turan1 1Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; 2Department of Animal Sciences, University of Maryland, College Park, MD, USA Abstract: Intrauterine hypoxia is a significant clinical challenge in obstetrics that affects both the pregnant mother and fetus. Intrauterine hypoxia can occur in pregnant women living at high altitude and/or with cardiovascular disease. In addition, placental hypoxia can be generated by altered placental development and spiral artery remodeling leading to placental insufficiency and dysfunction. Both conditions can impact normal maternal cardiovascular homeostasis leading to preeclampsia and/or impair transfer of O2/nutrient supply resulting in fetal growth restriction. This review discusses the mechanisms underlying altered placental vessel remodeling, maternal and fetal consequences, patient management, and potential future therapies for improving these conditions. Keywords: fetal growth restriction, oxidative stress, extravillous trophoblast invasion, Doppler ultrasound, pulsatility index, preeclampsia 

  11. The hazards of correcting myths about health care reform.

    Science.gov (United States)

    Nyhan, Brendan; Reifler, Jason; Ubel, Peter A

    2013-02-01

    Misperceptions are a major problem in debates about health care reform and other controversial health issues. We conducted an experiment to determine if more aggressive media fact-checking could correct the false belief that the Affordable Care Act would create "death panels." Participants from an opt-in Internet panel were randomly assigned to either a control group in which they read an article on Sarah Palin's claims about "death panels" or an intervention group in which the article also contained corrective information refuting Palin. The correction reduced belief in death panels and strong opposition to the reform bill among those who view Palin unfavorably and those who view her favorably but have low political knowledge. However, it backfired among politically knowledgeable Palin supporters, who were more likely to believe in death panels and to strongly oppose reform if they received the correction. These results underscore the difficulty of reducing misperceptions about health care reform among individuals with the motivation and sophistication to reject corrective information.

  12. Setting clear expectations for safety basis development

    International Nuclear Information System (INIS)

    MORENO, M.R.

    2003-01-01

    DOE-RL has set clear expectations for a cost-effective approach for achieving compliance with the Nuclear Safety Management requirements (10 CFR 830, Nuclear Safety Rule) which will ensure long-term benefit to Hanford. To facilitate implementation of these expectations, tools were developed to streamline and standardize safety analysis and safety document development resulting in a shorter and more predictable DOE approval cycle. A Hanford Safety Analysis and Risk Assessment Handbook (SARAH) was issued to standardized methodologies for development of safety analyses. A Microsoft Excel spreadsheet (RADIDOSE) was issued for the evaluation of radiological consequences for accident scenarios often postulated for Hanford. A standard Site Documented Safety Analysis (DSA) detailing the safety management programs was issued for use as a means of compliance with a majority of 3009 Standard chapters. An in-process review was developed between DOE and the Contractor to facilitate DOE approval and provide early course correction. As a result of setting expectations and providing safety analysis tools, the four Hanford Site waste management nuclear facilities were able to integrate into one Master Waste Management Documented Safety Analysis (WM-DSA)

  13. Amateur mythographies: Fan fiction and the myth of myth

    Directory of Open Access Journals (Sweden)

    Ika Willis

    2016-03-01

    Full Text Available This paper draws on classical scholarship on myth in order to critically examine three ways in which scholars and fans have articulated a relationship between fan fiction and myth. These are (1 the notion of fan fiction as a form of folk culture, reclaiming popular story from corporate ownership; (2 the notion of myth as counterhegemonic, often feminist, discourse; (3 the notion of myth as a commons of story and a universal story world. I argue that the first notion depends on an implicit primitivizing of fan fiction and myth, which draws ultimately on the work of Gottfried von Herder in the 18th century and limits our ability to produce historically and politically nuanced understandings of fan fiction. The second notion, which is visible in the work of Henry Jenkins and Constance Penley, is more helpful because of its attention to the politics of narration. However, it is the third model of myth, as a universal story world, where we find the richest crossover between fan fiction's creative power and contemporary classical scholarship on myth, especially in relation to Sarah Iles Johnston's analysis of hyperserial narrative. I demonstrate this through some close readings of fan fiction from the Greek and Roman Mythology fandom on Archive of Our Own. I conclude the paper by extending Johnston's arguments to show that fan-fictional hyperseriality, specifically, can be seen as mythic because it intervenes not only in the narrative worlds of its source materials but also in the social world of its telling.

  14. YACHTING CLUB

    CERN Multimedia

    Yachting Club

    2010-01-01

    TRAVERSEE DU LAC MEETS BOL D’OR It is not entire coincidence that your ever-attentive YCC Committee schedules our Traversée du Lac (dinghies, catamarans, windsurfs - although admittedly not many of the latter these last few seasons) for the same weekend as the rather larger-scale Bol d’Or: it enables our intrepid crews to practise their priority rules as Dona Bertarelli sweeps past with LadyCat and gives you something to watch should the wind drop momentarily ... The rest is history, as we say and your scribe will not repeat here the results, either of the Traversée or of the Bol - go find them on our respective Webs! But many thanks to John and Sarah Fullerton for organising this event and to Wolfgang Adam for ably skippering our new Q-boat. And a gentle reminder to us all, please, that we are fairly short of volunteers on all fronts: not merely routine maintenance, remembering to clean the boat you enjoy from time to time but also - urgently - Q-boat skippers (she&...

  15. Aggression in autism spectrum disorder: presentation and treatment options

    Directory of Open Access Journals (Sweden)

    Fitzpatrick SE

    2016-06-01

    Full Text Available Sarah E Fitzpatrick, Laura Srivorakiat, Logan K Wink, Ernest V Pedapati, Craig A Erickson Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Autism spectrum disorder (ASD is a neurodevelopmental disorder characterized by persistent difficulties in social communication and social interaction, coupled with restricted, repetitive patterns of behavior or interest. Research indicates that aggression rates may be higher in individuals with ASD compared to those with other developmental disabilities. Aggression is associated with negative outcomes for children with ASD and their caregivers, including decreased quality of life, increased stress levels, and reduced availability of educational and social support. Therapeutic strategies including functional behavioral assessment, reinforcement strategies, and functional communication training may have a significant impact in reducing the frequency and intensity of aggressive behavior in individuals with ASD. Pharmacologic treatments, particularly the use of second-generation antipsychotics, may also be of some benefit in reducing aggression in individuals with ASD. With the ever-increasing rate of ASD diagnosis, development of effective therapeutic and pharmacologic methods for preventing and treating aggression are essential to improving outcomes in this disorder. Keywords: autism, autism spectrum disorder, aggression, treatment, antipsychotics, applied behavior analysis

  16. Pharmacologic management of bone-related complications and bone metastases in postmenopausal women with hormone receptor-positive breast cancer

    Directory of Open Access Journals (Sweden)

    Yardley DA

    2016-05-01

    Full Text Available Denise A Yardley1,2 1Sarah Cannon Research Institute, Nashville, TN, USA; 2Tennessee Oncology, Nashville, TN, USA Abstract: There is a high risk for bone loss and skeletal-related events, including bone metastases, in postmenopausal women with hormone receptor-positive breast cancer. Both the disease itself and its therapeutic treatments can negatively impact bone, resulting in decreases in bone mineral density and increases in bone loss. These negative effects on the bone can significantly impact morbidity and mortality. Effective management and minimization of bone-related complications in postmenopausal women with hormone receptor-positive breast cancer remain essential. This review discusses the current understanding of molecular and biological mechanisms involved in bone turnover and metastases, increased risk for bone-related complications from breast cancer and breast cancer therapy, and current and emerging treatment strategies for managing bone metastases and bone turnover in postmenopausal women with hormone receptor-positive breast cancer. Keywords: breast cancer, bone metastases, hormone receptor-positive, bone-related complications, interventions, management and management strategies, estrogen receptor-positive

  17. Report on the second international workshop on residential radon: Workshop proceedings

    International Nuclear Information System (INIS)

    1991-07-01

    As a follow-on to the first International Workshop on Residential Radon Epidemiology held in Alexandria VA, on July 24-26, 1989, a Second Workshop was convened, in Alexandria, VA, July 22-23 1991, also under the auspices of the US Department of Energy and the Commission of European Communities. The Workshop, co-chaired by Jonathan Samet and Jan Stolwijk, was attended by 20 active participants from seven countries representing epidemiologic studies recently completed, currently in progress, or in the last stages of preparation. The studies reported on are being conducted in the United States, Canada, Sweden, the United Kingdom, France, Belgium, Germany and the Peoples' Republic of China. The invited presentations that initiated the Workshop focused on a number of methodological problems that have surfaced in the last few years. Among these were: (1) the difficulties in predicting indoor radon concentrations, based on geologic information, (discussed by Alan Tanner, formerly of the US Geologic Survey); (2) the relationships between indoor radon concentrations and building characteristics (discussed by Richard Sextro, Lawrence Berkeley Laboratory, USA); (3) the approaches to analysis of case-control studies in radon epidemiology (discussed by Sarah Darby, Imperial Cancer Research Fund, UK); (4) statistical approaches to error in measurements and missing data (discussed by Donna Spiegelman, Tufts University, USA); (5) preliminary results of a data pooling effort dealing with several different studies of residential radon epidemiology and the lessons to be drawn from this effort (discussed by Jay Lubin, US National Cancer Institute)

  18. Gold Medal for Finnish Health in All Policies Book

    Directory of Open Access Journals (Sweden)

    Ray Lewis

    2014-02-01

    Full Text Available This article is a review of the book “Health in All Policies: Seizing opportunities, implementing policies” edited by Kimmo Leppo, Eeva Ollila, Sebastián Peña, Matthias Wismar, and Sarah Cook. This book (printed and online publication was published by the Finnish Ministry of Social Affairs and Health, Finland in 2013 (1. The book is freely available at http://www.euro.who.int/__data/assets/pdf_file/0007/188809/Health-in-All-Policies-final.pdf. The main features, structure, and highlighted contents of the book are briefly sketched out in this review. The book promotes understanding of a Health in All Policies (HiAP approach, the history, and the scientific evidence of effectiveness available to apply the HiAP concept in order to overcome challenges faced by policy-makers. HiAP is a relatively novel approach which arises from the traditional idea that health is not only medicine (2. The book offers lessons to policy-makers and managers on how to apply the HiAP approach. It further highlights the health sector’s role in developing healthy public policies. In addition, the book provides examples of structures to foster collaboration, coherence, and participation among stakeholders from different government portfolios and responsibilities. The book further provides invaluable insights for politicians, researchers, and civil society advocates.

  19. Being more conscientious, collaborative, and confident in addressing patients' fears and anxieties: nurses' perspectives

    Directory of Open Access Journals (Sweden)

    Beswick SE

    2013-08-01

    Full Text Available Susan E Beswick,1 Sandee Westell,1 Sarah Sweetman,1 Charmaine Mothersill,1 Lianne P Jeffs1,21St Michael's Hospital, Toronto, ON, Canada; 2Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada Background: Developing a therapeutic partnership between patient and nurse is key to ensuring the patient's needs and preferences are identified, addressed, and valued as a key patient safety goal. There is growing recognition that patients living with chronic lung diseases often experience increased levels of stress, anxiety, and depression compared to their healthy counterparts. Creating strategies for early identification and management of patients' fears and anxieties is a strategy to minimize anxiety and depressive symptoms.Methods: This article provides an overview of a qualitative study which explored nurses' perceptions and experiences associated with the implementation of the Registered Nurses' Association of Ontario's Establishing Therapeutic Relationships Best Practice Guideline that focused on strategies to alleviate patients' fears and anxieties on one respirology unit.Results: Study findings suggest that involvement in Best Practice Guideline implementation enabled nurses to address patients' fears and anxieties in a focused, conscientious manner and to be more collaborative and confident in their care.Conclusion: Providing opportunities for nurses to learn and apply evidence-based practice around therapeutic patient-centered care is a key step in ensuring a quality patient experience.Keywords: evidence-based practice, best practice guideline, therapeutic relationship, fear and anxiety, collaborative practice

  20. Kepler Planets Tend to Have Siblings of the Same Size

    Science.gov (United States)

    Kohler, Susanna

    2017-11-01

    After 8.5 years of observations with the Kepler space observatory, weve discovered a large number of close-in, tightly-spaced, multiple-planet systems orbiting distant stars. In the process, weve learned a lot about the properties about these systems and discovered some unexpected behavior. A new study explores one of the properties that has surprised us: planets of the same size tend to live together.Orbital architectures for 25 of the authors multiplanet systems. The dots are sized according to the planets relative radii and colored according to mass. Planets of similar sizes and masses tend to live together in the same system. [Millholland et al. 2017]Ordering of SystemsFrom Keplers observations of extrasolar multiplanet systems, we have seen that the sizes of planets in a given system arent completely random. Systems that contain a large planet, for example, are more likely to contain additional large planets rather than additional planets of random size. So though there is a large spread in the radii weve observed for transiting exoplanets, the spread within any given multiplanet system tends to be much smaller.This odd behavior has led us to ask whether this clustering occurs not just for radius, but also for mass. Since the multiplanet systems discovered by Kepler most often contain super-Earths and mini-Neptunes, which have an extremely large spread in densities, the fact that two such planets have similar radii does not guarantee that they have similar masses.If planets dont cluster in mass within a system, this would raise the question of why planets coordinate only their radii within a given system. If they do cluster in mass, it implies that planets within the same system tend to have similar densities, potentially allowing us to predict the sizes and masses of planets we might find in a given system.Insight into MassesLed by NSF graduate research fellow Sarah Millholland, a team of scientists at Yale University used recently determined masses for

  1. "Y el resto se hace con gritos": Notas sobre literatura y teatro

    Directory of Open Access Journals (Sweden)

    Marcela Arpes

    2009-07-01

    Full Text Available Quisiera comenzar con un, más o menos extenso, listado de obras de teatro que aún permanecen en cartel o, en todo caso, algunas de ellas lo estuvieron hasta marzo, en salas oficiales y alternativas del circuito teatral porteño pero, también, del interior del país: Tres para el té sobre textos de Lewis Carroll; Galileo, sobre la mesa sobre el texto de Bertolt Brecht; Federico tuvo un sueño, inspirada en el cuento de Antonio Tabucchi y en textos poéticos de Federico García Lorca; Los siete locos, de Roberto Arlt; Crave de Sarah Kane; Cielo rojo, el sueño Bolchevique del poeta Vladimir Maiacovsky; La Manchada, sobre Cuentos de la selva de Horacio Quiroga; Doña Flor y sus dos maridos de Jorge Amado; Grande y Pequeño del escritor alemán contemporáneo Botho Strauss; El diario de Anna Frank; Esa que no eres sobre textos de Alejandra Pizarnik, obra que recibió este verano el premio Estrella de Mar en la categoría mejor espectáculo del teatro off; La revolución silenciada sobre la obra Tres jueces para un largo silencio de Andrés Lizarraga, aquel escritor y dramaturgo argentino, el primero en recibir el premio Casas de las Américas; El mundo ha vivido equivocado de Roberto Fontanarrosa; Una vida más cuerda mañana, sobre textos de Griselda Gambaro, Sarah Kane y Vicente Zito Lema; La Divina Comedia de Dante Alighieri: Mi madre Mi Tierra donde conviven textos literarios de autores como Gloria Fuertes y Federico García Lorca; Sabor a Freud de José Pablo Feinman; El Corazón Delator de Edgar Allan Poe; El Relato de Lady Sotheby. de Marlene Spindler, espectáculo basado en textos de Fiodor Dostoyevsky y Stefan Zweig; Juicio al tango, sobre textos de Leopoldo Marechal; El día que Nietzsche lloró, título de la primera novela del profesor de psiquiatría de la Universidad de Stanford, Irvin Yalom; El último encuentro de Sándor Márai, versión escénica de la exitosa novela “El último encuentro” de Sándor Márai aquel escritor

  2. MotivATE: A Pretreatment Web-Based Program to Improve Attendance at UK Outpatient Services Among Adults With Eating Disorders.

    Science.gov (United States)

    Muir, Sarah; Newell, Ciarán; Griffiths, Jess; Walker, Kathy; Hooper, Holly; Thomas, Sarah; Thomas, Peter W; Arcelus, Jon; Day, James; Appleton, Katherine M

    2017-07-26

    on the MotivATE program. Participants related well to the stories used. Nonetheless, because of feedback, we further modified the program in line with patients' stage of change and addressed issues with the language used. A consultation with service staff meant that we could make clear implementation plans. Finally, a randomized controlled trial is currently underway to evaluate the MotivATE program. Using intervention mapping, we have developed a novel pretreatment Web-based program that is acceptable to people with eating disorders. To our knowledge, this is the first such program. The model of development described here could be a useful template for designing further programs for other difficult-to-engage populations. ©Sarah Muir, Ciarán Newell, Jess Griffiths, Kathy Walker, Holly Hooper, Sarah Thomas, Peter W Thomas, Jon Arcelus, James Day, Katherine M Appleton. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 26.07.2017.

  3. "Y el resto se hace con gritos": Notas sobre literatura y teatro

    Directory of Open Access Journals (Sweden)

    Marcela Arpes

    2009-06-01

    Full Text Available Quisiera comenzar con un, más o menos extenso, listado de obras de teatro que aún permanecen en cartel o, en todo caso, algunas de ellas lo estuvieron hasta marzo, en salas oficiales y alternativas del circuito teatral porteño pero, también, del interior del país: Tres para el té sobre textos de Lewis Carroll; Galileo, sobre la mesa sobre el texto de Bertolt Brecht; Federico tuvo un sueño, inspirada en el cuento de Antonio Tabucchi y en textos poéticos de Federico García Lorca; Los siete locos, de Roberto Arlt; Crave de Sarah Kane; Cielo rojo, el sueño Bolchevique del poeta Vladimir Maiacovsky; La Manchada, sobre Cuentos de la selva de Horacio Quiroga; Doña Flor y sus dos maridos de Jorge Amado; Grande y Pequeño del escritor alemán contemporáneo Botho Strauss; El diario de Anna Frank; Esa que no eres sobre textos de Alejandra Pizarnik, obra que recibió este verano el premio Estrella de Mar en la categoría mejor espectáculo del teatro off; La revolución silenciada sobre la obra Tres jueces para un largo silencio de Andrés Lizarraga, aquel escritor y dramaturgo argentino, el primero en recibir el premio Casas de las Américas; El mundo ha vivido equivocado de Roberto Fontanarrosa; Una vida más cuerda mañana, sobre textos de Griselda Gambaro, Sarah Kane y Vicente Zito Lema; La Divina Comedia de Dante Alighieri: Mi madre Mi Tierra donde conviven textos literarios de autores como Gloria Fuertes y Federico García Lorca; Sabor a Freud de José Pablo Feinman; El Corazón Delator de Edgar Allan Poe; El Relato de Lady Sotheby. de Marlene Spindler, espectáculo basado en textos de Fiodor Dostoyevsky y Stefan Zweig; Juicio al tango, sobre textos de Leopoldo Marechal; El día que Nietzsche lloró, título de la primera novela del profesor de psiquiatría de la Universidad de Stanford, Irvin Yalom; El último encuentro de Sándor Márai, versión escénica de la exitosa novela “El último encuentro” de Sándor Márai aquel escritor

  4. Introduction and Committees

    Science.gov (United States)

    Angelova, Maia; Zakrzewski, Wojciech; Hussin, Véronique; Piette, Bernard

    2011-03-01

    Valladolid University, Spain George PogosyanUNAM, Mexico, JINR, Dubna, Russia Christoph SchweigertUniversity of Hamburg, Germany Reidun TwarockYork University, UK Luc VinetMontréal University, Canada Apostolos VourdasBradford University, UK Kurt WolfUNAM, Mexico Local Organising Committee Maia Angelova - ChairNorthumbria University, Newcastle Wojtek Zakrzewski - ChairDurham University, Durham Sarah Howells - SecretaryNorthumbria University, Newcastle Jeremy Ellman - WebNorthumbria University, Newcastle Véronique HussinNorthumbria, Durham and University of Montréal Safwat MansiNorthumbria University, Newcastle James McLaughlinNorthumbria University, Newcastle Bernard PietteDurham University, Durham Ghanim PutrusNorthumbria University, Newcastle Sarah ReesNewcastle University, Newcastle Petia SiceNorthumbria University, Newcastle Anne TaorminaDurham University, Durham Rosemary ZakrzewskiAccompanying persons programme Lighthouse Photograph by Bernard Piette: Souter Lighthouse, Marsden, Tyne and Wear, England

  5. Qualidade de vida em pessoas com lesão medular traumática: um estudo com o WHOQOL-bref Quality of live in people with traumatic spinal cord injury: a study with WHOQOL-bref

    Directory of Open Access Journals (Sweden)

    Luciana Neves da Silva Bampi

    2008-03-01

    Full Text Available OBJETIVOS: Conhecer a percepção de qualidade de vida em pessoas com lesão medular traumática, utilizando a metodologia adotada pela Organização Mundial de Saúde (OMS. MÉTODOS: Trata-se de uma pesquisa transversal, na qual foi realizado um estudo descritivo para conhecer as características sociodemográficas e a distribuição das lesões medulares traumáticas na amostra estudada. Em seguida, com o intuito de conhecer a percepção da qualidade de vida dessa população, utilizou-se o WHOQOL - bref. As análises estatísticas realizadas incluíram análises descritivas de freqüência, tendência central e dispersão e análise inferencial de comparação entre os domínios. O estudo transcorreu de janeiro de 2005 a maio de 2006 e foi desenvolvido com pessoas no momento de sua admissão no programa de reabilitação do Hospital Sarah Brasília. Utilizou-se uma amostra de conveniência, com 111 entrevistados. RESULTADOS: Os indivíduos estudados são, em sua maioria, homens jovens, solteiros, possuidores do ensino fundamental e vítimas de acidentes de trânsito e de armas de fogo. A percepção da qualidade de vida demonstrou que os domínios que refletiram os piores escores de avaliação estavam relacionados ao meio ambiente e à saúde física; e os mais bem avaliados estavam ligados à saúde psicológica e às relações sociais. CONCLUSÃO: O estudo permitiu conhecer a percepção de qualidade de vida do grupo pesquisado. Recomenda-se estudo que inclua tetra-plégicos e lesados medulares não traumáticos, com o intuito de se obter uma avaliação mais global.OBJECTIVES: To find the perception of quality of life in people with traumatic spinal cord injury using the methodology adopted by the World Health Organization (WHO. METHODS: This was a cross-sectional study in which a descriptive study was first carried out to better understand the socio-demographic characteristics and the distribution of traumatic spinal cord injury in the

  6. Secondary stressors and extreme events and disasters: a systematic review of primary research from 2010-2011

    Science.gov (United States)

    Lock, Sarah; Rubin, G. James; Murray, Virginia; Rogers, M. Brooke; Amlôt, Richard; Williams, Richard

    2012-01-01

    reporting; family and social stressors; stress arising from loss of leisure and recreation; and stress related to changes in people’s views of the world or themselves. Limitations in this review include its focus on studies published in 2010 and 2011, which may have led to some secondary stressors being excluded. Assumptions have been made about whether certain items are secondary stressors, if unclear definitions made it difficult to differentiate them from primary stressors. Conclusions This is the first review, to our knowledge, that has developed a typology of secondary stressors that occur following extreme events. We discuss the differing natures of these stressors and the criteria that should be used to differentiate primary and secondary stressors. Some secondary stressors, for example, are entities in themselves, while others are persisting primary stressors that exert their effects through failure of societal responses to disasters to mitigate their immediate impacts. Future research should aim to define secondary stressors and investigate the interactions between stressors. This is essential if we are to identify which secondary stressors are amenable to interventions which might reduce their impacts on the psychosocial resilience and mental health of people who are affected by disasters. Corresponding Author: Dr Sarah Lock, Extreme Events and Health Protection, London, 151 Buckingham Palace Road, London, SW1W 9SZ. E-mail: sarah.lock@hpa.org.uk PMID:23145350

  7. Criar uma idiocultura para promover o desenvolvimento de crianças com paralisia cerebral Creating an idioculture to promote the development of children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Lucia Willadino Braga

    2010-04-01

    Full Text Available Este estudo apresenta os resultados preliminares da adaptação de um sistema educacional, chamado Quinta Dimensão, no qual a interação social é um meio para a generalização da informação e base para o desenvolvimento de habilidades. Foi criado originalmente por Michael Cole no Laboratório de Cognição Humana Comparada, Universidade da Califórnia, San Diego, e pela primeira vez é aplicado em um contexto de reabilitação com crianças com lesão cerebral na Rede SARAH de Neurorreabilitação, Brasília. Alunos de graduação em psicologia e pedagogia participam do programa e interagem de maneira lúdica e educativa com crianças com paralisia cerebral. Ambos são envolvidos em atividades de aprendizagem colaborativa. Na interação com a criança, os alunos são encorajados a colocar em prática conceitos teóricos formais e, também, vivências individuais. Resultados indicam efeitos positivos sobre o desenvolvimento da criança e aprendizagem do aluno de graduação e mostram caminhos alternativos na educação da criança deficiente. Neste artigo, descrevemos as alterações feitas no programa original para adaptá-lo à reabilitação configurada, assim como os artefatos que medeiam a atividade, necessário para a interação e expressão da criança com paralisia cerebral. Também são discutidos e apresentados os efeitos da atividade sobre o desenvolvimento da criança - com base em relatórios dos pais - e do impacto sobre o processo de aprendizagem dos alunos de graduação. O programa abre caminhos alternativos para uma reflexão sobre e educação da criança com lesão cerebral, com base no desenvolvimento do potencial individual, o contexto e os interesses.This study presents the preliminary results of the adaptation of an educational system called the Fifth Dimension (5D, in which social interaction is a means for generalizing information and a basis for the development of skills beyond the constituent tasks. Originally

  8. Descrição da aptidão inicial para natação em lesionados medulares Description of initial swimming ability in patients with spinal cord injury

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    Ana Cláudia Raposo Melo

    2009-12-01

    Full Text Available Este estudo tem por objetivos verificar o retorno à natação após a lesão medular e descrever a aptidão inicial de lesionados medulares para o nado como parte das atividades do programa de reabilitação no Hospitalar Sarah-Centro. MÉTODOS: Foram avaliados 170 pacientes com diagnóstico de paraplegia e tetraplegia, em três etapas - levantamento de dados em prontuário, entrevista oral e avaliação do padrão do nado. Os resultados apontaram que grande parte dos pacientes não entrou na piscina ou realizou nado após a lesão medular. A avaliação da adaptação ao meio líquido após a lesão medular demonstrou que grande parte dos pacientes realizou a imersão e flutuação de forma independente, porém, apresentando dificuldade em mudar de decúbito dentro da água. Apenas uma pequena porcentagem retomou a natação após a lesão medular; foi também verificada redução no total dos sujeitos que nadavam regularmente antes. A avaliação apontou que os nados crawl e de costas foram realizados por metade dos avaliados; apenas uma pequena parte realizou nado de peito. CONCLUSÃO: Após a avaliação dos relatos dos pacientes, verificou-se redução na prática da natação, seja como atividade esportiva, física ou de lazer após a lesão medular, apesar de a aptidão para o nado não ter sofrido grandes alterações.Pysical activity, particularly swimming, that brings a lot of benefits to subjects with spinal cord injury, can be started during rehabilitation. The aims of this study were to describe the initial ability to swim of patients with spinal cord injury during the rehabilitation program at the Sarah Hospital - Center. METHODS: 170 patients were evaluated in three steps - medical records data collection, oral interview and swimming evaluation. The results showed that a large proportion of patients did not enter the swimming pool or swam after spinal cord injury. Only a small part returned to swimming after the spinal cord

  9. Corrigendum.

    Science.gov (United States)

    2018-01-01

    Corrigendum to: Carter G, Page A, Large M, et al. (2016) Royal Australian and New Zealand College of Psychiatrists clinical practice guideline for the management of deliberate self-harm. Australian and New Zealand Journal of Psychiatry 50: 939-1000. Readers should note an error in the published version of this article: The previous list of authors and affiliations inadvertently omitted the details of Dr Michael Dudley. The correct author list and affiliation details appear below: Gregory Carter 1,2,3 , Andrew Page 1,4 , Matthew Large 1,5 , Sarah Hetrick 1,6 , Allison Joy Milner 1,7,8 , Nick Bendit 1,9,10 , Carla Walton 1,11 , Brian Draper 1,12,13 , Philip Hazell 1,14 , Sarah Fortune 1,15,16,17 , Jane Burns 1,18,19,20 , George Patton 1,21,22,23,24 , Mark Lawrence 1,25 , Lawrence Dadd 1,26,27,28,29 , Michael Dudley 1, 12 , Jo Robinson 1,6 , and Helen Christensen 1,30 1 Clinical Practice Guideline for Deliberate Self-harm Working Group, RANZCP, Melbourne, Victoria, Australia 2 Centre for Translational Neuroscience and Mental Health, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia 3 Department of Consultation Liaison Psychiatry, Calvary Mater Newcastle Hospital, Waratah, NSW, Australia 4 Centre for Health Research, Western Sydney University, Richmond, NSW, Australia 5 School of Psychiatry, The University of New South Wales, Sydney, NSW, Australia 6 Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia 7 Centre for Population Health Research, School of Health and Social Development, Deakin University, Burwood VIC, Australia 8 Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia 9 School of Medicine and Public Health, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia 10 School of Psychology, Faculty of Science and Information Technology, The University of Newcastle, Callaghan, NSW

  10. New developments in the treatment of hypoactive sexual desire disorder – a focus on Flibanserin

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    Jayne CJ

    2017-04-01

    Full Text Available Christopher J Jayne,1 Michael J Heard,2 Sarah Zubair,3 Dustie L Johnson4 1Greater Houston Urogyn, 2Department of Ob/Gyn, St Joseph Medical Center, The Heard Institute, 3Department of Natural Sciences, The University of Houston – Downtown, Houston, 4Reproductive Solutions Inc., Midland, TX, USA Abstract: The objective of the authors is to highlight the historical complexities for the diagnosis and treatment of hypoactive sexual desire disorder (HSDD with a focus on Flibanserin. A systematic review of the medical literature published in PubMed using the search terms HSDD and Flibanserin was conducted. Each author reviewed the results of the systematic review for articles to include in this study. HSDD is defined as a persistent or recurrent deficiency or absence of sexual fantasies and desire for sexual activity causing marked distress or interpersonal difficulty that is not better accounted for by another diagnosis. Until 2015, only homeopathic products and off-label use of prescription medications were medical treatment options for women with HSDD. Flibanserin, approved by the US Food and Drug Administration (FDA in 2015, is the first to target female HSDD in premenopausal women. Flibanserin is a centrally acting nonhormonal oral medication taken once daily that affects serotonin, dopamine and norepinephrine levels, the key neurotransmitters in the biology of desire. Understanding prescribing guidelines and awareness of black box warnings is paramount for prescribers. Adherence to proper oversight will ensure Flibanserin can fulfil an unmet need for an FDA approved prescription medication for the treatment of HSDD in premenopausal women. Keywords: flibanserin, hypoactive sexual desire, women’s sexual health

  11. Cognitive-behavioral therapy for patients with irritable bowel syndrome: current insights

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    Kinsinger SW

    2017-07-01

    Full Text Available Sarah W Kinsinger Behavioral Medicine for Digestive Health, Division of Gastroenterology and Nutrition, Loyola University Medical Center, Maywood, IL, USA Abstract: Irritable bowel syndrome (IBS is a chronic gastrointestinal (GI condition associated with significant health care utilization and quality-of-life impairment. Latest research indicates that the brain–gut axis plays a key role in the disorder, and the presence of psychological factors and central processing deficits contribute to symptom severity and disability. Psychological therapies as a whole have demonstrated good efficacy in reducing the severity of IBS symptoms. Cognitive-behavioral therapy (CBT has been tested most rigorously in multiple randomized controlled trials and consistently demonstrates significant and durable effects on IBS symptoms and quality of life. Various protocols for treating IBS have been developed, and most recent advances in the field include exposure-based treatments to target symptom-specific anxiety as well as modified delivery methods, including internet-based treatment models. Despite the well-documented advantages of CBT for IBS, it has been poorly disseminated and few patients have access to this treatment. The primary barrier to dissemination is the limited number of therapists with adequate training in GI psychology to provide this evidence-based intervention. Future developments in the field need to focus on training opportunities to equip more therapists to competently provide CBT for this population. Further efforts to develop telemedicine platforms for delivering this intervention will also improve accessibility for patients. Keywords: irritable bowel syndrome, functional gastrointestinal disorders, cognitive-behavioral therapy

  12. Junk Food Marketing on Instagram: Content Analysis.

    Science.gov (United States)

    Vassallo, Amy Jo; Kelly, Bridget; Zhang, Lelin; Wang, Zhiyong; Young, Sarah; Freeman, Becky

    2018-06-05

    Omnipresent marketing of processed foods is a key driver of dietary choices and brand loyalty. Market data indicate a shift in food marketing expenditures to digital media, including social media. These platforms have greater potential to influence young people, given their unique peer-to-peer transmission and youths' susceptibility to social pressures. The aim of this study was to investigate the frequency of images and videos posted by the most popular, energy-dense, nutrient-poor food and beverage brands on Instagram and the marketing strategies used in these images, including any healthy choice claims. A content analysis of 15 accounts was conducted, using 12 months of Instagram posts from March 15, 2015, to March 15, 2016. A pre-established hierarchical coding guide was used to identify the primary marketing strategy of each post. Each brand used 6 to 11 different marketing strategies in their Instagram accounts; however, they often adhered to an overall theme such as athleticism or relatable consumers. There was a high level of branding, although not necessarily product information on all accounts, and there were very few health claims. Brands are using social media platforms such as Instagram to market their products to a growing number of consumers, using a high frequency of targeted and curated posts that manipulate consumer emotions rather than present information about their products. Policy action is needed that better reflects the current media environment. Public health bodies also need to engage with emerging media platforms and develop compelling social counter-marketing campaigns. ©Amy Jo Vassallo, Bridget Kelly, Lelin Zhang, Zhiyong Wang, Sarah Young, Becky Freeman. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 05.06.2018.

  13. THE THEATRICAL POSTER BETWEEN ADVERTISING AND ARTISTIC CREATION

    Directory of Open Access Journals (Sweden)

    TIPA VIOLETA

    2016-12-01

    Full Text Available If the great Constantin Stanislavski said that the theatre starts from the cloak-room, today, in the era of broadcasting, we could reformulate the idea, confi rming that the theatre starts with the poster. Posters in the modern variant appeared with the emergence of the printing press. J. Gutenberg’s invention in 1453 became the beginning of the third information revolution, signifying a new stage in the evolution of commercials. Th e poster tradition has taken a new momentum in the nineteenth century. Let us remember such masters as the famous French painter Henri de Toulouse-Lautrec and the Czech Alphonse Mucha (who became popular thanks to the posters with Sarah Bernhardt, and who laid the foundation of the principles of the European theatre poster. The analysis of theatre posters from the Republic of Moldova, certifi es their evolution from text information to the artistic-aesthetic image, from the purely informative image to the suggestive-symbolic one. To exemplify these ideas, we will use posters created for the shows of the „Licurici” and „Guguţă” Puppet Th eatres. Th e authors’ purpose was to present in the foreground of the show the title and the main characters keeping the same style that arouses the attention and curiosity of children. The posters, that promote the meanings and symbols of the message, are increasingly required. So, in a symbolic key, are made the posters for the plays „Swan Flight” (by Andersen, „Făt-Frumos din lacrimă” (by Mihai Eminescu, directed by Nina Zabrodin; „Planeta de rouă” (by Grigore Vieru, directed by Ion Puiu, „Cămașa norocului”, directed by Tatiana Cojocaru etc. Currently the poster (theatre poster has become an art form and submits peculiar artistic regularities and peculiarities, requiring not only a high artistic level of achievement, but also a conceptual one.

  14. White Papers Emerging from Women in Astronomy IV

    Science.gov (United States)

    Morrison, Nancy D.; Women in Astronomy IV Organizing Committee and conference attendees

    2018-06-01

    During the Women in Astronomy IV meeting in Austin, TX, in June, 2017, planning workshops were held for several white papers. This talk will present those papers' main points and/or introduce the papers' lead authors to make those presentations. Each paper's lead authors, its title, and a brief summary follow.Nancy Morrison and Van Dixon, "Graduate Admissions in a Post-GRE World": Research has shown that the use of a hard cutoff in GRE scores results in lack of ethnic and gender diversity in admitted cohorts. In addition, GRE scores are not well correlated with various measures of success in graduate school and beyond. Alternative admission metrics, including non-cognitive assessments, are explored. This talk will complement the related presentation to be given by A. Rudolph.Lia Corrales, "Inclusion and Access in Teaching and Training": equitable administration of university teaching, including hiring and evaluation of instruction; best practices for ensuring that all students are included in classroom learning; improvements in training of teachers and group leaders; and inclusivity in research groups and institutions.Sarah Tuttle and Aparna Venkatesan, "'Benefits & Rights' Policy": best practices for institutions to support people with disabilities in terms of universal design and to support families in terms of family and dependent care leave policies and health insurance. Venkatesan will speak about "Building an Inclusive Workplace."Dara Norman, "Demographics": Demographic surveys need to include intersectionality among not only personal demographics, (such as race, gender, sexual orientation, etc.) but also workforce demographics (such as area of research and career status). This information is essential for an understanding of specific processes affecting underrepresented groups in astronomy. Norman will address this and related topics separately.

  15. Outcome for esophageal cancer following treatment with chemotherapy and radiotherapy but not esophagectomy: nonsurgical treatment of esophageal cancer

    Directory of Open Access Journals (Sweden)

    Urs Zingg

    2009-07-01

    Full Text Available Urs Zingg1,2, Dennis DiValentino1, Alexander McQuinn1, Ahmad Mardzuki1, Sarah K Thompson2,  Christos S Karapetis1,3, David I Watson11Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia; 2Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia; 3Department of Medical Oncology, Flinders Medical Centre, Bedford Park, South Australia, AustraliaBackground: More than 50% of patients with esophageal cancer are not suitable for surgery. The aim of this study was to analyze the outcome of patients undergoing standard nonsurgical treatment.Methods: Data of all patients undergoing nonsurgical treatment for esophageal cancer were identified from a prospective database.Results: Seventy-five patients were treated for localized disease, and 52 for metastatic disease at diagnosis. Except for age, which was higher in patients without metastases, there were no significant differences between the patients with vs. without metastatic disease. Kaplan–Meier analysis showed a median survival of 10.8 months for all patients. There was a significant difference in survival (p < 0.001 between the groups with versus without metastases, with median survival in the patients without metastases 13.6 months versus 6.5 months in patients with metastases. Patients undergoing nonsurgical treatment for localized disease had a five-year survival of 12%. No significant difference between adenocarcinoma and squamous cell carcinoma was identified. Subanalysis of patients who received chemoradiotherapy revealed similar results to the overall group of patients.Conclusion: In patients with localized disease at diagnosis, long-term survival can be achieved in some patients, whereas five-year survival is rare in patients who present with metastatic disease.Keywords: nonsurgical treatment, esophageal cancer, chemoradiotherapy, metastases, survival

  16. From Territorial to Temporal Ambitions: The Politics of Time and Imagination in Massive Multiplayer Online Forecasting Games

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    Lonny J. Avi Brooks

    2015-09-01

    Full Text Available In 2010, the online forecasting game Urgent Evoke, produced by Jane McGonigal, former Director of Gaming at the Institute for the Future and the World Bank Institute, elicited praise by gaming critics as a model for “serious gaming.” The game promised to show how players could think about long-term solutions to urgent social problems like hunger, poverty, conflict, and climate change using the African continent as its test bed. Players imagined future temporal outcomes through remixing media. In a qualitative analysis of actual game play during the real-time introduction of the game for teaching organizational communication, Evoke became a platform for student inquiry for questioning its underlying design as an expansion of territorial and temporal conquest. Evoke served as a springboard for building a literacy of critical time among students in accessing stakeholder power to determine the future. Students challenged, created, and followed the cultural capital of promissory visions in circulation. The curriculum design for using serious and forecasting games like Evoke must account for the conceptual development of what Sarah Sharma calls critical time or chronopolitics, a hidden politics of time that shapes our approaches to cultures, organizations, and innovation. By placing spatial and temporal dynamics center stage, we investigated how serious games produce a chronopolitics of time differentiating among people by class and ethnicity. Alternative Reality Games offer the potential for building a literacy of critical forecasting time to understand the practices for anticipating the future as temporal networks of power, different and uneven.

  17. Gridded sunshine duration climate data record for Germany based on combined satellite and in situ observations

    Science.gov (United States)

    Walawender, Jakub; Kothe, Steffen; Trentmann, Jörg; Pfeifroth, Uwe; Cremer, Roswitha

    2017-04-01

    The purpose of this study is to create a 1 km2 gridded daily sunshine duration data record for Germany covering the period from 1983 to 2015 (33 years) based on satellite estimates of direct normalised surface solar radiation and in situ sunshine duration observations using a geostatistical approach. The CM SAF SARAH direct normalized irradiance (DNI) satellite climate data record and in situ observations of sunshine duration from 121 weather stations operated by DWD are used as input datasets. The selected period of 33 years is associated with the availability of satellite data. The number of ground stations is limited to 121 as there are only time series with less than 10% of missing observations over the selected period included to keep the long-term consistency of the output sunshine duration data record. In the first step, DNI data record is used to derive sunshine hours by applying WMO threshold of 120 W/m2 (SDU = DNI ≥ 120 W/m2) and weighting of sunny slots to correct the sunshine length between two instantaneous image data due to cloud movement. In the second step, linear regression between SDU and in situ sunshine duration is calculated to adjust the satellite product to the ground observations and the output regression coefficients are applied to create a regression grid. In the last step regression residuals are interpolated with ordinary kriging and added to the regression grid. A comprehensive accuracy assessment of the gridded sunshine duration data record is performed by calculating prediction errors (cross-validation routine). "R" is used for data processing. A short analysis of the spatial distribution and temporal variability of sunshine duration over Germany based on the created dataset will be presented. The gridded sunshine duration data are useful for applications in various climate-related studies, agriculture and solar energy potential calculations.

  18. Integrating evidence into practice: use of McKenzie-based treatment for mechanical low back pain

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    Clarke S

    2011-11-01

    Full Text Available Angela Dunsford1, Saravana Kumar1,2, Sarah Clarke1 1International Centre for Allied Health Evidence, 2School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia Abstract: Low back pain (LBP is a major health issue with significant socioeconomic implications in most Western countries. Many forms of treatment have been proposed and investigated in the past, with exercise being a commonly prescribed intervention. Within allied health, in particular physiotherapy, there has been a growing movement that recognizes the role of the McKenzie method in treating LBP. Within the McKenzie framework, directional preference (DP exercises are one such intervention, with preliminary data demonstrating its effectiveness in the management of LBP. In this paper, we aim to integrate the evidence from current research, identified using a systematic review, and utilize a practical real-life case scenario to outline how evidence from the literature can be implemented in clinical practice. The findings from the systematic review indicate that DP exercises may have positive effects in the management of LBP. While the body of evidence to support this is limited (only four studies and therefore modest at best, it does provide some emerging evidence to support the use of DP exercises in clinical practice. Despite this, gaps also persist in the literature on DP exercises, and this relates to the exercise parameters and the compliance rates. Recognizing this dichotomy (modest evidence in some areas and evidence gaps in other areas, which is likely to confront health practitioners, using a practical approach with a real-life clinical scenario, we outline how the evidence from the systematic review can be implemented in clinical practice. This approach builds on the philosophy of evidence-based practice of integrating research evidence with clinical expertise and patient values. Keywords: low back pain, McKenzie method, directional

  19. Development of a Healthy Lifestyle Mobile App for Overweight Pregnant Women: Qualitative Study.

    Science.gov (United States)

    Lau, Ying; Cheng, Ling Jie; Chi, Claudia; Tsai, Cammy; Ong, Kai Wen; Ho-Lim, Sarah Su Tin; Wang, Wei; Tan, Kian-Lee

    2018-04-23

    Mobile apps are becoming an increasingly ubiquitous platform for delivery of health behavior interventions among overweight and obese perinatal women. However, only a few methodological guidelines on integrating theory, evidence, and qualitative research for their designs are available. The aim of this study was to develop a theory-based, evidence-driven, and user-centered healthy lifestyle app targeting overweight and obese multiethnic pregnant women. This paper illustrates how intervention development may be enriched with theoretical basis, systematic review, and qualitative study. An individual face-to-face interview was performed to incorporate the user's involvement in the design. These interviews were audiotaped and transcribed. Thematic analysis technique was used for emerging themes. Integrated concepts of social cognitive theory of self-regulation, self-regulation model, and strength model of self-control were selected as bases of the intervention. Evidence from our systematic review and meta-analysis provided the strongest evidence for the development of intervention. We invited 16 obese or overweight pregnant women to participate in a semistructured interview . The following key themes emerged: content, platform, interactivity, format, and functionality. Apps are a favorable technology platform for healthy diet advice, appropriate physical exercise, and weight management because they are user-friendly and convenient. The app used in this study contains culture-specific, pregnancy-related, and credible contents, including educational, professional and peer support, and self-monitoring domains. The design should include aesthetic appeal, visualized features, and interactive multimedia. A 3-step process integrating theoretical basis, evidence from systematic review, and research findings from target users can be considered a guide for future app development. ©Ying Lau, Ling Jie Cheng, Claudia Chi, Cammy Tsai, Kai Wen Ong, Sarah Su Tin Ho-Lim, Wei Wang

  20. Empagliflozin in the treatment of type 2 diabetes: evidence to date

    Directory of Open Access Journals (Sweden)

    Shubrook JH

    2015-10-01

    Full Text Available Jay H Shubrook,1 Babak Baradar Bokaie,2 Sarah E Adkins31Primary Care Department, Clinical Research and Diabetes Services, Touro University College of Osteopathic Medicine, Vallejo, CA, USA; 2The Diabetes Institute at Ohio University, Ohio University, Athens, OH, USA; 3Pharmacy Practice and Administration, College of Pharmacy, Ohio State University, Athens, OH, USA Abstract: In the last decade, researchers have gained a greater understanding of the pathophysiologic mechanisms of type 2 diabetes as a chronic and progressive disease. One of the more recent treatment targets is the kidney. The kidneys become maladaptive in diabetes by increasing the reabsorption of glucose above the normal physiologic renal threshold. This discovery has led to the development of the sodium/glucose cotransporter 2 inhibitors (SGLT2. These agents readjust the renal threshold for glucose reabsorption to a lower level and decrease glucose reabsorption, while increasing urinary glucose when the glucose is above the renal threshold and subsequently lowering plasma glucose. The mechanism of action of the SGLT2 inhibitors is insulin independent, which makes them a novel treatment of diabetes. At the time of preparation of this manuscript, there were three SGLT2 inhibitors available in the US. This manuscript focuses on empagliflozin, the newest SGLT2 inhibitor, the trials in its development, and the clinical data available to date. Further, the authors propose future applications of empagliflozin, including in the treatment of type 1 diabetes, and its potential role in renoprotection. Keywords: SGLT-2 inhibitors, empagliflozin, type 2 diabetes, kidneys, type 1 diabetes, glucosuria

  1. From bench to bedside: use of human adipose-derived stem cells

    Directory of Open Access Journals (Sweden)

    Feisst V

    2015-11-01

    Full Text Available Vaughan Feisst,1 Sarah Meidinger,1 Michelle B Locke2 1Dunbar Laboratory, School of Biological Sciences, 2Department of Surgery, Faculty of Medicine and Health Sciences, The University of Auckland, Auckland, New Zealand Abstract: Since the discovery of adipose-derived stem cells (ASC in human adipose tissue nearly 15 years ago, significant advances have been made in progressing this promising cell therapy tool from the laboratory bench to bedside usage. Standardization of nomenclature around the different cell types used is finally being adopted, which facilitates comparison of results between research groups. In vitro studies have assessed the ability of ASC to undergo mesenchymal differentiation as well as differentiation along alternate lineages (transdifferentiation. Recently, focus has shifted to the immune modulatory and paracrine effects of transplanted ASC, with growing interest in the ASC secretome as a source of clinical effect. Bedside use of ASC is advancing alongside basic research. An increasing number of safety-focused Phase I and Phase IIb trials have been published without identifying any significant risks or adverse events in the short term. Phase III trials to assess efficacy are currently underway. In many countries, regulatory frameworks are being developed to monitor their use and assure their safety. As many trials rely on ASC injected at a distant site from the area of clinical need, strategies to improve the homing and efficacy of transplanted cells are also being explored. This review highlights each of these aspects of the bench-to-bedside use of ASC and summarizes their clinical utility across a variety of medical specialties. Keywords: standardization, bystander effect, stromal cells, mesenchymal stem cells, stromal vascular fraction

  2. AbobotulinumtoxinA in the management of cervical dystonia in the United Kingdom: a budget impact analysis

    Directory of Open Access Journals (Sweden)

    Abogunrin S

    2015-09-01

    Full Text Available Seye Abogunrin,1 Sarah Brand,2 Kamal Desai,3 Jerome Dinet,4 Sylvie Gabriel,5 Timothy Harrower61Meta Research, Evidera, London, UK; 2Health Economics, Evidera, Bethesda, MD, USA; 3Health Economics, Evidera, London, UK; 4Health Economics and Outcomes Research (Global, 5Global Market Access and Pricing, Ipsen Pharma, Boulogne-Billancourt, France; 6Royal Devon and Exeter NHS Foundation Trust, Exeter, UKBackground: Cervical dystonia (CD can be effectively managed by a combination of botulinum neurotoxin A (BoNT-A and conventional therapy (skeletal muscle relaxants and rehabilitative therapy, but the costs of different interventions in the UK vary.Methods: A budget impact model was developed from the UK payer perspective with a 5-year time horizon to evaluate the effects of changing market shares of abobotulinumtoxinA, nabotulinumtoxinA, and incobotulinumtoxinA, and best supportive care from the UK payer perspective. Epidemiological and resource use data were retrieved from the published literature and clinical expert opinion. Deterministic sensitivity analyses were performed to determine the parameters most influential on the budgetary findings under base case assumptions.Results: Under base case assumptions, an increased uptake of abobotulinumtoxinA showed an accumulated savings of £2,250,992 by year 5. Treatment per patient per year with onabotulinumtoxinA and incobotulinumtoxinA costs more when compared to treatment with abobotulinumtoxinA. One-way sensitivity analyses showed that the prevalence of CD, dose per injection of each of the BoNT-As, and time to reinjection of incobotulinumtoxinA and abobotulinumtoxinA influenced the base case findings most.Conclusion: There is potential for cost savings associated with the greater use of abobotulinumtoxinA rather than other BoNT-A treatments, permitting more patients to benefit more from effective BoNT-A treatment with a fixed budget. Keywords: cervical dystonia, torticollis, botulinum toxin A, budget

  3. An Introduction to Thinking about Trustworthy Research into the Genetics of Intelligence.

    Science.gov (United States)

    Parens, Erik; Appelbaum, Paul S

    2015-01-01

    The advent of new technologies has rekindled some hopes that it will be possible to identify genetic variants that will help to explain why individuals are different with respect to complex traits. At least one leader in the development of "whole genome sequencing"-the Chinese company BGI-has been quite public about its commitment to using the technique to investigate the genetics of intelligence in general and high intelligence in particular. Because one needs large samples to detect the small effects associated with small genetic differences in the sequence of those base pairs, to make headway with the new sequencing technologies, one also needs to enlist much larger numbers of study participants than geneticists have enrolled before. In an effort to increase the size of a sample, one team of researchers approached the Center for Talented Youth at Johns Hopkins University. They wanted to gain access to records concerning participants in CTY's ongoing Study of Exceptional Talent, and they wanted to approach those individuals to see if they would be willing to share samples of their DNA. We agreed that CTY's dilemma about whether to give the researchers access to those records raised larger questions about the ethics of research into the genetics of intelligence, and we decided to hold a workshop at The Hastings Center that could examine those questions. Our purpose was to create what, borrowing from Sarah Richardson, we came to call a "transformative conversation" about research into the genetics of general cognitive ability-a conversation that would take a wide and long view and would involve a diverse group of stakeholders, including both people who have been highly critical of the research and people who engage in it. This collection of essays, which grew out of that workshop, is intended to provide an introduction to and exploration of this complex and important area. © 2015 The Hastings Center.

  4. Diverse circular replication-associated protein encoding viruses circulating in invertebrates within a lake ecosystem.

    Science.gov (United States)

    Dayaram, Anisha; Galatowitsch, Mark L; Argüello-Astorga, Gerardo R; van Bysterveldt, Katherine; Kraberger, Simona; Stainton, Daisy; Harding, Jon S; Roumagnac, Philippe; Martin, Darren P; Lefeuvre, Pierre; Varsani, Arvind

    2016-04-01

    Over the last five years next-generation sequencing has become a cost effective and efficient method for identifying known and unknown microorganisms. Access to this technique has dramatically changed the field of virology, enabling a wide range of environmental viral metagenome studies to be undertaken of organisms and environmental samples from polar to tropical regions. These studies have led to the discovery of hundreds of highly divergent single stranded DNA (ssDNA) virus-like sequences encoding replication-associated proteins. Yet, few studies have explored how viruses might be shared in an ecosystem through feeding relationships. Here we identify 169 circular molecules (160 CRESS DNA molecules, nine circular molecules) recovered from a New Zealand freshwater lake, that we have tentatively classified into 51 putatively novel species and five previously described species (DflaCV-3, -5, -6, -8, -10). The CRESS DNA viruses identified in this study were recovered from molluscs (Echyridella menzeisii, Musculium novaezelandiae, Potamopyrgus antipodarum and Physella acuta) and insect larvae (Procordulia grayi, Xanthocnemis zealandica, and Chironomus zealandicus) collected from Lake Sarah, as well as from the lake water and benthic sediments. Extensive diversity was observed across most CRESS DNA molecules recovered. The putative capsid protein of one viral species was found to be most similar to those of members of the Tombusviridae family, thus expanding the number of known RNA-DNA hybrid viruses in nature. We noted a strong association between the CRESS DNA viruses and circular molecules identified in the water and browser organisms (C. zealandicus, P. antipodarum and P. acuta), and between water sediments and undefended prey species (C. zealandicus). However, we were unable to find any significant correlation of viral assemblages to the potential feeding relationships of the host aquatic invertebrates. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Prader–Willi syndrome: clinical problems in transition from pediatric to adult care

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    Crinò A

    2016-07-01

    Full Text Available Antonino Crinò,1 Danilo Fintini,1 Sarah Bocchini,1 Chiara Carducci,1 Graziano Grugni,2 1Autoimmune Endocrine Diseases Unit, Bambino Gesù Children’s Hospital, Research Institute, Palidoro, Rome, 2Division of Auxology, Italian Auxological Institute, Research Institute, Piancavallo, Verbania, Italy Abstract: Prader–Willi syndrome (PWS represents the most common form of genetic obesity. Thanks to the advances in medical care and technology, many persons with PWS live longer and survive to adulthood. Currently, because of the many physical and behavioral manifestations, transitional health care is not easy for these patients and is considered a very important issue. Moreover, very few studies have examined these transitional problems in young adults with PWS. In recent years, there has been great interest in improving transition planning and support for young people with PWS reaching adulthood. In this article, we underline the main clinical problems in transition and give some advice to make this period less difficult and easier for adolescents with PWS. Special attention should be paid to obesity, diabetes mellitus, hypertension, osteoporosis, and sleep apnea during the period of transition. In PWS, for an effective transition from childhood to adulthood, a multidisciplinary team is needed, and should maintain the same approach to food, environment, and psychiatric issues. For comprehensive care, it is necessary to involve adult endocrinologists and other medical specialists in conjunction with the pediatric team. Parental involvement is, however, a great help for supervising adolescents with PWS during this particular period. Keywords: Prader–Willi, transition period, intellectual disabilities

  6. Layering of life (Sara novel of Peter Sarić

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    Kostić Dragomir J.

    2015-01-01

    Full Text Available Novel Sara of Petar Sarić consists of two parts; in it are processed or present two wars, two major wars in the region of Montenegro and Herzegovina, the First and Second World War. However, it is more novel about divisions within the family and the man himself, (and infamous assault of godfather Luka on Sarah also and his murder are in that function, in the first part; and on the divisions among the people, in general, in the second part of the novel. The second part is, in fact, the image layering of life, not a symbolic one, full of hope, faith, reliance, rather than a concrete, real life, that life which is transformed into a fear of life. Separate, poetical, part of the novel, is his main character, Sara. It is no coincidence that her name novel entitled. Because she is one of most beautiful characters in the newer Serbian prose. Speech about the Sara precedes speech about her book. The book is Sara, Sara's book! Possession of book is her main feature of the exterior. Sara comes out from the Book and disappears in the book. Self contained and independent, therefore doomed to conflict with the environment. Loyal to husband and family, loyal to the truth and for justice, she ,,not hurt anything and anyone, no one is standing in the way, to anyone not wroth, nor has anyone looked wrong.' At the same time, the strange beauty, beauty that could not fit into some sort of scheme, one particular image or idea of beauty that again and again renewed, changed, remaining distant, and unmet. Strange goodness, marvelous beauty, she suffered unusual way; her life was transformed into continuous abstinence, repression, in anxiety and fear. In a word: in martirizam! Finally, in order to safe­guard children, sacrificed herself. Novel is a strong critique of society which is not able to recognize the beauty / goodness!.

  7. Review of biphasic insulin aspart in the treatment of type 1 and 2 diabetes

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    Nazia Raja-Khan

    2008-01-01

    Full Text Available Nazia Raja-Khan, Sarah S Warehime, Robert A GabbayDivision of Endocrinology, Diabetes, and Metabolism, Penn State Institute for Diabetes and Obesity, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USABackground: Insulin is an effective treatment for achieving glycemic control and preventing complications in patients with diabetes. In order to make insulin therapy more acceptable to patients, newer formulations of insulin have been developed, such as biphasic insulins. Biphasic insulins conveniently provide both prandial and basal insulin in a single injection. One of the most well-studied biphasic insulins is biphasic insulin aspart 70/30.Objective: Our goal was to review the current literature on the safety and efficacy of biphasic insulin aspart in type 1 and type 2 diabetes.Methods: A MEDLINE search was conducted using the terms “biphasic insulin aspart” to identify clinical studies and reviews.Results: Biphasic insulin aspart more effectively reduces post-prandial glucose compared to other biphasic insulins and basal insulins. Compared to biphasic insulin aspart, fasting glucose levels are lower with NPH, similar with glargine, and similar or lower with biphasic human insulin. Treat-to-target trials have shown that a goal HbA1c below 6.5 or 7% can be achieved with biphasic insulin aspart. The risk of hypoglycemia is similar to or less than that seen with other biphasic insulins or NPH insulin.Conclusion: Biphasic insulin aspart 70/30 is a safe and effective treatment option for patients with diabetes.Keywords: biphasic insulin aspart, insulin, diabetes

  8. Treatment of fragile X-associated tremor ataxia syndrome (FXTAS and related neurological problems

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    Randi J Hagerman

    2008-06-01

    Full Text Available Randi J Hagerman1,2, Deborah A Hall3, Sarah Coffey1,2, Maureen Leehey3, James Bourgeois4, John Gould5, Lin Zhang6, Andreea Seritan4, Elizabeth Berry-Kravis7–9, John Olichney6, Joshua W Miller10, Amy L Fong11, Randall Carpenter12, Cathy Bodine13, Louise W Gane1,2, Edgar Rainin1, Hillary Hagerman1, Paul J Hagerman141M.I.N.D. Institute, 2Department of Pediatrics, 4Department of Psychiatry & Behavioral Sciences, 5Department of Urology, 6Department of Neurology, 10Department of Pathology and Laboratory Medicine, 14Department of Biochemistry and Molecular Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA; 3Department of Neurology, University of Colorado, Denver, CO, USA; 7Department of Pediatrics, Neurology, and Biochemistry, 8Department of Neurological Sciences, 9Department of Biochemistry, Rush University Medical Center, Chicago, IL, USA; 11Physical Edge, Inc., Davis, CA, USA; 12Seaside Therapeutics, Cambridge, MA, USA; 13Department of Physical Medicine and Rehabilitation, University of Colorado Health Sciences Center, Denver, CO, USAAbstract: Fragile X-associated tremor/ataxia syndrome (FXTAS is a progressive neurological disorder that affects older adult carriers, predominantly males, of premutation alleles (55 to 200 CGG repeats of the fragile X (FMR1 gene. Principal features of FXTAS are intention tremor, ataxia, parkinsonism, cognitive decline, and peripheral neuropathy; ancillary features include, autonomic dysfunction, and psychiatric symptoms of anxiety, depression, and disinhibition. Although controlled trials have not been carried out in individuals with FXTAS, there is a significant amount of anecdotal information regarding various treatment modalities. Moreover, there exists a great deal of evidence regarding the efficacy of various medications for treatment of other disorders (eg, Alzheimer disease that have substantial phenotypic overlap with FXTAS. The current review summarizes what is currently

  9. Spatio-temporal representativeness of ground-based downward solar radiation measurements

    Science.gov (United States)

    Schwarz, Matthias; Wild, Martin; Folini, Doris

    2017-04-01

    Surface solar radiation (SSR) is most directly observed with ground based pyranometer measurements. Besides measurement uncertainties, which arise from the pyranometer instrument itself, also errors attributed to the limited spatial representativeness of observations from single sites for their large-scale surrounding have to be taken into account when using such measurements for energy balance studies. In this study the spatial representativeness of 157 homogeneous European downward surface solar radiation time series from the Global Energy Balance Archive (GEBA) and the Baseline Surface Radiation Network (BSRN) were examined for the period 1983-2015 by using the high resolution (0.05°) surface solar radiation data set from the Satellite Application Facility on Climate Monitoring (CM-SAF SARAH) as a proxy for the spatiotemporal variability of SSR. By correlating deseasonalized monthly SSR time series form surface observations against single collocated satellite derived SSR time series, a mean spatial correlation pattern was calculated and validated against purely observational based patterns. Generally decreasing correlations with increasing distance from station, with high correlations (R2 = 0.7) in proximity to the observational sites (±0.5°), was found. When correlating surface observations against time series from spatially averaged satellite derived SSR data (and thereby simulating coarser and coarser grids), very high correspondence between sites and the collocated pixels has been found for pixel sizes up to several degrees. Moreover, special focus was put on the quantification of errors which arise in conjunction to spatial sampling when estimating the temporal variability and trends for a larger region from a single surface observation site. For 15-year trends on a 1° grid, errors due to spatial sampling in the order of half of the measurement uncertainty for monthly mean values were found.

  10. Modulation of the activity of N-methyl-D-aspartate receptors as a novel treatment option for depression: current clinical evidence and therapeutic potential of rapastinel (GLYX-13

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    Vasilescu AN

    2017-03-01

    Full Text Available Andrei-Nicolae Vasilescu,1,* Nina Schweinfurth,2,* Stefan Borgwardt,2,* Peter Gass,1 Undine E Lang,2,* Dragos Inta,1,2,* Sarah Eckart2,* 1Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany; 2Department of Psychiatry (Universitäre Psychiatrische Kliniken, University of Basel, Basel, Switzerland *These authors contributed equally to this work Abstract: Classical monoaminergic antidepressants show several disadvantages, such as protracted onset of therapeutic action. Conversely, the fast and sustained antidepressant effect of the N-methyl-d-aspartate receptor (NMDAR antagonist ketamine raises vast interest in understanding the role of the glutamate system in mood disorders. Indeed, numerous data support the existence of glutamatergic dysfunction in major depressive disorder (MDD. Drawback to this short-latency therapy is its side effect profile, especially the psychotomimetic action, which seriously hampers the common and widespread clinical use of ketamine. Therefore, there is a substantial need for alternative glutamatergic antidepressants with milder side effects. In this article, we review evidence that implicates NMDARs in the prospective treatment of MDD with focus on rapastinel (formerly known as GLYX-13, a novel synthetic NMDAR modulator with fast antidepressant effect, which acts by enhancing NMDAR function as opposed to blocking it. We summarize and discuss current clinical and animal studies regarding the therapeutic potential of rapastinel not only in MDD but also in other psychiatric disorders, such as obsessive–compulsive disorder and posttraumatic stress disorder. Additionally, we discuss current data concerning the molecular mechanisms underlying the antidepressant effect of rapastinel, highlighting common aspects as well as differences to ketamine. In 2016, rapastinel received the Breakthrough Therapy designation for the treatment

  11. Effects of the soil pore network architecture on the soil's physical functionalities

    Science.gov (United States)

    Smet, Sarah; Beckers, Eléonore; Léonard, Angélique; Degré, Aurore

    2017-04-01

    parameters uncertainties? Sarah Smet, as a research fellow, acknowledges the support of the National Fund for Scientific Research (Brussels, Belgium).

  12. An insight into light as a chronobiological therapy in affective disorders

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    Walsh JM

    2014-10-01

    Full Text Available Jacqueline M Walsh, Lynsey A Atkinson, Sarah A Corlett, Gurprit S Lall Medway School of Pharmacy, University of Kent, Chatham, Kent, UK Abstract: The field of chronobiology has vastly expanded over the past few decades, bringing together research from the fields of circadian rhythms and sleep. The importance of the environmental day–night cycle on our health is becoming increasingly evident as we evolve into a 24-hour society. Reducing or changing sleep times against our natural instincts to rest at night has a detrimental impact on our well-being. The mammalian circadian clock, termed "the suprachiasmatic nucleus", is responsible for synchronizing our behavioral and physiological outputs to the environment. It utilizes light transcoded by specialized retinal photoreceptors as its cue to set internal rhythms to be in phase with the light–dark cycle. Misalignment of these outputs results in symptoms such as altered/disturbed sleep patterns, changes in mood, and physical and mental exhaustion – symptoms shared by many affective clinical disorders. Key links to circadian abnormalities have been found in a number of disorders, such as seasonal affective disorder, nonseasonal depression, and bipolar affective disorder. Furthermore, therapies developed through chronobiological research have been shown to be beneficial in the treatment of these conditions. In this article, we discuss the impact of circadian research on the management of affective disorders, giving evidence of how a misaligned circadian system may be a contributor to the symptoms of depression and how moderating circadian rhythms with light therapy benefits patients. Keywords: circadian, depression, SAD, nonseasonal, bipolar

  13. Evaluation and management of pediatric hypertensive crises: hypertensive urgency and hypertensive emergencies

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    Patel NH

    2012-11-01

    Full Text Available Nirali H Patel,1 Sarah K Romero,2 David C Kaelber31Division of Emergency Medicine, Akron Children's Hospital, Akron, OH, USA; 2Division of Emergency Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH, USA; 3Departments of Information Services, Internal Medicine, Pediatrics, and Epidemiology and Biostatistics, The Center for Clinical Informatics Research and Education, The MetroHealth System and School of Medicine, Case Western Reserve University, Cleveland OH, USAAbstract: Hypertension (HTN in the pediatric population is estimated to have a world-wide prevalence of 2%-5%. As with adults, pediatric patients with HTN can present with hypertensive crises include hypertensive urgency and hypertensive emergencies. However, pediatric blood pressure problems have a greater chance of being from secondary causes of HTN, as opposed to primary HTN, than in adults. Thorough evaluation of a child with a hypertensive emergency includes accurate blood pressure readings, complete and focused symptom history, and appropriate past medical, surgical, and family history. Physical exam should include height, weight, four-limb blood pressures, a general overall examination and especially detailed cardiovascular and neurological examinations, including fundoscopic examination. Initial work-up should typically include electrocardiography, chest X-ray, serum chemistries, complete blood count, and urinalysis. Initial management of hypertensive emergencies generally includes the use of intravenous or oral antihypertensive medications, as well as appropriate, typically outpatient, follow-up. Emergency department goals for hypertensive crises are to (1 safely lower blood pressure, and (2 treat/minimize acute end organ damage, while (3 identifying underlying etiology. Intravenous antihypertensive medications are the treatment modality of choice for hypertensive emergencies with the goal of reducing systolic blood pressure by 25% of the original value over an 8

  14. Retreatments after multifocal intraocular lens implantation: an analysis

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    Gundersen KG

    2016-03-01

    Full Text Available Kjell Gunnar Gundersen,1 Sarah Makari,2 Steffen Ostenstad,1 Rick Potvin2 1Ifocus Eye Clinic, Haugesund, Norway; 2Science in Vision, Akron, NY, USA Purpose: To determine the incidence and etiology of required retreatment after multifocal intraocular lens (IOL implantation and to evaluate the methods and clinical outcomes of retreatment.Patients and methods: A retrospective chart review of 416 eyes of 209 patients from one site that underwent uncomplicated cataract surgery with multifocal IOL implantation. Biometry, the IOL, and refractive data were recorded after the original implantation, with the same data recorded after retreatment. Comments related to vision were obtained both before and after retreatment for retreated patients.Results: The multifocal retreatment rate was 10.8% (45/416 eyes. The eyes that required retreatment had significantly higher residual refractive astigmatism compared with those who did not require retreatment (1.21±0.51 D vs 0.51±0.39 D, P<0.01. The retreatment rate for the two most commonly implanted primary IOLs, blended bifocal (10.5%, 16/152 and bilateral trifocal (6.9%, 14/202 IOLs, was not statistically significantly different (P=0.12. In those requiring retreatment, refractive-related complaints were most common. Retreatment with refractive corneal surgery, in 11% of the eyes, and piggyback IOLs, in 89% of the eyes, was similarly successful, improving patient complaints 78% of the time.Conclusion: Complaints related to ametropia were the main reasons for retreatment. Residual astigmatism appears to be an important determinant of retreatment rate after multifocal IOL implantation. Retreatment can improve symptoms for a high percentage of patients; a piggyback IOL is a viable retreatment option. Keywords: piggyback IOL, Sulcoflex, toric, STAAR, symptoms, astigmatism

  15. Mindfulness training applied to addiction therapy: insights into the neural mechanisms of positive behavioral change

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    Garl

    2016-07-01

    Full Text Available Eric L Garland,1,2 Matthew O Howard,3 Sarah E Priddy,1 Patrick A McConnell,4 Michael R Riquino,1 Brett Froeliger4 1College of Social Work, 2Hunstsman Cancer Institute, University of Utah, Salt Lake City, UT, USA; 3School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 4Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA Abstract: Dual-process models from neuroscience suggest that addiction is driven by dysregulated interactions between bottom-up neural processes underpinning reward learning and top-down neural functions subserving executive function. Over time, drug use causes atrophy in prefrontally mediated cognitive control networks and hijacks striatal circuits devoted to processing natural rewards in service of compulsive seeking of drug-related reward. In essence, mindfulness-based interventions (MBIs can be conceptualized as mental training programs for exercising, strengthening, and remediating these functional brain networks. This review describes how MBIs may remediate addiction by regulating frontostriatal circuits, thereby restoring an adaptive balance between these top-down and bottom-up processes. Empirical evidence is presented suggesting that MBIs facilitate cognitive control over drug-related automaticity, attentional bias, and drug cue reactivity, while enhancing responsiveness to natural rewards. Findings from the literature are incorporated into an integrative account of the neural mechanisms of mindfulness-based therapies for effecting positive behavior change in the context of addiction recovery. Implications of our theoretical framework are presented with respect to how these insights can inform the addiction therapy process. Keywords: mindfulness, frontostriatal, savoring, cue reactivity, hedonic dysregulation, reward, addiction

  16. The Steins and the Hungarians

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    Barki, Gergely

    2014-05-01

    Full Text Available The traveling exhibition entitled "The Steins Collect" (2011-12 again drew attention – and on this occasion in a manner perhaps more vivid than any exhibition to date – to the importance of the systematically canon-shaping work that took place in two tiny Parisian ateliers (one in the Rue de Fleurus, the other in the Rue de Madame in terms of the new painterly movements that emerged at the beginning of the 20th century. Leo, Gertrude, and Michael, three siblings from the Stein family, a family of Jewish origin from San Francisco, along with Michael's wife Sarah, not only built within the space of a few years the most important contemporary art collection in Paris, but through their lively salons came to be the most influential shapers and propagators of universal modernism, making their influence felt to this day on assessments of avant-garde art. In the course of preparations for the exhibition and the publication of the accompanying catalogue, both of which provide a comprehensive survey of the Steins' activity, light was cast on the family's Hungarian connections as well. Consequently, one painting by the Hungarian Vilmos Pelrott-Csaba was included at the American venues (San Francisco and New York of the exhibition, and a presentation on the family's ties to Hungary was held at the scholarly conference organized in connection with the exhibition. Despite the fact that several essays have been published on this subject, the written sources have not been collected – neither those dealing with the large number of Hungarians present at the Steins' Saturday evening gatherings, nor those covering the Hungarian pupils at the Académie Matisse, which was closely aligned with the Steins. This essay is a revised version of the presentation held at the Metropolitan Museum of Art in New York, supplemented with additional source-material.

  17. Diagnosis and management of food allergies: new and emerging options: a systematic review

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    O’Keefe AW

    2014-10-01

    Full Text Available Andrew W O'Keefe,1,2 Sarah De Schryver,1 Jennifer Mill,3 Christopher Mill,3 Alizee Dery,1 Moshe Ben-Shoshan1 1Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada; 2Department of Pediatrics, Faculty of Medicine, Memorial University of Newfoundland, St John's, NL, Canada; 3Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada Abstract: It is reported that 6% of children and 3% of adults have food allergies, with studies suggesting increased prevalence worldwide over the last few decades. Despite this, our diagnostic capabilities and techniques for managing patients with food allergies remain limited. We have conducted a systematic review of literature published within the last 5 years on the diagnosis and management of food allergies. While the gold standard for diagnosis remains the double-blind, placebo-controlled food challenge, this assessment is resource intensive and impractical in most clinical situations. In an effort to reduce the need for the double-blind, placebo-controlled food challenge, several risk-stratifying tests are employed, namely skin prick testing, measurement of serum-specific immunoglobulin E levels, component testing, and open food challenges. Management of food allergies typically involves allergen avoidance and carrying an epinephrine autoinjector. Clinical research trials of oral immunotherapy for some foods, including peanut, milk, egg, and peach, are under way. While oral immunotherapy is promising, its readiness for clinical application is controversial. In this review, we assess the latest studies published on the above diagnostic and management modalities, as well as novel strategies in the diagnosis and management of food allergy. Keywords: skin prick testing, oral challenge, specific IgE, component testing, oral immunotherapy, epinephrine

  18. A Peer-Led Electronic Mental Health Recovery App in an Adult Mental Health Service: Study Protocol for a Pilot Trial.

    Science.gov (United States)

    Gulliver, Amelia; Banfield, Michelle; Reynolds, Julia; Miller, Sarah; Galati, Connie; Morse, Alyssa R

    2017-12-07

    There is growing demand for peer workers (people who use their own lived experience to support others in their recovery) to work alongside consumers to improve outcomes and recovery. Augmenting the workforce with peer workers has strong capacity to enhance mental health and recovery outcomes and make a positive contribution to the workforce within mental health systems and to the peer workers themselves. Technology-based applications are highly engaging and desirable methods of service delivery. This project is an exploratory proof-of-concept study, which aims to determine if a peer worker-led electronic mental (e-mental) health recovery program is a feasible, acceptable, and effective adjunct to usual treatment for people with moderate to severe mental illness. The study design comprises a recovery app intervention delivered by a peer worker to individual consumers at an adult mental health service. Evaluation measures will be conducted at post-intervention. To further inform the acceptability and feasibility of the model, consumers will be invited to participate in a focus group to discuss the program. The peer worker, peer supervisor, and key staff at the mental health service will also be individually interviewed to further evaluate the feasibility of the program within the health service and further inform its future development. The program will be delivered over a period of approximately 4 months, commencing June 2017. If the peer worker-led recovery app is found to be feasible, acceptable, and effective, it could be used to improve recovery in mental health service consumers. ©Amelia Gulliver, Michelle Banfield, Julia Reynolds, Sarah Miller, Connie Galati, Alyssa R Morse. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 07.12.2017.

  19. Entrevista a Sherry Ortner

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    Sergio Daniel López

    2006-01-01

    Full Text Available Una histórica fotografía de Franz Boas interpretando una danza ceremonial kwakiutl y La Declaración Universal de los Derechos Humanos, dan la bienvenida al despacho de Sherry Beth Ortner, en el Departamento de Antropología de la Universidad de California, Los Angeles (UCLA. Doctora en antropología por la Universidad de Chicago, Sherry Ortner trabajó durante gran parte de su carrera con los sherpas, en Nepal. La publicación de su artículo “¿Es la mujer con respecto al hombre lo que la naturaleza con respecto a la cultura?” en 1972, marcó un antes y un después en la antropología académica feminista y en los estudios de género. Ortner ha sido profesora en el Sarah Lawrence College, en la Universidad de California, Berkeley, en la Universidad de Columbia y dirigió el Departamento de Antropología de la Universidad de Michigan. Actualmente es Profesora Honoraria de UCLA, donde imparte cursos sobre imaginación etnográfica y teoría social crítica. En esta entrevista le hemos preguntado sobre sus distintas etapas investigadoras, desde sus primeros trabajos de campo hasta su actual investigación sobre la industria cinematográfica en Hollywood, pasando por su relación con la antropología feminista y sus trabajos sobre capitalismo y cambio social. Sherry Ortner es una antropóloga alegre, muy cordial, inquieta y capaz de captar en todo momento el pulso de la sociedad occidental a través de sus obras.

  20. Archaeology 2.0? Review of Archaeology 2.0: New Approaches to Communication and Collaboration [Web Book

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    Michael Shanks

    2012-10-01

    Full Text Available The Cotsen Institute in Los Angeles has launched a new publishing initiative in 'Digital Archaeology'. Its first book, Archaeology 2.0: New Approaches to Communication and Collaboration, edited by Eric C. Kansa, Sarah Whitcher Kansa and Ethan Watrall, makes a grand claim, if only in its title, that archaeology has undergone, or is about to undergo, changes that bring about a completely new version or kind of archaeology. The analogy is with the World Wide Web. Just as the IT world embraced radical changes of software design and web delivery nearly ten years ago and announced that this was Web version 2.0, so too archaeology is changed, the authors claim, and enough to warrant the designation version 2.0. We disagree and argue that the claim is not well supported. Moreover, we hold that the book misunderstands the implications of Web 2.0 and its aftermath. The well-meaning authors do make a valuable contribution to debates about uses of information technology in archaeology, and particularly data management. But their perspective is hopelessly narrow, looking back to the circumscribed concerns of professional field archaeologists with their data, its dissemination, use and survival. The authors focus mainly upon their own projects, expressing little interest in the scope of contemporary archaeology, digitally enabled as it all is, through heritage and everything to do with the representation of the material past in the present, an interest surely begged by the overt reference to the global changes associated with the notion of Web 2.0.

  1. The employment of imagination in the performance of the Iraqi theater actor توظيف الخيال في اداء الممثل المسرحي العراقي

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    Dr. Ali Abdul Mohsen Ali د.علي عبد المحسن علي

    2015-01-01

    Full Text Available Fantasy have been Taking ample space of the concerns of philosophers and critics and get inside the way people think and mythology and myths, customs and religions, because the element engine of the interaction of those people with the world and interact with other people, so the importance of the fantasy element of the achievements of scientists, artists, each according to the exact competence, and therefore Imagination generates creativity and innovation. Not for the imagination to enable the Einstein of Anjar theory of relativity, which is a simple equation, but not fantasy element to enable Beethoven composed by the magnificent symphony (Symphony of Beethoven, and Vaknr well as through authored many books based on the so - called (melody signifier ​​as well as with Jaykovski -authored to cut (Swan Lake, and when he managed to Dostoyevsky and Tolstoy written stories that carry a global character mimic the actions of its characters actions figures from every time and place. Imagination also enters the myths and beliefs of everyday peoples and enters as well as in the poetic side, which relies on self-expression through the poetic image expressive, and enters as well as in the works of drama authors the likes of Shakespeare and Ibsen and Chekhov, and enters the imagination as well as in the work of directors, playwrights like Stanislavski and Maarjuld and Peter Brook and Fajtankov and Brecht , not fiction stands at this point but included representatives work the likes of Charlie Chaplin and David Garrick and Sarah Bernard and Antonio Quinn, so the researcher coined the title for his research was in the form of a question you can employ in the performance of the theatrical imagination Representative of Iraq?

  2. Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS

    Directory of Open Access Journals (Sweden)

    Badowski ME

    2016-02-01

    Full Text Available Melissa E Badowski,1 Sarah E Perez2 1Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; 2Infectious Diseases Clinic, Tufts Medical Center, Boston, MA, USA Abstract: Since the beginning of the HIV/AIDS epidemic, weight loss has been a common complaint for patients. The use of various definitions defining HIV wasting syndrome has made it difficult to determine its actual prevalence. Despite the use of highly active antiretroviral therapy, it is estimated that the prevalence of HIV wasting syndrome is between 14% and 38%. HIV wasting syndrome may stem from conditions affecting chewing, swallowing, or gastrointestinal motility, neurologic disease affecting food intake or the perception of hunger or ability to eat, psychiatric illness, food insecurity generated from psychosocial or economic concerns, or anorexia due to medications, malabsorption, infections, or tumors. Treatment of HIV wasting syndrome may be managed with appetite stimulants (megestrol acetate or dronabinol, anabolic agents (testosterone, testosterone analogs, or recombinant human growth hormone, or, rarely, cytokine production modulators (thalidomide. The goal of this review is to provide an in-depth evaluation based on existing clinical trials on the clinical utility of dronabinol in the treatment of weight loss associated with HIV/AIDS. Although total body weight gain varies with dronabinol use (–2.0 to 3.2 kg, dronabinol is a well-tolerated option to promote appetite stimulation. Further studies are needed with standardized definitions of HIV-associated weight loss and clinical outcomes, robust sample sizes, safety and efficacy data on chronic use of dronabinol beyond 52 weeks, and associated virologic and immunologic outcomes. Keywords: dronabinol, weight loss, HIV/AIDS, HIV wasting syndrome, cachexia

  3. Exploring the Role of In-Person Components for Online Health Behavior Change Interventions: Can a Digital Person-to-Person Component Suffice?

    Science.gov (United States)

    Santarossa, Sara; Kane, Deborah; Senn, Charlene Y; Woodruff, Sarah J

    2018-04-11

    The growth of the digital environment provides tremendous opportunities to revolutionize health behavior change efforts. This paper explores the use of Web-based, mobile, and social media health behavior change interventions and determines whether there is a need for a face-to-face or an in-person component. It is further argued that that although in-person components can be beneficial for online interventions, a digital person-to-person component can foster similar results while dealing with challenges faced by traditional intervention approaches. Using a digital person-to-person component is rooted in social and behavioral theories such as the theory of reasoned action, and the social cognitive theory, and further justified by the human support constructs of the model of supportive accountability. Overall, face-to-face and online behavior change interventions have their respective advantages and disadvantages and functions, yet both serve important roles. It appears that it is in fact human support that is the most important component in the effectiveness and adherence of both face-to-face and online behavior change interventions, and thoughtfully introducing a digital person-to-person component, to replace face-to-face interactions, can provide the needed human support while diminishing the barriers of in-person meetings. The digital person-to-person component must create accountability, generate opportunities for tailored feedback, and create social support to successfully create health behavior change. As the popularity of the online world grows, and the interest in using the digital environment for health behavior change interventions continues to be embraced, further research into not only the use of online interventions, but the use of a digital person-to-person component, must be explored. ©Sara Santarossa, Deborah Kane, Charlene Y Senn, Sarah J Woodruff. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.04.2018.

  4. William E. Vidaver (1921-2017): an innovator, enthusiastic scientist, inspiring teacher and a wonderful friend.

    Science.gov (United States)

    Burr, A H Jay; Vidaver, Aaron; Schreiber, Ulrich; Bruce, Doug; Donnelly, Danielle J

    2018-06-01

    William (Bill) E. Vidaver (February 2, 1921-August 31, 2017), who did his Ph.D. with Laurence (Larry) R. Blinks at Stanford (1964) and a postdoc with C. Stacy French (1965), taught and did research at Simon Fraser University (SFU) for almost 30 years. Here he published over 80 papers in photosynthesis-related areas co-authored by his graduate students, postdocs, visiting professors and SFU colleagues. He developed a unique high-pressure cuvette for the study of oxygen exchange and studied high-pressure effects in photosynthesis. Ulrich (Uli) Schreiber, as a postdoctoral fellow from Germany, introduced measurements on chlorophyll (Chl) a fluorescence to Bill's lab, leading to the discovery of reversible inhibition of excitation energy transfer between photosynthetic pigments and of a pivotal role of O 2 in the oxidation of the electron transport chain between Photosystem II (PS II) and PS I. Bill's and Uli's work led to a patent of a portable chlorophyll fluorometer, the first available commercially, which was later modified to measure whole plantlets. The latter was used in pioneering measurement of the health of forest and crop plants undergoing in vitro clonal micropropagation. With several other researchers (including Doug Bruce, the late Radovan Popovic, and Sarah Swenson), he localized the quenching site of O 2 and showed a dampening effect on measurements of the four-step process of O 2 production by endogenous oxygen uptake. Bill is remembered as a hard-working but fun-loving person with a keen mind and strong sense of social justice.

  5. Fish the ChIPs: a pipeline for automated genomic annotation of ChIP-Seq data

    Directory of Open Access Journals (Sweden)

    Minucci Saverio

    2011-10-01

    Shpakovski and Sarah Teichmann.

  6. A Political Case of Penetrating Cranial Trauma: The Injury of James Scott Brady.

    Science.gov (United States)

    Menger, Richard; Kalakoti, Piyush; Hanif, Rimal; Ahmed, Osama; Nanda, Anil; Guthikonda, Bharat

    2017-09-01

    James Brady, the White House press secretary during President Ronald Reagan's first term in office, was 1 of 4 people (including the President) wounded during an attempted assassination attempt on President Reagan's life on March 30, 1981. John Hinckley, Jr. was found not guilty of this attempt by reason of insanity. The assassination attempt was a ploy by Hinckley, Jr. to impress the actress Jodie Foster. Brady was the most seriously injured of the 4 who were wounded. He suffered a gunshot wound to the left forehead that traveled through the left frontal lobe, corpus callosum, and then into the right frontal and temporal lobes. He initially required a bifrontal craniotomy for evacuation of a right frontotemporal intraparenchymal hemorrhage and debridement of tract. His postoperative course was complicated by seizures, cerebrospinal fluid leakage (necessitating multiple reparative procedures), aspiration pneumonia, and pulmonary emboli. Despite the severity of his injury and perioperative morbidities, Mr. Brady made good recovery. Although permanently left with residual weakness on the left side of his body, making a wheelchair necessary, Brady maintained cognitive and personality traits that were very close to his preinjury baseline. As a result, James Brady and his wife, Sarah, led a call to create legislative reform subsequently known as the "Brady Bill." This bill controversially made mandatory background checks for the purchase of firearms from licensed dealers. Our work aims to describe the assassination attempt, the neurosurgical injury and management of Mr. Brady's case, and the brief historical sequel that followed. Copyright © 2017 by the Congress of Neurological Surgeons.

  7. The eXtraordinarY Kids Clinic: an interdisciplinary model of care for children and adolescents with sex chromosome aneuploidy

    Directory of Open Access Journals (Sweden)

    Tartaglia N

    2015-07-01

    Full Text Available Nicole Tartaglia,1,2 Susan Howell,1,2 Rebecca Wilson,2 Jennifer Janusz,1,2 Richard Boada,1,2 Sydney Martin,2 Jacqueline B Frazier,2 Michelle Pfeiffer,2 Karen Regan,2 Sarah McSwegin,2 Philip Zeitler1,2 1Department of Pediatrics, University of Colorado School of Medicine, 2Child Development Unit, Children's Hospital Colorado, Aurora, CO, USA Purpose: Individuals with sex chromosome aneuploidies (SCAs are born with an atypical number of X and/or Y chromosomes, and present with a range of medical, developmental, educational, behavioral, and psychological concerns. Rates of SCA diagnoses in infants and children are increasing, and there is a need for specialized interdisciplinary care to address associated risks. The eXtraordinarY Kids Clinic was established to provide comprehensive and experienced care for children and adolescents with SCA, with an interdisciplinary team composed of developmental–behavioral pediatrics, endocrinology, genetic counseling, child psychology, pediatric neuropsychology, speech–language pathology, occupational therapy, nursing, and social work. The clinic model includes an interdisciplinary approach to care, where assessment results by each discipline are integrated to develop unified diagnostic impressions and treatment plans individualized for each patient. Additional objectives of the eXtraordinarY Kids Clinic program include prenatal genetic counseling, research, education, family support, and advocacy. Methods: Satisfaction surveys were distributed to 496 patients, and responses were received from 168 unique patients. Results: Satisfaction with the overall clinic visit was ranked as “very satisfied” in 85%, and as “satisfied” in another 9.8%. Results further demonstrate specific benefits from the clinic experience, the importance of a knowledgeable clinic coordinator, and support the need for similar clinics across the country. Three case examples of the interdisciplinary approach to assessment and

  8. Safety analysis and risk assessment handbook

    International Nuclear Information System (INIS)

    Peterson, V.L.; Colwell, R.G.; Dickey, R.L.

    1997-01-01

    This Safety Analysis and Risk Assessment Handbook (SARAH) provides guidance to the safety analyst at the Rocky Flats Environmental Technology Site (RFETS) in the preparation of safety analyses and risk assessments. Although the older guidance (the Rocky Flats Risk Assessment Guide) continues to be used for updating the Final Safety Analysis Reports developed in the mid-1980s, this new guidance is used with all new authorization basis documents. With the mission change at RFETS came the need to establish new authorization basis documents for its facilities, whose functions had changed. The methodology and databases for performing the evaluations that support the new authorization basis documents had to be standardized, to avoid the use of different approaches and/or databases for similar accidents in different facilities. This handbook presents this new standardized approach. The handbook begins with a discussion of the requirements of the different types of authorization basis documents and how to choose the one appropriate for the facility to be evaluated. It then walks the analyst through the process of identifying all the potential hazards in the facility, classifying them, and choosing the ones that need to be analyzed further. It then discusses the methods for evaluating accident initiation and progression and covers the basic steps in a safety analysis, including consequence and frequency binning and risk ranking. The handbook lays out standardized approaches for determining the source terms of the various accidents (including airborne release fractions, leakpath factors, etc.), the atmospheric dispersion factors appropriate for Rocky Flats, and the methods for radiological and chemical consequence assessments. The radiological assessments use a radiological open-quotes templateclose quotes, a spreadsheet that incorporates the standard values of parameters, whereas the chemical assessments use the standard codes ARCHIE and ALOHA

  9. Intrinsic Uncertainties in Modeling Complex Systems.

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, Curtis S; Bramson, Aaron L.; Ames, Arlo L.

    2014-09-01

    Models are built to understand and predict the behaviors of both natural and artificial systems. Because it is always necessary to abstract away aspects of any non-trivial system being modeled, we know models can potentially leave out important, even critical elements. This reality of the modeling enterprise forces us to consider the prospective impacts of those effects completely left out of a model - either intentionally or unconsidered. Insensitivity to new structure is an indication of diminishing returns. In this work, we represent a hypothetical unknown effect on a validated model as a finite perturba- tion whose amplitude is constrained within a control region. We find robustly that without further constraints, no meaningful bounds can be placed on the amplitude of a perturbation outside of the control region. Thus, forecasting into unsampled regions is a very risky proposition. We also present inherent difficulties with proper time discretization of models and representing in- herently discrete quantities. We point out potentially worrisome uncertainties, arising from math- ematical formulation alone, which modelers can inadvertently introduce into models of complex systems. Acknowledgements This work has been funded under early-career LDRD project #170979, entitled "Quantify- ing Confidence in Complex Systems Models Having Structural Uncertainties", which ran from 04/2013 to 09/2014. We wish to express our gratitude to the many researchers at Sandia who con- tributed ideas to this work, as well as feedback on the manuscript. In particular, we would like to mention George Barr, Alexander Outkin, Walt Beyeler, Eric Vugrin, and Laura Swiler for provid- ing invaluable advice and guidance through the course of the project. We would also like to thank Steven Kleban, Amanda Gonzales, Trevor Manzanares, and Sarah Burwell for their assistance in managing project tasks and resources.

  10. Development of the Oxford Participation and Activities Questionnaire: constructing an item pool

    Directory of Open Access Journals (Sweden)

    Kelly L

    2015-05-01

    Full Text Available Laura Kelly, Crispin Jenkinson, Sarah Dummett, Jill Dawson, Ray Fitzpatrick, David Morley Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK Purpose: The Oxford Participation and Activities Questionnaire is a patient-reported outcome measure in development that is grounded on the World Health Organization International Classification of Functioning, Disability, and Health (ICF. The study reported here aimed to inform and generate an item pool for the new measure, which is specifically designed for the assessment of participation and activity in patients experiencing a range of health conditions. Methods: Items were informed through in-depth interviews conducted with 37 participants spanning a range of conditions. Interviews aimed to identify how their condition impacted their ability to participate in meaningful activities. Conditions included arthritis, cancer, chronic back pain, diabetes, motor neuron disease, multiple sclerosis, Parkinson's disease, and spinal cord injury. Transcripts were analyzed using the framework method. Statements relating to ICF themes were recast as questionnaire items and shown for review to an expert panel. Cognitive debrief interviews (n=13 were used to assess items for face and content validity. Results: ICF themes relevant to activities and participation in everyday life were explored, and a total of 222 items formed the initial item pool. This item pool was refined by the research team and 28 generic items were mapped onto all nine chapters of the ICF construct, detailing activity and participation. Cognitive interviewing confirmed the questionnaire instructions, items, and response options were acceptable to participants. Conclusion: Using a clear conceptual basis to inform item generation, 28 items have been identified as suitable to undergo further psychometric testing. A large-scale postal survey will follow in order to refine the instrument further and

  11. Barriers and enablers of physical activity engagement for patients with COPD in primary care

    Directory of Open Access Journals (Sweden)

    Kosteli MC

    2017-03-01

    Full Text Available Maria-Christina Kosteli,1 Nicola R Heneghan,1 Carolyn Roskell,1 Sarah E Williams,1 Peymane Adab,2 Andrew P Dickens,2 Alexandra Enocson,2 David A Fitzmaurice,2 Kate Jolly,2 Rachel Jordan,2 Sheila Greenfield,2 Jennifer Cumming1 1School of Sport, Exercise and Rehabilitation Sciences, 2Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham, UK Background: Given that physical activity (PA has a positive impact on COPD symptoms and prognosis, this study examined the factors that both encourage and limit participation in PA for individuals with COPD in a primary care setting from the perspective of social cognitive theory.Methods: A purposive sample of 26 individuals with a range of COPD severity (age range: 50–89 years; males =15 were recruited from primary care to participate in one of four focus groups. Thematic analysis was undertaken to identify key concepts related to their self-efficacy beliefs.Results: Several barriers and enablers closely related to self-efficacy beliefs and symptom severity were identified. The main barriers were health related (fatigue, mobility problems, breathing issues caused by the weather, psychological (embarrassment, fear, frustration/disappointment, attitudinal (feeling in control of their condition, PA perception, older age perception, and motivational. The main enabling factors were related to motivation (autonomous or controlled, attitudes, self-regulation, and performance accomplishments.Clinical implications: When designing interventions for individuals with COPD, it is important to understand the patient-specific social cognitive influences on PA participation. This information can then inform individually tailored management planning. Keywords: COPD, social cognitive theory, self-efficacy, barriers, enablers, primary care

  12. Cartography teaching and the development of spatial thinking in Brazilian geography textbooks

    Science.gov (United States)

    Duarte, Ronaldo G.

    2018-05-01

    Spatial thinking has been recognized as closely related to tools of representation (NRC, 2006) and the maps have been widely pointed out as crucial for the development of that kind of reasoning. Furthermore, the scientific com-munity dedicated to the field of the spatial thinking has been asserting that the abilities encompassed in such a complex cognition can and must be fostered in school. Considering these groundwork, our research focused on the decision to assess the effectiveness of the contribution for the development of student's spatial thinking, provided by the questions found in Brazilian middle school geography textbooks. The main concern was the proficiency regarding cartographic language. To assure the possibility of comparing our results with some other investigations we decided to use a methodology that was strongly based on the Taxonomy of Spatial Thinking, designed by Injeong Jo and Sarah Bednarz (2009). Counting on those powerful tools we analyzed 6.884 questions in the three most adopted geography textbooks sets in Brazilian middle schools (6th, 7th, 8th and 9th grades). For the purpose of enlarging the number of books and countries to be compared, we have also evaluated 2.073 questions that are present in a French geography textbook set edited for the same grades. Using the taxonomy enabled us not only to evaluate if the questions demanded or not the use of the spatial thinking by the students. It also showed us the three general levels of reasoning involved, allowing to discern between low, intermediate and high levels of spatial thinking.

  13. Factors associated with continuing emergence of β-thalassemia major despite prenatal testing: a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Al Sabbah H

    2017-09-01

    Full Text Available Haleama Al Sabbah,1 Sarah Khan,1 Abdallah Hamadna,2 Lamia Abu Ghazaleh,2 Anwar Dudin,2 Bashar Adnan Karmi3 1College of Natural and Health Sciences, Zayed University, Dubai, UAE; 2Faculty of Medicine, An-Najah National University, Nablus, Palestine; 3Thalassemia Patients’ Friends Society, Ramallah, Palestine Purpose: Health care initiatives focusing on prenatal testing and premarital genetic screening aiming to reduce the incidence of β-thalassemia have emerged during the last decade. In Palestine, 4% of the population are known thalassemia carriers with new cases continuing to appear despite the availability of prenatal testing. This study aims to identify factors that influence the decision to retain or abort fetuses affected by β-thalassemia in Palestine. Methods: Convenience sampling was used to select 32 women (72 fetuses who were at risk of having a baby with β-thalassemia. A questionnaire on prenatal testing, test results, pregnancy outcomes, and factors influencing the decision to terminate the pregnancy were used for this cross-sectional study. The data were analyzed using SPSS version 17. Results: Among the fetuses screened, 36 (50% were thalassemia carriers and 20 (28% had β-thalassemia; 17 (85% affected fetuses were aborted. Religious beliefs were the most cited reason for opposing abortion while prior experience with β-thalassemia patients and awareness programs promoted abortions. Mothers who opted to retain an affected fetus had modest educational attainment. Higher educational level was significantly associated with the decision to abort an affected fetus (p<0.05. Conclusion: A religious consensus is needed on the abortion of fetuses affected by β-thalassemia. Improving female education and increasing awareness on thalassemia could help reduce the incidence of β-thalassemia in Palestine and around the world. Keywords: abortion, Islam, fetus, awareness

  14. Messages on pregnancy and family planning that providers give women living with HIV in the context of a Positive Health, Dignity, and Prevention intervention in Mozambique

    Directory of Open Access Journals (Sweden)

    Hilliard S

    2014-12-01

    Full Text Available Starr Hilliard, Sarah A Gutin, Carol Dawson Rose Department of Community Health Systems, School of Nursing, University of California at San Francisco, San Francisco, CA, USA Background: Family planning is an important HIV prevention tool for women living with HIV (WLHIV. In Mozambique, the prevalence of HIV among women of reproductive age is 13.1% and the average fertility rate is high. However, family planning and reproductive health for WLHIV are under-addressed in Mozambique. This study explores provider descriptions of reproductive health messages in order to identify possible barriers and facilitators to successfully addressing family planning and pregnancy concerns of WLHIV. Methods: In 2006, a Positive Health, Dignity, and Prevention program was introduced in Mozambique focused on training health care providers to work with patients to reduce their transmission risks. Providers received training on multiple components, including family planning and prevention of mother-to-child transmission (PMTCT. In-depth interviews were conducted with 31 providers who participated in the training in five rural clinics in three provinces. Data were analyzed using qualitative content analysis. Results: Analysis showed that providers' clinical messages on family planning, pregnancy, and PMTCT for WLHIV could be arranged along a continuum. Provider statements ranged from saying that WLHIV should not become pregnant and condoms are the only valid form of family planning for WLHIV, to suggesting that WLHIV can have safe pregnancies. Conclusion: These data indicate that many providers continue to believe that WLHIV should not have children and this represents a challenge for integrating family planning into the care of WLHIV. Also, not offering WLHIV a full selection of family planning methods severely limits their ability to protect themselves from unintended pregnancies and to fully exercise their reproductive rights. Responding to the reproductive health

  15. Advance in the Study of the Mechanisms Regulated by Sphingosine-1-Phosphate

    Science.gov (United States)

    Ye, Fei; Kong, Xiangqian; Luo, Cheng

    2010-09-01

    Sphingosine-1-phosphate (S1P) is a bioactive lipid messenger in the cells that regulate gene expression and NF-KB signal pathway through unknown mechanisms. Recently, Cheng Luo, associate professor of DDDC in Shanghai Institute of Materia Medica, whose project was funded by the National Natural Science Foundation of China, joined in a research team led by Professor Sarah Spiegel of Virginia Commonwealth University. The team continuously made significant breakthroughs in understanding the regulation mechanism of Sphingosine-1-Phosphate. In September 2009, in a paper published on SCIENCE magazine (Science 2009, 325: 1254-7), they firstly demonstrated that S1P is a physiologically important regulator of histone deacetylases (HDACs), HDACs are direct intracellular targets of S1P. Furthermore, they identified the mechanism that S1P regulates gene expression through regulating the activity of HDACs. In June 24th, 2010, in another paper to be published on NATURE magazine (Nature 2010, June 24th, advance online publication) which reports the regulation of NF-KB signaling pathway by S1P. They demonstrate that S1P is the missing cofactor for TRAF2 (tumour-necrosis factor receptor-associated factor 2) and indicate a new paradigm for the regulation of lysine-63-linked poly-ubiquitination. The study also highlight the key role of SphK1 and its product S1P in TNF-α signalling and the canonical NF-KB activation pathway, and then play crucial role in inflammatory, antiapoptotic and immune processes. The identification of new mechanisms by which S1P regulates gene expression and TNF and NF-KB signaling pathway will light up the road to develop novel inhibitors that might be useful for treatment of cancer and inflammatory diseases.

  16. LESSONS LEARNED IN DEVELOPMENT OF THE HANFORD SWOC MASTER DOCUMENTED SAFETY ANALYSIS (MDSA) and IMPLEMENTATION VALIDATION REVIEW (IVR)

    International Nuclear Information System (INIS)

    MORENO, M.R.

    2004-01-01

    DOE set clear expectations on a cost-effective approach for achieving compliance with the Nuclear Safety Management requirements (20 CFR 830, Nuclear Safety Rule), which ensured long-term benefit to Hanford, via issuance of a nuclear safety strategy in February 2003. To facilitate implementation of these expectations, tools were developed to streamline and standardize safety analysis and safety document development with the goal of a shorter and more predictable DOE approval cycle. A Hanford Safety Analysis and Risk Assessment Handbook (SARAH) was approved to standardize methodologies for development of safety analyses. A Microsoft Excel spreadsheet (RADIDOSE) was approved for the evaluation of radiological consequences for accident scenarios often postulated at Hanford. Standard safety management program chapters were approved for use as a means of compliance with the programmatic chapters of DOE-STD-3009, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports''. An in-process review was developed between DOE and the Contractor to facilitate DOE approval and provide early course correction. The new Documented Safety Analysis (DSA) developed to address the operations of four facilities within the Solid Waste Operations Complex (SWOC) necessitated development of an Implementation Validation Review (IVR) process. The IVR process encompasses the following objectives: safety basis controls and requirements are adequately incorporated into appropriate facility documents and work instructions, facility personnel are knowledgeable of controls and requirements, and the DSA/TSR controls have been implemented. Based on DOE direction and safety analysis tools, four waste management nuclear facilities were integrated into one safety basis document. With successful completion of implementation of this safety document, lessons-learned from the in-process review, safety analysis tools and IVR process were documented for future action

  17. Seeing The "New Forest": A Visual Curricular Experiment

    Science.gov (United States)

    Garramone, Pariss Nicola

    In contemporary Western contexts, human interaction with and interpretation of nature is a perpetually mediated process. Understandings and engagements with natural environments are informed by and often overlaid with meanings derived from representations. In other words, representations help constitute human relationships with nature. Thus learning how representations shape human understandings and experiences of nature and the resulting social, political, and ecological impact of these mediated relationships has emerged as an important field of inquiry within environmental education. This dissertation examines how a critical, self-reflexive act of looking at photographs can challenge an individual's concepts of nature/culture, real/imaginary, and self/other. The project engages in a curricular experiment where the researcher explores how photography meditates her abstract and embodied understandings of specific natural environments. A critical, self-reflexive approach to aesthetic engagement with photographs moves beyond simply deciphering or decoding representations; it incorporates the learner's own narrative and embodied responses to the photographic representations being explored. This approach also recognizes that pedagogy has a transformative effect; both the learner and the representations being explored are transformed through the process of engagement. In this dissertation, a selection of iconic photographs of Canadian tree planting from the collection of the National Gallery of Canada are looked at: Lorraine Gilbert's (1987-2004) series "Shaping the New Forest" and Sarah Anne Johnson's (2005) work "The Tree Planting Project." The aim of this project is twofold: to unravel how these photographs construct and transform knowledge of and relationships with the environment in Canada, and to demonstrate a model of environmental inquiry that can be integrated into critical environmental education curricula.

  18. “Clubs aren’t like that”: Discos, Deviance and Diegetics in Club Culture Cinema

    Directory of Open Access Journals (Sweden)

    Simon Andrew Morrison

    2012-11-01

    Full Text Available 0 false 18 pt 18 pt 0 0 false false false This article considers ways in which filmmakers have attempted to address the subject of electronic dance music culture on the big screen. In what ways have directors tried to visually represent EDMC in fictional narratives? And to what extent have they been capable of capturing the recognisable elements of this phenomenon, by expressing its tropes and spirit in a plausible and credible fashion? Is it possible to distil the energy of the dance floor and represent the actions, practices and attitudes of its participants for an arguably passive cinema audience? How, for instance, can a key component of this subcultural terrain—drug consumption—be effectively illustrated through the devices of the movie director? By providing textual analysis of two recent, and similarly titled, North American productions—Ecstasy (dir. Lux 2011 and Irvine Welsh’s Ecstasy (dir. Rob Heydon 2012—this account aims to describe, and critique, both the creative approaches and technical devices adopted to solve this artistic problem. With attention to the work of Sarah Thornton, Stan Beeler and Simon Reynolds, this study will also raise questions about authenticity and verisimilitude in an intermediary field in which the dance floor becomes the subject of the non-documentary storyteller and the focus of the camera lens. The article concludes that when a primarily sonic and social medium is re-configured in a visual format, the results, while superficially engaging and entertaining, struggle to capture the charged excitement of the nightclub, the inspirational potency of its soundtrack and, ultimately, the genuine experience of the individual clubgoer.

  19. Experiences of social support among women presenting for obstetric fistula repair surgery in Tanzania

    Directory of Open Access Journals (Sweden)

    Dennis AC

    2016-09-01

    Full Text Available Alexis C Dennis1 Sarah M Wilson1–3 Mary V Mosha4 Gileard G Masenga4 Kathleen J Sikkema1,5,6 Korrine E Terroso1 Melissa H Watt1 1Duke Global Health Institute, Duke University, 2Department of Veterans Affairs, Mid-Atlantic Mental Illness Research, Education and Clinical Center, 3Durham Veterans Affairs Medical Center, Durham, NC, USA; 4Kilimanjaro Christian Medical Center, Moshi, Tanzania; 5Department of Psychology and Neuroscience, Duke University, Durham, NC, USA; 6Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa Objective: An obstetric fistula is a childbirth injury resulting in uncontrollable leakage of urine and/or feces and can lead to physical and psychological challenges, including social isolation. Prior to and after fistula repair surgery, social support can help a woman to reintegrate into her community. The aim of this study was to preliminarily examine the experiences of social support among Tanzanian women presenting with obstetric fistula in the periods immediately preceding obstetric fistula repair surgery and following reintegration.Patients and methods: The study used a mixed-methods design to analyze cross-sectional surveys (n=59 and in-depth interviews (n=20.Results: Women reported widely varying levels of social support from family members and partners, with half of the sample reporting overall high levels of social support. For women experiencing lower levels of support, fistula often exacerbated existing problems in relationships, sometimes directly causing separation or divorce. Many women were assertive and resilient with regard to advocating for their fistula care and relationship needs.Conclusion: Our data suggest that while some women endure negative social experiences following an obstetric fistula and require additional resources and services, many women report high levels of social support from family members and partners, which may be harnessed to improve the holistic

  20. Lasers in tattoo and pigmentation control: role of the PicoSure® laser system

    Directory of Open Access Journals (Sweden)

    Torbeck R

    2016-05-01

    Full Text Available Richard Torbeck,1 Richard Bankowski,2 Sarah Henize,3 Nazanin Saedi,11Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 2Cynosure, Inc, Westford, MA, 3Huron Consulting Group, Chicago, IL, USABackground and objectives: The use of picosecond lasers to remove tattoos has greatly improved due to the long-standing outcomes of nanosecond lasers, both clinically and histologically. The first aesthetic picosecond laser available for this use was the PicoSure® laser system (755/532 nm. Now that a vast amount of research on its use has been conducted, we performed a comprehensive review of the literature to validate the continued application of the PicoSure® laser system for tattoo removal.Study design and methods: A PubMed search was conducted using the term "picosecond" combined with "laser", "dermatology", and "laser tattoo removal".Results: A total of 13 articles were identified, and ten of these met the inclusion criteria for this review. The majority of studies showed that picosecond lasers are an effective and safe treatment mode for the removal of tattoo pigments. Several studies also indicated potential novel applications of picosecond lasers in the removal of various tattoo pigments (eg, black, red, and yellow. Adverse effects were generally mild, such as transient hypopigmentation or blister formation, and were rarely more serious, such as scarring and/or textural change.Conclusion: Advancements in laser technologies and their application in cutaneous medicine have revolutionized the field of laser surgery. Computational modeling provides evidence that the optimal pulse durations for tattoo ink removal are in the picosecond domain. It is recommended that the PicoSure® laser system continue to be used for safe and effective tattoo removal, including for red and yellow pigments.Keywords: tattoo, removal, laser, picosecond 

  1. "No vine para acompañarme, vine para trabajar". O como las mujeres centroamericanas organizan sus hogares transnacionales en Belice City

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    Nanneke Winters

    2009-12-01

    Full Text Available A pesar del creciente interés que ha suscitado el estudio de los procesos de migración internacional desde una perspectiva de género, la mayoría de los estudios solamente describe la migración de hombres y mujeres por separado sin tener en cuenta sus interacciones, o reflexiona sobre la cuestión del empoderamiento de la mujer a través de la migración. Sin embargo, la transformación de familias, hogares y comunidades derivada de la migración es mucho más compleja y requiere de un enfoque relacional más detallado y profundo.En este artículo intento contribuir al estudio de este tema a través del análisis de un componente fundamental de la migración internacional, que es la organización de hogares transnacionales. Con objeto de poder aplicar una perspectiva de género en el análisis de la organización de hogares transnacionales, aplicaré el marco teórico gendered geographies of power desarrollado por Sarah Mahlery Patricia Pessar. El presente estudio está basado en un trabajo de campo sobre las diferentes estrategias que utilizan las mujeres (y hombres centroamericanos que emigran a Belice City para ‘salir adelante’. Sus historias muestran cómo las mujeres migrantes intentan utilizar su condición de mujer transnacional a su favor. A partir de sus experiencias y perspectivas, argumento que el discurso mundial de la migración internacional necesita de un replanteamiento que tomeen cuenta la interacción de hombres y mujeres y las geometrías de poder en que se encuentran los migrantes.

  2. Validity of one-repetition maximum predictive equations in men with spinal cord injury.

    Science.gov (United States)

    Ribeiro Neto, F; Guanais, P; Dornelas, E; Coutinho, A C B; Costa, R R G

    2017-10-01

    Cross-sectional study. The study aimed (a) to test the cross-validation of current one-repetition maximum (1RM) predictive equations in men with spinal cord injury (SCI); (b) to compare the current 1RM predictive equations to a newly developed equation based on the 4- to 12-repetition maximum test (4-12RM). SARAH Rehabilitation Hospital Network, Brasilia, Brazil. Forty-five men aged 28.0 years with SCI between C6 and L2 causing complete motor impairment were enrolled in the study. Volunteers were tested, in a random order, in 1RM test or 4-12RM with 2-3 interval days. Multiple regression analysis was used to generate an equation for predicting 1RM. There were no significant differences between 1RM test and the current predictive equations. ICC values were significant and were classified as excellent for all current predictive equations. The predictive equation of Lombardi presented the best Bland-Altman results (0.5 kg and 12.8 kg for mean difference and interval range around the differences, respectively). The two created equation models for 1RM demonstrated the same and a high adjusted R 2 (0.971, Ppredictive equations are accurate to assess individuals with SCI at the bench press exercise. However, the predictive equation of Lombardi presented the best associated cross-validity results. A specific 1RM prediction equation was also elaborated for individuals with SCI. The created equation should be tested in order to verify whether it presents better accuracy than the current ones.

  3. Managing neonatal bowel obstruction: clinical perspectives

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    Desoky SM

    2018-02-01

    Full Text Available Sarah M Desoky,1 Ranjit I Kylat,2 Unni Udayasankar,1 Dorothy Gilbertson-Dahdal1 1Department of Medical Imaging, University of Arizona College of Medicine, Tucson, AZ, USA; 2Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Arizona College of Medicine, Tucson, AZ, USA Abstract: Neonatal intestinal obstruction is a common surgical emergency and occurs in approximately 1 in 2,000 live births. The causes of obstruction are diverse with varied embryological origins, and some underlying etiologies are not yet well described. Some findings of neonatal bowel obstruction can be detected prenatally on ultrasound imaging. The obstruction is classified as “high” when the level of obstruction is proximal to the ileum, and “low” when the level of obstruction is at the ileum or colon. Early diagnosis of the type of intestinal obstruction and localization of the obstructive bowel segment guides timely and appropriate management of the underlying pathologic entity. Neonatal bowel obstructions are ideally managed at specialized centers with a large volume of neonatal surgery and dedicated pediatric surgical and anesthesia expertise. Although surgical intervention is necessary in most cases, initial management strategies often target underlying metabolic, cardiac, or respiratory abnormalities. Imaging plays a key role in early and accurate diagnosis of the abnormalities. When bowel obstruction is suspected clinically, initial imaging workup usually involves abdominal radiography, which may direct further evaluation with fluoroscopic examination such as upper gastrointestinal (UGI contrast study or contrast enema. This article provides a comprehensive review of clinical and radiological features of common and less common causes of intestinal obstruction in the neonatal age group, including esophageal atresia, enteric duplication cysts, gastric volvulus, congenital microgastria, hypertrophic pyloric stenosis, duodenal atresia

  4. Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants

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    Pomerenke A

    2016-09-01

    Full Text Available Anna Pomerenke,1 Simon R Lea,1 Sarah Herrick,2 Mark A Lindsay,3 Dave Singh1 1Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust, 2Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University of Manchester, Manchester, 3Department of Pharmacy and Pharmacology, University of Bath, Bath, UK Purpose: Viruses are a common cause of exacerbations in chronic obstructive pulmonary disease (COPD. They activate toll-like receptors (TLRs 3, 7, and 8, leading to a pro-inflammatory response. We have characterized the responses of TLR3 and TLR7/8 in lung tissue explants from COPD patients and control smokers.Methods: We prepared lung whole tissue explants (WTEs from patients undergoing surgery for confirmed or suspected lung cancer. In order to mimic the conditions of viral infection, we used poly(I:C for TLR3 stimulation and R848 for TLR7/8 stimulation. These TLR ligands were used alone and in combination. The effects of tumor necrosis factor α (TNFα neutralization and dexamethasone on TLR responses were examined. Inflammatory cytokine release was measured by enzyme-linked immunosorbent assay and gene expression by quantitative real-time polymerase chain reaction.Results: WTEs from COPD patients released higher levels of pro-inflammatory cytokines compared with WTEs from smokers. Activation of multiple TLRs led to a greater than additive release of TNFα and CCL5. TNFα neutralization and dexamethasone treatment decreased cytokine release.Conclusion: This WTE model shows an enhanced response of COPD compared with controls, suggesting an increased response to viral infection. There was amplification of innate immune responses with multiple TLR stimulation. Keywords: COPD, poly(I:C, R848, cytokines, lung explant

  5. Examining Dark Triad traits in relation to mental toughness and physical activity in young adults

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    Sabouri S

    2016-01-01

    Full Text Available Sarah Sabouri,1 Markus Gerber,2 Dena Sadeghi Bahmani,3 Sakari Lemola,4 Peter J Clough,5 Nadeem Kalak,3 Mahin Shamsi,1 Edith Holsboer-Trachsler,3 Serge Brand2,3 1Faculty of Educational Sciences and Psychology, AllamehTabataba’i University, Tehran, Iran; 2Department of Sport, Exercise and Health, Sport Science Section, University of Basel, 3Center for Affective, Stress and Sleep Disorders, Psychiatric Clinics of the University of Basel, 4Faculty of Psychology, University of Basel, Basel, Switzerland; 5Department of Psychology, Manchester Metropolitan University, Manchester, UK Objective: The Dark Triad (DT describes a set of three closely related personality traits: Machiavellianism, narcissism, and psychopathy. Mental toughness (MT refers to a psychological construct combining confidence, commitment, control, and challenge. High MT is related to greater physical activity (PA and, relative to men, women have lower MT scores. The aims of the present study were 1 to investigate the association between DT, MT, and PA, and 2 to compare the DT, MT, and PA scores of men and women.Methods: A total of 341 adults (M=29 years; 51.6% women; range: 18–37 years took part in the study. Participants completed a series of questionnaires assessing DT, MT, and PA.Results: Machiavellianism, narcissism, and psychopathy were all significantly associated with higher MT scores (rs =0.45, 0.50, and 0.20, respectively. DT traits and MT were associated with more vigorous PA. Compared to men, women participants had lower scores for DT traits (overall score and psychopathy, while no differences were found for MT or PA in both sexes.Conclusion: DT traits, high MT, and vigorous PA are interrelated. This pattern of results might explain why, for instance, successful professional athletes can at the same time be tough and ruthless. Keywords: dark triad, mental toughness, physical activity, young adults, sex

  6. Neural correlates of fear: insights from neuroimaging

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    Garfinkel SN

    2014-12-01

    Full Text Available Sarah N Garfinkel,1,2 Hugo D Critchley1,2 1Sackler Centre for Consciousness Science, 2Department of Psychiatry, Brighton and Sussex Medical School, University of Sussex, Brighton, UK Abstract: Fear anticipates a challenge to one's well-being and is a reaction to the risk of harm. The expression of fear in the individual is a constellation of physiological, behavioral, cognitive, and experiential responses. Fear indicates risk and will guide adaptive behavior, yet fear is also fundamental to the symptomatology of most psychiatric disorders. Neuroimaging studies of normal and abnormal fear in humans extend knowledge gained from animal experiments. Neuroimaging permits the empirical evaluation of theory (emotions as response tendencies, mental states, and valence and arousal dimensions, and improves our understanding of the mechanisms of how fear is controlled by both cognitive processes and bodily states. Within the human brain, fear engages a set of regions that include insula and anterior cingulate cortices, the amygdala, and dorsal brain-stem centers, such as periaqueductal gray matter. This same fear matrix is also implicated in attentional orienting, mental planning, interoceptive mapping, bodily feelings, novelty and motivational learning, behavioral prioritization, and the control of autonomic arousal. The stereotyped expression of fear can thus be viewed as a special construction from combinations of these processes. An important motivator for understanding neural fear mechanisms is the debilitating clinical expression of anxiety. Neuroimaging studies of anxiety patients highlight the role of learning and memory in pathological fear. Posttraumatic stress disorder is further distinguished by impairment in cognitive control and contextual memory. These processes ultimately need to be targeted for symptomatic recovery. Neuroscientific knowledge of fear has broader relevance to understanding human and societal behavior. As yet, only some of

  7. Enhancement of encapsulation efficiency of nanoemulsion-containing aripiprazole for the treatment of schizophrenia using mixture experimental design

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    Fard Masoumi HR

    2015-10-01

    Full Text Available Hamid Reza Fard Masoumi, Mahiran Basri, Wan Sarah Samiun, Zahra Izadiyan, Chaw Jiang Lim Nanodelivery Group, Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia Abstract: Aripiprazole is considered as a third-generation antipsychotic drug with excellent therapeutic efficacy in controlling schizophrenia symptoms and was the first atypical anti­psychotic agent to be approved by the US Food and Drug Administration. Formulation of nanoemulsion-containing aripiprazole was carried out using high shear and high pressure homo­genizers. Mixture experimental design was selected to optimize the composition of nanoemulsion. A very small droplet size of emulsion can provide an effective encapsulation for delivery system in the body. The effects of palm kernel oil ester (3–6 wt%, lecithin (2–3 wt%, Tween 80 (0.5–1 wt%, glycerol (1.5–3 wt%, and water (87–93 wt% on the droplet size of aripiprazole nanoemulsions were investigated. The mathematical model showed that the optimum formulation for preparation of aripiprazole nanoemulsion having the desirable criteria was 3.00% of palm kernel oil ester, 2.00% of lecithin, 1.00% of Tween 80, 2.25% of glycerol, and 91.75% of water. Under optimum formulation, the corresponding predicted response value for droplet size was 64.24 nm, which showed an excellent agreement with the actual value (62.23 nm with residual standard error <3.2%. Keywords: schizoaffective disorder, antipsychotic drug, bipolar I disorder, D-optimal mixture design, optimization formulation

  8. Tuberculosis case finding in first-degree relative contacts not living with index tuberculosis cases in Kampala, Uganda

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    Chheng P

    2015-10-01

    Full Text Available Phalkun Chheng,1,2 Mary Nsereko,2 LaShaunda L Malone,2 Brenda Okware,2 Sarah Zalwango,2 Moses Joloba,2,3 W Henry Boom,2 Ezekiel Mupere,1,2,4 Catherine M Stein1,2 On behalf of the Tuberculosis Research Unit 1Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA; 2Uganda-Case Western Reserve University Research Collaboration, 3Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda; 4Department of Pediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda Purpose: To assess the prevalence of pulmonary tuberculosis among first-degree relative (FDR contacts not living with tuberculosis (TB cases. Methods: A cross-sectional analysis of household contacts living with an index TB case and FDR contacts living outside of households in Kampala, Uganda, is presented. Results: A total of 177 contacts (52 FDRs and 125 index household contacts of 31 TB cases were examined. Compared with index household contacts, FDR contacts were older, more likely to be TB symptomatic (50% vs 33%, had a higher percentage of abnormal chest X-rays (19% vs 11%, sputum smear positive (15% vs 5%, and many similar epidemiologic risk factors, including HIV infection (13% vs 10%. Contact groups had similar pulmonary tuberculosis prevalence: 9.6% in FDR vs 10.4% in index household contacts and similar Mycobacterium tuberculosis infection: 62% in FDR vs 61% in index households. Conclusion: TB is common among FDR contacts. High TB prevalence justifies targeting FDRs during household contact investigations. Combining TB active-case finding among FDR contacts with household contact investigation in low-income setting is feasible. This should be part of national TB control program strategies for increasing TB case-detection rates and reducing community TB transmission and death. Keywords: prevalence of pulmonary tuberculosis, limited resource setting, contact tracing

  9. Reduced Order Modeling in General Relativity

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    Tiglio, Manuel

    2014-03-01

    Reduced Order Modeling is an emerging yet fast developing filed in gravitational wave physics. The main goals are to enable fast modeling and parameter estimation of any detected signal, along with rapid matched filtering detecting. I will focus on the first two. Some accomplishments include being able to replace, with essentially no lost of physical accuracy, the original models with surrogate ones (which are not effective ones, that is, they do not simplify the physics but go on a very different track, exploiting the particulars of the waveform family under consideration and state of the art dimensional reduction techniques) which are very fast to evaluate. For example, for EOB models they are at least around 3 orders of magnitude faster than solving the original equations, with physically equivalent results. For numerical simulations the speedup is at least 11 orders of magnitude. For parameter estimation our current numbers are about bringing ~100 days for a single SPA inspiral binary neutron star Bayesian parameter estimation analysis to under a day. More recently, it has been shown that the full precessing problem for, say, 200 cycles, can be represented, through some new ideas, by a remarkably compact set of carefully chosen reduced basis waveforms (~10-100, depending on the accuracy requirements). I will highlight what I personally believe are the challenges to face next in this subarea of GW physics and where efforts should be directed. This talk will summarize work in collaboration with: Harbir Antil (GMU), Jonathan Blackman (Caltech), Priscila Canizares (IoA, Cambridge, UK), Sarah Caudill (UWM), Jonathan Gair (IoA. Cambridge. UK), Scott Field (UMD), Chad R. Galley (Caltech), Frank Herrmann (Germany), Han Hestahven (EPFL, Switzerland), Jason Kaye (Brown, Stanford & Courant). Evan Ochsner (UWM), Ricardo Nochetto (UMD), Vivien Raymond (LIGO, Caltech), Rory Smith (LIGO, Caltech) Bela Ssilagyi (Caltech) and MT (UMD & Caltech).

  10. Advances in the management of cardiovascular risk for patients with type 2 diabetes: perspectives from the Academy for Cardiovascular Risk, Outcomes and Safety Studies in Type 2 Diabetes

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    Schernthaner G

    2017-01-01

    Full Text Available Guntram Schernthaner,1 Sarah Jarvis,2 Chaim Lotan,3 Martin Prázný,4 Christoph Wanner,5 Thomas C Wascher6 1Department of Medicine, Rudolfstiftung Hospital, Vienna, Austria; 2Richford Gate Medical Practice, London, UK; 3Cardiovascular Division, Heart Institute, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; 4First Faculty of Medicine, Charles University, Prague, Czech Republic; 5Department of Medicine, University Hospital, Würzburg, Germany; 6First Medical Department, Hanusch-Krankenhaus, Vienna, Austria Abstract: Diabetes is a global health emergency projected to affect 642 million people by 2040. Type 2 diabetes (T2D represents 90% of diabetes cases and is associated with a range of cardiovascular (CV risk factors that are more than double the incidence of CV disease and significantly increase mortality rates. Diabetes treatments have typically focused on improving glycemic control but their effect on CV outcomes has remained uncertain. In 2008, the US Food and Drug Administration (FDA looked to address this knowledge gap and mandated CV outcome trials (CVOTs for all new antidiabetic therapies. In 2015, EMPA-REG OUTCOME® became the first CVOT to present results for a sodium/glucose cotransporter 2 (SGLT2; also known as SLC5A2 inhibitor, empagliflozin. Subsequently, a regional meeting of the Academy for Cardiovascular Risk, Outcomes and Safety Studies in Type 2 Diabetes (ACROSS T2D brought together a respected faculty of international experts and 150 physicians from 14 countries to discuss the current unmet medical needs of patients with T2D, the results from the EMPA-REG OUTCOME study and the implications of these results for clinical practice. This article summarizes the current scientific evidence and the discussions that took place at the ACROSS T2D regional meeting, which was held in Vienna, Austria, on May 30, 2016. Keywords: type 2 diabetes, cardiovascular risk, SGLT2 inhibitor, CVOTs, empagliflozin

  11. Knowledge and attitudes about emergency contraception among pharmacist and physician preceptors in South Carolina

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    Sarah Shrader

    2010-08-01

    Full Text Available Sarah Shrader1,2, Ann M Rodden1, Lisa Carroll3, Lars E Peterson11Medical University of South Carolina, Department of Family Medicine, Charleston, SC, USA; 2South Carolina College of Pharmacy, Department of Clinical Pharmacy and Outcomes Sciences, Charleston, SC, USA; 3Spartanburg Regional Family Medicine Residency Program, Department of Family Medicine, Spartanburg, SC, USABackground: Emergency contraception (EC may reduce unintended pregnancies if patients are informed and have access. A great deal of medical education occurs during medical and pharmacy training community clerkships. This study concurrently assesses knowledge and attitudes about EC between community physician and pharmacist preceptors who prescribe/dispense EC.Study design: Electronic survey of demographic information, knowledge-based, and attitude questions related to EC was completed by 182 (36.6% response rate South Carolina ­community physicians and pharmacists who precept students. Comparisons were performed using chi-square or Fischer’s exact test.Results: In the study population, approximately 62% of pharmacists dispense EC while only 28% of physicians prescribe it. More physicians than pharmacists believe repetitive use is not harmful (48.3% vs 28.0%, P = 0.010, while more pharmacists believe it causes birth defects (22.6% vs 7.9%, P = 0.008.Conclusion: Overall, both physicians and pharmacists have poor knowledge about EC. ­Further education for both groups may be needed so future physicians and pharmacists are not taught incorrectly during their training and so patient access is not hampered by prescriber misunderstanding.Keywords: emergency contraception, levonorgestrel, pharmacist, physician

  12. Modelling soil sodium and potassium adsorption ratio (SPAR) in the immediate period after a grassland fire in Lithuania.

    Science.gov (United States)

    Pereira, Paulo; Cerda, Artemi; Misiūnė, Ieva

    2015-04-01

    The soil sodium and potassium adsorption ratio (SPAR) is an index that measures the amount of sodium and potassium adsorbed onto clay and organic matter surfaces, in relation to calcium and magnesium. Assess the potential of soil dispersion or flocculation, a process which has implication in soil hydraulic properties and erosion (Sarah, 2004). Depending on severity and the type of ash produced, fire can changes in the immediate period the soil nutrient status (Bodi et al. 2014). Ash releases onto soil surface a large amount of cations, due the high pH. Previous works showed that SPAR from ash slurries is higher than solutions produced from litter (Pereira et al., 2014a). Normally the spatial distribution of topsoil nutrients in the immediate period after the fire is very heterogeneous, due to the different impacts of fire. Thus it is important to identify the most accurate interpolation method in order to identify with better precision the impacts of fire on soil properties. The objective of this work is to test several interpolation methods. The study area is located in near Vilnius (Lithuania) at 54° 42' N, 25° 08 E, 158 masl. Four days after the fire it was designed a plot in a burned area with near Vilnius (Lithuania) at 54° 42' N, 25° 08 E, 158 masl. Twenty five samples were collected from the topsoil. The SPAR index was calculated according to the formula: (Na++K+)/(Ca2++Mg2+)1/2 (Sarah, 2004). Data followed the normal distribution, thus no transformation was required previous to data modelling. Several well know interpolation models were tested, as Inverse Distance to a Weight (IDW) with the power of 1, 2, 3 and 4, Radial Basis Functions (RBF), Inverse Multiquadratic (IMT), Multilog (MTG), Multiquadratic (MTQ), Natural Cubic Spline (NCS) and Thin Plate Spline (TPS) and Local Polynomial (LP) with the power of 1 and 2 and Ordinary Kriging. The best interpolator was the one which had the lowest Root Mean Square Error (RMSE) (Pereira et al., 2014b). The

  13. Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

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    Ong YS

    2016-11-01

    Full Text Available Yong Sze Ong,1 Latifah Saiful Yazan,1,2 Wei Keat Ng,1 Mustapha M Noordin,3 Sarah Sapuan,1 Jhi Biau Foo,1 Yin Sim Tor1 1Laboratory of Molecular Biomedicine, Institute of Bioscience, 2Department of Biomedical Science, Faculty of Medicine and Health Sciences, 3Department of Pathology and Veterinary Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia Background: Thymoquinone (TQ, the predominant active lipophilic component in Nigella sativa seed oil, has a variety of pharmacological properties such as anticancer activities. However, translation of TQ to clinical phase is still not possible due to its hydrophobic properties. This problem can be solved by encapsulating it in nanoformulations to enhance its pharmacological properties. In our previous study, TQ has been successfully encapsulated in a nanostructured lipid carrier (hereinafter referred to as TQNLC with excellent physiochemical properties such as high encapsulation efficiency, high drug-loading capacity, particle diameter less than 100 nm, and stability up to 2 years. In vitro studies also proved that TQNLC exhibited antiproliferative activity toward breast and cervical cancer cell lines. However, no toxicity profile related to this formulation has been reported. In this study, we determine and compare the in vivo toxicity of both TQNLC and TQ. Materials and methods: The in vivo toxicity (acute and subacute toxicity study was carried out by oral administration of TQNLC and TQ to BALB/c mice. Animal survival, body weight, organ weight-to-body weight ratio, hematological profile, biochemistry profile, and histopathological changes were analyzed. Results: In acute toxicity, TQ that is loaded in nanostructured lipid carrier (NLC was found to be less toxic than pure TQ. It can be concluded that encapsulation of TQ in lipid carrier minimizes the toxicity of the compound. In the subacute toxicity study, oral administration of 100 mg/kg of TQNLC and TQ

  14. Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of eating disorders.

    Science.gov (United States)

    Hay, Phillipa; Chinn, David; Forbes, David; Madden, Sloane; Newton, Richard; Sugenor, Lois; Touyz, Stephen; Ward, Warren

    2014-11-01

    guide practice. Specific evidence based psychological and pharmacological treatments are recommended for most eating disorders but more trials are needed for specific therapies in AN, and research is urgently needed for all aspects of ARFID assessment and management. Associate Professor Susan Byrne, Dr Angelica Claudino, Dr Anthea Fursland, Associate Professor Jennifer Gaudiani, Dr Susan Hart, Ms Gabriella Heruc, Associate Professor Michael Kohn, Dr Rick Kausman, Dr Sarah Maguire, Ms Peta Marks, Professor Janet Treasure and Mr Andrew Wallis. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  15. From enzymes and viruses to clouds, snow, sea-glaciers, and green icebergs: How a protein crystallographer got into glaciology and atmospheric radiation

    Science.gov (United States)

    Warren, S. G.

    2016-12-01

    Through a series of lucky breaks beginning five years after my Ph.D., I was able to change careers from molecular biology to earth science, via a postdoc at NCAR in 1978, leading to a job at the University of Washington (UW) in 1982. Steve Schneider, Warren Wiscombe, Julius London, Gary Thomas, and Ed LaChapelle helped me make the transition. At UW, a collaboration with Tom Grenfell got me started in Antarctic fieldwork. Long-term dedicated coworkers Carole Hahn (cloud climatology) and Rich Brandt (radiative and thermal properties of snow and sea ice) kept our funded projects going. Conversations with UW colleagues Bob Charlson on dimethyl sulfide (DMS) and Qiang Fu on the microwave sounding unit (MSU) enticed me into unfunded projects (biological influence on cloud albedo; satellite-derived tropospheric temperatures). Several other key collaborators I first met when they were students at UW: Tony Clarke and Sarah Doherty (black carbon in snow), Bonnie Light (laboratory experiments for Snowball Earth), and Von Walden (longwave radiation spectra). Ian Allison of the Australian Antarctic Division sponsored my first sabbatical, to learn about sea ice. Most of our work, of course, is on projects that are proposed, then funded, then completed (or not completed). But at least as much fun are projects that were completed but not proposed. Some of these were inspired by listening to seminars (particularly by Charlson), or were developed from student term-papers in my snow-and-ice class (Jon Rhodes's report on suncups, and Steve Hudson's on Antarctic bacteria). There is not much cross-cultural connection between my former life and my current life, but there is some, now institutionalized in UW's Astrobiology Program. My enthusiasm for the CLAW project was partly motivated by my background in biology and the knowledge that DMS originates from the amino acid methionine. I was happy to accept oceanic biota as the explanation for the color of green icebergs. And my motivation

  16. Alterations in cancer cell mechanical properties after fluid shear stress exposure: a micropipette aspiration study

    Directory of Open Access Journals (Sweden)

    Chivukula VK

    2015-01-01

    Full Text Available Venkat Keshav Chivukula,1 Benjamin L Krog,1,2 Jones T Nauseef,2 Michael D Henry,2 Sarah C Vigmostad1 1Department of Biomedical Engineering, 2Department of Molecular Physiology and Biophysics, Holden Comprehensive Cancer Center, University of Iowa, Seamans Center for the Engineering Arts and Sciences, Iowa City, IA, USA Abstract: Over 90% of cancer deaths result not from primary tumor development, but from metastatic tumors that arise after cancer cells circulate to distal sites via the circulatory system. While it is known that metastasis is an inefficient process, the effect of hemodynamic parameters such as fluid shear stress (FSS on the viability and efficacy of metastasis is not well understood. Recent work has shown that select cancer cells may be able to survive and possibly even adapt to FSS in vitro. The current research seeks to characterize the effect of FSS on the mechanical properties of suspended cancer cells in vitro. Nontransformed prostate epithelial cells (PrEC LH and transformed prostate cancer cells (PC-3 were used in this study. The Young's modulus was determined using micropipette aspiration. We examined cells in suspension but not exposed to FSS (unsheared and immediately after exposure to high (6,400 dyn/cm2 and low (510 dyn/cm2 FSS. The PrEC LH cells were ~140% stiffer than the PC-3 cells not exposed to FSS. Post-FSS exposure, there was an increase of ~77% in Young's modulus after exposure to high FSS and a ~47% increase in Young's modulus after exposure to low FSS for the PC-3 cells. There was no significant change in the Young's modulus of PrEC LH cells post-FSS exposure. Our findings indicate that cancer cells adapt to FSS, with an increased Young's modulus being one of the adaptive responses, and that this adaptation is specific only to PC-3 cells and is not seen in PrEC LH cells. Moreover, this adaptation appears to be graded in response to the magnitude of FSS experienced by the cancer cells. This is the first study

  17. Health care resource utilization before and after natalizumab initiation among patients with multiple sclerosis in Germany

    Directory of Open Access Journals (Sweden)

    Watson C

    2017-02-01

    Full Text Available Crystal Watson,1 Christine Prosser,2 Sebastian Braun,2 Pamela B Landsman-Blumberg,3 Erika Gleissner,4 Sarah Naoshy1 1Health Economics and Outcomes Research, Global Market Access, Biogen, Cambridge, MA, USA; 2Real World Evidence, Xcenda GmbH, Hanover, Germany; 3Applied Data Analytics, Xcenda LLC, Palm Harbor, FL, USA; 4Market Access, Biogen, Ismaning, Germany Background: Multiple sclerosis (MS, a progressive neurodegenerative disease, greatly impacts the quality of life and economic status of people affected by this disease. In Germany, the total annual cost of MS is estimated at €40,000 per person with MS. Natalizumab has shown to slow MS disease progression, reduce relapses, and improve the quality of life of people with MS.Objective: To evaluate MS-related and all-cause health care resource utilization and costs among German MS patients during the 12 months before and after initiation of natalizumab in a real-world setting.Methods: The current analysis was conducted using the Health Risk Institute research database. Identified patients were aged ≥18 years with ≥1 diagnosis of MS and had initiated natalizumab therapy (index, with 12-month pre– and post–index-period data. Patients were stratified by prior disease-modifying therapy (DMT usage or no DMT usage in the pre-index period. Outcome measures included corticosteroid use and number of sick/disability days, inpatient stays, and outpatient visits. Health care costs were calculated separately for pre- and post-index periods on a per-patient basis and adjusted for inflation.Results: In a final sample of 193 natalizumab-treated patients, per-patient MS-related corticosteroid use was reduced by 62.3%, MS-related sick days by 27.6%, and inpatient costs by 78.3% from the pre- to post-index period. Furthermore, the proportion of patients with MS-related hospitalizations decreased from 49.7% to 14.0% (P<0.001; this reduction was seen for patients with and without prior DMT use

  18. Beta-blocker under-use in COPD patients

    Directory of Open Access Journals (Sweden)

    Lim KP

    2017-10-01

    Full Text Available Kuan Pin Lim,1,2 Sarah Loughrey,1 Michael Musk,1,2 Melanie Lavender,1,2 Jeremy P Wrobel1–3 1Advanced Lung Disease Unit, Royal Perth Hospital, Perth, WA, Australia; 2Respiratory Department, Fiona Stanley Hospital, Murdoch, WA, Australia; 3School of Medicine, University of Notre Dame, Fremantle, WA, Australia Background: Cardiovascular (CVS comorbidities are common in COPD and contribute significantly to morbidity and mortality, especially following acute exacerbations of COPD (AECOPD. Beta-blockers (BBs are safe and effective in COPD patients, with demonstrated survival benefit following myocardial infarction. We sought to determine if BBs are under-prescribed in patients hospitalized with AECOPD. We also sought to determine inpatient rates of CVS and cerebrovascular complications, and their impact on patient outcomes. Methods: Retrospective hospital data was collected over a 12-month period. The medical records of all patients >40 years of age coded with a diagnosis of AECOPD were analyzed. Prevalent use and incident initiation of BBs were assessed. Comorbidities including indications and contraindications for BB use were analyzed. Results: Of the 366 eligible patients, 156 patients (42.6% had at least one indication for BB use – of these patients, only 53 (34.0% were on BB therapy and 61 (39.1% were not on BB therapy but had no listed contraindication. Prevalent use of BBs at the time of admission in all 366 patients was 19.7%, compared with 45.6%, 39.6% and 45.9% use of anti-platelets, statins and angiotensin-converting enzyme inhibitor/angiotensin II receptor blockers, respectively. CVS and cerebrovascular complications were common in this population (57 patients, 16% and were associated with longer length of stay (p<0.01 and greater inpatient mortality (p=0.02. Conclusions: BBs are under-prescribed in COPD patients despite clear indication(s for their use. Further work is required to explore barriers to BB prescribing in COPD patients

  19. Relationship between lung function and grip strength in older hospitalized patients: a pilot study

    Directory of Open Access Journals (Sweden)

    Holmes SJ

    2017-04-01

    Full Text Available Sarah J Holmes,1 Stephen C Allen,2,3 Helen C Roberts4,5 1Medicine and Elderly Care, Hampshire Hospitals NHS Foundation Trust, Winchester, 2Medicine and Geriatrics, The Royal Bournemouth Hospital and Christchurch Hospitals NHS Foundation Trust, Bournemouth, 3Centre of Postgraduate Medical Research and Education, Bournemouth University, Poole, 4Academic Geriatric Medicine, University of Southampton, 5University Hospital Southampton NHS Foundation Trust, Southampton, UK Objective: Older people with reduced respiratory muscle strength may be misclassified as having COPD on the basis of spirometric results. We aimed to evaluate the relationship between lung function and grip strength in older hospitalized patients without known airways disease.Methods: Patients in acute medical wards were recruited who were aged ≥70 years; no history, symptoms, or signs of respiratory disease; Mini Mental State Examination ≥24; willing and able to consent to participate; and able to perform hand grip and forced spirometry. Data including lung function (forced expiratory volume in 1 second [FEV1], forced vital capacity [FVC], FEV1/FVC, peak expiratory flow rate [PEFR], and slow vital capacity [SVC], grip strength, age, weight, and height were recorded. Data were analyzed using descriptive statistics and linear regression unadjusted and adjusted (for age, height, and weight.Results: A total of 50 patients (20 men were recruited. Stronger grip strength in men was significantly associated with greater FEV1, but this was attenuated by adjustment for age, height, and weight. Significant positive associations were found in women between grip strength and both PEFR and SVC, both of which remained robust to adjustment.Conclusion: The association between grip strength and PEFR and SVC may reflect stronger patients generating higher intrathoracic pressure at the start of spirometry and pushing harder against thoracic cage recoil at end-expiration. Conversely, patients with

  20. Training driving ability in a traumatic brain-injured individual using a driving simulator: a case report

    Directory of Open Access Journals (Sweden)

    Imhoff S

    2017-02-01

    Full Text Available Sarah Imhoff,1,2 Martin Lavallière,3,4 Mathieu Germain-Robitaille,5 Normand Teasdale,5–7 Philippe Fait,1,2,8 1Department of Human Kinetics, 2Research Group on Neuromusculoskeletal Dysfunctions (GRAN, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada; 3Massachusetts Institute of Technology AgeLab, Cambridge, MA, USA; 4Department of Health Sciences, Program of Kinesiology, Université du Québec à Chicoutimi, Chicoutimi, 5Faculté de Médecine, Département de Kinésiologie, 6Groupe de recherche en analyse du mouvement et ergonomie, Université Laval, 7CHU de Québec – Université Laval, Centre d’excellence sur le vieillissement de Québec, 8Research Center in Neuropsychology and Cognition (CERNEC, Montréal, QC, Canada Background: Traumatic brain injury (TBI causes functional deficits that may significantly interfere with numerous activities of daily living such as driving. We report the case of a 20-year-old woman having lost her driver’s license after sustaining a moderate TBI.Objective: We aimed to evaluate the effectiveness of an in-simulator training program with automated feedback on driving performance in a TBI individual.Methods: The participant underwent an initial and a final in-simulator driving assessment and 11 in-simulator training sessions with driving-specific automated feedbacks. Driving performance (simulation duration, speed regulation and lateral positioning was measured in the driving simulator.Results: Speeding duration decreased during training sessions from 1.50 ± 0.80 min (4.16 ± 2.22% to 0.45 ± 0.15 min (0.44 ± 0.42% but returned to initial duration after removal of feedbacks for the final assessment. Proper lateral positioning improved with training and was maintained at the final assessment. Time spent in an incorrect lateral position decreased from 18.85 min (53.61% in the initial assessment to 1.51 min (4.64% on the final assessment.Conclusion: Driving simulators represent an