WorldWideScience

Sample records for hud caller id

  1. 76 FR 16367 - Implementation of the Truth in Caller ID Act of 2009

    Science.gov (United States)

    2011-03-23

    ...IP service,'' and defining ``Caller identification service'' to mean ``any service or device designed... identification information in technologies that are successor or replacement technologies to telecommunications... from causing any caller identification service to knowingly transmit misleading or inaccurate caller ID...

  2. 78 FR 77024 - Telemarketing Sales Rule; Notice of Termination of Caller ID Rulemaking

    Science.gov (United States)

    2013-12-20

    ...' Caller ID displays, subjecting them to consumer complaints and the loss of business goodwill.\\16\\ \\14\\ E...., Herb Weisbaum, Why aren't phone companies doing more to block robocalls?, NBC News, July 17, 2013, www.nbcnews.com/business/why-arent-phone-companies-doing-more-block-robocalls-6C10641251 ; www.nomorobo.com...

  3. Caller I.D. and ANI: The Technology and the Controversy.

    Science.gov (United States)

    Bertot, John C.

    1992-01-01

    Examines telephone caller identification (caller-I.D.) and Automatic Number Identification (ANI) technology and discusses policy and privacy issues at the state and federal levels of government. A comparative analysis of state caller-I.D. adoption policies is presented, caller-I.D. blocking is discussed, costs are reported, and legal aspects of…

  4. HUD Homeownership Centers

    Data.gov (United States)

    Department of Housing and Urban Development — HUD Homeownership Centers (HOCs) insure single family Federal Housing Administration (FHA) mortgages and oversee the selling of HUD homes. FHA has four Homeownership...

  5. HUD Exchange Grantee Database

    Data.gov (United States)

    Department of Housing and Urban Development — The About Grantees section of the HUD Exchange brings up contact information, reports, award, jurisdiction, and location data for organizations that receive HUD...

  6. Mystery callers: het zijn net mensen

    NARCIS (Netherlands)

    Ammeraal, Annette N.; Hoekstra, Janita; van Hijum, Arjen; Leeflang, Pieter; Bronner, Fred; Dekker, Paul; de Leeuw, Edith; Paas, Leo; de Ruyter, Ko; Smidts, Ale; Wieringa, Jaap

    2014-01-01

    Mystery calling is a specific form of mystery guest-research. With this type of marketing research one can evaluate telephone contacts with customers. In this contribution we evaluate how mystery callers judge the service quality of a customer contact centre of a service organisation. We compare the

  7. Mystery callers: het zijn net mensen

    NARCIS (Netherlands)

    Ammeraal, Annette N.; Hoekstra, Janita; van Hijum, Arjen; Leeflang, Pieter; Bronner, Fred; Dekker, Paul; de Leeuw, Edith; Paas, Leo; de Ruyter, Ko; Smidts, Ale; Wieringa, Jaap

    2014-01-01

    Mystery calling is a specific form of mystery guest-research. With this type of marketing research one can evaluate telephone contacts with customers. In this contribution we evaluate how mystery callers judge the service quality of a customer contact centre of a service organisation. We compare the

  8. HUD GIS Boundary Files

    Data.gov (United States)

    Department of Housing and Urban Development — The HUD GIS Boundary Files are intended to supplement boundary files available from the U.S. Census Bureau. The files are for community planners interested in...

  9. HUD TRM Report

    Data.gov (United States)

    Department of Housing and Urban Development — HUD uses certain systems and software to conduct daily business. It is important for our project managers and contractors to know the different platforms and...

  10. HUD's Local Office Directory

    Data.gov (United States)

    Department of Housing and Urban Development — HUD is organized in 10 Regions. Each Region is managed by a Regional Administrator, who also oversees the Regional Office. Each Field Office within a Region is...

  11. Empirical Investigation of Word Callers Who Are English Learners

    Science.gov (United States)

    Knight-Teague, Kerri; Vanderwood, Michael L.; Knight, Erin

    2014-01-01

    Oral reading fluency is frequently used in school settings to assess student reading skills, but it is somewhat commonly believed that some students can read words fluently while not comprehending (i.e., word callers). Previous studies examining the prevalence of word callers typically included native English speakers rather than English learners…

  12. 24 CFR Appendix A to Part 3500 - Instructions for Completing HUD-1 and HUD-1a Settlement Statements; Sample HUD-1 and HUD-1a...

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Instructions for Completing HUD-1 and HUD-1a Settlement Statements; Sample HUD-1 and HUD-1a Statements A Appendix A to Part 3500 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE...

  13. Triage and patient satisfaction among callers in Swedish computer-supported telephone advice nursing.

    Science.gov (United States)

    Rahmqvist, Mikael; Ernesäter, Annica; Holmström, Inger

    2011-01-01

    We investigated satisfaction with a Swedish telenursing service and the health-care-seeking behaviour among callers who received a less urgent level of health care than they expected. A postal questionnaire was sent to a random selection of callers (n = 273) to Swedish Healthcare Direct in October 2008. The 'cases' were 18 callers where the telenurse recommended a lower level of health care than the caller expected and who were not in complete agreement with the nurse. The 'controls' were 22 callers who either received a lower recommendation, or were in disagreement with the recommendation. There were no differences between cases, controls and other callers regarding background factors or the telenurse classification of emergency. However, both cases and controls considered their need for health care as more urgent than the other callers. An independent test of the nurses' reception, ability to listen and to take notice of the callers' health problem, showed that nurses who had served cases, had received a significantly lower rating than other nurses. For nurses who had served controls, there was no such difference in rating. Cases and controls had fewer subsequent care visits than other callers, in the three days following the call, although the proportion of emergency visits was higher among cases and controls compared to other callers. If the caller and the nurse disagree about the nurse's recommendations, the consequence can be a dissatisfied caller and more visits to unnecessary high levels of health care. Further training of the nurses may improve the telenurse service.

  14. Crisis Intervener Perceptions of the Stressfulness of Caller Problems.

    Science.gov (United States)

    McCarthy, Patricia R.; Reese, Robin G.

    The importance of volunteers in the provision of mental health crisis intervention services has been well documented. However, the volunteer turn-over rate is quite high, due to factors such as burnout. This study examined stressfulness in relationship to caller problems, as well as variables related to perceptions of stress. In this study…

  15. HUD Digital Government Strategy Report

    Data.gov (United States)

    Department of Housing and Urban Development — The HUD Digital Strategic Plan clearly articulates the goals of openness and transparency, furthering the innovation economy and meeting more global government wide...

  16. HUD Approved Housing Counseling Agencies

    Data.gov (United States)

    Department of Housing and Urban Development — HUD sponsors housing counseling agencies throughout the country that can provide advice on buying a home, renting, defaults, foreclosures, and credit issues. This...

  17. 76 FR 43196 - Implementation of the Truth in Caller ID Act

    Science.gov (United States)

    2011-07-20

    ... called party. Third, the customer enters the phone number he or she wants to call; and fourth, the... ``interconnected VoIP services,'' we do not need to specify in the rule that the prohibition encompasses calls made... providers to notify their customers in no uncertain terms that such actions are illegal. B. Exemptions...

  18. HUD Subprime and Manufactured Home Lender List

    Data.gov (United States)

    Department of Housing and Urban Development — The U.S. Department of Housing and Urban Development (HUD) periodically produce its HUD Subprime and Manufactured home Lender List for the lenders who specialize in...

  19. 24 CFR 3500.8 - Use of HUD-1 or HUD-1A settlement statements.

    Science.gov (United States)

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT REAL ESTATE SETTLEMENT PROCEDURES ACT § 3500.8 Use of HUD-1 or HUD-1A... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Use of HUD-1 or HUD-1A settlement statements. 3500.8 Section 3500.8 Housing and Urban Development Regulations Relating to Housing and...

  20. Characteristics of Telephone Crisis Hotline Callers with Suicidal Ideation in Japan.

    Science.gov (United States)

    Ohtaki, Yuh; Oi, Yuichi; Doki, Shotaro; Kaneko, Hidetoshi; Usami, Kazuya; Sasahara, Shinichiro; Matsuzaki, Ichiyo

    2017-02-01

    Hotline callers do not always have suicidal ideation and previous studies have noted that the rate of such callers is limited. Crisis hotline counselors must be able to identify high-risk callers in order to provide appropriate support. This study investigated the characteristics of Japanese crisis hotline callers in 2012 (N = 541,694) and is the first to analyze crisis hotline data for all parts of Japan over 1 year. About 14% of the callers had suicidal ideation and 6% had a history of attempted suicide. The odds ratio for suicidal ideation among those with a history of attempted suicide was 15.5. The suicidal ideation rate was much smaller compared to previous studies in other countries. There is a psychological barrier that must be broken for high-risk people to use support hotlines. In addition, attempted suicide is a strong exclusive predisposing factor for death due to suicide; therefore, counselors should pay careful attention to callers with a history of attempted suicide. The characteristics of Japanese crisis hotline callers and the features of suicidal ideation revealed in the present study are expected to be useful in developing telephone crisis hotline strategies.

  1. 24 CFR 891.450 - HUD review.

    Science.gov (United States)

    2010-04-01

    ...) SUPPORTIVE HOUSING FOR THE ELDERLY AND PERSONS WITH DISABILITIES Project Management § 891.450 HUD review. HUD shall conduct periodic on-site management reviews of the Owner's compliance with the requirements of... Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF...

  2. 77 FR 73523 - HUD Acquisition Regulations (HUDAR)

    Science.gov (United States)

    2012-12-10

    ... address the organizational structure of HUD, and adding provisions on contractor record retention. DATES...--Organizational and Consultant Conflicts of Interest 0 22. Revise section 2409.503 to read as follows: 2409.503...

  3. HUD Low and Moderate Income Areas

    Data.gov (United States)

    Department of Housing and Urban Development — This dataset and map service provides information on the U.S. Housing and Urban Development's (HUD) low to moderate income areas. The term Low to Moderate Income,...

  4. HUD Hearings and Appeals Office Decisions

    Data.gov (United States)

    Department of Housing and Urban Development — These all of the Administrative Sanction decisions issued by the Office of Appeals and its predecessor, the HUD Board of Contract Appeals. This Office has included...

  5. HUD Continuum of Care (CoC) Awards (2005-2016)

    Data.gov (United States)

    City and County of Durham, North Carolina — HUD grantees receive funding from HUD to support HUD's mission to create strong, sustainable, inclusive communities and quality affordable homes for all. HUD...

  6. Evaluation of Nine Somatic Variant Callers for Detection of Somatic Mutations in Exome and Targeted Deep Sequencing Data

    DEFF Research Database (Denmark)

    Krøigård, Anne Bruun; Thomassen, Mads; Lænkholm, Anne Vibeke;

    2016-01-01

    a comprehensive evaluation using exome sequencing and targeted deep sequencing data of paired tumor-normal samples from five breast cancer patients to evaluate the performance of nine publicly available somatic variant callers: EBCall, Mutect, Seurat, Shimmer, Indelocator, Somatic Sniper, Strelka, VarScan 2...... and Virmid for the detection of single nucleotide mutations and small deletions and insertions. We report a large variation in the number of calls from the nine somatic variant callers on the same sequencing data and highly variable agreement. Sequencing depth had markedly diverse impact on individual...... callers, as for some callers, increased sequencing depth highly improved sensitivity. For SNV calling, we report EBCall, Mutect, Virmid and Strelka to be the most reliable somatic variant callers for both exome sequencing and targeted deep sequencing. For indel calling, EBCall is superior due to high...

  7. Evaluation of Nine Somatic Variant Callers for Detection of Somatic Mutations in Exome and Targeted Deep Sequencing Data

    DEFF Research Database (Denmark)

    Krøigård, Anne Bruun; Thomassen, Mads; Lænkholm, Anne Vibeke;

    2016-01-01

    Next generation sequencing is extensively applied to catalogue somatic mutations in cancer, in research settings and increasingly in clinical settings for molecular diagnostics, guiding therapy decisions. Somatic variant callers perform paired comparisons of sequencing data from cancer tissue...... a comprehensive evaluation using exome sequencing and targeted deep sequencing data of paired tumor-normal samples from five breast cancer patients to evaluate the performance of nine publicly available somatic variant callers: EBCall, Mutect, Seurat, Shimmer, Indelocator, Somatic Sniper, Strelka, VarScan 2...... callers, as for some callers, increased sequencing depth highly improved sensitivity. For SNV calling, we report EBCall, Mutect, Virmid and Strelka to be the most reliable somatic variant callers for both exome sequencing and targeted deep sequencing. For indel calling, EBCall is superior due to high...

  8. 24 CFR 401.201 - How does HUD select PAEs?

    Science.gov (United States)

    2010-04-01

    ... (MARK-TO-MARKET) Participating Administrative Entity (PAE) and Portfolio Restructuring Agreement (PRA) § 401.201 How does HUD select PAEs? (a) Selection of PAE. HUD will select qualified PAEs in accordance... responsibility for projects in the jurisdiction. If the agencies are unable to agree, HUD will choose a PAE...

  9. 77 FR 9682 - Announcement of Funding Awards for the HUD-Veterans Affairs Supportive Housing (HUD-VASH) Program...

    Science.gov (United States)

    2012-02-17

    ... of Jackson. Housing Authority of Billings 2415 1st Avenue N.... Billings........ MT 59101 111,938 25... factors as specified by HUD in consultation with the VA. On May 6, 2008 (73 FR 25026), HUD published in... have partnered with local VA medical centers. On May 19, 2008 (73 FR 28863), HUD corrected the May...

  10. Evaluation of the Dutch AIDS Information Helpline: An investigation of information needs and satisfaction of callers

    NARCIS (Netherlands)

    A.E.R. Bos (Arjan); G.C. Visser (Gerard); B.F. Tempert; H.P. Schaalma (Herman)

    2004-01-01

    textabstractAIDS telephone hotlines may have an important function in AIDS education, HIV prevention and counseling. In this study, consults of the Dutch AIDS Information Helpline were evaluated to determine the AIDS information needs of the callers and callers’ satisfaction with the telephone-deliv

  11. Norovirus surveillance among callers to foodborne illness complaint hotline, Minnesota, USA, 2011-2013.

    Science.gov (United States)

    Saupe, Amy A; Kaehler, Dawn; Cebelinski, Elizabeth A; Nefzger, Brian; Hall, Aron J; Smith, Kirk E

    2013-08-01

    Norovirus is the leading cause of foodborne disease in the United States. During October 2011-January 2013, we conducted surveillance for norovirus infection in Minnesota among callers to a complaint-based foodborne illness hotline who reported diarrhea or vomiting. Of 241 complainants tested, 127 (52.7%) were positive for norovirus.

  12. Efficacy of Brief Telephone Psychotherapy with Callers to a Suicide Hotline

    Science.gov (United States)

    Rhee, Wayne K.; Merbaum, Michael; Strube, Michael J.; Self, Susan M.

    2005-01-01

    The efficacy of two types of therapy conducted exclusively over the telephone was studied. Clients (N = 55) were recruited from a pool of callers to a suicide hotline and were randomly assigned to a waiting list control (WC) or Solution Focused Brief Therapy (SFBT) or Common Factors Therapy (CFT). It was hypothesized that improvements would be…

  13. Day/night ANVIS/HUD-24 (day HUD) flight test and pilot evaluations

    Science.gov (United States)

    Yona, Zvi; Weiser, Ben; Hamburger, Oded

    2004-09-01

    The Day/Night ANVIS/HUD-24 gives pilots the ultimate head-out flight solution: 24-hour operational capability from a single integrated system. The basic integrated system combines the standard Night Vision Goggle (NVG) image with vital aircraft flight and navigation information, currently operational on over 4500 helicopters worldwide. Introducing the new Day HUD add-on module the same flight information is displayed for day use. The Day Head Up Display (HUD) is an add-on, complimentary to the basic night ANVIS/HUD system (AN/AVS-7). A lightweight optical module enhancing the day flight operation is designed to allow utility and reconnaissance helicopter day-mission operation by providing complete daytime head-out flight information. This add-on unit enhances flight safety, maximizes tactical survivability, and increases situational awareness during critical landing and takeoff phases. The Day HUD offers a unique 25° field-of-view, monocular, see-through flight information display. It mounts directly to the standard NVG mounting, incorporating a state of the art AMLCD flat panel display, high brightness solid-state backlight and compact optics resulting in a high contrast, high visibility display. The Day HUD test and evaluation program included extensive man-machine interface tests and numerous flight test aircraft in more than six separate countries. This paper will also address flight training, customer acceptance and expand on these findings and observations.

  14. IMPACT ASSESSMENT OF TROPICAL CYCLONE HUD HUD ON COASTAL REGION OF VISAKHAPATNAM, ANDHRA PRADESH, INDIA

    Directory of Open Access Journals (Sweden)

    G. Vivek

    2015-10-01

    Full Text Available Tropical cyclone is a rapidly rotating storm system characterized by a low pressure center, strong winds, and a spiral arrangements of thunderstorms that produce heavy rain. Tropical cyclones typically form over large bodies of relatively warm water. On 6th October 2014 Hud Hud originates from a low pressure system that formed under the influence of an upper air cyclonic circulation in the Andaman Sea. On 9th October 2014 the IMD department classified the Hud Hud as a very severe cyclonic storm on IMD scale and category 4 on Staffir-Simpson scale. The cyclone hit the coast of Visakhapatnam on 12th October 2014 at wind speed of 175 km/h which caused extensive damage to the city and the neighbouring districts. The damage caused by Cyclone Hud Hud not only changed the landscape of the port city, but also made it the first city in the country to be directly hit by a cyclone since 1891 as per the records of the IMD. The remote sensing technique used here is NDVI. NDVI will separate vegetation and non-vegetation part. The NDVI will be classified in ERDAS and calculated the area using ARCGIS. The satellite data of 4th October 2014 show s before the cyclone, 14th October 2014 shows after the cyclone and 7th December 2014 after two month of cyclone.

  15. SecurID

    CERN Document Server

    Now called RSA SecurID, SecurID is a mechanism developed by Security Dynamics that allows two-factor authentication for a user on a network resource. It works on the principle of the unique password mode, based on a shared secret. Every sixty seconds, the component generates a new six-digit token on the screen. The latter comes from the current time (internal clock) and the seed (SecurID private key that is available on the component, and is also from the SecurID server). During an authentication request, the SecurID server will check the entered token by performing exactly the same calculation as that performed by your component. The server knows the two information required for this calculation: the current time and the seed of your component. Access is allowed if the token calculated by the server matches the token you specified.

  16. Avicenna's Interpretation of Hudūth

    Directory of Open Access Journals (Sweden)

    Muhammet Fatih kılıç

    2011-12-01

    Full Text Available In this article, I shall deal with the concept of hudūth (origination as contextualized by Avicenna, which emerges in the context of relation between God and the world, while relating the coming into existence of the world with temporality. Avicenna discusses that there are two kinds of origination according to his classification of the celestial and sublunary world in ontology. Rational beings, celestial souls and bodies, heavenly motion and time depend on this motion are known as essential coming into existence (hudūth dhātī. These things are eternal from the point of view of temporality. There is no time difference between them and God who is the ultimate cause of them. The sublunary world consists of matter and bodies of generation and corruption. The various movements of these bodies and the time that depends on the movements are of the topic: temporal coming into existence (hudūth zamānī.

  17. Veterans Crisis Line Callers With and Without Prior VHA Service Use.

    Science.gov (United States)

    Britton, Peter C; Kopacz, Marek S; Stephens, Brady; Bossarte, Robert M

    2016-07-02

    This study examines differences between Veterans with and without prior Veterans Health Administration service use who received a clinical referral from the Veterans' Crisis Line. Differences between groups were identified using data taken from 13,444 calls and medical records. Approximately 91% of Veterans had a history of service use and 9% did not. Callers with prior service use were older, had more mental health disorders, made in-person contact more quickly, and used more outpatient mental healthcare. Those without prior service use were younger, had more mental health problems, and presented for care later. Callers with suicide-related diagnoses had high rates of service contact. These groups represent different subpopulations with unique healthcare needs and practices.

  18. TravInfo Evaluation: Traveler Response Element; TravInfo 817-1717 Caller Study; Phase 2 Results

    OpenAIRE

    Koo, Ronald; Yim, Y. B.

    2001-01-01

    TravInfo was a federally funded Field Operational Test (FOT) of the Advanced Traveler Information System (ATIS) in the San Francisco Bay Area. The general public can obtain most current traveler information through TravInfo's Traveler Advisory Telephone System (TATS) and privately offered information services including traffic Web sites. As part of the TravInfo FOT Evaluation, two waves of TATS callers were surveyed. The first wave of the TATS caller survey was conducted in April 1997. The se...

  19. Female giant panda (Ailuropoda melanoleuca) chirps advertise the caller's fertile phase.

    Science.gov (United States)

    Charlton, Benjamin D; Keating, Jennifer L; Rengui, Li; Huang, Yan; Swaisgood, Ronald R

    2010-04-07

    Although female mammal vocal behaviour is known to advertise fertility, to date, no non-human mammal study has shown that the acoustic structure of female calls varies significantly around their fertile period. Here, we used a combination of hormone measurements and acoustic analyses to determine whether female giant panda chirps have the potential to signal the caller's precise oestrous stage (fertile versus pre-fertile). We then used playback experiments to examine the response of male giant pandas to female chirps produced during fertile versus pre-fertile phases of the caller's reproductive cycle. Our results show that the acoustic structure of female giant panda chirps differs between fertile and pre-fertile callers and that male giant pandas can perceive differences in female chirps that allow them to determine the exact timing of the female's fertile phase. These findings indicate that male giant pandas could use vocal cues to preferentially associate and copulate with females at the optimum time for insemination and reveal the likely importance of female vocal signals for coordinating reproductive efforts in this critically endangered species.

  20. Female giant panda (Ailuropoda melanoleuca) chirps advertise the caller's fertile phase

    Science.gov (United States)

    Charlton, Benjamin D.; Keating, Jennifer L.; Rengui, Li; Huang, Yan; Swaisgood, Ronald R.

    2010-01-01

    Although female mammal vocal behaviour is known to advertise fertility, to date, no non-human mammal study has shown that the acoustic structure of female calls varies significantly around their fertile period. Here, we used a combination of hormone measurements and acoustic analyses to determine whether female giant panda chirps have the potential to signal the caller's precise oestrous stage (fertile versus pre-fertile). We then used playback experiments to examine the response of male giant pandas to female chirps produced during fertile versus pre-fertile phases of the caller's reproductive cycle. Our results show that the acoustic structure of female giant panda chirps differs between fertile and pre-fertile callers and that male giant pandas can perceive differences in female chirps that allow them to determine the exact timing of the female's fertile phase. These findings indicate that male giant pandas could use vocal cues to preferentially associate and copulate with females at the optimum time for insemination and reveal the likely importance of female vocal signals for coordinating reproductive efforts in this critically endangered species. PMID:19955154

  1. Perception of male caller identity in Koalas (Phascolarctos cinereus: acoustic analysis and playback experiments.

    Directory of Open Access Journals (Sweden)

    Benjamin D Charlton

    Full Text Available The ability to signal individual identity using vocal signals and distinguish between conspecifics based on vocal cues is important in several mammal species. Furthermore, it can be important for receivers to differentiate between callers in reproductive contexts. In this study, we used acoustic analyses to determine whether male koala bellows are individually distinctive and to investigate the relative importance of different acoustic features for coding individuality. We then used a habituation-discrimination paradigm to investigate whether koalas discriminate between the bellow vocalisations of different male callers. Our results show that male koala bellows are highly individualized, and indicate that cues related to vocal tract filtering contribute the most to vocal identity. In addition, we found that male and female koalas habituated to the bellows of a specific male showed a significant dishabituation when they were presented with bellows from a novel male. The significant reduction in behavioural response to a final rehabituation playback shows this was not a chance rebound in response levels. Our findings indicate that male koala bellows are highly individually distinctive and that the identity of male callers is functionally relevant to male and female koalas during the breeding season. We go on to discuss the biological relevance of signalling identity in this species' sexual communication and the potential practical implications of our findings for acoustic monitoring of male population levels.

  2. Perception of male caller identity in Koalas (Phascolarctos cinereus): acoustic analysis and playback experiments.

    Science.gov (United States)

    Charlton, Benjamin D; Ellis, William A H; McKinnon, Allan J; Brumm, Jacqui; Nilsson, Karen; Fitch, W Tecumseh

    2011-01-01

    The ability to signal individual identity using vocal signals and distinguish between conspecifics based on vocal cues is important in several mammal species. Furthermore, it can be important for receivers to differentiate between callers in reproductive contexts. In this study, we used acoustic analyses to determine whether male koala bellows are individually distinctive and to investigate the relative importance of different acoustic features for coding individuality. We then used a habituation-discrimination paradigm to investigate whether koalas discriminate between the bellow vocalisations of different male callers. Our results show that male koala bellows are highly individualized, and indicate that cues related to vocal tract filtering contribute the most to vocal identity. In addition, we found that male and female koalas habituated to the bellows of a specific male showed a significant dishabituation when they were presented with bellows from a novel male. The significant reduction in behavioural response to a final rehabituation playback shows this was not a chance rebound in response levels. Our findings indicate that male koala bellows are highly individually distinctive and that the identity of male callers is functionally relevant to male and female koalas during the breeding season. We go on to discuss the biological relevance of signalling identity in this species' sexual communication and the potential practical implications of our findings for acoustic monitoring of male population levels.

  3. 77 FR 64396 - Order of Succession for HUD Region I

    Science.gov (United States)

    2012-10-19

    ... URBAN DEVELOPMENT Order of Succession for HUD Region I AGENCY: Office of Field Policy and Management... Succession for the Boston Regional Office and its Field Offices (Region I). This Order of Succession supersedes all previous Orders of Succession for HUD Region I. DATES: Effective Date: October 9, 2012....

  4. 77 FR 64399 - Order of Succession for HUD Region V

    Science.gov (United States)

    2012-10-19

    ... URBAN DEVELOPMENT Order of Succession for HUD Region V AGENCY: Office of Field Policy and Management... Succession for the Chicago Regional Office and its Field Offices (Region V). This Order of Succession supersedes all previous Orders of Succession for HUD Region V. DATES: Effective Date: October 9, 2012. FOR...

  5. 24 CFR 882.517 - HUD review of contract compliance.

    Science.gov (United States)

    2010-04-01

    ... PERSONS WITH DISABILITIES PROGRAM) SECTION 8 MODERATE REHABILITATION PROGRAMS Special Procedures for Moderate Rehabilitation-Program Development and Operation § 882.517 HUD review of contract compliance. HUD... OF HOUSING AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT...

  6. 24 CFR 266.210 - HUD-retained review functions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false HUD-retained review functions. 266.210 Section 266.210 Housing and Urban Development Regulations Relating to Housing and Urban... Program Requirements § 266.210 HUD-retained review functions. Certain functions are retained by...

  7. 77 FR 64399 - Order of Succession for HUD Region VI

    Science.gov (United States)

    2012-10-19

    ..., Community Planning and Development. 5. Lubbock Field Office Order of Succession a. Senior Management Analyst... URBAN DEVELOPMENT Order of Succession for HUD Region VI AGENCY: Office of Field Policy and Management, HUD. ACTION: Notice of Order of Succession. SUMMARY: In this notice, the Assistant Deputy...

  8. 77 FR 64397 - Order of Succession for HUD Region III

    Science.gov (United States)

    2012-10-19

    .... Director, Community Planning and Development. 2. Baltimore Field Office Order of Succession a. Associate... URBAN DEVELOPMENT Order of Succession for HUD Region III AGENCY: Office of Field Policy and Management, HUD. ACTION: Notice of Order of Succession. SUMMARY: In this notice, the Assistant Deputy...

  9. 76 FR 71066 - HUD Draft Environmental Justice Strategy, Extension of Public Comment Period

    Science.gov (United States)

    2011-11-16

    ...: Office of Sustainable Housing and Communities, HUD. ACTION: Notice. SUMMARY: Through this notice, HUD... Sustainable Housing and Communities, Department of Housing and Urban Development, 451 7th Street SW., Room.../sustainable_housing_communities/HUD_Draft_Environmental_Justice_Strategy . As HUD noted in the October 7,...

  10. Risk Factors for Suicidal Ideation Among Telephone Crisis Hotline Callers in Japan.

    Science.gov (United States)

    Doki, Shotaro; Kaneko, Hidetoshi; Oi, Yuichi; Usami, Kazuya; Sasahara, Shinichiro; Matsuzaki, Ichiyo

    2016-11-01

    Telephone hotlines are a widely used type of suicide prevention program. The aim of this study was to clarify the risk factors for suicidal ideation by investigating its association with a number of characteristics among telephone hotline callers. Data were collected over a 10-year period from a total of 246,595 calls to Inochi No Denwa, a telephone crisis hotline in Ibaraki, Japan, and subsequently analyzed. Odds ratios for suicidal compared with nonsuicidal ideation were also calculated. About 6% of the calls to the hotline were suicide related, and about 2% of the callers had attempted suicide in the past. Odds ratios for suicidal ideation increased during winter, but no daily tendencies were evident. Those whose problems were related to their way of life were at the highest risk of suicidal ideation, followed by those with health-related concerns. We were able to identify risk factors for suicidal ideation based on an analysis of enormous amounts of data from a telephone crisis hotline in Japan. Knowledge of these risk factors is expected to lead to improvements in suicide prevention programs.

  11. Barriers to and Reasons for Treatment Initiation Among Gambling Help-line Callers.

    Science.gov (United States)

    Khayyat-Abuaita, Ula; Ostojic, Dragana; Wiedemann, Ashley; Arfken, Cynthia L; Ledgerwood, David M

    2015-08-01

    Identifying barriers to seeking treatment is essential for increasing problem gambler treatment initiation in the community, given that as few as 1 in 10 problem gamblers ever seek treatment. Further, many problem gamblers who take the initial step of contacting problem gambling help-lines do not subsequently go on to attend face-to-face treatment. There is limited research examining reasons for attending treatment among this population. This study addressed these gaps in the literature by examining barriers and attractions to treatment among callers to the State of Michigan Problem Gambling Help-line. In total, 143 callers (n = 86 women) completed the Barriers to Treatment for Problem Gambling (BTPG) questionnaire and responded to open-ended questions regarding barriers to and reasons for treatment initiation, as part of a telephone interview. Greater endorsement of barriers to treatment was associated with a lower likelihood of initiating treatment, especially perceived absence of problem and treatment unavailability. Correspondingly, problem gamblers who identified more reasons to attend treatment were more likely to attend, with positive treatment perceptions being the most influential. These findings can help get people into treatment by addressing barriers and fostering reasons for attending treatment, as well as reminding clinicians of the importance of identifying and addressing individual treatment barriers among patients with problem gambling.

  12. Who goes to treatment? Predictors of treatment initiation among gambling help-line callers.

    Science.gov (United States)

    Ledgerwood, David M; Arfken, Cynthia L; Wiedemann, Ashley; Bates, Kendrich E; Holmes, Donald; Jones, LaNeice

    2013-01-01

    Although the consequences of problem gambling can be severe, few ever seek treatment for this disorder. Problem gambling help-lines represent a crucial point of entry into the treatment system. Through brief telephone counseling, help-lines have the potential of enhancing callers' motivations to engage in longer-term treatment. We prospectively examined treatment initiation and its predictors among individuals calling a state help-line. Participants (n = 143) were assessed shortly after their initial call and re-contacted at least two months later. Overall 67% of the re-contacted help-line callers had attended at least one treatment session at the time of the follow-up interview (92.7% formal treatment and 28.1% peer-support meetings). Multivariate analysis revealed that gambling-related financial difficulties and past treatment for problem gambling (but not for mental health or substance abuse) predicted treatment initiation. Enhanced counseling focusing on motivational factors may result in better treatment engagement for some problem gamblers. Copyright © American Academy of Addiction Psychiatry.

  13. Successful I.D. Encounters.

    Science.gov (United States)

    Poorman, Margaret J.

    Instructional Development (I.D.) encounters are dependent for success on such variables as power, politics, promotion, and organizational placement. I.D. consultants must be aware of power bases or orientation of other personnel and clients, e.g., these four "power personalities" which affect their efforts in managing I.D. encounters: the gate…

  14. 24 CFR 266.25 - Limitation on HUD insurance liability.

    Science.gov (United States)

    2010-04-01

    ... party to a risk-sharing agreement with HUD with respect to the rights, benefits, and obligations of the... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS...

  15. 76 FR 62434 - HUD Draft Environmental Justice Strategy

    Science.gov (United States)

    2011-10-07

    ... URBAN DEVELOPMENT HUD Draft Environmental Justice Strategy AGENCY: Office of the Sustainable Housing and... Sustainable Housing and Communities, Department of Housing and Urban Development, 451 7th Street, SW., Room... can be found at...

  16. 24 CFR 401.405 - Restructuring Commitment review and approval by HUD.

    Science.gov (United States)

    2010-04-01

    ... condition for approval, or reject the Plan. If the Plan is rejected, HUD will inform the PAE of the reasons for rejection, and the PAE will inform the owner. HUD's rejection of the Plan is subject to...

  17. Computer assisted assessment and advice for "non-serious" 999 ambulance service callers: the potential impact on ambulance despatch

    OpenAIRE

    Dale, Jeremy; Higgins, J.; Williams, S.; Foster, T.; Snooks, Helen; Crouch, R; Hartley-Sharpe, C; Glucksman, E; Hooper, R.; George, S.

    2003-01-01

    Objective: To investigate the potential impact for ambulance services of telephone assessment and\\ud triage for callers who present with non-serious problems (Category C calls) as classified by ambulance\\ud service call takers.\\ud Design: Pragmatic controlled trial. Calls identified using priority dispatch protocols as non-serious\\ud were allocated to intervention and control groups according to time of call. Ambulance dispatch\\ud occurred according to existing procedures. During intervention...

  18. 77 FR 37696 - Notice of Proposed Information Collection: Survey and Collection of Information From HUD Lead...

    Science.gov (United States)

    2012-06-22

    ... HUD Lead Hazard Control Grantees To Support HUD and EPA Requirements To Study the Lowering of the Lead Hazard Standards and the Lead-Based Paint Standard AGENCY: Office of Healthy Homes and Lead Hazard... of selected lead hazard control grantees funded by HUD will be submitted to the Office of...

  19. 77 FR 41993 - Privacy Act of 1974; Proposed New Routine Use-HUD's Routine Use Inventory

    Science.gov (United States)

    2012-07-17

    ... URBAN DEVELOPMENT Privacy Act of 1974; Proposed New Routine Use--HUD's Routine Use Inventory AGENCY... routine uses; and (3) reduce cost and duplication of effort in the publication and maintenance of HUD's.../DEPT-63 Secretary's Correspondence Control System. HUD/DEPT-64 Congregate Housing Services Program Data...

  20. 77 FR 64396 - Order of Succession for HUD Region II

    Science.gov (United States)

    2012-10-19

    ... in office, the Regional Administrator for the Department of Housing and Urban Development or the... Indian Housing; b. Director, Community Planning and Development; c. Associate Regional Counsel, Housing... URBAN DEVELOPMENT Order of Succession for HUD Region II AGENCY: Office of Field Policy and Management...

  1. Nieuwe groeiplaats van Bijenorchis (Ophrys apifera Huds.) in Nederland

    OpenAIRE

    Horsthuis, M.A.P.; Willink, G.

    2006-01-01

    Bijenorchis neemt toe in Nederland en wordt daarbij steeds noordelijker aangetroffen. In 2005 is een geïsoleerde groeiplaats gevonden in een kalkgroeve bij Winterswijk. Ophrys apifera Huds. is spreading northwards in the Netherlands. A new isolated population has been found near Winterswijk in a limestone quarry.

  2. 24 CFR 30.20 - Ethical violations by HUD employees.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Ethical violations by HUD employees. 30.20 Section 30.20 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development CIVIL MONEY PENALTIES: CERTAIN PROHIBITED CONDUCT Violations § 30.20...

  3. 24 CFR 586.35 - HUD's review of the application.

    Science.gov (United States)

    2010-04-01

    ... Consolidated Plan(s) or any other existing housing, social service, community, economic, or other development... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false HUD's review of the application. 586.35 Section 586.35 Housing and Urban Development Regulations Relating to Housing and...

  4. Nieuwe groeiplaats van Bijenorchis (Ophrys apifera Huds.) in Nederland

    NARCIS (Netherlands)

    Horsthuis, M.A.P.; Willink, G.

    2006-01-01

    Bijenorchis neemt toe in Nederland en wordt daarbij steeds noordelijker aangetroffen. In 2005 is een geïsoleerde groeiplaats gevonden in een kalkgroeve bij Winterswijk. Ophrys apifera Huds. is spreading northwards in the Netherlands. A new isolated population has been found near Winterswijk in a lim

  5. Exploring the views and experiences of callers to the PANDA Post and Antenatal Depression Association Australian National Perinatal Depression Helpline: a cross-sectional survey.

    Science.gov (United States)

    Biggs, Laura J; Shafiei, Touran; Forster, Della A; Small, Rhonda; McLachlan, Helen L

    2015-09-07

    Anxiety and depression are common in the perinatal period. Telephone interventions, including telephone peer support and counselling, have been developed to support those experiencing perinatal mental illness. PANDA Post and Antenatal Depression Association provides support to women and men experiencing perinatal mental illness via the Australian National Perinatal Depression Helpline, encompassing both volunteer peer support and professional counselling. This study aimed to explore the experiences of callers to the Helpline. A cross-sectional survey design was used. All new callers from 1(st) May to 30(th) September 2013 were invited to participate. The survey, adapted from a previous survey of PANDA callers, included 23 questions using Likert-type scales, demographic and open-ended questions. Thematic network analysis was undertaken for responses to open-ended questions. 124 responses were received (124/405; 30% response). The majority of callers had called the Helpline regarding themselves (90%), with over one third (33%) of all callers seeking crisis support and help. Ninety-nine per cent of respondents 'agreed' or 'strongly agreed' that staff and/or volunteers understood their concerns, and 97% 'agreed' or 'strongly agreed' that overall PANDA had helped them. Callers described the PANDA service as uniquely tailored to the perinatal period, providing accessible, non-judgemental understanding and support, with a global theme from open-ended comments describing PANDA as 'a safe space to be heard and receive support without judgement'. Recommendations for service changes included increased hours of availability. Callers reported positive experiences of accessing support from the PANDA National Perinatal Depression Helpline. The Helpline was described as an accessible and acceptable telephone support for individuals experiencing perinatal mental illness. Recommendations for changes to the service included an increase in hours of operation to enable greater

  6. Understanding of and adherence to advice after telephone counselling by nurse: a survey among callers to a primary emergency out-of-hours service in Norway

    Directory of Open Access Journals (Sweden)

    Hansen Elisabeth

    2011-09-01

    Full Text Available Abstract Background To investigate how callers understand the information given by telephone by registered nurses in a casualty clinic, to what degree the advice was followed, and the final outcome of the condition for the patients. Methods The study was conducted at a large out-of-hours inter-municipality casualty clinic in Norway during April and May 2010. Telephone interviews were performed with 100 callers/patients who had received information and advice by a nurse as a sole response. Six topics from the interview guide were compared with the telephone record files to check whether the caller had understood the advice. In addition, questions were asked about how the caller followed the advice provided and the patient's outcome. Results 99 out of 100 interviewed callers stated that they had understood the nurse's advice, but interpreted from the telephone records, the total agreement for all six topics was 82.6%. 93 callers/patients stated that they followed the advice and 11 re-contacted the casualty clinic. 22 contacted their GP for the same complaints the same week, of whom five patients received medical treatment and one was hospitalised. There were significant difference between the native-Norwegian and the non-native Norwegian regarding whether they trusted the nurse (p = 0.017, and if they got relevant answers to their questions (p = 0.005. Conclusion Callers to the out-of-hours service seem to understand the advice given by the registered nurses, and a large majority of the patients did not contact their GP or other health services again with the same complaints. Practice Implication Medical and communicative training must be an important part of the continuous improvement strategy within the out-of-hour services.

  7. Access to the copper IUD as post-coital contraception: results from a mystery caller study.

    Science.gov (United States)

    Schubert, Finn D; Bishop, Erica S; Gold, Marji

    2016-11-01

    To assess access to the copper IUD as post-coital contraception (PCC) and identify barriers to obtaining this contraceptive method. We used a "mystery caller" approach to survey primary care, family planning, and Ob/Gyn clinics in nine U.S. cities, identified via online search. A single researcher called 199 clinics, assuming the role of a patient seeking the copper IUD for PCC. Using a standard script, the researcher collected information regarding access to the copper IUD and respondent's knowledge of the copper IUD's indication for PCC. The primary outcome was availability of the copper IUD as PCC. Secondary outcomes included any provision of the copper IUD, awareness of the copper IUD's indication for use as PCC, and offering accurate information regarding the copper IUD as PCC. Fisher's exact test was used to compare outcomes by clinic type. Two thirds (68%) of primary care clinics, 87% of family planning clinics, and all Ob/Gyn clinics offered the copper IUD (p<.001). Only 11% of primary care clinics, however, were aware of the copper IUD's use as PCC, as compared with 63% of family planning clinics and 24% of Ob/Gyn clinics (p<.001). Few primary care or Ob/Gyn clinics offered the copper IUD as PCC, while 49% of family planning clinics did so (p<.001). Access to the copper IUD as PCC is limited and varies by clinic type. Knowledge gaps exist regarding the use of the copper IUD as PCC, as well as regarding the general medical guidelines for copper IUD placement. A majority of primary care and Ob/Gyn clinics do not offer the copper IUD as PCC, and only about half of family planning clinics do so. Barriers included lack of knowledge, unavailability of device, unavailability of an appointment with a trained provider, and outdated IUD provision protocols. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. 24 CFR 3500.10 - One-day advance inspection of HUD-1 or HUD-1A settlement statement; delivery; recordkeeping.

    Science.gov (United States)

    2010-04-01

    ... FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT REAL ESTATE... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false One-day advance inspection of HUD-1 or HUD-1A settlement statement; delivery; recordkeeping. 3500.10 Section 3500.10 Housing and...

  9. Molecular Systematics of Polygonum minus Huds. Based on ITS Sequences

    Directory of Open Access Journals (Sweden)

    Normah Mohd Noor

    2011-11-01

    Full Text Available Plastid trnL-trnF and nuclear ribosomal ITS sequences were obtained from selected wild-type individuals of Polygonum minus Huds. in Peninsular Malaysia. The 380 bp trnL-trnF sequences of the Polygonum minus accessions were identical. Therefore, the trnL-trnF failed to distinguish between the Polygonum minus accessions. However, the divergence of ITS sequences (650 bp among the Polygonum minus accessions was 1%, indicating that these accessions could be distinguished by the ITS sequences. A phylogenetic relationship based on the ITS sequences was inferred using neighbor-joining, maximum parsimony and Bayesian inference. All of the tree topologies indicated that Polygonum minus from Peninsular Malaysia is unique and different from the synonymous Persicaria minor (Huds. Opiz and Polygonum kawagoeanum Makino.

  10. Design Study for a Low-Distortion Holographic HUD.

    Science.gov (United States)

    1982-01-01

    HUD W.S. Colburn, R.C. Fairchild RADAR AND OPTICS DIVISION ENVIRONMENTAL RESEARCH INSTITUTE OF MICHIGAN P.O. Box 8618, Ann Arbor, Michigan 48107...When Data Entered) l "Diffraction Optics Design Study" FOREWORD This report was prepared by the Electro-Optics Depart- ment, Radar and Optics...where the ray directions are reversed by the raytrace program. This design resulted in a combiner with a focal length of 193 mm, and which is predicted

  11. In-depth comparison of somatic point mutation callers based on different tumor next-generation sequencing depth data

    Science.gov (United States)

    Cai, Lei; Yuan, Wei; Zhang, Zhou; He, Lin; Chou, Kuo-Chen

    2016-11-01

    Four popular somatic single nucleotide variant (SNV) calling methods (Varscan, SomaticSniper, Strelka and MuTect2) were carefully evaluated on the real whole exome sequencing (WES, depth of ~50X) and ultra-deep targeted sequencing (UDT-Seq, depth of ~370X) data. The four tools returned poor consensus on candidates (only 20% of calls were with multiple hits by the callers). For both WES and UDT-Seq, MuTect2 and Strelka obtained the largest proportion of COSMIC entries as well as the lowest rate of dbSNP presence and high-alternative-alleles-in-control calls, demonstrating their superior sensitivity and accuracy. Combining different callers does increase reliability of candidates, but narrows the list down to very limited range of tumor read depth and variant allele frequency. Calling SNV on UDT-Seq data, which were of much higher read-depth, discovered additional true-positive variations, despite an even more tremendous growth in false positive predictions. Our findings not only provide valuable benchmark for state-of-the-art SNV calling methods, but also shed light on the access to more accurate SNV identification in the future.

  12. 76 FR 4933 - Environmental Review Procedures for Entities Assuming HUD Environmental Review Responsibilities...

    Science.gov (United States)

    2011-01-27

    ... Responsibilities; Notice of Proposed Information Collection: Comment Request AGENCY: Office of the Assistant...: Environmental Review Procedures for Entities Assuming HUD Environmental Responsibilities. OMB Control...

  13. [Comparison between two caller groups of a medical call centre in Switzerland].

    Science.gov (United States)

    Ackermann Rau, S; Zwahlen, M

    2008-05-01

    The incidence distribution of triage advice in the medical call centre Medi24 and the pattern of service utilisation were analysed with respect to two groups of callers with different insurance schemes. Individuals having contracted insurance of the Medi24 model could use the telephone consultation service of the medical call centre Medi24 (mainly part of the mandatory basic health insurance) voluntarily and free of charge whereas individuals holding an insurance policy of the Telmed model (special contract within the mandatory basic health insurance with a premium discount ranging from 8% to 12%) were obliged to have a telephone consultation before arranging an appointment with a medical doctor. A cross-sectional study was carried out in the medical call centre Medi24 based on all triage datasets of the Medi24 and Telmed groups collected during the one year period from July 1st 2005 to June 30th 2006. The distribution of the six different urgency levels within the two groups and their respective pattern of service utilisation was determined. In a multivariable logistic regression model the Odds Ratio for every enquiry originating from the Telmed group versus those originating from the Medi24 group was calculated. During a one-year period 48 388 triage requests reached the medical call centre Medi24, 56% derived from the Telmed group and 44% from the Medi24 group. Within the Medi24 group more than 25% of the individuals received self-care advice, within the Telmed group, on the other hand, only about 18% received such advice. In contrast, 27% of the Telmed triage requests but only 18% of the Medi24 triage requests resulted in the advice to make a routine appointment with a medical doctor. The probability that an individual of the Telmed group obtained the advice to go to the accident and emergency department was lower than for an individual of the Medi24 group (OR 0.77, 95% CI 0.60-0.99). Likewise, the probability of self-care advice was decreased in regard to the

  14. 75 FR 62412 - Notice of Proposed Information Collection: Comment Request; HUD-Owned Real Estate-Good Neighbor...

    Science.gov (United States)

    2010-10-08

    ... of Proposed Information Collection: Comment Request; HUD- Owned Real Estate-Good Neighbor Next Door... following information: Title of Proposal: HUD-Owned Real Estate-Good Neighbor Next Door Program. OMB Control...

  15. 75 FR 62413 - Notice of Proposed Information Collection: Comment Request; HUD-Owned Real Estate-Dollar Home...

    Science.gov (United States)

    2010-10-08

    ... of Proposed Information Collection: Comment Request; HUD- Owned Real Estate--Dollar Home Sales... also lists the following information: Title of Proposal: HUD-Owned Real Estate--Dollar Home Sales...

  16. One ID Card for the Entire Campus.

    Science.gov (United States)

    Ridenour, David P.; Ferguson, Linda M.

    1986-01-01

    The implementation by Indiana State University of a machine-readable photo ID system for their food services prompted an investigation into the available alternatives and requirements for a more efficient all-University ID card system. The new ID system is described. (AUTHOR/MLW)

  17. 24 CFR 200.937 - Supplementary specific procedural requirements under HUD building product standards and...

    Science.gov (United States)

    2010-04-01

    ... requirements under HUD building product standards and certification program for plastic bathtub units, plastic... procedural requirements under HUD building product standards and certification program for plastic bathtub... plastic water closet bowls and tanks shall be designed, assembled and tested in compliance with...

  18. 76 FR 11256 - Notice of HUD-Held Healthcare Loan Sale (HCLS 2011-1)

    Science.gov (United States)

    2011-03-01

    ... Street, SW., Washington, DC 20410-8000; telephone 202-708-2625, extension 3927. Hearing- or speech... Mortgage Loans in HCLS 2011-1. Freedom of Information Act Requests HUD reserves the right, in its sole and... HUD is obligated to disclose pursuant to the Freedom of Information Act and all regulations...

  19. 76 FR 24045 - Notice of HUD-Held Multifamily Loan Sale (MLS 2011-1)

    Science.gov (United States)

    2011-04-29

    ..., extension 3927. Hearing- or speech-impaired individuals may call 202- 708-4594 (TTY). These are not toll... Loans in MLS 2011-1. Freedom of Information Act Requests HUD reserves the right, in its sole and... HUD is obligated to disclose pursuant to the Freedom of Information Act and all regulations...

  20. 76 FR 47226 - Notice of HUD-Held Multifamily Loan Sale (MLS 2011-2)

    Science.gov (United States)

    2011-08-04

    ..., extension 3927. Hearing- or speech-impaired individuals may call 202-708-4594 (TTY). These are not toll-free... before June 30, 2011; Freedom of Information Act Requests HUD reserves the right, in its sole and... HUD is obligated to disclose pursuant to the Freedom of Information Act and all regulations...

  1. Analyzing Drivers' Attitude towards HUD System Using a Stated Preference Survey

    Directory of Open Access Journals (Sweden)

    Hongwei Guo

    2014-02-01

    Full Text Available It is very important for drivers to obtain driving information easily and efficiently. There are many advanced devices used for driving safety assistance. Of these assistance devices, the head-up display (HUD system can promote the reduction of driver's reaction time and improve spatial awareness. The drivers' attitude towards and preference for HUD system are crucial to design the functional framework and interface of HUD system. This study explored the relationships between drivers' attitude and HUD presentation image designs using stated preference data from questionnaire survey. The questionnaire included drivers' attitude towards the use of HUD and the preference for the information display zone and information display elements of the HUD. Contrastive analysis was adopted to examine the variations in drivers' attitude and preference for age and driving skills. According to the results, the participants have varying attitudes to HUD system, but most participants show relatively unified preference for the information display zone and information display elements. The results can also be used to customize a HUD presentation image which is in accordance with the drivers' feelings and preferences.

  2. 75 FR 29358 - Notice of Submission of Proposed Information Collection to OMB; Emergency Comment Request; HUD...

    Science.gov (United States)

    2010-05-25

    ... Request; HUD Office of Sustainable Housing and Communities--Sustainable Communities Regional Planning Grant Program, Public Law 111-117 AGENCY: Office of Sustainable Housing and Communities, HUD. ACTION... Notice also lists the following information: Title of Proposal: Office of Sustainable Housing and...

  3. 24 CFR 401.481 - Subsidy layering limitations on HUD funds.

    Science.gov (United States)

    2010-04-01

    ... PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.481 Subsidy layering limitations on HUD funds. (a) PAE subsidy layering certification required for Restructuring Plan. The PAE must certify to HUD that any... limit a PAE from presenting for approval a Restructuring Plan that includes project reconfiguration...

  4. 24 CFR 401.473 - HUD grants for rehabilitation under section 236(s) of NA.

    Science.gov (United States)

    2010-04-01

    ...'s evaluation of physical condition under § 401.450, as certified by the PAE. The owner must execute a grant agreement with terms and conditions acceptable to HUD. If the PAE is a State or local government, or an agency or instrumentality of such a government, the PAE and HUD may agree that the PAE...

  5. 24 CFR 906.37 - Davis-Bacon and HUD wage rate requirements.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Davis-Bacon and HUD wage rate... URBAN DEVELOPMENT PUBLIC HOUSING HOMEOWNERSHIP PROGRAMS Program Administration § 906.37 Davis-Bacon and... by the PHA, pursuant to § 906.7. Davis-Bacon or HUD-determined wage rates apply as follows:...

  6. 75 FR 80517 - HUD Multifamily Rental Project Closing Documents-Revisions and Updates Notice of Information...

    Science.gov (United States)

    2010-12-22

    ... modern real estate practice and mortgage lending laws and procedures. The August 2, 2004, notice, in turn... setting modern standards for multifamily loan documents, yet also contended that HUD's emulation is more... not revised.\\1\\ \\1\\ HUD published proposed amendments to American Institute of Architects (AIA...

  7. 24 CFR 903.25 - How does HUD ensure PHA compliance with its plan?

    Science.gov (United States)

    2010-04-01

    ... with its plan? 903.25 Section 903.25 Housing and Urban Development Regulations Relating to Housing and... compliance with its plan? A PHA must comply with the rules, standards and policies established in the plans... with its plan. If HUD should determine that a PHA is not in compliance with its plan, HUD will...

  8. 24 CFR 1000.526 - What information will HUD use for its review?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What information will HUD use for its review? 1000.526 Section 1000.526 Housing and Urban Development Regulations Relating to Housing..., Oversight and Accountability § 1000.526 What information will HUD use for its review? In reviewing...

  9. 76 FR 5393 - Notice of Submission of Proposed Information Collection to OMB; HUD Stakeholder Survey

    Science.gov (United States)

    2011-01-31

    ... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; HUD Stakeholder Survey... subject proposal. This data collection will allow HUD to collect feedback from a wide range of stakeholder groups using a brief, optional survey to be completed in person at the end of each stakeholder event....

  10. 75 FR 67992 - Notice of Proposed Information Collection: Comment Request; HUD Stakeholder Survey

    Science.gov (United States)

    2010-11-04

    ... of Proposed Information Collection: Comment Request; HUD Stakeholder Survey AGENCY: Office of the... Stakeholder Survey. OMB Control Number, if applicable: 2501-New. Description of the need for the information... groups nationwide designed to educate stakeholders about HUD initiatives and policies. This...

  11. 78 FR 75215 - Qualified Mortgage Definition for HUD Insured and Guaranteed Single Family Mortgages

    Science.gov (United States)

    2013-12-11

    ... certain clarifications and exceptions HUD is making in response to public comments. As proposed by HUD in... of exempted transactions Title II insured mortgages made by housing finance agencies and certain... relating to ratios of total monthly debt to total monthly income; (vii) the total points and fees...

  12. 24 CFR 5.233 - Mandated use of HUD's Enterprise Income Verification (EIV) System.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Mandated use of HUD's Enterprise... and Verification of Social Security Numbers and Employer Identification Numbers; Procedures for... § 5.233 Mandated use of HUD's Enterprise Income Verification (EIV) System. (a) Programs subject...

  13. 78 FR 16279 - HUD Healthcare Facility Documents: Notice Announcing Final Approved Documents and Assignment of...

    Science.gov (United States)

    2013-03-14

    ... kind of transfer, with HUD's consent. HUD notes, however, that according to the Financial Accounting... varied their references to specific provisions in the documents; sometimes the commenters referred to the provision in the healthcare facility document as sections, subsections, and paragraphs. Efforts have...

  14. DOE-HUD Initiative on Energy Efficiency in Housing: A federal partnership. Program summary report

    Energy Technology Data Exchange (ETDEWEB)

    Brinch, J. [Energetics, Inc., Columbia, MD (United States)

    1996-06-01

    One of the primary goals of the US Department of Housing and urban Development (HUD) is the expansion of home ownership and affordable housing opportunities. Recognizing that energy efficiency is a key component in an affordable housing strategy, HUD and the US Department of Energy (DOE) created the DOE-HUD Initiative on Energy Efficiency in Housing. The DOE-HUD Initiative was designed to share the results of DOE research with housing providers throughout the nation, to reduce energy costs in federally-subsidized dwelling units and improve their affordability and comfort. This Program Summary Report provides an overview of the DOE-HUD Initiative and detailed project descriptions of the twenty-seven projects carried out with Initiative funding.

  15. 78 FR 66040 - 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

    Science.gov (United States)

    2013-11-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales... collection entitled HUD-Owned Real Estate-Sales Contract and Addendums (2502-0306). HUD will republish the...

  16. 77 FR 17086 - Section 8 Housing Choice Vouchers: Revised Implementation of the HUD-VA Supportive Housing Program

    Science.gov (United States)

    2012-03-23

    ... and maintain this code on the HUD-50058. Data will also be captured in the Voucher Management System... where both PHAs have received HUD-VASH vouchers, portability moves when case management is no longer required, reallocation of HUD-VASH vouchers, and Housing Quality Standards (HQS) initial inspections....

  17. VLM Tool for IDS Integration

    Directory of Open Access Journals (Sweden)

    Cǎtǎlin NAE

    2010-03-01

    Full Text Available This paper is dedicated to a very specific type of analysis tool (VLM - Vortex Lattice Method to be integrated in a IDS - Integrated Design System, tailored for the usage of small aircraft industry. The major interest is to have the possibility to simulate at very low computational costs a preliminary set of aerodynamic characteristics for basic aerodynamic global characteristics (Lift, Drag, Pitching Moment and aerodynamic derivatives for longitudinal and lateral-directional stability analysis. This work enables fast investigations of the influence of configuration changes in a very efficient computational environment. Using experimental data and/or CFD information for a specific calibration of VLM method, reliability of the analysis may me increased so that a first type (iteration zero aerodynamic evaluation of the preliminary 3D configuration is possible. The output of this tool is basic state aerodynamic and associated stability and control derivatives, as well as a complete set of information on specific loads on major airframe components.The major interest in using and validating this type of methods is coming from the possibility to integrate it as a tool in an IDS system for conceptual design phase, as considered for development for CESAR project (IP, UE FP6.

  18. ID Barrel installed in cryostat

    CERN Multimedia

    Apsimon, R.; Romaniouk, A.

    Wednesday 23rd August was a memorable day for the Inner Detector community as they witnessed the transport and installation of the central part of the inner detector (ID-barrel) into the ATLAS detector. Many members of the collaboration gathered to witness this moment at Point 1. After years of design, construction and commissioning, the outer two detectors (TRT and SCT) of the ID barrel were moved from the SR1 cleanroom to the ATLAS cavern. The barrel was moved across the car park from building 2175 to SX1. Although only a journey of about 100 metres, this required weeks of planning and some degree of luck as far as the weather was concerned. Accelerometers were fitted to the barrel to provide real-time monitoring and no values greater than 0.1 g were recorded, fully satisfying the transport specification for this extremely precise and fragile detector. Muriel, despite her fear of heights, bravely volunteered to keep a close eye on the detector. Swapping cranes to cross the entire parking lot, while Mur...

  19. Three-dimensional system integration for HUD placement on a new tactical airlift platform: design eye point vs. HUD eye box with accommodation and perceptual implications

    Science.gov (United States)

    Harbour, Steven D.; Hudson, Jeffery A.; Zehner, Gregory F.

    2012-06-01

    The retrofitting of a cockpit with a Head-Up-Display (HUD) raises potential accommodation and perceptual issues for pilots that must be addressed. For maximum optical efficiency, the goal is to be able to place every pilot's eye into the HUD Eye Motion Box (EMB) given a seat adjustment range. Initially, the Eye Reference Point (ERP) of the EMB should theoretically be located on the aircraft's original cockpit Design Eye Point (DEP), but human postures vary, and HUD systems may not be optimally placed. In reality, there is a distribution of pilot eyes around the DEP (which is dominant eye dependent); therefore, this must be accounted for in order to obtain appropriate visibility of all of the symbology based on photonic characteristics of the HUD. Pilot size and postural variation need to be taken into consideration when positioning the HUD system to ensure proper vision of all HUD symbology in addition to meeting the basic physical accommodation requirements of the cockpit. The innovative process and data collection methods for maximizing accommodation and pilot perception on a new "tactical airlift" platform are discussed as well as the related neurocognitive factors and the effects of information display design on cognitive phenomena.

  20. L’idéologie

    Directory of Open Access Journals (Sweden)

    Paul Aron

    2007-02-01

    Full Text Available De Marx à BourdieuJugée essentielle dans les années septante, déclinée en colloques, ouvrages polémiques ou encyclopédiques divers, rythmée par les interventions théoriques de penseurs comme Antonio Gramsci, que l’on commençait à traduire en français, Louis Althusser, Lucien Sève ou Robert Fossaert, la problématique de l’idéologie a mobilisé les esprits à un point tel que le silence qui l’entoure aujourd’hui peut légitimement surprendre.Je commencerai par situer cette notion dans son cadre hi...

  1. HuD Regulates Coding and Noncoding RNA to Induce APP→Aβ Processing

    Directory of Open Access Journals (Sweden)

    Min-Ju Kang

    2014-06-01

    Full Text Available The primarily neuronal RNA-binding protein HuD is implicated in learning and memory. Here, we report the identification of several HuD target transcripts linked to Alzheimer’s disease (AD pathogenesis. HuD interacted with the 3′ UTRs of APP mRNA (encoding amyloid precursor protein and BACE1 mRNA (encoding β-site APP-cleaving enzyme 1 and increased the half-lives of these mRNAs. HuD also associated with and stabilized the long noncoding (lncRNA BACE1AS, which partly complements BACE1 mRNA and enhances BACE1 expression. Consistent with HuD promoting production of APP and APP-cleaving enzyme, the levels of APP, BACE1, BACE1AS, and Aβ were higher in the brain of HuD-overexpressing mice. Importantly, cortex (superior temporal gyrus from patients with AD displayed significantly higher levels of HuD and, accordingly, elevated APP, BACE1, BACE1AS, and Aβ than did cortical tissue from healthy age-matched individuals. We propose that HuD jointly promotes the production of APP and the cleavage of its amyloidogenic fragment, Aβ.

  2. Multi-tool design and analysis of an automotive HUD

    Science.gov (United States)

    Irving, Bruce; Hasenauer, David; Mulder, Steve

    2016-10-01

    Design and analysis of an optical system is often a multidisciplinary task, and can involve the use of specialized software packages for imaging, mechanics, and illumination. This paper will present a case study on the design and analysis of a basic heads-up display (HUD) for automotive use. The emphasis will be on the special requirements of a HUD visual system and on the tools and techniques needed to accomplish the design. The first section of this paper will present an overview of the imaging design using commercially available imaging design software. Topics addressed in this section include modeling the windshield, visualizing the imaging performance, using constraints and freeform surfaces to improve the system, and meeting specific visual performance specifications with design/analysis methods. The second section will address the use of a CAD program to design a basic mechanical structure to support and protect the optics. This section will also discuss some of the issues and limitations involved in translating data between a CAD program and a lens design or illumination program. Typical issues that arise include the precision of optical surface prescriptions, surface and material properties, and the management of large data files. In the final section, the combined optical and mechanical package will be considered, using an illumination design program for stray light analysis. The stray light analysis will be directed primarily toward finding, visualizing, and quantifying unexpected ray paths. Techniques for sorting optical ray paths by path length, power, and elements or materials encountered will be discussed, along with methods for estimating the impact of stray light on the optical system performance.

  3. Tinjauan Desain Website kemlu.go.id

    Directory of Open Access Journals (Sweden)

    Danu Widhyatmoko

    2013-03-01

    Full Text Available Review of kemlu.go.id website design is a research report on Kemlu.go.id website design. Kemlu.go.id website aims to be the information gateway of Ministry of Foreign Affairs, and also as guidelines of foreign politic policies of Republic of Indonesia. The review had been accomplished by using analytical method based on the "Nine Essential Principles for Good Web Design" developed by Collis Ta'eed (2007. At the end of the article, several recommendations in developing kemlu.go.id website are presented to create better appearance.

  4. Minimal intervention delivered by 2-1-1 information and referral specialists promotes smoke-free homes among 2-1-1 callers: a Texas generalisation trial.

    Science.gov (United States)

    Mullen, Patricia Dolan; Savas, Lara S; Bundy, Łucja T; Haardörfer, Regine; Hovell, Mel; Fernández, Maria E; Monroy, Jo Ann A; Williams, Rebecca S; Kreuter, Matthew W; Jobe, David; Kegler, Michelle C

    2016-10-01

    Replication of intervention research is reported infrequently, limiting what we know about external validity and generalisability. The Smoke Free Homes Program, a minimal intervention, increased home smoking bans by United Way 2-1-1 callers in randomised controlled trials in Atlanta, Georgia and North Carolina. Test the programme's generalisability-external validity in a different context. A randomised controlled trial (n=508) of English-speaking callers from smoking-discordant households (≥1 smoker and ≥1 non-smoker). 2-1-1 Texas/United Way HELPLINE call specialists serving the Texas Gulf Coast recruited callers and delivered three mailings and one coaching call, supported by an online tracking system. Data collectors, blind to study assignment, conducted telephone interviews 3 and 6 months postbaseline. At 3 months, more intervention households reported a smoke-free home (46.6% vs 25.4%, pspeaking Latinos, support programme generalisability and convey evidence of external validity. Our recruitment experience indicates that site-specific adjustments might improve recruitment efficiency and reach. NCT02097914, Results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  5. Habitat Use Database - Groundfish Essential Fish Habitat (EFH) Habitat Use Database (HUD)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Habitat Use Database (HUD) was specifically designed to address the need for habitat-use analyses in support of groundfish EFH, HAPCs, and fishing and nonfishing...

  6. 76 FR 72211 - Notice of Proposed Information Collection: Comment Request, HUD-Administered Small Cities Program...

    Science.gov (United States)

    2011-11-22

    ... provides HUD with financial and physical development status of each activity funded. These reports are used... technology, e.g., permitting electronic submission of responses. This Notice also lists the...

  7. Flight Test of a Head-Worn Display as an Equivalent-HUD for Terminal Operations

    Science.gov (United States)

    Shelton, K. J.; Arthur, J. J., III; Prinzel, L. J., III; Nicholas, S. N.; Williams, S. P.; Bailey, R. E.

    2015-01-01

    Research, development, test, and evaluation of flight deck interface technologies is being conducted by NASA to proactively identify, develop, and mature tools, methods, and technologies for improving overall aircraft safety of new and legacy vehicles operating in the Next Generation Air Transportation System (NextGen). Under NASA's Aviation Safety Program, one specific area of research is the use of small Head-Worn Displays (HWDs) as a potential equivalent display to a Head-up Display (HUD). Title 14 of the US CFR 91.175 describes a possible operational credit which can be obtained with airplane equipage of a HUD or an "equivalent"' display combined with Enhanced Vision (EV). A successful HWD implementation may provide the same safety and operational benefits as current HUD-equipped aircraft but for significantly more aircraft in which HUD installation is neither practical nor possible. A flight test was conducted to evaluate if the HWD, coupled with a head-tracker, can provide an equivalent display to a HUD. Approach and taxi testing was performed on-board NASA's experimental King Air aircraft in various visual conditions. Preliminary quantitative results indicate the HWD tested provided equivalent HUD performance, however operational issues were uncovered. The HWD showed significant potential as all of the pilots liked the increased situation awareness attributable to the HWD's unique capability of unlimited field-of-regard.

  8. Outside scene obscuration by a millimeter-wave radar image presented on a HUD

    Science.gov (United States)

    Huntoon, Richard B.; Rand, Timothy W.; Lapis, Mary Beth

    1995-06-01

    We investigated whether a raster image on a Head-Up Display (HUD) might interfere with runway recognition during a low-visibility (CAT II and IIIa) approach. The primary reason for incorporating a HUD into the flight deck is to allow the pilot to observe instrument information while maintaining a view of the outside scene. The raster image could, however, obscure the outside scene, leaving the pilot unaware that the approach or runway lights are visible. In our HUD lab, twenty-one subjects were asked to observe a simulated outside scene through a HUD and indicate when they first saw runway approach lights. Each subject was presented 12 data runs with a simulated 35-GHz raster radar image and stroke symbology simultaneously presented on the HUD, and 12 data runs with only stroke symbology on the HUD. Each run was conducted under simulated fog conditions of either 700-ft Runway Visual Range (RVR) or 1200-ft RVR. We found that the presence of the radar image decreased the recognition range by 24 percent (z equals 5.71, p < 0.001). Subjective comments by the study participants show that the radar serves as a valuable aid in confirming flight path alignment with the runway under low-visibility conditions.

  9. DNS ID Covert Channel based on Lower Bound Steganography for Normal DNS ID Distribution

    Directory of Open Access Journals (Sweden)

    Abdulrahman H. Altalhi

    2011-11-01

    Full Text Available The covert channel is a method used to send secret data within a communication channel in unauthorized ways. This is performed by exploiting the weaknesses in packet or network communications with the intention to hide the existence of a covert communication. The DNS identification (DNS ID method has been exploited by Thyer. However, the major problem in Thyers implementation is that the encrypted cipher was directly inserted as a DNS ID value, which is abnormal, compared to the normal DNS ID distribution. We have overcome this problem through the application of Steganography to insert the cipher value into the DNS ID. The data set test for normal DNS ID is taken from MAWI. We tested four different message lengths and plotted the distribution graph. We found that the proposed result is normal compared to normal distribution of the DNS ID. Therefore, this method produces a normal distribution for DNS ID covert channel.

  10. Development Of HUD Combiner For Automotive Windshield Application

    Science.gov (United States)

    Hattori, Akimasa; Makita, Kensuke; Okabayashi, Shigeru

    1989-12-01

    The head-up display system (HUM) has been developed for the windshield of Nissan Motor's passenger car, '88 model of Silvia (240SX) and '89 model of Maxima. HUD consists of a projector with high brightness VFT and a combiner which is a light-selective reflective film applied on the surface of ' e windshield. The system provides nice display legibility of speed in a three-digit reap at the position more than one meter far from driver's eye even under the bright sunlight. In this report, we present the optical properties and manufacturing process of the advanced combiner. The combiner has to have high transmittance as well as high reflectance so that a driver can see both foreground object and display reading at the same time. The optical design for the combiner is based on the concepts: (a) Visible light transmittance has to be 70% or more in accordance with a legal requirement, and (b) taking both peak wavelengths of Vim' and sensitivity characteristics of human eyes into consideration, 530nm of wave length is chosen as a reflective light. The combiner consists of a dielectric thin layer of Ti02-Si02 system. Its basic structure is decided by simulation with matrix method of the resultant waves. The coating film is applied on the restricted area of the forth surface of laminated windshield by newly developed solgel printing process using a metal alkoxide solution with a relatively long storage life.

  11. Inhibitor of differentiation 4 (ID4): From development to cancer.

    Science.gov (United States)

    Patel, Divya; Morton, Derrick J; Carey, Jason; Havrda, Mathew C; Chaudhary, Jaideep

    2015-01-01

    Highly conserved Inhibitors of DNA-Binding (ID1-ID4) genes encode multi-functional proteins whose transcriptional activity is based on dominant negative inhibition of basic helix-loop-helix (bHLH) transcription factors. Initial animal models indicated a degree of compensatory overlap between ID genes such that deletion of multiple ID genes was required to generate easily recognizable phenotypes. More recently, new model systems have revealed alterations in mice harboring deletions in single ID genes suggesting complex gene and tissue specific functions for members of the ID gene family. Because ID genes are highly expressed during development and their function is associated with a primitive, proliferative cellular phenotype there has been significant interest in understanding their potential roles in neoplasia. Indeed, numerous studies indicate an oncogenic function for ID1, ID2 and ID3. In contrast, the inhibitor of differentiation 4 (ID4) presents a paradigm shift in context of well-established role of ID1, ID2 and ID3 in development and cancer. Apart from some degree of functional redundancy such as HLH dependent interactions with bHLH protein E2A, many of the functions of ID4 are distinct from ID1, ID2 and ID3: ID4 proteins a) regulate distinct developmental processes and tissue expression in the adult, b) promote stem cell survival, differentiation and/or timing of differentiation, c) epigenetic inactivation/loss of expression in several advanced stage cancers and d) increased expression in some cancers such as those arising in the breast and ovary. Thus, in spite of sharing the conserved HLH domain, ID4 defies the established model of ID protein function and expression. The underlying molecular mechanism responsible for the unique role of ID4 as compared to other ID proteins still remains largely un-explored. This review will focus on the current understanding of ID4 in context of development and cancer. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Id-1 and Id-2 genes and products as markers of epithelial cancer

    Energy Technology Data Exchange (ETDEWEB)

    Desprez, Pierre-Yves (El Cerrito, CA); Campisi, Judith (Berkeley, CA)

    2011-10-04

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  13. Id-1 and Id-2 genes and products as markers of epithelial cancer

    Science.gov (United States)

    Desprez, Pierre-Yves [El Cerrito, CA; Campisi, Judith [Berkeley, CA

    2011-10-04

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  14. Id-1 and Id-2 genes and products as markers of epithelial cancer

    Science.gov (United States)

    Desprez, Pierre-Yves; Campisi, Judith

    2008-09-30

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  15. Frequency-modulated second elements of two-element alarm calls do not enhance discrimination of callers in three Eurasian ground squirrels

    Institute of Scientific and Technical Information of China (English)

    Irena SCHNEIDEROV(A)

    2012-01-01

    Alarm calls of the European Spermophilus citellus (EGS),Taurus S.taurensis (TGS) and Anatolian S.xanthoprymnus (AGS) ground squirrels share the same basic structure.They are tonal sounds consisting primarily of two different elements.The first element,often produced without the second element,has limited frequency modulation,while the second element is more frequency modulated.The present study examined whether this frequency-modulated element enhances the individual distinctiveness of calls,allowing calls to be ascribed with greater confidence to individual callers of the three species.Cross-validated discriminant function analysis (DFA) based on five acoustic parameters of the first element successfully classified calls to correct individuals (EGS:90%,TGS:98%,AGS:96%).Cross-validated DFA based on five acoustic parameters of the second element was also successful in classifications (EGS:88%,TGS:86%,AGS:96%),though discrimination of callers based on parameters of the second versus first element was the same for the AGS,lower for the EGS and significantly lower for the TGS.Cross-validated DFA based on five acoustic parameters of two-element calls also successfully classified calls to correct individuals (EGS:93%,TGS:98%,AGS:97%),though did not improve the extent to which calls could be classified to individuals beyond that based on the first element alone.Thus,the second element does not enhance the individual distinctiveness of calls,but may convey other information such as the location of the caller.

  16. Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances.

    Directory of Open Access Journals (Sweden)

    Qingshi Zhao

    Full Text Available The Inhibitor of DNA Binding (Id proteins play a crucial role in regulating hematopoiesis and are known to interact with E proteins and the bHLH family of transcription factors. Current efforts seek to elucidate the individual roles of Id members in regulating hematopoietic development and specification. However, the nature of their functional redundancies remains elusive since ablation of multiple Id genes is embryonically lethal. We developed a model to test this compensation in the adult. We report that global Id3 ablation with Tie2Cre-mediated conditional ablation of Id1 in both hematopoietic and endothelial cells (Id cDKO extends viability to 1 year but leads to multi-lineage hematopoietic defects including the emergence of anemia associated with defective erythroid development, a novel phenotype unreported in prior single Id knockout studies. We observe decreased cell counts in the bone marrow and splenomegaly to dimensions beyond what is seen in single Id knockout models. Transcriptional dysregulation of hematopoietic regulators observed in bone marrow cells is also magnified in the spleen. E47 protein levels were elevated in Id cDKO bone marrow cell isolates, but decreased in the erythroid lineage. Chromatin immunoprecipitation (ChIP studies reveal increased occupancy of E47 and GATA1 at the promoter regions of β-globin and E2A. Bone marrow transplantation studies highlight the importance of intrinsic Id signals in maintaining hematopoietic homeostasis while revealing a strong extrinsic influence in the development of anemia. Together, these findings demonstrate that loss of Id compensation leads to dysregulation of the hematopoietic transcriptional network and multiple defects in erythropoietic development in adult mice.

  17. 76 FR 71593 - Notice of HUD-Held Multifamily and Healthcare Loan Sale (MHLS 2012-1)

    Science.gov (United States)

    2011-11-18

    ...) 708-2625, extension 3927. Hearing- or speech-impaired individuals may call (202) 708-4594 (TTY). These... review of the Mortgage Loans will be provided in the BIP. Mortgage Loan Sale Policy HUD reserves the... Notice This notice applies to MHLS 2012-1 and does not establish HUD's policy for the sale of...

  18. 78 FR 70957 - 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate Good Neighbor Next Door...

    Science.gov (United States)

    2013-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate Good Neighbor... Information Collection: HUD Real Estate Owned Good Neighbor Next Door. OMB Approval Number: 2502-0570. Type of...

  19. 76 FR 5819 - Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate-Dollar Home...

    Science.gov (United States)

    2011-02-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate... following information: Title of Proposal: HUD-Owned Real Estate--Dollar Home Sales Program. OMB approval...

  20. 78 FR 64145 - 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

    Science.gov (United States)

    2013-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales... Collection: HUD-Owned Real Estate--Sales Contract and Addendums. OMB Approval Number: 2502-0306. Type of...

  1. 75 FR 44006 - Notice of Submission of Proposed Information Collection to OMB, HUD-Owned Real Estate-Sales...

    Science.gov (United States)

    2010-07-27

    ... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB, HUD-Owned Real Estate... Department is soliciting public comments on the subject proposal. The respondents are real estate listing...: Title of Proposal: HUD-Owned Real Estate--Sales Contract and Addendums. OMB Approval Number: 2502-0306...

  2. 76 FR 6488 - Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate-Good...

    Science.gov (United States)

    2011-02-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; HUD-Owned Real Estate... responses. This Notice Also Lists the Following Information Title of Proposal: HUD-Owned Real Estate--Good...

  3. 24 CFR 964.320 - HUD Policy on training, employment, contracting and subcontracting of public housing residents.

    Science.gov (United States)

    2010-04-01

    ... TENANT OPPORTUNITIES IN PUBLIC HOUSING Family Investment Centers (FIC) Program § 964.320 HUD Policy on... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HUD Policy on training, employment, contracting and subcontracting of public housing residents. 964.320 Section 964.320 Housing and...

  4. 78 FR 13885 - Notice of HUD-Held Multifamily & Healthcare Loan Sale, Second Offering (MHLS 2013-1)

    Science.gov (United States)

    2013-03-01

    ... of sale of mortgage loans. SUMMARY: This notice announces HUD's intention to sell certain...). These are not toll-free numbers. SUPPLEMENTARY INFORMATION: HUD announces its intention to sell, in a..., the bidder's deposit will be non-refundable and will be applied toward the purchase price....

  5. 77 FR 30307 - Notice of HUD-Held Multifamily and Healthcare Loan Sale (MHLS 2012-2)

    Science.gov (United States)

    2012-05-22

    ...; telephone 202-708-2625, extension 3927. Hearing- or speech-impaired individuals may call 202-708-4594 (TTY... to submit bids on the Mortgage Loans in MHLS 2012-2. Freedom of Information Act Requests HUD reserves... to disclose any information that HUD is obligated to disclose pursuant to the Freedom of...

  6. 76 FR 71067 - Privacy Act of 1974; Notification To Delete and Create a New System of Records, “HUD/FHA Lender...

    Science.gov (United States)

    2011-11-16

    ... maintained by HUD's Lender Approval Files System of Records Notice (SORN) and will fully automate the manual.../P278), formerly ``HUD/FHA Lender Approval Files.'' SYSTEM LOCATION: LEAP is hosted on HUD servers... URBAN DEVELOPMENT Privacy Act of 1974; Notification To Delete and Create a New System of Records,...

  7. 24 CFR 1000.332 - Will data used by HUD to determine an Indian tribe's or TDHE's formula allocation be provided to...

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES Allocation Formula § 1000.332 Will data used by HUD... before the allocation? Yes. HUD shall provide notice to the Indian tribe or TDHE of the data to be used... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Will data used by HUD to...

  8. Noorteadlased kaitsesid doktoritöid

    Index Scriptorium Estoniae

    2002-01-01

    13. sept. 2002.a. kaitsesid TPÜ-s doktoritöid Mare Leino ("Sotsiaalsed probleemid koolis ja õpetaja toimetulek" ja Maaris Raudsepp ("Loodussäästlikkus kui regulatiivne idee: sotsiaal-psühholoogiline analüüs")

  9. Independence Day 2004 (ID04) / Raul Hindov

    Index Scriptorium Estoniae

    Hindov, Raul

    2004-01-01

    Ülevaade 20.-22. veebruarini 2004 toimunud kaugluurepatrullide rännaku ja sõdurioskuste kompleksõppusest ID04 (Independence Day 2004 - Iseseisvuspäev 2004), millel osales 25 patrullvõistlusteks valmistuvat meest ja naist

  10. Independence Day 2004 (ID04) / Raul Hindov

    Index Scriptorium Estoniae

    Hindov, Raul

    2004-01-01

    Ülevaade 20.-22. veebruarini 2004 toimunud kaugluurepatrullide rännaku ja sõdurioskuste kompleksõppusest ID04 (Independence Day 2004 - Iseseisvuspäev 2004), millel osales 25 patrullvõistlusteks valmistuvat meest ja naist

  11. Selection of starter cultures for idli batter fermentation and their effect on quality of idlis.

    Science.gov (United States)

    Sridevi, J; Halami, Prakash M; Vijayendra, S V N

    2010-10-01

    Idli batter samples were prepared using lactic starter cultures like Pediococcus pentosaceus (Pp), Enterococcus faecium MTCC 5153 (Ef), Ent. faecium (IB2 Ef-IB2), individually, along with the yeast culture, Candida versatilis (Cv). Idli batter prepared using Ef and Ef-IB2 cultures gave better results, when evaluated for the rise in batter volume (80 ml), level of CO2 production (23.8%), titratable acidity 2.4-3.5% (lactic acid) and pH 4.3-4.4. Storage stability of batter made with selected starter cultures was determined by analyzing the idlis prepared using the batter stored for 1 and 5 days for texture, nutrient composition and sensory quality. Slight variations in the results were seen among the idlis of different combination of cultures, whereas these results are better than that of the idlis made using naturally fermented idli batter. Sensory profile of idlis prepared using starter cultures had a higher score (3.9-4.4) compared to the control (3.6) for overall acceptability.

  12. 24 CFR 200.955 - Supplementary specific requirements under the HUD building product standard and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standard and certification program for fenestration products (windows and... fenestration products (windows and doors). (a) Applicable standards. (1) All windows and doors shall be... (AAMA) standard, AAMA/NWWDA 101/I.S.2-97 Voluntary Specifications for Aluminum, Vinyl (PVC) and...

  13. 75 FR 423 - Notice of Availability: HUD Real Estate Settlement Procedures Act (RESPA) Handbook

    Science.gov (United States)

    2010-01-05

    ... [Federal Register Volume 75, Number 2 (Tuesday, January 5, 2010)] [Notices] [Page 423] [FR Doc No: E9-31304] DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5369-N-01] Notice of Availability: HUD Real Estate Settlement Procedures Act (RESPA) Handbook AGENCY: Office of the Assistant...

  14. 76 FR 24507 - HUD Multifamily Rental Project Closing Documents: Notice Announcing Final Approved Documents and...

    Science.gov (United States)

    2011-05-02

    ... available mechanism to review public comments submitted in response to the August 2, 2004, notice. Therefore... Mae Handbook 5500.3 Rev. 1 10.01.09 p16-7). \\5\\ The Ginnie Mae Guides are available on Ginnie Mae's... more certain legal mechanisms for enforcing HUD's statutory, regulatory, and program requirements...

  15. 75 FR 12775 - Notice of HUD-Held Multifamily and Healthcare Loan Sale

    Science.gov (United States)

    2010-03-17

    ..., SW., Washington, DC 20410-8000; telephone number 202-708-2625, extension 3927. Hearing- or speech...-1. Freedom of Information Act Requests HUD reserves the right, in its sole and absolute discretion... disclose pursuant to the Freedom of Information Act and all regulations promulgated thereunder. Scope of...

  16. 77 FR 70179 - Notice of HUD-Held Multifamily and Healthcare Loan Sale

    Science.gov (United States)

    2012-11-23

    ... SW., Washington, DC 20410-8000; telephone 202-708-2625, extension 3927. Hearing- or speech-impaired...-1. Freedom of Information Act Requests HUD reserves the right, in its sole and absolute discretion... disclose pursuant to the Freedom of Information Act and all regulations promulgated there under. Scope of...

  17. 78 FR 44582 - Notice of HUD-Held Multifamily & Healthcare Loan Sale, (MHLS 2013-2)

    Science.gov (United States)

    2013-07-24

    ... Street SW., Washington, DC 20410-8000; telephone 202-708-2625, extension 3927. Hearing- or speech.... Freedom of Information Act Requests HUD reserves the right, in its sole and absolute discretion, to... disclose pursuant to the Freedom of Information Act and all regulations promulgated thereunder. Scope of...

  18. 24 CFR 245.419 - Initial submission of materials to HUD: Major capital additions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Initial submission of materials to HUD: Major capital additions. 245.419 Section 245.419 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL...

  19. 24 CFR 245.415 - Submission of materials to HUD: Timing of submission.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Submission of materials to HUD: Timing of submission. 245.415 Section 245.415 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING...

  20. 75 FR 3543 - HUD Multifamily Rental Project Closing Documents: Proposed Revisions and Updates and Notice of...

    Science.gov (United States)

    2010-01-21

    ... Mortgage Insurance Premium that appears in section G of HUD-92264 attributable to the construction period... factual matter rather than a legal opinion. 14. Provided for signature of the opinion by an authorized... ``premium'' or ``marketing gain,'' is the amount of additional funds, over and above the mortgage...

  1. 24 CFR 200.944 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... excluding any floor finishes. Copies of the APA Standard may be obtained from the American Plywood... accordance with procedures set forth in APA PRP-108 Performance Standards and Policies for Structural-Use... under the HUD building product standards and certification program for plywood and other...

  2. 78 FR 17938 - Notice of Proposed Information; Collection for Public Comment; Recordkeeping for HUD's Continuum...

    Science.gov (United States)

    2013-03-25

    ...; Division B of this law is the HEARTH Act. As amended by the HEARTH Act, Subpart C of the McKinney-Vento... McKinney-Vento Homeless Assistance Act (42 U.S.C. 11371 et seq.). The HEARTH Act was designed to..., continues HUD's implementation of the HEARTH Act. This rule establishes the regulatory framework for...

  3. 78 FR 78998 - 60-Day Notice of Proposed Information Collection: HUD Environmental Review Online System (HEROS)

    Science.gov (United States)

    2013-12-27

    ....gov . This phone number is not toll-free. Hearing or speech-impaired individuals may access this...-3400 ] (this is not a toll-free number) or email at Colette.Pollard@hud.gov for a copy of the proposed forms or other available information. Persons with hearing or speech impairments may access this number...

  4. 24 CFR 1715.50 - Advertising disclaimers; subdivisions registered and effective with HUD.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Advertising disclaimers... REGISTRATION PROGRAM) PURCHASERS' REVOCATION RIGHTS, SALES PRACTICES AND STANDARDS Advertising Disclaimers § 1715.50 Advertising disclaimers; subdivisions registered and effective with HUD. (a) The following...

  5. 78 FR 74157 - Notice of HUD-Held Multifamily Loan Sale (MLS 2014-1)

    Science.gov (United States)

    2013-12-10

    .... Hearing- or speech-impaired individuals may call 202-708-4594 (TTY). These are not toll-free numbers... to submit bids on the Mortgage Loans in this offering of MLS 2014-1. Freedom of Information Act... information that HUD is obligated to disclose pursuant to the Freedom of Information Act and all...

  6. Comparing Outcomes for Los Angeles County's HUD-Assisted and Unassisted CalWORKS Leavers.

    Science.gov (United States)

    Verma, Nandita; Hendra, Richard

    The impact of supplemental assistance from the U.S. Department of Housing and Urban Development (HUD) on CalWORKs leavers was examined in a study of CalWORKs recipients in Los Angeles County, California, who stopped receiving welfare benefits in the third quarter of 1998. Two groups received federal housing assistance at the time of exit from…

  7. 24 CFR 985.3 - Indicators, HUD verification methods and ratings.

    Science.gov (United States)

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT SECTION 8 MANAGEMENT ASSESSMENT PROGRAM (SEMAP) General § 985.3 Indicators... assess PHA Section 8 management. HUD will use the verification method identified for each indicator in... in Federal awards and whose Section 8 programs are not audited by an independent auditor (IA),...

  8. 24 CFR 3500.4 - Reliance upon rule, regulation or interpretation by HUD.

    Science.gov (United States)

    2010-04-01

    ..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT REAL ESTATE SETTLEMENT PROCEDURES ACT § 3500.4 Reliance upon rule... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Reliance upon rule, regulation or interpretation by HUD. 3500.4 Section 3500.4 Housing and Urban Development Regulations Relating to Housing...

  9. 24 CFR 5.109 - Equal Participation of Religious Organizations in HUD Programs and Activities.

    Science.gov (United States)

    2010-04-01

    ... the definition, practice, and expression of its religious beliefs, provided that it does not engage in... program beneficiary or prospective program beneficiary on the basis of religion or religious belief. (g) Acquisition, construction, and rehabilitation of structures. HUD funds may not be used for the...

  10. 78 FR 5185 - Guidance for Industry and Food and Drug Administration Staff; Humanitarian Use Device (HUD...

    Science.gov (United States)

    2013-01-24

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; Humanitarian Use Device (HUD) Designations; Availability AGENCY: Food and Drug Administration, HHS. ACTION... public comment ``Draft Guidance for Industry and Food and Drug Administration Staff on Humanitarian...

  11. 自杀高危来电的特征及心理危机热线干预%Characteristics of high-risk suicidal callers and intervention of psychological crisis hotline

    Institute of Scientific and Technical Information of China (English)

    吴素英; 廖震华; 刘发荣; 温园园

    2014-01-01

    目的::了解自杀高危来电的特征及心理危机热线干预效果。方法:选取厦门市心理危机干预热线的来电资料,符合高危条件的来电共140例。应用自编抑郁症状筛查量表、自杀危险评估量表分别进行评估抑郁状况、自杀危险程度,对评估出的高危来电进行24h、1周及1月3次随访,并进行干预效果比较。结果:140例来电中,男性56例,女性84例;平均年龄(29.62依8.32)岁;有职业86例,无业54例;已婚58例,未婚70例,其他12例。既往有明确精神科诊断者33例,其中抑郁症22例,精神分裂症10例。来电咨询问题的前三位为家庭关系问题、恋爱及人际关系问题、精神疾病问题。不同性别、年龄和婚姻状况的咨询问题分布差异均有统计学意义(均 P<0.05)。高危来电3次随访结果显示,来电者的自杀死亡决心程度降低,每次干预后死亡决心程度均较前次降低(均 P<0.05)。结论:心理危机干预热线在一定程度上可降低高危来电者自杀危险程度,但仍需加强后续随访干预,以提高干预效果。%Objective:To describe the characteristics of callers with high suicide risk and intervention effectiveness of psycho-logical crisis hotline. Methods:Among the callers of Xiamen psychological crisis hotline, 140 cases with high suicide risk were select-ed to be analyzed. A screening instrument for depression and suicide risk were used to assess the depression and suicide risk. The cal-lers with high suicide risk were followed-up within 24 hours, 1 week and 1 month after the calling. The intervention effectiveness was compared. Results: Among the 140 callers, 56 callers were male and 84 callers were female. The average age was (29. 62±8. 32) years. 86 callers were employed, while 54 callers were unemployed; 58 callers were married, while 70 callers were unmarried; 12 cal-ler were others. Among 33 caller with a psychiatric diagnosis, 22

  12. IDS in Telecommunication Network using PCA

    Directory of Open Access Journals (Sweden)

    T. K. Abdelhamid

    2013-07-01

    Full Text Available Data Security has become a very serious part of any organizational information system.Internet threatshavebecome moreintelligentso itcan deceivethe basic security solutions such as firewalls and antivirusscanners.To enhance the overall security of the networkan additional security layer such asintrusiondetection system(IDShas to be added.The anomaly detection IDSisa typeof IDS thatcandifferentiatebetweennormal and abnormal in thedata monitored. This paper proposes two types of IDS, oneof themcanbeusedasa network intrusion detection system(NIDS with overallsuccess (0.9161 and highdetection rate (0.9288 andtheothertypecanalso beusedasa host intrusion detection system(HIDS withoverall success (0.8493 and very high detection rate (0.9628using NSL-KDD data set

  13. Haro sur l’idéologie

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Bertrand

    2007-02-01

    Full Text Available Consacrer une journée d’études à la question de l’idéologie dans les études littéraires, ce n’est pas réhabiliter une notion qui a porté toute la tradition sociocritique, de Lukàcs à Hamon, en passant par Barthes, Dubois, Duchet et tant d’autres, en référence à la célèbre définition qu’en avait donné Althusser dans Positions. Ce n’est pas non plus enterrer très idéologiquement une notion dont on découvrirait, en cette ère de postmodernité, l’incongruité opérationnelle. C’est pour le moins fai...

  14. Tarbijakaitse ei sekku esialgu ID-pileti projekti / Urmas Seaver

    Index Scriptorium Estoniae

    Seaver, Urmas, 1973-

    2004-01-01

    Tallinna ID-pileti müügil teenustasu võtmist arvustanud riigi tarbijakaitse amet ei sekku esialgu käivituvasse projekti, sest linnavalitsus võimaldab osta kahest teeninduspunktist ID-piletit ka teenustasuta

  15. Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory.

    Science.gov (United States)

    Omilusik, Kyla D; Shaw, Laura A; Goldrath, Ananda W

    2013-10-01

    Upon infection, CD8(+) T cells proliferate and differentiate into armed effector cells capable of eliminating the assaulting pathogen. Although the majority of the antigen-specific T cells will die as the immune response wanes, a few will survive indefinitely to establish the memory population and provide long-lived protection against reinfection. E protein transcription factors and their inhibitors, ID proteins, operate to balance expression of genes that control CD8(+) T cell differentiation through this process. Here, we discuss the role of ID2 and ID3 in promoting the generation and survival of effector and memory populations, particularly highlighting their reciprocal roles in shaping the CD8(+) T cell response unique to the inflammatory milieu. We further examine this coordinated control of gene expression in the context of additional transcription factors within the transcriptional network that programs CD8(+) effector and memory T cell differentiation.

  16. Optical interactions of aircraft windscreens and HUDs (Head-Up Displays) producing diplopia

    Science.gov (United States)

    Genco, L. V.

    1983-12-01

    The Air Force is in the process of evaluating new, wide field of view heads-up displays (WFOV HUDs) capable of presenting an enhanced array of visual imagery to pilots of modern aircraft. The main findings of this study are: (1) observers are relatively intolerant of negative disparity, (2) longer viewing is more likely to lead to a diplopia effect than very short glances, (3) resistance to disparity appears to be an individual trait, and (4) a large proportion of responses involve suppression of the view from one eye. The overall median negative disparity threshold was 1.2 mrad and the overall positive threshold was 2.6 mrad. These values are recommended as the maximum disparities acceptable for wide-field-of-view Canopy-HUD optical systems. Since the values are so small, we further recommend that the canopy and HUD be treated as a system, with technical interaction between the vendors, and between the vendors and the USAF. The disparity values indicate the net difference between both system components, so optimization may be possible by appropriately matching the optics.

  17. DOE-HUD initiative on energy efficiency in housing: A federal partnership

    Energy Technology Data Exchange (ETDEWEB)

    Brinch, J. [Energetics, Inc., Columbia, MD (United States); Ternes, M. [Oak Ridge National Lab., TN (United States); Myers, M. [USDOE, Washington, DC (United States)

    1996-07-01

    A five-year initiative between the US Department of Energy (DOE) and the US Department of Housing and Urban Development (HUD) demonstrated the feasibility of improving the energy efficiency of publicly-assisted housing. Twenty-seven projects and activities undertaken during 1990--95 involved research and field demonstrations, institutional and administrative changes to HUD policies and procedures, innovative financing and leveraging of federal dollars with non-federal money, and education, training, and technical assistance. With most of the 27 projects and activities completed, the two departments have initiated a five-year deployment effort, the DOE-Energy Partnerships for Affordable Homes, to achieve energy and water savings in public and assisted housing on a large scale throughout the country. A Clearinghouse for Energy Efficiency in Public and Assisted Housing managed by the National Center for Appropriate Technology (NCAT), will offer hands-on energy assistance to housing providers to complement DOE`s assistance. This paper presents the findings of the DOE-HUD Initiative, with primary attention paid to those projects which successfully integrated energy efficiency into private and public single and multifamily housing. The paper includes examples of the publications, case-study reports, exhibits and videotapes developed during the course of the Initiative. Information on the new DOE Energy Partnerships and on the NCAT Clearinghouse is also presented. New Partnership projects with the Atlanta and Chicago Housing Authorities describe the technical assistance envisioned under the Partnership.

  18. Analysis list: ID1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ID1 Digestive tract + hg19 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/ID...1.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/ID1.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/ID...1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/ID1.Digestive_tract.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/Digestive_tract.gml ...

  19. Id transcriptional regulators in adipogenesis and adipose tissue metabolism.

    Science.gov (United States)

    Patil, Mallikarjun; Sharma, Bal Krishan; Satyanarayana, Ande

    2014-06-01

    Id proteins (Id1-Id4) are helix-loop-helix (HLH) transcriptional regulators that lack a basic DNA binding domain. They act as negative regulators of basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibit their DNA binding and transcriptional activity. Id proteins are implicated in the regulation of various cellular mechanisms such as cell proliferation, cellular differentiation, cell fate determination, angiogenesis and tumorigenesis. A handful of recent studies also disclosed that Id proteins have critical functions in adipocyte differentiation and adipose tissue metabolism. Here, we reviewed the progress made thus far in understanding the specific functions of Id proteins in adipose tissue differentiation and metabolism. In addition to reviewing the known mechanisms of action, we also discuss possible additional mechanisms in which Id proteins might participate in regulating adipogenic and metabolic pathways.

  20. To ID or Not to ID? Changes in Classification Rates of Intellectual Disability Using "DSM-5"

    Science.gov (United States)

    Papazoglou, Aimilia; Jacobson, Lisa A.; McCabe, Marie; Kaufmann, Walter; Zabel, T. Andrew

    2014-01-01

    The "Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition" ("DSM-5") diagnostic criteria for intellectual disability (ID) include a change to the definition of adaptive impairment. New criteria require impairment in one adaptive domain rather than two or more skill areas. The authors examined the diagnostic…

  1. Low Physical Fitness Levels in Older Adults with ID: Results of the HA-ID Study

    Science.gov (United States)

    Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2012-01-01

    Physical fitness is as important to aging adults with ID as in the general population, but to date, the physical fitness levels of this group are unknown. Comfortable walking speed, muscle strength (grip strength), muscle endurance (30 s Chair stand) and cardiorespiratory endurance (10 m incremental shuttle walking test) were tested in a sample of…

  2. Low Physical Fitness Levels in Older Adults with ID: Results of the HA-ID Study

    Science.gov (United States)

    Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2012-01-01

    Physical fitness is as important to aging adults with ID as in the general population, but to date, the physical fitness levels of this group are unknown. Comfortable walking speed, muscle strength (grip strength), muscle endurance (30 s Chair stand) and cardiorespiratory endurance (10 m incremental shuttle walking test) were tested in a sample of…

  3. To ID or Not to ID? Changes in Classification Rates of Intellectual Disability Using "DSM-5"

    Science.gov (United States)

    Papazoglou, Aimilia; Jacobson, Lisa A.; McCabe, Marie; Kaufmann, Walter; Zabel, T. Andrew

    2014-01-01

    The "Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition" ("DSM-5") diagnostic criteria for intellectual disability (ID) include a change to the definition of adaptive impairment. New criteria require impairment in one adaptive domain rather than two or more skill areas. The authors examined the diagnostic…

  4. DriveID: safety innovation through individuation.

    Science.gov (United States)

    Sawyer, Ben; Teo, Grace; Mouloua, Mustapha

    2012-01-01

    The driving task is highly complex and places considerable perceptual, physical and cognitive demands on the driver. As driving is fundamentally an information processing activity, distracted or impaired drivers have diminished safety margins compared with non- distracted drivers (Hancock and Parasuraman, 1992; TRB 1998 a & b). This competition for sensory and decision making capacities can lead to failures that cost lives. Some groups, teens and elderly drivers for example, have patterns of systematically poor perceptual, physical and cognitive performance while driving. Although there are technologies developed to aid these different drivers, these systems are often misused and underutilized. The DriveID project aims to design and develop a passive, automated face identification system capable of robustly identifying the driver of the vehicle, retrieve a stored profile, and intelligently prescribing specific accident prevention systems and driving environment customizations.

  5. Id2 deletion attenuates Apc-deficient ileal tumor formation

    Directory of Open Access Journals (Sweden)

    Kyoko Biyajima

    2015-08-01

    Full Text Available The expression level of inhibitor of DNA binding 2 (Id2 is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promotes ileal tumor initiation in Apc-deficient mice. Expression of Id2 was stimulated by Wnt signaling through the enhancer region of the Id2 promoter at the early stage of tumorigenesis in Apc+/Δ716 (ApcΔ716 mice. Genetic depletion of Id2 in ApcΔ716 mice caused ∼80% reduction in the number of ileal polyps, but had little effect on tumor size. Notably, the lack of Id2 increased the number of apoptotic cells in the normal crypt epithelium of the mice. Furthermore, DNA microarray analysis revealed that the expression level of Max dimerization protein 1 (Mxd1, known as a c-Myc antagonist, was specifically increased by Id2 deletion in the ileal intestinal epithelium of ApcΔ716 mice. In contrast, the protein level of c-Myc, but not the mRNA level, was decreased by loss of Id2 in these mice. These results indicate that loss of Id2 inhibits tumor initiation by up-regulation of Mxd1 and down-regulation of c-Myc in ApcΔ716 mice.

  6. How do frequent users of crisis helplines differ from other users regarding their reasons for calling? Results from a survey with callers to Lifeline, Australia's national crisis helpline service.

    Science.gov (United States)

    Middleton, Aves; Woodward, Alan; Gunn, Jane; Bassilios, Bridget; Pirkis, Jane

    2017-05-01

    Crisis helplines are designed to provide short-term support to people in an immediate crisis. However, there is a group of users who call crisis helplines frequently over an extended period of time. The reasons for their ongoing use remain unclear. The aim of this study was to investigate the differences in the reasons for calling between frequent and other users of crisis helplines. This was achieved by examining the findings from a brief survey completed by callers to Lifeline Australia at the end of their call between February and July 2015. In the survey, callers reported on their socio-demographics, reasons for their current call and number of calls made in the past month. Survey respondents were categorised as frequent, episodic and one-off users, and analyses were conducted using ordered logistic regression. Three hundred and fifteen callers completed the survey, which represented 57% of eligible callers. Twenty-two per cent reported calling 20 times or more in the past month (frequent users), 51% reported calling between 2 and 19 times (episodic users) and 25% reported calling once (one-off users). Two per cent were unable to recall the number of calls they made in the past month. Frequent users reported similar reasons for calling as other users but they were more likely to call regularly to talk about their feelings [OR = 6.0; 95% CI: 3.7-9.8]. This pattern of service use is at odds with the current model of care offered by crisis helplines which is designed to provide one-off support. There is a need to investigate further the factors that drive frequent users to call crisis helplines regularly. © 2016 John Wiley & Sons Ltd.

  7. Osmanlı Tekke Mutfak Kültürü ve Mecmuâ-i Fevâid / The Ottoman Dervish Lodge Cuisine and Majmūʿa al-fawāʾid

    Directory of Open Access Journals (Sweden)

    Güldane

    2016-12-01

    Full Text Available The dervish lodge cuisine in the Ottoman lodge structuring has a central importance. The lodge cuisine helped Anatolia turn into a homeland. Travelers took shelter in the lodges in Anatolia. So, these buildings were a safe haven for those who travel. Lodge’s kitchens were always open. These kitchens offered a delightful “Sheikh Baba’s Soup” anytime and these kitchens gave peace and serenity to Anatolia. This article analyzes the Ottoman lodge food culture in the context of a manuscript which belongs to an imaret. This manuscript called Majmūʿa al-fawāʾid was written in between 1240-1250 (1825-1835 in Istanbul. This work belongs to the period of Sultan Mahmud II and the Hudāyī Lodge Foundation. Institution Employees and accounting records were disclosed in this manuscript in which the names of kitchenware are mentioned and recipes are found. This work gives detailed information about foods that are cooked in the Hudāyī Lodge Foundation’s imaret kitchen. SUMMARY Eating is thought always to be important and it is considered worthwhile to eat with guests and travelers in Turkish culture. In the process of Islamization, the dining table was accepted “Halil İbrahim’s Table” and this approach has strengthened further the hospitality. Eating with people, preparing the table for the guests, travelers and the needy were regarded as a factor increasing the fertility of the table. In addition, these movements were considered an act of social cooperation and deepen the collective consciousness. Especially the sufis played a dominant role in the process of Islamization in Anatolia and depending on this, they undertook various social and cultural functions that including catering. In this regard, the lodge was seen as a complex and this structure encompasses different units such as imaret or soup kitchen, mosque, tomb, library, dervish cells, public fountains, bakery and bathhouse. Travelers stay in the imaret and supply their needs

  8. Memristor Crossbar-based Hardware Implementation of IDS Method

    OpenAIRE

    Merrikh-Bayat, Farnood; Bagheri-Shouraki, Saeed; Rohani, Ali

    2010-01-01

    Ink Drop Spread (IDS) is the engine of Active Learning Method (ALM), which is the methodology of soft computing. IDS, as a pattern-based processing unit, extracts useful information from a system subjected to modeling. In spite of its excellent potential in solving problems such as classification and modeling compared to other soft computing tools, finding its simple and fast hardware implementation is still a challenge. This paper describes a new hardware implementation of IDS method based o...

  9. Commissioning of the IDS Neutron Detector and $\\beta$-decay fast-timing studies at IDS

    CERN Document Server

    Piersa, Monika

    2016-01-01

    The following report describes my scientific activities performed during the Summer Student Programme at ISOLDE. The main part of my project was focused on commissioning the neutron detector dedicated to nuclear decay studies at ISOLDE Decay Station (IDS). I have participated in all the steps needed to make it operational for the IS609 experiment. In the testing phase, we obtained expected detector response and calibrations confirmed its successful commissioning. The detector was mounted in the desired geometry at IDS and used in measurements of the beta-delayed neutron emission of $^8$He. After completing aforementioned part of my project, I became familiar with the fast-timing method. This technique was applied at IDS in the IS610 experiment performed in June 2016 to explore the structure of neutron-rich $^{130-134}$Sn nuclei. Since the main part of my PhD studies will be the analysis of data collected in this experiment, the second part of my project was dedicated to acquiring knowledge about technical de...

  10. Ecological review of black-grass (Alopecurus myosuroides Huds. propagation abilities in relationship with herbicide resistance

    Directory of Open Access Journals (Sweden)

    Maréchal, PY.

    2012-01-01

    Full Text Available Alopecurus myosuroides Huds. (black-grass has always been a major concern for cereal growers, and the development of herbicide resistance does not improve the situation. This review article summarizes the different traits involved in the dispersal pattern of herbicide resistant black-grass individuals within a susceptible field population. Therefore, the whole life cycle of black-grass is depicted from the seed to the seed. From the early vegetative development to the seed falling, every stage is described, taking into account how herbicide resistance can influence or exert a different impact compared to susceptible plants.

  11. A Contextual Model for Identity Management (IdM) Interfaces

    Science.gov (United States)

    Fuller, Nathaniel J.

    2014-01-01

    The usability of Identity Management (IdM) systems is highly dependent upon design that simplifies the processes of identification, authentication, and authorization. Recent findings reveal two critical problems that degrade IdM usability: (1) unfeasible techniques for managing various digital identifiers, and (2) ambiguous security interfaces.…

  12. Evaluation of the chromogenic agar chromID C. difficile.

    Science.gov (United States)

    Eckert, Catherine; Burghoffer, Béatrice; Lalande, Valérie; Barbut, Frederic

    2013-03-01

    Three selective media (chromID C. difficile agar, taurocholate cycloserine cefoxitin agar [TCCA; homemade], and CLO medium) were compared from 406 stool samples of patients suspected of having Clostridium difficile infection. The sensitivities of chromID C. difficile agar at 24 h and 48 h, CLO medium, and TCCA were 74.1%, 87%, 85.2%, and 70.4%, respectively.

  13. Evaluation of the Chromogenic Agar chromID C. difficile

    OpenAIRE

    2013-01-01

    Three selective media (chromID C. difficile agar, taurocholate cycloserine cefoxitin agar [TCCA; homemade], and CLO medium) were compared from 406 stool samples of patients suspected of having Clostridium difficile infection. The sensitivities of chromID C. difficile agar at 24 h and 48 h, CLO medium, and TCCA were 74.1%, 87%, 85.2%, and 70.4%, respectively.

  14. ID Model Construction and Validation: A Multiple Intelligences Case

    Science.gov (United States)

    Tracey, Monica W.; Richey, Rita C.

    2007-01-01

    This is a report of a developmental research study that aimed to construct and validate an instructional design (ID) model that incorporates the theory and practice of multiple intelligences (MI). The study consisted of three phases. In phase one, the theoretical foundations of multiple Intelligences and ID were examined to guide the development…

  15. Evaluation of ID-PaGIA syphilis antibody test.

    Science.gov (United States)

    Naaber, Paul; Makoid, Ene; Aus, Anneli; Loivukene, Krista; Poder, Airi

    2009-01-01

    Laboratory diagnosis of syphilis is usually accomplished by serology. There are currently a large number of different commercial treponemal tests available that vary in format, sensitivity and specificity. To evaluate the ID-PaGIA Syphilis Antibody Test as an alternative to other specific treponemal tests for primary screening or confirmation of diagnosis. Serum samples from healthy adults (n = 100) were used for detection of specificity of ID-PaGIA. To evaluate sensitivity of ID-PaGIA serum samples (n = 101) from patients with confirmed or suspected syphilis were tested for syphilis antibodies with FTA-Abs IgM, ID-PaGIA, ELISA IgM and TPHA tests. No false-positive results were found with ID-PaGIA. Sensitivity of various treponemal tests was the following: FTA-Abs IgM: 95.5%, ID-PaGIA and ELISA IgM: 94%, and TPHA 75%. The positive and negative predictive values of ID-PaGIA were 100 and 89.5%, respectively. Compared with other treponemal tests ID-PaGIA has excellent sensitivity and specificity.

  16. The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site

    DEFF Research Database (Denmark)

    Babakhanyan, Anna; Leke, Rose G F; Salanti, Ali;

    2014-01-01

    antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired...... cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a....

  17. Extending and implementing the Persistent ID pillars

    Science.gov (United States)

    Car, Nicholas; Golodoniuc, Pavel; Klump, Jens

    2017-04-01

    The recent double decade anniversary of scholarly persistent identifier use has triggered journal special editions such as "20 Years of Persistent Identifiers". For such a publication, it is apt to consider the longevity of some persistent identifier (PID) mechanisms (Digital Object Identifiers) and the partial disappearance of others (Life Sciences IDs). We have previously postulated a set of "PID Pillars" [1] which are design principles aimed at ensuring PIDs can survive technology and social change and thus persist for the long term that we have drawn from our observations of PIDs at work over many years. The principles: describe how to ensure identifiers' system and organisation independence; codify the delivery of essential PID system functions; mandate a separation of PID functions from data delivery mechanisms; and require generation of policies detailing how change is handled. In this presentation, first we extend on our previous work of introducing the pillars by refining their descriptions, giving specific suggestions for each and presenting some work that addresses them. Second, we propose a baseline data model for persistent identifiers that, if used, would assist the separation of PID metadata and PID system functioning. This would allow PID system function specifics to change over time (e.g. resolver services or even resolution protocols) and yet preserve the PIDs themselves. Third, we detail our existing PID system — the PID Service [2] — that partially implements the pillars and describe both its successes and shortcomings. Finally, we describe our planned next-generation system that will aim to use the baseline data model and fully implement the pillars.

  18. Classification of artificial intelligence ids for smurf attack

    CERN Document Server

    Ugtakhbayar, N; Sodbileg, Sh

    2012-01-01

    Many methods have been developed to secure the network infrastructure and communication over the Internet. Intrusion detection is a relatively new addition to such techniques. Intrusion detection systems (IDS) are used to find out if someone has intrusion into or is trying to get it the network. One big problem is amount of Intrusion which is increasing day by day. We need to know about network attack information using IDS, then analysing the effect. Due to the nature of IDSs which are solely signature based, every new intrusion cannot be detected; so it is important to introduce artificial intelligence (AI) methods / techniques in IDS. Introduction of AI necessitates the importance of normalization in intrusions. This work is focused on classification of AI based IDS techniques which will help better design intrusion detection systems in the future. We have also proposed a support vector machine for IDS to detect Smurf attack with much reliable accuracy.

  19. Expression of Id2 in the Second Heart Field and Cardiac Defects in Id2 Knock-Out Mice

    NARCIS (Netherlands)

    Jongbloed, M. R. M.; Vicente-Steijn, R.; Douglas, Y. L.; Wisse, L. J.; Mori, K.; Yokota, Y.; Bartelings, M. M.; Schalij, M. J.; Mahtab, E. A.; Poelmann, R. E.; Gittenberger-De Groot, A. C.

    2011-01-01

    The inhibitor of differentiation Id2 is expressed in mesoderm of the second heart field, which contributes myocardial and mesenchymal cells to the primary heart tube. The role of Id2 in cardiac development is insufficiently known. Heart development was studied in sequential developmental stages in I

  20. Idéologie : le mot, l’idée, la chose.

    Directory of Open Access Journals (Sweden)

    Pierre Macherey

    2008-04-01

    Full Text Available L’article examine les conditions dans lesquelles le néologisme « idéologie », entre 1796, date à laquelle il a été forgé par Destutt de Tracy, et 1845, date à laquelle il a été réutilisé par Marx, est passé d’une valeur positive (en tant que science générale des idées à une valeur connotée négativement (en tant que système social de croyances décalé par rapport à la réalité qu’il évoque.« Ideology : the word, the idea, the thing ». This paper studies the transvaluation of “ideology” as a neologism. Between 1796 (when the notion of “ideology” was invented by Destutt de Tracy and 1845 (when it was reused by Marx, “ideology” changed its positive value (it refers to a general science of ideas into a negative one (because it was referred to a social system of believes, shifted from the reality it mentions.

  1. Biometric authentication for ID cards with hologram watermarks

    Science.gov (United States)

    Croce Ferri, Lucilla; Mayerhoefer, Astrid; Frank, Marcus; Vielhauer, Claus; Steinmetz, Ralf

    2002-04-01

    We present an analysis of a new technique for the authentication of ID cardholders, based on the integration of a biometrics-based authentication system with digital watermarks. The chosen biometric authentication method is the dynamic signature verification of the ID cardholder, while we use a specific integrity watermark technique we developed, called Hologram Watermark, to embed and retrieve the off-line data onto an ID card. We take advantage of the fact, that two static biometric features (images of the user's face and signature) are already integral part of ID cards for manual verification and extent the stored biometric information by embedding on-line handwriting features of the signature as holographic watermarks in the overall image information of an ID card. Manipulation of any of the image information can be detected and will further disallow biometric verification of the forger. The Hologram Watermark technique produces content-related data using computer-generated hologram coding techniques. These data are embedded with watermarking techniques into the personal data printed on an ID card. The content-related data in this specific application are the dynamic features of the cardholder's signature. The main goal of this paper is to analyze the suitability of dynamic signature verification in combination with the Hologram Watermark technique, to facilitate automated user authentication based on information transparently embedded in ID cards.

  2. 78 FR 57873 - 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

    Science.gov (United States)

    2013-09-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 60-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales...-Owned Real Estate--Sales Contract and Addendums. OMB Approval Number: 2502-0306. Type of Request (i.e...

  3. HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.

    Directory of Open Access Journals (Sweden)

    Filip Vanevski

    Full Text Available Highly specific activity-dependent neuronal responses are necessary for modulating synapses to facilitate learning and memory. We present evidence linking a number of important processes involved in regulating synaptic plasticity, suggesting a mechanistic pathway whereby activity-dependent signaling, likely through protein kinase C (PKC-mediated phosphorylation of HuD, can relieve basal repression of Bdnf mRNA translation in dendrites, allowing for increased TrkB signaling and synaptic remodeling. We demonstrate that the neuronal ELAV family of RNA binding proteins associates in vivo with several Bdnf mRNA isoforms present in the adult brain in an activity-dependent manner, and that one member, HuD, interacts directly with sequences in the long Bdnf 3' untranslated region (3'UTR and co-localizes with Bdnf mRNA in dendrites of hippocampal neurons. Activation of PKC leads to increased dendritic translation of mRNAs containing the long Bdnf 3'UTR, a process that is dependent on the presence of HuD and its phosphorylation at threonine residues 149 and/or 165. Thus, we found a direct effect of HuD on regulating translation of dendritic Bdnf mRNAs to mediate local and activity-dependent increases in dendritic BDNF synthesis.

  4. 76 FR 35461 - Notice of Web Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2011...

    Science.gov (United States)

    2011-06-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND... Year (FY) 2011 Capacity Building for Sustainable Communities Program AGENCY: Office of the Chief of the... HUD's FY2011 Capacity Building for Sustainable Communities Program NOFA. Specifically, this NOFA...

  5. 77 FR 30546 - Notice of Proposed Information Collection: Comment Request; Form HUD-40221(rev) “LOCCS/VRS Self...

    Science.gov (United States)

    2012-05-23

    ...) ``LOCCS/VRS Self-Help Homeownership Opportunity Program Payment Voucher'' AGENCY: Office of the Assistant... Payment Voucher'' prior to requesting a drawdown of funds through LOCCS/VRS. Title of Proposal: Form HUD-40221(rev) ``LOCCS/VRS Self-help Homeownership Opportunity Program Payment Voucher''. OMB Control...

  6. 78 FR 79473 - 60 Day Notice of Proposed Information Collection for Public Comment: Reporting for HUD Research...

    Science.gov (United States)

    2013-12-30

    ... URBAN DEVELOPMENT 60 Day Notice of Proposed Information Collection for Public Comment: Reporting for HUD... soliciting public comments on the subject proposal. DATES: Comment Due Date: February 28, 2014. ADDRESSES... hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay...

  7. 75 FR 54900 - Notice of HUD-Held Multifamily and Healthcare Loan Sale (MHLS 2010-2)

    Science.gov (United States)

    2010-09-09

    ... mortgage loans. SUMMARY: This notice announces HUD's intention to sell certain unsubsidized multifamily and... the opportunity to purchase assets directly from the Department. It is anticipated that any direct... its intention to sell in MHLS 2010-2 certain unsubsidized mortgage loans (Mortgage Loans) secured...

  8. Improved ID-Based Signature Scheme Solving Key Escrow

    Institute of Scientific and Technical Information of China (English)

    LIAO Jian; QI Ying-hao; HUANG Pei-wei; RONG Men-tian; LI Sheng-hong

    2006-01-01

    Key escrow is an inherent disadvantage for traditional ID-based cryptosystem, i.e. , the dishonest private key generator (PKG) can forge the signature of any user, meanwhile, the user can deny the signature actually signed by him/herself. To avoid the keyescrow problem, an ID-based signature scheme was presented without trusted PKG. The exact proof of security was presented to demonstrate that our scheme is secure against existential forgery on adaptively chosen message and ID attacks assuming the complexity of computational Diffie-Hellman(CDH) problem. Compared with other signature schemes, the proposed scheme is more efficient.

  9. Ficaria verna Huds. extracts and their β-cyclodextrin supramolecular systems

    Directory of Open Access Journals (Sweden)

    Hădărugă Nicoleta G

    2012-03-01

    Full Text Available Abstract Background Obtaining new pharmaceutical materials with enhanced properties by using natural compounds and environment-friendly methods is a continuous goal for scientists. Ficaria verna Huds. is a widespread perennial plant with applications in the treat of haemorrhoids and to cure piles; it has also anti-inflammatory, astringent, and antibiotic properties. The goal of the present study is the obtaining and characterization of new F. verna extract/β-cyclodextrin complexes by using only natural compounds, solvents, and environment-friendly methods in order to increase the quality and acceptability versus toxicity indicator. Thus, the flavonoid content (as quercetin of Ficaria verna Huds. flowers and leaves from the West side of Romania was determined and correlated with their antioxidant activity. Further, the possibility of obtaining β-cyclodextrin supramolecular systems was studied. Results F. verna flowers and leaves extracts were obtained by semi-continuous solid-liquid extraction. The raw concentrated extract was spectrophotometrically analyzed in order to quantify the flavonoids from plant parts and to evaluate the antioxidant activity of these extracts. The F. verna extracts were used for obtaining β-cyclodextrin complexes; these were analyzed by scanning electron microscopy and Karl Fischer water titration; spectrophotometry was used in order to quantifying the flavonoids and evaluates the antioxidant activity. A higher concentration of flavonoids of 0.5% was determined in complexes obtained by crystallisation method, while only a half of this value was calculated for kneading method. The antioxidant activity of these complexes was correlated with the flavonoid content and this parameter reveals possible controlled release properties. Conclusions The flavonoid content of F. verna Huds. from the West side of Romania (Banat county is approximately the same in flowers and leaves, being situated at a medium value among other

  10. RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1.

    Science.gov (United States)

    Kim, Chongtae; Lee, Heejin; Kang, Hoin; Shin, Jung Jae; Tak, Hyosun; Kim, Wook; Gorospe, Myriam; Lee, Eun Kyung

    2016-04-01

    Although triglyceride (TG) accumulation in the pancreas leads to β-cell dysfunction and raises the chance to develop metabolic disorders such as type 2 diabetes (T2DM), the molecular mechanisms whereby intracellular TG levels are regulated in pancreatic β cells have not been fully elucidated. Here, we present evidence that the RNA-binding protein HuD regulates TG production in pancreatic β cells. Mouse insulinoma βTC6 cells stably expressing a small hairpin RNA targeting HuD (shHuD) (βTC6-shHuD) contained higher TG levels compared to control cells. Moreover, downregulation of HuD resulted in a decrease in insulin-induced gene 1 (INSIG1) levels but not in the levels of sterol regulatory element-binding protein 1c (SREBP1c), a key transcription factor for lipid production. We identified Insig1 mRNA as a direct target of HuD by using ribonucleoprotein immunoprecipitation (RIP) and biotin pulldown analyses. By associating with the 3'-untranslated region (3'UTR) of Insig1 mRNA, HuD promoted INSIG1 translation; accordingly, HuD downregulation reduced while ectopic HuD expression increased INSIG1 levels. We further observed that HuD downregulation facilitated the nuclear localization of SREBP1c, thereby increasing the transcriptional activity of SREBP1c and the expression of target genes involved in lipogenesis; likewise, we observed lower INSIG1 levels in the pancreatic islets of HuD-null mice. Taken together, our results indicate that HuD functions as a novel repressor of lipid synthesis in pancreatic β cells.

  11. Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Desprez, Pierre-Yves; Campisi, Judith

    2014-09-30

    A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a delivery vehicle comprising a product which modulates Id-1 or Id-2 expression.

  12. Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    Science.gov (United States)

    Desprez, Pierre-Yves; Campisi, Judith

    2014-09-30

    A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a delivery vehicle comprising a product which modulates Id-1 or Id-2 expression.

  13. Lowest-ID with Adaptive ID Reassignment: A Novel Mobile Ad-Hoc Networks Clustering Algorithm

    CERN Document Server

    Gavalas, Damianos; Konstantopoulos, Charalampos; Mamalis, Basilis

    2011-01-01

    Clustering is a promising approach for building hierarchies and simplifying the routing process in mobile ad-hoc network environments. The main objective of clustering is to identify suitable node representatives, i.e. cluster heads (CHs), to store routing and topology information and maximize clusters stability. Traditional clustering algorithms suggest CH election exclusively based on node IDs or location information and involve frequent broadcasting of control packets, even when network topology remains unchanged. More recent works take into account additional metrics (such as energy and mobility) and optimize initial clustering. However, in many situations (e.g. in relatively static topologies) re-clustering procedure is hardly ever invoked; hence initially elected CHs soon reach battery exhaustion. Herein, we introduce an efficient distributed clustering algorithm that uses both mobility and energy metrics to provide stable cluster formations. CHs are initially elected based on the time and cost-efficien...

  14. Related factors of attempted suicide among Beijing psychological aids hotline callers%北京心理援助热线来电者自杀未遂的相关因素

    Institute of Scientific and Technical Information of China (English)

    庞宇; 杨甫德; 童永胜; 赵丽婷; 王翠玲; 梁红; 李献云; 安静

    2015-01-01

    Objectives:To explore the prevalence and correlates of attempted suicide among Beijing psycho-logical aids hotline callers,in order to provide knowledge of hotline-based suicide prevention.Methods:From De-cember 2002 to December 2008,all the effective callers who consulted themselves'psychological problem,by Bei-jing psychological aids hotline were interviewed by professional hotline operators during the consulting calling.Data of whether callers attempted suicidal behavior in 2 weeks prior to the calling,gender and other 5 demographic char-acteristics of callers were collected via hotline interview.A questionnaire including depression screening scale,com-mon psychiatric symptoms such as delusion,hallucination,etc.,a history of substance abuse or dependence,a histo-ry of suicidal behavior,having had acute or chronic life events,and severity of hopeless was used during hotline in-terview.Logistic regression model was used.Results:In 22 415 interviewed callers,362 (1.6%)callers (233 fe-males)reported that they attempted suicidal behavior in 2 weeks prior to the calling.After adjusted for demographic characteristics,prior suicidal behavior 2 weeks before calling (OR=4.43,95%CI:3.37-5.83),hopelessness (OR=2.01,95%CI:1.52-2.67),substance abuse (OR=1.97,95%CI:1.48 -2.62),acute negative life events (OR=1.94,95%CI:1.49-2.52),and severe depressive symptoms (OR=1.45,95%CI:1.08-1.95)were associatedwith attempted suicide among hotline callers.Conclusion:The rates of attempted suicide among hotline callers are probably high.Suicide prevention in hotline would shed light on improving coping skills for life events and sub-stance abuse problems for hotline callers.%目的:探讨心理援助热线来电者自杀未遂行为的发生情况及其相关因素,为制定自杀热线干预措施提供依据。方法:北京市心理援助热线接线员在2002-2008年接听全部有效来电时,询问来电者在2周内是否实施过自杀行为,使用抑郁症诊断筛查

  15. Role of yeast domination in Indian idli batter fermentation.

    Science.gov (United States)

    Soni, S K; Sandhu, D K

    1991-07-01

    Adding Saccharomyces cerevisiae, along with natural bacterial flora of the ingredients, was the best method for standardizing idli termentation in terms of improved organoleptic characteristics, leavening and nutritional constituents.

  16. Defining the safe current limit for opening ID photon shutter

    Energy Technology Data Exchange (ETDEWEB)

    Seletskiy, S. [Brookhaven National Lab. (BNL), Upton, NY (United States). Photon Sciences Dept.

    2015-12-14

    The NSLS-II storage ring is protected from possible damage from insertion devices (IDs) synchrotron radiation by a dedicated active interlock system (AIS). It monitors electron beam position and angle and triggers beam drop if beam orbit exceeds the boundaries of pre-calculated active interlock envelope (AIE). The beamlines (BL) and beamline frontends (FE) are designed under assumption that the electron beam is interlocked within the AIE. For historic reasons the AIS engages the ID active interlock (AI-ID) at any non-zero beam current whenever the ID photon shutter (IDPS) is getting opened. Such arrangement creates major inconveniences for BLs commissioning. Apparently there is some IDPS safe current limit (SCL) under which the IDPS can be opened without interlocking the e-beam. The goal of this paper is to find such limit.

  17. Scientists ID Key Fetal Cells Vulnerable to Zika

    Science.gov (United States)

    ... html Scientists ID Key Fetal Cells Vulnerable to Zika Lab study suggests possible mechanism for birth defects ... 29, 2016 (HealthDay News) -- The devastating mosquito-borne Zika virus can infect cells that play a role ...

  18. A Good IDS Response Protocol of MANET Containment Strategies

    Science.gov (United States)

    Cheng, Bo-Chao; Chen, Huan; Tseng, Ryh-Yuh

    Much recent research concentrates on designing an Intrusion Detection System (IDS) to detect the misbehaviors of the malicious node in MANET with ad-hoc and mobility natures. However, without rapid and appropriate IDS response mechanisms performing follow-up management services, even the best IDS cannot achieve the desired primary goal of the incident response. A competent containment strategy is needed to limit the extent of an attack in the Incident Response Life Cycle. Inspired by the T-cell mechanisms in the human immune system, we propose an efficient MANET IDS response protocol (T-SecAODV) that can rapidly and accurately disseminate alerts of the malicious node attacks to other nodes so as to modify their AODV routing tables to isolate the malicious nodes. Simulations are conducted by the network simulator (Qualnet), and the experiment results indicate that T-SecAODV is able to spread alerts steadily while greatly reduce faulty rumors under simultaneous multiple malicious node attacks.

  19. Genetics Experts Unite to I.D. Unknown Katrina Victims

    Science.gov (United States)

    ... Current Issue Past Issues Research News From NIH Genetics Experts Unite to I.D. Unknown Katrina Victims ... in the recent Advances in molecular biology and genetics," says team member Stephen Sherry, Ph.D., of ...

  20. FDIC Institution Directory (ID) -- Insured Insitution Download File

    Data.gov (United States)

    Federal Deposit Insurance Corporation — The FDIC's Institution Directory (ID) download file provides a list of all FDIC-insured institutions. The file includes demographic information related to the...

  1. idSpace: Supporting Designers to develop Innovative Products

    NARCIS (Netherlands)

    Sloep, Peter; Bitter-Rijpkema, Marlies; Retalis, Symeon; Georgiakakis, Petros; Dolog, Peter

    2009-01-01

    Sloep, P., Bitter-Rijpkema, M., Retalis, S., Georgiakakis, P., & Dolog, P. (2008). idSpace: Supporting Designers to develop Innovative Products. Presentation at Online Educa. December, 3, 2008. Berlin, Germany.

  2. Security analysis for biometric data in ID documents

    Science.gov (United States)

    Schimke, Sascha; Kiltz, Stefan; Vielhauer, Claus; Kalker, Ton

    2005-03-01

    In this paper we analyze chances and challenges with respect to the security of using biometrics in ID documents. We identify goals for ID documents, set by national and international authorities, and discuss the degree of security, which is obtainable with the inclusion of biometric into documents like passports. Starting from classical techniques for manual authentication of ID card holders, we expand our view towards automatic methods based on biometrics. We do so by reviewing different human biometric attributes by modality, as well as by discussing possible techniques for storing and handling the particular biometric data on the document. Further, we explore possible vulnerabilities of potential biometric passport systems. Based on the findings of that discussion we will expand upon two exemplary approaches for including digital biometric data in the context of ID documents and present potential risks attack scenarios along with technical aspects such as capacity and robustness.

  3. Study IDs 2 Zika Virus Proteins Linked to Microcephaly

    Science.gov (United States)

    ... gov/news/fullstory_160386.html Study IDs 2 Zika Virus Proteins Linked to Microcephaly Discovery might one day ... say they've identified two proteins in the Zika virus linked to the severe birth defect microcephaly. Babies ...

  4. Narva Aleksandri kirikusse paigaldatakse vitraažid / Irina Tokareva

    Index Scriptorium Estoniae

    Tokareva, Irina

    2004-01-01

    1919.a. hävinud vitraažid asendatakse Dolores Hoffmanni originaalsete piiblipersoone kujutavate vitraažidega. Kasutatakse uudset tehnoloogiat. vitraaže on kiriku kaheksa akna jaoks. Villu Jürjo kommentaarid

  5. RadNet Air Data From Idaho Falls, ID

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Idaho Falls, ID from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  6. High brightness MEMS mirror based head-up display (HUD) modules with wireless data streaming capability

    Science.gov (United States)

    Milanovic, Veljko; Kasturi, Abhishek; Hachtel, Volker

    2015-02-01

    A high brightness Head-Up Display (HUD) module was demonstrated with a fast, dual-axis MEMS mirror that displays vector images and text, utilizing its ~8kHz bandwidth on both axes. Two methodologies were evaluated: in one, the mirror steers a laser at wide angles of phone applications is demonstrated, utilizing the mobile device both for content generation based on various messages or data, and for content streaming to the MEMS controller via Bluetooth interface. The display unit is highly resistant to vibrations and shock, and requires only ~1.5W to operate, even with content readable in sunlit outdoor conditions. The low power requirement is in part due to a vector graphics approach, allowing the efficient use of laser power, and also due to the use of a single, relatively high efficiency laser and simple optics.

  7. OCCURRENCE OF ENTOMOPATHOGENIC FUNGI IN SOILS FROM FESTUCA PRATENSIS HUDS. CROP

    Directory of Open Access Journals (Sweden)

    Roman Kolczarek

    2014-04-01

    Full Text Available Entomopathogenic fungi are the largest group of microorganisms existing in the soil environment. Occurrence and pathogenicity of entomopathogenic fungi in soil is dependent on many factors affecting the soil environment. The aim of this study was to compare the species composition and the intensity of the occurrence of entomopathogenic fungi in soils from monoculture crops of Festuca pratensis Huds. The study material consisted of soil samples taken from the experiment conducted in two experimental stations of the Research Centre for Cultivars Study. The insecticides fungi were isolated from soil using a method of the selective substrate. Three species of entomopathogenic fungi Beauveria bassiana, Isaria fumosorosea and Metarhizium anisopliae were isolated from the study soils using the selective medium.

  8. Biometrics and ID Cards — Enablers for Personal Security

    Science.gov (United States)

    Reisen, Andreas

    The electronic ID card is a modernization and security project of the German Government. On the one hand, the multifunctional card is intended to boost security and the convenience of e-government and e-business applications. On the other hand, the new biometric ID card should allow citizens to use it as a travel document in the Schengen area and for specific destinations outside the European Union also in the future.

  9. [Phenolic compounds in leaves insertions of Mentha × villosa Huds. cv. Snežná].

    Science.gov (United States)

    Tekeľová, Daniela; Bittner Fialová, Silvia; Tóth, Jaroslav; Czigle, Szilvia

    Lamiaceae plants mostly accumulate active ingredients in their leaves. The subfamily Nepetoideae, including the genus Mentha L., is characterized by the presence of essential oil and antioxidant phenolics, chiefly hydroxycinnamic acids with predominance of rosmarinic acid, and flavonoids. Mentha × piperita and M. spicata are the most broadly used mints in both medicine and industry, while M. x villosa is less known in our country. Herbal drugs in the form of leaves are usually analysed unpartitioned, while single leaves insertions have only been studied occasionally. Therefore, the aim of this work was the quantification of the active compounds content in the leaves pairs of Mentha × villosa Huds. cv. Snežná, using pharmacopoeial methods: total hydroxycinnamic derivatives expressed as rosmarinic acid (THD) and luteolin-type flavonoids. THD content ranged from 6.7% to 9.4% in the leaves pairs water extracts, and from 6.6% to 14.0% in methanol extracts. Flavonoids contents, expressed as luteolin-7-O-glucoside, ranged from 4.0% to 8.8% in water extracts, and from 4.0% to 10.5% in methanol extracts. Antioxidant activity (DPPH) expressed as SC50 ranged from 10.2 to 16.9 μg.ml-1 (drug dry weight) in water extracts, and from 10.7 to 21.6 μg.ml-1 in methanol extracts. The highest content of phenolic compounds as well as the highest antioxidant activity were found to be in the top sheet, while the lowest content of phenolic compounds and lowest antioxidant activity were detected in the leaves of the middle stem part.Key words: Mentha × villosa Huds cv. Snežná hydroxycinnamic derivatives rosmarinic acid luteolin-7-O-glucoside DPPH.

  10. Accelerated fermentation of 'idli' batter using soy residue okara.

    Science.gov (United States)

    Rekha, C R; Vijayalakshmi, G

    2011-06-01

    The aim of this work was to reduce the natural fermentation period of 'idli' from the conventional 14 h to 10 h by adding underutilized okara for the preparation of 'idli'. Black gram was partially substituted with soy residue okara in the ratio of (1:1). After 14 h of natural fermentation, the pH and total acidity of control 'idli' batter was 4.51 and 0.64% and that of okara fortified 'idli' batter was 4.53 and 0.43%, respectively. The amount of CO2 released by the control and okara fortified batter was 19.7% and 33.6% respectively. The viable count of yeast and mold, lactics and mesophilic bacteria in control & okara batter increased with time reaching 9.00 & 10.34, 8.66 & 7.69, and 8.65 & 9.47 log10 cfu/g, respectively at the end of 10 h of natural fermentation. Okara fortified 'idli' was soft and spongy compared to control 'idli' .

  11. BioID Identification of Lamin-Associated Proteins.

    Science.gov (United States)

    Mehus, Aaron A; Anderson, Ruthellen H; Roux, Kyle J

    2016-01-01

    A- and B-type lamins support the nuclear envelope, contribute to heterochromatin organization, and regulate a myriad of nuclear processes. The mechanisms by which lamins function in different cell types and the mechanisms by which lamin mutations cause over a dozen human diseases (laminopathies) remain unclear. The identification of proteins associated with lamins is likely to provide fundamental insight into these mechanisms. BioID (proximity-dependent biotin identification) is a unique and powerful method for identifying protein-protein and proximity-based interactions in living cells. BioID utilizes a mutant biotin ligase from bacteria that is fused to a protein of interest (bait). When expressed in living cells and stimulated with excess biotin, this BioID-fusion protein promiscuously biotinylates directly interacting and vicinal endogenous proteins. Following biotin-affinity capture, the biotinylated proteins can be identified using mass spectrometry. BioID thus enables screening for physiologically relevant protein associations that occur over time in living cells. BioID is applicable to insoluble proteins such as lamins that are often refractory to study by other methods and can identify weak and/or transient interactions. We discuss the use of BioID to elucidate novel lamin-interacting proteins and its applications in a broad range of biological systems, and provide detailed protocols to guide new applications.

  12. Multimodal biometrics for identity documents (MBioID).

    Science.gov (United States)

    Dessimoz, Damien; Richiardi, Jonas; Champod, Christophe; Drygajlo, Andrzej

    2007-04-11

    The MBioID initiative has been set up to address the following germane question: What and how biometric technologies could be deployed in identity documents in the foreseeable future? This research effort proposes to look at current and future practices and systems of establishing and using biometric identity documents (IDs) and evaluate their effectiveness in large-scale developments. The first objective of the MBioID project is to present a review document establishing the current state-of-the-art related to the use of multimodal biometrics in an IDs application. This research report gives the main definitions, properties and the framework of use related to biometrics, an overview of the main standards developed in the biometric industry and standardisation organisations to ensure interoperability, as well as some of the legal framework and the issues associated to biometrics such as privacy and personal data protection. The state-of-the-art in terms of technological development is also summarised for a range of single biometric modalities (2D and 3D face, fingerprint, iris, on-line signature and speech), chosen according to ICAO recommendations and availabilities, and for various multimodal approaches. This paper gives a summary of the main elements of that report. The second objective of the MBioID project is to propose relevant acquisition and evaluation protocols for a large-scale deployment of biometric IDs. Combined with the protocols, a multimodal database will be acquired in a realistic way, in order to be as close as possible to a real biometric IDs deployment. In this paper, the issues and solutions related to the acquisition setup are briefly presented.

  13. Risk factors for suicidal ideation among psychological aids hotline callers%心理援助热线来电者自杀意念的危险因素

    Institute of Scientific and Technical Information of China (English)

    童永胜; 赵丽婷; 王翠玲; 梁红; 李献云; 王绍礼; 杨甫德

    2013-01-01

    Objective To explore risk factors for suicidal ideation among psychological aids hotline callers.Methods From Aug 2004 to Dec 2008,all the effective callers of psychological aids hotline were interviewed by professional hotline operators with a questionnaire including suicidal ideation and 11 potential risk factors based on prior suicide studies in China.Logistic regression analysis was used.Results Among all the 25 362 effective callers who were seeking for psychological aids hotline service,sixty-four percent (16 228) of them were recruited.Eight thousands eight hundreds and forty-four callers reported having suicidal ideation in 2 weeks prior to the identified calling,741 callers reported suicide plan while having suicidal ideation.Females,older than 19 years old,living in the local site less than 6 years,not unmarried,and unemployed callers were more likely reporting suicidal ideation.Having psychiatric symptoms (OR =3.35,95 % CI:2.93-3.82,P < 0.001),hopeless (OR =3.32,95 % CI:3.06-3.60,P < 0.001),prior attempt suicide history (OR =2.21,95% CI:1.99-2.46,P < 0.001),substance abuse (OR =1.42,95%CI:1.26-1.61,P<0.001),serious physical illness (OR =1.34,95%CI:1.20-1.50,P< 0.001),relatives or associates with prior suicide history.(OR =1.33,95% CI:1.23-1.44,P < 0.001),acute life events (OR =1.30,95% CI:1.20-1.40,P < 0.001),and chronic life events (OR =1.23,95% CI:1.14-1.33,P < 0.001) were independent risk fac tors for suicidal ideation among the hotline callers,after sex,age,and the other 4 demographic variables were adjusted.Conclusions Similar with other young population,having psychiatric symptoms,hopeless,and prior attempted suicide history are probably be the most important risk factors for suicidal ideation among hotline callers.%目的 筛选心理援助热线来电者自杀意念的危险因素.方法 北京心理援助热线2004-2008年在接听来电时,接线员使用来电者自杀意念及危险因素调查表询问来电

  14. 76 FR 17582 - Special Conditions: Bombardier Model BD-700-1A10 and BD-700-1A11 Airplanes, Head-Up Display (HUD...

    Science.gov (United States)

    2011-03-30

    ...-1A11 Airplanes, Head-Up Display (HUD) With Video Synthetic Vision System (SVS) AGENCY: Federal Aviation... Certificate Data Sheet (TCDS) T00003NY, those aircraft models are known under the marketing designation of...

  15. 76 FR 17062 - Special Conditions: Bombardier Model BD-700-1A10 and BD-700-1A11 Airplanes, Head-Up Display (HUD...

    Science.gov (United States)

    2011-03-28

    ...-1A11 Airplanes, Head-Up Display (HUD) With Video Synthetic Vision System (SVS) AGENCY: Federal Aviation... Certificate Data Sheet (TCDS) T00003NY, those aircraft models are known under the marketing designation of...

  16. 76 FR 31223 - Special Conditions: Bombardier Model BD-700-1A10 and BD-700-1A11 Airplanes, Head-up Display (HUD...

    Science.gov (United States)

    2011-05-31

    ...-1A11 Airplanes, Head-up Display (HUD) With Video Synthetic Vision System (SVS) AGENCY: Federal Aviation.... Per Type Certificate Data Sheet (TCDS) T00003NY, those aircraft models are known under the marketing...

  17. The Self- and Other-Deception Questionnaires-Intellectual Disabilities (SDQ-ID and ODQ-ID): component analysis and reliability.

    Science.gov (United States)

    Jobson, Laura; Stanbury, Alexandra; Langdon, Peter E

    2013-10-01

    The objectives of this research were to: (1) investigate the component structure and psychometric properties of the Self- and Other-Deception Questionnaires-Intellectual Disabilities (SDQ-ID and ODQ-ID), (2) examine the relationship between social desirability and IQ, and (3) compare social desirability scores of those with intellectual disabilities (IDs) and a history of criminal offending to the social desirability scores of participants with IDs and those without IDs and no such history, controlling for general intellectual functioning. Men with mild to borderline IDs detained within medium secure inpatient forensic mental health services (N=40) completed the SDQ-ID and ODQ-ID at Time 1 and then two-weeks later at Time 2. Data for the men with and without IDs and no known criminal offending history were taken from a previous study (N=60). Following exploratory Principal Components Analysis, the number of questionnaire items were reduced, and a two-factor structure was found for the SDQ-ID which was labelled: (1) Positive Self Representation and (2) Denial of Intrusive Thoughts. A two-factor structure was also found for the ODQ-ID and these two factors were labelled: (1) Denial of Negative Social Interaction and (2) Untrustworthiness. Both the SDQ-ID and ODQ-ID had acceptable internal consistency and test-retest reliability. Fifteen percent of the variance in SDQ-ID scores was explained by Full Scale IQ, while 21% of the variance in ODQ-ID scores was explained by Full Scale IQ. Between group comparisons controlling for intelligence did not yield any significant differences. The shortened SDQ-ID and ODQ-ID have promising psychometric properties, and their component structures appear robust. Differences between men with and without IDs on these two measures of social desirability can be accounted for by differences in general intellectual functioning. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Novel ID-based anti-collision approach for RFID

    Science.gov (United States)

    Zhang, De-Gan; Li, Wen-Bin

    2016-09-01

    Novel correlation ID-based (CID) anti-collision approach for RFID under the banner of the Internet of Things (IOT) has been presented in this paper. The key insights are as follows: according to the deterministic algorithms which are based on the binary search tree, we propose a method to increase the association between tags so that tags can initiatively send their own ID under certain trigger conditions, at the same time, we present a multi-tree search method for querying. When the number of tags is small, by replacing the actual ID with the temporary ID, it can greatly reduce the number of times that the reader reads and writes to tag's ID. Active tags send data to the reader by the way of modulation binary pulses. When applying this method to the uncertain ALOHA algorithms, the reader can determine the locations of the empty slots according to the position of the binary pulse, so it can avoid the decrease in efficiency which is caused by reading empty slots when reading slots. Theory and experiment show that this method can greatly improve the recognition efficiency of the system when applied to either the search tree or the ALOHA anti-collision algorithms.

  19. 76 FR 46835 - Notice of Submission of Proposed Information Collection to OMB; HUD Loan Sales Bidder...

    Science.gov (United States)

    2011-08-03

    ... public comments on the subject proposal. The Bidder Qualifications Statement solicits from prospective... (name of purchaser, corporation entity, address, tax ID), business type, net worth and equity size. By... Information and its Proposed Use: The Bidder Qualifications Statement solicits from prospective bidders the...

  20. Increasing Effectiveness of IDS to Improve Security in Intranet

    Directory of Open Access Journals (Sweden)

    Umesh K. Singh

    2005-01-01

    Full Text Available Today Intrusion Detection Systems (IDS are becoming one of the most important tools for intranet security. Research regarding Intrusion Detection Systems (IDSs has become more active with the recent increases in illegal accesses to computer systems. Many researchers focus only on the techniques or mechanisms for detecting intrusions automatically, without considering the security of IDSs themselves. When an intruder attacks and breaks into a system, he or she often deletes system logs and stops auditing processes. Thus, the security of an intrusion detection system is an important aspect of intrusion detection. This study explores the methods for increasing effectiveness in configurations of an IDS for obtaining maximum effects in security in an intranet. We also discuss the hurdles that have blocked successful measurements in this area and present suggestions for improving effectiveness of an IDS.

  1. A Dynamic ID-based Remote User Authentication Scheme

    CERN Document Server

    Das, Manik Lal; Gulati, Ved P

    2004-01-01

    Password-based authentication schemes are the most widely used techniques for remote user authentication. Many static ID-based remote user authentication schemes both with and without smart cards have been proposed. Most of the schemes do not allow the users to choose and change their passwords, and maintain a verifier table to verify the validity of the user login. In this paper we present a dynamic ID-based remote user authentication scheme using smart cards. Our scheme allows the users to choose and change their passwords freely, and do not maintain any verifier table. The scheme is secure against ID-theft, and can resist the reply attacks, forgery attacks, guessing attacks, insider attacks and stolen verifier attacks.

  2. Effect of ingredients on sensory profile of idli.

    Science.gov (United States)

    Durgadevi, Manoharan; Shetty, Prathapkumar H

    2014-09-01

    Idli is a traditional fermented food and is consumed in India and Srilanka. The objective of the present study is to select the ingredients for optimum desirable product characteristics and to identify the optimum ratios of ingredients and fermentation time with respect to sensory attributes using Response Surface Methodology (RSM). The sensory attributes included were color, appearance, texture, taste and overall quality. Preliminary trials were conducted using five variants of rice and common black gram dhal before framing a model using Central Composite Rotatable Design (CCRD). From the study it was found that a desirable score of 0.7439 was obtained for sensory attributes of idli made with the ratio of 3: 1.475 for IR20 idli rice and ADT3 variety black gram (with husk removed after soaking) fermented for 10.2 h. Principal Component Analysis (PCA) helped to discriminate the samples and attributes within the data matrix, depending upon their inter relationships.

  3. Test and calibration of the IDS fast-timing electronics

    CERN Document Server

    AUTHOR|(CDS)2160817

    2016-01-01

    The ISOLDE decay station(IDS) is one of the permanent experimental setups at the ISOLDE facility of CERN. IDS is used to study decay properties of radioactive nuclei. Thus, fast-timing electronics are necessary for extracting nuclear half-lives. The aims of this work are testing and optimization of the IDS fast-timing electronics as well as measuring a nuclear level half-life in the decay of $^{152}$Eu. The energy resolution of LaBr$_3$ $\\gamma$-detectors was characterized and optimized. A nuclear level lifetime of $^{152}$Eu was measured after obtaining the best parameters for energy resolution and time walk. Dedicated sorting scripts were developed in ROOT in order of perform the characterization and optimization automatically.

  4. The Danish eID Case: Twenty years of Delay

    DEFF Research Database (Denmark)

    Hoff, Jens Villiam; Hoff, Frederik Villiam

    2010-01-01

    The focus of this article is to explain why there is still no qualified digital signature in Denmark as defined by the EU eSignatures Directive nor any other nationwide eID even though Denmark had an early start in eGovernment, and a high level of "e-readiness" compared to other nations. Laying out...... of intergovernmental coordination and lack of cooperation between public and private sector. However, with the recent tender on digital signatures won by the PBS and the roll-out of the NemID it seems that Denmark will finally - after twenty years of delay - have an eID which can be widely used in the public as well...

  5. Generating Decision Trees Method Based on Improved ID3 Algorithm

    Institute of Scientific and Technical Information of China (English)

    Yang Ming; Guo Shuxu1; Wang Jun3

    2011-01-01

    The ID3 algorithm is a classical learning algorithm of decision tree in data mining.The algorithm trends to choosing the attribute with more values,affect the efficiency of classification and prediction for building a decision tree.This article proposes a new approach based on an improved ID3 algorithm.The new algorithm introduces the importance factor λ when calculating the information entropy.It can strengthen the label of important attributes of a tree and reduce the label of non-important attributes.The algorithm overcomes the flaw of the traditional ID3 algorithm which tends to choose the attributes with more values,and also improves the efficiency and flexibility in the process of generating decision trees.

  6. Memristor Crossbar-based Hardware Implementation of IDS Method

    CERN Document Server

    Merrikh-Bayat, Farnood; Rohani, Ali

    2010-01-01

    Ink Drop Spread (IDS) is the engine of Active Learning Method (ALM), which is the methodology of soft computing. IDS, as a pattern-based processing unit, extracts useful information from a system subjected to modeling. In spite of its excellent potential in solving problems such as classification and modeling compared to other soft computing tools, finding its simple and fast hardware implementation is still a challenge. This paper describes a new hardware implementation of IDS method based on the memristor crossbar structure. In addition of simplicity, being completely real-time, having low latency and the ability to continue working after the occurrence of power breakdown are some of the advantages of our proposed circuit.

  7. A Simple Quantum Integro-Differential Solver (SQuIDS)

    CERN Document Server

    Delgado, Carlos Alberto Arguelles; Weaver, Christopher N

    2014-01-01

    Simple Quantum Integro-Differential Solver (SQuIDS) is a C++ code designed to solve semi-analytically the evolution of a set of density matrices and scalar functions. This is done efficiently by expressing all operators in an SU(N) basis. SQuIDS provides a base class from which users can derive new classes to include new non-trivial terms from the right hand sides of density matrix equations. The code was designed in the context of solving neutrino oscillation problems, but can be applied to any problem that involves solving the quantum evolution of a collection of particles with Hilbert space of dimension up to six.

  8. ID-based Key-insulated Authenticated Key Agreement Protocol

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yuan; CHENG Xiao-ming; CHAI Zhen-chuan

    2007-01-01

    The basic idea behind an ID-based cryptosystem is that end user's public key can be determined by his identity information. Comparing with the traditional certificate-based cryptography, identity-based cryptography can eliminate much of the overhead associated with the deployment and management of certificate. However, exposure of private keys can be the most devastating attack on a public key based cryptosystem since such that all security guarantees are lost. In this paper, an ID-based authenticated key agreement protocol was presented. For solving the problem of key exposure of the basic scheme, the technique of key insulation was applied and a key insulated version is developed.

  9. Characteristics of Beijing Psychological Crisis Hotline callers with the diagnosis of mental disorders%北京市心理援助热线有精神障碍诊断史求助者的特征

    Institute of Scientific and Technical Information of China (English)

    王翠玲; 赵丽婷; 范宏振; 安静; 李献云; 王绍礼

    2015-01-01

    Objective:To understand the characteristics of the callers with the diagnosis of mental disorders called Beijing Psychological Crisis Hotline for help,in order to provide specific psychological intervention services for them in future.Methods:From December 2002 to December 2008,24217 different callers'data collected from a computer-based operating system of the Beijing Psychological Crisis Hotline were analyzed.According to their self-reported of having the diagnoses of mental disorder or not,the callers were divided into the ones with diagnosis (n=6516)and the ones without diagnosis (n =17701).The callers'demographic characteristics,their main counseling problems and the suicide-related factors in the two groups were compared.Results:The top five main counseling problems in the group with diagnosis were mental problems,the mental illness related knowledge,the problems of family relationships,working problems and interpersonal problems.Mental problem ranked first in both groups.Compared to the group without diagnosis,the diagnosed ones were more likely to be found in such group of people as women,aged between 20 -29 and 30 -44,having 10 or more years of education and the unem-ployed.The results of the assessments of 11 suicide-related risk factors showed that callers with diagnoses had higher prevalence of most suicide-related factors than those in the other group(P <0.001 or 0.05),which included suicidal intention and behavior while calling,history of attempted suicide,severe depressive symptoms,severe physi-cal illness,history of being abused,afraid of being attacked,suicidal history of relatives or associates,severe of hopeless.Conclusion:The hotline counselors should be aware of the necessity of assessing the severity of depres-sion and other suicide-related factors for the callers with mental disorder diagnoses before providing any psychologi-cal intervention.Moreover,except for providing interventions on the callers'psychiatric problems,the hotline coun

  10. Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L. Huds. essential oil

    Directory of Open Access Journals (Sweden)

    Haris Nikšić

    2012-12-01

    Full Text Available Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC of essential oil from Mentha longifolia (L. Huds. Aim of this study to investigate the quality, antimicrobial andantioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina.Methods: The chemical profi le of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS and thin-layer chromatography (TLC. Antimicrobial activity was tested against 6bacterial strains. RSC was assessed by measuring the scavenging activity of essential oils on 2,2- diphenyl-1-picrylhydrazil (DPPH.Results: The main constituents of the essential oil of M. longifoliae folium were oxygenated monoterpenes,piperitone oxide (63.58% and 1,8-cineole (12.03%. Essential oil exhibited very strong antibacterial activity.The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY. Antioxidant activity was evaluated as a RSC. Investigated essential oil was able to reduce DPPH radicals into the neutral DPPHH form (IC50=10.5 μg/ml and this activity was dose –dependent.Conclusion: The study revealed signifi cant antimicrobial activity of the investigated essential oil. The examined oil exhibited high RSC, which was found to be in correlation to the content of mainly monoterpeneketones and aldehydes. These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals.

  11. Imagery Measures of Ego, Id, Superego, and Identity: Validity Studies.

    Science.gov (United States)

    Cartwright, D.; DeBruin, J.

    1988-01-01

    Five validity studies of the id, ego, superego, and identity scales of the Study of Imagery are reported, using undergraduate students. Multistage Bonferroni procedures are used to evaluate the significance of results. The scales are related to each other and to toughmindedness, self-control, and behavioral conflict. (TJH)

  12. 59 FR- Realty Action; Ada and Owyhee, ID

    Science.gov (United States)

    1994-05-03

    ...-332A-02; IDI-29516] Realty Action; Ada and Owyhee, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Realty Action--IDI-29516; Exchange of public and private lands in Ada and Owyhee.... Containing 640 acres, more or less, in Owyhee County. The purpose of this exchange is to dispose of...

  13. Chronic arsenic intoxication diagnostic score (CAsIDS).

    Science.gov (United States)

    Dani, Sergio Ulhoa; Walter, Gerhard Franz

    2017-08-31

    Arsenic and its compounds are well-established, potent, environmentally widespread and persistent toxicants with metabolic, genotoxic, mutagenic, teratogenic, epigenetic and carcinogenic effects. Arsenic occurs naturally in the Earth's crust, but anthropogenic arsenic emissions have surmounted the emissions from important natural sources such as volcanism. Inorganic arsenicals exhibit acute and chronic toxicities in virtually all cell types and tissues, and hence arsenic intoxication affects multiple systems. Whereas acute arsenic intoxication is rare and relatively easy to diagnose, chronic arsenic intoxication (CAsI) is common but goes often misdiagnosed. Based on a review of the literature as well as our own clinical experience, we propose a chronic arsenic intoxication diagnostic score (CAsIDS). A distinctive feature of CAsIDS is the use of bone arsenic load as an essential criterion for the individual risk assessment of chronic arsenic intoxication, combined with a systemic clinical assessment. We present clinical examples where CAsIDS is applied for the diagnosis of CAsI, review the main topics of the toxicity of arsenic in different cell and organ systems and discuss the therapy and prevention of disease caused or aggravated by chronic arsenic intoxication. CAsIDS can help physicians establish the diagnosis of CAsI and associated conditions. Copyright © 2017 John Wiley & Sons, Ltd.

  14. 76 FR 33651 - Approval and Promulgation of Implementation Plans; ID

    Science.gov (United States)

    2011-06-09

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Implementation Plans; ID AGENCY: Environmental... Implementation Plan (SIP) that were submitted to EPA by the State of Idaho on April 16, 2007. This SIP submittal... through 668. Sec. 52.670 Identification of plan. * * * * * (c) * * * EPA-Approved Idaho Regulations State...

  15. Evolution of the ID Process at Sprint: A Practitioner's Perspective.

    Science.gov (United States)

    Beard, Michael W.

    1999-01-01

    Provides instructional developers' (ID) insights and observations based on the experiences of a training and development organization, Sprint's University of Excellence (UE), as it evolved from a small group of 20-25 individuals in 1990 to a large business unit comprising almost 400 individuals in 1999. Discussion includes course development…

  16. Student ID Cards: What You Should Know About Them

    Science.gov (United States)

    Hoffman, Jonathan; McGuire, Agnes C.

    1973-01-01

    Discusses the usefulness of photo ID cards for school security purposes, library control, student activities, and bus transportation control. Examines ways in which card costs can be reduced and the pros and cons of producing the cards at the school or of letting the work out. Problems involving card abuse and student rights are also considered.…

  17. LED-ID System: Coverage And Fast Link Recovery Technique

    Directory of Open Access Journals (Sweden)

    Muhammad Shahin Uddin

    2012-11-01

    Full Text Available Recently Light Emitting Diodes (LEDs are considered to represent the next generation of lighting and communication technology. LED-ID (Light Emitting Diode – Identification is one of the key technologies for identification, data transmission and illumination simultaneously. This is the new paradigm in theidentification technology environment. LED-ID system typically needs line of sight (LOS to support narrow FOV transceivers links to achieve high data rate but reduced the coverage, increase the disconnection rate of the link. Also when the receiver moves horizontally or vertically, in that case coverage also varied and LOS relies upon direct link between transmitter and receiver. Link recovery is a new challenge for reliable LED-ID system. Fast link recovery techniques are essential for the making the system robust. In this paper we discuss about the horizontal and vertical coverage variation in terms of received power and fast link recovery technique for the LED-ID system considering both LOS and NLOS reflection.

  18. Sequence ID and annotation information - Gclust Server | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us Gclust Server Sequence ID and annotation information Data detail Data name Sequence ID and ann...e specifying the ID, length and annotation information of the amino acid sequences of the predicted proteins...f amino acid sequence (Sequence ID) Field 2 Length of amino acid sequence Field 3 Ann...of This Database Site Policy | Contact Us Sequence ID and annotation information - Gclust Server | LSDB Archive ...

  19. Subgroups associated with lower physical fitness in older adults with ID : Results of the HA-ID study

    NARCIS (Netherlands)

    Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2014-01-01

    Although physical fitness is generally very low in older adults with intellectual disabilities (ID), levels may differ across subgroups. It is important to identify which subgroups need to be targeted specifically in physical activity and fitness interventions and reference values. Physical fitness

  20. Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2

    NARCIS (Netherlands)

    Buitenhuis, M; van Deutekom, HWM; Verhagen, LP; Castor, A; Jacobsen, SEW; Lammers, JWJ; Koenderman, L; Coffer, PJ

    2005-01-01

    Inhibitor of DNA binding (Id) proteins function as inhibitors of members of the basic helix-loop-helix family of transcription factors and have been demonstrated to play an important role in regulating lymphopoiesis. However, the role of these proteins in regulation of myelopoiesis is currently

  1. Impact of the safener Mefenpyr-diethyl on herbicide resistance evolution in Alopecurus myosuroides (Huds. biotypes

    Directory of Open Access Journals (Sweden)

    Rosenhauer, Maria

    2016-02-01

    Full Text Available The evolution of herbicide resistance is an important topic in plant protection and agricultural practice. Safeners are commonly used in herbicides to protect crops against herbicidal damage. Although no effect on the weed control is expected, it has been theorized that the rate of evolution of non-target site resistance (NTSR in weeds in cereals may be enhanced by use of herbicide products containing safeners. One of the most important safeners in cereals is mefenpyr-diethyl. Therefore, the possible influence of mefenpyr on herbicide resistance was studied in cooperative trials between Bayer CropScience (BCS, F-Höchst and FH Bingen. The trials tested in parallel different herbicide resistant black-grass (Alopecurus myosuroides (Huds. biotypes under greenhouse conditions. The biotypes where chosen due to known NTSR against Atlantis WG® (4 highly resistant and 5 moderately resistant as well as two susceptible biotypes. The populations were treated with the following three herbicide/safener regimes in six concentrations adjusted according to the anticipated biotype resistance levels. (1 mesosulfuron + iodosulfuron + without safener formulation, (2 mesosulfuron + iodosulfuron + constant mefenpyr concentration (45g/ha, (3 mesosulfuron + iodosulfuron + varying mefenpyr concentrations (ratio 5:1:15. The treatments were applied in post-emergence based on mesosulfuron to iodosulfuron ratios in Atlantis WG® (5:1. The trials were assessed visually (% effect and by fresh weight. Dose-response curves were performed and ED50 values for each treatment and biotype were calculated. Results showed a varying effect of safeners which was in the most cases negligible. Depending on the biotypes mostly no impact on the safener was found for herbicide resistance. In conclusion, the trials from Bingen and F-Höchst gave evidence, that there is no significant and consistent influence of the safener mefenpyr on evolution of NTSR black-grass.

  2. ID-Based Fair Off-Line Electronic Cash System with Multiple Banks

    Institute of Scientific and Technical Information of China (English)

    Chang-Ji Wang; Yong Tang; Qing Li

    2007-01-01

    ID-based public key cryptography (ID-PKC) has many advantages over certificate-based public key cryptog-raphy (CA-PKC), and has drawn researchers’ extensive attention in recent years. However, the existing electronic cash schemes are constructed under CA-PKC, and there seems no electronic cash scheme under ID-PKC up to now to the best of our knowledge. It is important to study how to construct electronic cash schemes based on ID-PKC from views on both practical perspective and pure research issue. In this paper, we present a simpler and provably secure ID-based restrictive partially blind signature (RPBS), and then propose an ID-based fair off-line electronic cash (ID-FOLC) scheme with multiple banks based on the proposed ID-based RPBS. The proposed ID-FOLC scheme with multiple banks is more efficient than existing electronic cash schemes with multiple banks based on group blind signature.

  3. Entitlement Management: Ready to Enter the IdM Mainstream

    Science.gov (United States)

    Gebel, Gerry; Wang, Alice

    Externalizing authorization processing from business applications has been a goal for architects and developers for many years. Recent compliance demands for more granular access control and policy transparency have increased the urgency to adopt an architectural model where authorization and entitlement management are consumed as a service rather than embedded within business applications. Major software vendors, such as Microsoft, Oracle, and SAP, are making significant steps to separate IdM functionality, including entitlement management from application logic. The market has also responded with a plethora of products that provide entitlement management and authorization functionality for commercial or custom-built application environments. Finally, the Extensible Access Control Markup Language (XACML) has emerged as the consensus authorization standard being supported by a growing number of IT and application vendors. Collectively, these forces form the basis of a nascent IdM market segment referred to as entitlement management.

  4. La I+D en las pymes: Intensidad y estrategia

    Directory of Open Access Journals (Sweden)

    Anna Arbussà

    2004-01-01

    Full Text Available ¿Es importante la innovación en las pequeñas y medianas empresas? ¿De qué dependen sus estrategias de inversión en I+D? En este artículo respondemos a estas preguntas basándonos en nuevos datos obtenidos sobre una muestra de pymes catalanas. Explicamos cómo varía la intensidad de la I+D según sean la demanda, la oportunidad tecnológica y las condiciones de apropiabilidad en el sector industrial donde se halle la empresa; y presentamos las estrategias de desarrollo interno y adquisición externa de tecnología seguidas por las empresas más competitivas.

  5. De l'idée au businessplan

    OpenAIRE

    Frey, Urs

    2012-01-01

    La création est l'une des nombreuses voies pour arriver à sa propre entreprise. Si vous choisissez cette voie, il est déterminant, pour le succès ultérieur de votre jeune entreprise, que la planification et la mise en oeuvre soient optimales. Le businessplan a pour but de détailler pas à pas l'idée d'entreprise, d'opposer les opportunités aux risques et d'élaborer des budgets. Nous vous indiquons les obstacles que vous pouvez rencontrer sur ce chemin, de l'idée à la création d'une entreprise ...

  6. A NEW EFFICIENT ID-BASED PROXY BLIND SIGNATURE SCHEME

    Institute of Scientific and Technical Information of China (English)

    Ming Yang; Wang Yumin

    2008-01-01

    In a proxy blind signature scheme, the proxy signer is allowed to generate a blind signature on behalf of the original signer. The proxy blind signature scheme is useful in several applications such as e-voting, e-payment, etc. Recently, Zheng, et al. presented an IDentity (ID)-based proxy blind signature. In this paper, a new efficient ID-based proxy blind signature scheme from bilinear pairings is proposed, which can satisfy the security properties of both the proxy signatures and the blind signature schemes. Analysis of the scheme efficiency shows that the new scheme is more efficient than Zheng, et al.'s scheme. The proposed scheme is more practical in the real world.

  7. Tailoring a corporate compliance program for an IDS.

    Science.gov (United States)

    Berkey, M F

    1999-01-01

    Integrated delivery systems (IDSs) face a particular challenge in implementing a corporate compliance program--that of ensuring the program addresses issues of compliance with payment rules and regulations consistently across every component of the health system. To successfully implement an effective compliance program, the various components of the IDS first must understand what such a program is intended to accomplish, and any internal resistance to developing the program must be overcome. The IDS then can undertake identifying and assessing areas of the health system at risk of being in noncompliance, designing and implementing the program, auditing claims processing and cost reporting throughout the health system to ensure systemwide compliance, and maintaining the program through ongoing monitoring and training.

  8. ID-kaart on mugav ja praktiline dokument / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1949-

    2001-01-01

    Ilmunud ka: Severnoje Poberezhje 12. okt., lk. 2; Lääne Elu 13. okt., lk. 2; Hiiumaa 13. okt., lk. 2; Koit 16. okt., lk. 6; Nädaline 16. okt., lk. 4; Sakala 18. okt., lk. 2; Valgamaalane 18. okt., lk. 2; Pjarnuskii Ekspress 12. okt., lk. 2; Meie Maa 19. okt., lk. 2; Hiiu Leht 23. okt., lk. 2; Järva Teataja 30. okt., lk. 2. Siseministri nõunik Heiki Raudla ID-kaardist

  9. Guinea pig ID-like families of SINEs.

    Science.gov (United States)

    Kass, David H; Schaetz, Brian A; Beitler, Lindsey; Bonney, Kevin M; Jamison, Nicole; Wiesner, Cathy

    2009-05-01

    Previous studies have indicated a paucity of SINEs within the genomes of the guinea pig and nutria, representatives of the Hystricognathi suborder of rodents. More recent work has shown that the guinea pig genome contains a large number of B1 elements, expanding to various levels among different rodents. In this work we utilized A-B PCR and screened GenBank with sequences from isolated clones to identify potentially uncharacterized SINEs within the guinea pig genome, and identified numerous sequences with a high degree of similarity (>92%) specific to the guinea pig. The presence of A-tails and flanking direct repeats associated with these sequences supported the identification of a full-length SINE, with a consensus sequence notably distinct from other rodent SINEs. Although most similar to the ID SINE, it clearly was not derived from the known ID master gene (BC1), hence we refer to this element as guinea pig ID-like (GPIDL). Using the consensus to screen the guinea pig genomic database (Assembly CavPor2) with Ensembl BlastView, we estimated at least 100,000 copies, which contrasts markedly to just over 100 copies of ID elements. Additionally we provided evidence of recent integrations of GPIDL as two of seven analyzed conserved GPIDL-containing loci demonstrated presence/absence variants in Cavia porcellus and C. aperea. Using intra-IDL PCR and sequence analyses we also provide evidence that GPIDL is derived from a hystricognath-specific SINE family. These results demonstrate that this SINE family continues to contribute to the dynamics of genomes of hystricognath rodents.

  10. FastID: Extremely Fast Forensic DNA Comparisons

    Science.gov (United States)

    2017-05-19

    FastID: Extremely Fast Forensic DNA Comparisons Darrell O. Ricke, PhD Bioengineering Systems & Technologies Massachusetts Institute of...Technology Lincoln Laboratory Lexington, MA USA Darrell.Ricke@ll.mit.edu Abstract—Rapid analysis of DNA forensic samples can have a critical impact on...time sensitive investigations. Analysis of forensic DNA samples by massively parallel sequencing is creating the next gold standard for DNA

  11. ID-kaart on mugav ja praktiline dokument / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1949-

    2001-01-01

    Ilmunud ka: Severnoje Poberezhje 12. okt., lk. 2; Lääne Elu 13. okt., lk. 2; Hiiumaa 13. okt., lk. 2; Koit 16. okt., lk. 6; Nädaline 16. okt., lk. 4; Sakala 18. okt., lk. 2; Valgamaalane 18. okt., lk. 2; Pjarnuskii Ekspress 12. okt., lk. 2; Meie Maa 19. okt., lk. 2; Hiiu Leht 23. okt., lk. 2; Järva Teataja 30. okt., lk. 2. Siseministri nõunik Heiki Raudla ID-kaardist

  12. El sistema español de I+D

    Directory of Open Access Journals (Sweden)

    López Facal, Javier

    1997-06-01

    Full Text Available Not available.Para centrar el lugar que ocupan las Bibliotecas y Centros de documentación en el Sistema de I+D, se resume la evolución de la política científica española desde los años cincuenta y se describe la estructura actual de este sistema, sus magnitudes principales y sus deficiencias.

  13. Applying Fuzzy ID3 Decision Tree for Software Effort Estimation

    CERN Document Server

    Elyassami, Sanaa

    2011-01-01

    Web Effort Estimation is a process of predicting the efforts and cost in terms of money, schedule and staff for any software project system. Many estimation models have been proposed over the last three decades and it is believed that it is a must for the purpose of: Budgeting, risk analysis, project planning and control, and project improvement investment analysis. In this paper, we investigate the use of Fuzzy ID3 decision tree for software cost estimation; it is designed by integrating the principles of ID3 decision tree and the fuzzy set-theoretic concepts, enabling the model to handle uncertain and imprecise data when describing the software projects, which can improve greatly the accuracy of obtained estimates. MMRE and Pred are used as measures of prediction accuracy for this study. A series of experiments is reported using two different software projects datasets namely, Tukutuku and COCOMO'81 datasets. The results are compared with those produced by the crisp version of the ID3 decision tree.

  14. Applying Fuzzy ID3 Decision Tree for Software Effort Estimation

    Directory of Open Access Journals (Sweden)

    Ali Idri

    2011-07-01

    Full Text Available Web Effort Estimation is a process of predicting the efforts and cost in terms of money, schedule and staff for any software project system. Many estimation models have been proposed over the last three decades and it is believed that it is a must for the purpose of: Budgeting, risk analysis, project planning and control, and project improvement investment analysis. In this paper, we investigate the use of Fuzzy ID3 decision tree for software cost estimation; it is designed by integrating the principles of ID3 decision tree and the fuzzy set-theoretic concepts, enabling the model to handle uncertain and imprecise data when describing the software projects, which can improve greatly the accuracy of obtained estimates. MMRE and Pred are used as measures of prediction accuracy for this study. A series of experiments is reported using two different software projects datasets namely, Tukutuku and COCOMO'81 datasets. The results are compared with those produced by the crisp version of the ID3 decision tree.

  15. Drosophila melanogaster-based screening for multihost virulence factors of Pseudomonas aeruginosa PA14 and identification of a virulence-attenuating factor, HudA.

    Science.gov (United States)

    Kim, Seol-Hee; Park, Shin-Young; Heo, Yun-Jeong; Cho, You-Hee

    2008-09-01

    Pseudomonas aeruginosa is an important opportunistic human pathogen that interacts with phylogenetically diverse nonmammalian hosts, including plants, nematodes, and insects. Here, we exploited the P. aeruginosa-induced killing of the fruit fly Drosophila melanogaster as an assay system to screen for virulence-attenuated mutants of P. aeruginosa PA14. Fifteen nonredundant mutants were isolated from 4,018 random transposon (TnphoA) insertion clones, and 13 out of them (86.7%) displayed significantly reduced virulence in a murine peritonitis model as well. The TnphoA insertion sites of the 15 mutants were determined; already known virulence genes (dsbA, pvdI, fhlB, pilF, and wspF) and new virulence genes such as PA0253 (hudR), PA0369, PA2077, PA0272, PA2113, PA2965 (fabF1), and PA2002 were identified; one insertion was located at the intergenic region between PA1928 and PA1929; and the other two insertions were located in the genes (PA14_35740 and PA14_36000) within a putative genomic island, indicating a potential pathogenicity island of PA14. Further characterization of hudR, a virulence gene which encodes a MarR/SlyA family transcription factor, revealed that elevated expression of PA0254 (hudA [homologous to UbiD]) was necessary and sufficient for the virulence attenuation of the hudR mutant. The HudR protein repressed the hudAR operon by directly binding to its upstream promoter region. Collectively, these results validate the relevance of the D. melanogaster model for the high-throughput identification of new virulence factors involved in the multihost pathogenesis of P. aeruginosa.

  16. 78 FR 8596 - Hartford Financial Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS...

    Science.gov (United States)

    2013-02-06

    .../ Information Delivery Services (IDS)/Corporate & Financial Reporting Group, Hartford, CT; Notice of Negative... Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS)/Corporate & Financial... Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services...

  17. Field experiences with recent ALS-inhibitors on herbicide resistant blackgrass (Alopecurus myosuroides Huds.).

    Science.gov (United States)

    Desmet, E M; Bulcke, R; Maeghe, L

    2004-01-01

    In the growing season 2002-2003 two field experiments were carried out in winter wheat on the heavy clay soil of the coastal polder area at Zevekote to study the response of blackgrass (Alopecurus myosuroides Huds.) resistant or somewhat less sensitive to a wide variety of herbicides (clodinafop-propargyl, fenoxaprop-P-ethy1; flupyrsulfuron-methyl+metsulfuron-methyl, propoxycarbazone-sodium; isoproturon) representing various modes of action. In Experiment 1, preemergence applications of isoproturon+diflufenican (1500+187.5 g/ha) and isoproturon+diflufenican+flurtamone (1250+100+250 g/ha) respectively were followed in mid-March (Zadoks: 23) by one of the following treatments: none, propoxycarbazone-sodium + vegetable oil (42 g/ha + 1 l/ha), mesosulfuron-methyl + iodosulfuron-methyl-sodium (+mefenpyr-diethyl) + vegetable oil (15+3 (+45) g/ha + 1 l/ha), clodinafop-propargyl (+cloquintocet-mexyl) {60 (+15) g/ha} and flupyrsulfuron-methyl+metsulfuron-methyl (10+5 g/ha). Systems based on clodinafop-propargyl, propoxycarbazone-sodium or flupyrsulfuron-methyl+metsulfuron-methyl resulted in poor supplementary control of blackgrass compared to preemergence herbicide application only. On the contrary, systems based on postemergence application of mesosulfuron-methyl + iodosulfuron-methyl-sodium resulted in excellent control. In most cases the few surviving plants failed to produce inflorescences. In Experiment 2, fall applications in the 3 leaves stage (Zadoks: 13) of prosulfocarb + isoxaben (4000+75 g/ha), flufenacet + diflufenican + isoxaben (240+120+75 g/ha) and flufenacet + pendimethalin + chlorotoluron (180+900+1000 g/ha) respectively were followed in mid-March (Zadoks: 23) by one of the following treatments: none, propoxycarbazone-sodium + vegetable oil (42 g/ha+l l/ha), mesosulfuron-methyl + iodosulfuron-methyl-sodium (+mefenpyr-diethyl) + vegetable oil {15+3 (+45) g/ha + 1 l/ha}, clodinafop-propargyl (+cloquintocet-mexyl) {60 (+15) g/ha}, flupyrsulfuron

  18. Iron deficiency (ID) at both birth and 9 months predicts right frontal EEG asymmetry in infancy.

    Science.gov (United States)

    Armony-Sivan, Rinat; Zhu, Bingquan; Clark, Katy M; Richards, Blair; Ji, Chai; Kaciroti, Niko; Shao, Jie; Lozoff, Betsy

    2016-05-01

    This study considered effects of timing and duration of iron deficiency (ID) on frontal EEG asymmetry in infancy. In healthy term Chinese infants, EEG was recorded at 9 months in three experimental conditions: baseline, peek-a-boo, and stranger approach. Eighty infants provided data for all conditions. Prenatal ID was defined as low cord ferritin or high ZPP/H. Postnatal ID was defined as ≥ two abnormal iron measures at 9 months. Study groups were pre- and postnatal ID, prenatal ID only, postnatal ID only, and not ID. GLM repeated measure analysis showed a main effect for iron group. The pre- and postnatal ID group had negative asymmetry scores, reflecting right frontal EEG asymmetry (mean ± SE: -.18 ± .07) versus prenatal ID only (.00 ± .04), postnatal ID only (.03 ± .04), and not ID (.02 ± .04). Thus, ID at both birth and 9 months was associated with right frontal EEG asymmetry, a neural correlate of behavioral withdrawal and negative emotions.

  19. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Science.gov (United States)

    2010-01-01

    ... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a) In-person renewals. States must require holders of REAL ID driver's licenses and identification cards to renew...

  20. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Science.gov (United States)

    2010-01-01

    ... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a) State... time a REAL ID driver's license or identification card is reissued, to ensure that the...

  1. Picture This: How to Establish an Effective School ID Card Program

    Science.gov (United States)

    Finkelstein, David

    2013-01-01

    Most school districts do not have an ID card policy that everyone knows and follows, yet. many school districts are implementing ID card programs to address concerns about safety, efficiency, and convenience. A well-thought-out ID card program leads to greater security and smoother operations throughout the school and should thus be a priority.…

  2. People with ID as interviewers and co-researchers: experiences and reflection.

    NARCIS (Netherlands)

    Lieshout, H. van

    2012-01-01

    Aim: To share the experience of working with people with intellectual disabilities (ID) as interviewers in a qualitative study about community participation of people with ID. We reflect on two perspectives: the interviewers and the researchers. Method: Eighteen people with ID were interviewed by th

  3. A role for Id2 in regulating photic entrainment of the mammalian circadian system.

    Science.gov (United States)

    Duffield, Giles E; Watson, Nathan P; Mantani, Akio; Peirson, Stuart N; Robles-Murguia, Maricela; Loros, Jennifer J; Israel, Mark A; Dunlap, Jay C

    2009-02-24

    Inhibitor of DNA binding genes (Id1-Id4) encode helix-loop-helix (HLH) transcriptional repressors associated with development and tumorigenesis [1, 2], but little is known concerning the function(s) of these genes in normal adult animals. Id2 was identified in DNA microarray screens for rhythmically expressed genes [3-5], and further analysis revealed a circadian pattern of expression of all four Id genes in multiple tissues including the suprachiasmatic nucleus. To explore an in vivo function, we generated and characterized deletion mutations of Id2 and of Id4. Id2(-/-) mice exhibit abnormally rapid entrainment and an increase in the magnitude of the phase shift of the pacemaker. A significant proportion of mice also exhibit disrupted rhythms when maintained under constant darkness. Conversely, Id4(-/-) mice did not exhibit a noticeable circadian phenotype. In vitro studies using an mPer1 and an AVP promoter reporter revealed the potential for ID1, ID2, and ID3 proteins to interact with the canonical basic HLH clock proteins BMAL1 and CLOCK. These data suggest that the Id genes may be important for entrainment and operation of the mammalian circadian system, potentially acting through BMAL1 and CLOCK targets.

  4. The Id, the Ego and the Superego of The Simpsons

    OpenAIRE

    Stefán Birgir Stefánsson 1985

    2013-01-01

    The purpose of this essay is to explore three main characters from the popular television series The Simpsons in regards to Sigmund Freud’s theories in psychoanalytical analysis. This exploration is done because of great interest by the author and the lack of psychoanalytical analysis found connected to The Simpsons television show. The main aim is to show that these three characters, Homer Simpson, Marge Simpson and Ned Flanders, represent Freud’s three parts of the psyche, the id, the ego a...

  5. RFID and Auto-ID in planning and logistics

    CERN Document Server

    Jones, Erick C

    2011-01-01

    As RFID technology is becoming increasingly popular, the need has arisen to address the challenges and approaches to successful implementation. RFID and Auto-ID in Planning and Logistics: A Practical Guide for Military UID Applications presents the concepts for students, military personnel and contractors, and corporate managers to learn about RFID and other automatic information capture technologies, and their integration into planning and logistics functions. The text includes comparisons of RFID with technologies such as bar codes, satellite tags, and global positioning systems and provides

  6. ATF3 suppresses ESCC via downregulation of ID1

    Science.gov (United States)

    Li, Jian; Yang, Zishan; Chen, Zhiuguo; Bao, Yonghua; Zhang, Huijuan; Fang, Xinhui; Yang, Wancai

    2016-01-01

    Esophageal cancer is one of the most prevalent forms of cancer and has a particularly high mortality rate due to early metastasis; however, the underlying mechanisms of its formation and progression remain unclear. The present study performed immunohistochemical analysis and observed that the expression of activating transcription factor 3 (ATF3) was reduced in esophageal squamous cell carcinoma (ESCC) in comparison with non-tumor adjacent tissues. By contrast, inhibitor of DNA binding 1 (ID1) was overexpressed in ESCC tissues, demonstrating an inverse correlation with ATF3 (P<0.01). In ESCC EC109 and KYSE450 cells lines, transfection with an ATF3-overexpression plasmid resulted in the inhibition of cell proliferation, motility and migration, which was associated with the induction of E-cadherin expression and inhibition of cyclin D1 and Twist. Notably, ATF3 exerted an inverse regulatory interaction with ID1. The results of the present study provide additional evidence of the tumor suppressive features of ATF3 and demonstrate a novel mechanism of ATF3-mediated inhibition of cancer metastasis in esophageal cancer. PMID:27602100

  7. Intrusion Detection System Inside Grid Computing Environment (IDS-IGCE

    Directory of Open Access Journals (Sweden)

    Basappa B. Kodada

    2012-01-01

    Full Text Available Grid Computing is a kind of important information technology which enables resource sharing globally to solve the large scale problem. It is based on networks and able to enable large scale aggregation and sharing of computational, data, sensors and other resources across institutional boundaries. Integrated Globus Tool Kit with Web services is to present OGSA (Open Grid Services Architecture as the standardservice grid architecture. In OGSA, everything is abstracted as a service, including computers, applications, data as well as instruments. The services and resources in Grid are heterogeneous and dynamic, and they also belong to different domains. Grid Services are still new to business system & asmore systems are being attached to it, any threat to it could bring collapse and huge harm. May be intruder come with a new form of attack. Grid Computing is a Global Infrastructure on the internet has led to asecurity attacks on the Computing Infrastructure. The wide varieties of IDS (Intrusion Detection System are available which are designed to handle the specific types of attacks. The technique of [27] will protect future attacks in Service Grid Computing Environment at the Grid Infrastructure but there is no technique can protect these types of attacks inside the grid at the node level. So this paper proposes the Architecture of IDS-IGCE (Intrusion Detection System – Inside Grid Computing Environment which can provide the protection against the complete threats inside the Grid Environment.

  8. Secure OpenID Authentication Model by Using Trusted Computing

    Directory of Open Access Journals (Sweden)

    E. Ghazizadeh

    2014-01-01

    Full Text Available The growth of Internet online services has been very quick in recent years. Each online service requires Internet users to create a new account to use the service. The problem can be seen when each user usually needs more than one service and, consequently, has numerous accounts. These numerous accounts have to be managed in a secure and simple way to be protected against identity theft. Single sign-on (SSO and OpenID have been used to decrease the complexity of managing numerous accounts required in the Internet identity environment. Trusted Platform Module (TPM and Trust Multitenancy are great trusted computing-based technologies to solve security concerns in the Internet identity environment. Since trust is one of the pillars of security in the cloud, this paper analyzes the existing cloud identity techniques in order to investigate their strengths and weaknesses. This paper proposes a model in which One Time Password (OTP, TPM, and OpenID are used to provide a solution against phishing as a common identity theft in cloud environment.

  9. 24 CFR 1000.116 - What should HUD do before declining a proposal to provide assistance to non low-income Indian...

    Science.gov (United States)

    2010-04-01

    ... a proposal to provide assistance to non low-income Indian families or a model housing activity? 1000... should HUD do before declining a proposal to provide assistance to non low-income Indian families or a... assistance to non low-income Indian families or a model housing activity. To the extent resources...

  10. 24 CFR 1000.114 - How long does HUD have to review and act on a proposal to provide assistance to non low-income...

    Science.gov (United States)

    2010-04-01

    ... and act on a proposal to provide assistance to non low-income Indian families or a model housing... does HUD have to review and act on a proposal to provide assistance to non low-income Indian families... assistance to non low-income Indian families or for model activities is approved or disapproved. If...

  11. HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.

    Directory of Open Access Journals (Sweden)

    Megan Allen

    Full Text Available Complex regulation of brain-derived neurotrophic factor (BDNF governs its intricate functions in brain development and neuronal plasticity. Besides tight transcriptional control from multiple distinct promoters, alternative 3'end processing of the BDNF transcripts generates either a long or a short 3'untranslated region (3'UTR. Previous reports indicate that distinct RNA sequence in the BDNF 3'UTRs differentially regulates BDNF production in the brain to accommodate neuronal activity changes, conceivably through differential interactions with undefined trans-acting factors that regulate stability and translation of these BDNF mRNA isoforms. In this study, we report that the neuronal RNA-binding protein (RBP HuD interacts with a highly conserved AU-rich element (ARE specifically located in the BDNF long 3'UTR. Such interaction is necessary and sufficient for selective stabilization of mRNAs that contain the BDNF long 3'UTR in vitro and in vivo. Moreover, in a HuD transgenic mouse model, the BDNF long 3'UTR mRNA is increased in the hippocampal dentate granule cells (DGCs, leading to elevated expression of BDNF protein that is transported and stored in the mossy fiber (MF terminals. Our results identify HuD as the first trans-acting factor that enhances BDNF expression specifically through the long 3'UTR and a novel mechanism that regulates BDNF protein production in selected neuronal populations by HuD abundance.

  12. Id3 induces an Elk-1–caspase-8-dependent apoptotic pathway in squamous carcinoma cells

    OpenAIRE

    Chen, You-Shin; Aubee, Joseph; Divito, Kyle A.; Zhou, Hengbo; Zhang, Weiyi; Chou, Fen-Pi; Simbulan-Rosenthal, Cynthia M.; Rosenthal, Dean S.

    2015-01-01

    Inhibitor of differentiation/DNA-binding (Id) proteins are helix–loop–helix (HLH) transcription factors. The Id protein family (Id1–Id4) mediates tissue homeostasis by regulating cellular processes including differentiation, proliferation, and apoptosis. Ids typically function as dominant negative HLH proteins, which bind other HLH proteins and sequester them away from DNA promoter regions. Previously, we have found that Id3 induced apoptosis in immortalized human keratinocytes upon UVB expos...

  13. Id4 Promotes Senescence and Sensitivity to Doxorubicin-induced Apoptosis in DU145 Prostate Cancer Cells

    OpenAIRE

    Carey, Jason P; Knowell, Ashley Evans; Chinaranagari, Swathi; Chaudhary, Jaideep

    2013-01-01

    Inhibitor of differentiation proteins (Id1, 2, 3 and 4) are dominant negative regulators of basic helix loop helix transcription factors and play dominant roles in cancer cells, spanning several molecular pathways including senescence, invasion, metastasis, proliferation and apoptosis. In contrast to high Id1, Id2 and Id3 expression, the expression of Id4 is epigenetically silenced in prostate cancer. In the present study we demonstrated a novel role of Id4, that of promotion of cellular sene...

  14. Impaired Thermogenesis and a Molecular Signature for Brown Adipose Tissue in Id2 Null Mice

    Directory of Open Access Journals (Sweden)

    Peng Zhou

    2016-01-01

    Full Text Available Inhibitor of DNA binding 2 (ID2 is a helix-loop-helix transcriptional repressor rhythmically expressed in many adult tissues. Our previous studies have demonstrated that Id2 null mice have sex-specific elevated glucose uptake in brown adipose tissue (BAT. Here we further explored the role of Id2 in the regulation of core body temperature over the circadian cycle and the impact of Id2 deficiency on genes involved in insulin signaling and adipogenesis in BAT. We discovered a reduced core body temperature in Id2−/− mice. Moreover, in Id2−/− BAT, 30 genes including Irs1, PPARs, and PGC-1s were identified as differentially expressed in a sex-specific pattern. These data provide valuable insights into the impact of Id2 deficiency on energy homeostasis of mice in a sex-specific manner.

  15. Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-Occurring ASD and ID

    Science.gov (United States)

    Schieve, Laura A.; Clayton, Heather B.; Durkin, Maureen S.; Wingate, Martha S.; Drews-Botsch, Carolyn

    2015-01-01

    While studies report associations between perinatal outcomes and both autism spectrum disorder (ASD) and intellectual disability (ID), there has been little study of ASD with versus without co-occurring ID. We compared perinatal risk factors among 7547 children in the 2006-2010 Autism and Developmental Disability Monitoring Network classified as…

  16. Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-Occurring ASD and ID

    Science.gov (United States)

    Schieve, Laura A.; Clayton, Heather B.; Durkin, Maureen S.; Wingate, Martha S.; Drews-Botsch, Carolyn

    2015-01-01

    While studies report associations between perinatal outcomes and both autism spectrum disorder (ASD) and intellectual disability (ID), there has been little study of ASD with versus without co-occurring ID. We compared perinatal risk factors among 7547 children in the 2006-2010 Autism and Developmental Disability Monitoring Network classified as…

  17. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H.; Morton, Derrick J.; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep, E-mail: jchaudhary@cau.edu

    2016-09-09

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function. - Highlights: • ID4 expression induces AR expression in PC3 cells, which generally lack AR. • ID4 expression increased apoptosis and decreased cell proliferation and invasion. • Overexpression of ID4 reduces tumor growth of subcutaneous xenografts in vivo. • ID4 induces p21 and FKBP51 expression- co-factors of AR tumor suppressor activity.

  18. Microbe-ID: an open source toolbox for microbial genotyping and species identification

    Directory of Open Access Journals (Sweden)

    Javier F. Tabima

    2016-08-01

    Full Text Available Development of tools to identify species, genotypes, or novel strains of invasive organisms is critical for monitoring emergence and implementing rapid response measures. Molecular markers, although critical to identifying species or genotypes, require bioinformatic tools for analysis. However, user-friendly analytical tools for fast identification are not readily available. To address this need, we created a web-based set of applications called Microbe-ID that allow for customizing a toolbox for rapid species identification and strain genotyping using any genetic markers of choice. Two components of Microbe-ID, named Sequence-ID and Genotype-ID, implement species and genotype identification, respectively. Sequence-ID allows identification of species by using BLAST to query sequences for any locus of interest against a custom reference sequence database. Genotype-ID allows placement of an unknown multilocus marker in either a minimum spanning network or dendrogram with bootstrap support from a user-created reference database. Microbe-ID can be used for identification of any organism based on nucleotide sequences or any molecular marker type and several examples are provided. We created a public website for demonstration purposes called Microbe-ID (microbe-id.org and provided a working implementation for the genus Phytophthora (phytophthora-id.org. In Phytophthora-ID, the Sequence-ID application allows identification based on ITS or cox spacer sequences. Genotype-ID groups individuals into clonal lineages based on simple sequence repeat (SSR markers for the two invasive plant pathogen species P. infestans and P. ramorum. All code is open source and available on github and CRAN. Instructions for installation and use are provided at https://github.com/grunwaldlab/Microbe-ID.

  19. Radikal konservativ idédebat og højreautoritær fascination i Danmark, ca. 1928-1940

    DEFF Research Database (Denmark)

    Holm, Adam

    1999-01-01

    Historie, Højreradikalisme, Konservatisme, Fascisme, Mellemkrigstid, Idéhistorie, Intellektuelle......Historie, Højreradikalisme, Konservatisme, Fascisme, Mellemkrigstid, Idéhistorie, Intellektuelle...

  20. Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory

    Science.gov (United States)

    Pascale, Alessia; Gusev, Pavel A.; Amadio, Marialaura; Dottorini, Tania; Govoni, Stefano; Alkon, Daniel L.; Quattrone, Alessandro

    2004-01-01

    Neuronal ELAV-like proteins (HuB, HuC, and HuD) are highly conserved RNA-binding proteins able to selectively associate with the 3′ UTR of a subset of target mRNAs and increase their cytoplasmic stability and rate of translation. We previously demonstrated the involvement of these proteins in learning, reporting that they undergo a sustained up-regulation in the hippocampus of mice trained in a spatial discrimination task. Here, we extend this finding, showing that a similar up-regulation occurs in the hippocampus of rats trained in another spatial learning paradigm, the Morris water maze. HuD, a strictly neuron-specific ELAV-like protein, is shown to increase after learning, with a preferential binding to the cytoskeletal fraction. HuD up-regulation is associated with an enhancement of GAP-43 mRNA and protein levels, with an apparently increased HuD colocalization with the GAP-43 mRNA and an increased association of neuronal ELAV-like proteins with the GAP-43 mRNA. These learning-dependent biochemical events appear to be spatiotemporally controlled, because they do not occur in another brain region involved in learning, the retrosplenial cortex, and at the level of protein expression they show extinction 1 month after training despite memory retention. By contrast, HuD mRNA levels still remain increased after 1 month in the CA1 region. This persistence may have implications for long-term memory recall. PMID:14745023

  1. Herbicide treatments for the control of resistant black grass (Alopecurus myosuroides Huds. in winter wheat (Triticum aestivum L.

    Directory of Open Access Journals (Sweden)

    Gehring, Klaus

    2014-02-01

    Full Text Available Different herbicide treatments were tested in the year 2010 – 2013 at eight locations in the north-west of Bavaria in Franken to control herbicide resistant black grass (Alopecurus myosuroides, Huds.. Application of Atlantis (Mesosulfuron + Iodosulfuron + Mefenpyr was essential for the control of black grass in winter wheat. Combination with other herbicides was also in focus of the trial program as different treatment methods, application timing, application sequences, herbicide rate and the use of adjuvants. As a result of the trials sequence applications were more effective than single applications. The use of soil active herbicides in autumn and spring application of Atlantis was one of the best solutions to control resistant black grass in winter wheat. Reduced rate of Atlantis have to be compensated by addition of appropriate adjuvants. Higher level of resistance depends on implementation of integrated weed management to serve economic wheat production.

  2. Growth inhibiting activity of lipophilic extracts from Dipsacus sylvestris Huds. roots against Borrelia burgdorferi s. s. in vitro.

    Science.gov (United States)

    Liebold, T; Straubinger, R K; Rauwald, H W

    2011-08-01

    Fresh first year roots from Dipsacus sylvestris HUDS. were extracted with 70% ethanol, ethyl acetate as well as dichloromethane. Extracts were solubilized in water (lipophilic extracts with addition of polysorbate 80) and tested for their activity against Borrelia burgdorferi sensu stricto in vitro during an eight-day period using amoxicillin as standard. The hydroethanolic extract showed no growth inhibition whereas significant growth inhibiting activity could be shown in the two less polar fractions for the first time. Strongest inhibition was found in the ethyl acetate extract. The effect of polysorbate 80 on bacterial growth was examined and found to be negligible. As the nature of bioactive constituents has not been clarified yet, a micellar electrokinetic capillary chromatography fingerprint analysis for a methanolic extract was applied including loganin, chlorogenic acid, cantleyoside and caffeic acid as marker substances.

  3. Predicting Students’ Performance using Modified ID3 Algorithm

    Directory of Open Access Journals (Sweden)

    Ramanathan L

    2013-06-01

    Full Text Available The ability to predict performance of students is very crucial in our present education system. We can use data mining concepts for this purpose. ID3 algorithm is one of the famous algorithms present today to generate decision trees. But this algorithm has a shortcoming that it is inclined to attributes with many values. So , this research aims to overcome this shortcoming of the algorithm by using gain ratio(instead of information gain as well as by giving weights to each attribute at every decision making point. Several other algorithms like J48 and Naive Bayes classification algorithm are alsoapplied on the dataset. The WEKA tool was used for the analysis of J48 and Naive Bayes algorithms. The results are compared and presented. The dataset used in our study is taken from the School of Computing Sciences and Engineering (SCSE, VIT University.

  4. Forensic validation of the SNPforID 52-plex assay

    DEFF Research Database (Denmark)

    Musgrave-Brown, Esther; Ballard, David; Balogh, Kinga

    2007-01-01

    The advantages of single nucleotide polymorphism (SNP) typing in forensic genetics are well known and include a wider choice of high-throughput typing platforms, lower mutation rates, and improved analysis of degraded samples. However, if SNPs are to become a realistic supplement to current short...... tandem repeat (STR) typing methods, they must be shown to successfully and reliably analyse the challenging samples commonly encountered in casework situations. The European SNPforID consortium, supported by the EU GROWTH programme, has developed a multiplex of 52 SNPs for forensic analysis...... in forensic casework. A total of 40 extracts were used in the study, each of which was sent to two of the five participating laboratories for typing in duplicate or triplicate. Laboratories were instructed to carry out their analyses as if they were dealing with normal casework samples. Results were reported...

  5. Applying Open Researchers and Contributors ID in scholarly journals

    Directory of Open Access Journals (Sweden)

    Jeonghee Im

    2015-02-01

    Full Text Available Open Researchers and Contributors ID (ORCID launched its registry services in October 2012. Consequently, adding personal information to the ORCID registry became routine work for researchers. To add ORCID to an online article, the tag needs to be included in the Journal Article Tag Suite extensible markup language file, if such a file has been produced by the publisher. Subsequently, all co-authors’ ORCID can be easily and conveniently collected and then integrated into the manuscript management system. In the current age of information and the Internet, journals need to keep pace with the surge of new standards and technologies. Editors should be able to accept and apply these new systems rapidly.

  6. ID-Check: Online Concealed Information Test Reveals True Identity.

    Science.gov (United States)

    Verschuere, Bruno; Kleinberg, Bennett

    2016-01-01

    The Internet has already changed people's lives considerably and is likely to drastically change forensic research. We developed a web-based test to reveal concealed autobiographical information. Initial studies identified a number of conditions that affect diagnostic efficiency. By combining these moderators, this study investigated the full potential of the online ID-check. Participants (n = 101) tried to hide their identity and claimed a false identity in a reaction time-based Concealed Information Test. Half of the participants were presented with personal details (e.g., first name, last name, birthday), whereas the others only saw irrelevant details. Results showed that participants' true identity could be detected with high accuracy (AUC = 0.98; overall accuracy: 86-94%). Online memory detection can reliably and validly detect whether someone is hiding their true identity. This suggests that online memory detection might become a valuable tool for forensic applications.

  7. Improvement of the ID model for quantitative network data

    DEFF Research Database (Denmark)

    Sørensen, Peter Borgen; Damgaard, Christian Frølund; Dupont, Yoko Luise

    2015-01-01

    )1. This presentation will illustrate the application of the ID method based on a data set which consists of counts of visits by 152 pollinator species to 16 plant species. The method is based on two definitions of the underlying probabilities for each combination of pollinator and plant species: (1), pi...... reproduce the high number of zero valued cells in the data set and mimic the sampling distribution. 1 Sørensen et al, Journal of Pollination Ecology, 6(18), 2011, pp129-139......Many interactions are often poorly registered or even unobserved in empirical quantitative networks. Hence, the output of the statistical analyses may fail to differentiate between patterns that are statistical artefacts and those which are real characteristics of ecological networks...

  8. Effectiveness of Iphone’s Touch ID: KSA Case Study

    Directory of Open Access Journals (Sweden)

    Ahmad A. Al-Daraiseh

    2015-01-01

    Full Text Available A new trend of incorporating Touch ID sensors in mobile devices is appearing. Last year, Apple released a new model of its famous iPhone (5s. One of the most anticipated and hailed features of the new device was its Touch ID. Apple advertised that the new technology will increase the security of its device, and it will also be used in different applications as a proof of identity. To make the issue more controversial, Apple announced a new financial service (Apple Pay that allows iPhone 6 users to use their iPhone as a replacement to credit cards. The minute the new technology was introduced; many questions appeared that needed immediate answers. Users were concerned about how it will work? Is it easy to use? Is it really safe? And whether it will be effective in protecting their private data or not? In this paper we provide a comprehensive study of this feature. We discuss the advantages and disadvantages of using it. Then we analyze and share the results of a survey that we conducted to measure the effectiveness of such feature in the Kingdom of Saudi Arabia (KSA. In this study, we only focus on users from KSA, because if the device fails to protect mobile’s data, severe consequences might happen. Due to cultural believes in KSA, releasing mobile contents to unauthorized people could lead to crimes. Survey analysis revealed somewhat controversial results, while 76% of all participants believe that this technology will improve the device security, only 33% use it to lock/unlock their devices, and even a smaller percentage use it to make purchases.

  9. Inhibitor of differentiation 4 (Id4 is a potential tumor suppressor in prostate cancer

    Directory of Open Access Journals (Sweden)

    Carey Jason PW

    2009-06-01

    Full Text Available Abstract Background Inhibitor of differentiation 4 (Id4, a member of the Id gene family is also a dominant negative regulator of basic helix loop helix (bHLH transcription factors. Some of the functions of Id4 appear to be unique as compared to its other family members Id1, Id2 and Id3. Loss of Id4 gene expression in many cancers in association with promoter hypermethylation has led to the proposal that Id4 may act as a tumor suppressor. In this study we provide functional evidence that Id4 indeed acts as a tumor suppressor and is part of a cancer associated epigenetic re-programming. Methods Data mining was used to demonstrate Id4 expression in prostate cancer. Methylation specific polymerase chain reaction (MSP analysis was performed to understand molecular mechanisms associated with Id4 expression in prostate cancer cell lines. The effect of ectopic Id4 expression in DU145 cells was determined by cell cycle analysis (3H thymidine incorporation and FACS, expression of androgen receptor, p53 and cyclin dependent kinase inhibitors p27 and p21 by a combination of RT-PCR, real time-PCR, western blot and immuno-cytochemical analysis. Results Id4 expression was down-regulated in prostate cancer. Id4 expression was also down-regulated in prostate cancer line DU145 due to promoter hyper-methylation. Ectopic Id4 expression in DU145 prostate cancer cell line led to increased apoptosis and decreased cell proliferation due in part by an S-phase arrest. In addition to S-phase arrest, ectopic Id4 expression in PC3 cells also resulted in prolonged G2/M phase. At the molecular level these changes were associated with increased androgen receptor (AR, p21, p27 and p53 expression in DU145 cells. Conclusion The results suggest that Id4 acts directly as a tumor suppressor by influencing a hierarchy of cellular processes at multiple levels that leads to a decreased cell proliferation and change in morphology that is possibly mediated through induction of previously

  10. Characterizing and Managing Intrusion Detection System (IDS) Alerts with Multi-Server/Multi-Priority Queuing Theory

    Science.gov (United States)

    2014-12-26

    IDS called SNORT®. ( Roesch & Green, 2014) .......... 3 Figure 2. A basic queuing theory diagram calling out the six defining characteristics of a...particular format is from the popular open source IDS called SNORT®. ( Roesch & Green, 2014) The set of signatures within an IDS is called its rule-set...nicol/ece541/slides/queueing.pdf Roesch , M., & Green, C. (2014). SNORT Users Manual. Retrieved August 2014, from SNORT: http://manual.snort.org/ Saad

  11. The Implementation of C-ID, R2D2 Model on Learning Reading Comprehension

    Science.gov (United States)

    Rayanto, Yudi Hari; Rusmawan, Putu Ngurah

    2016-01-01

    The purposes of this research are to find out, (1) whether C-ID, R2D2 model is effective to be implemented on learning Reading comprehension, (2) college students' activity during the implementation of C-ID, R2D2 model on learning Reading comprehension, and 3) college students' learning achievement during the implementation of C-ID, R2D2 model on…

  12. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Science.gov (United States)

    2010-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  13. A brief review of revocable ID-based public key cryptosystem

    Directory of Open Access Journals (Sweden)

    Tsu-Yang Wu

    2016-03-01

    Full Text Available The design of ID-based cryptography has received much attention from researchers. However, how to revoke the misbehaviour/compromised user in ID-based public key cryptosystem becomes an important research issue. Recently, Tseng and Tsai proposed a novel public key cryptosystem called revocable ID-based public key cryptosystem (RIBE to solve the revocation problem. Later on, numerous research papers based on the Tseng-Tsai key RIBE were proposed. In this paper, we brief review Tseng and Tsai's RIBE. We hope this review can help the readers to understand the Tseng and Tsai's revocable ID-based public key cryptosystem.

  14. Id expression in amphioxus and lamprey highlights the role of gene cooption during neural crest evolution

    Science.gov (United States)

    Meulemans, Daniel; McCauley, David; Bronner-Fraser, Marianne

    2003-01-01

    Neural crest cells are unique to vertebrates and generate many of the adult structures that differentiate them from their closest invertebrate relatives, the cephalochordates. Id genes are robust markers of neural crest cells at all stages of development. We compared Id gene expression in amphioxus and lamprey to ask if cephalochordates deploy Id genes at the neural plate border and dorsal neural tube in a manner similar to vertebrates. Furthermore, we examined whether Id expression in these cells is a basal vertebrate trait or a derived feature of gnathostomes. We found that while expression of Id genes in the mesoderm and endoderm is conserved between amphioxus and vertebrates, expression in the lateral neural plate border and dorsal neural tube is a vertebrate novelty. Furthermore, expression of lamprey Id implies that recruitment of Id genes to these cells occurred very early in the vertebrate lineage. Based on expression in amphioxus we postulate that Id cooption conferred sensory cell progenitor-like properties upon the lateral neurectoderm, and pharyngeal mesoderm-like properties upon cranial neural crest. Amphioxus Id expression is also consistent with homology between the anterior neurectoderm of amphioxus and the presumptive placodal ectoderm of vertebrates. These observations support the idea that neural crest evolution was driven in large part by cooption of multipurpose transcriptional regulators from other tissues and cell types.

  15. Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)

    Energy Technology Data Exchange (ETDEWEB)

    Jared Verba; Michael Milvich

    2008-05-01

    Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

  16. Achieving Payoffs from an Industry Cloud Ecosystem at BankID

    DEFF Research Database (Denmark)

    Eaton, Ben; Hallingby, Hanne Kristine; Nesse, Per-Jonny

    2014-01-01

    BankID is an industry cloud owned by Norwegian banks. It provides electronic identity, authentication and electronic signing capabilities for banking, merchant and government services. More than 60% of the population uses BankID services. As the broader ecosystem around BankID evolved, challenges......—arising from tensions between different parts of the ecosystem—had to be resolved. The four lessons learned from the BankID case will help others to build an industry cloud and establish a healthy ecosystem to service a broad user base....

  17. Molecular characterization of lactobacilli isolated from fermented idli batter

    Directory of Open Access Journals (Sweden)

    Perumal Jayaprabha Agaliya

    2013-12-01

    Full Text Available Lactic acid bacteria are non pathogenic organism widely distributed in nature typically involved in a large number of spontaneous food fermentation. The purpose of this study was to characterize the bacteriocinogenic lactobacilli from fermented idli batter which can find application in biopreservation and biomedicine. Eight most promising lactobacilli were chosen from twenty two isolates based on their spectrum of activity against other lactic acid bacteria and pathogens. The eight lactobacilli were characterized based on the various classical phenotypic tests, physiological tests and biochemical tests including various carbohydrate utilization profiles. All isolates were homo fermentative, catalase, and gelatin negative. Molecular characterization was performed by RAPD, 16S rRNA analysis, 16S ARDRA, and Multiplex PCR for species identification. RAPD was carried out using the primer R2 and M13. Five different clusters were obtained based on RAPD indicating strain level variation. 16S rRNA analysis showed 99 to 100% homology towards Lactobacillus plantarum. The restriction digestion pattern was similar for all the isolates with the restriction enzyme AluI. The subspecies were identified by performing Multiplex PCR using species specific primer. Among the five clusters, three clusters were clearly identified as Lactobacillus plantarum subsp. plantarum, Lactobacillus pentosus, and Lactobacillus plantarum subsp. argentoratensis.

  18. Molecular characterization of lactobacilli isolated from fermented idli batter.

    Science.gov (United States)

    Agaliya, Perumal Jayaprabha; Jeevaratnam, Kadirvelu

    2013-12-01

    Lactic acid bacteria are non pathogenic organism widely distributed in nature typically involved in a large number of spontaneous food fermentation. The purpose of this study was to characterize the bacteriocinogenic lactobacilli from fermented idli batter which can find application in biopreservation and biomedicine. Eight most promising lactobacilli were chosen from twenty two isolates based on their spectrum of activity against other lactic acid bacteria and pathogens. The eight lactobacilli were characterized based on the various classical phenotypic tests, physiological tests and biochemical tests including various carbohydrate utilization profiles. All isolates were homo fermentative, catalase, and gelatin negative. Molecular characterization was performed by RAPD, 16S rRNA analysis, 16S ARDRA, and Multiplex PCR for species identification. RAPD was carried out using the primer R2 and M13. Five different clusters were obtained based on RAPD indicating strain level variation. 16S rRNA analysis showed 99 to 100% homology towards Lactobacillus plantarum. The restriction digestion pattern was similar for all the isolates with the restriction enzyme AluI. The subspecies were identified by performing Multiplex PCR using species specific primer. Among the five clusters, three clusters were clearly identified as Lactobacillus plantarum subsp. plantarum, Lactobacillus pentosus, and Lactobacillus plantarum subsp. argentoratensis.

  19. L’idéologie : une notion bien embarrassante

    OpenAIRE

    Dominique Maingueneau

    2007-01-01

    Je ne pense pas être la personne la mieux placée pour réfléchir sur l’intérêt que présente la notion d’idéologie pour ceux qui étudient la littérature. Le travail conceptuel sur cette notion a plutôt été le fait de la génération antérieure à la mienne. Je suppose que si l’on m’a sollicité pour en parler, c’est parce que de l’intérieur de l’analyse du discours j’ai été amené à me confronter – quoique dans un cadre théorique et méthodologique très différent – à des questions du même ordre. Fau...

  20. Generating unique IDs from patient identification data using security models

    Directory of Open Access Journals (Sweden)

    Emad A Mohammed

    2016-01-01

    Full Text Available Background: The use of electronic health records (EHRs has continued to increase within healthcare systems in the developed and developing nations. EHRs allow for increased patient safety, grant patients easier access to their medical records, and offer a wealth of data to researchers. However, various bioethical, financial, logistical, and information security considerations must be addressed while transitioning to an EHR system. The need to encrypt private patient information for data sharing is one of the foremost challenges faced by health information technology. Method: We describe the usage of the message digest-5 (MD5 and secure hashing algorithm (SHA as methods for encrypting electronic medical data. In particular, we present an application of the MD5 and SHA-1 algorithms in encrypting a composite message from private patient information. Results: The results show that the composite message can be used to create a unique one-way encrypted ID per patient record that can be used for data sharing. Conclusion: The described software tool can be used to share patient EMRs between practitioners without revealing patients identifiable data.

  1. Application of Statistical Process Control Methods for IDS

    Directory of Open Access Journals (Sweden)

    Muhammad Sadiq Ali Khan

    2012-11-01

    Full Text Available As technology improves, attackers are trying to get access to the network system resources by so many means. Open loop holes in the network allow them to penetrate in the network more easily; statistical methods have great importance in the area of computer and network security, in detecting the malfunctioning of the network system. Development of internet security solution needed to protect the system and to with stand prolonged and diverse attack. In this paper Statistical approach has been used, conventionally Statistical Control Charts has been used for quality characteristics however in IDS abnormal access can be easily detected and appropriate control limit can be established. Two different charts are investigated and Shewhart chart based on average has produced better accuracy. The approach used here for intrusion detection in such a way that if the data packet is drastically different from normal variation then it can be classified as attack. In other words a system variation may be due to some special reason. If these causes are investigated then natural variation and abnormal variation can be distinguished which can be used for distinction of behaviors of the system.

  2. L’idéologie : une notion bien embarrassante

    Directory of Open Access Journals (Sweden)

    Dominique Maingueneau

    2007-02-01

    Full Text Available Je ne pense pas être la personne la mieux placée pour réfléchir sur l’intérêt que présente la notion d’idéologie pour ceux qui étudient la littérature. Le travail conceptuel sur cette notion a plutôt été le fait de la génération antérieure à la mienne. Je suppose que si l’on m’a sollicité pour en parler, c’est parce que de l’intérieur de l’analyse du discours j’ai été amené à me confronter – quoique dans un cadre théorique et méthodologique très différent – à des questions du même ordre. Faut...

  3. Precise Location Acquisition of Mobility Data Using Cell ID

    Directory of Open Access Journals (Sweden)

    Shafqat Ali Shad

    2012-05-01

    Full Text Available Cellular network data has become a hot source of study for extraction of user-mobility and spatio-temporal trends. Location binding in mobility data can be done through different methods like GPS, service provider assisted faux-GPS and Cell Global Identity (CGI. Among these Cell Global Identity is most inexpensive method and readily available solution for mobility extraction; however exact spatial extraction is somehow a problem in it. This paper presents the spatial extraction technique of mobile phone user raw data which carries the information like location information, proximity location and activity of subjects. This work mainly focuses on the data pre-processing methodology and technique to interpret the low level mobility data into high level mobility information using the designed clustering methodology and publically available Cell-IDs databases. Work proposed the semi- supervised strategy to derive the missing locations thorough the usage of semantic tag information and removal of spatial outliers for precise mobility profile building.

  4. Efeito anti-helmíntico do hidrolato de Mentha villosa Huds. (Lamiaceae em nematóides gastrintestinais de bovinos Anthelmintic effect of hidrolact of Mentha villosa Huds. (Lamiaceae in gastrointestinal nematodes of cattle

    Directory of Open Access Journals (Sweden)

    Érica Maria Nascimento

    2009-06-01

    Full Text Available Atualmente, o estudo da atividade anti-helmíntica de plantas medicinais em ruminantes tem atraído bastante interesse. Mentha villosa Huds. (Lamiaceae é uma das espécies de hortelã que tem sido utilizada popularmente devido às diversas propriedades medicinais, inclusive para o controle de verminoses. O presente estudo teve como objetivo testar a atividade anti-helmíntica do hidrolato dessa planta em bezerras infectadas por nematóides gastrintestinais, tanto in vitro, pelo método de coprocultura quantitativa, quanto in vivo, por meio do teste de redução no número de ovos de nematóides nas fezes dos hospedeiros. No teste in vitro, o hidrolato nas concentrações de 40%, 60% e 80% e 100% apresentou porcentagem de eficácia de 91,88%, 94,15%, 98,40% e 100%, respectivamente, mostrando atividade ovicida significativa sobre nematóides gastrintestinais em bezerras. Entretanto, os resultados do teste in vivo mostraram ausência de atividade anti-helmíntica do hidrolato de M. villosa na dose de 0,1ml kg dia-1, nos animais tratados.Currently, it has been of great interest to study the anthelmintic activity of medicinal plants in ruminants. Mentha villosa Huds. (Lamiaceae is one of the mint species that has been popularly used based on various medicinal properties, even for the control of nematode infections. This study aimed to test the anthelmintic activity of hidrolact of this plant, both in vitro, by the quantitative coproculture method, and in vivo, in calves infected with gastrointestinal nematodes, through the egg count reduction test in feces of the hosts. In in vitro tests, the hidrolact at the concentrations 40%, 60% and 80% and 100% obtained percentage of effectiveness of 91.88%, 94.15%, 98.40% and 100% respectively, showing significant ovicidal activity against gastrointestinal nematodes in calves. However, the hidrolact of M. villosa showed no in vivo anthelmintic activity at 0.1ml kg-1 day-1 on the treated animals.

  5. Conventional Chiralpak ID vs. capillary Chiralpak ID-3 amylose tris-(3-chlorophenylcarbamate)-based chiral stationary phase columns for the enantioselective HPLC separation of pharmaceutical racemates.

    Science.gov (United States)

    Ahmed, Marwa; Gwairgi, Marina; Ghanem, Ashraf

    2014-11-01

    A comparative enantioselective analysis using immobilized amylose tris-(3-chlorophenylcarbamate) as chiral stationary phase in conventional high-performance liquid chromatography (HPLC) with Chiralpak ID (4.6 mm ID × 250 mm, 5 µm silica gel) and micro-HPLC with Chiralpak ID-3 (0.30 mm ID × 150 mm, 3 µm silica gel) was conducted. Pharmaceutical racemates of 12 pharmacological classes, namely, α- and β-blockers, anti-inflammatory drugs, antifungal drugs, dopamine antagonists, norepinephrine-dopamine reuptake inhibitors, catecholamines, sedative hypnotics, diuretics, antihistaminics, anticancer drugs, and antiarrhythmic drugs were screened under normal phase conditions. The effect of an organic modifier on the analyte retentions and enantiomer recognition was investigated. Baseline separation was achieved for 1-acenaphthenol, carprofen, celiprolol, cizolirtine carbinol, miconazole, tebuconazole, 4-hydroxy-3-methoxymandelic acid, 1-indanol, 1-(2-chlorophenyl)ethanol, 1-phenyl-2-propanol, flavanone, 6-hydroxyflavanone, 4-bromogluthethimide, and pentobarbital on the 4.6 mm ID packed with a 5 µm silica column using conventional HPLC. Nonetheless, baseline separation was achieved for aminoglutethimide, naftopidil, and thalidomide on the 0.3 mm ID packed with a 3 µm silica capillary column.

  6. Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.

    Directory of Open Access Journals (Sweden)

    April S Chan

    Full Text Available BACKGROUND: The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells naturally suggests that they interact with one another, but these interactions are just beginning to be characterized. METHODOLOGY/PRINCIPAL FINDINGS: An Id1(-/- mouse model was used to assess the role of Id1 in the bone marrow microenvironment. Micro-computed tomography and fracture tests showed that Id1(-/- mice have reduced bone mass and increased bone fragility, consistent with an osteoporotic phenotype. Osteoclastogenesis and pit formation assays revealed that loss of Id1 increased osteoclast differentiation and resorption activity, both in vivo and in vitro, suggesting a cell autonomous role for Id1 as a negative regulator of osteoclast differentiation. Examination by flow cytometry of the hematopoietic compartment of Id1(-/- mice showed an increase in myeloid differentiation. Additionally, we found increased expression of osteoclast genes, TRAP, Oscar, and CTSK in the Id1(-/- bone marrow microenvironment. Lastly, transplantation of wild-type bone marrow into Id1(-/- mice repressed TRAP, Oscar, and CTSK expression and activity and rescued the hematopoietic and bone phenotype in these mice. CONCLUSIONS/SIGNIFICANCE: In conclusion, we demonstrate an osteoporotic phenotype in Id1(-/- mice and a mechanism for Id1 transcriptional control of osteoclast-associated genes. Our results identify Id1 as a principal player responsible for the dynamic cross-talk between bone and bone marrow hematopoietic cells.

  7. 75 FR 22695 - Establishment of Class E Airspace; Bonners Ferry, ID

    Science.gov (United States)

    2010-04-30

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Bonners Ferry, ID AGENCY... E airspace at Bonners Ferry, ID, to accommodate aircraft using a new Area Navigation (RNAV) Global... improve the safety and management of Instrument Flight Rules (IFR) operations at the airport. DATES...

  8. The Mathematica package TopoID and its application to the Higgs boson production cross section

    Energy Technology Data Exchange (ETDEWEB)

    Hoff, Jens

    2016-07-15

    We present the Mathematica package TopoID which aims at the automation of several steps in multiloop calculations. The algorithm which lies at the very core of the package is described and illustrated with an example. The main features of TopoID are stated and some of them are briefly demonstrated for NLO or NNLO Higgs boson production.

  9. Id2a is required for hepatic outgrowth during liver development in zebrafish.

    Science.gov (United States)

    Khaliq, Mehwish; Choi, Tae-Young; So, Juhoon; Shin, Donghun

    2015-11-01

    During development, inhibitor of DNA binding (Id) proteins, a subclass of the helix-loop-helix family of proteins, regulate cellular proliferation, differentiation, and apoptosis in various organs. However, a functional role of Id2a in liver development has not yet been reported. Here, using zebrafish as a model organism, we provide in vivo evidence that Id2a regulates hepatoblast proliferation and cell death during liver development. Initially, in the liver, id2a is expressed in hepatoblasts and after their differentiation, id2a expression is restricted to biliary epithelial cells. id2a knockdown in zebrafish embryos had no effect on hepatoblast specification or hepatocyte differentiation. However, liver size was greatly reduced in id2a morpholino-injected embryos, indicative of a hepatic outgrowth defect attributable to the significant decrease in proliferating hepatoblasts concomitant with the significant increase in hepatoblast cell death. Altogether, these data support the role of Id2a as an important regulator of hepatic outgrowth via modulation of hepatoblast proliferation and survival during liver development in zebrafish.

  10. Manual of spIds, a software package for parameter identification in dynamic systems

    NARCIS (Netherlands)

    Everaars, C.T.H.; Hemker, P.W.; Stortelder, W.J.H.

    1995-01-01

    This report contains the manual of spIds, version 1.0, a software package for parameter identification in dynamic systems. SpIdslabel{ab:spIds is an acronym of underline{simulation and underline{parameter underline{identification in underline{dynamic underline {systems. It can be applied on wide var

  11. 81 FR 16198 - Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and Washington Counties, ID, and...

    Science.gov (United States)

    2016-03-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Fish and Wildlife Service Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and Washington..., 1010 Dearborn St., Caldwell, ID 83605. Homedale Public Library, 125 W Owyhee Ave., Homedale, ID...

  12. 75 FR 41232 - Deer Flat National Wildlife Refuge, Canyon, Owyhee, Payette, and Washington Counties, ID; Malheur...

    Science.gov (United States)

    2010-07-15

    ... Fish and Wildlife Service Deer Flat National Wildlife Refuge, Canyon, Owyhee, Payette, and Washington...). The Refuge has units located in Canyon, Owyhee, Payette, and Washington Counties, ID, and Malheur... the Snake River located in Canyon, Payette, Owyhee, and Washington Counties in ID; and Malheur...

  13. Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

    DEFF Research Database (Denmark)

    Gibbs-Seymour, Ian; Oka, Yasuyoshi; Rajendra, Eeson

    2015-01-01

    We show that central components of the Fanconi anemia (FA) DNA repair pathway, the tumor suppressor proteins FANCI and FANCD2 (the ID complex), are SUMOylated in response to replication fork stalling. The ID complex is SUMOylated in a manner that depends on the ATR kinase, the FA ubiquitin ligase...

  14. 75 FR 47515 - Identification (ID) Cards for Members of the Uniformed Services, Their Dependents, and Other...

    Science.gov (United States)

    2010-08-06

    ... Services, Their Dependents, and Other Eligible Individuals AGENCY: Office of the Under Secretary of Defense... DoD ID cards. The ID cards shall be issued to uniformed service members, their dependents, and other.... The general policy for comments and other submissions from members of the public is to make...

  15. Wicked ID: Conceptual Framework for Considering Instructional Design as a Wicked Problem

    Science.gov (United States)

    Becker, Katrin

    2007-01-01

    The process of instructional design has parallels in other design disciplines. Software design is one that has experienced intense attention in the last 30 or so years, and many lessons learned there can be applied to ID. Using software design as a springboard, this concept paper seeks to propose a new approach to ID. It suggests that…

  16. The ID23-2 structural biology microfocus beamline at the ESRF

    Energy Technology Data Exchange (ETDEWEB)

    Flot, David, E-mail: flot@esrf.fr [European Molecular Biology Laboratory, 6 rue Jules Horowitz, BP 181, 38042 Grenoble (France); Mairs, Trevor; Giraud, Thierry; Guijarro, Matias; Lesourd, Marc; Rey, Vicente; Brussel, Denis van; Morawe, Christian; Borel, Christine; Hignette, Olivier; Chavanne, Joel; Nurizzo, Didier; McSweeney, Sean; Mitchell, Edward [European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 181, 38043 Grenoble (France)

    2010-01-01

    Beamline ID23-2, the first dedicated and highly automated high-throughput monochromatic macromolecular crystallography microfocus beamline, is described. The first phase of the ESRF beamline ID23 to be constructed was ID23-1, a tunable MAD-capable beamline which opened to users in early 2004. The second phase of the beamline to be constructed is ID23-2, a monochromatic microfocus beamline dedicated to macromolecular crystallography experiments. Beamline ID23-2 makes use of well characterized optical elements: a single-bounce silicon (111) monochromator and two mirrors in Kirkpatrick–Baez geometry to focus the X-ray beam. A major design goal of the ID23-2 beamline is to provide a reliable, easy-to-use and routine microfocus beam. ID23-2 started operation in November 2005, as the first beamline dedicated to microfocus macromolecular crystallography. The beamline has taken the standard automated ESRF macromolecular crystallography environment (both hardware and software), allowing users of ID23-2 to be rapidly familiar with the microfocus environment. This paper describes the beamline design, the special considerations taken into account given the microfocus beam, and summarizes the results of the first years of the beamline operation.

  17. Extending the Intermediate Data Structure (IDS for longitudinal historical databases to include geographic data

    Directory of Open Access Journals (Sweden)

    Finn Hedefalk

    2014-09-01

    Full Text Available The Intermediate Data Structure (IDS is a standardised database structure for longitudinal historical databases. Such a common structure facilitates data sharing and comparative research. In this study, we propose an extended version of IDS, named IDS-Geo, that also includes geographic data. The geographic data that will be stored in IDS-Geo are primarily buildings and/or property units, and the purpose of these geographic data is mainly to link individuals to places in space. When we want to assign such detailed spatial locations to individuals (in times before there were any detailed house addresses available, we often have to create tailored geographic datasets. In those cases, there are benefits of storing geographic data in the same structure as the demographic data. Moreover, we propose the export of data from IDS-Geo using an eXtensible Markup Language (XML Schema. IDS-Geo is implemented in a case study using historical property units, for the period 1804 to 1913, stored in a geographically extended version of the Scanian Economic Demographic Database (SEDD. To fit into the IDS-Geo data structure, we included an object lifeline representation of all of the property units (based on the snapshot time representation of single historical maps and poll-tax registers. The case study verifies that the IDS-Geo model is capable of handling geographic data that can be linked to demographic data.

  18. Sexual abuse involving children with an intellectual disability (ID): a narrative review

    NARCIS (Netherlands)

    Wissink, I.B.; van Vugt, E.S.; Moonen, X.; Stams, G.J.J.M.; Hendriks, J.

    2015-01-01

    The current paper provides a narrative review of the literature on sexual abuse, involving children with Intellectual Disability (ID). The thirteen articles that were found and met our criteria vary in their definitions of sexual abuse and in how ID was determined. Still, they do paint a general pic

  19. Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis.

    Science.gov (United States)

    Shin, Dong-Hui; Park, Ji-Hye; Lee, Jeong-Yeon; Won, Hee-Young; Jang, Ki-Seok; Min, Kyueng-Whan; Jang, Si-Hyong; Woo, Jong-Kyu; Oh, Seung Hyun; Kong, Gu

    2015-07-10

    Inhibitor of differentiation/DNA binding (Id)1 is a crucial regulator of mammary development and breast cancer progression. However, its effect on stemness and tumorigenesis in mammary epithelial cells remains undefined. Herein, we demonstrate that Id1 induces mammary tumorigenesis by increasing normal and malignant mammary stem cell (MaSC) activities in transgenic mice. MaSC-enriched basal cell expansion and increased self-renewal and in vivo regenerative capacity of MaSCs are observed in the mammary glands of MMTV-Id1 transgenic mice. Furthermore, MMTV-Id1 mice develop ductal hyperplasia and mammary tumors with highly expressed basal markers. Id1 also increases breast cancer stem cell (CSC) population and activity in human breast cancer lines. Moreover, the effects of Id1 on normal and malignant stem cell activities are mediated by the Wnt/c-Myc pathway. Collectively, these findings provide in vivo genetic evidence of Id1 functions as an oncogene in breast cancer and indicate that Id1 regulates mammary basal stem cells by activating the Wnt/c-Myc pathway, thereby contributing to breast tumor development.

  20. Cloning and shake flask expression of hrIDS-Like in Pichia pastoris

    African Journals Online (AJOL)

    STORAGESEVER

    2009-06-17

    Jun 17, 2009 ... characterized by a wide spectrum of clinical manifesta- tions, ranging from mild to ... The native IDS processing has been studied after .... the membrane was incubated overnight with a monoclonal antibody anti-IDS (1:250 in ...

  1. Rethinking Social Network Assessment for Students with Intellectual Disabilities (ID) in Postsecondary Education

    Science.gov (United States)

    Eisenman, Laura T.; Farley-Ripple, Elizabeth; Culnane, Mary; Freedman, Brian

    2013-01-01

    Social networks of persons with intellectual disabilities (ID) have been characterized as smaller and less diverse than those of typical peers. Advocates have focused on strengthening those social networks by expanding circles of social support, protection, and friendship. As young adults with ID experience increasing levels of community…

  2. Clarté des idées innées ?

    DEFF Research Database (Denmark)

    Schøsler, Jørn

    2013-01-01

    Der gives en analyse af begreberne 'evidens' og 'medfødte idéer' hos Descartes og Locke samt hos de franske oplysningsfilosoffer.......Der gives en analyse af begreberne 'evidens' og 'medfødte idéer' hos Descartes og Locke samt hos de franske oplysningsfilosoffer....

  3. 76 FR 9266 - Proposed Amendment of Class D and Class E Airspace; Idaho Falls, ID

    Science.gov (United States)

    2011-02-17

    ... Falls, ID AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend the Class D and Class E airspace areas at Idaho Falls, ID, by changing the name of the airport to Idaho Falls Regional Airport, and adjusting the...

  4. 76 FR 28306 - Amendment of Class D and Class E Airspace; Idaho Falls, ID

    Science.gov (United States)

    2011-05-17

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class D and Class E Airspace; Idaho Falls, ID... existing Class D and Class E airspace at Idaho Falls, ID, by changing the name of the airport to Idaho Falls Regional Airport, and adjusting the geographic coordinates of the airport. This action also...

  5. 78 FR 25406 - Proposed Modification of Class E Airspace; Twin Falls, ID

    Science.gov (United States)

    2013-05-01

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of Class E Airspace; Twin Falls, ID...: This action proposes to modify Class E airspace at Twin Falls Joslin Field-Magic Valley Regional Airport, Twin Falls, ID. Controlled airspace is necessary to accommodate aircraft using the...

  6. 78 FR 40382 - Modification of Class D and E Airspace; Twin Falls, ID

    Science.gov (United States)

    2013-07-05

    ... Federal Aviation Administration 14 CFR Part 71 Modification of Class D and E Airspace; Twin Falls, ID... Class E airspace at Twin Falls Joslin Field-Magic Valley Regional Airport, Twin Falls, ID, to... areas, as well as corrects the airport name to Twin Falls Joslin Field-Magic Valley Regional...

  7. 77 FR 56241 - Board Meeting; October 17, 2012; Idaho Falls, ID

    Science.gov (United States)

    2012-09-12

    ... REVIEW BOARD Board Meeting; October 17, 2012; Idaho Falls, ID The U.S. Nuclear Waste Technical Review... 1987, the U.S. Nuclear Waste Technical Review Board will hold a public meeting in Idaho Falls, Idaho... Board meeting will be held at the Hilton Garden Inn, 700 Lindsay Boulevard, Idaho Falls, ID 83402;...

  8. Long-range optical character recognition for product ID

    Science.gov (United States)

    Banta, Larry E.; Pertl, Franz A.; Rosenberry-Friend, Kimberly A.

    1998-10-01

    An automated product tag reading system based on CCD cameras and computer image processing has been developed by West Virginia University and demonstrated at the Weirton Steel Corporation. The system reads both a 50-mil barcode and a string of six numbers on a four-inch by six-inch tag fastened to the end of a steel slab. Feedback from the image is used to point and zoom the camera, making the system effective at ranges up to thirty feet, and in bright sunlight-situations where handheld barcode scanners are ineffective. A video camera is mounted on a pan/tilt head and connected to a personal computer through a frame grabber board. The whole system is mounted on a slab hauler--a huge wheeled machine for carrying 100 tons of steel slabs at a time. The slab hauler backs into position and presses `start' on a touchscreen operator interface. A wide-angle image is grabbed, and the computer analyzes the images to find product ID tags in scene. The camera is then zoomed and pointed one-by-one at the tags for closeup images. Geometric warping is done on the closeup images to correct for viewing angle distortion, and both the barcode and the alphanumeric code are read by the software and reported to the inventory management system via radio modern. This paper discusses the neural network-based system for reading the characters on the tag. The camera pointing system and barcode reader are discussed in a companion paper.

  9. ID-based authentication scheme combined with identity-based encryption with fingerprint hashing

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Current identity-based (ID) cryptosystem lacks the mechanisms of two-party authentication and user's private key distribution. Some ID-based signcryption schemes and ID-based authenticated key agreement protocols have been presented, but they cannot solve the problem completely. A novel ID-based authentication scheme based on ID-based encryption (IBE) and fingerprint hashing method is proposed to solve the difficulties in the IBE scheme, which includes message receiver authenticating the sender, the trusted authority (TA) authenticating the users and transmitting the private key to them. Furthermore, the scheme extends the application of fingerprint authentication from terminal to network and protects against fingerprint data fabrication. The fingerprint authentication method consists of two factors. This method combines a token key, for example, the USB key, with the user's fingerprint hash by mixing a pseudo-random number with the fingerprint feature. The security and experimental efficiency meet the requirements of practical applications.

  10. ID3算法在汽车售后服务中的应用%Application of ID3 Algorithm in Automotive After-sale Service

    Institute of Scientific and Technical Information of China (English)

    郭春丽; 李明东; 赵刚

    2011-01-01

    Decision tree algorithm has been successfully applied in much classification issue.ID3 algorithm is the representative algorithm.The application of algorithm has been given an instance study for the analysis of the customer features in the automotive after-sale service.Describing the principle and implementation of the ID3 algorithm and analyzing the features of the clients,also explaining concretely the approach of how to use ID3 to manage the clients in the automotive after-sale service.At the end,setting up the customer characteristics analysis model of automotive after-sale services.Through those strategies,the companies can realize the maximization of their total profits.%决策树算法被成功应用到很多分类问题上,其中ID3算法是其典型算法.文中就该算法在汽车售后服务企业客户特征分析中的应用做了实例研究.阐述了ID3算法的原理以及实现算法,分析了客户的特征.以一个具体的案例讲解了ID3算法在汽车售后服务企业中客户管理的具体应用流程.文中实现ID3算法作用于汽车售后客户的数据,得到一个客户特征分析模型,可以帮助汽车企业根据不同特征的客户采取不同的策略,从而获得较大利润.

  11. Id-1 promotes osteosarcoma cell growth and inhibits cell apoptosis via PI3K/AKT signaling pathway

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Liang; Liao, Qi; Tang, Qiang [Department of Orthopaedic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang 300006 (China); Deng, Huan [Department of Pathology, The Fourth Affiliated Hospital of Nanchang University, Nanchang 330006 (China); Chen, Lu, E-mail: chenlu0578@163.com [Department of Orthopaedic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang 300006 (China)

    2016-02-12

    Accumulating evidence reveals that Id-1 is upregulated and functions as a potential tumor promoter in several human cancer types. However, the role of Id-1 in osteosarcoma (OS) is unknown. In present study, we found that Id-1 expression was elevated in OS tissues than adjacent normal bone tissues. More importantly, we demonstrated that overexpression of Id-1 is significantly correlated with tumor progression and poor survival in OS patients. Furthermore, increased expression of Id-1 was observed in OS cell lines and ectopic expression of Id-1 significantly enhanced in vitro cell proliferation and promoted in vivo tumor growth, whereas knockdown of Id-1 suppressed OS cells growth. Moreover, our experimental data revealed that Id-1 promotes cell proliferation by facilitating cell cycle progression and inhibits cell apoptosis. Mechanistically, the effects of Id-1 in OS cells is at least partly through activation of PI3K/Akt signaling pathway. Therefore, we identified a tumorigenic role of Id-1 in OS and suggested a potential therapeutic target for OS patients. - Highlights: • Id-1 expression is positively correlated in OS patients with poor prognosis. • Overexpression of Id-1 promotes OS cell growth in vitro and in vivo. • Id-1induces cell cycle progression and inhibits cell apoptosis. • PI3K/Akt signaling pathway contributed to the oncogenic effects of Id-1 in OS cells.

  12. Bio-fortification and shelf-life extension of idli batter using curry leaves (Murraya koenigii).

    Science.gov (United States)

    Chelliah, R; Ramakrishnan, S R; Premkumar, D; Antony, U

    2016-06-01

    Among several traditional foods of India, idli is one of the most popular and commonly consumed steamed products. A new method of adding Murraya koenigii (curry leaves) to idli batter as a vehicle for fortification and extension of shelf-life has been developed. Dried curry leaves powder was incorporated with other ingredients like rice and dehusked black gram in different proportions to optimize the most palatable formulation. Rate of fermentation and microbial changes in the batter; nutritional qualities, texture and sensory properties of the prepared product were assessed. Incorporation of curry leaves powder (5 %) in idli batter increased the shelf-life and also increased the flavour, texture and appearance of the idli. The calcium content of the prepared idli was 10 times more than that of the control idli, while dietary fiber content increased by 18.6 %. Anti-microbial activity of the curry leaves in idli batter extended the shelf-life from 2 to 5 days when stored at 30 °C.

  13. Smad3 mediates immediate early induction of Id1 by TGF-β

    Institute of Scientific and Technical Information of China (English)

    Yao-Yun Liang; F Charles Brunicardi; Xia Lin

    2009-01-01

    Id1 is a member of the inhibitor of diflferentiation(Id) protein family that regulates a wide range of cell functions.Previous studies have shown that expression of the ID1 gene is down-regulated by TGF-β in epithelial cells,whereas it is up-regulated by BMP in a variety of cell types.During our study of the biological function of TGF-β1,we found that ldl can be strongly up-regulated by TGF-β1 in the human mammary gland epithelial cell line MCF10A.Quanti-taftve real-time RT-PCR has revealed as high as 7.5-fold induction of ID1 mRNA by TGF-β1 in MCFlOA cells after 1 h of TGF-β1 stimulation,and this induction does not require de novo protein synthesis.Using Smad knockdown and knockout approaches.we have identiffed Smad3 as the responsible R-Smad for mediating transcriptional activation of the Id1 gene.Chromatin immunoprecipitation assay confirms that Smad3 and Smad4 bind to the upstream region of the Id1 gene.Our resuIts demonstrate that Smad3,but not Smad2,mediates TGF-β1-dependent early transcrip-tional induction of Id1.

  14. Id1 restrains p21 expression to control endothelial progenitor cell formation.

    Directory of Open Access Journals (Sweden)

    Alessia Ciarrocchi

    Full Text Available Loss of Id1 in the bone marrow (BM severely impairs tumor angiogenesis resulting in significant inhibition of tumor growth. This phenotype has been associated with the absence of circulating endothelial progenitor cells (EPCs in the peripheral blood of Id1 mutant mice. However, the manner in which Id1 loss in the BM controls EPC generation or mobilization is largely unknown. Using genetically modified mouse models we demonstrate here that the generation of EPCs in the BM depends on the ability of Id1 to restrain the expression of its target gene p21. Through a series of cellular and functional studies we show that the increased myeloid commitment of BM stem cells and the absence of EPCs in Id1 knockout mice are associated with elevated p21 expression. Genetic ablation of p21 rescues the EPC population in the Id1 null animals, re-establishing functional BM-derived angiogenesis and restoring normal tumor growth. These results demonstrate that the restraint of p21 expression by Id1 is one key element of its activity in facilitating the generation of EPCs in the BM and highlight the critical role these cells play in tumor angiogenesis.

  15. Engagement of membrane immunoglobulin enhances Id3 promoter activity in WEHI-231 B lymphoma cells

    Institute of Scientific and Technical Information of China (English)

    Xiao-jun LI; Kikumi HATA; Junichiro MIZUGUCHI

    2005-01-01

    Aim: We have recently shown that engagement of membrane immunoglobulin (mIg) induced upregulation of inhibitor of differentiation 3 (Id3) mRNA, resulting in growth arrest at G1 phase in WEHI-231 cells. In the present study, we examined whether engagement of mIg will affect promoter activity of the Id3 gene in WEHI231 cells. Methods: DNA fragments corresponding to the 5′-flanking region of mId3 gene were amplified by polymerase chain reaction (PCR) using genomic DNA as the template. Three DNA fragments upstream of the transcription start site (+ 1) of the mId3 gene were subcloned into the luciferase reporter vector PGVB2. The recombinant constructs were transiently transfected into WEHI-231 cells by an electroporation method. After incubation for 24 h, WEHI-231 cells were stimulated with 10 mg/L anti-IgM or irradiated CD40L-expressing NIH3T3 cells or control NIH3T3 cells for further 24 h, followed by assay for luciferase activity. Results: The luciferase analysis demonstrated that basal promoter activity of the Id3 gene was found in the region between -200 and +54. The Id3 promoter activity was increased 2-fold following stimulation with anti-IgM, but not CD40L, compared with medium alone. Conclusion: The mIg-mediated upregulation of Id3 expression is controlled, at least in part, through transcriptional regulation, as assessed by luciferase assay.

  16. An Improved ID3 Decision Tree Mining Algorithm%一种改进 ID3型决策树挖掘算法

    Institute of Scientific and Technical Information of China (English)

    潘大胜; 屈迟文

    2016-01-01

    By analyzing the problem of ID3 decision tree mining algorithm,the entropy calculation process is improved, and a kind of improved ID3 decision tree mining algorithm is built.Entropy calculation process of decision tree is rede-signed in order to obtain global optimal mining results.The mining experiments are carried out on the UCI data category 6 data set.Experimental results show that the improved mining algorithm is much better than the ID3 type decision tree mining algorithm in the compact degree and the accuracy of the decision tree construction.%分析经典 ID3型决策树挖掘算法中存在的问题,对其熵值计算过程进行改进,构建一种改进的 ID3型决策树挖掘算法。重新设计决策树构建中的熵值计算过程,以获得具有全局最优的挖掘结果,并针对 UCI 数据集中的6类数据集展开挖掘实验。结果表明:改进后的挖掘算法在决策树构建的简洁程度和挖掘精度上,都明显优于 ID3型决策树挖掘算法。

  17. Improvement and analysis of ID3 algorithm in decision-making tree

    Science.gov (United States)

    Xie, Xiao-Lan; Long, Zhen; Liao, Wen-Qi

    2015-12-01

    For the cooperative system under development, it needs to use the spatial analysis and relative technology concerning data mining in order to carry out the detection of the subject conflict and redundancy, while the ID3 algorithm is an important data mining. Due to the traditional ID3 algorithm in the decision-making tree towards the log part is rather complicated, this paper obtained a new computational formula of information gain through the optimization of algorithm of the log part. During the experiment contrast and theoretical analysis, it is found that IID3 (Improved ID3 Algorithm) algorithm owns higher calculation efficiency and accuracy and thus worth popularizing.

  18. The paradox of IDs: an account of an ethnographic experience in the US

    Directory of Open Access Journals (Sweden)

    Mariza Peirano

    2008-01-01

    Full Text Available In the modern world, IDs are indispensable objects, without which we cannot prove that we are who we say we are. We need material substantiation that attests to the authenticity of our self-identification. This paper is an account of an ethnographic experience about IDs and identification processes in the US, based on the examination of two events in which Eliot Spitzer, the New York State governor from January 2007 to March 2008, was a central figure. A comparison with the Brazilian scenario is present throughout the paper, and it ends by focusing on the ID theft phenomenon.

  19. 62 FR 28104 - Union Pacific Railroad CompanyAbandonment Exemptionin Malheur County, OR and Owyhee County, ID...

    Science.gov (United States)

    1997-05-22

    ... and Owyhee County, ID (Homedale Branch) On May 2, 1997, Union Pacific Railroad Company (UP) filed with..., and Owyhee County, ID, and includes the non-agency stations of Napton, OR-- milepost 16.90;...

  20. The treatable intellectual disability APP www.treatable-id.org: a digital tool to enhance diagnosis & care for rare diseases

    National Research Council Canada - National Science Library

    van Karnebeek, Clara D M; Houben, Roderick F A; Lafek, Mirafe; Giannasi, Wynona; Stockler, Sylvia

    2012-01-01

    .... Freely available as a WebAPP via http://www.treatable-id.org and end 2012 via the APP store, this diagnostic tool is designed for all specialists evaluating children with global delay / ID and laboratory scientists...

  1. Id-1 gene and gene products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    Science.gov (United States)

    Desprez, Pierre-Yves; Campisi, Judith

    2014-08-19

    A method for treatment of breast cancer and other types of cancer. The method comprises targeting and modulating Id-1 gene expression, if any, for the Id-1 gene, or gene products in breast or other epithelial cancers in a patient by delivering products that modulate Id-1 gene expression. When expressed, Id-1 gene is a prognostic indicator that cancer cells are invasive and metastatic.

  2. Toward operation of series IDs at BL43LXU of SPring-8

    Energy Technology Data Exchange (ETDEWEB)

    Baron, A. Q. R.; Tanaka, T.; Soutome, K.; Takao, M.; Nakamura, T.; Kobayashi, K.; Fujita, T.; Takahashi, S.; Aoyagi, H.; Shimosaki, Y.; Seike, T.; Uchiyama, H.; Ishikawa, D.; Chuang, T.-H.; Kimura, H.; Tanaka, H.; Kitamura, H.; Ishikawa, T. [SPring-8, 1-1-1 Kouto, Sayo, Hyogo, 679 (Japan)

    2016-07-27

    This paper discusses two issues relating to using 3 small gap insertion devices in series at BL43LXU of SPring-8 to make a uniquely powerful source in the 15-26 keV region of the x-ray spectrum. The issues discussed are (1) damage to the covers of the downstream IDs by radiation from the upstream IDs and (2) proper steering of the electron beam to get the best photon beam properties. After tests in several configurations, including one where an ID was run without an impedance-reducing cover, the damage issue was solved by installing a distributed absorber in the most downstream ID. The steering issues were mostly resolved by the introduction of appropriate corrector magnets and feedback. The paper is written from the viewpoint of an interested beamline scientist impressed with the cooperation of different groups to make a source for new science possible.

  3. ID migraine questionnaire in temporomandibular disorders with craniofacial pain: a study by using a multidisciplinary approach.

    Science.gov (United States)

    Di Paolo, Carlo; Di Nunno, Anna; Vanacore, Nicola; Bruti, Gianluca

    2009-08-01

    To evaluate the prevalence of migraine and related disability and the role of ID migraine questionnaire as a screening tool in patients with temporomandibular disorders (TMDs) and craniofacial pain (CFP). TMDs patients with CFP underwent stomatognathic (RDC/TMD criteria) and neurological visits (IHS criteria, 2004). ID migraine questionnaire and MIgraine Disability Assessment Scale (MIDAS) were also administered. Out of 45 patients, 69% met diagnosis of migraine plus chronic tension-type headache (CTTH); 9% presented CTTH and 20% were migraineurs. Out of 39 migraineurs who completed MIDAS, 56% presented the highest disability grade. Out of 37 patients who completed ID migraine questionnaire, 32 resulted affected by probable migraine with a diagnostic sensibility and specificity of 94% and 100%, respectively. Our findings showed a clinical association between TMDs and migraine. We support a clinical role of ID migraine and MIDAS in TMDs patients with CFP and we underline the importance of a multidisciplinary evaluation in this group of migraineurs.

  4. 80 FR 9279 - Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and Washington Counties, ID, and...

    Science.gov (United States)

    2015-02-20

    ...-2013-N279; 1265-0000-10137-S3] Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and..., 1010 Dearborn St, Caldwell, ID 83605. [ssquf] Homedale Public Library, 125 W Owyhee Ave, Homedale,...

  5. 76 FR 78940 - Minidoka National Wildlife Refuge, Blaine, Cassia, Minidoka, and Power Counties, ID...

    Science.gov (United States)

    2011-12-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Fish and Wildlife Service Minidoka National Wildlife Refuge, Blaine, Cassia, Minidoka, and Power Counties, ID; Comprehensive Conservation Plan and Environmental Assessment AGENCY: Fish and...

  6. 78 FR 773 - Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS...

    Science.gov (United States)

    2013-01-04

    ... Employment and Training Administration Hartford Financial Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial Reporting Group, Hartford, CT; Notice of Affirmative... workers of Hartford Financial Services Group, Inc., Commercial/ Actuarial/Information Delivery...

  7. Infant-directed speech (IDS) vowel clarity and child language outcomes.

    Science.gov (United States)

    Hartman, Kelly M; Ratner, Nan Bernstein; Newman, Rochelle S

    2017-09-01

    There have been many studies examining the differences between infant-directed speech (IDS) and adult-directed speech (ADS). However, investigations asking whether mothers clarify vowel articulation in IDS have reached equivocal findings. Moreover, it is unclear whether maternal speech clarification has any effect on a child's developing language skills. This study examined vowel clarification in mothers' IDS at 0;10-11, 1;6, and 2;0, as compared to their vowel production in ADS. Relationships between vowel space, vowel duration, and vowel variability and child language outcomes at two years were also explored. Results show that vowel space and vowel duration tended to be greater in IDS than in ADS, and that one measure of vowel clarity, a mother's vowel space at 1;6, was significantly related to receptive as well as expressive child language outcomes at two years of age.

  8. The Evolution of IDS Solutions in Wireless Ad-Hoc Networks To Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Novarun Deb

    2011-12-01

    Full Text Available The domain of wireless networks is inherently vulnerable to attacks due to the unreliable wireless medium. Such networks can be secured from intrusions using either prevention or detection schemes. This paper focuses its study on intrusion detection rather than prevention of attacks. As attackers keep onimprovising too, an active prevention method alone cannot provide total security to the system. Here in lies the importance of intrusion detection systems (IDS that are solely designed to detect intrusions in real time. Wireless networks are broadly classified into Wireless Ad-hoc Networks (WAHNs, Mobile Adhoc Networks (MANETs, Wireless Sensor Networks (WSNs and the most recent Wireless Mesh Networks (WMNs. Several IDS solutions have been proposed for these networks. This paper is an extension to a survey of IDS solutions for MANETs and WMNs published earlier in the sense that the present survey offers a comparative insight of recent IDS solutions for all the sub domains of wireless networks.

  9. Family Impact in Intellectual Disability, Severe Mental Health Disorders and Mental Health Disorders in ID. A Comparison

    Science.gov (United States)

    Martorell, Almudena; Gutierrez-Recacha, Pedro; Irazabal, Marcia; Marsa, Ferran; Garcia, Mercedes

    2011-01-01

    Family impact (or family burden) is a concept born in the field of mental health that has successfully been exported to the ambit of intellectual disability (ID). However, differences in family impact associated with severe mental health disorders (schizophrenia), to ID or to mental health problems in ID should be expected. Seventy-two adults with…

  10. 6 CFR 37.5 - Validity periods and deadlines for REAL ID driver's licenses and identification cards.

    Science.gov (United States)

    2010-01-01

    ... SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS General § 37.5 Validity periods and deadlines for REAL ID driver's licenses and identification cards. (a) Driver's... individuals born after December 1, 1964, unless such license or card is a REAL ID-compliant driver's...

  11. Improved D-IDS using the federated peer-to-peer architecture

    Institute of Scientific and Technical Information of China (English)

    Hoan Kyu Lee; In Joo Jang; Hyeong Seon Yoo

    2007-01-01

    A number of IDSs have been proposed for a networked or distributed environment. A modified D-IDS using federated peer-to-peer architecture, MCR (Multicast Reflector) and modified shaker protocol were proposed. The suggested scheme can be implemented easily and performs the information sharing between low-level IDS agents. As all users within a group monitor each other's, the common control server can perform detect intrusions with less cost and support the detection of the inside intruders.

  12. Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis

    OpenAIRE

    Shin, Dong-Hui; Park, Ji-Hye; Lee, Jeong-Yeon; Won, Hee-Young; Jang, Ki-Seok; MIN, KYUENG-WHAN; Jang, Si-Hyong; Woo, Jong-Kyu; Oh, Seung Hyun; Kong, Gu

    2015-01-01

    Inhibitor of differentiation/DNA binding (Id)1 is a crucial regulator of mammary development and breast cancer progression. However, its effect on stemness and tumorigenesis in mammary epithelial cells remains undefined. Herein, we demonstrate that Id1 induces mammary tumorigenesis by increasing normal and malignant mammary stem cell (MaSC) activities in transgenic mice. MaSC-enriched basal cell expansion and increased self-renewal and in vivo regenerative capacity of MaSCs are observed in th...

  13. ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy

    DEFF Research Database (Denmark)

    Rai, Taranjit Singh; Dhandapany, Perundurai Subramaniam; Ahluwalia, Tarun Veer Singh

    2008-01-01

    The study was carried to determine the association of angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with the risk of hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and restrictive cardiomyopathy (RCM).......The study was carried to determine the association of angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism with the risk of hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and restrictive cardiomyopathy (RCM)....

  14. Protection against Mycobacterium leprae infection by the ID83/GLA-SE and ID93/GLA-SE vaccines developed for tuberculosis.

    Science.gov (United States)

    Duthie, Malcolm S; Coler, Rhea N; Laurance, John D; Sampaio, Lucas H; Oliveira, Regiane M; Sousa, Ana Lucia M; Stefani, Mariane M A; Maeda, Yumi; Matsuoka, Masanori; Makino, Masahiko; Reed, Steven G

    2014-09-01

    Despite the dramatic reduction in the number of leprosy cases worldwide in the 1990s, transmission of the causative agent, Mycobacterium leprae, is still occurring, and new cases continue to appear. New strategies are required in the pursuit of leprosy elimination. The cross-application of vaccines in development for tuberculosis may lead to tools applicable to elimination of leprosy. In this report, we demonstrate that the chimeric fusion proteins ID83 and ID93, developed as antigens for tuberculosis (TB) vaccine candidates, elicited gamma interferon (IFN-γ) responses from both TB and paucibacillary (PB) leprosy patients and from healthy household contacts of multibacillary (MB) patients (HHC) but not from nonexposed healthy controls. Immunization of mice with either protein formulated with a Toll-like receptor 4 ligand (TLR4L)-containing adjuvant (glucopyranosyl lipid adjuvant in a stable emulsion [GLA-SE]) stimulated antigen-specific IFN-γ secretion from pluripotent Th1 cells. When immunized mice were experimentally infected with M. leprae, both cellular infiltration into the local lymph node and bacterial growth at the site were reduced relative to those of unimmunized mice. Thus, the use of the Mycobacterium tuberculosis candidate vaccines ID83/GLA-SE and ID93/GLA-SE may confer cross-protection against M. leprae infection. Our data suggest these vaccines could potentially be used as an additional control measure for leprosy. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  15. Id2 controls specification of Lgr5(+) intestinal stem cell progenitors during gut development.

    Science.gov (United States)

    Nigmatullina, Lira; Norkin, Maxim; Dzama, Margarita M; Messner, Berith; Sayols, Sergi; Soshnikova, Natalia

    2017-04-03

    The adult intestinal stem cells (ISCs), their hierarchies, mechanisms of maintenance and differentiation have been extensively studied. However, when and how ISCs are established during embryogenesis remains unknown. We show here that the transcription regulator Id2 controls the specification of embryonic Lgr5(+) progenitors in the developing murine small intestine. Cell fate mapping analysis revealed that Lgr5(+) progenitors emerge at E13.5 in wild-type embryos and differ from the rest on the intestinal epithelium by a characteristic ISC signature. In the absence of Id2, the intestinal epithelium differentiates into Lgr5(+) cells already at E9.5. Furthermore, the size of the Lgr5(+) cell pool is significantly increased. We show that Id2 restricts the activity of the Wnt signalling pathway at early stages and prevents precocious differentiation of the embryonic intestinal epithelium. Id2-deficient embryonic epithelial cells cultured ex vivo strongly activate Wnt target genes as well as markers of neoplastic transformation and form fast growing undifferentiated spheroids. Furthermore, adult ISCs from Id2-deficient mice display a distinct transcriptional signature, supporting an essential role for Id2 in the correct specification of ISCs. © 2017 The Authors.

  16. System Virtualization and Efficient ID Transmission Method for RFID Tag Infrastructure Network

    Directory of Open Access Journals (Sweden)

    Shin-ichi Kuribayashi

    2010-11-01

    Full Text Available The use of RFID tag which identifies a thing and an object will be expanded with progress of ubiquitoussociety, and it is necessary to study how to construct RFID network system as a social infrastructure likethe Internet. First, this paper proposes the virtualization method of RFID tag network system to enablethe same physical RFID network system to be used by multiple different service systems. The systemvirtualization not only reduces the system cost but also can dramatically reduce the installation space ofphysical readers and the operation cost. It is proposed that all equipments in the RFID network systemexcept RFID tag could be shared with the conventional virtual technologies. Then, this paper proposesthe conditional tag ID processing and the efficient tag ID transmission method which can greatly reducethe processing time and processing load in RFID tag Infrastructure network The conditional tag IDprocessing allows that tag ID is valid only at a certain time zone of day or in a certain area. The efficienttag ID transmission method uses the virtual network address of the service center as a part of the ID of anRF tag, which allows the direct ID forwarding to the service center.

  17. 基于生物特征的Auto ID技术——BioID%Automated Biometric Personal Identification and Verification--BioID

    Institute of Scientific and Technical Information of China (English)

    李雄军; 苏廷弼

    2002-01-01

    文章全面而系统地综述了基于生物特征的Auto ID-BioID.重点分析了该技术与系统中的特殊问题,包括BioID系统通用模型、所使用的生物特征的类型、识别技术与系统设计上的共性与差异、性能要求及信号传输和存储两个关键问题;比较了声音、掌形、签名、脸谱、指纹、视网膜和虹膜几种典型的BioID技术的特点、性能与应用现状;探讨了BioID技术发展的动向与前景.

  18. The mathematical model for ID-201 semiconductor single photon counter%ID-201单光子计数器计数模型研究

    Institute of Scientific and Technical Information of China (English)

    曹攀; 朱广浩; 金飚兵

    2016-01-01

    InGaAs半导体单光子探测器具备探测性能强,集成度高等优势,在光谱分析和量子通信等领域有广泛的应用.本文以ID Quantique公司出品的ID-201半导体单光子计数器为研究对象,结合计数器核心部件雪崩光电二极管的工作原理探究其计数光子时的内部过程,推导出每秒钟光子计数值和该计数器几个重要参数触发频率(trigger frequency),门脉冲宽度(gate width),门强制关闭时间(dead time),探测效率(detection efficiency)之间的数学表达式.推导过程着重分析了计数门脉冲的关闭效应对光子探测概率的影响.首先利用泊松分布求解光子计数值与探测效率(detection efficiency)之间的关系,然后将计数过程分成两大部分,分析计数结果与门强制关闭时间(dead time)之间关系.求解得表达式后,利用1550 nm激光器作为ID-201的输入光源,在各种不同实验条件下,对该表达式的正确性进行了检验.%The technology of photon counting has wide applications in physics and electrical engineering.Single photon detectors based on avalanche photodiodes are attractive,Considering their advantages including compact sizes,broad spectrum of responses,and high detection efficiencies.The semiconductor single photon detector normally works in the gated mode,where photons can only be detected when the gate is open.However,if any photon is detected by the photon counter during the gate,several gates after the detection will be forced to shut down so that no photon can be detected during this period.The timing duration that the gates are down is called the dead time.This article mainly focuses on the photon counting performance of the ID-201 semiconductor photon counter,which is produced by the ID Quantique company.The purpose is to derive a photon counting formula for ID-201 and verify it using experiments.Starting with a simple Poisson distribution,we first studied the relationship between the detection

  19. Risk Factors Assessment of the Difficult Intubation using Intubation Difficulty Scale (IDS).

    Science.gov (United States)

    K Nasa, Vaibhav; S Kamath, Shaila

    2014-07-01

    The major responsibility of anaesthesiologist is to maintain adequate gas exchange in his patients in all circumstances and this require that patency of upper airway is constantly maintained. Problems with upper airway management are among the most frequent causes of anaesthetic mishaps. Using intubation difficulty scale (IDS) we made an attempt to objectively assess the predictors of difficult intubation. We assessed classical bedside tests such as modified Mallampati test, Thyromental distance test and also neck extension test. We prospectively observed 400 patients undergoing general anaesthesia with endotracheal intubation, for each patient intubation difficulty score was recorded during intubation. Risk factors assessment of difficult intubation done using IDS. Risk factor assessed includes modified mallampati class III and IV, thyromental distance ≤ 6cm and neck extension intubation (IDS, 0 to 2), slightly difficult intubation (IDS, 3 to 4) and difficult intubation (IDS 5). Preoperative airway assessment was done by thyromental distance measurement, neck extension measurement and modified mallampati test. Data was analysed using Receiver operating characteristic curve (ROC) and area under curve (AUC) for each test computed. pintubation was 8% and there were no failure to intubate the trachea. The AUC were as follows: modified Mallampati test 0.473 (ppredictor of difficult intubation (IDS≥5) in comparison to Thyromental test and modified mallampati test.

  20. Dynamic Programming for Single Nucleotide Polymorphism ID Identification in Systematic Association Studies

    Directory of Open Access Journals (Sweden)

    Cheng-Hong Yang

    2009-04-01

    Full Text Available Single nucleotide polymorphisms (SNPs play an important role in personalized medicine. However, the SNP data reported in many association studies provide only the SNP nucleotide/amino acid position, without providing the SNP ID recorded in National Center for Biotechnology Information databases. A tool with the ability to provide SNP ID identification, with a user-friendly interface, is needed. In this paper, a dynamic programming algorithm was used to compare homologs when the processed input sequence is aligned with the SNP FASTA database. Our novel system provides a web-based tool that uses the National Center for Biotechnology Information dbSNP database, which provides SNP sequence identification and SNP FASTA formats. Freely selectable sequence formats for alignment can be used, including general sequence formats (ACGT, [dNTP1/dNTP2] or IUPAC formats and orientation with bidirectional sequence matching. In contrast to the National Center for Biotechnology Information SNP-BLAST, the proposed system always provides the correct targeted SNP ID (SNP hit, as well as nearby SNPs (flanking hits, arranged in their chromosomal order and contig positions. The system also solves problems inherent in SNP-BLAST, which cannot always provide the correct SNP ID for a given input sequence. Therefore, this system constitutes a novel application which uses dynamic programming to identify SNP IDs from the literature and keyed-in sequences for systematic association studies. It is freely available at http://bio.kuas.edu.tw/SNPosition/.

  1. Changes of osteosarcoma cell biological behavior afterId1 gene silencing by siRNA

    Institute of Scientific and Technical Information of China (English)

    De-Li Xu

    2016-01-01

    Objective:To study the changes of osteosarcoma cell biological behaviors proliferation, migration and invasion afterId1gene silencing by siRNA.Methods:Osteosarcoma HEK293 cell lines were cultured and transfected with Id1-siRNA and NC-siRNA respectively, cell proliferation, migration and invasion were detected after 24 h and 48 h of transfection, and the expression levels of proliferation-promoting genes, proliferation-inhibiting genes as well as migration and invasion-related genes in cells were detected after 48 h of transfection. Results:After 24 h and 48 h of transfection, cell OD value and the number of invasive cells of Id1-siRNA group were significantly lower than those of NC-siRNA group, and scratch area was significantly larger than that of NC-siRNA group; after 48 h of transfection, hnRNP A2, hnRNP B1, S100A6, RUNX2, Aurora-A, Grb2, Gab2 and Rap2a expression levels of Id1-siRNA group were significantly lower than those of NC-siRNA group, and p53, TAp73 and IGFBP5 were significantly higher than those of NC-siRNA group.Conclusions:Id1 gene silencing by siRNA can inhibit osteosarcoma cell proliferation, migration and invasion.

  2. Relationship between major depressive disorder and ACE gene I/D polymorphism in a Turkish population

    Directory of Open Access Journals (Sweden)

    Sema Inanir

    2016-04-01

    Full Text Available Abstract Background Major depressive disorder (MDD is a complex disease and a significant health problem that is prevalent across the world. Angiotensin-converting enzyme (ACE has an important role in renin-angiotensin system (RAS and converts inactive angiotensin I to a potent vasopressor and aldosterone-stimulating peptide angiotensin II. Levels of ACE in plasma vary according to the insertion/deletion (I/D polymorphism of ACE gene. Objective The aim of the current study was to examine the influence ACE gene I/D variations on the risk of MDD. Methods In the present case-control study, we analyzed ACE I/D polymorphism in 346 MDD patients and 210 healthy subjects using polymerase chain reaction technique. Results Comparing the two groups, no significant difference was observed with regard to either genotype distributions or allele frequencies of the I/D polymorphism of ACE gene. Discussion Our findings suggest that the ACE I/D polymorphism is not associated with MDD in Turkish case-control study. Further studies are still needed.

  3. ACE I/D gene polymorphism in diabetic nephropathy: Clinical implications

    Directory of Open Access Journals (Sweden)

    M. Kaleemullah Khan

    2011-01-01

    Full Text Available Diabetic nephropathy (DN is a major microvascular complication accounting for about 30% of End-Stage Renal Disease (ESRD cases. An insertion/deletion (I/D polymorphism of the gene encoding angiotensin-I converting enzyme (ACE is reported to be a candidate gene predisposing to diabetic nephropathy. Accordingly, we investigated the ACE I/D gene polymorphism in 52 Type 2 diabetes mellitus (T2DM cases suffering from nephropathy as assessed by 24 hrs urinary protein levels. 50 age and sex matched healthy subjects served as controls. ACE I/D genotyping was carried out by polymerase chain reaction (PCR amplification using allele specific primers. The frequencies of ACE DD, ID and II genotypes in the diabetic nephropathy patients were 38.5% , 50% and 11.5% and in the control subjects, 22%, 38% and 40% respectively. There was an increase of 16.5% in the frequency of DD genotype in the patients compared to controls. The frequency of D allele in the patients was 63% which was found to be statistically significant (p< 0.05, Odds ratio=2.6 compared to 41% in the controls. These results indicate that Type 2 diabetic patients with D allele (those with DD & ID genotypes have more than two fold risk of developing nephropathy. Clinical implications of ACE genotyping in planning for patient’s management have been discussed.

  4. Increasing the Efficiency of IDS Systems by Hardware Implementation of Packet Capturing

    Directory of Open Access Journals (Sweden)

    Zeinab Latifi

    2013-08-01

    Full Text Available Capturing is the first step in intrusion detection system (IDS. Having wire speed, omitting the OS from capturing process and no need for making a copy of packets from the system’s environment to the user’s environment are some of the system characteristics. If these requirements are not met, packet capture system is considered as the main bottleneck of IDS and the overall efficiency of this system will be influenced. Presence of all these three characteristics calls for utilization of hardware methods. In this paper, by using of FPGA, a line sniffing and load balancing system are designed in order to be applied in IDS systems. The main contribution of our work is the feasibility of attaching labels to the beginning part of each packet, aiming at quick easy access of other IDS modules to information of each packet and also reducing workload of these modules. Packet classification in the proposed system can be configured to 2, 3, and 5 tuple, which can also be applied in IDS detection module in addition to load balancing part of this system. Load balancing module uses Hash table and its Hash function has the least flows collisions. This system is implemented on a set of virtex 6 and 7 families and is able to capture packets 100% and perform the above mentioned processes by speed of 12 Gbit/s.

  5. FHL2 Antagonizes Id1-Promoted Proliferation and Invasive Capacity of Human MCF-7 Breast Cancer Cells

    Institute of Scientific and Technical Information of China (English)

    Wei-dong Han; Zhi-qiang Wu; Ya-li Zhao; Yi-ling Si; Ming-zhou Guo; Xiao-bing Fu

    2010-01-01

    Objective:FHL2 was previously identified to be a novel interacting factor of Id family proteins.The aim of this study was to investigate,the effects of FHL2 on Id1-mediated transcriptional regulation activity and its oncogenic activity in human breast cancer cells.Methods:Cell transfection was performed by Superfect reagent.Id1 stably overexpressed MCF-7 cells was cloned by G418 screening.The protein level of Id1 was detected by western blot analysis.Dual relative luciferase assays were used to measure the effect of E47-mediated transcriptional activity in MCF-7 human breast cancer cells.MTT assay was used to measure cell proliferation.Transwell assay was used to measure the invasive capacity of MCF-7 cancer cells.Results:The basic helix-loop-helix(bHLH)factor E47-mediated transcription activity was markedly repressed by Id1 in MCF-7 cells.This Id1-mediated repression was effectively antagonized by FHL2 transduction.Overexpression of Id1 markedly promoted the proliferation rate and invasive capacity of MCF-7 cells; however,these effects induced by Id1 were significantly suppressed by overexpression of FHL2 in cells.Conclusion:FHL2 can inhibit the proliferation and invasiveness of human breast cancer cells by repressing the functional activity of Id1.These findings provide the basis for further investigating the functional roles of FHL2-Id1 signaling in the carcinogenesis and development of human breast cancer.

  6. Analysis of data mining classification by comparison of C4.5 and ID algorithms

    Science.gov (United States)

    Sudrajat, R.; Irianingsih, I.; Krisnawan, D.

    2017-01-01

    The rapid development of information technology, triggered by the intensive use of information technology. For example, data mining widely used in investment. Many techniques that can be used assisting in investment, the method that used for classification is decision tree. Decision tree has a variety of algorithms, such as C4.5 and ID3. Both algorithms can generate different models for similar data sets and different accuracy. C4.5 and ID3 algorithms with discrete data provide accuracy are 87.16% and 99.83% and C4.5 algorithm with numerical data is 89.69%. C4.5 and ID3 algorithms with discrete data provides 520 and 598 customers and C4.5 algorithm with numerical data is 546 customers. From the analysis of the both algorithm it can classified quite well because error rate less than 15%.

  7. ID-based deniable ring authentication with constant-size signature

    Institute of Scientific and Technical Information of China (English)

    Lingling WANG; Guoyin ZHANG; Chunguang MA

    2008-01-01

    Deniable ring authentication allows a member of an ad-hoc sunset of participants to authenticate a message without revealing which member has issued the signature, and the verifier cannot transfer the signature to any third party. It is an important cryptographic primitive for privacy and anonymous communication. Unfortunately, the size of the signature of the proposed deniable ring authentication is dependent on the size of the ring. It is inefficient especially when the size of the ring is large. In this paper, we propose an ID-based version of deniable ring authentication. We present a generic construction which uses dynamic accumu-lators to construct ID-based deniable ring authentication with constant-size signature. We also give an ID-based deni-able ring authentication based on bilinear pairings, which is proved to be secure in the random oracle model.

  8. Formalization and Parsing of Typed Unification-Based ID/LP Grammars

    CERN Document Server

    Morawietz, F

    1999-01-01

    This paper defines unification based ID/LP grammars based on typed feature structures as nonterminals and proposes a variant of Earley's algorithm to decide whether a given input sentence is a member of the language generated by a particular typed unification ID/LP grammar. A solution to the problem of the nonlocal flow of information in unification ID/LP grammars as discussed in Seiffert (1991) is incorporated into the algorithm. At the same time, it tries to connect this technical work with linguistics by presenting an example of the problem resulting from HPSG approaches to linguistics (Hinrichs and Nakasawa 1994, Richter and Sailer 1995) and with computational linguistics by drawing connections from this approach to systems implementing HPSG, especially the TROLL system, Gerdemann et al. (forthcoming).

  9. Comportamiento del inversionista a diferentes niveles de inversión en I+D

    Directory of Open Access Journals (Sweden)

    Ángel Samaniego Alcántar

    2012-01-01

    Full Text Available Este trabajo analiza, usando una metodología alterna a la existente en la literatura del tema, la existencia de rendimientos anormales en el corto plazo ocasionados por cambios en la intensidad de la inversión en proyectos de investigación y desarrollo, I+D (R&D intensity. Se observa que los inversionistas obtienen rendimientos anormales en portafolios de empresas que incrementan entre cinco a diez unidades la intensidad del I+D (o cuando este incremento es mayor a 25 unidades. Sin embargo, ante decrementos en la intensidad del I+D no se observan desviaciones en los rendimientos esperados; asimismo, el rendimiento anormal es mayor en empresas de alta tecnología. El periodo analizado es 2001-2006 en los mercados AMEX, NYSE y NASDAQ.

  10. HUD Program Income Limits

    Data.gov (United States)

    Department of Housing and Urban Development — Income limits used to determine the income eligibility of applicants for assistance under three programs authorized by the National Housing Act. These programs are...

  11. HUD Insured Hospitals

    Data.gov (United States)

    Department of Housing and Urban Development — The Office of Healthcare Programs (OHP), previously known as the Office of Insured Health Care Facilities, is located within the Office of Housing and administers...

  12. ACE I/D genotype, adiposity, and blood pressure in children

    Directory of Open Access Journals (Sweden)

    Rothschild Max

    2009-03-01

    Full Text Available Abstract Background Angiotensin converting enzyme (ACE is a possible candidate gene that may influence both body fatness and blood pressure. Although several genetic studies have been conducted in adults, relatively few studies have examined the contribution of potential candidate genes, and specifically ACE I/D, on adiposity and BP phenotypes in childhood. Such studies may prove insightful for the development of the obesity-hypertension phenotype early in life. The purpose of this study was to examine differences in body fatness and resting blood pressure (BP by ACE I/D genotype, and determine if the association between adiposity and BP varies by ACE I/D genotype in children. Methods 152 children (75 girls, 77 boys were assessed for body composition (% body fat using dual energy x-ray absorbtiometry and resting BP according to American Heart Association recommendations. Buccal cell samples were genotyped using newly developed PCR-RFLP tests for two SNPs (rs4341 and rs4343 in complete linkage disequilibrium with the ACE I/D polymorphism. Partial correlations were computed to assess the ociations between % body fat and BP in the total sample and by genotype. ANCOVA was used to examine differences in resting BP by ACE I/D genotype and fatness groups. Results Approximately 39% of youth were overfat based on % body fat (>30% fat in girls, 25% fat in boys. Body mass, body mass index, and fat-free mass were significantly higher in the ACE D-carriers compared to the II group (p Conclusion ACE D-carriers are heavier than ACE II children; however, BP did not differ by ACE I/D genotype but was adversely influenced in the overfat D-carriers. Further studies are warranted to investigate the genetics of fatness and BP phenotypes in children.

  13. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells

    Science.gov (United States)

    Mody, Avani A.; Wordinger, Robert J.; Clark, Abbot F.

    2017-01-01

    Purpose Increased expression of TGF-β2 in primary open-angle glaucoma (POAG) aqueous humor (AH) and trabecular meshwork (TM) causes deposition of extracellular matrix (ECM) in the TM and elevated IOP. Bone morphogenetic proteins (BMPs) regulate TGF-β2–induced ECM production. The underlying mechanism for BMP4 inhibition of TGF-β2–induced fibrosis remains undetermined. Bone morphogenic protein 4 induces inhibitor of DNA binding proteins (ID1, ID3), which suppress transcription factor activities to regulate gene expression. Our study will determine whether ID1and ID3 proteins are downstream targets of BMP4, which attenuates TGF-β2 induction of ECM proteins in TM cells. Methods Primary human TM cells were treated with BMP4, and ID1 and ID3 mRNA, and protein expression was determined by quantitative PCR (Q-PCR) and Western immunoblotting. Intracellular ID1 and ID3 protein localization was studied by immunocytochemistry. Transformed human TM cells (GTM3 cells) were transfected with ID1 or ID3 expression vectors to determine their potential inhibitory effects on TGF-β2–induced fibronectin and plasminogen activator inhibitor-I (PAI-1) protein expression. Results Basal expression of ID1-3 was detected in primary human TM cells. Bone morphogenic protein 4 significantly induced early expression of ID1 and ID3 mRNA (P < 0.05) and protein in primary TM cells, and a BMP receptor inhibitor blocked this induction. Overexpression of ID1 and ID3 significantly inhibited TGF-β2–induced expression of fibronectin and PAI-1 in TM cells (P < 0.01). Conclusions Bone morphogenic protein 4 induced ID1 and ID3 expression suppresses TGF-β2 profibrotic activity in human TM cells. In the future, targeting specific regulators may control the TGF-β2 profibrotic effects on the TM, leading to disease modifying IOP lowering therapies. PMID:28159972

  14. Suurnimed jäid müümata / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    9. mai Christie' oksjonist, müümata jäänud Picasso, Degas', Cezanne'i tööd. 8. mai Sotheby oksjonist, kus edukalt müüdi töid S. J. Seegeri kogust, 3,85 miljoni dollari eest M. Beckmanni "Perseuse viimane katsumus". Sotheby kaasaegse kunsti oksjonil New Yorgis müüdi 5,6 miljoni dollari eest J. Koonsi skulptuur M. Jacksonist. Müümata jäid A. Warholi "Viis supipurki", A. Calderi 3 skulptuuri

  15. Pairing-Free ID-Based Key-Insulated Signature Scheme

    Institute of Scientific and Technical Information of China (English)

    Guo-Bin Zhu; Hu Xiong; Zhi-Guang Qin

    2015-01-01

    Abstract⎯Without the assumption that the private keys are kept secure perfectly, cryptographic primitives cannot be deployed in the insecure environments where the key leakage is inevitable. In order to reduce the damage caused by the key exposure in the identity-based (ID-based) signature scenarios efficiently, we propose an ID-based key-insulated signature scheme in this paper, which eliminates the expensive bilinear pairing operations. Compared with the previous work, our scheme minimizes the computation cost without any extra cost. Under the discrete logarithm (DL) assumption, a security proof of our scheme in the random oracle model has also been given.

  16. Tamaño, restricciones financieras e inversión en i+d

    OpenAIRE

    María Ángeles Marra Domínguez

    2007-01-01

    Este trabajo analiza empíricamente los efectos de restricciones de liquidez en la inversión en actividades de I+D de una muestra de empresas manufactureras españolas clasificada según su tamaño durante el periodo 1991-1999. Las estimaciones confirman que la inversión en I+D emprendida por las empresas de menor tamaño presenta una mayor sensibilidad al cash flow y una relación negativa fuerte con la tasa de endeudamiento, lo que sugiere la posible presencia de restricciones financieras. Por el...

  17. MA- IDS: A Distributed Intrusion Detection System Based on Data Mining

    Institute of Scientific and Technical Information of China (English)

    SUN Jian-hua; JIN Hai; CHEN Hao; HAN Zong-fen

    2005-01-01

    Aiming at the shortcomings in intrusion detection systems (IDSs) used in commercial and research fields,we propose the MA-IDS system, a distributed intrusion detection system based on data mining. In this model, misuse intrusion detection system (MIDS) and anomaly intrusion detection system (AIDS) are combined. Data mining is applied to raise detection performance, and distributed mechanism is employed to increase the scalability and efficiency. Host- and network-based mining algorithms employ an improved Bayesian decision theorem that suits for real security environment to minimize the risks incurred by false decisions. We describe the overall architecture of the MA-IDS system, and discuss specific design and implementation issue.

  18. Evaluation of S. aureus ID, a New Chromogenic Agar Medium for Detection of Staphylococcus aureus

    OpenAIRE

    Perry, John D.; Rennison, Claire; Butterworth, Lynne A.; Hopley, Andrew L. J.; Gould, F. Kate

    2003-01-01

    S. aureus ID (bioMérieux, La Balme Les Grottes, France) is a new chromogenic agar medium designed to enable the isolation of staphylococci and the specific identification of Staphylococcus aureus. S. aureus produces green colonies on this medium due to production of α-glucosidase. To evaluate this medium, a total of 350 wound swabs were cultured onto S. aureus ID, CHROMagar Staph. aureus, and conventional media routinely used in our laboratory. After 18 to 20 h of incubation, 96.8% of strains...

  19. Projectc conception for city logistics with utilization of IDS element applicated to the Nitra city

    Directory of Open Access Journals (Sweden)

    Michal Balog

    2010-02-01

    Full Text Available Nowadays traffic situation in the town-residential area is characterized by growing requirement for quality and quantityof transfer performance and services that result in congestion increasing in the some towns. Currently the similar problem has Nitracity, where it is necessary to solve this situation immediately. One of the possibilities of increasing traffic fluency is to extend roads, butin case of Nitra that possibility is irrelevant because of non-available space. Other possibility is an utilization of IDS elements(Intelligent Transport System. The contribution presents the conception of transportation in the town, founded on creation of trafficcircles with subsequent IDS elements application.

  20. Comportamiento del inversionista a diferentes niveles de inversión en I+D

    OpenAIRE

    Ángel Samaniego Alcántar; Carlos Omar Trejo Pech; Samuel Mongrut Montalván; Darcy Fuenzalida O´Shee

    2012-01-01

    Este trabajo analiza, usando una metodología alterna a la existente en la literatura del tema, la existencia de rendimientos anormales en el corto plazo ocasionados por cambios en la intensidad de la inversión en proyectos de investigación y desarrollo, I+D (R D intensity). Se observa que los inversionistas obtienen rendimientos anormales en portafolios de empresas que incrementan entre cinco a diez unidades la intensidad del I+D (o cuando este incremento es mayor a 25 unidades). Sin embargo,...

  1. Investigation on AQ11, ID3 and the Principle of Discernibility Matrix

    Institute of Scientific and Technical Information of China (English)

    王珏; 崔佳; 赵凯

    2001-01-01

    The principle of discernibility matrix serves as a tool to discuss and analyze two algorithms of traditional inductive machine learning, AQ11 and ID3. The results are: (1) AQ11 and its family can be completely specified by the principle of discernibility matrix; (2) ID3 can be partly, but not naturally, specified by the principle of discernibility matrix; and (3) The principle of discernibility matrix is employed to analyze Cendrowska sample set, and it shows the weaknesses of knowledge representation style of decision tree in theory.

  2. Gestión de la incertidumbre en los proyectos de I+D

    OpenAIRE

    García Muntión, Paula

    2014-01-01

    En el presente TFM se estudian diferentes metodologías y herramientas con el objeto de presentar una propuesta metodológica basada en el PMBOK que facilite la gestión de los Proyectos I+D. Para realizar esta propuesta y facilitar la implantación de una gestión de proyectos adecuada a las características de los proyectos de I+D será fundamental identificar cuáles son los principales bloqueadores y facilitadores que se encuentran. La propuesta metodológica deberá contemplar el tratamiento de...

  3. Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse

    Directory of Open Access Journals (Sweden)

    Yokota Yoshifumi

    2004-12-01

    Full Text Available Abstract Background During pregnancy, the mammary glands from Id2 mutant animals are deficient in lobulo-alveolar development. This failure of development is believed to be due to a proliferation defect. Methods We have asked whether functional Id2 expression is necessary for Wnt induced mammary hyperplasia, side branching, and cancer, by generating mice expressing a Wnt1 transgene in an Id2 mutant background. Results We show in this work that forced expression of Wnt1 in the mammary gland is capable of overcoming the block to proliferation caused by the absence of Id2. We also show that Wnt1 expression is able to cause mammary tumors in an Id2 mutant background. Conclusions We conclude that functional Id2 expression is not required for Wnt1 to induce mammary hyperplasia and mammary tumors.

  4. Combination of electron beam irradiation and thermal treatment to enhance the shelf-life of traditional Indian fermented food (Idli)

    Science.gov (United States)

    Mulmule, Manoj D.; Shimmy, Shankar M.; Bambole, Vaishali; Jamdar, Sahayog N.; Rawat, K. P.; Sarma, K. S. S.

    2017-02-01

    Idli, a steam-cooked breakfast food item consumed in India, is famous as a staple food for its spongy texture and unique fermented taste. Idli preparation is a time consuming process; although instant Idli pre-mixes as powder or batter are available in the market, they do not have the distinctive taste and aroma similar to the Idli prepared at home. Hence ready-to-eat (RTE) form of this food is in demand. Therefore, an attempt was made to prepare RTE Idli bearing similar taste as home-cooked Idli with an extended shelf-life of up to two months at an ambient temperature using Electron Beam Irradiation (EBI) at dosages 2.5 kGy, 5 kGy and 7.5 kGy and combination processing comprised of EBI dosage at 2.5 kGy and thermal treatment (80 °C for 20 min). The treated Idli's were microbiologically and sensorially evaluated at storage periods of zero day, 14 days, 30 days and 60 days. Idli's irradiated at 7.5 kGy and subjected to combination processing at 2.5 kGy and thermal treatment were shelf-stable for 60 days. 2.5 kGy and 5 kGy radiation dosages alone were not sufficient to preserve Idli samples for more than 14 days. Undesirable change in sensory properties of Idli was observed at an EBI dosage of 7.5 kGy. Sensory properties of combination processed Idli's were found to undergo minor change over the storage period. The present work suggests that lowest radiation dosage in combination with thermal treatment could be useful to achieve the extended shelf-life without considerably impairing the organoleptic quality of Ready-to-Eat Idli.

  5. Attitudes of Israeli Teachers and Paraprofessionals towards the New Definition of ID and Their Willingness to Cope with Special Education Law Changes

    Science.gov (United States)

    Lifshitz, Hefziba; Nissim, Shoshanna; Cohen, Sara

    2008-01-01

    Attitudes of teachers (N = 96) and paraprofessionals (N = 48) working with students with intellectual disability (ID) towards the new definition of ID (Luckasson et al., 1992, 2002), was examined. The main innovation of the new definition of ID is the cancellation of the four ID levels, suggesting an optimistic view, especially towards individuals…

  6. 77 FR 59639 - Bear Lake National Wildlife Refuge, Bear Lake County, ID and Oxford Slough Waterfowl Production...

    Science.gov (United States)

    2012-09-28

    ... public, including opportunities for hunting, fishing, wildlife observation and photography, and... review at the following libraries: Bear Lake County Library, 138 North 6th Street, Montpelier, ID 83254...

  7. What's Going on in Your Professor's Head? Demonstrating the Id, Ego, and Superego

    Science.gov (United States)

    Segrist, Dan J.

    2009-01-01

    This article describes an in-class activity designed to demonstrate Freud's structural theory of the psyche, specifically the roles of the id, ego, and superego, as well as the interplay among them. Additionally, the activity visually illustrates Freud's ideas about the levels of consciousness associated with these 3 components. Pre-post quiz…

  8. Permutations with Kazhdan-Lusztig polynomial P_{id,w}(q) = 1 + q^h

    OpenAIRE

    Woo, Alexander; Billey, Sara; Weed, Jonathan

    2008-01-01

    Using resolutions of singularities introduced by Cortez and a method for calculating Kazhdan-Lusztig polynomials due to Polo, we prove the conjecture of Billey and Braden characterizing permutations w with Kazhdan-Lusztig polynomial P_{id,w}(q)=1+q^h for some h.

  9. 76 FR 36896 - Salmon-Challis National Forest, ID; Forestwide Invasive Plant Treatment Environmental Impact...

    Science.gov (United States)

    2011-06-23

    ... Forest Service Salmon-Challis National Forest, ID; Forestwide Invasive Plant Treatment Environmental... impact statement. SUMMARY: Invasive plants have been identified as a major threat to the biological diversity and ecological integrity within and outside the Salmon-Challis National Forest. Invasive plants...

  10. Accelerated fermentation of Idli batter using Eleusine coracana and Pennisetum glaucum.

    Science.gov (United States)

    Chelliah, Ramachandran; Ramakrishnan, Sudha Rani; Premkumar, Divya; Antony, Usha

    2017-08-01

    The present study focuses on reduction in fermentation time of idli batter and its enrichment with calcium and iron using finger millet and pearl millet. Fermentation time decreased from 12 to 6 h with addition of finger millet and to 8 h with pearl millet. Rate of fermentation, bulk density, viscosity, microbial changes and particle morphology were assessed in the batter; nutritional quality, sensory, phytochemicals and internal characteristics of idli were investigated. The color and texture characteristics of both batter and idli were evaluated. The pH and titratable acidity of control batter at 6 h was 5.32 and 0.27%, addition of finger and pearl millet changed to 4.32, 0.45% and 4.53, 0.45% at respective fermentation times (6 and 8 h). The viable yeast, lactic acid bacteria and total bacterial count (log CFU g(-1)) in the batters increased with time, reaching 1.26, 3.85, 4.56 (control); 2.32, 9.84, 9.58 (finger millet) and 1.76, 7.34, 7.74 (pearl millet) respectively at the end of 6 h of fermentation. Addition of finger millet and pearl millet flour (10% w/w) to the batter enhanced the dietary fiber by 28 and 23%, calcium by 113 and 56%, iron by 51 and 258% in the respective idlies when compared with the control.

  11. 76 FR 46721 - Salmon-Challis National Forest, ID; Upper North Fork HFRA Ecosystem Restoration Project...

    Science.gov (United States)

    2011-08-03

    ... this project area to improve the health of the ecosystem and reach the desired future condition. DATES...; ] DEPARTMENT OF AGRICULTURE Forest Service Salmon-Challis National Forest, ID; Upper North Fork HFRA Ecosystem... the potential for large-scale, high-intensity wildfires that threaten human life, property, and...

  12. RPD: Reusable Pseudo-Id Distribution for a Secure and Privacy Preserving VANET

    Directory of Open Access Journals (Sweden)

    Sulaiman Ashraph

    2013-08-01

    Full Text Available In any VANET, security and privacy are the two fundamental issues. Obtaining efficient security in vehicular communication is essential without compromising privacy-preserving mechanisms. Designing a suitable protocol for VANET by having these two issues in mind is challenging because efficiency, unlinkablity and traceability are the three qualities having contradictions between them. In this paper, we introduce an efficient Reusable Pseudo-id Distribution (RPD scheme. The Trusted Authority (TA designating the Road Side Units (RSUs to generate n reusable pseudo ids and distribute them to the On Board Units (OBUs on request characterizes the proposed protocol. RSUs issue the aggregated hashes of all its valid pseudo-ids along with a symmetric shared key and a particular pseudo-id to each vehicle that enters into its coverage range. Through this the certificates attached to the messages can be eliminated and thus resulting in a significantly reduced packet size. The same anonymous keys can then be re-distributed by the RSUs episodically to other vehicles. We analyze the proposed protocol extensively to demonstrate its merits and efficiency.

  13. Enrolment Data of Disabled Students Of IGNOU: A Case Study Using ID3

    Directory of Open Access Journals (Sweden)

    Nidhi Chopra

    2013-06-01

    Full Text Available In this paper, a methodology based on ID3 – a decision based learning technique for classification of disabled students of IGNOU has been evolved, for creating peer-to-peer groups. This can facilitate an environment for mutual help and academic interaction. The purpose is to promote blended social learning.

  14. Support and Self-Efficacy among Latino and White Parents of Children with ID

    Science.gov (United States)

    Cohen, Shana R.; Holloway, Susan D.; Dominguez-Pareto, Irenka; Kuppermann, Miriam

    2015-01-01

    Research indicates that mothers of children with ID who receive familial support experience less stress than those who receive less support. Less is known about the relation of support to mothers' evaluation of parenting self-efficacy, particularly in Latino families. We examined the relationship of different types of family support to life…

  15. 61 FR 42052 - Owyhee Resource Area, ID; Resource Management Plan, etc.

    Science.gov (United States)

    1996-08-13

    ... Bureau of Land Management Owyhee Resource Area, ID; Resource Management Plan, etc. AGENCY: Bureau of Land... Management Plan (RMP) and associated draft Environmental Impact Statement (EIS) for the Owyhee Resource Area... be sent to: Owyhee Area Manager, Bureau of Land Management, Boise Field Office, 3948...

  16. 70 FR 9098 - Notice of Realty Action, Sale of Public Land in Owyhee County, ID

    Science.gov (United States)

    2005-02-24

    ... Bureau of Land Management Notice of Realty Action, Sale of Public Land in Owyhee County, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Realty Action, Sale of Public Land in Owyhee... located in Owyhee County, Idaho is suitable for direct sale to Owyhee County under Sections 203 and 209...

  17. 81 FR 23746 - Temporary Road Closure on Public Lands in Owyhee County, ID

    Science.gov (United States)

    2016-04-22

    ... Bureau of Land Management Temporary Road Closure on Public Lands in Owyhee County, ID AGENCY: Bureau of... 1-mile road segment that crosses public lands located in Owyhee County, Idaho, approximately 5 miles... the Owyhee Field Office, 20 First Avenue West, Marsing, Idaho, 83639. National Environmental...

  18. 61 FR 11862 - Shooting Closures and Restrictions in Ada, Canyon, Elmore, and Owyhee Counties, ID

    Science.gov (United States)

    1996-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Shooting Closures and Restrictions in Ada, Canyon, Elmore, and Owyhee Counties, ID AGENCY: Bureau of Land... Bruneau, Kuna, and Owyhee Management Framework Plans. Violation of this order is punishable by a fine...

  19. 77 FR 75654 - Notice of Temporary Closures on Public Lands in Owyhee County, ID

    Science.gov (United States)

    2012-12-21

    ... Bureau of Land Management Notice of Temporary Closures on Public Lands in Owyhee County, ID AGENCY... are in effect on public lands administered by the Owyhee Field Office, Bureau of Land Management (BLM... contact Loretta Chandler, Owyhee Field Office Manager at 20 First Ave. West, Marsing, Idaho, 83639,...

  20. Identification of an active ID-like group of SINEs in the mouse.

    Science.gov (United States)

    Kass, David H; Jamison, Nicole

    2007-09-01

    The mouse genome consists of five known families of SINEs: B1, B2, B4/RSINE, ID, and MIR. Using RT-PCR we identified a germ-line transcript that demonstrates 92.7% sequence identity to ID (excluding primer sequence), yet a BLAST search identified numerous matches of 100% sequence identity. We analyzed four of these elements for their presence in orthologous genes in strains and subspecies of Mus musculus as well as other species of Mus using a PCR-based assay. All four analyzed elements were identified either only in M. musculus or exclusively in both M. musculus and M. domesticus, indicative of recent integrations. In conjunction with the identification of transcripts, we present an active ID-like group of elements that is not derived from the proposed BC1 master gene of ID elements. A BLAST of the rat genome indicated that these elements were not in the rat. Therefore, this family of SINEs has recently evolved, and since it has thus far been observed mainly in M. musculus, we refer to this family as MMIDL.

  1. BICM-ID with Physical Layer Network Coding in TWR Free Space Optical Communication Links

    Directory of Open Access Journals (Sweden)

    Alaa A. Saeed Al-Rubaie

    2017-07-01

    Full Text Available Physical layer network coding (PNC is a promising technique to improve the network throughput in a two-way relay (TWR channel for two users to exchange messages across a wireless network. The PNC technique incorporating a TWR channel is embraced by a free space optical (FSO communication link for full utilization of network resources, namely TWR-FSO PNC. In this paper, bit interleaved coded modulation with iterative decoding (BICM-ID is adopted to combat the deleterious effect of the turbulence channel by saving the message being transmitted to increase the reliability of the system. Moreover, based on this technique, comparative studies between end-to-end BICM-ID code, non-iterative convolutional coded and uncoded systems are carried out. Furthermore, this paper presents the extrinsic information transfer (ExIT charts to evaluate the performance of BICM-ID code combined with the TWR-FSO PNC system. The simulation results show that the proposed scheme can achieve a significant bit error rate (BER performance improvement through the introduction of an iterative process between a soft demapper and decoder. Similarly, Monte Carlo simulation results are provided to support the findings. Subsequently, the ExIT functions of the two receiver components are thoroughly analysed for a variety of parameters under the influence of a turbulence-induced channel fading, demonstrating the convergence behaviour of BICM-ID to enable the TWR-FSO PNC system, effectively mitigating the impact of the fading turbulence channel.

  2. 75 FR 57053 - Camas National Wildlife Refuge, Jefferson County, ID; Comprehensive Conservation Plan and...

    Science.gov (United States)

    2010-09-17

    ... Conservation Plan and Environmental Assessment AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of... prepare a comprehensive conservation plan (CCP) for Camas National Wildlife Refuge (refuge) in Hamer, ID... Refuge System, consistent with sound principles of fish and wildlife management, conservation,...

  3. nuID: a universal naming scheme of oligonucleotides for Illumina, Affymetrix, and other microarrays

    Directory of Open Access Journals (Sweden)

    Kibbe Warren A

    2007-05-01

    Full Text Available Abstract Background Oligonucleotide probes that are sequence identical may have different identifiers between manufacturers and even between different versions of the same company's microarray; and sometimes the same identifier is reused and represents a completely different oligonucleotide, resulting in ambiguity and potentially mis-identification of the genes hybridizing to that probe. Results We have devised a unique, non-degenerate encoding scheme that can be used as a universal representation to identify an oligonucleotide across manufacturers. We have named the encoded representation 'nuID', for nucleotide universal identifier. Inspired by the fact that the raw sequence of the oligonucleotide is the true definition of identity for a probe, the encoding algorithm uniquely and non-degenerately transforms the sequence itself into a compact identifier (a lossless compression. In addition, we added a redundancy check (checksum to validate the integrity of the identifier. These two steps, encoding plus checksum, result in an nuID, which is a unique, non-degenerate, permanent, robust and efficient representation of the probe sequence. For commercial applications that require the sequence identity to be confidential, we have an encryption schema for nuID. We demonstrate the utility of nuIDs for the annotation of Illumina microarrays, and we believe it has universal applicability as a source-independent naming convention for oligomers. Reviewers This article was reviewed by Itai Yanai, Rong Chen (nominated by Mark Gerstein, and Gregory Schuler (nominated by David Lipman.

  4. Epigenetic regulation of ID4 in the determination of the BRCAness phenotype in breast cancer.

    Science.gov (United States)

    Branham, M T; Campoy, E; Laurito, S; Branham, R; Urrutia, G; Orozco, J; Gago, F; Urrutia, R; Roqué, M

    2016-01-01

    BRCAness breast tumors represent a group of sporadic tumors characterized by a reduction in BRCA1 gene expression. As BRCA1 is involved in double-strand breaks (DSBs) repair, dysfunctional BRCA pathway could make a tumor sensitive to DNA damaging drugs (e.g., platinum agents). Thus, accurately identifying BRCAness could contribute to therapeutic decision making in patients harboring these tumors. The purpose of this study was to identify if BRCAness tumors present a characteristic methylation profile and/or were related to specific clinico-pathological features. BRCAness was measured by MLPA in 63 breast tumors; methylation status of 98 CpG sites within 84 cancer-related genes was analyzed by MS-MLPA. Protein and mRNA expressions of the selected genes were measured by quantitative real-time PCR and Western Blot. BRCAness was associated with younger age, higher nuclear pleomorphism, and triple-negative (TN) status. Epigenetically, we found that the strongest predictors for BRCAness tumors were the methylations of MLH1 and PAX5 plus the unmethylations of CCND2 and ID4. We determined that ID4 unmethylation correlated with the expression levels of both its mRNA and protein. We observed an inverse relation between the expressions of ID4 and BRCA1. To the best of our knowledge, this is the first report suggesting an epigenetic regulation of ID4 in BRCAness tumors. Our findings give new information of BRCAness etiology and encourage future studies on potential drug targets for BRCAness breast tumors.

  5. Espen Schaannings Foucault: Idéhistoriske intervensjoner i den norske Foucault-resepsjonen

    OpenAIRE

    Lillebø, Jonas Gamborg; Vik, Bjørnar Mortensen

    2009-01-01

    Artikkelen konsentrerer seg om et sentralt problem: Foucault som historiker og som filosof. Problemet aktualiseres ved en kritisk gjennomgang av Espen Schaannings lesing og formidling av Foucault som idéhistorisk intervenør. Er dette en for generaliserende lesning? Og er dette holdbart som en allmenn teori om historievitenskap?

  6. 76 FR 23321 - New Sweden Irrigation District, ID; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2011-04-26

    ... Energy Regulatory Commission New Sweden Irrigation District, ID; Notice of Preliminary Permit Application..., 2011, New Sweden Irrigation District filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the New...

  7. Validation of the Inventory of Depressive Symptomatology (IDS) in Cocaine Dependent Inmates.

    Science.gov (United States)

    Suris, Alina; Kashner, T. Michael; Gillaspy, James A., Jr.; Biggs, Melanie; Rush, A. John

    2001-01-01

    While the reliability and validity of Inventory of Depressive Symptomatology (IDS) scores have been established with outpatient adults being treated in community psychiatric clinics, it has not been used in special or dually diagnosed populations. Establishes internal consistency, concurrent validity, and construct validity for both the clinical…

  8. A Provably Secure Revocable ID-Based Authenticated Group Key Exchange Protocol with Identifying Malicious Participants

    Directory of Open Access Journals (Sweden)

    Tsu-Yang Wu

    2014-01-01

    Full Text Available The existence of malicious participants is a major threat for authenticated group key exchange (AGKE protocols. Typically, there are two detecting ways (passive and active to resist malicious participants in AGKE protocols. In 2012, the revocable identity- (ID- based public key system (R-IDPKS was proposed to solve the revocation problem in the ID-based public key system (IDPKS. Afterwards, based on the R-IDPKS, Wu et al. proposed a revocable ID-based AGKE (RID-AGKE protocol, which adopted a passive detecting way to resist malicious participants. However, it needs three rounds and cannot identify malicious participants. In this paper, we fuse a noninteractive confirmed computation technique to propose the first two-round RID-AGKE protocol with identifying malicious participants, which is an active detecting way. We demonstrate that our protocol is a provably secure AGKE protocol with forward secrecy and can identify malicious participants. When compared with the recently proposed ID/RID-AGKE protocols, our protocol possesses better performance and more robust security properties.

  9. Perspectives on the Role of Geo-Technologies for Addressing Contemporary Urban Issues: Implications for IDS

    NARCIS (Netherlands)

    Pfeffer, K.; Verrest, H.

    2016-01-01

    Contemporary patterns of urbanization come with many challenges regarding the quality of urban life, especially with respect to the provision of urban infrastructures and housing, exposure to environmental risks and urban inequalities. In International Development Studies (IDS) it is understood that

  10. Typing of Amerindian Kichwas and Mestizos from Ecuador with the SNPforID multiplex

    DEFF Research Database (Denmark)

    Poulsen, Lena; Børsting, Claus; Tomas, Carmen

    2011-01-01

    A total of 119 unrelated individuals from two of the major ethnic groups in Ecuador were typed for 49 of the autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex using the SNapShot® assay. Of the above, 42 samples originated from Mestizos (an admixed population) and the remaining...

  11. The Critical Role of the ID in Interactive Television: The Value of Immediacy.

    Science.gov (United States)

    Murphy, Karen L.; Farr, Charlotte W.

    The instructional designer (ID) plays a critical role in the development and viability of each course taught at a distance, particularly in the incorporation of immediacy behaviors, or communication behaviors that convey approachability and communicate interpersonal warmth and closeness. Faculty development must be fostered to encourage immediacy…

  12. Hizbollah lubab : "Me tahame ameeriklastega häid suhteid" / Mohamad Afif ; interv. Ivar Soopan

    Index Scriptorium Estoniae

    Afif, Mohamad

    2005-01-01

    Liibanoni shiiitide organisatsiooni Hizbollah meediasuhete direktor ütleb, et Hizbollah ei ole terroriorganisatsioon. Religioosse ja poliitilise grupina tahab Hizbollah häid suhteid teistega kõikjal maailmas, kuid probleem on poliitikas, selles, kuidas USA suhtub nende regiooni, tõekspidamistesse

  13. KorAP: the new corpus analysis platform at IDS Mannheim

    DEFF Research Database (Denmark)

    Banski, Piotr; Bingel, Joachim; Diewald, Nils

    2013-01-01

    The KorAP project (“Korpusanalyseplattform der nächste Generation”, “Corpus-analysis platform of the next generation”), carried out at the Institut für Deutsche Sprache (IDS) in Mannheim, Germany, has as its goal the development of a modern, state-of-the-art corpus-analysis platform, capable...

  14. 75 FR 22625 - Notice of Realty Action; Direct Sale of Public Land in Jerome County, ID

    Science.gov (United States)

    2010-04-29

    ... Bureau of Land Management Notice of Realty Action; Direct Sale of Public Land in Jerome County, ID AGENCY... for direct (non-competitive) sale to Todd and Bridget Buschhorn under the provisions of the Federal...: In order to ensure consideration in the environmental analysis of the proposed sale, comments must...

  15. 76 FR 29784 - Notice of Realty Action; Direct Sale of Public Lands in Jerome County, ID

    Science.gov (United States)

    2011-05-23

    ... Bureau of Land Management Notice of Realty Action; Direct Sale of Public Lands in Jerome County, ID... being proposed for direct sale to Todd and Bridget Buschhorn in accordance with Sections 203 and 209 of..., and is not needed for any other Federal purposes. The direct sale will allow for the subject parcel...

  16. 78 FR 39767 - Notice of Realty Action: Direct Sale of Public Land in Blaine County, ID

    Science.gov (United States)

    2013-07-02

    ... Bureau of Land Management Notice of Realty Action: Direct Sale of Public Land in Blaine County, ID AGENCY... proposed for direct sale to PORR in accordance with Sections 203 and 209 of the Federal Land Policy and... best be served by modified competitive bidding or direct (non-competitive) sale. In this instance,...

  17. 75 FR 71143 - Notice of Realty Action: Direct Sale of Public Land in Blaine County, ID

    Science.gov (United States)

    2010-11-22

    ... Bureau of Land Management Notice of Realty Action: Direct Sale of Public Land in Blaine County, ID AGENCY.... SUPPLEMENTARY INFORMATION: The following described public land is being proposed for direct sale to the Animal... Animal Shelter. Regulations contained in 43 CFR 2711.3-3 permit direct sales when a competitive sale...

  18. Coupling Molecular Modeling to the Traditional "IR-ID" Exercise in the Introductory Organic Chemistry Laboratory

    Science.gov (United States)

    Stokes-Huby, Heather; Vitale, Dale E.

    2007-01-01

    This exercise integrates the infrared unknown identification ("IR-ID") experiment common to most organic laboratory syllabi with computer molecular modeling. In this modification students are still required to identify unknown compounds from their IR spectra, but must additionally match some of the absorptions with computed frequencies they…

  19. Hizbollah lubab : "Me tahame ameeriklastega häid suhteid" / Mohamad Afif ; interv. Ivar Soopan

    Index Scriptorium Estoniae

    Afif, Mohamad

    2005-01-01

    Liibanoni shiiitide organisatsiooni Hizbollah meediasuhete direktor ütleb, et Hizbollah ei ole terroriorganisatsioon. Religioosse ja poliitilise grupina tahab Hizbollah häid suhteid teistega kõikjal maailmas, kuid probleem on poliitikas, selles, kuidas USA suhtub nende regiooni, tõekspidamistesse

  20. External validity of the Indonesian Wechsler Adult Intelligence Scale - Fourth edition (WAIS-IV-ID)

    NARCIS (Netherlands)

    Suwartono, C.; Hidajat, L.L.; Halim, M.S.; Hendriks, M.P.H.; Kessels, R.P.C.

    2016-01-01

    The Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV-ID) has been adapted and proved to be valid for its internal structure for Indonesian population. The same structure found as in the American WAIS-IV (WAIS-IV-US; Suwartono, Hendriks, Hidajat, Halim, & Kessels, 2015). Despite its strong i

  1. OpenID connect as a security service in Cloud-based diagnostic imaging systems

    Science.gov (United States)

    Ma, Weina; Sartipi, Kamran; Sharghi, Hassan; Koff, David; Bak, Peter

    2015-03-01

    The evolution of cloud computing is driving the next generation of diagnostic imaging (DI) systems. Cloud-based DI systems are able to deliver better services to patients without constraining to their own physical facilities. However, privacy and security concerns have been consistently regarded as the major obstacle for adoption of cloud computing by healthcare domains. Furthermore, traditional computing models and interfaces employed by DI systems are not ready for accessing diagnostic images through mobile devices. RESTful is an ideal technology for provisioning both mobile services and cloud computing. OpenID Connect, combining OpenID and OAuth together, is an emerging REST-based federated identity solution. It is one of the most perspective open standards to potentially become the de-facto standard for securing cloud computing and mobile applications, which has ever been regarded as "Kerberos of Cloud". We introduce OpenID Connect as an identity and authentication service in cloud-based DI systems and propose enhancements that allow for incorporating this technology within distributed enterprise environment. The objective of this study is to offer solutions for secure radiology image sharing among DI-r (Diagnostic Imaging Repository) and heterogeneous PACS (Picture Archiving and Communication Systems) as well as mobile clients in the cloud ecosystem. Through using OpenID Connect as an open-source identity and authentication service, deploying DI-r and PACS to private or community clouds should obtain equivalent security level to traditional computing model.

  2. The Id, Ego and Super-Ego in "Pride and Prejudice"

    Science.gov (United States)

    Liang, Yamin

    2011-01-01

    This paper mainly analyses the the id, ego, and super-ego which exists in the main character Elizabeth from several aspects, such as her pursuit for love, her prejudice towards Mr. Darcy, and the changes in her attitudes towards Wickham. This analysis helps readers appreciate this masterpiece from a different aspect which is related to the…

  3. System Virtualization and Efficient ID Transmission Method for RFID Tag Infrastructure Network

    CERN Document Server

    Kuribayashi, Shin-ichi

    2010-01-01

    The use of RFID tag which identifies a thing and an object will be expanded with progress of ubiquitous society, and it is necessary to study how to construct RFID network system as a social infrastructure like the Internet. First, this paper proposes the virtualization method of RFID tag network system to enable the same physical RFID network system to be used by multiple different service systems. The system virtualization not only reduces the system cost but also can dramatically reduce the installation space of physical readers and the operation cost. It is proposed that all equipments in the RFID network system except RFID tag could be shared with the conventional virtual technologies. Then, this paper proposes the conditional tag ID processing and the efficient tag ID transmission method which can greatly reduce the processing time and processing load in RFID tag Infrastructure network The conditional tag ID processing allows that tag ID is valid only at a certain time zone of day or in a certain area. ...

  4. 77 FR 56608 - Designation for the Pocatello, ID; Evansville, IN; and Salt Lake City, UT Areas

    Science.gov (United States)

    2012-09-13

    ... regarding the designation criteria in section 79(f) of the USGSA (7 U.S.C. 79(f)) and determined that Idaho... location and Designation Designation Official agency telephone start end Idaho Pocatello, ID (208) 233-8303... unless terminated by the Secretary; however, designations may be renewed according to the criteria...

  5. 77 FR 55813 - Transition of DOE-ID Public Reading Room

    Science.gov (United States)

    2012-09-11

    ... Library at 1776 Science Center Drive, Idaho Falls, ID 83401, beginning September 1, 2012. Access to documents will also be electronically accessible through the World Wide Web. For direction in accessing documents electronically through the World Wide Web, please refer to the Idaho Operations FOIA Web site...

  6. 76 FR 13976 - Eastern Idaho Resource Advisory Committee; Caribou-Targhee National Forest, Idaho Falls, ID

    Science.gov (United States)

    2011-03-15

    ... Forest Service Eastern Idaho Resource Advisory Committee; Caribou-Targhee National Forest, Idaho Falls, ID AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: Pursuant to the authorities in... Self-Determination Act of 2000 (Pub. L. 106-393) the Caribou-Targhee National Forests' Eastern Idaho...

  7. What's Going on in Your Professor's Head? Demonstrating the Id, Ego, and Superego

    Science.gov (United States)

    Segrist, Dan J.

    2009-01-01

    This article describes an in-class activity designed to demonstrate Freud's structural theory of the psyche, specifically the roles of the id, ego, and superego, as well as the interplay among them. Additionally, the activity visually illustrates Freud's ideas about the levels of consciousness associated with these 3 components. Pre-post quiz…

  8. OpenID Connect as a security service in cloud-based medical imaging systems.

    Science.gov (United States)

    Ma, Weina; Sartipi, Kamran; Sharghigoorabi, Hassan; Koff, David; Bak, Peter

    2016-04-01

    The evolution of cloud computing is driving the next generation of medical imaging systems. However, privacy and security concerns have been consistently regarded as the major obstacles for adoption of cloud computing by healthcare domains. OpenID Connect, combining OpenID and OAuth together, is an emerging representational state transfer-based federated identity solution. It is one of the most adopted open standards to potentially become the de facto standard for securing cloud computing and mobile applications, which is also regarded as "Kerberos of cloud." We introduce OpenID Connect as an authentication and authorization service in cloud-based diagnostic imaging (DI) systems, and propose enhancements that allow for incorporating this technology within distributed enterprise environments. The objective of this study is to offer solutions for secure sharing of medical images among diagnostic imaging repository (DI-r) and heterogeneous picture archiving and communication systems (PACS) as well as Web-based and mobile clients in the cloud ecosystem. The main objective is to use OpenID Connect open-source single sign-on and authorization service and in a user-centric manner, while deploying DI-r and PACS to private or community clouds should provide equivalent security levels to traditional computing model.

  9. Identification of clinical yeasts by Vitek MS system compared with API ID 32 C.

    Science.gov (United States)

    Durán-Valle, M Teresa; Sanz-Rodríguez, Nuria; Muñoz-Paraíso, Carmen; Almagro-Moltó, María; Gómez-Garcés, José Luis

    2014-05-01

    We performed a clinical evaluation of the Vitek MS matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) system with the commercial database version 2.0 for rapid identification of medically important yeasts as compared with the conventional phenotypic method API ID 32 C. We tested 161 clinical isolates, nine isolates from culture collections and five reference strains. In case of discrepant results or no identification with one or both methods, molecular identification techniques were employed. Concordance between both methods was observed with 160/175 isolates (91.42%) and misidentifications by both systems occurred only when taxa were not included in the respective databases, i.e., one isolate of Candida etchellsii was identified as C. globosa by Vitek MS and two isolates of C. orthopsilosis were identified as C. parapsilosis by API ID 32 C. Vitek MS could not identify nine strains (5.14%) and API ID 32 C did not identify 13 (7.42%). Vitek MS was more reliable than API ID 32 C and reduced the time required for the identification of clinical isolates to only a few minutes.

  10. Influência alelopática de hortelã (Mentha x villosa Huds.) sobre emergência de plântulas de alface (Lactuca sativa L.) Allelopathic influence of mint (Mentha x villosa Huds.) on the emergence of lettuce (Lactuca sativa L.) seedlings

    OpenAIRE

    Maia,J.T.L.S.; BONFIM,F.P.G.; Barbosa,C.K.R.; Guilherme,D.O.; Honório,I.C.G.; Martins,E. R.

    2011-01-01

    Objetivou-se com esse trabalho avaliar a interferência de possíveis efeitos alelopáticos de Mentha x villosa Huds. sobre a emergência de Lactuca sativa L. As atividades foram conduzidas em laboratório, no Instituto de Ciências Agrárias (ICA) da Universidade Federal de Minas Gerais, em Montes Claros/MG. Foram propostos três tratamentos, sendo esses: solo A, coletado em área cultivada com hortelã no horto medicinal do ICA/UFMG; solo B, coletado em áreas adjacentes e, testemunha (papel germitest...

  11. Événement, idéologie et utopie

    Directory of Open Access Journals (Sweden)

    Jean-Luc AMALRIC

    2014-12-01

    Full Text Available RESUMEL’hypothèse que tente d’esquisser cet article est que l’idée ricœurienne d’une médiatisation dynamique des contradictions de l’imaginaire social présuppose une corrélation originaire de l’idéologie et de l’utopie qui ne peut elle-même être comprise qu’à partir de l’événement de l’institution d’un imaginaire social constituant. Dans un premier temps, l’article s’efforce de cerner ce qui fait la spécificité de la théorie ricœurienne de l’idéologie et de l’utopie comme « pratiques imaginatives », en soulignant à ce titre l’influence déterminante des thèses de Jacques Ellul sur l’idéologie. Puis, dans un second temps, il s’engage dans une analyse régressive qui conduit de la réappropriation ricœurienne de la conception dialectique de l’idéologie et de l’utopie exposée par Mannheim à l’idée d’un fondement événementiel de ces deux formes opposées de l’imaginaire social.Mots-Clés : Evénement, idéologie, utopie, Ellul, Mannheim. ABSTRACTThis paper attempts to sketch out the hypothesis that the Ricœurian conception of a dynamic mediatization of the contradictions of the social imaginary presupposes an original correlation between ideology and utopia, which can itself be understood only from the event that institutes a constitutive social imaginary. The first part of the paper marks out the specificity of the Ricœurian theory of ideology and utopia in terms of “imaginative practices”, underlining the determining influence of Jacques Ellul’s theses on ideology. The second part tries to develop a regressive argument, starting from the Ricœurian re-appropriation of Mannheim’s dialectical conception of ideology and utopia, and leading back to the idea of an event foundation for these two opposed forms of the social imaginary.Keywords : Event, Ideology, Utopia, Ellul, Mannheim   

  12. [Identification of a novel mutation of IDS gene from a Chinese pedigree with MPS II].

    Science.gov (United States)

    GUO, Yi-Bin; PAN, Hong-Da; GUO, Chun-Miao; LI, Yong-Mei; CHEN, Lu-Ming

    2009-11-01

    The purpose of this study was to understand the molecular genetic mechanism of mucopolysaccharidosis type II (MPS II) and to provide a prerequisite for future prenatal gene diagnosis. A preliminary diagnosis was made by qualitative detection of Urinary Glycosaminoglycans of the suspected MPS II proband. Then, mutation detection was performed on the proband and his family members with PCR and direct sequencing of PCR products. After the novel mutation of c.876 del 2 in IDS gene was detected, sequence analysis was performed on exon 6 of IDS gene of the 135 cases, which consisted of 120 randomly selected normal controls, and other 15 patients with MPS I, IV, and VI other than MPS II. Besides, the patho-genicity of the novel mutation was analyzed with the following 2 methods: conservative analysis of the sequence of muta-tion spots of different species and the direct test of the IDS enzyme activity of the patient and his relative family members. The result of uroscopy of the proband was strong positive (GAGs +++). There was a novel deletion mutation of c.876-877 del TC in the coding region of exon 6 of IDS gene, which was a hemizygous mutation. However, the mutation of his mother and sister was a heterozygous mutation. Detection of the exon 6 of IDS gene showed that the mutation was not found among normal controls and other patients with MPS I, IV, and VI other than MPS II. Homology comparison of amino acid sequences from different species showed that the phenylalanine (F) glutamine (Q) of the mutation site of c.876-877 del TC located in p.292-293 was highly conserved. The activity of IDS enzyme of the proband was only 2.3 nmol/4 h/mL, which was much lower than normal; but the activity of IDS enzyme of his father, mother and sister was 641.9 nmol/4 h/mL, 95.8 nmol/4h/mL and 103.2 nmol/4h/mL, respectively. These results illustrated that the deletion and frame-shift mutation of c.876-877 del TC detected was a novel pathologic mutation, which was the underlying cause of

  13. ID3算法在ATM选点预测系统中的应用%Application of ID3 algorithm in ATM election prediction system

    Institute of Scientific and Technical Information of China (English)

    于海涛; 姚耀文

    2010-01-01

    ATM的应用日益广泛,如何部署一个利用率高的ATM已成为一个值得探讨的问题.运用数据挖掘知识和决策树ID3算法,可以对已经部署ATM的地区进行分析,从而找出高利用率ATM地区的特征,并建立ATM选点模型,作为金融机构在何处部署高效的ATM的参考.

  14. The regulation of matrix metalloproteinases by Id1 in gastric cancer%由Id1介导的MMP-2、MMP-9对胃癌生成的调控作用

    Institute of Scientific and Technical Information of China (English)

    雷婷; 韩霜; 郭雪艳; 丁杰

    2011-01-01

    Background and purpose: Angiogenesis is critical for the development of all malignancies.Id transcription factors have been shown to regulate key steps in tumor growth and metastasis due to their effects on angiogenesis.This study investigated the possible relationship between Id1 and matrix metalloproteinases (MMPs)in angiogenesis of gastric cancer.Methods: Expressions of Id1 and MMPs in gastric cancer tissues were examined by immunohistochemistry.The human gastric cancer SGC7901 sub-cell lines expressing Id1-siRNA was established.Expressions of MMP-2 and MMP-9 in Id1-siRNA transfectants were examined by semi-quantitative RT-PCR and Western blot.Enzyme activity of MMP-2 and MMP-9 in Id1-siRNA cells were detected by zymography method.Expressions of MMP-2 and MMP-9 in Id1-siRNA cell-transplanted tumor tissues in nude mice were identified by immunohistochemical method and Western blot.Results: Id1 and MMP-2, MMP-9 co-expressions were identified in the gastric cancer tissues.Significantly decreased expressions of both Id1 and MMP-2, MMP-9 on both protein and mRNA levels in SGC7901 Id1-siRNA transfectants were found.Data from zymography method showed that the activations of MMPs in Id1-siRNA cell lines were reduced compared to the control groups.Decreased expression of MMP-2 and MMP-9 in the Id1-siRNA transplanted tumor tissues in nude mice were found compared to those from the control cells.Conclusion: Id1 and MMP-2, MMP-9 were co-expressed in gastric cancer tissues; Id1 could upregulate the expression of MMP-2 and MMP-9 in gastric cancer.Downregulation of Id1 in the gastric cancer cells inhibited the transcriptional activities of MMP-2 and MMP-9.So we presumed that Id1 might promote tumorigenesis by transactivating MMP-2 and MMP-9 in gastric cancer.%背景与目的:肿瘤血管生成是肿瘤的一大重要特性,肿瘤微血管密度已被作为许多恶性肿瘤预后的一个重要指标.分化抑制因子(Id)是新近发现的与血管生成密切相关的分子.Id

  15. Determination of antimutagenic properties of apigenin-7-O-rutinoside, a flavonoid isolated from Mentha longifolia (L.) Huds. ssp. longifolia with yeast DEL assay.

    Science.gov (United States)

    Gulluce, Medine; Orhan, Furkan; Adiguzel, Ahmet; Bal, Tugba; Guvenalp, Zuhal; Dermirezer, Lutfiye Omur

    2013-07-01

    Lamiaceae is an important plant family that has been investigated for its medicinal properties due to its large amounts of phenolic acids and flavonoids. Flavonoids have been shown to have antioxidant and antimutagenic activities in different test systems, but their certain mechanisms are still unclear. This study was designed to evaluate the mutagenic and antimutagenic activities of apigenin 7-O-rutinoside, a flavonoid isolated from Mentha longifolia (L.) Huds. ssp. longifolia. The possible antimutagenic potential of apigenin 7-O-rutinoside (A7R) was examined against mutagens ethyl methanesulfonate (EMS) and acridine (AC) in a eukaryotic cell system Saccharomyces cerevisiae RS112. The results showed that A7R has different inhibition rates against EMS and AC-induced mutagenicity. Thus, the properties of A7R are of great pharmacological importance and might be beneficial for reducing the risk of reactive oxygen species-related diseases.

  16. Examining Trends and Coexisting Conditions Among Children Qualifying for SSI Under ADHD, ASD, and ID.

    Science.gov (United States)

    Pulcini, Christian D; Perrin, James M; Houtrow, Amy J; Sargent, John; Shui, Amy; Kuhlthau, Karen

    2015-01-01

    To examine the prevalence trends and coexisting conditions in attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID) in the pediatric Supplemental Security Income (SSI) population and general population. The Social Security Administration (SSA) provided data on primary and secondary diagnoses of children qualifying for SSI for years 2000 to 2011. We compared SSA data with 2000-2011 National Health Interview Survey data on the prevalence of mental health diagnoses among children in the general population living between 0 and 199% of the federal poverty line. We utilized linear regression analysis to test the statistical significance of differences in the trends of the conditions' prevalence. Over this time period, the SSI population experienced increases in ADHD (5.8%) and ASD (7.2%) and a decrease in ID (-10.3%). Comparison with change in the general population indicated no significant difference in ADHD but significant differences in ASD and ID. Relative percentage changes reflect similar changes. The SSI population qualifying for SSI with ADHD (70.8%) had higher rates of coexisting conditions than the general population (66.1%), but lower rates of coexisting conditions for ASD and ID. ADHD is on the rise among children receiving SSI and in the general population. This suggests that the rise of ADHD in the SSI population is expected and does not represent a misallocation of resources. Changes described among the SSI population in ASD and ID may allude to diagnostic/coding trends and/or true changes in prevalence. Limitations arise from the comparability of the 2 data sets. Copyright © 2015 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  17. Secure Single Sign-On using CAS and OpenID

    Directory of Open Access Journals (Sweden)

    Mihai Gabriel Ionita

    2012-09-01

    Full Text Available As the number of connected applications increases, user convenience makes them use the same password, which can create vulnerabilities in an organization’s infrastructure. Therefore, those with security concerns regarding these activities, conducted in the electronic environment, came to support the idea of ​​Single Sign-On systems, having the user in mind. This concept facilitates the authentication process to various resources available on the Internet, or locally, using a single pair of credentials, only once, so it makes the „one for all” password, the method of writing passwords on post-it’s glued to the monitor , or keeping them stored in unsecured text files, sent into oblivion. This paper aims to make a comprehensive analysis of the infrastructure of security and authentication systems on the market. On the other hand, the project presents the implementation of several open source solutions such as OpenID, NTLM in PHP or the Central Authentication Service. For the application that uses OpenID an online store that has an administration page, to which access is restricted using OpenID credentials, was further secured by filtering these IDs in a MySQL database to prevent access to anyone having a valid OpenID credential. For the demonstration of NTLM enabled SSO, another website is used in which access has been blocked to a page. For accessing the page, a valid Windows authentication credential is required. Both the online-shop and demonstration site for NTLM are written in PHP. In addition, the systems using them are implemented also using PHP. For implementing the CAS demo, two Tomcat servlets have been used for demonstration purposes, additional filtering being done by an ApacheDS server.

  18. FHL2 Interacts with and Acts as a Functional Repressor of Id2 in Human Neuroblastoma Cells

    Institute of Scientific and Technical Information of China (English)

    Wei-dong Han; Zhi-qiang Wu; Ya-li Zhao; Yi-ling Si; Xiao-bing Fu

    2009-01-01

    Objective: Id2 is a natural inhibitor of the basic helix-loop-helix(bHLH) transcription factors. Although it is well known that active Id2 prevents differentiation and promotes cell cycle progression and tumorigenesis, the molecular events that regulate Id2 activity remain to be investigated.Methods: Yeast two-hybrid, mammalian two-hybrid, GST-pulldown and immunoprecipitation (CoIP) assays were used to screen and identify novel Id2 interactors. Luciferase assays were used to detect E47-mediated transcription activity. Colony formation and BrdU incorporation assays were used to determine cellular proliferation abilities. Northorn blot, western blot and quantitative PCR methods were used to measure gene expression levels. Electrophoretic mobility shift assays (EMSAs) were performed to investigate protein/DNA binding.Results: The LIM-only protein FHL2 (four-and-a-half-LIM-only protein 2) was identified to be a novel Id2 interactor. The HLH domain within Id2 is not required for its interaction with FHL2. FHL2 antagonizes the inhibitory effect of Id2 on the basic helix-loop-helix protein E47-mediated transcription. FHL2 prevents the formation of Id2-E47 heterdimer, thus releasing E47 to its target DNA and restoring its transcriptional activity. FHL2 expression was remarkably up-regulated during retinoic acid-induced differentiation of neuroblastoma cells, during which the expression of Id2 is opposite to that. Ectopic FHL2 expression in neuroblastoma cells markedly reduces the transcriptional and cell-cycle promoting functions of Id2.Conclusion: These results indicate that FHL2 is an important repressor of the oncogenic activity of Id2 in neuroblastoma cells.

  19. Evaluation of the iPLEX(®) Sample ID Plus Panel designed for the Sequenom MassARRAY(®) system. A SNP typing assay developed for human identification and sample tracking based on the SNPforID panel

    DEFF Research Database (Denmark)

    Johansen, P; Andersen, J D; Børsting, Claus

    2013-01-01

    ) and Matrix Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS). In this study, we evaluated the accuracy and sensitivity of the iPLEX(®) Sample ID Plus Panel by comparing the typing results of the iPLEX(®) Sample ID Plus Panel with those obtained with our ISO 17025 accredited...

  20. [Comparison of Phoenix™ Yeast ID Panel and API® ID 32C commercial systems for the identification of Candida species isolated from clinical samples].

    Science.gov (United States)

    Gayibova, Ülkü; Dalyan Cılo, Burcu; Ağca, Harun; Ener, Beyza

    2014-07-01

    Opportunistic fungal pathogens are one of the important causes of nosocomial infections, and several different types of yeasts, especially Candida species are increasingly recovered from immunocompromised patients. Since many of the yeasts are resistant to the commonly used antifungal agents, the introduction of appropriate therapy depends on rapid and accurate identification. The aims of this study were to compare the commercial identification systems namely API® ID 32C (bioMerieux, France) and Phoenix™ Yeast ID Panel (Becton Dickinson Diagnostics, USA) for the identification of Candida species and to evaluate the effect of morphological findings in the identification process. A total of 211 yeast strains isolated from different clinical samples (111 urine, 34 blood/vascular catheter, 27 upper/lower respiratory tract, 16 abscess/pus, 13 throat/vagina swabs and 10 sterile body fluids) of 137 patients hospitalized in Uludag University Health and Research Center between October 2013 to January 2014, were included in the study. Samples were cultured on blood agar, chromogenic agar (CHROMagar Candida, BD, USA) and Saboraud's dextrose agar (SDA), and isolated yeast colonies were evaluated with germ tube test and morphological examination by microscopy on cornmeal/Tween-80 agar. The isolates were identified as well by two commercial systems according to the manufacturers' recommendations. Discrepant results between the systems were tried to be resolved by using morphological characteristics of the yeasts. Of the isolates 159 were identified identical by both of the systems, and the concordance between those systems were estimated as 75.4%. According to the concordant identification, the most frequently isolated species was C.albicans (44.1%) followed by C.tropicalis (9.9%), C.glabrata (9.5%), C.parapsilosis (8.5%) and C.kefyr (8.1%). The concordance rate was 81.7% in identification of frequently isolated species (C.albicans, C.tropicalis, C.parapsilosis, C.glabrata, C

  1. The {\\tt Mathematica} package {\\tt TopoID} and its application to the Higgs boson production cross section

    CERN Document Server

    Hoff, Jens

    2016-01-01

    We present the {\\tt Mathematica} package {\\tt TopoID} which aims at the automation of several steps in multiloop calculations. The algorithm which lies at the very core of the package is described and illustrated with an example. The main features of {\\tt TopoID} are stated and some of them are briefly demonstrated for NLO or NNLO Higgs boson production.

  2. 11 CFR 300.50 - Prohibited fundraising by national party committees (2 U.S.C. 441i(d)).

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Prohibited fundraising by national party committees (2 U.S.C. 441i(d)). 300.50 Section 300.50 Federal Elections FEDERAL ELECTION COMMISSION BIPARTISAN... Prohibited fundraising by national party committees (2 U.S.C. 441i(d)). (a) Prohibitions on fundraising...

  3. ID1 Is a Functional Marker for Intestinal Stem and Progenitor Cells Required for Normal Response to Injury

    Directory of Open Access Journals (Sweden)

    Ning Zhang

    2014-11-01

    Full Text Available LGR5 and BMI1 mark intestinal stem cells in crypt base columnar cells and +4 position cells, respectively, but characterization of functional markers in these cell populations is limited. ID1 maintains the stem cell potential of embryonic, neural, and long-term repopulating hematopoietic stem cells. Here, we show in both human and mouse intestine that ID1 is expressed in cycling columnar cells, +4 position cells, and transit-amplifying cells in the crypt. Lineage tracing revealed ID1+ cells to be self-renewing, multipotent stem/progenitor cells that are responsible for the long-term renewal of the intestinal epithelium. Single ID1+ cells can generate long-lived organoids resembling mature intestinal epithelium. Complete knockout of Id1 or selective deletion of Id1 in intestinal epithelium or in LGR5+ stem cells sensitizes mice to chemical-induced colon injury. These experiments identify ID1 as a marker for intestinal stem/progenitor cells and demonstrate a role for ID1 in maintaining the potential for repair in response to colonic injury.

  4. Initial Validation of the Chinese Quality of Life Questionnaire-Intellectual Disabilities (CQOL-ID): A Cultural Perspective

    Science.gov (United States)

    Wong, P. K. S.; Wong, D. F. K.; Schalock, R. L.; Chou, Y-C.

    2011-01-01

    Background: In the field of intellectual disabilities (ID), the quality of life concept has been developing rapidly in Chinese societies including Hong Kong, mainland China and Taiwan. However, there is a lack of locally validated instruments to measure the quality of life of people with ID. The study reported in this paper attempted to validate…

  5. Limited concordance between teachers, parents and healthcare professionals on the presence of chronic diseases in ID-adolescents

    NARCIS (Netherlands)

    Oeseburg, B.; Jansen, D. E. M. C.; Reijneveld, S. A.; Dijkstra, G. J.; Groothoff, J. W.

    2010-01-01

    Evidence on teachers' knowledge about somatic and mental chronic diseases among ID-adolescent compared to the knowledge parents and healthcare professionals have, is limited. The aim of this study is: (1) to assess the knowledge of teachers on the presence of chronic diseases in ID-adolescents; (2)

  6. Limited Concordance between Teachers, Parents and Healthcare Professionals on the Presence of Chronic Diseases in ID-Adolescents

    Science.gov (United States)

    Oeseburg, B.; Jansen, D. E. M. C.; Reijneveld, S. A.; Dijkstra, G. J.; Groothoff, J. W.

    2010-01-01

    Evidence on teachers' knowledge about somatic and mental chronic diseases among ID-adolescent compared to the knowledge parents and healthcare professionals have, is limited. The aim of this study is: (1) to assess the knowledge of teachers on the presence of chronic diseases in ID-adolescents; (2) to compare teachers with parents and healthcare…

  7. ACE I/D polymorphism is associated with mortality in a cohort study of patients starting with dialysis

    NARCIS (Netherlands)

    van der Sman-de Beer, F; Verhagen, C; Rombach, SM; Boorsma, P; van Manen, JG; Korevaar, JC; van den Bogaard, R; Boeschoten, EW; Krediet, RT; Navis, GJ; Vandenbroucke, JP; Dekker, FW

    2005-01-01

    ACE I/D polymorphism is associated with mortality in a cohort study of patients starting with dialysis. Background. In dialysis patients, only a few follow-up studies have addressed the relationship between the insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene and

  8. Quality assessment of IDS contribution to ITRF2014 performed by DGFI-TUM

    Science.gov (United States)

    Bloßfeld, Mathis; Seitz, Manuela; Angermann, Detlef; Moreaux, Guilhem

    2016-12-01

    The International DORIS Service (IDS) submitted input data for the most recent realization of the International Terrestrial Reference System (ITRS), the International Terrestrial Reference Frame 2014 (ITRF2014). As one of the ITRS Combination Centers, DGFI-TUM is in charge to analyze and assess the quality of the submitted data and to compute a combined global TRF solution (called DTRF2014) using observations of the four geodetic space techniques GNSS, VLBI, SLR and DORIS. The combination methodology used at DGFI-TUM is based on the combination of datum-free normal equations. Together with station coordinates and velocities, terrestrial pole coordinates are estimated in one common adjustment. The paper presents the analysis results of the most recent DORIS submission IDS-d09 and evaluates its quality w.r.t. the DTRF2008 (IDS-only) solution. In the most recent version of the analysis, we introduce in total 55 station discontinuities and reduce 15 stations due to a too short time span or too few observations. Time series of weekly IDS solutions are computed and validated w.r.t. DTRF2008. The transformation parameter time series and the station residuals are discussed in detail. Especially the scale parameter time series shows a significant improvement compared to the DTRF2008 input data. The scatter of the x- and y-translation is significantly reduced to 5.7 mm and 7.1 mm compared to 6.6 mm and 8.1 mm for the DTRF2008 (IDS-only) solution. The z-translation time series still shows a high correlation with solar activity. 10% of all station residuals are significantly affected by spectral peaks at draconitic period harmonics of the altimetry satellites Jason and TOPEX/Poseidon and up to 48% of all station residual time series contain significantly determined frequencies with a 14 day period. The multi-year IDS solution is validated w.r.t. DTRF2008 and the consistently estimated terrestrial pole coordinates are analyzed and compared to IERS 08 C04. The x-pole spectra

  9. A functionally significant polymorphism in ID3 is associated with human coronary pathology.

    Directory of Open Access Journals (Sweden)

    Ani Manichaikul

    Full Text Available We previously identified association between the ID3 SNP rs11574 and carotid intima-media thickness in the Diabetes Heart Study, a predominantly White diabetic population. The nonsynonymous SNP rs11574 results in an amino acid substitution in the C-terminal region of ID3, attenuating the dominant negative function of ID3 as an inhibitor of basic HLH factor E12-mediated transcription. In the current investigation, we characterize the association between the functionally significant polymorphism in ID3, rs11574, with human coronary pathology.The Multi-Ethnic Study of Atherosclerosis (MESA is a longitudinal study of subclinical cardiovascular disease, including non-Hispanic White (n = 2,588, African American (n = 2,560 and Hispanic (n = 2,130 participants with data on coronary artery calcium (CAC. The Coronary Assessment in Virginia cohort (CAVA included 71 patients aged 30-80 years, undergoing a medically necessary cardiac catheterization and intravascular ultrasound (IVUS at the University of Virginia. ID3 SNP rs11574 risk allele was associated with the presence of CAC in MESA Whites (P = 0.017. In addition, the risk allele was associated with greater atheroma burden and stenosis in the CAVA cohort (P = 0.003, P = 0.04 respectively. The risk allele remained predictive of atheroma burden in multivariate analysis (Model 1: covariates age, gender, and LDL, regression coefficient = 9.578, SE = 3.657, p = 0.0110; Model 2: covariates Model 1, presence of hypertension, presence of diabetes, regression coefficient = 8.389, SE = 4.788, p = 0.0163.We present additional cohorts that demonstrate association of ID3 SNP rs11574 directly with human coronary artery pathology as measured by CAC and IVUS: one a multiethnic, relatively healthy population with low levels of diabetes and the second a predominantly White population with a higher incidence of T2DM referred for cardiac catheterization.

  10. Regulatory substances produced by lymphocytes. V. Production of inhibitor of DNA synthesis (IDS) by proliferating T lymphocytes.

    Science.gov (United States)

    Namba, Y; Jegasothy, B V; Waksman, B H

    1977-04-01

    The conditions neccessary for production of inhibitor of DNA synthesis (IDS) by rat lymphocytes were investigated. In concanavalin A (Con A)-stimulated lymph node cell (LNC) cultures, IDS production was not detected in the culture supernatant during the first 24 hr, and it increased gradually after that to reach a maximum at 3 to 4 days. When the cells were pretreated with mitomycin C, IDS was not produced, suggesting that DNA synthesis of LNC or a LNC subpopulation is necessary for IDS production. In contrast, Con A-stimulated spleen cells priduced a high level of IDS within 24 hr, and its production fell off sharply thereafter. Con A-stimulated rat thymocytes also produced IDS reaching a maximum at 2 to 3 dyas. However, thymus cells from rats treated with hydrocortisone 48 hr previously did not produce IDS. This finding implies that cortisol-sensitive (cortical) thymocytes are capable of producing IDS and cortisol-resistant (medullary) thymocytes are not. IDS production by lymphoblasts was proportional to cell number and unaffected eith by cell density (1 to 10 x 106/ml) or by the concomitant presence of normal cells from spleen, lymph node, or thymus. Thus Con A-stimulated cells, after becoming blasts, appear to produce IDS automatically wihtout affecting or being affected by other cells. Both spleen and thymus cells from rats injected with a large dose of antigen (ovalbumin, 100 mg, i.p.) 24 hr in advance produced substantial amounts of IDS in culture within 24 hr in the absence of mitogen or additional antigen, but not the cells from rats injected with an immunizing dose (1 mg) of the same antigen. The cells producing IDS in the spleen were shown to be adherent to glass wool, and those in the thymus were partially so. IDS production by antigen-stimulated spleen cells was abrogated by injecting rats with bromodexyuridine (BUdR) at 0 and 12 hr after the ovalbumin. These findings suggest that a subpopulation ofadherent spleen cells (possibly resembling cortical

  11. Role of Leuconostoc mesenteroides in Leavening the Batter of Idli, a Fermented Food of India1

    Science.gov (United States)

    Mukherjee, S. K.; Albury, M. N.; Pederson, C. S.; Van Veen, A. G.; Steinkraus, K. H.

    1965-01-01

    The fermentation of the batter of idli, a fermented food of India, was studied. The microorganisms responsible for the characteristic changes in the batter were isolated and identified. Although there is a sequential change in the bacterial flora, the predominant microorganism responsible for souring, as well as for gas production, was found to be Leuconostoc mesenteroides. In the later stages of fermentation, growth of Streptococcus faecalis and, still later, of Pediococcus cerevisiae becomes significant. The fermentation of idli demonstrates a leavening action caused by the activity of the heterofermentative lactic acid bacterium, L. mesenteroides. As far as is known, this is the first record of a leavening action produced exclusively by the activity of a lactic acid bacterium. Images Fig. 3 PMID:14325884

  12. ORCID Integration: Services to Create and Use ORCID IDs at KAUST

    KAUST Repository

    Grenz, Daryl M.

    2015-06-09

    As ORCID IDs become accepted as a global standard, the potential benefits to researchers and institutions of making use of them are multiplying. At King Abdullah University of Science and Technology (KAUST) we adopted the first institutional open access policy in the Arab region in June 2014 and are integrating with ORCID as part of services to researchers that improve the preservation and dissemination of their research. We started by using ORCID IDs to identify authors in our institutional repository. Our next step was to join ORCID as an institutional member and then set up a plan to support our faculty, researchers and students in the creation and use of ORCID identifiers. This presentation will look at the choices made and lessons learned during this process, focusing on the tools we developed to interact with the ORCID member API and the ways in which introducing ORCID has complemented other repository initiatives, such as the implementation of our institutional open access policy.

  13. ID-TIMS Geochronology of ca 1 Ma leucogranites from the core of Nanga Parbat

    Science.gov (United States)

    Bowring, S. A.; Searle, M. P.; Waters, D. J.; Hodges, K. V.; Schmitz, M. D.; Crowley, J.

    2003-12-01

    Although isotope-dilution, themal-ioniaztion mass spectrometry (ID-TIMS) is the most precise method available for U-Th-Pb geochronology of accessory minerals, the technique is traditionally not applied to samples youger than ca. 10 Ma due to low concentrations of radiogenic Pb. However, recent analytical advances allow the routine measurement of less than 5-10 picograms of radiogenic Pb, and the reduction of laboratory blanks to extremely low levels. As a consequence, it is now possible to use ID-TIMS for U-Pb geochronology of very young accessory mineral suites to develop new insights regarding the time scales and patterns of inheritance, melt production, and segregation in collisional orogens. The Nanga Parbat syntaxis of the northwestern Himalaya has had a long and complex thermal history, but it is famous for the evidence it provides for extremely young (Nanga Parbat in less than 1 million years.

  14. PERFORMANCE EVALUATION OF C-FUZZY DECISION TREE BASED IDS WITH DIFFERENT DISTANCE MEASURES

    Directory of Open Access Journals (Sweden)

    Vinayak Mantoor

    2012-01-01

    Full Text Available With the ever-increasing growth of computer networks and emergence of electronic commerce in recent years, computer security has become a priority. Intrusion detection system (IDS is often used as another wall of protection in addition to intrusion prevention techniques. This paper introduces a concept and design of decision trees based on Fuzzy clustering. Fuzzy clustering is the core functional part of the overall decision tree development and the developed tree will be referred to as C-fuzzy decision trees. Distance measure plays an important role in clustering data points. Choosing the right distance measure for a given dataset is a non-trivial problem. In this paper, we study the performance of C-fuzzy decision tree based IDS with different distance measures. We analyzed the results of our study using KDD Cup 1999 data and compared the accuracy of the classifier with different distance measures.

  15. New Cryptanalysis of an ID-based Password Authentication Scheme using Smart Cards and Fingerprints

    Directory of Open Access Journals (Sweden)

    MING-JHENG LI

    2010-11-01

    Full Text Available In 2002, Lee, Ryu and Yoo proposed a fingerprint-based remote user authentication scheme using a smart card. Their scheme would strengthen system security by verifying the smart card owner’s fingerprint. In 2003, Kim, Lee and Yoo proposed two ID-based password authentication schemes without passwords or verification tables,with smart card and fingerprints. The proposed nonce-based and timestamp-based schemes can withstand message replay attacks. In addition, the schemes can withstand impersonation attack. In this paper, we will first review Kim et al.’s ID-based password authentication schemes. Next, we will show that Kim et al.’s scheme still has the disadvantage of being vulnerable to impersonation attack.

  16. OpenID, a Single Sign-On Solution for E-learning Applications

    Directory of Open Access Journals (Sweden)

    Felician Alecu

    2011-09-01

    Full Text Available The e-learning applications of today require a special focus on security. Distributed e- learning applications have several modules user can access using different clients (desktop or mobile. The same user has several accounts with different credentials. In this context, the SSO (Single Sign-On solutions become very attractive since the user has to log in once and can access all the needed resources without being prompted again for the username and password. Using the OpenID standard for e-learning Web-based applications is a good and reliable solution because it supports both URL and XRI identifiers. This paper presents the main characteristics of OpenID standard and how this standard could be implemented for a distributed, Web-based, e-learning application.

  17. ROLE OF LEUCONOSTOC MESENTEROIDES IN LEAVENING THE BATTER OF IDLI, A FERMENTED FOOD OF INDIA.

    Science.gov (United States)

    MUKHERJEE, S K; ALBURY, M N; PEDERSON, C S; VANVEEN, A G; STEINKRAUS, K H

    1965-03-01

    The fermentation of the batter of idli, a fermented food of India, was studied. The microorganisms responsible for the characteristic changes in the batter were isolated and identified. Although there is a sequential change in the bacterial flora, the predominant microorganism responsible for souring, as well as for gas production, was found to be Leuconostoc mesenteroides. In the later stages of fermentation, growth of Streptococcus faecalis and, still later, of Pediococcus cerevisiae becomes significant. The fermentation of idli demonstrates a leavening action caused by the activity of the heterofermentative lactic acid bacterium, L. mesenteroides. As far as is known, this is the first record of a leavening action produced exclusively by the activity of a lactic acid bacterium.

  18. Hacia una complementariedad del espacio de trabajo idóneo

    OpenAIRE

    Verdugo, Paula

    2015-01-01

    En este trabajo se muestra el Espacio de Trabajo Matemático (ETM) de referencia y el ETM Idóneo del docente relativo a la sucesión an=(1+1/n)n, la cual es de nuestro interés por ser estudiada tanto en la enseñanza secundaria como en la enseñanza universitaria. Para nuestro estudio se considera una parte teórica de la matemática (ETM de Referencia) y otra parte en donde el profesor muestra como enseñaría la sucesión (ETM idóneo), el cual realiza cursos en los primeros años de universidad. A...

  19. We.I.Pe: Web Identification of People using e-mail ID

    CERN Document Server

    Kuppusamy, K S

    2012-01-01

    With the phenomenal growth of content in the World Wide Web, the diversity of user supplied queries have become vivid. Searching for people on the web has become an important type of search activity in the web search engines. This paper proposes a model named "We.I.Pe" to identify people on the World Wide Web using e-mail Id as the primary input. The approach followed in this research work provides the collected information, based on the user supplied e-mail id, in an easier to navigate manner. The grouping of collected information based on various sources makes the result visualization process more effective. The proposed model is validated by a prototype implementation. Experiments conducted on the prototype implementation provide encouraging results

  20. SALINITY, HYDROSTATIC PRESSURE, TEMPERATURE, SIGMA-THETA and POTENTIAL TEMPERATURE profile data collected in the North Atlantic Ocean on the CYGNUS, HUDSON and PARIZEAU cruises CY98-079, HUD9877 and others as part of the GB project from 1993-10-12 to 1999-09-29 (NODC Accession 0104393)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104393 includes profile and physical data collected aboard the CYGNUS, HUDSON and PARIZEAU during cruises CY98-079, HUD9877, PAR93-032, PAR94-018,...

  1. Preparation of idli batter, its properties and nutritional improvement during fermentation.

    Science.gov (United States)

    Ghosh, Debasree; Chattopadhyay, Parimal

    2011-10-01

    Idli is a traditional fermented rice and black gram based food. Idli batter is prepared by soaking polished parboiled rice and decorticated black gram for 4 h at 30 ± 1 °C in water. The soaked mass was ground using a grinder with adequate amount of water. The blend ratios of 2:1, 3:1 and 4:1 (w/w) batter were allowed for fermentation for different periods with the addition of 2% (w/w) of salt. The rheology of the product was assessed using a Brookfield Viscometer having disc spindles. Shear stress values were in the range of 0.22 and 4 Pa and reached a maximum value at 7 h of fermentation. The density, pH, and percentage total acidity of batter during fermentation for different blend ratios ranged between 0.93 and 0.59 gm cm(-3), 4.21 and 5.9 and 0.44 and 0.91% respectively. During fermentation, maximum production of riboflavin and thiamine were found to be 0.76 mg/100 gm and 0.73 mg/100 gm in 3:1 blend ratio of idli batter; and the folic acid content was found to be at a maximum of 0.75 mg/100 gm of idli batter after 10 h of fermentation. Digestibility in terms of amino N2 content was analysed by formol titration.

  2. A non-parametric peak calling algorithm for DamID-Seq.

    Directory of Open Access Journals (Sweden)

    Renhua Li

    Full Text Available Protein-DNA interactions play a significant role in gene regulation and expression. In order to identify transcription factor binding sites (TFBS of double sex (DSX-an important transcription factor in sex determination, we applied the DNA adenine methylation identification (DamID technology to the fat body tissue of Drosophila, followed by deep sequencing (DamID-Seq. One feature of DamID-Seq data is that induced adenine methylation signals are not assured to be symmetrically distributed at TFBS, which renders the existing peak calling algorithms for ChIP-Seq, including SPP and MACS, inappropriate for DamID-Seq data. This challenged us to develop a new algorithm for peak calling. A challenge in peaking calling based on sequence data is estimating the averaged behavior of background signals. We applied a bootstrap resampling method to short sequence reads in the control (Dam only. After data quality check and mapping reads to a reference genome, the peaking calling procedure compromises the following steps: 1 reads resampling; 2 reads scaling (normalization and computing signal-to-noise fold changes; 3 filtering; 4 Calling peaks based on a statistically significant threshold. This is a non-parametric method for peak calling (NPPC. We also used irreproducible discovery rate (IDR analysis, as well as ChIP-Seq data to compare the peaks called by the NPPC. We identified approximately 6,000 peaks for DSX, which point to 1,225 genes related to the fat body tissue difference between female and male Drosophila. Statistical evidence from IDR analysis indicated that these peaks are reproducible across biological replicates. In addition, these peaks are comparable to those identified by use of ChIP-Seq on S2 cells, in terms of peak number, location, and peaks width.

  3. A non-parametric peak calling algorithm for DamID-Seq.

    Science.gov (United States)

    Li, Renhua; Hempel, Leonie U; Jiang, Tingbo

    2015-01-01

    Protein-DNA interactions play a significant role in gene regulation and expression. In order to identify transcription factor binding sites (TFBS) of double sex (DSX)-an important transcription factor in sex determination, we applied the DNA adenine methylation identification (DamID) technology to the fat body tissue of Drosophila, followed by deep sequencing (DamID-Seq). One feature of DamID-Seq data is that induced adenine methylation signals are not assured to be symmetrically distributed at TFBS, which renders the existing peak calling algorithms for ChIP-Seq, including SPP and MACS, inappropriate for DamID-Seq data. This challenged us to develop a new algorithm for peak calling. A challenge in peaking calling based on sequence data is estimating the averaged behavior of background signals. We applied a bootstrap resampling method to short sequence reads in the control (Dam only). After data quality check and mapping reads to a reference genome, the peaking calling procedure compromises the following steps: 1) reads resampling; 2) reads scaling (normalization) and computing signal-to-noise fold changes; 3) filtering; 4) Calling peaks based on a statistically significant threshold. This is a non-parametric method for peak calling (NPPC). We also used irreproducible discovery rate (IDR) analysis, as well as ChIP-Seq data to compare the peaks called by the NPPC. We identified approximately 6,000 peaks for DSX, which point to 1,225 genes related to the fat body tissue difference between female and male Drosophila. Statistical evidence from IDR analysis indicated that these peaks are reproducible across biological replicates. In addition, these peaks are comparable to those identified by use of ChIP-Seq on S2 cells, in terms of peak number, location, and peaks width.

  4. 集装箱编码图像的识别%Container Image ID Recognition

    Institute of Scientific and Technical Information of China (English)

    朱秋煜; 韩锦成; 阚伟

    2000-01-01

    The paper studies a technique of container image ID recognition. In the image preprocessing phase, thresholdiong based on histogram and adaptive thresholding is used. In the character segmentation phase, a labeling method is used, which is based on connected region, location of character block, location of character line recovery of absent and fragmented characters. In the recognition phase, adaptive template match and multiple image results synthesis are used. A high recognition rate is obtained.

  5. 集装箱编码图像的识别%Container Image ID Recognition

    Institute of Scientific and Technical Information of China (English)

    朱秋煜; 韩锦成; 阚伟

    2001-01-01

    The paper studies a technique of container image ID recognition. In the image preprocessing phase, thresholdiong based on histogram and adaptive thresholding is used. In the character segmentation phase, a labeling method is used, which is based on connected region, location of character block, location of character line recovery of absent and fragmented characters. In the recognition phase, adaptive template match and multiple image results synthesis are used. A high recognition rate is obtained.

  6. Secure and trustworthy file sharing over cloud storage using eID tokens

    OpenAIRE

    Duarte, E; Pinheiro, F; Zúquete, A.; Gomes, H.

    2015-01-01

    This paper presents a multi-platform, open-source application that aims to protect data stored and shared in existing cloud storage services. The access to the cryptographic material used to protect data is implemented using the identification and authentication functionalities of national electronic identity (eID) tokens. All peer to peer dialogs to exchange cryptographic material is implemented using the cloud storage facilities. Furthermore, we have included a set of mechanisms to prevent ...

  7. SIMULASI SAHAM BERBASIS WEB DENGAN TEKNOLOGI VIRTUAL PRIVATE NETWORK DI PORTAL WWW.KONTAN.CO.ID

    Directory of Open Access Journals (Sweden)

    Albert Verasius Dian Sano

    2011-11-01

    forwarded through an official data vendor PT XYZ. Data from the IDX will be captured by a middleware application at PT XYZ and forwarded to www.kontan.co.id. This application has been tested and successfully run by around 700 users. This tool is expected to provide a kind of education and motivation to beginner-level investors who want to be engaged with the stock-trading activities.

  8. Torma ringtallist jäid vaid müürid / Bianca Mikovitš

    Index Scriptorium Estoniae

    Mikovitš, Bianca

    2011-01-01

    Pärast 29. aprillil 2011 toimunud tulekahju jäid Torma mõisa muinsuskaitse all olevast ringtallist järele vaid müürid. Muinsuskaitseameti Jõgevamaa vaneminspektori Sille Raidvere hinnangul päästaks Torma ringtalli lõplikust hävingust hoone müüride kiire konserveerimine, mis annaks edaspidiseks võimaluse tallihoone taastada

  9. Hester Prynne:the Commendable Balance of Id, Ego and Superego

    Institute of Scientific and Technical Information of China (English)

    佴欣欣; 李千

    2014-01-01

    Hester Prynne, the central character in The Scarlet Letter, is the ultimate example of sin in the eyes of Puritans. Howev-er, she finally manages to rewrite the meaning of scarlet letter"A". Through the lenses of Sigmund Freud’id, ego, and superego, it will be demonstrated that how she succeeds in balancing these three psychological elements, and making her spiritual develop-ment and transformation.

  10. The angiotensin converting enzyme gene i/d polymorphism in ellite polish and lithuanian judo players

    Directory of Open Access Journals (Sweden)

    J Eider

    2010-06-01

    Full Text Available A common polymorphism in the angiotensin converting enzyme I gene (the ACE I/D variant represents one of the first characterized and the most widely studied genetic variants in the context of elite athletes status and performance related traits. The aim of this study is to perform preliminary studies to analyze the possible importance of the ACE gene polymorphisms in elite Polish and Lithuanian judo players and sedentary individuals representing the possible relationships with genotype and physical performance. 28 male of elite Polish and Lithuania judo players were recruited for this study. For controls samples were prepared from 115 unrelated volunteers. DNA was extracted from the buccal cells donated by the subjects, and the PCR amplification of the polymorphic region of ACE gene contained either the insertion (I or deletion (D fragment was performed. Compared with sedentary controls, the frequency of I allele differ significantly from that found in judo player’s group: 60.7% vs. 44.3%(p=0.02 and ACE genotype frequency amongst the whole athletes group (28.6% II, 64.3% ID, 7.1% DD was also different from expected values (control group 19.1% II, 50.4% ID, 30.4% DD; p=0.019. Our investigation have proved the ACE I/D allele could be one of the factors influencing the elite endurance exercise performance. The research suggests that those most predisposed to judo are individuals with the allele distribution in the ACE gene that is most significant with regard to the duration of a fight, and not with regard to the character of the performed moves, as could be supposed.

  11. Evaluation of the Organon-Teknika MICRO-ID LISTERIA system.

    Science.gov (United States)

    Bannerman, E; Yersin, M N; Bille, J

    1992-06-01

    The MICRO-ID LISTERIA system, designed to identify Listeria isolates to species level within 24 h, was compared with conventional biochemical identification. MICRO-ID LISTERIA used in combination with the CAMP test correctly identified 409 (98.8%) of 414 strains isolated from human, animal, food, and environmental sources belonging to the seven species currently defined within the genus Listeria. The kit was easy to use and simple to interpret. However, 8 of the 15 tests (i.e., phenylalanine deaminase, hydrogen sulfide, indole, ornithine decarboxylase, lysine decarboxylase, malonate, urease, and o-nitrophenyl-beta-D-galactopyranoside) were considered superfluous for the differentiation of Listeria spp. The CAMP test was indispensable when using the MICRO-ID LISTERIA system, in particular to differentiate CAMP test-positive L. monocytogenes from the nonhemolytic, rhamnose-positive L. innocua. The hemolytic L. seeligeri and L. ivanovii strains and the nonhemolytic, non-rhamnose-acidifying L. welshimeri strains could also be differentiated from one another only on the basis of their CAMP test results. The very few strains of L. grayi and L. murrayi were easily differentiated from the other nonhemolytic species. Catalase-negative cocci should not be tested, because 12 out of 19 catalase-negative strains (all enterococci) in our test were misidentified as Listeria spp. The MICRO-ID LISTERIA system identified strains within 18 to 24 h and is thus less time-consuming than conventional tests. The system could, therefore, be used together with correctly done CAMP tests for the rapid identification of Listeria isolates, especially food and environmental isolates, for which rapid species differentiation is important.

  12. 基于计算模型的 OpenID Connect协议认证性的自动化分析%Automatic Analysis of Authentication of OpenID Connect Protocol Based on the Computational Model

    Institute of Scientific and Technical Information of China (English)

    孟博; 张金丽; 鲁金钿

    2016-01-01

    In this paper , we get the message term of OpenID Connect by analyzing its authentication message flow , model it with Blanchet calculus in computational model , and use the automatic verification tool CryptoVerif to analyze its authentication .The result shows that , in OpenID Connect protocol , Client can authenticate Token Endpoint , while there is no authentication between the End-User and Authorization Server , and Token Endpoint can′t authenticate Client .Finally, the solutions for the problem of no authentication in OpenID Connect protocol are presented .%分析了OpenID Connect 协议的消息结构,基于计算模型应用Blanchet 演算对OpenID Connect 协议进行了形式化建模,应用自动化验证工具CryptoVerif 验证了其认证性。结果表明:在OpenID Connect 协议中,客户端能够认证终端用户,但是终端用户与授权服务器之间不能相互认证、令牌终端不能认证客户端。为此,给出了OpenID Connect协议中不具有认证性问题的解决方法。

  13. ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation.

    Science.gov (United States)

    Morton, Derrick J; Patel, Divya; Joshi, Jugal; Hunt, Aisha; Knowell, Ashley E; Chaudhary, Jaideep

    2017-01-10

    Given that mutated p53 (50% of all human cancers) is over-expressed in many cancers, restoration of mutant p53 to its wild type biological function has been sought after as cancer therapy. The conformational flexibility has allowed to restore the normal biological function of mutant p53 by short peptides and small molecule compounds. Recently, studies have focused on physiological mechanisms such as acetylation of lysine residues to rescue the wild type activity of mutant p53. Using p53 null prostate cancer cell line we show that ID4 dependent acetylation promotes mutant p53 DNA-binding capabilities to its wild type consensus sequence, thus regulating p53-dependent target genes leading to subsequent cell cycle arrest and apoptosis. Specifically, by using wild type, mutant (P223L, V274F, R175H, R273H), acetylation mimics (K320Q and K373Q) and non-acetylation mimics (K320R and K373R) of p53, we identify that ID4 promotes acetylation of K373 and to a lesser extent K320, in turn restoring p53-dependent biological activities. Together, our data provides a molecular understanding of ID4 dependent acetylation that suggests a strategy of enhancing p53 acetylation at sites K373 and K320 that may serve as a viable mechanism of physiological restoration of mutant p53 to its wild type biological function.

  14. Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4.

    Science.gov (United States)

    Ren, Yin; Cheung, Hiu Wing; von Maltzhan, Geoffrey; Agrawal, Amit; Cowley, Glenn S; Weir, Barbara A; Boehm, Jesse S; Tamayo, Pablo; Karst, Alison M; Liu, Joyce F; Hirsch, Michelle S; Mesirov, Jill P; Drapkin, Ronny; Root, David E; Lo, Justin; Fogal, Valentina; Ruoslahti, Erkki; Hahn, William C; Bhatia, Sangeeta N

    2012-08-15

    The comprehensive characterization of a large number of cancer genomes will eventually lead to a compendium of genetic alterations in specific cancers. Unfortunately, the number and complexity of identified alterations complicate endeavors to identify biologically relevant mutations critical for tumor maintenance because many of these targets are not amenable to manipulation by small molecules or antibodies. RNA interference provides a direct way to study putative cancer targets; however, specific delivery of therapeutics to the tumor parenchyma remains an intractable problem. We describe a platform for the discovery and initial validation of cancer targets, composed of a systematic effort to identify amplified and essential genes in human cancer cell lines and tumors partnered with a novel modular delivery technology. We developed a tumor-penetrating nanocomplex (TPN) that comprised small interfering RNA (siRNA) complexed with a tandem tumor-penetrating and membrane-translocating peptide, which enabled the specific delivery of siRNA deep into the tumor parenchyma. We used TPN in vivo to evaluate inhibitor of DNA binding 4 (ID4) as a novel oncogene. Treatment of ovarian tumor-bearing mice with ID4-specific TPN suppressed growth of established tumors and significantly improved survival. These observations not only credential ID4 as an oncogene in 32% of high-grade ovarian cancers but also provide a framework for the identification, validation, and understanding of potential therapeutic cancer targets.

  15. The ID93 tuberculosis vaccine candidate does not induce sensitivity to purified protein derivative.

    Science.gov (United States)

    Baldwin, Susan L; Reese, Valerie; Granger, Brian; Orr, Mark T; Ireton, Gregory C; Coler, Rhea N; Reed, Steven G

    2014-09-01

    The tuberculin skin test (TST) is a simple and inexpensive test to determine whether individuals have been exposed to Mycobacterium tuberculosis. This test is not always reliable, however, in people previously immunized with BCG and/or who have been exposed to environmental mycobacterial species due to a reaction to purified protein derivative (PPD) used in the skin test. An issue with BCG, therefore, is that the resulting sensitization to PPD in some individuals compromises the diagnostic use of the skin test. The ability to induce protective immune responses without sensitizing to the tuberculin skin test will be important properties of next-generation tuberculosis (TB) vaccine candidates. We show here that guinea pigs immunized with the candidate TB vaccine ID93/GLA-SE, currently in clinical trials, do not react to intradermal PPD administration. In contrast, positive DTH responses to both ID93 and components thereof were induced in ID93/GLA-SE-immunized animals, indicating robust but specific cellular responses were present in the immunized animals. Noninterference with the TST is an important factor for consideration in the development of a vaccine against M. tuberculosis. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  16. A new improved ID-based proxy ring signature scheme from bilinear pairings

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Ring signature and proxy signature are of vital importance to secure electronic commerce. Recently,the bilinear pairing such as Weil pairing or Tate pairing on elliptic curves and hyperelliptic curves is playing an important role in security solutions. Several ID-based signature schemes have been put forward, many of which are based on bilinear pairings. In key management and moderate security demand scenarios, ID-based public key cryptosystem is more preferable than other public key infrastructure based systems. In this paper, an improved ID-based proxy ring signature scheme from bilinear pairings is proposed which combines the advantages of proxy signature and of ring signatures. Our scheme can guarantee the profits of the proxy signer via preventing the original signer form generating the proxy ring signature. Furthermore, bilinear pairings are introduced to minimize the computation overhead and to improve the related performance of our scheme. In contrast with Zhang's scheme, our scheme is a computational efficiency improvement for signature verification because the computational cost of bilinear pairings required is reduced from O(n) to O( 1 ). In addition, the proxy ring signature presented in this paper can perfectly satisfy all the security requirements of proxy ring signature, i.e.signer-ambiguity, non-forgeability, verification, non-deniability and distinguishability.

  17. Towards fraud-proof ID documents using multiple data hiding technologies and biometrics

    Science.gov (United States)

    Picard, Justin; Vielhauer, Claus; Thorwirth, Niels

    2004-06-01

    Identity documents, such as ID cards, passports, and driver's licenses, contain textual information, a portrait of the legitimate holder, and eventually some other biometric characteristics such as a fingerprint or handwritten signature. As prices for digital imaging technologies fall, making them more widely available, we have seen an exponential increase in the ease and the number of counterfeiters that can effectively forge documents. Today, with only limited knowledge of technology and a small amount of money, a counterfeiter can effortlessly replace a photo or modify identity information on a legitimate document to the extent that it is very diffcult to differentiate from the original. This paper proposes a virtually fraud-proof ID document based on a combination of three different data hiding technologies: digital watermarking, 2-D bar codes, and Copy Detection Pattern, plus additional biometric protection. As will be shown, that combination of data hiding technologies protects the document against any forgery, in principle without any requirement for other security features. To prevent a genuine document to be used by an illegitimate user,biometric information is also covertly stored in the ID document, to be used for identification at the detector.

  18. Quand l’idée fixe se met « à table »

    Directory of Open Access Journals (Sweden)

    Cécile de Bary

    2008-03-01

    Full Text Available Un livre de cuisine, comme A table de Claudian, édité en 1963, peut relever de la prose d’idées dans la mesure où son projet est sous-tendu par une idéologie très précise, qui seule lui donne sa cohérence. Si l’ethnocentrisme consiste à ne pas reconnaître à l’autre une culture, par exemple, ce livre apparaît comme ethnocentrique, puisqu’il a pour projet de départager les peuples qui savent et ceux qui ne savent pas. Il est encore réactionnaire, voué au rétablissement des savoir-faire des terroirs, contre les corruptions parisiennes en particulier. Dès lors, la présentation d’un plat est toujours susceptible de s’étendre ou de se faire discours, sous la poussée d’un lyrisme acrimonieux. Pour autant, il ne s’agit pas d’un faux livre de cuisine, d’un traité ou d’une « physiologie ». La recette est l’aboutissement logique de l’idée fixe. Elle est le lieu d’une bataille que l’argumentation sert, qu’elle met en scène et qu’elle prépare.

  19. DNA origami-based shape IDs for single-molecule nanomechanical genotyping

    Science.gov (United States)

    Zhang, Honglu; Chao, Jie; Pan, Dun; Liu, Huajie; Qiang, Yu; Liu, Ke; Cui, Chengjun; Chen, Jianhua; Huang, Qing; Hu, Jun; Wang, Lianhui; Huang, Wei; Shi, Yongyong; Fan, Chunhai

    2017-04-01

    Variations on DNA sequences profoundly affect how we develop diseases and respond to pathogens and drugs. Atomic force microscopy (AFM) provides a nanomechanical imaging approach for genetic analysis with nanometre resolution. However, unlike fluorescence imaging that has wavelength-specific fluorophores, the lack of shape-specific labels largely hampers widespread applications of AFM imaging. Here we report the development of a set of differentially shaped, highly hybridizable self-assembled DNA origami nanostructures serving as shape IDs for magnified nanomechanical imaging of single-nucleotide polymorphisms. Using these origami shape IDs, we directly genotype single molecules of human genomic DNA with an ultrahigh resolution of ~10 nm and the multiplexing ability. Further, we determine three types of disease-associated, long-range haplotypes in samples from the Han Chinese population. Single-molecule analysis allows robust haplotyping even for samples with low labelling efficiency. We expect this generic shape ID-based nanomechanical approach to hold great potential in genetic analysis at the single-molecule level.

  20. ID-based Signcryption Scheme%基于身份的签密方案

    Institute of Scientific and Technical Information of China (English)

    李虓; 何明星; 罗大文

    2009-01-01

    现有基于身份的签密方案存在签密不能被公开验证、签密能被伪造和签密不具有健壮性等缺陷.分析LHL方案的安全性,利用双线性对提出一个基于身份的签密方案,该方案能保证签密具有公开验证性、不可伪造性、健壮性、不可否认性和前向安全性,它只需要4个对运算,其效率高于其他慕于身份的签密方案.%The existing ID-based signcryption schemes have some drawbacks, such as the signcryption can not be public verified, the signcryption can be forged, the signcryption is not robust, and etc. This paper analyzes the security of the LHL scheme and adopts the bilinear parings to propose an ID-based signcryption scheme. This scheme can ensure the signcryption has some characters, such as public verifiability, unforgeability, robustness, non-repudiation and forward security. It only needs four pairs of operation and it is more efficient than other ID-based signcryption schemes.

  1. An ID/Locator Separation Based Group Mobility Management in Wireless Body Area Network

    Directory of Open Access Journals (Sweden)

    Moneeb Gohar

    2015-01-01

    Full Text Available Mobility management in wireless sensor network is the most important factor to be considered for applications such as healthcare system. Recently, Identifier (ID/Locator (LOC separation based mobility management scheme has been proposed for wireless sensor network. However, it does not perform well in group-based mobility management in wireless body area network, and thus it tends to induce large registration, packet delivery, and handover delays. To overcome these limitations, we propose a group-based mobility management scheme based on ID/LOC separation concept for ID-based communications with location-based routing to reduce the number of control messages. In the proposed scheme, each sensor device has a globally unique device identifier (GDID which contains the information of its home network domain. For handover support, each access gateway maintains its home GDID register (HGR and visiting GDID register (VGR which are used to keep the GDID-locator (LOC mappings for primary mobile devices in the distributed manner. Besides, in the proposed scheme, only the coordinator will send Router Solicitation and Router Advertisement messages to reduce the control messages further. By numerical analysis, we show that the proposed scheme can significantly reduce the registration, packet delivery, and handover delays, compared to the existing schemes.

  2. ACE insertion/deletion (I/D) polymorphism and diabetic nephropathy.

    Science.gov (United States)

    Rahimi, Zohreh

    2012-10-01

    Angiotensin converting enzyme (ACE) gene encodes ACE, a key component of renin angiotensin system (RAS), plays an important role in blood pressure homeostasis by generating the vasoconstrictor peptide angiotensin II. Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched. The presence of ACE insertion/deletion (I/D) polymorphism affects the plasma level of ACE. ACE DD genotype is associated with the highest systemic and renal ACE levels compared with the lowest ACE activity in carriers of II genotype. In this review focus has been performed on the study of ACE I/D polymorphism in various populations and its influence on the risk of onset and progression of diabetic nephropathy. Also, association between ACE I/D polymorphism and response to ACE inhibitor and angiotensin II receptor antagonists will be reviewed. Further, synergistic effect of this polymorphism and variants of some genes on the risk of development of diabetic nephropathy will be discussed.

  3. ZigID: Improving visibility in industrial environments by combining WSN and RFID

    Institute of Scientific and Technical Information of China (English)

    Pablo GARCIA ANSOLA; Andrés GARCIA; Javier de las MORENAS; Javier GARCIA ESCRIBANO; Francisco Javier OTAMENDI

    2011-01-01

    The objective of this work is to provide decision-making processes with an updated/real picture of the mobile resources in industrial environments through a constant feedback of information.The combination of identification technologies and wireless sensor networks(WSN)is proposed as a key development to guarantee an accurate and timely supply of online information regarding the localization and tracking of the mobile wireless devices.This approach uses a cooperative and distributed localization system,called ZigID,which is a WSN based on a Zigbee network with radio frequency identification(RFID)active tags as end nodes.The WSN can recover not only the ID information stored at the tags attached to mobile resources,but also any other useful data captured by specific sensors for acceleration,temperature,humidity and fuel status.This paper also shows the development of ZigID,including devices and information flows,as well as its implementation in ground handling operations at the Ciudad Real Central Airport,Spain.

  4. Is there an ACE ID - ACTN3 R577X polymorphisms interaction that influences sprint performance?

    Science.gov (United States)

    Eynon, N; Alves, A J; Yamin, C; Sagiv, M; Duarte, J A; Oliveira, J; Ayalon, M; Goldhammer, E; Sagiv, M; Meckel, Y

    2009-12-01

    Functional R577X (rs.1815739) and ID (rs.5186) polymorphisms in the alpha-actinin-3 ( ACTN3) and the angiotensin converting enzyme (ACE) genes, respectively, have been associated with sprint performance. The aim of this study was to determine their effect on sprint performance among 81 Israeli sprinters and 240 healthy controls. Results revealed that the ACE II genotype+ ACTN3 R allele (P=0.003 for sprinters vs. controls), and the ACTN3 RR genotype +ACE I allele (P=0.001 for sprinters vs. controls) might be the genotype for sprinters. In the whole cohort the probability of ACTN3 RR genotype+ ACE I allele being a sprinter (odds ratio 2.67, 95% confidence interval 1.45-4.93) and of ACE II genotype+ ACTN3 R allele being a sprinter (odds ratio 3.57, 95% confidence interval 1.78-7.15) was significantly higher than that in the controls. In conclusion, the above data suggest that ACE ID/ ACTN3 R577X genotype combination is associated with sprint ability. However, ACE ID/ ACTN3 R577X genotype combination is not related to the level of performance.

  5. Identifying IDS Agent Nodes Based on 3-Layered Key Management Framework for MANET

    Directory of Open Access Journals (Sweden)

    Marjan KUCHAKI RAFSANJANI

    2014-02-01

    Full Text Available Nowadays, Mobile Ad Hoc Networks (MANETs have become one of the most important networks in advanced technologies. However, MANETs are more vulnerable than wired and wireless networks to active and passive attacks. So, security and intrusion detection are very important in these networks. In this paper, we have presented a method of identifying IDS agent nodes in MANET. Whereas, IDS agent nodes due to monitoring activities in Intrusion Detection Systems (IDSs need more battery energy than other nodes in the network. In the first step, our method uses a 3-layered key management framework in order to authenticate and then in the second step, nodes with higher battery power from among authorized nodes as IDS agent nodes are considered. Therefore, with this method, some authorized nodes contribute in monitoring activities and the network lifetime will be increased and also communication cost in the 3-layered key management framework is less than other frameworks, thus communication performance will be increased.doi:10.14456/WJST.2014.30

  6. Evaluation of the iPLEX(®) Sample ID Plus Panel designed for the Sequenom MassARRAY(®) system. A SNP typing assay developed for human identification and sample tracking based on the SNPforID panel

    DEFF Research Database (Denmark)

    Johansen, P; Andersen, J D; Børsting, Claus;

    2013-01-01

    Sequenom launched the first commercial SNP typing kit for human identification, named the iPLEX(®) Sample ID Plus Panel. The kit amplifies 47 of the 52 SNPs in the SNPforID panel, amelogenin and two Y-chromosome SNPs in one multiplex PCR. The SNPs were analyzed by single base extension (SBE...... SNPforID assay. The average call rate for duplicate typing of any one SNPs in the panel was 90.0% when the mass spectra were analyzed automatically with the MassARRAY(®) TYPER 4.0 genotyping software in real time. Two reproducible inconsistencies were observed (error rate: 0.05%) at two different SNP...

  7. The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells.

    Science.gov (United States)

    Egusa, Hiroshi; Doi, Masanori; Saeki, Makio; Fukuyasu, Sho; Akashi, Yoshihiro; Yokota, Yoshifumi; Yatani, Hirofumi; Kamisaki, Yoshinori

    2011-08-01

    Small molecule compounds that potently affect osteoclastogenesis could be useful as chemical probes for elucidating the mechanisms of various biological phenomena and as effective therapeutic strategies against bone resorption. An osteoclast progenitor cell-based high-throughput screening system was designed to target activation of NFAT, which is a key event for osteoclastogenesis. Orphan ligand library screening using this system identified the β-carboline derivative harmine, which is a highly potent inhibitor of dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A), to be an NFAT regulator in osteoclasts. RAW264.7 cells highly expressed DYRK1A protein, and in vitro phosphorylation assay demonstrated that harmine directly inhibited the DYRK1A-mediated phosphorylation (in-activation) of NFATc1. Harmine promoted the dephosphorylation (activation) of NFATc1 in RAW264.7 cells within 24h, and it significantly increased the expression of NFATc1 in RAW264.7 cells and mouse primary bone marrow macrophages (BMMs) both in the presence and absence of RANKL stimulation. Although harmine promoted NFATc1 expression and stimulated target genes for osteoclastogenesis, cell-cell fusion and the formation of TRAP-positive multinucleated osteoclasts from RAW264.7 cells and BMMs was significantly inhibited by harmine treatment. Meanwhile, harmine remarkably promoted the expression of inhibitor of DNA binding/differentiation-2 (Id2), which is a negative regulator for osteoclastogenesis, in RAW264.7 cells and BMMs. An Id2-null-mutant showed slightly increased osteoclast formation from BMMs, and the harmine-mediated inhibition of osteoclast formation was abolished in the BMMs of Id2-null-mutant mice. These results suggest that harmine is a potent activator of NFATc1 that interferes with the function of DYRK1A in osteoclast precursors and also up-regulates Id2 protein, which may dominantly inhibit expression pathways associated with cell-cell fusion, thereby leading to

  8. Flight test evaluations of the head-up display and the inertial reference unit of the NAL QSTOL experimental aircraft (Aska) by the NAL B-65 Queen Air research aircraft. Teisoon STOL jikkenkiyo HUD (head up display) oyobi IRU (kansei kijun sochi) no hiko hyoka shiken

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    A head-up display (HUD) and an inertial reference unit (IRU) were developed by the National Aerospace Laboratory (NAL) for the NAL QSTOL (Quiet Short Take Off and Landing) experimental air craft (Aska). In order to evaluate both the performance of the HUD which provides the pilot with landing aid information, and the accuracy and characteristics of the IRU to be used for flight control and measurements, flight tests were conducted on board the B-65 Queen Air research aircraft. The results indicated that the characteristics of the HUD as an approach and landing aid system were good, and also that the IRU was useful as a sensor for flight control and measurements. Furthermore, it was shown that fundamental methods of evaluating the HUD characteristics and the IRU accuracy in actual flight were established for application of the HUD and the IRU to a new aircraft in the future. In addition, possibility of a new technology with landing aid information by means of the HUD was made clear. 21 refs., 48 figs., 14 tabs.

  9. Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells

    Directory of Open Access Journals (Sweden)

    Gutmann Anja

    2010-01-01

    Full Text Available Abstract Background ID proteins are dominant negative inhibitors of basic helix-loop-helix transcription factors that have multiple functions during development and cellular differentiation. Ectopic (over-expression of ID1 extends the lifespan of primary human epithelial cells. High expression levels of ID1 have been detected in multiple human malignancies, and in some have been correlated with unfavorable clinical prognosis. ID1 protein is localized at the centrosomes and forced (over-expression of ID1 results in errors during centrosome duplication. Results Here we analyzed the steady state expression levels of the four ID-proteins in 18 tumor cell lines and assessed the number of centrosome abnormalities. While expression of ID1, ID2, and ID3 was detected, we failed to detect protein expression of ID4. Expression of ID1 correlated with increased supernumerary centrosomes in most cell lines analyzed. Conclusions This is the first report that shows that not only ectopic expression in tissue culture but endogenous levels of ID1 modulate centrosome numbers. Thus, our findings support the hypothesis that ID1 interferes with centrosome homeostasis, most likely contributing to genomic instability and associated tumor aggressiveness.

  10. 1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (IDS) is encoded by multicopy genes in gymnosperms Ginkgo biloba and Pinus taeda.

    Science.gov (United States)

    Kim, Sang-Min; Kuzuyama, Tomohisa; Kobayashi, Akio; Sando, Tomoki; Chang, Yung-Jin; Kim, Soo-Un

    2008-01-01

    Isoprenoids are synthesized through the condensation of five-carbon intermediates, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), derived from two distinct biosynthetic routes: cytosolic mevalonate (MVA) and plastidial 2-C-methyl-D: -erythritol 4-phosphate (MEP) pathways. 1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (IDS; EC 1.17.1.2), which catalyzes the last step of MEP pathway, was cloned as a multicopy gene from gymnosperms Ginkgo biloba (GbIDS1, GbIDS2, and GbIDS2-1) and Pinus taeda (PtIDS1 and PtIDS2), and characterized. Phylogenetic tree constructed with other plant IDSs demonstrated gymnosperm IDSs were distinctively different from angiosperm IDSs. The gymnosperm IDS clade contained two subclades, one composed of GbIDS1 and PtIDS1, and the other composed of GbIDS2, GbIDS2-1, and PtIDS2. G. biloba IDSs, except GbIDS2-1, successfully complemented Escherichia coli DLYT1, a lytB disruptant, confirming the in vivo competency of isozymes. During the 4 weeks study period, although transcript levels of GbIDS1s were similar both in roots and leaves of cultured G. biloba embryo, the transcripts of GbIDS2 predominantly occurred in the embryo roots, where diterpene ginkgolides are biosynthesized. Levels of PtIDS2 transcripts in the diterpenoid resin-producing wood were 4-5 times higher than those in other tissues. Higher levels of GbIDS1 transcripts were induced by light, whereas those of GbIDS2 were increased by methyl jasmonate treatment. These results strongly imply GbIDS2 and PtIDS2 have high correlation with secondary metabolism. In Arabidopsis transient expression system, N-terminal 100 amino acid residues of GbIDS1 delivered fused GFP protein into chloroplast as well as cytosol and nucleus, whereas those of GbIDS2, GbIDS2-1, and two PtIDSs delivered GFP only into chloroplast.

  11. Ability of RapID Yeast Plus System to identify 304 clinically significant yeasts within 5 hours.

    OpenAIRE

    Kitch, T T; Jacobs, M R; McGinnis, M R; Appelbaum, P C

    1996-01-01

    The RapID Yeast Plus System (Innovative Diagnostic Systems, Norcross, Ga.) is a qualitative micromethod that uses conventional and chromogenic substrates for the identification of medically important yeasts. The ability of the RapID Yeast Plus system to accurately identify 304 clinical yeast isolates within 5 h was evaluated. The RapID Yeast Plus method correctly identified 286 (94.1%) of strains to the species level without the need for additional tests. A further 12 strains (3.9%) were clas...

  12. body mass (ID 1412), reduction of post-prandial glycaemic responses (ID 1414), and maintenance of a normal blood lipid profile (1421) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

    DEFF Research Database (Denmark)

    Tetens, Inge

    claims in relation to very low calorie diets (VLCDs) and reduction in body weight, reduction in the sense of hunger, reduction in body fat mass while maintaining lean body mass, reduction of post-prandial glycaemic responses, and maintenance of normal blood lipid profile. The scientific substantiation......), very low calorie diet is not sufficiently characterised in relation to: reduction of post-prandial glycaemic responses (ID 1414) and maintenance of normal blood lipid profile (ID 1421), mainly owing to the lack of standardisation of the type of available carbohydrates and of most of the fatty acids...... that formula foods for use in very low calorie diets should contain. The Panel concludes that a cause and effect relationship cannot be established between the consumption of a very low calorie diet and reduction of post-prandial glycaemic responses (ID 1414) and maintenance of normal blood lipid profile (ID...

  13. Research on ChromID Vibrio Agar for Detection Effect of Vibrio Cholera%弧菌显色培养基(ChromID Vibrio)对霍乱弧菌检测效果的探讨

    Institute of Scientific and Technical Information of China (English)

    沈飚; 胡兴娟; 汪云泉; 徐君辉

    2010-01-01

    [目的]探讨梅里埃弧菌显色培养基(简称ChromID Vibrio)对霍乱弧菌的检测效果.[方法]通过ChromID Vibrio弧菌显色培养基同硫代硫酸盐-柠檬酸盐-胆盐-蔗糖(简称TCBS)琼脂培养基进行比对,采用阳性菌株直接平板计数、人工污染样品和实际样品检测的方法,对ChromID Vibrio的灵敏性、特异性和检测效果进行了评价.[结果]ChromID Vibrio弧菌显色培养基上霍乱弧菌典型菌落是蓝绿色.阳性菌株直接平板计数及人工污染试验均表明ChromID Vibrio平板的敏感性均比TCBS平板高.对采集的300份实际样品进行检测,都未检出霍乱弧菌.[结论]ChromID Vibrio具有较好的灵敏性、特异性,能提高霍乱弧菌检测效率.

  14. CRED SVP Drifting Buoy Argos_ID 35650 Swain's Atoll, American Samoa, 200202-200211 (NODC Accession 0067474)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED SVP drifter Argos_ID 35650 was deployed in the region of American Samoa to assess ocean currents and sea surface temperature. SVP drifter data files contain...

  15. CRED SVP Drifting Buoy Argos_ID 35647 Data Tutuila, American Samoa, 200202-200307 (NODC Accession 0067474)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED SVP drifter Argos_ID 35647 was deployed in the region of American Samoa to assess ocean currents and sea surface temperature. SVP drifter data files contain...

  16. CRED APEX Drifting Buoy Argos_ID 25333 Data in the NW Hawaiian Islands, 200110-200204 (NODC Accession 0049436)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED APEX drifter Argos_ID 25333 was deployed in the region of NW Hawaiian Islands to assess ocean currents and sea surface temperature. APEX drifter data files...

  17. CRED SVP Drifting Buoy Argos_ID 30147 Data Nihoa, Northwestern Hawaiian Islands, 200209-200501 (NODC Accession 0049436)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED SVP drifter Argos_ID 30147 was deployed in the region of NW Hawaiian Islands to assess ocean currents and sea surface temperature. SVP drifter data files...

  18. CRED SVP Drifting Buoy Argos_ID 35648 Data Pago Pago, American Samoa, 200203-200204 (NODC Accession 0067474)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED SVP drifter Argos_ID 35648 was deployed in the region of American Samoa to assess ocean currents and sea surface temperature. SVP drifter data files contain...

  19. CRED SVP Drifting Buoy Argos_ID 30340 Data Kauai Channel, Main Hawaiian Islands, 200210-200409 (NODC Accession 0049436)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED SVP drifter Argos_ID 30340 was deployed in the region of Main Hawaiian Islands to assess ocean currents and sea surface temperature. SVP drifter data files...

  20. CRED APEX Drifting Buoy Argos_ID 25330 Data Maro Reef, Northwestern Hawaiian Islands, 200109-200201 (NODC Accession 0049436)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CRED APEX drifter Argos_ID 25330 was deployed in the region of NW Hawaiian Islands to assess ocean currents and sea surface temperature. APEX drifter data files...